LOCUS       DBGJFK010000001       141236 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.001, whole genome shotgun sequence.
ACCESSION   DBGJFK010000001 DBGJFK010000000
VERSION     DBGJFK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 141236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 141236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..141236
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.001"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..362
                     /locus_tag="ACOIAP_000001"
     CDS             <1..362
                     /locus_tag="ACOIAP_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGZ2636930.1"
                     /translation="KLSTKLIKENDIICIEDLQVKNMIGNHKLSRLISDVSWSEFVRQ
                     LKYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINA
                     SMNILKEGLRLITIQNK"
     gene            736..3291
                     /locus_tag="ACOIAP_000002"
     CDS             736..3291
                     /locus_tag="ACOIAP_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3656 domain-containing protein"
                     /protein_id="HGZ2636931.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELDVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNISAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDGERIKIKD
                     RKFKKNILKYQPNRVNKQKKLNTVPKIRVKVKNLEQLEAVLNYDVDLIYYEDINTLSK
                     ALQMVSSISIDSSISTDLDTSSSSSISKELMGSNPNNIDTLNNKRSNTAVTDKKLIYS
                     APRIVRNKEYKQFEILDNIKGINNVQIGNWGCMEYFKDKDLYIDCYLNAFNSESINHF
                     KEEGASTVCLSQELNLNEIKQTLKYTDVETEAVIYGYAPMMVTEYCPMGVVVRDCKKD
                     KRVAKCKESNYALRDFTDASYRITQDVFCRSTIYNSKVTCMLDNLCELDEIGIDVFRI
                     DFTVEDSEMVKKVIEAHIEVLSNNYKLGEKATDLYKKLDEIGTVAGHYYKGVE"
     gene            3395..3973
                     /locus_tag="ACOIAP_000003"
     CDS             3395..3973
                     /locus_tag="ACOIAP_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGZ2636932.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRDLAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            4007..4483
                     /locus_tag="ACOIAP_000004"
     CDS             4007..4483
                     /locus_tag="ACOIAP_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGZ2636933.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYNNGKLKDYNVSFLD"
     gene            5017..5838
                     /locus_tag="ACOIAP_000005"
     CDS             5017..5838
                     /locus_tag="ACOIAP_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2636934.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVVEYNRESFELEPEKLLNFIKFRRSIRQYKDIEIEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIEGLYNLALNTDDNDPVRSMYKNT
                     FKKMYKRYKENGKDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVI"
     gene            6075..8576
                     /locus_tag="ACOIAP_000006"
     CDS             6075..8576
                     /locus_tag="ACOIAP_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGZ2636935.1"
                     /translation="MNLKKLLLLIIVITSIFTSYIFSFSINAIANDNRTIRIAYPIQK
                     GLTEIDEQGNYYGYTYEYLLEIAQYTGWNYEFVQVPGDINESITKLMKMLENGEIDIM
                     GGTLYNESLQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQGVKKIRIAVIENSDT
                     RLKELDEYCKMNLMSPELVYCKTNEEQLEALKNGKADVLLNVSMNPIEDVRTVAKFSS
                     RPFYFITPKGSTDLTQRLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDEETNYI
                     KDTEKLKVGVLLNKPPFQNIDKNTGELKGISIDLLNHICDLTGLEFELVPIKSQKDLE
                     KMTKNHEIEIVAGIIYDYEYSRKHNIIMSRPFVSTQYAMMINNKLNENSLDGKCLALT
                     RGLNYEGQFKENIVWYDTLEECIEAVNKGDVDYTYGEGYSMQYYMNQPKYKNVRLVPQ
                     TYEAQSICFGIIKKDKQELLNIFNKAITSISSEKMQSIVYQNTTYRQDFSLLYIMQQN
                     PIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFEYDYKQ
                     DKLIISMPEKGIETYYGLDKNDRESENNNNIANEIDKIRREYNKKFFDVIKSQENGTT
                     EMYSIVFDDTFHWIRITSKIIYNDRKIPMYVIGKISNIDYEKEEKNRLLDKVQRDSLT
                     NIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLVGDKILIDVAKVL
                     DESFTKDDIVGRLGGDEFSVYINDIINNEELINKCNDVYNRIHLIKLPNGKSLSISMG
                     VVIAKCGQEYDELYQIADNALYDSKREGRNRFKIV"
     gene            complement(8780..10231)
                     /locus_tag="ACOIAP_000007"
     CDS             complement(8780..10231)
                     /locus_tag="ACOIAP_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HGZ2636936.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLITVNEEDGMNGADALDPSL
                     IKGQYILNLDSEEEGYLLVSCAGGKTCVVSLPVEYKKVEGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLDVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKDSKLEKICCETYERLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANIWDYVIEILKSMNQY"
     gene            10548..12926
                     /locus_tag="ACOIAP_000008"
     CDS             10548..12926
                     /locus_tag="ACOIAP_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGZ2636937.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKAEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTTDSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKSGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIERLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTHKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            12994..13407
                     /locus_tag="ACOIAP_000009"
     CDS             12994..13407
                     /locus_tag="ACOIAP_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HGZ2636938.1"
                     /translation="MILVSACLIGINCKYSGDNNENEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGINVKSEKDL"
     gene            13733..15433
                     /gene="argS"
                     /locus_tag="ACOIAP_000010"
     CDS             13733..15433
                     /gene="argS"
                     /locus_tag="ACOIAP_000010"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGZ2636939.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFAK
                     LENGDEEAKELWQWFRDESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKH
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLRLLGMHAPERM
                     "
     gene            15687..16610
                     /locus_tag="ACOIAP_000011"
     CDS             15687..16610
                     /locus_tag="ACOIAP_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2636940.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLIIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVTYFKKE
                     KLLFEYLLSSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKFEDYDEESILLNILNVLYDVYMEDRTVEDEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKKIDPRSLIRLEEGNTIIDPIFNQ
                     ITVISKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(16615..16821)
                     /locus_tag="ACOIAP_000012"
     CDS             complement(16615..16821)
                     /locus_tag="ACOIAP_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2636941.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            16957..18711
                     /locus_tag="ACOIAP_000013"
     CDS             16957..18711
                     /locus_tag="ACOIAP_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HGZ2636942.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVDMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYDAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQNLDE
                     IPSPYENLNPREYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLERIKRDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREAENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            18729..19871
                     /locus_tag="ACOIAP_000014"
     CDS             18729..19871
                     /locus_tag="ACOIAP_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGZ2636943.1"
                     /translation="MDFKIEKYLLRKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     AYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEEVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEIQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(20045..20983)
                     /locus_tag="ACOIAP_000015"
     CDS             complement(20045..20983)
                     /locus_tag="ACOIAP_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2636944.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIIELEEELG
                     VKLLVRGNRKITLTNEGKLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGGGETEA
                     MRLIARTAHNFHQKYPNVKYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYTQI
                     PATDVWGLLMRKDSTLASQNTINPKDLCNIPLIISRQTLVDKAISKWLQDSTEKLNIV
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSILLDTSELDISKLNTPEVK"
     gene            21209..21787
                     /locus_tag="ACOIAP_000016"
     CDS             21209..21787
                     /locus_tag="ACOIAP_000016"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HGZ2636945.1"
                     /translation="MNINEFLTHVNQGKPVSSKSEIHKFMVKLSNEAMRITSELNSYY
                     HEPEEIHSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKDVAENTIVGGVPAKILRVIDKITE"
     gene            21902..22813
                     /locus_tag="ACOIAP_000017"
     CDS             21902..22813
                     /locus_tag="ACOIAP_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HGZ2636946.1"
                     /translation="MIKKLDDILDQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKVKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGDNVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            23420..25339
                     /gene="cooS"
                     /locus_tag="ACOIAP_000018"
     CDS             23420..25339
                     /gene="cooS"
                     /locus_tag="ACOIAP_000018"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HGZ2636947.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMEADAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            25648..26427
                     /locus_tag="ACOIAP_000019"
     CDS             25648..26427
                     /locus_tag="ACOIAP_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2636948.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            26676..28352
                     /locus_tag="ACOIAP_000020"
     CDS             26676..28352
                     /locus_tag="ACOIAP_000020"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGZ2636949.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNEENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKALGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFKFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLERLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            28437..29069
                     /locus_tag="ACOIAP_000021"
     CDS             28437..29069
                     /locus_tag="ACOIAP_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HGZ2636950.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVDKVKTEVDKLVEDGVKICDEVYTKVEKALGK"
     gene            29161..30033
                     /locus_tag="ACOIAP_000022"
     CDS             29161..30033
                     /locus_tag="ACOIAP_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HGZ2636951.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQDEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSSVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLNKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            30068..30742
                     /locus_tag="ACOIAP_000023"
     CDS             30068..30742
                     /locus_tag="ACOIAP_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HGZ2636952.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKVLGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNAENDCAWIKIYERLEAIGQLDNLVEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            30778..31659
                     /locus_tag="ACOIAP_000024"
     CDS             30778..31659
                     /locus_tag="ACOIAP_000024"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HGZ2636953.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRVAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            31703..33088
                     /gene="lpdA"
                     /locus_tag="ACOIAP_000025"
     CDS             31703..33088
                     /gene="lpdA"
                     /locus_tag="ACOIAP_000025"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGZ2636954.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVIEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            33144..33914
                     /locus_tag="ACOIAP_000026"
     CDS             33144..33914
                     /locus_tag="ACOIAP_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase accessory protein
                     CooC"
                     /protein_id="HGZ2636955.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            33934..34878
                     /gene="acsD"
                     /locus_tag="ACOIAP_000027"
     CDS             33934..34878
                     /gene="acsD"
                     /locus_tag="ACOIAP_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HGZ2636956.1"
                     /translation="MTFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NPPKIGIQISDVYPESWTDSYKELYKDVAKCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYSHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            34909..36276
                     /gene="acsC"
                     /locus_tag="ACOIAP_000028"
     CDS             34909..36276
                     /gene="acsC"
                     /locus_tag="ACOIAP_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HGZ2636957.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDSKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRIALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            36326..37132
                     /gene="acsE"
                     /locus_tag="ACOIAP_000029"
     CDS             36326..37132
                     /gene="acsE"
                     /locus_tag="ACOIAP_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase/acetyl-CoA
                     synthase methytransferase subunit"
                     /protein_id="HGZ2636958.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            37189..39315
                     /gene="acsB"
                     /locus_tag="ACOIAP_000030"
     CDS             37189..39315
                     /gene="acsB"
                     /locus_tag="ACOIAP_000030"
                     /EC_number="2.3.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit alpha/beta"
                     /protein_id="HGZ2636959.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            39402..39779
                     /gene="gcvH"
                     /locus_tag="ACOIAP_000031"
     CDS             39402..39779
                     /gene="gcvH"
                     /locus_tag="ACOIAP_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HGZ2636960.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            39891..41819
                     /gene="acsV"
                     /locus_tag="ACOIAP_000032"
     CDS             39891..41819
                     /gene="acsV"
                     /locus_tag="ACOIAP_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="corrinoid activation/regeneration protein AcsV"
                     /protein_id="HGZ2636961.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTIFRKSDFKVTITYVQKQKKLTIINIEEGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            41844..42716
                     /locus_tag="ACOIAP_000033"
     CDS             41844..42716
                     /locus_tag="ACOIAP_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGZ2636962.1"
                     /translation="MNKNLSEKVKVAFDIKLKNFGNKIEFAYPNQTLALSTTNNKCSL
                     KCAHCNGHYLNNMVPIEDYEEKVQSRNITSFLLSGGCSYDGDVPMSTHIQTIKRLKEQ
                     GYRLNAHLGLMDKESIIELCKYLDIVSFDLVFDKETIREVYKMEKSKDDYIEVYNTIR
                     ENTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIILIPTKGTEYENVEPPELE
                     RVADILCEARINLPYTEINLGCMRPRGVYRKELDQLSIMCGVNKIVLPSRSAKNKAIE
                     MNMTITECKECCVL"
     gene            42713..43651
                     /locus_tag="ACOIAP_000034"
     CDS             42713..43651
                     /locus_tag="ACOIAP_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGZ2636963.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVVWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQINKFFSAGVDKIGIAIDAANKELYEKIKGNNYNEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKGNDITISLFAFTPVRGTKMEKIN
                     QPNIESYRRVQLMSYMINKGYSKEYFTFKNGYLDSIKLDNDIVKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            43698..44513
                     /locus_tag="ACOIAP_000035"
     CDS             43698..44513
                     /locus_tag="ACOIAP_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HGZ2636964.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLAKELYEKYKNEEYNKKR"
     gene            44664..44855
                     /locus_tag="ACOIAP_000036"
     CDS             44664..44855
                     /locus_tag="ACOIAP_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HGZ2636965.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            44874..45290
                     /locus_tag="ACOIAP_000037"
     CDS             44874..45290
                     /locus_tag="ACOIAP_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HGZ2636966.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            45306..45656
                     /locus_tag="ACOIAP_000038"
     CDS             45306..45656
                     /locus_tag="ACOIAP_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HGZ2636967.1"
                     /translation="MIFDREIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            45925..46704
                     /gene="hisJ"
                     /locus_tag="ACOIAP_000039"
     CDS             45925..46704
                     /gene="hisJ"
                     /locus_tag="ACOIAP_000039"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HGZ2636968.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDIGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKANL
                     NKYGEELEDSLLSVHIIKIDDDYYCVDYSIEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEDLIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDIV"
     gene            complement(47020..47895)
                     /locus_tag="ACOIAP_000040"
     CDS             complement(47020..47895)
                     /locus_tag="ACOIAP_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGZ2636969.1"
                     /translation="MKKRLIIILSLVLVLSSVLTIFAYSNIKYNNKLIYSNMIDKRTQ
                     NSVEEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPYNL
                     EKLQDNWMKKFPDYMDVNCRITAFRLFKDFINSNNKFTGDSIDLNVDLDTIMNNKDAK
                     FSTKDVEKFINFFSAIPAKDTSDISKIAEQIKNEWKKRKISFKNNKNISIINGFLRYP
                     ETKNVFIGHTGICIKTKNGILFVEKYGPTSPYQVTKFKNKKDVKNYMFNRLKMSESEI
                     ELPDPVIMENDKLMK"
     gene            48447..48959
                     /locus_tag="ACOIAP_000041"
     CDS             48447..48959
                     /locus_tag="ACOIAP_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2636970.1"
                     /translation="MKVKKFKSGIVMALTVMVIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKVNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNVILREEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(49264..50361)
                     /locus_tag="ACOIAP_000042"
     CDS             complement(49264..50361)
                     /locus_tag="ACOIAP_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HGZ2636971.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLNILEKYIIEHSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQDIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVDEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSRLEIKKVI"
     gene            50654..52180
                     /gene="glpK"
                     /locus_tag="ACOIAP_000043"
     CDS             50654..52180
                     /gene="glpK"
                     /locus_tag="ACOIAP_000043"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGZ2636972.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDKELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTNQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            52221..53336
                     /locus_tag="ACOIAP_000044"
     CDS             52221..53336
                     /locus_tag="ACOIAP_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HGZ2636973.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGVIGGLIA
                     GFNLSMVIINMIPVIILSVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(53617..54381)
                     /locus_tag="ACOIAP_000045"
     CDS             complement(53617..54381)
                     /locus_tag="ACOIAP_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGZ2636974.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            54640..54730
                     /locus_tag="ACOIAP_000046"
     tRNA            54640..54730
                     /locus_tag="ACOIAP_000046"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:54674..54676,aa:Ser,seq:gct)
     gene            54818..55606
                     /locus_tag="ACOIAP_000047"
     CDS             54818..55606
                     /locus_tag="ACOIAP_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HGZ2636975.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISDNN
                     ELDPFIKKGLELMVDGVDAVTIRSILESQIQITSKRHKEGIAIFDSAGGYAPTMGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            55627..56367
                     /locus_tag="ACOIAP_000048"
     CDS             55627..56367
                     /locus_tag="ACOIAP_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HGZ2636976.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDNLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAVVKDNSREKIIQIGKMLNEMNSYIRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSNDK"
     gene            56545..56913
                     /locus_tag="ACOIAP_000049"
     CDS             56545..56913
                     /locus_tag="ACOIAP_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2636977.1"
                     /translation="MGNKNTKYKDKTRERYNKKVENLNKEKLNKANKESKKVDKIDDI
                     INKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVKAL
                     FSIFVIVCFLIAFKYVVNPV"
     gene            57005..58465
                     /locus_tag="ACOIAP_000050"
     CDS             57005..58465
                     /locus_tag="ACOIAP_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGZ2636978.1"
                     /translation="MNRCKFAKLIITLMIVLLLTGCSLKKEDNYKLDPENPISIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGSERGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELSEYIDEYVEEGRINSKGEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFNGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLEVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDLNKINELV
                     KSGTSKKDAVAQFNNDKNFETWFESFKAELEKAIKK"
     gene            58518..61547
                     /locus_tag="ACOIAP_000051"
     CDS             58518..61547
                     /locus_tag="ACOIAP_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2636979.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEARINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIRIISNDLIYLLRKNSVTGAFIILSDKNIKDNPVDSNGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQEGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRIMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNDDMAFENVISNGYSLKEKFWNGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLNLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYVASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNADNVFCTKEFFSVFITESKFEEYGYMEK
                     SKFLKKLRGLDKYLQESYETENTYIYKFESKDKKPKWVRLNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKVAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSINYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGI
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            61624..63690
                     /locus_tag="ACOIAP_000052"
     CDS             61624..63690
                     /locus_tag="ACOIAP_000052"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HGZ2636980.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLKNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLISSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKVIKCSQGDGGSVTYISPHDSEEEAL
                     YIAKEIIDEIKKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    64218..64428
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            64652..65467
                     /locus_tag="ACOIAP_000053"
     CDS             64652..65467
                     /locus_tag="ACOIAP_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGZ2636981.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDSGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKNVTEGMAAAIKKADNNKEFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            65495..66172
                     /locus_tag="ACOIAP_000054"
     CDS             65495..66172
                     /locus_tag="ACOIAP_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGZ2636982.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            66231..66953
                     /locus_tag="ACOIAP_000055"
     CDS             66231..66953
                     /locus_tag="ACOIAP_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGZ2636983.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEVLLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            67600..68751
                     /locus_tag="ACOIAP_000056"
     CDS             67600..68751
                     /locus_tag="ACOIAP_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGZ2636984.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     GIKEVRQDVAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKSAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVNNLKNTLKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSHV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            68797..69972
                     /gene="thiI"
                     /locus_tag="ACOIAP_000057"
     CDS             68797..69972
                     /gene="thiI"
                     /locus_tag="ACOIAP_000057"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGZ2636985.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGKFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIDA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDKINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            70093..70218
                     /locus_tag="ACOIAP_000058"
                     /pseudo
     CDS             70093..70218
                     /locus_tag="ACOIAP_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin protein"
     gene            70273..70911
                     /locus_tag="ACOIAP_000059"
     CDS             70273..70911
                     /locus_tag="ACOIAP_000059"
                     /inference="COORDINATES: protein motif:HMM:NF037759.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HGZ2636986.1"
                     /translation="MAEEPSKDKNKVIKDVLENKDGKYFETEPKCKSGGIYSATFDDG
                     YDGITGGESIAKVYVTCTEHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKSNDDF
                     RKYLLDNKYKKGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKPDATVVVFANNKTGGN
                     WYTSLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            71154..71795
                     /locus_tag="ACOIAP_000060"
     CDS             71154..71795
                     /locus_tag="ACOIAP_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HGZ2636987.1"
                     /translation="MINNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKAISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDVGILTGNITTAAQALGLGSCIIGMIRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYREILDIPEGYSVPFGIAIGIPDGNLPNAREVVYKVSRV"
     gene            complement(72194..72928)
                     /gene="pflA"
                     /locus_tag="ACOIAP_000061"
     CDS             complement(72194..72928)
                     /gene="pflA"
                     /locus_tag="ACOIAP_000061"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGZ2636988.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSDGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDVDNLEKLGKFVATLKNVERFELLPYHSMGIHKWENLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(73088..75319)
                     /gene="pflB"
                     /locus_tag="ACOIAP_000062"
     CDS             complement(73088..75319)
                     /gene="pflB"
                     /locus_tag="ACOIAP_000062"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGZ2636989.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDKAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            75678..76673
                     /locus_tag="ACOIAP_000063"
     CDS             75678..76673
                     /locus_tag="ACOIAP_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HGZ2636990.1"
                     /translation="MFITVVLFLVGFLLITKGADIFINCTVEIGRKTNISEIILGATI
                     VSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICNTGLALGLVVFLSPFNVDKKMFF
                     SKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIFYMVNNYRSVVGKSDTKSRNIKN
                     NTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMMIIGSQILIESGVRIASFLNIPQ
                     GIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNILGANILNIVSVIAISAIPNNIP
                     ILSQNRQLDIPFMILLILIVIIPTLKSNRLSRIQGILMLFTYFLYISILYFMYII"
     gene            76764..78377
                     /locus_tag="ACOIAP_000064"
     CDS             76764..78377
                     /locus_tag="ACOIAP_000064"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGZ2636991.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLENFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            78784..80769
                     /locus_tag="ACOIAP_000065"
     CDS             78784..80769
                     /locus_tag="ACOIAP_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2636992.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSSVLGVSTRTIRNYIN
                     QINRELKDGIAKIVKNEKGTYSIRVEDESKLIEIVNFNRVKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLVLDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIISALRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIEDAILLKNSINIKSIK
                     KIEKNIPFIGKLIEEDKFFILNKGTFMENLEEMLEKLVLKGIIDIEFKENVLKREKKS
                     STALDNYIALPHSVSPNEENLYLAFGILENPVIWDTKEIRIIILMIIPDKNVGSTELI
                     IKSYEEVLEIGRDKKIVEKLSKVKSFDEFYKIITTRR"
     gene            80774..81208
                     /locus_tag="ACOIAP_000066"
     CDS             80774..81208
                     /locus_tag="ACOIAP_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HGZ2636993.1"
                     /translation="MDPVIFIIVSFIVVYLLNIFLGYLQIKDFNKNYIELKRKGRVAI
                     GRKKGRISSGAIVLILINDDGVIIETRKMQGVTVVARVKSFEGLVGKNLKYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDMSNLSTDEECRMEVV"
     gene            81237..81797
                     /locus_tag="ACOIAP_000067"
     CDS             81237..81797
                     /locus_tag="ACOIAP_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HGZ2636994.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            81861..82361
                     /locus_tag="ACOIAP_000068"
                     /pseudo
     CDS             81861..82361
                     /locus_tag="ACOIAP_000068"
                     /inference="COORDINATES: protein motif:HMM:NF015569.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbitol transporter subunit IIB"
     gene            82401..82820
                     /locus_tag="ACOIAP_000069"
     CDS             82401..82820
                     /locus_tag="ACOIAP_000069"
                     /inference="COORDINATES: protein motif:HMM:NF019286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbitol transporter subunit IIB"
                     /protein_id="HGZ2636995.1"
                     /translation="MAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFP
                     LLSPFLGPGAVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAE
                     AEPDTVQVGVPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            82861..83226
                     /locus_tag="ACOIAP_000070"
     CDS             82861..83226
                     /locus_tag="ACOIAP_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGZ2636996.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTNDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            83326..84099
                     /gene="srlD"
                     /locus_tag="ACOIAP_000071"
     CDS             83326..84099
                     /gene="srlD"
                     /locus_tag="ACOIAP_000071"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HGZ2636997.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAK
                     EIEMEFGCKSVGYGCNAIDEIQVMSTIKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFMDVANILTFYASKEAEYCTGQSINITGGQVM"
     gene            84447..86555
                     /locus_tag="ACOIAP_000072"
     CDS             84447..86555
                     /locus_tag="ACOIAP_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HGZ2636998.1"
                     /translation="MDITKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDEVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGSPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYIQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKRYLYSLELSFLIDECGVKENDIREL
                     VALYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSKLYGQDREFYVSNISKFIEESLRNTSNKINNVSDEPDTKSNKTDYISNDLY
                     SLSGKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCFDMFMTDTATLCD
                     LFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFMELAKKMRLNDYPF
                     VEKSTYLEKVIEPLKCVDKNLDIEKLKNNYFTIHNPVAWEDKKFETPSGKYELYSESI
                     KNLGINPTPVYINNKYKEIEDKNENISFRLLTNHHADTLFSQHFMDKKSIAQAYINQR
                     MAKKVGIKDKDTVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHGNPNILTDTGI
                     SDFGGQVTYNESIVEIIRQN"
     gene            86642..86977
                     /gene="spoIIAA"
                     /locus_tag="ACOIAP_000073"
     CDS             86642..86977
                     /gene="spoIIAA"
                     /locus_tag="ACOIAP_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045152 - antisigma factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HGZ2636999.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            86991..87419
                     /gene="spoIIAB"
                     /locus_tag="ACOIAP_000074"
     CDS             86991..87419
                     /gene="spoIIAB"
                     /locus_tag="ACOIAP_000074"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA];
                     GO_process: GO:0042174 - negative regulation of
                     sporulation resulting in formation of a cellular spore
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HGZ2637000.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            87442..88206
                     /gene="sigF"
                     /locus_tag="ACOIAP_000075"
     CDS             87442..88206
                     /gene="sigF"
                     /locus_tag="ACOIAP_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HGZ2637001.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            88493..88930
                     /gene="spoVAC"
                     /locus_tag="ACOIAP_000076"
     CDS             88493..88930
                     /gene="spoVAC"
                     /locus_tag="ACOIAP_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HGZ2637002.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            89084..90097
                     /gene="spoVAD"
                     /locus_tag="ACOIAP_000077"
     CDS             89084..90097
                     /gene="spoVAD"
                     /locus_tag="ACOIAP_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HGZ2637003.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLTDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGEGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGIDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            90110..90472
                     /gene="spoVAE"
                     /locus_tag="ACOIAP_000078"
     CDS             90110..90472
                     /gene="spoVAE"
                     /locus_tag="ACOIAP_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HGZ2637004.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            90656..91672
                     /locus_tag="ACOIAP_000079"
     CDS             90656..91672
                     /locus_tag="ACOIAP_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGZ2637005.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAMFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            92046..92888
                     /locus_tag="ACOIAP_000080"
     CDS             92046..92888
                     /locus_tag="ACOIAP_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HGZ2637006.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTART
                     SNKL"
     gene            92903..93367
                     /locus_tag="ACOIAP_000081"
     CDS             92903..93367
                     /locus_tag="ACOIAP_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637007.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLKLNGML"
     gene            93381..94526
                     /locus_tag="ACOIAP_000082"
     CDS             93381..94526
                     /locus_tag="ACOIAP_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2637008.1"
                     /translation="MNELKVKIKEEIKLLSEEKKTSFEKVSDYLFSNPELAFEEYKSQ
                     KALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPGMGHACGHNI
                     IGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFNNVDAALILH
                     PSDASMPDDISFAQVNLKFDFSGKASHAAAFPWEGKSALSGVIALFNSVNSMRLHLKD
                     YARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKGAAISTGTSV
                     EIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGNLTHEIPAIQ
                     AYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            94570..95505
                     /locus_tag="ACOIAP_000083"
     CDS             94570..95505
                     /locus_tag="ACOIAP_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HGZ2637009.1"
                     /translation="MILKQVIEVYDILDKADANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKSKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(96131..98824)
                     /locus_tag="ACOIAP_000084"
     CDS             complement(96131..98824)
                     /locus_tag="ACOIAP_000084"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HGZ2637010.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWDLISSDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLDLKYIKQSEYDEAIKAKIEIKLPKSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDKNSNFPGHMAGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQST
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKKAPEEHKVVDPEVAYVVTDMLESVITEGTGGVAALPN
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKVMQKIHANLTVTEFEVPKNVYFTKINLDDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQQQENNNNNNNSGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNSGGGSTNTPDGGGTPAT"
     gene            99039..99737
                     /gene="yunB"
                     /locus_tag="ACOIAP_000085"
     CDS             99039..99737
                     /gene="yunB"
                     /locus_tag="ACOIAP_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HGZ2637011.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(99949..100956)
                     /locus_tag="ACOIAP_000086"
     CDS             complement(99949..100956)
                     /locus_tag="ACOIAP_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HGZ2637012.1"
                     /translation="MQLKNFHFKDNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNECKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLTQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            101184..102068
                     /locus_tag="ACOIAP_000087"
     CDS             101184..102068
                     /locus_tag="ACOIAP_000087"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2637013.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKGENSNKNNKDKEEDKSNSKSNKDKLSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKNILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIIQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDEYFK"
     gene            102270..103820
                     /locus_tag="ACOIAP_000088"
     CDS             102270..103820
                     /locus_tag="ACOIAP_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGZ2637014.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQDYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            103848..104483
                     /locus_tag="ACOIAP_000089"
     CDS             103848..104483
                     /locus_tag="ACOIAP_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGZ2637015.1"
                     /translation="MKKFLNVLFSVCISIVIIVGVINFTVGFKKLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFNLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLIVSLVGIILSVKNKNIKILKTTSITLIMMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPNLDPVINILPEEFFFHSGMMILILILLSSILLFVMYKLCKYFKIK"
     gene            complement(104589..104849)
                     /locus_tag="ACOIAP_000090"
     CDS             complement(104589..104849)
                     /locus_tag="ACOIAP_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HGZ2637016.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCMLPHKKDNYNYIMGKFQDLVKITSKK"
     gene            105066..106349
                     /gene="hflX"
                     /locus_tag="ACOIAP_000091"
     CDS             105066..106349
                     /gene="hflX"
                     /locus_tag="ACOIAP_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGZ2637017.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTSESMEELKELTKAAGAE
                     VVGSLIQNKHSIDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGENGITLDVDLDEEDFNIYREYILEK"
     gene            106357..107034
                     /locus_tag="ACOIAP_000092"
     CDS             106357..107034
                     /locus_tag="ACOIAP_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HGZ2637018.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDESSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            107121..107564
                     /locus_tag="ACOIAP_000093"
     CDS             107121..107564
                     /locus_tag="ACOIAP_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGZ2637019.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVFAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            107873..108517
                     /locus_tag="ACOIAP_000094"
     CDS             107873..108517
                     /locus_tag="ACOIAP_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGZ2637020.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVVVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLESGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTIYEDNVEIVVYSRLEDVDKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILL"
     gene            complement(108603..108980)
                     /locus_tag="ACOIAP_000095"
     CDS             complement(108603..108980)
                     /locus_tag="ACOIAP_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HGZ2637021.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGVF
                     LLLVGLFEVKKGFCAKSNKKPLN"
     gene            complement(108980..109366)
                     /locus_tag="ACOIAP_000096"
     CDS             complement(108980..109366)
                     /locus_tag="ACOIAP_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGZ2637022.1"
                     /translation="MKKTDGLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTTSSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            109544..110299
                     /gene="nadE"
                     /locus_tag="ACOIAP_000097"
     CDS             109544..110299
                     /gene="nadE"
                     /locus_tag="ACOIAP_000097"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HGZ2637023.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPSQPPKF"
     gene            110382..111101
                     /locus_tag="ACOIAP_000098"
     CDS             110382..111101
                     /locus_tag="ACOIAP_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGZ2637024.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKDGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            111845..112639
                     /locus_tag="ACOIAP_000099"
     CDS             111845..112639
                     /locus_tag="ACOIAP_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HGZ2637025.1"
                     /translation="MESIMENLNNLKVEVKDKVCVITINRPKALNALNNDTLRELSQV
                     IDVISENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESIKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKSALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            112733..114073
                     /locus_tag="ACOIAP_000100"
     CDS             112733..114073
                     /locus_tag="ACOIAP_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HGZ2637026.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFVVGSTILYKMVSKEKANGGHFIA
                     HESDVFDESEATNSKKENGPNGVIALIPLIISILIINVKINGQAIVPIEVGVFIGALL
                     VYLLLNKYQDNAKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            114210..115442
                     /locus_tag="ACOIAP_000101"
     CDS             114210..115442
                     /locus_tag="ACOIAP_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiB/BaiF CoA transferase family protein"
                     /protein_id="HGZ2637027.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSKAGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            115482..116624
                     /gene="acrC"
                     /locus_tag="ACOIAP_000102"
     CDS             115482..116624
                     /gene="acrC"
                     /locus_tag="ACOIAP_000102"
                     /EC_number="1.3.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0043958 - acryloyl-CoA reductase (NADH)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acryloyl-CoA reductase"
                     /protein_id="HGZ2637028.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASHTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            116635..117429
                     /locus_tag="ACOIAP_000103"
     CDS             116635..117429
                     /locus_tag="ACOIAP_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HGZ2637029.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKINVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            117443..118462
                     /locus_tag="ACOIAP_000104"
     CDS             117443..118462
                     /locus_tag="ACOIAP_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HGZ2637030.1"
                     /translation="MRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLAD
                     QLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERKK
                     PEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMATI
                     VCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVN
                     LTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTT
                     VRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSMCDYGIVGDLYEIIPEMI
                     ESLNR"
     gene            118561..119937
                     /locus_tag="ACOIAP_000105"
     CDS             118561..119937
                     /locus_tag="ACOIAP_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HGZ2637031.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGHSIQSIIPNTKMLDVMRDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENKDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(120268..120612)
                     /locus_tag="ACOIAP_000106"
     CDS             complement(120268..120612)
                     /locus_tag="ACOIAP_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637032.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIEKFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            121100..122110
                     /locus_tag="ACOIAP_000107"
     CDS             121100..122110
                     /locus_tag="ACOIAP_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HGZ2637033.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGTALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGLALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALCDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     IF"
     gene            122246..122734
                     /locus_tag="ACOIAP_000108"
     CDS             122246..122734
                     /locus_tag="ACOIAP_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2637034.1"
                     /translation="MKITILYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTVVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FN"
     gene            122797..124725
                     /locus_tag="ACOIAP_000109"
     CDS             122797..124725
                     /locus_tag="ACOIAP_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2637035.1"
                     /translation="MVWHIEYEVFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIEKIPIFITFLLNQIYSLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLLICIILSITNPFTHILFGLSKETGYIRGCGYVATFSSFFFYAIYSALL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLVHIHDVNHVYRIGGDIFSIVVNSQLGIKPEDLIKKIEERFKKTWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKRKHVIKNCL
                     EEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFITIAEQTGLINL
                     IGLVVFEKVCRFIASDEFEGLKLDNIAVNLSVVQCMQKNLADDLLYLMDKYNISPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIGYSGVSNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PIPEDAFKNLLKENAFTG"
     gene            124924..125334
                     /locus_tag="ACOIAP_000110"
     CDS             124924..125334
                     /locus_tag="ACOIAP_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGZ2637036.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            125356..125658
                     /locus_tag="ACOIAP_000111"
     CDS             125356..125658
                     /locus_tag="ACOIAP_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HGZ2637037.1"
                     /translation="MNKKIVAVCESERSLNSLKMAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(125830..126525)
                     /locus_tag="ACOIAP_000112"
     CDS             complement(125830..126525)
                     /locus_tag="ACOIAP_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCD domain-containing protein"
                     /protein_id="HGZ2637038.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKIDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATRLAILNATSKEIQKIKYTYLKSIEELDKVSQGLIEECYDADLQFHKEIILAS
                     HNPIFIRYYELIPKTISSNQYFGFKYRNSLKDMISHHNNIIIAFDSKDSNLGYTSMYN
                     HLEDVIQLFQHDD"
     gene            complement(126551..127738)
                     /locus_tag="ACOIAP_000113"
     CDS             complement(126551..127738)
                     /locus_tag="ACOIAP_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2637039.1"
                     /translation="MKKTSNQKLLLLSIVTFFWFSQYVYIPFQSPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFFPEGNGFLLAN
                     ILSGISSSTWISYMVHYTNFFSKEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKMPKKISIKKYLSICKDKRLIFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVISSGFASTKFCTKYEPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQRSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIRYGYFVLAIIAIVASILSYTYYKKLDLTLNYDI
                     IQS"
     gene            128074..129951
                     /locus_tag="ACOIAP_000114"
     CDS             128074..129951
                     /locus_tag="ACOIAP_000114"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGZ2637040.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKIEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNEVGKKNESEEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEEAVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVIMLPATLFLFGPIGIYIGNII
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AVGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSFIKVETKDGAIDITSPVEGECIELSEVKDDVFASKAMGEGIAILP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            130282..131688
                     /locus_tag="ACOIAP_000115"
     CDS             130282..131688
                     /locus_tag="ACOIAP_000115"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGZ2637041.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYNNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGIDFYNKII
                     DKLIECDIEPFVTLYHFDLPFTLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMRYLEKRNIVPHM
                     EDGDKEVLKKAKMDFIAVNYYRTNCAGAFPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACRLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            131716..132564
                     /locus_tag="ACOIAP_000116"
     CDS             131716..132564
                     /locus_tag="ACOIAP_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGZ2637042.1"
                     /translation="MYITKVLNNSLLLARDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLELPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSKEKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            133224..133916
                     /locus_tag="ACOIAP_000117"
     CDS             133224..133916
                     /locus_tag="ACOIAP_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637043.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEHIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKNDNYSKVHGLRAGADDYLTKP
                     FEIAEFTARVLSLIRRYTRFNPKNEESQQLSFKGLLIDLDQHTVTTNGETMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            133913..134848
                     /locus_tag="ACOIAP_000118"
     CDS             133913..134848
                     /locus_tag="ACOIAP_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2637044.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYIEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLDFEIDIPENRLMVNLDSDGYSRVVNNLVQN
                     VLAHSKARRIKITMSEDSKMVLLRVEDNGVGIAKENLQHIFERLYKCDKGRSKKGSGL
                     GLSIVSQMVERMGGKISVESEIGKYTVFIVSLPLI"
     gene            134998..135921
                     /locus_tag="ACOIAP_000119"
     CDS             134998..135921
                     /locus_tag="ACOIAP_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637045.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGSGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRNLCTERGKTILISSHILSEIALLADDIGIIDRGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLEIQLNLKNFKVADNHNIMLYDTDVSVAEINRAF
                     IQNNIDVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            135905..136675
                     /locus_tag="ACOIAP_000120"
     CDS             135905..136675
                     /locus_tag="ACOIAP_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637046.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIVFGIMFFVTALPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICIIYKKQEN"
     gene            136685..137467
                     /locus_tag="ACOIAP_000121"
     CDS             136685..137467
                     /locus_tag="ACOIAP_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637047.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQIVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFVITLIGGYLINREYTDQTLKNILTIPISLRKLLVGKL
                     IAVGGITVLLSIFSFLCTFILGLLFCNINISVILVAKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNSFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLAGYNNDDGSVYQPLI
                     GVMTLVVILILTAILLTFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            137845..138381
                     /gene="rbr"
                     /locus_tag="ACOIAP_000122"
     CDS             137845..138381
                     /gene="rbr"
                     /locus_tag="ACOIAP_000122"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HGZ2637048.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            138413..138802
                     /locus_tag="ACOIAP_000123"
     CDS             138413..138802
                     /locus_tag="ACOIAP_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HGZ2637049.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLSQLTEHGFIKKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLKELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            138839..139225
                     /locus_tag="ACOIAP_000124"
     CDS             138839..139225
                     /locus_tag="ACOIAP_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin family protein"
                     /protein_id="HGZ2637050.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNSVTVKVSSAIHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            139352..140794
                     /locus_tag="ACOIAP_000125"
     CDS             139352..140794
                     /locus_tag="ACOIAP_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HGZ2637051.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDENIAEDIVEDEPKLNTEKDGDLNYVSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAKSKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGKDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            141091..141213
                     /locus_tag="ACOIAP_000126"
     CDS             141091..141213
                     /locus_tag="ACOIAP_000126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637052.1"
                     /translation="MEKLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFD"
BASE COUNT        54303 a        16059 c        25932 g        44942 t
ORIGIN      
        1 aaaaactatc tactaaatta ataaaagaga acgatattat ttgcatagaa gatttacaag
       61 taaagaatat gattggaaat cataaactat ctcgcttaat ttctgatgtg tcatggtcag
      121 agtttgttcg tcaattaaaa tacaaggcta attggcatgg tagacaaatt gtaaaggtag
      181 gtaaattctt tgcaagttca caaatatgca ataaatgtgg gtataaaaac gaggaagtta
      241 agaacttaaa tataagagaa tggatttgtc ctagttgtaa tgaaactcac gatagagata
      301 taaatgcaag tatgaatata ctaaaagaag gattaagact aataacaatt caaaataaat
      361 aacttatgta agaaccgtag gaactacggg gatggcctgt ggagaattag taagacatat
      421 tttagtatgc aaaattctgt gaagcaggaa ccctgtgact ttagtcatgg gaggttcaga
      481 tactttatat atagcaaata ttatataaag taattaaagt attttaagta tattaatcag
      541 tgcataagtt aatagaaata tcctaagtat agtaaataat gtatatgtta actcaaatca
      601 accaagtata aataactaat atataaatta actcaaatat tttaaacata gtaagaaata
      661 tgtaaattta atataaatat ttgagttata gatataatta tattaaccta acaagtataa
      721 atagaggaga aaaatatgaa aaaaatagaa ttacttgcac cagtaggctc ttttgattca
      781 ttaaaagcag cagttcaaaa cggagcaaat gctgtgtatt taggtggtaa agactttagt
      841 gccagagcat ctgcaaataa ctttgataga aatgagctga ttgaggctgt taaatactct
      901 cacataaggg gagtgcaagt ctttgttact gtaaatacat tgataaaaca gtatgagata
      961 gaagattttg tagagtatgt aaaattttta tatgatatag atattgatgc tttaatagtg
     1021 caggacatag gaatggcaag acttataaaa aaactattac ctgactttga actacatgca
     1081 agcactcaaa tggtagcaca ttccttagaa gatgtgaaat accttcagag tgtaggattt
     1141 gatagagttg ttttagcaag agaattagat gttgatgaga taaaatggat ttgtgaaaat
     1201 acaactgtag atatagaagt ttttgtacat ggagctttat gtgtatgtta ctctggtcaa
     1261 tgtcttatga gtagtatgat aggcaatagg tctggaaaca gaggtagatg tgcacaacca
     1321 tgcagacaaa agtatgagtt gatagatata aatacaggag aagtagtaaa aagtaacgga
     1381 gattatctgt tgagtcctag agatttaagt actatagaag atttagataa aataattgaa
     1441 gcaggtgtat tatctttaaa aattgaaggg agaatgaaaa agccagagta tgtagctact
     1501 gtggtttcag gatatagaga agcgattaat gaatttgtag ataagaaaaa aataagtatt
     1561 tctgaggaaa taataaataa tttgtatact atatttaata gaaaatttac aaaaggatat
     1621 attttaggtg aagttggtaa ggatataatg aactctaata gacctaataa ccaaggtcta
     1681 tatattggaa aagttttaga ttataataga aagaacaaaa gacttagagt aatgctagaa
     1741 aatacgctta aaaaaggtga tggaatcaac ttaggcggag gtactattgg aaggataata
     1801 aaggatggag agataactac aatagcccat aaaggggatt tgatagaatt agattttgtt
     1861 ggagaagcaa agcgaaatca gcttatatat aaaacttctg atagcgaatt aatggataga
     1921 gtacaagcta cattccagca agataaagag ttcataaaaa ctaatataag tgcaaaagtg
     1981 agtattaaac taggtaaaaa accagaactt tttataagtg atttttgtgg aaataaatct
     2041 gtagtagaag gagacaaaat agttgaaaaa gctataaagg tggctttaag taaagaaaaa
     2101 atagaaacac aaattcaaaa gcttggaaat acgccataca agttaaaaga gatagaaatt
     2161 gacttggacg aaggtgtaag tatgcctata agtgtgttaa atcaaatgag aagagattgt
     2221 attgagcttt tagatggaga aagaataaag ataaaagata gaaagtttaa gaaaaatata
     2281 ttaaaatacc agccaaatag agtaaataaa cagaaaaaac ttaatacagt tcctaagatt
     2341 agagttaaag tcaaaaattt ggagcaatta gaagcagtat taaattatga tgtggactta
     2401 atctattatg aagatataaa tacattatca aaagctttac aaatggtctc aagtatttct
     2461 atagattcaa gtatttctac tgatttagat acttcttcgt cttcaagtat ttctaaagaa
     2521 ttaatgggtt caaatccaaa caacatagat actttgaata ataagcgttc taatacagca
     2581 gttactgaca agaaattaat ctattcagca ccaagaattg tcagaaataa agagtataag
     2641 caatttgaga tattggataa tataaaagga attaataatg ttcaaattgg taactggggc
     2701 tgtatggaat attttaagga caaagactta tatatagatt gctacttaaa tgcatttaat
     2761 agtgaaagta taaatcactt taaagaagag ggagcaagta cagtttgttt gtcacaagaa
     2821 ctaaacttaa atgaaattaa acaaacttta aaatatacag atgtagaaac tgaagcagta
     2881 atatatggat atgctcctat gatggttaca gaatactgtc ctatgggagt agttgttaga
     2941 gattgtaaaa aggataagag agttgctaaa tgtaaggaaa gtaattatgc tttaagagac
     3001 ttcacagatg caagttatag gataacacaa gatgtattct gtagaagtac aatttacaat
     3061 tcaaaggtta cttgtatgtt ggacaattta tgtgaattag atgaaattgg aatagatgta
     3121 tttaggatag attttacagt tgaagatagt gaaatggtta aaaaggttat tgaagctcac
     3181 attgaggtct tgagtaataa ttataaactt ggggaaaagg ctacagactt gtacaaaaaa
     3241 ttggatgaaa ttggaacagt tgcaggacac tactataaag gtgtagaata gatataacat
     3301 gaaaaatata catgaatata tataaaaact tgaatttatg tgtattaata tataaaaata
     3361 tcatatatat gaaaaaacag ggggattagt gaaaatgaga gaagaagctt tagaaatttt
     3421 atttaagtat ttagaaactg atagaatgag aaaacattgt tatgctgttg aagctgtcat
     3481 gagagactta gccaaaagat tagagccaga aaaagaagaa gagtgggcag tggcaggtct
     3541 tttacatgat ttggattcag atatagttgg aagaaagcca ggagaaatat gtgaaggaca
     3601 tgctacaaca acagtagaac tgcttaaaaa agaaaacttc ggtgatgaag aaatgtatag
     3661 agcaatactt ggtcatcatg atgggatggg agttacaaga actagcctaa tggaaaaagc
     3721 aatatatgca gcagacccta taactggctt tataactgct atagctttag tttatccaga
     3781 taaaaaactt actagtgtaa aaactaagtc tgtgattaaa agaatgaaag aaacgagatt
     3841 tgcttcaaat gtaaatagag atgcaatgag aagtatagaa gatataggga ttccatttga
     3901 tgaatttgca gagctttctc ttaatgcaat gaagaatata agtgatgtgc ttgaaagtgc
     3961 tgaaaataat tagtttagaa tataaagaga aagtaaggcg agatatatga aacttacaac
     4021 tatttgttat atagaaaaag atgacaagac tttgatgttg tacagaaata aaaagaaaga
     4081 tgatatacat gaaggtaagt atgttggagt tggaggaaag tttgagcaag gagagactcc
     4141 agaagaatgt gtaatcaggg aagtaaaaga agagactggt cttactctta agtctttgtc
     4201 atataaagga ttgataactt ttccaaaatt taaagatgaa gaagattggt atatgttttt
     4261 gtatttctca gatgaatttg aaggtgaatt atctgaaaaa gatttaaatg actgtaaaga
     4321 aggaaattta atttgggttg ataatgataa aatattcgat ttaaatatgt gggaaggcga
     4381 caggttgttc ttaaattggg ctaagacagg aaacattttt agtgcaaaga ttgtatataa
     4441 taatgggaaa ctaaaagatt ataatgtaag tttcttagat taattaagat tgtagttttt
     4501 agattaatta aggtgtagtt tcttagatta tttaagatag agatatcaat gcaagtatca
     4561 atctactaaa cttagccata taaatggcaa tcataagagc taggaactag cctaatagct
     4621 tggagatact gataacaata gttacttgaa caagaagcca ccacttcaaa cattaccgta
     4681 ggtagttaag tggatggtag ttcacattga ttggcataat attaagataa ataacattag
     4741 ttgagaaaaa gggttatctc aaaatagaga taagcctttt ttattgttga aatgataaaa
     4801 ataccttgat ttcacacaat aaagaatatc tcatcaacta aaaagttcac tttgtgacac
     4861 ctacttttct tatctttcat tttgaataag ttctaatata tatttctcaa ttaaagtgta
     4921 gttaagacta atatattgtt aaaaaaataa aaattgactt agacaactat ttgttttata
     4981 ctaaagtaaa ttttttaaaa ggaggaataa tttggaatga tagacataaa tttagaaaaa
     5041 tgtgtaggct gtgggatgtg cgaatcagac tgtcttgtaa atgcaataaa agttaaggat
     5101 gataaagcaa aggtgaaaaa tattctctgt attaactgtg gtcactgtat ggcaatttgt
     5161 ccaacagatg caatagaaat gcagggattt gataaaaatg aagtagtaga atacaatcgt
     5221 gaaagttttg aattagagcc cgaaaagtta ttgaatttta ttaaatttag aagaagtata
     5281 agacaatata aagatataga gatagaagaa gaaaaaataa aaaacatagt ggaagctggt
     5341 agatacacac caacaggtgg gaatagacag cctataagat acatattagt aaaagaaaaa
     5401 ctaaaagaag taaaagaact agcaatagag ggtctctata atttagcatt aaatactgat
     5461 gacaatgacc ccgtacgttc tatgtataaa aacacattta agaaaatgta caaaagatat
     5521 aaagagaacg gaaaggattc tttattttat gatgctcctc tacttatggt agttgtaggt
     5581 gatatgtctc taggtggaag tgcttatgta gatggaggat tagctgcatc taatatggaa
     5641 cttatggctt attctcaagg attaggaatt tgttataatg gattttttgt tatggcatca
     5701 aatgtagagc caaagataaa agaattgtta ggaatgagcg agaatgaagc agttataact
     5761 tcatttatac tgggttatcc agatgtgaaa tataaaagaa ctgtaaatag aaacactgct
     5821 aaatttgagg ttatatagaa tttagcctca ctacaatttg taaaattatg ggatataggg
     5881 taggtattta gcagggtaaa tttgttgtaa tagatatata aatgagttat aatttaaata
     5941 tatagtatat attaaggata tttaaatttc tgagtaaatt tatatatcct tttatatact
     6001 aatctatttt ttcatgtcta caagtttatg cagtaattta tactgtaaat cttaactata
     6061 tggaggattg tgtagtgaat ttaaaaaaat tacttttatt aattattgta attacatcta
     6121 tattcacttc ttacatattt tcttttagta tcaatgctat agctaatgat aatcgtacta
     6181 ttcggattgc ttatcctatt caaaaaggtc taactgaaat agatgagcaa ggtaactatt
     6241 atggatatac atatgaatat ttactagaaa ttgcacagta tactggatgg aattatgaat
     6301 ttgttcaagt tcctggagat ataaatgaat ctattacaaa attaatgaag atgttagaaa
     6361 atggtgaaat tgatataatg ggaggtacat tatacaatga gtcattgcaa aaaatatata
     6421 attatgcagg gaatagttat ggagtagcaa atacagtact acaagcatta tatgaaaata
     6481 cagatattga taacataatg agttctcaag gtgtaaaaaa aattcgtatt gctgtaatag
     6541 aaaattctga tactaggctt aaggagttag atgagtattg taagatgaat ttgatgtcac
     6601 ctgaattggt atactgtaaa acaaatgaag aacagttaga agcactaaag aatggtaaag
     6661 cagatgtact tcttaatgtg agtatgaatc caatagaaga tgtacgtact gtagcaaaat
     6721 tctcatcaag accgttttat ttcattactc ctaaaggtag tacagactta actcaaagac
     6781 tcaattcagc aattaataat attgaacaga aggatccata tttttcaact actttatatg
     6841 agaaatattt tacaccagag aataatcaga tgtttttatc tgatgaagaa actaactaca
     6901 ttaaagatac agaaaagtta aaggtaggag tacttttaaa taaaccacca tttcaaaata
     6961 tagataaaaa tacaggtgag ttaaaaggta tatcaattga tttgttaaat cacatatgcg
     7021 atttaacagg gctagaattt gaacttgtac ctataaaatc tcaaaaagat ttggaaaaaa
     7081 tgaccaaaaa tcatgaaatt gagattgtag caggaataat ttatgattat gaatattctc
     7141 gtaaacataa tataattatg tctcgaccat ttgtttctac tcaatatgct atgatgatta
     7201 ataacaaatt aaatgagaat agtcttgatg gaaaatgtct agctctaact agaggactta
     7261 attatgaggg tcagtttaaa gagaatattg tgtggtatga tactttagaa gagtgtatag
     7321 aagctgttaa taaaggagat gtagattata cttatggtga aggttattct atgcagtact
     7381 atatgaatca acctaagtat aaaaatgtgc gtctagttcc tcaaacttat gaagcacaga
     7441 gtatttgttt tgggataatt aaaaaagata aacaagaatt actgaatata tttaataaag
     7501 ctattacaag tatttcatca gaaaaaatgc aatcaattgt ctaccaaaat actacatata
     7561 gacaagattt ttcattactt tatattatgc aacagaatcc aattgagact atttttattg
     7621 tagctagttt gttaatttgt attattggat ttatggcatt tggtttacat actcgtacga
     7681 gtatgaacga gaagatatct ttggaactca aaaaacatac tcagttgtat gaaatgacaa
     7741 gtgaatattt ttttgagtat gattataagc aagataaatt gataatttct atgccagaaa
     7801 agggtattga gacttattat ggtttagata aaaatgatag ggaaagtgaa aataacaaca
     7861 atatagcaaa tgaaatagat aaaataagaa gagaatataa taaaaagttt tttgatgtaa
     7921 taaaatcaca agaaaatgga acgactgaaa tgtattctat tgtgtttgat gatacttttc
     7981 attggattag aattacttca aaaataattt ataatgatag aaaaatacca atgtatgtaa
     8041 tcgggaaaat atctaatatt gattatgaaa aagaggaaaa gaatagatta ttagataaag
     8101 ttcaaaggga tagtttaacc aatatttata atgcagcata tattagaaaa ctaactgcac
     8161 aaaatttatt gaatttatca actgaaaaaa atggtgcttt attgattata gatattgatt
     8221 attttaagtc aattaatgat acttatggtc acctggtagg agataaaata ctgattgacg
     8281 ttgcaaaggt acttgatgaa agttttacaa aagatgatat agtaggtcgt ttaggtggag
     8341 atgaatttag tgtttatatc aatgatataa taaataatga agaacttatc aataagtgta
     8401 atgatgtata caatcgtatt catctcatta aattgccaaa tggaaaaagt ttgtctatta
     8461 gcatgggggt agttatagca aagtgtggtc aagagtatga tgaactgtat caaatagcag
     8521 ataatgctct ttacgattct aagagagaag gaagaaatag atttaaaata gtataagaat
     8581 taattttaaa acagaataaa gcttaataat atttaaatta caataaagcc taatgataca
     8641 tgttactatc tatcattagg ctctatttct ataagttaat attgaaagta aatgttatac
     8701 taacagtagt attaacttac agagttaatt ttatatagat tacttaagac taaaatctat
     8761 ttagaatcaa aacttaaatt taatattggt tcatagattt taatatttca ataacataat
     8821 cccaaatatt agctacagaa gggatactaa catgttcatt tggagtatga acatcaaaca
     8881 tatctggtcc tatagagata gcttcagcat gaggaagttt atcaagtaat aatccacact
     8941 caagaccagc atgtagagcc ataacagtag gaactttacc agttaatctc tcataagttt
     9001 cacagcatat tttttctaat tttgagtctt ttttaaattc ccaagctggg tattgagcta
     9061 taaggtcgta attagcacct aaagcttgag ctaaaagtct tattctatca gcaatttcat
     9121 ctctaataga cataacagaa cttctaacag aagttaaaaa ttcaatagta gattctttag
     9181 tttcaattat agcgaagtta gtagaacttt caactaatcc ttctatatca agacttactg
     9241 attgaactcc atgaggagtt aagcaagaca tttgaacaac cttttcttta caatctttag
     9301 taagaacttt gtctacagaa gtttcagcta ctgagtaagt catgccaggg tcagaagtag
     9361 tgaactcatg tttaaatgca gttaaaatgt catttatttg ttttttagca gattcaacat
     9421 cagctttatt aacagctatt acacacttag cttcacgagg tatagcattg tgcttagtac
     9481 caccatcaac agaagctaat tcataatcaa catctaatac acttaatact ctagctattg
     9541 ctttgttagc atttgctctt tgtaaaacaa tttccatacc agagtgtcca cctaataatc
     9601 cagtaacttc aactaataat ccttgtttgt caccttcaac ctttttgtat tcaacaggta
     9661 aactaacaac acaagtttta ccaccagcac agctaactaa taagtatcct tcctcttcgg
     9721 agtccagatt taggatatat tgacctttaa ttaagctagg gtctaatgca tcagcaccat
     9781 tcataccatc ttcttcatta acagtaatta aaacttctag tgcaggatgc tctaaagtat
     9841 tatcttctaa tatagccata cccatagcaa cagctatacc attgtcagct cctagagtag
     9901 ttccagtagc atatatcatg tcaccatcaa ttcttaattt tatagggtct ttaagaaaat
     9961 catgttcaac attcttttct ttttcgcaaa ccatatccat atgtccttga agaactacac
    10021 ctggacaatt ttcatatcct tttgtagcag gctttcttat tattatgttt aagctttcat
    10081 cttgaatagt ttcaagacct aaatttttac caaagctaag taaaaaatca cttatgccct
    10141 tttcatttcc agaacctcta ggaatttgag atattttctc aaagttttta aaaacacttt
    10201 ctggttttaa tccttctaat acgtttccca tgactcatgt tcctccttaa tttatctata
    10261 taagtagcta ttttttttta agctaaaata aactccttta aaaatattaa agaagatttt
    10321 ttaacagatt atattacaaa taaagcatgt ttatgtataa tatatagata gctacataca
    10381 tagtataata caaaatatgt gtaaaatata tctaaaagag aaaaaatata ataattttag
    10441 aaatgaaaaa gaaataaaac ttgcagtttt tattggaaat gcttgaaaac atacattttt
    10501 aaaattaaat aaaaaagtta aaatatcgag gatggtgaat atagaaaatg aatgagaaat
    10561 cgttaagagt tctagaatac aataaaataa tagatttgtt aaagaagaaa gcctcatctt
    10621 ccttaggtct aaaatatata gaaaatttag taccaaatac tgattttgta gaagtgaaat
    10681 ctatgctaga agaaactagt gaagctcaat caattattat aaagaggggt tcagtaggct
    10741 tggaaggtat tcatgatata gaagacaagg taaagagagc ttatataggt gcttctcttg
    10801 acccaggaag tctgattatg atagcagata ctttaagagt ggctagaaga ttaagaaata
    10861 gcttatctag cagtgatgaa gaagatttta attatccaat aatacaatct ctatcaaatt
    10921 ctctatatgt atataaggac atagaagacc agatatacaa tgctataatt agtgaagtag
    10981 aaatatctga caatgcttca agtacactta gagatatcag aagaagaata gctcaaaaaa
    11041 atcaatccat taggtcaaag ctaaattcaa taataagttc aactacttat caaaaatact
    11101 tacaagatgc aataatttct ctaagaggtg atagatttgt agtacctgta aaagctgaat
    11161 ataggtcgca agtagctggt atagtgcatg accagtcatc ttctggtgcg acacttttta
    11221 tagagccaat gactatagta gagatgaaca atgaattgag acagttgaaa ctaggagagc
    11281 aagaagaaat agaaagaatt ttatcagagc tttctgctat ggttggagaa gtgagtgaag
    11341 atttaatctc aaatcaagag atacttggaa gattggactt tgcattttca aagggaaaac
    11401 tttctataca gatgagagga atagaaccaa ctttaaatga ggataaatat ttaaacataa
    11461 aaaatggaag acatccactg ttggataaaa agaaagtagt agcaaatacg atttatttag
    11521 gaagagattt ccacacattg gtgataacag gtccaaacac aggtggtaag actgttacaa
    11581 taaaaactgt aggtctattt gcacttatga cacaaagtgg acttcatata cctgctgatt
    11641 atggaagtag tatgtgtgta tatgataatg tatttgcaga tataggagat gaacagagta
    11701 ttgaacagag tctatcaaca ttttcatctc atatgacgaa tatagtatca atattacaaa
    11761 acgtaacaac agactcctta gttatatttg atgagttagg agcaggaaca gaccctgttg
    11821 aaggagctgc ccttgcgata gcagtattag aagatataaa ttctgtagga gctaaatgta
    11881 tagctaccac tcactatagt gagcttaaaa attatgctct tactaaatca ggtgtagaaa
    11941 acgcagcagt tgaatttgat atagaaactt taagcccgac atataaatta cttataggtg
    12001 ttcccggaaa atcaaatgca tttgaaattt ctagaaaact tgggctaagt gattatgtga
    12061 tttcacgtgc taaagaatat ataaatacag aaaacatagc tttagaagat gtgttacaga
    12121 atgttgaaaa aaatagaatc aaagcagtag aagatagaga agaagctgaa agattaaaag
    12181 aagagattga aagactgaaa gtagagtatg atgaaaaact tgaaaaattg gttagtcaaa
    12241 gagataagat gattgaaaaa gctaaatcag aagcattttc aattataaga caagctaaag
    12301 aagaagtaga cattataata aaagaactta gaagtcttga acaagaacga gcttcaaaag
    12361 aaaagaatcg taagatagaa gaacttagaa aagaattgac tagttctatg ggaagtcttc
    12421 agccaaccgt aaaaagtatg atagttccaa aggtatcaaa taaggagata aaagacttaa
    12481 agccaggtga agaagttaag gtaataactt taaatcaaaa tggtagtgta gtttcagtag
    12541 ataaaaagag aaaagaagca gtagtgcaaa ttggtataat gaagatgact ctacctttta
    12601 agtctttaca aaaaacacac aaagatgttt caacaaatgt aaccaaatca actagaaata
    12661 ttataaggtc aaaatctggt agtgtaaaaa atgaagttga ccttagagga ttaaacctag
    12721 aagaagctat aatggaagtc gaaaagtatc ttgatgatgc atatgtggca ggtttagagt
    12781 ctgtaacagt aatacatgga ataggtacag gagtattaaa agcagggcta caagacattt
    12841 taagaagaaa tagacatgta aaatcacaaa gaggtggtca atatggagaa ggtggagcag
    12901 gagtaacaat tgttaaatta aaataatttg tataagaata cattagtaat ttgtatgaga
    12961 atatattaat aatttgtata ggagcacatt tttatgatat tggtatctgc atgtttaata
    13021 ggaataaatt gtaaatatag tggcgataat aatgaaaatg aaaaagttaa ggaatattta
    13081 aaaggcaaag aatttacact tgtatgccca gagcagttag gtggtctatc tacaccaaga
    13141 ccacctgctg agatagttga tggaaaagta attactaaag ataataagga tgtaacagaa
    13201 aactttgtaa gaggggctaa tgaaactcta aaaatagcaa atttatatgt atgtagcgag
    13261 gcaatactaa aagagggtag cccctcttgt ggatgtaatc taatatatga tggtagtttt
    13321 tcaggtaaaa agataccagg caaaggcata acggcaagat tactggaaga agaaggaata
    13381 aacgttaaga gtgaaaaaga cttatagcaa attaacactg atgcataaaa aatgataaaa
    13441 gagtaaaaaa gtatataaag tcaacattga tgtatgaaaa atggcaaaag agtaaaaaag
    13501 tatgtaaatt caaacgggta gtataagaaa caataagata gaaaaaagtt tataaaaaac
    13561 caataatcgt gtgattaaaa attgtaatta tagtattttt aatatataca gaaaacataa
    13621 ttattaaagt gttttgcact gtaatgaaat acttgaaaaa acacgaaatt tgatttaaca
    13681 taaagagata agcacaatat aaaccaggaa caatgtagag aggagcaaca gaatgcaaga
    13741 tttcaaggtg gcaatatcaa attgccttaa agaaaaaata gaagatttat cgaaagaaga
    13801 gatagaggca cttatagaag ttccaccaaa taaggatatg ggggactatg cttttccatg
    13861 ctttaaatta gccaaagtgt ttagaaaagc tccaaacatg atagcaagtg aattggcgga
    13921 aagtatagaa ccaagtggag agataacaaa agtaatacaa ttaggcggat atgtaaattt
    13981 ctttgtaaat aaatctcaat tagcagaaac tgtaattaaa aaagttttag atgaaaaaga
    14041 aaattacggg catagtgatt ttggaaaaga caaaactgta atagttgaat attcttctcc
    14101 aaatatagca aaacctttcc atatagggca tataagaact acagttatag gtaatgcttt
    14161 atataagata tatgactcac aaggatataa gactataaga ataaatcatt taggtgacta
    14221 tggaactcag tttggtaagt taatagtggc ctttaaaaag tggggagaaa aagaagtagt
    14281 agagtctaat ccaattccag aattactaaa attatatgta agattccatg atgaagctga
    14341 acaacatcca gaaatggaag atgaagcaag agcatggttt gctaaattag aaaatggtga
    14401 tgaagaagca aaggaattat ggcaatggtt tagagatgag agtttaaaag agtttaacag
    14461 agtgtataaa cttttagata tagaatttga ttctttagca ggtgagagtt tctattctga
    14521 taaaatgaac agggttattg aactactgga agagaaacat cttttaaaag agtctaaggg
    14581 agcaagaatt gttgatttag aagagtataa aatgccacca gcacttatta ctaagaatga
    14641 tggttcaaca ttatatatga caagagattt agctgctgca atatatagaa aagaaactta
    14701 tgattttgac aagtgtatat atgtagttgg ttctcaacaa aacttacatt tccaacaatg
    14761 gtttaaggta atcgagctta tgggatatga ttgggcaaaa gacttaattc atgttggatt
    14821 tggtatggta gctcttgaag aaggaactat gtcaactaga aaaggaagag tcgtattttt
    14881 agaagatgct ttaaatcaag ctatagataa gactaaggag attatactag caaaaaaccc
    14941 aaatgccaaa aacgtagatg agatatctaa gcaagtgggt gttggggcag tagtattcca
    15001 agagttatct aatagtagaa ttaaagacta tactttctct tgggaaagaa cgcttagttt
    15061 tgatggtgag actggaccat atgttcagta tacacatgct agatgctgtg cagttttaag
    15121 aaaagcagaa gtagaagtga cttctgatat agattatagt ctattagctg atgaagatag
    15181 tgcagaagtt cttagagtta tagaatcatt caataagaat attttacttg ctttaaagaa
    15241 aaatgagcca catatagtga ctagatttat gctagattta gctcaagcgt ttaataaatt
    15301 ttatcatgac aatccaattt tagtagaaaa tttggaaata agaaaagcaa gacttgcgtt
    15361 agttttagca acaaagcaaa ctttagaaaa ttctctgaga ttgttgggaa tgcatgctcc
    15421 ggaaagaatg tagcatgaca aaatgttgaa ataaaaagaa taaaattgaa cttagtacgc
    15481 aatttgtata actgtaaaat atagggatgt cgaaaactga tgctttacat ataaaaaagt
    15541 agtatcgtat aataatatat agatagtaga ttacaatgat ttttgtacac tactatcccc
    15601 ctatatatga cagcttctta aatgggctgt ctcttttttt ttaataacaa tttatttaca
    15661 ttcaattttt cagaaaggat atatttatga atgacgaatt actaaaaaaa gtctatacat
    15721 cttcttttag tagtgcaagt agggctctta aagatttgat tataataaat acaaaatcct
    15781 taatagatga taaaacgcaa agatgtgtgt atatagacga aaatagactg agagatgaac
    15841 ttatttatta tagattttat ggagaaaaaa taggcaatat caatttttta aatattttat
    15901 taccactaat tttatcaaat actaatattc aaaaaagcga agatgaggtt attaaactaa
    15961 taaaaaaata tgttacttat tttaaaaaag aaaaactttt atttgagtat ttattaagtt
    16021 ctgtagtgta taattccatt atgcacaatc ttataaataa tagtaaaata gaatatgtcg
    16081 aattactaca gagtattaaa gacaagataa taggattttc tatagaatta gacaaatcag
    16141 atgttgtaaa gtttcagatg gcaaggatta aagcaataca attaattgat aaatatattg
    16201 atttgaaatt tgaagattat gatgaagaaa gtattttatt aaatatttta aatgttctat
    16261 atgatgtata tatggaagat agaactgtag aagatgaagg aattaatagc ataaaaaaat
    16321 ctatattatc catcctaggt gaagatagta aattaaatga agataatata gattttattt
    16381 tttctatgtc tgaatatgta gttaaattga gaaaatataa aattggagtt aaggcataca
    16441 ataaaaaaat agacccaaga agtcttataa gacttgaaga aggtaatact ataatagacc
    16501 ccatatttaa tcaaataaca gttatatcaa aaacctttaa tgataatata ttaagcataa
    16561 aaataaattc taaatcaggt atttatatat taaagtttaa aaaggtttag gtgattagag
    16621 tgtgctattt ttttctagat aatctaaaaa atctttttcc ttagtgtcag ttaaaaaaca
    16681 taattccttt actatattat tcctaaggtc aatgaaatca ctaatttgag tattttcatt
    16741 agtgtattca agagacttta taataagtag taaatctctt tttgataaag agttgataga
    16801 tactttttca attaattcca taaaaaactt cctttcctca cattacttga aattaataaa
    16861 ttaattatat agatattatt tagactttac atatactatt ttaacctata aggggtacaa
    16921 aaagacagta taatcttaaa aagaggtgag aaatatttga aaattttatt aacaacatta
    16981 aattctaagt ttattcatac aaatttggct ataagatatt taaaagaatt tgtaagagat
    17041 ttgatagaag ttgatatgaa agaatacacg ataaacaacg atttggacta tattttgaag
    17101 gatatatata aaaacgaata tgatataata ttgttttcaa catatatctg gaatgtggga
    17161 gacatagtta agctttgcga taatctaaag aaaattagac ctaatactaa aatagctttg
    17221 ggcggaccag aagttagtta tgatagttat gatgcaatga aaaagtatga ttttgtggat
    17281 tatatacttt atggagaggg agaattaatt tttagagact tagtacttca tttgcaagga
    17341 aagatggaaa taaatgatgt aaatggactt gtatatagac aaggcaatga gataatagtg
    17401 aataagccta tggaattact tcaaaatttg gatgagattc ctagtcctta tgaaaatttg
    17461 aatccaagag aatatgaaaa tagaatagtg tattatgaat catcaagagg ttgccctttt
    17521 aactgccagt actgtttatc atctactatt ccaggtctaa ggtattttag tttagagagg
    17581 ataaagagag atttaaaagc cttaatagat gcaagagtat cacagataaa gtttattgat
    17641 aggacattca atgcaaatag aaaagtggct atggaaatta tggattttct tatgaaaaat
    17701 gataatggat atacaactta tcattttgaa gttacagcgt atttgataga tgataagatg
    17761 cttgaatttt tggctgattg caaagaaggt ctttttcaat ttgaaatagg tgttcagtca
    17821 acgaatgaaa aaacacttga tgcagtagga agaagagatg attttaaaaa gttgtcccat
    17881 gttgtacaga ctgtagcatc ttatagaaat atacatcagc acttagactt aatcgcagga
    17941 ctgccttatg aagattataa gagctttgaa aattctttta atgatgtatt taatctaggt
    18001 atagaacatc tacaattagg atttttaaag atgattaaag ggacaggtat gagaaaagtt
    18061 gcagatgagc atggtttcaa atataaagat tacgctccat atgagttttt atacaataat
    18121 tatataagct atgaagaaac tttgaagcta aaggatatag aagatatact ggagagatac
    18181 tacaattcta aaaattttgt gttatctatg agatatatta taggcagatt ttataaacaa
    18241 agtcctttta aattctttga agtttttgct aagtactttg atgaaaatgg ctactttgat
    18301 ttggcacaag gaaagaatca attatataaa atattgatgg atttctataa tgaaaaaatc
    18361 aatatagata atgatgtatt caatgatata ttaaaatatg actatatatc actgggcaaa
    18421 acatcaaata taccacagtt ttttaataag ctagatgtgg atgattttaa gaatagatgc
    18481 catgtatttt tacaagataa tgataactta tcaacatatt tacctagttt tgttgataaa
    18541 ccagctaagc acataataaa atatgttcat tttgagccat ttagatttaa tgttgtggat
    18601 ttaaaaaatg atataaatac agaaataaga gaagcagaaa atgtagtctt atttgagtat
    18661 gatgataaaa aaatatttga gaaatctaaa actcataaag tagagattta agtatttggg
    18721 aggataaaat ggattttaag atagaaaaat atttgctaag aaaagcagag gaattagctt
    18781 ttataactat aaaacatggt ggagagttta aattaaaaag ctatgaagta ccaaaaggtg
    18841 gattagatgt acctataaaa aacgaggtat tagtaaaagg cataaaagaa aagactgctc
    18901 aagataagtt aaattcaatg tctatagcag atgcaatgat atatataatt gggatagata
    18961 gtaagtttaa aaacaatgca gagtatgaga agtttttaaa tgctttatca aaagatattg
    19021 atttggattt gaaagcgtat atgggatata tgtcgagaaa atactttgaa atcggtgaac
    19081 atacagattc tttaatatat ataaaagcat ttataacaat gtatccagat gatttagatg
    19141 caatgtataa ttatgcgatt gtttgtcaag agatagcaaa acagtatcaa aaagatatgg
    19201 atgataaggc aatgaatgca ttcttacttg aagcaatggc taagcttgaa gaggtaattg
    19261 atgttgatga gaactttgca ttaggttatt atcacttagg ctaccattat tataatcaag
    19321 gtcaatattt aaagactaag ttgacttggg aagaggcgtt aagactaggg ctagatgctg
    19381 atttggtagc tgagatacaa gagaatttag gcaagatgga ttttaaagtt caatatgaag
    19441 aaggatatac acttgtattc caaggtaagt ttaaagaagg attagaaaag ttacttccat
    19501 tagaagaaga acatatggat tggtggaact tgctgttcat gatagcactt ggatataagg
    19561 gtatgggcga aatagaacag gctaagatgt atcttgagaa gatattaata ataaagccta
    19621 atcaggtgga tactatagtg gaattagggc tttgtgaggc ttataagaat aatctagata
    19681 aagcaataga gtattttgaa caagcagcta agataaagga agacccagaa atactttgca
    19741 atttaggaat ggcttattta aataatggtg atattgatga tgcaacttac tatatagaaa
    19801 gagcttatga attaaatcca caagatgaaa ttacgattgc ttgtttaaga gagcttggaa
    19861 taaataaata aataaggata ttgttaggtt gtatttgatt ttattggtta aatgaggctg
    19921 tctcaaaata gagataagcc tctttttatt gctgaaatga ttaacatata tttgacttca
    19981 tacaacaaag agccattatg aagtaaaaag ttcattttga gacaccttaa ttttttatta
    20041 ttatttattt tacttcaggt gtattcaact tagatatatc caactcagat gtatccaaca
    20101 ggatagaaga aaaatctttt tgtatctgaa gtaaaaattt ttctgctgct tttgaaaata
    20161 tttgatgttt tttccatata atatttaatt tagcttctaa aggaggagat agaggtctaa
    20221 aacaaaggtt actattttct gtagtattga cgagtctatc taaacacaga gcatagccca
    20281 gaccttcttc taccaaaaga gaagcattat aaactaaatt gtatgttgca acaatgttta
    20341 gtttttcagt actgtcttga agccatttag aaattgcttt atcaacgagt gtctgtcttg
    20401 aaataataag aggtatattg cataaatctt ttggatttat cgtattttgt gatgcgaggg
    20461 tactatcttt acgcattagt aaaccccata catcagtagc aggaatttgt gtataatcat
    20521 acttctgtat atttgcaggt tcaattaaaa taccaaaatc aagaagccct ttgtccaatt
    20581 tttcagttac atcatcagca ttcccactaa aaaggtggta ttttacattg ggatattttt
    20641 gatgaaaatt atgtgcagtt ctagctataa gtctcatagc ttcagtttca ccacctccta
    20701 tatatatatc accactaata atttcattgg gattgtcaaa ctctaattca actttatcaa
    20761 ctaatgatat aatttcttct gctcttttat gtaaaagttt accctcgttt gttaaggtga
    20821 tttttctatt tcctctaacc aataatttaa ctcctaactc ttcttcaagt tctataatct
    20881 gtctagaaag tgttggttgt gttatatgta aaaaggttgc tgcaccagat atactttctt
    20941 ctcttgcaat tgctaaaaaa tatctcaata ctcttatttc cataattatc actcctcaat
    21001 attaatttgt ttattatatg attatatcaa ttattatgct ttttaagtat agttaagtat
    21061 ttaatataga tatttgatat agatagaatt atatattaca ctaaaaggag caataatatt
    21121 gcctaaaaaa taaattaaat tagttattat taaaatatta tttagaaggt acaaataaat
    21181 taaagcgcat attgaaggga tgtataaaat gaatatcaat gaatttttaa cacatgtcaa
    21241 tcaaggaaag cccgtctcta gtaaatcaga aatacataaa tttatggtta agttgagtaa
    21301 tgaagctatg agaatcacaa gtgagttaaa ctcttattat catgaaccag aagaaatcca
    21361 tagtttattt tctgagttaa ttggaaagaa agtagatgaa tcatttttta tgtttccacc
    21421 attttataca gattgtggaa aaaacattac aataggaaaa aatgttttta taaatagcag
    21481 ttgccatttt caagaccagg gtggtattga gattggagat aacactcaaa ttgggcataa
    21541 tgtggtattg gctacactta accatggcat tgcaccagaa aaacgtggta caacttatcc
    21601 ttctccaatc acaataggaa aaaatgtatg gattggtgct aatgtaactg tagttccagg
    21661 cgttactata ggagataatg caattatagc tgctggagca gttgtcacaa aagatgttgc
    21721 agaaaatact attgtaggtg gtgtccctgc aaagatttta agagttattg ataaaatcac
    21781 agaataaaat attaaacggt cttttagtta tataaattct ttataacata aaaataaatt
    21841 gagaaaaggt atattaaata tggtattatt tagttaaata tatataaggg aggggttact
    21901 tttgataaaa aaattagatg atattttaga ccaacttaaa ggaggagaga aaattgtact
    21961 ctctgtagca gcagctcatg ataaagaagt tttaatggca ataaaagatg ctgtagaaag
    22021 aaatataatt actcctatat tggttggaaa tgaaggcaaa ataagagaaa tatcaaaaga
    22081 aataggattt gatttaagtg gtatcaaaat agtggataag gatgatatca aagagtgtgc
    22141 agaaatagca gttaaattag tatcaagtaa agaagccgac tttgtaatga aaggattatt
    22201 agatacatct gtcatattaa aagaagtttt aaataaagac tatggtctta gaactgatag
    22261 tttattaagt catgttatgg tatatgagtt agaaaaatac cataaattac ttataactac
    22321 agatggaggt atgaatatag ctcctgatta tgaacaaaag gtaaagatat taaaaaattc
    22381 tataaaagct gcaaaagctt taggaatgga aactgtaaaa gttgcgtgtt tggcagctaa
    22441 agagaaagta aatcctaaga tgcaagcaac tgtagatgca gatatgttag caaaggcttg
    22501 caaagaagga gaatttggtg acaatgtaat tgtagaaggt cctctggctt ttgatttggc
    22561 tgtttcaaaa gaagctagtg agataaaagg gtttaaaagt gaagtatctg gagatgtaga
    22621 tatcatattg gttccaacaa tagaggttgg taatggaata gggaaggcct ttacatacat
    22681 ggcagactct aaatcagcag gtataattat gggtgcaaaa gctcctatag ttttagtgtc
    22741 aagagctgat tcacatgaat ctaaattata ttctattgca tatggtgcta ttgtagctaa
    22801 aaatatgaaa taggataaat attttgaaat aaataaatta aagtagaaaa aatagtaaaa
    22861 atgtctaaat taatattgta ttaaaaaaat tttatataaa aaataattat agcttcaaat
    22921 gaatatatac aaatgttcaa tttgaagcta taattaatat taaagtagga aaaataaaaa
    22981 aattcaaaaa aattagtcca aaaaatgcta ttctaagaag tttttactaa ttaagtttag
    23041 ggagcaaaaa tctgtaataa gtccaaatag tagtgaaaga taataaatac acaaacaatc
    23101 tgtaataata taaaaatgac tagaaaaatt tcaaatttga tttaaaaaaa tcaaaacata
    23161 atttaattaa actgaagtat caaaaaagta ggtttagata ttaacaaata gccaaaaata
    23221 agcgataaaa tcaacttaaa ttaagtacaa aaaataaaat ttttatgtat tatctaattt
    23281 tgttaaaaaa atatttaaat ctaaagcaaa gcactgaaaa ttagtatata atcaacttag
    23341 aaagcattta ttttattatt ttatgacatg aagtcagtca cctgggggat tttaaaaatc
    23401 aaaaaaaggg gataggaata tggatgaaaa aatgttaaca attgatttaa acagccagaa
    23461 gatgatagct aaagctagag aagaaggcgt agaaacaatg tatgatagaa aagaaggctt
    23521 taaggcacaa tgtggttttg gtcttcaagg tgtttgctgt agaatatgtg gaatggggcc
    23581 atgtagaata agccctaaga ctccaagggg gttatgtgga gcagatgagc atactatagt
    23641 aggtagaaac tttgcaagaa tggttgctgg tgggacagct gcccattcag accatgctag
    23701 agatatagca catacattag cattagctga tccaaatgga aactataaaa taagagacga
    23761 agctaagtta attactttag ctaaagaatg ggatgtagag acagaaggta gagatatcta
    23821 tgatgtagca catgaagtgg cagaaattgc attaatggaa tttggaaaac cttttgggac
    23881 attaagattt ataaaaaatg caccagaacc aagacaaaaa atatggaaag aatatgctat
    23941 agagccaaga gctatagata gagaaattgc aacaataatg cactctactc atataggatg
    24001 tactggtgat atagatagtt taatacacat gagtcttaga acttctatgg ctgatggttg
    24061 gggtggttct atgataggta ctcgtctaag cgatatctta tttggaactc cagtgccaag
    24121 aagaacagag gctaacttag cagtattaga agaaaataaa gttaatataa tattacatgg
    24181 acatgagcca gcattatcag aaatgatagt tttagcatca gaagaaccag acctagtagc
    24241 tttagctaaa gaagttggag ctgatggaat aaacttagca ggtatgtgtt gtacaggtaa
    24301 tgagattaca atgagacatg gtgtaaaaat agcaggagac ttccatcaac aagaacttgc
    24361 aataataact ggagcagttg aagctgtaat agttgatgtt caatgtatat tccctgcatt
    24421 agctagagtt gcagattgtt accatactaa atttgtaaca acttctccaa aagctaagat
    24481 aacaggttca acttatattg aatttagaga agaacaagca cttgatgatg ctaaagcaat
    24541 agttaaagaa gctattttaa actttaaaaa tagagataaa tcaaaagtac ttatacctga
    24601 attaaaatca ggagcaacag ttgggtatag tgtagaagca gtagtaaatc aattagacag
    24661 agttgtaaac tctcatatag acccagcagg aacagttaag ccattaacag actgtctaaa
    24721 agctggagta ttaagaggag cagctggtgt agttggatgt aacaatgcta aaggagtttc
    24781 aaatgaagct cacgtaacaa taatgaaaga attaatcaaa aacgacataa tagtagttac
    24841 tacaggatgt ggagcttcag cagcagctaa gtttggttta atggaagctg atgcggctga
    24901 aaaatatgca ggtaaaggtc ttgcaactgt ctgtaaatta gtaggaatcc caccagtact
    24961 acatatgggt tcttgtgttg atataagccg tatactagat ttagttggag cagcagctaa
    25021 ttacttagat atggatatgt gtgaccttcc agttgtaggt atagctccag agtggatgtc
    25081 agaaaaagca gttgctatag gatgctatgt tgtagcttct ggtatagaca cttatctagg
    25141 aataatgcct ccaatagctg gttcttcaag agcagtagat atattaacta gcgaattaaa
    25201 agataaagtt ggagcgacat ttactgtaaa tacaaatcca aaagagttag cagctacaat
    25261 aatagaagat atagagaaga aacgtgttca ctttgaagca ttagttgaag aaaaaatggc
    25321 ggaaaaagct gaagcttaag aaatagcgaa gttatagaat aaacgttttt ataagaagtt
    25381 tatggctgaa taaagttgaa taacgtaaaa tattaaagta aagaacttaa aatataatga
    25441 atatactgaa taaataaaat ataaacaata ttaaagaata ataaaactat acatgctgct
    25501 ttgaaaagct agtagggtaa atctaattgg ttcctgtaag gactagctgt agtttatttt
    25561 tagtgtataa aaatagagag tataaaaaat atttaactat aaaattaact actaaaaagc
    25621 aaatagtaat aaaaggtggt atggattatg aagatagcaa taacaggtaa aggtggagta
    25681 ggtaaaacga ctttttcttc aatgctctct aggatgtttg ctgaagacgg atacagagtt
    25741 gttgctgttg atgccgaccc tgatgctaat ttagctttag cactaggttt tccaaaagaa
    25801 gtatatgaat caatagtacc tatatcagaa atgaaaaaat tagtttcaga tagaacagct
    25861 gcttctgtag gttcatttgg aaaaatgttt aagatgaatc ctaaagtaga cgatatccct
    25921 gaaaatttct gtaaagaata caatggtgta agattactta cattgggaac agtagattct
    25981 ggtggtacag gatgtgtatg tccagagcat gttcttttga agaggctctg ctcacatcta
    26041 atactacaaa ataaagatgt agtggttatg gatatggaag cgggaattga acacttagga
    26101 agaggaacag cccaaggtgt agatgctttt atagtagttg tagaaccagg agagagaagt
    26161 ctacagactt atagaaaagt taagaaacta ggacatgata taggtgtaaa taaagtattt
    26221 gtagtgggaa ataaaattag aaataaggaa gatgaagaat ttataatcca aaacttagaa
    26281 gatggagaat ctttaggatt tatttattat aaccaagatg ttattgattc tgatagagct
    26341 aatcaatctc catatgattc tagtgaaaca acgaaagaac aaattaaggc aataaaagat
    26401 aaattaatgt cacttaaaga taaataaaat aaatagaatt tttgatttgg gattttaagt
    26461 tggttaaagg ttagacatag gcaatagata ggtaataagt aagtaattag ataaataact
    26521 agctattaag tttgaatatt ttaatagctt agtagctagt ttttaagtaa ttttacatgt
    26581 ataattatct tataaaatat aatttttaca tattaataca attttcacaa aaattatatt
    26641 ttaaatctat ttaggttgtg ggaggagatt cagttatggg atttaaatct gacattgaaa
    26701 tagctcaaga agctaagcct caagatatta gagaggttgc aaaaaaatta ggactaggtg
    26761 aagatgatgt agaactttat ggtaaataca aagcaaaagt tgactacaat ctactaaaaa
    26821 gagaaactgg taaaaaagct aagttaatac taactacagc tataaaccca actccagcag
    26881 gtgaaggaaa aactactact actataggtg ttgctgatgc atttgctaaa ttagataaaa
    26941 atgtattagt tgctttaaga gaaccatctc taggaccagt atttggtgtt aaaggtggag
    27001 cagcaggtgg aggatatgca caagttgttc ctatggaaga tataaactta cacttcacag
    27061 gagattttca tgctatagga gctgctaaca atcttttagc tgctatgctt gataaccata
    27121 ttcaccaagg aaatgcactt agaatagacc ctaagaaaat aacttggaga agatgtgtag
    27181 acatgaacga tagacaactt agaaatatcg ttgatggtat gggtaaaaaa ggtgatggag
    27241 cagttagaca agatggattc gatataactg ttgcttctga aataatggca gcgttctgtt
    27301 tggcaagtga tatatctgat ttaaaagaaa gattaggaaa tataatagtt ggatacagtt
    27361 acgaaggtga acctgtaaca gctagacaat taaaagctaa cggtgctatg gctgcattat
    27421 taaaagatgc tttaaaacca aacctagttc aaactctaga aggaacacca tcatttgtac
    27481 atggtggacc attcgcaaat atagctcatg gatgtaactc tgttatagct acaagaatgg
    27541 ctatgcactt tgcagattat gtaataactg aggctggttt cggtgctgac cttggagcag
    27601 aaaaattctt agatataaaa tgtagaatgg ctaacttaaa accagatgct gttataatag
    27661 ttgctactgt aagagcatta aaatacaatg gtggagttgc taaagcagac ttaaatgaag
    27721 aaaacctaga agctcttgaa aaaggacttc caaacttatt aaaacatgtt gaaaacataa
    27781 ctcaagtata tggattacca gcagttgttg caattaacag attcccactt gacactgaag
    27841 ctgaacttaa acttgttgaa gacaagtgta aggcattagg tgtaaatgtt gctctttctg
    27901 aagtatgggc aaaaggtgga gaaggtggaa ttgcagtagc taaagaagtt ttaagattat
    27961 tggatgaaga agaaaataac tttaaattct gctatgaaga tgatttatct ataaaagaca
    28021 agataaatgc tatagctact aagatttatg gagcagatgg tgtagattat actccagaag
    28081 ctgataagga aatagctaac ctagaaagac ttggatttac taaagttcca gtatgtatgg
    28141 ctaagactca atattcttta actgatgacc aaactaaatt aggtagacca acaggattta
    28201 gaataactgt aagacaagca acaatctcag caggagctgg atttatagtt gcacttactg
    28261 gagaaataat gaagatgcca ggattaccaa aagttccagc agcagaaaaa atagatgttg
    28321 atgaaaatgg agtaatagct ggattattct aaggaaatta atttataaat aaagagtagg
    28381 aaatatctct aaaataattt gagatatttt cctacatcct tttaaggagg attatcatga
    28441 aaatagcaga taaaacttgt gttgattttg tagaagtact atcttctaaa gaagcagtac
    28501 caggtggcgg aggagctgct gcactagtag gtgcaatagg tatggctcta ggcagtatgg
    28561 tatgtaatct tacaataggg aagaagaagt atgctgagta tgaagaaagt gtaaaagaga
    28621 tactaagtaa ggcaggaaag ttagaaaaag atttattaaa aatgatagat gatgatgcag
    28681 aatgtttctt accattatca aaagcttacg ggcttcctaa agaaaccgaa gaagaaaaaa
    28741 gaataaaagc agaaacaatg gaaaaagcat taaaagttgc ttgtgaagta ccattaaaca
    28801 tagtaagagt ttgctatgaa gctattaaat tacatgaaga tttagttgat aaaggctcaa
    28861 gacttgctat aagtgatgtt ggtgtaggag ttcagtgttt aagagctgct atacttggag
    28921 gacaattaaa tgtagttata aatataaatt ctatacaaga caaggaatat gttgataaag
    28981 taaaaacaga agtagataag ttagttgaag atggtgtaaa aatttgtgat gaagtttata
    29041 ccaaagttga aaaagctctt ggaaaataat ttttaaatga cgaaagtaga tactatgtta
    29101 ttaatatatg gtatatagaa taaattaatt taagtttgct tgtaggggag ttgtgaatgt
    29161 atggaaggaa tgtcaactaa aggacaaatt ataaaaggaa aacctgtagc tgataaaatt
    29221 agtgaggaat taataaaaga agtcgattta ctagttaaag aaggtataaa tccgaaacta
    29281 acaatagtta gagttggggc aagaagtgat gatttatctt atgaaagagg agcattaaag
    29341 agatgtcaaa acattggtat aacaacagaa gtgttagagt tagctgagga tataacacaa
    29401 gatgaatata ttgatgtatt aaagagagtt aatgatgaca aaaatgttaa tggtatatta
    29461 tgttttagac ctcttccaaa gcacttaaat gaagaagtta taaaatatgt tattgcacca
    29521 gaaaaagatg tagactgttt tagcccaata aactctgcta aggtaatgga gggagataaa
    29581 agtggatttc caccatgtac tcctacagca gtagtggaga tattaaaaca ttataatgtt
    29641 gatttaaaag gaagtaaggt aacagttctt ggaaggtcaa tggtagttgg gaagccagta
    29701 tcaatgcttt tattaagcga acatgcaact gttacaatat gtcattcaaa aactaaaaat
    29761 ctatcaagtg tagctgcaga ggctgatgta ttaatagcag ctattggtag agctaagatg
    29821 gttgatgaaa gctttgttaa ggatggggca gtagttatag acgttggtat aaatgttgat
    29881 gaagaaggaa atttatgtgg agatgttgat acaaatgcag ttttaaacaa agtatcaatg
    29941 ataactccag ttccagcggg ggttggttca gttacaacat ctatacttgc aaaacatgta
    30001 gttaaggctt gtaaattaca aaacaataaa tagatatata tgtggaaggt ttagggggga
    30061 agtagatatg ataatttctg aaaataaacc attagaagaa gtgctagggt acttgaagga
    30121 ttttgacaag ctggttttag ttggttgtaa tcaatgtgca gcaacttgta aaagtggtgg
    30181 agaagaagaa gttttaaaaa tgaaggaaac tcttgaaggt gaaggcaaaa aagtcttagg
    30241 atatgtaatg cttgaccctg cttgtaacct tttaaagtct aaaaaggatt taaaggctct
    30301 aaaagaagag actaaggaag ctgatgcagt tttatcttta gcatgtggag atggtacaca
    30361 gacaatagtt aagaatctaa aagataagcc agtttatcca gccaacaata ctttgtttat
    30421 aggggaagta caaagagttg gagaatatga agaagcctgt aaggcttgtg gagactgtga
    30481 acttggttgg acaggtggga tatgtccagt aactatgtgt gctaaaggtc ttatgaatgg
    30541 ggcttgtggt ggagctaaaa atggtaagtg tgaagtaaac gcagagaatg actgtgcttg
    30601 gataaagata tatgaaagat tagaagctat aggacaatta gataacttag tagaaataag
    30661 accaccaaaa gactattcta agcaaaataa tccaagaagt ttaagtgcaa agaaaaagaa
    30721 agaagcagca gcaaattcat aaaagttttt tttagaaggt taaaaggggg attagagatg
    30781 agcttattaa gagaaacatt agaaagtgga aaatttgcag ttactactga aatggctcct
    30841 ccaaaaggga ctgacctttc acatttaata gaatgtgcaa agccgttagt tggaagagtt
    30901 catgcagcaa atgtaacaga ttttcaatcg gcagttatga gagcaacttc tcttgctaca
    30961 tgtaaattat taaaagatgc tggattagag ccagttattc aaataacagg gagagataga
    31021 aataggatag ctatacaagg agaaatgttg tcagcaggtg tatttgggat aaacaatctg
    31081 ttggcactaa caggagacca tactagcgta ggagaccatc cacaagctaa gggagtgttt
    31141 gacttagatt ctgtggggat acttcaaact gctgagactt taatggcagg tacggatatg
    31201 gctggtaata aattaaaagg ttctccagat ttttatctag gagcatcagt aactccagaa
    31261 tattctccaa tagaagttca attattaaaa atgaaaaaga aaataaaagc aggggctaaa
    31321 tttttccaaa cacaagcact ttatgacata aatacaatga gaaagtttag agaattaaca
    31381 agggatatgg attgcaaggt attagcagga atagtacctt taaaatcacc agggatggct
    31441 aaatttatga ctgcaaatgt accaggaata tttgttccag atgaacaaat cgaaagattg
    31501 agagtagctg gaaaagaaaa ctgggtaagt gaaggaataa aaatggcagg agaacttatc
    31561 aaacaattaa aagaagaaga tttatgtgat ggtgttcata taatggcaat tggggcagaa
    31621 gagaatatac ctgctatact ggatgccgca ggtttatagt attgcaagat tgtagattat
    31681 attaggtttg ggggaattaa ggatgaagat agtagtagta ggtggtggac caggaggata
    31741 tgtagcagct ataaaagctt ctatgcttgg tgcagatgta acagttattg aaaaaagaag
    31801 agttggagga acttgcttaa acgcaggatg tataccaact aaagcacttc ttgcttcttc
    31861 aggagtattg aatactgtaa aagaagcaaa ggattttggt atagaaatag atggtacagt
    31921 taagccaaat ttcactgcca taatggaaag aaaaaacaaa gttgtaaacc aattaataag
    31981 tggtatagag ttcttatttg aaaaaagagg agtaaactta gttaatggtt ttggaaagtt
    32041 aattgataaa aacactatag aagtaactaa agatgatgga acagtagaaa ctataaaagc
    32101 agataagata atactagcaa atggttctgt tccagttgta ccaagaatgt tcccatatga
    32161 tggaaaagtt gtaataacta gtgatgaagt tcttggactt gaagagatac ctgaatctat
    32221 gttaatagta ggtggtggag ttataggatg tgagataggg cagttcttta gagccttagg
    32281 aacagaagta actatagttg agatggttga ccaaatacta ttaaatgaag ataaagatgt
    32341 agctaaacaa ctacttagac aatttaagaa agataaaatt aaggttatca caggtattgg
    32401 agtacaaact tgtgaagtag ttgatggtaa ggctgttgca actctttcta atggaaaggt
    32461 tatagaagca caatatgcat tagtatgtgt tggtagaaga cctaaccttg ataattctgg
    32521 agtagaagat ataggaattg aaatggaaag aggaaaagta gtagttaatg aacatcttga
    32581 aactaatgta gaaggtatat acgcaatagg tgatataata gatactcctt tcctagcaca
    32641 tgttgcttct aaagaaggta tcgtagcagt tgaaaatgct ttaggtaaga ctaaagtagt
    32701 agattataga gcaattccaa gatgtgttta tactgaacca gaagttgctg gtgttggtaa
    32761 aactgaaaag caacttgaag ctgaaggtgt agaatacaat gtaggtcaat ttgattttag
    32821 aggtcttgga aaagcacagg ctataggaca tttccaagga tttgtaaaag ttatagctga
    32881 taaagaaact gataagataa taggtgcagc agtagtagga cctcatgcta cagatttatt
    32941 gacagagttg tcacttgctg ttcatctagg attaacagta gaacaagtag gggatgcaat
    33001 acatccacat ccaagtttat ctgaaggact aatggaagcg cttcatgatg tacatgggga
    33061 atgtgttcat tctgtaccta aattataata gacagacaga gtacataagg ctctgtggct
    33121 agatttaagg gggaagtctt aaaatgggat acaatatagc tgttgcagga aaaggtggaa
    33181 ctggtaaaac aagtctcaca gggcttttga ttgattattt ggttaaggac aaaaagggac
    33241 cagtattagt tgtagatgct gatgccaatg ctaacataaa tgaagtattg ggtatcgaag
    33301 ttgaggcaac aataggagaa ataagagaag aagtaaatca aagagaaaag ttaggcaatg
    33361 cattccctgg tggtatgaca aaggcacaat atcttcaatt tagattaaat tctataattg
    33421 aagaaggcga aggatatgac ttattagtaa tgggtaggtc agaaggtgaa ggatgttact
    33481 gttttgtaaa tggaatactt agagaacaag taaacaaaat atctggtcat tacaaatact
    33541 tagtcatgga caacgaagct ggtatggaac atctaagtag aaaagtcact agacatgttg
    33601 atacactttt attggttagt gattgctcaa gacgtagcat acaagctgtt gctagaataa
    33661 gagatttagc tgaggaacta aagttaagtg ttggaagaat acttctaatt gtaaacaaag
    33721 ttccaaatgg ggttatgaat gatggtgtca aagaagaaat tgaaaagcat aacctagagt
    33781 taatcggtgt cgtacctatg gatgaattga tatatgaata tgattctaca ggtattcctt
    33841 tagttaactt acctgaagat tcaaaatcta aagtggctat gaaagaaatt tttgctaaat
    33901 tagaattaaa ataggtttaa gggggaaaaa aatatgacat ttaaaatgtc tactcaaaaa
    33961 tattctggaa aaatatcaga agttgaagta ggaatagggg aaaaagcaat taaattaggt
    34021 ggggaaaatg tattaccttt ttatagtttt gatggagaag taggtaatcc tccaaaaata
    34081 ggtatacaaa tatcagacgt ttatcctgaa agctggactg attcatataa ggagttatac
    34141 aaagatgtag ctaaatgtcc agtagaatgg gctaaatatg ttgaagctaa cacacaagca
    34201 gattttattt gtttaaaatt tgatggttct gacccaaatg gattagataa gtcagttgat
    34261 gaatgtgctg atgtagctaa ggcagtaatt gaagcaataa aattacctct agttgtagct
    34321 ggttcaggaa atcatgaaaa agatggtaaa ttgtttgaaa aattagctca aacattggat
    34381 ggacataact gcttatttat gtcagcagta gaagataact ataagggcgt aggagcatca
    34441 gctggtatgg cttattcaca taaagtaggg gctgaatctt ctgttgatat aaacctagct
    34501 aaacaattaa acgtattgtt aactcaatta ggtgttaaag gtgaaaatat agttatgaat
    34561 gttggatgtt cagcagttgg ttatggatat gagtatgttg catctacaat ggatagaatt
    34621 agacttgcag catttggtca aaatgataag acattacaaa tgcctatcat aacaccagta
    34681 gcttttgaag taggtcatgt taaagaagct atagctccaa tagaagatga gccagattgg
    34741 ggttgtccag aagaaagaac tatagcaatg gaagtttcaa ctgcagcaag tgttttagta
    34801 ggtggttcaa acgcagttat acttcgtcat ccaaaatcaa tagaaactat aaaagaattg
    34861 gttaacgcat tagcttaatt aaattgttaa ggttaggggg aaaaaataat ggcattaaaa
    34921 gctttagata tatttaaatt aacaccaaag aaaaactgta aggattgtgg attcccaact
    34981 tgtatggctt tctctatgaa ggttgcttca ggagctgtag aagtaggtaa atgcccacat
    35041 atgtctgatg acgctatagc aaaattatca gaggctactg cacctttaat gaaagcttta
    35101 aaagttggtg ctggtgcatc tgagtatgaa ctaggtggag aaacagtatt atttagacat
    35161 gaaaaaacat tagtaagtag aaatagatat gcagtttcat tctgtacttg tatgagtgat
    35221 gaagcagtag attctaaaat agctaacatg aaaaaagttg actatgtaag aattggtgaa
    35281 caaatgaaag ttgaaatggc tgttttagag tattgtggag ataaagatgc gtatttaaaa
    35341 ttaatagata aaataaaagg cagtggatta gaagtagctt atattttagc ttgtgatgat
    35401 gcacaagtag ttaaagaagc tgttgaagta ttaaaagatg ctagaccaat ggtgtatgga
    35461 gcaactaaag agaactacaa agatatgata gaagtagtta aaggagcaag tttaccacta
    35521 ggtgtaaaag ccggtagcct agaagaatta tatgaaacag ttgagttaat tcaagctgct
    35581 ggatataaag aattagtatt agatgtaaca ggagaaaaca taaaagatac ttacactaat
    35641 gctatacaag ttagaagaat agctttaaaa gagcaagata gaacatttgg atatccttca
    35701 atagtatttg caaatagatt atctaattca aaccctatga tggaagttgc tttatcatca
    35761 atattcacta taaaatacgg ttctataata gtaatagatg atattagtta tgctaaggca
    35821 ttaccattat ttgcactaag acaaaatata tacactgacc cacaaagacc aatgagagtc
    35881 gaaccaaaga tttatccaat caacaaccca gatgaaaatt ctccagtatt agttactgtt
    35941 gactttgcat tgacttactt catagttgct ggggacatag aaagatcaaa agttccagta
    36001 tggttagtaa taccagatgc aggtggatat tcagttctta catcttgggc tgctggtaaa
    36061 tttggtggaa actcaatttc tgctttcatc aaagaaagta aagtagaaga agtaactaat
    36121 tgtaaagacc ttatcattcc aggaaaagtt gcagtactta aaggtgatat agaagataac
    36181 ttaccaggat ggaatgtagt tataggacca gaagaatcta tggaattacc taagttctta
    36241 aaaggatacc aagaaaaagc atgccaaaca aactaataaa atattaacta actattaata
    36301 ttaaatttaa agggggacat tataaatgga aaaatttatg attataggtg aaagaataca
    36361 ctgtatatca ccttcaataa gaaaagcatt agcagaaaga gacccagctc caatcttaaa
    36421 aagagcaaaa gaacaattag aggcaggagc acactatata gattttaata taggacctgc
    36481 tgaaagagat ggcgaagaaa taatgacatg gggaatcaaa ttacttcaat cagagttcaa
    36541 caatgttcct atagcattag atacagctaa taaaaaagct atcgaagctg gacttaaagt
    36601 ttacgataga actaatgcaa aaccaataat aaactctgct gatgctggtt caagatttga
    36661 tttaatagat atagcagctg aatatgaagc aatggttata ggtttatgtg caaaagaagg
    36721 tatcccaaga gataatgatg agcgtatggc ttactgccaa gaaatattag aaaaaggctt
    36781 aatgttagga atggagccaa ctgatatact attcgaccca ttatgcttag ttataaaagg
    36841 tatgcaagaa aaacaagtag aagttttaga agctataaaa atgatgactg agatgggact
    36901 tttaactaca ggaggattat ctaatgtatc taatggatgt cctaagcatg ttagacctgt
    36961 tttagatagt gcattcttag caatggcaat ggccaatgga tttagttcag ctataatgaa
    37021 tccatgtgac ccagaattaa tgaaaactgt aaaatcttgt gacataatca acggggcatc
    37081 tttatatgca gactctttct tagagctaaa tgaaggtgga tttgctttct agggttttta
    37141 gggtatagtt aataaaaaat aggtgtaaat attaaagggg gaaatagaat gaatctatat
    37201 aatataatct ttacagggtc agaacaagct ttaggtgcgg ctcaagctat gctagctgaa
    37261 gctatagaaa aaaatggaaa agaacataaa gttgctttcc ctgatacagc atattcatta
    37321 ccttgtatat atgctgcaac aggacaaaag atgaacactt taggggactt agaaggtgct
    37381 ttagaagtag taaaatcttt aataaataga actcatttac tagaacatgc tttcaatgct
    37441 ggcttagcta cagctttagc tgcagaagta attgaagcat taaaatattc aactatggat
    37501 gctccatata gtgagccatg tgcaggtcat ataactgacc ctataatcag atcacttggt
    37561 gtaccactag ttacaggaga tatacctggt gttgcagttg ttcttggtga gtgtccagat
    37621 gctgaatcag cagcaaaagt tataaaagat tatcaatcta aaggtttgct aactttctta
    37681 gttggtaaag ttatagacca agctatagaa gctggagtaa aaatgggtct tgaactaaga
    37741 gttatacctc taggatatga tgtaacttct gttattcacg ttgtatctgt tgcagtaaga
    37801 gcagcattaa tattcggagg attaactcct ggtgatttaa acggattatt agagtacaca
    37861 gctaatagag ttcctgcatt tgttaatgca tttggaccat taagtgaatt agttgtatct
    37921 gcaggtgctg gagcaatagc tttaggattc ccagttataa ctgaccaaac agttcttgaa
    37981 gttccaatga acctattaac tcaaaaagat tacgataaga tagtagctac ttcattagaa
    38041 gctagaggaa taaaaataaa agttactgaa atacctatcc cagtttcatt tgcggcagca
    38101 tttgaaggtg agagaattag aaagagcgat atgtttgctg agtttggtgg aaacagaaca
    38161 gaagcatggg agcttgttgt taagaaagaa gcaacagaag ttgaagacca taagatagaa
    38221 ataataggac caaatataga tgaagttgat gcagatggtg tattaagatt accacttgct
    38281 gtaatagtta aaatagctgg taaaaatatg caagaagatt tcgagccagt tcttgaaaga
    38341 cgtttccact acttcttaaa ctatatagaa ggtgtaatgc acgttggaca aagagatatg
    38401 gcttgggtaa gaatctctaa agatgcattt gataaaggct ttagacttga gcatatagga
    38461 gaagttttat atgctaagat gttagatgaa tttgaatcag ttgttgataa gtgtgaaata
    38521 actataatta cagatgctga aaaagtttct gaattaaaag gtgaagcaat agctaagtac
    38581 aatgctagag atgaaagatt ggcttcatta gttgatgaaa gtgttgatac tttctattct
    38641 tgtaacttat gtcaatcatt tgcaccagct cacgtttgtg ttgttactcc tgaaagactt
    38701 ggtctttgtg gagcagttag ctggttagat gctaaggcta ctaaagaatt agacccaaca
    38761 ggtccttgtc aaccaataga aaaaggcgag tgcttagatg atagaacggg tgtatggaac
    38821 tcagtaaatg aaactgtaaa ccaaatatct caaggtgcag ttgaatctgt tacactatac
    38881 tctatattag aagacccaat gacttcttgt ggatgcttcg aatgtatctg tggtataatg
    38941 ccagaagcaa atggatttgt tgtagttaac agagaatttg caagtgttac tccagttggt
    39001 atgactttcg gagaacttgc ttctatgaca ggtggaggag ttcaaactcc aggatttatg
    39061 ggacacggaa gacatttcat atcttctaaa aaattcgctt atgcagaagg tggaccagaa
    39121 agaatagttt ggatgccaaa agaattaaaa gattatgtag ctgataaatt aaatgctaca
    39181 gttaaagaaa tgactggaat agaaaacttc tgtgatatgg tttgtgatga aactatagca
    39241 gacgattctg aaggagtatt agctttctta gaagaaaaag gtcatccagc attagctatg
    39301 gaaagtgtaa tgtaattgat ggaaaattta aaataatatg atataatatt aatatgattt
    39361 aagtaattta atcaataata taatattggg ggtctatcga aatgaaatta ttaccagaat
    39421 taaaatactc taaggatcat gagtgggtaa aagtaattga tggagatgtt gtatatatag
    39481 gtataacaga ctatgctcaa gatcaattgg gagaaatatt gtttgttgaa acaccagaag
    39541 tagaagatac tgtaactaag ggagtagatt ttggagtagt tgagtcttct aaagtagctt
    39601 ctgatttaat atctcctgtt aatggtgagg tattggaagt taatgaaaaa ttagaagatg
    39661 agccagaatg tataaatgaa gacccatatg aaaactggat attaaaagta aaactagctg
    39721 atgtggctga acttgatacg ttattaagtg ataaagaata cgaggctgga ttagaataat
    39781 taaagattag gatattatta taattgggga aagtatagta aaatttgagt gcacgcaaat
    39841 ttagctatac tttcctttta tcatatacag aacaaattgg gagggataac atgataaaag
    39901 tgagttttac accaaacaat aaagaggttt attgtaatga gggggatata ttactagagg
    39961 ttgcaagaaa tgcagatata ttcatagatg ctccctgtaa tggaaacgtg tcttgtggta
    40021 agtgtaaagt aaaattattg aatggaaaag ttgatacaga aaaaacaaga catataacag
    40081 atgatgagtg ggagcaaggt tatatactag cttgttgtac aaaggtaata tcagatatag
    40141 aaattgaagt tccttctaaa gtatcatctt ctatgcatgg tatgaagata gaaggtagta
    40201 ataaaaaaga ggatagagaa atatttgaaa gagctaaaaa aataattgaa gaacataacc
    40261 ttcaatttaa aacaaatata aaaaagaaat atatagaaat ggaagaacca aatttagatg
    40321 ataatataag cgacgtagat agattggaaa gatatgttag aaataactta gggtacaatg
    40381 aaatagattt tagattggat atacttagaa agatgccaac catatttaga aagagtgatt
    40441 ttaaggttac aataacatat gttcaaaaac aaaagaaact tacaatcata aatatagaag
    40501 aaggaaataa agaaaattcc ttatatggag ttgcaataga tattggtaca acttcagtag
    40561 ttgtttgctt agtagaccta tactcaaaag aggtagtaga taaagcatct tctggaaatg
    40621 cacagataaa atacggagca gatgttataa atagaattat atattcaact aagaaaaatg
    40681 gattagagac acttcacaaa gccatagttg aggaaactat aaatccactg ctaaaaacaa
    40741 tatatgagag aaatggaata gataaggagg atgtagttac attagtggct gctgggaata
    40801 caactatgac aagtttattc ttgggtgtat atacagactt cttaagacaa gagccttaca
    40861 taccaccatt tttaaaatct ccaaaactta tgggagaaaa tgttggtctt tttgtaaatg
    40921 acagtgcata tgtgtactta gctccatctg ttgcaagtta tgtaggagga gatataacag
    40981 caggtgtatt atcagcaggt atatggtcaa gtgaagaaaa tgttttattt atagatttag
    41041 gaactaatgg agagatagta tttggaaata aagattatat gatgagttgt gcatgttcag
    41101 caggtcctgc ctttgaaggt ggaggtataa gctgtggaat gagggcatca gcaggagcaa
    41161 tagagaaagt aattattgat aaagaaactt tagagccaac attaaaaatt atagatgaat
    41221 gtgcaccagt tggtatatgt ggttctggta taattgattt aatctgtcaa atgattacta
    41281 aaggtgtaat agatagaaga ggtaaaatat acagggattt agataacaag agagttagat
    41341 ttaatgagca tgagatagga gagtatgtat tagcatttaa agaagaattt gatttagaaa
    41401 atgatatagt agtcaatgaa gttgacatag ataatttcat tagagctaaa ggagctatat
    41461 attcaggtgc atacactctt gtagacagtt taggtatgga ttttagtata ttagataggg
    41521 tttatatagc aggtggtata ggaaataacc tagacataga aaactcaata attataggtt
    41581 tacttcctga tattgataga gaaaaattta cttatatagg aaatagttca cttgttggtt
    41641 cttatttagc tctcataagt aaagatgcaa aaaataaact tgaagaaata ggtaatcaaa
    41701 taacttatgt tgaacttagt gtatatccaa gctatatgga tgaatttatt tctgcatgtt
    41761 tcttaccaca tacgaatata gaacagtttc caacagcaaa gaaattatta gaagagtaaa
    41821 atgaacttaa gaaggaataa actatgaata aaaatctatc tgaaaaagtg aaagtagcat
    41881 ttgatattaa attaaaaaat tttggaaata aaatagagtt tgcttatcct aatcagacac
    41941 tagctcttag taccacaaac aataaatgta gtttaaaatg tgctcattgc aatggtcact
    42001 atttaaacaa tatggtacca atagaggatt atgaggaaaa agtacaatca agaaatataa
    42061 ctagtttttt attaagtggt ggatgtagct atgatggtga tgtcccaatg agtactcata
    42121 ttcagactat taaaagatta aaggagcaag gttacagatt gaatgctcat ttaggactta
    42181 tggataaaga gagcattata gaattgtgta agtatttaga tatagtttct tttgatttag
    42241 tatttgataa agaaacaata agagaagttt ataagatgga aaagagcaaa gatgattata
    42301 tagaagttta taatacaata agagaaaata cagaagtagc accacatata tgtattggtt
    42361 taaaaggagg acagataaaa ggtgaatatg aaattatcga atacctacag aaaaatcctc
    42421 ctaataaact tacatttata atccttattc caacaaaagg aactgagtat gaaaatgtag
    42481 aacctcctga attagaaagg gtagcagata ttttatgtga agctagaatt aatttaccat
    42541 atactgaaat taatctaggg tgtatgagac caagaggagt gtatagaaaa gagctagacc
    42601 agttatctat aatgtgtgga gtcaataaaa tagtattacc atcaaggtct gccaagaata
    42661 aagctataga aatgaatatg acaataactg aatgtaagga gtgttgcgtt ttatgattag
    42721 actatcagtt ggaacagcaa tagaacttgg aatattaaac aaaaaaagcg atatacctcc
    42781 tactacagca tatataatga ttggagaaaa atgtataaat aaatgtagtt tttgctccca
    42841 atcaatagaa agtagtacta gaaaagataa attgtccaga gtagtttggc cagagttttc
    42901 aaaagaggaa atattagatg cgttaaaagc ttataaagga aaaaatataa agagaatatg
    42961 tattcaatca atggcaagtg aagaagcaca caactctgtt ttagatttta taaactatat
    43021 aagtggcaag atagacatgc caatttcact atctgcaaaa ttagaaaatg atgaacagat
    43081 aaataagttt ttttcagcag gagtagataa aataggaata gcaatagatg cagcaaataa
    43141 agaactatat gaaaaaataa aaggcaataa ttataatgaa aagttaaaat ttataactga
    43201 aatgtcaaaa tcatatccca ataaaataag tacacatata atagttggta tgggtgaaag
    43261 tcatgaagat atatacaatt tatatactta tttaaaggga aatgacataa cgattagttt
    43321 atttgcattt actccagtta gaggaactaa aatggaaaag ataaatcaac caaatataga
    43381 aagctataga agggtacagt taatgtctta tatgataaat aaaggttatt caaaagagta
    43441 ttttacgttt aaaaatggat acttagatag cataaagctt gacaatgata ttgtaaaaga
    43501 cataaacaaa ggttatcctt ttgaaataag aggttgtaag gattgtaata gaccatacta
    43561 taatgaaaga ccaggtagta ctatatataa ctattcaaga cctttaaatc aaagtgagat
    43621 agatttagca ataagagaaa taaatctata gaggatttct aggatatatt tatactaaaa
    43681 atgggggcgt aataatcatg aatcagtgga gagttataca taataaatca tatgaaggag
    43741 caatgaatat ggcaattgat gaagctatat ttactgcata taagaaggga cataataagc
    43801 caactcttag attttataca tgggaaccag cttgtctgag tataggatat tttcagaaat
    43861 tggaagatga gatagatttg gacaagtgta gatgtatgaa tatagactat actagaagaa
    43921 ttacaggtgg aagggctgta ttacatgata atgagctaac ttatagtata attataggag
    43981 aagataatcc tttaattgat aagagcatca acctgtctta tagatatata agtgaaggtc
    44041 tagttaaagg actgaattta agtggtatag aaacagataa tttgaataga ggcgagagaa
    44101 taagtaggga aaatttatca gctgcgtgtt tcaatgcaca tgcatcatat gaagttacca
    44161 ttaataataa gaaagtaatt ggaagtgctc aaagcagaaa agatggtgtt ttattacaac
    44221 atggttcaat aatactggat tttgatgtag aaaaattgtt taaattaata aaaacgaaga
    44281 caccagaact gaaagaaagg gctatgaaat ttacagctaa aaaagcaagt ggaatagaaa
    44341 atgaaattgg cagaaaaata gacatagata ttctacaaaa aaacatagta aagggattag
    44401 ctgaacaatt taatgttgag tttgtggagg gtgatttaac tgattacgag aagcaattag
    44461 ctaaagaact atatgaaaaa tacaagaatg aagagtataa taaaaagcgt taactttaat
    44521 tgactttata taaattaaag tgctatactt aaggtataat aatatacaaa aactgaaatc
    44581 atgaaggttt ctttggtgta ttgaaatacc taaggaaatc tttttttgat ttttaataaa
    44641 aatcatatta ggaggagatt tatatgtgtg aatcatcagc tttcatttgt aaaagtaata
    44701 atgagttaga aaaggttatg gaaaatgtgg ttaatataga cccttgtgat ggaaagattt
    44761 atttaacgga tttattagga gagcaaaaga taatagatgg gataattaaa gaaataagat
    44821 tgatggacca taagataata atacaagaaa attaattaat aggggaattt catatgataa
    44881 tagcagtgat agatggaatg ggtggaggta ttggagccca gatagtttct tctttgagag
    44941 aagagttacc tacatatgta gaaatttatg cactagggac taattctata gcaactagtt
    45001 ctatgatgaa ggctcatgct aataaaggag ctacagggga aaatgctata gtagtatcag
    45061 ctaaaaaagc aaatataata gttgcaccta tttctgtaat aatacctaat tctatgatgg
    45121 gagaagttac ttgtaatata agtgaagcta ttgcagatag tgaggcactt aagatacttt
    45181 tacctattat gccagaaaat gtggagttag ttggattaga aggtaaacca ttagcactac
    45241 ttgtaaaaga ttctgtaaat cttataaaaa aagagtttaa tataaaataa cagggggaat
    45301 aactaatgat ttttgataga gagattgtaa gatatcatca tggacatcat gaccatgacc
    45361 attgccacga gcatactcat ggagatatat gtcatgaaca tccacatgac catgctcatg
    45421 accatgacca cgaacatagt catgaggaat catcagagtc taaggatgaa aaaactttaa
    45481 aaatactttt ggtacattgg ataaatcata atgaaactca tgaagaagga tttagagagt
    45541 gggttgaaaa ggctagagct attggaaaag aagaaacagc aaagagtatt gaaaaggcta
    45601 tagagtatat ggaagaagct aataaaatgt tgttagaggc taaaaaacat atgtaaatat
    45661 aattaatcgc ttatacgttt gatataagcg atttttatgt tttttgatgc ttaattatta
    45721 aatttcttat ctaatggatt gtctcaaaat agatataagc ctctctttca ttgttgaaat
    45781 gataaaaata tactttaaag gctgtttaaa attgctccaa gattagatat aataagaatt
    45841 agtataatta aaaatattgt tttgaagtta aaaaatttat gtatttatat aagatttttt
    45901 ctttaaaaaa ggagtgaatt atttatgaaa gatggtcata tacattcacc ttattgtcct
    45961 catgggagta aggatgattt tgaaaaatac gtacaaagag caatggatat tggaataaca
    46021 gaaatgacct ttacggaaca ttttccatat gcaaatggat ttagagaccc tgctcctgaa
    46081 aatgatagtt gtatgagtat tgaagatttg ccaaagtatt ttaatgatgt caagaagttg
    46141 aaagaaaagt atgagggtaa aatcaagata aatgttgggt cagaagtgga ttttatagaa
    46201 ggatacgaag aagggataaa ggcgaattta aataaatatg gagaagaatt agaggattct
    46261 cttttatcag tacatataat taagattgat gatgattatt attgtgtaga ttacagtata
    46321 gaagaatttc aaaatttaat cgacaagcta ggtagtattg aagctgttta taataagtat
    46381 tatgaaacac tgataaaagc tgtaaattca gatttaggta tacataaacc aaaaagaata
    46441 ggtcatttaa atttagttag aaagtttaat caggtatttc catacgatta taaaggaaat
    46501 accattcttg aagatttaat aaagttaatt aaagaaaaag gttatgaact tgattacaat
    46561 gtttctggaa atagaaaaga gtactgcaaa gagccttata tagatggata cttattagag
    46621 ttggtaaaaa aatacgatat tccattagtt ttaggctctg attctcactg tgcagaggaa
    46681 ataaataaat acgatattgt ttagatatat ttgcataaaa gactgtagat aagtttgaat
    46741 aaaataaatt tatctacagt cttttgtaaa tttatatgat taaaaatagt aatagaactt
    46801 aaataaaata ataatgagtt ctaagtaaaa taacaataga atctaagtaa aataataata
    46861 ataaaattca atagaataat aggatttaga attaatctat cttatttata taaacattct
    46921 tatataagat tgtagataag cttgtattta cacaaatcta tagatattct ctattatatt
    46981 gacttagtaa ttataagtac tattttgcat ttaaagttat tatttcataa gtttatcgtt
    47041 ttccattatt acagggtcag gcaattcaat ttcactttct gacatcttca atctattaaa
    47101 catataattt tttacatctt tcttgttttt aaatttagta acttgataag gtgatgtagg
    47161 gccgtatttt tctacaaata gaatgccatt tttagtttta atacatatgc ctgtatgacc
    47221 tataaatacg tttttagttt ctggataacg aagaaatcca tttataatag atatattttt
    47281 attattttta aaagatattt ttcttttttt ccactcattt tttatttgtt ctgcaatttt
    47341 agatatatca cttgtatctt tagctggtat tgcagaaaag aagttgataa atttttctac
    47401 atctttggtg ctaaatttag catctttatt attcattata gtgtccaagt cgacatttaa
    47461 atcaatagag tctccagtaa atttattatt tgaatttata aaatctttaa aaagtctaaa
    47521 agcagttatt ctacaattta catccatata atcagggaat tttttcatcc aattatcttg
    47581 caatttttct aggttatatg gaacttgttt tgcattgatt gaagaatatc cagatttaga
    47641 tatatttata ttattttgaa gtattttaac ttgcaattta ttataattgt tgactgcttt
    47701 aataaatgta tctatgtctt tttcattaat tttattttct tttagaattt cctctacact
    47761 attttgagtt cttttatcta tcatattaga atatatcaat ttattattat atttaatatt
    47821 tgaatatgca aatatcgtaa gtacacttga tagtactaag acaagagata atataattat
    47881 taatcttttt ttcattttga gttctccttt ttaaatttat tgtgtcgaca tatttatagt
    47941 atatagtacc tttaaattta ccttcaatat gtttttaatt acaaaactgt tgtaaaaaat
    48001 ataacgttat ttaaaacttt tttttaatat gtaaaaatat atactgatag ggggtatttg
    48061 tttttagaat attcagtaaa atagttttga gatattatat atattttgta tgttaaaaat
    48121 aaagaaatta ttgttaaaac agataaagac cttaaatttt ttatcgtaag cttttaagta
    48181 aataagacgt attgaactaa ttaaaaattt ttattttgta aaaatgagta tttatttata
    48241 tggataaatt tgattttaaa tctatcaata tagataaaat ctcattattt aacttcaact
    48301 attcctcaaa aaagtaactt ttaaggaata gttgaaacaa aaagtttggt tacataatag
    48361 taattttagt tacaagaatg aaactgtaat acttaggatt ttctttatat aatttcattg
    48421 agaacattta acttaggagg taagatatga aagtaaaaaa atttaaaagt ggtatagtaa
    48481 tggcattaac agtaatggta attggagcat cattgacaaa tgtatcagct atggaattaa
    48541 ataagagtaa ggagtttgaa actaaataca atgaaatgaa gagggatttt caagaggaat
    48601 atggaaaaga agacaaattt aatataacat tggatgatga atttacaaaa gaagaagtaa
    48661 atggagctaa agggattata aagacaacta ataaagtgaa taatgaggtt gtagtattaa
    48721 attattttga tgaaatgaaa tctgggattg aatttgagtt gaagccaaaa gcagaaaaaa
    48781 atgtaatttt gagagaggaa tttcaacaag gttatggaaa ggaagataaa ttcaaagttg
    48841 tgttagatga tgaatttaca aaagaagagg taaatggagc taagggaatt ataaagacta
    48901 cagataaaga aacaggtgag gttatcgtat ataattactt tgatgagctt gaaaaataat
    48961 gtgtaaagat tactttgatt gaatgcaaag gtaattgttt tgagaatatg aaatgactga
    49021 ataaaaaacg attgtatcaa aaacaaataa taattgaatg taagtataat tgtatcaaaa
    49081 atataaaata aattaaaaga aaaagattat actgaaggaa aaagatttga aataggggtg
    49141 aactttacat attatagttc acccttatac aaaaatataa aatataattt attataggaa
    49201 aatttaaaaa aatcagatta tttaatttat actgatatgt tgtaggattt tacaaacaaa
    49261 ctgttatata acttttttta tctccaatct tgattttaat atatctaaga atttataaca
    49321 atcttctgga tatatttctc ccatatttgc aacttggaat atgttagcat ctaggaattt
    49381 gccttttcct ggatatacaa catagccact ttccctttct agccctaata taaactcatc
    49441 tacattgatt tctttaggta gaaatacaga tgttactgta ttagacatat acttatctgg
    49501 aagtaaaaat gttagaccca attcttccat gccattcctt aaaatagcag aacattcttt
    49561 gtatctttct attttactgt catcttccaa aaactcagtt aaagcttcat taagggcaaa
    49621 tattaaagta acattaggtg tatttggtgt ttgagaagat gatttagcaa ctttatagtg
    49681 tttataaaga ttaagataca cattcttaca ttgattttct ttaatatctt gtaaaatact
    49741 ctctttagca caaaggtatg cagaacctgg aaatgctcca agagctttac caccaacacc
    49801 tgttattata tctatattaa actcttccac atcaatatat tcacctgctg atgcacttat
    49861 tgcatctaca aaaaatattt tgttatactt cttagcaagt tttcctagtt caggaaccgg
    49921 atttatcatt cctgaactag tttcatggaa caccatagca attactttta tatcagaatg
    49981 ttcaattata tatttttcta aaatgtttag gtctgggtat tctgcccatt caaaattagg
    50041 cttatatgtt tttacattat aagtagataa tatttcttct agtctttctc caaaaacacc
    50101 attactaact agcagaactg catcttcttt atcaaagata gaagatagta cacattcatt
    50161 tacagatgtt ccagagccag atacaattaa tgagtagtaa ttagaagttg cattatatag
    50221 tttattgatt ttttgttgtg tatctttgaa taaatccata aactcatttc ctctatggca
    50281 tatatcatag tgaagaagtg aatttctgac tttatctgta accattactg gtccaggact
    50341 gaatagatat gtttttttca ttgtaaagcc tccttaaaaa gttaaattta aatttttgaa
    50401 tgactgatta tgtgtaaata ttagaatatt atgtgttatt ttaactagat tatagaataa
    50461 aataataaat attgcaataa tattttaata aaaatacttt tttaatcatg ttaattaaaa
    50521 ataacaaaaa atattgtaat gaatattgca taaatccaca tgatgatata aaatataaat
    50581 aacttgaata gattatatat tcaaaaaata aaaaagaatt tattaattct gaaaataaag
    50641 ggggacattt aaagtgaaat atgtattagc aattgaccaa ggaacaacag gaacaagagc
    50701 agtattgata aacgaaaaat cagagtttgt ttttagcgat tatatggaac atactcaaat
    50761 atatccacaa tctggatatg tcgaacatga ccctatagaa atttggaata atacaaaaac
    50821 tgtgagtaat aatgtattac aacaggcttt tgaaaatgga atcaatgaaa gcgatataaa
    50881 aggaattggt atagataatc aaggtgaaac agtaatgtta tgggataaaa atacaggtaa
    50941 accactttac aatgctattg tatggcagtg caggagaact tatgattatg tggaaaattt
    51001 aaagaatata ccaggtttag aaaataagat aatagataag actgggttaa ttatagaccc
    51061 atatttctca ggcacaaaaa ttaaatgggt aatagataat gtaaaaggtg taaaagaaaa
    51121 aattaaaaat ggagaagtac ttgcaggaac attagatagt tggttaatat ggaaaatgac
    51181 aggaggaaaa tcttttttaa ctgatgtatc tacagcagca agaacaatgc tttttaatat
    51241 aagagatatg gattgggata aagagttgct tgacattata ggagtgccta gaagtatttt
    51301 agcagatata atgcctacaa gtggtgattt tggaactaca gataaggagg cattttgtgg
    51361 ggtttctata aaaattactg cttcaatggt agaccaacca gcagctttat ttggcaatgg
    51421 atgttttgaa ccaggaatgg ttaaaaatac ttatggtaca ggatgttttc tatatatgaa
    51481 tataggtgag gaactaaata tagcaggtaa tggcattttg acaactgttg cttggaaaat
    51541 aggagataaa gttacatatg cttatgatgg tggagtgtat atagcaggtg ctgcaataca
    51601 atggcttaga gatggaattg gagttataaa aaattattca gaaactgatg acatggcaaa
    51661 ttccatatca agtactggag gtgtatattt tgtaccagca tttgcaggta tagcagcacc
    51721 ttattgggac caatatgcta gaggtacaat ggttgggata acaggaagta ctaaaaaaga
    51781 gcatatagta agagcgactc ttgagtctgt tgcacttcaa gtcaaggatg ttgttgattc
    51841 tatgaactta gcctcaggga aaaaaataaa aatgttgaga gtagatggtg gaattactaa
    51901 aaataacttt acaatgcaat ttcaatccga catattaggc ataccaattg aaattgcaga
    51961 aaatcccgag acaacagtac ttggagtagg atatatggca ggtctttcct gtggtgtctg
    52021 gaacagtatt gatgaaatta gaagtgaatt tacaataagc aaaaaatata ttccaaatat
    52081 gactaatcaa aaaagagaag aaatattact tggatggaat caagcagtaa aaagagctat
    52141 gaattgggaa aacgatacca aaaaagtgtg tgctaattaa gttacaatag agtattttac
    52201 atgtatagga ggaattaaaa atgccctttg ataaaattat attatacata atggctgtgg
    52261 gagtgctttt aggagcgtta gatagaataa ttggaaataa atttggactt ggagagcagt
    52321 ttgaagaagg gtttaattca atgggtccat tggctttagg aatggttggt atagtttgtt
    52381 tagctccagt aatttcagat gtactaggtc ctataataat accaattttc aatctctgtg
    52441 gagctgaccc atctatgttt gcaactattt tagcgaatga tatgggaggg tatccattgg
    52501 ctatggaact tgcacacaat aaagaggcag gaatgcttgc aggattggtc gtgtcatcca
    52561 tgcttggatg tacattagta ttttcaattc cagtaggact aggtcttata gaatatgaag
    52621 acagaccatt ctttgcaaaa gggttactga taggcctgat aacaatacct tttggaggtg
    52681 ttataggagg attaatagca ggatttaact tatcaatggt aattataaat atgataccag
    52741 tgataatatt gtcagtaata ttggcagtag gtttaaaatt taattctaca cttatgataa
    52801 atgggtcatt agtttttgga aaatttatat ctatattgat aacgataggt ttgggagcag
    52861 cagcatttca agaaataaca ggtatagtac ttataaaagg catgacacct ataagagaag
    52921 ggattcaagt aattggaagt attgcaatag tgttattagg tacttttcca atattacatt
    52981 tattagttaa agttcttaat aaaccactta caatagtggg tggaaaatta ggtatggatg
    53041 ccactagtgc agcaggatta gtttttactt tagccaatag tattccagta tataaaatga
    53101 tgaaagatat gagtccaaag gggaaagtag taaatactgc ttggttggtt tgtgctacag
    53161 cagctttggg agaccattta ggatttacag caggagtagt tccagagatg attacacctg
    53221 ttgtaattgg aaaattggtt ggaggagtat tggcaattgc acttgccata cttatgacaa
    53281 aagatttaac tttagaagaa gaacaaagta ttaaaatgaa gaaagatgca gtgtagaata
    53341 aataataatt aagtcaaatt taaactattt taaagtagga gtttaaataa ctaaaaataa
    53401 attaaaaaga cagacaatta aaaaataatc gaatatccaa aacttataaa ttaaataaaa
    53461 tggcaatcaa ataactaaaa atgataagtt aactgaaagt aattacataa ttaaaatata
    53521 aagtatagtt tagacataaa tggagctaaa taaataatta tttggctcct taattttaat
    53581 ttattacatc aaggaactaa aaatcaatca tacaaactaa ttatcagcta tgactaaagg
    53641 tattcctttt tgagaaaact ctattattat attatggtct atactagcag aggtaataat
    53701 agtatctata tgttctatag gagctactga tgcaaatgaa tttataccaa acttaggagg
    53761 ttcgacaact actatagatt ttctagacct ttcaatcatt ttttttctaa caagtgcttc
    53821 ttctaagtga tagtcagaga ttccattttc aagagtgata cctccagcac ctaaaatagc
    53881 tttatcaaca ttaaattgtt caatagctga cagtgtaagc ggaccagaaa aagaaccttc
    53941 agtttctcta agatagccac caagcacata tacttttata ttagtattca taagttcgtt
    54001 tgcaactaaa attgagttgg ttattacagt tagattcttt ttatctttca aattttttga
    54061 aacttcaagt acagtagttc cagtatccat aaaaatagta tcatttgtat ttataaactc
    54121 actacattta atagcaatct gttttttatc gtttgagttt attttttttc ttttaacata
    54181 gttaagttct acgctacttg ctataactgg tatagcacca ccataaactc tttttaaaag
    54241 accgatactc tccatatggg ctaaatctct tcgtgcagtt tctattgata tatcaaacat
    54301 ttgaactatg tcatttattt taattatatt atctgatttg agaatactta aaatcttctc
    54361 gtatctttcc tgtggtaaca taaaatatcc tccttggact agtattattt tagttttggc
    54421 ataacttaca attaagtcag agtttaggta tatttgttaa tgtatgtata tttatcaaat
    54481 aatattataa gtgttatgca agataatttt accatattta aaacttacat ttaagcaaaa
    54541 aagtaaaaat agatgtttaa taattcaaaa taactcaaat tttataaaac aattgactaa
    54601 aatatgattt tattatataa tttattagta tagagatatg gagaagtact caagtggctc
    54661 aagaggatcc cctgctaagg gattaggctg ggtaaccggt gcgagggttc gaatccctcc
    54721 ttctccgcca attgttaaag gctattttta ttaaagatag tctttttatg atgtcataaa
    54781 tgattagata tgtataacta aagaaaggag ggaatagatg acaactttaa tttttttcat
    54841 agtggggata gcatctttgg tagttgcttt tgtaattgat ggggggcatg ttggagcgtt
    54901 atttgtattt tcatcagcac tcgttgtttt tggtggaact ataggagctg ttggagcttc
    54961 gacgccattc cctgtattta aaaagtctat aaagataatg ttattagctt ttaaaaataa
    55021 aaagcctaat aacatagaaa atataatcta tttcaaagaa attgcaacaa aggctaggaa
    55081 agaggggctt cttagtattg acaaggaaat aagtgataat aatgaattag acccttttat
    55141 taaaaaaggg cttgaactga tggtagatgg agtggatgca gttactataa gaagcatatt
    55201 ggaatcacag atacagataa catcaaaacg acataaagaa ggaattgcaa tttttgattc
    55261 agcaggtgga tatgcaccta caatggggat aataggtaca gttatggggt tagtacatat
    55321 tttaggtaat ctttcaagta atccagatgc attaggacct caaatttctg ttgcattttt
    55381 ggctactttg tatggtgttg gttctgccaa tttaatatgg ttaccaatag catcaaaact
    55441 taaggctata aatcaacagg aaataagtga aagacttttg gtgatagaag caatattatc
    55501 catacttgag ggtgataatt ctaatttaat gacagaaaaa ttaaaaatat ttttaaattc
    55561 aaaagaacta attgaacttg aagaaattgg tggtagagct gaataatata aaaggatgga
    55621 atgtttatgt tgtatgatga agatgaaaaa gaagaaaaca atgagcgatg gcttttaact
    55681 tattcagacc tcataacatt acttatgatt ttctttgtaa taatgtattc tatgagtaat
    55741 gttgatgcgg agaaatataa acaattatct caatctctaa attctgcttt tggtggttct
    55801 tctggagtta ttgaaggtgg taatagtaaa atagaaccag tagttgaacc aggaagtaat
    55861 gatttagata atttacaaaa tgctaagttt aaaaaagttg gtgaagaaat ccagaagtat
    55921 ttaaatgaaa atggtatggc taattcagta tcattaagag ttcaagatag aggattagta
    55981 ataagtctta aagatacaat actatttgat acggggaaag cagttgtaaa ggacaattcc
    56041 agagagaaga ttattcaaat aggtaagatg ttaaatgaaa tgaatagtta cattagagta
    56101 gaaggtcata cagacaatat gtctataaaa aattcagagt ttaagtcaaa ttgggattta
    56161 tcagttatga gagcaaccaa tgttgttcaa cttcttattg acaatgcagg tatagcacca
    56221 gataaattgt ctgctgtagg atatggtgag tttagaccga tagcagaaaa ttcatctgaa
    56281 gaaggtaggt caaaaaatag aagagtcgat atagttttag ttgatagtaa atatgataat
    56341 gtagaaaatg tttcaaatga taaatagtta aattagctgt ctcaacacag aattaattct
    56401 aaaggggatg gcttttttat gcgaaaatta aaaatagata gatagtaagt tacctttttg
    56461 tggtaatata tggtatctta aatatataat atttaaataa tatataagct caattaaaaa
    56521 aattttatag aggatgggaa atgaatggga aataaaaata cgaaatataa agataaaaca
    56581 agagaaaggt ataataaaaa agttgagaat ttaaataaag aaaaattaaa taaagctaat
    56641 aaagaatcta agaaagtaga taagattgat gatattatca ataaatctag cattgtatta
    56701 tgtgtacttc tagtagtgtt ttcattactt tacttattca aattagttca acttaatata
    56761 ataatgatac ttttagtaat tacagtagct attcaacagg gattggtgtc atttggtgca
    56821 tttagaaata aaaattatgt aaaagcttta ttttctatat ttgtaattgt atgtttctta
    56881 attgctttta aatatgttgt aaatcctgtt taaatatatc aataaacgtt ctataattaa
    56941 tataaatagt gaagttatag ttttaatgct attgtaaatt ttataatttg aaggagtaga
    57001 ttttatgaat aggtgtaagt ttgcaaaatt aattatcaca ttaatgatag ttttattact
    57061 tacaggatgt agtttaaaaa aggaagataa ttataagcta gacccagaaa atccgatatc
    57121 aatacaaatt tggcattatt ataatggaca gcaaaaaatg gcttttgata aacttgttaa
    57181 ggaatttaat gacacagtag gttctgaaag aggaattatt gttgaagcat tcagtcaagg
    57241 taatgtagtt gatttatcag agaaagtttt agattctgca aataaaaaag ttggctctga
    57301 agatgtacca aatatatttg cagcatactc agatactgca tatgaaatgg ataaattagg
    57361 gctactagta gatatggata agtacataag taaagaagaa ttaagtgaat atatagacga
    57421 atatgtagaa gaaggtagaa taaattctaa gggtgagttt aaacttttcc caattgcaaa
    57481 atcaactgaa attttgatgt tgaataaaac tgattgggat aaatttgcaa aagctacaaa
    57541 ttcaaatata aatgatataa aaacaattga aggattagta gagacatcaa aaaaatatta
    57601 tgaatggaca gatagtttaa cgaaagagcc taatgatggt aaagcgtttt ttggaagaga
    57661 tgctttagca aattatatta ttataggaag taaacaacta ggagtagaaa ttttttctgt
    57721 taaagatggt aaagttacat taaatattga tgaaaaagtt atgaaaaaac tatgggataa
    57781 tttctatgta ccatatataa atggatattt tgcttcttat ggtaagtttc gttctgatga
    57841 tgcaaaaaca ggtgatatat tagctcttgt aggctccagt tcaggagcag catactttcc
    57901 agatagagta atgctaaatg acaatgagag ttataatatt gaaacatctg tttttcaagc
    57961 gccacgtttt aatggagaag gaaaatatgc tgtacaacaa ggtgcaggaa tggctgtaac
    58021 aaaatctact aaagaagaag aatatgcatc agtagaattt ttaaaatggt ttacagataa
    58081 agaacctaat ataaaattct ctattgcttc tggatactta ccagtaaaga aaaaaacgaa
    58141 tgatttagag gttataaaag aagttatgaa gaaagataat ttgagcctat ctgataaagt
    58201 tgaaggctca atagcttcat ctattgaaca aattaacagt tgtaatttat atactaataa
    58261 agcatttgat ggtggaacta aagctagaca aatacttgaa tattcaatgc ttgataaagc
    58321 aaaagaagat ttaaataaaa taaatgaatt agtaaaaagt ggaacttcta agaaggatgc
    58381 agtagcacaa tttaataatg ataagaattt tgaaacttgg tttgaaagtt ttaaggctga
    58441 gcttgaaaaa gctataaaaa aatagatgaa ttggcagtta gtgtgtcgac aagcacaaag
    58501 gtataggtgg aataagtatg gaaaataatc taagaaaaaa caattcaata atgaaaaaga
    58561 tgatatttcc cctaattatt gttatgctaa ttcaaacaag tttattttgt gccacaattt
    58621 tatggggagg aactattaag aaattaaatg ataattcgtt tgacatctta aatgaaagag
    58681 taattaatcg taaaaattat atacaaaatg aaatgttaca aagatggtca aatacaagtg
    58741 aaacagaagc tagaattaat tcctctgtaa aaaaagtctt aaatgaaaaa aatgctttaa
    58801 ttgaggatgt aggcaacaat gaagaaatta acaaagacat tataagaatc atatcaaatg
    58861 atttaatata tcttttgaga aaaaattctg ttacaggagc ttttataata ttaagtgaca
    58921 aaaatattaa agataatcca gtagatagta atggtgaaat aagtaggact ggattatata
    58981 taagggattt agaccctaaa tttaatccaa atgataattc tgatttgtta attgagagag
    59041 gttcatcaga tatagcaaga agttttggaa tatctatgga cagttattgg gaacctaaat
    59101 tttcatttaa aagtgaaaat gaacaagaag gagatgattt tttttataaa ccatttagag
    59161 ctgcaattga taatccaaat gtatcaagtt ctaatttggg atactgggga agtaagtttt
    59221 tattgacaaa tgcaggtgat aggattatga catatacagt tccacttatt tatgaagatg
    59281 gaactgtata tggagtactt ggaatagatt taagtgtaaa ttatttaaga gaattacttc
    59341 catactcaga gataaatgga aataaaaaag gtaattatat tttaggtgtg gatagaaatg
    59401 atgatatggc atttgaaaat gtaatttcaa atggatactc attaaaagaa aagttttgga
    59461 atggtttaca ttctaattta gagcagaagg aatcgtataa aaatatatat aagattaaaa
    59521 ataaagataa tgaatgtggt aatggcaata tttatgctag tgtacaatac ttaaatttat
    59581 ataattccaa tactccattt gaaaatgaac gttgggctct tttgggtatt attgaagaaa
    59641 aaagtctttt atctttttca aaaagggtag agaaattagt tataatatct atagcaattt
    59701 ctttattaat aggtctaata ggtatttatg ttgcatctag attatttaca aaaccaattg
    59761 ttcttttagc caacaaagtt agaaacagta atccatcaaa accagtaaat cttgataaga
    59821 taaatatatc tgaaatagat gaattatctt cagctataga attactcagt gcaaatgttg
    59881 cagattcctc atcaaaacta tcgcagatta ttgaaatggt agatatgcca attggggctt
    59941 ttgaattata caaaaatgca gataatgttt tttgtacaaa agaatttttt agtgttttta
    60001 ttactgaaag caaatttgaa gaatatggtt atatggaaaa aagtaagttc cttaaaaaat
    60061 taaggggatt agataaatat ttgcaagaaa gttatgaaac agaaaataca tatatataca
    60121 agtttgaatc taaagataaa aagcctaagt gggtaagact gaatatcttt gaagatgagt
    60181 taaaggttct tggcgttgtt gttgatgtca caaaagagtt tattgagaaa agaaagatag
    60241 aatatgagag agattttgat attttaacga atcttttaaa taggagagct tttcattcac
    60301 agatacaaga aaaatttaag aataaagatg aacttaaggt agcagcattc attatgtggg
    60361 atttagataa tttaaagtat attaatgata catatggaca tgatgctggt gatgaatata
    60421 ttagatgtgc tgcagacata cttaagaagt ttatatcgtg gaatggtata gtatctagac
    60481 tttcaggtga tgagttttat gtatttatat atggatatga aagtaaagat agtataagag
    60541 atattattaa ttctgttaag aaacagatga ataatacctt attaaaactt catgatggaa
    60601 cagaatttaa aataagggca tcagcaggaa tttcctggta ccctgatgat tcaatcaact
    60661 atgatgagtt aatgagatac gcagattttg ctatgtatca aattaaaaat acaatcaaag
    60721 gtgaagttag tgaatttgat attaatatat ataataagga ttcattctta ttgagcaata
    60781 gagaagaatt aaacaagtta attgatggtc aactagttga atatgcattt cagcctattg
    60841 tagattgtaa aggtaaagta tttgcatatg aagcacttat gagacctaaa ataaaaactt
    60901 ttagttcacc aatagatgtc attagattag ctcgttcaca gtctaaatta tatcaaattg
    60961 agcgtattac atggtttaag gcacttaaat catttaaaaa atacaaagaa aaatttggtg
    61021 attgtaaact gttcttaaat tctattccaa ataataattt atcaaaagta gattttgagg
    61081 aaattgaaga tttatatggt gaatatttaa atagagtagt attagaaata acagagaatg
    61141 ataagattaa tgaagatttt attgagaaaa agaaagcata tatagaccat tggaatatag
    61201 aaattgcttt ggatgacttt gggacaggtt ataatggaga tgctgtacta ttatatataa
    61261 tgccagacta tgtaaagatt gatatgtcta ttgtaagagg tattgataaa gatgaaaata
    61321 gacagaaaat attaaaaaat cttatctcat attccaacga aagaaatatt aaagtgatag
    61381 cagaaggtgt agagacaaaa ggtgaaatgg aaacactaat taatcttgga atagattata
    61441 tgcagggtta ctatattagt aaaccatcat ttatacctga agatataagt gataaaatta
    61501 aaaaagagct caagatatgt catgaaaata ggaatgatgt ggtttaatag aggaaaaatt
    61561 aaatttattt ttatgaactt ttagtttata attaaaaaga aaataatata attataaatt
    61621 aaggtggtgg agctaataat cacaacaaat atagatataa gaaagttaaa tgaaaatcaa
    61681 ttagaagcag ttgagcatat agatgggcct tgcatgatac ttgcagggcc tggttcaggt
    61741 aagactagag taattacata tagaatagcc aatatggtcg taaacaaaaa catagcacca
    61801 acaagaattt tggcaataag ttttaccaag gcatcttcga tagaaatgaa aaatagagct
    61861 ttgaatttaa gtgatgatat aagacttaat aaggtaacct atggtacttt ccactctgta
    61921 ttttttaaaa ttctaagata ctttgaaaga tataatttag atagtatatt tgatgaaaaa
    61981 tcaaagcgaa tgacaataaa ggcaatctta aaaagtttaa atatagagaa tgctgatgat
    62041 gatgagaata taggacaagt tataaatgaa atttcctatg taaaaaatga acttatggat
    62101 aaaaatgaat ttaattcaga agtattaaca aaagatgagt ttttaaaagt atacaactta
    62161 tatgaagaac aaaaatctaa agttaataaa atagattttg atgatatgct tataagaact
    62221 tattatttac ttttgaaaaa taagtctgca ctagaaatgg ttagaaatgt gtataaatat
    62281 atattgatag atgaatttca agatataaat aaagtacagt ttgaagtttt aaagttaatt
    62341 tctagcccat tgaacaatat atttgcagtt ggagatgaag accaaagtat atatggattt
    62401 agaggtgcta gaccagattt tttgcttgaa tttgaacagt actttaataa tactaaaaaa
    62461 ataatattag atataaatta caggtctaaa agtgagatag tgcatactgc aaatagactt
    62521 atcgacaaaa ataagaatag atatgaaaaa gttattaagt gtagtcaagg tgatggagga
    62581 agtgttacct atatttctcc acatgattca gaggaagaag ccttatatat tgccaaggaa
    62641 ataattgacg aaataaaaaa agattatgta gagtattcag attttgcagt gatttataga
    62701 actaatatac agtcaagagc attagtagat gtatttatgg atatgaggat tccatttgta
    62761 gtaaaagatt cagtaattac aatatatgac cattgggcaa gtcaagatat actagcttat
    62821 ttaagaatag gtattaatcc aaaatcaaat aaagattggt tgagaattat aaataagcct
    62881 tttagatata tatccaaaga cagtataaat atggttaagg atgaaaaaga ttttataaca
    62941 gcattaataa ataagtgtaa tcttcatcct aaacaagtta aaacaataaa tgatttggaa
    63001 atagatttaa gctatttaaa tactttaaat cctaaaaatg caatatctta tattagaact
    63061 agccttgatt atgatagata cgttttagat tattgtagca acagaaagat aaagactaat
    63121 ggacttgtag agatattaaa tgaacttgag agctcagcaa ctaattttaa tactgttaca
    63181 gagtttttag agcatattga tagagtaaag actgagttaa cggaaaataa caagaataag
    63241 cagactgaag gtgttatatt tacaactatg catagtgcaa aaggattaga atttagaaat
    63301 gtttatatta taggtgtaaa tgaaggaaca atacctcatg aaaaatcata tgatatttgt
    63361 aaggaagaga aaaaagaaga acaattagaa gaagaaagaa gacttatgta tgttgctatt
    63421 acaagagctg aagaaaaatt atgtataagc tctactttaa ataagtatgg taagaaagtt
    63481 gataaatcat tatttattaa tgatataaaa tctccaacga aaaaagaaat tgatagtatt
    63541 ggtgtagggg ataaggtata ccataaaaaa tttcatgaag gagaaataat taaaaaagat
    63601 ggaattatgt ttacaataaa gtttaaagat agagagcgaa tcttggattt gaaaacttgt
    63661 ttattgaaga atataattta tactatttaa tttagaacct aaatttagat acaatgtatt
    63721 atttatatgg atagactagt aagaagtata ttctttattg tgtgtaagta aaagagatat
    63781 gtgtaaaatg tattatttaa gttattagaa aagagaaata aacgtttaat atattattta
    63841 tagttgttaa gaaaaagcaa aactgtgaaa gatattattt agcattattt aagaaaaagc
    63901 aaaactgtga aagatattat ttagcattat ttaagaaaaa gcaaaactgt gaaagatatt
    63961 atttagcatt atttagtaaa aagcaaaact gtagaagata ttatttagaa ttattatagt
    64021 aaaaagcaaa actgtagaat gtattattta agaaatagct aaaaatataa aatatactat
    64081 ttgtaattat ataaagaata tcaataaata tacacagtag tatttatata atttacaagc
    64141 aaaaattatt aaaaaaataa aaaacttatt gacaaaaata ttataaggaa gtacaattgt
    64201 attaacaatt taaggaaaca aatccagtga tagagaaagt agcatatatg gatttacagc
    64261 gagttaggga ttggtgtaag cctagcaatg aagtttatgt gaagagagct ctggaggaga
    64321 ttatcagaaa ttttagtatg ataattggtc tgcccgcctt aagggattga gaggataagt
    64381 acttacttat caaaaagagt ggtaacgcgg atataattcg tctcttagct gtaaagctaa
    64441 gggacttttt tgatttaaaa atcaaaatat ccatatagct aaagctaaca atcacaaatt
    64501 ttgaaagtaa tagaagtatt tatcaataag agtggtaacg cggtaaagtc gtctcttagt
    64561 cattaaagac tgagagactt tttttgtaac tcgaaacatt taagtattaa aatttgaggg
    64621 aaattataat taaaagagag gggtagttaa aatgaaagta tttaaaaaat tattaagttt
    64681 aggattagta ttaggattga cattatcgct agtaggatgt agcggtggag gagaaaagac
    64741 aaagttagaa caaataaaag acagtggaaa attggttgtt ggtactagtg cagaatttcc
    64801 tccatttgaa tttcacaagg tagtagatgg aaaagattca ataaaaggat tcgatataat
    64861 gttggctgaa gaatttgcaa aagaacttgg tgtaaaagtt gaaattaagg atatgtcatt
    64921 tgatggattg ataggtgctt taaatgcaga ccaagttgat attgttcttg caggtatgtc
    64981 tccaacacca gagagagaaa agagtgttga tttctcagaa ttatattatt taagtagaaa
    65041 tgcagttata gttaaagatg cagatataga caaagtaaaa actgaagacg atttaaagaa
    65101 acttagagtt ggagttcaag caggaagtat ccaagaagaa tatgtagtta acactttaaa
    65161 aatgacaact acaaaatctt taaaagcaat acctgattta attacagaat taaaaaatgg
    65221 aaacatagat gcagttgtta ctaatgaagc cgtttcttta ataaatgtta aaaaatatga
    65281 tggaataaaa atggcaaata ctgaagttgg aaaaaatgta acagaaggta tggctgcagc
    65341 aatcaaaaaa gctgacaata acaaagagtt tatagaacta ttaaacaaaa agataaaaga
    65401 attacaagat ggtaagaaga tagaagaatt tttaaatgaa gcatctactg aagctgcttc
    65461 aaattagtaa gaaagttatg tgggagatga aattatgagt ttagatttta gttttttaag
    65521 tagatttggg acttcttttt tggaaggaac aggtgtgaca gtatcaattt ctcttgtggc
    65581 attatgcttt ggatttataa taggtataat tatctgtatg gcaaaaatat caaagagcaa
    65641 agtattaaga gcaatatcat caatctatat tgaggtttta agagggactc cattattagt
    65701 acaaatatat atagtatggt ttggtttacc tcaattagga ataagattcc ctatgttgtt
    65761 tggtatacca agtgaattta tagctagtgc atttgcatta tcagtaaact ctggtgcata
    65821 tgtggcagag atacttagat caggcataca atcagttgat aatggacaaa tggaagcaag
    65881 tagatcatta ggattaaatt attggtcgac tatgagatat ataataatac ctcaagctat
    65941 aaagaatata ttaccttcat tagcaaatga gtttattaca cttgtaaaag aatcttcaat
    66001 aatatctgta ataggagttg ttgagataat gcgtactgct gatatagtaa aaaatgcagc
    66061 atttagagca ttagagccat taatagtagc agcagcaatt tactttgtta taacatttac
    66121 tctatcaaga ttagttggat tattagaaaa gaaactatct gtgtctaact agatgagagc
    66181 atgtttagca tttagggaaa acatagaata gtaaaaagga aagtgataat atgattacaa
    66241 taaaaaattt aagtaaatct tttggagatt taaatgtatt aaaaaacata gacttagaaa
    66301 tcgctaaagg cgaaataatg gttatagtag gcccaagtgg ttctggtaaa agtacacttc
    66361 ttagatgtat gaatttacta gaaataccta caggtggaga aataatattt gaaggaaaaa
    66421 atttggtcga taaaaaaact aatattgatg aggttagaca aaatataggt atggtgtttc
    66481 agaactttaa tttattccca cataagacta ttttagataa tataacatta gcaccaatta
    66541 aattaaaaaa gatgactaag gaagaagcag aaaaaaaagc agaagttttg ttgagtagag
    66601 ttggtctttt agataaaaaa gattcatatc catcacaatt atctggagga caaaagcaaa
    66661 gaatagcaat agctagagca cttgctatgg aaccagatat gatgttgttt gatgagccaa
    66721 catctgctct tgacccagaa atggtaaacg aagttttgga tgttataaaa gaacttgcta
    66781 aagaaggtat gacaatggca attgtaactc atgagatggg atttgctaag gaagttgcag
    66841 atagagttat ttttatagat ggaggaagta tacttgaaga taatactcca gaagaagttt
    66901 tcggaaatcc aaagcatgaa agaacaaaag catttttagc aaaagtgtta taatatataa
    66961 aaaggatgtt attgacatta gaaattcaat acatcctttt ttaatgatgg ttaatataaa
    67021 ttttaaaact aaagttatat taatattaac tttagttttt caaatctttg caaaaaaaaa
    67081 agagctcggg gtaagctctt tttttccacc gaattaattt ccgttactaa tccgattttt
    67141 aataaatata aaatatatcc ttatgaaagg gtattgggaa tagatatatt aactaactag
    67201 ggttaccagg gggataacct taatttatta taacaaaatg cgacacaaaa atcaatattt
    67261 tttttggaat aaattataaa agttattttt ataacaagta agcttataaa tttaactttt
    67321 atagtaaaaa taagtatatg tataatataa tatatttatt ttatataata tattatttta
    67381 tcatatattg tattttataa tgtatttttg tagggtatag tataagtata ttatatttta
    67441 ctataaaaat ttgtaataaa gtgaagaaac tagcttttca tgaaataata ttttataatt
    67501 taagattgtc tttttaataa agattaacaa aaaaaatact ataattaatg gtataatagt
    67561 tagagttgaa gattttaaat aaaggtaggt gtaattaagt tggaaatata cttagacaat
    67621 agcgcaacta caaaacctta tcaagaagtt atagataaaa tggtttatgc acttaatacg
    67681 gaatatggaa atccttcttc tgtccataga aaaggtgtag aagttgaaaa gggtataaag
    67741 gaagtaagac aagatgtagc taaatctcta ggagcgaaag aaaaggagat ttattttaca
    67801 tcaggtggta cagagtgcaa taatactata ataagaggta tcactagtct aaataaaaaa
    67861 agaaaaaatc acataatatc tactaacata gaacatcctt ctgtgttaaa tacattaaaa
    67921 gatttagaag aagatggttt tgaagtaact tatttagagg tcggaaaaga tggaaaaata
    67981 aatatagagg atttaaaaag tgcgataaag tcaactacat gcttagtaag tatgatgcat
    68041 gttaacaatg aaatagggac tatacagcca ataggagaag tcggaaagta tttgaaaggt
    68101 ttaaaagaaa agatttattt ccatgttgat gctattcagt catatggaaa aattaacttt
    68161 agaccatcta aatataatat agattttatg agtgtaagtg cacataaatt ccatggccca
    68221 aaaggaattg gatttatgta tataaaagaa aataatcgcc ttaagcctat gttaacaggt
    68281 ggtggtcagg aaattggaat taggtcggga acagaaaatg tacctgggat atatggtctt
    68341 ggagaagctg ttagaatact gaataaagat ttagatgctg tcatttcgaa agtaaataac
    68401 ttaaaaaata cattaaaaaa tgaaataatt gataatatag aagatataaa aattaattct
    68461 cctgaagatg gagtatgtca tatattaaat gtatcattta gagggacaaa aggagaagtt
    68521 ttacttcatt acttagagca aaaaggtatt tatgtatcaa ctggctctgc atgctcttct
    68581 aaaaagaagg gtagtcatgt attaaatgct ataggtctaa caaatgaaga aataaatgga
    68641 acaataagat ttagtttatc tgatatgaac acagaagagg aaatgttaga agctgtgaaa
    68701 gttttgaaag aatcaatttg tgacttaagg tcaataatga aaagaaaata aagaatactg
    68761 tataaatagt gagaataaat tagtttaaga ggtgaaatgg tgtataatat attaatagta
    68821 aagtatggag aaattggagt aaaaggaaag aatagatata tatttgagaa taggcttata
    68881 agaaatataa gaaatatgtt aaagccaatt ggcaaattta atgtatataa agagtatgga
    68941 agaatatatg ttgatttaga agattatgat tatgaagaag taattgaaga agttagaaaa
    69001 gtatttggga tagttggtgt atgtcctgga gtaagagcta aaaaagatta tgatacatta
    69061 aaagaaatag ctttaaaaat gttagaagaa aaaatagatg ctggatataa aacttttaag
    69121 gtagagtcaa gaagaggaga taagtctttt gggttgactt ctcaagaaat gagtatggat
    69181 ataggtggat acttattatc aaaggtagga gataagatta atgttgatgt aagaaatcca
    69241 gaagttaaaa taaaatgtga atacagagaa tttcatacta tggtctatag tgatactata
    69301 cctggatatg gtggattgcc acttggaacg aatggtagag ctatgtctct tttatcagga
    69361 ggtatagata gtccagtagc tacatggatg gttgcaaaaa gaggtatgga ggtagaggca
    69421 gttcattttc atagttatcc atttacaagt gaaaggtcac aggaaaaagt taaggattta
    69481 gctaaaatac tggcaaaata ctgtggtaga gtaagacttc ataaagttaa tatattagaa
    69541 atacaaaaag caattggtga gaattgcaat gaagaagaag ctactattct ttcaagaaga
    69601 tttatgatga gaatagcaca gagactttct gaaaaaagac attgtgatgc tttaattaca
    69661 ggtgaaagca ttgggcaggt tgcatctcaa actatacaag gtcttacttg tactaatgcc
    69721 gttgtagatt taccagtgtt tagaccactt atagccatgg ataaatcaga tatagttgat
    69781 atagcaaaaa aaataggaac ttttgaaaca tctatagtgc ctgaagaaga ttgttgtagt
    69841 gtattttctc ctagaaagcc tgttactaaa cctagattag agaaaataga aaaatctgaa
    69901 acagcacttg atattgaaaa actagtacag gatgcgattg acaaaataga ggtagaggat
    69961 attgagtttt agtacaaaag ttatttaatt attaaattga atattgagca tattggtagt
    70021 tctgttgaaa ggacttatat agacgattta ttaatatgta gtatttaaaa ataagtacta
    70081 taattttatt taatgggaat gattattatg aataaaaagg gttttacact aattgaattg
    70141 ttggtagtta tatctataat aggaatttta gttatagtag ctgttccagc gttatttaga
    70201 aatatagaaa aaagtaaggc ggttacatgc ctttctaata gagaaaatat aaagactcaa
    70261 attgttattg caatggctga ggaaccaagt aaagataaga ataaagtcat aaaagatgta
    70321 ctagaaaata aagatggtaa gtactttgaa acagaaccaa agtgtaaatc aggtggaata
    70381 tattcagcaa cgtttgatga tggttatgat ggaataactg gaggagaaag cattgcaaaa
    70441 gtgtatgtta cttgtacaga acatccagac ggtgttgaaa tggctaggga tgtacatcaa
    70501 agtatgaaag atttgattgc atcatttgca caagaccctt ctataatacc aggagcttca
    70561 aagagtaatg atgattttag aaaatattta ttagacaata aatataaaaa gggatggcct
    70621 acaattccag atgaatttaa agcaaaatat ggattaagta aggatacact atatatacaa
    70681 ccatatgcat ataatcctac taaacctgat gccactgtag ttgtatttgc aaataataag
    70741 actggaggta attggtacac ttccctagtt tacgattatg atgaaggtag atggtataaa
    70801 ggcaaaaatg gtatttctgt tgcaggtagg tcatgggatg ttgatacaga tagtgttaag
    70861 tctgtaaaaa cagagattca ttctaaagag ggatggggtc ctttaaatta atatataatg
    70921 ttttattaat ctggtattga ttaaactata gaaaagagca gtttctatag atgacgaata
    70981 ccagattttt atttatatgt ataattaata tatattaaaa gtatttatat ttttaagtct
    71041 tcacatgtaa gctaaaaata attataataa tgttgtaaag aagtttaact acaagattaa
    71101 ttttctgaag atttagtatt tatactaaga aatacacaaa aaggggaata gatatgatta
    71161 ataattttca agacaaccaa acaataaatt taatacaaag tcgtagaagt atacgaaaat
    71221 ttacaacaga acaaattagt gatgagcaag taaacacatt attacactgt gcatttgcag
    71281 caccttcagg atgtaataaa cagccttggc acataactgt tgtgcaagac cagaaacttt
    71341 taaaagcgat tagtgatgat actttatcta ggattcatga ggtgagtaat gttgagataa
    71401 ataaaaactt taagttattt tatggtgctc caactgtttt atttatttct tatgatgaaa
    71461 gtagctcatg ggctccatat gatgtaggaa tacttacagg gaatataaca acagcagcac
    71521 aagcactagg gcttggaagt tgtataatag gtatgattag aggattattt acacctgttg
    71581 aacaaggaga tattgaaggt cttgtgagtg tattggataa agaagatgta aaagaatcag
    71641 agtcaataaa gatgaagttt gatacaaata aaaaatacag agagatactt gatataccag
    71701 aagggtattc tgtaccattt ggtattgcta taggtattcc agatgggaat ttaccaaatg
    71761 ctagagaggt agtttataaa gtttctagag tttaggataa agtattgcaa caatcaatcg
    71821 gttatttgaa gaattaaatc ggtaatatcc aaataaacta atagaagaga aagctattta
    71881 aaaagtagct tagatttttt attgtaaaat aattaaataa agaatagggt gataagtatt
    71941 ttatttatta tcctattctt ttttatttgt agaatgataa aaaaatgata aaaacaagaa
    72001 ttaagtgtaa tacaatgtaa ataaagtgtg ttaattttga gtatatgttg taaagtttat
    72061 caaaactgaa aaactcaaga tatattttca gtataatagt gtataaaaat agggtaaagt
    72121 ggaagtctcg aagtctctta aaaatttgca cttttcccta ttttattatg ttttctataa
    72181 aggttaatat acactaacta ttatatactt tcactccaaa tttagagatt atttcactag
    72241 ctttttgaac atcttcctta gtggcatcag gaacatcttt tagttcataa tcgataccta
    72301 aattttccca tttgtgtatt cccatagaat ggtatggtag caattcaaat ctttctacat
    72361 ttttcaatgt agctacaaat ttacctagtt tttctaaatt atctacatca tcagtaatac
    72421 caggaactaa aacatgtctt atccatacag gaatatttct tgattctaag tgtctagcaa
    72481 gttttaatgc cttatccata ccaacaccag tcaaatcaat agatttttcc tcaaccatat
    72541 gttttaaatc aagtaaaacc aaatcagtat tgtctaaaac tgggtctata gtttctatat
    72601 ctacgaatcc agatgtatcc aagcaagtgt gtatatcatt ttcttttgct tttttaaata
    72661 attcacttaa aaactctggt tgaagagtgg attcaccacc agaggcagtt atacctccat
    72721 cagaaaattt cataaaagaa gtatacttaa gagcatccgt tattatttca tcaactgtat
    72781 attcttttcc tgatttaata tcccatgtat ccctgttatg acagtatttg catctaagag
    72841 gacacccctg aaaaaataat atatatctta ttcctggtcc atctacagta ccaaacgttt
    72901 ctatagaatg tatttttccc ttaatcatag agttcacctc acaatatatt ttaataacct
    72961 tatcaatagt tataatattt ctctaaaaaa ggccatctta taccagaaat aattcaaata
    73021 taagatagcc ttttattttt attttctaca cagtagtaat cttagttaaa gtataaaaat
    73081 ttaaagacta agccatttta ccgtggaatg ttctgtttat aacatctaat tgttgctctt
    73141 tagttaattt tatgaagtta acagcatatc cagatactct tatagttaat tgtggatatt
    73201 cttctggatg ttccatagca tcttctaaag tagctctatc aaatacattt acatttaggt
    73261 gatgagcatt ttgagcgaag tatccatcca tcattgcaga aagattgttt attctttcag
    73321 tcatatcttt tcctaaagca gcaggtacta tagagaaagt attagatata ccatcttgag
    73381 cgtgctcata tggtaattta gcaactgaag ataatgaagc taaagcacca ttagtatctc
    73441 taccatgcat tgggttagca ccaggagcaa atggagcacc agctcttcta ccatctggtg
    73501 tattaccagt tttcttacca taaacaacat ttgaagttat tgtaagtata gattgagttg
    73561 gataagaatt tctataagtt ttattttttc ttattttatt cataaagctt tcaactaact
    73621 ctacagctat actatcaact ctatcatcat tgtttccgta ttttggataa tctccttcta
    73681 tttcaaaatc aacagctatt ccttgttcat ttctaatagt tttaacctta gcatgtttta
    73741 tagcagataa tgagtctgca caaactgata atccagccat accacaagcc atagttctaa
    73801 atatatctct atcatgtaat gccatttcta atgcttcata agaatattta tcatgcatat
    73861 aatgtattac atttaaagta tttacatata atgttgctaa ccaatcagtg aatggttcaa
    73921 atttactcat aacttcatca taatctaagt actcagaagt tataggttca aatcttggtc
    73981 caacttgaac gccagatttc tcatctacac caccatttat agcatataat aaagttttag
    74041 ccaagttaac tctagctcca aagaactgca tttgtttacc aattctcatt gcagatacac
    74101 aacaagctat accataatca tctccccagt atgctctcat taaatcatca ttttcatact
    74161 gtactgaact tgtatctata gatactttag aacagaaatc tttgaatcct tgaggtaatt
    74221 tagttgacca tagaactgtt aagtttggtt ctggagaagg tcctaatgta tatagagtat
    74281 ttaacattct aaatgagttt ttagtaacta atgttctacc atctattccc atacctccta
    74341 tacactcagt tacccaagtt gggtctccag agaataggtt attgtaatca ggagttctta
    74401 ggaacttaac cattcttaat ttcataacaa aatggtccat atactcttgt aattcttctt
    74461 ctgttacgat tccagctttt aaatctcttt caaagtatat atctaagaaa gtagatgttc
    74521 tacctaaaga cattgcagca ccattttggt ctttaacagc acctaaataa ccaaagtata
    74581 accattgtac agcttctttt gagttagttg ctggttttga tatatcaaat ccataagatt
    74641 cagccatttt tttaagttca tttaaagctg atatttgctc agttatttct tctcttaatc
    74701 tgataacttc ctcatccata caagaaactt ctaatgattt cttttgctca tttttatctt
    74761 ctattaaagc atcaacaccg tatagagcaa ctcttctgta gtcaccaatt attctacctc
    74821 taccataagc atctggaaga cctgttatta taccagattt tctagcagct ctcatttctg
    74881 gagtataaac atcaaaaact ccttggttgt gtgtttttct gtatttagta aatatatctt
    74941 ttatttctgg gtctaattca tatccaaaag cttcgcatga attttcaacc atcttgatac
    75001 caccatatgg catgacagct ctttttaaag gggcatccgt ttgtaaccca acgattgttt
    75061 ctaattcttt atctaaatat cctggagcat atgcagctat tccagaaaca gtttttgtat
    75121 caacatctaa agtaccacca ttttctcttt cttttttaaa tagaaccatt gctttgtccc
    75181 ataatttttt agtattttca gtagcaccag ctaagaaaga gtcatttccc tcatatggag
    75241 aatagttcaa ttgtataaac tctctaacat ttatttcttt agtccatctt cctgttttaa
    75301 atccttgcca tgcattcatt aagtatttcc tccttagatt taaatgataa ataatactat
    75361 taaaattaat ttttatatac ttaatttatt ttatatattt tttaaaaaat atattttcta
    75421 atataataat aacatattat tcgtatcctg tatacataaa aaataaaaaa ttgtcgcttt
    75481 aaagtataaa acagattata tgttaataat atggtgaaat tatacccata tacaaataaa
    75541 ataaaacaaa taaatagcta attaaggaga aaatattttt tattttttgt ttagaataaa
    75601 taaattttat tatggaaaaa agaaaaagca tacatcttca caaactgaat atttatttaa
    75661 tagggggagg tgatatattg tttatcacag tggtattatt tttagtaggt ttcctattaa
    75721 ttactaaggg cgcagatatc tttataaatt gtacggtaga gataggtaga aaaacgaata
    75781 tatcagaaat tatacttgga gctactatag ttagttttgc aacaacatta cctgaattta
    75841 cagtgtctct acttgcttct attgatggtc atactactat gagtttagga aatgcagttg
    75901 gttctataat atgtaataca gggttagcat tagggttggt tgtttttcta agtccattta
    75961 atgtagataa aaaaatgttt ttttctaagt ctttactatt aatagtatcc gttatagttt
    76021 taattttatt gagtttagat ggagttataa caagaggtga ttcgttatta cttataataa
    76081 tattaatctt ttatatggtt aataattata gaagtgtcgt tggaaaatct gatactaaaa
    76141 gtagaaatat taaaaataac actattaaag acatatctac taaaaaaggg aaaaattata
    76201 gaggtttttc cgtattagaa attgtaaaaa tactattact ttttgctacg ggattgataa
    76261 tgatgataat aggttctcaa atccttatag agagtggggt aagaattgct agctttttaa
    76321 atatacctca aggtatagta agtttgacta taatagcact tggaacttct cttccagaaa
    76381 tagtttcatc aattacagct ataagaaaaa atcatcatga aatatcagta ggaaatattt
    76441 tgggggcaaa tatattgaat atagtgtcag taatagctat atcagcaata ccaaataata
    76501 taccgatact atctcaaaat agacaattag atataccatt catgatatta ttgatattaa
    76561 tagtaataat accaacactt aaatcaaata gacttagtag aatacaaggt atattgatgt
    76621 tattcacata ttttctgtac atatcaattt tgtatttcat gtatattatt taactatact
    76681 gttaaaaata ttaattgcag aatattctaa aaaagtatat aatggatagg ttaagattaa
    76741 ttgataacgg agaggaataa tatatgaata taacaaagtt tgaagattta ccaataagtg
    76801 agggaataaa aaaagcaata gctgaaatgg ggtttgaaga accatctcct atacaagcac
    76861 agtctatacc tgcgattttg tcaggtaaag acgttatagg acaggctcaa actggtacgg
    76921 gaaaaacagc tgcttttagt atacctatac tagaaacaat agacccaaat aatagaagtt
    76981 tacaagctgt agtactttgt ccaacaagag agcttgcaat acaagtatca acagaaataa
    77041 gaaaactagc taaatattcg cacggaataa agacactacc tatatatggt ggtcagccaa
    77101 tagatagaca aataaagtct ctaaagagtg gtgtgcaagt tgtaataggt actccaggac
    77161 gtacaataga ccatattaat cgtaaaacat taaaaatgga taacgtaaaa atgattatat
    77221 tagatgaagc agacgaaatg ctagatatgg gatttagaga agatatagaa atgattttaa
    77281 gtaagattcc agaagaaaga caaacaactt tcttttcagc tactatgcca agaggaattt
    77341 tggaattaac taagagatat caaaaagacc cagagcatat aaaagttgtt agaaaagaac
    77401 ttacagtttc aaatacaaag caatactata tagaaactag gtcatcaaat aaattagaag
    77461 tattatgtag attagttgat gtatatgacc ctaaattatc tgttgttttc tgtaacacta
    77521 agagaaaagc agatgaatta gtaggagact tacaagcaag aggatatttt gcagatgcat
    77581 tacatggtga tttaaagcag actcaaagag atatagtaat ggataagttt agaaatggta
    77641 caatagatat acttgttgct actgatgttg cagctagagg tatagatgtt gatgatgttg
    77701 aatgtgtatt caattatgat ttaccacaag atgaagagta ttatgttcat agaatcggta
    77761 gaactggtcg tgctggtaga gaaggtatgt catttacttt tgtatttgga aaagaaatga
    77821 gaaagatgaa agacatagaa agatacacta aatctaaact gataaagcat aatataccaa
    77881 cgataactga tgttgaagag aaaaaagtag gtactttctt tgcacaagtt aaacagacta
    77941 tcgaagaagg gcatttaact aaacagctac agtggttaga aaatttctgt aatgatgaag
    78001 attatgcaat ggttgatata gctgctgcac ttgtaaaact atctctaggt gaagaaatga
    78061 aagaagagat aatagaagaa aaacctagaa gagagcgtgg agatagaaaa ggtggtactg
    78121 gagctaaaga tggtatgatt agattattta tcaatattgg tagaaatcaa agagtacaag
    78181 caaaagatat agttggtgct atagctggag aagttggaat cccaggtaaa gtagtaggca
    78241 ctatagatat atatgataag tatacttttg ttgaaatacc taaaaaagat gcaaaaacag
    78301 tgattgaaaa gatgaaagat attaagataa aaggtaataa gattaatata gaaaaagcaa
    78361 ataaaaagaa aaaataacgt atagtataca aaactataat tagaaaatat ataaaataat
    78421 atattgaata tttaaaaagc ctgatgtgtt ttcaaaacag atagtagata atctgtaata
    78481 gttaacagca taaggctttt attgttttat ataatattat tgttaggagt gtattaaaat
    78541 tagtttataa atagattcaa tatacaagaa ataatatatt aaaaatatgt aattaaataa
    78601 aatttaatat atggtttttg tttaaaagta gaatttaata ctttaattta taattttcca
    78661 tgctattgtg aaaaagtgta tattagttct tctttttcaa atagtatttg aaaaagagaa
    78721 tattaattat ctatatagtt tagattataa taaaaaatgt aagataacaa aggggagaaa
    78781 aagatgtcaa tgacttatat ggaccctagg gtttttttga ttttagaaat ggtgttggaa
    78841 gaagatacaa atactttaga acaattttca agtgttctag gtgtcagtac taggactatc
    78901 agaaactata taaaccagat taatcgagaa ttaaaagatg gtattgccaa aatagttaaa
    78961 aatgaaaaag gtacatatag tataagagtt gaagatgaaa gtaaattaat tgagatagta
    79021 aattttaata gagtaaagct gtcaaatttt ataaatttaa attcacctga tgaaagaata
    79081 aattatgttc ttgatatttt aactatgact aacaatccaa ttactataga tgatttggct
    79141 gaagagatat gtataggaag aacaacatta ataaaggatt taaaaaaagc agacagaatt
    79201 ttagctgaat acgatttaga attaaaaagg aaaccaaata taggtatgat tttagttggt
    79261 gaggaaatgg atataaggtt gctagtcctt gacagattgt atgaaaatta tattgatgtt
    79321 ttggaaaacg ttaatcaaat aaatttagtt aaagattatg atattgaatg tcttagagat
    79381 gaattaaaaa agttatttaa aaaagaagaa ctatacataa cagaacaggt attgagagat
    79441 gttgaaagat atataataat atctgcttta agaaatctaa atggttataa atttgaaaag
    79501 atagataaga gatttgaagt aataagatgt tcagatgaat acactttagg attaaaactc
    79561 aaagctttat tggaaaagat attcaatata gttttaaatg aaaaagaaac catatttttg
    79621 acaatgccat taataggtag aaaagctcct agtacaaagt tagcacttag cagtataaag
    79681 ataaatgata gtgtaaagga agttgtagat gaagtaacta gttttttatt agagacctca
    79741 ggaattgatt ttaaagaaga taaaaagctt atagaaaatt tagaatatca cttgtatttc
    79801 gcacttaata gaatgagatt caacatacga gtaaaaaatc cacttttaca agaaataaag
    79861 gaaagatata catttccata tagtgttgca aagatagctg caatgataat tgaggaaaag
    79921 tttgacttga aaatatgtga ccacgaaata ggatatatag cattgcattt tggaagttat
    79981 tttgaaaaaa attcaagaaa agttctaaat gtaaataggg tagctgttgt ttgtggaaca
    80041 ggtcttggga ctgcacaact cattagaata aagataggaa aaatacttgg agagagtgta
    80101 gaagtaaata ctttttctga tatagaagct aaagctaatt tagatttatt aaagtactat
    80161 gatttagtat ttacaacagt agatttcaag acagacttag atgttccaat ttttagagta
    80221 aatgcgttat ttaatgaaga aagtataaag aaagagatag aagatgcaat acttttgaaa
    80281 aatagtataa atattaagtc tataaaaaag attgaaaaga atattccttt tataggtaaa
    80341 ttaattgaag aggataagtt ctttatattg aataagggta cattcatgga aaatttagaa
    80401 gagatgttag agaagctagt tcttaaagga attattgata tagagtttaa agaaaatgta
    80461 ctaaaaagag aaaagaaatc ttcaacagca ttagataatt atattgcatt gcctcactca
    80521 gttagtccta atgaagagaa cctttatttg gcatttggaa tattagaaaa tccagtaatt
    80581 tgggatacaa aggaaattag aataataata ttgatgataa ttccggacaa gaatgtgggt
    80641 agtacagaac tgataataaa aagctatgaa gaagtacttg aaataggaag agataaaaaa
    80701 atagtagaaa aactttctaa agtaaaatca tttgatgaat tttacaaaat aattaccacg
    80761 aggaggtaat aatatggacc cagtaatttt tattatagta tcatttattg tagtttattt
    80821 attgaatatt ttccttggat atttacagat taaagatttt aataagaatt atattgaact
    80881 aaaaagaaaa ggaagagtgg caataggcag aaagaaagga agaatttcat caggtgcaat
    80941 tgtgttgata cttataaatg atgatggtgt gattatagag actagaaaaa tgcagggtgt
    81001 tacagtagta gcaagagtaa agtcatttga aggtttggta ggaaaaaact taaagtacat
    81061 agaaaaatca gatttaactg tttacaataa actacttaaa aaagcaatac tagatgcagt
    81121 caaacagtac ataacatttg agaagaataa atgtgaagat atgagtaatc ttagtactga
    81181 tgaagaatgt aggatggaag tagtttaaaa aaatatatct ataaggagga gttaatatga
    81241 cacaattttt tcaagtatta gcgagtggtg cagatagttt tatgaattta tttagggcag
    81301 gtggacaaca atttgtaggt tttgtaacag atatagtacc acttttagta gcattattag
    81361 ttacaatgaa tgcaattatc aactttattg gtacagatag agtcgagagg cttgcaaaaa
    81421 aatgttctgc aaatatattt actagatatt tgatactacc agttcttggt acatttgtat
    81481 ttgcaaatcc aatgacacta tcattgggaa gattcttacc agaaaagttt aaacctagtt
    81541 actttgcagc agcaagtttt tcatgccata caatgaatgg attatttcca catattaatc
    81601 caggtgaact atttatctat ctaggaattg caaatggtat aacaactttg ggattctcaa
    81661 cagcagattt agcagttaga tatttgttag tgggtatagt tgcaaatttt attaaaggtg
    81721 tagttactga ctatacaaca aaatttgtag agaagcaaca aggaatagca ttaaattcag
    81781 atataaagat tgggtaatta ctttaaggta taagtaaact acttaaataa aaagatagtg
    81841 tatagaggag gagaaattat atgtcattta acaaagttaa aataataaag ggttctggag
    81901 gatggggtgg accattgata atagaaccaa cagaaaagaa gaataaggta gtatatgtga
    81961 ctgggggagc aaagccagaa actgcagtaa aaatagctga acttacagga tgtgagttaa
    82021 tagatggatt ttcacaaggt gttaaagatg atgaaatcgc atgtgtaata ataaattgtg
    82081 gtggaacatt gagatgtggt atatatcctc aaaagaaaat accgactata aatataatga
    82141 aaacaggaaa aagtggacca ttagcaatgt ttataaaaga agacatatat gtttcaggag
    82201 taaaaccaac aaatgtagag cagttataat ttagatagta ggaggaaaga aatatggctt
    82261 atgatactaa aaagaagata agtgaacaga gtcaaggaat tgttgcaaaa ataggtatag
    82321 cactaggtaa cgtgacaagc actctttttc aagctggtag ggatactata gatacattaa
    82381 tacatactat actgcctttt atggctttcg ttgcagtcct tataggcata ataaatcaat
    82441 caggtatagg aaattgggta gccaatttac ttactccatt aatcggaaat gttggaggtt
    82501 tagttgtttt atcaataata tgttcatttc cgttgttgtc tccatttctt ggaccaggag
    82561 ctgttatagc acagatagtg ggtgtattgg ttggtacaga aataggaaaa ggaaatattc
    82621 cgccaagttt agcattacca gcattgtttg caataaactc acaagcagcc tgtgacttta
    82681 taccagtagg tcttggtctt gcagaagctg aacctgatac agttcaagta ggagttccat
    82741 cagttttata ttctagattt ttaacaggtg cgccaaccgt tctattagca tggttagcaa
    82801 gctttgggtt atataaataa aaggatactt tataaataat tagagagagg ttcaattgat
    82861 atggaattaa tatacagtac tcaaataaat aaaataggag ataatgcaaa tgaattttta
    82921 caacataata tgtttgtaac tttcaaagat aatgctcctc aagaattaga aaattactgt
    82981 tatatacatt ctgaaaataa tttagtaaaa gaaatactta cgaatgatgt attatcaata
    83041 aataatgttg attataaaat tacttctgtt ggtgagttag taaaccaaaa tctttcagaa
    83101 ttaggtcata taacatttaa gtttacaggt gaaaaagatg gagcaattgg agggacctta
    83161 tatcttgaag aaaaagaaat agcacctatt ggcgtaggta ctatactaaa aataattaga
    83221 aaataaaatt taaaacgaat ctaatcatat tataagtaaa ttatagataa aagtcaattt
    83281 aactaatcaa gttaactttt aatatgatac aaaggggata tgaaaatgag aaaagtagct
    83341 ttagtcgttg gaggaggaag aagtttaggt gaatatttat ctaaacattt agctaaagta
    83401 ggttatgatg ttgctattgc agatttaaat gaagataatg caaaaaaagt agctaaagaa
    83461 atagaaatgg aatttggttg taaatctgta ggatatggat gtaatgctat agatgagata
    83521 caggttatga gtactatcaa agctattgaa aatgattttg atagaataga tttattagtg
    83581 tacaatgcag gagtggctgt aagtaaaaaa ataacagatt ttggatacaa agattttaaa
    83641 tttattgtgg atgtaaattt aaatgggtat tttctatttg caagagaagt gtctaaagtt
    83701 atgatagcaa aaggtattga gggtagaata atacagataa attcaaaatc aggtagagta
    83761 ggaagcaaac ataattcagg ttattcagca ggtaaatttg ctggagtagg acttactcaa
    83821 agtttagcac tagatttggc agaacataag ataactgtaa atgcactgat gcttggtaat
    83881 ttgcttgatt ctgacatgtt tgaaagttta attcctcaat atgcagtaaa attgggaata
    83941 cctgaatcag aagttaagca agtttatata gataaagtac ctttaaaaag agggtgtaga
    84001 tttatggatg ttgcaaatat acttacattt tatgcttcaa aggaagctga atactgtact
    84061 ggtcaatcta taaatattac tggtggacaa gttatgtaaa atttttatgg gagtgtctca
    84121 agatgaactt tttagtttat gagacacttt ttttgtataa aattaaatat atttttagca
    84181 tttgaataaa aaagaggctt atctatattt tgaatcaacc tcatttttgt aattaagaaa
    84241 tatggtattt aagtaagcat ataagatttt tagtttttta gaagagaaat tttcactaat
    84301 attatattta tgaagtattt ttaaacttaa tttgataaaa tatatctatg ttttgtatac
    84361 tgtagttttg aacatataag gtttaataaa ttatagtata tatgttaaat tttaataatg
    84421 taagaaaata gaaagaagga tattttatgg atataacaaa aaaattaagt catggatgta
    84481 cactagattg ccatgattgt tgtaaattca atgtctatac taaaggaaat aatgtagtaa
    84541 aaattgaagg agataaaaat catccttaca caaaaggttt tatatgcaaa aaagggatgg
    84601 ctcatttaga tagattaaat cataaagata gaataaagac tcctatgctt aaagttgatg
    84661 aagtatggaa agagatttct tttgataagg ctatagaaat aatggcagaa aaacttacat
    84721 actataaaga aaagtataca tcaaagtctg tcatgcatta tgaccaatat ggaagtgggt
    84781 ctgtactaaa atacatagga gatatatttt ttaattttta tggaggtgtc agtaggcata
    84841 agggaagtcc atgttggagt gcagggatgc atgctcaaaa atatgatttt ggagtagcta
    84901 agagccatgc gatagaagac atgttaaaca gtaaaagtat atttgtgtgg ggaaaaaatc
    84961 cagcatacac tacaattcat actatgcaaa taattaaaaa agctaaagaa aaaggtataa
    85021 agatagtagt gattgacccg atatatacga aaacagctca aatagcagat aagtatatac
    85081 aggtaaatcc tggaacagat ggagctttag ctatagctat ggcaaaaatt atagtagaag
    85141 ataaattata tgatgaagaa tatataaact catacgttat tggttttgaa gagtataaaa
    85201 gatatttata ttcgttggaa ttaagttttt tgattgatga atgtggtgtt aaagagaatg
    85261 atataagaga gttagttgct ttatatacta acaaatattc gagtataaat gttggatatg
    85321 ggcttcaaaa atataaaaat ggtggaaaca caataagagc tatagatgct ttaggagcta
    85381 taactggtca aataggattt agtggtggag gggtaaacta tgctaataaa gtttacccaa
    85441 gtgttataaa ttctgaccct tacaatagta aattatatgg tcaagatagg gagttttatg
    85501 taagtaatat cagtaaattc atagaagaat ctttaagaaa tacatcaaat aaaataaata
    85561 atgtatcaga tgaacctgat acaaaatcaa ataaaacaga ttatatatca aatgacttat
    85621 atagcttatc tggtaagtca attaaagata atattcctat aaagatggct gtgataacta
    85681 aaagcaatat gctcaatcaa ctgccagatt tagtagaatt ggagagggtg ttttcaaaaa
    85741 ttgaatttaa agtatgtttt gatatgttta tgactgatac agccactcta tgtgacctgt
    85801 ttataccttg tacaaataca ctagagagtg aagatataat ttatagttca atgactaatc
    85861 catatataac ctataatgaa agagctgtaa agccagcaca taaattgatg gatgaatatt
    85921 acttctttat ggagctagcc aaaaagatga gattaaatga ttatccattt gtagaaaaga
    85981 gcacttattt agaaaaagtg attgaaccac ttaagtgtgt tgacaaaaat ctggatatag
    86041 aaaaacttaa aaacaattac tttactatac ataaccctgt tgcttgggaa gataagaagt
    86101 ttgagactcc ttctggaaaa tacgaacttt attcagaaag tataaaaaac ttgggaataa
    86161 atccaacacc tgtatatata aacaataaat ataaagagat agaagataaa aatgaaaata
    86221 tttcttttag attattaact aaccatcatg cggatacttt atttagtcag cattttatgg
    86281 ataaaaaatc tatagctcaa gcatatataa atcaaagaat ggctaaaaaa gtaggtatca
    86341 aggataaaga tactgtgata ttgaggtcaa aaaaagcaaa aataaatgta caaataaata
    86401 tagatgatgg agtaggtaat tatatagtaa aaatgtatgt tggatggtgg aagaaacatg
    86461 gaaatcctaa tattttgaca gacactggta tatcagattt tggtggtcag gtaacatata
    86521 atgaaagtat agtagaaata atacgacaaa actagttaaa tttcattgaa ggaataaaaa
    86581 tataattata gaattgatta aaagttacta tttttacaaa actattgaag gagggatttt
    86641 gatggtaaat tattccttag aacataagaa tctatacata gaatttatgt gctcagaact
    86701 agaccaccat gtagccaatg aaataaggga agaaatagat aacttattaa gtgtaaatca
    86761 agtaaaaaat gttgtattta attttgaaaa tattaatttt atggattctt caggtatagg
    86821 tgtcatcata ggtagatata aaaagatttc taatgaaggg ggacgagttt cagtaattaa
    86881 tataagttca cgagttaaga agatttttga tttatctggg ttaaataaaa ttattggcat
    86941 ttatgatacg tatgaagaag ctctaagttc tttgtaggga ggagtatgtg atgaataata
    87001 ttatggaagt taaattttcg gcaatatctg aaaatgaaag tttagcaaga gttatagtag
    87061 catcctttgc agctaagtta gacccaacag tagatgagtt agtggatata aaaactgctg
    87121 tctctgaggc tgttacaaat gctataatac atggatatga agaagacagt tctaagtttg
    87181 ttttcttaag atgtgagata gagggaaata ctataaagat tatagttgaa gatgaagggt
    87241 atggaataga aaatgtggag aaggcaatgg aaccacttta tacatcaaaa ccagaacttg
    87301 atagatcagg aatgggattc acagtaatga aaagctttat ggacgatgta gaggtaagtt
    87361 ctgtaaaaga taatgggact agaattgaaa tgactaaaaa aataaatgtg cctaaataaa
    87421 gtccaaaagt gaggttttat tatggaagta actgttgcca gagaagaaaa aaaacctctt
    87481 cttagtcatg aagagactct agaacttatt gaaaaagttc aaaatggaga tgaagaggca
    87541 aaagaaatat taatatcaag caatttaggt ctagttagga gcgttgtatc tagattttta
    87601 aatataggat atgatagaga agatttattt cagttaggtt ctataggctt aataaaatca
    87661 atatataaat ttgacccaaa atttaatgta aaattctcta cttatgcagt accaatgatt
    87721 ttaggtgaga taaagagata cttaagagat gatggtatga taaaagtgtc aaggtcgtta
    87781 aagcaaatag ctgtaaaggc aaagatggaa agtgaagctt taactaaaaa attgggtaga
    87841 gaaccgagca tagaagaatt agctaaagca atagatgtag aaaaagaaga tttagttatg
    87901 gctatggaag ctaatttcaa tgttgagtat ttacaaggag ttattcatga agaggaaggc
    87961 tctccaatat gtcttattga taaaataagc atgaagggag aaagtgaaga agagaaagta
    88021 gtggacaaca tattgttaaa agacatactt ggaagattgg ataagagaga acgtcaaata
    88081 atagttctca gatattttga agatatgact caaagtgaaa taggagagat gcttaatata
    88141 tcacaagttc aagtatctag gatagagaag aaagtattgt ctaagttaaa agaatacata
    88201 tcatgacaat ccttatgata tgtagaataa caaaatataa taatataata aatgtattac
    88261 taaaataaaa tgtaataatt ttttatgtta agtttttaaa ttattaaaat atattaaaat
    88321 aataaagagt ataaaaaaat aaaaatatta aaacaaggtg tctttatggg aaaatagatt
    88381 ttttctttat taggcatctt ttttattttt tgactaaact ttagatagtc aaaataaata
    88441 ataggtttat ttttttaaaa ttaacaaata atactttaga gaggtgttta gtatggataa
    88501 aaattataaa aaatatgtag accaaataag cccaaaacct acatatttaa aaaactatac
    88561 acttgcattt attgtaggtg gaattatttg tatgataggg caagcaataa atgatttgta
    88621 catgaaagtt ggaggtcttg ataaattagg tgccagttct gcaacatcaa taacattaat
    88681 atttataggg gcatttttaa ctggattagg agtctacgac ctaataggaa aaagggctgg
    88741 agctggttct ataattccaa taacaggttt tgctaactca atagtatctc cagcaatgga
    88801 gtataaaaga gaaggctatg tattaggtgt aggtgcaaat ctatttaaaa ttgcaggacc
    88861 agttttagtt tatggtatag gttcttctat tttatgtgga attatttatt atatttttaa
    88921 gatgttttag atgattttta tttaatttaa attttattaa ttatgaagaa tgtataaaat
    88981 ctgaaaatag ttactaaagt agctagttga gagataatca tgcatattta attaatatta
    89041 aaaaattaaa tagtaaaatg caaaattaaa aaggtgtgaa aatatgaaaa ataaaagaat
    89101 tggaaaaaga acagtcaagt tagaaaataa accaacaata atatcaactg gaactatagt
    89161 aggtcctaag gaaggtgaag gaccactaaa agactatttt gatatgatta tgaccgacga
    89221 tttatatggt gagaagactt gggaattagc tgaaagtaaa atggtagaga ctgcatctca
    89281 acaagctata caaaaggcag gtaaaaaatt gacagatgta aattatatgc taggtggaga
    89341 tttaataaat caaatagtgc cagcatcatt tgcagcaaga gaactggcca ttccattttt
    89401 aggtatatat ggagcttgtt ctacaatggc agaaggtctt tgtataggtt ctatgcttat
    89461 agatggtggt tttgcagact tagtactgtc agggacatca agtcattatt gtacagcaga
    89521 aagacagttt agattcccgc tagaacttgg aaatcaaaaa ccaatgacag cacagtggac
    89581 agttacagga gcaggaagtg tattactagc tcctaatgga gaaggaccaa aggtaaaata
    89641 tgttacagtt ggtaaagtaa tagatgaggg cattgatgat ggcaataata tgggaccagc
    89701 tatggctcca gcagcgatag atactatcta ctcttatttt gaagatacta atgatgaccc
    89761 aaatagcttt gatataattg ctactggaga tttaggtact cttggaaaac agatagcaga
    89821 agatttttta aaagaaaaag gtatagatat atcgaaagtt tatactgact gtggtataga
    89881 gatgtttaat cttaaagagc aagatgtcca ttgtggtgga agtggatgtg gatgttcagc
    89941 tacagtattt gcaggatata tatatgataa gttgagaaaa aaagaattta acaaagtaat
    90001 gctcgtatca acaggagcac tactttcacc aacaagtaca ctacaaaagc agacaatacc
    90061 atgtgttgct catgcagtag taatagtaaa tgagtaggaa gtgatatata tgttaatgga
    90121 ctatgtaaga gtatttattg taggtggaat tatatgttta atagcccaag taatgatgga
    90181 ttattttaaa atgcaaactc catatgttat ggtaacgtat gtaacaactg gtgtagtttt
    90241 aactttttta gggctttatg agccattagt taagtttgca gcagcaggtg caacagttcc
    90301 tataatagga tttggatatt cacttgctac aggagtaata aaatcaatac agagtgatgg
    90361 ttttttaggc atttttctag gaggtacaac tgctacggct ggtggaatag cagcagccat
    90421 attctttgga tatattatgt cagtcgtatt tactccaaaa gcaaaaccat aaatctttat
    90481 ttaagagaat aataactttt agaaataata actttttata aagtaggtgg atatcttata
    90541 gattccacct attttttata taaagaagcg tttacataat tgaagttgac aattatttac
    90601 aacatagtgt agtattatat tatcaaaata aaatgaagtg aagtagggga taaagatggt
    90661 aactattaaa gatattgcaa ggaatctagg tatcagttat tcaaccgttt ctaggtgttt
    90721 aaacaataat cctaatgtat ctgaaaaaac aaaaaagaaa gtagtagaag aggcaaatag
    90781 actagggttc cattttaatg taaatgcaag aaatctggca aaaaaagaaa ccaacagaat
    90841 aggggtaatc ttttcaaata attttaatca tcaagatact agaaaatttt ttagtgatat
    90901 aatggacagc tctataaatt ctattgagac taataaatac gattttataa tacaaccgaa
    90961 taataacatt agtggtgata gtaatgtata taaaatggta aatggacaaa tggttgacgg
    91021 attagtaatt gtgtctcaat caataaaaaa agaagagtat gattttttaa aagacaataa
    91081 ttttccacat gtatttatat attttaaacc atcttttata ggagaagtag acaatttctt
    91141 ttgggacgat aacgtatatg gaggttatat agctaccaaa catttaattg accatggtca
    91201 taaagatata ataacagtaa cttcagatga taagagttca aaaatgcatg aagatagaac
    91261 caagggatat ttgaatgcta tggaagaggc aaatttaaag actgaagtca ttaaatctaa
    91321 aatggatttt gaatctcaag ttgaattttt agaaaaatat attgataaaa taaaaaaagc
    91381 ttcagctatg tttgtacaac aagatgtacc agcgatttct ataatacaag aattaaaaac
    91441 tacttatggt ataaatgtac cagaagatat ttctataata gggtataata atattgaatt
    91501 aatatcatac ttcaggtcgc atttatcaac aatagatgac ccaagagagc aagttataaa
    91561 aaatggagta gacagtttag taaatataat aaataaaaaa agcacagagc atattccaag
    91621 aaaactatat ccaaggttaa taatccgaaa tagtgttaaa agaataaaat agtaagtttt
    91681 taagcattaa aattttataa aaaatattat agattatgtg aagtgttttt acaaataata
    91741 taaataaaat taaaaggagt aggtgtatat aagtacattg tactccttta tttattgaga
    91801 gaatttttat aatatgaatg aataatttta ttcaattatt tgaaaatcta ttattttaat
    91861 aatgcaaatt aataaattgt ttgcatttta tatcatgaat ggataatatt tttttgattc
    91921 ataactaaaa gtatataaaa atgatgaata aatatatatt atacattatc aatgataggt
    91981 tatataataa aatcactaac aattatatta taagaaaatt ataaaaatta caaggaggta
    92041 tagaaatgaa agaaaaagca gggattagaa atgccataat agcagccttt ataatcacaa
    92101 tattggcaga attaattgga cctatttcat ttaaagttat gggaattaat gtaactttac
    92161 ttagtatact atgggctata ttcataggaa tggctgtttc tcctcattta ttagggagag
    92221 ttataccagc cttaaaaaaa tttatagggg ataatgaaat aaatgtatct ccatatttat
    92281 tgtctttaac actatatcca ttaggaataa tgtttggaat taatgcaggg cctaaagttg
    92341 gtatattact tcaagcagga ccagcacttt tattacaaga atttggtcat atgggtacaa
    92401 tgttgatagc attacctgtt ggagtagcat taggtcttgg aagaagtgca ttaggtggta
    92461 ctttttcatt atgtcgtgat acagcgctag gaattattgg agataagtat ggattaaatt
    92521 caccagaagg gataggaaca ctaggaactt atataagtgg tagtatattt ggaacattat
    92581 tattttcatt tttagcacca gtgggtgtgc ttttaggatt tcatccatat gctttagcaa
    92641 tggcatcagg aatgggtagt ggttcaatga tgggagctgc aacagcatca ttaatgaata
    92701 cagttccaca aatgtcagag cagattttag catattcagc gactagtgga ttgattacag
    92761 ctgttactgg aatatatata gaattatttt tatctttacc agtagccaac tactattata
    92821 gcaaagtagc tccagttatt gaaagattta gaggaagaaa aacagcaaga acaagtaata
    92881 aattgtaaag gaggatatat atatggaaaa aacttttaag accattatgg aacagataaa
    92941 aatagtattg tttatatata ttattatttg ctttggacaa atgatagcac ttaagactca
    93001 ggctcaggat ttattgattg gaagtgtatc tggatttttg ttggtgataa ttgctattat
    93061 aataaagaat tttgttaaaa aacctaattt accaggtttt gcatgggcta cattagttgc
    93121 atttgtatta tcacttccaa tatctccagt gggggatatc atagcaacga atgtaggaaa
    93181 aattaatttt atgtctacag taacaccatt attagctttt gcaggaatct ctgtaggtaa
    93241 ccaattagat atattaaaga ctttgagttg gaagttagta gttatatcat ttatagttat
    93301 gacatctact tactttggtt ctgcttttat atctcaaaca gttttaaaat taaatggaat
    93361 gctttaagga ggtagtaaat atgaatgaat taaaagtaaa aattaaagag gaaataaagt
    93421 tattgtctga agaaaaaaag acatcatttg aaaaagtttc tgattattta ttttcaaatc
    93481 cagaattagc atttgaggag tataagtcac aaaaagcatt atgtgattta ttagaagaaa
    93541 atgagtttaa tgtaactaaa ggtgtaggag gattagaaac atcttttgaa gctgtttatt
    93601 caaatggaac taatgggaaa acagttgctt ttttagctga atatgatgca cttccaggaa
    93661 tgggacatgc atgtggacac aacatcatag ggacaagttc tgttggtgca ggtatcatat
    93721 taaaagaaat catgaaaaaa cataatatag aagggactgt aaaagttttt gggacacctg
    93781 cagaagaaag agtaggtgga aaaataacta tgattaaaga gggtgtattt aataatgtag
    93841 atgctgcatt aattttacat ccaagtgatg cttcaatgcc tgatgacata tcatttgctc
    93901 aagttaattt aaaatttgat tttagcggta aggcatcaca tgctgctgct tttccttggg
    93961 aaggaaaaag tgcattaagt ggagtaatag cactatttaa tagtgtaaat agtatgagat
    94021 tacatcttaa agattatgca agagtacatg gaattataac tgatggaggt agcatacata
    94081 atataattcc tgaaaaatct acagctatat ttaatgtaag agctttaagc atagaatatt
    94141 taaatgagat ttgtgaaatg cttaaaaatt gtgctaaagg agctgcaata tctactggaa
    94201 ctagtgtgga aatagttcaa ttagatgaaa tatacaaaga gattaagaat gattctgaat
    94261 tagtgaatat agttagacaa aattttgaag ttttgggtga agactatgtt gaaagagatt
    94321 taagtcaagg tataggttca actgatacag gaaatttaac tcatgagata cctgcaatac
    94381 aagcgtatat caaattaaaa gaaaatactg caactcatac agatgaattt gctgttgcag
    94441 ctggtgggga agaaggtaga gtagcactta taaaagcaat taaggtgcta gcaatgtgtg
    94501 gagtagatat tttgtatagt aaataatata taattttaaa atatattaag aaaggaaatc
    94561 aaattagaca tgatattaaa acaagtaata gaggtttatg acattttaga taaagcagat
    94621 gctaatgggg aagaagtaaa aacttattta caaggttatg gtgaagtaga tgtaactgta
    94681 aaagaattgt cttcaagtaa aggctcaaca gatttagtaa agcttacaat tcctggtaaa
    94741 aatggaaaat caaaaggtgg agatgctcct actcttggta ttttaggtag actaggaggg
    94801 attggagcac gaccagaagt tataggtttt gtctcagatg gtgatggagc attggtagca
    94861 attgcagtgg ctgctaaact tttggatatg caacgaaaag gggatatatt agatggtgat
    94921 gttgtaattt caactcatat ttgcccagat gctccaacta aagaacacta tcctactcct
    94981 tttatggatt ctccaattga tatgatgact atgaatgaaa atgaagttga tagtagttgt
    95041 gatgcaatac tttctataga tactactaaa ggaaataggg taatcaatac tagaggattt
    95101 gcaatatcac caactgttaa agagggctac atattaaaaa ctagtgataa ccttttagat
    95161 attatgcaga ctgtaactgg gaagtctcca tttgtattcc ctttatctat tcaagatata
    95221 acaccatatg gaaacaatct gtatcactta aatagtattt tacaaccagc agtagctaca
    95281 gatgcaccaa tagtaggggt agcaattaca acagagatgc ctgttgctgg atgcgctaca
    95341 ggtgcaacta attttagtga tttagattca gctggtagat ttgcaattga agttgccaag
    95401 ctatttggta gaaataagtg tgatttctat gataaagaag agtgggaaat gcttattaaa
    95461 agatatggta aattaaatag atttcagaca tttggtatac agtagttaga aaaatgttaa
    95521 gtttatataa tttgtgatat aaatatttac aatatataaa caactagaaa taaaagatat
    95581 agtttaagac ttaaaaaata aaatatttat ttgattacat aaataaggag agttctattt
    95641 aggtaaaagc caataaataa gtataacatc aaaactaact taatggttta tatgcaggat
    95701 tgagacgaaa cagtgcgtat tgtaggaaaa tggtatgcac tgttttttcg ttctgttatg
    95761 tattagaaca gcatttcaaa ttccatatct gctaatttta tatattgctc ataagcgaga
    95821 tacttaccaa attaattgca atgttaataa tatcttgttt tgtaacaatt ggttttggtt
    95881 gcatttttct atccttcttt tggtaattta tgttgttcaa ctaatattat cgttgtagca
    95941 aagacatata aatgtgtcaa taaacatcaa agaaaagcta caaacataga gtataatata
    96001 ctttatcaga tttctctttt ttatgaaaat acataatata atttaattat aaaaaaagga
    96061 gtgtttcaaa gtgatttttt ttatcacttt gagacaactc cttatatttt tattcaaatt
    96121 ttatttttta ttaagttgct ggagttccac caccatcagg ggtattagta gagccaccac
    96181 cactatttcc accattatca ggaggagtag tagagccacc accattgttt ccgccattat
    96241 caggaggagt agtagagcca ccaccattgt ttccaccatt atcaggagga gtagtagagc
    96301 caccaccatt atttccacca ttatcaggag gagtagaacc gccaccatta tcaccagagt
    96361 tattattgtt attattattt tcttgttgtt gattattatc tggttttttt gtatcttcag
    96421 atgatggttg agaacttact ttagtaggag cagtaccttc aataaatgct gctttagagc
    96481 cagaagattg ctttcctcca tcatctaaat taatttttgt aaaatatacg tttttaggaa
    96541 cttcaaattc agtaactgtt aaattagcat gtattttttg catgactttt tcccatagtt
    96601 ttgcagtact agtacttcca tgtggtactt ctctacgttt tatagtgtta ccagaatcat
    96661 cttttctacc agcatcatct ccaatataag ttgcaccaac ataataagga gtgtaaccga
    96721 caaaccaagc atcatatgca ctatttgtag tacctgtttt acctgctaca ggcattccat
    96781 ttggaagtgc tgcaacacca ccagtacctt cagtaattac gctttctaac atatctgtaa
    96841 caacgtaagc tacttcaggg tctacaactt tatgttcttc aggagctttt ttaactaata
    96901 attgaccatc aaaggtagtt atagtagtaa aaatagaagg ctctacataa acaccttgat
    96961 ttgccaatgt accataagca gcagccattt gaagcggagt aataccattc gccataccac
    97021 ctagtgtcaa tgatgggaat tttctatcac ttgcttcaga tgaacctgag tgattatttt
    97081 ttaaagttgt tataccaaag ttctttaagt aatccatcat tatatctaca cattcatcat
    97141 aagagtctcc aagcatttca gcagtcttaa cagctattgt gtttgaagat ttagcaagtg
    97201 ctttacgtaa actcatagag ccatgaccag cagtagtagt tcttggattc catttattat
    97261 tttcttcaaa cttatatcct cctctagaat cacttagagc agttgattgt gttattttta
    97321 gagtatcaat agctggtgta tatattgcta aaggttttat agaagaacct ggttgatgag
    97381 ggttagtagc acgatttaaa gtttttctac cacttatatt tcttcctcca gctagtgctc
    97441 ttatttcacc atttttataa tctaagatta ccattgcagc ttgtggttgg ctaactccat
    97501 caggaccggc catatgtcct gggaaattgc tatttttatc aaactcttct tctaaagcat
    97561 cttgcatttt agggtctata gttgtattta caattaaacc accattatag aataagtttt
    97621 gagcctcatc atttgtatgt ccttgttcca ttaaagcatt tataacttca ctttcgataa
    97681 ggtcttctac agatgaagaa actttatctg atgatttagg caattttatt tctattttag
    97741 ctttgattgc ttcatcatat tcactttgtt ttatatattt caagtctaac attttcttta
    97801 aaacaatttc ttgtcttttc ttagcttcag gattacttac agcctttcta acaactaatg
    97861 tacctgcttt tagttgtcta taagtgtcac tagatataag gtcccaagat ttaatttttt
    97921 caatcatatc aaaatcaact tgagtagggt catctaaatc atcatcagtt gtgttaacaa
    97981 aaaataataa tttattttct aaatcctcct tagtttcatt tccctctaac ttagaagttt
    98041 tataggctga aaatcttgat ggatttttag ttgaaccagc aagaagtgct gactctgcta
    98101 gagtaaggtc agctgcagac ttatcaaaat aaccacgtgc accagcctca gcacctgcta
    98161 gacctctacc aacgaagaag ttatttaaat aagtttctag tattttatct ttacttactg
    98221 ttttactcat ctcatgtgca tagtaaatat cttttatttt acgaggtata gtttgttgtt
    98281 cagttgttaa caacattttt gatacctgca taggaatagt actaccacct tgcttagtac
    98341 ctgtaagggt ctttaatact gacctaaata aacctttaat gtcgacacct ttatgttcat
    98401 aaaaacgctc atcttctatt gcaattacag catgttgaag ataaggggaa atcttatcta
    98461 atggaacggg tgtcttttta tttacacttg gagctgtaga taatgttttt ccattagcgt
    98521 atttaattgt agttgtttgg tttgtctgtt tatctaaaac agcttctgta actggagtta
    98581 catctcttag tgatgcaaat actagaccag cagtacctgc tgtaccaaca actagtaaaa
    98641 ctaaaaatac tatcccaaat actcttagtt ttttaaattt atcgcttttt ttagattttt
    98701 tcttattttt tgttgaacga gttttgttag ctgaagttct attaattggt ttatttgtat
    98761 taccagatga gctaactttt tttcttctga ttttatttcc atttttatca ttatcgttat
    98821 tcataagatt tttaacctcc ttacttaatg caatattata acacaaatag gagtagtttt
    98881 gtaattaata gaaaaaatga atttgctata atattctgta cattgtatat gtataaacat
    98941 aatatattaa aaagtctata tttttatttt atttattttt gacaaatatt ataaaaatta
    99001 tgccaaagct acatataaat aaataggagg ggataatttt gaatagaata gtagatagaa
    99061 aaacaaaaaa tgaatttaga aaaattatag ctattttttt agtaattctt ttcttgtctg
    99121 tatttatagg cagttttata tatatagata aaactttaag accaacaata acagttttag
    99181 cagaaactaa agctcttgaa ttagcaaaca ggtctataaa taaagctgtt gctgagatgg
    99241 tagaaggaaa aataaattat gaagatttaa tggatataca gcttgataat aatggcaaaa
    99301 taactatgat acaagcaaat actataatga tgaatgaaat tgcatctgca atagctttag
    99361 aaatacaaga tgaattaaaa aaggataaga cagcaagttc ttacatacct ataggaacag
    99421 cattaggaag tcctatatta gctaaatacg gtcctaaact tgaagtgtct attgaaccta
    99481 taggaacagt atcagtaaac tttaaaacgg aatttgagtc ttcaggtata aatcaaacta
    99541 ggcatagaat atatttagaa gctcaaacac aggttaaagt agtaatacca cttataactt
    99601 caacaaaaca aattaaagct caaataccta tttgtgaaac tataatagta ggtgatgttc
    99661 cagaaagtta tgtaaatatt ccagaaaaaa atctaggaaa tgttttacct aacactggaa
    99721 aaaatactaa caagtaatat aaagttgtat atttttaaat aaattcaaag gaatagttta
    99781 taaataaaat ttttggaaat aatattaata taattttagt caaaatttat attttatact
    99841 atgtaaaata tctaatatat ttggtctgta ggttaaataa aattaccttt agaccaaata
    99901 tattattaat aacttaataa cgtcttaaaa cttatttatt tatattattt acaacatcca
    99961 tttaataaat acaccataac ctacagctgg gtcattttca attgcatgtg atactgctcc
   100021 gattatttta ttatcttgaa ctattggagt accactcata ccttggacaa taccaccagt
   100081 ttgagttaaa agctttttat ctgtaatttt aattttaaaa cttttacttt ctggatgttt
   100141 ttggttttct atatctataa tttcaatatt atatttttta cactcattaa agttatcttg
   100201 taaaattatt tgagcttttc ctaatttaac ttcatctaaa gatgctactt tatatttttt
   100261 taacttggaa atatcaaagt tattaatttg acctcttatt ccaaaatcag tattttctgt
   100321 aaagctacca ataatatttt ctcgttttgc atttatacat ccaacactac ctttataaga
   100381 tttttctata ttaaggtgct tagttgtaga aattgaacct gttttaatag gtatttttct
   100441 tgcattacca acacttattg gatgtcctac agctccaaac tctgatgtat ctggattgat
   100501 atacgttaaa gtggcaaatc cagaaagtaa attgttaaaa ctaatttttt ctaatatgtg
   100561 tttggttgtt ttcattgtta taagttgtcc acctctattt aataaaatag atacttgctt
   100621 ttcttctggt aaagcgttta aggtattagc aaaatcacta tatccatcaa cctcagcatt
   100681 atttaccttt actatagcat cacctaatct aaatggagat gcttctccag ggtttctaac
   100741 tatgatattt tttaattctg catcaatttg aagtacattt ccaattggta ttaaatattc
   100801 aggttcattt ttttgtaaat tttgtgcata aattaaatta tttgagaaaa aatataataa
   100861 aaataaaaat gttaaaacaa ttgtaaattt tgacttagct aagttggttt ttttacttaa
   100921 agtattatct ttaaaatgaa aatttttaag ttgcataaaa cacctctttc ttattaaatt
   100981 attttaataa tagaattgaa gttttcttgc tgcttctata ttatgttgtg caagaattat
   101041 gttttgatgc ttggaaaact gactcaataa caccttagtt ttcataaaaa taaataaaat
   101101 aaatagtgta tatgataaaa taaatacata ttcatataaa taaaaataaa caataactgt
   101161 ctagcataag aaaggagcaa aaaatgaaaa aatatagatt gttagttact tgtataattg
   101221 ccatgggaat cataattata ggaacatcaa atccagttag taatttttac aagactacaa
   101281 atttgattag ttcaggaaat atcacaaatg aaaaagcaga taaaggtgaa aattcaaaca
   101341 aaaataataa agataaagaa gaagacaaat ctaactctaa aagtaataaa gataagttat
   101401 cagaggacaa atcgtcagat aataaaaatg aaattcaaaa aaataaaaaa cttttaattt
   101461 gtatagaccc agggcatcaa ggaaaaggag atagcaattt agaaccagta gctccaggtt
   101521 cttcctctaa aaaagcgaga gtatcttcag gaacagaggg tattgctaca aaaaaaccag
   101581 aatatgtttt aaacttagaa gcatctcttg ttttaaagaa tatattagaa tctaaaggtt
   101641 ataatgtaat aatgactaga gagacgcatg atgtaaatat aagtaattca gagagagcaa
   101701 tacttgctaa tgataaaaaa gcagatatgg ttgtaagaat acatgcagat agtttaaata
   101761 attcctcaaa aactggagca tctatattga ttcctgaaaa agatggaaaa tataccgctc
   101821 ctatatatga agaaagtaat aaatgtgctg aatttatcaa acagaatatg gaacaatcag
   101881 gtatacaaat caatggaatc attcaaagag gtgatttgac tggattcaac tggtcaaaag
   101941 ttccagctgt attagtagaa atgggcttta tgagtaacta taatgaagac caaatgatgt
   102001 caaatccaga ctatcaaaga aaaatgatgc agtgtatagc tgatggatta gatgagtatt
   102061 ttaaatagag tatgaataga gaaaaaatta ggttggtatt attttcctaa tttttatctc
   102121 tattttttat tgtacataac acaaaagtga agtttatttt aggttaaatt gtcgtaaata
   102181 taactaaaaa tattggtaat gcttgattta agtttaaaaa gaatatatta tagtatagaa
   102241 tgtgtaaaat ttttttgaga ggtgttgaaa tgctagtagt agaaaatgtg agtcatggat
   102301 ttggtgcgag aacaatatta gaaaatgtat cctttagact tagaaaaggt gaacatattg
   102361 cactagttgg tgctaatgga gaaggaaaat cgagtttttt aaatataata acaaagaagc
   102421 ttatgccaga tgctggaaat ataaaatggt cttcaagagc tacagtaggc tacttagacc
   102481 aacatacggt attaagcaag gggaaaacta taagagaagt gcttagagaa gcatttaagc
   102541 atatgtttga cttagagcaa gaaatgattg ctatgtatga caaaatggga gaagctagtg
   102601 atgatgagat gagtaagctt cttgaagaaa cagcagaaat acagactata cttgaaaata
   102661 gtggttttta tatgatagat gcaaagatac aagaagttgc aaatggtctt ggtcttggag
   102721 aaattggtct tgataaagat gtaactgact taagtggagg gcaaagaaca aaagtacttc
   102781 ttactaaact tctacttgaa aatccaacta ttcttatatt ggacgagcct acaaactatt
   102841 tagacgaaga gcatataaca tggcttacta agtaccttca agactatgag aatagctttg
   102901 tcttagtttc tcatgatatt gaatttataa acaatacatg taatgtaata tatcatatgg
   102961 aaaatggaga gctaaataga tataaaggaa actatgatga atttgtaaga cttaatgata
   103021 taaagaaacg tcaagaagaa caagcttatg ataaacaagt tgaagaaaga aaaagactag
   103081 aggattttgt agctagaaat aaagctagag tagcaactag aggaatggct aacagtagac
   103141 aaaagcaact tgataagatg gaaatattag aaagaccaaa agaaaaaata aaacctactt
   103201 ttgcttttaa agatgctaga gcagctagta aaataatttt tgaaacagaa aatttagttt
   103261 taggatatga tgaagcattg acaaaaccac ttaatttcca tttagaaaga ggaaaaaaga
   103321 ttgccttaaa aggaatgaat ggtattggaa aatctactct attaaaaact ttacttggga
   103381 taataaaacc atttgaagga aatgttaaac taggtgacta tttagaagtt ggatattttg
   103441 aacaagagag ctcaagagaa aatagtaata cacctatgga tgaagtttgg agtgaatttc
   103501 cagggcttac aaactttgaa gttagacagg ctcttgcaaa atgtggactt acaaatgaac
   103561 atataactag ccaaatgaga gtattaagtg gtggagaagc tgctaaggtt agactttgca
   103621 aagtaatgct aaaaaatata aatttcttag tattagatga gcctacaaat cacttagatg
   103681 ttgaggcaaa agacgaattg aagaaggcta ttaaagagtt taagggaaca gttcttttgg
   103741 tatgtcatga gccagaattt tattcagaaa ttgttgatga tgtatggaat atagaagatt
   103801 ttacaactaa aatcgtgtag tgatttaact tttactgggg ggattttatg aaaaagtttc
   103861 taaatgtact tttttcagtt tgtattagta ttgttataat agtaggtgtt attaatttta
   103921 ctgttggatt taaaaaactt tattattttg acattgatta tttaaacata tcagagttat
   103981 ctggtttatc taaagatgat ataaaattga actacgatta tctaatcgat tataacttaa
   104041 ataagaatgt atcagagttt aatttaccaa cattaaaatc ttctccacaa gggaagatac
   104101 attttgaaga agttaggaat atatttcaaa atataaataa attagctaaa ttattgttga
   104161 tagtttcttt agtaggaatt atattgagtg taaaaaataa aaatataaaa atcttgaaaa
   104221 ctacatctat aacacttata atgatgccat tattattaac agttccaatt ttattgaatt
   104281 ttgaaaagtc atttattatt tttcataaat tattatttag aaatgattat tggatattta
   104341 atcccaattt agacccagtt ataaatatat tgccagagga attttttttt cactcaggaa
   104401 tgatgatttt aatattaatt ttattgtcaa gtattttact atttgtaatg tataaattat
   104461 gtaaatattt taaaataaaa taacaaaaac aaattatatt aaaggttata caataaaaat
   104521 agctatgtaa taatatttag gctaagagta gtcaataaat atttatgcat agctatttcc
   104581 aatagaaatt actttttact agtgatttta actaaatctt ggaattttcc cataatgtaa
   104641 ttgtaattat cttttttatg aggtaacatg caactactgc aatctttgat acctttatct
   104701 gtatacttaa agtttccacc acaattctct cctaaagcat acaaaggaca atagcaaaat
   104761 agacagttaa actcttctgg tttattagtt ttatgacaag ggaaaaattc acaatctttg
   104821 tgattaaaaa acttataatt ttcgcccata tcttcctcct aattaaataa aatttaaatt
   104881 ttttatacta tataagattt tggtgataat ataattatac taaataattt tatgaatagt
   104941 cgataatata gtattattaa tcatagtatt aatggtataa ttagtcaaca gaaaaataat
   105001 gtaaaagtaa tgtaagtgta ttttgtaatt agaatatgct ttataacaaa aaatgaggtg
   105061 attaagtgaa agaaattcaa gaaaaagcac ttcttgtagg tttgaatttg actacaatag
   105121 tgaaaaaaaa tgatgatata gacactagtg aatctatgga agaattaaag gaactaacaa
   105181 aggctgctgg ggcagaagtt gtaggtagct taattcaaaa taaacattct atagatgcag
   105241 cttattatat aggaaaaggt aaggtagaag aaataagagc gtatagtgat tctttagatg
   105301 ctactttagt aatttttaat gatgaattat ctggtgctca aatcagaaat atagagaatg
   105361 ttgttggtag aaaagtaata gatagaacta ctttaatttt agatatattt gctcaaaggg
   105421 cacttagtaa agaaggtaaa ttacaagttg aattagcaca attaaaatac agattaccac
   105481 gactttatgg aatgggtggt gagatgagta gaacaggtgc aggaattggt actagaggtc
   105541 ctggagaaca aaaactagaa atagataaga gacatatact taataaagca gcagatataa
   105601 ggcgtgaact taaagaagta aaaaagaata gagaaacaca gagagttaag cgtttaaagt
   105661 caaatatacc gattgtagca cttgttggtt atacaaatgc aggaaaatct accctgttga
   105721 acgaattaat aaagacacac aaggattatg aacaggaaaa ggaagttttt gtaaaagata
   105781 tgctttttgc aactttagat gtaaccttga gaaaggctct tttgccgaat aaaaaagaat
   105841 ttttagtagt agatactgtt ggatttgtaa gtaaacttcc ccatgattta gtagaagcgt
   105901 ttaaagcaac attggaagaa gtacagtatg cagatttaat cttacatgta attgatgcga
   105961 caaatactag ttatgaattg caaaaaagta cgactgaagg tgtattaaaa gaacttggtg
   106021 taaatgataa aaaacatata cttgtatata ataaagtgga caagctagaa ttggatatat
   106081 atcctaaaag tcaagaagat attgtgtata tttctgcaaa acaaggcata aatatggata
   106141 agttattaaa tatgatagaa attgctttaa tggaaaatac ttattcagta agcttgatgt
   106201 taccttatga gagaggtgat atatttagta gaataaaaga taaatataat gtggaaaatt
   106261 ttgagtatgg ggaaaatggt ataacgctag atgtagattt agatgaagaa gatttcaata
   106321 tctatagaga gtacatacta gaaaaatagg ttgaatatgg atataaactg ggaaaatata
   106381 gataaccttg aagattattt tataacctat cttctttata aagaatctaa aacagtgtct
   106441 caaattagta aaattagaaa tatttcaagt actgaagcaa gtgagcaact tatacaagca
   106501 aaattaaaaa taaaggaaat gcaaaaagat gattttgagg cgtctaagga tattttagat
   106561 aaatttttag aactagataa aattaagaga cttgatttta tggatagctt agacgacgaa
   106621 aaaatggtat actttaagag aaaggttttc aaaagaatcc ttgtagaaaa aaatgctgaa
   106681 gatttaattg ttttaatttg ggcgacaggt gagctaaaag atgatagatt tttgaaattg
   106741 cttcatcagc tcacaaacca cagacactca gatattagaa gaataactta ttcagcaatc
   106801 agaaagattg aatcaccaag tagtagagaa gtactacaaa aaggtctcta cgacaaaaat
   106861 gcacagacta ggcagtattg tgcaaaagct ctttcaaaat taggagatga aagcagttta
   106921 aaaattttac aacagttgaa agacaagaat aagaattttg aaaaagaata tgtgcttaga
   106981 gcttatgacg aagccattaa gtcattagaa aatgcaaaaa atttgaaaaa gtaatttttt
   107041 attaaagcaa tttgtttact taatgatgtt atttctaaag tttaacaagg taataaataa
   107101 attaatggga ggggtttcaa atgatagtaa gacgttgtgc aggtggagta gtgttttatg
   107161 ctaataaagt acttattgta aaaaatgata ggggtgaatg gacacttcca aaaggaaaga
   107221 tactaggagg aggtcttcca tatgagagtg ctgttcaaag agttaaagta gaaactggca
   107281 tagatgctaa aatgatagat gtggctggcg atactatgta tgaatttttc tcaagaagta
   107341 gacaacaaga agtttgtaat gcaataatgt ggtatgttat ggaagcttgt aacactgact
   107401 gtgtatttgc acctgaattt caagaaggtg gattttataa agtaaaggat gctttagaaa
   107461 tgttatcaca tcataaagag caagctttag tagaagtatc ttataaaaag tttaaggaat
   107521 taaagaaatt agtttcagag ggcgatgatg ttccagcaaa ttaattgtga atttagagga
   107581 ttctgaggaa gggatagccc cttccttttt taattgaagc agttttaagc ataaattata
   107641 tagcttgttt aagttatgat ttatcaattt agagctttag taatttacat ttaaaatcag
   107701 taagctatat ttaaaataaa aattaaaaag tatacaattt tattatataa ttgtcttatg
   107761 atattgatta aagaaatatt aaaagtccat ttattttttt atagaataat tttataaata
   107821 aatatgtatt tgatgtgtat attagaaaat gattaaaata ggaggaagta taatgagcaa
   107881 ttacaggaca ttacatgaat ttggaacgga tgaaataacg attgaaaagt ctgtttttat
   107941 tggatatgct aagcctataa agagtgaaga ggaagcctta gagtttataa atgaaataaa
   108001 gaaaaagcat aaagatgcga cacacaatgt gtgggcttat actgtaggta aaaatatgaa
   108061 tatacaaaga tatagtgatg atggagaacc acaaggaaca gctgggatac ctacattaga
   108121 ggttataaaa aaagaagatt tgagagatgt agtggttgtt gttactaggt attttggagg
   108181 aacaaaatta ggtgcaggag gtctagttag agcttataca aaaggtgcta agttaggact
   108241 tgaatcaggc aagataatct ataaggtaat gtatcaagaa gttaaggtta agatagacta
   108301 tactcaactt ggaaaagtac aaaatgagtt aatgaatttg gggtatttta taaaagatac
   108361 tatatatgaa gataatgttg agatagtagt atattcaaga ttagaagatg ttgataaatt
   108421 atcagaaaaa atgattgata taacaagtgg aactggaaaa atagttttag gagaggaatt
   108481 ttatttgtct gaacaaaatg gagaaatttt actataatct aaaaggttat tgtaatagtc
   108541 aatatcttaa ataattaatt ggtattttta agtaaaaagc cattaaattg atttaaccta
   108601 aatcaattta atggcttttt attagatttt gcacagaatc ctttttttac ttcaaataaa
   108661 ccaactaaaa gtaaaaatac cccaaatatt ttttttaata tatctgaaga tagataatta
   108721 gctaatagtg aaccaaatac agctcctaaa accccaaaca cagctatagg tataaccaat
   108781 ttaaaaatta catttttatt ttttatatgt atagcaagtg ctataagtgt catagggata
   108841 gatgaaagta aatttacgct ttgtgctatt ttagtgtcta tgccagcaag taaaacgagt
   108901 gcaggtataa ggattgttcc tccacccatt cccattcctc caataattcc tgcaaaaaat
   108961 ccaattagag caaataacat taaaacacca tccttaatgc tgcaattatc ataattattc
   109021 caaaagaaat tctaagaaac tttccagtaa ccttatttaa taatttagct cctataatac
   109081 caccaagaat acttccgact gcaactttaa ttgttaaatt aacgtcgtaa gtacctttag
   109141 atacatataa aacagaactt gttgtcgtta agaatattat tatagaaaga gcagttgcat
   109201 gagatttatg ttcttctacc ttaacgatat catttaatat tggaactaaa agagtgcctc
   109261 ctccagaacc aaaaactcca tttataaatc ctgtaaaaac tccaattatc gtatttttta
   109321 agttaaaatc aaagtatttt ttctttaaac catcagtttt tttcataaaa atcacccttt
   109381 gaaatagttt taccaaaata ggcaaattat atttatataa aataagatta aatataatct
   109441 ttcatatttg tttaattttg cataaaaaaa acatattaaa acaacatatt aatatatggt
   109501 ataatatatt aaaacaaagt agcaaatttg agaggagata acaatgtcaa atataaaaat
   109561 acaaatagac aaaactgtag aatggcttat aaataaggtt aatgaggcaa atgcaaaagg
   109621 attaattgtt ggtgtatctg gaggaattga ttcagcagta gttgctaatt taattaaaaa
   109681 ggcatttcca gaaaactcta tgggagttat aatgagcata aaaagtaatc ctcaagatag
   109741 agaagatgca cttaaggtta tagagggatg tgatatagaa tatcttgatt tagaccttat
   109801 agaaccacaa agtgctatat tagacatggt agtaggaaat ttaaaagata aacatttata
   109861 tagagaagaa tatttaaaga tgacagatgc aaacttaaga gcaagagtaa gaatgagtac
   109921 tatttataca attgctaaca atctaggata cttagttgtt ggtacagaca atgctgcaga
   109981 aatacacaca ggatatttta ctaaatttgg tgatggtgga gttgatattt tacctattgc
   110041 aaatttaact aaaggagaag tgtatgaatg ggcaaaagag cttggtgttc atgaagattt
   110101 aataaacaaa gctccttcag caggtctttg ggaaggtcaa acagatgaag atgaaatggg
   110161 aactacttat aatatgatag atgctgtgtt agaaggcaga ttggatgaag ttcctaaaag
   110221 agaccaagag ataattgaaa gacttcatag attaagtgaa cataagagaa aaacgccttc
   110281 acaacctcct aagttctaat ttactattta taagatttgt gataaaattt acaagtgatg
   110341 aaaattagaa taattaattg tacgtattaa ggagtggaaa tatgggacgt ataggtaata
   110401 taattaatag aaaaggtaaa caagatgctc aaagagcaaa gatatttact aaacatgcta
   110461 gagcaatagc agttgcagct aaagatggtg gagcagaccc agagtacaat gcagcgttaa
   110521 aaacagctat agaaaaagct aaggcagaca atatgccaaa tgataatata gatagagcta
   110581 ttgctaaagg tgctggagca ggtgctggag aagactatga aactatagtt tatgaaggat
   110641 atggacctgg tggagttgct gttatagtag aaactttaac tgacaataaa aacagaactg
   110701 ctggtaatgt aagatactat tttgacaaaa acggaggaaa cttaggaact agtggatgtg
   110761 tgtcttttat gtttgataaa aaaggacaaa tattagttgg tttaggagat ggagtttcag
   110821 aagaagaatt gatggatgtt gcattagaag ctggagctga agattttata acagaagaag
   110881 atggttatga aataataact acaccagaag atttttctag tgttcgtgat gagttaaaag
   110941 ctaaaggata tgaatttata tctgctgatg tgaagatgat acctcaaact acgactgtat
   111001 tgactgaaga atctcattta aaaatgatga ataaattagt tgatatgctt gaagaagatg
   111061 atgatgttca agatatatat cataactggg aagtagaata gatagtataa gtatattgaa
   111121 gtttataagt attgcattaa ttttaatatg tgataaattt tataacatat taaattacta
   111181 aaataaacat atacacctct aacctatatt tgcataatag gtaagaggtg tttttatatt
   111241 tataggttaa gaaatttaaa agaaaacgga gttatttgat ttagaataat atcaaatgag
   111301 attaacttaa cattgcaaat caaatctaaa attgtcagaa acgtttaaga tgggaaaagt
   111361 tacttagaca ttaagtcttt gtggtttttc ctatttttat tgataaattt gtactattag
   111421 aatagatata tattgaacta aagtattaat gatttaagtc aatagaaaat aaattatcta
   111481 ctatgttgaa taaagattcc ttatattaga gtgaagtaaa cttatagata tactgcttaa
   111541 aatattttaa tagaaatatc aaaaatgaga ctgcattctc aaaaatgaga ctgtgttttt
   111601 taggtatttt ctcgaaaatg agacaaaaat attgttttat gagttttatt gaagaaaaat
   111661 tcttttttga attacaattt aatcaatttt aaagttaaaa attattaaaa atttagtgaa
   111721 atttatgtat atttcgttta ttttattaaa aataaagagc ttcactggtg attggcatag
   111781 tacttgctat tttatattaa caagaaatgt agaaaaaata acaatgtata atggggggaa
   111841 tatgatggaa tctataatgg aaaatttgaa caatcttaag gtggaggtta aggacaaagt
   111901 ctgtgttatt actataaata gacccaaagc tttaaatgct cttaataatg acacccttag
   111961 ggaactatca caagttattg atgtaatatc agaaaatgag gcaatattag gagtcattat
   112021 tactggagaa ggtaaagttt ttgtagctgg ggctgatata cgtcagatgc aaaactataa
   112081 aagtgaggaa ggcagaaaat atgcaggtta tgctcaggga atttttgata aaattgaagc
   112141 tcttgagaag acagtaatag cagcagttaa tggatatgca ttaggtggtg gatgtgaact
   112201 tgctatgagt tgtgatatta gaattgcatc agaaaaggct atatttggac aacctgaagt
   112261 taatttagga gttattccat gttttggtgg aactcaaaga ttatcaagac ttgttggaac
   112321 tggaatagcc aaagagttaa tttttacggg gagacaagta aatgcagaag aagctaaatc
   112381 tattgggctt ataaataaag tggttccaag tgatttactt ttagaagagt ctataaagat
   112441 gatgaatcaa atagttgaaa aagcgccaat agcaataaga tatgcaaaag ttgttattaa
   112501 caaggggata gatatggatt taaagagtgc tcttgaacta gagaaagata ttgcaggttt
   112561 aacttttgct acaagagata agcaagaagg aatgaatgca tttatagaaa agagaaagcc
   112621 agtttttgaa aataagtagc tattacaact aaattggaac aatgtagaat atattcaaaa
   112681 tctaaatttc gtgaaaaaat acatatagtt taattttaaa aggagttaat ttatgaatac
   112741 gggagtaatt ataagtttag tagggattat catagctcta tctcttctag ttgtaatggt
   112801 tatgaaggga atcaatattt ttataatagc aattgtatgt tcatcattag ttgctataac
   112861 aggaagtcta aatgtgtatg atgcgcttaa ggtggattat atgacagggt ttgttggatt
   112921 tcttcaggcg aatttcttta ttttcctaac aggtacatta atgggaaaaa taatggagat
   112981 tactggtgga gcaaagtcta ttgctaagat gattgtaagg tggattggga aggataaagc
   113041 attactttct attccaatag cttgtggaat cttagcctat ggtggagtaa gtgttttcgt
   113101 tgtaagtttt gcagtgtttc cgatagcttt agaaattttt aaagaagctg atttgccacg
   113161 aagatttata ccagcagcgt tgacttttgg atgttcaact tttgctatgg ttgcaccagg
   113221 cgcaccacaa attcaaaata ttgtcccagc ctcgacattg gggacagata ttatggctgg
   113281 agcagtaaat ggttttatat catgtgcagt aatgtttgta gttggaagca ctattttgta
   113341 caaaatggtt tcaaaagaaa aggccaatgg tggtcatttt atagcacatg aatcagatgt
   113401 atttgatgaa tcagaagcaa ctaattctaa gaaagaaaat ggtcctaatg gtgtaattgc
   113461 gttaattcca ttaataatat caattttaat aattaatgta aaaattaatg gacaagcaat
   113521 agtaccaatt gaggtaggag tatttattgg agctttatta gtgtacttat tgttaaataa
   113581 atatcaagat aatgctaaaa tagttggaca tgttggtgat gcatgtaaaa ctacagtagt
   113641 agcaatatgt aatacttgcg ctgtagttgc atttggttca gtagtaaaat cagcagttgg
   113701 ttttgacttc atagttaatg ccatgactaa tattcctggt cctcctattg caggcgctgc
   113761 agttggaact acagttattg caggtatctg tgggtcagct tcaggtggac taggaattgc
   113821 agctccactt cttggaccag tatttttagc taagggtgtt tctgctgcag cattaactag
   113881 gactatggca atttcatcag cagcattaga ttcacttcca cacaatggat atatcgttac
   113941 tgtaacaaat ggtctgtgta aagaaacaca taaggatgcc tatatgccaa tattctgggt
   114001 aactgtttta actccgttta ttggaaccat agtagcagtc ttactgttta caatgttccc
   114061 aggattacca taagaaagaa gataaaatgc ataaattata ttttgatatt gtaaaattaa
   114121 ttttcaaagt atatacaata aatttcatgt tttaatactg taagtttgta tttaaaataa
   114181 caaaatgacc atataaggag gaattgaaag tgttaaataa accattagaa ggagttaagg
   114241 ttattgactt aacgtatttt gtagcaggtc caggaacttc taaaatatta gctgactggg
   114301 gagctgatgt tattaaggta gagccaagct ttggagaccc aggaagaaag acaggagcaa
   114361 caatgacaat gccaatagat gattataata atccttttta cagtacatat aattcaaata
   114421 aaagaggtct atctataaat cttaagagca aagctggaat tgaaattatg gataaacttt
   114481 taagtgaagc aaacgtattt gtttcaagtt atagaaccgg agcattaaaa agactaggtc
   114541 ttgactatga atcattaagt aaaaagcatc cacaccttat ctggggtcag ataaatggtt
   114601 ttggcgactt tggacctgct aaagataatg caggatttga tacagttgcc ttttgggcaa
   114661 gaagtggagc tatgcttgat atagcagaaa aagatacaag cccaataaat ccacctatag
   114721 cttttggaga tgcaacaacg tcttgtagtt tatctggagg aatatgtgca gctttgtacc
   114781 agcaagctaa gactggaaaa ggacaaaaag taatggcatc tttatttgga caagcaatat
   114841 ggaatgcatc atctttatta gcatctacac agtttagcga tgagtatcca aaaactagaa
   114901 aaaatgctat ttctccagta ataaattctt atcgttgtaa ggatggaaag tggatattct
   114961 taagtatttt agagcatgaa agatattttg aggcactttg tagattattt ggtagagaag
   115021 acttaataaa agaagagaaa tttgcttctt cagtagagag taagaaaaat gctacagaac
   115081 ttattaatat tttggatggc gaatttgcaa agtttactca aaatgagatg gttgaaaagc
   115141 ttactgctgc tgatatagcc catgaaaaaa ttcaacatgt taatgatgta gtaactgatg
   115201 aacaggctat tgctaataat tacatatatg agcatacaag taaaaatgga aataagacaa
   115261 tgcttgcatc tactccagtt aaatttggaa atattgaagt taacatgact tgtgatgctc
   115321 cacttatagg agaacattca gatgagatat tgagagaact tggatacagt gattctgata
   115381 tagaagctct aattgaatct ggaattgtaa caatgaataa agaagcatgt gaaatatgtt
   115441 aataaacatg cggagtatgt taataaatag gagggaattt tatggatttt agattaacag
   115501 aagcacaatt aatgcttcaa agagtagcaa aagaatttgc agagaatgaa atagcaccaa
   115561 tagctgctga aacagataaa acaggtattt ttccaaggga gctttttagc aaaatggcta
   115621 aaataggatt taatggtatt ggaacacctg tagagtatag tggttctggt ggagcagata
   115681 tagaaaaggt aattgttgtt actgagattg ccaaaaaatg tgcagcatct gcagcaatat
   115741 tatcaataca cacaatatat gctcaagcta ttttgaaatt tggtactgag gaacaaaaga
   115801 aaaaatacct tccaatgatg gctgaaggtg ggtgtgtagg tgcttttgct ttaactgaac
   115861 ctaatgctgg ttcagatgct gcaagagctg caacaactgc aattattgat gaagaaactg
   115921 atgagtatgt tttaaatgga actaagtgtt ttatttctgg tggaggtcaa gcagaatcat
   115981 taataatatt tgcactgaca gacccatcaa agggaataaa gggaatgtct gctatcattg
   116041 ttgacaaagg gactccaggt ttttcaatag gaaaaattga agaaaaaatg ggtattcatg
   116101 gttcagaaac tgcagagtta atatttgata actgtagagt tccaaagtct aacttattag
   116161 gaaaagaagg caaaggattt aacatagcta tgacctgttt agatggagca agaattggag
   116221 ttggagctca agctgtggga attgctgaag gagccttaga agaaagtatc aaatattcta
   116281 aagaaagagt tcagtttggc aagccgattt cagccttgca aggtattcaa tggtatatag
   116341 cagatatggc gacaatggtg gaatcagcaa aattgttagt atattatgct gcagacttga
   116401 aagctagagg agaaaaacac actaaagaag ctgccatggc aaaatacaat gcatcacata
   116461 ctgcaagaga ggttacaaat ctagctcttc aaatccatgg gggatatgga tatatgaagg
   116521 attatccatt agagagaatg tacagagacg ccaaaataac agaaatttac gaaggtactt
   116581 cagaaataca caaagttgtt atttcaagag cagtactagg ataggaggaa gagaatgaat
   116641 atagttgttt gcttaaagca agttccagat actaatgaag ttaaaataaa taaagagaca
   116701 ggtactctaa taagagatgg tgtaccaagt ataatcaatc cagatgatag aaatgcctta
   116761 gaagaagctt taaaaatgaa agatgaatta ggagcagtga ttaaggttat aagcatggga
   116821 cctcctcaag ctaaaagtgc tttaaaagaa gctttggcaa tgggtgctga tgaagcatat
   116881 ttaatttcag atagagcttt tggtggctca gatacttggg ctacatctac aattattgct
   116941 gctgctatag agaaggttgg gaagtatgat gtaatattct gcggaagaca agctatagat
   117001 ggagatacag ctcaggttgg accagaggtt gcagaatttt taggaatacc acaagttact
   117061 tatgcaaaag aagtaaaagt tcaagatgac aaattactag taactcgtta tacagagaca
   117121 ggagattatt taatcgaagc aaagatgcca gttttactaa ctgctataaa agagttaaat
   117181 aatccaagat atccaagtgt caaaggaatc ttagaagctt ataataatgg agatgcaaag
   117241 attaatgtgt taacacttgc agatttagat gttgacacaa ctcaaattgg attaaagggt
   117301 tcacctacaa atgtttataa gtcttttgta ccagttaaag acaagcataa tgaaataata
   117361 gaaggtataa ataaaaaaga aaaagctgag aaactaatag aaatactatt cgatttgaaa
   117421 ctagtatagg agtgttaaga tgatgagagc aaaagttaat caaggtataa atttaaatga
   117481 ttataatggt gtttgggtaa taggagagca aagagaaggc aaaattaatc ctgttactat
   117541 agaacttatt ggtgaaggaa gaaagcttgc tgaccaatta ggaaaagagc ttgcagttgt
   117601 gatagctgga tatgaagtag agaaagaggt gaaggaatta cttcactata gtgttgataa
   117661 agtatattat atcaatgacc ctcttcttaa agatttcact actgatggat atgcaatttc
   117721 aattgcaaac ttaatcgaaa gaaaaaagcc agaggttgta ttagttggag ctacttctat
   117781 aggaagagat atagcgccta gaattgcagg taaagttgga acaggtctaa ctgctgactg
   117841 tacaaaactt gaaatagatt caacagataa taagttatta caaacaagac cagcatttgg
   117901 tggaaattta atggccacta ttgtttgtcc taaaaataga ccacagatgt caacagttcg
   117961 cccaggagtt atggcaaaag ctgtaagaaa tgaatcagag actggaattt tagaagttgt
   118021 tactccagaa cttactgaaa aaatgattag aactagatta gtagagatac ttccacaaga
   118081 aaagaaatct gtaaatctaa ctgatgctag aataatagta tcaggaggaa gaggattaaa
   118141 aagagcagaa ggatttgagc ttataaaaga attggctgat aaattggggg cagagattgg
   118201 tgcttcaaga gcagcagtag attcagggtg gatagaacat tctcatcaag tgggacaaac
   118261 aggaactact gttagaccag aactatacat tgcatgtgga atatctggag caatacaaca
   118321 tttagcaggt atgagtgatt ctaaatatat agttgctata aataaagatg caaaagcccc
   118381 tatttttagt atgtgtgact atggaatagt aggagattta tatgaaatta tacctgaaat
   118441 gatagaatca ttaaataggt aacttctaga aaacattgaa tatgtagaat gataagtctt
   118501 ataatattgt attgtaagac ttattatttt tgctgaaggt tatagtgggg agatgaaaca
   118561 atgaaagaac agtggtataa ggatatattt gcaagagtat tatctatgac tgatgatggt
   118621 tttattgttg taaatacaag tggagtaata atagatatta atgataaata ttgtgacttt
   118681 ttaggaaaag aaagaaaaga tataatagga cacagtatac aaagtattat accaaataca
   118741 aaaatgttag acgttatgag agataagtac tgtgaagaag gagctataca tcattattca
   118801 ggtggaaata caaaagaaaa aagtgtgata gtaagtaggt cttatgtgga aaatgacaat
   118861 ggagaagtag ttgcaggagt agctcaagtt aaatttagat tgcaatcctt tgatgtggct
   118921 aaaaagttaa tgtcagaata tatggagctt caatattata aagaacagtt taaggataat
   118981 tgtggttttg acaagctcat aggtgaaaat aaagatttta tagaacttaa gaaaacaggt
   119041 gtgaaagctt ctaaaacaaa ctttccagta cttttaacag gtgaaacagg cacagggaaa
   119101 gaagtatttg ctagagcaat tcacaataat agcagtaggt cagacaaacc tatggttagt
   119161 ataaactgtg ctgcaatacc agaagaatta ttagaatcag agttatttgg ttatgatgaa
   119221 ggagctttta caggagcaaa aaaaggtggt aaaaaaggca agtttttagt tgcgaataat
   119281 ggtacaatct ttttagatga aataggtgac atgcctttga ctatgcaagc aaaactttta
   119341 agagttcttc aggaaagtga gatagaacca gtaggaggtc ttaaaaccat aaagatagat
   119401 gtaagagtaa tctctgctac aagaaagaat ctaagtaaaa tggttgaaga aggattattt
   119461 agagaagacc tatactatag attaaatgta ataaacattc atatgatgga attgaaggac
   119521 aggcaagatg atattttatt gttagcaaat tatatattaa acaaattaaa tgttgaatac
   119581 aaggaattga aggttctaag tgataaggtt aaaaattgtt ttattaatta tacttggcca
   119641 ggaaatataa gagaactaca aaatgtaata aaaagtgcct atgctgtaag tgatgatatg
   119701 gtcattatga tgtgtgacct tccatctaaa atggataata tcagtagagt agctcaatgt
   119761 aatgtggata gtaactgttc aattcatgaa atggttgaga attatgaaaa gagtttaatt
   119821 attgatgtgt taaggaagta caattggaaa tgttctaagg cagcagaggt tatgggaata
   119881 cacaagagtc ttttatataa gaaaataaaa aagtatgaaa ttgaattaaa taattaagat
   119941 gacttgaatt aaagcaatgt gcaaaagaat caacattata caaggtgaac tgtataaact
   120001 gttttaggta gttaaaatgt gcaaaagtag ttgtgaagta ctagtgtcaa tcattagtac
   120061 ttttttattg tatttataat tactatctat atttcattat cttttgatgt ctaagattat
   120121 tatgtttaat ttaggacaga ataaaaccct cttagttttg gacagttttc atattttaac
   120181 tgtctactaa gagggatagt ttaggtcaaa tttagagtga attttatcta gcatttataa
   120241 aaatattttg aataactttt ttgttattta atcataattt tctacttctt tatcaagttc
   120301 ctttccacaa gaatcacact tatatatagc attatatccg taatcatatt catcaactat
   120361 tttcttctgt ctaaatacac caccacactc acataggaaa ccaattttta taagtgtaac
   120421 gataaattgt gactttataa attttatatc attacatttg tcgttagtgt aaaatgtgta
   120481 aatataagag ttatcgcact catctcttaa ttcaaatttt tcaatatatg tgttattttt
   120541 taattcctca aattcttctt tagtcaaata tgatttttgt tgcaattcat gtaaacgttt
   120601 gatttggtcc attatttata tcctcccaat aattttagta ttttaagctt agataaggaa
   120661 tctaagtttt attaaattta tcctaaggaa ttatttaaat catatttagt tttattaatt
   120721 gcaacatata tatattatac aaaaataaaa ctaattgtaa aaataatatc ctgtgaaaac
   120781 ctaaactact aaccccttac taacccgaaa actaaaaaaa gaaaatatat ccaaatataa
   120841 gtgatatata aataaagatg ttttatataa atttaacttt aaatattctg acaataatat
   120901 atataaatat attatagtta aaatatacca catattttgg gtattgtata ctagaattag
   120961 attaattaat ttatttttta acatacaaat gattctgtga aaaaaaacaa gactcaaaaa
   121021 tttttatatt ctttgataga ataaaattga gagtaaattt attgaatttt ataaaattta
   121081 taaggggtga atgtaagata tgcatgaaga taaaaatgac atatttgaat caatagatac
   121141 tgaggatttt gataataaaa cagaagaaga atgtttagag ctagtaagaa aaaatggatt
   121201 gaatttaata tacataaaaa atcaaacaga agagatatgc ctagaggctg ttagacaaaa
   121261 ttgcaatgca ataaaatgtg ttcagaatca gacagaaaaa atatgtatag aggcggttaa
   121321 acaagattgg agaatgttag aatttgtgga agaaccaaca gaagaaattt gtatgttggc
   121381 tattaaccaa gatggaacag ccttaaaata catagaaaat cagacagaag agttgtgcct
   121441 aagagctgtt gaaaaaaatg gtactgcttt ggagtatgta aaagaacaaa cagaagaaat
   121501 atgtatagaa gcagttagaa atagtgaatt tggattggca agagtgaaaa atcaaacaga
   121561 aaaaatatgt atggaagcag ttaaacattg tagctataat ctaaaatggg tagaaaatca
   121621 aacagaagaa atatgtatgg aagcagttag gcaaaatggg cttgatttga aatttgtaaa
   121681 aaatcaaact gaaacaatct gtttaagagc agtaagacaa aatggattgg cattagaatt
   121741 tgtaaaagaa cagactgttg gtatatgttt aaaggcagta agacaatatg gaatggcatt
   121801 gaaatttgta aaagaacaaa cggaagaaat ttgtacagaa gctataaaac aagataaaag
   121861 ggcacttagt tttgtaaaag gagacaagga aaaatacaag gctctatgtg ataataatga
   121921 accatttgca aagcgatatg ttagaaatgt aatagaaaaa gaaaatagag cattgattaa
   121981 aaaaggtgaa gaaaatgcaa aaatcaaaat tgcaggaaaa ctttatgata gaggtatgtc
   122041 ttttgaagat atatcagata tagttgagat tgaaataagc aagttaaaag tgagcttagg
   122101 tattttttaa gctaatagat gtaggtgttt tttatgggaa atagttaata aaaaaataat
   122161 cgacgagttc tttgtagtac agcaaaatta gtgctataat ttgatatata ataaattatt
   122221 tttattagat aagggggaat taaagttgaa gattacaata ttataccaaa caagaagtgg
   122281 aaacacagaa agggtagcta agctgataga agatggagct aaaaaggtag atggagtaga
   122341 tgttaaactt atgagacttg ataatattga tttagattat ttaaatgaaa gtaaagcagt
   122401 aatatttgga acacctactt acttagcaaa tacaacttgg gaagtaaaaa aatggtttga
   122461 tgaagattca aaaaaagtca atttagctgg aaaattagga gctgtttttg ctacatgtga
   122521 ttatatatgt ggaggcccag atgttgctat acttactgta gtaggacatt tgatggttaa
   122581 aggaatgctt gtgtattctg gaggtggttc tttaggaaaa ccatttatac atttaggaca
   122641 tgtacattca attgaaggtc cagaactaca agatgagaag gctataatat ttggtgaaag
   122701 aattgctact aaggcaaaag agctatttaa ttaatttcta tatgcataat gatgattaaa
   122761 atatttaaaa tcaaacgtca atagtgaggg aagtttatgg tatggcatat agaatatgag
   122821 gttttttctg caattatagt tattttttta atggtatact tttttagaag caaatttata
   122881 cctactttac aaaacaaaat atattgtgca cttttaatat tctcattttt atttataatt
   122941 tcaaatattt taggttcatt ttgtctaaat aatatagaga aaattccaat ttttattact
   123001 tttttattga atcagatata ctcattgtta ttgccaatac cagcagcact tgtatcattt
   123061 tatgttatgg ctattattta tcaagatata aggtatatga aaaaaagatt attattttta
   123121 tctataccac ttttaatctg tataatctta tctattacaa atccttttac gcatattcta
   123181 tttggattgt caaaagaaac aggttatata cgaggttgtg gatatgttgc tactttttca
   123241 tcctttttct tttatgcaat atattcagca cttttatctt ttaaatatag aaaagcaatg
   123301 catgaatcaa aaatatgggc tattagaggt tttcttatag tttcaattgt ggcaattatc
   123361 ttacaggcaa tttttttaca gtatcttctt acaggaactg catgtgcatg tagtttactt
   123421 ttgacatatc tttctatgca gaatcgaggt cttattattg atgaccttac tggtgtactc
   123481 aatagacaat cttttattca agagctagat ttgaatatca atactgaaca atcgggattt
   123541 attattacaa ttgcacttga tgactttaag ttcatgaatg aaacttttgg aacaaaaaat
   123601 ggagatattg cattaaaaga agttggaaaa tatttggttc atatacatga tgtaaaccat
   123661 gtatatagaa tagggggaga tatattttct attgttgtca atagtcaatt aggtataaaa
   123721 ccagaggacc tcatcaaaaa gatagaagaa agatttaaaa aaacttggct agtagaagag
   123781 ataagtttta atttagcaac tagcattgct gttgtttatt acccagaaaa tgcagaaacg
   123841 acagaagatg taattgttgc tatagatttc tctatacatg aagcaaaacg ttctgagtca
   123901 aggcgagttg tttatgcaga tgcgtctata agtgaaaaga taaagagaaa acatgtgatt
   123961 aaaaattgtt tagaagaagc attaaaaaat gatggatttg aagtgtatta tcaacctata
   124021 ttttctaata gcagaggtag gtttacttca gcagaggcat tacttaggtt ggaacataaa
   124081 gagttaggtt ttataccacc tgatgaattt attacaattg cagaacaaac agggttgatt
   124141 aatttaattg gattagtagt ctttgagaag gtatgtagat ttatagccag tgatgagttt
   124201 gaaggtttaa aattggataa tatagctgtg aatctctctg tagtacaatg tatgcaaaaa
   124261 aacttagctg atgacttgct ttatcttatg gataaatata atatatcacc aactaaattt
   124321 aaacttgaaa ttactgagac agtagctatg ggatctttta atataattaa agaaacaatg
   124381 gaaagattaa ttgatttagg tgttaagttt gcacttgatg attttggaat tggttattct
   124441 ggagtttcta atatgctttc tttaccgttt tcagtgatta agttagataa gagcttgatt
   124501 tggtctatga atgaagacag tagacataag cttacagttg aaacgattat agctcttata
   124561 aataaattga atatgaaggc tgtagcagag ggagttgaaa ccataaaatg tgctgaagat
   124621 ttaatagcta tggagtgtga atacttgcaa gggtattatt tttctaaacc gattccagaa
   124681 gacgctttta aaaatttgtt gaaagaaaat gcttttacag gttaataccc tttatttttt
   124741 taattacaat tttgttcatt gacactgcca gttatatatt ataaaattaa cacaataata
   124801 aatattaaac ttattataca tattattaat attaattcat gaagtaaaga tttattatat
   124861 atttttataa cttagaatat atattttatt taattatcct aaagtgagaa aggaagatgt
   124921 gacatgaata aaaagaaaat attagtgcca attgatggga cagaaagaag tatgcattct
   124981 ttggaattta taaaaggaat attcaaaaaa gatgaagttg aagtagaaat aatgaatgta
   125041 aaagaactag tatttattga tggcatatcc ctggctgaag agataaaaaa ttctgaaaac
   125101 ttaggaagaa gaatcttgga taaagcagca gagataatgg gagagtatga tgttaaggta
   125161 cattttactt ttggatatcc aggagacgag ataattagaa aagcaaaaga agataatgta
   125221 gattttatag ttatgacaaa atctactaaa aagggtctta caagaatgat aggttcagta
   125281 acagcaagtg tagttaaaca agcaaaatgt atagtgatga ttgtaccgga gtagaattag
   125341 aaaggtattt gaaatatgaa taaaaagata gtagcagttt gtgaaagtga aagaagttta
   125401 aattctctta agatggctgc aaatgattta gggtttgact tagtttatga aattcaagaa
   125461 aatgataata taaaaaatga actttctatt tatgatatag aagacgcatc tatagtgtta
   125521 tttgttacaa gtgattctat agaaagtata gagaagattg atagatttat agatagagaa
   125581 ttttatgaag ttgatccaaa gtatataata gaggatgcaa agtctatagt aagtgaaatt
   125641 ttaatagact taaattaatt aggggtgtct caaaatgaac tttttagttc attttgagac
   125701 actttttttc tatgaaatca aatatatttt tatcatttca acaataaaaa tgtgattatc
   125761 tctattttga cacaaccctt tgagataatt catttttgta tgacagttgt gcttaggaaa
   125821 aatagaagtt taatcatcat gctgaaatag ctgaatgaca tcttctaaat gattgtacat
   125881 tgatgtataa cctaagttag agtctttact atcaaaggct attattatgt tattatgatg
   125941 gctaatcata tcttttagag aatttctata tttaaaacca aagtattgat tagaagaaat
   126001 tgttttaggt attaactcat aataccttat aaaaattggg ttatgagagg ctagaattat
   126061 ttctttgtga aattgtaagt cagcatcata acattcttct atcaaacctt gggagacctt
   126121 atccaattct tctattgatt ttaggtaagt atattttatt ttttgaattt ctttagatgt
   126181 agcatttaaa attgctagtc tagtagcttc actttcgata agttgccttg cccttaaaga
   126241 ttctacataa aattcttgga tgttatgatt tttatagatt tcaccatcat caaataggtc
   126301 aattttctta aatccttcaa ctataggact tgagtaaggc acagccctaa gtattccttc
   126361 cttacagagt atatttatgg catttcttac aggtattcta cttatgttaa ataggtcagc
   126421 aatctttctc tcacttggta atttactatt aattttaaaa gttccattta gaatgtttaa
   126481 tttaatataa tcaataattt tttcagtggc atttaagctt ttcataaaaa ctcctaaata
   126541 tataattttt ttatgattgt attatatcat agttaagagt taaatctaat tttttataat
   126601 atgtataaga taagatagaa gccactatag ctataatagc taagacaaag tatccatatc
   126661 gtattgaagt atattccgat attttaccaa ctatcattgg aaatacagac attcctatag
   126721 cataaattgc ttgaaaaaag cccattgcag tagacctctg atgttttggt acatttttca
   126781 tagactcgct agtaaggtaa gaaagaagta ttcctgtaga tatacctggt agcacttgta
   126841 gtacaaatat tatattgata ttttttattg ttggaactaa aaagcagtag gctgaaacta
   126901 aaataaaaac taaaggaatc caaaattttg gttcatactt agtacaaaat ttagtagaag
   126961 caaagccaga agaaataaca gcacacacca tgtaaaatat agaagataga cctataaggg
   127021 tagaactaga acctaagttt ttaagaattt gagtggtaaa tgacattgtt gtagacattt
   127081 gaataccttg ttgaattaat gccataaagg aaaaaaatat aagtctttta tccttacata
   127141 tagataagta ttttttaatt gatatttttt taggcatttt ttttgaatta tgatttttta
   127201 tatttaaagc tagaatcgtt ccaataactg aagacaatac actcataata cataaggctg
   127261 tcattcctaa tttttcataa aataaagtac tcataacaaa tccaatcaac attcctagat
   127321 tgtttaccag tattatcgta cttgtagctt tttgttgatg ttctttagaa aaaaaattgg
   127381 tatagtgaac catgtaagaa atccaagttg atgatgatat tccagataaa atgttagcta
   127441 gaagaaaacc attgccttca ggaaaaaata ctcttataag agatgccaaa ccagcaaaga
   127501 aaattccaga tagtataaat attttatgtt tatttattga atcagcaaat actccaacag
   127561 gaagtcttag taaacattgt gagattccat atgcacctat tattatacca atcatatttg
   127621 tagatacatt gcatgcactt aaatatggac tttggaaagg tatatataca tattgcgaaa
   127681 accagaaaaa cgtaacaata gaaagtaaaa gtaatttttg attagatgtt tttttcatat
   127741 tatcctccat atggtatatt tataatgcaa ataatatacc atttagattt tttaatcaag
   127801 tactttctct attaaaaaaa atttaaatat ataattatta tttacaaaaa aattataatt
   127861 tatagttgaa ttaagaaaac gcttatgata ctataaagtt aacaaatttg aatatataac
   127921 agtagacgtg ttactggtaa tgcaggcaag atcgaatcaa tttttataga ttatctatag
   127981 agtactatgg gtataatcta tttatttggt tcgatttttt tgtttaaatg gccataaaac
   128041 aaaaagccga taattgaaaa tggaggattt tttatggatt ataaaaatat agctcaagaa
   128101 attctactaa atgtaggagg aaaagagaat gtaaatgaag tgactcattg tatgacaaga
   128161 cttagattta aagtcaaaag tgcttctaaa gtgaataagg ataaattatc taaaattgaa
   128221 ggagtaataa ctgttgttga gagtatgggt caaatacaag ttgtaattgg caataaagta
   128281 aaaaaagtat atgacgaggt tataaaaatt gtacctcaat caaatgaagt aggtaaaaag
   128341 aatgaaagtg aagaaaagca aggtataatt aattctatat tatcagcagt agctggtata
   128401 tttacaccta caatacctgc tatagcaggt gttggtatga ttaaaggtat cttatcagtt
   128461 cttgctatgt attatatgaa taaaaatgga gtagatataa aagaaactca aagctatatt
   128521 attttaaatg ctatggcaga ttctatattc tattttatgc ctattatact aggatatact
   128581 gcggctaaag tatttaatgc aaataaaata atatctatgg tattaggagc tacactttgt
   128641 tatccaactt ttactgcttt gatggcaggt gaagaagctg ttagattttt aggcttggca
   128701 gtaacaaaag ctacgtatac atcatctgtt attccaataa ttattgccat atgggctctt
   128761 tcatatgttg aaaaagtatt agaaaagtat atacctgagg taatcaaaat aataatggtt
   128821 ccaactttat cattggttat aatgttacct gcaacattat ttttatttgg accaatcgga
   128881 atttatatag gaaatatcat aaacttttct tataagtata tttatgaatt aagcccagca
   128941 ttgtgtggag catttgtagg tggattatgg tgtgtgttgg ttatatttgg tgcacataga
   129001 gcgctattac caataggtat aagtgatgtt gctcaaacag gaagacaaaa tttattggca
   129061 tttgcaggag ctgcaaactt ttcacaagca ggagctgctc taggagtatt ctttaaaact
   129121 aaaaatcaag gactaaaaac aatttctatg tctgcaacta taacagcttt atttggtata
   129181 actgaacctg caatatacgg tgccaatctt agattaaaaa aacctatggt atgtgctgta
   129241 atatgtggtg cagttggagg tgccataatg ggaatgggtg gagcttatgg taatgcattt
   129301 gcaaaccaag gtgttttaac tatacccgta tatgctgaag caggtgcatt aggtttctta
   129361 agttatctag gtggctgtgc tatagcattt tttggttcag ctatttcaac ttatctagtt
   129421 ggatttgaag atttggaaga gtcttctaat aaggaaaatt catttataaa agtagaaacg
   129481 aaagatggtg ctattgatat aacttcacct gtggagggag aatgtataga attatcagag
   129541 gtaaaggatg acgtatttgc atctaaagct atgggagaag gtatagccat attacctaca
   129601 aaaggagtaa taacagctcc tactgattgt gaagtagctt ctttatttcc aacactacat
   129661 gcaataggat taaaactaga taatggagca gaaatgttaa tacatgttgg aattaataca
   129721 gtagagttaa atggtaaata ctttacaaaa catgtcaatc aaggagattt agtgaagaaa
   129781 ggtgataaac ttatatcttt tgatatagat aaaataaaaa aggctggtta tgatgtaact
   129841 acgccagtta tagtaaacaa tacatttgac tttggacaag tagtttcttg taaatctagt
   129901 tatgtttcaa ccaatgataa tataatttca ttagtattag ctggtaatta agttaatttg
   129961 actagagata agtaaattaa caattaaata catctaaaag taagtttatt gtaatgaatt
   130021 attaaaaaaa taattaatat agagtaaatt tattttaatg aagtaacaaa gaaaatagtt
   130081 aatataaagt gaacttattg taatgaaata acaaagaaaa taattaatat agaataaatc
   130141 tattgcaatg aagtaacaaa gaaaatagtt aatataaagt gaacttattg taatgaatta
   130201 ttaaagaaaa taattaatat agattaaact tattttaatg aagtacaaag aaaataatca
   130261 atataaaaag gagaaatatt tatgaataca ggatttccaa aagatttttt atggggagca
   130321 tcatcttctg catttcaagt ggaaggagct tgggataaag ataataaagg aaaaaccgta
   130381 gctgactata attcttttaa aaagtctcat ttacaggcag atactaaagt ggcatcagac
   130441 ttttacaata attatgaaga agatattgaa ttaatgaaag aattagggat gaaaacatat
   130501 cgtttttcaa tttcatgggc aagaataata ccagatggtg aaggagagat aaaccagaaa
   130561 ggtatagatt tttataataa gataatagac aaactaatag agtgtgatat tgaaccattc
   130621 gtaactttat accattttga ccttccattt acattagtag agaaatataa tggctgggaa
   130681 agtagagaaa ctgtctatgc ttttgaaaga tttgctaaaa tatgctttaa gcattttgga
   130741 gatagagtaa agtattggca acctcataat gaacagaatt taattgttag agtggaagag
   130801 agaattaata tatatgatga aacagattca tggaaaatag ataaaatgcg tgctcaaatg
   130861 gactataatc tttgtttagc acatgcatta gcagtcaatg catgccatga gatgataaaa
   130921 gaaagtaaaa ttggagcagc agtatcatca tctgtaacat atcctcttac ttccaagcca
   130981 gaagatgtat atgcagctag aatgaatgat aattttaaag tgtactatat gcttgatatg
   131041 catcactatg gagaatatcc agggtattat atgaggtatc ttgaaaaaag aaatatagtc
   131101 cctcatatgg aagatgggga taaagaagta cttaaaaagg ctaaaatgga ttttatagct
   131161 gtaaattatt atagaacaaa ttgtgcagga gccttcccag aggattcaca acatccattt
   131221 gggttaagag aaggaactgt tgattttagt atgtatggat tatttaaaat gtcaatgaat
   131281 cctaacctag aagcttctga gtatggagca gcaatagacc catcaggtct tagagttgcc
   131341 ttaaatgaat attggcaaag atatcactta cctgttataa taacagaaaa tggtcttgga
   131401 gctaaagaca tattagaaga tggaaaaatt catgatgact atcgtataga ttatttaagg
   131461 agtcatataa atgcatgtag actagctatt gaagatggtg tagagatgat tggatattgt
   131521 ccatggtcat ttacagacct tttaagctct tctcaaggtt ttaataagcg ttatggactt
   131581 gtttatataa atagaactga ccatgaagtt ttagatttga aaagaatcaa gaaagatagt
   131641 ttttactggt acaaagaagt tatagagaac aatggaatag taaaataaac ataaatatat
   131701 attgagggtt ttagtatgta cattacaaag gtattaaata attcgttgct acttgcaagg
   131761 gatgataatg atgaagaaat aatattgatg ggaaaaggga ttggccataa ttataaggct
   131821 gggtctgagt taaataaaaa agatatagaa aagatttttg ttcttcatga tgaaaatata
   131881 aaaaagagta ttatacaact ggcaacagaa atagatgcag aatattttgg tatagctcaa
   131941 atgataattg catatggaat agaaaaatat aacttaaaac ttatgaacca tatatatttg
   132001 gccttaactg accacattgc ctttgcagtg agacgcttta aagaaggtat aatgattgaa
   132061 aatcactatt tgtttgaaat caaggagttt aatccaaaag agtatgatat aggaaaatat
   132121 gcaattactg tttttaagga ggttcttggt ttagaactac cagaagaaga gattggtaat
   132181 atagcaggcc attttataaa tgcacaacaa gataatcctt atagtgatag aaataagaga
   132241 agtgctaaaa ttgtaaatgc tattttgcaa atagttcatt atcacttttc tattgtatat
   132301 aataaagagt cattttacta taggagattt gtaatgcatc taaaggcctt ttcacaaaga
   132361 tttctggcta acgaaccgtc aaaagaaaaa atagatttta tatatgagca agttcaaaaa
   132421 aattgtaagg aagagtatga atgtgtgaaa aaggtaggag cttatatgta taaggaatac
   132481 tccagagaat taccaagaca agaggagtta tatttgatga ttcatattca taagatttta
   132541 ggagaattat gcgaaaatag ttagaatatc ttaatatgct agtaatatta taaaaaatta
   132601 aaaattaatt acactttaaa tatgaataat tgcattactt aagggggttg tcttaaaatt
   132661 gattttttta attaaatttt aagttcaact cctttttaaa cctttatatc attacaactt
   132721 taatgtttat acgcctgtac ttcagatgtg tatctatttt ttacatttct caacatgaaa
   132781 atttatcatt ttttgtagtg tgttaattga aataaacctt tgagttaacc ctaaatttat
   132841 tctggaccta caggaatagt tccaaagata ctttaaaata ttttctggaa tgattgctta
   132901 tttcatatat attttattgt gatgttttga tttaataaat tcttcaactc cgtatatagt
   132961 aaatgtatta tcatgtttgt tttatttaag cacacttata atatgcttga ttttttcaaa
   133021 atgatgaaat atactaatgg gtgttggatg tataagaatc acattatact tgaaaaagta
   133081 agtgagaaat gaggtataat tcctcatatg ataaactact attgtattgt ggaacatatt
   133141 ctcagtgatg tcaagatatt acaatatgac taaattccta atgataaaaa agtctacgaa
   133201 tgagtgtaga aaggggaact aagatgaata aagttttaat tatagatgat gataaagatc
   133261 tttgtatttt gttaaaaaag agtatctcaa ttgaacatat tgaagcaaac tattgccatt
   133321 ctgggagaga tggattggtt gaactttcaa aacaagatta tcagttagta gttctagacg
   133381 tgatgatgcc aggtatggat ggttttgaaa ctatggaaca aatacgaaaa tatagcagta
   133441 ttcccatctt aatgctgaca tcgaaaaatg ataattacag caaagttcat ggattgcgag
   133501 ctggtgcgga tgactatcta accaaaccat ttgaaattgc agaatttact gctcgtgtac
   133561 tgtctttaat ccgacgttac acccgtttta atccaaagaa tgaggagtca cagcaacttt
   133621 ctttcaaagg tctgttgatt gaccttgacc agcatacagt gactaccaat ggcgaaacta
   133681 tgttgcttcc acccaaggaa tttggtgtgc ttctttactg tgcaaggcat cagggtaaga
   133741 ttttgacaaa acagcagatt tatgaagctg tgtggggtga gccatatgta tatgatgaca
   133801 gcaatatcat ggctattatc agtcgcctaa gaaaaaaaat tgaactagac ccatcatctc
   133861 ccatctattt gcaaacgata aaaggaatcg ggtatcaatt caacacggag gtatgaaaat
   133921 ggatgaacaa acgataattc tttttttgtt tttgctgtcg attggtctac ttttcctttc
   133981 catatttgct ttttccaagc ttggtcatat tcacaaacgt ctaaaagata tagaagaaat
   134041 acttgctgat gtacaaattg gaaacgaaaa tcgaaaaata ctaattaagc catgtgatgt
   134101 tatggctcca ttggtttatc agcttaatga gattgtctac gattatgaaa ataagttact
   134161 ttctctgaaa aagtcggata aagctagcaa acaacttatg acaagtttat ctcatgatgt
   134221 tcgtacacca ttaacgactc tgattggtta tctggatgct gtacacagtg gtatagttat
   134281 cggacaagaa cgggaggaat acattgaaat cgctcggcgt agagcctacg accttaagga
   134341 ttatatcgat gttctttttg actggtttcg attgaactct gatgaattta cgttgtcaat
   134401 agaatctgtg gaaattgcag agttgtcacg taatattctt aaagattgga ttcctatctt
   134461 ccatgaaaag aaattggatt ttgaaattga tattccagaa aatcgactaa tggtaaacct
   134521 tgattcagat ggatattctc gtgtagtcaa taatctagtt caaaacgttc ttgcccatag
   134581 caaggctcgc cgaatcaaaa ttaccatgag tgaggattct aagatggtat tacttcgtgt
   134641 tgaggataat ggtgttggga ttgccaaaga aaatttacag catatttttg agcgactgta
   134701 caagtgtgat aaaggacgtt caaaaaaagg aagtggtctt ggtttatcca ttgtcagtca
   134761 gatggtggag cgaatgggcg gtaagatttc tgtagaaagt gaaattggaa agtataccgt
   134821 atttatagtg agcttaccat taatataaaa attgtttttc ccccatgtga tatatataca
   134881 caggggggat tttttataag ctataaagtt gcaaggttaa tacaaggttg ttgcaaggtt
   134941 aatgtaagat tgaggtggta tgataaattt aataaacaaa ggaggatttt actatttatg
   135001 aataatttaa ttattgaaac aaaaaatctc actaaacaat atggtgctca aaagagcgtt
   135061 tctaatttga atattcatgt tcagaaaggt cgtatttatg gattgctggg aagaaatggt
   135121 tcgggtaaga cgacaactat gaaaatgtta ttgggtctaa caaaaccaac tactggagaa
   135181 attaaaatat ttggtcagga tattcataat aacgagaaaa agcttcttcc tagaattgga
   135241 tgtttgattg aatcaccagg tttttatcct aatctgacag gaacagaaaa tctcaaaatc
   135301 tttgcgaggc ttagaggaat accaaaaaaa aatgcagtag aatcagcact ggatgtagtc
   135361 ggtttgccaa acaatgacaa aaagttattt tctcaatact ctcttggtat gaaacagagg
   135421 ttggcaattg ctcttgccat tatgcatgac ccacaattgt tgattttgga cgagcctatc
   135481 aatggacttg atcctattgg tattgcagaa gtaagaaagt ttattcgtaa tctctgcaca
   135541 gaacgaggta aaactatttt gatttccagt cacattcttt ctgaaattgc tttgttggca
   135601 gatgacattg gcattattga ccgtggcatt ttgttggagg aagaaagcct tgcacaactg
   135661 gaagaaaaaa acagtaaata catacatttt gctgtatctg atgcagcaca agcagcaaga
   135721 cttctggaaa tccagcttaa cctgaaaaat ttcaaagtgg cagacaatca caatattatg
   135781 ctttatgata cagatgtctc tgttgcagaa ataaatcgtg ctttcattca aaacaatatt
   135841 gatgtatcag aatctcattt gtgcgaagat actcttgaag attacttcaa gaaagtaaca
   135901 gggggtgaag gaattgcttg atataatttc atgcgaattt tcaaaactca agcggttaaa
   135961 atttatactg atttctattt taggtgcttg tttatttcca attcccgcaa caattttgat
   136021 tgcaaaggac aacttgcctt ttgagcaatt gttcaaatta gttgtcaatt ttggatattt
   136081 tttgctatta ccaattgtat tgagtattgt tgctagccaa ctctttttca tagaaagaga
   136141 taacgatgta ttaaaaaatc tagcaacagt gccagtgcca aaaggaaaac tggctctggc
   136201 aaaattagct gtgttgctgt ttatatcatt gttctactcc gttgcagggt taggagctac
   136261 tatcatagga ggtttcattg ttggaatagt agagggggtt gctgtaaaat taggaatgag
   136321 tattgttttt ggaattatgt tttttgttac tgcacttcct gttgtggtac tcattgtata
   136381 tttcaatcgc agctatattt tttctattat actttctttt gtatatgcta ttttcaattt
   136441 tagtatatcc ttaaatatta tcaactttga accaaataac ccactgttaa gcgtattacc
   136501 tgctcctgtt ataatgcgtt ggtggatggc attttgggga gatcccactg gcgaatacac
   136561 ggcacttaga cagccatatt tactctcaac tcctgcttgt gtaggtattt tatgtttgat
   136621 aacaattatt gcagtcctgt tgatttgtat aatctacaag aagcaggaga attaggaggt
   136681 atctatgctt gatataatta ctacagaatt tcaaaaaata aaaagatata atattctatg
   136741 gattggtgtt gttgctgttc tgttttcagc actattggcg gtttttcaga ttgtaagttc
   136801 acacggcagt gaccctctaa cgtatgagag ctttgcaaat ggagttatat ggaataattt
   136861 cagtcttagt tttccatttg tgattacgct cattggagga tatcttatta accgtgaata
   136921 tacagaccaa accttaaaaa acatcctaac tattcctatt tcattacgca aattgctagt
   136981 gggaaaatta attgcggttg gaggaattac tgtattgtta agtattttca gcttcttatg
   137041 cacatttatt ttagggttac tattttgcaa tatcaatata tctgttatac tcgttgcaaa
   137101 atccttagtt cagattttgt ctgttaatct gtattgttat gttgctgttt tgccgattat
   137161 tgcttatttt ggtcgtaaac aaaattcctt tttgacaggc gtagggattg catttgtata
   137221 tggcttctgt ggtgtatttg ttgctggaag aaatctaaca gacttttatc caatcacagc
   137281 aggtcttggt ctagctggat acaacaatga tgatggtagt gtttatcagc cacttatagg
   137341 tgttatgact ttggttgtaa ttctaatcct gacagctatt ctacttacat ttacacctaa
   137401 ttacgataaa gttatgacca tatctaagaa aaaagggata aagcataaaa agtattctca
   137461 taaataacat aaatattgtt tctattattt aagttgtcag gcagtgaaaa gaaaaaatct
   137521 gtcgtacagt ggctatatgc tcatgtattt aagaagctac agttttgatt tttcataggt
   137581 gtggcttctt tttgtattta ttaaatcaac aactatcata atatttgcaa taggtatagt
   137641 aacaagagat aatactgtca tatgtgtttt atatattaca ttaagtatat tctaaaatat
   137701 atgttttaaa taatatattt gaaaataaga atacttgaat aaaaaaaata atattatata
   137761 tagttgacaa aaagtggaaa ttaatatact atataaatat agaaatagta atcattacta
   137821 atattaaaaa aggaggaatt aattatgaac ttaaaaggaa ctaaaacaga aaagaattta
   137881 atggcaggat ttgcaggaga gtcagaagca agaaataaat atacatacta cgcttcaaaa
   137941 gctagaaaag aaggttataa tcaaatagct gctatatttg aagaaactgc taacaatgaa
   138001 aaggaacatg ctaaattatg gtttaaactt ttacatgatg gtatgccttc aacagaggaa
   138061 aatttaaagg atgcagcagc aggcgaaaac tatgagtgga ctgacatgta tgcgaaattt
   138121 gctaaagaag ctagagaaga aggatttgac aagatagctt atttatttga ggctgttgga
   138181 aaaatagaga aagagcatga agaaagatac ttaaagcttt tagaaaactt aaatgaagga
   138241 aaaatattta aaagagatga agaagttgtt tggcaatgtc aaaactgtgg tcatgtgtat
   138301 gtaggtactg aagcaccaga aaaatgtcca gtatgtgacc atccaaaagc atatttcaat
   138361 ataaaagctg aaaattatta aaaattatca ttattaaaaa ggaatgttaa ctatgaaatt
   138421 ttctaaacaa cgagaactga ttttgaatga aatattaaat aatccggttc atcctactgc
   138481 ggattaccta tatgaaaact taaaaaaaga taatccaaat ctaagcttag gaactgtgta
   138541 tagaaattta tctcaactaa cggaacatgg ctttataaaa aaggttagta ttccagggta
   138601 tccagataga tttgatggta gaatagataa tcactatcat atcatatgtg aagtatgtgg
   138661 agaggtatac gatttagaat ctgaagttct taataattta aaagaattaa tatctgagga
   138721 gacagacata aaaataacat cttataacat aagttttaaa gggatttgta ataattgtaa
   138781 aagatgtagc caagtaggtt agcttttaaa ttctaaaaat aattaatgag gtgagtttat
   138841 gtgtagcgaa caaaaatttt ttatatgtga gacttgtgga aatcttgtag gaatgataca
   138901 aagtggtggt gtacctattt tctgttgtgg aaaacctatg aaggagcttg ttcctaatac
   138961 aacagatgca gcagttgaaa aacatgtacc tgtgattgaa gtggatggaa atagtgttac
   139021 tgttaaagta agtagtgcaa ttcatccaat gactaaagaa catcatatag catgggtgta
   139081 tcttatgact gaacaaggtg gtcaacgcaa atgtctagca gtagatggag aacctgtagt
   139141 taaatttgct ctgaatgatg atgataaagt gatttctgca tatgcttatt gtaatttaca
   139201 tggtttatgg aaggctgaac tgtaatattt aaataaattg agtcaaaaag gaggctataa
   139261 atgtattttc atacaaatag cctcctataa atttatataa attcgagttt taattttatt
   139321 taatgtcaat ataatataag gagaaaataa tatgtcaatt tacaaatgta gcgtttgcgg
   139381 atatatttat gatgaatcta agaatgataa aacatgggat gaattaagtg aagactggga
   139441 atgccctgta tgtacaaaag gtcgtagtta ttttggaaag ataagtactg tttactatga
   139501 agaagatgaa aatatagcag aagacatagt tgaagatgaa cctaaattaa atactgaaaa
   139561 agatggagat ttaaattacg taagtacata tttaagaaga gatgatgaag ttgagaaaca
   139621 tatggatata attcacgaaa tggctgttac aggaaaatct ataatagaac cgatgagaac
   139681 taaactacca gtaatttctt gggatgatat tttaattatg ggtgctcaat taaatccatt
   139741 acctttaaac gaacatgatg aagtaaatac aacaacaata atagggaaaa aagcaaagaa
   139801 gcctatgatt atagaaaatc cagtttatat ttcccacatg tcatttggag ctttatctaa
   139861 agaactaaaa atagctttag caaagggtgc cgctaaaagt aagacagcta tgtgtagtgg
   139921 agaaggtggt atattaccag aagaaaaaga agcttcatat aagtatattt ttgaatatgt
   139981 accaaataaa tatagtgtaa ctgaagaaaa tcttaaaaat tctgatgcta tagaaataaa
   140041 aattggtcaa ggaacaaaac ctggtatggg aggtcatctt cctggtgaaa aagtaactga
   140101 agaaatagca aaggtaagaa ataagcctgt aggtaaagat gtaataagtc catcttgttt
   140161 tgaggaaata caatccaaag aagatttaaa gaaacttgta gatgaactta gagaagtttc
   140221 agaaggtcgt ccaataggtg ttaaaatttc agctggtcat attgaaaaag atatggaatt
   140281 tatagcttat gctaaacctg attttgtgac tattgatggt cgtggtggag ctactggagc
   140341 aagcccaaag ttgcttaaag atgcaacttc aatcccaaca atatttgcac tttatcgtgc
   140401 tagaaaatac atagatacac atggattaga tatagatttg gttataacag gtgggcttcg
   140461 tatatctact gattttgcca aggcaattgc tatgggtgct gatgcagttg ctattgcaag
   140521 ttctgctctt atggcagcag catgtcaaca atatcgtata tgtggttctg gtaagtgccc
   140581 tgtaggagta gctactcagg atgaggaatt gagaaaaaga ttacatatag aaaatagtgc
   140641 taatagagtg gcaaactttt taaatgtaag tttagaagaa cttaagactt ttgctagaat
   140701 ttctggtcat aaagatatac atgatttaag tgttgatgat ttatatactg ttaactctga
   140761 aatatcaaat tacacaaaca tacaacatgt ataagttgaa gtttgagact attagattgt
   140821 agatagttat aaaagtaaat gataaatata ttttataaaa aggagtgtct taaaatgaac
   140881 tttttagttt ataagtcact cttttttgta tgaagccaaa tatatttatc attttaacaa
   140941 tgaaaaagaa tcttatatct ttactttgag atagattcct tctatttatg aaaattaaag
   141001 atattaaatt gtaaaacatt ctgtgatgtc gtactattaa actaaagatg ctgtacttta
   141061 aagtaaataa aaatttaagg agtgattatt atggaaaaat tgaagattca agttctagtt
   141121 gacaataata catatattga taggtacttt gttggagaac cagcagtaag ctattacatt
   141181 gagattgatg gaaataggat tttgtttgat taaaaaatag ctacgaacac ttgtga
//
LOCUS       DBGJFK010000002       108137 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.002, whole genome shotgun sequence.
ACCESSION   DBGJFK010000002 DBGJFK010000000
VERSION     DBGJFK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 108137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 108137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..108137
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.002"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(196..609)
                     /locus_tag="ACOIAP_000127"
     CDS             complement(196..609)
                     /locus_tag="ACOIAP_000127"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HGZ2637053.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRV"
     gene            complement(650..1780)
                     /gene="rodA"
                     /locus_tag="ACOIAP_000128"
     CDS             complement(650..1780)
                     /gene="rodA"
                     /locus_tag="ACOIAP_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HGZ2637054.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNFLGRYYKALYIISLVLLAIVLLPGIGS
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVIVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQENFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(1864..2148)
                     /gene="minE"
                     /locus_tag="ACOIAP_000129"
     CDS             complement(1864..2148)
                     /gene="minE"
                     /locus_tag="ACOIAP_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HGZ2637055.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(2166..2963)
                     /gene="minD"
                     /locus_tag="ACOIAP_000130"
     CDS             complement(2166..2963)
                     /gene="minD"
                     /locus_tag="ACOIAP_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HGZ2637056.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(2987..3670)
                     /gene="minC"
                     /locus_tag="ACOIAP_000131"
     CDS             complement(2987..3670)
                     /gene="minC"
                     /locus_tag="ACOIAP_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA];
                     GO_process: GO:0051302 - regulation of cell division
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HGZ2637057.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKVEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(3768..6746)
                     /locus_tag="ACOIAP_000132"
     CDS             complement(3768..6746)
                     /locus_tag="ACOIAP_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGZ2637058.1"
                     /translation="MEENKQVDRLKIIKIVMSVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKNLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLN
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEDV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(6758..7246)
                     /gene="mreD"
                     /locus_tag="ACOIAP_000133"
     CDS             complement(6758..7246)
                     /gene="mreD"
                     /locus_tag="ACOIAP_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGZ2637059.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGANALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFIKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(7261..8154)
                     /gene="mreC"
                     /locus_tag="ACOIAP_000134"
     CDS             complement(7261..8154)
                     /gene="mreC"
                     /locus_tag="ACOIAP_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGZ2637060.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDIANFKDNSKKVKKLEEENEKLKKDMIS
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISTSVVSKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(8164..9225)
                     /locus_tag="ACOIAP_000135"
     CDS             complement(8164..9225)
                     /locus_tag="ACOIAP_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HGZ2637061.1"
                     /translation="MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVRE
                     PSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQK
                     AADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVE
                     EPEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERT
                     AENVKINIGSTFKDDEEVNMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIK
                     STLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTG
                     KSVEDQEIFEKVLMMNTKN"
     gene            complement(9295..9954)
                     /gene="radC"
                     /locus_tag="ACOIAP_000136"
     CDS             complement(9295..9954)
                     /gene="radC"
                     /locus_tag="ACOIAP_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGZ2637062.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGDKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKATQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSVGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(9999..10583)
                     /locus_tag="ACOIAP_000137"
     CDS             complement(9999..10583)
                     /locus_tag="ACOIAP_000137"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HGZ2637063.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLSDLLKKYFSINLFYGV"
     gene            complement(10803..11774)
                     /locus_tag="ACOIAP_000138"
     CDS             complement(10803..11774)
                     /locus_tag="ACOIAP_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HGZ2637064.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     VAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(11790..12365)
                     /gene="rsxA"
                     /locus_tag="ACOIAP_000139"
     CDS             complement(11790..12365)
                     /gene="rsxA"
                     /locus_tag="ACOIAP_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HGZ2637065.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(12380..12973)
                     /locus_tag="ACOIAP_000140"
     CDS             complement(12380..12973)
                     /locus_tag="ACOIAP_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit E"
                     /protein_id="HGZ2637066.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(12986..13555)
                     /locus_tag="ACOIAP_000141"
     CDS             complement(12986..13555)
                     /locus_tag="ACOIAP_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HGZ2637067.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMDKSTYKDLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(13555..14532)
                     /locus_tag="ACOIAP_000142"
     CDS             complement(13555..14532)
                     /locus_tag="ACOIAP_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HGZ2637068.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFAKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(14555..15892)
                     /gene="rsxC"
                     /locus_tag="ACOIAP_000143"
     CDS             complement(14555..15892)
                     /gene="rsxC"
                     /locus_tag="ACOIAP_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HGZ2637069.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKTIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTVTGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDVQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(16108..17052)
                     /locus_tag="ACOIAP_000144"
     CDS             complement(16108..17052)
                     /locus_tag="ACOIAP_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637070.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKNGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIDSISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(17163..18437)
                     /locus_tag="ACOIAP_000145"
     CDS             complement(17163..18437)
                     /locus_tag="ACOIAP_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HGZ2637071.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSNPNNSTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGEVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGANNSSNSNSTNNSDKKPSSEESIEGKNGKVTSTVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKNNGWYKVKLSNGTTGWVSGSYISETNEGTKENSNSSSN
                     QNSQSNNNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(18569..18940)
                     /locus_tag="ACOIAP_000146"
     CDS             complement(18569..18940)
                     /locus_tag="ACOIAP_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGZ2637072.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(19167..19766)
                     /locus_tag="ACOIAP_000147"
     CDS             complement(19167..19766)
                     /locus_tag="ACOIAP_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637073.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(19967..20179)
                     /locus_tag="ACOIAP_000148"
     CDS             complement(19967..20179)
                     /locus_tag="ACOIAP_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HGZ2637074.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDSVSIEKLKEVIAELGFELKGIE"
     gene            complement(20252..21967)
                     /locus_tag="ACOIAP_000149"
     CDS             complement(20252..21967)
                     /locus_tag="ACOIAP_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2637075.1"
                     /translation="MKRIKVLTVVLAITLMVVGCSNSKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKDVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQSHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKALECLAKVEYANVNPVNQNDNKIKNQKKPAKKNLKKLTPEEEAKAKKAEE
                     DSIKKEAEEKQNREKEEVKKKLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKDYDLALVGWKLSSIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSSSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(21967..22521)
                     /locus_tag="ACOIAP_000150"
     CDS             complement(21967..22521)
                     /locus_tag="ACOIAP_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HGZ2637076.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEQYNKIYGKKGKN"
     gene            complement(22514..23116)
                     /gene="coaE"
                     /locus_tag="ACOIAP_000151"
     CDS             complement(22514..23116)
                     /gene="coaE"
                     /locus_tag="ACOIAP_000151"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGZ2637077.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNISIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKKLNNLTHPRIREKIISEIEELR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALNRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(23125..25773)
                     /gene="polA"
                     /locus_tag="ACOIAP_000152"
     CDS             complement(23125..25773)
                     /gene="polA"
                     /locus_tag="ACOIAP_000152"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGZ2637078.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAEDDGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLLENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLESMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSNDTEQVEEKIEILKLKDIEKFIDEVNEKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITISEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNIDVHLDVDLNVGSSWYETK"
     gene            26092..26174
                     /locus_tag="ACOIAP_000153"
     tRNA            26092..26174
                     /locus_tag="ACOIAP_000153"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26126..26128,aa:Leu,seq:caa)
     gene            26865..28274
                     /locus_tag="ACOIAP_000154"
     CDS             26865..28274
                     /locus_tag="ACOIAP_000154"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HGZ2637079.1"
                     /translation="MIFSSLIFLFLFFPVTLICYYLANPKYKNVMLLLASIAFYTWGE
                     PKYIFLMILSIIVNYIFGIKVSGSKNKKMWVVLSVIYNISILAVFKYSNFFIDNINFL
                     FNTDITIPEVKLPLGISFFTFQIMSYVIDVYRNDAKVQRKLANLALYISLFPQLVAGP
                     IVRYQTVADSIEYREHNWDKFTQGVNRFVVGLGKKVILANQLGVIADGVFNKSAGDLS
                     RFEVWLGIVCYTLQIFYDFSGYSDMAIGLGKMFGFEFLENFNYPYISQTVSEFWRRWH
                     ISLGTWFKDYVYFPLGGNRVSKAKLYRNLFVVWFLTGMWHGTSWTFIILGLYYGILIS
                     VEKAFLEKFLYKMPRIVRHIYLLLIVMIGWVFFRVDDLPAAIKFIGIMFGAGNYPVIS
                     NAFNVFIIEYWYVIVGAILLSTPIVKVLKSLLIKKNKNTLNSTLYQVTNMVFIVSCMF
                     IVIIMLSSSTYNPFLYFRF"
     gene            28290..29483
                     /locus_tag="ACOIAP_000155"
     CDS             28290..29483
                     /locus_tag="ACOIAP_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHHW family protein"
                     /protein_id="HGZ2637080.1"
                     /translation="MSKKKPRIVAISFLIIVFGFFILNFTLPKKKLSITENRNLAKFP
                     TVENLKKGDFIAKFEEYFNDHFAFRDRMISINTKAQASLNKTKVGNYYLGKDNWILGM
                     FPEILDQKQLSRYEKSINYLSNLSKDMGKNVYFTMMPHKTNMLKHLYPKYVDNMDNID
                     INLKNFKNRLNPDLIKYIDMDEYFLSNYSDKERENLYFKTDHHWTGYGAFEGFKMMAS
                     NMDLGLSKQDLDKHFSSYKKSIITDKKFIGSYNQNIDMLIKENEYVVYMTKDNQDYSF
                     DINGEEKEEKEVYATERDNKEWDYGGAYIRGAKTNILTIKNPKALVNKKILIFRDSYQ
                     APTTLLFADMFKEVEIADPRNINSIYKTYKEIIEESNADIVMFMYNSSGFDSMIDSMI
                     DKGIK"
     gene            29660..29980
                     /locus_tag="ACOIAP_000156"
     CDS             29660..29980
                     /locus_tag="ACOIAP_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637081.1"
                     /translation="MLKNLYPSGIKGKNNIDINKENLEKQLKDINFLDIDDYFYKSFT
                     EKERENFFLKTDHHGNSLGAFEEYKFILDKLDLSLSKSEIDSHLKRYSTRYVNDCECS
                     FIYV"
     gene            complement(30500..30943)
                     /locus_tag="ACOIAP_000157"
     CDS             complement(30500..30943)
                     /locus_tag="ACOIAP_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637082.1"
                     /translation="MKKNMLYLGIVYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERALDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(30946..31143)
                     /locus_tag="ACOIAP_000158"
     CDS             complement(30946..31143)
                     /locus_tag="ACOIAP_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2637083.1"
                     /translation="MKNRLEEIRKERGIKQEELASVLQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDRSIEEIFIYEEE"
     gene            complement(31335..32201)
                     /locus_tag="ACOIAP_000159"
     CDS             complement(31335..32201)
                     /locus_tag="ACOIAP_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGZ2637084.1"
                     /translation="MEWINKLNQAITYIEENLESGIDYAEAAKIACCSTFHFQRMFSY
                     IAEVPVSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNVEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPILEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYSNLPDIELYPNGDINSPDY
                     TTEVWIPIQKPS"
     gene            complement(32426..33295)
                     /locus_tag="ACOIAP_000160"
     CDS             complement(32426..33295)
                     /locus_tag="ACOIAP_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2637085.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDIRIMNRSEVFNNLEKVAGYKGNMIDSPSYIIILSDVKDNYIENSGYIGENIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGIDSDKEVTGIIAIGYGENVNNAKVLNATKTGQNYSK
                     SDMQVVTDKGSSRLGVEDVVYMNEWGNVASIEVLEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVILAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFELKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(33801..34022)
                     /locus_tag="ACOIAP_000161"
     CDS             complement(33801..34022)
                     /locus_tag="ACOIAP_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637086.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEEHEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(34523..35503)
                     /locus_tag="ACOIAP_000162"
     CDS             complement(34523..35503)
                     /locus_tag="ACOIAP_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637087.1"
                     /translation="MGDTSRFYESVRNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDILSWKQIVVLAECDGKNTTDDIINILSNRYRNIPNMREKVMEFFMFYENV
                     YLTFEDNIQTVSSVFEITGNKSYITPLYFTLEIDADNNTNNYFSEITSLLKCMYEKGC
                     RFIEVIGEDILKNKGMRDVFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSRNDDTRIKLKEDIKITSLIKRGHTVVRRDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSNGNVKSYSFQKDKRVYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(35667..36539)
                     /locus_tag="ACOIAP_000163"
     CDS             complement(35667..36539)
                     /locus_tag="ACOIAP_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGZ2637088.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPVEFDN
                     FKIVQVSDLHNKVFDKNNKVLMDKIKSLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINLENESVRIYKGNSHLNLYG
                     LIVPLECYPYFFANNKKLELSDNFVESNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRMPFVGGVLSPNREFFPKYDWGRYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKSKK"
     gene            complement(36703..37254)
                     /locus_tag="ACOIAP_000164"
     CDS             complement(36703..37254)
                     /locus_tag="ACOIAP_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637089.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQQGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(37274..38176)
                     /locus_tag="ACOIAP_000165"
     CDS             complement(37274..38176)
                     /locus_tag="ACOIAP_000165"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGZ2637090.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCISCNRCVDVCPQNISSLFDRTQINNKCDLCGECIKACLKDAICIMT
                     EEMSVEEIVKEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYNKGINIAIET
                     CGYFDWNKVNDVFDKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPEGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(38191..40563)
                     /locus_tag="ACOIAP_000166"
     CDS             complement(38191..40563)
                     /locus_tag="ACOIAP_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HGZ2637091.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDERTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKVLVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISISENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSEQETDKKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDNAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLNQLAYLVKNSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMVKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(40784..41473)
                     /locus_tag="ACOIAP_000167"
     CDS             complement(40784..41473)
                     /locus_tag="ACOIAP_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637092.1"
                     /translation="MKVKRNINKVAIVVALNLSLALMVGCKSPVSDKNLSSSKQISKD
                     SLKESVEDKKDESIELFNNYSQKMNDVKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINSVEKPPEENIRSLFYSVSEDDKEGKVTIDILCAKEYPEDEKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKIKQSTKVLKL
                     SLLYKFDISNR"
     gene            complement(41714..43093)
                     /locus_tag="ACOIAP_000168"
     CDS             complement(41714..43093)
                     /locus_tag="ACOIAP_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGZ2637093.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIVQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKIGYIKYSVFFYLFSVY
                     YECLDAVIYRILFFAITGNVISSKESLLIPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLANTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDKLRNNSKEIDEYVNSLKDEIKAFKYIYNTGNMILDIIINEKSEICLKKGIKFICS
                     INFSKVNFVKPIDVSSIFSNVLDNAIEACDKILDENINKYIRIKGTITKSFFVLKCEN
                     SKLNKITFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELSFENSMDKFILNIYIPL
                     DQDTDSWSD"
     gene            complement(43087..43800)
                     /gene="rgbR"
                     /locus_tag="ACOIAP_000169"
     CDS             complement(43087..43800)
                     /gene="rgbR"
                     /locus_tag="ACOIAP_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HGZ2637094.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILEDINIEYEIQKYLSGEDLL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFITSLIDYVQEGYEVRAYRY
                     LLKPIELEDLKKHVLTCIKDIEINKKSHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLSKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTVILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(44047..44598)
                     /locus_tag="ACOIAP_000170"
     CDS             complement(44047..44598)
                     /locus_tag="ACOIAP_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGZ2637095.1"
                     /translation="MEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYRINKFGGIFYF
                     HKESPRKIKYTVDYYYDAENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYKDIP
                     PKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGCGASVTAIVLQII
                     LLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(44703..45506)
                     /gene="zupT"
                     /locus_tag="ACOIAP_000171"
     CDS             complement(44703..45506)
                     /gene="zupT"
                     /locus_tag="ACOIAP_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HGZ2637096.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGGWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGVFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(45657..46820)
                     /locus_tag="ACOIAP_000172"
     CDS             complement(45657..46820)
                     /locus_tag="ACOIAP_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2637097.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     MGIPYVSAGGTGVIATIKGANSGKTVALRGDMDALQVVECTEVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKKIPGILERIAKS
                     TAGAYRAEAELEYGYLTPAVINDKECSKIATEAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(46880..48067)
                     /locus_tag="ACOIAP_000173"
     CDS             complement(46880..48067)
                     /locus_tag="ACOIAP_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637098.1"
                     /translation="MEAITAFCLVLISLTIGDVVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTAEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVMCLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIAGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(48430..50130)
                     /locus_tag="ACOIAP_000174"
     CDS             complement(48430..50130)
                     /locus_tag="ACOIAP_000174"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637099.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIRDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPEGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(50370..50645)
                     /locus_tag="ACOIAP_000175"
     CDS             complement(50370..50645)
                     /locus_tag="ACOIAP_000175"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2637100.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEIEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(50764..51297)
                     /gene="mobB"
                     /locus_tag="ACOIAP_000176"
     CDS             complement(50764..51297)
                     /gene="mobB"
                     /locus_tag="ACOIAP_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HGZ2637101.1"
                     /translation="MYNILSVVSYSGVGKTTLIEGIIKELNKKGYRVGVIKHTCHDFD
                     MDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKDKSPLYKMIQLYEDMDLIIIEGYK
                     NYRFKRLEVTRKDKYEDIFSNKSDLVGIVSDIKYNLNIKQFDLNDYKNISKYIESCIK
                     NDILSISNVEIKNILKE"
     gene            complement(51320..52501)
                     /locus_tag="ACOIAP_000177"
     CDS             complement(51320..52501)
                     /locus_tag="ACOIAP_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HGZ2637102.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKRVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGEVFNRVLNKGEAVKIMTGGKIPRGANC
                     VIKKEDVTVIGDMITLNVKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVRDMLQNADFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVATLGEKLLFGLSGNPHAAIIVFDNVVVPVIEYLTYKKGIHYIKAIFKGEFNKLSN
                     KDRFVNGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDIVI
                     R"
     gene            complement(52713..53447)
                     /locus_tag="ACOIAP_000178"
     CDS             complement(52713..53447)
                     /locus_tag="ACOIAP_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637103.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINGNKVVNVETNSFSSQGIAVVDAESSIVIEKSDHEKSAVSLENFR
                     RIDLGEYVGVEESRITEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            53810..54715
                     /locus_tag="ACOIAP_000179"
     CDS             53810..54715
                     /locus_tag="ACOIAP_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism-associated LysR family
                     transcriptional regulator"
                     /protein_id="HGZ2637104.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVNK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(54875..55717)
                     /locus_tag="ACOIAP_000180"
     CDS             complement(54875..55717)
                     /locus_tag="ACOIAP_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGZ2637105.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(55701..56459)
                     /locus_tag="ACOIAP_000181"
     CDS             complement(55701..56459)
                     /locus_tag="ACOIAP_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGZ2637106.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHLADRYAEEGNIEGVERIQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(56476..56946)
                     /locus_tag="ACOIAP_000182"
     CDS             complement(56476..56946)
                     /locus_tag="ACOIAP_000182"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2637107.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDELLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDINMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(56946..57689)
                     /locus_tag="ACOIAP_000183"
     CDS             complement(56946..57689)
                     /locus_tag="ACOIAP_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA/SgcQ family protein"
                     /protein_id="HGZ2637108.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEIAIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENNIEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLELGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(57693..58106)
                     /locus_tag="ACOIAP_000184"
     CDS             complement(57693..58106)
                     /locus_tag="ACOIAP_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2637109.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVKLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(58131..58883)
                     /locus_tag="ACOIAP_000185"
     CDS             complement(58131..58883)
                     /locus_tag="ACOIAP_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2637110.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(59123..60517)
                     /locus_tag="ACOIAP_000186"
     CDS             complement(59123..60517)
                     /locus_tag="ACOIAP_000186"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGZ2637111.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENGYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAVPLALHGIVILNDGTKVEIS
                     IGEEDNDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLDDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(60537..60746)
                     /locus_tag="ACOIAP_000187"
     CDS             complement(60537..60746)
                     /locus_tag="ACOIAP_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HGZ2637112.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(60774..62219)
                     /locus_tag="ACOIAP_000188"
     CDS             complement(60774..62219)
                     /locus_tag="ACOIAP_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGZ2637113.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESMDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINEKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            62329..63123
                     /locus_tag="ACOIAP_000189"
     CDS             62329..63123
                     /locus_tag="ACOIAP_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HGZ2637114.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQNKYKDKISIKKGIEFGVQTQLIDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLRQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            63173..64495
                     /locus_tag="ACOIAP_000190"
     CDS             63173..64495
                     /locus_tag="ACOIAP_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGZ2637115.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALTISIV
                     ASFNSSFLSIKFLKDAKLNLFILAVCPAIVIITISNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGVISG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKAIH"
     gene            complement(64595..65827)
                     /gene="cdeC"
                     /locus_tag="ACOIAP_000191"
     CDS             complement(64595..65827)
                     /gene="cdeC"
                     /locus_tag="ACOIAP_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HGZ2637116.1"
                     /translation="MQDYKKNKRRMTNQPMPTMNEEEVYTEEINSEDMRGFKKSHHHN
                     ECNTDNKCDCHDDCKPCNPCKPNPCNPCKPNPCNPCKPNPCDDNCGCHDHCKCDCEPC
                     EMDSDECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGE
                     PLTFETEVVEVFGSVPSAGKASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGR
                     NCETTFEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALA
                     FPAVRAGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILK
                     LECNECCEPFYELIIPNDIDLVLCLQNTVSTLISEQIVVLASPNPIQPRLVDTFSKVC
                     DFSQCGPNHESGKPSCHR"
     gene            complement(66012..66192)
                     /gene="ssrS"
                     /locus_tag="ACOIAP_000192"
     ncRNA           complement(66012..66192)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACOIAP_000192"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(66307..67218)
                     /locus_tag="ACOIAP_000193"
     CDS             complement(66307..67218)
                     /locus_tag="ACOIAP_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637117.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHSNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSKDERKILIKIESVL
                     DLVRGIKKLNNIDMVDIEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNEDEDNN
                     EGLNNEDEELDYEDKELDYDDEELTDEDEMEDNEDELVEDNKTDYENIENDEDIVYDE
                     ELYNINEQESEYNYNAKNTKTRTKKKR"
     gene            67430..67828
                     /locus_tag="ACOIAP_000194"
     CDS             67430..67828
                     /locus_tag="ACOIAP_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637118.1"
                     /translation="MKKLDAESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDTIMEKISDAETQRDTKPAKTKKTKPTKGKS
                     NSPAPKNTPTGQQKKSKGLFKKTKKSNPHE"
     gene            complement(67950..68972)
                     /gene="ccpA"
                     /locus_tag="ACOIAP_000195"
     CDS             complement(67950..68972)
                     /gene="ccpA"
                     /locus_tag="ACOIAP_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HGZ2637119.1"
                     /translation="MKMKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEV
                     IKETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANT
                     YSDKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYT
                     VSTSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKS
                     LIKYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVS
                     GFNDVKIAKMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRES
                     VIERKK"
     gene            complement(69219..69419)
                     /locus_tag="ACOIAP_000196"
     CDS             complement(69219..69419)
                     /locus_tag="ACOIAP_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637120.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSSGGFFDGEVGCGC"
     gene            complement(69453..69632)
                     /locus_tag="ACOIAP_000197"
     CDS             complement(69453..69632)
                     /locus_tag="ACOIAP_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637121.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(69814..70020)
                     /locus_tag="ACOIAP_000198"
     CDS             complement(69814..70020)
                     /locus_tag="ACOIAP_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637122.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(70068..70493)
                     /locus_tag="ACOIAP_000199"
     CDS             complement(70068..70493)
                     /locus_tag="ACOIAP_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637123.1"
                     /translation="MKYVGLLLTSIGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            70665..70892
                     /gene="acpP"
                     /locus_tag="ACOIAP_000200"
     CDS             70665..70892
                     /gene="acpP"
                     /locus_tag="ACOIAP_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGZ2637124.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(71033..72037)
                     /locus_tag="ACOIAP_000201"
     CDS             complement(71033..72037)
                     /locus_tag="ACOIAP_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGZ2637125.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVPNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(72051..72953)
                     /locus_tag="ACOIAP_000202"
     CDS             complement(72051..72953)
                     /locus_tag="ACOIAP_000202"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGZ2637126.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKINEEKANFEPQDLNLQIIYDDFDIIMVNKLPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGCVDEELINRQALHAYRLEFEQP
                     RTKEKLKFKADIPEDIKELISKLR"
     gene            complement(73150..74325)
                     /locus_tag="ACOIAP_000203"
     CDS             complement(73150..74325)
                     /locus_tag="ACOIAP_000203"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HGZ2637127.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTSLIVKR"
     gene            complement(74413..75258)
                     /locus_tag="ACOIAP_000204"
     CDS             complement(74413..75258)
                     /locus_tag="ACOIAP_000204"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HGZ2637128.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(75356..76153)
                     /locus_tag="ACOIAP_000205"
     CDS             complement(75356..76153)
                     /locus_tag="ACOIAP_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HGZ2637129.1"
                     /translation="MSTSDVKVYENVAVEVNGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPEILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(76172..77182)
                     /locus_tag="ACOIAP_000206"
     CDS             complement(76172..77182)
                     /locus_tag="ACOIAP_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HGZ2637130.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVEVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(77201..77983)
                     /locus_tag="ACOIAP_000207"
     CDS             complement(77201..77983)
                     /locus_tag="ACOIAP_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HGZ2637131.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(78042..79178)
                     /locus_tag="ACOIAP_000208"
     CDS             complement(78042..79178)
                     /locus_tag="ACOIAP_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009272751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HGZ2637132.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(79886..80353)
                     /locus_tag="ACOIAP_000209"
     CDS             complement(79886..80353)
                     /locus_tag="ACOIAP_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HGZ2637133.1"
                     /translation="MSISNVREYFKQFGKDDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLIPEEVLEFTGHAIGGVCPFG
                     LKNSLKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(80432..80974)
                     /locus_tag="ACOIAP_000210"
     CDS             complement(80432..80974)
                     /locus_tag="ACOIAP_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637134.1"
                     /translation="MKKFIKVSFFIFGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDIGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGINKCSSYVNIDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYVVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(81026..81712)
                     /locus_tag="ACOIAP_000211"
     CDS             complement(81026..81712)
                     /locus_tag="ACOIAP_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HGZ2637135.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLMSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGLIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDMANAKYINLYSMTFLTIIIFIISMYFSI
                     RISKKNKFNY"
     gene            complement(81712..82572)
                     /locus_tag="ACOIAP_000212"
     CDS             complement(81712..82572)
                     /locus_tag="ACOIAP_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637136.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     EFDRERFDEYLNKFDIEENMHIKNLSKGQSEKLMLSSALSHNAKLLILDEPTTGIDPI
                     VRSEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            82706..83506
                     /locus_tag="ACOIAP_000213"
     CDS             82706..83506
                     /locus_tag="ACOIAP_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HGZ2637137.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            83531..84100
                     /gene="yfcE"
                     /locus_tag="ACOIAP_000214"
     CDS             83531..84100
                     /gene="yfcE"
                     /locus_tag="ACOIAP_000214"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HGZ2637138.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YTESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(84358..85410)
                     /locus_tag="ACOIAP_000215"
     CDS             complement(84358..85410)
                     /locus_tag="ACOIAP_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HGZ2637139.1"
                     /translation="MKIKSRKIIAFVLSLGIMMPSCVYADTISKNQNTEVDMNNYLQG
                     RKSPKEETLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKEFLEDMGVLVSRIGGADREE
                     TSLLLTKQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTETYIVGGEYSISKKLEGQLVNAERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(85617..86843)
                     /gene="pepT"
                     /locus_tag="ACOIAP_000216"
     CDS             complement(85617..86843)
                     /gene="pepT"
                     /locus_tag="ACOIAP_000216"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGZ2637140.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEELNVITYVKDSPELVEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFNVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIATEISEMFPADERPETTEGYEGFWHLNSIDGNVENVS
                     MSYIIRDHCREKFEYRKSIMVENIEQINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELNIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            complement(86936..87988)
                     /gene="ytvI"
                     /locus_tag="ACOIAP_000217"
     CDS             complement(86936..87988)
                     /gene="ytvI"
                     /locus_tag="ACOIAP_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HGZ2637141.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGGI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSVKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDIEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            complement(88136..89389)
                     /locus_tag="ACOIAP_000218"
     CDS             complement(88136..89389)
                     /locus_tag="ACOIAP_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HGZ2637142.1"
                     /translation="MLESPDNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            complement(89520..93047)
                     /locus_tag="ACOIAP_000219"
     CDS             complement(89520..93047)
                     /locus_tag="ACOIAP_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2637143.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNLQLQSLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQNSYEESKTVYEEQLKLEKNELRKNELDLKNGEIKEKI
                     ALVENDSNAKKVDPYIGSVQNLEKKIDEDSFTVSNLEKKLVILNQELEVIKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDKELKELKESGINLNKTKVELEKVKQMS
                     ESRKDAVTKSIKEVEGKINKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKINKLEEI
                     LKETEDINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KADNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEQLK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKLSGYLSIEKMKTKELEDVKGKLGDIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYIGLKTITKVSNLLSKVKEIRENEKELELLSIGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYLEKKLSRDNKYKEVINITKGDLAKNLLHSVEEDICKILEQEESSKK
                     KLEQQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     ADEVKKLIEEILEHEEEQKLLAFKIKSSKEKLNGRSVKKESFEQLKDEIYNLKVEIGN
                     ISKNIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            complement(93034..94245)
                     /locus_tag="ACOIAP_000220"
     CDS             complement(93034..94245)
                     /locus_tag="ACOIAP_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HGZ2637144.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITCATQGCTKLNINGENVVVATLPYPSEKRLNEVFSSE
                     DDFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDKEIWSYFEINTEEVISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            complement(94289..98116)
                     /gene="addA"
                     /locus_tag="ACOIAP_000221"
     CDS             complement(94289..98116)
                     /gene="addA"
                     /locus_tag="ACOIAP_000221"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGZ2637145.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRISLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSAEYKKIVDISQACNKSWDETYKK
                     MSSMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISNIVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNEFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFEMDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRTNNKESEIEEEEK
                     LDNIQLEARMVGKIIKDLMKVNEEGKLQKVYDKGIGGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYNEFKDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGVENSDTISQYEILKGKNFLDWIMPCVLKHRDLSN
                     LLDEVGLDAVFSVEHNSKWYGKLWDKNDILVEKKNNEEKESIEKILEKIDVDSPDSDY
                     YNEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEERDKISGAERGTIVHLVMEVLDLKNVSNVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFESNIGKRMLNAELINREKSIYAQVNMKDIYIYEKLINNDDKKLYDEESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            complement(98116..101583)
                     /gene="addB"
                     /locus_tag="ACOIAP_000222"
     CDS             complement(98116..101583)
                     /gene="addB"
                     /locus_tag="ACOIAP_000222"
                     /EC_number="3.1.-.-"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HGZ2637146.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRMLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQAGFVSSITEMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDVNYTGYSKADMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSKQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     EKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINVLENYVLANGIKGKKWFDEKWDYRITQSLSGE
                     ESEFELELKDKINEIKNRVLEPIVTLQEKLKGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSQTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDEDILKKITVKSPTFNELINVIKNYDSDGYNKEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHRIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKARKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLSWRGIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKIVLENGQEVSLIGQIDRVDEFEEGENKYIRIVDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDKDININPAAILYCRINNPIAKFNEDKDDVEIQEAILKELRMKG
                     LVVKDSHIVKKMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVKH
                     AIKDLCEDMLSGEICIAPYKHKDGTSCDFCDYSAICQFDSTMKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            complement(101573..102403)
                     /locus_tag="ACOIAP_000223"
     CDS             complement(101573..102403)
                     /locus_tag="ACOIAP_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HGZ2637147.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDNKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMSLNGDTIQAKYDLVVIGNNNIDIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYNEEKHETNRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            complement(102512..104731)
                     /locus_tag="ACOIAP_000224"
     CDS             complement(102512..104731)
                     /locus_tag="ACOIAP_000224"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HGZ2637148.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILVLTYMNSAVNNFKGRIRKILEEHKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKNIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGQKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENRNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVEYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINIKWYDSWKFEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLVFEELGPNSLSKRRVINNIASIIDFILHCDD
                     IEKLIVVLDKVFIDTDNEEELKYFLEKLKNYSTEEIIYDFEFSKLDNDLIEFNEESDI
                     YLNFKRGINIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLASENI
                     NMDLEDVYNLLFDVKNKVFNHIIDVVYEINGYEPEPGSITICNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLGRLNRHIIKKRSN"
     gene            complement(104724..106637)
                     /locus_tag="ACOIAP_000225"
     CDS             complement(104724..106637)
                     /locus_tag="ACOIAP_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637149.1"
                     /translation="MEYLIDKSSLKECGNEPLDKYREILDKTKNNSRSILLLVPNNNT
                     KIQYERSLRLNYSEELKITTYISFVKKELLKYWPLIIENCDEINKKAVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIAKSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNSLSVYLYNQYLLNDDFYVKSLFKEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDMDYINEKIISKIK
                     SKEENIKRKEIGIEDLYLLPATIKLNQSSQLYNEMLDLISEKIISLIEEGVSLRDIAI
                     ISPINNSILEYQIRDSLIEKNIDVFNIKKDKKAVDYPYGNALVVATCMFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNMDEHSQYRDILQYIEEKKKSDLKIHE
                     FLIQFYIDKMLSLKDGKKNVGLCKKIIAESESFSESLSLLGMKKEEIFIEALKTAIND
                     YYSVVDIEELKSKDKIVITTPYSYIASNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAYKSEYAINGYIQESILYSI
                     LLKISHKGDENYD"
     gene            complement(106869..>108137)
                     /locus_tag="ACOIAP_000226"
     CDS             complement(106869..>108137)
                     /locus_tag="ACOIAP_000226"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2637150.1"
                     /translation="SISKTTANQIKSTINATQTRLNGSNRYETSLLIAKEIDKNHDVE
                     KVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTSKWLENEDLQNAYFIGGP
                     QMISTNVINKVNGITKDNVTNNRVYGADRHETNANVIKKFYTDDELEAILVAKSDVLV
                     DALAAGPLAASLKSPILITPKTYVSAYHKTNLETKSANKVYKIGGGLTSKVMSSIASS
                     LSKHNTTPADPGSNNGAKTVMIDPGHGGSAPGNSFGGMIEKDYNLNTSLATTEYLRSK
                     DINVIMTRDTDKTLSLGSRTALSNSLKPDLFTSIHYNGDNNRKGHGVEVFYKFKDKNG
                     GTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRTNNIPAVLVECAFLD
                     NEKDVSLINSPAKVKEMGIQIGKGIEDSLK"
BASE COUNT        34233 a        19395 c        11334 g        43175 t
ORIGIN      
        1 tattaaaata gagtaatagt ttaaattcta ctactctatc tataatctat ttcttaatta
       61 ttcaatctca aatttagctc ctcatcattt aaatctttca taagatttct aaaggtacta
      121 ggtttgttgc aaaagaaaga ctatggcatt aaacacttat atatctgttt ctttaaactg
      181 taatattaat attttttaaa cacgctgact tttgcttttt ctaacttctc tccatgatag
      241 ctctccccta tcaagagctt ttataaatat ttctgctgaa gctaaatttg tagctattgg
      301 aacatgataa acatcacaaa gtcttattaa agcttgtata tctgtttcat gagcctgaga
      361 tgtcaatggg tctcttaaaa aaataactaa atctatttct tgtgttacta ttaaagaacc
      421 tatttgttgg tctccaccta aaggaccaga tgctaatctg tttatattta attcagtttc
      481 atccatgatt ctttttcctg tagttccagt tgcatatagt ccatactttt ttaaaattga
      541 ttcataacct atacaaaatc cgaccatagt atttttcatt tggtcatgtg ctaccaatgc
      601 tatattcata tatctaatct cctcaattta tgtttagatg tatttaaatt tagaaattta
      661 ttttctttct tctcatacac acatttagta ctaaccctaa gttcgctaaa gatgtcaata
      721 acgaactacc tccataactt acaaaaggta atgttactcc agttactggt attaacgcaa
      781 ccgtcatacc tatattttgg attatctggt aaccaaacat tcccataaca ccaaccacga
      841 tgagggttcc ataaaagtct tttgcatctc ttgcaattgc taaaagcctt aataggaata
      901 tcataaataa gattatcaac actgccattc ctattacacc aagttcttca cctacaacag
      961 caaatataaa gtcactatct tgtacaggta aaaagttttc ttgattttga cttccattgt
     1021 aaagtccttt accagttaca ccaccagaac caattgcaat cagagattgc ataacttgat
     1081 agtttccttt tagtgttaca tcttctgggt ttagaaaagc ttctattctt accttttgat
     1141 ggtctgccat cattaaatac atcagtggca ttgacaccaa tagtatgatt attcctcttt
     1201 ttatcaactt tgaactaaga cctgctgtaa acagcattgc aaatatcata caacaaaata
     1261 caattcctgt tcccaagtct ggctgtgcaa tcaataatcc aataaatgga agagaataaa
     1321 ctataacagg cataacttcc tttaatgtat ttaatttatc ctttttggat tcaagtattt
     1381 ttgcataact tagtacaaat gttaatttga ctatttcaga tgtctgcaag tcaagtggtc
     1441 ctaaattaat ccacgaccta gctccacctt ttactgaccc aattccaggt aataaaacga
     1501 tggctaacaa aacaagactt attatataaa gagctttgta atacctgcct agaaaattat
     1561 aatcaaaaaa taatatgact ataatcattc ctatcccaag tacaaaggct aacccttgtt
     1621 taatcaattg attatatgaa cctgttgaat tagcatgtgt tgcactacta agtatgacaa
     1681 gtccaaaaat aaagatagct aatactgtaa ctataagttt ccagtctaac tgttttatca
     1741 acttaattgt cgacttataa ttaatattga tttttttcaa agaatcaccg tctttctatc
     1801 tttaaacata taattaataa aaggggcata taccaataag gatatccccc ttttaagcac
     1861 taattacata catctatctt ttatattctt tagtggtata ttagcaacta atgcagatac
     1921 aggtttgtca tcatgctcac ctctgcattt agacattttt atttcaaggc catcatcttc
     1981 tatttctgca taattagcta ttacttttaa aatgtctgtt tttatcatct ctaaaagttg
     2041 tggtgaacaa tctactctat catgaactaa aactagcttt aatctctctt tagcaacaga
     2101 cttactagtt ttagcttcgt tagaaaaaac tctaaataaa tctaacacag atgtatcctc
     2161 ctttgctact tagccatgct aaacattttt ttaagtctac caaagaatcc atcttcaact
     2221 tcaagatcaa gtagaggaac ttcttcattt agtatccttt ttgcgatatt tttgtatgct
     2281 tgaccagcaa gtgacttaga atcaagtata gctggctctc ctttatttgt tgatataatt
     2341 atactttcat catcaggaac aagacctaac aaatctattg ctaatatttc tattatatct
     2401 tgtttatcca tcatgtctcc acgcttaacc atatcatttc taattctatt tataaccaat
     2461 cttatctctt ttatttcatt tgcttctaat agacctatta ttctatcagc atctcttact
     2521 gctgatattt ctggattagt aactacaata gctctatctg ctccagctac tgcattttta
     2581 aaaccttgct caatacctgc tggacagtct attattatat attcgaaaga ttcttttagt
     2641 ttctcacaca ggtcaatcat ctgttcaact gagacagcat ttttatctct agtttgtgct
     2701 gctggtaata aatatagatt atcaaatctt ttgtctttta ttagagcttg cttaagccta
     2761 caagttcctt caactacatc tactatgtca taaactattc gattttcaag acccattact
     2821 acatctaagt ttctaagtcc gatatctgca tccactacta ctgttttttt attttctagg
     2881 cttagcgcag ttcctaagtt tgctgcggta gtagtttttc caaccccacc tttaccagat
     2941 gttataacta taacttcgct cataatacta ccccctattt ttctttctat ttgtctaact
     3001 ttgacaaata gctttcgatt acaattcttc cattacttac aaaggctatt tctgggctaa
     3061 tttctgattc actttcataa ttttcttcat catctggagc ttctgcaata ttatctgcta
     3121 tttgtaatat tttaggatta agatttccag caacaacata tgcaaattca ttaccttctg
     3181 cacctgcatg tacaaaacct tctattttgc ccattacaaa aacattacct cctgctacaa
     3241 ccttagcacc agcatttata tctcccataa caactgtatt tgattttgaa aggacctttg
     3301 aaccaggttt catatcattc aatataacta catcaccttc aaattcaata ttttcaccag
     3361 atcttagggt attgacatat tttgttggaa aattactatt ttcttcaact ttttgatctt
     3421 caacaaattc cacatcaaat ctagaagtaa ttccttcttt cagttctaga atttccatgt
     3481 cagttaaaca atcactgtta attttactaa ttttagcccc attaaaaaag ccaacatatg
     3541 cttccaattt gtttattatt ttttcctgta tttcctcaaa tggagcttct ctttttatat
     3601 ttactattat ccctctttta ttacccttga actctactag ttcttgacta caaatttctc
     3661 ttaaagacat aacaacctcc agagtgatat atcatttata ttcttcaaat acgctttaaa
     3721 cccttttatt ttttctatat aaagctaaag tttatacatg gattgagcta tctattaatt
     3781 tgtgactcga aatttatatt ttcgtcagaa gaattgttaa catcattcgt cttgttgtca
     3841 tttttactat tagttggctc taatcccata taagttccaa taacttctct agttggtaaa
     3901 agtgagaata cacttgaatc accttgagga attacacata caacagctat ttctgggtca
     3961 tctgctggag caaaagcaac agtccatgta aaagaaccat aatcttgctt aaatctatct
     4021 atttggtcat ctgttatttt gggatttaat tcttttatag cttttcttag atatgaagaa
     4081 tttaccttat cggtgtcctc taatctaact tttactccat cttctaattc ttcctctaat
     4141 ttttttcttt cttcgtcttt caaatcttta ttttctaatt tcttttttat ttccttttcc
     4201 ttagctaaag aaagctcttt ttctttttct gctttcatct tatcagctag tttaattgca
     4261 tcatttaggt taacattata agatgacata tgacttttta aatattcata ctcattatct
     4321 gtaggtattt tcccactctt ctcagctgta ccagtttttg ctgctacatc tattgggaaa
     4381 tcagcaaagg cactcttagc tgtaccttgt cttgcaacca atttcatacc ttttgttaat
     4441 tcttttaagt tatctggatt tttaaaaggt attttttcta ctttcttctg gtcattaatt
     4501 ttaactgatg aatagtcact tgaaacagct ctatcaacta cagataattc tactagatta
     4561 cctccatttg ctatggcagc tacatatctt gatatttgag ctggtgtata agcattttca
     4621 ccttgaccta tagctaagtt gaatgtatct gcagtactcc attttgcaaa gttaaaataa
     4681 ctgaatactg ctaaatctgc tacatcttct attctatctt ctttaacatt cattttcttt
     4741 agcctattca ttgtttcaac tctaccagga gttttctttt ctgctgccca acttacaatc
     4801 tcattaattc ttttctcata ttctttagga tttttttctc tagttatatc aacaaaatca
     4861 tttgccattt ctctttctaa attcgacttt agaagagctt gtgttgattt caatttatct
     4921 tctgtgctag gaactttacc tgctctttct tctacttcat cttgaagacc tgtattttga
     4981 tcaagtccaa ataattttgc atactcaagt attttatttg cattcatatc tataccaatg
     5041 ctttttccat ctggccatgt tttacctgta ccaattgttg ccatatatat attacaagac
     5101 tcttgtattg ctttatataa gtttgtcata ccatggtttc ctctaccatg gttccataca
     5161 tagtcaccaa aagatttttt acctaacatt ataaccccag ggtcatttat agtaaagttt
     5221 ggattcaaac cattctctaa cgctgccatt gaagttacca tcttaaatga agaacccggc
     5281 tgaaattccc cttgtgtaac caagtttaaa agtggacttc ctgctagtaa gtcatttgga
     5341 ttttttggtt gaagtgcttt ataatcttct gtagaaattc cttttgcaaa tttatttggg
     5401 tcataattag gataacttga tgaagctaat acttctccat ttttaacatc aatagctata
     5461 agagctgctg attgtgcttt tcctgcatat gcactaattg gtttgtcccc aaatttactt
     5521 ttaaaggtac cacccttaga agcaacttcg attatctgtt ttaatgcatt atctgaaact
     5581 tcttgtaaat ctttatctag tgtaagatat acagtatctc ctgatttagg ttttttagac
     5641 tcaatttctt tactgattct acccagtgca tcaactttaa ccattttata accatcagtt
     5701 cctcttaatc tactttcatt actcttctct actcctgcaa gacctaccat atctccagtt
     5761 tcatacccct tttgaaggta tgattctatt tgagtggatg gcatttttcc tacatatcct
     5821 aacatatgag aagctaatga cccattagga taatatctta ctggttctac tgctattgaa
     5881 acaccaacaa ggtccatagc actctcttca atttgagcaa ttgtagtttc tcctacatcc
     5941 ttcgcaatag ttactggatt atattgagag tatccttttg attttatcaa atctcttaca
     6001 accattattt ttcttgcatc ttcatcactt aagtttttat caatttctaa tgcatcacta
     6061 tttcttactt tttcaaacgc ttctttggca cttagtttag tttcttttat cttataacta
     6121 gccaaccaat ctctcttatc tctttctgct gtgaacatcc atttactaac taaaataggt
     6181 ggataatatc cattttcatt tagttttgcc tgtaatcttg tcgcatccaa tcttttatct
     6241 tcttgagata atattccagc tgatataagt ttatctacca agtaataaaa actttcctta
     6301 gcattataat catttggaat accattttct gacttatatt ccctaatatc tctgtcatat
     6361 gtataatagt actttccatt ttctacatat ataggaaact catctacata ttcttcacca
     6421 tttctctcca gcaaatttat aagttttaat gatatttcat ttgctcttga atgcttattt
     6481 gcatcttttt tattaatatc gttacctgaa acttgaacag taaataagtt tttatttcct
     6541 gccaacagtc ttccatatct atcttttatt tctcctcttg gagcttctat tgccaacttt
     6601 ttatatgttt tattctcagc taactcattg taatattcat atttaaatgt agtcatatag
     6661 attattttta ctaaaatagc taaaaatatc acgctcatga ctatcttaat tatttttagt
     6721 ctatcaactt gtttattttc ttccatgaaa tcaccaacta atcttcttta agttttaaaa
     6781 ctgctctttt agataagcga tatattacta aaccaattaa actattcact attggtgcta
     6841 ctagtaaacc ttttataaaa agtgttgata tattgtagct ttgataaatt atactagatg
     6901 tacctatatt gacaattgaa tcaattaaac tgcctataaa aattaaaacg aaagtaataa
     6961 tataactacc tttatatagc tgatctctca tgtacccaat tgcatatgca ataataaaca
     7021 aaattaatgc atttgcacca aaaattccac caacggttat gtctttaata agccctatta
     7081 ttgctgctat aatcccacct tctaattcat ccaaataaag agagattatg gttacatata
     7141 taagaactaa attaaagctt atgccaaaaa tatctatata atttgttata ctattttcta
     7201 tagtcataag cacaatcccc aacagacaaa gtaaaacttt tttcattgtt tttatcccct
     7261 ttatcctata tttcttggtt ctatgactac aacgtcattt atattcttaa aatcaacata
     7321 aggttttaca actacatatt ttaatgactt atctttatca tcaaccactt tttcaacttc
     7381 gccaattggt ataccatctg ggaagaatcc aagacctgat gttgttatta tatctccttg
     7441 aattacatta tatgatgagt caaacatata tccttgcaaa tatcctttac tattataact
     7501 atctttatta tctaaagtag tattttgagt aattgtacct ttagcattgg catcctttgc
     7561 tagtttaaag cttacagatg ccttagaatc caatagtgaa attgccttac tataattgtt
     7621 ggaaacttca taaactatgc caactaaccc actaccattc ataactatac tttctttttt
     7681 tacacctgaa ttttttcctg cacctatgac aaaactctca taccagtttc catcattttt
     7741 actaacaaca cttgttgaaa tacttgtcgc cttatactct tcttgtacaa agttaagtgt
     7801 cttttttaac tcttctagcg attctgtttt atctagtttg gcatttaaag atatcatatc
     7861 ttttttaagt ttttcatttt cttcttctaa tttttttacc tttttagaat tatctttaaa
     7921 atttgctatg tctttaaaac catttttgat aaaagaaaat ccatcattta ttcctttacc
     7981 tacacttgta atagcatctg aagctactcc taaatttact gggctaccac tagaaaattt
     8041 accaattgat atacccacaa ttccaattaa agtgatagca actacgcccg ttgctatcac
     8101 tttaacatta atcctttttt tctcattttt gttcttgtca aatctcaagg ccatcaccaa
     8161 cttctaattc ttagtattca tcattaatac tttttcaaag atttcttggt cttcaacaga
     8221 ttttcctgtt ccaagtgcaa cacaatcaag aggtgtttct gctatttgta cagacatacc
     8281 agtttcttgt gtaataagct tatcaagacc tctaagcaaa gctcctcctc ctgttagcat
     8341 tattccgttt tccattatat ctgatgctaa ttctggtgga gttctttcta gtgtagattt
     8401 tattgcatct actattgaac ttacaggttc ttttaatgct tctctaactt ctgtagagca
     8461 tatttctatt gttttaggta atcctgagat taaatctcta cctcttattt gcatatttac
     8521 ttcttcatca tctttaaatg tagagcctat gttaattttt acattttcag cagttctttc
     8581 acctatcata aggttatatt ctttttttac ataagccact atagactcat caaattcgtc
     8641 tccacctatt cttatagatt tagcagtaac gattcctcct aaagatatta cagctatttc
     8701 tgaagtacct ccaccaatat caactaccat attaccttct ggttcttcaa cttttaatcc
     8761 agcccctata gccgctgcca ttggctcttc tataaggaat gcatctttag ctcctgcttg
     8821 tcttgcagcc tcttctatag ctctcttttc tacttctgta actccaaaag gaacacatat
     8881 agctattctt ggacttacaa cacctttttt atcagccgct ttttgtataa aataactaat
     8941 cattgattga gttatgtcaa aatcagctat taccccatct ttcataggtc ttatagctac
     9001 tatatttcct ggtgttctac ctatcatttt tttggcttct tcacctactg ctaatacctc
     9061 tttactgtca tctcttattg cgacaactga tggttctcta acaacaatac cttgtccttt
     9121 tatgtaaact aatgtatttg cagtccctaa atctattccc atatcctttg tcatcttatt
     9181 aaaactaaaa aaaccttttt tttctttctt tttttcctta gccatgattt tactccttcc
     9241 tactattaag aatcatgttt aaaacattct cttcttattt tatcacatat aaagttaaat
     9301 tatcatattt tctttaaagc taaagtataa tccatctcca ataattatat ggtctattat
     9361 ttctattcca attatttctc cacatttaat aagtcttgat gtgatatttt tatcttctct
     9421 tgatggttcc acacttcctg aagggtgatt atgcattact attatcttac ttgcacttct
     9481 tcttatagct tctttaaaaa cctctctagg atggactaat gacgagctta aagtccctac
     9541 agatacatct acatcagata ttatctcatt ttttgtgttt aaaagaaccg ctttaaaaac
     9601 ctcttttttt aaatacctta ggctatccat ataatatctc tgtatatccc aagggttcct
     9661 tattttatac tttataggtt taaaactagc tactctagag cctagttcta aagctgcttt
     9721 aatttgggtt gcttttgata acccaattcc atctatatta cacagctcct ctattgtcat
     9781 atcttctaaa tgtctaatac cctgaatatc tctatttatt atatagttgg ctaattcaat
     9841 agcattttta ttcttgtcgc cagttcttaa aagtatcgcc aacaactcag catttgataa
     9901 gctttttacc cctttggcaa gcatcttttc tctgggtctt tcctctggtg ccatttcttt
     9961 taccttaatg gttgaattaa atgacttttt cagacaaatc acactccata aaaaagattt
    10021 atactaaaat atttttttaa taggtcgctt aaccttgaaa ttggaagacc aactatatta
    10081 aaataatctc ctctaatttc ttcaactaac aaagctccat atccttgtat accataagct
    10141 cctgctttgt caaatgactc attagttttc agataatcct caatatcttg ctctgataac
    10201 gttttaaatt tcacattgct gattacatag tcaattacct ttttatcttc gcacaagttt
    10261 attaagctaa tacctgttat gacttgatgc tctcttccag atagtctttt taacatatct
    10321 cttgcacaag actcatcttt tggttttcct aaaatagcat tgtctaaaac aacaactgta
    10381 tcagctccaa taacaacatc ttcattatgt tcagatgcta cagacatact tttttcaaaa
    10441 gctaacctca taactaaatg ttttggtgtt tcaccttcca atataatctc atcaatttca
    10501 tttttaatta tatcaaatct tacatttgta ttctctagaa tttctttcct tcttggagag
    10561 gctgatgcca agattatatt catttattca cctcatttgt acgtaatttg tacctattta
    10621 gtctatcact atattgtaaa aaattcaaca gaaatgtcga accttttttg ttacactatt
    10681 gttatattta ttaccattag aataaatata cataaaatag aggtatggaa attattccat
    10741 acctctgttt tatgtactca ttagagatat ggaaattatt ccatatcttt attttgtcca
    10801 tattacaaaa ttttaatagc tttctttgga catttttcca tacataaatg gcatcctaca
    10861 catttatctg catctacctt atgtttttct tttaattctc cctctattgc atcaaactta
    10921 cattgttttt tgcacactgt acatccaaca caaagttctt ggtcaatagt aactttcttt
    10981 ttcttagtta tgtcacctga tattactttt gtagggcatt ttgctacaca ttgcatacaa
    11041 cctacacatt tattagggtc tatcttagct attttgtctt caaatattat tgcatcaaat
    11101 ttacaagctt ttacacacat tccacagcca atacatccag cagtacattt ttccttaaca
    11161 gctttaccaa actctttgct attacactct acaactactt cttgactctc tggttttgtg
    11221 attattatac ccttagggca aacttcttta cattttccac aatttacaca cttttcttca
    11281 tctattactg ctactccatc aactatagaa atagcatcaa atttacaagc atctttacat
    11341 gttccaagac ctaagcatcc aaatttacac atcttggcac ctgagtttaa aacatttgct
    11401 gctctacaat ctgatattcc ttcatactca tatttatctt ttgcacttga acaagttcct
    11461 ttacaaataa cttttgctac ttgtttctca cctgcttcag cgcttattcc cattatttct
    11521 ccaacttttg caccaacatc tgctccacct acagggcaac cattaactgg tgcattgcct
    11581 tcaactatcg catttgcaag acctccacaa cctggaaatc cacaacctcc acagttggct
    11641 cctggaagta ctcctagtat agcttccact ctctcgtcta cttctacagc aaacttttta
    11701 gatgcaaaat ctagtactat cccgaagatt aagcccataa ttcctaaaac taatacagct
    11761 gtaagtatca ccattttcac ccctcttttt tatagcttta taagtcctgt aaatcctaag
    11821 aaagctattg acattaaacc tgctgatata agcgttatag ggaaaccttt aaatgcttct
    11881 ggtatatcag ctaattctag tctttctctt atacctgcga atattactat tgctaaagta
    11941 aatccagctc cggctccaaa tccatttatt attgtttcta ctaaattata acttttttga
    12001 acattaacta gagctatacc aagaactgca cagtttgtag ttataagagg taaataaact
    12061 cctaatgctt gatataaaga tggactcatc ttttgaatta ccatttcaac gaactgaact
    12121 atagaagcta taaccaatat aaaagctatc gtttgtaaga atccagttcc agtttttact
    12181 aataaaatct gtataaaata agttataatt gaagctagag ttaaaacgaa tgtaactgca
    12241 actcccatcc ctactgctgt atcaaccttc ttagaaacac ctaagaaagg acatatacct
    12301 aagaattgag atgttataac gttattaaca agaacgatac ttaaaaataa aagtattaaa
    12361 ttcatttatt acacctccac tatgcttttt tacttcttaa tttattaaat cctgcaaata
    12421 agaatcctaa tgttaagaat gcacctggtg gtaatataaa tattaatact ggttggaaag
    12481 atgctccaaa taatgtcatt ccaaataaac taccatttcc aagtaattct cttactgcac
    12541 ctattattgt aagtgcaaca gtaaatccaa gcccttgacc tacaccatca actattgaag
    12601 gcatagcccc tgttttgaaa gcaaaacttt ctgcacgagc taatattaaa cagttaacaa
    12661 ctattaatgg tatatatata ccaagagcct tatcaagagc aggaacatat gcttttaaaa
    12721 gcatacctac tattgtaaca aatgtagcta taactactat aaatataggt attcttatct
    12781 tatctggtgt aatttttctt attaaagata taactaaatt tgcacatatt aaaactgctg
    12841 ctgttgaaag acccatacca attccattta ttgctgaagt tgtaacggct agtgttggac
    12901 acatccctat aacttgaaca aatgttgggt tctcatctat tagcccattt ttaaatactt
    12961 tagctaaatt cataattaac cctccttatt tattaagagc actattgaaa acatctatag
    13021 cagcatttac tcctgtagta actgctgtag atgtaatagt tgcacctgat attgctaata
    13081 tttgattatc tgctgttgta cttccttttg ctacttcaag aggttcagca gtttttcctt
    13141 tgtattgacc tttaaatgca tcatccttag ctttcgctcc aagacctgct gtttctgaca
    13201 tgttaccaat gtcaacacct gtaacttgac cttcagatga gatacctacc ataacttcaa
    13261 tttctccacc atatccactt ggtttagctt ttaaagtgta cccaaccact tcagaaccat
    13321 ctaaaccttc atacacttca gctataagac catctccaag gtctttatat gtacttttat
    13381 ccatttcttt aaattctttt gcttctggaa gtactgcttt tctaagttca ttatttgctt
    13441 gtatatttct ttgttctatt actggagctg taacctgatt tgtagctcca agagctaatg
    13501 cagctattgc acttatagca agtaaagtac cacctaatct caccatactg ttcattattt
    13561 agccacctcc ccaaatactc tatttctaac aaacttatct ataagtggag caagacagtt
    13621 cactaatagt attgagtaag atacaccttc tggatatcca ccatacattc ttataacagt
    13681 tgttataaga ccagctaata cagcatatat tatttgacct tttttagtca taggcgaagt
    13741 tgtataatcc gtaagcatga agaatccacc taacataaga cctccagcaa acagttgata
    13801 tattgcgaaa gttatattaa atccacctaa aaggaatgtt aatataaata cagttgctat
    13861 gtaaaatact ggtataacat aatttattat gcctttatac attaggtata ctccacctaa
    13921 taataataat attgctgatg tctcacctat acatccacca atattcccta tcatcatatc
    13981 agcaagacta attccattgc tagaaaggtc cgctagtcct gctgctccat ttttcaaaaa
    14041 gcttaatgga gttgctgtag taactgcatc taaattttta cctatccagt tgacacctgg
    14101 ttgagtccaa gcagtcattg ctactgggaa tgatgctaat aaaaatgctc ttgcagcaag
    14161 tgctggattg acaaagttac atccaattcc accaaatacc attttaacta ctaatattgc
    14221 aaatattcct cctactagac acatccacca aggaagtgat gctggtacgt taaatgctaa
    14281 taataatcct gttacaacag ctgaaaaatc tcctatagta cttttttgct tcgcaaattt
    14341 ttgatataaa aattcagtac ctactgtacc aagtatacaa aaaaacatag cactcaaagc
    14401 attaagtcta aagaagtata ctcctgctac tgctgctgga aggagtgcta taataacttg
    14461 tttcattata tatgaagtat cttcattact tctcacatga ggagaagatg atactatcaa
    14521 cttattttcc atcgtttttc ccccttaact ttctttattt ctgagcagct tgctttcttc
    14581 tctttgctcc tatttctctc tttgctgatc ttatagattg aagtaatggt cttcttgctg
    14641 gacaaataaa tgaacaagac ccacattcta tacaatccat tgctctatga tattcagctg
    14701 tgtcatagtc atcttttaaa gaatatgcac ttatgaaaag tggttgtaag aatgatggac
    14761 atacatctgt acatcttcca catcttaaac agttttgaac atctggagta cgtgattctt
    14821 cttcatccaa acataaaatt cctgaagaac ctttgttagt cgctatttca gtagtatatt
    14881 gagctattcc catcataggt ccacccatta taaccttacc aatcttctta tcttctttaa
    14941 atccaccaca ttgttctatt atttctgaaa ctaatgttcc aacttttgtt attaggttct
    15001 ttggctcttt gatgcaacta cctgttactg tagtgattct ttctaccaaa ggcatacctg
    15061 ttttaataga cttagctatt tgtgctgctg tggcaacgtt gtcaacaact gcacctgctg
    15121 ctattggtaa tccaccagat ggaacttctt tgcctgtaca tgcgtaaata agttgtttct
    15181 ctgctccttg tggatatttc acttgaagac caacaacttc gatttcacta taatctttag
    15241 ctacattttg aattgcttct atagcatctg gtttatttgt ttcaattcct ataaatcctt
    15301 ttttaacatc taataccttc attaatgctc ttaaaccaaa tacaacatct tctggatttt
    15361 caaccattaa tctgtggtct gcagttaaat atggttcaca ctctgcacca tttaatataa
    15421 ctacttctgc cttgctatct ggtggaggag atacttttac atggttagga aatgtagctc
    15481 cacccatacc tactattcct gcctctttta tgatacctac tatgtcttct ttgctcaaat
    15541 cctctaactg accttttggt tgaacactct catgtaattc ttccttaaag tcattttcga
    15601 taactacaca ttgagctgaa ccacctggta cttcatgttg ttcaatagca ataactttac
    15661 ctgatactga agaatgaacg ttacatgaaa caaaaccttg ttgttcacct attttttgcc
    15721 caaactttac ttcatcacca acttcaacaa tagttttagc tggtgcccct atatgttgct
    15781 gaagaggaat gtaaactatc tttggagctt gagctttttc aagtgccttt gtgttagagt
    15841 actcttttct atatggagga tgtatccctc ccttaaaagt taagagtttc attgttttac
    15901 ccccttatct ataaaaaaac attttttctg ccttctataa gtatactata tatattaaaa
    15961 aatcttaaca attgttaaaa aaatatccgt atttttataa tttattttat aaatcaatgt
    16021 ctctatatta agtcaaatcg aggaaaagga ttgcttaatt aaacaatcct tttcattcag
    16081 ctttctaaag tccaaatttt ctgtatttta ttttatagaa tttataaaca tagagtactc
    16141 ctgcatagat gataaaagta gacttttact tacactatat ttttcttcat ttgctgcttt
    16201 tgaagctgta tcaatttttt cattcacatt ctttacatac tctattaaat tatctttaaa
    16261 taaacgcatt tcagaataat caattttttc agcttctttt gatatatttt gtgatattgc
    16321 ctttctattt gtcaaaatag tattatattt ttccatatct acattatttt cagcattcga
    16381 ccaaaaactt gattcttctt taaagtttgt tattaattta tttaattctt tagatatact
    16441 atctatataa gcatagttac ttgtatactc taaagataac ataggtgcat ctaagtgtga
    16501 taaaaatgca tctggaaaca cctttcttac actgcttatc tgctttctaa catcattttc
    16561 atcaaaagag gaatatgtct gtattttttt tactccatcc ttctccataa ctgaaaaagg
    16621 tatatcattg ttaactaatg atgtctgtat ttttttcaaa tcatcattat tatctattgc
    16681 agcaacttga atagtgtaca tatcccagcc ttctatagta gctaatttaa cttcttctgg
    16741 ctctttagtg ttatttaccg ctttttctgg attagtttct tgtttatcat ctgaattggt
    16801 ttgtgattta gatttttttc cgttttttat tgaatttaat tcatcagata tatctttata
    16861 agttatatct gatgaattat ttagaaatgg tattttagcc gatacatact ccaatatctt
    16921 gctatctttt atttttgtat aagaataata gccaattaga cacaagcaag caatcgttat
    16981 aacatattta cgtaaatcaa tcttatgtct attattatta aatcctctgt atatcgtttt
    17041 tcttctattc attagtttgt ccctcccaaa attatattat taataaagta tatttttaag
    17101 agtcacaatt tatgaatata aataattatt tattctaatt ttttaataag aaattgtact
    17161 tactaaacaa atcttcttgc accaagtaat actttagacc aatatgaact agttaaatta
    17221 tccactttaa ccttattagg attagtttga gtaccactac aatgaataaa tttactattg
    17281 cctacatata tacctacatg attagttgtt ccatcaccat cagtatcaaa ataaactaaa
    17341 tctcctggtg cataattccc catagaaatt gcacttccaa aattagcctg ttctctagaa
    17401 actctaggaa tagaaacgcc tacagaatgt ttaaaaacat actgtgtaaa tccagaacag
    17461 tcaaatttat caggtcctga agctccccat tgatatggta ttccaataag agtatatgca
    17521 aaatctacga ttgttgaacc ttttgctgta gatttatctg aatttccagt aaatgatggc
    17581 tttgagttat tattagattg agaattttga ttagatgatg aatttgaatt ttcttttgta
    17641 ccttcattag tctcagaaat ataactgcca ctcacccatc cagttgttcc attcgatagt
    17701 tttaccttat accaaccatt atttttagct tttaattcaa caacatctcc accatttaat
    17761 tttcctatta tagaatagct tgtcccagga ccacttctta catttaaact cacagtagat
    17821 gttaccttac catttttacc ttcaattgat tcttcgctag atggtttttt atcagagtta
    17881 ttagtactat ttgaattact ggaattattc gctccaacat cttctgacgt tttagagata
    17941 tattggctac tagcccatcc agtaacccca tttgatagtt ttattttata ccatccattg
    18001 ctttgttcta gtaactttac tacttctcca ttatttgctt taccaactaa tgaatagtta
    18061 gtacctgcac cacttcttac attcagtcta gagctcacat ttactttacc atttccactg
    18121 atagttgttc cacttgaagt tgaattattt ggatttgatg taccttcaga tgaaccactt
    18181 gttgatatgt attttgcact tccccatcca acaacagagc ttgataccct tactttatac
    18241 catccattag atttttctaa aatctctaca gtttttccct tgtacaattt tgctacctta
    18301 tcgcaatcag agcttggtcc acttcttatg ttcaaggcac ttgctgttac tgttcccttc
    18361 tcaagagcac ttgcatttat ggagctaaca gatactgcta ctgccccaat tcctaaagcc
    18421 gctatagctt tcttcactac tatcactccc cccaacaaat ttttatagtc ataaatccat
    18481 aacattatta tccattttta gtacctataa tttaatgata acttattctc ttattaattg
    18541 taaagaaatt ataaacatat ccttaaaatt aatgattttt aggaagtatt tcaatccaat
    18601 aattatctgg gtccgctata aaataaattc ccatactttc attttcaaaa catatgcaat
    18661 ctaaatcttt atgaagtttt tttgcctcat caaactcctc aacttctaaa gccagatgaa
    18721 attcattatc tcctaaatta tatggtctgt cccaatctct aagccaagtt aattctaatg
    18781 tatgactagt aatgccatct cctaaataaa ctaatataaa acttccatct tctgcttcct
    18841 tacgctttac ctctttaagc cctaaagctt ttttataaaa atctaaactt ttttctaagt
    18901 tagtaacatt gaaattgtta tggcaaaaat taaacttcat tttgaaatca ctctccaatt
    18961 tttatttttt tatattatat cattattata aatttattta aatcatatta agctaaaaat
    19021 ttgaacgatg ataaacaatt accagatact ggtaaattat ttaaaggaat atgtcaaaaa
    19081 aagaataagc tctttcaaat gcataaaaga tttataccta agttatactt aatcatgcaa
    19141 attgacagaa cttattcttt aaaactttaa cttttaagtt tttctttgat gatataattt
    19201 attacttttt ttctaatatc ttcagcatta taatcatctt ctacttctat atccaaaagt
    19261 tttgctattg acctcatatc ttctctagtc tttgacctat agcttgatat taattcatct
    19321 tttattttct caggctctaa aagatattct tcatctcctc ttttgaaaac aacgtatttt
    19381 tgagcatatg aacttctatt gtagtatata tatcttgata tttttcttaa aatttgatta
    19441 tatgaaagtc gcttgttaat atcaagtttt aagtactctg aaaaagcaaa tagctctttt
    19501 tttgatttaa ataatgcttc tttctttata gtccttgata ttgaagttac actttcttga
    19561 tatgcacact tttttaacat ttttaaatat actctattaa gaccgatact ttgattgaat
    19621 ttttttatat tattattaat aatcttatcc aagttacctt caaagtattt ttttgctcct
    19681 ttttgtgata cataactctc aagttctttg tgggccatat caagtatcat tttttttaaa
    19741 tcctctttat atcctctaga ttccatgata ctccctccct tagctattta tagtatattc
    19801 aaaaagctca agaaatgtga gtcattacaa atttttttta ctttttatgt atatattaat
    19861 ttaaaagggg agataatagt aatgtaaaat caaacatact caatctcccc catttttaga
    19921 cctctattac tcccccaata gaggtctttt tttagtttat taacttctat tcaattccct
    19981 ttagttcaaa tcctaattct gctattactt cttttaattt ttcaatagat acactatctt
    20041 tcatatctac agatgcacac ttgttttcta aatctacatc taaaacttca ataccatcta
    20101 tatcttctgt taatgcagtt ttaagatgat ttacacaatg accacaactc ataccttcta
    20161 ctaatagttt cttcttcatt taattacctc cttataccct ataagggtat tttatcatat
    20221 agtttatact tttaaaatag aaattaatca tttaatttga ttcattcgat tttatatcta
    20281 gattagatat tccctcatat acatcaaaat catttggagt aattttacct tttaatctac
    20341 tactacttac aatatagttg tttctaacag ctaaacttat aaatgttgca ttatctttta
    20401 tatatgtctg tacatctttg tatgcttttt ttgtttcaat ttcagatgta gaacttgtaa
    20461 gtgcagacat atatccattt agcttatcat cagtatatcc actactagct ataatactac
    20521 ttgcatctgg tatacttgat aatttccatc caactaatgc taaatcataa tctttagaat
    20581 taagagcatt ttccatgtcc ttatctgaca gctgatttac tgtactattt attcctatag
    20641 cctttaagtt ttcatttatt atgtttgcag tttttattct ctcactatta tctctgttta
    20701 ctattatttt taagttcatc tcagaaagtt ttttctttac ttcctctttt tctctatttt
    20761 gtttctcttc agcttctttt ttgatgctat cttcttccgc ttttttagct tttgcttctt
    20821 cttctggagt aagcttcttt aaattctttt tagctggttt tttctgattc tttattttat
    20881 tgtcattttg atttactgga tttacatttg catattctac cttagcaagg cactctagtg
    20941 ctttatcttt attaaactct aaatccttca tttcactatt atagtatttt gattttgaat
    21001 taagtggaaa attaactgga gtagcatcat ccatataacc ttcactaata attctatctt
    21061 tatctataga gtgcgcaatt gcttttctaa aattgacatc tttaaaaaaa ggattattat
    21121 aattaaataa tacacactca taatctctac cttgatattt tgttatatta aactcttttt
    21181 cttgaaactt acttaaatca tttaatgtaa cattggttat atcactatcg agagccataa
    21241 ccatagatgt ccttgcatct tcattaggca ccatacctac ttttatgttc ttcatggtct
    21301 ttggaacttc ttcatagtag tctttgttta cagataaaac cattccttct ctttctgtat
    21361 atgattctat tttatatttc ccatttccta tcatattatt attcttgtca tttacatctt
    21421 ttgaatctaa atgactttga gatactattg gaaaaattaa actatcaatt gagaaagcat
    21481 atctagcttt aaattttatt gtaaaatctt tatctgattt aatattcaca gaagctatat
    21541 ttttggtaaa ttcattatat ggactatctg cacttttttg aattaaacca atagtatagt
    21601 ttacatcatt tgaagtaaca tcttttccat catgccactt tgcatctttc agctttatat
    21661 ctatactcat tccatcctga gctatattat actccttaac taattgagga attacattgt
    21721 agttctcatc tatagtaaat aaactatcat aaactaaatt cattatataa ccaacagact
    21781 tatcagtatt agttatagga tttatagttt ttggagttac cattgttaag tttatatact
    21841 tagcatctat agaactttga ctttgtaaac ttgaatcact actactttgt tttgttttac
    21901 tattactaca accaaccacc ataagagtta tagctaaaac aactgttaag acttttattc
    21961 tcttcattag ttttttcctt tcttgccata tatcttatta tattgttcat aattattttt
    22021 tactttttct acatattttg aagtttgctt aaaaggtata tcatgtagat tttcgccatc
    22081 tttactatac tcattatttt ctaaccattt tttcacatta cctgaaccac cattatatgc
    22141 agctatcact aaatctaatt taccaaattc tttgtataac ttacttaaat accaacaacc
    22201 aagtcttata ttagtctctg ggtcgaaaat atccacattt tttagattta attcctctgc
    22261 tccccaatct ctagttatgt ctaatatttg cattaatcct tttgcttctt tttttgaaac
    22321 agcagaacta ttaaacttac tttcggcttt aataacactg taaactatat tttcatctaa
    22381 attaaattct ttagaatact tttctacata ttctgaatat tttttaggat ataaaaattt
    22441 atgtattact ttgctttcca ttaatagtgc tccaaataag attataaaaa tagatagaat
    22501 caatactttc ttactattca cgccaattct ccttcatgta ctcaataaat ttatgtgctt
    22561 tactttctaa ttcagttatt gttcccgaat tatctattat ataatcacca tatttggatt
    22621 tttcttcctg actcatctgt gaatttatcc tattaagtgc ttcctgctca ctgcaattat
    22681 ctctcttttg tattctacta atttgtactt cttgtttaca agtaactact agtagcttgt
    22741 caaccatatc taaaaaacca ctttctacca atattgccgc atctaatact actatatttt
    22801 cgcctttttt tctcaattct tctatttcac ttattatttt ttctcttatt cgtggatgtg
    22861 tcaaattatt taacttctta agtttttctt catcactaaa aactattttc ccaagagctt
    22921 ttctatttag agttccatca tcatttttta tactttgccc aaaatggaca aatacttttt
    22981 ctaataacaa cttatcctca aatatcttcc tggatataat atcagcatcc actatagaaa
    23041 tgttaagatt tctaaatata tttgataggc tgctttttcc acagcctatt cctcctgtaa
    23101 gtcctaatat caacataaaa tcacctactt tgtctcatac caagaactgc ctacatttaa
    23161 atctacatct aagtgaacat ctatatttac agcattttcc atttcttctt ttactatttt
    23221 cttaactata tctatttcat catcaattgc ttcaactatc aattcgtcgt gaacttgtag
    23281 tataagtttt gatttcaaat tgttctcttc caatttttta tgaacattta tcatagcaat
    23341 ttttattata tctgctgcac ttccttgtat tggtgcattc attgcaaatc tctttcctct
    23401 atttctttcc ataaaattgc ttgactttat ttctggtata tatcttcttc tgtttaaaat
    23461 tgttacagca tatccatctt cactagcctt ttctactgtt gtgtccataa actcttttat
    23521 tttatggtat ttagcaaaat aactttcgat atattctttc gcctttggaa caggtatatt
    23581 taaatcatca gctaagccaa agtcactttt accatatata ataccaaagt ttactgcttt
    23641 agctgcacct ctcaattcac tagtgacatc ttccatagga acattaaaaa cttgtgaagc
    23701 tgttttagta tgaatatctt catgatgttt aaatgcttct atcatatttt catcctgact
    23761 catatgtgca agaactctta gctctacttg tgagtaatcg gcatcaacca acttacagtt
    23821 atcatctgca ataaacactt ttcttatttt tctacccatt tccattttta taggtatatt
    23881 ttgaaggttt ggttctgtag atgaaattct tcctgtagtc gttatagttt gattaaatga
    23941 tgaatgtatt ctattacttt ctggatttat tatatttaaa agtccttcaa cgtaagtaga
    24001 atttaatttt actatttgtc tatactcagt tatcttatct attattggat gcttatctct
    24061 taatttttct agaacatctg cattagttga atatccagtt ttagtttttt taattattgg
    24121 aagctctaat ttttcaaata atatgacacc caattgtttt ggtgaattta tattgaatgg
    24181 ctctcctgat aattcataaa tttccttttc taatgtagct attatttctt taaactctac
    24241 actcaattca tccaatatac ttttgtctac ttttatacct tcatactcca tatgtcctaa
    24301 tacttctact aaaggcatct ccacatgata aaaaagacca tccatactca tatccattag
    24361 acttctttcc atcataggaa ctgtttcttt aactgtgcat attatttgac ccatatactc
    24421 agctaaatcc tcaaattcta aatcttcata gtttttagat ttaacacctt ttcctaataa
    24481 ttcttccttt gatttaacct tttttgataa atatttcata gctattgcac tacaatcata
    24541 tgaagtagat gaagttgaat ctattaagta ctcagatatt gttatatcaa aatacatatt
    24601 ttctaagttt atattatatg gttttaaaga tatataatca tcttttaaat tatatccata
    24661 ctttttgatt tcattatttg aaaatatact atctaacttt gacacttcat ttgaatctac
    24721 ataatatatt ttttctccat ctacacttat aaaaatatat attatatttt tttcaagtat
    24781 attaccttgt cctctaacag tttttaaaat aacttgtcct ttttcattta cttcatctat
    24841 aaatttttct atatctttta attttaatat ttctattttt tcttctactt gttctgtatc
    24901 atttgaatcg accaaatcaa ctagccttga caaaaggctt gtaaatccaa aatatctaaa
    24961 tttatctaaa agttcatctt tatcataatc gccaaaaatc atactttcta aatctacttc
    25021 tattggcaca tctcttataa ttgttgcaag tcttttactt tgaatagcta tttctttatt
    25081 ttcctctatt ttctttttta cactgccttt aagtttatct gtattctcta ataagttctc
    25141 tatactagaa aactctttta taagctttat acctgttttc tcaccgattc caggtactcc
    25201 aggtatatta tccgacttat ctcccataag accttttaaa tcaataaatt gtgttggagt
    25261 catctcgtat ttttcaatta cagaattaaa gttgtattct tcaacttctc caactccttt
    25321 ttttgttata agagtagttg tattatctga agcaagttga atagcatctt tatctccagt
    25381 tactatgtat accttatagc catcatcttc tgctttttta gaaacagttc ctataatatc
    25441 atctgcctca tagccatcta tttctaatct atttatttta aatttatcta aaaggtcttt
    25501 tagtggctgt aattgttctg ccaattcatc tggcattcct tttcttccag ccttatattc
    25561 tttatactct aaatgtctaa atgtaggtgc ttttctgtca aaagctacac ttatatgtgt
    25621 tggtttatat atatctatca ttttaaatag cattgttgta aacccatata tcgcattagt
    25681 ctttaaccct tctttattgt tcatttctgg cagagcataa aaagctctgt ttattattga
    25741 atttccatct attataatta attttttttc caaattatat cactcctaaa aattatctat
    25801 ttttgtaaca tatatattat ataccaatat agtgttattt aatattccca taataataat
    25861 agtatattaa aattaaatat gttgcaaaca atatattttt ttgctataat aatatacatg
    25921 acatgcccga gtggtggaat tggtaaatac aatggattca aaatcaactg tgttgattca
    25981 taagttttta tgatgtttta cagtttgatg agtattttgt attcaatatt cctcttgcat
    26041 attcttggaa aatctggtag gatatacaag tagttcggat ttaaaatata agccgctgtg
    26101 gcggaactgg catacgcata cgactcaaaa tcgtacggga aaccatatgg gttcgagtcc
    26161 catcagcggc accaataaaa aaaactcttt agtatatact aaagagtttt tttattgtaa
    26221 tattctttca tctttatttc tagtcttgta taagtataaa taccatagtc ataacttctt
    26281 gaactcctaa aatatatcta aacaaagtag gattttttat gtattcactt aataaatcca
    26341 tacttcttat catattgatt ttttcccact ctctaaaact tttccttctc taaaaatatt
    26401 tataaccaat catcattatt cagtataatg attctatatt attttaaagt atttgtcatt
    26461 taaaacaaac ttgtgataaa agcatatctg aaagtattct gattctaata cttaataaag
    26521 agttcttttt acagttatag atataaacaa cttctatctt aatagactgt atagaagcac
    26581 aatcaaatgc aaacacatat agttaagtaa tatgtccttg atttttcttt attattttat
    26641 tgtaatagct ttattaattc attataatat tacatcattt aaaaaaaatt atatgaaaag
    26701 tcaaaattta catatagatt aattaaactt gtaaaaacac atataaattc gtacaattaa
    26761 gtacttaaaa cttgaaaata gttactttgc tatatatttt agataaagat ataatttatt
    26821 tggttaagaa aagaagtggt aaatataaaa ataaggagtc taatatgata ttcagtagtt
    26881 taatattttt atttttattc tttccagtta cactcatttg ctattacttg gcaaatccta
    26941 agtataaaaa tgttatgtta cttctagcaa gtattgcctt ctatacatgg ggagaaccaa
    27001 aatatatttt tttgatgata ctatcaataa tagtaaacta tatatttggt attaaagttt
    27061 ctggcagtaa aaataaaaaa atgtgggttg tgctttctgt tatttacaat atatctattc
    27121 ttgctgtatt taagtatagc aattttttta tagataatat taatttttta ttcaatacag
    27181 atataactat acctgaggtt aaattacctt taggtatctc atttttcaca ttccaaataa
    27241 tgagctatgt aatagatgta tatagaaatg atgctaaagt tcaaagaaaa ttagctaatt
    27301 tagcattgta cataagttta ttccctcaac ttgtagcagg tcctattgtt agatatcaga
    27361 ctgttgcaga tagcattgag tatagagaac acaattggga caaatttact caaggtgtaa
    27421 acagatttgt tgttggtctt ggaaaaaaag taattctagc aaatcaatta ggtgtaatag
    27481 cagatggtgt atttaataag tcagctggag atttatcaag atttgaggta tggctaggta
    27541 tagtttgcta tacacttcaa atattctatg actttagtgg ctatagtgat atggccattg
    27601 gtttaggtaa aatgtttgga tttgagtttt tagaaaattt caactatcca tatatctctc
    27661 aaacagtatc tgagttttgg agaagatggc atatatcttt aggtacttgg tttaaagact
    27721 atgtatactt cccattaggt ggaaatagag tctctaaggc aaaactatat agaaatctat
    27781 ttgtagtatg gtttttaacc ggcatgtggc atggaactag ttggactttt attatattgg
    27841 gtctatatta tggaatatta atatcagtag aaaaagcatt cttagaaaag tttctatata
    27901 agatgccaag aattgtaaga cacatatatc tacttcttat agtcatgatt ggatgggtat
    27961 tttttagagt tgatgattta ccagcagcta ttaaatttat aggtattatg tttggtgctg
    28021 gaaattatcc ggttatcagt aatgcattca atgtgtttat aattgaatat tggtatgtaa
    28081 ttgttggggc aatccttcta tcaactccta ttgtaaaagt tttaaaatca ttattaatta
    28141 agaaaaataa aaatacatta aatagcacat tatatcaagt tactaatatg gttttcattg
    28201 tttcttgtat gtttattgta ataataatgt taagtagctc aacttataat ccattcttat
    28261 attttagatt ctaattggga ggtataaaca tgagtaaaaa aaaaccaagg attgttgcca
    28321 tttcattttt aattatagta tttggatttt tcatactaaa cttcacactt ccaaagaaaa
    28381 aattaagtat aactgaaaat agaaatcttg caaaatttcc gactgtagaa aatttaaaaa
    28441 aaggtgactt tatagccaag tttgaagaat attttaatga ccattttgca ttcagagata
    28501 gaatgatatc aataaataca aaggctcaag ctagtttaaa taaaactaag gtaggtaact
    28561 attatctagg aaaagataac tggatattag gtatgtttcc agaaatttta gaccaaaaac
    28621 aattaagtcg atacgaaaag tccattaatt atttatctaa tctaagtaaa gatatgggaa
    28681 aaaatgtgta ttttacaatg atgccacata aaactaatat gttaaaacat ttgtatccta
    28741 aatatgttga taatatggat aatatagaca taaatttaaa gaattttaaa aatagattaa
    28801 atccagattt aattaaatat atagatatgg atgagtattt tttaagtaac tattcagata
    28861 aagaaagaga aaatttatat tttaaaactg accatcattg gactggatat ggagcatttg
    28921 aaggctttaa aatgatggca tcaaatatgg acttaggtct atctaagcaa gatttagaca
    28981 agcattttag tagctataaa aagtctataa ttactgataa gaaatttata ggaagttata
    29041 atcaaaatat agatatgcta attaaagaaa atgaatatgt agtttatatg acaaaagata
    29101 accaagatta tagctttgat ataaatggag aagaaaaaga agaaaaagag gtttatgcaa
    29161 ctgaaagaga taataaagag tgggattatg gtggtgcata cattagagga gctaaaacta
    29221 atatattaac tataaaaaac cctaaagcat tagtgaataa aaaaatacta atatttagag
    29281 attcatatca ggctcctaca acacttttat ttgctgatat gtttaaagaa gtagagatag
    29341 cagaccctag aaatataaac tcaatatata aaacatacaa agagataatc gaggaaagta
    29401 atgcagatat tgtaatgttt atgtataata gttctgggtt tgattcaatg atagattcaa
    29461 tgatagataa aggaataaag tagtaaataa aaagattaaa caaaagtatt atctaactaa
    29521 agatggatgg ctattaggca actttgccaa attattatct gattatcata taaaatctta
    29581 ctccaaagcc attaataact tgagtaagtt aaatagaaaa aaagattttt actttgtttc
    29641 acttcctcat aagacaaata tgcttaagaa cttgtatcca agtggtataa aaggtaaaaa
    29701 taatatagat attaacaaag aaaacttaga aaagcagtta aaagacataa atttcttaga
    29761 tatagatgat tacttttata aaagttttac cgaaaaagaa agagaaaact tctttttaaa
    29821 aacagaccat cacggaaatt cattaggagc atttgaagaa tataagttta ttcttgataa
    29881 attagacctt agcttatcta aatcagaaat agatagtcat ttaaaaagat acagtactcg
    29941 atatgtaaat gactgcgaat gtagttttat ttatgtataa tagctttgga tttgctggaa
    30001 tgatacaaga aatgattgac aagggaatag cataacaatt tgaatcaact cctttttata
    30061 caaaaaatag ttctcaataa ttcctaatct atatgataat ttagtacatc tctttaacaa
    30121 taaaaataaa atcacataaa ttcttatacc atcacttatc tttatgataa attggttgag
    30181 aaaaaatttt ataatttata tgatatgtaa tcttaattaa ttctttactt tttaattctt
    30241 tatctactgc aacctttgat aaaagaaacc atccaagact attaatatga atttatataa
    30301 aaattacttt caaataaagt actgcaatat ttttatttaa agtatctata atctttaacc
    30361 acaaaaagcc acaaaataca atgtatacct atggcttttt ataaatttac ataattgtat
    30421 ataaagatat actctaaaac tgtcttaaga atctaaagtt taaaaataca atatttttat
    30481 tgtgaattta aactttttat tacaactttt tatctaattt attgtataca acaacactac
    30541 aaataaattg aaataaaata agcaatccaa gaacaactaa aacccacttg cttattacca
    30601 ttacagaaaa tacactcaat atagaaacaa taaatataag aattacaaga acataggaca
    30661 tgatttgatt agtgatacgt ccagctttat cacgtaacat aattcttctt tcatcattca
    30721 tctctatcct ttggtttttt atcttttctt cataatctaa tgctctttca ggcttactcc
    30781 aatacatata ttgaagaatc atacatacac ctggacctaa agcagctcca gataatcccc
    30841 aaataaaagc ctcaaatgaa aactcagtaa acgtagccaa taaaacaagt aaaattccac
    30901 aaataaaata tactattcca agatataaca tattcttttt catttttact cctcctcata
    30961 aataaatatt tcttcaatac tcctatcaaa gtatctagct atcttaaagg ctaagatgat
    31021 agaaggatta tacctaccat tttctaatga acctatagtt tgtcttgata cttgcaaaac
    31081 agaagcaagt tcttcttgtt ttatgcctct ttcttttctt atttcttcta atctattttt
    31141 cacatctatc cccctttaat atctcaacta cggaaagtct actttccata attatacaac
    31201 tatattccat ttatgtaaag cttactttcc atatttacaa aaaaataaca gactattttc
    31261 agactgtaat tttagaattt catgttgttt attaatttta atgttattta ttaattccat
    31321 attatttatt aactttaact tggtttctga attggaatcc aaacttctgt agtataatca
    31381 ggagaattga tatcgccatt gggataaagt tcaatatctg gtaaattaga atacacatac
    31441 ccagaacttg gtaaccactc agtaataatt cttttttgca actcctgtat tgccagagca
    31501 tttggcattg gagaaacaca ttcaaatact gcccatgtac ctgatggtat taagtattca
    31561 tgagtatctt ctaatatagg cttatctgtt ggtgcagcaa tataataatc taagccctta
    31621 ctatttgtac acacactaac tccaagcaat ccacaaggtt cgttatttat taactctgaa
    31681 agtttatcaa ttgttccatt ttttatgcat ttagcccata acttaggaac tttctcaaaa
    31741 cactcttcta caatcatgtt catactttct tttataccaa caatacgaaa tcctttcttt
    31801 tctacaatac gatattgcat ttctacattt ccttttacat aaatgcttaa tgtcatctta
    31861 ggatatgctt ttaaaacaac gccttttgct ctagctgcag atggagaaat gttatgtata
    31921 ttttgaaaag ctctattaaa agatgttggt gaatcgtaac catacttctc agatagttct
    31981 aaaattttga tgttactgtt ctgcagttca aatgcagcct tagtcatacg tcttcgtcta
    32041 atatattcag atactggtac ttccgcaata tatgaaaaca ttctttgaaa atgaaaagtt
    32101 gagcaacatg caatttttgc tgcttctgca taatctattc cactttcaag attttcttca
    32161 atataagtaa tagcttgatt taatttattt atccattcca tttaatatta cctccaaaca
    32221 aattatacag tttaataaaa taatatacct ctctattcat gcacaaaatt gtaagcattt
    32281 aaattcataa gcattttcta atccatcaat acaataaatg taaaaattat attatacaat
    32341 aaaaaagttc aataacatta tataatatta ttgaacttct tataaaaatt aatttaagtg
    32401 tagttaaatt aagtattaca ctatcttata tattacaata tccaactatc ttgtagtctt
    32461 ctggcacttt ataatcttta tctggagtac ctaaattcca ttttaactca aacatagttg
    32521 cacttattat tgttgcaaaa taaagcataa ctataccaat atctattttt tcttcatata
    32581 aattagtatg gccatctttt ctaacagcta aaattacagt gcctccatca actataaatc
    32641 tccatggttg tctatttaat gtagatggag ctaatcttgc ataatgaaat gcatcaagaa
    32701 gtgctctttc ttctaaaact tctatgcttg caacatttcc ccattcgttc atataaacaa
    32761 catcttctac acctagtcta gaagaaccct tatctgttac aacttgcata tcagattttg
    32821 aataattttg cccagttttt gtagcattta acactttagc attatttaca ttttctccat
    32881 atccaatagc tataattcct gttacctctt tatctgaatc aattccaagt ttttctttta
    32941 ctttttttcc atcttcaaaa gtaacccaac aagaaccaat tcctagttct gttactttaa
    33001 agattatatt ttctcctatg taccccgaat tttcaatata attatctttt acatcagata
    33061 atattataat ataacttgga gaatctatca tatttccttt gtatcctgct actttttcta
    33121 aattattaaa gacttcactt ctattcataa ttcttatatc aacatctatt tctggaacta
    33181 gtttcttaca agattctgag tatttcttaa tttcactaag atattcctct ttaatatctg
    33241 tgttcttata ttctctaaca gactttctat ttaatataat tgttttataa tccataattt
    33301 tatcctcccc aatctagtct tgttttaatt atatacccat taatatatta ttttactcat
    33361 ttatttaata aataatgatt acaattttgt aattattatt tatcaataac attccacttt
    33421 tacattaata atgaccagtt gtgtaaaatc cattgccaac caccaaataa aaacatatta
    33481 taaaggtaat ataaaataac aaacaaatct taacaaaaaa ttaaactttt tttacacgaa
    33541 agaaggcttc ccgttgcctt ctttattttt ataaaaaaat aagctgtttc taaaatgatt
    33601 tcacattttt gaaacagcca agttattcta taatgacaac tataatttga ggatgtgagg
    33661 gagagttgtc attataaatt tagggtaatt atattatgtt ttaagctagt tctttctata
    33721 tttatataat acattttata tatgaatttt atatgagatt ggtataaatg atatatgaaa
    33781 ttacatatga ttacattata ttaaatttta ttattacatt ttccacaaca atactcatat
    33841 gtctccacat tattcggaat atttacaaac acaaattctt tacagttctc acaatacttt
    33901 aatatagata tagttccaca agtgtaacat tcaaatatta cacaatcctc atgttcctct
    33961 actatttcaa actttttact atgttcacca cactctgggc acttgtgatt atttacattc
    34021 ataaatactc ctccttattg gtatagttac atgtcaaaaa cttaattaat gtattctata
    34081 ttacttatta tatattctat aataaatcat attctaatat aataaaacaa attaaataaa
    34141 aaaaaaccat aaattttaaa tttatggatt aattcttgta atgataactc tatttgagga
    34201 tgtgagggag ggttatcatt acaatagggt attatattat ggtttttaag ctagtctttc
    34261 tacacttcat ataatacata tgctatatga attttatatg atttttacat aaatatttta
    34321 tgaaatttaa attttttagt cattttgaaa tttgtaaaaa gttctctaaa aatccacagc
    34381 ataataaata gccaaaattt aagtaaaaca tcataaaaaa atttgtccaa taattttaac
    34441 aagtcacctc acctcattat aattattgac acaaacttaa ataaacaatc tataaacctt
    34501 ctacaaaatt taaattttcc tcttattgat acacaatctc tagtttgtca attttatttt
    34561 gcatctctaa gaaaatttct tcaacagaat tgttaaatat attgcctaaa tagactcttt
    34621 tatctttttg aaatgaataa gattttacat taccattaga agaaatatat aaatgactcc
    34681 actctgctcc atattttgaa aatctctcct ttgtatcttt aaacctcata tcttctattt
    34741 ttattgcttt ttctctgtct cttcttacta cagtatgacc cctttttatt aaactagtta
    34801 tttttatatc ttcttttaat tttatacgtg tatcatcatt tcttgaatat actttccata
    34861 tcactttatg acgataatta tctaattcct ttattaaact tctatcaata gtaaagctat
    34921 ctttagttac cacaattaaa tcaaaatggt ctaacatata ttgaaataca tctctcatac
    34981 ctttattttt taaaatatcc tcaccaataa cctctataaa tctacagcct ttctcataca
    35041 tacactttaa taaacttgtg atttcagaaa aataattatt tgtattatta tctgcatcta
    35101 tttctagagt aaagtacaaa ggagtaatgt atgatttgtt tcctgttatc tcaaatacac
    35161 ttgatactgt ttgtatatta tcttcaaagg ttaagtatac attctcataa aacataaaaa
    35221 attccataac tttttctctc atattaggga tattcctata tctattggat aatatattta
    35281 ttatgtcgtc agtagtattt ttcccatcac attcagccag tacaacaatt tgcttccaac
    35341 ttaagatatc cacatttccg atactttttt tatatccatc ttcttcatca taaataggac
    35401 caattataat gttttctttt ggccacagat gaaccctagt tccatctttt aatttcggat
    35461 atttatttct tacagactca taaaatctac ttgtatcacc cattattctt tactaccccc
    35521 catattttaa atattctatg ctaaaaatag cactttattt ttattaattc aacaattatt
    35581 caaaattggt tattaaatat gtttaaatgg atttaacatc aaccttattt atatgttatt
    35641 gatgttcata tatgttatat aaaagcttat ttcttagact tcaatgtaat tttaactatt
    35701 tctggcttac aattaagcct aattaaaact tttgagcccc ctaagccttt atttaaaatc
    35761 atagtgctat tatctttttc atatctgccc caatcatact taggaaaaaa ctctctattt
    35821 ggagataaca cacctccaac aaaaggcatt cttattatac ctccatgaac atgtcctgct
    35881 aaaaccaaat ctgctcccca ttttgcatat ttttcaaaga aaaatggcgt atgtgctaga
    35941 agaatattat actcattttc atttacttta cctagattac tttctacaaa attgtcactt
    36001 agttctaact ttttattatt agcaaaaaaa tatggataac attccaatgg gacaattaaa
    36061 ccatataaat taagatgact attcccttta tatattctta cagattcatt ttccagattt
    36121 attattttct ttgaatatag ttccttaaaa taatctttat atagatgttt atattttttt
    36181 attaaagatt tttgttcatg atttccaatt atatggtata cttcatattt ttcaaccaaa
    36241 ttatctatta aatctaatgc aacttgaaaa tttttatttt ctccatctac taaatctcct
    36301 gttataaata taacatctgg atttaatgat ttaattttat ccatcaacac cttattgttt
    36361 ttatcaaata ccttattatg taaatcgctc acttgaacta ttttaaagtt atcaaattcc
    36421 actggaattt ttttgttgaa aatagtatat tctgtcgttt ctatatgctg agtttcgtac
    36481 ttatacagaa tatacaataa tattaatact agtactgtca ttgaaacctt tataatcata
    36541 ttctcttcct ctttattcta ttttattaat attattataa tgcttttatg ttttttttaa
    36601 aacaataaca tcatcacata catataaatc ttttcgacat tataaaaata agttatcctt
    36661 ttctaaaatt ttcatttatt ttagaaaaga ataactataa aattatctat aaacctctat
    36721 attgtgaaat atagtttttc ctttatttaa atttttatat atatgctcta aagttccatc
    36781 aaacctaata gaatgcccag actctaaaat ataagttttc ccatccacat taaggtcaag
    36841 tttaccttct attactagca catactcttc caaaacatga ctatgtgtag atgaaacatg
    36901 agtacagttt tcttcaagct caattataaa aagttcaaac cttctttgag ggctaaaagg
    36961 gtatattgga tatagtttca tattcccttg ttgctcaaca ataggctcta cttcttcttt
    37021 ttttataacc tcataagtat ttgtattttc atttaatagt gtagtaaaat ttattttaaa
    37081 tccagatgaa attttccata aggtggatac tgttggactt gattcacctc tctcaatctg
    37141 tccaagcatt gctttactga cacctgtcat ctttgaagct ttatctaaac ttatgcccat
    37201 ttcttgtctc aataatctta aattttctcc cacattagga aatttattat ccatgttaaa
    37261 atcctcctga tagctatttg tattctatga tttttacccc tgtaagttct actatctctt
    37321 ttaattttaa catatgattg ttacaaattt catcaaattc atatatataa tcttcaagtc
    37381 ctaatgcctt atatttatcg attccaaatt tatgatatgg aagtaattcc atctttcctt
    37441 ctggaacatt ctgcttcaca aataatgcag tatttcttat gttttcttca ctatcattta
    37501 ctccataaat aattggcact cttataacca tagatttatt caattttgaa agtctacata
    37561 tattatctaa tataatttta ttacttactc ctgtatattc tttatgaata ttatcatcca
    37621 tggattttat atctacaaat atgtggtcta ttttatcaaa tacatcattt accttattcc
    37681 aatcaaaata tccacaagtt tcaattgcaa tatttatgcc tttattataa aaaatatcaa
    37741 ctaattctct taaaaaatca atctgaagtg taggctcacc tccagaaaaa gttatccctc
    37801 cattagattc aaagaaaaat ataaaatctt tttcaacttc ctttactatt tcttcaacac
    37861 tcatttcttc ggtcattata caaatagcat ctttaagaca tgctttgata cactctccac
    37921 ataaatcaca tttattattt atttgtgttc tatcaaacag tgaacttata ttttgaggac
    37981 aaacatctac acatctatta caagatatac atttatcttt cataacacct aatttcacta
    38041 tattactcca tgaatctgga ttggaacacc acttacattt taatttacat ccttctaaaa
    38101 atatagtagt ccttattcca tctccatcat ttactgaaaa atgttgcact tttacaactc
    38161 tacctttttt actcataatc tacctcataa ttaaaaatta ctatgtgaat ttctagctat
    38221 tatagcatct tgcatttctc ttgataaatt aacaaattga gtactatatc cagcaactct
    38281 cactaataaa tctttatatt cttctggatt ttcttgagct tttaatagag tatcatttga
    38341 tatcgtatta aattgtacat gaaatcctcc taaggcaaaa tatgatttaa ccatagatgt
    38401 tagatttcta agtcctcttt ctgtttccac caagtcttga ttcagtctta aatttagaag
    38461 tgttccacca gtatgaacat catgatttat ttttgatgca gatttcatag ctgctagtgg
    38521 acttgttgta tcagtaccaa caaatggaga aactccctct gtcaaaggtt ttgttgcttt
    38581 tcttccgcaa ggagttgcac ctacgatttt tccagttggt acatagtttg atatacccat
    38641 aaatgcacta ttaaatttag aaccaaaaat atccttgtat tttctagttt cagtataata
    38701 aaaatcagaa acttcaattg ctaatgaatc tacataatca ttatcatttc catacttagg
    38761 aacatctaac gcaagttttc ttaactcttc ataaccttcc caatcattat ttagtgcttt
    38821 ggttaattct tccaatgtag taaccttatc ttcaaatact aattttttta tagctgccaa
    38881 tgaatttgaa actacaccta atcctatacc agttaataca ggtcctatat tatattttgc
    38941 tcctcctttg cttaaatcga cccccttatc taaacatcca tctacacaag tagataaaaa
    39001 tggtcttggt accatttctt tatgaatttg ttgagcaaca gtagttccta taacagaatt
    39061 ttttacaaga tatgctaatt gatttaaaaa ctcatcctta agttcttcaa aagaagtaaa
    39121 ttctgtgata ttttttgtat ctagacccat tttttctcca gttaacctac tcttaccttc
    39181 attcatagca tattctaaag ctgctgcaaa attgatattt acggctgaag tccactgtcc
    39241 tgtttttcta aaatgaggaa ctacacatcc acagttactc caatctctag cgtcttctgc
    39301 atcatatcca tcttgtagta acatttgtgc ccctgcatta tcgctgtgta tagcagggaa
    39361 gccagttcct tgttttacta atttagcaac tgccatgaca aaattatctg gtgctccttg
    39421 actcacccta acacttaatc ctggctggtg agtttttaca ctttctgtag cctttaaaca
    39481 catatatgag atatcattcg tcccatcagt accatttctc tttttaccac caacagtaag
    39541 attttgaaat tgattatatc ctgcaaaata atttgccgta tttgctgata tagtccatac
    39601 ccattctgat aacttaatcc aaagtgcttc tatcaattct tgagcttctg attcagttat
    39661 tttgccttct ctagcgtcgt tttcataata cggatacata tattgatcaa atctacctaa
    39721 atttaatgcc aatggatttt ctgatagaat accacctagt tgaacaaacc atacaaattg
    39781 tattgcttca taaaaattag ttggagggtt tgctggtaca ttcatacata tctctgaaat
    39841 ttttataagt tctaactttc tctttttgtc tgtttcttgt tcactcatct cttttgcaag
    39901 atttgaatat ctttgtgcca atgtcataat accctgtgca actatagaaa cagacttata
    39961 aaagtctatt ttttcaatat tttctgaaat cgatatatct aattctttaa tttttttatc
    40021 tgcatcttcc ttaatccctt tatatccttt tacaaacagt atatcttgat aatctggtgt
    40081 tacctcacca actgcctgtc tccacttaga atcattatct attattcctg tatctactaa
    40141 taccttagct gtatcttctg ggattcttgc taaaaaaact tcttccaaag attttccctt
    40201 ccaatatgga aatatttctt ttcttataaa ttctatttgt tcttttgata ttacatatgg
    40261 gtcttgagtt ctttcatcaa aagtatccat ttctttgtct acccattgcc aagaaaactc
    40321 tggtgttaat atccctgttc ttctaaattt tcctgctgta cctactatta attcattttc
    40381 aaagattttt ataggaagct ctttacatgt ctccaaaaaa gctttagctc ttcttataca
    40441 gatagcttct ccctcagttt ttttatgtga ttcagtaaaa atcctagctc tttcacaaca
    40501 tatcataggt ttagaattaa tatattcttg tctaaatgct tctattctat tagtttgact
    40561 catttaaaat ccccctttgg ataaatatat acttatatct ttgtatgtta taacatactt
    40621 taattatatt atactgtcct ttagcataaa atggaagcaa aataatttat tttttcatct
    40681 accttgaaca cctatatatt aatacttttt ttgctaaatt tgtaaaatct aaaaaatttg
    40741 tctatgatat attttttata ttgttatagt tatttctagt atactaacga tttgaaatat
    40801 caaatttata taataggctt agttttaaaa ctttagttga ttgtttaatt ttgttaactt
    40861 caacatgtat atctttcata taaggaagct ctacaacacc tactccctta ttaaagtctt
    40921 cttcaaccat agaaaaaatt tctttctcag ttaagttcgt attagtcaat gacttaaata
    40981 aattatatat aaatttaata tatttatcac tctcagataa cttctcatct tctggatact
    41041 ctttagcaca gagaatatct attgttactt ttccttcttt atcatcttca gatacagaat
    41101 agaataaact tctaatattt tcttcaggtg gtttttcaac actatttata gacactacaa
    41161 agctaccatc tgattttgaa ttagtaatac tataaccact gtctattatg gctttcgaaa
    41221 atctttgaga taaatctttt tttacttctt ctctaccttt cacatcattc atcttttgcg
    41281 agtaattatt aaataactca atagattcat cttttttatc ttcaactgat tcttttaatg
    41341 aatctttact aatttgtttt gaactactta agttcttatc agatacagga gacttacatc
    41401 ctaccatcaa tgctaaacta agatttaaag ccacaactat tgccacttta tttatatttc
    41461 tctttacttt catacacaat cctcccatca gactaacctc tctaaaacat tattcattgt
    41521 attagaatat gtttatattc tctttatatt aaaaatttat tactcaacac atatcacctt
    41581 cctatctaat tcttatagat tactattagt aaaattataa attccttaat acaaaaataa
    41641 ggatgttatc ttttgttatt aaaagataac atccttgttt ttttgtatca atacatatgt
    41701 cccaactagt aacttaatcg ctccaactgt cagtatcttg gtccaatggt atgtatatat
    41761 ttagtataaa tttatccata ctattttcaa atgataattc tccattatat ttttgtaaag
    41821 aagatttaat actttgaata cctattccgt gcacaaactt atccattttg tttgttaaca
    41881 atatattttt attgaaagta atcttattta gtttactatt ttcacattta agtacaaaaa
    41941 atgactttgt tatagttcct ttaattctaa tatatttatt aatattttca tccaatattt
    42001 tatcacatgc ttctattgca ttatccaaaa cattagagaa tatacttgaa acatctatag
    42061 gttttacaaa atttactttt gaaaaattta tagagcaaat aaatttaatt ccctttttta
    42121 aacatatttc actcttttca ttgattataa tgtctaatat catatttcct gtattataaa
    42181 tatatttaaa tgcttttatt tcatctttta aactgttaac atattcgtca atttctttgc
    42241 tattatttct aagcttgtct atacaataaa tgtgattatt tatatcatga tatagtttct
    42301 taactcgcat atgagattct tgaatactta aataatgtgc atattgcata tctaacttat
    42361 tttttattaa ttcagcttga gattttaatc tattttcttt tattatttct ttaaacaata
    42421 gtataagaaa tatactacta gctcctacca atttgggatt cacaaaatta tcaaaatagt
    42481 atccttctga atgtaatgac ccaaaccgtt ctaatttttt taatacataa tttacaagca
    42541 tattcattgt attagctaat aaggcaaata ataaatatac ataatttctc ttatcttgac
    42601 taattaattt tatagacttc ctaaaaaagc taaatataag atatataaga ataattatta
    42661 aattactata tatctgaatt tttatagatt ctaagtgagg tattaataag gattctttag
    42721 atgaaataac attacctgta attgcaaaaa atagtattct atatataaca gcatccaaac
    42781 attcataata tacactaaat agataaaaga aaacagaata cttaatataa cctatcttat
    42841 aaaaataatt atagtatcct ccccaagcaa taaatgctaa tatataaaat aaatagttta
    42901 tattactaaa gtaatttcct ccattaaata atctacttat ctgaactata atgtaaataa
    42961 gaaacaaaac aatataaaat actatttttt catttttttt actatccttt ttataaatta
    43021 aaattccgtt cattatagaa aactgtataa atatagataa aactactaat agctcagtca
    43081 taaaatttag catattgtat caccaagaaa ttttaaaaat ttctccttaa cttctttata
    43141 tctatatcta ctaataggta cctcttctcc actttccaat atcacagtat taggctttat
    43201 attttcaaca tatcttaaat ttactataaa acttttatgg catcttataa atttatatgg
    43261 atttaattct ttttctattt tacttaaact atattttata tcaaaattct tatttattgt
    43321 gtgtattagc atatcttttt tttgaacttc tatatatttt atttcattta aataaatctt
    43381 atatgtatta gacttatttt ttattgtaat atgacttttc ttatttattt caatatcttt
    43441 gatacaagtt aacacatgtt tttttagatc ttctagctct attggcttta gtaaatacct
    43501 ataagctctt acctcatatc cttcttgcac ataatctatt aatgaagtta taaatattat
    43561 ttccatttca ttatctactt ctctaatctt tcttgcagta tccattccat ttagtttttc
    43621 catttttata tcaagaagta atatatctat atcttttaaa ttactttcca atagatcttc
    43681 tccagataga tacttttgta tctcatattc tatatttata tcttctaata tattctcaag
    43741 gtaatcttct attaaaagtt gtgtttcttt ttcatcttca caaactgcta tcttaatcat
    43801 aaaatgcctc cttacataat ttctagttaa tacaattaaa atttttataa tatatttaaa
    43861 gataattttg tatatctgat actttaggat aacattttca aattattttt atcaatactc
    43921 aatcctatac aactgttatt ttgatatctc aatttaaaga cagaaattac tataattaaa
    43981 aacagtactt actgataaaa gaagatgtct taaaatatca aaaaaataat tttaggacac
    44041 cttcttttat ttaaactttt taagccttaa ataatacatt aatctcctat ataattgtac
    44101 tgcatataaa atcaacaata taatctgtag tacaatagca gttacagatg ctccacaacc
    44161 actatataaa tttcttattt caatattcaa taaatatata aatattacta ctaacataaa
    44221 gaatataaac atattcataa ataaaattga ctttacttta ttttttttat cagaatcact
    44281 atataattta ggaggtatgt ctttgtattc tttcgaccat atataccatg cagatgtacc
    44341 cataaaactg ccaatactcc taaacacaag attccagcca tttgatttat gttcatcaaa
    44401 ataattattc tctgcatcat agtagtaatc aacagtgtat tttatttttc ttggactttc
    44461 cttatgaaaa taaaatattc ctccaaattt atttatccta tataaattat atcctttagc
    44521 ttcaatatct tctaaccatt tctctatctt atcaggtgaa ctataccagt caaatttgaa
    44581 ttttattttc ttttccataa cactcattct ccaaaatgat atttttaaat agcttaaaaa
    44641 tctatttaaa taattatatc attttgatac taattttagg ttacaatcag atatttaaaa
    44701 agctatttaa atagtaataa actaatggcc ataacgccca ttcctgcaat caatccataa
    44761 atggataaat gatgttcccc gtactctcta gctgatggta ataattcatc tagtgatatg
    44821 aataccataa ttcctcctac aattgcaaat acaattccca gagttatatc attcaaaaaa
    44881 tttctaagaa gtacatatcc aatgatcgct cctaaaggct cagacatacc agataaaaag
    44941 gaataataaa aagctttctt tttatctcct gtggcataat aaactggtac agatacagat
    45001 ataccttctg gtatattgtg tattgcaatt gcaattgcta tcggtatagc tattgtaaca
    45061 tcatcaagag ctgatataaa tgtagctaat ccttcaggaa aattgtgaat tgctatagcc
    45121 attgctgtaa atacacctgt tctcaaaaga gacttatttt ttttgatatt cttttcttct
    45181 atattctcca ttttctttat ttcatgtgga ttttcttctt gtggaattag cttatcaata
    45241 acagcaatga tagccatacc tataaaaaaa gctattacag ttgaccaacc tcccaatttt
    45301 tctcccatag attttgtcaa agcatcttgt gctttaggaa aaatttctat catagaaaca
    45361 taaatcataa caccagcaga aaatcctaag cttatagaaa gaaacttcgt atttgttttt
    45421 ttagcaaaaa atgctataca acttcctata ccagtagata aaccagccaa taatgttatc
    45481 aaaaatgcaa atattacatt attcaaataa atcaccttct ttttaattga tattgattat
    45541 catttcattt atgctatcat atatatttta tatagtcaat atttatcaaa aatatacaca
    45601 ataaaaaagc agagatataa ccttagtctc tgctttttct tcatagtata ttaaaattat
    45661 ttattcaaga aatccactgc atattgcaca tataaagcag ttccaatttc tagggcatct
    45721 tcatctatat taaaacatcc atgatgatga ggataacaag caccttttga ttcatttcta
    45781 gctcctacaa atgctagtgc accaggagct atattcataa actcagctaa atcttctgct
    45841 cctgttactt tttcaaatag tgttatacag tcttctccaa atagcttaat tgctgcttct
    45901 gtagctatct ttgaacattc tttgtcattt ataactgctg gtgttaaata accatattct
    45961 aattcagctt ctgctctata tgctcctgct gtagattttg ctatacgttc taaaattcca
    46021 ggaattttct ttctaagctc tggattaaat agtcttattg taccttctaa gacagcttca
    46081 ctcgcaatta cgttaaatct agttccagaa tttaaaactc caacactcac aaccaatggt
    46141 tccagaggac ttacttctct actaaccata gattgcaaat tcataactat tgctgaactt
    46201 gcaagcactg catcaactcc ttgatgagga agtgaaccat gaccacctct accttttaca
    46261 gtaattttaa agaaatcagc agaagccatt cttggtcctt cttctactga tatagttcca
    46321 gattctacat cagtccaaag atgtattcca aacacactat ctacaccttc catagcacca
    46381 tcttgaatca tagctcttgc acctttgcca acttcttctc ctggctgaaa aaataatttt
    46441 acagttccat tgatactatc tttaatatca tttaacactt ttgctgcccc tagaagcatt
    46501 gatgtgtgac catcatgacc acaagcatgc ataagtcctt catttttaga tttgtattct
    46561 acttcagtac attctacaac ttgtaaggca tccatatcac ctctaagtgc tacagtcttt
    46621 cctgaattag ccccttttat cgttgcaatt acacctgtac ctccagctga tacatatggt
    46681 attcccattt tatcaagttc ttctttaacc ctctttgatg ttctaacttc ttccatactt
    46741 ttctcaggat tttcatgaaa ttcccttcta agcttaatta catagtcttt ataactcttt
    46801 gttatttctt taatatccat tacagacctc caagtagtac acattcttct tatttaaaat
    46861 attttttatt agttaaatac tatattagat ttacaaagat acccgctatt actacagaag
    46921 ctattgtaac tgtagtaaat ccaccaacaa gcatctttgg aagcatttta tccattaaaa
    46981 attctttttc ttctggtgtt tcagccagag cctttactgc ttcttcagtt aatatatagt
    47041 ttggcggaaa accgtaaagt gatgtaagtg aaactgaaaa agccatttct ttgctttcac
    47101 ctaaaagctt tcctgctata atagaaaaaa ttcccatacc tattacacca aatattatga
    47161 ttcctacaag aggaactgcc atttcaacaa gcattgctgg tgtagctttt gctaaccctg
    47221 caaatataaa agccatcaat gatgtcatta accatccaaa tgaaccagat ttattaagtg
    47281 gttttctatc aactattcca agttctgatg ctattacacc aaatattaaa cacataacat
    47341 atcttgatac aacttcattt gtaagatttg taaattgtac tgctaaccat gctacaaacc
    47401 ctaatctaag tattatcata tatgtcgtat catatttttc tggtaagtct ggaattatct
    47461 taaatctgct tttttgttca ggtaaatcct taactttttc ttcagctgta tttacagtta
    47521 cttttccact tctaaaatcc gataaaagtc tttttccttc ttttttaagc attaatgctg
    47581 taataggata acctgcaaat ccttgtgcaa catacattaa aattgcaagt actgacaaac
    47641 ttgcaagacc ttttgcagta gcagcatctg ccatcattat agatgcaact agccctccag
    47701 taagaggagg tgtagctatt actgctgtat cccatccaaa tactactgtc cccaatgcca
    47761 aagcacctac acatattcct actattcctg ccaaggctat tacgattgtt ttccattgac
    47821 ctgctaattc cttaatactc atcatagttc ccatatgagt tattaacaaa agcataccta
    47881 attgagctag tggtgttccc aaagcggcta agtccacaat attttctggg aaaaaagtcc
    47941 aaaatcctac tataaatata attgctgata caaaaaccga cggaacaaaa gctttagttt
    48001 ttgctgaaac tacatctcct atcgtcagag atattaaaac taaacaaaaa gctgttattg
    48061 cctccataca aaatcccccc tcataataaa tgtattttta taaaatgtat gtatagttat
    48121 ccattatttt actacttttg aaaaacattt caagtcaaat ttcgtttttt ttcataaaat
    48181 tctataaatt ctacaaatta aagttagttt tctaaattat tctttttata aaaacgttat
    48241 ccctcggatt ggctatttta ctctattttt acaaggagaa ttaagtgtaa ttttcaaaaa
    48301 ataaaacata gaacatattt tattcataaa accttccatt aatataaaat gaattgtttt
    48361 tatgaatctt aatatatcct atgtttgtaa gtttaatgcg tatgttagct atagtgtaaa
    48421 acttatatac tagttattgt gtaacctact atatactcca tttttgttta ctaactcttc
    48481 atgagtacct ctttcttcaa ttcctttatc tgtcaatact atgatttcgt cagcattttt
    48541 tatagtagtc aatctatgtg caacaactaa atttgttcta tctttactta attcttctaa
    48601 agactcttga atttctcttt ctgtgacatt atctaaagca gatgtagcct catccaatat
    48661 tattattgga ggattcttta aaaagattct tgaaattgaa attctttgtt tttgtccacc
    48721 cgataatttt actcctcttt ctcctatata agtatcatat ccttctggta aagtctctac
    48781 aaagtcatgt atcctagctt ttttagcagc agctatcatt tcttcatcag ttgcattagg
    48841 gttcccacaa agaatattat ctcttatagt tcctgtaaat aaaaatacat cctgttgaac
    48901 tatacctata ttttttctca atgattttaa actgacatct cttatactct ttccatctat
    48961 ttttatatca cccttatcaa attcataaaa tcttggcaac aaattacaca atgtagtctt
    49021 tcctcctcca gaaggtccaa ctaatgctat agtcttacca gcttttatag ataagctcaa
    49081 attatctaaa acttgagtct tatcttcata tgtgaaagat atattttcta tctcaatatc
    49141 accttttaca ttttcaagtt caatagggtt tttagcttct ttttgatggt cttgttccat
    49201 tatctctata aatcttttaa aacctgtcat accattttga tattgctctg taaagtttat
    49261 taattttttc ataggttgta taaacatttt tacatatagt atataagcag caaaatcacc
    49321 caaagtaatt tttcctatat aagtaaagta accacctgct attacaacta cccactctaa
    49381 gatatccatg tacaaattca taccagagta gtattctgcc attactttat aagaatcttg
    49441 tcttgctctt ctaaataatt tattgcttct tacaaactta tttaactctt ctttctcagt
    49501 acaaaaagac ttagttactt tcatacctgc tatactattt tctaaagtag catttacatc
    49561 acctatagtg actctactct tcataaaagc aatattcatc ttatcttttt tagctattgc
    49621 aaaccaaatt ataaatggta atatagcaaa tattataagc gtaagaggaa tatttatatc
    49681 tataagtata aagaatgaac caaccaacat tactatagag atgaataaat cttcaggtcc
    49741 atgatgtgca agttctgtta tatccattaa gtcatttact attctagaca tagttactcc
    49801 agatttgtta ttatcaaaat acgtatttgg aagtctttgt aagtgtgtaa atacttcatt
    49861 tctcatatca gcttgcatat ctacaccaat aacatgtccc caatactgca taaaatagtt
    49921 aagccctgct tttgctataa atataagtat aagtgctact gcaaaaacca ctaacattct
    49981 taagttttta tttggaacaa cgtcatccat tatatttcta gttatcatag gataaactaa
    50041 atcacataag gaaaataaaa aagctgctat aaggtctagt gtaaaaattt tcttatatgg
    50101 cttataatat ttgacaaatt gttttatcat aagtattaaa tccctccttt attagtactt
    50161 ctaaaaaata cccataaatt agtataacat aacaataact ttaaatcttt tataaactta
    50221 taaatgaaaa caatattttt cataaaattg aatatttatc atatagttgt atgcttgaaa
    50281 taacataaaa agagctatat ctctataaat aaaaatttat aaagatacaa ctctatattt
    50341 aatactgaac tttttttata aatacaaaac tacttcaatg cattcaatat ttttttatcc
    50401 aatgccgttg tatttatacc tgttatatat cctgttgcct ttattgtagg tatatcataa
    50461 gttgttggta gtatagtagt agatacgatt aaatcagcac cttcttgttt tgttgaacat
    50521 tcagcaattt tacattgctc aatttctgct tgtatattat tttctttaac caacctttct
    50581 actctgtcac aaactattgt tgatgttgcg attcctgccc cacatgctac taatattttt
    50641 ttcatatatt gtcctcctac actttcttca atattttata atttaaaata caactgataa
    50701 atttcctata tctttatcta tataaataat tatatcattt tatatcaaaa gaacatctta
    50761 aaattattct tttagtatgt tttttatttc aacattgctt atacttaaaa tatcattttt
    50821 tatacaagac tctatgtact ttgatatatt tttatagtca tttaaatcaa actgttttat
    50881 attcaagtta tattttatat cactaacaat acctaccaaa tcagacttat tagaaaaaat
    50941 atcctcatat ttatcttttc tagttacttc caatctttta aatctatagt ttttatatcc
    51001 ttctatgata attaagtcca tatcttcgta taattgaatc attttatata atggactctt
    51061 atcttttagt tcttcaatat atgctactcg tttatctgat attatacaga cttttctcgc
    51121 cccagatttt ctatgtttgt aagtatcttt tccttcctca tccatatcaa aatcgtggca
    51181 agtatgttta ataactccta cacgataccc ttttttattt aattctttta ttataccttc
    51241 aatcaatgta gttttaccta ctcctgaata ggagacaact gacaatatat tatacataaa
    51301 attgtgtcct ttcataaaac tatctaataa caatatcgac taattgattt tcttttattg
    51361 tttcattctt tttaatctta atcatacaat tacttcttag agttgcagat aatctagctt
    51421 ttgcatcttt cttatcattt aactctacat acaatttccc ttcacttgta tatagttttc
    51481 catttacaaa tctatcttta tttgaaagtt tattaaattc tcctttaaat atagctttta
    51541 tataatgtat tcccttctta tatgttaaat actcaataac aggaactacc acattatcaa
    51601 atacaatgat tgctgcatgt ggattaccag aaagaccaaa caatagcttt tctcccaatg
    51661 tagctacata acaagctcca ccaggcttaa tgtttatctt ccaaaataat tctgttgccc
    51721 ctattttttt gaatacatct ggaattaaat ctttatctcc aacagagaca ccacctgttg
    51781 taattaaaaa atctgcattc tgtaacatat cccttacctt tttttctaac tccaatatat
    51841 catcagaaca attgcatatt gtatctgctt gtattccaag ttttaataat cttgaatata
    51901 aggtatatct attactatcg tatatcttac cattctctaa agtctcattt atatcttgta
    51961 gttctgtgcc tgtattcaaa attccaactt ttaaatcatc ataaacagtt actttggata
    52021 ttccaagact tgctaatact ccaataccat catatcctat attctggttt ttattaataa
    52081 tcaattgccc cttttttata tcctcaccct taaatatata attatcgtat tcctttaatt
    52141 ttacatttaa agttatcata tcacctataa ccgttacatc ttcttttttt attacacagt
    52201 ttgcacccct tggtattttt ccaccagtca ttatcttcac tgcttcacct ttatttaata
    52261 ccctgttaaa tacttctcct gcatacaaag tccctataac ctttaaattt ctattttcag
    52321 aatttgcatt atatgcataa ccatcatatg gtgacctatc aaatggagga ctatcaattg
    52381 ttgaatatat atcttctgca accactttat ttactgcatc tatgagattt actctcttga
    52441 ccctgtttat tggtaaaaca tttttttcaa taatttttat ggcatcttct aattctatca
    52501 ttttaaatac tccccaatat attttttatt taagatattt ctatgttaat atattatata
    52561 ttacaaaatt tggaaatact tttatcttat ctttaattat aactaatagt tatctataag
    52621 tgcagttcaa attttataaa tctaataaaa aaactgttcc cagctagaaa tttccttcta
    52681 tcttgaaaca gaatcgtatg ctttagaata ttttattcta ataaagttcc ttttattatt
    52741 ttcacaattt tatcactttc aatagttttt atagatttta ttttgttatc cacaatactt
    52801 attgtaagta cctctttttt taatattttg ttatcttctt tcaatctata gctcttaact
    52861 actttactac cttcatgatt atatgctgtt aaatcataat tcgcatctcc tacaatttca
    52921 gttattctag actcttcaac accaacatac tctcccaggt caatacgtct aaaattttct
    52981 agtgatacag ccgatttttc atggtcactt ttttcaatca caatactaga ttcagcatca
    53041 acaactgcaa taccttgtga tgagaaagaa ttagtttcaa cattgacaac tttatttccg
    53101 ttaatatcaa catataaagc acttccatct agttcgtcat ttccagtata ttttggataa
    53161 actaatgtca tataacttga tgtatttata tcttgcattg tatttgattc ttttaaaact
    53221 ttaggtttta tataataaaa tgtattataa ggtataccca tattctttat aatatactta
    53281 taatctttat tcataatttc attaacatca ttttgaactt ttgtcatagt tttttgctgt
    53341 gttgctttac ttgctacttg atttttctct ttagtatttt ctttatgaca tccaacaagt
    53401 ataataccta aaatagttac acaaactaat gaccttttta acttcataaa tcaatcctcc
    53461 tttcttaaat tttatagtat ttatctatat atcaatttac agttatctct tttttcaata
    53521 attatattta ttatattata aaataattat ataatattta tttgaattta ataagattaa
    53581 gaagctaatt gtaatttttc tgtaataaaa catactttaa agttgaattt tgaaaattca
    53641 atttacgata tttttattat taagtacctt acaacattat accaaattat tcctaaacaa
    53701 tcaaaaactc catgaatatt taaaggtttt ctattttaaa aatcaccttt gactattaat
    53761 ttatcaaata tgttataata gttttagata atttaaggag gattaaataa tggattttaa
    53821 acaacttgaa gtatttgttg ctgttgcaaa acatcagagt ttttcaaagg ctgcaagaga
    53881 acttttttta actcaaccta ctgtaagtgc acacatacag aatttagaaa gagagttgga
    53941 aactgttctt ataaatagaa gcaacaaagt tattacactc acaaaatctg gtgaaattct
    54001 ttatgaacat gctatatata tattaaataa ttgtaaacgt gcaatttatg atataaaaga
    54061 atattcagga aaaatagaag gtattataga tatagcatgt agttccatcc ctgaaactta
    54121 tattttacct gattttatga agagtttttc tatgagttat ccagatgtaa aattttccat
    54181 aagccattat gattctcaat atgctatatc agaaatttta aatgaacgaa taagctttgg
    54241 attagttggt tctaaaatca ataatcctca aatagagtac ctagacttat tagatgatga
    54301 acttgttctt atcactcctt cagattttaa aattgataat aaaaataatt gtatcgatat
    54361 aggagaattg gcttatctga attttattat gagaaaagaa gggtctggta caagaaactt
    54421 aatactaaac acacttagta aaaataactt tccagtaaat aaattaaatg taatagctca
    54481 tgtagaatca aatgaggcta ttaaggaaat ggttaggtta ggtcttggag tatcctttat
    54541 atcgtacatt tcagctattg attatctcaa tgcaggcaaa ataaaatgct ataaaataaa
    54601 ggatgttgat tttactagaa aatttttctt tatttactct aaaaagaaaa ctttttcccc
    54661 attagaagat aaatttctaa acagattatg tgagtatttc gaaatcataa tataataact
    54721 ttaataaaac attgcttaat tttagattta caaccaatta ataatctaat tataactatc
    54781 acataaatac ttataaatta ttataaatca tctttctttt ttatttaatt tagtcaaaaa
    54841 atccctcatt caaatgaact tgggattttt ttgtttatac tactccaata gcagctaata
    54901 ctatacaaat aatcataact gaaattagta tcgtagttgt ctttaccttt tttcctaata
    54961 accaatacat aataccgaat atcatagctg gaagcataca tggcattatt tggtctaagt
    55021 aagtttgaat aggctctgcc cattctccac tacctacatt aacactaagt tttaacatta
    55081 cattagatgc agtcatacct ccaattacca taagtcctaa cattgaagct gcttccataa
    55141 cttttgaaac tatacttgaa ccactcacat ctttaaagaa ttgagttcca tacttaaatc
    55201 ctttatctag acatatataa cgtataataa aatgaggaac atttattatt aaaaggaaca
    55261 aaatcggtcc cattatgttg ccctgagaag ctaaagctat accaactcca gctgctataa
    55321 gctttaatgt tccccagaaa aatgaatctc ctattccaga aactggaccc attaaacttg
    55381 atttaacagc atttatacta ttagcatcaa attctttgtt ctttgcattt tcttcttcca
    55441 tagctccaga tatacctacc aaaagagtac ttatatgagg agtaactgac ataaattcta
    55501 aatgtctttt taaagcctta gatttctttt ctttatcatc tttatacaat ctacgtatta
    55561 ttggtgccat catgtatgca tatgctatat tttgcatacg ttcgtaattc caagatgaat
    55621 ctaatgtcaa tgaccttcta aaacatttcc aaaagtcttt cctcgttatt ttactgtctg
    55681 gtgaaattgt ctctaacttc ttagaactcg ttgtcatcta ctattacctc cttctctcct
    55741 acaaagttaa catatattaa ggctattgct aatccaaaca atgcaactcc tgttactgtt
    55801 atgtttaagt aagcaaccaa tataaatcct aataataaaa atgctactgt tttcttatta
    55861 agcatcattc tagctaacat ggcaaaacct attgctggta tcacacctgc tgcaacatcc
    55921 attccatgag ttacatatga tggtatgaat gaaagtattt tctctattac tggaacacct
    55981 aatgaaaatc ctattcctac tattattgct aatatcaatt tatttcctat accaaataat
    56041 aattgtatac gctctacacc ttcaatattc ccctcttctg cataacggtc agcaaggtga
    56101 gctccccaag taagtactac tgtcatcaag aagttatcta taagcaatac tagagttgct
    56161 ataggaactg caagtacaac tgctgctgat acatcttgac cagttaatat tacaaatgct
    56221 gtggcaataa tagacccaga tacaaaatca ggaggattac ttgctccaac aggaaatgca
    56281 cccataaata ctaattctaa tgttgaacct attactatac ctgtgtgtaa attacctagt
    56341 gctaaaccaa caagtggtgc aacaactata ggtctattat gcattgtaga acctacaaaa
    56401 ctatgcatat atgcaaagaa tgcaattaga gttatcaaaa taacttgtgt aaattccatt
    56461 ttcatccccc taaaattata ttaatttcat tacatttgta gcgtcatcat caggaactaa
    56521 ctgtacaaat acatttacgc cttctgaatc taactcttta atcatattta tatcatcttt
    56581 tgatacatgt actgctttag atatattttc acgattatca tctgattttg ttccaccaag
    56641 gtttatagat ttaatagctt ttacctcttt agcaagtcta taaacatctt ctacagattc
    56701 acaaagtatc aataagttat atttatcagt aacacctgag ttaagtgctt ttatagaatc
    56761 tgctatgctt ttcattacta gcttaacatt agatggttta gccattttaa gtcctgccat
    56821 tcgtaactca tcttttaata attcatcact tgctattaat atacagtctg tgcttaaaaa
    56881 ctttgtccac gtaaatgcta cttgtccatg tataagtctg tggtctactc ttactaattt
    56941 aatcattata attcctccct aatttttttg atttcatcca tgaatgtttt tacgtgttct
    57001 acactaacat ccccaaaatc tttgtaatta tctttaaagt aacttcctat tattgccata
    57061 tcacctaatt caagctgttt ttttgcattt tctaatgtaa ctccagcagc tataaccaat
    57121 gggaaatctc ctaaattttt acgaaacagt tctatttttt ccattgatgt ttcttgacct
    57181 gtagcatttt ctgtaactgc tatagcatca caccttgtca ttcctatttt taaatcttct
    57241 tcaatattat tttctgataa tactggttga tatttaaaac gtacgcctcc gattaaatat
    57301 gctggacatt tcgaacgttg taatttaaaa aattcttcta aagtagcctc atctctaggt
    57361 ttaacatgac ctactacaga atcaacctgt atataactgg cattatattt tgttgccagt
    57421 tcgaatccca tagtatcaac atttaaacag tttactccat atggtattga taaattagct
    57481 tttgatacat actcaagtat tctttctaaa tcataataat taccatagta attttctaac
    57541 attattccat ctacaccatt ttcttcaaaa attgcaatct cttttttagc tctttcaaag
    57601 atatcttctg gagtgtctcc ttttaagtgt atcattgcta taattggctt tttactttta
    57661 aatactgata atattccctt ttttttcata aactaaaata cctcttcttc ttctttaatt
    57721 tgtaatgtca cgctttgtat tcctcttcta gattcttcta ctaattggtc tatatcttca
    57781 actgttaatt catcagaaaa tcttgtaaga agttctagta ccatattcaa attcattcca
    57841 gaaaataact taacattatg tagattagtt aatcttaaca ttgctgtaca tacacttgct
    57901 ccatataagt cagataaaat tatatattca cattctttat cttctgatat tgttttttct
    57961 aattctaaag caaaatctga agcactttgt ccagggtata aaccatacga actaacacaa
    58021 tctgctaaat ctcctactat catttttact gcatttaaaa gcccttttga aaagtctcca
    58081 tgggatgcta atattatctt tttcatactt atcctcctac taaatataaa ttatatttct
    58141 gctgatactg catatttgta cttatcactt cttataaatt gctcattgta atataataca
    58201 tcattatttt ctgtatacac cgattgtctt actttcaata gtggcatatt acttgcacat
    58261 ttaagatggt cagaatattc tttgtttgaa tgttttacct caaatatatt ttctactcgc
    58321 ttaggtaatg tgcttatatt attagatata acctccatta aagatttatc ttctagttct
    58381 tcttttaata aaaacatata atctattcta aaataatcaa cttcaaaaat aacaggtact
    58441 tcatctatta atctaagtct tttgatacat attacctttt cttctagttc aatacttaaa
    58501 gcttcagcta cttgcttatc agcttttttt attaaaacag agattatttt agtgcttggt
    58561 tttgcattaa tacgatgaca agaattagta aaactatttc ctgcacatgt tgcttctatt
    58621 ctctctggta ttgttacata agttccttta ccacgttttt tacataatat atcttctttt
    58681 acaagttcat tgagtgcatt tctaactgtt atacgactta tattaaattc tttacataag
    58741 tctccttcag atggaagttt atctcctggt ttatatatgc cagatgctat ttgttttttt
    58801 atgttgtcat atagttgttg atataaagga acaaaggaat ttacttctaa atccatttct
    58861 tttttttgtc tcttttcatc cattttgctc acctccctat gtaacatttt tataacatta
    58921 tataacaagt tctttattac atattataac aagatgaaat cgttgtcaat ttttttttaa
    58981 ataattttta atttgacagt attttatttt attttctcca gtgtgacata ttgctatttt
    59041 tacaaaaaaa taagactgtt gtacaacagg ttaaattgtt tatacaacag tctttattaa
    59101 cttattatgc ttatattttt acttataaat ttatattaaa aaatgcctta tatcccttat
    59161 acatttcata tatgtctact ttagagacaa tctcatgtgg tgcatgcata tttaaaactc
    59221 caacaccaca atctataacc tctgcacctt ggtttgccaa tatatgggct atagttccgc
    59281 ctcctccttg gtctactttt ccaagttcag cagtttgcca tactacattt cctttattaa
    59341 aaattctctt tacttctgac ataaattcag cattagcatc attacatcca ctctttcctc
    59401 ttgaacctgt atacttagtt aaaactactc catttcccat atatgcagaa tttctctttt
    59461 catacgcttc tccaaaattt gggtcatatc cagcagaaac atcagctgat aataccttac
    59521 tatttgctaa agcccttctt actttaatat cacaataatc tccttctaaa gcaatcagtt
    59581 cagccacagt attttcaaaa aattttgagt gcatacctgt atttccttta gaaccaattt
    59641 cttctttatc tacacataat gcaactgaag taaactctgg ttgttcagtt tctaatatag
    59701 cttttacagc agcatatgaa cacaccctat catcatgccc atatcccaac accattgacc
    59761 tatcaagccc taaatctcta gccttaccag ctggaactac ttcaatttca gcacttaata
    59821 aatcctcttc aactatatta tatttttcat ttaaaatctt taatatattt gctgttatag
    59881 gttctttttc ttcatcatct aaaggaatat tcccaattaa tatatttaaa gcttctccac
    59941 taattccttc tgataatttc ttttgcattt ggtctccagc caaatgaatc aataggtcag
    60001 ttacacaaaa tactgggtca ttatcttctt ccccaataga tatctccact tttgttccat
    60061 catttaatat aacaattcca tgtaaagcaa gtggaacagc cgtccactga tattttttta
    60121 ttcctccata atagtgggtc ttaaaaaaac ctagattact ctcttgatac aatggatttg
    60181 gttttaaatc taatcttggt gaatctatat gacttcctat aatcttcata cctttttcta
    60241 tataattttt acctattaca aaaagtgcta ctgccttctc tttatttata acataaatct
    60301 tatcaccaca acttatgctt cctttttcca tagcttcatc tattgaaata tagccatttt
    60361 ctttagccaa ttttataatt tcttttactg aaagtctttc agtctttgac ttacttaaaa
    60421 attccatata attgcgagaa tattgcataa tttgttcaat agtattttct tttctttcaa
    60481 aatcccaagc attcttaaat tcgtacttta agttcatact ttcctcctac taaattctaa
    60541 tttttattgt ttttcatgta ttgctcatat tcttctggtg aaactacttt gacactatct
    60601 agtcttgacc taaagtgggc tctgaaattt tcaagatatt ctttccttaa aatttctctt
    60661 tctttgattt catcagcaga aaggattccc tctttatttt tctttgctaa ttcattaatc
    60721 ctatctaatt tctttttgtc aaacattttt tcctcctaaa aacttctatt tatttaataa
    60781 aataatttat tgctttttat atctaacttg tttttatatt cacaaaaaaa ctcatctata
    60841 ttatcactta ttatagatat tcccttttct agctcttcca tgcttggacg agctatattt
    60901 attctaaaaa atctatcatc tactagattg tcaaaaaaat aagtccctgg aagcattgac
    60961 acacctttgt ttaacataaa atttgtaaat gcttgagatg tatatcctct tggtaattct
    61021 aaaaaaaagt ttattcctcc acaagatttt ctaactttta atttaccact caatttctca
    61081 ttaatcaagt tttttgccaa tttatactta tcagtatata tcttctctat atgactcaaa
    61141 taatttttcc aatcaaaatt attcatatag taatacattg atttttgaat taaacctggt
    61201 gttgatatat ctgatgaata tttagcccat aaaacttttt ttaacaactc atttggcatt
    61261 tctacaattc ctatcctaag acctggcata agtatttttg aaaagctttt tatatatact
    61321 actctatttt tatcatcata acttctaatt gttctattgt ccattgattc aaaaacaaaa
    61381 tcacttataa aatcatcttc tattatataa aaatcatgtt cttctgccaa ttctattaat
    61441 ttcttttttt tatatgttga gtaagatatt ccggttggat tttgaaaatt aggcataatg
    61501 tatataagtc ttggttttat tttttccaac tttaatttta aaatacctat atcaattcca
    61561 tcatctagca taggtataga tattattttt gcacctctgc ttttaaacac ttcaattgct
    61621 ccattataag aaggttcttc cataaaaaca acatctgaat aacttataag acctttacaa
    61681 actatgtcta taccttgttg agcacctgat attatttgaa tattttcctt agtagttttt
    61741 atatttccat cacttagata ctccaccatc ttttctctta attcttcaga accaagacct
    61801 tcatcatatt caaatattga gctaccgtct ttagataatg ccatatttac agcattttta
    61861 aatgaatcaa taggaaacat atcattagat ggattcccat tgtcaaaatg aattaaatct
    61921 tctctttgca caataatctt attttttctg ttatctatac cgcttttata agaatttaaa
    61981 ctagatacaa aagttccact ccctataatt ttatatacat atccttcgtt ttctaaaagt
    62041 tcgtatacct taactatagt ggtgttgttt acttgtaaaa aatttgatag ttttcttatt
    62101 ggaggcaatt tttcgtgttc aactaactct ttatttatta tcaattcttt tatatgatta
    62161 aatatttgta tatatttagt tgattttttc tcatttaaat ctattctgta tttttccaaa
    62221 tttatcaccg ctcattgtat ttatatttta ttgatgcttt tacgtatatt tgatattatt
    62281 tagtatgtat atataatacc aaaattttta taaaaagggg aaatatttat gttttacgac
    62341 tatcacatgc actcaagttt ctctacagac ggaaaatcta caatggagga aatggtaaaa
    62401 aaatctattg aacttggttt ggaggaaatt tgtttcacag accatgttga ctatgatgta
    62461 tatgctgatg attccttttc aattgtctac gaagattatt ttaagagttt agagactctt
    62521 caaaacaaat ataaagataa aatatcaata aaaaaaggaa tcgaatttgg agttcaaact
    62581 caattaatag atacatacaa aaaggaagca catcaatatc cattggactt tataatatgt
    62641 tctatccatg ctatagatac aatggactta taccttggta attattttaa agataagact
    62701 caacacgaag tttacgaaaa ttactacctt tatttatata atattgttaa gaattataaa
    62761 gattactctg tcttaggtca tttagatttg attaaaaggt atgcacctta tgacactatt
    62821 ttagatgata gattattttc tgatataatt gaagaaaccc ttagacaagc tatttatgat
    62881 ggcaaaggta tcgagataaa tacctcttgt tatagatata atcttccaga cctaacccca
    62941 tctaagtata tccttcaaat gtacaaagac ttgggagggg aaatcataac tacaggttca
    63001 gattcacatc atataagtca agttgcatgt gagtttgact acatatattc attactaaaa
    63061 aatatgggat ttaaatatgt atctaaattt aataaattga aaccagaatt tataaaatta
    63121 taaattttta cacctccttg tgaatatatt taaaagataa ggaggtgatt ttttgaaagt
    63181 accttattta gtactatcaa cagttatttt atttatatcc aattttattg taagaatatt
    63241 tggtttttta tataaaatat tcttatcaag agcactaggt gaaacaggtc taggtatcta
    63301 tcatatgatt tttaactttt tgatgatttg cttagctgtt acaacaacag gtatacctac
    63361 tgcacttagt tgtctagttg caaaaagaaa agctttaaat gatagacaca atactaatgc
    63421 tttatttata tcaactttat atatatcatt tttcgtagca ctaactatat ctatagttgc
    63481 atctttcaac agttcttttt tatcaattaa gtttttaaaa gatgctaaat taaacctatt
    63541 tatactagct gtttgtcctg ctatagttat aataactatt tcaaatgtac taagaggata
    63601 ttactatggc ataaagaatg taaaaatccc tgctattgga caaatcattg aacaaattgg
    63661 taaaatatta tttgtttttt tacttgttat gtacataaat aataaatcta tgaattgtta
    63721 tatagcccta ttaggtatat caattggtga gttgagcaac attatattta tgcttatttg
    63781 cttatggcga gattcatcat ttgacaatag gtatattata agcataaaag atttttataa
    63841 ttcttctatg gaaacattaa aaatgtccat tcccataact tgtaatagaa tgtcaaacat
    63901 acttttgcaa tctataagtt ctatgatgat accatcaaga ttagcattat caggaatgac
    63961 ttatcaacaa tctttaagta tgtatggcgt catcagtggt atggtaatgc cttttatatt
    64021 tttacctttt actgttggtt cagcgcttat tgtaaattta ataccaacta tttcacagga
    64081 aatggctcta agaaagcgta agagtgtaat taaaaaaatc aaatactcaa tacttcttac
    64141 tttatttgta ggcatactat catcaatatt tttttatttc tttggaaaag atttatgtat
    64201 attagtattt aaaaatacac ttgcaggaga atatctaaaa gctatgtttt tagttccact
    64261 atttatgtca ctaaatcaaa ctctatctgg cattttacat tcaataagaa aagaattagc
    64321 ttcaagtata aatactatca ctggtatgtt aattcaactg atagctttat atgtatttct
    64381 tccaattcca ggacttaata tttatgcata tatatacaca atgacgatag tatcaatctt
    64441 tacttgtcta ttacatacta tagtgctttt taaatcacta aaagctatac actagttata
    64501 aaaacgtgaa ggctaccaat gtaaattata cattttggta gccttcctta gatgattttt
    64561 atttataatt taaactgtct atatctctac ctatctatct gtggcaactt ggctttccac
    64621 tttcatgatt aggtccacat tgcgaaaaat cacatacttt agagaaagta tcaacaagtc
    64681 ttggttggat tggatttggt gatgctaaaa ctactatttg ttcacttatt aatgtgctaa
    64741 ctgtattttg taagcaaagt actaaatcta tatcatttgg tattattaat tcatagaaag
    64801 gttcacaaca ttcgttacat tctaatttta atatagattt tcctatacaa tctacagtta
    64861 agttagtttg atattcttgt cttaaagtaa cagctcttcc gtcagctggc aagcatattg
    64921 gtgctgaaag tgtgttaaaa gtaaattcta cataatcaac tcttctctta catccacctc
    64981 ctgctctaac tgctgggaaa gctaatgcaa cgaactctgt acatccacat ctacctctta
    65041 gctctagtac taaattacga actgctacag ttaatcctct ttgtttataa gctactgatt
    65101 ttccttttcc ttgtctacag cactcagcat ttctttctcc acaaactgca aattcaaaag
    65161 ttgtttcaca gtttcttcct actatatctc ctaatgggtc taaatcgaaa tcttctaaag
    65221 ttgtcattcc tgtatctata actattccat cattacttaa acatattttt tctatagtta
    65281 cacttgcttt acctgcactt ggaactgaac caaatacttc tactacttct gtttcaaaag
    65341 ttaatggctc tccatttggt cctgttgcat ctgtaaatgt ttggaattgc atagtatcaa
    65401 atattctatt agcctctatt gcaaatggca ctgcatttga tacagagaag tttcttggag
    65461 atataggatt acagcattct ggtccacatt tgttttcaaa acattcatct gaatccattt
    65521 cacatggttc acaatcacat ttacaatggt catggcatcc acaattgtca tcacatggat
    65581 taggtttgca tgggttgcat ggattaggtt tacatgggtt acatggatta ggtttacatg
    65641 gattacatgg tttgcaatca tcatgacaat cacatttatt atcagtatta cattcattat
    65701 gatgatgtga ttttttaaac cctctcatat cttctgaatt tatttcctct gtatacactt
    65761 cttcttcatt cattgtaggc attggctgat ttgtcattct tcttttattt tttttataat
    65821 cttgcatttt ttattgccct ccctgtaagc gattcttatt aagtctttgg ctttttaaag
    65881 cctaattaat actatgctct tttgagctta attgttactt cgctttttaa atctatcaat
    65941 aattagtcag atttagtaaa aaaatgcatt tttaataaaa aaagtactac tatttgaaat
    66001 agtagcactt tttttgtccc gaaacaccgg tggctaagta aattcacacc ctaggcactc
    66061 ccaggtgggt gacttgccag taacctttaa cgtccaaact aactaggcat gttataattt
    66121 accagacacg gtctcccgta tttcatttgt aggttgaatt taaaaaagcc ttatcgtatg
    66181 tttcaggatt tcatattatt attatataat aaattttgaa ttttttaaag tggttttata
    66241 tagtaattga gataatctta ttctatcatt actttttctt ccttttttct ttatgtattt
    66301 agttaattat cgttttttct tagttctggt tttagtattt tttgcattat aattgtattc
    66361 ggattcttgc tcattaatgt tgtatagctc ctcatcatat actatatctt catcattttc
    66421 tatattttca tagtctgttt tattatcctc gactaattca tcttcattat cctccatttc
    66481 atcttcgtct gttaactctt catcatcata atccaattct ttgtcttcat agtctaattc
    66541 ctcatcttca ttattcaacc cttcattatt gtcttcatct tcattattac tatcatcacc
    66601 tcttaaaaga cttcctaaca atttgagatt attcatactg ccaagattgt ttatatttgc
    66661 caaagagctt aaactaaatc cgccttcacc aaagtcatct ggtaaaaata attctgcaaa
    66721 taaatctatc ttctttttca ttcctatagc tttttcaact gaattttttc ttttttctgg
    66781 gaatacatct ataatttcct ttatcatcat attcttttta tcatcactat ccatttttct
    66841 gaaaaaatcc gtttcatctt ctatatctac catatctata ttatttaatt tttttattcc
    66901 tctaaccaaa tctaaaacac tttctatttt tattagtatt tttctttcat cttttgacat
    66961 gtacttttta gttcttgtta ttatttccat tcccatttct aaatcttctt cacttaaatc
    67021 catgagcctt aagcctcttt ttatgtcatt tgcatcaaac cttaaattgc tatgtgtaga
    67081 ctgtgacagt ttatcatttg catttttttt gttttttcta actctattat ttccttttga
    67141 tttattttta tcatcaaata tagagatatt accattactc aatgcaatca ctccaatcaa
    67201 aaatagtaag ttattcaaga caattccccc ttatattata taattgccct atattaaagt
    67261 atgtttttca tattttaatg ttccattttt aaagctcagt gcatatatat tatctataag
    67321 aatttttatt tatattatat atcactcaca attcaccact tcaatattat ttctatatat
    67381 aaatagtatg aatataattc aatatatatt tatagaaagg ggttttttta tgaaaaaatt
    67441 agatgcagag tcattagaaa aaatggctaa acaaaaaaat attgacaagg ataaaataga
    67501 aaagatggct gatagttaca aaggaaaatc agaaaatgaa cttatggagg aacttataaa
    67561 aataggtaaa aacttagatg gaagagatga agtagtatca aaattcaaag cgtttttaga
    67621 tgaaaatcaa cgcaaaaaat tggatactat aatggaaaaa atctcagatg cagaaactca
    67681 gagagatact aaaccagcta aaactaagaa aactaaacct actaaaggta agtcaaattc
    67741 acctgcacca aaaaatacac caactggtca acagaaaaaa tctaaaggtt tatttaagaa
    67801 aactaaaaag tctaaccctc atgaatagat aaaataaact atttaaataa ttagacaatt
    67861 atttttagtt aatctagtat taaatttgat attattaaca agaaaaatca ggtagtgctc
    67921 taagcactac ctgattgatt ttaatagttt tatttttttc tttctatgac actttctcta
    67981 tcaacaattc tataaggtaa ttctattttc ttattttcaa ttaattcctt atttattaac
    68041 tttatgacca ttcttattgc tactgctccc atatcgtata aaggttgata tactgtagta
    68101 agtttaggtc tatacatttt agctatctta acatcattaa atcctgaaac tgatatatct
    68161 tctggaactt tatatccagc atcacatata gcatttatag cacctatagc agcctcatca
    68221 cctgttacaa aagccgcatg aggtattatt ccatcatcta atagttcttt catactattg
    68281 tatccactct cataatcagt tccaccatac ttaatcaaac tcttgtctaa ttctatattg
    68341 ttgtttgaaa gtgctttctc ataaccagca agtctttcca tttctaaaac agtatcatct
    68401 ttactagtca ttataaaagc tatcttttca tgacctttct ttataagatg ctctgtcata
    68461 tcaaaagtag cttcttcgtt actagtactt actgtatata tatcataatt tctagcagtt
    68521 ttacttatat atgtcgctgg tattccacaa ttttgtatat agttgatatg ctcttgttca
    68581 actatccacg aaatcataac tataccttcc acttgttttg ctctcaatag atttatactc
    68641 ttaagttctt gctctttatc agagtatgta ttcgctaaaa gaatatcata gtcatacatt
    68701 ttagcaacct cttctattcc atttaacacc tcattaacaa aagaatctga aacttctgga
    68761 actattaccc ctattaattg acttttcttt gttactaaac ttctagcaag cggatttggt
    68821 atatatccag tctcttttat aacctctaaa actttttgtt tgacttcatc agttacaggt
    68881 tttgaatcat ttataactct agatacagta gatattgaca ctcctgcttg tttagcaaca
    68941 tcttttatcg ttatattgcc tttcatcttc atcctcctta ttttactaaa tttatctaaa
    69001 actgaaccaa atttttgaag gttcctattt taactacatt tatataagtt tttattttac
    69061 cataaaagca agtacattta aatacattat attttatatt ataccctata ttcaacaaat
    69121 ttaataatat tcattcttaa tttaaatcat attaaaaaat aaaataaaaa aaatactggt
    69181 ataaaatacc agcatttttt attataatta tttcagtatt agcagccgca gcccacttca
    69241 ccatcaaaga atccaccact tgaacaagtt attagtaata atattaagaa aggtatccat
    69301 gacattatgt caatgtctct ccagcaatct tcaaaagcta agaataggaa gaatagtact
    69361 attatccacc atcctcctcc accaaaacat ccttcttctc caaaaaatct atctaacata
    69421 acaaagccct ccttttttta ataactgtac tcttattcta agcatccacc acagcagcaa
    69481 agtattaata aaactattag gaatggtatc catgccatta tgtcaaattc tgcccagcta
    69541 tctccaaaag ctaagaatag gaagaatagt actattatcc accatcctcc tccaccaaaa
    69601 catccttctt ctccaaagaa tctatctaac attatacgtt acctcctgtt gatattttgt
    69661 tgagcttttc gctcctaaca tatactatgc attgggtttc cattttgcta atgtattttt
    69721 attttttttt aaaatttttt aatctgaatt aaaaaaggca aaaccataac ttgtataagt
    69781 tactggtttt acctatttaa taatcaatat tttttagcaa caacaaccat catcgaagtt
    69841 aaataataac aacactatta atataaccca tatccatata ttgtcatcac ataataaatc
    69901 ttctaaaatg tctgtgcata ataataagaa tactataact attattatca acattttatt
    69961 accaaaaaat ccttcgcatc ctccaaagaa acgttccata ttgtcttcta attttgtcat
    70021 aactaatcct ccttgaatca ttaagagact aagttttgtc tctttaatta aatatatgta
    70081 gtaatagaca gataagttac ttctaaaaaa tttttattga ttagtttatt tatttctttt
    70141 tcaccaagtt tattgtatct atcaacttca tcaagataat cttttttctc ctctgatata
    70201 gtatagatta aactttctat tgattttatt ttgtactcct tatatctttc tatcaagaag
    70261 gatgtttttg aattttctat tcctttcttt acatgcatta accttgatat gtagtcttct
    70321 ttttcattag atacataact ctccttttca gctacatctt caaggattaa attggtctcc
    70381 attacataat cctctatacg ttgcatatct aaagttattg aattataata aaaatttact
    70441 gctataagta aaaacattcc tattgaagtt agtaatagtc ctacatattt catagcattt
    70501 cctcctaagt tatatttgtt atcaataaag tttattcatc aaataatact ttattactac
    70561 atttataaaa ttttattatt ttttatagat tccatattga aaaattcttg atattatatt
    70621 aaactaacat taaaattaat taaaactgct ttaggaggct taaaatgttt gaaaaaataa
    70681 aagaaataat agcagaacaa ttaggggtag acaatttaga tgagataact atggaagcat
    70741 ctctaatgga tgacttagaa gccgattcat tagatgctgt tgaaattatt atggcacttg
    70801 aagatgaatt tggaatagag ataccagacg aggaagctga gaattttaaa tgtattggtg
    70861 atatatgtaa atatatcgaa gaaaacaaat aatatcgttt tgtctacaaa tataaatagt
    70921 ctgtgtaaac ttctacataa taaattatat tagagttcac acagactaga ttagattgat
    70981 tcacaatata caagagataa tctcttatat ttaatttata caaatatata aattactttt
    71041 cttcataaaa cgtcacattc tttattatta tatctatagt cccatcttga ttttgtttta
    71101 cagtatactt cattgggtct tcaaaatcag ttagattccc ttttatatca aaaccattat
    71161 ccgtttttat acttcttttt ttaagctttt tctcaaccca ttttttatct atactaaaac
    71221 tttcatcaag acctttttct tccatatgct ctttaaagct atcttttaac tcatcatctt
    71281 taattgaatt atcaacaaag tcatttatat caacttcatg tttttccttt agtgtataat
    71341 ttaatatact tcttacatct tcagcttgct ttatatcatt actaagagca ttggttatcc
    71401 aattttcagc tgtattttta aacaccttgg tcttgtactt atcatcatct atttttttag
    71461 catttaaaaa ttctgtcaca aacttagatt ctgacccttc tttttcagca tccttatcta
    71521 aaagccttag atgaaactca tcatttatgc cacttaaact aatcaaagct ccttgctttt
    71581 gtcttaaagt ctctggtata ccaatttcat ttggaaccat ttgaatatta aatttatcat
    71641 ctacaaattc aattgaatga gtgtacaact ttttataatc taatttaagt atagctacac
    71701 tcttttcatc tttaatagtg tataaacaaa ttgccaaatc acaagattct agtgcagcat
    71761 taattttcat aacatcaaac aaataagatg caatttcttt agaatttttc aaaaaagtac
    71821 tttcatcata tattatttgt tcacaacagt ttttaattaa attatcatta taatctttaa
    71881 aaacaccttt tcttaaatcc tcatcttttg caattctttt tatggctttc tggaaaaaac
    71941 catctacctc ttgattaact ttgccttcaa agtcatttaa tattggaaca tcactatttt
    72001 tgtccaaaac atgtattata aatttatgta ttatcatata tatcacccca ttatcttaat
    72061 ttcgatatta actcttttat atcctctggt atatctgctt taaattttaa tttttctttt
    72121 gttcttggtt gttcaaactc tagcctgtat gcatgaagtg cctgcctatt tataagttct
    72181 tcatctacac aaccatacaa ctcatcacct attattccat gacctatatg agccatatgt
    72241 acccttattt gatgtgttct accagtttct aagcttactt ctaataccgt tgcattttct
    72301 agtctttcta ttactttata gtgagtaaca gatgattgtc ctctttcatc tattatcctc
    72361 tttattgaat cttctgtagg tctataaatt ggctcatcta tagttccctc attttctttt
    72421 ataattccat caactactgt tatatacttt ttttcaactt tattttcact cattgctgtg
    72481 gataaagtat gatgtgcata agcatttttt gctacaataa ctaaccctga agtattcata
    72541 tctaacctat ttacaaatct tatttttaca ttttcttttt gattatctat atagtaacta
    72601 ataccatttg ctattgtttt atcatagtgg ctttttgttg gatgaactac cataaatgga
    72661 agtttattca ccataattat atcaaaatca tcataaatta tctgtaaatt taaatcttga
    72721 ggttcaaaat ttgctttttc ctcatttatt tttacttcta ttaaatcacc actatacact
    72781 tttaaactcg gctttttata tactccattt actaaaacac tcttttccct cttcattttt
    72841 gataatgacc taactgagaa atttagcttg tccaataaaa cttcttttaa agtcatttct
    72901 tcttcatttg tatacgatat aagattatat ctttgattct cttttttaaa caaactttta
    72961 cctactttct tttatgtctt cctacttttt ttatatcttt aaaatcatga tattatatat
    73021 tttacaccat ttttgtttaa tagataataa ttatttttaa ctataaaaac ctgtaagaat
    73081 aacaaatagt tattcttaca ggttaaattc atagttaaat atttaatttg taaatattat
    73141 aatctaaaac tatctcttaa ctattaaact agttcccatt ccaccaccta tacaaagtgt
    73201 agcaagacca gttttagcat ctcttctctt catttcatat aaaagtgtag taagtattct
    73261 tgctcctgag catcctattg gatgtcctat agctattgct ccaccattaa cattaacttt
    73321 attcatatct atatttaagt ctcttattac agctacagat tgagcagcaa atgcctcatt
    73381 agcttcaact aaatctatat cttcaatagt catattagca gcttctaaag cttttttagt
    73441 tgctggaact ggtccatatc ccattatttt agggtcaacg ccagctgttc cataagaaac
    73501 tatagttgca agaggctcta ttcctagttc ttcagctttt tctttagcca ttactactag
    73561 catagcagca ccatcattta ttcctgatgc attaccagca gtaactgttc catctttttt
    73621 aaatgcaggt cttaatttag caagtttctc cattgtagta ccaggcttaa tatattcatc
    73681 tttatctact acagtgtcac cttttcttcc ttttataaca acaggaacta tttcttcatc
    73741 aaattttcct tcagcttgag ctttttcagc tttattttga cttgcaagag ctaattcatc
    73801 ttgttcttct ctagttatat tccattgctc tgctatattt tcagcagtaa tacccatgtg
    73861 atagttatta aatatgtctg ataatccatc ttttatcatt gaatcaacaa aagcagcatc
    73921 acccattctt gcaccatatc tcgcacttgg tactaaataa ggagacatac tcatattttc
    73981 agctccacca actaacatta tatcagcatc acccaatgct ataagctgag atgccattga
    74041 aacagatctt aatccagaac cacaaactat atttatagtc atagctggtt tttctactgg
    74101 tattcctgct cctaatgcta tttgtcttgc tatattttgt ccaagacctg ctgtaagtac
    74161 tccccctaaa agagattcat ctatcatatc tggagttata ttagctcttt ttatagcttc
    74221 tttagctgct gttaccccta actctaccgc tgaaactgat ttaaatgctc ctccaaaact
    74281 tcctactgct gttctagctg cactggcaat tactacttct ctcatattca ttacccccat
    74341 taaattagat ttttcatata tccgaaattg tttttttaaa caattttatt taaattttta
    74401 attcccaaac tcttatttat tataatcata gaatcctatc ttagtttttc ttcctaattg
    74461 attagctcta accattttag ctaaaagtgg atgaggtcta tatttagtat ctccaaactc
    74521 agtatataaa acattcatta tagctaaaac aacatctaat ccgattaaat cacctaatgc
    74581 tagtggtccc attggatggt ttgctcctaa tttcatagct tcatctattt cttctttact
    74641 tgcaacacca tccgcatata taccaacagc ttcatttatc ataggtataa gtattctatt
    74701 tactacaaat ccaggagatt cagatacatc tactggtact ttattgatac tcttagataa
    74761 ttcaaatact gtatcaaaag taacttttga tgttaactga ccacttataa cttcaactaa
    74821 tttcatcata ggaactggat tgaagaaatg cattcctata actttatctg gtctcttagt
    74881 agaagaagct atttctgtta tagataatga tgaagtattt gttgccaaga tagtatcttc
    74941 tttacataat tcatctagta acttaaaaac atctttcttt atattcatat cttctacaga
    75001 tgcttctatt attaaatcca tatcttttaa atcttcatag ttagtagttg aactaacatg
    75061 acttaatatt tctgcttttg tagcctcatc catttttccc ttagtaacta acttagttaa
    75121 atttttatct aataaagcta aacatttatc tatagcacct tgagttctac tctttaaaca
    75181 tacatcatgt ccacaacttg caaaagtttg tacaatacca cttcccatag ttccactacc
    75241 tattacagct aatttcatag ttataacctc ctgttatttt agtatttata ttctgttaac
    75301 tagattaaaa tactattcaa tctagttaac agcaaatata tttttaatta gatttttacc
    75361 cttttataaa gttggcttct ctcttttcaa cgaaagctga cattccttct ttttggtctt
    75421 tagttgaaaa acaaagtcca aataaattag attctatatc tattccagta tttatatcag
    75481 tttgagcacc aagttgtatt gcttctttag agtatctaac tgcaagttga gcatttttag
    75541 ctattatctt agctaatttc tcaacctctt ctattaaaat ttctggctca acgactctat
    75601 ttactagccc tattttttca gcttcatcag cttttataac ttgacctgta aagattaatt
    75661 cttttgcttt tgccattcca accaatcttg taagtctttg agtccctcca tatcctggag
    75721 ttattccaag agttacttct ggttgaccaa atttagcttt agcagatgca attcttatat
    75781 cacatgccat tgcaagttcg catcctccac ctaaagcaaa tccatttaca gcagctatca
    75841 ctactttttt actattttct atctctccaa aagcttttgc tcctaatata ctaaaatctt
    75901 tagcagctac agcatctaaa tctttcatgt atgcaatatc tgctccagct acaaatgcct
    75961 ttccttcccc tgtcaatatt acaacatcaa tagtttcatc attattaata tctacaaata
    76021 cttcataaag ttcttctaaa gtctttgaat ttattgcatt aagggcttta ggtctattca
    76081 ttttaactgt acatatattt ccatttactt caacagctac attctcataa actttaacat
    76141 cacttgtact cataataccc tccccaagaa attagttagc taaaacttca cctttttctt
    76201 ttgcaacact taactgactg ataagttctg gaagtacttt atgaacatct ccaactatac
    76261 caacatcagc atatttaaat attggagctt ctggattttt atttatagca actataaact
    76321 cagcatcttc cataccagct atatgttgta ttgctccaga tataccacat gctatataaa
    76381 ggtctggtct tacagtttta ccagtttgac caacttgtct tgctttatct aaccaacctg
    76441 catctatagt ggcacgagaa ccagaaactt ctccacctat aatttcagct aattcataaa
    76501 gtatgtctaa gttttctttt ccacccattc cacgtccagc agaaactaat atcttagcat
    76561 cttctatttt aacttgtttc ttagcttctt ttattacttc tacaacttga actaatttat
    76621 cagcatcatt aaattctacc ttgaaacgat taattacagc ttctttagtt tcgtcaggtt
    76681 catttttctt cataactcct ggtctaactg tagacatttg aggtctgaaa tctttacaaa
    76741 ctattgttgc cattatattt ccaccaaaag caggtcttgt cattaataat aattttgtat
    76801 cttcagctac tgcaagacct gtacagtcag cagtaagacc tgtatgtatt ctagcagaaa
    76861 ctctaggtgc taaatctcta cctattgaag ttgcaccaaa taatacaact atagggtcag
    76921 ctgcttttat tgcttcataa gctgcttttg tatatggttc agttgtatac actgctaaag
    76981 cttcatcatc tactactatt acctcatctg caccataatg tgctaatgta tctattaaac
    77041 cttctacctt actacctaaa agtaatgcag aaacttttgt atcatagtct tttgctattt
    77101 ctgtagcctt tcctagtaat tctaaagaaa cagtttgaat tacattttct ctttgttcta
    77161 ttactactaa aacgttaccc attctttatc cccccttaaa ttatatgata tacttctctt
    77221 ttaatttatc tatgataatt ccagctgatg ttttcgcatc ttcattgtat attgtaccag
    77281 ctggtttaac tgattttgta aatgatttaa atacactagt tggagaacct ttaagaccta
    77341 aattagaagg gtcaacctct atatctttta cagtccatgt ttctactaca tcattttcga
    77401 aagcatcata tattcttcca actttcatgt atcttggtgt gttcatatct ttaagagttg
    77461 ttataaggca tggcatttta acttttaagt catggcaaca atcttcaaat tgtcttttta
    77521 ctaatacata ttcaccttca gtttttattt cttcagcata tgttattgat ggaagattta
    77581 aatgttcagc tatttgaggt ccaacttgtg cagtatctcc atctatcgcc tgtcttccag
    77641 ctattataat atcaaaatct atatttttta atgctcctgc taatgctgat gaagttgccc
    77701 aagtatcagc acctgcaaat gctctatctg ttaataatat tcctctatct gcacccattg
    77761 ctaaagcttc ttttaaagcc atatctgctt gaggaggtcc cattgttata acagttacat
    77821 gagcacccat ttcttctttt aattttatag cttcttctaa acctgcttta tcatcagggt
    77881 ttattatact tggtactcca tctctaatta aagtacctgt attaggatct agtttaactt
    77941 ctgttgtatc tggaacttgt tttatacaaa cgactatatt cataaatcct tcctccatat
    78001 ctattttaat atcgacctat tgtgtatatt ttaatattta tctattttaa taattttcct
    78061 gaaataacca ttctttgaac ttcactagtt ccttcatata tttcagttat cttagcatct
    78121 ctcatcattc tttctactgg atagtcacga gtgtatccat atcctccatg aagttgtaca
    78181 gcttttgtag taacttccat agctgtttca gcggcaaata attttgccat tgctgcttct
    78241 actccataag gttttcctaa gtctttattt atagctgctt gatatacaag gtgtctagcc
    78301 gcctgtacct taacttccat gtcagctaat tggaattgtg tattttggaa ttttgataat
    78361 ggtctaccaa attgtactct ttcttttaca tatttaacag tttcatcaag agcaccttgt
    78421 gctaaaccta aagcttgtgc agctatacca attctaccac catcaagagt agacattgct
    78481 atcttaaatc cttgaccttc ttttccaagt aaattttctt taggtattct gcaatcctca
    78541 aatattaact cactagtagc tgaacctctt atacccattt tcttttcttt aactccaaag
    78601 ctaaatccag gagttccttt ttcaactata aatgctgata tgcctttgtt ccccttagat
    78661 ttatcagtca ttgccattac tacatatatg tcaccagcta ttgcatttgt tataaatatt
    78721 tttgagccat taagtatgta ttcatcccca tctaaaacag cagttgtttg ttggccagac
    78781 gcatctgtac cagcattagg ctcagtaaga ccaaatgctc ctaatttttc tccacttgct
    78841 agtggtctta agaatttttg tttttgttct tcattaccat attgatatat aggccatgaa
    78901 ccaagagatg tatgagctga taatataact cctgtagtac cacaaactct agacaattct
    78961 tcaactgcca ttatatatcc tacagtgtct ccaccttctc caccatattc ttttggatac
    79021 ggtataccca tcattcctgc ttttgccatc ttttccactg tttcataagg aaatctttct
    79081 tcttcatcaa gttctgttgc taaaggttta acttcatttt cagcgaagct tacatataac
    79141 tctttaagca tctgatattt tttagaattt aaatccataa tagcctcctc agtattttat
    79201 aaatatttta ttttcattta ttaattaaaa tctcggcaac atctataata aagtatttga
    79261 atatacgtcg agaaatttat aaccttaatc aaactacgct ctatatttat atgtgattat
    79321 actaaccaat tatgacatta atttaatcac aaattgttaa tttaaaatca actacaccta
    79381 aaaaaaatct cgctttttgg aattttgtga aatttcaagt taaaataaga tttctttcac
    79441 attgattaca aataaaataa tttgtttaca atatttatat cagggtatac taaatagtaa
    79501 atattgtgtg tatagctgtt ttttagccat gtacagaata tttttatcgc ataaaaatta
    79561 ttttaataaa gctaaataat catattttta tctgactatt ttttattttt aaatatctta
    79621 catttataat agtatcactc aaaggataat ttttcaataa tttctaatta tttttttaac
    79681 aatatttatt acattttttc cacttttttg tcattttttt attgtttcga aaaaaaatca
    79741 gaatttttta actttatttt ggattattag tttaaattag attttcctct tagatttata
    79801 aatatttaca caaaaaacta cctctgcata gattgtatac agagatagtt ttttactaat
    79861 ttctactata gtttactata tttttttacc aatttttaca aacatctacc catttttcac
    79921 acttagaaaa cttctccatt tcttcacatg taagttctat tgcagagtta ctactaccac
    79981 atgcaggaaa tactgtatca aatctcttca ttgaatcatc taagtacact tttagagaat
    80041 tttttaaacc aaatggacaa acaccaccaa tagcatgtcc agtaaactcc aagacttctt
    80101 ctggtatcaa cattttagcc ttacaattaa attcagcctt atacttctta ttgtcaatct
    80161 tagcatcacc agctgtcaca attaaaattg catcatctcc tattttgaat gagagtgtct
    80221 tagctattct tgctggaata accccagctg cttcagctgc aagttctaca gtagcactag
    80281 attgttcaaa ttctaatata ctgtcgtcct tgccaaattg tttaaaatac tctcttacat
    80341 tacttattga cattaaatct ccctcctagt ctgaactttt ataaatttca tattattctt
    80401 aattatatct ataattgatt tatttttcaa attattccat aatattagca ttccatgtat
    80461 cattattttt tccaactact agatacagtc cttttgccat tggaatatta acaacatatt
    80521 ctcccttata ttctacactc ataccagatt cgttaaagta cctataatca aaatttagtc
    80581 cttttggaat tacaaaatca acataacctt gattgtttgg ttttattcca tacttcagag
    80641 ttctttcagt tatagaattt ttttcattaa ataaatctat attcacatat gaagaacact
    80701 tatttattcc ctttttattt tccacacaat tttcaaactt cattttagca ctgtttaatt
    80761 tataactata tttactatta ttacttattt taaatcttac aatagtacca atatctctgc
    80821 ttctcctgct atcaaaatca aaaacaattt cctctaaatg atttatttca taatctttga
    80881 cacttaccat atctctatat actaatttat ttatagctat gaatagtgta aaaatcccaa
    80941 aaataaaaaa tgaaactttt ataaactttt tcatttctag tctccttata ttttgtgcta
    81001 ttgtgctata atattaattt aaattttaat aattaaactt attctttttt gaaatcctaa
    81061 tagaaaaata cattgatatt ataaaaatta ttattgttaa aaatgtcata ctatataaat
    81121 ttatatactt agcattagcc atatcagtta cataatttga aagatatact cctccaactt
    81181 tactataatt aaaatgcttt acttgatata caatcatact aatcatcttc aaaagacttc
    81241 catatacaaa ataaattaaa atacttacta taagaccaca aactttcatt tttccatatc
    81301 caaacttaaa aattaaagga agtaaaatcg tcaaaattgc taaaaatata tttacagaaa
    81361 aaaatacatc atttaaaacc atatttctaa agaatactaa tgatgtcaat ttactcatta
    81421 aggacacaat tattgttaca gaaattatta gtcctacacc taataaatat tttgagtaaa
    81481 ctatatcttc tatgctaact ggcatactcc ttataaaaat ccttgaatca ttttcataat
    81541 cacactcaaa cgtatttata aatatcagat aactaacgac aatacttact gtataatatg
    81601 aaattgaatt aaggaaaaaa taaaacacaa aaaatagcaa tatgtacttt aaattacgga
    81661 taccatctga actaatccct attattaaat cttttcttat taaattgaac atcatctcac
    81721 ctcatttaca taataataca ttagttcttc tatagtagga tttttgacct tatgcttatc
    81781 aatttctatc aataggcttt ttactttcaa gctatctcca actttaacaa gtgcctcatt
    81841 ataatattta tactctttaa caccaactat actttcttta attgcttcta gctctgcttt
    81901 atttgcccta attattttat attcttgttc tattaattct ttcttaacag taaaaatctg
    81961 atttcctcta tttataaaaa caagataatc agcaatttta attagattat cagtattatg
    82021 agtagaaatt attacactac tacttccatt tttaacaaaa tcttgtaaat actgcattat
    82081 ttcactcctt acaattgggt ctatcccagt agttggttca tccaaaatca ataacttagc
    82141 attatgacta agtgcacttg ataacataag cttctcagat tgacctttag ataaattttt
    82201 aatatgcata ttttcctcta tatcaaactt attaaggtat tcatcaaatc tttctctatc
    82261 aaactcctta tagaataaag aaactatttt tctaaattcc ttaaccttta aatgtggata
    82321 aaattgtaaa gaatcatata caaaaccaat attgttttta aaacttattg gagaattttc
    82381 aatagtttca ttacaaagtt caatttctcc ttcatctgca tcaataatcc ccattataat
    82441 ttttattaaa gtcgtttttc cagaaccatt tggtcctata attccaacaa tatccccttc
    82501 ctttaactct aagtttatat tatttaactt gaattttcct aatttttttg tgatattcct
    82561 tatgctaaac acatcttcac ctcttacgca ttttttatac ccacctatac atattttaac
    82621 acattcacta caaaggtcat ttataaattt ataaattaag aattataaaa ctatgttata
    82681 atacaaagta tgaagaggtg aatatatgaa aagaattata actataaata caaaccaatt
    82741 aaataaatcc cttgagacta aagaactctt aactagaaaa cttatcaatg ctggctttga
    82801 agtgtattca gatatttatc cagatacaga gcttattata tcaattggtg gtgatggctc
    82861 ttttttaaga acagttagag atttcgattt tcctgagatt cccataatgg gaataaatac
    82921 agggcatctg ggtttttttc ctgatatttt accagataag attgatagtt ttattgaagc
    82981 ttatacaaaa aaagattata ttattcaaga aatgtcactt cttaatgcag aagtatatac
    83041 aactactagt ggttctaata tgcttgctgt aaatgaggtt gttataagag gagacaagtc
    83101 taggactata cacctaaatt taagccttga taataaacat atacaaaatt ttagtggaga
    83161 tggtatgatt atttctactt ccacaggttc aacagcctac aattattctg ctggaggtag
    83221 tattgttgat ataaatcttg aacttatgca gattacacct ttacatccga taaacaccaa
    83281 tgcatatagg tgctttacat caagcataat atgttcaaat gaatctgtta taaaaattgc
    83341 accagaatat agatttgaag attctgtatt gattgtcgtt gatggagttg agcatagatt
    83401 tagacaaatc gaaaacataa aagttagtat ttctgatgca aaaataaaat tacttagaat
    83461 gtcaaactat gagttttggc atagagtatc tgaaaaattt ttatagactg tacttaggag
    83521 gatttttaat atgaaaatag gaataatgag tgatactcat ggtagcttac tttactttga
    83581 aaaagcgtta aatgtattat ctgattgtga tgttttatta catggtggag atgtcttata
    83641 tcatggacct agaaatgata ttccagaagg atataatccc aaaaaattta ttgagacatt
    83701 aaacaagtta gaaaacattg tgattgtaaa aggaaactgt gatgcagatg ttgaccagat
    83761 ggttatagaa caccctattc agagtcctta tgtcatgagc caatttggtg aaattagaat
    83821 tatattgaat catggttata cagaatcaga agaagaaatt attgacaaag caaagaaaat
    83881 gggtggtgac atattagttt taggacatac tcatgtaaaa aaattataca tggatgataa
    83941 tttaatagta ataaatccag gaagtacttc tatcccaaaa gatggaagcc attctgtcgc
    84001 aattatagat atcataaaaa ctgatgatga ggatgaactt gaacttgata taaacttaat
    84061 tgacatcaat actgggaata taataaatat taatgattag taaattttaa ataaaaacaa
    84121 agtaaacttt aatttattaa attcataata aaaaacaagt aaaccgtttt atttctatct
    84181 caattagaag tttaaggtat tgtacttaaa tttctaattg agatagaatc tggtttactt
    84241 gttttattgt atactatatt gaaatataac ttagtttact tgtttttact atatattatg
    84301 ctaaagtata acttagttta cttattttat tatatattca ttttgattta cacaatatta
    84361 ctgtaatgct aatgcctctg catatggttt actattctta cctccaccaa cttgtacaaa
    84421 tttatcagcc tttacttttt ttataaaact tttctgtgca ctacttaaac ttccacttgc
    84481 aagtactaca ggtgactttg tttttgatgc taatactcca gcagcaagac catcaactaa
    84541 atcagcttct ctaccacttc catcttttgc aaaatacata ttattaacct tacttgattt
    84601 cccataaaac ttttctaaaa cttttgcatt agtatctttt ctatctgttc ctgctagtct
    84661 ttctgcattt actaactgtc cttcaagttt tttacttata ctgtactcac cacctactat
    84721 gtatgtctca gttgagtttt gtgtaataaa attctttgcc tcacttctta tgctatcttt
    84781 acctgtatat attatagctg tattatcact tgccgctgga cttgatattg aagttgcgtc
    84841 tgccagtcca ttataaccat taaccactgc cacttttgag acacctaaat caccagtatc
    84901 atctagctgt ttagtaagaa gtaaagatgt ttcttctcta tctgctccac caattctact
    84961 aactaatact cccatatctt caagaaattc ttttacactt gatgaaatag ctccttcact
    85021 tccaattaaa ataacttctg ctggattaag cctttttatt tcctctgtta cattatatgg
    85081 tatactattt ttattggtaa gtagtattgg tgcatccaat ttacttgcca aaggagttga
    85141 agccaatgca tctggcaatg aatttgagtt aactaaaaac accctttctg aaccattatt
    85201 ccatccactt tgagatattt ttatggctgt atcaaatcta tcttcaccaa taagtgtttc
    85261 ctcctttgga gattttctgc cttgaagata attattcata tctacctctg tattttgatt
    85321 tttactaata gtgtctgcat atacacaact tggcatcata atcccaagtg aaagtacaaa
    85381 cgctattatt tttctagatt taattttcaa tacaattccc ccttttaaat gttaatacct
    85441 attaatatcc atacttttta ttgataccct aaactaaaaa taattatctt ttataaaaat
    85501 aatcataaaa atagctatat catttcagat acaatacaaa cttatactaa gcttgactta
    85561 taaagaatga tatagctatt ataactttaa atgcttaatt tttaaatact ttttaactaa
    85621 actctttcag catatttttc agctattctt acaattaatt tagtagcttt ctccatagaa
    85681 ctaactggta tacactcatt tttcccatgg aagtttaatc ccccagtaaa tatatttgga
    85741 caaggtaatc cattaaaaga taatcttgct ccatcagtac cacctcttac aggaactaaa
    85801 cgtggtttta tatttaattc ctccatagct tctttagcta tatcaactat aaacataact
    85861 ggctcaattt tttctttcat attgtaataa gaatctttta aatccaattc cactctatta
    85921 tcatatttct tatttatttg ttctatattc tctaccataa tagattttct atattcaaat
    85981 ttttctctac aatggtctct aataatataa gacatactta cattctcaac atttccatct
    86041 atagaattta aatgccaaaa tccttcatat ccttctgttg tttctggtct ttcatctgct
    86101 ggaaacattt ctgatatttc agtagctata tgtatagcat ttaccatttt atttttagct
    86161 gaacctggat gaacatttct accatgtata gtaatagttg catttgcagc attaaagttt
    86221 tcacattcaa gttctccaac tattcctcca tctaaagtat atgcatattt tgctccaaat
    86281 ttttcaacat taaataaatc agcacctcta ccaatttctt catctggtgt aaatcctatt
    86341 tttatatctc catgcttaat ttctggatga tttattagat attctattgc agtcactatc
    86401 tcagctatac cagctttatc atcagagcca agtagagttg ttccatcagt gactattaaa
    86461 tcgtcacctt taaattctac caactcagga gaatccttta catacgtaat aacatttaac
    86521 tcttcattta aaactatatc ttttccatca taattttcta ttattcttgg tttaatatct
    86581 tttccactaa catcttcaat tgtatctaaa tgtgatatga atcctatagt atccacacca
    86641 tcagtatttc cttttaaagt agccattata taactatttt catctaaact aacatcatca
    86701 acacccattg tttttagctc ttcaactata tacttagcta aaaccctttg accttctgaa
    86761 gatggacagt tctcacactg agaattagat gttgtatcaa atgatacgta ttttaaaaat
    86821 ctttctacta ctttttgctt cacgtatata ccctctttct taataagatt aatgaaattt
    86881 tttatttact agtgaataaa attttatctt ttaaaaaatt tatcaattat tataattaaa
    86941 aaatatccac cttcttaagt atatcatgca tacataccaa acccaaacaa aaaattactc
    87001 caattattcc ttttacttgg attccaataa aaatcgctgc tagggtagct aatggattta
    87061 gtccaacatt taccgatact agtttaggtt caagtatttc tctaatcaaa gacaagacaa
    87121 aaaatatcac agtcatgctt atagctataa aataattttt tataagaaaa taataaacaa
    87181 ttactggaag atatattgtt attataccta gaaatggaat taaatccatc aaagccccca
    87241 caaatcctac tattagaccg tatttcaatc caaataaagc aaaacttccc catattgcaa
    87301 aaaatgttat agccatgagt attgtatagg ctcttatata tccaacaagt gaaagacctg
    87361 cctctttctt tacgtttttt accttctttc tgacatcaac agtgaacata ttgtaaaaac
    87421 tattttcaat cttatcaagg tcttttgcta taaagtatgt agcaataaac aaagtaatta
    87481 taaatattat aatatatgga atagaagtag ccaatccaag tatactagta agaagatttt
    87541 ttgtaatttg cattacttca ccactgaatt tgtttactaa ttgttctata tcaaagttgg
    87601 ctatttcttg aaatgacttc ataaaatcat ttattttatt taaaaaatac ataatagtat
    87661 tacttatatc ttcaggatta gcagatatat tatttaaaaa tcccattagt tctttcactg
    87721 aatttattac tattattgta gtaactgtac tgactatagc cactgcaaga aaacttagaa
    87781 caagcgtaga gataccttta tttatatgaa acttattttc taacttttga gatataggat
    87841 taatcataag tgctattata ccacctagaa aaaatggagc tatgtatgga aaagctttgt
    87901 aaataaaaat aaataacaat gtatatatac aaaaaaagat agtgttgttc tttaatttat
    87961 ataaaaaatt attttctagt atgctcattt tcaaaatctc ctttcttcta atttatattt
    88021 ttattttgtc catttcatac tagttttatt tgaatataaa taaaaagaag tatatgaata
    88081 taaaagccaa tttttatatt catacacttc taataaattt aagaacatta ttacattatg
    88141 tatatattct tattttttta attctatttt tttctatact ttctatacaa aatcttatat
    88201 tatcgacttc aattacttca ttttcttctg gcaatctgct taggtgtcca attataaaac
    88261 ctcctatgga atcaaactcc tcagattcta gatttacacc aataagttca ttaacatcac
    88321 caattttagt acttccatct acgatatact catcttcttt tataacttgt atttcatcct
    88381 cttcttcatc atattcatcc tctatatctc caacaattac ttctactaaa tcttctatag
    88441 ttaaaagtcc agatgtacca ccatactcat ctacaactat agccatctgg cttttttcaa
    88501 gtttcatttc ttcaagaagt tgtgttatct ttttgaactc atacgtgaaa aaaggctctc
    88561 tcatataatt tttaatatca aatgactcta tttcttcatc agataaaaat ataatatctt
    88621 ttatgttaag tattcctaca atatcatcta tagtttcttc atacacaggc attctactta
    88681 atttttcagt tttaaacacc tgtattatct catcataact atcttccata tctatagcta
    88741 ccatatctat tctttgtacc attgcatttt tggcttgcat atctccaaat tcaaacacat
    88801 tatttatgat ttctctctct tccatttcaa ggacgccttc ttcatgactt acatttacca
    88861 ttgtttttag ttcttcttca gttatgaacg atttagctcc tttatttgtt ataccaaata
    88921 atttaaatat aatatttgta attatattaa atatccacac tattggtctt aatataaata
    88981 taattgcttt tataggtttg gatactaata gagaaacctt ttctgaatta tttgctgcta
    89041 ttgtttttgg agtaatctca ccaaatatta atactaatac tgtcataaca gctgtagcaa
    89101 gtgccactcc tttttctccc attaatccta taaacaaaga tgttgatata gatgttgctg
    89161 ctatatttac gacgttattt ccaaccaaaa tagaacttaa aagcttattt ggattttcta
    89221 ttaatgaact tactagctta gctcctttaa ctccttcatc ttgcatatat ctgattctga
    89281 ttttactcaa tgacattaaa gccgtttcag atgctgagaa aaatgcagat cctataagta
    89341 atactattaa aaatataatc tgaatcaaat tatcgggcga ttccaacact taccacactc
    89401 ctaattacac gtttttatat taatattaat tataaataac tttaatatta gtttttatta
    89461 tatcacaatt acatattatt tggaaatatt agataatata ttcaattaac atatattttc
    89521 taactatatt caatttttac ttttgaacct attccagcct cactagatga aactaatagc
    89581 ttaacaggaa ctctattttt aagttcctcg acatgactta ttatacccac acttagatta
    89641 ttactatgca atctttccaa ggattctata acaatttcca aaagttcact atctaatgaa
    89701 ccaaagcctt catctaaaaa gaaaaattct agtggtgcac ttccctttaa ttgtatttga
    89761 gatgaaagag caagtgctaa tgataaagat gttaaaaatg tctctccacc agatagagta
    89821 tcaatacttc ttctttctcc tccattaaag ttatctctca ttacaaagtt tagtgttgaa
    89881 tcaatttcaa gtgcatatct tccttttgtt attccatcca atctttttga tgcttccaac
    89941 gctatatatt ttaattggtt tgtagaaaca tattctacaa atttatttcc ttgtacacat
    90001 ttatctaatt cttccaataa gtccacattg tgttcaacta ctttaagttg tttattaaaa
    90061 tcatttatct tatctaaaga gtcttttaat gttattaact gattttgatt ggctccaata
    90121 tttttggata tatttcctat ttctactttc aaattataaa tttcatcttt taactgttca
    90181 aaggactcct tctttacact tcttccattt aatttttctt ttgatgattt tattttaaat
    90241 gctaataatt tttgttcttc ttcatgttcc agtatttctt caatcaattt ttttacttca
    90301 tcagcatcta ataaagctct ttttactgca tatatgcttt caaatttatt ttctgccaac
    90361 agtttattta gtgttgattt ttggtcttta tattgttcct tagcagtttt aagtctacca
    90421 tctatattgt gcttttcagc aatgtttttt tcatattcta atctctgctg ttccaatttt
    90481 ttcttgcttg attcctcttg ctctaatatc ttacatatat cttcttcaac actatgtaaa
    90541 agatttttag ctaaatcacc ttttgttatg ttaataactt ctttatactt attatctcta
    90601 ctcaattttt tttctaagta taattctcta gcctttatta actctatctc tatttcatgt
    90661 agcttacttt cattttctct tattttaata tctagagagt ctctattttt taataaattt
    90721 gaatgaccaa tacttagtaa ttctaattcc ttttcattct ctcttatttc ttttactttt
    90781 gacaatagat tggagacttt agtaatcgtc tttaatccta tatactcttg tttaagtttt
    90841 ttacatttat tttctaaacc ttctatttct atgtttaaat ctcttgttaa tttcttataa
    90901 ttattcaagc tctctcttat ttttaattct tctttttcaa ttttattttt ttcttctttg
    90961 gctaatgtta ctttattttc ggtactctct ttttctttct cccactcctg aatattagac
    91021 ttcaataatg caagctttct ttgctcctca tcaagttttt ttaataattg actagatgga
    91081 atatccccca gttttccttt tacatcttca agttctttag tcttcatttt ttctatagat
    91141 aaatacccac ttaatttagc atttaattcc tctatattgt ttcttatact tattttttct
    91201 ttttctaatt tctccagctt ttctttgaca aaggatatat tttcatcata cttagttata
    91261 ttatgatttt catgatgttt tgacccacaa actggacaag gcatattttc ttttaattca
    91321 cgtctaagtt cagaggccaa atttaaatac tttagttgtt ctaattcttt ttctaggtca
    91381 tctctattct ttctattatt ttcaagtttt tcatttagta aatttacttc cctttcagta
    91441 ttaaacttac tttcaagtat tatctttaat tcatcttgta tactactttt tttgatttca
    91501 ttttctttag tattatctgc cttatttctt aactcagtaa catattcaga ttttaaaagt
    91561 aaatctgcac tctttccagg acatttttta agaagaacat ccaagtgaag agataaattt
    91621 tctaaattac gatttacatc attcttatct ttatcaatat atctaacttt taagtttata
    91681 tcttctgtct ctttgagtat ttcttctagt ttatttatct tttgattttt ttcttccaat
    91741 acattattgt aatctttctc gtattcatat gctagaaata ttttttgttt taattctgca
    91801 cttatattta ctttattaat ctttccttca acttctttta tagatttagt aactgcatct
    91861 tttctggact ctgacatctg ctttactttt tctaattcaa ctttagtttt atttaagtta
    91921 atcccacttt cttttagctc ttttaactct ttatctaata aaactaattc ttcttctaat
    91981 tttattgcct gttgtaatct tattttttct tcacttaatt taggaacttc ttcattctta
    92041 attttgttta ttttttcata tctatttttt ataacttcaa gttcctgatt taatattact
    92101 aatttctttt ctaaattact tactgtaaag ctatcttcat ctatcttttt ttctaaattt
    92161 tgaactgaac ctatgtatgg gtctaccttt ttagcattac tatcattttc tacaagagca
    92221 atcttttctt ttatctcacc atttttcaaa tcaagctcat tttttctaag ttcatttttt
    92281 tctagcttta attgttcttc atatactgtt ttactttctt cgtaagaatt ttgagctagg
    92341 tctaaagcat tattcttatc tttttccaaa ttttttaact ctattaattc ttgatttata
    92401 ttgttgtata cttcttctgt aattccatca tattgactta attttgattt taaatctttc
    92461 aaactttgta actgtaaatt ttttctcttt ttcacttttt ctccaagact tcttccatat
    92521 ttctcaagat taaaaattct ctctaacata tctcttctat ctgcacgtga taatcttaga
    92581 aattcattaa atttgtcttg tggtaaaact actgacctag taaaatcatt tgcagttagt
    92641 cctacaactt gagctacttt ttcatttact tccacaactt tatcagccaa aacattttgg
    92701 gtattgtcat ttaatacttc tattaatctg gcattagagg tttttgtccc tgttttactt
    92761 ctagcaatgg ttctatctac aatgtatctt cttctagtgt ttttacttcc tatctcaaac
    92821 tcatacgata taattgcctt atcgcacaca ctgtttatat attcttttgt atttctggat
    92881 atatttccat acatagcaat agttattgca tctaagattg tagattttcc acttccagta
    92941 gttccaaata tcccaaacaa acctctttca attaattttt caaagtctat aacttgttta
    93001 tcaatatagc tattgagccc tgtaagttct aatctaattg gtctcatctg ctgattcacc
    93061 ttcttcactt attatatcta gaaataaatc cataagttct ccttttggct ctacaccttt
    93121 actaaaagaa taaaattctc taaataactc tgccatagac ttttctttta tatctacact
    93181 ttcttgttca taacaagatg ttattattgg ctttatttct attatgtctt ttaatagttc
    93241 tttcattttt ttaatttcat tctgtgatat tacctcttca gtatttattt caaagtatga
    93301 ccaaatctct ttatcttgat tttgttcaca tatatctagt gcttcttcta ttccattaca
    93361 tttaaatact tctataggtt tataattatt aaaatataca tcttcaatta ttggtttttc
    93421 accagctttt atatccacta tgtatgcccc tttggtatat gctctttcat ccttgctata
    93481 ttgaagtgga gagccagaat agtatgcatt taaacgttca gaagcttttt gttgtttgtg
    93541 taaatgacct aatgcagtat attgagcctt ttctggcaag tcttttcttt caaccaaaaa
    93601 acttccacct agttgtatag gtctttctga ttcagtactc tctccaccta ttacaaatat
    93661 atgtgataca gctatattta tagtatcact tctaaaattt tcttctaaac ttctaaatat
    93721 atctcctacc ttttcagaat aatttttttg tttctcaaaa tcatcttcac ttgaaaaaac
    93781 ttcatttaat cttttttcac ttggataagg taatgtagca accacaacat tttctccatt
    93841 tatattcagt tttgtacatc cctgagttgc acatgttatt tcaaaccctt tatacttagc
    93901 ttctatcgta gcacttaatg gataaccata tataagtatg ccttgttcat gtgctagagg
    93961 cgttattgca gaaagtctct ctggattatc atgatttcct gaaattatta atacacacct
    94021 ctgaccatta ttagcaagtc ttgatacagt ctgataaaat agtttttctg cttgtgctgg
    94081 aggattagaa gtatcatata catctccagc aattataacc atatctattt catttgattc
    94141 tactattttt ataaattcct cacaaaactt tgcttgttcc tcaattctag aatggccttc
    94201 tagggatttc cctagatgcc aatctgatgt atgaataaat ctcattgttt ccccttcctc
    94261 tatcttttag gtttaattta tatataaact aataacaaac agcttcatca actccaaata
    94321 aatatataca tttttctttt accgacttac cagttaaagt ttcaatgata tctgcataca
    94381 aatccaactg ttttttatat ttctctatta tttgatttat attttcttca tttacaaaat
    94441 ctgttttata atccaccaaa actatttgat tatcttcttc aaaataagca tcaactatcc
    94501 ctcttaacat gacactttct tcatcataaa gttttttatc atcattgttt ataagctttt
    94561 cgtaaatata tatgtctttc atatttactt gtgcgtaaat tgatttttct ctatttataa
    94621 gttcagcatt caacattctt tttcctatgt tagattcaaa aaacttatat attttatatg
    94681 gatttactat actagcctgt ttttctgtta ttataccttt tgaaacaaaa cctcttattt
    94741 gtgattttat atcatttaca ttacttacat tttttaagtc taaaacctcc ataactaaat
    94801 gaactattgt acctctttct gctccactta ttttatctct ttcttcttca ttttgaataa
    94861 atagaggctt ttttaatatt actttttgtt caaatatagt atttattaac tcttcttcat
    94921 aattattttg tatctttttt atttctgtaa cagatatagt agcaggtttt cttgtgctaa
    94981 attcatatgg atatatatag tttaatttct cttctatttc attgtaataa tcactgtcag
    95041 gactatctac atctattttt tcaagaattt tttcaatact ttctttctct tcattattct
    95101 tcttttccac taaaatatca ttcttatccc acaactttcc ataccatttt gaattatgtt
    95161 caacactaaa aactgcgtct aatcctactt catctaataa attagataaa tccctatgtt
    95221 ttaatacaca aggcattatc caatctaaaa aatttttacc ttttaatatc tcatattgtg
    95281 atattgtatc tgaattttca accccatttg accatctctt tatactatct tgtatatttc
    95341 tagtagaacc tgttataatc aatttttctt tagcccttgt aaatgcaaca tataaaactc
    95401 tcatctcttc cgataaattt tctatattta ttttgctttt taacgcttct ttagctatac
    95461 ttggaaaaga aatccgtctc tcataatcta caaactgagg tccataccct aaattgtgat
    95521 gatataaaat actcttttta aaatcttgag tattaaaatt tttacccatt gcagagcata
    95581 taactactgg aaattctaga cctttacttt tatgaatact cattattcta acaacatttg
    95641 cattctcacc aagtgttttt gcacttccca tatcagaact agactttttt aatttctcta
    95701 taaaatttac aaagttgaat attcctttaa gactagtctc ttcaaattgt tttgctctct
    95761 caaacaatac ttttaaattt gcttgtcttt gacttccacc tggtaatgct ccaacataag
    95821 catagtatcc agtccttgtg tacaaatacc atataaattc atctgtactc atgtacattg
    95881 acttttcttt aaattccttt aacttaatta aaaaatcttt acttttgttt atgcactctt
    95941 cacttggtat aaattcagac tcattttcat tctgagaatc tttaaactca ttgtactctg
    96001 ctgtactttt taaaacctca taaaaaattt tatctttact ctgaactcta atatctatca
    96061 aatcctctgg ggtaaatcca aatataggtg attttaatac agatataaga ggtatatctt
    96121 gcattggatt atctattatt tgaagtaatg acaatattgt ttttatttca atcgtatcaa
    96181 aataccccac tccgacatca gcatatgttg gtatatccat attcatcaac tcatctgcaa
    96241 acactggagc ccatgcagat gtagctctta aaagaataac tatatctcta aattccacag
    96301 gtctatatcc acctattcct ttatcataga ccttttgaag ttttccctct tcattaactt
    96361 tcattaaatc tttgataatc tttccaacca ttctagcttc aagttggata ttatctaatt
    96421 tttcttcttc ctctatttca ctttctttgt tattagtcct atcgtcttta tcgtttataa
    96481 tatcatcatc aagtttatta tctttttgta ttagatgtat ctctgttgct ccaccaataa
    96541 tagatttctc gtctgtatcc atctcaaaat ttgcacctaa atttagtctt tctttttctg
    96601 tatattcaat ctctcctata ttctcattca ttatattttc aaatatataa tttacagcat
    96661 ctacaacttc ttctctactt ctaaagtttt tataaagcat tatttttcta tgggaacttc
    96721 cctttttatc attatagtta ttatattttt gcaaaaataa ttctggcttt gcttgtctaa
    96781 atctatatat actctgtttt acatcaccaa ccataaatct atttggagtt tctgtattgg
    96841 ccacagcttt aagcaggact tcctgcacta aattactatc ctgatattca tctataaata
    96901 tttcataaaa ctcattccta tatccaactg ctatatcaga aggtacaata ttcccttttt
    96961 catctacatc agtaagtata tttaaggcaa aatgctctat atcattaaaa tctattattc
    97021 ctttttctct tttcttatta ctatattcct cttcaaatct cagtacaata ttagatattg
    97081 gtttaactat gttataaaga tattttattt cttctctaat agaatcatta tctttattga
    97141 atgtagcact tactatactt tctaaagact tcttagtctt atctcttatg gtttttgcct
    97201 tttcttttga ttcttttata tacgagggag catcttttga aattcttttt actcctttta
    97261 cataattttc aaaggacata cttgacatct ttttatatgt ctcatcccaa gacttattac
    97321 atgcttgtga aatgtcgact atttttttat attcagcaga taacttttct gcaaaagttt
    97381 ctaattcttc tattgattcc acttctttta atgccctttc catgtttaga caaagaccat
    97441 taatctctat ttttacagtg tctaatatag ctctagccca aatagactgt gaaaaatcaa
    97501 aattttcatc aatattaaat ctttctgctg agtcaatcaa ccatttttta ggttcaggag
    97561 aagccattgc aaatgaatat attcccaaaa taatatcttg tacttcttta tctcctcctc
    97621 tttctgcata actttcaact aaatttaaaa aaccctcatc tctttcttca tataaatctt
    97681 caaatacttc ctctattgct tcttgtttca aaatagcaca ttcagtttgg tctcctattc
    97741 tgaaattagg gtctaagctt attctatgaa agtttgattt tataacatcc aaacagaatg
    97801 agtgtattgt tgtaatacta gatttattta ataaaacaag ttgattttgt aaatgtttat
    97861 tttctgggtt ttcatctaag gcttttccta tggcatctcc tatcctctct ctcatttctg
    97921 atgcagcagc attagtaaat gtaacaacta ataacttatc tatatcaatt ggattttctc
    97981 tacttgttat catttgaatt atacgctcaa ctagcacagc tgtttttcct gaaccagcag
    98041 cagctgcaac caatagatta cattctctac tttctatgac ctctagttgc tcttttgtcc
    98101 atttaggaga actcactaat taacatctcc tttcatcatt tttattattt cttcattgct
    98161 cttattattt aaatttttat atttattatc tttcatagtt gaatcaaatt gacatatagc
    98221 agaataatca caaaagtcac atgatgttcc atctttatgt ttatatggag ctatacatat
    98281 ttctccactt aacatgtctt cacacaaatc ctttatagca tgctttacat attttctgag
    98341 tagtttaaaa tcctcatagc ttattgctga agtacttttg cctacatttc catctttagt
    98401 aagacctact ggtattacta aagagttttt tctttctcca tctattaatg atttatccat
    98461 ctttttaact atgtgagagt cttttactac aagccccttc attctaagtt cttttaatat
    98521 tgcttcttgt atttctacat catctttatc ttcattaaat tttgctattg ggttatttat
    98581 cctacaatat agtattgcag ctggatttat atttatatct ttatcctttg cactttcaag
    98641 gattgcatct aaatacacaa gtaattgtaa ttgtagacca taatatattt ctgttagact
    98701 tatggactta ttgcctgact tataatctac tattcttata tatttatttt ctccttcttc
    98761 aaattcatca actctatcta tttgtccaat caaacttact tcttgtccat tttctaacac
    98821 tatttttata gggggatatt ttccattgtc accaaattta acttcataat ctattggttc
    98881 aaatgaacct tgttttattt gctgactaat tatagttata gcagttgtca acatattctt
    98941 taatctatat gcaaggtatt tatacctctc agaactattt aatatatatc ctggtatctt
    99001 taaaattatt tcatcaacta ttatacctat ctttaattct atatattttt catcaatacc
    99061 tctccaagat aaattatctt gtaaaagttc ttttgaaaac ctatctaaaa tattatgaat
    99121 aaaagttcct aaatctggtg gtgtaaatga atactcttta cgctttcttg cttttagacc
    99181 atattgtata aaataagcaa atggacattc agcatatttt tcaagcctag atatactaag
    99241 agaattactt ttatacaatg accttatttt tttctcttca atcctatgaa cttgattagt
    99301 ataactaaga ccttttataa ctttttttgt tatagaacta tagatttcat cttttaaata
    99361 gtacctatat atatctaacc aaatactatt aatctcttct ttattgtaac catcactgtc
    99421 ataatttttt attacattta taagttcatt aaatgtagga gatttaaccg ttattttttt
    99481 aagtatatct tcatcagtgc ttttattttc ttctactaaa taacttttat tttctatatt
    99541 tggaaatatc ttcttaagtc ttgatataat tattgatggt ctaagtgttt taccctcatg
    99601 gtccgatatt ggatatgtta tggttaaatt cttagatgtc gaagtaaggg ctttatatac
    99661 aagaaactgt tcttcaaaac ttcttgtctg actatcaata tcgacttcga ttcctttgtt
    99721 tccaagactt tctctatcat tatcacttaa tattccacta tcctttgtaa tcagaggaaa
    99781 tactccatca gtagttccaa ctagatataa atatttggta tctggatttt tcattctatc
    99841 aacactactt acaagtactt ggtctatact aggaggaact aaccctaatt catattcatc
    99901 aaaacctaag gttattaatt ttataaattt ttctaaagaa attatttcat cacccataag
    99961 ttccaccatt tggtctaata tatccaccac tatgtcccaa acttgtgaat attgatttgc
   100021 aacatcaagt tctcctttat ccttaaaatt tactattaaa ctttctatag tttctggcat
   100081 atttatatct aataaaaatt catatatata cctacaaatt tcttttactc tattttttcc
   100141 ttttaatttt tcttgtaaag taactattgg ctctagtact ctatttttta tttcatttat
   100201 tttatctttt aattccagtt caaattcact ttcttcacct gaaagacttt gtgttattct
   100261 ataatcccat ttttcatcaa accatttctt acctttaatc ccattagcca agacataatt
   100321 ttctaatacg tttatatcat cattatcaat tcctataagt ccacttttta aatacctaaa
   100381 catagtttca tacccatatc gtctattctt catttctaaa gctgaaataa ttaaaataac
   100441 tattggatta ctttttgcct ctctcttctt atctataaag tttggtatat tatattcatt
   100501 aaatatagag tgtactaaaa aatcatatct atttaaatct cttgtagcaa tagttatatc
   100561 cctatacctg acattcttct ctctaactaa atgtacaatt tctctggcta tttcttccac
   100621 ttctgaatat aaattgttaa actcttttat ctttatattt tcagtttgct ttgaatatat
   100681 tttatatgga taagcattat aaaatctttc taggtgctgt aattccttaa ccttttcaaa
   100741 tctttttata acacctgtat ttaaatttac ttgtggcagt atttttattc cttcttcgtt
   100801 gcacaattga gtcaattttg aataagtaaa tttcgttcta gaaaacatat cagctttact
   100861 gtacccagta tagttgacat catctacagt caaagagata ttaacacttt tagatttatt
   100921 taatatactc tttatgacat tgtactgatt tggtgtaaaa cctgtaaatt catctatata
   100981 aacgcaagct ccatctaaat aactgcttaa ttcaatttta ctcgccaatg aagttaacat
   101041 atcttgagca tccacataat tttcatgcaa tttcccttca aaagagttat atattttact
   101101 tatatctttt aattttaaac ttaaagtttc attatccaat tctccagata tattttctaa
   101161 catttcaggg cttatattgt attgtttcat ttctgatatc atctctgtaa ttgagcttac
   101221 aaaaccagcc tgagattttg attttgaaaa cacatttaat tcttcactta catcttcaat
   101281 agccctatac accatcattg cttttccact agaatttata tttacatctg ttaatcctcc
   101341 tacttgtgaa aaaactatat tacttagtgt cttaaagcta agcatcctaa ctcttaaata
   101401 cttatctttt tcttttccta aaaatagttt acttactcta ttttcagcct caaatgtgta
   101461 ctgttctgga actaaaagta taattgatgt cgtttcattt ttttgagctt cttttttaat
   101521 ctcatctagt atataggtgg attttccact tccacttcta cctaatacaa acctaagtcc
   101581 cataaatttc cgcctccaaa atactataat ctatttcttt gccattacat aacttattaa
   101641 attcacaata cttgcaatgc tttttatttc tatagcacat acgttcttct ttattatata
   101701 ccttttctat atcattgtat agattgtctt cgtatgtatg ttcttcataa ttagtgtttt
   101761 ttatcatact tatataattt tgaattttat ttctatttgt ttcatgtttt tcttcattat
   101821 ataaaatggt aattggtaag tcatcaaatt caggctgata atatctcata tttatatctt
   101881 taacatttat gtccattttt aaaactttag gtattacttc ttttgctaaa aacatataaa
   101941 caatagtttg tattctattt tctacgtgtt tatagtcaat ctttttagac tcggttttcc
   102001 aatcccatat atctatattg ttatttccaa ttacaactaa atcatacttt gcctgtattg
   102061 tatctccatt taaggacatc cttacttcat attctggcaa atacgttttt cctttttcaa
   102121 taggaacaac tttttttatg ttttccatcc actttaaaaa ctttttacta tttttattgt
   102181 cctcattaaa atagattcca agaggtatat tgctaaaata tctttcacaa atcaaatgaa
   102241 aatctcttcc tgtttttaaa gtttcataat actctctact accaacatca tcatttttcc
   102301 aatttattct atcaatatat ttatatttaa atttcagtgg acatgattta tatgtgttaa
   102361 ttgaattttg actataagaa aaatatttta atttatcgtt cactcatatc acttctctct
   102421 taactttatt ttttaatagt tacttactgt acatattgtt ctatcccatt ttaaaagtat
   102481 ttcaagcaat agtttaataa cttattatac attaatttga ccttttttta ataatatgtc
   102541 gattaagtct gcctaaatat atacatggtt tttgctcttt tctcttatta cctatatcac
   102601 tttcatctct ataagcactt cctgaaagta ctaacatctc ctttgctcta gtaattccta
   102661 catataaaag tctaatcttt tcatttatag aatcaatctt cgttttatga gcataatctg
   102721 ttgaaatact tcctttcaat atagcttcga cttctgattt aataattgcc ataggatttt
   102781 tatatttttc ttttaaatac catttatcac tctggaactt ttgattaata ttgtcaggga
   102841 aattatattc aacaagacct agtaaaaata cacaatccca ctccatcccc ttcgacttat
   102901 ggtagttaca tattgttata ctaccaggct ctggctcata tccatttatc tcatatacca
   102961 catctattat atgattaaat accttattct ttacatcaaa caataagtta tatacatctt
   103021 ctaaatccat atttatattt tctgatgcta gatattttat ataaaaggat atataatcaa
   103081 gtacagcttt atcttctttt tctaaattaa gttttttccc aataaacaaa actaagaggt
   103141 ctaaccttat tattggatat tctaatatct gctttataat atttattcct cttttaaaat
   103201 ttaaatatat atcactttct tcattaaatt ctattaaatc attatctaac ttactaaatt
   103261 caaaatcata aataatttct tcggtagaat agttttttaa tttttctaaa aaatacttta
   103321 attcttcttc attatcagta tctataaaaa ctttatcaag tacaactatt aacttttcta
   103381 tatcatcaca atgtaaaata aagtcaataa tagatgctat gttatttata actctccttt
   103441 tactcaaaga atttggccct aattcttcaa agactagatt gttctctcta agttctttag
   103501 caacttgtgt cacttgctca ttaaatggaa ccaagatacc tatactttta tctggatatt
   103561 tattttttat acccttaacg tatctagcag tttgttctat ttcaaatttc caactatcat
   103621 accactttat atttatatta taatgttctg gattaggatt ttctttatat cccattccat
   103681 ttggcacagt ttttatttgc atatcttcaa gagcatgtct acactcttcc tgtctaaatt
   103741 cctttgtaac atattccaca agagtgtttg ctaaatcaag tatatctttt gaacttcgat
   103801 ttgacatatc catcctataa cagaaatctg cactatttat aaattcttta aaaaacttag
   103861 ggtctgatga tgaaaatgtt cctgttatac tctgatttat atctccaacc ctaactaagt
   103921 ttctattttc actagatata atttttatta tattaccttg aatttcattt gagtcctgac
   103981 attcgtcttc aaatatatat ttgtatctag tttgaaattt ctttctaagc ccttcgtcta
   104041 agcttaaagt tttttctgct aaaattaata tatcatcata gtctagtaat ccattttgct
   104101 tcaatttcct atcatataat ttatatattg gtaaaataat tttaagcatt cctttttgtc
   104161 ctcttgacaa tatttcttca agtttatctg gagaaattcc cttatactta agttcactta
   104221 ttgcatttcc cgcaaattca aaaaaacctc tttcccaagc ttcaagagtt atttctttcc
   104281 aacgttcatc tttttgctcc tttaaaaacc atctaaaagc tctttctcca ccttcaaatc
   104341 taaatctact tatacattca tttaatataa tatttttttg caaatcgtca gctatattaa
   104401 aatcctcact taacattaca acttctggct tttcctttat tatttttaca gccaaactgt
   104461 gtatagtcat tacttcatac gaattagtat catctatttt atgctcttca agaatctttc
   104521 ttattctacc tttaaaatta tttacagcac tattcatata cgtaagaact aatattttac
   104581 cacccttgtg cttctgttca agtaatagtt tagccactaa atttgttatt ataaatgttt
   104641 ttccagcacc tggtactgct ggtactgcca tagtaccatt atcgtaattt attattggta
   104701 tttggtcttc tctataattt atattaatca taattttcat ctcctttatg tgagattttt
   104761 aaaagtatac tatataatat actctcttgg atataaccat taatcgcata ttcactttta
   104821 tatgcataga ttttctttgc atttaatagc aaattataga ctgtattgta tagataatat
   104881 ttcttatagt attcttccat ttcatttgta taaatttttt tttcttcaaa agattttcta
   104941 agtacaatta aattacttat atctttttct attttcatat tccaagcatt acttcctata
   105001 tctacccata tttgtatact tctatctata tttgatgcta tatatgaata aggagtagtt
   105061 attactattt tgtctttgga tttcaattct tctatatcga caacagagta ataatcgttt
   105121 attgcagtct ttaaagcttc tataaatatc tcttcttttt tcattccaag taaacttaaa
   105181 ctttcactaa aagactcact ttcggctatt atctttttac ataacccaac atttttttta
   105241 ccatctttta aacttagcat tttatctata taaaactgaa ttaaaaattc atgtattttt
   105301 aaatcactct tctttttttc ttcaatatac tgtaaaatat cacgatactg actatgttca
   105361 tccatattat caatacttaa atgtcttgtt tcattaaaaa tcttaaatgc ttttatccta
   105421 tttatttcta aaagtgtttc taaaaagctt aagtattcat catcctttat aaaatctaaa
   105481 tatccataga acatgcatgt agccactacc aatgcatttc catatggata atctacagct
   105541 tttttatctt tcttaatatt aaaaacatct atattttttt ctatcaaaga atctctaatt
   105601 tgatactcca atatactatt gtttatagga gatataattg ctatatctct tagagataca
   105661 ccttcttcta taagagatat gattttttca cttattaagt ctaacatttc attgtataat
   105721 tgacttgatt gatttaattt tatagttgca ggtaataagt ataaatcttc tattcctatc
   105781 tccttccttt taatattttc ttctttggac ttaatttttg atattatctt ctcatttata
   105841 tagtccatat ccacattatt aaatacagaa taatccctac tatagtcaaa atatatataa
   105901 ctttgtaatg tattatctaa tgcttctgtt ataaaatcaa cttctgcatt acttgagctt
   105961 tcaaggctat ctactattat atatctaact tctttaaata agctttttac ataaaaatca
   106021 tcattaagta gatactgatt gtataaatat acacttaatg aattatctaa aatggaattt
   106081 gatagtaatg aatttatata atatgatata atttcatcca tctgagtgta tgaaaatcta
   106141 tatatactat ctttattttt ctttgatgaa tatatttttt ctccaataaa atcaaaatca
   106201 attaaattaa atgctgactt atttatatta gtcattatac tctttgctat tgatttattt
   106261 gttccagtaa tgtcttcaaa atatccttct tgtatccttt tttccttaac tttttgcact
   106321 attaaatatt cacttaaact atttgatata aaggttggag atacagcctt tttatttatt
   106381 tcatcacaat tttctattat tagtggccaa tatttcaata attctttctt cacaaaactt
   106441 atatatgttg ttattttcag ttcttcacta taatttaatc ttaaagacct ttcatattgt
   106501 atctttgtgt tgttgtttgg tactaataaa agaatacttc ttgaattatt cttagtttta
   106561 tctaatattt ctctatattt atctaaaggt tcatttccac attcttttaa actacttttg
   106621 tcaattaaat attccacata atcaccttcc tcaattaaat taagtgtatt ttatctaatt
   106681 atatcatatt gtgtaattta caaaatacaa tcaaattatt gcatttaatt acaaaaaaag
   106741 actatatata cattcttgca ttcatatatg caaatgtaca tacagtctct actattgata
   106801 cacttatatt tcattttata actttagtat aaatttacat taagttttta aataattttt
   106861 atttctattt attttaatga atcttctatt cctttgccta tttgtatacc catttctttt
   106921 actttcgcag gtgagtttat taaactcaca tctttctcat tatccaaaaa tgcacattct
   106981 acaagtacag ctggtatatt attagttctt aaaacgtata aataatcttt tgtagagtca
   107041 ctaggaagta ctcttgtttt tatgcctctg tttgtaagtt taaatttctc taaaattcta
   107101 tttaatatgt ttgtagctac agtcttagta gttcctccat ttttatcttt aaacttataa
   107161 aagacttcta ctccatgacc ttttctatta ttatcaccat tgtaatgtat acttgtaaat
   107221 aagtctggtt taagtgaatt agataaagca gttctacttc caagagataa ggttttatct
   107281 gtatctctag tcataattac atttatatcc tttgaacgta aatattcagt agttgcaagt
   107341 gaagtattta aattgtaatc tttttcaatc attcctccaa atgaatttcc aggtgctgaa
   107401 ccaccatgcc ctgggtcaat cattactgtc ttagcaccat tattacttcc tgggtctgct
   107461 ggagttgtat tatgtttaga taatgatgat gctatagaac tcattacctt agaagtcaat
   107521 cctccaccta ttttatatac cttattagct gatttagttt ctaaattcgt tttatgatat
   107581 gcagatacat acgtctttgg tgttataagt attggcgatt ttaaactagc agccaatgga
   107641 cctgctgcta aagcatcaac aagtacatct gatttagcta ctaaaatagc ttctaactca
   107701 tcatctgtat agaatttttt tattacattt gcatttgttt catgtctatc tgctccatac
   107761 accctattat tagtaacgtt atccttagtt attccattta ccttgtttat aacatttgtt
   107821 gatatcattt gaggaccacc tataaaataa gcattttgta aatcctcatt ctctagccat
   107881 ttagacgtat tatctgtaat actatcttta tcagttagta ttattggttg cttatcttga
   107941 cctgcttttg ctgctatcgt aagtgcatct acttctccac cattagcatt tgttatgtat
   108001 actttttcca catcatgatt tttatctatt tcctttgcta tcaataaaga tgtctcatat
   108061 ctattagagc catttagacg tgtttgagta gcatttatag ttgatttaat ctgattagca
   108121 gtagttttag aaataga
//
LOCUS       DBGJFK010000003       107384 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.003, whole genome shotgun sequence.
ACCESSION   DBGJFK010000003 DBGJFK010000000
VERSION     DBGJFK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 107384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107384
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.003"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            373..1590
                     /gene="ilvA"
                     /locus_tag="ACOIAP_000227"
     CDS             373..1590
                     /gene="ilvA"
                     /locus_tag="ACOIAP_000227"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HGZ2637151.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKSYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDRYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKVVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1685..2065
                     /locus_tag="ACOIAP_000228"
     CDS             1685..2065
                     /locus_tag="ACOIAP_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGZ2637152.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2351..2833
                     /locus_tag="ACOIAP_000229"
     CDS             2351..2833
                     /locus_tag="ACOIAP_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGZ2637153.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNCINIEKVNDSVFSKRLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVNLQGDGFKNEVSQGD
                     NVKKGSPIISFEREKINSQGIDCTIIMVVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2854..3669
                     /locus_tag="ACOIAP_000230"
     CDS             2854..3669
                     /locus_tag="ACOIAP_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGZ2637154.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKANEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEVIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSINLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNIYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3722..5272
                     /locus_tag="ACOIAP_000231"
     CDS             3722..5272
                     /locus_tag="ACOIAP_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGZ2637155.1"
                     /translation="MKDKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     FPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQIAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGVDTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEGQSKQLNLDTGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEIY"
     gene            5319..6671
                     /locus_tag="ACOIAP_000232"
     CDS             5319..6671
                     /locus_tag="ACOIAP_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HGZ2637156.1"
                     /translation="MVITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKGYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLENFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6847..7353
                     /locus_tag="ACOIAP_000233"
     CDS             6847..7353
                     /locus_tag="ACOIAP_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGZ2637157.1"
                     /translation="MITNNLEADTHSHCMLQMFLGIEENIEIIVNEKLVKCNCIVVDK
                     NISHSFSARKKVYYSAIIEPTSIYAEQLTSKMSDFGYWICDNDGLEKLRQQGTFLIYN
                     SSKEQYLRFMEMLNNYLNIPITLKNYDDRITELLNLLRTCNCDNHTISSFADKVSLSA
                     SRLSHLFK"
     gene            7363..7560
                     /locus_tag="ACOIAP_000234"
     CDS             7363..7560
                     /locus_tag="ACOIAP_000234"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637158.1"
                     /translation="MPLKSYILFHQMECAFRELLSGKNVTETSMTAGFDTPSHFAGTV
                     KRMMGMPVSLSLKDSEFLKVY"
     gene            7607..8326
                     /locus_tag="ACOIAP_000235"
     CDS             7607..8326
                     /locus_tag="ACOIAP_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase family protein"
                     /protein_id="HGZ2637159.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKKWLELDDFYKIKSIYEFV
                     QNDILFGYNASDILSATQVLNDGMGQCNTKATLLMALLRAVNILCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFSNYGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8450..9850)
                     /locus_tag="ACOIAP_000236"
     CDS             complement(8450..9850)
                     /locus_tag="ACOIAP_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HGZ2637160.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLVARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLLLSPIAILDVILSFILLKNVGETQKLKLDIPSIILSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPIFIGIISLIFFTLRQLKSREPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPVAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLLHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINSTLRQISGAIGSAVLITIMTSATKKAHMSSAILSNIHGIDVAFSIAATLAFVG
                     LIVSICFIKRHQIIRS"
     gene            complement(9854..10744)
                     /locus_tag="ACOIAP_000237"
     CDS             complement(9854..10744)
                     /locus_tag="ACOIAP_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2637161.1"
                     /translation="MTEKQRLIITIAQKIFDQKGFQNTSISDIVKECKMSKATFYKHF
                     ETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWENIFSRTTINTYI
                     RENFSEVQRKTTSKLQTKSRANLLNEYKLSLFDNYGDKIENIIFDLVFLLDALIHQFI
                     YIIHVQKREINVYFVAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEAYFSLYNKS
                     LFFKTIQDIEELIKTDTSLLENSKLLEATKKLYVEGKNQQYDSLIMDSMIAYLEKEDT
                     LRPKVLLLNSIKNQLKKETL"
     gene            11024..11671
                     /locus_tag="ACOIAP_000238"
     CDS             11024..11671
                     /locus_tag="ACOIAP_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGZ2637162.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARNAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGNDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKEHITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11996..14635
                     /locus_tag="ACOIAP_000239"
     CDS             11996..14635
                     /locus_tag="ACOIAP_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGZ2637163.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQTLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGSVVVYGRGSFIVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMVGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEDDFVPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     DGDLALTGKELDALSEEELYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSILFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLRAVAIRGCIIGIVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14693..15796)
                     /locus_tag="ACOIAP_000240"
     CDS             complement(14693..15796)
                     /locus_tag="ACOIAP_000240"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HGZ2637164.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFLTLDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVNPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQVIDNIE"
     gene            16157..16978
                     /locus_tag="ACOIAP_000241"
     CDS             16157..16978
                     /locus_tag="ACOIAP_000241"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGZ2637165.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKNGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTTTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIIRDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    17058..17268
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17355..18671
                     /gene="argH"
                     /locus_tag="ACOIAP_000242"
     CDS             17355..18671
                     /gene="argH"
                     /locus_tag="ACOIAP_000242"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGZ2637166.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCILYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLALDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELYKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18918..19256
                     /locus_tag="ACOIAP_000243"
     CDS             18918..19256
                     /locus_tag="ACOIAP_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HGZ2637167.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19381..20670)
                     /locus_tag="ACOIAP_000244"
     CDS             complement(19381..20670)
                     /locus_tag="ACOIAP_000244"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGZ2637168.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPSIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKNLPQIDGSSMYLKEGE
                     SFTVKQLLNALLVHSANDAAFVLARYVGGGDVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELVYEPKNSYRIFLEKNESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNIYNNGKLENSIDLIAKNNLDSSIPFLTGNNILMT
                     FVKIIAGILVLLVLFIITSNIKRKKRKKARSKRNMKK"
     gene            20750..21454
                     /locus_tag="ACOIAP_000245"
     CDS             20750..21454
                     /locus_tag="ACOIAP_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGZ2637169.1"
                     /translation="MKKKVKFISFFILFILIISSIIVYKSLIFKDDIYVVSKKVSSNE
                     KTHAVEAEIKNEDNSHNKATKDIDKNFQNNKITIYISGAVNRPGIVTIEPDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEAISVTSNDDSNKSNQKNESRSEPK
                     NKSNKNISNKSKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21546..22592
                     /gene="selD"
                     /locus_tag="ACOIAP_000246"
     CDS             21546..22592
                     /gene="selD"
                     /locus_tag="ACOIAP_000246"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001887 - selenium compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:21594..21596,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HGZ2637170.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFAKVKESGALLVGGHTVDDKEPKYGLSVSGIVNPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFDK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEIVGNVEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22643..24022
                     /gene="selA"
                     /locus_tag="ACOIAP_000247"
     CDS             22643..24022
                     /gene="selA"
                     /locus_tag="ACOIAP_000247"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004125 - L-seryl-tRNA(Sec) selenium
                     transferase activity [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HGZ2637171.1"
                     /translation="MLPSVDEVLSDNRIVEIINEYPRSLVLESVREVIDLKRQFILRL
                     KEDISNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLGRSLLSEDIKDE
                     LWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNAAAVLLVLSTMA
                     KGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYKEAITEDTNVLM
                     KVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKYGLSYEPTVLDS
                     IRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDKLTICALEATLR
                     MYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINIEDGFSQVGGGS
                     MPLETISTKVIAITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDVRTIFDDEFDVI
                     VDELRKAFN"
     gene            24136..26019
                     /gene="selB"
                     /locus_tag="ACOIAP_000248"
     CDS             24136..26019
                     /gene="selB"
                     /locus_tag="ACOIAP_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HGZ2637172.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNESSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIENGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKKALETLISGDKVFIIGNMYMHVNQYNKLKENTIKLLS
                     EYHKKYRLRKGMLKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNEKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNTLINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26124..28862
                     /locus_tag="ACOIAP_000249"
     CDS             26124..28862
                     /locus_tag="ACOIAP_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HGZ2637173.1"
                     /translation="MKSIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDTDKYETLL
                     HTIYTIFLVATGVIVFNTTKFKVDSFSTFLGLIFIATGALECIYLFNSLEIKTQFVRE
                     LNITISAITDLFPILGVYLSFKFVKDNKQIYSSIILFIVTVTLTIISLFIISGICEYL
                     GNGTSQYALEVIISIFIIIISIVSGIELNLSSSEGKWEYNEKKIFNRIIVIIILSRVP
                     NLLHIVIDDRNIERILSHIIINVAIYYLYNYIVSKNIKKTALELHDINEELTLKTESL
                     KEKNKKLIYETEKIEELKGILIKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESINYVFVYEKNVEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSREFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTDKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYNDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRSEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTELEEINIYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVISEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28981..29925)
                     /gene="manA"
                     /locus_tag="ACOIAP_000250"
     CDS             complement(28981..29925)
                     /gene="manA"
                     /locus_tag="ACOIAP_000250"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGZ2637174.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGIYKGKKLSELWDKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVDMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNLGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFRCTTFVSNEFFSVYKLDIFGKCTFTHKTPFSLYSVLDGNGK
                     LIHNAVEYNLKKGMHFILPNNFGEFGFEGNLEIICSHI"
     gene            30098..31459
                     /locus_tag="ACOIAP_000251"
     CDS             30098..31459
                     /locus_tag="ACOIAP_000251"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HGZ2637175.1"
                     /translation="MELFKEEIKKYEKEFLKLLEEWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLLSNIDDKSLYISGGIEFNTIPDKVYI
                     KNIEKLGKDNICFDINKISISYDNDNYIVHGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSARYPEIL
                     SIEEIMKKFNLYMEKNNINKFELIGENLKQANYIDKNSKLVKSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHGANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31547..33334
                     /locus_tag="ACOIAP_000252"
     CDS             31547..33334
                     /locus_tag="ACOIAP_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2637176.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIDSSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIYCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIESLMKEISDKIGFKLIEDEVIYISNYSGV
                     IACKGTQGIKNTSELEERINSVMSSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFNIKANTK
                     EEVILSLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKNLLNF"
     gene            complement(33489..34679)
                     /locus_tag="ACOIAP_000253"
     CDS             complement(33489..34679)
                     /locus_tag="ACOIAP_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2637177.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTVGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSEKGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEQKVILTPEQEERLLAFMEKDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRVLNIDHQLLKDSEMGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILKNRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(34758..34961)
                     /locus_tag="ACOIAP_000254"
     CDS             complement(34758..34961)
                     /locus_tag="ACOIAP_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGZ2637178.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENLDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(35337..35576)
                     /locus_tag="ACOIAP_000255"
     CDS             complement(35337..35576)
                     /locus_tag="ACOIAP_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637179.1"
                     /translation="MNNTRPSFYLISSAVDGNVNSIEKILAFYDPYISKCCLRPFYDR
                     YGNVCIVVDMELKGRIREALIKMMLDFDIPLETEE"
     gene            complement(35569..35997)
                     /locus_tag="ACOIAP_000256"
     CDS             complement(35569..35997)
                     /locus_tag="ACOIAP_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HGZ2637180.1"
                     /translation="MKPSNFQRTIQCQFDCKLKRVVKGIVRNYRKELKRRRNKEISYC
                     ELPEIVVEKLAVWDEYESDYTAFDVCGIEVRVLDDDLAEAIKYLSEKDREILLMYFFL
                     GMSDTEIGDRLKINRSTSFRSRKNSLEEIKKKLKENMNDE"
     gene            complement(36278..36502)
                     /locus_tag="ACOIAP_000257"
     CDS             complement(36278..36502)
                     /locus_tag="ACOIAP_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637181.1"
                     /translation="MIGLKKRDIKKALKAGAKAGGVSLSDVRADIEATIDEAMNSTDP
                     EVQANFKKYFGNKRPTSEEYIYKITQKTKV"
     gene            complement(36629..38362)
                     /locus_tag="ACOIAP_000258"
     CDS             complement(36629..38362)
                     /locus_tag="ACOIAP_000258"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637182.1"
                     /translation="MKKLKEILFLSDKGYTDLKKAIIACTITNLAMLLPFCITVMVFS
                     ELLNPFLGQELDWQNIWLLWGAGIISAIIVFLASKNDYRKTYIASYKESNVTRLRIAE
                     HLRKLPMSFFNTKDLSELTTNMMSDCSSMESMLSSTIPPLIANGISVTLTCVLLALFD
                     WRLALCVFITLPIAFLVIWCSRKYQIKLFEKQVETKLNASSQVQEYLEGIKIIKSCNL
                     SGVHFRTLNRALLEMKKIAVKVEMVVGIFMSSASMILQAGIGITIFVGTILLVNGQIE
                     LLPLLMFFLIVTKIYGPILAILSQLTTLLNLNVVTERMKTLLTTPAMSGKEETPQTYN
                     IKLNDVSFAYNNEDVIHNVSCTIPQGSITALVGPSGSGKSTIAKLIARFWDIQSGSIT
                     IGNKNIKTINPENLMEKMSFVFQDVTLFNDTVFNNIQMGNPNATKEQVYKAAKVAYCD
                     EFVRNLPNGYDTILGENGSTLSGGERQRISIARALLKDSPIILLDEATASLDPENEVF
                     VQKALAHLIKGKTVIMIAHRLRTVVDADQILVMENGKIVEHGTHNELMERKGLYHKLY
                     SIQQESLGWSV"
     gene            38412..39962
                     /locus_tag="ACOIAP_000259"
     CDS             38412..39962
                     /locus_tag="ACOIAP_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637183.1"
                     /translation="MFPHFSITSIFLKKTRVVAYCRVSTGSDEQLVSLQAQKAHYESY
                     IKANPEWEYAGLYYDEGISGTKKENRSDLLRMLSDCETGRIDLIITKSISRFARNTTD
                     CLEMVRKLIDLGVHIYFEKENINTSSMESELMLSILSGLAESESISISENTKWAIQRR
                     FQNGTFKISYPPYGYQNIDGQMIINPKQAEIVKYIFAEVLSGKGTQKVANDLNQKGIP
                     SKRGGRWTATTIRGILTNEKYTGDVILQKTYTDSHFNRHTNYGEKNMYLVENHHEAII
                     SPEDFEAVDAILNQRAKEKGIEKRNSKYLNRYSFSSKIICSECGSTFKRRIHSSGTRK
                     YIAWCCSKHISNITECSMQFIRDEDIKTAFVTMMNKLIFGQKFILRPLFHGLRNQNNA
                     ASFRRIEELETKIENNMEQSQVLTGLMAKGYLEPALFNKEKNALEAERERLLAEKDQL
                     TRSVNGNFAKVDEVDRLLKFATKSKMLTAYEDELFEDYVERIIVFSREEVGFELKCGI
                     TLKERLVN"
     gene            39963..40376
                     /locus_tag="ACOIAP_000260"
     CDS             39963..40376
                     /locus_tag="ACOIAP_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637184.1"
                     /translation="MGHTPYGYRIEDGKAVVDEKTSEQVKELFSGYLAGLSLKEAAKK
                     AGIDCYHATAGKMLQNKHYLGDEFYPPIIDEETFEKAREEKRKRAEKLGRIREPKDEP
                     KTDYPVKFKAKPLVQKYEDPYKQAEYAYSLIESEV"
     gene            40380..41951
                     /locus_tag="ACOIAP_000261"
     CDS             40380..41951
                     /locus_tag="ACOIAP_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637185.1"
                     /translation="MAVSRNVTVIPAIKRVGNNKTSESKPKIRVAAYCRVSTDSEEQA
                     SSYEIQIEHYTNYIKKNKEWELAGIFADDGITGTNTKKREEFNRMIEECMAGKIDMII
                     TKSISRFARNTLDCLKYIRQLKDKNIAVFFEKENINTMDSKGEIMLTIMASLAQQESQ
                     SLSQNVKLGIQYRYQQGEVQVNHKRFLGYTKDENKQLVIDPEGAEVVKRIYREYLEGA
                     SLLQISRGLEADGILTAAGKAKWRPETLKKILQNEKYIGDALLQKTYTVDFLSKKRVK
                     NNGIVPQYYVENSHEPIIPRELFMQVQEEMVRRANLRGRKGGKKRVYSSKYALSSIVY
                     CGHCGDIYRRVHWNNRGYKSIVWRCVSRLEEKGSECTAPTINEETLQTAVVKAINELL
                     ANKEPFLSTLQKNIATVFNEENDNATDDIEGKLEELQQQLLIQAKSKNDYEDVADEIY
                     RLRELKQNALAENAEREGKRQRIAEMTDFLNEQSCELEEYDEQLVRRLIEKVTVFDDK
                     LTVEFKSGVEIDIEI"
     gene            42306..43175
                     /locus_tag="ACOIAP_000262"
     CDS             42306..43175
                     /locus_tag="ACOIAP_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGZ2637186.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            43156..43890
                     /locus_tag="ACOIAP_000263"
     CDS             43156..43890
                     /locus_tag="ACOIAP_000263"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2637187.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            43923..44831
                     /locus_tag="ACOIAP_000264"
     CDS             43923..44831
                     /locus_tag="ACOIAP_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGZ2637188.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPAEEKGYSYIILFDDYNKIDLT
                     LLPLEELGNYLNDDKLIKIILDKDGRIQQAVVPTDMDYHIRKPSAREYDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            44828..45370
                     /gene="sat4"
                     /locus_tag="ACOIAP_000265"
     CDS             44828..45370
                     /gene="sat4"
                     /locus_tag="ACOIAP_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HGZ2637189.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            45463..46257
                     /locus_tag="ACOIAP_000266"
                     /note="aph(3')-IIIa"
     CDS             45463..46257
                     /locus_tag="ACOIAP_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HGZ2637190.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            46533..46664
                     /locus_tag="ACOIAP_000267"
                     /pseudo
     CDS             46533..46664
                     /locus_tag="ACOIAP_000267"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            46740..47485
                     /locus_tag="ACOIAP_000268"
                     /pseudo
     CDS             46740..47485
                     /locus_tag="ACOIAP_000268"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            47596..48255
                     /locus_tag="ACOIAP_000269"
     CDS             47596..48255
                     /locus_tag="ACOIAP_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGZ2637191.1"
                     /translation="MKPKIIMHTQISLDGRIKGFDNPEVYYQVAGGIHSDAVLFGSNT
                     VFTAFEKYPAETEADFEKIITSPEDPRPIGVIPDSRGILRSLHCLRNLGYLKEIVILV
                     STATPKEYLNYLEERHYPYIVSGNDHVDYEKAFQILHEQYGCKYMRTDSGGGLTNKLL
                     ENGLIDEISLVISPCFVGNKEKQLFDNLLLSEKVNLELQGTENAEHGCLSLRYAVKNK
                     D"
     gene            48917..49168
                     /locus_tag="ACOIAP_000270"
     CDS             48917..49168
                     /locus_tag="ACOIAP_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637192.1"
                     /translation="MIHVVKIPVKNKTKEVVRITVYCRVSKNIEEQRSGLNSQIAYFK
                     ELSNKVIEIDLAEVYHDVGRSGLIKNGRTSYKKMIVDGL"
     gene            49287..49658
                     /locus_tag="ACOIAP_000271"
     CDS             49287..49658
                     /locus_tag="ACOIAP_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008818840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637193.1"
                     /translation="MSCHSIGHGLNSVSKKVLELYDEGKIEFSVAKDLLYTTRNAVHY
                     CDGNTYEAIACFDGCRCARCLKKTNELYGLYDALDECREYYDIFSNKEDGVLSGDLCK
                     DCFDEICEKHHSIIIEDEVVY"
     gene            50001..50474
                     /locus_tag="ACOIAP_000272"
     CDS             50001..50474
                     /locus_tag="ACOIAP_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637194.1"
                     /translation="MNWSFSDKMFVYFINDLEMYSKWEYSGESELLMLEYKEGILSFD
                     NIMQFYLDKMMRDKVIDSIPSFFQQLLRICKKFKALKDISNAFGRDKLIQVTKENILI
                     IFHQVWQRYLYRENISVFKTMENELYTIFKGMKWNSFMNKIKVFVQKPEVKYINL"
     gene            complement(51089..52906)
                     /locus_tag="ACOIAP_000273"
     CDS             complement(51089..52906)
                     /locus_tag="ACOIAP_000273"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637195.1"
                     /translation="MAKKTPKQVKPKTGLARCMELASNKKGLIFISAILSSLASIASF
                     IPYIAVYFIIRSILQVYPNLNSLDVNEVIGYGWLALGGIIANILLYFLAIFCSHLAAF
                     GTLYELKVKFAEHITKIPLGYHLTIGSGRLRKIMDENIESVEGFIAHQFPDFVASVTA
                     PIVMVILLFAIDWRFGIASLVGIILAFIVQFMGYGSGAMKENMGKYQIALEDMNNASV
                     EYVRGMPVVKAFNQTANSFEQLKHAISQYTEWVLKFSLGWQNCMPAFTTIINNIYLVL
                     IPVGILIGTNAVNQKEFLMTFIFYLLFVPAVAGILNKIMYVSESFMQINGNVARMDEI
                     FNIPVLKDTQISKTFDNDNVTFDNVSFSYTGKENELAIKNVSFEAKQGEITAIVGLSG
                     GGKSTIANLISRFWDVTSGSIKIGNVDVREVGTNDLMKHISFVFQDIFLFKQSIFDNI
                     RMGNPNATKEQVISASKAAQCHDFISKLPNGYDTVVGTQGIHLSGGERQRIAIARAII
                     KDAPIIVLDEATAFSDPENEYLIQKAFEKLMQDKTVIMIAHRLSTIRNANKIIVMENG
                     RLIESGKHNDLIQKNGRYAEMWKHYTEAIDLKVQTKVVQ"
     gene            complement(53030..53980)
                     /locus_tag="ACOIAP_000274"
     CDS             complement(53030..53980)
                     /locus_tag="ACOIAP_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637196.1"
                     /translation="MDNRFNKSWYGDKAQLVDSDNDCVIIDYGCKGKGIITSYNLYDG
                     ITLCFLDFYTDEIMPSQKFNPDIISIVHCQAGRYECEFSNHQMFYLSEGYFSIMGTKH
                     LPISFSFPLKKCYAFSLVIDKHALSADTQKILNDFCLDMDKISERLKLNKNGYLSHAD
                     FELGHLFEEFYNAKDKESITYFRVKAIEFLYFINKLSGNEETEFRYFNKKYIQITKDV
                     CKYMTEHLEEKVSLEQLAYEKGINLSLLYKVFAQVYGDTPYSYIKKYKMNIASNELRN
                     SKRKINDIALSLGYSNASKFSIAFQSVYGILPKDYRKAEN"
     gene            complement(54102..55013)
                     /locus_tag="ACOIAP_000275"
     CDS             complement(54102..55013)
                     /locus_tag="ACOIAP_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2637197.1"
                     /translation="MFKKNKKQTETIKEPKEKKVRTVKVGTHKKTVIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELCLQDTNGIENFVKNFAKSYYTWNNSKEAIEARTQA
                     ISGYLTKELQDLNVDTIRTDIPTSSTATNVIVWSIEQSGTNTFSATYEVDQQIKEGEK
                     TSNVKATYTVKVHIDADGDMVIVQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATA
                     FLETFFKLYPTATEKELAYYVSGNVLEPIGRDYLYSELINPIFTKDGENVKVKVAVKF
                     LDNQTKATQVSQYELVLHKDSNWKIIG"
     gene            complement(55030..56037)
                     /locus_tag="ACOIAP_000276"
     CDS             complement(55030..56037)
                     /locus_tag="ACOIAP_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HGZ2637198.1"
                     /translation="MKLKHIALIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITV
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCQNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKYTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLMQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLSNSYWQQHLIGAGRVK
                     Q"
     gene            complement(56034..58244)
                     /locus_tag="ACOIAP_000277"
     CDS             complement(56034..58244)
                     /locus_tag="ACOIAP_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGZ2637199.1"
                     /translation="MKERIKGAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTANGFSSSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGADRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLFIFNIGITIFVFLLM
                     GIMMLSQILFIIFAMFLPISFLLSMIPSQENLAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISKDYPFFMVAFLQIVCFAGIFIKLGDLMNMFSLNAGDSQNMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQRRQNIADKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTIPKPSVEKMQEVKRPATATTSKISEPVKTSVIKERPLSSGASDRKASQPIQP
                     AHRQNVEKVVSQETHQNYKAERTTKAQTFEQSKRTTEHTEKNRNLVMKKGQKKK"
     gene            complement(58244..60694)
                     /locus_tag="ACOIAP_000278"
     CDS             complement(58244..60694)
                     /locus_tag="ACOIAP_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2637200.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLETNDFGYLIEHLYGRDGVAYEDYEYQLPKKKLRRE
                     TQIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSDSRGLLHVIDELRREDTPVSRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVAKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(60672..61070)
                     /locus_tag="ACOIAP_000279"
     CDS             complement(60672..61070)
                     /locus_tag="ACOIAP_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2637201.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(61180..61683)
                     /locus_tag="ACOIAP_000280"
     CDS             complement(61180..61683)
                     /locus_tag="ACOIAP_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGZ2637202.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNSMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GMCEIPY"
     gene            complement(61701..62204)
                     /locus_tag="ACOIAP_000281"
     CDS             complement(61701..62204)
                     /locus_tag="ACOIAP_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGZ2637203.1"
                     /translation="MQETRVLVETRGTTGEETISYWFDLPIDVAEFEEKLGVGAESGD
                     YRIIEKVLAFANEVHEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVFENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(62123..62419)
                     /locus_tag="ACOIAP_000282"
     CDS             complement(62123..62419)
                     /locus_tag="ACOIAP_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2637204.1"
                     /translation="MSDIFKDMQVKVGCEYISDQPSYKRKVWQEMKRLNLADYEERQL
                     EDFSKYVFGMPYQTLKDVMKQQKGREEQCRKQGCWWKREEQLAKKQYHTGSTCR"
     gene            complement(62520..62993)
                     /locus_tag="ACOIAP_000283"
     CDS             complement(62520..62993)
                     /locus_tag="ACOIAP_000283"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2637205.1"
                     /translation="MDYIIREIKKEEYDLLNDFLYNAIYIPDGVEPPPKSIINCPELQ
                     EYVFEFGKRKDDRALVAEVQGNVVGAIWVRIMNDYGHIDNDTPSLAMSVFQKYRGQGI
                     GTSLLQQLLLVEKTSGYSKLSLSVQKNNYAVKMYKKAGFLVVDENSEEYIMTVNL"
     gene            complement(63070..63291)
                     /locus_tag="ACOIAP_000284"
     CDS             complement(63070..63291)
                     /locus_tag="ACOIAP_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637206.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(63292..63426)
                     /locus_tag="ACOIAP_000285"
     CDS             complement(63292..63426)
                     /locus_tag="ACOIAP_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HGZ2637207.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILNIGKEADYEMKQLEESEDN
                     "
     gene            complement(63438..64634)
                     /gene="mobT"
                     /locus_tag="ACOIAP_000286"
     CDS             complement(63438..64634)
                     /gene="mobT"
                     /locus_tag="ACOIAP_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HGZ2637208.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLALASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGRYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEQQAKLTEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(64879..65295)
                     /locus_tag="ACOIAP_000287"
     CDS             complement(64879..65295)
                     /locus_tag="ACOIAP_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637209.1"
                     /translation="MEIKEINKIIQSEDKDEKSKSVKCICINYGDFLADCEGFVQKRY
                     HDFKCNPKHQFEKKADTILENAIHEKNFMPDLFLIRLNRKQSACNSQIDFVFELLDKS
                     FLETDPIRKSEISEETLNLCLSADVSFIMVYIGMNR"
     gene            complement(65299..66681)
                     /locus_tag="ACOIAP_000288"
     CDS             complement(65299..66681)
                     /locus_tag="ACOIAP_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGZ2637210.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     CTDWEHFSLLENDLTLSPYNFITILIATGACVLVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGSLKLMNNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGRLAQERQ
                     VMPEQQGKEN"
     gene            complement(66782..67108)
                     /locus_tag="ACOIAP_000289"
     CDS             complement(66782..67108)
                     /locus_tag="ACOIAP_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637211.1"
                     /translation="MDLNIVLAVICGAVALVGAFCVVFQIYHMTVIDATARGLKHPKF
                     WGVFTMSGNNSSGLLMYLIGRRKYPIVNMSESNSKELEKRKKSAGVGLLFLAIGVIGI
                     ICATLI"
     gene            complement(67124..67531)
                     /locus_tag="ACOIAP_000290"
     CDS             complement(67124..67531)
                     /locus_tag="ACOIAP_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637212.1"
                     /translation="MEIGKKLKNARVQSGMTQENVAEKINVSRQTISNWENEKSYPDI
                     ISVIELSNLYSISLDVLLKGDEKMIEHLEESTNVVKSNQKMIWAIIVNIIVVALLITL
                     NMFIPDNRYFLVGIFCLMVITSSALLYQIIKKF"
     gene            complement(67698..68081)
                     /locus_tag="ACOIAP_000291"
     CDS             complement(67698..68081)
                     /locus_tag="ACOIAP_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGZ2637213.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGSPQNHTPQGQSKK"
     gene            complement(68097..68423)
                     /locus_tag="ACOIAP_000292"
     CDS             complement(68097..68423)
                     /locus_tag="ACOIAP_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGZ2637214.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKKFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            complement(68658..71702)
                     /locus_tag="ACOIAP_000293"
     CDS             complement(68658..71702)
                     /locus_tag="ACOIAP_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HGZ2637215.1"
                     /translation="MKKMLKRLCTGFLALATVVTALPTTPVHAESKQYWTESKERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFRNGYKTRADASTRMSADQISDVA
                     LSIEYVKQYTDSHSGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFSGARAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKASSNTSITDGNG
                     NYSIAGATYGVFADKDCTKQLATLTTDENGNTDVAEVKAGTVYIKELSAPAGYKVDKT
                     VYSLKVEAGTTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDGDGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQAGDKSEQIKGLYVTQITEDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNENAVLVEGKLYKKNEVVKTIR
                     TDIEGITSTSADLLPYGKFRIVESEAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGENHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVVDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENTELIIDGKRVENDYTFVADDEEMKVEISYTFNASALGGKNLVTFEELYD
                     FSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTFIDTVT
                     LEGLEVGTQYKLVGWQMLREENAELLINGKRVESDYTFIADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPETPPTPEKPN
                     RPSDSPKTGDNTNLYGLLALLLTSGAGLAGIFFYKRRKMKKS"
     gene            72130..72585
                     /locus_tag="ACOIAP_000294"
     CDS             72130..72585
                     /locus_tag="ACOIAP_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2637216.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKELNLAEDESLVY
                     EGLMSREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKDFKDSLLKSDNVEEISNLINEALGL"
     gene            72643..72960
                     /locus_tag="ACOIAP_000295"
     CDS             72643..72960
                     /locus_tag="ACOIAP_000295"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: protein motif:HMM:NF014368.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGZ2637217.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            72985..74247
                     /locus_tag="ACOIAP_000296"
     CDS             72985..74247
                     /locus_tag="ACOIAP_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGZ2637218.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKKLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAVWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            74352..75416
                     /locus_tag="ACOIAP_000297"
     CDS             74352..75416
                     /locus_tag="ACOIAP_000297"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HGZ2637219.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     EAQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIIDFIKVGMTE
                     KQVENEIVRVIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITKDGCMRLTTSTKDLIVVS"
     gene            75470..76648
                     /locus_tag="ACOIAP_000298"
     CDS             75470..76648
                     /locus_tag="ACOIAP_000298"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGZ2637220.1"
                     /translation="MYNFDNKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVDVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEAQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTKVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIEKELLENVILLTSPNKGFNLGGLKTSYSIVINKNIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLNGVNEYIKSNYELLETWVNKYSKIKLMKMESSYLAWMDISGL
                     GISASEFTDRLAIDTGVLLEDGSHFVQDGDKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            76844..77041
                     /locus_tag="ACOIAP_000299"
     CDS             76844..77041
                     /locus_tag="ACOIAP_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2637221.1"
                     /translation="MKNCVEALRKKKGLNQEDFAKILKVSRQTISSIENGKYNPSLEL
                     AFQISDFFEMSIEEIFLWKEI"
     gene            77045..77479
                     /locus_tag="ACOIAP_000300"
     CDS             77045..77479
                     /locus_tag="ACOIAP_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurium resistance protein TerC"
                     /protein_id="HGZ2637222.1"
                     /translation="MEKRNLRIGIVYVVLGVTFLFSCLMTKDKLSSLLVGLAAGFGFN
                     GISIIYRYFYWNKHKEEYREKLEEEKINLQDERNVMYRDKAGRYAYIVCMIIIPISAF
                     VFAVLNALDIYNSLVIIIYLSVLWIVLYVVGVIYYRKLKNNE"
     gene            complement(77655..78710)
                     /locus_tag="ACOIAP_000301"
     CDS             complement(77655..78710)
                     /locus_tag="ACOIAP_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGZ2637223.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSGQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVKVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLNKENMKIDLGAIAKGYAADKIVSYLKSEDIKKGLVNLGGNIFTLEDSKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINRIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKAFSIEKLNK"
     gene            78777..79148
                     /locus_tag="ACOIAP_000302"
     CDS             78777..79148
                     /locus_tag="ACOIAP_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HGZ2637224.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            79185..79859
                     /locus_tag="ACOIAP_000303"
     CDS             79185..79859
                     /locus_tag="ACOIAP_000303"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGZ2637225.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            80107..80946
                     /locus_tag="ACOIAP_000304"
     CDS             80107..80946
                     /locus_tag="ACOIAP_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGZ2637226.1"
                     /translation="MNFKKLSNVKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDKNAKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            81188..81284
                     /locus_tag="ACOIAP_000305"
     tRNA            81188..81284
                     /locus_tag="ACOIAP_000305"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:81222..81224,aa:Sec,seq:tca)
     gene            81435..82142
                     /locus_tag="ACOIAP_000306"
     CDS             81435..82142
                     /locus_tag="ACOIAP_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HGZ2637227.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NQDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIINELLGQ"
     gene            complement(82284..83120)
                     /locus_tag="ACOIAP_000307"
     CDS             complement(82284..83120)
                     /locus_tag="ACOIAP_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2637228.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEYSKNIINSYLRQKRIKTIDIIIATHPDSDHIGSLDNVIKKFNVNSIY
                     MPEQSTNSESYQNLINSCTDKNLAIQYLYKDDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNNNSFLFMGDAEEENEKEILRSFELNNINFIKIGHHGSNSSSSLEFIKKIN
                     PDIAAISCGYKNQYGHPHKEVIDNLKQSHVSIYRTDRIGDIVFYSDGEIIFTKYNYEV
                     DT"
     gene            83307..84212
                     /locus_tag="ACOIAP_000308"
     CDS             83307..84212
                     /locus_tag="ACOIAP_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol lysyltransferase
                     domain-containing protein"
                     /protein_id="HGZ2637229.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPDRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYESKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            84221..85405
                     /locus_tag="ACOIAP_000309"
     CDS             84221..85405
                     /locus_tag="ACOIAP_000309"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2637230.1"
                     /translation="MEIRYAKEEDIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNNKVYNTSYVVGVSTLPEGRGTGYMSKVIKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     RIDRAFLNEVNGNVLKDEHYYKNLFKEIQSEDGFLYIHEGNEKDGYIVYFINEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPIIDKIRFILDNPKDSEIKIKPFMMG
                     RIINVKKFIEDVDIENDINSSFNLLIEDKFINENNGLFKISIQNKKVSVEQLYKKDEE
                     KPQEDFDVKLDINTLTQLAFSYIDVNEAIFLNDIKDVSEETLEILNCIFSKKNNYINE
                     YI"
     gene            85520..86821
                     /locus_tag="ACOIAP_000310"
     CDS             85520..86821
                     /locus_tag="ACOIAP_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HGZ2637231.1"
                     /translation="MGVIIIQIRRPLLIILVFVIAISFIITNNTKNNEEINDKIITIQ
                     GIVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKFYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLSEEQKEIFTRTGTSHVISISGLHTGILCIIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIIYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIEKPKF
                     YIVIIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKF"
     gene            86775..87818
                     /gene="holA"
                     /locus_tag="ACOIAP_000311"
     CDS             86775..87818
                     /gene="holA"
                     /locus_tag="ACOIAP_000311"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGZ2637232.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGSNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(88008..88274)
                     /gene="rpsT"
                     /locus_tag="ACOIAP_000312"
     CDS             complement(88008..88274)
                     /gene="rpsT"
                     /locus_tag="ACOIAP_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGZ2637233.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            88596..89225
                     /locus_tag="ACOIAP_000313"
     CDS             88596..89225
                     /locus_tag="ACOIAP_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2637234.1"
                     /translation="MNLIKNYKNTEDTADKLISYIDENCSGHLFALCGVSLGGQIVME
                     LLSRKPNITKKAIIDGSICYPRPLMARFCITGIRFFGGLLFSKKACRFQIAMMPKLLP
                     ENMQYPDEIKAYYMTDMPHVRKETFYNMYRTYMMNYILKENVKKTTAQVMYWYGEKEM
                     KCVKKSAKMFQSYVPSCEIYEAKGYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            89567..90520
                     /gene="gpr"
                     /locus_tag="ACOIAP_000314"
     CDS             89567..90520
                     /gene="gpr"
                     /locus_tag="ACOIAP_000314"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HGZ2637235.1"
                     /translation="MINVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDEQGSEIMNKDIGKYITLESNLMKFDDDESREEMISYLKDELVDIFGQDENKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            90538..91557
                     /gene="spoIIP"
                     /locus_tag="ACOIAP_000315"
     CDS             90538..91557
                     /gene="spoIIP"
                     /locus_tag="ACOIAP_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061783 - peptidoglycan muralytic activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HGZ2637236.1"
                     /translation="MFKKCIKVVTLTFILACILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTEDKKNNKNKETSKENKEESKEEKTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNATSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            91588..91839
                     /locus_tag="ACOIAP_000316"
     CDS             91588..91839
                     /locus_tag="ACOIAP_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637237.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRIMFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPNIKFDITKFDFDIPNFDIHEIIRKFNK"
     gene            92121..93926
                     /gene="lepA"
                     /locus_tag="ACOIAP_000317"
     CDS             92121..93926
                     /gene="lepA"
                     /locus_tag="ACOIAP_000317"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGZ2637238.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            94075..95412
                     /locus_tag="ACOIAP_000318"
     CDS             94075..95412
                     /locus_tag="ACOIAP_000318"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGZ2637239.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMVEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSETGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFNIDEGTEQSIHKKSDLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGHILNNMLEIVINNPELNEKEILKEKALNIYTF"
     gene            95645..96958
                     /locus_tag="ACOIAP_000319"
     CDS             95645..96958
                     /locus_tag="ACOIAP_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGZ2637240.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIIFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITMGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKALLKVNSGGSPVNSI
                     LLITALACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLYRPYRVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            97130..98305
                     /gene="hemW"
                     /locus_tag="ACOIAP_000320"
     CDS             97130..98305
                     /gene="hemW"
                     /locus_tag="ACOIAP_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGZ2637241.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDLKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFMSIKEMFYIDDN
                     AEITIECNPGTLTLEKLKTMKDIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENIDIEMYEYTINYLMSKGYNQYEISNYSKEGFNCKHNILYWECKPYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFKDKYSKQIEMLSARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            98408..99427
                     /gene="hrcA"
                     /locus_tag="ACOIAP_000321"
     CDS             98408..99427
                     /gene="hrcA"
                     /locus_tag="ACOIAP_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGZ2637242.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLVNQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            99457..100077
                     /gene="grpE"
                     /locus_tag="ACOIAP_000322"
     CDS             99457..100077
                     /gene="grpE"
                     /locus_tag="ACOIAP_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGZ2637243.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSNEKT
                     DEKEVDDENVTDINSKLAEKKLQNELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGIEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            100169..102016
                     /gene="dnaK"
                     /locus_tag="ACOIAP_000323"
     CDS             100169..102016
                     /gene="dnaK"
                     /locus_tag="ACOIAP_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGZ2637244.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSSEKEEIEKAIADLKTVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            102227..103381
                     /gene="dnaJ"
                     /locus_tag="ACOIAP_000324"
     CDS             102227..103381
                     /gene="dnaJ"
                     /locus_tag="ACOIAP_000324"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGZ2637245.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRTRRRGPQRGADIRQSVTIYFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSTCNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            104356..105291
                     /locus_tag="ACOIAP_000325"
     CDS             104356..105291
                     /locus_tag="ACOIAP_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGZ2637246.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            105324..106697
                     /locus_tag="ACOIAP_000326"
     CDS             105324..106697
                     /locus_tag="ACOIAP_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2637247.1"
                     /translation="MSKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMYLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGRWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(106885..>107384)
                     /locus_tag="ACOIAP_000327"
     CDS             complement(106885..>107384)
                     /locus_tag="ACOIAP_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HGZ2637248.1"
                     /translation="IVNSKYNLDINVTTQNIIETETYQSTYIFYLGKLDSKADFDFRL
                     QLCSDLLPHIIKDNAENKFLNLFDLIRYKTLDLINEDNILNKLIDFNKIKSIDEELLY
                     TGLKFINNDLNISKTSTSMFLHRNTLVYRLEKINEILGFDLKNFENAMIFYLSVKSYF
                     LYKKI"
BASE COUNT        38581 a        15067 c        19255 g        34481 t
ORIGIN      
        1 tatattaaag ttatttagta agaggtgtat tttattaatt tattaatctt aataatttta
       61 aataaagtca aaaaaatgta ttttgagtaa ataaagtaaa taaaataata taaaatataa
      121 atttcaataa aaataataaa gtatatattg ttgccttgat gagaatgtaa aaaatatttt
      181 taaattatca tttaatgtaa cttaaatgaa ttgaagatat atgtttattg tattcaattg
      241 ttgtattttt aggttttttg tgattaatta aaaaattata aaaatcgttt acatgttgat
      301 ttttaaaaaa aaaagatata gaattatata gaaagtaata aacaaaaatt ggatttacgg
      361 gagtggaatg aaatgatgaa tgttacctta acagatgtga aagaagctag agagaccatt
      421 aagaacatag taaaaagaac tgacttactt gaaagtgtta aacttagcga aaaaacagga
      481 gcaaatgtgt tctataaatg tgagaatctt caaaaaacag gttctttcaa attaagagga
      541 gcttgtaaca aaatagcaag tttgacagat gaagaaaagg caaatggagt tatagcttcg
      601 agtgcaggga atcatgctca aggagttgca ttgggggcaa aaatgactgg tataaaatct
      661 acaatagtaa tgccagcaac tgcaccttta gcaaaagtta gtgcaactaa aagttatggg
      721 gcagaagtag ttttaaatgg tgcggtttat gatgatgcat atgcaaaagc tgttgaaata
      781 caaaaagaaa caggagcaac tttcttacat ccattcaatg atagatatgt tatagcagga
      841 caaggaacta tatctcttga aattttcgaa caattagaca ataaagttga tactatacta
      901 tgcccagttg gtggaggagg aatcatctct ggtgttgctg ttgcagcaaa agcattaaat
      961 cctaatgtaa aagtagttgg tgttcaaact gcaaatatac cttcaatgaa agagtcaata
     1021 aaaaatggaa aagtaacaac agcatttaat gatactacaa tagctgatgg tatagctgtt
     1081 aagactccag gagatttaac ttttgagata ataaatgaat tggttgatga aatagtagtg
     1141 gttgaagaga cagaaattgc agaatcaata ttatttatga tggaaagtca aaaaatagtt
     1201 tcagaaggtg ctggggctgt atgtacagct gctatattaa gtggtaagta tgtgccagca
     1261 aaagatgaaa atgtggtttg tataatatct ggtggtaata tagacataaa tactttatat
     1321 agaataatag gtgttgcttt agctaaagaa ggaagaagat attcatttag tacaattatg
     1381 gaagataagc caggaaactt tgctgagtta actagaataa taagtgagaa tggtggaaac
     1441 attttaagtg ctaatcaagg taaattatca gcaggggaag ctctaggaaa acaaagtgcg
     1501 gaatttatat tagagacaat agattatgac catatagcta gaataaagaa agctatagaa
     1561 gaaaaaggtt ttaaaattat agaattataa taaaaggtgt atataatata caagaaaaat
     1621 agtataatag tgtatgaaga tacattttat atgtattaga ttaacgaatt aggaggattt
     1681 taaaatgaaa catgaagtaa tacatactaa tgatgcacca gcagctttag gaccatactc
     1741 tcaagctata aaagctggaa acttattatt tgtatctgga caagttcctc ttgtaccaga
     1801 gactatggaa gtagttgaag gagatgtaca agctcaaact gctcaatctt taaaaaatct
     1861 taaagctata ttagctgaaa gtggagctga tttttcaaat gtagttaaaa ctacagtatt
     1921 tataaaagat atgaatgaat ttggagctat aaacgaagtt tatgctgaat attttggaga
     1981 aaataaacca gcaagagctt gtgtagaagt tgctagatta ccaaaagacg ttaaagttga
     2041 aatagaagta atagctgtat tataaaaata caatattttt aatttgaaaa ggctgaagaa
     2101 ctatattcta gtgattcagc ctttttataa aaaataaatc aaaagcttaa agagcttgat
     2161 aaatattgtc gaattaaaaa ataaaattaa aataaatatt gcaatatttt tgagaaggtt
     2221 ttataatgag tatataattt gaaacgtgta actattaaat taggcatgag ttcttggata
     2281 tttttatcct gaggattcat gccttttttg tattgaaaat caaaaatcta tttaataagg
     2341 aggaagtact gtgttaaatt ttttcaagaa aaataaaagc tataagttac atgcagtagt
     2401 gagtggtaac tgtattaata ttgaaaaagt aaacgattct gtgttttcaa aaaggttaat
     2461 gggagatgga gttgcaatta ttcctaatag taatgttgtt gtagctcctt gtaatggtaa
     2521 agtaactgtg cttacagagt caaagcatgc atttggtatg gtctcagatg agggtgttga
     2581 aatattagtc cacataggaa ttgatacagt taatttacaa ggtgatgggt ttaaaaatga
     2641 agtgtctcaa ggagataatg ttaaaaaagg tagtccaata ataagctttg aaagagaaaa
     2701 aataaattct cagggaattg attgtacaat aataatggtt gtattaaatc atagcgaatt
     2761 ttcagaaata aattgcatgg tagaaaatga agttgttgca gggcaagata ctgttattga
     2821 aattatgaaa tgataggaag ggattaattc aatatgagag tagtaaaaat ctttaataat
     2881 aatgcattat ctacagtaac taatgatagg aaagaagcta ttttactagg tcttggtata
     2941 ggttttaata aacgtccagg agataaagct aatgaagata aaatagaaaa gatttattat
     3001 gttcaagacc acatgcaaac aaaattttta gaattgttaa aaaatgttag tccagaagtg
     3061 atggatgctt cacaacaaat tataagtctt ataccaggga atgagggaaa atttaataat
     3121 aaagggatat tatctttagt ggaacatatt agttttgcaa tagatagaat gaaaaataat
     3181 gtttttctac ctaatttaat gcttttggat ataaagatga tgtattcaaa agagtttgag
     3241 ttaggagtaa aagctttaga agttatatac agagtatgtc atatccattt gcctgaagat
     3301 gaagcaggtt acatagcttt acattttgtc aatttacaat caaatgataa tttggcatat
     3361 gatactttaa aatttgtaaa aggtagtatt aatttgatta aagaatgtta tggattagaa
     3421 ttagacgaat cgagtttgag tacattacgt tttaggactc atcttaaatt tcttgctcaa
     3481 agaattttta agaatgaaat ttgtcaggat gataaaatga ttgaaatgta tgattattta
     3541 attaacaatc atcctaaaaa taaagaatat ttagaaaagt taaatatata tattgaaaag
     3601 gagtttaggt ataaattaga taaacctgaa aaaatttatc tactgctaca cttaacaaaa
     3661 atcttataag aatgagatga attagtaata gaaatatata taattttaag gggggataag
     3721 attgaaagat aaactacttg gaggactgga aacatttgca aaggcaatgg ttcagccatt
     3781 aatgtattta tcaagtgcag ggatattaat ggtggtaggt gtactactta caaatgatat
     3841 gttactagga gtatttccat tttttaaatg ggagccaatt caaatatttg gaagcctaat
     3901 ttataactgt ataatggcta ttattaataa tcttgctgtt atatttgcta taggtattcc
     3961 tgctgcacta gcaaaaaaag agaaacacaa agcagcatta ataggattta tgagttatat
     4021 aatatacctt acagcttcta acactatgtt aacatcacta ggtcaaatag caaaagaaag
     4081 caagatgctt gggttgatag ggactggaca agctactatt ttaggtattc aagttgtaga
     4141 tacaagtgta tttggtggaa ttattttagg gtgtatagct ggatatgtat ttaatcgtac
     4201 aagtaacaaa acatttaaag gagctttaca gatatactca ggagcaaatt ttagttttat
     4261 atgtatgttc tttgtatcca ttttaattgg cgttgtgagt aactttatat ggccattagc
     4321 tcaacaagga atagcttctc ttgcaaatgt catcaaagat acaggtacat ttggtttatt
     4381 cttatatggt tttttagaga gaatattagt accaactgga cttcatcatt taatctacac
     4441 accatttcag ttttctgatt taggaggagt gcttaaagtt ggtgtagata cagtttcagg
     4501 agcttatgct atagttatga cagaaatgaa tttaccagtt gagcgtttct cagatagtat
     4561 atactacatg gcaactggat ttacaaagat gtttggttat ataggtatag gagctgcctt
     4621 tatttatact gcatataagc aaaataagaa gaaggttaag gcaacgatta ttccactaat
     4681 aattacggca gtattagcct ctgtaacaga accattagac tttatgtttg tattctgtgc
     4741 accactttta ttctttgtac atgcagttat agctggtcta tttatagctt tattaaaaat
     4801 atttgatgtt actgccttat gtggagggaa cttattagta tcaattataa tgaatactac
     4861 agtaggtgta gaaaaaacac actggccagt aatgatgata ttaggacttg cacaaattat
     4921 tgtatatttt gtagtattta gttttttaat taagaaattt aattataaaa ctccaggtcg
     4981 tgaagatgag agtacagcta caggcgaagg acaatcaaaa caacttaatt tagatacagg
     5041 tatagaaaat ataattgatg ggttaggtgg aaaggaaaat attaatacag tagaaaattg
     5101 catcactaga ttacgtgtta atgtaaaaga tgaaagtaag attaatgaag atataattaa
     5161 tttaacgcca aatagcggga ttgtaaggaa aggaaaagat atacaaataa tttttggact
     5221 tcatgtgcat gaggtaagac gtgcagtaga agatttttta gaaatttatt aaagatacat
     5281 ataatttata tagagtttat agaggaggaa taattattat ggttattact attgttggag
     5341 gaggaagcac atttactcca ggtattgtta agtcaattgc attaagagaa aaagagttag
     5401 agcttgaaga aattcgttta tttgatattg ataaagaacg tcaagataaa gtagctgtag
     5461 ttgtcaactg gatactaaaa gaagatgtta aaacagatgt taaactaact gtaactaatt
     5521 gtgaaaaaga agcttataca gatgctacat ttatatttgc acaaatgcgt gttggtaaat
     5581 atgaaatgcg tgagcaagat gaaaaaattc cattgaaata tggttgtgta ggtcaagaaa
     5641 cttgtggttg tggagggatg gcatacggat tgcgtacaat acaaccaatg ataaaggtta
     5701 ttgatgatgt agagaaatat gctaaaaaag gttattggat attaaattac tctaatcctg
     5761 ctgcaatcgt ttctgaagct tgtcgtaagt taagaccaaa tgcaaggatt ataaatatct
     5821 gtgatatgcc aatagctatt atagatatga tagcggggtc attaaatatc aatgacgtcc
     5881 ataatatacg ctatgattat tttggtctaa atcattttgg ctggtttact tcaatagatt
     5941 ataaacatag agacttaatg gaagagatta aggaatacat aaaagaaaat aaaatattac
     6001 taccaaaatc ttatatagaa aacttaaata aaagtcgtag tacaggaaat cgtcatgctg
     6061 taagtagctg gatacatgtt tgggaatctg tttatacaat gttagaaaac ttcccaaaat
     6121 atctaccaaa cacttattta acatactatc ttttaagtaa agaaacagtg gaacattcaa
     6181 acataaatcg tactcgtgca aatgaggtta tggaaagccg tgaaaaagac ttatttgaag
     6241 gtgtgagaca ttacttagaa actggagaaa tttctgaaaa agcattttat gcaggctcac
     6301 atggagattg gattagtgat ttggcagttt caattaaaaa tgatacacgt agtcgttttt
     6361 tagttataac tgaaaatcgt ggagctatcc caaacatgcc atatgatgca atggtagaaa
     6421 ttccagcata tattggtaaa gatggtccag aagttattgc tcgaggtcca atacctctat
     6481 tccaacaagg attaatgatg caacaactta acagtgaaaa attgatagta gaagcttata
     6541 tagaaaatag ttatgaaaaa gctttacaag cattcacatt aaataaaact attccaagta
     6601 tgaatgttgc taaagaaatt ttggatgaaa tgatagaagt taataaggaa tactggccag
     6661 agctaagata gtaggataga agaaaaggtt tttatttaat aattaggtat gttttcagag
     6721 tcttttatca aaatgtattc acaaacatat ggcaatatat taaagtaaag agtgatattt
     6781 ttagaagaat ggggtgatgc aatgaacatt ataaataaaa ttttttggca agaagatagg
     6841 attggcatga ttacaaataa tttagaggca gatacacata gtcactgcat gttacaaatg
     6901 ttcttaggga tagaagaaaa cattgaaata atagtcaatg aaaaattagt taaatgtaat
     6961 tgtatcgtag tagataaaaa tatctctcac tcattttcag caagaaaaaa agtttattac
     7021 tctgctatta ttgaacctac atctatatat gcagaacagc ttacctcaaa aatgagtgat
     7081 tttggctact ggatatgtga caatgatgga ttagagaaat tacgtcaaca aggaactttt
     7141 ttgatatata attctagtaa agaacaatat ttaagattta tggaaatgct taataactat
     7201 ttgaatatac ctataactct caaaaattat gatgacagaa ttactgaatt gctcaattta
     7261 ttacgtactt gcaattgtga taatcatact atttcaagtt ttgcagataa agtgtcccta
     7321 tcagcaagta ggctatcaca tctgtttaaa taacaaatag ggataccttt aaaaagctat
     7381 atcttatttc atcaaatgga gtgtgctttt agagaattac tttctggaaa aaatgttacc
     7441 gaaacttcta tgactgctgg attcgatact ccatcacact ttgcagggac agttaagcga
     7501 atgatgggaa tgcccgtttc tttatctttg aaagatagcg agtttttgaa agtatattga
     7561 atattctcgt tatataatga agttgtatta agaaaggggc tttattatga ataaagaata
     7621 tttagaagaa acaaaaatgt taaattataa tgaaccacaa cttaagctct tggtatcatc
     7681 aaagaagtgg ttggaattag atgattttta taaaataaaa tctatttatg agtttgtaca
     7741 gaatgatatt ttatttggat ataatgcttc tgatatatta agcgcaacac aggtattaaa
     7801 tgatggtatg ggacaatgca atacaaaagc tactctttta atggcattat tacgtgcagt
     7861 gaatatcctt tgtaggcttc atgcttttga tgtaacaaaa gattttcaac gaggtgctac
     7921 atccaaattg atttcactat tagcaccaaa atatattctt catacttggg tagaggtatt
     7981 ttatcaagat aggtggattg ctctggaggg tgtcataact gataaaaaat atttagaagc
     8041 aattcagaag aaattttcta attatggtgg aacgtttaaa aagtatgcaa tagctacaaa
     8101 tgatttgaaa aatacatcta ttgattggga tggtaaagat acttttatcc aaaaagaagc
     8161 tatcgtgtat gattatggta tttttccatc accagatgta tttttttcta ctcattcaca
     8221 acatatgtca aaattaaaga atttcatata tgtacatctt atcagaaaaa taatgacaaa
     8281 aaatgtatgt aaggctagaa ataattatat tgataaaaac gaatgagtgt ttaagaagtg
     8341 actatatagg aaatatatag aacaattaaa actgtattgg ttaaaatgaa taaaaaggag
     8401 ttatcaaaga gcaaacttaa attgttcata ggataactcc ttttttatat taacttctaa
     8461 taatttggtg tctttttata aaacatatag atacaattaa accaacaaat gcaagagtag
     8521 ctgctattga aaatgcaaca tctattccat ggatattaga cagtatagca gaactcatgt
     8581 gagctttttt agtagcactt gtcattatag taataagcac agcagaacct atagcaccag
     8641 atatctgacg aagtgtacta ttaatcgctg tggcatgaga tatgagttct ctgtctagtg
     8701 ttttaattcc ccatgtagtt aatggcatca aaaccattga gataccaatc atacgaatac
     8761 aatacatcaa tgatacatga agtaaagatg tatccctacc taaaaaagca aaagatagag
     8821 ttcctaaaaa taaacatcca gttcctaata tcgatagagc atgaggacca tatttatcta
     8881 aatgacgtcc tgcaactgga tttaatacaa ccattaatat agcgccaggt aacattaatg
     8941 aacccgaaga caatgcagaa aatcctctta cagactgaac atatagagga atcattaatg
     9001 tagcagacat cattgaagca tatacaatca taattaatat tgtagaaatg agaaatggtt
     9061 tatttttaaa aaccctcaat tctaaaaatg gttctctaga ttttaattga cgtagtgtaa
     9121 agaaaattaa tgatataatt cctatgaata ttggtaaata tgtggcaata ttagtccacc
     9181 cataattacc ttgattagta aatccaatta acaaaccacc aaaacctaga gatgacagta
     9241 ttattgaagg aatatctaat tttagttttt gcgtttctcc aacatttttt agtagaataa
     9301 atgaaagtat aacatctagt atagctatag gagaaagaag caaaaataaa ctatgccagc
     9361 caaatgaatc tactaaccat cctgataaag ttggtcctat tgctggagca aatcctactg
     9421 taataccaac taaactcata gctgcaccac gtttttcctc agggcataaa tatagtataa
     9481 taacttgtaa aagtggcatt agagaaccag aacccattgc ctgcaacaca cgagcaacca
     9541 acatagttga aaaattatta gaaaaaagtg caataataca tcctatagaa aatatagaca
     9601 ttgatgtaat gaataacttt ctagtactaa atctatttat caaataggct gttgtgggca
     9661 caataatacc tgcaataagt agatatattg tcgttaacca ctgaccaaca tcagcagtaa
     9721 ttttaaaatc tgacattata ttaggtaatg ctgtagataa tagtgtttga ctaagagaac
     9781 ttataaaagc accagtcatt acgattgcta ttattaaatt tcctttttta ttgttacttt
     9841 gggtttccat aatttacaac gtctcctttt ttaattgatt tttaatgctg ttcaataaaa
     9901 gtacctttgg tctcaaagtg tcttcttttt ccaaatatgc aatcattgaa tccataatta
     9961 aagaatcata ttgttgattt tttccctcga catataattt ttttgttgct tctagtaatt
    10021 tagaattttc aaggagagaa gtatctgttt tgattagttc ttctatatct tgtatcgttt
    10081 taaaaaatag cgatttatta taaagggaaa agtaagcttc atcttcttgt ttatgtaaaa
    10141 acattgattt ttcaattaaa ggatttagat tatccatatt ttctacaact aaatctagaa
    10201 tttgtatagt aaatttagca acaaagtata catttatttc tcttttctgt acatgaataa
    10261 tgtatataaa ctgatgaatt agagcatcca ataagaaaac taaatcaaat atgatgtttt
    10321 ctattttatc accatagtta tcaaataagc ttagcttgta ttcattcaat aagttagctc
    10381 ttgattttgt ttgcaattta cttgtagtct tacgttgcac ttcagaaaaa ttttctctta
    10441 tgtaggtatt tatggtagtt ctagaaaaaa tattttccca tacagcaatt atctttctgt
    10501 ttaacttttc agatgatgga atatcattat tttcattgat agaatgtata atttctaaaa
    10561 acttttcatc ataataattg attatttcgc agataaaact ttccttagtt tcaaaatgct
    10621 tgtaaaaagt agctttagac attttgcact cttttacaat gtccgagatt gaagtatttt
    10681 gaaaaccttt ttggtcaaaa attttttgtg caatagttat aattagcctt tgtttttctg
    10741 tcactttatt accttctttc atataaaaaa cgtttagtac tatatagtac ctataagttt
    10801 taataaatat attatacatc atttggaaaa aaaatcaata tatacactgt aatatgaaat
    10861 ttttgaaaaa tttattgtta tttttagtcg tataaaaaag aaacttaaga gtttcttaag
    10921 aattgtttaa ataaattgca ataaattagt ggtatgatta tagtatgaaa gagaatgtct
    10981 tgaaattttt ctgtatcaaa ttccaattat ggaggtgtag tatatgaaaa agaaaatttg
    11041 tgtagccata atttttgctc tatttatagt ttttgtagaa atgtttattg atagttctag
    11101 tgaaggaagt aaaattatga cagctgaatt aagtaaatac aggaagggcg taaatgtatt
    11161 atcaataaac aatattatag tagcgaataa aaaatatagt ttacctaaag actattctcc
    11221 tcaggaaagt agtgaagcga gaaatgcttt ttataaaatg aataaagatg ctcaaaaatc
    11281 aggattaaat ttaaaagctt ttagtacata tagaagttat gaataccaag atagattatt
    11341 taagtcatat gtaaaagaac atggagaaaa agaagcaaat agattttcag ctaaacctgg
    11401 agaaagtgag catcaaactg gacttgcttt tgatattggg gggaatgacc agtcttgttg
    11461 ggcaaataaa aagtttaaca atacaaaaga agctaaatgg ttgtatgaaa atgcatataa
    11521 atatggtttt atacttagat atccagaagg caaagagcat ataacaggat atatgtatga
    11581 atcttggcac tatagatatg ttggaactga acatagcaaa aactttgcaa tgaataactt
    11641 gactctagaa gaatatttac atataaatta agagatagtt tgttaaaatt aggttaaaat
    11701 aaaaaataaa ctagactatt aattgtgtaa agtgatataa tgtaaatata atttaagata
    11761 actactcgaa ggggagtagc ttacacgaaa gtggtaatta atcgtcaaga cagtagaaat
    11821 actcggttaa ttagcaaggg attccttgat agcaagacct tcaaaataag cattaggtat
    11881 gtttgttttg gggtcttttt ttattcaagg aatttttatt taaaaaaatt taaatttcaa
    11941 gtatacataa gagcccccaa acataaaata aatttattga agaggagggc aacaaatgtc
    12001 ttacaaaagt acttatcaag aagtaattaa aaatttagac tcaagtttat ctggtttgag
    12061 taaagaaaga gcagaagagt tgttagaaaa aaatggagct aatgaattaa aagaagcaga
    12121 taaggttcct acttataagc ttttcctaga aagttttaaa gacccattag taataattct
    12181 attgatagct gctttagtac aaatattttt aggtgaaaca gtggagtcta taataatttt
    12241 tgcagttatt attataaact ctgttctggg tgttgtacaa acaaaaaaag cagaaagttc
    12301 attagaaagt ttgaaaaatt tatctgcacc aaacgcaaag gtaataagag acaataaaaa
    12361 aatgacaatt ccagcaaaaa atctagtagt tggagatatt gtattcttag aagctggcga
    12421 ttacatacca gcagatggaa gacttataga agcacaaact ctcaaggttg tagaaggtat
    12481 gctaactgga gaatcagaac cagttttaaa gcatacagaa aaaataagtg aagatgtaag
    12541 tttaggtgac cagaaaaata tggtatttag tggctctgta gttgtttatg gtagaggttc
    12601 ttttatagtg accggaacag gtatggatac agaaatgggt aaaatagctg ggcttttaga
    12661 aagtgctgaa aataaactta caccattaca acaaaaaata gaggatttta gtaaaaaact
    12721 tggtgtaggc attgtaatac ttgctctttt aatatttata attcaagtag caagaaatta
    12781 ctttatggtt ggaaatggag aaatgacaca aattatttta gattcattca tgttctctgt
    12841 agcagtagca gtggcagcta taccagaagc tttatcgtca atagtcacta tagtattggc
    12901 tgttggaaca aatagtatgg caaaaaaaca agccataata agaaaattac cagcagtaga
    12961 aactttaggt tcaacaagtg taatatgtac tgataaaaca ggtactctta cacaaaataa
    13021 aatgacagta gttgattatt atatgtatgg aactaataat gatgagttag ataaagaaaa
    13081 agtaaactat tcttatcatg ctaaattatt gactatggtt tctacattgt gtaatgactc
    13141 tcatataact agtgatggta aagaagttgg cgacccaaca gaagtagctt taataaatta
    13201 ctcaagtaaa aatgatttag attatgataa attaagaagt aagtatatta gaataaatga
    13261 aataccattt gactcagata gaaagcttat gtctactgta aatagtatat atggagacta
    13321 tataatgttt acaaaaggtg ctccagatat tgtgtttagt agatgtaaat atgctttgaa
    13381 aaatggttca aaagtagata taacagatga gataatagaa gaatataaac ataaaaatga
    13441 agagttttca aatagagcac ttagagtatt agcttttgca ataaaagatg ttccagaaga
    13501 tgattttgta ccttcaattg atgatgaaca tgacatgaca ttggttggaa taatggcaat
    13561 gatagaccca ccaagagaag aagtaatgga tgcagtaaaa gaggcaaaga gtgctggtat
    13621 aaaaactgtt atgataactg gtgaccataa aacaacagca gcagcaattg caaaagagat
    13681 tggtataatg gaagatggag acctagctct tactggaaaa gagcttgatg ctttgagtga
    13741 agaagagcta tatgaaaaac tagaaaatat aagtgtatat gccagagtct caccagaaaa
    13801 taaaattcgt atagtaaaag catggcaaca taaaaataat ataacagcaa tgactggtga
    13861 tggtgttaat gatgcacctg ccttgaaaca agctgatata ggaatcggta tgggaagtgg
    13921 tactgatgta gcaaaagatg cttctgccat ggtattggtt gatgataact ttgcaagtat
    13981 agtaaatgct gttgaagttg gtagaacagt atacagtaat ataataaaat caattactta
    14041 tctatttgca ggaaacttag gagctatagt atccatatta tttgcagtat ttgctggttg
    14101 gtcaaatcca tttacagctt tacaactttt atttataaac ttagtaaatg actctttacc
    14161 agcaattgca ttagggtttg aaaagtcaga aaaaaatata atgaataaac ctcctagaca
    14221 tccggatgaa agtatactag caggaggaac attgagggca gttgctataa gaggttgtat
    14281 aataggtata gttacaataa ttgcacaata tataggattg caagtatctc cagaacttgg
    14341 agtagcaatg gcattttcaa cattgatatt agctagaata atgcaaacat tacctgcacg
    14401 ttctaataat caaacagtaa taaagttagg tttttttagt aataaatacg ttataggagc
    14461 agttctagtc tgtcttgggc tttattcttt aacactaata ccagtgctaa gaggaatatt
    14521 ctctatacca acaacatttg gattgtatca gttgggaatt tgcttaggtt tagcattgat
    14581 ttcatcaata ttaatggaac ttaacaaatt aataaacaga agtgaagtaa aataaataaa
    14641 aaattaaagg gcatattgat tttaacaata tgccttttat aaatagtcta acttattcta
    14701 tattatcaat tacttggaat gcctttataa cttcaggtaa ttctttttct tcaggcattc
    14761 taaatcttat gaaattttta tcaagtccag taaaatcact tccagatata actcttattt
    14821 ttaatttagc aaactcttgt tgcaaatcta tgtccttgtt cttatgttca actgtcataa
    14881 ttgatacagt atcactagtt tcagctatat taaggttttt ccatggaatt aataattgat
    14941 tttttatatc ttttgttttt tcttttaatt cttctataaa ttggacatca tctaataaat
    15001 tggctgcaat actacgagat atttcagata cttcgtaagg agtagaaatc tttttaatag
    15061 ggttaacaag ttgttctgga agaactgcat atcctgctct tagtcctgct aaaccaaaac
    15121 cttttgaaaa tgtttttaaa gcaattacat tatcataatt atttaaaagc ttaacagctg
    15181 aattttcttt tggcatgtat tcaccataag cttcatctac cataactgct atatcatatt
    15241 tagctgcttc ctttactata ttttcaattg atgataaagg tataatttgt cctgtaggat
    15301 tatttggatt gtctatataa attactttat attctggatt tattttttca ataaattctt
    15361 tttcattaaa cttgaaatta tcctctttct ttaaaagaac atagtcataa gtagcaccat
    15421 gcatttttat atctgtttca tattctgaaa actgaggtga atatcctaaa actttatctc
    15481 ccttttcaat aaataatcta tttaaaaggt aaataacatg tatagaacca tctgccaaac
    15541 aaattctgtc agtgtctaat gttaagaagt ctttccaata atcgactata ttgtctttta
    15601 aagcaattga atgaggatat cctcttatca tatcaaattt taaagcatta aaagcttcta
    15661 cagctttgtt tgagtaagat actgtattta taccttcacc acagtctatc tcgaatacat
    15721 cttctgaatg tccagattct attgcataac tttttttcaa ctgcatttca atagctttgt
    15781 taatttttaa tttcatagtt tatcactcct tatttagtca ataataaatg ttataaaagt
    15841 tgctagattt aaaatattat gaaaatatat aatagtaaaa aatgaatata aatattataa
    15901 tagctcactt tatttaatat gattatatat catatattgt aaaatttcta gcattataag
    15961 actataaatt gaaaatattc agaaaaatac tacaagaaac gatttatttt gctcttaaaa
    16021 taagttaaat gaatgttatt aattttgtaa attgaaatag tttaagtata aagttatgat
    16081 ataatctaat aagggtaatt ctttagatta tattaaggaa atataagtat acaataaaaa
    16141 gttatggagt tggattatgg gatataaatt aattgtaaca gatatggatg gaactttatt
    16201 aggaaataat cataaagtta cagatgaaaa taaaactgca ctacaaaaag ttataaaaaa
    16261 cggtattaat gtaactttag caacaggaag agccttcgat tcagctaaat gcaatgtaga
    16321 ttttcttaaa gaggacatgc caataatagc ttgtaatggt tcattgataa gagagcaaaa
    16381 cggaaacata atatattcaa ataagattga tacaacaact tgtttaaata tcttagatgt
    16441 attagataaa tacgatattt attatcaatg taatagtata gattctatgc tttcaaaaaa
    16501 aatagaagga cgagaagata gattaagtgt atttttaggc tctgagacag aagtaattat
    16561 aagagatgat ttgagagaag aaatttttaa aaaagatata ctaaaatttg taatcataga
    16621 agaaaagaat ccatctattt tggatgaaat aagaaaagaa ttgagaaaag ttcaaggaat
    16681 aaagataacc tcttcatggc caaacaatat tgaagtcatg aatgaaggtg ttgataaagg
    16741 taatgcagtt aaaattttag ctgaaaaaat gaatatagat agagaagata taattgcatt
    16801 tggagataat tacaatgaca tagaaatgat aaaatttgct ggtcttggag tagctatggg
    16861 aaatgcagaa gaattgatta aacaagaagc tgattatgtt acagatacaa atcaagacag
    16921 tggagttgca aaggcaattt ataaattcct agagttaaaa gaatcactta gttcttaaaa
    16981 tgatatataa ttaggaaaaa ataggttgac tattttgtag atagtaatta taatacaaat
    17041 agataaaaca taaaaattta gattcagtga aaaagagagt agatatggag aaaatctcag
    17101 cgaattgggg atggtgtgag cctaatgata acactttata ttgaaaagaa ctttggagaa
    17161 tactacttga aattcagtat ggtagtaggt aatctcgcct taagagaata gagtgggtaa
    17221 acattgtttg ccaactagag tggtaacacg gaatatttcg tctcttggtc tttttgacca
    17281 agagattttt tagtttcatt aagctataag aattataatt aaaatacaaa aaaataaaat
    17341 atgaggtgaa agttatgaaa ttatggggcg gacgctttag aaaagcagaa aatcaactta
    17401 tggaagaatt taataaatct tttggctatg attgtatact gtacaaaaaa gatatcgaag
    17461 gaagtgtagc acatgttcat atgcaagtaa aatgtggact tttaacagaa gaagaaggaa
    17521 agtctataac agaaggatta aaagggatac ttgaagatgt agaaaatgga aagttagcat
    17581 tagatggaga gtatgaagac atacatagtt ttactgagat aaatttaatt caaagaatag
    17641 gagatgttgg aaagaagctt catacagcac gtagtagaaa tgaccaagtt gcagttgata
    17701 tgagattgta tgccaaagaa aaagcaaatg atttggtaga tttaatatct gaatttaaag
    17761 cgactataaa agatgttgct gataaaaacc cggtgatgat gccaggttat actcatcttc
    17821 aaagagcaca agtagtgaca tttaagcatc acttaatggc atattacagt atgtttgata
    17881 gagatgagaa aagaataaaa aatgctatag aaatattaga tgaatctcct ttaggttgtg
    17941 gggctttagc aggaactaca catgatatag acagaagtat aacttgtgaa caattaggct
    18001 ttaaaaaagt agtagataat tttatggatg gagtaagtga tagagattat ttattagaac
    18061 taatgagtga cttttcaatt ataatgatgc acttaagtag attaagtgaa gagttaatac
    18121 tttggagttc acaagaattt ggatttgttg agatagatga tttatataca actggaagta
    18181 gtataatgcc tcagaagaaa aatccagatg gtgcagagct tataagaggt aagactggca
    18241 gagtatatgg aaatttattt ggtcttttta cagtaatgaa aggaatacca ttagcatata
    18301 ataaagacat gcaagaagat aaagaaggtt tcttcgatag tgtacatact cttgaaatgt
    18361 gtatacaaat aatggataga atgatagcta cactaaaggt aaatgaggat aaaatgaaac
    18421 aagcagtaaa gaatggtttt ttaaatgcaa ccgaagttgc agattattta gttaaaaata
    18481 atgttgcttt tagagatgca catggtatag taggaagtat cgttatatat tgtgaagata
    18541 ataaaaaagc aatagaagat ttaacattag aagaattata taagttttca gatgctttta
    18601 aggaagatat ttatgatttt atagactatg agagtatatt aaataaggga ataaaaaaga
    18661 atttaaaata atatacttat ttctaaaagc tgtagatttg aatgttatca ttcaaatcta
    18721 cagcttttta ttgtgtaaaa cttgattata taaaagcaag aaatttaaaa aaagtaatat
    18781 ttaaaataaa tatataaaaa attgttatta aaatgataat taatatcaat aagtattgac
    18841 aaaattattt ttagatacta ttatatataa tataaataat aatgaaaatc aatgtcaatt
    18901 aaatgggagg aaatctaatg aacttattag tgattggtgg tcatgaaaga atggaaaagg
    18961 attatatggt tatggccaag aaaaaaggtt ataagacaaa ggtatatact actatgtcat
    19021 ctaaattaaa taattctata ggaagaccag atgcagttgt catacttaca tcaactgttt
    19081 cacataagat gtctagaacg gttgagtctc aagctaaaaa acaagatata ttaatcgtaa
    19141 ggcataaaaa tagcagtaaa gtagccttta atgaatgttt agatatggtt gatgaatgtc
    19201 tgggaaattg ttcaaaatgt aagcttaaag ataaacaaaa acaaaaaaat atataagtat
    19261 aaaaaataca taaacataaa attaaaggta ctgagataat agttataatt attatctcag
    19321 tacctaattt tataagtaga agtatattat aaaattttta ttataatttc taactaattg
    19381 ctactttttc atatttcttt tacttctagc tttttttctc tttttcctct ttatatttga
    19441 agttattata aataaaacta aaagtactag aatacctgca ataatcttaa caaaagtcat
    19501 tagaatatta tttccagtca aaaatggaat actgctatca agattatttt ttgcaattaa
    19561 gtctatactg ttttccagtt taccattatt atatatattt aaagtaccaa ccttagcacc
    19621 tttttttata ggcaaatcaa ttttatttaa ctctgttttg gtatcatagt tgccttgaga
    19681 ttcatttttt tctaagaata tcctataact atttttgggt tcataaacca attcatgctg
    19741 ttttgtaaat aatacttttt tagtatctgt gtatttttct ttatcaacaa tagtagcaca
    19801 cttaaagtta tcaaatccat aatcaataag aatacgtgag tctaaatata aatcagcatt
    19861 agttgaatta aatacagcaa cgataactct tctgccatct tttacagcac tagataaaag
    19921 acatttacca gcagcatcag tatatccagt ttttatacca tcaactatat catattttat
    19981 atttataggt tgacctttgt atgtaatctt atcatgtgat gtcaaaaact tattagtgtt
    20041 tacaaagtat ctctcataag gatatgcttt tgttgcttca aatttaagtg acttagtttt
    20101 tacaatttgt ctaaaagtat cattattcat agcttctcta gctatgagag ccatatcatg
    20161 agctgttgtg tagtgatttg ggtctggtaa tccatgagga ttattaaaat gagtattagt
    20221 agctccaatt ttttttgcct cagagttcat aaggtcaata aatttttgta catcgccacc
    20281 accaacatat ctagctaata caaaagcagc atcattagca gaatgaacta aaagagcatt
    20341 taataactgc tttacagtaa aagattctcc ttcttttaga tacatactag aaccatctat
    20401 ttgaggtaaa tttttaattt ctattacttg atttaaatct ttaacctcct ttaaaactaa
    20461 acaagctgtc catactttag ttgttgaagc tggataaagc ttagaatttc catccttatt
    20521 atataatatt ttgccagatt catagtccat taaaactgca tgtttagcaa caatagatgg
    20581 ttcattatct gcaaaagaga tattagagct tcctaaaaat gaagtaaata tcaataaaca
    20641 gattaataaa agtgataaat ttcttttcat tgtgagcctc caaattttaa attcatcttt
    20701 tagtatagca tatatttgtc aataattaaa agaaaggagt gattaatata tgaaaaaaaa
    20761 ggtaaaattt atttcatttt ttattttgtt tattttaata atatcatcaa taatcgttta
    20821 taaatcgctt atttttaaag atgatattta tgttgtaagt aaaaaagttt cgtctaatga
    20881 aaaaacacat gctgtagagg cagaaattaa aaatgaagat aatagtcaca ataaagcaac
    20941 taaagatata gataaaaatt ttcaaaacaa taaaataact atatacataa gtggagcagt
    21001 aaatagacca gggattgtaa ctatagagcc agacaagaga ctttatgatg ctgtagaatt
    21061 actaggagga actacaaaag aagccgattt aaatggagtc aatctatcag taagattaga
    21121 agatgagcaa cattacataa tacctaaaat aggtgaagca atatctgtta caagcaatga
    21181 tgattccaat aaatcaaatc aaaaaaatga gtcaagaagt gagcctaaaa ataaatctaa
    21241 taaaaatata tctaacaaat caaaagtaaa tataaatgta gcgactatag aagaattgga
    21301 ttctctacct ggagttggag aagctacagc caataaaatt ttacaacaca gagaagaaaa
    21361 tggacagttt agttcaatcg aggaaataaa aaatgtaaat ggtattggag ataaaaaata
    21421 tgaaaatata aaagatttaa tttgtgtaga ctaaaatata atacaaaaca tacttataga
    21481 tatggtatta taaatatgta tgtatatgtg tgtatatgtg gaaatttagt aaaggaggca
    21541 cttttatgaa aaaagaacaa aaaaaactta cagagatgac aacagcaggt ggttgagccg
    21601 ctaaaatagg gccagaggtt ctggcatcag ttttatctca attgcctaaa aatgataata
    21661 tagaaaattt attagtagga ctagatacag cagatgatgc tgcagtttat aaattaaatg
    21721 atgatatggc acttattcaa actttagact tctttacacc aatggtagat gacccatatg
    21781 tatttggtca aattgctgca tcaaattcac tatcagatgt atatgctatg ggaggcaaac
    21841 ctttggttgc tatgaatatt gtttgttttc catcatgcca tgatatggat gtacttgcag
    21901 aaatattaaa aggcgggttt gctaaagtga aagaaagtgg agcacttttg gttggagggc
    21961 atactgtaga tgataaagaa cctaaatatg gtctttcagt ttctggaatt gtaaatccaa
    22021 ataaagtttt atcaaatgct actgcaaagc ctggtgataa gttaattata acaaaaccaa
    22081 ttggagtggg tgtattaaac acagccatga aagaaggtat ggtagaacaa catatagcag
    22141 ataaagtaat agaaataatg atacatttaa ataaatatgc agcaatgagt tttgataaat
    22201 ttgatgtaaa ttcagttaca gatataactg gttttggtct acttggtcat actttagaaa
    22261 tggccaaagc ttccgaagta agtattgaaa ttgaatcaaa acatgtgcca attattgaag
    22321 gtgcaataga aatggcacaa atgggaatta tacctgctgg tatgtataaa aatatgcatt
    22381 atgtatctaa agatgtagag attgtaggaa atgtagaagt tgcagttcaa gatattttat
    22441 acgacccaca aacatcagga gggctgttaa tttcagtaaa agaagaactt gcagaggagc
    22501 ttgtaaaaga tatgaaatta aatggagcaa tagaagctaa aattataggt tctgtagttc
    22561 caaaagggga aaaatatatt acagttttat aaaatattat agagaaagag tgattatttt
    22621 gagcaaaaga gaattgtttg caatgttgcc ttcagttgat gaagtattaa gtgataatag
    22681 aattgtagaa ataataaatg aatatcctag aagtttagtt ttagaatctg tgagagaagt
    22741 aatagattta aaaagacaat ttatattaag attaaaagaa gatatatcaa attctgtaac
    22801 aatagagttt ggtgaaataa tagaatctgc aatagagaga gtgaagttaa attactcatt
    22861 atctttaaaa aaagttataa atgcaactgg tacagttatt catacaaatt tagggaggtc
    22921 tttacttagt gaagatataa aagatgaatt atggtgtgct gcttcaaggt attcaaactt
    22981 agaatacgat ttagataatg gagaaagagg ttcaaggtac tctcatttaa ctagtacaat
    23041 aaaaagactt acaggagcag aagatgtact agttgtaaat aataatgcag cagcagtact
    23101 tcttgtactt agcacaatgg ctaaaggagg agaagcaatt gtatctcgtg gagaattagt
    23161 tgaagtaggt ggctcattta ggattccaag tataatggct cttagtggtg cagaattagt
    23221 tgaagttggt tcaactaata aaactcacct gaaagattac aaagaggcca ttacagaaga
    23281 tacaaatgtg ctgatgaagg ttcatacaag taactataga atcatgggat tcacagaaag
    23341 tgtttctata gaagagttag ttaatttagg taaaaaatat aaattgcctg taatagaaga
    23401 cttaggaagt ggagtattta tagatttatc aaaatatggt ttatcttatg aaccaactgt
    23461 attagattct attcgacaag gtgcagatgt ggtaactttt agtggagata agatgcttgg
    23521 aggtccacaa gcaggtatta tagttggaaa aaaagaatat atagaaaaaa tgaagaaaaa
    23581 tcaacttact agagccctta gagtcgataa acttacaata tgtgctcttg aagctacatt
    23641 gagaatgtat ttagatgaga caaaagctat agaaaatata cctactttaa aaatgttgac
    23701 gtataaaatt gaagagttag aagtaaaagc aaataaatta tttgaaaaaa taactgcttt
    23761 aaacttaaat gcaaacataa atatagaaga tggattttca caagtgggag gagggtctat
    23821 gcctcttgaa actataagta caaaggtaat agcaataact cctgaacata tgaatgtttc
    23881 atctttagaa aagaaactaa gacttagtga agctcatata atagccagag tgtatgataa
    23941 taaatatgta ctagatgtaa gaactatatt tgatgatgaa tttgatgtaa tagttgatga
    24001 attgagaaaa gcatttaatt aaataaattt gagttaataa atattaaatt tagaagtata
    24061 agtatgaagt tttgattaaa aaatagctac acacacttgt gactttagtc ataggaggtt
    24121 tagagggggc aaaaaatgaa aaatgtagta attggaacag caggtcatat tgaccatgga
    24181 aaaactactc ttataaaagc attgactgga agagagactg atacattaga tgaagaaaaa
    24241 aagagaggta tttcaataaa tttaggattt acttattttg atttaccaaa caatagaaga
    24301 gctggaattg ttgatgtacc aggacacgaa aaatttataa aaaacatgtt agctggagca
    24361 tcaggaattg atatagtttt acttgttgta gcagcagatg aaggggttat gccacagaca
    24421 gttgaacatt tagatatttt aagtttttta aatatcaaaa atggaatagt agttctaact
    24481 aaatctgata ctgtagatga tgaatttaga gagctagtaa aagaagatat ttgtgaaaaa
    24541 ataaaaggaa cttttcttga agatgctgaa ataattgaag ttgattctat atccaaaaga
    24601 ggtatagaca cccttattga aaaaatagat aaaatgagtg atgatataga agataaaaat
    24661 gaaagctctc cagcaagact taatatagac agagtatttt caataaaagg atttgggact
    24721 gtaataacag gtactttaat agaaggaaag ataagtatag aagatgattt ggttatatat
    24781 ccacaggtat taaaaacaaa aataagaagc atacaagttc atggagaaaa taaagataca
    24841 gcttatgcag gtcaaagaac agcaatcaat atatcaaatg taaaagtgga tgatataaaa
    24901 agaggggatg ttttagctgc accaaattca ttagaggaat caatgatgtt agatgtaaaa
    24961 ttatcattgg taaatcattt agataaagga ttaaaacact gggatagatt aagattgtac
    25021 catggaacca gagagatact ttgtagagca gttccactag ataaagaatt aattgaaaat
    25081 ggagaaagtg gctatgttca gttgagactt gaagaaagca tagtatctaa gaaaggcgat
    25141 acatttgtag tgagacgtta ttctccaatg gaaactatag gcggaggtgt aataattgac
    25201 ccatctccta aaaaacataa gaaatttgat gaaaaagtta tagaagcatt aaaaataaaa
    25261 gaaaaaggtg aactaaaaga tataatagaa gagtacttaa aaaggaatct aaaaaattat
    25321 ccaaatataa aagaaataat gagctatagt ggtgctcatg aagaagatgt aaaaaaagcg
    25381 cttgaaacac ttatatcagg agataaagta tttattatag gaaatatgta tatgcatgta
    25441 aatcaataca ataaattaaa agaaaataca ataaagcttt taagtgagta ccataagaaa
    25501 tatagactta gaaaagggat gttaaaagaa gaagtaaggt ctaagataga gagtaatttt
    25561 aagactaggg agatggatat tttattagaa aaattatcta cagaaaatgc tataaaaata
    25621 gaaaataata tagtatcttt attagatttt gaggttattt taaatgagaa gcaaaaagaa
    25681 atagcaaaaa aaatagaaaa aagattaaaa tcatgtggag tttcttctat actgacaata
    25741 gatgaagttt ctgaaggaaa tcataactat gctgaagtat tggagtcaat gataggtaat
    25801 aaagtagaga aattagatga tttgtatata atggacaaag atatttatga aaatgcaaag
    25861 aatactttga taaattatat aaaagaaaat aaagaaataa cattaggaga atacagagat
    25921 ttgattgatt ctagcagaaa aaattgcatg attatattgg aaaacttcga tagaaacaaa
    25981 ataactaaga gagtagaaaa caaaagaatt ttgttttagc agaaaatgtc tgtttttgct
    26041 ttaaggtata aagaaggaat tataatgtcg agtatcgtat aattaattag tataaaatat
    26101 taattaagag gaagtgtaaa gtattgaaga gcataatacc tgatgtaaaa ccagatataa
    26161 aagaaagaga agacatgagc cttttattta taataatggg ctcagtactt ttattattta
    26221 ttataaaaga tacagataaa tatgaaactt tattacatac catatatact atattcttag
    26281 tagctacagg agtaattgta tttaatacta caaaatttaa agtagattca ttttctacat
    26341 ttttaggatt aatttttata gctactggag cattggagtg tatatattta ttcaattcat
    26401 tagaaattaa aactcagttt gtgagagaac ttaacattac aatatcagca ataacagatt
    26461 tatttcctat attgggagta tacttaagtt tcaaatttgt aaaagataat aaacaaattt
    26521 attcaagtat aattttattt atagtaactg ttacattgac aataatatct ttattcataa
    26581 tatctggaat ttgtgaatat ttaggaaatg gtacttcaca atatgcttta gaagttataa
    26641 tatctatatt tataataatt atttctattg ttagtggaat tgaattaaac ttaagttcaa
    26701 gtgaaggtaa atgggaatat aatgaaaaaa agatttttaa cagaataata gtaataataa
    26761 tcttatcaag agttccaaat ctattacata tagttattga tgataggaat atagagagaa
    26821 tattatcaca tataataata aatgtagcta tatattattt atataattac atagtatcta
    26881 agaatattaa gaaaacagca ttagaattac atgacataaa tgaagagtta acactaaaaa
    26941 cggaaagttt gaaagaaaaa aacaaaaagt taatttatga gacagaaaag atagaggaac
    27001 ttaagggaat acttataaaa agagaatcta gactgcaatc tacattagat gtagcagtaa
    27061 atagtatagt tgtatttagt aaagatggag aaattacata tgcaaataaa agctttagaa
    27121 atacttttgg agactataaa gaacaagata aattgactga taaaataaaa aacttcaatg
    27181 atttgataga aagcattaat tatgtgtttg tctatgagaa gaatgtagaa aaacttatta
    27241 gtacaagcga taataaagtc tatcaagcta tatttgcacc tttaattatt gcttcacaaa
    27301 cagaaggagt attgtgtgtt ctggaagata agactaagaa aaaagagtat gaacgcaaac
    27361 ttattgaagc aaataagaga agtagagagt ttttagaaag tattggagat ggcatagtag
    27421 tgcttgaagg taataataaa atatatgtta ataatgcatg tagggaaatt tttaaaaata
    27481 atttagaaag tattgatttt tcattagtat gtaaaagtga agaaagtata gaaaaaagat
    27541 atgtaataga tggtgaagta aagtatgtag agatgagttt ttctcaatat actaatgctg
    27601 gtactgataa aactattatt gtaatacgtg atacaacctc tcgaaaaata tcgcaaataa
    27661 aacttgagga aagtcaatca tcatattcaa gatttataga tatattacct gatggcatat
    27721 gcttattaaa agaagattta agtataaact atgcaaataa gtcgttttta gatatgctag
    27781 cttttacaaa catagatgat ataaaagatt ctaatattaa gctattaatg aatgcgaata
    27841 ctgaagaaaa aatgaaattt actgataata tggctaaagt tttaaatgaa aatagaagta
    27901 tacttttact agagtatgaa ttgataaata gttataatga tatagtagaa gtagaattaa
    27961 gtgcattacc ttttgctata tacaatacta gatatataat gcttattata aaagacttag
    28021 tacataagaa atattccgag caagcggaaa aagaactact tgaaagattt aaaacagata
    28081 aaatcaaaac ggagtttttt gcaaatatgt ctcacgagtt aaaaactcca ctaaatgtta
    28141 tatctagttc gaatcaacta gtagattctt tctatagaag tgaaaagata aaagattaca
    28201 ataataatat taaatctcat gtggatttag ttagacaaag ttcttatagg cttcaaagat
    28261 taataaataa tattatagat ttaacaaaga tggagtctgg attctatacg ttaaaacttg
    28321 ctaaatacaa tattgtatct gtaatagaag acttatttat gaatatagaa gagtacgcac
    28381 ttagaaaaga tataaaaatt ctttttgata cagaacttga agaaattaat atttatatag
    28441 acaaggttga aattgagaga attatgttga atctattatc aaactgtatt aagtttactg
    28501 ataatggagg ctggatatat gtaagtattc attataaaat agataaagta atcataagtg
    28561 taaaagatac tggagttgga ataccacaag ataaattaga actgattttt gaagaatttt
    28621 cacaagttga taagacttta tctagaaata ctgaaggaag tggaataggg cttgctatag
    28681 ttaagaatct agtaagtctt catggtggag atatagaggt aataagtgaa gtgaacaaag
    28741 gcacagagtt cttaatttca cttccaatga agggatttag tagtgaacat tacacagaag
    28801 ataagagaat atataatatt caagaaaaaa taaaaataga attttctgat atatactatt
    28861 agaagtgatt atgagtaaaa ataaaataaa aatactatct atttaaatat ttaagctata
    28921 agaaataggc tatcataaga taaattatta tgatagctta tttttagtta ggctttatat
    28981 ctatatgtga gaacatataa tctctaaatt accttcaaaa ccaaattctc caaagttgtt
    29041 tggtagtata aaatgcatac ccttttttaa attgtattct acagcattgt gtataagttt
    29101 tccatttcca tccaatacac tgtataaaga aaaaggtgtc ttgtgtgtaa aagtacactt
    29161 tccaaaaata tctaatttat aaacgctaaa aaattcattt gatacaaatg ttgtgcatct
    29221 aaagtctgat gttgacacaa ttttatagtc agtatcaaaa tttatatgag gaacattggt
    29281 aacatctatt gatttttgaa cgtgaagttc acgtttatta cctaaattgt cagttctatc
    29341 ataatcataa actctataag tagtatctga attttgttga gtttctaaaa ttaatgttcc
    29401 tttacatata gcatgtatag taccacttgg aacatagaaa aagtctccct tttttatatt
    29461 aacctttcta agtagtttgt cccattcatt gttatttacc atatccacaa attctttatg
    29521 agattttgca ttatgaccta ttataatttc tgcatcatca gaacaatcta ttacatacca
    29581 acactctgtc ttacctaact ctccattttc atttttttta gcatattcat catttggatg
    29641 aacttgaact gataaattat catttgcatc caatattttt gtaagtaaag gaaatttatc
    29701 tccaggtgtg tttccaaata attctctatt tttatcccac aattcagata gttttttacc
    29761 tttatagatt ccattttcta ttaagcaatc tccattttta tgagaactta tagcccaaca
    29821 ttcacctgtt gttggcgaat ctatttcata attaaattta tctttaagtg cagtaccacc
    29881 ccatattcta tccataaaaa taggttttaa aaataatggt tccataatcc tgttcctcct
    29941 atgatattaa atttatccta caaataatta tatataaata cattataaaa tcaatagtaa
    30001 aaaagttttg tcccttgaaa tgacataaag tataaggagt tattaaataa gataaactat
    30061 gatatataat ataaagttct aaattggagt gataattatg gaattgttta aggaagaaat
    30121 caaaaaatac gaaaaagaat ttttgaaatt attggaagaa tgggtgagca taccttcatt
    30181 ttatgataga aaaactgtat ctaaagatat gccttttgga aaaggggtat atgatgcatt
    30241 aaactggttt gaaaatctag gtagagaaaa caatttcaaa gtgaaaaata tagataatca
    30301 tgctgttcaa attgaatatg gaaatggcaa agagtatgta gatatatttg gacattgtga
    30361 tgttgtaaat ccaggtgaag gatgggatag tgaacctttt aaattaaata ttataggtga
    30421 taaattagtt gctagaggtg tatctgataa taaaggacct atgatagtga attttttagc
    30481 actaaaaatg ataaaggatt tagatattaa tttaaaaagg aaggttagat taatagctgg
    30541 aggaaatgaa gagagtggat ttaagtgtat aaagcattat tatagcaaag agccatatgg
    30601 ggtatgtgga tttactccag atgctaaatt tcctgtatta aatggggaaa aaggtggagc
    30661 aataataaag ttgctttcaa atatagacga taaatcttta tacataagtg gtggaataga
    30721 gtttaataca ataccagata aagtttatat aaagaatata gaaaaattgg gtaaagataa
    30781 tatatgtttt gatattaaca agatatcgat aagttatgat aatgacaatt atattgtgca
    30841 tggaaaaggt ggacattcat ctaaacccga aaaatcaata aatcctatat tagctacaat
    30901 taaacttttg tcagaaaata ttgatgaaaa atggacaaaa gatttgtata agttgataaa
    30961 tcaagataat ataaatggaa atttatttgg tttaaatatt gaaggaaaat gtgggatttt
    31021 atcaatggtg ccaacaataa taaatatagt agacggaaaa ttagaagtag ttttaagcgc
    31081 tagatatcca gaaatattaa gcattgaaga gataatgaaa aaatttaatt tgtatatgga
    31141 gaaaaataat attaataaat ttgagcttat tggggaaaat ttaaagcaag caaattatat
    31201 agataaaaat tcaaaactcg taaaaagttt gcatgatata tatataaagt attctggaga
    31261 tttaaaaaat gatgttagag taactagtgc aggaagttat gcttctgaaa tgaataattc
    31321 agtaatattt ggttgtgaat ttcctgatgg tagctttggt aatgtccatg gtgcgaatga
    31381 atttgctagc ttagatagat ttataactgc aataggtata tatgcagagg caataattac
    31441 attatgcaac aaaatataaa tacaaaatgt cccttatata gacatattat atatacaatt
    31501 aaaattttac ttgatatata attgaaatca aagagaaggt gatacaatga taactaagaa
    31561 acatgcaata atagtaaaga gtttaagcaa taaagatgga tatatgacat caaatgaatt
    31621 ggctatcaaa ttggatgtgt ctactaaaac tattaaaaga tatatagcag atttaaatag
    31681 tgttttaagc aagtatgatt tggtaataga ttcttctaga ggtataggat ataagttaag
    31741 cggttctaaa aacaatatag ccagagctat caaagaagca aataaatata ttgatggttt
    31801 tttagatgat tctgaagagt caagaatgtc aaatataata tgcatgctta ttaatagaaa
    31861 ttatatgagt atagaagcaa tggcagaaga attaaatcta agtatagccg ctataaataa
    31921 attgtctagt aagcttaaaa gaaaacttga aaagtatgac ttagttataa aatctaaacc
    31981 ttactatgga agctatatac atggtgaaga aattaatata aggcaattaa ttactgacta
    32041 tgcaataaaa ttagatgaaa aaagtaaagt gaaggtgttt ttagatgaca ttagtgaaaa
    32101 cgatatatac tgtatagaaa gtattttaga aaaacactta agagaaaaag atacaataat
    32161 ttcagataaa gattttaatc ttttgctttc aaaaataatc gtttctgtat ttaggagtaa
    32221 gagaggtcat agtaacaata taaacttaat ggatacaagt tatagatttc ataactacta
    32281 ctttatagaa agtctaatga aagaaatatc tgataaaatt ggatttaaac ttattgaaga
    32341 tgaagtaatt tatatttcaa attattctgg tgtaatagcc tgtaaaggta cacaaggaat
    32401 aaaaaacaca agtgagcttg aggagcgaat aaatagtgtt atgagcagtg ctcttcaaga
    32461 tatattcctt atttcgggca gtgattatac aaaagatgat gagtttatgg ttgcaatatc
    32521 tgaccatata aaaagatttt taaatagggc tagagctaat gtaaaatcaa ataatccttt
    32581 acttcatcaa ataaaagaga agtttcctat agcttttaat ttagccgtgt ttttatcaaa
    32641 taaactagaa actgagttta atttaaaact tgatgaagat gagcttggat atatagctat
    32701 tcactttgct gcttcaaatg aaagaatgaa aaaaaatact agtaagaaaa tttgtatagt
    32761 ttgtcattat ggtataggaa caggacaact tatttctgaa aagctaaaac agaatataag
    32821 tgatttaagt gttgtaggtg tttatccagt tagatatctc gatatggcta taagtcaaga
    32881 tgtcgattta atagtatcta ctgtcgaatt aaaaggatat gaaaaacctg tcttatatat
    32941 agaaaatata tttgatgata gcttaattga aaacgtaaac aaagcttttt atgaaaagga
    33001 agaaagaaga aagataataa gtaacatgtt tgatgaaaaa gcttttttca atataaaggc
    33061 taatactaaa gaagaggtca tactttcact ttcaaataaa ctaaaagaaa gagactttat
    33121 agaggaaagt tctataaaaa gcataataga tagagaaaat atttcatcaa ctgaaatagg
    33181 aaatctagta gcaatacctc acacaatagt gaagggagat aaaaaatcta taataggagt
    33241 tggaatactt gaaaatccaa taatttggga taagcaagag gttcagctag tatttatggt
    33301 attttttaat actaaaaact tactaaattt ctgattatct tttcataagt tggtaaatgc
    33361 cgatatatcc cgtattttag ggctttatcg gtattttctt ttcggaagat accttgcata
    33421 agctggcatt taccagcatg aaaatgcaac caaaagtagt aaatgagtag taaatataag
    33481 ctccgatatt aacaagccag tctttccagt tctgcttttg cagattgaaa tgtaccgtgt
    33541 gcgtaatagc caagtgtcat ggttatgtta gcgtgtccca tgaggtattg cagagtgttt
    33601 gggttcattc ctctgtttgc catattcgta caataagtat gtctgaatga atgtggcgtg
    33661 atgttcggta acttgtccgt gtgatacttg ttatacttct taatcagtcc tcgcaccatg
    33721 ccctcatagt ttcctgcaac tttaggcaag ccctcacgat ttaggaatag gaaattgctg
    33781 taaccaccta caatcagcgg ttgtgccttt cctctgttct ttagtattct ttggattgct
    33841 tgataagccc gttctgtcaa tggaagttcc cgttttccgt ttttggtctt tggcgtttca
    33901 atatagtaac ccatttcgct atctttcaat aactggtggt ctatattgag tactctgttc
    33961 tgcatatcaa tatgcgtcgt cagtccgcaa aattcagaaa tacgaagtcc cgtttccagc
    34021 agaagcacaa cctcatcata atacttacta taaattttgt ccttttccat aaaggcaagc
    34081 aggcgttctt cctgctctgg tgtaaggata actttctgtt cggtatcatc ttccagaaca
    34141 tcacttagct taaattcaaa tgggttcttt ctgatacagt cgtcttgtat cgccatgtaa
    34201 aatgacgctt tcaaggaacg cttatagtta tcaatcgttt tataggcata tcctttttca
    34261 ctcattctaa tagcccattc tttagcgtcc gactgcttaa ccgtatcaat cgccctcata
    34321 cccaatgggt catttttcag agcgttcata agatactgtc gtcctttttc agtagccctt
    34381 ttgatgttct ttctttggct gttcttcttg tcgtagagct ggcagactgt cattttaccg
    34441 ccgactgtgt cgataccgtc gttaaggtct ttttttatct gtgcttcttt ttccctcaac
    34501 gatatatcat cacgctttcc agcaggtgtc ttgtctgtcg gtacaagttt ccaagaatag
    34561 ataaattgtg gctttccgta tatatcggta tatttataaa cgtatcttcc gtcttttcgc
    34621 tggctctctc cattacgcaa attgcgattt ttactgtctt ttcgtttcac attagacata
    34681 gtgtaaagct cctttccgtc atggaatgag ccgtgatacg ctatacctta ttataccata
    34741 tctacggctc aatgacatta gatttcgtcc aatgtatcta tgattttttc aaattgtttt
    34801 cgcttaatct gaatacgatt accgttcacg ataacccagc cagcgtcaag attttcttcg
    34861 gctaatttac gcaatttctt ttcgccaata cggaagtatt tagacgcttc ttcaatcgtc
    34921 agcgtatatt tttcccagat aggcacatca gtattgttca taatctatac acccccttta
    34981 ctgtgtgtcg ttttttacaa gcaggcagac ggctttggaa agctccgtta gtatctcaac
    35041 tattcccatt cttgtgggca gaaccgcacc atgcggacgt atcattattc tgtgaggata
    35101 ggtcgtggca aaacgacttt tccaacagtc gctctcggat cactgcgtgg gtcgctcgct
    35161 ttctttttga aaaggtcgtg gcgtacagtc cccgtggctc gctatctcac aaacgtatct
    35221 gtctgcttta ttcagttgtc aaagagctgt ggcgaaagcg tgttgctttc atgtaaaagc
    35281 aggagcagag caggaaagag gggattgaac aaatcatgct ctgcggttac tgcttcttat
    35341 tcttcggttt ctaaaggaat atcaaagtcc aacatcattt tgataagtgc ttctctgata
    35401 cgtcccttta attccatgtc tacgactatg cagacattac catatctgtc atagaatgga
    35461 cgtaaacaac attttgatat gtacgggtca taaaatgcca gtatcttttc aatcgaattt
    35521 acgttgccgt ccacagccga cgagataagg taaaatgacg ggcgtgtgtt attcatcatt
    35581 catgttctcc tttaactttt tcttgatttc ttcaagtgag ttcttcctac tgcggaacga
    35641 cgttgaacgg ttaatcttta atctgtcgcc gatttctgta tcgctcatgc ctaagaagaa
    35701 gtacatcaac aagatttctc tgtccttttc agacagatac ttaatcgctt ctgctaaatc
    35761 atcatcaagg acacgaacct caataccgca tacatcaaag gcggtataat cgctttcata
    35821 ttcgtcccag acagccagct tttccacgac gatttctgga agttcacaat aggaaatttc
    35881 cttatttctt cgtcgcttta attctttgcg gtaattacgg acaatgccct ttactacacg
    35941 tttgagcttg caatcgaatt gacattgtat cgttctttgg aagttcgacg gtttcatatc
    36001 atcacacccc ctttccgtta tgacgtgaaa agtgtttatc cctctttccg caccatatct
    36061 gtacggcaag gtgtgatttg ttgcaggaat ttgaaaaaaa ttgaaaaaat tttttcgggt
    36121 acaaaaaaag cccgcacaaa acatatagtt ttatacgagc tattaaagct gtaaaatatt
    36181 cagtttttaa taaaatgcta ttaggtagtg tatgattgta tagaatttcg cttaaaatgt
    36241 tccataatac aatccccctt acagcacttg ttttgtatta cacttttgtc ttttgggtaa
    36301 tcttgtaaat atattcttct gatgtagggc gtttatttcc aaaatacttt ttaaaatttg
    36361 cctgcacctc tgggtcggtg ctgttcatag cttcatcaat cgttgcttca atatccgccc
    36421 gaacatcaga caatgataca ccgccagctt ttgccccagc tttcaatgct tttttaatat
    36481 ctcgtttttt cagaccaatc atatgtgtgt ttctccttta agcataaaca tcttgaaaag
    36541 caagttatga tattgtaaat cattgaaaat ttaatgtttc tgctcttata atactatttt
    36601 tctattctat atcagttttt ctatacgatt atacagacca ccccagactt tcttgttgaa
    36661 tagaatataa tttgtgatat agcccttttc tttccataag ctcattatgt gttccatgtt
    36721 caactatttt tccattttcc attactaata tctggtctgc atctaccaca gtccttagac
    36781 ggtgtgcaat cataataact gttttacctt ttatcagatg tgcaagtgct ttttgtacga
    36841 aaacttcatt ttctgggtca agagaggcgg ttgcctcgtc taaaagaata atcggagagt
    36901 cttttaataa agctcttgca atagaaattc tttgacgttc tccacctgac aatgtacttc
    36961 cgttttctcc taaaatagta tcatatccat ttggcagatt acgaacaaat tcatcacagt
    37021 aagctacttt ggcagcttta tatacttgtt cttttgtagc attaggattt cccatttgaa
    37081 tattattaaa aactgtatca ttaaacaatg taacatcttg aaagacaaag gacatctttt
    37141 ccattaaatt ttcaggattg attgttttaa tgtttttatt accaatcgtt attgaaccgc
    37201 tttgtatatc ccaaaatctg gcaatcaatt ttgcgattgt actttttccg cttccagacg
    37261 gaccaactaa cgctgttatg cttccctgtg gtattgtgca tgaaacattg tgaataacat
    37321 cttcattgtt ataagcaaaa gatacatcat ttaacttaat attataagtt tgaggtgttt
    37381 cttctttccc actcatagca ggagtagtca ataatgtttt cattctttct gtaacgacat
    37441 taagatttaa taatgtagtt aattgagata aaatagctaa tatcggtcca tatatctttg
    37501 ttacaatcaa gaaaaacata agaagaggta atagctcaat ttgtccattg actaataaga
    37561 ttgtccctac aaatatagtt attcctattc ctgcttgtaa aatcatgctt gcactggaca
    37621 taaaaatacc gacaaccatt tcaactttaa cagcaatttt tttcatttcc aataacgctc
    37681 tgttcaaagt cctaaagtga acgccgctta aattacatga tttaatgatt tttattccct
    37741 ctaaatattc ttgtacttga ctggacgcat ttaattttgt ttccacttgc ttttcaaata
    37801 attttatctg atatttcctg ctacaccaaa taactaagaa agcaatcggt aatgtaatga
    37861 aaacgcataa tgctaaacgc caatcaaata gtgcaagaag aacacaggtt aaagttacag
    37921 aaattccatt tgcaattaga ggcggaatag tactacttaa cattgactcc atactactac
    37981 aatccgacat catatttgtt gtaagttctg ataaatcctt tgtgttgaag aaactcatag
    38041 gaagtttacg cagatgttca gcaatacgca atctagtaac atttgactct ttataagaag
    38101 caatataagt cttgcgataa tcatttttgg aagctaagaa aacaatgatt gctgaaataa
    38161 tacctgctcc ccaaagcaac cagatatttt gccaatctaa ctcttgccct aaaaaaggat
    38221 ttaatagctc actaaaaacc ataactgtaa tacaaaacgg aagtaacatt gctaaatttg
    38281 taatcgtaca agcaatgatt gcttttttca aatcagtata gcctttatct gataaaaata
    38341 atatttcttt taattttttc attttactgc accacctttg tttgaacttt caaatcaatc
    38401 gcctctgtat aatgtttcca catttcagca taacgtccat ttttttaaaa aaaacacgag
    38461 tagttgccta ctgtcgagtt tctacaggca gtgatgaaca acttgtcagc ttgcaagcac
    38521 aaaaggccca ttatgagagc tatataaagg ctaatccaga atgggaatac gcaggcttat
    38581 attatgacga gggtatcagc ggcacgaaaa aggaaaaccg ctctgaccta cttagaatgt
    38641 tatcagactg tgaaactggg agaattgact taattattac aaagtcaatt agccgatttg
    38701 ccagaaatac tacagattgc ttggagatgg ttcgaaaact gatcgacctt ggggttcata
    38761 tctattttga gaaggaaaac atcaatacga gttcaatgga gagcgaattg atgctctcca
    38821 ttttaagtgg gcttgcagaa agtgagtcaa tttccatttc cgaaaatacg aagtgggcca
    38881 ttcaaagacg attccaaaac ggaaccttta aaatttccta cccaccatat gggtatcaaa
    38941 acattgacgg tcagatgata ataaacccca agcaagctga aattgtgaag tatatttttg
    39001 cagaggtatt atcgggcaaa ggcacacaga aagttgcaaa tgatcttaat caaaagggta
    39061 tcccttcaaa aagaggtggt cgttggacag ctactacgat tagagggatt ctgaccaatg
    39121 aaaaatatac tggcgatgtt attttgcaaa agacttatac tgatagccat tttaacaggc
    39181 acaccaatta tggtgaaaaa aatatgtatc tagtagaaaa ccaccatgag gcaattatca
    39241 gccctgaaga ttttgaagct gtagatgcca ttctcaatca gagagccaag gaaaaaggaa
    39301 tcgaaaaacg caacagtaaa tatctaaacc gatattcctt ttctagcaaa attatctgct
    39361 cggaatgtgg cagtaccttt aaaagacgga ttcattcatc tggtacaaga aaatacattg
    39421 cttggtgctg cagtaagcat atcagcaata taacggaatg ttccatgcag ttcattcgag
    39481 atgaagatat aaagactgca tttgttacga tgatgaataa actcatattc ggtcagaagt
    39541 ttatattaag accacttttt catgggttac gtaaccaaaa caatgcagcg agttttcgta
    39601 gaattgaaga gttggaaact aaaattgaaa acaacatgga gcagagccaa gtactgacag
    39661 gtttaatggc caaagggtat ctggaacctg ctctgtttaa taaagaaaag aatgcactgg
    39721 aggcagaaag agaaaggctt cttgccgaaa aggatcaact tactcgttcc gtcaatggca
    39781 attttgctaa agtagatgaa gttgaccgtc tgcttaagtt tgccactaag tccaaaatgc
    39841 tcacagctta tgaggatgag ttgtttgaag attacgtaga gaggattatt gtcttttcac
    39901 gggaggaagt aggttttgaa ttaaaatgtg gaatcacatt gaaggaaagg ttggtgaatt
    39961 agatgggtca cacaccctat ggatatagaa ttgaagatgg aaaagctgtt gtggatgaaa
    40021 agacttctga gcaggtaaaa gaattatttt ccggatactt ggcaggcctt tctttgaagg
    40081 aagctgctaa aaaagctggg atagattgtt atcatgccac agcaggtaag atgttgcaga
    40141 acaagcacta cctaggcgat gaattttacc ctcccattat tgatgaggag acatttgaaa
    40201 aagccagaga agaaaaacga aaacgagcag aaaagctcgg gaggataagg gaacctaaag
    40261 atgaaccgaa aacggattac cctgtaaagt tcaaagcaaa acctctggtg caaaaatatg
    40321 aagacccata caagcaggcg gaatatgcct acagtttgat agaaagtgag gtgtaacaag
    40381 tggcagtgag tagaaatgtc acagtgattc cggcaattaa acgagtcgga aataataaaa
    40441 ctagtgagag caaacccaaa atacgagtgg ctgcttactg tcgtgtttca acggatagtg
    40501 aggagcaggc ttcaagttat gaaattcaga ttgaacatta tacaaactat attaagaaaa
    40561 acaaggaatg ggaattggca gggatttttg cggatgatgg tatcacaggt acaaatacca
    40621 aaaagcgtga agagttcaac cgcatgattg aggaatgtat ggcaggaaaa atagacatga
    40681 tcattacaaa atccatcagc cgatttgcca gaaacacgtt agactgcctt aaatacatcc
    40741 gtcagttaaa agataaaaac atcgctgtat tctttgaaaa agaaaatatc aacaccatgg
    40801 attccaaggg tgaaattatg ctgactatta tggcttccct tgcccaacag gaaagccaat
    40861 ccttaagtca gaacgttaag ctgggcattc agtatcgata tcaacaaggt gaagtccagg
    40921 tcaaccataa gcgtttcctt ggatacacca aggatgaaaa caagcaacta gtcatcgacc
    40981 ccgagggtgc agaggttgtt aaacggattt atagagagta ccttgaagga gctagtcttt
    41041 tacaaatatc aagaggacta gaagcagacg gtattcttac agcggcaggc aaagccaaat
    41101 ggagaccaga aacactaaaa aagatattgc agaatgaaaa gtacatcggt gatgcccttc
    41161 tacaaaagac atatacggtt gatttccttt ctaaaaagcg ggtcaagaat aacggcatcg
    41221 ttccccagta ttatgtagaa aacagccatg agccgattat tccaagggag ctttttatgc
    41281 aagttcaaga agagatggtt cgaagagcaa atcttcgtgg ccgcaaaggc ggtaaaaagc
    41341 gagtctatag cagcaagtat gctttatcga gtattgttta ctgcggacac tgcggcgata
    41401 tttaccgacg ggtacattgg aataacagag gctacaagtc tattgtttgg agatgtgtta
    41461 gccgattgga ggaaaaaggg tctgaatgca ctgctcctac cataaacgag gaaacattgc
    41521 agacagcagt ggtcaaggct attaacgagc ttttggctaa caaagaaccc ttcctctcaa
    41581 ccttgcagaa aaacatagct actgtattta atgaagaaaa tgataatgcc accgatgata
    41641 ttgaaggcaa attggaagaa ttacaacaac agcttcttat acaagcaaag tccaagaatg
    41701 actatgaaga tgtggctgat gaaatttacc gccttcgaga attgaagcaa aatgcacttg
    41761 cagagaatgc agagcgtgaa ggaaaaaggc aacgaatcgc tgaaatgact gatttcttaa
    41821 atgaacaatc ctgcgagttg gaggaatatg atgagcaatt agtaaggcgg cttattgaaa
    41881 aagttacggt atttgatgat aagctcactg ttgaatttaa atcaggtgtt gaaatagata
    41941 ttgagatata ggatatcaga aatggcgacc aattgagagg tgttacttcc ttgattggtg
    42001 gcttttctta tttacggatt gactttgact gtgaatatac gtataataat atcaacaatg
    42061 ttgttgatat tattattaat aaggagtgga caacatgatt gatgtaaatg agctatttta
    42121 gcaaaatgaa tggtaattta aaggctattg aaaagacttc atctaatcag cagaggtata
    42181 aaaagacaat tgataagttt taactatctt ttgtgaaatt aaaaaaatta taaatatgtt
    42241 gagtagaagc aaaagatttg gcttggaatt tttacagcag tgaatcgata aaaggagcat
    42301 gcttgatggt agataatatt attaaatcag tagcagagaa attatcctct ctgtcttata
    42361 tagaaggtat tgttttaggt ggttcacgtg caaggggcac ccatacagag gattcggata
    42421 tagatatcgg catctattac aattcagaat catttgacat aaatactatt aatcaattcg
    42481 ctacaaagct ggatgatgag catagaaata accttgttgt acctcccgga gcatggggtg
    42541 attggattaa tggcggcgga tggttagtca taaacgggta tcatgtggat ttaattttac
    42601 gtgatattaa acgtgtggaa caaataatga aagatacaga gcacggaatt gttactgcca
    42661 attatcagac tgggcatccc catggttata ttagtgcaat gtatcgagga gaattagcga
    42721 ttagcaaaat actatatgct aagaatgaaa gcttatgcga attaaaaaaa caggcagaaa
    42781 cttatcccaa tgctttgcag aaaagtttag ttaacttttt tatgtttgaa gcagggttct
    42841 ctttaatgtt tgtaaaagca aattcgggaa cagacgataa atattatatt gcgggtcatg
    42901 tttttcgtat agtttcatgt ttaaatcaag tgttatttgc atgtaataat gcttattgta
    42961 tcaacgaaaa gaaagctata aaactgcttg aaacttttga acataaacct gaaaaatata
    43021 ccgagaaggt aaatcatatt tttgaagtac tcggtatctc actttttgaa tgctacgaca
    43081 tgaccgagaa gctttataat gaagtgaatg aaattgtatc ggagataaat aactttttaa
    43141 acgaggagag ttcagatgaa agaaaacaaa tatgatgata atatattttt tcaaaaatac
    43201 agtcaaatga gtcgctcgca gaaaggactg gctggtgcgg gagaatggga gactttgaaa
    43261 aagatgctac ctgattttaa gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg
    43321 cactgtatat atgcgatgga aaacggtgct tcctctgtag taggtgttga tatttctcat
    43381 aaaatgctcg aagtagcaaa aggaaaaacc cattttccac agattgaata tgaatgctgt
    43441 gccatagaag atgtggattt cccagaggag agctttgatg taatactaag ttcgcttgcg
    43501 tttcattatg tagcagacta tgagaattta ataaaaaaga tatataggat gctgaaggct
    43561 ggtggcaatt tagtttttac agttgaacat cctgttttta ctgctcatgg aacacaagac
    43621 tggtattata acgaaaaagg agaaatactg catttcccgg tggacaatta ttattatgag
    43681 ggcaaacgga cagctatgtt tttggaagaa aaggttacaa aatatcatag aacactgacc
    43741 acatatctaa atacactgct ttcaaatagt tttataataa atcagattgt ggagccacag
    43801 ccgccagaga acatgatgga tattccgggg atggcggatg aaatgcgacg cccaatgatg
    43861 ctgattgtat cggcaaaaaa gaagatgtaa taatatagaa aaaataaacg aggagtatgt
    43921 aaatgagatc agaaaaagaa atgatggatt tagtactttc tttagcagaa caggatgaac
    43981 gtattcgaat tgtgaccctt gaggggtcac gcgcaaatat taatatacct aaagatgaat
    44041 ttcaggatta tgatattaca tattttgtaa gtgatataga accgtttata tctaatgatg
    44101 actggcttaa tcaatttggg aatattataa tgatgcaaaa accggaggat atggaactat
    44161 tcccggctga agagaaaggc tactcctata taatactttt tgatgattat aataaaatag
    44221 accttacctt attgcccctg gaagagttgg gaaactacct gaatgacgat aaattgataa
    44281 agattattct ggataaggat ggaaggattc agcaagctgt agttccgacc gacatggatt
    44341 atcatataag aaaacccagt gcccgggaat acgatgactg ctgcaatgaa ttctggaaca
    44401 ccactaccta tgtggttaag ggactgtgcc gtaaggaaat tttatttgct attgatcatt
    44461 ttaatcagat tgttcgccat gagctgctga gaatgatatc atggaaggtc ggcatcgaaa
    44521 caggctttaa attaagtgta ggcaagaact ataagtttat tgaaaggtat atatccgagg
    44581 atttgtggga gaaacttttg tccacctacc ggatggattc ctatgaaaac atatgggaag
    44641 cattatttct atgccatcaa ttgttcaggg cggtatccgg tgaggtggcg gaaaggcttc
    44701 attatgccta tccggagtat gataggaata taacaaaata taccagggac atgtataaaa
    44761 aatacactgg taaaaccggc tgcctggata gcacatatgc cgctgatata gaagagaggc
    44821 gggaacagtg attacagaaa tgaaagcagg gcacctgaaa gatatcgata aacccagcga
    44881 accatttgag gtgataggta agattatacc gaggtatgaa aacgagaatt ggacctttac
    44941 agaattactc tatgaagcgc catatttaaa aagctaccaa gacgaagagg atgaagagga
    45001 tgaggaggca gattgccttg aatatattga caatactgat aagataatat atctttacta
    45061 ccaagacgat aaatgcgtcg gaaaagttaa actgcgaaaa aattggaacc ggtacgctta
    45121 tatagaagat atcgccgtat gtaaggattt cagggggcaa ggcataggca gcgcgcttat
    45181 caatatatct atagaatggg caaagcataa aaacttgcat ggactaatgc ttgaaaccca
    45241 ggacaataac cttatagctt gtaaattcta tcataattgt ggtttcaaaa tcggctccgt
    45301 cgatactatg ttatacgcca actttgaaaa caactttgaa aaagctgttt tctggtattt
    45361 aaggttttag aatgcaagga acagtgaatt ggagttcgtc ttgttataat tagcttcttg
    45421 gggtatcttt aaatactgta gaaaagagga aggaaataat aaatggctaa aatgagaata
    45481 tcaccggaat tgaaaaaact gatcgaaaaa taccgctgcg taaaagatac ggaaggaatg
    45541 tctcctgcta aggtatataa gctggtggga gaaaatgaaa acctatattt aaaaatgacg
    45601 gacagccggt ataaagggac cacctatgat gtggaacggg aaaaggacat gatgctatgg
    45661 ctggaaggaa agctgcctgt tccaaaggtc ctgcactttg aacggcatga tggctggagc
    45721 aatctgctca tgagtgaggc cgatggcgtc ctttgctcgg aagagtatga agatgaacaa
    45781 agccctgaaa agattatcga gctgtatgcg gagtgcatca ggctctttca ctccatcgac
    45841 atatcggatt gtccctatac gaatagctta gacagccgct tagccgaatt ggattactta
    45901 ctgaataacg atctggccga tgtggattgc gaaaactggg aagaagacac tccatttaaa
    45961 gatccgcgcg agctgtatga ttttttaaag acggaaaagc ccgaagagga acttgtcttt
    46021 tcccacggcg acctgggaga cagcaacatc tttgtgaaag atggcaaagt aagtggcttt
    46081 attgatcttg ggagaagcgg cagggcggac aagtggtatg acattgcctt ctgcgtccgg
    46141 tcgatcaggg aggatatcgg ggaagaacag tatgtcgagc tattttttga cttactgggg
    46201 atcaagcctg attgggagaa aataaaatat tatattttac tggatgaatt gttttagtac
    46261 ctagatttag atgtctaaaa agctttaact acaagctttt tagacatcta atcttttctg
    46321 aagtacatcc gcaactgtcc atactctgat gttttatatc ttttctaaaa gttcgctaga
    46381 tagagttcta tattagagat gtaaagagtt ttggtgaaga ggtttgtgag tatggctttt
    46441 ataaccaggg tgcaatgaga agcactaaca gcagctagct taagaacgca taggatatac
    46501 tttttatgga agtcacagag gaggaataaa atttgaacag gattaacaga gtaacctcta
    46561 ttcttattca gctgcaatca aaaaaaataa ttcctgccaa agaaattgca cagcgattta
    46621 atataagctt aaggacagtt tacagagata tccggacact tgaagaagcc ggaataccaa
    46681 ttggatctga ggccggaaaa ggatattttc ttgtagaggg cttcctactt ccgccggtaa
    46741 tgtttacagc ggcggaagtg ggtgcattga ttacagcagg gaaattttta aattgccatg
    46801 gagatgaatc atttataaag gattttgatt cagctatgta taaaatcaaa tctattttga
    46861 agcatggtga aaaaaactat gcacaggagt tggagaacag tattaacgtg tacagcacat
    46921 ctggacagaa aaatacattg gcggataacg ttattgcagc aattcagact gcaatctgca
    46981 ataaaagggt aatatcaatt caatatcctg catcaggagg gcaagaaccg gaaagcagaa
    47041 tgatagagcc tatatcactg gggttttatg aacagaactg gtacttaatc ggttttgcag
    47101 gctaagaaat gaatatagga attttcgtgt ggatcggatt aaaagcattt gcatagaaga
    47161 agagctctgt caaagccatg atggctcttt ggaacaaata ttaaaacaaa tgctttcata
    47221 taaaaaacta tataatgtaa ttcttagagc tgaaaaaggg gagacataca attctatcaa
    47281 gaacaggtat tctctcggct tccttgaaga aaccgatttg ggaagtaaaa tggaaatcga
    47341 attccagaca gattcctttg agatattgag caagcagctg attgaatatg gatcaggcat
    47401 tgaaatagtc caacctgatg aattaaaatg cataacccgt aaacacctgg cacaaattac
    47461 gaatcactgc ctaaacttga tttagagaaa gcgattggtc tgttatgtat tttttgtaag
    47521 gtttcatatc ccctgctgac atacagctgt cagtgtatta tgatattcta ctatcaaaaa
    47581 ggaggattga aaaatatgaa accaaagata attatgcaca cacaaattag ccttgatggc
    47641 cgcattaaag gctttgataa tccggaagtt tactaccagg ttgccggggg aattcattcg
    47701 gatgcggtgc tgtttgggtc caatactgtt tttactgcat ttgaaaaata tcctgctgaa
    47761 acagaggctg attttgagaa aatcataaca agcccggagg accccagacc aataggagtc
    47821 atacctgaca gcagaggtat cttgagaagt cttcattgct taagaaatct tggatatctg
    47881 aaggaaattg tcattctggt atcaactgcc actccgaagg aatatttgaa ttatttggag
    47941 gaaaggcatt acccatatat tgtgtcagga aatgatcatg tggactatga aaaagccttt
    48001 cagatcctgc atgagcaata tgggtgtaaa tacatgcgga cagacagtgg cggtggatta
    48061 accaacaaat tattagaaaa cggacttatt gatgaaatca gtcttgtgat atcaccatgt
    48121 tttgtaggta ataaagaaaa acaactattt gataaccttc tgttatctga aaaagttaat
    48181 ttggaattgc agggaacaga gaatgcagaa catggctgtc tgtcattgcg ctatgctgtg
    48241 aaaaataagg attagtgcag catactttaa aaagtgtctg ttgggacagt gtcctaaagg
    48301 aagcataagc tcatggctag cggcggtgtt aaagtaacgg cactcggccc caatatatag
    48361 ttgatatgcc cctaagcctt tgagggcaag gcggtcaacc gcgccttttc cggtccgcat
    48421 acagtcgttc aatgagggta tcaagctcgg caatgcggcg gtgcttctcg gtggttcgtt
    48481 tcttcgccgc cgttttcggc taattctaat tgatccgaac tgtaaggata agcaattatc
    48541 cggggctagt taagtatctt agagaggaag ataaagataa gtaaaccaat tttaaagttg
    48601 taccgaataa agccttcaag aggacaacat gcttttgaag gctttattgc ttacaattac
    48661 ttggattgta acgcaaaagc aggcaccaaa tcaatgaaaa atagcctatc caggcgactg
    48721 tttcagaaat atgggcttcc gccaagggga taccagtggg gtgcgacatc ttttttgccc
    48781 actcaaggca tgtagagtcc attgttctgt tgcgaaaaag ataaaaaatc aaatcagttt
    48841 tatagagatg taagttgttg atgataactt gcatcttttt catatgttaa gattggagtg
    48901 ataaggatga taaaaaatga tacatgtagt gaagatacca gttaaaaata aaacgaaaga
    48961 agtagtaaga attacagtat attgtagagt aagtaaaaat atagaagaac aacgttcagg
    49021 tttaaatagt caaattgcat attttaaaga actttctaac aaagtaatag aaatcgattt
    49081 agctgaagtg tatcacgatg ttggaagaag tgggttaata aagaatggaa gaacaagcta
    49141 taaaaaaatg attgtagatg gattataagg caaatttgat tacattatta caaaatcagt
    49201 tagtaggttt ataataaagc attgtagtaa aataaaaaaa tatgatatat ttagattagt
    49261 gataataaaa aaaaggagct aaaaatatga gttgtcatag tattgggcat ggattaaatt
    49321 cagtgtctaa aaaggtatta gagttgtatg atgaagggaa aattgaattt agtgttgcga
    49381 aagatttatt atacaccaca agaaatgctg tacattattg tgatggaaat acgtatgaag
    49441 cgattgcatg ttttgatgga tgtagatgtg ctagatgttt aaagaaaaca aatgagttat
    49501 atggtcttta tgatgcatta gatgagtgta gagagtatta tgatattttt agcaataaag
    49561 aagatggagt attatctggt gatctttgta aggattgttt tgatgaaatt tgtgaaaaac
    49621 accattcgat tatcatagaa gacgaagttg tatattaaaa aagttttact cgataatggg
    49681 taaatcttca acttttagcg gaattattag cagatagtaa taatatacct atgatatttg
    49741 tgaagtttaa tcttatattt tcaataaggg attactatac acattgctta tctcttttaa
    49801 tctttgattc acgttgagag tgttgtcttg atgtcaaggg ttcagaagta acatgtgaaa
    49861 aaggcttgaa aataggtcat tttaaaaata gattgtaatt tttaagtaca ttgaaatcac
    49921 gaaaatgctt gtaaatcagg gcatggaaac atatcaatac ggacagtgga gttgacagag
    49981 tagtaaccaa aattgaaggt gtgaactggt cttttagcga taaaatgttt gtctacttta
    50041 taaatgattt agagatgtat agtaagtggg aatattcagg tgaaagtgag ttgcttatgt
    50101 tggaatataa agagggcata ctatcttttg ataatataat gcaattctat ttagataaaa
    50161 tgatgcggga taaggttatt gattcaattc cttcattttt tcagcagtta cttagaatct
    50221 gtaaaaagtt taaagcatta aaagacatta gtaacgcatt tggaagggat aaattaatcc
    50281 aagtaactaa agaaaatatt ttaataatat tccatcaagt ctggcaaagg tatttataca
    50341 gggaaaatat ttctgtattc aaaactatgg aaaatgagct gtatacaatt ttcaaaggaa
    50401 tgaaatggaa cagttttatg aataaaataa aagtattcgt tcagaagccg gaagtaaaat
    50461 atatcaatct gtaacctttg caatggtgga agcatattgg aataaggata aaagtattat
    50521 agataagcag ggttgagagg aagagtctga gtatggacca gattaatagt tgaactatct
    50581 aaacataaat tggcagattt cggaatagaa tttactattg taaatcttta aaatatgcgt
    50641 cagttttatc ttgcttttcc aaaaactacg tattgtgtcg cgaattgagt tggacacatt
    50701 atcgcttgcc tatgcgagtg gagaaacccc gtgaatttta acgaataaat ttactccacc
    50761 attatgtaat gaaaatactt ttgtcatggt gtataaggcc tttattttac tgtatgtgga
    50821 gtcatagcat tgctatgtag agttgaaaag cctgataaac aaaggctttc ttttatttat
    50881 gtctactcaa aaatactgct ttcatttgta ttttaataaa aaattatgtt atgctcgata
    50941 tggaataaaa aacacattta aaatggaata ggagaatgtc aagatgaaga ttaatataag
    51001 taccattata gaggcgattg aaatggcaga tgataatttt acattttttt tatctgataa
    51061 aaataatatt tcttttaatt ttttcatttt actgcaccac ctttgtttga actttcaaat
    51121 caatcgcctc tgtataatgt ttccacattt cagcataacg tccatttttc tgtattaaat
    51181 cattatgttt tccactttca attaagcgac cattttccat aacaataatt ttatttgcat
    51241 tacgaattgt agaaagacgg tgtgcaatca taatgacagt tttgtcttgc ataagtttct
    51301 caaaagcctt ttgtatcaaa tattcatttt cagggtcgct aaatgcagtt gcttcatcta
    51361 atacaatgat aggggcgtct ttaataatag ctcttgcgat agcaattctc tgtcgttctc
    51421 cacctgaaag atgtatacct tgtgttccga ctactgtatc atatccgttt ggtaatttag
    51481 aaataaaatc atgacactgt gccgctttag aagctgatat gacttgctct tttgttgcgt
    51541 ttggatttcc catgcgaata ttatcgaaaa tactttgctt aaaaagaaat atatcttgaa
    51601 acacaaagct aatatgtttc attaagtcat tagttccaac ttcacgaaca tcaacatttc
    51661 ctattttaat gcttccagag gttacgtccc aaaaacgaga aatcaaatta gcaatcgtac
    51721 tttttccacc accagataag ccgacgatcg ctgttatttc cccttgcttt gcttcaaaag
    51781 aaacattttt tattgccagt tcattctctt ttccagtata agaaaaacta acattatcga
    51841 atgtaacatt gtcattatca aaagtctttg atatttgtgt atcttttaag actggaatat
    51901 taaatatttc gtccattctt gcaacatttc cattgatttg cataaacgat tctgaaacat
    51961 acataatttt gttaagtata cccgctactg ctggaacaaa gagcaaatag aagatgaaag
    52021 tcatcagaaa ttctttctgg tttactgcat tagtaccaat taaaatacct acgggtataa
    52081 gcacaagata aatattgtta attatcgttg taaatgcagg catacaattt tgccaaccta
    52141 atgaaaattt caatacccat tctgtatatt gagagattgc atgttttaac tgttcaaatg
    52201 aattagctgt ctgattaaaa gccttaacga ctggcatacc tcgtacatat tcaacagacg
    52261 cattattcat atcttcaaga gcaatttgat atttccccat attttctttc attgccccac
    52321 ttccataacc cataaactga acaataaaag ctaaaataat accaacaaga gaagcaatgc
    52381 cgaatctcca atcaatagca aataataaaa taaccataac aatcggagca gttacggaag
    52441 ccacaaaatc aggaaattga tgtgcaatga aaccctcaac actttctata ttttcgtcca
    52501 tgatttttct taaccgtcca cttccaatcg tcaaatgata acctaaaggt attttggtaa
    52561 tatgttctgc aaatttaacc tttaattcat acaatgttcc aaaagccgca agatgagaac
    52621 aaaatatcgc caaaaaatac aacaaaatat ttgcgataat tccacccaga gccaaccagc
    52681 cataccctat tacttcattg acatctaagc tattcaaatt tggataaact tgaagaatag
    52741 aacgaatgat gaagtaaact gcaatataag gaataaatga agcaatcgac gctaaggaag
    52801 aaagaatagc ggatataaaa atcagtcctt tcttatttga agccagttcc atacatcgtg
    52861 ccaagccagt tttaggcttt acctgttttg gcgttttctt tgccataata aatcctccta
    52921 actaaaaaat gatgtagtta gctcttgcta acatacatca ttttactttt tatatttatt
    52981 tgcttctact ccatagctat atatctatcc aaaaaatagc ccaaaagtgt taattttctg
    53041 cctttcgata atctttaggt aaaataccat ataccgattg aaatgcaata gaaaatttac
    53101 ttgcattact atatccaaga cttaacgcaa tatcatttat tttacgcttt gaatttctta
    53161 attcattaga cgctatattc atcttgtatt tttttatgta agaataagga gtatctccat
    53221 atacttgtgc aaagacttta tacagtaacg acaagttaat tcctttttca taagctaatt
    53281 gttccagaga tactttttct tctaaatgtt ctgtcatata tttgcaaaca tcttttgtta
    53341 tttgtatata ttttttgttg aaatatcgaa attcagtttc ttcattgccc gacagtttgt
    53401 tgatgaaata taaaaattcg attgctttaa cacgaaaata ggtaatactt tccttatctt
    53461 tagcattata aaattcttca aaaagatgtc ctaactcaaa gtctgcatga cttaaatatc
    53521 catttttatt taactttaat ctttcactta ttttgtccat atctaagcaa aaatcattta
    53581 gaattttttg tgtatctgca ctaagggcgt gtttatctat gactaagcta aatgcgtaac
    53641 atttttttag gggaaaggaa aaagatatag gcaaatgttt agtccccata atactgaaat
    53701 atccttctga caaataaaac atctgatgat tagaaaattc acattcataa cgccccgctt
    53761 gacaatggac aatagaaatt atatcaggat taaatttttg tgagggcata atttcatctg
    53821 tataaaaatc aagaaaacaa agtgtgatac cgtcataaag attataactt gtaataatac
    53881 cttttccttt acagccataa tctataataa cacaatcatt atcactatcg actaattgtg
    53941 ctttatctcc ataccaagat ttattaaatc tattatccat accaatcatc tctttttgtt
    54001 aatctattct aattttaata ttaacatata tctgaaacgt gagcaacgtt ttctgctttt
    54061 agggtaaagg gggctatctt tttttgataa ccccttaata cttatcctat aatcttccag
    54121 ttgctatcct tatgtagcac aagctcatat tgcgatacct gcgttgcctt tgtctgatta
    54181 tcaaggaatt tcacagcaac cttgactttc acattctccc cgtcctttgt aaagataggg
    54241 tttatcagtt cagaataaag gtaatctctg ccgataggtt caagtacatt accagataca
    54301 taataggcaa gttctttttc tgtggctgtt gggtacagct taaagaatgt ttccagaaat
    54361 gcggtagcgt cgtttacagt atcagcgtct acacttgcgt ctgcttctgg tgtcttaggc
    54421 tcatagtctg atttttcgat tgctggtgca agggtagggt tctgaacgat taccatatcc
    54481 ccgtcagcgt ctatatggac ttttacggta taggttgctt tcacattgct tgtcttttct
    54541 ccctctttta tctgctgatc tacttcgtag gtagcagaaa aagtgttcgt tcccgattgt
    54601 tcgatactcc atacaatcac atttgtagct gtggagctgg tcggtatatc cgttctgatt
    54661 gtatcaacat tcaagtcctg caattccttt gtcagataac cgctgattgc ctgcgtcctt
    54721 gcttcgatag cttctttgct gttattccat gtgtagtagg acttcgcaaa attcttcacg
    54781 aaattttcta tcccgttggt gtcctgcaag caaagttcaa tgatttcttt ttcatgggtc
    54841 gtgtgctggt cgatagcagt aaaattctta tacactccaa agctcacgct tgcgataagc
    54901 accacccaca acgcaatcac ggttttctta tgtgtgccta ccttaacagt acgcaccttt
    54961 ttttcttttg gttctttgat agtttctgtc tgtttcttat tcttcttaaa catatttttc
    55021 aagtcctttc tattgtttta ctcgtcctgc accgattaag tgctgttgcc agtaactatt
    55081 acttaggtct gcatatccta tcgggtcgcc cgcatggtac atctggttat ttcctacata
    55141 aatgccgacg tgggttacat acgaaccagc gttataggtg gaatggaaaa ataccaagtc
    55201 cccagccttt gcctgcgaaa gcggaagatg ttgggtagcg tcatattgtg cttgtgctgt
    55261 tctcggtaag gagataccag cttttccata acaccattgc atcagtcccg agcagtcaaa
    55321 ggaagtgttg ggattgctac cgccatacac atacttccag ccttgatatt tcaacgcttc
    55381 attcattacc ttttgtgcca gctctcccga tacctgcgga acagttaaat actgattgac
    55441 taattccaca tagaacatat ttccatagcc ataccgccag cccccgttct ttgcaacggc
    55501 tatcgggttg gtgtaggtta ctttctttcc acccgatttc tcacgggcga agctctctgc
    55561 aagattaaag gtatatttct ttccttttcc tgccacatat cccacataac caccgccata
    55621 attataggac tgtatcgcta cattcaagtc gtcgatacct tgattttggc aggaagaaag
    55681 cagggacgca aaatatttac acccctgctt gattgaactt tcggtatcta aagagttggg
    55741 tggtagtccc aaactttccg aactctgcat aacatcttct gccgtaccgc cactttctac
    55801 ttgaataata gcaagtagca cattgacata ctcggagata ccgttttctc tggcgtattt
    55861 ttccaccata ggctgatgtt tcaaaacttc tgcggataaa ttcataaccg taatgccaga
    55921 agaaaagttg ctgttttcgt cgtcgctgtc cgcactaatg aggacaccaa agaacagcac
    55981 cagagaaaag aggataggaa acagactgcc aataagagcg atatgtttca gtttcatttt
    56041 ttcttctgtc ctttcttcat tacaaggtta cggttctttt cggtatgttc cgttgtacgc
    56101 tttgattgtt caaaggtctg tgcctttgtg gtacgctctg ctttgtaatt ctggtgtgtt
    56161 tcctgcgata ccactttttc tacattctgc ctatgtgctg gctgtatagg ctgggacgct
    56221 tttctatcag aagcaccaga agataacgga cgctctttga taacacttgt cttgactggc
    56281 tcacttatct ttgaagtggt cgctgtggca gggcgtttga cttcctgcat tttttccaca
    56341 ctcggctttg gaatggtcga agctgtggct ggtcgctcat ggggacgggt agctcccgtt
    56401 gtcgctgatc cgtcagcctt tcgctgtgcc tgccttgctt cttgtgcttt ttgaagctcc
    56461 atacgcttgt cagcgatatt ctgcctgcgt tgctcctgct tttccaatcg tcccgtctgt
    56521 ctggactgct gttcctgcac catgccacgc ttgaaatctg atacgctgga ctttgccttt
    56581 tcctttgcgg aatataccgc ataagcggtc tgtgtcggca tatccttgat gttttctttg
    56641 acagcgtttg ccttgtcttt cactttattt ttcgtatcta agacagcacc cacctttgag
    56701 cctgctcgct gtcccatgct ggaagtggta ttgccccgat tttctttaga agctgtattt
    56761 tttctttccg ctcgtttgcc agcaacggca cttccagcca ccgcaccagc cacaccaccc
    56821 gaaataccgc cagcacttac tgcccttgca atacggtgtt ccatacgcct agctctatgt
    56881 cgcataaaca gatacggtct gcggaatatc ctgcgtccca tattttgact gtcgccagcg
    56941 ttcaaagaga acatattcat taagtcgcct aacttgataa agatacctgc gaaacacact
    57001 atctgtaaga acgccaccat aaaaaacggg taatctttgg agatgttata aaacatactg
    57061 gaaatactga acgccaccgt tacaatgagc gttattcctg cccgtgtcat tatggtatta
    57121 aacaccctca cgattgcctg ctttgccaga ttttcttgac taggtatcat ggaaagaaga
    57181 aaactgatag gcaaaaacat tgcaaagata ataaaaagta tctggcttaa catcattatc
    57241 cccatcagta agaatacaaa gattgtgata cctatattaa aaatgaatag gaagaacacc
    57301 atacccaagc ggtttaccac ctgcggtatc gtcagattgt tgttgtcgtt atcctcgatt
    57361 tctgttttca cgacttcctc tctggtcttt ccgtcctcgt cctctgggct tgccgataca
    57421 agagcttcta cacggtctgc cccgatttct tctgcgttgc tgttcccgaa ttgtaagagt
    57481 aaccacggct gttccacttg aatagaaaat agactgtccc gtatcaagtc tacgctgtcc
    57541 ttgccctcgc tgtcagagtt tgggagcatg atttttgttc ccaagtcaag tgaagcggta
    57601 ctgatgtctg atgaaaactc atttatcttc ttgatgtagt cgggagcata ggcaataaac
    57661 gaagcggaca gcacgaacac caccacaaag ttgataacgg catgaagtgc tttactggtt
    57721 tcccgtttga taagtcccgt atatgcaaca taaagtccca ccactaagat aatgagaagc
    57781 aggaaaccaa catagaagcc agagctggaa aaaccgtttg ccgtaacacc tgcaagggtc
    57841 tgtatgcttt ttccgatact gtctgccata tcgttaataa aatcaagttt gtaggcttcc
    57901 tgcaccacat agcccgtagc attgcttaaa tataggctta tcgtccagac aaagttggta
    57961 atgcagtaaa gcccgtactg caccgatttt ccgataccgt ccagccagtt ccacggaagc
    58021 cacgaccagc tattatccac ataaaaatca agctggtagt tggaaagggg atattttgag
    58081 taaagatttt ctgcgtttat ggtatcgtcc acaagccccg tcgcatgagc caccgtcccc
    58141 aaaagtgaaa gcaggataag ggagagtgcc accacgaaca gagccatttt aagaaagtgg
    58201 aaaatcttct tttttgtgaa cgcacctttt atcctttctt tcatcactcc acctcatttc
    58261 tctgtacggg cggtcttgta tcaaaggcgt gtagcagttc ttcaaaaacg gggtgtatct
    58321 gcaccacacc gacacgcccg tataaatcct gtaataaaca ttgtccgttc tccaaatcac
    58381 gcaagcgttt ctggttattt tcgtcgtcct tgtcaatgcc gaaaaattct aaggtctgct
    58441 ttatctcgtt gatgtcagta gaacgaaagg caaacttcaa gccgatattg tttttcagac
    58501 tttcctttgc cacgtcccca gaagattgtg taacgaaata aacgcctgcc tgcatagctc
    58561 gtccagcacg aaccagcttg tttgataagg tttcgccttg tgccacattt aagaacgccc
    58621 acgcttcgtc aaggtctaca atcttaaaaa tacttctgtc agaatggata aaatcaaggg
    58681 caaaggtact aatcacaatc agcatagaca ccgacaataa ttcaatggtc gtgtattcct
    58741 caaaagttgt gtccttatct ggcaacacaa ggtcagctac ttgaatgata ttgagctgat
    58801 tatccagact gatagcattt tccaccgtac cgtctgaaaa cagcaggtgt gcaaagtcgt
    58861 agtccgtgaa gctgtcgata tggtctgcga tatttcttga tactggcgta tcttcacggc
    58921 gtaactcgtc tatcacatgg agcaagcccc gactgtcgct ctgggtaaca gaacgtaccg
    58981 cttttcgtaa cacgggaaat ttttcgccgt ccctagagga aatacccgta aggaatgtta
    59041 agatgtcgat tgccagactt tcagcgtcct taacattctt cataatcacg aatgggtcaa
    59101 gaagtcctgc attgtccttg tcgcttgtta ggtttacgat attgatttca tgggcgattt
    59161 ctgggagcgt ttctttccag ttgccacgct cacttttagg gtctaacaga agtgcttgac
    59221 cgccaaacag caccgaataa tacaccagaa gattgttaca gaacgatttc ccaccgccaa
    59281 gcgaaccgac aaaagcagac gctaaagcgt tggtaactgt accttttaca ccttgactgg
    59341 caagggacgg ttgcaggtac acatttcttc ccgtatcaac agaatagccc atatagatac
    59401 ccgtagtttc tcctaactgc tgggtagcac caaaaccaag ccctgctaga aaatctgatt
    59461 ttacatactg cacataatca ttgatatatc gcttgctggc aggaagaaat tctgaatgaa
    59521 gccccagcat atccccagca ggacgcacca gttttacatt gaggtcgtcg taaaagtcct
    59581 tgacttcatc acaacggcgt ttcagctcgt caagatcggg tgcagacacc cgtatgacgt
    59641 agcttaactt atacatactt tctttgctct ggtctaagtc cgtttccagc tcgtccacgc
    59701 tatctaatgc gtccaccaca tttgagctgg tttcacttcc tgcttgataa gcgtgattgt
    59761 caaggtcttt caattccttt ttcttgttgc ggactgtcgt taatgctttc cgattttcca
    59821 cgatttctac attcatagaa gtatcaacgg ggaatgtgaa ttgctgttgc tggaaataga
    59881 agatttcact ggacggaaaa tccagctcgc ccacaatcgc attgacggta aagtaggaca
    59941 catagctttc cttgtcctca tgttccaatc gtaaatacct ttggctttcc tcaatcacac
    60001 atcttgtcgg acgaataagg tcgtagtatt ttatctgcgt ttctctcctc aatttcttct
    60061 ttggtaactg atactcataa tcttcataag cgacaccgtc cctaccgtaa agatgttcta
    60121 tgagataccc gaagtcgttt gtttccaagc gtcgcacctt gaaacgacgg gatattttgt
    60181 tttccagtaa cttttccatt ttcatgtagc ggttgatttc atcatttggc atggaaacaa
    60241 agtcattcat cagcgtgtgg ttcacttcat ggagaaattc cgtgaacgtc agccacgccg
    60301 attttttgat gttcttcaga ttgagctgtt cttccgtaac catgagctta aagccaagaa
    60361 aaaagcggta gtccacttga ttatccccaa tcatagatac taacgcttcg gtctgttcgt
    60421 ctatcttctg ataggcaact tcctttaatt ttccagttac cagctttttt gactgctcct
    60481 gcatacttcg gattgagctt tctgtggcaa tctgcaacgc atgaatttta ccctcacggg
    60541 actgtgcaat gagctgtcga aagctgtcat gcacgataaa tttctgctct gcggataaga
    60601 aagaatagtt gtacggtatc agctcataat aggcaaacac ctcattgtcc ttgttccaga
    60661 caaggttatt gtcaatatat tttatcggga acatagttca cactccttac tgccgtgatt
    60721 gtttcattga gtatctgctt atgcagtttt acggcttttc ctgcataagt gatttttggt
    60781 cgcagggcat aggttatctg tgatttcaaa aagctgtacg gcttctttcc gtcaaaagtt
    60841 ttctgcgaca taaaccaagt gagagcaacg ggaataccga agtatttgag aaatgctccc
    60901 tcaatcatgg aaagtggggg aatatcccca aacagaatga tgataaattc tgtaatcaca
    60961 aaccatgtaa tctgcgtaaa ggtaacggga aagggcaagt taaagtcatt aattgcatac
    61021 aagacttttt ccacgttcca gatacccgta taagatttaa tctttttcaa gttctttcag
    61081 ctcctttcaa aatagaaaag gacagccatg tttcagactg tcccttaaaa gagaaatacg
    61141 ctgtcagtag caacaatgct tgtcgctgat cttccagcgt taatatggta tctcgcacat
    61201 acctcggctt gtttcaatga agcaaccgcc catatccaaa tctcgcccgt aggcttcata
    61261 gtcaatgtag ttctgtaagc tgggtggaat gtcgccaagt gcctgcaatt cgtctatgta
    61321 gtagtaggca acgtctgtca tggtttcaca gtctggataa taataaatat cgtccttgtg
    61381 ttccacgact tcttccagcg tcccgtagtg gctgataaat tcgtccagac actctacgat
    61441 atagtcggga agttcctcta tcatttcata catagagttc agttcttcaa tggaaacata
    61501 ctcgccaatc gcaatgggaa agttatcggt atcatggatt gcgtattcct catactgttc
    61561 attcaagccg attttttctt tcacatcttc ctcgtcaatg gggaacgtga accacgcacc
    61621 gactaaatag ccctcgttgt atttgccaag attagcaata taaaccgcca tatcatcaat
    61681 cataagcacc acctcatttc ctactctggc agttcaaaga taccgtgttc cgttactaaa
    61741 aatttcccgt gttcctgcaa gtgagaagcg taggcttcaa agtcaaagta atattcttga
    61801 cagtcctcgg ataaatgttt gaacgtcggg tcgttcatca gcttttgcct tgcaacatct
    61861 atcatgcttt tgcagtcggg ataaaccgta atcacgttcc tgcaaatata aagtgcttct
    61921 aaattctcaa acaccgtaag aagtgataca tattcttcct gcatatcgct tgaaagctgg
    61981 cggtacataa aatctaattc gttgagctga tacacgctgg tatgttcgtg aacttcatta
    62041 gcaaaagcca acaccttttc aataatgcgg taatccccac tttctgcacc gacacctaac
    62101 ttttcttcaa actcggcaac atctatcggc aggtcgaacc agtatgatat tgtttcttcg
    62161 ccagttgttc ctctcgtttc caccagcacc cttgtttcct gcattgttcc tcacgtcctt
    62221 tctgttgttt catcacatct tttaaggtct ggtacggcat accaaacaca tactttgaaa
    62281 aatcttctaa ctgtctttct tcatagtcgg caaggttcag ccgtttcatt tcctgccaca
    62341 ccttacgctt gtaagagggc tggtcggaaa tatattcaca gccaaccttt acctgcatat
    62401 ccttaaaaat atcgctcatt tcatcactcc aatctgaaat ttaggtaaga aaaaagcagt
    62461 caatcctaag actaactgct ttgtgtgtat ggatatgaaa ttgtaaacta gattatctgt
    62521 tatagattta cagtcataat atattcttcg ctattttcat caacaacaag aaaacctgct
    62581 ttcttataca tctttactgc ataattattt ttttgaacag ataaggaaag ttttgaatat
    62641 ccagaagttt tttccaccaa caataactgt tgcaataatg aagttccaat cccttgtcct
    62701 ctatactttt gaaaaacaga catagcaagg gacggtgtat cattgtcaat gtgtccgtaa
    62761 tcgttcatta ttcgtaccca aatagcacca acaacatttc cttgaacttc cgcaactaaa
    62821 gccctatcat cttttcgctt tccgaattca aaaacatatt cttgcaattc tgggcagtta
    62881 atgattgatt taggtggtgg ctcaacaccg tctggaatat aaattgcatt atacaaaaag
    62941 tcattgagta aatcatattc ttcctttttt atttctcgta taatataatc catagcttaa
    63001 ctcctaatct attttatctt ttttcacacc ccgattatat cattcgcata tcagtaccac
    63061 aataaaattt tatgcaccaa taatcttatt gaacagctct aacagtacat ctttcacacc
    63121 gccagcattg aataccaaac cgacagcaat caaggcaact accaagaagc caataagttt
    63181 tgaaaactca cgtttaaacc ctaagtagat accgataacc acaatcgcca taagcactaa
    63241 gctctgtgcg tttgataaaa accattgata caaattttgt ccgaaattca tttaattgtc
    63301 ctcgctttct tctaattgtt tcatttcata gtcagcttct ttgccgatat tcaaaataca
    63361 catcaagact acaccgatac ccattcccat agataccagc aggaagtctt ttaataatac
    63421 ccacattttt atcactccta actttctact aaatcttttg caggggtcgt ctgctgtttg
    63481 attatcattt catgcttttc tgtgagcttt gcctgctgtt cgattgtttc catgtagtct
    63541 gtaccgtttc ccttatcaat ctttttcagc attttcaagg ttggtgctac ctgcctttgt
    63601 acccaccgca atgtacggtc taaggtataa ggctctggct ttgtcgtcag cttcaagctc
    63661 tgtctgttat cgccgataaa ccacgcccag cggtcattga gtttccagtc attttttcgc
    63721 ttgtctggtt cttcatcaac aaaccgcaca tactggttga tgatagaaaa ggcggtctgc
    63781 tctgcgtcat aataggtcag caaatctcgt actgcataat aggctcgttc attccgaagc
    63841 cgtatctcaa aacggttgat aatgtcggct tcttccagag gtgtccccag cttgacgtac
    63901 tgctcatagt ccttttcata gatacagaaa tacacatctg atttcagcga accaagataa
    63961 agggtacgtc ccatatattc tctgtcgtcc tctctgtgct tgataagctc gcccgactgg
    64021 taaaacttat agcttctgga ctttccgata tattcccgtt tcctgcattt ttccgcaagc
    64081 tctggaatat ccaaaatgcc cgtatggtcg ttgatagcaa ggtcgatacg cttcatcacg
    64141 ccaccgtcta cgagtgcgtc catgagaaag tcataccagc ttctttgctg tgccagcagg
    64201 taactttcaa actgcctgca cccacgcccc tttaactcta aaaggacacc tttttcttcg
    64261 tcagccgacg tatagataaa gatgtcccct aaagaataat gctccgtata actgtaacgc
    64321 ccgtaatctt catggagcat atagttgata ttcagtttta atatgtcttt gatgatgtgc
    64381 tgtatatcca gcgtgggaaa acggattttc acataatcaa acagcatggt aagcggtgct
    64441 tctggattga accttgccag ttctttatgc agagtttcca gaagttcttt tgacggcttc
    64501 atttttccac tttctatctt gttgagatat tcccttgtga taccagaagc caacgccagc
    64561 ctgccttgtg agataccata agcaatccgt ttctcccgta attcttttat ccattgttct
    64621 tcattcagaa ccataccccc aatctgtaaa gtgtgaagtt ttttaaggcg acttcacagc
    64681 cgatttttac taggaaacca tgtcagaagc cttatgtttc ctatgttttt tgtctattgt
    64741 ttatttgcaa acgtacccct ctgttagata ccgaggggtt catcagcaga gcagggacaa
    64801 gccctgctct gcaaaacggc ttccacggtc gtatttgctc cgccgaccgt tcctgccgtt
    64861 gtgcaggcag aacttatcct acctgttcat accaatgtaa accatgatga atgaaacatc
    64921 agcggataaa cataaattta atgtttcttc tgatatttca cttttacgga tagggtctgt
    64981 ttccagaaaa gacttatcaa gcaattcaaa aacaaaatca atctggctgt tgcaagccga
    65041 ctgttttcta tttaagcgta tcaagaacaa atcgggcatg aagttttttt cgtgaattgc
    65101 attttcaaga atagtatcag cttttttctc aaactgatgt tttggattac atttaaaatc
    65161 gtgataacgt ttctgcacaa atccctcgca atcggctaga aaatctccat aattgataca
    65221 gatacatttt acgctcttag atttctcgtc tttatcttct gattgtatta ttttattgat
    65281 ttcttttatt tccatgagtt agttctcctt tccttgttgt tctggcataa cttgtctttc
    65341 ttgtgcaagc ctgccgatag tctgcaaaaa atcatgtcct ttcgggacta aaggcgtgta
    65401 aaattcactt atcacgcttg ttcccacatc acaataacca cgccccttga tacgcttctg
    65461 gaaaaactgc tttttcacgt ctgaaccaaa cagcataccg taacctaatt cactgatacg
    65521 cccaagtccc acacggaaat tgaagttatc tctgataccg tctgaaaaat actttgcgtc
    65581 tggacgctgg caggcaacga taaggaaata tcctgcttgt cgtcccaaca taacgatttt
    65641 ctttaactgg ctaagcaggc tcacgctttc tttcgtccca agcatttcaa aaaatgctac
    65701 atattcatca aagataagaa agcagggtgg aagtcccaga taggcgtagt tttcgccagt
    65761 cttatagttc gggtgtcgct tcatttcctc acttcgctgt accatgccct cataaaaggc
    65821 attgacgcaa tctatcattt cttctttggt gtgatacaca tttcccataa ctgtccctaa
    65881 gtctgcaagg tcagcgttct tcgggtctaa gatataaagg acagcgttgg tatgcagtaa
    65941 ggcttcaatg agcgtcagca ggaaataggt tttaccgcca cccgttccac cagcaatcag
    66001 agcgtgaggg agtgcgtcat attcccagac aagattgttc atcagtttca gactgccgtt
    66061 ttctgcccgt acttcatcaa tggtaatgcg gttcgctatc atatcataaa gcagggtata
    66121 ttcgatatag ccgtcatgca gggtcttgtc ggtcagctcg caatacaagc cactttccaa
    66181 tttatcctct aaccgtaaaa gctggtcttg atattttcct aatgtgattt cacagcggat
    66241 atgaagcagt cccttttcca tttgataata aatctttgga aaccagacga ttttttccct
    66301 tgatctgctt tgcaggtcag taaaaaaacc gctgtcttgt acggtatcgg cttcatacca
    66361 cttattttcc agtatcattc ttgccagctt ttgacggtgc aggagcttct tgaaactgtc
    66421 gtaacagaag cggtaataca gaaaagcgac caatacacaa gcaccagtcg ctatcagtat
    66481 ggttatgaag ttgtaagggg agagcgtcaa gtcgttttct aacaagctga aatgctccca
    66541 atcggtacac atgagctgtt tgatattcag tagcagaaga accgccacga acacaaacag
    66601 aagcgtccct atggaaaagt ggtagacaag gtgcttgtcg ctggctctga tacgatgtcc
    66661 tttattccaa atcttacgca taaatcattc gctcctttct gggtatgaaa aaagcagtca
    66721 atcgtataga ctaactgctt tgtaaatgtt gcaagatata atcataaatc tgcattttta
    66781 gttatattaa ggtcgcacat ataatgccaa ttacaccaat agccaaaaat aacagtccaa
    66841 cacctgctga ttttttacgt ttttctaatt cttttgagtt gctttcactc atatttacaa
    66901 tagggtattt tcttcttccg attagataca taagcaaacc acttgaatta ttcccactca
    66961 ttgtaaatac tccccaaaat ttagggtgct ttaatcctct ggctgttgcg tctataacag
    67021 tcatatgata aatctgaaac acaacacaaa acgctcctac aagtgcaact gctccacaaa
    67081 ttaccgctaa aactatgttc aaatccataa caaaatatcc tccttaaaat tttttgatta
    67141 tctggtaaag taatgctgat gaagtgataa ccataagaca aaatattcca actaagaaat
    67201 aacggttatc tggtataaac atatttaatg ttatcagcaa tgctacgaca atgatattta
    67261 caataattgc ccatatcatt ttttggttgc tttttacaac atttgtactt tcttctaaat
    67321 gttcaatcat tttttcatca ccctttagca atacgtcaag acttatagaa tataggttgc
    67381 tcaactctat tacactgata atgtctgggt aagatttttc attttcccag tttgaaattg
    67441 tctgccttga tacattgatt ttttctgcaa cattttcttg tgtcattcca gactgtactc
    67501 gtgcattttt aagtttctta cctatttcca tatttcgatt gctcctttcg gtgtcattgt
    67561 catatattaa ccctcaaatg tctatccaat atcttcgaca aagccttttt tccttgtcaa
    67621 aattgtttta catagcttaa atacggctct tttggctcat tatactgtaa tttcagagta
    67681 aaatctatga cctagattta tttttttgac tgtccttgcg gtgtatggtt ctgtggactg
    67741 cctgcgttct ggttgccttt attcttcaac acaatatcct ctgcctttac ataccagtcc
    67801 acatctgcac ccgtataagt ttttcgtgat actgtatcgg ctactggatt gacaagctcc
    67861 acgactgcat tgtacggaaa ttcccttaac ggtacttctg gcggtacaga cacggggata
    67921 attccaccat gcagactgca cttcaaatca tagatacgct ttttaagctg ggtactcggt
    67981 gtcccgtcct cattctgtaa gaacacatca cgcaccgctg taaattttaa ttctccaaat
    68041 gttttttctt tgtcaataac aaacccgttt gataatctca taaattcttc actcctttac
    68101 ttttcttcaa ctgctacaat atcatcagca actaatacat aatcggtatg tcccatatcc
    68161 ccgattgcgt aacctctgcc gtataacttc ggattgacaa gttttacttt ctgctcatac
    68221 ttgaacttct tttcgccagc ctgcacggga atttccacca caacattttc gcctttctgt
    68281 acgtcagaat aaaggttata gcttcgtctg gctaagaccc tacggttatt tttatctctt
    68341 tcaaagatag gctcgctttc gcctgcaaat tcaagagttc caaaagactg tgccatatct
    68401 ggcacgacat atttcatttc catattgttt tacctcgttt ctttctattt ttaataaatt
    68461 gattgtgatt tcttattctg gcggtttggg aagtaccagc aatcccacag atagtaaagg
    68521 gtaaaatcaa tgcttacgca cccttgacta tccgtgttct tgcaggttgt tggcagacaa
    68581 gccagaataa gcggaagtct gccgtttgac agcttcggcg gagagcgtga tttttctttt
    68641 ctcataccgt taccgcctta tgattttttc attttacggc gtttgtagaa gaagatacct
    68701 gccagtccag caccagaggt caaaagaagt gcaagcagtc cgtaaaggtt tgtgttatcg
    68761 cccgttttgg gactgtcgct cggtctgtta ggcttttctg gtgtcggtgg tgtttcgggt
    68821 ttctctggtt cttctggctt ttccttaaag gtaattgtct gtcccttatc ctcaatatcc
    68881 ttatgttcgg taactttctt cggttcgtct ggattgctca aatcgtacaa ttcttcaaaa
    68941 gttacaagct gtttgccgtc aagagaagta gcgtcaaagg taaaggcaac ttccactttc
    69001 atagtttcgc tgtcagcgat aaacgtataa tcactttcca cacgttttcc attgataaga
    69061 agctctgcat tttcttccct taacatctgc cagcccacaa gtttgtactg tgtaccgact
    69121 tccaagccct ctaaggttac ggtatcaatg aatgtaacgt cttttccagc ttcaagctct
    69181 ttgttgccgt ccttatccgt agcagtcgta tgtatcttga tgatacgttc tgtaattaaa
    69241 acggtctgcc cgtcgtcctc aatgtcttta tgttccgcaa ctttcacggg ttcgtctgga
    69301 ttgctgaaat catacaattc ttcaaaggta acaaggtttt tgccacctaa agcagacgca
    69361 ttgaatgtat aggaaatttc cactttcatt tcttcatcat cagcgacaaa agtataatcg
    69421 ttttctacac gtttcccgtc aatgataagc tctgtatttt cttcttttaa catctgccag
    69481 cctttgagct gatactttgt gccttttgta aggccgtcta atttgacagt atcaacgatt
    69541 gttacctctt ttcctgcaag gatagttttt tcgccgtctt tgctggttgc tgtggtatgg
    69601 atagagattt ctttttcgta ttcatcagtc agcgttccta aatcaaccac aaggttattt
    69661 cttgatacca cgatttcaaa aggtgggata agttcaaaac ctttgttact gtcgcaacgc
    69721 atttcttcaa tgatgtaggt atcataaggc aacgcaccct tgctgtcgtc tggttcagaa
    69781 gttccaaacc acacaccgtc ctcgctggtc tttcctgcgt ttgtattgtg cttatgtgaa
    69841 gcccagtcag cagaagtgga aaactgcccg ttatcatcag ttaccacaac atgattttcg
    69901 cccgtcgtct tgcttgtgat cctaaaggga acatcagcaa gacgcttgtg tgtgcctgca
    69961 ccgattttta caccctcaat atctccacgc ttaatctgat tatagataga atgggcttcg
    70021 tctgttaagt ccacgatttt tccattttct gtgattgtaa aatcaatcgg ttttgcaccg
    70081 tcagttaagt aaccgttggg agcttcactt tcaacgatac ggaattttcc ataaggtaaa
    70141 aggtcagcag aagtagaagt gataccctca atatctgtac gaattgtctt taccacttca
    70201 tttttcttat agagcttacc ctcaaccaat accgcatttt catttaagga aatgatgtca
    70261 aaagctgtat ctttcaaagt ggcacttcct tgtggctttg tatcgcccgt ttctaaatct
    70321 cgtttctgaa ttttgacacc gccacggata accttgtctg atacggaaaa ctggttactt
    70381 ccagataata cggcaaggtc gccgtcctcg gtaatctgtg ttacatataa gcccttaatc
    70441 tgttcggact tatcgccagc ctgcatatat gcaccgtcta acaagtagcc gtttggagct
    70501 tttgtttctt caacggttag cgttccaagt ggaagaaccg ccttgccgtc ctgcatatag
    70561 aagctgtcgc cagatacctt gtaagcgtcc gctaattttg taatataatg ggttgtcccg
    70621 tcgccgtctg tttcagcgat tgtctttgta acccatgtac gagtagcttc ggcagggaga
    70681 ttgtctttgt tatagaagcc tgcataatac ttccatgtaa attccgcacc tgctagagaa
    70741 gcgttcccct gcggattgtc tttctgtgtt tccatatcaa tcttgaaaag ttcaatcaaa
    70801 gtgtccgtta ctttcggcgt atcagataca ttcaaggttg ctgtcgttcc agcttcaacc
    70861 tttaaggaat atacagtttt atctacttta tatcctgctg gtgcggataa ttccttgata
    70921 tagactgtgc ctgcttttac ctctgcaaca tctgtgtttc cgttttcatc agtcgtaagg
    70981 gtggcaagct gtttcgtgca gtccttatca gcaaagacac cgtatgttgc accagcgatt
    71041 gagtaattcc cgttaccgtc tgtaatgctg gtattactgg aagccttttg aagtttcgca
    71101 tttccgacat tcagtttcgc ccagaattgt cccaattcct gcccctcgcc agagtagata
    71161 taaccgccac attcatagcg tcctttattt tctttgacaa aggctctagc accagagaaa
    71221 acttcgtcct gcgttgcctt tggaatttca tcataagaag ctcgcacgtt atcacattgc
    71281 cagccaagat gtacgctcaa tctctgccag actacaagct gtcttaaaag gtaagcgtga
    71341 tttttgctta ttccgctgtg gctgtctgtg tactgtttca catattcgat agataaggca
    71401 acgtcgctta tctggtcggc actcatacgg gtgcttgcgt cagctctggt cttgtagccg
    71461 ttcctaaaat ctgtgttaat gtcgatacag taagcgtcct cgccctcaac ggttaaatgt
    71521 ccctcattaa aggtagaacc aatcgaaccg tcattcatta ctttttcaac gataccgaca
    71581 cgctcttttg actccgtcca gtattgcttg ctttctgcat gaacgggtgt cgtcggtaaa
    71641 gcagtaacga cagttgcaag agctaagaag cccgtacaca atcgttttaa catctttttc
    71701 ataaatctaa tgctcctttc attttgggta ataaaatagc cgtccaataa gaacggctgg
    71761 aaatagaaaa ggaacgtcat gttaggcgtt ccatagtcta taggttattc aattttttct
    71821 tgtttcaata ctgatgtgtt gtaccatatc tttgcatatc taggaaaact tgcgtatcaa
    71881 ggctcattcg ttagtagtaa ataagtagta aattgatgtg tttgtttcct tgaaaatgct
    71941 gatagatact gtattttagc ggataatcag atttttattg tgtttttata ataaagaaaa
    72001 gcataatttc tcgatattta aataccttta taattttata aaagatgaag gaggagtaag
    72061 agggattatt aaaatatgtg actttaataa attaatggca ctgataggta attaaggagg
    72121 aaattaataa tgggaacaaa catatttaac aaagaatatg tatttttaaa tgttgatgct
    72181 aagtcaaagg ttgaagtttt aaaatttata tcaaaaaaag ctaaagaatt aaatttggca
    72241 gaagatgaaa gcttagtata tgaaggttta atgtctagag aagaacaatt tactacaaat
    72301 ttaggagaat ctatagcaat tcctcatact aaaaatgatg caattgaaaa tccagcagta
    72361 gtagtgttga agtttaatga agatgttgtt tggaatgaag gtgaggataa ggttaaatta
    72421 gcaataagct tacttatgcc aggaaaaagt aaagaaaata ttcatcttaa attgttatca
    72481 tctctttcta gaaaattaat aaataaagac tttaaagatt ctcttttaaa gagtgataat
    72541 gttgaagaaa tatctaactt aataaatgaa gctttaggtt tataattaaa cactaaggtt
    72601 ataaaataaa aaataattaa ctaaaaatag gaggaattta aaatgaataa aaaattagta
    72661 gcattatgtg cttgcccaat gggattagct cacactttca tggcagcaga agcaatagag
    72721 caagcagcaa aggctttagg ttatgaagca aaagttgaaa ctcaaggtgc agatggtgta
    72781 caaaatgaat taacaagaga tgatatatta ggagcaacta tgataataca tgcagtagca
    72841 ataactccag aaggtatgga aagatttgat gggtgtgaag tttacgaggt tgagttacaa
    72901 gaagctataa aaaatgcaga gggtgtcata aaagaaatag aagaagattt aggaatataa
    72961 taaatttatt gtggaggaaa tagaatggca attaagaaaa aagttataaa cagttcaggt
    73021 gcttctacaa caggaggaaa taatgtagga aaatctactc catctagtcc aactcaatca
    73081 aagggaaatg gaaaatggaa agaaataagt aaacatataa tgacaggtat atcatatatg
    73141 ataccagttt tagtaatggg tggacttata ggagctttat ctcaactaat accatatgct
    73201 atattaggac ttgacccatc tgtaggtata gttgatgcta tgaactcagg agaatttaca
    73261 gggttcaagc ttagtctttt aaatatagca caattaatgt caaatttcgg atttactttg
    73321 tttggatttg caataccact atttgcagca ttttgtgcaa actctatagg tggaaaaaca
    73381 gccttaattg caggatttat aggtggatat atagctaata aacctgtagg tgtaccacaa
    73441 tttgttgatg gacaatggac tgaagttgtt ccagttgcat caggattttt aggcgcaata
    73501 ttaatagcat tcataatagg atattttgta aaatggttaa ataaatctat aaaagtttct
    73561 cataactggt tagcttttaa aacaacattt ttaataccac taatagcgtc attagcttgt
    73621 atggtattga tgatatttat aataactcca tttggtggac taattaatga aagtatgaaa
    73681 aacttcttaa cagcagcagg agcagcagga gaatatgtat atgcaacagc tttggcagca
    73741 gctacagcat ttgacttagg aggaccaata aataaagcag caggattcgt tgcacttggt
    73801 ttaactacag agaatgtact tccaataaca gcaagaacaa tagctatagt tgttcctcca
    73861 attggattag gattaacaac attattagat aaaaaactag taggaagaag agtatatgat
    73921 agacaattct atcaagcagg aaaaacttct atattcttat catttatggg tatatctgaa
    73981 ggagcaatac catttgcact tgaaagacca ggctttgtta tacctttaaa catagtagga
    74041 agtgtaatag gagctattac aggtataatt ctaggagcaa ttcaatggtt cccagagtca
    74101 gcagtatggg catggcctct agtagacaac ttatttggat atataatagg tatagcagtt
    74161 ggtgctatat ttatagcagt aggaaatata ttctatagaa ataaattaat aaaagatggt
    74221 aaacttgttg tagattatat cgactaatat ttaattttta ctatctataa ataaccttgg
    74281 ctggtaatat ggttttaatc aatattacca gccttaccta tatgattaat tagaggcggt
    74341 ggagataaga tatggataag atagaaaaag taagagagta ttttagagaa tatgatatag
    74401 atggatttct tatcaatagt cctacaaata agttttatgt tggaaattta tttagttctt
    74461 caggttatgt ttttataacg aaagaagcac aatatataat agtagatttt agatattttg
    74521 aagaaattaa aagaaaatcg agcttgttta atgtagtatt aatggacaaa actagaactc
    74581 attttgatat aattaatgat atttgtagag aacagaatat aaaggaaatt ggatttgagg
    74641 gaaatgaagt atcttttgat ttatatagaa gtatgagtaa taagttaagt gcaaccttaa
    74701 aatcagttga tttatctaca ttaagggaaa caaaaaatga agacgaaata aaatatataa
    74761 aaaaagcttg tgaaatagtt gatgctacat tttatcatat aatagacttt ataaaggttg
    74821 gtatgactga aaagcaagtt gaaaatgaaa ttgttagagt tataaaagat ttaggtggtc
    74881 aaaaagaatc tttcgataca atagttgcat ctgggcttag aggagcattg cctcatggaa
    74941 aagcaagtga aaaagttata gagtatggag attttgttac ttttgacttt ggtgctaagt
    75001 acaataatta ttgttcagat attactagaa ccatttgtat gggtactata aataaagagt
    75061 tagaagaaat atataatata gtaagaaaag ctaatgaaga gtgtataagg gttttaagac
    75121 caggaatgac tactggagag atagataaag ttgcaagaga tataattggt tcatatggat
    75181 atgccaataa ttttggtcat aatctgggtc atggtgtagg aattatggtt catgaatatc
    75241 ctgcattagc tcctgaatca aatgaagtat taaaagaagg aatgattgta actatagagc
    75301 ctggtatata tgttccaagt cttggaggcg taagaataga agatgatgta cttataacaa
    75361 aagatggatg tatgagattg actacatcta ctaaggattt aatagttgtc agttaaaaat
    75421 aaattaggta aatattttat aacaataaga aaagaagagg taaatttaaa tgtataattt
    75481 tgataataaa ccagatagag taagtgagaa gtgtagaaaa tgggatttaa atattataag
    75541 agataaattt ggagatatta gagaagattt tgtaccaatg tggattgctg atatggattt
    75601 taaaatacca acagaaatag aaaacaaatt tattgaagct gtaagaagag gtgtatttgg
    75661 atatacatac tgttatgatg aattttatga ttcagttatt gggtggcaaa aaaatatgca
    75721 tgaggtagat gtagaaaagg aatggattac attaacttat ggaactgtat cgacacttca
    75781 ttatgtagtg caagcttttt gtaaaaaagg cgatagcata atattaaaca caccagttta
    75841 tgaccctttt gaatcatcag caaaaaaaca gggtgtaaat gtaatttgta atacattaga
    75901 tgttgtaaat gatagatatt atataaattt tgataaatta gaagcacaaa ttaaggaaaa
    75961 taagcctaaa ttaatgatgt tttgtacacc acataatcca tctggaagga tatggacgat
    76021 tgaagaaatg acaaaagtag caactatatg taaagaaaat aatgttattt tggttgcaga
    76081 tgaagtacat gcagaacata ttcattatgg taaatttaat tcaatactta agattgaaaa
    76141 agagctttta gaaaatgtta ttctattgac atcaccaaat aaaggattta atcttggtgg
    76201 attaaagacc tcttattcaa tagttataaa taagaatata agagacaaat ttagaaataa
    76261 actaaagcaa aattctataa cttctccaaa tgtgtttgga ataatagggt tgataactgc
    76321 ttataatgaa tgtcatgagt ggttaaatgg tgtaaatgaa tatataaagt caaattatga
    76381 acttttagaa acttgggtaa ataaatatag taagataaaa ttgatgaaaa tggaatcatc
    76441 ttacttagct tggatggata taagtggatt aggcataagt gcaagtgagt ttacagatag
    76501 gttggctata gatacaggag tattattaga agatggaagt cattttgtac aagatggtga
    76561 taagtatgtt agaataaatt taggaactca aaaagaaaat gtaattgaag ctttaaatag
    76621 aatggatttg tttttaaaat ctttataaaa atttggttaa attatttatt gaaaatataa
    76681 aaaagtagct tattcaatta taaaaataaa tatatttaat ggtaggcatt tcttatgaaa
    76741 tgtctatttt tatatgatta ttgtaaagtt tcctttacaa taaaatagta atatgatata
    76801 ttatatgtgt aaaggaaact ttacaatgaa ggaggagata tttttgaaaa attgtgtaga
    76861 agctttgaga aagaaaaaag gtcttaatca agaggacttt gcaaaaattc ttaaggtttc
    76921 aaggcaaacg attagttcta ttgaaaatgg aaaatataat ccatctttag aacttgcatt
    76981 tcagatatct gatttttttg aaatgtcgat tgaagaaatc tttttatgga aggagatata
    77041 atttatggaa aaaaggaatt taagaatagg aatagtatat gtagttttag gagttacttt
    77101 cttgttttct tgtttaatga ctaaggataa gttaagttct ttgcttgttg gtttagcagc
    77161 aggatttgga tttaatggaa tttctataat ttatcgatat ttttactgga ataagcataa
    77221 ggaagaatat agagaaaagc tagaagaaga aaaaataaac cttcaggatg aaaggaatgt
    77281 aatgtataga gataaagcag gacgatatgc ttatattgtg tgtatgatta taattcctat
    77341 atctgctttt gttttcgctg tactaaacgc cttagatata tacaactcat tagtaatcat
    77401 tatatatcta tctgttttat ggattgtttt gtatgttgta ggagttattt actatcgaaa
    77461 gttaaaaaat aatgaatagt atttatataa atttaagcta ttaatgtggt atatacataa
    77521 gtacaatttg ttttagacta cttaagtata taccacattt tatataaatt ttaaatttgc
    77581 attagttatt taataactat ttaaattcat atgtattttg tatttataat aggtaaagtt
    77641 attatttaaa cttattattt atttaatttt tcaatagaaa aggctttatc tgtaagttta
    77701 aaattatctt ttataccctt agttaagtat actttcttat ccttagttat gaatatagca
    77761 tctacattat caattctatt aattaaatcc ataccttttt caagtccaag tccaaatgta
    77821 gaagtggata aggcatcaca attaatagat ttatcagaga ttattgtaac actacttaaa
    77881 ttgttttcaa aaggataccc tgtaaatgga tttaacatat gatgatatat ttttccgtct
    77941 ttttcgataa atctttcata aattccagaa gtaacaacag atttatttgt tgtttctatg
    78001 tttcctatag attcaccatt tttactagtt gggtcttgaa tacctatttt aaaaggttta
    78061 tcatttttac tgtcttctaa agtgaatata tttcctccta agtttactaa accttttttt
    78121 atatcctctg attttaaata ggatacaatt ttatcagcag catatccctt agctatggca
    78181 cctaaatcaa ttttcatatt ttctttgttt aattttatag atttattttt ttcatccagt
    78241 atgatgttct tataatcaat aagaggcaga agtttttgta tctcagaatc acttggaact
    78301 ttagctttat ccgttccaat cgcccataaa tttgataatg gaccaattgt tatatcaaaa
    78361 tatccatctg ataatttgga atattgtata gcttctttta cgacgaaaaa tgtatcatcg
    78421 gaaactttga caaatttctt accagcatta tcatttattt tagaaacatc acttcctggt
    78481 atatgagtgc tcattttgtt gtcaatatat cttaaaattg aatcacattc atttaagatt
    78541 ttatcacttt tggattcttt tacattaaat acagtaactt cgtttactgt accaaggtag
    78601 tagctagtct tactatattt agtattctgg cctgaactcc taaaaaatga aaataaaatt
    78661 aatgctaaaa tcaatatcac aaaaataaat gtgatttttt tcttattcat ggtatattcc
    78721 tcctatgaaa ttgtgttatt attttattat aacataattt cataggagga caaaaaatga
    78781 agaaaaaaga cattcttctt attttaggca ttttggttgt tattacagca tgttatggga
    78841 taataaatgt tataaattct aaaaatgctg gaaatattga gatttatgta gataataaat
    78901 tgtataaaac tgtttcaata aatgcaaaag aagaatttaa aatagagaat agaggggggt
    78961 ataacatagt aaagattcat gataaagggg ttgaaatagt agatgcttca tgtcctgata
    79021 aggtttgtgt acatactgga tttataaaca agccaagtca aagtatagtt tgtataccta
    79081 atagagttag cataaaaata aatacaaatg aaaagaatga taatcaagaa gatataattt
    79141 ctaaataaca taataaaaat aattgaaagg aattggtgat agttatggtt aacttaggaa
    79201 acgattggga tgaattattg aaagaagaat ttgaaaaaga ttactactta aatttaagaa
    79261 aatttcttat agaagagtat aaaacacgtc aaatttttcc aaatatgcat aatatatatg
    79321 aagctttaaa gcacacttca tacaaagaca caaaagtttt aatattagga caagaccctt
    79381 atcatggaga taatcaagct catggtttag ctttttcagt tcaaccacaa gtgaaaaccc
    79441 caccatctct attaaatatg tacaaagaat taaaagatga tttagggtgt tttataccta
    79501 acaatggata tttaatgcct tgggcagacc aaggagtgtt acttttaaat actgctctta
    79561 ctgttagagc gcatgaagct aattctcata agaacaaagg atgggaaatt ttcactgata
    79621 gagtaatatc tattttaagt gagcgtgaag acccagttat ttttgtatta tggggaagta
    79681 atgcacgtaa aaaagtggaa ttgattgata caagtaaaca ttatatttta gaagcacctc
    79741 atccaagccc attgtcagca agtaaaggtt tttttggatg taaacacttc tctaagataa
    79801 atgaaatttt gaaaaagcta ggaaaagaac ctattaattg gcagatagaa aacatataaa
    79861 agtaaaaggt aacaaaatga taacaaaaca caataaacaa tgacattgtt gtaactaata
    79921 gaaatatgct taaatagttg aaaaaactat atatgcatat ttatattttt ttgtcaagtt
    79981 gacaactctt gaaaaaatag ttacaattta gttacacaaa aaacacaaat aaaaaaagaa
    80041 acttacaaag cagaatttta tgaagcaaaa tatatagtgt aaaaaatctt agggaggaaa
    80101 ttttatatga attttaaaaa attgagtaat gttaaagtct cggtaatggc agttgtttta
    80161 tcagttggaa tattatcggg atactctgcg cttaataaac aagtaacatt agtagtaagg
    80221 ggagaagaaa gaactatatc aacattcagt tctaatgtag gagacctttt agaatctcag
    80281 aacattagct atgatgcaaa tgatatagta actttagata aaaatgcaaa gttatctaat
    80341 ggagataaaa tagaagtaat tgatgtaaag gaaaaaacag ttgtagaaac taaagacatt
    80401 ccatttgaag ttacagttgt tgaagatggc tctttattaa agggtgattc taaggttaaa
    80461 gaagaaggaa agtctggtaa aagtgaatta atatataaag aaacttatca caatggaaag
    80521 aaagtagaaa aagaatttgt gaaaaaggtt gttaaagctg agccagtaaa taaggttgta
    80581 agtaaaggga caaaggtaga aatgcaagta gcctcatcaa ggggagaaag ctcaagaaga
    80641 atggcttcat catcatctag tagcagtagt agtaacaatg gtaaaaatat gagagtggta
    80701 gcaactgcat atactggtca cagtataact gcaacaggaa caaaacctaa gtggggaaca
    80761 atcgctgtag accctaaggt tataccatat ggaactaaag tttatatacc tcaatttgat
    80821 atggtgttta ctgcagaaga ctgtggtgga gcgataaaag gaaataaaat tgatatctac
    80881 atgaatgatt caaaaacagt ttataactgg ggaagaaaaa ctatagatat acgtatatta
    80941 aaatagttaa ataatttata tttacactgg aaattatatt ttgattatat agagaagaaa
    81001 ttctttatag attcttaaaa tataattttc agttttttat tttatatata ataaaaaagg
    81061 taaattttaa ccatgtatag ataaaaccta tttaaattat aatttactat cagataaatc
    81121 tataaaaatt gttgcaaaga gtcaaaatat atgatattat agatttcgtt gagaaggatt
    81181 tcattatggg agtggatggg tgccggtgtg ccctctagtc ttcaaaacta gtatgagggg
    81241 ttaagagcct cttaggtggg ttcgattccc acgcattccc gccaatatgt aaaaggtatc
    81301 ttttaattaa aagatacctt tttaaattta ttttaagata gtttattttt aataatatat
    81361 aatattttgt attatataat gtaaattttc taatactatt atatatttag ataaaaatct
    81421 gggagtgtgg aaagatggaa aataatttta cgacgagaac tagttttcta gttggagatg
    81481 atggaataga aaaacttaat aattcaaaca taatagtatt tggagttgga ggagttggta
    81541 gttttactgt tgaagcttta gcaagagctg gagtaggtaa tattaccatt gtggattttg
    81601 acgatgtaga tataacaaat ataaatagac aaataccagc actacattca actgtaggaa
    81661 ggtataaagt tgatgttatg gaagaaagaa tattagatat aaatcctaat atcaatataa
    81721 aaaaaataag aagtctttac aatcaagata ctagtgatga aatactgact gaaagatatg
    81781 attatgttgt ggatgcgata gacatggtaa gttccaaaat acatctaatt gaaacttgtg
    81841 agaaaaaagg attaaaaata ataagttcta tgggtatggg aaataaatta gacccaacca
    81901 aaatagtcgt tacagatata cacaaaacaa gcacttgtcc tctagctaaa gttatgagga
    81961 aagaacttag ggatagaggt atcaaaaagt taaaagtagt atattctact gaacaaccaa
    82021 tagaacttaa gaagaaagta atgaatggta gaaaggtaac acctggtagt gtatcattcg
    82081 taccatctgt aggaggttta ataatcgcat ctgtaataat aaatgagcta ttaggacaat
    82141 aagttttaaa tattttaatt tataaatttt atatataaac ttgaaggcta gaagaattaa
    82201 tataaaatag ttttatatta attcttttag cctaattatt ttacattacc ttattttatg
    82261 tagttgtagt tttatttttt tgattatgta tctacttcat aattatattt tgtaaatata
    82321 atttctccat cactataaaa aacaatatct cctattctgt ctgttctata aattgataca
    82381 tggctttgtt ttagattatc aataacctct ttatgtggat gtccatattg attcttatat
    82441 ccacatgata ttgcagctat gtctggatta atttttttta taaattctaa agatgatgaa
    82501 gaattacttc catggtgacc tatttttata aaattaatat tgtttaattc aaaagaacgt
    82561 aaaatttctt tttcattttc ttcttctgca tcacccataa ataaaaaaga gttattgtta
    82621 aaagttaatt tgaaaactat agaatttaaa ttagattctt cttgtatata tgatggactt
    82681 aatacatata tatttatatt gttatctatg tttaaaacat catctttgta gagatactga
    82741 atagctaagt ttttatccgt acaagaattt attagatttt gataagattc actattagtt
    82801 gattgttcag gcatatatat ggagtttaca ttaaattttt ttataacatt atcaagactt
    82861 cctatatggt ctgaatctgg atgtgttgct attataatat caatagtttt tattcttttt
    82921 tgtctaagat aactattaat tatattttta ctatattcat cacctccatc aattaatata
    82981 ttcttatttg tgggcgtttg aactaaaata ctatcacctt gtccaacatc aatcatatgt
    83041 atagatagta gagatttttt gtcacagccg attaaaagtg atattataat aagtattgat
    83101 aaaaaaattt tatttctcaa taaaaaatca ctccattcat tacatgttta tataaattta
    83161 tgatgggtaa tataagatat atatggctta ttatatttta tattttaaac aatataaatg
    83221 aaattaatac tataataaaa ttggagtttt ttatatatac aaaataaaat ttttaaaatt
    83281 aagcaataaa aaggcaggag gattttatgt ttttcaaaga tattgaacta aattcaaaaa
    83341 aagagttaga cccatatttt gatttagtag attatgaagc ttgtgagtac tgttttagta
    83401 ctttatatat gtggcaacat gtttataaga caggatatta tataggtgaa gattttgccg
    83461 ttttagttgg ggaatatgag ggagatagct tctcaatatt accacttgct aagaaagata
    83521 aacttccaga agttgtagat tttgtccttg aatatttttc taaaaataat aaaaaaatat
    83581 acttaagagg tattactact gaagttgtag aatttttaaa agaaaaatat ccagatagat
    83641 ttgagtatat agaagaaaga gatttatttg actatattta tgatgcagaa agtttaagaa
    83701 ctctagctgg taaaaagaat caaaagaaga gaaaccatat aaactatttc ttaaaagagt
    83761 atgcaggtag atatgaatct aaattattag ataaagaaaa ctttgatgag tgtctagtat
    83821 taatgaagga atgggaaagt aataaggaag aaaataatga atttgatgaa agtatggatg
    83881 atgaattaat aggtatcaaa aagatattta accattatga catattaaaa gataaggtaa
    83941 aagtatttgg tgtttatgtg gatggaaaat tagaagcttt tagtatagga gaacttttaa
    84001 atccaaatat ggcattgatt catatagaaa aagctaatcc agatataaga ggtctgtatc
    84061 catttataaa tcaacagttt ttggtaagtg aatttaagga tgttgagttt gtaaatagag
    84121 aagaagattt aggtattgaa ggattaagaa aagctaaact ttcttatcat ccttgtagat
    84181 ttgttgaaaa gtacagtgtt agggaggctt agtagactat atggagatta ggtatgctaa
    84241 agaagaagat atagaaagta taaaagagat ttggagttat tgctttaatg atactgagag
    84301 ttttatgaaa tattatttta atgataaata taaatctgaa aatactgtag tagctttaga
    84361 tgaaggaaaa attatttcct ctcttcagct aaatcagtat aagttactat taaataacaa
    84421 ggtatacaat acatcatatg tagtaggcgt ttctacactt ccagaaggaa gaggaactgg
    84481 atatatgagt aaagtaatta aatttacttt aaacgaattg tataaaaaag gacaattagt
    84541 ttctatattg atgcctattg actataggct ttatagaaga tttggatatg agcattgtta
    84601 tgaccagatt gaatatacta ttaacacaga tgatttaaaa aattttaagt caagtggaaa
    84661 aatgataaag tctaatttat cacaaattga tgatttgata cgaatagata gagctttttt
    84721 aaatgaggtt aatggtaatg tgttaaaaga tgaacattat tataaaaact tatttaaaga
    84781 gattcaaagt gaagatggtt ttttgtacat tcatgaagga aatgaaaaag atggatatat
    84841 agtttatttt attaatgaag ataaaatgtt tgtcagagag ttattttata aaaatataga
    84901 tgcccttaaa tcaatgctta aatttatata caatcacaat actcaatgta agatagttac
    84961 tatatctact cctataatag ataagataag atttatatta gacaacccta aggatagtga
    85021 gataaaaata aaacctttta tgatgggaag aattataaat gtaaagaagt ttattgaaga
    85081 tgtagatatt gagaatgata ttaatagctc atttaattta ttaatagaag acaagtttat
    85141 aaatgaaaat aatggtttat ttaaaatttc tatacaaaat aagaaggtat ctgtagagca
    85201 attatataaa aaagatgaag agaagcctca agaagatttt gatgttaaat tagatataaa
    85261 taccttaaca cagttagcat tttcttatat agatgtaaat gaagctattt tcttaaatga
    85321 tataaaagat gtttcagaag aaacactaga aatacttaat tgtatttttt ctaaaaaaaa
    85381 taactatata aatgaatata tataaataga gtacgttaaa agattataaa aatcttttga
    85441 cgtatttttt tgtttatata ataatttacc ttgtttaaaa attttctatt tgaaaataat
    85501 ctaaataata tgcttttata tgggagtgat tataattcaa ataagaagac ctttattaat
    85561 tatattagtg tttgtgatag ctatatcatt tatcattaca aataatacaa aaaacaacga
    85621 agaaattaat gataagataa taactataca aggaattgtc aagggaaaaa ttgaaaagaa
    85681 aagatacaat cagtataagg taggagtttt tttaataaat gattatacaa aaaataaaaa
    85741 tttgaagatt ggtcagaaag ttaatattac aggaaaattt aaaagtttag ataaaatgaa
    85801 gtatgacgat tttgattatg gaaggtatat aaaaagcact ggatataaag gtatagtata
    85861 tataaataac tataaaatta ttgataaaaa taaattttat tctttaatag gagaaataaa
    85921 gttttatatt agcaagactt ataggtactt atataagaaa aactcggatt ttataaattc
    85981 tatactatta gcagaagttg aaaatttgag tgaagaacaa aaagaaattt ttaccagaac
    86041 aggaactagc catgtaatat ctatatcagg tcttcataca ggaatattat gtataattat
    86101 atcctttcta ttaagaggta taaataaatt gtataaatta ttaatactgt cgatttttat
    86161 aactttatat tgtataatgg taggtgcgtc tccatccata attaggtcta tagcatttgt
    86221 tatgattttt tatttatcaa tatttattga tagaaagaaa gatggaatat cggcattgtc
    86281 tctaattggg ataattttaa ttatgaataa cccctatgtt atatataatg taagttttca
    86341 attgtctttt ttagctacac tttctatatt aatattctat aataaaataa atagtattat
    86401 aaaattaagt atggtatcat tgacaatatc atcaaatata ttaactttac ctataattta
    86461 ttatacattt aaaggtatac cattactttc aattatagga aatttaatta tagtaccatt
    86521 tgtgggagta ataatttatt taagtattgc aagtttaatc gtatttaaag taagtgtagt
    86581 aatagctaaa attatatcct tttttaatag tacattgata gaaagcatat tttttttact
    86641 agaaaaaatc agcaatttaa gttttgcata cattaatata gaaaaaccta aattttatat
    86701 tgttatcatt tattacatag gagtgttttt ttacatattt tacatagaag gaaaagagat
    86761 aaaggagcaa gagaatgaat tacaaggata ttataaggaa tgtaaaagag aaaaattttg
    86821 aaaaaatgta tcttttttat ggaagagagt attatttaat tgagaatgca ataaaagcat
    86881 ttaaagatag tctaaacgag ggaatgcttg attttaattt agatataata gatggaaagg
    86941 aaatagtctt aaatcagctt ataagctcta tagaaacact tccatttatg gatgatagaa
    87001 aaatagtaat aataaaagac tttgaactat taaaaggaaa gaaaaagaat tttacagata
    87061 gtgatgagaa atacttaata gagcatttag ataatattcc agacactaca actatagttt
    87121 ttgttgtata tggtgatgtt gataaaagaa agtctctagt taagaaaata ggaagcaatg
    87181 gaatcgtttt tgattgtgac aagctttctg atatggattt atttaaatgg ataaaaaaat
    87241 cttttgcatt aaatgatgtt ataatagata actctcaaat aatgtacttt atcgaacaag
    87301 aggggtatag agataagagc agtgaaaaga cattatctga tttagaaaat gaaataaata
    87361 aaataagttc atttgttggt aaagggaata atgtaaccaa tgatgtaatt gataaattat
    87421 ctcaaaaaaa agttgagaat gatatattca aattaatcga ttacattgga gagcaaaatg
    87481 cttctaatgc aatgaaaata ttaaatgata tgatacaaga aggcgaatct gtattaggta
    87541 tattttctat gatagcaaga caatttaaaa taattatgca agtaagacag ttacaacttg
    87601 atggatattc aacaaaactt atagctgata aattaaaaat gcatcaattt gttgtaggaa
    87661 aagcattaaa gcaaactaaa aatttttctg atgatataat tgtggaaata ttaaactata
    87721 tactagaaag cgattataaa ataaagacag gccttataag agatacctta gcagttgaaa
    87781 tgttggttag tagatactgt aaaagggaag caatataaaa aatctatata ttaataaaaa
    87841 ataaatagca agatatgtta tagtttagag tagatgtaag ctaaattaag tttaagtata
    87901 tacaatcaac tataatatgt ctaactattt attttttatt gtataaattt acaaaataaa
    87961 aaacccctac ataggggtta ttatatataa gaaatataaa ctggtaatta agcgttcata
    88021 ccgtttaatt tttgagctaa tttagctact tttctagctg cagcattctt atgtatagtt
    88081 cctttagaag ctacttggta tattcttttt tgagcgtatt ggaacttagc aacagcatcc
    88141 tctctgtttc cagctgcaac agcatcttcg aatcttctta ttgcagtttt tatttgagat
    88201 tttctaactc tatttaaagc agttttcttt tcgataacac ttattctttt cttagctgat
    88261 tttatatttg ccaccgtgtt cacctccctg tattttttta tcatattcat cgtcaacata
    88321 ttagatttta acagaaataa atctaaaaat caaggattat tatttatata ttttaataat
    88381 gttttttatt ttgatttttt agactgtaga ttgtgtataa ataatttgca atatcttgtt
    88441 tttaggttgg tatattttgt gttttaaata ttttgacata tataaattaa tattttattt
    88501 ttgtaacaaa tattttgaga taatacaaat tattaacata cattttgata gtatttccaa
    88561 taattataag ataatacaag aaattactca tttttgtgaa tttaataaaa aattataaaa
    88621 atacagagga tacagcagat aagttgatat catatataga tgaaaattgc agtggtcatc
    88681 ttttcgcttt gtgtggggta tcacttggtg gtcaaattgt catggaactt ttatctcgaa
    88741 aacctaatat tactaaaaaa gcaattattg atggtagtat ttgctaccca agacctctta
    88801 tggcaaggtt ttgtattact ggtattcgat tttttggagg acttttattt agtaagaagg
    88861 cttgtcgctt tcaaattgct atgatgccaa aattgttacc tgaaaatatg caatatccag
    88921 atgaaataaa agcatattat atgacagata tgccacatgt aagaaaagaa acattctata
    88981 atatgtatcg tacttacatg atgaactaca tacttaaaga aaatgttaaa aaaaccacag
    89041 cacaagtaat gtactggtat ggagaaaaag aaatgaagtg cgttaaaaaa tctgcaaaaa
    89101 tgtttcagtc ttatgtaccc tcttgtgaga tttatgaagc taagggctat aatcatgggt
    89161 atttatcgct ttaccttcca aatgaatggt tggaaattgc ggaaccattt tttcaaaagg
    89221 aataaaggtg ttaggtgatt attgtataat tattgctgtt tttttatata gtaaataaat
    89281 taggtatgat ataaaaaaat tattttggtc aatatattag tgaaagctta ataggaaaat
    89341 tataaataga ttaaaggtag ggcctatata aatagtttct acctttttct gtttgtaaat
    89401 aaatgataga taagaaagtt tactgacaaa tcactgacca aacccaattt tcttacattg
    89461 aaagccttaa ttttacttgt tttaaataaa tttacaattt cttgttataa aatactaaat
    89521 tttgttaaca attataatta gcatttaatt tatactggag gtttatatga ttaatgtaag
    89581 aacagattta gctttagaag ctagtgaaat gtgtgaaaag tctcaagaag gaagtagcat
    89641 tcctggtgta aaaatagaaa ctaaagaatt agaaaattgt attgtaacta aggttgaagt
    89701 aatagacgaa caaggttcag aaataatgaa taaagatata ggaaaatata taactctgga
    89761 aagtaatctt atgaagtttg atgatgatga atcaagagaa gaaatgataa gttatctaaa
    89821 agatgaactg gtagacatat ttggacaaga cgaaaataaa aaaacgttag taatcggtct
    89881 tggaaataga aatattactt ctgatgcact aggacccaaa agtgtatcta aaacacttgt
    89941 aactagacat ctttttaaaa attataataa agattatgat gatgatttta ctgaggtatc
    90001 agctttaagc ccaggagtta tgggagttac tggaatagag actagtgaaa tagtaaagtc
    90061 attggttgaa aaagtaaaac cagatagagt agtagcaata gatgcattgg cttcgagaaa
    90121 aatggaaaga gtaaactcta ctatacagat atcaacagca ggaatatcgc ctggtggagg
    90181 tgttggcaat acaagaaaat ctctaactaa agaaacttta ggtgtggatg ttattgcaat
    90241 aggagtgcca acagtggttg atgcagcaac tcttacaata gatgttttgg acatggcaat
    90301 agacaattta atagctcagt cagaagaaac agaaagtttt tacgaaatgt tgaaaaaact
    90361 taaagaagaa gaaaagtatc atctaataaa agattcatta gacccatatg acaagaactt
    90421 gatagtaaca ccgaaggata tagatgatac aatcgaaaat ctatctataa taataagtga
    90481 aggtctaaat aggtctttac atccaggtag attggtataa aataaggagg agcaattatg
    90541 tttaaaaaat gcattaaagt agtaaccttg acttttatat tagcatgcat tttaccagga
    90601 aaatcattag ctttgaatca ggatgatttt ttaaagtttt tagtaaattc atcttatcca
    90661 gaagctaaag tcgaaggaaa tgatacagaa gataaaaaga ataataaaaa taaagaaaca
    90721 agcaaagaaa ataaggaaga aagtaaagaa gaaaaaacta aatctaaaga tgcaagtaaa
    90781 gttgataata aaaaagagag tgaaaaagaa tatataaaac tttatgttgg taaagaaaat
    90841 gttccagata ttgagtcaaa aaattcagac acaactgaaa ctaacgcaac atctagttca
    90901 gattataagg atgacctaag agtaactaaa gaaaatccaa gaattttgat atatcatact
    90961 catggatgtg aaacttattc aaattcacca gatggaaact accattcaag agataagaaa
    91021 aattcagtaa tggaagtagg aagtgcatta actagtgctt tagatagcaa gggatggggt
    91081 gtagttcata caactaagta ccatgactat ccatcttata ataactctta tgcaagtagc
    91141 ctaaaaacaa tacaaagtat attacctaaa tataattcag tggacatagc gatagactta
    91201 catagagatg ctagggattt aactaatcca gccactaagg aaaaagacca tttaaaatat
    91261 acaactatga taaatggaga aagggtatca aaattcttct ttgttgtagg aggtaaaaat
    91321 acaaatagaa aacaacttag agctttagca gaagacataa ctgcttttgc tgagaagaag
    91381 tatcctggtt tggtatctcc aatagtagaa aaagactatg ctagattcaa tcagtttgca
    91441 gttaagaatc atatgttagt agaaataggg aataacgcaa caagcgtaga agaatctaag
    91501 gctactacaa agtatctagc tgaaattttg gatgaatatt ttaaacaaaa aaattagagt
    91561 tttaaggtat aattaggagc atgttaaatg agccgattag aaaaaaatat agaaagtaaa
    91621 agtaaattaa gaaaatacaa gtatattatg agaattatgt ttttgattac tatgattata
    91681 tgcacatcag tttgtgtatt tatagtagat agtaatgcaa aaagtatgct aggaatgaaa
    91741 caatatgatt ttcccaatat taaatttgat ataacaaaat ttgattttga tataccgaac
    91801 tttgatatac atgaaatcat aagaaaattt aataagtagt aataaatgaa taaggtttat
    91861 tgatgaaaat aagccttatt ttagttatat atctttaatg tataaaataa aaattcacta
    91921 actgtatttt ataggattta ctttaagttt atgatattat ataatattta gtgttagact
    91981 tgataatcca catataatgt ggataatttt gtttagtgcc aattagttta tattcaaaaa
    92041 ttttaaattt ggtatataaa gagtttttag ataatgtaaa ataataacta taagaataat
    92101 caagaggagg gaactttaag gtggacaata aacaaagtag aactagaaat tttagtataa
    92161 ttgcacatat agaccatgga aagtctacct tagctgatag attaatacaa caaactgggc
    92221 ttgttagtga aagagacatg aaaagtcaat tacttgacaa tatggacctt gaaagagaaa
    92281 gaggaatcac tataaagctt caaaacataa gattaatgta taaagcgaag gatggaaacg
    92341 aatattattt aaatcttata gatacacctg gacatgtaga ctttaactat gaggtatcaa
    92401 gaagtttggc tgcatgtgag ggagctttat tagtagttga tgcagctcaa ggtgttgagg
    92461 cacaaacttt agctaatgtt tatcttgcta tagaccaaga tttagaaata ttaccaataa
    92521 taaataaaat agatttacca agtgcaagac cagaggaagt aaaaaatgaa atagaagatt
    92581 taatagggct tgactcaagt gaagcacctc ttatctcagc taagactggt ttaaacatag
    92641 aggatgtttt agaagacatt gtaaaaaatg ttcctccacc taaaggagat aatgaagctc
    92701 cattaaaggc attaatattc gattcttact atgatgctta caaaggtgtt gtagcctatg
    92761 ttagagtatt tgaaggaact gttaaaaagg gtatgacaat aaaaatgatg aataccaata
    92821 aaaagtttga ggtaactgaa gttggtgtta tggctccagg tcaaactgaa cttagtgaat
    92881 tatcagcagg tgatgttggt tatattgcag ctagtataaa agatataaga agttgtcgtg
    92941 ttggtgatac aataacagat tcaaataatc ctacagaaga acctttacca ggatacaaaa
    93001 aagctactcc aatggtatat tgtggtatat atccaggaga aggagaaaaa tatgaaaatg
    93061 ttagagatgc tcttgaaaag cttcaagtaa atgatgctgc acttgaatat gaagctgaga
    93121 cttcagccgc actaggattt ggttttagat gtggtttctt aggtctttta catatggaga
    93181 taatgcaaga aagacttgag agagaattta atcttgatat aattactaca gcaccatctg
    93241 ttatatatag agttacaaaa atggatggag aagtcgtaat gatacaaaat cctgcaaact
    93301 tgccagaacc atctgagata aagatgatag aagagcctat agtaaaagga gatataatag
    93361 ttcctaaaga ctatgtaggt gttgttatgg aactttgtca ggaaagacgt ggaaatatgt
    93421 tgaacatgga gtatatagat gagagaagag taatgcttca ctatgacctt cctctcaatg
    93481 aagttgttta cgatttcttt gatgccttaa aatcaagaac tagaggttat ggttctcttg
    93541 attatgaggt taaaggttat gtagcatcta cacttgtaaa actcgatata ttaattaata
    93601 aagaacaagt ggatgcactt agttttattg tccatgaaac acgtgctttc cctagaggaa
    93661 aggcaatgtg tgagaaatta aaaggggaaa ttccaagaca tcagtttgct ataccaatac
    93721 aagctgctgt tggtaataag gttattgcaa gagaaacaat aagtgctcta agaaaagatg
    93781 tccttgctaa atgttatggt ggggatatat ctcgtaagaa gaaacttctt gaaaaacaaa
    93841 aagaaggtaa gaagcgtatg agacaaattg gttctgttga agttcctcaa aaagcattta
    93901 tgtctgtgct taaattagat gaataaatcc ttataaattt agataaagat atttaaaagc
    93961 tagagtgatt ttagaattat ttctaaatta gtctagcttt tttatggtat attttaagta
    94021 aactcataaa gaatataagt aagaatatta aagaagaata aaaaggtgat atttatgatt
    94081 aatatagaaa ttcctaaaaa agtagattat ataattaaag aattagaaaa gaatggttat
    94141 gaagcttata tagttggagg atgtgttaga gattgtttat tagaaagagt tccaaacgat
    94201 tgggatataa caactagtgc tagaccagaa gtggtagtag aattatttga aaaaacaatt
    94261 ccaactggta tacaacatgg aactgtaaca gttatggttg aacatgaacc atttgaagtg
    94321 acaacttata gaattgatgg aaattatagt gatggaagac atccagattc aatagaattt
    94381 acaaataaca tagttaagga cttatcaaga agagatttta ccatcaattc aattgcatac
    94441 aattcagaaa caggattagt cgacccattt aatggatatg aagatataca aaataaatat
    94501 atacgttgtg ttggaaatcc agtagatagg tttgaagaag atgcgcttag aatgcttaga
    94561 gcagttagat tttcagcaca acttaatttt aatatagatg aaggtactga gcaaagtatt
    94621 cataaaaaat cagatttgat aaaaaatgtt tctattgaaa gaatccagac agagtttaat
    94681 aaaatcttag tatctgattc atctaaatta aacctattaa aatcaacagg tttgttgaaa
    94741 tttataattc ctgaaatatg tgaattggaa gatgtcactc aacacaatcc atatcatatc
    94801 tatgatgtac aaaaacatac tttaatagct acagaagtaa ttgaagatga actgtattta
    94861 aaacttacaa tgttgtttca tgatttaggt aaaaaagtaa ctaaaacaac tgataaaaat
    94921 ggtgttgacc atttttatac tcatagtaga gaatctgtaa agattgcaaa gaagattttg
    94981 aaaagactta agtatgataa ttatactatt aataaagttt tgatattgat acaatatcat
    95041 gattatagaa tagaacctaa aaggaagata attaaaaagt tattaaataa acttgaagat
    95101 gttgaattat ttgaagattt aataaaagtt aattgggctg acacacttgc caaaaatcca
    95161 aaatatgcaa aacaaaagat attaaatctt attgagtgtg aaaaagaatt taaacatata
    95221 ataaatcaaa aggagtgctt taatcttaaa gatttagcta ttaatggaaa agatttgata
    95281 tctataggta taaaaccagg taaagacata ggacatattt taaataatat gcttgaaata
    95341 gttataaata atccagagct aaatgaaaaa gaaatactaa aagaaaaggc attaaatata
    95401 tatacatttt agattcaaat ataaaaaatt taatagattt aagaaatata gaagaaaata
    95461 tgtatttaga taaaataaat aatttttaga gaatatttta gagattacga ttgtatgagt
    95521 tttaaatgca tagggattta ctctaggatt atagactaat ataaaaaaaa actttgggaa
    95581 tactaaaacc ataaatttat aaaattaata ttttatatac tgtaaaacag tgaggaggaa
    95641 cagtatgcat actcaactac aaaagactat tggtctttca gcagctcttt ctactgttgt
    95701 aggtatggtt ataggttcgg gagttttttt taagccacaa gcaatataca ctacaactaa
    95761 tggagctcca gggctaggta ttatagcatg gcttttaggt ggttttataa caataactgc
    95821 tgggcttaca gctacagaaa tttcagctgc tataccgaaa actggtggta tgatgattta
    95881 tatcgaagaa atatatggag aaaagttagg ttttttaact ggatggatgc aaactgtact
    95941 atttttccca ggtacatcag cagcactagg agtaatattt gctcaacaag catctgaact
    96001 tttaggaatg agcccaaata atatggcaaa tgtacttcct atagcgattg gagttatact
    96061 atttttagca ttattaaata taataggttc atctttagga ggaaaagttc agacagtagc
    96121 taccattgga aagatgatac ctttaatttt aataataatc tttggattta ttaaaggtca
    96181 aagtagtgaa gtgttaaatc catttgtagg agatggtgta aatgcatcaa atgcacttgg
    96241 acaagtatta atagctactt tgtttgcata tgatggttgg ataaatgttg gagctatatc
    96301 aggagaaatg aagtctccag agaaagactt accaagagca atagttggtg gtttatcatt
    96361 agttatggca gtttatatta taataaatat agcttatctt tgggtagtac cagcaagtga
    96421 attagcaaca gttacttcac cagctacatt agtagcaaca agattgtttg gaaatatagg
    96481 tggaaaagta ataactatgg gtatattaat atcagtattt ggcacattga atggatattt
    96541 attaacaggt tcaaggatac cttatacatt agctgaaatg ggaactttac cagcatctaa
    96601 agctctttta aaagtaaatt ctggaggttc tcctgtaaat tcaatactac ttataactgc
    96661 gttagcatgt gtatatgcat tatctggtca atttaatctt ttgacagatt taactatatt
    96721 ttcaatatgg gtattttatg tattaacttt tataggtgtc atgaggctta gaagacaaaa
    96781 gccagattta tacagaccat atagagtccc tttatatcca ataataccga ttatagctat
    96841 attaggcggg ctgtttgtaa taataaatca aatattaact tcaacagtta tatctctagg
    96901 cggaatattt ataacactat taggtttacc agtttattat tatatgaaaa aaagataact
    96961 acttaattta agttagatga atttgggtaa aagtaaaaat taacttttat ccaaattttt
    97021 tatactatta cacaatataa gtattatata ttacttgatg tgctattttg tttgatttat
    97081 aatttagtaa ttgatgtttt aagataattt aagaaatgag gaataaaaaa tgctaggact
    97141 ttatgtacat attccatttt gtgtgaaaaa atgtaagtat tgtgacttta attcttataa
    97201 aatggacata gatttaaaaa aaagatatat agaagattta aaaatagaaa tggaattata
    97261 tagtaataaa ttatataaag ataataaata taaaaataaa gaatgttgta gtctaaataa
    97321 aaatgacaaa ataacgagta tatttgtagg gggaggtaca cctagtatac taacatctga
    97381 tgaaataaga gaagtattta tgagtataaa agaaatgttt tacatagatg ataatgcaga
    97441 aataactata gagtgtaatc ctggtacatt aacattagaa aaattaaaaa ctatgaaaga
    97501 tattggtata aatagactta gtatagggct acaagctatt caagaaaagc atttgaattt
    97561 tataggaaga atacatactt atgaagaatt tgagaaaaac tataaagatg cattaagtgt
    97621 aggatttaaa aatattaata tagatttaat gtacagtctt ccaaatcaaa ctctatgtga
    97681 ttggaaggaa actcttgaaa aagttgtaca cttaaatcca acacatatat cagcttattc
    97741 tcttatacta gaagaaggca ctgaactata caatatgtat gaaagtaata aatttgaact
    97801 tatagatgaa aatatagata tagaaatgta tgaatataca ataaactacc taatgtcaaa
    97861 aggatataat caatatgaaa tatcaaatta ctcaaaagaa ggctttaatt gtaagcataa
    97921 tattttatat tgggaatgta aaccgtatat agggattgga gcaggagctt ctggctatat
    97981 taatgagaac agatacaata atgtagaatc tttagaagac tatcatttaa gtttggtaaa
    98041 aagggaaaaa ccaatacaag aaaatgaaat tctttctgag aaagatatga tagaagaaaa
    98101 gatatttatg gggcttagaa tgaataaagg tataaaattt gaagatttca aaaaaaaatt
    98161 tggaatagat tttaaagata agtatagtaa gcaaatagaa atgctatcag ctagaaagct
    98221 tataaatcag agctttgaag gtatacaatt aactcaaaaa ggaagagaaa tctctaatag
    98281 tgtatttata gaatttatgg aataattatt aaggtgttga caaaataaaa ttataatggt
    98341 atataatata tataatcttt ttagcactcg aacttagtga gtgctaacag ctaggaggta
    98401 taataatatg gaattaaatg aaagaaaatt aaatatcctc aaagctatag ttaaagatta
    98461 tatagaaaca gctgaagcta taggttctag aacaatatct aaaagacatg atttaggtgt
    98521 tagtgctgct accataagaa atgaaatggc tgaccttgaa gaattagggt atttaattca
    98581 gcctcatact tctgcgggca gagttccatc tgaaaaaggc tataagttat atgtaaactc
    98641 tcttatgagt aaaagcgagt tggatgataa tgataagatt cttattgaac aatgtatgaa
    98701 tcataatata aatcatataa aagaattgat tcatgaaact tctaagctat tatctcaact
    98761 aacaaactat acaactgtag cagttactaa gagtttagta aatcaaagtg ttataaagca
    98821 catacagttg gttgctatga atgataataa tattttactt atagttgtaa cagataaagg
    98881 ggacttgaaa aaagctaacc ttacaactaa tgtatattta gatcaatcta agttaaattt
    98941 gatttctgat aatcttacaa ggaagctctt aggtaaaagt ataacagatt tggatgataa
    99001 tctaattgct tttattaaat acgaaataag tgagtattct gggcttatag atgagctttt
    99061 aaatgctttg aactcaaata tgaaagaaga agatttttct ctatcattaa atggagctac
    99121 taacatattt agttatccag aatttaatga tgtattaaaa gcaaagtcat ttttaaatat
    99181 gttggagaaa aaggaaacaa tagctgacat aattaaatca aagggaatac aaaaagacaa
    99241 tctaaatata ataattggta gtgataatga ttgtgaactg gcacaggatt gtagtatagt
    99301 tacagcaact tataatgtag atagagactt ggttggacga ataagcttca taggtcctac
    99361 cagaatggat tatgctagaa tttactctat aataaattat atgagtttat taattaatag
    99421 aaagtaaaga aattttaaat tgcgaggtgt aaagtcttgg ataaaaaaaa tgagcaacag
    99481 gaagtaagag aagaaaatga tacttctatt aaccaagaat cggaaactca agtagagttg
    99541 gaagaggaag ttgttaatga agaatgtgaa acatcaaatg aaaaaactga tgaaaaagaa
    99601 gttgatgatg aaaatgtaac agatataaat tctaagttag cagaaaaaaa attgcagaat
    99661 gagttggatg aattaaatga taaatatcaa agacttcaag ccgaatatgc aaattacaga
    99721 agaagaactc aacaagagaa agagacaata ggtgtatttg caaatgaaaa aataataact
    99781 gagttgatac cagttataga tagtatggaa agagccttag atgcatgtga agataaggaa
    99841 gatactatgt ataagggtat aagccttgta cataaacaat taatagacac tttagtaaaa
    99901 tttggagtag aagaaataga agcagaatct aaggaatttg accctaattt acatctagca
    99961 gttatgcaag aaagtgtaga tggaattgaa gcaaaccaaa tagtaatggt acttcaaaaa
   100021 ggatataagc taggaactaa agttgtaaga ccttcaatgg ttaaagtttc ttgctaagta
   100081 taaattaaag gttacattat ttaacctaat ataaaatatt aaaataagta aaacttaatt
   100141 atataattac tcgaggagga ttttagtcat gggaaaaata ataggaatag atttaggaac
   100201 aacaaattca tgtgttgcag tgttagaagg tggagaagca caaataatag caaatagtga
   100261 aggtatgaga actactccat cagtagtagc atttacaaaa gatggtgaaa gaatagttgg
   100321 agaacctgca aaaagacaag cagttacaaa tgcagataaa acaataactt ctataaaaac
   100381 tcatatggga actgattata aagtaaatat agatggaaaa tcatatactc cacaagaaat
   100441 atcagcaata atattacaaa aattaaaatc agatgcagaa agttacttag gacaaacagt
   100501 aacagaagca gttataacag ttccagctta ctttacagat gctcaaagac aagcaactaa
   100561 agatgctggt agaatagcag ggcttgatgt taagagaata ataaatgagc caacagcagc
   100621 agcacttgct tatggtatgg ataaattaga ccaagaaaag aaaatattag tatttgactt
   100681 aggtggagga acttttgacg tatctatact tgaaatagga gatggaactt ttgaagtttt
   100741 agctacagct ggtaacaata gattaggtgg agatgacttt gaccaaatag taatagatta
   100801 tttagcagag gaatttaaaa aagctgaagg tgtagattta agaaatgata aaatggctct
   100861 tcaaagatta aaagaagcag cagaaaaggc taagaaagaa ttatcatcaa caatgagttc
   100921 aaacataaac ttacctttca taactgctac agcagaagga ccaaaacact taaatataga
   100981 cttatcaaga gctaaatttg aagaattaac tagaggttta gttgaaaaaa ctatggaacc
   101041 aactaagaca gctttacaag atgcaggact ttctacaggt gatatagatg atgtattatt
   101101 agtaggtggt tctacaagaa taccagcagt acaggaagct gttaagaagt ttataggaaa
   101161 agagcctcac aaaggtataa acccagatga atgtgttgca gcaggtgctt ctatacaagc
   101221 tggagtttta gcaggggatg ttaaagactt attattacta gatgttactc cattatctct
   101281 tgggatagaa actatgggta atgtaatgac taagataata gaaagaaata ctacaatacc
   101341 aactaagaag tctcaaatat tctcaactgc tgctgataat caaacagctg ttgatataca
   101401 cgttcttcaa ggtgaaagaa gtatggctta tgacaataca actttaggaa gattccaatt
   101461 aacagatata ccaccagcac aaagaggaat acctcaaata gaagttactt ttgatataga
   101521 tgcaaatggt atagttaatg tttcagctaa agatttaggt acaggaaaag agcaaaaaat
   101581 aactataaca tcaaacacta atttatcaga agcagaaata gagcaaaaaa taaaagaagc
   101641 agaaatgaat gcagaagctg acaaacaaaa gaaagaaaaa atagaagcat tcaatcaagc
   101701 tgaatctact atatatcaaa ctgaaaaaac tttaaatgaa cttggagata aaataagttc
   101761 aagtgaaaaa gaggagatag aaaaagctat agcagactta aaaactgtaa aagataatca
   101821 agatgctaca gcagaagaac ttaagaaagc tacagatgaa gtaatgacta agttccaaaa
   101881 agtatctcaa gagatgtacc aaaaagcagc tcaagagcaa caagcagcac aaggtgcaga
   101941 acaagctcaa gacaatggac ctaaagatga caatgtagta gatgctgact ttaaagaagt
   102001 ggatgaagat aaataagcta tataatatgt aacactaaat gatagttaga gcatatatga
   102061 tttgtgaaaa tcatatagat gttaaagata tatggacaat acacatcata aagaatataa
   102121 tatatcatag attatataac ttaaagtaga atataagaat taatgatagc ttgtagttta
   102181 ttattctaca agctatcgtt ttgtaaaatg aaggtggtgt cagtttttga gtacaaaaag
   102241 ggattattat gaagtcttag gtatcagcaa aggtgcagaa gctcaagaga taaaaaaagc
   102301 ttacagaaaa ttagcaatga agtaccatcc agatagaaat cctggagata aagaagcaga
   102361 ggaaaaattt aaagagataa atgaagctta tgaagtctta tctgatgata caaagagaaa
   102421 aacttatgac cagtttggac atgatgggct aaatggtcaa ggtggttttg gtggtcaagg
   102481 aggatttggc ggtcaaggtt ttggtggttt tgaagatatg ttcggagata tatttggtga
   102541 catgtttgga ggaagcttcg gaggaggaag aacaagaaga agaggacctc aacgtggtgc
   102601 agatataaga caaagtgtta ctatatattt tgaagaagct gcatttggta aaaagatgtc
   102661 tataaaagta aatagaagtg aagagtgtga agaatgtaat ggaactggag caaaaccagg
   102721 aacatcaaag aaaacttgtt caacttgtaa tggaacaggt caagttagaa ctgttcaaag
   102781 aactcctttt ggtaatatag caagttcaag accatgtagt acttgtaatg ggactggaga
   102841 agtgattgaa tctccatgta gtaaatgcca tggaactgga aatacaagaa aagttaagac
   102901 tatagaagta gatatacctg ctggtataga tgatggtcaa atgataaaac tttctggtca
   102961 aggtgaagta ggagaaaaag gtgctccaag aggagactta tatattgtag ttaatgttaa
   103021 gtcacatcca ctatttacta gagatggaaa tgatatttat tttgaaatgc caattacatt
   103081 tgttcaagca actttaggtg atgagataga agtacctact ttggatggaa aagttaaata
   103141 tagtgtacca gaggggacac aaactggaac tgtatttaga cttaaagaaa aaggaatccc
   103201 tagaattaga ggtaattcaa gaggagacca atatgttaag gttgtagttg aaattcctaa
   103261 aaaattaaac gataagcaaa aagaactatt gagagaattt gcgaaggagt gtgggtcgaa
   103321 cgtccacgaa aagaagaaaa ccttcggaca aaagatagaa gatatgttta agaaaaagta
   103381 gttaaagtag ccaatatata atcatatttt tgaaatctta gttatttata agattgtcaa
   103441 aggagatatt atgattttta tattggctat ttttgtataa aaaataaata tgcataaaat
   103501 aaaactgaat ataaataatt ttctgaaaaa tacttgtcct aaaatatata atatgctata
   103561 atataatcaa ataaaagaaa ggggtgattc cagtgggaac ggatgtggca ctgccagatg
   103621 acgaagaaaa ctttattgta atctacaaaa taaaattaga tgcttttagt gctagattaa
   103681 gtactggaaa aactcatgag ctgggataat tattataatt acctagactt aaatttttag
   103741 tagtaaaata gtaatattat atagacaagg tatctaattt ttaaatcttt tgtatgaatt
   103801 aaaattttta taaaggatat atctgattag aatgtaatta gggaaaccta gttgtaaatt
   103861 gcttttagta tatacatgtg taaagaaata tgtatatggt attggttatt gtgctagatg
   103921 catatgtaaa ggaatatgta tttagttgag tatatgtaaa gaaatatact tataatctat
   103981 gaaaaaattt tagtataaat tgctaaaaca ttgagattgt tttttataga aagttagttt
   104041 ataccaatta aaaatgtgct taagatttgt ttgatgttta attataaata agattgtaga
   104101 taaaaaaata agtagagaca aaggtttaaa atacttgatt taaatatagt ttgttttgaa
   104161 cacttgccaa attaaccaaa ttaaaataat taataaaata gacatcttct catagtaaaa
   104221 tatactgtga gaggatgttt ttgctttgtt cataaacttt tatgaaaaat ttgcatagtg
   104281 tcacatttta atatactata tatataataa aatatagata aaattaaatg attcaaaaga
   104341 gaaaggtgaa aagagatgta ttatataggt gtagacatag gaggaacagg tatacaagca
   104401 ggagtagttg ataactatgg gaagataatt tttaggtcag agtgtaaaac agtaattgaa
   104461 aaaggctttg aaggaatact taatgacata aaaataatga tttataagtt gttggaagat
   104521 aataaactta ctatgagtga cataaaatct attggatttg gtgttccagg ttttataaat
   104581 aaagaaggat tagtaacttg tgtaaattta aaatggaata aaaaagcttt taataaagag
   104641 ttaaaaagaa gatttccaga tgttgaaatt catggagaaa atgatgcaac agtagcagca
   104701 cttggagaag caaagtttgg aagtatgaaa ggtgctaatg ttggagtatt atatacttta
   104761 ggaactggtg taggtggagg aatagtaatt aatcaaaagg tcttttctgg agcacatgga
   104821 ttgggttcag aaataggtca tcaaattata ggagaaaact attttaattg taattgtgga
   104881 aataatggtt gtgtagaaac tttttgttca gcaactgcaa ttataaagta ttctcaaaag
   104941 ctgatagaag aaggagaaaa gagtaggatt ttggatttgg cagagggcaa tttagaaaat
   105001 gtaaatgcaa agatggtgtt tgatgcatat agagaaaatg atttagtggc aattaaagta
   105061 ataaatagat ttaaagaata tttggcaaaa acttttgcaa atacaataaa ttctttagac
   105121 ccagaaatta tatccatagg aggaggtatt tctaaatcta gcgatataat acttgatggg
   105181 atagaagatt tagtaagaaa atttgtatta tacaaaacag aagatatagc tacaattaca
   105241 tgtgcaactt taggttcaga cgcaggaatt ataggagcag cttttttata aagtaaatga
   105301 actgcttatt ggaggcggga tatatgagta aaacaaatgc tagaagaacg ctttttttga
   105361 tagccatagg ttcaggaact atgctgaatc ctcttaattc ttctatgatt tcacttgctt
   105421 tacatagtat acaaaatgat tttcatatta gttttacaac tgtatcttgg attgtttcag
   105481 cattttacct agctagtgct attgcacaac cagtttcagg taaaatagga gatttaatag
   105541 gtaggaaggt cttatttttg agtggtttga tgcttgtaat tttatcagca tccatagtgc
   105601 cacttgttca atcattcttt atattgattt ttataagagt aattcaggca attggaacga
   105661 gtacactata tccatctgga gttgctctta tacaaaataa tataaaagaa agacagtctt
   105721 ctgcattagc agttctaacc atttttgctt caactacagc aggattaggt ccaacgcttg
   105781 gaggattatt gttggattta ggaggatggc atgctatatt tcttgtaaat atacctgttg
   105841 ttttggtttc tatatgctta gggtattttt tattcccaaa agaagtaaaa gaaaagaaat
   105901 ctataaaaga aactctgaaa aatgttttgt caagattaga tattattggc atacttctat
   105961 tttcaattgc aatgattttt atattattat ttttgctatc tatgaaggag tctttcaact
   106021 tagaacaact tgtatttggt ataatactga tgtatctttt tatttggcat gaattgagaa
   106081 caaaattacc atttatagat attaagcttt ttgtgagtaa ccctaaattg tcaaaagttt
   106141 acttgcaatt tattatatta aatttcttta attatatttt gttttttggt cttcctagtt
   106201 attttcaaga tgcattacac tatagtgcaa aatcgactgg attatttatg ctatttatgt
   106261 ctggtatagg tatatttata tctccattaa ctggaagatg gatagataaa tctggaacta
   106321 gatttcctct tgttacatca tcaatcttta tgtttattag tgcagtactt ctttcagtag
   106381 tttttattca tataccagta ataggaaaag gtatcatatt atcattagca ggtattagtt
   106441 atggagttgg taatgtagcc ctgcaatcct ctatgtttga agaaagtcct cgtgacagta
   106501 tagggacagc ttctggcctt tttcaaacta gtcgttattt aggttctatt ttagcaactg
   106561 ttttacttgg aatggtattt gaagtaaata taacatcaga acaatttcag atattaggtt
   106621 atgtgatggt ggtcttaggt acaataagtt ttttattaaa ttttatacta aagaaagaat
   106681 taagaaaagt agaatagtgg atttatggat ttaataagtc taataactga taagtttaaa
   106741 aacattgttt gtaaaatata actagtttga tatttattaa ttctaagctt tgaagcatag
   106801 agtactcgat aagtatacaa tattttgaat taaaattaag cagaaatttg aactagtctt
   106861 tcaaatctct gcttaattta gtggttaaat ttttttatag agaaaataag atttgacact
   106921 cagataaaaa atcattgcat tttcaaaatt ctttaaatca aacccaagta tctcattaat
   106981 cttttccaat ctatatacta gcgtgtttct atgtaaaaac atactagttg atgtcttaga
   107041 aatatttaaa tcattattta taaattttaa tcctgtatat agaagttctt catcaataga
   107101 tttaatctta ttaaaatcta ttaatttatt gagtatattg tcctcattaa ttaaatctaa
   107161 ggttttatat ctaataaggt caaacaaatt taaaaactta ttttcagcgt tgtcttttat
   107221 aatatgaggt agtaaatcag aacataactg taatctaaaa tcaaaatcag ctttactatc
   107281 taatttacca agataaaaaa tataagtact ttgataagtt tcagtttcaa ttatattttg
   107341 tgtagttaca ttaatatcta agttatattt agaatttact ataa
//
LOCUS       DBGJFK010000004       105685 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.004, whole genome shotgun sequence.
ACCESSION   DBGJFK010000004 DBGJFK010000000
VERSION     DBGJFK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 105685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105685
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.004"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            118..864
                     /gene="cdtR"
                     /locus_tag="ACOIAP_000328"
                     /pseudo
     CDS             118..864
                     /gene="cdtR"
                     /locus_tag="ACOIAP_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906004.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
     gene            1254..2645
                     /gene="cdtA"
                     /locus_tag="ACOIAP_000329"
     CDS             1254..2645
                     /gene="cdtA"
                     /locus_tag="ACOIAP_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin enzymatic subunit
                     CdtA"
                     /protein_id="HGZ2637249.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSEKV
                     CNTTYKAPIERPEDFLKDKERAKEWERKEAERIEQKLERSEKEALESYKKDSVEINKY
                     SQTRNYFYDYQIEANSREKEYRELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTEN
                     QNEISLEKFNEFKETIQNKLFKQDGFKEISLYEPGKGDEEPTPLLMHLKLPRNTGMLP
                     YTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKA
                     NYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKR
                     EPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKPENIDAFKSKWEGQTLSYPNFISTSIG
                     SVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKISKIDSYKDG
                     AITKLIVDATLIP"
     gene            2698..5328
                     /gene="cdtB"
                     /locus_tag="ACOIAP_000330"
     CDS             2698..5328
                     /gene="cdtB"
                     /locus_tag="ACOIAP_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin binding subunit
                     CdtB"
                     /protein_id="HGZ2637250.1"
                     /translation="MKVQMRNKKVLSFLTLTAIVSQALAYPVYAQTSTSSHSDNKKEI
                     INEDILTNNGLMGYYFTDEHFKDLKLMAPIKDGNLKFEEKKVDKLLNKDKSNVKSIRW
                     TGRIIPSKDGEYTLSTDRDDILMQVNNESTISNTLKVNMKKGKEYKFRIELQDKNLGS
                     IDNLSSPNLYWELDGIKKIIPAENLFLRDYSNIEKNDPFIPNNNFFDPRLMSDWEDED
                     LDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEK
                     ASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTES
                     NTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINAN
                     VRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALN
                     TMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYIS
                     QIDSISASIILDTENESYERRVTAKNLQNPEDKTPELTIGEAIEKAFGATKKDGLLYF
                     NDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDD
                     YNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSKLKPYKRYVFSGYSKDPLTSN
                     SIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITE
                     LNSTPEILNEPEVKIPTDQEIIDAHKIYSADLNFNPSTGNAYINGMYFTPTQTNKEAL
                     DYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYK
                     KLRIYAITPDDRELLVLSVD"
     gene            complement(5980..6981)
                     /gene="trpS"
                     /locus_tag="ACOIAP_000331"
     CDS             complement(5980..6981)
                     /gene="trpS"
                     /locus_tag="ACOIAP_000331"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGZ2637251.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(7004..7702)
                     /locus_tag="ACOIAP_000332"
     CDS             complement(7004..7702)
                     /locus_tag="ACOIAP_000332"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGZ2637252.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(7745..7985)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8076..9479)
                     /locus_tag="ACOIAP_000333"
     CDS             complement(8076..9479)
                     /locus_tag="ACOIAP_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGZ2637253.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKINMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     gene            9976..11052
                     /locus_tag="ACOIAP_000334"
     CDS             9976..11052
                     /locus_tag="ACOIAP_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGZ2637254.1"
                     /translation="MKTQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(11155..11997)
                     /locus_tag="ACOIAP_000335"
     CDS             complement(11155..11997)
                     /locus_tag="ACOIAP_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGZ2637255.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNKTFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKIEVIDSLSGSIGIGQLVLKAAILIEEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEVGSVMGTYTSKGAIL
                     ITAI"
     gene            12181..12753
                     /locus_tag="ACOIAP_000336"
     CDS             12181..12753
                     /locus_tag="ACOIAP_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2637256.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKNDIIYDIADTHLEVITSAILNCVKNVKSKNSQIDMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERMRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLINHWI"
     gene            complement(12916..13188)
                     /locus_tag="ACOIAP_000337"
     CDS             complement(12916..13188)
                     /locus_tag="ACOIAP_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637257.1"
                     /translation="MLRERFVVRNHHNPHTSECCGTGGKGCCGGDNNEHSHQHSHSHG
                     HEHEHINGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDEHTHEHK"
     gene            complement(13302..14174)
                     /locus_tag="ACOIAP_000338"
     CDS             complement(13302..14174)
                     /locus_tag="ACOIAP_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2637258.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIVAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(14461..17568)
                     /gene="ileS"
                     /locus_tag="ACOIAP_000339"
     CDS             complement(14461..17568)
                     /gene="ileS"
                     /locus_tag="ACOIAP_000339"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGZ2637259.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEIYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAERAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVVKK"
     misc_binding    complement(17660..17892)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18067..18594)
                     /locus_tag="ACOIAP_000340"
     CDS             complement(18067..18594)
                     /locus_tag="ACOIAP_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HGZ2637260.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCKENTA
                     LREKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(18629..19414)
                     /locus_tag="ACOIAP_000341"
     CDS             complement(18629..19414)
                     /locus_tag="ACOIAP_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmH/Sll1252 family protein"
                     /protein_id="HGZ2637261.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITRKGKIKVQARLIV"
     gene            complement(19424..19681)
                     /locus_tag="ACOIAP_000342"
     CDS             complement(19424..19681)
                     /locus_tag="ACOIAP_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGZ2637262.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(19700..20158)
                     /locus_tag="ACOIAP_000343"
     CDS             complement(19700..20158)
                     /locus_tag="ACOIAP_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGZ2637263.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(20197..20901)
                     /locus_tag="ACOIAP_000344"
     CDS             complement(20197..20901)
                     /locus_tag="ACOIAP_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGZ2637264.1"
                     /translation="MGSIKDNLSEIRSKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGNKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYDKK"
     gene            complement(20911..21546)
                     /locus_tag="ACOIAP_000345"
     CDS             complement(20911..21546)
                     /locus_tag="ACOIAP_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HGZ2637265.1"
                     /translation="MKKVKYTRLVILGIFIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGAIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYREQKIDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVINEQSQSV
                     KFVILEGITYENESSVFVDYYKNDLNGVTSVNLYDKIILRPNSINTNIRIK"
     gene            21926..22966
                     /locus_tag="ACOIAP_000346"
     CDS             21926..22966
                     /locus_tag="ACOIAP_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGZ2637266.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(23422..24777)
                     /locus_tag="ACOIAP_000347"
     CDS             complement(23422..24777)
                     /locus_tag="ACOIAP_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGZ2637267.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDESDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VREMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLNVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(24803..25072)
                     /locus_tag="ACOIAP_000348"
     CDS             complement(24803..25072)
                     /locus_tag="ACOIAP_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGZ2637268.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(25362..27323)
                     /locus_tag="ACOIAP_000349"
     CDS             complement(25362..27323)
                     /locus_tag="ACOIAP_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637269.1"
                     /translation="MKKYEIFIFISIVVLCFISFPYKVFGQEENCLEDFERWVQENKN
                     NKEKIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHVENGGSISIGINNIIATDGTALYVEEGGDLYIKSSYESVEKIKANGKDAI
                     GIYTENDIRIINKDIEVTGERAIGVYSKGDVEIEESSIKAYSNNNENELLRDNNKLVQ
                     SIISESKKVYIIDSYNELIPSIAEDSGYNIVKCCYRGIGVFSEEIKVSKDDKIENIKF
                     PQYMVLETSSGNQLDIDVEWDFTDYYEKLEKGEKFNITGKFKTETLNKEKIIINDDVV
                     PILNIYVMDKKPIDNLELEFQNTKKGYVAALFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRIRVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEQEND
                     DIDGDRGGGGRDDPDRDKDDNSQNGNNGNDNNDSNNNQNNNNENDNSDEKQPNAPKDD
                     VESSTGSNENKNPQGDIPKEGNIPKDGNKENNSDKEKGVFNKSSIIENDGDYDLNLKS
                     IFGINEHSFPYRESISNKNQDTNKNKSNISDYNGIINNNYKLESKEYNLKKDIIFLAC
                     ILTPIMIGSILIVNSDTRKSIIKFIKEKK"
     gene            complement(27506..28981)
                     /gene="spoIVA"
                     /locus_tag="ACOIAP_000350"
     CDS             complement(27506..28981)
                     /gene="spoIVA"
                     /locus_tag="ACOIAP_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HGZ2637270.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIMQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(29071..29247)
                     /locus_tag="ACOIAP_000351"
     CDS             complement(29071..29247)
                     /locus_tag="ACOIAP_000351"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637271.1"
                     /translation="MYIKFFNCICSGIDRTAQLHLDSNTRILQRGDIVIHSRQVWYEN
                     YRAENERISICKRN"
     gene            complement(29260..29442)
                     /locus_tag="ACOIAP_000352"
     CDS             complement(29260..29442)
                     /locus_tag="ACOIAP_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I V"
                     /protein_id="HGZ2637272.1"
                     /translation="MFCYINPKGTTVGIEKHIVSASFSEYMTDKSFVIKDVGSKIFEM
                     RYVKDVGDNALLKYVS"
     gene            29452..29724
                     /locus_tag="ACOIAP_000353"
     CDS             29452..29724
                     /locus_tag="ACOIAP_000353"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637273.1"
                     /translation="MFPEDLGVHDSDISLMITGESIKERNKILLNNLVDTGYIPAKDL
                     DIINDIIISFYQNLLFLKKNTGKNSDDDELTMKTISSIEYIIKHAK"
     gene            complement(29880..30899)
                     /locus_tag="ACOIAP_000354"
     CDS             complement(29880..30899)
                     /locus_tag="ACOIAP_000354"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGZ2637274.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIILAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTWLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(30930..31544)
                     /gene="plsY"
                     /locus_tag="ACOIAP_000355"
     CDS             complement(30930..31544)
                     /gene="plsY"
                     /locus_tag="ACOIAP_000355"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGZ2637275.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVVITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(31578..32903)
                     /gene="der"
                     /locus_tag="ACOIAP_000356"
     CDS             complement(31578..32903)
                     /gene="der"
                     /locus_tag="ACOIAP_000356"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGZ2637276.1"
                     /translation="MSISRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRI
                     FAEVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAA
                     DKEIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLD
                     EIVENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAID
                     TYFEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTE
                     QDTKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAK
                     TNQRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTD
                     IRPPKITLFINDKELTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(32931..34259)
                     /locus_tag="ACOIAP_000357"
     CDS             complement(32931..34259)
                     /locus_tag="ACOIAP_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HGZ2637277.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLEVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNGKSASKTIEQIHQMQQKYLKQLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEDILKRDKKVSIATG
                     HSAYEFIQSMANAMMDKFKNLQINVYEIKNKFFGETITVSGLLTAKDLKEQLENKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMKIKIIPCLNEGKDFVDKILK"
     gene            complement(34495..34695)
                     /locus_tag="ACOIAP_000358"
     CDS             complement(34495..34695)
                     /locus_tag="ACOIAP_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637278.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(34697..35629)
                     /locus_tag="ACOIAP_000359"
     CDS             complement(34697..35629)
                     /locus_tag="ACOIAP_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HGZ2637279.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLISQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLLLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(35675..36607)
                     /locus_tag="ACOIAP_000360"
     CDS             complement(35675..36607)
                     /locus_tag="ACOIAP_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HGZ2637280.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYDLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNDVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKRTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(36662..37951)
                     /locus_tag="ACOIAP_000361"
     CDS             complement(36662..37951)
                     /locus_tag="ACOIAP_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2637281.1"
                     /translation="MEDLNSVYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLKSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILRFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(37980..38672)
                     /locus_tag="ACOIAP_000362"
     CDS             complement(37980..38672)
                     /locus_tag="ACOIAP_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637282.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(38687..39445)
                     /gene="pgeF"
                     /locus_tag="ACOIAP_000363"
     CDS             complement(38687..39445)
                     /gene="pgeF"
                     /locus_tag="ACOIAP_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HGZ2637283.1"
                     /translation="MKDYINIKNVQDIKEYVNLSGNCKEIDEKLKSVNLVITCKNIDA
                     KNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPLL
                     LFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIGP
                     SIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLICSGVKKENI
                     INLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(39445..39906)
                     /gene="nrdR"
                     /locus_tag="ACOIAP_000364"
     CDS             complement(39445..39906)
                     /gene="nrdR"
                     /locus_tag="ACOIAP_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGZ2637284.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIEEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKDLDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(39928..40191)
                     /locus_tag="ACOIAP_000365"
     CDS             complement(39928..40191)
                     /locus_tag="ACOIAP_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HGZ2637285.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(40295..41068)
                     /gene="sigG"
                     /locus_tag="ACOIAP_000366"
     CDS             complement(40295..41068)
                     /gene="sigG"
                     /locus_tag="ACOIAP_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HGZ2637286.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(41160..41882)
                     /gene="sigE"
                     /locus_tag="ACOIAP_000367"
     CDS             complement(41160..41882)
                     /gene="sigE"
                     /locus_tag="ACOIAP_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HGZ2637287.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(41907..42752)
                     /locus_tag="ACOIAP_000368"
     CDS             complement(41907..42752)
                     /locus_tag="ACOIAP_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HGZ2637288.1"
                     /translation="MVYIEYYVIENLVINYIIISCTSILTKRYNPKKNKLLGASLGGA
                     YSVAYLYPSMNILFTIPFKIIIMSIITLISFRSKSKKDYVHVALVFYLVNIFISGSTY
                     FIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINIKLLEKSFCC
                     KALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQEIIGSLDDK
                     TSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDREYGAIMNPN
                     ILPGF"
     gene            complement(43078..44352)
                     /locus_tag="ACOIAP_000369"
     CDS             complement(43078..44352)
                     /locus_tag="ACOIAP_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HGZ2637289.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGGIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEVPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(44637..45794)
                     /gene="ftsZ"
                     /locus_tag="ACOIAP_000370"
     CDS             complement(44637..45794)
                     /gene="ftsZ"
                     /locus_tag="ACOIAP_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGZ2637290.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLETKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(45984..46337)
                     /locus_tag="ACOIAP_000371"
     CDS             complement(45984..46337)
                     /locus_tag="ACOIAP_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HGZ2637291.1"
                     /translation="MLWVLGGLAFGVVIGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGISLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(46436..47110)
                     /locus_tag="ACOIAP_000372"
     CDS             complement(46436..47110)
                     /locus_tag="ACOIAP_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HGZ2637292.1"
                     /translation="MKKKIVILGAFILGIFISTYIKSLDPNRVYITLGQTENIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSSVTGPG
                     ITITMKDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFTK"
     gene            complement(47115..47813)
                     /locus_tag="ACOIAP_000373"
     CDS             complement(47115..47813)
                     /locus_tag="ACOIAP_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HGZ2637293.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEISSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(47836..48576)
                     /locus_tag="ACOIAP_000374"
     CDS             complement(47836..48576)
                     /locus_tag="ACOIAP_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HGZ2637294.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNINLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSVDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(48837..50063)
                     /gene="murG"
                     /locus_tag="ACOIAP_000375"
     CDS             complement(48837..50063)
                     /gene="murG"
                     /locus_tag="ACOIAP_000375"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HGZ2637295.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDVVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEEKL
                     VFTGNPVRKEILLSRKNIARKNLSISEEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMESISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(50081..51211)
                     /gene="spoVE"
                     /locus_tag="ACOIAP_000376"
     CDS             complement(50081..51211)
                     /gene="spoVE"
                     /locus_tag="ACOIAP_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HGZ2637296.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIERNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGVALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(51263..52618)
                     /gene="murD"
                     /locus_tag="ACOIAP_000377"
     CDS             complement(51263..52618)
                     /gene="murD"
                     /locus_tag="ACOIAP_000377"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGZ2637297.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDIDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSNEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKTNIFMNQTSEDFCV
                     LNYDDEIVKGLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(52637..53605)
                     /gene="mraY"
                     /locus_tag="ACOIAP_000378"
     CDS             complement(52637..53605)
                     /gene="mraY"
                     /locus_tag="ACOIAP_000378"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGZ2637298.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIVTVVLAWISIIAVF"
     gene            complement(53648..55021)
                     /gene="murF"
                     /locus_tag="ACOIAP_000379"
     CDS             complement(53648..55021)
                     /gene="murF"
                     /locus_tag="ACOIAP_000379"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGZ2637299.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGNISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLSKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     ANTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDIYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(55188..57167)
                     /locus_tag="ACOIAP_000380"
     CDS             complement(55188..57167)
                     /locus_tag="ACOIAP_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HGZ2637300.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASKIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGIEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDVKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(57179..57526)
                     /locus_tag="ACOIAP_000381"
     CDS             complement(57179..57526)
                     /locus_tag="ACOIAP_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637301.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGTKCILLIATFAVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(58003..58938)
                     /gene="rsmH"
                     /locus_tag="ACOIAP_000382"
     CDS             complement(58003..58938)
                     /gene="rsmH"
                     /locus_tag="ACOIAP_000382"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGZ2637302.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAINTAKERLSEYEGRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKTIETTGELVDIIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKYLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEVEANPRSRSAKLRVAEKI"
     gene            complement(58968..59714)
                     /gene="lgt"
                     /locus_tag="ACOIAP_000383"
     CDS             complement(58968..59714)
                     /gene="lgt"
                     /locus_tag="ACOIAP_000383"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGZ2637303.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKESKRVGIKEDD
                     VLNIAIIAIPAGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGLIAHIYLSKKNKNNISEE"
     gene            complement(60113..61399)
                     /locus_tag="ACOIAP_000384"
     CDS             complement(60113..61399)
                     /locus_tag="ACOIAP_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGZ2637304.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPLGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPKSVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINDNFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKKIILDYIEKSKKEGLSKEEFDRTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(61414..62679)
                     /locus_tag="ACOIAP_000385"
     CDS             complement(61414..62679)
                     /locus_tag="ACOIAP_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGZ2637305.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSISEFGYEDEIDSITSKELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIIDIPRADFIKNVDEVKVVDEQMEITQGKLVMGYRANVDYADTDRYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSILFISSGIETKDYDKAVEL
                     IKEQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFAFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            62995..64092
                     /gene="ychF"
                     /locus_tag="ACOIAP_000386"
     CDS             62995..64092
                     /gene="ychF"
                     /locus_tag="ACOIAP_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGZ2637306.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQIFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            complement(64702..66981)
                     /locus_tag="ACOIAP_000387"
     CDS             complement(64702..66981)
                     /locus_tag="ACOIAP_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2637307.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEEYFEVDNILSILKKQAINSSFKRM
                     GVILPNGTAYTTDGYREDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSDINVYSV
                     PIYKNNDVKGVIFATHSTKLYEKILSVPTFNGKGYSYVARSNGDIVLNPSSKNANSTK
                     ENLFSYIGKSDSISKSSINNMKSNIKNFKSGSLSYSMSGRGYYLSYAPIGINDWYLFS
                     EVPKAAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRASIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTAVKRKYLKVYEIYAENLKEILIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGIFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPDFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRLIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSVKGKEIN"
     gene            complement(67250..68704)
                     /locus_tag="ACOIAP_000388"
     CDS             complement(67250..68704)
                     /locus_tag="ACOIAP_000388"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HGZ2637308.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTNADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAISEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            68799..69737
                     /locus_tag="ACOIAP_000389"
     CDS             68799..69737
                     /locus_tag="ACOIAP_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGZ2637309.1"
                     /translation="MKHCKKCSIIFYNITEERSSIKTMDNKIGYLNDNFKIFNIRDKK
                     NIQFEYHNHDFNKIIIFINGNVTYFVEGIPYKLKPWDILFISNNEIHKPVIDSNVFYE
                     RIAIWISPEFMKKNSDATSDLEKCFKISTENKCNRLRLNMHDIESIKSFIEQINISES
                     NTEFGNEILRNALFIQLMIFLNRIFLKNENIESTEDVFYDETIKKVLDYINSNIDDKL
                     SIDSISSEFFISKYYLMRKFKSHTGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCG
                     FNDYSSFVRAFKKNYGVSPKNYINSKNPLDITLLDE"
     gene            complement(69951..72023)
                     /gene="ptsG"
                     /locus_tag="ACOIAP_000390"
     CDS             complement(69951..72023)
                     /gene="ptsG"
                     /locus_tag="ACOIAP_000390"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005355 - glucose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1904659 - glucose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-specific PTS transporter subunit IIBC"
                     /protein_id="HGZ2637310.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMIDNSMYASIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAVMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDDSETNVEVIDMSKNELASEILVALGNKENLKSLDACITR
                     LRLIVNDINKVDKEKLKSLGAAGVMVIGNNVQVIFGPKSDSIKSDIKDIIEGKTKIES
                     AVIKNNDKNKMKKNMEVANMENALVENIYSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSNDGLIYSPVDGTIGVIFPTKHAIIIKSKKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGITTAKEENRVIIL
                     RDDIEKIG"
     gene            complement(72325..73167)
                     /gene="licT"
                     /locus_tag="ACOIAP_000391"
     CDS             complement(72325..73167)
                     /gene="licT"
                     /locus_tag="ACOIAP_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGZ2637311.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKNK
                     IERTFIIQDESFLDKIGKLASQVDEKFFAISTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENIIIKNELLHEIKRIHKKEYEIGKWAVDYINKEFGVKFPLDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     REKINDTSNEIIDIIKVKYEKDYNCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(73427..75469)
                     /locus_tag="ACOIAP_000392"
     CDS             complement(73427..75469)
                     /locus_tag="ACOIAP_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGZ2637312.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWNNIPLAIYQIVLGIILSILP
                     FKFLFSFNPEIFVICIIAPLLFSEAQNVSRKELLELRKPILLLAFGLVLTTVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFIITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFIYFVAEEVGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNEDMTLKLTFISALIVFILFVIRFIWVYLWH
                     DSFIKTKKNPLNNFFVGFLGFKDEEAVKENISRCKYSLIVATCGVHGTFTLATALSIP
                     FHLANKDVFPMRDTVLFISSEVILISLILATVLLPRLLKSNSQESEHLLSDKEAYKLI
                     LKEAILKLSNEKAQEAQLVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADKQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIIKLKISMWTIDRKVKKEVKEKIT
                     KIVSENKEIIKEFHYAYALSTKTAISFINKNTDENNRHEALISIRFYNRYLNWITRKI
                     QNDDKFESRVEYYRVMAIQSQRDSVQQLVENKQISREVAKELLENILYDEMMMIES"
     gene            complement(75620..76591)
                     /locus_tag="ACOIAP_000393"
     CDS             complement(75620..76591)
                     /locus_tag="ACOIAP_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637313.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFGKEIKFVKAVDGISFDLKKG
                     ETLAIVGESGCGKSSAGRTILRLIEKTEGKVEFNGIDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHDLVPKNEIKDNILNIVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKEELYLHSQHPYTKALMSAVPVQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEVPVLKEISRNHFVACHLI"
     gene            complement(76592..77569)
                     /locus_tag="ACOIAP_000394"
     CDS             complement(76592..77569)
                     /locus_tag="ACOIAP_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637314.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNGVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFQGKDILKMNENELMRIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMLHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVVVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPVLGKNKDKRLYSIPGQV
                     PNPIGIPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            77788..79347
                     /locus_tag="ACOIAP_000395"
     CDS             77788..79347
                     /locus_tag="ACOIAP_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2637315.1"
                     /translation="MKFKKLASLILVSALMLTFTACASNDKEKSNGGKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNED
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQNTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAKIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIEDAKPSPAI
                     LFEDWSKLYVE"
     gene            79453..80412
                     /locus_tag="ACOIAP_000396"
     CDS             79453..80412
                     /locus_tag="ACOIAP_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637316.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     AQDIENIRVNMGLDKPVYVRYLSWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKISSIFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVVTAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            80415..81227
                     /locus_tag="ACOIAP_000397"
     CDS             80415..81227
                     /locus_tag="ACOIAP_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637317.1"
                     /translation="MFTNILKELKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKISTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQKYIFDKLYLAVFPGLLIFLTVMSFTIISKKFSSNT"
     gene            complement(81442..82344)
                     /locus_tag="ACOIAP_000398"
     CDS             complement(81442..82344)
                     /locus_tag="ACOIAP_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HGZ2637318.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKIRIGIPPL
                     ILGIVFSDVVAQLVANNPDIEFDIVERGAYDLSRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNYPITWKVVLCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            82697..83875
                     /locus_tag="ACOIAP_000399"
     CDS             82697..83875
                     /locus_tag="ACOIAP_000399"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HGZ2637319.1"
                     /translation="MKDVVIVSAVRTPIGNFGGVFKNTSAVQLGTITVKESISRIGLN
                     LSEINEVIIGNVLQAGLGQNVARQIAINAGIPNSVPSYTINKLCGSGLKSVQLAAQSI
                     ASGENDVVIAGGTENMSQAPYIVPTARFGNKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAEKAIKNKRFKEEIIPVNILIRRGKMETIDTDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSKQKADELGIKPLVKI
                     KSYASAGVEPEIMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVKTGLATLCIGGGQGISMVVSR
                     "
     gene            83884..84540
                     /locus_tag="ACOIAP_000400"
     CDS             83884..84540
                     /locus_tag="ACOIAP_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HGZ2637320.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKTTIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            84540..85205
                     /locus_tag="ACOIAP_000401"
     CDS             84540..85205
                     /locus_tag="ACOIAP_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HGZ2637321.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDDVNV
                     ILQSENGFLGLGAAEDGNSNDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISSTEAPLILSDSLNGNI
                     SVV"
     gene            85310..86086
                     /locus_tag="ACOIAP_000402"
     CDS             85310..86086
                     /locus_tag="ACOIAP_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HGZ2637322.1"
                     /translation="MLKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNKT
                     TTELQQEGYDCMNVKCDVTKEEEINQAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            86148..87482
                     /locus_tag="ACOIAP_000403"
     CDS             86148..87482
                     /locus_tag="ACOIAP_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HGZ2637323.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVLLNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSVAGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLARELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            87983..88936
                     /locus_tag="ACOIAP_000404"
     CDS             87983..88936
                     /locus_tag="ACOIAP_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HGZ2637324.1"
                     /translation="MRKNIPTKLKTILALGVLTLTTASSAVNASALSLENNVNTSNKN
                     LVYSNTRYKFSAKPNCSIKPELKPDKDNSCKDKNHSDKNCNNTNKPDNNKPESNKPDD
                     NNNSGSTDKPDNNKPESNKPDDNNNSGSTDKPDNNKPESNKPDDNNNSDSTDKPDNNK
                     PESNKPNDNNNSDSTDKPNDNNNSGSTSENFSAYQKEVVDLVNIERSKAGLNPLTLDS
                     SISNVATKKSQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVV
                     NAWMNSEGHRKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(89340..92879)
                     /gene="nifJ"
                     /locus_tag="ACOIAP_000405"
     CDS             complement(89340..92879)
                     /gene="nifJ"
                     /locus_tag="ACOIAP_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HGZ2637325.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLVAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     SIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGVTMSHLRFGDSPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(93397..93966)
                     /gene="pduL"
                     /locus_tag="ACOIAP_000406"
     CDS             complement(93397..93966)
                     /gene="pduL"
                     /locus_tag="ACOIAP_000406"
                     /EC_number="2.3.1.222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HGZ2637326.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(94038..94646)
                     /locus_tag="ACOIAP_000407"
     CDS             complement(94038..94646)
                     /locus_tag="ACOIAP_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2637327.1"
                     /translation="MDSTDKKGLKSPEIMIINGSPRINKNCSFIANEVKAMLEEYGLS
                     CKIFNIYDMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYILNKPSIDRNKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNDTDNVSYMSNQEFKDIIYKNLKRYIDSI"
     gene            complement(94654..96417)
                     /locus_tag="ACOIAP_000408"
     CDS             complement(94654..96417)
                     /locus_tag="ACOIAP_000408"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing SpoIIE family protein
                     phosphatase"
                     /protein_id="HGZ2637328.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYLTEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDTFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYAIKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDASYE
                     NNTISMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(96460..96921)
                     /locus_tag="ACOIAP_000409"
     CDS             complement(96460..96921)
                     /locus_tag="ACOIAP_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637329.1"
                     /translation="MLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKIDS
                     IFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKNNI
                     DISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            97110..97571
                     /locus_tag="ACOIAP_000410"
     CDS             97110..97571
                     /locus_tag="ACOIAP_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637330.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILDEKIVNETNFKISYRNYIETLINIQNENLSNFKKKSTKTAKCFNISQIT
                     QLKNLLNNTGYNLLIPYKYLTSRDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            complement(97664..97834)
                     /locus_tag="ACOIAP_000411"
     CDS             complement(97664..97834)
                     /locus_tag="ACOIAP_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637331.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(98023..98244)
                     /locus_tag="ACOIAP_000412"
     CDS             complement(98023..98244)
                     /locus_tag="ACOIAP_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HGZ2637332.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(98328..99554)
                     /locus_tag="ACOIAP_000413"
     CDS             complement(98328..99554)
                     /locus_tag="ACOIAP_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGZ2637333.1"
                     /translation="MKKVVIIGGGPAGMIAASTACERGCDVTLVEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNEDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNNKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIMDTKPSLIGIEVQESFTRDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTIILDLKPALDEEKL
                     DKRIQKDFQKYTNKKFEKALDDLLPKKLIPVIVNLSEINPDTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIDEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            complement(99615..100547)
                     /locus_tag="ACOIAP_000414"
     CDS             complement(99615..100547)
                     /locus_tag="ACOIAP_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGZ2637334.1"
                     /translation="MDIQLSILLFFQNLRNPILNFIFLVLTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYIHVIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVIF
                     IKIFDYIDDNKNYILLLVLLIPFIIVAIFLNSSEYFEKFGIIVGFVFGYIVEDRFVKF
                     NTDNNNKKINFSSKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSINFMNFIKNTVVVFYGVAGAPALFKVLKLN"
     gene            complement(100636..101163)
                     /gene="hpt"
                     /locus_tag="ACOIAP_000415"
     CDS             complement(100636..101163)
                     /gene="hpt"
                     /locus_tag="ACOIAP_000415"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGZ2637335.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            101392..102468
                     /locus_tag="ACOIAP_000416"
     CDS             101392..102468
                     /locus_tag="ACOIAP_000416"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HGZ2637336.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSMDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSMDKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTNTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNIDLWNINIIASKMGEIMFSDLDFISNTISLVSAERNY
                     LLKELKNIKNLNVYDTKGNFILCKIKTKELTAKSLREKLIPQKIIIRDCCSFEGLNEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(102576..103784)
                     /locus_tag="ACOIAP_000417"
     CDS             complement(102576..103784)
                     /locus_tag="ACOIAP_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HGZ2637337.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFVVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGSKEKQSA"
     gene            104216..104365
                     /locus_tag="ACOIAP_000418"
     CDS             104216..104365
                     /locus_tag="ACOIAP_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637338.1"
                     /translation="MTKTMICDYCNKVINNNSEYITFHKKNYVKTSVCINCVLKLMDK
                     TKENK"
     gene            complement(104687..104866)
                     /locus_tag="ACOIAP_000419"
     CDS             complement(104687..104866)
                     /locus_tag="ACOIAP_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2637339.1"
                     /translation="MRLKGKVTVLILACLVSIGVVGCGDKENNDTTKNKAEKSITDGQ
                     ENSTDTAPDVTSDSK"
     gene            105278..105595
                     /locus_tag="ACOIAP_000420"
     CDS             105278..105595
                     /locus_tag="ACOIAP_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637340.1"
                     /translation="MNFGNINLIIIGVGIIILTTIISLIKPKISFCSEKYFNKLESIY
                     GNIDRKRTVKLEVLSRYVMGLEYIVIGLFTRRLDITIIAMIIVAVITTVLYYLIRKKY
                     ITI"
BASE COUNT        34942 a        17918 c        12142 g        40683 t
ORIGIN      
        1 aatatacctt aattctaact atccttaatt ttatttatct cctagtgtta ttttacgtat
       61 ttttctataa aatactttta gttttttact tttgaatttt ttataggagg gtatttagtg
      121 gatatattaa tttttgataa tgatgtttgt tttggaataa aactaaaaga aaagataaat
      181 aatattttaa taaaagaagg ttttgataac gatgttgtaa gattatatta taatgcaaat
      241 ttgttattaa aagagcttac tgaaaaaaat aaagtaagaa tatattttat agttgtagac
      301 gcaaaatata agataagtaa tgaattatgt gatggattat ggatagcaca aaaaattaga
      361 gaatcagatt atattagtcc aatcatattt cttacaaatc atatagaaat gattttaggg
      421 atcttcgatt ataggttata agttatggac tttatactaa aacatgatat ggaaattgct
      481 gaaagtaaga taaaagcttg tattaaaatt gctcataaaa gatacattaa agaaaaaaat
      541 tatcgctcta atttttttac tatctactca gattcctcac tatggaaaat ttcatttgat
      601 gaagttatat attttgaaac aagcactatt ccacataaaa taaaattagt gactacttct
      661 agaatatttg aattctataa aagtttaaag tctttatcag atttagatgc atgctttgtt
      721 cgtgtacata aatcttttgt agttaataaa tatcatattg tttctatcga cctaaagaaa
      781 aataatgtta aaatgagtaa cggccatata tgtcgtatat ctaatacata tagaaatatt
      841 ttaaagaaca ttattaaaag ataataaata gaaaaagggg atgtctcaag ataaaaattt
      901 gaaccatctc tttttttata caaaaaaagt agttcctaag aatcctctat atgataatcg
      961 ttttgtgaaa aaacacatac tgactatatc atatacaatt gctattagac attgtaacaa
     1021 ttgttcctag attatgattc aacaagatag ctcattaaat cataaaggta tgaaatagtc
     1081 tctttaaaac attcagttgt tattttgtac tgacatatca tataaataca tatttttatg
     1141 atatatagct acatatttta tgaaatttat ataaaaaatt cttatttaga ttatataatc
     1201 taaataaatt aaaattcaaa agttaattaa actaatattg ggagggagaa taaatgaaaa
     1261 aatttagaaa acataaaagt attagtaatt gtatatctat attgttgata ttatatctaa
     1321 ctttaggtag tttgttacct aataacattt atgcacaaga cttacaaagc tatagtgaaa
     1381 aagtttgcaa tactacttac aaggctccta tagaaagacc agaagatttt cttaaagata
     1441 aagaaagggc taaagaatgg gaaagaaaag aagcagaaag aatagagcaa aaacttgaaa
     1501 gatctgaaaa agaagcatta gaatcatata aaaaagattc tgtagaaata aataaatatt
     1561 ctcagacaag aaattatttt tatgattatc aaatagaagc aaattctcga gaaaaagaat
     1621 atagagaact tcgaaatgct atatcaaaaa ataaaataga taaacctatg tatgtctatt
     1681 attttgaatc tccagaaaaa tttgcattta ataaagtaat aagaacagaa aatcaaaacg
     1741 aaatttcatt agaaaaattt aatgagttta aagaaactat acaaaacaaa ttatttaagc
     1801 aagatggatt taaagaaatt tctttatatg aacctggaaa aggtgatgaa gaacctacac
     1861 cattacttat gcacttaaaa ttacctagaa atactggtat gttaccatat acaaatacta
     1921 acaatgtaag tacattaata gagcaaggat atagtataaa aatagataaa attgttcgta
     1981 tagttataga tgggaaacat tatattaaag cagaagcatc tgttgtaagt agtcttgatt
     2041 ttaaggatga tgtaagtaag ggggactctt ggggtaaagc aaattataat gattggagta
     2101 ataaattaac acctaatgaa cttgctgatg taaatgatta tatgcgtgga ggatatactg
     2161 caattaataa ttatttaata tcaaatggtc cagtaaataa ccctaaccca gaattagatt
     2221 ctaaaatcac aaacattgaa aatgcattaa aacgtgaacc tattccaact aatttaactg
     2281 tatatagaag atctggtcct caagaatttg gtttaaccct tacttcccct gaatatgatt
     2341 ttaacaaacc agaaaatata gatgctttta aatcaaaatg ggaaggacaa acactgtctt
     2401 atccaaactt tattagtact agtattggta gtgtgaatat gagtgcattt gctaaaagaa
     2461 aaatagtact acgtataact atacctaaag gttctcctgg agcctatcta tcagctattc
     2521 caggttatgc aggtgaatat gaagtacttt taaatcatgg aagcaaattt aaaatcagta
     2581 aaattgattc ttacaaagat ggcgctataa caaaattaat tgttgatgca acattgatac
     2641 cttaatattt tttcacataa ataatttaat atatttcaaa ttaaaggagg agaaataatg
     2701 aaagtacaaa tgaggaataa aaaggtatta agttttttaa cacttacagc catagttagt
     2761 caagcattag catatcctgt atatgctcaa actagtacaa gtagccattc tgataataaa
     2821 aaagaaatta taaatgaaga catactcaca aacaacggat taatgggata ttatttcaca
     2881 gacgaacact ttaaagattt aaaattaatg gcacccataa aagatggtaa tttaaaattt
     2941 gaagaaaaga aagtagataa acttctaaat aaagacaaat caaatgtaaa atctatacga
     3001 tggacaggaa gaataattcc ttctaaggat ggtgaatata cattatcaac tgatagagat
     3061 gatattttaa tgcaagtaaa taatgagagt actatatcaa atacacttaa agttaatatg
     3121 aaaaagggta aagaatataa atttagaata gagctacaag ataaaaattt aggttcaata
     3181 gataatttgt catcacctaa tctttattgg gaattagatg gtattaagaa aattatacca
     3241 gcagaaaatt tattcttaag agattattct aatatagaaa aaaatgatcc atttatccca
     3301 aataacaatt tctttgaccc aaggttgatg tctgattggg aagacgaaga tttggataca
     3361 gataatgata atataccaga ttcatatgaa cgaaatggat atactattaa ggacttaatt
     3421 gcagttaagt gggaagatag ctttgcagaa caaggctata agaaatatgt atcaaattat
     3481 ttagagtcaa atactgctgg agatccatat acagattatg aaaaagcttc aggttctttt
     3541 gacaaggcta taaagaccga agcaagagat ccgttagttg cagcgtatcc aattgttgga
     3601 gtaggtatgg aaaaattaat tatatctaca aatgaacatg cctctactga tcaaggtaaa
     3661 actgtttcca gagctactac taacagtaaa actgaatcta atacagctgg tgtttctgtt
     3721 aatgtaggat atcaaaatgg attcacagct aatgtaacta caaattattc ccatacaaca
     3781 gataattcaa ctgccgttca agatagtaat ggagaatcat ggaatactgg attaagtata
     3841 aacaaaggag aatctgcata tataaatgca aatgttagat attacaacac aggtactgca
     3901 cctatgtaca aagtgacacc aacaacaaat ttagtgttag atggagatac attatcaact
     3961 atcaaagcac aagaaaatca aattggcaat aatctatctc ctggagatac ttatcccaaa
     4021 aaagggcttt cacctctggc tcttaacaca atggatcaat ttagctctag actgattcct
     4081 ataaattatg atcaattaaa aaaattagat gctggaaagc aaattaaatt agaaacaaca
     4141 caagtaagtg gaaattttgg tacaaaaaat agttctggac aaatagtaac agaaggaaat
     4201 agttggtcag actatataag tcaaattgac agtatttctg catctattat attagataca
     4261 gagaatgaat cttacgaaag aagagttact gctaaaaatt tacagaatcc agaagataaa
     4321 acacctgaac ttacaattgg agaagcaatt gaaaaagctt ttggcgctac taaaaaagat
     4381 ggtttgttat attttaatga tataccaata gatgaaagtt gtgttgaact catatttgat
     4441 gataatacag ccaataagat taaagatagt ttaaaaactt tgtctgataa aaagatatat
     4501 aatgttaaac ttgaaagagg aatgaatata cttataaaaa caccaactta ctttactaat
     4561 tttgatgatt acaataatta ccctagtaca tggagtaatg tcaatactac gaatcaagat
     4621 ggtttacaag gctcagcaaa taaattaaat ggtgagacaa agattaaaat acctatgtct
     4681 aagctaaaac cttataaacg ttatgttttt agtggatatt caaaggatcc tttaacatct
     4741 aattcaataa ttgtaaagat aaaagcaaaa gaagaaaaaa cggattattt ggtaccagaa
     4801 caaggatata caaagtttag ttatgaattt gaaactactg aaaaagattc ttctaatata
     4861 gagataacat taattggtag tggtacaaca tacttagata acttatctat tacagaactg
     4921 aatagtactc ctgaaatact taatgaacca gaagttaaaa ttccaactga ccaagaaata
     4981 atagatgcac ataaaatata ttctgcagat ttaaatttta atccaagtac aggaaatgct
     5041 tatataaatg gtatgtattt tacaccaaca caaactaata aagaagctct cgattatatc
     5101 caaaaatata gagttgaagc tactttacaa tattctggat ttaaagatat tggaactaaa
     5161 gataaagaaa tgcgtaatta tttaggagat ccaaatcaac ctaaaactaa ttatgtcaat
     5221 cttaggagtt attttacagg tggagaaaat attatgacat acaagaaatt aagaatatat
     5281 gcaattactc cagatgatag agagttatta gttcttagtg ttgattagta tcaaatgatt
     5341 taaatttgtc cccacaatac aatatatatt taccttataa agtactaaaa aattaacttt
     5401 ataaggtatt ttttatttaa atattctctt cttctaatat attctttttt agaactatat
     5461 tgtattataa agataattat ctatatcata tcatccatat ataaacataa attcatttaa
     5521 ttatataaat tttaaaaaat tttttttgat atattattga caattttcat tataagagtt
     5581 aaaattaact cataaattac atattgggta taaaatacaa tgtatgttag aagttgtttc
     5641 agaaggctat ggttttctga tttttttatg ctcagtagtg atatgcaaaa aagacaaagt
     5701 tgacatcagt taacttttac ctttattcta ctttccccaa agtaagaata atctaacccc
     5761 tttgagatga gcaaaagctc atcttttttt attatcaaaa ggtactgtct caaaatagaa
     5821 ataatcctct ttttcattgt tgaaatgatt aaaatatatt ttatttcata caaaaaagag
     5881 tgcctcatga acaaaagttt actttgagac tctctctttc atatcatata cttttttaat
     5941 aactttaaaa tttatttatc aagtaaggat agctaataat tagtatcttc tctctataaa
     6001 tcccactttt ttataaactt ttctaagagt ttttctagct tgtttttcag ctttttctgc
     6061 tcccatacta tatatttttt ctaaataatc tttattatta agaaggtcaa catatttttc
     6121 tcttataggt cttaaagctt ctgatactac ttcagccaca tcttctttaa atatgccata
     6181 accctttcct tcatacatgt ttacaatctc ttctacactc tttttactta aattagaata
     6241 tatatcaatt agatttttaa taccaggttg ttcatcattg tattttacaa cacctaaaga
     6301 atcagtaaca cttcttttta tctttctctt tatagagtct gaatcatctg ctaataatat
     6361 aaatgcattt tcatttgaat cagatttact cattttttta gttggctctt gcaaactcat
     6421 cactcttgct ccaccttttg ggtagtatcc ttctggaact acaaaagtag gtgaaaatct
     6481 attattaaac ctatttgcta aatcacgagc taactctaaa tgttgctttt ggtcatcccc
     6541 aactggaact aggtcagttt gatacaacaa tatgtcagca gccataagca ctggatatgt
     6601 gaataaacct gcatttagat ttgcttcact cttttgtgat ttatccttga attgagtcat
     6661 tctacttaat tcacccatat aagtcatagt atttaatacc cacataagtt caacatgctc
     6721 tttgacatgt gattgtataa atatagtatt tttttctgga tctaatccac aagctatata
     6781 ttgagcaagc aactctatag cattagctct taaaacttta gggtcctgag gtactgttat
     6841 tgcatgcaaa tcaactatac tataatagca atcataatta tcttgaagtt cagtccagtt
     6901 ttttatagct cctaaataat ttcctaaagt cattttgcct gatggctgtg ctccactaaa
     6961 tataactttt ttttcactca tttttttgta cctccttata tatttatatt gattttaaca
     7021 tatttaaaac tatgtcttta gaattattag cagcatcatg tacaaataca tcataagtaa
     7081 catcagcact tccatctgcc ttatcagaca ttgctcttat tattacgaat ggagtattat
     7141 ttaaatagca tacatgagct atagctccac cttccatttc tccacaatat ccaccaaaat
     7201 catttacgag ttcttctttt aattctttag aatttataaa tttatctcct gtaactactc
     7261 ttccttttaa tactttatga gtctttactt cttccacaga agatttgtaa gcagcatcta
     7321 taagtctttc atctgcttta aatacagaag tcttcattct tggtataact cccttagggt
     7381 ctccaaatgc tgtagtgtct acatcatact gtatagcatc agttgatatt actatatcat
     7441 taacatcaag tttttcattt aaagctcctg caacacctgt attaacaata gcatcaacct
     7501 taaattcgct tattagtatc tgggcacaaa gagcagaatt aaccttacct ataccacact
     7561 ttactaatac tacattctta ccttccaaaa ttcccttata aaattctaag ctagcttttt
     7621 ttatagtctc tctaatatcc attaaatcaa ctaaaatact aacttcttca tccattgcac
     7681 ctataattcc tattacgttc atttttcctc ctaaattttc tatattaaaa aatccgtcct
     7741 aaatcaatag gacggatata ttttccgtgg taccacctaa atttatatac actcaaaatt
     7801 gaatatatat atcttaatat atgctataac gtgcatacac gatatcaaat actctgtaat
     7861 cttaaattac atttcatttt actcctcaaa gacccattca ataaatactt tttattaagt
     7921 tctcagcatc cttaattctc tgtgcaaaaa tatatttatt tactatttct tatctcagga
     7981 tttaatttat taatttcttt attttataat attccttaca ctataaattg tcaactatat
     8041 attataatat ccaaaagaaa tttttaaaat acattttatt tagctgtttt cttttcatat
     8101 ctattccata accatagacc agataatata actagaagac ctccaccaat catctctatc
     8161 tcatatataa cattttcagc aaatgtaggc ataactggtg ctgcagataa taatatacca
     8221 actacagtta caactaaaac catttttgct aaacctaggc aagtacttgt tgattttgcc
     8281 atagtataag gtctaatttc atctggtctc tcttttctta gtttaatata agaagcatat
     8341 aataatacat atgggaataa tgcagttaat gctgtcatag ttacaagaac attgtatata
     8401 gcatcaacag aaggcattaa tgtagtcacc aatagtatta tagtaactat tattgcttga
     8461 agtataactg ctttagaagg tatcttgtgt tcatttacct ctaccaaact atctggaaat
     8521 attccttttt taacactacc aaataacatt tttattggtg acgctatgta aagaactatt
     8581 gctcctaata ctgaaaaagc tataccaaaa gctattaatt gaaccaacca agaaccaatt
     8641 cctaaagacg cacaaacagc agaaagtgca tctaatacac ctttagaagc agtaatttgg
     8701 tctggtggta ttatcattgt tattgcaatt gaacctaata catataatga agctactatt
     8761 ccagctgata ttaatattgc cttagggaag ttcttttcag gtttatctat ttctgttatg
     8821 aagttagcag cagtctctgc tcctgctaaa ccaaacatta tagctgatat agcaacaaag
     8881 gcatccatat taatttttgg agtcattgaa gctattgtgt atgtagaagc tatatcatgt
     8941 tttttcaata caaatactgc tacaaatgaa aatattataa gtatagcact tggtattgtt
     9001 gaacctaatg cacctgtatt agtaaatatt tttgtaaaac ttattccttt agttgctata
     9061 agagataatg cccagaatat tattaaagat aatataagta caaacatctt gttatcagca
     9121 agagctggat ttcctattgt ataagaaaca tttactgcta agaaagttaa aaatgaagaa
     9181 taccaaaata ttttagctgt ccagtttaac caagaaacta aaaatccata cttttctcca
     9241 aaggcttctt taacccaatc gtaaagacct ccatcacctt tttgatatgt agaagctaat
     9301 tcagcacaaa ttaaagctcc tggtacaaag tatataaatg agaataataa ccacataggt
     9361 attgcaccta atcctaaacc aaagcttgat gctgtagact tagctatcca tcttatacca
     9421 tacaaagctg atacattcat aaataccaaa ctccataggc ctattttttt cttttccatc
     9481 ctaatttaat ttctcctctc cattaattgt tttaaattta atttcaaaac taataaaata
     9541 gattcattat tattaaactg atatttttca aaatattttc atgttcaaaa acaattttaa
     9601 taataaattt taaatacttt gaaatcaaat cttattaaaa atgataaatt taaaagtttt
     9661 accactttaa gtctaatgat actaaatttt ttaaattgtt tcaatattat tttattataa
     9721 aattttattt attatttttc atggttatat aaaaagctaa aatacataac tttatagact
     9781 taatttatta cttttataga attttcacaa taaaaagtca ttttacttct gtatttaatg
     9841 caaaaacaga gattaaactt aatataaaaa atatataaca aaattttttt atatttctaa
     9901 aagaaaagta tactcttttt tgtttaataa tgctaaaatt gatttgtatt gaattttgat
     9961 taggaggaaa ttattatgaa aactcaaaga ttaaatgctg tacttgaaca aatgaaaaaa
    10021 gatgatattt ctcaaatgtt agtaagtgac cctacttcga tattttatct tacaggggta
    10081 ctaatccatc caggtgaaag attactagca ttatacttaa atttaaatgg caataataaa
    10141 ttatttataa atgaattatt cccagtttca gaagatttag gtgttgaaat ggtttggttt
    10201 aatgatactc aaaatccagt agaaataata actgaacata tagacaaaaa tgctactatg
    10261 ggtgttgata aaaactggcc agctagattc ttattaaact taatagaatt aggtggagga
    10321 agtaagtttg taaattcatc ttatataata gatactttaa gaatgtgtaa agatgaagaa
    10381 gaaaaagagt taatgagaat agcttcaaaa ttaaatgaca aggctatgga acaacttaaa
    10441 gctactgttt ctggtgaact tacagagaaa caacttgttg gtaaattatc taaaatatat
    10501 gaagacctag gtactgatgg attttcattt gaccctatta taggttttgg tcctaatgga
    10561 gctaatccac atggtgaacc tggaaatgca cttgtgaaac caggagatgc aataatatta
    10621 gatataggtt gtataaaaga taactattgt gctgatatga caagaactgt attctataaa
    10681 gaaatacctg aaaaaggtag agaaatattt gaaatagttc ttgaagctaa taagagagct
    10741 gaagccattg taaaaccagg agttagattc tgtgatatag atgcagctgc tcgtgattac
    10801 ataactgaaa agggatatgg acaatacttt actcatagaa ctggtcactc tatagggctt
    10861 gaagttcatg ataaaggaga tgtatcttct ataaatacag atactgtaca accaggaatg
    10921 atattctcta tagaaccagg tatatattta ccaggtgagt ttggagttag aatagaagat
    10981 ttagtacttg ttactgaaga tggttgtgag atattaaaca aacacgacaa agaaatatgt
    11041 gtagttggtt aattctaaaa tcaatttgat aaaattaaaa aaccatataa aaatgtttaa
    11101 aacattttta tatggtttta atttctcaat ctatgattta tttcaatcca tcatttatat
    11161 tgcagttatt aatattgcac cttttgaagt atatgtaccc atcactgaac caacttcaca
    11221 tattacaaca tctttatatt ttacatcctt ttccataact tcccttacct tttgagcctt
    11281 ttcagggcaa ttagcatgtc ctataaataa aaccttttct tctttatctt taatttttga
    11341 ctctactaaa gtaatcagct ttttcaaact atttccttcg cctcttgcct tatctatagg
    11401 agttacaacg ccatctgcaa cttgtattat cgccttaaaa ttcaaggtat ttataatttt
    11461 tcctgctatt ggatttatcc taccaccctt aatagcattt tctaaagttt caagagttcc
    11521 aaaaaatgga ggattatctt tatatttatt tattattgaa acaatctctt caatttcttt
    11581 tccttcttct attaatattg ccgcttttaa cactaattgt cctattccaa ttgacccact
    11641 aagtgaatct atgacctcaa ttttcttgtt atttccttct ttttcaaaca tatcttttgc
    11701 taaaagtgca ctattataag tcccagataa tcctgaactt atattaatta ccaatacact
    11761 ttcttcctga caatggtatg cttctaaaaa tttatctgga gaaggacatg atgtttttgg
    11821 tagtactttg ctctcactca tttttctata gaatgtttta ttatctattt cctttccaga
    11881 tatataactt tcttctccaa aagatacatt taaaccaaca acttctatgt tgtatttttc
    11941 tattatatca tctggtaagt cacatgcact gtccactatc aattttattt tatccatatt
    12001 aacctcacta taagatatta ttttatttat tcagtcggtc gtacgaccga tttaattatt
    12061 attttatata ttgaatgaaa aaaagtcaat agatatagat tctcccttta ttgacaataa
    12121 atattcataa gcttataatg ttattaattt gttataagta tacatggaga ggtaggtttt
    12181 atgaaaacaa ataatatgaa acaggctatt ttatcatctg caactaattt aatagccaaa
    12241 aatggagttc aaaatactag ccttgctgat attgcaaaag atgtaaatat aagtaaaggc
    12301 actttgtatt atcactacgc atctaaaaat gatattatat atgatattgc ggatactcat
    12361 ttagaagtta taactagtgc tatactaaac tgtgtaaaaa atgtcaaatc aaaaaattct
    12421 caaatagata tggttaactt aatcttagag aaaatctcta ctatagaaag tcgtggtagg
    12481 gtacatatgt atcttatttg tgaggcaatt acttcaaata atgatttaaa agaaagaatg
    12541 agattaaaat atattgaatg gagaactact cttaaatctg aaattgttga atcactagaa
    12601 aaatataata gtagcgaaaa tgaacaggat gctgaatcat tttctttttt actcatgtca
    12661 atagttgatg gtttagttgt ccaaagttta ttaaaaacag aaaaaatacc ttatgaaaat
    12721 atagcttctt ttttaattaa tcattggatt taaatttaat acttagataa ttaataaaag
    12781 tgaactattt aagttatcta ctctaacagt tcactttctt atttattatc aataaatttt
    12841 acttaaaacc ttcaattttt atttaaacct tcatggaatc acaaaataaa aatctcttat
    12901 aaatttaaaa tgtttttatt tatgttcatg tgtatgctca tctgaatgtt catgaccatg
    12961 tgtatgtgta tgttcatggc tatgctcatg agtacctgaa aaaccatcat catgattatg
    13021 gtcgtgacct acaccattta tatgctcatg ttcatgacca tgactgtgag aatgttgatg
    13081 tgaatgttca ttgttatctc ctccacagca tccttttcct ccagtcccac aacattcact
    13141 tgtatgtgga ttatgatgat ttcttactac aaatctctct cttaacataa ttcttatacc
    13201 tcctagtata ttattgagta cttcatgtac tccattaatt acagtataca tctaactagg
    13261 tataatctca atacatatgg tattttttaa catctatagt attaaagaaa cttatcctta
    13321 aaacctccac cttttacttc ttcaacatta ttgacagaaa taaaagcttc actatccata
    13381 tcataaatta aatctttaaa tttacctatt tcatttgcag atattatgca ataaatcatc
    13441 tttttcttat tctgtgtata tgcaccttct gcctctaaaa aagtgactcc tcttcccatt
    13501 ttattcatta ttactttaga tatttcatca tatttatttg aaattaaaag tatggatttt
    13561 tttctatcaa agcaatcttt tcctatatcc atagtaaaag aaattatata cattgtaatt
    13621 aaagtgtaca tcaccaattt agctccaaat aagaaagccc ctgcacatac tacaaaaaaa
    13681 ttaataaata aaaatgtatt tttcataggt atatcatact ttcttttcat tatagctgct
    13741 actatatcaa gtcctccagc agtagctctt gctttaaaag tcaatcccat gcctatacca
    13801 gttaatgcac caccataaat acactgtagc atagtatcat ctatcgggaa atatttagca
    13861 atatcttgtg ttaacccaag tgctaaagaa aatagtaaca tattgacaaa acttatcaat
    13921 aaaaacttat tatcaaaata ctttctagct ataataaata ttggtatgtt catcaagaaa
    13981 cttgatattc cctgatttat gccaaacaat ttatataata taacacaaat tccagctact
    14041 cctccactta ataatttggc tggtgctaga tataaattta ttcctaaggt tgatagaatc
    14101 atacccaata taataagaca atattgtaaa aatatgttat tatcaatact tagttttttg
    14161 ctttcaccat acatcaaaac gcaccccttt gcataataaa taaactaccc tgcaaaacac
    14221 acgataaatt tataaataaa tttatcagaa gtagcttact aaaaatatta ttcatcctca
    14281 cttaaacgtt tattcattaa tattctatca catgatatga ataatttata tgatttatat
    14341 agaattattt attgtaaatt ttggaatatt aaaacatttt agtgaataga taattatatt
    14401 acacaaaaaa tccctataga aatctataaa ctaatttcta tagggatttt gattaactaa
    14461 ctattttttt acaactttta tacctgtcat atggtcgttt aagttttgtt cttctaaaga
    14521 tttatcatct actctgttta tttctaaagc taaagtttca gacttgatgt attcattaaa
    14581 atggtcaaca gccttagcaa tttcgtcatc accacagtat tctattacta tattatctaa
    14641 tacttcaaag ttattagatt ttctcaattg ctgtacttta gatataaatt ctctagcata
    14701 accttcatta atcaactctt cagttagctt agtatctagt ataacaaaaa gattgttttc
    14761 aacagataca ttaaatcctt ccttagcagt tatacctatt aatactaaat ccttattaaa
    14821 ttcaaaagct tcaccatcta aatcaactgt tagagtctca cctttttcaa gtttattagc
    14881 agtttcatga gcatttaatt tacttaaagc tccaacgaat aaattcatct tagaacctaa
    14941 taatggtcct gcttccttaa agtttggttt taaactaaag ttcatatact catctaaatc
    15001 cttagcaaag attacctctt taacattaag ctcttctttt attaaatcaa ctacatcgct
    15061 tattgtatct tcaaacttac catctactaa aactttttgt aatggttgac gaacttttat
    15121 tctttcaact tctcttgaag ctctacctaa agtaactaag tttttagcta aatccatttt
    15181 ttcttctaat ttagtatcca ctaactcttc attacactta ggatattcag ctaaatgaac
    15241 agatacttct cctgttaagt ttctatacat ttcctctgac atatatggtg caaatggagc
    15301 tatagctcta caaagaccat gtaacaattc ataagttgtg ttgtacactg ctttcttatc
    15361 ttctgttaat tcagttgccc agaatcttct tcttgaacgt cttatatacc agttagataa
    15421 atcatcattt ataaaatctt gtatcattct taaagtttta tttaactcaa atatagctaa
    15481 attttcttct acatctttca ttaaattatt gaatttagat aatatccatc tatcaagttc
    15541 tggtctatct ttatattcta caaaaaattc agttggattt atatcatctg tatttgcata
    15601 taaagtaaag aaattatata cattcttcat agtacctata aatttacttt ggatttcttt
    15661 taatccatcc atatcaaatt tagttggagt ccatggtgga gaaacatata gtaaatacca
    15721 tcttaatgca tctgctccat attggtcaaa taattccatt ggatttactg tgtttcctct
    15781 tgatttactc attttcttac catctttatc aagtacaagg tctggaacta aaacactctt
    15841 atatggtgct ttccctaata caaatgttga tactgcaagt aatgagtaga accatcctct
    15901 agtctggtct ataccttctg atatataatc agctgggaat agttggtcaa agttttcctt
    15961 attttcaaat ggatagtggt gttgagcaaa tggcatagcc ccactatcaa accaacagtc
    16021 tataacttct gttactcttg tcattggttt tccacatttt tcacatttta agtgtatatc
    16081 atctacatat ggtctatgaa gttcaactgt ttctggattt acatcttcta tagctctttc
    16141 agctaattca gctcttgaac caactgaatc tgtatgacca cattcacatc tccatatagg
    16201 aagtggagtt ccccaatatc tagttcttga tattgcccag tcatttagat tttctagcca
    16261 gtttccaaat ctcttctctc ctacaaaact tgggaaccat tttacaccat tattattttc
    16321 tattaatttg tctttaagtt tagtcatctc tatataccag cttggttttg catagtatac
    16381 taatggagtt tgacatctcc agcagtgtgg ataattatga actacttttt ctttgctata
    16441 taatttattt tcagaagcta gccattttat tatttcaaca tctagcccat cttccattac
    16501 aaatctacct tcccaaggag tagatgtaaa tttaccagtt tcatctactg gttgaataac
    16561 tggtaaatca tatcttttac ctgtgttgta gtcatcttca ccaaatgctg gtgctgtatg
    16621 aactatacca gtaccatctt cagtagttac ataatctcct actgtaataa aaaatgcttt
    16681 tttgtcaact tctacaaaag gcattaattg ttcatattcc aaaccttcta ggtctttacc
    16741 tttcatttct tctaaaactt cataatcctc acctagtact ttatcagcta aaggtttaga
    16801 tacataatat atctcatcac cttttttaac ttttaaataa tctacatcag catttactgt
    16861 taacgaaaca tttgatggta aagtccatgg agttgttgtc catgctaaga aatattcatc
    16921 agcatctttt ttcttaaatt tagctataac tgtattagtt tttacttctt tatatccttg
    16981 tgcaacctca tgactagcaa gaccagttcc acatcttgga caataaggaa gtattttgtg
    17041 accttcatag atatatcctt ctttgttgaa tttattcagt atccaccata cagactctat
    17101 atagttatta tctaaagtta tatatggatt gtctaaatca acttcataag ccattctctc
    17161 agtcattatt ctccattgtt tttcaaatga gaaaactgat tctctacatt tttggttaaa
    17221 ttcagctatt ccatactcct ctatttgttg tttactagta agacctaatt ctttttctac
    17281 ttgtatttca actggtaatc catgtgtatc ccaaccagct tttcttttta cttgataacc
    17341 agacattgtt ttatatctac aaactgaatc tttaagtgtt ctagataaaa catggtgtac
    17401 tccaggattt ccattagctg ttggaggtcc ctcataaaat acgaaacttg ggtcatcttt
    17461 ccctttttct aaagtttttt caagtatatt tatatctttc caataatcaa aaacttgtgc
    17521 ttctgcttgt tttacagaac tgtctaccaa tggcttaaat ttcgccatgt aaatcaccct
    17581 ttcctataaa tattataatt ccaaaatttt ttattctttc acataaattt aaatactaaa
    17641 aaactcgccc cctttaaacc aaagggacga gttataaatc gcgttaccac cctaattcta
    17701 tatgtaaact aaatactagc tacatataac actctaatag tataacggta ctaaccggca
    17761 cagcttagta gaatttaatc gttcagcctg cagctcaaga gtgattttta cctttataaa
    17821 ttcattggtt ctcagcatac ccaattctct gtaaaattat ctaaagataa acgtctctat
    17881 caacgctttt aaaaatttat ctgtgtttat atgaaattct ataacaaata atttgaatag
    17941 tcaatatatt tttgaaaaat ataataattt ctatttttct tacattttta tcctattttt
    18001 aatttttgtt atagatttct caaacttaca caatgattct acataacaaa taaccaaatt
    18061 acaagcttat tctaaagttg tagcagcttc atcattacta taattataca ctgttgttcc
    18121 ttcaaatgca tttacacatt tttcatctac atcataaaaa atctcatcta cacttcttat
    18181 ttcatcttct aacaatgatt tgaatttatt tctaaatatc ttaaattctt tgactaaagc
    18241 atcatactct tttcttatct ctataacacg gttattagct tgttctataa tttgtctagc
    18301 ttttaaatca gcttcttcaa caattatctt agccttttta ttagccgcgc tacaagtgtc
    18361 ttctgctgca ctttgagcag ttattaaagt agcttttagt gtttcttcaa tattttcata
    18421 cttatttact tggtcttgat ataaccctaa tttttctcta agagctgtat tttccttaca
    18481 tagagactca taatcttcct tgatgatatc taaaaattca tccacctctt catctctata
    18541 tcctcttaaa ccttttttaa actctttatt ttctatctca attggagtta gcattacatt
    18601 tcctcccagc tataatttaa attagtcctt atacaattaa tcttgcttga acttttattt
    18661 ttccttttct agtaatatct cctatttgtg ttaccttagc tcttccttta cctctaatag
    18721 aaatcaaatc atcatttttt actattttag aagttgaagt tatcttttca taattgacat
    18781 ggactttttc tccatttatg tattttgcac tatcttgtct agatatattg taaataccac
    18841 ttatcacaca atctagccta tctgaagata ctgtaaatga cacttcttta tattttgaag
    18901 aactattaac aatattttct ctggaaattt cctttacaat tacattattt cttgaaactt
    18961 tttctaagtt tacaattata aaatcgcaaa tatcactact tacaactact tgacaaaagc
    19021 tatcatgtat aattatatct ccaatttttt ctctttttat acctagacct agtattgacc
    19081 ctaagtaatc tttatgagat atatttttaa atttaaaatt cccttctatt tgtaaaaatc
    19141 taagagtatc ttctatatct tcatattcca tgtaaaatgg ataaataaat acagtgcttc
    19201 tttcagcttg ttcataacct ccatccacac tgtattttat ttcatttgta gaatttaata
    19261 ttgctacagc atttttcact tcatatggat taagaaactc cgtagactta acatcatagt
    19321 tttttataca actattagcc ttgtctatca ctttaaacat tttatttttc aagtctatat
    19381 cctttatgtg atttgttagt tttaatttat ccatcctatc accttagaat ataaccaata
    19441 ctaattgtct taggaacatc aataatacta ttgcaattaa aggagaaaaa tctataggcc
    19501 catttgtata tttatacatt atggacctta ttggcccttc tattggctct gtaagatttt
    19561 ctaaaatatc aaaaatttta ctttgtcttc catttggaaa ccaagtcatc aagcttttta
    19621 taactatcat ccatgctatt atatctaaaa gataataaag tgcaattctt attgttccca
    19681 tacattaacc gcctttttac tatttatttt gccaagggaa gaatgcttta ctttctaatt
    19741 cttttttcat atttgcatct atatccacat tattaggagc tagtataaat attgatttag
    19801 aaaccttctg tatacttcca tctaatacat aaactgcccc attcataaag ttaaatatag
    19861 atttacgaac ttcagaatta gtcaatcctt ccaaattcac tataactgcc cttctttgtt
    19921 ttagatggtc tgctatagtt gcagcttcat cataaacctt aggttcaact attacaactt
    19981 tcatttgact agttgtatgt aaatttacaa ttttatttgc ttttgcagta ctaaatccac
    20041 tgttcatttc ttcttcttga actatatcgt ccataccact ttcatattca tcttcaatgt
    20101 aatcttcttc ttcatcaact atccaattct taaatttaga tattattcca tttgacatta
    20161 ttaacttcct ccttaaaatt tattcaattt gagtaattat tttttatcgt agtttctttc
    20221 tccaaagatt gatgttccaa ctctaacaat agtggcccct tcctctatag caatttcata
    20281 atcgtgactc attcccattg ataaaacatc cattcctaca ttagggatat ttagttcttt
    20341 tatttgtttt gataaatctt taagaccttt aaatacacct cttatctcat cttcatcttc
    20401 tataaaaggt gccattgtca ttagaccttt tatttttata tttttatatt tttctgacac
    20461 ttctttgaca aagtctacaa cttcttctct atcaagtcca tgcttagatt cttctttaga
    20521 tatattaact tgtactaagc aatctatttc tctgtttatt tgctctgcac gtttttgaat
    20581 ttcttcgcat aatgcaattc tatctaaaga gtgtatcata caaactttat cgattatgta
    20641 cttaacttta ttggtttgca aagttcctat caaatgccag tttaatttgt tacctataat
    20701 atcatacttt ctagctaatt cttgtggttt attttcacca acagaagtaa ttccttccct
    20761 cattgcctca ttaactaagt ccacatcaac agtctttgta actgccaaaa gggtaatctc
    20821 cttgctatct ctatctactt tttttgcagc tttatcaatt ttgcttctta tctcagacaa
    20881 attgtcttta atagaaccca ttattatcac ctactttatc cttatatttg tgtttatact
    20941 gttaggtctt aaaattattt tgtcatatag attaacactt gtaactccat ttaggtcatt
    21001 tttataataa tccacaaata cagaagattc attctcataa gttattcctt ctaatatgac
    21061 aaattttaca ctttgtgatt gttcattaat tacatataca ccacgtttat tgtcttttgt
    21121 ttttatagaa gttttaggta tttttaaaca ttccatctga ttatatatta tatcaaattc
    21181 ttcgacactt gtatcctgat ttgcaacaat ttggttactt atttttaatt ttaccattat
    21241 tttattatta ttttcatata ttttgtaaac ttttgcatct attttttgct cacgatattc
    21301 aattattaca ttttgatttt tttcaaagtt attagaatct tctttactga tgtatgtaga
    21361 tagataattg ctttggtcat tggcatcttt ttctatagct ccttttacat gaatctttgc
    21421 atcgactttt tcatttttta acaccaatgt atctacattt ttgctaatta tcattactaa
    21481 tatattaaat actaaatata taaaaatacc aagtatcact aatctggtat atttaacctt
    21541 tttcaaagac tctcccccta taaaatttct ttcattataa gtacttcttc taaaaaatgt
    21601 ttattccttt tttataacct aatattttac attctaataa ttattttttc catattaaat
    21661 ttatttttta tcaatcttcc tatacaagac tgcattattt atatataatt atattataaa
    21721 gtataagttt aatttacatt ttatacgtta agcttacttt atatgtttta tagttatttt
    21781 tatttttaga tgcaatataa aaccaattaa gatttaaaat aacttttgtt ctgttgacat
    21841 ttatttaggt aattatttat gcattaggat aacgttgtca caacaaaagt ttatgtccta
    21901 aaaaaaatac aaggaggatt ttcttatgtc agaaatttta ttaggaacag gtttactttt
    21961 attggttcta tgttgtttca caatttttag ttacaaggct ccatatggta tgaaggctat
    22021 gggagcttta gcaaacgctg catgtgctac tttcttagta gaggcattca acctttcttt
    22081 acttggtgat gttctgggta tggaattttt tagaagtgtc ggagctgcta atggtagtct
    22141 tggtggagtt gctgctgcta tacttgtgcc tttagcttta ggtgtatctc cagtttatgc
    22201 agttctaata ggattatctt gtttagattt ttctatatta tctggattcg ttgctggata
    22261 ctttgtttct ttcttaatta aatttataga gaaaaaagta ccacctggag tggatttagt
    22321 ggttgtaatt cttctatgtg caccactatc tcgtcttata gcatcaaatg tagacccatt
    22381 agttaatagt acactactac aaattggaca agttttgata gaagctacaa acattagccc
    22441 tataataatg ggaattatac taggaggtct aataacagtg gttggaacat ctccacttag
    22501 ttcaatggct cttacatcta taattggtct tactggcctt cctatggcga taggagcatt
    22561 aggtgctttt ggttcagctt ttatgaactc aacgctattt gcaaaattga aattaggttc
    22621 taaaaaagat attatatctg ttgctattga accattgact caatcagaca taatttcagc
    22681 taatccaata cctatatatt ctactaattt ctttggagga gccttttctg gtatcattgt
    22741 agccttgatg ggtcttgtaa acatgactcc aggtacagct acacctgtgg ctggttttgc
    22801 tataatgttt gcttataatc cagttcaaca agttcttata acagctggtt tatgtgcttt
    22861 attcaatgta attgcaggat ttttaggttc aaaaatattc agtaccttta aagttcttac
    22921 tgctggtgaa atacgtggta ctgatgtaga agaagaaatt gcttaaaaaa acaataagat
    22981 ttataaattt atatctcaag tagtagagtt ttatattgta ggcaatttta tcaattgcaa
    23041 acgttttatt ttttatttat gtttatgatt attatgtgtg ttgaatattt agataaattt
    23101 ttatttatta tttttgttta gttttttatt tggttgatat attaggaata agaattagta
    23161 tacttcatta ctaattaaat aacataactt tttattaaat aacataactt tttagatata
    23221 taaaaaactt tatattaatt agatattatt aaaataaaag cgatacatga ccttttaaat
    23281 gtccatgtat cgctttattt ttgccacaat cttaacaact aatttttaaa atttattatc
    23341 ttaactataa tatttaaata catatactta tttaatttaa ccatataaat atttaattaa
    23401 atattatcat atgtaatata tctaattttt aaatgaatgt ataggggctg gaatccttcc
    23461 tcctctttga gtaaatagtt cagatgaatt tgtatttata ggcattactg gtgctcgtcc
    23521 taaaagacct ccaaattcta ccatatcacc tacatcacat cctggggctg gtataattct
    23581 aactgctgta gtcttattat taatcatacc tattgctgcc tcatcagcta tcatggctcc
    23641 aagcgtacct gctgtagtat ttcctggcac agctatcatg tcaagaccta cagaacaaat
    23701 agcagtcatt gcttcaagct tatctatact taaagcgcct ttgataacag catcaatcat
    23761 acctgcatct tcagatactg gtataaaagc tccactaagt cctccaacat gtgaacatgc
    23821 cattactcca ccttttttaa cagcatcatt taaaagtgct aatgctgctg tagtcccatg
    23881 agtaccaaca acttcaagac ccatttcctc taatatgttt gctactgaat caccaatagc
    23941 aggtgtagga gctaatgata agtctattat tccaaatgga acattcaatc tactagaagc
    24001 ttcctttgcc acaagttgtc caactcttgt aattttaaat gctgtctttt taactgtttc
    24061 tgaaacaaca tcaaatggct ctccttttac tttctctaga gctctcttga caacaccagg
    24121 accacttaca ccaacgttta taattctatc agcttcacca acgccatgga aagctcctgc
    24181 cataaatgga ttatcttcta ctgcattaca aaatactact agttttgcac aaccaaaacc
    24241 ttttgcatct tttgttaatt ctgcagtttc ttttatgatt tctcccattt ctctcactgc
    24301 atccatattt ataccacatc ttgtagagcc tacatttact gaagcacata ctttattagt
    24361 acttgctaaa gcttttggaa ttgacttaat tagtatctta tcaccttttg tatatccctt
    24421 ttgaactaat gctgagaatc caccaataaa atctatacct aaatcctctg cagccttatc
    24481 caatgtctgt gcaaacttta catagtcact ttcatctgtt gcacctgcaa taatggaaat
    24541 tggagttact gatacccttt tatttacaat tgggatacca aattcacgct ctatatcctt
    24601 tccaaccttc accaaatctt tagcagagct cataatctta ttgtatattt tttctctagc
    24661 tttatctcca tcagggtcta tacaatctaa taaagaaatc cccatagtta tagttcttat
    24721 atccaactgt tcttcatcta tcatctttat tgtttcaagt atatttccta cattcactgt
    24781 tatcacctcc ccttactgtc tactacagat tatgcattga attaaatatt tcttctcgct
    24841 gaatttttac atctactgat aatttcttac ctctttcaac caagtcctca accgttttct
    24901 caaaagaatt taatgatttt tctaagtcaa ctatcataat catagtaaaa taatcctgta
    24961 atatcttttg tgatatatct actatattga tattttgctt gtataattca tcactaattc
    25021 ctgccactat acctggttta tcctttccaa ttactgttaa aattgctttc ataataatat
    25081 cctcccttat ttttttatga atcttatatt tttacaaatt gaactatgta ttaacataca
    25141 tttcatttat ttgttaataa atcacttttt atgtatatat ttaatatatt ttaataccta
    25201 tacattcatt tgtcaatttt ttttcaatat tctattattt ttatactatt tagaaaattc
    25261 acgtattata tatgttttct caacattaaa tacagttttc ataataatga aaggtattac
    25321 ttagtaatct catgagttta taaataatac ctttctaaaa attatttttt ttcttttatg
    25381 aacttaatta tactttttct agtatcagaa tttacaatta atatagaacc aatcataatt
    25441 ggtgttagta tgcaagctaa aaaaataatg tcttttttta gattatattc tttagattct
    25501 aatttataat tattatttat tattccattg taatcactta tatttgactt atttttattt
    25561 gtatcttgat ttttattaga aatactttct ctataaggaa aagaatgttc attgatgcca
    25621 aatattgatt ttaaatttaa atcataatca ccatcatttt ctataataga gcttttattg
    25681 aaaactcctt tttctttatc agaattattt tctttattac catctttagg tatattacct
    25741 tctttgggta tatcaccttg aggattttta ttttcattgc taccagtact tgattctaca
    25801 tcatcttttg gagcatttgg ttgtttttca tcagaattat cattttcatt attattattt
    25861 tgattgttat tactatcatt attatcattt ccattatttc cattttgact gttatcatcc
    25921 ttatctctat cagggtcgtc tctacctcct cctccacggt caccatcaat atcatcattt
    25981 tcctgttcat catctggcgt ctcttggttg tcgccacctc ccattataaa acctggttta
    26041 aaaactatat ttgaatatcc ttcttttaat cctcctacca ctcttattct aaagcaacgc
    26101 aacttaaaat cttcaaagaa aagtatagct tggtctctaa tatcctcctg ttcttcagat
    26161 atccaattga ttccgtcgct tgaatattca acaaaaacct tacttgcact atacggcatg
    26221 tcataaaata aagcagctac atatcctttt ttcgtatttt gaaattccaa ttctaaattg
    26281 tctattggtt ttttatccat aacatatata ttcaaaatag gaactacatc atcatttatt
    26341 ataatttttt ctttatttaa tgtttctgtt ttgaactttc ctgttatgtt aaatttttct
    26401 cctttttcta atttttcata ataatcagta aaatcccatt ctacatctat atcaagttga
    26461 ttaccactag atgtttctaa taccatatat tgtggaaatt ttatattttc tattttgtca
    26521 tctttactta cttttatttc ttcactaaat acaccaatcc ccctataaca acatttcaca
    26581 atattgtagc cagagtcttc agctatagag ggtataagtt cattataact atcaattata
    26641 taaactttct tgctttctga tataattgat tgtaccaact tattattatc tcttaataac
    26701 tcattttcat tgttgttact atatgccttt attgaagatt cttctatctc aacatcacct
    26761 ttagaataaa cacctatagc acgctctcca gtcacttcaa tatccttatt tattattcta
    26821 atatcatttt cagtataaat tcctattgca tcttttccat ttgcctttat tttttcaaca
    26881 gattcatagg atgatttaat atataagtct cctccttcct caacgtataa tgctgtcccg
    26941 tcagtagcaa ttatgttatt tataccaata cttatacttc caccattttc tacatgtatt
    27001 actccttctt ttcctccttc acctattata tttagttcat tatcatcaat aataaatctc
    27061 ccatgatttt ttatcaatat tttatatttg ttagtatcta ttgtaaaatt gctgtcataa
    27121 ggaatataaa atctaaactc ttcgtctatt accatatcgc aagaaagagt ataaactatt
    27181 ttttctttat tatttttatt ttcttgaacc cacctttcaa aatcttcaag acaattttcc
    27241 tcttgtccaa aaactttata tggaaaactt ataaaacata aaactactat acttataaaa
    27301 ataaatatct catatttttt cattttacac tcctagaaat tttttagctt taaacaatct
    27361 tgtcgaaaca tatacttcac ttactataat ttttccataa ttatcaatta ttgtcaattt
    27421 atataagtac ttttattaat tgctataaat aaaaagctac ttactaaagt aaacagacgt
    27481 ttaactttaa taagtagcta tatttttata acaaaatagt tataatatta gaacttcctt
    27541 catttacaat tttttgtaaa gtcttttgca tcttgactct tatttcttct ggcatagtat
    27601 ataatttact ttgtaattgt tcttttacta agtcatgtaa tgatttgcca aacatatttg
    27661 attcccataa gtctgctggt tgctcttcaa atacttccat aagatatttt atcatctctt
    27721 caccttgatt ttgatttcca actattggag aaacctctgt cgatatatct gcttttataa
    27781 tatgaagtga tggtgcattg gcttttaact tgataccata ttgttttcct tgtttcatta
    27841 tttctggctc ttccagacta agttcttcta aagaaggagc tactactcca tatcctttta
    27901 tcttggcatc tattaaagca ctttctattt tatcatactc atttttaact ttagatagtc
    27961 tagttatcag actaagaagt tgataatctc cttcaatttt aaatccactt ttttcttcaa
    28021 ggacattata gaataaatct tgctttgtct gcaaatcaat atttataaca ccttctccta
    28081 actctacatt atcaacacct gtatcttcca aaaactctaa ttcagaaaat ccttgcataa
    28141 taccttctat atctcttatt ttacctatat ctataatact ttgttttaat gttgttatta
    28201 tgctactttt tatccaatga tttctttcaa gaccttcaac ccattttggt aggttgattc
    28261 ttatttctgt aagtggaaaa tcatataata cagcttccat aacctcttct atatcttctt
    28321 cttccatttc aaccacattc attggaagaa ctggaacttc atacttttct tccaattcac
    28381 ttctaagcat gctcgtttcc tcactttttg gacttaacgt atttaaaacc actgcaaatg
    28441 gttttttaag gtttttcaat tcctgtataa ctctctcttc tggctctaca tagctctttc
    28501 tgtcaattcc agtaactgaa ccatctgtca agacaactat ccctattgtg gaatggtctt
    28561 ttataacctt tttagttcct atttctgctg ccttttcaaa tgtcatagct tcttgtgacc
    28621 aaggagtaga tactaatctt tgttttccac cttcctcatg ccctaaagct ccttcaacta
    28681 tgtatccaac acaatctacc attcttactt ttaaagatac tgtgtctttt atttttattt
    28741 ctactccatc tgctggtaca aattttggtt ctactgtcat tattgtttta cctgaaccac
    28801 tttgaggtat ctcatccctt gttctatcct ttttaaattc attgtctata ttaggtataa
    28861 ccaacttttc cataaatttt cttataaaag ttgattttcc tgttcttaca ggtccaacta
    28921 ctccaatata tatatccccc tgagtccttt tggatatatc ttcgtatatg ttattattca
    28981 tattattcct cctatacatc taatcttatt aaattatatt tggatttcga ggttaatatt
    29041 cttaaaatgg aaaaataaag accagcaata ttaatttcgt ttacagatag aaattctttc
    29101 attttctgct ctatagtttt cataccaaac ctgtctacta tgtattacta tatctcctct
    29161 ttgaagtatt ctagtattgg agtctaaatg aagttgtgct gttctatcaa tccctgaaca
    29221 aatacagtta aaaaatttta tatacatata aggatacttt taagaaacat attttagtaa
    29281 agcattgtct cctacatctt ttacatatct catttcaaat attttacttc caacatcttt
    29341 gataacaaat gatttatcag tcatatactc tgaaaaactt gcagatacta tatgtttttc
    29401 tattccaaca gttgttccct taggatttat ataacaaaac aatattatga tatgtttcca
    29461 gaagatttag gtgttcatga tagtgacata tctttaatga ttacaggaga aagtataaag
    29521 gaaagaaata agatactatt aaacaatctt gtagatactg gatatatacc agctaaagat
    29581 ttagacataa ttaatgatat aattatttct ttttatcaaa atctattatt cttaaaaaag
    29641 aacacaggaa aaaattctga tgatgatgaa ttaactatga aaacgatttc ttctattgaa
    29701 tacataataa aacatgctaa ataaaattaa aatatggctg tctcaaaata gagataagcc
    29761 ttttttattg ttgaaataat aaaaatacat ttaatttcat acaaaaagag tgtctcataa
    29821 actaaaaagt tcattttgag acacccctaa aacaaattta ttatttatta tacaatagtt
    29881 tatatatcat cacctaaaac tacttcttcc atttcatgct ttttacttct catcattagt
    29941 tctattccaa cttctttagg atttgaacct ttctttatta cagaatatat agcattagtt
    30001 ataggcatat ctatatctaa tttttcagcg acatcatgtg ctacttcagt agcagttata
    30061 ccttctacaa ccatctttac ttcttttaag gtatcttcta aactcatacc tttacctatg
    30121 agtataccag ctcttctatt tctactatgc atacttgtgc aagtaactat taaatctcca
    30181 atacctgaaa gacctgcaaa ggtagacata ttagctccca tagcaattcc aagtctgctc
    30241 atttcactaa tacctcttgt cataagagct gcttttgcat tatcaccata tcctaatcca
    30301 tcacatatcc cagctccaaa tgctataata ttttttaatg ctcctccaag ttctactcca
    30361 actatgtctg gattcgtata aactctaagt ttagggctca taaataagtc ttgtatcatc
    30421 tgtgctattt ttaaatcttt agaagcaact actacggtag taggaatatc ccttgctact
    30481 tcttcagcat gagacggccc agatagtatt acatatggat tttgtggtaa ttcttcttca
    30541 cagacttgag ataacctaag ccaagtccct ttttcaagac ctttggctac attaacaata
    30601 acttgtcctt cttttataaa tggctttatt ttttggcaag tacttcttac agcctgtgat
    30661 ggaactgcta aaattattac cttacaatct tttatagttt tttctatatc agtacttata
    30721 gttatattat ttggaaataa tactcctggt aaatagtctg tattttcttt agttctgttt
    30781 atttttttag cttgttcctc ttttcgagtc cacatgctca catcattacc tttttttgca
    30841 agccctaaag ctaatgcact tccccagctt ccagtaccta atacacatac tttctccatg
    30901 tttaacacca cctgagtata atatatttac tattctttct tttgaccaat ttttctctct
    30961 gtcccattta ataatcgctt tatatttgct ctgtgattat atattactga tgcagttaag
    31021 aacaaagcta ctattaaacc agctttattt tttaccataa tcataaatat tggtgagcat
    31081 cctatcccta caacagaacc taatgaaaca tactttgtta taactaccac caatataaat
    31141 actgctagac acattagtgt tattactgga tttacagcta gcattgcccc cagcgaagtt
    31201 gcaacacctt tacctcctct aaatcctaaa actgctggcc aattatgacc tgccacaaca
    31261 catataactg ccagatatcc agctaaaaga gtatctattc caaccaatct tgctgcaaac
    31321 tctgatatta aaacagccat cacaccttta agaacatcac ctaaaaatgt cattgctcct
    31381 gctctttttc caagtgtcct aagtacattt gttgaacctg cgttaccaga accttgagtc
    31441 cttatatcaa ccccagcaat tcgctttgca actatgtatg aggtagatat atttcctaaa
    31501 agatatgcaa ctacagcaat aattatataa ctaaatatct ccactgaatt tccccccttt
    31561 agttatattt tagatattta ttttttattt ttttgtctat actcaaactt tatggaagtt
    31621 ccttcaaatc caaaattttc tcttatctta ttctcaaggt atctttgata tgagaagtga
    31681 gttaattcct tatcatttat aaacaatgta attttaggag gtctaatgtc agtttgagtt
    31741 ccatagtaaa tttttaatct tctacctttg tcagatggtg gttgatttaa cattacagct
    31801 tctccaatta cttcattcaa tgctgaagtt gatattctct tagaatgttc atttgacaca
    31861 tattcaactg tatctagtat cttgttcatt ctttgattag tctttgcaga aacaaataca
    31921 attggagcat acatcataaa tggaaatttt tcttttatat cttttgtgta attgctcata
    31981 gtcttattat ctttttctat taaatcccat ttattgatta caaatatgca tccttttcct
    32041 tcatcatgtg ctatacctgc aacctttgta tcttgttctg ttacaccttc taaggcatct
    32101 attactatca atactacatc tgctctatct acagcactca tagctcttat tacactgtat
    32161 ttttctattg tctcatatat tttacttttt cttctaagac ctgctgtatc tattagaaga
    32221 aatttctgtc catttttttc aaaataagta tcaattgcgt ctctagtagt tcctgcaatt
    32281 ggacttacaa ttactctttc ttctccaagt atcttattaa gtatagaact ttttcctgca
    32341 tttggtttac ctgttatagc tactcttatt atatcttctt catactctgt atctaatcct
    32401 gctggaaaat tttcaactat ctcatctaat aaatctccaa atcccatact gttggctcct
    32461 gaaactgcaa aaggcgttcc aaaccccaac tcataaaaat cgtatatatt atcaaattga
    32521 ctttgactat caatcttatt aactactaag attactggtt tttttgtctt tctaagcaat
    32581 tgtgcaattt ctttatcagc agctgttatt ccagccttac catcaactat aaaaagtatt
    32641 acatgtgaca tgtccattgc aagcatggct tgatttctca tttgagataa tattatatct
    32701 tcgctatcag gttcaattcc tcctgtatcc actaatgtaa aatatttatc taaccattcc
    32761 acttcagcaa aaattctatc tcttgtaact ccaggtgtat tttcaactat cgatatcctt
    32821 tttcctgcaa atttattaaa tattgtagac ttaccaacgt ttggtctccc aactacagct
    32881 acaactggcc tacttatact cattttgttt ctccttccat cttttgtttt ctattttaaa
    32941 attttatcca caaagtcttt accttcattc aagcaaggga taatttttat tttcataagt
    33001 tcttctaatt gatttaattc aatattatct aagaaaattt cttcatctgc ttttagcata
    33061 cttcttgtta tataaagagc ttctcctaat tctttatttt caagttgttc ttttaaatct
    33121 ttagctgtta aaagaccaga tacagttatt gtctctccaa aaaatttatt tttaatttca
    33181 tagacattta tttgaagatt tttaaacttg tccatcatag catttgccat actctgtata
    33241 aattcatatg cagaatgacc agtagctatt gatactttct tatctctttt taaaatatcc
    33301 tcaggcaata tatttagata ctcttcaatc tctgttttta acttacgtat catacctaca
    33361 ccatcttcaa actgtaaaaa accttcatat tcttcatatc caggcaattc actattagat
    33421 agtatataaa attcatctga taaaaatgca aatcgagtac ctaattgttt aagatatttc
    33481 tgttgcattt gatgtatttg ctctatagtt ttacttgcgc tcttaccatt aaatatattt
    33541 aattctacta gattttctct atgctttgta atcccaactg gaactatagc aacactattt
    33601 acatacggat aaagttgagc tagttctttt attgttctat ccaattcctt tccatcattt
    33661 atgcctggac ataaaacaat ttgacagttc atttctatat gagcatctgc caatctcttc
    33721 attataccat ataattttcc tgcaaattta ttacttatca ttttttgtct taactctgga
    33781 ttagttgtat gcacagatat atttatagga cttattctat attttataat attatttata
    33841 tcttcttcac tcatatttgt aagtgtgaca aaatttcctt gtaaaaaaga caatcttgaa
    33901 tcatcatctt taaaataaag agtttctctc ataccttctg gcaattggtc tataaaacaa
    33961 aacatacact tatttctaca gcttttagct tggtcaatta ttggatttgt aaattcaaca
    34021 cccaaatctt catcatagtc tttttctatc tcgtatatgt agacttcacc atcttttttt
    34081 tgtatttcta cctctaaata ttcatcactt agtaagaatc tatactctat tatatcatgt
    34141 attggttgtt cattcacaga tataagtaaa tctcctacct ctatacctat ttcttctgca
    34201 atactatctt tgtaaacctt acttataata ttatttactt tttttacatt tacttccaat
    34261 attttcacca ctcttttgta ttcatcaatg cttattataa tatattttta tatatagttt
    34321 acttatttat tatattttat ggtagcattt ttaagcattt catgtcataa taacacattt
    34381 taattctaat agtcaatata agtagatagc tataaactag attaaaacaa ataatattca
    34441 aatttaagtt ttttaaaaat ttgaatatta tttgttctta aaaaatttat aaatttaatg
    34501 ttttactatg attagcgtcc cattcgtcat atcatgaacc attccaccta cacactttga
    34561 catcaacaat gccttatttt gtaagtcttt ctcatcgttt gcataaaata ttggacaacc
    34621 tccaccattt ttcatattct tatcaagtgt aactatagct agggtatatt catttaaacc
    34681 tatatccatc cccatcttat gcacttcctt tctttcctat tttataattt tttagtgata
    34741 agttttttcc tttagagctt gaaagtattg ggcatgactt tacagcttcc attacttttt
    34801 ctacattctt atctactggt aaataagcaa tcattatact ttcatcctct ttatttcttc
    34861 taggtaatgg tacaaatgaa ggttctccat aatctccata taaacctaac ctcgaatata
    34921 tattgtatac tattgcttgt ctttgaccag aatcaaataa tattcctgca ttagcataat
    34981 ctttattctt aggaattatt tgtattccta cacctctatt aatatatact tctctatcac
    35041 tttttagacc tatatttgtt atacctttta aatctccaac ctttagtata gactcgtcca
    35101 caaaactaat ctcagcaggc attacatcag ctatgtctcc aatacttttt ctagtaagga
    35161 gtttttttaa tataaaagct agcaataatc cacaaattga acttattacc aaactcatcc
    35221 cttcacttat tttcgtttct gcaagtatta catagtacaa ccctattgtt aaaaaagagg
    35281 taactatgca catataattt ctcacttcat aggttctagc tatctcttct atgaatgcag
    35341 cacctctctt tacaagctga acttcttcta aattttgcaa cgtatttctc ctatttgctc
    35401 tcacttgtct aaattgttct gctgctagag ataaaaatgt tatagatgta taagaacgat
    35461 ttataagagc tggaaccaat aatgctccta atgaagaagc gacgaatgct aatataagtt
    35521 gagatattaa aacatttggt tgcgttggat actgtttttg gtctaaattc aacattataa
    35581 ttctagatgt tataccaata ataacagcaa caaaaaatac tctatccatt aaatcactcc
    35641 taaaatattt tagtttaaaa ttttacatgt aaatctacaa agtctttcta gaaaaatcac
    35701 tctgctttcc ttttgatgtc tctatgatag gtgtactttt cactacatct atcatgacgt
    35761 ctatatcttt gagtattggc atatacggta taaccacagt acgtttttcc aaattggtct
    35821 tagatatagc aacaatatca acctcatcta catctctatc tatccccata tgaataaata
    35881 gattatgtat tatagcttgt ctttgcccta tatcgtttac tattccaaat gcacctaaat
    35941 ctcttggtat aacttctatc gccagacatt catttctata cttttctctc gtactttcta
    36001 gacctatatt ggttattatt acatcattta ccattaaaat aggaccttca aagcttattt
    36061 ttgcaggaac tatatctgct atatctgcaa tactgtttct tcttaaaaat cttctaaaaa
    36121 tcaaaccaac aatagctcct gacacaatag ctaagattgt acaataaaaa aagctaaggt
    36181 cgtactttct tgcaaaaacg atataaacta tcgaagatac tagtgcagaa aaaagactta
    36241 tataacttct agattcatac gtagatgcta tttcttcaac gtaagcatct ccttttggta
    36301 ctaattcttc attatcgata ttctttagtg ttattctttc ttgttccgca agaccttgaa
    36361 actgctgtat tgctactgca aaaaatgtca aggctgcaaa ctccttatct ataagtgcag
    36421 gcaatgctat agcacctaat gaagctgaaa gcccagatat aattatctgt tctaaataat
    36481 cttgtggtct tgatgggtat tgtttgtctg taactcttaa aactagtcct ctacataata
    36541 ttcctacgac taatgcaact ataaaagagt gtctaaataa atttgcattt aataaacttt
    36601 cttccatttt ctcagctcct tctcttatat agtttgtgca aaaaacaaaa aaaatttcct
    36661 tctatttaag gaaatttttt tgtaatattg taactataaa ttcgctacca atgccaagtt
    36721 cactttttac ttttatacat ccatttagtg atttaactat atgctttgtt atagccaatc
    36781 ctaaacccgt tcctcctaca tccctacttc ttgctttatc taccctataa aatcgttcaa
    36841 atatgcgttc tacatcttct tttggtatac ctacaccatt gtctataact ttaattacta
    36901 ttttttcttc atcttttaac actacaactt gtacaatccc attatcttgg gtatacttta
    36961 tagcattatc aactagattt aagaacactt gctttatata gtctttatta gatagtatac
    37021 ttattgattt atcatcacat ttatataaaa cttctatatt tttttcacta gctgaatgtt
    37081 gagttatttc atatacttct ttaaatacat catacactac aacattttcc ataagaagag
    37141 tatctttatt ttctacaaac gataacagca atatatcatc aatcaatctt tttaatctat
    37201 ctgattcgct ttctattatt tctaagaatc tatttctagt attcacatct atattttcat
    37261 ttgactttag tgtttcgaca aatccactta tagatgtaag tggtgtttta agttcatgac
    37321 ttacatttgc aacaaaatca cttctcatat tttcaagttt aactttttta gtaatatctt
    37381 ctatatttac tatcgaacct attattacgt tgttagtatt ttgaagataa actgggtcta
    37441 cttttatttt atatactata tcatctttag tagtaatatt ggcagtttca ttatctttag
    37501 agccaataaa tcgaagtatt tgttttaata tttcttcttc ttttattaca acattaatat
    37561 tatgaccttc aactaattga tttggttcac tctttatcat ttcttttgct tcatcattta
    37621 tcagaagtat attgccattt acatctatag ccaaaattcc atgagatata ctctttaata
    37681 tagactttaa ctgtaaatgc ttatactgca cttcttctaa tgtcttatcc atattcttta
    37741 tcatatgatt aaaatttcta gctaattcac cgagttctcc tttagctgat atattaagcc
    37801 tagcatgata ttcattatta cttacttttt ttgagacgta tataaattct tttaaatatt
    37861 tccttaatgt tattgtgtat cttacagcta atatcacaat agctatggac aacataacaa
    37921 taaaaaaata tacactattt aaatcttcca caagataaca ctcctaaaat ataacctttt
    37981 taatctattt tgtatcctac acctcttata gtctctatat atttttctga tttatcttca
    38041 tcttctattt tttttcttaa atatcttata tgaacatcta ctgttctagt ttctccatag
    38101 tattcatatc cccatatttt atccaaaaga taatttcttg aaagtacttt tcctttattt
    38161 tgaatcaata gttttaataa ttcaaattcc ttaagagtta actctatctt ttcagaacct
    38221 ttggtaactt catgttttga taaatctagt tttaaattac ctgtagtaag tatattgttt
    38281 tcttcaccta agctagtcaa attatatctc cttaaaacag aactaatcct agctaacaac
    38341 tcttttatac taaatggctt agttatatag tcgtcagcac ctatttcaag cccttcaacc
    38401 ttgtcatttt ccatattttt agcagtaagc attataacag gaatattttt taagtcctta
    38461 tcacttctta tttttctcaa aacttctatt ccacttatat ttggtaacat ccaatctaaa
    38521 agtattaaat ctggtttaat ttccttggcc tttataaatc catcaaatcc atcatatgaa
    38581 taactaactt cgtaatttga cacctccaaa ttgaatttta atagctcaac tatatgcatt
    38641 tcatcatcta taacaagcac tttagtattc attaaaaagc tcctctctat tttatctgta
    38701 gtaccgttcc tattcgttct gatgccttat tatgttttct ataagagtgg aatttatctg
    38761 ctctacaact agtgcataaa tttaaattta ttatattttc ttttttaact ccactacata
    38821 taagcatata ctcattaatt ttccataaat ctaaatagta actcccctct tttattatat
    38881 agaacttttc atcattattt gtaagaattg tgttaaattt ttctactaaa tcttcagaca
    38941 cttcataaca acaaggtcca attgatggcc caattataca tactaaatct tcgggaactg
    39001 ttttatagca ttcagacatt aattttattg ttttatgacc tatattacta aaagtacctc
    39061 tccaacctgc atgagccagt cctatggctt tatttttagc atctataatt gatataggta
    39121 cacagtctgc tgtaaacagt aaaagtggta ctttttccaa gtttgttata agtgcatccc
    39181 catctcttct tttacctatg gtgtctttat taactatgtt aactatatct gaatgtattt
    39241 gagaattact agttaaattt tcaaatgtca agtcacattc tttacatact tttaacatat
    39301 cttctctatt ttttgcatct atattcttac atgttataac tagatttaca gattttaact
    39361 tttcatcaat ttctttacaa ttaccactta aattaacata ctctttaata tcttgtacat
    39421 tttttatatt tatataatct ttcatcattt gtctcctttt tctatcaata tacttttaag
    39481 ttcatttaca aaagtattta tatctttaaa ttgtctatac acagaagcaa atcttacata
    39541 ggcaacttca tctaaatctt tcaatttatc cattaccatc tcaccgattt ttttggtttc
    39601 aatttcttct ataaaacatt tatttatttc attttcaata tgtacaacaa tgctttcaat
    39661 ctcttcaata gaaacaggtc ttttttcaca tgcctttaac aatccatatt ttatcttttc
    39721 tctatcaaaa tattctctac tattatcctt tttgattacc attaaaggag ttgtttctat
    39781 tttctcatac gtagtaaacc tctttttaca tgattcacac tcacgtcttc ttctgataga
    39841 ttttaaatct gtatgtctag aatctattac ctttgattct ttataattac aataaggaca
    39901 ttgcatctat attcctcctt tgtttaacta tatctcaaac tcatctaagc ttaattctga
    39961 acctatattt actattattg tatcacaacc tattttaagt atatcattcc aaaatataac
    40021 ttcttcatcc cctcctcttg aaaaaaaact tctacttcca tctccaaaaa tggtaaatga
    40081 gactacttta ccttcgtgaa tatccatgtc tatgtctatt ataaacccca tcctttttcc
    40141 attttttaca tttataattt ctttttccat tatatcagaa actctaatca tattgtactc
    40201 accctttctt taaaaataaa tatgtatcga agtaaaaaaa aatgacctat ataggtcatt
    40261 taaattaaaa taatgtttac agtccatgga ttacttatac atattttctc atatttttta
    40321 aagcattctt ttcaattctt gatacttgtg cttgagatat accgatttca tcagcaactt
    40381 ctatctgagt tcttcctttg taaaacctta aatctaatac caacttttct ctactattta
    40441 atttcttaat agcttcttta agtgatattt cttgcaacca attttcatca gtatcttttt
    40501 tatcttgaac ctgatccata acgaatattg catctccatt gtcttgatac actgggtcaa
    40561 acagagatat cgggtcttgt atggcatcaa gtgccattac aaccgactct acttctaact
    40621 ctaattcctt tgctatttct gatactgtag gttctttaga atttgttcta attaatcttt
    40681 ctctaacttg tagtgcctta tatgctatat cttttaatga cctacttact ctaattgggt
    40741 tattgtctct tagatatctt ctaatttctc ctataatcat aggaacagca taagttgaaa
    40801 atcttacgtt ttgacttaaa tcaaagttat ctatagcttt tataagacca atacaaccta
    40861 tttgaaataa atcgtctata ttttctcctc tgttgttaaa cttttttatt acactcaaga
    40921 ctaatcttaa attccctctt acaaactgtt gtctggcttc ttcatcacca ttttttattt
    40981 gtaataaaag ctccttcatt tgcttatttt taagaactgg aagttctgat gtgttaacgc
    41041 cacatatttc aaccttatta acttgcatat attttcagtc ctctctcaaa agtattcatc
    41101 tattgaaatt atttacattt ccaatttttt tatacttttt aagaagaatt aatttaacat
    41161 tatacaaatt ttttcatttc tttttgcaac cttgaaatta ttttcttttc aagtctagat
    41221 atgtaggact gtgatattcc aagcattcct gcaacttctt tttgtgtttt ttcgatacct
    41281 ttatcaataa gaccaaatct taattccata atttgctttt ctctgtcact taatctgtca
    41341 agtgccataa ccaacaaatc tctatctatt tcttcttcaa ttattttgta tatttcatca
    41401 ttttctgtac ccaatacatc agataataaa agttcatttc cgtctaaatc tatatttaaa
    41461 ggttcatcaa atgatacttc tgttttcttt ttattatttt ttcttaagta cattaatatt
    41521 tcattttcta tacatctcga agcataagtt gccaatttta tatttttatt cagtttaaaa
    41581 gtattaactg cttttatcaa acctatagtt cctattgaaa tcaaatcttc tacatctatt
    41641 cctgtatttt caaattttct cgatatgtag actactaatc taagatttct ttctattaaa
    41701 attgacttta cactttcatc tgtttctagc ttttgtaaaa gttccatttc ttcttctggt
    41761 ttcaatggag gaggaagtat atttgcccct cccatatagt atattccctt tggctttatt
    41821 atttttaatt taatacctaa catagtaata aagcttataa ttctttcttt caatcgtaac
    41881 attccttgtc ccccttaaat tttcacctaa aatccaggta atatatttgg attcattatt
    41941 gctccatatt ctctatcatt aaaatttgaa ataccaagta ttatatttcc tatcttttgt
    42001 tcatctactt ctatataatc agcttttaaa cctattatta tgcttgtctt attgcttcca
    42061 gcatgtttat aaggtattat tctaactcta cctgaagttt tatcatctaa acttcctata
    42121 atttcttgtg cttttttcat atctatatct tcataattaa tatttaatag tttttctgga
    42181 ataaatcctt ctagcacact tgacttaact attattacat cactttgact tattgggtct
    42241 tttaacaaat taccactatc tactaaagcc ttacagcaaa aacttttttc tagtaatttt
    42301 atatttatag tctttgtaag ctccttaatg tacttaagca ttttcaaatc tttataaatg
    42361 tattttaata attcacaact cacataagta catgcaatta aaaaagatat ttttaagtga
    42421 cttattcctg taaaataaat tataaaataa gtgcttccag aaataaaaat gtttactaga
    42481 taaaaaacta aagctacatg aacataatct tttttgctct tgcttctaaa tgaaattaaa
    42541 gttattatac tcatgattat tattttaaat ggtatagtaa atagtatatt cattgatgga
    42601 tacaaataag caacagaata ggcacctcct aaactagccc ccaacaactt atttttttta
    42661 ggattatatc ttttagtaag aatagaagta caacttataa taatataatt tattactagg
    42721 ttttctataa catagtactc aatatacacc atgtatcccc ccttaaaacc tttaaacata
    42781 ttataagata gtatgtacaa aattttatgt cacttttgat ggtcgaatcc aaaacaaatt
    42841 ctatttaaaa agaacaatga tatatgtctt atactttatg tcgccaaaag atattttttt
    42901 aatgccaaac aaataggctt ttttgtagaa tccaatatat ctaggtagaa gttattcgtt
    42961 ctacttttgg tatatttcca taaaaaaaag actacataat ttaataatat atcaagtaaa
    43021 tcttttactt atctaaaatt aaattatgta gtctgtaaat tcaaatataa atttaaatta
    43081 ttgtgctaat aatccatttg catattttgc agattcattt agtgcttgtt ctggagttat
    43141 gtctccagct atcatcattt gaagttgttt ccataagtat tcatatatct ctactccatg
    43201 aggtccaact gttaatggtc tatacatatg tttatctctt gtaaccattt cttcaaacct
    43261 tgggtctcct tggtattttt cacctttagc aactggagct ctaggtactt ctttgtggaa
    43321 agcttccatt gattctttgc tcaacatgta ttcaagaagt ttaaatccaa gttctttatt
    43381 tttacatgct gacattaatg ttaaatcatc tactgaagca aaacttccaa ctgtcttatc
    43441 ttctaatgat gttacatatc cccagtttaa atctgggaat gatttatcaa atgtacttgt
    43501 agcagcagaa gacaacatta tagtaaatgc agcttttcct ggtccaaata cactttcaat
    43561 catttcatta ctatcttttg acaaagcatc ttctggaata tactttttca tatcatttat
    43621 aaagtttgca gctttcaaac cttctgcatt attaaattta actgatttta aatcatcatt
    43681 atatatacct ccaccagctt gccataaata cggataccag ttccagttta aactcccaaa
    43741 tactttagaa ccccaacctt gtgcaagacc ccactggtct atttttccat ctccatcagt
    43801 atcttttgtt gctttttcac atattctttt aaaatcatcc catgtttttg gaggtttctc
    43861 tcctaatttt tctagtatat ctttattgta atacaataca cctggattag cagcttctat
    43921 aggtaaacca taaataccac ccatcatttt tgcatcatct aagtatagat aattatctga
    43981 agttcctgat ttttctagat aaggtgtcaa atcttctacc gcacccattt ctataaattg
    44041 agggaacatc tctgcataca tgtatcctat gtctggacct tcacctgcac ttattgctgt
    44101 tgcatatttt tctgcgtagt tatcccatgg tactatctga aattcaattt cacagttatt
    44161 ttctttttca aatttttcaa atatcggctt ccatgcatct gcatcatggt ctgttaatgg
    44221 tgcagaccac acaactaatt tttccttacc ctctttgcct ttagaatctt ctttttttga
    44281 acaccctgca agaattgata ctgacagaat ccctaccata actaaagaaa gaaccttttt
    44341 tagtttaatc atgcttaatc ccctttcaga ctttaatttg tctttttcct caaatgttta
    44401 catttaattc agatttaata ttaacaaata agactactct tgtctaatca caaaaaacta
    44461 tactaactac cataactata ttttttttct atacatatta gatttaattt acactaaaaa
    44521 acttactttt taaattttgt caatatttaa aagtgttttt aatcctagcc acaaactaac
    44581 tatttaaatt gagcaaaata aaaagaagtc tattgacttc tttataagct tacatattat
    44641 cttcttcttc ttaagaatgt aggtatctcc atactctcat catcatcttc ttcaattata
    44701 cttgcctttt taggaggctc tattttttcc tcagcaatta cttcttcttc aatttctttt
    44761 acagcttgtt ttactgttgt atttaatgag gaacgtatgc ttgatttagg cttagtttct
    44821 aaatccaagg caccattttg taatccttca aatcctgttg cgattactgt aatcattatt
    44881 tcatcaccca aatcttcttt tatagaagct ccaaatataa catttgcttc tgggtcacag
    44941 gattccataa ctaaagttga tgcctcatta acttcaaata atcctaggtt aggaccaccc
    45001 gtaacattaa gaagaacacc tttagctcct tgtattgatg tttctagaag tggagattga
    45061 atagcttgtc tagcagcatc aattgctcta gtttcaccac tagcactacc tatacccata
    45121 tgagcaagtc ccttgtcttt cattatagta gtaacgtctg cgaagtccaa gtttattaac
    45181 ccttcaactg ctataaggtc tgaaattgat tgtatacctt gttttaatac atcatctgca
    45241 actgcaaaag catctaacat tgatgtattt ttttgtacta tctgtaaaag cctatcattt
    45301 ggtattgtta taagagtatc tacttttgat ttaagctctg ctattccacc ttcagcattc
    45361 ttcatcctta tcttaccttc aaatgcaaaa ggtttagtaa ctacacctac tgtaagtatc
    45421 cccatttctt ttgccaagcc tgcaactact ggagcagctc ctgtaccagt accaccgccc
    45481 attccagctg ttacaaaaac catatcagct ccttgaagca actttactat ttcatcttta
    45541 ctctcctcag cagctctttt tcctacttca ggatttgctc ctgctccaag tcctctagtt
    45601 aatttttctc ctatttgaac tttatattca gcttttgatg tatataaagc ttgtttatct
    45661 gtatttactg atataaattc aacgcctttt agttgagctt ctaccattct attgacagca
    45721 ttgtttccac cgccacctac acctattact ttaatttgtg cacattcttc taattctacg
    45781 tcaaagttta gcatcataaa cccccttctc tcatgattca aagttatcgt atgtattaat
    45841 tatatcattt tcttctttta ttttgttaac ctttaagtaa catattccac aaaaacgtaa
    45901 attttccttt ttaaatttct tacttatatt gtcaaatatt actctttaag tataaaataa
    45961 tttacgtata tattaaatgc tctttaattt ttacgttttt tattcataat attactaata
    46021 atatatcgtc taattataga taagttatta aacaatctca taccaaaaac taatacagca
    46081 acataataaa gagaaattcc taacttttct cctatataag tcaataatat agccaatata
    46141 gcattaccta tgaaacctgt aataaaaatt acattatcat agttatcttc aaaattggat
    46201 tttatcgctc caaaaataga atccattatt gcaagaatag ctactgacat atatatggaa
    46261 taatccatag aatatgtaaa tggaatatag taacctatta ctacgccaaa tgctaatcct
    46321 cctaaaaccc ataacataaa tcttcacctc tttattttac tttgaaacac aactacatta
    46381 caatcctttt tgttaatttt ttttactttt tctttatttt tttgtatttt tcgttttatt
    46441 ttgtaaataa attcacttta tttccattat tttcctgcac ttttatatta attccatata
    46501 tatccttaag agatttagcg tatgattctg gagagtttat agcagcactc aataaatcta
    46561 tatctcctat agcttttatt atgaatggtt gtccatatgt agtatcattt actgtaatag
    46621 tagctcctga acattttatc ttactcgttg ctagtactct ttccccattt atagaaattg
    46681 ctcttgctcc agcctttttt aaatcattta aaactctcaa aatatctata tcatgtataa
    46741 tcaaatcatt cggattctgt ccgtctttta actctctctc actatccttc atagtaatag
    46801 ttatgcctgg tcctgtaaca cttgaataac cacttaattc tttaacttct tcaagttctt
    46861 tttgcataag tgtttggata gattcattac cattcttttt tgcttcttta tattcattca
    46921 aagttttttt gttgttttta agcgtttctt ttaaattttt tatttctttt tttgtatttt
    46981 ctacctcact ttcaatattt tcagtttgac ctaatgttat gtatactcta tttgggtcta
    47041 gtgattttat ataagttgat atgaaaatgc ctaatatgaa tgcacctaat ataactattt
    47101 tctttttcat actgttattt cccctctgct ttgtttatat cactatgacc atttatttct
    47161 atattgtctt ccttggtcac ttttactttg gcattataat atgtttctat ttcccagaca
    47221 ataccatact ttatattaag tgcagaagcc aatgtatcag aatcaccaat tgcttttatt
    47281 ataattggtt cttttataac agtgtcattc atataaagct tgtcttcttt taaatacata
    47341 tatgtattag aaactattct ctggtcgttt atagatatgg cacttgcttg tgctgaattt
    47401 aatttattta tcattgacaa taataaatca taattatata gtatactatc atttttatca
    47461 gagtttccta agtcttttgt agaacttatc tcaattttta tacctgttcc ttctacatct
    47521 gtatatccag ctaatgtttc atatttttct atttctgact taagtatgtc ttgttcacct
    47581 tcattatttt tgcctctata agtctctata tctttcttca cactattaac ttctgattgt
    47641 agattctctt tttctttttt taaagattta agttcttctg tgagttgctc tcctctttta
    47701 aaagttgtca tccctctatt ttctatatta ataattttaa gttgtaaact aacaagaaca
    47761 cctaatacga tacttcctat gattatactt ttatttataa atcttttttt caatatatca
    47821 cttccttaca attgtctatc cttctggact atacactgcc aacttcccat aattaagatt
    47881 tatagtacct ccattagtat ttttattttg caggtcaatc aaaattttac ttaccctaga
    47941 tatattataa tctaagttat catcattaga aagtaagatt tttatattac ttcttgtaag
    48001 catttctata ttgctttctt tttttaagtt tacataattt atttttctat aaatcccttc
    48061 ttcttttaaa taatttaaag ttttaaatac attctcctta gttttataat ttttaaattt
    48121 tatagattta ttatcatcaa cactataatc tacatctact atcaagtctt ttttactttc
    48181 attagaacct cttagttctt ctaacaaatt gcctttttta tctatataac aataattatc
    48241 ttcatctttt aatactgcaa atatttcttt ttcttttaaa cttataatta tcttattggg
    48301 aagttttctt tttatttcca cattttctat atatggattt tttataagtt tatttttcat
    48361 atctttaaaa ttgtatgcaa aaatattttc atttagattt atatttagtt ctttcattat
    48421 atttgattta gttactctct tatttccaat tacatctatt ttctttacat caaataaatc
    48481 actttttaca attatacata tacaaaaaga taacataagt ataaaaacta agactatcat
    48541 gacattattc gtatttaatt ttcttctttt tttcaaatat aatcaacccc tttggttaat
    48601 aaatacacct ttagagctta tttttcctac aaaaaaatta taatatttaa agtcaaattt
    48661 ttgcatttta ttacataaca tccaattaaa gtattaaatc ttataagtaa atcaatattt
    48721 catcaaaata aatatagtat gctatatata gttaaatccg tatatataca aataaacccc
    48781 taatttagaa taatttagaa aatctaatat attataaatt aggggtaaat atttacttat
    48841 cttttcttta ttcctattac tttagcttga ccttctatac tcggagtcgt ttcttttttt
    48901 atttctttta cttccttaat aactttttct ttttttgttt ttttagaagt tgacttttgt
    48961 gttgaattgt atactttcat tatctcatca tatataaggt ctatggcttc aggcttacct
    49021 atagttttac ttgcatttgc catgtcaacc aaaagttctc tatcccctaa aagtttaaat
    49081 actgctgtat ttaggctctc tggagttaga tttttttcta aaatagcaat tcccgcgcct
    49141 tgtttttcta tactcttggc attatactct tgatgatttt cagcagtata agctttaggt
    49201 attattatag atggctttcc aagagctgtt atctcagcta atgaaattgc tcctgcacta
    49261 cctataacta aatcacttgc tgcaagtgca tttgccatat cttctaagta aggtacaacc
    49321 ttttgatatg gtttaagatt tatatcgcta atactttcca taaattcatc ataatagctt
    49381 ttgcctgtag caaatataaa agctatatct tcatttacca tattctttat tacaagtctc
    49441 attgcatcat ttatttttct tgaacctcca ctaccaccat agcaaagtac cattcttttt
    49501 tcttcactta ttgatagatt ttttcttgca atattttttc ttgataataa aatttctttt
    49561 ctaactgggt ttcctgtaaa aactaatttt tcttctgctg cctcaggaaa tcttttatgt
    49621 gaatcttcaa aacttgtaag tacctttgta actgttttag ataaaatctt attagttaca
    49681 ccaggaaaag aattttgctc atgtattatg gctggtattt tccccataga tgcattaaat
    49741 aaaacaggtc cactaacata accaccagtt cctataacta catctggctt aaatttctta
    49801 acaatctttc ttgattgctc caaaccttta aaaagcttaa aaactctttt tacattatcg
    49861 aaatctattt ttcgcttaaa gccttgaact gttacagtct ttaattcaaa tccatactta
    49921 ggaactattt ctgactctat tcctttttcc gtcccaacaa aaattatctc ggcgtctgga
    49981 tgctcatctc ttattttgtt cgcaatagct atagctggat acacgtgccc tccagttcca
    50041 ccgcctgata ataaaacttt catcaaatca tcatctcctg ttaattaatt ttgacatgct
    50101 ttgagatgtt taacactatt cctacagctc ccataaagat ggtgagtgaa gttcctccat
    50161 aacttataaa tggtagtgct acacctgtag ctggcattga tgatgttgca actgctatat
    50221 ttaaagctgc ttgtattcca atttgtgcac ctatacctat aacaaccata caagcaaata
    50281 cattagaagt tttcaatgct attcttacac atctgtagac taaaactaca aacagcataa
    50341 taactattat acaaccaatc aatcctaact cttctcctat tatagcaaat ataaagtcat
    50401 tttgcggctc tggtatataa aaatactttt gtttactctt tcctaagcct agaccaaaca
    50461 atccacctga acctagtgca tatagacctt gtattacctg atacccctta ccaagagggt
    50521 cttgaaaagg gtctaaaaat gatgtaacac gactaagtct atatggttca gcaattacta
    50581 atgcagcaaa taaagcaacc ccactcccta tcatagcaaa tacaattttc atatccattc
    50641 cagcaacaaa tatcatcaca aaagtaacta gaattacagt acctgctgtt gacaaatttg
    50701 gctgaagtat tatcaacgca aaaaatatac ctggaactac tagaagtggt acaacacctt
    50761 ttgtcaaaga ttttatttta tcataatttc tttcaattaa ttttgcagtt aatattattg
    50821 tagcaaactt tgcgatttct gcaggttgaa atgttaaagc ccctattccc aaccatcttt
    50881 ttgctccatt tgcttctatc cctaaagggg tcaaaactaa caataataat actactgcta
    50941 tagctccaat tgctgtagca tttttcttcc aaaaactata atctattctc gatgtaataa
    51001 tcataactat aaatccaagc acagcatata ttacattctt ttttagaaaa tagtacgcat
    51061 cattatgttt aaatgaagat tgtataaaac ttgcactaaa caccataact attcctacaa
    51121 atactaaaag catagtagta taaaatacta ctccatcaaa ttcagtcttc atccttatgt
    51181 caatttgttt tttcaaattt tctttaggca tccaactaat ctacctccat tcttccattt
    51241 aagtaagttt agaggtaaga gattatttta aattgtttac attatctttg aagtcttttc
    51301 ctcttacttc aaaactttca tacatatccc aacttgcaca agctggtgaa agaagcacta
    51361 tatctccgct ttttgaaatt tcataagaag tcttaactgc ttcttccata tcttttacta
    51421 tatgtatgtc attaaatcct ttatttttag cacaattttc tatatttgat gcagtttctc
    51481 ctaatagaac caatgattta acatatgact ttgcagtttc aagaagttca tcaaaattac
    51541 ttcccttatc catccctcct gctataagta ttataggtct atcgtaagac tgtatagctt
    51601 ttatagtaga atctggatta gttccttttg aatcattaac atatattaca ttatctaaat
    51661 ttcttacaaa ctcttgtctg tgttccactc ctttaaatgt cataagtaca tcctttataa
    51721 cctctaagtc aattttgcat acatatgcta ttgctatagc tgccatacag ttttctaagt
    51781 tatgacctcc aggtaaactt acatcatctt tatttagaaa tttgatttta tcatctatat
    51841 ctattattat gtcattattt tctaaatata ctcctccatt tactttttta gttcttgaaa
    51901 agtaaattac tttagcattg catttatcag ctagaccttt tactatctca tcatcataat
    51961 ttaatacaca gaaatcctca gaagtttgat tcataaatat atttgtcttt gcttctatat
    52021 acttttccat agtatgatgt ctatttaagt ggtcttctgt aatatttaat atggcactta
    52081 ctttaggtct aaattcatct atactttcaa gctgaaaact acttaattca gttactagca
    52141 cagattcttc atttgaagtt tctatagtat ctatcacagg atttcctata ttaccaacta
    52201 catatgtatc tcgttttgct cttgaaaaaa tttctcctac caaactagtt gtagttgttt
    52261 ttccatttgt acctgtaatt cctataaaaa ttggattatt tgatagttta aaagctaatt
    52321 ctacctcacc aattatatac ttgcctgaat tttttaattt caatatgaat ggtaggtcta
    52381 gtggtacacc tggagacact acaaccatat ctatatcatc tatatcttct ggatgatgtc
    52441 ctaatatgta ttttatatca tttatagatt ttaattcatc aagtatattt ctcaatttat
    52501 tttcatcttt gatatcattt actattatac ttgcacccaa tttatctaaa tgtttaattg
    52561 tagatatacc agtttttgca agtcctacta ataaaacttt ttttcctttt aaatccattt
    52621 tttattcccc ccagccctag aatactgcta ttatacttat ccaagccaaa acaactgtaa
    52681 caatccaaaa aataaataca actcttgttt ctggccaacc acactgttca aaatggtggt
    52741 gtattggagc catcttaaag aatctctttc ttgttgcttt aaaatatcca acttgaatca
    52801 aaactgatag agcctctgca aaataaattc ctccaattat aggtattata agcactgagt
    52861 tagttagaac tgaaaatgct acaactgcac ctcctaatgc cattgaacct gtatccccca
    52921 taaacactct agctggatat gaattaaatc ctaaaaaacc taaacatgct ccaacagttg
    52981 ctgctgctaa aactgcgact tctgtatttc cagcaataga acttgcaaat agcataaaga
    53041 atacagaaac tattaatgtt actcctgatg ctaatccatc taatccatca gtcaaattta
    53101 cagcatttac tattgctaca attataaaca tcattattgg tatatataat attccaacat
    53161 ttattacaaa atctgtaaat ggtatcataa gttgtgaagc acttgatgat gatgtatatt
    53221 gataaaaagc aacataaaaa gataatgcaa cttgaaggat tattttttga tatgctttta
    53281 gtccaagtga tctttttagc tttattttta taaagtcatc taaaaaacca ataaaaccaa
    53341 aacctgcaat acatataaga cctactgcca tatcatgact aacttttact cttgtaagtc
    53401 cagttattaa aattgcaaca atcattataa ttccacccat agtaggtgtt ccgtttttag
    53461 ctagatgtgt ttgaggtcca tcatctctaa ctgtctgacc aaatttaaat tttctaagca
    53521 ttggtataaa tattggtcct attataatta ctattaaaaa cgcaatcaat gcggtgtacg
    53581 taagctctgt tattcctaac atcataaaac tcctctccct tgtcaattaa ctctcattag
    53641 tttaagctta tttatttaga tattcgacta ttttttctaa tctcatgcct cttgagcctt
    53701 ttactaaaat agtgtctcct gtttttacta attcatttaa cttgttaaat acatcttctc
    53761 tattctcaaa gtgatatata ttggctgaat tgaatcctaa ttgttttgct tcttctccaa
    53821 taaacactga attttcacct atagttatta taatatcagt attattcata gatgattttc
    53881 caactaatct atgaccatac tctgaaattt cacccatttc tagtatatct ccaagtattg
    53941 ctactcttct acctttatat cttccaagta tctttaaagc agcatccata gaatctggac
    54001 tagcattata tgaatcatta attattgtta atttttcatt ttttattatg tctagtctca
    54061 tttttgtccc tttaaaattt ttcaaacctt tttttatata atctaaagaa atatttagac
    54121 ataaaccaac taatatagca gacattgcat tatatatatt atgttctcct attgttggta
    54181 taaatatttc ctcttttttc ccatttatta cacatataaa tgttaaacta tcctcttcca
    54241 tagtataact ttcacaataa atatcattat ttttattaaa gccaaatgtt tttaacttat
    54301 atacatgttc tttttccttt aatgtagata aaaacttatc atctccattt acaattaaag
    54361 tatttgcttc atcaaagttt gaagtaatct ccatctttgc tttcaaaatc ccctcttgtg
    54421 aacctaattt ttctacatgt gataatccta tattcgatat gactgcgatt ttaggattta
    54481 ctatatccac taaatatttt atttcattga atccagacat acccatttct attacagcac
    54541 actcatgttc tttacttaga ttaaataaag tcaatggaac tccaaaatga ttatttaagt
    54601 ttttttcatt ttttagtata tttagctttg cagatattgc agaataaatc atatccctag
    54661 tagtagtttt tcccacacta cctgtaacac ctataaacgg aatatcaaat ttttctttat
    54721 agtattttga aatatttcct agagccaaag atgtatcttt tacctctatt aaatttatat
    54781 ccgaactttc taattttatt ccattacttt cattttttat aaaagtttta catccactat
    54841 catatgcaga cttcataaat gtatgcccat ctaaattttc tccaactatg gctacaaatg
    54901 cattttgggc atttgcctcc ctgctatcta taactatatc acttacacag tcattataat
    54961 ctccatatat taacttccca ttagttgcaa gtactaactc ttttattgtt aagcactcca
    55021 ttatcaaact cctcctttaa aaccttagct atattctctt agcaacaaaa ggcaatgtat
    55081 accgttatat atacattgcc tacgataact cttaacttta taattatata ctatatttct
    55141 gtttttttga agatgtttat gggtatatgt taattatctg ttacttttta gttttcaaaa
    55201 tatagggtta tacttgagtc ttcattaact tttactccag gttttgggaa tatatccttt
    55261 acctttgtat cttctggaag ttctatatct gcatctaagt ctggttttaa cttcacatcc
    55321 tccaatgcct ttacagcatc tcctattttt agatttctta catctggcac tttaacttgc
    55381 ttcttctcat actcagcttt ttcttcttct ttgtatactg gtttaactcc taaatatttt
    55441 aaagaatcat tcattatttc tttcactatt ggtcctgctg tagtactacc aaatgcgctt
    55501 actcctgttg gttcgtcaac aatagcaaga actactattt gtgggtcatc acaaggtgct
    55561 attccaacaa atgaacatat atattttcct ggagcatact taccatctat aactttttga
    55621 gctgtacctg ttttaccacc aagtctatac cctggtatat atgctatctt tcctccacct
    55681 tcagttacaa ctgattctgc aatttctaac atttttttag atgtttcttt agatataaca
    55741 cttcttactt tttttggttt tactgtttca gttatatttc ctttattgtc agtataagat
    55801 tttaccactc ttggttgcat taaatctcca ccattagcta ttgatgatat agctgttata
    55861 agttgtattg gagttactga tatagattga ccaaatgata ttgtagccaa ttcaactggt
    55921 cctacatttt tttcgttata caatattccc ttagcttctc ctggtaaatc tatacctgtc
    55981 ttatccataa gaccaaatga ttctatataa tcatacattt tcccaacacc taatctgctt
    56041 cctaactcaa caaatactgg gttacaagaa ttttgtactg cttgtttaaa ctcttgtgtt
    56101 ccatgaggtc tgtaatgtct ccaacattta atctttcttc ctccaacagt tacactacct
    56161 gtacatgtga atttttctcc atctttaatt actccttctt caagagcact ggaagatgta
    56221 ataagcttaa atgtagaacc tggttcatat gtatcactta ctgccggatt tctccacatt
    56281 tgataatatc cttttatttt atctttatca ttatattttt caagttcttc ttgataatat
    56341 ggatatattg gtgttcttga atcattaggg tcataatctg gttttgatgc taaagcaagt
    56401 atatcaccag ttttagggtt catagctatt gcagtaacct tttttgcatt atttaactca
    56461 tacgctttct gtactgcttt ttcagtatag tgttgaatta cttcatctat agacaacaca
    56521 agaccattac cttgtacagg ctcataatat ttttccattc cctgtggtat ttctcttcct
    56581 gaggcatcag tacttactat aagctttcca ggctttcctt ttaatttttt atcatattgc
    56641 atttctatac cagatatacc tgttgcatct gaagaagtat gtcccaacac atatggtgca
    56701 aaattcccat atgggtaata tctttgatta tcttctgcta cccatattcc acttaattta
    56761 gcatctctta ttttacttgc cttatcatca tctatccatc tttttacttt tacaagagcc
    56821 atattttttt tacttattaa agcataaata tctttataat cttcatccaa aatctcagct
    56881 accttttcgg cggcttcctt tttatcttct acttccacag gtttacacca aacagtatac
    56941 ttagttacac ttactgctaa ctctttcata tttctatcat atatagttcc tcttttgggt
    57001 tctattggta tatctcttgt ttgctgttct agagcttttg tacttaacca atttcccttc
    57061 ataagttgta gatacccagt cctaataaca aggcaaaaaa ataatgcgca tgctagaata
    57121 agaacgagta ccagcctttt cttacttatc ctctttactt ttctcaaatc tattccccct
    57181 agttatccac atctatatac tttatttgtc catcttttgg atagtccata ttgagcaatt
    57241 ccttagcctt tagctcaatt tcttttatcg atgttttttc agtttctttt gcctttagtt
    57301 cctctaatac tatctctttt tttcttaaat ctttttgtaa ataataaata tcgtacttca
    57361 tttctgagat ttttgaataa ccacatagat tcaatattat tactgcaaaa gttgcaatca
    57421 gtaaaatgca tttagttcct atttttttct tatttctctt tttataatta ttcttttttt
    57481 tatttttata ttcatttaga ttatgtattt tataattttt tttcaaatta tcacctcgat
    57541 agtatatagt ttaaattttc ctctatacta tatttgttgt taatcatatt tcttcctcta
    57601 aaatttcatc gctaaattaa tacactattg cacaatctaa ttgtgttttt ttctatacac
    57661 aacaaaaacc tataaattca cttatacttt tatatgaatc tataggttag atattaattt
    57721 ttatttattt ttatcacttc taatattttc agataatttc ttccataaat ataatatgta
    57781 actaactatc tactttctaa tttctccatt atattactta atatcatcta tatctatatt
    57841 tttataccta aattttcatt atatatctca ttagcaaaaa acatttctta tagtgttaat
    57901 tattttgtaa ttactttacc agtgcaacaa aatatacgat actttttaat taattataac
    57961 aaatcttatt ttatacataa gattactctt taactttata aattatattt tttctgctac
    58021 tcttagctta gcacttcttg aacgtggatt tgcttctact tcttcctcac taggtaatat
    58081 aggttttcta gttattattt ttacctcaga ttctttgtca cattggcata taggtaaatg
    58141 ttgtggacat atgcaatctg atgctagata cttaaatgca tttttcacta ttctatcttc
    58201 taatgaatga aatgttatta tacatattct tccaccttca ttcattatag aagaagcatc
    58261 atttatcatc tttgtaatta ctccaagttc attattcact tctattcgta ttgcctgaaa
    58321 agttctttta gctgggtgag gaccatctat tctggctttt ttagggatag cttttttaat
    58381 tatatctact aactctcctg tagtttctat tgttttgttt gctctttctt caactataaa
    58441 tttagctata cgtttagccc agttgtcttc accataatct tttattatct tagttaattc
    58501 atcttctgtg taagtattta caacgtcata tgcagaaaac tcacacctaa catccattct
    58561 catatcgagt ggtgcatctt gcatataaga aaatcctcta tcagcttcat caagttgatg
    58621 agatgaaact cctaaatcag ctaatacacc atcaatcttg taaactccta ttttttctaa
    58681 ctcctctttt atattttcaa aattgctatg aacaaacttc actctacctt catattcact
    58741 caatctctct tttgctgtgt ttatagcatt tttatcttgg tcaaacccta taaataatcc
    58801 cttatctgaa agttttttta ctatttcctt agaatgtcct gctcctccca tagtacagtc
    58861 aacatacact ccatctggct ttatatttaa attctctata cactcattta aaagaactga
    58921 tacatgatga aattccatag ttacctccct taaattcact ttttaaacta ttcttcacta
    58981 atattgtttt tatttttctt tgataaataa atatgtgcaa ttagaccacc aataactcca
    59041 attagactta taacttgtgc cattctaagt ggacctaaca ttaaactgtc tgttcttaat
    59101 ccctctataa aaaaccttcc tattgaatat aaagttatat aagtaactat aacttgacct
    59161 tcatattttt tattttttct aaatagtaat aaaactataa atattccaaa gtcccatatg
    59221 gattcataca aaaaagttgg gtgtaccttt actccatcaa ccattattcc ccaaggtaaa
    59281 ttagtagcac ctccatgtgc ttctccatta ataaaatttc cccatcttcc aatagcttgt
    59341 gctaagggca ttccaagtat aactgtatca gccattttta agaagttaat atttttaatc
    59401 ttagtgtata tataaccagc taatattcca ccaattaacc ctccatgtat agcaagtcca
    59461 ccacctctaa aattaaaaat ttgagacata ttttgagcat agtaactcca attgaataca
    59521 acataataga ttcttgcaca gattaatcca gctggaattg ctattatagc tatatttaat
    59581 acatcatctt ctttaattcc cactcttttt gattctttta ttgctattag agttcctaaa
    59641 atcataccac atgccataag tattccatac cacatgatgt ctatgccaaa cagtgtaaat
    59701 gctactctat ccataacgtc acctcttttt attaattaaa aatatttcca aagaaatatc
    59761 ctataattac aattaattgt aattatacta aattatgata acacattaat gttaattcta
    59821 caaaaaatat taaaatttat tctatagata cctatactat attataccaa tctaattgat
    59881 ataaaattct ttgaactgaa cctcacatga ctaaaatcac aagtgtgcat agatattttt
    59941 taatcaaaaa gattgatgta tgtatacacc aatcttttat atatcttatc tataactctt
    60001 aaatttttta actcaacttc tataaagata tttcataaat ttgttttact aaaataaaca
    60061 ttcaaaaaca taaactaaca tttaactatt tattcttatt atgattaaat ttctatttag
    60121 gctctacaat agaaataaca caatactcct ctttaaaatg ttcttttaat ctttcttcaa
    60181 cttcctcaaa agtaatatct ttaataacat ctaaataatc caataaattt atatccttaa
    60241 acacataaga tataaaacta tttcctataa agtttataga atcaaagcac ttaataaatg
    60301 aacctatttt tttcttttta gttctatcaa actcttcttt tgataagccc tctttttttg
    60361 atttttctat ataatcaaga attatttttt ttactttttt aggttcttta gaatctcctg
    60421 ctattatgct aaaagcataa tctacttgag atgaaaatcc agctccaaaa ttgtcattta
    60481 ttaaaccttg catatataaa tcttcataaa gcttacttcc ttttttaaat aacattccta
    60541 caagtatatc agttacaatc tctttacgta aaagttcttt tccttttaaa ccaacattac
    60601 tatctttaaa acctatgttg aacataggca tagatatagg gaatttttct atgacctctt
    60661 tttcttttac actttttggt tcttctggat aaaacctttc tatactctta gagagtttat
    60721 ctactttgta attgtttgat tttttagtta catctataac tttttctaca tctaggtcac
    60781 caacaacaaa tagagccata tttcctggat tataaaaagt gttgtaacat ttatataact
    60841 cttctttagt tattttatat atactatcga ctgtacctgc tatatcaatt ctagcaggat
    60901 aatttacata cattgccttt aaacaattaa agtatacatt ccaatcaggg tcatcattat
    60961 acatttttat ctcttgtgct attatacctt tttccttttc aacattttcg tctgtaaaat
    61021 aaggtgtttg aacatagtca attagatgtt ctaaactctc ataaaaattt tcagtagcag
    61081 aaaataagta tgctgtcatt gtaaaattag taaatgcatt tgcatttact cctaatttag
    61141 aaaatttatc aaatgcatct cctccatcag gttgctcaaa catcttatgc tctagaaaat
    61201 gtgcaatacc ttcattcact ctaatttttt tatcttctcc aagtggtaca aactctaaat
    61261 cattcgaacc ataattagta gccaaaatgg catacttttt cataaaaccc cttttaggca
    61321 taaaatatac atctaatcca ttttgcaatt tctcataata aacttcttct ttcaatatat
    61381 cattaactat tttttccata gacatctcct ccattaattt ctcaagaagt atacagtatc
    61441 aagttctata ttttttatag cttcaactat atcttttttt gtaacctttt ctatactaga
    61501 tattatgtct tgtacttcag aatttgtctt tgccatagac tgagagaaag caaagtcaga
    61561 cataccacct atattatcag ttatagattt catagaatta actaaagcaa gtttactgtt
    61621 ttctaattct tcatcagata tgtcacctgc ttttacactt tctacttgtt cttttatcaa
    61681 ttccacggct ttatcataat ctttagtttc tataccagat gatataaaca ggatactttt
    61741 atacttctct attgaagaga atatatagta acataaactt tctttttctc ttacattaac
    61801 aaataattta gagtgtggac caccacctaa tacattgctt ccaactacta aagcataata
    61861 tctatctgta tctgcataat ccacatttgc tctataaccc ataactaact taccttgagt
    61921 tatttccatt tgttcatcta caacctttac ctcatcaaca ttttttataa aatctgctct
    61981 tggtatatct ataatttctt ctctttcaaa ttttagattt ttacttatta tatctacaac
    62041 tttatcttca tcaaaattac cttctacaac tatatctata ggtgatgttt taagtatgtt
    62101 tttataatgt tcatataact cttttgaagt tatactatct atttcatctt cataaccaaa
    62161 ttcacttata ctatatctct cacctttaca catagcctca atacatttat cttgtgcata
    62221 ttccttttta tcatttatta ttgattgtat cttttctctt aaattctctt tttcaatatt
    62281 taaatattct tctttaaatc cgccatctac aacaagcgta ttatttatca cttcattaaa
    62341 aaattctact acttcttcaa atatactctc atctaaatac ttttcactta tgttaattac
    62401 tttaaaactc aatacttgac gttctccacg ttttacagca tcagctccca tagatgaacc
    62461 atataaatca tctaatttat tggatattgc tctagcacta ggatatttgg cgcttccact
    62521 tgctattatt gatggtatta gagcattttt tgtagtttct ttttcatcca atagtctctg
    62581 aacatataaa cttataagat tcgatttaaa cttttctgtt tttatcaaag taagattaat
    62641 attattacct aaatttatta tttttttagt attaaccata tgtacctcct atttttattt
    62701 aaacatcaat tttaaaattg aaatttattt attttttaat ttcatatact cacatataaa
    62761 aaccttctat ttaattatat cctttttatt attttctaaa agcaatattt ttatttaaat
    62821 taaatacaaa tattatttaa atcaatatga tttaaagtct agtttacaag cttgatatat
    62881 atgatgtata atcaatatgt atgtctataa ttaaaacaat tttacaatcc tatagattga
    62941 ttgtttaaag ttatataaag aatataaaaa agaataagag agaggacgat taatatgaaa
    63001 ttaggtatag ttggtttacc aaatgtaggt aaaagcacac tatttaacgc aataactcaa
    63061 gcaggtgcag aatctgcaaa ttaccctttt tgtacaatag acccaaatgt aggagttgta
    63121 tctgttccag atgaaagatt gaacaaacta caagaattat ataattctga aaaaatagtt
    63181 cctactgcta tagaattttg tgatatagca ggtttagtta gaggtgcttc taaaggagaa
    63241 ggtctaggaa ataaattctt atcacatata agagaagttg atgcaatagt tcatgttgtt
    63301 agatgttttg aggatgaaaa tgtcgtacat gtagatggtt ctgtagaccc acttcgcgat
    63361 atagaaacta taaacttaga attaattttc tcggatatag agattcttga aagaagaatt
    63421 aataaaactc aaaaagctgc caaagctgat aaaactttag gttctgaact tgatttatta
    63481 aaatcaataa tgtctacttt agaagaaagt aagtgtgtaa gaactatgga atttacagaa
    63541 gatgaacaaa tattcgtaaa ttcattggat ttacttacat ctaagcctgt aatatatgct
    63601 tcaaatgtat cagaagatga tttagctgat aatggagaaa ataataaata tgttcaacaa
    63661 gttaaagcat ttgcagaaac agaagatgct gaagttgttg tagtatgtgc acaaatagaa
    63721 gcagaaattt ctgaacttga ttctgctgaa gaaaagaaag agtttttaga gacattaggt
    63781 cttgaacaat cagggcttga taaacttata aaatcttctt atgctttact tggtttaatt
    63841 tcattcttaa ctgctggtcc aaaagaagtt agagcatgga ctataaaagt tggaagtaaa
    63901 gctcctcagg caggaggaaa aatacattct gatatagaaa gaggatttat cagagcagaa
    63961 acaatagcct ttaatgattt agttgagcat ggtactatgg ctgctgctaa agaaaaaggg
    64021 ttagttaaat tagaaggtaa agaatacata gttaaagatg gagatgtaat attatttaga
    64081 tttaatgttt aagatgatta aacatataca ttttgactat tatatgtatg ataattagaa
    64141 aattaaactt attgatagat tttttattat ctctgtataa ttatgtaaaa ttttttaaaa
    64201 gagagatatt ctaaatgatt attataaatc atttagaata tctctctttt ttacatagac
    64261 ggtttctaaa taacccactt ttggtctatt ctttgcagga aaaatcttat aagaagccat
    64321 tccaacaata tgaccagcca ctatatcaag aaaagcatct ttaggttttt taatgccaaa
    64381 ctccctacca atccaaaact taatttacca agttcttaca caaaccttcc tttgtcatcc
    64441 gccatttttc taattttata caagttatcc ctcccaagtt tttaaataat ttttgatata
    64501 cttaattgta taaactctac agttaatata aagttttata tcagaatact tcatatactt
    64561 taaacaaata tcatctaact tgtaacttgt tattcctaac aatttatatt cttaataata
    64621 gtacattttt ataaaaaaag tgaacattga ttaaacaaag ttcacttttt ttaattttta
    64681 tatggtattt cataagttta tctaatttat ttcttttccc tttacactgt atctatctaa
    64741 tattaatttt tcatattctt ctattggcat tggtctagca aacaaaaacc cttgagccat
    64801 atcacaacct ataagcctta aaaactctgc ttgctccaca gtttcaacac cttctgaaac
    64861 aacttttata tcaagttgtt ttgccatttg aacaatactt gaaactacaa tttgactctt
    64921 ttttgcattt cctactgtta taaagaattg cctatctaat ttcaatacat caattggcat
    64981 atctttaagc atatttaaag aagaataacc agaaccaaaa tcatccatag aaattttaaa
    65041 tccaacagat ttcaaagttt gcattatttt aaataatatt tttgtgttgt caaatattgc
    65101 actttctgtc aattcaatct caattaaatt tggctcaatt tcatattctt ttgttattct
    65161 ttcaagctca gaaataaaat ctggattctc aagatgtact cttgataagt ttattgatat
    65221 aggaaatgtg gggaaatttt cattttccca acgtttaaaa tttttacaaa cttgtgtaaa
    65281 tacaaacata tccaattctg ttataaaacc atttttctca aaaataggaa taaatatacc
    65341 tgggcttatt agaccttttt ttggatgttg ccaacgtaca agcgcttcag cgcctacaat
    65401 tttagtagtt gataaatcaa ctttaggttg taaataaact ttaaattgtt cattttttaa
    65461 agcatcatgc atttcttgtt caatatcacg ttcttctatg agaatttctt ttaaattttc
    65521 agcataaatc tcataaactt ttaaatattt tctttttaca gcagtttttg caatcatagc
    65581 tttgtcaaga caggtagaaa tattggtttc tccctcttca acaaaataca cacctataga
    65641 tggaattaaa ttgagttcta ctcccaaact tgtttttatc attgacaatt ttttacgtat
    65701 aagttcacat atttctataa ttgatgctct attatttttc ttttcaaata ttatagcaaa
    65761 gttatcattt gaaattcttg aaaatacaga ttgctcttta aatatattct taattatctc
    65821 tgctatttcc tttaatactc tatctccttc ttcgtaccca aacctatcat ttactagttt
    65881 aaacttatct atatcaaaat aaattaaaac tagattcttt ttctcatgag aggataaaaa
    65941 ttttccccct tcaagattaa atttatttga attaccaatg cctgtaacgt tatctttaaa
    66001 ggcaaattct tctaattttt ccttactctt tttatgtata aatagtatat aaattgttaa
    66061 tgctgtaaag attataatca acactacaca tgctgataat gtaagtttta taatagcgta
    66121 tgatttctca gatatagcag ctttaggaac ttcagaaaaa agataccaat cattgattcc
    66181 tattggagca taacttaaat aatatcctct tccagacata ctataactta atgaacctga
    66241 tttaaagttt tttatatttg acttcatatt attgatacta gattttgata ttgaatcact
    66301 tttaccaatg taagaaaata aattttcttt agtagagttg gcgtttttac tacttggatt
    66361 taaaacaata tcaccattac ttctagctac ataagaatat ccttttccat taaatgtagg
    66421 tacagaaagt attttttcat acaacttcgt actatgtgta gcaaatataa ctcctttaac
    66481 atcattattt ttataaattg gtacagagta tacattaata tcgctattgg tatttttatc
    66541 atcttctatt acatctttca actttcctgt tataaccact tctccttgca ttgattttaa
    66601 gaaataatct cttttagaga agtcttctct ataaccatct gtagtgtatg ctgtaccatt
    66661 tggtaaaata acgcccattc ttttaaatga actattaata gcttgttttt tcagtataga
    66721 aaggatatta tctacttcaa aatactcttc tccttcaata aatattgaaa tggactctag
    66781 taactttata tctccattaa tttgtttttt taacacattg acgctttgat ttgctatttc
    66841 tgaaagatat tgattcgttt cttcacctaa tgtcttattc aaccttgaac cataaatcaa
    66901 acaggaaatt gtaattacta agatacttat gacagcaatt atggacaaac catacctatt
    66961 attttttgca tcacttaaca ttatgcttcc tgcctttctc aaatctatgt atgtataatc
    67021 attatcttat gacaattatt gtaaacattt tataataata cttatttttc catatttact
    67081 gtaattatac aaaattataa actttattac aacaataaat taattaatgt agatattagg
    67141 gtttatatta ttgcattatc tatttacaat catttacata taaaaaatgt aatatcaaag
    67201 taaaacttga tattacattt ttgttcttgt attttgttta ctttttatgc tacattttac
    67261 ttaaacactc attggcaact tctttatcat caaagtgatg cttaacttta cctataattt
    67321 gataagtttc atgcccctta cctgttataa ttacaacatc atcctttttt gccatactta
    67381 tagcttctga tatagcttgt tctctatcaa caacaacatg gtaattttct tttttcttgt
    67441 caattccttc aagtatatct tttattattg cttctggttc ttcagttctt gggttatcag
    67501 aagttataat gcataaatca gaatattttt gtccaattgc tcccatcaaa ggtctctttt
    67561 cagtatctct atctccacca catccaaata cagaaattat ttttccttct gcaaattgtt
    67621 gagttgtttt tagtacattt tcaagtgcat caggagtatg agcatagtct acaattacac
    67681 ttataccttt atcatttgga actgtttcaa accttccgga tactccatta gaaagtctaa
    67741 gaccttcttt atatattggt ttgggtatgc caagtacata gcaagcagct ataactgcta
    67801 aagtattata tactgtaaac attcctggaa ctggtataaa tattacttct tcatatgaag
    67861 gtgttattaa tctataagat actccatccg aatctgattt tatatctcta gccataaaat
    67921 cagcattagt atcaacccca taagtgtaac aaggtacatt tatacctttt atattttcat
    67981 atatcttttt tccaccttca tcatctatgt ttattatatt tgccatagta gttttaaaaa
    68041 ataatttttc ttttgctttt ctataatcct ctaaatcttt atgaaaatct aaatggtctg
    68101 gtgttaaatt tgtaaatatg cctagtttaa aatctgtttc atcaactcta tttaatgcca
    68161 atgaatgtga tgaaacttcc atcgcacagt agtcacatcc attatccaac atattattaa
    68221 aatgatattg taaatctata ctttctggag ttgttgaatt ggaaacaatg tctttttctc
    68281 cgtcaaaaat ttttatagta cctataagcc caactttatt cttatttaaa gttaatatct
    68341 catttagtat ggtagttata ctagtttttc cattagtacc tgtaactcct ataacgttaa
    68401 atttttgaga tggatgattg taaaaattat cagctacttt tgccatatct tttcttgtat
    68461 cttttacctt tataaatgta catcctttta tttctacatc ttcttcaaca agaaaggcac
    68521 ttgctccctt ttcaatagca tcttttatat acttatgacc atctgacacg aatcctttta
    68581 tacatataaa taatgtacct tttgtaacct ttcttgaatc atattgtaca ttattaatat
    68641 ctatatttaa ttcacccttg acattgatta tatccaaccc ctgtataata tcatttaatt
    68701 tcataaatgc tttcctccct ttaaactctt tctgctaaaa ttacactaca tataatatta
    68761 tattaagaat tttttactat gtgaatggtt aaaaatgctt gaaacattgc aaaaaatgct
    68821 ctataatttt ctataatata actgaagaaa ggtcttctat aaaaactatg gataataaaa
    68881 tcgggtactt aaatgataat tttaaaatat ttaatattag agataaaaaa aatatacaat
    68941 ttgaatacca taatcatgat tttaataaga taattatatt tataaatgga aatgtaactt
    69001 attttgttga gggtattcct tataaactaa agccttggga tatattattt atcagcaata
    69061 atgaaatcca taaaccagtt atagattcaa atgtctttta tgagagaatt gcaatatgga
    69121 ttagcccaga atttatgaaa aaaaatagtg atgctactag cgacttagaa aagtgtttta
    69181 aaatatctac agagaataaa tgtaatagat tgcgtttaaa tatgcatgat attgaatcta
    69241 taaagagttt tattgagcaa ataaatattt ctgaatccaa tactgaattt ggaaatgaaa
    69301 tattgagaaa tgcattattt atacaactta tgatattctt aaacagaatt ttcctaaaaa
    69361 acgaaaatat agaatcaaca gaagacgttt tttatgatga aactattaag aaagtattag
    69421 actatataaa ttcaaacata gatgataaac tttcaataga tagtatatcg tctgaatttt
    69481 ttataagcaa gtattatctt atgagaaaat ttaaatctca tactggaacg tctatacaca
    69541 actatatagt tcaaaaaaga ttgattttgg caaagtcatt aataaccaat ggtcacctta
    69601 tgagtgaagt ttgtaataaa tgtggattca acgattattc tagctttgta agggcgttta
    69661 aaaaaaacta tggtgtatct cctaaaaatt atataaacag taaaaaccct ttagacatta
    69721 ctcttttaga tgaatagata atttatgtaa attttatttt gataaaaact tgaggtgtta
    69781 gtatatttat cttactagta cctcaagttt tttaattttt taaaatatat caaaatataa
    69841 tgatatatat ttctattact taaaatatat actaactaaa ttggatgtta acttaaccta
    69901 tttatgtgtt cattaaatct catgtaactt ttagttatac tatcatatag ctatcctatt
    69961 ttttcaatat cgtctcttaa tataattact ctattctcct cttttgctgt agttattcct
    70021 tttttaatgc ttaatttctg attttgttct aaattcgtaa atactacagg gcttattgtt
    70081 gatagaccat ttttttcaat atattctaag tccattttaa ctaatttttc tcctgctttt
    70141 acttcatctc ctacattcac aaatacttca aatccatttc cttctaagtt tacagtttct
    70201 atccctaaat gtataagtat ttctactcca ctttttttgg attttattat tattgcatgc
    70261 ttagttggaa atataactcc aatagttcca tcaactgggg aataaatcaa cccatcatta
    70321 gatttaattg caaatccatc ccccatcaat ttacttgaaa atacagaatc tggcacttct
    70381 tctatatcta atatctctcc atttgttaat gaataaatat tttctactaa agcattttcc
    70441 atattggcaa cttccatatt ttttttcatt ttatttttat cgttattttt aataacagca
    70501 ctttcaatct ttgtttttcc ctctattata tcttttatat cagactttat tgaatccgat
    70561 tttggtccaa atataacttg cacattgttg ccaataacca taacacctgc tgctccaagt
    70621 gatttcaatt tttctttatc tactttattt atatcattta caatcaatct aagtcttgtt
    70681 atacacgcat ctagactctt taagttttct ttatttccta aagcaaccaa aatctctgat
    70741 gctaattcat tcttagacat atcaatgact tcaacattag tttctgaatc atcttctctt
    70801 cctggtgtct ttaaattaaa ctttcttatc ataaatctaa atacactata gtataatact
    70861 gcaaaaccaa tacctaccaa aatagccaag taccatggag ttctattagg aagaacacca
    70921 aataataaga aatctattaa tcctcctgaa aatgtgaatc caattttaac tcctaataat
    70981 tgcataactg cgtatgataa accagaaaat aaacaatgta ttgcaaataa tactggtgca
    71041 acaaataaaa acgcaaactc tattggctca gttattcccg ttaaaaaaga tgttaatgct
    71101 gctgatgcca ttatacctgc tacaaatttt ttcttttctg gtttcgcttc atgcaccata
    71161 gcaagagctg ctgctggaag accaaacatc ataaatggaa atgcacctgt cataaaagta
    71221 cctgctgtga aatttacgcc atctttaagt tgagcaaaga atatcttttg gtcacccatt
    71281 acaagctcac cagctttatt tacatattct ccaaattgat accaaaatgg attatggaaa
    71341 acatgatgca aaccaaatgg tattaataat ctttctaaag aaccttccat aaatgctgct
    71401 agtgtttgat ttgcttctat aacatttttt gagaaactaa gtaatccctc ttgtattgga
    71461 ggccaaataa aagacaatat aattcctatt gctatagcaa ctaatgaagt aacgattggt
    71521 acaaatcttt tacctgcaaa aaaacctaga tactgaggta attcaatttt ataaaacttt
    71581 ttataaagat aagcagccac tatacctata ataataccac caaatactcc tgtttgaatt
    71641 gttggtattc caacaatact tgcatacata gaattatcta tcatatcttc tgtaacacct
    71701 gccataacac ccatagatgt attaagaatt aaaaaaccta ctatagctgc caatgctgca
    71761 acaccttctc cttcggtcaa accaacagct acaccaactg caaatataag tggtaagtta
    71821 ttaaatataa tttgacctga actttccatt atacttatta taagttggaa tgtagggttc
    71881 gctaaagctg gaaaatgagc caacaacgca tctcctgcta aagcattact cacgccaagt
    71941 aatatacctg ctgcaggaag taatgcaact ggtagcatta gagactttcc tactttttgt
    72001 aaaacaccaa atactttttt catttacttt tctctcctta ttattttata ttttttaaat
    72061 aaaaaagact taagtttata aaaagttaca ttagtatact taattctaaa attaaactta
    72121 ttttaatata aataaatcta tattaaccta atttcagaat taaaaataaa ctattataat
    72181 ttttttataa acataagtct tgcctgcatt atcagtaaca atcttaatgt tttaaaatta
    72241 ttgttttata ttaaatttta aataatatat taaaattaaa cataatatac taaacctata
    72301 cattttgtat taaactactc tttattataa attcaataca gatataactc ttttgatatg
    72361 taatgttaaa taaagtagtt catcttgact tacatagtaa tcataattct tttctacatg
    72421 agtttttatt ttgtatgcac aattataatc cttttcatac tttactttga ttatgtctat
    72481 aatttcatta cttgtatcat taattttttc tctttttact aaccgttttg caaagaattt
    72541 taaatgagtc agaagcctat cataatttat atcatcttct ttaaattcaa ctctataata
    72601 atatcttata atatttagta tgtcttttac aatcttagta attaacaatg attcctttga
    72661 acttccttta tagtttgaat ttactatatg cattgctata aaaccagctt catccaatgg
    72721 aaactttacc ccaaattctt tatttatgta atctacagcc cacttcccaa tctcatattc
    72781 ttttttatgt attcttttta tctcatgtag taactcattc tttataatta tattttcatg
    72841 atatctttta attgcaaatg caatatggtc agtaagtgcc acataaatat attcataaag
    72901 cttagtattc aaattctctt ctgcataagc aattatttca gtactaatcg caaaaaattt
    72961 ctcatcaacc tggcttgcta gtttaccaat tttatctaaa aagctttcat cttgtattat
    73021 aaaagttctt tcaattttat ttttatctat ttcttgacct ttcttttttt gaaacccaat
    73081 cccacatcct gttagtatta attctttttt tatattttca tctaaaacta atacgacatt
    73141 attattataa atttgttgaa taatcataat caatatctct cccaaaatac aatttccctt
    73201 attcataaaa aaatacctaa attaagatac aattcacctg tataccttaa cctaggtatt
    73261 gcctgcttac cagtaacaat ccagcctgtt aacgcttata tattgtattc aatttatggt
    73321 tttattctat tataaataaa tatatatgtc aagtaaatta ttgaaaacta tttcctattt
    73381 tttgtattaa ttctaacatc aaaaatcaaa ttttattcca ttatatttat gattctatca
    73441 tcatcatttc atcatataga atattttcca ataactcttt agccacttct cttgatattt
    73501 gcttattttc aactaattgt tggacactgt ctctttgact ttgtattgcc attactctgt
    73561 agtattctac tcttgactca aacttatcat cattttgaat ctttctagta atccaattca
    73621 aataacgatt atagaatctg attgatatta aggcctcatg tctgttattt tcatcagtat
    73681 ttttatttat aaatgatata gccgttttag tagaaagtgc atatgcatag tgaaattctt
    73741 tgattatttc tttattctca gacactattt ttgtaatttt ttcttttact tctttcttta
    73801 cttttctgtc tatagtccac atacttattt ttaattttat aattttaaat atagattttt
    73861 gaacagattt tcttgatttt gtaatataaa atctatacaa tttaaatgct ctatcagaaa
    73921 ttttaccatc ttctaatagt ttcaaaacag ccaataatcc ctgtttgtct gcttctgcaa
    73981 tcatcatact tataagttta ttatctggag tatttaatat tcctttttct gagtctacta
    74041 actgttcatt taaatcatgt ataactaatt gtgcttcttg tgctttttca ttactaagtt
    74101 ttaaaatggc ttctttcaaa attagtttat atgcctcttt atcagataat aaatgttctg
    74161 actcttgtga attacttttt aataatcttg gcagtaaaac tgttgccaat attaaactta
    74221 taagaataac ttctgatgat ataaataaaa cagtatctct cattggaaat acatctttat
    74281 tagccaaatg aaatggtata gataaggcag tagcgagtgt aaacgtacca tgaacaccac
    74341 aagtagcaac tattagtgag tatttacacc tagaaatatt ctcttttaca gcttcttcat
    74401 ccttaaaacc taaaaaacct acaaaaaaat tatttaaagg attcttttta gtttttataa
    74461 aagaatcatg ccataaatat acccatataa atcttataac aaataaaata aatacaatta
    74521 aagcagaaat aaaggtcaat ttcaatgtca tatcttcatt tttactacta agtcctgtat
    74581 atatacttgg taacagaaaa ccaagcagtg taaagacaaa cccattcaat acatactcca
    74641 aaacatacca agtgttgtct gatattatcc ttaatttagt agttgtattt tgtaaatgct
    74701 ctttttcaat tccatgagct atccctgcca tcacaacagc taggattcca gatactccta
    74761 cttcctctgc tacaaaatat ataaaaagtg gagtcattat ttgtataact attaccattg
    74821 gaatttcttc caaattccac ttatgtaggc taagtcttat ttttataatt atgtatccta
    74881 aaatacttcc tactattatt cctccaaaag ctgtaattat aaattgaatc cctgcctctt
    74941 ctattgaaaa aacgcctgta actgtggcaa gtactgcaac cttaaatgct actactccag
    75001 cagcatcatt taataaagat tctccttcaa gtatactcat catattttta ggaaaattta
    75061 atccttgtgt gattgatttt actgctacta aatcagttgg agatattact gctgccaaag
    75121 caaatgaaac agataatggc atcccaggaa taagaaaatg tataaaaatt ccacctgcaa
    75181 acacagttgt taaaactaaa ccaaatgcaa gaagcaaaat tggttttcta agttctaaca
    75241 gctcttttct tgatacattt tgagcttcac taaatagtaa tggagctata atacatatca
    75301 caaatatttc tggattaaat gaaaataaga atttaaatgg caaaatagat aatataatcc
    75361 ctaatacaat ttgatatatt gcaagaggaa tattattcca ctttttgcta aatacagttg
    75421 aaatcgttgt acaaaccaat aatcccaaca atgttactaa aattgacata actacctctc
    75481 ttttcaataa taatattata gattaaactt ctgtatcaac taacttaata ttaacaacac
    75541 gaaattccat cttcatcaaa aaattttcaa tttattctat tattcttatt atatacatta
    75601 aatttaattt ttgaaatatc tatattagat gacatgcaac aaaatgattt cttgatattt
    75661 cttttaaaac tggaacctct tttttgcata tttccttaca ataagggcat cttgtatgaa
    75721 acttacatcc acttggtgga tttgttggag atggtatgtc tccttttaat ataattctat
    75781 ttttcttaat tgtagggtct tgtacgggta ctgcactcat aagtgctttt gtatatggat
    75841 gttgagaatg taaataaagt tcttctttgg ttgcaatttc tattatagaa cctaggtaca
    75901 taacacaaac tctatgtgca atatgattta ctacactcaa atcatgagat ataaataaat
    75961 atgagagttt atatttgtcc tgtaaatcca taagtaaatt tataatttga gattgaatag
    76021 aaacatctag tgcggaaaca ggttcatcac aaactataaa ttctggattt aatgctaatg
    76081 ctcttgctat acctattctc tgtctttgac ctccagaaaa ctcacctggt tttctattta
    76141 aatggtactt agaaagacca caactttcta caatatttaa tatattatct tttatttcat
    76201 tctttggcac taaatcatgt tctataactg cctcagatat tatttgctcc acatttaatc
    76261 ttggatttaa tgaactatat gggtcttgaa atatcatttg cattttgggt ctcaactttc
    76321 taagttcttc cttctctaac ttatatatat ctataccatt aaattcaact ttaccttcag
    76381 ttttttcaat taacctaaga atggttcttc ctgcacttga ttttccacat cctgattctc
    76441 caactatagc caaagtttct ccttttttta aatcaaaaga aattccatct actgccttta
    76501 cgaatttaat ttctttgcca aataatccag atttaacttc aaagtacttt ttaagacctt
    76561 ctacttttaa taaactctct tcttttttca attatatctc ctccttttta tataaccaac
    76621 atgcaatact atgaccacta ttcaattcta ttaaaggagg tatctgagtt ctacatttat
    76681 cacatacttt ttcacatcta tcactaaaat aacatgaatc tggtattcca attggatttg
    76741 gtacttgtcc tggaattgaa tataatcttt tatctttgtt ttttccaaga acaggctttg
    76801 attttagaag gccaatagta taaggatgct ttggattttt aaacaattca acaacctctg
    76861 ctacttctat aattttgcca gcatacatca ctactacttt atcacacatt tctgcaacta
    76921 ctcccaaatc atgtgtaatc atcattatag atgtatttaa tttttctttt atatttttca
    76981 ttatatctag aatctgagct tgaatagtaa catctaaagc tgttgttggt tcatcagcta
    77041 taagtaattt tggattacat gataaagcca tagctatcat tattcgttgt ctcataccac
    77101 ctgataattc atgtggatat gaattatata tttcttcagc tcttggtatt tctaccagtt
    77161 ttatcatatc tattaccttt ttcttagctt cttcctttga taaatcttga tgtaacataa
    77221 taccttcaat gatttgactt ccaacagtaa atgctggatt taaagatgtc attggttctt
    77281 gaaaaatcat tgatatctca ttccctctta ttctcataag ctcattttca ttcatcttta
    77341 aaatgtcttt gccttgaaag attatttctc caccttctat ttttgatgtt ggaagtaact
    77401 tcatcaaaga catggctgtt acagatttac cacatcctga ctctccaact attccaatag
    77461 tttcaccttc atttatatta aaacttactc catttacact ctttacaatt cctttatctg
    77521 tatgaaaata aacttttaaa tctttaactt caattagtgc tttactcatt attttctcct
    77581 ctcagcaaaa ttgcttaaaa taacatacac cttttgattg tattttataa aaatttaaat
    77641 tacaacattt tattacattt tattattttt ttctattaat tataatattg taatagttaa
    77701 tttctatata tattgattta ataatgatta ttattataca atgaaaaata tgtgttaaat
    77761 attattttat ggaggtttta taagaatatg aaatttaaaa aattggcatc attaatctta
    77821 gtttcagcat taatgcttac atttacagct tgtgcttcta atgataaaga aaagtctaat
    77881 ggaggcaaat ctggtggaac tgttgtaatc cctatggcaa gtgaccctga tataatcaat
    77941 ggagcttttg caaatgttaa agaagattct cttgcatcaa atatagttta tgctcctctt
    78001 tatacttatg aaaaagggaa tttagtaaat tatctagcag aaaaagtaga ttttaaagat
    78061 agtaaggaat taactataaa attaaaatcc aacttaaaat ggcatgatgg aaaaccaata
    78121 actgctgaag atgttttatt tacatttaat acagttttag acgaaaaaca aaattcacca
    78181 tcaagacaat acttattggt gggtgagaaa ccagttaaag tagaaaaaat tgatgattta
    78241 acagttaaaa ttactttgcc aactgcaagt gaatctttct tatatggtat atctaaaatt
    78301 tctcctatac caaaacatgt gtttgaagga gaatcaaata tagctaagtc agaaaaaaat
    78361 aataatccag ttggttctgg tgcattcaaa tttaaagaat ggaaaaaagg tgaaagcata
    78421 gtatttgaaa agaatgaaga ctattttggt ggagaaccta aggcagattc tatagcacta
    78481 aaaataatac ctaatgaagc atctcaagaa gcagctttaa ataatggtga aatttcactt
    78541 atgaagacat ctgcagaagg atatgaaaag gcaaaatcaa actcaaactt acaaacttat
    78601 acttatagtg aagaaagatt aaactacatt gtatttaacc aaaatatatc aaacatggct
    78661 aataaagaag ttagacaagc cttatcatat gcattaaata gaaatgaaat gatagaatca
    78721 gcgtatggaa aagaaggctc tgtacctgct aaatctatat tagttccaga agcagacttc
    78781 tatacagaag aaggtgttga aggatatgac caaaatacaa ataaagctaa agacttattg
    78841 gataagagtg gtgttaaaat tgataaatta aaaatagggt ataacacagg tagatttggg
    78901 cataaaaact atgctttagt agctcaacaa gagttgaaaa aaattggtat agaagctgaa
    78961 atagttcctt atgaaagtaa ggcattcttc aatatactat ttagtaatag cactgaatgt
    79021 gatatgtatg taaatggtta tgcttgggga ttagaaccaa atccatatag aggtatgttt
    79081 gaaactggtc aatattgtaa ccaaactaaa tattctaatg ctaaaataga tgctttatgg
    79141 gaaaaaggat ttactgagtt aaacaaggaa aaacgtgaag aaatatataa gcaaatacaa
    79201 caggatatat ctaaggatgc acctatttac actatagatt atgaacaaaa tttaatggca
    79261 gctcaaaaaa atctaaaagg aatagaagat gctaaaccat ctcctgcaat attatttgaa
    79321 gattggtcta aattgtatgt agaataattg atgtaaaatt ttatattatt aattagaaaa
    79381 ggagatgtct aaaaataata ttgttttatt attttaaaat gagacatctc ttttaattag
    79441 gagaatttac ttatgttaaa attaatattg aatagagtga aagttttaat acctatgtta
    79501 atcttaatat ctatattatc atttggactt ttagaattag ctcctggtga cccagcagat
    79561 gcatatataa atcctttaat gtctgcacag gatattgaaa atataagagt taatatggga
    79621 ctcgataaac cagtatacgt aagatattta agctggttga aaaacacttt aagcggaaat
    79681 ttaggtattt cttatataaa ccatatgccc gtaacagaac aaattatgga aaaaatggga
    79741 aatacattta ttcttatggg tacttcttta atattttcaa tattggtagc tatacctctt
    79801 ggaatatttt tagctgtaaa taaaaattca ataactagta aaatatcatc tatttttaat
    79861 tatataggtg tttctatccc ttctttttgg ataggtatga tactcatttc aattttttca
    79921 gttaaactta acatttttcc atcaggaggt atgcatacta ttggaaatga tagtattgga
    79981 gatttagtaa aacatctagt tttgcctgta ataactttag gtctatataa tactgctatt
    80041 tttacaaatt atgtggaagc tagtgtaaat gaacaattaa aaaaacagta tgttgttaca
    80101 gcaagagcaa aaggattatc agaaaaagtc atactattta aacatgtctt gaaaaattca
    80161 ctgacatcat tggttacaat cctaggcatg agtatacaaa aattagttac tggcgcattt
    80221 gttacagaag tagttttctc ttggccaggt atgggaagat taatgattga ttcaattttt
    80281 tcaagagatt atactgtaat tatggcaata actatgttat cagcactatt tttaatttta
    80341 ggtaatttgg ttgctgatat actatactta ttgattgacc ctaaaataaa atctagcaag
    80401 ggaggattct agttatgttt acaaatatct taaaagaatt aaaaaaagac aaatcctttg
    80461 cttttgcatg tattactctt agtataataa tcatattaat tatagcttct tttatattaa
    80521 atatagactc taatgcaatt gatactactt ctaaacttca agaacctagc ttaaagcata
    80581 tctttggtac agatgaactt gggagagatt acttctctag agctctttat ggtggaagaa
    80641 tttcacttag tgttggtatt ttatcaatgc ttatttctgt agtatttggt actgctgtag
    80701 gtgttattag tggatatatt gggggtaagc tagaccaatt cttgatgaga ctagtagata
    80761 tgcttatgag tataccaagc ttcttagttt tgattgtatt aaatacttat ctaacaccta
    80821 aaatttccac tattatacta attattggat tcttaagctg gatggaagtt tcaagaattg
    80881 tacgtggcga aacattaaaa ataaaggaaa atgaatactg tctagctgct aaagctaccg
    80941 gtatcaagac tagaaatata ctattaagac atatagtttt aaacttaaaa gagactattg
    81001 tagttgctgg ctcattaaat attgctaatg ctatcttaac tgaatctgct cttagttttt
    81061 taggtcttgg aatccaattg cctcttgcat catggggtaa tatgcttcaa gatgctcaaa
    81121 aatatatttt tgacaagtta tatttagctg tatttccagg actacttata tttttaacag
    81181 ttatgagttt tactataata agcaaaaaat tttctagtaa tacttaataa attttatata
    81241 gaaaataaaa acagtgatta tccaaagata tacactgttt ttatttttcg ttttaaaaag
    81301 cacatatttt gtataatata actttaaata ctactctagc atttatgtaa aacctgctat
    81361 tgctctcaag cacgtagatg aaaaactaat agtttattat aataaaaatg gttttattta
    81421 tttgttattt taataacact tttaagagtt ctttttacta aagaaatcta taataaattt
    81481 aaatacatgt tggtctacat ggctataacg ttctttttta ggtctacata gtacaacttt
    81541 ccatgtaata ggataattga aaggtttttc tataattttg ctattttcaa aaaaatcatg
    81601 aactggtgat ggtagaatgg ttataaaatc agaatttgta gtcgatagca acaaaaaatc
    81661 ccatgaacca gacattatat atctctttag tttaacattt tcatcagtaa atttttgcat
    81721 tagcttatga tgtatcataa aagtaggatt aaatattgca agtaactgct cattcaaatc
    81781 gttccaatct atcttatcct tcttagcaag tggatgattt atatttaaaa atgctgtaag
    81841 ttcatcttct tgaagcacat gttcagtcac tacactttta tcaattttat gtggatgtaa
    81901 tagcactgca taatctaatt cttgtaagat aagcattcta cttaaatcat atgctcccct
    81961 ctctactatg tcaaattcta tatctggatt atttgcaact aactgtgcaa ctacatctga
    82021 aaatactatt ccaagtataa gtggaggtat tcctattcta atttttcctt taaattgaac
    82081 tgaatcttct cttaaatctt ccatcatatt tttgtattca tttataatat gttctgcatt
    82141 tacataaaat ctttcccctg ctggtgttaa cccatttaac ctacctttat acctttcaaa
    82201 taaatataca tcttcacttt cttcaaaatt ttttataatt tgacttagtg ctggttgaga
    82261 tatatgaagt gtcttagatg ctattgataa attaaaacca gatttcacta tttcaacaaa
    82321 atattttaac tgttttatat ccattttaac cccccttccc caaaagtata atttagatta
    82381 tattttttct tataatgata ttttatagga aaatcaacat aatttcatta atattttaac
    82441 aaaatatttt tctaaatctg ctctaaattt ttgtcctata aatttttctt atacactata
    82501 taaaaaatta gacttagaca aaacgctttt ttcgacgtaa tctataatta gaaacaggaa
    82561 aacctaaggc attgggaata aaaataattg aaatacttaa aaacaagctt gtattagaag
    82621 tactttatta tagtgttcca tatttttctt attcagaaaa tttttaatta tcattcaaga
    82681 aaggtaacta ttagatatga aagacgtagt aatcgtatca gcagtcagaa cacccattgg
    82741 aaattttgga ggtgtattta aaaatacttc agctgttcaa cttggaacta tcactgttaa
    82801 ggaatcaatt tcacgtatag gacttaattt atctgaaata aatgaagtaa taattggaaa
    82861 tgtacttcaa gcaggacttg gacagaatgt tgctagacaa attgctataa atgcaggtat
    82921 cccaaattct gtcccaagtt atacaataaa taaattatgt ggttcagggc ttaaaagtgt
    82981 tcagctagct gctcaatcaa ttgcatctgg tgaaaatgat gtagtcattg caggtggcac
    83041 tgaaaatatg agccaagctc cttatattgt tccaactgcc cgttttggta ataaaatggg
    83101 cgacataacc atggtagaca gtatgctaac agatggtctt attgatgctt tcaatcaata
    83161 tcacatggga ataacagcag aaaatatcgc aactaaattt gaatttacta gggaaatgca
    83221 agataaatta gcattagaaa gtcaaaataa ggctgagaag gctataaaaa acaagcgttt
    83281 taaagaggaa atcattccag tgaatatctt aatacgtcgt ggaaaaatgg aaactattga
    83341 cacagatgaa tatcctaaat taggtatgac atttgaaggt ttgtctaaac ttaaacctgc
    83401 attcaaaaaa gatggtactg taacagctgg aaatgcatct ggtattaatg atggtgcagc
    83461 catgctaata ctaatgagca aacaaaaagc agacgaacta ggaattaaac cacttgttaa
    83521 aataaaatct tatgcttcag ctggtgttga acctgaaatc atgggtacag gtccaatccc
    83581 tgcaactaga aaagcactga aaaaagctgg gcttagtatc aatgatatag acttaataga
    83641 agcaaacgaa gcatttgctg cccaagcatt agctgttaaa aatgaacttc aaatagattc
    83701 atcaaagtta aatgttaatg gtggtgcaat agcattagga catccaatag gagcaagtgg
    83761 agctagaata cttgttacct taatttatga aatgcaaaaa cgtaaagtta aaactggact
    83821 tgcaaccctt tgtattggtg gtggtcaagg aatatcaatg gtggtttcac gataggagga
    83881 aatatgaata aaatagttag tattgatgaa gctctatctc atgtaaaaga tggagataca
    83941 ataatggttg gtggattcat ggccaatggt tcaccagaaa atttaattga ttatttatgt
    84001 agtaaaaata taaaagattt gacactaatt tgcaatgata ctggctttat tgacaaagga
    84061 gttggcaaaa tggttgtaaa taagcaattt aaaaagataa ttgcttctca tgtaggatta
    84121 aataaagaaa ctggaagaca aatgaacaac aatgaaacag atgttgagtt agttcctcag
    84181 ggaactcttg ctgaacaaat acgtgcagct ggttatggtc taggaggtat actcacaccg
    84241 actggtattg gtactcttgt tgaggaggga aagcaaaaaa ttgttgtcga tagcaaagaa
    84301 taccttcttg aaaaaccaat ttatgcagat gttgctcttc tatttgcatc aaaggtcgat
    84361 aaagcaggta atctagttta taaaggctct atgaacaatt ttaataattt aatggcatct
    84421 gctgccaaaa ctacaatagt tgaagcagat gaaatcgttg aaattggcga tattgaccca
    84481 aatgaagtta atacaccagg tatttttgta aattacatcg ttgaaggagg taatttataa
    84541 tggataaatt agaaatgcaa gaatatattg caaatagagt atctaaagaa ttaaaagatg
    84601 gagctgttgt aaaccttgga ataggtctgc caaccaaagt agcaaattat attccagatg
    84661 atgtaaacgt tatcttgcaa tctgaaaatg gatttttagg tttaggtgca gctgaagatg
    84721 gaaattcaaa tgatgaaact attgtaaatg caggtggtca accagttact atactgcctg
    84781 gaggatgttt ctttgatagt gctacttctt ttggaataat cagaggaggt catgttgata
    84841 taactgttct tggtgcactt caggttgaca aatatggcaa catagcaaat tatatgattc
    84901 caggtaagat ggttccaggc atgggtggag ctatggactt ggtgactgga gctaaaaaag
    84961 ttattgtagc aatggaacat acttcaaaag gttctgcaaa aatattaaat aattgcactc
    85021 ttccacttac tgcaacaaat gctgtagatt tgatagtcac tgaaatgggg gttatggaag
    85081 taacatcaga tggaatttta cttaaagaaa taaatccagc tttcacattg gatgatgtta
    85141 tttcttctac tgaagcacct ttgatattgt cggattcatt aaatggaaac atatctgttg
    85201 tttaaaataa ttaaaactag aaaataaaaa tgtcttagat gtattagata taaatttata
    85261 ttacttaaaa tattaatata aaaataaaat aaaattggag gaaatgaaaa tgcttaaaga
    85321 taaagttgta ttcgtaacag gagctgcaag tggaataggt aaacaaatag ctgaatcatt
    85381 cttaaaaaat ggtgctaaag taatgttctc tgatataaat caagaagctt taaataagac
    85441 cacaacagag ttacaacaag aaggttatga ttgcatgaat gtaaagtgtg atgtaactaa
    85501 ggaagaagaa attaaccaag ctatagacaa aactgttgaa aaatatggca gattagacat
    85561 attaataaac aatgctggac ttcaacacgt ttctatgata gaagatttcc caacagataa
    85621 atttgaattt atgataaaaa taatgctaac agcacctttt atagctacca aaaaagcatt
    85681 tcctataatg aaaaaacaag gctttggtcg tataataaat atggcatcaa tcaatggtgt
    85741 aataggattt gctggaaagg ctgcttataa ctcagcaaaa catggactta ttggactaac
    85801 aaaagttgct gctcttgaag ctgctgattc tggtataaca gttaatgctt tgtgccctgg
    85861 atatgtagat actccacttg tcagaggtca gtttaatgac ctttcaaaaa ctcgtaatat
    85921 accattagaa aatgtcttag aggaggtttt atacccactt gtgccacaaa aacgcctatt
    85981 agatgttcaa gaaattgccg actatgctat gttcctagca agtgataatg ctaagggtat
    86041 tacaggacaa gcttgcttac tagatggagg atatactgca caatagttat tatatttagg
    86101 gcttgaagaa cttattcttc aggtccttct actaaggagg aatatttatg agtattatcg
    86161 caccaattgg tataattatt ggtatcatag ctattatata tttttcagtt aaagaaattc
    86221 atataactat agctgctcca atagcaactt taatagttgt tctcttaaat aaaatggatg
    86281 ttgtaacatc aatgctaggt gctgacaaaa acaattatat gggggcactt ggaaactata
    86341 taatgagtta ttttgcaata ttcttattag gttcaatact tgctaaattt atggaagaaa
    86401 gtggagctac tgtatcaata gctgatttta ttttaaataa atttggttct aatcatcctt
    86461 atagagtttt agttgctata tttatagtaa gttttatatt aacatatggt ggtataagct
    86521 tatttgtagt tatgtttgca gttattccac ttgcaagaac tctatttaaa aagcttgata
    86581 tttcttggaa ccttattcag ataccacttt ggcttggtat tgcaacaatt actatgacta
    86641 taattcctgg aacaccagcc attcaaaatg ttatacctat tcaatatcta aatacatctc
    86701 ttactgcagc tactatacca agtgttgcag gtagtatagg ttgtgctacg tttgggcttg
    86761 tctacatgaa atatgctcta aacaaaagca ttagaaaagg tgaaacttat gcaacttaca
    86821 cttcagaatt agaagaagaa tctttagcta gggaattacc aggatttttt gcaagtattt
    86881 ttcctctatt agcactcgta attatagcta taactggaag tacttttggt tcagaattta
    86941 tgaaaaaaaa tgtaatttac atagctttaa tagttgcaat tcttttatct gcttttttat
    87001 tccataaatt tttatcatct aagatacaga cattgagtat aggtgctagt ggttctatag
    87061 gtcctatatt tgctacatct tctgcagttg catttggagc agtaataatg gctgcacctg
    87121 gttttgatgt atttagcaag cttataatgt caataccagg tagtccactt ataagtctta
    87181 ctgttttgac ttcaacaatg tcagcaataa cagggtcatc ttctggtgca ttaggaatag
    87241 taatgccaaa ctttgcagat tattatttaa gtactggtct aaatccagaa ttaattcacc
    87301 gtgttgctac aatagcctca aatatactaa ctatagttcc acaaagtggt gtttttctta
    87361 cattcctaag cctctctaag ttaacacata aaactggatt taaagaaact ttcattgtag
    87421 ttgcagttgg ttcactaata gcagaaatca ttgtaattac attaggatta ttaatgtatt
    87481 aatataaaat aaatcagaaa ttacaatata aaagggaatg tctcaaaatg aattttttag
    87541 ttaatgagac attctttttt gtatgaaatc acatatacat ttattatttc aacaatggaa
    87601 gtgaggcttt ctctattttg atgtagaccc ttttattcct taaagattta aataattata
    87661 atttgttact aatattaaag catttattta ataaatttaa ctaaataaaa aaaaaattta
    87721 tcataactat aaatttgcat tatagaatta ttataaaaat attatttgct ctaaataagt
    87781 aattccatac tatacacact tctaatacaa actgtcaaac actctgaaat atgcctaatt
    87841 attccatata tgtctttttt acatatcttt acagtaaaaa aatacttgaa attgtgttag
    87901 tatagattca cgggtacccc ctacactaaa ggttacaaat tagtaacatt tttagaattt
    87961 ttagattgag aggtgtttag taatgagaaa aaatatacca acaaaattaa aaactatatt
    88021 agctttagga gtgttaacct taacaacagc ttccagtgct gttaatgcaa gtgctttatc
    88081 acttgaaaat aatgtaaata caagtaacaa aaatttagta tacagtaata ctaggtacaa
    88141 attttctgca aaaccaaatt gttctataaa accagaactt aagcctgata aagacaactc
    88201 ttgcaaagat aagaatcata gtgacaaaaa ttgcaacaat actaataaac ctgataacaa
    88261 taaaccagag tctaataaac ctgatgacaa taataattca ggttctactg ataaacctga
    88321 caacaataaa ccagagtcta ataagcctga tgataataat aattcaggtt ctactgataa
    88381 acctgacaac aataaaccag agtctaataa gcctgatgac aataataatt cagactctac
    88441 tgataaacct gataacaata aaccagagtc taataaacct aatgacaata ataattcaga
    88501 ctctactgat aagcctaatg ataataacaa ttcaggctct acaagtgaaa atttttcagc
    88561 ttaccaaaaa gaagttgtcg acttagtgaa tatagaaaga tctaaagctg gattaaatcc
    88621 tcttactctt gattcttcta tatcaaacgt tgctacaaaa aaatctcaag atatgattga
    88681 taacaactat ttttcacaca attctccaac ttatggttct ccatttgata tgttgaaaaa
    88741 atttggaata agctataaaa cagcaggtga aaatatagct atgggtcaaa agacaccaaa
    88801 agaagttgta aatgcgtgga tgaattctga aggtcacaga aaaaatataa tgaatccaaa
    88861 tttcagtaaa ataggtgttg gagtagcaca aaaaagtggt ggttcaattt attggacaca
    88921 aatctttgta ggataaaata ctctttttcc atacatatca aaagggtatc tctaagtgat
    88981 aaaaaacaca caaatgagat actcttttgt atctatattt aaaattatta aatacaaaca
    89041 tatatagtat aaatagtatt gttctctacc agtgattttg atgtacagaa caatatataa
    89101 aaagtattgg caatatgaaa atggaaaact taaaaaaggt atttagcaga taaaaacaaa
    89161 atcttaatat caaaaatgaa aaagagtctt gtcttaaaat agagacaaga ccctttttca
    89221 ttgttgatat gattaaaata tattttattt tatataaaaa agagtgcctc atgaactaaa
    89281 aagttcactt tgagacactc tttttatcaa ttctatataa gcattataat actttaatat
    89341 tattcagcta attttttgta tccttcatat ctttctttag catcagcttc agctttagca
    89401 aataatccat cagcttcctc tgggaattgt ttagctatag cagaatatct tacttgtgca
    89461 agtatgaaat ctttgaagct tgcagttggt tcttttgaat ctaaagtgaa tgggttttta
    89521 ccttcagctt ttacttctgg attgaatcta tataaatgcc aatatccgca agcaacagct
    89581 tgtgcttcgt tagctacagt tcttcccata ccttctttta atccatggtt tatacatgga
    89641 gcataagcta ttattagaga tggtccatca tgtttttcag cttctagaac agctttgata
    89701 aattggtttt tatcagcacc catagcaact tgagctacat atacgtttcc gtatgtcata
    89761 gccatcattc ctaaatcttt ctttctagat tttttacctg aagcagcaaa cttagccata
    89821 gcagcagctg gagtagcttt agaagcttga cctcctgtat ttgaatatac ttctgtatca
    89881 aatacaagca catttacatc ttcaccagat gcaagaacat ggtctaatcc accataaccg
    89941 atgtcatatg cccaaccgtc tccacctagt atccattgag atctcttaac tagataatct
    90001 tttctatctt ttatagcttt tactaattct ttagcttttt catctgtaca atcacaagct
    90061 ggtttttcta ataattcaac aaccttagca cttgctactt tagaagcttc tccatcattt
    90121 ctagaatcta accactctgt aaatactgct ttagcatctt cacagatatc catagaaact
    90181 agctctgtca tagcatctac tattttgttt cttatttgct taacagctgt gtacatacca
    90241 aatccatatt cagcattatc ctcgaataaa gagtttgccc aagatggacc tttaccttca
    90301 tggttacaag tataaggaat tgatggtgca gaagctcccc atatagaaga acatccagta
    90361 gcattagcta tcatcattct atctccatat aattgtgtaa ctactttaat gtatgcagtt
    90421 tctccacatc cagcacatgc tcctgagaac tccattaatg gttgtctaaa ttgacttcct
    90481 ttaacagtat ttgcaggcat aacgtcaact tttggagcta cttcatcagg atttactgca
    90541 aatgcccaat tatctaactc tgtatcaagt tgagtatcta ttggcttcat aactaaagct
    90601 ttttctttag ctggacatat atcagcacag tttccacatc ctgtacagtc aagtggacta
    90661 acttgaattc tatattttaa tccttctaat cctttaccta atgctttttt agcttcaaat
    90721 ccttctggag cattagctag ttcttcttca gtaactaata ctggtcttat acatgcatga
    90781 ggacatataa aagaacattg gttacattga atacagttat ctattatcca ttcaggaaca
    90841 tcaacagcta taccacgttt ttcataagct gcagtaccac aagggaatgt tccatcttct
    90901 ataccattga atgtacttac tggtaagttg tttccttctt gtgcagtcat tggtcttagt
    90961 atatttttta taaattctgg ttctttaact tctcctttat ctgcatcaac agcattttcc
    91021 caagaagctg gaacttcaac tttaactaaa gcatttattc ctgcatcaac agcagcatag
    91081 ttcatgttaa ctattttttc acctttttta ccataagctt taactataga atcttttaag
    91141 tatttaacag catcttcttc tggtattatt tcagctaatt taaagaatgc agattgcatt
    91201 atcatgttta ttctgtttcc aagacctatt tcttgtccta gtttaacagc gttaactgta
    91261 tagaatttta tatcattttt agctatatat tgcttcatat gagctggtaa atgttcttca
    91321 agtcctgctt ggtcccatat agtgttaagt acaaatgtac cacctttttt aagacctttt
    91381 aataaatcat attgataaac atatgattgt ttatgacagg caatatagtc agcttcatct
    91441 attaaataag tcgctcttat tggactatca ccaaatctta agtgagacat agttactcca
    91501 ccagattttt tagagtcata atcaaagtaa gcttgagcgt atttttcagt atggtcaccg
    91561 attattttta tagcttgctt attagctcca acagtaccat cagaacctaa tccccagaac
    91621 ttacatctta tagttccttt agaagctatt tttattggtt cagatggagt taaagaagta
    91681 ttagttacat catcaactat acttactgta aatccatttt taggttgttc tgaaactaag
    91741 ttatcaaaaa cagtttttat atctgaagga gtagtgtctt ttgaacctaa tccgtatctt
    91801 ccacctatta tcataggagc attttctttt ccatagaata catcacgtac atctaagtat
    91861 aatggttcac cagttgaacc tggctcttta gttctatcaa gtacacatat tctttcaaca
    91921 gtagatggca tagcatctaa gaaatgtttc attgagaatg gtctatataa atgaacttta
    91981 actaaaccat atttttctcc cttagcattt aagtaatcta tagtttcttc tattgtttct
    92041 gttacagaac ccatagccac taatacgtat ttagcatctt ctgctccgta gtaatcaaat
    92101 aaactatgtt ttctacctgt taaattactc attttttcca tgtatttttc aactatacct
    92161 actatatttt gatagtattt attagaagct tctctagttt ggaagtatat atctgggttt
    92221 tgagcagtac cacgagcaac tggatgattt ggagataaag cattatctct aaatgcttga
    92281 actgcttcaa agtttaataa acttgcataa tcttcatttt ctaataattc aactttttgg
    92341 atttcatgtg aagttctgaa tccatcaaag aaatgtataa atggtaatct accttctatt
    92401 gcagctaaat gtgcaacagg tgctatatca gctacttctt gaactgaacc agaagctaat
    92461 aatacacatc cagtttgtct agcagccata acgtcttggt gatccccaaa tattgataaa
    92521 gcttgagatg ctaaagcacg agcacttaca tggaatactc ctggtaataa ctctcctgca
    92581 actttataca tgttaggtat cattaataat aaaccttgag atgctgtaaa agtagaagtt
    92641 aaagctcctc cttgtaaaga accatggaat gttcctgatg cacctgcttc tgactgcatt
    92701 tcaacaacat taactgtttg tccaaatata ttttttcttc cttgtgatgc ccactcatca
    92761 actacttcag ccatagttga agatggtgtg attggatata tagctgctac atctgtaaac
    92821 gcataggcaa catgagctgc agctgtattt ccatcaagtg ttttcataaa cttagccata
    92881 atatgtatcc tccttgatag ctacaattgt acttgtttat aacaagtcta tttttttata
    92941 tttacatata atttacacaa caaaaatata aacacacata tagtcgcgca aatactctat
    93001 cttctaatat aatactacag attagataaa attcctttga aaattgtaaa ttaattacat
    93061 atttaagtag attttttttt aaattaaata tgttaagttt ttttcataat tttgtataca
    93121 atatataata aattaagtta gacttttcaa acttttttat ctatttgttt atattagtat
    93181 aaaaagtaaa atgattatcc ttattatatg taaattttta tatatataat tttaccatat
    93241 tacatcatat ttttgtaagt ttttattaca ttttttataa taccccttta ttttataaat
    93301 taatctaatc gattaaattt atcctataga aatttattac atttaaaaat atgctagcaa
    93361 ataaaatatc tactagcata aagtctattt ataatattaa tcaactatta attctactaa
    93421 gtctccattt ttaacgcctg ctgcatttcc ctcttccata tcaacatgca tttctagatt
    93481 aaagctatca ctagctctta ctaatacatt ttcaaatact aatgctcttg gtccagatgt
    93541 tttaactttt actatttgtt tatcagttac accaaattta gcagcatctt cattgctcat
    93601 atgtatatgt ctagaagcaa ctataactcc ttctttcatt tcaacttctc cagcaggacc
    93661 tactagttta acacctggag ttccagctat atcaccagat tcttttattg gtgctttcac
    93721 tcctaatggg aaaccatctg ctaaagatat ttcaacttga gtatgagctc tagctggtcc
    93781 tagtactcta actcctttta aagttccttt tggtcctact aaatccactt tttcttcaca
    93841 ggcatattgc cctggctgag ataatggttt aaatttagtt aactcatgac ctgcaccaaa
    93901 taatacgtct atatcagctt gactcaaatg aacatgttta ttggataatg ctattggtaa
    93961 tttcattgaa atttcctcct tttaattatt taaattattg caatacaatt atacataata
    94021 ttacctacaa aatcaaatta tattgaatca atatatctct ttaaattttt atatattata
    94081 tctttaaatt cttgattgct catataagat acattgtctg tatcgtttaa atatatattg
    94141 tgtaaaagtt tagtatttat actcttaaag aaaaaatcca taacaatctg tccaccttta
    94201 aactgtgaat catatgattt actaccccct actgcaatat acattcctat ccgtttcttg
    94261 tttctatcaa ttgagggctt atttaatata tatttacttg catatatagc ttgtgttcta
    94321 tcaacaactg tctttaattt agctgatatt gaatcaaaat gtacaggact tattactata
    94381 gttccttttg aatcatcaaa cattttatat aatggcttca tatcatcatt aaacttacaa
    94441 taccctgttt tttcacaaaa tccacatgct gtacaatatt caatatccat atcgtatata
    94501 ttaaatattt tacagcttag tccatactct tctagcatag cttttacttc atttgctata
    94561 aaactgcaat ttttattaat tcttgggctt ccatttatta tcataatctc tggactttta
    94621 agtccttttt tatcagttga atccataatc aatctaccta tcctttaaca taactattaa
    94681 aatatcatca tcataattat cttttgatga gaaattcttt aaatccaact ttagattctc
    94741 tactattaac tgttgattta atctaaagtt ttcttttaga aagttttcta atctgtttat
    94801 accatactct tcttttgatg aattttttat ctctaaaatt ccatcagtat acatacatac
    94861 cattgcataa tcttccattg aaatagtatt attttcataa ctagcatctt ccattattcc
    94921 aataggtata ccctttttac aatttaaatt attttctatt gtaccatcct tctttacgac
    94981 tacaggacta tagtgacctg cattagacac tgtaatcatg ttttctttag tatctataat
    95041 acctatcaaa caagttgtaa atactcccat cttgtcaaat tcatcatata acatcctatt
    95101 tagatttgtc attatttctc ttggtgtatt gtattgatta cataatacct taaaagcacc
    95161 ttttatcatt gcaacaacat aatttgatac cattccatgt cccattacat cagcaacaat
    95221 ataaactata tgttcgtcat ctacttttat agcataataa aaatctccac ctactactct
    95281 tgctggttta tgataaaaat aaagttcttt ctcatcatta caatccattt tacctttatc
    95341 cataataagc tgttgctgtt tatttaatat gttcagctca ttttcaagaa ctttgtgttt
    95401 tacttccttt tcattatgtt catataattg cataccaaca gaaacttgtt tggacagtat
    95461 actaagaata ttcaaatcat cactagtata gtttttacta tttgcacaaa ctatacatcc
    95521 tatagtctca tttttatcct ggagtttgta atatatataa ctttccaaat ttattccttt
    95581 ttttgagcat ggttttaaat tatttagata ccctcccaat gattctttct ttaaaaacgt
    95641 atcaatcata ggatataaat ttgttttctt tttttgctca acattataac agctaactat
    95701 agcatcctta ttatgatgac tatttataat tattaaagct tctttactat tagtaatatt
    95761 gcatgcttgt ttacttaaat tttctaaaaa gccatcaata ctcttattaa ggtatagttt
    95821 tttagtagct tcatttatgg cacttattga gcctcttagt ttatcaatta aaatttgtac
    95881 attattattt ttattagtta tttctattga taaacttaag agtgatgcaa cagatgatat
    95941 aaagtctata tcttgttctg ttaaataatc atcctctttt aaaaaacaag tcataaatcc
    96001 aacaactaca ttatttatta taaaaggaaa aactattctc ccaatataac cttcagcttt
    96061 tgctaaatct cgttcacctt ctgctctgga atcttcaaat acattttcca catatattat
    96121 ctttttttca tttacagcct catgtatata ctctggatac gtgtcaaaat caatttttgc
    96181 acctttaaga ctatttattg gaaaaatttg aggtacatat tctaaggttt gtgaacatac
    96241 taagtaggca tatttagaat catttttata aaatagattc acacatgcct ttgtagggtg
    96301 aacaacttct aacatttttt ctattatgtc atcttttata ttaaaaaaat ctgtagattc
    96361 agttaccata gcggatatct ccactaaatt cttcatttta taactgccat tagtcatact
    96421 caatttctcc ccctatatat taaactattt attagtattt taacatacat tctttatagt
    96481 aaaaacaaaa acaacgacaa aactagcaac taatatccag ttaaatcctg ttaataatcc
    96541 tataagaagt aatgtaatta atgcatttag acctgttcta cctttttcat ccataaaagt
    96601 tattttagag atgtcgatat tatttttcac attatttata tgttctttta cttgttcttc
    96661 catatttctt ttatatagta tataaactac accaactaaa aatactccta tacctagaac
    96721 catgtttaaa ttaaaagcta ccataagcaa tattgaacca aaagccaact ttaaaagctt
    96781 aaaaaatata ctatctatct ttaaggttat atttctgatt tctttacatt cgtctcttaa
    96841 agaatatcca cttgaatcta agttattaat ctttgttttt acaatttcag aataaaaaag
    96901 ttttattatt ccatttaaca ttttcatcac tcctaaatat tttacatata tttgtaagtt
    96961 ttacaattat aatatttttt atacttggta ataataaaaa ataacaaata ttttatgatt
    97021 tagtatttat tgtaaataaa ttattgaagc tttattagtt aagtatagat ttttaataac
    97081 tatttttata attagaagga agtggttttg tgcaaataga acaacttgat ttagaaacga
    97141 gaaataaaat atactgctat acaaaaaaaa ttcttagaaa gtatcaaaaa ggtataacat
    97201 ctggaaaatt aacagccgat aaatttgcag ataatatatt gtctcaagat tttatcagta
    97261 gtatacttga tgaaaaaata gtcaatgaga ccaactttaa gatatcttat agaaactata
    97321 tagaaacttt gataaatatt caaaatgaaa atttatctaa ctttaaaaaa aaatctacta
    97381 aaactgcaaa gtgcttcaat atctctcaaa taacccaatt aaaaaactta ctaaacaata
    97441 ctggttataa tttattaatt ccatataaat acttaacttc tcgtgatata gaaggaatcg
    97501 ttactcttat taatactggg tctattgaac ttggaaatga gagaatctat aattatatat
    97561 ccaaagcata ataatttaaa cctattataa aaaggcaatt tatttaataa aaaatatttt
    97621 taatattaaa taaattgcct ttttaatttt ggactaaata ctgctatcca agtgcttttt
    97681 ctagtttaga taaatgttgt attggataat attttagtag ctctttaaac tgttctactg
    97741 atagaccttc tgttgttgta tatattctta ttttttcatc taagtcacta ttaataaatt
    97801 tgttttttaa atcctcaaaa tttacactac tcattttaca tcactcctta tgtaacatat
    97861 tcatttgtat tattttatcc aaatacataa aatttattac ataaaaatat atctatttaa
    97921 taatttaata aaaaaaagct atctcaattt agaaattact ttctatattt gagatagctt
    97981 tagctaaact aatagccaat agttataaat aattatttat aactatctgt tgctttttcc
    98041 agccatttgt tgttcagcca tttcaactaa ttttttagtc atgtatccac ctacataacc
    98101 attttctctt gcagtaaggt ttcctttatc aacttgttga taattactca taccaagttc
    98161 attagctatt tctaatttca tttggtttaa agcctctttt gctcctggta ctactgttct
    98221 gttgttgtta ttgttacttg ccatgttgat taccttcctt ctgtttaatt tattttgtgt
    98281 tgctgataat attatgtgat tttaaacatt tttaattcag gtaattttta gcaattaaaa
    98341 cctgctaaat atccagtaga aaaagctatt tgcaaattga atccacctgt atatgcatct
    98401 atatctatta cttctccagc aaaaaataaa ccttctacta attttgattc cattgtactt
    98461 gaatttattt catttacttt tacaccacca gaagttatta tagcttcatc aataggtctg
    98521 tatctcttta ctgtaaactt taaatttttt aataaatgga ctaagttttt tctctgctct
    98581 ctagaaattt ggtgaacaac tgtatctgga ttaatttcac tcaaatttac tattacaggt
    98641 attagttttt taggaagtaa atcatctaat gctttttcaa attttttatt tgtatacttc
    98701 tgaaaatctt tttgaattct tttatccagt ttttcctcat ctaatgcagg ttttaaatct
    98761 aatattatag tgtaattttc tttccttgta tctttcattc tacaacttgc agacttgatt
    98821 ataggtccat ctaaaccaaa tttagtaaat tcaagttctc caaaatcact ataaactttc
    98881 ttttgtttgc tattaaatac tcttatttca acatttctca atgataattt ttctaaatct
    98941 cttgtaaaac tttcttgtac ttctatacca attaaagatg gttttgtatc cataattgta
    99001 tgtccttgtg aaattgcaaa tttatatcca tcaccagtag aaccagtaag tggataactt
    99061 aatccaccag ttgctactac aactgaatca catttaattt ctttcttatt gtttaaaatt
    99121 actttttcaa ttttattatt cttagatatt attttttcta ctttcgaatt taataatata
    99181 tttactttct tacttttaag ttgtctttca agagcgttta caatatcaaa tgctttatcg
    99241 ctctctggaa aaaccctttt tcctctttct gttttagttt ttactccaag attattaaac
    99301 atacttatta catcttcatt tgtaaaagta taaaaagcac tataaagaaa ttttccattt
    99361 gtaggtacat tttctattag ttcttctatt tcacaggcgt tggtaatatt acatctacct
    99421 tttcctgtta ttgcaagttt ttttcctaat ttatgatttt tctcaactaa cgttacatca
    99481 cagcctctct cacatgcagt tgatgcggct atcattcctg ctgggccacc acctattatt
    99541 actaccttct tcaaataatc actcttttct acccttaatt tttttaattt aaactattga
    99601 ttatatacct caaatcaatt taattttaaa actttaaata atgctggagc tcctgctact
    99661 ccataaaaaa caactactgt attcttaata aaattcataa aatttatact catagtagag
    99721 tcacttatat ttaaagtaac tattaacatt gaaataaaca acttaatgcc aatatataac
    99781 attcctattg ttactatccc aaccaaaaac ctacatattc ttgaaaaaat tatattttta
    99841 ctccccttat ttttactgct aaaatttatt tttttgttat tattatctgt attaaattta
    99901 acaaatctat cctcaactat atatccaaat acaaacccta ctataatacc aaatttttca
    99961 aaatattcag agctatttag aaatatagct actattataa acggtataag taaaactaaa
   100021 agtaaaatat aatttttgtt atcatcaata tagtcaaata tttttataaa tattactgta
   100081 aaaaatatac ctaatatcca accagctatc acatctattg gccagtgaac agctaaatac
   100141 aacctagaca accctactcc taaaaccatc actgcaccta ttacatggat atatctcttt
   100201 ttaaatatag tcataatact aacccaaaac gtggttgcag tttgagtatg agcacttgga
   100261 aaagaataac cgccagcagt agaaactctc aatgactcaa gaccttttat tcctattggt
   100321 ctaggagctt ttacaaactc ttttatgcct aaatttacaa caaaatttcc aattatagca
   100381 aacagtattt tctgtccaca ttttttattt atacaccagt atataattgt tgtaattaat
   100441 attaataacg gtgcttctgt gcttatcgta agtacaagaa atataaagtt caaaattgga
   100501 tttcttaaat tttggaaaaa taataatata cttaattgaa tatccatata gatgtctcct
   100561 ttactaaaat tttatataat taactaaaaa gcactaactc ccttagaaat tagtgctttt
   100621 gattcacatt taaatctatt ctacgtcctc aactatacct atgtaaggta aatttctata
   100681 cttttcagca taatctattc cataaccaac aataaatttg tcttctataa caaatccaac
   100741 ataatctaca ggtatattag cttttcttct ttgaggtttg tcaagtagag tacacagttt
   100801 taaagatttt ggatttctag tttttaaagc tgccactaga ttacttaatg ttaaaccaga
   100861 atctattata tcctctacaa tcaacacatt ctttccttca atatctacat ctaaatcttt
   100921 taatatttta actgttccag aagactctgt tgaattgcca taacttgtaa cactcataaa
   100981 atctatattt acatccaaat ctatacatct tattaaatct gatacaaata cactagctcc
   101041 tttaagtata cctaccacta gtaaatcttc gcctttgaag tcttcttcta tcttctttcc
   101101 tagttcataa actttctctt ttatttgttc ttctgtcaac atttttcctg taactttgta
   101161 cattttgtat cctcccgctt tccttctatt aacttatata ttatagcata ccaaaatatc
   101221 aattaaaatc tttttcagca tttttaaacc taaattaaca gtttatccat acttttttgc
   101281 ttttttcatt aaaaatttgg aataacgatt cctttgtatt ataatctata tgtacatata
   101341 ttaatcagtt atttttctcg attatataat tttatttttg gaggtacttt tatgagcaca
   101401 aatcatggag ctaatttata tagtttatct agtaagtatg gcttttcaaa agaagaattt
   101461 atggacttta gctcaaatat aaatcctttt ggtacatcaa gtttagccaa acaatacatt
   101521 gtaaacaata tagatatggt atctatgtat cctgaccctg attacataga cttaaaaact
   101581 tctatatcca attattgcaa atgttctatg gataatatag tacttggcag tggagctaca
   101641 gaactaattt catcatttat acatacaatt aatcctaaac aagctctctt actctcccca
   101701 gcttattcag agtatgaaaa agagttatct aaaattaatt gttctatgga caaatacttc
   101761 gccaaagaag aagataattt tcatataaat ttagaaaatc ttataaaaac tatcaatgct
   101821 aaagattatg atttggtagt gatttgtaat cctagtaatc caactggatt tgcatttact
   101881 aaagtagaag tgagagaaat tttaaaaaat acagactcat ttttaatgat tgatgagact
   101941 tatgtagagt ttactgatac aaatacatac tcttgcactc aattagttga tgattattct
   102001 aatttattcg ttataagagg tacatcaaaa tttttttcaa cgcctggcat aaggcttgga
   102061 tatggtctta tatctaacac taatgttaaa aatgaaataa ataaaaatat agatttatgg
   102121 aatataaaca taatagcttc taaaatggga gaaatcatgt ttagtgattt agattttata
   102181 tcaaatacta tttctttagt aagtgctgaa agaaactatt tacttaaaga gcttaaaaat
   102241 ataaaaaatt taaatgtgta tgatactaaa ggtaatttca tattgtgtaa aataaagaca
   102301 aaggaattga ctgctaaatc tcttcgtgag aaactaattc ctcaaaaaat aataataaga
   102361 gattgttgtt catttgaagg tctaaatgaa tatttcttta gggtatgtat attaaaacct
   102421 aatgaaaata aattattaat atcatctctt aaagcaattt ttaaataaaa aattacttta
   102481 tcttataatt tgtacaatca tacttttatc atttcaacaa tgtaaaagag gcttatctct
   102541 attttgagat agcctcattt ttatctattt acaaactaag cactttgctt ttctttgctt
   102601 ccttttttac tcattccatc atttatttta tctactacta ctgctattgc attatctcct
   102661 gatacattac atgctgtacc aaaactatct tgtgttaagt ataaagctat cattaaactt
   102721 gcaagtccac catctgatgg tattccaacc attggtagaa aaggaagagc actcattata
   102781 gctccacctg gcgctcctgg tgctgcaacc attgctatac ctaacattgc aatataaggg
   102841 aataatacac ctattccatg tggcataccg ttcatcatta aaactgctgt tgtaaatcct
   102901 gttattgata tcatactacc tgataaatgt attgttgcac aaagaggtac aacaaattct
   102961 cttatttgct tacttactcc atttttttct gcacaaccaa cattaactgg tatagttgct
   103021 gctgaagatt gagtccctat agctgttaaa tatccaggta cttgattttt taacattctt
   103081 actggatttt ttcctgaaaa tacgcctgct gctgtgaatt gacatgccat atatacaaaa
   103141 tgtaaaggga ttactactaa atagactttc caaaatactc ctaatattgt ccatacttct
   103201 cctgctatag ttatatttgc aaaagttcct gctatgtata aaggtaataa aggtataatt
   103261 actgttgaca acgttttcgt tacaattcct tgaaattctt ggaagaaatt aaataaagtc
   103321 tctccttttc cgtgatttct taaagctgat attccaagtc ccattacaaa tgcaaatacg
   103381 attgcagctg ttacatctac cataggctct aatggaattg taaatattgg agctaacatt
   103441 cctgcctctg ggtctccaat ttgacttgca acactcgcat caataaaatt tgggaagatt
   103501 aatgtagata ctacaaatga taataatcct gctattaaag tagaaccata tgctattccc
   103561 gtagttatcc ccaataactt tccggctcct gttgctaaat cagctatacc tgctgttaca
   103621 aaacctataa ttataaatgg tataacaaat tttaggaatg ctgagaataa agtactaact
   103681 gttactaata tttgtacgat tatttctggt gcataacttc cgattaaaat accgactatg
   103741 ataccgatga ttagtttggg cactaaacct atttttttct tcataatatt taccctccat
   103801 aactttttta aattaagcat tcttgtacat tgaatactta gttaaatatt ggatatccac
   103861 ttattatgat aatagagttt tacctctccg tcaacaattt aaccattttt tgttaataaa
   103921 aaaaagaata acatatataa agtgttcctt ttatttattt tattttatat atatgtctat
   103981 tttcaatatt ttataatgtt gatactcttt atttttttaa ctttcgtcag ttgaatgtca
   104041 gtaaaatatt ttatccacat atttcatata gttttcccac aacttatccc cgatattatt
   104101 tataaacaaa aagatagata ctagtaactc tgttttaact agtatctatt aaggtataca
   104161 ccaaatatat tagaacttaa ttatgataaa tataaaacca aaggagaata aacatatgac
   104221 taaaactatg atatgtgatt attgcaataa agtaataaat aataatagtg aatacattac
   104281 ttttcataag aaaaactatg taaaaactag tgtatgtatt aattgtgtgt taaaattaat
   104341 ggacaaaact aaagaaaata agtaataaac aatattattt gagaaagtga agaaaacact
   104401 ctaccataag gaaaatgctc tatctaatat aaatatggta aaaaagtaaa gatgtattgg
   104461 gcgtacatct ttactttttt accatatcac attactaccc taataaaaac agctttatgt
   104521 acaaaaacac catttaaaaa ggatgttttc ttggataata ttgttttaac tagtaaagat
   104581 atattgaggg gttatcttta ccttttttat tatattataa atttcctaaa agtaaaatta
   104641 taattaaaat atgtataaat tacaataatt agtaaactat cttttattat ttagaatcac
   104701 ttgttacatc tggtgctgta tcagttgaat tttcctgtcc atcagtaata cttttttctg
   104761 ctttattttt agttgtatca ttgttttctt tatcaccaca acctacaacc ccaatagata
   104821 ctaaacaagc aagtattagg acagtaactt tcccttttaa tctcatcttt atcatcctcc
   104881 tagataaata ttaattcact atttaaaatt atagcaaagt aatgttaatc ttatgtttat
   104941 tgtaaaaaat atgtaattta tatgcttaga atattatatt ttctaacaaa atgtaatata
   105001 gtagaaaata cattaatgaa tttcaaaaaa taagcactca tataaagagt actttagtgt
   105061 atattaatga atgtttataa tctaatttaa catgtcttat gttttagtat gataattttc
   105121 gttcgcttta ttattacaac ttatgttcta gttttatgta tcctgctaat atttgtaata
   105181 ttttagatac gctttatgct tatgttgctg atatactttg attaagaaaa aaaatctaat
   105241 ataaactggt gattatatta taaaggaggt atctactatg aattttggaa atattaatct
   105301 tataattatt ggagtaggaa ttataatatt aactacaata atatctttaa ttaaacctaa
   105361 aattagcttt tgtagtgaaa aatattttaa taaattagaa tcaatatatg gaaatataga
   105421 tagaaaaaga actgttaaac tggaagtgct ttctcgatat gtaatgggtc ttgaatatat
   105481 agtaataggt ttattcacaa gaagattaga tattacaata atagcaatga taatagtagc
   105541 cgttataaca acagtattat attatctaat tagaaagaaa tatataacta tataaaatct
   105601 aataaaatta atactagaag aaggtagcaa ctagttacgg ttgctacctt ctaatctatt
   105661 ttactaaatt ttctatttca ctaaa
//
LOCUS       DBGJFK010000005        99351 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.005, whole genome shotgun sequence.
ACCESSION   DBGJFK010000005 DBGJFK010000000
VERSION     DBGJFK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 99351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99351
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.005"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(225..800)
                     /locus_tag="ACOIAP_000421"
     CDS             complement(225..800)
                     /locus_tag="ACOIAP_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HGZ2637341.1"
                     /translation="MQKITWEVEYTSQLPVIRYCKKCGKKTEYVCSGLFRVNAQHKYL
                     DIWLIYKCLNCDSTWNSTIYSRVNPNNLSPEVLEQFHTNDDNLANQYAMNIELLHRNG
                     AEVGIPEYKIVGQEIDINDLTQIRIVSKYPSQLKVSTLLREKLGLSRKVFDEMLDCGT
                     IKSVSGVDLRRSKLNYEIVLEVGKEKQKSSN"
     gene            complement(1095..1373)
                     /locus_tag="ACOIAP_000422"
     CDS             complement(1095..1373)
                     /locus_tag="ACOIAP_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HGZ2637342.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSNTS
                     TREELAIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            complement(1678..2439)
                     /locus_tag="ACOIAP_000423"
     CDS             complement(1678..2439)
                     /locus_tag="ACOIAP_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HGZ2637343.1"
                     /translation="MKNKIETLMNNFVKDYHKFNSITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLKNGKTIITYFIPFDESINNSNIGGFECSEIWARAYIETNMLIS
                     NLNSYLCEELEKIGFDSYAIPGSYNFDSEKLVSDWSQRHVAFISGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDRFDRNKCY
                     EMCTINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(2608..4656)
                     /gene="bclA3"
                     /locus_tag="ACOIAP_000424"
     CDS             complement(2608..4656)
                     /gene="bclA3"
                     /locus_tag="ACOIAP_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HGZ2637344.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNSGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGGTGRGGPT
                     GPTGPTGPTGPTGPIGFGITGPTGATGATGATGADGVTGPTGPTGATGANGITGPTGA
                     TGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGVTGPTGAVGATGIGITGPT
                     GPTGATGADGATGATGPTGATGTTGADGVTGPTGATGATGFGVTGPTGPTGATGVGVT
                     GATGLIGPTGPTGATGLIGPTGVTGATGADGVTGPTGPTGATGADGATGVTGPTGATG
                     ATGADGLVGPTGATGATGADGVTGPTGATGATGVGVTGATGATGATGPTGADGLVGPT
                     GATGNTGADGVAGPTGATGATGNTGADGATGPTGATGNTGADGATGPTGPTGATGVAG
                     VTGATGPTGATGATGADGATGPTGATGATGADGLVGPTGATGATGITGATGVTGPTGP
                     TGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGVSIVGGVIDLTNAAGTLTN
                     FAFSMPRAGTITSISAYFSTTAALSIVGSTITITATLYQSTAPNNSFTAVPGATVTLA
                     PPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVEGYASAGISIN
                     "
     gene            complement(4723..5799)
                     /locus_tag="ACOIAP_000425"
     CDS             complement(4723..5799)
                     /locus_tag="ACOIAP_000425"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2637345.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGSPTLSYYRERLFKRSSNHKWVDPIHEVVPLSGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKVLEPRHQFYYSRELYYNAKYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPYIQLSVCYDRLGESNKAIYYHEK
                     TKEIKPNDSAVLHNENYFNKFKNS"
     gene            complement(6102..6686)
                     /gene="clpP"
                     /locus_tag="ACOIAP_000426"
     CDS             complement(6102..6686)
                     /gene="clpP"
                     /locus_tag="ACOIAP_000426"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HGZ2637346.1"
                     /translation="MSLVPHVIEQTSQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSVTAGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRYALPNAEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDRIFSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(6683..7165)
                     /locus_tag="ACOIAP_000427"
     CDS             complement(6683..7165)
                     /locus_tag="ACOIAP_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2637347.1"
                     /translation="MKTNTDVIMEIIDYIEENLTENLNLDKIADIANYSKYHLHRMFT
                     NIVGCTIHQYIQRRRLTEAARQLIFTDKYIIDIAITAGYSTHQSFTLAFRNLYKESPQ
                     VYRNKDEFYPIQQRFVLNLNHQIQSEKYISYANMNCKQRIDEINSYLNFNINCEVKVA
                     "
     gene            complement(7364..8779)
                     /locus_tag="ACOIAP_000428"
     CDS             complement(7364..8779)
                     /locus_tag="ACOIAP_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGZ2637348.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILNGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNYIFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRAEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGVKVDDKGINTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKYATENGYYII
                     EDDYDSEFRYEGQPISSLYELNPNKVIYIGSFSKILSPAIRVGFILLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIEKILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHINQGT"
     gene            8894..9562
                     /locus_tag="ACOIAP_000429"
     CDS             8894..9562
                     /locus_tag="ACOIAP_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HGZ2637349.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLILKNSTIKN
                     IIEKHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKIELPLKIDLANGSEHFYGIGAKEQILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKYYISSAFPDLKINS
                     IDIF"
     gene            complement(9753..10271)
                     /locus_tag="ACOIAP_000430"
     CDS             complement(9753..10271)
                     /locus_tag="ACOIAP_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2637350.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLDKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGLNKLSKAANIYDAPLAILVCGDKEKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKVADSPDRHEKTR
                     VPLSEIVSYEIL"
     gene            10423..10746
                     /locus_tag="ACOIAP_000431"
     CDS             10423..10746
                     /locus_tag="ACOIAP_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGZ2637351.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLEKL"
     gene            complement(10751..11077)
                     /locus_tag="ACOIAP_000432"
     CDS             complement(10751..11077)
                     /locus_tag="ACOIAP_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HGZ2637352.1"
                     /translation="MSSYLNLIREFNLKEKIIAFICVSALLIGKSCVLKNRKATTYHL
                     KNSKRQRQLSEFDVNVVNEPTVVNQNIITSYYTETAPHVAFKLLEMLISKKQLDEVKL
                     AMGFKL"
     gene            complement(11062..11286)
                     /locus_tag="ACOIAP_000433"
     CDS             complement(11062..11286)
                     /locus_tag="ACOIAP_000433"
                     /inference="COORDINATES: protein motif:HMM:NF013209.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HGZ2637353.1"
                     /translation="MSRKINLSIPAVSEHIRKIEQLNLIQKYTIQINQEKIKYKLLAF
                     VFINTDLSKSMEEFKKTILEYDTALECHHI"
     gene            12359..13897
                     /locus_tag="ACOIAP_000434"
     CDS             12359..13897
                     /locus_tag="ACOIAP_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGZ2637354.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVIPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQESAISGNEQHLIKASDYQEQLIANNFYSIDNEVNKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHEVLLLDEPTNFLDKEHVEWLSNYLNTFSGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKLHLREDYIRRYQSQQKKIEKEEAFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPGFTGKPNIKFSEIEISAQNALTVTNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPCISGDFQFSEQVKLAYYEQDL
                     KWENPTKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLFPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(14174..15004)
                     /locus_tag="ACOIAP_000435"
     CDS             complement(14174..15004)
                     /locus_tag="ACOIAP_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637355.1"
                     /translation="MYIRDVTISNVKARVVNIKKQDSDTARLEYNKFLWRDFNMDTYF
                     NKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAISLCKIACPDVVILDIMLPD
                     IDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGDDYITKPFSPREIVFRVKAQ
                     LRRQQYQSIVPSDSSVIKIGDITIDIEGNRVYKDRKEIELTGREYHLLSYMAQNVNKI
                     IGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSNPKILITVKGLGYKLVNRID
                     "
     gene            complement(15337..16716)
                     /locus_tag="ACOIAP_000436"
     CDS             complement(15337..16716)
                     /locus_tag="ACOIAP_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2637356.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCHSYIFIILIFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGVLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLISEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNMLNINGIWLAVPSAEILTLFLTVFCIC
                     KHKNRYKYM"
     gene            complement(16999..17793)
                     /locus_tag="ACOIAP_000437"
     CDS             complement(16999..17793)
                     /locus_tag="ACOIAP_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HGZ2637357.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPIDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVIIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFSFTLFMWRFWKLGLRHYKSASS"
     gene            complement(17790..18644)
                     /locus_tag="ACOIAP_000438"
     CDS             complement(17790..18644)
                     /locus_tag="ACOIAP_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637358.1"
                     /translation="MSNYNEASSNSSMFYKFKQSIRRYYEVAKINFKVQLIWRFDVVV
                     NMMFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLSGIDMSKSTSEEIC
                     NRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKINFAFTSNP
                     IQILISIFMIFLGLIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPLVLL
                     PETIVKVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYKRMR
                     TLFDGVGI"
     gene            complement(18631..19626)
                     /locus_tag="ACOIAP_000439"
     CDS             complement(18631..19626)
                     /locus_tag="ACOIAP_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2637359.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFIGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAIV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSEYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAVAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEELFNHFQKYKKITVSFSNETNIVFSKDCKVVEQT
                     NHKTSVVVPKERGNETIKWIFDRYDVKDVMIEEEDIVNIVERIYKKGSDEYYEQL"
     gene            20329..21285
                     /locus_tag="ACOIAP_000440"
     CDS             20329..21285
                     /locus_tag="ACOIAP_000440"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2637360.1"
                     /translation="MKNNTTQKRLRDLSKKIWNIYILNPEEEGIKFIISLLDDNLTLI
                     GTGKHEFYETLEEFIIGLEKDQVESNQIDFEIIDEWYSCTKVTDETFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVKDDIIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHI
                     RGDEILIHFSNILTKVFISDAIIGRLGGDEFAVFEYSNQSKEDVENKAKKVLELCLEN
                     NSCSIGISRLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(21864..22562)
                     /locus_tag="ACOIAP_000441"
     CDS             complement(21864..22562)
                     /locus_tag="ACOIAP_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637361.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESIVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKDRQEVYTKKINEAIKNLYKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLYENSTYLNTSDEKESLITKEFNEKVEEEMLNDEKLEELEQKKDYKEDSNKK
                     EKISEDLSLAGKTREELENMLKNFTNLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLL"
     gene            complement(23105..24172)
                     /gene="rsgA"
                     /locus_tag="ACOIAP_000442"
     CDS             complement(23105..24172)
                     /gene="rsgA"
                     /locus_tag="ACOIAP_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGZ2637362.1"
                     /translation="MNGMKEIDLQDYGLNSNFITQSMKYHDLYIARIISQEKNLYQAV
                     CTGGIVFAEVSGKLRFEATIPSDFPTVGDFVILDRCNDKNGNAIIHHVLHRKSLFVRK
                     AAGKANEEQVVAANIDIVFLCMSLNKDFNTHRLERYLSLTWESGAVPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSAKESDGCQQISKYIKPGYTIALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIADDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGVDKS
                     FADIEAYFGKCHFRNCSHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
     gene            complement(24169..24570)
                     /locus_tag="ACOIAP_000443"
     CDS             complement(24169..24570)
                     /locus_tag="ACOIAP_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HGZ2637363.1"
                     /translation="MNYKNRKRAYYQENSCLDNFICKNCGCIVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNP
                     VKLMSIALKPLAQPPFPLERITEKMEKEETE"
     regulatory      25364..25460
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            25513..25689
                     /locus_tag="ACOIAP_000444"
     CDS             25513..25689
                     /locus_tag="ACOIAP_000444"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637364.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            26099..26236
                     /locus_tag="ACOIAP_000445"
     CDS             26099..26236
                     /locus_tag="ACOIAP_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637365.1"
                     /translation="MSNQREDFDTTNDMFQESIPITTKIILDDIPSHDELNHVFSKGC
                     E"
     gene            26240..26737
                     /locus_tag="ACOIAP_000446"
     CDS             26240..26737
                     /locus_tag="ACOIAP_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637366.1"
                     /translation="MKKRKIVLITLLLIGVLLLGGILYNLFLVKTANISMLKESWNLD
                     IPIPNKEIEVFDTQDSINGDGQSYFIQEFSEKNFKKVFNLKGGIVVSKDNINEIEKYI
                     DKFKRDSVNINKSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYS
                     LIWNQ"
     gene            complement(27214..28890)
                     /locus_tag="ACOIAP_000447"
     CDS             complement(27214..28890)
                     /locus_tag="ACOIAP_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637367.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIDGYSLEAQKSRMKAFALYNDYEIV
                     GEYEDAGKSGKSIEGRVQFTRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDFGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRVQTMEGRIQKAKEGKWNG
                     GFAPYGYQLIDGKLIINEEEAIAIRTIFDQYVNTSIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYRQVEQDDYLVAEGIHEAI
                     IPDELWQAAQVKLKAQAKKYEHVNKGKNMRTHLLSGIVKCPICGAGMFGNKSIKYKKD
                     GTKYKDFYYYGCKHRLMNRGHKCTYNKQIREELLDDAVAEVIIKLVSNPKFASMIQEK
                     INMKVDTSAIENEIDNYQNELRKSHSTKYKLIEEIDNLDVEDKHYKRRKNDLDDRLYR
                     MYDKIEELESQLIEAKAKKETIEVEKLTGDNIYKVLIYFDKLYKVMNDVERRQLIEAL
                     ISEIQIYEEKQPNGQWLKSITFKLPIIDEDLNISLENDEQVETVAKIIKQ"
     gene            complement(28991..29143)
                     /locus_tag="ACOIAP_000448"
     CDS             complement(28991..29143)
                     /locus_tag="ACOIAP_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637368.1"
                     /translation="MDNDWNGLADLIANLITKYAGVLDLENLPNPTPVKNTEDKNKFD
                     IAKSTD"
     gene            complement(29632..30042)
                     /locus_tag="ACOIAP_000449"
     CDS             complement(29632..30042)
                     /locus_tag="ACOIAP_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2637369.1"
                     /translation="MAKEYYLYIRGQKVKVSEDIYIVYWREKEHEKYLEQVDRKNHLL
                     FFSALDHDGHFTDNIVDESVDVEKIVETQMMIEAVRSAITRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
     gene            complement(30566..31885)
                     /locus_tag="ACOIAP_000450"
     CDS             complement(30566..31885)
                     /locus_tag="ACOIAP_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2637370.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLVFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLELYSKSSEIKAFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKTRLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKALQDEEFFIFKIKIFS"
     gene            complement(31882..32535)
                     /locus_tag="ACOIAP_000451"
     CDS             complement(31882..32535)
                     /locus_tag="ACOIAP_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637371.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYNDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            complement(32633..34009)
                     /locus_tag="ACOIAP_000452"
     CDS             complement(32633..34009)
                     /locus_tag="ACOIAP_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637372.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYNIIETQETLANQSPERAKNFKRTVMLTGVNDSSKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDVHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFVGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIARQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFIIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(34009..34665)
                     /locus_tag="ACOIAP_000453"
     CDS             complement(34009..34665)
                     /locus_tag="ACOIAP_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637373.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQKKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(34675..35952)
                     /locus_tag="ACOIAP_000454"
     CDS             complement(34675..35952)
                     /locus_tag="ACOIAP_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637374.1"
                     /translation="MIKNAIAYITRKRNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIGENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNKSENNKIANKILMYSGSAESTDLALNKLKEFKIDESKYFVEKDSNAFEES
                     LESVSGIKHIIKIMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSENSMISGGSLINNSSFMLNITTLGQ
                     SYLILISIIVLSVVFASSLILIKKPKEILSKIS"
     gene            complement(35971..36861)
                     /locus_tag="ACOIAP_000455"
     CDS             complement(35971..36861)
                     /locus_tag="ACOIAP_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2637375.1"
                     /translation="MDRIKNIINGSTKKDKYKIRDRFRHLFQSVWFLITNSYFEGFKT
                     GKIYGGNLKKICVPGMNCYSCPGAKGSCPIGSLQAVIGNSKYKISYYIVGILFFIGAL
                     VGRFVCGWLCPFGLIQDLLHKIPFFKKVETFKFDKHLRKLKYIILLVFVIILPLFLVD
                     ILGQGSPYFCKLICPIGMLEGGLPLVLLNKSMRNAIGFLYYWKGIILIVTLLLSIIIY
                     RPFCKYICPLGAIYSIFNPISIFRYRLDKDKCINCGKCKKVCQMNIDPVENCNHLECI
                     RCGRCKNACPVDAISYGVRK"
     gene            complement(36854..37006)
                     /locus_tag="ACOIAP_000456"
     CDS             complement(36854..37006)
                     /locus_tag="ACOIAP_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1871A family CXXC motif-containing protein"
                     /protein_id="HGZ2637376.1"
                     /translation="MVNKFLKSRALSLLIIFISMAMIYYGHSNGETKVVLDKAIRICM
                     ECIGIG"
     gene            complement(37028..38185)
                     /locus_tag="ACOIAP_000457"
     CDS             complement(37028..38185)
                     /locus_tag="ACOIAP_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HGZ2637377.1"
                     /translation="MKKIVSRGACLLLALCLSLNAVGCQKSNENNKIKEGQSISSEEA
                     GMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSDKFRNYIADKKIAMLDDQSP
                     IDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELERIGTIGIFEKNTSEEKISK
                     ITKCDTHTKIGVSSDGKYDCYLSINSGAESNLLDELKRTEIQIIDKKERPKNGFVLSE
                     KTDLENTEAFNKESVKDLRKLSTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEI
                     PDLVEVQNEMKSKGVNIVGVVTDTVDDNGENKEAIEKSKLIHEKTKASYPFLMPDKTN
                     FNGRLNGIQAMPETFFVDSNGNIVGDTYSGAKSAKEWKQVIEKELEKIKNK"
     gene            38509..38865
                     /gene="mobC"
                     /locus_tag="ACOIAP_000458"
     CDS             38509..38865
                     /gene="mobC"
                     /locus_tag="ACOIAP_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGZ2637378.1"
                     /translation="MANRIRNERLEIKLTEEEKALFEEKRKLSKCRNMSHFIRKCVLE
                     KEIYQVDLEPFRDLQVLLSNATNNINQIAKRVNQTGIIYKDDIHDMKKAIEHFSKELW
                     QIHSLLLKRTSETEGE"
     gene            38868..40199
                     /locus_tag="ACOIAP_000459"
     CDS             38868..40199
                     /locus_tag="ACOIAP_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HGZ2637379.1"
                     /translation="MAITKIHPIKSTLNLAIDYIVNGDKTDEQLLVSTHKCHESTAHT
                     QFLRTRKNVGTKGTVLARHLIQSFLPGETTPEIAHQIGMELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGRCYQSNKKSYHQIRYQSDNLCKENNLSVIDEFYEIYKKK
                     YKTNGKSWYENKQAKHGTSWKSRLQFDIDRIIKQSKDWDEFLKKMADLGYEIKYGKHI
                     AFKSKYKARFTRAKTIGEDYTEERLKERIAEREFIKTPAVKKRIGNVIDTNTNVKVKE
                     SKGYEYWATKHNLNTMAESVIFLREQGIKSVKQLDEYIQKAADERQNLQDKIKVIDKE
                     MQELSAIMEQVHTVKKYRQYYKEYKANPSDKTFFEEYKVQITLYENALSELKKSYSKL
                     PNSRDILSELDKLQEKKNTLMQEYSSSKSIMNELYKIRKNYGIYMGKEMER"
     gene            complement(40221..44003)
                     /locus_tag="ACOIAP_000460"
     CDS             complement(40221..44003)
                     /locus_tag="ACOIAP_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009529170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637380.1"
                     /translation="MLEDVKHNKFNALTPEVLKENKQIYTEALDYAFGNSSIKNIAIT
                     GIYGAGKSTVWNTYVHEKELSNIITVSLGKYKNNIKDDDDILKEVPLTNTLNSESDGA
                     KNKRSNENQKAEDIGDDNRVERQLINQILSQIESKKIPLSKYGFKSNKSILSICLQSL
                     AVLSIICSILLWIIRDNFISFVNESYKNFNGISLMFLCALLLFVPLFYYLYIFNRGNK
                     FKISKITFKGAEANINDNNSDESVLDRDIKELVYLLRSSNSKIVVFEDLDRYDNASIY
                     TKLRELNFLLNKYVKVNDEKETPIRFIYMLKDSLFYSKNRTKFFDFILPIVPVVDSKT
                     SENELIELLKEVENAPDRSLLADISLYVDDMRLLKNIVNEYIVYSKIIPIGKIDLESN
                     KLFALITLKNIFPNEFDLLQEDKGFVRAIFDELESNRKKIVSNFKQDLEKIDDNIKFI
                     NSRIANDKFEAMALMISTDVRPYNNQSKTMSQFLKDWSQNPDNRFDIKYPSGSQYFTY
                     NDFLNRYVLTDNEKKALVEKLPEDFSVEMNKLNLDREKIKKQIKDIEIYSYKELISKM
                     NTEQRDKLFSIDGFDIVESHYFPLIRFLIVDGLLDETYWYYKGNFNVDTSNILKRNDM
                     IYMKGLKEGKALDIFLDVETPNEIISRLKLSDFSRFNILNKKVLKTCLEQKQTENVVA
                     IVDSVDINDKYKDLLKILDEFDLDIVRIYSNMLLKNNVDRLVRTLEFCEDENIDTFKN
                     ILISVLTNKTIDLANLAEFKEYIEQNENIISLIPEEEFNVFIDNIRSAGIEFEDVSEA
                     NCDKVRLAGVEQVHAYKLNVRNLLFITEAILEKTINYGSLLSEIYNSSQLSSSKEYIE
                     DNFSIVISDYIDENKSEKNYTNSEEILLRILNSDISDEYKLEYVEKNETAISKLTDLQ
                     DNSVTTRILDCLLRKNKVKFCSDNIASYWNMIEEYSDDFVEYLNDNLDEDNNEDILKN
                     NISVCNTFINSSFVSDKIFAFVIKYADEPISNVNHKLTQNRVNTLVHQRLIEVTEKNI
                     ETLWNNSYYAELISLANYDDDVAEGLVINMLLKYELSDELIYGLVNSDIADGNSMKLI
                     DSIKDSVLVEKINPTKKPIIEYIIKGDLSSVNINYICKSFKMFELKDEFIKSLDDEDK
                     LEDLEDENLNEVFMQYVLSSPDIKLSTKVSLVLTKIKNGLSVNVLKGYISSVKEISEL
                     SNVWENKQPLLDNSYKDKVGQALIKFGYVKLRKNKDYPRIMLSRRQNKTKIDDYLL"
     gene            complement(44013..44219)
                     /locus_tag="ACOIAP_000461"
     CDS             complement(44013..44219)
                     /locus_tag="ACOIAP_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006906964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637381.1"
                     /translation="MKFNYNRLWKLLIDKNMKKKDLIERTGISPTTIAKMAKGEAVSL
                     SVLGKICKELNSDIGDLICLDKER"
     gene            complement(44342..45001)
                     /locus_tag="ACOIAP_000462"
     CDS             complement(44342..45001)
                     /locus_tag="ACOIAP_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGZ2637382.1"
                     /translation="MDYKTMRNQIEDMVNDNHKDFVKAIISMEKGINDESVLDKLYDA
                     YMDNDSLNLMHEEFDYMIEDLREQGQIKNLPYVQEEKDNLINIVGNIVGEVDVVEREN
                     KNEEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTAIDD
                     NGKEYSNIRILSSKLLKAKEQMKGREERKESVLGAIKKYQAEDKEKPKEKKEANREAE
                     R"
     gene            complement(45044..53772)
                     /locus_tag="ACOIAP_000463"
                     /pseudo
     CDS             complement(45044..53772)
                     /locus_tag="ACOIAP_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-related protein"
     gene            complement(53855..54658)
                     /locus_tag="ACOIAP_000464"
     CDS             complement(53855..54658)
                     /locus_tag="ACOIAP_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HGZ2637383.1"
                     /translation="MSKINVEGSEISIIAIDNRDYISLTDMVRNIENGSALIEKWLRN
                     KNTIEFLGIWEEMYNTNFNSPEFEGIKNEAGFNRFILSVKQWVEKTNSIGIVARAGRY
                     GGTYAHKDIAFEFASWVSPYFKLYLIKEFERLKEEEQKKLGWDIKRNLAKINYRIHTD
                     AIKNKLVPDKLSKEKINFIYASEADILNVSLFGITAKEWRDENPDLKGNIRDYADISQ
                     LVCLSNLENLNAVFINEGMSQSERLEKLNAIAIEQMKILSESESIKKLK"
     gene            complement(54743..56449)
                     /locus_tag="ACOIAP_000465"
     CDS             complement(54743..56449)
                     /locus_tag="ACOIAP_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HGZ2637384.1"
                     /translation="MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLI
                     QMANPDAYDEKYAKWNMADLPIIPSDYKYEVAKATKKQFNILKKLMNDKEVDTVINAC
                     DAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDNLTDGKDYDNLFESAQA
                     RAIADWLVGMNISRLYSCLYQQNYSVGRVQTPTLAMIVKRDDEIANYQKEKYYTVELS
                     MNGFTLSTDRIDDEVAAEQLISLVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKY
                     FGYSAKQTLDYTQSLYEKKLITYPRTDSRCLTEDMIVSTVNNILGKNDFDTERIKVVF
                     NSKKVTDHHAIIPTISSVKEDVSELPLSEAKVYFLISDKFHASVGYPLIENTTKIVAS
                     FDGFEFTSSGKVIKDEGFSKYLKEYKSKKSEDAVLPDVSVGEVLSVENKEVKEKFTQP
                     PKHFTEDTLLKSMEIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKRFVERDKKNL
                     IATNKGISLVTIVADTFKSAETTAKWEMELSDIAQGKSSKKEFLDAIENEIKEAVLTY
                     RK"
     gene            complement(56544..58085)
                     /locus_tag="ACOIAP_000466"
     CDS             complement(56544..58085)
                     /locus_tag="ACOIAP_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HGZ2637385.1"
                     /translation="MKTSLKKNNKFWTVALAVIVSISCILGLWTVVYAQEQKSEAPTK
                     NEAVQTEVEVNVRYIFEDEKVFKEEKIKAEKGQLIDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGKDEIIRKVAKMEVKDKETQTEEEKPKQDECTQTEDKGTQTELSKDDISKIEKEA
                     KELQDKLDKLNCELKDKDKLSDKQKNKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKKE
                     IDKLTEKVKELEKKATETNKAPVTSQSVTPISPISGIKTSSGISPQTPQTSVSSTGKG
                     SSDSVSSGNTTKDTGKGKTEVKEKEKEVRYPNKLTAKAPANNSQDSSMGSASKSVNTN
                     KGVASSPSKARASVTENKDNANKEYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEYSENVMLLTEVSEDDLLNMAEKKEAPKQEVVKEEPVKEEVKPEKKDEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSESESEEEINDADE
                     VEDEE"
     gene            complement(58060..58299)
                     /locus_tag="ACOIAP_000467"
     CDS             complement(58060..58299)
                     /locus_tag="ACOIAP_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2637386.1"
                     /translation="MKKELTTVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLIAKVNRQKAEMKKEKTNENQFEKE"
     gene            complement(58311..60443)
                     /locus_tag="ACOIAP_000468"
     CDS             complement(58311..60443)
                     /locus_tag="ACOIAP_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HGZ2637387.1"
                     /translation="MGKKLKKDFKERHKASLEREMFHSKTDTIPEESKLKHNDDYRGK
                     IVHEKERFQDKVHEKTSKVSADNEKSYGTSKRNEKYRTSDKGDVNSAIETGRSDYITE
                     VKDGKIYDPLGKDLDNDGIIDRYDNDFRDSNYFESTYDVEDNLSHKEKSLENSFKNHK
                     TQKSRYKRKNYSESLYTRKKDDAPKGNKADDKKAGKDAVSGKVYSSLSKDQKKKLKKD
                     MVKVSALSGLAKGSETVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKKYSDKKRAK
                     RGYDLTNKDYKIRKRKSKLEFRDAKKELKKTDEYKRASAYKRFQKKNQVKAAISRENK
                     SRLRDRIKEGLIGTLKSSKDMIIRKAKGLMLIFIGIIILGTFVINFAGTGMTGFMNST
                     SSVLTTSYLSKPNVLSEINQKFSDMEGELQSEVDYVKENYPGYDEYILNNTEYIGHNV
                     HELLSYITSRCGEVKSVSEVESILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNE
                     YTESHEEPYEYKKLIVTLHKKEMDSIIRKVFANYPDNLKHYEALFLAQGNMREAFGNS
                     DLISANGGIGGGKEYEASTEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGG
                     NACDMYRNYTFTSDRSKLKVGMLVAVESSSSGSSAGLTYGHVGIYIGDGKVIDNIGRI
                     RVTTLDDWIATFCKHHPVGFGFPPNVKK"
     gene            complement(60447..62876)
                     /locus_tag="ACOIAP_000469"
     CDS             complement(60447..62876)
                     /locus_tag="ACOIAP_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HGZ2637388.1"
                     /translation="MNKKRKIQQIKLMQNEKALRSQKRDLKKSNCKSKKDKGGILDLI
                     FKKEPKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSISIEFSYINQLGRNEEMKSAIQIPDKKDGFDDIRFEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLEIDILSSLKSMGVRAESLNGEERLKILHD
                     VLNPNKTFKFSYKDLKKRESTKTYIVPDEFNFTPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIRAIDQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHSQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYEKYFEHPTPDNMPILQNLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYFVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFIDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(62788..63177)
                     /locus_tag="ACOIAP_000470"
     CDS             complement(62788..63177)
                     /locus_tag="ACOIAP_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HGZ2637389.1"
                     /translation="MAYVPIPKDLNRVKTKVAFNLTKRQLIGFTLAGLVGIPVYLFMR
                     KFVPNDIAVIFLIVSTLPIFFITLFEKDGLTFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     QEKKNSANKTHAKRKGIEKSKAGLKEK"
     gene            complement(63181..63441)
                     /locus_tag="ACOIAP_000471"
     CDS             complement(63181..63441)
                     /locus_tag="ACOIAP_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2637390.1"
                     /translation="MNKRKTVFIVVIGAGIMAIIDRIRLHNKVEELEEKTEDIGRCHN
                     DFYLMQQRYNKNTDEQLATIQEEIGSVYEHFEELSKGKEDGR"
     gene            complement(63459..64322)
                     /locus_tag="ACOIAP_000472"
     CDS             complement(63459..64322)
                     /locus_tag="ACOIAP_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HGZ2637391.1"
                     /translation="MFGIFDKIEEFFKELLLGGIQANLESMFLDINDKVGAVATDVGK
                     TPMGWNGDVFAFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFEFSMAVFDVAQHMVNKAAGVINTSAVISGDQIVKMVDGLKDKG
                     LGELVMILFETSLIKVAIQVISIVIMLVVYGRMFEIYVYSSISAIPFATMGNKEWGQI
                     GTNYIKGLFAIGLQGLFLMVCLGIYAVLVKTIQITDIHTSTFTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            complement(64342..64557)
                     /locus_tag="ACOIAP_000473"
     CDS             complement(64342..64557)
                     /locus_tag="ACOIAP_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HGZ2637392.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLK"
     gene            complement(64561..64872)
                     /locus_tag="ACOIAP_000474"
     CDS             complement(64561..64872)
                     /locus_tag="ACOIAP_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGZ2637393.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGEEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKAEKAEDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(65036..65836)
                     /locus_tag="ACOIAP_000475"
                     /pseudo
     CDS             complement(65036..65836)
                     /locus_tag="ACOIAP_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
     gene            complement(65860..66045)
                     /locus_tag="ACOIAP_000476"
     CDS             complement(65860..66045)
                     /locus_tag="ACOIAP_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HGZ2637394.1"
                     /translation="MHENRNEQNTGTKTIKKIGRATYEVVVHFNENATETMQDKLKRI
                     MLREMEREKDKKAHKND"
     gene            complement(66155..67162)
                     /locus_tag="ACOIAP_000477"
     CDS             complement(66155..67162)
                     /locus_tag="ACOIAP_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HGZ2637395.1"
                     /translation="MAEENKEIVIVDDKTIQEKIYLIRGQKVMLDADLAEIYGYETKN
                     FNRQVKNNAEKFEGEDFMFQLTDEEMVELSRCKNFTLNRGTGRGSNIKYNPYAFTEQG
                     IYMLMTVLRGELAVKQSRALVRTFKQMKDFIIENQDFIGSKELVQIAVQTNQNTKDIA
                     EIKSQMATKEDLKKVMDNFIDPDTYKHFLLMNGDKIEADVAYTKIYKSAKKSIYVIDN
                     YIGLKTLELLRAAKDNVEIIVFSDNVKNKDMLTKNILNDFRKDYPNINLKMKIAGKKY
                     HDRYIAIDYGTDSEAFYLCGASSKDAGNKISSITKIEESSKDMYHTMFGGMLNNKDLK
                     I"
     gene            complement(67234..67557)
                     /locus_tag="ACOIAP_000478"
     CDS             complement(67234..67557)
                     /locus_tag="ACOIAP_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637396.1"
                     /translation="MRIQFTVTDEELEILTKKAIEGGFPSVTEYCKCSSLQENTSYAD
                     LYTTLLNKISSLPKDKEFVLRELIATPPALIGRWFYENVNKGLVKNVEHIGKAEGGVE
                     KYKRI"
     gene            complement(67731..68483)
                     /locus_tag="ACOIAP_000479"
     CDS             complement(67731..68483)
                     /locus_tag="ACOIAP_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004825155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGZ2637397.1"
                     /translation="MADNRRYYWLKLKEDFFTDKRIKRLRKISGGDTYTIIYLKLLLL
                     SLKDSGKLYYDGVETDFIKEIALTIDETEDDVMVTVNYIIAQGLMEIITENDEYFLTE
                     IPSLIGSETASTRRSRKSRGQKALQCNTGATPCNLLQQNCNGDIEIDKEIDIELEKEG
                     EIEKISPNLYGEYKNVSLTDEEYGKLKDKMQGHRDKMIEKLSTYMQSTGRNYKDHYAT
                     LVHWYEQDKGKLKESSKSKVYTFEDYDKGEHL"
     gene            complement(68486..70138)
                     /gene="mobQ"
                     /locus_tag="ACOIAP_000480"
     CDS             complement(68486..70138)
                     /gene="mobQ"
                     /locus_tag="ACOIAP_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019595625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HGZ2637398.1"
                     /translation="MAETFHFNISMISRGKSKSAVASAAYISCEKIKNEWDGEVHDYH
                     NKKGLLHSEIFLPENVPIALKDRTTLWNSVELNEKASNAQLARNFIIALPKELSFEEN
                     KKLITDFIQEHFVSKGMIADLAIHDGNDEENNNIHAHIMTTLRPINKKGEWLAKSKKE
                     YVLDEKGEKIKLKSGNYKTRKVELTDWNDKGNAEKWRKNFATLCNQYLEKNHQEKRVD
                     HRSYKRQGIEEIPTIHMGASASALEKKGIETDKGNINREIKKHNSLVKAIKNKIKEIT
                     SWIDSLLGNLQAKYDEYKQTKKDELENKAELFNLYEYISIYNEIQGEKTKNLSYYGQI
                     KKGNADLKRFVKAIYYLKDNHLQTIADLQGKVFELAKQSKKISGDIQDKTQRIKDLNQ
                     CVSCIDAIRENKEVYQEYKSKTLFKDSFYNSHKKEIDRYQRARKIIEKFTGTSAIKSS
                     DWQKEISSLENQIQELTKDKAKVQDEFKQIDHIKYAVKIVNEEYGIDLSIEIDKAIKR
                     GDKPSVIAQLKKFQEQEEIKGQYKQKAKEKAKENYKNKGEER"
     gene            complement(70383..70712)
                     /locus_tag="ACOIAP_000481"
     CDS             complement(70383..70712)
                     /locus_tag="ACOIAP_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGZ2637399.1"
                     /translation="MKKENTLQEVQEQISELQQEREKCDVKLKQLQNQGKKLEKLANE
                     KERKRRNHRLIQRGLIVERVIKNPIMFTNDEIEELLKVATHTKEYRQAYEEMINGKDM
                     EDETEIE"
     gene            complement(70797..71213)
                     /locus_tag="ACOIAP_000482"
     CDS             complement(70797..71213)
                     /locus_tag="ACOIAP_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2637400.1"
                     /translation="MDKKEYYLYVKGKAVPVSEEVYKAYWKITEHEKYLQRKDWKHNV
                     IPFSALDHDGHFVDNIIDEKIDLEKIVEVKMRIEELHRALNTLSKEERELMEAIFYKE
                     ESLRSISRREKVTHQAISGRRDRILEKLRKILEDKI"
     gene            complement(71479..72063)
                     /locus_tag="ACOIAP_000483"
     CDS             complement(71479..72063)
                     /locus_tag="ACOIAP_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGZ2637401.1"
                     /translation="MKNKLNGRDFITIGIFNAIGIVIYMAVAFAMATTVIGGFIASGV
                     SFMVAATVYILMALKVKKKGVFTISGTLLGLIALSGGHLPHAVFAVIGGIICDLIIGN
                     YESKGRMIIGYGTFALADFLGTVIPVILFGTASFVERASKWKMSEAQINEALSYFKVS
                     WAVGFGLITFVLACIGAFVATKILKKHFEKAGVI"
     gene            complement(72074..72778)
                     /locus_tag="ACOIAP_000484"
     CDS             complement(72074..72778)
                     /locus_tag="ACOIAP_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009428128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGZ2637402.1"
                     /translation="MIDRKTVDPRIKLILLPIASFTSFFISDTILLFGLIVFAFFLYV
                     YSSMWKRALRFILFFVLLYCIELGLGKFREASIVFAIYMFIYFASRMTLIAMFGGYIT
                     KTTSVSEMLEALNRMKVPRSIGIPFSVLLRFVPTIKIELKALKENMKIRGIVTSRFFP
                     LLHPIKYIEYTLVPLLMRMIKISDELSASALIRGLDSDANRVTLTKLRFRWADLLIGL
                     LGALMIALVIVIQKIY"
     gene            complement(72768..74285)
                     /locus_tag="ACOIAP_000485"
     CDS             complement(72768..74285)
                     /locus_tag="ACOIAP_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019034765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637403.1"
                     /translation="MILLKDVSYEWEDGRTALKNVNLEIKKGEFVLISGKSGSGKSTL
                     GSVMNGLIPHYYKGKMQGEAFASGKDISKLSLHEIGHIVGTVFQDPRSQFFTTTTDEE
                     IAFGLQTICKSRDEIKQRVAEVYAELDIEELEGKSVFELSSGQKQKIAIASIYAMNPK
                     VLILDEPSANLDMKATFDLFLILEKLKKKGTTVVLIEHRLYYVKSLFDRFLLVKDGEI
                     ALDLSREEVIHLEEEFWDENGLRTLELEEYRISEKKDSYQLKDESISGKGLRFCYSNV
                     AKNGKKQKQYILNHLDFNMECGKAIGLIGLNGTGKTTFARVLSGLEKIKEGTIWAGKD
                     KSLNHKDLMDMSYFVFQDSDYQLFSESVLDEMLLGISSKNKKENTQKAKFILNVLGLD
                     KYIDKHPFALSRGEKQRLTIACGMMKQAKVFIYDEPTSGCDKDSMLSVAKLIEEQLKN
                     GTTVLVISHDFEFLANTVSELWVMGDGKIEKVLNMSESNKFLILDKMRGGRELDR"
     gene            complement(74288..75997)
                     /locus_tag="ACOIAP_000486"
     CDS             complement(74288..75997)
                     /locus_tag="ACOIAP_000486"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637404.1"
                     /translation="MFREMLKLLTKTGKRDLIISSVFFALYGLSSIAMIVIVFSILFQ
                     IFDGTSLASLYKGFIAIGLLVVFKGICNMVADMKKHSAGFDIVQQIRERMIIKLKKFS
                     LGFYTNERLGEINTILHKDVDNMSLVVGHMWSRMFGDFLIGAVVFIGLASIDFKLAIL
                     MAVSVPIALVFLYLTIKQSERIENQNNSALLDMVSLFVEYVRGIPVLKSFSNNKSLDN
                     ELMNKTKKFGETSKVASRFKAKQLSIFGFLLDIGYLVLLIAGAILVIKGSLDVLNFII
                     FAVISKEFYKPFASMEQHYMNYVSAVDSYERLSRILYADVIPDKVNGIVPKDNDIAFD
                     NIGFSYEKDEFKMEKLSFSIAEKTMTALVGESGSGKTTITNLLLRFYDVHKGKITLGG
                     IDIRDIPYDELLDRISIVMQNVQLFDNTIEENIRVGKKGATKEEIIEAAKKARIHDFI
                     MSLPKGYETDIGENGGILSGGQRQRISIARAFLKDAPILILDEMTSNVDPVNESLIQD
                     AITELAKNRTVLVVAHHLKTIQKADQILVFQKGNLLEKGKHGELLAKNGYYTKLWKAQ
                     YGV"
     gene            complement(75990..77729)
                     /locus_tag="ACOIAP_000487"
     CDS             complement(75990..77729)
                     /locus_tag="ACOIAP_000487"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637405.1"
                     /translation="MPEKELRKKVIGKNSLSNSLLALKIVFDLIPQILLVYLISSLIT
                     NNINEGNLKYIFLGIFISFVLKGVFYYFATKVAHEKAYEKLTELRLDIIGHLKKLSLG
                     FFKEHNTGELTNIVQHDVEQVEVYLAHGLPEIMAVTLLPTIIFVAMIFVDWRLALGMI
                     AGVPLMYLVKVLSQKTMDKNFAIYFNHENKMREELMEYVKNISVIKAFAKEEEISERT
                     LKTARKYIYWVKKSMGAITIPMGLIDIFMEIGVVIVMILGSIFLYYGNITTPNFILAI
                     ILSSAFTASISKTATLQHFSIVFKEALKAIGKVLTVPLPKKKTEQGLEFGNIEFKDVN
                     FAYGKDSFELKNINLNFKKNSLNAFVGASGCGKSTVSNLLMGFWDADEGQILINGKDI
                     KEYSQENISMLIGSVQQEIILFDLSIFENIAIGKLNATKEEVIEAAKKARCHDFISAL
                     PNGYETRVGEMGVKLSGGEKQRISIARMILKNAPILILDEAMAAVDSENERLIGEAID
                     DLSKDKTIITIAHHLNTIRDSDQIIVMDKGVVLDAGSHEELMKRCEFYKDMVEAQNKV
                     DRWNLKEVVTENV"
     gene            complement(77870..78388)
                     /locus_tag="ACOIAP_000488"
     CDS             complement(77870..78388)
                     /locus_tag="ACOIAP_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGZ2637406.1"
                     /translation="MKIYKDKEELKSEINKSFEKYISEFDIIPESLKDKRVPEVDRTP
                     AENLAYQLGWTTLVLKWEKDEKNGFEVKTPSDMFKWNQLGELYQWFTDTYAHLSIEEL
                     KKRLKENIISIYTMIDTLSEEELFQPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(78439..79011)
                     /locus_tag="ACOIAP_000489"
     CDS             complement(78439..79011)
                     /locus_tag="ACOIAP_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007392010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HGZ2637407.1"
                     /translation="MAQVLKEEVRNRILEAAEKVFYKKDYRGAKLTEIAKEADIPVAL
                     IYTYFKNKAVLFDAVVSSVYINFESAFNEEESLEKGSASERFDEVGENYIHELLKDRK
                     KLIILMDKSSGTKHTEAKQKLISQMQVHIEVSLKRQSKQEYDPMLAHILASNFTEGLL
                     EIARHYQSEKWAKDMLKLIAKCYYKGVESL"
     gene            complement(79087..80925)
                     /locus_tag="ACOIAP_000490"
     CDS             complement(79087..80925)
                     /locus_tag="ACOIAP_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001243444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HGZ2637408.1"
                     /translation="MRNFEKITALYERLSRDDELQGESNSIINQKKILEEYASKNNLS
                     NIIHFTDDGISGTQFDRPGFMAMMNGVNQGNIGCIIVKDMSRLGRDYLKVGQCMEILR
                     QKGVRLIAINDNVDSFYREDDFTPFRNIMNEWYARDTSRKIQSTFRSKGESGKHTAST
                     PPYGYIKDEKDKNKWIVDEKAAEIVRRIFNLTMQGNGPYRIAKILESEKVDIPAYHQQ
                     KLGYGLYQSKNFEHPYRWCSSTIASILKKQEYLGHTVNFKTRKHFKDKKSKYVSEDNW
                     LIFENTHEPIIDQETFDNVQRIRGNVKRYPDGWGEYHPLTGLMYCADCGSKMYVHRTS
                     NYKNIPYYTCSAYTKTPCGMLCPSAHRIKAEVVLNLIQDTLKDIKKYLDEDNEAFICS
                     IQNEMEEKEKIEIEKKKVRLTESQNRLRELERLMCRIYEDMILNKIPNSRYEILNNQY
                     ETEQITLSKEIKDLEQQVSRYEKETDRARKFISLISRYENFDELTTTMINEFVEKIIV
                     HERDRKGSQTSKQKIEIYFNFIGNYELPQAELSEEKKQKLEEEERKIEERKDKLHQNY
                     LKRKASGKQKEYEDKYKARREQKKQEKIKVLKRVGIPVSEYIKTNI"
     gene            complement(80965..82008)
                     /locus_tag="ACOIAP_000491"
     CDS             complement(80965..82008)
                     /locus_tag="ACOIAP_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HGZ2637409.1"
                     /translation="MIDKILKDIKGLCKVQDKVKFLKQNIPYLAFFYVGNIFSHHVRV
                     YVGGDIIDKIFQGILEINTMSFLPSIHPTDILMGVVVAVLIKIIVYTKGKNAKKFRQG
                     KEYGSARWGTKKDIEPYMDEKFQNNILLTQTERLTMNGRPANPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVLECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKSGEDFWVKAEKLYYTALIGYIFYEAPREEK
                     NFATLLDMIDASEVREDNETYMNPIDRLFEALEKKEPTHFAVKQYKKYKLAAGVIELR
                     RTLNHYFSEICTS"
     gene            complement(82005..82490)
                     /locus_tag="ACOIAP_000492"
     CDS             complement(82005..82490)
                     /locus_tag="ACOIAP_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGZ2637410.1"
                     /translation="MINEEIARKTLNMEINAGKVTGKGLLNLLKKLMKEAEKFGGLEK
                     LVNVNGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKNKETGKNSVF
                     FQAKDMKVMDKAFKHVLSKSEKKAERKESIHKNIEKFKEMAKNSISKEKIKNKQKEQS
                     L"
     gene            complement(82492..83502)
                     /locus_tag="ACOIAP_000493"
     CDS             complement(82492..83502)
                     /locus_tag="ACOIAP_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HGZ2637411.1"
                     /translation="MYLFDEQPIVANKTLARELGLNEALVLQQINYWIEINKKSGKNY
                     HNGKYWTYNSIRAWQENDFDYMSFDTVKRTFSKLEKAGYLLVGNYNKDPRDKTKWYTI
                     NNDKLEELYMDMDLKKQKIQTEALKNSMPNALGQNAPMDKGKINQCNNADCTNAQVQN
                     ALMQKDNLHQPLPENTTNNTTNNSAYISIHPSIKEKNQLFSENMKGGRIDISYKNIYQ
                     NCLEELRHQTGYYEHMSIGNKSVAEEFDEILKILADVMVLDDESFITINQTKISVQVV
                     KERFRKLNSGHLEYLVGVLRENEYKIRNIRAFVLTAAYNAPSGIDAYYSALVSYDMRG
                     GY"
     gene            complement(83603..84121)
                     /locus_tag="ACOIAP_000494"
     CDS             complement(83603..84121)
                     /locus_tag="ACOIAP_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGZ2637412.1"
                     /translation="MRVYENKEELKTEINKTFEKCIVEFDNIPESLKDKRIDEVDRTP
                     AENLAYQVGWTTLVLKWEEDERNGLQVKTPSDEFKWNQLGELYQWFTDTYAYLSLQEL
                     KSKLNENINSIYVMIDSLSDEELFKPHMRKWADDATKTAVWEVYKFIHVNTVAPFKTF
                     RNKIRKWKKIVL"
     gene            complement(84162..84443)
                     /locus_tag="ACOIAP_000495"
     CDS             complement(84162..84443)
                     /locus_tag="ACOIAP_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
                     /protein_id="HGZ2637413.1"
                     /translation="MRWILKIILFPISLLLSILTAVLSFLLGIGTVILYLLMIFCIFG
                     AIASFLQKEVTIGIEALIIGFLLSPYGIPMVGASIIALLQGINEKIMSV"
     gene            complement(84756..86096)
                     /gene="rlmD"
                     /locus_tag="ACOIAP_000496"
                     /pseudo
     CDS             complement(84756..86096)
                     /gene="rlmD"
                     /locus_tag="ACOIAP_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
     gene            complement(86271..88031)
                     /gene="pyk"
                     /locus_tag="ACOIAP_000497"
     CDS             complement(86271..88031)
                     /gene="pyk"
                     /locus_tag="ACOIAP_000497"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGZ2637414.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIICVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRVIKNGDTCVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(88083..89042)
                     /gene="pfkA"
                     /locus_tag="ACOIAP_000498"
     CDS             complement(88083..89042)
                     /gene="pfkA"
                     /locus_tag="ACOIAP_000498"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGZ2637415.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFVGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(89251..92820)
                     /locus_tag="ACOIAP_000499"
     CDS             complement(89251..92820)
                     /locus_tag="ACOIAP_000499"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGZ2637416.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     FDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSDEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKIAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFLE
                     LEDLYGAIEIVVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFVDRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(92965..93918)
                     /gene="whiA"
                     /locus_tag="ACOIAP_000500"
     CDS             complement(92965..93918)
                     /gene="whiA"
                     /locus_tag="ACOIAP_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGZ2637417.1"
                     /translation="MSFSTETKNELARVVSGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILENKEGFFTINKISDNLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKSSQ"
     gene            complement(93935..94360)
                     /locus_tag="ACOIAP_000501"
     CDS             complement(93935..94360)
                     /locus_tag="ACOIAP_000501"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGZ2637418.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(94429..95535)
                     /gene="yvcK"
                     /locus_tag="ACOIAP_000502"
     CDS             complement(94429..95535)
                     /gene="yvcK"
                     /locus_tag="ACOIAP_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HGZ2637419.1"
                     /translation="MAKLLIIVGILGWIALIISLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDKNLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(95547..96404)
                     /gene="rapZ"
                     /locus_tag="ACOIAP_000503"
     CDS             complement(95547..96404)
                     /gene="rapZ"
                     /locus_tag="ACOIAP_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGZ2637420.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(96435..97148)
                     /locus_tag="ACOIAP_000504"
     CDS             complement(96435..97148)
                     /locus_tag="ACOIAP_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HGZ2637421.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYNDINILLGMECNILDDKGNIDMDDKFIRYFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVANAISNNDIFIITHPGDKGDV
                     YIEEIAKTAKKTDTRLEINSSHSFLNLNQLNEIKGLENKFIIGSDAHCPERVGDFELA
                     IKTISDSNLDISLVENIII"
     gene            complement(97152..98066)
                     /gene="murB"
                     /locus_tag="ACOIAP_000505"
     CDS             complement(97152..98066)
                     /gene="murB"
                     /locus_tag="ACOIAP_000505"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGZ2637422.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRVMDM
                     EGNIFELSNKQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(98339..99109)
                     /locus_tag="ACOIAP_000506"
     CDS             complement(98339..99109)
                     /locus_tag="ACOIAP_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGZ2637423.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMSTASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSMVVGGIYYLCYVKNS"
BASE COUNT        30040 a        18956 c        12310 g        38045 t
ORIGIN      
        1 atttaacctt ataccatcta accaattttt tctactttcg taactttcac acttaggttt
       61 atttcattct tatgttttag tttggttagc tttaggggtt tttagcaatt caagtagtat
      121 tggataggtt ctatcctatc tctacatata ggtttcccta tatgctgact attttagcta
      181 ctaactcatg actaaagtca cgagtatgcg tagctatttt ttaatcaatt tgaagacttt
      241 tgcttctcct tgcctacctc taacacaatt tcataattta atttacttct ccttaaatca
      301 actccagata cacttttaat agtcccacaa tctaacattt catcaaatac tttcctagat
      361 aaacctaatt tttcacgtaa taatgttgat acctttaatt gagatggata cttacttaca
      421 atacgaattt gtgtaaggtc attaatatca atttcttgtc ctactatttt atattctgga
      481 ataccaacct ctgctccatt tctatgtaaa agttctatat tcatagcata ttgattagcg
      541 agattatcat catttgtatg gaattgttct agtacttctg gacttaaatt atttggattg
      601 acacgagaat atatagttga gttccatgtt gagtcacagt ttaaacactt atatattagc
      661 catatatcca aatatttatg ttgagcatta actctaaata aacctgaaca tacatattca
      721 gtcttttttc cacatttttt acaataccta attactggta attgagaggt gtactccacc
      781 tcccaagtaa ttttttgcat aaatataatt tcctttctat aaagttacta aactaataga
      841 aagttatgaa aaggtggaat ataatcaagt atttttttca aaacaagacc tcctagtttt
      901 tgataaattt taatttcata catataaaaa gctattatct cttatatatg cactttacaa
      961 ctctattgct tatctgttgt ataagttatt gaaattactt aaattataac atctacttat
     1021 aggaaactat acctcaaaca cttttatcaa aagaaaatga gccagtataa ttataaaact
     1081 atactggctc atccttagat atcttttctt ttttcttgta atacaattct ttggatactt
     1141 ttcaaagata aataatactt ttccgataaa tattgcaaat catatccaac ttgatagtct
     1201 tcgtaaatct gcatatttct aattgctaac tcttcacgag tagaagtatt gcttccccat
     1261 tcttttttat tattagattt tctaggaata tagatatatt caccatctac atattcctgt
     1321 atcagttcaa gtaattcttc tggtaatata tgtattgcct ttttatagct cattttgctc
     1381 tcctattaaa tagtaatttt ttattaggaa tagcaaaggg ctatttatat attaaatttt
     1441 atagttgcaa tagcccttgc tatgcaaaaa taaagattaa atcaaacata aagtctcaac
     1501 cctccttata tatcacagcg atacatataa gtctatcaac agtataaata attgtcaatc
     1561 aatataaatt ggttatctaa cttttaaatt atattttatt taattttata tttattttga
     1621 tagctaaagt tttttcatta taaattatat ttaaaattat taataaacat aaatccatta
     1681 tcttgatggg tttattactg aacaaggaac tccaactata cactttccac aaatatcaca
     1741 tccacctata taagtgtact tcttttcatt tatcgtacac atttcataac acttatttct
     1801 atcaaatcta tcttctttta aagcttcttt tacacattta ttaacacatt ttttgcaact
     1861 attattatgt ttatataaac aatattcatt ttctggtctt ttagttggct ctaattctaa
     1921 acttgtgatt atacttccta tccttccaca acatcctttt tctgtaataa gcatattgtt
     1981 taaaccaaaa gttccaagac ctgatatgaa tgctacgtgt ctttgtgacc aatcactgac
     2041 caacttttca ctatcaaaat tatatgaccc aggaatagca tatgaatcaa atcctatttt
     2101 ctctagttct tcacataaat aactatttaa attcgaaatc aacatattag tttctatata
     2161 cgctcttgcc catatttcag aacattcaaa tcctccaata ttactattgt ttatactttc
     2221 atcaaaaggt ataaaatatg taattatagt ttttccattt ttcagaaaat cttttggcat
     2281 agcatgagat gttccaacaa cactttttaa cttctgaaac atatcatcct cggcagatgc
     2341 ataagcaaac aaaagctctt gccactttgt agttatacta ttaaatttat gataatcttt
     2401 tacaaagttg ttcattaatg tttcaatctt gtttttcaca gtatcccccc tagataattc
     2461 tctatttcta atttaacgtt tttattttat attatataac aatactctat attacgctca
     2521 ctaattaata ttaaaactat gtttatcaat cagtcttaaa aagcctctaa tatcaataag
     2581 atactagaag ccttttaatt atttaatcta atttattgaa attcctgcac ttgcatatcc
     2641 ttctacagta ttaactaatg aaagacctga agctgttgca gtaaatacta gtaagaatcg
     2701 agtttctgct gttgctgcta tatttaatcc tgttacaatt ccactagaaa ttgaaccaac
     2761 tgataatatt cctgtaagtg gtggagctag tgtaactgtc gctcctggta cagctgtaaa
     2821 tgagttattt ggtgcagtag attggtaaag tgttgctgta attgtaattg ttgaaccaac
     2881 aattgaaagt gctgctgttg tgctgaagta tgctgaaata gatgttattg ttccagctct
     2941 tggcattgaa aatgcaaagt tagtcaatgt tcctgctgcg tttgtaagat ctattactcc
     3001 accaactata cttacccctg gagctgaact accaaaacca acaaatcctg gtgtacctac
     3061 taatcctcca gctatagttg taagtgatag tggtatacct gatgcaaaag gtattattgc
     3121 actagcacct gttggacctg ttgggcctgt tactccagtt gctcctgtta ttcctgttgc
     3181 tcctgttgcc cctgttggac ctactaatcc atctgctcct gttgcccctg ttgctcctgt
     3241 tgggcctgtt gccccatctg ctcctgttgc ccctgttgct cctgttgggc ctgttgcccc
     3301 agttactcct gctactccgg ttgcccctgt tggacctgtt gggcctgttg ctccatctgc
     3361 tccggtattt cctgttgctc ctgttggacc tgttgctcca tctgctccag tatttcctgt
     3421 tgctcctgtt gctcctgttg gacctgctac tccatctgct ccggtatttc ctgttgctcc
     3481 ggttggacct actaatccat ctgctccggt tgggccagtt gctccagttg cccctgttgc
     3541 tcctgttact cctactccgg ttgctccggt tgcccctgtt gggcctgtta ctccatctgc
     3601 tccagttgct ccggttgccc ctgttggacc tactaatcca tctgctccgg ttgcccctgt
     3661 tgcacctgtt ggacctgtta ctccggttgc tccatctgct ccggttgctc cggttggacc
     3721 tgttgggcct gttactccat ctgctccagt tgcccctgtt actcctgttg gacctattaa
     3781 ccctgttgct ccggttgggc ctgttggacc tattaaccct gttgctcctg ttactcctac
     3841 tcctgttgct ccggttgggc cggttggacc tgtcactcca aatcctgttg ctccagttgc
     3901 acctgttgga cctgttactc catctgctcc ggttgtccct gttgctcctg ttgggcccgt
     3961 tgcccctgtt gctccatctg ctccggttgc tccggttgga cctgttggac ctgttattcc
     4021 tattcctgtt gctcctactg cccctgttgg acctgttact ccaggtgttc ctgttgctcc
     4081 ggttgggcct attaatcctg ttgctcctgt tactcctact cctgttgctc cggttgggcc
     4141 tgttggacct gtcactccaa atcctgttgc tccggttgca cctgttggac ctgttattcc
     4201 atttgctccg gttgctccgg ttgggcctgt tgggcctgtt actccatctg ctccggttgc
     4261 acctgttgct ccagttgcgc ctgttggacc tgttattcca aatcctattg ggcctgttgg
     4321 acctgttgga cccgtcggac ctgttggacc tgttgggcct cctcttccag ttcctcctgt
     4381 atttcctgtt ggacctgttg ggcctgttgg acctgttgga cccgttgcac ctactcctgg
     4441 tcctgttgga cccgttgggc ctgttgggcc tgttctacct cttggaccca ttggacctgt
     4501 tggacctaca catgatggcg gacagcaatg atgacaatca cagctattat aatcatcacg
     4561 accactgtta caatcatcgt atttatcata gccattgttg taatcattat catcaaatgg
     4621 tccaaaatat ttatttctac tcattattaa aagcacctcc tgatatattt gagcttctaa
     4681 gctctatata taatatgtca aatttagtat tattgtgacc tatcaactat ttttaaattt
     4741 attaaaataa ttttcattgt gcaaaacagc actatcatta ggtttgattt cttttgtttt
     4801 ttcatgataa taaatagctt tatttgattc tcctagcctg tcataacaga cacttaattg
     4861 tatatatggt atatatccat aacaatcatt tgacttaaaa cctccattag tatcattctt
     4921 atctcttgtt agtgctacct tataccaaaa aatagcttct ttatattttt gtctatcaaa
     4981 catatgcttt cctatgtcac aacaaatttc tgctcttggc tcatcaaatt caaaacttct
     5041 aaacaaagaa tataaggcac tcttttcatc attaattaag taataacatg tggctaaatc
     5101 tctgcaagca ctgatacaat cctcaatcca tcctcttgat gagtctaaaa acttagtaaa
     5161 accttctatt gcttctttat acttagcatt atagtacaac tctctagagt aataaaattg
     5221 gtgtcttggc tccaatactt ttccttctga aatcattttt tcaaaaattc taagatttct
     5281 tagagggtct tgtctatgaa gctttttatg agatattgca atgtcagaat aaaatacctc
     5341 tccagaaaga ggtactactt catgaatagg gtcaacccat ttatgattag aacttctttt
     5401 aaacaatcgt tctctataat acgagagagt tgggctacca ttttcatcaa aggatacatt
     5461 gtattttgcc ataacaatat caatggaagt atccaagctt tctttaatct ttaataattt
     5521 ttctctatca gcttctaaaa ttatgtcatc tgcatcaagc cacatcgtat agtctttaga
     5581 agctttagaa aatgaaaaat ttcttgcagc agagaaatca tctatccatt cgaaatcgta
     5641 caccatgtct gtatattttg agactatttc ttttgtggaa tctgtagaac cagtatctac
     5701 aattataatt tcgtctacta tatcctttac acattctaag catctgccta taacttcttc
     5761 ctcattttta acaatcatgc acaaacttat tgtaatcata atgtacaact cctttgtctt
     5821 ctatatattg cagacataag taatatatgg tattttctct tgttttgtta ttaaatttat
     5881 aaaaactttt gacgacagaa agttactaaa aaaccttatc ttttatgtat ttttatggta
     5941 gaatttatta aacttgaaat ttgatactag ttattgaaat aataaaacta tatttaattt
     6001 catacaaaaa agagcatccc ataaactaaa aagttcactt tgagacactc ttatttaata
     6061 ttctatatat atttataaaa cagatatttt aatatgatac tttattcatt cctattcatt
     6121 atataatcaa tcagtccata ctctttagct tctagtgcag tcataaaatt atctctatct
     6181 gtatctcttc taatatcttc tattgattta cctgtatttt cagaaaaaat tctatctaat
     6241 cgttctttta ttttcaatat attatctaca gctattttta catctgttgc ttgaccttta
     6301 gctcctccca ttggctggtg aatcataatc tctgcattag gtaaagcata tctttttcca
     6361 tgtgttcctc ctgcaagtaa aaaagcactc atacttgcag ccataccaat acaaatagtc
     6421 gatacatcac atctgacata attcatagta tcatatatag caaaccctgc tgtaacagag
     6481 ccaccagggc tatttatata tataattata tctgaatctg ggtcttctga ttctaaaaac
     6541 agtaattgag ctactactaa acttgcaata gcatcattaa tttcttctcc tataaatata
     6601 attctatctt ttaataattt tgaatatata tcataagacc tttccccttg acttgtttgt
     6661 tcaattacat gtggtactaa actcatgcta ctttcacctc acaattaata ttaaagttaa
     6721 gataagaatt aatttcatct attctttgtt tacaattcat atttgcataa gaaatatatt
     6781 tttcgctttg aatctgatga tttagattta aaacaaatct ctgttgaata ggataaaatt
     6841 catctttatt tctatatact tgtggagatt ctttatataa atttctaaat gctagtgtaa
     6901 aagattgatg tgtagaatat cctgctgtaa tagctatgtc tataatatat ttgtctgtaa
     6961 atataagctg tctagctgct tcagtgagtc tcctcctctg gatgtattga tgaatagtac
     7021 atcctacaat gtttgtaaac attctgtgta aatggtattt tgaataatta gcaatatcag
     7081 ctattttatc taaatttaga ttttctgtaa gattttcttc tatataatca attatctcca
     7141 taataacatc tgtatttgtt ttcaactcta tcctctcctt ttaagtatta taacctatgc
     7201 aaaaagtttt ttcttaatat aaattgctat cttaatttag tgtatagcaa caaagtatcg
     7261 ataacacaat atcaggtatt tttatacaaa aatattaata tatatttctt ttaaagttta
     7321 aacttcattg catctattat atgtagattg ctatatgttt tatctatgta ccttgattta
     7381 tatgtattat tttgctgagt atttttacac ctttttcaat ttcatcaaaa ctaagatgag
     7441 cataacctag tataatttca tggtcatatt ctaatatttt ctcaattgca tattgttgta
     7501 taggataaac ttttatgcct gcttcaaaaa ttttatgaat taaactttcc gtaaatttaa
     7561 cattatagaa atgagcaact atatgaagcc ctgctgcttc accttttatt ttaaattcat
     7621 ttttaaattc cgtgtttaaa acttttatga ggtacttacg ttttctatta tacaacttct
     7681 tcattctaaa tatgtacttc tctaaacctc catttccaat aaattcagct aatacatgtt
     7741 gtaatattgt ttctgtatga acatcagagt acatttttaa ggttttatag ctttctaaaa
     7801 tattgtctgg taataatata aatccaacac gaatggctgg agataatatt ttactaaaag
     7861 aacctatgta aattacttta tttgggttaa gttcataaag agaactaatt ggttgaccct
     7921 catatctaaa ttcactatca taatcatctt caattatata gtaaccattc tccgttgcat
     7981 atttaataag ctccagtctt ctttgaatag gtaaaatccc tcctaatggg tattgatgag
     8041 aaggtgtagt ataaacaaaa gaaatcccct ttattgattt tattaagttg gtatttattc
     8101 ccttatcatc tactttaact ccaacaactg aatatccaat agatgaaata acctttaata
     8161 agcctttatg aatagggtct tctacagcaa cctttttatt acttttgtat aaaagctgtg
     8221 aaattaaaga taaaccttgt gttgaaccag aaacaatcat aatgtttttg ggattacatc
     8281 taattcctct agtacgaaat aaatacttag atatttccgc tcttaaaacc catacaccag
     8341 ctgtacttcc atatctgaaa tccgaatcag ataaatcata cagtatttgt ttatatagct
     8401 ttgaaagttc tttgcgtgga aatagtttta attctggaac tcctgaacga aaatctatat
     8461 aatttttttg tttattagta tgtaaatctt tttcatctct aaaaatataa tttaacttaa
     8521 aatcaacttt atgccctgat attcctttag ctacaattgt tccatatcca ttccttgttt
     8581 ccaaatatcc ttctgcaatt aattgattat atgcatctaa aactgtatta cgagatacag
     8641 atagttcttt tgataaagtc ctagatgatg gcaatttttg ctcaaacttt aagcttccat
     8701 tcagaatcat atcttttatc tcacaataaa tttgtcttga taatgatata ttactatttc
     8761 tattaatcgt aatccacatt ctaatacctc caaaagtggt tctataaaat tactataaaa
     8821 atggaactac aaaatctact tttaacttgc taagattata tcataaaaca aaaaataaaa
     8881 aggagtctat attatgttag aaatatcaca taaagtgaaa gaaatttatc ccaatattaa
     8941 atttggagtt atggttataa atattacaca ttcaaaacct aataaagaaa attttttaat
     9001 tcttaaaaac tctacaatta aaaatattat agaaaaacat ccagaataca atcgtaaaga
     9061 aaaaattaaa acagagcctg tttcaagtta tataaagtat tacaaaaaat tcaagaaaac
     9121 ttaccctgta ttgcttcaat tagaatctat tctattaaaa tcaaaaggta tcccagatgt
     9181 aggtgtaaca attgagtcaa tgtttttagc agaattgaaa aatcttcttc taacagcagg
     9241 tcatgacctt gataaaatag aattaccttt gaaaatagac ttagcaaatg gaagtgaaca
     9301 tttttatggt ataggtgcta aagaacagat tttgacaaaa gatgatttat ttttatcgga
     9361 taatattggt atattatcta gcattcttaa tggacctgat aatcgaacag ctataacaaa
     9421 agatactaaa aatattatgt attttgtata tggacctgat aaaatatcag aaaaacaaat
     9481 tcaagaccat ttaaatgaca taaaatacta tatttcaagt gcttttccag atttaaaaat
     9541 taattcaatt gatatatttt agttaatata ttaaaatcct cacaaatatt ttgaacaaat
     9601 aaattagtga agtatatatt ctagttaaac tagatatact tcactaaaat taattatata
     9661 gatattattt atctaaggat attatttatt ttgagtttta tttataataa acactttgtt
     9721 acatttaacc tatgaataac ttaattttat aattaaagaa tttcataaga aacaatttca
     9781 cttaaaggaa cacgagtttt ttcatgtcta tctgggctat ctgctacctt agattcatat
     9841 cccatcaata aaatatttat tggttctaga ttatctggca aactaaactc ttctctaatt
     9901 atatctggat taaaatagca tacccaaaca cttgccaatc caagttcagt tgcttgtagc
     9961 atcatatggt ctgtaactat acttgtatca atatctgtaa gttgcttccc atcaaaaggt
    10021 cttgtccaaa ccttctcttt atctccacac acaagaattg ctaatggagc atcatatata
    10081 ttggcagcct tggaaagttt atttagaccc tctttttcct gaataacaat caatctttga
    10141 ggttgacgat taccaccagt tggagctatt cttgcaacat ctaaaacctt atcaagtttt
    10201 tctttttcaa cctttctatc ttgataatta cggcaagaat atcttttttt tgcaagttca
    10261 acgaaattca tttatttacc tcctattgtt ttattagact aagttgatga tttatttaac
    10321 ctatgctata attttagcac tatggtaata tattacaata atgcactttt ttgtaatata
    10381 gtacctaaaa agatacttta aaataaataa aggagtccaa aaatgaaaaa atgtttagat
    10441 aattacagtt gcccaataga agcaacactt gcattgattg gtggtaaata taagacactt
    10501 atactttggc atcttaaaga cactatattg aggttcaatg aattaaaaaa attaatccct
    10561 aaggcaacac ctaaaatgtt aactcaacaa ttacgtgaat tagaatcaga tggtttaatc
    10621 ataagagtgg tttatcctgt tgttcctcca aaagtagaat actcactatc tgattttgga
    10681 aagagtatta ttccaatttt agattccatg tgcgactggg gttctgatta cttggaaaag
    10741 ctctaaacta ttacagttta aatcccatag ctaatttaac ttcatccagt tgttttttag
    10801 atatcaacat ttctaaaagc ttaaaagcta catgtggagc tgtttctgta taatatgagg
    10861 ttataatgtt ttgatttaca acagttggtt cattaactac atttacatca aactcactta
    10921 actgtctttg tcttttacta tttttcaaat gatatgtagt agctttacga ttttttaaaa
    10981 cacaactttt tccaatcagc aatgctgaca cacaaataaa agcgattatt ttttctttta
    11041 aattaaactc ccttattaga tttaaatatg atgacattct aatgcagtat catattccaa
    11101 tatagttttc ttaaattctt ccatactttt agataaatcc gtattgataa atacaaaagc
    11161 caaaagctta tattttattt tttcctgatt aatttgaata gtgtactttt gaattaaatt
    11221 taattgctca attttcctta tatgctctga gactgctggt attgataaat taatttttct
    11281 gcttatttca gaagttgaaa cctaccattc tttcttagag aattaattat ttttaaatct
    11341 atctcatcca gacccactca ccgccttaat tatttaatat aatttaagct aacaatttac
    11401 attaagtaaa taattttaat tatttcaata aaacttaata caaatatatt attttttctt
    11461 agaattttag cttatttaat caaaatacat attacactta aaattattta agttgaatta
    11521 atgtttttat tttgtataat atattgctta tttttgcgac aataaaagat actccataat
    11581 ttatgaagta cttttactat atgtttaatc atttagttat tatatcagtt actttcatac
    11641 tattatattt ttatttctaa taattatata tgtacattag catatcattg aaaatttaat
    11701 aatattatcc atctacttct acatgttgca atatttaata aagatagtat acctgtatca
    11761 aaattataaa tctcgtaatc ttaatttttt aatagattat aaaattttat tggtggtgag
    11821 tcttcaaata actttgtaat gatagattta ctaaattaat aggttatgta gcaaatataa
    11881 ctttcttatt gactataact aagtattatg ataacatgat ttaagctata attaataaaa
    11941 tatattttaa gtaaataagg caatatacaa agtacaaaag tacaatttaa atatagataa
    12001 actagaatta atactaagat taggatgtga ataattatga tttatataga attagttaaa
    12061 cttgttagaa aacttaactc tacacaaatg tatacgatga agcgttgtgt agaggttaat
    12121 ctgaaagctt aaagctttct atcttcatcg gcaaatatag gtttagtgta gtttttgggc
    12181 tatgcttatt taaaattacc tatttgccga tagataatat agattttctg gtcatagaca
    12241 acaatgcttg tctatgacct tttgtttttc caaaagcaga ggtcggcatt ttataatgtc
    12301 attcctctgc tttttttatt tccataaatt ttttaataaa agaaaaggag tttgaattat
    12361 gagtttatta aaagtaacta atttatcaca atgttttatg gataaatcac tgtatgagaa
    12421 agctaacttt gatttattca aaggtgaaca tataggtgta gttggccaaa atggtacagg
    12481 caaaagtaca ttaattaaaa ttttattggg agaagttatt ccagattcag gagaaatcaa
    12541 gtggcaacct aatatcaata taggccattt agaccaatat gcagaaatca atagagatac
    12601 aacaatatca ctctatttac acactgcatt tgaagaactt tataaaatag aaaaggagat
    12661 gaatttactc tatcaagaaa gtgctatatc tggaaatgag caacatctaa tcaaagcatc
    12721 agattatcag gaacaattaa tagcaaataa tttctattct atagataatg aagtaaataa
    12781 aatagcaaat ggtcttggat tagattcaat aggaatgaat cgtgttgttg gggagcttag
    12841 cggtgggcaa agggcaaagg taattttagc aaaattgcta ctttctaacc atgaggtttt
    12901 attattagac gaaccaacaa actttttaga taaagaacac gttgaatggc tctcaaatta
    12961 tttaaataca tttagtggag catttattgt agtttctcac gattttgact ttttagagaa
    13021 aatttctaca ggtattcttg atatagaatt tggtatgatt aagaaatatc atggaaaata
    13081 ttcagagttc cttaaacaaa aattacattt aagagaggat tatattagaa gatatcaatc
    13141 acaacaaaag aaaatagaaa aagaagaggc atttatacgt aaaaacaaag ctggagtaaa
    13201 ttcaaaaatt gcaagaggaa gacaaaaaca attggataaa atagaaagaa tagctcctcc
    13261 tggttttaca ggaaaaccaa atataaaatt ttcagaaatt gaaatatctg ctcaaaatgc
    13321 tcttacagta acaaatcttg aagttggcta ctactattct ttgcttccaa aattaaattt
    13381 ctctgttgat gggggtcaaa aaatagttat aacgggtttt aatggaattg gtaaatctac
    13441 tttgttaaaa acattagtta aagatattcc ttgtatttct ggagatttcc agttttctga
    13501 acaagtgaaa cttgcttatt atgagcaaga tttaaaatgg gaaaatccta ctaaaacacc
    13561 gcttcaaata gtagcagata aatatccgaa attgaataca aaagagatta gacgtcatct
    13621 agccagatgt ggcgtaaagg aagaacatgt ttcaaggagt gtatctacat taagtggtgg
    13681 tgaacaatct aaggtaaaat tatgttgtat gatgttattc ccttgtaatt ttttgatttt
    13741 agatgagcca actaaccact ttgatgcaga aacaaaggat gctttacaaa atgctttgaa
    13801 acagtttaga ggaagtataa ttctagtttc ccatgaagaa aaattttata aaggctggat
    13861 tgacaaagta tttaatatag aaaaacaatt agtgtaggtt tatatacaat atgcgatatt
    13921 gtttaattag catttcaatg caaattttaa tctcctagtt aatgtttcac tgcaagtaaa
    13981 ctaaaaaata aatatttatt agagcataaa gtgcattacc acggtataaa tttaatgagg
    14041 ctatctcaaa atagagataa gcctcttctt cattattgat ataacaaaaa tacatttgat
    14101 ttcacacaaa aaagaatgtc tcattaacta acaaattgaa tttgagacac cttcattgat
    14161 actaagatct attctaatcg attctattca caagtttata tcctagacct ttaactgtta
    14221 taagtatttt aggatttgag gggttatctt caattttttc tcttatatgt cgtatatgca
    14281 ccataattgt attgtcacaa atactactgt atactcccca tacttgttca tagagtcttt
    14341 cttttcctat aattttattt acattttgag ccatgtagct taaaagatga tactcccttc
    14401 cagttaactc aatctctttt ctatctttat atacacggtt tccttctata tcaatagtaa
    14461 tatctcctat cttaataact gaactatctg atggtacaat actttgatac tgttgtctac
    14521 gtaattgcgc tttaactcga aaaacaattt ctcttggact gaatggcttt gttatatagt
    14581 catctccccc actactaaga cctagtattt tgtcaatatc atcatttttt gatgagagaa
    14641 aaagaataga acagtatgaa aactctcgaa tttttttaca cacttctatg ccatctatat
    14701 ctggtaacat tatatcaaga atgacaacat ctggacatgc tatcttacac agcgaaatag
    14761 catctaaacc attataagct ttaataatgt ttttaaaacc atcatttata agtacttctt
    14821 caattaaatc tactatatct ttttcatcat caacaagtaa tattttttta ttaaaatatg
    14881 tatccatatt gaaatctctc cataaaaatt tattatattc taatcttgca gtatcactat
    14941 cttgtttttt tatattcact actcttgctt ttacattact aatagtaaca tctctaatat
    15001 acaaattcaa tcactatgaa aattaagata cgtttcctta aaataaagta tatgatacat
    15061 taaaacctat agaaaattaa tttcatccaa agtttataat attagactaa tacacttaca
    15121 gatacagatt aatacaatag taaaataaaa ggagttgtct taaaatcgac tttttctaat
    15181 caaactttaa gttcaactcc ccttttaaac ttttatatgt tatttttatt aattctttat
    15241 atcaattata actttaattt tcaatagtat ctatctacca ctaattgaat tacttattaa
    15301 aacataaaat atctacctaa actatttatt taatatctac atatatttat atctattctt
    15361 atgcttacat atacaaaaaa cggttaaaaa taaagttaaa atttcagcac ttggtactgc
    15421 taaccatatc ccatttatat ttaacatatt tggcaatatc aataaaccta tagttataaa
    15481 tccaaatgta cgtagaaaag ataatattgc agacaccttg ccatttgaca atgctgtaaa
    15541 catagatgag gtaaaaatat tatatccaca aaaaataaaa ctaaaagaaa atatataaaa
    15601 tccagacctt gcaatttcat aaactcggct tcctctttga gaaaaaatct ctacaatgat
    15661 tggtgaacat gatatagaaa agataaatac caataaagat gccactgaaa taaataatat
    15721 acaaatctta aaaacatgat ttaactgtgt attattttca cttccataat tataacttat
    15781 tattggtgca acacccattg agaaacctat ataaagcgaa gttaaaagaa attgagaata
    15841 aataattatt gtaatagctg caactccatc ttcactaatt aatttcatca tcatagcatt
    15901 aaataaaaaa gtagtaactg ctgttgatag ttgacccacc atttcagatg aaccattaaa
    15961 acaagcttca aataatattc ttttatctag tctgggtata caaaatttaa gtaccccttt
    16021 attttttgaa aagaaaacca tacctgaaat ggtaggaatt aggtatccta ctccagttgc
    16081 aagtgctgct ccactaatac ccatttgtaa cagaacaata aacacatagt caagaattat
    16141 attagcacac cctgcaccta acactagcca taatccaaat tgaggctttc cagctgttac
    16201 aaataaacat tgaaataata cttgtagtat attcgcagaa gcaaaaatca agataataaa
    16261 aatatatgaa tgacaatatt taattaaaac ttcacttgct cctaaccata taatgatata
    16321 atccataaat acaataccta taccagtaat tattacccca attacaactc ctgataatac
    16381 gattaaagag aaagctttat ttgctccctc aatatcacca tttcccatct tacgtgctac
    16441 aatagcactt cctccagtgg caagcatagt tccaattcca actataagat taataattgg
    16501 acatacaata ttaattgctg atagagcatt tgtattaata aatcttgata caaatatagt
    16561 atcgacgatt gtatacaatc ccataaaaat catcataaaa atagtaggaa atgcaaactt
    16621 caatagagta aataaattaa atctttgtgc cagtaaatta tcttgctcat aaagattatc
    16681 ttgttcatga ttttctgaat aatatacatc actcattttg tttatttttc tgtacattaa
    16741 ttatttttaa aatatattcc aaacaattag acatttacag acctcctttc tgcataaaaa
    16801 ttatatctaa ttatttggat atagttttaa ttaatcttgc ttttttacac aattatattt
    16861 atactaaagt aacttttaaa tccttacttt aatcatttta tagctttcaa tgcctttagt
    16921 gtaaatactc gtttacatag tctagtgtca tgtgaaacgt atttatatat aattatattg
    16981 tctattttcg ccaatttatt aactacttgc acttttataa tgtctcagac ctaacttcca
    17041 aaatctccac ataaacaatg taaacgaaaa tacaattaaa attgaatata ttaatccatt
    17101 aatagttatt gttccagcca aaatttgagt tggaattgtg gacataattc catatggtaa
    17161 gattaaatag aataatactt taaaaacacc ttcatatatt acaccaggaa ttttcatatt
    17221 cattggcaat aaattatctt ctaatctcat tatcgcagaa gatgatataa caaaaaatga
    17281 aactgttcta agtataatac atacatcata aaaaagtaat gtcatcaata gcaccatgaa
    17341 aatatatatt attattatga ctaaagttat ctctgagttt aattcagaga ttccatataa
    17401 aacaataagt atacttgcta aaattaatgg tgatgaacca atattaatat tttcaaatgt
    17461 taacctaaat agtgggtcta ttggttttgt aatatagtag tctaattctc cttcctgaat
    17521 ttttcgtgga atatcataaa taccaaaaaa gaaaatcgtc atatttatcg catttattaa
    17581 tgagaaagtt cctataaata ttaacatctc tccttgttgc catcccccta ttgagtctac
    17641 atgagaatat atactattaa acattagaag ttgtaatata aataatgaac tatctacaaa
    17701 aaatgctcca aaaaaatcaa atctaaatac catcatcttt gataatttca tttttaataa
    17761 cataaatatt attttcaaat tttttttcat catataccca ccccatcaaa taatgttctc
    17821 attcttttat acataacttt atttactaca gaaaagaata aaacccataa tgctaaaata
    17881 attaatcctt gtattgcttc attgctgttt ctacctatta gtaacataga tggcaaatat
    17941 gttgtataat aaaatggaaa taccttcata acttttacta tagtttctgg taaaagcaca
    18001 agtggtatca ttgttcctgt aataaattca acaatatttt ctattatcat tctaaaaaaa
    18061 ctaatctcaa gaaatttaaa tgacaaaatc ccaataaaga agtggagttt catcataaaa
    18121 ataagtccta gaaaaatcat aaaaattgaa attaatattt gaattggatt tgatgtaaag
    18181 gcaaaattta ttttaaatat aaaaatccat acaaatgcag aaatcatatt aaatacaaaa
    18241 taaaaacatg tcattccaaa atttttagca ataaaataat tttgaacatt aattggaata
    18301 atcatgtact ttgaaaatgt gcctaatttt actcgattac atatctcttc actggtactc
    18361 ttcgacatat caatacctga taaaaatgag cttattatat agtaagacaa catagagtta
    18421 aatgtaaaac cagagactat tttattttcg ccaaaaattg ctttccataa aatataagca
    18481 aataaaattt ttacaatcgt aaacatcata ttaactacca catcaaatct ccagataagt
    18541 tgcactttaa agttaatttt ggctacttca taataccttc taatactctg tttaaattta
    18601 taaaacattg aagaatttga acttgcttca ttatagttgc tcataatact catcacttcc
    18661 tttcttatat attctctcta caatattaac tatatcttct tcttcaatca ttacatcttt
    18721 aacatcatat ctatcaaaaa tccatttaat cgtttcattt cctctttctt ttggcacaac
    18781 tactgaggtc ttatgatttg tttgttcaac aactttacaa tcttttgaaa atacaatgtt
    18841 agtttcattg gaaaaactaa ctgttatttt tttatatttt tgaaaatgat taaatagttc
    18901 ctctgtagag ccatcatata ttttacggct attttctaca acaatacttc tactacagag
    18961 actcttaata tcttccatat aatgagaagt aagaataata gtagttcctt ttgtttcatt
    19021 tacctctttt agaaaatacc taatttgttt ttgggctaca gcatctaaac ctatagttgg
    19081 ttcatccaaa aataatattt tgggattatg tagaagggct actattagtt ccattttcat
    19141 tctttctcct agggaaagtg tcctaacttg aacatttaaa tattcagata cctcaaataa
    19201 ttcgataaag taatccaaat tttttttata ttcttcatta gatatatcat ataattcttt
    19261 aaataaaaga aacgtatctg ctggtgtcaa ttcaaagaat agttgacttt tttgacccat
    19321 aacaatagca tattgttttt taaaattatt ttctaattta ttagggtaat aacccataac
    19381 agatatttct ccagaagatg gtgcaataat accagttaac atcttaataa gagtagtttt
    19441 tccagctcca ttttgaccta ttaatccaac aaattctcct tcttctatct ttaaatcaaa
    19501 tgatgatata gctgtttttt ctgtatattt cctattaaat aaagacttta cactccctat
    19561 aaatcctgcc tttttctcaa atcttctata agatttagtc agttcattaa gttcaattat
    19621 gctcatttta atcgcctcca tatttcataa tttatataaa aaaatccaca ggtatatatc
    19681 tgcctttttc tatgcttata tttaacagca caaaaacaga aaactcctgt ggactagaaa
    19741 agttaatgct ctctatttca acatagttat caaaataata ctatacaaaa ttaataaaag
    19801 tgtagcagat taaaacctac tacaccataa tttaacaaag taatatatat tttaaatact
    19861 atttgttgtc atatgtcagt tatctataaa ggcagaataa gacacacaaa ttaaatgtat
    19921 taaaaataca cttaaaattt ctgattatac agaatatatg tgtctccaac tatttaattg
    19981 ttggttacca ttatacaact ccgacatcaa ggcactcctc tcataatatt attatcaaca
    20041 tcatatcata aaggttattt atgttcaagt atagattcat atactaatat atttagttta
    20101 tttcctcagg gttgaattta aatttcattt ataatattca tttataaatt aagaatataa
    20161 tatgcatatt aaaacttgtt atttttcttt aatcttttta tcataaaaga tatacttttt
    20221 acctatacag gatgtaattt cttcagttct atattataat aagattgtaa taagggttca
    20281 acttataata cattaatata taaactgtaa atcttaaggg ggtaatctat gaaaaataat
    20341 acaacacaaa aaagattaag agatttatca aaaaaaattt ggaatattta tattttaaat
    20401 ccagaagaag aaggcattaa atttattatt tctttgttag atgacaacct tacattaatt
    20461 ggaacaggaa aacatgaatt ttacgaaaca ttagaagaat ttattatagg tcttgaaaaa
    20521 gaccaagtag aatcaaatca aatagacttt gaaattatag atgagtggta ttcatgtacc
    20581 aaagtcacag atgaaacttt tatagtatat ggtactcttt gggtaataga aaaagattac
    20641 ctagaaaaag atatctatgt agaaatggat actcgcttta ctatggtata cagagttaaa
    20701 gatgatataa ttaaacttat ccatgttcac cattctattc caaactttga ccaaatgaaa
    20761 gatgagtatt accctaaaac aataactgaa aaagcacaag aagcactagc aatggcaaat
    20821 gaatttaaac taaaatcaga aaaagacctt atgactggac tatacaacag acattttttt
    20881 gaagtacaca taaaagaaat gcttaaaacc gtttcacacg gatactttta tatctttgat
    20941 ttagataatt ttaaacaggt aaatgatatc tttggtcata ttcgaggaga tgaaatacta
    21001 atacactttt caaatatttt gactaaagtc ttcataagtg atgctattat tggaagactt
    21061 ggtggagatg aatttgctgt ttttgaatat agtaatcaat caaaagagga tgttgaaaat
    21121 aaagcaaaaa aagttttaga attgtgctta gagaataatt cttgttctat aggtatatct
    21181 agattagaaa ataactctga tactttccaa tctttataca aacaatcgga ttatgcttta
    21241 tattattcaa aacgaaataa taaaggaaac tttagttggt tttagtgcaa aagatattaa
    21301 aataggcaaa tttctcagag tatcttgttt tacgtactaa taggtaaggt aaacaacaac
    21361 ctatctttgc atatatttat ataaaccaac tattattaat agagctacaa tagtcatcat
    21421 acccactatt atagaatatt ataaactaaa aatattatta acatgattaa tattatattt
    21481 taataatttt atttttaaaa ataacaccaa aatattatat tttttgatta aaactgatgc
    21541 tgatataaaa aattctacta aaaaaatact taaaaaggct ctataaatag ccttttttac
    21601 ttttattgat taaatttaat ataaaattcc ttattaaatt tcaaattaat aaaaaaaaga
    21661 ttccacaaga agccttccat atttttattg attaaatcct aatatagaca atgccttagc
    21721 atcatagtaa gtagtcatct ctctcgtcgc atcctttaac ttaaggtaat caaaatctaa
    21781 tgttccacca aaaatagaag tgtattgaaa ttgtaccttt atgttttcat aatataataa
    21841 acttatttat taaaacatat tgtttaaagc agtacattta tatgtttttt ttgttcatct
    21901 gttttatcaa atatattagt ctttgaattt tgtttgtatt cttcagcatc tttatctaac
    21961 ttttctattc tcgactcaag tttcattatt tcttcttgtg ttaaatttgt aaaattttta
    22021 agcatatttt caagctcttc acgagtttta cctgctaagg ataagtcctc agatatcttc
    22081 tcttttttat tagaatcctc tttataatcc tttttttgtt ctaactcttc taatttttca
    22141 tcatttaaca tttcttcttc aactttttca ttaaactctt tagtgattaa agattctttt
    22201 tcatcacttg tatttagata agttgaattt tcatataaca ttgtactttt atttttatct
    22261 tctataatgc tatttttaat acctatttct atattagaaa agttattagt tgtttctctt
    22321 atttctgatt tatataagtt cttaattgct tcgtttattt ttttagtata aacctcttgt
    22381 ctatctttta aatctctaat tctatcatta agttcttgct tttgtttcat aatattagat
    22441 aaataagtgt cttttcctac agtttcattt ttcttaacta tactttcatt tattcttgta
    22501 ttatttatat tactttcatg tctaaatgaa tattgacttc tatattgact agatattttc
    22561 atttatttca cctctctaaa acaaatttat gttttataaa aagccaactt aacttaatta
    22621 tattttatca tcaaaagtat acatttacaa atattagtta atagttctat aggttcgagc
    22681 attattttca acaaaaaatt tttattataa attaaaacaa taatttttat aaatatctta
    22741 tttatatttt ataatttata tatttttact ttagaaatta tcaatattac agttttgctt
    22801 ttaagaaaca tctctatcat acataagcat atactctatt atgtattagt ataaatatgc
    22861 ctcttcttat ctcacataag aactctttat aaaagaacct atcataacaa acatgtatac
    22921 attatcatat gtatatatca ttatataaaa agtcaaactt tattaaaaaa attaataaat
    22981 tgccttaaat aataccataa atcaaatttg ccatcaaaat cacattaaag taataaattg
    23041 atggcaaatc taatatatta ataatatata gagtcataga acgaacagaa caaaaaaact
    23101 acactcatct tctaatcgtc ttatttattt ttgagatatt tttaaatttc ttttcttttt
    23161 ttgctaagta ttcgctttta ttgtctgcaa atactgcctc agttttaagc ctacgatagg
    23221 attcccatct tttaggcgaa agttcttgat gagcaatagc ttcccaaata gcacagcctg
    23281 gttctgaagt atgagaacaa ttacgaaaat gacattttcc gaaataagct tctatatctg
    23341 caaaactttt atctacacct tccgaaacat cccacattcc caactctctc atacctggtg
    23401 tgtcaataac aataccacca cctgaaatta aaaataactc tcgtctagtt gtggcatgtc
    23461 ttcctttatc atcagctatg cgaatttcct ttgtatttaa aaattctcca cccagcagac
    23521 aattaattaa tgaagatttt ccaactcctg aagaaccaag cagagcaata gtataacctg
    23581 gtttgatata cttagaaatt tgttgacaac catctgactc tttagctgat gtaacaacta
    23641 catctacacc caaggctata gaattaacta cttgtaattt acgatgtaca ttgtcacata
    23701 agtccgattt ggtaagtact actaccggga cagctccact ttcccatgtt aaagacaaat
    23761 atctctctaa tcgatgagtg ttaaaatctt tattcagtga catacacaaa aaaacaatgt
    23821 caatgttagc tgcaactacc tgttcctcat ttgcctttcc agcagcctta cgcacaaaca
    23881 agctttttct atgaagcaca tgatgaataa tagcattacc atttttatca ttacaacggt
    23941 caagtataac aaaatcacca actgttggaa aatcagatgg tatagtagct tcaaaacgta
    24001 gttttcctga aacctctgca aaaactatac cacctgtaca tacagcttga taaaggttct
    24061 tttcctgtga tataatgcga gcaatgtaca aatcatgata tttcatactc tgagtaataa
    24121 aattactatt tagaccataa tcttgtaaat caatctcttt cataccattc attctgtttc
    24181 ctccttctcc atcttttcag tgattctctc tagtgggaaa ggtggttgtg ccagtggttt
    24241 taatgcaatt gacattaatt tcactggatt atcatcagct gcaatacggt tagaactaag
    24301 atgtccacat cgtgtacaac gatgaataat tgcccattcg ccattttttc tcacccacac
    24361 tccaataggt tccatattag catcacaatc tgcagcacgg tcaccaggaa tgatatccac
    24421 atgaagacta tgtaagcaat gtggacaatg attcctatgt tgtgtaccag ctccttcagg
    24481 tactacaatg caaccacagt ttttgcaaat aaagttatcc aaacaggaat tttcctgata
    24541 ataagctcgt tttctatttt tataattcat ttttatcgcc tccatatctt gtgttttata
    24601 caaaaaaatc cacaggtatt tatatctgcc tttttgtgtg gtatatatat ttgcctacac
    24661 aaaaacagaa aactcctgtg gactagaaaa tttaatatct tctatttcaa cataactata
    24721 ttcaaaataa tactatgtaa aattaataaa agtgtagcag attaaagccc actacaccac
    24781 aatttaacaa agtaatatgt aatattatta tttgttgtcg aatgttagtt atctataaag
    24841 gcagagtaag acacaacaat taaatgtatc aaaaatacac ttaaaaattc tgattaaaca
    24901 gaacccatat gcgcctccaa ctatttattt gttggttacc attatataca actctgacac
    24961 caggcaagac actcctttac taataattat tattgaaatt ttatcataaa atatgagtat
    25021 gttcaagtat aatttaacat attcatatat ttatgtttat cttatttttt tattctatag
    25081 aatctagtaa tcttttgaaa ttcaatattc attcaatatt aatcataaaa attaaccgct
    25141 attatttctt ttatcatctt atatctctcc ctcaatttat ctaatttaag ttaataacaa
    25201 aggtctttta aacaaaacgt ataatcaagc tcttccatat attcttacat gaatagtata
    25261 tttttttata taaaataacg ttcatattta taaatttatt taattttcaa acaagtatat
    25321 tgaataataa tcaattctat tgtattattg taattgtaga ataaaactaa atcggcaaaa
    25381 ctagagaaat ttagtgacgc aaagctatag ggactaacgc ttataaaata aaatatgagt
    25441 tatgtcagcc agttgccaaa aagatatatt ctttttgttt ttatgaaagt tttttagggg
    25501 gataataata taatgtttag agataaaatg gatagatgta cacatatgtt gactgcttat
    25561 attggtagtt catatgatta ttgtgatttt atagatacac aactagatga ttttatacta
    25621 gagtacggag aaaatgtagt agaatcttgt ctgcatcaag tgatggtatt agtaagtaag
    25681 tacaattaaa tagagttggt tttctagaga acccttttta gttttatcta ctttaaatag
    25741 tcttatgtta gaaaactaat taaaatagat ttctagtatt catagtttta ttttttattt
    25801 aaaatacatg taataaagat gtaaatttgt atcaaaaaag aaatatgata acttaaattt
    25861 tcttatctat atgaaaataa atatctctta aaatgaaatt ctgtaaacat aaatgatttt
    25921 taagtttgaa ggattaaatt aacaaaatta taaatttgca aataagctat attaaaaaat
    25981 ataataattt tttatataac ttattctttt ataactttta attttaaaag aggagaatgt
    26041 atataagaat attcaatgta ctagaaaaaa tcaaaagaaa tattagaaga aatggatatt
    26101 gagtaatcaa agagaagatt ttgatactac aaatgatatg tttcaggaaa gcattcctat
    26161 cacaacaaaa attattcttg acgatatacc ttcacatgat gaattaaatc atgttttttc
    26221 aaaaggttgt gaatgaaaaa tgaaaaagag aaaaattgta ttaatcacat tactattaat
    26281 aggtgttttg ttattaggag gtatcctata taatcttttt ttagtaaaaa cagctaatat
    26341 ttcaatgcta aaggaatctt ggaatttgga tataccaata cctaacaaag aaattgaagt
    26401 atttgatact caagatagta ttaatggaga tggacaaagt tattttattc aagaattttc
    26461 tgaaaaaaat ttcaaaaaag tttttaattt aaaaggtggt atagttgtaa gcaaagataa
    26521 tattaatgaa atagaaaaat atattgataa atttaaaaga gactctgtta acattaataa
    26581 aagtaataaa aataaaattg aagaagattt taaaaaatat aagttagaag ttaaaaaaga
    26641 tgataagtat atatataaga gaaattatga aaactatgta gttttaatta taaaaaaaga
    26701 tgaacaaaaa ttatacagtt taatatggaa tcagtaggta catatgtatt attaagaatt
    26761 ataaataata aaaataaatt ttagtcaata tacaaaagcc ttttaaattg tctggaaatc
    26821 acctcttcat ttgttataaa aacatacaac aaatgaagag gtgattttat ggtttttaaa
    26881 aaaataatta taagtggata tgtgctttca catgtttatc aacatttgta atgcctatat
    26941 ttactaatga attataatat aaaaatatta aataatattc aactatagat tatgtaaatt
    27001 attctatgaa aaaaatgagt tgtataaaat ttggaaactg tagattgacg atttctttta
    27061 aaattacaat tataataagt tctatagagt taaaaataaa actttagaga tttttataac
    27121 attgtagact aaatttgcca ccaaaattac tttacagtgg caaatcggtg gcaaatacaa
    27181 tatattatta tcatataacc tatataaaca ttactattgc ttgattatct tagctacagt
    27241 ttcaacttgc tcatcatttt ccaaacttat attaagatct tcatcaatga taggtagctt
    27301 aaaagtaatg gattttagcc attgtccatt aggctgcttt tcttcataaa tttgaatttc
    27361 tgaaatgagt gcttctatta actgcctgcg ttcaacatcg ttcatgactt tataaagctt
    27421 gtcaaaataa atcaatactt tatatatgtt atcaccagta agtttctcaa cctctatcgt
    27481 ttcttttttt gctttagctt ctattaactg actttctaat tcctcaattt tatcgtacat
    27541 acgataaagc ctatcatcta aatcattttt tcttctctta taatgtttat cctctacatc
    27601 taaattatct atttcctcaa taagcttata ctttgtagaa tgactttttc ttagttcatt
    27661 ttggtaatta tctatctcat tttcaatagc agatgtatca accttcatgt taattttttc
    27721 ttgtatcata gatgcaaatt tagggttgct tactaacttg attattacct cagcaacggc
    27781 atcatctaac aattcttctc taatttgttt attataggta catttatgtc ctctattcat
    27841 aagtctatgc ttacaaccat agtaatagaa gtctttatac ttcgtcccat cttttttata
    27901 ttttatagat ttattcccaa acattccagc tccacatatc ggacacttta ctattcctga
    27961 taataagtgt gtcctcatgt tcttgccctt atttacatgt tcatactttt tagcttgtgc
    28021 tttcagttta acttgtgcag cctgccacaa ttcatctggg attattgctt catgaatgcc
    28081 ttctgctact aaataatcgt cctgctctac ttgtctgtat tcattccttg taccatgaac
    28141 tttttctaaa gttcttcttc caaatgctat tttcccgtta tacacaggat tctttaatat
    28201 ttttcttata agacctgcgt caaacaatgg atttttccca ttttgtcttg gtattttcct
    28261 tataccatga ttttctaaat atttagaaag accattagct ccaatacttg tatttacata
    28321 ttgatcaaaa atagttctta ttgcaattgc ttcttcctca tttattatca atttcccatc
    28381 aataagttga taaccatacg gagcaaatcc accattccat ttaccctctt ttgccttttg
    28441 aatccgacct tccattgttt ggacacgaat gttttctctt tctatttcag ccactgccga
    28501 taaaacagaa atcatcaatt tacccgcatc tttagatgaa tcaattccat cttcaacgca
    28561 aataagattt actccaaaat cctgcattat ttgtaaagtc gaaagtacat cagcagcatt
    28621 tcttgcaaat ctcgatagtt taaatacaag aacgaaagac actccatcct ttccggattt
    28681 tatatcttcc atcatacgag taaactgaac tctaccttct atagattttc cagacttacc
    28741 tgcatcttcg tattcaccaa caatctcata atcattatag agagcaaaag ccttcattct
    28801 tgatttttgt gcctctaaag aataaccatc tatctgtatg gatgtagata ctcttgtata
    28861 gagatatact tttatttttt cttttgacat agcattaacc tcaatatcct tattatatat
    28921 ttatatattt ttaccaataa aggtttggac tttaatctca agtatattat agcactttta
    28981 tttctctttc tcaatccgtg cttttagcta tatcaaattt attcttatcc tctgtatttt
    29041 ttactggagt aggatttgga agattctcta aatctaaaac tccagcatat tttgtaatca
    29101 gatttgctat caaatcagcc aatccattcc agtcattatc cactaataca cctcctccac
    29161 tttaaattct ttataaccaa atattatttt tcttactaag ttttatgaca ttggtaggtg
    29221 cattggctgc tacataggaa tctcacctcc gccccttgtt tcagacgagg cagcttaaac
    29281 tattgaagta tcattatcac cacttacatc atcgaaataa gctgccacgc ttatctttta
    29341 tgtattccta tctatcgctc attttcttct aacctcggca ttatgccggt attcatttga
    29401 accgattttc atcagcagaa aagtcttggc gtaggtcata actctcagta agtagataaa
    29461 gtcctacctt ggtctattca gttgtcaaag atcaatattt gaaagggact gttttcttta
    29521 cattttccta tttgccataa gcaggcgtat ctcctactca agaaagtaaa ggaggtcaaa
    29581 ctccccttca ctttacataa ggaaaatttg ccccctttgg ttaccaaagt tttaaagttc
    29641 ttcgataaat tttttcagct tttcaagaat tttgtttctt cttttgatta aagccggatg
    29701 tgtaatactt ttgagctttg ctactgaacg aacagtttca tcattgaaat acaagcgttc
    29761 aataatatct ctttcttctg cattgagcct tgttatagca cttcttactg cttcaatcat
    29821 catctgtgtt tcaacaatct tttctacatc aacactttca tcaacaatat tatctgtaaa
    29881 gtgtccgtca tgatccaatg ctgaaaaaaa gagcaagtgg tttttcctgt ccacctgctc
    29941 taaatacttc tcgtgttctt tttctcgcca gtagactata tatatatctt cactgacttt
    30001 taccttttgt cctctgatat aaagataata ctcttttgcc ataaagtttc ctccatctct
    30061 tttttatctg cttgtttttc agataaaaaa ggaggacttc tgcatcttgg cataagaagt
    30121 cctctgaaat gaaagaataa aaatatttct ttatatgaac ttgattgttt caattcgcac
    30181 ctgaaacaat catctactat acatattata aaaaagagga atgtattgaa ttctaaatat
    30241 ttctaacatt aaacgtttag atgcttccat atttatttcc tccattttat caataatcta
    30301 aataaccatc atattcatct actacttata taattgagtt ttattaaact ttttaagttt
    30361 ctattctatc aaatatttaa acagtctctg catccgaaaa gactaactca tatagtttta
    30421 ctaacaatat tttcattagc gtgttcaaat cctgatttct tgtatcaatt attttctgtt
    30481 cactttcaat aagaaaaaag cctttacttc catggctaat aataagtctc tatttttcaa
    30541 taactattgc aaaattatat cttgtttaag aaaatatttt aattttaaag ataaaaaatt
    30601 cttcatcctg caatgcttta tattctatat tgtaattatt cagaatatta cttacaatat
    30661 ataaacctaa tccattacta ttttccttat ttaaatcaaa tttaacatca aatattttat
    30721 ccatattcga aattttattg ttaccgtatg aattctctat atataaccaa tcattaacta
    30781 tcccaatatt aattacccca tttacatcag tatattttac cgcattacta atcaaattag
    30841 atagaataat ctttaaagct gtttttccta tataaacatt ctcatctaat atataattat
    30901 tgacagttat tttcttttga tttgctaata tttcatactt ttttaatatg tcttctaatg
    30961 tatcatttat tttcaaatat tcttcatcat tattcaaatt ttctatagaa tgaactgata
    31021 atatttgaga aatatttttt gttaaactat caacgatttc aatacattca ttaatataaa
    31081 tatctctttc tttatatttt ccaatattgt atttcatgtt ttccagtatt attttaagac
    31141 tagcaagagg agttttaagt tcatgggatg cacctttaaa aaagtcatat tttaactttt
    31201 ctaattttaa aatttcttta tttttaaatt ccaaatcgtc aattgttctt aataaagtag
    31261 aatacaaatc attaatttgt tgttttaatt ctccaacttc atcattagag ctaactttta
    31321 aacgcgtttt tttatcaagt ttcatcattt tatcagtaac aatttttatt tcttgtatat
    31381 tattttttat tgattttgca taaattaaag aaataatagc agaaaataaa attgatatta
    31441 ataaagaata tggtaaaaat ttaaggctta aatctttcgc atctttttgc atatcagctg
    31501 tagaaacaaa ttgtagattt gtttttttac catcattaag ctttatttct ctttcttcaa
    31561 ttatcaaaga attactatca ctttctaaat taacatttat attatctttg atttgtattt
    31621 cattcttatt atttttttct tttataaatg cttttatttc actactctta gaataaagct
    31681 ccaaagtttg ttctatatat tttatttctt ttccattcat attactagaa atttcatttg
    31741 ccatattatg aatcttttct tttctcgtct ccaaatatgt tttaggaaag ataaaaaaaa
    31801 ctaatgaatg aactaatata attattattc caagaacaga aaatatttgt atgaacattt
    31861 ttggaaatat ctttaatttt ttcattttct ctccaattta tatcctacat ttcttatagt
    31921 agttatacag tctaattgta atttttttct aagttctttt atatatacat ctattactcg
    31981 atcataagga gtttcttcgc tatctttcca tacataatca ataatttgca ttcttgttaa
    32041 cacttgtcca ttattatcca ataaacattt taatacttct agttcttttg catttacatc
    32101 tatttcttca ccatttattt tagctgtata gctattaaaa ttaaccgata gatcattata
    32161 ttcaaacttc tctaaatgtc cataattctt cttaattaaa gaatctattc tagcctttaa
    32221 gaccggcaat gaaaatggct tttctacata tccgtctact aaattagtaa atgcatcaat
    32281 tttatattct tcatcactaa atgcagtcaa gattagaatt ggtaaattgc ttttctttct
    32341 aatttctttc aacacttcta aaccatttat aaaaggtatc tgaatgtcta agataaccaa
    32401 atttatatcg ctattaaatt ttgacaaggc ttctcttcca tctttagctt gaataacagt
    32461 atatccaaat tctgaaagat attcacttat tccctctctt atcatattat catcttcaac
    32521 agttaatatt ttcatatata cctccactta agcctctaca cttatattat acagcatatt
    32581 atttgatatt taaaagccaa aaaatttttg gtgctaaaaa gcaccgaaaa ttttaattat
    32641 tgtcaattaa taattctttt ggattccttc ttaatatatt gaatgaagaa ataatcaatg
    32701 atacaagaag tactaaactc ataaatataa ctacataaat tatgaattta ggtaatacat
    32761 ttatatctaa acttgataat gtcttgttaa atccttcagc ttctgcccca ccacctaatt
    32821 ggctagatgc agattgtcta gctatttgtt tagctatatc accagtaacc ttattcaata
    32881 tattattccc aagcttatca gctgtatatt gagctaagaa ataagaacca acgaatgcgg
    32941 ggattgatat aaataccatc tcaattagga attgaccaaa aatttctaat tttgatatac
    33001 ctaatgatag taatactgct atttctttct ttctagcatt catccataag aataataata
    33061 atgaaactac aactcctgca aatattaatg agccaacaaa taatttattt gaaattgagt
    33121 agatacctga tatagattgt tgtaatgcag ggtaatttga tgaactttta atcaaattat
    33181 attctctcca atttatatct aatttcccaa gatcttttat tacactatca agattcttat
    33241 caccttttac aaagaatgtt gcatcttggt atacagctgt atcctctgta ttaccataaa
    33301 ctttagcagc tgtatgaaca tcagtgatta atgtattttc gtatagttct tgtgctgcac
    33361 ttactccacc gctattatgc ccatcgaata aacctttaat ttctacttct actgtttcat
    33421 ctgcaccttt ctcattatca gcatcaaata aattagattt tatttttatc ttatctccaa
    33481 ctttaagatt atttttttca gctaaatctt tatgcattaa gattttattt ttatcttcat
    33541 tttctaaatg ctttccttct actaatttat atgcttctga tacaaatttt gtttcttttg
    33601 atgagtcgtt aaccccagtt aacataactg ttcttttaaa attcttcgct ctttcaggtg
    33661 attgattcgc aagagtctct tgagtttcaa taatattata atcaactaaa tctgcaacac
    33721 tgtttattct ttttacatag gagtctatac tatctgtttg agatatcttt ttaatatctt
    33781 caccttttac atttccccca cctctaggtg ttcctggatt tacttgtcta tttatctcca
    33841 tagaaaaact atttgttata ttagcaaatg tttcttttga agctctgtcc gtagcatctt
    33901 taatagataa actaatgaga cttaaagttg acatagataa aataactaat ataataatta
    33961 atgattttaa gctttttcta gttacataag caaatgcatt ttttatcatt attcaacctc
    34021 caaattcatt ttatttactt ttttcaactt tttaccactt agttctaaaa tgatatccgc
    34081 agaatctgct acttccttac tatgtgttac aactattaca catttatttc tatctttagc
    34141 taatgtcttt aatatattaa ttatttctcc agcagtaaca ctgtctagat taccagtagg
    34201 ctcatcagct agtattattg gagcatctga taccaatgct ctagcaatag ctactctttg
    34261 ttgctgtcca ccagataatt tcataacatt tctttttatt tgttttttat ctaaacctag
    34321 ttcaaacaag atactttcat ctgctgattt atttactaat ctaatatttt caattggtga
    34381 taaataatct attaaattat agttttgaaa tactaaagat atattatttt ttctatgatt
    34441 actatatcct ttcttttgta tatcttcatt cttaaacaat atttttcctg tttgaggttt
    34501 atcaagtcca gcaagtaagg aaagaagtgt agattttcct gttcctgact ttcctactat
    34561 cgcataaaac ttcccaagtt caaatttttg atttactcct gacaaaactt tttctttaga
    34621 atttgcataa ctatatgcta cattctttat ttctaatata tccattattt tctcctaact
    34681 tatttttgat aatatttctt taggcttctt gattaatatt aatgaagaag caaatacaac
    34741 tgataaaaca ataatactta ttaatattaa ataactttgt ccaagtgttg ttatatttaa
    34801 cataaaacta ctattattta ttaaacttcc accggaaatc attgagttct ctgagttaat
    34861 gaatccatct acaattactt ttagtaatac atttcctaaa aataaggaag atattatact
    34921 tggtatcgat atgaatatta actcgaatat aaattgcatt ataatttgta tcttagatgt
    34981 tccaatagat aaaaatatac ctatttcata aattctttct cttaaccata gaatcaagat
    35041 taatgaaaga acaaccatcc cacctaacat aatagaataa gtcattattt ttattatatg
    35101 ttttattcca ctcactgact ctaaagactc ttcaaacgca ttagaatctt tttcaacaaa
    35161 atactttgac tcatcaattt taaactcttt caatttgttt aaggctaagt ctgtagattc
    35221 tgcactacca gaatacatta aaattttatt tgcgatttta ttattttctg atttatttaa
    35281 tatctcttgg cttgttgaat aatctacaaa caccatattt tcactaaaat cagaagataa
    35341 tcctgtatat gtttcctgtt ttttaccaga aaagatccct ataattttaa atttatgact
    35401 ttttattttt ccactttttt caatatctag taattcaaga tcaacttcat cacctaattt
    35461 tagattgttt tgtttagcaa attcttcatg aacaataatt gaattcttat cattttctcc
    35521 tatattttta ccttctttaa ttgtaaatac tccactacta aataaaatat ttcttttagt
    35581 attatttgta gcttcgagtg aaacaacatt cttaaattcg tcagataaat cttctctatt
    35641 tattctttgt tctccgctaa ctactttagc atcttttagt tttgctaatc catcatattg
    35701 aattattttt tcttcaattt cttttaattt ttcaatatct ttaaattgat taacattaaa
    35761 atatttacca tctttttttg ttattgatat tgaagaatta gaactttcat ataaagcctt
    35821 ttctatttca ttgcttgatt tcattattgt taaacaagaa tacaagcaag aaagaactat
    35881 agttaatatg ataaaaatta ttaaagttct atttctcttt cttgtaatat atgctatagc
    35941 attttttatc actttcctaa ctactcctct ctattttctt actccataac taattgcatc
    36001 cactggacaa gcatttttac atcgtccaca tctgatacac tccagatgat tgcaattctc
    36061 aactggatct atattcattt ggcaaacttt tttacatttt ccacaattaa tacacttatc
    36121 cttatccaat ctatatctaa atattgaaat agggttaaaa attgagtaaa tagctccaag
    36181 tggacatata tatttacaaa aaggtctata tataattata gaaagtaaca aagtaactat
    36241 tagaatgatt cctttccaat aatacaagaa acctatcgca tttctcatac ttttatttaa
    36301 taaaacaagt ggtaatcctc cttccagcat accaatcgga caaataagtt tacaaaaata
    36361 cggagaaccc tgacctaaaa tatcaaccaa aaataaaggt aatattatta caaatacaag
    36421 taatattatg tatttcaatt ttctcaaatg tttatcaaac ttaaatgttt caactttttt
    36481 aaaaaaggga atcttatgta gcaaatcttg aatcaatcca aatggacaca gccatccaca
    36541 aacaaatctt cccaccaatg ctcctataaa aaacaaaatc ccaactatat aataactaat
    36601 cttatatttt gaatttccaa ttactgcctg tagtgatcct attggacaag aaccttttgc
    36661 tcccgggcat gaataacaat tcatacctgg aacacaaatt ttctttaaat tcccaccgta
    36721 gattttacca gtcttaaacc cttcaaagta agaattagta attaaaaacc aaacggattg
    36781 aaataaatgc ctaaaacgat ctcttatttt atatttatct ttttttgtac taccatttat
    36841 aatattttta attctatcca attccaatac actccataca aattcttatc gccttatcca
    36901 agacaacttt agtttctcca ttactatgac catagtaaat catcgccata ctaataaaga
    36961 taattaataa agacaaggca cggcttttta aaaatttatt aaccatatac caatcaccgc
    37021 tttactttta tttatttttt attttttcca attctttttc aattacctgc ttccattcct
    37081 ttgcactctt tgccccagaa taagtatcac ctacaatatt tccattacta tcaacaaaga
    37141 aagtctctgg catagcctgt ataccattca atctaccatt aaagtttgtc ttatctggca
    37201 ttaagaaagg atatgaagcc tttgtctttt catgtattaa ctttgacttt tcaattgctt
    37261 ccttgttttc accgttatca tcaacagtat ctgtaacaac tccaacgata tttacaccct
    37321 tgcttttcat ttcattctga acctcaacca aatcaggaat ttcctttaca caagctgtac
    37381 accaagttgc aaatacattt accatagtaa gatcatactt ctcaaaatct ttacttgtaa
    37441 aatccttgcc atttatgtcc tttgttgata gtttacgtaa atctttaacc gattctttgt
    37501 taaatgcttc tgtattttct aaatcagttt tttctgatag cacaaaacca tttttaggac
    37561 gttctttttt atctataatt tgaatctcag ttctttttaa ttcatccaga agattacttt
    37621 cagctccgct atttatgctt aaatagcaat cgtattttcc atcacttgaa actcctattt
    37681 tagtatgagt atcacatttt gtaattttag atattttttc ttctgatgta tttttttcga
    37741 atataccaat agtcccaatt ctttcaagct cattttgcca atttttatat ccatcgccca
    37801 tcttttctat aactgcattc ttttgttctt ctgtcatttt ttcaaatgtc aaaatagcat
    37861 actttagttc tttatctata ggactttgat catctaacat cgctatcttt ttatcagcta
    37921 tataatttct aaatttgtct gagagtttaa atttaagccc taaatattca taaacatatt
    37981 ctttctttgc ctccaatgta taatctgatg gcttaaaagt ttcatttttg ccatttgcat
    38041 taattgacat gcctgcctct tcagaactta tggattgtcc ttctttaatt ttattgtttt
    38101 cattactttt ttgacaccca actgcgttta agctcaaaca taatgcaagt aataggcatg
    38161 ctcctcttga tactattttt ttcataaatt attcctcctt tattttttac acaatagcat
    38221 tttatagcta ctttcaataa cattctacac accttttatg aaacgttgat gaaatataat
    38281 tttttatttt tccaaactat ggtataataa tataagtatt atgcttaaag ttgttcttac
    38341 acgattagta tatgatcgat tagtatatga gcaagcacag taagtgtacg gacacttacg
    38401 gaaaaattga cgaagcagcc ctttgggatc tgcttctttt tttatcaatt tttagcttgt
    38461 tagggagaac cctaagaccc cgaaatacac ctaaaggagg aaatacctat ggcaaataga
    38521 atacgaaacg aaagacttga aattaaacta actgaagaag aaaaggctct ttttgaagag
    38581 aaaagaaaac tttcaaagtg tagaaatatg agccatttta ttcgcaaatg cgttttggaa
    38641 aaggagattt atcaggtaga tttagagcct ttccgggatt tacaagtctt actttccaat
    38701 gctacaaata atatcaatca gattgcaaag agagtaaatc agacaggtat catctataaa
    38761 gatgacatcc atgatatgaa aaaagcaatt gaacattttt caaaagagct gtggcaaatt
    38821 cattcactac ttctgaaaag aacatctgaa acggaaggtg aataataatg gctattacaa
    38881 aaatacaccc aataaaatcg actcttaatc ttgctatcga ctacattgta aatggagata
    38941 aaacagatga gcagctatta gtaagtactc ataaatgcca tgaatcaact gctcatactc
    39001 agtttttaag gacaagaaaa aacgtaggaa caaaaggaac cgttcttgca agacatctca
    39061 ttcaatcctt tttaccggga gaaactacgc ctgaaattgc acaccaaata ggtatggagc
    39121 tgtgtaaaaa gatactcaaa gatgagtatg aatttgtctt atctacccac atagataagg
    39181 ggcatatcca caatcacatc atcttcaata atgtaaatat ggtaacaggc aggtgctacc
    39241 agtctaacaa gaaaagctac caccaaatcc gttatcagag cgataattta tgcaaagaaa
    39301 ataacctatc cgttattgac gagttttacg aaatctataa gaaaaaatac aagactaacg
    39361 gtaaatcttg gtatgaaaat aaacaagcaa agcatggcac ttcttggaaa agcaggcttc
    39421 aatttgacat tgacagaatt ataaaacagt ctaaggattg ggatgaattt ctaaagaaga
    39481 tggcggatct cggctatgaa atcaaatacg gtaagcacat tgcttttaag tcaaaatata
    39541 aggcgagatt tacaagggct aaaacaatcg gggaagatta caccgaagaa agattaaaag
    39601 aacgcattgc agaaagagag tttataaaga ctcctgccgt caaaaaacgc atcggcaatg
    39661 ttattgacac gaacacaaat gttaaagtaa aagaaagcaa aggctacgaa tattgggcaa
    39721 ccaaacataa ccttaataca atggctgagt ctgttatctt tctcagagaa caaggtatta
    39781 aatccgttaa gcaacttgat gagtacatcc aaaaagcagc cgatgaaagg caaaatttac
    39841 aggataaaat caaggttatt gataaggaaa tgcaggagct ttctgctatt atggagcaag
    39901 ttcacactgt taaaaaatac aggcaatact acaaagaata taaggctaat ccgtctgaca
    39961 agacattttt tgaagagtac aaagttcaga ttaccctata tgaaaatgcc ctttcagagc
    40021 ttaaaaaatc ctattccaag ctcccaaatt caagggatat tttgtctgag cttgataaat
    40081 tacaagaaaa aaagaatacc ctaatgcaag agtattcttc ctcaaaatct attatgaacg
    40141 aactttacaa gatacgaaaa aattacggaa tttatatggg taaggagatg gagagatagc
    40201 tccatctcct tgcaaactat ttacagcaaa taatcatcta tctttgtttt attttgtctc
    40261 ctcgaaagca tgattctagg ataatcttta tttttacgta gtttaacata gccaaatttt
    40321 attaatgcct gtcccacttt atccttataa gaattatcca acaaaggctg tttattctcc
    40381 caaacattag ataactctga aatttctttt acagaggata tatagccttt cagaacatta
    40441 acactcaatc catttttaat cttagttaaa accaaagata ctttggtact taatttgata
    40501 tctggtgagc ttagtacata ttgcataaaa acttcattga gattttcatc ttccaaatcc
    40561 tccaatttgt cttcatcatc taatgacttt ataaactcat cttttaactc aaacatctta
    40621 aaggatttac atatatagtt aatatttacc gaagataaat ctccctttat aatatattct
    40681 atgataggtt ttttagttgg atttatcttt tcaactaaga cactatcttt tattgaatct
    40741 attagcttca tagaatttcc atctgcaata tcactattaa ctaaaccata tatcaactca
    40801 tcagaaagct catattttaa aagcatattt ataacaagtc cctctgccac atcgtcatca
    40861 taatttgcca gcgaaatcaa ttcggcataa tatgagttat tccataatgt ctcaatattc
    40921 ttttctgtca cttcaattaa tctctggtga actaaagtat taactctatt ttgtgttagt
    40981 ttatgattga cattacttat tggttcatcc gcatatttta tgacgaatgc aaaaatctta
    41041 tcacttacaa atgaactatt tataaaggta ttacaaacag aaatattatt ttttaatata
    41101 tcttcattat tatcttcatc caagttgtca ttgagatatt caacgaaatc atcactatat
    41161 tcttcaatca tattccaata tgaagctata ttatccgagc agaacttaac cttatttttt
    41221 cgtaataaac aatcaagtat tctagtcgtt acagagttat cttgtagatc agttaacttt
    41281 gaaattgctg tttcattctt ctctacatac tctaatttat attcatcaga aatatcagaa
    41341 ttaagaattc ttaatagtat ctcctcactg ttagtatagt ttttttcact cttgttttca
    41401 tctatataat cggatataac gatcgaaaaa ttatcctcaa tatactcttt gcttgacgat
    41461 aattgcgaag aattataaat ctcacttaac aaactaccat agtttatagt cttttctaat
    41521 atcgcttcag ttataaacaa taaatttcta acatttagct tatatgcatg aacctgctca
    41581 acacccgcca atctcacttt atcacaattt gcttctgaca catcttcaaa ctcgatgccc
    41641 gcagaacgaa tattatcgat gaaaacatta aactcttctt caggtattaa agatattata
    41701 ttctcatttt gttctatata ttccttaaat tcagctaagt tagctaaatc tatagtttta
    41761 tttgttaaaa ctgaaatcag tatgttctta aaggtatcaa tattttcatc ttcgcaaaat
    41821 tccaaagttc taacaagcct atccacatta tttttcaata acatattaga atagattctt
    41881 actatatcta agtcaaactc gtctaaaatt tttaacaaat ccttatactt gtcatttata
    41941 tcaactgaat caacaatagc tactacattt tcagtttgtt tttgctctaa acaagtcttt
    42001 aacactttct tattcaatat attgaaacga ctaaaatcag atagttttaa tctgcttatt
    42061 atctcattag gcgtttcgac atccaagaaa atatcaagag ctttgccttc ttttaatcct
    42121 ttcatataga tcatgtcatt tctctttaat atatttgacg tatctacatt aaaattgccc
    42181 ttatagtacc agtatgtttc atccaataat ccgtctacaa ttaaaaatct aattagagga
    42241 aaataatgac tttctacaat gtcaaatcca tcaattgaaa ataatttatc cctttgttca
    42301 gtgttcattt tagatataag ctctttatag ctatatattt caatgtcttt aatctgcttt
    42361 tttatttttt ctctatctaa attaagttta ttcatttcaa cagaaaaatc ttccggtaat
    42421 ttttcaacta atgctttttt ttcattatca gttaaaacat acctattcaa aaaatcatta
    42481 taagtaaaat attgactacc gcttggatac ttaatgtcaa aacgattatc agggttttga
    42541 ctccaatctt ttagaaactg tgacattgtt ttagattgat tattatatgg tcttacatca
    42601 gtcgagatca tcaatgccat tgcttcaaac ttatcattcg caatcctgct atttataaat
    42661 ttaatattat catcgatttt ctctagatcc tgcttaaaat tactaacaat ttttttccta
    42721 ttagactcca attcatcaaa tattgccctt acaaagcctt tatcttcctg caaaagatca
    42781 aactcatttg ggaatatatt ttttaaagta ataagtgcaa atagtttatt actctccaag
    42841 tcaatctttc ctattggtat aattttagag tacacaatat actcattaac tatatttttt
    42901 agaagcctca tatcatccac atataaagaa atatcagcca ataaacttct atcaggggca
    42961 ttctctactt ctttcaaaag ttcaataagt tcattttctg atgtttttga atctaccaca
    43021 gggactatag gtaaaatgaa atcgaagaat ttagttctgt ttttagagta aaataaactg
    43081 tccttaagca tatatataaa tcttatcgga gtttcctttt catcgtttac ttttacatat
    43141 ttgtttaaca gaaaattgag ctctcgcaac tttgtgtaaa tagatgcatt atcatatcta
    43201 tctaaatctt caaaaacaac aatctttgaa ttagaacttc tcaacaagta aactaactcc
    43261 ttaatatctc tatctaatac tgactcatcg ctattattat cattaatatt tgcttccgca
    43321 cctttgaatg ttattttaga aattttaaat ttgtttcctc tattgaatat atacaaataa
    43381 taaaacaatg gtacaaataa caacaaggca cataaaaaca tcaaagatat gccattgaaa
    43441 tttttatacg actcattaac aaacgatata aaattatctc ttattatcca aagtagtatt
    43501 gagcaaatta ttgaaagaac cgccaatgat tgcaaacata tgctcaatat gcttttattt
    43561 gatttaaaac catatttgct aagtggtatt ttctttgatt ctatctgaga taatatttga
    43621 ttgataagtt gtctttctac cctattgtca tcgcctatat cctctgcttt ttgattttca
    43681 ttactacgct tattcttagc accatcagac tctgaattta aagtattcgt caaaggtact
    43741 tcttttagta tatcgtcatc atctttaata ttgtttttat atttacccaa agaaactgta
    43801 attatattgc ttaattcctt ttcatgaaca taagtattcc atactgtact ttttccggca
    43861 ccatatatgc cggtaatagc gatatttttt atactgctat tgccaaaagc ataatcaagt
    43921 gcttccgtat atatttgctt gttttctttt agcacttcag gggtaagtgc attgaattta
    43981 ttatgtttta catcttccag catccatatc acctatcttt ctttatcaag acaaattaag
    44041 tctcctatat ctgaatttaa ttccttacaa attttaccca aaacagaaag ggaaacagct
    44101 tcacctttag ccatctttgc tattgttgtt ggtgaaattc ctgtcctctc aattaaatct
    44161 ttctttttca tatttttatc tatcaacaat ttccataatc tattgtaatt aaatttcatt
    44221 aaaccacctc tttgctccac aaatatggat tttttatata ctattatatc atcttacaca
    44281 aacaacttgc aaatcacaat aaaaaagtcg gtgcagtcct aagaccacac cgaccataaa
    44341 tttatctctc agcctctctg tttgcttctt tcttttcttt tggcttttcc ttatcttcag
    44401 cctgatattt cttgatagct ccaagtacag attctttcct ttcttctcgt cctttcatct
    44461 gttcctttgc ctttagtagc tttgaagaaa gtatcctgat gttgctatac tctttaccgt
    44521 tatcatcaat ggcggttctt atttgtccaa agagcttgac aaaatctccc tgcttaaagt
    44581 cctttggaat atcgcttttt tctccataag cggagcaatt atgatatacc ttattcccct
    44641 catcgtcttt ggatactacg gagaaattcg ccaccttaaa ggcttcttcg ttcttatttt
    44701 ccctttcaac tacatcaacc tctccaacga tatttccaac aatattgata agattatcct
    44761 tttcttcctg aacataaggc aggtttttta tctgtccctg ttcccttaaa tcctcaatca
    44821 tatagtcaaa ttcctcatgc attaaattaa ggctgtcatt gtccatataa gcgtcataga
    44881 gcttgtctaa aacactttca tcattgatac ctttttccat gcttataatc gcctttacaa
    44941 agtccttatg gttatcattt accatatctt ctatttgatt tctcattgtt ttgtaatcca
    45001 tgtttttatc tcctttcatg gcaaaaggga ggttgccctc cccttatctt aaaatttcct
    45061 gttcttttgt tttttgtttt tcttctgttt tgctttcatt ttgataggct cttatctgtc
    45121 ctaaaataga tggcttgtca tatgattttt gtgcggtttc ttctttgcta tgaagattgt
    45181 cctctacatc ataagtggac tcaaaataat cactgtcctt aaaatcattg tcatatctat
    45241 caggaatacc gtcattatca aagtctttag agagcgaatc atagaagttt ccttcatcat
    45301 caatatcaag tcccgttgct gttcttaaat cttcggaatc aacataaact aaatcgttaa
    45361 aagaggacat ttccatttca tttttcatat tccttagagc ttcattttct cctttattct
    45421 cgtaatcaaa gctctccgtt ttgataggag tatcatcaat gtactgcgtc caagttttct
    45481 cctctaaatc aagctcatac tgaataccat gcctttcatc cggtgtattg gtataggcga
    45541 tgccgatatg cttcaaatca ggatacaagg tattaaattc atcatagcta tgattttctt
    45601 cgtactctct gttacagaag tcgatgattg ccctttttac atcttctaca agcggattat
    45661 catttctctt ttcttccact tctcccatat cgaggagctt attcagttct gcaagtctta
    45721 ataccttagt ttttagctca tctgcttttt caaaaggctt ttttaattct tctttggcat
    45781 tttccagttg ttcctttgtg ctgataagtt tttcttcaag cctgtttaat ttctcaggca
    45841 ttttctcaag agcgttatcc agtcttgtaa tgttaccgtc cgcacttgtt ccaagctctc
    45901 ctgaatgctt tgccgcaccg tttagactaa agttatgctc attggtaaaa aagttatagc
    45961 ttacctctaa atccatattt ctatattttc ctataacctt gctctcattg attttcactt
    46021 tggaaatagc ttcaagcagt ctttctccgg ctaatttctt atcggtaatc ttttcgccta
    46081 aaacggtaat ggaagtaaac ttttcctcac cttccacttt aggctctaca cttgctatat
    46141 ctttattaac agcttcaatg agtttttccg ttcttgcgat ttcttcagga tagtttttcg
    46201 ccaccttatc ctccaatctg taacggttgg atttatagtt tgcttcaagc attttaagtt
    46261 ttataacctc attatccaag tccatctttt ctttaatttt cggatcacct gtggcaagag
    46321 ctttaatttc tgcatagtta agggagcttt cgtccacatc ttctgcaact ctgacgggag
    46381 tcttactggt cataatctgt gaaatgaact tctgcttatt ttctatcgtc tgccacaaat
    46441 aggcatcaaa tgtgttttct gtaacataac gataaatatt tactttctca ttttcattac
    46501 cctgccttac aattctacct gctctttgct ctaagtcggc agggcgccat gggacatcaa
    46561 ggtcatgcaa agcaataagc ttgttttgga cattcgttcc ggctcccatc ttctgagtag
    46621 aacccattaa gatacgaatt tctccttttc tagcctttgc aaagagttca tctttttgct
    46681 tatctgaatt cgcttcatgg ataaaggcaa tctctccttt cggtattccc atagctacga
    46741 gcttttctct aatatcatca tagatgttaa attctccatc tccttttgga gtagacatat
    46801 cagaaaaaag tagctgtgtt gacctatttt cttttgtctt atcccaaata gcaaatacat
    46861 tttttacgca tacattgacc ttgctgtcag gattgtctgg aagtagggga ttgataagtc
    46921 tttgatcaag agcaagtttc ttcccatcat tggtaatctt aagcatatta tcttcatcag
    46981 gctctacaac cctatttctg acatcatctg ctctttcaga aaggctcttt aatatttcct
    47041 tttgttcttc agacggctct gttttaataa cttcatagtt agcttcaggt gtaggaagat
    47101 ttatcatatc cgcagtctga atatcagcaa cttccttaaa catactcata agttcaggca
    47161 agttatagaa ctttgaaaat cgcgttttca ccctatatcc tgttccttca ggagatagtt
    47221 caaaggagct ttgtgtttct ccaaaagtgg aagcccaaga atcaaaatgc tctaagtgat
    47281 ttttctttaa actctcatac tgaagatacc tttgcatggt ataaagctct gtcattgagt
    47341 tacttacagg tgttcctgtg gcaaaaacta tgccctttcc tcctgtcatt tcatccatat
    47401 atctgcattt cataaacata tcggatgact taaaggattc tgactgcccg atacctgcaa
    47461 catttctcat tttggtatag agataaaggt tcttaaagcc atgtgcctcg tcaacaaaga
    47521 gcttatcaac tcccagttcc tcaaaggtaa tcacatcatc tttcttaaaa tcatcattta
    47581 atttctcaag ccttgtttcc agttttttct ttgtcttttc aagctgtttt accgtaaaat
    47641 tttggtttct atcatgtttg tattcttcta catagtttac gatttcatca atctgatctt
    47701 ggatatgctt ttcctgatat tccttactca tcgggatttt ttcaaactgc gtatgcccga
    47761 taacaaccgc atcatattcc cctgtggcaa tctttccgat aaatctcttt ctgttcttcg
    47821 gttcaaagtc ttttttatca gccaccataa tattagccga cggatatagc tgcataaatt
    47881 cacgaccgat ttgtcctgtt aagtgatttg gaacaacaaa caaagactta ctgcacattc
    47941 caagtctttt actttccatt gcggaagcta ccatctcaaa ggtctttcca ctgcctacta
    48001 catgggcaag caaggtattt cctccataaa ggcttcttgc tatggcattt ctttgatgag
    48061 gtcttaaatc aatctccgta ttcattccct caaatgagag attgcttccg tcatattctc
    48121 tgttgcggat ggagttaaaa cgctcgttat acagttttac aagacggttt cttctttcct
    48181 gatcgttaaa tatccagttc ttaaattctt cttttaatag ttcctgtttt tgtcctgcaa
    48241 gcatggtttc ttttttattt aagacagaag ttttagatcc atccggattt acaatccggt
    48301 caaatacctt tgtttctttc agatttaagg catcttcaat cagcttatag gcatttaccc
    48361 ttgatgtacc aaaggtcatt tcagcaaggt catttcctct gtccctgctt tttccttcta
    48421 cattccattc gcttgtaagg tttgaaaatt tagccttaat atcccatctt gcatatcccg
    48481 gagttttcag cgtttcaaag atgaatttct caatatcttt aatcggtatc caagttgcac
    48541 caagacgcac attgatttca cttgcttcaa gttcctttgg aagaactttg gtaagttctg
    48601 ctttttggta ttccaaacgg ttcatttcat agcttatcag ctctttttct tttccattct
    48661 caacaaagcc aagatgagga agttctcttt ccgtttgtct tagttttgat agataactgt
    48721 ctacaatggc aatcttgtcc ctgatattcc cacttaggta ttcatctttt gttacatagc
    48781 catatttata tgaattactg ccgtttgcac aagcgaaagg caaatctcca tcttcaaggt
    48841 taaaggataa tggtctataa aagttttgtt cttctctgat gtttagataa atttctcctc
    48901 taagttcttc tatcaaagtt ggtctgtctt tacctgtaag gctttccata tactcaaaat
    48961 ccacatagcc tttttcagat accgataaga caagagcttc aagggaagtg tccacatggt
    49021 ctatgacttt ggcttttgta atggttctct ttgagaaaat atcccccttt gccttgacgt
    49081 tttcttcttc atcaagaatt tcaatggaag atacaagagg gaaattgcta tcctctttta
    49141 aggctctggt attgcttaaa ttatttataa agccatgctt ctttgaaaag ttgtcataga
    49201 cttcattaag cttttcttga gctttcttta cctcatcatc ggaatagtcc tctttctgct
    49261 tgtagataac atctttaagg gcagtattca gttcaagata gtccttaatc ttttccttat
    49321 tcttatccgt tatctctttc ttgatgaaaa gggagttttc tctgtaatag acttcatcat
    49381 caataacggt ataggaaaag tttttgacat catccgttgc aggaattgaa gtgatttcat
    49441 catctaaaag ctctatttct tcataagttg atcctttgga tatttcttca cttgcttttg
    49501 tcagaagctc ttttaagtcg gcattttctt tcggcaggca cgcaagtgtg tttccaaatc
    49561 ttcctgaaac ttcacgcatt gtgccgagta cctgctcagg atgatctaca aaatatttgt
    49621 tataggtaag accattttca tcttcagcaa ggtgaatcca gtcctcatct ctttctctga
    49681 tactgtccct tttctttagg aatataatat ctgaggttac ttctgttccg gctatgccct
    49741 taaaggtatc atttggaagt ctgattgccc ctaaaaactc tgctcttgct gcaagatagc
    49801 gtcttacact ttcatccttt ttatccattg ttccacttga tgtgataaag gcgataatac
    49861 cgccgtttct gactttatca atggatttcg caaagaaata atcatggata aggaagttat
    49921 ttttgttata ctccctgtca tttaccttat attctccaaa aggtatattg ccgataaccg
    49981 catcaaagaa gttattggaa aaggaagttt cttccagtcc tttaatctgc acttcacttt
    50041 cagggtatag tagttttcca attcgaccgc ttaccgagtc aagttctatg ccataaaact
    50101 tggacttatt catttcatca gggatattgc ctataaagtt tccgatgccc attgatggtt
    50161 ctaaaatgtt tccctgttta aatcccatat ccgaaagcgt cttatatatt ccgtcaatta
    50221 cggttttcgg tgtataaaag ctcgttaaag tagattctct tgcagcttcg tattctgcat
    50281 gtgataagtt ctcatttaga aaagcccttg cttctttcca ctgaccttcc ttgctttcat
    50341 caaagacttc ggaaagtccg ccccagccta cataccttgc taaaacttcc tgagctgtac
    50401 tgtcaagctc tctttgtccg ctctccactc tgttaagcat ggaaattgct tcaaggttat
    50461 tatttaacct ttcgcttgga cttaactttt cagggagcgt ttcttctgta attttaaagt
    50521 tatgagcttc cgctttcctt atttgagttt cctcagtagt ctgctctggc tgtttatatg
    50581 tcaggttttc aaataccctc tcaaggtcgc tttccagacg ataaggaatg acatcgaagc
    50641 ttgttatcat cccgccaaaa tactcggtgt tgtccttcac cgttaccgta tttaggttct
    50701 ttctcatatc atcaaagcgt gttatggtat ggttttgtcc ttgtatttaa cttcatcacc
    50761 gacaataaag ttcggtcttt caagacttat tttattcagc aagtcctcat tatctgtaaa
    50821 gtctacaatc ggaatttgat ggtttccact tcttaccgga tcaagccaca aatcatatct
    50881 tcctgtgatt tcatttttag aaatttctct gactttatat tcttcatgat taaaatagac
    50941 ggtatcgcct gctttaactg caaactcttc taaaaggctg tcctcttttt cattcagttc
    51001 tacttcttct ctttctttga ggtaatcaaa taaggtagct tgaactgtgc cacgctttgt
    51061 agcttcttct gtttcttcag gtgcttcaag ctctacttta tcttcaaagc taagttctcc
    51121 attaaagaca aactgaagct cctgctcatc catttgtttt ataagctcta tatctttaag
    51181 ttctctaaag gtctttggaa aatcctctaa aatgagcctc tgggcattta attctttcag
    51241 ttcctcaagg ttaaaatatc cccattcagg ctctattcca agaacaagtc caaaggcatc
    51301 accgctttcc ctgtcatact ccgtcatata ccaagtccaa tttgaacgaa aaggaataat
    51361 atatgctgca tgaacctgct tatccgctaa atctacatcc tcctgtgcgt aaatctctgg
    51421 cactctttca agaatttcat caggcattag atttccagga tcatttttag aataatattg
    51481 cggttctttt acttcttcta tctctgccgt actttctgtt tccttttcct caaaataaag
    51541 ttttttagaa agcagctcat caatatgctt tgcaacactt gtccaagtaa ggaacacatc
    51601 attacaatca ttcttctgta atttaaaacc ctttgcatcg tgccattcat cacttcccat
    51661 tgcacctgac acaacgtgag aatgtcctcc gattccatat tcatctttta ggaaattggc
    51721 tttttcctgc aaagtatgat tttctttaaa aaacttggtg attcgttctt ttcctctatc
    51781 aacgccgctt cctcttgaaa ggctttcaag gacttcatct tctgtaataa agagctttac
    51841 cttcggaagt tctgtcagat tggtactata ttcctttcgt tgcagctcaa gttcttgcaa
    51901 cttctgataa agactatcta ccttgtgata atgatacctt aatacatttc tgctttcttt
    51961 gtatccttct aaaaacctgc tatattcttt gattgtttct ttcagatatt caggattttt
    52021 taatgcttca gataatcttt tcgtttcttg cggaaagcca ccacctcttt caaaagagtt
    52081 gaaatatcct tgctctattc cttcttcgct taaatcgtgc gttagatacc ataaggattc
    52141 tgaaattcta tccctttcat agtcctgtgc ctctaaaagt tctacatttg tagcaaactc
    52201 acctctgtca agaagttcat ttatcctact tgctgcatca ctccaactta aaatttgtgt
    52261 attatcctct cttgccgatg ttccataagc taaatgaata cctttatccg aataccagga
    52321 agatacttct ctttcatcaa tgtaaaatcc gtttccgcct ttaaaggtat ctttgaggta
    52381 ttctcccaat tcttctatgc tcttgccttt tgaaaactca gcaataacag gaagcctacc
    52441 gccatcatga tttcctccgt taataaggac ggtatctata tccttctcag ttagcggaat
    52501 agtaaggctt atctgtccat aagaattttc gggtaaagaa aaagaagcct tttcagcttc
    52561 tattatccct ttatccgtat tgtcttttaa atctccacta cttccttgat ggtcatttct
    52621 ttgagagctg aaatcatcgc cccatactgc ggattgttct cgtcctctat cttccaagct
    52681 gctatcaact ttggcttctc tgctctcata aactctactg cctgtttctg aatatccatc
    52741 aggtgtcctg tcagcttctt ctccttgtat agatccaaaa gcatctcgaa gtggctctgc
    52801 tcctcgctct gtgaaaggta attcagcctc atcactgcgt aggtcggatt cggatacttc
    52861 cttataaagt ccgtctgttc ctccaagctg tttagcgtat tctccctgat tttttctatt
    52921 atctcgtccg tactctccat ttcggagaac tcgctcgttt tcatttcttt cctgatcatc
    52981 tcgtcgaaat acattttctt ctacctcctc taattcttct ttaattttat tatatcccgc
    53041 ttcttttcct attaaaactt ctttttgaag ctcaagctct ttgctttttt gaatggtttc
    53101 atcaataatc tttccgctaa tatccgatac actttcacca aggctcatta aggatatgct
    53161 gtcaaatctt tgaaaatttt ctcttaaaag ctcataatcc atcggataat ctaacttaaa
    53221 tcttgaagct accgcatagc ttaccgagtc ccttacaaac ttggtaaatg atattctatc
    53281 ctcatccgct actctaagtt cattcattaa ggtatctatt ttttcatcac cgtagagtct
    53341 gcttaaagaa aagatgtttt caagtgtgct ttcactttcc tcatagccct cgctttttat
    53401 catttccttt aagacatctt gatgggcttc tttatcaaat ctccaaagat tgacctcgtt
    53461 gacatccctg ttttttgaaa ctgtctggct tatatcaaag atatagtcca cctttttata
    53521 tgtgccgtaa tcctctaaaa ttggtatccc tttctgccct cgcataaccg ttcggttaaa
    53581 gcgttccctc cagtagtcga acttggcaca ggctgtcgct tcaggatttt tatcatatat
    53641 acttaattga cttctaaaat catacctttg attgtttccg acaactttta ggagctttag
    53701 atattctgct tcattataca aaacatcttg ttttattagc tccaaaatgt tatgaaaatc
    53761 atttattcgc atttttacct ccttcttttt tcaaacaaaa aaggcggtta gattttactc
    53821 taatcacctt cgctatatac caaatattat tactctattt caatttttta attgattcac
    53881 tttcagatag tatcttcatt tgttcaatag ctattgcatt taatttttcc aatctttcag
    53941 attggctcat gccttcattt ataaataccg cattaagatt ctcaagatta gaaaggcaga
    54001 caagctgtga tatatccgca taatctctaa tattgccttt taaatccgga ttttcatcac
    54061 gccactcctt agctgttatt ccaaatagag aaacattaag aatatccgct tcacttgcat
    54121 aaataaaatt gattttttct tttgaaagtt tatccggtac aagtttgttt ttaatggcat
    54181 ctgtgtgaat tctataattg atttttgcca aatttctctt aatatcccat cctaacttct
    54241 tttgttcttc ttcctttagg cgttcaaatt ccttgattaa atataattta aagtatggcg
    54301 atacccaaga agcaaactca aacgctatat ctttatgagc ataagttcca ccatatcttc
    54361 ctgctctcgc aacgataccg atagaattag ttttttccac ccattgcttg accgataata
    54421 taaaacggtt aaatcctgct tcatttttaa ttccctcgaa ttcgggggaa ttaaaattcg
    54481 tgttatacat ttcttcccaa atacctaaaa actctattgt attcttgttt ctgagccact
    54541 tttcaatcaa agcagaaccg ttctcaatat ttctaaccat atccgttaaa gaaatataat
    54601 ctctattgtc tatggcaata atgctgattt ctgaaccttc aacatttatt ttagacatat
    54661 aatcacctct caatcattaa attgattact ttgcattata gcatttttag agcatttttt
    54721 ccacgctgaa attagtgctg tcttacttgc gatatgtcaa aaccgcttct tttatctcat
    54781 tttcaatcgc atctaaaaat tctttcttag aggatttacc ctgagcaata tcagataatt
    54841 ccatttccca ctttgctgtc gtttctgccg acttaaaggt atctgctaca atcgttacaa
    54901 ggctgattcc tttattcgtt gcaattagat tcttcttatc tctttcgaca aatctcttaa
    54961 agattagatt ttcaataatt cctgcccttg ttgccggagt gccaagacct tttctttcca
    55021 cctctacacc tttttctaag gcatcatttc ccgcaatctc catagacttt aagagcgtat
    55081 cttcagtaaa gtgtttcgga ggttgggtaa atttttcttt aacctcttta ttttcaacgc
    55141 tcaaaacttc accaacactt acatcgggca atacagcatc ttcactcttt tttgatttgt
    55201 attctttaag gtatttgcta aagccttcat ccttaattac cttacctgaa cttgtaaatt
    55261 caaaaccgtc aaatgaagct acaatctttg ttgtattttc aataagcgga tagcctacac
    55321 ttgcatgaaa tttatcggat ataaggaagt aaacttttgc ttcacttaaa ggtaattcag
    55381 aaacatcttc ttttactgaa ctgattgtcg gtatgattgc atgatggtcc gtaacctttt
    55441 tagagttaaa tactaccttg atacgctctg tatcaaagtc atttttaccc aaaatgttgt
    55501 tgactgtact cacaatcata tcctctgtta aacatctgct gtctgttctg gggtaagtaa
    55561 tcagtttctt ttcatacagg ctttgagtat agtcaagtgt ctgcttggca ctatatccaa
    55621 aatatttatt gcactccctt tgaagcgtag ttaggtcaaa aggtaaatca ggctttgtaa
    55681 ttttttcttt ttgaataaca tcagtaattt caatcttatc gcctactaaa cttataagct
    55741 gttcagcagc aacttcatca tcaattctgt ctgtggagag tgtaaatcca ttcatagaaa
    55801 gctctactgt gtaatatttt tctttctgat aatttgctat ctcatcatct ctttttacaa
    55861 tcatggcaag ggtaggtgtc tgcactctgc caacactgta attttgctga tacagacaag
    55921 agtagagcct actaatattc attccgacta accaatccgc aatagctctt gcctgtgccg
    55981 attcaaagag attatcatag tcttttccgt ctgttaggtt atcaaaaccc tctttaatgg
    56041 cactatcttc cattgaagaa atccaaaggc gtttcatctt ctttttacaa ttcacttgat
    56101 tatatacaag tctaaaaata ctttctccct cacgccctgc atcgcacgca ttgataaccg
    56161 tatcaacctc cttatcattc atcagctttt taaggatgtt aaactgcttc ttggttgcct
    56221 ttgctacttc atacttgtag tcgctcggaa taatcggtaa atcagccata ttccacttgg
    56281 cgtacttttc atcataagca tccggatttg ccatttgaat taggtgtcca acgcaccagc
    56341 tcaccctata tccgtttcct tcataatatc cgtctttctt tttatttgct ccaataacct
    56401 ttgcaatgga gattgcaaca ctcggctttt ctgcaataac taacttcatc tgtgttttcc
    56461 tcctgttata aatcaaaata gggcgaaaga tgttactctc ccgccctaac tttgcaccca
    56521 aaataatatg tttttaggtg cgtttattct tcatcttcta cttcatctgc atcatttatt
    56581 tcttcctcgc tttcagattc agaaaagaaa tcatcatctt cctcctctaa ggcttcaagt
    56641 tctttatctt ctttcttttt cacaacctta aaatagtagc ctgctcctaa tgcaccacct
    56701 actacaagaa gcaaaataat ataggttcct aaattactct tttcgtcctt cttctcaggc
    56761 tttacttctt ccttaacagg ttcttctttt actacttcct gctttggtgc ttcttttttc
    56821 tccgccatgt taagcaaatc atcttcagat acttccgtaa gaagcattac attctcacta
    56881 tattcatcat gattgatgat taaatgaaaa gtcttaccgt ttttcgtttg aaaggtaata
    56941 aactgccttg catctgccga atactgatcc gtttctttgt tatcgctgct atctccatga
    57001 tgaatcggat actccttatt tgcattatct ttattctccg taacggatgc tctcgccttt
    57061 gacggagatg aagctactcc cttgttggtg tttacactct tacttgcaga ccccattgat
    57121 gaatcctgac tgttattcgc aggagctttt gccgtcaact tattgggata gcgaacttcc
    57181 ttttctttct cctttacttc cgttttgcct ttaccggtat cctttgtagt attacctgag
    57241 cttaccgaat ccgatgagcc tttaccggta ctacttacag aagtctgtgg tgtttgagga
    57301 gaaatacctg aacttgtctt aattccggaa ataggactaa tcggtgtaac tgattgtgat
    57361 gttacaggag ctttatttgt ttcagttgcc tttttctcaa gctctttcac cttttccgtc
    57421 agcttatcta tttccttttt catatcttct gataagtcct tatttccctt atctttcttc
    57481 attttttctt tcaggctatc aatttcatct tcaaggtctt taattttatt cttttgctta
    57541 tcacttaatt tgtctttgtc cttaagttcg caatttaact tatcaagttt atcctgaagc
    57601 tcttttgcct ctttttctat ttttgaaata tcgtctttag aaagctctgt ctgcgttccc
    57661 ttatcttctg tctgagtgca ttcatcctgc tttggctttt cttcttccgt ctgcgtttcc
    57721 ttatccttaa cctccatctt tgctacctta cggataatct catcttttcc atctcccttt
    57781 acctcataaa acagaaattc atcaatgaat ttcatatcat ctgggagcat tggaagatct
    57841 ccgctatcaa taagttgtcc tttctcagcc tttatctttt cttccttaaa gaccttttca
    57901 tcttcaaaga tataccttac atttacttca acttccgttt gaacagcttc gttttttgtt
    57961 ggagcttcag atttttgctc ctgtgcataa acaaccgtcc aaagacctaa aatacaacta
    58021 atacttacaa ttaccgcaag tgctaccgtc caaaacttat tattcttttt caaactggtt
    58081 ttcatttgtt ttctcctttt tcatttctgc tttttgtctg tttacctttg ctatcaaatc
    58141 gctgattgtg atgttgttct ttctgcaaat ggcaatgatt tcttcatttt caagctcttc
    58201 ttcacgaatg aataaaggct ccaattcttc atcaatcaga gcctttttat cctttaactt
    58261 ctttattctg ttttttactg ttgtaagttc ctttttcaaa ttgttacctc ctatttcttt
    58321 acatttggcg gaaaaccgaa tcctacggga tggtgcttac aaaatgttgc tatccaatca
    58381 tctaaggtag ttactcttat tcgaccgatg ttatcaatca cttttccatc tccaatgtaa
    58441 atacctacat gaccataggt aagccctgca ctgcttccgc tactgctgct ttcaactgcc
    58501 acaagcattc ccacttttag ctttgacctg tctgatgtaa aggtatagtt tcggtacata
    58561 tcacaggcat tcccgcctat atatccaagt cctgcatttt gatagacctg tgatacccac
    58621 atggcacacc agcctgcacc cggagatggc gtaatgtatg cagcattaac aatcttcttt
    58681 tgtacttccg tagatgcctc atactctttt ccaccgccga tacctccatt tgcactgata
    58741 aggtcagaat taccaaaggc ttctctcata ttgccttgtg caaggaacaa ggcttcatag
    58801 tgctttagat tatcgggata gtttgcaaag acctttcgga taatactgtc catctctttt
    58861 ttatgaagcg ttacaatgag ttttttatac tcataaggtt cttcgtggct ttcggtatat
    58921 tcattgccat cttcatcggt ataggtttcc gtaaccgtcc tgtatctgat ttcaatttct
    58981 tccctatact caaggtcata catggactca aataattctt ttaatatgga ttctacttcc
    59041 gatacactct ttacctctcc gcaccttgat gtaatgtagg ataaaagctc atggacatta
    59101 tgaccgatgt attctgtatt atttaagata tattcatcat atccaggata attttctttc
    59161 acatagtcaa cttcactttg aagctcaccc tccatatctg aaaatttctg attgatttca
    59221 cttaggacat ttggctttga taaatagctt gttgtaagca cagagcttgt agagttcata
    59281 aagcctgtca ttcccgttcc tgcaaagtta atcacaaaag tccctaagat aatgatacct
    59341 atgaaaataa gcattagtcc ttttgctttt cggataatca tatcctttga gcttttcagt
    59401 gttccgataa gtccctcttt aattcgatct ctaagccttg acttattctc acgagaaatt
    59461 gctgccttta cctgattttt cttttgaaat cttttatatg cacttgctct tttatactca
    59521 tccgtctttt tcagttcctt tttggcatca cgaaattcca actttgactt acgctttctg
    59581 attttatagt ccttatttgt aaggtcatag cctcttttag ctcttttctt atcagagtac
    59641 ttctttatgc catgaatgag cttggagctt gtatctgctg tcttttctcc tgcttccact
    59701 ccttgatttt catcacttcc atgagacaag taatctctta cagtttcact tcctttagca
    59761 agtcctgaaa gggcagatac ctttaccatg tcttttttta gctttttctt ttggtctttt
    59821 gataggctgc tataaacttt tccgctgaca gcatcttttc ccgccttttt atcatcagcc
    59881 ttatttccct ttggtgcatc gtcctttttc cttgtataaa ggctttcaga atagttcttc
    59941 ctcttgtacc tgcttttttg agtcttatga tttttaaagg aattttctaa tgatttttct
    60001 ttatgggaaa gattatcctc cacatcatag gtcgattcaa aatagttgct gtctctaaag
    60061 tcattatcgt atctgtctat aatcccgtca ttatcaaggt cttttcctaa aggatcatag
    60121 atttttccat ccttaacctc cgtaatataa tctgatcttc ccgtttcaat tgcggaattt
    60181 acgtctccct tatctgaagt tctatatttt tcgtttctct tggatgttcc ataagacttt
    60241 tcattatcag cacttacctt acttgttttt tcatgcactt tatcctgaaa ccgttctttc
    60301 tcatgaacga ttttacctct gtaatcatcg ttatgtttta gcttactttc ttcaggtatc
    60361 gtatctgttt tactatgaaa catctctctt tcaaggcttg ccttatgcct ttccttaaaa
    60421 tcctttttca gcttctttcc cataggctac ctcacttctt ccggcttggt agtcatcttc
    60481 tgatataaaa ttgtatcttt cggaaactta tcaatgaaag gcacaatggt atttccaaag
    60541 aataagagtc cctcaccttc atttgaatta gtaacatatc tgagctgtgg aagtgagatt
    60601 ttaagttttc ttgcaagtat ctccctatct cctgatgctt gattaagcat taagacaaag
    60661 tctgtattgt caaagatatt ttctatctcc ttactcataa gtaggtcttt gacattctgc
    60721 gtaatacctg ttggaatacc tccccattta cgaaatcttt tccaaatctc tacgaaatag
    60781 gatgctgtct gctcatcttt taaaagcaaa tggaactcgt cgatatagta ccttgtagcc
    60841 ttgtttcctc tgttttgtga caccttattc cacacctgat cctgaataac aagcataccg
    60901 attttcttta attgacttcc aagctcctta atatcaaaac aaaggagctt cttatttaaa
    60961 tccacatttg acctgtgatt aaagacattg agagaccccg atacatagat ttccatctct
    61021 gttgccagct tcttaccgac cttttcttcc tgccctttta acatatcgta taggttttgg
    61081 agtatcggca tattgtcagg agtaggatgt tcaaaatact tttcatagat tttaggaagg
    61141 cacctatcta taacggactt ttcttctgct gtaagaccac taccgcctac tacaagctca
    61201 agcatactca tgataaagtt tgccttgtct ttcagcggtg catccccatc accgtagttc
    61261 atgtttatat caagaggatt caggtaatcc ttcgacttac tgctgacctt aatgacttct
    61321 cccttaaact gccttacgag gtttccatac tctccttccg gatcgcagat aatcacatca
    61381 tcatctgtta ctaaaatcgc atttgccatt tctcttttgg cactaaagga cttaccgctg
    61441 cccggagttc cgaggattag accgtttggg ttctttaatt tctttctatc tgccataatc
    61501 aggttatggc ttagggcatt tagtccgtag taaagactat tacttgaatt gataaaaagc
    61561 tcctctgtgg taaatggcat aaatactgcc gttgatgagc ttgtcaatcc tctatctatt
    61621 tcaatcttat ttacaccaag aggcagcacg ctcactaaac cttgttcctg agaatggtca
    61681 agtcttttca gcttacagtt atgcttattt gcaatggagc ttatttgagc aattgtgtta
    61741 tcgagctttt gcactgtcct tgcaaagttc ataaagacga tacttaccac aaacattcgc
    61801 tcatctcttg tctgcaagtc ttttaagagg ctctttacat cctcaccata ggtaattaag
    61861 tccgatggaa gaatgtccat atcataaccg cttcttaccg ccttcttatt ttcctcaatt
    61921 ttcatcttat caatatcagt gttttttcgt tttaccatct taatggcttc cgattggtcg
    61981 attgccctaa tatgaaagga aatattgatg ttatcgtcaa tatccaaaaa ctcggataac
    62041 atcctatctg aaagctcact ggcaaggatt tgaaaatgac ttgttgctcc gatgaatttg
    62101 ccgaacttaa agtatctact cggtgtaaag ttaaactcat caggcacaat atatgtcttt
    62161 gtgctttccc ttttctttag gtctttgtag gaaaatttaa atgttttatt tggatttaaa
    62221 acatcatgaa gtatctttag cctttcttct ccgtttaggc tttctgctct tactcccata
    62281 cttttaagac tcgataatat atctatctcc agtctttcaa gttttgatgt tgcctgttct
    62341 aaattatccg cttccactgt aaaggttaca tactttgatt ttttcaatcc gttatttccc
    62401 tttacaatct ggcttttaag catctctcta aattcaaagc gtatatcgtc gaaaccgtcc
    62461 tttttatccg gtatctgaat tgccgacttc atttcttcgt ttcgtccgag ctgattgata
    62521 tatgaaaact caatgctgat acttggatca aaagagttta ggaagtttgc aaattgatta
    62581 aaaatcaagt ccctatcttc atctaaggca agctgatagt taatgtcctg aaaggctata
    62641 cttttactga agtgcttttc atcaagctgg catattccgc tttttaaaag ccttagatag
    62701 ggaatggtat cttctaccgt atatcttttc ggttctttct taaagataag gtcaaggatt
    62761 cctcccttat ctttttttga cttgcaatta cttttcttta agtcccgctt ttgacttctc
    62821 aatgcctttt cgttttgcat gagttttatt tgctgaattt ttcttttctt gttcaaggta
    62881 aacctccttt ctcactctct tttgcggttg ataaaactta tgaagataaa tgtacttaaa
    62941 gtatttctca aatgtcagtc cgtctttttc aaatagtgtg atgaaaaaga taggaagcgt
    63001 ggatacgata aggaatatga cagctatgtc atttggcaca aacttcctca taaataaata
    63061 gactggtatt ccaaccagtc ctgcaagtgt gaagcctatg agctgccttt tcgttaggtt
    63121 aaaagcaacc tttgtcttta ccctatttaa gtctttaggg attggtacat atgccatatc
    63181 ttacctccca tcttctttac cctttgacag ctcctcaaag tgttcatata cagagccgat
    63241 ttcttcctga atagtcgcaa gctgttcgtc tgtgttcttg ttatatcttt gctgcattag
    63301 gtaaaaatcg ttatggcagc gaccaatgtc ctctgttttt tcttccaatt cttccacctt
    63361 attatgaagc ctgatcctat caattatcgc cataatacct gctccaatta ctactataaa
    63421 tactgttttt cttttgttca tattaccctt cctttctttt agtgtgcatt taatacgctt
    63481 ttggccagtg ttccgctctt taacatcatt aaccctagca aaaccgcata tccaagtatc
    63541 gtaaaggtac ttgtgtgtat atctgttatc tgtattgtct taactaatac tgcgtatatt
    63601 ccaagacaaa ccattaaaaa gagtccttgt aaacctatgg caaacaatcc tttgatatag
    63661 tttgttccaa tctgtcccca ctctttgttt cccattgtgg caaatggaat ggctgaaatg
    63721 gatgagtaaa cataaatctc aaacattctt ccgtaaacca caagcataat cacaattgaa
    63781 atgacctgta ttgccacctt tataagcgag gtttcaaaga gtatcatgac aagctctcca
    63841 agacctttat cctttaatcc atctaccatt tttactatct gatctccgga gataacggca
    63901 gaagtattga ttacccctgc cgctttattt accatgtgct gtgccacatc aaagaccgcc
    63961 attgaaaact caaatgcatg tgatactaac catacagcaa tccacatctt gatgatgtac
    64021 ttgaaaaatt caaaagtatc tgtatcgtgc atattgttct tttgcattac catattgata
    64081 agctcgatac aaaggactgc tgtgatgatt agccctgcta tgggaataat gacggaatcg
    64141 ttaatgcttt taataaaggc aaatacatct ccgttccacc ccataggagt ttttcctaca
    64201 tctgttgcaa ctgcaccaac tttatcgttg atgtcaagaa acatggactc taagtttgct
    64261 tgaataccgc ccagtagaag ctctttaaag aattcttcta tcttgtcgaa tattccaaac
    64321 atctaagctc tccttttctt attacttgag tacatttgca agaagcggaa tcagcttaag
    64381 tccgataagg acaatgcctc ctcccgccat aagctgcttg atgccctgag atttcgctcc
    64441 cggattatca ttaccatatc cttccataag gttgataact ccccatgctc caagtccagc
    64501 acctactgcc ataactaaaa tctttaatac atttactgcc tgtgcgaaaa attccataat
    64561 ttattcctcc tcattttctt ctttcttctc aatcttgtta tatgacttca ctacaaagtt
    64621 tttgtaagtc tttccctctt tttcacgctt cttaaagtag ccgaatacat gaatcaaatc
    64681 gcctttttca aagtcctctg ctttctctgc tttttctccg taggctgcac aattgatgta
    64741 ctccttgccc tttccatatt tttttacaag cgtaaagttt acaacttcta cttcttcacc
    64801 ctctttttca aaacttgaga aagtaggttc tgccactaag ttggcgttga tgttaatcat
    64861 ttcttgtttc atctttttaa atttctcctt ttcatttcaa taaaaaaaac gactggagtt
    64921 tttcttttcc aatcgctgat actcttacta tttagttttc gtttaagtgg gatttctgat
    64981 ccttatcatc ttgactcctg attttgaata aaaaaacagc aaatcttttt aagacttact
    65041 gcattcttgt aataaccgtc tctctattta attttgcttt tccttttcgc ttcatatagc
    65101 tttctatgtc aaacaaattc ttcttgtcat aatcctcaag cagcttataa ttcttgtgct
    65161 ttgtaatatc gtatttatct gaaagaaaag gtctgacacc tctaagctga aatatacatt
    65221 ttccaccgtc cattacagta atctcatctt gactcatcag ttccttacca gtcttttgat
    65281 agtttaaacc aaagctcttt tgatttgacc ttgtttccga cgtgttatac aggtcgatag
    65341 tttcttttcc cagtgtttca gacaattctt ttagcgtagt tttctccttg ccaccaagaa
    65401 acaaggtact atcacagtta cctacgattg tatcagcgtt atccttgtag attgccttta
    65461 gctgagattg tgcttgaagt atgatacttg ctgaaatctc tcttgaacgg attgttgcaa
    65521 ttaacttctc aaacttagga attaagccga tattagcgaa ctcatcaagt agacacctca
    65581 catggacagg taatcgtccg ccatatacat catcggcttt atcacataaa agattaaata
    65641 actgtgagta cataatggat actacaaagt taaatgtatc atcggtatcg gagataataa
    65701 caaatagtgc tgtttttcta tctcccagtg tatcaagctc aagttcatcg tcactcatca
    65761 agtccctaag ttcctgaata tcaaagggag caagtcttgc accacaagaa ataagaatcg
    65821 atttggcagt ttttcctgta acaacttgtc aaggactttc taatcatttt tatgggcttt
    65881 tttatctttt tctcgctcca tttctctaag cattatcctt ttcaatttat cttgcatggt
    65941 ttcagtcgca ttttcattaa aatggactac aacctcgtaa gttgcccttc ctatcttctt
    66001 tatggtcttt gttccagtat tttgttcatt tctgttttcg tgcatattat tttcctccta
    66061 ttagttgcaa ttaaaaaaga cgatagaatt ttatttctac cgcctttcgc aagtcttata
    66121 gctattcatt gaataacgct ttaccattta catattaaat tttcaaatcc ttattgttca
    66181 gcattccgcc aaacatcgta tgatacatat ccttggaaga ttcctctatc tttgtaatac
    66241 ttgatatttt atttcctgca tcctttgatg aagctccgca aagataaaag gcttcactgt
    66301 ctgttccata gtcaatggca atatatctat cgtgatactt tttacctgca attttcatct
    66361 tcagattaat attagggtaa tcttttctaa aatcgttaag gatatttttt gtaagcatat
    66421 ccttgttctt cacattgtcg ctaaagacta taatttcaac attgtctttt gcagccctta
    66481 ataattctaa ggttttcaag cctatatagt tgtctatcac ataaatgctt ttctttgcag
    66541 acttatatat tttggtatag gcaacatctg cttcaatctt atctccgttc attaaaagga
    66601 aatgcttgta tgtgtccgga tctataaaat tatccataac ctttttcaaa tcttcttttg
    66661 tagccatttg cgactttatt tcagctatat cctttgtatt ttgatttgtc tgtactgcta
    66721 tttgaactaa ttcttttgaa ccgataaaat cttggttttc aatgataaaa tctttcattt
    66781 gcttaaatgt tctaactaaa gctctgcttt gcttaacagc aagttcacct cttaatacag
    66841 tcatcagcat ataaatacct tgttctgtaa aggcataagg attgtattta atattacttc
    66901 ctctaccagt ccctctgttc aaggtgaaat ttttgcacct tgaaagttct accatttctt
    66961 cgtccgttaa ttggaacatg aagtcttcac cttcaaattt ttctgcgttg tttttcacct
    67021 gtctattaaa gttttttgtt tcataaccat atatttcagc taaatctgca tcaagcatta
    67081 ctttttgccc acgaataaga tatatttttt cttgtatagt tttatcatct acaataacta
    67141 tctctttatt ttcttctgcc atgaaatgca cctccaacat tatctaaatt cttttccaat
    67201 tcgccacgca ctgcgtagct ttttgaataa gtcttatatt cttttatatt tttctactcc
    67261 gccttcagct tttccgatgt gttccacatt ttttacaagt cccttattta cattttcata
    67321 aaaccatctg ccaatcaatg ccggaggtgt tgcgattaac tctctcaaaa caaattcttt
    67381 gtcctttggt aaagagctaa ttttgtttaa taaggtagta tataggtcag catagcttgt
    67441 attttcttgt aaactactac acttacaata ttcagtaacg cttgggaaac ctccctctat
    67501 tgctttttta gttaaaattt caagttcttc atcggttaca gtaaattgaa ttcgcattta
    67561 tatatcctct ccttataact gagtttatta ccatatcatt atcattttat cataaatacg
    67621 atattttttc catactgcaa ttttaagccc tattttacac ttagctatag tctgatacct
    67681 attttatcat taacgctcta aaaacacctt tccaccgtct tatgcgaagt ctacaagtgt
    67741 tcacccttgt cataatcttc aaaggtatat acttttgatt tactgctctc ctttaatttc
    67801 cctttgtctt gttcgtacca atgaactaag gtcgcataat ggtctttata gtttcttccc
    67861 gtgctttgca tataggttga cagcttctct atcattttat ccctatgacc ttgcatttta
    67921 tcctttaatt ttccatattc ttcatcagtt aaggaaacat ttttatattc tccataaagg
    67981 ttgggggata ttttttctat ctccccctct ttttctaact ctatatctat ctctttatct
    68041 atctctatat ctccgttgca gttttgttgc aaaaggttgc aaggtgttgc accagtgttg
    68101 cattgcaacg ctttttgtcc tctcgatttt cttgaacgcc ttgtagaagc tgtttctgaa
    68161 cctataagac ttgggatttc tgttaaaaaa tactcgtcat tttctgtgat tatctccatc
    68221 aagccttgtg ctataatata atttactgta accattacat catcttccgt ttcatcaatc
    68281 gttaaggcaa tctctttgat aaagtctgtt tctactccat cataatacag cttcccacta
    68341 tcttttaagc taagtaaaag caatttaaga tagatgattg tataggtatc tcctcctgat
    68401 atttttctta gccttttgat tctcttatct gtaaaaaaat cttctttcaa ttttaaccaa
    68461 tagtatcttc tgttgtctgc catttttatc tttcctcccc tttattttta taattttctt
    68521 tagccttttc cttggctttt tgtttgtact gcccctttat ttcctcttgc tcttggaatt
    68581 ttttcagttg tgcaatcaca cttggtttat ctcctctctt aattgccttg tctatctcta
    68641 tgcttaggtc tattccatac tcttcattga caatctttac tgcatatttg atatggtcta
    68701 tctgcttaaa ttcgtcttga actttagctt tatctttggt tagctcttgt atctgatttt
    68761 caaggcttga tatttctttc tgccaatcac tcgactttat agctgatgtt ccagtaaatt
    68821 tttctatgat ctttcttgct ctttggtatc tgtctatttc ttttttatgg gaattgtaaa
    68881 aactgtcttt gaatagtgtc ttgcttttgt attcctgata gacttctttg ttttctctga
    68941 tagcgtctat gcagcttaca cattgattta ggtcttttat tctttgtgtt ttatcttgaa
    69001 tatcaccact tatcttttta ctttgctttg ccagttcaaa gacttttcct tgtaggtctg
    69061 ctatggtttg aagatgatta tctttcaaat agtagattgc ttttacaaat ctctttaggt
    69121 ctgcatttcc cttttttatc tgtccgtagt aggataaatt ttttgttttt tctccctgta
    69181 tctcgttgta gatagaaata tactcataga ggttaaagag ttccgctttg ttctccagtt
    69241 catctttctt ggtctgttta tactcatcgt attttgcttg cagatttcca agtaaagaat
    69301 ctatccaaga ggtgatttct tttatcttgt tcttgatggc ttttactaaa gagttatgct
    69361 ttttgatttc tctattgata tttcctttgt cggtttcgat tccttttttc tctaaggcac
    69421 tggcacttgc tcccatgtga atggttggga tttcttctat cccttgtctt ttgtaggaac
    69481 gatgatctac tctcttttcc tgatgatttt tttctaaata ctgattacaa agggttgcaa
    69541 aattctttct ccatttctct gcgttgcctt tatcgttcca gtctgtcagc tctacttttc
    69601 ttgttttgta attaccactt tttagtttta tcttttctcc cttttcatca agaacatatt
    69661 cttttttgct ttttgccagc cactctcctt ttttattaat cggtctaaga gtagtcataa
    69721 tatgtgcatg gatattgtta ttttcttcat catttccatc atgaatagca aggtctgcta
    69781 tcattccttt tgatacaaaa tgttcttgta tgaagtcggt aatgagtttc ttgttttctt
    69841 caaaggataa ttcttttggt agagcaatga taaaatttct tgcaagctgt gcattgcttg
    69901 ctttctcatt tagttcaacg ctgttccata atgtagttct atcttttaat gctatgggaa
    69961 cattctccgg caagaagatt tctgaatgta aaagtccctt tttattatgg taatcgtgaa
    70021 cttctccgtc ccattcattt ttgattttct cacaagagat atatgctgca cttgcaactg
    70081 ccgatttact ttttcctctg cttatcatag aaatattaaa gtgaaatgtt tctgccactt
    70141 ttaagctcct ttcatttttt gtttgttttc aggtaaagga aaaagcagac aggttatttt
    70201 ttgtatcttt tcctatctac tttatccgta tgtttttatt aagttttgga tttttaaaga
    70261 cttgctaaaa tcccttagtt tttctaaggg cgcaattata caccctaaag ggtgctttgc
    70321 gttctgcgaa gctttttgcc cttgcaggga gcttctgaaa aaactatggt tttttatttt
    70381 atctactcta tctctgtttc atcttccata tctttcccat ttatcatttc ttcataggct
    70441 tgtctgtatt cttttgtgtg agtagcaact ttaagtaatt cttctatctc atcgttagta
    70501 aacatgatag gatttttaat gactctttct actatcaagc ctctttgtat gagcctatga
    70561 tttcttcttt ttcgttcctt ttcgtttgca agtttttcta atttcttgcc ttgattttgt
    70621 aattgtttca gcttcacatc gcacttttct ctttcttgct gaagttcaga aatttgttcc
    70681 tgtacttcct gtaatgtgtt ttctttcttc atttttcatt cctccgtttt ggtatctgct
    70741 tgtttccata aagaaaggtt aagcaccttt ttttgacact taacctttcc aagtttttag
    70801 attttatctt ctaaaatctt tctcagtttt tctaaaatcc tatccctcct cccactgatt
    70861 gcttgatgtg taactttctc tcttctgctg attgacctta gactttcttc tttgtagaag
    70921 atggcttcca tcaactctcg ttcttctttt gaaagagtat ttaatgctct atgaagttct
    70981 tcaattcgca tttttacttc tacaattttt tctaagtcta tcttttcatc tatgatgtta
    71041 tctacaaagt gtccatcatg atccagtgcc gaaaatggta ttacattatg cttccaatct
    71101 tttctttgga gatacttttc atgctctgtt atcttccaat aggctttgta tacttcttca
    71161 cttacaggta cggctttgcc ttttacataa aggtaatatt ctttcttatc catcgtgtta
    71221 tcctcctttt cctgttctct aatttgtttt tgagaataaa aaaggaggac ttctacactt
    71281 tggcgtaaaa agtcctctcg gcttaaaaac taatgttgta tataattttc tatttggtcg
    71341 tttctggtaa agtattattg ctatgtgtaa gcaattccaa gaataaaaaa ggataattat
    71401 atcgttctgt gaaaaccgaa actataagtt ttgacataat tatccctcca ttattttccc
    71461 tcctaagtaa atttattatt aaatcactcc tgctttttca aaatgctttt tgagtatctt
    71521 tgttgcaacg aatgctccta tgcaagcaag aacaaaagtt atcaagccaa atcctactgc
    71581 ccacgaaact ttgaaataag ataatgcttc atttatttgt gcttcgctca ttttccattt
    71641 tgatgctctt tccacaaaag aagctgtccc gaataaaatc acaggaatta ctgtccctaa
    71701 aaaatctgct aatgcaaatg tcccatatcc aataatcatt cgtcccttgc tctcataatt
    71761 tcctataatc aaatcacata taattccacc gattacagca aagactgcat gaggcaaatg
    71821 tcctcctgac aatgcaatta aaccaagaag cgttcctgat attgtaaata cgcccttctt
    71881 tttaactttc aaagccataa ggatataaac tgtagcagct accataaagc taactcctga
    71941 cgcaataaat cctccaatca ctgttgttgc catagcaaat gcaaccgcca tgtatatgac
    72001 aattccaatt gcattaaaga ttccgattgt aataaaatca cgaccattta atttgttttt
    72061 cataaaagtc ctcctaataa attttctgta ttactatcac aagagcaatc atcaaagctc
    72121 ctaatagtcc aatcaacaaa tccgcccatc taaacctcaa ttttgttaat gtaaccctgt
    72181 tcgcatcact atcaagtcct ctaatgagtg ctgaagctga cagttcatct gaaatcttaa
    72241 tcattctcat taaaagcgga acaagcgtat attcaatata tttaattgga tgtagcaacg
    72301 ggaaaaatct acttgttacg attcctcgaa tcttcatatt ctcttttaat gccttgagtt
    72361 ctatttttat agttggtaca aacctaagca aaacactaaa aggtatacca atgcttcttg
    72421 gtactttcat tctatttaat gcttcaagca tttcacttac acttgtagtc tttgttatat
    72481 atccaccaaa catagcaatt aaggtcatcc ttgatgcaaa gtaaataaac atatatattg
    72541 caaatacgat acttgcttca cgaaactttc caagccctaa ctctatgcag tataaaagca
    72601 caaaaaacaa aataaagcgt aatgctcttt tccacatact actgtataca tacagaaaaa
    72661 aggcaaagac aatcagtccg aaaagtagga ttgtatcgct tataaaaaag ctggtaaagg
    72721 aggcaattgg aagtagaata agttttattc tcggatcgac tgtttttcta tctatcaagt
    72781 tctctacctc ctctcatctt gtctaatatg agaaatttat tactttcact catattcaga
    72841 accttttcta tttttccatc tcccattacc catagctcac tcactgtgtt tgctaaaaac
    72901 tcaaaatcat gacttatcac caaaactgtt gtcccatttt ttaattgttc ttcaatcaat
    72961 tttgcgactg aaagcattga gtctttatca caacctgatg ttggttcatc atagataaaa
    73021 acttttgcct gtttcatcat tccacaagct attgtcagtc tttgtttttc tcctcttgat
    73081 aaagcaaacg gatgcttgtc tatatattta tctaagccaa gtacattcaa aataaacttt
    73141 gccttttggg tattttcttt tttattttta cttgaaatac caagtagcat ttcatcaagt
    73201 acactttccg aaaacaactg atagtctgaa tcttgaaaga caaaatatga catatccatt
    73261 aaatctttgt gattaagcga cttatctttt cccgcccata ttgtcccctc ttttatcttc
    73321 tcaagtcctg aaagcactct tgcaaaggta gttttcccag taccatttaa gccgataaga
    73381 ccaatggctt ttccgcactc catattgaaa tcaagatgat ttaaaatgta ctgtttttgc
    73441 ttctttccat tcttagctac attcgaatag caaaatctca agccttttcc gctgatactt
    73501 tcatccttta attgatatga atctttcttc tcacttatcc tgtattcttc taattcaaga
    73561 gttcttaatc cattctcatc ccaaaactcc tcttcaagat gaataacttc ttcccgactc
    73621 aagtccagtg caatttctcc atctttcacc aaaagaaaac ggtcaaataa agattttaca
    73681 tagtacaaac gatgttcaat tagaacaact gttgttcctt ttttctttaa tttttccaaa
    73741 attaaaaaca ggtcaaatgt tgctttcata tccaaatttg ctgaaggctc atctaaaatt
    73801 aaaactttcg gattcattgc atagatgctt gcaatagcta tcttttgttt ctgcccgctt
    73861 gataattcaa aaacagattt tccttccagt tcctcaatat ccagttctgc atatacttct
    73921 gctactctct gttttatttc atctcttgat ttgcagatgg tttgaagccc aaaagctatt
    73981 tcttcatctg tcgttgtcgt aaaaaactga cttcttggat cttgaaatac agtccctaca
    74041 atatgcccta tttcatgaag cgataacttg cttatatctt ttccggacgc aaaggcttcc
    74101 ccttgcattt tgcctttgta ataatgtgga ataagaccat tcattacact tccaagagtg
    74161 cttttaccac ttccactttt ccctgaaatt aaaacaaatt cacctttttt aatttcaaga
    74221 ttgacatttt ttaaagcagt tcgtccatct tcccattcat aagaaacatc ttttagcaaa
    74281 atcatggtta taccccatac tgagctttcc ataattttgt gtagtaacca tttttcgcaa
    74341 gaagttcacc atgctttcct ttttcaagta aatttccttt ttgaaatacg agaatttggt
    74401 cagctttttg aattgttttt aaatgatgag ccactacaag tacagttcta ttctttgcaa
    74461 gttctgtaat agcatcctgt atcaaagatt catttacagg atcaacatta cttgtcattt
    74521 catcaagaat taaaatcggt gcatctttta gaaaagctct tgcaatagat attctttgtc
    74581 tttgtccacc tgataaaatt cctccatttt cgccaatatc agtttcataa ccttttggta
    74641 aactcataat gaaatcatgt attcttgctt tctttgcagc ttcaatgatt tcctcttttg
    74701 tagctccttt tttacctact ctgatatttt cttcaatcgt gttatcaaac aattgaacat
    74761 tctgcatgac aatgctaata cggtctaaaa gctcatcata aggaatatcc cttatatcaa
    74821 ttcctccgag tgtaattttt cctttatgca catcataaaa tcttagaagt aagttggtta
    74881 tagtggtctt tccactacct gattctccaa ctaaggctgt cattgttttt tcagcaatag
    74941 aaaagctcaa tttttccatt ttaaattcat ctttttcata ggaaaatcca atgttatcaa
    75001 aagctatatc attatctttc ggaacaattc cattcacttt atccgggatt acatctgcat
    75061 ataaaattct tgaaagtctt tcgtaactat ctaccgccga aacatagttc atatagtgtt
    75121 gttccataga agcgaacggc ttataaaact cttttgaaat tactgcaaag ataataaaat
    75181 taagtacatc aagacttccc tttataacaa gtattgctcc tgcaattaaa agaactaaat
    75241 atccaatatc cagtaaaaac ccaaatatag atagctgttt tgccttgaat cttgaagcta
    75301 ctttgcttgt ttctccaaac ttttttgtct tgttcataag ctcattatcc aagcttttat
    75361 tgtttgaaaa actctttagt acaggtattc ctctaacata ttcaacaaat aagctaacca
    75421 tatcaagaag tgctgaatta ttctgattct ctattctttc agattgctta attgtcagat
    75481 atagaaagac aagtgcaatc ggaacagata cagccattag aatagcaagt ttgaaatcaa
    75541 tacttgcaag accgataaat acgactgcac ctatcaaaaa atcgccaaac attctcgacc
    75601 acatgtgtcc tacaacaaga gacatattat caacatcttt gtgtaaaatt gtattgatct
    75661 ctcccagtct ttcattggta taaaatccca aactgaattt tttcaattta ataatcatgc
    75721 gttctctgat ttgctgaaca atatcaaaac ctgcactatg ctttttcata tctgcaacca
    75781 tattacaaat gcctttgaat actacaagta acccaattgc aataaaacct ttatataaac
    75841 ttgctaaact cgtcccatca aatatctgaa acagtataga aaatacgata acaatcatgg
    75901 ctatggagct tagtccataa agggcaaaga atacacttga tataatcaaa tctctcttgc
    75961 cggtttttgt aagcagcttt aacatttctc taaacatttt ctgttaccac ctctttcaaa
    76021 ttccatctat ctaccttgtt ctgtgcttca accatatcct tatagaactc acatcttttc
    76081 atcaactctt catggcttcc tgcatcaaga acaacaccct tatccataac tataatttgg
    76141 tctgaatctc taattgtgtt tagatgatga gcaattgtaa taatggtttt atccttgctt
    76201 aaatcgtcaa ttgcttcgcc gattagtctt tcattttcac tatcaacagc tgccattgct
    76261 tcatctaata ttaaaatcgg tgcatttttc agtatcattc ttgctatgga gattctttgt
    76321 ttttctccac cagataactt aactcccatt tcacctactc gtgtttcata tccatttggc
    76381 aatgctgaaa taaaatcatg gcatcttgct tttttagcag cttctatgac ttcttctttt
    76441 gttgcattta gttttccaat tgctatattt tcaaaaatac ttaaatcaaa aaggataatt
    76501 tcttgttgca cactaccaat cagcattgag atattttctt gactatattc ttttatatct
    76561 tttccattta tcagtatttg tccttcatct gcatcccaaa atcccataag caaattagat
    76621 acagtacttt tcccacaacc acttgctcct acaaaggcgt tcaaactatt tttcttaaaa
    76681 ttcaaattga tatttttaag ctcaaagcta tcttttccgt atgcaaaatt cacatcttta
    76741 aattctatat ttccaaattc taaaccttgt tctgtctttt tctttggaag cggaactgtt
    76801 aaaacttttc caatcgcctt tagtgcttcc ttaaacacaa tagaaaaatg ttgcaatgta
    76861 gccgtcttac ttatagatgc agtaaaagca gacgataaaa taatggcaag tataaaatta
    76921 ggggttgtaa tatttccata gtaaagaaat atacttccca aaatcatgac aataactact
    76981 ccaatttcca taaatatgtc aatgagtccc attggaattg taattgctcc catgctcttt
    77041 ttaacccagt aaatatattt tcttgccgtt tttaatgttc tttcactaat ctcctcttct
    77101 ttagcaaaag ccttaatcac agaaatattt tttacatatt ccattagctc ttctctcatc
    77161 ttattttcat ggttaaagta aatagcaaag tttttatcca ttgttttctg tgaaagaact
    77221 tttaccaaat acatgagtgg aactccagca atcattccaa gagcaagacg ccaatcaaca
    77281 aaaatcatag ctacaaaaat aatggtaggc agaagtgtaa ctgccattat ttcaggaaga
    77341 ccatgggcaa ggtatacttc cacttgctct acatcatgtt gaacaatgtt ggtaagctct
    77401 cctgtattat gttctttaaa gaatcccaaa cttagttttt tcagatgacc gataatatct
    77461 aacctaagtt ctgttaattt ttcgtatgct ttctcatggg caacctttgt tgcaaaataa
    77521 taaaacactc cttttaatac aaacgatata aagattccca agaatatata ctttaaatta
    77581 ccttcgttaa tattgtttgt gattaaagaa ctaatcaaat atacaagtaa gatttgtggt
    77641 atcaaatcaa atactatttt taaagcaaga agtgaattgg ataaactatt tttcccaatc
    77701 acttttttcc ttaattcttt ttccggcatg aacaactctc ctttcaaaat tgaataatat
    77761 tgaattttaa ttcagtatta aggtttaaag taagactttg ctgattacgc aaagtctatt
    77821 ttatccgatc actatatttt tttaaattac tgtatcagca aatcaaaaat tatagcacaa
    77881 tctttttcca ttttctaatc ttagttctaa acgttccaaa aggggcaacc gtattaacat
    77941 gaataaactt ataaacttcc catgtcgctg ttttagtagc ttcatcagcc cattttctca
    78001 tatgcggttg aaataattct tcttcactta gtgtatcaat cattgtatag atagatataa
    78061 tattttcttt caatcgtttc tttaattctt ctatcgataa atgagcataa gtatcggtaa
    78121 accactgata taattctcca agttgattcc atttaaacat atccgacggt gtctttactt
    78181 caaaaccgtt tttctcatct ttttcccatt tcaaaactaa tgttgtccat ccgagttgat
    78241 aagcaagatt ttctgctggt gttctgtcaa cttcagggac tctcttatct ttgagagatt
    78301 caggaataat atcaaattca gaaatatact tttcaaaact tttatttatc tcagatttca
    78361 gttcttcttt atctttatat atcttcaaaa tatctcctcc aaaaatttaa atttatcgca
    78421 tttaaatatc aaatcaactt acaatgattc cactcccttg taataacact ttgcaataag
    78481 ttttagcata tcttttgccc acttttcact ttgataatgc cttgctattt caagaagtcc
    78541 ctctgtaaag ttactggcta aaatatgggc aagcattgga tcatattcct gtttcgattg
    78601 tctttttaaa cttacttcaa tatgaacctg catttgcgat atgagttttt gttttgcttc
    78661 tgtatgcttt gtacctgagc ttttatccat taaaataatt aacttcttac gatcttttaa
    78721 aagttcatga atataatttt ctccaacttc atcaaacctt tcagaagcag aacctttttc
    78781 caaagattct tcctcattaa aagctgactc gaagtttata taaacagaac ttactactgc
    78841 atcaaacaaa actgccttat ttttgaaata ggtataaatt agtgccacag gaatatctgc
    78901 ttcttttgca atttctgtta atttggcacc tctataatcc tttttataaa atactttttc
    78961 tgctgcttcg agtattctat ttctaacttc ttcttttaat acttgtgcca tagcacacct
    79021 ctttctattc caatactgaa tctatattta ataataaatt aaaattcaat atttgtcaag
    79081 atagatttaa atatttgttt ttatatactc actcaccggt atccccactc ttttcaaaac
    79141 ctttattttc tcctgtttct tctgttctct tcttgcctta tatttatctt catactcttt
    79201 ctgttttcca ctcgctttac gctttaggta attttgatgt agcttatctt ttctttcttc
    79261 gatttttctt tcttcttcct caagtttttg ttttttttct tcgcttaact ccgcctgtgg
    79321 tagttcgtaa ttacctatga aattaaagta aatttctatc ttttgctttg atgtctgact
    79381 tccttttcta tctctttcat gtacgataat cttttctaca aactcattta tcattgtagt
    79441 tgtaagttca tcaaagtttt cataacgact gataagagat ataaattttc ttgctctgtc
    79501 tgtttctttt tcatatcttg atacctgctg ctctaaatct ttgatctctt tgcttaaagt
    79561 tatctgctct gtttcatatt gattgtttag tatctcatat ctgctatttg gtattttgtt
    79621 aaggatcata tcttcgtaaa ttctgcacat aagtcgttcg agttccctaa gtctgttttg
    79681 gctttccgtt aatcttacct ttttcttttc tatctctatt ttttcttttt cttccatttc
    79741 attttgaatg gaacagataa aggcttcatt atcttcatca aggtattttt taatatcttt
    79801 tagtgtgtct tgtattaaat ttaagactac ttccgctttt attctgtgtg ctgatggaca
    79861 aagcatgcca caaggtgttt tagtataggc actgcaagtg taatagggta tatttttgta
    79921 attgcttgtt ctatgaacat acattttact tccacaatct gcacaataca tcagtcctgt
    79981 gagtgggtga tattctcccc aaccgtcagg ataccttttt acatttcctc ttatcctttg
    80041 cacattgtca aaggtttctt gatctataat tggctcgtgt gtattttcaa aaataagcca
    80101 gttatcctcg gatacatatt tgcttttctt gtccttgaag tgttttcttg ttttgaaatt
    80161 gactgtatgt cccaagtatt cctgtttctt taaaatgctt gctatggttg agctgcacca
    80221 acgataggga tgttcaaagt ttttgctttg atatagtcca tagcctaatt tctgttgatg
    80281 ataggctggt atatctactt tttcactctc caatatcttt gctattcgat acggaccatt
    80341 tccttgcatg gtcaggttaa atattcgcct tactatctct gctgcttttt catctactat
    80401 ccacttgttt ttatcttttt catctttgat atagccataa ggcggtgtac ttgcagtatg
    80461 tttcccactt tcgccttttg acctgaaagt cgattggatt tttcttgatg tatctcttgc
    80521 ataccattcg ttcatgatat ttctaaaagg ggtaaaatca tcttctctgt aaaaactatc
    80581 tacattgtca ttgatagcga ttagtcttac gcccttttgt cttagtatct ccatacattg
    80641 accgactttg agataatctc tgccaagtct gctcatatct tttacaatga tacaaccaat
    80701 atttccttga ttgactccgt tcatcattgc cataaatccc ggtctgtcaa actgcgttcc
    80761 actgattcca tcatctgtaa agtgaatgat gtttgacaaa ttatttttgc ttgcgtattc
    80821 ttccaatatt tttttctgat tgatgataga gttactctct ccttgcagtt catcatcacg
    80881 acttaatctc tcatagagtg ctgttatctt ttcaaaattc ctcattttta ccccctttct
    80941 cttaattttt caataaaaaa agaattaaga agtacatatt tcactaaaat agtgattaag
    81001 tgttctcctt aattctatta ctcccgcagc caatttgtac tttttatatt gcttcactgc
    81061 aaagtgtgta ggttctttct tctccagtgc ttcaaagagc ctatctatcg gattcatata
    81121 ggtttcatta tcttctctga cttctgaagc atcaatcata tcaagcagag ttgcaaagtt
    81181 cttttcttct cttggagctt catagaagat atagccaata agtgctgtat agtagagttt
    81241 ctcagctttc acccaaaaat cttcacctga tttttctccc tctcccttgg tgtttgcgat
    81301 aattgtctgt actaatttga gtatgtcctt ttcacttcta agataagcaa agggattgta
    81361 tttcatagac tttttgaagt taatggtatt taggattttt atctcatatc cgttatcttc
    81421 aagcatctta ccgcactcaa ggactatagt tcctttagga tcggtcacac aatatgacga
    81481 gtgcatctgc ataaggttcg gttttacata aaatctcgtt tttccacttc ctgatccacc
    81541 gattacaagt acattcttat ttcttgcata ctttggattt gccggtctgc cattcatggt
    81601 taatcgttct gtttgcgtaa gtaggatatt gttttgaaac ttttcatcca tatatggctc
    81661 tatatctttt ttcgttcccc atcttgctga gccatactct ttcccctgtc taaacttttt
    81721 agcatttttc cctttggtat atacgataat tttgattaaa acagctacta ccactcccat
    81781 taaaatatcc gtaggatgaa tgcttggaag aaagctcatc gtgttaatct ctaatatccc
    81841 ttgaaagatt ttgtcaataa tatcgccacc tacatagact cttacatgat gtgaaaagat
    81901 attgcctaca tagaaaaatg caagataggg aatgttctgc tttagaaact ttaccttatc
    81961 ttgcacctta cataagcctt tgatatcctt taatatttta tctatcatag gctttgctcc
    82021 ttttgtttat ttttgatttt ctcttttgaa atagagtttt tagccatctc tttgaacttc
    82081 tcaatattct tgtgaataga ttctttcctt tctgctttct tttctgattt tgaaagaacg
    82141 tgcttaaaag ctttatccat cactttcata tctttggctt gaaagaatac agagttttta
    82201 cctgtctctt tatttttcat cactgaaaat ttaacaccgt atctattcaa ctctttttta
    82261 agttctttaa gctcagcttc ttccactggg atttcttcaa gctgtccctt tttaaccata
    82321 tcttttagct ttacttcatt tccgttgaca ttgaccagtt tttcaagtcc tccgaatttc
    82381 tctgcttctt tcatcaattt ttttaataag tttaatagac cttttccagt aactttacca
    82441 gcatttatct ccatatttaa ggtctttctt gctatttctt cattgatcac atcaatatcc
    82501 tcctctcata tcatagctta caagagccga ataataggca tctattccac ttggtgcatt
    82561 ataagcggcg gtcagtacaa aagctcttat atttctaatc ttatattcat tttctcttaa
    82621 tactcctact aagtactcta aatgtcctga attaagtttc ctaaatcttt cctttactac
    82681 ttgtacagat atctttgttt ggttgatagt aatgaaagat tcatcatcta ataccattac
    82741 atctgccagt atctttaata tttcatcaaa ctcttcagcc acactcttat tcccaatgct
    82801 catatgttca taatatcctg tttggtgtcg caattcttct aaacaatttt gatatatatt
    82861 tttatagctt atatctatcc tccctccctt catattctct gaaaataatt gattcttttc
    82921 tttgatggaa ggatggatgg aaatatatgc tgaattattt gttgtattat ttgttgtatt
    82981 ctctggtaat ggttggtgca aattatcctt ttgcattagt gcattttgaa cctgtgcatt
    83041 agtgcaatct gcattattgc attggttgat tttgccctta tccattggtg cattttgccc
    83101 taatgcattg ggcatagaat tttttaatgc ttctgtttgt attttttgtt tttttaaatc
    83161 catatccata tataattctt caagtttatc attattaatt gtataccatt ttgttttatc
    83221 tcttggatcc ttattgtaat ttccaactaa aagataacct gctttttcta actttgaaaa
    83281 agttcttttt actgtatcaa agctcatata gtcaaagtca ttttcttgcc atgctcgaat
    83341 tgaattatat gtccagtatt tcccattatg gtaattcttt cccgattttt tatttatttc
    83401 tatccaataa ttgatctgct gtagtacaag cgcttcgttt aatcctaatt ctcttgcaag
    83461 agttttattc gcgactatag gttgttcgtc aaataaatac ataccatcaa acactccttt
    83521 cttttttcaa ataaaaagac gatagttttt ctatcgcctt tgataaccca tttatgaaat
    83581 ttttaacttt actgtctgta atttataata ctattttctt ccattttcta attttgttcc
    83641 tgaaagtttt aaaaggagct acagtattca catgaataaa cttataaact tcccacactg
    83701 ctgttttagt cgcatcatca gcccattttc tcatatgtgg tttaaataat tcttcatcac
    83761 ttaatgaatc aatcattaca tatatagaat taatattttc atttaattta gattttaact
    83821 cttgcaatga taaataagca taagtatctg tgaaccattg atataattca ccaagttgat
    83881 tccatttgaa ttcatccgat ggtgtcttta cttgaagccc atttctttca tcttcttccc
    83941 atttaagaac taaagttgtc catcccacct gataggcaag attttctgcc ggcgttctgt
    84001 caacttcatc aattctttta tcttttaagc tttctggaat attatcaaat tctacaatac
    84061 acttctcaaa tgttttattt atttcagttt tgagttcttc tttattttcg tatactcgca
    84121 taaaattacc tccacaactt ctgatttatc aattctctga tttaaactga cattattttc
    84181 tcgtttatac cttgcaataa tgctataatt gacgctccaa ccatcggtat cccataagga
    84241 ctaagtaaaa atcctataat taaggcttct ataccaatgg taacctcttt ttgtaaaaaa
    84301 gatgctattg ctccaaatat acaaaaaatc atcagcaagt acagtattac tgttcctatg
    84361 ccaagtaaaa atgaaagaac tgcagtgagg atacttaaca acaagctaat tggaaataag
    84421 ataattttta atatccatct cataaatacc ctccatttct actaaatcat tttaaaatgt
    84481 cttaaagcat ccatgatagc ttcttctttt tcaggcgtac actgtaggat agcctgatta
    84541 tcttttttag atttattata atgttctctc atttcaatcc cacatttctt tttagtttgt
    84601 gcaatataaa gtgtagaaac ttttagtcca aatttttcta atacatactc cttgatttga
    84661 gcgtatgttg ctttactctc tgcacttgtc aaatcaagct catccagctt aatttcaaca
    84721 tctatatgct tatcgacatt aagtttggac aataacgcta ccgtctccac atgagtagaa
    84781 tgagggaaca tatctacagg ttgtgcctca acacatttaa atccgtgaac atttagataa
    84841 tctaaatctc ttgctaaagt agaaggatta caagaaacat agacaattct ttccggactc
    84901 attgaaacaa tagtctctaa taccttttcg tcacatccct ttctaggtgg gtctacaact
    84961 actacattag cagtcttacc ctctctatac atcttaggta caatttcctc tgccttccca
    85021 acataaaatt cagcattatg catattgttt aatttagcat ttatcttagc atcttttatg
    85081 gcatcatcta taatttctat tccataaacc tttttagcct tttgtgccaa aaataaagat
    85141 attgttccta tcccacagta aatatcaaaa acagtatcag tctcatttaa atctgcatat
    85201 tcaagagcct tatcatacaa tactttagtt tggacaggat ttacttggaa aaatgataat
    85261 ggcgaaatct caaacactaa gtcacctata taatcattta tttttccatc tccatatata
    85321 actatatttt cttttcctag aatggcattc gtatcttttt gatttacatt tacaaccaaa
    85381 gtcttaaatc caggtatatt ttccttaaga actgaagcta attctttaag ataaggaagt
    85441 ttgtttccat tcgctactaa tacaaccatt acttctttag ttgtaaaacc tattttggtt
    85501 actaaatgcc taatcaatcc tgtatgagtc ttttcatcat atatacttac cttataagct
    85561 cttatatatg tttttattat tttaacaatt ttatcattta tctcatgttg tattacacat
    85621 ttttctgtcg atattacatc atgagtcttt tttttataaa aaccaataat tggaacacca
    85681 ttattctttt gtattggaaa ttgtgcttta tttctatatc tatatggatt atccattcct
    85741 atagtgtcat gaacttctac atcttctaac ttacctattc tcgaaagtac ttgtttaact
    85801 tcatttgttt tcatttcaag ttgtttatta taatctaaat cttgtatctg acaccctcca
    85861 caatccctga gattgtcact acacactctt ttcaccctga atggagactt ttctattatc
    85921 tcaacaatat ctcctacagc ataatttttc tttactttat taatcctaac tttaactttg
    85981 tcctgtatta atccgccctc tacaaaaact gtaataccat tgtactttcc tactcctact
    86041 ccgccttgac caatgtctac tatatctaca atatacacct cgtttttcga aagcataaat
    86101 caccctccaa tcaatctatt atatttaaat ctttacaaac ttttttcttt aaatttatat
    86161 taaaatattg ctattaatta aactatattt tttactaagc tacaatattt tattttacca
    86221 aaaaaaaagg agcttataaa gccccttggt aaataaattt attatttttc ttataaaact
    86281 ctagttgaac ctctatatac cacacctctt gatgcgtcca cagttacaac ttctccatct
    86341 tttactagat ttgttatgtc agttgcagac acaataactg gtatatctaa atttatacct
    86401 acaatagctg tatgtgatgt cattccacca ttctctgtta ctacagctcc tgctttttct
    86461 atataattgt tcatttcagc atcagtagca gtagaaacaa gtatgtctcc ttcattaaag
    86521 tctacacaag tatctccatt ctttatcaca cgaactttac cttctactgt ttgagtacct
    86581 acacctatac cttgcacaat ttcttcgctt attacatgaa cctttattaa gttagtagtt
    86641 ccacttactc ctactggtac tccagcagtt ataactacta attctccatt atctatataa
    86701 tcagcttgtc tagctgcctc aattgccttt tctataactt catctgtatt tcctgcaaca
    86761 gaagacttaa ctggatatac tccccatgta agagctaatt tattcatagt tttttcatta
    86821 tttgtagtag ctattattgg agattttggt ctaaatttag ataccattct agcagtatat
    86881 cctgaagaag tagatgttat tatagctgat gcatttaaat ctactgctgt tgtacaagtt
    86941 gcatggctta ttgcatctgt tacagtaaca ttgttagtac cattttcctt taataatcta
    87001 tcataatcta aagtctcttc tgttcttttt gctattgtag ccatcatttt tactgcttct
    87061 acaggatatt ttccagcagc agtttctcca gataacatta tcgcatctgt tccatcatat
    87121 atagcattag caacgtctgt aacttctgct cttgttggtc ttggatttct tatcatagaa
    87181 tcaagcattt gagtggcagt gacaactggc tttgctaatt cattacattt ttttatcatc
    87241 attttttgaa ctattggcat ctcttcagtt ggtatctcaa cacctaagtc acctctagct
    87301 accattatac catcagaaac ttttaatatt tcatctagat tctctacacc ttcttggttt
    87361 tctattttag atattatttg tatatcagtc gcattattgt tctctaatac ttctcttatt
    87421 gctagtacat cagatgcctt tcttacaaaa gaagcagcta tataatctat tccttgactt
    87481 attccaaatt ctatatcgct tatatcttta ggagttattg ctggtaaatt tattttaaca
    87541 ccaggtacat ttactccttt atgattttta actattcctg aattttcaac aacacaaatt
    87601 atatcttctc catttatttc ttttactctt aagccaacta aaccatcatc tattagtata
    87661 gaatctcctg atttaacatc ttcagcaaga cctttatagc ttactgtaca catttcttta
    87721 gtccccataa tatctttcat agttatagtg aacttttgac cttcttctaa aaatacctct
    87781 gggtcttcaa agttacctgt tctaatttct ggaccttttg tatctaataa tatagcaact
    87841 ggcttattta atttttctct aactttcttt gccatatcta ttctttcttt atgttcttca
    87901 tgtgaaccat gagaaaagtt aaatctacac acatttagac cattttgcat aagttgagtt
    87961 aaaacttcct cactttgtga tgctggacct agtgtacaaa caatttttgt cttctttaca
    88021 ttatttaaca tatttgctcc tcctgagata ttattccaca gatttatttt taatactaaa
    88081 acttatatag ataatatttt tgccatctca taagcttctt tatcaaatac tttcttttga
    88141 gctaaagctt cacttatttc taagtcaatt attttgtttt cttttattcc tacgactcta
    88201 gctgattttc catctaataa taattctact gctcttactc caagtctact tgctagtatt
    88261 ctatcagata cagttgggct tcctcctctt tggacatgac ccaacacagt tactcttaaa
    88321 tctgctcctg actctttttt aagttccttt tctaaatcgc tggcacttcc aactccttct
    88381 gctaaaacga ttatactatg tctcttacct cttttttgag tagtctttaa tcttaaagca
    88441 acttcatcta ctgtaatttc tacttctggt actattatag tttccgctcc tcctgcaaga
    88501 cctgcatata atgctaaatc tccacagtgt cttcccataa cttctactat attaactctt
    88561 tcatgagacg atgatgtatc tcttatctta cctatagcat ctataatagt attcattgca
    88621 gtatcaaatc ctatagtata gtctgtatat gctaaatcgt tatctatagt tcctggtata
    88681 cctatagctg ggaatcctaa gtcactaagt ttttgagctc ctacgaatga accatctcca
    88741 ccaattacaa ctaagcaatc gattttgtac tttttaagaa tttttactgc ttttaatcta
    88801 ccttcttctg ttttaaattc ttcacatcta gaagatttta atattgttcc tcccctgtgt
    88861 ataatatctc caacagaaga taggttcatt tcagttaaat cttcttctag taatccctta
    88921 taccctctat tgattccata tactttgcat ccataatata ttgctgatct tacaaccgct
    88981 ctaatcgcag cattcattcc tggagcatct cctccacttg ttagtaatcc tatagttttc
    89041 attttttacc tccttggatt ttatgtcaat tttttattat aatcattgtt attgtattct
    89101 aatggacttt ttttgtccct atatcacttt ttaatcccat caagactaaa aaaattaaat
    89161 gtccttaaat gtccattttg tgatattata tcacaaaacg gacaatattt ttcatattat
    89221 tataatatat ttagattttt atataaaaaa tcaagctttt acttttatgt tatctttagg
    89281 aagtaactct tctaagttat ttataaattc atcacatata caagttaatg cccctgtcat
    89341 tttatatgct ttacgtttgc catttatatt ttcatccata gggtacaaat atatactgtc
    89401 attacccgga tattgttttg ctatttctac aatattatta gttgtatcgg tgtcagacat
    89461 actatctatt ttcaaataca attttttacc actttctggc ttaatatttt ccacatttct
    89521 agttcttcct gaattgtaat ttctatctac aaagtcagta tcatcattta tatcttttat
    89581 ctctctagct ataagttttg cattttcgcc ttcttttata cttaatgttc cttttacata
    89641 tattatatta tcttcattca aaatgacatt gtacttttgt aataattgag gaaaaactac
    89701 tatttctata gcaccataca aatcttctaa ttcaagaaat gccataattt catttcgttt
    89761 tgttgtttta atagttttag ttacaatcat tccacccatt ataacatctg tttcattcat
    89821 ttgcaggtat gactcttctt cctcttttaa tgaatttaat tttccattat ccatagatgt
    89881 tttttcttgt aattcttttt caaattgtga caaaggatgt ccacttacat acattcccaa
    89941 gacttctttt tcaaggttaa gtctctctct ctcttcgtac tcttgccttt taggcaaact
    90001 atatatttgt tgaaaatcac tatcttcctc actatctcca aaagcatcaa ataaagaaat
    90061 ttgaccttga acatttttct ttctatccat agatacactt tctaataaac tttcataacc
    90121 agccatcaaa ctagctctat tttcacttat attatcaaaa gctccacatt ttattagact
    90181 ttctattact ctcttatttg tatctttttg gtctaatctt ttaactaaat ctactaaatc
    90241 tacaaataat ccattagatt ctctttcagc aattatattg tttattatat ttacgccaac
    90301 attttttaca gctgctagac caaatcttat attgtcacct tcaactgaaa actttgaaaa
    90361 acttttgttt atatctggag gtaatacatc tatttctagt gctttacatt ctcttatata
    90421 ctcaactacc ttatcagtat ttcccattac actggttatc aatgctgcca taaattcaac
    90481 tggataatat gtctttagat aagctgtctc ataggctaaa accccatatg cagctgcatg
    90541 tgatttatta aatgcatatc gagcaaagtc tatcatgtca tcaaatattt tattggctat
    90601 ttcctcttct acaccatttc tgatacaccc tgcaatttct atattaccat cttcatcaaa
    90661 tttcccatga ataaaatatt gtctttcttc ttccatcaca tccatctttt tcttactcat
    90721 ggctcttcta actaagtcac ttcgtccgta actataacca cctaaatctc taacaacctg
    90781 cataacctgc tcttgataca ccaaacaacc atatgtaact tccattatag gctttaattt
    90841 ttcatgtagg tatgttacat cttttggatt gcttttattt tttatatatg caggtataga
    90901 atccattgga cctggtctaa atagggatat tcccgctaca atatcttcaa aattgtctgg
    90961 ttttagctgt ttcataaaac ttctcatccc agcactctcc aattgaaaca cccctaatgt
    91021 attcccagat gaaagcattt catatacttt cgggtcgtca tagtccatct ttgaaaaatc
    91081 tattttttct gtgtagtttt ttataactct atttttttct attaaatcaa gagtatctct
    91141 tataactgta agagttcgta gcccaagaaa atccatcttt aaaagcccaa gttcttcaag
    91201 tgttgtcata gtaaactgtg ttgtgattgc atcttgatgc ttgtataaag gtacatactc
    91261 atctacagga ttttttgata taacaactcc tgctgcatga gtagaagcat gtcttaacat
    91321 accctctatc tgttttgata tatttattat ttcttttgtt tctgggtctt ggtcatacaa
    91381 ttctttaaga ttaggatttg tatctaaagc cttatctatt gtcattccta aagcaaatgg
    91441 tatttccttt gctatcttgt caactttatt gtaacctata tccaatactc tcccaacatc
    91501 tcttattgca gcttttgcac ccattgttcc aaaagttatt atttgagcta catggtcatc
    91561 accatatttt ctctttacat aatctataac ttcttctctt ctctcataac aaaaatctat
    91621 atctatgtcc ggcattgata tacgttctgg atttaaaaaa cgctcaaata atagagaata
    91681 ttttattggg tctatgtcag ttatcttaag tgtatatgct actattgaac cagccgcact
    91741 acctctacct ggccctacta tgatattatt ttctttagaa aaatttataa aatcccaaac
    91801 aattaaaaaa tactctacat aacccatttt ttcaattaca tctaattcat aatttaatct
    91861 ctctagtatc tcatcactag gattatcata cctctctttt aatccattaa aacacaactc
    91921 tcttaaatag gtttctggtg tatacccttc tggaacatca tacttaggaa gatgtatagt
    91981 gttaaaatca aactccacat tacacatatc agctattttc acagtattgt caatagcctc
    92041 taatgcatat ggaaataatt cttccatttc ttctctcgat tttaaataaa actcatcact
    92101 accaaatctc attctatttg ggtcatttaa tgtttttccc atttgaatac acataagaac
    92161 atcatgtatt ttcgaatctt ctttatttac atagtgaaca tcattagtag caactagtgg
    92221 tataccagtc tcttttgata gttttactaa tccagagttt acttcttttt gctcaggtaa
    92281 attgtgatct tgaatctcca aaaagaaatt ttcttctcca aatatatctc tgtagtcaaa
    92341 agcaaattgt tttgcttttt cataatttct attcattaaa gcacgtgcta catctcctgc
    92401 aaggcatgca gaaagtgcta taatcccttt gttatgtttt ttaagttctt ccatgtcaac
    92461 tctaggctta tagtaaaaac cttctacgta tgaagttgaa actattttta ttaaattttt
    92521 atatccttcc atattcttag ctaacagaac taaatgtcct tgatatttat catagtttgg
    92581 gtctttatct ctaagtccac gtgcagctgt atagacttcg caccctataa tcggctttat
    92641 tccttctttt atagccgttt tgtagaaatc tataacacca aacatacaac catggtcagt
    92701 tatagctatt gagctcatgt ttagttcctt agcccttttt ataagttttt tcaccctcga
    92761 aaacccatca agtaaactat actcagtatg tacatgaaga tgagcaaaat ctttgttcat
    92821 taaatcacct cctgctttat aattttacca caaatatatg tcctaaaaca aaaacagaga
    92881 cttttatctc aaaataggaa ttaacttcaa catataccat tatatgttat aaattaatgc
    92941 ttattctgag attgtcccct caatttattg tgatgatttt tttttcaaat ctgtcgcaat
    93001 ttcttctatt tttctaagcc tatgattgac tccagatttt cctattggtg gttctaacat
    93061 ctctccaagt tctttgagag tcatatcctc atactcgatt ctaatcttag ctatttcttg
    93121 taaattttct ggcaaactgc taattcctat agtttcttgt atgagcttaa tattttctac
    93181 ttgtcttact gctgcattta ctgttttaga aaggttagct gtctcacaat ttactatcct
    93241 gtttacatta tttctcattt cttttactat tttagtattt tgaagactta aaagagcatg
    93301 gtgtcctcct ataatactca acaaatctga tatttgctca ctctctttga tataaacaac
    93361 gtgattattt tttctagcca caattttact attaaatcct aaagagttta taagttcttt
    93421 tagagaatct gcaaactcct cattattagt tacaaattcc atatgatagt tcttttctgg
    93481 gtcgcttata gaacctccac caagaaaagc tcctcttatg aaagctctct tacatccttc
    93541 atgcttaatt aagttatctg aaattttgtt tatagtaaaa aatccttctt tattttcaag
    93601 tatacctaac ttttttaaca acatttctga acccatttca cttgttacca ttaatacata
    93661 actgttattt ctctttagca tttgattctt atttaccgag attgtagtat tgatattaaa
    93721 attcttcttt aataatttaa atactttacg ggctattgaa tttaactctg ttgttatctt
    93781 tagatttaac ttcttatatc caacaatttg tatacttccc cctgatttaa ctagagctga
    93841 caattcagct atattacaac attcattccc agatacaact ctcgctagtt catttttggt
    93901 ttcagttgaa aaagacatat ctatcaccta ttaactaatt tttctttaac ctttttttta
    93961 tttcttgtaa ggcaaccttt attatctcct tttcatcatc atacctagct aggtctacta
    94021 ctctatctag atggataaat ttagcatcaa taaagccttc ctctttttgt ggaatagtat
    94081 ccatattctt tgcttgcatc aaataccaaa aaactgtttt atgaactgct ctattttcat
    94141 cccagttttc tttgaatgta tagtgtattt cacctaaata tttcaatata tctgctttta
    94201 ctccagtttc ttcactcact tcacgtaatg ctgcctcttg gttattttcc ccttcttcta
    94261 cttttccctt gggtaacacc caatctccat tgaacttcct tagtaaaaga attgtattgc
    94321 caaacaggac tacaccacca gcactaacct cttctctcat cgatgttcac tccttaaaac
    94381 taacataatg ataaggattt ctacacaatt ttttaaaatc cttttttact aacttttgtt
    94441 gtaattatga tttagggcta actcaataac tatgttagat atatactttg catcatgtct
    94501 tatataatta ttttttattt caattaaatt cttctctaca gtttttatac ccatctcttt
    94561 taatttatct ttttgctttt tatctaacaa aacttgttct gctccatctt gtttgtataa
    94621 gtcaagcatt tcttctggca gtatctcatt atttgcgatt acataatcta ttaaattctt
    94681 atcagtatgc tttactatag cattaacatg ctctaataca ttgtaccctt ctgtctcacc
    94741 gggttgagtc attatatttg ctatatatac ttttggagct acagacgatt taatagcgtc
    94801 tacaatcccc tctacaagta aatttggtat tatactcgta tataagcttc cagggcccat
    94861 aattataatg tcagcatcgt aaatagatgc aataacatcc tttaatggtt tcacatcttt
    94921 tggatttaaa aaaattttat caatagagct tttttgaatt tttgactctt caggtatact
    94981 agattctcca tttattatat tgccattttc taatttggca actaaattta catcttccaa
    95041 ggttactggc aaaactcttc ctgttatagc aaaaatctca cttaatttat atacagcttt
    95101 ttcaaagttt ccatacaacc cattcatagc agccaaaaac aaatttccaa aactctgacc
    95161 ttttaaaagc ccttctgtaa acctatattg cataacttca ttcattgttg gctctatatt
    95221 tgcaagtgct aatagacagt ttcttatgtc tcctggtggg agcattccta agtcttctct
    95281 caatacacct gaacctccac catcatcagc aacagttaca attgcagtta tattttgcgt
    95341 tgtgtgttta aggcctctta aaaatactga ttgcccagta cctccaccta ttacaaccac
    95401 atttggttct ctattttcaa caatagacct ttgaaataat tttacttttt cattttttgc
    95461 ttttttatat ataaataacg atataattaa tgcaatccaa cctaaaattc ctacaataat
    95521 aagtaattta gccatgtttg cctccattat cgcaacatag agtctctatg tttctttaca
    95581 actctatatc ccttattaga taaatcctcc gctataagat ttgttatagt aactgaccta
    95641 tgtcttccac ctgtacatcc aacaccaatt actagatgtt gttttccttc ctctatatat
    95701 tgaggtacta aaaaatgaat catatctaaa agtttcacat aaaattcttc actgatttta
    95761 gaattcataa cataatctct aacttcttta tcatcaccag ttttagctct taactcttca
    95821 acataatagg gatttggaag aaatcttaca tcaaatacta aatctgcatc agcaagtata
    95881 ccatgtttaa atccaaaaga tactacagaa atagttaggt ttggattatc ttcaccagaa
    95941 gaatatattt tctttatttc ttccttaagg tctttgggct tcatgttagt tgtatcaatt
    96001 atacatgtag ataattcctt taaaggttcc attatctttc tttccatttt tataccttct
    96061 ggaatctgca tatcttttgc caatggatga tttcttcttg tcattttata tctctttaac
    96121 aatacatcat cattacaatc caaatatacc atttcatatt cataattttc tttttctaaa
    96181 taatttaagc tttcatgaag cgcttcaaaa aactttctcc ctcttatatc tatccctaga
    96241 gcaaccttat caatacttga atttggttga taacataatt ctgcaaattt agttatcaaa
    96301 gcaggaggta gattatctac acaataaaat cccatatcct ctaaagctct cattgtctca
    96361 ctttttccag atcctgaaag acctgtaact ataacaaatt tcattgctaa ctcctccctt
    96421 ttatcttatg tttattatat tataatgttt tctactaacg atatatccag attagagtca
    96481 gatatagtct ttatagctag ttcaaaatcg ccaactcttt ctggacaatg tgcatctgag
    96541 cctattataa atttattttc tagccctttt atctcattta attgatttaa gttcaaaaaa
    96601 gaatggctac tgtttatttc aagtctagtg tcagtctttt ttgctgtctt tgctatttcc
    96661 tctatataca catcgccttt atctcctgga tgagtaatta taaaaatatc attattactt
    96721 atcgcatttg ctacagcttt tgtattatat tcttttgctt tttcagtttt aaaaatatag
    96781 ttattacaat gatttaataa acttcttaat gatgttggag tagaaccaaa atgatatcca
    96841 gccataatat agtcaaaata tctaatgaac ttatcatcca tatctatatt gcctttatcg
    96901 tctaatatgt tacactccat acctaaaagt atatttatat cattgtactt atcatttaaa
    96961 taatctactt cttctctcat tttaagaata tcttttttct ttacaccata tgcaatatgt
    97021 ttataactat ggtcagatat tcctattgtt tttattcctt tagaaatggc cacctttaca
    97081 ttatcctcaa tagtcccttt gccatgacta tataatgtat gtgtatgata atcagccagt
    97141 attttcattt gttaatcctc tccaagtatt ttgacttctt cttccaacat aaccccaaac
    97201 ttggcatata cagcactttt tataacatat attaaatcca aaatatcttt agcacttgct
    97261 tctccttgat ttactacaaa tccacaatgc ttctcagaca cttgtgctcc tcttaaagta
    97321 agacctctca atccagtttc ttctattaat ttacctgcaa aatatcctgt tggtctctta
    97381 aatgtacttc ctgcactagc aaaatttaat ggctgtttag ttattcttct cgtcgctaaa
    97441 tcatccatta aactttttat ttcatcataa ttgccttctt gtaattctaa ttctgctgat
    97501 aaagctatat atccattttt cgatattata ctttttctat acccaaattc catctgttta
    97561 tttgacaatt caaatatatt gccttccata tccatcactc ttactgactt tactatgtcc
    97621 ttcatttcac caccatatgc tccagcattc atggctaatg ctcctcccaa tgtcccaggt
    97681 attcctgatg caaactcaaa cccttttaat tcttgctttt ggagagcttt acctaaaact
    97741 gataataaag ctcctgactg agcagtcatc ctagtatcat ttatctcata agagttaaaa
    97801 ttatcagcta attctattac cactcctctt attccaccat ctttaattaa aatgtttgaa
    97861 ccatttccaa ttattaaata cggaatagat tcttttttta ccaacttaag tacatttttt
    97921 aattgttctt ctgttctagg tctaactaat atatctgctg gtcctcctac cctaaatgaa
    97981 atatgttttt tcataggttc atcgactttt atatcctctt tacttaatat atttaataaa
    98041 tttatatata tatcttgatt attcattgta tttcctccca aattatactg aactttagct
    98101 gtcattatta tttaaattat attagtatat agtattaact atattcaata atatatgatt
    98161 ttgcttatca tatggatttt atattttaag cttcttaatt acaaactata ttcaataaat
    98221 atataataaa gtaaaaaaaa aaaaataaca acatataaaa gaatataaat aatttaaaaa
    98281 aagcatcaat atcactgata tcaatgcttt aaaaggcaat ttaattcata ttatttatct
    98341 aactattttt gacatagcaa agataataaa tccctccaac taccatggaa cctccaacga
    98401 tatttccaag cgttacaaat accaaattag ttatgaattg aaccatagtt atatttgctc
    98461 ctagtgccat tcccattggt ataaaaaaca tgtttgcaac actatgttgg aatccacata
    98521 atacaaatag cattattact gtccaacatg aagccaattt tgacattata tcttgagatg
    98581 ctgtagacat ccatacagct aaaacgacca gaatattaca aaggattgct tttaaaaaca
    98641 ttgatgctat agttgaatta accttagctt ctgccacagc tatagctttt gtagctgcat
    98701 ctcctgtcaa tgtagaagaa taaaacacaa gtgcgactaa caaaattgaa cctactaaat
    98761 ttgcaaaata aaccagtccc cagtttctta acatttttcc taatgttatt tttttgtcca
    98821 taagtgcaat agccattaaa gtgtttccag taaacaactc tgctcctgct actactacaa
    98881 gcataagacc tactggaaag accatagcac ttaaaaagct agctacccct gggtctatct
    98941 tgccaaaagt ttgactaact atcatactcc ccaatgcccc aaaacctata aatgctcctc
    99001 caaataaacc taataaaatt gcattttgtg tagaaatgtt tgctttttta atgcctgcac
    99061 ttatagttgc ttgtgcagtt tcaccaggtg tcaagaatcc tttactcata aatccttccc
    99121 ccttaaaaat tatactttcc cttgtctttt tatggcaata attatataat aacaatatga
    99181 tatataataa attttattaa cataaaaaat atactatatg cttatatata cttgtcttat
    99241 ataattatac tatttattat ataacaactt tgttaatttc gaaataattt atattgaatt
    99301 tgaaaaattt accttttgat tatttatttt acttttttat tattgaggta t
//
LOCUS       DBGJFK010000006        96593 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.006, whole genome shotgun sequence.
ACCESSION   DBGJFK010000006 DBGJFK010000000
VERSION     DBGJFK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 96593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96593
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.006"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            322..705
                     /locus_tag="ACOIAP_000507"
     CDS             322..705
                     /locus_tag="ACOIAP_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR2 nuclease fold domain-containing protein"
                     /protein_id="HGZ2637424.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKEYLYV
                     SSMYAIKEAKLESRINSGRVKQYDG"
     gene            1211..1594
                     /locus_tag="ACOIAP_000508"
     CDS             1211..1594
                     /locus_tag="ACOIAP_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGZ2637425.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLENKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            1596..1946
                     /locus_tag="ACOIAP_000509"
     CDS             1596..1946
                     /locus_tag="ACOIAP_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637426.1"
                     /translation="MNNTITINISIIYLLLAILACIALVYLIIVLVKLHKILNTVGTM
                     LNENTQNINTTLNNLPSVVENFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(2046..2504)
                     /locus_tag="ACOIAP_000510"
     CDS             complement(2046..2504)
                     /locus_tag="ACOIAP_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637427.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSNGKADLLYSCRLQKILKEIYINQSRASYMSGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(2552..3340)
                     /locus_tag="ACOIAP_000511"
     CDS             complement(2552..3340)
                     /locus_tag="ACOIAP_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2637428.1"
                     /translation="MKVVIIPGHTLTGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNVTTSTPGGTETIYKTNNEKTY
                     AERVNTRLATVFKNRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGVNKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALKQIDKL"
     gene            complement(3479..3916)
                     /locus_tag="ACOIAP_000512"
     CDS             complement(3479..3916)
                     /locus_tag="ACOIAP_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGZ2637429.1"
                     /translation="MDKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQSGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            complement(4151..4285)
                     /locus_tag="ACOIAP_000513"
     CDS             complement(4151..4285)
                     /locus_tag="ACOIAP_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637430.1"
                     /translation="MGILEGAAMIREIAIKIAKEKGITEQKAWPEAVKEFKEKYELVL
                     "
     gene            4755..4882
                     /locus_tag="ACOIAP_000514"
                     /pseudo
     CDS             4755..4882
                     /locus_tag="ACOIAP_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378761.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5329..5838
                     /locus_tag="ACOIAP_000515"
     CDS             5329..5838
                     /locus_tag="ACOIAP_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2637431.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVELEVDNLKVISEKLEIINLQLVQRKNMRRKMFHWLF
                     ILLCSVIVIVFMVLGGLNSPYLNWNYTNPETAVFGVAFHAFECLFVRLTPIVLIGAII
                     GSFLTRKKI"
     gene            5865..5975
                     /locus_tag="ACOIAP_000516"
                     /pseudo
     CDS             5865..5975
                     /locus_tag="ACOIAP_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            6229..6765
                     /locus_tag="ACOIAP_000517"
     CDS             6229..6765
                     /locus_tag="ACOIAP_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGZ2637432.1"
                     /translation="MQGGVDIRQVKSFVFPVISLIFLDQISKVLIGLFLMGFEIDITG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVIIGILHS
                     REISMKEYIYFCYRQFKR"
     gene            7523..8143
                     /locus_tag="ACOIAP_000518"
     CDS             7523..8143
                     /locus_tag="ACOIAP_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGZ2637433.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNAKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     KGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLKCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            8299..9081
                     /locus_tag="ACOIAP_000519"
     CDS             8299..9081
                     /locus_tag="ACOIAP_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HGZ2637434.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVATHEYRSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            9206..10132
                     /locus_tag="ACOIAP_000520"
     CDS             9206..10132
                     /locus_tag="ACOIAP_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637435.1"
                     /translation="MSDILSRISNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSSIDPEEIHTLESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARAIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNDTVEMVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            10146..10652
                     /locus_tag="ACOIAP_000521"
     CDS             10146..10652
                     /locus_tag="ACOIAP_000521"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2637436.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPNPYTEQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAVLGYWLARNYWGKGITTN
                     AVKEICKIAFEKYNLNKIHANVYSYNRRSSKVLEKCGFKIEEYCHNSIIKNRNMIDCH
                     VYSLIRTQ"
     gene            10661..11544
                     /locus_tag="ACOIAP_000522"
                     /pseudo
     CDS             10661..11544
                     /locus_tag="ACOIAP_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(11802..12602)
                     /locus_tag="ACOIAP_000523"
     CDS             complement(11802..12602)
                     /locus_tag="ACOIAP_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637437.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYASSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGASKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(12797..14395)
                     /locus_tag="ACOIAP_000524"
     CDS             complement(12797..14395)
                     /locus_tag="ACOIAP_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637438.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGIKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFNYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEVVKLIYNKYLELRSLSKLYKYIYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILEYLKNNGMDIVGTPDKKCGVLTYAKNTTNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRIATGKTALLSGFIKCGKCGSNMRITYKGR
                     KTDKDLKYYYICGTKKTLGADNCNCKNLNGPLVESLIIDKIKNCKEESIISTFNNNNI
                     KTGNIFNVLKSETNLLKNQILDKEKLIKNLVIELAKNTDSIASDYIVSQIENLNSEIN
                     ILKDKLNTLESSNANISSDSINLDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSNLGNLNIIYMGAEMDNSVSLSN"
     gene            14723..14899
                     /locus_tag="ACOIAP_000525"
     CDS             14723..14899
                     /locus_tag="ACOIAP_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637439.1"
                     /translation="MEINVIEIFPKDKAKLNEIEMNKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            15073..16203
                     /locus_tag="ACOIAP_000526"
     CDS             15073..16203
                     /locus_tag="ACOIAP_000526"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_process: GO:0051144 - propanediol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-propanol dehydrogenase PduQ"
                     /protein_id="HGZ2637440.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLVNSTYQVFEEIVPDPPIEVVVSGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSDTAKKYAQIAKLVGLGNANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILNNIK"
     gene            16444..16794
                     /gene="eutS"
                     /locus_tag="ACOIAP_000527"
     CDS             16444..16794
                     /gene="eutS"
                     /locus_tag="ACOIAP_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HGZ2637441.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            16802..17251
                     /locus_tag="ACOIAP_000528"
     CDS             16802..17251
                     /locus_tag="ACOIAP_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HGZ2637442.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELNYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKSKNIDEV"
     gene            17354..17929
                     /locus_tag="ACOIAP_000529"
     CDS             17354..17929
                     /locus_tag="ACOIAP_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGZ2637443.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            17922..19331
                     /locus_tag="ACOIAP_000530"
     CDS             17922..19331
                     /locus_tag="ACOIAP_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HGZ2637444.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     ILSKIDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGNLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFEDIL
                     MDENYDETNEVSIDNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGSYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFL
                     DREHGTIQILINKDNNYRNIAIIDDGVGFDSDNINKNSLGTYIIDSYITQMLKGNIER
                     KSNKNGTEILITIPTQINI"
     gene            19515..20948
                     /gene="eutA"
                     /locus_tag="ACOIAP_000531"
     CDS             19515..20948
                     /gene="eutA"
                     /locus_tag="ACOIAP_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HGZ2637445.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKVDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVIDTGCLDIGGRLIKIDKISKKITYISPKIDKIIKDNNLNLQVGTIATIENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISVDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCKYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYKKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            20966..22330
                     /locus_tag="ACOIAP_000532"
     CDS             20966..22330
                     /locus_tag="ACOIAP_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HGZ2637446.1"
                     /translation="MILKTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWILD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIRVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKYG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            22343..23224
                     /gene="eutC"
                     /locus_tag="ACOIAP_000533"
     CDS             22343..23224
                     /gene="eutC"
                     /locus_tag="ACOIAP_000533"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008851 - ethanolamine ammonia-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HGZ2637447.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRTGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            23244..23897
                     /gene="eutL"
                     /locus_tag="ACOIAP_000534"
     CDS             23244..23897
                     /gene="eutL"
                     /locus_tag="ACOIAP_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HGZ2637448.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            23908..24612
                     /locus_tag="ACOIAP_000535"
     CDS             23908..24612
                     /locus_tag="ACOIAP_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HGZ2637449.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRIDKVGAGIVTLT
                     ICGDVGAVKSALEAGEIAASRVGTLRTSHIIPRIHDEVTDALFKTKEPKVCEVSEDKE
                     KNFEVTLETTDNVSKNLSEKEDVILDVTENSGNIEKLYSDIDKINKEIETVDDILTEA
                     NKGKIENTNIDKKVLEQVKIENFDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLK
                     KEELINLVKKLSRRDR"
     gene            24615..26084
                     /locus_tag="ACOIAP_000536"
     CDS             24615..26084
                     /locus_tag="ACOIAP_000536"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HGZ2637450.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQDKLSKMSQEQIDKIVKAIA
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIISEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISD
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESKKLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHANDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSIDKEELINLLVQKLVKELG"
     gene            26170..26457
                     /gene="eutM"
                     /locus_tag="ACOIAP_000537"
     CDS             26170..26457
                     /gene="eutM"
                     /locus_tag="ACOIAP_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HGZ2637451.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            26584..27345
                     /locus_tag="ACOIAP_000538"
     CDS             26584..27345
                     /locus_tag="ACOIAP_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HGZ2637452.1"
                     /translation="MGVLTENEIKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKTYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKAQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLEEKLEDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            27358..27987
                     /gene="eutD"
                     /locus_tag="ACOIAP_000539"
     CDS             27358..27987
                     /gene="eutD"
                     /locus_tag="ACOIAP_000539"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization phosphate
                     acetyltransferase EutD"
                     /protein_id="HGZ2637453.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGK
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGLTLGL
                     KAPIKQSGDLEGTLSIKISTQHGEVELDKGLMVAKRHIHMTPKDAENFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKV"
     gene            28029..28754
                     /locus_tag="ACOIAP_000540"
     CDS             28029..28754
                     /locus_tag="ACOIAP_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HGZ2637454.1"
                     /translation="MNYDNLVDLIMEEIYKKVNSNEIKISNKPKAVIVFEQDTNKFNL
                     LKDEFEIVEFDKSIKECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMSGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFISFEDEICKFGVEIIKDLNAITKNKLNIKRELESTI
                     GSKKEDTKALDKDVLNLTSVESVKIDNEFSLDLRNRKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            28767..29039
                     /locus_tag="ACOIAP_000541"
     CDS             28767..29039
                     /locus_tag="ACOIAP_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HGZ2637455.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKGTYKEGFMVAA
                     DNAGAGNGDLVLISRGSSARESIEKAHVPVDATIVGVVDSFEVFDE"
     gene            29032..29583
                     /locus_tag="ACOIAP_000542"
     CDS             29032..29583
                     /locus_tag="ACOIAP_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HGZ2637456.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     VVGGETSYVNECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDNIVSIGVVE
                     SGKVCAGIKMLDRTLKSGELVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESEDVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            29595..30686
                     /gene="eutH"
                     /locus_tag="ACOIAP_000543"
     CDS             29595..30686
                     /gene="eutH"
                     /locus_tag="ACOIAP_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HGZ2637457.1"
                     /translation="MSINEIIIYVMVIFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEIMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGFAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            30688..31161
                     /locus_tag="ACOIAP_000544"
     CDS             30688..31161
                     /locus_tag="ACOIAP_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGZ2637458.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(31281..32330)
                     /locus_tag="ACOIAP_000545"
     CDS             complement(31281..32330)
                     /locus_tag="ACOIAP_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGZ2637459.1"
                     /translation="MSLNKLFQNLYIYNESELFYKNYYFAKQNPESLKLFIDNLDEDY
                     IVNNNLIIPYIYNEKIPQLMKDETYFECNSKDNVILIKHNRYTPQFVHEHIFFEMIYV
                     LSGKCYQVINHHNVHMKEGDICIVSPGVKHSIGVFDDSIIINVLIRRSTFEDAFFDFL
                     RNNNLLSSFFLNSIYKDKQNDYILFHTNNDKSIEISILEMLSEYNEQDRYYNNILNHL
                     IMVFFAKLLRDYEDSIEVPNVTKKGTLNHTNILTYIQDNYVDITLEELANKFHFSIPY
                     CSKIIKEIAGCNFTQLLQRIRLERAESLLMNTNIPIADISNNVGYPNVEHFIRLFNKK
                     YNMSPSKYRKNTTKV"
     gene            32503..33870
                     /locus_tag="ACOIAP_000546"
     CDS             32503..33870
                     /locus_tag="ACOIAP_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2637460.1"
                     /translation="MTTLKVVDEKNVPGIWRQRIGYGSSDLACNLIWQMISLYLLYFY
                     TDIMGLSAVAISFMFVVTRVIDGITDLLVGYCIDKTNTRWGKSRPYFLFGAVPFALFA
                     VLAFSVPDISLSGKLIYAYVTYIGLSLTYTIVNIPMASILPSLTDDTNERTALSTSRK
                     FFGFLGSTIVSYSALTLVGKFGGTDEALGFKVVMMLFAFIGCAIFLFTFSNVRERVEI
                     KSENVTLFQTIKSLKENKPWKLFALNILFMWTGFFIQSSALIYYFSYNVGSKSLATTV
                     ATIMSIIPILANFLVPILAKRLGKRNLYITSAAVQFIGLGIILIANLNISLIIAGSIV
                     SAFGYGIKESIYFSMQADPVDYGIWKTGINTTGTLNSVNGFLGKCAQAISGGLGGALL
                     AWGGYIAKAEVQPASALVAIKIMYVYIPMALLICSMITMKFYDLDKQYPKIKADLDAR
                     KISEE"
     gene            33901..35502
                     /locus_tag="ACOIAP_000547"
     CDS             33901..35502
                     /locus_tag="ACOIAP_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HGZ2637461.1"
                     /translation="MSNITNSIKDFRMEINQDFIDKAEKLKPILIEKLIKPKQIVNIK
                     MGKNDWEVIDTKSIDEISNISLGKGESICIDFGNHQVGYVNFKIKPIGSPPDAPTHLR
                     IKLGETLCEIGEDSSTYKGSISSSWIQEETMHIDILPDKINMKRRYAFRYLEIKVLDT
                     SPKYKVIVEDVSCNFVSSVDMSEINYLSNIDDDLIKIDKIALKTMQDCMQTVFEDGPK
                     RDRRLWIGDLRLQAITNYETFKNNDLVKRCLYLFAGLTQNRGQVGACLFIEPKLLVDD
                     TALFDYSLFFISCLHDYYEATKDMEILNELWKVAYIQAKLALERVGINGVVYDSDDWW
                     CFLDWKEGLNKQAGAQGVLIYALKQAHKLAIILGDNEKKEELEYEIDRVVQGAKNHLW
                     DEKQGFFVSGSEKQVSWISQIWCVLADVFDKETNTKILDNLLDNPPDMDIVTPYAYHH
                     LVECLILNNRKEKALECIRGYWGEMVKDGADCFWELYNPNDKYVSPYGSRIINSYCHA
                     WSCTPSYFIRKYFGRDSKEVTSKYK"
     gene            complement(35649..36248)
                     /locus_tag="ACOIAP_000548"
     CDS             complement(35649..36248)
                     /locus_tag="ACOIAP_000548"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637462.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGDAISIKVQL"
     gene            36418..37776
                     /locus_tag="ACOIAP_000549"
     CDS             36418..37776
                     /locus_tag="ACOIAP_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637463.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKIRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERIDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHESKISQNQKILLDEKFTLDDSIKNLSNIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFNDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            37769..38401
                     /locus_tag="ACOIAP_000550"
     CDS             37769..38401
                     /locus_tag="ACOIAP_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HGZ2637464.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNTSVEETFKKSGIPVKVDKSNGQVTFGERTMFDIDSDVLKPEAKEML
                     KMFVPKYMETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            38730..39887
                     /locus_tag="ACOIAP_000551"
     CDS             38730..39887
                     /locus_tag="ACOIAP_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HGZ2637465.1"
                     /translation="MIERNIKNKKNSKIKALILLFIVSISIYLTGCATSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFINTGNSDAILIQDGKTFTLIDGGDNDDEKLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALASKDLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILS
                     KLDKVDLLKVAHHGSRSSSSQEFLDKVSPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNNNTSKNDSFKNKQNT
                     SNSAEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYVK"
     gene            complement(40006..40641)
                     /gene="lexA"
                     /locus_tag="ACOIAP_000552"
     CDS             complement(40006..40641)
                     /gene="lexA"
                     /locus_tag="ACOIAP_000552"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HGZ2637466.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLKVKGESMINAGILDEDYVVVDKKNTAFNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(40745..41872)
                     /locus_tag="ACOIAP_000553"
     CDS             complement(40745..41872)
                     /locus_tag="ACOIAP_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2637467.1"
                     /translation="MNNDKKVIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNAECIKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRENGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(42195..43040)
                     /locus_tag="ACOIAP_000554"
     CDS             complement(42195..43040)
                     /locus_tag="ACOIAP_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637468.1"
                     /translation="MIYIIEILKISIINIFCFIGIFIVFGLIFSITESLNNKFIFSSF
                     GKIGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTVMIILIFKILLPDSYMKVTQNIDLNLYVSMINNLDISG
                     FIYIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFAISLITYLFGFDNLNISSLIVKYNIFVSLFMAIGLIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(43069..43440)
                     /locus_tag="ACOIAP_000555"
     CDS             complement(43069..43440)
                     /locus_tag="ACOIAP_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGZ2637469.1"
                     /translation="MKLKLLVEEYAVCRLNNDTKIPTWIDTERFYSITRTDDELSIVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILNCNGYEVE"
     gene            complement(43593..43853)
                     /locus_tag="ACOIAP_000556"
     CDS             complement(43593..43853)
                     /locus_tag="ACOIAP_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HGZ2637470.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGIAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(44042..44986)
                     /locus_tag="ACOIAP_000557"
     CDS             complement(44042..44986)
                     /locus_tag="ACOIAP_000557"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HGZ2637471.1"
                     /translation="MIENNSEKIKVLENDIKQLIIISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSPYEKVMLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSIVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYTKFRNIGKCL"
     gene            complement(45007..45861)
                     /gene="accD"
                     /locus_tag="ACOIAP_000558"
     CDS             complement(45007..45861)
                     /gene="accD"
                     /locus_tag="ACOIAP_000558"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGZ2637472.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(45876..47237)
                     /gene="accC"
                     /locus_tag="ACOIAP_000559"
     CDS             complement(45876..47237)
                     /gene="accC"
                     /locus_tag="ACOIAP_000559"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGZ2637473.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEENNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(47253..47705)
                     /gene="accB"
                     /locus_tag="ACOIAP_000560"
     CDS             complement(47253..47705)
                     /gene="accB"
                     /locus_tag="ACOIAP_000560"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGZ2637474.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQATSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADNFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(47975..48421)
                     /locus_tag="ACOIAP_000561"
     CDS             complement(47975..48421)
                     /locus_tag="ACOIAP_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637475.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILTTVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKGNDTNLKESEV"
     gene            48696..48974
                     /locus_tag="ACOIAP_000562"
     CDS             48696..48974
                     /locus_tag="ACOIAP_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637476.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(49103..49834)
                     /locus_tag="ACOIAP_000563"
     CDS             complement(49103..49834)
                     /locus_tag="ACOIAP_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637477.1"
                     /translation="MNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDANLRAVV
                     KRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEIPKEAL
                     SLKDMDSINLANNYLIDDSVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHNVNIAK
                     GESIDLRKIITKKIDSYYKYWEVTDNLPKDLDFIVSVSDKSVLSCEDMIIKGNKTGQA
                     VVKVILNDKNDLNTSQEVLITVNVK"
     gene            complement(49978..50622)
                     /gene="trmB"
                     /locus_tag="ACOIAP_000564"
     CDS             complement(49978..50622)
                     /gene="trmB"
                     /locus_tag="ACOIAP_000564"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGZ2637478.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(50760..51080)
                     /locus_tag="ACOIAP_000565"
     CDS             complement(50760..51080)
                     /locus_tag="ACOIAP_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HGZ2637479.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(51399..52085)
                     /locus_tag="ACOIAP_000566"
     CDS             complement(51399..52085)
                     /locus_tag="ACOIAP_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637480.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILYIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLDKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(52100..54577)
                     /locus_tag="ACOIAP_000567"
     CDS             complement(52100..54577)
                     /locus_tag="ACOIAP_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2637481.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMSGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLIAADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRHTRGVNALLPKETLSKIINKGSGYTRVLIESEEEMTENL
                     VNKLSEELSTEKYTVSNTINETKIISDARQKIMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTHILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPTVISPIGVIISVIVAIIVSLFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSVLLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKNILPLYVMNNEISGNGVTLSRLEGTDNIELYNSM
                     FAINYTNFEIKKQVTEAFKDKRSVILNEDTLKKVGLSIGDTITLSKDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRDLFGDTYNWSRTVE
                     EFYNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(54797..56194)
                     /locus_tag="ACOIAP_000568"
     CDS             complement(54797..56194)
                     /locus_tag="ACOIAP_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2637482.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLTLANQNNSSNGTVYFNAIKNNKNDYIYIIYFPLNISKVNMFFDGSK
                     FVGGKSIVFSIIGIIFLIILLSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     TDIYDSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSSI
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRLLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDYTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSKTKIEGTGLGLAITKQIIEVHGGNISVE
                     SILGLGSSFYIIFPI"
     gene            56693..57553
                     /locus_tag="ACOIAP_000569"
     CDS             56693..57553
                     /locus_tag="ACOIAP_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2637483.1"
                     /translation="MKKQKSPILLEMLGLFLGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(57794..58351)
                     /locus_tag="ACOIAP_000570"
     CDS             complement(57794..58351)
                     /locus_tag="ACOIAP_000570"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2637484.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKKDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(58541..59428)
                     /locus_tag="ACOIAP_000571"
     CDS             complement(58541..59428)
                     /locus_tag="ACOIAP_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2637485.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENGKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            59547..60746
                     /locus_tag="ACOIAP_000572"
     CDS             59547..60746
                     /locus_tag="ACOIAP_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HGZ2637486.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(60951..63506)
                     /locus_tag="ACOIAP_000573"
     CDS             complement(60951..63506)
                     /locus_tag="ACOIAP_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2637487.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKKYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETAMEGFVNDYLKPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     AYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILISVRVVHQLNKYSSIESMKNFKITNTKK
                     RILESVKHSNMTKVLSHKYMTQKKGLFVGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNIEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKIMKPTGEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFNIENYNSVSIKKTEDSNS
                     VELSEDIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFSLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINAPLYIGMIILNITISIVAVIIPVRQILKSDIISEINQK"
     gene            complement(63503..64189)
                     /locus_tag="ACOIAP_000574"
     CDS             complement(63503..64189)
                     /locus_tag="ACOIAP_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637488.1"
                     /translation="MSILVTNNLVKHYGKDETKVKALNGVSIEIERATFTAIVGTSGS
                     GKSTLLNIIGGLDSPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(64264..65172)
                     /locus_tag="ACOIAP_000575"
     CDS             complement(64264..65172)
                     /locus_tag="ACOIAP_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2637489.1"
                     /translation="MFILAFIICTVVIFIVSTKINQKRYDELSLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKLEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRVNLEPFSDIKLVHNKKWIIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVANQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(65174..65845)
                     /locus_tag="ACOIAP_000576"
     CDS             complement(65174..65845)
                     /locus_tag="ACOIAP_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637490.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQLIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKVCLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDENIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            66107..67171
                     /locus_tag="ACOIAP_000577"
     CDS             66107..67171
                     /locus_tag="ACOIAP_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reductive dehalogenase domain-containing
                     protein"
                     /protein_id="HGZ2637491.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEVNLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            67329..68015
                     /locus_tag="ACOIAP_000578"
     CDS             67329..68015
                     /locus_tag="ACOIAP_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637492.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSAMKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINVFKQKVKAFLNHFTTKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKNILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLQYIKTVYGMG
                     YMWLGERNEF"
     gene            68005..69036
                     /locus_tag="ACOIAP_000579"
     CDS             68005..69036
                     /locus_tag="ACOIAP_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2637493.1"
                     /translation="MNFKKFSCSSIYLIIAIGIIFTAILFNISIYIITDDLKLVTLLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQN
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVTTECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSEIGKGS
                     TFSIFLPNK"
     gene            69118..69783
                     /locus_tag="ACOIAP_000580"
     CDS             69118..69783
                     /locus_tag="ACOIAP_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637494.1"
                     /translation="MSILQVINLKKYYGQNSNITKALDSVTLYIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            69796..72213
                     /locus_tag="ACOIAP_000581"
     CDS             69796..72213
                     /locus_tag="ACOIAP_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637495.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKTKNILYQDKNFSSVGAYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGNLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIIGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESIPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIALSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMRADLFIILILSLVMFLTVRISLFKPTRIISKISAIEAMQYTE
                     TKFRKKVKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYKHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPCVKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYRLNLKVGDTVTFNIFSGNDIIKKKMKIMGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEIEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLQNMLYREGLNISIKAICISSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(72394..73185)
                     /locus_tag="ACOIAP_000582"
     CDS             complement(72394..73185)
                     /locus_tag="ACOIAP_000582"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2637496.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYINKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFRKNTQSNENISIIQGNAMDLSI
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFVAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSVFNVTRLHYVASDGL
                     ALYMREAVDSMNDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(73218..73805)
                     /locus_tag="ACOIAP_000583"
     CDS             complement(73218..73805)
                     /locus_tag="ACOIAP_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2637497.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNKYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGMAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(73983..75374)
                     /locus_tag="ACOIAP_000584"
     CDS             complement(73983..75374)
                     /locus_tag="ACOIAP_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637498.1"
                     /translation="MEKLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFS
                     PKGRFDSYPISITVGILVACFVMFSERLDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSLILFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIISPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSIFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCDTGVEKGLIGLMGGVIAAKGGTWGLVVGFILYFVLIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(75541..75747)
                     /locus_tag="ACOIAP_000585"
                     /pseudo
     CDS             complement(75541..75747)
                     /locus_tag="ACOIAP_000585"
                     /inference="COORDINATES: protein motif:HMM:NF020416.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase/BAAT C-terminal
                     domain-containing protein"
     gene            75932..76912
                     /locus_tag="ACOIAP_000586"
     CDS             75932..76912
                     /locus_tag="ACOIAP_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGZ2637499.1"
                     /translation="MSNNIKIIKKEINYFLLINFLLIAFTSIFLFLSISKPNNSELIS
                     SFSILFMYIPAFSAIVVLKKVSNYKFDSTVDKFLKFFAITTIVRIVISIAETFLIYSS
                     IISSTIDTLTSVYLLAVVLYNEFQFEVLNLSLSKNFKKVLGILLIFLILIIVRNIIDK
                     EGLSINVVNKFVTVFINIIINLCFGFNLFFGEEFGWRYFLQPRLQKIYGKKFGVLILG
                     FIWGIWHLPLCVTLYSPETPFYCVISQISYCTFIGIFLGYTYMKTKNLWAPILIHLVN
                     NTVSIILGGSIESIFTLESLLWSILVNAILFLPFLFAKEYKANNYDESSN"
     gene            complement(77128..78003)
                     /locus_tag="ACOIAP_000587"
     CDS             complement(77128..78003)
                     /locus_tag="ACOIAP_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HGZ2637500.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLD
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTVKKMSNYLYNDCFKIHYAVVDALIENRITE
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(78185..78871)
                     /locus_tag="ACOIAP_000588"
     CDS             complement(78185..78871)
                     /locus_tag="ACOIAP_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HGZ2637501.1"
                     /translation="MFGVIANSLAIAGGCIVGLVIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(78920..79459)
                     /locus_tag="ACOIAP_000589"
     CDS             complement(78920..79459)
                     /locus_tag="ACOIAP_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HGZ2637502.1"
                     /translation="MSDLNNKIIKERDENEASMNETKIYDILNKLNVEYDVVEHEAVY
                     TAEQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFA
                     SPERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVLKEDYLNFHPNINTKTVNISR
                     KGFEEFLEYLKYPIQSIDV"
     gene            complement(79505..80137)
                     /locus_tag="ACOIAP_000590"
     CDS             complement(79505..80137)
                     /locus_tag="ACOIAP_000590"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HGZ2637503.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNKNIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(80224..81306)
                     /locus_tag="ACOIAP_000591"
     CDS             complement(80224..81306)
                     /locus_tag="ACOIAP_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HGZ2637504.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLKNDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLKFIKNIY"
     gene            complement(81439..82785)
                     /locus_tag="ACOIAP_000592"
     CDS             complement(81439..82785)
                     /locus_tag="ACOIAP_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2637505.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGNGEKMIGILGHVDVVPEGDLESWNYPPF
                     EGIVEDGKLYGRGTQDDKGPTISAIYAVKVLMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDSEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTILVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKAAQIYALSIYELLKI"
     gene            complement(82854..84134)
                     /locus_tag="ACOIAP_000593"
     CDS             complement(82854..84134)
                     /locus_tag="ACOIAP_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGZ2637506.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEDIKGKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(84261..84518)
                     /gene="hfq"
                     /locus_tag="ACOIAP_000594"
     CDS             complement(84261..84518)
                     /gene="hfq"
                     /locus_tag="ACOIAP_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HGZ2637507.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNR"
     gene            complement(84632..85567)
                     /gene="miaA"
                     /locus_tag="ACOIAP_000595"
     CDS             complement(84632..85567)
                     /gene="miaA"
                     /locus_tag="ACOIAP_000595"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGZ2637508.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEAEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIYEINEKGKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQNQLAEKGIDYMHNRLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSNDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLEQYENIDELKNEIILYIKDSIK"
     gene            complement(85588..87552)
                     /gene="mutL"
                     /locus_tag="ACOIAP_000596"
     CDS             complement(85588..87552)
                     /gene="mutL"
                     /locus_tag="ACOIAP_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGZ2637509.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGMGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIRDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNDNLLESTPKNSNTTKSKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASEDEVNNINYLSEDSANDNIQEEFQVDGIRNEGNYYLGDSIKD
                     SEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKNDSMYLLDQHAAHERILYERYMEKF
                     YRQDINMQILLDPVIIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIFG
                     VPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLEK
                     CENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(87563..90406)
                     /gene="mutS"
                     /locus_tag="ACOIAP_000597"
     CDS             complement(87563..90406)
                     /gene="mutS"
                     /locus_tag="ACOIAP_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGZ2637510.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSGMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAEYADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKVLNDEVALMKQNDDKEKTNQDDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(90569..91303)
                     /locus_tag="ACOIAP_000598"
     CDS             complement(90569..91303)
                     /locus_tag="ACOIAP_000598"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637511.1"
                     /translation="MLTQMNFYQNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLVL
                     KKEKRNKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRNLNEDNLENIIKLKKEIISLL"
     gene            complement(91272..92285)
                     /locus_tag="ACOIAP_000599"
     CDS             complement(91272..92285)
                     /locus_tag="ACOIAP_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2637512.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKNASSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVAAVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEEASKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPK"
     gene            complement(92307..93077)
                     /locus_tag="ACOIAP_000600"
     CDS             complement(92307..93077)
                     /locus_tag="ACOIAP_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637513.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSVVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHSVVTIGEAVLGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MNSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQFVKKIVIRHRLTD"
     gene            complement(93052..93342)
                     /locus_tag="ACOIAP_000601"
     CDS             complement(93052..93342)
                     /locus_tag="ACOIAP_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGZ2637514.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(93474..93573)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(93698..93832)
                     /locus_tag="ACOIAP_000602"
     CDS             complement(93698..93832)
                     /locus_tag="ACOIAP_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HGZ2637515.1"
                     /translation="MNKNKNLAQCLDGIDIYPNMLEIVKQKLENYVNLVLGDTEKLSF
                     "
     gene            complement(93847..94020)
                     /locus_tag="ACOIAP_000603"
     CDS             complement(93847..94020)
                     /locus_tag="ACOIAP_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637516.1"
                     /translation="MIFLYYSGCEPQEEPCVVEINQESDYEITYLEYNFKEFIEGIFV
                     YKDECSIKTMLNQ"
     regulatory      94542..94631
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            94684..94860
                     /locus_tag="ACOIAP_000604"
     CDS             94684..94860
                     /locus_tag="ACOIAP_000604"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637517.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(94975..95331)
                     /locus_tag="ACOIAP_000605"
     CDS             complement(94975..95331)
                     /locus_tag="ACOIAP_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGZ2637518.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLESDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            95587..96507
                     /locus_tag="ACOIAP_000606"
     CDS             95587..96507
                     /locus_tag="ACOIAP_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HGZ2637519.1"
                     /translation="MNKKFRLYQVDSFTKEKFTGNPAGVITNADGLSESQMQKIAREL
                     NNSETAFIFNKLAKNHQENYDVHIRFFTPTNEVPICGHATIAAHYVRAVENQLNNKTV
                     FQKTGAGILPVDIIKKDNDYEIIMTQGKIEVSPPLQQTYQERLLNAFGILKEDIRTDC
                     PIAISSTGHSKVMIGIKELSTLNSLSPNLYELSKISQEIKCNGYYIFTLHDKETLQVH
                     GRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPIPNTEFIFEAVQGEAIKRKGKMLV
                     KVIISDNKPVEVKIIGKAVIAFSTNIEIEL"
BASE COUNT        34846 a        13821 c        13030 g        34896 t
ORIGIN      
        1 atatataaat aatattatca cagaaaactt taaaagaaaa cgttttatat aatataggta
       61 ttagattata tttttataaa gaagcaagag tactcaataa aacttaaaaa aattaaacag
      121 tttctaaaaa taccttgaaa atagaacctt atttgccatt tataaattat ataaaaaggg
      181 attatataaa gtcatatatg aaaaaactat attatactat cttttctttt tggaataaac
      241 tatactttaa atatggatat ttaatttaaa taaattttac agtattaaca gtaaattatc
      301 ttagaaagga atgtgcttta tatgtctaca gacaaagttg ttggaatcat agatgaagaa
      361 acggcagaac ttgcaggaat tgaatatact ggtaaaattt atgcttcttc tggtgttata
      421 aaacatataa agaaaaaaca tagatgtcaa ctgagtaagg atatttttaa tgatataata
      481 gatactataa aaatggtatt aaagtcacct gaatatatag gaagtcatcc taaaaaacct
      541 gggaaaagtg tggagtttat aaaaaaaatt gatgattata ttttagtggc tacagaatta
      601 gatacaaaaa aagaatattt atatgtctct tcaatgtatg ctataaaaga agcgaaatta
      661 gaaagtagaa taaacagtgg aagagtaaaa caatatgatg gttaacataa tattattaat
      721 ttccccgaaa atattgaaaa atattatcat ataggttata atattaatat acatgtagat
      781 atttattagt tagatttgag gttggaaaag gcacccaata cgctactata gagtagttaa
      841 tagagatgca ggatacgccg ccctgccaaa tctaattaaa ttaaaaagag aggattaatt
      901 cctctcttat tgttttttga gatactaatt taatctatat agaaagattg aaggtcattt
      961 atactaaaaa atttttagtt atatacatga aactaattaa ataagatatt tataatctat
     1021 atgtgataca tattatatac taataaaata aaaatatata gaaaatcctt ataaaaattt
     1081 aaattgtaat ggatagtaag taattaaaaa gaatttttat tgatttttaa gaatttagtt
     1141 agaaactata tcattatggt aaaaaatgta ttataatgtt tagaaatatt ataataaggg
     1201 gcgattaaac atgaatctat caaagaaaat agaagataaa agaaaagcta aacagagagc
     1261 tgaaaaagtt aagaaagcta aaattgctac agctggtgta gtattaggag ctgttactgg
     1321 tgcagtgagt ggagtacttt tggctcctaa atctggaaaa gagacaagag aagatataaa
     1381 agatgcttca caacaaattg ctgaaaagat aaatatgaaa actgtagatg taaaaggcaa
     1441 agtatctgag aagctagaga ataaaaaagg aaactttata gaatcaaaga aaaaaataaa
     1501 aaaatatata gataacaaaa aaagtgttga aaattctagt gaggaagata aaataataga
     1561 tattgttgaa ccagttagtg ttactgagga ataatatgaa caatacaata acgattaata
     1621 taagtataat atatttatta ttagctatac tcgcttgtat tgctttagtt tatttaatta
     1681 ttgtacttgt taaactacat aagattttaa atactgttgg aactatgtta aatgaaaata
     1741 ctcaaaatat aaatacaact ttaaataatc ttccgagtgt tgtagaaaat tttggcgaag
     1801 taggagaaaa tatgaaagat gtaacagagg tagttactga agttacagca gattttcttg
     1861 ttactaaaga cagtgttaaa tcaaatatgg atgttatagt tgatatattg actataatta
     1921 aaaatatttt tctagataaa aaataataag tttaatataa aagaagtcta agagatataa
     1981 tttaaacgac cttaaaatag tatttataag gtcgttttat tagcttaatt tgacactatg
     2041 tgtttttaat aattggtaat attcctcttt atcatttgaa catatatatc tatgcttgtt
     2101 gtttcaatta catccataag aacatcttta cattcaagct caaaatcttc cattccttct
     2161 aaatattcat catcttcatc aaaaaagata taagaattat ataaccattc ttcaaatttt
     2221 tcttcaagta tatcccaata cgaactccaa aataatccac aacctgacat ataagatgct
     2281 ctactttgat ttatataaat ctcttttaga attttttgta atctacaact ataaagtaaa
     2341 tctgcttttc cattgcttga tattaactca tttaaatctt ctattgacat taattcaact
     2401 ttaccacttt tatcataagg agtataattt tcatcaaccc atttatgtgg tttgttttct
     2461 ctgcatactg ttgctattaa ctctacaact tttgttctta tcattttttc tttatcctga
     2521 cttatttatt ttttataaaa taatcataat tttataattt atctatttgt tttaatgcta
     2581 atttaacagt ttcatatcta tcagcaccat ttattactac atcacctttt acaagtttat
     2641 tagcttctcc gcctacaaca taaacttttt tacctaaacc ttgcttatag ctagacgcct
     2701 caattattaa agaatccttc aattgccaat gtaaaatctg agcagccact ttatcagcgt
     2761 cacctgtata aacgattaca ttttcataca ctttatttac acctccccct tgagaatttg
     2821 atatagattt gtttagtata ccttctgcta tcaatttagc aactttatct ttattattaa
     2881 cataataatc tgtatctgct ttactatcta caaaacatac ttctattaat attgctggtg
     2941 caatagtatg attaagccaa taaaggcctc taacatcaga ctttgcgccc ctatttttaa
     3001 atactgtagc cagcctagtg ttcactcttt ctgcatatgt tttttcatta ttagtcttat
     3061 atattgtttc tgttcctcct ggagttgaag ttgtgacatt tgaattaaaa tgaatctgaa
     3121 cagccaaatc agtttcctgt ttatttgcta tagcacactg atctgctaaa tgattacttg
     3181 attcatcaac tcttcctgta taaacagtag ctccacctat tttaagccat ttaacaatta
     3241 agtcattcag tattcttgtt tctttacttt catttatata cccaacagct cctgtacctt
     3301 ttccagttaa agtgtgccct ggtattatta ctactttcaa attagcatct cctttacaat
     3361 taaatttaac ttctatttaa tatatgcata acttagaatt ttgtttcttt ttatatctta
     3421 cacttttatt ataatttatt ttgtaaaaat atagaatatt atttaaatag tgttaaagtt
     3481 ataattttgt atataagaca ttactcgatt gcaataattt tatagcatac tcatctattc
     3541 tatatccagt tctataatat atatgtttaa ttccagattg aattatagcc ttagtacagt
     3601 ttaaacaagg aaagtgagtt acataaatag aacaatcttt aaccgaaata ccttcttttg
     3661 cacaataata aagagcattt tgttcagcat gaatagttct aatacaatgt ccatctctca
     3721 tttcatgacc aacttcacta caatgcttat ccccagaaat actaccatta tatccagtag
     3781 acactattct gttttctgaa ttgacaatta tagctcctac ataagctcta tcacaagttc
     3841 ctctttcagc tactgtttca cacagtctca taaaatattc ttgccatgag catctatttt
     3901 caagtttttt atccaaatca tatacctcca aaatttatat ctaatatata ggatttatac
     3961 cttaaaaaat aatattaaaa acaaatttat atgacaaata aaatttatta atactgtttt
     4021 tattctaaat tattttactt taagttaaag ttacaaggaa tctaaaatta tatatattat
     4081 tcttcataat atgaatgtta taatataaaa aactgtctca ataaaataga gacagtttta
     4141 cagtcaaagt ttataataca agttcatatt tttctttaaa ttcttttacc gcttcaggcc
     4201 atgccttttg ttctgtaata cctttttctt tagctatttt aattgcaatc tctcttatca
     4261 ttgcagcgcc ttctaatatt cccattttta atctcccttc aaatatcttt ttgtatagaa
     4321 tataaatagt gctaagattt attacatgct gcatatacag tatctataca acacataact
     4381 tataaattcc ttttattttc atacgtcttt aaccgacata taattatatt caataagttt
     4441 taaaattatg aactcaatta taattatttt tattttttag aatctaaaca ctaaaaattg
     4501 taggtaaatt tgtcttatgc ctttataaat atttctacag ttttaattac tggacatatc
     4561 tatttttatt acaaaaagcg cttaaaaatc gagaatatcc gtataaacac tgtatatata
     4621 agcaaagcgg ttaaaggaaa aataagaaat ttacagaata gttcggaaag cccactcctt
     4681 tagatgtggt atggatatca taaatagtgt ataaaaagta ttgatacata cacatataat
     4741 gttaatataa gtatatggag aataaatata gaaaactcaa acaactgtca gtttaattaa
     4801 ttatcacttt gtattctgtc ccagatatag aagaaaaata tttaatatag aaggcttaga
     4861 agatatgtta ttcaaagaga ttgctattat gcatttttaa taatgaatgt taatgataat
     4921 ttaaagtcaa tcaacagaga attgtgtgtt aaaacatatg ataactttaa aatattacat
     4981 gataaagaaa taaataggtt aaaagaatta aaattaaatg gttataaatt aatatctagt
     5041 atgaagatat aaaaactata taggttgaga aacgagccta atattaatgt taatggtgtc
     5101 gacagatatt ttgttaataa aagtcttagg taatatgatt agtgagaata tgttgtaggt
     5161 tatgatttat tataattaag agtattgtag aacttcatgt agtatctaaa aaaaccacac
     5221 acctttaggc gtgggagttt cagttgaatg ttaaaatgcg ttgcttgaag caacaagcag
     5281 ttttgcctat aatatcggta acaactgaaa gaaaggtggt tagccctaat gttaagcgaa
     5341 aacattaaaa caatcagaaa gtcaaaagga ctttcgcaac aagaacttgc tataaaattg
     5401 aatgtagtgc gacaaacaat atctaaatgg gagcaaggat tgtcagttcc tgattctgat
     5461 atgttgattt ctatatcaga ggtacttgaa acgccggtaa gcactttact tggagaaact
     5521 attgttgagt tggaagttga taacttaaaa gtgatttctg aaaaattaga gattataaac
     5581 ttgcaacttg tacaaagaaa aaatatgaga agaaaaatgt ttcattggtt atttatttta
     5641 ttatgttcag tcatagtaat agtttttatg gtcttaggag gactaaatag tccttacttg
     5701 aattggaatt ataccaaccc tgaaaccgct gtttttggag tagcttttca tgcgtttgag
     5761 tgtctatttg tcagattaac accgattgtc cttatagggg cgattattgg aagctttttg
     5821 acacgtaaga aaatatgaag caactctgct ttttataata cagcaagtgt tccttaaaag
     5881 cgtcattcta catgacaatc gaggacgact atgtaaggaa gaatcttttt gatttccaac
     5941 taagcgaagt cattgaggac gacagaagcc caaaaccgta ttaagtgaaa gcaagactgc
     6001 tggacttata cgcccatgcg tcagaggcag aagcaaacaa agaaatgcta agtctgatag
     6061 catgatttgc aacaatttgt acaacgatta cgagtagaaa tatattacga aatcagaaaa
     6121 gaaatgactt gataatttac ccatgttata attattgatg tgaaattaat aaattgaaat
     6181 tcctttttgg ggtttaacga tactgagtaa ggaaaaagtg aatgactttt gcaaggaggt
     6241 gttgatatca gacaagtaaa gtcttttgtt tttccagtta tatccttaat attcttagac
     6301 caaattagca aagttcttat aggattattc ttaatgggct ttgaaattga tataactgga
     6361 aaatttttaa gattcaatcc tgttcaaaat acaaatctct cttatggagg aaattttatt
     6421 ggtattctat ctaatttatg ggtattggta ttgtttaaca ttttagttat cctagttatt
     6481 atatctggat atgcttttta caaatcaaaa aatgaacaaa cgagctattc agtaaaagta
     6541 attatgtctt gtggacttgc tggtacaata tgtagcttga tagataaatt attttgggga
     6601 ggaagtttag attttttgca gataccaagc ttttttattt tcgacttaaa agactgctat
     6661 cttactgttg cagaaataat atttgttatc ataggaattt tacatagtag agaaatatca
     6721 atgaaagaat acatatattt ttgctatcgt cagtttaaaa gataatttta gaagataaat
     6781 ttaagtttca aggtaaacta tttaatcaca gcaaatagtt ggctcacttc agattttggg
     6841 ctaaactgtg agcactcatt aggtctctgc tatctaacaa acggagcaca aaacggagta
     6901 caaaaatgaa aattaaatat tgaatataaa acacagttaa ttttgattaa aaagttggct
     6961 gttttttctt ttatagaaat ttaagcatag gtaataaaaa aataactgta tttatgtata
     7021 attggaggca ataaaaagcc agtaaaaccc ataaaatagg gtcatactgg caacatggta
     7081 agtttataag aagataatca aaaatttacg ctttatttta atttaaaaaa catactaaaa
     7141 atctgattat cccctagaac acagtaccta tccgcatata cacaggacta acaaagccat
     7201 tttactacta atttactact accgaatgag ccttgatacg ttgataagtc ctagaaatgc
     7261 aaaaatacgg tataaacacc tcagtattgt atcaaataaa actaaatatt taatagaaca
     7321 tggaacacga aaaaaggtgt tccttttcta tgataaggaa accaaagtta cacagctttc
     7381 ccagtttgag cttactttgc agaaaaatga caactggaaa ataataatgg aatagtttct
     7441 atgtaaatat atttttacta tcttacctaa ctaattgaaa gatgatataa tttaatcaaa
     7501 tatttggtaa ggagggatga atatgcattt aattgatttt atgaatgaag atattaaaaa
     7561 gaagcttgtt aaaaaaacgt ataaaaagaa agagactatt ctttttgctg agcaagaaaa
     7621 tgaatatgta attcttatga ttgacggtat tgcagaagca ttcatcttaa atgcgaaagg
     7681 aaacatctca actattcatc tttatagaag tggtagtttt tttggagaaa tggaacaatt
     7741 taatgatggg aaaaaacccg ttgaaattgt cgctttcaca gattgtaatg tatataaact
     7801 tcatagagat gattttttaa actggctaaa gggagatttt gaagctacaa aatttctgat
     7861 tcgagaaata tctagtaaat tagttgtaaa tgctgaatta attgaagaat tatcatcttt
     7921 aagtgttaaa gaacgacttc tgaagtgtat atccttacac tattatagaa gtgaattaaa
     7981 tctgcttacc aaaaaacagc ttgctagcga agtaaacgct ccaattagaa gcattaatcg
     8041 tgctataaat gaatgtgtac aagaacatct aattgcttat gaaaacaaaa gatttagtgt
     8101 aattaatcag cgagaggtat taaagaatct tcctacaaca taagtataat ttcaaaaaag
     8161 cattggataa taattattca atactttttt atttcgggtc aagtgaccta ttttttttta
     8221 tttcttcatt atataatact cctatgcata attatgttgg attgatagct aataaaagaa
     8281 agtgagaggt gttatattat gactaaaaca caacaggaaa tgatacaaaa cgtattagaa
     8341 ttttccaaaa gagatagtag gataatagga cttgcaatta gcggttctta tatcacaaaa
     8401 tcgttagatg aatattctga tttggatttt ctgattgtag cagatgataa atcctatgaa
     8461 gaagttatcg aagagagatt acttattgtg gaacagtttg gaacattagt ttctgctttt
     8521 actggcgaac acgttggaga acctcgattg ataatttccc tctatgattc ccctgttctt
     8581 catgttgatt ttaagtttac aaccttagat ggtttactag atagggttga agattcagct
     8641 attctctatg aagaaaacaa ctgcataaca gaaatttatt ctaaaaaaga agcatacttc
     8701 ccaactccag acttacagtg gattgaagat agattttgga tttgggttca ttacgcttgc
     8761 actaagattg gacgtagaga actatttgaa acaattgatt ttttatcttt tttaagacaa
     8821 tcagtacttg ccccattgat acagcttctc ttaggtaaat tacctcgtgg agttagaaaa
     8881 atcgaattgg atgcacccca atatattgaa gcattagaaa agacggttgc tacccatgaa
     8941 tatagaagct gtgttaatgc attgcaggct actatcaacc tgtatcttga gttaagagag
     9001 gaattatcac aaagtcctat tgtccgaaag gttgaagctg aaagggttgc attacagtat
     9061 tttcaagatt taatcaaata aacccaaagt aaaaaaacat tgaatggtaa atattcagtg
     9121 ttttttcatt tttggtcaaa cgacctagat tagttgttgt aaccattcta taattatttt
     9181 gaaagtaaca gtaaggagga taactatgag tgatatttta agtagaattt caaataaaat
     9241 tggggataag aatatagttg ataagttatc agctctatca aaatcagatt tgaactcact
     9301 tctattagaa gtgtttgata gacaagcaaa tactttaact gcaactgata ttctaaagtc
     9361 ataccaacta aatagattta ctatccctag cagtatagat ccagaagaaa ttcatacttt
     9421 ggaatcaaaa ttattgagaa aagcattcaa tatggatatc aagacgatta tgctttctcc
     9481 atctgctcca ttaggtagtt gtagcgtttt tggctccgta gatcaatata acgtagtaag
     9541 tgctctacga gggacagaaa cacttgcaga cccctcaaat atgttggcaa taattattgc
     9601 tgataaatta aaaagaaaag aagaaaataa taccatacct atccacatgg ctactactgc
     9661 tagggcaata agagcacaaa attttgtagg taaaggttta tattcacatt ttggcttata
     9721 ttgtatggtt tcatctggta tagatacagg gtcttacact tgtgaaaaaa tgttgttaga
     9781 aaagcactta aactattata aagatatatt aagtgaaata gaaaatgttc gtttctctat
     9841 tattctacgc aaaagaaacg gatacaaaga taatgacgga tttttcgaca gaatggttga
     9901 aactatcaaa cttatttttc ctaatataga gttatcaatt cataatgatg atgttgataa
     9961 taattattat aaaggtatca atttcaaatt atcggtcaaa caaggaaatg ataccgttga
    10021 aatggttgat ggtggatttg ttgactggac ttatcaaatg cttggaaata aaaaagaacg
    10081 ctgtttgata agtggtattg gcttagaaag atttcttgta gctgtttcat aaaaggagaa
    10141 gaaaaatgga acttatagag tggaattatg cttatattac cgatttagtt gagtttgcga
    10201 atgataaaga aattgcaaag aatcttcgtg acaacttccc caacccttat acggagcaaa
    10261 acgctagaga ttttattagt ttttgtttgg caactccaga tgttaaacaa cttagctatg
    10321 ctatttttta tcaagaaagg gctattggaa gtatcagcct aacatttgaa gaagatacct
    10381 ctattaataa aaatgctgta ttaggttact ggcttgctag gaactattgg ggtaaaggga
    10441 taacaacaaa tgcagtaaaa gaaatatgca aaattgcctt tgaaaaatac aaccttaaca
    10501 aaattcatgc taatgtatat tcctacaata gaaggtcaag taaagtattg gaaaaatgtg
    10561 gttttaagat tgaagaatac tgtcacaatt ccataataaa gaatagaaac atgattgatt
    10621 gccatgtata tagtttaatt cgaacgcaat agcatttaaa ggacgccatt atcttatgaa
    10681 tattctgaac aataagccac taggtgcgaa aagcattgat atggttaaat tatcagacgc
    10741 taaaagctgg gctatccgaa tgagtgaaga tgggtgtgct tataaatcca ttgacaatta
    10801 taagcgttca ctgaaagcgt cgtttttcat ggcaattcaa gacgactata ttagaaaaaa
    10861 tccatttgat tttcagttaa gtgatgtttt ggaagataca acagaaccaa aaatcgctct
    10921 aacaacagaa caggaaatgg acttattatc ctttatggag agcgataata cttattgtaa
    10981 atattatgat gatgttgtta tcctcttaga aataggacta ctcatttctg aattatgcgg
    11041 tttgacttta gaattggata tgaaaaataa agccattatg gtagaccatc aattgttgag
    11101 tgataccaag attggctatt atgtagaagt tccaaagacc acacagggta agcgagaaat
    11161 tccaatgact gagaaagagc ttatcaatca tttgaacgta tcgtggaacg gcgtaagaac
    11221 gctaaagcaa aaccaatcat tgttgatgtt tatcaaaact tcttattcct taaacgtgat
    11281 gggttaccaa agtaagcaac caattatcaa agcatgttaa gagcgttagt caagaagtat
    11341 aataagactc atgaggacaa gctaccaaag attacgccac atacctttag gcatacgttc
    11401 tgtaccaata tggcgaacaa aggaatgagt cctaatatat tacaatatat aatggggcat
    11461 aaaaacatta ctatgacgct tggctattat gcacatggtt catttagttc tgcaagagct
    11521 gaaatggaac ggttatctgc ctagtggtat gactagagtt tactacttat ttactacttt
    11581 tgatggcatt cttatacggt taaatgccaa cttatgcaaa gtatcttcca aaaagaaaat
    11641 gccgatactc cttgtagata caggatatat cgacatttac caacttatga aaagataatc
    11701 aaatttaata taagttttta tattaaaaaa atgattactt taaagaaatc attttttatt
    11761 ataatcactg agacatcaaa tattctaaat aaaattttta cttatctgga attgtatatt
    11821 ttttctataa tattaactac agcgtacatt gcccaggcac agatagccaa tacaaatact
    11881 cccatcatta ctaaatctaa tttaaacact tgagaaccat atactatcaa atagcctatt
    11941 ccatatcttg aaactaaaaa ttctccaact attacaccta cccatgccat accaatatta
    12001 attttagtta aatttattaa atttcctgtg tttgcaggta atatgagttt aaataatatt
    12061 tgagatttac tagctccaaa actctttaac atcttgattt tttcttcgtc tatattcata
    12121 aaataattat aagctgaaag tatagtaaca acaaccgaaa tagttacagc tgttacgacg
    12181 attccttcta ttccagcacc tacccaaact ataattatag gagctaaagc agtcttagga
    12241 agagcattta aaactaccaa aaaagggtct aatatttttg ataatttttc tgaccaccaa
    12301 agagcaattg ctaccaaaat acctaataca gtacctataa caagaccaag aacagtttca
    12361 tatacagata ttccaatatg tttaaataat tgaccactag atgcatattg aataaataaa
    12421 ttgtaaatat cacttggttt gctaaataga aatgtattta taacatttaa gtcagctaaa
    12481 agttcccaga ttacaataaa accaattaaa attaatagct ggtagaataa tacatttctt
    12541 ttttctcttt ttacaccttt aacatagttt atatatcctt cagatctttt attaagcctc
    12601 atgtgtatct agctccttcc ataatatgtc gaaatacttt tgaaaatcag gaactttacg
    12661 tgttttaaga ggcgtttttg ttccatccat gttaagttca atatcgtaaa tattttttat
    12721 ggtagctggt cttttagata gtattgcaac cttatctgat atgcttattg cttctactat
    12781 agctaaaaaa gtgcaactaa ttgcttaaag aaacagaatt atccatttca gcacccatat
    12841 aaataatatt aagatttcct aaattgctat cccaaactat actattaata atagtagata
    12901 ataacaatct cttatcatct aaactggcat tatcaacttc atcattaaat ctcttcaaat
    12961 tactaacaat aatatcaaga ttaatactat cactactaat attggcatta ctagactcca
    13021 aagtattaag cttatctttt aaaatattaa tctcactatt taagttctca atttgagaaa
    13081 ctatataatc agaagcaatg ctatcagtat tttttgcaag ctctataact aaatttttga
    13141 taagtttttc cttatctaaa atttgatttt taagtaaatt agtctcggat tttaaaacat
    13201 taaaaatatt accagtctta atgttattat tattgaatgt acttatgata gattcctctt
    13261 tacagttctt gattttatct ataattaaac tttcaactaa tggaccatta aggtttttgc
    13321 agttacaatt atcagcgcca agcgttttct tagtgccaca aatataataa tactttaaat
    13381 ctttatcagt ttttctacct ttataggtaa ttctcatatt agaaccacac ttaccacatt
    13441 ttataaaacc agataaaaga gctgtttttc cagttgctat ccttggggtt ttatcacgat
    13501 ttttatctag ttgattttgt acttcaagcc atatttcagg ttctatgact ccatggtgtt
    13561 ttgcaattgc tgctattgag ttagttgtat ttttagcata agtaaggact ccacattttt
    13621 tatctggagt acctacaata tccataccat tatttttaag gtattctaaa atttcatcat
    13681 tagcttttac atatgctgga tttctaagta ttctagataa agaactaggg tcaaatttac
    13741 caccacgagg acctcttatt ccattattat agatatattt atataactta gataaggacc
    13801 taagttctaa atatttattg tatattaact ttacaacctc catttgctca tcatttactt
    13861 gaagcttata catacttctt tcttttaggt tttcatctaa gaatgtgatt ttttcgctgt
    13921 taaatccatg aggtgtattg cctccaagcc atctaccact acgagctaat tcatacatat
    13981 tatcttttat acgttctgct attgtttctc tttctagttg agcaaataca cttgatataa
    14041 acatcatagc tcttcccatt ggagttgagg tatcaaattg ttctttgata gatataaatg
    14101 atatgtttag ttcatttaat ttttctatta aggtagagaa gtcagataca tttctcgata
    14161 ttctatctaa tctatagcaa actaggtaat taaatttctt atccttggca tcctgcatca
    14221 ttttcttaaa ttgtggtcta tctatattac taccactaaa cccctcatct tcatatatca
    14281 aaaaatcttt tataccaata gactttgcat aatcaataca taattgtatt tgattttcta
    14341 tagagtcgcc ttttccagta aatcttgatt ttcttgaata aattgcagct ttcaaaatta
    14401 aaacctccta taagttagga catatattta gaattattta tatacaatct tttaagtaaa
    14461 cttattagaa tgaatttatt aattaggtaa atttatataa ttctactttt tataatatat
    14521 gactatttat tttatttctt tactattcaa gttctaaatc aataataaat tttggtattt
    14581 aattgtatca ggacaaatct ctaatttcat agattattaa tataaaatca taagttagta
    14641 tgaaaaaatt aaaatttaaa tattttaaaa gataattttt tggaactaat agctataaca
    14701 aaaatttata gggggattgt atatggaaat caatgttata gaaattttcc ctaaagataa
    14761 agctaaactt aacgaaatag aaatgaataa agctagttgg tttgtaaata taataagtaa
    14821 aaaatatcct aaagaagctt taaatgaagc atttagtact ttagaaaaag aattaaatat
    14881 aagtaaagct aatacataag ctttgattat tgattttata tattattgaa tttgtacact
    14941 atgacttgac attatattaa tcaaatagta tatttttaaa tatagcacaa tgaagtgtta
    15001 aaagagcaat ggagctccat agataaagtc tatggagctt ttttgcgtat ttaacttaag
    15061 gaggacagaa atttgaataa ctttgagatt aaaactagaa taaaatttgg agaaggttca
    15121 ctgaaagctt tacaagaact aaaaaacaaa aatgtattga taataacaga cccatttatg
    15181 gtgaaatcaa aaacaataga taaaataaca tctaatttgg taaactcaac atatcaagtt
    15241 tttgaagaaa tagtaccaga cccaccaata gaagtagtag tatcagggat agaagcattt
    15301 aaatctataa atccagatgt aataatagca ttaggtggtg gctctgcaat agatgcagca
    15361 aaatctataa tggacttttc taaaaaaata ttaaaaatta acgaagtaga gtttatagca
    15421 ataccaacaa caagtggaac aggttcagaa gtaacatcat ttgctgtaat aacagatagt
    15481 caaaaaaaat gtaagtatcc attagtaagt gatgatttac ttccagacat ggcaatacta
    15541 gacccagagc ttgtaaaaac tgtaccgaac tttataacag cagatacagg aatggatgta
    15601 ttgacacatg ctatagaggc ttatgtatct acaaattcta atgatttttc agatgcacta
    15661 gctgaaaaag ccataaaatt agtatttaaa tacttaataa aagcatataa agatggaaat
    15721 gatatagaag ctcgagaaaa aatgcacaat gcatcttgtt tagcaggtat ggcatttaac
    15781 caagcatcac ttggaataaa tcattctatt gcacatgtat taggtggaaa attccatata
    15841 ccacatggaa gaacaaactc tatattactt cctcatgtaa tagaatataa ttcatcaata
    15901 gtaggatata ctaacacaac ttactctgat acagctaaaa aatatgcaca aatagcaaaa
    15961 ttagtaggac ttgggaatgc taatataaga atatctgtta gaaatttggt aaatgaaata
    16021 aagaaactac aaaaagaaat gaatatgcca actaaattga cacagtgcaa attaagttta
    16081 gaagatataa ctaatgaaga aagagaaata gcaaagcttg ctataaaaga tacttgtaca
    16141 ttaactaatc ctaaggtacc aactgaagat gatataataa acatattaaa taatattaaa
    16201 taactacatt ttattacatg taaacataat cttatacaaa taaggaaaat gtttttaaaa
    16261 atataaatta tatattgaca aatataaaac ataaaactat aatgaaagta tcacaaaggc
    16321 gtgatacttt attagaaagc aatggagctt cttaggaata ttaatattat tcttatggag
    16381 ctccttttat tttaagcaat tatcttttta gtaaactata tttaaagaaa gtagggaata
    16441 aatttgactg aagaatctaa gcaaagagtt attcaagaat atgttcctgg aaaacaggtt
    16501 acattagcac atatcatagc taaccctaat gaagatatat ataagaagtt aggattagta
    16561 cttgataaaa aagatgcaat aggaatactt acaataacgc caagtgaagc gtcaataata
    16621 gcagcagatg ttgctacaaa ggcttcaaat gtatctttag gttttataga tagatttagt
    16681 ggttcagtag taatatcagg tgatgtaagt tctgtagaat cagcgttaaa tgatgttttg
    16741 gaagtcttag gaaatatgtt aaacttctca tctacaaaaa taacaaggac ataataatac
    16801 aatgaagaat ataatattta tgggaaagac agggagtggt aaaactactt tatgtcaaaa
    16861 attagaccag ttagaattaa actataaaaa aactcaatca gtggaacttt ataataatgc
    16921 aatagacact cctggtgagt atatggaaaa tagaaacctg tacaatgcct taataacaac
    16981 atcagcagat gctaaaatta tagcaatagt gtatgatgcc acacaagaag aaaattatat
    17041 agcaccaggt tttgcaagta tgttttgcaa agacgtaata ggaattataa ctaaaataaa
    17101 taaagctact gaaaatgaag tcaatatagc ttatgaaaga ctatcactag caggagcaag
    17161 tcaaatcttt aaaatagaca cagttgataa tattggactt gaaaaattat ttaaatatct
    17221 agaaaaatct aaaaatatag atgaagttta aggggaaaat atttttttat tcaaaaatat
    17281 tattaaagta tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa
    17341 gcgaggtagg aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat
    17401 ggatacaaaa gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg
    17461 atttgaagct gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga
    17521 gatgccaata cttgatggta taaaagcagg aaaaattata tgtaaagaaa atctagctgg
    17581 tggagtactt ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat
    17641 aggtgcttat ggatacttgg taaagacagc aagtgaaaaa tcacttattc caactataga
    17701 aatgtgttta aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa
    17761 ttctaaattg aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt
    17821 taagatttct gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac
    17881 cacaatgatg gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa
    17941 aaatatcaac tgcacaaaca tacttaaata ataatgaaat tgaaaaaatt atagaagtat
    18001 caaaatcctt agatttaatg gcttcttttt atgaggctga tgtttttata gatatactaa
    18061 gtaaaattga tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt
    18121 actgtgaaaa tgttataggc aaaaaggctt taattgaaaa tgaaccagga gttataaagt
    18181 gcttaaaaac aggagaaaga gtaagagata taaaagcttt gacacaagaa tataaactgg
    18241 tcaagcaaaa tattcagcca ataacgctag atgacaaagt tttagcagta ttaatagttg
    18301 aaaaagatat aagtagtgaa gtcaagaatg agtttaacgc tagtgaagac gaagaaaata
    18361 aaaatttaca tcagtttata aaacttatag gaaataatga ctttttagtt gataatttaa
    18421 attcagctat actaattttt gataaaaatg gaaatttaaa aattaaaaat cgtattgcaa
    18481 ctgagatata taaaaatctt gggtttggat atgatataca agatatgcat tataatgact
    18541 tagatataga aaccaataca tttgaagata tattaatgga tgaaaattat gatgagacaa
    18601 atgaagtttc aatagataat atgtttttta aaataaaaac catatacatc aaagatgatg
    18661 aatttaaggt ttgcaaaata gtacaagata taagtgattt aaagcgaaaa gaagaagaat
    18721 tagttttaaa aacagtagct ataagagaag ctcatcatag agtaaaaaat aatcttcata
    18781 cagtaatatc tataataaaa aaacaaagta gattatctca aaatgatgaa gttaagcagt
    18841 gcttggataa tataataaat agggtatttg caatactttc gactcattat ttactatcta
    18901 aagaagttga taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc
    18961 aaggtagcta tttatttagt aaagatatag atatacgtat aactggtgaa gattttaaaa
    19021 ttagtggaga aaaagcaaca gcaatacttt tagttataaa tgaaatacta caaaattgtt
    19081 atgaccatgc ctttttagat agagaacatg gtactataca aatattaata aataaagata
    19141 ataactatag aaatattgct attatagatg atggagttgg atttgatagc gataatataa
    19201 ataaaaatag tttagggaca tatataatag atagttatat aacacaaatg ttaaaaggaa
    19261 atatagagag aaaaagtaat aagaatggta cagaaatatt aattactata cctacacaaa
    19321 ttaatattta aataataact catctacaaa gtagtagttt taattgagca aagaggctta
    19381 aggttattaa tagattaagt taattgaatg tatttataaa aattataagt atatattcaa
    19441 tttaatagat atttattata actttaagcc tctttgcttg tttaagacat acttaaattt
    19501 taggaggtga gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta
    19561 ctactcagtt aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcagtac
    19621 ctagaataag tatagtagac aaagaaatta tttataaaag taaagtttat ttcactcctc
    19681 ttatttcaaa taatgaaata aatggtcaac aaataaaaga catagttgaa aatgaatata
    19741 aaaaagcaaa tatatctaaa gtggatatac atacaggagc agtaataata actggtgaaa
    19801 cagctagaaa agaaaatgca aatgatgtgc ttcatacttt gagtggattt gctggggact
    19861 ttgttgttgc aacagcagga cctgatttag aaagtataat atcaggaaaa ggggctggag
    19921 ctcatattta ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa
    19981 ctagtaatat agcttcattt aaaaggggtg aagtaattga tactgggtgt ttggatatag
    20041 gtggaaggct tataaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa
    20101 tagataaaat cataaaagat aataatttaa atcttcaagt aggtacaata gctaccatag
    20161 aaaatacaaa accaatagta gatataatgg ttgacctatt aatggaaagc ataggattaa
    20221 aaaaacagac acctttattt gattttataa taaccaataa atcaataagt gtagatgaaa
    20281 atattaaaaa tgtttcattc tctggtggag tagctgatta tatttactat gatggggaaa
    20341 taaaagatta ttttgaatat ggtgacttgg gaattttact tggacaagca ataaaaaatt
    20401 gtaaatacct taaaaaagta aatgtagtta aatctatgga aacaataaga gctacagtgg
    20461 ttggagctgg ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa
    20521 agtttccact taaaaacttg ccagttttaa aattatcaat tgatgaagaa acaggtactt
    20581 caaaacaaat cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt
    20641 tacaaaaagt tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag
    20701 agtatgccaa aggatttgta gatggaatgc aacaaattat agaaaatgat ttacctttta
    20761 tagtaattgt tgaaaatgat atggcaaaag tattaggtca agctatatat gcattattaa
    20821 attataaaaa agagattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg
    20881 acattggaaa acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt
    20941 ttaattaata gaaggaggta agtaaatgat tttaaagaca aaattatttg gacgtactta
    21001 tcagtttaaa ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa
    21061 attagcaggg cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc
    21121 acatataaaa ttggaggata taagaaataa tcctgcagta gcatatgaag aagatgaagt
    21181 aacaagaata atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac
    21241 agtatccgaa cttagagaat ggatattaga ttcaaatact acaagtcttg atataagaag
    21301 aatatcaaga ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat
    21361 ggacttagtt tatgcagcca aaaagataag ggttactgcc cactgtaata caactatagg
    21421 agaacaagga acattatcag caagacttca acctaatcat ccaacagatg acccagatgg
    21481 aatacttgca tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt
    21541 aaatccagtt gatgactctg ttgaaagtgt tactaaagta ttaaaaagat ttgaagaagt
    21601 aaaacaaaaa tatcaaatac caactcaaac atgtgtattg gcacacgtta ctacacaaat
    21661 ggaagcaata agaaatggtg ctcctgcaga tttgatattc caatctatag caggttctga
    21721 aaaaggaaat gaagcatttg gatttaatgg cgatactata gaagaagcta gacagttagc
    21781 tttgaagtat ggtacagcta caggacctaa tgttatgtat tttgaaactg gacaaggttc
    21841 agaattatct tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgtta
    21901 tggatttgct aaaaaatacg aaccattctt agtgaacaca gttgttgggt ttataggacc
    21961 tgagtactta tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg
    22021 taaactacat ggcttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga
    22081 ccaaaatgat atggaaaact tagctatact attaacaaca gcaggatgta cgtattttat
    22141 gggaatacct catggagatg atgttatgct taactatcaa acaacaggat accatgaaac
    22201 agcatcactt agagaaatgt ttgggctaac agcaataaaa gaatttgatg cttggatgga
    22261 aaagatggga ttctctaaag atggtaagtt aacagagttg gcgggagacg cgtctgtatt
    22321 attaggatag gaggtattta atatgaatga gaaggattta aaagcattag tagaacaatt
    22381 agttggacaa atggttggag aattagatac taatgttgta tctgaaactg ttaaaaaagc
    22441 aactgaagtt gtagtagaca acaatgcttg tatagatgat ataacagaag ttgatataag
    22501 aaagcaatta ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa
    22561 aacacctgca agattaggta taggaagaac cggcactaga tataaaacag aaacagtttt
    22621 aagatttaga gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga
    22681 atttataaaa gaaaataata tgtttgcagt agaaacttta tgtaaagata aagatgaata
    22741 cttaacaaga ccagatttgg gaagaaaatt ttctccagaa actataaata atataaaatc
    22801 taaatttggt acaaatcaaa aggttttaat attagttgga gatggactta gttcagctgc
    22861 gatagaggca aatttaaaag actgtgtgcc agctataaaa caaggtctaa aaatgtatgg
    22921 tatagattca agtgaaattt tatttgttaa acattgtagg gttggtgcta tggaccactt
    22981 aggtgaagaa ttaggctgtg aagttatatg catgttggtt ggagaaagac caggactagt
    23041 tactgctgaa tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaggc
    23101 aaaaagaaca gttatatcaa acattcacaa aggtggaaca actgcagttg aagcaggtgc
    23161 tcatatagct gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa
    23221 ataaagtcga gggagtgtag aatatgaaaa acgatgtaat tcgtcctaat atactaggaa
    23281 ttaaaataat ttcgaatata agtccagaaa tggcacaaaa actagaacta aaatcacatc
    23341 acaaaagttt aggtttaata actgcagatt gtgatgatgt tacgtacaca gctcttgatg
    23401 aagcaactaa agcttcagaa gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg
    23461 caaatgcttc aacaaaactt gctggtgaag tattaggaat aatagcagga ccaagcccag
    23521 cagaagtaag aagtggtcta aatgcagtag ttgattttct agaatatgga gcaactttta
    23581 taagtgcaaa tgatgatgat tcaatagcat attatgctca ctgcgtatca agaacaggta
    23641 catacctttc agaggtagca ggaataagag aaggtgaagc attagcttac ttagtagcac
    23701 caccacttga agcaatgtat gcactagatg cagcaatgaa agcagcagat gttaaaatgt
    23761 gtgaattatt tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc
    23821 aatcggcttg taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca
    23881 atccaacagg attttaagga tagttagatg gatgctatag gcttaataga agtaatagga
    23941 tatgttgctg caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta
    24001 agaattgata aggttggggc aggtattgtt actttgacaa tatgtgggga tgttggtgct
    24061 gtaaaatctg ctttagaagc aggtgaaata gcagcttcca gagttggtac attaagaaca
    24121 tcacatatta taccaagaat ccatgatgaa gtaacagatg ctttattcaa aactaaagaa
    24181 cctaaagtct gtgaagtttc agaagataaa gagaaaaact ttgaggttac attggaaaca
    24241 actgataatg tatcgaaaaa tttatcagaa aaagaagatg taattttaga tgtcactgag
    24301 aatagtggaa atattgaaaa attatatagt gatatagata aaatcaacaa agaaattgaa
    24361 acagttgatg atattttaac agaagctaat aagggaaaaa tagaaaatac taacattgat
    24421 aaaaaagtat tggaacaggt taaaatagaa aatttcgatt ttgatagaga tgacctatca
    24481 aagaacagcg tgaaaaaact taaagctatg gctaagaaat tagattcttc aataacttat
    24541 aaagatttaa atgttcttaa aaaagaagaa ttaataaact tagttaaaaa gcttagcaga
    24601 agggatagat agttatgaca ctcttagata aagatttagt atctatacaa gaagtcagaa
    24661 ctcttgtaag aagatctaaa gtggctcaag ataaactttc taaaatgagt caagagcaaa
    24721 tagataaaat agtaaaagct attgcagatg cagcatttaa taatgctact aaattagcta
    24781 aaatggcaaa tgaagaaact ggatttggaa aatgggaaga taaagtaatt aaaaatactt
    24841 ttgcatctat gggagtttat gaaactttaa agaacacaaa aactattgga ataattagtg
    24901 aagataaaga agcaaataca atagatatag ctacaccagt tggagtcgtg gcaggtctta
    24961 taccttcaac aaacccaaca tcaacagtaa tatacaaaac tataatatct ctaaaagcag
    25021 gaaatactat agttttctct ccacatccaa atgcaaaaaa ttgcatactt gaaacagtta
    25081 atataataag tgatgcagct ataaaagctg gagctccaga agattcaata ttatgtataa
    25141 ctaatccaag tatagttgga actaatgaac tgatgaaaca taaagataca aacttaatac
    25201 tagcaactgg aggagaagca atggttagag ctgcttactc ttcaggaaca ccagctatag
    25261 gagttggacc tggaaatgga cctgcattta tagataaatc agcaaatgtt aagttagcaa
    25321 tcaaaagaat aatagattct aaaacttttg ataatggtgt tatatgtgca tcagaacaat
    25381 ctatagtaat agaaaaatct atggaagaga ctgttttaaa agaacttaaa aatcaaggtg
    25441 catatgtttt aaatgaagaa gaaagtaaaa aattagcaaa atttatattg agagctaacg
    25501 gtactatgaa tccacaaata gttggtaaga gtgttgaggt aatagcaaat ttagcagact
    25561 taacaaatgt gcctaaaaat acaaaagttc tagttgcaag agaaaataag gttggccaca
    25621 atgtagccta ttcaagagaa aaacttacac caatactagc gttctatgtt gaagaaaatg
    25681 tagaagctat tatgaacaga tgtagagaaa tattattaaa tgaaggtgcc ggtcacacat
    25741 tctccatgca tgcaaatgat gaagaattgg taaaaagatt tgctcttaac atgccagtat
    25801 caagaatact tgtgaatact ccttcagcac ttggaggaat aggtgcatca acaaatcttg
    25861 taccagcact aacacttggt tgtggtgcaa taggtggaag ttcaacttca aacaatatag
    25921 gaccacttga tttaataaat gttaaaagag tagcttatgg aatcaaagaa atagaagaac
    25981 ttggaagaga taaatctcaa gttgaaaaat caatgtttga ctcaattgat aaagaagaat
    26041 taataaatct tcttgttcaa aaactagtca aagaactagg ataactaaaa taaacaatga
    26101 aacttatagc tatagctata aatttctaaa aatataaact ataaaattaa atttttggag
    26161 gataagatta tggcaagtgc aaacgcatta ggaatgatag aaactaaagg attagtagga
    26221 gcaatagaag cagcagatgc aatggttaaa gcagcaaatg tacaattagt aggaaaagag
    26281 caagtaggtg gaggattagt tactgtaatg gtaagaggag atgttggggc tgttaaagct
    26341 gctacagatg caggagctgc agctgctgag agagttggag aactaatatc agttcatgtt
    26401 ataccaagac cacactttga agtagatgct atattaccaa aagtatcagc tgagtaatat
    26461 aaaaataatt ttaaaattta aattttgatt gaaaaagagg ctatctcaaa aatgagtctt
    26521 actaataaac tcaatgtatt ttgaggtagt cttttttata catctaatag gagatgtgat
    26581 aaaatgggtg ttttaacaga aaacgaaata aagagaaaaa ttggaaaaaa caaaaataat
    26641 ataactgaat tttatataga aaaaggacaa ataataactc cttctgcaaa atcttattta
    26701 gctgagagaa gtattgaact taaatatgtt gataaacttt cagatgtaaa taatgagcct
    26761 aaagaagttg taaaggaagt agttaaagaa aaaacatata aatatactac tgtatttggt
    26821 gctaaattgg atgaaaaacc agaacacatg actcaattaa atggaaatct tttagttttt
    26881 aaagaccata aaagaataat attgagagga aaaatagatt ctcttgaatc agaaatacta
    26941 aaggcacaga tactttgtca gaaactagat atgccaaagc tcgttaagga attgcaagaa
    27001 gttttagact ttgtaagaaa tataatgaga tgtgaagttt tagaagaaaa actagaggac
    27061 tttaaacttt taggattaac tcctcaagaa cttagagaac aatctcacta tcctaaaaaa
    27121 tactttggta taggacatga gttcccaagt tatgaaatgg gagaagtagt agtagctata
    27181 aatagtataa gaagtaatac acgagaggtt gaacttgcag cctatgaagc atttaagggt
    27241 gagtatggaa atgttcatag agaagattta ataaaggcac ttaatagatt atcgtcagta
    27301 ttttggataa tgatatataa agttagaact aataagtata agtagttgga ggacacaatg
    27361 gagaatctat taaatgaaat agtggaagaa gtaataacta gagttaaaaa agaagcattt
    27421 atagaagttg aagcatcagg aagacacgtt cacttaagta gagaagatgt agataaatta
    27481 tttggtaaag gatatactct tacaaaacta aaagacctat ctcaacccgg tcaatatgct
    27541 tgtaaggaaa gagtcacaat aactggtcct aaaggaagta taaaaaatgt agttgtactt
    27601 ggaccatgta gaaatgaaac tcaggtagaa atatctttaa cagatggttt aactcttgga
    27661 ctaaaagctc ctataaaaca gagtggagac ttagaaggga ctttaagtat taaaatatca
    27721 acacaacatg gtgaagttga acttgataag ggattaatgg ttgctaagag acatatacac
    27781 atgactccta aagacgctga aaatttcaat gtatgtgata aagaaattgt tgaagccaaa
    27841 gtgatgggtc aaagaccttt aacatttgat gatgtagtaa taagagtgag tgacagtttt
    27901 aaaacttata tgcatataga ttatgatgaa gccaatgcat gtggttattc aaaagggact
    27961 gttgctaaaa taataaagaa agtataaatt taacctacta tataaattac ctctggggag
    28021 gatttaatat gaattatgat aatcttgtag atttaataat ggaagaaatc tataaaaaag
    28081 taaatagcaa tgaaataaaa atatctaata aacctaaagc tgtgattgta tttgaacaag
    28141 acaccaataa atttaactta ttaaaagatg aatttgaaat agtggaattt gataaaagta
    28201 taaaggaatg tgaaatagtg atagtttcaa gactttgtat gaggggatta tcgaatatag
    28261 cacttggaaa ttcaacaagt gatgaagaaa gatttatact aaaaatgatt atgagtggca
    28321 aaaaagtgta tgttttagat gaaggaattg aatacaaaaa atataaggat actgcaccaa
    28381 aagcattata taagaaattt atatcatttg aagatgaaat atgtaaattt ggtgtagaaa
    28441 ttataaaaga cttaaatgct ataactaaaa ataagttaaa cataaaaaga gaactagaaa
    28501 gtactatagg ttctaaaaaa gaagatacaa aagctttaga taaagatgtt ttaaatttaa
    28561 ccagtgtaga aagtgtaaaa atagataatg aatttagttt agatttaaga aatagaaaac
    28621 ttatatcgga agctgactta agaaaaccaa ctataaatgg agttaaaaac atactagtta
    28681 ataaaaaaag tataataaca ccattagctg tagattttat gagaatacac catctcaaac
    28741 taaagaaagt ataaggaggt aattttatgg atataggaaa agttgtaggt aatgtttggg
    28801 ccacaagaaa agatgaaaaa ttatgtggcc aaaaactttt agttgtaaaa attttaaaaa
    28861 ctaaaggcac atacaaggaa ggcttcatgg ttgcagccga taatgcagga gcaggaaatg
    28921 gagacttggt tcttatatcc agaggttcct cagctagaga gtcgattgaa aaagctcatg
    28981 ttccagtaga tgcaactata gttggagtag tcgattcgtt tgaggtgttt gatgaataaa
    29041 agtataggag ctatagaatt taaaagtatt gctaaaggta tagaagtatc caatgaaatg
    29101 ataaagaaat cttcagttga tgtattgtac ttaaaaagta tttgtccagg taaatttcta
    29161 atagtagtag gtggagaaac ttcttatgta aatgaatgtg tagattatgg aataaaactt
    29221 ggagaaggat atattgtaga taactttgta ataaatgcaa tttcacaaga aatattagat
    29281 ggatttaaaa ataagtatca aaagttagat aatatagtct ctataggtgt tgttgaaagt
    29341 ggtaaggtat gtgctggaat aaaaatgctt gataggactt taaaatcagg cgaattagta
    29401 ttagtaaaac ttcaattatc ttttgctata ggtggaaaat tagtatatat agtagcagga
    29461 gatttaagta gtttagaata tgcattaaaa gaaagtgaag atgtagtaag agaaaaagaa
    29521 gtaatatata agactgtaat accatcagta gacagtcaaa taataaaaag tctaataaaa
    29581 taatgggggg aattatgagt ataaacgaaa ttataatcta tgtaatggta atattcatgg
    29641 tgcttggagc tatagataaa tgtataggta acaaatttgg tcttggagag caatttgaag
    29701 aaggtataat ggcaatgggt tcacttgcag ttgcaatggt tggtgttata tgtttagcac
    29761 cagttcttgc tgatgtatta agaccaatcg tagtgccagt atttaatata cttggagctg
    29821 acccagctat gtttgctgga agtttattag ctaatgatat gggtggtgct ccacttgcac
    29881 ttgaacttgc aaaagaccct aatgctgggt tatttggtgg attaatagta ggtgctatga
    29941 tgggacctac aatagtattt ataataccag ttgcacttgg aataattgaa aaagaagacc
    30001 aaaaattctt agcaacagga atacttgcag gtataataac aatacctatt ggagcattcg
    30061 ttggtggatt agttgcagga tttgagataa tgatggttct tagaaactta gtaccaataa
    30121 taatatttgc agtagttata gcacttggat tattgaaatt tgaaaatgct atgataaaag
    30181 ggttcacata ctttggaaag ggtgtagtaa tagttataac tttaggattt gctgctgcta
    30241 tagttgaagc tttaacaggg atagttgtaa tacctggaat gaagccaata agtgaaggta
    30301 tagaaatagt tggagatata gcaatagttt tggcaggagc attcccacta gtgtttgtta
    30361 taacaaaggt atttaataaa ccattaatgg ctttaggaaa agttcttgga atgaatgatg
    30421 tgtcagcagc agggcttgtt gcaagtttag ctaactgtat accaatgttt ggtatgatga
    30481 aagatatgga caatagagga aagataataa atgtagcatt ctctgtatca gcggcattcg
    30541 tatttggaga ccacttagga tttacagcag gatttaattc taatatgata acaccaatga
    30601 tagttgctaa attagttggc ggtataacag cagtattatt ggctatggtt atcgcaaata
    30661 agacactaaa aaaggagaat gtataagatg gatatatcaa atatagataa aaatttaatt
    30721 gaaacattag taagacaaat aatagaagaa aaaataagtg gaactaagga cacagtagat
    30781 tttgttagaa ataaagatat tagtggaatt acttctataa agttaccaac tgtaaaagtt
    30841 agtgaatctg atagattaga tacaggaaat ccaagtgatg tagtttacac aaaggattta
    30901 tttacattgg aggaaagccc aagattaggt tgtggtatga tggaaatgaa agaaacaact
    30961 tttgattgga ctctaaacta tgatgaaata gattatgtaa tagatggaac tttagatata
    31021 ataatagatg gaagaaaggt ttctgcttct tcaggtgagt taatatttat accaaaagga
    31081 agtaagatac aattttctgt acctgattat gctagattta tatatgtaac atatccagca
    31141 gattgggcat ctcaaaatta acaagaacca aattaagtta ataataatca aataaatagt
    31201 ttaaaataaa aactcttatt aaacacacat atttaaaaag gctatgaatt ttaattcata
    31261 gcctttaatt atgaacaatg ttatacttta gtagtatttt ttctatattt actgggagac
    31321 atattatatt ttttgttaaa taatctaata aaatgctcta catttggata accaacattg
    31381 ttgctaatat cagcaatagg aatatttgta ttcattaaca aactttcagc tctttcaagt
    31441 ctaattcttt gtaataattg agtaaaatta caacctgcaa tttctttaat aattttagaa
    31501 caataaggta tagaaaagtg aaatttatta gcaagttctt ctaaggttat atcaacataa
    31561 ttatcttgga tataagtaag aatatttgtg tgatttaaag tacctttttt cgtcacatta
    31621 ggaacttcta tactatcttc atagtctcta agtaattttg caaaaaacac cattattaaa
    31681 tgattaagta tattattata atatctatct tgttcattat attctgaaag catctctaaa
    31741 atagagattt ctattgattt atcattattt gtatgaaaaa gtatgtaatc attctgtttg
    31801 tctttataaa tactatttaa aaagaaggat gaaagcaagt tgttgtttct taaaaaatca
    31861 aagaaagcat cctcaaaagt acttctacgt attaatacat tgataataat actatcatca
    31921 aatactccta tagaatgttt tactccaggt gaaactatac aaatatctcc ttctttcata
    31981 tgtacattat gatgattaat tacctgatag cacttacctg ataagacata aatcatttca
    32041 aagaatatat gctcatgcac aaattgaggt gtgtagcgat tatgttttat aagtataacg
    32101 ttatccttgc tgttacactc aaaataagtt tcatctttca taagttgagg aatcttttca
    32161 ttataaatat atggaataat tagattatta ttaactatgt aatcctcatc taagttatca
    32221 ataaatagtt ttagggattc tggattttgt tttgcaaaat aataattttt ataaaataac
    32281 tcagattcat tataaatata aagattttga aataatttat ttaaactcat aaaatctcct
    32341 tcatctctaa gattgtttaa atataaaata aaaatatcat aaatatgaaa ataaatcaat
    32401 taaattggtt aaaaacgaca atagttcaag cattttctaa aggatataat gatgttaagt
    32461 cattagaaat aataaaaaca acaaaataag gggggattat aaatgactac tttaaaagtt
    32521 gttgatgaaa agaatgtacc aggaatttgg cgtcaaagaa taggctatgg gtcatctgac
    32581 ctagcttgta acctaatttg gcaaatgata tcgttatatc ttttatattt ttacacagat
    32641 attatgggat taagtgctgt agcaataagt tttatgtttg ttgtaacaag ggtaattgat
    32701 ggaattacag atttattggt tggttattgt atagataaaa caaatactcg ttggggtaaa
    32761 tcaagaccgt atttcctatt tggtgcagta ccatttgcat tattcgcagt actagcattt
    32821 agcgttccag atatatcatt aagtggaaag ttaatttatg cttatgttac atatattgga
    32881 ttatctttaa cttatactat agtaaatatt ccaatggctt caatattacc aagtttaaca
    32941 gatgatacta atgagagaac agcattatca acatcaagaa aattctttgg atttttaggt
    33001 tcaacaatag taagttatag tgctttaact ttagtgggaa agtttggagg cactgatgaa
    33061 gctctagggt ttaaagtagt tatgatgcta tttgcattta taggatgtgc aatattctta
    33121 tttactttct caaatgtaag agaacgagtt gaaataaaat ctgaaaatgt aacattattt
    33181 caaactataa aatcattaaa agaaaataaa ccttggaaac tatttgcctt aaatatatta
    33241 ttcatgtgga ctggattctt tatacaatct agtgcattaa tatattactt ttcatacaat
    33301 gttggaagta agtcgttggc aacaacagtg gctacaatta tgtcaataat accaatactt
    33361 gcaaacttct tagtcccaat tctagctaaa agattaggaa aacgtaatct atacataact
    33421 tcagcagctg tacaatttat aggtctagga ataatactaa tagctaattt aaatataagt
    33481 ttaattatag caggttctat agtttctgcc tttggatatg gaataaaaga aagtatatac
    33541 ttctcaatgc aggctgaccc tgttgattat gggatttgga aaactgggat aaatacaact
    33601 ggaacattaa actcagtaaa tggattttta ggaaaatgtg cacaagctat atcaggcggt
    33661 ttaggtggag cactcctagc ttggggtgga tacatagcta aagcggaagt tcaaccagca
    33721 agtgcattag tagctattaa aataatgtat gtttatattc caatggcact tttaatatgc
    33781 tcaatgataa ctatgaaatt ttatgactta gataagcaat atcctaaaat caaagcagat
    33841 ttagatgcta gaaaaataag tgaggaataa ataataatga cacaatcaag gagaataaac
    33901 atgtctaata ttacaaatag tataaaagac ttcagaatgg aaattaatca agatttcata
    33961 gataaagcag aaaaactaaa gccaatcctt atagaaaaac taattaaacc taagcaaatt
    34021 gttaatatta aaatgggtaa aaatgattgg gaggttatag atacaaaatc aatagatgaa
    34081 atatctaata taagtttagg taaaggagag agcatttgta ttgactttgg aaatcaccaa
    34141 gtgggatatg taaattttaa aataaaacca ataggtagcc caccagatgc acctactcat
    34201 ttaagaatta aattgggaga aacattatgt gaaataggag aggatagttc aacttacaaa
    34261 ggaagcataa gtagtagttg gattcaagaa gagactatgc atatagatat tttacctgat
    34321 aaaattaata tgaaaagaag atatgcattt agatatttgg aaataaaggt attagataca
    34381 tctcctaaat ataaagtaat agtagaagat gtatcttgta attttgtatc gtcagtagat
    34441 atgtcagaga taaattatct atcaaatatt gatgatgact taattaaaat cgataaaata
    34501 gctttgaaaa ctatgcaaga ttgcatgcag actgtttttg aagatgggcc aaaacgagat
    34561 agacgccttt ggataggaga tttaagacta caagctataa cgaattatga aacttttaaa
    34621 aataatgatt tagtaaaaag atgtttatat cttttcgcag gattaactca aaatagaggc
    34681 caagtaggag catgtttatt tatagaacct aaattattag tggatgatac tgctttattt
    34741 gactattcct tattcttcat atcatgttta catgactact atgaagcaac taaggatatg
    34801 gaaattttaa atgaattatg gaaagttgca tacattcaag ctaagttagc tttagaaaga
    34861 gttggaatta atggtgttgt ttatgatagt gatgattggt ggtgtttctt agattggaaa
    34921 gaagggttaa ataaacaagc aggtgcacag ggagtattaa tatatgcttt aaaacaagct
    34981 cataaattag ctataatatt aggcgataat gaaaaaaaag aagagcttga gtatgaaata
    35041 gatagagtgg ttcaaggtgc taaaaatcat ctatgggatg aaaaacaagg attctttgta
    35101 agtggtagtg aaaagcaagt ttcttggata tctcaaatat ggtgtgttct tgctgatgta
    35161 tttgataaag aaacaaatac aaagatatta gataacttat tagataatcc acctgatatg
    35221 gatatagtta ctccatatgc atatcatcat ttagttgaat gtttaatatt aaataataga
    35281 aaagaaaaag ctcttgaatg tataagaggt tattggggtg aaatggttaa ggatggagct
    35341 gattgtttct gggagctata taatccaaat gataaatatg tatctcctta tggttcaagg
    35401 ataataaaca gctattgtca tgcctggagt tgtacacctt cttattttat aagaaaatat
    35461 tttggaagag atagtaaaga agtaacaagc aagtataaat gatatttttt tgtatcttaa
    35521 agagaaatca aactcattat ataaatttgt aatattatat aatgagttta ttaatttatt
    35581 acaaagcata gtctttgaaa actttatgat gagtttagaa aattttaaag gtgattattg
    35641 ttgataatct aaagttgcac ttttatagat atagcatcac caatatcatg tgtaaccaaa
    35701 atagtagact tattctcatt cttaataata ctataaacat catcacaaac tagtagtcta
    35761 gtctgataat caagagctga aaaaggttca tctaaaagta gaatatctgg atttacagaa
    35821 agtgttctaa taagcgcaac tctttgtctc atacctccag ataattcttt tggatacata
    35881 cttctaaaat cccataatcc ataggtcttt aaaaggcttt caactctatc taaagatttt
    35941 ttatcttttt tgccctgaat ttccaatcca atagttatat tatccattat atttctccat
    36001 tcaagcaaat tatctttttg aaacatatat ccaatatttc cagtaatctt tatatcacca
    36061 ctagttggtt ttaaaagatt agtaagaata tttaatattg tagatttacc acttccagaa
    36121 ggaccaagta aagttaatat ttctccttct ttcaagttaa aattgacatc ttttaatact
    36181 tcaagctcgc cttccttagt gtagaagttc atatttatat ttttaacttc tactatgttg
    36241 tcattcatta tgccaccccc tataactttt agctcgtata tattatgtta ttaacaatat
    36301 gacctatttg taccattttt cataaatata atataaatat tttgtttatt tacgtatttt
    36361 cttagtaact tgtacgtata aattatagat aaataaatta taaggtaggg gataaatttg
    36421 agtaacataa taacgaattt aatagagtca atatttacta atccaataac tatattgttt
    36481 ttacttgcaa taactgtgta ttctgttttt aaaataatag aaaataacag agtatattca
    36541 tttgtaagtt caaaattaga cgaaatcaat agagactata agacaagtga gttttataaa
    36601 aagataaggg atgactacta tacatatagt aaagaaaatc cttatgcaga cgtaaatata
    36661 acttcattta tagaggaagt tgtatctgat ttaaagcata ataatttacc attgttagaa
    36721 aagattagaa gtataaaaaa ttcatcttca ataagtatat tacttggagt tttaggtacg
    36781 tttgttggtc tttctacaat gcttttatgt gttgatacta aagacattat aaattcactt
    36841 ccttcaacta ttagtagtat gcaaactgct tttacaacta gtatatttgg agttgtattt
    36901 tctctaatta taggttactt tactaagata aaagattgtg aacatgtttt gatacaaata
    36961 atgttaaagt ctgaaaattt actaacatct gaaataactc attttaagtc agaaagaata
    37021 gatttaaaag tagaagaggt aaaaaataca ataaaacaaa taagcaagtc tatagaagct
    37081 attgaaaaat tcgataaaat atctaaagac ttaaatgact ttaatgatga atttattagt
    37141 ggtatagaag ctttaaaaag ccttttagaa ggttctcaga gttctattaa gacatttgac
    37201 cagagtgtaa gaaaattaga taagcaattt aatattttaa atataaagtt tgtaaagctt
    37261 tttgataaat atgataatca agataacata aataaagaga ttttatttga tataaaagaa
    37321 tcttcaaaaa atatatacaa tgccactgaa agtcagttca aaattagaga ttatataaaa
    37381 aatataaatg caggatttgc cctatatgaa agaagtgctc aagatttatt aactaaatta
    37441 atgactcatg aaagtaaaat atctcaaaac caaaaaatcc ttttagatga aaagtttacc
    37501 ttagatgact caataaaaaa tctttcaaat attattgaaa acttttctaa tgacctacaa
    37561 gttaaactgg atatgatgtt tgaaaattct ttagatattc aagataagtt agatgttatg
    37621 tttaataact cttttatgaa tgatgaagtt cctcttgata gtgaagaatt atttaatgat
    37681 gatgttaata atgtatttaa tccttttagt gaagaaattt atgagataga ggataaagaa
    37741 ataaaggtca taggtgagga tgagttaaat gaataataaa tatagaagaa ctgttaacag
    37801 agaatttgaa aagagtagct tttggccaac atttacagat ttattatcta ctgtattgat
    37861 ggttgtgatt cttatcttat ttagctcaga aagtatttca ggttctgttg aacaagattt
    37921 agctaagaat gtcaatactt ctgttgagga aacttttaaa aaaagtggaa tacctgtgaa
    37981 agtagataaa tctaatggtc aagtaacttt tggtgaaaga accatgtttg atatagatag
    38041 tgatgtttta aaaccagaag ctaaagagat gttaaaaatg ttcgttccaa agtacatgga
    38101 gactatttat aaagattatg gagactatat atccaaaata gttatagaag gtcatacaga
    38161 tgatgtggga agttatatat acaacttaga tttatctcaa agaagagcat atagtgttgc
    38221 taaatttata gtgggagatg aaataggtga ctataaatac aaagataaag tgactaagca
    38281 tattattgca ataggaagat caaaagctga actcattaaa aatggtgata atagcgtgaa
    38341 tagagatgca tctagaagag tagaactaaa atatgaaata aatattaatc aaaataaata
    38401 attaaatttt tataaaaaaa aagaaggcag ttggtgtgag ctttaagcct tctttaagga
    38461 aaaagtttat ttatttttgt tgatacttaa catattataa tttttagaat cagtttgcaa
    38521 tatattaaac gtaaatggtc gtttaaaatg cataactgga tactactgat ataaaatatt
    38581 tcattttata taatataaaa attatacagt gtcaattttc tatgttattg caccataatc
    38641 tattatttaa aatattatgt aaaaaaatat cataaaaacg catatcatgt tataattact
    38701 agagtattat gaatatggag gcgtagtttg tgatagaaag aaatataaaa aataaaaaaa
    38761 attctaaaat taaagctttg atacttttat ttatagtatc tatatcaatt tatttaactg
    38821 gttgtgctac atcagacaat ggaaataatc aatcaaataa taatgactct ttgtctagta
    38881 gtatatcaag tgataagaat gtaaaaattc attttattaa taccggaaat agtgatgcaa
    38941 tattgattca agatggtaaa acttttacat tgatagatgg gggagataat gatgatgaga
    39001 aattaatggt agattatcta aataatcaag gtgtaaaaga tattaaatat cttatagcta
    39061 cccattctca tgcagaccat ttaggtggac ttgattctgt tgtcaaaaat ttcaatatag
    39121 aaaatgtttt tgtatcgaat ggttcagcag aaacaaagag ttatagagac tttataaacg
    39181 ctttagcaag taaggattta tctccaagtg taccacttga aaataataaa ttctatttag
    39241 aagattctta ttttgaggtt ctaaatacaa atggaggaga tactactaat gaacaatctc
    39301 tagtccttgt atatactaat ggaaatgata aagttttatt tacaggtgat gctgaagaag
    39361 gtactgaaaa agaaatacta tctaaacttg ataaagtaga ccttttaaaa gtagctcatc
    39421 atggttctcg tagtagttca tctcaagagt ttttggataa agtaagccct gaatatgcgg
    39481 ttcttttagt aggcaagggt aactcatatg gtcatccaca tcaggagaca atgaataaat
    39541 taaaaaaaat gggagtaaaa gtacatagaa gtgatgagtg ttcagatata atatttgaat
    39601 caacaggtga tggagtattt acaagttgta aagatggaag ttacaataaa ggcgttagag
    39661 aagatggaaa ctctggaaaa tcaaacaata atacaagtaa aaatgattct tttaaaaata
    39721 aacaaaatac atctaattca gcggaaatag tgtattttac tccaaaaggg aagagttatc
    39781 actctacaaa aaattgtagt gggctttcaa gaagtaaaaa aatattatca ggcacaattg
    39841 cagaaagtaa gaaaaatgac ccatgtgata tatgttatgt aaaataataa aaaatcaacc
    39901 atttatatat aaagcttctg agctacataa aaaaataagc tataatcaat agataacaca
    39961 ttttatctat acgaatagct tattttttta tgtatttttt aatagctatt taataactct
    40021 aaatacacca gttacaatgc ctacaatttc aacttctgag tcattgagca taattggttc
    40081 cataaaatca ttctccggct gaagtcttat taaatttcct tctttaaaaa atctcttaac
    40141 tgtagcagat tcaccattta taagtgcaac tactatctga gaattaaagg ctgtattttt
    40201 tttgtctact acaacgtaat cttcatctaa aattcctgca ttaatcatac tttcgccttt
    40261 tacttttaat acaaaattgt tactgccctt tactaaactg gcagggaatg gaatgtattc
    40321 ctctatgttt tgttgagcta aaatgggttc tccagctgtt atttgaccta ctaaaggaag
    40381 ttctattatt tcttgattag ctccagaaac atcattcact ttactacgtt ctaaaacttc
    40441 aatagctctt ggtttagtag ggtcttttct tatgtatccc agtttttcaa gtttatttag
    40501 atgagagtgc acagttgaag tagatcttaa ccctacagca gtacatattt ctcttacagc
    40561 aggtggataa ccttttaata ttatttgaga ctttataaat tccaatatca atacttgctt
    40621 ttcagttaga tctaaataca taacatcact catttccaaa catattttgt ttttatttcc
    40681 atacacttta tatttttaat tataacataa tccatttata tctgcaaaca tttgttcctg
    40741 atttttaatc atcctcaatc cattcaaaat tcttgactat atcacgtttt acatttttct
    40801 tgtgagctgc ataaagttga gtagttgtga cattatcatg gtcaagtaag ttttgaacat
    40861 catatataga aaatcctgtt tggattagag aagtcgcagc tgttgccctt aatttatgag
    40921 gactatatcc attttctctc gtagtatcaa gtggaataga tgtatatttt tttactagtg
    40981 ttcttatagc ctttgctgta attctcttat tttgaagaga taaaaataaa gcatcttttt
    41041 cttcatcatt taatagttca tctcttgttc tttcattttg caaataatct tttattacat
    41101 gttcacaagt atggtttata ggcattaaaa cttcttttcc gcgttttcta tatattttaa
    41161 attcacctct tgaaaaatta aaagaggaga tattgagttc tctaagttca tttaatctaa
    41221 gtccatatgt aacaaataat gctagtatag ctttatcacg taacttagtt tttctccaat
    41281 ataccttttc tttttctgta agcccttcac ctgtttctac tgattcaagc atcttagcaa
    41341 cttcgtctat ctcaagacgc ttaatggcat ctggctgagg tttaggaagc tttattggat
    41401 tgaatccatc cgttatatta ttatctatct gagagttcct gtataagaat ttaaatagag
    41461 tagagatgga tgattttttc cttgccaaag ctctattgtt attttcaaaa atcaatgtgt
    41521 ttttttctgt atttttataa tatctactac aataatcacc caagaataaa tttatatctc
    41581 ttgattttat tgtattaaag tcatcttctg taatatcttt tatacattct gcatttgtta
    41641 attctttggt ttcaatcaaa tatgaacaaa aaaaattaat atcttctaaa taagcaagtc
    41701 gtgtagaaac tgcaacagag ccttttagat atataaaata atccttcata aatacaggaa
    41761 gtttattttc caaaagtaga catttttcta tgagttcatt ttccttgata acaatattat
    41821 caggtttatc tgatttatta tgtactttta taactttctt atcattattc aaaattaaac
    41881 ctcctaaaac taaaatataa atcttttata ttatttttta aatatttata ctgaatgagt
    41941 ataaatattt aatttaatca ttttttgcat ttttaagaga ttagcagtgc tttaatcgaa
    42001 attcttacta actattccct aaatccacat ttaaagacta gttgagtttg agtactcttt
    42061 ttttatttct caatatattt atagaaatat tttaaaatat attgagaaat tttttatgct
    42121 ctactaaaat ctttttttat ataatatctt tatatgtttt aacaaaacca aatattagta
    42181 aaatatgtat ttatttaact aaagttttta aatggactaa ccaagcttaa aatataggat
    42241 attataagag ttactattga aaaaataagc cctattgcca taaataaact tacaaatata
    42301 ttgtatttaa ctattaaact ggatatattt aagttatcaa atccaaataa gtatgtaatt
    42361 agacttattg caaaaataac tatgactata aaactcaaac catttaaact atttttcaaa
    42421 tcagcactac taagtgacat atgtgtagat atagaataca ttaaaaacat aaatataaaa
    42481 tactttaatg aatatacact aggtgttaac aacattattc ttataaaatt agaaatatcg
    42541 cctaaaataa tgtatataaa accacttatg tctaaattat taatcatact tacatataaa
    42601 tttaaatcta tattttgagt cactttcata taactatctg gcaataatat cttaaaaatt
    42661 aaaataatca ttactgttcc acctataata ggtgcaattc ctataaagaa atttcctata
    42721 ctttgataaa gattatcttt tttataacta tgacttacat atcctagtat accatcattt
    42781 ttactttcta ttggtctgaa aaacttaact gaatttattt tatgcataaa aatcaaacac
    42841 attatcaaat gactcaattc atgaacaaac gttcctatag ctccagttac aataattcca
    42901 atttttccaa aagatgaaaa gataaattta ttatttagac tttctgtaat gctaaaaatc
    42961 aatccaaata caataaatat tcctatgaaa caaaaaatat ttattatact tatttttaaa
    43021 atttcgatta tataaatcat aagttaaacc tcatgtaaaa gtatttaact actctacttc
    43081 atatccatta cagtttaaaa ttttacaagc attttctata tctttttctt ttactaatat
    43141 atagtctgta tcatatgtag aaattgcaaa tatgcttatt ttattatctg ctaacaaact
    43201 acttaactta gataaaattc ctacaagtga aaagtctaaa ggacctaata tcttaagtat
    43261 tctccactcc ttttctgact taacatcaga aggaatatta ttatttaagc atacaatact
    43321 taattcatca tctgttctag ttatagagta aaacctctct gtatctatcc atgttggtat
    43381 tttagtatca ttatttaatc tacatactgc atactcttct accaataatt ttaatttcat
    43441 aatgtatatt tcctccaatc ttatttgttt acttaagatt atacattaaa agttacataa
    43501 aataaaacag ataaagtaaa aaaggttcac tatagtgtcc tatttctata gccaaccttt
    43561 aaaacttaat taaattctaa taaagagata tattatctag gttcaattat aagtttaatg
    43621 gctgttttct tatcaccttc gatttctata tcagtaaatg cgggaatgca aactaaatcc
    43681 attccactag gtgcaacaaa acctcttgct attgcaattg attttatcgc ttgatttaga
    43741 gctccagctc ctatagcttg tatttctgca atgcctcgtt ctctcagtac tccagccaag
    43801 gctccagcta cagaattagg attagatttt gatgaaactt ttagtacttc catttcaaca
    43861 tctccttgtt aatttgttaa agtatccatt acctaaagta ctaaatcata attgccattt
    43921 actaattaca atcatcattt aaagtatact tttataaaaa tatacttcta taatcatttt
    43981 aagaaaacct ttattttttt taaccatttt ataatgaaaa aactacaaat ttctttatat
    44041 tctataagca ttttccaata tttctaaatt tagtatatct ttgagctata atttcctctt
    44101 tatccatgtc tttgtaatga tttaatcttt ctaaaatata agcttttatt tcttttgaaa
    44161 cagcctctac atctttttgt gctcctccaa gaggttcttt tataatctta tctattattt
    44221 ttaaatcata taaatcatta cttgtaagtt tcataacatc acaagcctct ttagctttag
    44281 acgaatcttt aaataggata ctagaaagtc cttctggaga aatcacagaa taaactgaat
    44341 gttctaacat acaaacgtca tttcctactc caatacccaa agctcctcca ctaccacctt
    44401 caccaattac aaaagtgatt actggaacag aaagtttact catttcaagt aagtttcttg
    44461 caatagcttc tccttgtcct ctttcttccg cttctagacc acaaaaagct cctgatgtat
    44521 cgataaacgt tattataggt ctattaaatt tttcagcttg tttcataagt cttaatgctt
    44581 ttctatatcc ctctggatga ggcattccaa aatttctttt tatattttct ttagtatctc
    44641 ttcctttttg gtgaccaact atagtaacat taaattttcc tatctgacca attcctccaa
    44701 ctatcgaagg gtcatcttta aaaagcctat caccatgaag ctctaaaaaa ttagaacaaa
    44761 tatgttctat gtattccaag gtcgtaggtc tttttatatc tctacttagc attacctttt
    44821 catatggtga taaatgtgaa aaagcatctt ctttaagctt ctccaatttc tcattaagtg
    44881 aatttatttt atcacttaaa tctatattat ttgccttaga aataattatt aattgtttaa
    44941 tatcattttc taagactttt attttttcac tattattttc aatcaaaaca gttcctcctt
    45001 tatgccctat ttcttgtgca tagcaagaat ttgatataat acttccttca tttttcttct
    45061 atctactatc atgtcaataa aacctttttc aagtaaaaac tcagaagttt gaaatccttc
    45121 aggaagtttt tgatttattg tttgttctat tactcttgga cctgcaaaac ctatcaaagt
    45181 atttggctca gaaattataa tatctccaag catagcaaaa ctagcagtta ctcctccagt
    45241 agtagggtca gttagaactg atatatatgg taatgatttt tcttcaagtt tagaaagcgc
    45301 ttgagaagtc tttgccatct gcataagaga taccatacct tcttgcattc tagctcctcc
    45361 cgaagcagaa caaataatga taggtaaatt attttcagca gcatactcta ttgaataagt
    45421 tattttttct ccaacaatag aacccatact tcccatcata aaatcaggat tcattacaca
    45481 aataactgtt ttaattccat ttattcttcc ataacctgtg acaacagctt ctgactcttt
    45541 tgttttttcc ttataagagt ctactttttc tttgtattta ggaaaattta gtggattttg
    45601 aaattctaca tcagaattaa actccataaa agttccttta tcaatcaata aatttattct
    45661 ttttcttgct cttaagccat aatgtcttga acattttgga catacaaatg aattttcttc
    45721 tatgtccttt ctaaatacat gactatcaca acctttgcaa taggtccaaa atttatcatc
    45781 tacactattc tttttaaagt tgtcatctaa agaaatcgta acatacttag attcttttga
    45841 tgataaaaat ttttttatca taatctattt actccttata atgtagcaaa ttctttcttc
    45901 ataaagacat cttctataaa tttggtatga tgagtatctt ctctaaactc ctcacttgtt
    45961 acaagtgcct tttgaaattc tacattcgta ttaatacctt ctacaataat ttcgtctaga
    46021 gctctatata ttctacttat acattcttct ctagtttcag cccagcatat taacttacct
    46081 atcatagaat catataaagg tggtatagta tatcctgcat atacaaaagt atcaaatcta
    46141 acaccaaaac ctccaggtaa atttaatgat tctatcttac ctggtgatgg agcaaaattc
    46201 tttgatgaat cttctgcatt tattctacat tcaatagcat gacctctaaa agtaatatct
    46261 tcttgtttaa aaggaatttt atccccatta gctatagata tttgaagttt tataaggtca
    46321 agatttgtta ccatctctgt aactggatgt tcaacttgta ttcttgtatt catctctata
    46381 aaataaaagt ttttatcttt gtcaactata aactcaatag tacctgcacc tatataacct
    46441 acacctttta ctatatctac tgcaatttta tgaagttttt gtctttcttc atctgaaagg
    46501 tatgggctta aggattcttc tattactttt tgatttcgcc tttgcataga acaatctcta
    46561 tcacctaaat gtattgcatt tgaatgttta tctccaaata cttgtacttc tatatgtcta
    46621 ggattttcta taaatttttc catatataaa tcactattag aaaatgctgc taaagcttct
    46681 gaacttgcca tatcaaaatt tgaaaaaagt tcttcttctt ttctaacgat tctcatacct
    46741 tttccaccgc ctccacttga ggcttttatc ataacaggat atccaatttc tcttgcaact
    46801 tctaaagctt cttccttagt tttcaaaaca gattctgaac caggaacaac agggatattt
    46861 aattccatca tagtttctct tgctctagat ttatctccca tcaaaatcat ttgttctctt
    46921 gttggaccta taaaaataat attgttctct tcacattgtt ttgcaaattc gggattctct
    46981 gataaaaatc caaagcctgg atgaatagca tcacacttta atttaagagc aaggtatatt
    47041 atattttcta tattattata actcttactt atattatttg gtcctataca aatagattca
    47101 tcagctatat atctatgaaa acaatctttg tctatttcag aatagatagc aacagttttt
    47161 atacctagtt ctttacatgt tctgatgatt ctaactgcta tatcgcctct atttgcaact
    47221 agtatttttt ttatcaactt aaatacctcc tactacaatg gttttatctt aaataaaggt
    47281 tgattatatt ctactagttc ttcattacta actaatactt caattatttc acctttaatt
    47341 tcacttgtta tctcattcat aagcttcatt gcttctaata tacataaagt gtcgccttct
    47401 tcaactacat cgccaacctt aacaaaatta tctgcatctg gacttggaga atcatagaat
    47461 gttcccatca aaggagctac cactactgat agattctcat tagatgtgac aggtgtatcg
    47521 tttacaactg gcttttctaa agaaagatcc actactgatt cttgttgtac acttaaaaca
    47581 ggtgaacttg tagcttgagc ttttttagat acttctaatc ttaaatcgct actttcaagt
    47641 tttacatatt ctaagttagt tgagtctatg gcctttaata attccttaat ttcattgatg
    47701 ttcattttgt tacccccttg tattattacc tggtgctaat attatatcac aaaaaacaaa
    47761 tttataaaag aaaaagtgct gactagacaa tcaacacatc aatatatctt ttaattttaa
    47821 attaacaacc agtaacttat atttgtttta attttccatt attaatataa attataagta
    47881 taaaatgaat aaaattcaat attttttgca aaatacaaaa gaatacaaat taatacctcg
    47941 ggaattttta agacaaatac caatattatg caatttagac ttcactttct ttcaaattag
    48001 tatcatttcc tttattctta cataggatat actttaattt agctattaaa acattactat
    48061 ataggttaaa agttattaaa atcgcaggaa ttataaagta aactctagca cctataaaac
    48121 caaaaactac tgtagtaagt attaatcttt tatttaaagt aaaaaaaggt atattaaaaa
    48181 tacttttgtc tgatgtttct ggagtataag aatatataac tccaaaaatc aaagtcaaca
    48241 tacaaagtgg aagtagtgta taacttgaaa ttattcccag aaatcctata ctttcaaagt
    48301 atttgctagc actatttgta taaacaaaca tgtatccatt taagtaggcg catatacatg
    48361 atataatgcc aaaagttccc cctaaggatt gagtgtacca attaaaaaat ttagattcca
    48421 tatacctcac ctcctaaaac tgtatatata atgatatgca tttaaataat gaaatatatc
    48481 tttatgtgct tatgaataaa tttttgttaa tttcattaat ttatgtttaa gaaatttgaa
    48541 gtatagtgta gtatatatta atgtagataa aattttatgg tacttatttt atagtgctta
    48601 atcaagctat attattatag atttaaaagt tgttcttagg gttttatatt ttgttgagct
    48661 gaaaaattta ttataaatga agggatgttt tcgctttggt agatacatta gaatttggtc
    48721 ttaaaatttt attttttata ttatcaataa tttggatggg taaaataatg attttaagaa
    48781 ctgataagca aatagtaata aatcctttgc ttattggtat atctgcagtc cttgtgatgt
    48841 tgcatacctc acagagtaac attgaatttt ttggattaga tgtccagtat ataagaatag
    48901 ttttgtatat aatatattca ctgataattt taataggaat atgggctact aacagaagaa
    48961 atggaatttt ttaaataatc tatttctata aaatttaaag gttgctagta acaaagcgct
    49021 aatattagtg ttctgttact agcaaccttt attttgatta tacacttaaa ttgaaaatag
    49081 aatgactaaa taagttgaca gattatttta cattgacagt aattagaact tcttgagatg
    49141 tatttaaatc atttttgtcg tttagtataa cttttactac tgcttgacct gttttattac
    49201 ctttgattat catatcctca catgaaagta cactcttatc acttacagat acaataaaat
    49261 ctaaatcttt tggaaggtta tcagtaactt cccagtattt ataatagcta tcaattttct
    49321 tcgtaattat ttttctcaaa tcaatacttt caccttttgc tatattaaca ttatgatatt
    49381 tagagtccag tttatactga ttatcttttg tatcgataaa gtttaaatcg caatttacat
    49441 ccacaccatt atgagaaaga gaatttacta cactgtcatc aatcaaataa ttattggcaa
    49501 gatttattga atccatatct tttaaactta aagcttcttt aggaatctct tttatattat
    49561 tgttccaaaa aataaaattg tctacatttt caagatatga tattcctttt aaatttgaaa
    49621 tgctctcacc agttgcataa aattctccat ctaaagcctt tatattgctt atagtcatct
    49681 catctgggtt tatatatctt tttacaactg ctcttaaatt tgcatcagga aaaatatctt
    49741 taagttgatt ttcgctcaaa accttatcat ttgaatttat tggacttaaa gctgctgcag
    49801 aaataataaa tggtattaaa ttagctaaat tcatagtacc ctcccacata atttttttat
    49861 tataataatt taatttctat gagagggttc tgtttccttg ttatatatgc ctactttcgt
    49921 acactttatt aatataaatt aaaataaatt tctactatta aacttataaa catattacta
    49981 gttacgtttt ttagcttcac atctaaatat tcgcatacct tgtgacataa atttgtcttc
    50041 atactctgtt gtaacattat tttcatactc actatttcct aaatcaagag aaatattctt
    50101 taatagccaa ttatttgcag caatttcatt taaactaaac tcgaataatt tttcattatc
    50161 tgttttaaag tgaatttcgc catcatcttc caaaacccta ttgtacattt ctaaaaatcc
    50221 agaatgagtg agtcttcttt tactccatct atttttaggc catgggtcac agaaatttat
    50281 ataaattctc gataattctt tagcttcaaa gtaatccaaa atattgctta catctcccca
    50341 taaaaatagt atattattca aattagaagc atctgctttt tcaacagcct ttaaaagaac
    50401 ttcttcctta agttccatgg caatataatt tatgtcaggg ttctgcttag ctaaagttgt
    50461 tataaactta ccttttccag tcccaaattc aacatgtatt ggattatcat ttctaaactt
    50521 taaattccac ttgcctttta atttgtctat atcgtctctt aaaacatatt ttgtataact
    50581 taaaagcttt tcatctgcac ctttttttcg tcttcttctc acaataattc tccttacata
    50641 taaaaaatta gtaaaataca tttttattat acattatctc accaaaaaat aaaaagaact
    50701 ctcttaaaat agaaatttat ttctataaag agagttctaa acttactaaa aacttaatct
    50761 tagtggcacc ctgaacaacc agagcatcct cctccacctt gatctttcat attttcagga
    50821 ataactctaa atccaaatcc tgtatcttct attattatat ctccatactg actatattca
    50881 tcagagctca ttacaaattg taattctcca acttcataag ttaagtcatc ttcttttttc
    50941 tcatctaaag ctaatccaaa agaaggacct ccacaaccaa cacctgcaaa gtatactctt
    51001 atattattag gtttatcttg attgtctttt aagatacttt ttaaagtatc gatagctgtt
    51061 tctggtaaag taattttcat caaatcattc cctttcaaat attttattaa aacaatatct
    51121 attatatacc catacaaggt acataatcaa ttagtttttg catattttac taaaacttct
    51181 acctaatatt acctaaggct ttaaaatatt ttatataata ttttattacc ttaaataaat
    51241 accctatcat aaacttagta aacaaataaa attattattc taaaaaatat aataatttta
    51301 tttgttgttt taatattata acacatttga taatgtccaa ttcatatatg caaaatttat
    51361 atactttaaa tgattatctc aaatacaata attagccctt atacaattaa accatctgaa
    51421 actgtaatag tacgactact acttttggct gcttctggtg agtgtgttac cataattata
    51481 gtttgtccat tgtccctgtt tattttatcc agtaaatcta ttatttctat ccctgtttta
    51541 ctatctaaat ttccagtagg ctcatcagca aataaaatct ctggttttcc aattaaagct
    51601 cgagctatag caacacgttg ttgctgacca ccagataact ctcgtggtgt atgtttacgt
    51661 ctatcagtta aaccaactat atataagatt tcatctaatt gatttttata atcttttaaa
    51721 tttttaccat ctaatagcaa aggaagcatt atattttcct ccacatttaa atttggtatt
    51781 aagttataaa attgaaatac gaatcctata tttctacgac gtattatgct cattttctca
    51841 tcattaaaat gtgatatatc agctccattc atatacactt ttccactcgt tggagtatct
    51901 aaaccaccta aaatatataa aagagtactt ttaccagaac cagattgacc catgatagaa
    51961 acaaattcac ctttcattac ttgtaaagac acctctttta acactcgagt tgttgtattt
    52021 ccaattttat attctttgat aatatttttt gcttctacag ctaaactatt atgtgtaatt
    52081 ttcatattaa cctccataat tattcaaact taatttcttc tatcagtttc attttcttcc
    52141 cttttataat aggcactatc gaacctatta aagttactat aattcccaat aacccaacaa
    52201 taataaatgt tttaaaatct aaatctggtt tcattgaaat ttttggtcct gcaactataa
    52261 agatagtttg aatctcaagt atagatatta caataccaat aacagctcca agtaaacctg
    52321 aagtaaaccc ttcaatcagt gtcactttta tattttgttt attacttagt cctatagatt
    52381 tatacatagc tatagaacgt cttttttgaa tataattaat cagtagatta ttaataatac
    52441 ctactgtagc aagaagaaaa atgaaatagg tcatcttatt cataggagac aaaaaactac
    52501 ttatagtatt taaagaatca ttataaaatt cttcaactgt acgactccaa ttatatgtat
    52561 ctccaaataa atcccttatc tgaatcataa cagcatctgg attgactgct gtatatacta
    52621 aaaaaccata attagtttta tcaaaatcat taactgcata atgtgatggt ataacagctt
    52681 ctacatcatt tgcacgagat ttaaaactac ctactatttt ataagaaaaa tcatacttat
    52741 ctttagatag agttattgta tctcctatag ataaccctac tttttttaga gtatcttcat
    52801 tcaaaataac agaacgttta tccttaaaag cttctgttac ttgttttttt atctcaaaat
    52861 ttgtataatt gattgcgaac atagagttat atagttctat attatctgta ccctctagtc
    52921 ttgataatgt tacaccatta ccagaaatct cattattcat aacataaaga ggtaatatgt
    52981 ttttaattcc atccatatgt ctaacatctt caataaactc ttcattcatc tttccatctg
    53041 caaaaccttg taattctgcg tcacgaaaca catctgttat ataagttttg acaaagttac
    53101 caacaacgct tattgcaata actgcagaaa tacttataaa tagtaaagtg atattctgta
    53161 ttatattttt gttatttttc atatttctag cagctaattt accttcattc cctaaaatat
    53221 ttttataaac aaactcaaaa actatagaca tgatatcagt aataagagga atcaacacaa
    53281 tagtagctac aattaatcct agtaatgaaa atccgccagc tagatacaat gtattttcag
    53341 gggatattct tggaagtaaa acagataaaa taaacattat acttcctata aaaagtatag
    53401 aacgatttga aacattcttt tcttctactg ttcctagtac aatatttttt attggcaaat
    53461 ggctagcttt tttaacaggt atatatgcac taaataaaga aacgattatt gctactataa
    53521 cagatataat cactccaatg ggtgatatta ctgttggaat tgatattcct tgttcgagag
    53581 aatttcctaa cccatgaagc attaaattta aaacaactac accaatagga atagcaatta
    53641 atcctcctat acttccgtat aatatacttt caagcatcaa tatatgagtt acagtttttt
    53701 cattggcacc aatacttcta aatgttccaa taaaaggaag acgttctaat gtaataacct
    53761 tataactgct gtatatgata aatatactaa gggttaatgc aaaaaaactt attaaaaaga
    53821 aaggcattat cttttgtcta gcatctgaaa ttatcttagt ttcatttata gtatttgata
    53881 ctgtatattt ttcagtagaa agttcttcgg ataatttatt tactagattt tctgtcattt
    53941 cttcttctga ctctataaga actcttgtat atccactgcc tttatttata atttttgata
    54001 gagtctcttt aggtagcagt gcattcacac ctcttgtatg cctcaaaaat actgtatcat
    54061 aagatgcaat atcactaact tgaaaagtat aagactttcc ataaatctgt aaagtaatag
    54121 aatcaccttt ttttatttta tattttgatg taaaacggtt tggaagaata attttatcac
    54181 cagaaaaatc agtaatacta tcgccatttt ctaatcgtgg cttgttgatt ttatttagtt
    54241 gacttaagtc tgctgctata agactaaatt cttcatagta tcccccctta ttataaatag
    54301 cagagctttc caatacacca acctttgatt ttatagcatt taaatcaggt atgtcttcta
    54361 aattggttaa tatatctgga tttttacttt ggacagatat agtcgctgta ccagacatac
    54421 cttttgccat ttttctttgt gcactttcat aagataatcc aatcgagaat gaaacaaaaa
    54481 gtaaaactgt tgataaaact atggacaata acataactgc tgttctaatt tttcgttctt
    54541 taatatttgt gaaaatatac tttaatataa ttttcaaatt tacaccttct tcctttatct
    54601 aagatatttc agtataatat ttttatactt taatccaaat tgaatctcta atagactcct
    54661 ccatactttt atcattctat ttataatatt tttaatcaaa tcacctcctt aaataaaaaa
    54721 gattgataaa ctactatata aatataataa tctatcaacc ttaatatatt ttttatttga
    54781 ccttaattaa ccttaattaa ataggaaaga tgatataaaa tgaactaccc aatccaagta
    54841 tactttcaac agatatattc cctccatgaa cttcaataat ttgctttgtt attgctagtc
    54901 ctaaaccagt tccttctatt tttgttttgc ttcctctata ataccgatta aacaaatttg
    54961 atgcctcttc tcttgacatc ccctttccat tatcagatat aatgatttca attctttcat
    55021 ttaatgttat atgtacacaa actttagtat ttttatctcc atatgtaaaa gcattgacaa
    55081 taagattact aaaagctcgt tttaatagtg tataatcaaa atcaaagtta atattatcta
    55141 tattactctt aaattcaact atatttgatt catattctgg ataatttaaa atatcaatgg
    55201 ataattcttt caagagtctt actaaatcat agttattttt atttaaaggg attattccat
    55261 tttttaattg ataggttaat tttaaatcgt ttataagtgt atttgtatat tctatgttct
    55321 ttaacatgat tgaagcatat ttatatactt tttcaggtga ataattaata ctactatctg
    55381 taagaagctc tgcataccct tttattggtg aaagtggagt ttttaaatca tgagttatat
    55441 ttgaaatcca ctcttctctc ataatatcag ttttattttg tatctcatca cttctatgaa
    55501 tttcttcatt taaaatattt aaactatcat atatatcagt aaaaacacct ttaatattaa
    55561 ctggaagata gcttcgtttt gaaatatcac taacagcaga tgtaatattt gatatgcact
    55621 ttgttaccca gtaaccataa gcaattccag aaagcaaaat tattaaaaat ataatcccta
    55681 tgattgaaaa tacaattgac ttaccaccta caaatttact tccatcaaaa aacatattca
    55741 ctttagatat atttaatgga aaatatataa tataaatata gtcattttta ttatttttaa
    55801 ttgcattaaa gtatacagtt ccattacttg aattattttg gttagctaat gttaataatt
    55861 cagaattaga ataataatct ttatgctctt ttggttctaa aaacccataa actctatttc
    55921 cactagaatc taaaatttgc aaccacaatt gattttctcg aagcttttct aatccagact
    55981 gttttacttg tggcttatta tctataaata cgatttgttc attaaagttt tctgtaaatt
    56041 ttttcggcca gtcactacga ataaattccc catttggttt ctgaatagta ataagtgata
    56101 agaaaatacc tattactgtc aggattaagc aaataaaaat cataaaaaaa ataatgtatg
    56161 aatgaaatac cgttttataa ctaggtttat gcatttaatc aactcttttc ttaaactttt
    56221 attttagttt gattgttgct tatataaaat agacaataat tattgacatg taaaaattta
    56281 tttaaaaata caactatcta cataaattat atttatataa ttatatgtta tcaagctgtc
    56341 cgttgtattt aataaatcct tttgataaca tataaaagta agataaaatt ttccattaaa
    56401 taccttataa ttatacacaa aatttctata tacgttaaac agtatagaga aatttttcat
    56461 agaaccatct ttatagggga tactttataa aagaattaaa aaattataat atataaaaaa
    56521 cttcatagga gtgtaacaac atcagtaaag atataaaaac actatataaa aattcaaaaa
    56581 tattaagaat aatgaaatac ttgaaattgc ttatatcaag aaattttata taatataaac
    56641 tggtcaaata tgttataata ttaaattgtg acaagttcat ggaggtgttt atatgaaaaa
    56701 acaaaagtcg ccaattttac ttgaaatgct tggactattt ttgggttgta tatcaatgag
    56761 tattggtata aatatgtttt taaaaccaca tacaattgct cctggaggac ttagtggtct
    56821 atcattagta ctaaacaagg ttacaggact tccagtatca gctatcatgt taattatagg
    56881 tgtcccatta gtgatacttg cttttagaat tatgggtaca aaaaattcat taaaaacttt
    56941 atttggaaca gttgtatttt cagctatagt ccaattaaca gatccattat caaagctaag
    57001 atttactaat gacttattat tgtcttctat tgcaggagga atcctagttg gtataggttt
    57061 aggaataatg tttaaatcag atgcttctac tggaggaaca gacttaattg cactcatact
    57121 tagtaagaag ttcccaggaa taaaagctac aaaattcatg tcatgcctag atggaatggt
    57181 tgttatatct tctggtatag taaatcgtag tttagaaact gcactttact ctggtatagc
    57241 actttgtgta ttaataaaaa tagcagatat gataatggaa ggatttgacc attcaaaagc
    57301 attttttatt atttctgatg agcctgaaag tttaagacaa gctataactg aagaacttga
    57361 tagaggtctt actattcttg atggtaaagg tggatacact agagaaaata aagaagttct
    57421 attagtcgta gtttctaaaa aacaagaact ttatctaaag agattagtta aaagaactga
    57481 ccctactgca tttgttattg ttacagatgt gcatgaagtt cttggagaag gatttaaaaa
    57541 tttagagaac taataaaaaa ttaatatttt aagtatatat actattttaa ttaaaatacg
    57601 atttattcaa agagagtgtc tcataaactt tttggttcat gagacactct cttttgtata
    57661 aaatcaaatg cattttcagt atttttacaa taaaaaacag gcttatctat attttgaggc
    57721 aaccacttta ttgaaatttt atttagaaaa caatcattat taaataacta gcataaatat
    57781 taaatgatta tatctattgt tttttcaatt catattgata acaaggaaca ttttttacag
    57841 tatttccagt atgaattttt ttgatatact ttcctgtaca tttaaatcct aataaatcta
    57901 atgattttgt agaattttgg ttttcttcat aggttattgc aattatttta tttaagttta
    57961 gttctctaaa tccatattgt attactcttt ttgttatctc agtagcaaaa tcatgccccc
    58021 aataacttgg atttatacat atacctattt ctgcttctaa tgctttagga tttatattat
    58081 taaaccccat attcccaata actttattgt cttttttata tactatagca aaatgtccaa
    58141 ttttcccttt tttataggga tttagaaaaa atgattttat aaactttctt gtatcttcta
    58201 aagatttatg ctcactaaat ggtaaatgtt ttactactat tttattttta taacagtcaa
    58261 aaaaatcttc gacatcatct aatgatgcag gtcttagtat acaatttcta gtttctaagg
    58321 ttttcatttg aggatattca gaatcagaca tttctaatcc ccctttatac attaatctaa
    58381 atatactgtt catatttaaa atacgatatt aattatataa atgttctcaa attaacctta
    58441 tttttatttt taataaaaac taattactat atgaatcttt caaatttacg aacttatctc
    58501 tatttttata ttaaattact tgtgaaatat gtattctaaa ttatatgtta ttagatatca
    58561 tgcttaaaaa ttctttggtt gctaaggata aagatatatc ttttaaatgg cagtaaccta
    58621 tatttctctt aggtattggc tcttttatat ctaatttaaa caatttccca ttttccaaat
    58681 aatctatgct aaattcttct ataacacaag atactcctag atttatatac gcaaattcta
    58741 aaagcaattc atgagaaccc aattctatat ccgggtttag ttttatacct tttgataaaa
    58801 aatattcatt tacataaagt cttgaatttg ctttattttc tagcattatt aaaggcaatg
    58861 tatttaattc ttctaatgat atttttctcc ctttgtattc tatgtaatca tttgcacaca
    58921 caaatatatc atgtatttca atacactcaa caatatttag tgtatcatct tctattggca
    58981 tgtttataat tgctatatct atattcccat ctttgagtaa agatataagc tctctactcg
    59041 ttctatttat tgtagataca tgtatatgtg gatacttctt atgaaaaatt tctaaatatt
    59101 ttaacaagaa aaaacgtgca gctgtatctc ctactcctat ttttagagaa ccatattcta
    59161 attttttaaa tttatttatt ctatcttctc ctgatgatat taactttaat gcagtagtga
    59221 catgttcact tagaattttc ccctctggag ttaattttac tcccttattg tttctataaa
    59281 ataataaagt atctaattgt tcttctagtt gctttattga ctgacttaca gctggctgtg
    59341 acataaacaa ttccttagca gcaagagaaa aactcttatt atttacaact gcattaaaaa
    59401 ccttataaag ttcaagtttt atattcatat ataattactc cttatgtcaa atattagtat
    59461 tatttatttt acttataatt atatttgaat tataatatac atggtactaa tatgacaata
    59521 ttaattcttt aggaggattt tagataatgg atagattagt tggaactgtt tcaagagggg
    59581 ttagagcacc tattataaga caaggagatg acttagttaa aatagttgtt gattctgttt
    59641 taaatgcatc aaaaagtgaa aactttgaag ttagagacaa agatgtaatt gccgttacag
    59701 aagctgttgt agctagagca cagggaaact atgctcatgt tgacaatatt gcaaaagatg
    59761 taaaagataa atttggagat gatactgttg gggttatatt cccaatttta agtagaaatc
    59821 gttttgctat atgtttaaaa ggaattgcaa aaggatgtag aaaagttgta ttaatgttaa
    59881 gctatccttc tgacgaagtt ggaaaccact taataagtat tgatgaactt gatgataagg
    59941 gaataaatcc ttggtcagat gttttaacag aagaaaaata cagagaacta tttggatata
    60001 ataaacatac atttactggt gtagattatg ttgattatta taagaattta atcaaggatt
    60061 gtggtgcaga ggtagaaata gtatttgcaa acaatccaaa aactattctt aactatacaa
    60121 caagtatttt aacttgtgat atacatacaa gacaaagaac aaagagaatt ttaagacaaa
    60181 atggagctaa aaaagtatat tcacttgatg atataatgac agcaagtgta gatggtagtg
    60241 gttataatga ccagtatgga cttttaggtt caaacaaagc tacagaagaa acagtaaaat
    60301 tattccctat aaattgtgat gaagttgtaa acaaaatcca aggtaatata aaagaaatca
    60361 cagggaaaga tgtagaagta atggtttatg gagatggagc ttttaaagac cctgtaggta
    60421 aaatatggga attagctgac ccagtagtat ctcctgcata tacaaaagga ttagaaggaa
    60481 ctccaaacga agtaaaatta aaatacttag cagataatga ttttgctgac ttatctggtg
    60541 atgaattgaa agaagcaatt tcaaaataca tagttgaaaa agataataaa tctgatgatt
    60601 taacaggaaa catggtttct caaggtacta ctccaagaag attaacagac cttataggtt
    60661 ctttagcaga tttaacatct ggaagtggag ataagggtac tcctattatt tacatacaag
    60721 gatatttcga taactataca aaatagtatg ttttaataag atttaaattt tttggattat
    60781 atatattaac ataaaaattt attaaaacct cttaatagat atgacttttc aagagttata
    60841 tctattaaga ggtttattta atgttcacag ataagatata tttaaataat ttaaacaaga
    60901 ttgtcagaaa tttatataat cttaaaaatt tatataactc taactcttat ttatttctga
    60961 tttatttctg aaataatatc actcttcaaa atttgtctta ctggaataat tacagcaact
    61021 atactaatag tgatatttaa aataatcata cctatgtata gaggtgcatt tattttaaga
    61081 attggattta tatataaata tacacgtttt accataaaat aaatcataaa ttgtccaata
    61141 acacttccaa ttaccattat aatacttgca tagaatccat ataaaaaccc ttctcttatc
    61201 atcataagtg aaaacttatt atctgtaata cccatagctc ttaaaattcc aaactcatgt
    61261 cttcttgaaa aaattaagta gcttactgta ttgattatat ggaataaact tattgcaaga
    61321 agtacaaata caataccata tataaataag agtttttgat ttaagtaggt attatttttt
    61381 tcaatagcaa tagtataatc tgttacgata catcttttta catcacttac aacacttttt
    61441 atgtcctcag acaattccac actattacta tcttctgtct tttttatact tactgaatta
    61501 taattttcga tattaaagtt atttttcatt tgtccattcg tcataactat atccatacca
    61561 taatcaccaa tgaaatatat gttatttgcc atcacacgtt ttacagtagc agcaactaca
    61621 aattcttttg ttgtataatc attcttattt tcttctttaa atttaacaat ttcacctgtt
    61681 ggtttcatta tctttggcac tttaactttt attgtatctc ctggatttat atcaactgca
    61741 tcatacatcc cggttccatc cataggtagt ctaactataa ccttattatt tttaaccata
    61801 tcatgggtat taatctcccc atctataata taagaattta acccttctaa catgccattg
    61861 ttataaccat aaatatttgt ttttaaaaga tagccgcctt cattttgctt tgtacaaata
    61921 ccatcaaaaa aagtctttat cctgtaatct ttttcaagag gtttaaagaa atttttccaa
    61981 aatagttgtt cttctttaat ttgcatagct ccaaataaat atcttactgg atagactttt
    62041 gatattccct caatattgtt taatcttgaa attttatctt ttggtatacc tacatcaaaa
    62101 tctgttgttt gcatagttat ttggtagtca gaatttaaac catcatcagc tttcattgta
    62161 agttcattat tgtttttagt aagctgtata gagtaactag aacatagaaa tataattcca
    62221 ccaagtgata atgaaaacaa aattccaaca aataatccct ttttttgagt catgtattta
    62281 tgagataata cttttgtcat gttagaatgt tttacacttt ctaatattct ctttttcgta
    62341 ttagtaatct taaagttttt catagattct atactagaat atttattcaa ctgatgtaca
    62401 acacgtacag aaattaaaat taacaataat aagataaata aaaatcctaa ataaatagat
    62461 ttttcactta taaaaaatgc tcctggaaca atatcactac tcaaaaatat atgtggaaat
    62521 tgttcatata ttgtagacgc tactccaata cctaggaagc aacctatagg aaatccaaca
    62581 ataaaaagta aaaataattc taaaaatagt agaaataaaa gttgtttatt attagcacct
    62641 aatacttcta aaaccccata ttgtgatatt ctctgaagta ttgaaacatg gaaaatacta
    62701 tatactgctg ctgcaccaaa cactccaaca agtaatataa ttgcatttgt atttaattct
    62761 aaatttttta agaactcaaa tatattatat ttttctatat tttttggtgg ttttactcca
    62821 aattcaactg aaagaggcca gtttatataa gctttttctt ttgatatgtt gaattttttc
    62881 ataaatttat aattttgctt tttaatattt ttattttcat catattttac ataaactata
    62941 taagaatcct tttctttagg ctttaaataa tcgtttacga atccctccat agcggtttct
    63001 gggtttgaaa gacttgataa aataccacat aacttataga ttttcccatc taaattgatt
    63061 tctgttccaa tttctttgtt tacatttaaa ttgtttagag aatatgtgtc aagtactatc
    63121 tctccatctt tactaggaag agttcctttt aataattttc tacctgtcat gtctaaatat
    63181 gaagaatcag catttaaaaa ttctataata aaaggttcat ctatctgatt tttaggtttt
    63241 gtaacaccaa gtctatctac agtgtatttc tttgattttt tattttcttt aattttatta
    63301 agttgttcct tatctacttt atagaaataa tgataatctc cactatcttc ccttatcttt
    63361 tcaattctac ttttgtctgc actatgaact aaagaaccaa ttcccgtcaa taatgctact
    63421 gatagtacta tgcttaaaac tatagatata gattgttttt tataatgctt tatatattga
    63481 attgaaaatt ttactagaga catcatagta cttcaccacc agtattcacc acaactccat
    63541 cttcaatatg gataattgag tcgcatactt gtgctatatt ttcattgtgt gttaccataa
    63601 gtatcgtttg atggaatttt gcactacttt cttttaataa acataccact tccattgtag
    63661 ttttactatc gagatttcct gttggttcat ctgctaatat aagtgcaggt ttatttgcta
    63721 aagctctagc aattgctacc ctctgttgtt gaccaccaga tagttcgctt ggaaatttta
    63781 aacgcttatc ccaaattccc aatgtcttca tcagcatctc aatatattca tggtctatat
    63841 ggtttccttt atctaatgta acaggaagag ctatattatc ataagtgttt aatactggca
    63901 ttaaactgta gttttgaaat ataaatccta tatttcttct tctaaatact gtcaaatctt
    63961 tttttcctat tttagatatg ttctttcctt taattattac atcacctgag gttggactat
    64021 ctaatccacc tataatattt aacaatgtgc tttttccaga accagaagtt ccaactatag
    64081 cagtaaatgt agctcgttca atttctatac ttactccgtt taaggctttt actttagtct
    64141 catcttttcc atagtgtttt actaaattat tcgtcactaa tatactcatt taatttctcc
    64201 tttcaataga tatatgttct ataaaatatt gtaagtgacg ataattacac tcatcctaca
    64261 aagttagttt aaactcttac aattctgtaa gaagatgcta aaacaacatc cacttcctag
    64321 tttagattct actataatgt ttccattttc tttttctaaa attaatcttg taagatatag
    64381 accaatccct gtgccatttt ggtttgccac atttttactt ctgtaaaatc ttttaaaaat
    64441 atcatttagt tctctactat caatacctat tccttcatct ttaatagtaa tcttcgtata
    64501 cagttccatt tttattacag aaatagtaat cgtgctatct gatggtgagt attttattgc
    64561 attttctaaa acatttacaa ttgcttctat gatccacttt ttattatgaa ctaactttat
    64621 atctgaaaat ggttcaagat ttacccttat atttttagct tctgctttat taaagatagt
    64681 actgatactc tgaataagag tatctttaat tagtagttct tctacttcaa attctataac
    64741 tccatcctct aatttggtca ttttaaatag ggattgtaac aaccagtcaa tcttaaaagt
    64801 ttcatttttc atcttttgta aaaactcttt cttctgtaat gtggaaatat ttatattctc
    64861 cagaagttca caataaatgg ttatatttga aagtggagtt tttaattgat gtgacatatt
    64921 tgatattaaa cccttaatcg cttctttttc taactttgac tgttctacct ctatttctat
    64981 catatcctta atttttttta cttggtgaga aatttttgac gctcttgtat ccttcgtatc
    65041 tggataagta acttctttac cttccaatat ttgatttaac attaaactta attcatcata
    65101 tcttttttga tttattttag tagatactat aaatataaca actgtacata ttataaaggc
    65161 taatataaac atcttattct acctcattcc ataaataacc cattccataa gctgttttta
    65221 tatattttgg attagatggg tcatcctcta cttttactct aagtcttctt atatttacag
    65281 acacaatatt ctcatcaaca taattttctt cgctgtccca aatatggtgt aaaatttgtt
    65341 cctttaataa tatttgacct ttattttcaa ttagataact tagaagctta tattctacag
    65401 agctaagttc caaacatact ttatttttat atacttttag tagcttttgg tccaatttta
    65461 ttccattgga atatattact ttattattcg atttttttct tattgctact ttgactcttg
    65521 cctttaatac agataaagaa aatggttttg taatataatc atcaagccct atttctaatc
    65581 cttttacttc atcaatttct gagtctcttg cagtaagcat tataattggt atatctgact
    65641 tttcccttat tagttgacat acatcaaatc catctccatc tggaagattg cagtctaaga
    65701 ttataaaatc tatattttta ctgttaaata tatttaatcc ttcttgtttt gtataagcct
    65761 taaatacatt aaatccatca ttctcaaatg cataaaaaag accttcattt aagtttatat
    65821 catcttcaat aattaataag ttcaatttta ctctccttta gattttttag ataaataatt
    65881 attttcttgc attgtcatac taaaaatatt ttgattttat ttatatcact aaaaagattg
    65941 tatctaaatt tgttttcaaa ataaaaacat tataatcaag catataatta tatattcccc
    66001 aatttaatta cacttaaatt gaaaatataa cgttgttctt atataattaa attatacaac
    66061 aataaagtta tattttttaa atatattttt actaggggga atagaattga aaagggttga
    66121 tgagagaaat actatgtttg caagagcaaa ttacaaaaaa gatagtactg cttataatga
    66181 ctattataag aaaaatcctg acaaaaaaga aattgatgat agtataagaa atagaccaaa
    66241 tttatgtagt gaaggaacaa tgacttacaa tgagttaaac tctccaatgg caagtagtgc
    66301 attcgatttt ttatctgata tcaaatcttt atgtgaagga aaagtttctg atactaaagt
    66361 agatgtagat gcaaagtcaa tgacaaaaaa aataaagggt cttgcaaagc agtatggagc
    66421 ttctgtcgtt ggtataacta aattaaaaga ctatcatatt tatacaaata ggggtagaca
    66481 tgaagaaaat tacggtgaag aagttaatct aactcataag tatgcaattg tatttggatg
    66541 tgagatggat aaagaaatga taaatagagc tccaatgata tgtgaagtta tagaaacatc
    66601 aaagtgctat gtggatgcat ctatagtcgg catgatttta agttactata taagaaattt
    66661 aggatatgat gctagaaatc atatggatgc taattattta gtaatgcctg tttttatagc
    66721 tcgtgatgct ggtttaggag atataggaag aaatgctata cttacaaata aagattatgg
    66781 ctctagactt agattaggtg ttgttactac agatattcct cttttggaag atgaatatgt
    66841 tgattttgga ctagaagatt tttgtaaggt ctgtaaaaaa tgctctttta actgcccttc
    66901 tcattcactt tctaatgata ttaaaattgg tgatgatgga aaatataatt gggtgattga
    66961 acatgagaca tgctatatta aatggagata tttaggtaca gattgtggta tgtgtatatc
    67021 tgcttgccca tttagccaaa acctcgaaac tataaagaat actacttcat ttaagggtaa
    67081 taatgagctt attcaaaaag ctttagatga gtatacttca aaatttggta aaagaatatt
    67141 tatacctgga aatccatctt ggttgaaata attttattta ataaagaatc tgtcttagaa
    67201 tttatcatag gacgggttct ttattaaata tataaacttt taaatacttt ttctcgttta
    67261 taacaattca gcaatgtttt tagtctataa ttgacattat aaaatattaa actaaaagga
    67321 gtaactgtat ggaaaaaata ttagtagtag aagatgattc tatattaaat aaaactctat
    67381 catataacct aattgaagat ggatatataa ttacttcaaa atttacagct aaatctgcaa
    67441 tgaagtctat ttttgaatgt gaatttgatt taataatttt ggatattaat ttgccagata
    67501 aaagtgggtt tgaattatgt aatgaaataa aggaaaatta caatatacca ataatttttt
    67561 tgactgctaa tgatatggaa tgtgatatga ttaaaggcta tgaacttgga gctttggatt
    67621 atataacaaa accatttaat atcaatgtat ttaaacagaa agttaaagct tttttaaatc
    67681 attttacaac aaaaacaaaa caagattact atagggatgg atatcttgaa attaactttt
    67741 ctgagttatc tgccaatata aatggaaatc aaattatatt tacaccatta gaatatcgta
    67801 ctttaaaact gcttactgaa aatcctaaaa atattttaac aaggaaagta cttttagaaa
    67861 aactctggga tatagatgct aactttgtag atgaacatac tttaacatct gttataagta
    67921 ggattagaag caaaattgaa aaagacaatc ttcagtatat taaaacggta tatggcatgg
    67981 gatatatgtg gttaggtgaa agaaatgaat tttaaaaaat tttcttgtag ttctatttat
    68041 ttaataattg ctattggtat aatttttaca gctattttat ttaatatctc aatttatata
    68101 ataactgatg atttaaaact agttactcta ttattaatat atacaatagt actttgtgga
    68161 tttatagcat taataatatt tttacttcat aaaaaaatag ttatattttg ttctaaaata
    68221 tgtcacactt tagatagtat gatgaatagt gaagacaata ttgaaattga attagaagaa
    68281 gaaactattt tatcacgtat caatcacaga ttaattagaa tgtatgaagt tattcaagaa
    68341 aatcgcaata gtattgctat agagaaagct gatttacaag aactagtttc tgatatatct
    68401 catcaaatta aaactcctat tgcaaattta aaaatgatta atactactct actaaatcaa
    68461 acatttaaaa cagaaattca aaatgatttt ttaatggata tggaaaacca attagataaa
    68521 ttagattttt taatgcaatc tatggtaaaa acctccagac tagagacagg tataatcaca
    68581 ctatctaaaa agaaaaattc aatttatgaa acaattgcta cagcacttag tggaattttg
    68641 tttgatgctg aaaaaaagaa tattgaagtt acagttgatt gtgacccaaa tttatatata
    68701 attcatgaca agaaatggac ttctgaagct atttttaata tattagataa tgctgtaaaa
    68761 tacacaaatt ctaatggtaa gatacgtgta actacagaat gttgggttat gtatacaaaa
    68821 atagatatta ttgataatgg aaaaggaata tcagaaagtc atcaagcaga aatctttaaa
    68881 agattttatc gtgaagaaga tgtacatgac atagaaggta ttggaatagg actctatctt
    68941 tcaagaaaaa ttatatctct tcaaggtggc tatattaaag ttacatcaga gattggaaaa
    69001 gggtcgactt tttctatctt cttacctaat aaataaattt ttaaatattt catttgtaat
    69061 gattctgcaa cattttggtt ttatactgta tttacaagat gttaaggagg tattattatg
    69121 agtattttac aagtaattaa tttaaagaaa tattatggac aaaattcaaa cattacaaaa
    69181 gctcttgata gtgtaactct atatattgaa aaaggcgaat ttatttctat tgtaggtaca
    69241 tctgggagtg gcaaatccac attgttaaat atgatgggag gattagataa tcctacatct
    69301 ggaaaggtta ttataaaggg taaggagtta tcgactatga ctgatgaaca gcttacaatc
    69361 tttagacgca gaaatatagg ttttatattt caaaattata atcttgttcc tttacttaat
    69421 gtatacgaaa atattatctt accaatagga ttggatggag agaccataga taaggatttt
    69481 ataaatgaaa ttataaatat gctttctctt gaagaaaaat tatatgatat gccaagtaat
    69541 ctttccggtg gtcaacagca acgtgttgct atagctagag cacttgtaac aaaaccagct
    69601 attatactag ctgatgaacc aacaggtaac cttgatagta gaactagttc agatgtactg
    69661 agtttactta aagttacaag taaaaaattc aaccaaacaa ttgtaatgat tacacacaat
    69721 aatgaaattg cacaactaac tgatagaatt attcgtattg aagatggaaa aattgttaac
    69781 taggaggtgt agtacatgtt tagaaataat aatcgcacat ttataagaaa aatagcttta
    69841 aatgatttaa aaattaataa gcttaaaaca tatctttcag gtatcattat aatgatttct
    69901 acatgtttat tattaacagt gaccttagtt tcatataatg cttccgtaga cttagttaat
    69961 gcatctccat atcatgctat atataaatct gtagatgaaa aaacaaaaaa tatactatat
    70021 caagataaaa actttagtag tgtaggagct tacaaattaa ttggaagtaa taaaaagaca
    70081 gattgtatta tgtctattgt ttatgcagat gatacagcaa ttaaacttat gaattttcag
    70141 ccattgaaag gcaacttgcc tacaaataaa aatgaaattg ctatttcaga aaaatattta
    70201 caggaatttg gtttagataa agatattgga gatagcatta aattaaatta ttatgatgat
    70261 attacgaata aagaagttca atgtgatttt attattattg gatttctaga aaattattat
    70321 caagataatg ccaagcagta ctatacagtc gtttcaaatg attattttaa gaatatagct
    70381 tctacacctt tacaaaataa aagtaatact tttgacgagt caatacctga tactgtagat
    70441 gtattagtta aactatcaga agaaaataca gagaaagatt cagcttcaat taagacacag
    70501 ttaaagaaaa ttgctttatc tttaggtatt aagaaatata atatatactt aaatgataac
    70561 tatattgaat caaatttaat tgatggtgag cagattatta cagttttagt agttggaata
    70621 gttgttctct tttctagtgt ttttgttata tatagtattt tttatatttc agttgttaat
    70681 tcagttcaga tgtatgctaa gttgaaatcg ttaggtatga cttcttttca gttaaaaaaa
    70741 attatttctc tacaaggaaa tattttgtca attattttta ttccattagg ggttatagct
    70801 tcttgtataa ttgcttacat aattcaacca ttggcatggc aaatgagggc tgatttattt
    70861 ataattttaa ttttatcact ggtgatgttt ttaactgtta gaatttcttt atttaaacca
    70921 actagaatta tttctaaaat atctgctatt gaagccatgc aatatacaga aactaaattt
    70981 agaaaaaaag taaaaaattt tagttatata aatataaaaa atctagcatt aaagaatatc
    71041 gagtcaaata gaaagaaaaa tttgattgca ttaatatcac taagcattag tggagtttta
    71101 tttatttcaa tcgctaatct tgctaattca atagatttca aaaaacaact atctcaacaa
    71161 tttgtctata acgaagatta tataattagc attaagagtg ataacttata taagcatatt
    71221 acagaaatcc aacaaaataa tccactaaca gattctctta agaatgaaat taaatctatt
    71281 catggagtaa aaaaattaat tgaatccaaa tcaattaaaa gcaatattat agaaccttgc
    71341 gtcaaagata gagatgaaaa acaatttatt actctaatta aaggtattac gcctgaactt
    71401 tcaaaatcac ttgaagaata tattgtaagt ggaaaaatag actatacaca tttagattca
    71461 gatagtttaa ttataaataa atatagaaca aaatcctata gattaaattt aaaagttgga
    71521 gatacagtta catttaatat ttttagtgga aatgatatta ttaaaaagaa aatgaaaata
    71581 atgggaatta ttgacaattc caatacagga ggtatgtttt ttgcttcaga caaaacttta
    71641 gaatctctaa caccatataa tacaaattta gatttttcta ttttaataga taaaaagcat
    71701 tctaaagaaa ttgaagaaaa gttgttaagt ataattcaga aaaattcaaa tttaatgctt
    71761 tattcatatg aagatgatta tagaatgatt actagagcat ttcaatatat aattatagct
    71821 tcatacattt ttgttggttt aatttcttgc tttggtatac taaatatgac caatacccta
    71881 ataaacagcg ttttaattag aaaaaaagag tttgccttac ttcaagccgt tggaatgaca
    71941 agaaagcaac tgcaaaatat gctttataga gaaggtctaa acataagtat caaagctata
    72001 tgtatttcaa gtatactagg ttattttggt tcaaatctac tttgcacttt tataaaagat
    72061 gtaattagat tagactttat taattttaaa ttttctatat ttactatttt aattttttca
    72121 ttcgtattaa ttggtataca agttttagtg actgaattac ttgtaagaaa tatagaaaaa
    72181 aaatcactta cagaacgctt acgttctcag taagaatgta tataaaaaat atccattttt
    72241 tatacaagtt ttaacataat tttttaaaag ctaaagggat aggaaatttt gactttacat
    72301 aattttctgt ccctctactt gtttttattt tatacagata tacttcctta tatctccaag
    72361 caacatcacc agagacataa acaagcatat tacttatttt ctaaatatgt caattgcatg
    72421 acttgtaacc cctactaaat cttcacgttc acaagtagca aggtgatatt ttaaatataa
    72481 cgcaaatgca tcatcattca tagagtctac tgcttcacgc atatataaag ccaaaccatc
    72541 tgatgcaaca taatgcagtc tagttacatt aaatacagac atcaaatcat caatgttttc
    72601 tttacgtaca agctcaaaca aatcctttgg ctcagactta gcagcaaatg tctgtgggtc
    72661 aatcaaacct ttttcaatgt attcagatac attaatattt cctctatgga acccctcgtc
    72721 aatgagacaa ccatcagata taacatatgc aacaaaaacc acaccaccag gttttgttac
    72781 acgaattgcc tcatgtaaag cttgttgctt atcttctttg ttataaagat gatatagtgg
    72841 tcctaacagt aacgtaatat catatttatt atctgggaaa atagataaat ccatagcatt
    72901 accctgaata atgcttatat tttcatttga ttgagtattt ttacggaaaa cctctatatt
    72961 atgttcgacc aattccactg cgtcaacatc atatccctga cgtgccagtg tgtgagaata
    73021 gcgaccagtt gcagcgccaa tttcaagcac acaatcacct gattttatgt acttattaat
    73081 gtaatgcata gtagtgagaa attccaccat tccatgtttt aatgcaagtc gactatcttc
    73141 atcataagta ttataaaagt caattaagta ttgttttgtt tccataattt cacctcctct
    73201 atattagtta ataaacatta aatagacaaa ttccaatctg gtttttcttg tcttataaaa
    73261 gctgttaata tatttttcaa cattttttca gcactatatc tatctaatgt taattttttt
    73321 gttgctgtta agacagccat gccatgagta taaagaaata aatctaaaaa tattactttt
    73381 gcacattcca actctattcc aatgctttcc gaaaaaagtc ttgccttttt ttcattgtca
    73441 atttctttat aaaaatcatt tgcctcttcc atcatcaaat ctaaatcatt tataaataac
    73501 aacttaaata aatgagtttc ttcttgagca aattcaatgt atgaaagcgg aagcagtaaa
    73561 taaggactta cacttttaga attactataa ttaacaacat acttattata gtattcatat
    73621 gcaaaagcaa gaaattcatt ttttaattca ttcatgtttt cataacaagt aaaaattggt
    73681 cgagtggaac actgtaattt acttgcaata ctcctcgcat ttacagcttc aaatcccact
    73741 tctcttgtaa tatccaagac tgtattcaaa atcatttctt ttgttatctt tactttaggt
    73801 ggcatatatg ttcacctctc cattaaattt ttaataaaat acatacgtta cataactata
    73861 gtaacatatc aaagaattat gtcaagaaaa atctttgcat ttttttgcaa ttcctaaaac
    73921 tgataaataa aacatgagtt gcaattaatc tattaataga taacagcaac tcacattttc
    73981 ctttaaatac tcttcttttt atctaatatt tcatatacac aatcttctat tgaattaata
    74041 tctttttctt ttcttttttt agaatcaatt aaaacgaaat acaatataaa acctacaaca
    74101 agtccccatg ttccgccttt agcagcaatt acacctccca taagtccaat caatcccttc
    74161 tctacacctg tatcacatag ctccattgat agctttgtac ataaatatcc ttgaactaaa
    74221 agtgttactg acaacgctaa tggtataaga ggtgtagcaa tctgcgcaat tggataaaaa
    74281 cagataaaaa ttgctgaaac ccatactaat gtacccatac cactaaaaat agactgcatt
    74341 gcttcctttc caaccttgta cctttgagca acacttcctg taagtgtcgc agctaatgga
    74401 ccgcacattg gtatatatgg agaaatgatt gccataaaaa tatttcttat cccacttata
    74461 acattagacc tatttgaatt gaaatctata tattcatctt ttctattttc actttcagaa
    74521 agtactaaat tttcacctgt tataaaatca ccaaatgcaa ttatgtatat catgaaggcc
    74581 attggtatcc cttgtataaa taaaattaag cttggaaaac ctattccaaa aggagatact
    74641 gtatttatca aatttttaaa atctactata taaactaaat tatcaaaact aaatctagga
    74701 atttctattt ctttactaaa tatacccact attaaactca ctaaaatagc tgatactaca
    74761 ccatattctc ctaaatgaaa taaaaattta ttcttaactt ttaaagtatc aagtctttca
    74821 gaaaacatta caaaacaagc aaccaaaatt cctactgtta tagatatggg ataagagtca
    74881 aatctccctt taggactaaa ctctgatatt atagtagata taccaacacc cattagtatt
    74941 ccacctttaa tagaatttgg tatcttacta actaattttc cagctacacc agttataccc
    75001 attaaaataa atatgattcc taaatctatt tgtaaagctg ttaatgcttg tattctttca
    75061 atacccatac tgaactttaa caaatatgca gttgtaagag ttatagaagc tgtaatccag
    75121 ccaggtacaa ctgggtctcc cataaaaaca tgcaagcagt ataatattga attaattata
    75181 gccatactcc atgctacttc atatggtaat cctaaaattt gtgtactaag accaattgtg
    75241 cctaaacttg tcatacttga tattatacct tgaatagctt ctggtttttc aaacctgtaa
    75301 tgtataaatg gaattcttat cttgaacatt ccaaatttta tatgaggttg ttcccttcta
    75361 gcgagttttt ccataacttc actccacctt tcaataactc ttataagttt acaactttat
    75421 aattgtttat aaattatcaa tgtcgttaaa attagtatat aacatgcaaa ttatttaaac
    75481 aataaattaa atttataaaa ttgatagatt ttgtgcatat atagaaatac ctcttcattt
    75541 ttagttattt aaatcacttg ataaaggttt tttataaaat tcaatagttc tattccatga
    75601 ttcaaactgt ccttttgaat ttccttctac agttccacct gaagaaaaaa tccccccact
    75661 catactcata cataaagtct tctttagagg cataatatat gaaattggta acggatgtcc
    75721 catattattg tatgttaata attctacgtt attttgtttt ttctaatttt ttttaaccat
    75781 ataatataga atcattacaa actttttctt agttctttat aatatataaa aatatttttg
    75841 ttagttttca atatttgata tatatttatt tctatataaa atctgttatt atatacatat
    75901 aatttaaaaa tttaaaataa ggggaattaa tatgtcaaat aatattaaaa taataaaaaa
    75961 agaaataaac tatttcttat taataaattt tttactgatt gcttttacat caatattttt
    76021 atttttgtca atatcaaaac caaataatag tgaacttata tcaagcttct ctatattatt
    76081 tatgtatatt cctgcatttt cagcaattgt tgttctaaaa aaagtttcta attacaagtt
    76141 tgattcaaca gtggataaat ttttaaagtt ttttgctata actacaattg tgagaatagt
    76201 aatatctata gctgaaacat ttttaatcta tagtagtatt atttcttcaa caatagatac
    76261 attaacatct gtttatcttt tagcagttgt tctttacaat gaatttcaat ttgaagtttt
    76321 aaatttatct ttaagtaaaa atttcaaaaa agttttaggc attctattaa tattcttgat
    76381 attaattata gttagaaata ttattgataa agaaggttta tcaattaatg ttgtaaataa
    76441 atttgtcaca gtatttataa atataattat aaatttatgt tttggtttta atttattttt
    76501 tggagaagaa tttggatgga gatactttct tcaacctaga ctacaaaaga tttatggcaa
    76561 aaaatttggt gtattaattt taggttttat atggggaatt tggcatttgc ctctttgtgt
    76621 cactttgtac agtcccgaaa ccccatttta ttgtgttatt tctcagatat catattgtac
    76681 ctttatagga atatttttag gctataccta tatgaagacc aaaaaccttt gggcgccaat
    76741 attaatccac ttagtaaata acactgtttc tattatactt ggaggaagta ttgagtctat
    76801 atttacatta gaatcactat tatggagtat tctagttaat gctatattat ttttaccatt
    76861 cttatttgct aaagagtaca aagctaataa ttatgatgaa agttctaact agtctacaaa
    76921 tacatgattc tttagacata gaagcttttt atatttcata acaaaaccct cctagtttta
    76981 gacagtttta cacattttaa ctgtctccta agaggggtct agttcatttt gagaatggtt
    77041 tttaatataa acgatttatt attaataagg atattttttt atttaaattt atataatcga
    77101 acatctaata tttaatgttt aataaaatta tgcatttgca aaagtatata tggcattaac
    77161 ccttgctaca tataaattct catcactaca tccaatatat ctagcatatt tttcaatctt
    77221 ttcctttgca ttttcaacat cattttcgtc gctctccatt aactcattta tataaatatc
    77281 cattaatgat gctttatatt ctcttatatc ataacctaaa aattcagtca atctctcaat
    77341 ttccttacta aaatctccat cttcttttac caaaaattcg tatacatctt ccctatatgg
    77401 atttaaagtt attatttgtt ttactacttt acattcgtca gccttcccaa taaaaccatc
    77461 tttataatta ttaaataagg cattagattt ttttatagat tcttcatcaa tataagaatg
    77521 tacctcagtt atacgatttt ctataagagc atctacaaca gcataatgaa ttttaaaaca
    77581 atcattgtat aaataattac tcattttctt tactgtcgat tctatttcta aaaaactagc
    77641 atgaccgttt tttttatttt tatttggtat aataaaggtt ttatttaaat tattaaaaag
    77701 tctcttaaaa tctaaatatt tttcacaata aacactttta aaggtatcga tatctatagt
    77761 tataattcca aaactcacta tagtctcaat gcctttctta aaagactctt ctatatattt
    77821 ttctcctaga cttaaacctc tatcagatat ttgctttaga ttttggaaac tatctaagca
    77881 atctctctca aagtttttag atatttctaa agcatataat ttaaatattt tccttatctt
    77941 attataatta ttttttgtat catcaaacct gataatagct ccatttacat caaaagtaat
    78001 cattgagttt taacctcccc attagtttca tcaataaaat aaatttaata taaactttat
    78061 aatcataata ttaaacttat ttatactata attattaatt tgatgataaa agctattttc
    78121 cttctaaata aaaaatttgt ctaaagtttc taaaaaattt agacaaatct taggttatta
    78181 ctttttaaat tattccaaat actccaaata atattggtat aaatatagct ggtaacaaat
    78241 tggctacttt tatattcgtc aatttaagta catttagacc aagacctata attaataaac
    78301 ttccagctgc tgtcatttct gtaactacag gatcacttaa aaatccattt aaaaatgatg
    78361 ctcccacaca tataatacct tcgtacaaaa atacagatat tgcagaaaac attacaccta
    78421 tacctaaaga agcagtaaat ataattgaag ctattccatc tataacagat tttacaaata
    78481 aagtatcatg acttcctgta agaccacttt ctaatgagcc aactactgcc atagctccta
    78541 tacagaataa taaactagat gatataaaac cctctgctat agaatctttt ttatttcctt
    78601 tagaaaattt actttgtaaa aaagcaccca acttatttac ccatttatca atatctatta
    78661 attctcctat caaagcacct acagctacgg atattattgt cactaatgtg ttttttcctt
    78721 ctagtgctcc tgatatacca atgtacaata cacatagggc aattccattc attatagtat
    78781 cgctcactct ttgaggtaat cctcctttta ttacaagacc tactatacat ccacctgcaa
    78841 ttgctagact atttgctatt actccaaaca ttttttctcc cctcgattag ctaattgaaa
    78901 tttatcctac tattaaaact taaacatcaa tactttgtat tggatatttt aaatattcca
    78961 aaaattcttc aaagcctttt ctagatatat tcacagtttt agtatttata ttaggatgaa
    79021 aatttaagta atcttcttta agtacatctt tatctatgta aagctcaact tttctttctg
    79081 tatcatttat taatgaaaaa ggatttacac ttccaggaag aagtttaagt acattgtata
    79141 gtctttcagg tgaagcaaat gataatctag agctccctat cttatcttta agtgaattta
    79201 aatcgacttg tttttctcct ttaactacaa taagataata cttatttccc ttagcatttc
    79261 ttaaaaataa atttttacat tggcatccct ttgttattcc atctaaaatt actaattgct
    79321 ctgctgtata tacagcttca tgttctacta catcatattc aacatttaat ttattcaaaa
    79381 tatcatatat tttagtttca ttcatgctcg cttcgttttc atctcgttct ttaataatct
    79441 tgttatttaa atcactcata ctttcttctc cttaaaccct ccatcatcat atcattgtga
    79501 gatattattc tactatagct attgctctta ctggagctcc gtcagcatca ttatacttaa
    79561 atggcgctgc tataaataga aatttttctg gaacattttc taaatttgta agattttcta
    79621 tgattatttt tcctttctca aataaaatat gatgcacttc aaatactgat gtgtcatatc
    79681 tatccactga taacatgtct attcctatcc cttttatatt agtattagct atataatttg
    79741 cagcttcttt tgttaatgta ggatagccta catagtactg ctttttatcc caaaactttg
    79801 accaacctga tttaaatatt ataaaatcac tattttttat ttcatcttca tattttttta
    79861 gatattctaa ctctatattc ttatttccct tttcaagctc caatacataa gctttcccaa
    79921 caaaattctc tatatccaac ttatctaggg tctcaccttt agtgtacata tgtcttggtg
    79981 aatccatatg agttccgttg tgagaaaata cactaattaa tgtttcttga taaccatttt
    80041 cttcaataat agctactttc ttgatatctg gtctattagg ctctgcatat acaggcatgt
    80101 cattatgtgt cacgtgagtt aaatcaaaaa ccttcatctt tatatacccc ctatgttttt
    80161 attttctatt atatacctaa attcatttta tttctatcag attttattcc attatatacc
    80221 atactagtat atatttttta taaacttcaa aggatttacc gaaaaatctt ggaaagaatt
    80281 atcagtaaat ataacatctt cacccaaaaa acgtttatac cttccctctt ctttctttaa
    80341 agtaattctc tgtttttgtg aatggttatt aaaaaccatt atcttaagtg gaggtttttt
    80401 tctattagtc tgaactcttt ttaacatgta ttttatgtgc atgtcagctt cgggaaatga
    80461 atatccacaa aatattaaaa ggtcagtatc tcttaaagtt ttttctgtct cattccaaac
    80521 attacttaag aatatattgg acatattctt aaaatacgtt ggtggcacta taataggttc
    80581 tgtcaattca ccacactcta aacattttgt ttcagaacta ttttcaataa gtttcataac
    80641 accaccttca tgtggtgtaa gagttacact attacaaata ggacaataaa gccaattcaa
    80701 tgacccatgt atcttatata atttgattaa tggctctttc ggttttctcc aatttaattc
    80761 ttctttaaaa tttgtaaact ccacaccata atcaagcata attggcaaat cattcttatc
    80821 tcttaagcca gtaactgtat tatctatatg tatatcataa tttgcactga taaaagtagt
    80881 atctaaaagc aaatcatttt tcaaaagatt ttcaactaaa agtttatgat atttattatc
    80941 tgttctaggt gtattatgaa ttgcctcagc cattagcagt attaaatatt gtcttaaaaa
    81001 acgtatacta tcacttctgt tattaagatt ttctagtcca aaatttctaa atgcttcttt
    81061 tctttgctct gctaagtcta aaagccctaa aacttcttca aaggtaggaa aatttgcatt
    81121 atctatatta tcttttacta tatcaatgtt aaacatctgt ttaaagaaaa tatacaattc
    81181 tctattcatt ttggtattat aattggtagg atttagtttt ttaaaatatt cactaaacag
    81241 ttcattttga ataggtagat tctctgctgc tgaagctcct gctcctaaaa atattgctat
    81301 tttcatatag ttcctcctaa tataaatatt actcctattt ttatatccgt taaatatcca
    81361 tatcatttgt tttatgatac aataataaag ctgtccctta ctagaaaaaa tcctattaca
    81421 agacagcctt atattatatt aaatctttaa taattcataa atagaaagag catatatctg
    81481 agcagccttt ataatatcct ctactattaa gtattcatta gcttggtgtt ctgtttctgg
    81541 ttttcctgga aaaatagctc caaatgcaac acaattgtct aaagctcttg cataagttgc
    81601 tcctccagat gaaagtggtg ttccatcaag accagtttct tcttcatata cttttctaag
    81661 tgtcttaaca agaattgtat cttctggaac atagattgaa tccaagaaat catattcttc
    81721 ataatttaaa ttgtatttat ccgtcatttt ctttaattct tttacaaaat catctttctt
    81781 gtatgttact ggaatcctta catctattcc tgcaaattct ttttcgctat caatagttac
    81841 tctacctata tttactgtta gtttacctga cacatcatcc ttgcaattag gaattatatt
    81901 gtttccatta gcatcttcac caataacttc tgctaaaaat ttaattatat tagaatctat
    81961 acctatatta ttaagagcta tacaaagtct ggccactgca tttataccag tatcactcgc
    82021 tgctgaatgg acacttttcc ctattataca gattttatta ccttcaacag tatactcaaa
    82081 atttaattta tcaagttctt tttttaattt atcagagtat tttccaatat agattgcttt
    82141 acctggaact gcatttagag cctttccaac tgataattct atatcgcttt tgctatcaca
    82201 agtcaaatga acttgtaaaa gacctttttc tgcatttgtt attgggaatc tagaatctgg
    82261 agtaaatcca tagtttggta tttcttcatt attttcttta tatttattta tacatctcca
    82321 aagattttct tcgtcagccc caaaaatgaa tcttattctc ttattaaaat ctacatttaa
    82381 atccataaga actttaactg cataaattgc tgatattgta ggtcctttat catcttgtgt
    82441 tcctcttcca tacaatttac catcttctac aataccttca aatggaggat aattccaact
    82501 ctctaaatca ccttctggaa ccacatcaac atgaccaagt atacctatca ttttttcacc
    82561 gtttcctatt tctgcatatc cataatatcc atctttgtat actgtcttaa aacctagaga
    82621 tttacataag tctaatatac ctcttaaagc tttatctaca ttttcaccaa atggacaatt
    82681 ttcagttgct tcagatataa cactaggtat ttttacgctt tcttgtattg aagaaatcat
    82741 ttcatcttgt agagaattta ctttttcttt aatttgctct ttcatattat cacccttcaa
    82801 ttttcatcat aatatactaa taaatatttt gaccttttta aaaaaaaata tgcttatttt
    82861 ttcagttttt ttataaattc aattgctttt aaagtcccca tttttgaatg gtcaaatgta
    82921 agtcctcctt ggaaataaac attataagga ggtcttattg gagcatcggc acttaattct
    82981 atagaagaac cttgtataaa tgctcctgct gccattatta cttcactttc gtatccaggc
    83041 atgtcccaag gaacaggttt cacataagaa tcaactggtg cagcttcttg tataccttca
    83101 caaaaactta ttacttcatc agcattatta agtctaatac attgaataat atcacttctt
    83161 aagtcatcgt attttggtaa tacatcataa cctaattttt caaaagctct tgaacaaaag
    83221 atagctccca ttacagcctg agatactatg taaggtgcta agaagaaacc ttgaagtaca
    83281 tttctagtag ttccaaaagt aaggccacac tcttttccta ttccaggaga agtcattcta
    83341 taagatataa gctcaattaa atcttttcta ccagctatat atccacctgt caatgcaaga
    83401 ccaccaccag gattttttat taaagaacca gccataacat ctgctccaac atcagtaggc
    83461 tctttggtat ctaaaaactc accataacaa ttatcaacca ttactatagc ttctggttta
    83521 acggacttta ttacctctat agcttctttt atatcactaa ttgaaagcga ttttctccaa
    83581 gaataccctt ttgacctttg tatcataaca agtttagttc tatcatttat tttgttttta
    83641 attccttcta aatctaagtt tccatcttct aaaaaatcta catcatcata tgtaacacca
    83701 tactctttca atgaaccttt ttcttctctt atacctataa ctccctctaa agtatcatat
    83761 ggtctaccag taacagataa aatttcatct cctggtctaa ctataccttg tatacataaa
    83821 gtaagtgcat gtgtaccatt tacaattatt ggtcttacaa gagcatcttc tgtattaaat
    83881 actttagaat aaatttcctc tattttttca cgaccaatat cattatatcc atatcctgta
    83941 gtccagttaa agtgcatatc acttagttta gattcttgca tagcttttaa aactttatat
    84001 tgattgtatt ctcttatttc ttttatttct tcaaactttc cttttatatc ttccattatt
    84061 tcttgagata gtttaaaagt atcatcatct atcccatagt agtctttcaa taattctttt
    84121 gtctcattaa gcattttatc acctgtctct ttattgtttt atttaaatat gtaaaggaga
    84181 ctattttact aaaacaaata aattatagtt tatcagttag tataagtctc ctctcaatta
    84241 tcttaaatta aattagttat ctatctgttg ttattattat tattttgatt ttgatttgtt
    84301 agattaatat actttccagg ttgtatagtt gatacagcat gtttataaat catgttttgt
    84361 tgtctattat ccccttctat taatattata taactatcaa acccctttac aagcccttta
    84421 acttgcactc cattgactaa gtatatagta acgggtatcc tttctttcct tgcattattt
    84481 aaaaacaaat cttgtaaatt taaaactgta tttttcatta gatttgtacc ctcccaagat
    84541 taaattgaac ttctaaaata ttcctacctt atattctata taagttatga caaattttca
    84601 atattaagtt gtatacttaa aaatttatat attattttat agaatcttta atatataaga
    84661 ttatttcatt ttttaattcg tctatatttt catattgctc taaatcaaac cactttgctg
    84721 ttttatatct tttaaaccat gttatctgac gttttgcata ccttctagaa tctcttttaa
    84781 ttatttcaat agcttcttca tatgtatatt ctccatccag atactttaat atctccttat
    84841 agcctatacc ttgcattgat atcatatctt ttttaaatcc catacttaaa agttttttta
    84901 cctcttcaac caatccattt ttaagcataa tatcaactct catatttatt ctttgatata
    84961 aatgttctct atctctattt agaactatta ttatcggttg atattcttca ttaaatttta
    85021 aatcattgga aaaatcattc attttcttgc cacttaggca aacttcaaga gctcttatga
    85081 cccttttagt attgttttta tggattctat tagcagattc ttcatcaagt tcttttagcc
    85141 tattatgcat gtaatctatt cccttttcag caagttgatt ttgaagttct tctcttaatt
    85201 cattattagc atcagactgt gcaaaatcca tattatatat taaagagttt aaataaagtc
    85261 ctgtgcctcc agttactaaa acacattttc ccttttcatt tatttcatat atatattttt
    85321 ttgctctttg ttgaaactct gaaactgaaa atggatagtc cggtttaact tcatctataa
    85381 ggtaatgctt tactccttgc atctctgcct ctgtaacttt tgcacttcca atatccatat
    85441 attcatatat ttgcatagaa tcagctgaaa ttatctctgc attcatatct tttgctaatt
    85501 ttattgacaa atctgttttt ccaacagcag ttggacctgt aagtattata agtggtattt
    85561 ttttcatagc attcctttcc atatatttta cataattctt ttaaacattt tctctatttc
    85621 tgtcttagat atttcaacca ttataggtct tccatgagga catgtaaatg gattctcaca
    85681 cttttctagc tgttccaata aactttttat ttcaatatca tatattttgt catttgcttt
    85741 tatagcagac ctacatgcca tagatgcaaa cctctctcct tttaaatcat aattacttgt
    85801 aatttcttct atattatcaa ttatttgaag tataaatttc tcagtttcag gcactccaaa
    85861 tatagtagga acacatctta ccattatatg attatttcca aatatctcta attcaaaacc
    85921 aaatttcata aataactcca aattattttc aatttgaagc atatctacat ttgatacttc
    85981 aataatcact gggtctaaaa gtatttgcat attaatatct tgtctataga acttctccat
    86041 atacctttca tacagtattc tttcatgtgc agcatgttgg tccaacaaat acatagaatc
    86101 gtttttgctc aaaattatat aggtattaaa tacaactcca attacagaat atccatataa
    86161 ggaaaacttg cgttttgagc tacacaagta ctcttcttca ctatccttaa tactatctcc
    86221 taagtaataa tttccttcat ttctaattcc atcaacttga aattcttctt gtatattgtc
    86281 atttgcactg tcttcactta ggtaattaat gttatttact tcatcttcac ttgcatttaa
    86341 gacttcactt actgattgaa attcatttat tggtttttca ctcgataaag ttacaacttc
    86401 aataacttca tccttacttt tagtggtatt actattttta ggagtagatt ctaataaatt
    86461 atcatttctt aatttataat ctgtactttt ttctctactg ttaatagcga ttctaggctg
    86521 tgttttttta tcactataag tagcatattt tccaataaga tttgagtgta ttaacttaac
    86581 ctttaaaaaa tctctaagtt ctatatacac ttcttgttct ttttcaaatt taatttcaag
    86641 tttattggga tgtatattta catctataca agatggatct acttctatat ttaagaaaca
    86701 aactgcatgt tttcctattg gaataataga tttataactt tctgttattg catctattat
    86761 tattttactt tttacaaacc ttttatttat atagatatgt tgtaggtttt tattagaacg
    86821 gtatatatta ttattaccta tgtatccatt cattttaaag tgattgcact taaattctac
    86881 atctattata ttctctgtta tttcttttcc atatatactt ctaatcgtat ttacaagctt
    86941 cccatctcct ggagtattta gcatctgctt attgttattt gtatatttaa attgaatgtt
    87001 tggattacct attgcaagtt tatttatcaa atcacttatg tttatagttt ctgcatgagt
    87061 agattttaaa aatttttgtc ttgctggtgt attaaagaaa atatctctta taatgattgt
    87121 agtcccatta gtagagccta tgggttcttt tgatattatt tttccacctt caacatatat
    87181 tttagttcct attatttcat ctttagtttt ggttgtcatt tctaattttg atacagctga
    87241 aatagatgcc aatgcttccc ctctaaaacc aagagagtat aaatcataca aatcatcaat
    87301 ttttttaatt ttactagtag catgtcttaa aaacgatttt tcaacttcac ttgaaggtat
    87361 tcccattcca ttatctgtaa tcttaattag actttttcct ccatcaatta tatctataga
    87421 aattttattt gcacctgcat caatggagtt ttcaataagt tcttttacta cagaagaagg
    87481 tctttctaca acttcacctg ctgctatctt atttatagtc aaatcatcta ggatgttaat
    87541 tatatttttc atttttacac ctctaagatt ttatttcttt tgcttttctt tgaagattat
    87601 aaagagagtt tatagcatct aatggagtca tatttaaaat atccagattt aaaatttctt
    87661 ctgatagtat gtctctattt acactatcaa aagatatttg agttaaggct acttccttta
    87721 cagaatcatc ttggttagtt ttctctttat catcattttg cttcattaaa gcaacttcat
    87781 catttaatac tttaaattta gaatttaatt tatcataatc cttttttata tgcttgtagt
    87841 cttttacgat aagttcatgt tctattttta gagattcata tttattctta aaattacttt
    87901 gatttacctt aactaattct tcgtctaaat tactattaat tatattatta ttttctttat
    87961 ctccatttat tgcaacactg ttgtaaacat gatttttttc caagtcttta agtatatatt
    88021 ttgctctttc tataacttcg tctggtaatt tagccaattt agcaacatat attccataac
    88081 tcttatctgc tccctgagga attatttttc ttaaaaatat tattccttcc ccatcttctt
    88141 tgactgctat tgaataattt ttgacctctt taaactcttc ttctaaatca gtaagttcat
    88201 gatagtgtgt tgcaaataat gtcttgcatc taatgttttt ttgaatatat tctactattg
    88261 accatgctaa acttatccca tcataggtac tagtcccacg acctatttca tctaatataa
    88321 ctaaacttct ctctgttgca ttttttaata taagggatac ttcgttcatc tctaccataa
    88381 atgtagattg accttgagat aaatcgtcac tagctccaac tcttgtaaat attctatcta
    88441 gtattggaat atcagcatac tctgctggta caaatgagcc tatatgtgcc ataagagcta
    88501 ttatagcagt ttgtctcata tatgttgatt tacccgacat attaggacca gttattatgt
    88561 taataatgtt ttctccacga tttaaataag tatcatttgg aacgaaattt tcctcaccta
    88621 ctatattttc gacaacagga tgtctaccat ttcttatatc aagtttatta ttttcattta
    88681 tcgctggttt aacatagtta tttatatgtg caaccgttgc aagagagaca aagacatcta
    88741 tattagctat agtcttagct actttttgta ttctatctat gtttttatat attgtatctc
    88801 ttatctctac aaatatctca tattctaaag atttaatctt ttcctctgca tgtagtatct
    88861 tttcttctat ttcctttaat tctggagtta tatatctttc tgcattacta agtgtttgtt
    88921 ttcttatata tgtctcatct agctttgcct gtttaaagtt agcttttgtt atttctatat
    88981 aatacccaaa aactttatta aaccctattt ttaatgattt aactcctgtt ttttctcttt
    89041 ctctgttttc tatctccttt acaagaaagg ctccattctt agaaatctct cttaattcct
    89101 taagttcatc actaaaatct gatttaatta tgtttccatc ttttatggtt attgtaggtt
    89161 cttctaaaat agcttcatct attaaattgt atatatcatc taatttatcc attcctgaaa
    89221 catactcttt taggattttt gcatttgata gatttatagt atcttttaaa ttaggtaact
    89281 tttctatcga attttttaag tgaattaact cttttggtgt tactctctca aatgctatct
    89341 ttccacatat tctttctata tcgtatatat ttttaagtat atcatttagg tcttctctta
    89401 atataaagtc atcttttatt tcttctatta catccaatct attttcaatt ttagatttgt
    89461 ttatcaaagg ttcttctaca tattttctta aaagtctacc tcccattgct gtagaagttt
    89521 tatcaagtac atgtaataat gaaccttttt tcttattccc tcttatagtt tgggtaagtt
    89581 ctaaattagt cctagtaaac atatctaaaa ccatatattc tgatgaattg tatatattta
    89641 tattattaat gttagatgtt atttgttttt gagtattgta tatataattc agaagaattg
    89701 ataagcttga ctttattaga cctttgtcat caaactttag tttttgtaga taaacatctg
    89761 gaaaatattc ttttaatata tttatgtcca aatagttatc gctaaaactt tcatttatgt
    89821 atatattact tacagtagct atatctctaa gcttttctat aaagtctaaa tcatttataa
    89881 ttatttcagt tggatggatt tttgcaattt cctcaattac cttatcttca tttaaacatg
    89941 ttgcattagt ttctcctgta cttatatcaa cataagttag acctatatta gtaccatcct
    90001 tatacaaaga taacaaataa ttattctttt tattttcaag taaatttcca tctaaaactg
    90061 ttccaggagt gatgactctt ataacctctc ttctaacaat tccttttgct gtagatgggt
    90121 cttccatttg ttcacctatt gctactttat atccattttc aactaatttt gatatatatg
    90181 aattggctga gtggaaagga acaccacaca taggagcacg ttcttctaaa ccacaagctt
    90241 ttcctgtcaa tgctatttca agagcttttg aagctactaa tgcatcttca aaaaacattt
    90301 cataaaaatc tcccagtcta aaaaacagta tacagtcttt atatctattt tttacttcaa
    90361 gatactgttt catcatagga gtcaatttat tcatatctat ttgcattatc aaacctcctt
    90421 cttttctaat taaatattat atcatagtag atgattatta ttaacacaat atataaaatt
    90481 ttgacgtata actaaaaaca atccaaaatg tatactcaca ttttggattg ctaagtttaa
    90541 tacttattaa ataaaaatat atataatttt acaataaaga tattatttct tttttaagtt
    90601 taatgatgtt ttcaaggtta tcttcattta aatttctact atctataaca aattctttct
    90661 ttactattga tggttttttt gaaataacat aaattctgtt tgatagcatt atagcttcgt
    90721 caatatcatg agttataaga agtattgttg aatttacttt tttcttaaca tctaaaagcc
    90781 atttttgcat agatgtttta gttaatgaat caagtgcgcc aaaaggctcg tctaaaagca
    90841 ttatgtcatt agaatttata aaagttctca agaaattagc tctctgtctc attcctccag
    90901 aaagttctga agggtattta tcttcatatc cacttaatcc aaatacctca aaataaggtt
    90961 ttaccattga cctagcttta ttcctttttt ctttttttaa aactagtggt agtgatacat
    91021 tatctattat agttttatat ggcaagagta aatctttttg atacatatag ctatatttac
    91081 catttatatt cactttgcca ctatcataat ctgtaagttt agttataata ttaaaaatag
    91141 tactttttcc acatccactt ggccctaata tagaaacaaa ttcaccttca taaacatcaa
    91201 tacttatatc ttttaaaact tcaatatctt tataagtttt tgatacattt tctatagata
    91261 cttttacttt tttattttgg taaaaattca tttgtgtaag catcacttgc cttcatatcc
    91321 ttatctatta atttatattc ttttaagaat gatgtatagt tgttccatac actatctttc
    91381 atttctcccc atcgtggtgc atcatctttg tatttgcttg ctaaatattc ttgactcttt
    91441 aaggctagtt tttcatctac ttcaggtgca tgttttacta aaatttttga tgcttcttct
    91501 ggatttttta ttgcatattc ataacctttt gttgtagctt ttaagaattt tttagcaagc
    91561 tctggattat ctttaagcac agtttcattc gaaattataa gtggtgtata ataatccaat
    91621 ctctcatcca aatcttttac tggtataaaa tttaagtcgt atccaattaa atcagcttta
    91681 actgcatccc aaccttcaaa tatccatgca aaatctacag ttttcatagc tgcaaagaaa
    91741 tcatcttgac cagtattgac tatttttaac ttattaaaat cagctccatt tttcttcata
    91801 actgctttaa aaacagcttc ttctgatgga gaaccccaac caccataagt ttttccttca
    91861 aaatctttag ctgttgttat attcttttct tttggtgatg caaatccaga agtattatgc
    91921 tgtataacag ctgctacagc ttttattgga agtgggtctt cactagtctt tgcataagta
    91981 acctgctctt gataacttat accaaagtca gcttttcctg ttgctactaa agtctcggct
    92041 ccactttcag gtggttgtac tatttcaaca tctaaacctt cttctttata ataaccttta
    92101 tcaagtgcta caaataatcc agtatgattt gtatttggtg tccaatcaag taccatagtt
    92161 acttttttgg aagaagcatt tttatcattg tttttatctt tattattatt tgaagagcat
    92221 ccagttattg ttgccaatgt aaaaacactt actaaaccta atattcctaa ttttttaaaa
    92281 ttcataattg cctccctcaa atacctttaa tctgttaatc tatgtcttat aacaattttt
    92341 tttacaaact gtacaattcc tacaaacatt aaactaaata taactactaa tatagtagat
    92401 gcaaatactt tatcaagtgc atatgcactt tttgacctaa gcatataaac accaagtcct
    92461 ttcgttccac ctagccattc tgcaacagtt gctgccatta cagcatacgt tgcagatatt
    92521 ttaagtccag aaaaaaactt atccattgcc ataggaaact taaggtgaat gaatgtatta
    92581 actttatttg agttcatagt cttaaataaa tttaaataat ctttatcaat attctcaata
    92641 ccatctacaa aacttattaa tataggaaaa aaacaagtaa gcattaccat caatactttt
    92701 ggcattgttc caaatccaaa ccatatcata aaaagtggtg ctataattat tgtaggtatc
    92761 atctgagtaa ccaacataat aggataaaga cattttttta ttattgatac aaaatccatc
    92821 aatattccga ttaccaatga tattataatt gcgactataa aaccaagtac tgcttctcct
    92881 atagtaacca cagaatgcat ggataaattt tgataatctt taaaaaacac attaattata
    92941 tctactggtg ttggtagtat atactgagga acttctaaaa ctcctaccac agattgccaa
    93001 agaataagta taaacaaaaa tgttgctatt ggatatatac tatctttgac tttatctatg
    93061 atttctaagt ttttcatcta tagttagacc tccagctttt tcatctactc tagctactgt
    93121 tatgactctt tcacatccaa gattaaaagg gattttatgt acctttttta ataattcaaa
    93181 aacttcatca aaatcacctt caacagtagt gctcattgct cctatttcac atttaagacc
    93241 acttttttca atttcagcaa tacaagcatc tactacttta tacatttctt cttcaccttt
    93301 atagggtctt agtggcatta ctgctatgtc tgcgattacc atttaaatca ctccttttaa
    93361 aataattaat acctactagg tatattttgt tttttattaa aaaatttttt ttactgaaaa
    93421 gatattatat ttaaataaaa gaaaagtctt atccaaaata ggataagact tatttttatc
    93481 ttaactggtc tccctacact ggcattatcc aaacaggttc aaagggtcga gataaaatct
    93541 cctctcagca cattagctcc ccgaaatata ttatatcttt tctacttgat tatactacac
    93601 ttatcatatt ttaacaaatt ttttatttat attagatatt ttatctgttt aaaaatatct
    93661 aatataaatt gcacattatt atatcaaata aattatctta aaacgataat ttctcagtat
    93721 ctcctaaaac tagattaacg taattttcta atttttgttt tactatttca agcatatttg
    93781 gatatatatc aattccatcc aaacattgtg ctaaattttt atttttgttc atttaagtta
    93841 caatcattac tgattaagca tagtttttat actacactca tctttatata caaaaattcc
    93901 ttcaataaat tccttaaaat tatattctaa ataagtgatt tcatagtcag attcttgatt
    93961 aatctctact acacagggtt cttcttgtgg ttcacaacca ctatagtaaa gaaatatcat
    94021 ttcgtgccca ccagaaatgg tattatatat gaccatacct atatagggtt aacacattct
    94081 actatccaaa aacgactgcc agcattgcta cataaggaat atgttttttc tgcgtcaatg
    94141 acatatagac tctctaagta gaaaatgtta gatgccattc gttttgtatg gtattatcaa
    94201 attttttttt agatttttat ttcttcttat ccttgtccat tattcctttt atgacatagt
    94261 atgcttcgtg agtgaataat tgtaaataaa taatattcat taagctaaaa atagacttct
    94321 atctggattt tcaatatata aaccttttag cagtattttc tgtgataata taaatattac
    94381 tcgtccttat aatcaaaatc ttcagcaatt ggccttttat ataatataat tattttattc
    94441 aatttatttt tgaaaaataa aatatttttt taatttttaa aatctttaat atgtagcttg
    94501 aaaaacaaaa cgttttccta tatgatggta atagtagaat aaaactaaat aggcaaaact
    94561 agagaaattt agtgacgcaa agctataggg actaagactt atgaaatgag ttatgtcagc
    94621 cagttgccaa agagatattt tctttttgtt tttatgaaag ttttttaggg ggatatatga
    94681 tatatgttta tggataaaat ggatagatgt acacatatac taactgcata tatatgcagt
    94741 tcacgcgatt actgcaattt tatagacaca caattaaatg attttatact agaatatgga
    94801 gagaatgtag tagaatcttg tttgcatcag gtgatggtat tggtaagcag atataattaa
    94861 agaaatttta ttttctagaa aacccttttt agttttatct acgttttata attcattaaa
    94921 aaactaatta aaataagctt cattatctat ttttcatgaa gtaaacagtt gagtttatct
    94981 catatactgt ttaccccaat tacataattc taataatata gattccaatg atttaccacg
    95041 tttagtagac aaatattcaa cttttggagg aatagtagga taagaaatcc tcttaataag
    95101 tccatcgctt tcaagatact ttaattcttg tgacagtatc ttatgactta tatgaacaac
    95161 ttcttttttt aattgactat aacgtattgg ctcttgtttt aaaatatgcc ataaaataat
    95221 tgccctccat ttacttccta tcacagtcat ggtaaaacca attgaacaat taaaatcttt
    95281 ttgtctttct tcaatatttg gaaattcttc aaaattatta tctatatcca tctcaatcct
    95341 ctctttcaaa atagtaagta tctaactaaa aagtgcattc ttttttaatg tactaatttg
    95401 taatataatc ttgattgtag catagaacct tacataatac tactttttta gatgtatatg
    95461 tttaaatttt aatatagata tatgttattt tattaatttt atttaaacag ataataataa
    95521 ataataattt atctcaagtt ttctatgtac ataaactaat ctaatgttta gaaaggatta
    95581 tataatatga ataaaaaatt tcgtctttat caagttgact catttacaaa agaaaaattt
    95641 acaggtaatc cagctggtgt aattacaaat gctgatggct tatctgaatc acaaatgcaa
    95701 aaaatagcaa gagaattaaa taattcagaa actgctttta ttttcaataa attggctaaa
    95761 aatcatcaag aaaattatga tgtacatatc agatttttta caccaactaa tgaggttcct
    95821 atatgtggtc atgctactat tgctgcccat tatgttagag cagtagaaaa ccaactcaat
    95881 aacaaaacag tatttcaaaa aactggtgct ggaatattac cagttgatat tataaaaaaa
    95941 gataatgatt atgaaataat tatgacacaa ggaaaaattg aagtatctcc accattacaa
    96001 caaacctatc aagaaagatt acttaatgca tttggtattt taaaggaaga tattcgtaca
    96061 gattgtccta ttgccatatc atctacagga cattcaaaag ttatgattgg aataaaggaa
    96121 ttatcaacat taaatagttt atctccaaat ttatatgaat tatcgaaaat aagtcaagaa
    96181 ataaaatgta atggatatta tatttttaca ttacatgata aagaaactct acaagttcat
    96241 ggaagaatgt ttgctcctgc aattggtatt tcagaagacc ctgttacagg aaatgctaat
    96301 ggacctttag gtgcgtacct tgtacattat aaagtaatac ctatacccaa cacagagttt
    96361 atatttgaag cagttcaagg agaagcaata aaacgtaaag gcaagatgtt agtaaaagta
    96421 attatttcag ataataagcc agttgaagta aaaataattg gaaaagctgt aattgcattc
    96481 tcaacaaaca tagaaattga attataggtt ccttctaagt aaatttttga actttttaat
    96541 actaatttaa taacaaacta atttatatac aatcaaatta atttttttat tat
//
LOCUS       DBGJFK010000007        92088 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.007, whole genome shotgun sequence.
ACCESSION   DBGJFK010000007 DBGJFK010000000
VERSION     DBGJFK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 92088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92088
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.007"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            110..301
                     /locus_tag="ACOIAP_000607"
     CDS             110..301
                     /locus_tag="ACOIAP_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HGZ2637520.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMISRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            456..1865
                     /locus_tag="ACOIAP_000608"
     CDS             456..1865
                     /locus_tag="ACOIAP_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGZ2637521.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKRGEVYKKLGYKDILENLYKM
                     DTTEILGTDNLHFPEGIIKNSQEKASKVFKSDYTYYLVNGSSCGIQSAIMSVCSPKSK
                     IIANRDCHQSVINGCILGDIDIEYVPCEISEDTNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKNMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPSFTQSSMIHIQGNRVNIDKILNMLRMTESSSPSYLLLSSLELAVDIYENKGK
                     GLMEELLNNIRTFKNNIDSNIKMYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTTKDFSSLETALNNVVKEEFKFTKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVYLNFIQVIDLEYI"
     gene            1986..2675
                     /locus_tag="ACOIAP_000609"
     CDS             1986..2675
                     /locus_tag="ACOIAP_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGZ2637522.1"
                     /translation="MKGKLIIIESGSDASGKATQTKILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIVIADRY
                     TTSNMVHQASKMDVCDREKYLNWLADYEFNLFKIPQPDCVVFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLQKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKSMER"
     gene            2678..3613
                     /locus_tag="ACOIAP_000610"
     CDS             2678..3613
                     /locus_tag="ACOIAP_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2637523.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHRDYKIYIINNAEK
                     MTLEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKSYLI
                     DTGIEEERAQLLATFSRGSIENALNLSQSSEFSVMREDVQQYIQIMLDKNIIEILNIP
                     NNMEKYRGKIITLLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDVKNKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3610..4503
                     /locus_tag="ACOIAP_000611"
     CDS             3610..4503
                     /locus_tag="ACOIAP_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HGZ2637524.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVFLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4581..5327
                     /locus_tag="ACOIAP_000612"
     CDS             4581..5327
                     /locus_tag="ACOIAP_000612"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGZ2637525.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSVKLNGLEERVEIINED
                     IKYIDKVLDVNGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     SRGKFLMIHRPTRLVDIITLGRKYRLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNEDIGEL"
     gene            5328..6161
                     /gene="rsmI"
                     /locus_tag="ACOIAP_000613"
     CDS             5328..6161
                     /gene="rsmI"
                     /locus_tag="ACOIAP_000613"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGZ2637526.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGEYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHKFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMFKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDELTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6184..6888
                     /locus_tag="ACOIAP_000614"
     CDS             6184..6888
                     /locus_tag="ACOIAP_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HGZ2637527.1"
                     /translation="MEIGKIIIESLKREDTHKTFIELDDKHELEKIIPKVSCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNNKDFFPIHLRKHVSNYLNTYIEEGINNLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGINLKLSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSEEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7076..7504)
                     /locus_tag="ACOIAP_000615"
     CDS             complement(7076..7504)
                     /locus_tag="ACOIAP_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HGZ2637528.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7541..8971)
                     /locus_tag="ACOIAP_000616"
     CDS             complement(7541..8971)
                     /locus_tag="ACOIAP_000616"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGZ2637529.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLKYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGICKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9103..9687
                     /locus_tag="ACOIAP_000617"
     CDS             9103..9687
                     /locus_tag="ACOIAP_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HGZ2637530.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTVIAIITCKFFQRRYR"
     gene            9703..10224
                     /locus_tag="ACOIAP_000618"
     CDS             9703..10224
                     /locus_tag="ACOIAP_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HGZ2637531.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10290..10537
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10621..12558
                     /gene="metG"
                     /locus_tag="ACOIAP_000619"
     CDS             10621..12558
                     /gene="metG"
                     /locus_tag="ACOIAP_000619"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGZ2637532.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDEAKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKILSCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12588..13358
                     /locus_tag="ACOIAP_000620"
     CDS             12588..13358
                     /locus_tag="ACOIAP_000620"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGZ2637533.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIDTSI
                     TAIELAKKYDFIYSAVGVHPHEVSKLDDTAIEILRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKSPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13696..13845
                     /locus_tag="ACOIAP_000621"
     CDS             13696..13845
                     /locus_tag="ACOIAP_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnG"
                     /protein_id="HGZ2637534.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMLKYTSNVSIIKEPKLATVME
                     ELMKM"
     gene            13911..14042
                     /locus_tag="ACOIAP_000622"
     CDS             13911..14042
                     /locus_tag="ACOIAP_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HGZ2637535.1"
                     /translation="MGYGIVAEKTNNLNKAVSLFTSSTIKVGIYDERSSVKENKKQI"
     gene            14129..14965
                     /locus_tag="ACOIAP_000623"
     CDS             14129..14965
                     /locus_tag="ACOIAP_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HGZ2637536.1"
                     /translation="MLTELHCHTNISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEAIVLGEHYGITIIPGIEISAYDYINRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLRYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            14966..15961
                     /locus_tag="ACOIAP_000624"
     CDS             14966..15961
                     /locus_tag="ACOIAP_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637537.1"
                     /translation="MSFLQVKNVCKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDRDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKKVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDNGINKIAIRPEDIKVEFNRDSKDKDIKEGEILDIE
                     FRGFNYRITVEYCSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            15979..17337
                     /locus_tag="ACOIAP_000625"
     CDS             15979..17337
                     /locus_tag="ACOIAP_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGZ2637538.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLASLLKNAFM
                     DTSGNFIGILNFSKYIENPSLIASFKNSIFVSIVSSLISLCLAFIYSYAITRTNIKFK
                     NFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKSRDRAFLIVCSLITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAVFGTIFVFFSAYMIEKVDKFPKLRQIAYFLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNIVHFYSVCFITSNSSLKMLDI
                     EV"
     gene            17418..17672
                     /locus_tag="ACOIAP_000626"
     CDS             17418..17672
                     /locus_tag="ACOIAP_000626"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637539.1"
                     /translation="MKKDNIKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEG
                     FPKKPLEQMIDNDLKSAAKNREDILNKWISKYDGKTEKES"
     gene            17864..18394
                     /gene="rnmV"
                     /locus_tag="ACOIAP_000627"
     CDS             17864..18394
                     /gene="rnmV"
                     /locus_tag="ACOIAP_000627"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGZ2637540.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQIDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREAFIDALKQI"
     gene            18565..19434
                     /gene="rsmA"
                     /locus_tag="ACOIAP_000628"
     CDS             18565..19434
                     /gene="rsmA"
                     /locus_tag="ACOIAP_000628"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGZ2637541.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITGGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLENTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EEIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            19500..20762
                     /locus_tag="ACOIAP_000629"
     CDS             19500..20762
                     /locus_tag="ACOIAP_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637542.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEELEEEDEEVEDNEESNRDEDIEEEEY
                     IIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSSNEEIEEFNNYKEIENYNRVKLQE
                     EYIDIECEEDEEEDEEEVFEVNREDDRFVSSKPTKSKKVQKEQNNIEKIKRVNGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            20913..22028
                     /locus_tag="ACOIAP_000630"
     CDS             20913..22028
                     /locus_tag="ACOIAP_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGZ2637543.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVV
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEVNGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            22214..23110
                     /locus_tag="ACOIAP_000631"
     CDS             22214..23110
                     /locus_tag="ACOIAP_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGZ2637544.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDEDLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            23180..23977
                     /locus_tag="ACOIAP_000632"
     CDS             23180..23977
                     /locus_tag="ACOIAP_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637545.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITYGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(24032..25384)
                     /gene="murC"
                     /locus_tag="ACOIAP_000633"
     CDS             complement(24032..25384)
                     /gene="murC"
                     /locus_tag="ACOIAP_000633"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGZ2637546.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYQGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            25603..26481
                     /gene="purR"
                     /locus_tag="ACOIAP_000634"
     CDS             25603..26481
                     /gene="purR"
                     /locus_tag="ACOIAP_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGZ2637547.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDIIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            26637..26915
                     /gene="spoVG"
                     /locus_tag="ACOIAP_000635"
     CDS             26637..26915
                     /gene="spoVG"
                     /locus_tag="ACOIAP_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HGZ2637548.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            27128..28507
                     /gene="glmU"
                     /locus_tag="ACOIAP_000636"
     CDS             27128..28507
                     /gene="glmU"
                     /locus_tag="ACOIAP_000636"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGZ2637549.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVIIGNDTIIYPG
                     VMLQGKTKIGSDCIIGMNTSITNSEIGDGTEVKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHNVPDGALAIARERQVIKEGWVEK
                     KNQKDNQSK"
     gene            28601..29551
                     /locus_tag="ACOIAP_000637"
     CDS             28601..29551
                     /locus_tag="ACOIAP_000637"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0002189 - ribose phosphate
                     diphosphokinase complex [Evidence IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGZ2637550.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      30390..30475
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            30636..31157
                     /locus_tag="ACOIAP_000638"
     CDS             30636..31157
                     /locus_tag="ACOIAP_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HGZ2637551.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSIKSAALSYYSDTNKIPVTPDGQTGLNVLETYMESLPDKADIGGEYKLIKVG
                     NKLVLQIGKDGEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGEQLKDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            31308..32984
                     /locus_tag="ACOIAP_000639"
     CDS             31308..32984
                     /locus_tag="ACOIAP_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HGZ2637552.1"
                     /translation="MAKKVRIGDKLVEKGYITEDQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            32996..34204
                     /locus_tag="ACOIAP_000640"
     CDS             32996..34204
                     /locus_tag="ACOIAP_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HGZ2637553.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTAFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTPIGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILVSAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISKQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            34219..35931
                     /locus_tag="ACOIAP_000641"
     CDS             34219..35931
                     /locus_tag="ACOIAP_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HGZ2637554.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHNKDKFYIKNLNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIIHEFDLILDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQLKAKQMKNILK
                     IAPVVILILAIPYLCLIFSNNLANKELENVNAEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGANNKADNSSSNKTTTDK
                     SSNNETKSNTKSDSNGDKTNNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSTYTFSMTLYLKEGV
                     LTNE"
     gene            35924..36832
                     /gene="pilO"
                     /locus_tag="ACOIAP_000642"
     CDS             35924..36832
                     /gene="pilO"
                     /locus_tag="ACOIAP_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HGZ2637555.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGVLIKVIILLSILSYGYFGLYPQ
                     YQKYIVTKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVREYEHFYGVSTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTSYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            36859..37425
                     /locus_tag="ACOIAP_000643"
     CDS             36859..37425
                     /locus_tag="ACOIAP_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HGZ2637556.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGSNYEYNIETPDNIVKYEVSIETKKN
                     TEVYSVTRIEKNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTDKSIYTVSIF
                     YNESVQEGHKNSNLNNKTYTFDVMSRIG"
     gene            37461..37988
                     /locus_tag="ACOIAP_000644"
     CDS             37461..37988
                     /locus_tag="ACOIAP_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HGZ2637557.1"
                     /translation="MSKKNSKRGFSLIEVLVAMAIMGIILFAFFNIINTNNKANIKND
                     TDINSLNYVQSEIENLREKIKSGEFDFDSLDKMEDGTVVYEKLIDKSKKIVYDKVLSE
                     GNVSLYDTPYEKITTIKDEDGNLIDKENITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            38009..39547
                     /locus_tag="ACOIAP_000645"
     CDS             38009..39547
                     /locus_tag="ACOIAP_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637558.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLMFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQQKSISRSKLRNISDE
                     DFNNQNEENLEVERLGYMNNINFYLNKASSDLEKASIELKKLYDLDMLDYRDIEYVDE
                     NIISHRNSILDICKNYTSGDISKINEYILDEDINSTTLVEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSYTYKALDKISLAMQNMIEYRHTFHIDEQKVEVSNGIPNSQQYYELIQ
                     NPIINSKEYSWNSKWDTLENLLETLPNQTQGFNSLRVHLRNNVRKFEELSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEVDKTEDITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDSKKNIIGLGVEENSNSKYKVEAIINFNLNIDTNIVGNYDIKDKILINHDISSY
                     KKVN"
     gene            39647..40729
                     /locus_tag="ACOIAP_000646"
     CDS             39647..40729
                     /locus_tag="ACOIAP_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HGZ2637559.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTP
                     EVTMQMAKDIAGESMFKVIKEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPENIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKSGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            40710..41492
                     /locus_tag="ACOIAP_000647"
     CDS             40710..41492
                     /locus_tag="ACOIAP_000647"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGZ2637560.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLISGRKCRYCYEKISSRYAIVELITGILFLIVFMLYGISTSTV
                     YYLVLVSLLIIITFIDIDHFIIPDEILIFGAIFAIIFNLLFKEIPVKDSIIGFFICGG
                     SVWLIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNSLLTALLSVYVGAVYGICVII
                     ISKTKGKEYNSIIPYGPFISVGALITILCGKQLLEFYFSMIT"
     gene            41774..42244
                     /locus_tag="ACOIAP_000648"
     CDS             41774..42244
                     /locus_tag="ACOIAP_000648"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: protein motif:HMM:NF013632.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HGZ2637561.1"
                     /translation="MVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFCNIVQ
                     FDYINHIFGLVIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFILA
                     FLFFIILYITKIFKDIDIKKQIPFTPFISLATILIMFTEYNIFNFYYSLLYKFI"
     gene            42258..42818
                     /gene="pth"
                     /locus_tag="ACOIAP_000649"
     CDS             42258..42818
                     /gene="pth"
                     /locus_tag="ACOIAP_000649"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGZ2637562.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEVGQDLADFVLSRFRKEESDNINE
                     ALEKAAYAIDSIIRENIDMSMNKYNG"
     gene            42835..46221
                     /gene="mfd"
                     /locus_tag="ACOIAP_000650"
     CDS             42835..46221
                     /gene="mfd"
                     /locus_tag="ACOIAP_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGZ2637563.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYIEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDNLDLERLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTTNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            46252..47247
                     /locus_tag="ACOIAP_000651"
     CDS             46252..47247
                     /locus_tag="ACOIAP_000651"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGZ2637564.1"
                     /translation="MKKVITLVIAMILVVSVTACNSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFTKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSAKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDASASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            47370..47909
                     /gene="spoVT"
                     /locus_tag="ACOIAP_000652"
     CDS             47370..47909
                     /gene="spoVT"
                     /locus_tag="ACOIAP_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HGZ2637565.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            48029..49642
                     /locus_tag="ACOIAP_000653"
     CDS             48029..49642
                     /locus_tag="ACOIAP_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGZ2637566.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNIMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLMFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICIGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            49749..51197
                     /gene="mazG"
                     /locus_tag="ACOIAP_000654"
     CDS             49749..51197
                     /gene="mazG"
                     /locus_tag="ACOIAP_000654"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HGZ2637567.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLKNSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEIVPSMSFVDAMFNYLAIDPSEGFKLVDAFEIDNSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEYYDYNQEVCIVNGAGVKDLENKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     EFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            51286..51564
                     /locus_tag="ACOIAP_000655"
     CDS             51286..51564
                     /locus_tag="ACOIAP_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGZ2637568.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            51636..51878
                     /locus_tag="ACOIAP_000656"
     CDS             51636..51878
                     /locus_tag="ACOIAP_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGZ2637569.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            51940..52194
                     /locus_tag="ACOIAP_000657"
     CDS             51940..52194
                     /locus_tag="ACOIAP_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HGZ2637570.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            52195..52728
                     /gene="yabQ"
                     /locus_tag="ACOIAP_000658"
     CDS             52195..52728
                     /gene="yabQ"
                     /locus_tag="ACOIAP_000658"
                     /inference="COORDINATES: protein motif:HMM:TIGR02893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0034301 - endospore formation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex biosynthesis protein YabQ"
                     /protein_id="HGZ2637571.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKSKN
                     KKKSKPKKKKNKTKKRV"
     gene            52734..53018
                     /locus_tag="ACOIAP_000659"
     CDS             52734..53018
                     /locus_tag="ACOIAP_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGZ2637572.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINALKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            53131..54051
                     /locus_tag="ACOIAP_000660"
     CDS             53131..54051
                     /locus_tag="ACOIAP_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HGZ2637573.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSNKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQDDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEELEAMSSFIYDEIDKTLNHIKYRGLKTLIGIGGTITSLSAMNQ
                     ELEVYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            54141..56513
                     /gene="spoIIE"
                     /locus_tag="ACOIAP_000661"
     CDS             54141..56513
                     /gene="spoIIE"
                     /locus_tag="ACOIAP_000661"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HGZ2637574.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISIGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAIYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            56864..58756
                     /gene="pepF"
                     /locus_tag="ACOIAP_000662"
     CDS             56864..58756
                     /gene="pepF"
                     /locus_tag="ACOIAP_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGZ2637575.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNGDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDEQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMSDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNGNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            58870..59835
                     /gene="galU"
                     /locus_tag="ACOIAP_000663"
     CDS             58870..59835
                     /gene="galU"
                     /locus_tag="ACOIAP_000663"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGZ2637576.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEIVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEIRELEIQK"
     gene            60335..61939
                     /gene="rho"
                     /locus_tag="ACOIAP_000664"
     CDS             60335..61939
                     /gene="rho"
                     /locus_tag="ACOIAP_000664"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HGZ2637577.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKINEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQENRNQRNDYNKTTSVNDCNKPSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            62092..62292
                     /gene="rpmE"
                     /locus_tag="ACOIAP_000665"
     CDS             62092..62292
                     /gene="rpmE"
                     /locus_tag="ACOIAP_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HGZ2637578.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            62437..63330
                     /locus_tag="ACOIAP_000666"
     CDS             62437..63330
                     /locus_tag="ACOIAP_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HGZ2637579.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            63348..64196
                     /gene="prmC"
                     /locus_tag="ACOIAP_000667"
     CDS             63348..64196
                     /gene="prmC"
                     /locus_tag="ACOIAP_000667"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGZ2637580.1"
                     /translation="MTIKDIIIKYSDILKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTEFIGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISEIALEIAKKNAITNEV
                     DEKIKYINSDLFTAISNSNIKFDIIVSNPPYIKKQDIETLHTQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKFGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            64240..65304
                     /gene="prfA"
                     /locus_tag="ACOIAP_000668"
     CDS             64240..65304
                     /gene="prfA"
                     /locus_tag="ACOIAP_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGZ2637581.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            65433..66113
                     /locus_tag="ACOIAP_000669"
     CDS             65433..66113
                     /locus_tag="ACOIAP_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HGZ2637582.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGISGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDMSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            66142..67182
                     /locus_tag="ACOIAP_000670"
     CDS             66142..67182
                     /locus_tag="ACOIAP_000670"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGZ2637583.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNIIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVAIKINDMIKSNREKGLKTGVMC
                     TSKNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKSVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            67199..67648
                     /locus_tag="ACOIAP_000671"
     CDS             67199..67648
                     /locus_tag="ACOIAP_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HGZ2637584.1"
                     /translation="MNILIVCTGNTCRSPMAEAILKKAIKESGRSVEEYSISSAGIST
                     ANGMSASENSIKALKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILLQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDSYRSTMREIVYSVNEIVKKI"
     gene            67665..68117
                     /gene="rpiB"
                     /locus_tag="ACOIAP_000672"
     CDS             67665..68117
                     /gene="rpiB"
                     /locus_tag="ACOIAP_000672"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HGZ2637585.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLEGKGIECVDYGTNNATDSVDYP
                     VYGEVVANSVINKDVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNNA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            68153..68782
                     /gene="upp"
                     /locus_tag="ACOIAP_000673"
     CDS             68153..68782
                     /gene="upp"
                     /locus_tag="ACOIAP_000673"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011971477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGZ2637586.1"
                     /translation="MSKVIETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            69082..69897
                     /gene="yqeB"
                     /locus_tag="ACOIAP_000674"
     CDS             69082..69897
                     /gene="yqeB"
                     /locus_tag="ACOIAP_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent molybdenum cofactor
                     biosynthesis protein YqeB"
                     /protein_id="HGZ2637587.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEDVECIFCNTEKEIEEALSQRKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRTITNGRAEKNTGVPG
                     AIKGFSKERVMHSQHDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGARVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            70123..70560
                     /locus_tag="ACOIAP_000675"
     CDS             70123..70560
                     /locus_tag="ACOIAP_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGZ2637588.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            70745..70972
                     /locus_tag="ACOIAP_000676"
     CDS             70745..70972
                     /locus_tag="ACOIAP_000676"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HGZ2637589.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            70977..71363
                     /locus_tag="ACOIAP_000677"
     CDS             70977..71363
                     /locus_tag="ACOIAP_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HGZ2637590.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAIRLFIMAVVLFASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            71366..72070
                     /gene="atpB"
                     /locus_tag="ACOIAP_000678"
     CDS             71366..72070
                     /gene="atpB"
                     /locus_tag="ACOIAP_000678"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000276 - mitochondrial
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_component: GO:0045264 - plasma membrane
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGZ2637591.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGQILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            72139..72399
                     /gene="atpE"
                     /locus_tag="ACOIAP_000679"
     CDS             72139..72399
                     /gene="atpE"
                     /locus_tag="ACOIAP_000679"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HGZ2637592.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            72522..73019
                     /gene="atpF"
                     /locus_tag="ACOIAP_000680"
     CDS             72522..73019
                     /gene="atpF"
                     /locus_tag="ACOIAP_000680"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGZ2637593.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKNDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQEKQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            73016..73561
                     /locus_tag="ACOIAP_000681"
     CDS             73016..73561
                     /locus_tag="ACOIAP_000681"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGZ2637594.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIAGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            73578..75080
                     /gene="atpA"
                     /locus_tag="ACOIAP_000682"
     CDS             73578..75080
                     /gene="atpA"
                     /locus_tag="ACOIAP_000682"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGZ2637595.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            75108..75986
                     /gene="atpG"
                     /locus_tag="ACOIAP_000683"
     CDS             75108..75986
                     /gene="atpG"
                     /locus_tag="ACOIAP_000683"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HGZ2637596.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIVKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMEVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            75999..77393
                     /gene="atpD"
                     /locus_tag="ACOIAP_000684"
     CDS             75999..77393
                     /gene="atpD"
                     /locus_tag="ACOIAP_000684"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGZ2637597.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVKKAKGSM"
     gene            77396..77656
                     /gene="atpC"
                     /locus_tag="ACOIAP_000685"
     CDS             77396..77656
                     /gene="atpC"
                     /locus_tag="ACOIAP_000685"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HGZ2637598.1"
                     /translation="MASEFSLKVVTPNNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFVNVTQDKTVILTESAEWI"
     gene            78109..78489
                     /gene="acpS"
                     /locus_tag="ACOIAP_000686"
     CDS             78109..78489
                     /gene="acpS"
                     /locus_tag="ACOIAP_000686"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGZ2637599.1"
                     /translation="MNIFDIGVDIIEIDRIRKAIEKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            78504..78965
                     /locus_tag="ACOIAP_000687"
     CDS             78504..78965
                     /locus_tag="ACOIAP_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGZ2637600.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            78986..79576
                     /gene="gerS"
                     /locus_tag="ACOIAP_000688"
     CDS             78986..79576
                     /gene="gerS"
                     /locus_tag="ACOIAP_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="germination lipoprotein GerS"
                     /protein_id="HGZ2637601.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDIVELPNTGKNNQYLFIGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            79591..80748
                     /gene="alr"
                     /locus_tag="ACOIAP_000689"
     CDS             79591..80748
                     /gene="alr"
                     /locus_tag="ACOIAP_000689"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGZ2637602.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKVCGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIVTIPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            80781..81068
                     /locus_tag="ACOIAP_000690"
     CDS             80781..81068
                     /locus_tag="ACOIAP_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HGZ2637603.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            81037..81420
                     /locus_tag="ACOIAP_000691"
     CDS             81037..81420
                     /locus_tag="ACOIAP_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGZ2637604.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            81591..82418
                     /locus_tag="ACOIAP_000692"
     CDS             81591..82418
                     /locus_tag="ACOIAP_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGZ2637605.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            82411..83352
                     /locus_tag="ACOIAP_000693"
     CDS             82411..83352
                     /locus_tag="ACOIAP_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGZ2637606.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKAF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNVIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIVKTVKEAIIAKRM"
     gene            83774..84868
                     /locus_tag="ACOIAP_000694"
     CDS             83774..84868
                     /locus_tag="ACOIAP_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637607.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDRLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPIIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDNHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            85094..85510
                     /locus_tag="ACOIAP_000695"
     CDS             85094..85510
                     /locus_tag="ACOIAP_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637608.1"
                     /translation="MDVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(85692..86261)
                     /locus_tag="ACOIAP_000696"
     CDS             complement(85692..86261)
                     /locus_tag="ACOIAP_000696"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGZ2637609.1"
                     /translation="MKKEFRKKVIESRKNKNANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLDFNNEVQTDNLIKKLLSLKKIVSSPITIKENRTLIPTQITDLKDGLRIGAYGIR
                     EPNEKSPKIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFNSIPKETHDAQLDYIVTETRIITPNN"
     gene            86415..87572
                     /locus_tag="ACOIAP_000697"
     CDS             86415..87572
                     /locus_tag="ACOIAP_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HGZ2637610.1"
                     /translation="MYLVISKKKAIFLGVILIIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGASKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIVEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTGAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            complement(87754..88908)
                     /gene="nagA"
                     /locus_tag="ACOIAP_000698"
     CDS             complement(87754..88908)
                     /gene="nagA"
                     /locus_tag="ACOIAP_000698"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGZ2637611.1"
                     /translation="MKSFIYADKFFMKHGTKEKGYLSIINGKFGEFQQERPSTTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNKVEGAKIQGIYLEGPFFTEKYKGAQNEKYFQDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTKYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAIKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLSSGSLAGSVLTMDRAVRNMVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDKGFNIHETYINGICKYKVNK"
     gene            complement(88991..89716)
                     /locus_tag="ACOIAP_000699"
     CDS             complement(88991..89716)
                     /locus_tag="ACOIAP_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2637612.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPSTK
                     VLSFEVVESTKYFSEKLGITPGEKIIKIMRLRLANDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEVIKVADEEFSAGIISDKEATLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            89986..90915
                     /gene="pfkB"
                     /locus_tag="ACOIAP_000700"
     CDS             89986..90915
                     /gene="pfkB"
                     /locus_tag="ACOIAP_000700"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGZ2637613.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAIGFLGGFNGEFIKNELKKLEIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESRDEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNKDSVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLREIDKYQDLVEVKKLS"
     gene            complement(91044..91961)
                     /locus_tag="ACOIAP_000701"
     CDS             complement(91044..91961)
                     /locus_tag="ACOIAP_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGZ2637614.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVNQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKHFSINTSMHRDSG
                     TKLEQVEILSKGRIQRIKNLNVLEIEEGGNLILKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECVKAQRLLEKIINSVK"
BASE COUNT        36696 a        10064 c        16683 g        28645 t
ORIGIN      
        1 attttttgtc aaaaaaaaca aaaaatacgt atttcttttt tcatttcggg aaaactaaac
       61 acaggaatta tggactttat aaaaatttaa ttctcgagga gtgatataag tgaaaaaagt
      121 tgctttaatt ttagctataa taggtgcgct taactggggt gcaattggta ttctaggcac
      181 agacttaata ggtagtatct ttggtggaac atatgaaatg ataagtagaa taatatactt
      241 cattgtaggt ttagctggat tatacttaat accaagttta atgtctgatg atagagaata
      301 atttatgctt ttatgttaaa tacctcattc taaatattta gaatgaggta tttaatttta
      361 taaaaatatt aatttgtttc ttttttaatg gtaaaataga taagaattga agttttaaaa
      421 agaagtatta tctaaaaaag gagtactatt aatatatgtt tattattaat gaattaaata
      481 agattgtaaa tgaagaagta atatcttttc atatgcctgg tcataaaaga ggagaggttt
      541 ataaaaagtt gggatataaa gatatactag agaatttgta taaaatggat acaacagaga
      601 tattaggaac agataattta cattttccag aagggattat aaaaaattca caagaaaaag
      661 catcaaaggt atttaaaagt gattatactt actatctagt aaatggtagt agctgtggaa
      721 tacaatctgc aataatgtca gtatgcagtc caaaaagtaa aataatagca aatagagatt
      781 gtcaccagtc tgttataaat ggatgtattt tgggagatat agatatagag tatgtacctt
      841 gtgagataag tgaagataca aatgttttaa aaggtatatc tataagtaat gtgattgata
      901 taatagataa aaacttggat gcaaaagcgg tactgcttac ttatcctaca tattatggga
      961 tgacatatga tttagaatac atatgtaatt atgcacatag caaaaatatg gtagtgatag
     1021 tagatgaagc acatggtgca catttagggc ttagtgaaag acttcctaaa acggctcttg
     1081 agcaaggtgc agatatagtt gtacagagta cacataaaac tcttccatca tttacacaat
     1141 cgtcaatgat acatatacag ggaaaccgag ttaatataga taaaatatta aacatgttaa
     1201 gaatgacaga atcttcaagc ccttcatact tattattatc ttctctggaa ttagcagtag
     1261 atatatatga aaataaagga aaaggattaa tggaagaact tttaaataat attagaactt
     1321 tcaaaaataa tattgattca aatattaaga tgtatgacac aaatgataaa acaaaaatat
     1381 ttatatcatc taaaaatatg ggtttaacag gttatgaatt agaaaatatt ttaagaaaca
     1441 aatataacat acaagtggaa ttatctaatt attatggagt tcttttaata tgcacaatag
     1501 gaaatactac taaagatttc tctagtttag aaacagcatt aaacaatgtt gtaaaggaag
     1561 aatttaaatt tacaaagcta gaaaataaaa aataccctgt tgttattccg aagaaaatat
     1621 taacacctag agaagcattt tataaaacta aaaaaagtgt taaaatatat gacagcatag
     1681 gtaaaatttg tggtgaatgt atagtgccat acccacctgg aataagtgta atatctcctg
     1741 gtgaagtaat aagtaaagaa ataatagact acctaatgtt ttgccattct aaaggtatga
     1801 ttgtgagtgg tttgaaagat gtatatttaa attttataca agtaatagat ttagaataca
     1861 tttaaaactt atgatataaa agtagatagt ttaaaatttc gaagagaaat aaatagactg
     1921 tttatataga gctatataat aagagtatta aaaaagtaaa aagtatttgt atggaggata
     1981 tgaaaatgaa aggtaagcta ataattatag agagtggttc agatgcaagt ggaaaggcta
     2041 ctcagacaaa aatattatat gaaagattaa aaaaagaagg ctatatgatt aaaaaggtag
     2101 aatatccaaa ttatgaatct ccatcatctg cattggtgaa aatgtattta aaaggagact
     2161 ttggtaaaaa tgcatcagat gtagacccat atatagcatc aacttttttt acagctgata
     2221 ggtatgcatc atttaaaacc gattgggagg agttttacaa tgaaggtgga atagttatcg
     2281 cagatagata tacaacctct aatatggtac atcaggcctc taaaatggat gtttgtgata
     2341 gagaaaagta tttaaattgg ttggctgatt atgaatttaa tttatttaag ataccacaac
     2401 ctgattgtgt tgtattttta gacgtgccta ttgaatttag taaaaagctt atggagaata
     2461 gaaaaaataa aattacaggg gaagaaaaaa aggatattca tgaaagtgac atagagtatt
     2521 tacagaaatc ttacaacaat gctttatata tagcagataa atatgattgg aaaaaaataa
     2581 attgtgtttt agataacaaa ttaagaagta ttgaaagtat acataatgaa atttataaaa
     2641 tagttcttga ttcaataaaa tctatggaga gataaatatg tattttgaaa atattatagg
     2701 gcaagatttt gcaaagaaat atttaacaaa ttctataaag aaaaataaac ttaataatgc
     2761 gtatatgttt gagggaatgg atggaatagg aaaaaagaaa tttgctgatg agttatcaaa
     2821 actattactt gattatgaaa atctcgaaaa tagtccagac tatgtactca taaagccaga
     2881 tggaaatagc ataaaaatag ctcaaatcag aaatttacaa tcagatatag taataagacc
     2941 tcatagagac tataaaatat atataattaa taatgctgaa aaaatgactc tggaagctca
     3001 aaatgcactt ttaaagacgc tggaggaacc tccaaactat gctataataa tcttagtcac
     3061 aaacaacaag gaatctttat tagaaactat aaaatctaga tgtgatataa taaagttctc
     3121 acctatacca attgaggact taaaaagtta tttgatagat acaggtatag aagaagaaag
     3181 agctcaatta ttggctactt tttcgagagg aagtattgag aatgctctaa atctatctca
     3241 gtcttctgag ttttcagtta tgagagaaga tgtacaacag tatattcaga taatgttaga
     3301 taaaaacata atagagattc taaatatacc aaataatatg gaaaaatata gaggtaagat
     3361 tatcacttta ttagatatga tgataaacta ttttcgagat attattctat taaaagaaaa
     3421 tgtaaacaag aacatgttaa taaatgtaga taagctggtc ttcattcaaa atatgagtgg
     3481 aaaaattagt tattctcaat tgtctaagat tattgatata atagaagatg taaagaataa
     3541 aataaaaagc aattgcaatt tcaatataag catacaagtt atgtctttaa atatatacga
     3601 ggtgattaaa tgataaagat agtaggtata aggtttaaaa gtgctgggaa aatatattat
     3661 tttgaccctg ttgattttaa tatagagcaa gatatggatg tagttgtaga aactgcaaga
     3721 ggcttggagt atgggaaagt agtcgttggt ccaaaagata tggatgaaag cgaattagtt
     3781 tctcctttga agccaattat aagaatagct acagaagaag ataaaaaagt atttctagaa
     3841 aataaggaaa aggcaaaaga aacttttgag ttatgtcaac aaaaaataaa agaacatgag
     3901 ttaacaatgt ttttaataga ttgtgagtat acatttgata gaaataagtt gattttttac
     3961 tttacagcag aaggaagaat agattttaga gaattggtaa aagatttagc tgctatattt
     4021 aaaactagaa tagaacttag acaaataggt gtcagagatg aagctaaatc tataggaggt
     4081 ctaggtcctt gtggtagaaa actttgttgt tcatcttggt taggtgattt tcaaccagtt
     4141 tcaataaaaa tggcaaaaga ccaaagttta tctctaaatc caacaaaaat atctggaata
     4201 tgtgggagat tattctgttg cttaaagtat gagcatgatg tatatagtga ggcaatagaa
     4261 aaaatgcctg ttgtaggtgc attggtgcaa tcagatgatg ggaaaggaaa agttgtagaa
     4321 gtaaatcctt tattagaaca aattaaagta gaatttcaag ataagacagt gaagatatat
     4381 acaagagaag atataaaaat acttagagag cctaaaaaat gtgatggctg tggtggtaaa
     4441 tgtaaggata atgatggatt agatgaggcc acactaagag agctaaagaa attagaagat
     4501 taaattcaag gtagggcttt tcctaccttt tttaaagcaa ttaatgctta aagttattaa
     4561 tatttgagga gaatttatat atgcaattaa aagattcaga aagaatagat gatttacaat
     4621 taaaaggcct taaaattata caagatacta atggtttttg ttttggtata gatgcagttt
     4681 tattagccaa ttttactaaa ataaaaaaag acgctaaagt agtagatttg ggtactggaa
     4741 ctggcataat acctattttg atagctggaa aaagtgaagc taaaaaaatt attggtgtgg
     4801 aaatacaaga agatgtatat gaaatggcaa ctcgttctgt aaaattaaat ggattagaag
     4861 aaagagttga gattataaat gaagatataa aatacataga caaagtctta gacgtaaatg
     4921 gttaccatgt agtcacatca aatcctccat atatgcatat tgatggaata aaaaatccaa
     4981 atgataaaaa agcaatatca agacatgaag taaggtgtaa tttggaagat gtaattagag
     5041 ctgcatctag attggttatg tctagaggaa aatttctcat gatacataga ccaacaagat
     5101 tggttgatat aataacttta gggagaaaat atagattaga gccaaaggtt attcaatttg
     5161 tgcatccaag acctcaaaaa gcacctaatt tagtcttggt tcaatttgta aaagatggaa
     5221 gaccagagct taaaatattg gacccattgt atgtttatgg agaagatggg aattatacaa
     5281 aagaattaaa agcaatatat aataatgaag atataggaga gttgtagatg agtggaaaat
     5341 tgtacatatg tccaacacca ataggaaact tagaagatat aacatataga actttaagaa
     5401 tattaaaaga ggtagacttg attgcggctg aagatacaag acatagtata aaacttttaa
     5461 atcattttga aatctcaaag ccattaacta gttatcatga acataataag gattcaaagg
     5521 gagaatattt gataaataaa ctaattgatg gtgaaaatat agctctgata agtgatgcag
     5581 gtatgccagg tatatctgac ccaggagaag agataataaa acaagctata caaaataaca
     5641 tagagataga agtattacca ggtgcaacag catttgtaac agctttagtt ggttctggta
     5701 tggacacaca taaatttgtt tttgagggct ttttagatag agataaaaaa gttaggaaag
     5761 cacaattgga agaattaaag gaagaaagta gaactataat tttttatgaa tcaccgcata
     5821 gattgaagga tacactaaaa gatatgttta aaattcttgg taataggaat atttctataa
     5881 atagagagct tacaaaaaaa tatcaagaga taataagaga aaatatagaa actacaataa
     5941 agatatttga agaaaaagaa gtaagaggag agtttgtatt aatagtagag ggttttcatg
     6001 gtgaaaagtc aaagaaagaa aattatgatg agcttactga tagggaatat gttttaaaac
     6061 taattgaaag tggtatgaac aaaaaagatg caataaaaat agtttgtaaa gatagaaagt
     6121 taaagaaaga tgtggtttat aaacaagttc tagatttata aaacctgaat ctgaggtgat
     6181 tttatggaaa taggaaaaat tataatagag agtttaaaga gagaagatac acataaaaca
     6241 tttatagaat tagatgataa gcatgaatta gaaaaaataa ttcctaaagt aagctgtatg
     6301 aaatctgtag gtgaatgtaa atatcatgta gtaaattgtt ttgaacactc tataaatgca
     6361 ttaaaagaat tagaaatagt attaaataat aaggattttt ttccaataca tctaagaaaa
     6421 catgtttcaa actatttaaa cacatatatt gaggaaggaa taaataattt acatgtatta
     6481 aagttaggaa catttttaca tgatataggt aaacctgata gcatgacttt agatgaaaca
     6541 ggaagagttc atttcacaaa tcatgaaaaa ataggtgctc aaataattga caatatgggg
     6601 ataaatctga agttatcaac agaaacatat agacttataa gtaaatatgt aaggtatcat
     6661 atgatacttt tgtctttgta taagaaaaat gatttaagta ggaaagaatt aattaatgta
     6721 tttaacttag tagatgagga cactatagga gtaataatgc ttggatatgc agatatagta
     6781 tctacagtaa aattattagg taagagtgaa gaagtcagtg tattaaagac atatatggaa
     6841 tatattttaa caaattactt gtataaaagt aattatacac atgtataaat ttagtcaata
     6901 taattgagtt ttaaatggtt aattgaagtt tgaaatatat agatttcaaa aacataaaag
     6961 aagttgtctt tgttgtaaaa ttatgaaaga caactttttt tatatcaaaa attgaaattt
     7021 tattaaggat acttaatggt ctattaatta ataaaccatt agtatttaat ttatattaca
     7081 atattgattt tgcttgtatt ggcgttgata gtataacaga ggtcttagta gaaccaattt
     7141 tctttatagt atcaatcaca ttttctagct cgtacatatc ttttacaatt acttttaaaa
     7201 gtaagcaatc atcacctgtt atatggtgac attctacaat tctagggtcc tttgcagctg
     7261 actcaataaa ttctgtatat ccattacttg gaagagatat atgaataaat gcctttataa
     7321 ctctacctaa tgaatctggg ttgacaatag ctttatatcc ttctataaca ccagactctt
     7381 ctaatctttt gactctttct gaaactgcag gagaagttaa accaactatt tttcctaagt
     7441 ccttcataga aattctccca tcatcctgta aaatttctat gattctgtaa tctgtaacat
     7501 ccataaataa acagtccccc ttaaataaaa ataattaatg ctataaaact tttttagaat
     7561 ctatcatttg tgtttttaaa taccaaagat ttctagataa atcaacctta taaatgtgtg
     7621 gttttgaaag tcttttgtat tgttcccaga tagtacttaa ttcatattgt acatgatttt
     7681 ttatttcaag aacagctttt ttattatatt tgcatatgcc ttttatatac aatggtttaa
     7741 gaagctcttt aactttgtaa tttgtaaata cctttgtttt ccatgtataa gtaggatgga
     7801 agatttctaa aggtttagac tcatctataa cttcatcatg taacataatc aaatctgcct
     7861 ctgccttatt gtcttcgtta tatattctta taactttctt gtacccagga ttatttattt
     7921 tttctggatt ctcagaaatc tttattttag gttcaagaac tcctttttca caagatgcag
     7981 ctaatttata aactcctcca agagaaggtg aatcgaaaga tgtaatgagc tttgtaccta
     8041 ctccccatga gtttatagta gctccctctg ctttaagtga tgttatggta tattcgtcta
     8101 ggtcattaga tgcagtgatg ctaatatctg aaaagccagc attatctaac tgttttttag
     8161 cttctttaga taaataagct aaatctccag agtcaagtct tatacccata ggtttgtatc
     8221 ctttttcaga aatatttttg aatactttta ttgcattagg aactccacta tttaacacat
     8281 cataggtatc tacaagtagt aagcatttgt ctggataaac atcagcatat gcttggaatg
     8341 cttcaagttc attatcaaat ttttgtaccc aactatgagc ttgtgtacca attataggta
     8401 tatcaaacat tttccctgct agtacatttg cagttccagc acaaccacca actacagcag
     8461 ccctagctcc atatatacct gcatctggac cttgtgcacg gcgtaatcca aattcaaata
     8521 cagggtctcc ttgagctgca aagcaaactc tagatgcttt agtggcaata agggactgaa
     8581 aattaactat tgtcaacaat gctgtttcaa tgagttgagc ttgatacaaa ggtgccttaa
     8641 cagtaattaa tggctcatta gggaacatga tagttccttc ttcaacagca tatatatctc
     8701 ctgtgaattt aaattctttt aaaaatttta agaacttgtc agaaaataaa tttaagtttt
     8761 ttaagtactt taaatcttca tctgagaaat gaagattatc tatgtattca acaacctgat
     8821 caataccaca aactatagta taccctccat cacaagcgtt ttttctaaaa aacatatcaa
     8881 atacaacaat gtcttcatga atattctttt caaaatagcc atttaacata gtaagctgat
     8941 ataaatcagt aagaagtgtt agatttctca ttatttctct ccttaattat tattaaatat
     9001 taaaaattgt aaaaactccc acacttatac taaaacataa tatagtacaa ctttcaagta
     9061 taaagtatta cctaactatc ataaaattat ttaaagagga ggatgattat aataggaaaa
     9121 atatggtttt atatggtatc gatagggata ataggaagtt taatttctaa aaatatgggt
     9181 gaattaaata aagttatatt aagtgaaaca tcaaaaggta tagagtttgc aataagccta
     9241 gctggtatca tggcactctg gatggggata atgaatatag caaaagagtc aggcttaatt
     9301 gaaaagatag gtcaaaaatt aaatcctata atgagaagat tatttccttc tatcccaaaa
     9361 ggtcataagg caatgtctta tatagttatg aatattgcct taaatatgtt gggtgctgga
     9421 aatggtgcaa cagcatttgg tttaaaagca atgagtgagc ttcaaacttt gaataacaag
     9481 aaagatacag ctactaatga tatgattatg ttcatggtaa tcaatatatc ctctatacaa
     9541 ataattccat ttactataat taaattaagg atggatatgg gagctcaaaa cccaagtgaa
     9601 ataattttta cgactttatt tgcaaccata atatctacag taatagcgat aataacatgt
     9661 aaattttttc aaagaagata tagataaagg ggatgtagat acatggagat attttcaaac
     9721 ttacttatac caataataat tttgtacata gtagtttatg gtaaatataa aaaaatagat
     9781 gtgtatgata gttttgtaaa aggagcgatt gatggattaa aagcagcatg ggatatccta
     9841 ccatatataa taggtatatt tctagcaata ggaatattca aaactggtaa aggtcttgat
     9901 atgttagaat ggctatttac tccaattgca aatatgatga gtataccaaa ggaattaata
     9961 ggtctaataa gtgtaaaacc tttatctgga agtggtgctt tagggatgta tagtgaactt
    10021 gcaaatagag ttggaatagg aagtttggta gaaaaaatgg gtgccacgat tgtaggttct
    10081 tctgagacta ttttttacac aatggcaata tactatggaa gtctgaagat aaaaaatact
    10141 agacatacat tatcatgtgc tatgattagc catgttgcag gtgttatagc agctgttttt
    10201 atttgctatg taatatttgt ataatttgtt gacaatatgg gaaaaatttt ataatataat
    10261 gattatatag aaacaaatag taatataaat tacaagctat gaaaagaaga gtaaataaag
    10321 gttttttcta tcagagagct agattaggtg aaagctagtg tcaaaagctt tattgaagat
    10381 ggtcttggag ctttttatct gagcaagtgt gctagggtaa aacggttgga cacgttatag
    10441 tctactaagg tatctataaa atgatttcta catttcatgt gaaacataaa cattatagat
    10501 gaattagggt ggtaccgtga ataatctcgc ccctatgtta actcatagga ggcgattttt
    10561 tattatttaa atgaaagaat catatgatta cgaacgataa aaaattagga ggtaaataat
    10621 atgagtaaac cgagttttta tgtaacaaca ccaatatact atccaagtgg aggattacac
    10681 ataggacata cttattcaac agtagctgca gatacaatag ctagattcaa gcgtttctgt
    10741 ggatatgatg taaaattctt aacgggaaca gatgagcatg gtgaaaaaat tcaaaagaaa
    10801 gccatagagc aaggaatgtc agagatagag tatcttgatg gaatgataaa agatataaag
    10861 gctttatgga atactatgga tatatcttat gatgatttta taagaactac agaaaaaaga
    10921 catacagata taatacaaaa gatatttact aaactatatg agcaaggtga tatatataaa
    10981 ggtgaatatg aaggtagata ctgtactcct tgtgagagtt tctggacaga atctcaatta
    11041 ctagaaggaa ataaatgccc tgactgtgga agagaaacat atttagtaaa agaagaatct
    11101 tatttcttta gattatctaa atatgaagat agattaaaag agttatttaa agatgatagc
    11161 ttctgttttc ctgctgctag aaaaaatgaa atggtagcaa actttttaga caaaggatta
    11221 gaagatttaa gcgtaactag aacgactttt gactggggta taaaagttcc ttttgatgaa
    11281 aaacatgtaa tttatgtgtg ggtagatgcc ttatgtaact atataacagc attaggttat
    11341 atgactgata atgatgaaga atttaaaaaa tattggcctg ccaatgttca gatagtaggt
    11401 aaagaaatag tgagattcca tacaataata tggccagcac ttttaatggc tttaggtcta
    11461 gaagttccaa aacaagtatt tgggcatgga tggatactgt ttgctgatga taaaatgagt
    11521 aaatcaaaag gtaatgtggt ttatccagaa cctataatag aaagatatgg aatagacacg
    11581 cttaagtact ttttattaag agagtttgca tttgggcaag atggaagtta tactcataga
    11641 aattttgtaa caagaataaa ttatgattta gcaaatgatt taggaaactt aataagtaga
    11701 actgtagcta tggttgaaaa gtacaataat ggtataatac caacagcaaa agtttcaact
    11761 gattttgatg ctgatttaaa agagcaagct gtatcaacta gagaaaactt tgaagctgaa
    11821 atggataaga tgcaattcca tgaagcatta gagagtgtat ggaaactagt tagaagaact
    11881 aacaaatata tagatgaaac tatgccttgg gcactagcta aagatgaagc taagaaagat
    11941 gagttagaca cagttttata taatttatgt gaatctataa gaataatcgc aacactaata
    12001 aatcctataa tgaatgagac tgctaataaa atatatgaac atataggaat aaagggtcaa
    12061 gatgatataa ctacatggga aagtacaaaa acatttggtc ttattggaga aaatgtaaaa
    12121 gtatttaaag gtgaaccttt attcccaaga ttagatgtag aaaaagaaat agaagagtta
    12181 actaaaatgt tctctggaaa acctccagta gaagaaaaac ctttagagca taaagaagaa
    12241 attactattg atgatttaga caaaatagag cttagagtag gaaaaatatt aagctgtgaa
    12301 aaacatccaa aagcaaataa attattagta tcgcaagtta agattggacc agaaacaaga
    12361 caaatagtat caggaatagc tgaatactat aagccagaag atttagtagg aaaagaggtt
    12421 acagtagtat gtaacttaaa accagttaaa ttaagaggtg tagaatctca aggtatgata
    12481 ttagcagcag gtgatgatgg agacccatat gttttaccat ttacacaagg tgctaaagat
    12541 ggatgcgagg ttcgttagta ggcaattaaa gagtaaggag attaaagatg ttatttgact
    12601 cacatgcaca tttaaatgat gaaagttttg atgaagatag agatgaactt attggttcat
    12661 taaaagataa aggtgtagat ttggttgtaa atccaggagc agatatagat acgtcgataa
    12721 cagcaattga acttgcgaaa aaatacgact ttatatattc agcagttgga gtacatccac
    12781 atgaggtatc aaaactagat gatacagcaa tagaaattct aagaaaactt gcaactgaga
    12841 atgaaaaagt tgtagctatt ggagagattg gattagatta ttattatgat tattctccaa
    12901 gagaagaaca aaaagagtgg tttaagaagc aaattgaatt agctaatgag ctaaagcttc
    12961 caataataat acatgataga gatgcacatg gagatacttt tgagataata aagaatacta
    13021 agagtcctga aataggatgt gtacttcatt gttatagtgg aaatgtagag ttagctagag
    13081 aatatgttaa gatgggttgt tatatatcaa ttccaggcac ggttacattt aagaataata
    13141 aaaaaactag agaagtagta agagaaatac ctctagaaag attattcata gagactgatt
    13201 caccatatat gtcaccggag ccacatagag gaaagagaaa taatccttct caagtatctt
    13261 ttgttgctga taagatagct caggaaaaag gtatatctta tgaagaagta tgtagagtta
    13321 caaaagaaaa tgcaaagaaa ttttttaata taaaatagac aaattaagtc ctataatggt
    13381 atataaaata agtcattata agtatagaat gagggtgcct caaaatgaat tttttagttc
    13441 atgaggtact cttttttata tgaaatcaaa tatattttcg tcatttcaac aatgaaaaat
    13501 aagtttatcc tattttgata cagtctattt ctatttattt aattcatatt ttaaaatata
    13561 tttttttaac attgttaaaa aagaatttac aagatattca ctagaattaa ctcaactata
    13621 atattcattt aacttacctt gtttattata ttattaaaga gaagtaaacg aaggacagat
    13681 taaggaggct aaattttgta tacagttgat agtactaaga tattgataaa tatgaactta
    13741 gagaaactag aaaagatata ctcaatgtta aagtatacat caaatgtttc tataattaaa
    13801 gaacctaagt tggctacagt aatggaagag ttaatgaaaa tgtaaaaaat acaacattta
    13861 atttagggga tatattagtt actgaatgta gtgtagaggt agatgaaagt ttgggttacg
    13921 gaatagttgc agaaaaaact aataatttaa ataaagcagt aagtttattt acctcaagca
    13981 ctattaaagt tggtatatat gatgaaagaa gtagtgtaaa agaaaataaa aagcagattt
    14041 agtttcagta gatattaaca gtgaatatcc aaagcttgta agtattattg taaatggaaa
    14101 agcagtttat aaaagggagg tataaagatt gttaacagag ttacactgtc atacaaatat
    14161 atcagataat aattttacta ctgaagaaat aataaaaaaa gcagcagaaa agaatataaa
    14221 tatcttagca ataacaaatc atgacacatt atctggattg gatgaagcca ttgtgcttgg
    14281 agaacattat ggaataacaa taataccagg tatagaaatt tcagcttatg attatataaa
    14341 tagaaaaaga gttcatattc ttggatataa catagattta aacagtcaag aaataaaaaa
    14401 tttgtgcaat ccaatggtat gtgacagaca caaagcatct gttaagatgg taaataaaat
    14461 tatagattta gggtacaaaa tatctctgga ggatgtaaag aaatattcat caaagactgg
    14521 aatatttaaa caacatataa tgaaggctct tatagataaa ggatatacag ataatatata
    14581 ttcaagtcta tataaagaac tgtttcatag aggaaacggt aaggtatatg tatctttaag
    14641 atatgtagat tatagagatg caataaaagc tataaaaaat tctggtggaa tttgtgtgtt
    14701 agctcatccg ggtcaaatgg ataattttag cgctattgaa gagatggtaa aagtaggatt
    14761 agatggaata gaagtatatc atccatctca taacaaagaa ctagaaaaag aatcgctttc
    14821 ttatgctaag aagtacaatc tagtggtcac aggaggctca gattaccacg gattttattc
    14881 tcaacataat tatgaacttg gaagtaagag cttaaataaa gaagatttat ttaagtttag
    14941 gttagcttta ggaggggtat tataaatgtc ttttttacaa gtaaaaaatg tatgtaaaag
    15001 ttatggacaa gttaaggtgt taaaagatat atctattgat attgaaaaag gagagtttat
    15061 ttgtttacta ggaccaagtg gttgtggcaa aagcacactg cttagaataa ttgcggggct
    15121 tgaggataaa catggtggga aaataataat aaatgataga gatatgacta attcaccacc
    15181 tgaaagtaga aattttggta tagtttttca atcatatgca ttatttccaa atatgaatgt
    15241 ttacaaaaat atagcttttg gactagaaaa taaaaacata agtaaatcta acattgataa
    15301 aaaagttaaa aaagttctag aagttgtaga attaagtgga tatgagaaaa aatatccatc
    15361 acaattatca ggtggacaac aacaaagggt tgcattagct cgtgcgattg ctttagagcc
    15421 agacttttta cttcttgatg aacctttatc tgcattagat gcaaaagtaa gacttaaact
    15481 tagggagcag attagaagtt tgcatagaaa actaggcatt acaactataa tggtaacgca
    15541 tgaccaagaa gaagctcttt gtttagctga taagatggtt gttatgaata gaggagaaat
    15601 aatacaagtt ggaactccaa aggaagtata taaaaatcca gaaacacctt ttgtagctga
    15661 ttttatagga acaataaatt ttatagataa tggtattaat aagatagcta ttagaccaga
    15721 agacataaag gtagagttca atagagattc taaagataaa gatataaaag agggagagat
    15781 tttggatata gaatttagag gatttaacta tagaattaca gttgagtatt gctctaagca
    15841 aatgaagtta gatgtagttt caaaagttgc agaacaaatg aaactgtgta taggttctaa
    15901 aataaacttt aagataccta aagaaggaat tgtacaatat aaatcagagg gatgtgctta
    15961 atagctaggg atgaataaat gataacatca aaaaataaaa gaagaataag tgatagcaca
    16021 atacaaaaat atttcttgat tttttcagta attgtactaa tagtatttat attatttccg
    16081 ttagcatcat tattaaaaaa tgcatttatg gatacaagtg gaaattttat aggaatttta
    16141 aactttagta aatatattga gaatccaagt cttatcgcat catttaaaaa ttcaattttt
    16201 gtatctatag tctcatcttt aatatcatta tgtttagcat ttatatattc atacgcaata
    16261 acaagaacaa atataaagtt taaaaacttt tttaaaacta tgggaatgtt tccacttttt
    16321 gcaccaacta tgttatatgg tatttcactt atataccttt ttggaaataa gggaatcttt
    16381 acaaccatgg gtctggaagt accactatat ggtccattag gaataattat ttctcagatt
    16441 ctatttacat ttccacaagc ttttttaata ttatctgtag cactttcgat ggctgattac
    16501 agactttatg aagcagcaga tagcttgggt gctagtgaat ttaagaaatt ttgcaaaata
    16561 acaattcctg gtataaagta ctcattactt agttcattct ttgtatcctt tatacttgca
    16621 tttacagatt ttggagcagc taaggtagtt ggaggaaact acaatgtact ggctactgac
    16681 atatataaac aagtagttgg acaatttaac ataccaatgg gagctactgt ttctatggta
    16741 atgttaattc ctgtactaat agcatttaca ttagataaga tggcaagtaa gaaacaaggt
    16801 atgaccataa ctgcgaagtc tatgccatat aagattaaag aaaacaagtc tagagataga
    16861 gcgtttttaa tagtatgtag tcttataacg ttgctaattt ttattttgat atttgtttca
    16921 gttataggtt cagttataaa attatggcca tataatttaa gctttacaat ggaacactat
    16981 acatttaaag gtattttggg aagtggaata aaaacatatt taagcagttt gaaaatatca
    17041 actttaacag cagtatttgg aactatattt gtatttttta gtgcatatat gatagaaaag
    17101 gtggataagt ttcctaagtt aagacaaata gcttactttt tatcaatgat accaatggcc
    17161 ttgcctggct tagttttagg tatatcatat ataacttttt ttaactcagc aagtaatcca
    17221 ctaaattttt tatatggaag tacagcaata ctagttatag taaatatagt tcatttttat
    17281 tcagtttgtt ttataacttc aaactcatct ttaaaaatgt tggatataga ggtataaagt
    17341 taaaagagga aggctatcca gtagaagtag tatttccaaa agaaggttct ggatgagata
    17401 tagaagcaaa tgctcttgtg aaaaaagata atataaaaga agcctcaaaa gtatttttag
    17461 attgggcaat aagtaaagat gcaatgaatg aatattctaa gaactatgca gttactacta
    17521 tttctacggg aaatccaata ccagaaggat ttcctaaaaa gccattagag caaatgatag
    17581 ataatgattt aaaatcagca gcgaaaaata gagaagatat actaaataaa tggatatcaa
    17641 aatatgatgg taagacagaa aaagagagtt aagcctgaca ataaaattta atacaaaaag
    17701 cgcctagaat ataaatttta tatctaggct cttttgatgt gtttgtttaa aatgcatatt
    17761 tctatataaa aataaatagt ttagtacctt gattaaatta aataaaaacc ttaaaataaa
    17821 gagatgtaaa gaaaaattaa aaacgaataa aaggtgaatt tatatgataa aagaaataat
    17881 agtagtagag ggtagagatg acgttacagc agttaagaga gcaatagatg cagaacttat
    17941 aactacaggt ggatttggat ttccaaaagg tgtaatggag cgtataaaag ctgctaatga
    18001 aagacgtggt gttataatat ttacagaccc agattttgca ggtgaaaaaa taagaaaaaa
    18061 aatagcatca gaagttccag gttgtaaaca tgcatttctg ccaagagagg aagctaaaaa
    18121 ggatggagat ataggtattg aaaatgctac tcctcaaagt ataatagcag ctttgaataa
    18181 ggttagaact gaaaatacag aaaaaagaga tgaatttaag caaattgact taattagaaa
    18241 tggtcttata ggtaatgaag aagcatcact tagaagagat gcacttggaa aaatacttgg
    18301 aatcggatat ggaaatgcaa aacaattttt aaatagattg aataattatg gagttgaaag
    18361 agaagcattt atagatgcat taaaacaaat ataaatgtaa tgtttaatat atgaaaaata
    18421 tgtatataaa ataaattgtg gaattacggt taatttaaga taaattattt ataatatata
    18481 ccttatttta aatcaatgta aatacatata aataagtata attaataaaa ttaaatatca
    18541 aaataagtta aaaaggagta aataatggat agactatctt cacataatgc aacaaaggaa
    18601 gtagtacaaa aatataattt taagttttca aagtctttag gtcaaaattt cttgatagat
    18661 agtaatataa ttgataaaat cttatctgga gctagaatca caggaggaga taatatcata
    18721 gaagtaggac ctggtatagg aactcttact cgtgagatgg gtaaaatagc agaaaaagta
    18781 gtggctatag aaatcgatag aaatctaatc cctatattga aagataccct gtcagattta
    18841 gagaatacag aggttgtaaa tcaagatata ctaaaagtag acatacagga attagtaaaa
    18901 gataaattaa atggtggacc agttaaactt gtagcaaatc ttccatatta tataactact
    18961 ccaatagtta tgaagttttt agaggaagat atacctgtaa cagacatagt agtcatggtt
    19021 caaaaagaag ttgcagatag aatgaatgct attccaggta ctaaagatta tggtgcatta
    19081 tctatagctg ttcaatacta ttgtgataca gagattgtgg caaaagcccc aagacatatg
    19141 tttataccac aaccaaatgt agattccacg gttataggct tacatgtaag agataaaaga
    19201 aaatatgatg ttcataatga agaaatattt tttaaaacag taaaagcatc ttttggacaa
    19261 agaagaaaaa ctcttcttaa ttcgttggga ggtcttggct ttcttaataa agatgaaata
    19321 agagaaatat taaaagaagc taatatagac gaaaaaagaa ggggtgaaac gcttagtata
    19381 gaagagtttt cagttctttc aaatataata aatacaaaag tatcttctaa atagaaggta
    19441 ctttttttta ttttgttaac atatattgtt tagagaaact gtgttaaggg gggattgcag
    19501 tgggttctaa aagaaagttt aaaagagact atataatact agaagctaaa gacataaact
    19561 ttagatacaa agaacgagta ctgccaaaag cttttgcaaa agttgaagta aacgatgaaa
    19621 aagcaattat tgcattatat gtagaaaatc taaaatatgt taaagatggg tataaagcag
    19681 tagcaataaa agatgaccat ggattaatag acttaggaaa tataatttta aatgaacaag
    19741 gaagaggtga atttgtttta gatttagaag attatgatga tgagataaaa ggtattgcat
    19801 tattgtatga aagaaatata cctttaattg gatttaaggg aaataagctt gaaaattatg
    19861 aggatatatt attccaagag gtagaggaag aagaatatga agaattggaa gaagaagacg
    19921 aagaggtaga ggataatgag gaaagtaata gagacgaaga tattgaagaa gaagaatata
    19981 ttatagaaga atatgatgaa gatgagtatg aagactattg ggaagatgat gaagatattg
    20041 aagaaggaga attaaaagca agaacggaag tagaagattc tagtaatgaa gaaatagaag
    20101 agttcaataa ttacaaggaa atagaaaatt ataatagggt taaattacag gaagaatata
    20161 tagacataga atgtgaagag gatgaagaag aggatgaaga agaagttttt gaagtaaata
    20221 gagaagatga caggtttgtt tcttcaaaac ctactaaatc aaagaaagtt caaaaagagc
    20281 agaataatat tgaaaaaata aaaagagtca atggagtaag tcaaggagag agtggaaata
    20341 aacaaaccag tacattactt atgccaagac aaataaaaaa aggtttgaaa ttatttaaag
    20401 aagtaaaacc ttttgtaaca gattatatag ataagacaag atggtggaaa atagagataa
    20461 atcctacaac attatgtgga tatacaatgc cttatttagg atatttaaac gtgttgaatt
    20521 atactatgta tagtgatgca gttttacatt catataaata tagacactat ttatttggag
    20581 ttcagtatga tgaatataat aagagaaaac attatattta tgctatccca ggaaatagaa
    20641 atgaacagcc agacaatgga agcacaggat ttttaagata tcaggcttgt gataatagaa
    20701 caaatagttt agggtattgg ctatgtttta tagattctag acaaagaaat atagttaggt
    20761 aaaaataata aaaataaaaa aatttagact caatttttat tttactgaaa aaattaatga
    20821 aatgcagtac aaaactttaa aaactattga taatatttaa atattacact acaatatatc
    20881 ttgaaatacc tattatatta tggaggaaaa ttatgataaa cgagcaaaga attttaaatg
    20941 agtttcttga attagtacag atagacagtt tatctttaaa agagggaaat gttgcgaaag
    21001 tattagttaa aaaattagaa gaaataggtt gttcagtagt agtagacaat gctggtgaaa
    21061 aagcaaatgg agaaactggt aatataatag ctacactaaa gggaaataaa gaaggaaaaa
    21121 aaatattatt tagttcacat atggatacag taactccagg tataggggta aaacccatag
    21181 tggatgaagt aaacggaata ataaaaagtg atggtactac aatattaggt tctgatgata
    21241 aagcaggtat agcagctata ttagaaggat taagatatat aaatgaaaat aacatagaac
    21301 atactgatat acaagttgta ttctctatat gtgaggaatg tggattagtt ggagctaaaa
    21361 atttagacta tggaaaaata gactctgaat atgcttttat attagatagt ggtggttctc
    21421 caggggaaat aatagtaaaa gctcctgcac aagatgtaat aaatgttaag atattaggaa
    21481 agactgctca tgcaggtctt gaacctgaag ctggtataag tgctataatg gtagctgcca
    21541 gagcaataga aaatatgaat ttacttagaa tagatgaaga aacaactgct aacataggaa
    21601 ttataaacgg tggaacagct acaaatatag taacaggaga agttaatata gttgcagaag
    21661 ctagaagttt aaaagaaaat aaattagatg ttcaaactaa acacatggta gagacttttg
    21721 aaaaagctgc aaaagatttt ggagctcaaa ttgagataga tgtcaataga gcatatacac
    21781 caatagatgt tagtgaagat tctgaaataa taaaacttgc aaagaaggct ttttcaaact
    21841 taggtataga aggtcacact gaatctacag gaggaggtag tgatacaaat atattaagta
    21901 agaatggtat cgaagctata actttaggaa tcggtatgaa aaatgctcat acactaagtg
    21961 aacatatagc tataaaagat ttatatgatt ctgctaaaat ggtagtggag ataataaagg
    22021 aagcataaat ttaaataata gtgtataata tatatatcgc ctagcttaag ctaggtgatt
    22081 tttcatttta tagaagattg ataatctcta ttgaaagcaa agagtataca tttgcatata
    22141 agagagtgtt taatttatat tcagatgtag gttcttaata atatttagat tgtttcataa
    22201 gggaggaata aatatggaaa caaggtatga agaagcaaat aaaataacaa tacaatcaat
    22261 actttggaat gtagtattaa caataattaa ggttatagct ggtgttattg gtaattctag
    22321 tgctatgatt gcagatggat tacattcagc atcagatatt ataagttcta taggagtatt
    22381 aataggcaac tatgtatctt ctagacctgg agatagagag cataattatg gtcatgagaa
    22441 agcagagaca ttagtgtcat ttgtgttatc aatactgctt attttcgttt ctataacaat
    22501 aggtatagag gcaattaaat ctttatttaa cttagatgca ttgagtgttc catcaatatt
    22561 gccattagta gtatcagtta tttcaatcct gataaaagag tatcaatata gaataacaat
    22621 aaaagttgct aaaaagataa attctccagc cttaaaagct gatgcttggc atcataggtc
    22681 agatgcttta tcttcagtag ctgcttttat aggtataggt ggttctattt tagggtttaa
    22741 gccattagac ccaattgcat cagttgtagt ggctatattt gtggctaaag taggaattag
    22801 tatacttata agttctgtta atgaattgat ggatgtttca gttgatgaag aggagataaa
    22861 agaattaaaa tttattgtag cagatacaga aggtgttaaa aatcttggag atataaagac
    22921 tagaaaacat ggagctatgg catatgtaga tttaactata tgtgtggatg aagatttgac
    22981 tgttaagcaa ggtcatgata ttgctactaa gcttgaaaaa catataataa aacatatgga
    23041 atttgtaaaa ggcataacag ttcacgttga accatgtact aattgccaag gaaataagtg
    23101 taataattaa ttaaaactta aaaaaaagtg taaaaagtta tataattgtt ttatgattat
    23161 aaactctagg ggtggttaaa tgagcaaaaa gagaaaacta aagaaaaaag ctgcaatatt
    23221 gataggagtg gttgttttct ttataatata ctttatatcc tttagaatag gaataaatat
    23281 ggaaaaggat aaaagtgaag tgccaaagaa ggtagaaaaa gaagaagaag ataataggtc
    23341 tttaaggact caaataaaag aaaagaagaa ggtttatata tcagataaaa atatagaaaa
    23401 cataaaaatt gaggaagata tgtgggatga aataaagtta tttttctcag attttaagaa
    23461 agtaagaaat actacttctt cttatgaagc agtctatgaa ggctattctg atgatggagt
    23521 taaattttct actgacctta acttttttag agtatatact gtaaacaaag aagaatatta
    23581 taaagtgcca gttagttcta aggatgcttt taagaaactt ttagatgaga gtatatatac
    23641 ttcgtttgac cttctaagtc attataaaga ttggaaagag gttactataa cttatggtaa
    23701 agaaattaaa aaagttcata gatggaagtt tgatgattta gcacataaga tgatttcaaa
    23761 aagggttgta ggaaaagttc aacctgaaaa aagtaaggaa agaagtgact ataattttac
    23821 tataaatata aaaggtgata attttgatgt aaaagttgat acaatgggaa aagattatgt
    23881 aaaagttact tctaagaaaa atgtatctta ctatgaggtt catacaagtt tatttgatta
    23941 ccttaaaaat gaaatatttg aaattggaaa gaaataatac tttaagaagg ctatcaaatt
    24001 agatatttga tagcctaaat tgttttattt attatttttc aaccaacaag tctgcaacct
    24061 tataaattgg accagcacca gcagttatta ctaaatcatt gtccttaaca ttttcacgta
    24121 agtattttac tatatcttca aattctttta tatatatggc atctacattg ttttgatata
    24181 atttctcaac caagtcctta gaatgtatat ctccggggtc tttttctcta gcagcatata
    24241 tatctgttat gataacttta tcagcagcat agaatgcttc tgaaaattca cctaaaagag
    24301 attttgttct agtataagta tgtggctgga agatacacca taaagtagat ttttttaatt
    24361 ttttggcagc agctaaagta gcttttaatt cagttggatg atgtgcataa tcatctacta
    24421 ctaaagcatt cttataatac cctttagttt caaatcttct tccaacgcct ttataaattt
    24481 ttatattttt tcttatagtc tctaaatcaa taccagaaac aagagctgcc attatagcag
    24541 aagaagcatt gtatatgtta tgaagaccat atacagaaag ttcaaattct cctaaatctc
    24601 ttccttgata ctctattcta aatattccat gaccactatt gtcaaagtga atatctttta
    24661 ttacagcatc attgtcagaa tctctaccgt attttataat agtagcttta acatcataca
    24721 atatgtcatc aatattttca tcatcaccat ttattatgaa atagccttct ggaggtaata
    24781 attttccaaa tttgttaaaa gaagctttga tttcatctat cccagagaaa taatcaagat
    24841 ggtcctcttc aacatttaaa actatagata ttttggggtt aaaattaagg aaactatcta
    24901 catattcgca tgcttcagtt ataaagtggt tggaattacc tatcttaaca ttaccaccta
    24961 tcatacttaa gttgccacca actagtatag ttgggtctaa gtctgcatat tcaaagattg
    25021 tagataacat agatgttgta gaagtttttc catgtgttcc agaaactgct atagaatttt
    25081 tatattccct catgatttgg cctaaaaaag tcgctctgtt cattactaat ttgttttttt
    25141 ctttagcagc cacaagttct tcattgtctg ggtggactgc tgctgtataa acaaccatat
    25201 ttacatcatc tgatatatta tcttttttct gaccaatata aatagttgcc ccttggtctc
    25261 taagtttgtc tagtaggtat gattcgtttg aatccgaacc tgaaacttga taacctttat
    25321 tgatacatat ttcagctaat gcactcatgc tgataccgcc aattcctata aagtgtatat
    25381 tcataataaa accacctttc tttttaatta agtcctacaa tatgaactat ttctgtggta
    25441 taataatata atgttcaata ttttataatt aatatgcata taatattata tgtattttat
    25501 ttttgaatat aataaaacat aagtaatatt ataccacaat aagaattgtt atgcattagt
    25561 tagtttaacg ttatataaag gtacttgtag gaggaaataa taatgaaatt taaaagaaca
    25621 gagagaattg gagcaatagt taaaatactg tctgataatc caaataaaat atatacatta
    25681 agttatttta caaatcaatt taatgcagca aaatcaacaa taagtgaaga tttattagtt
    25741 gtgaaaaatg tatttgagaa gttacactta ggtaaggtca taactatctc aggagcagca
    25801 ggaggagtaa aatatatacc taaaacttct atagcagaaa atgcagagtt tttaatggag
    25861 ttatgtgaga gaatatgtga caagtctaga atattatctg gtggattttt atacttgatt
    25921 gacataattt atgaccctac aatagctgct aagataggaa agatatttgc atcaaatatt
    25981 gagtatgtag atgcagatta tgttgtgaca atggaaacaa aaggtatacc tatggcactt
    26041 atgactgcaa aagctatgaa tttacctcta gttataataa gaaaagatat aaaggtatca
    26101 gagggtccta cacttagcat gacatatgtg agtggaaaca gctctaaagt tgaaagtatg
    26161 agtttgccaa gaaaagctct taaaccagat agtaaagtta taataataga tgatttcatg
    26221 agaggtggag gtactataaa aggaatggta gaccttatga atgaatttgg tgcagaagtt
    26281 ataggtactg gagtattcat atctacaacg aatccttcag aaaaaatggt aaaagattat
    26341 atttcattaa ttcaattgga tgttaatgga gataaaatag tagtagaacc aaacttaaag
    26401 acttttaaag atgaatatag aaatgaagat ttagatgaag aagaagattc agaatttgaa
    26461 tttgagatag atgaagatta ataaaaaaaa tatttagaaa aatatgtaaa aataaaaaga
    26521 ggatatccct agttgttcat agaattattt aaaaaacagt ttatattaat ttattccagc
    26581 gataataatt ttaatataaa ttaatttctg tcaaaatcaa agggggatat tttggtatga
    26641 agataactga cgtaagagta agaaaattaa cagaagaagg taagatgaaa tgtatagttt
    26701 caataacttt cgataatttg tttgtagtgc atgatataaa agttatagaa ggccataatg
    26761 ggctatttat agcaatgcct agcagaaaag taggcgaagg aaatttcaga gatatagctc
    26821 atccaataaa tgcagaaatg agacaagttt tagaagatgc agtattacaa gcatatcatg
    26881 aagcattagt tcaatgggaa gtagctgctg aataataata aatatataaa atggagagag
    26941 cccgaacatt taggctcttt ttaaatgtag aatttctatt aaaatatgta ctttttagta
    27001 aaaaagtgct atattattag tgataatgta tatgttgtat acaaattgtt agataaatgt
    27061 attataatgt atattgatta agagaataat acgaataaaa ttaaattaga ttgaatggag
    27121 tgtatcaatg aactttaaag ctataatcct tgctgctggc aaaggaacaa gaatgaagtc
    27181 taaataccca aaagttatac ataaagtatg tggaaaagaa atggttaacc atattataga
    27241 tgtttcaaaa aaatcagggg taaaagatac tgtcgtgatt ttagggcatg aagctgatgt
    27301 agttaaagaa aagcttgcag aagaaattat aatagccatg caaacagaac agcttggaac
    27361 aggacatgct gtgaagatgg ctaaagaata tattaatgat gaagatacaa tagttgtact
    27421 ttgtggagat actccactta taaaagaaga gactctgaag agactatttg aatatcatat
    27481 agaaaataaa tatcatgcta cagttcttac aacaagagtt ggaaatccaa caggttatgg
    27541 taggataata agagataaga agggtgatct tcttaaaata gtggaacaaa aagatgcaaa
    27601 ttcagaagaa aaaatgataa gtgagataaa ctcaggaata tattgtttta atggaaagag
    27661 tcttagagaa gcactagatt tgctaaataa taacaattca caaggtgaat attatttaac
    27721 tgatactgct aaaataatga gagataaagg attaaaagtt ggtgcatttg caggttcaac
    27781 tattgaagaa cttatgggcg ttaattcaag agtagaatta tcaaaggcag aagaaattat
    27841 gagacgaaga ataaatgaat ctcatatggt aaatggagtg actataatag acacgaactc
    27901 tacctatata gaatctgatg ttataatagg taatgatacc ataatatatc caggtgttat
    27961 gttacaagga aaaacaaaga taggttcaga ttgtataatt ggaatgaata catctataac
    28021 aaattcagaa ataggtgatg gtacagaagt aaaaaactca actataattg atagtaaagt
    28081 tggagaaaat tctactgttg gaccatatgc atatctaaga ccaaagagtg acttaggaaa
    28141 taatgtgaaa ataggcgatt ttgtagaagt aaaaaatgct attatagaag atggctcaaa
    28201 agcatctcat ctttcttata taggagatgc acatgtcggc aaaaatgtaa atattggatg
    28261 tggagtagta tttgtaaact atgatggtaa aaataaattt aaatcaatag taaaagacaa
    28321 tgcgtttata ggttcaaatt ctaatttagt tgcaccagta gttgtagaag aaaaaggata
    28381 tatagcaaca ggttcaacaa taacacataa tgttccagat ggtgctttgg caatagcaag
    28441 agaaagacaa gttattaaag aaggttgggt agaaaaaaag aatcaaaaag acaatcaaag
    28501 taagtagtta tgtagtttat tattttggct aaaaatttag ctcgaaatta ttataaatta
    28561 tattcattag tattttaaaa ttttcaggag ggttacataa atgaatacta gcggaagcga
    28621 gattaaaatt attgcaggta attcatcgaa agagttagca caaaaaatag ctgactatat
    28681 aggtgtatca gtactagatt gtgaagtagg tacatttagt gatggtgaaa tatgtgtaaa
    28741 catgaatgag acagtaagag gttgtgatgt gtttgtagtg caatctacta acagcccagt
    28801 aaatgataac ttaatggagt tattaatctt aattgatgca ttaaagagag catcagcagg
    28861 tagaataaca gcagttattc cttactatgg atatgcaaga caagatagaa aggctaaggc
    28921 aagagatcca atcactgcta aattggttgc aaacttaata actgctgctg gagcagatag
    28981 agtattaaca atggatttac atgcagctca aatacaagga tactttgata taccattaga
    29041 ccacttacta ggtggaacaa tattagcaaa ttattttaat gaaaagaaaa tagaagattt
    29101 agtagtagta tctcctgact taggaagtgt tactagatca agaaaatttg ctaatacttt
    29161 aaatggagaa gttccaatag ctataataga taaaagaaga ccaaaagcta atgtatgtga
    29221 agttatgaac ttaataggtg atgttaaagg taaaaatgtt atactattag acgatatgat
    29281 agatacagca ggaacaatag ttaatgctgc aaatgcactt aaagagtttg gagcaaaaga
    29341 tgtttatgct tgttgtactc atggtgtgtt atcaggccca gctattgaaa gaattgctaa
    29401 ttcagagata agtgagttaa tagttcttga tactatacaa cttcctgaag agaaaagaat
    29461 agataagata aagataaaaa cagtagctcc tttatttgga gatgctataa gaatgatatt
    29521 ctctaatgaa tcagtaagta aattattcta atttattgta tttatgagag ttgtttaaaa
    29581 ggatataagc cttttgagca actctttttg atttacttat ggaatgttat ttttctcttg
    29641 ttagaaaggt atctattatt gtagaaagag attatagttt aaaatttatg tatatttaat
    29701 caaaataaat ttaataaaag atatattatt caaaatatta tgaatataaa aaatattaca
    29761 aaaaagtatt gaaaaaattc agattatgta gtattatgta aatataaata aagaaagagg
    29821 tgtttccaat gggaaggtta gaagatgaac ccctaataat taaatgattc agtcacaatc
    29881 taaagtgaat ataaaaatct attgaaagtt tatttataag aattgaaaat agtatctatt
    29941 ctatctttag tgtttgtgag agggttctgg attatataaa attactgtaa agaaagtaat
    30001 tttgcacaat aagcatatct gtaaatgaag agtttcgttt atataatgat tgtggctgaa
    30061 tcataactat aatagataga atgtttataa tagatgattt tataaaatac tatattgtaa
    30121 tagcttttag ctttcaaata aatattagca aaggatggaa atgacaatga taaaactaaa
    30181 tgataattta taaatatctc cttacgatat ataataattg tagggagatg tttctttttt
    30241 tgtatagtat aattttttct agaaattctg tttcaatatg taaaaagttg gtatatataa
    30301 atagtataaa ctgtgttgct aaaatatggt agatattata taatataagt ggatatgtat
    30361 atacattatg agttatataa ttttgaattt aataaaatag aaacgttgat ttatgttctg
    30421 taatgtgggc accttggagc atattgagtt agtggtgcaa ccggctatga aattgtattt
    30481 atttatagat actattattt tcatagcttt ttttatttaa aaaatggtta tatattagaa
    30541 ataaatttgg ttagtacgtt taaataattt tacttggatt tttaaccaga tatattataa
    30601 gcaagtatta attaaaaagt tgagggggaa taaaaatgaa gttaaaaaag aataaaaaag
    30661 gtttcacttt agtggaatta ttggtagtaa ttgcaattat aggtatatta gcagtagtgg
    30721 cagttccagc tttatttagt aatataaaca aggctaaggt agcaagtgtt gagtctgatt
    30781 atagttcaat taagagtgca gcattatctt attattcaga tactaataaa ataccagtta
    30841 caccagatgg tcaaactggt ttaaatgttt tagagactta tatggaatct cttcctgata
    30901 aagctgatat aggtggagaa tataaattga ttaaagttgg taataaatta gtattacaga
    30961 taggtaaaga tggtgaagga gttaccttaa cagaagcgca atcagcaaaa ttattgagtg
    31021 atataggtaa agataaaata tatacaggtg ttacaggaga taattttgga gagcaattaa
    31081 aagatactac aaaaatagat aataaagctc tatatatagt acttatagat aatactgtga
    31141 tggattcaac aaaatagtta aaacaatatt tttataaaaa tattgtaaat ttaatgaaaa
    31201 atataatata aaagacagga agaaaatctt cctgtttttt tatactattt tctttaatgt
    31261 tcaattatga atgatgatat aattgagata gtaaaggagt gaaacctgtg gctaaaaaag
    31321 ttagaatagg agacaaactg gtcgaaaaag gatatataac agaagaccag cttaaatggg
    31381 cattatcaga acaaaaaaac agtggaaaaa gactagggga atttctagta caagaagggc
    31441 ttatagatag taacttatta ataagtgtat taaaagaact cttagatata gaaagcatct
    31501 ttttagaagg aacagaaata gatacattag ctacaaagat ggttccagaa aatatatgca
    31561 aaagatacac tgtatttcca tttaaaattg atggaaataa aatatgtcta gccatgtcag
    31621 acccacaaga cagagaagca gttcaagatg taagacgtat gtctggtaaa gacgtagaga
    31681 tatttatatc aagcacagaa gatataaaca aagcaatagg tcatgcttat gcacattcag
    31741 aaataaataa ggcaatgact gagtacaaca aaaatagaac tggtggagta agagaaacag
    31801 taatacttga agaagatgta aatgctgctc caatagtacg attagtaaat aacatactag
    31861 aaaatgctgt tagaatggaa gcaagtgata tacatataga acaaagtgaa aattacatgc
    31921 gtgttaggtt taggatagat ggaatgttaa gagaatatat gaggatgaac tcagcaccat
    31981 ataaggcagt aatcagccgt atcaagataa tgtcagatat aaatatatct gaaaagagaa
    32041 taccacagga tggtagaatc tatttaaaag tagataataa acccatagac tttagggttt
    32101 ctacaatgcc aactaacaga gatgaaaaaa tagccatgag ggttcttgat aagagtaatt
    32161 ttatggttag taaagaagta ctaggaatag atgagcatgg ctctaagata tatgatgaat
    32221 taataaacac tccttatggt cttatattgg ttgttggccc tactggaagt ggaaaaacta
    32281 ctacattgta ctcaatgcta aatcaactaa atacagaaaa tagaaaccta ttaacaatag
    32341 aagaccctat agagtatgaa ttacctggtg taaatcaatc tcaaataaat gaaaaggcag
    32401 ggcttacctt cgctagtggt cttagagcat tcatgcgtca agacccagat ataataatgg
    32461 ttggagagat aagagatact gaaacagcag aaatagcaat tagagcttct cttacagggc
    32521 atttagtctt aagtacatta catgcaaata cagcagttgg agcaatttca cgtcttttag
    32581 atatggatgt ggaaagtttt ctgataactt catctgtttt aggtgtaata tctcaaagac
    32641 ttacacgaaa aatatgtgag cattgtaagg tttcatatga agcagatatt ggagaaaaaa
    32701 aggctcttgg tattgatgta aatgaatcag taactattta tagaggaaaa ggttgtgaaa
    32761 ggtgtaataa tactggatat aaaggacgtc taggtatatt tgaaatgctt gaaattactc
    32821 cagaaataaa agagttaata gattcatctg caaatcaaag agaaatttta aagatggcta
    32881 gaaaacaagg tatggttagc ttaaaagagg atatagttaa aaaggtttta aatggaaaga
    32941 caacagtaga agaaatgatt agaataattt tgatgactga ttaaaggatg atattatgaa
    33001 aagttttaaa tacacagtaa taaaagagga cggaaaaaag caaactgatg tgattgaagc
    33061 caacgatttt aatgaagcta gaaatctcct tagaaagaga aatcttagag ttattgaaat
    33121 caaagaaagt aaaaataaaa atataagatt atctagtaga aagagaaaaa aagacttagg
    33181 agctgaccag ataagccact tttgtagaca gtttgctatt atagtatctt ctggtataaa
    33241 tagtatttct ggattagaaa cattagctag aaggtcaact aacattacat taagagaaga
    33301 aattaatcgt atagtggcag aaataaaagt aggttctact attgcagatt caatgctttc
    33361 atcaaaatca aagtttccaa agttacttgg tgctatggta gctacaggtg aagctacagg
    33421 taaattagat gaagtattaa aaagtatggc ttcattttat gcaagtgaac acagggttaa
    33481 acaaaagctt agaaatgctg caacatatcc attaatagtt ttgatttctt catttataat
    33541 gatttttata tttacagcat ttatggtgcc taagatgatt aattcaatta caacagtagg
    33601 agcaactctt ccacttataa caagaattgt tatggggttt ggtatgttta tgaagaagtt
    33661 ttggataata gtacttttag ttattatatt atttatctat cagtttaaaa agtatctaaa
    33721 aacgccaatt ggaagagctc ataaagatag agttataaac aagatacctg ttttaggaaa
    33781 aggaataaac tgtatggtag ctacacggtt ttcaagagca ttgtatctat ttgtatcaac
    33841 aggatatcca ttggttcaag ggcttgatta cattatagat agtgtaaata acaccatggc
    33901 agaaaagatt ttagtatcag ctaaagacgg aataacaaga ggagaaggtt tagcagaaaa
    33961 tttagagaga tatacatatt ttgactctgt attggtacag atgatagcta taggggagca
    34021 gacaggggaa ttagagaata taagtaaaca gatggccgaa ttctatgagt atgaatccga
    34081 gatttattta aataggatgg catcaatgat agagcctgtt ttaataattg cagttggtat
    34141 tatagttgcg atactggttg tatcaatatt tatgccaatg cttagtatat atgatgctat
    34201 gtaggaggga aatgacaaat gaacaaggtt tatgtatcat attatggcga ttctatttcc
    34261 atagttgagg gcagatataa acacaataag gataagtttt atataaaaaa tcttaatgtg
    34321 ttttcaatag aggatattgc acaagatttt tctaaggaaa agtatgctct attgagatac
    34381 gcattagaaa atgttaagtt aaaatcaaga catgtagttt tttgtttaaa tacaagagat
    34441 gtaattttaa aaccccaaaa acttcctaat atggataaaa aggatttaga cggatttatg
    34501 aagctagaga tggacgaaat gatggctttg gagtcagatg aatatgtatt ttcgtatgaa
    34561 gtatctagtg aaacacctga taattcagat ggcgatgaat caagcttaaa tcttatcatt
    34621 ggagctatac aaaaggaaga ggtaaatgca attgtagaga taatacatga atttgattta
    34681 atattagata gaatagatac attatcaaca gcttacttaa gaatgcttaa aaatttagat
    34741 tacaatgata taatggtaac taatataagt gacaatagca caattataaa tatatacaag
    34801 aaagatactt tatttattag tgataatata cctataaaga taactgctaa agatatggac
    34861 atgcaattat taaatgtagt agaagaatca aaaggtctta tgaattacta ttcgtcaaga
    34921 aactttggta aggttacaga tactatatta atattaggaa aaaggtattc caataaatta
    34981 atttatgaaa cttttagctc tgcattttca agctatgttt ctcaaggtct tactgagata
    35041 atggatatat ctgatatgat aactggagat atagatgaag atgatataaa ttcaattgta
    35101 gagcttttag gaagtatgat agaacctaaa gggaaaagag attttgaaaa tataaacttt
    35161 ttaccaatgg atatacttag aaaacagcta aaagctaaac agatgaaaaa catactgaaa
    35221 attgctccag tagttatttt gattcttgct ataccttatt tatgtttaat tttttcaaat
    35281 aatttagcaa acaaggaact tgaaaatgtt aatgctgaaa taagaaatat tgaatctgca
    35341 tattatcaga ttggaaatat agaaaaaatg atacagagta aaagcgaaga aataaaggta
    35401 tatgatatgt taattggaaa aaaggtaaag tgggaaaatt tgttggatga tatagataaa
    35461 aatactccaa gtaaagttga gctaacaagt ttatcaacga cttatcaaaa tcttggagct
    35521 aataataaag ctgataactc aagcagtaat aagactacaa cagataaatc aagtaacaat
    35581 gaaacaaaat caaatacgaa aagtgatagt aatggagata aaacaaataa tgatttaaat
    35641 gaagataaga ctacaaatgt gtcagaagca ttaactggaa atagtgagac taatagtaat
    35701 aacacagata aagatgataa aactccattg tatgataaga taccaaatgt tataaacata
    35761 gaaggaaatg ctaaagattc ctcttatgta ggtcaatttt tatataaatt aaagggattg
    35821 tattatttca aggatgttaa attacatagc ataaaaagta atgcagaaga ttctacctat
    35881 acatttagta tgacattata cctgaaagaa ggtgtattaa ctaatgaata aagatatatt
    35941 taaaaaagat ataaaagata tatttaaaat ggaagttagt ctaaaagggg ttcttataaa
    36001 ggttataatt ttattatcta ttttatcata tggttacttt ggactttacc ctcaatatca
    36061 gaaatatatt gttacaaaaa attctgtaaa acaagctact gaaaaattaa atatatataa
    36121 agagaaaact gcacttatgc caaaatatga aaaacaactt gaagaagttg aaagtgagtt
    36181 aaaagaaaaa agcaaaaatc ttttatatga tatgcaagat ggtctttttt taataggttt
    36241 agataaaaaa atgaaggctt ataatattga cttaactagt tatgacgttg gaaatgttag
    36301 agaatacgaa catttttatg gtgtatcaac aacaataagt gttagaggtg attatagaaa
    36361 tgtcaaaaaa ttaatggctt atttagaaga acaaaaaaat gttactcaaa tactagatta
    36421 tacaatgact tcatatatag aaccagaaaa agaagaggaa gaaacaacaa acaataagga
    36481 tttaattaaa aatgtgaaca taaataaaga tacaaaaata tactgggtgg aaggcgaaaa
    36541 taagtggcat ttatataagg attgtccatt gataaaagag ggagagattc taaaaaatga
    36601 caaactttta gataggtcta ctagttatct atgtaatact tgtgtactta gagctgcaac
    36661 agaaaaagaa gcaaaaaaag aagtcgtagc tccaaaggca gaaggtgtag tagatgctac
    36721 atttaaattt ataatgtaca ctaaagagaa tactacaatg atacttgata cagataatcc
    36781 atcttcatgg agaccgggaa aatataatcc atttaagtct agtgcgaaat aaagctaagt
    36841 aagctttaaa gataggtgat gagtttgtac aaaaataatg aaaaaggtct taccttatta
    36901 gaagtaataa tagctgtttt tatactgaca atagttttaa gcatttctta taaggtgttt
    36961 aatggtataa catcagcagt aaaaaagcaa cagattatta cagatgctca agtaaatatt
    37021 aacctaatta ataagtatct aaatagagat ttggaaaact gtaaagagct aactaaaact
    37081 ggttcaggta gtaattatga atataatata gagacgccag ataatattgt aaaatatgaa
    37141 gtttccatag aaactaaaaa aaatacagag gtatattctg taacaagaat cgaaaaaaat
    37201 acaattgata cagaaaatga agttagagaa gagataatct ataatcaacc actagttcaa
    37261 aacaataaag aaatgaaaga aacaccattt aaaatagaaa agcaaactga taaatctatt
    37321 tatactgtaa gtatattcta taatgaatca gttcaagaag gtcataaaaa tagcaattta
    37381 aataacaaga cttatacatt tgatgttatg tcgagaatag gataataaga atttattaaa
    37441 aataagtagg ttgataaaat atgagtaaaa agaatagtaa aagaggattt tccttaattg
    37501 aagtgttagt agctatggct attatgggaa ttatactatt tgcgtttttt aatattatca
    37561 atactaataa taaagcaaat attaaaaatg acacagatat aaattcctta aactatgtcc
    37621 aaagtgaaat agaaaatcta agagagaaga taaaaagtgg agaatttgat tttgatagtt
    37681 tagataaaat ggaagatggg actgtcgtat atgaaaaatt aatagataag tcaaaaaaaa
    37741 ttgtgtatga taaagttctt agtgagggta acgtgagctt atatgatact ccatatgaaa
    37801 agattacaac aataaaagat gaagatggta atttaatcga taaagaaaat attacaaata
    37861 agataaagac tattgtagaa gataaaagtg gtcagatata taaaatagct gtaactggga
    37921 aaagcatgaa tgactattca agtaaaaaag aagttaagat tgtaactgaa atatttaaag
    37981 ataaataatt ttacttgggg gtgagatttt gaggaagtgg aataaattta aaagtgaaag
    38041 aggggcagct ttagttttag ttctggttgt agtagcatta ctttctattg ttggattgat
    38101 gttttcaaat cagatagcca atagaataaa atctacaaag actactaatg agggtataca
    38161 agcaaagtat ttagcagaga catgtgtgga aaatagtatt gataaagcat atgaaaaatt
    38221 gtatgatgag cttgagaaaa tggataatga gtttaaaagt gaaaatcaac aaaaatccat
    38281 atctaggtca aaattaagaa atatatcaga tgaagatttt aataatcaaa atgaagaaaa
    38341 tcttgaagta gaaagactag gatatatgaa taatataaat ttctatttaa acaaagcttc
    38401 ctcagatttg gaaaaagcta gtatagaatt gaaaaaatta tatgatttag atatgttgga
    38461 ttacagagac attgaatatg tagatgaaaa tattatttca catagaaatt ctattttaga
    38521 tatttgtaag aattatactt ctggagatat tagtaaaata aatgaatata ttctggatga
    38581 agatataaat tcaactacgt tagttgaagc aaagttagta aataatgata ttcttttaaa
    38641 aatgttttta gaagaaaata aaattgaaaa tgaacattta aattcagcgt tttcatacac
    38701 ttataaggca ttagataaaa tttctttggc gatgcaaaat atgattgagt ataggcatac
    38761 atttcatata gatgagcaaa aagtagaagt atctaatggg attccaaatt ctcaacaata
    38821 ttatgaatta atacaaaatc ctataataaa tagtaaagag tatagctgga atagtaaatg
    38881 ggatacatta gaaaatctat tggaaacttt accaaatcaa actcaaggtt ttaattcttt
    38941 aagagttcat ttgagaaata atgtaagaaa atttgaggag ttaagcgata atatatctag
    39001 tggtaaaaaa aatacagcaa aaaatttctt aaagtataaa gagttattgt atgaaatatc
    39061 agaccaatgt aatcaactaa aaagtatgtc ttatgagaaa atacctgtta aatatgataa
    39121 catggccttg ataacaactt ttgactatat acaaaatgag cttttagcag agataaaatg
    39181 tagattaaaa gaattaaaac ctcaagaagt tgataaaaca gaagatatta ctataaaaat
    39241 acctttttat aaggctgact acgacatgac aaaagaagga tggcctaaat taaaagaaaa
    39301 tggttcaggg gcggagttaa gcttaatggt aactggtgat aaagatggaa taaaagaagt
    39361 ggaagttaca gatagtaaaa aaaatattat tggtttaggt gttgaagaaa attcaaattc
    39421 aaagtataaa gttgaagcta ttataaattt taatctaaat atagatacaa atatagtcgg
    39481 aaattatgat ataaaagata aaattttgat taatcatgac ataagttcat acaaaaaagt
    39541 aaactagata taataagtaa cttagtgtga ataaataata aaataatttt attatttact
    39601 actaaaaaaa taagtaaact aaaaaaagat atggagatta aatattatgt atatttatga
    39661 tttattagag caaggtataa gactaaacgc atcagatata cacataacag ttggaacgaa
    39721 tcctgtagct agagtaaaag gtggatttgt aaaactaagt gaacagatat tgacaccaga
    39781 agtaacaatg caaatggcaa aagacatagc aggagaatct atgtttaaag taataaaaga
    39841 acatggagaa gctgattttt cagcttctct aaaaacaggg gaaagattta gggtaaatgc
    39901 atataggcaa aaaggaaatt acgcaatagc aataaggact ataacagcag aaattccaac
    39961 atttgaaaaa ttaggtcttc cagaaaatat aaaatctttt actgaaaagc ataaaggatt
    40021 agttttagtt acaggtccaa caggaagtgg taaaagtaca acacttgcaa gtatgataaa
    40081 cataataaat gaaaaacaac aaaaacatat aattacactt gaagacccga tagaatatgt
    40141 acatcatcat aaacaaagtt tagtaaatca aagagaagta ggaactgata cagaaagttt
    40201 tcattcagcc cttagagcta ttttgcgtca ggacccagat gtaatactaa taggagagat
    40261 gagagaccct gaaactgttt caatagcatt aacagcagca gaaacaggtc acttagtatt
    40321 ttcaacacta catacagtag gggcagctaa gacaattgat agaatagtag acatgtttca
    40381 accatcccaa cagcaacaaa taaaaacaca gttatctaca gtctgtgaag gtgtggtatc
    40441 acagcagtta cttcctacag cagatggaaa aggcagaata gcagcaattg aattgatgtt
    40501 tgctactcca gcaataaaaa atctgataag ggaaggcaaa acatatcaaa ttccaaacat
    40561 gatacaaact ggagttaaat caggtatgaa aactatggac caagatttaa tggaacttta
    40621 taaaaatgga aagattacaa aagatatggc acttagtagg tgtactgacc aagagtttat
    40681 gacaagaatg ataggtggag taaactataa tggatattat aatcgttaat ctatatgtat
    40741 ttatagtggg tatagtgttt ggaagcttct ttaacgtctg catttttagg attccagaag
    40801 gtatatctat ttctagacct ccctcccatt gtatgagttg taatactaga ctaaagccaa
    40861 tagacttaat accagtgcta agctatttaa taagtggcag aaagtgtaga tattgttatg
    40921 agaaaatttc tagtagatat gctatagtag aattaattac aggaatttta tttttaatag
    40981 tatttatgtt atatggaata tctacatcaa ctgtttacta tttggtactt gtatctttac
    41041 tgattataat tacatttata gatattgacc actttataat accagatgaa atactgattt
    41101 ttggagctat ttttgctata atttttaacc ttttatttaa agaaattcca gttaaggatt
    41161 caattatagg tttttttatt tgtggaggaa gtgtctggct tatagttctt ttaattgaat
    41221 ttgtaataaa aaaagagtgt atgggtggag gagatattaa actatttgca atgctaggtc
    41281 tttacatggg tgttaaaaat agtcttttga cagctttact aagcgtctat gtgggagcag
    41341 tctatggaat ctgtgtaata attataagta agacaaaagg aaaggaatat aattctatta
    41401 taccatatgg tccttttata tctgttggag cattaataac aattttatgt ggaaaacaat
    41461 tactcgaatt ttatttttct atgattacat agataatagt caagctaaat caagttttaa
    41521 tttaaaaaaa tgaattaaag tattcaataa ggacaatatt attattaacc ctattactaa
    41581 agtgctacaa actatggagt atataataat aatttcctta ttttttgcac atttgataaa
    41641 taaatctcta tgtgtttttt gtgatagaga aaagaaaaac ttatataata cgttttttat
    41701 ttacataata actgtagttt tatctgtatt aatatatcta aaatttggaa ttagtgtaga
    41761 atgtgtacaa tatatggttt taattccatt tctaataatt atatccattg tagattacta
    41821 cacaatatat gtatatgata taacaatagt tagtggtata atagttcaag gtataatttt
    41881 tttggtcttt tgcaatatag ttcaatttga ttatataaat catatatttg gactagtgat
    41941 aggctttatt ataccttata ttattgctaa attaacaaaa ggattaggct atggagatgt
    42001 aggtctctat agcttatgtt gctttgcatt gggaaataat tatgggtttt atgtgatagt
    42061 tttatcattt attttagcgt ttttgttttt tattatttta tacataacta aaatatttaa
    42121 agatatagat ataaaaaagc aaattccttt tacacctttt atttccttag caacaatttt
    42181 aataatgttt acagagtata atatatttaa tttttattat agtttgttat acaaatttat
    42241 ataacaggag gtaagaaatg tacgtagtag tagggttagg taatccagga aagaagtatg
    42301 agaagactag acataacgtt ggatttgatg tgatagatat tcttgctaaa gaatacaata
    42361 ttagtgttac taaaataaaa cataaagctt taattggtga agggagagta ggtactgaaa
    42421 aagtattatt agttaaacca caaacttata tgaatctaag tggagaaaca ttaatagata
    42481 tatataaata ttacaaggtt gatttaagta atatagtagt agtatatgat gatatagatt
    42541 tagaagttgg aaagatacgt ataagaaaaa aaggaagtgg gggaactcat aatggcatga
    42601 aatctataac taagtgccta ggttcaaatg actttccaag agtaagagta ggtgtatcta
    42661 agccagaagt tggtcaagac ttagcagatt ttgtactttc tagatttaga aaagaagaat
    42721 ctgataacat aaatgaagca ttagaaaaag cagcatatgc tattgactca ataataagag
    42781 aaaatataga tatgtctatg aacaaataca atggatagtg agagggagat ttaaatgaat
    42841 gatgtttttt tatatccttt gcaaaattca aaagagtata aagatataat aaattgtata
    42901 aaaaatacaa aaggttcatt attggttaat ggacttttac cagtacaaaa acctcatata
    42961 tcttattcta tatttaatga tttatcacga caaatgattt ttataactag tagtgattta
    43021 gaagcaaaga aagtatatga agatttaagt ttttatattg aagataaggt tgaatattta
    43081 ggttttcaag atatttattt ttatcacttg gatgcaaagg acagaaatga agaagcaaag
    43141 aaattaaagg tattgttaaa actagcaaat aaagaaaaaa taattttagt aacttctatt
    43201 gaggcagttt taagaaaata tataccaaaa caagttttgc tcgatagtgt atctcattat
    43261 aaggtgggag ataacttaga cttagaaagg ttaactgaaa aattagtttc attgggatat
    43321 gaaagagttt caaaaataga ggggtttggt caatttagta taagaggtgg aattattgat
    43381 gtattttcac ttgaatatac aaatccaatt cgtatggaat tatttgatga tgagatagat
    43441 tccatacgaa cttttgacgt atattcacaa aaatcaattg ataaattgca acaattctct
    43501 ataactccat ctagggaatt tatttatcca gaaaaaacta cagatgcatt agttaaacta
    43561 aaaaaagaaa caactaaaaa tactgatgaa ggtacatttc aaaatataga ctatatatcg
    43621 agtaagactt attttgaagg tgtagaaaac tatatagatt atatttatcc agaagaaaac
    43681 aaaagtatat ttacctatct agcagatgat gcaatagtat ttattaacga tataacaaga
    43741 cttaaagaaa gatgcgaaaa ctatataaat gagtttagag aaaattataa actaaatctt
    43801 gaaagaggtt tggctattaa aaaccaaggt aaattgttat atcactatac agatttagag
    43861 tacttagtaa aagacaagtc tgtggtatta aactctctat tgccaaagtc tataaataat
    43921 ttttctataa aatctataat aaattttgaa agtagagaag ttcctacctt taatggaaag
    43981 gtagatttgc ttgtagaaga attaaatcgg ctgaaatata atggatacaa aataatttta
    44041 gcaacaaata ccttagaaag agcaaataaa ctaggaaaag atttattgga caaaggctta
    44101 gaaacaacca tttctaaaga tagagatatt gagattaaat cttcacaagt tataattgta
    44161 cctgcacaca taaacagtgg ttttcagtat aaatctataa agtttgttgt tataacagat
    44221 aatgaaatga taggtgttta taaaagagca tctaaaacta ccaataaaaa agttaaaaaa
    44281 ggaaaaaaaa tagaatcatt tttagattta agtgttggag actatgtagt gcatgaaaat
    44341 agtggtgtag gtagatacac aggaattgaa caaattacag tcaatgctat taaaaaagat
    44401 tatatgaaaa tagtatatca aggtggagat aatctatatg tacctataga ccagatggac
    44461 aaagtacaaa aatatattgg tgcagaagta gaaaaagtta agttaaataa gcttggaaca
    44521 aatgagtgga caaaagcaaa agcaaaagtt aaaaaagaaa ttgaagatat gacaaaagat
    44581 ttgattgagc tttatgcgaa acgtgaaaaa atacaaggtt ataagttttc aaaagacaca
    44641 ccttggcagg cagaatttga atctttgttt ccatatcaag aaacagagga ccaattaaag
    44701 gcgatagaag aaactaaaaa agatatggaa tcaagtaagg taatggatag actagtatgt
    44761 ggagacgttg gttatggaaa aacagaagta gctattagaa gtatttttaa agcttgtatg
    44821 gaccaaaaac aagttgctgt attggttcca acaacaatat tggctcaaca acattacaat
    44881 acattcaaag agaggtttga aaattatcct ttgagagtag aagttttaag tagatttaaa
    44941 acaccaaaac aacaaaaaca gattattgaa gatgctaaaa aaggattagt agatattttg
    45001 attggaacac atagaataat atccaaagat ataaatttac caaacttagg tcttgtagtc
    45061 attgatgaag agcaaagatt tggagtaaaa cataaagaag ctttaaagaa aattaaatct
    45121 acagtagatg tacttacact ttcagcaact cctataccaa gaacattaca tatgtcttta
    45181 agtggaataa gagacatgag tgttatagaa gaacctccac aagaaagaca tcctgtaata
    45241 acatatgtta cagagagtaa ggaaagcgta attcaagatg agatagagag agagttaagt
    45301 agaggtggac aggtattttt tgtatacaat agagttgaac atattgaaga gatggcaagt
    45361 atgattcaaa aactcgtacc agatgctaga gtggctgttg cacatggaag aatgacttct
    45421 aaatcattag aaaacataat cctaggattt ttaaataaag attatgatgt actagtctgt
    45481 actacaataa ttgaaactgg tatggatata tccaatgcaa atacaatgat tatatatgat
    45541 gcagataaaa tgggcttggc gcaactttac caattgagag gtagggttgg aagaagttca
    45601 agacaaggat atgcatatct tttatatgaa aaagataaaa ctctaagtga gatagcagag
    45661 aagagattaa aagctatcag agaatttaca gagtttggtt ctggttttaa aatagcaatg
    45721 agagaccttg aaataagagg cgctggaaat attttaggtt ctcaacaaca tggtcatatg
    45781 gcagttatag gttatgattt gtatgttaaa atgcttaatg atgcaatcaa aaaagttaaa
    45841 ggagaaccta ttgtagagga aattgatgtt gaaatagatt taagtgtaaa tgcatacatt
    45901 ccagataatt atatcaaaga tgagttaatt aaaattgaaa tgtataagaa aatagcttct
    45961 attgaaaata aagaagacat gttggatata caagaagaac ttgaggatag attctctgat
    46021 atacctaaac cagtccagac acttcttaca atagcttata taaaatcgtt atgtaagata
    46081 ttgaaaatag aaaagataag acaattaaaa gatgaaatat tattagttcc aataacaaag
    46141 tatagaacta aacagaaaat aggttataat atagttacag aattagaaga attattagaa
    46201 aaaatgtgca aggtaaaata acttgtaaat ttaagaaggg atgttttaaa tttgaaaaag
    46261 gtaataacat tggtaatagc tatgattttg gtagtatctg tgactgcttg caattctagt
    46321 aaaggagaaa ctgtggcaac agttgaaggt acaaagatat catcagatga atttaaaaaa
    46381 actatagctc tttataagga ttctatggag caaacttatg gaaaagatat atgggataag
    46441 gaagttgaaa agggtgtaaa atacaaggac aagtttaaag atttaattct tgaccaactt
    46501 ataactacag aagtaatata ttctcaagct aaaaaagata acttacttcc taaaaaggag
    46561 gatgttgaaa aaagctttaa agaattaaaa gatgctatgg ggaaagatga aaaatataaa
    46621 gaacagctta agaaattagg gatagatgat gagtttttaa gagaccaaca agagaaagat
    46681 ttagcaatgc aaaactatca aagtaacttt actaaaaaga ctaaaatatc agatgaagaa
    46741 atgaaaaaat actatgatac acataaagat gaatttaaaa aagatgaggt agaagcttct
    46801 catattttat tgaaaacagt agatgacaat aacaagccac tttcagctaa ggaaaaagct
    46861 gaagctaaga aaaaagctga ggaggctctt aaagaagtta aatcaggtga ggactttgca
    46921 aaagtagcaa aaaaatattc acaagatgct tcagcaagtg atggtggtaa attaggattc
    46981 ttttcaaggg ggcaaatggt tgctgaattt gaagacgctg cattttctat gaaaaagggt
    47041 gaagtatctg atttagttga aactcaatat ggataccaca taattaaagt aacagacaga
    47101 ataaatgagc aaacatcatt tgaagatgct aaagaaacta taaaagacca actattaaaa
    47161 aataaatatc aagagcaaat agaaaaatta actaaagaag ctaaagtaga aaaagatgaa
    47221 aaagtaataa ataaaatcac aatctaagac ctaaaaaaga gtaatatgct taaaaaagct
    47281 atatctggat aagatatagc tttttttgta tatttttctt aacaatggta aaaataaact
    47341 taaagtaatt tatggaggga ttaaaaaata tgaaagcaac aggtatagtt agaagaatag
    47401 atgatcttgg aagggtagtt atcccaaaag agataagaaa gacattaaga attagagaag
    47461 gagacccttt agagatattc acagcaaaag atggagaagt catacttaaa aaatactctc
    47521 caataggtga attaaatgaa ttttcgcaag aatatgctga aacattagct gaagtactag
    47581 gatatggagt gttgataaca gacttagatt ctataatagc tgtgtctaag cttcctaaaa
    47641 aagattataa agaaaaaagt ataagtgatg agttagaagc aataataagt gaaagaacag
    47701 taaagtattc aaaagataaa aacattttac cattattcaa agaagaccaa aaagaatata
    47761 ctagtcaagt tatcatgcct ataattagtg catctggtga ctgtataggt tcaattgtag
    47821 ttgtttcaaa ggacaaagat acaattgcag aaagtgaaga aaaatcttta aaaattgctg
    47881 ctaacttttt aggaaaacaa gttcaataat tttatcataa agacctttta catgaaggtc
    47941 ttttgaagtt tttgtgtaaa atattgaaca tagcattaaa aatatgttat attaaagttt
    48001 gttatataaa cagtgtggag gttatgttat gaacaataac aaaaataaag actcctttct
    48061 aaaaggagcc cttatacttg ggctagcagg tgtaatcgta aaaataatgg gtggattttt
    48121 taggattccc cttggaaaca tgattggttc agaagggatg ggatactatc aggctgctta
    48181 tcctgtgtat actctatttt taacattagc tactgctgga tttccaacag ctgtggctaa
    48241 gttggtttcg gaaaaagttg ccattggaaa ttttaaaggt gcaaataaga tatttaaggt
    48301 atcacataca gttttattta ttactggtat aatatcattt tgtatattat tttttggagc
    48361 cgactacata gtaacaaaca taatgaaaaa tccaggtgcg ttatactcta tgaaagctat
    48421 tgctccagca ttactatttg ttccagcaat gtctgcatat agaggttatt ttcaagggag
    48481 acaagatatg actaaaattg ctgtgtctca agttgcagag caatttttta gagttgtatt
    48541 aggtcttact ttggcttact tgcttatgaa gagtctaggt cagacttttg gtgcagcggg
    48601 agctatatca ggagctacaa taggttcaat agcatctatg ctttacttaa tgtttgctta
    48661 tatgctaggg agaaaagagc gtagagcaga gatagatgca agccaaagat ttaaagatga
    48721 gagagtgtct tatattttta aaaagctttt aactgttgcc attcctataa caataggagc
    48781 atcagtaatg ccacttgtaa atatgataga taatgttatt gtaataagaa gacttatgga
    48841 agcaggcttt acatacaaag tggcaaattc aatgtttggt caattaacag gtatggcaat
    48901 ggccacaata aatttaccag cagtcataac aactgcaatg agtatgagct tagttccagc
    48961 tatttctaaa gcatatgcat taggaaataa gtcaaaagct agaaaagata ctaagagtgc
    49021 agttaaggta actttactta tagtattgcc ttgtgcgttt ggtatggctt ctttagcaat
    49081 accaataatg gggcttttat ttccacatga accatcttct gtaggaacta ttttgtttac
    49141 tcttactcca tgtgtattat ttttaggatt aatacagaca ttgactggta taattcaagg
    49201 aatgggaaaa ccaatagtac ctgtaattgc tttatgtgtt ggtatgctat gtaaaattgt
    49261 aataagttat actttaacag gtatcccaga tattaatgta ctgggttcag cctttggtac
    49321 agttacagcg tactttgtgg cagccatgat taacttacta tatgttaaaa aacacatgaa
    49381 tgtaaacttt tctaaaaaag aatttataat aaagccattt ataacagtta tgacaatgtt
    49441 tataatggtt aagttgagtt atggtgcttt agttggattc ttaggaaaca gcatatccac
    49501 aataattgca atatgtatcg gtggaattgt atatgtagta gtaatacttg gaataggtgg
    49561 aattaaaaaa gaagagattc taactatgcc aaaaggtgat aaattatata aattgttaaa
    49621 aaaagttaaa cttataagat aatataggaa tatatatgca aataagggaa atactataca
    49681 aatagtaaat ctccttattt gtatagtaat ataaaaataa tgtgaaattt gctaatagga
    49741 gtgatgttat gggtaagata agtattgtag gtcttggacc aggagactat tctcttataa
    49801 gccaaggtgt gttagaatct ttaaaaaata gccctaaagt tttttttaga acagagaaac
    49861 atccaataat tgataaactt aaagaaacta tacaatacac ttctttagac tacttttatg
    49921 aaaaagagga aaactttgac aatgtttatt tgaaaatatc tgaatttatc atagaagaat
    49981 ctgcaaaggg tgatttagta tatgctgttc ctggtcatcc aagagtcgca gaaaagactg
    50041 taagtataat agagagattg gccaatgaaa agcacatagc agtagaaata gtgccttcta
    50101 tgagctttgt agacgctatg tttaactatt tggctataga cccatctgag ggatttaaac
    50161 tggtagatgc ttttgaaata gataattcat atatagactt ggatacaagt atgataataa
    50221 ctcaggtata tgataaattt atagcatcta atgtaaaatt aaaacttatg gaatattatg
    50281 actataatca agaagtatgt atagtaaatg gagcaggtgt caaagattta gaaaataaaa
    50341 agtttataaa gctttgtgaa ttagacagaa atgaaaactt ttttgactat ttaactagct
    50401 tatatatacc caaaagttct aaaaagatgt ataatacagt acatgactta gaaataatag
    50461 ttaatacact tagaagccca tctggatgtg aatgggataa aaaacaaaca catcaatcat
    50521 taaaaaattc tgttatagag gaagcatatg aactttgtaa tgcaattgat aataatgata
    50581 tagatgaaat ggtagaagag ttaggagatg ttcttttaca ggttatattc cattgtcaga
    50641 taggaaatga ggagggctac tttgatttaa aagaagtagt aaatggaata tgtaaaaaat
    50701 taattcatag acatcctcat atatttagtg gtgcaaaact agatatgtct aagtttgaaa
    50761 aaacttggga agaattaaag aaagaagaga aaggcgaaag tactataaca gatggcctta
    50821 gaaggatacc aaaacattta ccagctctta tgaaggctag taaagttcaa cataaagcag
    50881 cacttgtcgg ctttgattgg gacaatgtag aagatgtatt taaaaaaatt gaagaagaat
    50941 atcaggaatt acttgacgaa cacagggtcg ggaatataaa atacataaag gaagagctag
    51001 gcgatttatt attttcgata gtaaatctag ctagattttt agacatagac tcaggagaag
    51061 ccttgaactg tactacagaa aaattcataa atagatttga gtttatagaa aaaagtgcaa
    51121 tgaacttgaa taaaaaatta gaagacatga cacttgaaga gatggatgag ttttggaatc
    51181 aggctaaaaa acaataaaat tgtggaagga aatttgtcaa aaatctagaa cttttatcac
    51241 aaagatagaa gtctatatta taaacatttt taggaggtaa atatcgtgaa taaagctgaa
    51301 ttagtatcaa agatggcaga aaaaagtgga ttaacaaaga aggaagcaga agctgcgtta
    51361 aacgcattta tgagttctgt tcaagatgca ctagtaaata atgaaaaagt tcaattagtt
    51421 ggatttggaa catttgagac aagagaaaga gctgctagac aaggaagaaa tccaagagat
    51481 ccagagcaag ttatagatat accagcttct aaagcaccag ttttcaaagc tggaaaagga
    51541 ttaaaggata taataaatgg ataattacaa atcttgtgaa aaagtgtgga taaatttgcc
    51601 acactttttc tatagagcca aggaaggtga taattatgag attagataaa tttttaaaag
    51661 tatctaggat tataaaaaga agaactgttg ctaaagatgc atgtgataaa gggattgtca
    51721 ctataaatgg aaaagttgct aaatcttctt cagaagtgaa tattggagac acattagaaa
    51781 tacaatttgg agagaagaag atgaagttta agataaatga agtaaaagag catgtattaa
    51841 aaaatgatgc aaaagaaatg tacgaaattt tagaataaaa ttaatagtcc tctagtatat
    51901 taatagtagt attattgaaa tatttactgg ggggatatta tggaacagaa cataactttg
    51961 aaagatagat caaagctggt tatttcggga gttgagcaca tatactcttt taatgacaaa
    52021 agagtagagc tcaaaacttc tgtaggcgag atggtaattg aaggcgaaaa cctagatatg
    52081 agcaagttaa gtatagacga aaatataatt agcatagatg gaactataaa ttctatggta
    52141 tatgcaaagc ctaaaaagcc acaagagagt ttcttgaaaa aggtatttag atagatgata
    52201 ccttttactc aagatgtaag cattttttat gctactattt atggtggaat acttataggg
    52261 gtgttgtttg atttttatag agggctaaga ggaaatttta aattcatcaa ttattttgca
    52321 ataatatttg atgtattgtt ttggtttcta gctacagtta taatattcgt aacaataaac
    52381 cttacagaat tttttgattt aagatattat cattttgtgg ctttgtttat tggttttatt
    52441 ttatactata acaccataag taaaattgtt ttatcaatta tcaataaaat aattcgtttt
    52501 gtgagaaatt cttttaaaaa agttacacat tacatagtca gttttttaaa caatttgtat
    52561 tacgttataa tctattcact acacctacta tttgatatta tattttatat accaaacata
    52621 tttatagcaa caagaaaaag tataaaaaga aaatcaaata aaaaatcaaa gaacaagaaa
    52681 aaatcaaaac ctaagaagaa aaaaaataaa actaaaaaaa gggtgtagga aaaatgaact
    52741 taagaaaaaa attttcagga cagattattg ttatcagttt atttttagga atatcaattt
    52801 ttagtatgat gacaggattt gtatttgagt atacaaaagc taaggaatat aaaaaagaaa
    52861 tagcaagtct aaataaacaa ttaaaaaaga ctgaaataca aataaacgcc ttaaagaaag
    52921 atgaaaaatc atatgaagga gacttagagg atatagcaag aaaaagatta aatatggtaa
    52981 aaccaaatga aacagtttat gtagatataa atcgttgatt aaaacttgct aataagttta
    53041 cagatgtatt gattttaaaa tttaagattt aataaaaaag tcattcagtt aaggatggct
    53101 ttttgttttt attgaggagg agattttata atgaaagtag gagctataga tattgggaca
    53161 aactcaatga gattattgat agcagattat agagatggaa atttcataaa cagaaaaaaa
    53221 tttgttaata caactagaat tggttatggt gtggatagta aaggatatat aaaggaagat
    53281 gctattaaaa gaaatataaa agcactaaaa gaattttcta ataagtgtaa tgatgaaaag
    53341 tgtgaaaaaa tttattgtat ggggacatct gctcttagag acagtaaaaa tggagattat
    53401 tttgttaaac tagctaaaga agaaactgga atagatgttg atatagttac aggaatagaa
    53461 gaatcaaatt tgggatttaa gggcgtttta gaaggaatac aagatgatga tactattatt
    53521 gttatagata ttggaggagg ttcaacagaa tttattgtag gtgactcaga aggaattaaa
    53581 tttaataaaa gtgaaaatgt aggtgctctt aggatgacag agagattttt gaagcatgat
    53641 attattgaag atgaagagct tgaagctatg agttcattta tatatgatga gattgacaaa
    53701 acgttaaatc atataaaata cagaggatta aaaactctta taggtatagg tggtacgatt
    53761 acatcattat cagcaatgaa tcaagaatta gaggtttact ctatggaaaa aatacataat
    53821 agtaaaatac acaaaaaaga aatagaagaa attctacaaa aattaataaa gatgacatta
    53881 agtgataaaa agaacttaaa agggctacaa gaaaaacgtg cggatattat aactgctggt
    53941 gtaaaaatat tgaatataat aatggaaaaa ttagaaatag aagaaataac cgtaagtgaa
    54001 tacgataatt tggaaggctt aatatgtcaa aagtcaaaaa aaatgtatta atattttttg
    54061 atttttaaaa ccgattatga caaaaaaaat tactcctctt tgttacaatt cttaatataa
    54121 acaaaagagg aggttttttt atgcaaagaa gtgtagcagt tgtgaagaat aagactgtaa
    54181 aaccaaatgt cataaaatta ataagcggat atattgattt tactacggcg gcattcgctg
    54241 tgatgggatt tttacttagt aggtctatta tagtagactc tgtagctccc ttaggaattg
    54301 ccttttttat atgtgcatca aagattgata agtacaaaat acctgtattc atatcaacat
    54361 tattaggaat attgttatca tctaatgatt ttggaaatgt agcaaaatat gctgtgtgcc
    54421 ttacaatatt tatggctatg aataaaaaat taaaattatc agattcaatt gctaaggttg
    54481 catttatagg tgcaataata ctacttccaa tctccatagg acaagctttc ttttcaaata
    54541 ggtatgtgta tggtcttctt attgcaggag tagaagcaat aataatgttt atatctatat
    54601 atgtgttttc ttatggaata ggtttaatgg ccaatgtcaa caataggatg tctgtacgga
    54661 cagaagaagc tatatcaata agtttactgc taacctttag cataatggga ataggagata
    54721 tatccctgtt tggaatatca ataaggacca ttttatcgac tgtattgata ttactgacct
    54781 cgatagtagg tggagctacc atgggagcat ctagtggtgt aattattggt gtagcatcca
    54841 ttttaaataa tatgacatca gctatttata tgggaatata ttctttttca gggttaataa
    54901 gtggagcatt taataagata aataaatatt tctgtatact aggatatatt ctaagttgga
    54961 caataatata cctatatact tctggtatta cttctaatat gatgcaatta agagatatac
    55021 tattaggttg tttgatagta ttggtattgc cagagagatt gtttaataag attgaaaaat
    55081 taataaaaag taatgtagcc tcaaatgaaa tcgtatacga ttatattatg agaagcaaga
    55141 atttgactaa tagtcgattg aacagtattt ataaaactta tgacgacctt gcagatacgt
    55201 ttgataagat aagagaaaaa gacaaagtat tagaccagag agatatagct aacgtaatag
    55261 atatgattca taatgatgaa tgtaaaagtt gtagtatgag aagaatgtgc tgggaatcaa
    55321 gatttaatca tacatacact atgatatata acattcttga aaaaattgag gagaaagggg
    55381 agttaagtct aaacgatata cctaaaaatt ttagaaagga atgtatgaaa ccagagtcaa
    55441 tagtgaaaat atcaaatcac tattacaaaa tgtttgtatt agattatgat tggagtgtga
    55501 agttctcaga aagtagaaag ttaatagcaa atcagataag aagtatttca aaatcaatta
    55561 aatcgttatc tcaagattta gaaggtgaca taatgctaga tatagaaaag gaaaaaaata
    55621 tatatgaaca gctagaaaga tatgatataa cagttgataa agtaagttac ttaacaaaaa
    55681 gtaacagtga gtttgaaata tcaatagaaa agaaaacttg ccatgatgga tgtatgtgtg
    55741 aagataaaat cgtaaatata atttcagact tagtaggaga aaatatgtct gttagaaaaa
    55801 tagggtgtca ctgtttagga ggtaaatgta aggcaacatt cgttaaatct caaaaatata
    55861 aggctgttac agaagtttca gcaatgtcaa gggatggaca tattctttgt ggagacaatt
    55921 acacatacat ggagataaat gatggtaaat atatgatggc tataagtgat ggtatgggaa
    55981 aaggtaaaaa agcatatgaa gaatcttctg ccactattga tatactggaa aaaatgatag
    56041 atgcaaaaat taaagacgaa atagttattg atactataaa taatatgttg ctattaaagt
    56101 cttcagaaga gatgttttca actttggatt tgggaatttt agatttaaaa cgaggttgtt
    56161 tagaaactat aaagatggga gcgtgttcta cttatataaa aagagaggat ggagaagttg
    56221 acttaatatc atcatcatca ttacctgtag gtatattatc agatgtaaaa attgatagaa
    56281 aaaatgtaaa agttaaggaa ggagactatg taataatggt ttctgatgga attgtagatg
    56341 caggaagaaa taacaattta ggagataatt ggttaatata cttcttaaag aatatagaga
    56401 ctacaaatcc aaaagaaatt tcaaatttaa tattggatag agcattagag ttacaagcgt
    56461 tacaaatcga agatgacatg actgttttag ttacgaaaat atgtacaaaa taaggtttgc
    56521 aaaattatgt gtataagatg tggataactt gtgtataata tgttaataga cttttgaaaa
    56581 aagtatagtt attaacaaaa ataacatata aatcaacaaa atttgttgat aagtatggca
    56641 gaaatgttaa taaaatgtaa aaaaagaaaa aacaaaagct attatcaaaa gagattcatg
    56701 ttgaaataac taaatttcta tgtaaagaaa acctgtgaat atgttgatta ttatgtggat
    56761 aactattaat tcgatattta tttatatagt atgaataatt gaataatata tctaaaaaaa
    56821 gccatcctat tattaagtaa acttattgaa aggatggctt tttatgaata gaaaattgtg
    56881 caaagcaata atacctttat ttatttctat tttttgcatg ttaataataa gtataaaagc
    56941 tgaccaagga tatcaaaaga atggtgacag agcaattact gtcatgaata acaatgatac
    57001 tgaagatgat gctgaaaaaa aacaagaaat agactatgaa aaaacatgtt ggaacttgca
    57061 atctttgttt aaaagtgatg aacagtggaa aaaagaactt aagagttttg ataaagatac
    57121 taaagagttg aaaaattaca taggcaaagt aacaaaatcg ccaacacatt tgtcttttgc
    57181 cttaaacatt aaggaaaaac ttgatataag actaaataaa ctttctgcct atgtaaaatt
    57241 aaagcaagat actaataaaa attcatataa gtacttagat atgagtgata gcatgagtaa
    57301 atcctatggg aattatatgg ggatttgctc agatttagaa ttagaaatac taaaattatc
    57361 aaacaaagat tacaagaaaa ttatttcaaa taaaaatata aatagaaaat atggtgcata
    57421 tttaagagat ataagaagaa ataaagtaca ttatttggat gataaatcag aagatattct
    57481 aagcaaagta tcttcaataa gtagtcttcc aagccaagta tatgaattat ttagaaatat
    57541 ggatagaaaa actaatttga caccagctca atatgcaagt gaattagagt catcagatag
    57601 agaaaataga aaaaaagctt atcaagatga acttataact tacaatgata atataaatac
    57661 aattgcaggt ttaattactg gtcaagttaa aaagaatatt ttttattctc aggaaagagg
    57721 ttatgagtct tctttagaaa tgtacttaga atctgataat gtagatgaaa aagtatacaa
    57781 taatttgata aggactgtaa atggtaatat ggacagtcta cacaaatata tagatttaag
    57841 aaaaaaagta ttaaaattag ataaggttca ttcatatgat atgtttgtgc ctatggttaa
    57901 ggctgttgat aataatatta attatgaaaa ggcacaaagt atagtatatt cagcgttgtc
    57961 acctttagga aaagaataca atgatgtagt atataaagct ttcaatgaaa aatggataga
    58021 tgtttattca catgaaaata aagtaagtgg tggatactgc ttatctgttt atgaaaatca
    58081 tccatatata cttttaaatt ataataattc attaggctca gtttctactt tatcacatga
    58141 gcttggtcat gctgtatacg aatacttaag ctctaagaat cagaattatt ttaattcaaa
    58201 tccttctata tttactcacg aagttgcatc tacaacgaat gaagcattac tttacgagat
    58261 gcttataaaa gaggctaaag gcaatgatga aaaagcttat tatataacac agtacttaga
    58321 cttgataaaa gatactcttt atacacaaac catgtatgct gaatttgaaa aaactataca
    58381 tgagttagta gaaaaaggaa aaagtgtaaa cgcattagta ttaaatgatg tttggggaca
    58441 acttcttaaa aaatattatg gacaaagcta tgaattagac caattatcta aggtcggatg
    58501 ggctagaatc ccacattttt ataatagttt ctatgtctat aaatatgcta caggttgtag
    58561 tgcaggagta agttttgccc aagacatact aaaaaatggt tccgataact atatgagctt
    58621 tctcaaaaag ggaagttcag attatccaat aaacttgtta aaatcaagtg ggataaattt
    58681 aactaataca aagccaatag aaaatacaat caaaaaattt gacagtttag tagcagaact
    58741 tgaaaagcta ttataaacat tattataatc cacatggtaa atatatcgaa ttaatgataa
    58801 aatatactaa aagtttaaag tcctatcaag ataggacttt ttatttatta attagtggga
    58861 gatgattcta tgcaagttaa agttaaaaag gctgtaatac cagcagcagg tttaggaact
    58921 agatttttgc cagctacaaa ggcacaacca aaagagatgt tgccaatagt tgataagcca
    58981 actctacaat acataataga agaagctgtg gcctcaggga tagaggaaat actaataata
    59041 acaggtagaa ataaaaagtc tattgaagac cactttgata aatctgtaga attggaactt
    59101 gatttagaga aaaaaggtaa aaaagaattg ttagagatag tacaaaacat atctaacatg
    59161 attaacatac attatataag acaaaaagag ccaaaaggat taggagatgc aatttattgt
    59221 gcgagacatt ttataggtga tgagccattt gcagtaatgt taggtgatga tattgtagat
    59281 aatgatgtac cttgcctaaa acaactaaca gatgcatatg aggagtatag aactacgata
    59341 ttgggtgttc aaaaggtaaa tcaagaagat actaataaat atggcataat agaagcaaaa
    59401 aatatagaag gtagagttta taaggtaaaa gacatggtgg aaaagccaga gtcaggaaaa
    59461 gctccttcaa atattgctat tttaggtaga tatataataa ctcctgaaat ctttgatatt
    59521 cttaaggatt taccaccagg taaaggtgga gaggtacaac ttacagatgc tttaaaaata
    59581 ttatctaaga aagaagctat gtatgcatac aattttgaag gcaagagata tgatgttggt
    59641 gacaagctag gatttttaga agccactgtt gactttgctc taaagaaaga agaccttaag
    59701 gaagatttta taaaatattt gaaacatgta tgtagtgaat ttgataaaaa taacaatgtg
    59761 ttatacaata atacagatga aaaaatagat ttaattgaag tcaatgaaat cagagaactt
    59821 gaaattcaaa aataattaat gaaaggtgat gtatggtggc aaaatcaagt cagaaaagaa
    59881 ttaatagaat aatagctgtt gggattgtgg gaatccttgt attaactagt ataacagctg
    59941 ttttgagtat gattgcaact atgtaataag gtaaataaca gaagttgata tacataaata
    60001 taaaaaccat atataacttg atgtagttaa aaaattacaa tattttagtt atatatggtt
    60061 tttataattt ataaatgtaa aaaaaatttt ttataatagt tgcatatttt aaaagaaaat
    60121 attattataa gatataaata tagtgataaa tttataaaaa cgtgctaaga ttggacttga
    60181 aatacagtaa tatagtaggt aataatgttt taaattttat ttattgacca taatatataa
    60241 ataatgatat tattagactt aactgtttaa ataaaacttt tctttttcat gccttcaatt
    60301 ttcaaaataa gtatgtatat aaatgaatat atagatgagg aggatttttt tgattttaga
    60361 tgataaagta ttagaaggat taggtagtaa gaccttagtt gagctacgag agatagctaa
    60421 agaattaaaa ataaaatcaa ttactacata taagaaaaat gagttaattg agattataaa
    60481 ttccaaaagt aaaaatgagg aaaaaataaa cgaagagact aaagaaaaaa acgaagatat
    60541 taaagaagac ataaaaaata gaaaagaaaa tatagagcgt gaaagtatag aaaaagaagt
    60601 tgaatataag agccctacca aatcatacaa caagaaagaa atagataccc aaaatatttc
    60661 ccaaaaccaa gaaaatagaa atcaaagaaa tgattataat aagacaacaa gtgtaaatga
    60721 ttgtaataag ccatcaaata tatctaatag aatggtcaga aataataata aaaactatta
    60781 tatgcctaaa caagttgatg aatctaagat agtagatgaa tttaacacat caaaagagga
    60841 tgaagtagta ggtgtacttg aaattctgcc agatggattt ggttttttaa gaggttcaaa
    60901 ttatttgtct actgaaggag atgtttatgt ttcaccatct cagataagaa gatttaatat
    60961 gaaaacagga gataagatta agggaataac tagacatcca aaaagtggag agaaatttag
    61021 agcgctttta tatgttcaaa aaataaatga tgaaaaccct gacacagcta tacaaagaaa
    61081 tgcgtttgaa acattaacac caatatttcc agaagaacga cttacactgg aaactaatag
    61141 aaatgaaata gctacaagaa ttatagattt aatttcacct ataggaaaag gacaaagagg
    61201 gttgatagta gcacctccaa aagccgggaa aacagttctt ttaaaaagcg ttgcaaatag
    61261 tatagctaaa aatcatccaa atgttgaact tatagtactc cttatagatg aaagaccaga
    61321 ggaagttact gacatgaaag agtctattga aggagatgtt atatattcta cttttgacca
    61381 agtatcaagt catcatgtta aggttgctga gatggtatta aatagagctc aaagattagt
    61441 tgaacatggc aaagatgtag taattttact agatagtata actagattgg caagagcata
    61501 taaccttaca atatctccta caggtagaac tttatctgga ggtattgacc ctggtgcact
    61561 acatggacct aaaaagtttt ttggtgcagc aaggaatatt agacagggtg gttctttgac
    61621 aatattagga acagcgttag ttgaaactgg ttctaggatg gatgatgtaa tatttgagga
    61681 atttaaaggt acaggaaata tggaattaca tttagataga aaattagcag aaaaaagaat
    61741 attccctgca atagatattt acaagtctgg tacaagaaga gatgacttat tgcttgatga
    61801 tgaagaaaag actgctcttt ggagattaag aagagaaatg agtaataatt cagtaatgga
    61861 aattacagat aaagtcattg aacttataaa gagaactaaa gacaataaag agtttgtaaa
    61921 atcaataaaa aatttgtaaa atcaataata caaatgtaaa tgtagattat ataaagtaat
    61981 agaaaaatca cttgaatggc ataataagtt gtgctataat aatgtagttg ataatgtaaa
    62041 aagaaagtta atataattaa tttttttaaa taaagagaag aggtgactat aatgcaaaag
    62101 gaaatacaac caaaatacaa tccagttgaa gtgcgttgtg cttgtgggaa cacatttgtt
    62161 gctggttcaa ctaaggacga aataaaagtt gaaatatgtt cagagtgcca tccattctat
    62221 acaggaaaac aaaagaacat agaaaaaggt ggaagaatcg acaaattcaa gaaaagattc
    62281 aaaatggact aatttttata aaagtggagt tggaggaagc caactcctat tttattacaa
    62341 aaaaacattc atattctact ttaaattgtc tttttgtatt ataataataa atatgtaaaa
    62401 ttgagtattc taaatacaat aaaatgaggt gagtggatgg caaaacaagc tgtaggtggg
    62461 caagctgtta ttgaaggtgt aatgatgcag tcaaaagaca aaagagcggt agctgttaga
    62521 aaaagtgacg gagaaatagc actaaaagaa gatagaataa aaagttgggt aagagataag
    62581 aatatagata agataccttt tgttagaggt tcttttgtta tgatagatac aatgattcaa
    62641 ggcataaaaa gcttaaactt ttcttcagag ttttttatgg aagaagctga agaggataaa
    62701 tttgatttat ttataaagaa aatttttaaa gataaggcaa atgatataat cataatattt
    62761 tcattggtta tagcaatgtt actttctgct ggattattca tttttatacc tacattggta
    62821 ggaggcgctt tttctaaagt aatgcctaat gattttatgc ttaatttaat agaaggaatc
    62881 ataaggatag ctatattatt tgcatatata gtattgattt cacgaagtaa ggatatagaa
    62941 agagtctttc aatatcatgg agcagaacat aaatctatat attgctatga aaatgattta
    63001 gaacttacag tagagaatgc tagaaaattt aaaagattac atcctagatg tggtacaaat
    63061 ttcttattta tagttatggc tgtatcaata atattgtttg cattttttgg ttggccaaat
    63121 ccaatcctta gaatatttat gagaattata tgtgtgccta tagtagcagg tttatcttat
    63181 gaagtaatta gagttcttgg gaaatatgat aatggattta ctaaaattat tgcatatcca
    63241 ggaatgatgt tgcaatattt tacaacaaaa gagcctgatg atgagcaatt agaggttgct
    63301 ttggaagcat taaaggcagt agtagattaa agaaaaggat atttgttatg acaataaaag
    63361 atataattat taaatattca gatatattaa aagatataag tgatactcca agattggata
    63421 cagagttatt gttacaaaaa acattgggtg ttgataggtt atatattcac ttaaatctaa
    63481 ataaagagct aactgaagag caaaaaacag aatttatagg ttttgcagaa gaaagattaa
    63541 atggaagacc aatagcatat atagttgaaa atagagagtt tatgggatta gatttttttg
    63601 ttaaggaagg cgtattgatt ccaagaccag atacagaaac tttagtagaa gagataattg
    63661 aaatatgtag agaaaaaaaa gatgtaagta tactagatat aggcactggt tctggagcta
    63721 ttacaataag tttagcgaag tacattgaaa attctaaaat catgtctttt gatatatcag
    63781 agatagcctt agaaatagct aaaaaaaatg ctattacaaa tgaagttgat gaaaaaataa
    63841 aatatattaa ttctgattta tttacagcaa taagtaatag taacataaaa ttcgatatca
    63901 tagtttcaaa tccaccatat attaaaaaac aagatataga aactctgcac acacaggtta
    63961 aagattatga gccatataat gctcttgaag gtggagaaga tggattagac ttttatagaa
    64021 gaataacaga acaaggtaag aaatatttaa ataagtttgg aatattagca tatgaagttg
    64081 gtcataatca agctgaagat gtaataaata ttatgaaaag taatggatat aagaaaatat
    64141 atacaaagaa ggatattcaa ggcattgata gagttgttat aggttacaat atatgatata
    64201 atcaacaatt gatatgttac atttaatcga ggtgaaagta tgttaaaaaa attagaggta
    64261 ttggaagata catataaaga cttaagtgaa aaaataggtg atccggatgt aataaatgat
    64321 caaaaagttt ggcaaaaata tataaaagaa catgctgact tagaacctat tgttatgaaa
    64381 tacagagagt ataaaagtgt tttagatagt ataaaagaat caaaagaaat tttacaagaa
    64441 gagtcagatg aggaattaag agaattagct aaaatggagt tagctgagat ggaagaaaaa
    64501 gtagcacctc tggaggaaga aataaaaata ctattattgc ctaaagaccc taatgatgat
    64561 aagaacgtta tagttgaaat tagaggtgga gctggaggag atgaagcagc tctatttgcg
    64621 ggtgatttat ttagaatgta ttcaagatat gctgaaagaa gaagatggaa aatagaatta
    64681 ttgagtgcaa gtgatactgg agttggtgga tataaagaag tatcttttat gataaaaggt
    64741 aaaggtgcat attcaagatt aaagtatgaa tctggagttc atagagttca aagaatacca
    64801 tcaactgaat ctggtggaag aatacacaca tcaacttcta ctgttgcagt attaccagaa
    64861 gttgaagatg tagaggttga aataaatcca aatgatttaa gaatagacgt tttccgttct
    64921 tcaggtaatg gagggcaaag tgtcaatact actgactctg ctgttagggt aacacatata
    64981 cctacaggtg aagtagtatc ttgtcaggat ggaaaatcac aattaaaaaa caaagagcaa
    65041 gctttaaaaa tattaaaagc tagactttat gataaagcat tggcagaaca acacaaagat
    65101 atagcagcag aaagaaaaag ccaagtcgga acaggagaca ggtcagaaag aataagaaca
    65161 tataacttcc ctcaaggtag aataagtgac catagaataa atttaacttt atataagcta
    65221 gatgcattct tagatggaga tatagatgaa atgatagatg ctttaattac tgttgaccaa
    65281 acagagaaaa tgactgcaat ataagtaatg ttttaaagaa gctgtttctt tctagaaatt
    65341 attttctatt ttgaaacagc tattttgcat tttaggtcat gttatcgtat tctactgtat
    65401 ataattgtta tatacaagta taggagggtt atatgatact aaaagtaaca ataattggac
    65461 ttttggcagg tgttataggg acaggattag gaggagtaat atcagctatt tttaaaagag
    65521 aggttgataa atatctaagt ttttttatgg gaatatctgg tggaataatg ttggctgtag
    65581 tggtgtttga tttgatgaaa gaatctatgg acaaaatggg gataatcaat acagttatat
    65641 ttacgtttgt tggagctctc ataactatgt acataaaaac aaaattagat atgtctggaa
    65701 atatggcatc cggatatctt atattcataa gtatattact acataattta ccagagggac
    65761 tagctattgg ttcttctttt atgtcaactg aaagtttagg tattacactt gctatagtta
    65821 taggtttaca taatatacca gaagggttag ctatggcatt aggtttagtc tgtaataaaa
    65881 tgaaactaag taaagttatt ttatttactg taatagctgg attacctatg ggtctaggaa
    65941 gttttttagg tgtttatttt ggaggagtat ttacttctct tataggagta tttcttgcta
    66001 cagcaggagg tactatgatg tatgttgtat tggaagaaat ttttccgcat tcaaaaagtg
    66061 tgtattgtat aattggtttc ttgttaggta caatgattgt aaactatata taaaattaaa
    66121 atgaaagcag gcatacaaaa gatgaaaact ataataagta atattgatat aaataatatt
    66181 gattatgagg aaataaaaat acaagcaaaa cttcttagag aaggtaaaac agttattttt
    66241 ccaactgaga cagtttatgg gctaggtgca aatgcattag atgaaaatgc agtaaagaag
    66301 atttatgaag cgaaaggaag acctagtgac aatccattaa tagtccatat atatgaaaaa
    66361 gaagaagtat atgatttagc caaagatata agtgataaag ctaaacttgt tatagaaaag
    66421 ctttggccag gacctataac aattatatta aataaaaaag atataattcc atacaaaact
    66481 agtggagggc ttgatacagt tgcaataagg atgccttcta atattattgc cagggcaata
    66541 ataaaagaag ctggtatacc tattgcagct ccttctgcaa atatctcagg tcgaccatct
    66601 ccaacaaaag caaaacatgt atatgaagag atgaatggaa gagtagatgg aatagtttta
    66661 ggaggagaca gtaattttgg attggagtca actgtattag atttaacaga agaaactcct
    66721 atgatactga gaccaggaag tataactaaa gaagttttag aggaacttct tggagaagta
    66781 aagcttgacc catcattaag taaaaaagaa gataatcaaa aagctaaagc tcctggaatg
    66841 aaatataaac attattctcc aaatgcagat gtatatatca tatctggaaa aagagaaaat
    66901 gtagcaataa agattaatga tatgataaaa tctaatagag aaaaaggtct aaagacaggt
    66961 gtaatgtgta ctagtaaaaa ccgagagttt tatgatggag aagtaatcga tttaggaaac
    67021 tctcttgaag aagttgcaag taatctgttt gatgctctta tagaaatgga caaaaagagt
    67081 gttgatgtca tatattcaga agagttccct aagactggag ttggacaagc aattatgaat
    67141 agactactta agtcagcagg atacaaagtg ataaaagctt aaaagggagt tgtaaaatat
    67201 gaatatactt attgtgtgta caggtaatac ttgtagaagc cctatggctg aggccatatt
    67261 aaagaaagca attaaagaat cgggaagaag tgttgaagag tattctatat catcagcagg
    67321 tatatctaca gcaaatggaa tgagtgcttc tgaaaattct ataaaagcac taaaggaaat
    67381 cggtatagac ttatcaaatc atagaagtaa agtaattacc aaaaaattaa ttgatgaatc
    67441 agatataata ctaacaatga ctaaatctca taaagaaatt ttattacaag cagttccaaa
    67501 atgcaaagaa aaagtgtata cttttaaagg gtttgcaaat aaaaatgagg aagatatatc
    67561 tgacccattt ggtggaaatt tggatagtta tagaagcact atgagagaaa tagtgtattc
    67621 tgtcaacgaa atagtaaaaa aaatatgaaa cggaggataa ataaatgaag ataggattag
    67681 gctgtgacca tggaggatat aatttaaaaa aagaaataat aagctattta gaaggtaaag
    67741 gtatagaatg tgtagattat ggaactaata atgcgacaga ttctgttgat tatcctgttt
    67801 atggagaagt agttgcaaat tcggttataa ataaagacgt agattatgga atattatgtt
    67861 gtggtacagg aataggaata tctttagctg ctaataaggt tcctgggata agatgtgcag
    67921 ttgtatcaga tgtattttct gcaaaaatgt caaaagcaca taataatgca aatatgttat
    67981 cattaggaga aagagtttta ggaaaaggtc tagcacttga gatagttgaa gcatggatta
    68041 atacagattt tgaaggtgat agacatgcta gaagagtaaa tatgattaaa tcaatagaag
    68101 aaaaacataa caaataataa aaattacagt tttatcagga ggaattatca aaatgagcaa
    68161 agtgatagag acaaaccatc cattaataca acataaatta actttaatga gagataaaaa
    68221 tactggttct aaggatttta gagagctttt aactgaaatt gcaatgttaa tggggtatga
    68281 aataacaaaa gatataccat taaaagatgt agaaatagaa actcctattc aaaaaacatc
    68341 atctaaagta gttgcaggta aaaaattagc aataattcca attttaagag caggtcttgg
    68401 tatggtagat gggttagtaa gtttaatgcc agcagcaaaa gttggacatg taggactata
    68461 tagagaccca gaaacattaa aaccagttga atattactgt aagcttcctc aagacatagg
    68521 agaaagagat ataatagtag ttgaccctat gcttgcaaca ggaggttctg ctgtagcagc
    68581 tatagattta cttaagtcta aaggagctaa aagtataaaa ttagctaact tagtagctgc
    68641 accagaaggt atagcagaag tacaaaaata tcatgatgat gttgatatat atgttgcatc
    68701 agttgacgaa agattaaatg aacatggata tataattcct ggtcttggtg atgctggaga
    68761 tagattgttt ggaactaaat aaaaataaat aactataaat atttattagg gactttctta
    68821 tatagtgtat ataattttat gtaagaaggt tcctttttat atattttctc aaaataggaa
    68881 ttattgaatt gataaatttc tcgaattgag aataaaaagt ttttaccaat taaaaaagat
    68941 tgcttatttt acagggtttt atagaatagt agtctatttt aatgtggcat gttagttgct
    69001 tacgattaag tgtatagata ttaagcgtat tagttaaatt aagtgttgaa tattaataaa
    69061 tattattggg agtggtaata catgaagaat tgtatagtag taagaggagc tggagattta
    69121 gcaacagcag ttattcataa attacacaac agtggtttta aagtagttgc gttagaaata
    69181 gaagaaccat tagctataag aaggcaaatt tctttttgcg aggctgttta tgaaaaaaaa
    69241 gtaactgttg aagatgtgga atgcatattt tgcaatactg aaaaagaaat agaagaagct
    69301 ttatctcaac gtaaagtagc cttgattata gacccaaaag gagaaaaatt atctaagtta
    69361 aatccaatcg ttttggttga tggaatactt gctaagaaaa atttaggtac gactaaagat
    69421 atggcaccac ttacaatagc tttaggtcct gggttttgtg caggcgaaga tgtagatgtt
    69481 gttatagaga caatgagagg tcataatcta ggaagaacaa taactaatgg tagagcagaa
    69541 aaaaatacag gagtaccagg agcaataaaa ggtttttcta aagagagagt aatgcattca
    69601 cagcatgatg gtataatgga aaatgtatgt aagataggtg atatagttga aaagggagac
    69661 ctactttgct atattaataa ttatgaaaaa aaacatgaag ttagagcaac aatatctgga
    69721 gttcttagag gtttattaaa agatggagca agggtcaaca aaaatttaaa aatattagac
    69781 atagacccta gaaaagaaga agttaagaat gcttttacaa tatcagataa agctagatgc
    69841 atagctggag gggttttaga agccatacta aacaatggga tttatcccca aaattaattt
    69901 atactagata aagctattaa tattttatta agatgatata ataaatttaa tagattaaag
    69961 agagcatatg acgggtattt aaaatttaaa tggtaaaaat gctctttttt tattggacat
    70021 tcaattaaca tgtgtatata atataaaaat aagtatttat ttaggttgaa atctaataaa
    70081 tacataatac cagtacataa gtaaagagga gaaaagtaaa ttatgagacc atcatgggac
    70141 gaatacttca tggaaattgc agaagtagtg aaaaagcgtt caacttgtat tagaagacaa
    70201 gtaggagctg ttattgtaag agataaacaa atattaacaa ctggatataa tggttctcca
    70261 agaaatcttg aacactgtga aaatattgga tgtaagaggc aagagttaaa tattccctca
    70321 ggagaaagac atgaattatg cagagcatta catgctgaac aaaatgcgat aatacaagct
    70381 gctcataatg gcattagtgt agatggggca actttgtatg ttactacaag accttgtgtt
    70441 ttgtgtgcaa aaatgtgcat aaatgcaggt atattaaaaa ttgtctatga aggtgattat
    70501 ccagatgata tgtctacaga attattaaaa gaagcaggaa tagaactcat aaaattttag
    70561 tagacaaaaa ttatatgaca ataagtgcca aattgtgaca ctggaataca atggtattaa
    70621 atgattaaaa gaaagtattt gaaaaatcat cagattagta gtaagatata ttttataatt
    70681 aaataaattt atgagataga ttaattacat gttatttatt ttgtaataat gagggatact
    70741 atttatgagt aaaagaaata cacatacaga aattgcaaag ttgtttagtt taataagtca
    70801 aataggattg atgattgtaa tatcaatatt aggatgtact ttcttaggaa aatttttgga
    70861 tagtaaattg aatactactc cagttctgac aataatattt ttattgttgg gtgttggagg
    70921 tgcttttagt ggtgtttata aaactctaat agtatataca cgaaggaagt gatatattgg
    70981 atataaaatt acttaaccag gtaaggtcag taacaaaagg tatagtaata tttgatgtag
    71041 ttttaattgt gttaatgttg ataacatcaa cattaagtaa accagtatta ttaggactta
    71101 tatttggctc tataatagct atgttaaatt ttagattatt agcgatatca ctggaaaagt
    71161 cagtgacatt tcctgctggg aaggcacaag cttatgcatc agcacaatat gctattagat
    71221 tatttataat ggcagttgtt ctatttgcat cagctacggt accacattta aatataatcg
    71281 gaacagcatt gggattattg agcacaaagt ttgtcatatt atcaaaaaac tttataaata
    71341 aattaaagag gaaggaggca taagtatgaa tcaagcgcat tattatctca taggaaactt
    71401 taagattagt gaaacaatac tagtaagttg gggaataatg gcctttttag cgatagcatc
    71461 ttattttttg actagaaact taaaaaaagt tccaactagt aaagttcaaa tattcttaga
    71521 atttgcagta ggtggtcttg ctaaaatggt tacagatgtt atggggaaaa atacagtaaa
    71581 aagaatgcca tatatgatac catacatagg aagcttgttt ttatttttcg catgttcaaa
    71641 tttaagccca ttacttggat taaggtcacc aacaaccgac ttagacacaa ctgctgcatg
    71701 ggcaatgatt acatttttta tgatttattt tgcaggagtt aaatttaagg ggttatcata
    71761 ctttaaagaa ttggctcaac cacttgccat aatgttacca atcaatatta taggtgagtt
    71821 agctagacca atatcattaa gtttccgtcc atttgggaat attttaggtg gaacaataat
    71881 aatgggtctg ttttatcaac ttttaggttt tatatctagt ttgataccag gattatcaat
    71941 accaattgga cagatattaa taccagtccc attacacttg tactttgact tatttgcagg
    72001 attgttacaa gcatatatat tcataatgtt aacaatggta tttatatcaa gtgcaggaga
    72061 gttagattaa gaaatcaact tatattaaga taaaaataaa ataatttaaa aaattaaagt
    72121 tttaaggagg aaataattat ggaaacagca atagtagcgg cagcatcagc aataggagca
    72181 gggatagcag ttgcaacagg tataggtgca ggtataggtc aaggtatagc agcagctaaa
    72241 gctgctgaag cagtaggaaa ccaaccagaa gctaaaggtg atataacatc aactttatta
    72301 ctaggagttg ctatagcaga gtcttcagca atatatggtt tggttatatc aataatactt
    72361 ctattcgtaa atccattctt taaatactta ggaatgtaga tttagtcctt aaatattttg
    72421 agataggttt ataggtaaat catctcaaac ttataatcat gagatgaact ttatcatctc
    72481 gtgattataa gtagttatga tttatggaaa ggaggataat tatggagaaa gcactagtag
    72541 gtataacgtg ggaatttgta ttccaaattg ttaatacttt tataatattt ttacttctga
    72601 gaaagctttt attcaagcca gtattaaata taattgaatc aagagaaaat gatattaaaa
    72661 atgatttggc agaaggcgaa aaagcaaaaa atgaaggttt agctctgaaa aaagaatatg
    72721 agtcaaaaat aaattttgcc aaagatgaag gtcaagaaat cataaaacaa gcaactataa
    72781 gagcagagca gaaatcagat gatatagtaa atactgcaaa gaaagatgct cttgatataa
    72841 aagaaaaagc aaacaaagat atagaacaag aaaaacaaaa ggttataaat gaaatcaaaa
    72901 atgatatatc taacatagca ctacttgcag catctaaagt tattgaaaaa gatttagata
    72961 aatctaaaca tgaagaattg atagaaaact ttataaaaga ggtaggggaa gctaaatgat
    73021 aaatgtaata gcaaatagat atgccgaagc cctatttcaa ttaggagaag aagaaaattc
    73081 aactgatgtt ttattcaaag aattagaaaa agtagtagat atgatgacta aagttagtaa
    73141 agatttctac aaagttttaa aatcaccatt agtttcaaaa tcagaaaaga aaaacttggt
    73201 agaaattatt tttagtaaag aagtaagttc taacataaaa aactttttaa aagttttagt
    73261 agataaagac agaatatcat atttagaaga tatcgaatta gcttataaag aattattaaa
    73321 taagaaaaat aatgtaattg ctggtgtagc aataagtgct attccaatga gtgaaacaga
    73381 tattaaagaa cttgaagtca aactttcaaa taaatacaac aaaaatgtta ctatagaaaa
    73441 tgttgttgac aagactatac tagggggagt tctagttaga attggaaatg aacaaataga
    73501 tggcactgtg aaaactcgtc ttgataagat gaaagaaaag ctatctgaag taatatctta
    73561 agaatggcgg tgaacccatg aacttaaaac ctgaagaaat aagttctata attaaacagc
    73621 aaataaaaaa ttatgagaat aaagttgagt tgacagatac aggtagtgtt ttaacagttg
    73681 gggatggtat agcgagtgta tatggattag aaaaagctat gtctggtgag ttgctagagt
    73741 tcccaggtga aatatatggt atggcactta acttggaaga agaagtagtt ggagctgtta
    73801 tccttggaga tgacagtgaa ataaaagaag gcgatatagt taagagaact ggaagaatag
    73861 ttgaagttcc agttggagaa gctttaatag gtagagttgt aaactcttta ggtcagccaa
    73921 tagatggaaa aggacctata gcgtacacaa aaactagacc agttgaatct gaggcacctg
    73981 gtataataga tagaaggtct gtttatgaac cattacaaac aggaatcaaa tcaatagatt
    74041 caatgatacc aattggtaga ggtcaaagag aattaataat aggtgacaga caaactggta
    74101 aaacatctat agttattgac actatactaa atcaaaaagg aaaagatgtt atctgtatat
    74161 atgtagcaat tgggcaaaaa cgttctacta tagctcaatt agttagttct ttagaaaaag
    74221 gtggggctct agattataca atagtagttt cagcaacagc atctgaatca gcaccacttc
    74281 aatatatagc accatatgct ggagcagcta tgggtgaaga atttatgtac aatggaaaac
    74341 atgtacttat agtatatgat gatttaagta aacaagccgt tgcatataga gaaatgtcat
    74401 tgttacttag aagaccacca ggacgtgagg catatcctgg agatgtattc tatttacatt
    74461 caagattact tgaaagagca gctaagttat ctgatgaatt gggtggaggt tcaatgactg
    74521 ccttgcctat aatagagact caagctggtg acgtttctgc atatatacca acaaatgtta
    74581 tatctataac agatggtcaa atatacttac aaccagagtt attctattca ggtgtaagac
    74641 cagcagttga ccctggtata tcagtatcaa gggttggtgg ttctgcgcaa attaaagcaa
    74701 tgaaaaaagt tgcaggaaca ttaaaacttg catattcaca atatagagaa cttgcagcat
    74761 tctcacaatt tggttctgac ttagatgaag atactaaaaa gagacttgct caaggtgaaa
    74821 gaatcgttga aatattaaaa caaggtgagc atcaaccaat aaaagttgaa aatcaagtta
    74881 tgataatata tgctgttata aataatcatc tagaggatat tccgatagat aatatagcta
    74941 gatttgaatc agaattgtat gcatttgtag ataataatta tccagaaata tcaagaaaaa
    75001 tattaggtgg agaagacttc actcatgatt taacagatgc aataaatgaa tttaaagaaa
    75061 agtttgttgt tgaagtataa tcctttttaa aaaaggaggt aaattaattg gcaggagctg
    75121 gaatcaaagc aatcaaaaca cgtatgggaa ctgttgaaag tacaaagcaa ataactaaag
    75181 cgatggaact agttgcatct tctaagctta gaaaagcaaa agaaaaagct gaagattcaa
    75241 gagaatattt taatacttta tacaatacag taaaagatat tgcccaaaca acacgtggaa
    75301 ttagaaatga atttttaaaa gaaagagaag taaaaaataa gtgctatgta gtagtagctg
    75361 gagacagagg acttgcaggt gggtacaatt ccaatgtatt aaaggagtct gtctctcata
    75421 tgaaaggcaa aaaggaaaca gttattactg ttggaaagaa agcgcatgaa tttttttcta
    75481 aaagaaacta caatatagtg aaagatataa atagtgttga agcttgtgga tatgaagatg
    75541 cgacagaaat ttcacaaact attattgacc tgtataaaaa aggtgaagta gatgaagttt
    75601 atattgctta tacaaaattt aaatctgctt tatcacaaga agttgaaatt ttaaaattgc
    75661 ttccattagt ctttgaaaaa gatacagacg aacaaggaat ggaagtaaaa gaagagaaac
    75721 aaaatagatc aaaagtacaa tatataccat cagcagaagc agttttaagt tatattgtac
    75781 ctcagtttat atcaggtaca gtatatggtg gaattttgga atcttttgca tcagagcaag
    75841 gtgctagaag aactgcgatg gaatcagcca cagacaatgc gaatgaaatg ctatctaatt
    75901 tagagttaag ttataacaga gcaagacagt cagctgtaac tcaagaaata acagagatag
    75961 ttggtggagt tgaagctcta aaatagggag gttaggaaat ggcaaatgta ggtaaagtag
    76021 tacagattgt aggagctgta ctagatgtta agtttgatag tgaacaaagc ctacctaact
    76081 tattaaatgc gttagtaata aagttaggag ataaagaaat agttgcagaa gttgctcaac
    76141 atataggtga tgatactgta agatgtatag ctatgagtgc aacagatgga cttgtaagag
    76201 gtatggaagt tgtagataca ggaggaccaa taagtgttcc tgttggagat gagactttag
    76261 gtagaatatt caatgttctt ggaaaaccag ttgatgggaa accagctcca aaatctgcac
    76321 ctaaattacc tatacataga ccagcaccgg cgtatgatga actagaaact acagcagaga
    76381 tactagaaac tggtattaag gtagttgact tactagctcc atatctaaaa ggtggaaaaa
    76441 taggtctatt tggaggagca ggagtaggaa agacagtttt aatacaagag cttataaaca
    76501 atattgctaa gcaacatggt ggtatttctg tattttcagg agtaggagaa agaacaagag
    76561 aaggtaacga cctttatggc gaaatgagtg agtctggagt tataaataaa acagctctag
    76621 tatttggcca aatgaatgaa ccacctggag cgagaatgag agttgcttta actggactta
    76681 caatggcaga acattttaga gatgagcaag gacaagacgt tttacttttc gttgataata
    76741 tattccgttt cacacaagct ggttcagaag tttcagcact tctaggacgt atgccatcag
    76801 ctgttggtta tcaaccaaca ttagctactg aaatgggtgc gcttcaagag agaataacat
    76861 caactaagaa aggttcaata acatctgttc aagcagtata tgtaccagca gatgacttaa
    76921 ctgacccagc accagctaca acattctctc acttagatgc aaaaacagtt ttatcaagac
    76981 aaatatcatc actgggtata tatccagcag ttgaccctct tgaatctaca tcaaggattc
    77041 ttgaccctag tatagtagga aaagaacatt atgaagtagc tagaggtgta caatcaatac
    77101 ttcaaagata taaagaactt caagatataa ttgctatact tggtatggat gaactatctg
    77161 atgaagataa gttaatagtt gcacgtgcta gaaagataca aagattctta tcgcaatcat
    77221 ttacagttgc tgagcaattt acaggaaatc caggtcaata tgttcctgtt aaagagactg
    77281 taagaggatt taaagaaatt cttgaaggga aacatgatga cttaccagag tcagcattct
    77341 tatttgtagg gacaatagaa gacgctgtta aaaaagcgaa gggaagtatg tagtcatggc
    77401 cagtgaattt tcattgaaag ttgtaactcc aaataatact ttttatgatg gagacgttga
    77461 aatgatagta gttagaacta caaaaggaga caaaggggta ttgaaaggtc atataccatt
    77521 tgtttcaggt atacctgtag gaactttaaa gataaaaaaa gagggaagtt ttaaagaggc
    77581 gaaaatagca gaaggatttg ttaatgtaac tcaagataaa actgtcatat tgacagaatc
    77641 tgctgagtgg atttagtaat ttaatttaaa atataaaaag tcattttgac caaaaaactt
    77701 ttgggtaaaa tggctttttt atattttact gttaatagaa taacgataaa attgtaatct
    77761 tttagtgata ataaattcac aaaatgttta aatttactgc aaaattatgt tgtaattaat
    77821 ataataaaga agatttagat agcttttatg taagtgaaaa agtcttcata taagaaatac
    77881 atataaaatt tttataaaat ttaaaaaatt tgcttagttg tgtagtataa taaataatat
    77941 aatagatttg tatgtaatat tcattacaaa taattttaaa agttacagtt ttattataat
    78001 gattattaaa ttaagataag taacataaac taaataataa tatgtattat cgatagtaaa
    78061 ttcattatta attattgaaa gaagtattgt aaattttctg gaggaacaat gaatatattt
    78121 gatattggcg tagacataat tgaaattgac agaataagaa aagctataga aaagaataat
    78181 aggtttttgg agaagatatt tacagataga gaaatagagt attttaattc taagaatttt
    78241 aaagcagaaa gcatagcagg taatttcgca gctaaggaag ctataagtaa atctataggt
    78301 acaggaatta gagtgtttaa ctttaaagat atagaagttc tcagaaatga aatgggaaaa
    78361 ccaatagtaa aaacttataa taatctagca aaaatgtgca tagattataa tgttttagaa
    78421 ataaaagttt caatatcaca ttcaaaagat tatgctatag caaatgcgat aaccataatt
    78481 aaggactaag gagtgattac attatgatgg ataaaacagc aaaagaaata atgacaacag
    78541 atgtaatagt agcaaaacaa gatgatagta tagcagatgt agctaatatg ctaattgcag
    78601 aaaaaatagg aggtctgcca gttgtagatt cagagaatag agttgttgga ataatttctg
    78661 aaacagatat tcttaaaaaa gaaaaatata tagaagcacc tctctatata aatctattac
    78721 aaggattgat tttcttagat gacttaaaaa aagtagaaaa agatataaaa caagtagctg
    78781 cttataaggt tggagaactt atgtctaaag atataataaa ggttcatgaa gatgataagt
    78841 ttgatgatgt agctaatgta atgattaaaa aatcaataaa cagagttcct gtagtagatg
    78901 atgacaataa acttaaaggt ataatttgta gatatgatat aataaaagct ttatacaatg
    78961 aataaactga agtaggaggt gtgatgtgag aaaaaagtgg accatagtat gtattatgtt
    79021 cttggcactg gttataattg taataggatg ccaaaaacga cagtccacaa aagaagaagt
    79081 atacaaagat tttcaaaagc agatttctga tatgaattat tacagttgta aagctgaagt
    79141 agaagtagtt ggaaataaaa gcccacataa ttatgtttta attcatactt ataaaaaaac
    79201 tgataactat aaattagagg taatttcccc aaagcattta aaagggaaaa gtatagaata
    79261 tcaaggtgat aaaatattag ttaaaaatcc aaagattagt gatatagtcg agttgcctaa
    79321 tacaggaaaa aataatcaat atctttttat aggagacttt ataaaaaact atcttcaaaa
    79381 cgaggagatg aaagtaaagt tatccaaagg acatttggtt ttagagactt ttattcctgg
    79441 ggataataaa tattttaaca agcaagtatt atatgtaaat gctgacacaa aaaatcctga
    79501 aaaaatggaa gtgttagata aagagggagt gccaagattt acagtaaaat acaaagattt
    79561 tgaatacaga aactaagggg gactaaagac atgcaaaaaa taacagtgcc tacatgggca
    79621 gagataaatc tagataactt aagatttaac ttaaataata ttaaaaattt attagaagaa
    79681 gatattaagg tttgtggagt aataaaagct gatgcatatg gacatggtgc agtagaagtt
    79741 gcaaaattgc tagaaaaaga aaaagtagat tacctagcag tagcaagaac tgctgaagga
    79801 attgaactta gacaaaatgg cataacactt cctattttga acttgggata tactccagac
    79861 gaagctttcg aagattctat aaaaaataaa ataactatga cagtttattc tttagaaaca
    79921 gcacaaaaga taaatgaaat tgcaaaatct ttaggagaaa aagcctgtgt tcatgttaag
    79981 atagactcag ggatgactag aataggtttc caacctaatg aggagtcagt acaggaaata
    80041 atagaattaa ataaattaga atatatagat ttagaaggta tgtttactca ttttgctaca
    80101 gctgatgaag taagtaaaga gtacacttat aaacaagcta ataattataa atttatgtct
    80161 gataaattag atgaggctgg tgtaaaaata gctataaaac atgtatcaaa cagtgcagct
    80221 attatggatt gccctgattt aagattaaat atggtaagag caggaataat attgtatggt
    80281 cattatccat ctgatgatgt atttaaagat agattagaat taagaccagc tatgaaatta
    80341 aaatcaaaaa tcggacatat aaaacaagtt gaaccaggtg taggaataag ttatggacta
    80401 aaatacacaa ctactggtaa agaaacaata gttacaattc caataggata cgcagatgga
    80461 tttactagaa tccaaaaaaa tccaaaggtt cttattaagg gagaagtgtt tgatgtagtt
    80521 ggtagaatat gtatggatca aataatggtt agaattgaca aagatataga cataaaagtt
    80581 ggagatgagg ttatactatt tggagaaggc gaagttacag ctgagcgtat agctaaagac
    80641 ttaggaacta taaactatga agtgttatgt atgatatcaa gaagagttga ccgtgtttat
    80701 atggaaaata atgagcttgt acaaataaac agttatttgc taaaataaaa ccatgatatt
    80761 ataatctggg aggcgatttt gtgtacgata agagtaaaga aaaaatagaa gttactttac
    80821 cagactctct gatttctgaa gttgatagta tagttcagat ggagaacagt aacagagaag
    80881 attttgcaaa agctgctttt cagttctata taactcagaa aaagaaaatt catattaaag
    80941 aatctatgaa aacgggttat agagaaatgg gtcaaattaa tctgtcacta gctgaattag
    81001 gtatgacagt tgaagaagta tcttctgatg ataaaaatga agggaagatt gcccaaggtg
    81061 agtactaatt gtgaaataaa gcgtggtgat ttatactacg ctgatttaag tccagttgtt
    81121 ggttcagagc agggaggcgt tagacctgtt ctgataatac aaaatgatgt aggtaataaa
    81181 tatagtccta cagttatagt atcagctata acatctcaga ttaataaagc caaattacct
    81241 actcatgtag agataagttc caatgaatat gggcttaata aagactcagt aattctttta
    81301 gagcaaatta gaactattga taaaaagaga ctgagggaaa aaattggttg tctagatgaa
    81361 aatatgatga taaaagtaga tgatggactt caaataagtt tgggattgtt tactttttaa
    81421 agagggattt gtcttttatt agacaatccc ttttttcttt taaatatctc ttagtgttta
    81481 attttaatgt actatgttaa taaaattaaa aataacgcaa aaaaatagca taaaagtgat
    81541 ataataatat ggaattgata taaaattacg aactcaaggg aggtaattgc atgagagacc
    81601 ataaaggatt aaatgagatt gcgcgtatca taagaagaga tatagtttca atgatacata
    81661 gagccaaatc tggacatcca ggagggtcat tatcagtagt tgaaatactt actgcgttat
    81721 actttgatga aatgaatgtg gattcttcaa atcctaaaat ggaggataga gatagatttg
    81781 tattatcaaa aggacatgct gcaccagcat tatatgctac attggctgaa aaaggctatt
    81841 ttgataagga agaactgaat ggattaagga agataggaag gatgttacaa ggtcatccag
    81901 acatgaaagg cacgccaggt gtggaaatat ctactggttc tttaggtcaa ggcttttcag
    81961 ttgcatgtgg tatggctatg gcatcaaagt tggataatgc tccatggaat gtgtacactt
    82021 tgcttggtga tggtgaggtt caagaaggaa ttgtttggga agctgctatg agtgctgcac
    82081 attataaact tgataattta attgcttttt tagataacaa tggacttcaa atagatggag
    82141 atatagaaag tgtaatgagt ttaggttcaa tagttgataa atttaaagct tttggttgga
    82201 atgtaattga gatagatgga catgattttg accaaatatt tgctgctctt gacatagcta
    82261 aatcaacagt taaaaaacct acaatgatag ttgcaaaaac tataaaaggc aaaggaatat
    82321 cttttatgga aaatcaagca ggatggcatg ggacagctcc aagtgatgag gagctagaaa
    82381 aagccttgct tgaattagga ggtgctgaca atgagtaaaa tggcgacgag agaagcatat
    82441 ggtaaagcat tagtaaaatt aggtcaaata aatgacaatg ttgtagtgtt agatgcagat
    82501 ttatcaaaat ctacaaaaac acatgatttt tacaaggcat ttccagacag attttttaat
    82561 atgggtatag ctgaacaaaa tttaataggt gctgcttgtg gattatcaac tgctggtaaa
    82621 ataccttttg caagtacttt tgctatgttt gctacaggaa gagcctttga gattataaga
    82681 aattcagttt gttatccaaa gctaaatgta aaaatatgtg ctactcatgc aggtcttact
    82741 gttggagagg atggagcatc tcatgaaagt gtagaagata ttgctataat gagagctata
    82801 ccaaatatga cagttcttgt tccagcggat ggagttgaaa cagaaaaaat tatttttgaa
    82861 atagctaagt ataatggtcc tgtttatgtt aggttaggaa gaagttcagt accagtttta
    82921 tttgatgaag attataaatt tgaaatagga aaaggtacag tcttaagaga aggaaaggat
    82981 gtatcaatta tagcttgtgg aattatggta aatgaagctc tattagcaca agaaaagttg
    83041 caagaagaag gtataagtgc tagagttata aacatgtcct cgataaaacc tatagacaaa
    83101 gatttaatat tagaatcagc aaaagaaacg aatgttattg taacagtaga agaacatagc
    83161 ataattggag gattaggttc tgctgtaagt gaggtagtgg gagagtcttg tccaaccatt
    83221 gtaaagaaag ttggaattaa agatacattt ggagaatctg gtactccaaa tgaattgtta
    83281 aaaaaatatg aattaacttg tgatgacata gtaaagactg ttaaagaagc tattattgca
    83341 aaaagaatgt aagagatata aattattcat gtttgttaat aatataatat atttaaaaga
    83401 gagttataaa gtgctatatt aatttatatc tctctttttt ttatatgata tcaatgtatc
    83461 aaaaatgtaa taaaatattc aaatttttac aaaaatagag aaaatattca aatatatatt
    83521 gactattcag aaaaatatga ctaatatata atttatagag aaattaattt tatatataat
    83581 gactacttag ataaaagaat ctaaaaaatt atgaaaggag gactagggta taaaattaga
    83641 ttgtaagttt taagttatta tactaaaaag ctataaaaca gttatcatgt attttatgtt
    83701 aaaggaaatt gtaggtagtt tatcgaattg tttaagcaga agaaaaaatt tcacatgggg
    83761 aggtaactga gatatgtcag aaaaagtaaa tgttaaaaca gtcatcagtt tcgcaggtgc
    83821 gtatgtagca acagtaatcg gttctggatt tgcaacagga caggaaataa tgcaattctt
    83881 ctctttttat ggttttgcag gtattattgg tgggataatt tcaatggtat tattctcatg
    83941 gatgggtgct tcagttatgt caaaaggtaa agagcttcaa cttaaagaac ctatcaaaat
    84001 ttatcgtgtt tattgtggta agtatttagg aatattcttt gaatggtttg gacctttatt
    84061 cttatttggt gttttcgtag taatgatttc aggagcagga gcaactttaa ctgaatacta
    84121 tggattaaat ccatttgtag gtagagtagg tatggcagta gtagcattat taactgtttc
    84181 attaggtctt gatagattat caaagatact aggtggaata gggcctataa taataatctt
    84241 tacactttta gttggtggta taagtttagc taaaaacata ggtaatatag gagaagctgc
    84301 acaagttctt agcactgtaa agatagctaa accagttcca aatgcttatc tatctggtgt
    84361 aatatatact acttataaca caattgttgt tatggcattc ttaactggat taggagcaag
    84421 tgctgctaac aaaaaagaag ctatttgtgg tggtatatta ggtggagtag cacttatggc
    84481 tgcagctata atgatgcact tagctattct ttctgatata ggaaacttat attcaaaagc
    84541 aataccatca ttattcttag cagataagat ttcaccaata attggagttt tattctcaat
    84601 aattcttata ttaggtatat atacaacagc tgtaccttta ttatggtcag taactaatag
    84661 atttgtagat gataatcatc ctaagtttaa attaataact ttaatagcag ctatattagg
    84721 tcttataggt ggattcctac catttgataa gctggttggt attttgtatc catatactgg
    84781 atatatgggc gtcataatac tggtttgtgt tctttataga cagattacaa aaacatctgg
    84841 atatcaagaa ggaatcagtg acaaataaat attttttaat attgtaaacc caagagctat
    84901 atgaaaacaa taaaaatgtt ttcatatagc tctttttatt ttttagctcg tttattatga
    84961 aataggaaaa acatgttttt tagttacatt acatatattt ataattatgg ataaatatat
    85021 actaatcaat aatttagagt ctaagataag tttataaatc atatatttag aatatatggg
    85081 aggagtgata agattggatg taaagtttaa tattaaaggt ataatttatg gagttatagc
    85141 tcttgtattc gttatagggg gatttatatt cataccaagt atgtttgtag agaaatctaa
    85201 acccatagat tatacagtat tacaaagaaa ttcaatacca gaaaagatac tagatgtgat
    85261 ggataagtat acaaatgaag aaagagcatt agcggctaaa atcgataata aaatatacat
    85321 tatagtgact agaggaaata ataaatatgg tatagaaatg gacaaaatag aaagcgtggt
    85381 tgaggaagga aaggatgttt tgagagtcaa gataaagtat aaagacaagg aagattcttt
    85441 tccatacata gttgttgaaa caaatatgag tgaacttcca gatagaatag aattaaatgc
    85501 gacgaaataa gaaggtattt tataattaaa taactgcata ttgtacaaca aagtcatggt
    85561 ttttattaat gtaagtaaat tgtgtatggt tcttattgtt gtaaaagcca tgacttaaaa
    85621 tgcttataaa gtaagatatt aacagtagaa tttattacta tattaaataa ggtctggaag
    85681 tacttaatgt tctaattatt tggagtgata attctagttt cagtaactat gtagtctaat
    85741 tgtgcatcat gagtttcttt tggaatagaa ttgaatatct ggaagtcaaa tgctatgcct
    85801 atagttatag catcttttct taagttttct aaaaatctat cataaaatcc tccaccatat
    85861 cctaatctat agcaatgtat atcatatgct acagctggta caattacaac atccaaggct
    85921 ttaatatcaa ttttaggtga tttttcgtta ggttctctta ttccatatgc tccgattctc
    85981 aatccatctt ttaaatctgt tatttgagta gggattaatg tacgattttc ttttattgtg
    86041 ataggacttg atactatttt ctttagagac aaaagttttt tgattaaatt atctgtttga
    86101 acctcattgt taaaatctag ataaagcatt atattagttg catttcttat gtcttccatt
    86161 tgaagtaatt tttcagttat taaatttgaa ttactaagta cgaaatttgc atttttattt
    86221 tttcttgatt caataacttt ttttctaaat tcttttttca taaaataatt cctcccttaa
    86281 tgtgttataa tgtgtacagc aattgtattt aatataaatt ttagtataat ttattgtaat
    86341 aaagcaatat atttgggtaa atgtaataaa aataacagct agtcatataa taataatagt
    86401 ttatgtaaaa ggagatgtat cttgtgattt caaagaagaa agctattttt ttaggggtga
    86461 ttttaataat tataacagct atggttacat cagcatttca gttgacattg gggaataaag
    86521 ttgtaatatc gaaagaactc tatgaagact ataaaaaata tgataagttg ttaggactag
    86581 aatctattat aaaacaagat ttttataaaa aagtatcaga tactgatttg gtaaatggag
    86641 catcaaaagg tctatttcta ggaacaaatg ataagtattc tggttattat actaaagatg
    86701 aaatggaaaa tctaattaat gatagtgaag gttcttatgt tggtgtaggt atgtatatag
    86761 gggcatcaaa agatggtggc ttagtagtag ttcctatgaa agattctcca gcagaaaaag
    86821 caggtgtaaa atcaggagat aaattagtaa aagtcaatgg aaaatctgtc tcatataaaa
    86881 attcagatga agctgttcgt atgatgaagg gtaaaaaggg gaaaacagtt gagctgacta
    86941 tattaagaga agataaacaa ttgaacttta aagtaaaaac agaccaaata gttgagaaga
    87001 gtatagagag taaagtaatt gataatgatt taggatatat agaaattacc caatttatat
    87061 caagtacata tactgacttt gataaagctt taaaagaatt aaaagcaaaa aatatcaagg
    87121 gattagtaat agaccttaga aacaatcctg gtggaatgct agatatatgt aaagaagttg
    87181 ctgatgagtt aattggtgaa ggaactatag tatatacaaa agataataag ggaaatactg
    87241 agtatttgaa atctgataaa gaaaaattgg gacttccaat agtagtattg actaatggag
    87301 aaagtgcctc tgctgctgaa atattaacag gtgcaatcgt tgacaataaa gaaggtattt
    87361 ctgtaggtac tacaactttt ggtaaagggt tggtacaatc agttgtaaga ctgaaggatg
    87421 gaacaggtta caaactgact actgcccaat attttacacc taatggagat tatatcaatg
    87481 aaaaaggtat aaagcctaca attgaagaaa aagatgaaaa taagcaatta gatgtagcaa
    87541 ctaagtggct tagagaacag attgataaat aggatttaat tcttataaac ttatattata
    87601 aaataaagag tcttataaaa ggagtgtctc aaaatgaaat ttttagttca tgaggcactt
    87661 ttttgtaaga tgtcgaatgt attttcatca ctttaacaat gaaaaagagg cttatctcta
    87721 tttttggaca gcctccataa ctttatattt aacctattta ttaactttgt acttacatat
    87781 accatttata taagtttcgt gtatattaaa gcccttatct gttactataa agtctgcatc
    87841 cataccttga tatatggagc cacagacatt atcaatatta caacttaaag caggtacata
    87901 tgtagccatt tttattgcat cttctaaagt cgatatattc caatcaacca tatttctcac
    87961 agccctgtcc atagttaata cactaccagc taaactccca ctacttaatc ttgcaacact
    88021 attttttaca tttacattaa acttaccaag agtgtatttt ccatcctcca tagcaccagc
    88081 cctcatacaa tctgtaatta aagctatgtt attactagac ttagcatcca tcattatttt
    88141 aatagctatg gggcttacat gatgaccatc acaaattaat tcagcataag tatcttttag
    88201 taccatagca gctccaacca ttccaggttc tctatgattt aaagggctca tcccattata
    88261 tgtatgtaca aacactttag cacctgaatt aacaacttgt ttaacttgtt caaatgtagc
    88321 tgaactatga ccaagagaaa ctgagatatt atttttagtt gcatattttg ttaattctat
    88381 tgaaccttta cgttctggag caattgctat ttttcttatt aaatttttcg attttttttg
    88441 ccataatttt aatatattga tgtcagggtc ttgaaaatat ttttcatttt gagcaccctt
    88501 atatttttct gtaaaaaatg gaccttctaa ataaatccct tgtatttttg ccccctcaac
    88561 tttattgaaa ctattgctta tattttctac agaatcactt agtgtatcta cggaatcagt
    88621 taaagtcgta ggtaggaaag atgttactcc atattttaat aagccttttg aaatcgtgtt
    88681 tattgcttca aatgtattgt ccatgacatc tgcacctaaa agaccgtgaa tgtgagtatc
    88741 aactaagcca ggagcaatat atttacctga aaaatctata acattatcag tagtactagg
    88801 tctttcttgc tgaaattcac cgaatttgcc attaattata ctaaggtaac ctttttcttt
    88861 ggttccatgt ttcataaaaa atttatctgc ataaataaaa cttttcaaaa ctgcctcctt
    88921 ataattatgt tattattgtg ttattgacgt ttataatatc attaagtttt attgaaattt
    88981 atttaattta ctatcttaca tgccttactc tatatacaaa tttatcgctt ctagcaacac
    89041 tcaaagtaaa ttcaatgact atattatcat cattgtatgt tgtacgaagt aattttagac
    89101 aaggtgaatc tcctggtact tctaatagcg ttgcttcctt gtcagatatt attccagctg
    89161 aaaattcttc atcagcaact ttaataacct caccataatc ttctctaaat atttcatata
    89221 aaggtttttg ttcgattttt tcttttgtca atcctataaa ttctttcata ggtagatatg
    89281 ttctttcaag catcatagga aggtcattag caagtcttaa acgcattatt tttattattt
    89341 tttcaccagg agttatacct aatttttcag aaaaatactt tgtactttct actacctcaa
    89401 atgataatac ttttgtactt ggcttttttc cttgtgttct catataatct gtaaagctat
    89461 aactttccat taagttttga gaattttgac tgagtgcagc aacaaaagtt ccttttccat
    89521 gtcttttata tatatatccc atatgttcta actcagccat agctagtcta actgtagttc
    89581 tacttactcc atattcatca caaatttttc tttccgaaag cattctatcg tttggttcca
    89641 tctcattttc aatcttagtt cttaatattt caacaagctg gtcatatatt ggtcttttat
    89701 catttctttt tatcataaaa atatagtcct ttctaagtgg ttattaccac aatttgatta
    89761 tagaatatag aattatttat gtcaatgaat aaagtttaat caaaactcaa taagtaagtc
    89821 tattaattta ttataaaatt atggtacatt gacaaaacaa gtaaaataat ttatattcaa
    89881 attggtaata accactttgg gtatattgta gacgaggtat tttttatttt acatattaat
    89941 ttattgttta gaaaagtaaa aaattaataa tgaggagaat ctagtatgat tacagtaata
    90001 acatttaacc catctataga tagaatgtat agggtaaata atataaacat aggtgaggtg
    90061 caaagggtag taagtaagaa tgcaactgct ggaggtaaag gattaaacgt agctaaggta
    90121 tgtaaaattt taaaagaaaa tcctttagcg ataggatttc taggtggatt taatggagaa
    90181 tttataaaaa atgaacttaa aaaattagag atacaaaata agtttacaaa aatagagcag
    90241 gaaactagaa attgcttaaa tataattgag gacaataaag ttagtacaga atttttagaa
    90301 aaaggaccga tagtagaaaa aagcgattta gagagatttg aaaatgatat agaggaagta
    90361 ttaaaaaata ctaaaatact agtggcatct ggtagctatt gtgagaatat gccgatagac
    90421 tattatgaaa agataggcaa tatatgtaga gcaaataata taaaatttat attagataca
    90481 tcaggagaag cattaaaaat agctttaaaa tcaaagccgt atttaataaa gccaaatata
    90541 gatgaaataa gacatttatt aggaataaat atagaatcaa gagatgaaat tatcttatca
    90601 ggaaaaaaac ttattgaaat gggtgcagag aatgtatgta tatccttagg aaaagatggt
    90661 atggtgtatt taaataaaga tagtgtatat gatgtaaaag taccagttgt aaagtgtata
    90721 aatactgtag gtagtggaga tagcacagtg gctggattta gtgtaggtat tctaaggggt
    90781 tataaaatag aaaatttact taaatttgca aatgcttgtg gtataagtaa tgctttaaat
    90841 atggaaactg gatttgtaga tttgagagaa attgataaat atcaagattt agttgaagta
    90901 aaaaagttaa gttaagtata tttaatgtga atatactaag tttaatgttg ttgtaataga
    90961 tttaaaattt aatataaaag atatagtctt atataaaaat aggttagaga aattcatctt
    91021 taacctattt ttataataaa tatctatttt actgaattta taattttttc tagtaatctt
    91081 tgagccttga cacactcttc tccactaata gctggtttta tattattttc tatacaatca
    91141 ataaaatgat ttgatatatc ttcaaaaccc ttttgtttta atatatttac ccatgcacca
    91201 ctttgtttta aaattaggtt tccaccttct tctatttcta gtacattaag attcttaatt
    91261 ctttgaatcc tgccttttga aagaatttca acttgttcta actttgttcc agaatctcta
    91321 tgcatagagg tgtttataga gaaatgttta cctttaagtt tatgacttac aaatataaga
    91381 ttcttattgt ctgttaaaaa taaatcttct ccactaattt caacatcttc atttgctaac
    91441 cataaagcag tgtcaataac atgtatataa tcatctataa gggtactgtc gaatctaaca
    91501 tttcttaagg aatttaatcc atgtttacat atattgatag atacgatttc tgtagcatta
    91561 tttttaattt ctttgtacat aggacagaat ctacggttga atccaaccat taaatttaag
    91621 ttttttttcg tacttaattc gataagttct tctccttgat ttactgttga agcaagaggt
    91681 ttgtctacat atacatgaac acctaaattt aataatattt ttataatttc gtagtgtgtt
    91741 tctgtagagc tatgtagaaa aatgcaatca cattttttag ctaaagactc aatagaatcg
    91801 aatggcatga ttctataatc actacagatt ttttctcttt taactttatt tggagtaaaa
    91861 gctcctacaa actcaaatct ctcagattta gttaatatag gtaaatatgc cttttgagct
    91921 atggagccaa gacctatcat tcccattttt atatttttca taatactttc tcctaaggtt
    91981 tttatattta cagaattgat tataattcag acacgtaaat ttgtaaactt tgtatcaaaa
    92041 aataaactta aggcttatat aagtaaatta gcaaaataag aaatatta
//
LOCUS       DBGJFK010000008        86385 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.008, whole genome shotgun sequence.
ACCESSION   DBGJFK010000008 DBGJFK010000000
VERSION     DBGJFK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 86385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86385
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.008"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(247..2361)
                     /locus_tag="ACOIAP_000702"
     CDS             complement(247..2361)
                     /locus_tag="ACOIAP_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGZ2637615.1"
                     /translation="MFEDKQVINCDTIASNSKHNMYEHDTELLTFFPDEIAHLIDINN
                     KLDDAFKKAENLVDKLDKDYMDTKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKIDKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKAHTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLLELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     AERVRFKSTFDFVKLIDYYIKQMPNKIFIPKDYNFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKLKSILKSLNGMLTIKNTLTLYKDFFKQMNLSN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGGFGQLVNPNHTHTLDDMRQLYNEGELVTLNKSYRSTFEIINFAKKVQDVSS
                     LEPIERHGEEPALVKCTNKQDEVSKIKIEIEEFKKSDNATLGIILKTDSDAEVIYNAL
                     KQEYSVNLISSESSSFTKGVSITSIKMSKGLEFDEVIIPSVNSKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(2608..3468)
                     /locus_tag="ACOIAP_000703"
     CDS             complement(2608..3468)
                     /locus_tag="ACOIAP_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637616.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLANMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSEIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     SVEETDTRPN"
     gene            complement(3659..4273)
                     /locus_tag="ACOIAP_000704"
     CDS             complement(3659..4273)
                     /locus_tag="ACOIAP_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGZ2637617.1"
                     /translation="MNEKWLEWAIELQSIAQAGITYGKDIYDRERYERIREISAEIIA
                     YKTDISTEKVRNLFCNESGYQTPKLDTRAAIFENGKILLVKENTGKWSLPGGWVEVNL
                     SVKENTIKEVKEEAGLDITADRIIAIQDRAKHNLPIYAYGVCKIFVLCTVIGGEFKEN
                     IETTEFSYFSENELPELATEKNTEEQIKMCFKACRTDTWTVIFD"
     gene            complement(4341..4703)
                     /locus_tag="ACOIAP_000705"
     CDS             complement(4341..4703)
                     /locus_tag="ACOIAP_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGZ2637618.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDEALKPFVETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQE"
     gene            complement(4923..5387)
                     /locus_tag="ACOIAP_000706"
     CDS             complement(4923..5387)
                     /locus_tag="ACOIAP_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGZ2637619.1"
                     /translation="MTRISNITIAEQSEYCILAIRKTIDFVVEFSEFSKQSLEKISKY
                     LEERGILSSGAPIVCFHNMDLAELDVEVGFPVATYIDGKNEILQRIIPSQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(5697..7118)
                     /gene="nhaC"
                     /locus_tag="ACOIAP_000707"
     CDS             complement(5697..7118)
                     /gene="nhaC"
                     /locus_tag="ACOIAP_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGZ2637620.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNVFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPVGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLKLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDI"
     gene            complement(7148..8212)
                     /gene="orr"
                     /locus_tag="ACOIAP_000708"
     CDS             complement(7148..8212)
                     /gene="orr"
                     /locus_tag="ACOIAP_000708"
                     /EC_number="5.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine racemase Orr"
                     /protein_id="HGZ2637621.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEVV
                     KAICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFYNVREIIKLKNIKIIGIATNLT
                     CYGAIIPSRENIGRLASIAQKMEGKFGINLEIVSGGNSSSIHLMTNDNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGFDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDSVEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(8197..9606)
                     /locus_tag="ACOIAP_000709"
     CDS             complement(8197..9606)
                     /locus_tag="ACOIAP_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlmL-related ornithine degradation protein"
                     /protein_id="HGZ2637622.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHNIDTNNPVFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDNIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQVTSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNIENQEEVRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKIKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(9606..11810)
                     /gene="oraE"
                     /locus_tag="ACOIAP_000710"
     CDS             complement(9606..11810)
                     /gene="oraE"
                     /locus_tag="ACOIAP_000710"
                     /EC_number="5.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ornithine 4,5-aminomutase subunit OraE"
                     /protein_id="HGZ2637623.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYR
                     DCTKPLKDSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLRIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELREKARELKERAVLYMEEIFEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDKNAIDNPSILIDGCTFENPDKIIYIDELDDFDNVENRLKESDEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQETEVISREVMHESEGTRIEVKGRV
                     PFDIDLKNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMNNK"
     gene            complement(11804..12178)
                     /locus_tag="ACOIAP_000711"
     CDS             complement(11804..12178)
                     /locus_tag="ACOIAP_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HGZ2637624.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVNGEYWDEVTCLFREGVESC"
     gene            complement(12256..13686)
                     /gene="ortB"
                     /locus_tag="ACOIAP_000712"
     CDS             complement(12256..13686)
                     /gene="ortB"
                     /locus_tag="ACOIAP_000712"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtB"
                     /protein_id="HGZ2637625.1"
                     /translation="MNNSASMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEVIQSQYAVGNTPIIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKKMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVIDVLNSL"
     gene            complement(13679..13987)
                     /gene="ortA"
                     /locus_tag="ACOIAP_000713"
     CDS             complement(13679..13987)
                     /gene="ortA"
                     /locus_tag="ACOIAP_000713"
                     /EC_number="2.3.1.263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-oxopentanoate thiolase subunit OrtA"
                     /protein_id="HGZ2637626.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVSNE
                     "
     gene            complement(14085..15152)
                     /gene="ord"
                     /locus_tag="ACOIAP_000714"
     CDS             complement(14085..15152)
                     /gene="ord"
                     /locus_tag="ACOIAP_000714"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-diaminopentanoate dehydrogenase"
                     /protein_id="HGZ2637627.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKILFLLNRKINVIS
                     TAEQMAYPQADDVDLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGATREEFIKGVEDKTIAGHVGFVESINMIADGLGWRL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(15412..16812)
                     /locus_tag="ACOIAP_000715"
     CDS             complement(15412..16812)
                     /locus_tag="ACOIAP_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HGZ2637628.1"
                     /translation="MNQEIFFKIMNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMN
                     RHDILTNSFFDIVNKMKINRSTLLEVLEKREIIKDNIQKYLDKNGKEITAINTTIPID
                     IKGEFVGALEISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAI
                     EKSKKACKSDASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGIL
                     FGTSKGGFTGAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTK
                     DIPIDVRIIATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFI
                     SKYNKKLNKRVIGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINL
                     NDYYNLKENKESKNYSLNDLEDKTLSKIISEIEEKYIYESLEKTSYNITKAASILGMN
                     RQNLQYKIKKYNIKIL"
     gene            complement(17319..19277)
                     /locus_tag="ACOIAP_000716"
     CDS             complement(17319..19277)
                     /locus_tag="ACOIAP_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2075 domain-containing protein"
                     /protein_id="HGZ2637629.1"
                     /translation="MKRAYYSSSVNEFIGKDIFTIFGEITCNDQFEANDLQKNTWKKE
                     IEILKRELSTFKDGHLLFEYTIPRIGSRIDNVLIYKGIVFLLEFKVDEDTYPRYAIEQ
                     VTDYALDLNCFHKESHDKLLVPILICTKAPQRNQRIRLMKENILETYCSNEFNIGKYI
                     EEVCTTYNKSSFNPDAWMDSLYMPTPTIIEAAQALYMGHNVEDISRNDASAKNLNQTT
                     KAINKIIDYSKIHNKKSICFITGVPGAGKTLAGLNIAIERQKVDENEHAVFLSGNGPL
                     VDVLQEALARDDVTRNGTRKTEAIRKAKEFIQIIHHFRDEAISVDTPPIERVTIFDEA
                     QRAWDEPNLTNFMKRKKGVLDFNMSEPEFLISILNRHIGWATIVCLIGGGQEINKGES
                     DGISGWFASLRNNYSDWDVYISNKIIDEEYSKGNSFDELTEGVNYRIIDDLHLSVSLR
                     SFRSEKVAAFVKAVLDVDKIAANELYNQFKKDYPICVTRDLELAKKWVRDKSKGSQRY
                     GMTASSGAKRLRKYGVWVQSKVDAKNWFLNGKDDVRASYFLEETATEFDIQGLELDWT
                     IVCWDGNLRFKNEQFEYYNFNGTKWQNINKEDNILYLKNAYRVLLTRARQGFVIFVPT
                     GDESDITMQPSFYNGVYEYLKEIGIEEI"
     gene            complement(19959..20291)
                     /locus_tag="ACOIAP_000717"
     CDS             complement(19959..20291)
                     /locus_tag="ACOIAP_000717"
                     /inference="COORDINATES: protein motif:HMM:NF013237.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HGZ2637630.1"
                     /translation="MYVLLSKYFTQKELAKKQLLNYTALLSFEIDAKDVNDIKKFVNK
                     LDLFKIGVSWGGHESLVFAPNIAILNEMTLEQAKALNVSPYTIRISLGLENSEDLIND
                     LNDALSIL"
     gene            complement(20338..20754)
                     /locus_tag="ACOIAP_000718"
     CDS             complement(20338..20754)
                     /locus_tag="ACOIAP_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HGZ2637631.1"
                     /translation="MRQYIHDKLREITEEEKNILEGNYIIDKSIYTDNSQFIIDSNKL
                     LNIDELIHIRKHTRFTQFPKHKHNYIEFNYVYRGKLVQTIDEYKINLKQGELIFLNQH
                     VIHEIEASNEEDIIINFIINQSFLIILYLCWKMIIQ"
     gene            complement(20735..21181)
                     /locus_tag="ACOIAP_000719"
     CDS             complement(20735..21181)
                     /locus_tag="ACOIAP_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637632.1"
                     /translation="MDCYIILIFYELLEIHKTKNEKTLTSDSKINIDNIAEMMKYIEG
                     NYAQTTLREVAKKFHFHPNYLSTLIKKTTGKSFKDIIHEQRLKKATTLLKSTDMSIED
                     ISIEVGYNNQTFFYKKFKETYSLTPKKYRIKSRILLKEVSHETIYS"
     gene            complement(21331..21798)
                     /locus_tag="ACOIAP_000720"
     CDS             complement(21331..21798)
                     /locus_tag="ACOIAP_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HGZ2637633.1"
                     /translation="MKDKTLEDILKQKTQAERYILECIDTNNVKKLDNKKIMSILHTI
                     LCWEEVNGTIVLTDKNILSLDEDIMVSKHHRFIDIPKHKHNFIELIYVYSGSCTQIID
                     GKETILKEGEICLLDMNVEHSINAVKENDIIINCIMRREYFDASFFLEFRLMS"
     gene            21984..22304
                     /gene="rhaM"
                     /locus_tag="ACOIAP_000721"
     CDS             21984..22304
                     /gene="rhaM"
                     /locus_tag="ACOIAP_000721"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HGZ2637634.1"
                     /translation="MNTVHKCFKMKLFKGFENEYKKRHDELWSEMIDMIHEYGGSNYS
                     IFLDEETNYLYGYIELKDAKLWDKSSETAICKKWWNYMSDIMETNEDNSPISIELKSM
                     FYLK"
     gene            23242..23817
                     /locus_tag="ACOIAP_000722"
     CDS             23242..23817
                     /locus_tag="ACOIAP_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2637635.1"
                     /translation="MSKIIAFVGSPRKNGNVDTIINEIIKGANKNKVDVKKYYLNDMN
                     IKGCQGCLYCRKNHSCSLKDDMIQVYEDIKKAEYVIIGSPVYICQVSAQTKLLLDRLY
                     PLTTIDKGKHIPRFGNKRIIMVYTQAAPLPIFFKRYFRYTSKHLKGMGLNHYKTIIAT
                     KAFEKNSIENNPKILKKAYNLGFKISKDINV"
     gene            complement(24487..24654)
                     /locus_tag="ACOIAP_000723"
     CDS             complement(24487..24654)
                     /locus_tag="ACOIAP_000723"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637636.1"
                     /translation="MNWKELWMTLFGTTEWFGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKGDAKESYK"
     gene            complement(24667..27432)
                     /gene="mgtA"
                     /locus_tag="ACOIAP_000724"
     CDS             complement(24667..27432)
                     /gene="mgtA"
                     /locus_tag="ACOIAP_000724"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HGZ2637637.1"
                     /translation="MNKKENRMAVRQTVEKTVIRDEQNRRIQFAATNPIKEVLKKFHT
                     TPRGLEVDAIPVSRAKYGTNKVTHEKKKSLAKRLAGAFINPFTAILFCLAVVSTITDM
                     IFPYFSLFGSVPEDFDYLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNQEKKEIPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTSIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLEAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEATDSRLTDLSENYVKVDEIPFDFTRRR
                     LTTVVQDKGGKTQMVTKGAVEEMLSICAFAECNGEVQPLTDDIRYRILETVANLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECEMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVADSTDVFAKLTPDQKVRV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIILNLIYDLSC
                     TAIPWDNVDEEFIAKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFLQSRAS
                     APVTLLTMTGITVLTIIPFTVFGTMLGFVALPATYFAYLIPCILLYMILATSLKKAYI
                     RHFGELL"
     gene            complement(27597..27908)
                     /locus_tag="ACOIAP_000725"
     CDS             complement(27597..27908)
                     /locus_tag="ACOIAP_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HGZ2637638.1"
                     /translation="MDFTCIFFGILFTFAGFWLAVGKGYRHLSLWKNMPKEEKDKINI
                     VPLSRNVGGIIALNGIIFLMKGVLPGFSNHWFIFSIIAWLIVASFDVWYIEKSVRYRN
                     Q"
     gene            complement(28292..28795)
                     /locus_tag="ACOIAP_000726"
     CDS             complement(28292..28795)
                     /locus_tag="ACOIAP_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HGZ2637639.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDYAKDLLSGIQEMIR
                     GEVSSLLLGSSEESDCPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYLLDNSNIMAFIRKLRKKIEPAPDSPTYILTIWGIG
                     YKFNDQI"
     gene            complement(28811..31474)
                     /gene="mgtA"
                     /locus_tag="ACOIAP_000727"
     CDS             complement(28811..31474)
                     /gene="mgtA"
                     /locus_tag="ACOIAP_000727"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HGZ2637640.1"
                     /translation="MSKATLFDSRIKKYAYCEISEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFLASNFARNATTAIII
                     FSMILISGVIRLIQELRAKSAAAQLDRLVHESVTVRRGGKLIEIPGEELVVGDIVLFS
                     AGDCVPADVRLTKITDLFISQAAITGESAILEKSCRKLSYGEQETLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKDSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITGGKWMESFAFALSVAVGLVPEMLPMVITACLAKGSLAMSKKQTIIKNINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDILGNENAEVLDLAYLNSSYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNYVEYHGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGISTERILTS
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLKLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIGFTYLTFAGGASLFGLTKLPLW
                     YFVFLLLVVFLYMLMNSVAKYFYKKKYQELI"
     gene            complement(31573..31719)
                     /locus_tag="ACOIAP_000728"
     CDS             complement(31573..31719)
                     /locus_tag="ACOIAP_000728"
                     /inference="COORDINATES: protein motif:HMM:NF024055.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637641.1"
                     /translation="MSVRKLYEKVLASSIRAPNLEGMIEKFDKDLPHSNDTDLIELKN
                     AISK"
     gene            complement(32378..32608)
                     /locus_tag="ACOIAP_000729"
                     /pseudo
     CDS             complement(32378..32608)
                     /locus_tag="ACOIAP_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(32728..32929)
                     /locus_tag="ACOIAP_000730"
                     /pseudo
     CDS             complement(32728..32929)
                     /locus_tag="ACOIAP_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009273766.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            33432..34754
                     /locus_tag="ACOIAP_000731"
     CDS             33432..34754
                     /locus_tag="ACOIAP_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGZ2637642.1"
                     /translation="MLDMFITIVSSIIELWACKKVFDYTSKVKTSLINLYFLISTFII
                     ISTFYTNVGADNRILICIFVMFVFYKLNYDVNIYKCLIVLFSYWAILVCINALSMIVI
                     VSINNLSSMNILLNDNFYRYETIVLGNIVLIVLLYIYKFISNDLQVTKREIYMCIPIV
                     ANMISFFIFYKYILKLLDISSATKLDILIMVILLTFSNIALIYSLVKILKNNKKYIEL
                     TKLQEKINAENKYYSNIKKYYIKTKELNHDMKNHLICIKEMNKKNIDTSNYINNIEKK
                     LDEYSTVFDTGNITLNIILSEKKELCIEKEIDFTININFSDCNFIKEEDTCSIFANAL
                     DNAIEACEKIKNDDKKIKLQGMIVNKFFVIKITNTKSNDILLKKNTFLTTKEDKEFHG
                     LGIKSIKNSLEKYGGAISINFSENLFCLNMMIPIRKSQKDSNIAYENS"
     gene            34797..35384
                     /locus_tag="ACOIAP_000732"
     CDS             34797..35384
                     /locus_tag="ACOIAP_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HGZ2637643.1"
                     /translation="MIKSCADKIAFLFVLNQVIEKDDLEICSYGLEILLSSIINTLSS
                     LMIGLILGRLIYSIVFLISFCIIRQFSGGYHANSNKNCILIFNSIFFISMVLGIILND
                     SNPIPLFLVILSSFNFLSIFIFAPVCHANNPLNETKYKKNKLMSRIISITLFLIILLG
                     CKYLSFYNYVVYTFLALLWINLLLIIQIIINKKII"
     gene            35397..35531
                     /locus_tag="ACOIAP_000733"
     CDS             35397..35531
                     /locus_tag="ACOIAP_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HGZ2637644.1"
                     /translation="MKKILYHFMKACGVLAMFVAFLSANTTSLWHVYQPKTPEKLKKF
                     "
     gene            complement(35910..36194)
                     /locus_tag="ACOIAP_000734"
     CDS             complement(35910..36194)
                     /locus_tag="ACOIAP_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGZ2637645.1"
                     /translation="MIIIFVKMAKTFANKIINRKSKTGYKSEINCYTCEECCYCQYKS
                     SCIKRSNSKIPLENRTKNLQVSKLFYEKRKENLKRIISPEGFEPRMNRSI"
     gene            complement(36154..36804)
                     /locus_tag="ACOIAP_000735"
     CDS             complement(36154..36804)
                     /locus_tag="ACOIAP_000735"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGZ2637646.1"
                     /translation="MKCEIDFGIKIIYKDKIKIYHLKKLLKKLRKISKELNIVFVHEK
                     GKKKSIIQKSIEQLNNYIDRLKKYTKDLHIMGERNSYSKTDNDATFMRMKEDHMKNGQ
                     LKSAYNIQFGVDSEYIVLVSSGHQPTDTTTLISFLKSIEDHIKFKYPKIVADSGYEGE
                     ENYTFLERNNQLSFIKPANYEISKTRKYKNEIGRIDNMDYDEKNDYYICKNGKNFC"
     gene            complement(36829..37305)
                     /locus_tag="ACOIAP_000736"
     CDS             complement(36829..37305)
                     /locus_tag="ACOIAP_000736"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGZ2637647.1"
                     /translation="MYNNCMQKQNTIQIDYTTYGDNYQFKLPLNIDYMIPKDDSVRLL
                     SQIIEEMNLEKLYKTYSRIRGNKVTPRQLLKIIIYANMNCIYSSREIEKACKRDINFM
                     YLLGGASAPDHSTIARFRSIYFSQVSKNLIAQFTNFIGYNKEISKDTLLIDGTKIE"
     gene            37738..38307
                     /locus_tag="ACOIAP_000737"
     CDS             37738..38307
                     /locus_tag="ACOIAP_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HGZ2637648.1"
                     /translation="MNNYNSINNLQIGKTYSNDEIKEIFKCSTQGGMIKSNTTKTLVI
                     FSDHTKSIYDDIWYDNTLIYTGMRKKGDQVLKGNQNITLYESETNGIKVHLFETFVST
                     KHIYKGFVKLSGTPFIGEQEDVDGINRKVWLFPLKLINNIPIEKNLLEYNKNLKSKKA
                     RKMTQLELKDNIKNKTIYKNCYIKTICKR"
     gene            38401..38559
                     /locus_tag="ACOIAP_000738"
                     /pseudo
     CDS             38401..38559
                     /locus_tag="ACOIAP_000738"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(38917..39240)
                     /locus_tag="ACOIAP_000739"
                     /pseudo
     CDS             complement(38917..39240)
                     /locus_tag="ACOIAP_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430345.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
     gene            complement(39453..40814)
                     /gene="rlmD"
                     /locus_tag="ACOIAP_000740"
     CDS             complement(39453..40814)
                     /gene="rlmD"
                     /locus_tag="ACOIAP_000740"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGZ2637649.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEEACKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMNEFKDMLLGIDLKSELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKRYGYEIRMVKCMDMFPNTPHCETIVKL
                     VRE"
     gene            complement(40841..41563)
                     /locus_tag="ACOIAP_000741"
     CDS             complement(40841..41563)
                     /locus_tag="ACOIAP_000741"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGZ2637650.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYVSATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEIKLIEER"
     gene            complement(41563..41892)
                     /locus_tag="ACOIAP_000742"
     CDS             complement(41563..41892)
                     /locus_tag="ACOIAP_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HGZ2637651.1"
                     /translation="MPQIKIRGINEDDICKISEKMIDDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEIAWFDRGQEVQDTVARIITDSIRTNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            42222..43148
                     /gene="fba"
                     /locus_tag="ACOIAP_000743"
     CDS             42222..43148
                     /gene="fba"
                     /locus_tag="ACOIAP_000743"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0030388 - fructose 1,6-bisphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HGZ2637652.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(43763..45394)
                     /locus_tag="ACOIAP_000744"
     CDS             complement(43763..45394)
                     /locus_tag="ACOIAP_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2637653.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     KNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNKNNVVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLKGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNIIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(45876..46913)
                     /locus_tag="ACOIAP_000745"
     CDS             complement(45876..46913)
                     /locus_tag="ACOIAP_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HGZ2637654.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(46932..47717)
                     /gene="etfB"
                     /locus_tag="ACOIAP_000746"
     CDS             complement(46932..47717)
                     /gene="etfB"
                     /locus_tag="ACOIAP_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="HGZ2637655.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEYDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKIGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(47750..48883)
                     /gene="acdB"
                     /locus_tag="ACOIAP_000747"
     CDS             complement(47750..48883)
                     /gene="acdB"
                     /locus_tag="ACOIAP_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative isocaproyl-CoA dehydrogenase AcdB"
                     /protein_id="HGZ2637656.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAAGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(48931..50058)
                     /gene="hadC"
                     /locus_tag="ACOIAP_000748"
     CDS             complement(48931..50058)
                     /gene="hadC"
                     /locus_tag="ACOIAP_000748"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HGZ2637657.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTKLVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(50058..51284)
                     /gene="hadB"
                     /locus_tag="ACOIAP_000749"
     CDS             complement(50058..51284)
                     /gene="hadB"
                     /locus_tag="ACOIAP_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HGZ2637658.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEMAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLIEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(51299..52099)
                     /gene="hadI"
                     /locus_tag="ACOIAP_000750"
     CDS             complement(51299..52099)
                     /gene="hadI"
                     /locus_tag="ACOIAP_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HGZ2637659.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(52138..53337)
                     /gene="hadA"
                     /locus_tag="ACOIAP_000751"
     CDS             complement(52138..53337)
                     /gene="hadA"
                     /locus_tag="ACOIAP_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HGZ2637660.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKGQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            54031..55029
                     /locus_tag="ACOIAP_000752"
     CDS             54031..55029
                     /locus_tag="ACOIAP_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HGZ2637661.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENIVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLIKTEDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            55403..55930
                     /locus_tag="ACOIAP_000753"
     CDS             55403..55930
                     /locus_tag="ACOIAP_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HGZ2637662.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASIVAGIIGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            55957..56553
                     /locus_tag="ACOIAP_000754"
     CDS             55957..56553
                     /locus_tag="ACOIAP_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HGZ2637663.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAMFIKEKSSIKIRINTNG
                     LSDLIHNKKTAIMLKDVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPKEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(56618..58201)
                     /gene="asnB"
                     /locus_tag="ACOIAP_000755"
     CDS             complement(56618..58201)
                     /gene="asnB"
                     /locus_tag="ACOIAP_000755"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HGZ2637664.1"
                     /translation="MINLEEKYSTRKDTCMIKILEYNGHIRNWKVLCEELGIDSSLGR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYKTEN
                     GKLLYSSSIRKLMEQPGFVKELNEEMLQMYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIERYWKPEFHPDYSKSIEEWTDEIHTTLQKIMPEIKSEDETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEEWFDESKLAQQTTDILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNVYHKAKCYGENLKTFYI
                     GNTNIMKEDEKRKILKKYNPDVLPIKLTKRIYEETEELDTLTNMSNIDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRMPSEYKVKGGENKIAFRKAASKVLPEEIA
                     FRNKLGFIVPIRIWMADDKYNQDIRDKFNSEIADKFFNIDEINEIFNDYISGNSNNWR
                     KIWTIYTFLVWYEIYFVKC"
     gene            complement(58768..59604)
                     /locus_tag="ACOIAP_000756"
     CDS             complement(58768..59604)
                     /locus_tag="ACOIAP_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGZ2637665.1"
                     /translation="MNYIIKKVLNSSVVLVHDANDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDISVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSVDDLLFNQMKRSNPKEMSIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(59628..61094)
                     /locus_tag="ACOIAP_000757"
     CDS             complement(59628..61094)
                     /locus_tag="ACOIAP_000757"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGZ2637666.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGSKGWSVSDVAKAHFDVDV
                     KDYKSNNEITTRDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDTEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEGVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLAAQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEQDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDVTSGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRIDYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(61097..62959)
                     /locus_tag="ACOIAP_000758"
     CDS             complement(61097..62959)
                     /locus_tag="ACOIAP_000758"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGZ2637667.1"
                     /translation="MDYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVDRAQFQVVIGNSVVDVYDEILKVCPLDTNDSAIKTEEKINLGTRFIE
                     FIINIFQPLVFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLIAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPSIAYNAQVFPAILCVS
                     FLSIMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAVLPFMVATGMHKALTPYAINTIGKLGYEALYMTASLAHNISESGVC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAILGVVLSSAISGIFLG
                     LFTVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNIE
                     QSSIENVVEEEPIEGKEVNILVSPVEGKVIDLSKVSDELFASKTLGEGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNSNGADYDYKVLNQSYGNVTKGSILFDVKGGI"
     gene            complement(63206..64069)
                     /locus_tag="ACOIAP_000759"
     CDS             complement(63206..64069)
                     /locus_tag="ACOIAP_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HGZ2637668.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDKVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFVKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKVIWEIFNNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(64124..65056)
                     /locus_tag="ACOIAP_000760"
     CDS             complement(64124..65056)
                     /locus_tag="ACOIAP_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGZ2637669.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKYVISHDYEYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENSLDEFTTLTEATHWSGTTYGGES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEHLKTLLCVGGVHFEK
                     SFSDIIKNKEFNISIGHVLPNQWIVSGMYDDESGLEKLEKCINSIADGIDGIVFHDKL
                     KGTYKEQCRKLGEKLNIPVFKHKILKNPKDLPIW"
     gene            complement(65142..65693)
                     /locus_tag="ACOIAP_000761"
     CDS             complement(65142..65693)
                     /locus_tag="ACOIAP_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637670.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDVDHFIEDDGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYVVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYV"
     gene            complement(65918..66409)
                     /locus_tag="ACOIAP_000762"
     CDS             complement(65918..66409)
                     /locus_tag="ACOIAP_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637671.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMNDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(66437..66997)
                     /locus_tag="ACOIAP_000763"
     CDS             complement(66437..66997)
                     /locus_tag="ACOIAP_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGZ2637672.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVNNWIDIEKIIKQGI"
     gene            complement(67149..68306)
                     /locus_tag="ACOIAP_000764"
     CDS             complement(67149..68306)
                     /locus_tag="ACOIAP_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HGZ2637673.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVLIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDNILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASRNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKSRTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(68343..69284)
                     /locus_tag="ACOIAP_000765"
     CDS             complement(68343..69284)
                     /locus_tag="ACOIAP_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637674.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDKKKNEEISNNKNL
                     NNKQNKNIQNKESNEEGSNNIKEKNNSDSNVSVNNKSEKQEDTTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNTETNSIN"
     gene            complement(69371..70063)
                     /locus_tag="ACOIAP_000766"
     CDS             complement(69371..70063)
                     /locus_tag="ACOIAP_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGZ2637675.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYENMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(70172..70984)
                     /locus_tag="ACOIAP_000767"
     CDS             complement(70172..70984)
                     /locus_tag="ACOIAP_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGZ2637676.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(71035..71946)
                     /locus_tag="ACOIAP_000768"
     CDS             complement(71035..71946)
                     /locus_tag="ACOIAP_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2637677.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYIFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVRIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIKAGKIELNNEIFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLHQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(72005..72736)
                     /locus_tag="ACOIAP_000769"
     CDS             complement(72005..72736)
                     /locus_tag="ACOIAP_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HGZ2637678.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFEKLNDVYKSLPVGNCLGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTKKNPCPFKDNNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMTLDSNIYSSGCIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEPEIRKRTIDRIKRIILV"
     gene            72825..73076
                     /locus_tag="ACOIAP_000770"
     CDS             72825..73076
                     /locus_tag="ACOIAP_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637679.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            73310..73729
                     /locus_tag="ACOIAP_000771"
     CDS             73310..73729
                     /locus_tag="ACOIAP_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637680.1"
                     /translation="MQIYFRVKAIGKRKPMLKLAPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIVNFLTNEEIESQANIGRVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSPINLKSGDIFTFIRLTLLAGRMF"
     gene            73754..78811
                     /locus_tag="ACOIAP_000772"
     CDS             73754..78811
                     /locus_tag="ACOIAP_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HGZ2637681.1"
                     /translation="MLERTRVEKNPKIIENLKNNFTKSSSKQYYDLAKPLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISSYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQEVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMISKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEVYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETSFDLSNTPIDKDFNARKEQFESLKHTLENLNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNREIVLTLLRKLELTDMELDKITNLLSLKTSSIRQTVIKILLEQDDSKLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTDRKELYKKLILLIKDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDNSPSLSKLDKIISNTSLSTNEDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLNLDYKLILDILFYSISTCGYNEIEKSWF
                     SSIYSNVLDSKKQNKISTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEVYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTKEQVNREMISGYNATNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPQSFMDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACAIAMENLA
                     RSAGFEDINRMMWALETEKLNEVAYIFKPKNIDRTSLWIDVDEKGKTSIKVQKGDKAL
                     KSVPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGEIYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQVQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PIIFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKVNNVNFEGSHA
                     LIEGTLGEYSVHMGSGIVHKKGIGALNILPVHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            79186..81693
                     /locus_tag="ACOIAP_000773"
     CDS             79186..81693
                     /locus_tag="ACOIAP_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637682.1"
                     /translation="MSIILATSLVVGIGTLSRSAQQADVDRLKRELGTDHVYFKNIKK
                     NQLKSIKSSKDIKNLGITSYYTSTDVNEKLPINILYANKNYLTSHSKLIKGRFPKASN
                     EVVVEKWILNSMGLKPEINQNLTFKLYQKENPETFKVVGILEDRFIEKQKGQCEIFSN
                     LNESKLNDFTTYIEFNEGSDINTNIDNIIKNAMLDEKSIGRNSMLIESTMKNGTLDNA
                     SKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLRAIGSTNFRIFKLMLYELFILALI
                     AMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFVIPDKIILLSIACTILIILIISFF
                     TYLKIRRISPIDAIRKTFGADKNVTTVNYLISKLTLNMSVTKSISAKNIFRNKKGFII
                     IVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYMNADFILSNVYLNEIGSNTSFKDI
                     KGFSDSQIDKIKNIDGIDKVKTASILNTRIEVNKINRLDYYEAINSNPYYKLNPLFIK
                     NKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINLKEMKKENLAIVYVPEISKTQKYT
                     KTFTPGEGTPAIDIKVGDTIKVKYPKGGMDTGLYESLKDNYEYLEYEFRVGAIISYTF
                     ADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYADLNENANKKKINNLLGKIGSEVS
                     GTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFIISVLNIINNISYNLTSRTSEFGML
                     RAIGISERGFKNMILYEGILYGVLSSIITIVSGLIIQFKMYYTQGFVSYGLGFSIDYK
                     IYILVVVANIIVGILATYIPSRKINKISIVEAINITE"
     gene            81705..82376
                     /locus_tag="ACOIAP_000774"
     CDS             81705..82376
                     /locus_tag="ACOIAP_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637683.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVAGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIEDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKVDKIISIIDGE
                     LKLTL"
     gene            82403..82744
                     /locus_tag="ACOIAP_000775"
     CDS             82403..82744
                     /locus_tag="ACOIAP_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637684.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(83097..85739)
                     /gene="adhE"
                     /locus_tag="ACOIAP_000776"
                     /gene_synonym="adhC"
     CDS             complement(83097..85739)
                     /gene="adhE"
                     /locus_tag="ACOIAP_000776"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGZ2637685.1"
                     /translation="MEKKENVVEKSSVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNAKIVGQPAHIIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTASSGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGNTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLEGLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        28643 a        14861 c        10598 g        32283 t
ORIGIN      
        1 caagttagtt tgagaaagtt attttaattg tataattgtt attacattta taaaatatgg
       61 cacatttaaa attattttgg tattggtagt attaatataa taaatattat aaaagctata
      121 aattataaaa tttaatataa tttatagctt ttactctttc aaatattatt ttttattgac
      181 ttattaatca attttattaa caggttacat ttatataagt aaacacttaa ataataaata
      241 tataatctac atatctataa gctgagtcaa ttcaccagta tatgtcaact taagtttgtg
      301 catagctcgt gtacaagcaa tatacaacaa actacggtca tagtcactat agtatgtttt
      361 actgtttact gaaggtataa taacttcatc aaactctaaa ccttttgaca ttttaataga
      421 agttatggac actccttttg taaaactaga actttcagaa gatattaagt taacactata
      481 ctcttgtttt aaagcattat atataacctc tgcatcacta tctgtcttta atataatacc
      541 caaagttgca ttatcacttt tcttaaactc ttcaatttct atttttatct tagatacttc
      601 atcttgttta ttagtacatt taactaaagc tggttcttcg ccatgtcgtt caataggctc
      661 taaagaagat acatcttgaa ccttctttgc aaaattaata atctcaaaag tagaacgata
      721 actcttgttc aatgtaacta gttctccttc attatatagt tgtctcatat catctagtgt
      781 atgagtatga ttaggattaa ccaattgtcc aaagcctcca agaatagtct ttttacactt
      841 aaaaagtaag tttattacag catattgaat aggagtatag tcctgcattt catcaataac
      901 aacatgtctt ataatcttat cttcttgtat cccttcatat gcagcatgaa tatatataaa
      961 tgggtataca tctgaccatt caagagtttt ctttgttgcc ataacaaaca tatttgatag
     1021 attcatttgt ttaaagaaat ccttatatag tgtaagagta ttttttattg tcaacattcc
     1081 attcaaactt ttaagtatac tttttaactt tggtaaatcc tcttccataa tattatctga
     1141 ctcaaactta taatgaatgt cttcagctac cttctctaat cttttcttaa ctggatatct
     1201 attatatgcc tcaaatctac tctgtatcca gtcactttta gctgtaaaac ttccaaaatt
     1261 gtagtctttt gggataaaaa tcttatttgg catttgtttt atataataat caataagttt
     1321 tacaaaatca aatgtagatt taaagcgcac tctttcagcc catttagcat catttatttc
     1381 taatgggtct ttctcacttt caaaattaat aactctatct aattgtacct ctgctatatt
     1441 ttcaaaactt aattcacata atggctcttc tccaagctcg agaaggacat tggaaatata
     1501 gtctccaaag actttattcg gtgataggat aattacattg tttgctgata ttttatcttt
     1561 aaatcgataa agaagaaaag caattctgtg taatgctata gatgtttttc cagaaccagc
     1621 taccccttga ataattagtg tatgagcttt atcatttcta ataatttgat tttgttcctt
     1681 ttgtattgtt gaaataattg acttcatctt ttcatctgaa gtgtgactaa gctccttttg
     1741 aagaatatca tcttgtatat taatggaact ttctaatgcg tattccaatt ttccattttt
     1801 aattttaaat tgtcgttttc ttgttatttc tccatccacc catcctattg gagcatcata
     1861 tcccgctttt cctatttcat aatcataaaa catactagca attggagaac gccagtcaag
     1921 tattataagt tcatcttcat aatcaaatgc aaatctacca atataatact tagattcatc
     1981 atccatatct tttagcctaa aatctattct agcaaagtat ggagaatctt taattttatc
     2041 aatcttatct cgaactttta ccataaaagc cccatagtta tctatttgtt ttagcccctg
     2101 ttcattttga aacatttcat gtgggtctat ttcaccacga ttttttacca tatacatttt
     2161 agtatccata taatccttgt caagcttgtc aacaaggttt tcagctttct taaaagcatc
     2221 atctaactta ttatttatat ctattagatg tgcaatctca tctggaaaaa aagttaataa
     2281 ttctgtatca tgttcataca tattgtgttt agaattggat gcaatagtat cacaatttat
     2341 cacttgttta tcttcaaaca tttaaatcct ccttgtaatt aagtacttac actgaatcat
     2401 tatacttaat tgtgctttga agtttttaat tattcttgct atttaactta aatattaact
     2461 ttaaaattca tttttctaaa actaaatctt tttatactta taagcataag tatatttaca
     2521 aacaaaatat gttgaaaata aaaacactct tatatataaa ttaattcaaa caaaaaatat
     2581 gtagtaaact ttttatttaa tctactatta atttggtcta gtatctgttt cttctacaga
     2641 aggaagaata aatttttgag taggataccc aaattccaca agtaattctg cttctgcaaa
     2701 acccaacttc tttatcatat ctctatgacc tgtatcagct ttatcacctt ctcgaaaagt
     2761 agtaattgag atatcagtat ctatcaaaaa atcttcaata actttcttca aaaacacttg
     2821 tgcaatctct gaattacgat actgtggatg tattccaaaa aaatcaatgc ttctagtttc
     2881 tctattaaac accatatttg caatagctac attattaagt tttaatatta aagctctttc
     2941 ttctaaaata tactgttcta attgatatat atattcttcc tcttgcaaat ttggaaatcc
     3001 atctatgact aatctcacta aattcatcca taatggtata tcagacatat ttgcaagttt
     3061 aatttctttt tccaattcta gtacattctt tgaaaataag ttatcttttt tcaaaacaaa
     3121 tcttagctgc aaaggataaa attcttgttc tttcctatat ttatttggag attttttata
     3181 catagcttta aatatagaag tgaatgcctg ttgactttca tatccagcta tcaatgcaat
     3241 ttcaattatt ggtttctttg aaaataccaa taattttgct gcttctgtca actttcttcg
     3301 ctttatgtaa tcatgcattg tcagaccaac agaagttgta aaagttctat gtaagtgata
     3361 ttttgagtaa tgaacagcat tagcgactat atctaaatcc agcttttctg ataaatgctc
     3421 ctctatatag tcaatggcag ttatgacatt aattacttta taagacattg cagctttcct
     3481 ccttttatcc atgcaacatt atatcaatta taacttagtt atatttaaat tatctttcta
     3541 ttgatttgtt ttatcgtgtc ttgtagagag tgtaaaatgg cgtattcagt gtcaatcaat
     3601 gtgccgtcta cataaaagac gatttctttg taatccatta atttctcctt aaattagcct
     3661 aatcgaaaat cactgtccaa gtgtctgtac gacatgcttt aaagcacatt ttaatctgtt
     3721 cttctgtatt tttttctgtg gcgagttcag gaagttcatt ttcggagaaa taagaaaact
     3781 ccgtagtttc tatattttct ttaaattcac ccccgataac ggtacaaaga acaaatattt
     3841 tgcatactcc gtaagcgtat ataggtaaat tgtgtttcgc gcggtcttga attgcaataa
     3901 tcctgtcggc ggttatatct aatccagctt cttctttgac ctctttaata gtattttcct
     3961 tgactgataa atttacttca acccaaccgc ctggaagcga ccacttccct gtattttctt
     4021 taacaagaag tatttttcca ttttcaaaaa tagcagctct agtatcaagt tttggagttt
     4081 ggtatccact ttcattgcaa aaaagatttc ttactttttc cgtggatatg tcagttttat
     4141 atgctataat ttcggcggaa atttctcgta ttctctcata ccgctctctg tcgtatatat
     4201 ctttcccata agttattcca gcttgagcga tgctttgcaa ttctatcgcc cattccaacc
     4261 atttttcgtt cataaaatca cctcccgttt tccgaagaat atattataat tagttactga
     4321 ttagtaaaat ctatttttaa ctactcctgt tttgtatgtt gaacatattc tataattgta
     4381 ccatctggat gtctcaatgt catattatat cctgtaggaa cttttttctt atctcttact
     4441 acaactgctc cattatccaa taggtaactt ctccattcat caacagaatc aaccataaaa
     4501 gtagattttg tttctacaaa tggtttaaga gcctcatcag aaccagataa taataaaaca
     4561 tttcctattt gtgctagttc caacccaact tctttataag aaaaacgcaa agaacatttt
     4621 tcttttaaaa gattctcata aaaaggtatg gccttttcta tatcttgaat ataaaaacgt
     4681 gttaatatat cgtatatttt catattttcc ccctatatct ctatattatt tataaagtat
     4741 atcactctac aaattatata gcaataaatt aagcattacc ttttgagcat tttaagtgca
     4801 ctttcacaat atgtttgggg tacatcagaa tacataaatt aaatctcttt gatattattt
     4861 agtataaaat ttatacagta aatgtcctta ttatcaacta ataaacgaga atcttttact
     4921 ttctatataa tgggtaacat cattttcgta aggtattcac tagctggacg attgatatca
     4981 tttaaatatt ggtaatatat atcgccatga agtttatatc cattactatt tgcccatgaa
     5041 aataagtcct ctaaagtagg gtcttgtaat tcatagggcc ctaaatcaat tgcagttatt
     5101 attttctgtg aaggaataat tctttgtaaa atttcatttt tcccatctat ataagtggcc
     5161 acaggaaacc ctacttcaac atccaattct gctaaatcca tgttatgaaa acatacaatt
     5221 ggtgctcctg aggataagat tcctctttcc tccaaatatt tagaaatttt ttcgagactt
     5281 tgctttgaaa actctgaaaa ctctaccaca aagtcaattg tttttcgtat tgctaaaata
     5341 caatactcag attgttcagc tattgttata ttagatattc tagtcatttt attcctccat
     5401 tactttattt ttacctctaa tccttttata ccaaattaca caaaatttcg ctgtataaat
     5461 aattatttca tatgaatata aaacatagcc tccttccatt tcttatattg aaagtataac
     5521 aaaaataatc ttatgatgtt tgtcacacag tgctcttata gtagtacata tttaaaagac
     5581 ttgcctaatt ttaaggcaag tctaaaagaa atcttctttc tataaaaaat ttatacaaac
     5641 aattcaaata tcgaaatata agctactatc aaactataaa tttaaattta ctaatatcaa
     5701 atatcaaaat ttaaacaagt ttcaggctca tcttctattc ttgctatttt aaacttacat
     5761 gcaattaata ccagagatac tattggattt ataatattta acaaagcata tggaccatat
     5821 gttagtgcag atacacctaa tgttgctgtt atataagccc cgcatgtatt ccatggtact
     5881 aatggagaag ttaaagttcc actatcttct aaagctctcg acaacatctt aggatgtata
     5941 cctctctttt tatattcctt attatacatt cttcctggta taactataga tagatattgt
     6001 tcacctgcta ttatattggt aattgtacaa gttaccatcg tacataatac tgttccaaat
     6061 acacccttag ctaattttag taaagaagat gctactactt caagcatacc tgttttttct
     6121 aaaatacctc caagagataa agcacatatt gttaaagaca cagtggacat catattcata
     6181 attccgcctt tagataataa agcatctacc tcttgtattt gtgttgacga aacatatcca
     6241 ttttgtgctg catctaatat cgtattcata gattctcctt gaaaaactac tgcaaacaat
     6301 actcccaata cagcacctac tataagccct ggtatagcag gaactttaaa tacaactaat
     6361 ccaattacta ttgccggagc taataataat actggtgata aagtattaaa tgtagaatct
     6421 aatgtagacc taattaactc tatctgtttt atatctagcg cttgacctga atacttcatt
     6481 ccgattacac cataaattac taaacaaatt aataatgatg gtatagtcga atatagcata
     6541 tattttatat gtgtaaataa atctgttcct gccattgctg gagctaaatt agtcgtttca
     6601 gataaaggtg atagtttatc tccaaagtaa gctccagata ttatagaacc tactattagt
     6661 ccaactggca tacctaaact ttgaccaatt cctaaaagag ctactcctac tgtacccatt
     6721 gtactccaag atgaacctgt cgcaagagat actattgcac agactagtgt tgatgctact
     6781 aaaaaaacat ttggtgataa aatttttagt ccccagtaaa tcatacatgg aactactcca
     6841 cttactatcc aagttcctat aagtacgcct attataatta tgattaagat tgcctgcatt
     6901 gccatcttta tactattaaa catacttaat tctaactctt tccatttaaa tccaagtcta
     6961 tatacagcca caagtcctgc cactgctgca gctcctatta gtggtacatg aggtgatgaa
     7021 ccatatacta atactcctag acttaaaaat aatatcaaac aagtaattgg tatcattgca
     7081 tcaaacagac ttgcttttct acattctcgc tctttcataa aataatttcc tcctaattat
     7141 ttaaacacta cactataatt ttttttgaaa catatttact cgtactagat gacatgatac
     7201 caccataagt taataaaaat tctacactgt cacctaattt ataatcatat tttgtgttgc
     7261 ttacatctag tatcatgtgg tctgagcttg cccctaatat ttttatatca gtgtctattg
     7321 gaattaaaga gtcaatattt atatcctgtt taccgatggc tataattgcc ctttttaaga
     7381 ttcctttatc ttcataaaca ggcttatttc taaaagcatc aaatcctatt tctccaatag
     7441 gaactgatgg cttttcttta cattcaacta cttggcatat taatttaaat gcatcttgat
     7501 acgttccatt tatattttca ccgtatgccg tttctctacc aagtagaata gattcgccta
     7561 ttctcagatt agtaattcct tctggcatat tatcatttgt catcagatgt atagaacttg
     7621 aattgcctcc agatactatt tctagattta ttccaaattt gccttccatt ttttgtgcta
     7681 tacttgctag tctacctata ttttctctag agggtataat agctccataa caagttaaat
     7741 ttgtagctat accaattatt ttaatatttt ttaattttat tatctctctc acattataaa
     7801 aaaaatcttc ttcataaaaa tacccttctc gtaaatctcc taagtcaaac ataaggacta
     7861 tcttatgaat aatattttta ctttcacata attcatttaa tttctttatt gttcctaact
     7921 ctgagttaaa actaatatca caataattga taacttcttc taattcactt aacattggga
     7981 ttctaatcaa tatcttaggt aaatttatgt cttgtaaatt ttttaagttt tgtattcttg
     8041 aatctgctat atggtctatt ccttcactac atattgcttt tactacttct ttttgtgcac
     8101 aaaatgattt agtgacaaaa gatatcttaa tatttctttc gtgacacatc tgcgaaatta
     8161 attttgcatt atgctttaac ttttctatat ctatttctaa cctaggatac ataatctttc
     8221 ctcctcaaaa ttcaaacttt ttaataggag cttaagagat gcttcttcat attttttaga
     8281 taaaacaccc atagatgcca taatataatc attatctatc aatatctttg ttttttcctt
     8341 tggaaatagt aattcattat ttttattgta tttaagcata ttatctaata tttcaattct
     8401 actagggagc ctagtaagtg ctccccctgt accaactata tatcttactt ctgttaaatc
     8461 tttcccttct gcaattttga ttttcccagt tgttccatag atatttctta tttttcctga
     8521 atgtcttaac atagctttaa caacagcttc ttttgttaat ctctcaacaa ataatatttc
     8581 ttcttttgac tttggtattg gaggataatt ctctattact gcatcaatat ctatagataa
     8641 ttcactttgt aagttttctt tacctatcac ttccactata ttcttcatat ttacatatac
     8701 acctaaatca ccctcaacac tcctctttgc agtaggttca ggattaacta aaattttatt
     8761 aatatagtca cttccatctg taacagaatg tacatcagta gttgctccac ctacatccag
     8821 agttaataaa tctccaatat ttttatataa gagtttagaa gcttccatta cagctcctgg
     8881 ggttggagta atattttcat taaccatttc tttaatgtat ttcattcctg gtgctgtagt
     8941 tatgtgttct tcaaatacac tttgaatgat tcttcttgta ggttctatat tcaataaatc
     9001 tattttaggg tatacatttt cagttatata aagcttataa ttagtatctt caaatattaa
     9061 ccttacttcc tcttgatttt caatattccc agcatatata actggtatgc ctagattcat
     9121 agaagctatc atttctgcat tataaatagc tgtatctctt tctccataat cgactccacc
     9181 agctattaaa attatgtttg ggtttatttc ttttatttta tttaaatcag ttcttttaat
     9241 tctacctgat gttacttgac gaataacagc tccagcccct agggcagctt ctttagctgc
     9301 ttttactgtc atatcataga ctaatccatg aacagtcatt tttaatccac cagctgcact
     9361 agaagttgca aacatatcat tatactctat attatctaca gataatttat tagctaaatc
     9421 cttaatagca cctgataaac cgtttcttac atcgccacct tcaaacactg ttgttggagc
     9481 ttgaccttga cccaaaaata caggattgtt agtatcaata ttatggaaag cgtttaccac
     9541 agtagtagtg cttccaattt cagctaccaa cacatctatt tttaaggaaa ctttgctatt
     9601 ttccattatt tattattcat ttctcttctt ttttcaacta agaaagtggc tacatgtatg
     9661 cccttgctgt ttcttccaaa tccagcatct attccttgtt caacggctat ttcaggtgtt
     9721 acttgtgtcc ctccacacgc aatcattact ttatctctta tacctttttc cacacaataa
     9781 tcgtgtaatt tcttcatgtt tttataatga atatcatcat gacttattat tgtagatgca
     9841 agtattgcat ctgcattcag ttcaattgct gcatctacca atttttctac aggtacagaa
     9901 gtccctagat agtggcattc tataccatat ttttcaatac caccatgttt tatatctatt
     9961 atttctctta aaccaactga atgttcatct tctccaaccg tagctgaaac tattttcata
    10021 ggtttttctt ctatatctgc tcttatctct tcatcagtta ataccttagg ttcttctggt
    10081 attactaaat tttttaaatc tatatcaaat ggaactcttc ctttcacttc tatcctagtc
    10141 ccttcagatt catgcataac ctctctactt ataacctcag tttcttgtaa gttcattttt
    10201 ttgacaaact ccagagctgc aaattcagct gttcttttat ccgtaggaag catcattgtt
    10261 atcattacaa ttccatctgc acaccattcc atttcaggct taatcttagt tccatttcta
    10321 tattcatctg attcttttaa tctattctct acattatcaa aatcgtcaag ctcatcaata
    10381 tatattattt tatctggatt ttcaaatgta catccatcta ttaatattga tggattatct
    10441 atagcatttt tatcgtattg ggctacatta ttgtatccaa agtgagcagt tacaggtgct
    10501 aaataatctt cttctctttc ataaacagta ccttcaccaa ctcctccttt tatttttcta
    10561 gatattccat caccatttct ttctggataa tttcctgagt caacaaagaa tccttgttct
    10621 acagattcaa aatatccgcc aacttcaaat atttcttcca tatataatac agctctttct
    10681 ttaagttccc ttgctttttc tcttaattca ccgacatctt taagttctat catatccata
    10741 agaccatcca taccaactaa agcttgcttt gctgtatcac acgcttctat attatatata
    10801 tgccaaggta catttctacc ttcatcaggt gttatagttg attgtatgtc agctctagtt
    10861 aatactgatg ttaataagtt taatacatga gtaactgttg cctctctagt tgatgattcc
    10921 atatatttag tattcatttg agctctcatc ttataatcac taaataactc tctaagtgca
    10981 acagcataag gtaagtctat tcttaaacat ggtgctggag gtgctgttgg tggaactgtt
    11041 gataagcata tattactttt atctattcct attttttctg agaatataga gtttaaagcg
    11101 tgttgaacca taagttcagg cattaccttc catgcttctc tagcagtagc attagcatta
    11161 tgcgctccat ctatttgagc tatattagca aaagccatta tttttttagc ttcacaagca
    11221 tctacaaaag accttatcat atttatattt ctatatagaa cattgtattg tgggtcttgg
    11281 tgtgctccat tgactccttc ttcagcaaac attactgcta cttcaggacc agcaacacca
    11341 cttacatacg aatgataatt aataggtcta ccaacttctt cttctataaa atcaagagcc
    11401 tttctttgag ctcttacttg ttttcttgtt attggaactc cacctatccc ttggggagtt
    11461 ccttctataa gcccatcaaa atgtgattgc ccagcagttc taataaccat taaatggtca
    11521 gctccatgat gagctgccat cctcattctt cttatatcat cctcaaatct accagaagct
    11581 atttcagtag taataactgg gcttggttga gggtctatat tattgaaata cttagatgat
    11641 ggtagcccca cactgtcttt taaaggtttt gtacagtctc tatatttaaa aggtcccatt
    11701 tcaagatttt ccaaatgctc tctccaaacc caacctcttc tttttggttt atatttatcc
    11761 aaatctttta atatatagtc tatatccaat tttttatttt cctttaacat gattctaccc
    11821 cttctctaaa taaacatgta acttcatccc aatattcacc attaactaat agtaaacctg
    11881 cttctctaac tgttatattc ttagatttag ccaacttata aactacatgc cctgctcctt
    11941 tacctataag acctctttcc ataacccctt ccagaatagg ttttacttca agagaagaaa
    12001 atcccattct taacaagaca gacctttcta ttgatggtgt tgtattcttt ttaccaagtt
    12061 ctatcattgg ttctactatc tgggtagcta aactccaaaa cctttctttt aactcatcat
    12121 cactcagttc ttgaagatgt tttcttctaa cttcaaaatc atcctctctt tttttcatga
    12181 acattcctcc attcgtattg atttaatcga attttccgaa tttttatttt acattaaatc
    12241 aaaaaacaac aactactata aactatttaa tacatcaata acaaaatctc ttgaactttt
    12301 tacttcttcc attaaaaatt ctatatctcg attacttagc ttatcaatat tatcaatgtg
    12361 attattggat atacaatttt ttataaatga ctttcttatc ttattcatat caatatcaac
    12421 acatttcaat aattctggtc tttctggtaa tattaagttt actcctgcaa tttcttctct
    12481 tggatttcca aattttatat ctattccatt ttctcttgca aaagtaagtt gtggacatat
    12541 atgtttacct gcacctgtat attctgtttc ttgtaccact ataactttat cctcatctaa
    12601 ctcttgagct aaagagaatg ctgctgctaa agatgtattt cctgctggac ctctttctat
    12661 accttctagc tgtgccaata attcagttgt ataaaaaact tctccttgtt ttactaacac
    12721 atatctatcc atatatctaa gtggtctagc tgcagaccta ggtacatctg acctatcagg
    12781 ccatgtacag tatggtatac caaaacctgt atgtcctgtt gtaaatgatt ttttattaaa
    12841 ttgattatcg ctagccatgt gtaacccttt taaatctaca cttgctccta ctactttagt
    12901 attaatagaa ccagctttta tcaatcctct tgcagttcca gtaagattac caccacctgc
    12961 atttgtacaa acaactatat cagggtcttt tttatacttt tctctaaatt gtatagctaa
    13021 ctcataacct aaagtttcta cacctgcaat tccaaatggt gaatataatg atgcgttaaa
    13081 atagcctgtt tcttctaata aaactaagaa cgtataaaat aactctggtc caacagttaa
    13141 ctgaacaact tctgctccat atgcttcaca ttttcttgct ttttctataa tttcaggctg
    13201 acctacacca ttagaatcat aacactcttg aactattata cattttaatc cttgcattgc
    13261 agcttgggat gctacagctg caccatagtt accactagta gctgctatta cacctttata
    13321 tcccattttt ttagcatgat atactgcagt agctgctctt cttgctttaa aactaccaga
    13381 tgcattcatt gcttcatctt ttacaaatat tctagctcct ttaccttctt tagcacattt
    13441 tctagctaat ttagtcaaat ttttaagctc tattatagga gtatttccaa cagcatattg
    13501 tgattgaatt acctcaatat cttgtaatgt atatcctgtt tcactcatca tcttctcata
    13561 atcaaaccct attccttctt gttcaaaaga agagtaatcc aatccaattg catttttcat
    13621 tatttcgtta tttcttccca taacagcttg ataactcata tctttcattg atgctgaatt
    13681 attcattaga tacacctcca aataatattt ctttagcttg gattcctatt tggagtaact
    13741 ctggtataca tttaccataa tcatgagtat aatatgggtt tactttaagt aaattacctt
    13801 ttacaagtct acctgtaatt gttttaactt ctactaagtc gcctatagaa gcatcacttt
    13861 gtataaaacc tttaacccac atttctaagg atactttctt agtatcctct ggaacttgtg
    13921 gagctctttc ttctggagtc aatactatat tgtgtataat aacccaatca ttaattttag
    13981 catccatttt ttcatcccct tattaattga ctattgtctt actaattaat ttactgttat
    14041 tttaaattaa ctattatttt accaattagt tagctgttat cttactaatt agccttcgat
    14101 tcttcttcca attcaacttc tatctgattt cttatatctc ccattattgc tctaggtact
    14161 ggtatatcca acatagtttt aagacctggt ctagcattta ttattaatgg aatagagttt
    14221 actatcattg cataagtacc tactcctcca ggtatttcag gatttatttg taaatcaatg
    14281 tttggtatac cttttattga tacataatcg cctgttttaa tgccttccgc ttctggtatt
    14341 atctgttgtg gatgctccat ttcaattaaa acttctccat ttacatatcc atatccacat
    14401 tgtctacaac cagcaacatt tccagccaat gcctctccgt acttagattt tctatctact
    14461 gtagtcatta ttggttcttt tgtttgttct atcttatcta gtctccatcc taatccatcc
    14521 gctatcatat ttattgattc tacaaaacct acatgacccg ctatagtctt atcttctaca
    14581 ccttttataa attcttctct tgttgctcca acaccttgtt ctaccataac agactttcca
    14641 aatggagata aatcatttac tctcttagct tttatactag taacttcttc acaagtacct
    14701 gaaagtgcta atactagtaa atctaataca aaccctggat ttattcctgt tccaagtata
    14761 cttactccat tttcctttgc aacttcatcc atttttttag ctaaatccac atcatcagct
    14821 tgtggatatg ccatttgttc tgctgttgat ataacattta tttttctatt taataagaat
    14881 agtattttat caaaagcctt tttagtaaat gaatcagttg ccaataaaac aacatctacg
    14941 cttttttctc taaaaacttc ttcataattt ttattgataa taacttctgg tctttctcct
    15001 ctttcaattc ctaagacatc atacatactt ttccctgaag tacttctact acaaacagat
    15061 actatttcta taccttcttt ttttagaatc atattagcca tacctattcc catagctcca
    15121 aatccccata ttcctactct tacttttctc atatatacac cctcctaaaa atttatatat
    15181 tctcaataat tagttaaagc ataaatcgtg ccaactttaa aattaaaata aatatttatt
    15241 agagtgttga aactataatt actttattac gtattttcat aattaaaaaa taatatttct
    15301 tctgaaaaat aaaaaaaaga gcaaaatatt ttgctctttt ataataattt tgctccttta
    15361 ttttgctttt ttactttact ttgattgttc ctctattttg ctctttttta tttataatat
    15421 tttgatatta tattttttta ttttatactg taaattttgc ctattcatac ctaaaattga
    15481 tgcagcttta gttatattgt atgatgtctt ttctagcgat tcatatatat atttttcttc
    15541 tatctcacta ataatcttac taagtgtttt gtcctccaaa tcatttaaag aataattttt
    15601 actctcttta ttctctttaa gattgtaata gtcatttaaa ttaatcatac tcgtttctat
    15661 ttgtacctcg tcttccatca tactcatagt acaataaatt atgttttcta gctctcttat
    15721 gttaccttgc caatcgtaat tttttaaaat tttaatagct tcatctgaaa tgcctattac
    15781 tcttttattt aactttttat tatattttga aataaatttt ttgcacaata gaggtatgtc
    15841 ctcttttcta tctctaagag gaggaatttt tatatgaatt atgttaagcc tataatataa
    15901 atcttttctc attttatgct catttaaaat gacctttgga ctttcatttg tcgttgcaat
    15961 aattcttaca tctataggta tatccttagt tcctccaact cttcttacat aaccttcttg
    16021 taaaaccctt agtaatttag cctgtaacat aatgggcata gaatttattt catctaataa
    16081 caaagttcct ttgttagctt gctcaaataa gcctggccta tctattgccc ctgtaaatcc
    16141 tcccttgcta gtcccaaaaa gtataccttc gaatagtgat tctggtaaag ctgcacaatt
    16201 ttgtgctata aatggatagt ttctcctatt acttccatag tgaattgact ggctaaataa
    16261 ctctttgcct gttccagttt caccatatat aaatactgaa gcatcagact tgcaagcttt
    16321 cttagatttt tctattgctt ctttaatcaa attactttcc cctaaaatat catcaaattc
    16381 atagcccttt ttttgtctac tactaacctt attgactaaa ttttttttat agtttctatt
    16441 tagtaaattt tctatagttg tcatattttt tgatatttca agtgccccta caaactctcc
    16501 tttaatatca attggtattg tagtattaat tgctgttatt tcttttccat ttttatctag
    16561 atatttttga atattgtctt tgataatttc ccttttttcc aaaacctcta atagtgtact
    16621 tctgtttatt ttcattttgt ttactatatc aaaaaatgaa ttggttaaaa tatcatgtct
    16681 attcattttt tccatttttt gtacagaatt attgtagatt atagttttcc cgtctttatt
    16741 aacaaaatgt accccttcat caatattttc caatatttca ttcattattt taaaaaatat
    16801 ctcttggttc aactatatca ccccagtacc taaatatata aaaacccaaa aaattaataa
    16861 aatatttcca ttgtatttat cttatcatat atttatgata ttttttatgt acattatatt
    16921 aatatatttt taagtatatt taaaatttta tttatatatc tttcattatg gttatacaat
    16981 agttgaattg tcattaaatt tgccaatagt tttatatatt attgatttta ttaaaaaaaa
    17041 agatatacaa actaataagt tgtaatctct tttaaactct aaattaaaat tattttatac
    17101 aatataatta aatatattgc ttataataaa aaccatattt aaattttaga ttggttgaaa
    17161 attattaata ttcatttctc aactcagctt gcttctcttc ttttttcttg ttatctcttg
    17221 aatgtattct ttagttacaa ggttttactt ttctcatata ttataaagaa aaatagtttt
    17281 ttacaaataa tccatttaat actatcctta cttccaacct aaatttcctc tattccaatt
    17341 tcttttaagt attcatatac gccattataa aaacttggtt gcattgtaat atcactttca
    17401 tcacctgtcg gaacaaatat aacaaaacct tgtcttgccc ttgtaagaag aactctatat
    17461 gcatttttta agtatagtat attatcctct ttattgatat tctgccattt agttccatta
    17521 aaattatagt attcaaattg ctcattctta aatcttaagt ttccatccca acaaacaatt
    17581 gtccaatcta gctctaagcc ctggatatca aactctgtcg cagtttcttc taaaaaatat
    17641 gaagctcgta catcatcctt accattaaga aaccagtttt tcgcatcaac tttactttgt
    17701 acccaaaccc catactttcg aagtcgttta gcgccagaac ttgcagtcat tccgtaacgc
    17761 tgtgaacctt ttgatttatc tctcacccac tttttagcta attccaaatc cctagtaaca
    17821 catataggat aatctttttt aaactgatta tataattcat ttgcagcaat tttatctaca
    17881 tctaaaacgg ctttaacaaa ggctgctact ttttcacttc taaaagaacg taatgataca
    17941 gataggtgca aatcgtcaat tattctataa ttaacgcctt ctgttaattc atcaaaagaa
    18001 ttacctttag aatattcttc atcaataatt ttatttgata tgtaaacatc ccaatcagaa
    18061 taattatttc ttagtgatgc aaaccaacct gatattccat ctgactctcc tttatttatc
    18121 tcttggcctc caccaatcaa acaaacaata gtcgcccatc ctatatgacg atttaaaata
    18181 ctaatgagaa attcaggctc tgacatatta aaatctaata cacctttttt tcttttcata
    18241 aagttagtta aattaggttc atcccatgcg cgttgtgctt catcaaaaat tgtgactctt
    18301 tcaataggtg gtgtatcaac agatatagct tcatctctaa aatgatggat tatctgaata
    18361 aattcttttg cttttcgtat cgcttcagtt tttcgtgttc catttctggt tacatcatca
    18421 cgagctaatg cttcttgtaa aacatcaact aatggaccat ttccagaaag gaagactgca
    18481 tgttcatttt catctacctt ttgtcgctca atagcaatat taaggccagc aagcgtttta
    18541 cctgctccag gaactcctgt gataaaacat attgattttt tattatgaat cttactatag
    18601 tctataattt tatttatagc tttagttgtt tggtttaaat ttttagcact tgcatcattt
    18661 cttgaaatat cttcaacatt atggcccata tataaagctt gtgcagcttc aataattgtt
    18721 ggagttggca tgtataatga gtccatccaa gcatctggat taaatgaact tttgttatat
    18781 gtagtacaaa cctcctctat atactttcct atattaaact cattactaca ataagtttct
    18841 aaaatatttt ccttcatcaa tcttattctt tgatttcttt gaggagcttt tgtacaaata
    18901 agtattggta ctaaaagttt atcatgactt tccttgtgaa aacaattaag gtcaagggca
    18961 tagtctgtaa cttgttcaat tgcataccta ggataagtat cttcatcaac tttaaattca
    19021 aggagaaaaa caatgccttt gtaaattaac acattgtcaa ttctactgcc tattcgtggt
    19081 attgtatact caaataataa gtgtccatct ttgaaagttg agagctctct ttttaatatt
    19141 tcaatttcct ttttccatgt attcttttgc aggtcattag cctcaaattg atcattacat
    19201 gttatctcac caaatatagt aaaaatatct ttacctataa attcatttac gctacttgaa
    19261 taatatgctc ttttcataca tcctcctcct ttatatctaa ttaaccttat agtctacatc
    19321 tatcctacag tctaaactat aacccctatg atatcaatcc tgtagtctaa aatctgactc
    19381 ctatactcta taaatacact gaatagatat gtttatgtat ggtactttga taataatttt
    19441 tctttgctaa gtaaattatc aaattttcaa caactatgga tatttctgaa aaatggactc
    19501 agaaaattag aaattggact caaattttag ctcatttaag tatttatttt gaataaaaaa
    19561 atttaactct aagttaataa acaagcattt caaaaaatca aaaagttttc tgaaagtgat
    19621 aataattttg caaaaataga aaaattcaaa aaaggctata atttttaaag tcatagcttt
    19681 accaataaat gtttacttgt cacttaaaaa ataaagtttt gtttaaagaa tacatataaa
    19741 catttccaga ctcagattta tttaaaattt atttactaag aagtttgata ctttctccat
    19801 caccttttgt acaataagtt atgtgatatc ttataacact catctcaagt caataaaata
    19861 ataataaatt ttattatata ctagcaagac ttatcaaaca aaaagaaaaa acatatagac
    19921 tatttagtta atatgttttt ccatatattc ttattatatt ataaaatgga tagcgcatca
    19981 tttaaatcat tgattaaatc ttcactattt tcaagaccta aacttattct aattgtgtat
    20041 ggtgacacat ttaacgcttt ggcttgttct aaagtcattt catttaatat agctatattt
    20101 ggagcaaaca ctaaactttc atgacctccc caactcactc ctattttaaa taaatctaat
    20161 ttatttacaa attttttaat atcatttaca tcctttgcgt ctatttcaaa acttaataac
    20221 gcagtatagt taagcaactg tttctttgct agttcttttt gagtaaaata tttagataaa
    20281 agtacatata ttctccaaga ttataattag tatatagtgt agtcattaaa aagttcatta
    20341 ttgtattatc attttccaac aaagatataa tataatcaaa aaactctggt ttattataaa
    20401 attaattatg atgtcttctt cgttactagc ttctatttca tgaataacat gctgatttaa
    20461 aaatattaat tctccttgtt ttaaattaat tttatattca tctatagttt gtaccaattt
    20521 tcctctataa acataattaa attctatata attatgttta tgttttggaa attgtgtaaa
    20581 tcttgtatgt tttcttatat gtatcaactc atctatattc aataacttgt tgctatctat
    20641 tataaattga gaattatcag tataaatact tttatctatt atataatttc cttctagtat
    20701 atttttttct tcttctgtta tttccctcaa cttatcatga atatattgtc tcatgagata
    20761 cctcctttaa taaaatcctt gattttatac gatatttttt tggagtcaga ctatatgtct
    20821 ctttaaattt tttatagaag aaggtttggt tattatatcc cacttcaata gaaatgtctt
    20881 ctatactcat atctgtactt tttaataatg tagttgcttt tttaagtctt tgttcgtgga
    20941 tgatatcctt gaatgattta cctgttgtct tttttattaa agtacttaaa taatttggat
    21001 gaaaatgaaa ttttttagca acctccctta aagttgtttg tgcataattt ccctctatat
    21061 atttcatcat ttctgcaata ttatctatat taattttact atcagatgtt aaagtttttt
    21121 catttttagt tttatgtatc tctaacaatt cataaaatat taatataatg taacaatcca
    21181 ttatttcctt ataacacatt gatttattca aatattcctt agttagttca gctactagtc
    21241 gtttcaattt aaaattattt ttagcattaa atatataata attatcacat ctttttcctt
    21301 tgtgtatagc tcctgctaaa aaattatata ttaactcatt agacgaaact ctagaaaaaa
    21361 agatgcatca aaatattctc tcctcattat acaattaata atgatgtcat tttcttttac
    21421 tgcatttatt gaatgttcta cattcatatc caagagacat atttcacctt cttttaatat
    21481 ggtttctttt ccatctataa tttgagtaca tgaaccacta taaacataaa ttaattctat
    21541 aaagttatgt ttatgtttgg gtatatctat aaatctatga tgtttggata ccataatgtc
    21601 ttcatctaaa gaaagtatat ttttatctgt tagtactata gttccattta cttcttccca
    21661 acataaaata gtatgcaata tagacattat ttttttatta tctaactttt ttacattatt
    21721 agtatctata cattctaata tgtacctttc tgcttgtgtt ttttgtttaa gtatatcttc
    21781 tagcgtttta tctttcattt atatccctcc agaattagct atactttatt acagttttaa
    21841 attagattaa gaatattctt tatttaattg tatcatatta atttttgaca gtaataatgt
    21901 taaattatga catttaaaaa tacctttttt tgttttaaaa taaatttata agtaaacatt
    21961 taaaatttag gaggtatttt tttatgaata cagtacataa atgtttcaag atgaagcttt
    22021 ttaaaggatt tgaaaatgaa tacaagaaac gtcatgatga attatggtct gagatgatag
    22081 atatgattca tgaatatggt ggtagtaact attctatttt tctagatgaa gaaaccaatt
    22141 atttatatgg atatatagaa cttaaagatg caaaactatg ggataaaagt tcagagacag
    22201 caatctgcaa aaaatggtgg aattatatgt ctgatataat ggaaaccaat gaggataata
    22261 gtcctatatc tatagaactt aaatctatgt tttatttaaa ataaagacaa gaattattat
    22321 aaattataaa aatggggatg tatcaaaata aaaacttgag ttatctcctt ttttatataa
    22381 aaagagaagt gattcctaaa aacctctaac ctatattata attgttctgt gaaaaactaa
    22441 aaatacattt cgattatagt agctacaaat gctataaaca agtggtattt ctactagaca
    22501 ttgaaacaat tattctcaaa gataattcag taagactatt taacctaact ttagagtaat
    22561 tgatatatct tatgttgctg tttatattaa ttaaagtata taatttatac tatgattact
    22621 attttctttc aaacttagaa tatgttcttg ctaatttttt tatttctctt gcgttgcatt
    22681 ctttgtgttc ccttatatat gttaaaactg aataatataa ttatgtatta tctacatttt
    22741 tatttacttt ttttcttatc tagcatattc aagatattga ataaactgtt ttaagcaaat
    22801 ttaaatagta ggtattagat aaatattttg tttgacaatt tgaataagtg actagtattc
    22861 ctataattag tattatacag tattaatcat aggaatattt atgttaaggt gatttaattt
    22921 tcaataagta tatataaaga gtactctata aatgaatttt acaaagaaat ttaattaagt
    22981 aaatctatac taacaaatat gttagataga ttagaagttc aggggaatat ataaaaactt
    23041 gtgtgattgt aataaaagaa ttacactcat attaaacact ataaaagtag ataatgttat
    23101 taaaataact gaaaatgcaa taaataaaat agatacaata ttttatagta attttgaaat
    23161 tgaagacatg aaaaagttga aaaatattta gagcaaatat ttcctaatct caaaaatata
    23221 tattaaatag gagtgttgaa aatgtctaaa ataatagcat ttgtaggaag cccaagaaaa
    23281 aatggtaatg tagatacaat aattaatgaa ataattaaag gagcaaataa aaacaaggtt
    23341 gatgtaaaaa agtattactt aaatgatatg aatataaaag gttgtcaggg atgtttatat
    23401 tgtagaaaaa atcattcatg ttcactcaaa gatgatatga ttcaagtata tgaagatata
    23461 aaaaaagctg agtatgtaat tataggttca ccagtttata tatgtcaggt atcagctcaa
    23521 accaaattat tattagatag actttatcca cttacaacaa tagataaagg taaacatata
    23581 cctagattcg gaaataaaag aataattatg gtttatactc aagcagcacc tttaccaata
    23641 ttctttaaaa gatattttag atatacaagt aagcatctca aaggaatggg tttaaatcat
    23701 tataaaacta taattgctac taaagcattt gaaaaaaact caattgaaaa taaccctaaa
    23761 atattaaaaa aagcttataa ccttggattt aaaatatcaa aggatattaa tgtataaagt
    23821 ctactttaga tatttccaga ctcgatattt cctgaaagat ggtgaacatt ataataattc
    23881 accatctttt ttataattct atttgtaaat attctactta aaaagtatta tatatataaa
    23941 attagatgac aatattattt gataatagag tatatttttt aaaatctata aatatttcat
    24001 tatattattt tttataataa acattattct ataaaagtga cgtactattt tctcctgaat
    24061 atctgtagtt gtttttacat cacattcctc aataaatttt tttaatattt cgtttttatt
    24121 aaagataaaa aatgtgcatc ttcctttgta tagtgatatt tgatattttg attatcacaa
    24181 ctttttagaa gaatacacac tttattttaa atacactgct actatgttat tagaaaatgg
    24241 tgctagtata aaagatatcc aacatatact acatcacact aaaatttcaa caactatgga
    24301 tacatattca catataacta attttattct tctttcacag atttcctcat tttatcgaaa
    24361 cttcttgtac agacatacat tccataataa aatctacctt ttaatattat ttcacgattt
    24421 cgttatagac gcgtaaacaa acaataaaaa actgtgcatc tcccttgctt cattcatact
    24481 gacattttat ttataagact cttttgcgtc tccttttggt ttcatggacc aaaacactac
    24541 attcattaca atgacaatca gtaatacaac tgccatagcc acccaaaagc cgatattaag
    24601 accaaaccat tcggtagttc cgaaaagggt catccaaagt tctttccagt tcatcattgc
    24661 acctccttaa agtagttcgc cgaaatgacg gatataggct tttttcaaac ttgttgccaa
    24721 aatcatatac agcagaatac atggaatcag atatgcaaag tatgttgcag gcaatgcaac
    24781 aaatccaagc atagttccaa acacagtaaa cggaataatt gtcagaaccg taattcctgt
    24841 cattgttagc aaagtcaccg gagctgatgc acgactctga aggaaaggca gctttggagt
    24901 acgaatcatg tgaatgacca atgtctggct ccacatagat tccacgaacc atccagcttg
    24961 aaacattccg atatactgcg cctgaagcat tgccagctct gcaccgctga aatgggcagg
    25021 caaatcattg aataacacac cattcgatac gaacaatggg caaaatacaa agtacataaa
    25081 aatatatgtt gtaaaatcga agatagagct agttggtcca atccagatca taaaacttcc
    25141 aacactggaa gcgtcccatt tacgtggttt ggcaataaat tcctcatcca cattatccca
    25201 aggaattgcg gtacaggata aatcataaat taagtttaga attataagat gaacactcat
    25261 cattggtagg aagggtaaca gagcagatgc agcaagcact gaaaacatat tgccgaagtt
    25321 ggatgaagca gtcattttaa tgtatttaat catgttcgca tatgtctttc gtccttcaat
    25381 gataccctgt tccaaaacca tcaggtcttt ttccaataga ataatgtcag cagattcttt
    25441 tgccacatcc acagcggtat ctaccgaaat accaatatcg gcagctttca tagcagcagc
    25501 atcattaata ccgtcaccca tgaaaccgac cgtatgacca ttttcacgga gaacagaaac
    25561 cacacgaact ttctgatcgg gggttaactt cgcaaataca tctgtagaat ctgccactct
    25621 tgcaagctct gcatcgccca tttgttccaa atctgaaccg agaagcatat tgcgaacctc
    25681 tagtcctacc tgcttgcaga tagttcgagt cactttgtcg ttgtcacctg tcaaaatttt
    25741 ggtgataaca ccatggtctt tcagagcttt aatagcatct gcagtagatt cttttggagg
    25801 atcaaggaat gccagatatc caatcagtac catctcacac tcatctttaa caccaaatgc
    25861 gccgattggg gaaggattac tcttctgtgc aatcgctagc actcggaatc ccttatcgtt
    25921 aagattggcc actgtctcca aaattctgta acgaatgtca tcagtcagag gctgcacttc
    25981 tccattacac tctgcaaacg cacaaataga gagcatttct tccacagcac cttttgttac
    26041 catctgggtc ttaccacctt tatcttgtac cactgtagtc agacgacggc gtgtaaagtc
    26101 aaaaggaatc tcatctactt tcacatagtt ttcggacagg tctgtgagac gagaatctgt
    26161 ggcttcctct tcctcagttt tatggataat tgccaaatcc atcaggtttt tatagccagt
    26221 ctggaagtaa ctattgaggt aagcgtgacg cagtactcgc gtatcgtcct cgccatttac
    26281 attcagatgg tattccagca caaccttatc ctgagtcagc gtgccagtct tatcagtaca
    26341 aagaatatca atagcaccga agttctgaat ggaattgaga tttttaacga ttgtctgctt
    26401 cttgctcatg gaaacagcgc ctttcgcaag acaggttgtt acaatcatag gcagcatttc
    26461 cggtgtcaaa ccaacagcaa tagaaactcc gaataagaaa gcctccaacc aatcaccctt
    26521 ggtgatacca ttgacaaaga acaccagtgg aaccataatg agcataaaac ggatcaatac
    26581 ccaagaaacg gcgtttacac ccttggtaaa gcttgtttca accgcctctc cggcaactgc
    26641 ggacgccata gagccaaaca gagtatgatc gccaacacaa acaacaacag ctgttgcgct
    26701 accagaaatt acattactcc ccataaaagc aatgcttgtg taatcagtca cgctttcttt
    26761 ctgagcactt acattggggg ttttttcgat aggttcactc tcaccagtaa gacttgcttg
    26821 actgacaaac aaatccttcg catccaaaat acgaacatcc gccggaatca tatctccagc
    26881 agacagatgt acaatatctc ccaccaccaa atcatccata ggaatttctt ttttttcttg
    26941 attcctacga gtaactgtac aagtggtcgt aatcatagct aacaatttct ctgctgcatt
    27001 tccacttctg gattcctgta caaaacgaag tgtaccggaa atgaatacca ttgttaaaat
    27061 gattacaaca gtcaggtaat caaagtcctc tggcacactg ccaaacaggg aaaaatacgg
    27121 aaaaatcata tccgtaattg tggatactac agccagacaa aataaaatgg cggtaaatgg
    27181 attgataaat gcaccagcta gccgttttgc tagagatttc tttttttcat gagtgacttt
    27241 attggtacca tatttagcac gacttacggg tattgcatct acttccaatc cacgaggtgt
    27301 ggtatgaaat ttttttaaaa cttctttaat aggattggtt gccgcaaatt gaatgcggcg
    27361 gttctgttcg tcacggatga ctgttttttc tacagtctga cgaacagcca tacgattttc
    27421 ttttttgttc attgttctta cctccttgaa ttttcatagg agcaaggaat attatatgag
    27481 tgacacggaa tctccaaatt ctcatctaat attctctgca tttgtggact gacatcagag
    27541 tccatgtctt tcacctcaca atcttaaaaa atatctatgt gaaaccgcaa tgcggattat
    27601 tggttacgat agcggacact tttttcgata taccagacat caaagctggc aacaatcaac
    27661 catgcgatta ttgaaaatat aaaccagtgg tttgaaaatc ctggcaaaac tcctttcatt
    27721 aagaatataa ttccatttaa tgcaattatt cctccaacat tacgagaaag cgggacaata
    27781 ttaattttat ctttctcttc cttcggcata tttttccaca gggaaagatg acgatatcct
    27841 tttcccacgg ctaaccaaaa gcctgcaaaa gtaaataaaa ttccaaaaaa gatacatgta
    27901 aaatccatcg cttgttcctc ctttcaatgc ttaaacctgt ttcttagttt cgtcagcttc
    27961 ataagtttaa tgaggagcac aatcatagta acagcaagaa taaaccagat cataacactc
    28021 acctgatacc atatcttaaa gattgccatt ctttgttcag ataaattcca acccaaatag
    28081 ctacatagta ttgtaaatac agggtagaaa taaaaaagaa ttgcctgttt caaatctttg
    28141 atttctctcc tcactcacaa cacctccctt taactactaa caatatataa aaaatccaag
    28201 tagaatcata tggctaaagt cttgcgattt tcttgcgatt tggtaagaaa atagacggac
    28261 tgaaaccgaa aatggtttta gtccgtcttt gtcatatctg atcattaaat ttatatccaa
    28321 taccccagat agtcaaaatg tatgtgggag aatctggggc aggttcaatt ttttttcgca
    28381 acttccggat aaaagccata atgttgctgt tatccagaag ataatcttcc tcccatacgg
    28441 cacgataaat ctgttccttt gtaaaaactt cacctttgtt ctggacaaga aagtacaaaa
    28501 tatcaaattc ttttggagtc aagttgactt cagaaccttt tatcagtact tttctgcctc
    28561 ttggataaat ttcaagatcc cctgctagga ttctgtctga cagagtaccc actggacaat
    28621 cgctttcttc tgatgaccct aacaataacg aagatacctc tccgcgaatc atctcctgaa
    28681 tgccagaaag taaatccttc gcataatcac tgtctggtgg atctcttaat agtttttcta
    28741 atagccagat ttcaagagcc gaatccatcg gaatataact aatattcttt ttcatcatga
    28801 atgcctcctc ttaaatcaac tcttgatatt ttttcttata aaaatattta gctactgaat
    28861 tcatcagcat atagagaaat accaccagca gtaaaaatac gaaataccaa aggggcaatt
    28921 tcgtcagtcc aaacagcgat gcaccaccag caaaagtaag ataagtaaag ccaataatcc
    28981 ctactagagt tatagaaatg actggtgcag atgccctgct ctggaaaaaa ggaatcttgg
    29041 aagttcgcag aaaatgtaaa atcaaaacct gtgtccacat agattccaaa aaccatccag
    29101 tctgaaacag agctacatac tgaagtttca gagaaggatc tgtaagctgc agataggttg
    29161 cccctccaca tagcatcgga cataggaaat aatacaaaaa caggaaggta acaatatcaa
    29221 acagagaact gattggtccg aaagatagca taaactgtct tagtgttttg ccagaccagt
    29281 ctcttggaga tagcatttct tcctcatcta cattgtccca gggaagcaca atacacaacg
    29341 tatcatacag caaattcaaa agcagaatct gaattgaagt cataggtagg aacggtaaaa
    29401 aggcactggc acaaatgatg gaaaaaatat ttccaaagtt agagctagca gtgattttaa
    29461 tatatttcag catattggta aaagtttttc gcccctccat tacaccttgc tctaaaacat
    29521 tcaagtcctt ttgcaacaaa accacatcag cagcatcttt tgctgcatcc actgctgtat
    29581 ccacagagat tcccacattt gcttcattta gtgctggaat gtcgttgact ccatctccaa
    29641 gaaatcccac ggaatgacca ttatcctgca tagcagagac cagacgcacc ttatgtcccg
    29701 gagtaagctc tgcaaaaaca tgagtatgtt ccacagcctt tttaagttca cagtctgtca
    29761 tttcgtccag ttgtgtacta gttaagatac gctctgtaga aatacccacc cgacggcaaa
    29821 cagatacagc aatcgctgct tggtcccctg tcagaatctt aggaatcact tttaatcttt
    29881 tgagtgcagt tacagactcc tttgctgtct gctttggtgc atcaaagaag gatagatacc
    29941 caactagagt catgccccat tcatcatcag gagtaatttt cttttgtgct cctacatttt
    30001 ttcgtgccac cgcaataacc ttcattccat cctgtaacat ttcacctact acagaagata
    30061 cactctgtct cgcatcctgc cccatgggga gaagttttcc atgatattcc acataattgc
    30121 agcgtgaaaa gatatgttcg atatcccctt tcataataag ctgactattc ccattgctat
    30181 cctgtacaag tgtgctgaca aacttacgag catagtcaaa tggaatttca tcagcttttt
    30241 gaaattttgt cagaagattt gcataatggg cttcccgccc tggcatggta ttgcaggcaa
    30301 gaatggcatt atcaatggta ttgcagacac cagaatgata ggagctattc agataagcaa
    30361 gatcaagaac ctctgcattt tcatttccca agatatccat ataatattcc agcaggatac
    30421 tttcattggt aagagtcccc gttttatcca tacaaagcac atccatgctg ccaaagctct
    30481 gcatagcatt aatatttttg ataatagtct gctttttgct catagcaaga cttcctttgg
    30541 cgagacaggc tgtaataacc ataggaagca tttctggcac cagacctaca gcaactgaca
    30601 aggcaaaagc aaaggattcc atccattttc caccagtgat tcccagtaat ataaatacaa
    30661 tgggaactaa tatcgccatg aaacgaatca tcacccaggc gatagaatca gctccttttt
    30721 taaatgaatc tttatcatca gaatccggtt tggtaaatcc tccatacagg gtatctttac
    30781 ctactgccaa cacaattcct tccccttttc cactgatgac tgtggttgcc ataaaagcga
    30841 ggttttcaag ctgagtcagc gtctcctgtt ctccgtaact gagtttgcga cagctctttt
    30901 caaggatagc actctcacca gtgattgcag cctgagagat aaagagatct gtaatctttg
    30961 tcaatctgac atctgccgga acacaatcac ctgcggagaa tagtacaata tcccctacca
    31021 ctaattcttc gccaggaatc tctattaact ttccaccgcg cctcactgtg acgctttcat
    31081 gaactaggcg atcaagttga gcagcagcgc tctttgctcg tagctcctga atcagacgaa
    31141 ttacgccact aattagtatc atggaaaaga taataatggc agtagtagca tttctcgcaa
    31201 aattggatgc taagaaaaca tctgtaacaa gagaaacaat gcccagaaca aaaagaatca
    31261 catgaaatgg gttaataaat gctcgtctca atcgttgcat cgtcgtatca ttttttcgcc
    31321 cattgaagct gttcgctcca tatttctccc gcattgaacc aatttgctca atagatagac
    31381 catctggaga tgagccaatg tctcgataga tttctgatat ttcacagtaa gcgtattttt
    31441 taatacgact atcaaatagt gttgcttttg acacgaaaca tcccctcctt tataaatata
    31501 aataaagata tccacattat aacacagtgt tctaaaaatg ctatatttat attcttgctt
    31561 ttttcttgcg atttacttcg atatggcatt tttcagctcg atcaaatccg tatcgttaga
    31621 gtgaggtaaa tccttatcaa atttttcaat cattccttct aaatttggag cacggatgga
    31681 tgaagcaagc actttctcat agagctttcg cacagacata ggtatttcca ctttacacat
    31741 atgagtgcag acaaacgtct tcttggtttt caccttgacc atgtatcaaa tttaaattaa
    31801 ctacttagag aagtttctca tagtgatata tgtattatga gtgatagaat ggcaaaagtg
    31861 gcagtataga aaacgagtgt aaaagcaata caattagttt gtatggaata tctgaactac
    31921 ataattaacc actctgtagt ttataaaaca atacaatgcg taaattggaa cggaacagaa
    31981 aaaaccaata gtatttttaa taattccact tcactattga ttactcttat ctattattgc
    32041 tatttacaac aaaataaaac aacagaaatt ttaaatatgt tgactggcat aattcatatg
    32101 tatagaaagt ctacagttaa gatgcgattt ttctaatcca aatatattaa gaaaggaatt
    32161 ttacgaagcc attagtactt tgtttaagat gtctttcata aatataaaga ataatgttct
    32221 taacaaaggc gtgtaaattt atatagaaat gcatacttta aataattatc ccacaatatt
    32281 tcagttactg tctttatgtc ccacaagttc aaactacgac acctacattg cctttgtttg
    32341 attgtcaatg aatttcacag caccttaact ttcacattgt acccaacttc tcgatactcc
    32401 atacaatctc atctgtaact gtgtagctgg tcggtatatc cgttctaatg gtggtatcta
    32461 cattcaagtc ctgcaattcc tttgtcagat aaccgctgat tgtctacatc cttacttcga
    32521 tagcttcttt gctactattc caagtgtagt agaactttac aaagtttttg acgaagtttt
    32581 taatcccgtt ggtatcattc agttgtagcc tacataagat ttccatgtaa actctgctcc
    32641 ctctaaagaa gcgtttcctt gtgggttgta tttctgtgtt tccatgtcaa tcttgaaaag
    32701 ttcaatcaaa gtatctgtta cttttgtaca atacgctgtt tcgtcctcat ctttcgtgta
    32761 gctctcattg aatgtataac tgatataacc gtcattcatt actttttcaa caatcccgat
    32821 acgccctgtc gattctgtcc aatactattt atcagacgca tgaaccactg gtaatgacag
    32881 tagcaaaggc aagaacgccc atacacaatc gctttaatat ttttttcata attctaaata
    32941 ctcatttcat tttgtaattg ggtaaaaaaa tagacactta ttttgaagtg aacatcttgc
    33001 tttattttag tacttttctc ttaaaacgca atattcttca ttatctatta ttattttata
    33061 gcgagattga tttaataatc attgatgaag tagataatat tgtttggaga aatgaaagaa
    33121 gcactcctat agaaagagta cttttagtgt atattcaaga atttctctaa catgattata
    33181 acatgtctta tgttttagta tgataatttt cgttcgtttc gttcgtttta ttattacaat
    33241 gcatattata gttttactca tttatattaa taattacata tgtagataaa attatttata
    33301 tatatataat atttagcaac ttcatccaag tataatctat tttatgatat aattattata
    33361 aaagttcaaa tcattttcgt gttattaaag gaaatttatg caaaattgtt taagttatgg
    33421 agagttttat tatgttagat atgtttataa caatcgtttc ttctattata gaactatggg
    33481 catgcaagaa agtgtttgat tacacaagta aagtaaaaac tagtttaata aatttatatt
    33541 ttttaatttc cacttttatt attatttcta ctttctatac taatgttggt gctgataata
    33601 gaatattaat atgcattttt gtaatgtttg ttttttataa attaaattat gatgttaata
    33661 tatacaaatg tttgatagtt ttgttttctt attgggcaat actggtgtgc ataaatgcat
    33721 taagtatgat agtaatagtt tcgataaata acttgagttc tatgaatatt ttattaaatg
    33781 ataattttta tagatacgaa actatagttt taggaaatat agttctaatt gttttgttat
    33841 acatttataa attcatatct aatgatttgc aagtgactaa aagagaaatt tatatgtgta
    33901 taccaatagt agcaaatatg atatcatttt ttatatttta taaatatatc ttaaaacttc
    33961 tagatatttc ttccgctact aaattagata tcttaattat ggtgatatta ttaacatttt
    34021 ctaacatagc attgatttat agcctagtta agatattaaa aaataataaa aaatatattg
    34081 aattaactaa actacaggaa aaaataaatg ctgaaaataa atattatagt aatataaaaa
    34141 aatattatat taagacaaaa gaattaaacc atgatatgaa aaatcatctt atttgcatta
    34201 aggaaatgaa taaaaagaat attgatacca gtaattacat aaataacata gaaaaaaagc
    34261 ttgatgaata tagtactgta tttgatacag gaaatattac tttaaacatt atattatcag
    34321 aaaaaaaaga actttgtata gaaaaagaaa ttgattttac aattaatata aactttagtg
    34381 attgtaattt tattaaggaa gaagatacat gttctatatt tgcaaatgca ttagataatg
    34441 caatcgaagc ttgcgaaaaa atcaaaaatg atgataaaaa aatcaaattg cagggaatga
    34501 tagtaaataa attttttgta ataaaaatta ctaatacaaa atcaaatgat attttattaa
    34561 aaaagaatac ttttttaact acaaaagaag ataaagaatt tcatggatta ggaataaaaa
    34621 gtataaaaaa ttctttagaa aaatatggtg gtgcaatttc tataaatttc tctgaaaatt
    34681 tattttgttt aaatatgatg ataccaatta gaaaatcaca aaaagattca aatattgcat
    34741 atgagaatag ttaatatcca taatttacca ataaaattat ttaaggagaa aactaaatga
    34801 taaaatcttg tgctgataaa atagcttttt tgtttgtttt aaatcaagta atagaaaaag
    34861 atgatttaga aatctgttca tatgggttag aaattttact atcttccata ataaacactc
    34921 tatcttcatt aatgataggt ttaatattag gtagattgat ttattctata gtgttcttaa
    34981 tatctttttg tataataaga caattttcag gtggatatca tgcaaatagc aataaaaact
    35041 gtattctaat tttcaatagt atttttttta tatctatggt tttgggaata attttaaatg
    35101 attctaatcc tattccgtta tttttagtga tattgtctag ttttaacttt ctaagcattt
    35161 ttatttttgc tccagtatgt catgctaaca atccactaaa tgaaacaaaa tataaaaaaa
    35221 ataagttaat gtcaagaatt atatctataa ctttattctt gattattctt ctaggatgca
    35281 aatacttatc tttttacaat tatgttgtat acactttttt agctttactt tggataaatt
    35341 tattactaat tattcaaatc attataaata aaaaaataat ataaggagat attaacatga
    35401 aaaaaattct atatcatttt atgaaagcat gtggtgtatt agctatgttt gtagcatttt
    35461 tatctgcaaa cacaacttct ctgtggcatg tatatcaacc aaaaacacca gaaaaactaa
    35521 aaaaattcta aaaatcacca aaaagaaggg gctgtcgcat aagcaaatta aatttgttct
    35581 gtgacagctc tttttttact tattttaata ggtatatttt taattgtttt atattaagtt
    35641 tatattctaa gtaaaattat gcataacaaa taaaggtata aaaataccat ttttttagat
    35701 aatatttaat tataaacaat aaatttagaa tatttttttt aaatgatgaa gatatattcc
    35761 atgtttattt tttaccattt tattgtgtag tctagaaata ttatgagcta tcgctacaat
    35821 aatacattct gatagaacat tttctttacc tcagcttaaa aatcttctaa atttcatatt
    35881 ttttttactt gagcgaaagc tccttctgct tatatacttc tattcattct aggttcaaac
    35941 ccttccgggc ttataattct ctttaagttt tcttttcttt tttcataaaa taacttagat
    36001 acttgtaagt ttttagtcct attttcaaga ggaatcttac tattacttct cttaatacaa
    36061 ctgcttttat attgacaata acagcattct tcacaagtat aacaatttat ttcactttta
    36121 tatcctgttt ttgattttct attgattatt ttattagcaa aagtttttgc catttttaca
    36181 aatataataa tcattttttt catcataatc catattatca atacgcccaa tctcattttt
    36241 atattttcta gttttactaa tttcataatt tgcaggcttt atgaaagaca attgattatt
    36301 acgctctaaa aatgtatagt tttcctcacc ttcatagcca gaatcagcta ctattttagg
    36361 atatttaaac tttatatggt cttcaataga ttttaaaaat gatattaatg ttgtagtatc
    36421 agtaggttga tgccctgaac ttaccaaaac tatgtattct gaatctacac caaattgtat
    36481 gttatatgct gatttcaatt ggccattttt catatggtct tctttcattc tcataaaagt
    36541 tgcgtcatta tctgttttag aataactatt tcgttcaccc attatatgaa ggtctttagt
    36601 atattttttc aatctatcaa tataattatt taattgctct atagattttt gaatgataga
    36661 ttttttcttt cctttttcat gaacaaatac tatatttaat tcttttgata tttttcttag
    36721 tttctttaaa agttttttta gatgatagat tttgatttta tctttataga ttattttaat
    36781 accaaaatca atctcacatt tcaatatgaa gtcagatcta ttagcagatt actctatttt
    36841 tgtaccatca ataagcagag tatcctttga aatctcctta ttatatccaa taaagtttgt
    36901 aaactgtgca atcaaatttt tgcttacttg tgaaaaataa atactacgaa atcttgcaat
    36961 tgttgaatgg tctggggcgg aggctccgcc tagaagatac ataaagttaa tatctctttt
    37021 gcatgctttt tctatttctc ttgaagaata aatgcagttc atgtttgcat atattataat
    37081 tttcaaaagt tgtctagggg ttactttatt tcctctaatt cgagaataag tcttatataa
    37141 tttttctaaa ttcatctcct caataatttg acttaataac cttacagaat catcttttgg
    37201 aatcatgtaa tcaatattta gtggtaattt aaattgataa ttatcaccat aagtagtata
    37261 atcaatttgt atagtatttt gtttttgcat acaattatta tacaagaatc ccaagctctt
    37321 ttgaacttgg gattttttta tacaaaaaaa tggcgtagca ctattttcta gtgcgacagc
    37381 cccaactcta tattatttag aaattattac tgtaatttta ctatttgaac atgtacattc
    37441 aaaatacaag tctagaaatt agctttattt gtaagataaa taaaatcagt cccattatct
    37501 tctgtatgca aactaattaa gttattcttt tttaaatatt taattgcata tttttcctat
    37561 atacatagca tttataaaga aagttttata tacttaaact attatcttat ttaaagatat
    37621 taacaataaa aacctaaaac aagaattgta atacaagata aaatatttgt ctaaataata
    37681 ttgcttatca ctaagacaaa aactaaatta atataaaaat agaggtgatt agatataatg
    37741 aataattata attctataaa taacttacaa attggaaaaa catattctaa tgacgaaata
    37801 aaagaaatat ttaaatgttc tactcaaggt ggtatgataa aatcaaatac tacaaagact
    37861 ctagttatat tctctgatca tacaaaaagt atatatgatg atatttggta tgataatacg
    37921 ttaatataca ctggtatgag aaagaagggt gatcaggtat taaaaggtaa tcaaaatata
    37981 acactttatg agagcgaaac taatggaata aaagttcatt tatttgagac ttttgtctca
    38041 actaaacata tttataaagg atttgttaaa ctgtcaggta caccttttat aggtgagcaa
    38101 gaagatgttg atggaataaa tagaaaagta tggttatttc ctttgaaatt aataaataat
    38161 atacctatag aaaaaaatct attagagtat aataaaaatc ttaaatctaa aaaagctaga
    38221 aaaatgactc aattagaact aaaagataat ataaaaaata aaaccatcta caagaactgt
    38281 tatatcaaaa ccatatgtaa gagatgagct agtttctcaa tatgcaaaaa atagagcaaa
    38341 tgagatttgt gatctatgtg gttctaatgc tccctttaat gctctcatgg taacccatac
    38401 ttagaatatc accatattaa gtggctttct gatggtgacg aagatagttt atataatact
    38461 gttgcacttt gtcctaattg tcataaaaaa atgcatatat gtaatttaaa tgaagatata
    38521 cataagttat tagacaagat aaaaaattac gaaaagtaaa ttagttaaac aaatataata
    38581 aatttaaaaa ctaggatctg aatatttttc taattcagat atcctaccta ctgaatctat
    38641 ttgaaaagca tagaaatttt tcttatttac aagaattgct gaatctgaat catctatttt
    38701 ataagtaatc ccaaagaaat aacattcgtc caaatatgtt tgtgcaaaat taggtaaaga
    38761 atctgtattt tctattaaat atgcttcata tttatcgcct agaactttat tagctttctt
    38821 taaagctaaa tcatagttac taacttctgt tccatcttta ttgtaataat gccaactatc
    38881 tcctaattta atccacccat atttctttat tccatttgat acatctatac attgttgaat
    38941 tatactacta ttttctatac taatggcagt tattttggaa ctaccctcta atatgttctt
    39001 atcactattt gtatctacca aaataatagg atcattttta gctattgtag aaccaacaag
    39061 tgcatacact aaatctgttc cacttgctat ataaaattct tttgctccat tatagaactt
    39121 atttactatt ttcttattag tatcgtatct atctatacca cctaatctag ttgaattagt
    39181 atcatttact aagttatcac tcattgatga agtaccacct attgcataac tttctattcc
    39241 aggctaatat taaagatata caacatagat tagggcatgc taaaatatca acaactatgg
    39301 atacatattc acatgtaact aacaacatga gaaaccagac agtaaatatt tttgaaagca
    39361 ttgtagagta aatttgccac cgaaaaataa ttacggtggc aaaccggtgg caaacccacc
    39421 tttatagcat catatagata gctgaaagcc tcctattctc taacaagttt aactatagtc
    39481 tcgcaatgag gcgtattcgg aaacatatcc atacacttaa ccatcctaat ctcataacca
    39541 tatctcttaa aatcaaccaa atccacaacc aaagacttag gattgcaaga aatataaaca
    39601 atctcctttg caccaaatcc acaaatatcc ctaatagcat ctttatgaat acctggtcta
    39661 ggagggtcaa caataatcaa atcaggcttg tcctttaaat ccttaacaac cttagccaca
    39721 tccccagcaa taaactcaca attagtaagc ccattcaact tagcattctc attagcagca
    39781 acaacagcct cctcaactat ctcaatacca tacaccttct tagcagcacc agccataacc
    39841 tgtccaatag acccagttcc actatacaag tcaaatacaa ccttatcatt gtaatctcca
    39901 ataaaatccc tagcaatact ataaagaact tctgctcctt tagtattagt ctggaaaaat
    39961 gaaaatggag aaatcttaaa cttaagacct aaaatttctt cttgtatata atctcttcca
    40021 tataaaactc ttaactcatc acattggacc gcatctgcta aaccatcatt aatagtatga
    40081 agtaccccca ccaactcaga ttttaaatca atccctaaaa gcatatcttt aaactcattc
    40141 atatcaaaat cttcttgaga agaagttact atattaacca taatctcatt agtatgaatc
    40201 ccttttctaa ctacaagatg tctcaaatat cctttatgat tcattgttct atagtaagga
    40261 agcttttttt cattaaaaaa ctctacacta gaaactaata tctttgagaa gtcttcatca
    40321 accaacatac actcctcaac agtctgtata tctatatgtt ttcctttttt atgaagccct
    40381 aatgtcaaag gtccattttt tacttcatct ccaaaagtgt attccatctt atttctataa
    40441 tatttgtttt ctggacttcc ttctatccct aaaaattgaa atccaaataa atcttgcttt
    40501 aaaaataaat ccataacttg tttttctttt atttccaatt gtttttcata tggcacagac
    40561 agtaatgtgc atcctccaca ctctctaaag tgcttgcaag cttcttcagt ttcaagtggt
    40621 gagttttcta atagttctat catcttaact tcagctttct tacttctaac ttttttaact
    40681 ccagctctca ccttttgacc acttattcca cccttcatat ggataactct atctccaact
    40741 tggcttaaag atgtaccacc aaattccatc ttatctactt caaattctat aacatctttt
    40801 ttcttcacag acattcctcc agtttactat agtatcttta ttatctttct tcaatcaatt
    40861 ttatttcttc atctgttaac tctctatatt cacctaactc taaactttca tccaatttta
    40921 aattacccat agacaatctt tttaagtata ctactttttt gcctacactt tcaaacattc
    40981 tttttacttg gtgaaactta ccttcatgta ttgtaagctc tatctctgat tcatcatcac
    41041 tctttaagat atttagctga gatggcatag ttttatatcc atcatcaagt actacacctt
    41101 ctaaaaaagc ttctacatct tcttcagtaa ctactccatc aatttttgca taataagtct
    41161 taggcacatg cttcttagga gataaaactc tatgagaaag ctttccatca ttagttaaaa
    41221 ctaataatcc ctctgtgtct ttatctaatc ttccaacagg aaatggttca aaagctaagt
    41281 atgataaatc aattaaatct aagaccgttg ggtcatattt atctgtagtt gccgatacat
    41341 atccatctgg tttattcatc attaaatata tatactctct atatataact tcttctccat
    41401 taaacaatat ctcatcattt tcagtgtcta cttgagttcc tggatttgaa acttcacttc
    41461 catttactac tacagaccct tgcttacaat acttctttat ttcacttcta cttccatagc
    41521 ctaaatttga aagaatttta tctatacgtt gctttttagc cattaaaaat gctctccatt
    41581 ctcataatat ttttcttttt caaatactgt aaatgctaaa tccatacttt ctacatctaa
    41641 attagttctt atactatcag ttattattct tgctactgta tcttgtactt cttgtcccct
    41701 gtcaaaccaa gctatctcaa caaaaggata tacatctgct attttaccat ctcttattgc
    41761 aactgacttt atacattcta tttcaaagta gtctcttgga cattttacag cttcaactaa
    41821 atcatctatc attttttcac ttattttaca tatatcatcc tcattaattc ctcttatttt
    41881 tatctgtggc atagtttacc tcctttattt taaattttta gtgaattatc atccacttaa
    41941 ttaccttcga taacgtctga agtggtagct tcttggtcaa gataactatt gttatcagta
    42001 tctccaaact aataaggtag ttcctaccct tatagttagc attatatagc taagtttcct
    42061 gaattgttta tattctttat tattttattt aatcctattg tcttctattt aacattatac
    42121 ttgtaattta tagttattac aatttactat atactttttt tgatttaacg ttataatata
    42181 agtgatgggt aaattttaaa agttaatagg aggagtttaa aatggcatta attactacaa
    42241 aagagatgtt taaaaaagct tacgaaggtg gatttgctat aggtgcattt aacataagtg
    42301 acttagaaca attacaaggt gttttaaaag ctgctaaagc taaaaattct tatgttatga
    42361 tacaagcttc tatgtcagct gttaaatatg ctggacctca tacattagtt gaaatggtta
    42421 aggctgcttc tgatgaaata ggtgtagacg tagctcttca cttagaccat ggtccaaata
    42481 tggatgctat taaaacttgt attgatgctg gtttctcttc agttatgata gatggttctc
    42541 attttgactt tgaagaaaat gttagaataa ctaaagaagc tgttgaatat gcacactcta
    42601 aaggtgttgt tgttgaagca gaacttggtg ttctagctgg aacagaagat gatgttactt
    42661 ctgatgttca caagtatact caaccagctg aggcagttga gttcgttgaa agaacaggtg
    42721 ttgattcatt agcaatagct attggaactt ctcatggtgc tttcaaattc aaaggagaag
    42781 ctaaattaag attcgatata ctagaagaaa tccaaagcaa attaccaggt ttcccaatag
    42841 ttcttcatgg tgcatctgct gttgaccaaa acgctgttgc tacatgtaat gaatttggtg
    42901 gaaatatagc tggtgctaaa ggtgtacctg tagatatgtt aagaaaagca tcttctatgg
    42961 ctgtttgtaa aataaacatg gatactgact taagactagc tatgactgct gctatcagaa
    43021 aattcttagc tgaaaatcca aaagaatttg acccaagaaa atacattggt gctggtagag
    43081 atgctataca agctgtagtt gaaagcaaga tagatgatgt tttaggttct gctaactcta
    43141 taaactaata taacttttaa atatttataa aagaaaagag atgacttaaa gtaattaaat
    43201 ttatttttaa gccatctctt ttaagttgta tatatctttt tatataaaca aatatatgtt
    43261 atttttttac tgtattttta actatggtac catctctaaa ccctttagct atttcttcca
    43321 cattcatttt tacattatta gaagtatctg caaatgattt atttgtaagc aaacaaaatc
    43381 cacctaaacc aatcagtacc gttaatcata aagccataaa ctattttttt atgattatta
    43441 tatgcttttt tgttattttc taaataatac cataaaaatg tttatgtgct aatacaaaaa
    43501 cacttttagc gataatactc cttactgtga ttggtaagtt ataaatgtgt tattcaatct
    43561 agtagattct tactttttta gaagactgga acaaatcata tgagtacaca tctatagtgt
    43621 ttctaccaaa aaacaaaaaa atatcactgg aatcaaaacc tccagcaata tttaataata
    43681 aaaaatatat ttacataaat ctatgtacat tttcctaata aagtatattt catcaattct
    43741 aattacttta ccaaactaac aactatacat gaatatgtcc actctttatc tttctatgga
    43801 tggtagaagg atatatacct ataacttcag cagcctttgt tattgaacca tacttattta
    43861 tagccttact tatcattatt tggtccacta ttttatatgc atcattaaga ttcataattc
    43921 catttaccac tattggtgat aaatcatctg tttcattatc aatcatatct aaatttataa
    43981 gcatattaaa ttcatcttct ccaattatat ttttagctga taatactacg aatctttcaa
    44041 taatgttttt taactctctt atgtttcctg gccaagaata ttcttctagt aactcaataa
    44101 ccttaggtga aacttctact tctctattat acttttcatt gtaaagtttt aagaaataat
    44161 ttactagtgg tactatatct tcttttcttt ctctaagtgg tggtattttt actggaataa
    44221 cactcaatct atagtacaaa tcttgtctaa atttaagatt atttctaagg tcttcatgag
    44281 aaatattagt agcacttata tatctaacat ctatctttat aggcttacta ccacctattc
    44341 tagtaatagt attttcttgt ataactctaa gtaatttttt ttgcatctgc attggtaatt
    44401 cacctatctc atccaagaaa atagttcctc catttgcttc ttcaaaaagt ccctttttgc
    44461 cttttttctt agcaccagta aaagaacctt cttcatatcc aaaaaactct gactctaata
    44521 attcatttgg tatagctcca cagtttatag ctataaaagg tttgtctctt cttgaactat
    44581 acttatatat tgttcttgct attatttctt ttcctacacc tgattctcca tttataaata
    44641 tagaagaatc tgatgctgca gctctcttaa caactttttt tatattgtcc ataatcttac
    44701 tttgacttat atattctgtg tcttctgata tatcactata ttttatctga gattcaagct
    44761 tgataaccct tgaaatatct cttcctgtta gtactcctcc cttaagcttt cctttagaat
    44821 cccatcttgg aactgctgtg tatgcaataa gcttcccatc tgggtaaacg atatttctat
    44881 aaatcttttt cttcacttta agcatgttta atattattgg ttcttcaact aatccttgtc
    44941 ttacaaggtc tgttatattt ctaccaagta cctcagttct tttgaagggt aatatctcgt
    45001 cactgacagt attcatcttt tcaattaccc catctttgtt aaacacaaca acaacttcat
    45061 ctatatgctc tattatatct tcaattactt tatcagatat tagagacttc tcaaataaat
    45121 aaactacatt atttttatta ttattatctt tcatattgta tatatgtgca gtcatcctta
    45181 actctctgaa agctattttc tttttactat ctgtcagtat ttctgttttg tcaaaatttg
    45241 aatctaattc atttatattt ttaggctttt ttatatctag aaaactaaaa atactatcta
    45301 ttagatgatt acagtatatt atttcgcctg attctttaca taaaatggct ggattttcta
    45361 catgttctat aagccctatt aaattattat ccattaatat tcgcaccttt cattaagtaa
    45421 tttattgaac tacatacaaa atttattgtt tgcttacaat aaataccatc agcacatata
    45481 atcaactcct tataatattt gtcttttcaa gtagtttctt tcattaaaac gtaaccaaga
    45541 tataatttta atgattatag tttgttaaaa atttcatttt gcttttaatt gtattttatc
    45601 acatatttag taattatttg tctatttaat acaatttaat taaatttaag atttattgaa
    45661 aaaacaaaga taatccttac agaatatgac tcacaatttg taagcaatat acatataagg
    45721 attatctaga ttatcttgta ttataaaatt ttattcaaac agacttttta ataactgaca
    45781 aatacgcact agcaataact tatcaaaggg ttaataatta tgttactaac taataagact
    45841 tattcaatca gtaatattta tatagtttgt atctattaag cttttatagc ttctaataaa
    45901 tcatcaacgc tatctaattt ttctataagc attggaacta tttcatgtaa gtctccaact
    45961 actccatagt cagcgatttc taaaattgga gctgctgggt ttttgtttat agcaattatg
    46021 aaatctgatg attgcatacc tgctaaatgt tgtattgctc ctgatatacc acaagctata
    46081 tataggtttg gtttaacagt agttcctgtt tgacctactt ggtgagaatg gtctatccat
    46141 ccagcatcaa cagcagcacg agaagaacca actactccac ctaatttgtc agctaatttc
    46201 ttaagcattt caaatccttc tggtccacct aatcctagac cacctgatac tataacattt
    46261 gcatctgtaa gagatactaa atctttttta gttttaactg tttctaaaac agtagttctt
    46321 atatcatctt gagttatttt gtaatctaat gctataactt caccagttct tgtttcgtct
    46381 ttttcagctt tatccataac accaggtcta actgtagaca tttgaggtct atggtttgga
    46441 caaatgattg tagccattat gtttccacca aatgctggac gagtttgttt tatcttctta
    46501 tcttctgggt ctatttctaa tttagtacag tcagctgtta atccagttcc aactcttgaa
    46561 gctattctag gtgctaagtc tctacctata tgagttgctc cgaaaagcat tatttctggt
    46621 tttatttcat ctattgcatc ttttattact tttgtatatg catcagttgt atatttttct
    46681 aaaagagcgt catctgcaac ataaactttg tcagctccaa aagtgattaa ttctttagct
    46741 aatccatcaa catcttttcc taataatatt gcacaaagct ctgcatctac ttctttagct
    46801 aattttcttc cttctcctaa taattcgata actactggag ctatttttcc ttctctttgt
    46861 tctgcaaata tccatacgtt tttataagaa cttaaatctt ttatatcatt catagtttgt
    46921 actcctccaa cttatataat gtgcttttgt tttagaccga ttattatttt actagctatt
    46981 tcatcagctt taccttctaa gatttctcct tttcctcttg gttcaggagt aaatgatcta
    47041 aatactttag ttggtgatgc ttttaaacca acttcttctt tatttacatc taaatcatca
    47101 attgtccaaa cttttacatc atgtttatat gcttttacta ttttatcaac agacatgtat
    47161 ctaggtgtat ttaactcttt tactgctgtt aaaagtacag gtgtacttac ttttattaat
    47221 tcatatccat cttctaattg tctttgaact attatatctt ttccttctat tttaaaatct
    47281 tgtacatatg taacttgagg aatgtctaat ttctctgcaa tttgtggtcc aacttgtgca
    47341 gtatctccat ctattgcttg tcttcctgca aatattatgt catagtcacc tattttagat
    47401 attcctgctg caatagtatt tgatgtagcc caagtatcag ctcctccaaa tgctctatca
    47461 cttaataata ttgcatcatc agcacccata gctaaacact ctcttagcat aaagtctgct
    47521 tgaggaggtc ccattgttat aactgttata gttacatcat catactcatc tttaattttt
    47581 aaagcttcct ctaatgcatt tgcatcatct gggtttaata tacttggaac tccatctctt
    47641 ataagagtac ctgtttcttt atttattctt acttcgttag tatctggaac ttgttttacg
    47701 caaactaata ttttcaaagt ctatacctcc aatttcatta gattatttat tattttaata
    47761 cgtttgatga aattaccatt ttttgaactt ctgatgttcc ttcgtatatt gatacgattc
    47821 tagcatctct gtacattctt tcgatttcat aatcttttat aaatccatat ccaccgtgaa
    47881 gttgtaatgc tttataagca acttcatttg caatttctga tgcatagtat ttagccatag
    47941 cagattcttg agcaactctc attcctgcat ctctcttttg tgctgcatca taaactaatc
    48001 ctctagctgc acaaactttt gtttccatgt cagctatagt aaattgagta ttttggaatt
    48061 tagctatagg cttaccaaat tgaactcttt gttttgtata tttaacagct tcatctaaag
    48121 caccttgagc tattcctaaa gctaaggcag caacacctat tctaccaact tctagagtac
    48181 ccattgctat cttaaatcct tgaccttctt ttccaagtaa gttttctttt ggaactttaa
    48241 cgttttcaaa tattaagtca gaagtttcag ttcctcttat acccatctta tcttcatgag
    48301 ctcctgttga gaaaccatcc catttacttt ctactataaa cgctgatgtt cctctaagtc
    48361 ctttacttct atctgtaact gctattacta tagctacatc acagaatggt ccattagtta
    48421 tgaaagtttt tctaccattt aatatatagt ggtctccaac taattctgct gttgtttgtt
    48481 gtcctgcagc atcagaacca gctcctggct cagttaaacc aaatgctcct attaattcac
    48541 ctgttgctat accttttaag tatttttgtt tttgctcttc agtaccattg taaagtattg
    48601 gtaatgaagc aagagaagaa ccagctgtaa caaaagtagc tgttgaagca catcttctag
    48661 ctatttcttc cattactata gcgtaagaaa catatcctgc tcccccacca ccatactctt
    48721 ctgggatatt actgcttata aattttgcat cagctaattt tttgattaat tccttaggca
    48781 ttacacctgt tttatccatt tctgctggta aagtatctaa ttctttacta acaaaatctc
    48841 ttactgcttt tcttaaaagt tcttgttctt tgttatataa catagcttcc tccaattttc
    48901 atattttata gtaaatttat tttaatgaac ttacgctaaa ctcatcatct cagcaaaagt
    48961 ttgaatacga gttctggctt gttcattatt ctgagtttgt tggtcgattt caacatataa
    49021 agtaggtatt ccactatctt ctatatcttt tctaactaaa ggataatcgt attcttctgg
    49081 gtcacagaat ttcatcatac agaagataac accatctata tctttctttt taacttcatc
    49141 tactataagt gacccacgtt ttttcttagg gtcataagct aatgaacatc cttctatgtt
    49201 tgaccattgt cttgctaatc tttccaacgc atcatcacct gctggtacat ctgttctgaa
    49261 ttgtcttgtt tcttgtgcta agtcatcagc tacaactgat atattgttgt cttctaaaat
    49321 atctaatata tctttagaat cagctaatat acctgttaat aaaactttct ttccagaaca
    49381 gacttcttct ggcatagcat ttaattttgc tattaaatct ttcactagtt tagtgtgttc
    49441 ttcttttctc ataaagaatc cactcttaat tactaagctt cttattgatg gttttatagt
    49501 attagaatgt ttataagcta cttcaacaaa gtctctcata gtttttctat gttcattgta
    49561 aacttctata ctttcatgaa tttttgcttc ttctatttca tatccacata tttcttcaag
    49621 ctctcttttt acgcctttgt actcactgat taagtatttt acaccagctt caagttttct
    49681 attttgtggg tgtactaatg atatatattt tatatgaggt actgctgatt tccagttttg
    49741 tcctaaacaa attaatgtat cacacatacc tggtataata actccagata attcatcata
    49801 agcacctttt aatccatatt ctaaacatga ttgcattatt gaacatgcaa atgcagggaa
    49861 atattgttta gctaaatcta attctgtttg tcctccccat ataccaactg gaagcattcc
    49921 agctgcatgt ataatttctt ctgggcaata aactgggaaa caacctatag cttttttacc
    49981 agtttcactt ttatattttt ttacagccgc atttggattt tcaactactt ctttcatttt
    50041 agataaaata gcttccatta tatctcacct ctattaagtt tttttctttc ttccattact
    50101 tcaactaaac cttgaattct tgtttcaaat tgagcattag tgaaagctct agggtctgct
    50161 tggtcaccat caaatccagc atatggtaat ccagtttctt cagctgctct tctttgcatt
    50221 tcatattgta ttaaactcat aagtttacaa cttctgttca tatgataaaa tgctccatca
    50281 catttaccct ctattaaaga atcaactcta tattttgtca tacggtctag atttacattg
    50341 ttaaacatag tactatatgc tactgccatt ccatctaaat cattaacttc atattgtaat
    50401 gcccaagcat gtgggtaaac actacctgtc atgttaactc caaatttagc taatgttttc
    50461 atcttgtatc ctatatatgg ccaacaaggt ataccttcca tcattattct gtatttttct
    50521 tctcctctga aagaagattt accagttttc atgttgtcct ctaattcttc tataagtaac
    50581 ttaaatgctt ctgtagtctc ttttttacct ctagcacaaa ctattacagc catataagta
    50641 aataagtcaa atccattcat tggagaagga gaagaatctg ctggtaaact catagaatac
    50701 ttccatagtc ttccgttttc agctgatatt ttcattacct cttcaaattt cttagggtca
    50761 aatttctttc ctgatataat ttctagttgt tttatagctt cttcaaattg agctttaata
    50821 taatctattc ttgattgagt aacttcatct tcattattga aagttgtatc aatcattatt
    50881 aaaggtatat ctaattctct tgaaatattt tcataccatt ttataacttg gttacatata
    50941 ttgttacagc aaagtaggaa atctggagct ggcatatcca aagcttcaca tccaccattt
    51001 tctaaaagac caaaatttgt tcttgcatat gcacataggt caatagaata tcctttagat
    51061 tcagccattt cacataattc taaagaacct tttttagctg ctactccagc cgcttggttt
    51121 tctggatata atacgtttaa gtcaaatact tctgctaatt cttgaggaaa tactgatgtt
    51181 gaccaaccta caggtcttcc ttcttcttta gctttaaatg catttgcata ttgttcagct
    51241 aataaatcat taattactac tctagcttct tttttttcag acattttcat ccctcttttt
    51301 atatattttt cacttctttt tgtgattctt ttgcttcatc aaaagcatat aacgctgctc
    51361 ctaaagcacc agttaattga ggtatatcag gtacaataat ttctgtgttg atttctcttg
    51421 ccatagctct tacaatacca ctatttctag caactccacc aaccataact acatttcttt
    51481 gtactcctat tctttttact aggctagaaa ctctctttgc tactgaagta tgaatacctg
    51541 ctactatatc ttcaattttt gcattttcag ataaatgtga tataacctca gactctgcaa
    51601 atactgtaca tgtactgctt attgatactt cattttgaga attcatagat atacttccga
    51661 gttcagatac atcaacctct attatttttg ccattacatc taaaaatctt cctgtacctg
    51721 cagcacattt gtcattcata agaaagttta gtagtcttcc attattatct aactttaata
    51781 cctttgcatc ttgaccacct atgtcaataa tggttcttgt ctctggaatt atgaaattta
    51841 ctcccctagc atgacagctt aattcactta tttgcttatc agcatctgaa tagttcattc
    51901 ttccatatcc tgtaactaca acttttttaa tatcttctct tgcaagacct gtcttgccat
    51961 ataatttttc taaaactctt gatggtccag tagtcccagt accagaggat attgtttcag
    52021 aagctacaat atcttctcca ttctttaaga ttactccctt tgatgcagtt gaacctatat
    52081 ctaatcccat tgtgtacatc tttagcattc tccttttaaa aaatctagaa ttactaatta
    52141 atatcttaca actttactat ctttaaagtt atttattttc tcttcatcat agcctaaaga
    52201 ttttaatact tctacagtat gttgacctac ttttggtgct ggtgtatatt ctttaattcc
    52261 ttcatttcta aacataactg gagtattaac taagacacct gtatttccgc tatcatatgt
    52321 tttcttaaat aagaagtcat ttgcccaagc ttgttcgtca tctaataaat cttcacagct
    52381 ttgaattttt tcaaatggta aatctgcttc ttctaataaa gctgaccact cgtctagtgt
    52441 tttttctaac atagcttctc caactatttt aactaaatct tcaacatgat taaccattga
    52501 atctatgtta ttgtatctat catcttctaa tatatattct ctatttataa ccttacagaa
    52561 tttgcctaac cacttgttgt attgtattaa agctaattga atccatcttc catctttaca
    52621 tttatatgta gtcattaatg ggctgtttgg attttctctt gataaaggca tttcatttcc
    52681 gtattgtgct gttgttatca ttgttcccat tccatatata gctgtatgga aaagacttac
    52741 tgttactctc tcacctttac cagtttgacc ttttttatgt aatgctgcta aacttcctgc
    52801 cgctagtgct agacctgcat aatggtcacc aaatcctgct gctgtatttg ctggagatgt
    52861 tcctttttcc ataacagatt ggctaactcc tcctcttgcg aagtatgcag tatagtcaaa
    52921 tcctggttta tcttttaaag gtcctttttc accatatcct aatatttgag agaatattaa
    52981 tcctggatac ttatctttta tttggtcata agctataccc attttttcta atgcttgaac
    53041 tctaacatta gttacaaata tgtctgcttc tgataataat ttatgtaata tttctactcc
    53101 ttcttttgat tttacattaa tacttacacc ctttttattt ccattttcta attcaaacat
    53161 agggttttca tcatctgatg ctggagattt aaatgttcca cccataactc ttattccatc
    53221 accttctata ggttcaatct taataacctc tgcaccccag tcacctaaca tttttgcaca
    53281 acatggtgct gcaatgaaac ttgaaagttc tactacttta actccttcta aaagcataac
    53341 gttttcctcc ttaatagtat caattataaa atttcaatta aatcactcat aaaatacttt
    53401 ttctgatatt aactgtttga tgtcaaagtt cctaatctta tctaaaataa cttaaaaatt
    53461 attaaaatta ttttttattg ttttattgtc ttacacctat attgttaagc atttatcgtg
    53521 ccaactttat atttaatcaa aatatcgctt gatttgaatg ttttttaaca atatccaatc
    53581 aaataatctt tttcatatcg tggcatcttg caactatcca ttgcattttg ctattctttc
    53641 tatctctata aaagtttttt ttatatattt ttttatgaaa aagcttgaca tttcaaaaaa
    53701 agttttcatt gctaaactca aaaacacatg ttatcattgt aattaatcag caagttagtt
    53761 aactaatttc aaacttagat aattttttaa taatatttaa tctaaaaaat aacaatttct
    53821 ttgataaatt tttagagtaa ttattacatt aaataaaaaa ttactaaata tcaaaataac
    53881 acagggaaaa caatttcaaa gctaaatttt taaccttaaa aattttgtat aaaaaatata
    53941 gccttattta atacatatta ttatttaata catattattt ctaaatgaaa aattaccata
    54001 ataatttaat aattacagga gggtattgat atgaaaatac tagtatttgg agcacgcgat
    54061 tatgaagaac cagtaataaa aaaatggtct gaagaacata aggatgttca agtggatatt
    54121 tatcctgaaa acatgactga agaaaatata gttaaagcta aaggatatga tggtatatct
    54181 atacaacaaa ctaactatat agataatcct tatatttatg aaactttaaa agatgctggg
    54241 gttaaagtta tagcttcaag aactgcaggg gttgacatga tacattttga tttagttaat
    54301 gaaaatggac ttattgttac aaacgttcct tcttattcac ctaatgcaat agctgaatta
    54361 gctgttactc aagctatgaa ccttttaaga aagactcctc tagtaaagaa aaaagtctgt
    54421 gaaggtgatt accgttggat agctgaactt cttggaacag aagttagatc tattacagtt
    54481 ggtgttatag gtacaggaaa gataggtgct acttctgcaa aattattcaa aggcctagga
    54541 gctaatgtaa ttgcatttga ccaatatcca aatagtgatt taaacgatat attaacttat
    54601 aaagattctt tagaagacct tctaaaagaa gctgacctta taacattaca tactccttta
    54661 cttgaaggaa caaaacatat gataaataaa gatactctag ctataatgaa ggatggagct
    54721 tatatagtaa atactggtcg tggtggttta attaagacag aggacttaat agaagcacta
    54781 gaatcaggaa aaattagagc tgctgccctt gatacatttg aaactgaagg attattctta
    54841 aataaaaaaa tgaatccagg agaattaact gacccagaaa taaataaact tctttctatg
    54901 gaacaagtta tattcactca tcaccttggt ttcttcacta gtacagcgat tgaaaatata
    54961 gtttattcta gtttaagtag tgctgtagaa gttataaaaa caggaactgc tactaataga
    55021 gtaaattagt attttataaa tatatttttt cattaattag ctattatcta acaaaatagc
    55081 ctttaatttc ccaagtatga gagagtcagc tcaatatata ttgagtagac tctcttatat
    55141 tattttttat attaaactta tactcttctt attcatacca aattacattt atattaattt
    55201 attctaacta ctcttactct acatatattt tacccatttt tacttttcta attttttcta
    55261 attatataca tttgaatggg tacaatctgt attttacaaa aaaaacactt aacaaactat
    55321 gaaaattgta tgattaatat taatatattt ataagaaaac attacaatta tgttagctct
    55381 ggatttttag ggagggagta tattggaaaa aatgaataaa gttacttcta aaaaaactac
    55441 ctatattgtt acttcagcat tatttgcatc cataatatgt ctgacaatag catatatact
    55501 acatatccca gttggtggaa acaatggata tgtccatata ggagatgctt ttatttatct
    55561 agctgcaact attttgccaa caaactatgc tatagctgct tctgcaattg gtgctggtct
    55621 agctgattta tctacaggtg ctgctatctg ggtaatacca actataatca taaaaccaat
    55681 acttgtatta tttttcactt ctaaaagtga caagataata aataagagaa atatagttgc
    55741 ttcgattgta gcaggtataa taggattagt tttatacatg tttgctgaag gtataattat
    55801 tggaagtttt acaagtgcat ttgtaatgag tttacttggc ttattacagc caataggaag
    55861 ttttattgtt tttataatct taggtatggc acttgataaa cttgatttta aaaaacgtta
    55921 ttttaattaa gaatttaaat ttatggaggg aaaattatga atatcttata tacaattgaa
    55981 aatagtatct atgtgaatat aactaataca tgtccatgta gttgtgtttt ttgtataaga
    56041 aatgaaaaag atgaagttgc aaatagtggt agtttatggt tggagcatga accaagtgta
    56101 gacgaagtaa aagaagcctt caataaatac aatttagacg attatgatga aatcgtattt
    56161 tgtggatatg gcgaaccatt aatgagaata aatgaattga tagaagtagc aatgtttata
    56221 aaagaaaaaa gtagcataaa gataagaata aatacaaatg gtctaagtga tttaatacat
    56281 aacaaaaaaa cagctattat gttaaaagat gttatagatg cagtatcaat aagtcttaat
    56341 gctccaaata aagaagctta taatagagtt actcaaccaa agtttggaga aaaatcattt
    56401 gattatatgt tagattttgc aagagattgc aaaaaatata taaaagaagt ggctttttca
    56461 gtagtagatg aaatatctcc aaaagaaata gaagaatcta aacaactagc aaaaaaactt
    56521 gatataccat taagagttag acataagaac tagcaagtaa aattgtaaaa cattaataat
    56581 cacctgaaag gtgtttcagg tgattatttc tcttgtatta acatttcaca aaatagattt
    56641 cataccacac taaaaatgtg taaatcgtcc aaatctttct ccaattatta gaatttccac
    56701 taatgtagtc attaaaaatc tcattaatct catctatgtt aaagaattta tctgctatct
    56761 cactattgaa tttatctcgg atatcctgat tatatttgtc atcagccatc catatacgga
    56821 ttggtacaat aaatcctaat ttattcctaa aagcaatctc ttctggtaat acttttgatg
    56881 cagctttacg aaaggcaatt ttattctctc cacctttcac tttatattct gatggcattc
    56941 ttgatgcaat atcaaagatt cttgtatctg taaggggcat tctgacttcc aatccaactg
    57001 cagtactcat tttatctata ttaaaataaa tgtctccttc caaccatatt tgaatatcta
    57061 tatttgacat attagtaagt gtatccagtt cctctgtttc ttcataaatt ctttttgtca
    57121 gtttaatagg aagcacatca ggattgtatt tcttaagaat ttttcgcttc tcatcttcct
    57181 tcataatgtt cgtattccca atataaaatg tctttagatt ctccccataa cactttgcct
    57241 tatgatatac attatatcca ccaaagaact catccgctcc ttctccagag taacaaatat
    57301 ttgtgttctc agctgctgcc ttgcatccaa tagcaaaaac aatagcagat gcatctccag
    57361 ttggttgctc catatggtac attacataag gtactgacgc aaaatactct tcaggtgtaa
    57421 ttatatatct cgaattttta catccaagaa tatcagttgt ctgttgtgct aattttgatt
    57481 catcaaacca ctcttcctca taaccacatg agcctgtttt ttctatatct gacattgcca
    57541 atatataaga tgaatcaaca cctcctgata ggaataactc tgcagtttca tcctctgatt
    57601 ttatctctgg cataattttt tgaagtgttg tatgaatttc atctgtccat tcctcaatgg
    57661 acttgctgta gtcaggatga aattcaggtt tccaataacg ctcaatacat actgttttgt
    57721 tctgatagac aaggtaatgt cctggcataa gcttttttac tccacggaag aatgtatttt
    57781 cacctgctac atatgtaaaa gacatataca tctgtaacat ttcttcattt aactctttca
    57841 caaatcctgg ttgttccata agcttacgaa tagatgaact atagagaagc ttcccatttt
    57901 cagtcttata ataatagaaa ggttttactc caaactggtc tcttaggcaa aaaagcttct
    57961 tttccactgt atcccatagt gcaaaagcaa acattccatg catgtgattt gccatatcat
    58021 atccccaggt tttgtatgct tctactaaaa ttgctcgctc acgctcatct ctacctaaag
    58081 aagaatcgat tcctagctcc tcacagagaa ctttccaatt tctaatatgt ccattgtatt
    58141 ctaaaatttt tatcatacat gtatcttttc gtgttgaata cttttcttct aagtttatca
    58201 tatgtgtatc ctttcatatt aaaacattta attcttaaat ttattgattg tttttattta
    58261 tatttattca cttataatca ttgaaaatct acttttttca aagtaaactc ttttttaatt
    58321 agtgctaata tgctctttgt taaggtcacc aatatgatta ttaattatta tcagtgttat
    58381 aacattgaat tttttatttt tcataaatat tgccctcctt taaattatta gctaaatata
    58441 atatatctta tgttacttac atattcttta agaaatgctg aagattttat aaagttttct
    58501 gtagtataat taattaaaaa tacaattcta gttataaagc atattttcta ttaaacaaaa
    58561 aatagttaaa ataaattcat aataacataa acttatttta actatttgta tattttagtt
    58621 ataaatattg acttaaattt ttaacaggat acactcataa aataaacacg ataaacaata
    58681 aaataatata tcttagtttc tttatatact ttgtcttctt tcaattttct accatgtaga
    58741 cggttaagat aatattagta attcactcta ctgcttaact cgtgcgatat ggacaaccaa
    58801 gaaagctatt tcctcatttg ttaacttttt tccatatttc ttttctaaaa aatctctaac
    58861 ttttaatgca attgacattt cttttggatt tgaccttttc atttgattga ataataaatc
    58921 atctacacta cttaacatgc tatctgaaaa aaatctttcc acaaaaaatt ttatatgtgt
    58981 tataaatctc atataatgca tacttttttt atctaaggtt ctattcaaag aaaaaacaaa
    59041 aatattaatt atttctccaa ttactttggc atatttaatc gtatcatatg aatttccatc
    59101 tgaagccata gcgtttgcaa aatgaaaagc aatattggct gcttcttctt ctggtaattg
    59161 aatgcccaat ctctcttcta ccatgtaaat tgcaaccatt ccaaccttaa actcatttgg
    59221 ataataattt tttatttccc aaaatactcg atttgtaatt tttattcctt tacgcatcct
    59281 ttcaattgca aagttaaaat ggtctgctaa tattaagtat aagtttttat taaaagatga
    59341 gttcaataat ttttctgcct ctactattat ttcctgtgtt atctttaaaa tgtcgacaga
    59401 aatatcatcc attaattcta aaaattgttt tgattttgta ttttcaacag ggacaaacat
    59461 ttgattatca ttggaaccac aaatatattc tcctgttttt ttaccatatc caattccttt
    59521 ccctagcaaa ataaattcat tatcatttgc atcatgaact aaaacaacgc tcgagttcaa
    59581 aactttcttt attatgtagt tcattttatt tgctcacctt ctattggtca tttaaaatct
    59641 atactattat tttcaattac ttttttatac caataaaaac tatctttctt atatcgatta
    59701 tatgtcccct ttccataatc atcagcatcc acataaatat atccatagcg ttttgacatt
    59761 tgtttcgttg attcactgac caaatcgata caaccccatg aagtgtatcc ccaaagttca
    59821 acaccatctt caataatcgc atctaacata catttaaagt gttcttttaa ataatcaatt
    59881 ctatattggt catggacttt tttatcttca gttaaaatat ctttcgctcc taatccattt
    59941 tcaactataa ataaaggctt tctgtatcta tcatataatt caatcaaaga tatgcgtaga
    60001 ccaattgaat caatttgcca accccactca ctcatttcta aataaggatt ttttacagct
    60061 aataacgtat tccctgatgt aacatctaat ccagttgtat cggctgcttc acaagaagac
    60121 atatagtaag agaatgaaat aaaatctact ggatactttt tcataatttc atcatcctgt
    60181 tcttctttta ctatttgaat gttattattt ttaaaatatg acaataaata tactggatac
    60241 tcaccaaaaa cctgcgtatc actgtatgca taaatacttc tcattttttg ttgggctgcc
    60301 aaaacatctt ctggtctaca tgtatatgga taatatgtta attttgttaa catacaccct
    60361 acttttgaat ttggaataat ctcatggcaa atttttgttg caagagcact agctacaaat
    60421 tgatgatgca tagcttgaaa aataactccc tcaaagtttt tatccttaaa acggtctcga
    60481 accaaaccac cagtagtgta tggatggcga atcatagaat caacttcatt aaatgtaagc
    60541 caatacttca ctttgttttt atatctttca cagatagttt ctacatacct aacaaacata
    60601 ttgataactt gtcgtgaata ccatccatca tagtttaaaa cgatatttaa tggtggttca
    60661 taatgtgaca tagtaacaag tggttcaatt ccataactta ttaactcatc aaatacatca
    60721 tcataaaact gtaaaccttc ttcatttggt tctgtatcat ctccatttgg aaaaatacga
    60781 gaccaagcaa tactcattcg atatgtctta aatcccattt ctgccatcag agcaatatct
    60841 tctttatagt gatgataaaa atcactaccg tgacgttttg gataatttac ttcatcttca
    60901 ggatgtgcta atccttcttc tatgtctctt gtcgtaattt cattattgga tttatagtct
    60961 ttcacatcca catcaaagtg tgcttttgct acatctgata cagaccatcc tttactacct
    61021 aaattccaac caccttcaaa ttgattggca gctgtagctc ctccccaaag gaatccttct
    61081 ggaaattttc tcatacttat attcctccct ttacatcaaa caagatgctt ccttttgtta
    61141 cattgccata agactgattt aacactttat agtcataatc tgccccatta ctatttacaa
    61201 tcataacagt tgaatctaaa ttagcatgtg agattttgtc taaatcaaac tgaattaata
    61261 aatctccttc ttttacatta tcgcctgtct taacaaatgt tttaaatcca tctccattca
    61321 tacttacagt atttattcca atatgaatca aaatctcagc cccatttttt gttcttaaac
    61381 caattgcatg ttttgtttca aatagcatca caacttctga atcacaaggt gcgtataaat
    61441 ttccattggt cggtataatt gcaactcctt ctcccaaagt cttacttgca aataattcgt
    61501 cactaacttt acttaaatct atcacttttc cttctactgg agatactaat atatttactt
    61561 cttttccttc tattggctct tcttcaacaa cattttcaat tgatgactgt tctatatttg
    61621 tatcttcctt ccaaataatt agtgtaataa taaacgaacc taatattgca ataacaaaac
    61681 caatgcttgc aaaaattaaa ttatttccat tgtttgggtc aataaacatg ctcatactag
    61741 caagccctgg tccaacaatt acaaatcctt ttactgtaaa taaccctaaa aatataccag
    61801 aaatcgcact tgacaataca acacctagta ttgctctttt atgttgtaaa gtaataccgt
    61861 ataaagctgg ctctgtaatt cccatcaatg cagaaattcc tgcagataat gctgtttgtt
    61921 ttaatgtttc atcttttgtt cgcaatgcta ctgcaaaaca aacaccactt tcagaaatgt
    61981 tgtgagctaa tgaagctgtc atatataatg cttcataacc caactttcca attgtattaa
    62041 ttgcataagg tgttaatgct ttgtgcattc ctgttgcaac cataaatgga agaacagcag
    62101 caagtaatcc tacaactaag aatcccattt tgttatatag gaataaaata atggttgtaa
    62161 aaattgtccc aacattatat cctaaaggac ctaaaatagt tagagtaatt ggaacagtaa
    62221 ttgccaaaga catcatagga acaaagaaag ttcgaattgg ttttggtgaa tacttgttaa
    62281 aaattttctc cattattgac aagaaagaca cacataaaat agctgggaaa acctgtgcat
    62341 tataggcaat acttggaatc gtaaatccaa ataattcgac accttcactt aaagcagtcg
    62401 tcgttgctgg aagtaataag tatccaacag cagcaatagc tactaaacga ttacatttca
    62461 atacattggc agtagttaca gccaccatga gaggtaagaa atagaatgtt gcatctgaaa
    62521 tagcaattaa caatgtatat atagtagaat ctgattttaa aatattaaac attgctaata
    62581 acattaacag tgattttaga ataccagctc ctgcaatagc gaaaactaat ggttgaaaaa
    62641 tattaataat aaattctatg aatcttgttc ctaaatttat tttttcttca gtttttatag
    62701 cactatcatt tgtatctaaa gggcaaactt ttaaaatttc atcataaaca tcaacaacac
    62761 tatttccaat gacaacttga aattgtgccc tatcaactat actcataaca ccttgtactt
    62821 tttttaaagc atcttgattg actttacttc tatcaatcaa cttaaagcgt agtctagttg
    62881 aacagtgttc caaagctaga atattttttg agccaccaac ttgttcaata atgtcaatgg
    62941 cagttttttt ataatccatc ttgtaatctc cttctccata attttttatg aatggccatt
    63001 caagatgcaa aaaaggcaga acctatataa acaccttgaa aaatcaaagc aatatattcg
    63061 atcctgcctg cattaccagt aacatgtctt ctatttatac tattttgtac taccatatta
    63121 acatttgcct aaaagaattg tcaatacttt tttaaatttt ctgatactaa ctaatagcgc
    63181 ctttgtaatt catttttcat atcaattaaa gtaacagtag ccacccacca attagtatca
    63241 aaattgaacc tggtattttt tcttttatat tttctttgaa tataaaatga gcaagtatta
    63301 aagttattat catagatact tgagaaaatg gttcagctat actaagttct agattattta
    63361 aagcaattaa taacgctaaa taagagtatc cattaatagc accacttaaa attgaaagcc
    63421 cttttttatt attaaaaatc tcccaaatta ctttttgttt ctttttaaat gctaaaaata
    63481 taaataaatt taaacctaca aaaaaataca gtatagttga atataatata ggagatactt
    63541 gtacaaaaaa agctttgtcc aatactcttc ctactgactg taaaaatatg tacaaaaaca
    63601 ttaatctaca tggtaaattg ttaaaaatta cagagacatt ctttacaaag gagcttactt
    63661 tttttaatat aaacactcca ccaatcataa ttattattcc tgcaactttt gctaaactta
    63721 aaccttcacc taaaaatata actgataaaa gtagtaaaaa caatgaattt aaactgttta
    63781 ttggagtaac aagtgaaact tctccagttg ctaaagatgt cacatatgct actgagccaa
    63841 ttgaatatac taaactactt atataacatg gtattaaaaa agaccaatca cttactttat
    63901 ccattatact aaatggcagt aaacatactc ctcctataaa gaaaaataaa aatgatgaag
    63961 ctatattttt ataaatatct ccttcttcat cacccaataa tcttacaact actctttcaa
    64021 aagctaaaag cactactcta attaataatg caaaataaga taatatcatt tttgacctcg
    64081 cttaaaaatt aatctgactt attgttatat tgattgtaca aaactaccat ataggtaaat
    64141 cttttggatt ttttaatatt ttatgcttaa atacaggtat attaagtttt tcacctaact
    64201 tacggcattg ctccttataa gtacctttta acttatcatg aaaaactatg ccatcaatcc
    64261 catctgcaat actatttata cacttttcta gtttctcaag tcccgattca tcatcataca
    64321 ttccacttac aatccattga tttggcaata catgcccaat tgatatgtta aattctttat
    64381 tttttataat atctgagaaa gatttctcaa aatgtacccc tccaacacat aataaagtct
    64441 tcaaatgttc atcacaatca aatactctaa ttaatgattt tgccaatacc tgtattgcta
    64501 tactattatt aaaactatca ctactacttc ctatctcaat gtccaacata ggtacagaat
    64561 attctgtaat taatttagat tctccaccat atgttgttcc agaccagtgg gttgcttctg
    64621 ttaatgtagt aaattcatca agtgaatttt cattttttat atcttcaata gcattaatta
    64681 ggtttttaaa gtatcttgga tttgaattgc caaattctcc tgttggaaca tctccaattg
    64741 tatgagctgt taggatatgt tctggagcat tttctccctc atgccaattt acaactcctg
    64801 caaaatcata atctctgaaa tgtctattta aaattggaag ataatattca taatcatgac
    64861 ttattacata ttttgttttt acaaaatgaa ataagttatt gtttttatct ttaaactcta
    64921 atacaaaatt atcatcaata acaatatcag tttgatttaa atccattatt tcctcacaac
    64981 actttattac attactagct actgggtctt tctttaaatc actacaaaag aaaaaaactg
    65041 cttttttatt attcatccat aaatcacact cctataactt aaatataatc tgttctcata
    65101 cttaaaatta tttaaatatc actctagctc cattaaatta tttatacata atatactacc
    65161 atactcattt tagctatgcc tttgcctgag tttctatata tatgtgatac atcagcttta
    65221 aatcttatag aatttccact agatacaaca taatcttctc catttatttt aatggttacc
    65281 tcaccactaa aaacagttat aaactcttgt gttcctggaa gttcagcatt tgaatctaaa
    65341 tttccaccct cctctatttc aatcataaat atctcaaacc ttcttttcga atcaaatgga
    65401 aatattggat agcttatata ttttccatca tcttcaataa aatggtctac atcacttttt
    65461 tgaatcaatt ctatatcact ttcctgtctc tccatcaatg atgtaaatga gatttttagt
    65521 ccattagtta ttttcttcaa agtagatatg gtaggattta cctcacactt ttcaatttga
    65581 gacagcatac tcttacttac accactaagt tgtgcaatct tatctaagct aagatgtttt
    65641 tctttcctta tcttttttaa gttctcagca attatttcat ttaaactttg cataaattcc
    65701 tcctaatatg cttaataaaa acaagttatt ttgattattt aatagattta gtaacttaat
    65761 acaattttta tccattataa tgtacattat gtttaatata cattacttct ttaagaatgt
    65821 aaatagtttt ctgaaatttt gtaaaagtgg acaaataaaa agctagcaac ctatattttt
    65881 acaaggctac tagcttttat tatcataata tttcatttta actataaaac ttagatgcac
    65941 ctataagctg tctcttagaa acaatcttag ctaagtttgc taatgaagaa atttttatat
    66001 ctttaaaaga aactaaaaat acaaacttaa aatctgtaaa ttcttgattt atattgtata
    66061 tatcaaaata acatctcaaa ttatcaaata agtaattatc ttgtaaatct gcttctatct
    66121 catcagtagc atcttttaaa tacgctctta cgtcttcaaa taaaacactg aaataagatt
    66181 catctatttc ttcacctaat tcttctaata tttcttctat atctaaatcg ttcatatcaa
    66241 aagaatttcc tgtcaactga caatcaaata ctaatatatt ttcttgattt atagtatttg
    66301 atatatcttg tacatattca aaatctggac gtaattctaa aatgtctttt atttcactac
    66361 tctttacatg gatttttcct tttctatttt caatttttaa atctatcata tgctccccct
    66421 ttcaatctac aaatctttaa ataccttgtt ttataatctt ttcaatgtct atccaattat
    66481 taactctaac tatattttga tgtttaacat ctttattata gttagtatcc agaagtatta
    66541 ctttaacacc atcatcagct agttgcactg agtttaaagg gttatcttct ataaatatgt
    66601 cacaactcag ctctctcgcc ttttcaactt tataatcact tcctaataag taaacatcta
    66661 tatctgaaaa tccttgtctc gataaccaat ttttagttac atcagttaaa cactcatgtc
    66721 tagctgttac aaaagataaa ttatgtcctt tagataatgt gctaattacc tctgtagcac
    66781 cctctacaat ctttgcttca tcatatgaat gtatatactt attattaaac tctgcatata
    66841 catcccttat tcccgaacca tacaattctt cccaattatg tgttatacac tctgcttcag
    66901 tgatattttt attaaaaata tcatttaggt atggaagaaa atgataaggg cttgttattg
    66961 tcccatctat atcaatacat atattcaatt tgttcatttt tacctccatg taacatttat
    67021 tgatttgatt aatcaaacat tatagcacag ctttaattat aaatcaaaac tctagatatg
    67081 actataccta tataatacca aaaagcctgc atatttaagc aagcttttcg taaattttac
    67141 atttttaact aatatataag tttttctaag gttggttcta ctccaaattg tgatttcagt
    67201 tctttatatt cttttaatgc tttatcatta tttgttctag attttatagc tcttatcatt
    67261 aaattttttg gtgtgtcaag tggagatatg tattctacta cagaagtatc atatccattg
    67321 ccctccaata acaatgttct taaaccatca gttattaagt ctgcaaatct agctttaaat
    67381 acaccatgtt ttaatattgg ttccatagct tcatatctat attgacccaa taactcctta
    67441 tgacaacatg gcactactac tatagcttca gattttgctc taattcctaa acctattgcc
    67501 atatctgtag ctgtatcgca agcatgtaga cttattacaa ggtcaacatc cctattaggt
    67561 gtataattag tcaaatcctc ttttataaat gacatatttt tataacctaa atttttagcc
    67621 atatttcttg atgcttctat aactacatct gaataatcta tacctataaa ataacaattt
    67681 ttcttcaata cctcttttat ataaaagttt aagacaaagc ttaaataaga ttttccacaa
    67741 gcacaatcca agatagttat acagtcctta tcctttattt cttttaagat attatctatc
    67801 aattcaacaa aatggtctat ctgattgtat tttcttattt tatcattttt tatcttacca
    67861 tcttttgtaa gcactccaat ttcttttaaa agtgcatttg cctgtcctac ttttacataa
    67921 taatctctgt tttttatttg agatgctgta aattcatcta ttttaggtac ttcttcctta
    67981 ttatctaaat attttacatt taccttctta ttgtctcctt caattaaaac aatagttcct
    68041 cgctcaacat atttaaacac taatccatca taattttctg cctctttaga aatattctta
    68101 agcaattcat taaatgtata taaatctgat tttcctttaa aattaaattt atatttatta
    68161 tcttcctcta ttgcaattcc tttaaactct tttcttccag atttaaaaat tacctctaac
    68221 tcaataaaaa aatccctgtt atcaagattt ctttgagtaa tccccataaa aaacatattt
    68281 agttttccta tactctgctt attcattgta atctcccttt taacttatat ccttaaatct
    68341 tattaattga tactatttgt ttctgtgtta tttatttctt cttttaaatc attcaatcta
    68401 tttttaaaac tttctatctg cttatctgat aaatcaagat attctgttat cttccctata
    68461 tacttagggc ttttagtatt tattaatttc aaagcacttt ccatagattt ttctctaagt
    68521 tcatatgctt tctttacatc atctctagca ttactcaatg tttctgtata cttctcctta
    68581 gaaagttctg gaatctgcat attttcatat tcttttacaa cttctttaca cttatttctt
    68641 gcatttgtaa catctttttt tatactagat aatttagtta tattttttgc gatatcctta
    68701 gtgtaaggta tacattctct cattggaact aaagctgctc tttctatatt ataaatttct
    68761 ttcttaaaaa ttcctatact ttccatatct atttttttta tatcttcact atttttttct
    68821 ttacttgtat atttattatt ttcttttgta gtatcttctt gtttctctga tttattattc
    68881 actgaaacat tactatcaga gttattcttt tcttttatgt tattacttcc ttcttcgttg
    68941 ctttctttat tttgtatatt tttattttgt ttgttgttta aatttttatt atttgatatc
    69001 tcttcattct ttttcttatc ctgttttaaa tcagtacttt ctttttcctt aaagtttgat
    69061 acatactttt cgtcatatgt ctcatcagaa atataattgt gataatacat agattctttt
    69121 attttattaa gtccactcat ataaatatta cttatcatta ttgttgtagc caatactaca
    69181 taaatactac tatagataca agacctctta aaattcttgt aatttctgaa tatcactact
    69241 aaaggaataa gatataaaaa tataaaaact aatatccacc tcataagtcg tgtctccttt
    69301 ctcaaaaccg aaatccctca aatatttatt tttaatcatg tatcttatag tatttaccaa
    69361 tttatgtttt ttaatcgtga acttttatta aattaaattc tgtatagtca caagatgcta
    69421 atgtatattc tactccattt cgaatccctt tcaatcccat tttaaaagat tctttaccat
    69481 gcaagtgacc ataaatcacc ttttcaacat tatattcttc aaataacttt gtaaataaag
    69541 attcttctaa tttatcattt gtaggaggat aatgagtaat cacaattatt tttgagtgac
    69601 cacttttacg agcagattct aatgataacc taagtctatg ttcttctctt ttataaactt
    69661 tttcatcagt ctcatcaaac ttaacatcat taggacatat ccagccccta cctccacaaa
    69721 ttgcataatc tttatattca taaaaatttg tctgaataaa acgcatattt tcatataact
    69781 tatttaaact tgtaacggtt gtccaccagt aatcatgatt tccttttata agtattttct
    69841 gacctggaag tttgcttatt atatctaaat cttttttagc ttctgataaa ttaattcccc
    69901 aagatgtgtc tcctaatact aagaccatat cttcttcctt aacaacttct ttccaattat
    69961 ctataatctt cttttcatga ccatcccaat tacttccaaa gatattcatt ggtttattga
    70021 ctgatgttga aaaatgtaaa tcacctatag catacaaact cataatatca ttcctttctt
    70081 gattacaata aataggctgt ctctttttag aaattatttt ccattaagag gcagccccat
    70141 taatatttag caacttttct acaagtagtt tttactgaac tactttatca tctaccttag
    70201 tatccttata ttgctctagt aatatatcta tttcttgttt taattccaaa atttcagtta
    70261 tatttttatc tgtttcagtt ctatcaagtt ttctttgata ctgcatagct ttatgtgtat
    70321 cacccaagtc atataactct tgtattctat ttagagtatc tctaatagct atagacttca
    70381 tttggtacat agcctgagct ttcattatat cttctcttat ttcactcatt tcttggtcta
    70441 aaagaaaggc agcatcagat gctcttctaa gtctttcagc aagagtctca ggtatgtaat
    70501 ggtcatattt atattttaat gaatgttcta ttgtagccca gaaattcatt gcaagagttc
    70561 ttatttgtat ttcacatata atttcctttg aacctgcaat ggagtttata gggtatttta
    70621 ttataacatg atagcttcta taaccactat ctttgtaatt tgtaatataa tctttttctc
    70681 ctattatagt catatcattt cttactttta tcaaatcaac tatagcatat atatcctcaa
    70741 caaactggca cattattctt ataccagcaa tatcatcaat ttcagtttct atatcttttg
    70801 catttatcct ttttaactta gatattatgg aagatatttt ttttgttctg cctgtgacaa
    70861 actctatggg agaatattca ccttttgcta aatattcttt tcttatattt ttaaatttta
    70921 ttttcaattc ctctactgca tgttcataag gtgctagtat ctcattccat ttttcgtatt
    70981 ccatattgct caccctttat ttgtttttta tgaccttctt tattttatca taatttattt
    71041 tgtttttgta tagtaaagca attctccatt ttccaatata taccctattt cttctaaatc
    71101 aactaagtaa cttatgacag atactaacga agatttaaaa aaatgatact ctttataatt
    71161 attgcttaaa ttattgttat ttataatgtt ttttaataaa atttctaaag atttcggttc
    71221 tacaagcaac tctcttattt gatgtaaata tttttttaaa gcattcaaat gtttttcgat
    71281 taatttataa gaatcttctt ttgatataac ttgcttgcca tgacctaaaa ctaagtattc
    71341 aaaatctata ttttttaatt tttctaatga atttatttgt tcttgtatat catatagaaa
    71401 caagaagtcg tattttgaaa gaatttcatc ccctatcaat aaatcgccaa caaaaatcac
    71461 attatccttc gtcaaaacag ctatactacc aggtgtatgc ccctgaaact caattatatc
    71521 aaatatttca ttatttaatt caatttttcc agcttttata gatttatcta tctttatatc
    71581 atccaacatt ttatttttta agatattatc cataaataca ttgctctttc caccaacaat
    71641 atactttgaa aataattctg gattttctat atataactta tcgtattcag atgacattat
    71701 acgcacatct ttatagtact ctttaaattg attacaagct ccataatggt catcatgacc
    71761 atgagtattt ataatatatc taacttgtat attattttca tctaacactt tatttactct
    71821 cctaggtctt gaaccacata accctgggtc tatcataagt gctgtgttat cttcaaatat
    71881 atatatgcct gtatttgtgc caccttttat aaaaaaggta tttcctttta cttttgtaag
    71941 attcaccttc ttcacctcat tttgacaata tttatgatac aatttattac ttgctaatat
    72001 aaaactatac aagaataatc ctttttattc tatctatagt tctttttctt atttcgggtt
    72061 ctttagatat ccttattttc acattatatg ctaaatttct ataaagtaat gactctataa
    72121 aatattcaac tatacctcta tccctaaagt ctatatctat acatccactt gaataaatat
    72181 ttgagtctaa tgtcataagc tcatcaaaaa agcttaatct cttagattta cttaaataat
    72241 ctttatttgg aataaatcta tcacaataat ctatcctgta atttactact tcatcattta
    72301 tttcaaatcc atattgcttt ttcattaact ctctatagtt attatttttc tcaataacat
    72361 tatctaaatt tttattataa tcctcttttt tccaatgtcc aaacatccta caatttaatg
    72421 gtctaacttc atatattaaa catctattat tattatcttt aaatggacat ggattctttt
    72481 ttgtatactc ctcaaaataa taatctaata ttttacttat acagcttttt tttaaatcaa
    72541 ctctatcttc aagataacaa aatatattca aaaactcaat taaatttata cctactgact
    72601 ccatacaaca atttccacat cccaaacaat ttcccactgg caaggattta tatacatcat
    72661 ttagtttctc aaagagctta tttttaatgg aataatctat acaatttaaa atatctttat
    72721 tttttatact agtcattatt attactcctt gttataatta ttaagttaat acaaacaatt
    72781 attataacat attttttaaa tttaatcgca tatggaggta ttttatgaat agatatacaa
    72841 aaataattaa catgatggga agttattaca caaaagactt tgaaaaagaa aaaaagaacg
    72901 taataaaagt tagagaagtt aaagaagata cagttagaaa atttttctta caaggtgact
    72961 gtgaggttct tgtagtattt gaggatactg gaaaagaaat acttattgat gacttttctc
    73021 ctgaagaaga tatcaaaaaa tatttaggag caaaattcat aaataaaaaa agataattat
    73081 caaaaataat tctaaaatta aaagttaata aatataaagt tataattcta tataattata
    73141 gttaaaagtt atcttttatt gcttttttag actttaagat agcttttttt ctattttttg
    73201 taaaatagtt ccataattca cattaataat tcacaaaatg atataatata acaaatagat
    73261 aaatttttaa atttctaaat acataattaa tattttgcga ggtgatttta tgcaaattta
    73321 ttttagagtt aaggctattg gcaaacgtaa acctatgcta aaacttgccc cttttgatgt
    73381 atctgacaac atcaactgcc taaaagaagc tatctctgaa attgtatcta aaaatgttct
    73441 tgaatataat gagaaaatcc cagaaaaatc aatagtaaac ttcttaacta atgaagaaat
    73501 tgaatctcaa gctaatattg gaagagttgg atttggctct atttacaatg agaataaaca
    73561 atctgtagaa aaggcaatag aagtagcgtt acaagcattt gaagatggaa tctacaaagt
    73621 gcttataaat gaagatgtta ttgaaaaact tgattctcct ataaatctga aaagtggaga
    73681 tatatttact tttataagac ttaccttgct tgctggaaga atgttttaaa ataaataact
    73741 tggaggtaca taaatgttag aacgtactag agtagaaaaa aatcctaaaa taattgaaaa
    73801 tttaaaaaac aattttacta aatcttcttc aaaacagtat tacgacttag caaaacctct
    73861 ttgggactgc atagaaaata gttcatacta ttatagagaa cctgaagaca aattcttaaa
    73921 tatgataaag aaatactaca attgccacta ctacgaaatt aaaaatatgg acgagctcct
    73981 ttctggacct ttaaaaaatg cattagaatt aatatttact tctgaacaag tagaggaact
    74041 ttgccaatta attaaaagaa agatggatta tacatattca ggaggatatt atcgtaaagg
    74101 atatcgctca aataaacttg tggattattt tagaggcatt ataaggttta tttccagtta
    74161 tgttgatttg atttattatg atttttcagt tatagattat cttactcttc caaataaagt
    74221 cttgtactat gactctataa tgagtgataa aatagcacta gaaatagaca aaggaaatca
    74281 agaagtaata agtgccttag aagaagtaat atttggagaa aatcaaactg ctctacttac
    74341 aagacaaatg ataattggta tcatgaagag tcatagtgat aaatgctatg aaatgatttc
    74401 taaacttctt ttggcagcta aacaacaaga gggacttaga cagcaaattg tagaaagttt
    74461 agatgagggt acaatttctg catcaatata catgttaaaa actattttgg acaataattt
    74521 agagcgattt agttctgtta taagagcctt ggatacatgg acaggacttg gtttttcaga
    74581 ccaaaaacct ggaataatac gtaaatgttt agaactttca tataaatcat tgactgatga
    74641 aaagttccgt atagaatcaa ttaatagcaa tgataatctt gaagtttatt ttgccttatg
    74701 ggctactgca acttacaaca tatatgactc ttactctctt attgaaaact tactttcttg
    74761 tcaggaaaaa tataaaaaac ttgtagctct ttacttttta tcgcatacag aaagtacata
    74821 ttttaaacat tctatagcat ctaaaaacat taagggtgat gatttagaga tactagcatg
    74881 ggtaattaca aatttctatg tagaaggttc tgttggctac tactatagtt ggcaaaacag
    74941 agaaactagt tttgacctgt caaacactcc tattgacaaa gactttaatg ctagaaaaga
    75001 acaatttgaa agtttaaagc atactttaga aaatttaaat tcaaagacaa aatcattttc
    75061 aggaagtgta tttccatgga cttggattga aatttcttct catgaaatac ttaagtgtat
    75121 gatgacttta acagcatacg atatgaatgc tcaatttata gatgttctta tggaaaattg
    75181 tcatcttatg agttcagatt taagagcttc acttatagta aattttgtaa atgaaccaaa
    75241 gacagataga caacgtgaat ttttattgga atgtttaagt gataagagtg tttcaaatag
    75301 agaaatagta ttgactctac ttagaaaact tgaactaaca gacatggagt tggataagat
    75361 aaccaatcta ttatctttaa agacaagctc tattagacaa acagtaataa aaattttact
    75421 tgaacaagat gattcaaaat tggagaatat tgcttcttca ctgataaaat cttcaaattc
    75481 tcaaaaatgc cttggaggtc ttgaaattgt aaacttatta aaagacaata ctgatagaaa
    75541 agaactatat aaaaagctta ttttactgat aaaagatatt gataaatcta aaaagaatac
    75601 atctcaagtt caaatactaa ttgataattt actaggtaaa gcaaaaaatg attattgcaa
    75661 agaaaatggt tttggaatat ataacccaga aaataaggtt caaattccag aacaatttga
    75721 ttttaaagat aattctccta gtttatcaaa acttgataaa attatttcaa atacaagttt
    75781 atctactaat gaggattctg tttctgtagc aacaaaaaaa gaagcaaaaa aaattctcga
    75841 tacagatata aataaaataa taaaagttta tgaaaaattt gatgagctta ttactgaaaa
    75901 tgcagattat gaatatgaag ttgaaagatg gtcaggtaat gtagacaaag tacttttagg
    75961 ctattctact tataatttga ctcctattaa atataaagtt tctaatgata ctctagataa
    76021 ttatccattg gcagaacttt ggagagaaac tagtaaaaaa cttaacttag actacaaatt
    76081 aatacttgat atattatttt atagtataag tacatgcgga tataatgaaa tagaaaaaag
    76141 ttggttttca tctatatatt caaatgtcct tgactctaaa aaacaaaata aaatatctac
    76201 aaaacttgaa aaattaaaat tcaatggact tacaagaaag cttctaagag ttttactaaa
    76261 tgagttcgac cataaagaaa tatttaacta ttgtttggaa gtatactata aacttagaaa
    76321 cttattaact atagaacaat gtaaaaagca aagagttgag tttactaaaa attattatag
    76381 acaaaatgaa tactgccctg ctttaaatgc ccctatttta aattattggc ttgataaagc
    76441 acattcattt atttatgatg atatttcttt tactaagttt ttctacacta cattttcaaa
    76501 ttatcagttg ctagaatata aatttccttt ttatactagc ataaatgtat ttgctcgtgc
    76561 acatgaatta ggattaatga ctaaagagca agttaataga gaaatgataa gtggatacaa
    76621 cgcaacaaat ataataagaa cgttaacaaa tcctagatgg gctggtgaca cattagaaaa
    76681 atatccttgg cttaaagata acttaaaaac cgttacaaac cgaattatag aaattgaatc
    76741 acgtagaggt gatatgccaa cagaagtgtc tcatctagct aataatatac aatactttga
    76801 aggtataaat tattttgtaa atatcttagt tgctcttggt aaagaaactt tccagagagg
    76861 atattcatat ggtagcaatt attcaaaaaa agatgtttta agttctctac ttaaaaattg
    76921 ctatcctaca aaagaagatg attcaaaaaa attaaaaagt ttacttaaaa ataccgacat
    76981 tactgagtta agattgatag aatctgctat gtatgcacct caatgggtaa acataattga
    77041 aaaatattta aactggaagg gtctgaaaag tacaatttgg tacttccacg cacatataaa
    77101 tgaaggattc tctgcacaaa aagaatcaga ggttgctcta ttctctccta tatcaccaca
    77161 gagtttcatg gatggagcat ttgatgtaga ttggttttta gattcatata aaactattgg
    77221 ggaagaaaga ttcaatatac tttacaaatc agctaaatat ataactagtg gcggaaattc
    77281 tcatagacga gcacaactct atgctgatgc tacacttgga aaacttgata aagatatgct
    77341 gatgaaagaa attgaaacaa atagaaatca agataaattg agaagtttct ctttacttcc
    77401 tatgaaaaaa ggagacctta aagaagcaac tttccgttat gaatttattc aaaagtttgc
    77461 caaagaaagc aaacaatttg gtgctcaacg tcgtgaaagc gaatcaaaag cttgtgcaat
    77521 agcaatggaa aacttagcta gaagtgctgg ttttgaagat attaatcgta tgatgtgggc
    77581 tcttgaaaca gaaaaattaa atgaagttgc ttatatattc aaaccaaaaa atattgatag
    77641 aacttcactt tggatagatg ttgatgaaaa aggaaaaaca tctataaagg ttcaaaaagg
    77701 tgataaggct ttaaaaagtg taccaaaagc tattgctaaa catccatatg tacttgaact
    77761 taaatctgtt caaaaagatt taaagagtca gtattctcgt gcaaaacaga gtttagagca
    77821 agctatgaaa aatgaaatag tatttacagt taaagaaatt gccaatatct ataaaaatcc
    77881 agttatctgc cctttgatta aaaatctagt atgggtatgt gatgataata ttggatatgt
    77941 ttataatgat aagtctaagt tctttatttg caatatagaa ggtgaaattt ataagttgac
    78001 agcgaaaaat aaattaaaac ttgcgcatcc agttcatttg tttgagtctg gtaagtggag
    78061 tgagttccaa catgatttat ttagtaagca aattgttcaa ccatttaagc aagtattccg
    78121 tgaatattat agaataaaca gtgatgaatt atctgaaaaa actatatctc gtagatacgc
    78181 tggtcaccaa gtccagccaa agaaaactgt agcacttctt agaaatcagc tttggactgt
    78241 cgattatgaa gagggattac agaaagtatt ttataaagaa aatatagtgg caaagatgtt
    78301 tgcacttgca gattggtttt caccagcaga tatagagcct cctactattg aaacagtaga
    78361 attttttgat agaaaaactt ataaaagctt ggaattggct tctatacctc caattatatt
    78421 ctcagaagtt atgcgtgata tagaccttgt tgtaagtgtc gctcatgctg gtggtgttga
    78481 ccctgaaact agccattcta ctgtagagat gcgtatagca attgctaaag aacttttatt
    78541 attattaaaa gttaacaatg tcaattttga aggctctcat gctcttattg aaggtacttt
    78601 aggtgagtat tctgtgcata tgggttctgg tattgtacat aaaaaaggaa taggtgcttt
    78661 gaatatactt cctgtacatt ctcaaagtag aggtaagata ttccttccat tcgctgatga
    78721 agatcctaaa actgctgaga ttatgtctaa gatactatta cttgctgaag atagtaagat
    78781 taaagaccct agtatcttaa gtaatttata agtataaaaa ctatccctaa aatatattgg
    78841 actttcttaa aaaaattaga aagtccaata tatactatac tgtaatttat ataaattaaa
    78901 tcataattac aaataatttt tatatacact tctcttatac attatcttta tggtacttat
    78961 tatgtcacac aaaaagtatt tttcttctat tttcactaga atcttttaac cctataaaat
    79021 ctatataaaa agtctttttc tagagatttg tttaatatgg cattttcttg aaaatttata
    79081 aaccttatct ctaatgaaga tttatttata ggtataacct tatgtataaa tcttagattt
    79141 acaaggtata taaaaagtta taaagctaga tctttagcga ttgctgtgag tataattctt
    79201 gctacatcac tcgttgttgg tattggtact ctatcaagaa gtgctcagca agcagatgta
    79261 gatagattga aaagagagct tggaactgac catgtatact ttaaaaatat aaagaaaaat
    79321 caattaaagt ccataaaatc tagcaaagat attaaaaatc tgggtataac atcttactat
    79381 acgtctacag atgttaatga aaaattacct ataaacatac tatatgcaaa taaaaattat
    79441 ttgactagtc attctaaact tataaaaggt cgatttccaa aagctagcaa tgaggtggta
    79501 gtcgagaaat ggattttaaa tagtatgggc ttaaaaccag agataaatca aaaccttact
    79561 tttaaattat atcaaaaaga aaatccagaa acttttaaag ttgttggaat ccttgaagat
    79621 agatttatag agaaacaaaa gggacaatgt gaaatttttt ctaatctcaa tgaatcaaaa
    79681 ctgaatgatt ttacaactta tattgaattt aatgaaggca gtgatataaa tacaaacata
    79741 gacaatataa taaaaaatgc tatgttagat gagaaaagta taggaagaaa ctcaatgctt
    79801 atagaatcta ctatgaaaaa cggtacttta gataatgcaa gtaaatacgt tgcaattgct
    79861 atgagtctat ttgctggtat tgtaatatat agtatctatg ttatatcaat ataccaaaga
    79921 gtacaggaat atggtgtctt aagagctatt ggttccacta actttaggat tttcaaactt
    79981 atgctttatg aacttttcat acttgctcta atagcaatgc ctataggtat atgtataggt
    80041 atggggggtg cacaaatatt taataggtct gtaggaaata ttcaatttga aggaaatata
    80101 aatgttacac cttttgttat tccagataaa ataatcctct tatcaattgc atgtacaata
    80161 ctaataatac taattataag tttctttaca tacttaaaaa taagaagaat ttctcctatt
    80221 gatgctatca gaaaaacttt tggtgctgat aaaaatgtaa ccacagttaa ttatttaata
    80281 tcaaaattaa ctttaaatat gtcagtaaca aaatctatat ctgcgaaaaa catctttaga
    80341 aataaaaagg ggttcattat aattgtatta tctatgagta taggaggtat aatcgtcata
    80401 aaagacaatt ataaatattc ttttttagat gtgcaaaaca aatccactca agagcaaaca
    80461 tatatgaatg cagattttat tctatcaaat gtttatctca atgaaattgg tagcaatact
    80521 tcttttaaag atataaaagg gtttagtgat agtcagatag ataaaataaa aaatatagat
    80581 ggaattgaca aagtcaaaac tgctagtatc ttaaacacaa gaatagaggt aaataaaata
    80641 aatagattag attactacga agctataaat tcaaatcctt attataaact aaatcctctg
    80701 ttcataaaaa ataagactac tggcaaatat acactaaagc aaaaactaaa aggttataat
    80761 gatgagatga taaagtcatt agaaaaatac ttagtaagtg gaaatataaa cttgaaagaa
    80821 atgaaaaaag aaaatttagc tattgtatat gtaccagaaa tttctaaaac acagaaatac
    80881 acaaagactt ttactcctgg tgaaggaaca ccagctatag atataaaagt aggtgatact
    80941 ataaaagtca aatatccaaa gggtggaatg gatacaggac tttatgaaag tctaaaagat
    81001 aattatgaat acttagaata tgaatttaga gttggagcta ttataagtta tacttttgca
    81061 gataatggta tgtactctgg agatgacggt gtagatgtaa taacgagtag cgaatatcta
    81121 aaaaaattaa ctggtgtaga taagtataac ttagtttatg cagaccttaa tgaaaatgca
    81181 aacaagaaaa aaataaataa ccttttaggt aaaattggaa gtgaagtttc tggaactaca
    81241 acagtagata tgatggtaga aaaagaaaat tctgataaga tgacatctag aactatgatt
    81301 tatagttatg gcatagtagc aataatgttc ataatcagtg tacttaacat aataaacaac
    81361 ataagttata acttaacttc aagaactagt gaatttggaa tgttaagagc tattggtatc
    81421 tctgagagag gatttaaaaa tatgatactt tatgaaggaa tattatatgg tgtactctca
    81481 agtataatta ctattgtgtc aggacttata atacaattta aaatgtatta cacgcagggc
    81541 tttgtatcat atggattagg attttcaata gattacaaaa tatacatact agttgttgta
    81601 gcaaatataa ttgtaggtat tctagctaca tatattccat caaggaagat aaataaaatt
    81661 agtatagttg aagctataaa cattacagaa taggagggat aattatgcct atattggaaa
    81721 ctattaattt aggtaagatt tatggaaaaa aggaaacatc tgtacatgca ctaaagaatg
    81781 caaatttaaa aataaataaa ggcgaatttg ttgctataat tggaccaagt ggaagtggga
    81841 aaagtacatt tctacattta gtaggtggtc ttgagagacc aagtaatggt actataaaag
    81901 ttgctggtaa agatatatgt tgtctttcag ataaagaact agcaagatat agaagacaaa
    81961 aagtaggatt tgtctttcaa caatataacc taattcctgt attaaatgta aaggaaaata
    82021 tagaattacc attaaagtta gacaataaaa aaatagataa agaatatatt gaagacctta
    82081 taaatttatt ggggcttaat gaaaggaaaa atcatcttcc caaccaatta tctggtggtc
    82141 aacagcaaag agttgctatt gcacgtgctt tatctgcaaa accaagtata atcctagcag
    82201 atgaaccaac aggaaatttg gacagtaaaa ctacagaaga agtcatggat ttactaaaaa
    82261 gttctataaa aaaatataac caaacactta taataataac acataatgaa aatattgcta
    82321 gaaaagtaga taaaattata tctataatag atggagagct taaattaaca ctctaaaact
    82381 atttatagaa aagaggattt aaatgttatt gattttaggt aatttaaatt taaacttgga
    82441 ttttgactac agaataataa gagaagaaaa tgatgatgta gatatattca tagatattaa
    82501 ttatcgtagc ttagatatag atactgatgg ttctaactta tttaattcta gaatacaatt
    82561 tccatttgta agagcattaa ttctaaggct aaataagaac aatcaatgta tgacaattca
    82621 tttgttaaga gatatagatt tattctctgc ttttgccaac tttgaagtgg attatactga
    82681 ctctataata aatataaaaa atcaaaatga gaaagtaatt ttaaataaat ctatcaaaaa
    82741 atagtaaggg ggccttaata ggccccaatt tttttctttt ctaaatttat tatatcatga
    82801 taaataaatt agtcaataga attttctgaa tatttttata attttttcat aaagtttttt
    82861 atatattatg ctttaaaatt atatgtaata gaaaattttt ccgactaatt ttaaagttac
    82921 tttattaaat acacatattc aaaattgaca ttaaattatt gactttttat catttcaatt
    82981 tagaatttaa gttattattt ataactattt atacgtatct ctaataaaac tctatttata
    83041 ttcaagtcca ataatttata tacaaaacca atagaaccta tgttgtacaa tgaatattat
    83101 ttaccataat aaacttttag atatatctct tttaattcac tcatcaatgg gtatctagga
    83161 ttagcacctg tacattggtc atcaaaagct tgttcaacca tagcatccag tccttctaag
    83221 aatttagatt cttctactcc agcctctttt atagtcttag gaagacctac ttttgccttt
    83281 agttcatcta ttgcttttat aaggttatct actttttctt ggtctgtatt tcccttaatt
    83341 cctgcaaaag aagcaaattc agcatatctt tgtatacaat caggatatct gtattgtgag
    83401 aatgcaccca tcttatttgg agcttctgca caattaaact tgattacttc atttattaat
    83461 aatgcatttg caacaccgtg ttgaacatga tggaatgcac ctaatttatg tgctaaagag
    83521 tgacatattc ctaagaaagc atttgcaaaa gacattcctg ccatagtaga tgccattgcc
    83581 attttttctc ttgcttcttt atcattcttt ccatttttat atgcacgagg taaatattca
    83641 aatattattt tacctgcttg tagagctaaa ccgtcagctg gttcagttct taacatagat
    83701 acatatgctt ctagtgcatg tgttaaagca tcaacacctg atgacgctgt tagtcttggt
    83761 ggcatctcca tcatcatatc agcatcaatt atagccatgt ttggcattaa ttcataatct
    83821 gctaatgggt attttacgcc tgaatcttgg tcagttataa ctgcaaatgg agttacctct
    83881 gaaccagttc ctgctgaagt tgggatagca gcaaagtatg ctttttcacc catcttaggg
    83941 aatacatata ctctttttct tatatccata aatctcatag ctaagtcttg gaaatctact
    84001 tctggatgct catacattac ccacattatc ttaccagcat ccattgcgct acctccacct
    84061 acagctatta ttaaatctgg ttggaaatca gccatagctt tagctccttc tcttgcacaa
    84121 gctaatgttg ggtctggagc tacatcaaag aatgtagtgt gcttaattcc catctcatct
    84181 aataaatcag ttaacttctt agtatatcca ttattatata ggaaagagtc tgttactata
    84241 aatgctttct ttttatccat aacatcctta aattctcttg ctgctacacc taaacatcct
    84301 tttttgaaat aaactttttc tggtgctctg aaccaaagca tattctctct cctttcagct
    84361 actgtcttga tattaagcaa atgtttcact cctacgtttt cagatactga gtttccaccc
    84421 caagaaccac aaccaagagt aagagatggt gccaatttaa agttatataa atcacctata
    84481 ccaccttgtg atgatggagt attaactaat actctacaag tcttcatagc atttacaaac
    84541 ttttctactc tctctggatg atttatagag tctgcatata atgaagatgt atgaccatat
    84601 cctccatctg caactaattt ttctgctttg gcaactgcat cttcaaaact tttagacttg
    84661 tacattgcaa gtacaggaga aagtttttca tgtgcaaaag gttcatttaa ttcaacagat
    84721 tctacttcac caattattat tctagctgtt tttggaactt ctacatctgc cattttagct
    84781 attatatgtg ctggttgtcc aactatttta gcatttaatg aaccatcaat tattactact
    84841 tttcctactt tttccgtttc ttctttattt aagaaatgtg caccacgata tttaaattct
    84901 tttttaactt cttcatatat tttttctggc acaattactg cttgctctga agcacatatc
    84961 ataccattgt cgaatgattt tgatactaat attgaactta cagccatttt tatatctgca
    85021 ctctcatcta ttattgcagg gacatttcca ggtccaactc caacagctgg cttacctgag
    85081 gaatatgcag atttaaccat tccaggtcca ccagtagcta atataaggtc tgcctctgcc
    85141 atgacaacat tagttaattc aatcgaagga acatctaccc aacctataag accctttggt
    85201 gcgcctgcct taactgctgc atcatgtaca actctagctg cttctatagt acagttttta
    85261 gctcttggat gaggagagaa aattatacca tttctagttt ttagtgctat tagggatttg
    85321 aatattgcag ttgatgtagg attagttgta gggataactg ctgataaaac acctactggt
    85381 tcagcaattc ttgtaaaacc aaatgcttca tctttttcta ttacaccaca agttttagtg
    85441 tctttataag cattatagat atactctgaa gcaaaatggt tttttataac cttatcttca
    85501 acaataccca taccagtctc ttccactgcc atttttgcta aaggtattct ttgttgatta
    85561 gctgcagttg aggcagctaa gaaaatttta tctacctgtt cttgcgtaaa tgttgcaaat
    85621 tctttttgtg ctaatctaat ttcttctaat ctcattctta atgtttcaac actgttgaca
    85681 atttcaggac tacatacttc aacacttgat ttttctacta cattttcttt tttctccata
    85741 ctacaaacct ccctaaaata attatacatc tacaattttt ataaatctta aatacatcat
    85801 ctgtactttt aacttatact taaaataatt ttatagattt catctctata ccttagattt
    85861 tatttacttt actttcttag gtcaagaagt ttttttctga atattttgtc aatttatttt
    85921 ttaacaaata tattactttt tttactttta ctaaattttt ttatctaaat gagatatatt
    85981 tcatttgaat aatttacttt gactaaataa aatactaaaa tgataattta tatctttcat
    86041 tttttttact tattaaattt tatatgttat ttgtacaagc agtaaataaa atttttgtcg
    86101 tatttttata aaataacact tatttttgac ttgtgtgcaa tttttctttt tatagcaact
    86161 gtatggtttt aaaaaatata caaactaaaa ttattctaat ttctataagt tatttttaag
    86221 tcaatataca ataattatac ttttcatatg gataaataat ttttatattc atcccgttaa
    86281 ttttttaatg ataatatata tacaaaattt tttacagtat aaaatagtta taaattttta
    86341 gtttattaac atattaatta attttttctc aggtaaattt aatca
//
LOCUS       DBGJFK010000009        81175 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.009, whole genome shotgun sequence.
ACCESSION   DBGJFK010000009 DBGJFK010000000
VERSION     DBGJFK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81175
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.009"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            36..770
                     /locus_tag="ACOIAP_000777"
     CDS             36..770
                     /locus_tag="ACOIAP_000777"
                     /inference="COORDINATES: protein motif:HMM:NF027650.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2637686.1"
                     /translation="MRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGK
                     LSGGERRRLHLLKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRY
                     FLDRICNKIFSYEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSITPKKE
                     KPKNDKKLKFSYNEQREFENIDSDIEKLESKIATLDESTSKFSTDFTKLQEILNEKSK
                     LEKELEYKYERWEYLNNLADEIANNK"
     gene            complement(1019..1366)
                     /locus_tag="ACOIAP_000778"
     CDS             complement(1019..1366)
                     /locus_tag="ACOIAP_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HGZ2637687.1"
                     /translation="MSKSNDVLDIVFKITNGLEYEVDENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(1353..3284)
                     /locus_tag="ACOIAP_000779"
     CDS             complement(1353..3284)
                     /locus_tag="ACOIAP_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OPT family oligopeptide transporter"
                     /protein_id="HGZ2637688.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGVAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSTGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVS
                     GMTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGS
                     KNEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGS
                     LPWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEK
                     EKEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVL
                     VVLTALPIILSKVKNNEQE"
     gene            complement(3695..5884)
                     /locus_tag="ACOIAP_000780"
     CDS             complement(3695..5884)
                     /locus_tag="ACOIAP_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HGZ2637689.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDKDILIEDL
                     EFVCKEEEKVLLEDFNDNQYEVPHDKSYVDLFREQVKVTPSNIAARDENRNLTYKELD
                     EVTDKLAGYLNYIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLEYELTEKITPSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSINATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYKKRNYELYNEYGPTEFTVISTSFHVDREYGKIPIGKPISNTYAYVLDKKNKLCPI
                     GVPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDEGDMYICAYYVIGDED
                     SDKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE"
     gene            6218..6949
                     /locus_tag="ACOIAP_000781"
     CDS             6218..6949
                     /locus_tag="ACOIAP_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HGZ2637690.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLEIDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLKKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTD
                     LILNIELKTDKVNYPNIEKDVLELILKYNIKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIEICHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLQSKQYR"
     gene            7029..7664
                     /locus_tag="ACOIAP_000782"
     CDS             7029..7664
                     /locus_tag="ACOIAP_000782"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HGZ2637691.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAK
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTSKSIELLSYPVHCLENDIES
                     ELVDELKSIENLKILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(7916..8509)
                     /locus_tag="ACOIAP_000783"
     CDS             complement(7916..8509)
                     /locus_tag="ACOIAP_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HGZ2637692.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(8580..9443)
                     /locus_tag="ACOIAP_000784"
     CDS             complement(8580..9443)
                     /locus_tag="ACOIAP_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HGZ2637693.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLSYKGYL
                     AGNDDIRARDIEGMFLDKDVDMIMCLRGGYGTTRILDKINYEIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVAKWDEFTYKSLVNALEFKDDLYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEEKDLIELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            9606..10775
                     /locus_tag="ACOIAP_000785"
     CDS             9606..10775
                     /locus_tag="ACOIAP_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2637694.1"
                     /translation="MLNIRTLCNEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVNPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLKNPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIKGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIKE
                     ICDFTCKTFGGSISVEIEEGYPALINSNYLVDYVKQNAVELFGKENIILKDAPTLGAE
                     DFSYFLKHCEGAFYHLGCANREKNIISPLHTSTFDIDEGCLITGVMLHVKNVLAF"
     gene            10876..11352
                     /locus_tag="ACOIAP_000786"
     CDS             10876..11352
                     /locus_tag="ACOIAP_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HGZ2637695.1"
                     /translation="MKEILINPIGKIRIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTTVQIISIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSIDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            11918..12712
                     /locus_tag="ACOIAP_000787"
     CDS             11918..12712
                     /locus_tag="ACOIAP_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HGZ2637696.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEIAAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKRIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            12736..13179
                     /locus_tag="ACOIAP_000788"
     CDS             12736..13179
                     /locus_tag="ACOIAP_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HGZ2637697.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFSITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDKDKKKP"
     gene            complement(13268..14554)
                     /locus_tag="ACOIAP_000789"
     CDS             complement(13268..14554)
                     /locus_tag="ACOIAP_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGZ2637698.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKKDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHINDLCDKYKDRLFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTKENLLDILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKAFGKNEEIVINPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDNAKQMTKEIEETIF"
     gene            complement(14772..15662)
                     /locus_tag="ACOIAP_000790"
     CDS             complement(14772..15662)
                     /locus_tag="ACOIAP_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGZ2637699.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            15954..16298
                     /locus_tag="ACOIAP_000791"
     CDS             15954..16298
                     /locus_tag="ACOIAP_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGZ2637700.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEILAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(16459..18555)
                     /locus_tag="ACOIAP_000792"
     CDS             complement(16459..18555)
                     /locus_tag="ACOIAP_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HGZ2637701.1"
                     /translation="MIKFKLYISGLYSGNVIFDDDLLIEKLNPFTNKIESLKPISREE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWDKTHKDEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPNFIDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWKPMIHEREDGDSTINWIVSQEWSDGTVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNGMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPIEYYSVGSNIWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDSRLEEKCDSYIYNPKDPSIQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDVFSEEF
                     TITGDIKLEFFASSSARDTDWVIKIMDVDLDGNSIKLADGILSARFRNGFYESEFMEE
                     GKIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(18568..19728)
                     /locus_tag="ACOIAP_000793"
     CDS             complement(18568..19728)
                     /locus_tag="ACOIAP_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HGZ2637702.1"
                     /translation="MNTLFSNPGSILAVMTLMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFTSFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(19747..20814)
                     /locus_tag="ACOIAP_000794"
     CDS             complement(19747..20814)
                     /locus_tag="ACOIAP_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HGZ2637703.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVISVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNVPLYKVLGGFDSKVQTDITISIDKPEKMAIEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNIKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKSISGGF
                     VMDGDIMNLLNKPGLGIEVNL"
     gene            21165..21731
                     /locus_tag="ACOIAP_000795"
     CDS             21165..21731
                     /locus_tag="ACOIAP_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637704.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTPEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDVCMGEKIVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(21949..22935)
                     /locus_tag="ACOIAP_000796"
     CDS             complement(21949..22935)
                     /locus_tag="ACOIAP_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HGZ2637705.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSISGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYISTFIQEKDF
                     TINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSKGEVEKFLSNEYKVTNEIDRMGCRLD
                     GESIKHINGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(22965..23660)
                     /gene="pxpB"
                     /locus_tag="ACOIAP_000797"
     CDS             complement(22965..23660)
                     /gene="pxpB"
                     /locus_tag="ACOIAP_000797"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HGZ2637706.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLKIDFDSLIESLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEIPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(23680..24900)
                     /locus_tag="ACOIAP_000798"
     CDS             complement(23680..24900)
                     /locus_tag="ACOIAP_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGZ2637707.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(24929..25720)
                     /locus_tag="ACOIAP_000799"
     CDS             complement(24929..25720)
                     /locus_tag="ACOIAP_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HGZ2637708.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVNKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNAEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            26307..26936
                     /locus_tag="ACOIAP_000800"
     CDS             26307..26936
                     /locus_tag="ACOIAP_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HGZ2637709.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAKTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(27047..28561)
                     /gene="glpK"
                     /locus_tag="ACOIAP_000801"
     CDS             complement(27047..28561)
                     /gene="glpK"
                     /locus_tag="ACOIAP_000801"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGZ2637710.1"
                     /translation="MEKKYIMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDKDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASIQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVNIDRPKIVETTALGAAYLAGLS
                     VGFYIERNEITSKWQVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            28805..29347
                     /locus_tag="ACOIAP_000802"
     CDS             28805..29347
                     /locus_tag="ACOIAP_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2637711.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLDIIFTEIRNFINKVHNVQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            29352..31853
                     /locus_tag="ACOIAP_000803"
     CDS             29352..31853
                     /locus_tag="ACOIAP_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2637712.1"
                     /translation="MFTLNSNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPAR
                     TIIQNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLI
                     CGLSSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIA
                     NILGSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGT
                     LMLVCIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILS
                     FEYFLNPRILIILILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGVA
                     APLSGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCLSLMFMGLGMGFT
                     MGTPLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDL
                     VGKPSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKY
                     LLDKVQSADTTNITNITKEISTTMFDEKVPSIISKIQKNVQKGIDGTQSGINGIEEGE
                     SKLNSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGIDKGIKGMEQGLKKQDKAIDE
                     LTTAYNKIPTTEKIPTNNENNSNEQNQDNASNSESDATNNDSTENKNNNSNDNKPNLN
                     EQKESLNAQIQKLKKTRNELNAKLQKNKAQKNELSKKLKSMESQKKELQSKLNNSINQ
                     KKDMEKSLDTMQQQKKSLQAVLEKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTL
                     QSTLNSGFKQMYITVFCVNLLAFVILLFYKENKTR"
     gene            32271..32669
                     /locus_tag="ACOIAP_000804"
     CDS             32271..32669
                     /locus_tag="ACOIAP_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637713.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     IVMSIADYFNVTTDWLLYGKEKVNSNNSVKEDKEDYLHINNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(32886..33095)
                     /locus_tag="ACOIAP_000805"
     CDS             complement(32886..33095)
                     /locus_tag="ACOIAP_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637714.1"
                     /translation="MCKLDSDGVIECCKAIDDFITALSNIKSLNMERLNILTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(33127..33336)
                     /locus_tag="ACOIAP_000806"
     CDS             complement(33127..33336)
                     /locus_tag="ACOIAP_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGZ2637715.1"
                     /translation="MDARRKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            33632..34051
                     /locus_tag="ACOIAP_000807"
     CDS             33632..34051
                     /locus_tag="ACOIAP_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2637716.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSISEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKDKNLKKTEYNKTKDEKIDK"
     gene            34279..34734
                     /locus_tag="ACOIAP_000808"
     CDS             34279..34734
                     /locus_tag="ACOIAP_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637717.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(34945..35205)
                     /locus_tag="ACOIAP_000809"
     CDS             complement(34945..35205)
                     /locus_tag="ACOIAP_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637718.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(35468..35821)
                     /locus_tag="ACOIAP_000810"
     CDS             complement(35468..35821)
                     /locus_tag="ACOIAP_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1375 family protein"
                     /protein_id="HGZ2637719.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQNKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLSQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(35838..41015)
                     /locus_tag="ACOIAP_000811"
     CDS             complement(35838..41015)
                     /locus_tag="ACOIAP_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome condensation regulator"
                     /protein_id="HGZ2637720.1"
                     /translation="MKQNKLLQRGAYFNDKNILIDDFDKRYNDYDFVEFFTGISNSTF
                     GLKSDGNLYACGDNTGFQLGLGKDSSERRMFSKVKIDNVKYVSCGSKHSVAVTKDGFA
                     YGAGTSNVGQLGVIESTVYYEFTKLPIYDVKTVACGYDFTFVLKNDGTLYSAGLNSSG
                     QLGLGDTNNRATFTKVNIDSVKDVITYNQSVFIIKMDGTAHACGLNSNGQLGINSTLN
                     KSVFNKIEGMDNVKQIACGSSHTILIKNDGTMYTTGYNGVGQLGTGNNNNSIVFTLSS
                     INNVKYASCGNNHTMILKYDNTLFSTGQNNYGQLANANKDVASRNTFVKVNVENIKDI
                     KCGSQFNFLINGSKEIFVSGCNLAGQLGSFFHTTFLYEFSKVQSSNLDNYSGLLVNDD
                     YLYVTKDNSEFLNVKLSDNFQDYKKIELTDNNMFIVMNDGTLYACGLNNYGQLGLGDT
                     VNRSVMTKVDIDNVLDIKGNGNSTFVLKNNGTLYSCGLNNYGILGLKDEVNRNIFTKI
                     EIENVKEFCVESEYIIALNHSKEVYGWGYSANSNIERTSNYPDKQNINGIEKIATYYR
                     SVYMINSEGKLYVSGYNSYYQLGTGNSSSTNKTLVSKYRTVTLSTSSSNLSDLPKIVN
                     VFPFNYGCAIIDKSGFVYLAGQHRYPDTSKSNPSINDYSRYGSFIETTSSYYNTYFTQ
                     VNAFNGIEKVIGTSNNILYFKKGSTYVTGYPKTFGSSATGYKSYTTISSEYSNLGSLF
                     IITSSSSKLYGHGVANNGEFGNITNLDGVSSYDTGLKDIKDIIVKNNTVVVVDKNNNI
                     YVTGTNQFNKLGIGEYNNQPIRKFTNITEQSNSFIFMDDIKEITTSRNTMFIVKNDGT
                     AYATGNNSSGQLGLGDIINRNKFTQINLDNIKKISTSIDGNTTFAIRNDGALYSTGLN
                     TKGQLGLGDIVNRNTFTKVNIQNVRDVVLGTTHSHAIKDDNTLYSCGENTHGQLGLGS
                     ESNHPDVLTFTVNNITNVRDVYCSDTTTFIVKDTNIAYCCGYNNNSQLGMGNTTDQYS
                     FIKCMENVKEVIPNEINTYIITIYNTAYSTGLNTDYCLGLNSNSNQSSFSEIPISNVV
                     KVAPNRNNAVLLLTSEGDVYTAGKCSNGSGTGSETPEKIKKIASKAKDIGMNYRCGHY
                     VSDNGDLYGTGFNDCGQLGVGDVTKRDTFIKTNTRVKKILPLEYANIAIKDTNDIYIC
                     GLNNYGQLGVGNRYDSRNNDNRIFNYKHMNFVMGDLTSIKNRHNFILLNNKIVIPTTK
                     DIDYGLVLGNLYKGDLYTELPYENIKEVSISKTHIIILLNDGTMYGCGTNYHGELLQD
                     LSINQVDEFVQINVSDVKHVSCGDNFTYFIKSDDSLWSIGKNSEYQLGIGHNNPVTEL
                     QRITTVSSCKEVHCGKNYTLVVTTGNELFVQGYNDKGALGLGSDNENAIIKFFTKALT
                     DIREIKSYGSDHILVLKNDNSVWVTGKNRDVYKIEQPVEFLKEFTIVPISEDVNTVKD
                     VLATDNTLYIISEVGTTNAAIEITEKSISSIKIKIQDPNKDISRIEMLINGESVKSVS
                     DLTTEKISFEVPPDKIKIGENKILFRAYCKGDDLYASLFIFKESTGNSIIKDSYVMIG
                     NRMYKVVNTTSNEQDITITLDRGLEEDLNLGDPIYQLINKTKVQVKINKSDLFKDMKL
                     VEIKKSDSSYQEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(41037..42023)
                     /locus_tag="ACOIAP_000812"
     CDS             complement(41037..42023)
                     /locus_tag="ACOIAP_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGZ2637721.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVNIGDVNILTTDSKDLSGAINEVVKKIENISFDDVISGQIQTDISVLKNSY
                     NKLSEKVLDILIYLELESEVTVDEAGYWYDTLTNGNNIVAIEGLKLDLNRKCITGEIG
                     NVIFRDVVLPFSANRVRYIHDMDNNFVETKSSNTYLKEQKDITLSKYSYEIR"
     gene            complement(42024..42722)
                     /locus_tag="ACOIAP_000813"
     CDS             complement(42024..42722)
                     /locus_tag="ACOIAP_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail protein"
                     /protein_id="HGZ2637722.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSIVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(42719..43771)
                     /locus_tag="ACOIAP_000814"
     CDS             complement(42719..43771)
                     /locus_tag="ACOIAP_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HGZ2637723.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMISGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGENGTVINNGTVI
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKRYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEINISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTAGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(43764..44192)
                     /locus_tag="ACOIAP_000815"
     CDS             complement(43764..44192)
                     /locus_tag="ACOIAP_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HGZ2637724.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVSVRSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(44192..44518)
                     /locus_tag="ACOIAP_000816"
     CDS             complement(44192..44518)
                     /locus_tag="ACOIAP_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HGZ2637725.1"
                     /translation="MANPINEFIGIIREEGKHHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMLDRQIETFDTETNQEHKHEVKNPFIDTFESGDMVIMFRIGEKFAIV
                     SKLVSL"
     gene            complement(44534..46063)
                     /locus_tag="ACOIAP_000817"
     CDS             complement(44534..46063)
                     /locus_tag="ACOIAP_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HGZ2637726.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLMQSEVSYNFKDKLVEDIAK
                     QVFAENRISVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEGYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRKDFNTARRV
                     L"
     gene            complement(46345..46767)
                     /locus_tag="ACOIAP_000818"
     CDS             complement(46345..46767)
                     /locus_tag="ACOIAP_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HGZ2637727.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKATVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(46767..49220)
                     /locus_tag="ACOIAP_000819"
     CDS             complement(46767..49220)
                     /locus_tag="ACOIAP_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637728.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASSRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNELNSNIMIILIFKAKSDEIEKTKNKLLGNLKKIGGK
                     VWKIVIKAKDMTKRVISSILGNLKRVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASSIISKVFPKLRLFAGKVWRGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQRDVDNYYEDLLDIADKTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSSKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KVTSKLVSSIKMAQLGGVL"
     gene            complement(49220..49387)
                     /locus_tag="ACOIAP_000820"
     CDS             complement(49220..49387)
                     /locus_tag="ACOIAP_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637729.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(49414..49860)
                     /locus_tag="ACOIAP_000821"
     CDS             complement(49414..49860)
                     /locus_tag="ACOIAP_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGZ2637730.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(49974..50402)
                     /locus_tag="ACOIAP_000822"
     CDS             complement(49974..50402)
                     /locus_tag="ACOIAP_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HGZ2637731.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(50416..51480)
                     /locus_tag="ACOIAP_000823"
     CDS             complement(50416..51480)
                     /locus_tag="ACOIAP_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HGZ2637732.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAILGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(51485..51928)
                     /locus_tag="ACOIAP_000824"
     CDS             complement(51485..51928)
                     /locus_tag="ACOIAP_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HGZ2637733.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEESCFFVSILS
                     VICTPIMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYALNFSVTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(52177..52617)
                     /locus_tag="ACOIAP_000825"
     CDS             complement(52177..52617)
                     /locus_tag="ACOIAP_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637734.1"
                     /translation="MENKKDILFKETDERLHNYKYLDIKIKNINLDIKRYENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKIEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIVKLSEIL"
     gene            complement(52721..52918)
                     /locus_tag="ACOIAP_000826"
     CDS             complement(52721..52918)
                     /locus_tag="ACOIAP_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2637735.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            53087..53407
                     /locus_tag="ACOIAP_000827"
     CDS             53087..53407
                     /locus_tag="ACOIAP_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637736.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFDVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            53489..53995
                     /locus_tag="ACOIAP_000828"
     CDS             53489..53995
                     /locus_tag="ACOIAP_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGZ2637737.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGMKIISLL
                     SNLKQNTKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIIGIINSGVTCVYEMADILNVEINFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            54696..55451
                     /locus_tag="ACOIAP_000829"
     CDS             54696..55451
                     /locus_tag="ACOIAP_000829"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGZ2637738.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(55594..56022)
                     /locus_tag="ACOIAP_000830"
     CDS             complement(55594..56022)
                     /locus_tag="ACOIAP_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGZ2637739.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(56443..56643)
                     /locus_tag="ACOIAP_000831"
     CDS             complement(56443..56643)
                     /locus_tag="ACOIAP_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGZ2637740.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(56826..57980)
                     /locus_tag="ACOIAP_000832"
     CDS             complement(56826..57980)
                     /locus_tag="ACOIAP_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HGZ2637741.1"
                     /translation="MKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNMEEKVM
                     ESANIEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYENEVKK
                     MKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQKDKENA
                     FRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGVELQLT
                     DEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGRFKKNS
                     IWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFVGYEKK
                     GRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            58231..59052
                     /locus_tag="ACOIAP_000833"
     CDS             58231..59052
                     /locus_tag="ACOIAP_000833"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HGZ2637742.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVHFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDENILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(59128..60525)
                     /locus_tag="ACOIAP_000834"
     CDS             complement(59128..60525)
                     /locus_tag="ACOIAP_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2637743.1"
                     /translation="MRILVGKKFNNKKIVTLRTVFVRYSSLFFAITVVLVSILILSFP
                     ILLSLNIILPANYVEKQIYENKDKIISSKQVTKDLIPDLCEYGVYTLNGKVISGTFNK
                     NESKEVWDLMRGFERRTITSSKNYIKLSRKNEVCIIRYSIVAEFVSPTLRTYLPKPEL
                     LGMIIFSIIFLIEIIILSKLFGKKLNAEMELLKNTTEKIEQQDLDFVIESSKIREINN
                     VLFSMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENP
                     ELSEYMEYIAKGATQIEKYINTLIEISKTETGYILNKEVINVSEFIEDILIQIEALAR
                     TQNLNVEFSKQGNLPESITIDKELLFRAIMNVISNAIDYSPSQSKLYISVSVSNKYLK
                     FVITDCGSGFSKADLSKATGQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILHIENS
                     IKTGGAMVTIEIPIV"
     gene            complement(60653..61423)
                     /locus_tag="ACOIAP_000835"
     CDS             complement(60653..61423)
                     /locus_tag="ACOIAP_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HGZ2637744.1"
                     /translation="MTQLVRIFCSDLIKLKRTFIILMHFCIALIGMGLCLGYYKYSSA
                     DDISKIAAYLQVIAIAFPLLSSIMCSLCIEQEYYSGSYKHMLTSSNPKYLTLISKYII
                     LICLGFGATLVSVLGFKFGVSSISNEVYFTLDFYMISIMILVGSNLFVYILHLFLSLR
                     FGKGASIGVGIVETLLSAVLLTGLGARIWPYIPCVWGVRFISIWSSFSSSKTIEYIKV
                     ESIKGYQSIGLVCGFVTILAFIILCIWFSKWEGKKSEE"
     gene            complement(61425..62144)
                     /locus_tag="ACOIAP_000836"
     CDS             complement(61425..62144)
                     /locus_tag="ACOIAP_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HGZ2637745.1"
                     /translation="MEKLVRAEFQKMKRTFGIRLIWIAPIFSIIITFLLGGGQNGVYN
                     WWYTMFLPGVLTLISSLIVQKDEKKKYRGILSLPIEKKDVWTGKILYCIICCFITSII
                     FMIGIFLVGMLYKEVISVSQNIIGTILLVLLFMWQIPLCMFLASKFGMFITIIINMFF
                     TIIGVAVFSTTEMWYAFPYSITPRLMAPVLHILPNGLPVPEGSEFLNSNVILPGVLIS
                     IVLFILLSLATNAWFNNREVK"
     gene            complement(62146..62853)
                     /locus_tag="ACOIAP_000837"
     CDS             complement(62146..62853)
                     /locus_tag="ACOIAP_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HGZ2637746.1"
                     /translation="MSNYILEVKGVSKKFKDEVVVDNISIAIKHNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLKIVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVLGYQGEVSKEQN
                     LEELFMKVVAENRKRGN"
     gene            complement(62973..63509)
                     /locus_tag="ACOIAP_000838"
     CDS             complement(62973..63509)
                     /locus_tag="ACOIAP_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637747.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDDD
                     VREETTSKMINSKNTTKIPIEIISKDGKIVKYLQIDEESTLKDKLRLILDTLSKEYFN
                     GLDMEVEVKEKDNLVKINLIEPDEKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(63611..64681)
                     /locus_tag="ACOIAP_000839"
     CDS             complement(63611..64681)
                     /locus_tag="ACOIAP_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HGZ2637748.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDVSVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSKDEGVFINNIEEYIPENVNIKEKIGRHSNYDNEFNLYSNMPIAKYLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEVIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNRLEL"
     gene            complement(64674..65732)
                     /locus_tag="ACOIAP_000840"
     CDS             complement(64674..65732)
                     /locus_tag="ACOIAP_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGZ2637749.1"
                     /translation="MSLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIISSLGSPKSIAKELILQTKEKNIQEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMSTDILNGKFSRFKSNIKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSVTIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGIEILAWQLLLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLKDIENKKGEDKYE"
     gene            complement(65719..66051)
                     /locus_tag="ACOIAP_000841"
     CDS             complement(65719..66051)
                     /locus_tag="ACOIAP_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2637750.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DKGGNELE"
     gene            66250..67371
                     /locus_tag="ACOIAP_000842"
     CDS             66250..67371
                     /locus_tag="ACOIAP_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2637751.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKESIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDFSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKEICCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSDSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYRLVS
                     NEFDSIINFMKKNLEEFKTVIHPEKIADYISELIDKHYS"
     gene            complement(67499..69397)
                     /locus_tag="ACOIAP_000843"
     CDS             complement(67499..69397)
                     /locus_tag="ACOIAP_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGZ2637752.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLDDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVSPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEEGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAVENKDYQAASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            69712..70488
                     /locus_tag="ACOIAP_000844"
     CDS             69712..70488
                     /locus_tag="ACOIAP_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HGZ2637753.1"
                     /translation="MEYIIFDLEFNQGFDKKFNKTISNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKEIHPFISRMTNIKDSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFILEDAKQRKNK"
     gene            complement(70580..71332)
                     /locus_tag="ACOIAP_000845"
     CDS             complement(70580..71332)
                     /locus_tag="ACOIAP_000845"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGZ2637754.1"
                     /translation="MRFISWNVNGIRACAGKGFLDFFKEVDADVFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLISADIHTEVLGSDHCPVELEIK"
     gene            complement(71453..72403)
                     /gene="galT"
                     /locus_tag="ACOIAP_000846"
     CDS             complement(71453..72403)
                     /gene="galT"
                     /locus_tag="ACOIAP_000846"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HGZ2637755.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDKEC
                     PFCKGNEAYATDALFEIEGEEGWLVKSVYNKFPIIDDMARDIYGVHEVMIESSKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLNRRVVYNGEAFLVIIPYATKYSGE
                     VRIIFKDKIKFGELNDNNIKELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEELTKKLKID"
     gene            72788..73984
                     /locus_tag="ACOIAP_000847"
     CDS             72788..73984
                     /locus_tag="ACOIAP_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGZ2637756.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYNMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(74203..74655)
                     /locus_tag="ACOIAP_000848"
     CDS             complement(74203..74655)
                     /locus_tag="ACOIAP_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGZ2637757.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(74956..76401)
                     /gene="purB"
                     /locus_tag="ACOIAP_000849"
     CDS             complement(74956..76401)
                     /gene="purB"
                     /locus_tag="ACOIAP_000849"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGZ2637758.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYNSSYAVSGQTYTRKLDYQVVSILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINKRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(76540..77451)
                     /locus_tag="ACOIAP_000850"
     CDS             complement(76540..77451)
                     /locus_tag="ACOIAP_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2637759.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKKY"
     gene            77708..78532
                     /locus_tag="ACOIAP_000851"
     CDS             77708..78532
                     /locus_tag="ACOIAP_000851"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGZ2637760.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKRPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            78572..79102
                     /gene="lepB"
                     /locus_tag="ACOIAP_000852"
     CDS             78572..79102
                     /gene="lepB"
                     /locus_tag="ACOIAP_000852"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGZ2637761.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRIIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKIFAMGDNRENSNDSRFPDVGMIDEDEILG
                     KVMVRLLPLDNIGKVD"
     gene            complement(79182..80963)
                     /locus_tag="ACOIAP_000853"
     CDS             complement(79182..80963)
                     /locus_tag="ACOIAP_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HGZ2637762.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINKDVKVVPKVTPFKGIN
                     TDLLYVKDGKILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLDEYLNDENDEINLNLFLLDVC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEEVQIKDVISIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLIIFTHTKQLRNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKAFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        27159 a        13294 c         9256 g        31466 t
ORIGIN      
        1 caggaaccct gtgactttag tcatgggagg ttcagatgag ggctatagac tatgtaaaag
       61 aagctagtga ctatatagaa acttcagatg gtactaggat tacagcttct caaatgtgtg
      121 aaagattcct ttttaatggt actatgcagt atactttgat aggtaaatta tctggtggtg
      181 aaagaagaag actacacctt cttaaaatcc ttatgacagc tcctaatgtg cttcttttag
      241 atgagcctac aaatgattta gacattgaaa ctcttaaaat attagaagaa tacttagacg
      301 aatttaaagg tgtagtagtt acagtatcac atgatagata tttcttagat agaatttgta
      361 ataaaatatt ttcatatgaa ggtaatggaa aaattcatat ctatacaggt aattacagtg
      421 attatcttat ttatagagag attcaaggaa ttgaatttga agaatctaaa aaagaatctg
      481 ttaaaaaaga tgactctatt accccaaaaa aagaaaaacc taaaaatgat aaaaagctta
      541 aattctcata taatgaacaa agggaatttg aaaatattga ctcagatata gaaaaacttg
      601 aatctaaaat tgcaacactt gatgaaagta cttccaaatt ttcaactgac tttactaagc
      661 ttcaagaaat tttaaatgag aagtctaagc ttgaaaaaga acttgaatat aaatatgaaa
      721 gatgggaata tttaaataat ctagctgatg aaatagctaa taataaatga tattaaaata
      781 atcttaagtt taataagttt tgctttaaat ctgtacttta taaatatttt aaagagtgtg
      841 tctcaaaatg aactttttag tttacgagac actcttttta tatgaaatca aatatatttt
      901 catcatttca acaatataaa agaggcttat ctctattttg agacagcctc tttcataatt
      961 tttataatta ccttctaatt tatatgctct aatatatcta taataattct tattatatct
     1021 atatatccag tctttcaata tagtgacaat taacttcaat atgatttaaa aatactaaca
     1081 acctttcata aagtggatga gattcttctc catatttagc ttctaggttc ttgcctattt
     1141 ctctaacagt tctttgacca tcaatttgta aaaaaacaaa acttgaatat tcatctagtt
     1201 ctattttttt gtatttaggt attctagctt ttaatttcct aaaaaacttt tgaattttat
     1261 ggtcctgttt ttcaagtata gtaacaacac tattttcatc tacttcatat tcaagtccat
     1321 tagtaatttt aaatacaata tctaaaacat cattactctt gctcattatt ttttacttta
     1381 gataaaataa taggtaatgc tgtaagcaca actaaaacta ctaataaagc aattgccatt
     1441 gaatttgttg cagcaaatcc acttggtacc tttggagtta caactccagt tacttgtagt
     1501 attataccta ttaaaccaat gatagaacca ccagcaacaa gaccagaaga taaacttata
     1561 ccattagaaa ctttaacttc tttttctttt tcagttttag atactaattc aacaaataaa
     1621 cgaatcaatg ctccaactaa tattatagaa gttgttgcaa ttggtaaata gaatcctata
     1681 gctatagtca ttattggtaa atttaatgca tatagaacga ttgccataaa tactccaacg
     1741 ataatcataa cccaaggtaa actacctgac atgataccag aagttaatgt tgacattaag
     1801 tttgcttgtg gtaatgcaaa ttgtacatta tcaccagttg ctctaagttg gtcagaaagt
     1861 aataaaatta ctcctacaac aactataaca ccaactatac ttgcaattgt aaagtaacgt
     1921 tgcatttcgt ttttgctacc accaataata taagttactt tttgagattg agtataacct
     1981 ccagctatcg caatagcaac aactataaat gaaccaaata aaagtaatga tttattagct
     2041 tctaaatcag tccagcccat tataacaaac actaatgtta caataactag agaagctata
     2101 gtcataccag aaactggaag atttgatgtt ccgattgttc ctgttaaacg accagctact
     2161 atgacaaata ataaagataa taaaagagat atgatagctc caataattgc cataacaatg
     2221 ttaccaccag aaattaagaa tgctgctaaa aatccgataa ctactccacc taataaaagt
     2281 atcatttgta tagatgaacc ttcttctcct tctccagtac ttgacttagc tttaagtgtt
     2341 tcttttatag aagcgattat agttggtata agttttattg caccaataat acctccacaa
     2401 agcatcatac cagcacctat atattttaca taactactag atattgctcc aacatccatt
     2461 tggttaagag gcattgcagg attattccat accatagctc catctttagc catatctgta
     2521 aagtatccta ttaaaggtgc tataccaaag tttgataaaa tacttcctgc aaacattgtt
     2581 aaagaaactt caagccctac tataaatcca attcctaaaa gtagaggatt tacttcaata
     2641 tcaaatttcc atttgtagaa tttgcttcct acaagactca ttacattgtt tgctacattt
     2701 aagaatgaac cagttaatac agtaataaat ccacttatta caaatccaat tcccatgtat
     2761 ttaattgaat ctccaccagc ctctgaagca acaagtgtct cagatatggc cattgattct
     2821 gggtacataa gtttaccatg ttcttcaact attagatagt tgtgaactat agcagcaact
     2881 cctatcccaa ataaaactcc accaactcca acagctaaac cttctaggaa tgtaatttgg
     2941 cttccaatta atataactgc tggtagtacg aaaataaatc cacttgcaac agattctcca
     3001 ccacttgaca taccttggat taagttcttt ccaagaatac cctttgaacg agcaaatgct
     3061 ccaacaaaag cagaacctat tatagctcct ggaatacctg cggcaactgt aagaccagct
     3121 ttcattccag agtaagttgt agatgcggca aaaatggcag ctaaaataat accgataatc
     3181 agtacagcta catttccacc ggttctggac ttatctgtga tgtatggaac gtaatctttt
     3241 ccactaacct caccataagc acccttaggt aattttttgt tcataaaatt ttcacccctt
     3301 ttcaatttgt atatattata acatatatac atataaaact taacttttta ttattttaca
     3361 aatagcgagc caaaactact aaaatttaat actatattat taatttctac ttttagatat
     3421 ttttatgcta attttctttt tatttttcaa ttctactaaa aactattaag atataaaaca
     3481 aaaaattttt ttaatgtaaa attaattttg taaaaaaagt gctttaaaac acaaaaaagt
     3541 ataaaaaata caataatcat tcttataaat aaattttcac catagtaaat atatacagaa
     3601 aattcttttt tttacatcaa ttgattttct tataaaaata ggtgtcataa agaaatatat
     3661 gaaatcactt tacaacacct gtcataataa aaaatcactc tggtagtgct tttttattta
     3721 cttttcctat tggtgtaact ggtattttat ctatcctcat tattattgtt ggaatcatat
     3781 atggaggtag atgctcgttt aaatattctc taatagttct ttcatttatc ttatcactat
     3841 cttcatcacc aattacataa tatgcacata tatacatatc cccctcatca tttgttctcg
     3901 atatacagac aacactttta atttctgtaa tattatttat tatattttca atctcatata
     3961 gctctatcct aaactcatca atttttactt gattgtccat ccttccaata taatctaaat
     4021 ttccatcatc taaccacctt actaaatcac cagttctata cattaactta ttatgttcac
     4081 aagttttgta aggattctct acaaatactt gctctgttag tcctttttta tttaaatatc
     4141 ctcttgatat ttgaatgcct gataggcata actctcctgg aactccaatt ggacatagtt
     4201 tgttcttttt atctaataca tatgcataag tattagatat aggtttccct attggtattt
     4261 ttccatattc tctgtcaaca tgaaaagaag tcgatataac agtaaattct gttggtccat
     4321 actcattata cagctcataa ttacgctttt tatatccttt taatctttct cctccagtct
     4381 gtacaactct aagtgagtta ttattgcaat tttgtataaa taaccttgca aacgctgttg
     4441 gcaacgctag tatagttata tcattttcct cacaatattc atttactgta tattcatcaa
     4501 atttagcttc ttcaggcata atatctattg atgcacctac aagcaaataa gggaatagtt
     4561 gtttcattac agcatcaaaa ctgaaactta agtatatacc acatatatca ttttctgtag
     4621 cgtttataga ttttacacta tagtaacaca tatttactaa actcttatgc tctatagcta
     4681 tggtctttgg cctaccagtt gaacctgagg tagatatcgt atatgcacaa tttgatggtg
     4741 ttattttttc agttaattca tattcaagct taaacatttc ttcatcattt atatcgagta
     4801 ctatggtatt ctcatttaca accttacttt ttagttcgtc tgtagttatc actacttttg
     4861 cattactatc ttcaagaagg taattcaatc tttcttctgg attgcttgtg tctattggaa
     4921 aaaatgctcc acctgacttc ataatcccta tagctgtaat aattatgtta atatctcttg
     4981 gtaacattac agctactatg tcttcacttt ccactcctat ataatttaaa taacctgcaa
     5041 gtttatcagt tacctcatcc aattctttat atgttaaatt tctattttca tccctagcag
     5101 ctatattact aggtgttacc ttaacttgct ccctaaataa atcaacataa cttttatcat
     5161 gtggtacttc atattgatta tcattaaagt cttccaataa tactttttct tcttccttac
     5221 atacaaattc taaatcttct attaaaatat ctttgtcttc tattatttgc tctattatat
     5281 aatcaaattg atttaaaatt cttctaatag tctctctttt atatatagat ggtttatact
     5341 ttatttttat tttaagcgct ctcttagtat atactattac agataaatca tatccctttt
     5401 tttctatgtc ataatcatat gataaatcaa aacttttagc tataaatatt gtgtttataa
     5461 gcttagtatt tagatgattt ttattctcta tatctgataa taaatagtat ccatactcta
     5521 aagacctgct ccactgcctt tttagctttc ttacaacatc tataaatttt tcactttgtc
     5581 taactcgtac tcttattgga attatattca ttgttttacc aaaaactaca tcatcttcat
     5641 atatatactt ttgaagtata agaccatata tagtttctat gatagagtct atgctaatat
     5701 tgttcacttt agaatattga attaaccttt catgtttctc aatattcatc ttaaaaacct
     5761 catctactac ttcatcagaa caatctttat aaaaaaaatc atttggaatt tttgctatat
     5821 tcgtataatc atctaacaaa tccatccaat aattcatagc tcgttctaaa ttaacttcat
     5881 acatatcaaa attccccctt actactaagt ctatataaaa aattcttttg gaattttatt
     5941 tttcacaata tataatatat taataataca tatgcaagct ctaaaagcat gagcttgcat
     6001 aaaattacac ctattattat ggctactaaa ttcgtaatat ttacaatgtt taaaatatat
     6061 tataacacat atatgatttt atttttctac atttatataa tatataaatt acaaatagtt
     6121 atttaattaa tatataacaa taccttttgg aatatgatat attatattaa ttaaattttt
     6181 ataagataag ttatatttat tgaaaggagc cacataaatg aatatttatg ctcatagagg
     6241 gtttagtgga aagtatccag aaaatactat tctagctttt aaaaaatgtt tagagataga
     6301 tatatatgga atagaacttg atgtccacag aactaaggat ggaaaaattg tagttattca
     6361 tgatgaaaag gttgatagaa cttttaatgg acatggtttt gtaaaagact ttactttaaa
     6421 aaagttaaag actctaaact catcttttga aggatatcaa aacaataaag aatgtaaaat
     6481 tccaacttta gaagaagtat taattctaat ttcacctaca gaccttattt taaatataga
     6541 gctaaaaact gataaggtaa actatcccaa tatagaaaaa gatgttttag aacttatttt
     6601 aaagtataat ataaaaaata gagttcttat atctagtttc aacagcaata gtttaaaaaa
     6661 ctttcataaa ttagacccta gtgtaaaaac aggattattg tgttatttac ctataaacaa
     6721 tgtagtcaat tttgctaaat ttctgggtaa tagttacctt catccacctc tagttttagt
     6781 aaatgaatct ctaattgaaa tttgtcataa aaatttactt ggtgtcaatg tatatactgt
     6841 aaatgaagag gatgatatac tacactgtct aaaactcaat gtagatggta tttttactaa
     6901 ctatccagac attgcttcaa atcttttaca atcaaaacaa tatcgctaat tacacaatag
     6961 tttgcactcc ttgactttta tataattaat atgtacaatt ttattaaatt tatcttggag
     7021 gtataactat ggataactta ttaaatgaac ttgaagcttt aaagagtaat ttagataatc
     7081 taccaataga aaaaatagaa aattatgact tgagtaaaac cgctttattt ataattgatg
     7141 ttaataatgg ctttgcaaaa caaggtgcat tatactctcc tagagtagag tctttaataa
     7201 agccaatcga aatgtttaca aaaaaaatat caaacaaatt aaatagagta atagcattta
     7261 ctgattctca tacttctaag tcaatagaac ttttgagtta tcctgttcac tgtttggaaa
     7321 atgatataga aagtgaattg gttgatgaac ttaaatcgat agaaaaccta aaaattcttc
     7381 ctaaaaattc tactaatgga ttttttgcat tagaaaattt ggattttgat aatatagaca
     7441 atataattat agttggcgat tgtacagata tatgtatata tcaatttgca ataactctaa
     7501 aatcatattt taatcagcat aatattgaaa aaaatatagt tgtacctatg aatttagtag
     7561 atacttatga tattcctaac gttcaccctg ctgagatttt aaacttagta ttttttaata
     7621 gtatgattca aaatggagtt aatgtattaa aagagattcg ttaatactct aatactttgc
     7681 atcacatatg atacaattat cagataacta tttttaataa aacctctaat agaaaaacac
     7741 agttttaatg ataagattac aatttaaaaa tattatctac tatgactaat cttcacaata
     7801 taaaaaatcg cagtttagat actccttata aaaatttata aggaataata aattgcgatt
     7861 tttattttta aataatacca ttaatctata ctacttcagt atttaaattc actttttaat
     7921 agtcatactt atttgtagtt tcgcacatta ctacctttat tttcttatta aacatattct
     7981 tatattctaa taaaaactca tttagttctg aatccataag atttattttt ctatcactac
     8041 aaagcattat cttttcttgg tcgattatta cattaatatc atttaagtca ttttttataa
     8101 atgttgttat acaactcttt ggttggattt tttctccata tttttcataa aatcctgcac
     8161 tcttcttaaa tgactctaaa tcttctgtag atactttgct ggaagtatta ttactcataa
     8221 aacctgctgt agaagggtcg attccaaagt ttctaagttg tttttctact tcttcagtgt
     8281 ccataccata tctctccata aattgctttt gtattttcat aaatttttct tgagatatgt
     8341 tgttatctct catataatcg aatatttttc ttgaaaactc agccatagac atctttccat
     8401 ccataacaga aaaatataag ttatatatgt attgctcaaa tttatctaca tcagaatctt
     8461 taactttgtt ctttagttcg ttaaagtcta ttattctatc atcagacatt tttcatcctc
     8521 ctagctaaat ttttacttgt ataagattat accatatttc tattatattt atatacacac
     8581 tattttttta atttaacgat tttttctgta gcatctaatt cgcacattct gcctaaagga
     8641 atagttatca ttggtataca atgtcctgat tgaagattat atatagaagg tttattgact
     8701 ttatttgcaa attctattag taattctatt aaatcttttt cttcaataca atccttaaaa
     8761 tctccaaaaa ttataccatt acattcctca agctttcctg aggaatatag ttgtgttaac
     8821 attctatcca gtttatattg aggttctcca atttcctcaa taaacaaaat tttatctttt
     8881 gcatctattt catattttgt tcccattgta gcaattatta aggataaatt tcctcccatt
     8941 attattccct ctgctttacc ttcacataca gtataaattt tttcttcttt tggattttct
     9001 aaatataagt catctttaaa ttctaaagca tttaccaatg atttataggt aaattcatcc
     9061 catttagcta cattggcagc cattattcca tgatatggta aaagaccaca atttttataa
     9121 aaagctaaat ttaaacctgt tatatcagaa aaacctataa atggttttgg attttgtttt
     9181 attatctcat agtttatttt atccaatatt cttgttgttc cataacctcc tcttaaacac
     9241 ataatcatat ctacatcttt atctaaaaac atcccttcta tatctcttgc tctaatatca
     9301 tcattaccag ctaaataacc tttataactt aaactacaac tttcagaaaa cttaacttcg
     9361 taaccataac tttctaagtt aaactttatt tcctccaaac ttgtatttct taatggccca
     9421 gatggcgcaa ttattcctaa catttaaaca cctcttctta taaaatgata tattcttctc
     9481 catactaaat atctctaata taattataag atattttatt tgtacttgat acagaataat
     9541 gatttacata aaataatata attaataagg aaaaataaat ttttaatatg gttaggatgt
     9601 gttttatgct taatataaga actctttgta atgagataaa tgattgggtt ataaatataa
     9661 gaagagattt acataaaact ccagaacttg gactagaaga atttcaaact aagaaaaaaa
     9721 ttattaagta cttaaatgaa ataggtataa attatattga atataagaat catacaggga
     9781 taactgcata catcaacgta aatccaaact ttgaaacagt tgcaataaga gctgatatag
     9841 atgccttacc tataacagag gaacttaatt attcttataa atctattaat attggaaaaa
     9901 tgcatgcatg cggtcatgat gcacacactg ctattttact aggtacttgt aatatactat
     9961 ttaaattaaa ggattactta aatgtaaacg taaaattctt ttttcaacct gctgaagaaa
    10021 ctattggtgg agctcaactt atgatagaag atggatgtct taaaaaccca aatgtaaaat
    10081 atatatttgg acttcatgta aatcccaata tcaacaaaaa tctgattgaa ttaaaataca
    10141 acactctaaa tgcttctacc gatacacttc aattaactgt acatggttca aaatgtcatg
    10201 gagcttatcc acatcaaggt attgatgcta tcgttatatc tgctcatatt attacagctc
    10261 tacagacaat cgttagtcgt aacacaaatc caactgattc tgtagttatt tctctaggaa
    10321 aaattaaagg tggaatcaaa gaaaatatag tttgtgacaa agtagttata aggggtactt
    10381 tgagaacctt gactcctgaa actagagaat tttcaaaaaa acgaattaaa gaaatttgtg
    10441 attttacttg taaaacattt ggaggcagta tttccgttga aattgaggaa ggttacccag
    10501 ctcttatcaa ttcaaactat ctagtagatt acgtcaagca aaatgctgta gaattgtttg
    10561 gaaaagaaaa tattatcctt aaagacgcac ctactcttgg ggctgaagac ttttcgtatt
    10621 ttctaaaaca ttgtgaagga gctttttacc accttggttg tgcaaatcga gaaaaaaaca
    10681 ttatttcccc tctgcatacc tctacttttg atattgacga aggttgtctt attactggtg
    10741 tcatgcttca tgtaaaaaat gtattagcat tttaaatatt aatattttta tttattattt
    10801 tatattgacc ctcacatgat gtcatgttat accctaaaat tacaaatgat aaattaatta
    10861 attggaggta atattatgaa agaaatatta ataaatccta taggtaaaat acgtattcaa
    10921 ggcgaggagg tctttattaa attagacaaa aagtatgtac ctgcattaaa tgaactcgac
    10981 gacttcagcc acttaaatgt attttggtgg gctgatgggt tcgataatcc tgaactaaga
    11041 agtattttag aaactcctaa accttataaa agtgggccag atgttatagg aatatttgca
    11101 acaaggtcac ctataagacc caacccaata gcattgacta ctgtacaaat tatcagtata
    11161 gaccatgaaa atggtataat aaaaatacca tatattgatg ctaatgataa tagtcctgtt
    11221 attgacttaa agccatatac tccaagcatt gatagggttg aaaatccgtc agttccaaaa
    11281 tggtgtagtc actggcctaa gagtgtagaa aaatcaggag aatttaattg ggaagatgaa
    11341 attgaatttt aaattacttt tttcttgatt tcattaactt gttttccaca tttattttat
    11401 ttacacttac caagatttta tgtcacatat acatataata ttaggctgta ttatataata
    11461 cagcctaata ttatataata aatttctatt tttcccttaa atcattcaca ttctttctaa
    11521 gaacataaga tttttctatt atttcgtttt gagtttaatt tagcattgtg ttaaggataa
    11581 aacatttcgt gcatttttaa taaattaaat ttttctttta ctccacgatt ttataataat
    11641 caatttaaat taaaaataat acctaactat tttaactatg ttaaactagt aaatgtaacc
    11701 acttatatgt tacaatttta tataaacatc agatataaaa aactatataa ataaatgaca
    11761 catagtgtta tattttttaa taccagttta gttatttttc agttacagat ttaataataa
    11821 ttaatagtaa gacataatgt ttttatgccc tttattgatt atgtattttc tgttatctgt
    11881 tattatcatt aataataaac ataagggggt atatattatg aaattatatt taagtgctga
    11941 tatagaaggt acttgtggta ttgtaaattg ggatgagaca aaacttgaat gtgaattttc
    12001 acaacactat agaacacaaa tgagtaaaga gatagcagca gcatgtgatg gagctactca
    12061 atctggtgtg catgagatac ttgttaaaga tgcacatgat agtggtagaa atattaatcc
    12121 aaatatttta cctgaaaacg tcaaaatact taggggatgg accaaagacc cactagttat
    12181 gatggctggg attgatgaaa gctttgatgc atgtatattc actggctatc attctggagc
    12241 tacttgtaat ggtaatccac tttctcatac tatggatatt gattatgatt attttaaaat
    12301 aaatgatgaa atagcatctg aatttactat aaatgcttat attgctgcat attataatgt
    12361 tcctgtagca tttttaagtg gagatgaaat gctttgtgag agtgcaaaaa aactaaatcc
    12421 aaatatagtc actgttcctg tgtcaaaagg aattggaaat ggttcaattt caatccatcc
    12481 aaaccttgca ctaaaaagaa tcgaaaaagg tgtcaaaaaa gctttatctg gagatttatc
    12541 tagacactta ataaaattgc cagataaatt taagatagaa ataaaattta gagaacatta
    12601 taaagctttt aaggcctctt tttatccaaa tatgaaaaaa atagattctc agacagtact
    12661 atttgaaaca gaggactatt atgaattttt aagaatgtta ttatttatat aagtttcatg
    12721 tcataaatta aggggttgat taagataagt aataaaagaa ggattccttt aggcgaattt
    12781 atttctgtat ttttattttt tgctgttttt tttagtataa ctttttgtat tttcacggtt
    12841 ataggaattg gcttcttatc attcttagga tttgaatata agtctcttgg agctgtatta
    12901 attttctttt taatatattt ttgtataacc actccaattg attttctatg cactactatt
    12961 ttagatatat tcagatatgt aaacaaatta ccatattcaa tatataaact ttgcgaattt
    13021 ataattgatt ttatactaac ttttctagct atgaacataa ttgatacctt tatggattca
    13081 gtaacgattc ctttaagtac agaaatctta ttcgctttac tttcttatct tttgtccgaa
    13141 tgtatggatt tttttgataa agataagaaa aaaccttaat aaaaaagata gatttcttaa
    13201 tagaatacat attttcgtat ttctattact taatctatct ttattttatt taataaattt
    13261 ttattaatta aaatatagtt tcttctatct ctttagtcat ttgcttagca ttatcaaaaa
    13321 attcttctat atacactacc tcatcactaa ccctagagta ttctgctgca aatgccatta
    13381 catgactttg tatagcttct tttgctgcta ctctaccctt ttctagttct ttatttgaaa
    13441 ctaatttaat aaattcagct ataagatttc tatcgtattc ctctaccata ttctgttgat
    13501 ttgatggatt tataactatt tcttcatttt ttccaaatgc tttaattctt atctcatttt
    13561 tatttaaatc tccaccaact tcaccatggc taaacattaa ctttatagtt cttccatttt
    13621 ctttagtaaa tgcacataaa ttaaaagtag ccgtcactcc attttcaaac tgtaatatat
    13681 ttaccatatt atctacaaca ttattgtcgc atctataaac acatcttcca tatggacttg
    13741 tcttaagtat atccaataaa ttctctttag ttggatttat atggacagct ctatttatac
    13801 ttctatcttt ttctaaataa attctctttg ctgaatatgg acattttttt tctactaaac
    13861 actgaagaca attttgtgcc atctctccac tagcattttg gttattaaga tgctttaagc
    13921 tcccaaatgc agatattttt ttacatctac ttcctactaa atataataaa atatccatat
    13981 catgacaact cttggctaaa attaaaggac ttgtttcatt gctatttctc caattccccc
    14041 tagtaaagct atgtgcaaaa tgccaatatc ctatattttc attatattgt atactaacta
    14101 gttctcctaa ttttttactt tctacaatct cttttaattt gttataaaat ggagaatacc
    14161 tcaatacatg acaaatcata aaaagcctat ctttatactt atcacatagg tcatttatat
    14221 gtaccaaacc atctaaacta ttagacattg gcttttctaa taatacatga taaccttttt
    14281 caagagctag ttttgctaca tcataatgtc tatcatcatt tgtagctatt ataactgcat
    14341 ctgccatctt gtccttttta aaaaagtctt ctaaagtttc aaatacattt ttactatcta
    14401 ggttatattt ttgtgtaaat agttctcgtc ttcctttttt aggctctgct acagcaacta
    14461 tttcacatac atcagaattt tcataaatat atggagcata tgcatacgtt cctctattac
    14521 cagctccaat cacagcaact ttcacttttt ccatacttta atttatcccc tttatattat
    14581 ttatactact ctattatagt ctatttttac ggatatttgg atatttttaa taaaagaaac
    14641 agcagttata atttttcaat tttaactgct gttataagtt aatataccaa acatttttaa
    14701 ttaaattttc tttaatttta atacaaagac ttaaatattc aatacaaatt ataaaaacac
    14761 ttttatctag cttacttctt cttttctttg tctaatttat ctaatttctt attatataaa
    14821 aacatataaa atgctgctga aaatactatt aaatatccaa caacacttaa catatctgga
    14881 taaacattga ataagaatat acttaaaatt gctgaaaaga ttatattact gtagtcgaat
    14941 atagatattt ccttagcagg tgcatattta tatgctagag ttattccaaa ttgacctagg
    15001 cttgcaaata ctccacctag taatagatat ataagttgca taagagtcat tggttcatat
    15061 actgcaaaag caattggccc tacagtaact aatgaaaaaa ccgaaaagaa aaatacgatt
    15121 gtatagtaat cttctctatc tccaagaact cttaaacaag tatatgccat tgctgcaaat
    15181 acagctcctg caattcctcc aagatatgga attacttcta cactaaatgt tggttttatt
    15241 atgaataaag ctcctataaa tgcaattata atagctccta tctgctttac atttattttt
    15301 tcttttaaag caattgcaca aaatataact acaaggaaag gactcatttt atttagcata
    15361 ttagcgtctg aaagcatcaa cttgtcaatt gcatagtagt taaatataac tcctagagtt
    15421 ccaaatattg acctatataa aagtactttt aaattttctt ttttcccagt tagactacct
    15481 ttatgtttta tgataagcca aaaagctatt atagctgata ccagatttct aaagaacact
    15541 ttttgaaaac ttggtaaatc tccagctagt tttacaaatg cagacatcat tgcaaagcca
    15601 agagctgatg ctattataaa cattatacct tttattcgat ttgatttgat tgtgctactc
    15661 atacgtacct cttttctata taaatgtata aagccgtatt aattaaaaac ttagcttgta
    15721 cattaaataa taattatcta aatattccaa tttatactat aattaaaagt gtaaactatg
    15781 tcaagtaact aataaatctt ttcaattaat aacaataata attatagtta aaaagttata
    15841 tgtttttatg gattattatc agaatatata atataatttt atatagtata gacttttttt
    15901 aatttattat ttagattttt aatagatttt ttaactatgg aggtatttaa aatatggaaa
    15961 taaagagata tgaaggaact ggaagaatga gtagagctgt agttcataac aatacagttt
    16021 atttatgtgg acaaactcat gctgaaggag gagtaattga acaaacaact gaaattttgg
    16081 ctaaaataga agatttatta aacaaatatg gttcagataa gcaacattta ctatctgtta
    16141 ctatttattt aagagatatg aaagactttg aagctatgaa ctctgtttgg gatgcttggg
    16201 ttgaaaaagg atttgaacct gctagagctt gtgttgaagc tagacttgct agagagcatt
    16261 tgttagttga aatgagcgtt gttgcagcta caaaataatc aatttagctt ataggggggg
    16321 ctgtctcaaa atagagagat aagcctcttt tttattgttg aaatgatgaa aatatattcg
    16381 atttcatata aaagaaagtg cctcacgaac caaaaagttc attttgagac acctcctcac
    16441 tatttaatct atataaattt acttattctc tattggcaat atcaatttag atggatattt
    16501 acctccatga taaatcgtat tctttgcttc tatatattca atactattat atccctctgt
    16561 cgtgttacta ttttggaaaa taaagttttt agcactagat gttatgtcta gtctaatttt
    16621 atgaccaact ttaaacgtgt ttgatatttt tgaagttata atcgtaaatt tataaatttt
    16681 tccttcttcc ataaactctg actcataaaa accatttcta aatctagcac taagtatacc
    16741 atcagctaat ttaattgaat ttccatctaa atctacgtcc ataattttta taacccagtc
    16801 agtatctctg gcagaacttg atgcgaaaaa ttctaacttt atatcacctg ttatagtaaa
    16861 ttcttcacta aaaacatctg atgtataaca caacatgtca cttctttttt ctaaatcttt
    16921 gtagttattt ggaactccaa cttcattctc tgacatatca attagttgta ttgatgggtc
    16981 ttttggatta tatatataac tatcacactt ttcttctaac ctactatcaa atactaatct
    17041 accatttcct aaagatgtgt tagcatttcc atcacttatt aaatacatac tcttatctat
    17101 cttgtttatt attggccaat tttcttctgt cttccatata ttagaaccta cagagtaata
    17161 ctctattgga gcagttgtat ctatgttatt ttctatacct tttaagtatt tatcaaacca
    17221 taacagataa ttataatcta aatcatatct taatgaacta tttcctaaag aaataccatt
    17281 tatatctctt aaagtatttg aattatgcat ccatggacct agaatagcct ttctctttcc
    17341 tttttcatag tcttttataa catctaaggc ctctgtagtt cccataccat tatcatcata
    17401 ccacccagat acaaccaacg caggtacatt tattttatct ttctgtaaat gccaatccat
    17461 caaatcccaa tactcatctt tttctactct ctttaaccat tcttctagaa attcaattct
    17521 atacccaaga gcttcaacag gtatattctc tattggtcgt atgtttaaaa catcatccca
    17581 atcatctctt accattttac ttctatcaac tttatttctt gataccataa acgcccatgc
    17641 aagcatacca gatacgaaag ctcctccttt tcttggtatg tcaataaaag ggcttcctga
    17701 tgttactata ctaactaaag ctttaagatg cttattacct gaagatgcag ctgcccactg
    17761 aacatagcca agatatgatg ctccaagcat tccaactgtt ccatctgacc attcctgtga
    17821 tactatccag tttatagtac tatctccatc ttctctttca tgaatcatag gtttccactt
    17881 accttctgat tcgtttcttc ctctaacatc ctgtattaca acagcatatc ctctttgtac
    17941 atatttataa tatatttctt tatcattttc ttttccatat ggagttctca taagaattgt
    18001 tggtgctttt ttggtagaat ctataaaatt agggagatat acatctgtag aaagttttat
    18061 accatctttc atatcaatca tataatttcc accaaatctt atagaatata tctcttcatc
    18121 tttatgagtt ttatcccatt cttttaatac agtatactct tcatatccat ccataattaa
    18181 tatagtacaa gtttctctgg ataaacaaat aaaacctact attttattat ctacaataat
    18241 tatatctagt gggaactttt tatttctttg aacccatata tattcattaa gtttagaatg
    18301 cgtttctcct aagttattta taactgtgtc tttatctgtg tttactaaac ttttagtata
    18361 tacatcaaag ttattaaata aagactttaa atctattttt gtaagattta aatagtatgt
    18421 attttcttct ctgcttattg gttttaaact ttctatttta tttgtaaaag gattcaactt
    18481 ttcaattaat aaatcgtcat caaagattac atttccactg tatagtccag atatgtataa
    18541 tttaaatttt atcaattaaa ttccccccta taatcccaga gacatcttta ttgcatatgc
    18601 cactgatata cctgcataat ttcctaatac tccaccaatt actcccatta caactgctac
    18661 acttacaagt gaattccatt ttgcagaagc agctactaaa gctgaagtag gaccatcagc
    18721 aattgctcct actatagaaa gtattacata ttgatatttt atctttaaaa gtctagttat
    18781 gcctaaatgg aacacaaaag aagtaaaaat tatgctaaaa cagtaaagtg ttatagtaaa
    18841 agttgaacct aaaaactctt ttatatctac tgaaaaacct attgtacata aaaagaataa
    18901 tgcaacaaat aaccctaaat ctaaatttcc ctttagtttc tttactggct ttaattgagc
    18961 aattataatt gaaattgttg taactaaaag tattcttgct gcactactaa agcttgaatt
    19021 gaaatatcca gcaagtattg ttgagacctc tgtaacaaca aaacctatag ccaacatcca
    19081 agcgatatct ttaatactcc actcttttga ctccataaat tcttcatttt gacaatcttc
    19141 taattctgat tcttctacat gatatggcca aagtttttta aacttctttg agttttttaa
    19201 tatggctggt agagcaaaca taaatatcaa tgttggtact ccaattacat agtctgctgc
    19261 atttgccgca gcaagagttt gtctacttac attaagacct gttccaatgg ctgtaagatt
    19321 agcacttcca ccagtgtatg tacctacaaa cattccagca actttccaac cttctgatat
    19381 tttttctgca aatactagcc caaataaaaa tgccatgata cttacagtta atactgctac
    19441 aaaaattgca atcaaaggtt ctcttgataa ctttgtcatt tcttttaaat caacactcat
    19501 caacattata gtcatagaaa ctggaatcgc atatgttgaa atagttccat ataattcagt
    19561 acttactgga actactttta agtttgaaag tattattccc attatgatta ttgtaagtgc
    19621 tggtcctaag cttttaatgg ctttgtatct ttgtaagtaa aaacccaatg caatcattaa
    19681 tgtcattaca gcaagtatac tacctggatt tgaaaaaagt gtattcatat ttaacctcca
    19741 attttatcat aagtttactt ctattcctaa acctggttta ttgagaagat tcataatatc
    19801 tccatccatt acaaatcctc cagatatact ttttgattct tcacaaaaca taaagctatc
    19861 aaggtcagct tctgttatat tctttttaga tgctattaaa tttgctgctg ctgttatacc
    19921 aattctcgtt tctagcatac atcctaacat acaatttact ccacttgcct cagctatgtt
    19981 gttgattttt atagcaggat atattccact tgacttcatc aacttaatat taaatgtatc
    20041 aactgcattc ttttttatag ctttaattgc atctattggt gaatgcaatg attcatctat
    20101 cataatcttt atattactct tatttcttat gtaagcagta ccatctaaat cccagtgtgg
    20161 aagtgcttgt tcaattgcat caacattaaa ttcttccaat tttttgatag tatttatact
    20221 gctatttacg ttccatcctt gatttgcatc aattctaatt cttatactct ctccaacagc
    20281 ttctctaatt aactttacag cttcaatatc atcttcagga tttatacctg ctttaagctt
    20341 taatatccta aaaccttctt ttactctttc taaagcttct attgccattt tttctggctt
    20401 atctatactt atagtaatat ctgtttggac tttactatca aaacctccaa gaactttata
    20461 aagaggtaca ttcataattt ttcctttaat atcatataaa gctatatcaa tagctgcttt
    20521 tgcagaagta ttgcctataa taattccatc catgattgta tgtatggttt caatatctag
    20581 tgggtcttta cctattaact cttttttaaa cataagtaat accgaaataa cattgtccaa
    20641 aacttcacct gtaactgctg caagaggtgc tgcttctcca aatccacaat agccttcatc
    20701 agtttcaatt tttaaaatta tactttctcc atattcaatt actccaaatg aaactactac
    20761 aggttttttt aatttaattc tcagcttttc aaatttgata tctgttatct tcatattacc
    20821 ctccttattt ttgaagttat aattcaattt ttaaaatttt atactttaaa ttatattatt
    20881 acttcaatat atatgtcaag ataatttact gaaaatttac gcttttccaa aatataatgt
    20941 aataatatta attcaattaa cactcttcca ttaaattttt ttattattat tctctttatg
    21001 ttaatttagc aataatttat tttcatagac ttttctttgc ctttaattaa attttaattg
    21061 tcaaaatcta ctaagtattc ttattgccac tacttctatg ttatgctata attactttgt
    21121 tttaagcgaa tattttatat taattttatt atttggaggt tcttatgcta ggtgaaaaga
    21181 tgagaaatat aagaaaaagt aagaaaaaaa cattaagtga tgtttccaaa ttgacagatt
    21241 tatctataag ttatatctct caaatagaaa gagatgctat tgaaccatcc ttatcttcat
    21301 tgagaaaaat cgctgaagtt ttagacactc ctttatatat gtttatggat gataacaata
    21361 ctgatgattt agtcattaga aaagaagata gagttatgat gaaatttcca aagagtgaaa
    21421 tgttttacga gatagtatct ccaatgccta cacctgagtt tacaccttca attttatttg
    21481 tagagtttga acttaaacca gaaagcgagg atgccaaaga ttatatctat catgcatcag
    21541 aagaaatcat ggtggtaaca agtggtgtgg tggatgtttg tatgggcgaa aagatagtga
    21601 gattaaatcc aggtgactca acatttataa aagctaatgt accacataaa atcatcaacc
    21661 caagtaagga tacaatagct cgtggatatg gagttatatc acctccaatt tggccaataa
    21721 aatctaaata aattcaataa acatatctac tttttataga tactacaata gatttaaata
    21781 tcacttttat tttaaaattg aagtatttat ttaaatttaa catatttaat caaactaaaa
    21841 aaatagctat ttgactaatc taaaccatct taattatggt aaatagtaaa tagctatttg
    21901 taagttatat tttaaattat aataaaaatt atatttatta aaattaaatt aaactgctat
    21961 atcatttaat acttttgctt ttacaactct tatattcttc atgctcttgt agatatcttg
    22021 aatcttatct tcttgttctc tcaatagtct atgtgcttca tatatatcca caagttcaaa
    22081 ttttactaca tcattcggct ttgcttgtgc taacttatat aaatctacac ttataacgtt
    22141 tcctatctta gtataaccac cactagtctg tctatctgat aacattataa taggttttcc
    22201 atgaccaggt acttgtatag ctccataaga gataccatca gatataatat ctgctccatt
    22261 aatgtgcttt atactctctc catctagtct acatcccatt ctatctattt cattcgtaac
    22321 tttgtattca tttgataaaa atttttctac ttcaccttta gaaaaagcat caaattgagg
    22381 accttttaca attcttagta cgatttctga gctataagtt ggaatatatt ttgaatttaa
    22441 ttttttattt attgtaaaat ctttttcctg aataaaagta cttatataat ctcctttttt
    22501 aagtgctcta ccttcaaacc caccaatttt agctcttgta taagttgact tactccccat
    22561 tgcaagtgga acatctattc caccagagat tgatacgtag gctctagcac ctgatttcac
    22621 acctctaaat gataatacat cacctggatt tatttgatat gacctccagt tttgaatttc
    22681 ttttccgttt attttagccc ctaaatctcc cccagttact gctatttgcg tatattcatc
    22741 aaaggtaatt gtagggccta acattaaaac ttctaaagaa gcctcatctt cagaatttcc
    22801 tactaatata tttcctactc tatgtgcata ctcatccatt gctccacatc cagatacacc
    22861 atattgacca tatccaactc tacctctgtc ttgtattaat gtttggaaac ctcctaattc
    22921 aactttgaat cccatatata ccactccctg tactataacg atatttaaat acttaagtta
    22981 tttttttcga tttctataaa ttcatctaat gttattggaa caaattttat aaagtctcca
    23041 gctctaagca aaatctgttc ttctctattt tcatcatata attttaaagg tgttctacca
    23101 attatttgcc atccaccagg actatcgata ggatatacac cagtctgaga acctgctatt
    23161 ccaacactcc caccataaat tttggttctt ggtatttcta atctaggtgt agctattctt
    23221 tcatccatac cacctagata tggaaatcca ggagtaaacc ctagcatata tatcaagtat
    23281 tctctacttg tgtgtatttt tataacttca tctacagtga gattattgta acttgcaaca
    23341 tttttaatat ctataccaaa aacctcatca tagcatactg gaatctcatg tattttaggt
    23401 tttggtaata ctatactttc caaattatct tctatttttt ttaaactctc aatcaaacta
    23461 tcaaaatcta tttttagtgg attataactt atcataagtg acctatatgt tggcaccatt
    23521 tctgttacaa tacctttaag atttgatatt tctattgctc tcataaatga aattactttt
    23581 ttgtttatat cttctgatat ctcatttcca aattcagcaa ccactgcctt atcccctgat
    23641 atcaagtatc tagtttccat aaatgtcacc tcttctaaat taagcaaata aagcacctag
    23701 gctgctaaga gaagttattc ctgtatatgc agatattaaa actactatta gtccaaatat
    23761 taagagccat gtaggatgct tgtaatctcc aacaatatct tttctcttag atgctataag
    23821 cataattcct aatgtgattg gaagtatcaa tccatttaaa gcccctgcta aaattaataa
    23881 agtagctggt tttcctataa atgccattat aagtgttgat attgctataa atgctattat
    23941 gaaatatttt tcatatttat ctataaaagg atttagtgtc tttaagaaag aaactgatgt
    24001 ataggcagct cctatgactg atgtaattgc agcagaccat aatacaagcc caaagaattt
    24061 atatcctatt gctcctgcac taaatttaaa agctgaagca gctggatttt ctgggtcaag
    24121 ttgaagacct tttgaaacta ctgctagtat tgctaaaaat aaaagaactc tcatcattgt
    24181 ggcaactaat atacccaaaa gagaagattt agttatttct tttatatttt cttctcctgt
    24241 tattccacca tctattaatc tatgtcctcc agcaaaagtt atataacctc caacacttcc
    24301 tccaagtaga gttattattg ggaatatcaa tccttttgga ttttctggtt ttaccattct
    24361 agaaactgcc tctccaacag gaggatgatt tgatattgct acatatccaa ctataattat
    24421 cattcctaat gctaaaaatt tagttatctt atctactaga gaatttgaat tttttgacat
    24481 aaatacaaat atagctatta atccacttaa tacagttcct aatgtcatat tcatattaaa
    24541 cattacattc ataccaagtg cagctccacc aacatttcct atattaaaag ctaatcctcc
    24601 aagagctact aaaaaagcta ctaaatagcc taatccaggt attattttat ttgctatatc
    24661 ttgacctcta agtcctgata caccaattac tctccataca tttacttgag cccctataaa
    24721 aaggattgtt gtaattaaaa ttacaaatga aaaattcggt ccaaaatctt gagtaaattg
    24781 tgcagtctga gttaaaaatc ctggcccaat tgctgatgtt gccattataa atgcagcccc
    24841 tataagcgct ccaacatctt ttttattttt agttttatct gtaatatttt ttgtactcat
    24901 attttatctc cccctcatgt tatcagtctt atactatgtt ctctgatgaa caaacttcta
    24961 tgttttctaa tggacaaact tctatacttt ctaattcaaa acgctttctt atttctttaa
    25021 caaactctat tgcttttgga ttgtccccat gtacacatat agaatctgct ttgatatgta
    25081 taacttcacc tgttaaagtt tctacagttc cttcttttac catcctaaca accctatcta
    25141 ttgcatgttt tgtatcatgt ataactgctc cttctgcatt tcttggaact aaaaaaccat
    25201 tattatcata agctctatct gcaaatactt catttgcaaa cctaagtcca atttctttag
    25261 cagaatttat catttcacta ttatatagcc ccaacaatat aatatcttta ttgacttcat
    25321 atatagcttc acaaatcccc atagccaact ctttatcttt agctgccata ttgtataatg
    25381 ctccatgtgg tttcacatgt tgtatattac atccatttga acttgcaaat gccattaaag
    25441 cacctaattg atattttgta taatctttag cttcctgctt cgttattttc atctcacgtc
    25501 ttccaaatcc tattaaatct agaaaacctg gatgtgctcc tattttcact ccattttttt
    25561 tagctagctg tactgttttt tccatatgac tagggtcacc tgcatgaaac ccacaagcta
    25621 tattggctga tgaaatatat tttaaaactt cttcatctaa accaatctta tacgttccaa
    25681 aactttctcc taaatcacta tttaaatcta ctttatacaa tttatgaccc cccttgctaa
    25741 cattttgata gaataagtag tttcaatttt taaattttgt ttattttata tattgcatga
    25801 aatattttat tacttgtatt caattttatt tttgcaacta ttctattgca tttaattaat
    25861 ataattttac catttaagga atatttttgc aattatttta atcaaacatt catttgtatt
    25921 tctttttcaa aaaatgtttt taccattttt tagttaacat ttaattattt tcacttaaaa
    25981 caaaggcttt aaccttcatt tttaaagtat ttttcatttt taatcacttt atatgcaaga
    26041 cagaatcatt tttcttcatt catttgtttg tttcatctat ataattatca ttctttgtaa
    26101 ataaaatatc tttatatttt tataattaat tctttatata gttttaagta taataaaatc
    26161 atgtatacta aatgcatgtt aaaatattat tttaaaacat gcacaatatt tgtacatatt
    26221 gtagacatat aaacctataa attatacaat agtattgtta agattatata attttttaac
    26281 ataaattttg tattggggga aaaacaatgg ataaaaacta tacgatgcca atataccaaa
    26341 aaatagcgtt ggatattgca aataaaatat acacgggtga aatacaagag gattcagtat
    26401 tatttggacg ctctgttttg gctggtaaat acaatgtatc tccagaaacg ataagaagag
    26461 ctgtcaaaat tttagaggac attggcgttg ttaaaagcat aaagggtaaa ggtgttattg
    26521 tactatctcc agacaaagct tcttctttta taaaaaaata tagagatatt acaaatatat
    26581 catcatataa atcaacactt tataatttaa tagatactaa atctaattta gaaaatgaaa
    26641 tattagatac tataaataaa attttagact actctaacag acttgaaata atcaatcctt
    26701 tagtgcccgt tcagttcacc ataaattcta attgcaaata tattggtcaa acagctgcaa
    26761 aaactaaatt ttggcaaaat acaggtgcta caatagttgc aattaaaaga ggtgaagaac
    26821 ttataatatc tcctggaccg tatattgaat ttctagaagg agatattctc ttagttgttg
    26881 gtgaccaaca tatttacaac tctataccaa tgtttttata tgaaaatgaa aagtaaatta
    26941 tataatttag tatgattata taaaaataca aaattaacaa aaaaagagct tcatatttta
    27001 cataaagctc tttttaaatt caaataaatt taaccttgat taatttttaa atatccaatt
    27061 catcttcttt ttcccagctt aaagctcttg atacagcttt tttccagcct ttatataatt
    27121 tacatctctt ctcttcactc atatttggat taaactcttt ttctacttgc cactttgaag
    27181 taatttcatt tctttcaata taaaatccaa cagacaatcc tgctaaataa gcagctccta
    27241 aagctgtagt ttctactatt tttggtctgt ctatatttac atttaatata tctgactgaa
    27301 attgcattaa gaaattatta ttacttgctc caccatcaac ttttaatgac tttaatttta
    27361 attttgaatc attttgcatt gcttctaaaa catcctttgt ctgataagca attgactcca
    27421 atgtagctct tactatatgt tctttttttg ctcctcttgt aagacctaaa attgaacctc
    27481 tagcatacat atcccaataa ggagctccaa ggcctgtaaa tgctggaact acatatacac
    27541 cattagtatc ctctactcta tttgcataca tttcactatc ttttgcagat tcgattatct
    27601 ttaattcatc tctaagccat tgaattgatg ctcctccaat aaatatactt ccttctaatg
    27661 cgtatgttac ttttccatca accccccaag caattgttgt aagtaaccca tgcttagatt
    27721 taactatgtt actgcctgta ttcataagta agaaacaacc tgttccataa gtattttttg
    27781 cagtaccttc ttcaacacaa ttttgaccaa acaatgctgc ttgttggtct ccagcacatc
    27841 cagcaatagg tattttagct cctgataaca tgcgctcatc tgtatgacca taaacataac
    27901 tagatggttt tactaatggt aacatgctta ttggtatatc caattctcgt aatatatcct
    27961 tatcccattc taaatcattt atattgtaca tcattgttct agatgcattt gagtaatctg
    28021 ttacatgtac tttcccacga gttaagttcc atattaacca tgtatctata gttccaaata
    28081 ataactctcc ttgttcagct ttttccctag ctccttctac attatctagt atccatttta
    28141 cttttgttgc tgaaaagtat gcatctatca aaagacctgt tttttctttt attgattctt
    28201 ccaatccttt atttttaagt tcatcacata tttctgatgt tctcctacac tgccatacta
    28261 ttgcattata aattggtttc ccagtatacc tactccaaac aactgtagtc tctctttggt
    28321 tagttattcc tattgaagca atttcttctg gtcttatacc tgctgtttct ataacttctc
    28381 tcattactcc actttgtgaa ccccatattt ccatagggtc atgctctacc catccagctt
    28441 ttggataaat ttgattgaac tctttttgtg caatttttac tatttcgcct tttttattaa
    28501 atagtatagc tcttgaactg gttgttcctt ggtctaatgc cattatatac ttcttttcca
    28561 tcatcatatt ctccttatca tataaatatt taatttatta aaaagaaaat ttaacattgt
    28621 atatttcaat aaataatcat acttaagtac aaatttaata caatagataa tttataagaa
    28681 gacacttatt ttctatcata tctacataat aatattatac attatagctt acatattgat
    28741 taataaattt taaaggagta taataaacag tgttcataat atttttaatg aaagaggtgg
    28801 taatatgcca aagattttag aaaatgtaaa agaagatata ttaaaagtat ctcgagatat
    28861 gattttagaa gaagattact cgaatattag cataaggaaa atagctcaga ggtgtggtat
    28921 aagcgcaggt acagtgtata attactttaa ctcaaaacaa gaaataatag aatacattac
    28981 aaaatctgaa tgggatttat taataaggcg aattgaatac tcaaataaaa atactgaaga
    29041 ttacatcaaa aaactagaca ttatttttac tgaaataaga aattttataa acaaagttca
    29101 taatgtacaa tacaatgact ttttaaatac ttttgaaaca gagagatttt ttgaaatgaa
    29161 aaaacacaag gatgactttc atgaacagct ttcaaataaa gtatatgaag ctttagaaaa
    29221 agaaagcttt tttaataacg ataaattagt atgcaatatc ataataaaaa tgtttttttc
    29281 atattcaaca tatcttcata tagaatttga agatttaaaa ccctatattg aaaaattaat
    29341 acattaaggt ggtgtttacc ttgaattcta atactagtat taagaacaag gacagtaatc
    29401 caaaaatatt tttagtactt acactttatc tattaggtat atttatggga gctattgata
    29461 ctggaatagt atcaccagca agaacaatta tacaaaatag ccttggagta aatgaaaaaa
    29521 caggaatttg gatgattacc atatacacat taacatatgc ttctgtaatt cctatctctg
    29581 gaaaattagc agataaaata ggaagaaaat atgtgtatct agttagtata tttctatttg
    29641 gtagtggttc attaatatgt ggattatcat cactattttc caacttctat attttactaa
    29701 tcggtcgtgt tattcaagca attggtggtg gtggaattat gccgattgct acagcagaat
    29761 ttggaactac cttcccagaa aataaaagag gtatggcttt aggtttagtt ggagcaacat
    29821 atggtattgc caatatttta ggttcaagta ttggtagcac aattctaagc atatttggaa
    29881 ctcaaaattg gaagtggcta ttttttgtaa atctcccaat ctgtttaatc atacttattg
    29941 gtggagtttt ctgtattaaa aacaataaat ctgaatctaa agaaaaaata gataagcttg
    30001 gtacattaat gttggtatgt ataatcgtat cactattata tggtcttatg aatatagact
    30061 tttttaattt taaaaattct atacaagata tatcagttta tccatactta ttgacattta
    30121 ttgtacttat acctattttc atatttattg aaaatagagc taaagaccct attttaagct
    30181 ttgaatattt tttaaatcca agaatattga taatacttat tttatcttta attgttggta
    30241 ttggaatgat gggtatggta ttcgttccac aatatgctga aaatgcatta aagataaatg
    30301 ctggttctgg tggatatttt gtagctatac taggattatt tgcaggtgtt gctgctcctt
    30361 taagcggaag acttattgat aagtttggag caaagaaaat actattacta ggattttctg
    30421 tgtctatgat aggttctctt tatctagtct taattgctct aaaaaccaat acagtattca
    30481 gtgtatgtct aagtctaatg tttatgggat taggtatggg atttactatg ggaacacctc
    30541 taaactacat gatgttatca aatacaagat tagaagaatc taattcagca cttgcaacat
    30601 tatccttgat acgctcaatt ggtacttcaa tttctcccgc tataatgatt ggatttatag
    30661 cacatgcagg attatctgta caagataata ttatggactt agttggaaaa ccctcaacgc
    30721 ctaaaatagt tcaacttgaa gaacttgaaa acatgataga tgacttaaaa tcagaccctg
    30781 aaatggcaaa aaatttaaaa aatgtctcta ttccaaatat gaatgatact tcaaatataa
    30841 atatggacat gacaggtggc aaacttccaa aatacttact tgataaagtt caatcagcag
    30901 atacaaccaa cattacaaat ataacaaaag aaatatcaac aacaatgttt gatgaaaaag
    30961 ttccatctat aatttctaaa atacagaaaa atgtacaaaa aggaatagat ggaacacaaa
    31021 gtggaataaa cggtattgaa gaaggtgaaa gtaaactaaa tagtggtatt aaaggagttc
    31081 aaactggtat cgacaacatg gtaaaagcta gagctggtat caatcaagga atagatggtg
    31141 taaaaaaagg tattgctggt attgacaaag gtataaaagg gatggaacaa ggtcttaaaa
    31201 agcaagataa agctattgat gaacttacaa ctgcttacaa taaaatacct actacagaaa
    31261 aaattcctac taataatgaa aataactcaa atgaacaaaa ccaagataat gccagtaatt
    31321 ctgaatcaga cgcaactaat aatgattcca cagaaaataa aaataacaat tccaatgaca
    31381 ataaaccaaa tttaaatgaa caaaaagaaa gtttaaatgc tcaaatacag aaattaaaaa
    31441 agacaagaaa tgaattaaat gcaaagttac aaaaaaataa agctcaaaag aatgaattaa
    31501 gtaaaaaact aaaatcaatg gaatctcaga agaaagaact acaaagtaag ttaaataatt
    31561 ctataaacca aaagaaagac atggaaaaaa gccttgatac aatgcaacag caaaaaaaat
    31621 cactacaagc agttttagaa aaaacacagg aggtaaaaac tgaaatacca aaggcttttg
    31681 ataaatcaaa attggattat ataaattcca tagaaaataa tagaacaaaa atagagaata
    31741 cactacaatc tactctaaac tcaggattta aacagatgta tataacagta ttctgtgtaa
    31801 atctactagc attcgtaata ttattgttct ataaagaaaa taaaactaga taaaagagtg
    31861 ttatagtatt atattgtaaa tctatcttat tcttaaatat tttatcctaa agaataaatg
    31921 cataaaaatt tttgtaatgg attaatataa attacaatat aatactattt ttctattaat
    31981 cttttttact attaaaggaa tcaaaaggta tcttagctta tctaaataaa tttatacaat
    32041 ctattcatac acacctttac atttttataa caattaaact tattgttata tacaaatcaa
    32101 aataaaccat atattttcaa ctataatatg ttaaaatcat attatgagca tattaattta
    32161 agcaaaatgt catttagact ttaatttagt agttttatat tacaattttt tatattttta
    32221 attttaaatg tcatttagac attatttata aaaagaaagg agtgtatttt gtggatactt
    32281 taggaaaaag aattgcttat ttaagaaact ccaaaaaact tactcagcgc aaacttatgg
    32341 atattttaaa atttgaaaac ttaggcaagt atgaaacagg agatagaaaa cctaattgcg
    32401 atatagtaat gtcaatagct gattatttta atgttacgac tgactggctt ctctatggta
    32461 aagaaaaagt aaattccaat aatagtgtaa aagaagataa agaagattac ttacatatta
    32521 ataatgatga aatgactata ttaaatctat atagacaatt aaacgaacgt gataaaataa
    32581 aaatagaagg aatacttgaa cttaagatat ctgaatacaa agacttaaaa aagcattcct
    32641 ctaataataa tgaagataaa atggtttaaa catacataat ttgatacgat tttacatcat
    32701 ctattaactt tcttttttgg tagtatatta ctaaaatatg gatattggat tatttaaaaa
    32761 caagtatagt ctaatttcaa gcacatttat aatatttaga ttatcttatc catattttag
    32821 tttacgtact ttgaaaaata taatacattt ctatgtataa tttatattcc taagaaatgt
    32881 attgctcatg tttttaattc ttccaacatc tttctatata caattgtaca tccttcataa
    32941 ttcccctctt taagaaggat tgaacatgta ctagaatatt tagtcaaaat atttaacctt
    33001 tccatattta agctttttat attactaagt gctgtaataa aatcatcaat tgctttacaa
    33061 cactctataa ctccatctga atccaattta cacacaagaa tattcaccta ctttatatac
    33121 tatttattaa tcatcttctg aatattctat attaagcaat tgataaattg atgatttata
    33181 ttttttacct gttcttctcc catttaaaat agctgacaaa tagttttcat taacacctat
    33241 tttcttcgct aattctcttt gagtcatatt taattcaata agcctttgct tgacttgtac
    33301 tcccaaaaaa ggtatccatt ttcttcgagc atccatttat caacttcctt tctaagtaat
    33361 ttatatttac ttttatattt tagtttacgc accccctcta tttagtatat atttttaata
    33421 tgtacacata ttaagtatat aaatttattt aatactaaat aagatttttt gattactttg
    33481 tgctaaaatt aggatgtaaa ttcgtatcat taagttaatt ataaagtcat tttgacctta
    33541 agtcaatgat ttttatgtca ttttgacctt tattttaaaa ctatttatgt cttaaaaagt
    33601 ctttttgaca ttaattgaat ggagagtgtt tatggatact ttaggagaaa gaattgttta
    33661 tttgagaaaa gcaaaaaacc ttaaacaata tgaactagaa gaaatgttgg gctgtgacaa
    33721 cttgagtaaa tttgagagaa acattagaaa accaaattat gaaatattaa aatctatatc
    33781 tgagatattt aatgtttcag tagactggct attaaatgga gataatctat cacataaatc
    33841 agatttaatt tgcgattcct cctcaaacta tccacttaat agcataaact ctaatgaaat
    33901 aaaactttta aacaacttta gaaaattaaa tgattatgac aaagccaaaa tagaaggtat
    33961 gattgaatta aaacttcatg aatatgaaaa agataagaat ttaaaaaaaa ctgagtataa
    34021 taaaactaaa gatgagaaaa tagataaata atatttatgt tgcttttgat acgattttac
    34081 atcatttctt tgttctaata tttttatttc atttattttc ttttttataa ttttatgata
    34141 aaataattag tatattttgc tttacttgaa tgtaattatt tatacaaaag tcaaacataa
    34201 tataaatgta gtaaattttt agtttcaagt aatatctcgt tattataact aaatatttat
    34261 taaaattagg aggataaaat gggcttaaga gacaaattcg cgcaatcatt tgctagatca
    34321 aaaactatga gtggccctga gaaaaaggct aatgaaataa tgggtaaatt gcttcttaag
    34381 aaagctatat tacctatcgt tttaatgttc gtgataataa tcgctggagc tatgcttaaa
    34441 atcaattctt gggttacact tggcataaat ttagttattg ctgttggtgc tttcttctac
    34501 ataagaaatt ctagtaaaaa gtatcagaac tttaaacctt atgttggcaa tttgattagt
    34561 ttagagaaaa aaggtaaaaa agagtacgtt gctattataa aacaaggtaa gttaccagtt
    34621 aagttacaaa ttgcttatgg tggtgaagac cttgaacatg ttaagaaaaa tcaaatggtt
    34681 cagataagtt ataacccaga tgctaaaata gctattttgg ttaatagaca ataatttaat
    34741 aaaaaaagga gttgtcttaa aattgatttt ttctaatcaa atttaagctc aactcctttt
    34801 tgaattttta tatattattt ttattacttt ttttaattaa tattttaaaa tattaaatcc
    34861 ttctcaataa aatagggtac tatctacaat actactttat catttcccaa caatatataa
    34921 tctggtgcta ctgctacgtt catgttatac accgttttgt aacatacctt ttatatcagt
    34981 aacatcttcc ttaatttcct ctacatctgt tttcattatt cccatttgaa caagtatatt
    35041 cttatttatt tcttgttgtt gtgtagataa ttctataaaa ttttctacag tttttttata
    35101 catgtctcta tcttcttttt tctcttgcat agtattttta aataatagag cacatagtat
    35161 gccgattgcc cctagactac tcaattcggt tattaattta tccattatag cctcctattg
    35221 tccaattttt ttataattat aactttaatt tttgttacat tcttacatca tgcaatatta
    35281 tattttcagg attatcaatt taatcttttg tattttaaat tgtaggtgta atttatagat
    35341 tgaataaata ataaatatat atacaatttc taatataaca aaaaataagt acaaggctta
    35401 cttattaaag ttaagacctt gtactttaca taaaaaaaat aactaataca tagttattct
    35461 aaatttacta ttcaactggt atttctaatt ctttacatct aattctaact tgctctctaa
    35521 ttactgctgg tacttcttct attgtttttt tgcctcttaa aattaaagct acatatactt
    35581 ctaccattcc actctcacct ccagattttc ttacactaaa agtgcttata ttacttgctt
    35641 cattgacaga actttgactt aacaacatct catatatttc cgcatttgct ataaaattat
    35701 ttgttatatc atcatcttgc tttacttgac ctatacttat gtctgagata tctttattct
    35761 gcatttctac ttttctacct tgtttgattt gttctatttt atttttatcg aatttaaaca
    35821 attttcacac ctccatttta agcttgtggc tcgttgtttt cagcatcata tctaaaaatc
    35881 atagatggac gttttatagc tgtccattta tctccttttt ctactatgat tttaggctga
    35941 gcacttttta tgttggcttc ttctaattca tagatttctt ggtaacttga gtctgatttt
    36001 ttgatttcaa ctagtttcat gtctttgaat aagtcagatt tatttatttt tacttgaact
    36061 ttagttttat ttattaattg atatataggg tctccaagat ttaaatcttc ttcaagccct
    36121 ctatctagtg taattgtaat atcttgttca ttagatgttg tattaactac cttgtacatt
    36181 ctattaccta tcataacata agaatcttta attatagaat ttccagtact ctctttaaaa
    36241 ataaataaag atgcatataa atcatcacct ttacaataag ctctaaatag tatcttattc
    36301 tctcctattt taattttatc tggtggtact tcaaatgata ttttttcagt agttaaatca
    36361 cttacagatt ttacactttc accatttata agcatttcta ttctacttat atctttatta
    36421 gggtcttgta tttttatctt aattgatgaa attgattttt cagtaatttc tatagcagca
    36481 tttgtcgttc ctacttctga tataatatat aatgtattgt ctgttgcaag tacatccttt
    36541 actgtattta catcttcaga aataggtact atagtaaatt cttttaaaaa ttctactggt
    36601 tgttcaattt tatatacatc cctatttttt ccagtaaccc atactgaatt atcattttta
    36661 agcaccaata tatggtcact tccataagat tttatttctc ttatgtctgt taatgctttt
    36721 gtaaagaatt ttataatagc attttcatta tcgcttccta accctaaagc tcccttatca
    36781 ttatatcctt gtacaaataa ttcattacct gtagttacta ctaatgtata gtttttacca
    36841 caatgtactt ctttacaact agatacagtt gtaattcttt gtaattcagt aactggatta
    36901 ttgtgaccta tacctaattg gtattcagag tttttaccaa tagaccaaag actatcatca
    36961 gattttataa agtaagtaaa gttatctcca catgaaacat gctttacatc tgatacatta
    37021 atctgcacaa attcatctac ttgatttata gataaatctt gcaataattc tccatggtag
    37081 tttgtaccac atccatacat tgttccatca ttaagtaata taataatatg agtcttagaa
    37141 atagatactt cttttatatt ttcatatgga agttcagtat aaaggtctcc tttgtacaaa
    37201 tttcctaata ctaaaccata atctatgtct tttgtggtag gtataactat cttattattt
    37261 agaagtataa agttatgtct gtttttaata gatgtcaaat ctcccattac aaagttcata
    37321 tgcttataat taaatattct attatcatta tttctactat cgtatctatt tccaacacct
    37381 aattgtccat agttatttaa tccacaaata tatatatcat tagtatcttt tattgctata
    37441 tttgcatatt ctaaaggaag tattttcttt actcttgtat tggtttttat aaatgtatct
    37501 ctttttgtta catcaccaac acctaattgc ccacaatcat taaaacctgt accatataag
    37561 tctccattat cgcttacata atgtccacat ctataattca ttccaatgtc ctttgccttt
    37621 gatgctattt ttttaatctt ctctggagtc tcacttcctg tacctgaacc attactacat
    37681 ttacctgcag tatatacatc cccttcactt gtaagtaaaa gtactgcatt atttctgttt
    37741 ggagctactt ttactacatt tgaaattgga atttcagaaa atgaactttg attactgtta
    37801 ctatttagac ctaaacaata atcagtattt aaacctgtac tatatgcagt attatagatt
    37861 gttattatat aagtatttat ttcatttggt ataacttctt ttacattttc catacacttt
    37921 ataaaactgt actggtcagt agtatttccc atacctaatt gtgaattatt attgtatcca
    37981 caacaatatg caatgtttgt atcctttaca atgaatgttg ttgtatctga gcagtacaca
    38041 tctcttacat tagttatatt gtttacagta aatgtcaata cgtctggatg gttgctttcg
    38101 cttcctaagc ccagttgccc atgagtgttt tctccacatg aatataatgt gttatcatct
    38161 ttgattgcat gtgagtgggt agtccctaaa acaacatctc ttacattttg tatatttact
    38221 ttggtaaatg tgtttctatt tactatatca cctaatccca gttgtccttt ggtatttaat
    38281 cctgtggagt atagtgctcc atcatttcta attgcaaatg ttgtgttacc atctatactt
    38341 gttgatattt tctttatatt atcaaggttt atctgagtga acttatttct atttattatg
    38401 tcacctaatc ccagttgtcc agaactatta tttcctgtgg cataggctgt tccatcattt
    38461 tttactataa acattgtatt tcttgatgtt gtaatttctt ttatatcatc cataaatata
    38521 aatgagtttg attgttcagt tatatttgtg aattttctta ttggttgatt gttatattct
    38581 cctataccta gtttgttaaa ttgatttgtt cctgttacat atatattgtt gtttttatct
    38641 actactacta cagtgttatt ttttacaatt atatctttta tgtcttttaa tcctgtatca
    38701 taactactta caccatctag atttgttata tttccaaatt ctccattatt agcaactcca
    38761 tgtccatata gtttagaact gctagaagtt ataataaaaa gacttcccaa atttgaatat
    38821 tcagaactaa tagtagtgta acttttatat ccagtagcag aagaaccaaa tgtttttgga
    38881 tatccagtaa catatgtact acctttttta aagtataata tattatttga tgttcctatt
    38941 actttttcta ttccattaaa agcgtttact tgtgtaaagt aagtattata ataagaactc
    39001 gtagtttcaa taaaacttcc atatcttgaa tagtcattta tacttggatt gctctttgat
    39061 gtatctggat atctatgctg tcctgctaaa taaacaaatc cacttttgtc aattattgca
    39121 caaccataat taaaaggaaa aacattaact attttaggta aatcacttag attgctagaa
    39181 ctagtagaca atgtaactgt tctatactta gatactaatg ttttatttgt gctactacta
    39241 ttgcctgtac ctaattgata gtaactatta tatccagata catataattt tccttcacta
    39301 tttatcatat atacagaacg ataatatgtt gctatctttt ctataccatt tatattttgc
    39361 ttatctgggt aattagaagt tctttctata ttactattag cactataacc ccacccatat
    39421 acttcttttg aatgatttag tgctataata tattcacttt ctacacaaaa ctcttttaca
    39481 ttctctattt ctatttttgt aaatatattt ctattaactt catcttttaa ccctaatatc
    39541 ccataattat ttaaaccaca tgaatataat gttccattat tcttaagtac aaaagttgag
    39601 tttccatttc cctttatatc caaaacatta tctatatcca ccttagtcat aactgacctg
    39661 ttaacagtat ctcccagtcc caactgtcca taattattta aaccacaagc atataacgta
    39721 ccatcattca taacaataaa catattatta tctgttaact ctatcttctt ataatcctga
    39781 aaattatcac ttaactttac atttaaaaat tcactattat cctttgtaac atacaaataa
    39841 tcatcattaa ccaataaacc tgaataatta tctaaatttg aagattgtac ctttgaaaac
    39901 tcatacagaa aagttgtatg aaaaaatgaa ccaagttgac ctgccagatt acagccagat
    39961 acaaatattt cttttgaacc atttattaaa aaattaaatt gagaaccaca tttaatatct
    40021 tttatatttt ctacattaac cttaacaaaa gtatttctgg atgctacatc tttattggca
    40081 ttggctagtt gaccataatt gttttgtcct gtactaaata gtgtattatc gtattttaat
    40141 atcatagtat gattatttcc acaagaagca tacttaacat tatttatact agaaagagta
    40201 aatacaattg aattattatt atttcctgta ccaagctgac caactccatt atagcctgta
    40261 gtatacatag ttccatcatt cttaataaga attgtatgac tactaccaca cgctatctgt
    40321 tttacattgt ccataccttc tattttatta aaaacacttt tatttaaagt actattaatt
    40381 cccaactgcc catttgaatt taatccacat gcatgtgctg tcccatccat ttttatgata
    40441 aatacagatt ggttataagt tattacatcc tttacactat ctatatttac tttagtgaaa
    40501 gtagctctat tgttagtatc acctaatcca agttgaccac ttgagtttaa acctgctgaa
    40561 tataatgttc catcattttt aagtacaaaa gtaaagtcat aaccacatgc aacagttttt
    40621 acatcatata ttggtagctt agtaaattca taatatactg tagactcaat tacacctaat
    40681 tgacctacat tgcttgttcc tgctccatat gcaaatccat ctttagttac tgctacactg
    40741 tgttttgaac cacaagatac atattttaca ttatcaattt ttactttact aaacatcctt
    40801 ctctctgacg aatcttttcc aagtcctagt tgaaaacctg tattatcgcc acaagcatat
    40861 aaattaccat ctgattttaa accaaaagta ctattactta taccagtaaa aaattccaca
    40921 aaatcataat cattatatct tttatcaaaa tcatcaatca atatgttctt atcattaaaa
    40981 taagcaccac gttgtaaaag tttattttgc ttcattatta gtactacctc ctttatttat
    41041 cttatttcat atgaatattt acttagagtt atatcttttt gttcttttaa ataagtatta
    41101 ctagattttg tctcaacaaa gttattatcc atatcatgta tatatctaac tctatttgca
    41161 ctaaatggta atactacatc tctaaaaatc acattaccaa tttcacctgt tatgcatttt
    41221 ctatttaaat ctaacttaag cccttctata gctactatgt tatttccatt tgttaatgta
    41281 tcataccaat aaccagcctc atctacagtt acctctgatt ctaattctag gtatattaat
    41341 atatctaaca ctttttcaga taatttgtta tagctatttt ttaatactga tatatcagtt
    41401 tgtatttgac cacttataac atcatcaaaa gatatgtttt ctattttttt aactacctca
    41461 tttatggctc ctgataaatc tttggaatct gtagttaata tatttacatc accaatgttt
    41521 acttttattt cttttatatt tttatcgaac ttatcatcta aatcttgaat atccttttga
    41581 gttacaaaaa ccaatgtcgg gtctacttct aatgtaacat ttgaagtatt ggacaattgt
    41641 aaaatcattt ttacaaccaa atctttaata ctgccatctt cagcacgtgg cttatacgtc
    41701 tctggatact tacctatagc tattatatta ttctcattat ccagaacagc agcttctctt
    41761 atcataaatc caccaactgt tcctggtaaa atagtctcta taactatcca attaggattt
    41821 ttttcatcaa ttcttagaga atttatattt ccttcccaaa ctacattctt taaagcagtt
    41881 tgttcctctg ttggctcata atattctcca ttactatctc caacttgaaa cttggttagt
    41941 ccaacaagtt ctcctagtgc agttgcattt gctatttttt ctctaccaat tttggttaat
    42001 attatataaa atttttcttc caattatacc acctccgatt taggataaac tactacattt
    42061 tctacacctg tatcatttgc aatagctata ttaatcttac aattattttc aatacattta
    42121 atgcttaaag gataaacctt tatttcttct ctacttaaca ttccagctcc acagtttaca
    42181 acagcactgc attttataat tggttcaaag tatggatgaa cttttacctc ttcactacat
    42241 accatacctc caccacaata gactatactt ttatctagta ttattggttc taaatagtgt
    42301 aataagtgag caggttttac tctttcaatc atatcgctac aatctaaaag agttttatag
    42361 tcacagttat ttgctataaa actcaatacg aatgtaaatt catcactata aacttttata
    42421 tctgtttctg attttgtata tgcctcacat atacttttta taacttcaat agtactagta
    42481 cctctgcttc tcattttagc ttttatattg ctacgtcttg tgtcaaaatc aagttctttt
    42541 ttttcaatgc agagtatatc ttcccacata tctaatcccc atgtcgctgt atcaacaaat
    42601 aattggttga aggtatcatc aatatcttct ttaagaatat ttaattctgt atcgtatgca
    42661 ccttgtatct cttctacaat gtaatttcta tcaaatgatg gtagtttatc aatcagcttc
    42721 attgattttc cacctcacta aaattaacag ttgttacact aggtatttta tcttcattaa
    42781 tagttatatt gtctgtactt ccatttataa gtaggttgct taaatcatgt acaccagcag
    42841 tatttataag tattcccatg acttttgtat agattatctc tcctctaata tctctaaagt
    42901 atgtatttat actttctagg aaagattctt tgacattatc caatgtatat ccatcttcta
    42961 gtttcattac tgcacttata tttatttcta ttggtaatgg cgtcacaact gttatagttg
    43021 gtccaatagg cttctcttca tctatatgtt gttgacatct ttcaatcgtt tctgtatcaa
    43081 cagcttgatt atttttccca aatatcaaga ctttaactgt tcctggacca tcccatcttg
    43141 gataaacctt aacattatag actccatcta cttccaaagc ccattcttca taatgagctt
    43201 tatttccact tgtagcttga tttctttgga ttttataaaa tctttccttt agctcttcat
    43261 ctgtctctat atctgtacca ccttcaaaac ttcttgtgtt agtaatcttt gttactccag
    43321 atatattatc aactagttta aattcacaat ttgtaggtaa attatatctc ttaccaactt
    43381 ccagagcttg aactggacta ttgtcacctt cctcactacc aatagttaca tcttttatta
    43441 ctacaaagag taaatctcta tatgatatta ctgtgccatt atttattaca gttccattct
    43501 ctccaataaa ttcaacttct ccatttgact ctgtacccaa ctttctatat acaccaaatt
    43561 cattgactct tttatcaaga aactggttat atgtgtcttg tataaaagcc attttatgta
    43621 tctttgaaag ttctagatat atctttgaaa gttctagatt gtttccagat atcatgttgt
    43681 ttagaaaaga accttctcct ttataaatat caagattaat attttcaaga gttctatttt
    43741 ttattacttc atatgtctgg tcactataca tttatttcca cctccccata gatagtggat
    43801 acttttacat ttgcactcaa tatgtctctg ttaaagttag cacttcttac acttacttct
    43861 aatatatatg gatttattag aagggcctct tttatgaatc tactagcttc actttctgta
    43921 agaccttttg tatatttttg tcctattagt tctgaaagct ctgtcccata ttctaaagag
    43981 tatatctcat gttcatatct atttgtcttt atacacttgt atatccaaac ttttaaggct
    44041 tcttttttct caattatttt aaaatcacct ttttctaaaa taggttcatc tttttcaaaa
    44101 tcccatgcca cttcacgaaa gattggcaat tcttctgttt taggtaagat ataatcctct
    44161 gggacaccta taaaaggaaa tattgtactc attataagct caccaactta cttacaatag
    44221 caaatttttc gcctattcta aacattatta ccatatcccc agattcaaaa gtatctataa
    44281 atggattttt tacttcatgt ttgtgttctt gatttgtttc tgtatcaaat gtttctatct
    44341 gtctatcaag catccaacta tctatcaaaa tatcttcttt ttctaatatg atgttatttg
    44401 tctctatctt taaatctggt aatttacttt taatttttcc aataaaaaaa gaaggttgat
    44461 tatgatgctt tccttcttct cttattattc ctataaattc atttattgga ttagccatta
    44521 tatcaccatc cttttataat actctccttg ctgtattaaa atcttttcta ctacttaact
    44581 tacttatttt aactacatca cctttttgtg gagcatgtaa aaattctcca ttacctatat
    44641 atagtccaac atggctgact ggattatgaa aaaatactaa atctcctgct tgaagatttt
    44701 tttgttctac tttcttgcct tttttagatt gttgatttga tgttcttggc aaactaacat
    44761 taactttttt aaaacaatag accattaaac cagaacagtc aaaactactt ggtccatttc
    44821 caccccattt atatggttta cctagatgtt tttttgcttc tgatattact attttagctt
    44881 tatcagatac attaccagaa taaccaccga taataatttt tccttttctt cttccaaatt
    44941 tactagcttc ttcaacattt ccaaataaaa tatctatgtg gtatgttcca ttcttttcta
    45001 tagttattgc aggtcctacg tcatttactt tatagactcc atcacgacca gaaactcctg
    45061 taattacctg tatttcatct ccatagttta atagaggatg tttatttaaa aactcttttg
    45121 tataataagt ttgctcatat ttaccaacca taggagcagc gcaagttttt ttagatgggt
    45181 caagtttttt ctttctacaa tctgtatctc caccttcttc ttttctagga cagtaagctg
    45241 taaattctgc tgtaaactct tttcctcctg cataaccttc tcctcctaaa ttactttctt
    45301 ccttaggttc atcctgtcct gctgactttt catccataag attttgaaaa ttaagttcaa
    45361 gttcaatttg atactctcca ttttgccagg tatgtttgtc tgtatctata taaaatagtc
    45421 ctacaagctt tgtataagaa tctttgactt ttacccctct accagttata caacttacat
    45481 ctccataacc tttaagagaa cagctttttt ctatcccatt aaactcgcta tcaatatcta
    45541 catcttgatt ttcttgttgc tgaattactt tttgcattat tacatttact tccttaaaaa
    45601 tttcattatc tattttttcg ctaatcttac ttccatactg gtctaccact attactttat
    45661 tttttacatt ttccatactc tccgaaaagg tggtatttat aatattaaat ccctcttcaa
    45721 acataacact taatgtaaca gttccttttt caataacatt aaacttatct aaatttgcct
    45781 ctatcatata ctttttcttt gtctttttac ttgcctctgt atatgcactc attattgtgt
    45841 cataaccatt tactcctata aacatctttg tatacttgac attggtcttt gctattgttc
    45901 caactgaaat cctattttca gcaaatactt gctttgctat gtcttcaact aacttatctt
    45961 taaaattgta tgacacttca ctttgcataa gtagaaatcc catatcttta gatacaaaac
    46021 taatttcatt actgcttgaa tctttagacc tattaattat cattcctcta aaaagttctt
    46081 tatcatctac gtagaaacaa actgtactag ctattggtat atctatctgt tggaaattta
    46141 catcaaatga tgattgtatt attgaaaact ctagtgtcct tgatggagat ttataatcac
    46201 ctgaccatga taccttgtct actatgtcag ttatgtcata tatacttccg ttttttatgt
    46261 gtacccaaat cttaataata aaaaatcacc tgccttttca tttaattcta tcagcagtta
    46321 tttataactt attatctata atagttattg ttttggagtt acttttggta tttttattct
    46381 tttatactct tttaagtcta atgtaaaata cacatctcga gtcccatctc gttcttcata
    46441 gctaaagccc tcaattatga cctccatatt tatatttgtt tctgtaattg taaatcttag
    46501 tataaaacct tccttcatcc atttttcaat cttatttaca caatcatatg gtgatggaaa
    46561 acctgtatag tcacagaaag tatagtcttt atttggaaaa aaacttgata ttgaaatgct
    46621 tttaagagct acaccaccaa aagttgctat ttcacctatt ttgagtatac tagaagagtt
    46681 tacagtagct tttccattaa tactaaagga agatggaaat actggaaatc taaatctatc
    46741 ttcggcttgt ctaagccaca tttccattat aatacacctc ccaattgtgc catttttata
    46801 cttgaaacta attttgatgt aactttttct atatcagctt cttctctaat cactattgta
    46861 tcagctaact tagctatgtt tatatttcca ccattttttc tgcttctata ttgatttgct
    46921 tcttgtttag ttaaaaccat ttcaccttca tggagtctgg tttgatagtc attataagga
    46981 acatagttca atccaaatgc attattacct ttcttacttg aataagcttt accagaatca
    47041 ccagcctttg ttccagcata tggattatct ttgtaatttt ttttactctt ttccactaga
    47101 tttaaaactg ttcctgtgat gcttccattt tttatcttat taatcatagt ttgccaccat
    47161 ttgcatatat ctttaactat tttacatact ttatctaata tgttaaaaaa agctcccaat
    47221 attggctcta taattttcca tccagtttcc aacagaggtc ctaaggtctc ccatacagtt
    47281 ttccaaataa cacccagtgt ctctataaaa ttgtttattt gaggtgcata ttcacctaaa
    47341 aaagtaaaaa ttcttgtgat aataggacta acagcttcaa ctacaggccc gattaattgg
    47401 aatgctgtag ttactattgt accaaatata cttattaatc cttgtgcaat tggtgattta
    47461 ttgtttatac tatctagtaa attatttact aagtttacta ctggaagtaa tgaatctatt
    47521 aatgctgtaa aatcgatatt ttgtaatagt gtacttcctg cgttaacaat tgcttttggt
    47581 gcattcccta tcattgttgc tgcatgattt tcaaaacgtt cttgcttatt ttcaaccatc
    47641 attttacgct tttcagcctc attagaaatt cgatattgag tagaatcaga aaactctttt
    47701 ccatttttta cacttctaga ttgcatctgg tcatatttgt tgccaataat tatcttacca
    47761 ttcattacat tgcctatttt accagccatt ttttcagata agccagctaa attgcctaat
    47821 ccactttcta taaaagtttt tattttcttt agtccttgac ctaaaatatc atcaaaaggt
    47881 ttaacaatac tcttcaaacc attgttaatg ctcgtttgag ctcctgatat tatacctggt
    47941 attgtattac tcatttcttt agctaatccc atctgcttta cacttatacc ttccaatgct
    48001 tcatcaaaag ttttataatt ttctcctacc agagtattaa gagattccat atttcctttt
    48061 gctgcactta agaaagctgc tgatacatct tgttcactac ttgtattcat atttaaagct
    48121 ctaacatcta ccatagcctg agttatatct ttttcttttt taccaccagt aatattacta
    48181 atcattttag ctttagttcc cattgcaaca acatcttcag ggtcaaaagg tgtcttatct
    48241 gctatatcta acaaatcttc ataataatta tcaacatctc tttgattaac ttttccagta
    48301 tttcttttca ttacactttc tagaacaact ttctgatttt gttcctgacc aagtaagtca
    48361 acaccctttt tcacagcgac acctatagta gcaccatttg tcaaatcaga tatcttccct
    48421 tttattgaac caagtattcc acttgccata tcctttacag ctattgcacc tctccatacc
    48481 ttacctgcaa acaatctcaa ttttggaaat actttactta taatgctact tgccatatct
    48541 tttatagcta ttacaccact ccaaaaagta tttttaaaca acattaactt aggcaaaatt
    48601 ctacccatag cactgcttac catatcttta agattaatac ttccttgata aggacgtttc
    48661 tctactcgtt ttaaatttcc caagatacta cttatcactc tcttagtcat atcttttgct
    48721 tttattacaa tcttccaaac cttgccacca atctttttta aatttccaag taatttattt
    48781 ttagtttttt ctatttcatc acttttagct ttaaatatta atataatcat aatatttgaa
    48841 tttaactcat ttttcttttg aatcaactta ttaaaataat caataatcat agctatagtt
    48901 attgctagtc tcataatact tccatttaaa cttccaataa ctcctgaaac agcatttatg
    48961 ctagaactta attttgtcat agttgaactt acactgctag cggtagtctg aacttttctt
    49021 aacgaagaat ttaaactgtt tactctacta cttgcacttc caatagaatt ttttatgcta
    49081 ctagccatca cattagtaga aagtgaaaca gccacagttg ctctcctaaa attatcagtt
    49141 actgatataa tttgattcat ttttggtgtg taattatctg taagatacat atttatacct
    49201 tcttctctta catttcccat tacataccac ctcctgtcaa aggacacact ccatatccat
    49261 gtttcatttt ttcaacttct tcctcaattt ctaaggcgaa aaaagcttca ataagcttta
    49321 attcgccttt atccattgca taaaaaaggg acggccttat accttttttc ttccaataat
    49381 agtacattat tgtagtcttg gtatccgtcc ctattagttt tttacctctt ctatcactgc
    49441 atttttacca taacccataa catcttgaag tattctatat aagttggtaa tttcacctgg
    49501 tagtaataat tttcttgcca attcttttgg tgttggagcc ttaaatttat ccattagctc
    49561 cttattttta aataaaagct ttccatctaa atcacaaaca ccttctataa ttgtaagcat
    49621 ctgcatctcc ggtaagtcta tatccgtttt catattttca tcaattttaa gacaagtatt
    49681 ttgtatctct tcatctttac ttattgttaa agctctacac attactttaa attcctgccc
    49741 aaatatagtt gataatctct taagttcaac tatagtgctc ggtctttcta agttttctgt
    49801 atctgaattt aaaagtaaat ctactatatt tatatttttt gataatccat tttcactcat
    49861 tattatttgc tcctttatca atcaaattca atcaactaac ttttttactt attaactatc
    49921 tgaatttatt aagtatatac ttactaaata tcattataaa accaaatata aaactaaatt
    49981 atatcaagaa aatcatactc agtaaatgtg aaaggtgctt ctatctctcc ttttactcca
    50041 acctcccaat cagctaaagt taaatcatca aacgctatat tttttactgc tattctttct
    50101 gctccataag aatctgggtc atttaattta gatatagcaa caaatctagg ttcagaacct
    50161 ctctttatct tttctccaat taacttatgc attcttgaac taacatggta tagagttatt
    50221 gaaccttttc ctttatatcc catatacttt gtatcagtac ccatttgacc tgctattata
    50281 atatcctctt ttgtaaattc catctttgct tgaaacttct ttacttctgc tactttgttt
    50341 ccatcaagcc aaagttctcc ccaagtacca ctcattacat ttctagcttc catatttgcc
    50401 atattaataa tcctcctata tttctattga taaatctata tcttccatag catcaagtac
    50461 ttttattttt gcttttaaaa atactttaga acctgtgtta gcttctttta tttcttgtaa
    50521 tgtcatataa gataaatcta ctccttttga ttttaaatac gatttttgtg cttcaaaatc
    50581 tatttcaaca gtagaatcag attctataag tgcagatttt tctaattctt ctaaataact
    50641 ttttatagct actatcaata aacatttgtt gtcataactg ttagtaacct ttcctatata
    50701 gtcatctatt atcacctttc ttatatcact atgtataata tctaaagtgt caactatttt
    50761 tattttctgg aacatttctc ctttttctgc tgttaattca gttaaagaat ttactcctct
    50821 agcaattctt atagctcctg cttctttaat aagtataagc tctcctttat taacccttga
    50881 ttctgcatca actttagtca tcttaggtat atcgactaca tcactaagct tagtataggt
    50941 tactgattga cttaaaggtg tacctgctat aagcccagct accctacttg taaactcatc
    51001 aacactgtat ttcttttctc caactaacac atcttctgta gtaaaattaa ttatcccttc
    51061 atgatttcct acaacttttc ctaatatagc tttaacctta accttatcta tatctctaag
    51121 tttaattatc caatttttta tagcagtctt atcagcttct actgcttttg gcatacatag
    51181 ataattaaat tccttagtct ctaggaagtc taatgcagtt tgaatatctg cttctccttc
    51241 tattacataa actaataact tatttggagt gttaacattt cccatcaaag ctaaatttat
    51301 atattcttta ttttcagcag ataaatcaac tggtatatcc tctttttcat gtatctcgtt
    51361 aagacctaat gccttagcat ctttaagcac cattgcaatt attcctctag ctgaacgttc
    51421 tttaacagtt gtagctagct ccttaaatga tatgttgata cttggtaatc ctatagccat
    51481 actatcactc tcctaaattt aaattgattt cttccatatt ttcatatact acatcttctt
    51541 catatacact atccagatag tttagtgtaa ccgaaaaatt caatgcataa attgactctt
    51601 cttttttaat actttgttct agctttgtta tatttaattt tctgtctgtt acctttatat
    51661 ttctgttaaa tagcttattt aattcatctg aaatttcata cattctaata ctctttgact
    51721 gtggttttgg taagtatttt atagagataa caatatcttt gttattcgta tttaacatta
    51781 taggtgtaca aataactgat aatatactta caaaaaaaca agactcttca gagccttgca
    51841 cactttcatc atcaataaaa atactttcag taaagttttt tttgagaatc tcaataattg
    51901 tttctaatat ttccttgtat ttaagcaaat aatcaccaca ctatcactaa atattcttgc
    51961 ttaatctgat aatcttacta taaatgatat aagtcatttt taaatataca tctcatttat
    52021 tcctgtcaag tatcttctat atttctaggt aatattattc ttttcaatct atcacctcct
    52081 tcaatatgga tttctttcac aataacatta tctcacatat tttattacct attgttgcaa
    52141 tgttgtatat aaagtgttgt aaaattgtcc tattttttat aatatctcac tcaatttaac
    52201 tatcatcttt ttctttaagt tgtagcagga tgttctatct aagtgtagtt tcatagaaat
    52261 atacgtcata ttgttttttg tcttactatt ataaaaaaga ttaaaaaatt ccatttctat
    52321 atcatttaga catgttagag cattttctat cttctctttt tctatttcta tatcttcttt
    52381 ttctattttt aattttctta atcgttcctc ccttttcaac acctcatttt ctacagagga
    52441 acttatatta tatgtgttac tagtcttttc tgtatatacc attgctccac atccagagta
    52501 ttcattttca tatcttttta tatctaaatt aatgttcttt atctttatat ccaaatactt
    52561 gtaattatgt aatctttcat ctgtttcttt aaataatata tcttttttgt tttccatagt
    52621 atttctcctt tttatatatt tattgttagc ttcaaattta caacaatctt tttagtacta
    52681 atttttttat taatcttaat aattttaaga acattttgtt ctataactgt ataaaaaaaa
    52741 cttcttctat attttgttct aaaatgctag aaatcttctt ggccataaga agcccaggat
    52801 tttttatacc tctttctatt tgagatatat aatcatttgt aattccagcc tttctagcaa
    52861 gttgaatttg tgtcattcct ttgcattttc tataatattt caaattattt ttaaacattg
    52921 ttttatacct ccattactat taagaatatt ttgttctcct atatttagat tatatagaat
    52981 tatttgttct ttatcaatag attttagaaa aaaatattct tttatacttt actagtttta
    53041 ttttttagaa caatttgtta taatctatac ataaggtggt gttataatgt ttgccaaaag
    53101 attaagagaa cttagaaagg aatttggatt gactcaaaga gaacttggag aaaaagtagg
    53161 tgtttcccaa agagtcttag gatactatga aacagaaaac agatttcctg atgaacacat
    53221 tttaaataaa ttggctgatg tatttgacgt atcagttgat taccttcttg gaagaaccct
    53281 agttaaggaa aatattgata cagtagctgc acatagaaaa aatccacatg aagagttacc
    53341 tgaagaagca caagaacaac ttaatgatta tatagaattt ttactaaata aatataaaaa
    53401 aaaataaacc atatgatgag cagtctattt ttctgctctt ttaatataac tcaaaggcaa
    53461 acatacattc tattttaggg ggatttttat gaataatttg gataagcttt ttgaattagc
    53521 ttctcaagaa gagataataa ttcattatac cacttatatt gcaggtgatt tagaaggact
    53581 atatataaat aagcacggta tgaaaatcat atcattactc agtaatttaa aacaaaatac
    53641 aaaaaaattg acatccatct tagctgaaga acttggacat cattttacta gtcttggata
    53701 ctatgtatcc tcttataatg attattatac aaaaatcatt atagataagt gtgaaaataa
    53761 agccttaaaa tgggcttgtg agttcttaat tactgaagag gatataatag gcataattaa
    53821 ttctggcgtc acttgcgttt atgaaatggc agatatactt aatgtggaaa ttaatttttt
    53881 tcaaaaaaga ttagaatttt tatcattaaa aaaacagtct ttacaacttg gaaataataa
    53941 atatttaata ttaactaatt tgccgtattt ctacatattt gatccaattt cataataaaa
    54001 atagtagtaa ttttaactgg cttaccagta aaatctatat atttatttta acaaattttg
    54061 gtttctataa attcaatatt aatatataat aatgatatca tattatttaa aattctaaaa
    54121 acaaatatat gcttttgtta agaaaggttg tttgatgaat gtataaagaa aagttgtttg
    54181 ataattattt taagttctta gcattatttt tttggccaat aatgtggtat aagtggatag
    54241 taatttcaaa tggtactctt gaaaatatgt tatttaccac ctacgcaatt attgcaattg
    54301 ttttcatcat tttatattca gtatctatga taaaatataa agacattaca caaatagatt
    54361 tcttttacag gataagtact ctacttgctt ttatatttac actttttagc ttcttaatat
    54421 acccaaagag tttatttttc ttgtatttaa agattatttt tactggaata tacctttatt
    54481 attcaatagt aaaaacactt aaatttaaag atgacgaggg tgtagtgggt attatgagct
    54541 cacttttatt aattgtaata actttattct actaaattta attctatttg acttaatatg
    54601 gctttaaata ttagacatct acattgtttt ctgatattat ttaagatggt agttttatat
    54661 taataatgaa atacactatg aaggagttaa ctattatgga aaaaaaagtt ttagcaacag
    54721 ttggagaaaa agagataact aatattgaca ttgaaaatgc attaaaatca ttagaccctt
    54781 atcaagctat gcaatttaaa actgaagaag gaaaaaaaca cttactaaat gatttagtaa
    54841 atcaagaatt attcttctta gatgctaagg aagaaaaatt agatgaagaa gaaatattta
    54901 agttagaaat gaaaaagata gaagaaaatg tattaaagca atttgctata aataaagttt
    54961 tatctagtgt taatgtaaca gaagatgaaa aagtaaaatt ctttgaagct aataagagtt
    55021 ctttctctaa accagaaagt gcaactgcta aacatatatt agtagatagt gatgaaaaag
    55081 ctaaagaaat acttgctcaa ataaaatcag aagaaatatc ttttgaagat gcagctctta
    55141 aacattcttc ttgcccatct aaagatatgg gtggtgattt aggaacattc ggtagaggac
    55201 aaatggttcc tgaatttgaa gaagctgtat tctctatggc taaaggtgaa gtaagtgagc
    55261 cagttaaaac tcaatttgga tatcatataa taaaattaga agaccttcaa gaaagtacag
    55321 agtctacatt tgatgaagtt aaggctgagg ttgaaaaaag tttattatat caaaaacaaa
    55381 atgaagttta tggaaataag ataaacgctc ttaatgctaa gtatggaaac cttgtaaaat
    55441 acaacgatta atcataaagt aatgtataaa aaagctgtct tttcacaata tttattataa
    55501 aagacagctt tttatattaa agtttaaata tccagcttaa tattatcatt cttttattgc
    55561 aaagaactca gcttaaaagt ttaaataaga tttttaatta tcattagcta aatttttata
    55621 tccacgtatt atctcataac aataacctat tacatctctt ctttttatta tcccaataaa
    55681 tgtgtcttgg tcatctataa caggaatgaa gttttgattt aaagatttta taactaaatc
    55741 ttcaatatct gcgttgatgg aaacaggaga attatccatt tttctattaa tatctgtcac
    55801 tggaacatct tccaatccct ttaagtccag atttaaatcg ttttttaatg tccataaaaa
    55861 atcaccttct gttatagttc caacatattt accatcctta cttattattg gaattgcaga
    55921 gtatttgtga tattccattt tttctagagc ttgccttata gtgtagtctt catatatata
    55981 tgctacttca ctttttggtg ttagaaagaa taatatgttc attacactac ccaccgttac
    56041 tgaaaactta taaatattat tcaatattta taatgttact tttttgcagt aactttctcc
    56101 tttcttattt tctaagtatt cttaatacta tacgctgtaa caagcgtttt tcttttggtc
    56161 attttaatct tattatgctt tattaatatt tttatatggt ctatcagtat cacttattct
    56221 ctttttagaa aattcactaa aaattaattg acttaaactt agccataata attttactct
    56281 acactattaa ttttaacata tttatctcat tattaatgat tttattttaa taattttaat
    56341 ttattttgat attaatttta tttacaaaaa ctgaaaaaac cgctaaatga ttagcggctt
    56401 atctctcata ttactagaac actaatatat atgaattttt aattataatc taactacgtt
    56461 agcagcttga ggacctttag ctccatctac tacttcgaac tcaacgcttt gtccttcttc
    56521 taatgttttg tatccatctc cagttatagc tgagaaatgt acgaaaacat ctccttcacc
    56581 ttctacagat atgaatccaa atcctttttc gttgttaaac catttaacta caccagtttt
    56641 cattaataaa tcctcctaaa aaaacacaaa tatttagcta ctcttttctg taaccttatt
    56701 actactctat catatatagc tatgtttgtc aattattatt atttttatac attaataatc
    56761 aattttttta ctttataatt ttaaatcatt attatctttt acactttatt tttctttata
    56821 ttttttcaat aatttatttt tattatatgg aatcttatgg acttatcact ccaacctaaa
    56881 tcccatggca ccaacattct atccgtatta tggcaagtta ccaaaggata tcctcttgag
    56941 tctaatcctg tcactgtcga aacatgtgtt attctgcctt tcttctcata accaacaaaa
    57001 tctcctggac gtaaattata agcttctttg tatacttctt cataagaacc tttagcaatt
    57061 aatgaacctc ttccactata cagtgcataa tttttaaaag cttgtgcatt tacccatgct
    57121 tttgtacctg ctctttcact ataattccaa attgagttct ttttgaacct tccactttca
    57181 aacattatct gtgatgcaaa gtttgcacaa tctccacctt ctggattata atccctatag
    57241 tttggattaa atttcatacc atgttcttca tcagctgcgg ctccacagta tttatgtgca
    57301 taatctattg cctttttttg ctcatctgta agctgtaact ctacaccatc ttgttgacca
    57361 atatagtttc ttatatcatc agattttata ttttctaaat ttaaagagtc tgcaaaaggg
    57421 tctgtatacc actctttagt tatgacatat tgattatcta taatttttac atttagataa
    57481 tgatatgtac ctattctaaa ggcattttct ttgtcctttt gattttcata tgaatactta
    57541 tattcagtcg atactgaaca gattatacca tagaggtctt tttctttttc ctttattttt
    57601 ttaatcttaa cccttgtctt tatatcttta aattttacgc cttgcttact agaccagttt
    57661 tctaaatact tcatcttttt tacttcattt tcataagccc aaagaccaaa ttttttatct
    57721 gtctcataaa gaccttttaa aatattttca tttttctcta atattgcctt atttctgtag
    57781 tcaaataagt tttcaagcaa tagtttatat tggtctttta catcatcacc ttcaatattt
    57841 gcagattcca tgactttttc ttccatattt ttcatactta aatcattgat taaaaataca
    57901 cctgctgtag tagctaaaga taaaaataca aatgccatta tacctttgat gtacttattc
    57961 ttatttttca gtattttcaa agctacacct cccaaatagt acaccttaca aatcaaatta
    58021 caaagaatat tctgtcacat acaataattt tcatacttaa taattctata ttttattatg
    58081 tccaatatta aaaattaatt gtatcaatac actgtttttt ttacaatttt ttattttata
    58141 atctactttt ttcttttttt tatagtaata tatatgtata taaatatttt ggtatcatta
    58201 taattaatac atactaatgg agggtttttt atgcaaaaaa aagtcgcagc aattaatgac
    58261 ttatctggaa taggaaaatg ctcattatca gttgctatac ctatactttc agcattaaag
    58321 gttcaatgtt gtccatttcc aacagccata ctttcaagtc aaactggtta tcctgaattt
    58381 acttttttag actttactga tgaaatggta aaatattcaa atgtttggaa aaatttaaaa
    58441 gtccactttg atagtatata cagtggtttt ttgggttcaa agcatcaaat tgagatagtg
    58501 gctaatttta taaatgatta tcccaatgct tttattgtag ttgaccctgt gatgggtgat
    58561 aatggagtta tgtatccaat attcacagaa gagatgagac aagaaattaa agaattagtt
    58621 aaacattcag atttgactac tcctaattta acagaagctt gtttcttaac tggaaatgat
    58681 tatactaaaa gtgattataa tagagatgaa cttatatata ttgcaaaatc tgtatctgat
    58741 ttaggaccta gcaaagtcgt tattactggt atattagaag atgaaaacat actaaactta
    58801 gcttatgata gagataatga ccatgtattc tttacatcag ttaaatacaa taattgttct
    58861 tatagcggaa ctggagatat attcacatct atactttgtg gtatgttagt aaataaacat
    58921 gatttaggag tagctgttaa tactgcaaca gattttatat ataaaactat aaattacaca
    58981 tctcaatttg atactgatag aaatgatgga gttatgtttg aaaacttttt atcagattta
    59041 actaatatat aaaatcaaaa aaattatcca ttttataaat acctatgaat cataaaattt
    59101 aggtatttac aaaatggata ttatttacta aactattggt atttcaattg ttaccatagc
    59161 accaccagtt tttatagagt tttcaatatg taaaatccca ttatgttttt gtacaatatt
    59221 atttacaata taaagaccca ttccataatg agatttagag tttctactta aatctcctgt
    59281 ataaaattgt cctgtagcct ttgacaaatc tgctttagaa aaaccacttc cacaatctgt
    59341 aatcacaaat tttaagtatt tattacttac tgatacactt atgtatagtt tactctggct
    59401 tggtgaataa tctatagcat ttgaaattac attcataata gctctaaata acaattcttt
    59461 atctatagtt atactttcag gcaaattacc ttgtttagaa aattcaacat tcaagttttg
    59521 tgtacgagct aatgcttcta tttgaatcaa gatatcttct ataaattcac ttacattaat
    59581 tacttcttta tttaatatat aaccagtctc tgtttttgat atctctatta gtgtattaat
    59641 atatttttct atttgggtgg caccttttgc tatatattcc atgtattctg ataactctgg
    59701 attttcattt atttcaatta gtaagtcagt atttccatgt ataatagtca atggtgtttt
    59761 tatatcatgt gctaatgcag atatctgttc cttacgattc tcttctaaca tccactgttt
    59821 ttctaaagaa tcttttaaag ctaacttcat tttatccata gaaaaaagaa cattattgat
    59881 ttcacggatt ttactagatt ctataacaaa atctaaatcc tgctgttcta ttttttctgt
    59941 agtatttttt aaaagttcca tttcagcatt taattttttg ccaaataatt ttgatagtat
    60001 aataatttca ataagaaata ttatactaaa aataatcatt cctaatagtt ctggctttgg
    60061 taaatatgtc cttaaagttg gagaaacaaa ttctgctact atactataac gtattataca
    60121 aacttcattt tttctggaca atttgatata gttttttgat gacgtaatag tccttctttc
    60181 aaatcctcgc atcaaatccc atacttcttt tgactcattc ttattgaaag ttcctgaaat
    60241 tactttgcca tttaaagtat acactccata ctcacataaa tctggaatta aatctttagt
    60301 tacttgttta cttgaaataa tcttatcttt attttcatag atttgttttt ccacataatt
    60361 agcaggtaat attatattta atgataataa tataggaaat gataatatca atatagatac
    60421 taagacaacg gttatagcaa agaataaaga tgaatatctt acaaaaacag ttctaagtgt
    60481 tacaatcttt ttattattaa actttttacc tacaagtatc ctcaccacat cctccaaact
    60541 ttaattagtt tatagttaat tataaactag cttttgattt gattattttt tatttttatc
    60601 actaaactat attctaacat aataatataa gtaaatagta acttttttat ttttattctt
    60661 cagacttttt accctcccat ttagaaaacc aaatacataa aattataaat gctaaaatgg
    60721 ttacaaatcc acatactaat cctattgatt gatatccttt aattgattcg actttaatat
    60781 attcaattgt cttagaactt gaaaaagatg accatatact tataaatcta acaccccata
    60841 cacaaggaat ataaggccaa attctagcac ctaatccagt tagcaacact gctgagagta
    60901 aagtttctac tatacccact ccaattgagg ctccttttcc aaatcttaaa cttaagaata
    60961 aatgtaatat atatacaaat aaattactcc caactaaaat cataattgaa atcatataaa
    61021 aatctaatgt aaaataaacc tcattagaaa tactagatac accaaattta aaacctaata
    61081 cagatactag tgttgctcca aaaccaaggc agattaatat tatatactta cttataagtg
    61141 taagatattt tggattagat gatgttaaca tatgtttata acttcctgaa taatactctt
    61201 gttcaataca taatgaacac ataatacttg ataataaagg aaaagctatt gctataactt
    61261 gtaaatatgc agctatcttt gatatatcat cagcacttga atacttataa tatcctaagc
    61321 acaatcccat gcctattaaa gcaatgcaaa agtgcattag tattataaaa gttcgcttta
    61381 attttattaa atcagaacaa aaaattctta ctagttgtgt catattactt cacctctcta
    61441 ttattgaacc aagcatttgt agctaaagaa agtaatataa ataaaacaat agatattaac
    61501 actcctggca aaattacatt actatttaaa aactcacttc cttctggtac aggaagtcca
    61561 tttggtagaa tatgcaatac aggagccatt aatcgtggag taattgaata tggaaatgca
    61621 taccacattt ctgtagtcga aaaaacggca actccaatta tagtaaaaaa catgtttatt
    61681 ataattgtaa taaacatacc aaattttgat gccaaaaaca tacaaagagg aatctgccac
    61741 ataaataata aaactaataa tatggttcca ataatatttt gacttactga aataacttcc
    61801 ttatataaca tcccaacaag aaatatacct atcataaaaa taattgaggt tataaaacaa
    61861 catataatgc aataaagtat ttttccagtc caaacatctt ttttttcaat tggcaatgat
    61921 aaaattccac gatacttctt tttttcatct ttttgtacta ttagagaaga aatcaatgtt
    61981 aatacacctg gaagaaacat agtgtaccac caattataaa caccattttg tcctccacca
    62041 agtaaaaatg taatgattat agaaaatatt ggggctatcc atatcaatct aattccaaaa
    62101 gttcttttca ttttttgaaa ttctgctcta actaattttt ccatattaat ttcctctctt
    62161 tctattttca gctacaactt tcataaaaag ttcttctaaa ttttgctctt ttgatacttc
    62221 tccttgatat cctagtactc cattagaaat tattccaatt tcatctacaa cttgttcaac
    62281 ctcagacaag atatggcttg ataaaataac tgtaatccct tgctttggga aagaacgaat
    62341 caattctctt agttcttcaa tacctatagg gtcaagacca tttgtgggtt catctaagat
    62401 taaaagcttt gggtgattta ataatgcaat agcaatacca agacgttgct tcattcctag
    62461 agaaaattga cctgaacgct ttttaaaagt atctcttagg tcgacaatct ttaaaacttc
    62521 ttcaatgcga gaatcaggaa gaccaagtaa agtagtatga acttttaaat tttctcttgc
    62581 tgttaaattc tcatatatag caggagactc aataagagaa ccaatatttg ataaatcctt
    62641 tctagtccat ctatgcccct caaacattat ttttcctgaa gttggattta aaattccagt
    62701 tatcattttt aataaagtgg atttaccagc tccgtttggt cctagtaatc cataaataga
    62761 attatgttta attgctattg aaatattatc aactacaacc tcatccttaa actttttaga
    62821 aactcctttt acctccaaaa tataattact cataattttc atcctttctt ttgacaaact
    62881 tatttacaag aatcattcta aatcataaat ataaggattt tataagaatt aaaaaatcac
    62941 aaaaaaagat gtgttaaaaa acacatcttt ttttatctta actctattaa tttcccattg
    63001 tagtatattt ctacttcttc aatccaaata ctattatctt cttcttggat gacattttta
    63061 ataatattat ttatagtgta tattatattt tgctcattca aataatcatc tttccaagaa
    63121 actctacttt tttcatctgg ttctatcaag tttattttaa caagattatc tttttcctta
    63181 acttccactt ccatgtctaa accattaaaa tactcctttg ataatgtgtc taagattaat
    63241 cgtagtttat ctttaagtgt actttcttca tcaatctgta agtactttac tatcttacca
    63301 tcctttgaaa ttatctctat gggtatttta gtagtattct tagaattaat cattttacta
    63361 gttgtttctt ctctcacatc atcatccttc tttacaactg ctgactcttt agaatcaact
    63421 agctcaactg cgctgatgct ataatccata catgctgtac tcaataaagt agtagcaatt
    63481 attaaaaaac ttactgctat tttattcata agtatccctc tcctaattct ctttcgatac
    63541 ttattatacc atagtataga ttatattttt atacttttaa atcaatttat aaattattat
    63601 agtaaattat ttacaattct aatctatttg aatttatttt tatagtatat tctttctcta
    63661 aattcgacag atttttattc aaaagccctt ttatttccct cgtatttcta tacttgttgc
    63721 tatgttcttc actatgttca taatcatatg aatcattgtc atattcttca tcattattaa
    63781 attcttcgat tacttctttt gactttatat cacaattaaa tttatactta tttactggta
    63841 tatcaagtct taccttagaa tttggaactt ctatatccag atacttagca attggcatat
    63901 tagaatataa gttaaattca ttatcataat ttgagtgtct acctattttc tcctttatgt
    63961 ttacattttc aggtatatat tcttctatat tattgataaa tacaccttca tcctttgaag
    64021 atatatccaa tgactctgat tctatattta catttttaac acctaaaatt gactttgttg
    64081 atagatgaag attgctatta gatattaagt ttaagttttc taatctattt actttatttt
    64141 ctgttatagc tctgctaaaa cctccagaag aagttttata tgttatatta tttgaatcta
    64201 catcatcaga tataaataag tacgaactta tacttgatgc atttatatct acattatttg
    64261 gtacatatat tctaatttct ctataatcac gtgaaaacat actatttata gatgtattta
    64321 ataagtggtc gaaacttcta atctttttaa ttttattttc agattttctt tcgcctttta
    64381 caactaaagt cttatcttgt agggttacac tgtatttgta aaattcatta ttccctcttg
    64441 ttgtcacacg cacatcttca tttgaacttt ttcttatcat aacatttata ttgtcaacag
    64501 atacatctaa cttgtcaata tttacttttt cttgataaag tttgttttct ttgtttaatt
    64561 cagcttcctt ttctaaacca aagtttatta agcttggcat aactaaaatc cctgaccatg
    64621 ttgtccctat tatacctatt accaataata ccgcagcaaa tatggcaagt ttcttattca
    64681 tatttatctt ctcctttctt attttctata tctttaaggt ccttatatat cgcctcaaaa
    64741 tttatactat catcattata ttcatcagtt tcttttatgc tttcttcttc tctattgtag
    64801 taatcattat tatatgaatc ttcattaatg tctttattca aatcttcatc atttaaagta
    64861 gctttttttc ttttttccat cttttcattt gcctttatat aaatattttt tctctttatc
    64921 caatgtatat aattatttag taattgttta cctagtttta tggcaaatag taaaagttgc
    64981 catgcaagta tctcaatccc tacaaatgct atggttgcga aaatacaaaa catcataaca
    65041 tctggaacca ttgctataaa tttaatcaca aatggaatta atataacaaa agcaattaat
    65101 gaacatacta atgcaatagt aacagataca atagcacata caaacgcaaa tgctggaaca
    65161 attagaaata aagataacac tactaataat ccctttataa cttgtctaga taatccccct
    65221 acaccttctt ctatacttgg tgtaagttta tcatttatat tttcttttga tttattgtac
    65281 ttttccttag cttcatcttt caagatagag taatcctttt ttatatttga tttaaaccta
    65341 ctaaatttac catttaatat atctgtactc attatttttc catctatatt ttcttttgat
    65401 ttactatact tttctttagc ttcatctttt aagatagaat aacccttttt catatctgat
    65461 ttaaatttac taaacttatc atttaaaaca tctgtattta ttattttttc ctcttgaata
    65521 tttttttctt tggtctgtag gataagttct ttagctatag attttggtga accaagtgat
    65581 gatattatct ccatatcact ctttccttct ataagaccat ctacaaaata ttcttcataa
    65641 tctctcaata tatcattaac ttcgctctca gaaaaatctt tttttagata atcctttaaa
    65701 atttcaagaa actcagtttt attcaagctc attacctccc ttatcttcac ttattaaaat
    65761 ttcaacagcc tttacaaatt ctctccactc ttccatcaga ttggataaat tttcttttcc
    65821 tagtgaagtt attctatagt attttctagc aggaccttca ttagattcta gtatatatgt
    65881 ttcgaaatac aaatcttttg taagtcttct tagaatagga tatattgttc cttcatttac
    65941 atctattact ttagaaatgt tatgtactat ctcatatcca tacatatctt tcttagatat
    66001 gagagcaagt acacaaattt ctaagacacc ctttctaaat tgtgtgttca tatactccat
    66061 cctttcttta aatacacagt attgtgtttt acaaggtact atgttaaaac ttcttatatc
    66121 cccataatag cacagtacta tgttctgcac aatagttatt tttaaatatt attgttgatt
    66181 aaatccttct ataaatgtat aatactctaa tcagatatat tttatgaaag tggtgataag
    66241 ttggctaaaa tgaaagatga taaaacaata ttaatcttaa ctgctcaatt tggagctgga
    66301 catataagtg ctgcaaaagc agtcaaggaa tctattattg aaaaatacag taactataat
    66361 gttgttatac aaaactttat aaatgcaagt attcccatga tgaataagcc tatggtaaaa
    66421 ctttatgaaa acaatacaaa atatactcct ggattatata attactatta ttactttaag
    66481 aaatcgtttg attcaagaca tgatttttct cataaattat atacacctaa actttctgag
    66541 tatattgctg atataaatcc agatttgatt atctctacat ttccactagc tgctgcttgt
    66601 gtaaataact ttaagataaa aaatcctgat ataaatatac ctacacttac agttataaca
    66661 gatgttgtag atagtatgga atgggttttt gaaaatacag acttgtattt tgttccttct
    66721 cctgaaataa aaaatagatt ttttcagaaa ggaataaatc cagattccat aaaggttact
    66781 ggagttcctg tagataagag atttcaaatt gaaagtaaag aaatatgttg tgataaatat
    66841 agactattgc ttctaggtgg aggaagaggt ctatttgata tagatgagga ctttatgcat
    66901 tggatagatg aatttattga agaacatagt gattctatag aaattacaat agttactggt
    66961 aaaaacaaaa aattatacga caatctaact cataaaaaac ctctaaaaaa tattaaagta
    67021 cttggatttg taaacgacat gtataatcta ataagagagt gtgacctaat gctaactaag
    67081 cctggaggag caactatatt tgaagctatt caatcacaaa ctccagtact tgtaaaaatg
    67141 ccaaaagttg gacaagaaat tgaaaatgct aaatttataa tagataaggg gcttggcatg
    67201 atttatagtg atgacctaga cctaaaaaac atattttata ggttagtatc aaatgaattt
    67261 gattctataa taaactttat gaaaaaaaat ttagaggaat ttaaaacagt cattcatcca
    67321 gagaaaattg ctgattatat atcagaatta atagataaac attacagtta aattgtgcta
    67381 ttacaaaatt ttaaacaaaa aattaaaggc aatcaagtat gcttttacac ttgagaattt
    67441 actcatagtg cttaataata catgattgcc tttatcatat caaaatcaaa ttgttatctt
    67501 agtatatatt tttcttgtac tgcatatata gttgttgtat ttcttccata cttctcttta
    67561 actctatttg taaatctgat gcagcctgat aatctttatt ttctacagct tctctcactc
    67621 tagtaaatag cgactctcta gttaaagtat ccttcataat attgaacttt aaatctgata
    67681 ttgagttcca aactacttca tcaagtgcat ccatattttc ttttgtgtgt atcttgacaa
    67741 tacttcttat tttttgaatc ccttcttcta ttattctagt ttttaatttc ttttgccact
    67801 tatctatagc tccaatctta aaggattcta ttatactatc agtaaataca tcaccttgtt
    67861 ttaaagattt tagttttgaa gcatatattt ctaagttttt catattttca taaactgtag
    67921 ctggtgggat tccaaatctt gcatttcttt cttccaaact gtaatgttca aatacatcat
    67981 tttcatctct atatgctcta tctttttcta aatagaaact ttcttcacct acatttttag
    68041 ataattcttt ttcaagttct tttgtactaa gaccactctt agctgctgct tttataccat
    68101 ccaacattgt ttgataacac cctgctatta ctaaatatgt gttagataga gggcttggtg
    68161 atctcaactc aaatcttaca gtctttggat ttttcatatc tcttattaat ccaacaagca
    68221 ctgacctatt tcttgatgga atctcataac tatgacctaa agatgtaact atacatacag
    68281 gagcttcaaa tccaggaact aatctattaa atccatcatt agaagctgtt acaattgggt
    68341 ttaaaacttc atagttgtaa agaagtccca taagagcccc atatcccagt tcacttagat
    68401 aatcttcttt taaatctttt ggagcaaata gattttttat acttccatcc tttaacttcg
    68461 cacttactcc tacatgtgtg tgtccaccac ttcctgctac tccatgaatt ggttttgctt
    68521 taaatgtaac ttctagtcca tgtgatgtaa atacatcttc tataacatct cttactaata
    68581 actcattatc tgctgcttgt aatggtgtag aaaacttcca agaaacctct aattgctcca
    68641 tagcatggtt tgttcttcca tctatactaa tagaactttg tattcctcca acctctttgt
    68701 gagccatttc agggcttaca cctagttttt gaagtataat taaacttttc tctaaacaag
    68761 ttcttataat accatgagtt cttttccagt attgctcttt taggctttgt gatacatata
    68821 atttctctag gtcagcttta tcttcaggag tattaaccca gaactcaagc tctgtagctg
    68881 ctgttaacat tatttcctct atatcatcta ctgaatctat tcctatgtta tttattacat
    68941 gtggatattc tctaaatatt tcatacattg attttttaaa atacttatct gctttttgaa
    69001 gtactcctct agaacatact tttttattat catgtattaa aaatgcaggt atctttaatg
    69061 ttccaacagg tagacctact tcttcgtcta tatattccat attataatct acataccaat
    69121 gacaactttt atccggcatt aaatctactt ttgcattatt taatgtagct atgttataaa
    69181 gctcaacact tgaaccatca gtctgtatag ctgattccaa aaacttatct atgtcatcca
    69241 aaaataattc tacaggaatc ttttcatctg ttgcattgcc tcctaaatca acccccatta
    69301 aggaaacaaa tcttatattt ttattgcttt ttaggatttc tcttaattct tcattagtat
    69361 gtttatcttt ctctattacg tataatagac tatccatttt tccactctcc cataattttt
    69421 atgtaaattt tattttgtta aatacaagat aaatttcatt ttccttacat ttatgaattt
    69481 ttcttgcaaa ttattcgtgt tttattcgtg tttttattta tattattata tatcaagtac
    69541 aaaaagttcg caatattttt tattggaaaa aatattatac atacaatagt ttaacatttt
    69601 tataaatatg gggtatacta aaataaaagt atttttattt gaaaatttaa ttttatttat
    69661 aatataatct atagtaaaag aaataataaa aaaatttagg agataaactt tatggaatac
    69721 ataattttcg atttagaatt taatcaagga tttgataaaa aattcaataa aactatatcc
    69781 aatgaaaagt gtccttttga aattatacaa ataggagcaa ttaaattgga ttctaaattc
    69841 aatataatag atacatttaa tagctatgta aagcctacga tttataaaga aatacatcct
    69901 tttattagtc gtatgactaa tattaaagat tctgatttta atgattcgcc tactttccct
    69961 gaagtttaca acaattttat aaaatttata tcatcacaag accctatatt atgtgtctgg
    70021 ggagctggag atttaaagga attatacagg aatatcaact accacaaact accatcaaat
    70081 tccttaccta aatcttatat taatatacag caacatgcat ctaaatattt taataatcca
    70141 gcaggaaaaa gcattggatt acaaaatgct atttctatat tggaacttga tgaaaaaatg
    70201 tcttatcaca atgctttaaa tgatgcatat tatactgcta aagtttttat taagatatac
    70261 aatccaagta tagtaccaga tatatatctt tatacaagta tcaaacctaa aactataaga
    70321 tattccaata aaaaaagagt tgattatgat aagttatttg atgagtttag gaaaattttg
    70381 aatcgtgaat tgactaaaga tgagaaaaaa atcattaact tagcttataa catgggaaaa
    70441 acaaatcaat ttatattaga agatgctaaa caaagaaaaa acaaataaag tttacttagg
    70501 ttaaaaatag gcatgtagat taaataatta gttagcttta aatttatatc tacagcccaa
    70561 tttttatcct aattaatctt tattttattt ctaactcaac tggacaatgg tctgaaccta
    70621 atacttcagt gtgtatatct gcacttatca atctatcttc taattttttg gatgcacaaa
    70681 aataatctat tctccatcct gcattatttt ttcttgcatt aaatctatat gaccaccaac
    70741 tatagacacc ttctttatca ggattaaaat atctatatgt gtctataaac ccactatcta
    70801 ataatttaga aaacttctct ctttcttctt tagtgaaacc tgcatttttc atattatttt
    70861 taggattttt taaatctatt tctttatgtg caacgttcat atctccacac acaattacag
    70921 gcttatgatt atctagtttt gttaaatagt ctataaagtc gtcttcccat ctagttctat
    70981 attctagtct ttttaattca gattgagaat ttggtgtata cactgtaaca aagtaaaaat
    71041 cttcaaactc tagagttatc actctaccct ctttgtcatg ttcttctata tttattccat
    71101 acattacttt taaaggctct ttttttgtaa atatagcagt acctgaataa ccctttcttt
    71161 cagcataatt ccaatattga aaatatcctg gcaaatccaa ctctatttgt ccttcttgta
    71221 atttagtttc ttgtaagcaa aatacatctg catcgacttc tttgaaaaag tccaaaaatc
    71281 ctttcccagc acaagctctt attccattaa cattccatga tataaatctc atactatact
    71341 cctcatctaa acagtaaatt tcttgttatt cttcatttgc ttttatttta acaataatat
    71401 actataattt catctaaaat tactatttac ttaataccta aaaatatatg ttttaatcaa
    71461 ttttcaactt ttttgttagc tcttcaggac tcattgaaga aacatacatg tttgttccaa
    71521 gttcaaatcc tccaaaattg tattttcttg ggattatgtg catatgaaca ttaaaatacg
    71581 attttgtttc aatctttgtt ggatgagtgt gaatacataa gttaaatggc atatatccat
    71641 tgatattgta caatttctta aacaactttt caaatattgt agaaagttcc tttatattat
    71701 tatcatttaa ctcaccaaac tttattttat ctttaaatat tattcttact tctccactat
    71761 acttggttgc atatggtata atcactaaaa aagcttctcc attataaaca actcttctat
    71821 ttaaacttat ttcattttct attaaatcat catacaaaga gcttttattg ctgtcataat
    71881 actcctttga aactaacagt tcattcgtaa tttcaggagg aataaaagac atagacaata
    71941 tttgagcatg tggatgcatc aaagatgctc ctgcctttct taagaagttt ttgaagatac
    72001 taacatactc cactttatca tctttggaca aatctctaaa tctatttcta tacataaaaa
    72061 aaacatcttc aaattctttt tgactcatgt tataaaaact acgattatgt ttactgctct
    72121 ctatcattac ttcatgaaca ccatatatgt ctcttgccat atcatcaatt atagggaact
    72181 tattgtagac agattttaca agccatcctt cttcaccttc tatttcaaat aatgcatcag
    72241 ttgcataagc ttcatttcct ttgcaaaatg gacattcttt atcgtattca ttagtttctt
    72301 catcttcatt tggtatatct gctgtatcta aaggtctttt taacctatca gtagcaaata
    72361 taacaacatc attggtaatt ggatctattc ttaattcttt catagttaac acctcttagt
    72421 taatagcctt taatataatt atatgatatt tatcgtatct gttaaataaa tttataatat
    72481 tttttataat tttgcatatt tattattata tattttgtct atagctgaaa gattataact
    72541 aaaaaattac tatcagtgta tcagaatatt atcttaccat aaattaattc ataaatacat
    72601 aatttagtgg cataaacatg ggtatttaac tataatttgt taaaagttta ttttaaaact
    72661 atattaattt tttttgatga tttttaccca taagtatgtt attattatct tgtaaagatg
    72721 tcttgtattc aaacatacaa tttacataat acaatatacg tatttaaatt aaataggggg
    72781 tattaaaatg aattattcaa acagagttag tgcaatgcaa gcctctccaa tcagaaaact
    72841 tgttccattt gcacaagcag caaaagataa aggaatcaaa gtatatcact taaacatagg
    72901 acaaccagac ataaaaactc ctaagggatt ttttgatgct gttaaaaact ttgatagcga
    72961 agtcttagaa tatgctacat cagaaggtat tccagaatta ttagaagcac ttcaaaatta
    73021 ctataaaact tacaatatga attttgaaaa agatgaatta ctagtaacta atggaggtag
    73081 tgaagcttta cttttcacta tgatggcagt ttgtgaccca ggagataatc tattagttcc
    73141 agagccattc tacacaaact acaatggatt tggtcaatct gtaaacgtag aagttaatgc
    73201 tgttacaaca aaagcagaaa acggtttcca ccttccatct aaagaagaaa tactgtctaa
    73261 ggtagatgat aaaactaagg ctataattct ttctaaccca ggaaatccaa ctggtgcaat
    73321 ttatacaaaa gaagaactta atatcctagc tgaaatagct aaagaaaaag atttatggat
    73381 aatagcagac gaagtttata gagagtttgt ttatgatggg cttgagtata caagctgtgg
    73441 taacttagag ggtgtacagg atagagttat aataatagac agtgtttcta agagatacag
    73501 tgcttgtggt gctagaattg gttctatcgc ttgtaaaaat aaaggtctta tagctcaaat
    73561 acttaaatta tgccaaggaa gactttgtgt tcctacatta gagcaaatag gagctgttga
    73621 attatataaa actcctgttt cttacttcaa agaagttaat gaagagtaca aaaaaagaag
    73681 agatgtatta tacaatgaat taatgaaggt tgaaggagtt atatgtaaaa aaccaactgg
    73741 tgctttctat atagttgcta aattaccagt tgaaaatgca gaagacttca caatttggat
    73801 gttaaaagaa tttaacaagg ataatgaaac agttatggtt tgccctgctg aaggattcta
    73861 tgctactcca ggtttaggac gtgatgaaat aagattagct tacatcctaa atgaaaaaga
    73921 ccttcataga gctgctacat tattaaaaga aggtttagag caatatgtag ctttacaaaa
    73981 ataatttttt aaaattaatt tatataaatt taatgataaa aaatatcccc ttttcagata
    74041 ttatttgaaa aggggatatt ttttatagag attataaaaa agcacatcaa gaaaatttaa
    74101 gatatacttt ttagattgta tttagattta taattatata gctaaattca taacaaaaag
    74161 ttaatcttaa tactattaaa tataaaaatt tttgtatttt ttctatctaa attcttcttt
    74221 gttcaatata tattgaagag tatttattgc ttctaaatat ttttttctgt cttcttcagt
    74281 taatttagaa agtttttctc ctaaaccatc acttaactta tccataaaat cagttgctat
    74341 cttatctccc tcttcagtaa tatcaattag atattttctt ctatcaacta aatctctttt
    74401 tcttgttaca tacttcttat cagttaaatc atcaaccata ctagttaaac tgcctttttc
    74461 tatatttaac ttagagcata aatcagtcat acttattact ccataatttt ttatgaaaac
    74521 taatgctctt aattgtgttt tatttacatt ataatctggt gcaaattttt ttaggtcttc
    74581 taaatacagg ctagaataaa tcttaggaaa tgtttttact aaaaaactta tggtatcttt
    74641 tactatatag ttcatataat cacctcggtt gttttaaaat ttattaaatt atctaaataa
    74701 ctttatttca gtttacatta aaaatattgc aagtacaata gtttttgctg aatgtttaaa
    74761 tttaattagt aatcttatca ttttttattt ttatttatat taaatactat ttatatagct
    74821 attttattaa attcatggta tagtaagtaa agaagaactc ttcacagcgg tgaagagaag
    74881 acgctagccc attaaaacgg ctatcttatt tataaataag atagccgttt ttaattatat
    74941 tttatctgta taattctata cccttaagtc tacatctact tttcctaagt cttctttata
    75001 atcttttata gcaggttcta caacttcatt tacaaactct acaacttgtt ctggagctct
    75061 acctataaag ttttttgggt ccattataga taatatttct tctttgctca tcttaaatga
    75121 atcatcattc attataagtt caatcaaatt attatcctta ccttcatgtt ttactctata
    75181 ggcagctttc atagaatatt ctcttattat ttcatgtaat tcctgtctat ctccacctct
    75241 ttttacagct tccataagta ttgtttctgt agccataaaa ggaagttctt catttacacg
    75301 tttatttatc atattttcat atactactaa accatcagtt acatttatcc ctatttcaag
    75361 tatagcatct gctgccataa atgcttgagg tattgccaat ctcttattag ctgagtcatc
    75421 taatgttctc tctaaccatt gagtagcttg taccattgca gggcttatag actcagagat
    75481 tatatactta gataaagatg ctattctctc acttctcatt gggtttctct tataagccat
    75541 tgctgatgaa cctatttgat ttttttcaaa tggctcttct aattctttta aactttgtaa
    75601 aagtcttata tcattagtca ttttatgcat actttgagct atgcctgata atatgcttac
    75661 tacttgataa tctaactttc tagtatatgt ctgtccactt actgcataag aagaattgta
    75721 tcccatcttt ttgcaaattt tcttatctaa ctcttttact ttttcatggt ctccttcaaa
    75781 taagcttaaa aaacttgctt gagtaccagt agtaccttta actcctctta acttcatatt
    75841 atctattcta tagtttaaat cttccaaatc aagaattaaa tcttgagccc ataaacaagc
    75901 tctttttcct actgttgtaa gttgagcagc ttggaagtgt gtaaatccaa gtgctggcat
    75961 atctttgtac ttaagtgcaa attcttttaa attgtttatt aaatttacaa gctttactct
    76021 tagaagtttt aaagcttcat tcatttgtat aacatctgta ttgtctccaa catatgcaga
    76081 cgttgcccct aaatgtatta ttcctttggc tttttcacat tgtaacccat aagcttttac
    76141 atgagacatt acatcatgtc ttacttcttt ttctattttt ctagcttcat caaaatttat
    76201 attatctata ttagctctta gctcatctaa ttgttcttca gttatattga ttcctagctc
    76261 atgttcacct tctgcaagtg caacccataa cctcctccat gtagagaatt taaattgtgg
    76321 agaaaatata taactcatgt ccttgctaca atatctatct gtaagtgggt ttgaataagt
    76381 agtatattta ttatctatca ttatattagc accttcctta aatcttttgt cgtatgatta
    76441 ctgtgtacac attagtacat aaataattat atataatttt acgaactata acaagacttt
    76501 tttatttttt gttcatattt atatagtgtt ttttatttat taatattttt tatttatatc
    76561 caaattatcc ttttcaatta agtaatccac tatttcacta tcaacaaaat ttaatacata
    76621 cttatatcta attgcatagt atttatcact ccatccaagc tggtttttta catcgctctc
    76681 atctgcccca agccttaaac ttattgctgc aaatgaatgt ctaaaatctc ttgctgaata
    76741 ttgagaaagc ccagctaaat ctaatgcttt tttgactata agtctgacat ttctatctgt
    76801 tatagaatta ctcttttgag ttgtaaaaat aaaatcatca ctaggtatta ttacctctgg
    76861 aagcccagaa taattcctgt aatcttctaa aagtttaaaa aagtatggat gtaatttaac
    76921 tactctttct tttcttccct tacctaatct tacatatgag ttatcgtttt catctaccat
    76981 aaggtctttc cactttaagc taactaattc atttaataaa cacccagtag taactagaca
    77041 gactattatt actctatctc ttatatttaa ttttggtagg atacctataa gtttatttat
    77101 ttcttgtata cttagaacgt catcttttgt ttttattctt gttactgttg gtttttctac
    77161 atatctaaat ggatttatat ctatgtatcc ttcttttttt aagaagttat aaaaactatg
    77221 taaataacta tatatctttt cacaagttga tttcgcatat ttagtctgta tataatctac
    77281 aaaattttta caatcttctt ttgtagcata aatcaattcc ttccctttta aaaactcttt
    77341 aaacagtata acctttgata aataatcgtg ttttgtgttt ggatttaatt ttgtagaaaa
    77401 aacattaaaa gtttcatact cataatcatc tagtattttt gtactataca taataactcc
    77461 tttccttttc ataaaataaa ataactatac ttttactata ccatatattt ccccctcaaa
    77521 tatacccctt attcaaggga tgacttttaa gtttattttg ttatattatg aaggttttat
    77581 gaaaatgtca atcttccatt gtgcactaca cagtactatg gtattataag ttagtaaaag
    77641 gtggcatttt tttattaata tatgaataaa atatgctact ataaatttgt attggaggta
    77701 ttttggtttg gaaacattta gtttgcttga aatttttaag gcagtcattt taggaatagt
    77761 tcaaggaata acagaatggc taccagtaag tagtacaggg catatgatat tagttgatga
    77821 gtttataaaa ttgaattttt caaatacatt tataagtaca tttttagttg taattcaatt
    77881 tggttcaata ttagctgtac ttgttatatt ttttagaaaa ttaaaccctt ttgatagtgc
    77941 aaaaaatatt aagcagaaaa aagaaacagt tcgtttatgg cttaaggtta taattgcagt
    78001 tataccatct ggagttattg gaatactgtt tgaagatgat atagatagat tattctttaa
    78061 ttcaacagta gttgctattg ctcttattgt ctatggtata ataatgatag ggcttgaaaa
    78121 gagaaataaa agacctaagt ataaagattt ttctcaagtt acatataaat tagctctttg
    78181 tataggatta ttccaatgtc tagctcttat accaggtaca tctaggtctg gttctactat
    78241 aataggtgca gtattacttg gtacttctag atatgtagca gcagagtttt cattcttctt
    78301 agctatccct acaatgcttg gagctagtgc attaaaactt ctaaaagctg gatttggatt
    78361 tactggattt gaatggctta ttttaggtgt tggttctgtg gtagcatttg ttgtttcaat
    78421 tgtagttatt aaatttttta tggactatat caaaaaacat gacttcaaag tatttggtta
    78481 ttatagaata gtcctgggta tagtggttct tgcttatttc tttctattat aatgtattct
    78541 aatttaataa caaatgataa ggagaaaagt tatgagtgtt aaaaaagaaa tatttgattg
    78601 gattaagtca atagctatgg ctattgtact tgcatttgta attctacaat ttataagacc
    78661 ttctattgtc agtggagaat caatgtatcc tactttagat gataaagatt acctaatttt
    78721 aaataggata tcatacaaag ttggtaaacc tgaaaaaggc gatattgtag tttttaaaac
    78781 caatttagtt gatggagaaa caggaaagaa aaaagactta ataaaaagaa ttatagctac
    78841 tgaaggtgac agaataaaaa tatcaaattc taaggtgtat gtaaatggaa aattattaaa
    78901 tgagccatat atacataata actatacttc tggagatata gatactgttg ttccaaaagg
    78961 taaaatattt gcaatgggag ataatagaga aaatagtaat gatagtagat ttcctgatgt
    79021 aggtatgatt gatgaggatg aaattcttgg taaggttatg gtgagactat tacctcttga
    79081 taatattgga aaagtagatt aaaaaaaaga gactgaattg gtaaaattta ttttacaaat
    79141 ctcagtctct ttttatttac ttaaattaaa aatatttttt actaaatatc ttttgattct
    79201 gtaataagtc ttattatatc acttgcttct tcattaaaag ttgttactat acttaagtag
    79261 tctgttgctc tactcatagc taaataaacc ttatttaaat ctcctacaaa atcatttact
    79321 tgataatctt gctcaatatc atttatagtt tgattgtata acatttctaa ttcacatact
    79381 attactgctt tatattctaa attctttatt gcatatatat ttgctattgt agttcctacc
    79441 ttcttactta tatttgttaa gttatcttct gcacatatat aaggaatttt tgcctcttct
    79501 aatgcttttt ttaacatata ctggaaataa atagtttttc cactttttaa tttcttctta
    79561 ttataaggat aaacaatagc aacttcggaa taatcaagac cttttttact tattaaatac
    79621 tcaatttccc atattacaga acttatttgg tcatcaaggt cacttacttt tattatatca
    79681 acagacttat ttccacctct aagtgcttta gtataaaaga aagtactaaa ttctgtattt
    79741 ggtcttaatt cgttgatata tgagttagaa ttatttgaaa atttatttgt aaaatctaca
    79801 atctctttgg cttgtctata atttttactt aagataatct tatcatcaaa ttctatacca
    79861 ttatataact ttttaaatat atttaatcta ttagagatat tcaaagagtt acaagaacac
    79921 acattaaata taaattttgt tttatataaa aactctctta taaaatctat ttcatactct
    79981 aaaaagcttt ctgcttcatc tataaaaata gctttaaaca tatttttatt ttttataatg
    80041 ttctgtgctt gttttacaag attattaaac gccttttcgt aatcattttt taacatgtta
    80101 tagtctacaa ttaaattgaa ttttttagct agtttaaata taaaagaact aaatgtgtga
    80161 acttctaaat tattattatc tttatataac aactctatcc tctctctaag ctcattgcgc
    80221 aattgttttg tatgtgtaaa tatgattaat ttatgatgtg gatatacttt tgctaatttt
    80281 atagctctag aaagcataat tgctgtttta cctataccag agccaccttc aataagtgta
    80341 ttcccatatt taatagaaat aacatcttta atttgaactt cttccatcat agttgctgta
    80401 tacttatagt catcattgta gaatgaaatt tttttaaatt tttcatttaa atgaagtttg
    80461 tcatttatta tatagtattc tgaacataca tctaataaaa ataaatttaa gtttatctca
    80521 tcattctcat cattaagata ctcatccagc gaacctttat tcattatatc ttgaagctta
    80581 ttcttatcta ttatattgtt attaacaaat tcttcaaatt catatgtttc ctcaacttca
    80641 acgtatggca taatgtaaac gtagttataa cttatatttc tattcttttg tcccattttt
    80701 agtttcaaaa gttcatattc ctcattcata acttcaagta actcttcttc taaaataaaa
    80761 aatatatctt ccgttgtatc cataaatttt ataaataaaa tttttccatc tttaacatac
    80821 aacaaatcgg tatttattcc tttaaaagga gtaacttttg gcactacttt aacgtcctta
    80881 ttgatattct cgtaaaatat tttctcaaat tctttcaatt ttagggcgtc taactgagaa
    80941 tttatattta tgtattggct cacttacatt acctccttct gttatactta attataccat
    81001 tttgaactat atttttatat atacttttta taggcaaatt tagtaaataa attcaaaata
    81061 aatacaaata aatacaaaac agctaaaaaa attttgcaat aagtacagat atttattgtt
    81121 atagaatatt ttatgtaaat agtaaaatga tgaatttcat aattaatact tacaa
//
LOCUS       DBGJFK010000010        72651 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.010, whole genome shotgun sequence.
ACCESSION   DBGJFK010000010 DBGJFK010000000
VERSION     DBGJFK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.010"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(131..325)
                     /locus_tag="ACOIAP_000854"
     CDS             complement(131..325)
                     /locus_tag="ACOIAP_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637763.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFENTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(634..2163)
                     /gene="lysS"
                     /locus_tag="ACOIAP_000855"
     CDS             complement(634..2163)
                     /gene="lysS"
                     /locus_tag="ACOIAP_000855"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGZ2637764.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMEIKDNFESLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNAEDPRRTDRFEVFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2178..2657)
                     /gene="greA"
                     /locus_tag="ACOIAP_000856"
     CDS             complement(2178..2657)
                     /gene="greA"
                     /locus_tag="ACOIAP_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGZ2637765.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2766..3734)
                     /gene="dusB"
                     /locus_tag="ACOIAP_000857"
     CDS             complement(2766..3734)
                     /gene="dusB"
                     /locus_tag="ACOIAP_000857"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGZ2637766.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEDEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3871..4641)
                     /locus_tag="ACOIAP_000858"
     CDS             complement(3871..4641)
                     /locus_tag="ACOIAP_000858"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HGZ2637767.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIINMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4660..5250)
                     /locus_tag="ACOIAP_000859"
     CDS             complement(4660..5250)
                     /locus_tag="ACOIAP_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGZ2637768.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGGAIGFIFGISSLLNAIINPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5444..6403)
                     /locus_tag="ACOIAP_000860"
     CDS             complement(5444..6403)
                     /locus_tag="ACOIAP_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HGZ2637769.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMIQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGNFKCRPDLKMGYRACEVANIDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKAIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKK"
     gene            complement(6396..7373)
                     /locus_tag="ACOIAP_000861"
     CDS             complement(6396..7373)
                     /locus_tag="ACOIAP_000861"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HGZ2637770.1"
                     /translation="MRDKIVEIMLNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNICYKLDTEFIGKNIEHLETIDSTNEHAKRIAVN
                     SLDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNMGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IAEKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNKELVKCLDINEEGNLLVQRSDGNIKEIISGEVSIRGEKGYV"
     gene            complement(7687..9657)
                     /gene="ftsH"
                     /locus_tag="ACOIAP_000862"
     CDS             complement(7687..9657)
                     /gene="ftsH"
                     /locus_tag="ACOIAP_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGZ2637771.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9691..11079)
                     /gene="tilS"
                     /locus_tag="ACOIAP_000863"
     CDS             complement(9691..11079)
                     /gene="tilS"
                     /locus_tag="ACOIAP_000863"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGZ2637772.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERSEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVSEE
                     IEFYYNIPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11262..11675)
                     /locus_tag="ACOIAP_000864"
     CDS             complement(11262..11675)
                     /locus_tag="ACOIAP_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGZ2637773.1"
                     /translation="MSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVVYKEKE
                     ENIEITNTIKILKNEVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDTRKLDI
                     NIQEGEHIKLKIDYNINVQDLFLGRNKIDIYIDTK"
     gene            complement(11707..12513)
                     /gene="murI"
                     /locus_tag="ACOIAP_000865"
     CDS             complement(11707..12513)
                     /gene="murI"
                     /locus_tag="ACOIAP_000865"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGZ2637774.1"
                     /translation="MSNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKV
                     LEVKNIINNTEIHGTYQYYVSDIPEKFTDIAREFLKKKIDRIQKVEIQKY"
     gene            complement(12715..13200)
                     /locus_tag="ACOIAP_000866"
     CDS             complement(12715..13200)
                     /locus_tag="ACOIAP_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HGZ2637775.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTAKIEKINKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13251..13910)
                     /gene="spoIIR"
                     /locus_tag="ACOIAP_000867"
     CDS             complement(13251..13910)
                     /gene="spoIIR"
                     /locus_tag="ACOIAP_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HGZ2637776.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILENGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVIEVVKDLEKK
                     F"
     gene            complement(14056..14736)
                     /locus_tag="ACOIAP_000868"
     CDS             complement(14056..14736)
                     /locus_tag="ACOIAP_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2637777.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISEEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14720..15610)
                     /gene="ispE"
                     /locus_tag="ACOIAP_000869"
     CDS             complement(14720..15610)
                     /gene="ispE"
                     /locus_tag="ACOIAP_000869"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HGZ2637778.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELEEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNQLWKLRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTSIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTISKHKEISDIKQIMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15728..17278)
                     /locus_tag="ACOIAP_000870"
     CDS             complement(15728..17278)
                     /locus_tag="ACOIAP_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOCS domain-containing protein"
                     /protein_id="HGZ2637779.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17371..17637)
                     /locus_tag="ACOIAP_000871"
     CDS             complement(17371..17637)
                     /locus_tag="ACOIAP_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGZ2637780.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17785..18645)
                     /gene="yabG"
                     /locus_tag="ACOIAP_000872"
     CDS             complement(17785..18645)
                     /gene="yabG"
                     /locus_tag="ACOIAP_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HGZ2637781.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18729..19667)
                     /locus_tag="ACOIAP_000873"
     CDS             complement(18729..19667)
                     /locus_tag="ACOIAP_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGZ2637782.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMATKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLNKFYDLGVRMMTISWNHVNELSFPHNKLEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDEIEKIYYKNALRVIKEVL"
     gene            complement(19777..19938)
                     /locus_tag="ACOIAP_000874"
     CDS             complement(19777..19938)
                     /locus_tag="ACOIAP_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637783.1"
                     /translation="MFILRFADDDDNLSVKDFKSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19948..20445)
                     /locus_tag="ACOIAP_000875"
     CDS             complement(19948..20445)
                     /locus_tag="ACOIAP_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HGZ2637784.1"
                     /translation="MSLYTEWRNLSDNHENQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEDVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20560..21270)
                     /locus_tag="ACOIAP_000876"
     CDS             complement(20560..21270)
                     /locus_tag="ACOIAP_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HGZ2637785.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNNVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWIKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYNVDINNIKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFGLDVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     DQEYAIKVLKELFNYDII"
     gene            complement(21443..21973)
                     /locus_tag="ACOIAP_000877"
     CDS             complement(21443..21973)
                     /locus_tag="ACOIAP_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637786.1"
                     /translation="MDIRALPTKITKEEAIDIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIVTLKIHKTKSIFKSRRYSNGVNELKILVNGSTGSGSIVQDFPTYEIIKNVDCN
                     IVQYSDKDERRVKAKANKIAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21990..22220)
                     /locus_tag="ACOIAP_000878"
     CDS             complement(21990..22220)
                     /locus_tag="ACOIAP_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637787.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGRIIPYGVMAVVIIIFFDYIYRVSKMTRKK"
     gene            complement(22235..23629)
                     /locus_tag="ACOIAP_000879"
     CDS             complement(22235..23629)
                     /locus_tag="ACOIAP_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HGZ2637788.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWRIDKELIGLIMVGI
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23755..25008)
                     /locus_tag="ACOIAP_000880"
     CDS             complement(23755..25008)
                     /locus_tag="ACOIAP_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HGZ2637789.1"
                     /translation="MENKSNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALSLS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGALGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGLLLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKSLNNKIA"
     gene            complement(25059..26213)
                     /locus_tag="ACOIAP_000881"
     CDS             complement(25059..26213)
                     /locus_tag="ACOIAP_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGZ2637790.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKDAMKPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEEKVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26774..27346)
                     /locus_tag="ACOIAP_000882"
     CDS             complement(26774..27346)
                     /locus_tag="ACOIAP_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637791.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFARKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSIQ"
     gene            27549..27776
                     /locus_tag="ACOIAP_000883"
     CDS             27549..27776
                     /locus_tag="ACOIAP_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGZ2637792.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(27996..28739)
                     /locus_tag="ACOIAP_000884"
     CDS             complement(27996..28739)
                     /locus_tag="ACOIAP_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HGZ2637793.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEQEYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILSLMGFANNFGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDSGIVIYFGVDEIAPESFGIPKFKLKFSD
                     FGNFINSRFYCISPDIYVQSRGRVKYFMG"
     gene            28906..29778
                     /locus_tag="ACOIAP_000885"
     CDS             28906..29778
                     /locus_tag="ACOIAP_000885"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2637794.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGNYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGYIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29778..30443
                     /locus_tag="ACOIAP_000886"
     CDS             29778..30443
                     /locus_tag="ACOIAP_000886"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGZ2637795.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKNHKDAKEAELNYNVLNFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEIYHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30464..31321
                     /locus_tag="ACOIAP_000887"
     CDS             30464..31321
                     /locus_tag="ACOIAP_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2637796.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIGLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSAKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKYITEISAGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31458..34004)
                     /locus_tag="ACOIAP_000888"
     CDS             complement(31458..34004)
                     /locus_tag="ACOIAP_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2637797.1"
                     /translation="MNIFNKVALQGLKKNRTRTFVTIIGVVLSAAMITAVTTFGVSLM
                     NYMINGAIIKYGDWHVEFLDVDSSFVQEQRVNDEVENTVTFENIGYATLEGSRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSGKVATDGGVKFAVGDTISLDVGKR
                     MSENENLGQSDPYTAGSEAFIPQNKRTYTVVGICRKPVFEESSAPGYTLITKEDEQVK
                     ADSLSLFVTLKNPRHVRSYTSSAREHDYIFNDNVLRFMGISDNNLFNMFLYSVGGVVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGVIGIPIG
                     VVIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIVVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQQIYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVKDLKQMSNQRSEVTDQDIIFSTQGMKDSEMLKLYDKLKTASGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYNGLHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPTEEYTGQNAKMIAVSMLTKDNHIIDIFTNSSMDVSLTPEVNGKLDTPERQNVNIS
                     FVKVVPPDSPPGIRNSDMKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     SEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWVSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34004..34690)
                     /locus_tag="ACOIAP_000889"
     CDS             complement(34004..34690)
                     /locus_tag="ACOIAP_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637798.1"
                     /translation="MAFLKIENLCKVYGKNENQVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34773..35762)
                     /locus_tag="ACOIAP_000890"
     CDS             complement(34773..35762)
                     /locus_tag="ACOIAP_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2637799.1"
                     /translation="MFRNREFRRFAILFLLITILTVALGFAISTMTGIISIVSATTFG
                     TAFFVFTKNRYKSIAQISEQINLVLHNANHLYITESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIQ
                     MDWLITSLLKLSRLDAGIVVFQKEEIDVDNLISSALHQLLIPMELHNITLHINIPKGV
                     KILGDLNWLSEAIQNIFKNCMESVGDNGKIDIVCEDNFLFTQLTIHDNGEGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAENHPQGGAIFVIRFPK"
     gene            complement(35749..36435)
                     /locus_tag="ACOIAP_000891"
     CDS             complement(35749..36435)
                     /locus_tag="ACOIAP_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637800.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKENQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            36853..37182
                     /locus_tag="ACOIAP_000892"
     CDS             36853..37182
                     /locus_tag="ACOIAP_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGZ2637801.1"
                     /translation="MDLNKEVLKGHIDTLILSILNKGDSYGYEIAKIVINETTFELKE
                     STLYVSLKRLESKGLIKSYWGSDQGLGSRRKYYNITDEGKENLELKIQEWNFIQSVMN
                     KFLKRGE"
     gene            37187..37636
                     /locus_tag="ACOIAP_000893"
     CDS             37187..37636
                     /locus_tag="ACOIAP_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HGZ2637802.1"
                     /translation="MKIIEEYLEALYKNDTSKEIQDLKEELKEHLIDSTNEFIENGYD
                     INEAQNKAIERFDGSNGVSVELRSIFKQKIEPKKVLLRKLSNSRIVFLNLFGWLLAAT
                     AYTINRGFGHIAPPWIIILLIISIVILIILTIIIKGLKKEIENDYNI"
     gene            37703..38080
                     /locus_tag="ACOIAP_000894"
     CDS             37703..38080
                     /locus_tag="ACOIAP_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGZ2637803.1"
                     /translation="MVKKILLEKFLDTSGVSYINEKLNLFKDTKWISFGTYIMTVDSF
                     CYREDSKHYNPIMSTFDYESEIFIVNALYKENIYSIKSKKLYRNVSKGDKIIVTIKYS
                     YDKYENLIHEEIHDYHLYPLSLD"
     gene            complement(38265..41471)
                     /gene="carB"
                     /locus_tag="ACOIAP_000895"
     CDS             complement(38265..41471)
                     /gene="carB"
                     /locus_tag="ACOIAP_000895"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGZ2637804.1"
                     /translation="MPKLDNIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIAENEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHQLKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFSDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(41664..42713)
                     /gene="carA"
                     /locus_tag="ACOIAP_000896"
     CDS             complement(41664..42713)
                     /gene="carA"
                     /locus_tag="ACOIAP_000896"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HGZ2637805.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESIGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITVFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(42970..46176)
                     /gene="carB"
                     /locus_tag="ACOIAP_000897"
     CDS             complement(42970..46176)
                     /gene="carB"
                     /locus_tag="ACOIAP_000897"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGZ2637806.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIAENEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVAKELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(46229..47272)
                     /gene="carA"
                     /locus_tag="ACOIAP_000898"
     CDS             complement(46229..47272)
                     /gene="carA"
                     /locus_tag="ACOIAP_000898"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HGZ2637807.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKETIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     TENIKGTGAKVTVIDFGVKNSVLESLKACNCDITIVPAMTTAEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(47298..48014)
                     /gene="pyrF"
                     /locus_tag="ACOIAP_000899"
     CDS             complement(47298..48014)
                     /gene="pyrF"
                     /locus_tag="ACOIAP_000899"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGZ2637808.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDKLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     VAKEEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKRGAHYLVVGRPI
                     TKAKDPRESAINIVREIENA"
     gene            complement(48390..49025)
                     /locus_tag="ACOIAP_000900"
     CDS             complement(48390..49025)
                     /locus_tag="ACOIAP_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HGZ2637809.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     KKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKVFEHH
                     GFEVFSVICKNGAIPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEARVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(49049..49963)
                     /locus_tag="ACOIAP_000901"
     CDS             complement(49049..49963)
                     /locus_tag="ACOIAP_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2637810.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKSFEEDEEDDLDYLVGIKTEEEDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKKPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEEIQEENVSLEKEELQDE"
     gene            50565..51794
                     /locus_tag="ACOIAP_000902"
     CDS             50565..51794
                     /locus_tag="ACOIAP_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGZ2637811.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLSDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNKNLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPEGHVWLSGASKDPNGVSFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDKYGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGDWAF"
     gene            complement(51999..54380)
                     /locus_tag="ACOIAP_000903"
     CDS             complement(51999..54380)
                     /locus_tag="ACOIAP_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HGZ2637812.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGIQNPEKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSEYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVESPTVVGERLNPTGRKALQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLKSILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVDRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAIAMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNECSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKLDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDKI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(54352..55077)
                     /locus_tag="ACOIAP_000904"
     CDS             complement(54352..55077)
                     /locus_tag="ACOIAP_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 dependent-methionine synthase
                     activation domain-containing protein"
                     /protein_id="HGZ2637813.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKDTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNIVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSDLTKGLIIDSCGTTAIEEVCDIVQDNVEKVFLKQNKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISDTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(55067..55522)
                     /locus_tag="ACOIAP_000905"
     CDS             complement(55067..55522)
                     /locus_tag="ACOIAP_000905"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGZ2637814.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(55804..56985)
                     /locus_tag="ACOIAP_000906"
     CDS             complement(55804..56985)
                     /locus_tag="ACOIAP_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2637815.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLIVTSMYIIKSLYFNGAI
                     SVINQLVYQLRDFRSLIGESLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDNEKDDIDELAYKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVISQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGLYVDIVTEKKGDIAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHGGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(56975..57667)
                     /locus_tag="ACOIAP_000907"
     CDS             complement(56975..57667)
                     /locus_tag="ACOIAP_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2637816.1"
                     /translation="MKNTILVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMVLDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIEVGAVIIDKEKHSVTVAGNDIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(57801..58517)
                     /locus_tag="ACOIAP_000908"
     CDS             complement(57801..58517)
                     /locus_tag="ACOIAP_000908"
                     /EC_number="3.4.17.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HGZ2637817.1"
                     /translation="MKKFKLIVAIILVVFISVFISKDRLLKKDKEPTVIAQHYSKQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            58643..59377
                     /locus_tag="ACOIAP_000909"
     CDS             58643..59377
                     /locus_tag="ACOIAP_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis TtcA family
                     protein"
                     /protein_id="HGZ2637818.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRKEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(59662..60417)
                     /locus_tag="ACOIAP_000910"
     CDS             complement(59662..60417)
                     /locus_tag="ACOIAP_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGZ2637819.1"
                     /translation="MKKYNISENGTLIKNDIIESKSESIKVVQISDTQIGSFYSTKNL
                     KKVANKINTLNPDIIVFTGDLIDYSNKNPNVDEITTILSSMNARLGKFSVFGNHDYMY
                     KLPRYYRQIMKNSDFNLLVNENKKIKLKDNKYINILGVDEILNGHPNIKYLESQIDNK
                     NFNLLLAHEPDLVDMLSKYTMNLVLSGHSHGGQIRLPIKGALVTPPYGRKYTKGFYDI
                     NGNHLYVSSGLGSTKLPFRFFNIPEIIEFNIII"
     gene            complement(60539..61477)
                     /locus_tag="ACOIAP_000911"
     CDS             complement(60539..61477)
                     /locus_tag="ACOIAP_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGZ2637820.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYKGFK
                     KHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDSLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFVINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEVIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(61580..62230)
                     /locus_tag="ACOIAP_000912"
     CDS             complement(61580..62230)
                     /locus_tag="ACOIAP_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2637821.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIEEDLENLE
                     QFIGPPLYDTFKEYYKFEDKKAKEAVEKYREYFTDKGIFENKIYENIKEILEMLYKKG
                     KILLVATSKPTVFAETILRYFDIDRYFKYVAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYLVENVESIKDILL"
     gene            complement(62380..62568)
                     /locus_tag="ACOIAP_000913"
     CDS             complement(62380..62568)
                     /locus_tag="ACOIAP_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGZ2637822.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(62675..63859)
                     /locus_tag="ACOIAP_000914"
     CDS             complement(62675..63859)
                     /locus_tag="ACOIAP_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2637823.1"
                     /translation="MKNLLIRNGTIISPTDGIKFERRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPLNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNKNGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKKSGTLRKSVINAKDRGVLFDVCHGLDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHENKGRI
                     RIGGDGDFTIFTMEKSNDIIKDYNNNELILNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(63996..64913)
                     /locus_tag="ACOIAP_000915"
     CDS             complement(63996..64913)
                     /locus_tag="ACOIAP_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HGZ2637824.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTDTGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGKGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVVLEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(64935..65663)
                     /locus_tag="ACOIAP_000916"
     CDS             complement(64935..65663)
                     /locus_tag="ACOIAP_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2637825.1"
                     /translation="MLEIKNLSFNVESNSEELGIINDVSLSFEKGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESDQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(65859..66059)
                     /locus_tag="ACOIAP_000917"
     CDS             complement(65859..66059)
                     /locus_tag="ACOIAP_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637826.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(66184..66564)
                     /locus_tag="ACOIAP_000918"
     CDS             complement(66184..66564)
                     /locus_tag="ACOIAP_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGZ2637827.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRIFSFKDQDGNDYLVREDK"
     gene            complement(66837..68195)
                     /locus_tag="ACOIAP_000919"
     CDS             complement(66837..68195)
                     /locus_tag="ACOIAP_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2637828.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDNEKVNETIKQALVSGAILSFTITILM
                     WIFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIAIQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGVDLNPLGINLQTPSYGITGAAMSIAIARIIGCIVIVRAL
                     FKGNEFISIGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFVV
                     GAIFVPIAPWISSLYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     IA"
     gene            68479..68931
                     /locus_tag="ACOIAP_000920"
     CDS             68479..68931
                     /locus_tag="ACOIAP_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HGZ2637829.1"
                     /translation="MVNLNENNLNVNMVYPISPTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTIGLGTMNIDKVYGQWAWFTDTIYDLNLFVFVGNYPYQIAKNRYDTFVNILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(69087..69704)
                     /locus_tag="ACOIAP_000921"
     CDS             complement(69087..69704)
                     /locus_tag="ACOIAP_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HGZ2637830.1"
                     /translation="MEIFAIGHSNYPYDKLIDMIKKYDINCVVDIRETPYSKYNTQYN
                     KEAFNESLRNSGFVYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLKGIDRLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKILNKEGFDVKYIMHEGNLAYQQDIEESLLD
                     KYFADRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(70112..70924)
                     /locus_tag="ACOIAP_000922"
     CDS             complement(70112..70924)
                     /locus_tag="ACOIAP_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2637831.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKEAIENPEEVENILKNKEKEMLDVIKSEEYKLIKLRN
                     YLVNLKGEVNMNDVIIKSLPKVKIASMRKVLKGYDELFNLFPNVMAEEMMKSECTCAV
                     PDYCFNIYHDGEYRETNMDVEMCQAINDLKEDTDILKFKELDEVESAVCILHNGSYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRIL"
     gene            complement(71000..72418)
                     /locus_tag="ACOIAP_000923"
     CDS             complement(71000..72418)
                     /locus_tag="ACOIAP_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HGZ2637832.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GIFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIVPMVIKQIVFGLAIGFVLAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYIGGNGYLSVYISGIIIGNSKIPHKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNIFGIAMVISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVIIENDIFHIIFFIALLSVGVQGTLIPAVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDDSSKWANKSIMDSNIPEDILIVMIKRKEQVLVPKGS
                     TVIKTGDTLVLSGDRIEELIQL"
BASE COUNT        23083 a        13261 c         7884 g        28423 t
ORIGIN      
        1 atttcgtcaa tacttttttt gttttttatt ttaaaaaggt tataactttt tgtttttctt
       61 aataatttta attaaaacca atagatataa cccttgatat tacaaacaat acatgcatat
      121 ataattttac ctattttgca attttatttt cataagaata tgaattagct ctgactctat
      181 cagcccaaac atttatactc ttaactttat taacattagt tgtgttctca aaaatatcca
      241 ttgcatcctt acaaaaatat atcataacat caagaactaa aaatccaaca cagaataaac
      301 ataaaaaatt aatcacttga aacatcagac attcccccaa taatttttta tatatagtat
      361 tctcagaaat tattcttttt accttctcaa aaattattct aaatattttc ataataaatt
      421 actttcaatc atattttcta aatataaagt ctcaatcaac aaaaactaat atcaatttct
      481 aacgtttgtt ggtaatttat aaattaaata tctaaaagaa tctttgaaac atataaaaag
      541 cattctacac tgacatttta aataaagttt agctatttat tgctaattta atagctaaac
      601 tttatttaaa acttagtaga atgctaatat ttcttagttc tcttcttctt tatttggatt
      661 gttatcaata ggtttcatag tagggaataa taatacatct cttatagatg gagagttagt
      721 taataacatg attactctat ctatacctat tcctagtcct cctgtaggag gtagacctac
      781 ctctaatgct tttaagaaat cttcatccat ttcaaaagct tcatcatcac ctaattctct
      841 ttttctcaat tggtctataa atcttccttt ttggtcaata gggtcattaa gttcagaaaa
      901 tgcattagct aactcccact tattagcaaa tacctcaaat ctatcagttc tccttgggtc
      961 ttcagcattt ctcttagata atggagatac ttcaactgga tgatgagtta taaatgttgg
     1021 ttggattaat ttatcttctc caaattcttc aaagaaagca tttattactt ctcctcttct
     1081 cattccaggt tttatctcta tacctttttc tctagcaact tctaatgcct cttcatctgt
     1141 atttatagta gaaaaatcta caccagaata ttctttaaca caatcttcca tactcattct
     1201 tttccaaggt ggtgtaaagt ttatttctgt tccttgatag ttaactatca tacttcctgt
     1261 agcaacttca gccatatgcg caataacatt ttctgttatt tccatcatat cagtatagtc
     1321 tgcatatgct tgatataatt ctattgcagt atattcagga ttatgtttta aatccatacc
     1381 ttcatttcta aacattcttc ccatttcata aactttatca aatccaccaa caataagtct
     1441 ttttaaatac aattcatttg ctattcttaa atacattggt atatgtaaag tattatgatt
     1501 agttataaat ggtctagcgt ttgctccacc tgctatagta tttaatattg gagtctcaac
     1561 ttctaaaaat cctctatcat ctaagtatgc tcttaatgct tttaatgctt ttgttctaat
     1621 taaaaaagca ttttttactt ctggatttac tattaagtca acatatcttt gtctatatct
     1681 tagttcttgg tcttttaatc catgatattt ttctggtaga acttgtaaag atttacatag
     1741 taatactacg gatttagcct ttacagagat ttcacctttt ttagttttaa agatttcccc
     1801 ttcaattcca actatatctc caatatcata tgttgaaaat acactatatt cttcctctcc
     1861 tatagcatct agtcttacat aagattgaat tcttccctct tggtcttgaa tatctataaa
     1921 gccagctttc ccttgtattc tcttgctcat tatacgtcct gctatttttg tagttttgcc
     1981 ttcaagagat tcaaaattat cttttatctc catagaataa tgagttctat catatctact
     2041 ttctttaaaa ggatctctac ctgactcttg taattttttt agtttatctc ttcttacttg
     2101 aagtacttca ctaaggtctt cttgaatttg cgcttcttca ttgctttgtt gattattttt
     2161 catttttttc ctccaaatta tcttcttatt tctaatattt caaacttagc aactccatca
     2221 ggaacttgca cttccacaac ttctttcgca gctctaccta aaagtgcttt tcctacagga
     2281 gattcgtttg atattttacc atcatatggg tctgcttctg tcgaaccaac tatagtatat
     2341 tcaacctctt catcaaattc taaatcctta actttaacta ttgatcctat tgtaacaaca
     2401 ttaaggtcta ttttgctttc atctatgata acagcttttc taaccatatt ttctaatttt
     2461 aaaattcttt cttcaacttg tgcttgttcc tttttagctt catcatactc agcattttca
     2521 gataaatcac caaaagatat agcaactttt attctctctg caacttcttt tctctttaca
     2581 acctttaagt tttctaattc ttcttctaat ttatcatatc cctcttgtgt caataaaaac
     2641 tctttatttt cttccattat aaatacaact ccttcacaaa ttccttagga attttcctaa
     2701 ttatatttta aaaattttat aatctttttt taatttatgc gctatattat aagtcactat
     2761 tatttttatg tcaaggagtc ttccatatag tactccaatt tcgacacaac ttcttgatag
     2821 tcttctattt tgttaatttc atcccttaat tttgcagagt ttctaagtcc ttttaaatac
     2881 caagcgatgt gttttctcat ttcccttaca gctacatact ctccatgttc ttctactgca
     2941 agttttaaat gcttaatggc agtacttatt ttttcgttaa gagttggctc tggcaaaatc
     3001 tcgcctgtat tcatataatg gtttattctt ttaaatatcc aagggttacc ttgagcaccc
     3061 ctacctatca ttatagcatc acaaccagtt ttgtctaaca tatttattga atcttctatt
     3121 gtaaatacat caccatttcc tataacaggt atactcaaat ttttcttaat ctctgcaatt
     3181 atatcccaat ctgctttacc tgtataaaac tgttctctag ttcttccatg tattgctaga
     3241 gcacttattc cacaatcttc tgctatcttt gctatttcaa cagcatttac actattgtca
     3301 tcccagcctt ttcgtatctt taaagtcact ggcttttttg agttcttcac tactgccctc
     3361 aatacctctt ctgcaagctt aggatttttc ataagtgctg aaccatctcc atttttaact
     3421 acttttggag ctggacatcc catatttata tcgagaatct catttgaata atcattcatt
     3481 atctctgctg ctcttcccat aaactctggc tctgaaccga atatctgaac tgctacagga
     3541 tgttcttcat cttctatctt aagcattttt ttagtatttt catcatcata gcaaagtgcc
     3601 ttaccattta tcatttctgt atataaaagc ccacatccct gttctttaca aattaatcta
     3661 aatggaaggt ctgttacacc tgccataggt gatagaaaaa ctttattttt caattctaaa
     3721 tttcctattt tcattgtttt tctcctattt tttcctttat tttgtaattt aactttaaat
     3781 tcttatttcc tcattataat ataccacaca tatgtagaaa tctatcataa aaagggaatt
     3841 ggatatataa cccaattccc tgtatattaa ttattcttgg tttttttcat atattattct
     3901 caatccttct agtgttaaaa aaccatctac ataatctata cttttcgtct ctgaagcaat
     3961 cagtttagct aatccacctg tagctataac cttaacatca tcacaattca attctttctt
     4021 catcatattt attattttat caactaaacc aacatatcca taaattattc cagattgcat
     4081 agctgataca gtactcttac aaatagtcat acctggctta gctaattcta ctctaggtag
     4141 tttagacgca ctttgaaata aagcctcact agatattttt attcctggtg ctattgttcc
     4201 acctaaatat tcaccttttt cagagatagc acaaaatgta gttgctgttc caaaatcaac
     4261 aagtatactt ggtgctccat acttttctat acctgctaca gcattaacta ttctgtctgc
     4321 cccaacttgt tttggattat catattttat atttagacct gtttttatgc ctggacctac
     4381 tattaatggc tgttttttac agtactttat acaaaagttt tcaagagaat gcataacatt
     4441 tggaactaca gatgatatta taacatcatc aatatcactt atattcacat tatcataatc
     4501 aaatagatta cttatcaaga ttccatattc atcagaagtt ttttctctat ctgttttaat
     4561 tctccagtaa ttaactaatt tgtcaccttt atatatacct aaaaccatat tagtatttcc
     4621 aacatcaaat actagaagca tatgtcatta accttctttc tattttttgc ttttcttaag
     4681 tacagtggca acagcagcta ctactaaagc ccctactatt gcttctggca ctccatttgc
     4741 tgcggcaaga gccattatta cttttcctgc tgaaccactt ttacccattg catgaagata
     4801 cttgtcagca tataagacat atatcattcc taaaactcca gctgtattta acagagaacc
     4861 tatagcccct gtaattaaac ctgatatgta taccttgttt gtagccttaa ttattaactg
     4921 atatacataa taagccaata cacctatcat aactcttggt aatattgaaa ctaatggatt
     4981 tataaaaaca aaagatgtca ctgttgggtt tattatagca tttaagagac ttgatatccc
     5041 aaatataaat cctattgctc ccccaactat tggtccttcc ataatagctc caataataac
     5101 tggtatgtgc attatagttg cttttgtagg tccaactgga ataaatccca atggagtcat
     5161 agatagcata atagaaatag ctgatagtac tcctattata gtcatctttc ttacatttac
     5221 ttttcttact gatgcacttg tgttcatcat aaaaaataca cctccgttcc agctcattac
     5281 gatgccggac tacttaattt tttaaatttt tttcgttttt ttcttataat tatgagtcaa
     5341 gctaccattg taggatgccc gctctaacaa gaataatttt atcaagatga gttgccattg
     5401 tcaacaattt gacaagaaaa atatgctaat ttcatcatat ttctcatttt tttactatat
     5461 ctttatatgc cattatattt tctacactat ccgctttttt tactgcattt attatgcttt
     5521 tttccacaac ctctacagcc aatgaaccta ctaatgttat atctgcttct atttctcctg
     5581 ttgatattgt gaatattgta tccccatcat gaggtgtatg gataggaaaa atagctttag
     5641 catatccatc atgtcccatt tgagatatct ttttacatcc agctttagtt aacttagcat
     5701 ttgttgcaat tatcccaata gtagtattat ctacactaaa tccaccttta ctttcacctt
     5761 gtttcattaa tttatatgta tcaattgttt ctgtcttttt atcatttaaa gcacccgcta
     5821 taaccttacc attttcataa acatctccaa gggcatttac agcaattaat gcagatacga
     5881 ctagaccatt atctaatttt atagaataac tacctatgcc acctttcata gcatattctt
     5941 gacctcttat ctttccaaca gtcgctccac aaccagctcc ataatttcct tgatttaaaa
     6001 tgtcaatatt tgcaacttca catgctctat aacccatctt taaatctggt ctacatttaa
     6061 aattacctac tcctaaatca aatagaactg ctcctacaac tattggtact ttacctacac
     6121 ctacatcaaa gccaattcct ttttcttcta agtatctact tacaccacaa gtagattcaa
     6181 gaccatatgc agaacctcca gccaaaacta ctgcatgaac tttttgaatc atatttacag
     6241 ggtctaataa atcggtttct ctagtccctg gagcagaacc tcttacatca acaccacaag
     6301 tagctccttc ttcacatatt actactgtac acccagtaag accatttcta tcctcaactt
     6361 gcccaacctt taaaccttct atatccaaaa tattattata catatccctt ttctcctctt
     6421 atagaaactt cacctgaaat aatttctttt atatttccat cacttctttg aactaataaa
     6481 tttccctctt catttatatc taaacatttc actagttctt tattatctcc ttttaataca
     6541 tatatatttt tgtctataat tgcagaataa tctctacata tttttaaggt tttttctttg
     6601 gaattattta cagtataatc taaatataat ttttcaaatt cagtcaatac attcctaaca
     6661 atatctactc tggataacat gtatccttct ttatacaatg atgtagcttt ttcagctatt
     6721 tcttgttcaa aatccattat tttaacattt attccaattc caagaacaac gtagtttgtt
     6781 ctttcaattt cagcagataa ctctgttaat ataccacata ttttttttcc atttaaaata
     6841 acatcatttg gccattttat taatgtattt gctcccatgt tatttaaagc cttcgttaca
     6901 cttgctcctg ctattaaagt tataaatgga gctttgaatg gttccatatc tggttttaat
     6961 ataatactca tccagattcc ttcatgaggt tttgaatccc atcttcttcc caatcgtccc
     7021 ttccccatat cttgatgttc gcttaaaatt acagttccat ctaaactatt tacagctatc
     7081 cttttagcat gttcatttgt tgaatctata gtttcaagat gttcaatatt ttttccaata
     7141 aactctgtat ctaatttata gcaaatattc tgtgggctta ataaatcagt tggattttcc
     7201 gctaatcgat accctttttt atttacagat tctatattat atccctcttc ctttaaggct
     7261 ttcatatgtt tccatatagc tgcacgtgac acccctaatt gttttgataa ttcttctcct
     7321 gaaataaatt cagatttatt atttaacata atctctacta ttttatctcg catatttcac
     7381 ctctaatatg acatgatttc atgacttatt ttcttctaat aaataattat acattattaa
     7441 tatactttta atactattaa ttttaaattt ccttttcatt tattataata gttgttttat
     7501 attttatatt gatgatttat gtgattttat attttattta aataatttta aaataataaa
     7561 aaactgaaag tatcaatcaa attaatacat gcaaatatac tttgcttatt aatttaatat
     7621 tatactttca gttttagtat ttaatccata tcagataata atcttaaaat gaccaaagtc
     7681 ttaaaactat ttatctttat cagatttatc ttctaaattt ttatttatat caataacatt
     7741 gtttctttct tcttcatctt tttctaattt tatagttaat tgctcttcaa cttctttaga
     7801 agaattttcc tctgtaactg cattttcaat ttcattcaga ggtaactctt tattaaatgc
     7861 ttttacaaat tgttctgcat ctagagtttc atatataagt aaagcttgtg ccacatattc
     7921 taatctatcc atattttctt gtaatatact tcttgtctta tcatatgcac catcaactat
     7981 acgttttgtt tcctggtcta tctcaaaagc aacttcttca gaataatttc tcttacttga
     8041 aaaactatta cctaggaata cttcatcatc actgtcaaat gacattggac caagtttaga
     8101 actcattcca tactttgtta ccatacttct tgcagtagct gtaactcttt ctaagtcatt
     8161 tgaagcacct gtagatacat ccttaagtac tagctcttct gctactctac caccaagtaa
     8221 aactacaata ttttctttca tttcattttt tgtagcatag aacttatctt caacaggaag
     8281 ttgcattgta aaccctccag ctcttcctct tggaactatt gtaacttgat gaacaggact
     8341 tacttcttca agtacatggg cacaaactgc atgccctcct tcatggtatg ctgtaagtct
     8401 tctttctttc tcacttatta ctttagattt tttagccaca cctgctataa cctttgttat
     8461 agcttcttct atagtttcca tcttaatttt cttttctctt tttctagcgg ttaatattgc
     8521 agcttcattc attaaattct ctatatcagc aggagtaaat cctggtgttc ttctagccaa
     8581 gacatccatt tttacatcat cacttaatgg cttatttctt gagtgaactt taaatatagc
     8641 ttctctacct tttacatctg gtgtaccaac aacaacttgt ctgtcaaatc ttcctggtct
     8701 aagtaacgct gggtcaagta tatctggtct atttgtagct gccataatta ttataccttg
     8761 atttactcca aatccatcca tttcaactag gagttgatta agagtttgct ctctttcatc
     8821 atgacctcca ccaagacctg cacctctttt tctaccaact gcatcaattt catctatgaa
     8881 tatgatagct ggagcacttt tcttagcctg ttcaaataaa tctcttactc ttgaagcacc
     8941 aaccccaaca aacatctcaa cgaaatcaga accacttata ctgaaaaaag gaactcctgc
     9001 ttctcctgca actgctcttg atagatatgt tttacctgtt ccaggaggcc ctaccataag
     9061 cattcctttt ggtattcttg cacccagttc aatatatttc ttaggattct ttaagaaatc
     9121 tactacctct tgtaaatctt ctttttcctc atctagtcca gctacatctt taaatgtaac
     9181 tctagttttt tcatcatctt tatgaacctt agcttttgat ttaccaaagc tcataacctt
     9241 tccgcctcca ccttgagact gattcataaa cacgaaccaa ataatcacca taaagaatat
     9301 taacagtaat gtaggcaaca tttcgacaaa ccaaggtgta gatggcttag cttcaccacc
     9361 aaaagttagt ttcccagcct tagcttggtc taacacctca tctgcaagtt tatttcccat
     9421 cacttctgtt ggaacatacg acttaaactt tgtatttgta tcttttatag taccttctac
     9481 agaagtttga tttacaaagt ataatcttga tatattctca tctgttaatt ctctatatac
     9541 ttcagagaat tttaaatctt ttattttttc tgtaggctta cctgagaatt gaactatacc
     9601 tactataatt ataaaaacaa gtagataaaa acctgcccct tttagcaact tattcaatat
     9661 agaagccctc ctttcataca ttgctttgcc ctataatttg ttaaaattaa tttttaatac
     9721 ttcttttgtg ttttcatcaa ttttataatt ttcactgatt ttataatctc caacacatat
     9781 tattccttca ctatctgtga ttataggaat tttacatctt tcttctcttg ggatttttaa
     9841 atctatgaat aaatctttca cttttttact tcccatagca agctttatct tatcaccttg
     9901 ccttctactc cttattacta tacccccttt taccttatta aaatcaaacc ctttagatga
     9961 attgtctaat ttcatactct tatacctatc tatactcatt acttgggtct caataatttg
    10021 ttttaattct tttattttaa taaacccatt actaggtata ttgtaataaa attcaatttc
    10081 ctcactaaca atttcctcat tcgttaatat tatactgtct ttttttctat aaacaaatat
    10141 atttcttgga agagttaaca ttttatttac ttttgaatta tcttctaaag acattatatc
    10201 ctctatatgt ctttggtcaa caaaattagt atctcctagt atatgtttta tagaatttct
    10261 aagaacccta actttgatag catcatgtaa gcaaacaaaa tcgtctaaat ttatctctac
    10321 aaagcctttt tcttttatat ttgaaacttc tctaaattta gcttctgcct ctttctcaat
    10381 ataatcgtta tcacttttta aactattgct catcctcact atagattcta ttacatttga
    10441 attaaaatta tccttcatat atggtaaaag gtctaacctt atcttatttc tagtgtatat
    10501 attttctaaa tttgttttat ctatcctcgg atttaaatta taagcttcac aatactcctc
    10561 tatctcactt ctttccacat ctaatattgg tctaattatg caattatctc taatatagtc
    10621 aattcccttt aaacctttta aacctgttcc tctcatgata cgcatcataa cagtttcggc
    10681 ttggtcattg agattatgac ctattgctat tttattagct ttaatcttat ctttgatttc
    10741 ataaaacatt tcatatctta gcttccttgc tccttcttct aatgataatc cctcattttc
    10801 acaatatttt ggtacattaa tagactttac aaagaatata attcccatat cctcacaaag
    10861 tttagataca tataatgcat ctttttgagc ttctatccct cttatttgat ggtttaaatg
    10921 tgctgcatat atttctatat taaaatcttt ttttaatcta tttagtacat gcaataaaca
    10981 aactgaatca ggccctccag aaagacctaa aactatttta tcgccttttt gtattaaatt
    11041 atgtttattt atagtactta gtaccttatc aaatatcata tttatccctc ttacacttag
    11101 ttttattcac ttttaagtat actttctata aaaaaacgct aaacccttgt atcaatttta
    11161 agaaattaaa gtttaatata aatataataa taccaaataa attaaataaa aggtagtttt
    11221 ttcactacct ttataaaatt tctggaaaat agctatagtt attatttagt atctatgtat
    11281 atatctattt tattcctacc taaaaataaa tcttgtacat ttatattata gtctattttc
    11341 aattttatgt gttccccttc ttgtatattt atatccaatt ttcttgtatc aatgtcaatt
    11401 aataaagtac cttgtggggt tacatacttt gtggtactac tctctccaca tttaaacagc
    11461 attgttgagt taatagcacc aaattttttg atactaactt catttttaag tatctttata
    11521 gtattagtta tttctatatt ttcttccttt tccttgtaaa caacatatat tccatcattt
    11581 ttataaaaaa ttttaccaaa ggcagtcatc tctatggtgt ccatatttcc tttttcatca
    11641 tattgtctag tatttatact tatttttaca ctcaacgatt tttcctccat agattcttca
    11701 tataaactag tatttttgta tttctacttt ttgaatccta tcaatttttt tctttaagaa
    11761 ctctcttgct atatctgtaa atttttcagg tatatctgat acataatatt gataagttcc
    11821 atgaatttct gtattgttta taatattttt cacctctaaa acctttttta aatcctttgc
    11881 agtctctttg gctggattaa caagttttat atgctctcca acttcttcgc ctattgttct
    11941 ctttaaaata ggatagtgag tacatcctaa cactaaagaa tctatatttt tttctttcaa
    12001 ttcttgtaaa tatatctttg ctgtcaattt agctacttct gtatttgccc atccttcttc
    12061 gacaataggt acaaataaag ggcatgcttt attaacaatt tctatactct catctatttt
    12121 agatatttcc aaattgtatg cttttgaact tatagttcct tctgttccta ttattcctac
    12181 aattttgttt tttgtagaac ttacagctgt tctagctcct gcttctataa caccaattat
    12241 cggtatatca tacttttctt gagcttcttt taaacttctt gcagtggcag tattacatgc
    12301 tataactata gcttttacac cttttgtttt taaaaagttt atagcttgaa aggtatattt
    12361 aattatagtt tccttagatc ttgaaccata tggtattcta gcagtatctc caaaatatat
    12421 tatatcctca tttggtaata tcttcattat ctcttttaaa actgttaatc cacctaatcc
    12481 cgaatcaaaa actcctattg gtttattgct catctttata caacacctac tttacatttt
    12541 tgtgtttaac aacaacttat ttatcactaa aatatttatt tatattcata attaatatat
    12601 tattacctaa atgattatta tagtttattt tacacaaaaa ataaaggagc tatcttaaat
    12661 tagaaaatat tttctagaaa aagacaactc ctttcactac ttaaaacttt aaatttattt
    12721 tgcaaacaca tgatttccta ttctcatata aggattcaat ctatttatcc atttgcaagt
    12781 ggctatttct ggattccaga aatatactgc tttattagtt gggtcagttc cataaagagc
    12841 ttcttgagct gctttacgtg ctgagtctgt tggtgccatc tttattgaac catcaagcac
    12901 aactgagaaa gcattttttt gatatataac ctcttctatt gtgtctggaa atctagggtc
    12961 caatactcta tttattacta cagctgctac agcaacctgt ccctcatagc tttctcctct
    13021 agcttctcct gcaaccaact tagataataa catcaagtca ttatcagata aatttattac
    13081 ttctttcttt gctatatttt tttcttgttt gtttattttc tcaatctttg ctgttggttc
    13141 atatgcaaat acctctttaa taggcataaa tataaaagtc aaagctaata gtgtagccat
    13201 cagtttactc cacctgtcca tgattaaaac cactccttac attcttattt ttaaaatttt
    13261 ttctctaaat ccttcactac ttcaattact ttaaatttaa tttttactct acttgttttt
    13321 tttggtgtat cttgttttat taacttatat tctttatcag ttagaacttc cttcaactta
    13381 tcatctgtag atttatctat tactccatta gattcatcaa caaagcatag tggagggaac
    13441 ataacacacc accaattttt tccttcacct tttccaatga taatctttaa tgccttatat
    13501 tcaccagctg gaagaactat attagaatat tgtttagtag gaaaattgct atattgtata
    13561 cctaccttta cactgtaatt atatccattt tcaagaataa tatttttact tatttcttcc
    13621 agactactat attccttttt tataatagct tcactttctt ttatactttt tgaattttga
    13681 agctttggtt gtaaatattt tataacttca tctctaacct ttagtttaag ttcttggtct
    13741 tcatctgtat tactatttgc tataacatga aatcttatta atttatcttt gtaatccttt
    13801 gatatattgt ctactttttt tacctcacca tttattacta ttgtcattat tgatatgact
    13861 gatataagac ttaatattaa tagtcccaat ctaatcttaa tttttctcat tgaaaattcc
    13921 ccctttaaga taaatttata tcatcaatta tgtccaatta aatttaattt attcataata
    13981 ttttttaata ctaataaaaa aagctatctt aaaatgatta caatcatttt aaaatagctt
    14041 tttaaacctt atattttata agtctttact aatcatagcc ttatctatca taaactgctc
    14101 tgctttttct atatgctctg tagcatactt cttggatagc tcactatcac ctttaattat
    14161 agcatcaagt aaatatttat gctcttcaac aatattatgt gatgtatcat aagcagacat
    14221 ataggtaact ctaaacctat atacttgttc ccataatgag tttattagtt ggattaattt
    14281 tttattatta gttgctttaa atatacattc atgaaattct acatcaagtt ttaataacgc
    14341 atctacatcg gattccaaag tgcttttttt aaattcttct gatatatctt taagcttttt
    14401 aatatcttct tcactaattc tttcagcggc aagatatgct gctaagcctt ctaggcttgc
    14461 tcttacttct aatacatcca taatatcctt taatgacata tttgccacat acgcaccttt
    14521 tctaggcaac ataacgacta aaccttctaa ttcaagcttt cttattgcct ctctcactgg
    14581 agtcctactt actcccaatt gttctgctag ttgcacttcc attagccttt gaccaggctt
    14641 taattttcct tctaagattg cttctcttaa attctcaaag actacatctc ttaatggctt
    14701 gtaattatcc aagtttagtt tagttaaatt ctccacaaat ttcaacccct ttttgactgc
    14761 tattaacaac atacacctgt ttatattttt ttaataattc tttttttcca attagagcat
    14821 cttctttatt tttaaatagt ccaaaaactg taggaccact tccactcatc atagaaccta
    14881 aagcattatt tttcatcatt atttgtttta tatcacttat ttctttgtgt ttacttatag
    14941 taacattttc aagaatattt accatgcttt ctgatacagc ttttatatct tcagatttta
    15001 aacactctat caaatattta ttatttggtc tttttttaat attattcaaa tctaatcctt
    15061 gataaacttc tttagtagaa acgaataagt ctggtttgca tatcaatata tttgtatcac
    15121 atggtaaacc tttgatgctt gttagctttt ctccaatacc ttgagctagg gcaggtcttc
    15181 ctgatataca aaaaggaaca tctgcgccta aattaagtcc tatttctttt aattcatctt
    15241 cagataatct aagtttccat agttgattta aacctactaa tactgcggct gcattagaac
    15301 ttcctccagc cattcctgca gctacaggaa tatttttttc tatgaatatc tctacaccct
    15361 tttttatata aaatttattt ttaagtattt tggcagcttt ataaacaata ttatcttcat
    15421 ctaaaggaat atctaaacta gtgcttttta cctttatttc atcttcttct aattctttta
    15481 tctttactat atcgtataaa tctatcgttt gcattatcat ttcaacaaaa tgataaccgt
    15541 cttgcctttt tcctaagaca tcaatggata aatttatttt tgctctactc tttagtctta
    15601 taaaatccat tctatcctcc ttgtttaaag aataatgcat cactaacaat aatattatac
    15661 tacaaaaaat aaaataatag ggtattataa taccctatta tacttaatta ctttaaattt
    15721 tttaatatta atctactaat acgacttttt tttctaaaat aagacactta ccaggcttaa
    15781 ttggttcatc aagttttata tcattaagct ctgcaatttc gttttctgtt gtattgtatt
    15841 tttttgctat attccaaaaa gtatctcctt ctttgcatat atatacgatt atgctaggag
    15901 ctttagataa atcatacaca ccttggtctt cacccttgat aataaaattt tctgctttct
    15961 tatctaatgc ttcagtaaat ctcttaattt taataatcaa gtctatctgg tccctattca
    16021 aatcaacttc aactttatca atacatgctg tattaaacac agatgctgta tcagttagat
    16081 tatccatttc tatatcatgt tcaaaaggaa tttcctcact aattttataa accagtttta
    16141 aaccttcaac tggtacaaat aaaatttcaa cttttatgat tccttgtata atgcttttat
    16201 ttccttcaat ataactattt tctatagaca tggttggaca aacgcttaca atatctttta
    16261 tttgtatatc atcattatca tttcttatgc cttctctaac cataaatgtt tcttcactac
    16321 gtcttaaagt cttatttaat tgaataggtt tatggtcaaa ttttattatt ttttgaggcg
    16381 aatatgcatc ttgtaatact tctcttgtaa cttcatctgt aacttttacc ttacaacaag
    16441 ccatacaatc tatttctaaa agacctgtgt tactttcact attttgctta aaaatatgat
    16501 taaaatctga catagacaac aatacttctt cagtcatacc atcactaacc ccaggtactt
    16561 ctacaaattg ggtaaactca atacctactc tatctaactc tacaagttca ccctcgtatg
    16621 tacaagctaa tggatttatt tctaatactc caccaataat aactttattg tcagttactc
    16681 tactttcttt tactttaaca catggattta aacttattat agattgaatt tcctctgtgt
    16741 ttattgttat agtatctctt atagaacttt ctgccttttc tattccaact atatcttgaa
    16801 aacaaatttc ctttctgtgc ttttgtatgc cttctacctg tgccacatct tttacaatgt
    16861 ctagcctttg cttttcaaac aaacttcccc ttatattcat aagagctcct actttaattt
    16921 ttctctcatt cattatagta caatccatat gctctacttc tgaaaataac atgtattcca
    16981 tatcttgaac aacattgtct ttttctatta cttcgtttat atctactttt ccatctacat
    17041 tagaaatagt atttttatca tctgcaatat agattacatt ataattaaaa cttcctctgc
    17101 aaagtatctt cccatctgcc atttcaatct ttttaagtga tatgtatcct tctgttttta
    17161 caatttcata tacatctaat tttttgtctg gtacaactgc ctccgcttcg ataaatgttt
    17221 gaaattttcc aaagtctatt ctattgtcaa ccttaattac atctttaatt aattccatag
    17281 tctacctcct taagtattat aaaaatatca cactatattt atatttaagg agcaaaaaaa
    17341 aaattacacc tatttttaat aggtataatt ttaacttatc tgtaatttat cttgatctct
    17401 aaaaacttgc aactttacat tagatgttaa taaatctgag taactataag ataccctagg
    17461 atatccatta ctttcatcat ctaattttat aacaaacacg cttggataaa ctttttctag
    17521 tataccctct tttgtaataa tctgctttct tcctttatta gctttcaaca atattttctt
    17581 tcctatatgt ctctctaagc ttactcttat cttatctaga gtttgaacag tagccacaat
    17641 atcaccttct ttaacgttta tatgtttaca taatatcaca tataaacatt tttgtcaaat
    17701 gtttaaacta attattttat atattttttg caaaaatgtc aatactattt ttaaagatat
    17761 acagtataat tatgctaatt tttgctaatg taatattgtt tttggcattg cccatctaaa
    17821 ttttcctctt gtttcagaac caccaatccc cttaactcct gtaatagtct gctctataac
    17881 ctcatcaata ggcactacta catcaattct tgaacaagca attttctcca ctataaaaac
    17941 agggtctaat gcatgtatca ttattcttcc aggcgaactt gcatagtttg ctcctgcact
    18001 tattattttt tcataatttg attggcatgc tcctgcaaat atgacaagat tatccaaatt
    18061 tggttgccat ttgcgtgctt cttttactgt tttaacaaaa tttgaagagt ttctatagtt
    18121 actcatatct tctatatctc ctctttttat tgtcattgca tcatgacctg ttattactag
    18181 tatatccgga ttatattttt ctagtagtgc tcttacttct ttatactgat tttgttctga
    18241 aacagctaca cctactgcag gtattccaag ttgagcatat acatccaagc aaatctttaa
    18301 atattcttta tctccatcta tctgtaatac ctttccaggc attccatatg tgttaggatt
    18361 taattgaagt tttggaactg ctcttgtcat tcttttttgt ctttccttag cctttcttac
    18421 tgacttatat aataaatttt ctacattttt atctattaat atatctttta tatcaggtgc
    18481 ttttactaat tctaggtcat caatataagc atctgctatt actctaaatg caattccctt
    18541 tagtatagct attttctcat tattttcatc tacaccaaaa gagactattt taaatactat
    18601 gtctttgtta tgtgactttc tagctacaat gtctcctacc ttcatagtta aacctccaat
    18661 aaatttttat cttagtttat actatgttcg atataaaact ttgtttccta atgtcaaaaa
    18721 aacatttctt ataatacttc ttttattact cttaaagcat ttttatagta tatcttttct
    18781 atctcatctt cactaaaccc ttcttttttt agaggttcat acaatttacc catctgagat
    18841 atatcttcaa tctcaacttt tgaatctatt ccatcaaaat ctgaacctag agatacaaca
    18901 tctattcctc caacatttac aatatgcttt atgtgtctaa ccatatcttc aagtttactt
    18961 tcgcttttat cacttaaaaa taagtggaag aagtttatac ctgtaactcc acctttattt
    19021 gctaatacct taatcatatc atcagttaaa tttctagaat gattcatcat tgctcttgaa
    19081 ttagaatgtg tagcaattat tggtttagaa gaaatcttcg caatttcata aaatccacca
    19141 tctgaaatat gagaaacatc aactaacatt cccaattcat tcatcttatg tactacttct
    19201 ctaccaaaat cagtaagccc tttttctcta tattctaatt tattatgagg aaaactcaat
    19261 tcattcacat gattccaact tattgtcatc attctaactc ctaagtcgta aaatttattt
    19321 aagttttcta atttaccttc aagcactgca ccttcctcaa tagataaaag agctgtaagt
    19381 ttaccttctg attggttttt cataatttct tcatagttag tagctaaagc tatttcatca
    19441 ctattttttt tcatttcctc atgaaattta gttgccatac tcatgcaata atcaaaagga
    19501 tgttttactt cttcagtatc aacaaaaaga gcaaatgttt gagctaatga atcccccttt
    19561 tttaatctgt ctatatcaac agaatattta ttagacttaa gctcacttgt ttctacattt
    19621 tccattaatt ttgctatagt atcacaatgt aaatcaataa atttcatatt tataccccct
    19681 gtatatttta tatttatatc taaaaataga aatagttgtc cttatagaca actattgaca
    19741 actatttttt aatattcttt ttgatattac ttaatcctat tcttctttta agttaggtat
    19801 tactttttta acttcttcaa tttgatgcca tgttttatct atattatttt cactaatata
    19861 tttttttaaa tcagttaaag atttaaaatc tttaactgat aaattgtcat catcatctgc
    19921 aaatcttaaa ataaacatga gactacctta ctttccacaa catttcttat attttttccc
    19981 acttccacat gggcatgaat catttcttcc tatttttgct tctttaacta ttgttttaga
    20041 cttcttataa gcctttatta tttcttttct ttggtctgct ggtagtatat cttcccaacc
    20101 ttgtaaatta tatagccaat gggcttcaac agttaccata ttgttatata atttttccca
    20161 atctattttt atagaaactt ctttatcagc ttctacatct tctaaaacta tatcttcttt
    20221 taaactttca cttattccat ctatgaatcc catgaaaaat tcattagtag ttccaaattt
    20281 ttcggctaat tcgcttactt taccttcaac aacatccatt ttattattta atatttcatt
    20341 gtatattcca gcttcaactt tcaaatattc ttcccagaat tttacttctg cttcttgatt
    20401 ttcatgatta tcacttaaat ttctccattc agtatataaa ctcatacttt ttcctcctaa
    20461 gtatacctat atttttatag tttttatagt ataaaatctt ttagttagat tggaagtttc
    20521 ttctttttga ttataccata ttctatttaa agttaactct tatattatat cataattaaa
    20581 caattctttt aatactttta tagcatactc ttggtctata aaataagggc ttgtcgcaat
    20641 tgttattact tttgcttttt taattaaatt ttttatcttg taaaatttga gttcaaatgg
    20701 tatatagtcc atatcacttg aaaatatatc caaatctata tcaagaacaa actctgattc
    20761 tacatctaaa ccaaatccat ataggctatc tattattatt aattctgaaa atatgttata
    20821 ttttaaggca ggttttataa aacttcccac atttaaaact tcatttgtat acctaaatac
    20881 atcttttatg ttatttatat ctacattata gttttcaggt tctctagtat ccttatgttg
    20941 gtctacatgc actaacttac atccttttgt aaactcaccc tttaacaaag attttatcca
    21001 aaaataaaat gcatggttat gattatcaaa tacatatatc tttttatttc ccaggacata
    21061 ttcgaccata ttctccaatc cttttgcttt tatttcctta ttttcatcta cttcattaaa
    21121 gactacctca ttgcccaatc ttacattatt taatgtacca tttataagtt ttggaacata
    21181 tatactctta ttttctcttt tatcatacga aaatacgtta tttcccaccg gtttttctat
    21241 ataaaatcca ctatattcat aattttccat aaaactttac ttcctccatt gttataatat
    21301 ataatctata attttaaaaa ttaaaatgca cttattgtaa atcatattat ctactataga
    21361 aaacatctta tataactaaa tataatatct tctctcaata tgtattatac aataagtgca
    21421 aaatatatct atataaaata tactacattc ctataacaaa accatcagct tcaattggaa
    21481 ggtaactaac tcttctattc aactccactt ttccaaaaaa tactacccaa tatggtctaa
    21541 aaatactttc aattttgact atttcaatct ctgggattcc acccataaac ctatgagtta
    21601 gtctcatagc tattttattt gcctttgctt ttactcttcg ttcatcctta tcactatatt
    21661 gcacaatatt acaatccaca ttttttataa tttcatatgt aggaaaatct tgtactatac
    21721 taccagaacc tgtagagcca ttaactaaaa ttttcaattc attcacacca ttagaatatc
    21781 tcctactctt gaaaatggat ttagttttgt gaattttaag tgtgacaatt ttaaactcta
    21841 tataatgaag tctaacttca tgagcatatt tattctttaa tattagctta ctaaataaag
    21901 aattttttcc acttttagct atatctatag cttcttcttt tgtaattttt gtaggtaatg
    21961 cccttatatc cataaaatca ttctctttct tatttttttc ttgtcatttt tgaaactcta
    22021 tatatataat caaaaaatat tataattaca actgccataa ctccatatgg aattattctt
    22081 ccaactataa tatcatttct agtcaatata ccataaaata taaatcctgt tattaaaaag
    22141 tacaataata ctagaaaacc atctattcca agccatttta tttctaaatc ttttttcacc
    22201 ttagatacta atttagacat agcagtttct ccttttatag attattttgt gtatttaaat
    22261 tttcccctat tctattgcca atcatccatg caataaatga aaaaggtata gctatcacaa
    22321 gaggttctaa ctcaaaactc tgaactggga atattttaaa ataaccaaaa gtcactccac
    22381 ctacaatcat tcctaaaata ccacccatag atgtccttct tccatttcca agaagtccac
    22441 ctactatagg tacaaatgct gaacccatcc aaatacttcc tacaaatata catgcatcat
    22501 atacattttc aaatctaaat gctacactaa gacccataac tgctgctaag catacaccta
    22561 ttctagtaaa ctttactaat tgtttctgag ataactcttt ttttgtaatt cttccatata
    22621 tatcatttgc taatgtagct ccagctgcta gataatagct atctaatgtt gatattatag
    22681 aacctaaaat tcctattata aatattactc ttattccttg tggtaatgta tctagaacta
    22741 aagttatgta tccagcggct ggagccattt ctggataagt agctcttact ataagtcctg
    22801 tcatagttaa caccatgtca aaacatatcc atagtgaaaa acaagttaat aaagctcttc
    22861 ttccaacctt aggagaatct gctgctgaaa atctttgata aaaagttggg tctgaataag
    22921 ctccaaaaga atatacaatt aacatcaatg ctttcatagc tgacatacct tttgtagggt
    22981 gcataagctg tggtgcatct ttgagtgctt ctgtgagacc ttgaaatcct cctatttgtt
    23041 caaattggcc tggcataacc atagttaaac caaataccat acagaaaaac aataccatat
    23101 ctgtaatggc aactcccata agtccaccaa gtactgtgag tacaacaact attcctacca
    23161 ttattaagcc tattaattct ttatctattc tccatgctac gttgcctata gttcccatag
    23221 cagttatttc tccaagttgt gcacaatata taaacatcaa aattgcccca attatagcaa
    23281 catgcttgcc ataaaaactt tccagtaaat caggaactgt tatattggtt cttatatgaa
    23341 tccttggacc aacccacaat gctaaaggca ttctcccaat atgtgcagct attgaccaaa
    23401 ctgcccatgc agatattcca tatatagctg catactctac actacctact gtaccaactc
    23461 ctccatacca tgatgcaacc aaagttccta ctatcaagga ccatggtaaa cttcgatttc
    23521 ctaggtaata actttccata tcttttacat ttctagaaaa ataataacct attcccaata
    23581 atataaatgc aaatataact ataatcccat tctcccaaaa tgttaacata tctaatctcc
    23641 acattcttat attttaattt ttaactttaa tatctaaata tgaacaactc tacccatttc
    23701 cataaaaata ggtagagtta tataataatt ataagtattt aaacaatctt gttattaagc
    23761 aattttattg ttcaagctct tattttctct tttatttatc ttatttaaag cataagtagc
    23821 aaatatacct ataactgcac atactacaga taaaataaat atatatgtat atcctgtttg
    23881 tccatattta tctaaccaat tacctgcaat agtgtaataa aatgcatctg gagaaaaccc
    23941 tataaatgaa gcaaatccaa ctactgctcc tgtagtttct aaagatatat tagactctga
    24001 aacagatgca aagtatatac ctctaaatcc aaataaaatt acacttagta ttatcatgtt
    24061 tattacagct atccatataa atcctgtact cttaggaata accaagtaag cagctgtact
    24121 tactgtcatt agtataaatc ctacaaacat tactcttata gatgacccaa ctttatctgt
    24181 tattacacca gcaactggag atgctcccat ttttataaca taagttctaa ttattgatag
    24241 agcagaaact agagtcattg gcattacata aacttctgat aggtatggac ttaaataagt
    24301 taaacttgag aatactaaat aagttgaaaa tattataaga ccaattagcc aagcctttgg
    24361 cattgtaact acctttagca atgacttaat gcttaatcct tcatctgatg ctccactatc
    24421 ttttttctct tctactaaga aaaatagaag taaaccacat attatagatg ctgcagaata
    24481 taaccatact acatatttga atcctactgt tatttcagca aatttaccaa agaaataaag
    24541 acctataaaa gaaattaatg tacctgatac acctgataat ccttcataaa aaccaaatat
    24601 tcttccttgc tctgactcac ttccttgcat tctaacaacc ttaacagatg ctgagaaaaa
    24661 agttaatatg gttgtaaatc cccataatac aaatattaaa agtatcatac tatatgatgg
    24721 gaatgtagaa aaataaaacc caagcgctcc tgaagcaatt aaagaaaaag ttatcagctt
    24781 tctaactgag aatctatctg caaaccatcc tcctataaaa taagatacca ttcctactaa
    24841 tccatataaa cttaataagt tccctatttg tgtatgactc aacgataaag cttgttgcat
    24901 tgggtcataa aatgatgatt tcatatatgg taaactatac atagctgttg ttccaaatgc
    24961 caatatgaat attatcaaaa atcttttaac attacttttg ttttccattg atactctctc
    25021 cttaaaattg tattgtttat aatctcattc atgtaatttt attttaattt ttctattgct
    25081 tgtttaaagt catttattat atcatttgaa gattccaacc ctacagctat tcttattaga
    25141 ttttctccat tcatttgaac caatgtatgc tcttccccta agcttgttgc tattgtcgca
    25201 agctctaaag agttcattaa tcttctacta gcttggtctc ttgttaatcc attgatacca
    25261 tccttaagct taaatgaaac tacacctcca cctaaaccat tcatttgagt tttacaaagc
    25321 tcgtattgag gatgagattt taatgctgga tattttacta attccacctt ctcttcttcc
    25381 tctaaaaact ctgctactgc taatccattt tcacaatgct ttttcatcct catatctaac
    25441 gttttcatac ctcttaaaat catccatgca ctcattggtg gtaaagacgc tcctgtaaaa
    25501 caacataaac ttggccatct aactaaatct attaattctt ttgaacctgc tactgctccc
    25561 cctaaagtat ccccatgtcc atttataaat ttagtaagac tatgtattac taaatctgct
    25621 cctaaatcta ttggtctttg cacaattggt gtaccaaaag tactatcaac tatggctaag
    25681 cttttatttt catgagcaat ttctgctatt gtttttatat ctactaaatc taatgatgga
    25741 tttaaaggac tttctatata aactatctta gtatttggtt tcattgcatc ttttacattt
    25801 tgtggattta ctgcatctac aaatgtaact tcaactccaa atttagataa caactcagac
    25861 ataaataatt tagtgtgtga gaatattcca tctgaactaa ctatatggtc accacttttt
    25921 actaatgcta atatagtaga tgttattgcc cccatacctg acgtactaga tatagcactt
    25981 tctgcatttt caagcatagc caacttagct tctaactccg taagagtagg attacactct
    26041 cttgtataca catatcccca tgtcatacac aactcttcaa aatgctctac tgtctttgca
    26101 gcaaatgttg ctgtttgaca tattggtgta gccaatgcac ctgttgttgg gtctgcacta
    26161 tgtccccaat gtattatttt tgtctctaaa tcttgattaa tattgttact cattttgatt
    26221 tcctcccatt ttgacttatt tatacaacgt tttccctacc aaatttcatc aatttagttt
    26281 agtcttaata cattttttca agtatacttt tatatttgtt ataatttcta aaaatatgac
    26341 acttattttg tctttttaca gttctaatta taaactctat agtaactata gagtcaatat
    26401 gtttttgata ttttttttac aatgtttaaa atagttggta caaaaatagg tatatcttag
    26461 aataattaaa gtcatcctaa gatataccta ttttcatacc ataatttaaa caattatata
    26521 aagcattaat ttttttacca taaataagtt tttcaagagt tatcatcttt taataaatat
    26581 attttagtta aatattttaa tattatttaa tctctccaac aaaatacact ctaaaaacaa
    26641 aattatataa ttaaaaaaat atcctataaa aagctaaaaa gtttttctat ttactacaac
    26701 taaaaataag atttgttaga ggtataaatg tatttagttt atttacacct ctagtatttt
    26761 acaaattata cctctactga attgattttt tagcacgaat aagtgtgctc tttgagatac
    26821 cagtcatctt cacaacttct ctatatggtt tagaatttaa taatcctaat gcatattgta
    26881 tctgttgatt gctgtatttc tttggcctac catctttaaa gtcctttttc ttcctagcaa
    26941 attcttttcc taattgagta cgttctatta tcatatttct ctcaagttct gcaactgcaa
    27001 gtaacgtagt caaaaagaac ttacccattg aagtattttc taagagacct atgtttaaaa
    27061 tatgcacact tacttcttta gcaaataaac cttctattag ttgtatccct tctgatgtac
    27121 ttctagctaa tctatccaac ttagttgcaa caagtaagtc tccctttttt agagatgata
    27181 taattttttc aaatttaggc ctatttgtag tagtgcctgt ataagtttcc tttattattt
    27241 tagcatcatt atatttattc aaaatttctt gctgttgctg atacaaactg ttgttgtctg
    27301 tttgattttt tgtacttaca cggcaatatc catatataat aatcatcact tcctaacata
    27361 aaaattttgt acagaagtta cccagaagct tgtttttgct tatctttatc cattttacta
    27421 aaacggtttt ttagtgtcaa tactgttaac ttttgacacc ataataattc ctttataatt
    27481 tgtttgacta tgtcaaaaat taccaatata atgaaattaa tgagtttata caaattggag
    27541 gaaataatat gaatagtctg ttaaaagaag cgatagatga attaaaaaac atccattgcg
    27601 gagaagtttt tttattaaaa gaattgttca aaggctatga atggaacagg ttggagatga
    27661 acataaggtt gaaattagga aaactttttt tgtatgaagt ggtaactaat cccaatttaa
    27721 atgtagaggt catcaataaa aactctgctt atcagcaaat gtataaaaaa aaatagtgac
    27781 ttaaatttat ataatagtat aatcttctta ttgattcaaa agttaaaact tttaatacaa
    27841 aacaatcatt ctattttagt atttatcaat atgtctaaat ttatataatt aacacataaa
    27901 aatagtactt gtttaaatca cattctttaa gatagataaa tcttaaccct actccagcat
    27961 aaatactaaa atagggctta gaattatcta tatttttatc ccataaaata cttaactctt
    28021 cctcttgatt gaacatatat atctggggaa atacaataaa aacgtgaatt tataaaattt
    28081 ccaaagtcag aaaacttcaa cttaaactta ggtataccaa aactttcagg tgctatttca
    28141 tcaaccccaa aataaattac aattccacta tctgtaagat aaaaagcttg gtcttcaggt
    28201 ataactaatt caacattaga ataatacatt tctctatttt catttatttg agatttaatg
    28261 tagtcagtaa ttatattaat ataatcaact ccatctctaa aaatatcgtt aagtaaaagt
    28321 tcttttccag ttgtcaaatc tatattgtaa ttattcaatg tattgtattt aggcccaaag
    28381 ttattggcaa atcccataag gcttaatatc atactcagta cataattttt attaaaagta
    28441 actgcataac ttgtagatac ccagtaactt tgttttggaa gtgaattttg agaagctgcg
    28501 ttattatatt cttgttcttc ttcctgcaag ccatttttaa aattatttac agtcattctt
    28561 acagcattgt ttatgttatt taaaataact gggtttacat acgtagattg atttctaata
    28621 ttgtatataa caggatactt tacatcatat gaaaaatact tacttctttc aaaatcttca
    28681 ttaaattgta catataatat attatatgta caggtatttg tagattgata attttccatt
    28741 aaaatcctcc ccttttataa aaaaatcaga tacaatataa tatgcttaaa acagtaataa
    28801 tgttaatagt aaatgtaaag aatagaaagt atctaaaaca gcaaaaaatg actaattttg
    28861 tggtataata cataggattg agagttattt tataggagga aaaatatgtt attattagca
    28921 gataaatgga aagattatga acttatagat atgggaaatg gagaaaaatt agaacgttgg
    28981 ggcaattatg tacttagaag accagaccca caggttgtat ggccaatgga atctgaatgg
    29041 gctttatgga aaaaccctca tgggcactat cacagaagca ataaaggtgg aggtcaatgg
    29101 gaacacaaaa aaagatatcc agaacaatgg actataaatt ataaaaactt aaagtttcac
    29161 attaaaccaa ctggatttaa acatactgga ttattcccag agcaggcagc taactgggat
    29221 tggatgatag aaaaaataaa gaaagctaac agacctataa aagtgttgaa tctttttgct
    29281 tatacaggtg gagctactgt agcatgtgca tctgctggtg cagaagtatg tcatgttgat
    29341 gcggcaaagg gtatggttaa ttgggcaaaa gaaaacatag aattatcagg tcttaaaaat
    29401 caaacagtaa gatttatagt ggatgatgtt gtaaagtttg ttgaaagaga aataagaaga
    29461 ggtaaaaaat atgatgcaat aataatggac cctccttctt atggaagagg tcctaaggga
    29521 gaagtgtggc aaatagaaga aaagttatat agttttgtag atttatgtat gggagtttta
    29581 tcagataacc ctttattttt cttgattaat tcttatacaa caggattttc tccaatagtt
    29641 cttgaaaatg tattgtctac aacaataggt aaaaagacaa atacaggata tatatatggt
    29701 ggggaattag gaataccagc ttccagagat ggtaagatac ttccttgtgg tatatttgga
    29761 agatgggaga aaaaataatg ataaaggtca tatatgaaga taaccattta ttagttgtag
    29821 aaaaaccagt taacatatta tctcaaggag ataatactaa tgataaagat atggtaaatc
    29881 ttttaaaaga ctatataaaa aaaaagtata acaaacctgg aaatgtgtat attggtttaa
    29941 tacataggtt agatagacca gtgggtggag ttatggtttt tgcgaaaaca tcaaaggcag
    30001 catctagatt gtctgagcag gtaagaagta agactttcaa aaaaacttat ctagctgttg
    30061 ttcatggcaa gataaaatct aactcagata tactaaagga ttttttatat aaaaataaaa
    30121 aaactaatat ggtaactgta gtgaaaaaaa accataagga tgccaaagaa gctgaactta
    30181 actataatgt cttaaacttt aaagaaaatt taagcttagt tcaagttaat ttaaagactg
    30241 gtcgctctca tcagataaga gttcaatttg caagcagaaa acatccattg tatggagacc
    30301 aaagatacgg caaggaaata aataagattg gacagcaaat atctctttgg tccaataaga
    30361 tagaaatcta tcatcctact acaaaagaaa aaatggaatt tacatgtcat ccccctgaca
    30421 aatatccatg gaatatattt taagtctcaa atgaggtgat tatatgagca aaaaattttc
    30481 aataggagaa atgtccaagc ttcataaaat aagcatacag acactaagat actatgacca
    30541 aataggttta tttaaacctg ttcatgttga ccaagaaagc aattatagat attactcaat
    30601 tgaccaattt tcacaattag atattataaa atatttaaaa tatttaggta tgcctttaaa
    30661 agaaattaaa tcaaagcttg atgaaaataa tgaagaaatt ttaaagctac taacaaataa
    30721 aattaatata gtggatgaaa aaattaaaga attagaactt ataaaaaaag tactaagcgc
    30781 aaagaaagag accatggaaa aaggtatgaa agtagatgaa gttggtaaaa tagtgagaaa
    30841 acatattcca cgaagaagta tcttatctat agagtatgaa gaaggattaa gtagtgaaga
    30901 aactatggaa ctttcaagaa gacaaatagc aaatatatta gaagataata tatctgtatt
    30961 ctatggtggc gtaagtggac ttgtatctat agataaattt ttaaaggaag ataaagttat
    31021 ttatgacaat agttttgtta ctgttgaaag agatttattt gatataaaat cacaaaaata
    31081 tataacggaa atttcagctg gtgattttat ttgtatgaca tataaaggac cttacaaaga
    31141 aaattatacc gcttttaaga agctagttga ttatgttgaa tataaaagaa tacctattga
    31201 aaattatata tatgaaatac ctataataga ccctctgtct acaaacaatg aagaagaact
    31261 tctaacagaa attcaaatac aagttaaaaa gagagaaatt gacttaagat gtctagtgta
    31321 gtaacctagt ttacttacaa atcttaatat aattgtctat tatcaacata cgattttttt
    31381 agataatgat tcctaacagt gagattttca aaaaataggc gggagcatgg ctaatgtcaa
    31441 ttcccaccta tttttaatta agccatgtca tcacgaagtg catcaataat attttctttt
    31501 tttatcttat taatagtata caacattgta ataaatacga taaatagaac actaaatata
    31561 cttattccaa tactaaccca tggaatcaca aaatcgatat catctgtaac cattacttta
    31621 tgaattagcc atgaagaaat tactgctata ggaagaccaa agaacaacgc cctcatacca
    31681 taaaaagcac actcaaaatt catcatcttt tggaaatcat gctcagacat tcctacagag
    31741 cgaagcatgg caagttctct acgacgtaac ttaatattag ttgaaattgt attaaacaca
    31801 tttgcaatcg aaatcagaga aatcataatt atgaaagtat acgcaaaaac attggcaata
    31861 aaaatgtaat tacggttctc atccatcatt ccatacatat tgtacagatt gtactcattc
    31921 gtaactccct cactctcaat aatttgctcc atttctgaaa ctgactgagt tggatttttt
    31981 gattgaaagc ttaaactttc aattcctgta gaaacaccag gaatctcaaa cttatcttta
    32041 gctgaataag gagccaatac tctgaagctt gctttcttca tatctgagtt tctgattcct
    32101 ggaggagaat caggtggcac cactttgaca aatgaaatat ttacattttg tctctcaggc
    32161 gtgtccaact tgccattaac ttcaggagtg aggctaacat ccatagaaga attggtaaaa
    32221 atatcaataa tatgattatc tttcgttaac atagaaacgg caatcatttt tgcattttgc
    32281 ccagtatatt cttctgttgg caatccaaga cttttgataa tattcagata agttctatca
    32341 tcaagaaact gcatatctac tggcaattca agcatttcac tcatagaatg taaaccatta
    32401 tagttcaaat aatcgtcagt aagctcactt actttggcaa cacatgaata ggtcatcagt
    32461 ttctgataca aaccttcgta aacaccactt gcagttttta gcttatcata aagcttcaac
    32521 atttcgctgt ctttcatgcc ttgtgtagaa aaaataatgt cttggtcagt aacctctgac
    32581 ctctgatttg acatctgttt taggtctttt actaaagcac ttgtagagat gaatagaact
    32641 atgcttaaaa caagcgacaa tacaatactt cgataacgtt tcttgtttct tttaaagttt
    32701 ttcatagcaa gaactccctc aagaccataa atttgctgtg ttagctttga tgtcttcaca
    32761 gatttagatt caatttttac ctcatttgtc tgacgaatac actccatcac tggtgtgttg
    32821 gcagcctttc ttgctggtat gtaagcagaa attaagattg taaccatgct taccactgct
    32881 gcaacgacga ttgcaggtat agataatgtc agtgttaatg gaacattgac gtagagaata
    32941 tttgcaaagt ttttagctat tacagaaatc acaagtccaa tactgactat accgattaca
    33001 acaccaattg gtataccaat cacaccaata caaattccct caaataacac tgaatttcgt
    33061 aactgttttg ctgtagctcc aacagatgaa agtattccaa attgatgtgt tcgctcgttc
    33121 aatgacatat taaatgaatt atatattaga aaaattgagc ctagcataat tatggcaagc
    33181 acaacgccac caaccgagta taaaaacata ttgaacaaat tattatcaga aatacccatg
    33241 aaacgcaaca cattatcatt gaaaatataa tcatgctctc tagcactact tgtataagag
    33301 cgaacatgac gtggattttt caatgtgaca aaaaggctaa gactgtcagc ctttacttgt
    33361 tcatcttctt tggttatcaa ggtatatcct ggtgcagaag attcttcaaa tacaggcttt
    33421 ctacagatac ccacaactgt ataagttctc ttattttgtg gaataaaagc ttcactccca
    33481 gcagtgtatg ggtcactctg accaagattt tcattttcac tcattcgttt ccctacatcc
    33541 aaagaaatag tatcacctac tgcaaatttg acaccaccat ctgtcgcaac ttttcctgaa
    33601 acaagaatct ctctactatt ttcaggtaat cttccagaaa ttaaagttat aggcaaagta
    33661 tcaaaagctt ctttgctgaa tccagcaata aaaagatatg gtttatctgg atttctgcta
    33721 ccctcaagtg ttgcatatcc aatattttca aatgttacag tattttcaac ttcatcattg
    33781 accctctgtt cctgtacaaa agaagaatca acatccaaaa actcgacatg ccaatcacca
    33841 tattttataa tggcaccatt tatcatatag ttcatcaaag aaactccaaa ggtagtgact
    33901 gctgtaatca tagcagctga caaaacaact cctataattg ttacaaaagt tcgagtgcga
    33961 ttctttttca acccttgcag agcaactttg ttaaaaatat tcattaacgg ttcaccttcc
    34021 tctcatcacg cactactttt ccatctgaaa tacagataat tctatccgcc tgtaaagcaa
    34081 tgttttcatc atgtgtgaca atgatgagag tttggtgata tttactatgg ctttctttaa
    34141 gtaactggat aatttcttgt ccatttttgc tgtctaaact acctgtaggc tcatcagcaa
    34201 gcataactgc tggtgcattc atcaatgcac gaccaatagc aacacgttgc tgttgacccc
    34261 cagaaagctg atttggtaaa tgtgtttttc gttcttttaa accaagtaac tctagcaaat
    34321 catttaacct ttcttggtta accttacgct tatccataag tataggtaag gtgatatttt
    34381 ccactacatt tagtgttggt ataagattgt gaaactgata aatcaatcca acttgtcgcc
    34441 tacgaaaaat agcaagtttt tcattgctct gaccatatac atcttgaccc tccagatata
    34501 tctttccact tgttggtaca tctactcctg caatagaatg tagtagtgta gatttaccag
    34561 aaccagaaga accaataatt gcagtaaact ctcctttttc aatagtaagt gagacatggt
    34621 caagtgcagt aacctgattt tcattcttac cataaacctt acataagttt tcaatcttta
    34681 aaaatgccat tatataagtc tcctttcata tttcataaat atatcataga actttcaact
    34741 tacatttaag tgacatttaa atgagagatt cgtcactttg gaaaacgaat aacaaatatt
    34801 gcaccacctt gtgggtgatt ttctgcagta attgttcctc cttgcctcat aataatcgtc
    34861 ttacaaagtg ccaatcctat tccataacca gctgtgcttg aatttttccc acgataaaat
    34921 ctgttaaaca gacatggtaa atcttctttt ttaaagcctt ctccattgtc atgaatagta
    34981 agttgagtaa acaaaaagtt gtcctcacaa acaatatcaa ttttcccatt atcccccaca
    35041 ctctccatgc agtttttaaa tatattttga attgcttctg aaagccaatt taaatcgccc
    35101 aaaatcttta ctccttttgg tatattaata tgtagagtga tattgtgtag ttccatagga
    35161 atcaaaagtt gatgaagtgc agaactaatc aaattatcca catcaatttc ttctttttga
    35221 aaaactacaa tacctgcatc taaacgtgat aattttaaaa gtgaagtaat cagccagtcc
    35281 atttgtataa gcaattcttc tgtttctcgt atcaactctt ttctctcatc ttcatcagaa
    35341 gtattctcta acagtgacaa aataagagtt actgatgtaa gaggagtgcg aagctggtgg
    35401 gctatatcgg ctaatgaatc agcaagatgt tctttttctt ttttcagtgc ataattttgt
    35461 tctctaatac gtaacgtcat tttagttatt tcactttgca aaatagaaag ctcaccctca
    35521 tctgattcag taatatacag atggttagca ttatgaagca caagattaat ttgttctgaa
    35581 atctgtgcaa tacttttgta tcgattttta gtaaacacaa aaaatgctgt tccaaaggta
    35641 gtggcagaaa caatagaaat tattccagtc atagtactga ttgcaaatcc cagggctaca
    35701 gtgagaatag taattaataa aaataaaata gcaaatcttc gaaactctct atttcgaaac
    35761 ataacttcct cccaatctat accctgtccc acgaacagtc aaaattattt gcggacttga
    35821 agggtcatct tctatcttct ctcgcaagcg tttgatgtag acagtcaatg tattgtcatt
    35881 aacaaactca cctgctgcat cccacaattc atcaagtaat ctcactcttg taataatact
    35941 tttaggattg ctaataaaca ccaataacaa acggtattct aaagctgaaa gaaaaacctc
    36001 attgccattc tttttcacaa caccggttgc cgtatctaca taaagcccac aaatttcaaa
    36061 agttgaccca aaacgcccac tttttcgtag tgctgttcta attcgcgcaa tcagttcacg
    36121 tggacgaaaa ggtttagtga tatagtcatc tgcacccata ttcagcccag taacaacact
    36181 tgattcatca ccagaagctg taagaaagat aacaggaata tcttgatttt ctttgatttc
    36241 tgtacaaatc gtaaacccat ttccatcagg taaagaaata tcaataagtg ccaaatcaaa
    36301 tttattctta gcaatctcta caagtgcttc acttcttgtg gatacatggg ttactataaa
    36361 tccttctgaa ttaagcaaaa gaataagatt tttggcaatt gctttatcat cctcaactaa
    36421 aaatatccgt ttcatttact ttcatcctcc tttattttat tagttttata tattccagca
    36481 gagtaataat acactactat tttacttatt attacacaat tttcattagt ttcttttgtt
    36541 cttatacaat ctatgcataa tacctccatt gatttattat atttcttata acagaaatac
    36601 acaagatagg ataaaaaaca taatgtaagt gcaactattt tttaattcac taattcacta
    36661 acttataaac acacattcca atgcacgcca cctccctgat gatgtactta tcaatctaca
    36721 tgtttactat ggtactccca tgttagtata cactttataa tcaatacttg aaaaactaag
    36781 ctcaatgttt tattatatac ttatatatac cttatattat aaggtatatg ataaaataaa
    36841 gtaggtgaat ctatggactt gaataaagaa gtacttaaag gtcatattga tactttaata
    36901 ttatcaatac taaataaagg ggattcatat ggttatgaaa tagcaaaaat agttataaat
    36961 gaaacaacct ttgaattaaa ggaaagtact ctctatgtat ctcttaaaag actagaatct
    37021 aagggtctaa taaaatcata ttggggaagt gaccaaggac ttggaagtag aagaaagtat
    37081 tacaatataa cagatgaagg aaaagaaaat ttagaattaa agattcaaga gtggaacttt
    37141 atacaaagcg ttatgaacaa atttctaaag agaggggaat agatttatga aaataataga
    37201 agagtattta gaagcactat ataaaaatga tactagcaaa gaaattcaag atttaaaaga
    37261 agaattaaaa gagcatctaa tagattccac taatgaattt attgagaatg gatatgacat
    37321 aaatgaagca caaaataagg caatagaaag atttgatggc agtaatggag tatcagtaga
    37381 attacgttca atctttaaac aaaaaataga acctaaaaaa gtactattac gaaaattatc
    37441 aaattcaaga attgtatttt taaatttatt tggatggctt cttgcagcta ctgcatatac
    37501 aataaataga ggttttggtc atatagctcc accatggata attatacttt taataatatc
    37561 aatagttata ttaataatct taactattat aattaaggga ttaaaaaagg aaatagaaaa
    37621 tgattacaat atatagttat acagttatat tgtaatatat tatttattct tataaacaca
    37681 tattttgaaa ggagcttttt atatggtcaa aaaaattcta ttagaaaaat ttcttgatac
    37741 ctcaggagtt tcatatatca atgaaaaatt gaatctattt aaggatacta aatggatttc
    37801 atttggcacc tatataatga ccgttgatag tttttgttat agagaggatt caaagcacta
    37861 taatccaata atgtctacct ttgattatga atcagagatt tttatagtta atgccttata
    37921 caaggaaaat atctattcta ttaaaagtaa aaaactctat aggaatgtat ctaaaggaga
    37981 taagataatt gttacaatta aatactctta tgataaatat gaaaatctta tacatgaaga
    38041 aattcatgac tatcatctct atcctctttc tcttgattaa aataaaaggc tatagcctct
    38101 atagctaacg cctttaattt aaactacttt gaatactata taattttcat aaaagactgt
    38161 aaataaattt gtgcaaaata tataaaattt atctacagtc ttttgttata caaaatttat
    38221 aatctcttat agaacaaatt tgccatttct caactttatc acttttactc agctatatta
    38281 taaactttta atttatcttt atttaaatgt ttcttcttaa cttctactaa ggcttttagt
    38341 gtatccaaag atgtcattat ttcagtagaa aattcaatag ctgttcttct cattttaaat
    38401 ccatctcttg tagaatcatt tcctttagtt ggtgtattta ttactatatc aacttgttta
    38461 tttcttatag catctaatat atttggtcta ggctcttcaa ttctatttac tatatcagcc
    38521 tctattccat tttctcttaa gctcttagct gttccttctg tagcaacaaa agtatatcct
    38581 aattctttca tatcttttgc tatttctata aactcatctt tgtcatgatt gtttacagta
    38641 gcaagtacta cgcctctttc atcagacata tgtctacctg ctgccaagaa tcctttatat
    38701 aaggcttctt ctaaattttc tcctacacct agtacttctc ctgtagactt catttcaggt
    38761 cctagactta cttcaacttt agataattta gacattgaga atactggtac ttttactgac
    38821 actaattttg gctctttgta aactcctgta ccatatccta aatcttttaa ttttgctcct
    38881 aacatacact tagttgctaa gtcaactatt ggtactccac ttactttgct tatatatgga
    38941 actgttctac tagctctagg attaacttca attatatata attcattttg aaattctata
    39001 aactgtatat taaccatacc aagcacatta aggtctaaag ctattttttt agtatattct
    39061 actatctttt cttttatttc atcagatata ttttgacttg gatacattgt tgtactatct
    39121 ccagagtgaa ctccagctct ttctaaatgt tccattatac caggtattaa tatatcttcc
    39181 ttatcacata tagcgtctac ttctatttct ctaccagtta gatatttatc tataagtact
    39241 ggattcttat ggtctctatc aaatgcatca tccaaatact gaattagttt ttcttcatta
    39301 taagttattt ccataccttg gccaccaagt acataagatg gtctaactag tactggataa
    39361 cctaattcct ttgcaatttc aacaccttca ttagttgtcc atacaccttt tccttttggt
    39421 ctatttatat ctagtctttc tagtaaatca tcaaacttct ctctatcttc tgctgcatct
    39481 atatcgctaa aatctgttcc cagtataggt atattttttt catgtaagaa cttagccagt
    39541 tttatagctg tctgtccacc aaactgtaat attacacctt ctggtttttc tttttctatt
    39601 atatttaaaa cctcttcttc tgttaatggt tcaaaatata acttatctga tgtatcaaaa
    39661 tctgtactta ctgtttcagg gttattgttt acaattatgg tttctatgtc catttttctt
    39721 aaagatttta cacaatgaac tgaacaataa tcaaattcta taccttgacc tattcttatt
    39781 ggaccagaac ccaatactac cacttttctc ttatcactaa caactacctc atcatattgc
    39841 tcataagttg aataatagta aggtgataaa gcttcaaatt ctcctccaca cgtatcaacc
    39901 attttatata ctggttgtat attatataaa cttctcaatt catataattt ttctggactt
    39961 atcttcatta agtcagatat acctttatcc gaaaatcctt ttttctttaa ttgatgtaaa
    40021 tattctttat ctaagtcttc tatttttaaa acttttaatt tttcttcttg ctctactatc
    40081 catttgaatt tatttataaa ccacttatca acaccagtta tttctgatat catttctact
    40141 ttatagcctc ttcttatcat ttcagctaag tcaaatagtc tctcatcatc aggcactact
    40201 actctagcct ttaattcctc taatgttcta ccttctgatg gtgcatgaac caacgaatat
    40261 tttcctgttt caagtgatct tatcccttta agaatagcag cttcaaagtt actacctata
    40321 ctcataattt caccagtcgc catcatctta gttcctaatt ttctattggc atgtctaaat
    40381 ttatcaaatg gccactttgg tatttttacc actacataat ctaatgttgg ctcaaaacaa
    40441 gcataagttt tcttagttac tgcattttct atctcatcta aagtgtagcc taaagctatc
    40501 ttagctgcta cttttgctat tggatatcct gtagcttttg atgctaaggc tgatgaccta
    40561 cttactcttg ggtttatttc tattatcgca tattctaaac tatgtggatt taaagctatt
    40621 tgaacgttac atccaccttg aacctctatt gcatttatta tgtctattga tgcctttcta
    40681 agtagttgat actcttcatc acttagggtt tgacttggag caacaactat actatctcct
    40741 gtatgaactc cgactgggtc tacattttcc atattacata cagttataca gtttccattt
    40801 ccatctctca ttacttcata ttctatttct ttccaacctt ttatactctt ttcaagaaga
    40861 acttgtccaa cagggcttaa ttgtagtcca tgtgaaagta tttctcttaa ttcttcctca
    40921 ttttcagcta tacctccacc agttccacct agtgtgtatg ctggtcttac aactactgga
    40981 tatcctattt tattggcaaa ctcaagacct gcttctaaat ttgtaactat gtcactaact
    41041 attacaggtt gatttatttc tttcattact tctctaaata aatctctatc ttctcccttt
    41101 tttatagact ctatagatgt ccctataact tttacattat atttatctaa tatcccagca
    41161 tcatgtaatt ctacagctaa atttaatcct gtctgaccac ccatacctgc aagtaaacta
    41221 tctggtcttt ctttttctat tattttttct ataaattcta ttgttaatgg ttctatatat
    41281 attttatctg caatctcttt gtcagtcatt atagtagctg ggttactatt tactaataca
    41341 acttcaattc cctcttcttt taatgcttgg caggcctgtg ttcctgaata gtcaaactct
    41401 gcagcttgac ctattattat tggtcctgac cctaatacta aagttttctt tatattatct
    41461 aatttaggca taactctttc tccttatcta aacaattttt acagctctta tcttcatcat
    41521 ctatacaatc aattttaatt actttatttc atattaagtt caaatttacg tattaataca
    41581 tccatttaat acatctatgt taattaaacc aaactttttg atttaagtta ttcttatctt
    41641 ttagttatct attctaatat tatttatttt actaactcta aaaatttatc aaaaatatag
    41701 tcattatctt ttggtcctgg gcaagcttca ggatggtatt gaacactgta tacatctaac
    41761 ttctcatgtc tcattccttc aacagtatta tcatttaaat ttatatgtgt cactttcatt
    41821 tgttcaggaa cttctgaaac ataataacca tgattttgag aagttataaa tacttttccc
    41881 tcttctaaat ctttaactgg atgatttcca cctctatgtc caaatttaag tttagcagtt
    41941 tttcctccaa gagctaaagc taaaagttgg tgtcctaagc atattccaac tataggtttt
    42001 ttaccaataa gagcctttat attttctata acatcttcta ggtcttctgg gtctccaggt
    42061 ccatttgaca agaatattaa atcagggttt atactcaata catcttctgg agatgttgta
    42121 gctggaaata ctgttatatc acatccacga gctataaacg atcttaatat atttcttttt
    42181 accccaaaat ccataacagc cacttttgga ccatttcctt ttatatgctc tacttctttt
    42241 cttgtaacag ttctaactgc ttctgtattt gaaaacttat ccaatttatg tttaacatct
    42301 tctaatttac tgtcttctaa tgtaattata cctttcattg tcccattatt tctaagtatc
    42361 ttagtcaaag ctcttgtgtc tattccttca agtccaataa ccttattttg ctttaaatat
    42421 tggtctatat caatttcaca tctaaaatta cttggagaat cacttttctc ccttactatg
    42481 aatcccttta cttgaacttt ttcagactct gctgatgata aatttatacc ataatttcct
    42541 acaagaggat aagtcatagt aactatttga ccatagtaag aagggtctgt taaaacttca
    42601 ccatatccta tcattgaagt attaaatact acttctccta tactttcttc taaatatcca
    42661 aatgcctttc ctataaaaac tgttccatct tctaatatta accttgcttt catactacag
    42721 tacctcctat aattctcttt agataaacta aagaacatta actaaatata agcttttaaa
    42781 tatctatatc tatttttcac ttttacattc tagttttata cttatttgca tttatttttt
    42841 atctttttct attatactac aaatttctta aaaaaaagaa gttatctcaa aagtaaaaac
    42901 ccctagaaaa aataacctct ttttttaatt taataattaa attcttaaac tatacaatca
    42961 acttaatttc tattcagcta tattgtaaac ttttaactta tctttattta aatgtttctt
    43021 cttaacttct actaaagctt ttagtgtatc cagagatgtc attatttcag tagaaaactc
    43081 aatagctgtt cttcttatct taaacccatc tcttgtggag tcatttcctt tagttggtgt
    43141 atttattact atatcaactt gtttatttct tatagcatct aatatgtttg gtctagactc
    43201 ttctactcta tttactatat cagcctctat tccattttct cttaagctct tagctgttcc
    43261 ttctgtagca acaaaagtat atcctaattc tttcatatct tttgctattt ctataaactc
    43321 atctttgtca tgattgttta cagtagcaag tactacacct ctttcatcag acatatgtct
    43381 acctgctgcc aagaatcctt tatataaggc ttcttctaaa ttttctccta cacctagtac
    43441 ttctcctgta gacttcattt caggtcctag acttacttca actttagata atttagacat
    43501 tgagaatact ggtactttta ctgacactaa ttttggctct ttgtaaactc ctgtaccata
    43561 tcctaaatct tttaattttg ctcctaacat acacttagtt gctaagtcaa ctattggcac
    43621 tccacttact ttgcttatat atggaactgt tctactagct ctaggattaa cttcaattat
    43681 atataattca ttttgaaatt ctataaactg tatattaacc ataccaagca cattaaggtc
    43741 taaagctatt tttttagtat attctactat tttttctttt atttcatcag atatattttg
    43801 acttggatac attgttgtac tatctccaga gtgaactcca gctctttcta aatgctccat
    43861 tataccaggt attaatatat cttccttatc acatatagcg tctacttcta tttctctacc
    43921 agttagatat ttatctataa gtactggatt cttatggtct ctatcaaatg catcttgtag
    43981 gtattgagat aatttttctt cgttataagt tatttccata ccttgaccac caagtacata
    44041 agatggtcta actaatactg gataacctaa ttccttagca acttcaatac cttcgttaag
    44101 tgaccataca ccttttcctt ttggtctatt tatatctagt ctctctagta aatcatcaaa
    44161 cttctctcta tcctctgctg catctatatc atcaaaatct gttcccagta taggtatatt
    44221 tttttcatgt aagaacttag ccaattttat agctgtctgt ccaccaaact gtagtattac
    44281 accttctggt ttttcttttt ctattatact taaaacttct tcttctgtta atggttcaaa
    44341 atataactta tctgatgtat caaaatctgt acttacagtt tcagggttat tgtttatgat
    44401 tatggtttct atgtccattt ttcttaaaga ttttacacaa tgaactgaac aataatcaaa
    44461 ttctatacct tgacctattc ttattggacc agagcctagt actatcacct ttttcttatc
    44521 actaacaact acctcatcat attgctcata agttgaataa tagtaaggtg atatagcgtc
    44581 tatctcacct gcacatgtat caaccatttt atatgctggc ttgatattgt atagacttct
    44641 caattcatat aatttttctg ggcttatctt cattaagtca gatatacctt tatccgagaa
    44701 tccctttttc tttaattcaa gaagatagtc tttagttaaa tcttcaattt tcataacttt
    44761 taatttttct tcttgctcta ctatccattt gaatttattt ataaaccatt tatctatacc
    44821 tgtaatttgt tctatcattt ctactttata gcctcttctt atcatttcag ctaagtcaaa
    44881 taatctctca tcatcaggca ctacaactct tttctttaat tcctcaatac ttctctcctc
    44941 agatggtgtg tgaaccaatg aatattttcc tgtttcaagt gaccttatcc ctttaagaat
    45001 agcagcctca aagttacttc ctatactcat gatttcacca gttgccatca tcttagtgcc
    45061 taattttcta tttgcttttt taaatttatc aaaaggccat tttggtattt ttgctaccac
    45121 ataatctata gttggttcaa aacaagcata agttttttta gttactgcat tttctatctc
    45181 atctaaagta taacctaaag ctatttttga cgaaacttta gctattggat atcctgtagc
    45241 ttttgatgct aaagctgatg atctacttac tcttggattt atctctataa ctgcatattc
    45301 aaaactatgt gggttaagtg caaattgaac gttacatcca ccttgaactt ctactgcatt
    45361 taatatatct aaagatgctt ttttaagcat tgcacattct ttgttactta aagtttgagt
    45421 tggagcaaca actatactat ctcctgtatg aactccgact gggtctatgt tttccatatt
    45481 acatacaact atacaatttc cctttgaatc tcttattacc tcatattcta tttccttcca
    45541 gccttttata ctcttttcta ttaatacttg tccaacaggg cttaattgta gtccatgtga
    45601 aagtatttct cttaattctt cctcattttc agctatacct ccaccagttc cacctagtgt
    45661 gtatgctggt cttacaacta ctggataacc aattgtaagt gcatagtcaa gacctgcttg
    45721 taaatctgta actatatcac taactattac aggctgattt atttctttca ttacttctct
    45781 aaatatatct ctatcttcac ctttttttat agattctact gaagtaccta ttatttttac
    45841 tccatatttg tctagtatac ctttttcata aagttcaact gctaagttta atcctgtctg
    45901 accacccata cctgcaagta aactatctgg tctttctttt tctattattt tttctataaa
    45961 ttctattgtt aatggttcta tatatatttt atctgcaatc tctttatcag tcattatagt
    46021 agctggatta ctatttatta atacaacttc aattccttcc tctttcaaag attggcaagc
    46081 ttgtgttcct gaatagtcaa actctgcagc ttgacctatt attattggtc ctgaccctaa
    46141 tactaaagtt ttctttatac tatctaattt aggcataaat ttttctcctt atctaaatgg
    46201 tttttactat ctgaaaataa tactaaatct atattaatgc taagaattta ttaaatatac
    46261 aatctaaatc ttcttttgtt gtgtattctg gaatgtactg aacactatat attggtaatt
    46321 ccttatgtct cattccttct atagtattgt catttaaatt tatgtgagtt acctctgtat
    46381 tttctggcat ttctgaaaca ttatatccat ggttttgaga agttataaat acctttccag
    46441 tttctaaaca tttaactggg tgattgcctc ctctatgtcc aaatacaagt tttgaagtct
    46501 ttcctcctaa tgccagtgct aaaatttgat gtcctaaacc tattcctgtc aatggctttt
    46561 tgcctattaa tttttttata ttttcaacta tatcatttat atcctctgga tttcctggtc
    46621 cattagataa taaaattaag tcaggattta tatttaaaat ttcttctgct gtagtcattg
    46681 ctggtactat agttatatca cagttacaag ctttaagaga ctctagtaca ctatttttaa
    46741 caccaaagtc tataactgta accttagcac cagtaccttt tatattttca gtttcttttc
    46801 ttgtaacatt ttttactgaa tctttgttac aatgctcttc taacttagac tgaacatctt
    46861 gtaatgatac attttctaaa gttataattc ctctcttagt tccattgttt ctaataattt
    46921 tagttaatgc tcttgtatct attccttcaa gtcctattac cttattttgc tttagatatg
    46981 tgtctatatc catttcacat ctaaaattat ttgggttatc acttttctct cttacaataa
    47041 gtccttttac ttgcacctta tttgattcaa catcttctaa atttattcca tagtttccta
    47101 taagtggata agtcatagta actatttgtc cataataagt tgcatctgtc aatagttctc
    47161 catatccagc cattgaagta ttaaatacaa cttctccaat agtttccttt agatatccaa
    47221 atgcttttcc ttcaaatact gttccatctt ctaaaattaa tttccccttc atataagcta
    47281 cctcccaaat attttatcta agcattttct atttctctta caatattaat agctgattct
    47341 cttggatctt ttgcttttgt tataggtctt ccaacaacta aataatgagc acctcttttt
    47401 attgcatctg atggagtcac aactcttttt tggtccccaa cctctgctga tttaggtctt
    47461 attcctgggc aaactgttat aaaatcagtt ccacatgctt ctactatttt atctacttct
    47521 tgcgctgaac aaacaacccc atctattcct gattcttttg ccagtttagc tctctttata
    47581 gctagctctt ctgtcgtcat attacatcct atgtcctgta aatcttggtt gcttaatgaa
    47641 gttagaactg ttactccaac tactaatggc ttttctatat ttaatctttc tgcttcttct
    47701 ttagcaacta gtgcacattg tctcattcct tccatgtctg atacatgtat tgtcattaac
    47761 caaacattat ctctgactgc agctctcact gcacttttca tagtatttgg tatatcgtgg
    47821 aatttaaggt ctaaaaatat ttttttgcct ttttctttaa gataatctat cgttttacct
    47881 tttgtggcaa catattgctc taaccctact ttaaatatat ctacactatc ttctaatttg
    47941 tctattagtt ctttagcttt atcaaattcg tcagtatcaa ttgcaactat caacttttct
    48001 ttaccattta tcatttttac atctcctttt taataaagcc taaatcttca taaaaaaatc
    48061 ctcacaccaa aagaggcaca aggattttat ctatacataa ctctattcat tagctatgag
    48121 atatctttcc cagtctctct ggactagttt aaaagacttt attatattta aatttttatt
    48181 ttatactcat caaaaacctc tagaagattt actagaggtt atatgctaac actatctata
    48241 accctttagt ctctctggac tactttaagg aatttagctg taatattttt ctttatttat
    48301 ataattttat gtatctataa gataacttaa agttttatct tttttataat taaaccacta
    48361 attgcttttt atgtcaataa gtctttgaat tattcttcat ctttatcaaa caattttttc
    48421 tcaaaatatg attctgcatt atatattgca gcaactggat tatgcccagt tactctatct
    48481 ttgacaacta aagttgttat aggagcttcc atatatttca tggctaaagt atcatgacca
    48541 acacataatc caagaattac attaaggtca accctagctt catttaaaaa taaagcttgt
    48601 cctattggat tgcacattac ctcatctgaa cattttgata ttgtttgaga tgcttctagt
    48661 ccaattgtac tcttaggtat tgccccattt ttacatataa cagaaaatac ttcaaaccca
    48721 tgatgttcaa atactttttg tactgtttgc atttctcttt ttagcccaat acaaaatgct
    48781 ataccaatct ttttataacc acacttttta gcaaactcta taatctcttt tagtctagta
    48841 tattgacaat acccctctgc ttcaactagt ccagcattat aagctatttt tttattctct
    48901 tcttcttcat aaagttgctt tgctttttgt tgtagctcaa tttctctagt tggacatatc
    48961 ttcattaatt tatccatatt tccattagaa cagcctctaa gattacattt tccacactta
    49021 tacatatcca atatcccctt ccaaaatttt attcatcttg taattcttct ttttctagac
    49081 ttacattttc ttcttggatt tcttcttctg gtttcacatg ctcaactaca gttataaaat
    49141 atgattttcc tattttattc cttataggaa gtttttcata tgaaacatct attttatttt
    49201 ttatacaagc tatatcaaaa tgtcttaagg ctacacctaa gctaacctta ttcatatctt
    49261 cacagtgttt cttaggtttc ttttcaaata aatgaagacc tcgttcatct ttatggaaat
    49321 accaaggttg agaatttttt acagatggag ctcttcttgt caattctaaa atatctttcc
    49381 actttctatt cctatttatc ttatttatca tatcttttac tggctttcta tctggtctag
    49441 catatctagt cctaaacaac tcttcatttt ttgctggata tccaaatgct attattatat
    49501 aaggattttc tattttgttt tcatcttctt cttctgtttt tattccaact aaataatcta
    49561 agtcatcttc ctcatcttct tcaaagctct tattcccaat atctacaaat tccaagatat
    49621 cttctctctt taagtttcct tcaagccaac aggtagctat tcccaatgtt gtaagacgta
    49681 aaactacacc ttctgtagca aaccctatat tctgtaaata gtcctcacct ttatctgatg
    49741 tgactactat ataatgaggt gcctttacct tacattcctt acccatcaaa aaatgtatta
    49801 tatgacctct atcaacaaca tgtgctttaa tatttaaatc ttcatttaag tattctaaat
    49861 ttttacaact tctttttatt tcttccatta atggcttttt tatcttctta ctggaaaaat
    49921 ttcttacaga ttttctataa aaaatggctt cataaagctc catttatgcc ctcctaactg
    49981 aactcttctg acctataaac tctataaatt tatataaata ctttatattt tttatagttt
    50041 tatttccttt ttcctcctgc tctattttga aattcataag aatatctact ctagtttaat
    50101 atagcagtct aaaggcttaa attctatctt gtcaatgtct atatattagc acaatttttt
    50161 tatttgattc tctatgctaa tttaaataac aacactagct attactttta taattaagct
    50221 ttgccagaaa aatttttttt catttataaa tatctatctc attattatat tataagtttt
    50281 tttcggtatt cttgtatagc ttttcactaa aaaagtattt ttatttctac tttaatacta
    50341 ttatcaacaa aaaacatact gcttaaatag gtttgctatc ttcacaatct gttttaatta
    50401 aaatatattt ttttatttct caatctataa agtataaata ttttgaatat gacctaaaat
    50461 ctaagtaaag ttataatatt ttataagttg ttcaatatta aaaacataag taatgttata
    50521 atactttata agttattcaa tattaaaaat ataggaggat aaatatgaat ttaaatagaa
    50581 atttagaaaa atacgctgaa ttagcaataa aagttggagt taacatacag ccaggtcaaa
    50641 ttctacttat aaaatcacca atagaatgtg ctgattttgc aagaaatgca cttaaggaag
    50701 cctataaatg tggtgctaaa aatgtgtata tagagtggtc tgacgaagaa agcactctta
    50761 ttaagtactt atatgctcca gatgaggcat ttcatgagtt cccaaagtgg acagcagaac
    50821 aatatgtaga tatagcaaaa gaaggtggag catttttatc agtctatgcc caaaatccag
    50881 atttattaaa agatgttgac cctgaaagag ttgcaaattt tcaaaaggca tctggaaaag
    50941 ctttaaaaga atggcgttct tacactctaa gtgataaatg taaatggagt atagtctctg
    51001 tgccaacaaa agattgggca aaaaaagtgt ttccaaattt atcagaagat aaggcaatag
    51061 aaaaattgtg ggatgctata tttaaatgtt caagagtaga tggtcaagac cctataaaag
    51121 catgggaaga acataataaa aaccttaaat ctaaaatgga ctttctaaat aaaaataact
    51181 ttaaaacttt aaaatataaa tcctcaaaaa ctgatttgac tttagactta ccagagggtc
    51241 atgtctggct aagtggagca tccaaagacc ctaatggagt aagttttaat ccgaatattc
    51301 caactgaaga gatttttgga atgccacata agtttaaagt aaatggaact gtttatagta
    51361 caaaacctct tgtttatggt ggaaacataa ttgataattt cttcttaaca tttaaagatg
    51421 gaaaaataat agatttttct gctgaaaagg gactagatac actagaaaaa cttattgaaa
    51481 cagatgaagg ttctcattat ttaggagaag ttgctcttgt tccatacaac tcaccaatat
    51541 ccaatacgga tataattttt tataatactc tatatgatga aaatgcatct tgtcactttg
    51601 caattggttc tgcttataaa acttgtctag aaggtggaaa caatttaaaa gatgaagaat
    51661 tagataaata tggtgtaaat gacagtttaa cacatgtaga ttttatgatt ggttctgctg
    51721 atatggatat tattggtgaa acttatgatg gaaagcaaat acagattttt aaaaatggtg
    51781 attgggcttt ttaacatatg attttaacta aaaagggctg ttggaagtta taccagactt
    51841 cccagccctt tttaatgttg atgataaata ttttttatat taattaatct cattattata
    51901 gattaattcc tattgtttta aacataagta tctaaaactt atatttatat tatatataaa
    51961 atatcctatt tagtaaaacc tttattttaa tttacatgct aaaaatttaa ctttgctatt
    52021 tcaacagcag actttgcatc ctttgaataa taatcagcgc ccatttcttc agcgtattct
    52081 tctgttaaaa ctgcaccgcc tacaaatacc tttgcattta tctcattatc tctcagtgcc
    52141 tgaattgtat ctttcatact ttgaacagtt gtagtcataa gtgcacttaa tcctactaat
    52201 tttatatttc tttttttagc aacttccact acttcttcaa tagggacatc tttacctaaa
    52261 tctataacct catatccata attttctagc attattttta ctatattttt cccaatatcg
    52321 tggatgtctc cttttactgt agcaactatt atttttcctt tagatacatt attgctactt
    52381 ttacttaata aagtttcctt tattgtattt aatgaaactt ttaccgtttc tgctgattga
    52441 atcaattgtg gtaaaaatat atctccacta tcatatcttt ttcctacttt atcaagagca
    52501 ggaattaaaa tcttatctaa tatataattt tcatccttct cttttaaaag attcagtgtt
    52561 acattttttg cttcatcttt taatcccctt tcaactaaaa tatccaaggg caaatctttg
    52621 tcaatctttg tagatgaatc caattttttt gaattattta tattactata ttgatttata
    52681 tagtttatac atcctttatc tgtgttattt aatattttaa aagaattgat agcttccatc
    52741 atactacatt catttggatt tataattgct aaatcaagcc ctgctcctaa agctaatgtt
    52801 agaaaagaag cattaagtgc ttttctattc ggaagaccaa atgaaatatt tgaaacacct
    52861 aatatagttt ttactcctaa tgtctttacc attgctatgg cttttatagt ttctattgct
    52921 tcttcttgtt gtgctgaaac agttaatgat aaacagtcta taaatatgtc ttttggtttt
    52981 atgccataag aaactgctct atcaactatc ctttttgcta tttcaaatct ttcttcagcc
    53041 tttttaggta tccccttttc atcaagtgta agtccaacta cacacgaacc atacttttta
    53101 actatcggta atatgctttt taaagactct tctttgccat ttacagagtt tactattgtt
    53161 ctaccattat aatatctaag accttgttct aaagcctcta cattggaaga atcaacttgt
    53221 aaaggtgtat ctactactgc ttgaatctct cttattaatt ttggcattaa ttttttttca
    53281 tcaatctctg gaagaccaac attcactcca agtatttgtg ctccagcatt tacttgttct
    53341 aagcctaaat ttatagcata atcaacattt tcatttttta atgcttcttg tagagctttt
    53401 ctacctgtag gatttaatct ttctccaaca actgtaggtg attctacttc aacaaatttt
    53461 gatggtgaac aaactacaca tttatcaatt ttctcgatac atccctttgt aacagaattt
    53521 atattctcag atatttcttt tataaaactt ggattcgtac cacaacatcc gcctattata
    53581 gtagcaccaa cctcaacgaa ctttttaacc ccttcaaaaa attcttttgc atcaacatca
    53641 tatatagcct ctccatcaac tatatttgga agacctgcat ttgcttgaac cataacaggt
    53701 actgtagctc ttgatgctat tttttcaact attggtaaaa gttgtttagg tcctaatgaa
    53761 caattaactc ctattgcatc tacacctaac ccttctatag tagccaccat acattctggc
    53821 atacatccag taaaacttct tccaccttca tcaaatgtca tagtacagaa aataggtaaa
    53881 tcagaatttt cttttgctgc taatacagct actttagctt catataaatc catcatagtc
    53941 tctattacta tcacatctac tccagattta acgccttgca gtacttgcct tttaaatatt
    54001 tcatatgcct tatcaaaact taaagtaccc ataggctcta gcatctctcc tataggacca
    54061 atatctaaag ctacatatct tggtttagta ttatctacat tttctatagc tttcctagcc
    54121 accaaaacag cattatcaat cacttcttct acagtatact cactatctaa ttttagttca
    54181 ttacatccaa aagtatttgt aagaattaca tttgaacctg cctctaagta tgctgtgtgt
    54241 atttctataa gtttctctgg attttgaata ccaaatactt ctggattttc acctagcttt
    54301 aacccttttt gttgaagcat tgttcccatt gcaccatcga atattaatat attatttttc
    54361 agatattgtc ttatttccac aagagttcgc tccttttcta tatgtacagt ttctatagtt
    54421 tttacaattt tcacacgact tttctttctt agatttattt attcttgtat cagaaatacc
    54481 tataatagcc actaccgact ttcttggtat cataattcca ttagaagtaa ttgttagacc
    54541 tatttgtttt tgagcattta aaacgtttaa tatatctata tttttttcta ttggtaaatc
    54601 tccatatcct ggactatatc gcatagttat aaatttattt tgttttaaaa aaaccttttc
    54661 tacattatct tgaacaatgt cacacacttc ttctattgct gttgttccac atgaatcaat
    54721 tattagtcct tttgttaaat ctgaataaga gtgtcgcctt atttcttttt ctatatctat
    54781 ccctatagta gctgccataa ttacacattc attacattct tttaaaagtt catatacatc
    54841 tttactctct aaagttaaat ttgttccctc taattctaca atattatctt tatttattct
    54901 aataggataa atcctagata aatatctagg atttatttta tttttagtta tagctacaca
    54961 ttcatcaata gtatctttaa ggtctttatc tatctcttga cctctgtatt gtaaatatct
    55021 taaaacttca ctttgattta tgcttatatc ttctcttcca attaaattat tctccatata
    55081 tatttaaaga aaatccttta tctaaaacat cttttgcata ttcctttgct ccaaataaag
    55141 ataagtctct gtagtttcca cattctatag ctgtagctgc tggcatttta tctgattcaa
    55201 gaactttttt taatgcttct tctaaaccaa tcttaactgt tttggcatct acatctcccc
    55261 atagtattaa ataaaatcct gttctacatc ccattggaga taaatctatt acaccatcta
    55321 atgtatctct taaataggta gccaaaagat gctctaaacc gtgcatagca gcagttccaa
    55381 aactttctac atttggctgt aaaaatctca agtcaaattt agttacttta tctcccttta
    55441 ctccatcaag tacactacac tttcttacaa aaggagcttt tacttttgta tggtctagct
    55501 taaaactttc tactttttcc attatttaat cctccattat actttaaaat ttgttacatt
    55561 aattctaaaa aaaactcttc ctatctatta ttgataagaa gagtatatta tttcaagtca
    55621 tctcatcgtt gttagcagga ccacctgata aaaggttggt ataggatcac tgagctaact
    55681 ctctccccta actcttgata agtatcttat taaactgact taaattatat attacttttt
    55741 tatttttgta aacactttat tgttataata tttatatcac gtaatcgtac ttttatttta
    55801 taactaagct gattgtatta ttggcagttg tacctcaaat acagtttgat atttatcact
    55861 tgaaacagta atttctccac catgtaaatt tacaatattt tttgtaattg caagacccaa
    55921 cccagaacct ccaacatttc tatttctcga tttttcaact ctataaaatc tatcaaatat
    55981 atttggtaaa tctaacacag gaattggttc tccataattt atcactttta caaccgctat
    56041 atctcccttt ttctctgtaa ctatatctac ataaagtcca tcttttccat attttacagc
    56101 attagttata aggttttcaa atgctcttac taatttattc ggatcagctt ttacaattaa
    56161 tttttcttca ttaaaattaa ttctactaac cataaattct tgtttaaaat aaatttcaaa
    56221 ttgagatatt acctgactta acaattctac taaatttatt tctattttgt ttaattttat
    56281 tgtattattc tgcattttag tcaattcaaa caaatcattt ataagaacgt tcaaattttt
    56341 cgatttttca tatgcaatat caacataata catcatctga acttcatctt tatacttacc
    56401 ttcttctata actcctaaat aacccattat ggatgtcaaa ggtgtcctta agtcatgtga
    56461 cacatttgtt attaaatctg tttttgtctg ctgagcttgt ctctcttcaa tagttatatt
    56521 tctaagttga tgaacgatat tattgatttt atatgctagt tcatcgatat catccttttc
    56581 gttatctttt aatatatcta agtcatattc aatatctata cttttttcta aattaccttc
    56641 atccattaaa tttacagcac tcttaatgat ttctaatttt tgattttttc tattagtctt
    56701 tcttataaaa tctacaattt gcttatttct cttgtacgat attatggaat aaattgctaa
    56761 tgatgtgatt gtaaataaaa atggataaaa taaactctct cctataagac ttctgaaatc
    56821 tcttaactga tatacaagtt gattaattac agatatcgca ccattgaaat ataatgattt
    56881 tattatatac atacttgtta caataagcat tgaagttaaa gcacagctta ttataagatc
    56941 taatataggt cgaaacatat gatttaataa gcttttattt ttcaatttta tatcctactc
    57001 cccatacagt atgaattatt ttttctccat ctgtatattt ttcaatttta tcccttattc
    57061 tgctcatatg aaccattaca gtattattag attggtaata tttctctttc cacacttttt
    57121 caaatatttc ttctgtacta tatactctac ctttattgtt tgctagtaaa tataatatat
    57181 caaattctct tgatgtcagg attatgtcat ttccagctac tgttacacta tgtttttcct
    57241 tatctataat tactgctcca acttctatga catctttatc ttcattatta gcaccactaa
    57301 aatagtatgc tcttctaatc agtgacttca ctctcacagt aagttcaagt gggttaaatg
    57361 gttttgtcaa ataatcatct gcaccagtca ttatcccttg tattttatcc atgtcttctg
    57421 attttgcact taacataagt attggtatat tcaaactttc tctaactttt ctacaaactt
    57481 ctattccatc cattttaggc atcattatat ccaataccat taaatgaata ttttcctttt
    57541 ttaaaatatc tagagcctct tttccatctt cagctttaat tacattatat ccactattta
    57601 aaagatatat ctctataagg tctcttattt ccttttcatc atccacaaca agaattgtat
    57661 tcttcacttt tacacatcct aacttaatct ttgtatatag ttttattcat ataaaattat
    57721 actatatttt agttagtgta atctataaat ttattcattt ctaaatttcc aatataatac
    57781 aacttattta catatttata ttatttgttt tgtaaatatt cttctaaagt taatcctttt
    57841 gaataaattt cctcggcagc atccttacca acatatctaa tatgccatgg ctcatatgct
    57901 gtacctgtta tatcttcttt accttcagga tatcttatta taaatccaaa cttgtgagca
    57961 ttttctgcca accatttagc ttcttttgta cttccaacaa accatctttc tggatttgtt
    58021 aaatcaatac aaagtccagt ttggtgctca ctgtaaccag gctttgctac atatgcatct
    58081 gccttttctc gcccctgaga ttttaccctt cttgtataag tatccagttg agtatcataa
    58141 gatctgtatg ctgaagaccc taaaaactgt attccttctg aattagcttg cttaactaaa
    58201 tcttcaactg cctttgcagg ttctcctgcc atttgttttt cttcctctgt tgcttcttca
    58261 acaaaaggta tgtttacctt agtaatattt tcaggagtat agtttttact aattccattt
    58321 gtcttgttta ccaataatat atttgatata ctatttgagt gatttttatt ttgagaattt
    58381 gcctcaacat cttgttttga ataatgttga gcaattactg ttggttcttt atctttctta
    58441 agtaatctat ctttagatat aaatacactt ataaatacta ccaaaataat agctactatt
    58501 aatttaaatt ttttcataat taaatattct ccttttcatt atgtttgtct ataatgttga
    58561 ttttagagta taagacttaa gtattttata agtaaatctt aaataaatct taaatttaat
    58621 attattaaag gatggtgata aaatgtctat acaaaaactt ctaagtaaag ctcgtaaggc
    58681 tatacaagat tttgatatga tacaagaaaa tgataaaatt gcagttggac tttctggtgg
    58741 aaaagatagt ttaactctac ttcatatact taaaagttat caaaggtttt ctccacaaaa
    58801 ctttgaattg atagccataa cattaaatac tggaggtgtt gataattctc cactagataa
    58861 attgtgtaaa gagataaatg ttccttttta tgaatttcaa actgacataa aagaaatcgt
    58921 atttgatata agaaaagaaa agaatccttg tgcattatgt gctaatctaa gaagaggtgc
    58981 tttgaatgat aatgctaaaa aacttggatg taataaagta gctcttgggc atcataaaga
    59041 tgatgcaatt gagacatttt taatgtctat gttttatgaa ggcagagtaa attgtttttc
    59101 cccaaagaca tacctagata gacaggattt gacggttata agacctatga tttacataga
    59161 agagtatatg actaaaaaaa tctcaaaaga ttctaactat cctattataa caaatccatg
    59221 ccctgcaaat ggtcatacta gaagagagta cataaaaaat cttattgcta atttaaataa
    59281 agaaatgcct gattttaaaa gaaatgtatt tggtgctcta aataattctg agaaattatt
    59341 tatatgggat aaagagaaga taaaaaattt taaatagtaa ttaaaatttt taaataaaaa
    59401 agaaagattg tattaattgt aaataatctt tatataatct acacaatctt acttttttat
    59461 ttattatatg ttattatttt taatctatat tttaatagtt attaatagta tttattttgt
    59521 ctaatacatt aattataact taaatatttt atatattaat ttaatctatt aattcattca
    59581 atctactagt ttaatctatt tttacagtat atacatttac atattataac aaacaaaatg
    59641 atattttcta aatattttat gttagattat aatattaaat tctattatct ctggtatatt
    59701 aaaaaatcta aatggtaact ttgtgcttcc aagacctgaa ctcacatata aatgatttcc
    59761 atttatatca taaaaccctt tagtatattt tcttccatat ggaggagtaa ctaatgctcc
    59821 cttaataggt agtcttattt gaccaccatg actatgccca gataaaacta aattcattgt
    59881 atatttacta agcatgtcta ctaaatctgg ttcatgtgct aacaataaat taaaattctt
    59941 attatctatt tgactctcca gatattttat attaggatgt ccatttaata tttcatcaac
    60001 acctaatata ttaatatact tattatcttt taattttatt tttttatttt catttactaa
    60061 aagattaaag tcggaatttt tcataatctg cctataatac ctaggaagtt tatacatata
    60121 atcatgatta ccgaatactg aaaattttcc caacctagca ttcatacttg ataaaatagt
    60181 tgtaatttca tctacatttg gatttttatt ggagtaatca atcaaatcac cagtaaatac
    60241 tattatatct ggattcaaag tattaatctt attagccact tttttgagat tcttagttga
    60301 gtaaaaactt cctatttgag tatctgaaat ttgaactact tttatacttt cagatttact
    60361 ctcaattata tcatttttta tcaatgttcc attttcactt atattatatt ttttcacaat
    60421 taatagactc ggctctattg caactgagta tacaaaaatc aaaataaata ttaagataaa
    60481 aaattttaaa aaatacttaa tttttgagtt caaaatatct acctacttat ttattttttt
    60541 aaactatttg cattacagac tcaactttgt tcatttttct gtcatgcatt tttggcttat
    60601 ttgctgaaaa ccacttatat gttgctgtaa gaccttcttt tagtaacaca tttggtatat
    60661 aaagcccatg ttcaataagc ttatttatat caagattaaa gtctatattt ctaaatggga
    60721 aatacgttct ttctctaaac tctacttttt ccatatctac atattttatt ataggttctt
    60781 tgccaataac ttctccacac gtatatataa ggtcatccca agaaattaac tgtggattcg
    60841 tcacattata tgcctctctt acatgaggat ttttcattat actttctaat acctttacca
    60901 aatctccaat atatataaat tgattactaa cttgttttcc ttttggtact ggtatctttt
    60961 catttttttc tattttttca aagaaataat actctctata taaattatta ttttcaccat
    61021 atatgtaagt tggtctaata attatatatg gtatagggct atttataaca aaatcttcag
    61081 cctctttttt atttaaccca tattttcccc agttttcatt ttcacctttc tcattttctt
    61141 cttttatatt tcttccacta tctttatata ctgctcctgc tgacaatact atatactttt
    61201 ttaagctatc catacttata aaatcaatca gattacttac atcttctttt gtatatgctg
    61261 tcatatcata tatgtaatca tattttcttc ctgtgataat gttttccata tcttttcgaa
    61321 cttttctatc acaaattaga tgttttttaa aacccttata atctatttcc tttttaccat
    61381 ttgtaagtat atcaatttga tacccacatt taatcaaacg cttagcaagt gcagaaccta
    61441 tgaagtcgct tccacccata attaaaatag atttcatttt aagtgcatcc tcctcttttt
    61501 taaatgactt ccttaactat aatatcatat ttttaaatat gcgacaccat tttgtaatat
    61561 ttttgtctat aaaagatatt tataacaaaa tatcttttat agactctaca ttttcgacaa
    61621 gataagtagg ttcactttca ctaagctctt caaaagaacc atacccatac aacactccaa
    61681 tagaatctat gcctattttt ttagctccaa ttatgtcata ctttctatct ccaaccataa
    61741 taactttatc tttatctttt acattacata ggtctagtac atattgtata acttcatttt
    61801 tatttactct tgtaccatca agattgctac ctgctacata tttaaaatat ctatctatat
    61861 caaaatatct aagtatagtt tctgcaaaaa ccgttggctt agaagttgct actaataata
    61921 ttttaccttt tttatagagc atttctaata tctcttttat attctcatag attttatttt
    61981 caaatatccc tttatcagta aaatattctc tatacttttc aacagcttct ttagcttttt
    62041 tatcttcaaa tttataatac tctttaaaag tatcgtataa tggtggtcct ataaattgtt
    62101 ctaagttttc caaatcttct tcaataccaa aactatttaa agaatactga atagactttg
    62161 ttattccttc tttagggtct gtaagtgttc catctaaatc aaataatact atttcataat
    62221 ttttcttcat atttcagtcc tccatactta taaaaaataa taccctatat tttaagttta
    62281 tctattttaa aaagctatag taatagaaat ttctaatact atagcttaag tactcaatta
    62341 aatcttatat atttattttt aaaataaatt taaacaactc tatttaactg ttatagctga
    62401 aactggacat ccttcttcgg cttctttaca taaatcttgt aagtctgctg gtatttctcc
    62461 ttcaattgct actgaatgcc cttcatcact catactaaaa acgtctggac atgttcctat
    62521 acatgctcca caagctacac atacatcctt atcaacaaat gctttcatac taaaatacct
    62581 cccctaaaat tattattttt taattgttgt ttccttagat atttatccaa tatatgacaa
    62641 tttaaacata tatttattat tttatcacta ttgtttaatt tattatagta ttttcgtatc
    62701 catgtctata aacttcactg cttttcatcc atgattttac agtatattgt aatcttaatt
    62761 ttttatttaa aatgagttca ttattattat agtcttttat tatatcatta ctcttttcca
    62821 ttgtgaatat tgtaaaatca ccgtctccac caatccttat tcttccttta ttttcatgta
    62881 aatcgaaaat ttttgttgga tattcagtta ctttttctat gcacttttct aaggatatgc
    62941 caagttccat aattttattt ataacattta aaagagaata atttacgtct ttcatgtttt
    63001 ttatatgcat atcagtactt attaggtctg gctctaaacc ttgctttatt gcttttttaa
    63061 atactttaaa atcaaattgg tctaatccat gacatacatc aaacaatact cctctatcct
    63121 ttgcgtttat tactgatttt cttaatgtac cagatttttt aaggattcca tttgtactat
    63181 tcccatatac tggtgtaacc acatctcctt ttcccaaaat attcattact tcatctatat
    63241 atgatggata ctcacctata tatactacta agggtaagtt taatttctta gcaacttgct
    63301 ttgatttctt aattatatct ataccatttt tattagattg aaatttactc gcttttactt
    63361 ttatcccctt tatcttttct atattttttt ctacaactga ctcaaccttg tcaaaattta
    63421 taacatctaa agaagttgat tcattcaata tatttagtcc ctcatttgta acatttaaaa
    63481 aagaatatac ttctgtttta cactcatcca tatacttttt tttaaaatca tagtagttta
    63541 aaggaccagc tgtacctgca tcaaatataa ctgtagaacc tttttcaatt ccaattgaat
    63601 cagaatccat acctgtaggt aattttctct tataacaatg ggtgtgaaca tctataaatc
    63661 ctggggaaat atacatatta tcagcattta ttatctcgaa ctctttattt gtaagtaatt
    63721 tttcttttct tattttttct ttaaggttca atccaatagc atatattttc ccatgtaaaa
    63781 ccaggatatc tcttctttca aatttgatac catctgttgg agatattatt gtcccatttc
    63841 ttataagtaa atttttcatt tattccacat cctaattaca atataattta tctaatagtt
    63901 tttcttacat aaataaaata agcctaaaaa taaaaatatt ttagacttat tcactatatt
    63961 atactatatt aattaaatta aataaaaact ttaatttact ttaagaagca attaagtatt
    64021 tgttgctcgg cttcttcttc agtaagacct aatgtcatca tctttagtat ttggtctcct
    64081 gcaatctttc caatagctgc ttcatgtact aaaagagcat ctgggtgatt tgcagcaatt
    64141 tcaggtatag cactaatttg agaatttccc ataattattg aatcacattg aacatgtgca
    64201 gaacaaagag aatccccaat aacacaagga ttaaattttt gcttagaatt atcttgccca
    64261 actgtacgag aaactacttg agcagaagag ttttccccct ctaagacaac cttcatatta
    64321 gattctgcaa cttgattacc atgagttaat aatttctcaa atacaactat tttagctcct
    64381 ttacctaggt tagcatccat ttctctttta gttgaatcta cacccttaat ttgaattgtt
    64441 tccatctcac aatatgaatc ctcatccata ttaacaatag taactggatt taaaattctc
    64501 tttcctttac catcaccttc accataatgt ttttctacat attttaggcg agctccttta
    64561 cgtaagaaaa atctatgtat accattatgt tcactatcgt cacaaccaca gttatgtata
    64621 ccacatccag caattataac aacatctgca ttttctccaa tttcaaagtc attatatacc
    64681 atatcctgta caccagtatc tgttactatt actggtatat gtacattttc tccttttgta
    64741 tttggcttta ctataatatc tattccaggt ttatcagttt taggaattat agttacattt
    64801 tcagttgaat gtctctctac tccttgccca tttttacgta tattgtatgc tcctaatgga
    64861 gttccacgaa gttcagcaac tttttctaaa agatttaaat ctattttgtt catttaattt
    64921 gccttccttt ctaattaatt catatctttc attaattcac agcttgaatt aacttgacac
    64981 atgatttcag gtaatatagc ctcttttgtt ccatggcttt ttactgaacc atcttgtaga
    65041 acaattattt catcagctaa ctctaatatt ctttcttggt gagaaattat aattatagtc
    65101 tggtcagact cttcatgtat tttcttaaag ctttcattga gtttgccaaa gctccaaagg
    65161 tctattcctg cttcaggttc atcaaatata gaaaccttta aatctctagc aaaaagagtt
    65221 gctatctcaa ttcttttcat ttctccccca gaaagagagt tatcaacttc acgatttaaa
    65281 tagtcttttg aacacaatcc aacatctgta aggtattggc aacatacatc agtagacaat
    65341 ggttttccat gagcaagtgt aagtaaattt tcaactgtca taccttttat tcttggtggc
    65401 tgttgaaatg catatcctat tccttttttt gctctttctg taatactaag atttgttata
    65461 tcttctccat ctaaaattat ctgaccacta gtagcttttt caattcccat aataagctta
    65521 gcaattgtag attttcctcc accatttggc cctgtgataa caataagttt tcccttctca
    65581 aatgaaaggc taacatcatt tattattcct agttcctcac tgttagactc aacattaaag
    65641 gaaagatttt ttatttcaag cataataccc ctcttttctg taaaatatta cattaatatc
    65701 cattctttta ttatatcagt aatttttata tatcagcaac tctaagcaga taaaatgtgt
    65761 attaaataat aaaacaaatt tattgaaaag taaaaaagat gagttttatg caaactcatc
    65821 ttagaaattt agtatatcat cttatatata tttaaaaatt aaccttctat atactctaat
    65881 attatttttt gattatcttt taacataatt tcttcttttt tagattctat tccattcttt
    65941 tttatcttta cctcagctac aaaggcatca ttaccttcaa ccatttctaa tagttcataa
    66001 gcctttttac gacctatttt agttgctata tcttttagta ctgccatttt cttaaacatt
    66061 ttatcacctc tactcaaaat ttacacttaa tttttaatta tataactcta attctggact
    66121 agtttataat aattattgtc tctaattata tcagatattg agtaaattta atactttgta
    66181 aaattattta tcctctctga ccaaatagtc atttccatct tggtctttaa aagaaaatat
    66241 ccttccatat ggcatttcca ttaattctcc aacctcaacc tcgttatttg ccatttgttc
    66301 ataagttcca ttaatgtctc ttgtacttaa aattattgat ggatgagata catttatctc
    66361 tttgttttgc ttcatcatta gatttttatc atacaacaca aatgttgtaa attcattttt
    66421 acttggtgca acttctaccc atttcatatt tggacccatt tccttttcat aagttaccac
    66481 aaagttcaat ttttctgtcc aaaacaactt tgcatcctct tgattattta catagagagt
    66541 tatttttcct attttattta tcataacaat acccaccttt attattaaat aaatacctaa
    66601 tattttttat atttaataat atacccatat atattatttt ctatagatat atatttctaa
    66661 tatttatcac caaattatgt aattctgctc aatatataat ttatagtatc catattatta
    66721 taggctttat ttatgcaatt taatcacctt atatatcata cttataatta tgataataat
    66781 tacataaaaa atcactccta aatagagttt tctatctaaa agtgatttca tatattctat
    66841 gcaattttgt gttttagcca ctttgttcct cttaatctta aacaatataa agttcctctt
    66901 acaagccaat cagtatacat acctatccaa attcctaaca ctccaaattc taatacaacc
    66961 cccaatacgt aacctgtaaa aattctaaaa atccacatac ctattactgc agtcatcatt
    67021 gtatatctag tatcaccagc cccctttagc cctgctgata atacaaagga tataggccat
    67081 attaccatag ctaaacaatc acttcgaatt aattgtgttg aaatgtcaat tacactagca
    67141 ttttgagtat acaaacttga aatccaaggt gcaattggta caaatatagc tcctactaca
    67201 aataaacaaa ttgttgcaaa tttagttaaa tataataaag tactcttagc tcctttaata
    67261 tctccacgtc ctatatactg tcccaccaaa gttgtggcag acaaagctag agcattccca
    67321 attacattta ttatggatgc aattgacatt cctattgcat tggatgcaat tgctgatgtt
    67381 cccatagtaa ctataaatac ctgaacaatc aatttacctg cattaaaaag tagttgttca
    67441 actccagctg gtatccctat attaaatata gacttttgag tttcaacatc aatcttaaat
    67501 ggaaatattt tacctataga tataaattca tttcctttaa ataaggctct tacaataact
    67561 atacatccaa ttattctggc tatggcaata gacatagctg cacctgttat cccataggat
    67621 ggtgtttgta aatttattcc tagaggattt aaatcaacac catatataag tatatatcct
    67681 aatgttacat ttactatatt cataaacata gtcacataca taggtttctt tacatctcca
    67741 caacccctta gaataccatt tgctatttgt tgtatcgcaa tgaatgggta tgtaaacaat
    67801 gtaaactcta tgtataattt tgcatttgat tttaccaatt cttctgctga accataaaat
    67861 aaattaatta cacctgttct aaaaatccac attaatattg ttattgtaaa ggataatatt
    67921 gctccagaca ctagagcctg cttaatagtt tcattcactt tttcattatc ttttttccct
    67981 atttgttgag ctacaacaac agtagctcca acagataatg cagcaaatac agatataaat
    68041 atattgttta ttgaatcaac cattccaact gcagatacag cttcttcccc aatatgacct
    68101 gccatcattg tattaaatac ccctaaaagc atgacaaacg tctgctctat cattatagga
    68161 attgctaact ttataacatt tttccttata aacatcccta ttcctctttt ccctctttat
    68221 ataaatttaa tttttaatta gtttatcgaa ctgtaaattg ataatacaaa gtttaaaatt
    68281 gtattattag catcataata tattgctttc aaataatata aatcttgttt aatataattt
    68341 gaacaccgta tatctttata attattctat gtttattatt ttttatggct accacattta
    68401 aaatattaca tttagatgta acaaaatcgt ctccatttaa atattgtatt ttataaacta
    68461 attttaggat gtgatacttt ggttaattta aatgaaaata atctaaatgt aaatatggtt
    68521 tatcctattt ctcccacagc acccatacgt ttcagaagat atactgtttc atatttagaa
    68581 aacatggaaa atatttattt aactatagca acatactttg atacgattgg tttaggcaca
    68641 atgaatatcg acaaagttta tggtcagtgg gcttggttta ctgatactat atatgatttg
    68701 aatctatttg tttttgtagg aaattatcct tatcaaattg ccaaaaacag atatgataca
    68761 tttgtaaata ttttaccagt ggctattact tctattgtca atggagatag agtattttta
    68821 atttcaaatc cttgtctgtt aaattcaaaa attacagtta gatttatatc tagtcatcct
    68881 actcttaata gaacagttga ttatggcaat attagagatt ttatttttta acactacaac
    68941 atgatgtgct attaaaaaat atcctaaatt taatgatact attaaataac tagaatattt
    69001 ttaattggca catcatgctt agctattata aattcataat attatttttt taagataagt
    69061 actgtgtttt atctacttat ctatttttat ttacctagtt tctcagttct atatcctatt
    69121 tctttattag ccagtttata gccttcttgt atcatttctt ctcttgttaa tgcactccct
    69181 aataaattgt caatactcag ttgctttcta tcagcaaaat acttatccaa taatgattcc
    69241 tctatatctt gctgatatgc caaatttcct tcatgcatta tatattttac atcaaaacct
    69301 tctttattta atatttttcc taccaaaata cttctatggc atcttatagg ttcttgcata
    69361 gctcctaata aaactatcct ataacccatt tgacaacctt tttttaatct atctattcct
    69421 tttaaaaaaa tatcttcttt tgctactttc tcaaaatctg cataaccttc ttgtgtatat
    69481 acatctttat tagttctttt agctccaaat tcttttccca tgtatatata tacaaatcct
    69541 gaatttctaa gagattcgtt gaatgcctct ttattgtatt gagtattata tttagaatat
    69601 ggagtttctc taatgtcaac tacacaattt atgtcatatt tttttatcat atcaataagc
    69661 ttatcatatg gataatttga atgtcctatt gcgaatattt ccatataaat atcctcctat
    69721 tctttaaaat tagtatttat atatatgtat acccgattta tttaaaatta aataaagcat
    69781 tactttaaat acccaataga ttttttcttg atactttaca ctttttactt tatatcctta
    69841 aaaaatatac aactttatat ataaaacatc aagatttatg catattttgt atattaaata
    69901 taattattta taaaaattta ataaatagaa catctttaga aaactattat aataaaaaaa
    69961 taagaggctg tctcaaaata gagataagct ttttttcatc attgaaatta taaaaatata
    70021 cttgatttca tatgaaaaaa ggtgcctcat aaactaaaaa attcattttg agacaccact
    70081 tttttattct tatttatact ttgtatacat attataatat gcgtttcact ggtatctgaa
    70141 cttctgtcaa ccaatcttct tcactctctt tattccatat accatctata taagattctc
    70201 tgggatttcc aaccacttta tatttattat cctctatcca tttaaatgca tctgcgtaag
    70261 tttttcccaa tgttgaatat gaaccattgt gtaatataca aacagcactt tcaacttcat
    70321 ctagttcttt aaattttaat atatctgtat cttcttttaa atcatttata gcttgacaca
    70381 tctcaacatc catattggtc tctctgtatt caccatcatg atatatattg aaacaataat
    70441 ctggaactgc acatgtacac tctgacttca tcatttcttc agccattaca tttggaaata
    70501 gattaaaaag ttcatcatac ccctttaata cctttctcat agaggcaatt ttaacttttg
    70561 gtaaagactt aataattaca tcattcatat tgacttctcc tttcaaattc acaaggtaat
    70621 tacgcagttt aatgagttta tattcttcac ttttaattac atctaacatt tctttttctt
    70681 tattctttaa aatattttca acctcttcag gattttctat agcttctttt atctcagcta
    70741 atgacaaacc catttgtttt aaagttatta tctgatgtaa tttaggtaat tgctctgtcg
    70801 tatagtacct atattttgta aactcatcta catactctgg ttttaacaac cctatatctt
    70861 cataatacct taatgtcttt gtagttattt tatttatttt agaaaacatt cctatagaaa
    70921 acatctcatc acctgcgcat tagatttgat taatttaagt ttagaccttc cccttaggtt
    70981 aaagtcaata cgaaataaat tataattgta ttaattcttc aattctatct ccacttaata
    71041 ccaacgtatc ccctgttttt ataacagttg agcctttagg cactaaaacc tgttcctttc
    71101 gttttatcat aactattaat atatcttctg gtatattaga atccattata ctcttatttg
    71161 cccacttact actatcatca acatttactt ctataagttt agagctaatt tctccatcat
    71221 aatcattaaa tgtttttaat acaggtgtat tatcatcaac taaatctagc tttctagcta
    71281 ctgctggtat caatgtacct tgtaccccta ctgaaagtaa agctataaaa aatattatat
    71341 ggaatatatc attctctatt attacacctt gagtaactgc ataaattgca aaaactactg
    71401 aggctgcacc tctaagacct acccatgata tgaatagttt ttctttattt gaaaatttaa
    71461 attttgctag tactataaat gttgctaatg gtcttgcaat aactatcatg aatatagata
    71521 tgaccattgc tataccaaat atatttggta gcttggaagg gaaagataac aatcctaaca
    71581 taaagaataa cattatctgc ataatccatg aaattccatc aaagaaatga accaaacttt
    71641 ttttatgagg tatcttgcta tttcctataa taatacctga aatatacaca cttaaatatc
    71701 catttcctcc gatatactca ctaaatgcat acgaaagtat tgcaatagct gttataaata
    71761 tagtataaaa tccttctatc tcgaagtttg aatgccttaa aatataaaca gataattttg
    71821 ctagtacaaa tcctatagct aacccaaaaa ctatttgttt tattaccatt ggtacaataa
    71881 gctctacacc agaattgttc atcaatgtca aaagaattag tgtcaacata tacgctattg
    71941 ggtcattact tccactttca acttctaata atgaggcaag tgaacccttt aagtttaatt
    72001 tttgagaacg caacacagca aacacagatg cagcatctgt tgaagctgca attgccccaa
    72061 ttaataaacc ttcaagtaaa ctagttccta ttaccatatg gcaaaatatg cctgtaaccc
    72121 cagccgtaat tattacaccc agtgaagaca tcaatataga aggtatagca acaggtttag
    72181 ccatattcca gtttgttcca aaccctccaa aaaacattat gaatattagt ccaatagagc
    72241 ataattgttt tgttaattca tagttatcaa aatagattcc taccattcca tcagacccaa
    72301 ataacatccc tagtaagata aaaatcaata atattggtac tccaaattta tacaatacct
    72361 tgctagaagt tatacaaatc aatagtacta acccacttat aatcattaat tctgtcatag
    72421 catcaactcc atttcatata aattttgtag attaatttac atctacaatt ttattactta
    72481 ttcaaatata atatgacata ggttttataa gttatagtgt ataaagtaca ataaaaattt
    72541 cacaatacat taaaatatga gtgttatact taaatttata tatttatttt aattatattc
    72601 atttaatagt tataatttga attttttttt attaatattt catttttcag t
//
LOCUS       DBGJFK010000011        67252 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.011, whole genome shotgun sequence.
ACCESSION   DBGJFK010000011 DBGJFK010000000
VERSION     DBGJFK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 67252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67252
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.011"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     regulatory      complement(125..208)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(441..1292)
                     /locus_tag="ACOIAP_000924"
     CDS             complement(441..1292)
                     /locus_tag="ACOIAP_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2637833.1"
                     /translation="MFKKKIGVLLASTILVGALAVGCGSNSGGSGNSGNSGDSSKVSV
                     SGSTSIGPLMETIGEKFQEKNKGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEE
                     KSAGLKETKIAIDGIALITNTANPIKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVS
                     REEGSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKV
                     NSLKINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQAIVSEK
                     GFIKVNQ"
     gene            complement(1545..3329)
                     /gene="pepF"
                     /locus_tag="ACOIAP_000925"
     CDS             complement(1545..3329)
                     /gene="pepF"
                     /locus_tag="ACOIAP_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGZ2637834.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSNKEEIEKDISKVKNLIQEVKEYK
                     GKLSDSKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDDKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTVPENVYDMLAYADMQFPEIEDEDGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVYRQTMFAEFEKIVHERVENGEPLTADEFTDIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(3395..4060)
                     /locus_tag="ACOIAP_000926"
     CDS             complement(3395..4060)
                     /locus_tag="ACOIAP_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGZ2637835.1"
                     /translation="MIDIGSKEIALRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGVAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKSQLIIRNMEIECRNEEYWKVNFFVSYAKRIHLQDVMKEINMIEGVINVD
                     YLD"
     gene            complement(4211..4372)
                     /locus_tag="ACOIAP_000927"
     CDS             complement(4211..4372)
                     /locus_tag="ACOIAP_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HGZ2637836.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(4450..4959)
                     /locus_tag="ACOIAP_000928"
     CDS             complement(4450..4959)
                     /locus_tag="ACOIAP_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HGZ2637837.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKGL
                     SIIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            5166..5384
                     /locus_tag="ACOIAP_000929"
     CDS             5166..5384
                     /locus_tag="ACOIAP_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGZ2637838.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            5402..7348
                     /gene="feoB"
                     /locus_tag="ACOIAP_000930"
     CDS             5402..7348
                     /gene="feoB"
                     /locus_tag="ACOIAP_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HGZ2637839.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLGEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIALNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFASFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIVEALIGGIIIALALFILFNKFKSTKNGSVCSGCS
                     ICSGCPSANSCSSKEDSNKKNSTH"
     gene            complement(7507..8562)
                     /locus_tag="ACOIAP_000931"
     CDS             complement(7507..8562)
                     /locus_tag="ACOIAP_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGZ2637840.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKKENLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGLISSEKYNDEINKILDAINRFEAVYKLSKQWIERNKKKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGIDPSI
                     PKDTKFHMKLGSKKLNK"
     gene            complement(8610..9410)
                     /locus_tag="ACOIAP_000932"
     CDS             complement(8610..9410)
                     /locus_tag="ACOIAP_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGZ2637841.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLSKEGNIFGPLLFLLLYNIPALALRIFGLKYGY
                     QVGVNSLDRIQREGLMDKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVAGIVLHAIGLL"
     gene            complement(9403..10194)
                     /locus_tag="ACOIAP_000933"
     CDS             complement(9403..10194)
                     /locus_tag="ACOIAP_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGZ2637842.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMFDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGITGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQRAVFYAKQADFKRVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKIILDGLGVAGTLLPAVGFALLMDMLFSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLIEGEIDFE"
     gene            complement(10229..10651)
                     /locus_tag="ACOIAP_000934"
     CDS             complement(10229..10651)
                     /locus_tag="ACOIAP_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2637843.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTKDKSADDA
                     EKEIRSILLNNKDSEAFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIIKSGLEEAKNGIVYVNELLENQNKIKNII"
     gene            complement(10667..11146)
                     /locus_tag="ACOIAP_000935"
     CDS             complement(10667..11146)
                     /locus_tag="ACOIAP_000935"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2637844.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVIAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDNDDINNFKEISDLGIDIEFRMLPRDKKKQLSNLIK"
     gene            complement(11278..14034)
                     /locus_tag="ACOIAP_000936"
     CDS             complement(11278..14034)
                     /locus_tag="ACOIAP_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2637845.1"
                     /translation="MRDEILSFVNECALFNNFDELKKESGIVTEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKSKINDVVGPTKKSIYESLDELKNECKLLKQEIV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YIPNIEERGSIEKRKIVEHFIYEESKVLGLPIEITQITLNTILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIVFSPKQFSIEM
                     SNGTNKRSIIYQSFIKCLDYFDRLQKNEITKERFSKKSSNLVTRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLIMNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNAII
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKSKINSTMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVLAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSGVVENEKIKSIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLPNDKKIALYVHLSCM
                     IERLVRQAEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQISISEIGYIYNIIY
                     GLPQ"
     gene            complement(14625..15428)
                     /gene="proC"
                     /locus_tag="ACOIAP_000937"
     CDS             complement(14625..15428)
                     /gene="proC"
                     /locus_tag="ACOIAP_000937"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGZ2637846.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAKDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVANSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKAMFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(15753..18122)
                     /gene="hypD"
                     /locus_tag="ACOIAP_000938"
     CDS             complement(15753..18122)
                     /gene="hypD"
                     /locus_tag="ACOIAP_000938"
                     /EC_number="4.2.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase"
                     /protein_id="HGZ2637847.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFKSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(18127..19035)
                     /locus_tag="ACOIAP_000939"
     CDS             complement(18127..19035)
                     /locus_tag="ACOIAP_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019471 - 4-hydroxyproline metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-4-hydroxy-L-proline dehydratase activase"
                     /protein_id="HGZ2637848.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSRCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIDKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKYADLFLYDIKLIDEEKHIKFTGKSNDLILKNVKVLSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTEIGG"
     gene            complement(19380..20459)
                     /locus_tag="ACOIAP_000940"
     CDS             complement(19380..20459)
                     /locus_tag="ACOIAP_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HGZ2637849.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVGKSTGSSTP
                     IIVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTNNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTTMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASKAEGLGFAIPINTAKSIVEEVIKTGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TLSKGASTKITVNRGGKAVTINVNF"
     gene            complement(20614..21963)
                     /locus_tag="ACOIAP_000941"
     CDS             complement(20614..21963)
                     /locus_tag="ACOIAP_000941"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGZ2637850.1"
                     /translation="MRKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDFLLVIGIGGSYLGSRAAIDMVSHSFRNR
                     LKKEQRNAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDSSKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKNNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITINSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            complement(22227..23855)
                     /locus_tag="ACOIAP_000942"
     CDS             complement(22227..23855)
                     /locus_tag="ACOIAP_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGZ2637851.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPIALGVGIILYLFGNNPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPILGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPIVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNFIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            complement(23978..25582)
                     /locus_tag="ACOIAP_000943"
     CDS             complement(23978..25582)
                     /locus_tag="ACOIAP_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGZ2637852.1"
                     /translation="MLRISNVKLGIDKDISLLKDIVLKKLRIKEKNLIKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILKSKIKDVTKIKEIRYINVPMGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVVINDTEKIDTDTIILAVGHSARDTYEMLYSRGVKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASTSNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGNVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSVRNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            complement(25630..25947)
                     /locus_tag="ACOIAP_000944"
     CDS             complement(25630..25947)
                     /locus_tag="ACOIAP_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637853.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGNEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            complement(25952..26317)
                     /locus_tag="ACOIAP_000945"
     CDS             complement(25952..26317)
                     /locus_tag="ACOIAP_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637854.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            complement(26398..27435)
                     /locus_tag="ACOIAP_000946"
     CDS             complement(26398..27435)
                     /locus_tag="ACOIAP_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C metal-binding domain-containing protein"
                     /protein_id="HGZ2637855.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSLFESYVSIYEVKEISAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKKERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            complement(27688..28272)
                     /locus_tag="ACOIAP_000947"
     CDS             complement(27688..28272)
                     /locus_tag="ACOIAP_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637856.1"
                     /translation="MRLNNREKNLLKILLILVIMVASDIVVNYLEENLTSLKNEKQNI
                     INKINNQDNYQIKGNKHIDDKYIESVELNENEELKNNFNNSFLDKKTNKDIVLLVENE
                     LKNIVNIEYINQESSLDNHNKKQVNLEIKVNGELENVLKFEDVMKKLRLNNKLEKIEI
                     NKLKVNNFDAQNILSEYKQEKDNIVECKMTVRVT"
     gene            complement(28287..28730)
                     /locus_tag="ACOIAP_000948"
     CDS             complement(28287..28730)
                     /locus_tag="ACOIAP_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637857.1"
                     /translation="MKVDKTINFLNGFKKTKSCNKVYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKHTISTTDKTREKFSKIKLNEIKKIYETIGINSITRIWIDK
                     NKLEIEGVCSDLDVLDNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            complement(28731..29603)
                     /locus_tag="ACOIAP_000949"
     CDS             complement(28731..29603)
                     /locus_tag="ACOIAP_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HGZ2637858.1"
                     /translation="MATIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFNIK
                     NDSNSIEKIKYIEDVVRFVKEEIDKSKISYKNLYFNIQIQDIVIRNVEVLDTKKKRDI
                     LSMIEFEITQYIPINISNYSIKYKVINSINDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIEETYLLSKERK
                     SYEFIKRLLRDFKYIYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDTDLE
                     DNSINYISSIGMII"
     gene            complement(29657..30007)
                     /locus_tag="ACOIAP_000950"
     CDS             complement(29657..30007)
                     /locus_tag="ACOIAP_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HGZ2637859.1"
                     /translation="MINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKLNAD
                     YTNAANIVTAASMAINDDENIIDSLSVEALKEKGYLNTVPVPQSTSGKFELVINDNGT
                     DISVNINSKQFYPK"
     gene            complement(30061..31146)
                     /locus_tag="ACOIAP_000951"
     CDS             complement(30061..31146)
                     /locus_tag="ACOIAP_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HGZ2637860.1"
                     /translation="MRLSKNIFCNLEKFYLVLNRISDKEIRVICKEIGILMESGCEIT
                     KIFEIIESQSSKKVKNLLNIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKIKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTSNG
                     IEPPLITRVLMGISTVVTNNLAYLIFSFILFSIGSIYFFITNDNIKKLTNSLKFKVPF
                     VKRINQLVATTRFSRALSILISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMTNTGEESGKLDKSLDVINKFYENELNNKIEQIMKFIEPV
                     LIVFMGLIIGIFVLAMVVPMFDAITSF"
     gene            complement(31317..32696)
                     /locus_tag="ACOIAP_000952"
     CDS             complement(31317..32696)
                     /locus_tag="ACOIAP_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HGZ2637861.1"
                     /translation="MIKIILEENSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVVKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDDFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            complement(32689..33369)
                     /locus_tag="ACOIAP_000953"
     CDS             complement(32689..33369)
                     /locus_tag="ACOIAP_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HGZ2637862.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKGKLDKEIDSMKKNQKNSEKISQIETLRDSLSYSDMKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKLNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(33972..35051)
                     /locus_tag="ACOIAP_000954"
     CDS             complement(33972..35051)
                     /locus_tag="ACOIAP_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2637863.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNRQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVNKVY
                     YLAGEIGTGKTTLLNKVYNKAIEKGLNVEVYHYPLIPEKIETILLTDLDIGITISTNF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDNLVKRILKYEENL"
     regulatory      35337..35452
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            35627..36997
                     /locus_tag="ACOIAP_000955"
     CDS             35627..36997
                     /locus_tag="ACOIAP_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2637864.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPTNEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQSKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGIIALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGSVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATVRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNKSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     gene            complement(37261..37872)
                     /gene="yihA"
                     /locus_tag="ACOIAP_000956"
     CDS             complement(37261..37872)
                     /gene="yihA"
                     /locus_tag="ACOIAP_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGZ2637865.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(37862..40225)
                     /gene="lon"
                     /locus_tag="ACOIAP_000957"
     CDS             complement(37862..40225)
                     /gene="lon"
                     /locus_tag="ACOIAP_000957"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HGZ2637866.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGKVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVISKSDLEAYLGKDMFKYQLAEVNPQIGLVNGLAWTAVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPDFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            40405..40917
                     /locus_tag="ACOIAP_000958"
     CDS             40405..40917
                     /locus_tag="ACOIAP_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HGZ2637867.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            40905..41432
                     /locus_tag="ACOIAP_000959"
     CDS             40905..41432
                     /locus_tag="ACOIAP_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HGZ2637868.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATVGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(41501..42751)
                     /gene="clpX"
                     /locus_tag="ACOIAP_000960"
     CDS             complement(41501..42751)
                     /gene="clpX"
                     /locus_tag="ACOIAP_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGZ2637869.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(42770..43354)
                     /gene="clpP"
                     /locus_tag="ACOIAP_000961"
     CDS             complement(42770..43354)
                     /gene="clpP"
                     /locus_tag="ACOIAP_000961"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HGZ2637870.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(43504..44790)
                     /gene="tig"
                     /locus_tag="ACOIAP_000962"
     CDS             complement(43504..44790)
                     /gene="tig"
                     /locus_tag="ACOIAP_000962"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGZ2637871.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(44984..45454)
                     /locus_tag="ACOIAP_000963"
     CDS             complement(44984..45454)
                     /locus_tag="ACOIAP_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGZ2637872.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTHMLEKKATEIDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDNINIEEIRI"
     gene            complement(45454..46803)
                     /gene="rph"
                     /locus_tag="ACOIAP_000964"
     CDS             complement(45454..46803)
                     /gene="rph"
                     /locus_tag="ACOIAP_000964"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HGZ2637873.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTVKEMPITNFV
                     SAISVGIVNGTHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRTDLNLL
                     LELGEKGNKELIRLQKEALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIDIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            complement(46962..48986)
                     /gene="ligA"
                     /locus_tag="ACOIAP_000965"
     CDS             complement(46962..48986)
                     /gene="ligA"
                     /locus_tag="ACOIAP_000965"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGZ2637874.1"
                     /translation="MSIKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEDYDLESHSDSLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLEYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVELERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDDVMSATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLAKANDLGIKVIDEERFLELLKLSSKDEVKAILES"
     gene            complement(49173..50111)
                     /locus_tag="ACOIAP_000966"
     CDS             complement(49173..50111)
                     /locus_tag="ACOIAP_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HGZ2637875.1"
                     /translation="MKVLFTINYGKEKFDKIRDLGYDVIHYSEDIIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGLE
                     IWGVNTAGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECIEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYILENKPVDNVVDISRGY"
     gene            complement(50213..50635)
                     /locus_tag="ACOIAP_000967"
     CDS             complement(50213..50635)
                     /locus_tag="ACOIAP_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HGZ2637876.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGDNIIRDILDGNISSECENGIKSKSVIFNNAPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            50823..51413
                     /locus_tag="ACOIAP_000968"
     CDS             50823..51413
                     /locus_tag="ACOIAP_000968"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2637877.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLSTQGYSRSYLIFGIVALIVGIPVMYIR"
     gene            51728..52000
                     /locus_tag="ACOIAP_000969"
     CDS             51728..52000
                     /locus_tag="ACOIAP_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637878.1"
                     /translation="MQYLLIIIIGLLLFIEVDKLKKQVKSQQKQIDTLCEQTGNNQLA
                     TYHISDEDKELILHLKNSGKDVEAVKKVREITAMELEEAKQYVDSL"
     gene            52056..52253
                     /locus_tag="ACOIAP_000970"
     CDS             52056..52253
                     /locus_tag="ACOIAP_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGZ2637879.1"
                     /translation="MDKRHWFLLGYLIIPVCFFVAVIVVGLLRSHSLIEIYNDGLGIT
                     ALYYLLLSLFVYIRWQYFSDK"
     gene            52274..52459
                     /locus_tag="ACOIAP_000971"
     CDS             52274..52459
                     /locus_tag="ACOIAP_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGZ2637880.1"
                     /translation="MYIIYTVLAAIVGMALVVTVDMGITKIFDKKSIFQKNYIKMPLS
                     YFIGIFVFLLIVRLIFS"
     gene            complement(52525..52833)
                     /locus_tag="ACOIAP_000972"
     CDS             complement(52525..52833)
                     /locus_tag="ACOIAP_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006426016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637881.1"
                     /translation="MKKKLLFATIILVLLAGILYYISLPDYLVFNSMSFSNGANRDTE
                     LQVIVYQYWNTDEVVAEIEAEHNQINGTPTTLIINLYHSKWSFHNGYEPFYSTIINYD
                     "
     gene            52947..53162
                     /locus_tag="ACOIAP_000973"
     CDS             52947..53162
                     /locus_tag="ACOIAP_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637882.1"
                     /translation="MKYGHLELHIEELLKEKGISKNTICKELDIPRSNFNRYCRNEFQ
                     RLDAQLICKLCSYLDCGIEELIEYVKE"
     gene            complement(53355..54038)
                     /locus_tag="ACOIAP_000974"
     CDS             complement(53355..54038)
                     /locus_tag="ACOIAP_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637883.1"
                     /translation="MNTIAERIKFAMKAKNKKQVDIVKDTGISKGAFSSYLSGQYNPK
                     ADKMELIADSLDVDLRWLYGQNVPMEHTSQNDNALQYVFYNNSCSEYLLDDLDDIYIA
                     MMTQYAALIPRFYVLVNRAGNAMHILPLFLKEDSSQFYECPSDFFYSDRHTIFTRDFE
                     SIHMVLTTATIYYYGIDTKTYEPKVTMLSYSQADDCFHINNGIQGGHIKAFEKELMKE
                     ALYLKHNDQ"
     gene            54287..54616
                     /locus_tag="ACOIAP_000975"
     CDS             54287..54616
                     /locus_tag="ACOIAP_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637884.1"
                     /translation="MQITLTKEQVKEAFGELRFMGADNCYRYDKDSKKKTEEVEALKL
                     HLGSMKLGNSVDIRLEATELPKIEPYAVVELEESVYAPYVQRGNFPVLVEKITCKGIR
                     PVPNKNM"
     gene            54702..55784
                     /locus_tag="ACOIAP_000976"
     CDS             54702..55784
                     /locus_tag="ACOIAP_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015554187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGZ2637885.1"
                     /translation="MGNLEERSGSFLPELPYTNRGVIRQKEALSALIDWCQITIKEVP
                     LEAVIEDVLRIPLELMTVTGYEKGIAGHEVVAIFDNIKVLKPTGNAQYQGFQILMSGK
                     GCRNYENFLQLNEETWFDFLNRVCQYHINVPRIDLAIDDRKPYLSIPDLIVRTKEGLL
                     STKLREIDFHDSGELKEEVFQSKGGSLYLGSSASNLRLVFYEKGYEQNKKYGTELDEN
                     WNRYELRFRQEMAVSVVQELLRYRDVAGLAMEVLNSKMRFLEKPTDSMTTRKRLYPTY
                     QAWAELMKDIGKVKLTMQPQKKSLQKVWKWLEKYVAPSLKLFAEVGKIEQRDYIGNLV
                     KNGEMNIAQKQLYDDYIKARKLDERG"
     gene            55804..55986
                     /locus_tag="ACOIAP_000977"
     CDS             55804..55986
                     /locus_tag="ACOIAP_000977"
                     /inference="COORDINATES: protein motif:HMM:NF020602.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGZ2637886.1"
                     /translation="MNLKEVSEYLGIGETKTRELLRDRNCPFSMKIGYRWYANKKILD
                     KWVQEQSEKKGGNYSI"
     gene            56072..57346
                     /locus_tag="ACOIAP_000978"
     CDS             56072..57346
                     /locus_tag="ACOIAP_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007863506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2637887.1"
                     /translation="MGKSLKGKELGAGLYQRKDGKYCGRFYDRFGIRRYVYGKTISET
                     KEKLNTAMYEDKMEMNVADNTVTLDEWYQKWLEIYKYKVIAPSTRVQYESIYKKHIQT
                     DFGHMKLKDIQPLQIRGKLVNLDKKGFGYETQNKVRILLLDMFNKAVADNVAMKNPVR
                     NIKVVRDEEKEPRVLSTEEQSAFFDTCKGTFYDNLFNVAISTGLRPGELYALEAEDLD
                     FEKKVIHITKSLSYQKFEGDTGKTFHMGKTKTKSSYRDVPMNRRCEIALKKQLLQKRV
                     VSGRNGAKTLKGFENLIFTTKYDTPLNAQIYADAIKVIVEQINLMREELEQFETFSGH
                     CFRHTFATRCFEAGIQPKTVQKYLGHATLQMTMDLYTHVLENHLSDEMDKLDSRLEMI
                     ELSSDDLAEQRFEREYRKQNEVLSSDKLIRIG"
     gene            57476..58165
                     /locus_tag="ACOIAP_000979"
     CDS             57476..58165
                     /locus_tag="ACOIAP_000979"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2637888.1"
                     /translation="MPKDVNEKVKSKGKKEKASDTISPSVWGYTLKEAKKIKYFWIMT
                     IGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVGSTFALFALIGNLFGGLLFDKFGQI
                     KPLIISFVLVLIATLSLLLVDKSSAFAFVFAILKGLSVFAYMIGPAYLTGTFFGQKEF
                     GSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFSWSIIILSVIIAYTLLIITSIGMKK
                     LNKERLDKLMQ"
     gene            complement(58241..58756)
                     /locus_tag="ACOIAP_000980"
     CDS             complement(58241..58756)
                     /locus_tag="ACOIAP_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2637889.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(58756..60132)
                     /locus_tag="ACOIAP_000981"
     CDS             complement(58756..60132)
                     /locus_tag="ACOIAP_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016695 - oxidoreductase activity, acting
                     on hydrogen as donor [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase, group A"
                     /protein_id="HGZ2637890.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(60157..60708)
                     /locus_tag="ACOIAP_000982"
     CDS             complement(60157..60708)
                     /locus_tag="ACOIAP_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2637891.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIIKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYQDGKEVEQVILDENKKIAYKCDLCKDSEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(60745..60918)
                     /locus_tag="ACOIAP_000983"
     CDS             complement(60745..60918)
                     /locus_tag="ACOIAP_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637892.1"
                     /translation="MCTKKEELKYSKCEICGVLINDTDKVYNNTYNLCKKCKRNMSIE
                     KILKYINIYDEGN"
     gene            complement(60929..61762)
                     /gene="fdhD"
                     /locus_tag="ACOIAP_000984"
     CDS             complement(60929..61762)
                     /gene="fdhD"
                     /locus_tag="ACOIAP_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HGZ2637893.1"
                     /translation="MNNIYSKTKLQQNSKDKVFENSYSLVEHKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNNKYINTFLCTPSNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIHEKQKNQNEQIIFLNSLDYITCAPVESNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSIFNFDKRIVTCEDVARHNAMDKAIGFCVLNDIALKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(61811..63955)
                     /gene="fdhF"
                     /locus_tag="ACOIAP_000985"
     CDS             complement(61811..63955)
                     /gene="fdhF"
                     /locus_tag="ACOIAP_000985"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(63539..63541),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HGZ2637894.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYAASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIEAQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAKKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYKSLKDKMTATNI"
     gene            complement(64206..65264)
                     /locus_tag="ACOIAP_000986"
     CDS             complement(64206..65264)
                     /locus_tag="ACOIAP_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HGZ2637895.1"
                     /translation="MDRLKSIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPQKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            complement(65475..66134)
                     /gene="cprR"
                     /locus_tag="ACOIAP_000987"
     CDS             complement(65475..66134)
                     /gene="cprR"
                     /locus_tag="ACOIAP_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HGZ2637896.1"
                     /translation="MSKILVIDDELDVLKLIENVLKRDGHEVKVISDIENAMDIEFNS
                     FNLIILDVMMPKMDGFEVCKAIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVLIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHVKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            66444..67073
                     /locus_tag="ACOIAP_000988"
     CDS             66444..67073
                     /locus_tag="ACOIAP_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HGZ2637897.1"
                     /translation="MDEKIRSSNYNVPFDYARKKFKELDPHTISNLSNISFNNDSNKF
                     ILNFFDRQYIIDYPSGEVWNDDGSICKNFELKILIIRYLTNAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLSRLSEVFTCQIDKYKLVMENMGAEKVDMGDLAYKFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIIYYFNAEDLAVVPDTAIDAILNKINQL"
BASE COUNT        21148 a        11681 c         7932 g        26491 t
ORIGIN      
        1 tggctacttt aaaagccaaa atttcaccta tcaataaaaa tcttaacgac gaacactctt
       61 tttttcaaat ttttcaacat ttttgttaat tttaaaacaa aaaaagacta tgcaatataa
      121 aaattatatt catagccggt tgcaccacta actccatata tctctagatg cccaataata
      181 agatatactt ctcagtttct aaaatatttt tattaaaaat cttttatata ttttcataaa
      241 tttctttttt attctaacat tgtaatatta ttttgtcaat atttccatat ttttagatat
      301 aaaatactaa aatatatatt ttatctaaag atatctttat ttttacattc aagaatagac
      361 aataccctgc aagttaaagc atcattttta tgagcttatc tcacagggta ttatacatct
      421 actttatatt ataatttatg ttattgatta actttaatga atcctttttc tgaaacaatt
      481 gcttgtcctt catcacttaa tatataatct attaaagctt tacctttttc tgataaaccg
      541 tcttctttat taactaatat aaatggtctt gatattggat atttattagc tattacgttt
      601 gcatcagttg cttcaacatc atttattttt aagctattta ctttctcatc aacataacca
      661 aatgatatat atcctatcgc attttcgttt ccttcaactg tagtttttat attccctgaa
      721 ccatcactta tttgtgcatc tttagttaat tcttctgagt caaaacctac aatttcttgg
      781 aatccatctc tagttcctga accttcttct cttgatacta ttactattgg tgcatcattt
      841 cctcctactt ctttccaatt agttatcttt cctgtatata tacctttaac ttggtccatt
      901 gttagatttt ttattgggtt agcagtatta gttatcaatg ctataccatc tattgctatt
      961 ttagtttcct ttaatccagc acttttttct tcatctttta aatctcttga actcattcct
     1021 atttcagatg ttccttctat agcatttttt atacctccag aagaaccaat ttgttgtact
     1081 tctacactaa cacctttatt tttttcctga aacttttctc cgatagtttc cataagagga
     1141 cctattgaag ttgaacctga aacagaaact ttacttgaat ctcctgaatt tcctgaattt
     1201 cctgaacctc ctgagttaga accacaccct actgctaaag ctccaactaa aattgtacta
     1261 gctaaaagaa ctcctatttt ctttttaaac attttactta cccccgctta tattttaatt
     1321 ttttgttgtc atttttctat atcttaataa tacagatttt ttgttaaatg aatattagag
     1381 cagggttaag taaatgtaaa tattgttaaa tacatgtaaa aacttaattt tatataattt
     1441 attcctaatt agattaactt tttaaagtta gttttaaata gatataaaca taatacaact
     1501 catattatta taattcttca ttgaaactat caacctatta cattctataa ctctttttct
     1561 agtttattaa ctaattcagc aaacacattc aatgcttcct ctatagattc ttttttcgtc
     1621 atatctacac cagcagattt taattgttct agtggatatt ctgaccctcc actttttaag
     1681 aagtttatat atctatctac tgcagtactt ccttctgaaa gtatctgttg acttaaagca
     1741 cttgcagcag aaaatcctgt ggcatactta tatacataga agtttgaata aaaatgaggg
     1801 attctagccc attctattcc tatttgttta tctactattg cagattttcc gtaatacttt
     1861 tcgtttaatt tgtagtatat gtcagtaaat tcatcagcag taagtggttc tccattctct
     1921 actctttcat gtacaatttt ctcaaattca gcaaacatag tttgtctata aactgtagtt
     1981 ctaaattgtt ctaaataata atttaataag tatatagttt catccttaga tttagaattt
     2041 tctaataaat aatttataag aagtaattca tttaatgtag atgcaacctc tgcaacaaat
     2101 atcttatagt ctgaatataa aaacggttga cttgttcttg aataatgact gtgaacagag
     2161 tgccctaatt catgaattaa agtgaataga gaattaaggt catttttata gctcattaat
     2221 atataaggat gtgaatcata acttccccaa gaataagctc ctcctttttt accttcatta
     2281 tcatatacat caatccagcc ttcatcaaaa gcacttttta taaccttcaa gtattcttct
     2341 cctaaaggct taagtgcttc taatatgata tcttgtgctt tatcatatgg tatatccatg
     2401 tcaaatttat ctgtcaaagg aacatacaaa tcatacatgt gtatttcatt caatcctaaa
     2461 aatttctttt taagctcaac atatttattt agattaggaa tacttttatc tatagctgat
     2521 ataagattat tgtagacatc taaacttaca tcatctgaaa ataaagacgc ttctattgct
     2581 gaattatact ttctagtttt tgcgtaaaat atctctgatt ttattccacc ataaagagtt
     2641 gaggcaaatg tatttttata tttctcatat gttgaaaatt caccttcaaa agcgtctttt
     2701 ctaactctac tattcttact ttttataaat aaagaatagt ttgaatgaga aagcttgacc
     2761 ttattaccat cttcatcttc tatctcagga aattgcatat ctgcatatgc taacatatcg
     2821 tatacatttt ctggaactgt cgataattct gatgtagctg caagaatttc ttcttctcgt
     2881 tcactcaaag tatgtggttt atctctcaat atatccttta tatattttgt ataaaaagat
     2941 aacttatcat cttttaaata ttcacttaac ttattctctt ctatagccag tatttctgga
     3001 actatataag aagtagccac acccaaatca gtagataaca tttctgtctt agtagctctt
     3061 ccttgattat cattaattct agtatcttca tgttgtttca tatgagtata tacatataaa
     3121 ttttgaacaa tcctagatgc attttcagag atatttaata ctttatataa gttctcctta
     3181 ctatcagaaa gcttcccttt atattctttt acttcttgga taagattttt tactttgctt
     3241 atgtcttttt caatttcctc tttgttagag tacatcttat ctatcttcca tttatacttt
     3301 tcttctattg tacttctatc agttcccata tcatacacct ctattttaat ttgttttata
     3361 ttttattcac tttacaaaat atattgtata tattttagtc caaataatct acatttatta
     3421 ctccttctat catatttatt tctttcataa catcttgcaa gtgtattctc ttagcataag
     3481 atacaaaaaa attgaccttc cagtattctt cattacgaca ttctatttcc atatttctta
     3541 tgataagttg acttttttca aatttatcat ataaaaaagg tatagagtcc aaattgctta
     3601 attttaatat caatacattt ttttcttgac taaataaaaa tgtattgatt atcctaagca
     3661 caaataatgc tatcattaca aataatccac ctagaattgc caattcataa taaccatatc
     3721 caactgctac accaatacat gcagttgccc acataccagc agctgtagtg agacctttta
     3781 ctccaccttt attttttaaa attgctcctg cacctaaaaa accaattcca gataatactt
     3841 gagcaggcat tcttgctggg tcagcatttg tatacaaatt ataatcaaag aataattgaa
     3901 tcgaagttat tgaaacaata caagaaccta ttgcaattag tatatgtgtt ctaaatcctg
     3961 caaactgtct tattttttct ctctctaaac cgattattcc tccaattatt aatgctaata
     4021 gtaaccttaa tgctatctcc ttacttccta tatcaatcat aatataaaac cctcctgact
     4081 taattacaac ctatgtccta cagataattt acacatcaga aatactattt tatatcttaa
     4141 tattattatt aatatatgta aaatatagcc atctgttaat ttttgataca aaaaaaccca
     4201 caactgtggg ctatttgctt aggtacatgt atttatttat taatatatct attttcttac
     4261 ttgattctac taactcttct tgaaatattt ctggatattc tatgtatgta tttatctctt
     4321 ccctaactgc ttcaatctca ttttttaacg cttctaattc attgttcgcc ataataatca
     4381 ccactattac aaatttgtat atttttatat acattttatc aaacaatatt atattttgtc
     4441 aatattatgt caataaaact tactataaaa atgttttaat ttaggtattg tatacctgga
     4501 tactaaacct acaaacatac cagttactaa tgatgccatt aacataaatg gtaagtaccc
     4561 tatagcaagt atattttcta tgattaaact tgcaactatt aattgaccta tattatgccc
     4621 tattgcacct ataatgctta tccctattat tgataaacct tttattttgc tcgctaaata
     4681 cataaataaa agactcagat aagctcctcc tatactaaat agtagatatg ataaagggcc
     4741 tgcaaatatt gatgacaaaa ttaccctgat agtaacaatt ataacagtat ctttgacacc
     4801 taacaacatt aatgaaatta aagttataat attgctcaag cccaatttcg cccctggaaa
     4861 tataactata agaggatttg gtatatatgt ctctagtaca tataaagcta aactataccc
     4921 tatcataaga cctaaaaatg tcatttttct agttttcatt aagttaactc ctccaaattt
     4981 tatctatcat cttacattat aatacaaaat atataaaaac acctaattta gactaaaata
     5041 ttttttaatc tatttagaat aaatattagt tatttcaatg tgcaattacc tctataattc
     5101 ttgacttttt gtatcatact tgttacaatt ttaatgataa tgaatttcat taggaggtgt
     5161 taataatgac tgtttacgat ttaaaaatag gagaaaaagg atttattaat agtatagatg
     5221 gagatattaa attatctaaa agattacttg cacttggatg tataaatagt actgaaatag
     5281 aagttaaaaa ggttgcccca cttggagacc caattataat tagatttaga ggctttgacc
     5341 ttgcgattag aaaatctgat gctaaaaata tttctttaca ataatagagg aggagctacc
     5401 cgtgattaat gtagcattat taggaaaccc aaatgtcggt aaaactactg tttttaatct
     5461 acttacaggt tcaaatcaat atgtaggtaa ctggcctggt gttactatag aaaaaaaaga
     5521 aggatttctt ggaaaagaga taaaggttgt cgatttacct ggtatatatg caatggatac
     5581 tttctcaaat gaagaaaagg tttctaaatc atatttagaa aatgaagatg ttgatgtaat
     5641 agtaaatgta gttgatgctt ctaatttatc aagaaacctt tatttaacaa ctcaacttat
     5701 gcaatttaac aagcctatag ttatattgct taatatgtta gacattgcag aatctaaagg
     5761 agttaatata gatgctaaaa aattaggcga agaacttgga gtaattgttg ttccaattat
     5821 agcaaaaaag aaaaatggcg ttgataggat agaagaagag attaagggag ctacacaaaa
     5881 agcttttata tatcaaaaaa actttggaag tgaaacagaa acatataaaa aattagaatc
     5941 cattttatca agatgtacaa aaactacata tacacagaaa aaatctatca gtgataagat
     6001 agacaatata gccttgaatc ctatattagc atatccgata tttattggtg tattattcct
     6061 cttatttaaa tttacctttg attgggttgg aggaccgcta caagagggat ttgctagtct
     6121 tatagaggct tatatttctg cacctgttag tgatatgtta tctaactcta gcccatggtt
     6181 taaatcactt atagttgatg gaataattgg aggtgttggt ggtactttac cattcttccc
     6241 tttaatattt acattattct ttggtatatc gttgtttgaa gatagtggat acatgtcaag
     6301 aacagcattt ttaatggata aagtcatgag aaaagttggt ctatctggta aagcttttat
     6361 acctatagtt atgggtatgg gatgttcttc tccagctata atggcaacta gaacattgga
     6421 aagtgaaaaa gatagaagag ttacagctct tattgcacca cttatgactt gtggagcaaa
     6481 gctacctata tatgcactat ttgtagctat attctttcca cataatgctg ctttagtaac
     6541 tacgtcactg tacttagtag gtatagttat ggcaattgta gttgcattat tcttaaataa
     6601 aacagccttc aaaacagagg ctgaaccatt tatattagaa ttaccagaat atagaatccc
     6661 tactatagat gcacttatta aaaatacttg gaataaatca aaaggtttct tgataagagt
     6721 tgttactgtc atgtttgcaa tgtcagtcgt aatttgggga ctttcttcat tcaatgtttt
     6781 tggatataca gaggatataa atgtaagctt cttggctact ctaggtcata ttatatctcc
     6841 tatattcaaa cctcttggtt ttgatgattg gagaacttca gttgctattt taagtggtct
     6901 tggagcaaaa gaaatcgtcg taaactcttt aaatatacta tatggtaatc taactgttgt
     6961 cttaccaaca atatttaatg gagttactgc atatactttc ttgatattta ctgctttata
     7021 tactccatgt atagctgcac ttgcaactat gaaaaaagaa tatggcaata aaatgatgtt
     7081 tgcatcattt gcatatcaat ttatactagc atggataatg gcttttatag ttaaaagtat
     7141 aggtggagta ctatttatgg gcaattcaat agtggaagct ttgataggtg gaataattat
     7201 agcccttgca ctttttattt tgtttaataa gttcaagtct acaaaaaacg gaagtgtgtg
     7261 tagtggatgt tctatttgct ctggatgtcc aagtgctaat tcttgctcaa gtaaggaaga
     7321 cagtaataaa aaaaatagta cacactaata tataaatatt ttagtttaaa ataacgtaga
     7381 agtgagtgtc ttaaaattaa ctttttagtt cattaggcac tcttttttat atggaataaa
     7441 atatattttt atcatttcaa cagtcaaaaa gaggcttatc tatattttga gacagcctct
     7501 tattttttac ttattcaatt tcttgctacc taacttcata tggaacttag tatcttttgg
     7561 gatgcttggg tctattcccc ttaatgtagg tatttcccca catattagtt gtataggtac
     7621 tataaaatta aatgtttgat agtaaggatt atctgtaata tctattttta aatttttatc
     7681 attttctgta acatctctac ctatagcaaa tacattttcc gtccaaccag aaagtacatc
     7741 aatcatctta gttactctag gttcttttcc tgtatctagt ataaatatag tagaatcact
     7801 atttatagca ttatatatac catgtataaa ttcttcaaat tcatacccag ttacaggtat
     7861 tctcattgtt tccaataatt tcaatgctgc ttctaatgta tctccatata tatcagagtg
     7921 gcctattatt cttatttctt tagaattaac taactttttt ttgtttcttt caatccattg
     7981 tttagacaac ttatacactg cttcaaatct attaattgca tctaatatct tatttatttc
     8041 atcattgtac ttttcactag atattagtcc tttttctcta gctatttgaa gacctaacaa
     8101 cattaagttt aactttgtac aataatatcc ttttgtttta gctccagatt tttcttctcc
     8161 acaatttact gttaatatat aatcagaaat ctcatctatt agagcatttt tacaacccgc
     8221 catagatgct attttacacc ccttgtcttc agccaacttc atagcattgt atgtagaata
     8281 actactccca ccttgagata cacctactac tagggtattt tcattatcaa acttgaatgt
     8341 atcttcagtt atcataaatg gatacatttt cacaacatct atatctaata agttttgtaa
     8401 atatggttgc acttgcactc ctgagtgata gctagtacct gaaccagtta ttataatctt
     8461 ttttagattt tctttcttaa cttcattgaa taagctatct gcattagata taatttctct
     8521 cattctaact ggtgtttcta acatataatc ttgtattgtc attttatacg ccttccttat
     8581 ctatatattc aataaattac aattaacttc tataacaaac ctatagcatg taaaactatt
     8641 cctgctacta tagttcctat agttaatttt gttacactta cctttctctt taacatgtaa
     8701 tatattacaa atgcaaaggt taaaggtaac atattaggta ttattttatc tagtatatct
     8761 tgtaaaatta cttctgcacc atttaagtta aatttcagag gagtagttat actcaacata
     8821 gttgcaacca ttcctcctac aacaaataaa ccgacagttg tagccataga cattatttta
     8881 tccataagtc cttctctttg tattctatca agagaattta ctcctacttg ataaccatac
     8941 ttaagtccaa atattctaag agcaagtgct ggtatattat ataatagtaa gaataatagt
     9001 ggtccaaaga tattaccttc ttttgaaagt gatactccta ctcctgctgc tataatccta
     9061 aatgttcccc agaatagtga atcaccaatt cctgcaagag gtcccataag agctgtttta
     9121 acagcactaa ttgaactttc atcaaattct ggattattag cattctcttc ttccatagct
     9181 gctgttatac ctaatatagc aggaactacc actgtcgttg tattaaaaat ctccaagtgt
     9241 ctttctattg cttttgcttg attttctttc ttattgtata acttctttat tgcaggtaac
     9301 attgaataac agtaacctaa gttttgcatt ctttcgtaat taaatgcacc ctgaagagca
     9361 aatgaacgcc aaaacatact tcttaattct ttttttgtta atttattcaa agtcaatctc
     9421 tccttctatc aaagtattaa ttgctaattg aggattttga ttattttctt tgttattgat
     9481 ataaaaattt agtacaaatg ctacacatac tccaaataaa gctatagcag ttatatccaa
     9541 tccaccataa gatgctaata aaaaccctat aaagaaaaac acagacattt tttttgaaaa
     9601 taacatatcc ataagcaatg caaaacctac tgctggtaac aatgttcctg caacacccaa
     9661 accgtctaat ataattttag gtattgcatt tatcaatgct gtaactttat cagcaccaat
     9721 cataattgct aaaaaagttg gaactgatgt acttaaaaag aataatatta ctggcaacca
     9781 catcattatg gtaactctct taaaatcagc ctgtttagca tagaaaactg ccctttgaga
     9841 aaaatacgaa tttattattc taaccagtac tccaagagat tgtgctaaga ctgctactgg
     9901 cactgctact gctaaagcaa cttctgcacc attacctgat aatatagcaa aagctgtacc
     9961 taatacacct cctgttacta cgtctggagg agtagctgca cctattcctg taattcccat
    10021 ccaaattaat tcaagctgtg caccaatcat aattcctgat tttatatctc ctaaaactaa
    10081 tcctactaac atacctgtaa ctatcggcct atcaaacata gattgaccaa atatacgccc
    10141 atctaatata ccaactcctg ctataatagc taacatagta gcttgtacta acatagttaa
    10201 cctccatttt aacttagttt aatttacatt aaattatatt tttgattttg ttttgatttt
    10261 ctaataactc atttacataa acaattccat tttttgcttc ctctaagcct gatttaatta
    10321 ttagttttgt atcctcttca actaataaaa gtatagataa aagcattggt aaatttactc
    10381 ctgtcaataa ttcaaatttg aacccttgta aaagtaagtt tgtacatatg tttgccacac
    10441 ttccaccaaa cacatctgtt aatacaacaa acgcttcact atctttatta tttaataata
    10501 tacttctaat ttctttttca gcatcatctg ctgatttatc ctttgtcata caaaaatact
    10561 caatattagt taatgaacca attatcaatt tacttgtatc aacaagttct ctagacaatt
    10621 ctccatgtgt cgcaattaga aattttttca ttctctttct cctaaattat tttattaaat
    10681 ttgatagttg tttcttttta tctctaggta acattctaaa ttctatatca attcctaaat
    10741 cacttatttc tttaaagtta tttatatcat cattatcaac agcaactaaa tctgtaagtt
    10801 tcttctttcc ttcttcatat cttaaccctc ctacatttat ttcttttaat actcctcctg
    10861 agtttttagc tataactaaa gcatctttgg tattttttac taacactaat acattgcttt
    10921 tctttgaaga agcaaatttt tctactattt ctccagactc ctctaccccc cttatatata
    10981 aagttacatt gctaggttta gctaaattca gtgacatagc tttcatttgg tcattttttg
    11041 cttcatcatt tgcaactagt attacattta tccctagtga tgttgcccat ccatatgcca
    11101 cctgaccatg tatcaatctg tcatcaattc tcattaaaga taccattttc ctcaaatcct
    11161 ccatcataca ttaaaatttt tattgtttgt cctctaattt atctataaaa gcaaaaagta
    11221 tgccaaatac tggcatactt tttcgaattt cattcactta ttttgtaatc ttgtatttta
    11281 ctgtggtaga ccatagatga tattataaat gtatcctatc tctgaaattg atatttgcac
    11341 actataactc ttttctagca cactaaatgc attttttatt aattttactt cactatgatg
    11401 gtttttgatt aacaaatcca tatcagtata ctcttcaatt tcagcttgtc taactaatct
    11461 ttcaatcatg caacttaagt gaacatataa agcaattttt ttatcatttg gaagtttttt
    11521 cttttgaata ttttctatag cgttgattcc ctcttctatt ctctctatta tcttctttga
    11581 atctaaaata gttagactgt ctattactct aattaatgaa aaattcttta caatagaatc
    11641 atttatgctc tttatttttt cattttctac tactccacta aatattctaa aaacatcatc
    11701 ttctcctttt cctgatatta tatcctctaa taatataaaa tccaccccat tcacatttgg
    11761 attggcagtt cctactatag ccagtacatc atacatttca aaaactggtt ctttatctcc
    11821 catagaaaca agactatcat aatcataagg tattattttg acatcaacta ttccaattaa
    11881 actttctgaa agtaggtgtt ggatttttat agcagtacct atccctgtaa agcaagatga
    11941 tattatagca tattctttat ttttttgagg ataatacaat tgtatattag gtttagtctc
    12001 ttcatccata atttctgcaa tctcttcaat gttcttacct tgcattaata aatttcctac
    12061 ttctagtgca gaaatggtgg atatttggtc tataaataac attgtgctat ttatcttact
    12121 ctttaaatct tcgtatataa gattaagaga gcccatatca aataacacaa ttaaaccatt
    12181 ctttatccta tctccctcta ggtatctaga catttgtttt gatacatcag caatggtagc
    12241 atctataggc atatcaatag cagtgaatat atttttaccc aacattcgat tacatacatt
    12301 cgccatacta ctggcagtag cataaccatg tgctataata atcgcattaa cctgattaaa
    12361 tttcattctt ataattgtcg acttaataaa tataatcatt atgattgtat ctacattatt
    12421 aagatacata tccaatctat tcattattaa tgttgatatt ttacttatta tagagtattc
    12481 tttgtaactc tcttttttta aatatattag caatttattt tctaaagctt tatattcatc
    12541 agacaattga tacgattcat ctttcaaata aagataagac gaaaatgcca atacattatt
    12601 cccatcatat tttatattgt tattaacttc taaatttcta aatatatcct gcattattga
    12661 tattataagc tccataagta cgttattatt ttcatcatta tttgaaaaaa ctaaattatc
    12721 cattaatcta gtcactagat tagaactctt tttactaaat ctttcttttg ttatttcatt
    12781 tttttgtagt ctatcaaagt aatctaaaca ttttataaaa ctttgatata ttatgcttct
    12841 tttatttgtt ccatttgaca tttcaatact aaattgttta ggtgaaaaga caatgctttt
    12901 gcttttacca ctttgaaatt gaaatatgtc tacattttct atataaagat ttctaggaag
    12961 gtcttgaaga gtaacgaaaa tatttccatt tcttctttga ttttttgcat aagctcgtcc
    13021 acatgcatat tttattacat ttttacattc gcctatattc cccttgaatt ttatctttaa
    13081 aatcgtattt aatgtaattt gagttatctc tataggcaaa ccaagtacct tactttcctc
    13141 ataaataaaa tgttctacaa tctttctttt ttcaatactc cctctttctt ctatattagg
    13201 aatataaata tttatgggta ttcttcttaa aaaagtttgt aaaaactcag ataggctctc
    13261 tgttgtagca aatattaatc ttaccctagc ttttctaatt actccattct ctccaattct
    13321 ggaaaacgta cctgtatcca taaatgtaaa taacttttcc tgaccttcac tatttaatct
    13381 atgtacttca tctaaaaata aaacaccgcc atcagactgt tctattagac ctgctctaga
    13441 ttcatttgcc ccagtatatg ctccttttac atgcccaaat aatagactag acaataactc
    13501 caaattatta taatactgcg cacagtttaa cacattgtat ggagaatttt tttctaatac
    13561 attactactt acactatatt tatatattat cttggctaaa aaagtttttc ctactccact
    13621 ttcacctgtc agcattatcg taagcccacc atttggataa agcacagcag tttttatttg
    13681 ttcgattacc tcttttaagc tattatcgta tcctatgata ctattaaaca caatctcttg
    13741 ctttaataat ttgcactcat ttttaagttc atctaaactt tcataaatac ttttttttgt
    13801 aggtcctact acatcattta tcttactttt aggtaaaaaa ataacaggtc tactatttat
    13861 ctttataaga ttatcagatt ttactaagtc atttaataat ctacttgatt gagttctact
    13921 taaattaaac ttttttacta tgtcttctgt cactatgcca ctttcttttt taagttcatc
    13981 aaagttgtta aataatgcac attcatttac aaaacttaaa atttcatccc tcatgttcaa
    14041 cctccaatac aaatatcaat aataatataa tattagtata tcatttatat atttatgaaa
    14101 aagataatta tattcctatc ttaattctct tttgtaagat tgtaaaatca aactttttat
    14161 aagtataaaa tctagatttt ttaacataat ctcaagattc ttatcttcct atatatttga
    14221 tacagagttt atataataat atatttattg tatttagtat aataaaaagt aaaacattat
    14281 aggtatttta aaacgtatta gtgaagaaaa tatttgtaac ctttattata ttatgaatat
    14341 tatttcagat ttaaaaaggc tataaataaa tttattttta aataaatcta cttatagcct
    14401 cacaataata cttataaatt ttatttttcc acaataatgt atctcaaata tagttaaaaa
    14461 tatatctatt taattattaa tatttaagta ataaagtctc actcaatcat taaattcctt
    14521 tttatagcaa attactctta tttcacttat gcttaataca tttatagata taaatactaa
    14581 aaaagcaatt caataaacca tatgataaac ctaatttatg tctgttattt gctcatatct
    14641 ttagacttat ctatacaagc aacaatagat tttataactg ccgctctaaa tccttcttct
    14701 tctaatacct taacagcttc tatagtagtt cctgctggag aacaaaccat atcttttaac
    14761 tcacctggat gttttccagt ttcaagaacc atcttagctg accccattac tgcttgagat
    14821 gcaaatttat aagcttgttg tcttggcatt ccagctaata ctgctgcatc tgccatagcc
    14881 tctataaaca taaatacata tgcaggagaa gagccactaa tacctgtaac tgtatccatt
    14941 aaatattctg atactatctc tgcctcacca aaagattcaa acatagcctt aatcatattt
    15001 aactcttcat ctgttacatt actattttta caaagagctg acattccttc cccaacaagg
    15061 gctggagtat taggcattac tcttactatt tttttatctg agcctataaa actttccaga
    15121 ctttctatag ttttacctgc tgctatagat actattattt tatttgcatc tattaattct
    15181 ttaagtggag ttaaagcctt ttcgcatata ttaggtttaa gtgctactat taccacatca
    15241 gaatttgcaa cagctacctt tgagtcagtt gtagtattta ctccaaattc ttcttttact
    15301 ttatctaagg caacttggct taagtctgat acagttatgt cttttgcttt tactaatcct
    15361 gactgtacta taccacctat cattgcactt cccatattac ctgaaccaat aaatcctaaa
    15421 gttttcatat caaatctcct tttttctatt agttttattt taaagtagct aaattaactt
    15481 tattttaact gcttaaaatt atcttatttt tataaaatat aaccttatta taattataac
    15541 aaattacttt tttgtatgta ttacttacta atatatgtat gatttattaa atataaattt
    15601 aacgattttt tcattaaact taacgagcta acttcctgtt tagaaagtta gctcataatt
    15661 aatctaaaat ttttaaaata taatcaaacc atttatactt tattatatca gttacgattt
    15721 tatatagtaa gaagttttat ttgcaagcaa tcctagaatg tttgctcagt tcttcctatt
    15781 atctcatctt gtagtgttct acttaaatta ttgaaatggt cactatatcc tgcaactcta
    15841 actattaaat ctttataatc ctgaggattt ttttgagcct ctaacagtac atttttatca
    15901 aatacattaa attgtatatg atgaccatcc atattaaagt atgctctcac tagattagcc
    15961 atattgtcta accctttttc tccttgaact actgatgggg caaatctttg atttaatagt
    16021 gttccaccag tttttatgtg gtccatctta gcacaagatt ttataactgc tgtaggcccg
    16081 ttagtatctc cacctttttc aggtgaaatt ccctctgaaa ctggttttgc acaaagtcta
    16141 ccatttggac ttgctcccat aatttctcca aagtatatat gacaagttgt tggtaacata
    16201 tctactctgt attctccacc acaaacagtt ggtctaccag ttacctcatt gtaatatgca
    16261 ttgaatatct cttgcattat ctcatcagca taatcatcat catttccata tttaggagtc
    16321 ttatttgaaa ctaaattaag tatagcttcg tatccttcaa aattagcatc aagtgcttta
    16381 agtaatgtgt ccatatcaaa ttttttctta tcaaatacat tatattttat tgctgtcaaa
    16441 ctatctgtta tagttcctat accaacacct tgtatatatc tagtgttgta tcttgctcca
    16501 cctctttggt aatccttgcc tttttctata caatcatcaa ctattgtaga cataagtgga
    16561 caaggcatgt gttttgcaca tatattttct atcacagcat ttccttctat ttttatgtca
    16621 atcatataat gtaattgctt tttaaatgct tcaaatagtt cctcataaga tttgaaattt
    16681 ctagggtctc cagtttcaat acctatttgt tttttactaa ttgggtcata tccattattt
    16741 aatgttaatt caagtatttt tggaatgttc atatatccag ttaaaacata tgcttcttta
    16801 ccaaaacatc cagtttcaac acaaccacta gttccaccaa gtcttgcatc ttctatagtt
    16861 tttccagctt ccataagctc ttgaactatt gcttcagtat tataaaatgc tggttgaccc
    16921 catccttttc ttgatatttc acaagctctc tttaggaatt tttgaggagt ctttttactt
    16981 atttgaacat ttgaactagg ttgtatcaat ttcatttcat ccataacatc aagtattata
    17041 taactaactt cattaacacc atcttgacca tctggattta ttccaccagt gtttatattt
    17101 gcaaaatctg tatatgtgct actttctttt aatgttatac caacttttgg tggtgctggt
    17161 tgattgttaa atttaaccca taaacattca agtaattctt gtgctctatc tctatctagt
    17221 attccatttt ctacatctct ttcatagaaa ggatttagat gctggtcaag tcttcctgga
    17281 gtaaaagcat cccatatatt aagttcagta gtaaccccta tatgaacaaa ccaatacatt
    17341 tgtatagctt gatgataagt ttctggtttg tgagctggta caacatcaca agtttcagca
    17401 attagtaata aatctttttt cttagcttca tctgtttctt cttctgccat ttgtcttgct
    17461 ttctcagcat atcttttacc taatataacc attgcatcac aagctattgc catagcttct
    17521 aaatcagctt ttttattata tgcatctaaa tcattaagaa aatctagctc ttttaatctt
    17581 gcttctatat ctttctttaa atctaaaaat ccttttttgt atattgtatc tccacaaact
    17641 gtatgtcctg gagctctttg ctccataaac tctgtaaaca tacctgcttc atatgctgct
    17701 aaccactcag gtgtcattgc atttattatc ttatctcttg tttgtctctt tttccaaaaa
    17761 ggaattattt cttctttatg tatttttcta gcttcttcag atacgctaaa atttattata
    17821 tctctattgt gcattacttc taaatcttcc attgtatgac aacaaatttc tggatatgtt
    17881 ggtgctccat taggagaatc acctttttca cctactatta attctccatc atttatgcta
    17941 agagttctat tctcaatata atgcttaaat gataaagcac gaagtacagg aatctctaca
    18001 cttccctcat attttttata agcttctgtc ataagtactg ctctttcaat agatatgtgt
    18061 ggttctgcat taatactttc ttctcttaat tttttagttc tctcaaaagt tcctcttgcc
    18121 attttattac cctccaatct cagtattgaa attacttgct tcaaaaagtc tttttatttc
    18181 ctctaatttt tcttctgatg gtctttgtag ttcttctcct tcatactttt tataaatctt
    18241 atcatactta tgtttaccaa tattatgata tggaagaaga ctcactgctt gtatattcaa
    18301 aggttttaaa aactctatca tttttttaac ctctaaattt tcatcatcta catttactcc
    18361 tacaattaat ggtattctta tatttatgtt agcccctaat tcacttaaaa ccttaacatt
    18421 tttcagtatt aagtcatttg attttcctgt aaattttatg tgcttctctt catcaataag
    18481 cttaatatca tataaaaaca aatctgcata tttagcaact ctttcataat tttctgactt
    18541 tgcatagcca catgtatcaa ttgctacatg gattcccttt gatttgcaca tatttattac
    18601 tccacaaatg aagtccatat cttgagccat tacttctcca cctgacagag ttactccacc
    18661 acctgattct tcatagaaaa ttctatcctt gtctatctct ttaaccaagt ctcttacaga
    18721 atactcttga ccaacaatct cccttgcatt gtttacacaa tagtctaagc aagtttcaca
    18781 aaattcacac ttatcttggt ctaggcatat ttttgtttca cctttgtaaa ttgccttatg
    18841 agggcatata tttatacatg cttcacatct tgaacatctt tcttcattat acaaaacttg
    18901 ttttgtatat gtttgactct ctggattatg acaccaaaca cattcaagtg gacacccttt
    18961 aaaaaatact gtgcttctta tccctggtcc atcatgtatg ctgcattttt gtaagtttat
    19021 aactaatgga ttcataattt ttcaccccta aataatatcc attccatttt ttcattttta
    19081 tgtaatttat cttcatagaa tatacctatg aaaagcattt ctacaattac ataatactat
    19141 acttgttatt attttgtcta tatcttttta gtaatattaa aaaattttat tttattatga
    19201 tatttatatt gtttttgtaa attaaattta aatatttatt aaatttattt ttataagaaa
    19261 atatagcaat aagccataaa caatacatca ttttaattaa tttagatgta tatactataa
    19321 aaattaaata aaaatagaga ctacacttta ccatgtagtc tctatttttc tggtcatatt
    19381 tagaaattta catttattgt tactgctttt ccacctctat ttactgttat ttttgtacta
    19441 gctccttttg ataaggtata caacttttta tttaaatcat tcatacctgt tatgtctgtg
    19501 tctcctactt tagttataat atctcctacc tttacaccag ctttttctgc tgatgaacca
    19561 gatattactt cagcaacata aacaccttta tcagtactta attttgtacc tgttgctgct
    19621 tcataatttg atacatctgt accttttata cctaaagtta ctttttcata ttttccagtt
    19681 tttattactt cttcaactat actcttagct gtattgattg gaattgcaaa tcctaatcct
    19741 tctgctttag aagcttttgc tgtatttata ccaattactt gacctttttg atttaataat
    19801 ggccctccac tatttcctgc atttatactt gcatcagttt gtaacaaacc agtcatagta
    19861 gttttttctg tttgtatagt tctatctaaa ccacttatta taccttgagt aactgttttt
    19921 tggaaatcca acccaagagg attacctatt gctattgaaa tatctccaac ttttacttta
    19981 tcactatcag caaattctgc tggtgttagc ccagttttat caaccttaac tatagctaaa
    20041 tcaagttgtt ggtcaaacca tactacttta cctgaagttg ttgaaccatc attgaataat
    20101 acatttacac ttgtagcttg accatctgat ataacatgag aattagtaag tatatatcca
    20161 tttgaatcaa ctatgattcc agttcctaca ccctgtgttt cagttggtat tgcaaacata
    20221 ttattagtat caacactagt tgttgtaata cctacaacag atggtgtagc tttttctgca
    20281 actgcttgat aaatattttg actcttacca tcatcattta caattattgg tgtagaactt
    20341 cctgtagatt tgcctactaa attatcctta actaaaatta ttgttagaaa actactaagt
    20401 attgaactta ttatagcaac taatattact aaacttatcc ctttctttct tcttgacatc
    20461 tcataccact ccctatctaa tataatataa attatcaaaa tatatttttc ccaatttttc
    20521 ataaaaaaaa tgaaatcatc tattttgagt aaactccttt tcgatgattt cattatatta
    20581 ttttaatctt aattaaacct taactattta aaattattta agtctttttt ctagctcttc
    20641 cttttctttt tcataacctg gttttcctag taaagcaaac atgtttttct tgtaagcttc
    20701 tactcccggt tggtcaaatg gattaactcc caataaatat ccacttattc cacaagcctt
    20761 ttcaaagaaa tacactaagt atccaaaatt atactcatct aattgaggta tatttattac
    20821 taaattaggt acttttccat ctgtatgagc caatagagtt ccttcaaaag ctttatgatt
    20881 tacaaaatct acagtcttcc ctgctagata atttaaacca tctaagtcta cttcctctga
    20941 atttatagtt atatttctct tacaattttc aacattaagt actgtctcaa ataaaagtct
    21001 ttttccatct tgtatgtatt gacccataga atgtaaatct gttgagaaat ctacagaagc
    21061 agggaataaa cctttatttt cttttccttc actttctcca taaagctgtt tccaccactc
    21121 acttacatag tgtagttgag gttcatagtt aaccaataac tctacatctt ttccttttct
    21181 atgtaaaatt gttctagcaa cagcatatct ataactatca ttatttttta ggtcaggatt
    21241 ttgaaatgct tctctagcat catttgcacc tttcatcata gcatcaatat caagaccagc
    21301 agcagcaata ggaagtaatc caactgctgt caatacagaa aaacgaccac ctacatcatc
    21361 tggtattaca aaagtctcat atccttcttc tgtagctaac tgtctaagtg cacctttact
    21421 tgaatctgtt gttgcataaa ttctctttct tgcttcttcc ttaccatact ttttctctaa
    21481 gtaatcttta aatattctaa aagctagggc tggttctgta gtagttcctg atttagatat
    21541 tacatttaca gaaatatcct tcccttcaat tatatctaat aaatccataa tatatgttga
    21601 gcttatatta tgccctacaa aatatacttc tggagcattt ctttgctctt ttttaagtct
    21661 attcctaaaa gaatgactta ccatatctat agcagctctc gaacctaaat aagagcctcc
    21721 tatacctatt accaaaagaa aatctgagtc tgattttatc ttctcagcag atttttttat
    21781 tctgtcaaac tcttctttat cataattctt aggaaggtct atccatccta aaaaagtatt
    21841 tcctaaacca gttttattat gtaacatgtc gtgtgcaaca tctacatatg gttgcataac
    21901 atctatttcg ttttgacaaa aaaactctgt agctttacta taatcaaaat ttatttttct
    21961 catttaaatc cctcttttca gcatattcgt tttaaagaga ttataacaca aaatatgggc
    22021 gtttttttta aaagtttatc acaaaatcat acatatctca tcatttatta tcaggaaatc
    22081 gattcttcta aatgctataa ccatgtacaa ttttttaaat tttagtcaaa taaatttgca
    22141 aaaaaagaaa ctctaaacgt atcatttaaa gtttcttttt atttatattc tatttcaatt
    22201 tttatattgt tctaaactaa ctaactttaa tcattaccta atctcttcgc tataacttgt
    22261 tgtgctatat tgacagcatg gtcagatatt ctctctagat tacttattac atctaaataa
    22321 ataactccat tttctatact acatagatta ttgttcaatc tatacatatg attagctcta
    22381 caagatttct ccattatatc aacctgctct tcaattttta taaccttgca ggctaaatct
    22441 acattatcag ttctcattga ttctaatgca taagtatatg ctgaaacaac tctattatac
    22501 ataacatcaa gttcagactg tccttcttct gagaaagaaa tatttgaatc tatcgcaact
    22561 tgtgataatt cagctatatt tttagcgtgg tcaccaattc tttctatatc gttgactgta
    22621 ttaaacaagg tatccacaac ttctcttgaa tcatcatcta aaggtgcttt tgaaagttta
    22681 agtaagtaat tcaaaatagc tttctgtaaa tcattgatta atctctctct tctatatgtc
    22741 ttgtctattt tttcggttga atgttctact aaagcttcca tagatgcatt taaactttcc
    22801 ttagcctttt cacccatacg aagtgcttct tttatcgtat ttgcaagagc tatagaagga
    22861 gtttctatca ttctatcgtc tatatatttg atagtcttag tttcatcttc atctatgtca
    22921 cctgctctat caggaacaag ttttatagct agttttatga taaaatttgt aaatggtaaa
    22981 agtatcaata cagatattat attaaataat gtatgtgtat tggctatttg tcttgcaaca
    23041 ttgcttgggt cccagcttgt aaccatgctt actattggtt tattcaagaa tattaagaat
    23101 atcactgttc ctaaaacatt gaagattaga tgcatcatag ctgctcttcg tgcatttttg
    23161 ttggcaccaa tactcgataa cagtgaagtt acacatgtac caatattttg accataaaga
    23221 attggtagtg ctgctgataa tggcactaga ccttctgctg ccaatgcaac caacataccc
    23281 atagatgcac ttgaactttg tattattgct gtaatcccaa atcccaataa taatccaagt
    23341 attggatatc taccaaatgt aacaagtaag tcagtaaatc cttgatagtc tctcagtggc
    23401 tctactgcca tcttcataaa atccatacct gtaaataata taccaaaacc tataagtatt
    23461 tcggctatat tttttattct aggattattt ccaaataaat aaagtataat acctacacct
    23521 aatgctattg gagccatacc agttaagtca aaagatacca attgggctgt aacagtagtc
    23581 cctatattag cacccattat aactcctatt gcctgtttta aggtcattat tcctgcattt
    23641 acgaaaccaa caaccattac agtagtagca cttgaacttt gtattactgc tgtaactcct
    23701 gtacctacca aaactcccat aaataggtta ctagtaagta gttttattat cttttttagc
    23761 tttgtcccag cagatttttg aagaccttct cccataaggt tcataccata taagaacaga
    23821 cctaatccac ccattagact tattataatg ttcaaattat ttcctccttg taaagagatt
    23881 actgtatcta aaattttata acctattgta ttttatcaaa ttataggagt gataatgtta
    23941 aattcatgtt aaatattaaa aaatcattaa gtttatgtta aatttttgta ttattggtgt
    24001 atttttgtat tattttttct gcacatttta tgccatcaac tgctgctgtg actataccac
    24061 ctgcatatcc agcgccttct ccacatggat atagattcct aacactcact gattctaaag
    24121 tattttcatc tcttactatt cttattggtg atgatgacct agtttctacg cctgtcaaaa
    24181 cagcatcata cattgcaaac ccattcaatt ttttatcaag agatataaat gcttctctca
    24241 tagtctctgt tacaaaacta ggcaaacatt cacttaaatt tgtaagtgta tatccaggtc
    24301 tatatgatgg ttcaacattt cctaaattta aagaagtctt attatttata aaatctccaa
    24361 caagctgaac tggtgcattg taattttttc cacctaattc aaaagccaat ttttcatact
    24421 tctgctggaa atgtactcct gctagtggat tatcactctt aaaatcttct ggtgttacat
    24481 ttactaaaaa tgcactatta gcatttattt tatctcttgc atgttcactc ataccgtttg
    24541 taactatttc aaaatcattt gatgtagatg ctatgacgct acctcctgga cacatacaaa
    24601 aagtatatgc tgttcttcca tttgaaacat gctctataag tctataatcc gcagctccta
    24661 atctaggatg attgtaaaag tctttgtact gtgctttatt tattaaatct tgtggatgtt
    24721 caactctagc tcctattgca aaaggttttt gaactatttt tacgcctctt gaatataaca
    24781 tttcataagt atctcttgca ctatgcccaa cagctaatat aattgtatct gtatctattt
    24841 tttcagtatc atttattact acagattgta tagaatcatt tgatacaact atatctgtta
    24901 cttttgaatt aaacctaact tgaccaccta aacttattat ttcatttctt atatttttaa
    24961 ctacattttt taatatatct gttccaacat gtggcttatg tgagtataat atttcatctg
    25021 gtgctccaaa ttgaactaac tcttctaata cttttctaca tcttatatct tttattctag
    25081 ttgtaagttt accatccgaa aaagttcctg ctccaccttc tccaaattga acatttgaat
    25141 tattttttaa ttttctagta gtccaaaaat cacttatatc tttggttctg ctgtctacat
    25201 caagacctct ttcaagtatg attggttcat aacccatttg ggctaaaagc agacctgcaa
    25261 ataaaccagc tggtccacta ccaattacca aaggattatt ctttaatttt ttatcaccca
    25321 taggtacatt tatatatctg atttccttta tttttgttac atcttttatt tttgatttaa
    25381 gtattttatt ttcatcttta acttctacat ctacagaata aacaaattcc atttttcctt
    25441 tttttctagc atctatagat tctttatata tactatattt gattaagttt ttttctttta
    25501 ttcttagctt cttaagtaca atatctttta ataaagatat atctttatca attccaagtt
    25561 ttacattaga tattcttaac atattgtttt cctctcttag attgtaatat aaaaaagcta
    25621 gggttactcc tagctttcta caaatataac ttctatattc tcttttacta gattttctac
    25681 ccaaatctca tctagcacaa aattctttat tttgtttaca acaagtgttt tatctaaatc
    25741 ttttttcaag ttttttacta agaccattgc ttcaaccgat ttatgcaatc tttcaacata
    25801 cagagaatta actttaatca atacaaccct taattcacac acatataact tttcattacc
    25861 taaggtgatt tcatcatcat attcgtatac actaaattca tatgtatttt cataaggtgt
    25921 tatattttct attcctatat aatccattta tttatccttt tttagttata agacctctta
    25981 taaccttcat gttattaaac accttttcta agaagttctc tgcttcttca ttgtctaaaa
    26041 ggtttatttc aaggttttcg ttttctacaa tacctttaga tttacagtac tctttagcaa
    26101 tatttattag ttcatttttt ttatccatag ataaatcaaa ctctttatag tctattatta
    26161 tatattgttt ggtatcaggt gatacaccat tattatatcc tatttctata tgataaataa
    26221 ctgcatatat ttcttctccg ttgtacacag gtacagctgg gttagatttt ataaagttcg
    26281 ttgatacagc aattgcgttt cctaaactaa gactcattat taatacctct ttctaaacat
    26341 tatacatata ttatactata gattctttat ctatgactta aagcttttta taattaatta
    26401 agatattttt aaatctttgt atctttttcc tagcgtacta gagcttatat cgtatttctt
    26461 tgatatttga acttgagtta taggttgtcc tgcttctttc ttaacataat attcaacagc
    26521 agctgcccaa ccattttcag ctccttttat attctcatga ttttttttat attcattcca
    26581 aaactctata catgcatcta tattttcttt ttcaacattt tctttaagag tatctaaaac
    26641 tttacattcc tcttcagcta attcattttc tgaattaact tttgtatcgt ttttatctct
    26701 ctctttcttt aagtattcag ctatacttgg gtctaaaagc tgttgtatat acttgtatag
    26761 tatatgtgta tgataaatta agaatgactt catatctttg tatacatctt gatattgatt
    26821 gaatagattc ataatatcct ttaaaattat atctttaacc tcatttgata tacttatagt
    26881 tatatcaatc aatatgttag ttccctcaat atcaactatt ctagctatca tacaacttcc
    26941 gattttaaaa cttcttagaa gttttacatc ttctgtacaa agttcatttc cacttaaaca
    27001 gtcctttaat actatttttc cagcagaaat ttcttttact tcataaatac ttacgtatga
    27061 ttcaaacaga ctttttagta ttgatacttc tgactgactt aagtttgcac cattttcttc
    27121 aagaaagcca actgtcataa cctttttatt ttccattatg tggtcttgta ttaagtaagt
    27181 attaaaaaat ctttcaaatt tttcatttac actatcattt tgcattatat aaaacatttc
    27241 tttagctttt tcacattctt ctttaaactt atcctgtctt gaataatcat ataactttga
    27301 atataaatct gtatattgtt tttgtgaaag ttcagttttt ctgcatgctc tttctgaaac
    27361 aatatcttta tttaaacaac atttcttgta ttttttgcca cttccacaag ggcatagctc
    27421 atttctccct aacaatatga cttccactcc cttattatta aattaaagta caatttgtta
    27481 ttataccatt tttttattaa tcaatctata gtataagtaa atattctatt aaattcactt
    27541 atattttggt acaatatatt aactttaatt aggatttcga taaaatcatc aacaatccct
    27601 cttgtagaaa tgaattatcg taaaactaat tcctctataa aattttatta attgataata
    27661 gttttttact ttatctattc ttttttgtta tgtgactcta actgtcattt tacattcaac
    27721 aatattgtct ttttcttgtt tatattcact gagaatattt tgagcatcaa aattatttac
    27781 ttttaatttg ttaatttcta tcttttcaag tttattattt agccttaatt tcttcattac
    27841 atcttcaaat ttcaacacat tttcaagttc tccattaacc tttatttcta aattaacttg
    27901 ttttttgtta tgattatcta aactactttc ttgattaata tattctatgt tcacaatatt
    27961 tttcaattca ttttctacca ataacactat atctttattt gtttttttat ctaaaaatga
    28021 gttattaaaa ttatttttta attcttcatt ttcatttaat tcaacacttt ctatatattt
    28081 atcatctata tgcttattac cctttatttg ataattatct tgattattta ttttatttat
    28141 tatattttgc ttctcattct tcaaactagt taagttttct tccaagtaat ttaccactat
    28201 atcacttgcc accataataa ctaatattaa tagtatttta agtagatttt tttctctatt
    28261 atttaatctc aaaaataatc acccatctaa ctttttattc taaatctata atattctcca
    28321 tctcttacaa tactatctat gtaataatat tttatgtact ttattttcct taaattgtct
    28381 aaaacatcta aatcactaca cacaccttct atctctaatt tatttttatc tatccatatt
    28441 ctagtaatac tatttattcc aattgtttca tatatttttt ttatttcatt aagttttatt
    28501 ttagaaaatt tttctctagt tttatctgtt gttgatatag tgtgctttga tttatcaact
    28561 aacttatttt gacttatata atcttcaagt tcatttatag atttcacata cataaatgat
    28621 ttaaataaaa tacatgttaa aattaagact attattattt tatagacttt attacatgat
    28681 ttagtttttt tgaatccatt aagaaaattt attgttttat ctactttcac ttaaataatc
    28741 attcctatgc tacttatata atttatacta ttgtcttcta aatctgtatc aaaattattt
    28801 tctactttta ctttatcttt taatcttaat ggatttactt caatagattt atctgtatat
    28861 ttaaagtatt cttcaataaa acaattttct ataccatagt aataaatata cttgaagtcc
    28921 cttaataatc tttttataaa ctcatatgat tttctctctt ttgatagcaa gtatgtttct
    28981 tctatttttt tatcttttgt tatatttata atcaactgac tttttttaca ttctataaat
    29041 actccttctt ctgaaaagtt ctctattaaa tttaagttta taagcttttg taatatatca
    29101 aaatttatat ttatagtctt tggattcata tttagatttt ctgaaatgtt cttaattaat
    29161 tgaataatac tctttggaaa aagaattact tgtatattca atttatcatt tatagaattt
    29221 ataactttat attttattga atagttactt atgtttattg gaatgtattg tgttatttca
    29281 aattcaatca tgcttaatat atctcttttt ttcttagtat ctagaacttc aacatttcta
    29341 atgactatat cttgaatttg aatgttaaag tataaatttt tatatgatat ttttgattta
    29401 tcaatctcct cttttacaaa tctaactaca tcttctatat atttaatctt ctcaatcgaa
    29461 ttactatcat tttttatatt aaagttaatc tcttttataa ttgatttatc tataaaaact
    29521 tttttatgac tttttcttaa aaatacaagc cttatataat catcatttat ttctaaattt
    29581 agaatttttt taattgtagc catctccttc ttaaataaaa ataaatttta aaacttacaa
    29641 caatcaatat aaaatattat tttggataaa attgcttaga atttatattc acgcttatat
    29701 ctgttccgtt atcatttata acaagttcga atttacctga tgtactctga ggaactggaa
    29761 cagtatttag gtatcccttt tccttcaatg cttctacact tagagagtct attatatttt
    29821 catcatcatt aattgccata ctagctgctg ttactatatt agcagcattc gtatagtctg
    29881 catttaattt agcactttct tgaaccttac tatacttaac taatgctata ctagatataa
    29941 ctcctaaaat agttactact acaatcattt caacaagtgt aaatcctttt cgttttttat
    30001 ttatcaatta aatattctct ccttttcaaa agtttcatct aataaaattt atttttcttt
    30061 ctaaaaacta gtaattgcat caaacatagg aacaaccatt gccaaaacaa aaatgccaat
    30121 aattaatccc ataaagacaa ttagcacagg ctctataaat ttcattattt gctctatttt
    30181 gttatttaat tcattttcat aaaatttatt tattacatct aggcttttat ctagtttgcc
    30241 actttcttct cctgtatttg tcattgaaat aaataatttc ggaaaaatat ttgctaaatt
    30301 caaggattta cctatgctat ttcctttttt tatatagtta ttagaaattt ttagcctttc
    30361 ataaataaat tcattgtcta taacactagc tgacatatct atagcttcca caatttgtat
    30421 tccactacta attaaaatgg acaacgccct tgaaaatctt gttgtagcta ctaattgatt
    30481 aattcttttt acaaatggta ctttaaattt taatgaatta gttaattttt ttatattatc
    30541 atttgttata aagaaataaa tacttcctat tgaaaacaat ataaaactaa atatcagata
    30601 agctaaatta tttgtaacca ctgtagatat tcccattaaa actctagtta ttaaaggtgg
    30661 ttcaattcca ttactggtaa aaaccacctg aaaattaggt attacaaata cgaatataaa
    30721 caacattgat aagatagata atattataag tattattgga taaattgaaa tagttattat
    30781 ttttattttt aatttgtatt ctttatcata ataattagat aaatcgctca ttattatatc
    30841 taaattccca ctagtttctc ctgcttttat catacttata aagaatttag aaaatatacc
    30901 tgttatttga aatgattctg ctattgagtt acctttttga atatgatttg atactatatt
    30961 aagcaaattc tttacttttt tacttgactg actctcaatg atttcaaata tctttgtaat
    31021 ttcacatcca gattccatca gtatgcctat ctctttgcaa attactctaa tttctttatc
    31081 actgattcta tttaatacta aataaaactt ttctaaatta caaaatatat ttttagataa
    31141 tctcatatac tataatacct tccaaattat attaattaca attaaataaa cttaatattt
    31201 tctaatttaa tacatttaat tttattttac ttgaatataa tttatactca aacatcttaa
    31261 ttaaaataga ttaaataaat acaattgagc aaacgaaatt taactattca attcagtcaa
    31321 atcatttcat ttactactaa acactcttct aatgttgtta ttttttcatt tattagcctt
    31381 ttacaactat cttcaaatgt tatcattcca ttattttgtg ccacgtcttt aatagtacta
    31441 gaatcctcca tatttcttat acatgtcttt atatcatcat taatttctaa aatttcataa
    31501 attgctgttc ttccaaagta tcctttatca ttacattttt cacaacctac agctacttta
    31561 gtatttacat ctccactaaa atcatctttt atcataatct catgactaca atgattacaa
    31621 acttttctaa ccaacttttg agatataaca cctataagag atgcgtttaa aagatatggt
    31681 ggtatttgca tttctagtaa tctagctatg gaagatactg catcattagt atgtaaagta
    31741 cttataacta aatgacctgt tatagctgct cttactgcta ttttagctgt ttctgcatct
    31801 cttatttctc cgaccattat tatatctggg tcttgtctta atatcgctct aagacctaca
    31861 tcaaagctca accctacttt tgaatttact tgaatctgac ttatgccatc catcttatac
    31921 tctacaggat tttctatagt cattatattc ttatttattc cttttaaatc atttaataag
    31981 gaatatactg ttgtagtctt tccacttcct gtaggacctg taaccaataa tattcctgct
    32041 cttttattta ttatacgatt tatagatttt atagcttcct ctgaaaaacc aagttctagc
    32101 ttgtctttta aaaaagtatc tctattaagt atcctcaaaa ctattttttc accataaaca
    32161 gttggtattg atgaaactct aatgtcaatt aaatttccac ccaactttat atctacccta
    32221 ccatcctgag gaagcctttt ttctgttata tccattgatg cctttaattt tacaaccgta
    32281 gacaatgagg gatagacatc aactaaaaac tttgatactt cctttagttc tccatctacc
    32341 ctcattctca ctattaaatg ttctttaaat ggttctatat gtatatcact tgcattttct
    32401 tttatagctt tttctaaaag attttcaaat aatttttttg catagtcctc gtcaagttca
    32461 aagctattgt aatatttttc aatcttttca cttataagtt ctttcttctc tttcttcaat
    32521 ataatttctt tacctgtagc taatctcaag tcttgtagag cataaatatc ctcatcttct
    32581 atttctacaa ctaaattatc atcttgaaat tcaactggaa atacattata tttttttgca
    32641 agcttttctg gtattaacat tggcaaactg ttttcctcta atataatctt aatcaccctt
    32701 tatatacttt aatttattag gtatattcat ttttttcata gagatatttt cttcagtttt
    32761 tatgcttatt ttcattggat aattggtttg tatgctatct aaatatttac tacctttatc
    32821 tacataatta gatagtttct ccttatctcc aatgcacttt atttcatatg gctgtgctac
    32881 aggaactcca tttatattta tatggcttcc tgcaaggaca acttctgaat attgattaat
    32941 tctttgacca tttatttcta tgtattttcc tccatttaat tttaactcat ttatgacttt
    33001 tacaagaatc ttattatagt ctatactatt agctatatta cctgtttttt catctatagc
    33061 atctatactt aatattatcc cactaccctt catatctgaa tatgatagac tatctctaag
    33121 cgtttctatt tgtgatattt tttcagaatt tttttgattt tttttcattg aatcaatttc
    33181 tttatctaac ttgcctttct ctttggttaa ttcttttata gattttcttg tcatttttat
    33241 ttcttttctt attgacttat ctttgcttgt ataaactgtt tcttcattgc tataatctct
    33301 aaatatggtt ccaacaagta tacctaaaat agtacttgct agtattataa acacatattg
    33361 ttttttcata ctgtattgct ccttacaaat ttatttttat gtgataattt tctttaatta
    33421 aatattaaac atttacatac gtttattata tcaaagttat atattaaaat tcacctttag
    33481 tatataatat catatattga actcctatca ctaacttacc aatatcaagt atgtattttt
    33541 aaatgttatt aaaattatat aaactttcaa taaacattgt tgtaatatta taaaaaacat
    33601 aaattagaaa aggagataat aatcatgaaa aaacaaacaa taaccttagg attaacaagt
    33661 ataatagatt tatgaggaat tggtttactt aggcaaatca tttgcagata aaaatactgt
    33721 taaaaaaaat ttcaactaac tattctggat atgacatact agaaaaatga aattcaacta
    33781 tttctactgg ttttagttca aagtaaattc atcatacgct tatattttca atcaaattat
    33841 ctttttttat ataacaattt atgattatta ataattattt tctatcaaaa aagtaaaatg
    33901 gcatagcctt aaagctacac caatttacta aaaattatat cataattaac attaatgtta
    33961 aacatatgcg tttataagtt ttcctcatat tttaaaattc ttttaaccaa gttatctctt
    34021 aattttccta cttcatcaaa tctcatatta ggactatagt aactttctat aatatcatgt
    34081 ttagatttag ctctcttaag atttaacact gcccaacaaa ttaaatcatc taaaactttt
    34141 tcatcaaatt taatatcttc ttcatattta agtagttttt ctctatttaa aaactgattt
    34201 aaatcaatcg tatcttcttc tttaaaattc gtgcttatag ttatacctat atctaagtca
    34261 gttaatagta tagtttcaat tttctctgga ataagtggat aatggtaaac ttctacattt
    34321 aaaccttttt caatagcttt attatacact ttgtttaata gtgtagtttt cccagttcct
    34381 atttctccag ctaaataata aaccttattt acatctttta aaatgttttc tgtataatct
    34441 aaacacccta caggagttat agctgaacca aataaatgct tttctctttt tagatttcct
    34501 gtgcttttaa ctccatcaaa taaccttttt ataaattctt ctgtgactaa atttacttta
    34561 ccataatcca tacaatcaga atatttttct tctatgtctc taaagattgg ttctgccgat
    34621 tttaaaaact taaatgctct cttaaatgaa ttactaatat ctttatcgta gactgatatt
    34681 tcttgtctat tcttttctaa ttcttctgta ttccaataat cacctagatt aattatctcg
    34741 tccaaagctc caggtagctt tgggtccata gtatgtggag cagttgcatc cataagtacc
    34801 actcctaatt tctttataac taagccatcc aacgaacttg ggtcagaagg acaatgatat
    34861 aaatcaatat catatcctcg atgcaaaaac tctttataaa tttttttcat aagtgaggat
    34921 tttcctactc caggtccacc ctttaaacaa aaaactcttt ttacattttc aggaattata
    34981 tagtcaaaaa aagaatatga gccttgtgat gtatttccac ctgggaatgc cttctttacc
    35041 tttccttcca tattagcgcc tcctcataat ttacaatatc tcttaattaa gatattcata
    35101 ttataagaat tttattacag ctttctgatt ttgacaaatt taaaacttgc tatctaatac
    35161 taataacagg ttcattttat ctaattattg tagattctta tgctatgcct ttttatctat
    35221 aaatgcaatt taagtgtcca tatctaagta tttgtattgt aatatagctc tatattactt
    35281 aaatccaatt gtttccatta taattttatg ttaaaataat attacaaaat acatctgttt
    35341 ttcttcataa acgggtgaaa ttccctatcg gcggtaaaag cccgcgagcc ttatggcata
    35401 atttggtcaa attccaaagc cgacagtaaa atctggatgg tagaagaaaa tagtatatga
    35461 gtacctttat gtaattttac atgagtaatc tatacaaatc cttcaactac cgtatttatt
    35521 catgaaatta gacacattca aggtacctaa tatacaggtg ctttttttgt tgtttatttt
    35581 ataattatat cgtacttata aaatctatta agattggagt gttatcatga aacaaaaatg
    35641 gatagtattg attatcatct gtattggtgt atttatgtct actcttgatg gaagtatact
    35701 aaatatagca aatcctacaa ttgctgctga ctttaaaatt aacatgtcac aaattcagtg
    35761 ggttgtaaca gcttatatgc ttgttgtaac agctactatg ttatttttcg gaaaacttgg
    35821 cgataaagta ggctcaaatc gtctatacac attaggattt tttatattta caataggttc
    35881 ttttctgtgt agtatgtcaa acaatttatc aacattaatt tcttcaagaa tttttcaggc
    35941 agttggagca agtattttaa tggctaccgg acttggtata gtttccaatg catttccaac
    36001 aaacgaaaaa ggaaaagcta tcggaatcac tggagctgta gttggtatag gaaatatgag
    36061 tggacctgta attggaggta taattttaga acattttgga tggccttcta tttttattat
    36121 caatatacca attggtatta tagcagtctt tcttggtatt aaatttcttc ctaagcctgt
    36181 tttagatgag caaagcaaaa gctttgatat tccaggtctt ctacttttcg catcttgcac
    36241 tacgcttata ttacttgcaa tgaatgagaa aggtaataca agattgtatt taggtataat
    36301 agcacttata atcttcttgc tattggcatt gagagaagta aaatttgaac aaagttttat
    36361 tgacctacct ctatttaaaa atagaaactt tactgtaggc aatatcattg gagtagcttg
    36421 ttattttcct caaatggcag tatcttttct acttccattt tatttagaac aattaaaaaa
    36481 tttatctcct atgatggctg gttctgtaat gactgtacat ccacttatta tggtacttat
    36541 agcacctatt gcaggttctc tttctgataa acatggtgca aaaaatattc taacagcatc
    36601 tttttcattt atgaccatct cactagttgg aatggcactt ttaaaagcag attctccact
    36661 gtatctttta attgtatgtt tagttatttt tggacttggg ctaggagcgt ttagttcacc
    36721 aaacaatagt agtattttag cagatgttcc tcctcaaaaa cagggatatg gaggcagttt
    36781 tcttgcaact gttcgtaatt tgtcatttgc tcttggaaca gcatttttta gcagtttttt
    36841 tgcacaaagt cttacataca atcaaaagtt caaaagtcac acatcagcct atgttatagc
    36901 tagcaataaa tcttattgga ttgcagcatc agtatgtttt atagggctta tactaactgt
    36961 tttctttatg agaaaaacag ataaatctat ttcttaaata aaatttattt ctgatttcat
    37021 cagtgattaa attcttaaat atactaattt atatcaaact ttacagtttt tttctaattt
    37081 ataacaataa attgctaata tttattgttt ataaacaaca aggatgccaa aaaatgtcca
    37141 ttaaaactat tttgaggcat cctatatttt attttgatat taaaacagtt agaactaatc
    37201 taatgttatt ttatatagat tatttaaaca agtattacgc caacatttga tagtttaaat
    37261 ttaatccact gttatctcat atccatgttg attatattga tttacaattt cttcccatag
    37321 ttcttcaaca ccagtctttt ttagtgaaga aacaggaatt actttttcgc tactttccat
    37381 ttgcaatttt tttcttatta tacttatatg tttttgatat tgacctctag atattttatc
    37441 tgccttagtt gcaataacta cacagttata tccaaagtgc tttatccatt catacataag
    37501 cttatcatct gctgtaggtt catgtctaat atctacaagt aggaatatag aacataactc
    37561 ttgtctactt tctagatatc tttccattat acctccccac ttttcttttt cagacttagc
    37621 tatctttgca tatccatagc ctggaaggtc tacaaaataa aattcattat ttattaaata
    37681 aaaatttata gttctagttt ttcctggtgt ttgactagtt ctagcaaaat ttcttctgtt
    37741 aagcaatgta tttattattg atgattttcc aacatttgac ctaccagcca atgctatctc
    37801 tgggattcct tctgctggat actgtgattt attcacagca ctcatggtta tctctgaact
    37861 tctaattttc attattttca ccactcttta ataaagcttg ttctaatact tcatccatat
    37921 gctctacaag cacaaactcc attttttctt ttacattttc tggtatttca tctaagtcag
    37981 cttcacactc tttaggaatt aatacttttg ttataccagc tctatgagct gctaataact
    38041 tttctttaac tcctcctact gctaatactc tacctcttaa agttatctct cctgtcattg
    38101 ctatatttcc aggcacaggt cttttagtaa gtgctgagat tactgcaaga gccatagtta
    38161 taccagctga tggtccatct tttggaacag caccctctgg aatgtgtata tgaatatcat
    38221 tcgtcttata aaaatcaggg tctatatcaa acttgtccac tattgacctt atataagaga
    38281 tacctgtctt agcagattcc ttcataacat ctcctagctt tccagttaat acaatttctc
    38341 ccttaccttt aagtacattt acttctactt caagtgtaac tccaccaact gctgtccatg
    38401 caagaccatt tactaatcct atttgagggt taacttctgc aagttgatac ttaaacatat
    38461 cttttccaag atatgcctct aagtcagact tacttataac aacttcttca agagttgggt
    38521 cttcaacgta ttttttggca acttttctac aaatcttacc aatagttctt tctagtgttc
    38581 ttacaccagc ctcccttgta taatgattaa ttatacttct taaagtttca tcatctattt
    38641 ttataaagtt ttcttttaaa gcatgttctt taatttgttt tggaagtagg tatttttttg
    38701 ctatatttaa tttttcttct tctatatatc cagatacttc gattacttcc attctatcta
    38761 ataatggtct tggtatatta cctaggctat ttgctgttgt aacaaatagt atttttgata
    38821 aatcaaaagg tatttctaag taatggtcca caaaatcctt gttttgctct gggtctaata
    38881 cttctagcat tgctgaagct gggtcacctt tataatctgc tgccatctta tctatctcat
    38941 caaataagaa cacaggattt tttgtttgag cttcttttac cccattaatt attcttcctg
    39001 gaattgaacc tacataagtt cttctatgac ctcttatttc tgcttcatct ctaactccac
    39061 ctaaagatat tcttacaaat ttcctattta atgctctggc aattgatttt actatagatg
    39121 tttttcctgt tcctggagga ccaactaaac atattatagg acctttaagt gacttagcaa
    39181 gagttcttat agctagatac tctagtattc tctccttaac tttttctaat ccataatgat
    39241 cttcatctaa tatatctttt gccttagtta tatctaattt atcttttgtc tctttattcc
    39301 atggtaatga gaatatagta tctaaatagt ttctgcttac agatacatct ggagacattg
    39361 aagatatttt tgaaaattta tctatttctt tttctatttt ttctttagtt gtcttaggtg
    39421 cttttatttt tttaagcttt tctctatact catctgcttc agagtttata tcttcttctt
    39481 cacctaattc tttctgtata gcttttaatt gttctctaag ataatattct ttttgaactt
    39541 tattcatctg tttttttact cttaaagtta ttttcttttc tatttttaat atatctattt
    39601 cctctaataa tatagaataa ataagttcaa gtctttttct aatatcaaat tcttctaata
    39661 tttcttgttt ttggcttgat tttagatata tgtttgcagc tatcgtatct ataaatctat
    39721 ctacatcttc tatatcagct aaagatatta atatttctgg tgatacccta ttcccaatat
    39781 ttatatactc ttcaaaggca tcaaatacat ttcttacaaa tgcttcaatt tcaacttctg
    39841 tctcactatc caaattatca ctatcaaaca ctatttcttc tattactgct ctgaaatatc
    39901 catcttcttg ttctattttc tttaccttac ctcttgatac accttcaact aaaacacgaa
    39961 ctgtatctcc tggtaatttt atcatttgct taactttaca gattgttccc acatgataaa
    40021 aatcctcttc tcctggctca tctacctctg cttctttctg agaagttaaa aatataagtt
    40081 cttcatccat catagcttgg tctaaagctt taagggatat ctctctacct atatcaaaat
    40141 ttaatatcat atatggaaat atagctaatc ctcttagagg aattaatggt aattcatgat
    40201 ctattttagt ataattttgt tccatcaaca ttactccttt tctagtctaa ttgctttgct
    40261 tttaatatta tatatttgaa caagttaatt ttcaacatta atgataaatt cttagaatac
    40321 tatcatacta tattatcttt ttattatgat ataatattaa tattagtata cttagatgtt
    40381 atttatcttt tggaggtttc tattatgttg aaattgtttt taaccttttt aaaaattggt
    40441 gcgtttacat ttggtggtgg atacgctatg gttcctctta tacaagatga acttgtaaac
    40501 aaacaaaaac ttttagagca ggaagaattt attgattatt tatccatagc tcaaagttat
    40561 cctggagtac tggcagttaa tatatctgta ttattaggat ataaacttta tggtatacca
    40621 ggagttctta tatgtacctt aggctctgct ttaccatcat tttgtatagt cttagtctta
    40681 tcgtatctat actttaaaaa ttcatcatct aaaattttag atggattttt taaaggagtt
    40741 gcgcctgttg taatagctct tatattgtat tcttttacga gcatgttcaa gaaactacca
    40801 aagtctaaaa ctaacatact actattaatt atagcagttt tatctgttgg tgtattcaat
    40861 ataagcccta tttatttaat aattggagga ggtgtatata gtctatgtca gaaataatac
    40921 tactcttctt aatattcctt aaaatagggg catttagttt tggtggcggt tatgccatgc
    40981 taccatttat ccagcaagaa tttatatcta aatatcactt tataactaat caagagtttt
    41041 tggatttact tgctatatca caatctacac caggtcctgt agcaataaat agtgccacat
    41101 ttgtaggatt taagactgct ggcttctttg gttctctagc tgcaactgtt ggtgttacaa
    41161 tttttgcatt aataggtcta actattatat caaagttatt ttctaagttt aaaaacaata
    41221 aaaaagtaga aaacttattg acagttctta gaccaattac tctaggattc atattatcag
    41281 cagctttttc atctgccaaa gaagttaact gggatttata tggaataatt gcatttatag
    41341 catcatttta tcttttatat aaaggaaaaa ttggttccat tgcaattgta ttcgtctttg
    41401 gtattctagg tatattactc acatttttat aataatgata cctattatat ttagcatatt
    41461 agcataaaaa aaggagcttt taaagctcct tttcatcatc ttatgcactt tcctcttgat
    41521 ccttaagtac tatgatagga tttactgagt cttcgttcac agatttctct gttactataa
    41581 ccttctttat attatctcta gatggtactt caaacatagt ttccatcatt acactttcaa
    41641 ctatacttct aagtcctcta gctcctgtat ttctttctat ggctttttta gcgattgcac
    41701 gaagagcacc ttcttcaaat tctagctcaa catcatctaa ctccaataac tttttatact
    41761 gttttactag agcattttta ggttcctgta atatctgcat taatgcatct tcatccaaca
    41821 actctaaagt agctaaaact ggtattcttc ctataaactc tggtattata ccatatttta
    41881 ataaatcctc tggaagtact ttttcataca acttccctaa atctaattct tttttacttt
    41941 ctattttagc tccaaaacct agtgttttat ctccaccacg tttttgaatt atcttctcta
    42001 atccatcaaa agctccacct aatataaata atacattagt agtatctatc tttaaaaatt
    42061 cttgatgagg atgttttctt cctccttgtg gtggaacatt tgcaacagta ccttccaata
    42121 tttttaaaag tgcctgttga acaccttcac cactaacatc tctagttata gatgggtttt
    42181 cagattttct tgcaatctta tctatctcat ctatatatat tatacctctt tcagcttttt
    42241 ctatatcaaa atcagcagct tgaataagtt ttaaaagtat attttcaacg tcttctccaa
    42301 catatccagc ttcagtcaat gatgtagcat ctgccattgc aaaaggtaca tttagagttc
    42361 ttgctaaagt ttgagcaagc aatgtcttcc cagaacctgt aggtcctaat aaaagtatat
    42421 tactcttttg aatttctata tctttgctac tagatttttt actatatatt ctcttgtaat
    42481 gattataaac tgcaactgat aaagcttttt tagctttttc ttgacctatt acataatcat
    42541 ttagaatctc catcatttcc tttggttttg gtaaagatgt agtatcctca tctatagtat
    42601 cttctatctc ttcttgaata atttcgtcac aaagttcaac acactcgtca caaatatata
    42661 catttggacc tgcaattaat cttcttactt gatcttgatt tttaccgcag aatgaacact
    42721 ttaattgtcg tttttcttca tatttagaca tattaacacc tctctctatc tacggtctct
    42781 ttgtaaatac ttcatctatt aaaccatatt ctttggcttc tagtgcactc atgaagttat
    42841 cacgttcagt atccatttta attttttcta atggctgacc agttctttca gataatatct
    42901 catttaaagt ttcttttatt tttaaaattc tctttgcatg aatttctata tctgttgctt
    42961 gaccttgagc tccacctaat ggttgatgta tcattatttc actatttggt agtgctagtc
    43021 tttttccttt tgctcctgct gccaacaaga atgctcccat agaagcagcc atacctatac
    43081 atatagtact tacatctggt ttgatgtatt gcatagtatc atatatagcc attccagaag
    43141 ttatacttcc tcctggagaa tttatatata aatgtatatc tttgtctggg tcttcagctt
    43201 ctaaaaataa tagctgtgct actataagcc ctgctgtggc atcgttaact tgatctccta
    43261 agaagattat tctgtctttt aatagtctag aaaaaatatc ataagatctt tctcctcttc
    43321 ctgtttgttc aacaactaca ggtactaatg ccatggtttc ataccccctt tattctatat
    43381 aatttacagt agcttttttt aagctactgt aaattattat acgcatttaa ctaaattata
    43441 tttgcacatc attatatact aaacatttca taacgtcaac tatattagtt agcgtttatt
    43501 ttattaagct attgttgcat tatcaactag taaatctatt gtttttctta tttttatttg
    43561 accttttata tcttctttgt cagcatctct taaagaagct tctatttttt ctacttccat
    43621 attgtaagca gaagccattt tttctaactc agccttaaat tcttcttctg ttgcttcaat
    43681 tccttcagct ttagttattg cttctaatac taaagaagat ttaactaatt ttttagcatc
    43741 ttcttttctc tcttctctta attcttccat agttctacca gtcatctcta ataattgttg
    43801 taatccaaat ccttgatatt gtaattggta gttaagttca tttaacatat tatctatttg
    43861 atgttgtatc ataacttctg gtatttctat ttctgtattt tcagcaactt tttctactac
    43921 tgaatttcta gtttctgcat ctgctctatt tttagcttct tcttctaact tagctcttac
    43981 atctgctttt aattcatcta aagaatcaaa ttcactagta tctttagcaa attcatcatc
    44041 aagtgcagat aattctttta cttttacatc gtttattttt acattaaata caactggttt
    44101 tccagctaaa tcttgtgagt gatattcttc tgggaaagta acattaactt ctacttcttc
    44161 accagctttt ttacctacta attgctcttc aaatcctggt ataaatgtgt ttgaacctat
    44221 aactaagtta taattttcac ctttaccacc atcaaaagct acaccatttt caaaaccttc
    44281 gaagtctatt atagctgtat ctccatcttc taaagcttta tcttctacac ttactaatct
    44341 agcatttttt tcaaccattt cttgtagttt agcatcaaca ttttcgtcac ttacagtatt
    44401 ctcaacctta gctatttcta tacccttgta gtttcctaat tcaaactctg gtttaacttc
    44461 tacattaaga accataacca acccattgtc tttacttatt tcctctatat ctaaatctgg
    44521 attgtctatt gggtctatgt ctaattcctt gatagcttct ggataaactt ctgggaataa
    44581 tatttctata gcatcattat agaatatacc ttttccatat tgagtttcta taacaattct
    44641 tggagcttta ccttttctaa atccaggtat attgtattta tttctgcttt tattataagc
    44701 cttatttact gctgcttcaa atttattgtt atctactgtt atttttaaag taactttatt
    44761 accctctttt ttaattagtt ctgctttcat ccttctaatc ctcctagtga tatttatgta
    44821 atacccgata acggtattat aattcattct atttataatt caaccactta attatatcac
    44881 ataagttttt ttatttacaa gtgttccatt aatatcgttg tacttatttg ataaaattta
    44941 attttttgag cgttttttgc cattttttta gataaataca cctttatatg cgtatttctt
    45001 ctatatttat gttatcttct tctatatcca taatgacaaa acttttatac gatactcctc
    45061 ttggaagtga agtacttcca ggatttatgt aaagtacacc atctttaatt tctctaaacg
    45121 gagtatgggt atgaccaaat ataactatat cagcatcaat ttcagttgcc tttttttcta
    45181 acatatgcgt tccatatttt acaccatact tatctccatg acataagaat atagttttat
    45241 ttgccacttc aaagacaact tcttcctcaa cagcatcaaa gtcacaatta cctttaactg
    45301 caataatacc tacattagtc atgctatgaa tatatcttga atctgtaaag ttatctcctg
    45361 catgaattat taggtcacat tcttttaaat atggtattgt tttttccata tttttaatca
    45421 tcatatgtgt atcgcttact atgcctattt tcattacttc actacccttt ttataaactc
    45481 ttgtttcata agttttagtg catttgctct atgactgatt gaatttttta taacactagg
    45541 tatttcacca aaagtcttat catatccttt tactataaat aaactatcat atccaaaacc
    45601 atttttacct ttttcttcaa atcctatcat tccttcacaa attcctctta ctacaaattc
    45661 ttttccatca ggaaaaacta cggctattgc agagacgaat cttgcatttc ttttactcat
    45721 tggtacattt tgcatagctt ttaacagttt ttttctattt tcttcatccg ttgcatgttc
    45781 tcctgcatat ctagctgaat aaacaccagg ttttttgcct aaagcatcta cttctaagcc
    45841 agaatcatct gatattgcta taagtttagt cttttttgct attgttctag cttttatcaa
    45901 cgcattatgc tcaaatgttt ttccatcttc tactatatct atacctgcta aatcaacatc
    45961 ttttaaagag tatactttat actcaaaatc ttttaagatt tcacctattt cttctagctt
    46021 atgagcatta ttagtagcaa tcactacttc attaccataa tccataccca atatttcatc
    46081 tgctatttca cctaaagctt ctttttgaag ccttattaat tctttattcc ctttttcacc
    46141 taactctaac aataaattta aatctgttct cgaaaaaggt ttctcttctc cagtcccctg
    46201 tacttctaca aactcacact tatcagtcat tattatattc atatctacct gtgctttaga
    46261 gtcttcttca tagcataaat ctagcatgtg tgttccattt acaataccaa cactaattgc
    46321 agatacaaaa tttgttattg gcatttcttt tactgtcttt gctttatata atttatatat
    46381 tgcttctgca actgctacaa atgcccctgt tatagatgca gttctagttc caccatctgc
    46441 ttgaattaca tcacaatcta cccaaatagt tctttcccct aatttattca agtctacaac
    46501 agaccttatt gctcttccta ttaatctttg tatttcttgt gttcttccat caatttttcc
    46561 cctagatgca tctcttatct ttctttgttg tgttgctctt ggtagcatag aatattcagc
    46621 atttatccat ccagtgccac tatttcttaa aaaaggagga actttttctt ccactgatgc
    46681 agtgcatata acctttgtct ctcccatttc tataagaaca gaaccttctg catactttgt
    46741 ataatctcta gttatcttta caggtcttat ctgctcgtta cttctatcat aacttctggt
    46801 cattttttat atcctttctt atatttttgt tttttataaa tttattttta taatttttaa
    46861 ttttgtcaaa tattaattat tgtcattttt cgtaatctta ttagcttact gaactattct
    46921 atcattaatt atagtagttt tctactaaat taagcgactt tttaactctc taatatagct
    46981 tttacttcat ctttcgatga taactttaat agttctaaaa atctctcttc atctataact
    47041 ttaattccta aatcatttgc tttagcgagt ttagaaccag cttcttcacc tgccaaaaca
    47101 aatgttgtcg atttactaac actagatgta gcttttccac ctcttttttc tatcatatct
    47161 tttgcatcat ttctttttaa tgtaggaagt gtaccagtca atacgatttt catcccttca
    47221 aatatttttt ctactttttc acctgtatta tccaatgatt ttgtatttac tcctacattt
    47281 tttaacttgt ttataacgtt catatttttg tcttccttaa aaaactcgac aacgctgttt
    47341 gccattatac ttccaaattc ctctaattct tctagttgtt cactcgttgc agacatcaca
    47401 tcatctaaat ccttaaagtt atatgcaagt atcttagctg ctttaactcc tataaattta
    47461 atacctagtc catttataag tctccataaa tcattttctt ttgatttttc aattgaattt
    47521 attaaattgt cagcagattt ttcgcccatt ctctctagct cgactacatc ttcctttttt
    47581 atataatata aatcagatac atcttgaata attttttcat ttaatagcag tgtaattata
    47641 gattctccca atccatctat attcattgca tcccttgata caaagtgtat aattcccctt
    47701 cttatttgag ctggacaaga catgtttata cattttacag cagcttctcc ttctaatctt
    47761 attgttggct ctgaacaaac tggacacttt tctggcattt taaaatctat ttcatctcca
    47821 gtacgttctt cttttataac ttctaaaact tgaggtatta tatcccctgc tttttgaact
    47881 aatactgtat catttatttt tatatccttt tctcttatat aatcttcatt atgaagtgta
    47941 gccctgctta cagtagtacc tgcaagtctg actggttcaa gaattgctga aggtgttatt
    48001 gtaccagttc tcccaacttc tactattata tctactattt tagttttctt cttttctgct
    48061 gggaatttat atgcaattgc ccatctagga cttttggctg tatatcccat ttcgtctctt
    48121 tgttttatat tgtttacttt tattaccata ccatctattt cgtattctaa attacccctg
    48181 ttatctgtcc aatattcaat gtgttcaata acttcatcta tacttttaca aactttataa
    48241 ctctgactta ctgaaaatcc tagtttttct aagtactcta gcgagtcact gtgactttct
    48301 aaatcgtaat cttctatatt ttccatatta aatacaaata tatctaatgg tctctttgca
    48361 gttagttttg ggtctaattg tctcaatgaa ccagctgcaa gattccttgg attggcaaat
    48421 aatggctgtt cttgttcttc ttgttgttca tttacctttc taaaattatc ttttgatata
    48481 tatacttctc ctctaactat taactctttt ttatcattta tcttaagagg tatgcttttt
    48541 actgtcatta ggttttgaga aatatcttct cctacaactc catctcctct agttgctcct
    48601 ttttcaaact ctccattatt ataagttaga cctacagaaa gaccatctat tttaaattca
    48661 acaacatatt caacattttc tccaacatat tcttgaaccc tcttatcaaa atccctcaaa
    48721 tcttgctctg aaaaagcatt tgataaactc aacataggag ttttatgtac aatttgattg
    48781 aatttatcta atggcttacc tcctacccta tttgttggcg aatcaattct cttcaattct
    48841 ggatgttctt cttctaaaga aattaactcc ttcattaact tatcatattc ataatctgat
    48901 atttctgggc tatcttgatt ataatacctt tcattatggt aatttattgt ctctataagt
    48961 ttattaattt catcttttat gctcactttt tgcacctctt catatttttt aaattaaatt
    49021 attttgaaat ttccttataa ttaattatct cctatttata tattttttag tatatcactt
    49081 ttttgacttt aaatttatta caaaaaaaac tcttattagt atatctaata cgactaataa
    49141 gagtttttta tttttatcaa aattttttat ttttagtatc ctcttgatat gtctacaacg
    49201 ttatctacag gtttattttc cagtatatag tgtttcaagt tattataaac catattaaat
    49261 gttctctctt tgtttttatc tgacacccaa gaattatgag gagttactat gacattttca
    49321 cactcccata acttattatc cttgtttaaa ggttcacttt caaatacgtc taatgctacc
    49381 cctctaaatt tttctataca ttcttctaaa tctttctgat taactgtatt tcccctacct
    49441 acattgataa atacagaacc atctttcata agtttaaaca tatctttatt tactattcca
    49501 tctgtgcttt ttgtagaagg cattgctaca actactatat cacattcttc aaatacaata
    49561 ttcatatcct cagtggcaaa acacttatca aagtattttt tactacttcc cgcagtattt
    49621 acaccccata tttctagacc aaaagctttt aatctttttg ctgcttctga agatatagta
    49681 cctgttccta aaaatccaac tctttgtcca tacaattccg atacagaaaa atccatcttc
    49741 cattctttat tttgttgttg tttaaaaaat tttgcactat ttttatatat ttctaaaata
    49801 tacaatacaa tgctttcacc aataggtaca ctatatccgc ctctattatt agctatctta
    49861 atatttctct tcaatacttc ttcttttgga agttggtcta tacctacact tgttgtctgt
    49921 atatattgta aatttttcat cttagagata tctaatctct caaatggatt gtatgtaact
    49981 agtacatctg ctgtatttac atcctcatta ttttcaataa tatcttcaga ataatgtatg
    50041 acatcatagc ctaaatctct tattttatca aatttttctt ttccataatt tattgtaaat
    50101 aaaactttca tctcaaatct cctccatcta ctcacattaa aaattttata ttctaaagta
    50161 taatatgata ctcaatgcac attagttaaa attactagaa gatatcttaa atttacttat
    50221 gttcaattgt ttttcctaaa gacatagcat tacgttcttg aactaaattt tctattaaat
    50281 tattcaatgt ccaatcaata gatgtctctg ttaccatagc tgtaaaaggt ctatttatcc
    50341 tcactttttt tagtccttct aaaaatgcat ttacctgtgt acttggagcg ttattaaata
    50401 ttacagactt actcttaatc ccattttcac attcacttga tatatttcca tctaaaatgt
    50461 ctcttattat attatctcca tttttatcac ttaagatgat atggtctctt attccagcaa
    50521 agttacttac atttttaatt aatgataatt cttttttatt aaaatttaca agcataatac
    50581 acttcctatt gtgtatttta tctaggttat tattatttat tttttcaaat gacattttat
    50641 ccatcctttc atttatttat atattttaat ttaccccata catttaaaat aatcaatttt
    50701 tatagttaat ttttatatta atacccaaat tatatttaaa tagttagact atccaaaact
    50761 aatatataaa attagaataa ttagattaat atctacaaat cataacctaa aggagagata
    50821 ccatgaatac attactaaac aataaattta gcattaaaaa tttttcaaat gcttgggtta
    50881 tagtgcttgg ttgtatgttg atacaagctg ttccatttag tattgtagca agtatacaac
    50941 ctcaatttat aagttatgtt gtagaaggag aaggctttag tttagcttct ttttctctaa
    51001 tattcactat tggtactatt gcctcagcaa ttgcatcacc ttttataggt gtattatttt
    51061 ctaaagtcaa tattaagata ctatatttat taggttgtat aatttctagt attgcttttg
    51121 ctactttttc tatatgtact gaactatggc aattttacac ggtatcatgt attgttcaaa
    51181 ttggtgctac aattatatct gctataggaa tacctgtttt aataagtgct tggtttgatg
    51241 aagaaagcaa aggaaaagct ctaggctttg cttttgctgg tggttctatt ggtagtatat
    51301 ttctacaacc acttgcagtt cgcttactat caactcaagg atatagtcgt tcttatctaa
    51361 tatttggaat tgtagcatta atagttggta tacctgtaat gtatatcagg tgacaccgta
    51421 tgatatgatt ggaacgccat tctaatgcgg tatctacggg atttgttgaa aagtcaaagt
    51481 atcgtaaaat gatgtcaaat attgggctgt atcgcaaaat tgggagtaca aagggagtac
    51541 agaaaaaatc ctatgggagt acaaaaagta tgatataaac tgtcttttgg aacaatatta
    51601 tgagggcgta ttgtgtaagc gatatgctct ttaatttttg agaaaagtaa tgctacagac
    51661 taggaaatat gatagaatga cagaaataaa taggaattgc agtattgaga atgaggaggt
    51721 ttagtttatg caatatttat tgataattat cataggactt ttgcttttta ttgaagttga
    51781 taagttgaaa aaacaggtaa aatcacaaca aaagcagatt gatactttgt gtgaacagac
    51841 ggggaataat caactggcaa cgtatcatat atcggatgag gataaagaac ttattcttca
    51901 tttgaaaaat agtggaaaag atgtagaggc tgtgaaaaaa gtaagagaga ttactgctat
    51961 ggaattagaa gaagcaaaac aatatgtaga ctctctttaa gagttcaatt ttctgatata
    52021 gtaaaaagta agatttggat aatggaggtg ttcaaatgga taaaagacat tggttcttac
    52081 ttggttattt aattattcca gtatgctttt ttgttgcagt tattgtagtt ggtttgctaa
    52141 gaagtcattc tttaattgaa atttataatg acggattagg aattacggca ttatattacc
    52201 ttttacttag tctgtttgta tatattcgct ggcaatattt ttctgacaaa taaagaattt
    52261 aggaggttaa gaaatgtata ttatttatac agtgttagcc gctatagtgg gtatggcttt
    52321 ggtagttacc gttgatatgg gaataacaaa gatatttgat aaaaagagca tttttcaaaa
    52381 aaattatatt aagatgccac tttcttattt cattgggatt tttgtttttc ttttgattgt
    52441 gagattgatt ttttcataaa gaaatagagt tgtaaattca gctttgtagc agacagtttt
    52501 aatgtaactg tctgcttttc ctttttaatc ataattgata atagtgctat aaaatggttc
    52561 atatccattg tgaaaagacc atttagagtg atatagattg attataagag tagtaggagt
    52621 cccgttgatt tgattatgtt ctgcttcgat ttccgctacc acttcatcgg tattccagta
    52681 ttgatatacg ataacttgca attcggtatc acgattagcc ccattgctga atgacatact
    52741 gttaaataca agataatcgg gcaagctaat gtaatagaga atgcctgcaa gcaagactag
    52801 aataatagtg gcaaataaca atttcttttt cattttgaca tacctcagtt tctatatagt
    52861 tatagggata actatatagt acctcgctat atagtgaatt gctacataaa gatttattga
    52921 atatactttt atgtagaggt gaggcaatga agtatggaca tttggaactt cacatagagg
    52981 aactgctgaa agaaaaagga attagtaaga ataccatttg taaggaattg gatataccga
    53041 ggtctaactt taatcgttat tgcagaaatg aatttcagag attagacgca caactaatct
    53101 gtaaactgtg cagttacttg gattgtggaa tagaagaatt gatagagtat gtgaaagaat
    53161 gagagcctgt cggattgaag aaaattcgtg caggcttttg ttgtgtcaag aaaaagagaa
    53221 aacgtagtta ggtcaaggaa caaggcgaag ccgatacgcc gtagggcagt ccttgacgga
    53281 acggacatag ccaacagcac catgatacag tagaggactt gaaaggtcag aaaccttgca
    53341 agtcctcttg tctgttactg gtcgttatgt tttaagtaaa gtgcttcttt catcagttct
    53401 ttttcaaatg ccttgatgtg accgccctgt attccgttgt tgatatgaaa gcaatcgtca
    53461 gcctgtgagt aggatagcat ggtaactttc ggctcatagg tcttggtatc aattccataa
    53521 tagtaaatcg tggcggttgt taataccatg tgaatgcttt caaaatctct tgtaaaaatt
    53581 gtatgcctgt cggaatagaa gaaatcagac ggacattcat agaattggga actatcctct
    53641 ttcaaaaata gtggcagtat gtgcattgca tttccagcac gattgacaag gacataaaag
    53701 cgtggaatga gggcggcata ttgtgtcatc atggcgatat atatatcatc taaatcatca
    53761 agaagatact cagagcagga gttgttataa aagacatatt gcagggcgtt atcgttttga
    53821 cttgtatgtt ccataggcac attttgtccg taaagccaac gcaagtccac atctaaagag
    53881 tcggcaatca gttccatttt atcggctttc ggattgtact gtcctgaaag ataggaactg
    53941 aacgctcctt tgctgatacc agtatctttg actatatcta cttgtttttt attttttgct
    54001 ttcatggcaa atttaatccg ttctgcgatt gtattcatct gaaaaccctc tctttccata
    54061 tcccgttata acttttcata tcttatcgtc taaggacact ataccacaag ttcagaaaaa
    54121 agaaaataaa aagtttataa aaaactaaac tttgtgttgc aaaacaaata tgtctgtgct
    54181 aatatacaat taagtttaga aataactgaa ctaaaacgac gtcgtaatag gaaaatgaaa
    54241 atatgagaaa ctgacctatc ggttcaacgg ggagaaagga acgtgtatgc agattacatt
    54301 gacaaaagaa caggtaaaag aagcatttgg agaacttcgt tttatgggtg cggataactg
    54361 ttaccgctat gataaagaca gtaagaagaa aacagaggaa gtggaagcat taaaacttca
    54421 tcttggaagc atgaagcttg ggaacagcgt ggatattcgc ttggaagcga cggaacttcc
    54481 aaagattgag ccttatgctg tggtggaact ggaagaatca gtatatgccc cttatgtgca
    54541 gagaggaaac ttccctgtat tagtggagaa gattacctgt aagggtatcc gccctgttcc
    54601 aaacaaaaat atgtaggcgg tcaaagttcc tgccctcgtt ctgacgtacc aaacggcagg
    54661 ttgagggcag ggcaatggca acgccattgc agataggagg tatgggaaat ttggaagaaa
    54721 gaagcggaag ttttcttcca gaactcccct atactaacag gggagtaata cgacagaaag
    54781 aagcattaag tgccttgata gactggtgtc agataaccat taaggaagtt ccgttagaag
    54841 cagttataga agatgtgctg agaatacctt tggaacttat gacggtaaca ggctatgaaa
    54901 aggggattgc aggacatgag gttgtggcaa tcttcgataa tatcaaagtg ctaaagccga
    54961 caggaaatgc acagtatcaa ggctttcaga ttttgatgag tgggaaaggt tgtcgcaact
    55021 atgaaaattt tttacaactc aatgaggaaa catggtttga ttttttaaac agagtttgtc
    55081 agtaccacat caatgttcct cggattgatt tggcgatcga cgacagaaaa ccgtatttga
    55141 gtattcccga tttgattgta cggacaaaag agggattgct ttccacaaaa ctaagggaga
    55201 tagattttca cgactcggga gagctgaaag aggaagtgtt tcagagtaag ggtggtagtc
    55261 tttatctcgg cagttcagcc agcaatttga gattggtatt ttatgaaaaa ggatatgaac
    55321 agaataaaaa atatggaaca gaattagacg aaaattggaa cagatatgag ttgagatttc
    55381 ggcaggaaat ggcagtgagt gtagtacagg aattattgag atatagagat gtggcaggac
    55441 tggcaatgga agtattgaac agcaaaatgc gatttttaga aaagccgaca gacagtatga
    55501 caacacgaaa aagactttat ccaacttatc aagcatgggc ggaactgatg aaagacatag
    55561 gcaaggtcaa actcaccatg caaccacaga agaaaagttt acaaaaggtg tggaagtggc
    55621 tagaaaagta tgttgccccg tctttgaagt tgtttgcaga ggttgggaag atagagcaga
    55681 gagattatat cggtaatcta gtgaaaaatg gagaaatgaa tatcgcacag aagcagttgt
    55741 atgatgatta tataaaagca agaaaattag acgaaagggg gtaatcgtat agaaaaggta
    55801 ttattgaatt taaaagaggt aagtgagtat cttggaattg gagaaacaaa aacaagagaa
    55861 cttttgaggg atagaaattg tccgttttcc atgaagattg gctatcggtg gtatgcgaat
    55921 aaaaaaatat tagataaatg ggtacaagaa caatcagaga aaaaaggggg aaattattct
    55981 atttgatatg tatgtaagta agtggtatag tgtaagagat aaaatgttct ataaagatat
    56041 ttatatcata cagaaaggtg tgtgatataa attgggtaag agtttaaaag gaaaagaatt
    56101 aggtgcagga ctgtatcaaa gaaaagacgg aaaatattgt ggtcgtttct atgaccgctt
    56161 tggtattaga cgttatgtat atggaaaaac catttctgaa acaaaagaga agttaaatac
    56221 agcaatgtat gaagataaaa tggaaatgaa tgttgccgat aatactgtga cattagatga
    56281 atggtatcag aaatggttgg aaatatacaa atacaaagtg attgcaccca gtacaagagt
    56341 acaatatgag agcatttata aaaagcatat acaaacagat ttcggacaca tgaaactgaa
    56401 agatatacag cctttacaaa tcagagggaa attagtaaat cttgataaaa agggatttgg
    56461 atatgaaact cagaataaag tacgtatttt actgttagat atgtttaata aagcggttgc
    56521 ggacaacgtg gcaatgaaaa atcctgtaag gaatattaaa gttgttcgag atgaagaaaa
    56581 agaacctcgt gtactgtcaa cagaagaaca atctgccttt tttgacacct gtaaaggaac
    56641 attttacgat aatcttttta atgtggcaat atcaacagga cttcgccccg gcgaattata
    56701 tgctttagaa gctgaggact tggattttga gaaaaaggta atacatatta caaaatcgtt
    56761 atcctatcag aaattcgagg gagatacagg aaagactttt cacatgggaa aaacgaaaac
    56821 gaagtccagt tatcgtgatg tgcctatgaa tagaagatgt gaaattgcat taaagaaaca
    56881 gttattgcag aaaagagttg tttcgggtag aaatggtgca aaaacattaa aaggatttga
    56941 aaatttgatt tttacaacaa aatatgatac tcctcttaat gcacagattt atgcagatgc
    57001 tatcaaggta atcgttgagc aaatcaatct tatgcgagag gaattggaac aatttgaaac
    57061 attttcgggg cattgcttta gacatacatt tgcaacaaga tgttttgaag caggaataca
    57121 gccgaaaaca gttcagaaat atctaggtca tgctacatta caaatgacaa tggatttata
    57181 cacccatgtg ctagaaaacc atttatcaga tgaaatggat aagttagata gcaggctgga
    57241 aatgattgaa ctttcaagtg atgatttagc agagcaacgt tttgaacggg aatataggaa
    57301 acagaacgaa gttttgtcct ctgataagtt aatacgcata ggataaaagg gagtataata
    57361 ggagtaacag aaaatgctat gggagtacaa agtgcttgaa aatggcttaa ataaaggaaa
    57421 aatcaagata tgatttgtac tccctagttg ttttattata ttattcatac ttaggatgcc
    57481 taaagatgtt aatgaaaaag taaaatctaa aggtaaaaaa gagaaagcat ctgatacaat
    57541 ttctccttcc gtatggggtt atacattaaa agaagctaaa aaaattaaat atttttggat
    57601 tatgacgatt ggatttatat ttgttggtat atatgtttcg tcattatctg tacaatatcc
    57661 aacttatctt agaaattatc taaatcctat tctaatagga acagtaggct cgacatttgc
    57721 tttatttgct ctcattggta atttatttgg aggattattg tttgataaat tcggtcaaat
    57781 aaagccactt attatatctt ttgtattggt tcttatagca actttatcat tactattggt
    57841 agataaatct tctgcttttg catttgtatt tgccattttg aaaggtcttt ctgtatttgc
    57901 ttatatgatt ggtcctgctt atttaactgg cactttcttt ggtcaaaagg aatttggtag
    57961 catatatggt atcgtacaat taatttttgc agtgggattt gcattaggtt caacattatt
    58021 tggattacta gttgataatt ttggatatag attttcttgg tctattataa ttttatcagt
    58081 tataattgcc tatactttac ttattataac ttctatagga atgaaaaaat tgaataaaga
    58141 aagactagat aaactgatgc aataatcgat ttttagatat ataaatatta tatgaaaaag
    58201 atggagcttt taatcataaa taaaactcca tctttttata ttacaatata gctaattttc
    58261 tcttattttt aactttacta tctatatcct catccttaac tatagtaaat gccttagttg
    58321 gacaaacatt tacacatgca ggtccttctg gtgattctat acaaaaatca cacttatttg
    58381 ctgtcattct ttctctaaaa caaagctttc cttcatctac atcttttaat gtaactatgt
    58441 ctattgcacc tataggacat gctaacatac aagtcttaca tcctatacaa ttttcttcat
    58501 ttatttttat tgtgttccca accctaacta taccaccatt tggacatgcc tttgcacaag
    58561 gagcatcttc acaatgtcta cactgtattg gagcacttac ttcttttgtc tttatgacag
    58621 aaagttttgg attaaaattt atttcatctg gattttggta aaaaatatct tcatctgaat
    58681 gtgcaactac acatcctatc atacaagttc tacatcctat gcatttatca gggtctgcta
    58741 taacaaaata gttcatcact tagccacttc ctttcctata caatatgtag tgtgtaatag
    58801 atgatgagat ttttctccta atggttctac caaatattca tcatatagtt ttttaatatc
    58861 agggttctca tgagattttc taattgctaa atgttcatca tgcacatacg ttgcttttgt
    58921 tctattttca taggccaatt ccttatattc ttctagtaaa atttttggct gacctccacc
    58981 gcttacacac ccaacaggac aagtcataac ttcaataaaa tctacatcta attttccttt
    59041 ttccaagtct tcaagcactg gtattacatt ttttaatcca cttactactc caactcttaa
    59101 gtctaagtct cctattttaa tagttgactt tctaaaacca ttttctcctc ttacttgttt
    59161 tacttctaca tcaggaatac tttctccagt tataagctca tatcctgttc ttatagcagc
    59221 ttccataact ccaccagtaa caccaaagat agttccagct ccactataac tacctaaagg
    59281 gctatcaaat ttttcttctc ttaaattttt gaaatcaatt cccatgtctt ttattaaata
    59341 cgctagttct ctagtagtta acactacatc tacatctcta tatccactag aatccatctc
    59401 ttctctatca cattcatatt ttttacatgt acatggcatt atagaaacac taaatatctt
    59461 tgatgcatct acattattta tctctgcacc ataagtttta aatattgcac cacccatctg
    59521 ctgaggtgat ttacaagaag ataaatgatt agttaattta ggataatttt tttccatgaa
    59581 ttttacccaa gctggacaac aagatgtaaa cattggaaga gttccacctt ctgtcaccct
    59641 tttaattaac tcactacctt cttccattat agttaaatct gctgcaaaat tagtatcgta
    59701 aactctatca aaatttaaag ctctaagtgc tgctgccatt ttcccagcac ctaagtatcc
    59761 taaataatat ccaaaatctt cccctaaagc aactctaact gctggtgcac actgaaccat
    59821 agtaaataca tttgggtcac ttaaagcttt tttaacctta tctatatcac atacattgta
    59881 tgctgcaaat ataggttcat ttatagactc tggtatctct ctttcttgtt ttttctcttg
    59941 caaaaactca aatccttcat ctataactga ggcataagat ttacaagttt gaacacattg
    60001 accacacata acacatctat ctaaatttat ctcttgtggc tttccctctt caccttcaat
    60061 agcatttact ggacagactt ttgaacattc tctacatcca gtacataaat ctttatctat
    60121 atttattatc ataaacgtca cctacccctg tatcctttat ttatttgtta acaataagct
    60181 aagtgcagct tgtctattct tagctttttt gtcatctatt ggagtaacaa gttttaatgc
    60241 ttcctgagga catgcactta tacaagctat tttttcactg tctttacata agtcacattt
    60301 ataagctatc tttttatttt catctaaaat tacttgttct acttctttac catcttgata
    60361 ttgtggaagt aaatctatag ctccaaaagg acatgctaac agacaagttt tacatcctat
    60421 gcacttttct tcatttacag acataatatt attttctttg attatagctt tttgtggaca
    60481 tgagtttaaa caaggagcat cttcacagtg tctacactgt attggcatac aaaaattgtc
    60541 accttttact aaataaagtc taggtataac aggtatatca actgttccta ctgtataacc
    60601 aacattatta tgctgattat gcattgtaaa acaagctact tcacaagctc tacaacctgt
    60661 acatttgttt gggtctgcta ttacaaaaga gcctatttta tttttcatat tatcccacct
    60721 ttcaatttgt atatttccaa ccctctagtt accttcatca tatatattta tatattttaa
    60781 tattttctca atactcatat ttcgtttaca ttttttgcac aaattgtatg tgttgttata
    60841 caccttatca gtatcattaa ttaatactcc gcagatttca cactttgaat attttagctc
    60901 ttctttttta gtacacatat actcattctc actttttgat aactctctgt ggatttgcat
    60961 aaatattcat ccgtcttcct cttacaaatc caataagggt tatatttaat tttttagaaa
    61021 gctctattga taaattagtc ggtgctgatt ttgatactac aataggaatt tgagtcatag
    61081 ctgcctttaa tatcatttcc aatgatattc ttccacttac agctacaatt ttatctttta
    61141 atgctatatc atttaaaaca caaaatccaa tagccttatc cattgcatta tgccttgcta
    61201 catcttcaca agtaactatt cttttatcaa aattaaatat ggatacacta tgtactccac
    61261 cggtattttt aaataactct gatgaattta aatttctatc cattatactg taaatcgtat
    61321 cataatttat ttttatattg ctctctacag gagcacatgt tatatagtct agtgaattta
    61381 aaaatataat ttgctcattt tgattttttt gcttctcatg aatagttact tttgcaaaac
    61441 gttcactctc atttatctca aattttaata agcttttttt attttctata tatccttttg
    61501 ttttcaaaaa tcctactata agctcctcta aattagatgg tgtacataaa aatgtattta
    61561 tatatttatt atttaaaata aaactaagtg gatattctgc aattatttct tcattatcta
    61621 ttgatacttc atgttcattt attttactta cttctacatt aaaagaattt aaatatttgt
    61681 gctccactag actataacta ttttcaaaaa ctttatcctt actattttgt tgtaatttag
    61741 tttttgagta tatattgttc ataaaatatt agcctttctg aattttataa atctttaatt
    61801 taataaatca ttagatattt gtagctgtca ttttatcttt caaactttta tactcttctc
    61861 ttacacattt ctctgctaat tcttggtctt caagtttttc aagcttaaca gcacaatatt
    61921 tatactctgg tgttttagat atagggtcta aatttgctat tgtaagttca ttacaagccc
    61981 caacccacca ctgataagtc atatatgttg caccttcctt aactctatca gtaactgttg
    62041 ctcttgttat tacacttcct cttcttgaac taattctaac taattcatca tcttcaattc
    62101 ctaatttttt agcatcatta gaatttattt gaacacgccc tggttcatct tctaatgaac
    62161 taagtgttct gcaattacca gtcattgttc tcactgaata gtgtccaact tctcttacag
    62221 tacacaaact aaatggatac tcatcatctt caacttccat aggaggtctc cattcagcag
    62281 caaacaaatt acctttacca ttaggagtag aaaacttttg accttcatat agatacatag
    62341 tacctttatc ttccatgctt tcgctcttac aaggccattg aacacaccct tgagcttcta
    62401 tcttttcata agtagcacct aagaaacttg gacataattg tctaagttca tcccatattt
    62461 ccttagtatt tttataattc ataggatatc ccattgctgt agaaatttcg cttataattt
    62521 gccaatctgg ttttacatca ccttgtggct ctatagcctt tctcatcaac tggaatcctc
    62581 tatctgcaca tgtatatact ccctcatgtt ccccccaaga agtagctgga agtataacat
    62641 cagcatgaag tgctgtctta ttcataaata tatcttgaac aatgacaaac tccaattcat
    62701 ctaaagcttc tctaacttct gatgcatctg ggtcactttg cactgggtct tctccaaata
    62761 tataataagc tttaagcttt ttctctttta gaactaaatc tggaacttga gttaaactat
    62821 aaccattatt aggagatagt tttactcccc aggctttttc aaacttttct cttatcttat
    62881 catcagttac attttgatag ccaggatata cattaggaag agctcccata tcacaagctc
    62941 cttgaacatt attttgtcca cgtacaggtc ctattccaac gctttctcta ccaaaattac
    63001 ctgtaagtag agcaattgat gcaagtccct taactacatc aacagcttga ccaaattgac
    63061 agacacccat tccataaagt atcatagctt ttttgccttt tgcatattcc ctcatagctt
    63121 ttcttataag ctcttctggg attcctgtaa tcttttcagc atatttagct gtatatggtt
    63181 taacaatttc tttatactca tcaaatcctt gtgtatgatt ttgaacaaat tctttattgt
    63241 aaagaccttc ttctattaag acatttccaa aagcatttac taaaaccatg tttgttccac
    63301 cttttatagg tagatgtata tcagcaattc ttgcagattc agttactcta gggtcagtaa
    63361 caattaattt agcaccattt tttttagctt ttactattct atttgccact attggatgtg
    63421 aatctgctcc attatatcca aatataaata aaacgtctgc attttctatc tctggtatag
    63481 aattagacat tgcaccacta cctaatgagt aagccagacc ggctacagat ggtgcatgtc
    63541 agacacgagc acaatggtca acattattag ttcctattgt agctctcata aatttttgca
    63601 ttatataatt tgcttcatta ccaggtcctc ttgcagaacc cgttcccata atagaatcag
    63661 gtccatattt ttctttaatt tcatttaatc ttgaagctgc atagtttata gcctcatccc
    63721 attcaacctc ttctagtaca ccttgttttc ttatcattgg cttttttagc ctaggtgtta
    63781 gaattttagg gtcatttagg aaatcccatc cataacgacc ttttaaacac aaactttctt
    63841 gatttgttct accattagct ggttcagctc ttaatatctt attatctttt actactagat
    63901 ataattggca tccagctcca cagtatggac aaactgttaa aatttttttc tccatacaat
    63961 tcccccctta gatttatccc ctgataagta aaatttatct taaagataat gagtgttttt
    64021 ataatatgca aaatcataaa tattttgcaa tactatctat taaattcaac aattttctca
    64081 caattccttt taaatttcaa aaaaaatatg tcataataat ctttatattt caaccattta
    64141 attaaaatat tctagttctt atgacatatt ttttaatata ctcaatatat attatttaaa
    64201 cttatttagt tttcacttaa aacaatattt ctgccaattc tatttttcat tctatagtga
    64261 gtaattacag taaatattcc acttccaatc agaatcaaat agtacataaa tccaccatat
    64321 aaaaataccg catatcccat caaaggttga gggaatactg atttaaatat agtaaaaaat
    64381 gctaattcat tagctcctac atttccaggt gttggtattg gagaaattgc catatataaa
    64441 aatgcttgta atgtaagtat atagatatag ctataacctt gtaaattaaa tgctttatat
    64501 atccagaatg aaacactaaa gtaagcactt aattgaataa aagttactat tatagttgaa
    64561 attaatactt ttttattctt tgcaaaaaaa tttattgctt tactataatc atctataaaa
    64621 ctttctatag attcaatctt attatctaaa aattttaaaa acttaatttt tgataaatgt
    64681 tttatagtaa ttctcataaa atattttatt ttttgaggat ttaaaataac taatattatc
    64741 ataattaaga caaatgaatt aatggctatc cctagaaaca ctagaggcat aatcattttc
    64801 atttgttttt ctaacatagc aaaattcatt aatacaagta ttgtacaata aaaagtaacc
    64861 actatttgga aaataataga cttattggta acaactgcac ttgccttact aagtggcatt
    64921 ttacattttt taagtacata tatctgtact ggttggcttc ctgaagcaaa aggagttatt
    64981 aaattataat aaaatcccat aatggctagc ttaaagccaa taaatctaat attaactttg
    65041 tgagtgcttt ctataattat cttcattact actccttcaa gcattatgtg acacattatt
    65101 gccaaagcac ctatgaataa aaacttctta tctaccataa ccataacatt tgatagcatt
    65161 ttaatatcca atgttttaaa cactaggtaa attgttatac ctattaacaa aaataaaaat
    65221 gtatactgta gtaaactttt tctaatactc tttagtctat ccattagaaa taaccatcct
    65281 ttgttcaaga tttatactaa atactatatt attagtatat actatgaatc ttaatatttt
    65341 ataacaaaat accttacaat tttgtcattt acaaaaaata ttaatctata tattaaattt
    65401 taatatatag attaatattt tacaaacatt ttgtagatat atataatatt ttcactaaac
    65461 agcaattatc tttattacac ccatttatac cctatccccc atacagtttc tattgtataa
    65521 atatcatatt gttttaattt gcttcgtata ttttttacat gctctgtgat agtacttata
    65581 tcactttctc catcaaaacc atataccgac tcatatattc tttcttttga aaatacttgt
    65641 cccttatttt ttgctaaaaa ttcgcatatc agatattcac ttttagtaaa attaattttt
    65701 ttaccatcaa ttaaaacttc tttacccaaa aagttaaatt gaacatttga gatagttaat
    65761 aaattctttt tttctctact ttctctcctt aaatgagcag ttattctagc ccttaattct
    65821 cccacaccaa aaggtttggt tatataatca tctgctccta taccaagacc atacataata
    65881 tcactttcca tatttttagc tgtcaaaaac agtattggac aatcaacctt atttcttata
    65941 gctttgcaca cttcaaatcc atccatctta ggcatcatta catctagtat tattagatta
    66001 aaagaattaa attcaatatc catagcattt tctatatcac taatcacctt tacttcatgt
    66061 ccatctcttt ttaatacatt ttcaatcaac tttaacacat ctaactcatc atctattacc
    66121 agtattttag acacactaac tcctccattt gcatgtttaa taacatttta atacttatac
    66181 ttaattactt ttttcaattt tatatgaatc attatactct catattatat cttacaataa
    66241 ctgattgatg ttttacaaat aaaacatttt agactcaaaa ctttatatgt aaaatattct
    66301 atacttattt tatatatgtt tatttaatta taaaaatgta tttgataatt tattattgta
    66361 atattttaaa aatgtaataa aatcaataat aagaaaacat cttataaaca tatctttaat
    66421 tatttaaatt ggaggaaaaa attatggatg aaaagataag aagcagtaac tataatgttc
    66481 catttgacta tgctagaaaa aaatttaaag aattagaccc tcatacaatt agtaatttga
    66541 gtaatatttc tttcaacaat gattcaaaca agttcatact caatttcttt gatagacaat
    66601 atattataga ctatccaagt ggagaagttt ggaatgatga tggtagtatc tgtaaaaact
    66661 tcgaacttaa aattttaata attagatact taactaatgc taaaggtata cctagaacta
    66721 ataaatatgt gacttttaag gaaataccag gaggaaatgt ttactatcca aactttttaa
    66781 acagaacgct gtctagactt tcggaagttt ttacatgtca aatagacaaa tacaagttgg
    66841 ttatggaaaa tatgggagct gaaaaagtag atatgggtga cttagcctat aagtttacat
    66901 atatgggtaa tacatctatg atatttatac tttggtttgg agatgatgaa ttccctccaa
    66961 attcaaatat attatttgat tctaatataa tttattactt caatgcagaa gatttagcag
    67021 ttgttcctga tacagctata gatgcaattt taaataaaat aaatcaatta taaatataaa
    67081 taatattatc acacaggtat gataatggtg cagattattg gactattaaa aaacctagaa
    67141 aaataatagt tatatagata aaacatatta aaaaatagtg gctttaaatt ttttaaagtc
    67201 actatttttt taaaatgatg ttcctgaaaa tatattaagt tagttattct ac
//
LOCUS       DBGJFK010000012        66146 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.012, whole genome shotgun sequence.
ACCESSION   DBGJFK010000012 DBGJFK010000000
VERSION     DBGJFK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.012"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..1253)
                     /locus_tag="ACOIAP_000989"
     CDS             complement(<1..1253)
                     /locus_tag="ACOIAP_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGZ2637898.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPTEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKILNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIKNNICSA
                     TAIRTSLKENINFFHLKNVIPEKTYNILNEKIDNGFLPMFDDLFFDTLKTIILRDMDT
                     LKDYFEVNEGIENRIYRDIFTSEFLHELQLSIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREVLKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKSTNIYNSVYYKNNKDLVKGPMD"
     gene            1707..2903
                     /locus_tag="ACOIAP_000990"
     CDS             1707..2903
                     /locus_tag="ACOIAP_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HGZ2637899.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEDALKECIDLAPLHNPANIMGIDACKAILPDVPMVAVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            2996..3520
                     /locus_tag="ACOIAP_000991"
     CDS             2996..3520
                     /locus_tag="ACOIAP_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGZ2637900.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            3545..3721
                     /gene="rpmF"
                     /locus_tag="ACOIAP_000992"
     CDS             3545..3721
                     /gene="rpmF"
                     /locus_tag="ACOIAP_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGZ2637901.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            3928..4485
                     /gene="fapR"
                     /locus_tag="ACOIAP_000993"
     CDS             3928..4485
                     /gene="fapR"
                     /locus_tag="ACOIAP_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045717 - negative regulation of fatty acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HGZ2637902.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            4496..5518
                     /gene="plsX"
                     /locus_tag="ACOIAP_000994"
     CDS             4496..5518
                     /gene="plsX"
                     /locus_tag="ACOIAP_000994"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGZ2637903.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVSLNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDIKQFISKYNKEN
                     KNNEDE"
     gene            5544..6530
                     /locus_tag="ACOIAP_000995"
     CDS             5544..6530
                     /locus_tag="ACOIAP_000995"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGZ2637904.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVSEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            6639..7568
                     /gene="fabK"
                     /locus_tag="ACOIAP_000996"
     CDS             6639..7568
                     /gene="fabK"
                     /locus_tag="ACOIAP_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGZ2637905.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            7584..8534
                     /gene="fabD"
                     /locus_tag="ACOIAP_000997"
     CDS             7584..8534
                     /gene="fabD"
                     /locus_tag="ACOIAP_000997"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGZ2637906.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAEIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPTGVGAMAAILGLDRNALESVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAIVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NMTKPKVDVVANVNADYYKNEGKELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            8534..9283
                     /gene="fabG"
                     /locus_tag="ACOIAP_000998"
     CDS             8534..9283
                     /gene="fabG"
                     /locus_tag="ACOIAP_000998"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGZ2637907.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIENMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMASYITGQVINVDGGMVMQ"
     gene            9346..9570
                     /gene="acpP"
                     /locus_tag="ACOIAP_000999"
     CDS             9346..9570
                     /gene="acpP"
                     /locus_tag="ACOIAP_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGZ2637908.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            9599..10837
                     /gene="fabF"
                     /locus_tag="ACOIAP_001000"
     CDS             9599..10837
                     /gene="fabF"
                     /locus_tag="ACOIAP_001000"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGZ2637909.1"
                     /translation="MNKRVVITGLGCVTPLGTGREEFWSNIKAGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAVVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            11056..12774
                     /locus_tag="ACOIAP_001001"
     CDS             11056..12774
                     /locus_tag="ACOIAP_001001"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2637910.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIVLFIKYDQNGLKEREIISKG
                     KYMSESLVADKSYDEAKKVVKTSFESIPAKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDAKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASILLKVGSYKTGEKLIKDSFKIDIDEGEKNGMVRLYALINLAEIYVEVGEY
                     DKAIEISSRVKDYKKFVNTDNYNDFEIMASIMQANAYIEKNNIQEAKNLLEKADYIIK
                     SDRTVHILDKDMYYYMAMGNLEYKNENYDSAIDNYKKSLDISTKRKLTQEKIKNLNKI
                     LNIYEKQGNVESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESELFEKTKKEIK
                     YYKILFTVILIAVLGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYRAKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDVVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIVDNIRVAIANKKWNEDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            12805..14805
                     /locus_tag="ACOIAP_001002"
     CDS             12805..14805
                     /locus_tag="ACOIAP_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2637911.1"
                     /translation="MKQSIAIVTDKLTKLSSFLEENIRLVLGNYIDINHYYLEVLKED
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKEKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGVINTFNKKALKILGINENPQGKKIEDIISKDLNILLGDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMIKCIELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLPKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYISVEFANNYEDGFGYTKKEFKEILRILYERRESSSGVGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            15154..15399
                     /locus_tag="ACOIAP_001003"
     CDS             15154..15399
                     /locus_tag="ACOIAP_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HGZ2637912.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGIKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            15434..16159
                     /locus_tag="ACOIAP_001004"
     CDS             15434..16159
                     /locus_tag="ACOIAP_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGZ2637913.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDVNPQLYGEETREETTFIYPEVDEFDLIAINI
                     ALGLQKPILGICRGLQILNVSLGGTLYQDNNLKEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDEKFVVGVQWHPE
                     MMVDYCNKMEKLFKYFINICSNL"
     gene            16182..17495
                     /locus_tag="ACOIAP_001005"
     CDS             16182..17495
                     /locus_tag="ACOIAP_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGZ2637914.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKAFGVASIFVY
                     MFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTTSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARVCFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            17701..18240
                     /locus_tag="ACOIAP_001006"
     CDS             17701..18240
                     /locus_tag="ACOIAP_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGZ2637915.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQNIIDFYNEVGGETHFLSFGKD
                     EYKISLKEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            18329..20314
                     /locus_tag="ACOIAP_001007"
     CDS             18329..20314
                     /locus_tag="ACOIAP_001007"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HGZ2637916.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKINDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTITLKGKTYKLKDTYLPTIDKKDPYKLTIEEKNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDRMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKKLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            20540..21508
                     /gene="spoIIIAA"
                     /locus_tag="ACOIAP_001008"
     CDS             20540..21508
                     /gene="spoIIIAA"
                     /locus_tag="ACOIAP_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HGZ2637917.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKISNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMALDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKVIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIDD
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            21498..22019
                     /locus_tag="ACOIAP_001009"
     CDS             21498..22019
                     /locus_tag="ACOIAP_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HGZ2637918.1"
                     /translation="MQIKIIIIALLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGRNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            22036..22233
                     /gene="spoIIIAC"
                     /locus_tag="ACOIAP_001010"
     CDS             22036..22233
                     /gene="spoIIIAC"
                     /locus_tag="ACOIAP_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HGZ2637919.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            22258..22635
                     /gene="spoIIIAD"
                     /locus_tag="ACOIAP_001011"
     CDS             22258..22635
                     /gene="spoIIIAD"
                     /locus_tag="ACOIAP_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HGZ2637920.1"
                     /translation="MQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVMFKL
                     NFIVDSVQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEFGGK
                     IIVMSMSFPILLSIVEMVVNIIP"
     gene            22720..23925
                     /gene="spoIIIAE"
                     /locus_tag="ACOIAP_001012"
     CDS             22720..23925
                     /gene="spoIIIAE"
                     /locus_tag="ACOIAP_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HGZ2637921.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSENKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLVGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTIYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            23984..24601
                     /locus_tag="ACOIAP_001013"
     CDS             23984..24601
                     /locus_tag="ACOIAP_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HGZ2637922.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGSYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNNAKSNSSANEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLSLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            24613..25167
                     /locus_tag="ACOIAP_001014"
     CDS             24613..25167
                     /locus_tag="ACOIAP_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HGZ2637923.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKNDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            25194..25880
                     /locus_tag="ACOIAP_001015"
     CDS             25194..25880
                     /locus_tag="ACOIAP_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HGZ2637924.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSNNVDKQDGKESADIDIVDSKTSKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNNK"
     gene            25990..26352
                     /locus_tag="ACOIAP_001016"
     CDS             25990..26352
                     /locus_tag="ACOIAP_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGZ2637925.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            26437..26943
                     /gene="nusB"
                     /locus_tag="ACOIAP_001017"
     CDS             26437..26943
                     /gene="nusB"
                     /locus_tag="ACOIAP_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGZ2637926.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDRVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            26927..27997
                     /locus_tag="ACOIAP_001018"
     CDS             26927..27997
                     /locus_tag="ACOIAP_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HGZ2637927.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVMDNSK
                     GLRQSEAVFQHVNNLGILSDRIKSFKDRFHVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     RLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNRFISVHMSGGTTEILLTSKQDSHH
                     NVCDIDLSKFAKTSIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGVKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIIKDNGDNANQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVSEVVFAGGVSASKYIFRELTMKLGKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            27994..29199
                     /gene="xseA"
                     /locus_tag="ACOIAP_001019"
     CDS             27994..29199
                     /gene="xseA"
                     /locus_tag="ACOIAP_001019"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGZ2637928.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGIKVIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIRRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RLSKSLTNQIELDQYRLEAVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLRLE
                     DEKLVKIGALLHNLSPLATMDRGYSIAQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IEKIENKEV"
     gene            29201..29416
                     /gene="xseB"
                     /locus_tag="ACOIAP_001020"
     CDS             29201..29416
                     /gene="xseB"
                     /locus_tag="ACOIAP_001020"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGZ2637929.1"
                     /translation="MNLTYEEAYKRLESILNELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            29419..30306
                     /locus_tag="ACOIAP_001021"
     CDS             29419..30306
                     /locus_tag="ACOIAP_001021"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGZ2637930.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDESKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLNGLAEYIIDREY"
     gene            30336..30773
                     /locus_tag="ACOIAP_001022"
     CDS             30336..30773
                     /locus_tag="ACOIAP_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HGZ2637931.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGVVTALILM"
     gene            30807..32672
                     /gene="dxs"
                     /locus_tag="ACOIAP_001023"
     CDS             30807..32672
                     /gene="dxs"
                     /locus_tag="ACOIAP_001023"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HGZ2637932.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KESESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYINTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKDLIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSGKVKSMSTSVGEKLVDMANNNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     RELELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDNGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEDMLKVLLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNADELYDFVGLSPKSIADKIRKLFIK"
     gene            32805..33617
                     /locus_tag="ACOIAP_001024"
     CDS             32805..33617
                     /locus_tag="ACOIAP_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGZ2637933.1"
                     /translation="MKKRIDLLLVEQGHFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCNIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEIVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNDGYEFDGEIYNNKIVEVVEASHNLEK"
     gene            33637..35316
                     /gene="recN"
                     /locus_tag="ACOIAP_001025"
     CDS             33637..35316
                     /gene="recN"
                     /locus_tag="ACOIAP_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGZ2637934.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNTYLKKILEENDISIEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYRKIK
                     DRLDEILNRDERVEQLKSKLMKIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGLFTLDGVDDIEFMISFNLGEDINPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            35531..36397
                     /locus_tag="ACOIAP_001026"
     CDS             35531..36397
                     /locus_tag="ACOIAP_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637935.1"
                     /translation="MNKKDTLHLIFIIVIFILLWYVVVTVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDVDVQLSKLGENGKVFF
                     MYKEESNKWNETEMTKHGELSYVCEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFSSGIRDNREYFIEMVENSNLFNHESEKSKNKAYNNIRLEKVDIIVNEGKKD
                     TVYKAKLVESLDDGKTNNSNRNQVNYEASFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEN"
     gene            complement(36490..36969)
                     /locus_tag="ACOIAP_001027"
     CDS             complement(36490..36969)
                     /locus_tag="ACOIAP_001027"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2637936.1"
                     /translation="MAQNITLQFVEEKDLENLENVKVLFTEYSNSLNIDLCFQDFNNE
                     LKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKIGKIL
                     LEEIIEEAKKIGYTHMRLDTLPSMKSAQGLYKKFGFYDIEPYTYNPIEGARYMELKL"
     gene            complement(37042..37482)
                     /locus_tag="ACOIAP_001028"
     CDS             complement(37042..37482)
                     /locus_tag="ACOIAP_001028"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2637937.1"
                     /translation="MKLNVRIADINNWRDLVNLSVDKSQLDYIESNALSIAESKFITA
                     WIPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGRGYGKASLDFLVNHLKKEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            37643..38701
                     /locus_tag="ACOIAP_001029"
     CDS             37643..38701
                     /locus_tag="ACOIAP_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="HGZ2637938.1"
                     /translation="MNKINKNFKKIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNQDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNRYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            38843..39667
                     /gene="spo0A"
                     /locus_tag="ACOIAP_001030"
     CDS             38843..39667
                     /gene="spo0A"
                     /locus_tag="ACOIAP_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA];
                     GO_process: GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HGZ2637939.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            40079..41200
                     /gene="steA"
                     /locus_tag="ACOIAP_001031"
     CDS             40079..41200
                     /gene="steA"
                     /locus_tag="ACOIAP_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytokinetic ring protein SteA"
                     /protein_id="HGZ2637940.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSYQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            41218..42093
                     /locus_tag="ACOIAP_001032"
     CDS             41218..42093
                     /locus_tag="ACOIAP_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HGZ2637941.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLANVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIVLKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNSLGNTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            42117..42809
                     /locus_tag="ACOIAP_001033"
     CDS             42117..42809
                     /locus_tag="ACOIAP_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGZ2637942.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDINQINEIIVVDDGSIDN
                     TAKAVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADVIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            42817..43641
                     /locus_tag="ACOIAP_001034"
     CDS             42817..43641
                     /locus_tag="ACOIAP_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HGZ2637943.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            43646..44713
                     /locus_tag="ACOIAP_001035"
     CDS             43646..44713
                     /locus_tag="ACOIAP_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HGZ2637944.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPNISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFVASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADVVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLNKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            44715..45251
                     /locus_tag="ACOIAP_001036"
     CDS             44715..45251
                     /locus_tag="ACOIAP_001036"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGZ2637945.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     VKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVHEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            45319..45924
                     /locus_tag="ACOIAP_001037"
     CDS             45319..45924
                     /locus_tag="ACOIAP_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HGZ2637946.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPSSSNN
                     ILNNINPAVEYYNLNISIKDAVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILTLISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTVSIGIIKFLAK"
     gene            45936..46850
                     /locus_tag="ACOIAP_001038"
     CDS             45936..46850
                     /locus_tag="ACOIAP_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2637947.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLI
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKSQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDIELQKAEAK"
     gene            46892..48064
                     /locus_tag="ACOIAP_001039"
     CDS             46892..48064
                     /locus_tag="ACOIAP_001039"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGZ2637948.1"
                     /translation="MSRVIWIVIDSVGIGALPDAENFGDSKDVSTLGNIFREYPDINI
                     PNMRKLGIGNIDGVDFFESIKTPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIDEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKKDLF"
     gene            48111..48923
                     /locus_tag="ACOIAP_001040"
     CDS             48111..48923
                     /locus_tag="ACOIAP_001040"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGZ2637949.1"
                     /translation="MFEKIAQSSKFINAKINIKPKIGLILGSGLGDLANDIEDSVTIK
                     YSEIPNFPISTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEVLIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRLGDRFPDMSDAYSS
                     RYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQSLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            49126..50451
                     /locus_tag="ACOIAP_001041"
     CDS             49126..50451
                     /locus_tag="ACOIAP_001041"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGZ2637950.1"
                     /translation="MRMYDIIRKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFINSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLIASSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFDLA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAYDFDDGVEKIRESIKSGDAIHKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYINKIKAEDVGVSAMILGAGRETKDDVLDLSVGIILEKKVGDYINEGE
                     VLAYMYYNDEQKLSLAKDRFIDSYSIVDSKVEKNKLIYGIVTKEGIKKF"
     gene            50664..51743
                     /gene="mltG"
                     /locus_tag="ACOIAP_001042"
     CDS             50664..51743
                     /gene="mltG"
                     /locus_tag="ACOIAP_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGZ2637951.1"
                     /translation="MNFKENRLKIAALIIVILIILAGIFVSMQIGPYNKNNKKDVIID
                     IPNGASIGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKKLNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPDKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            51915..52589
                     /locus_tag="ACOIAP_001043"
     CDS             51915..52589
                     /locus_tag="ACOIAP_001043"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGZ2637952.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKIQKPKRVLEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFENNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLIPIGDGVALSYKESKRG
                     DVDGIK"
     gene            52576..53823
                     /locus_tag="ACOIAP_001044"
     CDS             52576..53823
                     /locus_tag="ACOIAP_001044"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGZ2637953.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YKDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEAMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            53895..55559
                     /locus_tag="ACOIAP_001045"
     CDS             53895..55559
                     /locus_tag="ACOIAP_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HGZ2637954.1"
                     /translation="MSKKKTPFLKKVGKRSWCVFTIILIIYSALIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKYQVLVVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQAKNIDKNMKKELEKNGIMIEEKTMRYSKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTID
                     NKDKDRHLKTTIDYNIQRKLEQILNKEENPTAAIISEVSTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIMANNGTFKPLYLYKSLVDNDMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIQ"
     gene            complement(55657..55941)
                     /locus_tag="ACOIAP_001046"
     CDS             complement(55657..55941)
                     /locus_tag="ACOIAP_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2637955.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(55967..57481)
                     /locus_tag="ACOIAP_001047"
     CDS             complement(55967..57481)
                     /locus_tag="ACOIAP_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2637956.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQSLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADIVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHNYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKTSDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELSKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNAKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHED"
     gene            57663..58475
                     /locus_tag="ACOIAP_001048"
     CDS             57663..58475
                     /locus_tag="ACOIAP_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FxLYD domain-containing protein"
                     /protein_id="HGZ2637957.1"
                     /translation="MCNFKKILGLFMIIMLSVSMVACSSGGDSKDESKGKDKQFIEDL
                     GKGLKKRWDLASKEEAGTLNLEQNEAYEKFVEVEMDAVSKYKDAEFDSPELGKLAKDY
                     IKALEDSKEAIKYYSNDQLKFSELWEKPYNERSTILLTLVDKFGLKVDEKEFKVLKDN
                     AQIVNEENDLKEKVNAMAKGIKFEKVKDEYDWKTYQATVENTSDLDLQDFYLDINLID
                     KDGVIIETQTSTSVNGTWKKGQKVRLEFSTDKDFEKIEWTPHYSANNYSITE"
     gene            58515..59960
                     /locus_tag="ACOIAP_001049"
     CDS             58515..59960
                     /locus_tag="ACOIAP_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HGZ2637958.1"
                     /translation="MKIKKLLTIGLSLSMFIASCHISANALDKIESIKGADKYETTGI
                     IADKQNYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVREKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVNDTNSTR
                     LGGTDRYDTNKKIINKFYGGVKEFYIASGTDLVYALVGSTVAKNNAIVLVNNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGRQYTVEDAANAVKKLLGVKKFYYN
                     ENYPEDEDVIFLLDENFEFSGKQFYAFGYVTENSEGDVRYCVEKNDMSKVYTYNVSGV
                     MQVCNPDDYKKKEMISEEKAKQLALEECARKHKVGVDLLKVNIAYIDDFDDIKVYAVR
                     IDSKPHPNQTYGWYFIDVYSGYAYKDVWNNI"
     gene            60098..60256
                     /locus_tag="ACOIAP_001050"
     CDS             60098..60256
                     /locus_tag="ACOIAP_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637959.1"
                     /translation="MDNFLLSILASILASYIVYLISKLFRKRKKPLKAGTKSGWELDF
                     KIKFHKFK"
     repeat_region   60543..61169
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=60543..60571
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(61247..61381)
                     /locus_tag="ACOIAP_001051"
     CDS             complement(61247..61381)
                     /locus_tag="ACOIAP_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2637960.1"
                     /translation="MFEKTNINTSVMNIIESDERPIRDDELIIFAKIFGVSINYILGL
                     "
     gene            61593..61811
                     /locus_tag="ACOIAP_001052"
     CDS             61593..61811
                     /locus_tag="ACOIAP_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637961.1"
                     /translation="MKILQQFKPYKYDKEKNIEYDEKIIANQNTEVYIVYPRISDEEN
                     RRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(61976..62164)
                     /locus_tag="ACOIAP_001053"
     CDS             complement(61976..62164)
                     /locus_tag="ACOIAP_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2637962.1"
                     /translation="MIGFKKRDTKYLLKIVARAHGISVAEAIVEMQTTINNARNNPDP
                     EKQAEFIISLNTIFTKNL"
     gene            complement(62622..63281)
                     /locus_tag="ACOIAP_001054"
     CDS             complement(62622..63281)
                     /locus_tag="ACOIAP_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4386 family protein"
                     /protein_id="HGZ2637963.1"
                     /translation="MNIVVGVLSILSAFCIAGSMIGLMFSFGYPKIIRENPIIILKRM
                     QNKKTMISLLFYLFGIGGFMVVQASIALRFIEQSKGEFIWSNFAYINGIIYGVLLFVG
                     ILRYTKTFPMLSNQMINKQITEKEAGQLYKVLNTYIGETMTEHVAFVFLSFMIFCNSM
                     SLLSINYVANWIGLLGIIIAIGLFIGNLEFLGIKKLFIVNRVFSSLSAFWLLLLGICI
                     I"
     gene            complement(63337..63774)
                     /locus_tag="ACOIAP_001055"
     CDS             complement(63337..63774)
                     /locus_tag="ACOIAP_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGZ2637964.1"
                     /translation="MEEHEIFNTFVQILNWASERNKNSKSYGTDDKLYIAEIHTLVMI
                     GKMPGILQKELCKEVGVTKGRMSVIIAHLQEKNLIEMRREQGNGCTIPIYLTTLGEQI
                     YHNHNEQEMNMKIQIYQVLSKCSQEEIEKFNGILRDILEILRQ"
     gene            complement(63915..64091)
                     /locus_tag="ACOIAP_001056"
     CDS             complement(63915..64091)
                     /locus_tag="ACOIAP_001056"
                     /inference="COORDINATES: protein motif:HMM:NF024056.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2637965.1"
                     /translation="MEIMFKKKENEKKVIKQKNSRTMKIGLSVKFIDNQTKVTQISQF
                     ELRIHKDSNWKMLK"
     gene            complement(64098..64295)
                     /locus_tag="ACOIAP_001057"
                     /pseudo
     CDS             complement(64098..64295)
                     /locus_tag="ACOIAP_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
     gene            64798..65307
                     /gene="vanZ1"
                     /locus_tag="ACOIAP_001058"
     CDS             64798..65307
                     /gene="vanZ1"
                     /locus_tag="ACOIAP_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HGZ2637966.1"
                     /translation="MKSKKYNITKGLFIVYIIILTWIILFKLQFDVSSIETMNLRSIN
                     LVPFAGSLIINNKVDISEIILNVAIFIPFGIYICMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINILAFIVTIIVVLF
                     LGLVIFANL"
     gene            complement(65416..65610)
                     /locus_tag="ACOIAP_001059"
     CDS             complement(65416..65610)
                     /locus_tag="ACOIAP_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HGZ2637967.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
BASE COUNT        26274 a         6955 c        11857 g        21060 t
ORIGIN      
        1 aaatccatag ggccttttac taaatcttta ttgtttttat aatatactga attatatata
       61 tttgtagatt ttatatcata acttatgagt gttttaaaaa tcgtatcatc taatgaaaat
      121 gatatatttg aaaatttgtt tattattttt atttcagatt tattttttat ctcttttagt
      181 acttctcttc ctttgtcatt aaaagcaagt attcttatat aaggtatagt atctatattt
      241 tttataagtt gcatgtcgct tttttttata cccaacaata tattatttag agttcgtttg
      301 attttggtta aagtgtatcg cttggattta atcgataatt gtagttcatg taaaaattca
      361 gacgtaaaaa tatccctgta gattctgttt tctatgcctt catttacttc aaaataatct
      421 tttaaagtgt ccatatctct aagtataatt gtttttaaag tatcaaagaa caagtcatca
      481 aacataggta aaaaaccatt atctattttt tcatttaaga tattataagt tttttctgga
      541 ataacatttt ttaaatgaaa aaagtttata ttttctttaa gtgaagttct tatagcagta
      601 gcagaacaaa tattattctt aatttcttca gaattatatt ctgattgaac cctggatata
      661 gtaaatggtt ttatactact gtttaaatgg atgaggtttt ttatatattc tatacccagt
      721 atgttgtttg atgaatttaa tatctttgat aattgttcct ttgaataatt ttgtataaaa
      781 ttattttttt tgtcttgatg tatataatca aaaagtgcat tagctctagc cgttggaaat
      841 aacagaccat catctaaata tttttttaag agtaacttaa attcagttgg ttcatttgct
      901 aaaatttcag ctatattata aagaatttct gtatttcctt cttcactgcc aaaacatata
      961 gaatttatgc agtttagtga atttaaaatt gttatagcac catgagaaaa aatttcagca
     1021 ctttggcaag caaataaagt tggtaattct ataactaagt cgacaccatt ttcgacagca
     1081 atttttgctc tagtgtattt atcaaataaa gctggttcgc ctctttgtag aaaatttcca
     1141 ctcattattg ctacagtatg tgttgcattt gtcttttcta tagatttaga taaatgatat
     1201 atgtgtccat tatgaaatgg gttatattca actattaatc caagtatgtt cataaaatac
     1261 tccttttatc tttagttatt ttatatatat cacaatttat tataatatga ataaaatttg
     1321 aaattttaat tataaaatta aaaaaattta taaaaatgta gaaatgttac ctacataaaa
     1381 aattagttaa aagttattaa aataacttta ttaggtcttt atattatatt attataacaa
     1441 atgggaaaga ataatctaca ttaagttaac ttgttaatat attattagag aaatacacaa
     1501 tttaccatac tagaaatatg atataatata aaaaaaaagt atatactttt atattaaaag
     1561 gtgatatatt atttatgaaa atcgtttaat gtatacaata atatatctat gacaaaataa
     1621 taaaagatag agttttattt agacatttat tacaaatcaa aatttattac atattattta
     1681 taaaaaaatc taaggaggaa ataataatga aaatattagt attaaactgt gggagttctt
     1741 cattaaaata tcaattaata gatatgaata atgaagaagt tttatgtata ggattggttg
     1801 agagaatagg aatagaaggt tctatattaa aacatgaaaa agcaggtaga gatgataaat
     1861 acgttgttga acagccaatg aaggaccaca aagatgcaat agcattagtt ttagaggctg
     1921 ttgctcatcc ggaatttggt gcagttaaag agatgaaaga aatagatgca gtaggacata
     1981 gagttgtaca tgctggagaa aaatttgcaa cttcagtagt aataactcca gaagtagaag
     2041 atgctttaaa agaatgtata gatttagctc cacttcataa tccagcaaac ataatgggaa
     2101 tagatgcttg taaagctata cttccagatg taccaatggt agctgtattt gatactgctt
     2161 tccatcaaac aatgcctaaa tcttcatact tatatggttt acctcatgag ttatatacta
     2221 aatatggggt aagaagatat ggattccatg gaacttctca caattatgta tctcaaagag
     2281 cagcagagat attaggaaaa gatataaaag atttaaaaat agtaacttgc cacttaggaa
     2341 atggtgcttc tatagctgct gttgatggtg gaaaatgtgt agatacatct atgggattca
     2401 ctccattaga agggttaata atgggaacta gatgtggaga tatagaccca gctatattac
     2461 ctttcttaat gagaaaagaa ggtttagatg ctgatggatt ggataaatta atgaataaag
     2521 aatctggagt atatggaatg actggaattt ctagtgactt cagagatata gaagatgcag
     2581 ctaaaaatgg agacgaaaga gctcaagcga cattagaagc ttatgttaaa aaagtacaaa
     2641 aatatatagg agcttatgct gctgaaatga atggattgga tgtcgtagta tttactgcag
     2701 gcgttggtga aaatggaaaa gctataagag cagatattgc ttctaacatg gagtttttag
     2761 gaatgaaatt agataaagaa gctaatgatg ttagaggaaa ggaaacagta atatctactg
     2821 ctgattctaa agtaaaaatg cttttaatac caactaatga agaattaatg atagctagag
     2881 atacattaag attggtaaaa taattaaatt aaacctatgc ctatcaagta aaaatacttg
     2941 acaaacaaat gctagatttg tataataaat ttggtgatat gttgaggtga acttaatgaa
     3001 agttagcata gaaaaaataa atagaaaaga aactgacaaa atagacttga atttttgtga
     3061 aaaaattgat actattagtt attgtgatga gatttacaaa ttagtatcac ctgtaaattt
     3121 aaaagggaaa gtgtcaaaga ctaataaagg tttgtatcta gatatagatg tcaattttac
     3181 aattgttgac aattgttcaa gatgtcttaa agaagtagaa ataccactag agtattctat
     3241 acaaggtttt ttagtaaaag aagaagatta tgatgaagat gagtttgagg aatttgatcc
     3301 ttttatattc gatggtgaag aaatcgacct tattgatata atagaacaga cattagattt
     3361 taatgtacct cataaagttc tttgtagtga aaactgtaaa ggtctttgtc aagtatgcgg
     3421 ggcaaactta aatgaagaag agtgttcttg cagtgaaatt acaaacgatg aggaatacat
     3481 agatcctcgt tttgctaaat taaaagattt atttaattaa attttgacta aggaggtggc
     3541 gtaaatggca gtaccaaagc gtaaaacgtc taaatcaaac acaaaaatga gaagagcagc
     3601 taactcaaag atggaagcaa caggatttgt aagttgccca caatgtcatg agccaaaatt
     3661 accacataga gtgtgtccag actgtggata ttataaaggt aaagaagttg tgtctaagta
     3721 atagcttcta aaaagcatgt agagtatact ctacatgttt tttttgtaca tataaaaaaa
     3781 gaagatgatt tactagagaa aataagtgga ttttatgcat attaaaaaat agaaaaataa
     3841 taatataagt attgaaaatt tttgtgtgtt actatatact actattagta gctggtacta
     3901 attacagcta taaaatttgg agggaacatg aaaaagaaaa gtaaagccca aagacaaaaa
     3961 gagcttatag atatgctaaa gacagatcct ttttatactg atgaagaatt atcaagtctg
     4021 tttgatgtaa gtatacagac cataagatta gatagaatga gtctaaacat accagagcta
     4081 agagaaagag tcaaatcaat agcagaaact cagagttcaa aagtaaagac tttaggagta
     4141 aaggaaatta caggagaaat cattgattta tctgtagggc gattaggtat atctatgtta
     4201 gaagttacac aggacatgat ttactctaag actaatactt taaaagatac gtatattttt
     4261 tctctagcag attcattggc aatggctata atagatgcac ctaaggttat tatgagagtt
     4321 gcaaatgtaa agagttttaa gttgatagaa caacaagata ggcttatagc aaaagcagaa
     4381 gtgtatagaa atatagataa aaagcattat gtaaaagttg ttatcaataa taaagcccaa
     4441 gagcaaatat ttagaggaaa gtttatcttt gaagaattag attaggaggg aaattatgaa
     4501 aatagtaatt gatggaatgg gtggagataa tgcacctaaa tctaatgtag aaggcgcagt
     4561 aaatgctata aaagaatatc aagttgattt aataatcaca ggagataaag atttacttga
     4621 aaaggaattt tcaaattatg aatttgatag aaataaatta gagatagttc atactactga
     4681 gattatagaa aatgaagata aaccagtaaa ggctataaga agtaaaaaag attcgtctat
     4741 ggtagtatca ttaaatcttg taaaagaagg aaaggcagat gctataatat cagctggaaa
     4801 tacaggagcc ttacttgctg gtggattatt tgttgttggt agaataaaag gaattgatag
     4861 accttgctta tgttcagcaa taccaaatgt aaagcgagga atgacactta tagcagactg
     4921 tggcgcaaat gcagattgta aacctaagaa tctagttgaa tttgcagcta tgagtaatat
     4981 ttattcaaga aaagttttag gtcttgaaaa tcctaaggta gcattagcaa atgttggact
     5041 agaagaaggt aaaggcaatg atttagtcaa aaggtcatat gaagaaatta aaaaattaga
     5101 tttaaatttt ataggtaatg tagaagctag agaagttata aatgcataca cagatataat
     5161 catatgtgat ggatttacag gtaatatatt acttaaatct gctgaaggag tagctctttc
     5221 agttatgagt cttataaagg aaacttttat ggccagtaca aaaagtaaaa taggagcatt
     5281 acttataaag gatgatttaa gaaaattaaa aagttttata gattattctg agtatggggg
     5341 agctccactt ttaggtctaa atggaggcgt tataaaagct catggtagtt ctgatgctaa
     5401 agctataaaa aatgctataa atcaaggaat aaaattttca aagggaaaag tcgttgaaga
     5461 tattaagcaa tttataagca aatacaataa agaaaataaa aataacgaag atgaataaac
     5521 tcgttttgga ggtttaatat ataatgaata caaaggctgg aatattagga gtaggaagtt
     5581 atctacctga gcaatcatat gataattttc acttcgagaa aataatggat acatcagatg
     5641 agtggataag tactaggact ggtattaagg aaagaagatt tgccaaagag tctgaagcaa
     5701 cttctgactt agcatctaaa gctgccttaa aagctataga atgtgcaaag ttaaacgtag
     5761 aggatataga gctaattata ttagcaacaa ttactcctga tatgtctttg ccttcaactg
     5821 catgtatagt acaagatgca ataggagcag taaatgctac tgcatttgat atatcagcag
     5881 cttgttctgg atttgtatat ggagtaacta ttgcaaagca atttgtggaa acaggttgct
     5941 ataaaaatgt gcttgtaata ggggcagaaa cttgttctaa gtttttaaat tatgatgata
     6001 gaacaacagc agtattattt ggagatggag ctggagcagc tgttattggt cctgtaagtg
     6061 aaggtggaat actgtctaca catatgggct ctgatggtaa aggaaaagat tgtttaaaag
     6121 tacctgctgg aggttcaaga cttaaggcaa gtaaagagac tgtagaagct aatctacata
     6181 caatagaaat ggcaggtagt gatgtattta aatttgcagt tagaaagatg gcagaaactt
     6241 ctttaagagc tcttgaaaaa gcaaatttaa atacaactga tatagactat ttagtgccac
     6301 atcaggctaa tataagaatc atacaagctt cctctaagag attagagctt gatatgaaaa
     6361 aagtttatgt gaatatagac aaatatggaa atatgtctgc tgcatctatc ccagtagcgt
     6421 tagatgaagc ttatagagaa ggtaaaatta aaaagggtga taatgtagtt ttagttggct
     6481 ttggtggagg tctaacttgg ggggcttcag ttgtcaagtg gactttatag tataaaatat
     6541 ctaaaatgct ttaattaaca aaattaaact tatgcacaaa ataaagttga ttaataataa
     6601 aaagtttact tttatgattt caagtgaagg agaattgtat gaataaaatt tgcaaaatat
     6661 taaatataaa atacccagtt atccaagggg gaatggcatg ggtagctact gcatcattag
     6721 caagtgctgt atctaatgca ggagggcttg gcataatagc agcaggaaac gcaccaaaag
     6781 aagctataaa gaaagaaatt gttgagtgta aaaaattaac tgataagcct tttggagtaa
     6841 atgtaatgct tatgtcacca tttgttgatg atataattga tttaattata gaagaaaaag
     6901 ttcaagttat tactactggt gctggaaatc ctgcaaagta tatggataga ttaaaggaag
     6961 ctggaacaaa ggttattcct gtagtaccta caatagcttt ggcgcaaaga atggaaaaac
     7021 taggagctac agcagtaata gcagaaggta ctgaaggtgg aggacatata ggagaactta
     7081 ctactatggt cttagttcca caagttgctg atgctgtaaa catacctgta atagctgctg
     7141 gaggaattgt agatggtaga ggaattgctg catcatttgc attaggtgct agtgcagttc
     7201 aagtaggaac tagatttatt tgtagtgaag agtgttctgt acattcaaac tataaaaacc
     7261 tagtactaaa agcaaaagat agagatgcaa ttgtaacagg aagaagtact ggtcatccag
     7321 taagaacatt aaaaaataaa ttatcaaaag aatttttaaa gatggaacaa aatggagcta
     7381 ctcctgaaga attagataaa aaaggtacag gagctttaag atttgcaaca gtagatggag
     7441 acatagaaaa aggttcattt atggcaggtc aaagtgctgc tatggtaaaa gaaataacac
     7501 cttgtaagga aattatagaa gctatggtaa atcaagcaag agagattatg ccagcaatag
     7561 aactgtaaat caggaggagc aagatgggaa aagttgcact agtattccct ggtcaaggag
     7621 ctcaatatgt aggtatggcc aaggatttat atgaaaataa tactgttgct aaaagtgtaa
     7681 tagatgaggc cagtgatgct ttaaacatgg acttaaaaaa ccttatgttt aatggaaatg
     7741 aagaagagct ttctaaaact gaaaacactc aacctgctat ggttacacat agtgtagcag
     7801 tattaaaagc agtacaagct gaaatagatt taaaatataa tgcatgctta ggattatctt
     7861 taggagagta tagtgctttg gttgcagcag atgcaattga ctttaaagat gctgtatgtt
     7921 tagttaaaaa aagagggaag tttatgcagg aaacagttcc aacaggtgtt ggagctatgg
     7981 cagcaatttt aggtctagat agaaatgcac ttgaaagtgt ggttaaagat atacagggtg
     8041 gtattgtaga agtagcaaat tacaattctc ctggacaaat agttatatct ggtgaaaatg
     8101 agaagataga agaagcaata gtgaaatgta aagaagcagg agcaaaaagg gcagttaaat
     8161 taaatgtaag tggacctttt cactcatcaa tgttaaaaga agctggagta aaactggcta
     8221 gtgaattaga aaaagttaac atgactaaac ctaaagttga tgtggtggca aatgtaaatg
     8281 cagattacta taaaaatgaa ggtaaagaac tgcttataaa acaagtaagc tcatctgttc
     8341 tttgggaaga ttctatagaa aggcttttaa atgacggata tgatactttt atagaaatgg
     8401 gacctggaaa aactttaaaa gcatttatta agaagatagc ttcaaataaa aaagcaaatg
     8461 tcaatattta taatatagat ggtatagatt ctcttaatga atttgtacaa aattatagaa
     8521 atggagagat ataatgataa atcttacagg acaagtagca gttgttactg gtggctctag
     8581 gggtatagga aaagaaatag caaaaaaact agcatctttt ggagctgatg tagtaatcaa
     8641 ttatacttct aaagaagatg aggcactaaa aactaaaaat gaaatagaaa atatgggggt
     8701 aaagtgtact tctataaaat gtgatgtgtc taaatttgat gaagtgaacc aaatgataga
     8761 ttctgttgta agcgaatttg gaaaaattga tatattggtt aataatgcag gcataactaa
     8821 agatggcttg cttatgagaa tgaaagaaga agattttgat agagttatag atataaactt
     8881 aaaaggtgtc tttaattgta caaaagcagt tactaaacct atgatgaaaa agaagtatgg
     8941 aagaataata aatatgactt cagtagttgg aattatgggg aatgcagggc aaactaatta
     9001 ttgtgcatca aaagcaggtg taattggatt tacaaaagct tctgcaagag aattagcatc
     9061 aagaaacata aatataaatg cagtagcacc tgggtttata gaaacagata tgactaaagt
     9121 actaagtgat gatgtaaaag aatcaacact agcaaacata ccaaaaaaat cttatggtaa
     9181 accagaagat gtagccaatg ctgtagcatt tttagttagt gacatggcaa gttatataac
     9241 aggacaagta ataaatgtag atggtggaat ggtaatgcaa taataaaaaa taataattta
     9301 aaaagtagag aaatctatta aaataaaaat tttaggaggt acacaatgtt taataaagtt
     9361 gtagaaataa tcatagagca attaggagta gaagataaag aaataactat ggagacatca
     9421 ttaatgaagg atttagaagc agattcatta gatgcagtag aaataataat ggcacttgaa
     9481 gatgaatttg gtatagaaat accagataca gaagcagaaa actttaaatc tataggagat
     9541 atagttaagt atatagaagc taataaatag tcgagcttta aaaaagtgga ggtatccgat
     9601 gaataaaaga gtagtaataa cagggcttgg atgtgttaca ccgttgggaa cgggaagaga
     9661 agagttctgg agtaatataa aagctggagt atctggtata gataaaataa ctaattttga
     9721 tgctagtacg tatcaaactc agatagcagg agaagttaag aattttcatc cagaagaata
     9781 tataagtaaa aaagaattga agagattaga taaatttgct caatttgcag tagtatctgc
     9841 aaaattagca gttgaagatg caaatcttga tttagataaa gttgatagag aacgttttgg
     9901 tgttataata ggttctggaa taggtggagt tgaagctata gaaactcaac ataaaattct
     9961 tttggaaaaa ggaaataaaa gagtaagttc actttttgta cctatgatga taggaaatat
    10021 ggcagctggt caagtttcaa tatttttagg agcaaaagga cctaacacta atgtatgtac
    10081 agcttgtgca tcaggaactc attcaatagg tgatgctttt aaggtaattc aaagaggtga
    10141 tgcagacatt atggtagcag gaggttctga agctgctgta acaggtcttg cttttgctgg
    10201 attctgtaat atgaaggcta tgtcaactag aaatgatgac cctaaaactg catcaagacc
    10261 atttgataaa gacagagatg gttttgtaat gggagaagga gcaggtattg ttattttaga
    10321 agacttagaa catgctttag caagaggtgc taaaatatat gcagaagtag ttggatatgg
    10381 attaactgct gatgcatacc atatgacaac tccagctgaa aatggagagg gagcagctag
    10441 gtctatgaat atggctttga aagatggaaa tgttccacta gaggaagtcg attatataaa
    10501 tgctcatggg acttcaactt attacaatga tttatacgaa actatggcta taaaaactgt
    10561 atttggggaa aaggcatatg atttatgtgt gtcatcaaca aaatctatga cgggtcactt
    10621 attaggagca tcaggtgcaa tagaagctgt tgtttgtgct atgagtatag aagatagttt
    10681 tgttcctcca actataaaca tacaagaagt tggcgaagat ttggatttag attatgttcc
    10741 aaatcaaggt aaagaaaaaa atatcagata tgcactttca aattctttag gatttggtgg
    10801 gcataatgct acaatagtac taaaaaaata tgtataaata aatattaaat aaaaaaacaa
    10861 gtacttattt taactgtata aatttatatt ggattaaatt taaagtctcc taaattattt
    10921 taggagactt ttttattaag atttaagtct agcatatgtt gtaaatcatt ttgatatatt
    10981 gtattattat ttattaagag gttatttata tatgcaagtt ttcattctac aatatacaaa
    11041 aggaggacta aaattttgaa ttttagacta ccaaagaaaa ggttacctaa aaagataatt
    11101 tttatatgta taatacttat tagtattgtt ttatttataa agtatgacca aaatggattg
    11161 aaagaaagag aaattataag taagggaaaa tatatgtctg aaagtcttgt ggcagataag
    11221 tcatatgatg aagcaaaaaa agtggttaag acttcttttg agtctattcc agcaaaaaaa
    11281 tacaataaag tatataatga agtttgggat atgttaaaga ctatttcata tgttccagat
    11341 ggaacgaaga tagtcattga ttctttagaa aagatgagag aatcagatgc aaaattatct
    11401 gatgagtgca ggtttaatat agaaaaaaga ttagcatcag tgtatataat ggataataat
    11461 tattctaaag cagtagattt aactgtaaag tctataaaat tggctgagaa attggggaat
    11521 aattatgaaa aagcaagact agatgttgat ttggcgagca tacttttaaa ggtaggtagt
    11581 tataaaacag gagaaaaatt aataaaggat tcttttaaaa tagatattga tgaaggtgaa
    11641 aaaaatggaa tggtcagatt atatgctctt ataaatctgg cagaaatata tgtagaggta
    11701 ggagaatatg ataaggctat tgaaataagt agcagagtaa aagattataa aaaatttgta
    11761 aatacagata attacaatga ttttgagata atggcttcta taatgcaggc aaatgcttat
    11821 atagaaaaaa ataatataca agaggcaaag aatcttttag aaaaagctga ttatattata
    11881 aaatcagata gaacagttca tatattagat aaagatatgt actattatat ggcaatggga
    11941 aatttagaat ataaaaatga aaattatgat tctgcaatag ataattataa aaaaagttta
    12001 gatatatcaa ccaaaagaaa gctaacacaa gaaaaaataa aaaatttaaa taagatatta
    12061 aatatatatg aaaaacaagg aaatgtagaa tctttaaatg agtatcaaaa gatgttaata
    12121 aatgaatata aagagaacaa aagtataaga gattcagaga ctagtttcta tataattgat
    12181 aaagtatcaa atgaaagtga gctatttgaa aaaactaaaa aagaaataaa atattataaa
    12241 atattattta cagtaatttt aattgctgta ttagggtcta cttttttata caacagattg
    12301 aagtatttta aagcacaaaa tttacatgat gggcttacaa atgtttataa tagaaaaagc
    12361 tttgatatta tgtatgaaaa gtatagagct aaagatgata attttgcact tgtaatgata
    12421 gatattgata atttcaaact cataaatgat aattatggac ataaatttgg tgatgttgtt
    12481 ataaaaggga taacaaatac tatttgtgtt atgttggaac aagatgataa agtttttagg
    12541 tatggaggag aagaattttc tgtattgata agaaataaat ctggtgaaga agtagcagat
    12601 atagttgaca atataagagt tgcaattgca aataaaaaat ggaatgaaga tgtaactgtg
    12661 actataagtg caggtgtagc tcatatttcg gatagcaaag atgtactaga agaagctgat
    12721 aaaaatttat ataaagcaaa acaacttggt aggaataaag tagtatataa gtaactgtat
    12781 actatataaa taagaggtat aagtatgaaa caatcaatag ctatagtaac tgataaatta
    12841 actaaactat catctttctt agaagaaaat atacgtttgg ttttaggaaa ttatattgac
    12901 ataaaccatt attatctaga agttttgaaa gaggatgata aaatacaagg tgattttgta
    12961 ctagtaatga atgatgatag attaaacagt atgagaaaac atttagtaca agatagtaag
    13021 attatagtga taaggagaac ccttaaagaa aatgaaatat atggattatt ttcaatacca
    13081 aatggaactg aagtattggt tgtaaatgat acaaaggaaa ctaccttaga aacaataagt
    13141 ttattttata aaataggagt aaaaaattta aagtttactc catatattga aggaaaaatt
    13201 tataaaaata tagacatagc tataacgcct ggagtaaagg aaaaagtacc aagttatata
    13261 aataaagtaa tcgaccttgg taatagatat atcgatatat ctacctttat agaaataata
    13321 aatggtctta gaattgatgt taaagaaata cgtaaaaatt taatggcata ttctgagagt
    13381 ttaataagtt tagataatgg agttaaagat aattatagac aactgttttt aaaaatagaa
    13441 gaacaagatg ttatattgaa tctatcaaaa gatggtataa tatttacttc agcagatggt
    13501 gtaataaaca catttaataa aaaagcttta aaaattttag gtataaatga aaatccgcaa
    13561 ggtaaaaaaa tagaagatat catttctaaa gatttaaata ttttacttgg agacaaagaa
    13621 ataattgatg aagttgtatt tacaaataaa aaatatataa atgtaaataa aaaaagtatt
    13681 ttttctatgg ggaataaagc tggtatatat tataacttgc aagaaataac gtatataaaa
    13741 aaattagaac aaaaccttac taataaatta agagaacaag ggcagatagc aagatatacg
    13801 tttaaagata taaaaactaa aaataaaaat atgataaagt gtatagaatt ggctaaaaaa
    13861 atatctaaat cagacctttc tgtgctaata ataggagaaa gtggtactgg taaagaatta
    13921 ttatcgcaat caattcataa tgcttctaat aggagtaatc aaccgtttat agcagttaat
    13981 tgtgcagcag ttccagatag tctattagaa agtcaactgt ttggatatga aaaaggctct
    14041 tttacaggag ctttaagaga agggaaaaag gggttatttg aacttgctaa taatggaact
    14101 atatttctgg atgaaattgg agatatgcct ccattgctac agacaaagtt actaagggta
    14161 ttacaagaaa agcaggttat gcctataggt tcccataatg ttataaatat agatgttagg
    14221 gtcatagcag caacaaacaa aaacttacca aagatgatta gagaaggaaa atttagagaa
    14281 gacttgtatt atagattaaa tgtattacca atagatgtgc catcattgag gaatagaaaa
    14341 gaagatataa taacacttat gaacttcttt ttgaaaaata atataagact ttcaccagaa
    14401 gttataacta ttttagaaaa atataattgg ccaggaaata taagagagtt acaaaatgtt
    14461 gcttcttacg taagtctaat gtgtgatagt atggttttta gggatgactt accaccatat
    14521 ataagtgtag aatttgctaa taattatgaa gatggatttg gctatacaaa aaaagaattt
    14581 aaggaaatac taaggattct atatgaaaga agagagtcgt cttctggagt tggaagaggg
    14641 tttataattg aaaagcttat acaggaaggg attgagattt ctgaaagcaa agttagaaag
    14701 gtgctatctt atttaagtga atgtggatat atatcatcta aatctggtag aggtggaagt
    14761 caaataacct cagagggtat aaaactttat aataatataa attaagttaa gtatattgat
    14821 attgaaatta catattttga atttagatat ttaaataata aacttttata tttatagaaa
    14881 ttaatttata ttttgtcaca aagaatatta taatttataa ttaaatatta ataggttttt
    14941 aaaataggat tagataggta ataggttaag ttaaaataac ccattaccta tttttatttg
    15001 taggaaaagt gtctatgaaa ttaaaagtaa aaaataccac taataaaacg attgaaaaca
    15061 ctagataaat aataaataaa aataattata aattttggca catatattgc taatcataga
    15121 aataagatga caaaataata gggaggttta ataatgaaat acaaaacaac agggacttgt
    15181 gctacagaaa ttgaatttga ggtaaaagaa aataaagtta caaatgtaaa ctttataggt
    15241 ggatgtgatg gaaatttaaa agggataaaa gtattagttg aaggcatgaa tatagaagat
    15301 gtaatacaaa aattaaaagg aatagagtgt aaaacaaagc caacgtcttg tccagaccaa
    15361 ctgtctctag cattggaaaa ttatatgaat ataaaataat acataaaaca atcgattagt
    15421 taggagttta attatgaaac caataatagg gattttagga aatttaataa taatggaaaa
    15481 tggtatgttt ccaggtcttg aaaggtcata tgtaaataat gattatataa atgcagtact
    15541 aaaaggtgga ggtagtccag taatcattcc tgtaaataca gataaagaag ttataaaaaa
    15601 acagattgaa atggttgatg gagtcttaat atctggagga tgggatgtta atcctcaact
    15661 gtatggagaa gaaacaagag aagaaacaac atttatatat ccagaagtgg atgaatttga
    15721 tttaattgca ataaatatag cattagggct tcaaaaacct atattaggta tatgtagggg
    15781 actacaaatt ttaaatgtaa gtttaggagg aactttatat caagataata atcttaaaga
    15841 aggaagttat ataaaacaca cacaatcttc caaaagacat gtagctactc ataaagttga
    15901 tgttaaagaa ggaagtattt tagaaggaat attgggaaaa caattactta caaatagtta
    15961 tcatcatcaa agtgtcaacc agcttggaaa aggattaaaa gccatagcat actcaaaaga
    16021 tggtataata gaagctattg agaaagagga tgaaaaattt gtagtaggag tacagtggca
    16081 tccagaaatg atggtagact actgtaataa aatggaaaaa ctatttaaat attttataaa
    16141 tatttgttca aatttataat ataccttgga ggggattgaa catgaacgaa aagaataaaa
    16201 tgggattgat aagtattata cttttaggca ttaatgcagt agtaggagct ggagtttttc
    16261 tattaccagg agatgcaatg aaggcatttg gtgtagcaag tatatttgta tatatgtttg
    16321 atatgttatt agttttatct atggcattct gttttgctga ggttgcaggt aaattcaata
    16381 aaaatggtgc tgcctatgta tataccaaag aagcttttgg agatttttgt ggttttgaag
    16441 taggtcttat gaaatgggta ataggatgta tctcttgggg agctttaata gtaggttttc
    16501 ctacatcctt atcagcagta tgggctccag caggtgaacc acatatacaa aaaattataa
    16561 ttgtagccat gatagttgga cttacaatta taaatttatt aggtgtatct ctatcaaaaa
    16621 ttgtacaaaa tgttataact gtaggtaagc taattccatt aatattattt ataggaatag
    16681 gtatattttt tataaaagga gttaatttta ctacttcaac aatggtgcct ccaggagctg
    16741 gagctacaga gtttggagca gcagcacttt taatgtttta ttcatttaca ggatttgaat
    16801 ctatagcagt tgcagcagaa gatatggaaa atccacaaaa aaatatacca atagcaatta
    16861 taagtgtaat agtaattgca tcaataatat atatattaaa tcaagttgta tgtgttggta
    16921 tactaggaga ttcattatct agtacatcta caccagtggc agacgctgca agagtatgct
    16981 ttggaaatat gggagctgga ctggttacat ttggaacatt ggtttctgtt ggtggaattt
    17041 gtatgtgtgg cgcttttgta aatccaagaa gttgtgtagc tttagctgat gataaaatgt
    17101 taccgagaat atttgcaaga aaagataaaa aaggtacacc atatgtagca ataatagcta
    17161 ctatgttaat tactatccca atagctctat ctggaagttt tgctgaatta gcagcaataa
    17221 gtgcagttgc tagatttata caatatatac caacatcttt atcagtatta gtgtttagaa
    17281 agaaaagacc agaattagta ggtactttta aaactccttt tggagcagtg attcctctaa
    17341 ttgctgtatg tgttggaaca tggttattat tccaagcatc tatgcatcaa ttaattatgg
    17401 gattaggagc tttggcaatt ggagtaccat tatactttat aatgaagtct tataatagaa
    17461 aagtttatgg tgaaaattta aagaaaatag tttaattatg ttataacagt ttattgattt
    17521 aaagttagat attggcagaa aattaaatac aaataagtat ctataaggct atattaaaat
    17581 attattgatt ttttatttta atatagcctt atattgttaa tcagtaagtg aaaaatattg
    17641 taacaacaaa agaacaatag tattatgttt atagacaaaa acttattagg aggtaaagtt
    17701 atgccaacaa taacattaaa aaatggtgta gatgtactta ttagagaagg agtaagagaa
    17761 gatgctcaaa acattataga tttttataat gaagttggtg gagaaactca ttttctgtca
    17821 tttggaaagg atgaatataa aatatctttg aaagaacaag aaaatgctat agaatcagca
    17881 aaagcatctg ataattcggt taaactgatt gcatttatag atggtgaaat agttggtatt
    17941 gctacaattg attctaatca aaaggcaaaa ggaaagcatg ttggagtatt aggaattgtt
    18001 gtaaaggaaa aatattgggg aattggactg ggtaaaaggc ttatgttaga ccttatagaa
    18061 tggtgtaaat caaatggaat aaccaagaag ataactcttg tcactaatga agaaaattat
    18121 aatgctatag gattatacaa aaaagttgga tttgaagtag aaagcatact aaagaaagaa
    18181 tgttattata atggtgttta cactgattta ataggaatgt cacttttgtt gggaatataa
    18241 ttagtgtaca ttttatatcg aaaaaactat attaagtatg gtataattaa aaaagaatat
    18301 aacttaatat aattttggag gacgaattat gaaaaatctg tgtaaaatat cagatgatta
    18361 tttaaacagc aagcttaagt atttaaagtt attatcaaaa caatatccaa gtatatcaaa
    18421 agcaagtaca gaaataataa atttagaggc tatattaaat cttccaaagg gaacagagca
    18481 ttttataaca gatgtacatg gtgaatatga accatttgta catgtattaa aaaatggttc
    18541 tggtgtaata aagagaaaaa tagaagaatt gttttcaaat acaataagag acagcgaaaa
    18601 aaaaatgtta gcaactcttg tatattatcc tgaacaaaag ttagacctaa taattaagca
    18661 agaggaaaat atagatgatt tttatagaat aaatatttat aggcttatag aactttgtaa
    18721 atatgcttct agcaaatata ctaggtctaa agtcagaaaa ctgttaccag aaaattttaa
    18781 atacataata gaagaacttt tgcatgagca tgttaaaagt gaacataaag aagagtacta
    18841 taaaagtata gttgaaacaa tagttgatat aggaatagct aaagagttta taattgctat
    18901 ttctacagtt atacaaaaat tagttgtaga tagacttcat gtaataggag atatttatga
    18961 tagaggtcca agaccagata taattgtcga taagcttatt gaacatcatt gtgtggacat
    19021 tcaatgggga aatcatgata tcttatggat gggtgcagca tcaggtgaaa aaacttgtat
    19081 agcaaatgca cttaggatat cagctagata tgcaaattta gacattgtag aagacatata
    19141 tggaataaat ctattgcctt tagccacttt tgcgatagag atgtataaag atgacccttg
    19201 taaagaattt attccaaaga ttaatgacca aagtgtaaca acaacagaaa agtctttaat
    19261 ggcaaaaatg cacaaagcaa taagtataat tcaatttaag cttgaaggtg aagttataag
    19321 acgaagacct gagtttgaga tggaacatag acttttactt aatatgataa actatgatga
    19381 aggtacgatt actttaaaag gaaaaacata taaattaaaa gatacttatt tgcctacaat
    19441 agacaaaaaa gacccatata aattaactat agaagaaaaa aatgttattg ataaattagt
    19501 atcttcattt agaggaagtg aaaaattaca aaaacatgtt tcatttctgt tctctaaagg
    19561 aagtatatat ttaaaagcta actcaaattt actgattcat ggatgcgtac cattaaatga
    19621 agatggaagc tttatgtcta tgaatataat gggcaaagag tataaaggta aagcccttat
    19681 ggatagaatg gagtctctag caagagaagg atttttcttt aaagataagg cagaagaaaa
    19741 actgtatggc atggatatta tgtggtattt atggactggg aaatgttcat cattatttgg
    19801 taaagatgat atgactacat ttgaaagata ctttatagcg gaaaaagaga ctcataaaga
    19861 aaataagaat ccatatttta aacttagaga aaatgagatg gcttgtaaaa aattatttga
    19921 agaatttgat ttagaacttg atgaatctca tataataaat ggtcatgttc ctgtagagag
    19981 taaaaatgga gagagcccaa taaaagctaa tggtaaaatt ctcgttatag atggtggttt
    20041 ttctagagct taccaaaaaa ctactggtat agctggatac actttgatat acaattctag
    20101 aactttgcaa ttagtatcgc atgaaccatt taattctgct gaagaagcca ttgcaaatga
    20161 aagtgatatc ttatcaacaa ctgttgtagt ggaacataag gcaaagagaa aaatggtgag
    20221 agatactgat gaaggagtaa aaatacaaga ggaaatagaa gatttaaaac tacttttaat
    20281 ggcttataag aaagggctaa taaaagaaat gtagatacta tagaggcact tcataattga
    20341 agtgtctttt tgttaatact tattaaatat attatataga ttaataatag taatttataa
    20401 ccttatactt actaagtgaa tccaagataa atgggttcac tttttttatt tataaacatt
    20461 ataaaaaaat atagatgttt tggttatatt ccttgtcctt tataaataga attatataaa
    20521 caaaggagga ggacaagaaa tgaataaact ttctgatgaa ataataaact ctctttctac
    20581 aactataaga gaaaaggtag aaaaaatctc aaacaataat ctaaacatag aagaaattag
    20641 gttacgctca caaaaaccat tgatactaaa tgcaaactct aaagattatt tttacaatca
    20701 aaaaactatg gcactcgatt taaatcaaca aaactcatat gtagtaacaa gagaagatgt
    20761 agagcaaact tttcaaataa tatgtaaata ttcaatacat tcatttatgg atgacataaa
    20821 aaaaggattt ataactttga gaggaggtca tagagtagga ttagttggga aagtaatagt
    20881 agaagatgga caagtcaaaa atataaagca tatatcatct ttaaatataa gggtatcaag
    20941 agaaattatt ggatgctctg ataaaatttt aagtcatatc ataaagggaa aaaatcagat
    21001 taataatact ttgataatat caccacctca atgtggaaaa acaactttaa taagagatat
    21061 agtaagaaat ttaagtaatg gtaatgaaga ttatggattt aaaggtttaa aagtagcttt
    21121 agtagatgag cgtaatgaga tagcaggagc ttatctaggt gttccacaaa tggatgttgg
    21181 aataaggact gatataatag aaacttgccc aaaagacttg ggtattacga tgcttttaag
    21241 gtctatgtca ccaaatgtta ttgtgacaga tgaaattgga agtgaaaaag aaataaaggc
    21301 attatacaca gcattaaatg gaggtatagg attaataact actgtgcatg gagattcaat
    21361 agatgatata caaaatagaa aagaattaaa tagacttctg gataaagagt tatttaaaaa
    21421 agttataatt ctttccgcaa aaagaggagc aggaacgatt gaaaaaattt atgatttaga
    21481 agaaaagaga tggtattttg caaattaaaa taattattat agctctcttg ataggaagta
    21541 gttatttgat aggtgaacaa atatacaaaa cttatactcg tagacataaa caattgaacg
    21601 atttaataag agttttagaa attttgagga tggatttatc tttcggactt tatacattgg
    21661 aagaaatctt taatagaata ggtagaaata aagagttttg tttttggaaa tttttctatc
    21721 aaatatcaga aggacttcac aatgaacaaa gtaaaacttt ggaaataata atatcagaga
    21781 atattgatgt cttaagcaaa gaaacttatc taggcaataa agaaattgag gaactgaaaa
    21841 atctaatact tactttaggg aaaagcgata tagagtcaca acaaagaatg atagatttat
    21901 ctatagaaaa tttgaaaaaa caaacctatg agacaaagga agatataaac aaaaaaggcg
    21961 tattgtataa aaaattagtg acatttatag gtataggtat atgtattata ttgatttaat
    22021 atggggaggt tcattatgga aatatcattg atattaaaag ttgcaggtgt cggtattcta
    22081 atatcagtat tgaatatgat attggaaaaa acagatagaa aagattgggc aggtcttact
    22141 acattagcag gtgtaataat cgtattgggt atggtaataa cagaaataag tgatttgttt
    22201 aatactgtaa gaacaatgtt tcaactttac taaagaggag ggagtaattt ggaaataatg
    22261 caattaatag gaattgcaat catttcaact acactctgtt tagtaattaa aaaagataga
    22321 ccagagatag caaatttcat agcaataata actggagtaa taatactatt gtcagttatg
    22381 tttaagctaa attttatagt agatagtgta caagatttgg ctaacaaggc taacatccca
    22441 actatgtata tatcattaat aataaaatta attgggatag catacctaat ggaatttgcg
    22501 atacaacttt gtaaagattg tggggaagga aacattgctt caaaactaga atttggaggt
    22561 aaaataatag ttatgtcaat gtctttccct atacttttgt ccattgtaga aatggtggtg
    22621 aatataattc catagatgtg tatcttggaa tgactataag tatattatag agctttcgtt
    22681 gtattgaggt ttatagagtg aagagaggca tggttgctta tgaaaaaaag atttttacca
    22741 atgattatag gttttttatt tactttcttt tttgtaaata tctttgctat tatgatattt
    22801 gctaatgaag tgccaagtag tgaaaataaa gaatatggtg aaacaaaaaa tagcatagat
    22861 aaatatatag atggtcaatt agacaagctg gatataaatg aaattcaaga ctatataaat
    22921 aaagaaatag ttattaatga tgttaattta aaatcatttg taaaagattt aattagtgga
    22981 gaaaaaaata tcttagattt attcaataaa gatggtttga agatattgat gtttgatgaa
    23041 tttaaagcaa gtttaaaggt agtagcagtg attttggtat tggctctgtt atcatccatt
    23101 ttaaagagtc tggaaaattc tttttcatca ggtgcagtaa gtcaaatagc aacatatata
    23161 atatttatca caatggtatc acttacactt gttggtttta aagatgtatt gcagatttgc
    23221 tatgatgcaa tagaccatac tgtaggtctt atgcaagtta taatgccaat tttaataaca
    23281 tttttacttt taattggatt cccaataacg tcgactactt tgaatcctat tttcatagga
    23341 ggagtaacat tcataaatgt attttttaaa aattttctat ttgtatctat tactgttgca
    23401 tttggaattt taataataaa taatttatca aaaaatataa ggctaaagag atttttctcc
    23461 tttgtaaaac aaataaatta tgtttctatt ggagcaatgt ttactattta cttaggtctt
    23521 gtatctatac aaggattgta tgtaaccagt tttgataaat tcagtgtaaa aactgctaaa
    23581 tttgctatag gtaattttat tcctgttgtc gggggatttg tatccgattc tgtagatatt
    23641 ttattatctt catctcagct tataaaaaat atatttggag gaatagggct tatattactt
    23701 gttggaattt gtttacttcc agtgataaaa attttatcag taatagtagt atacaaatta
    23761 gcagcaataa ttgtagaacc tgttggagag gatggaatat ctaatttttt aaatgaagtg
    23821 gcaaatttaa tgataataat gctagcatca gtaattgcta taacagtaat gttctttgta
    23881 actgtagcta tcttgacctc gataagtgtc gtaagtcaag gataatttat atatcaatta
    23941 aaaataattc atttaatcta aagtttttag agaggaggat gctatgttag agggcataaa
    24001 ggcgtggata gttagtgttt tgataggagc atttatagta aatatagtag atatgatttt
    24061 accaagttct aagataaaac cttatgtaaa cctagtttta aattttatgt ttgtatttat
    24121 tgtaataact ccagtggtag gatttttttc aaaagatatg agtttagaag atagaatatt
    24181 gaaatctatg ggaagctaca acaaacagta tgtagatagt acaaatgctt tagcaaaaga
    24241 gactggaaat aatagtctat ctaagggata tgaggatggg ttaaaagaag tacttaaatt
    24301 aaaacttgat gaatatggtt atgatttaga agatatagag cttaatggag caaatataaa
    24361 taatataaaa ataaaagaaa agaacaataa tgcaaaaagt aatagcagtg ccaatgaaga
    24421 aaataaaaat aatagtacta aaagagagga agaaaacata aactctaatg acaaagaaaa
    24481 ttctaaacaa gtcttcaaaa aaggtacaga gtatgggttg agcctaaatg aagaaaaatt
    24541 aaaaaatgac ttaataaagg tgctggatgt ttctatagaa gatatacaaa ttgataaata
    24601 ggagttggga gaatgttgaa aaacttaaat gacaaagata agagaaaggt atattcacta
    24661 ataactatag caggaatatg tgtggtttca ttagtattat tatcttgttt tcctagtagc
    24721 aaaaatgata aacaagttgg aaaaacagag accaataaaa atgctgaaaa gcaagtcact
    24781 aaagaacaag aaaaagatga tttagaatca aaattaacag caatactatc taaaattgat
    24841 ggagcaggag atgttgatgt aatggttaca tttgaatcaa gtgaagaaat acaacctgct
    24901 tttaattcaa ataatacaac agaaacaaca gaggaaaaag atgcacaagg tggagaaaga
    24961 acagttacga cttctagtga aaataaaaca atgataactt caaattcaag tgaccctgta
    25021 gttataaaaa ctacagagcc aaagataaag ggagtgatag tggtagcaag tggagcaagt
    25081 gacccaagcg ttaaagagac actttatagt gcagtacaaa catcattaca agtagctggt
    25141 catcaagtag aaatatattc taaataaata catataaccg gggggataaa tgaatgaagt
    25201 ttaattataa gggaagagga tttgtaataa taactttaac tgcaatgtta gtggtagtag
    25261 gaacagtcaa ttatcaatta agtaagaaat ctttattaga aacatcaaaa gagtttaagg
    25321 catatgaaga agcgcagtta caaaaaaata ctgatgatag tgatagtagt aagacagagg
    25381 attctaataa tgtagataaa caagatggta aggaaagtgc tgatattgat atagttgata
    25441 gtaaaactag taaagtaaaa gaaaaggcaa ctgagacaag taaggaaata aaagctcaat
    25501 tatcatcaga gaaaaatatg aaaaaggcat cttatatttt agatatgaaa atgaatagag
    25561 aaaaacaaag aaatgagttg gttcaagatt taaatgaaat gataaataat ccatctacaa
    25621 cagaagaatc tagaaaagaa gcttctaata tgaaattaaa tatagttaaa atacaagaaa
    25681 aagagcttca aatagaaaat cttttgagta caaaaggata tgaagaagca ttagtttata
    25741 taagtgataa caaagttaat gtagttgtaa acgaagctaa attagaaaag aaagatgcag
    25801 caaaaatatt tgatttagtt gcagaacaag ccaatgtaaa gtatgaaaat attaaactta
    25861 caaataataa taataagtaa agtataaacc tcagaattaa ctgaggttat tttcttgcaa
    25921 agtagacttg tatttggtat tattatactt ataaaaatag ttccttaaaa tcaggaggta
    25981 agttttaata tggaagataa taaatttgga caagtaaaaa tatctaatga tgtaatagct
    26041 acaatagctg gtttagcagc attagaagtt gaaggcatag aaactacagc aacattaaca
    26101 gataagttgt taaaaaataa tggagtaaaa atacaaatcg aagaagagga tgttaatcta
    26161 gatgtaatgg ttacgataaa gtatggaatg tcaataccag atacagcttt taaagttcaa
    26221 gaaaatgtaa aaaatactgt tgagacaatg acaggactga aggtttctca agtaaatata
    26281 cacattcaag gaatcagctt taagaaggat aaagttgata aagaagaagc aaaagcaact
    26341 aagaaaaatt aatattagcc ctctgaaaag tcagagggtt ttttgctgat aattgatttt
    26401 atatggataa ttaaacttaa aggagaattt taattgatga aaaaagatag ggcacaaaag
    26461 agtacaacaa gagaatatat aatgaaactt atataccaaa taaatattaa taaagaagat
    26521 tttgaaactt tagaagatag ggtagataat tttttaaaag ataattcaga acatattata
    26581 aatagatata aggagcttgc acttcagtat tcaaaaaata caaatttaaa gttagaagat
    26641 actgaaattg aagatgttat agacaaaaaa tatataaata cagtatgcaa agcactaaaa
    26701 gaaaatcatg acaagataga tgagttaata aataagcatg ctaaaaactg gacagtagat
    26761 agaatgccaa aagtagatgt ttctatactt agattatctg tgtgtgaaat actttattta
    26821 gacactccta ataaagtatc aataaatgaa gcagtagaac ttgcaaaaat atattgtgat
    26881 gataaatctc ctaaatttat aaatggtata ttgggaagtg ttgttgatga aattgggaaa
    26941 taatataata attggaattg atactagctg ctatactact tctatagcag ctatctcttt
    27001 agataagaaa gttatattca atgaaaaaat aatgttagaa gtaatggata attcaaaagg
    27061 tttaaggcaa agtgaagctg tattccaaca tgtcaataat ttagggattc ttagtgatag
    27121 gataaaatct tttaaagata ggtttcatgt agaaggggtt tgctcatcaa aaaaacctag
    27181 acctgttgaa aattcatata tgcctgtatt caatgtaggt cataattttg ggagattatt
    27241 gtctagtata tatggttgta gattttatga gactactcat caagagaatc acattgaagc
    27301 aagtttatta aatagtaaat taaaaaataa taatagattt atttctgttc atatgtctgg
    27361 tggtactaca gagatacttt taacaagcaa acaagatagt catcacaatg tatgcgatat
    27421 tgatttaagt aaatttgcca aaacaagtat taaaaaagat gataaaagta agttatacaa
    27481 taattttgga tataatatag atataattgg aggaagtaaa gatattagct ttggtcaact
    27541 tatagatagg gtaggagtta agcttggata taaatttcct tcaggaaagt atttagatga
    27601 aaatgcttta aattgtaatc ttaaaataga aagtggtctg aaaacctctg taagagatgg
    27661 atatatgaat ttatctgggt tagaaaatca ggtaaataag attataaagg ataatggaga
    27721 taatgctaat caaaaagaat atatatctaa attagtatta gattcagtag ttagaaatat
    27781 gtttaaatct ttagtatatt tatgtgaaac ttataatgta agtgaagtag tatttgctgg
    27841 tggagtttct gcaagtaagt atatttttag agaattaacc atgaaattag gaaaaaagca
    27901 tatagaagct tattttacag aaccacaata ttcaactgat aatgctgttg ggtgtgctat
    27961 aataggattg aataactttt taggagaaag agtatgaaac taagagcttt agatataagt
    28021 gaagcaaatt catatattaa aagaatttta ataaatgacc caatactttc taatcttaaa
    28081 gttaaaggag agatttctaa ttttaaggtt catagtagtg gaaatgtata tttatcactt
    28141 aaagatgaaa catcaaagtt aaactgtgta atttttaaaa gtaattttaa tcgtaatcta
    28201 aaactagata atggtattaa agttatagct aatggatata tatcagttta tgaaagagat
    28261 ggtgcgtatc aattatacat taatgaaatt gaaatagagg gaatagggaa tttacacata
    28321 gaatttaata gattaaagga aaaacttaat aaagaaggat tatttgaccc taaatacaag
    28381 atacctatac ctaaaatgcc aaactcaatt ggcgttataa catctccaac aggtgctgtt
    28441 ataagagata taataaatgt gataagaaga agatatccga aagttaatat aaagctttat
    28501 ccagtaacag ttcaaggaga taaatcagct gaagaaatct gtgaagcaat tagatttttc
    28561 aatcatatga agaatgttga tacacttata gttggtagag gtgggggttc aatagaagaa
    28621 ctttggtctt ttaatgatga aatggtagca agagaggttt ttaattctca aattccgata
    28681 atatcagcag ttgggcatga aactgatttt actatttgtg attttgtatc tgatatgaga
    28741 gcaccaacac cgtcagcagc tgctgagatt gctactccat cattggatga tataaactat
    28801 aagcttggaa acataaaaag taggttgagt aagtccctta caaatcaaat agagctagac
    28861 caatatagat tagaagcagt atttaataag ataaataact atttagattc ttacacaata
    28921 aaagataaag ttatacaatt ggacaaaata tatgataaaa taatttttgg aatagaaaat
    28981 aatttaagat tagaagatga aaagttagta aaaattggag cattacttca taatttaagt
    29041 ccattagcta ctatggatag aggttatagt atagctcaaa aaaatggaaa agtaataaat
    29101 agtataaaag gattaaaaat aaaggatagt atagatatag tattaaaaga tggaaattta
    29161 gaatgtatga tagaaaaaat tgaaaataaa gaggtatagt atgaatttaa cctacgaaga
    29221 agcttataaa agactagaga gcattttaaa tgagttagaa tctaaaaatg ctagcttgga
    29281 tgaatcttta agcctatatg aagaaggtat aagcctttat aaacattgta ataagctttt
    29341 agatgatgct aaattgaaaa taagtaaatt taatcaatta ggaatagaag aagactttaa
    29401 aatagaggag gaataaaatt ggaatttaaa caatgcctaa aagaaaaagc aagttttgta
    29461 gaaaaagtac ttaaagaata tatgcctaaa gaagaagggt atcaaaaaac tgttattgaa
    29521 gctatgaact atagtttaag tgctggaggt aagagattaa gaccaatact tacattagag
    29581 gcatgtaaaa tagttggagg aaatgaagat gaagctattc cttttgctat tgcaattgaa
    29641 atgatacata catactcact aatacatgat gatttgccag ctcttgacaa tgatgattta
    29701 agaagaggaa gaccaacaaa tcataaagta tatggagaag ctatggggat tttagcagga
    29761 gatgccttgt taaactatgc ttttgaagta atgcttgcag gctcaatcaa taaagaaaat
    29821 ccagaaaagt atctaaaagc tataaatgaa attgccaaag gtgctggtat atatggaatg
    29881 ataggtggtc aagtagtaga tgtagaaagc gaaaacaaac agattgaaaa agaaaaatta
    29941 gattatatac atatgaataa aactgctgca atgatggtag gctgtatgag agcaggagct
    30001 actataggtg gagcaaattc tgaacaaatg gaagaaataa ctaaatatgc aaaaaatatc
    30061 ggattatcat tccagatagt agatgatata ctagacatag taggagatga atctaagtta
    30121 ggtaaaaagg ttggaagtga tatagaaaat cataagtcaa catacccatc tcttttaggt
    30181 ttagataaat ctaaagaaat tgcacataat ttgattgatg aagcaaagaa aagtatagaa
    30241 aaattatctg atgatgtaga ttttttaaat gggttggctg aatatataat agatagagaa
    30301 tactaaaata tacagctaaa atcgaggagg gaaaaatgga ttttttttcg gagattttta
    30361 acaatggggc tttgggaata agtctgattg cttgtttctt agcacaattt ataaaaatat
    30421 ttactggtaa ggaaaaaaga attgagttat caagaatact tatttcagga ggcatgccta
    30481 gttcccatag ctcttttgtt acaagtttag ctacagtggt aggtattgaa aaagggttta
    30541 attctactga ttttgctata attaccgtgc ttgccttaat tataatgtat gatgcagcag
    30601 gtgttagacg ggctgttggt aaacaagcta ctatattaaa tcaaatggtg gcagatatac
    30661 agcatgggaa gcatatagag cagaagaaat taaaagaatt aataggacat acaccactag
    30721 aagtttggtt tggagcttta cttggagtag taacagcttt aatattgatg taaattgaaa
    30781 atttacagaa taaaggtgag gataatatgt ataaatattt agataaagta aattctccaa
    30841 aggatataaa aaatatgagt atagaagaaa tggatttact tgcaaaggat ataagaaagt
    30901 tcttagtaaa atctgtttca aagacaggag gacacttagc ttctaatcta ggagtggttg
    30961 agttaacatt agcacttcat aaagtatttg acagccctaa agataagatt gtatgggatg
    31021 taggacatca atcttatgtt cataaaatag ttactggaag aaaagattgt tttgtatctt
    31081 taagacagtt taatggacta agtggttttc caaaggagag tgaaagtcct catgatattt
    31141 ttgacacagg gcatagcagt acatctattt ctatagctac aggtattgcc tgtgctaggg
    31201 atataaaaaa agaaaactat agtgttatat ctgtgatagg agatggttct ataacagggg
    31261 gtatggcgct tgaagcttta aatcaattgg gatatataaa taccaatatg atagtaatcc
    31321 ttaatgataa tgagatgtcc atagataaaa atgttggagg tatgtctaaa tatctgtcaa
    31381 gtattataag gaactcaaca gttgagaaaa tgacagatga agttgataaa attttaaatg
    31441 ttacacaaac aggtgaaatt ttatctaaga ctgcacatag atttaaagat aaactaatgt
    31501 atagcttttc tcctcaggac tgttcatttt ttgattcatt aggtataaga tattatggac
    31561 ctatagatgg tcataatact aaagacttaa tagatatatt gagaaaagct aaacacaaaa
    31621 aaggacctgt tcttttgcat gtaattacga aaaaaggaaa agggtacagg tttgcagaag
    31681 aacaacctga taaatatcat ggagtatcaa agtttgatat aaagacaggt gttacatctg
    31741 ggaaagtcaa gtctatgtca actagtgttg gagaaaaact tgttgatatg gctaataata
    31801 atgaaaatat agtagcaata acagctgcaa tgccatctgg tacagggcta aacctatttg
    31861 aaagtgcata tccaaaaaga tattatgatg ttggtatagc tgaacaacat gcaacaggat
    31921 ttgcagcagg tcttgcaaaa aatggtatga aaccttattt tgctgtgtac tcatcatttt
    31981 tgcaaagggc atatgaccaa gttattcacg atgtatgcat aacaaaaaag ccagttactt
    32041 ttcttataga tagagctgga ttagttggaa atgatggaga aactcatcat ggtatgtttg
    32101 atttaagtta cttaaattct attccaaata ttgtagtaat ggcgccaaaa gacacaagag
    32161 agttggaact tatgatggat ttgtcattaa aattagattg tccactagca attagatatc
    32221 caagaggaag tagttattac ctagataagg gagaatatgg agagattgta ttgggtaagt
    32281 atgaggtatt agataatggg caagatacag ttatactttg tattggaagt atggtaaaac
    32341 atgccttaga ggctaaagaa atattatcaa gagaaggaat aaatccgaca atagttaatg
    32401 ctagattctt aaagccaatt gatgaagata tgttaaaagt attattaaaa aatcataaaa
    32461 atgtagttac tatagaggat aatattgtaa ctggaggatt tggaagtaga ataaataagt
    32521 ttattataga taatgaatat aatgtaaata tacttaatat agcaatacca gaagaatttg
    32581 taaaacatgg caatgcagac gaattatatg attttgtggg attatcgcca aagagtattg
    32641 ctgataaaat aaggaaatta tttattaagt aaaaatttaa tgtagatatt gtaaattaaa
    32701 acttatataa aatataaaat ttatcaatta gaataaatat caagtgtgtt acttcaagct
    32761 actttagtta ttattaaagt agcttttaac agaaaggtaa ttgtatgaaa aaaagaatag
    32821 atttattgtt agtagaacaa gggcactttg aaagtagaga aagagccaaa aaagcaataa
    32881 tggctggatt ggtttttgtt gataatcaaa ggtgtgataa ggctggtaca gaagtaaaag
    32941 aagactgtaa tatagaagta aaaggaaatc caataccata tgttagtaga ggcggtttaa
    33001 aacttgaaaa agcaatgaaa aattttgatt tgactattga tgggaaagta tgtatggata
    33061 taggtgcatc cacaggtggc tttacagatt gtatgcttaa aaatggagca ataaaagtat
    33121 tttctataga tgttggttat ggtcaacttg catggaagtt gagacaagat gatagggttg
    33181 tgtgtatgga aagaaccaat ataagaaatg tgacaataga agatacaaag cagtttgcag
    33241 attttgcatc aattgatgta tcttttatat cgttaaagtt agttcttcca aaggcaaagg
    33301 aattagtacg tcatgatggg gaaattgtcg ctttaattaa acctcaattt gaagcaggaa
    33361 gagaaaaagt aggtaaaaaa ggagtagtta gagagaaatc tacacatata gaagttataa
    33421 aaatgatttc tgatttttca gtcgaaaatg gatttgagat tttagggtta gatttttctc
    33481 ctattaaagg tcctgaaggc aatatagaat atttaattca tttgagaaat ggaaatgatg
    33541 gatatgaatt tgatggtgaa atatacaata acaaaatagt agaagttgtt gaagcttctc
    33601 ataatttaga aaaataggtt aaaagggggc ttagatttga tcctcgaatt atatatgaaa
    33661 aattgcgcct tagttgaaga actaaggttg aatattgata aaaacttaaa tatacttaca
    33721 ggtgaaactg gttcaggaaa atctataata atagatgcac ttggactttg tttaggtgac
    33781 aaatatgata ggtctttttt aagaaaagga acagataagg gacttgttga ggctgtattt
    33841 ttttcagaca atacatatct taaaaaaata ttagaagaaa atgatataag tatagaagat
    33901 gataatttat tggtaataac cagattgata tactcagatg gtaagagtac tgctagagta
    33961 aatggaagga ctgttaaagt gtctcttctt aaagaaattg catctacact tatagatata
    34021 catggtcaac atcaaaatca agctttattt aataaagata ctcacttaaa atttctagac
    34081 ctttttggag aaaatgaatt agaagagttt aaaattgctt ataaaaatgt gtaccataag
    34141 tatagtgaag taaaaaaagc tttaaattgt ttgacagaaa ataaagatga gatgcaaatc
    34201 caacgagaaa tagatttatt aagatttcaa ataaatgaaa ttgaagctgc aaatctaaat
    34261 aagaatgaat atgaagattt attaaaacaa agagaagttt atagaaatag tgaaaagata
    34321 tataataatc taaattcgag ttatagcaag ttacataatg gcgaatataa tgttattgac
    34381 ctaataggtc ttgcatctaa agaacttaat gacatatcta aatatgacag tgttttaagt
    34441 gaatatagtg atactgtaga gagaattatg tatgagttac aagatatatc tggggagata
    34501 agaaattaca aagataatat agactttgaa ccttatgagc tagagcagat tgagcttaga
    34561 attgatgaga ttaataattt aagaagaaaa tatggagata gtatagacga tatatttgag
    34621 tattatagaa aaattaaaga tagattagat gaaatattaa atagagatga aagagttgaa
    34681 cagttaaaaa gcaaactgat gaagatagaa gaagatttaa aaataaaagc tagtaaattg
    34741 actaaagcta gaatagaagt agcaactact ttagaaaaaa tacttcttga tgaattaaaa
    34801 agcttaaata tgaaaaatgt aatgttcaag gttaattttg aaaaaggtct atttacttta
    34861 gatggagtag atgatattga atttatgata tcttttaact taggagaaga cattaatcct
    34921 atatataaag ttgcatcagg tggtgagatg tctagattta tgttagcatt taaaaccata
    34981 ttggctgata tagatgatat tgatacattg gtgtttgatg aaatagatac tgggataagt
    35041 gggatagcag cacagattgt tggtgagaaa ttgagtgata tagcaaagaa aaaacagata
    35101 atatgtataa ctcatttacc tcaaattgct gcaaatgcag acactcatta ctgtatagag
    35161 aaagatactt caaataatag gacgtttacc aatgttagta agttaaatga atctcaacga
    35221 aaaaatgaaa ttgctagact tatagcaggt aacaatataa cagaaaaaac tattgaacat
    35281 gcaagtgaaa tcattgaatt ggctaaaaag tgttagtgaa aaataagcat tttaataggt
    35341 gtaaagaatt tttatagaaa tgctttacat ctatttttta tgatgaaatt atcttaaaat
    35401 atctagttcc tatactgaag aaaagtgagt ttaaaaatgg aataaaattt gtataaattt
    35461 gtaactttga aatttctaaa tgcttaagta taatattatt tattaaggta gtagtgaggg
    35521 gaggcataaa atgaataaaa aagatacttt gcacttaatt tttataatcg taatttttat
    35581 tttattgtgg tatgttgtgg taacagtaag tgagattaat aaaaatattg aaagttgtag
    35641 taacaagcta gattatttgt cacaagagat tatgagcact aagtcggata ttagtaatac
    35701 tataaatgaa gaaatgtcaa aaagttatat aacaaaaagt attgacctaa aagtaaaaaa
    35761 aatcgagaaa aaagaatgta ttattgatgt agatgttcaa ttaagcaaac ttggagaaaa
    35821 tgggaaagta ttttttatgt acaaagaaga gagtaataaa tggaatgaaa ctgagatgac
    35881 aaaacatgga gaattatcgt atgtatgtga aataaagata aatacaggaa gtgaatatga
    35941 ctataaagta gttacaagtg gagctatatc tgaaagttct gatgtgcaaa aactgactaa
    36001 atctgattat atgcctgaac aacctatatt tagttctggg ataagagata atagagaata
    36061 ctttattgaa atggtagaaa atagtaatct ttttaatcat gagagtgaaa agtcaaaaaa
    36121 taaggcttat aataatatta gattagaaaa agtagatatt atcgtaaatg aaggaaaaaa
    36181 agatactgta tacaaagcta agttagttga aagcttagat gatggtaaaa ctaataattc
    36241 caatagaaac caagtgaatt atgaagcaag ttttcctaaa agggatattg atgacataat
    36301 ttatattaaa gctaaactta catacaataa tggagtagaa tatacaaagg atataactga
    36361 agatataact atgggattgc aagatttaga aaattaaata catatttaaa taaatattca
    36421 agtggatttg ttcaataaaa tagagtataa ataaaactgt agtagtttta tttatactct
    36481 attaaaaaat tataatttta attccatata tctagcgcct tcaattggat tataagtata
    36541 aggttctata tcataaaaac caaacttttt atataatcct tgtgcacttt tcatgcttgg
    36601 aagagtatct aacctcatgt gtgtatatcc aattttttta gcttcttcaa tgatttcttc
    36661 cagtagtatt tttcctattt ttaatcctct aaattgattt ctgacatata atctttttaa
    36721 ttcacatatt ttaccttcaa gtttttttaa agcaacacaa cctgctaaat tttcatcaac
    36781 aaatgccaat atcaatgagc ctgaaggttt tttatatttt cctggaagtg tttttaattc
    36841 attattaaag tcttgaaaac ataagtctat atttagagaa tttgaatatt cagtaaatag
    36901 aacctttacg ttttcaaggt tttctaagtc tttttcttca acaaattgta aagttatatt
    36961 ttgagccatt ttatccgcca ttatataaac atgtttatat aatgacttca cctccttgat
    37021 atatgtatat ttttcttaat atcaattaga ttttaatacc attacttttt caccgccata
    37081 gtcaagctct ccattaaact caaatccaaa atctttataa agcttaatag ccattttatt
    37141 gtcttcgaat atactaagat atagttcatc acagttatat tcctttttaa gatgatttac
    37201 aagaaaatct agtgatgctt ttccatatcc tctaccttga tattttgaat caatcataaa
    37261 tctatcaagc caaactctat catcttctaa acgaccatac atagcaaatc ctattaaaga
    37321 attttcatca tatattccaa caggtatcca agctgttata aatttagatt cagcaataga
    37381 aagtgcattg ctttctatat aatccaattg acttttatct acagacaaat taactaaatc
    37441 acgccaatta tttatgtctg caattcttac atttaatttc aagatattac cgcccttcaa
    37501 actttttgtt acaatataat actatcatat tatgtattaa aaatcactta ttaaggtttt
    37561 aagtgaactt tttgaatgaa taaattctca ggaaaaagga attataaata cataataata
    37621 cagcatagga gtagatggat atatgaacaa aataaataaa aatttcaaaa aaatttggat
    37681 aatattagga gctgtatcga tttttactat ggttataatt ttcaataaaa attgtaatgt
    37741 aaataaagag acccaaatag aagcttttac aattaagaat caagataaaa aatttgtata
    37801 tcctatggga aatataattg gagtaaaagc aaatacagac ggtgtattgg tcttaggata
    37861 tgaggaagag gatgtagact atattggagg catacaaatt ggtgataata tagtaaaaat
    37921 agataataaa aggataaaaa atagtcaaga tgtatcagag attttgaata agattaaaaa
    37981 aagtaaagtt gaagtgactt ttgagagaaa aaataggtat aaaacagaag taatagaaac
    38041 taaaaaagaa aatggcaagt ataagcttgg cttatgggta agagataaaa tatctggaat
    38101 tggaactatg actttttatg accctagtat ggaaaagttc aaagcaatcg gtcatgctat
    38161 aaaagattcg gatactaatg aactattaaa gataaagcaa ggatatatat ataagccaga
    38221 acaattgaaa atagtaaagg ctagtaatga aaaagtaggt aaaataaaag gagattttaa
    38281 tgacagcaat ttaatgggta atttctcaaa taattcagag ctaggtataa gtggtaatat
    38341 tacagaaaac cataataaag aatttaatgt agcgaataaa gaaaagcaat taatagaagt
    38401 tggaagacca caagatgtaa aaataggaga tgcagtaatt ctttttgagg ataaaaacaa
    38461 aaacataaca agctatgata taaaaataga aagtatagtg tatgataaag gaaattatag
    38521 agatatggta ataaaagtag tagatgacaa gttattggaa tacacaggag gtatcgtaca
    38581 agggatgagt ggagctccaa taatacaaaa taataaaatt attggtgcaa taactcatgt
    38641 ttttagagat aatccgaaaa aaggatatgg tatttttata gatgaaatga taaaattgta
    38701 ggtgaggcat taaaaaattt tattatttta tcaattatct aggaggaata taattttgga
    38761 gtgtcgaata tgctttagag tagataatta ggaagcaatt gtgtaaaaag tttagttttc
    38821 tgtaataaga agatgttttt taatgggggg atttttagtg gaaaaaatca aaatagtttt
    38881 agcagatgac aataaggatt tttgtcaggt attaaaagag tatttgtcta atgaagatga
    38941 tatcgatata ttaggcatag ctaaggatgg aattgaagca ttagacttag taaaaaagac
    39001 acaaccggac ttattaatac tagatgtaat aatgccacat ctagatggat taggtgtaat
    39061 tgaaaaattg aatactatgg atatacctaa aatgccaaaa ataatagtac tatcagcagt
    39121 gggtcaagat aagataactc aaagcgcaat aaatctagga gcagattact acatagtaaa
    39181 gccatttgat tttgttgtgt ttataaacag aattagagaa ctagtttcta atagagttac
    39241 acaagttgag ccaaaaccta gaccagttca agagactcaa atgactagaa gtgattttgt
    39301 taagaatgta ggaaatatag agacagaaat cacaaatata atacatgaaa taggagtacc
    39361 agctcatata aaaggctatt tatatttaag agaagcaata aaaatggtta ttgataatgt
    39421 tgagctttta ggtgcagtaa cgaaagagtt atatccaagt atagctaaaa aattcaatac
    39481 aacaccaagt agagttgaaa gagcaataag gcatgcgata gaagttgcat ggagtagagg
    39541 aaaagttgac acaataaatc aactatttgg atatacggta cacaatacta aaggaaaacc
    39601 aactaactca gaatttatag caatgattgc tgataaatta agactagagc atagtatggt
    39661 taaataaaca gacataaaaa gtaaggcttt ttaattaaag cattggctat aaatgcgcat
    39721 tacaagcagc gaaacggtat aaccagtagg gttataccgt ttcgctgttt taataaatat
    39781 aaaaaatttc cttattattt gtttactata tcaatataat aattttatta tactatggat
    39841 atagtatgtg tctttacaag ttgtgaattg acagtggttt attttttaat ataaatattg
    39901 attttggtgc aggtaaactt tgtattttta agcgtattat ggaatatgtt aaataaaaaa
    39961 atgatgaaat atagtattgt aaatgccaaa gatgcaaaac aaacttaaaa catttatttt
    40021 attgttaagt aatgctataa tataatgtga ttttaataat gatagtggag gtttaaatat
    40081 gagagtcgag gcccctataa aagtagatcg aaaaaccaaa aaacttgcta aaagagttga
    40141 aagtggggaa atagcagtta taaatcatat agacatagat gaagttgctg caaactcttt
    40201 agtagaagct aaaataaaac ttgtcataaa tgcggctcct tctataagtg ggaggtatcc
    40261 caataaaggt ccaggaatat taactgaaaa taatatacta ataattgata atgttggaga
    40321 agaattattt gaagaattaa aagaaggaga aactatagaa gttgtagatg gaaagatata
    40381 tagaaaagga aaatttttag gtgcaggaga agttttagac aagtatgagg tttcatacca
    40441 aataaaggct gcctatgaga atttagctgt agaattggat agatttatag ataatactat
    40501 agattatgct aaaaaagaaa aaggatttat acttggagaa gtagaaattc caaaagtgaa
    40561 aactaattat gctaataaac atgtattgat agttgtaaga ggtcaggact acaaagaaga
    40621 tctaagtact atgctttctt atatagaaga ggtaaagcca gtattggttg gtgttgacgg
    40681 aggagcagac gctttaattg agtttggata tactccagat gtgattgtag gggatatgga
    40741 tagtgtaagt gatgaagctt taaaaaaggc tagtgaaata gtagtacatg cttatacaga
    40801 tggaagagca ccaggtctta agagggttga ggaattaggc ttagatgcag ttgtatttcc
    40861 tgcgccagga actagtgaag atatagctat gcttatcgct tatgagtata aagctgagtt
    40921 aatagtagca gttggtacac attcaaacat gattgatttt cttgaaaaag gaagaaaagg
    40981 tatggcaagt acttttttag ttagactaaa aataggttca aagcttatag atgctaaagg
    41041 agttaatttg ttatatagaa gtaaattaaa aataaagtac atatgggcat taatagcaac
    41101 agcattattt cctgtgttgg tagttgcatc attgtcacca ggagttcaac agtttataca
    41161 actaatgcaa ttaaagttta gagtattatt acagatgtaa attttaggag gataaatatg
    41221 catattaata tgaaatatta tatagtcact ataggggcta tatttatagc tttgggtata
    41281 ggcatgttag taggttttaa tttaaataat aatcaacaat taagtgagca acaagcaaat
    41341 ataataaatg atttggatga taagtttaat attttaaaag aaaaaaatga taaacttgac
    41401 agtgacttag ccaatgtaaa tagagattat gaagaggcag ttaattttat aaataaaaat
    41461 gtagataaga ttttagctgg ctcattgaat ggtaaaagta taggaataat atcggctaat
    41521 gaaaatgatg attatacaaa aaatatagaa gacataataa ataaatctaa tggaagtatt
    41581 gcatttaata tagtgttaaa agaaaatata acaaatccag aaaagttaaa ggaaatgtca
    41641 actaaactag gtacagatgt aaaaaatgca aatgatgcag ttaattatat aatcgacact
    41701 cttaaaaaag aagatgcaag tgatatttta acatatcttc aagaactaga tgtaataaag
    41761 tttaactctc ttggaaatac atatctaaaa tatgattctg ttgtaatagc tggtggaaat
    41821 gatgcaaaag acagtacaaa acagtttgaa aaaatagaaa aatttgtagt ttcaaaactt
    41881 aaatcagaaa ataaatattt agtagaagtt caaaatacag gagttaaaac ttcttatgta
    41941 gaactatatt ctaaaaataa agttgcaact atagacaata ttgatgaagg tataggaagt
    42001 atatctctag ctattcttct acaacaaggt aatatagttg gtaattttgg tagattagat
    42061 actgcaactt cattgttgcc atctattaag tagaaataac tttaaggaga gaaaaaatgg
    42121 attcttatat aagtataata ataccagctt ataatgaaga aagtagaata aaatatacat
    42181 tagaaagcat attggacatt aatcaaataa atgaaataat agttgtcgat gatggttcga
    42241 ttgacaatac tgctaaagct gtatctgaat tagaaaatga aaagattaaa ttttttaagt
    42301 tagataaaaa tagaggtaaa ggatatgctt taaattatgg tatcaagtta gcaatgaaaa
    42361 atgcagatgt tataggtttt cttgatgggg atttaggaag ctctgctaaa gaagttgaaa
    42421 aattaatagt acctatatta aatggtgagg cggatgttac aatagccaag tttcctcctg
    42481 caaaaagaaa aggaggtttg ggatttgtaa aaggtttagc taaaaattct gtgtttgaga
    42541 tgactggcgt tgagttagat gcaactttat caggtcaaag aatatttaaa agagaagttt
    42601 tagaaaagtt tgatgaaata ccttttggat atggagtaga agttggaatg accatcgata
    42661 tcttaaagta tggatttaaa attaaagaag tattagtaaa tatgacacat aatgaaacag
    42721 gaagaaattt aaaaggtttt atccatagag ggaaacagta ttatcatata aaaaaggttt
    42781 taggacaaaa aaagaaagaa tggaggtaat atcttagtga aagattatat actttatacc
    42841 attttattgt taactggatt atttggaacc tatgctgtaa ttccactatt taaaaattta
    42901 ttgataaatg gaaatgtact tagaccaaac tacaaaaaag atatgatacc agtaagtatg
    42961 ggaattgtat ttttacctat gattgtaatt aatggaataa tacttgcttt ctttactaca
    43021 gaatttaagg atttagcgta tatatttatg tttatgtttg gtatgatatc catgtttttt
    43081 gcagggatat tggatgatgt cattggaaat agagatgtaa gtggtttaaa agggcatttt
    43141 aaaagcttat ttaaaggaag tcttacaaca ggaggtttta aagctttatt tggtggattt
    43201 gtagggctta tagtttctgt tgctatatca aaagacataa ttgatataat agtaaataca
    43261 ctaataatag ctttatcaac taatttaatg aatcttttgg atttaagacc agggagagca
    43321 ataaaagcat atttattcat aatggtaatt atatttttaa cattgacagg atttgttcaa
    43381 gttcttccat tacttatagt accaaatgta cttgcatact ttaactatga tttaaaagcg
    43441 agggctatga tgggagatac tggttcaaac gttctcggaa tatctattgg aatgctcatt
    43501 tcttttgggt atccatttaa cattagatta ggatggttaa tatttgtagt tattatgcat
    43561 atattcactg agaaatactc gttaactaag ataatagaaa aaaacaaact attaaatttt
    43621 atagataaat tgggaaggta gtattatgat aagcaaaaga gtgggtattg ttgaatcaat
    43681 agtaagtcaa actgaaactc tagatgatat aagagtaaat ataaatggag aaatacaaag
    43741 ggcatataat tatccaaaca tatctggaac tataaatata ggagatgaag tcgttttaaa
    43801 tacaacagca gtagaactga gcttaggtac aggtggatac cattttgtaa taactaattt
    43861 aaataatata gaatctactt taactgaagg cggtcatata atgaaactta gatatacacc
    43921 tcttcaaata aaagtagatt ctgttgagga acaagaaagt atttatcatg ataaatttgc
    43981 gaattttaaa gggttagaag gtctttctgt tgtagtaggg actcttcata gtatgttaac
    44041 tccatttgta gcttcattta aaagaaataa tccaaataaa aaattagtat atataatgac
    44101 tgatggagca tctcttccaa tttatttaag taaaaatgtg gatactttaa aagaaaaaaa
    44161 gctaatagat agtacaataa ctataggaaa tgcgtttggt ggagattatg aatgtataaa
    44221 tatatatact gcactaatta cagcaaaaga aatactaaaa gcagatgtag tatttgtaag
    44281 tatgggacct ggaattgctg ggacaggaac aaaatatgga tttacaggga ttgaacaagg
    44341 ctctattctt gatgctgtaa aaaaacttga aggaagagca attgcaattc caaggattag
    44401 ttttgctgat aaacgagaaa gacatcaagg tatttcacat catagtatga ccgtatttaa
    44461 agaaattgta aatgtaaatg tagacatacc aataactata tatgatgatg aaaaattgaa
    44521 ctttataaaa gagcaaatca atttaaatgg tttaaacaaa aagcataata taatttatat
    44581 agataataat aaaacgaaag aggatttaga ctattttaat ctaaaagtaa agagtatggg
    44641 aagaaattat gaacaagatg aggcattttt caaagctgca agcacagcag catattactt
    44701 aatggaggtt taagatggta ttagaagaaa aaactattag tagtgatagg gtttatacag
    44761 gtaaagtaat tactttaaag gttgatactg ttgaaattcc agggcaagga tatcaaaaaa
    44821 gggagttagt agaggttggt ggagcagtag gaatagttgc aattacagat gataataaag
    44881 ttgtactagt taagcaattt agaaaaccta tagaaaagcc aatctttgaa attccagctg
    44941 gtaaactaga aaaaaatgaa agtccaaaag aatgtgctga aagagaatta aaagaagaaa
    45001 ctgggtatag tgcaaaaaat gttaagttaa tacataagtt tttcacttca gcaggttttt
    45061 ctaatgagat aatgtttgta tatttagcaa caggtcttac tccaggagag aataatttag
    45121 atgcagatga gtttttagat gtacatgaaa ttgagcttga agaagcatat aatatggtac
    45181 taaaaaatga tgttgaagat gcaaaaactt ctattggatt attattagta aaagatatgt
    45241 ttaaaaatta atatttataa aatgaataac cctttgtcct aaagcatatt attttataaa
    45301 ggacaagggg gaattaaatt gagaagaaca tatagaaaaa atgattttag agaattaaat
    45361 agacaaataa ttattatagg attgttgttt atgatgtcta ttgttgttgg gtcttacata
    45421 aataaaatat tgccaagttc tagtaacaat atattaaaca atataaatcc tgctgtagag
    45481 tattataatt taaatataag cataaaagat gcagtgatac aaaatttaaa atcagatgca
    45541 atctttatgg gctcaatagc tctattaagt ctgtttgtag taacaattcc agcagtgttg
    45601 gtagcttttg tattaaaagg gatgtcaatt ggttatacaa taaatagttg tatattggca
    45661 ttaaaattta aaagtataaa aatgatttta ataatattat ttaaaaattt gattattatt
    45721 ccatgtgcaa tcatattaac attaattagc ttaagttatt ttaaagaaat ggtttatgaa
    45781 tttaaaaaga aaaatagaaa aaatatgcaa tttttaatta agaggtatat actaaatatt
    45841 ataattataa tagcactatc attggggttg caattaatat taaatactgt aagtattggt
    45901 attattaagt tcctagctaa ataaaggagt ttataatgga tattatagag ggatatatag
    45961 attacataaa agataaaaaa aaattatcag agaatacagt ggcatcatac tttatggata
    46021 taaaaaaata tatggaatat ataaatcaaa aaagcattaa actaatagat atagtagaaa
    46081 atgatattat aagttactta ataaagttgg aaaaagataa tgtatcaata gctacaatag
    46141 cgaggatgat atcctctata aaatcttttc atgattattt atttttaaat catatatgta
    46201 caaataatcc tgcaaaggat ataaaaaaac ctaaaataaa aaaagaaaat ataaatatac
    46261 ttacagaaga agaaattgaa agactattaa attttccaaa gttaacaaca cctaaattga
    46321 ttagggacaa ggctattttt gaagtattat atggtactgg tataaaagta tctgaattag
    46381 tagagatgaa tatagaagat attgacctag acattgatta tatatattgt aattcatgtt
    46441 gtaaaagtca aagagtgata ccactttgtg atattacaaa actttattta gaaaagtatc
    46501 taaaagaagc aagacctaaa atggctgtag aaggtgaaaa atcattattc gtaagttcgt
    46561 taggtcaaag gtttacacga caaggtcttt ggaaagtcat aaaaaaatat tctaatctag
    46621 ccaatatcga taaaaatata aatcctacaa tgcttagaca ttcatttgca attcatctgt
    46681 taaatgaagg tgctaacatt gctgttgtaa gtaaaatttt aggaaatgtt aatttatcta
    46741 gtttacaagt atatttaaat catatagata aaaacgtgag aagagaaata aaggaaaaac
    46801 atcctagaaa tgatgttgat atagaattac aaaaagcaga ggctaaatag actatatagc
    46861 aaattttata atttagaagg agcatatttg tatgagcaga gtaatttgga ttgtaattga
    46921 tagtgttggg ataggagcat tgcctgatgc tgaaaatttt ggagatagta aggatgtaag
    46981 tactcttgga aatatattta gagaataccc agatataaat attcctaata tgagaaaatt
    47041 gggtatagga aatatagatg gtgtagattt ttttgaaagt ataaaaaccc caataggttg
    47101 ttttggaaag tgtaaagaaa tgtctcaggg aaaagatact actacaggtc attgggaaat
    47161 gactggtata atagttgaca aaccatttaa gacatttgaa catggatttt ccaaggagat
    47221 aatagacgag tttgagaaaa aaactggaag aaaagtagtg ggaaataaac cagcttcagg
    47281 aactgtaata atagatgagt atggagagca tcaaataaaa actggtgatg taatagtata
    47341 tacatcagct gatagtgtat ttcagatagc tgctaatgaa gaagtaattc ctctagaaga
    47401 actctataat atgtgtaaaa tcgctaggga aataatgatg ggggacaatg cagtagctag
    47461 agtaattgct agaccattca taggtaagaa aaaaggtgag tttgtaagaa cttcaaatag
    47521 aagagattat tcattagacc catttgaacc aacagttctt gacaatataa aagaatcagg
    47581 tcttgacgtt ttagcagttg gaaaaataga agatattttt aatggaaaag gaattacaga
    47641 tgctatccac actaaaagta atatggatgg agtagatgaa actttaaatt atatgaaaca
    47701 agataataaa ggtctgatat attcaaatct tgttgatttt gattctaaat atggtcatag
    47761 aagagaccca gaaggatata agaaagctct tgaagagttt gatagtagac ttcctgaaat
    47821 aatggctaat atgagagaag atgatatttt aataatcaat gcagaccatg gaaatgaccc
    47881 aacatataaa ggtacagacc atacaagaga atatatacca gttatgattt atggcaataa
    47941 gattaaaaaa ggttttaatt taggagtaaa agatactttt gctgatattg gagcaactgt
    48001 tgcagatata ctaaatgtaa agttgcctaa acatgggtca agctttaaaa aagatttatt
    48061 ttaaattaga aaataacaaa aacttagttt aataggatgg agagattgga atgtttgaaa
    48121 agatagcaca aagtagtaaa tttataaatg ctaaaattaa tataaaacct aaaattggtt
    48181 taatattagg ttctggacta ggcgatttag caaatgatat agaagactct gtcacaatta
    48241 aatatagtga aattccaaac ttccctatat caacagtagc aggacatgct ggacaacttg
    48301 tcattggaaa acttgaagga aaagaagtta ttgctatgca aggtagattt cattattatg
    48361 aaggatattc tcaaaaagaa gctacttttc cagtaagggt tatgaaagaa ttaggagttg
    48421 aggttcttat agtaaccaac gctgctggag gtgtaaataa agaatttaaa gcaggagatt
    48481 tgatgcttat aagagaccat ataaacttta gtggaagtaa tccattagta ggaaaaaatg
    48541 atgacagact tggtgataga tttccagata tgtcggatgc atattcttct agatatgtag
    48601 atgtagttaa aaactgtgct aaagaatgta atatagatgt caaagaaggc gtttatatgt
    48661 tttttagtgg tccaaactat gagacaccag cagaagtgag aatggcacaa attttaggtg
    48721 ctgatgctgt aggtatgtct actgttccag aagtcatagt agcttcacac tctaatatag
    48781 gagttattgg tatctcctgt ataacaaata tggctgctgg catcttaaat cagtcactaa
    48841 gtcatgagga agtaatagaa actactcaaa aagttaaatc agaatttatg aatttagtta
    48901 aaacaacagt taaaaattta taagttgaag attattataa attttttgag caaatttata
    48961 ataaaatagt taatgtttaa tttaaaagga ttaataaaga gctgtcttga tatagaaagt
    49021 tatttctaat aagggacagt ttttttataa tactacaaca tttgaaagtg ttttaaagtt
    49081 taatatttat ttaaattatt ataggttaga atggagattt caattatgag aatgtatgat
    49141 attataagaa aaaagagaga taacctagag cttagtaaaa aagagataaa ctactttata
    49201 gaaaattatt caaagggaga tatacctgac tatcaagctt ctgcactatt aatgtctatt
    49261 tatttgaata agatgaataa acaggaaact gtacatctta cagaagcaat gatgaactct
    49321 ggagacatga taaacttatc tgagatagat ggaataaaag tagataagca tagtacaggt
    49381 ggtgttggag ataagactac tatagctctt atacctttgg ttgcttcatg tggagcacca
    49441 gttgcaaaga tgtcaggtag aggtcttggt catactggtg gtacgattga taaattggag
    49501 tctataccag gtttctcgac agaaatggag ataagtaaat ttattaattc tgtaaataag
    49561 tctaaaatag cggtttgtgg tcaaagtgca aaggtagcaa ttgcagataa gaaaatatat
    49621 gctcttagag atgttacagc aactgttgat aacatatcat tgatagcatc aagtgtaatg
    49681 tctaaaaaat tagcttcagg agctgatgca attgtgttag atgtaaaaac tggtgatgga
    49741 gcatttatga agacgttaga agagtctttt gatttagcaa agtctatggt tgatataggc
    49801 actggtatga atagagatac aatagggatt gtaacagata tggatgaacc tttaggtttt
    49861 gcagtaggaa actctttgga agttatagaa gcaattgaga ctttaaaagg aaatggtcct
    49921 aaagaccttg ttgagctatg tgaagtacta ggagcatata tgctggtttt atcaaaggta
    49981 gcatatgatt ttgatgatgg tgttgaaaag ataagagaat cgataaaatc tggtgacgcc
    50041 atacataaac tcaaagagtt tatagagaac caaggtggta ataaagatgt agtagatgat
    50101 tattctttat tcaaaaaatc aaagtataaa tatccagtta aatcaactaa atcaggttat
    50161 ataaataaaa ttaaagctga agatgttggt gtatcagcta tgattcttgg ggcaggtaga
    50221 gaaactaaag atgatgtttt agatttatca gtggggataa ttttagaaaa gaaagtagga
    50281 gattatataa atgaaggtga agttttagcg tacatgtatt ataatgatga acaaaaactt
    50341 tcattggcaa aggacagatt tattgattcc tattctattg tagattcgaa ggtagaaaaa
    50401 aataaactaa tatacggtat tgtaactaaa gaagggatta aaaagtttta gaaaatttta
    50461 gaaaagtgat tataaaaggc ctaacatgtc aaaaataatg ttaggttttt tattttttga
    50521 taagttgtaa attataccaa aaatatatat tttaaaacat tttttacaat ataaataagt
    50581 ttattctaca agatgattga aaattaaagt atctagcttt ataatagaaa atggataaat
    50641 atacataagg agtagattat attatgaact ttaaagaaaa tagattgaaa atagcagcat
    50701 taataattgt tattttgatt atcttagcag gtatatttgt gtctatgcaa ataggtcctt
    50761 ataataaaaa taacaaaaaa gatgtaatta ttgacattcc aaatggagca tctattggaa
    50821 aaatatctga tatattatat gaaaataaat taataaaaaa tgaactatta tttaaacttt
    50881 tggtaaaggt tagcaataaa gctccatcta taaaatcagg aacatactta cttaatcaat
    50941 cgtactcaaa taatgatata ataagtcttt tagtttcagg taaaatatat caggatggta
    51001 taaaagtgac tattccagag ggtgctacat ctaaagaaat tatagcaatg ttagtaagta
    51061 aaaatttagg agataaagct acttttgaaa atttaataaa aaaacctcaa gaattttatg
    51121 ataaatttcc atacttaaag gaagatggaa taacttcttt agaagggttc ctgtatccag
    51181 aaacttatta ttttaattca aagaaacaat cagaagaaga tattttaagc gaaatgttaa
    51241 aggtatttga cagtaaatac acggacaagt ttaaaaagaa acaaaaaaaa ttaaatatga
    51301 ctcttcaaga agtaatggaa atggcatcaa taattgaaaa agaagctgtt cttgacaaag
    51361 atagaccaat aatagcaagt gtgttttata atagacttaa ggtaggtatg cctcttcaat
    51421 cagatgcaac aatacaatat atatttgaag agagaaagaa aattgtaacg tatgatgatt
    51481 taaaaattga ttcaccatat aatagttata aaaataaggg attacctcct acaccaatat
    51541 caaatcccgg tataaaatct attgaagccg cgttatatcc agataaaaca gactatttat
    51601 attttgtagc taagattgat ggtggaaata attatagtac aaactatcaa gaccatttaa
    51661 aatatgttaa agaatataaa gaagcaaggg ataaacaatc aaaagataca aaagcaacaa
    51721 ataaagaaaa tacaaaaaaa taaaccatga ttataaaaag cctaacaggg taagaataat
    51781 gttgggcttt tttattgaaa attgttattc ttagatttat aataaagaaa gtgtaaatat
    51841 atacaacaat atgaatttaa aaaataataa attaatataa aacttgaaca tttattattt
    51901 tagggagtgt ttttatgagt aatatagtta atgatttggt cgaagattat ataagagtga
    51961 cattaaaaga aaaagaagga tttttaaaag atttagaaat ttatgcagag gaaaatagtg
    52021 ttcctataat acataaagaa gtttcagatt tattaaaagt cttattaaag attcaaaaac
    52081 caaagagagt tttagaagta ggatgtgcaa ttggttattc ttctattttt tttgcaacta
    52141 ttataggaaa agatgcagac ataataactg ttgagagaaa tgaaaaaatg atagaaaaag
    52201 caaaagaaaa cataaaatta gctggatttg aaaataacat aactatacta gaaggagatg
    52261 cagaagaaaa acttagtcaa gtccaaggtg aatttgacct tatatttata gatgcagcca
    52321 aaggtcaata taagctattt tttgatttag ttatagataa attaaaagat ggaggacttt
    52381 tagtatctga taatatttta tataagggta tggttgctca tgatgatttt gttgtaagaa
    52441 gaaaaaagac tatagttaaa agaatgagaa attatttaga ttatatatgt aattgtgatt
    52501 atttaagcac atcattgata ccaataggtg atggtgtagc actaagttat aaagaaagta
    52561 aaagaggtga tgtagatgga attaaataaa gtagaacttt tggctccagc aggtgatttg
    52621 gagagattga aaatagctat aacatatgga gcagatgctg tttatatagg tggagaaatt
    52681 tttggaatga ggtctgcagc gaagaatttt agtaaagaag atatggcaga aggagtagct
    52741 tttgcacatg aaagaggaaa gaaagtattt gtaacagtaa atataatacc tcataatgaa
    52801 gattttctac aattagaaga ctatttgttg gaattagaag agataggaat agatgcagtt
    52861 ataatagctg acccaggagt acttagtgtt attaaaaaag taattcctaa tatggaaata
    52921 catttaagta cacaagcaaa tacgaccaat tatctaagtg cgaacttctg gtacgagcat
    52981 ggaataaaaa gggttgtagt ggcaagagaa ttatcttttg atgaaatatc tgagataaga
    53041 gcaaaaacac ctttagacat ggatatagaa gcgtttatgc atggtgctat gtgtatttct
    53101 tattctggta gatgcttaat aagcaactat atgactggaa gagatgcaaa caaaggttct
    53161 tgcgctcaat cttgtagatg gcaataccac ttagttgaag aaaaaagacc tggtgagtat
    53221 ttcccaatat atgaagatga aagaggtaca ttcttcttta actcaaaaga tttatgtatg
    53281 atagagtata taccagagtt aatcaaatct ggtataacaa gtttaaaaat agaaggtaga
    53341 atgaagactg catactatgt agctactgtt gtaagagcat acagaatggc aatagatgaa
    53401 ttttacaaag acccagaaaa ctggaagttc aatccaatgt ggatggaaga actaaaaaaa
    53461 ggtagtcata gacattttac atcaggtttt tacttgaata aaccaacaac agaagaccaa
    53521 aattatcaat cagcatcata tgttagaaac tatgatttta tagggatagt tagagaaaca
    53581 gaagatgaag atggtcttat tgttgttgag caaagaaata aaatgtgtgt tggtgatgaa
    53641 atagaggtca tgggaccata taaagaaact atgtttacta aaattgaagc aatgtacaat
    53701 gaagaaggag aagctataga atcggctcct catcctagac aaatagtgaa gttaaaacta
    53761 tcagtaaaag ttggtaaaga ttatatgctt agaaaagtta tagaagaaaa ggttgaagaa
    53821 taataaaaaa ttgataaaaa tagtattagc cccttagaaa ttgtcaataa tgaaattatc
    53881 taaggggtga tttcatgtca aaaaagaaga ctccattttt gaaaaaagtg ggaaagagaa
    53941 gctggtgtgt atttactata attttaataa tttatagtgc tttaatttat aggctagttg
    54001 atatacaagt attaaaaggt gataaataca aacaaagtgt tgaatcacaa agtgttgaga
    54061 aagtcgagct aaacagtgga agaggaataa tatatgatag aaacaacaag aagcttacag
    54121 atacaagtaa gtatcaggta ttagttgttg aaaaagaaaa attaaataat aactataaaa
    54181 ttttggagct tattaagaaa gctactaaaa tgaatgattt agatatatat aaagctgtac
    54241 aagagcaatt gacacgccct ataatacaga ttcaggctaa aaatatcgat aaaaatatga
    54301 aaaaagaact tgagaaaaat ggaataatga tagaagaaaa aactatgaga tattcaaaag
    54361 atggtttatt atcacacaca ataggatata taaaagaaga tgataaatca ggtcagtcag
    54421 gaatcgaaaa aagtatggac agtgtactta gaaattcaaa tgaaaagtat ataagtgctt
    54481 ttaaagctgg agatgcagga aatgaaaaat ctctaaacat actaaaggga agtgtaaaaa
    54541 ctattgataa taaagataaa gatagacatc taaaaactac tattgattat aatattcaaa
    54601 ggaaattaga acaaatatta aataaagaag aaaatcctac agcagcaata atctcggagg
    54661 tatctacagg tgaaattctt gcaatgtgtt ctagacctaa ttttgaccaa aatgatatat
    54721 caaaaagttt aaaaggaaaa aatggtgaat ttgaaaatag agttataaag gcgacatatc
    54781 caccagggtc tgtatttaag atggtagtct tattttctgc acttgaaaat ggtgttatag
    54841 atgaaaacta tacgtacaac tgtacaggca agactaaagt tgggaatact aatgaaatac
    54901 tacgatgtaa taaaagagat ggtcatggtt tccaaaattt aagacaagct ttttctaatt
    54961 catgtaatcc tgcattttta gatatagcta tgaagcttgg aaaagaaaag atacttaaat
    55021 ctgctgaaaa gttgcattta tttgaaaagg ttgatattgg tcttgatgaa gaaaaaatta
    55081 gagaagctcc aaaaaacata tcaataagaa atttagctat aggtcaagaa aatatagaat
    55141 ttacaccact tcaaataaat caaatgactc aaataatggc gaacaatgga acattcaaac
    55201 cattatactt atataagagc cttgtggata atgatatgaa tacaataaaa acttataaat
    55261 cctcaaaaaa ggaagaactt atttctccat atgtatgtac acaagttaaa gaatatatga
    55321 aatctgtgtc taggactggt acagctaagg acctaaaaga tattgagggt ggatgtgggg
    55381 ttaaaactgg tacagctcaa agtagtttga ataaaaaagc aatagaccat ggatggataa
    55441 ctggatttta tcctgaagaa agacctaagt atgtaataac tgtattagta gaaggaactc
    55501 aaaaaggaaa taaatctgca acacctatat ttaaggaaat atgtgaaagt atacaataaa
    55561 attatatact ataaaattta aggatatatc gtaatcttga ttttagatag aaagttttgt
    55621 ctagtgatgt acgatatatc ctttaaaaat gtagtattaa ctttcttgaa caagctcttt
    55681 ttctagtttt ttaagagctt ttttctcgat tctagataca tatgacctcg atatatcgag
    55741 tttttgtgca atttctcttt gtgtcttata gccataagga gttaacccat atcttaactg
    55801 gacaatttct ctttctctag gagtaagaat tttgtttagt tgttcgtaaa gctttccaac
    55861 ttgaaccttt agctcaactt catcaagaac atagttagct tctgtgccaa gtatatctaa
    55921 aagacttatt tcattacaca ctactcttta tatgttattg gtattactag tcttcatgta
    55981 atttcaaatg aaccattaat tcaaaagaat ccaatttttg ttctttagac ttataataaa
    56041 ctgctttatc aattacagat tttaggagtt tattttttcc aagggaatct gaatcatggt
    56101 aaagtgataa cacagtttta atatcttcta ttattttagc attgtctttt ttaacagtac
    56161 tcaatctatt ttttactgtc ttaattgaat ctttaatttc ttcagttctt gaacttatat
    56221 tgttggacct ttcaataaat gtatcttcat catatattcc acgttctaat aaatcatata
    56281 acttattttt ttgcttactc aattctttta attcagtttc taaacccttt aagactcgct
    56341 tttgaaattc tatattactg tctttattat ttttatctaa gtctatgtca gatgttttta
    56401 attgatattt ttttacagtg tcttccaaag attttaaaat agcagcttca ataaattcaa
    56461 atcgagaact tttattgcaa ccaggatggt aacaaattat atagttgtgg tctgcatatg
    56521 gtctatatac taatggccta ccacaatttt tacaaatcac tattcctgca agtggatttt
    56581 ttatttgatt accatagctg acatgaccat tttttttgag tatattttga gcctttttcc
    56641 atgttatttc acttattaaa ggttcatgct ttccttttgc ttcaatccat tcatctttag
    56701 gtcttaattt aactgttttt attttatttg gatttttaga ttttttatag tccttttttt
    56761 gccactgaat gtagccacag tagactttat tttttattat atttgtaatt gcagaattgt
    56821 accaattagc acctgtagca gttttaatgc ctaggttatt taggtatttt gatattttac
    56881 tacaacccat atcttcattg atatataagt caaagatagt cctaactata tcagcatctt
    56941 tatttggtac aagtattctt tcttttctac cagttgttac agcatcatat ccaaatggag
    57001 cagaagttcc tatgaaattc ccttcttcaa ctgattttat tctacctctt tgcatccttc
    57061 ttgatataag ttttagttct tttcttgcca taaatgcttc aaattctgaa tactcttcat
    57121 caaattcatc tgttaggtcg tatgtttttc taggtgtgat gattttggtc ttactttctt
    57181 taaatgtttc tagtatgata ccttggtctt tcatgtctcc acgaccaagt ctgtctaagt
    57241 ccattactaa gactgcgtcg tatttatttt cttcgacttc ttttagaagt tcaagcattt
    57301 tgggtctatg tattatactt tcaccagaaa ctaattcttc ttttatctca attacatcta
    57361 agctttgttc ttttgctagt tttagtaggg ttgatttatg cctacttaaa gtttcaaatt
    57421 cgccttgttt ttctgcttct tcatcagcac gggattttct caagtatatg gcaacactca
    57481 tataagtaat cacactcctt aggtactatt atatattata ttaaggatat aatgggataa
    57541 tttatgctaa ttaaaacttg atataattgt aaaaatagta tgaaaattta gcatgaatcg
    57601 acagcattca atgagaaaat atagtataat gcaattgaga ataattttta gggggtaatt
    57661 atatgtgtaa ttttaaaaaa atactaggct tgtttatgat aattatgtta tcagtttcta
    57721 tggtagcatg ttctagtggg ggagattcaa aagatgaaag caaaggtaag gacaagcaat
    57781 ttattgagga tttaggaaaa ggcttaaaaa aaagatggga tttggcatct aaagaagaag
    57841 ctggaacact aaacttagag cagaatgaag cttatgaaaa atttgtagaa gtagaaatgg
    57901 atgctgtatc aaaatataaa gatgctgagt ttgatagccc agaacttggc aagttggcaa
    57961 aagattatat aaaagctctt gaagattcaa aggaagctat aaaatattat tcaaacgacc
    58021 aattaaaatt ttcagaactt tgggaaaagc cttataatga gagaagcacg atattgttga
    58081 ctttagttga taagtttggt ttgaaagtag atgaaaaaga gtttaaagta ttaaaagaca
    58141 atgcacaaat cgtaaatgaa gaaaatgatt taaaagaaaa agttaatgct atggcaaaag
    58201 gtataaaatt tgaaaaagta aaagatgaat atgattggaa gacttatcaa gctactgtag
    58261 aaaatacaag tgatttagat cttcaagatt tttacttaga tataaatcta atagacaaag
    58321 atggtgtaat aatcgagaca caaacatcaa catcagtaaa tggaacttgg aagaaaggtc
    58381 aaaaagttag acttgagttt agtacagata aggattttga aaaaatagag tggacacctc
    58441 attattctgc aaataattat agtataactg aatagataat ttgtatttaa aaatatttag
    58501 aaggggaaga tattatgaaa attaaaaaat tattaacaat agggttatct ttatctatgt
    58561 ttattgctag ttgccatata tctgcaaatg ctcttgataa aattgaatca attaaaggtg
    58621 cagataaata cgaaactact ggtataattg cagataaaca aaactatact acagctatat
    58681 taattaatgc agatagtaca atggctgatg gattaagtgc aagtggactt gcaggagcta
    58741 caaacgctcc aattcttttg actaagaaaa ataacatacc aaatgctaca cttaaacgat
    58801 tagaaaaggc aaaaaaagta tatataattg gaggagaaaa ctctattgat aaatatactg
    58861 aaactgttct aaaaggtaaa ggaatagaga ttaaaagact tcaaggtagt gatagaatta
    58921 agacaagcta taatgttgca aaagaaataa attcaattaa caaagtaaat aaagtgatat
    58981 tgactaatgc ttttaaagga gagcctgatg caatgagtgc tgcacctgta gcagttagag
    59041 agaaagcagc tatagtatta actgatggaa aaagtgttcc atttaataca actggtgtag
    59101 aaagttatgt aataggtggt acttcatcaa tgaatgacaa actagttaat gatactaatt
    59161 caactagatt aggtggcaca gatagatatg atactaacaa aaagataata aataaatttt
    59221 atggtggagt aaaagaattt tatatagcaa gtggtactga tttagtgtat gctcttgttg
    59281 gttctactgt tgctaaaaat aatgctattg tgttagttaa taatgatagt aataaaagtg
    59341 tattaaaaag cacaactaaa ttaactgcta taggaaattt gagtgatagt atattacaac
    59401 agtgtttaaa tgtaacaaaa aatataggag attctaatac tggaagacaa tatacagtag
    59461 aagatgctgc taatgcagta aaaaaactgc taggtgtgaa gaaattttat tataatgaaa
    59521 attatccaga agatgaagat gtaatattct tactagatga gaattttgaa ttttcaggaa
    59581 aacaattcta tgcatttggt tatgttacag aaaattctga aggggatgtt agatactgtg
    59641 tagagaaaaa tgatatgagc aaagtttata catataatgt tagtggagtt atgcaagtat
    59701 gtaacccaga tgattataaa aagaaggaaa tgatatcaga agaaaaagca aaacaattgg
    59761 cattagaaga gtgtgccaga aaacataaag ttggtgttga tttattaaaa gttaatattg
    59821 cttatattga tgattttgat gatataaaag tatatgctgt aagaatagat tcaaaaccac
    59881 atccaaatca aacctatgga tggtatttta tagatgttta tagtggatat gcttataagg
    59941 atgtttggaa taacatttaa atagtgtttt taattatata atttaccaat atatgttata
    60001 ataattttag caagaagatg taatctacaa tctatagagt ggagttcata caaacaaagg
    60061 attatcctcc ccattttaag aagggaggtg attatgtatg gataattttt tacttagtat
    60121 attagccagt attctggcta gctatatagt ttacttaata agtaagttat ttagaaaacg
    60181 taaaaaacca ctcaaagctg gcactaagag tggttgggaa cttgatttta aaataaagtt
    60241 ccataaattc aaataacatc gtttatgatg aactccactc tactgctaaa tagattgtag
    60301 ttcttcttgc ttttattata ccacaaattg gtgcagatat tcaaaaataa tatatttata
    60361 atataataaa attatagaag ttttgcagtg agcgaaattt gtgataaaat atggcttaac
    60421 aattggaata taatgcattg aagatgtgtg ataagtatta tcaattgcac tactcatggt
    60481 tcactgcaaa tttaagagag ttgtatagat gtaagtattg gaaatactca atttgttttg
    60541 gggttttata ttaactaagt ggtatgtaaa gctcaaaatt aaatagttgg ctatggttaa
    60601 gggattgccg ttttatatta actaagtggt atgtaaagat aatagcagat atgatgttta
    60661 ataacggaag tataaggttt tatattaact aagtggtatg taaagctgaa tgaacctaag
    60721 gtagttgaac agattgaaaa gacgttttat attaactaag tggtatgtaa agtatgtcag
    60781 gacttcttaa accatattca gcatacactc gttttatatt aactaagtgg tatgtaaaga
    60841 aatttaatat tgctggaaaa ggagaaatgg atattggttt tatattaact aagtggtatg
    60901 taaagaatgc tgaacttaaa gtaatgatgc tattttggga cagttttata ttaattaagt
    60961 ggtatgtaaa gaaatttgca aggctaaatt gccccttaat taatggtggt tttatattaa
    61021 ctaagtggta tgtaaagagt ttttctatat attcagatat ttcactttta tcttgtttta
    61081 tattaactaa gtggtatgta aaggaaatat gtatagaagc attgaaacaa gataaatatt
    61141 gttttatatt aactaagtgg tatgtaaagt ttatattcct cacacatata atacaattaa
    61201 ttcagtttta attgtcatta tgctcaatat ttagtttttc tgtatcttat aaaccaagaa
    61261 tataattgat agagacacca aaaattttag caaatattat taactcatca tctcttattg
    61321 gtctttcatc agactctatt atattcataa cacttgtatt tatatttgtt ttttcaaaca
    61381 attatttttg tgacctattc atattttccc taatatattt aatcacttga cttatgttca
    61441 tacatgatca cctcgaaaaa tttctattgt agagttgtaa aaaatttagc tttaaaatat
    61501 agaatatcaa gtgattttaa gtaagaattg taacaattaa ataagtataa gacaagttta
    61561 tgagttcata ttttataaca aggggtgatg ttatgaaaat actacaacaa tttaaaccat
    61621 acaaatatga taaagaaaaa aatatagaat atgatgaaaa aattatagct aatcaaaaca
    61681 cagaagttta tatagtatat ccacgtatat ctgatgaaga aaataggaga agatgggaag
    61741 agttcaatga agtagctaaa gaagtagcca ttaatatagc tatgaagaaa gttgagacag
    61801 tagaaagtta agagaataga gaagttgcta atacttagca ctttctcata gaagaaaatt
    61861 ggacaactat ttttaaataa ctaggaataa aaaagttaaa tcatatttga aaaaaggtga
    61921 taaaattgtt gagtattgtt attagtaata agaatgtatt aactattaaa agaaactata
    61981 agtttttagt aaatatagta tttaaggata ttataaactc tgcctgtttt tcggggtctg
    62041 gattgttcct tgcattgttt atcgttgtct gcatttctac tatggcttct gcaacagaaa
    62101 tgccatgtgc acgggcaaca atctttaaca ggtattttgt atctcgtttc ttaaatccaa
    62161 tcatatatat gactcatttc ttaatttgac catttgcaac cataactcat ggtgtgattt
    62221 attttatgac acccttataa gagaaactat aataaatgag aatgaataaa accgtatcct
    62281 gttaatcaca tgtttaatgt gaaatacggt tacggttttt cttcgttgaa tttatagcca
    62341 acaccccaaa cagtcaatat gtactgtaga ttatctgagg acggctctat tttctatctt
    62401 atttcttaac tttcgtataa atgatgtcag attgctaccc tctggcgcat tattgaagct
    62461 ccatatgtta tcatatagtt gttatttcgt gaataccatt cctttatggc aaaagagaaa
    62521 atacatcaaa tcaaattctt tagcagttat atatataatt tccccttttt cccacctact
    62581 ttatagcaaa caaatctaaa tattcttaag taacataatc tttatataat acatattcct
    62641 aataacaata gccagaaagc acttaatgat gaaaaaaccc tattaactat gaacaatttt
    62701 ttaataccta aaaattctaa gttgccgata aaaagaccaa ttgctatgat tatacctaaa
    62761 agcccaatcc aatttgctac ataatttata gacagtaaac tcattgaatt acagaaaatc
    62821 ataaaactta aaaatacaaa tgcaacatgc tctgtcatgg tttcacctat atatgtgttt
    62881 aatactttgt ataattgtcc agcttctttt tcagtaatct gtttatttat catctggtta
    62941 gacaacattg gaaaggtctt tgtatatctc aagattccta cgaatagaag aactccgtag
    63001 attattccat tgatatatgc aaagtttgac caaataaatt ctcccttact ttgttcaata
    63061 aaacgtaatg caatagatgc ctggacaacc ataaaaccac caattccaaa tagatagaat
    63121 agcaaagaaa tcatagtttt cttattctgc attctcttta gaattataat aggattttct
    63181 ctaataattt taggataacc aaaactaaac attaaaccta tcatacttcc agcaatacaa
    63241 aaagctgata atattgataa aacacctaca actatattca tattttcctc ttttctaaat
    63301 tatatttttt aaatatatca aagtaataaa actaacttat tgtcttaaaa tttctagaat
    63361 atctctcaat atgccgttga acttttctat ctcttcttga ctacattttg ataaaacttg
    63421 ataaatctga attttcatat tcatttcctg ctcattgtga ttatgataaa tttgttctcc
    63481 aagagtagtt aaatagatag gaattgtaca tccgttacct tgttctcgtc gcatttcaat
    63541 taaatttttt tcttgtaaat gtgcaataat gacggacatt cttccttttg ttacacctac
    63601 ttctttacat agttcttttt gcagaatacc tggcattttt ccaatcatta caagtgtatg
    63661 aatctctgca atatataatt tatcatcagt tccataggac tttgaatttt tattacgttc
    63721 agaagcccaa tttaaaatct gtacaaaagt attaaatatc tcatgttctt ccatttttgt
    63781 tcacctctaa atacagttta ccccgtaaac tgtaagaggt caagtcatat ttgatagaac
    63841 attctattat tataaaaaac atgtaaataa gggttactgc tatttagatg tagaagtaag
    63901 gttttatatt tatcttactt taacatcttc cagttgctat ctttgtgaat cctcaactca
    63961 aactgtgaaa tctgtgtcac ctttgtctga ttatcaataa acttcactga caagccgatt
    64021 ttcattgttc gtgagttttt ctgttttatt acttttttct cgttctcttt tttcttgaac
    64081 atgatttcaa ttcctttcta ttgtttgata cgtcctgcac ctattaggtg ctgttgcaag
    64141 taggcactcg taaggtctgc atagccaatc ggattgttca catggtacat atggttgttg
    64201 ccaatgtata ttccgatgtg gcttatatag ctaccgttgt tataagtaga gtggaaaaac
    64261 atgaggttgt cagcttttgc ctgtaaaagc gggatgagct ataaaagaga aagattattt
    64321 aaaagttgag aaaaatagtt tctttagttt tattcataac aattcattta agggttttat
    64381 ttcagcacta catgatgatg acgttttaga tagtaaaagc ttggacaaat tagaagaata
    64441 ttttaaaaat tttcaagaaa aatgtattga tgactaataa agctatcagt atctttttag
    64501 tttgagaaaa ttgagaatag tgttttgatt taatgctagt gttatgtaat ggtagaaaat
    64561 tatataaaga aaagtgctta tttccttgta tttgatagta aaaaatttag aaaataatac
    64621 cgattaaaat ttaaagaaat atatgaaata ctacaatagt ttaaatcatg caaatatgat
    64681 aaataaattg aaattataaa agctatataa ttttagaaga aatagttgac agataaattg
    64741 ccttactata ttattgtatt aaatcattaa tacaataata tagtaaggag gtaatgaatg
    64801 aaatctaaaa aatacaatat tacaaaagga ttatttatag tttacataat tattttgaca
    64861 tggataatac tattcaagtt acaatttgat gtttcatcca ttgaaaccat gaatcttaga
    64921 agcataaact tagtaccttt tgctgggtca cttataatta ataataaagt agatatatca
    64981 gagattatat taaatgtggc tatatttata ccatttggga tatacatatg tatgctaaaa
    65041 gaagagtgga gctttataaa aaaagttata cctattttta taactagttt ggcatttgaa
    65101 acacttcaat atatatttgc actaggtgca agtgatataa ccgatttgat aggaaataca
    65161 ctaggaggaa tcataggaat agctgttttt atgctattgt cgaaaatatt taagaataat
    65221 accataaaaa ttattaatat attagcattt attgtgacaa ttattgttgt attattttta
    65281 ggcttagtta tttttgcaaa cttatagaaa taagtatata ggtttaactt aaaatagagc
    65341 gtaaaataca gttacatata aacttattta cacataagaa gcacctatat agacatataa
    65401 gtgcttctta aattattaaa gaattattgt atcttgaaac tcttgtatat tcaattcttg
    65461 attttctctt gttttttcta ataaatctaa cgcacaattt atacaaactt taatttctgc
    65521 attggtattt ttttcataat aagttatata tttgtttcta tatttatcta tttcttttcc
    65581 acaacgacta cacattacaa ttacgctcat agcttagtac ctccatctct aattattctt
    65641 aatatattca atagtatcac ttttctgaaa ataatgattg ttaaaactgt atcaaatata
    65701 gatttacttt ttattataat gcattttaat aaaaaaataa aggttatgag taaaatattt
    65761 atagaaaaaa gtatattatt gaattgatta taaagtttta ttatttttat cattcttaaa
    65821 tacacattaa tatctataaa atgacaaaat aaaatatact atttaaatag atattaaaaa
    65881 attgatgcca agtatttgtt tgctatatga ataacaattt atttaggagc tttgatttga
    65941 cactgtataa tgataacgta attgttaaaa aagtttgctg atttggatgt gtttttagaa
    66001 aatagaaaaa tatatactta ctgactaatg ataattttat atgtatttta gtttgagtga
    66061 tttaagaaaa gtgttttgaa gggggagtat tttatagagt aactaaatat atataatagt
    66121 agaaaataac atataaaaag tagtgt
//
LOCUS       DBGJFK010000013        58262 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.013, whole genome shotgun sequence.
ACCESSION   DBGJFK010000013 DBGJFK010000000
VERSION     DBGJFK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58262
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.013"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(40..813)
                     /locus_tag="ACOIAP_001060"
     CDS             complement(40..813)
                     /locus_tag="ACOIAP_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HGZ2637968.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(813..1220)
                     /locus_tag="ACOIAP_001061"
     CDS             complement(813..1220)
                     /locus_tag="ACOIAP_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2637969.1"
                     /translation="MACETIKMEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVA
                     VSEACTNAIKHSKDDMFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLG
                     LFIIKTLMDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1224..1541)
                     /locus_tag="ACOIAP_001062"
     CDS             complement(1224..1541)
                     /locus_tag="ACOIAP_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HGZ2637970.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHGLIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     MEG"
     gene            complement(1553..1813)
                     /locus_tag="ACOIAP_001063"
     CDS             complement(1553..1813)
                     /locus_tag="ACOIAP_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HGZ2637971.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1813..2109)
                     /locus_tag="ACOIAP_001064"
     CDS             complement(1813..2109)
                     /locus_tag="ACOIAP_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGZ2637972.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2178..4604)
                     /gene="gyrA"
                     /locus_tag="ACOIAP_001065"
     CDS             complement(2178..4604)
                     /gene="gyrA"
                     /locus_tag="ACOIAP_001065"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGZ2637973.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFNLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4622..6523)
                     /gene="gyrB"
                     /locus_tag="ACOIAP_001066"
     CDS             complement(4622..6523)
                     /gene="gyrB"
                     /locus_tag="ACOIAP_001066"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGZ2637974.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESH
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPVTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPAKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6524..7639)
                     /gene="recF"
                     /locus_tag="ACOIAP_001067"
     CDS             complement(6524..7639)
                     /gene="recF"
                     /locus_tag="ACOIAP_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGZ2637975.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRVNKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRTFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKSIHVDEALLDVYDDTLARYGSYIYILRRDFIKKIASISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEISHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7656..7862)
                     /gene="yaaA"
                     /locus_tag="ACOIAP_001068"
     CDS             complement(7656..7862)
                     /gene="yaaA"
                     /locus_tag="ACOIAP_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGZ2637976.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(7999..9105)
                     /gene="dnaN"
                     /locus_tag="ACOIAP_001069"
     CDS             complement(7999..9105)
                     /gene="dnaN"
                     /locus_tag="ACOIAP_001069"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGZ2637977.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9347..10666)
                     /gene="dnaA"
                     /locus_tag="ACOIAP_001070"
     CDS             complement(9347..10666)
                     /gene="dnaA"
                     /locus_tag="ACOIAP_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGZ2637978.1"
                     /translation="MDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILLA
                     PSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYPN
                     LNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHHI
                     VSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERTQ
                     EEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIAI
                     LRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEAL
                     KDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTDL
                     SLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11325..11462
                     /gene="rpmH"
                     /locus_tag="ACOIAP_001071"
     CDS             11325..11462
                     /gene="rpmH"
                     /locus_tag="ACOIAP_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGZ2637979.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11540..11884
                     /gene="rnpA"
                     /locus_tag="ACOIAP_001072"
     CDS             11540..11884
                     /gene="rnpA"
                     /locus_tag="ACOIAP_001072"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGZ2637980.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEVYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11916..12167
                     /gene="yidD"
                     /locus_tag="ACOIAP_001073"
     CDS             11916..12167
                     /gene="yidD"
                     /locus_tag="ACOIAP_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGZ2637981.1"
                     /translation="MNKIIYILKEISRYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFIKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            12199..12906
                     /locus_tag="ACOIAP_001074"
     CDS             12199..12906
                     /locus_tag="ACOIAP_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HGZ2637982.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYILAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12875..13504
                     /gene="jag"
                     /locus_tag="ACOIAP_001075"
     CDS             12875..13504
                     /gene="jag"
                     /locus_tag="ACOIAP_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGZ2637983.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKIKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13616..14995
                     /gene="mnmE"
                     /locus_tag="ACOIAP_001076"
     CDS             13616..14995
                     /gene="mnmE"
                     /locus_tag="ACOIAP_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGZ2637984.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGERALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDKENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKDKTDELKKEIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVERSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15090..16985
                     /gene="mnmG"
                     /locus_tag="ACOIAP_001077"
     CDS             15090..16985
                     /gene="mnmG"
                     /locus_tag="ACOIAP_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGZ2637985.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKEQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQVRR
                     TRGGKGE"
     gene            16978..17697
                     /gene="rsmG"
                     /locus_tag="ACOIAP_001078"
     CDS             16978..17697
                     /gene="rsmG"
                     /locus_tag="ACOIAP_001078"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGZ2637986.1"
                     /translation="MNNMELLKNGIEGFNIDTNDSMLEKFKIYREILIDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDRLELTLLDS
                     LNKRINFLEEVSRVLELDNIKFIHGRAEDFGKNENYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEIDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17860..18645
                     /gene="noc"
                     /locus_tag="ACOIAP_001079"
     CDS             17860..18645
                     /gene="noc"
                     /locus_tag="ACOIAP_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0032466 - negative regulation of
                     cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HGZ2637987.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKIQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18780..19553
                     /locus_tag="ACOIAP_001080"
     CDS             18780..19553
                     /locus_tag="ACOIAP_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2637988.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19555..20418
                     /locus_tag="ACOIAP_001081"
     CDS             19555..20418
                     /locus_tag="ACOIAP_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGZ2637989.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETPEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLADSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20451..21593
                     /locus_tag="ACOIAP_001082"
     CDS             20451..21593
                     /locus_tag="ACOIAP_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HGZ2637990.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKSLEKKGIENTVVKCDYEGFLNYEDLEKAIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYNIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRAAVIALNIGNMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21729..22304)
                     /locus_tag="ACOIAP_001083"
     CDS             complement(21729..22304)
                     /locus_tag="ACOIAP_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HGZ2637991.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGNDTSKKETKSNTNVEQ
                     PKEENSTEKEVPNNKTKPTPKEETKTQSATIYSFDVDKTDLIENKVDLSKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAEALMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22564..23856
                     /gene="rstA"
                     /locus_tag="ACOIAP_001084"
     CDS             22564..23856
                     /gene="rstA"
                     /locus_tag="ACOIAP_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin production/motility transcriptional
                     repressor RstA"
                     /protein_id="HGZ2637992.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEITLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            23961..24563
                     /gene="yedF"
                     /locus_tag="ACOIAP_001085"
     CDS             23961..24563
                     /gene="yedF"
                     /locus_tag="ACOIAP_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HGZ2637993.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDKLEEGVVVTIVDNETAKENV
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNIVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24636..24899
                     /locus_tag="ACOIAP_001086"
     CDS             24636..24899
                     /locus_tag="ACOIAP_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HGZ2637994.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILIENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24914..25099
                     /locus_tag="ACOIAP_001087"
     CDS             24914..25099
                     /locus_tag="ACOIAP_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HGZ2637995.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25202..26398
                     /locus_tag="ACOIAP_001088"
     CDS             25202..26398
                     /locus_tag="ACOIAP_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGZ2637996.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDADGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26612..26890
                     /gene="rpsF"
                     /locus_tag="ACOIAP_001089"
     CDS             26612..26890
                     /gene="rpsF"
                     /locus_tag="ACOIAP_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGZ2637997.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            26927..27361
                     /locus_tag="ACOIAP_001090"
     CDS             26927..27361
                     /locus_tag="ACOIAP_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGZ2637998.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27380..27607
                     /gene="rpsR"
                     /locus_tag="ACOIAP_001091"
     CDS             27380..27607
                     /gene="rpsR"
                     /locus_tag="ACOIAP_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGZ2637999.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27750..28070
                     /locus_tag="ACOIAP_001092"
     CDS             27750..28070
                     /locus_tag="ACOIAP_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HGZ2638000.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28078..29034
                     /locus_tag="ACOIAP_001093"
     CDS             28078..29034
                     /locus_tag="ACOIAP_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HGZ2638001.1"
                     /translation="MNNKIRLSKAMSIIILAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFSDISYALNICIMYSLPGVVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNTFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSRLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29045..31039
                     /locus_tag="ACOIAP_001094"
     CDS             29045..31039
                     /locus_tag="ACOIAP_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGZ2638002.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRHHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31040..31489
                     /gene="rplI"
                     /locus_tag="ACOIAP_001095"
     CDS             31040..31489
                     /gene="rplI"
                     /locus_tag="ACOIAP_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGZ2638003.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRALGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31508..32836
                     /gene="dnaB"
                     /locus_tag="ACOIAP_001096"
     CDS             31508..32836
                     /gene="dnaB"
                     /locus_tag="ACOIAP_001096"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGZ2638004.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33041..33349
                     /locus_tag="ACOIAP_001097"
     CDS             33041..33349
                     /locus_tag="ACOIAP_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638005.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKSEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33431..34720
                     /locus_tag="ACOIAP_001098"
     CDS             33431..34720
                     /locus_tag="ACOIAP_001098"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGZ2638006.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKMDNISTENIKISNRA
                     HVIFPYHKELDVLSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAIRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35051..35126
                     /locus_tag="ACOIAP_001099"
     tRNA            35051..35126
                     /locus_tag="ACOIAP_001099"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35084..35086,aa:Lys,seq:ttt)
     gene            35133..35207
                     /locus_tag="ACOIAP_001100"
     tRNA            35133..35207
                     /locus_tag="ACOIAP_001100"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35166..35168,aa:Glu,seq:ttc)
     gene            35212..35287
                     /locus_tag="ACOIAP_001101"
     tRNA            35212..35287
                     /locus_tag="ACOIAP_001101"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35245..35247,aa:Val,seq:tac)
     gene            35321..35395
                     /locus_tag="ACOIAP_001102"
     tRNA            35321..35395
                     /locus_tag="ACOIAP_001102"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35353..35355,aa:Thr,seq:tgt)
     gene            complement(35777..36769)
                     /locus_tag="ACOIAP_001103"
     CDS             complement(35777..36769)
                     /locus_tag="ACOIAP_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2638007.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSLDDE
                     ISKIGLRLAKIVLLNPKSKDEIVKKTKENIESLKLKKEKLLTENNIPLDYLEIKFQCV
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKSSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDSNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36778..37836)
                     /locus_tag="ACOIAP_001104"
     CDS             complement(36778..37836)
                     /locus_tag="ACOIAP_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGZ2638008.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNSSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSVKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIIKACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            37961..39424
                     /locus_tag="ACOIAP_001105"
     CDS             37961..39424
                     /locus_tag="ACOIAP_001105"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGZ2638009.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNIEYINNTKSNIDKIYLHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSVGRFGYGENTINVTNWFPIVCVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLVNDKHDNKKMLYEIEAKNVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFRPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39509..40306
                     /locus_tag="ACOIAP_001106"
     CDS             39509..40306
                     /locus_tag="ACOIAP_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2638010.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     IDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTENDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSNAGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40319..42421
                     /locus_tag="ACOIAP_001107"
     CDS             40319..42421
                     /locus_tag="ACOIAP_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2638011.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     VYQEYLSSLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELDSYIEIFKTKWLFTSIIVSMTSSVLFVRLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNRMGTNLMSAL
                     LFIFLMHFMWFFGIHGGNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGFLLCLVIAIFLSEKRINVRKLAKIASIPAVFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYISTGSIRGSLLQLFNLCVG
                     VMIYIPFIKISQNRYTYMFKNNIENLTKLVKRYELTGEQPNFLNHNGKIGSISKMLAS
                     DLKFAMKRGEIEIFYQPQVNYNGDVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACVDLKKSEKLLRNSVKFSVNISPDQLDEPKLPEQIKNIISSNDINPNM
                     LGIEITEQVALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENMDQRDKLYRLGCEIYQGYYYS
                     KAIPFEEFIEYANQEREI"
     gene            42489..42968
                     /gene="rlmH"
                     /locus_tag="ACOIAP_001108"
     CDS             42489..42968
                     /gene="rlmH"
                     /locus_tag="ACOIAP_001108"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGZ2638012.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSSKEMEIIKDKEGKKILGKVKHNSYVIALAIDGKSLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43117..43428
                     /locus_tag="ACOIAP_001109"
     CDS             43117..43428
                     /locus_tag="ACOIAP_001109"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2638013.1"
                     /translation="MIKIMLSCSAGMSTSLLVTKMEIAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43476..43793
                     /locus_tag="ACOIAP_001110"
     CDS             43476..43793
                     /locus_tag="ACOIAP_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGZ2638014.1"
                     /translation="MDEKIIEISFNIIGYAGKGKGLAFEAIKEAKNGNIEKAKDLLKE
                     SKEVINKAHKYQTELIQNEASGNKTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44005..44706
                     /locus_tag="ACOIAP_001111"
     CDS             44005..44706
                     /locus_tag="ACOIAP_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2638015.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTSSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLDKDILLGRKRKTYDESDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            44927..46228
                     /locus_tag="ACOIAP_001112"
     CDS             44927..46228
                     /locus_tag="ACOIAP_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGZ2638016.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKATLDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVESVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISAALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSSHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGIIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46366..47460
                     /locus_tag="ACOIAP_001113"
     CDS             46366..47460
                     /locus_tag="ACOIAP_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HGZ2638017.1"
                     /translation="MERRLGISVYPEHSKMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILEISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATSTKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVDRYQVVFNVVAKEKTSEIEKTIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTNIFKRGDVVIGNDDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            47462..48595
                     /locus_tag="ACOIAP_001114"
     CDS             47462..48595
                     /locus_tag="ACOIAP_001114"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HGZ2638018.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSNMMNIDEDELKNAVKKYKDFVVGIKARMSK
                     SVVISNDIKPLKVAKRIKNELNLPMMVHFGSSPPMIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDVAMKSKDAEIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIINKVTKNAAKAISLKNKGLIKEGYDADLTIFDV
                     VDEEKELQDSLNKSVITSISIKPRAVVVNGEYLNIGKSIRENE"
     gene            48613..49722
                     /locus_tag="ACOIAP_001115"
     CDS             48613..49722
                     /locus_tag="ACOIAP_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HGZ2638019.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELVNKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTLKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRGGEIAIYT
                     RDYKANEGKIEIDIRSVTGGDLDIIYNKIKEIIEK"
     gene            49787..50527
                     /locus_tag="ACOIAP_001116"
     CDS             49787..50527
                     /locus_tag="ACOIAP_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HGZ2638020.1"
                     /translation="MNCTPQYYKNRVCLNVLAGSIKNAKEVYDACDGHILVGLLSKNY
                     STVEVAIEDIKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQDDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVHIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGDTKVEDIEVLYKIMKELLG"
     gene            50532..51524
                     /locus_tag="ACOIAP_001117"
     CDS             50532..51524
                     /locus_tag="ACOIAP_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGZ2638021.1"
                     /translation="MNILAFGEIMMRLSVPGYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANVRKLGVKDDFITYGGNHIGVYFLESGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEGMDVVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERSYDDLVNDYKKILPYCHGLFASCRDINKILNIDNLDIKSSSE
                     LIKKEFDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESKEYKLEIYDRVGAGDGYVA
                     GIIYSYLENMSNEDIVEFGVASSVLAHTTYGDNSLVSTSHVLRLMNNEKIDILR"
     gene            complement(51712..52593)
                     /locus_tag="ACOIAP_001118"
     CDS             complement(51712..52593)
                     /locus_tag="ACOIAP_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2638022.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKSLEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEHK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVASNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52866..54254
                     /locus_tag="ACOIAP_001119"
     CDS             52866..54254
                     /locus_tag="ACOIAP_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LVIVD repeat-containing protein"
                     /protein_id="HGZ2638023.1"
                     /translation="MEDKFYAKGKGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLVYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLIILDVEDLTRPKCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKSWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFLGPRLAVTEDIIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54282..55235
                     /locus_tag="ACOIAP_001120"
     CDS             54282..55235
                     /locus_tag="ACOIAP_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2638024.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSICVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNVIGTKVAEATGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTKLAQVRQLGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYIEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTPEFKERKTAYNFIEPLTKEKQAGASLR"
     gene            55288..55512
                     /locus_tag="ACOIAP_001121"
     CDS             55288..55512
                     /locus_tag="ACOIAP_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638025.1"
                     /translation="MNEKPSFKQIEIILVVICLVFAHYNVRLTPEFIAIIIPLYLSYF
                     IVSIIANQIAIKLLEIRQTREATSYNIGNG"
     gene            55505..56017
                     /locus_tag="ACOIAP_001122"
     CDS             55505..56017
                     /locus_tag="ACOIAP_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HGZ2638026.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMEYMNFNQNLELFLTLSILGFFAVVIAS
                     SFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAIAMAVGIWYVGVGVDLFTRY
                     ILSKDKKKLN"
     gene            56049..56903
                     /locus_tag="ACOIAP_001123"
     CDS             56049..56903
                     /locus_tag="ACOIAP_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HGZ2638027.1"
                     /translation="MVMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDIENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGVSKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVA
                     ELWFEGEEEWYKAVVEEAKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57529..58050
                     /locus_tag="ACOIAP_001124"
     CDS             57529..58050
                     /locus_tag="ACOIAP_001124"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGZ2638028.1"
                     /translation="MVLLIVDTQKLITNEELYNFNEFVVNLVKLIDTARKKYIEVIYV
                     RHDDGIDCELTKGKHGFEIYEEFKPCDEEKIFDKDVNSAFKETGLLEYLTNKNEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPSYANTTIDNSFMSAEQSYKYYNEFIWNGRYA
                     ECISLDETLKRMN"
BASE COUNT        22122 a         7130 c         9668 g        19342 t
ORIGIN      
        1 catctttaaa acagtaggtc aatacttttt tatatttttt tataaatttt tttcatattc
       61 ttttttcagc ttctctacta cctttttctc tagcctagaa acagtcattt gagatatccc
      121 taattcctta gctatactag attgtgtttt atcaaagaaa aatctatctt taaaaatttt
      181 aacttctaat tcatttaaag tttcaataaa cttattaata aaatcttcat actctatact
      241 tccaaagtta ccttcttctt taccaatctt atcaataaga gttatatctt tatcctctga
      301 atcatcatta cttgatgaat ccaaagacat tggttgatat ccataagaag cctccatagc
      361 ctctagaaca tcttcctcac taacgcctat ataatcagct atatctttta cctttggatg
      421 ctttttattt tcttgttcta atttaatctt cgcatcactt atctttttgc ttaattcctg
      481 tatccttctt gggactctaa gtgtccacac cttgtctcta aaatactttt ttatttctcc
      541 tactatagtt ggtgtcgcaa agctggagaa ctcaaaccct ttctcaacat catatctatc
      601 aatagcataa attaatgcca atgaagcaac ttgatatata tcttcaaaat caacaccttt
      661 gtttatatac ttcttagcta acaatcttgc taaatacaga tgtctttcaa taagaatatt
      721 cctaatatct acatttttat ttttattata taaattaaat agctcttttg tatccatatt
      781 taggtaatgt gtagcattag ctacattttt cattaaatat caactcctaa atatttagtc
      841 atttttattt ttgtcccctg attatgttct gattcaatat ctacatcatc cattaaagtt
      901 ttaattataa ataatccaag accactctct tttggattct ctaaatctgg tgtacttatt
      961 gagctaacat catatccttt tccattatct tgaatttcta tattaattgc attatctaaa
     1021 atattaaata ctatattaaa catatcatct ttactatgtt ttattgcatt tgtacatgct
     1081 tcagatactg ctacttttat atcttctata tcatctattg gaaaacccat cttattggca
     1141 attccagagg ctgttaatct tattatacta acataatctg gatttgtagt aatttccatc
     1201 tttatagtct cacaagccaa agtttatccc tccattttaa atattttatc tagacctgtt
     1261 atagtaaaaa tctttcttac attactctta ggatttacta tgtatatctc tttttcattt
     1321 atttttaatt tttttaatac acctatcata gctcctaaac ctgttgagtc tatataatct
     1381 agatctttaa gattaatctt tacatctaac atattctttt ctattaaacc atgtaagtgt
     1441 tcctttagtt tatctgctgt agaaacatca agttctccat caaggcaaac attccaaaat
     1501 ttattttgtg aatctaaatt tgaatcaata ttcatagaca tgtaaaaacc tcctatttcc
     1561 ttttaataat tttaaatata tttcctatac tcaatatttt attaattaca taaactatat
     1621 catctattcc ctttgatatt gatgatgcat tttcaacaat atcttgtata tgtctttcat
     1681 tataatctac aatcttatat gccttttcaa caactttatt tatgctattt agagttttag
     1741 ctaaataaat tgctactatg agagcagagc ttcctactaa cactgctcca atctgccacc
     1801 cccatgcatt cattagttaa catctccctc atcatcaaag cttttactta ttactatatc
     1861 ttcttctgaa atctttatat cttcttcatt attatcatcg tctactaaat ttattattct
     1921 ctctttaaca tcattaaatg tttcatgtag aacttctttt ggattttctt taacatcatt
     1981 aaacttctct tttgtttctt ttcttagttc agaacctttt ttgggtgcaa aaaacatacc
     2041 aaatataaac cctaaaatag ctcctaataa taaaaatcca ccttttttac aacttctttt
     2101 attgcacata acaattactc ctttcaattt taaattttta tctaactaca ttatacaaaa
     2161 agaataggat atttatccta ttcttcttca atatttattt tggcaatcga aactacatta
     2221 acttcatcat tcgtcttcat taatttaaca ccacttgtaa ctcttccaaa cagtgatatt
     2281 tcattgactc ttattctaat aagaactcca tcagaattta taatcattat ctcatcatct
     2341 tcattaacca tatctgcacc tacaattgta ccagtctttt cagagatatt ataagtttta
     2401 attcctttac cagctcttat ttgacttcta tactcttcta tatttgtcct ctttccaaaa
     2461 ccattcttac ttacaactaa cacatctgta cctttactgc aaaggttcat agacacaaca
     2521 aagtcttctt tacttaaagt tatacctttt acacccatgg ctgttctacc catatatctt
     2581 atatcatttt catcaaatct tatagacata ccttctttag ttactaaaag tacttcttgc
     2641 tttccgtctg taagttctac tccaataagc tcatcatcat ctcttaagcc tatagcaata
     2701 agacccgatt tatttatatt tttgaactct tccctcttag tcttcttaac aatacctttt
     2761 ttcgttgcaa gtaataaata ttcattttca tcattaccat caataggtat tagagtagca
     2821 attttctcat ctgctgacaa ttgaagtaaa ttcactatag cagttccttt agcctgtctc
     2881 ttaccttcag gtatttcata tgcatttaat ttaaatactc tacctttatt tgtaaagaat
     2941 aatagtctac tatgagtagt tgtagttact aagtgtctta caaaatcttc ttctctagtt
     3001 gtaagtgctg aaatacctct tccacctctt ttttgactct tataagtatc agatggaagc
     3061 ctttttatat atccaaagtg agtaagagtt attgctattt cttcatcact tataagatct
     3121 ctcatatcta tttcgccttc agcatgtctt atttctgttc ttctctcatc agagtaattt
     3181 tcttttatta ttgtaatttc atcctttatt acattcaaaa gtaatctttc atcagctaaa
     3241 atttctttta atctatttat cttcttgatt aagtcttcat attcagcttc tatcttatct
     3301 ctttctaaac ctgtaagtct ttgaagtctc atatctaata tagcttgtgc ttggatttca
     3361 gttaagttaa atttttctat taaacctaac ttagcttctt gcccagtctt tgaagctctt
     3421 atcaagctta taacagcatc tatattatct aaagcaatct ttaatccttc taaaatgtgt
     3481 gctcttgctt cagctttatt tagttcaaac ttagttcttc ttgtaacaac atcttcttga
     3541 tgtttaatat aatgatataa tatttgtttc agatttaaaa ctcttggctg accatctaca
     3601 agtgcaagca ttattatact aaaagtatct tccatttgag aatgtttata taaattattt
     3661 aatactatat tagcattagc atccctcttt aattctataa caattctcat accatttcta
     3721 ttactttcgt ctcttaggtc tgatatacct tctattctct tttctttaac taactcagct
     3781 attctctcaa ctagtttagc tttatttact tgataaggta tttctgtaac tattatttgc
     3841 tgttttcctt ttggtagttc ttctataaaa gctctagacc taactttaac ttttcctctt
     3901 ccagttctgt atgcttctgc tatactttct ttccccatta taattgcagc tgtagggaaa
     3961 tctggtcctt gaacaaattt tattaaatca tctacactac actctggatt atctatcaaa
     4021 tatacagttg catcaattac ttctgctaag ttatgtggag gtattgaagt tgccatacca
     4081 acagctatac catttgagcc atttactaat aaattaggat atctcgctgg caacactgaa
     4141 ggctctttta atgactcatc aaagtttggt ttaaagtcta cagtttcctt ttcaatatct
     4201 ctcagtagtt ctaatgataa tttactcatt ttagcttctg tataacgcat agcagctggt
     4261 gaatctccat caacagaacc aaagttacca tgaccatcta ctaaaagtgc tctagttgaa
     4321 aaatcttgtg ccattcttac catagcataa taaacagcag tatctccatg aggatggtat
     4381 ttacctaaaa cgtccccaac aatacgagct gacttcctgt atggtttatc tggagttaaa
     4441 tttaactcac tcattgaata tagtattctt ctatgaactg gctttaaacc atctctaaca
     4501 tcaggaagag cacgtccagc tatgacactc attgaataat caatataaga ttttttcatt
     4561 tcttccgcta tttcaatagg gagtattttg ttattttctt ccatgtatac taatcccctc
     4621 tctatatatc taagtttcta acaaatcttg cattttcttc tataaattct tttcttggag
     4681 caaccttatc acccataagc attgaaaata cttcatctgc aattgcagca tcctccacag
     4741 taacttgtaa taaagttctt gtttcaggat tcatagttgt ttcccataat tgctctgcgt
     4801 tcatctctcc aagacctttg tatctttgaa gttcaacacc atttcttcca atttcatcta
     4861 ataagatatt taactcttta tctgaataaa catagtgctc cttcttttgc tttgttactt
     4921 tatataaagg tggttgtgct gcataaacat acccttcatc tataagaggt ctcatatatc
     4981 taaagaagaa tgttaataat aaagttctta tatgggctcc atctacatcg gcatcggtca
     5041 taattataat tttatgatac ctagccttat ctatatcaaa atcttctcca ataccacaac
     5101 cataagctgt tatcatattt tttatttcat ctgaagataa tatcctatct agtcttgact
     5161 tctcaacatt aagtatttta cctcttaatg gaagtatagc ttgactattt ctgtctctac
     5221 cttgcttagc tgaacctccc gccgaatctc cttcgactaa aaatatttca cttttagctg
     5281 gatctttttc tgcacaatct gcaagttttc caggtaaaga tgtactttct agtacacttt
     5341 ttctccttgt taattccctt gctttttttg cagcttctct agctctttgt gctcttaagg
     5401 ctttatcaac tattattctt gctgttactg ggttttcttc taggaaagaa cctaattcat
     5461 caactgttac actatcaact atgcctctca taaagctatt tcctagcttt gttttagttt
     5521 gaccttcaaa ttgaggttct ggtaatttaa ctgatactac tgctgtaaga ccttctctta
     5581 tgtcttcacc aagtagatta acatcatttt ccttcaaaaa cttatttctc ttagcataat
     5641 catttacagt tttagtaaga gctgctttaa atccacttaa atgagaacca ccttcgtgtg
     5701 tatttatatt gtttgcaaaa gaatatatgt tctctgtata accatccgta tattgcatag
     5761 ctagttcgac aaaacaatca tcaacctttt tatctatata aactatgtca tcatgtatac
     5821 cagttctaga tttatttaaa tacttaatat attctaccaa accacctgta tagtgaaatt
     5881 cttttctttt ttcttgtcct tctcttttat cttcaaatac tatttttatt cctttattca
     5941 agaaagaaag ctctctaagt ctatattcca atgtttcata tttaaactct atttcatcaa
     6001 atattgtctc atctggcata aattgaatca ttgttccttt atcgtgagat tctccaacta
     6061 cttcaagctt agatgttggt aatcctttct catatgtttg cttatatatc tttccattta
     6121 agtaaacctc tgctaccatc cattttgaca atgcattaac tacagaaaca ccaactccat
     6181 gaagacctcc agatacttta tatcctccgc ctccaaactt tcctcctgca tgaagattag
     6241 ttaatactgt ttctaaagtt gatttgccag ttttaggatg tatttcaaca ggtatacctc
     6301 ttccgttatc ttttactaaa acactgccat cttcattgat agatacatat atgtctgaac
     6361 aatatccttg taaagcctca tctatactat tatctacaac ttcataaact aagtgatgta
     6421 aacctctagg gcttgtacta ccaatataca tacctggtct ttttctaacg gcttctaatc
     6481 cctctaatac ttgtatctga cttgcaccgt attcttgttt catttaattt cctccattct
     6541 ctatgctaat aacatcgcca ttttcaatat taaatattgt aacatttttt tcatcaaata
     6601 tttttttatg tgaaatctca gcacttgtta taaacatttg aacattgctt aaattattta
     6661 ctaaaagttt ttgtcttgct tcatctaact cactaaaaac atcatctaaa attaacactg
     6721 gatactcttc aacctcattt tttattaatt ctatctctga taactttaat gatattgaag
     6781 cagttctttg ttgaccttgt gaaccaaaaa gtcttgcatc taaatcattt atgaatatat
     6841 ttaagtcatc tttgtgtata ccatatctgg tagtcttaga ttctatatca ttaggcctat
     6901 tcgatgacaa cttggctaaa aatttattat atactgtatc tatagtatct tcgtcagtta
     6961 tatttatttg atttttgtat cgaattgata atctttcaac tccattagtc aaattcatat
     7021 gcatattctc agatatacta gctatctttt ttataaagtc tctacgcaaa atataaatat
     7081 aacttccata ccttgctaat gtatcatcat atacatctaa taaagcttca tcaacatgta
     7141 tacttttaag caccctactc ctttgagaaa gtgttttatt ataattggta agatatttat
     7201 aatatttagg tataatctga ctaatctctt tgtctataaa tgtccttctt tctttaggac
     7261 cctctttaac caacctcaaa tcctcaggag aaaatataac aacatttaag ttgccaagca
     7321 gttcttgtat cttttgcaaa ggaactttat ttactcttat ccccttttta tcttttccaa
     7381 taattagctc tattagacta tatttattat attttgaaaa acttcctcca atatataagt
     7441 tttcactatt aaatctaacc atttctttat ctttgttagt cctaaatgat tttccaaaag
     7501 aaagcatata aatagattct actatatttg tctttccttg accattttta ccaacaagta
     7561 gatttacttt cccattaaat tccagatgca actttttata atttctaaaa ttaacaagtt
     7621 gcaaactttt aagtttcaca aaaagttctc cttttttaca atacttttat tttagttcct
     7681 tctatttcaa ctatatctcc tgattttatc ttttttcctc ttcttaattc tatttcatca
     7741 tttactgtca ctaaaccttc ttgaattaaa aattttgcat gacctcctgt tgatgcaatc
     7801 tctgctaatt taagaaattg atctaacttt atatattctg attctatagt tatttcagtc
     7861 ataatagttc ctccttgtca ctattttaaa caaattccta ttgatacact aaaagtatat
     7921 tataccataa atatgcttat aaaaggagtt gtctaagatt agaaaaattt tctacaaaag
     7981 acaactcctt catgtctgct atatatttga tgatattctt actggaagca gtaagtaaat
     8041 ataattaaca tcatctgttg gtttaattat acaaggattt acatttgtag taaattctat
     8101 aaagatttcc tcattatcta tatttttcaa accttcaata aaatatctag aattgaaagc
     8161 tatgtctaga taatctccat ctaaatctat ttcaacctct tcatacacat ttcctttttc
     8221 tgtattagaa gtaattgcca ttaccttatc tcttatagat aactttataa gattattttt
     8281 ttctgactga gacaataaag acgctctctc tatactattt aaaagctcct tagtgtttaa
     8341 tttaactctg ctgttatgtt ctcttggcaa taacttttta taatcaataa aatctccttc
     8401 aagtaatctt gtgataattt tagtatcatt aattataaaa atagcatttt tttcgttaaa
     8461 cccaacttta acattatctt ctccagaaag caaactattt acatctataa gtgtctttcc
     8521 aggaattatg acttttatat tttcagttaa actatcaact gaacaacttt ttacagctaa
     8581 tctatatcca tcaattgcta ctaaatttaa gtttctatct acaatttcta aaagttctcc
     8641 cattaaaaca ggctttgttt ggtcctgtga gatagcaaat acggtttgtt taatcatatt
     8701 ttttaagatt tcttgaggta tactatataa atcttcttca tttaattctg gtaatttagg
     8761 aaattctttt gctgcatacc ctttaatttt aaatcttgaa tttacacaat ttatgtaaat
     8821 attattttct gaatcagttt ctatctcaac gaaagaatct ggtaattttc taattatatc
     8881 tccaaatagc cttgcatcta caacaacatc tcctttttct atgatttctg cttgtacata
     8941 agtttctatt cctatttcag catcatatcc agtaagtttt aattgacctt cttctgtaga
     9001 tataagtata ccttttaata attctattgt tgtttttcca ttaatagctt tttgagcaat
     9061 tccaattcta tttgctagga ttttttgatt acaaattatt ttcaatgtgg ataacctcct
     9121 ctggcttttt atatataaaa ataagttaaa atcatagtag taatagtagt aggtgttgtt
     9181 gataatgtta ataagtatgt ataacattat aaatacaaag atattaacat gtgtataaga
     9241 tgttaatatc tttgttattt tagacttgat aatttgttaa tactttttgt tcaaaaaaag
     9301 tattaacagg ttattcaaga gatataaaca tacaattgtg tataaattat cccttcaaat
     9361 ctgatataat tttgtctatt ttagtcttaa tttcttcact ttcttctata tccttagaca
     9421 ctttgtcatg agcatgaatt actgttgtat ggtctctacc tccaaactct tcacctattt
     9481 taggaaggga taaatcagta agttcgcgcg ttaaatacat agctatctgt cttggataag
     9541 ctattgaacg tgttcttttt ttagaattaa aatcttccat ctttaaattg aatacagaag
     9601 atactttttc ttttattctg agaacattta tttcttcatt tttagaagtt gttataatat
     9661 cttttaaagc ttctgtagca agatcaaaag atattaccct attactaaga gaagaataag
     9721 caactactct agttaatgca ccttctagtt cccttatgtt tgacttaata ttttttgcta
     9781 tatatgacat aacctcattt ggcacatcta tacgttctag ttgagccttt tttctaagta
     9841 tagcaattct tgtctcaaag tctggtgctt gaatatcagt tataagtccc atttcaaatc
     9901 tcgatcttag tctatcttct agtgtaggta tatcttttgg cggtctatca ctagatataa
     9961 ttatttgttt gtttgcttca tgaagagtat tgaatgtatg gaaaaactct tcttgagttc
    10021 tttcttttcc tgctataaat tgaatatcgt cgattaataa tacatctacg tttctatatt
    10081 tattcctaaa ttcttcgttt ttgtcgtctt ttatagagtt tataagttca ttagtaaatt
    10141 tttctgaaga aacgtaaact acttttgaat cttttttttg actaacaata tgatgaccta
    10201 tagcatgcat taagtgagtc ttacctaatc ccactcctcc atacaaaaaa agtggattgt
    10261 aagctttagc tggagattct gcaactgcaa cacatgcagc atgtgcaaat ctattgctat
    10321 taccaataac gaacgtatca aatgtgtatt ttggatttag attagggtaa agaactctat
    10381 aatttaaatc tgtactatca gaatttaaat cagcaacttc tttttcgctc aatacaaatt
    10441 taatattata tttttttaat gacagctgac taatagcatc ttcaattaaa tgtaaatatc
    10501 tattctctaa gatatcttta ttaaaatcac taggagccag taatattaaa tcattaagat
    10561 gtatttttaa tggtacgatg tttttaaaaa aggtattaaa acttaccgaa gttaagtcac
    10621 cttttattaa ttgtagggtt ttgtcccata aagaaactat atccataata taaacctccg
    10681 aacagaataa ttaatatttt ccacaaagtt attaacagaa aagcaaaaat atatataaat
    10741 tttacagaat aactaaattt atggataatg gtgttgataa attaataata gtataaatta
    10801 ttaaaaaaat atgaaaagat ataaacaata tgtagataaa gttataaata acataaacat
    10861 acaataaatg gtgattataa ctagagtatt gtcagtaatc ttaaaagtta tacacaaaag
    10921 tatccacaag ctgtgaataa tttctaataa gttgataaca tttatgcaca ttatcaacaa
    10981 gtatatttat aatatcaaaa tatatgtcaa acttcaatga tttgtaacta atttatccac
    11041 aatattaact aattgttgat aaaaatataa acatgttaaa attactttat ttgtgtatat
    11101 aattgaaaaa aataatttag aataaaatta aatagatttt tactagtatt ttcaataaaa
    11161 aaaatacata atatatatat ggtagatttt gtgatataag cgtcccaaaa actcgttgac
    11221 aacagtagta aaagtattta taattatatg tgttatgttt actttgaggg taaagttatt
    11281 atttttataa acggaaaata aaatctgaaa ggcggtgcaa aataatgagt aaaagaactt
    11341 atcaaccaaa aaagagacaa agaagtaaag aacatggttt cagaaaaaga atgaagacgt
    11401 ctaacggaag aaacgtgtta aagagaagaa gagctaaagg aagaaataga ttaactcatt
    11461 aattacaaaa gggccgctgc aaaggtggcc tttttgtgta aataattaca attcatagct
    11521 gtgtttatgg aggttaacta tggactttaa taggactaaa gggttgaaaa aagactctga
    11581 ttttagaaaa gtatataaac acggcaaatc ttttgcaaac aaatatttag taatatatat
    11641 acttaaaaat aaatcagatt atagtagagt aggtatttct gtttcaaaaa aagtaggaaa
    11701 agctattact aggaatagag taagaagatt aataaaagaa gtctacagat taaatattga
    11761 tgaaaaaatt aagcctggat atgatatagt atttatagca agagtatcta gtaaggatgc
    11821 tacttttaaa gacatagaca agtctataaa aaatttagtt aaaagaacgg atatttctat
    11881 ttaattgtat gctataaata tggaggttaa tgactttgaa taaaataatt tatatattaa
    11941 aggaaataag taggtattta tcgaatttat gtatttattt agtgagattt tatcaaaagt
    12001 atatatctcc cttaaaggga cctacctgta gattttatcc aacttgctca caatattcaa
    12061 tagaggcgtt taagaaatat ggatttataa agggtatgta tttaacgata agaagaattt
    12121 taaaatgtca tccttttcat ccaggaggtt acgaccctct aaaataaaag agagtaacta
    12181 ttaggaggta taaaaaaatt gaatataata ggaaatttct taggattgat tcttaaggta
    12241 atatttgaat ttgttaatca ttatggtatt tctataatac tttttacgat acttgtaaag
    12301 attattttat taccattgac aattaagcag actaagtcaa caaaggcaat gcaagatata
    12361 caacctcgta taaaagagat acaagaaaaa tataaaaata agccagaaaa acaaaatgaa
    12421 gaaattgtta agttatatgg agaagctaaa attaatccac tatctggttg tttaccttta
    12481 ttaatacagt ttcctatatt aataggatta tttagcgttt tgagagagcc agttgctcat
    12541 ggcgtttttg caaacaaagc tgcattttta gcagctgaca atgggttttt atggataaaa
    12601 agcttaacat caccagatta tatattggca gtattttcag gagcaagtgc atatgtcatg
    12661 caaaaagtaa tgacaccaaa agatcagtta caaggctcta tgaaagtaat gacatatgta
    12721 atggcaggta tgtctttcta ttggggattt atattcccag caggacttac attgtactgg
    12781 acagtaagta acttattctc aatagctcaa tattacttaa taatgaatcc tttaaaagct
    12841 aaactggctg ctaactctaa ggaggaaaaa gttaatgaga aaaagcctaa aattaataaa
    12901 aagtaagagt aaagaggaag ctataagtaa agctatagca gagttaaatt taaaagcaga
    12961 ggatatagag gtagaaatac ttgaaaatcc aagcaaagga tttttaggtt ttataggtgc
    13021 taaagatggt acttatgaaa tttttgttat cgagagggaa gtagatgtag ctaaaaattt
    13081 tatagaggta atgttgaaaa atgcaaatgt tgatgccaaa gtcaatgtat ctcaaaaaga
    13141 taatttaatc atggttgata ttgaaggcaa agaagctgca agtttaattg gtagaagagg
    13201 ggaaacttta gattctattc aatttttgac tggattagct cttaataaaa taaataaaga
    13261 ttctcataca agagtacttg tagatataga aaattataga tcaaaacgag aagaatcttt
    13321 aataagatat gctaataaag ttgctagaga agtagcgaaa acaagaaaaa ttaaaaaatt
    13381 agattatatg aatccatatg agagaagaat aatacattca gctcttcaaa atgacaaata
    13441 tgtaattaca tatagtgaag gaaccgatcc atatagaaga ttagtaattg agtgtaaaag
    13501 ataaagtcaa cctcctaaac attagggggt tttatttttt aatattatta aatcattaaa
    13561 gattggttaa atataaatct atatgtaaaa aattatgaat taagaggtga taaatttgtt
    13621 tatagatgat acaattgcag caatagctac agcacctgga gaaggtggta taggtatact
    13681 tagaataagt ggagaaagag ctttgaaggt tgcagaagaa atctttaaat ctatgtcggg
    13741 aaagagtatt gaagaataca ataagagaac attaatatat ggaaatatag tggataaaga
    13801 aaatataatt gatgaagttt tattggcata tatgaaagga ccaaactcat atacaggaga
    13861 agatgttata gaaattaatt gtcatggtgg atttatttcg gtaaagaaga tattagaact
    13921 aatactatca aaagatgtta gattagcaga agctggtgag tttactaaaa gagcattctt
    13981 aaatggaaga atagatttat ctcaagcaga ggctgtaatt gatgttataa aagccaaaac
    14041 tgatatagct catgaagttg ctcaaaatca attagagggc tctttatcaa agaagataag
    14101 agaattgaga gataaggtca ctgagatatt agctcatgta gaagttgcta tagattatcc
    14161 tgaagaagat attgagcata taacgtatca aactcttaaa gataaaactg atgaacttaa
    14221 aaaagaaatt aaaaaattat atgatacagc tgaaagtgga aaaatactta gagaaggttt
    14281 aaagacagta attgttggga aaccaaatgt aggtaaatct tcacttctta actccatttt
    14341 aggagagaat agagcaatag ttactgatat accaggaact actagagatg ttatagaaga
    14401 gtttgtaaac ataaaaggta tacctttaaa aattgttgac acagcaggta taagagatac
    14461 tgatgatatc gttgaaaaaa taggtgttga aaggtctaaa gaatcattta ctagcgcaga
    14521 tttgatagta atggttttag atgcatctag aaagttatca gaagaagata tagagatatt
    14581 agaaaaactt aaggataaac aaacaatagt gttgttaaat aagaatgatt tgaaacaaga
    14641 aattgaggaa gaaaaaatac ttaaatatgt agaaaataat agtataataa aaatatcagc
    14701 tttacaacaa gaaggaatag aagaattaca agataaaata gagtctatgg tatataaagg
    14761 tagtatcaaa aataattcta gtttagtagt aacaaattca agacataaag atgcacttag
    14821 taaagcatat aaatctgcaa cagatgcttt aattgctttg gaacaaagca tgccatttga
    14881 ctttgtagaa gtcgatttaa aaaatatatg ggactatctt ggatatatta atggtgatac
    14941 agtaacagaa gatttactag ataatatatt ccataatttc tgtattggta agtaatgtac
    15001 aaaagtaaat ttgtttttat tatagatatt ttttaaaaat ttgtagtgtt tctcatgaaa
    15061 cattaatttt aaacagaaag gaattataaa tgataaagtt tgaagcagga aaatatgatg
    15121 ttatagtagt cggagcagga catgctggat gtgaagctgc tttggctact gcaagaatgg
    15181 gatataaaac tttgataata acaatgtctt tggattctat agcattaatg ccttgtaatc
    15241 catcgattgg ggggactggt aaaggtcaat tagttaaaga aatagatgcc ttaggtggtc
    15301 agatgggact aaatatagac aagacatata tacaaagtag gatgttaaat actgctaaag
    15361 gtccagcagt gcactctttg agagcacaag cagataaatt taaatatcat gaagaaatga
    15421 aaaagacatt agaagatgaa ccaaaccttg atatagctat ggatgaagtt gtagaaatac
    15481 ttcacgaagg aaatgttgta ataggggttg gaactaaact aggatgttca tttaaatcta
    15541 aagctgtaat attggccact ggagtttatc ttaactcaaa gatatatatg ggtgaagttg
    15601 cattttatga aggtcctaat gcactgggtt atgcaaaata tcttacagat agcttagttg
    15661 agcttggtct tagaatgaga agatttaaaa caggaactcc agcaagagtt catagagata
    15721 gtatagactt ctctgtaatg tctttacaag agggagatga aaaagtaact ccattctcat
    15781 ttatgaatga aaatatagaa aaagaacaag aaccttgtta cttaacaaga actacagaag
    15841 aaactcaaaa agttatacta gataatttaa aaagatctgc tatgtatagt ggagtaatag
    15901 aaagtactgg tccaagatat tgtccttcta tagaagataa agtagtgcga tttagtgata
    15961 aaacatcaca tcaactattt atagaaccag aagggttaaa cactaaagaa atgtatatac
    16021 aaggaatttc aactagctta ccttttgaag ttcaattaga tatgtacaaa actataaaag
    16081 gacttgaaaa ttgtaagata atgagacctg catatgctat tgaatatgat tgtgttgacc
    16141 caactcaact aaaaataagt ttggaaataa agggcgttga gaacttattt agtgcaggac
    16201 agttcaatgg gacttctgga tatgaggaag cagcagctca aggacttatg gcgggtataa
    16261 atgcagttag aaaaatagaa ggaaaagagc catttgtatt agaccgttca gaagcttata
    16321 taggtgtctt attagatgac cttgttacta aaggaactaa cgaaccttat agaatgatga
    16381 catcaagagc agaatatcga ctatatttaa gacaagataa tgcagatatg agattaactc
    16441 aaaaaggtta tgatatagga ttagttaaaa aagatagata tgaaagattt ctaaataaaa
    16501 aggctgctgt agagaaagaa tttgaaagat taaaaaatga aagagttaca ccgaaagaag
    16561 taaatagttt gctagaagaa aagggagcaa caccaataaa ggttggaata tctctatatg
    16621 aatttttaaa gagaccagag gttacttacg aattgcttga agaattagga aaaggcgctg
    16681 gagaagatgt ttcaagagaa gttaaagaac agtgtgtaat aataactaaa tatgaaggtt
    16741 atatagagaa acaattgaaa caaatagacc aatttaaaaa acttgagaat aaaaagctgg
    16801 atgagaaaat aaattattca tctatagaag gtcttagatt agaggctaga cagaaattgg
    16861 atgatataaa acctatttca ataggtcaag catctcgtat atctggtgtt tccccagctg
    16921 atatatcagt tttacttata tacctagaac aagtcagaag aactagaggt ggcaaaggtg
    16981 aataatatgg aacttctgaa aaatgggatt gaaggtttta atatagatac gaatgatagt
    17041 atgttagaaa aatttaaaat ctatagagag atattaattg actggaataa aaagatgaat
    17101 cttactggaa tagaggatga aaaagaagta tatataaaac attttttaga ctctatttca
    17161 gctgtaaaga atggatatat aaaaaatggt atgtctataa tagatgttgg tacaggtgct
    17221 gggtttcctg gaataccatt gaaaatatgt ttagatagat tagaacttac tttgttagat
    17281 tcgttaaata aaagaataaa ctttttagag gaagttagta gagtattaga gttagataat
    17341 attaaattta tacatggaag agcagaagat tttggtaaaa atgaaaacta tagagaaaaa
    17401 tatgatgttg ctacagcaag agctgttgct ggattaccaa ttcttatgga attttgtgta
    17461 ccctttgtaa aagttggagg atattttatt tgcttaaaag gtccaaatgc taatttagag
    17521 ttagaagaat ctcaaaaggc tattgatgtt ttaggcttag agtatattga aaaaatagat
    17581 gtagaactac cagaaataga tttaaatcat aatatattag tttttaaaaa agtaatggaa
    17641 acaccagtta agtaccctag aaaggctggt aaaccagcta aaaatcctat taagtaatga
    17701 aaaaattatt agcggtaagc ttaattattt ctcaggaaat aattaagctt atcgtaaaaa
    17761 aacaaaaata aaggaattat taaagtagat gcagaaataa atttgtatgt acatatagag
    17821 aacaaaaata atttatatct aaaataagag aggtatgtta tggaagataa aagagttatg
    17881 gagataccta tagaagatgt agttccaaat ccatatcaac caagaaaaat attttcacaa
    17941 gtttcattgg aggaattgag taattctata aaggtatatg gtataattca acctataaca
    18001 gttagagcaa aagatggcaa atatgaacta attgcaggag aaagaagatt aagagcagct
    18061 aaattagcag aacttaaaac cataccagca attataaata atatgaatga tgaatcttct
    18121 gctgttctag cgttattaga aaatttgcaa cgagaagact taaatttcat tgaagaagca
    18181 attggttatg aaaacttaat aaaagaacat gcttttactc aacagcaatt agcagaaaaa
    18241 ttgggcaaaa atcaatctac tgtagcaaat aagcttagaa tattaaagct tccaaacgat
    18301 ataaaaatga agctaataga gaataattta acagaaagac atgctagagc atttcttaaa
    18361 ctaccaagtg aagatttaat gcaaagtgtg ttagacaaag tcataaaaaa tgaattgact
    18421 gttaaaaaaa cagaaaaatt gatacaagat gtattagaag aaactaaaat tcaagaagag
    18481 cctgataaaa aacagaatat aaagggtgct atgagtataa gaatttacat aaatactata
    18541 aagcaggcct ttgatgctat atcaaataca ggaattgatg ctaagtataa tgaaatagat
    18601 aagggagatt atatggaggt tgttgtaaaa atccctaaaa aatagagatt actgcttacc
    18661 agtaatcttt ttttgtaata taagccttgt aatataaatt gatttataga cattatttat
    18721 acttaaaaaa cacctattca acatttaaaa ttaatttaat tcttaaaggg gggaacatca
    18781 tgggcaaagt tatagctgta ttcaatcaaa agggtggagt tgggaaaact acaacaaatg
    18841 taaatttaag tgctagttta ggaactttag gaaagaaaat attagtatta gatttagacc
    18901 cacaaggaaa tacaactagt ggatatggta ttaataaaaa tgaagtagaa aatacaatct
    18961 atgaaattat gttagatggg ttacatatta aagaagcaat aataagtact gaatttgaga
    19021 atgtagatgt agttccatca gctactgaac tatcaggtgc agagatagag cttacatcta
    19081 aaactaatag agagtatatt ttaaaaaatt ccataaaagc agtaatagat gaatatgatt
    19141 atatattttt agattgtcca ccctcactag ggatgcttac aataaattgt ttaactgctg
    19201 tagatagtgt tttaattcca atacaatgtg aatattatgc tttagaaggt gttagtcaat
    19261 taatggagac tataaaatta gtaaaatcaa gactaaatgc tgatatagaa attcaaggtg
    19321 ttgttttaag tatgtttgat ggaagagcta acttatcaat acaagtagtc gaagaagtca
    19381 agaaatactt taaagggagt gtatatacaa ctctaattcc aagaaatgta agacttgcag
    19441 aagctccaag tcatggaaaa cctgtaattt actatgataa aagatgtaga gggtctgtag
    19501 cttatttgga actagcagaa gaatttatag atttagaaga ggaggaatgg tagtatggag
    19561 aataagtcta aaagaagtaa tagattgggt agaggtctta gtgcattgat accagaaatt
    19621 aaaggagaaa ctccagaaaa agaaatagtc aacatagata tagacaaaat atatccaaac
    19681 gaagttcaac ctagaaagca atttgatgaa gaaaagataa aagtattggc tgactctata
    19741 aaaaattatg gtgtattaca gccaatagta gttaaaatgg atgaaaataa taaatacatg
    19801 ataatagctg gagaaagaag atttagagca tcaaaacttg caaataaaaa tcaaatacct
    19861 gctataatta aagatataga tatgaaagat ataatggaga tagctttaat tgaaaactta
    19921 cagagggaag atttaaattc aatagaagag gctctagcat ataagagttt aatagaacat
    19981 tacaatgtaa ctcaggaaga gatatcagaa gctgttggta agagtagacc tcatataact
    20041 aacacactaa gacttttaaa tcttggacaa gatgttatag aaatgataga cagtggtaga
    20101 attacagcag gtcatggtaa ggctttattg agaattgcag ataaagattt gcaacttcaa
    20161 atagcaaaaa aaatagaaga agaagaactt tctgtaagag aagttgaaaa tatagctaaa
    20221 aaaatatctg aaaataaaca agaagaaccg aaaaaatcta aacctaagga tgtatttatc
    20281 ttagatgttg aagataaact tagaaatata tttggaacaa aggtgaatat ctctaaagga
    20341 aagaaaaaag gtaaaataga gatagaatac tataatgatg atgatttaaa tagtattgta
    20401 tcaatgcttc ttgaatagaa caaaaatata aaacagagag gaagattgtt atgatttatt
    20461 tagataatgc tgcaactaca tatccaaaac cagaaagagt gtataatgct gttttagatt
    20521 gtatgaaaaa ctattgtgca aacccaggta gagcaggtca taaacttgct atgagagctg
    20581 ctagggagat atatgacaca agagagaata tagctaagtt gttcaatgta agtaatccta
    20641 tgaatatagt atttacatct aatgcaacag attctttaaa tttagcaata aaaggcgtat
    20701 tacaagaagg agaccatgta ataacaacat ctatggaaca taattcagta ataagaccta
    20761 taaaatcatt ggaaaaaaaa ggtattgaaa atactgtagt aaaatgcgac tatgaggggt
    20821 ttctaaatta tgaggattta gaaaaagcga taaagagtaa tactaaattg attgtaacaa
    20881 cacatgcatc taacgtatgt ggaactttaa tagatataaa aaaagttgga gaaatagcta
    20941 aaaaacataa tatactattt ttagtggatg catcacaaac agcaggtgtt tataatatag
    21001 atgtaaatga atgtaatata gatatgttgg caatgccagg tcataaatgc ttatttgggc
    21061 ctcaaggaac aggtatatta tatgtaagag aagggttaaa cttaaatata ttaaaagaag
    21121 gtggaacagg tagtaaatca gaagaaatag ttcaaccaga gttattccca gataaatatg
    21181 aatcaggaac tcataatact ccaggcatag caggtcttaa ccaaggtata ttatttatat
    21241 ttgaaagagg aatcaacaat ataagacaac atgaagaaga attatgtcaa tatatgatag
    21301 acaaattaga ggaagtccca gatataaaga tatatggacc aaaagatagt aaaaaaagag
    21361 cagcagtaat agctctaaat ataggaaata tggattctgg agaggttact ttcttattag
    21421 acagtgatta taatatagca accagatcag ggatacattg ctctccacta gcacatacca
    21481 ctttagggac tttaaaacaa ggagcagtaa ggtttagtat aggatatttc aacacaaaag
    21541 atgagataga taaagcagtg gaagctttga aaaaaatttc taaaaataaa tagcatgaaa
    21601 tttaagaata tataaaaata aagaaaggag atgtttcaaa ataaaaattt gaatcatctc
    21661 cttttttgta caaaaaagaa aaggggttcc taagaatccc taatctattt gataattgtt
    21721 tcaagaaatt attttaagta atctccttct tcaagaacta tatgaccact ttcataatta
    21781 gaaccatcaa cagtgatttt tatttgttca acattcatat tttttatgta agtacgagca
    21841 actgaatcaa gcattaaagc ttctgcatca ctacctaaat ttgactttgt aaaatcggag
    21901 ctaacatcta atataccagt ttttacacca tcaatgtctt ttgtagtaaa tgaatttaat
    21961 tttgcagatt ctggaacaac tttaagtttt tgaagttctt caaataaagt gttttcatca
    22021 attttactta aatcaacctt gttttcaatt aaatctgtct tatctacatc aaaagagtaa
    22081 atagtagctg attgagtttt agtttcttct tttggagtag gtttagtttt gttattagga
    22141 acctcttttt cagtactatt ttcttctttt ggttgttcaa catttgtatt actcttagtt
    22201 tcttttttag atgtatcatt tccattttga gcattagtac aaccaactgc gaatatagat
    22261 atagataata tacttaacac taacattatt ttcttatttt tcataaaaat ttctcccttc
    22321 ttaaaaacta ttcttatata taattatagt cgttatgagc aaatatatga atacaaaata
    22381 gtaacaaatt taaaaaatga tttatttaaa ttaattaaat tcaaaataaa ctaaatttta
    22441 gtcattttta tgggaaatca tttaatgtac actgaaaata ttgtaaaata aaagtagtgt
    22501 ttttaaaata aatataagtt ataattatat tataaaaaaa tgtcttcaaa aggtgggaat
    22561 agtatggaaa ttttgagctt aggagaaaag attaaaaaat taagaaaaga aaaaaacatg
    22621 acattaaaag aattagctgg agataggata acagcagcac aaataagcca tatagagagg
    22681 gataaatctc atactagtta tgaactgttg gaatatctag gcgataagct agatgtaagt
    22741 gtagaatatt tattagagac caaggaaatg caatcaaaaa agataactga taatttaata
    22801 ctacagagcg aaatttatat aaaagaaaat gagttaaaca aggctgagga ccaaataaaa
    22861 gaagttttag atatatgtaa gagatacgat ttaatggaga actatggcag atgcaatttt
    22921 ttaatggcta atattaatct gaaaaaatct aattataatg atgctataga aaactttgaa
    22981 aaggcattgt acttctttat aaaaaatagt gatagtgaaa atatacttaa gtgttattta
    23041 aacataggga aaatatatat gcaggaagac ttttataaag gtgctataag ccactttaat
    23101 tttgcagagg aaattttgtc agagaataaa tttgaggatg ttaacataca caaggaacta
    23161 tatagtaaga tggcatattg ttacataaaa ctagataatc caaatatgtc attgaaatac
    23221 atagaaaaaa taaatgaaat agataataga aatgatagaa aagaagatgt cgatattttg
    23281 gtattaaaag caaataatat gcttgaaatt gggaaatatg aggaatcaag agattacttt
    23341 aaaaaagcgc taaaaatact tgaaagtgaa gataataaaa ctggattagc aaatgtgtat
    23401 ttaacaattt gtgacgttta cagaaaaata ggtgaaacag atagagtact tgaatattca
    23461 caaaaggtat atgacataaa gaaaaatgat gaagatgaat atatgatgtc aggattattt
    23521 aagataatag aagcatatat agataaagaa gattatgatt tagctagaaa atattgtaag
    23581 atagccttag cttcatcaat aaaaaataaa aataaattca atgaatataa agcattgaga
    23641 ttctatgcta atatgtataa aaatcaaaat gaaataactc ttgcaattga atatttgatt
    23701 aaatgcataa aaatagtatc agatttagga aacaatagaa tattggccaa tttatatata
    23761 gacttaggtc aattatattc aaatatatca aaagaaaaag agttagaata ttatcaaaaa
    23821 ggtgtattta tgtacaaaaa cttagaaata atgtagagta aataaaccta taagggtata
    23881 gaaacaatct ataacaagca agataatatc tatgataaaa tataaattgt atgaatattt
    23941 ttaaggagat gaatcagaca atgagtataa aaatagatgc aagagggctt gcttgtccta
    24001 aaccagttat aaatacaaaa agagaattgg ataaactaga agaaggtgtt gtagttacaa
    24061 tagttgacaa tgaaacagct aaggagaatg tattaaaact tgccaaatct ttaagttgtg
    24121 aagcaaatat tgttgatgaa aaagagaatt ttatatctat agaaattaga aaaggtaaga
    24181 atatactaga taaacaaaat attgtagata ataaagaaag tgaattagac aatacatgta
    24241 tatttatatc ttcagataag atgggacttg ggaatgacga attaggaaaa gtgttaataa
    24301 aaggatttat atatacatta acagaatcta aaccttatcc taagtatgta cttttagtta
    24361 atggaggagt aaaattaagt gctgaaaatg aagaaactat agaaaatcta aaaatacttg
    24421 agaatatggg tgtagaagtt ttatcttgtg gtacttgctt agattattat aatttaaaag
    24481 ataaattaca agtaggtaca gttacaaata tgtatactat agttgagaca ttaaagaatg
    24541 catcaaatac tatttctata taatgtattt ttgtttagta atataaaact aataataaag
    24601 attaactcaa atagatagtc agaaaggatt aagtaatgaa tcaaatgtat atagtgtcat
    24661 ttaattcgac acatcatgcg ataagatcag aaaagttatt tggtgaaaat agtctaaaag
    24721 taatggctct tccaacacca agagaaataa cagcaagttg tggaatatca attaaatttt
    24781 cttttgaaga tatggaaaag ataaaaacta ttttaattga aaataatgta gatataaaag
    24841 gaatttattg tataagtaaa ttagaaaatg gttcaaaaga agtagagaag ttagattagg
    24901 aggctaatta tttatgccaa tggatttaaa aataggtgat attgttgaat taaaaaagca
    24961 acatgcatgt gggtgtaaag agtttgaaat cataagaaca ggaatggata taaagataaa
    25021 atgtactaaa tgttcaaggc taataatgct tgatagagag accttagaaa agagagtaaa
    25081 aaagctaata aaaaagtgat aaaaatttaa cacttaaaaa atgtcaaata ccgtatatta
    25141 atatccaaaa ttttggtata ataagaattg aagaaaacat tttcatgggg gtgctttaat
    25201 tatggcagtt aaatatgcaa aaagaatgca aggtttacaa ggatcagaaa tacgtgagct
    25261 tttaaaactt actcaacaac cacaaataat atcttttgct ggtggaatgc cggctccaga
    25321 gttatttcca gttgaggaaa tgaaaaaagt atcagttgca gtgcttgaag aaaatggaag
    25381 atcagctatg caatatacta caacagaagg atatgaacca ttaagagaaa aaatagcagc
    25441 tagaatgaat gataaaaaca aaactaatgt aaacaaagat gatatattag ttacaagtgg
    25501 ttctcaacaa ggtctagatt ttgcaggaaa agtatttatt gatgagggtg atgtaatttt
    25561 atgtgaaagc ccatcttaca taggagctat aaacgcattt aaatcttacc aacctaaatt
    25621 catagatgtt ccaacagatg ctgatggaat gataatggaa gaattagaaa aaatactaga
    25681 aacaactgat agaataaaaa tgatttacgt aatacctgac ttccaaaatc caacaggaag
    25741 aacttggcca cttgaaagac gtaaaaaatt catggaaata gtaaacaaat ttgaaatacc
    25801 agtaatagaa gataatccat acggagattt aagatttgaa ggagagactt taccatcttt
    25861 aaaatcaatg gatacaaaag gattagtaat attcttagga actttctcta aaatattctg
    25921 tccaggatac agattaggat ggacttgtgc ttctccagaa attttatcta aatttaactt
    25981 tgcaaaacaa ggtgcagact tacaagcatc aactatatct caaatggaag taagcaaatt
    26041 tatggatatg tatgacttag atgcacatgt tgacaaaata aaagcagttt atgttaaacg
    26101 tagagatgta atgcttaaga ctatggaaga agaattccca gaaggattag tatttactca
    26161 tccagaaggt ggattgttta catgggtaga gcttccaagt aatttaaatg ctaaagaatt
    26221 aatgccaaaa tgcttagata agaatgttgc ttatgttgct ggaggaggat tcttccctaa
    26281 tggtggtaga gaaaatactt tcagacttaa ctattcaaat atgccagaag aaaaaataat
    26341 agaaggtata aaaaatatag cagctgtatt aaaagaagct atgggtgtag aagcttaatt
    26401 aaaaataata acttatatat aatacaaggg atggttattg ccatcccttg tttgtttgaa
    26461 aaatatataa tctaccttac actaaacttt gtccaaaatt taaattgaca gaaataagaa
    26521 taaatgataa aatgtgtagg tatgagattt tagtctcatt tctctgctct aagagtgtag
    26581 agccgttaag tccaaaggga ggtgaattat agtgagaaat tatgaattag tttatgtggt
    26641 aaagccaaac tctgatgaag aagtaagaga ggctatacta aacaaagtta aggaagttgt
    26701 tgcaactgac ggagaaatag ttaaagttga tacttgggga actaaaaaat tagcttatcc
    26761 aatagctaag tttacagaag gtttctatgt attagttaac ttcaaatcag cagtagacgt
    26821 tcctaaagag atagacagaa acttaaagat aaatgaaaac gtaataagac acatgatagt
    26881 tgttgcttaa taactggttt tattataaaa aataggtggt gtttttatga atcaagttgt
    26941 attagtggga agattgacta gagaccctga attaagatac atcccaggta caggaacacc
    27001 agtggcatcc tttacaatag ccattgatag agactatgta aaaaaagatg gatctaaaga
    27061 aactgatttt atacctgttg aagtaatggg taaatctgcc gaattttgtg ctaactacat
    27121 aactaaaggt agattagtag cacttcaagg atctataaga gtagacaatt atcagacaca
    27181 atcaggtgaa aagagaactt ttacaaaagt aagtactaga tcagtacaag ctttggatag
    27241 taagaataaa tcggaaaatt catatagaga gagtgctcca gcttttgagc caagctttga
    27301 acctcaaggt ttagacccac aaggtttcca agctatagat gatgacgata taccatttta
    27361 aaaaggaggg aaaaaagtca tgatgaataa aaaaagacgt aagaaaaaaa gagtttgtca
    27421 attttgtgct gacaaaaacg ctaaaataga ttacaaaagt actcaaagat tacaaaagta
    27481 tataactgaa agaggaaaga tattaccaag aagaatatct ggaacttgtg ctaagcatca
    27541 aagagaatta acagttgcta taaaaagagc gagaaatata gcacttttac catatacatt
    27601 agactaaaaa aatgagcctt gtgctcattt tttattatat ggatttatat atctaaatga
    27661 ggcgagctat aaagctcgtt tttttgttta tatacttaaa tatattatta tttatgatat
    27721 aatattatat attaaggagg gttgtaaacg tgaaaataga taaaggttct gagataacaa
    27781 gaaacataaa gataatagaa tggatgaaaa cagaaatatt aatgagtgta agtgatttgt
    27841 ttaatttatt gtttaaaggg gtaaaaccat tagatgaagc aattcaagat actttagcaa
    27901 atataataat gataacatat ctcttagcca agagattagg aatcagtttt agagatgtgg
    27961 attataaagt caaggaaaaa ataaaaattg gtatagatga ggaccatagt gttgaaagat
    28021 ggtatggaga tttatctaat ttaaaaaaac atatggataa tagggagtga tattaaattg
    28081 aataataaaa ttagactatc taaggcaatg tctataataa ttttagctat aataatcgct
    28141 ttagtaatag cctatattcc aatgctagga atatttagta tgttagcagc tgttccatat
    28201 gtaattatag gtgctattac tgatagaaag tattctctta tatctatttt ggttacattt
    28261 tgtgtactga ttctcttttc agacatttct tatgcattaa atatatgtat aatgtattct
    28321 ttaccaggtg tagtaatagg aaagatgcta aagagaagtt ttgaacaaga ggacagtaat
    28381 aaattcgaac cgatatatgg tggaaccata atatttgtac tttcaatgct tgtatatttt
    28441 tttgtattaa agacattttt aaatgtgaat ctattagatg aagtttctaa gatgatatca
    28501 gaaattgtaa atattcaaaa aaatactttt tctgcaaccg agcttaaagt gtttgataaa
    28561 atgaagccag atgagattgt aagttatttt acaaatatgc taccaatgat gttattttta
    28621 caagggttgc tatcagcgtt tgtcacatat tatttgagtg tattttttat aaaaaggatt
    28681 acaaagatga atataagatt tcctaaattt gctgattttt atttaccggg aaatgctata
    28741 ctcacaactt tcttacttta tttattggtc ttatttattc aaattattgg ttcaagacta
    28801 tacacagaat tgataatgac taatttacag ctagttttta atttaatgtt tgtaattcaa
    28861 ggtatagcag tttgcattta ttttttaaag aaatggataa gacagggacc aaataaaatt
    28921 atgttttttt cagggataat tttatgttta tttggattta tgggaatatc ttttgttggt
    28981 atggtagata gtataattga ctttagaaag gtaagaagct ataaatccac ttaggaggat
    29041 agaaatgagt aataaacaaa cctttaaatt aaatatgcca gaaataaatt tatatataat
    29101 tgttattggt atttctagta taattttgct ttattacaac ttgtatgtag ggtgtttatt
    29161 tttctgtatt tttgtatata tggttttcca taattggaga acaactaata tcagacatca
    29221 tgaatggaca gagtatattc aaaatttatc tttagatata gatgaaacaa ctaaaaaagc
    29281 cataataaat cttccaatac cattatgtat tttagaattt gatggaaata tatcctggta
    29341 taatggaaag ttttatgata tgattggtca aaaagattta ctagataaaa atatagaaga
    29401 tatagttaaa aatcttaatt taagaaaagt attaaatgaa aataaagaga tgtacacaga
    29461 aataaactat aaagaaaaag aatatacaat aatttataat gttataaaaa atgatcaaga
    29521 aaaaaatcct aaatatttga tgatattata ctggatagat aagactgaat atttaaaagt
    29581 aaaacaaaat tatgatgatg aaaaaaatgc aatgatgcta atacaagtag atggatatga
    29641 tgaagtatta aaaagtgcag cagaagataa gagagcttta attaacgttg aagtagagaa
    29701 aatactttct gctttagaat taaattcaaa tggtgcattg agaagaacct caaaagacaa
    29761 attcttcttg gtaatgcata aaaaagagtt aaaaaaattg gaagctgaga agttttctat
    29821 tttagataca ataagacata ttgattatgg aaataatctt cctgttacta taagtatagg
    29881 aattggtata gatggagata cattaaatga gaacctaaaa cttgctacag gtgctctcga
    29941 tttagcactt ggtagaggtg gtgaccaggc tgttgtaaaa acaaaagata aatttgtgtt
    30001 ttatggagga aaatctaaag ctgtagaaaa gaagaccaag gtaaaatcta gattaatagg
    30061 tcatgcttta agagaggtta tacaacaaag tgaccaagtt tatataatgg gacataaata
    30121 tcctgatatg gatgctatgg gagcagcagt tggtgtttat gatatatgta aatcatgtaa
    30181 caaaactgca aacatagttt tacaatctgt aaatgaatct atagaaatat ttataaataa
    30241 aataaatgaa aataattact ataaaaaatt gtttattggg aaagaggagg ctattgacaa
    30301 ctgtactaaa aatacattag ttgtagtagt tgatactcat agacctaatt atactgaatg
    30361 tgaagagcta ttaaagctat cagaaaaggt agtagttata gaccatcata gaagaggtgt
    30421 ggagtttata aatgatgcag tgcttttatt ccatgagata tatgtatcct caacgtgtga
    30481 aatggttaca gagttagttc agtatatgga tgaagatgta acaataaata aacttacagc
    30541 tgaaggactt ttagcaggta taagtctgga tactaaaaac tttgcattca aaacaggtgt
    30601 taggactttt gaagctgctt cttaccttag aaaagttgga gcagatacta tagaggtcaa
    30661 gaagttcttc aactctgatg taaaagactt cataataaaa gctgaaataa ttcaaagtac
    30721 taaaataatt aataatagaa tatgtttagc atattcaagt actgagatag atagtataaa
    30781 tgttataata gctcaaactg ctgatgagtt actaaacatc aaagaagtag aagcttcctt
    30841 tgtattaggt gaaaaagatg atactatatt tataagtgcg aggtctttag gacaaataaa
    30901 tgtacatgtg cttatggaaa aattaggagg cgggggacat atagacatag ctggagcaca
    30961 gttaaaaaat gtttctctaa aagaagctta taagatggta aataaaataa tagaggagta
    31021 tttggaggag gaagaataga tgaaagttat attattaaaa gatgtaaagg gaactggtaa
    31081 gaagggagaa atgaaagaag taagtgatgg atatgcaaga aatttcttat ttcctaaaaa
    31141 gatggctgtg caagcagata gtgtagcaat aaaagaatta aatgaaaaga ataaatctaa
    31201 agaaataaaa gcacaaaaag agtatgaaga agcagtttta ctaggtaagc aaatggaaga
    31261 aattaatata gaaatatatt caaaagcagg agaaggtgga agattatttg gttcaataac
    31321 ttctaaagaa attgctgaac aattaaagaa acaaaaagat atagatgtag ataaaagaaa
    31381 aatattatta gatgaaccaa taagagcttt aggttcaact tttgtagaaa taaaaataca
    31441 tcaaaaggta actactaaaa taagagtgga tgtaaaagaa aaacagtaat aattagaggt
    31501 gattaagatg gaagatatga cgagaattcc tcctcatagt gtagaatcag aacaatcaat
    31561 attgggttct atacttttag ataaagatgc tataataacg gttacagaaa ctataaagcc
    31621 tgatgatttc tataaagaag ctcacaaaat aatatatgaa tgtatgataa ctttaagtaa
    31681 taaaggtgag cctatagact tgataacatt aacagaagaa ctaagaaaac aagggcatct
    31741 taatgatatt ggaggaatca gttatattac aagtctttct actatagtac cgacgacttc
    31801 aaatgtaaaa tactatgctg acatagtaaa agaaaagtct gtacttagaa agcttataaa
    31861 agcttctaat gaaataataa atctaggata tagtggagca actaagattg aagatgtttt
    31921 agaacaagct gaaaagagta tatttgatat atcacaggag aaaactagtg acgattttaa
    31981 atctataaac ttagttttga tggatgccta tgatatgata gaaaaattat atactaacaa
    32041 gagcgatgtc actggtataa ctactggttt taaagattta aacaaaaaaa taaatggtct
    32101 acaaaggact gatttaatat taattgcagc tagaccagca atgggtaaaa ctgcattttc
    32161 tttaaacttg gttcaaaatg cagccttaaa aggtgatgct tctgtagctg tatttagttt
    32221 agagatgtct aaggaacaat tggtacaacg tatgttatct tcacagtcta gtgtagaatt
    32281 aaaaaaaata aagactggaa cacttaatga taatgattgg cctagaatta tagatgctat
    32341 ggcagtgtta tcagatgcca aaatacacat agatgatact cctggtataa aaatatcaga
    32401 actaaggtca aagtgtagaa aattaaaaat agaaaaagga ctagacttag tgcttattga
    32461 ttatcttcaa cttatggaag gtgaaggtaa taatgaaagt agacaacaag agatatctaa
    32521 gatatcaaga tcactaaaaa tattagccaa agaattaaac tgtcctgtag tagcactatc
    32581 ccagttatca cgtgcaccag aacaaagagc agaccataga cctatgttat ctgatttaag
    32641 agagtctgga gcaatagaac aggatgcaga tatagttatg ttcttatata gagacgaata
    32701 ttatcatgct gattctgaga gtaagaatat aggagaagta ataatagcaa aaaatagaca
    32761 tggtgaaact ggttctgtgg aacttgtttg gcttggtgaa gttcaaaggt ttggggataa
    32821 gttgagagac ctataatata acgaatatcc acagaacgtc ctttctttct acaggaaaaa
    32881 tgtggataca tgtcactaaa tatgtctaaa cattgaaatt tagctaaaaa attatccaca
    32941 gtatccacag atagcctgtt gataagtgtg aataagtaga taaagcaagc ttttggcttg
    33001 ctttatctgt gtataaatat taattattag gaggaataat atggaaaaaa taagcttaaa
    33061 atatatatat cccaatataa ttaaagtact tgatgaaata aacttattta gagtaattga
    33121 taataattta agagaatcta ttgttgttta tgctaataat gtggataatc agtatcatat
    33181 aaacatgact aatacaaact ttggaaacat aattaacata tgtaaattag aaaaactttt
    33241 agatgtggat aagtttatgg aaaaagttat aaaatcagaa aaagaaataa tagagaaaga
    33301 agagttttca aaaatagaag aatatatgtt aaatattgga gaatactaaa aaagttgaaa
    33361 aaaatacgaa tgtttgatag aataagtaag tagagtgttc gagagtatat aaaatataga
    33421 ggtgaattac atgaaaacag ttgcaattgt tggttctcaa tggggagatg aaggtaaagg
    33481 taaagttata gattatcttg ctactcaagc agatgtagta gtaagaggac aaggtggaaa
    33541 taatgcagga catacattag ttgtggaagg taaaaaatac gcattacatc taattccatc
    33601 tggagtttta aatccaaata cagtgaatat aatcggaaat ggaatagtgt ttgaccctaa
    33661 aggattttta gaagaattgg aaatgtttaa aatggataat ataagtacag aaaatataaa
    33721 aataagtaat agagcacatg tcatattccc atatcataaa gaactagatg tattgtcaga
    33781 agaagccaga ggcgatttaa agataggtac aacaaaaaaa ggtattggac cttgttatat
    33841 ggataaaaca gagagatctg gtattagaat atgtgactta atggataaag ataaattcgc
    33901 tataaaatta aaagctcaaa tagatgctaa aaatgaaata gttaaaaata tatatggaaa
    33961 agaagaatta tttgattttg aaactatata taatgaatat ttaggatacg cggaacaaat
    34021 aagaaaatat gtggcagata catcagttat tgtatatgat gcaataagag caggtaaaaa
    34081 agtattgttt gaaggagcgc aagggacttt attagattta gatttaggaa cttatccatt
    34141 tgttacatct tctcatccaa catctggtgg atttgcaatt ggtgcaggta taggaccaaa
    34201 tatgataaaa gatgttgttg gtatagtaaa agcatatact acaagagttg gagaaggacc
    34261 atttgttaca gagcaaataa atgaaactgg agataaaata agagaacaag gtcatgaatt
    34321 tggggtaact actggtagac caagaagatg tggatggttt gatgcagtta tagttaagta
    34381 tgcagctaga gttaatggat tgactagtat ttcatttatg ctacttgatg tattaactgg
    34441 atttgataag ataaaagtct gtacatctta caaaatggga gataagataa taacagattt
    34501 cccagcttca ttagatgatt tagcaaaatg tgaacctgta tatgaagaat tagatggatg
    34561 gaatgaagat ataactcaaa tagataactt tgatgacctt ccagaaaatg caaagaaata
    34621 tgtagccaaa atagaagaac tagttggagt aagtgtagat atggtttctg ttggtccaaa
    34681 tagagctcaa accataataa gaagaaatat atttgcttaa tattttatca attagataat
    34741 ttaaattgta aatagttgaa gaagagcatc ttaagataat gtttataatt attagagatg
    34801 ctcttttatg ttcgacttaa atttattttt tattaagtta aaattactga cacacattct
    34861 aactgaaatt aaagttgaat ttgtgtagag atgtataggt ttttaaaaag aattttgttg
    34921 aaaataaata gctaaagatg attttaatta tatgctaaaa aaaataaaaa aaactattga
    34981 ctaaaaattg tatagaagct ataatataac ttgtgagtga aagaaacgac gaaaaaagtc
    35041 gaaaaaatgt ggtctattag ctcagtcggt agagcacctg acttttaatc agggtgtccc
    35101 gcgttcgagt cgcggataga tcaccaaaat atggctcgtt ggtcaagagg ttaagacacc
    35161 gccctttcac ggcggtaaca ggggttcaat tcccctacga gtcaccagta tgggactata
    35221 gctcagctgg gagagcacct gccttacaag cagggggtca caggttcgag ccctgttagt
    35281 cccaccatat ttttaattag agataaaaac tagattatat gctggtgtgg ctcaacggta
    35341 gagcagctga cttgtaatca gcaggttgta ggttcgattc ctatcaccag ctccacaaag
    35401 tacataaatt taaattaata taattttcta tgttacagga tacttttaag tatctttttt
    35461 taatttcatt ttttattgta ttaaaaatga aatttacata taacaaaata ttgaattact
    35521 tgtaatgtga tagttttgaa tctaaaattt agaaacattc tagaatagta ttatgtaatt
    35581 agcaaattta atttatagta ccaataaata tagattgcta agaatataaa tgatttgtta
    35641 ggttaagata cattagatat gtaaatagaa aaataaaaag tatggtttaa tttatgtggt
    35701 ataagtttta aacagagaag caagtttgct cttacctctc tatttaaaaa taaaaaaatg
    35761 ttttttaagg gctattttat ttgaatcttt cccatctcaa atcatctcca gtaaattcta
    35821 aaatcctaaa cttatccaag attctagaga gagttctttg agtataagta tttcctatct
    35881 gagatggtgt taagttggtt gaaataatga tttttttacc agcaacaagt cttgtattta
    35941 caatattaaa gatttctcca ctagtaaaag aattattaag ttcagtacca aggtcatcta
    36001 ttattaataa atcgcaatca aacaagtttt tataattatc ttcacttatc tgattatttg
    36061 agtctctcct aaatttataa tcttcaagaa tatctaagat tctaaaagaa gtttgataga
    36121 ttacaacatt gcctttatct aacaattcct ttgcaataca attgcacata tatgtttttc
    36181 ctagtccagt agaaccataa aacagtaaat tttcactatt atctttctta aaatcatgaa
    36241 caaaattttc gcagatactt aaattgttta gcatattttc tctaggagat atttccccat
    36301 cagaactttt cttaggagaa aatatattca agttaaaatt cgaaaaattt tcctgactta
    36361 aaatcctatc taaattagac attttataag cttcatttac aatttcttgt ttaaggcaag
    36421 aacatttttc accattaggt aaaaatcctt tatctttaca agaaacacat tgaaacttta
    36481 tttccaaata atcaagaggt atgttatttt cagttaaaag tttttctttt tttaatttta
    36541 aagactctat attctcttta gtcttcttta caatttcatc tttagattta ggatttaaaa
    36601 gtactatttt agctaatctg agacctattt tagaaatttc atcatctaaa gattttattt
    36661 cagggattct attatatacc tcattttttc tatgttctaa taagagttca ttatcatctc
    36721 ttctcttagc atatttagca agtatttttc ttattttatc ctcattcatt taatcaccta
    36781 cttaaacttt tctttttgac tttttttaat aatctcatcg agctcatcag atgtatattg
    36841 agtgaatgtt tcgttgaaat tatgaaactt agttttcttg taagtattgt tgttttgagt
    36901 agtattaatc tgcttcttat taatattctc cttaactata cgttcttcct ctttttgctt
    36961 taaatcattt aaatttttta tatttttttc attccaattt ttaattatac catttatata
    37021 agatatactt gggtttgaaa tgttcttaga cttggaacat gcttttatta tcaaatctat
    37081 atccatatta aatttatcaa accaagtgtc cataagttct ttttctgact ttgatggttg
    37141 tcttgaaaat cccaattcat tgaaaatcgt tttatataaa atatatcttt cacttcttac
    37201 caaaaagctt tcttcaacat cttttggtgt atataaattt gaatcatacc aatttctaat
    37261 aataccttca atatatttaa ctggctttga tgtaccagtt ttatctttga cgtattcata
    37321 tgcgcaaagt atcatatcag ggctcatatt gtatttattc attatatcca taatactcat
    37381 cttttcactt gggtcgagat atcgcccaac tattttattt atagagttaa acatttttct
    37441 aatgcttgga ttttcagaag tagatacaac cttatctgta ttagatttta cagatgaatt
    37501 attgcttaat atattctcaa tatagaaatt ttttaaatct aaaaattcta ttgaataatt
    37561 aaaattatca tattctccat tgtcatgtat ttttataatc ttcttttcct cccagaattt
    37621 ccaagcagat aacacatcag acaatggtat atttaggttt ttggctattg aactattatc
    37681 gaacttagga ttagaagtaa tgtcgcatgc ctgtctatat cctaaaagat aaacttttac
    37741 gtataagccg tccgccattg gcataaatat atctataaag atattgggaa tagtgatttc
    37801 acctaaatct atttcattgc tttctttaaa aaacatttta tcacctcaga ttaaattata
    37861 tcatttttta tattatattt gtctgtaaac aaataaaagg tcacaagatt agcatgtaaa
    37921 tattttctaa aagtattcat tttgaaaagg aggagatatt ttggttataa aattcaacca
    37981 aaaagtaaga agaacattat cagtagcgat tctatttatg gtattaataa taggttgctt
    38041 tatagaaaag gatgacagtt tagaaacata caaagaaaaa actaattcaa aaataaatca
    38101 atataatatg gatgttatat ttgatgatga gactaagagg ttaatgtgca atcagaatat
    38161 tgagtacata aataatacaa aatcaaacat agataaaata tatttacata tatatccaaa
    38221 tgctttttcc aaaaaagatt ttgctccttt tgaaaaaagt gaaatgacaa gggcctatcc
    38281 taatggattt aacgaaggat atatagatat aaagaatata ttaaataaca atagtaaaat
    38341 ggagtataaa attaaagggg acaaaaatga catattagaa atagaattgg ggaaagagtt
    38401 aaaaccaaat gaaagaatgt cattagacat aaaatataac gtaaaaatac caaactcggt
    38461 tggaagattt ggatatggag aaaatactat aaatgttact aattggtttc ctatagtttg
    38521 tgtaaatgat gaaaggggat ggaatttaaa gagttatgaa actattggtg acccatttta
    38581 tagtgaaact agcgattttc atgtgaaact attgattcca aataaatata aaattgctca
    38641 tacaggaaaa cttgttaatg ataaacatga taataagaaa atgctatatg aaatagaagc
    38701 taaaaacgtt agagattttg catttatatt aagtagtaaa tttgatgtga ataaagtaga
    38761 ttcaaagggc gtagctatca atacatataa tttaaataaa aagctttcta aaaaagcaac
    38821 tgaagttgca aaagattcaa taaatatatt tagtgaatta tttgggaagt atccttacaa
    38881 agaattttct gttgtagcaa gtgacttttt tataggggga atggaatatc ctatgcttgt
    38941 tatgatagac caaagtttat ataatgaaaa aaatgaattt ttactagaat atgttattgc
    39001 tcatgagaca gcacatcaat ggtggtattc tgccgttgga aatgatgaaa taagtgaacc
    39061 ttggttagat gaagcactta ctgaatattc cacaatagtt tattttgaac aaaagtatgg
    39121 taaagatatg gcaaataagc ttataaaaac tatggagata cagacaaaaa gttatttgag
    39181 cgaaaatata tttaggccag cgaatgaata taaaaattct actgaataca gtttaaatgt
    39241 ttatacaaaa ggcgcaatag cgtttaatga aataagaaaa gaagttggag ataaagtatt
    39301 ctttgagact ttaaatgaat actataataa atataaacat aaaaatgcta atggaagagc
    39361 ttttgtggaa ctatggaata gtaaaggggt agatataaat aagattataa gtgaatgtaa
    39421 gtaaatttct tatagagtat taaattttat ttaatactct atttttttgg tataatataa
    39481 tttataaggc agaaaaagag gtgaaggaat gctaaagtat tgttcagtag ggagtggtag
    39541 tagtgggaat tgccactata taggatataa aaatactaat atactagtag atgcaggatt
    39601 aagtggcaag agaataacta caggtctcaa agacattggt atagatgcag ataaattaaa
    39661 aggaatattt ataacacatg agcatgttga tcatataaaa ggagcaggta tactatcaag
    39721 aaagtttgat ataccagtat ttgctaatat aaagacatgg tgttctatga aggacaaatt
    39781 aggtgatatc aaagataaaa atatgaaagt atttgaaaat gataaaacct attcattagg
    39841 tgatatcata gtgagacctt tttcaataga acatgatgcg tctgacccag ttggatataa
    39901 tttttataca gagaatgatg aaaaaatgtc tatagctact gatataggat gcataactca
    39961 aaatataaaa aaacatctat ataaatctaa gttagtagta ttggaatcaa attatgaccc
    40021 taacatgctt atgatgggtt catatacata tgctttgaag aaaagagtaa tgtcaaatgc
    40081 tggtcattta tcaaatgaag atgcagctaa tttctgtgtt gaacttatta atgaaggcac
    40141 agaatctata ttattagcac acttaagtaa agaaaataat tttcctgagt tagcatatga
    40201 gacctcaaaa ggagtattag catcaaatga tatagtagtt ggacaagatg taaaactaga
    40261 tgtactatca cgaaatgatg tttctaatgt ttatgagatg aagtagaggt gaataacttt
    40321 gctaaagaga aatttcgaaa acgttgaaga taataaaatt ttatactcta taaagcaggg
    40381 aatgatttta gcaatacctg ctattatgac tggttcaact gctcttgtaa ttttgaatct
    40441 tccaataaag gtttatcaag aatatttatc aagcttgttt aatggagagg ttacaaatat
    40501 tcttaacttt ataaatgatt ctactttagg aattatttca ttaataatat tattaacaat
    40561 aagctatagt tatgggaaaa tatatgggag caagtataca gtacttgttc ctatagttgc
    40621 aatgtgctct tttttagtat tttcacatgg taatgagctt gattcctata tagaaatatt
    40681 taagacaaag tggttattta catctataat tgtttctatg acatcttctg tattatttgt
    40741 aagacttaca gaatcttttg ttacaagtgt aaaatttcat acagaagggg ctgatgcaga
    40801 ctttaatatg gtagtttcag ctatagttcc tttcataata gtagtatttt tattctctat
    40861 ttttagagta ataatgataa gtctaattgg cagttcaaac tttcaagata tattttataa
    40921 tttattttca aatgtgttta atagaatggg aacaaatctt atgagtgctc tgttgtttat
    40981 ttttttaatg cactttatgt ggttttttgg gattcatgga ggtaatgtat tagatactgt
    41041 tgcaaaaaat ttatttgaaa atagcatggc aattaacata aatttagtta ataataatca
    41101 gttaccaaca gaaattttta ctaaaacttt ttttgataca atggttttat tggggggatg
    41161 tggcttttta ctatgtctag taattgcaat ttttcttagt gagaagcgta taaatgtaag
    41221 aaagttagct aaaattgctt ctataccagc tgtttttaat ataaatgaga tgctagtttt
    41281 tggaatacca attgttttta attatattat gtttgtacct tttgtaatta ctcctataat
    41341 tttaaccatt acaagttatg tggctatgtc tacaggcatt gtaccctgta cagtttcagc
    41401 tgtagaatgg acatcaccga tatttttaag tggatatata tctacaggtt caataagggg
    41461 tagtttgttg caattattta atctatgtgt tggtgttatg atttatattc catttataaa
    41521 gatatcgcaa aatagatata catatatgtt taaaaataat atagaaaatt taacaaagct
    41581 agtaaaaagg tatgaattaa caggggaaca gcctaatttt ctaaaccata atggtaaaat
    41641 aggctcaatt tcaaaaatgt tggcatcaga cttgaagttt gctatgaaaa gaggagaaat
    41701 agagattttt tatcaaccac aagtcaatta taatggagat gttgtagggg cagagggatt
    41761 acttagatgg aaacattcga taggagggtt catttatcca ccactagtta taattttggc
    41821 taaagaagaa ggttttctag atgaattagg agagtatatc ataaataaag catgtgttga
    41881 tttaaagaaa agtgaaaagt tattgagaaa ttctgttaag ttttccgtaa atatatctcc
    41941 agaccaactt gatgaaccta agttaccaga acaaataaaa aatatcatta gtagtaatga
    42001 tataaatcct aatatgctag gtatagaaat tacagagcag gttgcattat caggttcaca
    42061 aataattatt gaacgtatca atgcgataca taacttggga ataaagctaa ttatggatga
    42121 ttttgggatg ggacatagtt ctcttatata tcttcaaaat aataattttg atatagttaa
    42181 attggatggt tcattagtta aagagatact tacaaataaa agaagtagtg aaattataat
    42241 gactattgta aatctttcaa aaaatttaga ttttgatata gttgttgagt atgttgaaaa
    42301 tatggaccaa agagataagt tatataggct aggatgtgaa atatatcaag gatattatta
    42361 tagtaaagct ataccttttg aagagtttat agagtatgca aatcaagaaa gagagatata
    42421 attttataag agcttgtaaa ttctagtaag gtatagattt gtaataaaat taagtttagg
    42481 agaaatatat gaatataagt atagtagtag taggtaaaat taaagaaaaa tatttaaaat
    42541 taggtattga tgagtttaaa aaaagacttt ctaagtattg taagttagaa attatagagt
    42601 tggatgatga aaaagctcca gagaatttga gttctaagga aatggaaatt ataaaagata
    42661 aagaaggaaa gaaaatttta gggaaagtaa agcataatag ctatgttata gccttggcta
    42721 ttgatggaaa gagcttgtcc tctgaagaac ttgctaagac catgagtgat ttagcagtta
    42781 gaggtaatag tagtctatgt tttataatag gaggttctct agggctttct gatgaggtct
    42841 taggaagagc tgattatagg ttatcttttt ctaggatgac ttttcctcat cagatgatga
    42901 gattgatatt gctagaacag atttataggg cttataggat aaataatgga gaaccgtatc
    42961 ataaataaat gatacggttt ttgttagttt gccacttaat aatattaaaa taacaaaaaa
    43021 gtattgaaag tatattgtat ttaaggtaga attaaataaa atattataac attataatgt
    43081 ttagagggtt gttaataaaa atttggagga aaatatatga taaaaataat gttgtcctgt
    43141 tcagcaggaa tgtctacaag tttattagtt actaaaatgg aaattgcagc taaagaaaac
    43201 ggtatagagt cgcaaatttg ggcaatacca gaatcaacta tacaaaatga aatagaaaaa
    43261 tgtgacgtat tattactagg accacaagtt agatacgtat tacctaaggc tcaggaaatt
    43321 gctaagccat ataatatacc agtagaagtt ataaatatga tgcactatgg aacagtcaat
    43381 ggagaagctg ttttaaatag agctatagaa cttaacaaca ctaagtaata taaaatataa
    43441 tgtattttta atatatcaat tgggagaatc aaagaatgga tgaaaagatt atagaaatat
    43501 cttttaatat aataggttat gcaggtaaag gtaaaggatt agcctttgag gcaataaaag
    43561 aagccaagaa tggaaatata gaaaaagcaa aagatttatt aaaagagtct aaggaagtta
    43621 taaataaggc acataaatat caaacagaat taatacaaaa cgaagctagt ggaaacaaga
    43681 ctgaaataag tgttatactt atacatgcac aggaccactt aatgaatggt atgaattttc
    43741 aacagttggc tgaggaaatt gttgatttac atttaaagct acaagataaa taaaaattaa
    43801 agaaaataaa ttaagagagt tcttaaaata tacattatgt gtagcacact aattgttaga
    43861 ttattgttta atatttggtg agcaatacat taagtttatt ttgaggactc tttttgtatt
    43921 tagtttaaag ttaatagata tttattatta ataatataag attatatgtt ataatattat
    43981 aacatataat ttaagaggtg aatcatgtta agaaatcaac cattatatat acaagtcgta
    44041 gatatattaa agcaaaaaat attaaataac gaatataaaa ttgatgaaaa tattccaaca
    44101 gaaagggaat tagagcaaga gtttggtgtt agtaaaatta ctattagaaa agctattgag
    44161 atattagaat cagaagggta tgtagagaaa aaaagtggaa aagggacaaa agtaataagt
    44221 aatagccttt ttaataagct atcaaaagcg gagtcttttt caagcatact tttatctaag
    44281 ggacataagt tatctaaaga gactatttca attgaaaaaa taataaacga tacaagttca
    44341 caagtattta gtatatttgg agaaaaatgt agcaagatta ctagaatgta ttacttggat
    44401 agtaagccat atatattttt tactcattat ataccttttg atgaaaatct aactgttgaa
    44461 agttttaata atgaaagttc tttatatatg tatttatata ggagaaatat aaatataact
    44521 agatttgaag atgaattttt tatagaagaa tcagaactag aggtatcaaa ggctctaaat
    44581 ctagataaag acatattatt aggaagaaaa agaaagacct atgatgagag tgacaatata
    44641 gttgagttat catttgcaag atataataca gaagtacaaa attatgtaat taaatatgaa
    44701 atataataag aatcctgagt ttattaaaat gataatatac tcaggatttt tatttagttg
    44761 taaaaaataa tattataaca ttataatgtt tacaaacaaa cattataatg ttataatatt
    44821 tttaataaat aagtgatatt atcaattaca taaaaattag tttgtattat gaaatcgtta
    44881 ttgcattata aataaaggat aatatcaata atacaggggg ataactatgg aaaaattcgc
    44941 aagtttttta gagcgcaaga ttatgcctgt agcagcgaag ataagtaatc agagacatat
    45001 gagagctgta agagcaggta taatagcaac attaccacta acaatagtgg ggtcgttttt
    45061 cacaatatta ttaaacatac ctattgatgc ttatatggat tttatagctc catttaaagc
    45121 aaccttagac ataccattta gatatactgt aggattttta tctctatatg ctacttttgg
    45181 gatagcatca tcacttgcta aaagctatga tttagacacg acaggtgttg gtatgcttgc
    45241 agttatggca tttttagtct ctacaatagt tccaactcaa gtagttgaat cagtaggtgg
    45301 cgttatagaa gctggtagat ggatggatat ggcaaaactt aattcgccat cattatttgg
    45361 agctattgta acatcattaa ttacagttga aatatatcgt tttatgaagg aaaagaatat
    45421 tacaattaag atgccagcag gagttccagt agaggtttca aattcattta ctgcattatt
    45481 accaacagca gtaatcttaa tgttattctg ggtaataaga catattctag ggtttgatat
    45541 aagtgctgca ctaagtgcta tgttatcacc tttaaaagga ttcttatcag gaaatagttt
    45601 aggtggtggg ttactgacag tattcctaat aactttattt tgggtacttg gaatacatgg
    45661 tccagctata atgggaccag taataagacc tatatgggat atgtctatag cagaaaatat
    45721 aactgcattt acagaaggag tatcatctca tgcaatgcca aacatattta cagaacaatt
    45781 tttacagtgg tatgtatgga taggtggagc aggagctact cttgcattag ttgtaatgtt
    45841 tatgttttct aagtcgcaat atctaaagag tttaggtaga ttagggtttt taccagggtt
    45901 attcaacata aacgaaccta taatatttgg agcgccaata gttatgaatc caatactagg
    45961 gattccattt ataattggac ctataataat gacaattcta tcatatgttc ttactattac
    46021 agggattata cctatgatgg tagcaagatt accgtttgca atgccagcac cgatagcagc
    46081 agtaatgagt actaactgga gtatactagc aggtatctta gtattaatca actttgtgat
    46141 atcatttgct gtttattatc catttttcaa agtttttgaa aagcaacaat tacaaagaga
    46201 acaagaagaa atgagcgaaa atttataaaa atacatatac atagaagttt tttactatat
    46261 aaaatataga aaaaagctta taagttatta aaggtgaagg taggaggaat gaccttcgcc
    46321 tttaatttta tatattttaa ataatgtgat ttgaggagga gaaatatgga aagacgatta
    46381 gggatatcag tatatccaga gcatagtaaa atggaagatg ataaggcata tataaaaatg
    46441 gcttcaaaat acggattcaa aagaatattt atgtgtatgc tttcaattac aagacctaag
    46501 gaagaagtta aaaaacattt taaagagatt ataacctatg caagagagtt aggatttgaa
    46561 gtaatccttg atatagctcc aaacatattt gatatattag aaatatctta tgatgattta
    46621 acattcttta gtgagttaaa tgctagtgga ataagacttg actatggata tgatggaagt
    46681 aaagaagcta tgatttcttt caatccatac gatttaaaag tggaactaaa tatgagtaat
    46741 gatgtagcat acttggataa tataattact tacaagccaa atgtaaacaa tatatatggc
    46801 tgtcacaatt tttatcctca aagaggtaca ggcttgccat atgatttttt tgtaagatgt
    46861 tcaaatagat ttaaaaagta tggaataaga actgctgctt ttgttaattc aaaatatgca
    46921 acaatcggac cttggaatat aaatgatgga ttgtgtacgc ttgaaatgca tagaaactta
    46981 gatattgcta catcaactaa acacttattt gcaacaggat tgattgatga tgtaattgta
    47041 ggaaatgcat atgcaagtga agatgaatta aaaagaatgt ctgaagtaga tagataccaa
    47101 gttgtattta atgtagtagc taaggaaaaa acttctgaaa tagaaaaaac aataatggta
    47161 aatgagcaac actttagaag aggggatata actaatcagg tagcaaggtc tacagaagta
    47221 agaaaaaaat atgctaaaga aaatttccct aagcatgata atactaacat ctttaaaaga
    47281 ggagatgtag taattggtaa tgatgacttt ggaaagtata aaggggaatt acagttaata
    47341 cttcaagatt gtacagatga aagaaaaaat aaggtaggta gaataaaaga agacgaaata
    47401 atacttttag actttattga accttggagt aaatttaaga ttattttaga gggagagtaa
    47461 agtgaagata gacatattaa taaaaggtgg aaaaacagta gataaaagta taatagatat
    47521 agctatatta gacgataaaa taatagaagt aaaaaatcag atagatgatt ctaagtatca
    47581 ggcaaaccaa attataaatc tggatggaga gaaatttatt agtgcgggtt ggatagatat
    47641 acatacgcac tgctacgaaa gactagacct ttataaggat tatccagatg aggttggaat
    47701 aaaaagtgga gttactactg tagtagatgc aggaacaaca ggagctttag atataggtaa
    47761 attttatgaa gatactaaaa agtataaaac taatgtatat gctttaataa atattgctaa
    47821 gcagggaata acatctcaag atgaactttc aaatatgatg aatattgatg aagatgaact
    47881 taaaaatgcg gttaaaaaat acaaagattt tgttgttgga atcaaagcta gaatgagtaa
    47941 aagtgtcgta atttcaaacg atattaaacc tttaaaagta gctaaaagaa taaaaaacga
    48001 acttaactta cccatgatgg ttcactttgg gagttctcct ccaatgatag aggatatatt
    48061 cgactatatg gaaaaaggag atatattaac tcatatatat aatggaaagc caaatggaat
    48121 acttagaggc aatgaggtta aaaaggaaat tatagaagct agagaaagag gtataatcct
    48181 tgatgtaggt catggaactg aaagttttag tatggatgtt gcaatgaaat ctaaggatgc
    48241 agagattttt ccagatacta taagtacaga tatatatatt aaaaacagaa taaatggtcc
    48301 agtatataat ctatctacaa caatggaaaa gtttatctat atgggttact cacttgaaga
    48361 tataataaat aaagttacta agaatgcagc aaaagcaata agtttaaaaa ataaaggttt
    48421 aataaaagaa ggatatgatg ctgatttaac tatatttgat gtggttgatg aagaaaaaga
    48481 acttcaagat tctttgaata agtcagtaat tacaagtata tctataaaac caagagcagt
    48541 agtagtcaat ggagaatatt taaatatagg taagtctata cgagagaatg agtagaaggg
    48601 agaaactatt gtatgagtag catatttgaa aaatactctg taagacgtgt tataaatgct
    48661 tcaggtaaga tgactatact aggagtatca acagtagata aagaagttat tgaagcaata
    48721 ggtgaagggt gtaaaaattt ctttataata gaagaacttg taaataaaac aggtgaatat
    48781 atagcaaatt tattagggtg tgaaagtgca ctaatagttt ctagtgcatc tgctgggatt
    48841 gcacagagtg tgggggcaat gatagcaaaa gatgatatga gtctagttta taatgtaaat
    48901 aatcctaaga agcaagttaa aagagaaata ataattccaa aggggcacaa tgttgattat
    48961 ggagttccag tagaagtaat gataagactt ggaggaggag aagttgttga ggctggttat
    49021 gctaatatgt gtaacaagga acatataata agagagataa atgaaaatac agcagcaatt
    49081 atgtacatta aatctcatca ttgtgttcaa aagagtatgt taagtgtgtt agatgcagta
    49141 caagttgcta aagaatataa tttacctttg atagtagatg cagcggcaga agaagattta
    49201 aatgtatact atgaattagg agcagattta gtgatataca gtggtgctaa ggctatagag
    49261 ggtcctagct cagggttagt aataggtaag aaaaaataca tagataatgt aaagcttcaa
    49321 tcaaagggta taggaagagc tatgaaaata ggaaaagaaa atattgtagg tctaacatgt
    49381 gcaattgaga gatatataag taatgataaa gtaactttaa aagaaatgga ggacaagcta
    49441 aatccattta tagataagat aaatactcta aagggagtga gtgctagtat aactagagat
    49501 tcagcaggta gagagatact tcgtggagaa attgacttta atgaagatat aataaataag
    49561 tctacacaac aaattataaa tgaacttaga ggtggagaga tagccatata cactagggac
    49621 tataaggcta atgaaggtaa gattgagatt gatataagga gtgtaactgg aggtgattta
    49681 gatataattt ataataaaat aaaagagata atagagaagt agagagtgga ataagtgaca
    49741 ttataatgat ttaataaatt gaattttacc aatggagggg ataaatatga attgtacacc
    49801 acaatattat aaaaatagag tttgtttgaa tgttcttgca ggaagtataa aaaatgctaa
    49861 agaagtatat gatgcttgtg atgggcatat actagtagga ttattatcca agaattatag
    49921 cactgtagaa gtagctattg aagatataaa aaaatactca aaggaaatag ataatgcaat
    49981 atctgtgggc cttggagctg gagacccaaa tcagtcaaat atggtatctc agatttctaa
    50041 agaacttcag ccacaacata taaatcaagt gtttacaggt gtagctacat ctagagcatt
    50101 gcttggtcaa gatgatagta taataaatgg attagtttct ccaactggta aaccaggatt
    50161 tgtaaaaata tctacaggtc cattaagttc aaaagaaaaa gatggtatag ttcatataga
    50221 aacagccata gccatgatga aagatatggg aggaagctca attaaatttt tcccaatggg
    50281 agggcttaaa acaaaggatg aatatataga agttgcaaaa gcttgtgcaa agcataattt
    50341 ttatctagaa ccaacaggag gtatagactt agataacttt aaagagatag ttcaaattgc
    50401 acttgatgct ggtgtagaaa aagttatacc tcatgtttat acatcaataa ttgataaaga
    50461 aacaggtgat acaaaagtgg aagatataga agtactttat aaaataatga aagaattatt
    50521 gggataaatt tatgaatata ttagcttttg gtgaaataat gatgagactt tcagtacctg
    50581 gttataagtt tttaacacaa accaatgaac taaattatat aattacaggt acagggttaa
    50641 atatattatc tgggcttaaa aactttggat acaataccta catgttgaca aagttgccta
    50701 ataataatgt aggtaaagca tcaagtgcaa atgtaagaaa gcttggagta aaagatgact
    50761 ttatcacata tggaggaaat catataggag tttactttct tgaaagtgga tatggagaaa
    50821 gaccctcaga agtgacttat ttaaacaggt taaatagttc attctgcgag agtaaattac
    50881 aagattatga tattgataaa tgtctagaag gaatggatgt agtccatatt tgtggtattg
    50941 ctatgcaact tacagattca gttaaagaga ttgctttaga actagctaga aagtcttatg
    51001 aaaaggggat aaaagtattc tttgacttta attttagaca atctctaaat ccagaaaggt
    51061 cttatgatga tttagtaaat gattataaga aaatacttcc atattgtcat ggactgttcg
    51121 ctagttgcag agatataaat aaaatactta atatagataa tctagatata aaatctagtt
    51181 cagaattgat taaaaaagag tttgatatag atattgtagc tggaacgatg agaagatttg
    51241 atgatatgaa taatagattt ataaagggat atatatcaaa tgatgatggt tattttgaaa
    51301 gcaaggagta taagttagaa atatatgaca gagttggtgc tggggatgga tatgtcgcag
    51361 gaattatata ctcatatttg gaaaatatga gtaatgaaga tatagttgag tttggggttg
    51421 ctagttcagt gttagctcat acaacttatg gggataattc tttagtaagc acaagtcatg
    51481 tacttagatt gatgaacaat gaaaaaatag atatattgag ataacacctt tatatagaat
    51541 aaaattttta tttttttcag agtcaccttt gacttgctta tatttgttaa acatagttct
    51601 ttttagtgat tatgaatatt aaattaaaag ttaaataata aaatagtaga aaatagcatt
    51661 aaccatagaa aaaatggtta atgctatttt tatagtcaag attaattaat tttatattat
    51721 agaaatgaac ttttctaatg ctggatttgt atttttttta ttccatacaa ctacaacttc
    51781 aattctattt tctacttctt ttataggtac tattgcaata tcacgttcta tcattgtatc
    51841 tgtaacgcaa aatgaaggta aaatggatat acccatgtta gaagctacca atgattcaat
    51901 agtattaaga ttatttgaac gttgtaccac attaggtaca aaccccgctt cacgatatct
    51961 attctgtatc attgactttt gtccatactc atcccctgtt tcctttacaa aaataaattt
    52021 atcatgttgt aattcaatta aatcgataga atcctcattg taaagtggat gaccaggagg
    52081 taaaagagct accaaagaat atctttctac agttttatgt tcaaaatctt ttaatggttg
    52141 attttctgga ttaataacaa aagcaaggtc catagaatta ttttttacta agtttaaaag
    52201 ttcggttatc tcattagtac aaatatccat agatatatta gggtatgtat tagaaaattc
    52261 ttttaaatat tgttgaagtt tgtttttttc gtatcctatt aaggttccaa tgctcaaagt
    52321 tccaaaaaaa ccatgtgcaa attgttgtgt ttttgcaata gcatcattga tattttttat
    52381 tatagtgcgt gcctcagata aaaaaacttt tccagctggt gttagttcaa catggcgttt
    52441 acttcttgta aatagagtta catttatttg ttcttctaaa gattttattt gctgtgtaac
    52501 agcagtttgg gaaatataaa atttttctgc tgttttggta aaacttagat tttctgctac
    52561 agatataaaa tattctaatt gtttagtatt caaataatca cccctattta aacttgattg
    52621 tttgtaaacc ttatttatat ataattaaaa cttattatag tataagaaaa tttactttta
    52681 aagaatattg gaaaatattt gtataaaaat atatgtttta agtatttctt tgtgttagat
    52741 tttataaatt tattaataag aataacttat atattcccat gaaaacgata ttggatttaa
    52801 gtaagtttgt ctcataaaat gaaagtatat caattgataa tacttcaaat aagaagggag
    52861 aaaaaatgga agataaattt tatgcaaaag gcaaaggaaa taatggatat attaaaaatc
    52921 ttgaagtttg ttccttcaat aacttggatg gaacttgtgg aatgtttcaa atggctctgt
    52981 acaaaagaga tgaaaaatac tatttatatg gatgctgttt tggaggaaat aaaaaaaatg
    53041 gagtaatgat tagtgatatt acagaccctt ataatccaca atttataaaa cattttcaaa
    53101 tgttagaccc taaagagtat cctacaacaa caactccaaa aattcaaata gcagatgatt
    53161 taatgatagt agcaatgagt tgtggaagtg ggccaggagc acttgttgac caggctaaat
    53221 tagcaaatat taagtgtgaa gcaggaatta gaatatatag tttaaaagaa gaccctttaa
    53281 atcctaagtt tttaggatat tgggattgtg gtttaaagca tgtaatgggt gttcatagat
    53341 tcatgtacaa tggtggaaga tatgtacatt tatcaagtga ttgtgttggc tttgaaggcc
    53401 tggtttacag agtcatagat ataataaatc ctactaatcc agtggaaata ggtaaatggt
    53461 ggagaccaga ccaatatgca gatggatacc caaatagaac ttttgatgca ggagcacctc
    53521 attgcccaga atttatggat aaaggatggc ttcatggacc tccatttgta agagatggaa
    53581 aagcatattg tggttatgga ggagctggtt taattatatt agatgttgaa gatttaacaa
    53641 gaccaaaatg cttaggtgaa ttgccattta tgcctgcatt ttctagtaga cttgcaggtg
    53701 caagaactca tacagcatta ccattgccag gaagagattt agtcgttgtc caaaatgagg
    53761 gagaacgatt tcaattcttt aaaccagata atattacaga tgttcaagct atgaataata
    53821 tacatatggt tgatgttagt gacccaacaa aaccaacatt aattgctcaa tttccatatc
    53881 ctgaagtgcc aaaagatttc ccttatccta actttaatgt cgcaggacta ggaaaaccag
    53941 gaccatttgg tccacataat cttcacgaac caatggataa taagtcatgg ttagagcaaa
    54001 gaggagatag agtatattgc tgttatttcc atgcagggtt aagggtttat gatgtatcag
    54061 acccatatta tatcaaagag ctagcatatt ttataccacc aaatccaaat aaaacaccag
    54121 aagagtctta tttcccagga tttctaggac cacgcttggc agtaacagaa gatattattg
    54181 ttgatgatag aggctatatc atcatagatg ctttagatga tggattttat atattaaaaa
    54241 tgaaagaaga ttaaataagt actaaagagg gagagttgaa aatgaaaata ctaggtattt
    54301 cttttggaac aaaaaatgga aataatgaca caatgtgtaa agttgcactt aaaggtgcca
    54361 aagaagcagg ggctgaagta gaatttattc aaatgtcatc tattaacatt aaacattgta
    54421 ctggatgttg tgcgtgcgtt aagactttat tatctggaaa aggtagtata tgtgtattaa
    54481 aagatgattt tgaatggttg cttgacaaaa tgaaagatgc agatggtata gtagtttcag
    54541 accctatttt tgaagaaggg gcatcaggat tattccatac tataatggat cgttttggac
    54601 caagagcaga tagaggaaat aatgttatag ggacaaaagt tgcagaagct acaggaggaa
    54661 aaattccaga ttcaagaatg cttaatgata aagtaatatc atttatggga atagggggtt
    54721 ctgactgggg gacgagagtt cagtgtgaac atgctatgct agctctaata ccaatgtgga
    54781 aagttataga taacgcttgg ttcccatggg caaaggaatt agtaatggat gatacaaagc
    54841 ttgctcaagt tcgccaactt ggtttaaata tagttgaagc agcaaaagat tttgaaaaag
    54901 cttcatacca aggagaagaa ggtgtatgtc cacattgcca taatagatta ttctacattg
    54961 agccaggtac taaaaaggca atttgtgctc tatgtggtat agttggagaa ttagatacta
    55021 taagtggaaa aactatattt agttttccag aagagcaatt aggtcatgct catgacactt
    55081 taccaggtaa gtttatacat ggtgatgata ttaagaaaat ggaaggtcat tatgcagaag
    55141 ttcgtaaaac accagaattt aaagaaagaa aaacagctta taattttata gaaccattaa
    55201 ctaaagaaaa gcaagctgga gcttcattaa gataataatt aaaatactaa gactcttttt
    55261 taagggatgt tataggaggc ttattgtatg aatgaaaagc cgagctttaa acagattgaa
    55321 attattttag tagttatttg tttagtattt gcacattaca atgttagatt aactccagaa
    55381 tttattgcta taattatacc actatactta agttatttta tagtatctat tattgcaaac
    55441 caaatagcaa ttaagctatt agagataagg caaactaggg aagctactag ttacaatata
    55501 ggaaatggat agaaagaaaa aagaaatatt aacactgtcc atgggtattg ctttactacc
    55561 tcctttatgg gcagtattag caccttatat aggaataaaa actggagctg tagcactaat
    55621 ctgtgcagga ttatatgtaa ctaatggtaa taagcaaaaa gatggattaa aaataatgtt
    55681 tggtttttgg tgtggggatt tatgggcagt gttagccatt ttaattatgg aatatatgaa
    55741 cttcaatcaa aacctggaat tatttttaac acttagtata ttaggttttt ttgcagttgt
    55801 aattgcatcc tcatttgaaa aaataatttt cctaccatca tggctttgtg gttgggctat
    55861 aggtctaact attatgacag gtgaaaatat tattaattta caagatattt gtattcaaat
    55921 tgctatagct atggcagtag gaatttggta tgtgggtgta ggtgtagatt tgtttacaag
    55981 atatattttg agtaaggata agaaaaagtt aaattgaaag catgtgaata tactttggtt
    56041 ataggagaat ggttatgggt tttgaattta aaataatgag aagtttaata tatgtaggac
    56101 ttgccaagga agaatataga cctaagttaa tggactggtt atatcgtcac catattccag
    56161 atagtattag cacttttgga ccatattgta ctaaatatgc cttttatcaa gcatatccta
    56221 caccaaatga aggtgagcgt tttggtgcac gtaagatgca gctaacagaa cattattggc
    56281 ttgtagatga gcatatgcct gaaatggcaa atagaattat gacagaatat atgcctatgg
    56341 atgttctacg ttggcaagga tgtataccag atatagaaaa taaaagggtt catgaaaatg
    56401 cagaaagtgg agatgcagga cgtgcagtgg gtggagataa cggatgtcca ccatttatat
    56461 ttgcatttgt tccaataaac tgggaagaag attttagagg aaaaggacgt actgtacaag
    56521 atggaccaaa ctatcgttgg caatttatga ttaagtatcc agatggtgtt tccaaagaag
    56581 aaggagaaaa atggttctat gatgaggtag ttccatactt tacaaactgt tgctatgtta
    56641 atcgttttgt cagtagtaaa ataatgatta attatggagc aactgctttt gaccgtgtag
    56701 cagaactatg gtttgaaggg gaagaagagt ggtataaagc tgtggttgaa gaggcaaaat
    56761 cgtttattaa aaagccagaa tgggcacaag aagaggagtt cccatattta aaaccacaat
    56821 tcaatatcgc atcagtattt ttaggtgata tagcaactat ggatgcatac tcacagtatc
    56881 gtggatatat tccaatgaga taatatagtt tatggtaagt agaggaggta cttgctatta
    56941 ctagagaaaa agacttgttg tagctttaaa agtaggtgaa tatataattt taaaataaat
    57001 ttataaaaac taagattaat aaatatgaga caatagcatt agaataattt gatatatttg
    57061 ttaaaagaat atttagaatg tgtttaaata tgaagatgtt ccttttatga tgtcagatag
    57121 ttgaaacaat aaaactgtta tcatgaaggg aatattttta tgtctaggaa atcatttaaa
    57181 ataaaaatta aatgtgttta atgacatctt aaagtaaaag aaatattgtt agaaatatgt
    57241 agataatata gtatttataa tgtattatat taacaagttt acacttggat tataaaataa
    57301 aaagagtgat tctaaaggtt gtaaatacta tactgacttt gatacttcaa agtttagata
    57361 atgctgtagt tgttaataga aatacgttta atgagcataa ataatttatc taataagtag
    57421 gaaaatataa tgtatgtaat tggacaagta cctaaatttt taggaatgtt cagagacata
    57481 ctaaaatttt atgagggaaa agattagtta agaacaggag gaatagatat ggttttattg
    57541 attgttgata cacaaaaatt aataacaaat gaagagctat ataattttaa tgaatttgta
    57601 gtaaatttag taaaactaat tgatacagct agaaaaaaat atatagaagt aatatatgta
    57661 cgacatgatg atggaattga ttgtgaatta accaagggta aacatggttt tgaaatatat
    57721 gaagaattta agccatgtga tgaagaaaaa atatttgata aagatgtaaa cagtgctttt
    57781 aaggaaactg gtctattaga atacttaaca aataagaatg aaaaagatat aattattgct
    57841 ggacttcaaa cagattattg cattgacgct actataaaat gtgggtttga acatgggttt
    57901 aatataatag ttccatctta tgcaaataca actattgaca attcattcat gtcagcagaa
    57961 caatcataca aatattacaa tgaatttatc tggaatggaa gatatgcaga gtgtatttca
    58021 ttagatgaga cacttaaaag aatgaattag gtaagtatca ttttattata tgagataaac
    58081 tttaactttc ttagtttaaa atattaaagt taaaaggaac atttattatt agatatttta
    58141 tttatataaa ttaattgaag aaaaaaggaa ttaaactaca agttaaaaaa taaatttaat
    58201 acattagaat tataaataag gcacatcaat tttttttata ttaatgtgct ttttatttat
    58261 ag
//
LOCUS       DBGJFK010000014        58202 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.014, whole genome shotgun sequence.
ACCESSION   DBGJFK010000014 DBGJFK010000000
VERSION     DBGJFK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58202
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.014"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..430)
                     /locus_tag="ACOIAP_001125"
     CDS             complement(<1..430)
                     /locus_tag="ACOIAP_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HGZ2638029.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPVETNLLKSEVERLSEK"
     gene            complement(502..1884)
                     /locus_tag="ACOIAP_001126"
     CDS             complement(502..1884)
                     /locus_tag="ACOIAP_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate:H+ symporter"
                     /protein_id="HGZ2638030.1"
                     /translation="MITGYGLLVAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFRISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(2020..2928)
                     /gene="garR"
                     /locus_tag="ACOIAP_001127"
                     /pseudo
     CDS             complement(2020..2928)
                     /gene="garR"
                     /locus_tag="ACOIAP_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422806.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0046487 - glyoxylate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
     gene            3309..3980
                     /locus_tag="ACOIAP_001128"
     CDS             3309..3980
                     /locus_tag="ACOIAP_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2638031.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEIIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIIEIFQIRSAIEGFCTFLITSQYKEA
                     RAIETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYKTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            4082..4630
                     /locus_tag="ACOIAP_001129"
     CDS             4082..4630
                     /locus_tag="ACOIAP_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638032.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILKKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            4892..5200
                     /locus_tag="ACOIAP_001130"
     CDS             4892..5200
                     /locus_tag="ACOIAP_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638033.1"
                     /translation="MFNKVYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(5361..7151)
                     /locus_tag="ACOIAP_001131"
     CDS             complement(5361..7151)
                     /locus_tag="ACOIAP_001131"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638034.1"
                     /translation="MKKSKSFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGIPGASVNFDYVTKILVILACIYVANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQNRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADTESE"
     gene            complement(7151..8878)
                     /locus_tag="ACOIAP_001132"
     CDS             complement(7151..8878)
                     /locus_tag="ACOIAP_001132"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638035.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSVLLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKENENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(9123..9668)
                     /locus_tag="ACOIAP_001133"
     CDS             complement(9123..9668)
                     /locus_tag="ACOIAP_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGZ2638036.1"
                     /translation="MRKVILYIATSLDGYIAEEDGSVSFLDEISSVFKNEQEDDYNTF
                     YDTIDTIIMGNSTYVQIANELSPNEWYYKGKECYVYSNIINEITENVKYTNLEPKKLI
                     EQIGREKDKKDIWIVGGGDIVKLFMKDNLIDDYYIYILPIILGRGISLFKSGIDKTNL
                     NFKKASNIGELVKLEYSKKQK"
     gene            10002..11114
                     /locus_tag="ACOIAP_001134"
     CDS             10002..11114
                     /locus_tag="ACOIAP_001134"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGZ2638037.1"
                     /translation="MKISEVSTPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKLECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     AEAVSKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIERVIEVDIRENSKQIIL"
     gene            11468..12511
                     /locus_tag="ACOIAP_001135"
     CDS             11468..12511
                     /locus_tag="ACOIAP_001135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638038.1"
                     /translation="MDFLKEDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDK
                     LLEIHLDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITL
                     QNLDKNKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKND
                     MKIEIHTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNASQANGK
                     SAALNGNCTFIVNDTNDTIGPLYSNKNSNTIEDSSIANKVASFIPLSNTNVSKIMCMI
                     NDRNSNNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKID
                     FLSFLNKMQKLNS"
     gene            complement(12761..13594)
                     /locus_tag="ACOIAP_001136"
     CDS             complement(12761..13594)
                     /locus_tag="ACOIAP_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2638039.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENI
                     EDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGRKITWGIITIACLLIA
                     IIVFPKLPHQIPIQWNNGVANYVDKKFIYAYPAICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDIFVFIALLIIGVYKLFKKY
                     N"
     gene            complement(13921..14451)
                     /gene="bilS"
                     /locus_tag="ACOIAP_001137"
     CDS             complement(13921..14451)
                     /gene="bilS"
                     /locus_tag="ACOIAP_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein BilS"
                     /protein_id="HGZ2638040.1"
                     /translation="MKSLILYSSLTGNTKKIACSIYEAIQGKKEIKNISELVDDSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASTKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKVKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EANVFAKNMMIKASTM"
     gene            complement(14533..15627)
                     /gene="bilR"
                     /locus_tag="ACOIAP_001138"
     CDS             complement(14533..15627)
                     /gene="bilR"
                     /locus_tag="ACOIAP_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin reductase"
                     /protein_id="HGZ2638041.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFCDIAKS
                     GVALITLGDVSVRPSFHNMAMSLTDEDGVMKYKKIVDEIHNSGAKVSAQIFCSDYDVN
                     LIKDTMKMGITSHVEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLIGSFSSSIFNNRNDEYGGTCENRSRFASEIISSIRNEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLFSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPINNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMISMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTHSQFGCILD"
     gene            complement(15629..16075)
                     /gene="bilQ"
                     /locus_tag="ACOIAP_001139"
     CDS             complement(15629..16075)
                     /gene="bilQ"
                     /locus_tag="ACOIAP_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bilirubin utilization transcriptional regulator
                     BilQ"
                     /protein_id="HGZ2638042.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNRIKKEFSDEEYKELVKKLHVVKDIKTAMEEE"
     gene            16381..17571
                     /locus_tag="ACOIAP_001140"
     CDS             16381..17571
                     /locus_tag="ACOIAP_001140"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGZ2638043.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTKENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALENAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTNIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPSGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            17741..18703
                     /locus_tag="ACOIAP_001141"
     CDS             17741..18703
                     /locus_tag="ACOIAP_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGZ2638044.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALNLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILSKNKLNVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMIIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(18825..19487)
                     /gene="zmp1"
                     /locus_tag="ACOIAP_001142"
     CDS             complement(18825..19487)
                     /gene="zmp1"
                     /locus_tag="ACOIAP_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HGZ2638045.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHAESTTIQQNKDILSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNVLNQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(19587..19672)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(19857..22760)
                     /locus_tag="ACOIAP_001143"
     CDS             complement(19857..22760)
                     /locus_tag="ACOIAP_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HGZ2638046.1"
                     /translation="MRKGNKKALLISLIMILSMVMSTIYPTVSYALELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEEEKQTDNKKPEQMPEKEKPTDNKNPEQTPEKEKPTDN
                     KNPEQTPVGEKPIDSKNPEHTQEDKSTDNKKSEQSLEDEKTLDNKNPEKTPKEEKLLE
                     EENLLKVLEDELNEENEDYGFIVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSIT
                     FKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSIMQGKIGLEAYVKKVDED
                     TNAKIHIETTGKIENGSGDVDVEIKPGDKTEVPDAKGTLKKLVEGRKSTTVFMPVKNK
                     DINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNITQSKNSIS
                     VNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSVFDRGDNY
                     LLTKGHSGATNITQVGQVINYQISVNDDKSPISNVVITDNIPEGMRLTTSGEAGHDFR
                     VVEVPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFFI
                     AYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLSSSDNQ
                     IVKYKINMSTYGVYDAGQVNLLDEVNPALKISNIKYSDNLELKKEAGDGKNTIRLVNK
                     YEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNIAQINGSSPPGVETTKQGYAFEAKK
                     VDALDKNVLSGARFNLEDVSGNIVVKDLVSDEDGVIQSSVKKPGIYYLVEFRPPNGYE
                     KLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVPPNTDEPVVNPPVPPSTDKPKKPS
                     SPSDTDETVVINPPVPPSEDMTNPPIPEVVNPPIPPSEEVIETPVKQIVPIPEVVKPS
                     VSEEKNNKVKDDTLVNPPVPPKTGDNTTIIGEILLVLGAIVGLIVLKRNKNAN"
     regulatory      complement(22873..22958)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(23085..24263)
                     /locus_tag="ACOIAP_001144"
     CDS             complement(23085..24263)
                     /locus_tag="ACOIAP_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGZ2638047.1"
                     /translation="MFSKILVKTFIRDSENVQNRDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPVPIKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEDMVNSIIELLLSYKHIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPVCLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYDCVIVVDKDFI
                     "
     gene            complement(24954..27728)
                     /locus_tag="ACOIAP_001145"
     CDS             complement(24954..27728)
                     /locus_tag="ACOIAP_001145"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HGZ2638048.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAQALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITSKIEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAITSEGELNLIGSSRSYMKEDNLVFSGFVGIIDPLREGVK
                     ESIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFAQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRMMKN
                     SRTMNCNSKN"
     gene            complement(27899..29155)
                     /gene="glyA"
                     /locus_tag="ACOIAP_001146"
     CDS             complement(27899..29155)
                     /gene="glyA"
                     /locus_tag="ACOIAP_001146"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGZ2638049.1"
                     /translation="MLKTTKISDPELYKIVANELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSTVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECKPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIILCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLGT
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(29227..30729)
                     /locus_tag="ACOIAP_001147"
     CDS             complement(29227..30729)
                     /locus_tag="ACOIAP_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HGZ2638050.1"
                     /translation="MRALNVIERAGNKLPDPVTIFLLLCIIVVILSAIISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDSSYQGNPAMNLYFAFVSAIILTFAGAF
                     VTEKFIAPRFSKYSDAVNDKDMEELSELENKGIKYALLSLLAIVVIIVALCIGENAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGRVSNKIKNDKELVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKVLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEVIILLLFMSIGIPLGPGGGISYVL"
     gene            complement(30828..32012)
                     /locus_tag="ACOIAP_001148"
     CDS             complement(30828..32012)
                     /locus_tag="ACOIAP_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2638051.1"
                     /translation="MHELISISEKYKEDILDFFTDIHMHPELSFKEFRTTKVIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPICEEVDIEYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEK
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYTIACKSVCDLYSEDAIVDPVPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCMYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KK"
     gene            complement(32243..33331)
                     /locus_tag="ACOIAP_001149"
     CDS             complement(32243..33331)
                     /locus_tag="ACOIAP_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638052.1"
                     /translation="MSDKVNIKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     VGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIISGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNIAPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCREKSTQGQE"
     gene            complement(33615..34313)
                     /locus_tag="ACOIAP_001150"
     CDS             complement(33615..34313)
                     /locus_tag="ACOIAP_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGZ2638053.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     TGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFDYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIK
                     KGMTPKVYKLNTKN"
     gene            complement(34427..35932)
                     /locus_tag="ACOIAP_001151"
     CDS             complement(34427..35932)
                     /locus_tag="ACOIAP_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGZ2638054.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELVVSNIV
                     NNFETSEILEFNKNNKIENTPVNYSENTLNLYAAVESIRGQFIDPFKIPLIIYDDYWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSANQFTCKYGITIYNISIIYKNNSIGV
                     IRGGYILMSDSSLGVGHRNLYDIPEGAARTMKRLLNQIAKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMVSIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIENYLNLQKLRYGDALKVKYLIPKKLYNLSVP
                     FNFIQPIVENAFTHGSRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDKNNIDKIKAG
                     IRINNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPSENYKEYV"
     gene            complement(36205..37476)
                     /gene="serS"
                     /locus_tag="ACOIAP_001152"
     CDS             complement(36205..37476)
                     /gene="serS"
                     /locus_tag="ACOIAP_001152"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGZ2638055.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKAFNLDEVVKLDDERRKILQE
                     VEVMKNKLNTASKNIPNLIKEGKDVENEKIKLKDLSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPGVPQGETDDDNVEVRSWGETTKFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYAHTLNGSGLAIGRS
                     VAAILENYQQEDGSVIVPEVLRPYMGVSVIK"
     gene            complement(38263..39864)
                     /locus_tag="ACOIAP_001153"
     CDS             complement(38263..39864)
                     /locus_tag="ACOIAP_001153"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HGZ2638056.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKNVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETYDPEGGHIGRVEGSEEPNGYLEENAFFNVSSKIKPPSSNEIFNSIEKAQDIYLS
                     YGITTAQEGLMEENQFNLLKAMANQNKLKIDVVGYVNLKKSKPVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSKPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAAEQLIDVFEKVLTLKEQSSNNMRPVMIHAQTVREDQIDDMKRINMIPSYF
                     VAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAVN
                     RITKKGVQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPLT
                     IDPMKIKDIKVLQTIREGEVLYSLK"
     gene            40250..41176
                     /locus_tag="ACOIAP_001154"
     CDS             40250..41176
                     /locus_tag="ACOIAP_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HGZ2638057.1"
                     /translation="MNKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMKGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSIGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(41297..42295)
                     /locus_tag="ACOIAP_001155"
     CDS             complement(41297..42295)
                     /locus_tag="ACOIAP_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HGZ2638058.1"
                     /translation="MNKKFKSLYITEEEGNFKRNIVERDVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVRLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKDMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKQALLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGTHVGRTVVDLEKI"
     gene            42399..42836
                     /locus_tag="ACOIAP_001156"
     CDS             42399..42836
                     /locus_tag="ACOIAP_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGZ2638059.1"
                     /translation="MEDKYIVHFISKTKTNMIKFIENKLSKNDLDELIPTHGNILTAL
                     YENNGILTMKEIATKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            42922..43509
                     /gene="rbr"
                     /locus_tag="ACOIAP_001157"
     CDS             42922..43509
                     /gene="rbr"
                     /locus_tag="ACOIAP_001157"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HGZ2638060.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENINISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHVGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(43811..44431)
                     /locus_tag="ACOIAP_001158"
     CDS             complement(43811..44431)
                     /locus_tag="ACOIAP_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HGZ2638061.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSTITFEELKLIVNIIEENFTSIYNENGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(44439..45206)
                     /locus_tag="ACOIAP_001159"
     CDS             complement(44439..45206)
                     /locus_tag="ACOIAP_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HGZ2638062.1"
                     /translation="MEKGSIKILGEGFISSGEYESIRIVGSAKSKGNIKSDEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLSIYGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVSENMYAQDIKIYGEMRNKSNIECEDIKVYGVIECDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDVFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSIFLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(45247..46068)
                     /locus_tag="ACOIAP_001160"
     CDS             complement(45247..46068)
                     /locus_tag="ACOIAP_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638063.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNIAGTGKIEGSVKCSKFNSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGDINSVEIDTSGIINVEG
                     SIKSDIIRGEGYLKANENIDCENINLSGIMECNGFLNCEEVNISLNGISNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYIESKLFANIIEADEIS
                     LENSEVKVVRGKNVKIGKGCYVESLEYSEIIEIDEDSIVGEIKNINEKVKLKKDK"
     gene            complement(46357..48267)
                     /gene="phnW"
                     /locus_tag="ACOIAP_001161"
     CDS             complement(46357..48267)
                     /gene="phnW"
                     /locus_tag="ACOIAP_001161"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HGZ2638064.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPIEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVIETIEKLRENGLKIGSTTGYTREMMDIVQPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTE
                     EEVENMDKEELKIKMNTVSKKFKEAGAHFVIETMAELEDVLVKIENKTIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNDLVQDVRRRLISLGTKNTDKYTSVLMQ
                     GSGTFSVEATIGSTIPENGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDVEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKVYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEELSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKANGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIERFINR"
     gene            complement(48557..49342)
                     /locus_tag="ACOIAP_001162"
     CDS             complement(48557..49342)
                     /locus_tag="ACOIAP_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGZ2638065.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNSTNLDKKQSIAKYASKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASLYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(49557..49787)
                     /gene="dltC"
                     /locus_tag="ACOIAP_001163"
     CDS             complement(49557..49787)
                     /gene="dltC"
                     /locus_tag="ACOIAP_001163"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGZ2638066.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(49806..50954)
                     /gene="dltB"
                     /locus_tag="ACOIAP_001164"
     CDS             complement(49806..50954)
                     /gene="dltB"
                     /locus_tag="ACOIAP_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGZ2638067.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYVYWSFLFISMLPIIINKISP
                     VTSFGMIGFIGISYLNFRAIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSIIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKEKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(50954..52468)
                     /locus_tag="ACOIAP_001165"
     CDS             complement(50954..52468)
                     /locus_tag="ACOIAP_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HGZ2638068.1"
                     /translation="MKIIEGIKKYSNTDRIALICNGDKLSYKDLNEYSDAISIFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLKDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPKLESMIFIGEALSKNLT
                     KELMSRFPNTRVINGYGPTEATVGVSVNDMTQKAIEDEKSLPVGYPMSNCKIKILDEA
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGIKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNVVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(52589..53779)
                     /gene="dltD"
                     /locus_tag="ACOIAP_001166"
     CDS             complement(52589..53779)
                     /gene="dltD"
                     /locus_tag="ACOIAP_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGZ2638069.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTLLEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKSPINWSHERKKAIEDAKKRVGKNPLNIDNYYYK
                     QHFKDGIDQYKGRDKDVNLLTSKEFESYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQNIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(54069..55088)
                     /locus_tag="ACOIAP_001167"
     CDS             complement(54069..55088)
                     /locus_tag="ACOIAP_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGZ2638070.1"
                     /translation="MMGKVRFGIVGTSNIANIFLKAASKVKDFELVAIYSRNLEKARE
                     FGMSHGASIFFDDLEQMAKSKDIDAVYIASPNALHSRQAIICLKHKKHVLCEKSLASN
                     LKEVKLMIKTAKDNNVLLMEAMRITCVPNFRAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKSVKAVSHVLQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSYENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(55264..55803)
                     /locus_tag="ACOIAP_001168"
     CDS             complement(55264..55803)
                     /locus_tag="ACOIAP_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HGZ2638071.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKEGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFTLLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSIYWTILTFIGVRYFQVYIVDSLYSLIIPYWPILVIILLATLF
                     VDEVLTIKFLRGNKDIVER"
     gene            complement(55904..56584)
                     /locus_tag="ACOIAP_001169"
     CDS             complement(55904..56584)
                     /locus_tag="ACOIAP_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2638072.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWIETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTNIYDSSVPIIDLYDEKTKNMIEFMDREGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     SSKECHNL"
     gene            complement(56613..57902)
                     /locus_tag="ACOIAP_001170"
     CDS             complement(56613..57902)
                     /locus_tag="ACOIAP_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGZ2638073.1"
                     /translation="MRELLNVTLIIILVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIISIFNLSESIVYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLVVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRILVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT        19265 a         9786 c         6500 g        22651 t
ORIGIN      
        1 acttctctga taatctctct acttcgcttt ttaataaatt agtttcaaca ggataatgtc
       61 ctctcatagt agaatcacta cgacttatga ttataaaatc cttattaact ttctttgata
      121 catccacaat attctttgaa atttctttat gcgcttttgt agtttgagca acagtaaatc
      181 cccttgaatt agtaagtata aaaaacatac tatttttctc attaaaacct tgttccatac
      241 tatccttatc ccaatcagta taaacagaaa tatcatgaac tgtttgtaca cctgttgggt
      301 catcatctaa tacaacaatt tttctatcta aatgcttaag ctcatctgca agaagtttat
      361 ttaatctgtc ctcatctact tgtttaaaag tattaagtat atctatgcta attggtttta
      421 cttctctcat ttaaaacgcc cctttatgta atttgtatag tctaaatgta attttatata
      481 atataaacaa tagtttgtta tttatagacc tggaagtggt ataattccat ttataacact
      541 aagcaataaa accattataa atgctacaac tccagcaatg gttcctccaa ttgtccaaga
      601 gtttaaagta tctttaactg ataatccact aaatcttgaa agtacccaga atccagaatc
      661 atttggaagg gagaaaccaa ctcctccagc acatatagca agccctacta aaactggtga
      721 cattccagtt gccaaaattg taggtcctaa aattgatgat gttgttacta aggctacagt
      781 agcagaacct tgagaaattc taagcaaggc acttaataaa aatccaagca ctacaactga
      841 tatactaaga ccagacatag tatcaactaa gaagttacct ataccacttg catttataac
      901 actgccaaac gcaccacctg aacctgttat caataatatt agccctgctg aatcagcagc
      961 ttcaataact acatctccca taggtttatt tatgtatttc tttaaaaatc ctattgccac
     1021 caatattcca agaagtattg ctatgttttt atctcctata aatgcaagca ctccactcat
     1081 tgtagaacct ttttctaaga acatactaaa tacatttgat ataagtataa gaagtattgg
     1141 gaacaataaa gaaaacatag aaattctaaa acctggtact ttagaagaat catcatcttc
     1201 aatttttatg ctatcttttc cctgttctaa atttttttct ctatcattct catcaatagc
     1261 ataagctgga tatttttcaa aacgttttcc ataaatccat ccacctataa gagctgctgg
     1321 aaaagcaaca attatagaat aaagtataaa actacctaca tttgcattta catttgctgc
     1381 aactgccaaa ggtcctggtg taggtattac aagtgcatga cctactatag tcccaactcc
     1441 taatgcacat acaaaaacca ttagagattt cttagttact ctcgaaacat acttaattat
     1501 aggcatcatt ataacgaaag ctgcatccat aaaaactgga attgaaatta aaaaacctgc
     1561 tgtagttact gctaaagcac tgtttttttc tccagtctta gctaacaacc cctttgcaat
     1621 agattctgtt gctcttgatt ctgaaagaat atttccgaat attattccaa gtccaattac
     1681 aatacctata ctccctaatg tatttccaaa tccagtcgat attgtggttg agatttcatt
     1741 tataggcatt ctaaccataa agcctgtaat tatagatgtt ataagtaatg ccaaaaatgg
     1801 atttacttta aatttaataa tagatacaag taaaattcct atagatataa caaatgctac
     1861 caaaagtcca tatcctgtaa tcataatctt taccccttta tcattctact ttattattta
     1921 tcaatcttat ttttctttta atatgataat ttaaccttgc tgtatttata taatctaatc
     1981 ctaatagtat gtatttagtt atattgatat atttaagtat taattattgt gtttttttat
     2041 ttcaacacct gctaactttt caaaatactg tgctattcca ctatggtcat cttccaaatg
     2101 tccatgtact tttaatgtct gcataatttc taataattga cttgtcatag gtagtggtac
     2161 atctaaatta tgtgctgttt gcattacatt cttaatatcc ttcaaattaa tagatatttt
     2221 tccacctggt ttaaaatcac gattcataat cattggtatc tttgcatcca atattgtact
     2281 accagctagc ccccctctta ttgccttata tactttttct gggtctgcac cagcttttgc
     2341 cgcaagtaca aatgcctcag agactgccgc tatcgtcaaa ttaactatta cttgatttgt
     2401 aagttttgta acacttccac taccattatc tccaattaaa agagatgaac ttcccattat
     2461 attaaagaat ggctctactt tcttataaat ttcttcctta ccaccagcca taaaagcaag
     2521 cgtaccatca atcgcttttg gctcccctcc acttactggt gaatctataa attctaagcc
     2581 cctctctttt aatttatttg cacacaatac ggattctgta ggagtaactg aactcatatc
     2641 aactactata cttccttctt ttaaagtttt tgccaatcca tctgctccaa ataatacatc
     2701 ctgcacaata gttccatttg gaaggattgt aaatacaata tcacattctc gacccatttc
     2761 taaaacactt gcatactttg ctccacatga tataagttca tccacagcag atttatcaat
     2821 gtcatacacc aaaagattac atccatcttt caataaattt tttgccattg gctttcccat
     2881 tattcctaat ccaataaatc ctaatttcat tttatagacc tccatatctt cacatttttg
     2941 aaaacgtttt ttatgtttta gagtatacta cataccagta taccggtcaa tataaaatat
     3001 aaaagtattt attttaacaa taaatagtaa tttttaaagt tatttattat ttttagttat
     3061 tctatataag ttttaatata cactattttt taaatatcat atactacttt tacagttttg
     3121 tatttgaact aattttaatt aatctgactt tagtgttaat catatatcac acttcaacaa
     3181 ttttttatat tttttaatct tatatgcaat ttaaatttca aaagattgac cttattttta
     3241 ctatgttgta tgcttaaaat tatataagtt tttgtatttt tatattgttt aggggggtat
     3301 tattaagtat ggctacattt aaaagattac aagaacaagc atatgactac ttaaaagaat
     3361 tgatactatc tggagaaata atagaaaatg aaatatattc tgaaacaaaa cttgctagtg
     3421 aaataggcat ctctagaaca cctataaggg atgctcttca aagacttagt caagatggat
     3481 ttatagatat aatcccaagc aaaggattta gaatccatca aattacagca aatgaaatta
     3541 tagagatatt ccaaatacgc tctgcaatag aagggttttg cactttttta attacaagtc
     3601 aatacaaaga agctagggca atagaaacta taagtaaatt aaaacacctt ttagataaac
     3661 aaaaagatat tttactgggt gataaaaatt taaactcatt tgcagaatac gatacattat
     3721 ttcacacaac tatagtttca tatgctcaaa atactgaatt tgacaaaatg tttaacaatt
     3781 atatgtacag aataaaaaaa ttagctctcg attcattgtc acatgaggga agacttgaaa
     3841 caacattaaa agaacacaca gatattttta ataatattgc aaatggatgt attgaggata
     3901 tttacaaaac tactctaatt catatggaaa ctcctaaata cattaattta gaagatttct
     3961 gtaacaataa gttattttag cattttactt ttatttacta aaaaaatata tatcttaaat
     4021 taatttccta atttattaaa aatattctat aattatattg taactaatac tattctaagg
     4081 agtgattttt ttgaacgaag atgttgtaac taatgaaact atcgacaaag attatgctat
     4141 tgaagaagtt cgtatggcat gcaagcattt tggtgactta tatttttatt tttccaaagt
     4201 gttatttgaa gagtttggtg aagataaaac tagcgaaata ttaaaaaaag ttttatttga
     4261 aaggtctgaa gaaagagcta ttgctatgag agaaagagct catgaaaatg gagatgaatt
     4321 aattgcagac aatattatta gcacaactga tgttccattt ctaggatggg ttcctgaatt
     4381 tgaagagttg cattgccctt atggagcttc ctggctttta agatttgagg aaaatccttg
     4441 gtttaaaaag tttgcttctc tttattgtga tgttacagat actactgtag ctgaagtatt
     4501 tacaggagat acctcccata aaataacaaa aaacatttta tggggagata aaagttgtga
     4561 aagaatatat tttcatgatg acaaggtatc tgaaggtaaa tatacttatg gaaataaaaa
     4621 ctgtaaataa ataatttaaa ttttctatat tcatatacta tattttgtac tttttcatat
     4681 aaatattata actagtcttt tattttactt ttgtttaacc taaagataat ttacttttaa
     4741 tctatatgaa ttatcatata aataatcaga aagttatctt tataaattat agttttagat
     4801 ttataattta taaaatattt atgttctttg taaaattttt tagaagcttc taatgttatg
     4861 ctataaaact atctcaagaa gggctgattg aatgtttaat aaagtatatg aaaaaaaaga
     4921 atttatagtt tttcaagtaa aaaaaggtta tgtagtttat aatactagaa agagttttga
     4981 agaaggtcat acacatttaa agcattttga agcagcaaag acagctattg atttagcaat
     5041 aaataaaaag attcctagaa gcaaagatgg atattatctg actagtttaa ttcgtataag
     5101 tgatgatggt tattacattg ataagttaag cgaattgtta tatgttagag aacaaaaagg
     5161 taaaaaagaa aagtactgta attctggtta tcagatgtaa caagactagt tacgaattat
     5221 aagtaccaac cataagtacc tttggtctta aaatcaaaga gtatcagtaa atctataaaa
     5281 aacaacttac tgatactctt tttaattata tgattaatat ttgaatttga tacaaaattt
     5341 catacaaaag tttatgttat ctattctgat tctgtgtctg caaattggct attataaagc
     5401 ttttcataaa atccaccttt ttccatcaat tcatcatgat tgccctgttc tataatgctt
     5461 ccattattca taactaaaat caagtcagca ttacgaattg tagaaagtct atgtgctata
     5521 acaaaactag ttctaccatt cataagattt ctcattgctt tttgaagcat aagttccaac
     5581 ctagtatcaa cagaactagt agcttcatca agtatcaata ttgaagggtc tgatataaaa
     5641 gctctagcta tggttaaaag ctgtttttct cctaaagata tattagatgc ttcttcattt
     5701 aaaaacatat tgtatccatc tggaagagtg gttataaagt gatgaacatt tgctactttt
     5761 gctgcttgta taatctcttc tttagtagct ccaaatctac cgtattctat attttcaaaa
     5821 atggttccat taaataacca tgtatcttga agtaccatac caaacattga gcgtaaatct
     5881 ttacgtttca tatctcttat gtctactcca tcaattttaa tagcaccttt ctttacatca
     5941 taaaacctca tcaataagtt tattaatgtt gttttacctg ctccagtagg tccaacaata
     6001 gctaccatct gaccactttt tacttctgca tttaaatctt ctattaaagt tgaattttct
     6061 ccatatccaa aattaacatg ctcaaatgta acatttcctt ttacattttc tatcttaact
     6121 ggattttcaa catcaggtat ttcctcttct tcgtctaaaa tttcaaatac acgctctata
     6181 gctgcaaaag aagattgtat tactgtggat aattgagtca tttgtgaaag tggttgattt
     6241 atctgccata tataacgcac aaatgcttgt aaatttccta ctgttatccc tccacttact
     6301 gcatatatag aacctacaac tgccactgct gcaattccaa agtaagttac taatgaaacc
     6361 ataggattca tcatacttga tataaattgt gccttaaatc cattttcaca aagttcttga
     6421 tttacctttt taaactcttt tatagagtct tcttctttac catatagttt tatttcatta
     6481 aatccagtat acatttcttg tacttttcca tttaattttc caagagcatt ttgttgtaat
     6541 gaaaatctat tttgagattt ttttactaca aatttagata caaaataact aattggaatt
     6601 ataaaaagag ctataagagc catatatata ttaattgtaa acatcattga aagtgccaaa
     6661 attatgacta aaattgaatt tacaatttgc ataaaactct gttgcaaagc atttgatatt
     6721 gtatctacat catttgatat acgacttaat acatccccaa aactattact atcaaaataa
     6781 ctaataggca accttcttat tttattttct acttcatttc ttaaatctct cattgtgttt
     6841 tgaatagcat tcgtaagtag aaaacttgaa gtatacgtaa aaattgcatt ggcaacatat
     6901 atacatgcta aaatcaccaa tatttttgtt acatagtcaa aatttacgga tgctcctggt
     6961 attccttttg ctatactaat tacatcttta gtcaattgtg ttattatcaa tccctcagtt
     7021 ttaggtgcaa gtgcattcat agtagctgct gaaattatac atataatagc tataataaag
     7081 gaaaatttat atttctttac aaatggaaga agtctaccaa ttgttttctt aaaactttta
     7141 gactttttca ttattctaat tcctcctttt ttaactgaga tgttgcaatt tcatagtata
     7201 tttcacagtt ttttaataat tctttatgag ttcccattcc gacaacttgt ccttcattga
     7261 gtactataat cttatcagca tcaataatag aactaattct ctgagcgaca atcaatacaa
     7321 ttgcatcttt tgtttccttc ttcagtttag cacgaagtat tgcatcagtt ttaaagtcaa
     7381 gtgcagaaaa actatcatca aaaatatata tttcaggtct tcttataata gcccttgcaa
     7441 tagaaagtct ttgtttttga cctcctgata catttgctcc accttcacta atcaattcat
     7501 caaactttct aggttttttt gatataaact catatgcttg tgcaactttt gcggaatatt
     7561 ctaattctga ctctcctgcc ttatgtttcc caaatctaat attatttgct atgctaccag
     7621 taaaaagcag tgatttttga ggtatgaatc ctatcttttt tcttaaagct tttaaatcat
     7681 attctcttat atctactcca tttatcttaa tgctaccttc tgttacatcg taaaatctag
     7741 gtatcaagtt aattagagta cttttcccac taccagtact tcctataaaa gcaactgttt
     7801 cacctgtttt tgcagtaaat gaaatatcct taagtacaga agcttctcca tctggatagg
     7861 taaaagttac attatcaaat tctatgatac ccttattttc attctcctta attccatttt
     7921 caggattttt tattaatggt tcttcattta aaagttcttt tattctattt gcagatacct
     7981 ctgctcttgg atacataata aataccattg aaaaaagcat aattgaaaac atggcatgga
     8041 aaagatattc caaaaatgca accaactgtc caacttgaag ttctccaatg tttatcttct
     8101 cacttgaaat ccaaaataca gctaaaacag ctatgtttaa tagtaaaaag aatgctggtt
     8161 gagtaattga cataagctta aataatttct tagaaacatt agcataatat gtatttgttt
     8221 tttcaaatcg ctcagtttca taatcatcat ttccaaatgc tctaattact cttattccag
     8281 ttaaattttc tctcgatata aggtttaatt tatctagtcc tttttgttgc tttgaagata
     8341 ttgcctgaga tacttttgct attattgcta ctccaataat tataaaaggt actgatatag
     8401 ccaatactat agaaagttcc acacttgttc taattgtcat tattatactt atgatgaaca
     8461 taactggagt taataaggca gtccttagta gtatattaac aaattgttga atttgaaatg
     8521 cgtcatttgt tgttcttgta atcattgaag aaattccaaa tttattatat tcagtatgtg
     8581 aaaattcttg tgatttctca aatatatcat ttcttatatc tcttgttaca cttgttgata
     8641 ccttagcaga acaataaccc aacaatacac tacctacaac ccctataata gaaataataa
     8701 ctattactat ccccatttgt tttatgtaag ctatattctg atttgcaata ccattgtcaa
     8761 ttattttagc tattatggtt ggaatcccca attcgactaa tgcaaaacta aatatagcca
     8821 gtatgtttaa tactattaat aacttataat tctttaaata acttaaaatt aatttcatat
     8881 ttttctcctt tcttaatttt tgagctagtg taatcatata ataatactaa atttataaat
     8941 gcttaatttt ataaaaaaag gagaaaagag ttaacgcact ctcttctcca gcatattctt
     9001 tttaatacac cctccgacaa gtcgcttata tgttaacata tttgacaagt aatgtcaatt
     9061 catatagcca aaagtctttt aaatgcttca tttcataaca ttgtaacaaa ttggcatgta
     9121 atttattttt gttttttact gtattccaat tttacaagtt ctccaatatt actagctttc
     9181 ttaaaattca agttagtctt gtctatacca gacttaaata gtgaaattcc tctccccaat
     9241 attattggca atatatatat ataataatca tcaattaagt tatctttcat aaataatttt
     9301 actatatcgc ctcccccaac tatccaaata tcttttttat ctttctctct tccaatttgt
     9361 tcaattaatt ttttaggttc taagttcgta tactttacat tttcagttat ctcattaatt
     9421 atatttgagt atacatagca ctccttcccc ttatagtacc attcatttgg acttaattca
     9481 tttgcaatct gtacatatgt agaatttccc ataatgatag tatcaattgt atcgtaaaaa
     9541 gtattataat catcttcctg ttcattctta aagactgaag atatctcgtc caaaaaactt
     9601 acactgccat cttcttcagc tatataacca tctaaacttg tggcaatata aagtattact
     9661 tttcgcatgt ttactacccc tcgcatgttt actacctcca acatttatag tgtaattatt
     9721 ctatgcaaac atcacttttt tactcattca atgataccct attaataaat cctcaaacta
     9781 atttaaataa actttgcata aaattaaaaa tatgttatat aaataattta aaactccaat
     9841 aatttattga aaattctaat tattacaaat aaacattgct ctctgttcat gctagtttta
     9901 taatataatt ataagctatt aatattataa agccgatatt actaatataa taattataat
     9961 acttatagtt aatttacttt tgttgaaagg tggtaaataa catgaaaatt tcagaagttt
    10021 ctactccaaa ttttttgcta gatttagacc agttagaaaa gaatatagat aaaattcaac
    10081 aaatttgtac aaataataat aaacaacttt ggcctatgct taaaacacat aaaagtactt
    10141 acatagcgag acttcaaaaa aatgcaggtg ctagtggttt tctagttgga acacttgatg
    10201 aaggtgaagc tttgataaaa gcaggttttg aagatattat gttggcttat ccttacatgg
    10261 gagaggtaaa tataaataga attgttacta tggcatcaaa aataaattta atttgtgcta
    10321 cagataatat agaatgtgct aaggcttata gtgaagcttt ttctaaatca aaactagagt
    10381 gtaaactact tattattgta gattgtggct tacaccgttt tggggttgaa ccagaaaaag
    10441 tggttgaact tgctactgaa atttctaagc tagaaaacat caagattgtt ggtataagct
    10501 cacatccagg tcaagtgtat ggttgtagct ctccagaagg tgttccagat gtttgtgtcc
    10561 aagaagattc ttctatggag aaagcataca aagctctaac tgataatgga tttaatatag
    10621 aaattgtcgc ttctggtagt actccaacag ttgaagctga agctgtttct aaaactataa
    10681 ctgctgtaag acctggaaac tatgtatact atgatgctat acagataggt ttaggttgtg
    10741 ctactgaaga tatgtgtgct cttactgttg tgtgcactgt aatctcaaaa aatagcagtg
    10801 gatactattt aattgattgt ggaagtaagt gccttggact tgataaaggt gcacatggaa
    10861 acagtagtat tgttggttat ggtagggtat gtggacatcc agaacttact attgattcac
    10921 tttcagaaga agttggaaaa attaaagtaa atggtgaaac tgatataaaa attggtgata
    10981 gaataagaat tatacctaat cattcttgtt ccactgcaaa cttgacgagt aatttattag
    11041 gttttagagg agatacaata gaaagagtca tagaagtaga tattcgtgaa aattcaaagc
    11101 aaatcatact ttaaaaatac atttattttg gttttagcga aagtatattt ttctcaaaat
    11161 tattgttaat aactaatgtc aatgttgtat aaataaaaac ataaattcta gaaatataaa
    11221 tttaaaagaa gaggctatct caaaatagag ataagcctct ctttcattgt tgaaattatg
    11281 aaaatatact ttatttcata taaatggatt tgtatgtagt ggtatagttc catatagtga
    11341 acttataata aatataaaag acataaaagt accattaaac tttttaaagc ttgatgaaag
    11401 agatttttat aaatacttat tcaaactatt aaatagtcaa aaagatattg actttacaaa
    11461 atcatttatg gattttttaa aagaagacaa caattattat gatatatatt cattaataga
    11521 ttctaataaa tgtccatata caatcaaaga ttttaacatc cctcaacctg tgtatgactt
    11581 taaaaaatta aatgataaat tattggaaat acatttagac ttattgcgag ataataagat
    11641 taacctttct tttactagaa attacatcat tagttgtgaa cttaataagc ttggatatga
    11701 ttgtatttac atggttccat ctacagaatc aatcttgaat acatttaaat ctctggtgaa
    11761 tgaaataaca ttacaaaact tagacaaaaa taaatccgca acttgtatag ttacagtaaa
    11821 tagttcagag tacataaatg aagatttgat atttaaaaat gatgagatac aaaaccaaat
    11881 atataacact atcttaaatt ctctatcaag acatggattt tatggagtcc aggtcaaaaa
    11941 aaatgatatg aagatagaga tacatactac taaggaaatg ttaaacaata tgaccaataa
    12001 ctatacagat ttttttattt cagaagattt aaaagaaatt aaatatagct taaatatagg
    12061 ttggggtatt ggaaatacaa atattcatgc agaacaaaat gctagtcaag ctaatggtaa
    12121 atctgctgct ctaaatggaa actgtacttt tatagtaaat gatactaatg atacaatagg
    12181 acctttgtat tcaaataaaa attctaatac tattgaagat agctcaatag ccaataaagt
    12241 tgcttctttt atacctctat ctaatacaaa tgtgtctaaa atcatgtgta tgattaatga
    12301 tagaaattca aataatgtgt cagcagaaat attagcagac tatatgaaca taactcttag
    12361 aagtgctaat agaatattga gtatcttata taaagcagga attgcaacta ttgtaaatac
    12421 aaaactcgat aatcaaagag gaagaccaaa aaaaatatat aaaattgatt tcttatcttt
    12481 tctaaataag atgcagaaat taaattctta atatttaaat ttttaataaa agcaatgtat
    12541 tttctctaat tttaaagaat caaaatgttt aaattttatt agaatataca actttttact
    12601 ttaaaatacc taaatctttt atcagtgaaa taaaccataa tatatcgtag cttattagaa
    12661 aaataaaata atttcatata caaataataa aatggccact acaatccata atttgcagtg
    12721 gctacttttt acactatcac ttattactta tttttaaaag ttaattatat tttttaaata
    12781 atttatacac gcctattatc agtaaagcaa taaatacaaa tatatctata aaaataatta
    12841 ttgtaacatg tctggcaata ttgtaaataa aaagtataga gaatatttct atagacaacg
    12901 ctacaaaaca cataaaattt gttaaataat ctgcaatagt atcactataa aaagcatgta
    12961 tttgtaacca tctccatata aatggacgta aaaggattct gaatacaaca caaatagcag
    13021 gataggcata aataaatttt ttatccacat aattagctac accattattc cattggatag
    13081 gaatttgatg tggcaacttt ggaaatacta ttattgcaat caacaaacaa gcaatagtaa
    13141 taattcccca ggtaattttc cttccccata tatataagaa acttacagag tcaagtttaa
    13201 aaacaggttt gtttttattc cagtattctg gcaactcagt tatgtattgc tctactttca
    13261 aattcaaata acttagctca tcagactcta acattttatt acacatagtt tttgcatttt
    13321 ctaaatctga tattttagtt tcgagaactt tctcctgttt ctctacaact tcaactaaag
    13381 atactttctg taatataata ttacggatat catcaatagt aattcctaat gtacgtaaat
    13441 atgcaatttt tttgatgtcc tctatatttt catctgaata ttctctatag ccattacgct
    13501 cattacgaag gggtttaatt aaattttcgt tctcataaaa acgaatatta gagcgtgtca
    13561 atcctgtttt ttcttcaact tctttaattg tcattttaaa cactacctct ctattctatt
    13621 aatttatagc tataatatag tcttaaatac tttcactcta taaaattgta tgtttattat
    13681 gtcttaaaat caaactaatt accttttata aattttcata caataatatc tcctttcaat
    13741 aatatctctt tttctatatt taaaactatc ttattttcta taaaataatg tataaacaag
    13801 gtttacagtc aagtattttt attatttttt taatttcata aaaaaagcat agcaaatcat
    13861 gtgctatact ttttattgga ttattgattc tatatcctat ataaactctt tatttaactg
    13921 ttacatagta ctagctttaa tcatcatatt ttttgcaaat acattagctt catatatttc
    13981 ttgttcatct ggatgacttt gagattcctc atggttattt aattgttggc gaatatgttc
    14041 gttatcagga gaaagtttta acatttcttt atattttact ttcaatcctt ctgctatctt
    14101 accttgacat atgaatgaac ctaatatttc attatctttt ggaataattg attctatctt
    14161 ttctattata ctagctccat aacttccttt tgtacttgct cccattgttc caaatagtgc
    14221 tatcttttta ttgtgaatat tttcaagtac ttgttttgaa tttttatcac aaattccctt
    14281 atctacccaa tagcctaaga atactatatc ataattttca tagtcaatac tatcatcaac
    14341 taattcactt atatttttaa tttctttttt cccttgaatt gcctcatata tagaacaggc
    14401 aattttttta gtatttccag ttaaacttga atataagatt aaacttttca tgatgtatcc
    14461 tcctatttat ctaaataatt atctaactta caagaaaaat attaacagat tttttatttc
    14521 tacaaacaca atttaatcta agatacatcc aaattgagaa tgtgtctgca aggcatctgc
    14581 acacttttta ttacaataac agcatttttt aatctcatct actcttccat cttttacttt
    14641 ctgtaaccaa ttactatctg ctagtaattg tcttgacata gaaatcatat ctactctatt
    14701 atttgaaata atactttcta taaaatctgg gctagacaat tttccaaccc cacatactgg
    14761 aagatttgtg tgtttcttta cttcatcagc taaatataaa aaacaacctt catctttaaa
    14821 gtaaggatgg ttattgattg gtatagtatc ttccaatttt gaatgatttg caagtgttac
    14881 atgaaaactg tttacaccta gggattcaaa ttttttaaca aaatactcaa cttccgaaaa
    14941 taaaactcct gcattcccat aatgaggatt ttcttgtctt attgcaaatt tatagtctat
    15001 tggaatatcc ttaacttcat ttcggatact actaattatt tcacttgcaa atctgcttct
    15061 attctcacat gttccaccat attcatcatt tctattatta aatatacttg atgaaaaact
    15121 tcctataagc ctatctccat gaatttgaat catgtcaaat cctgcttttt ttgcatttaa
    15181 tgctgttact ttaaataaat ttataatatt tttaatttct tctttgggca tatttgttat
    15241 gtaatctttt actccatcat tcattatttt ttttatctca acatgtgaag taattcccat
    15301 cttcatagta tctttaatta aattaacatc ataatctgaa caaaatattt gtgctgatac
    15361 ctttgcacca gaattgtgta tttcgtctac gatttttttg tatttcataa ctccatcttc
    15421 atctgtcaag ctcatagcca tattatgaaa gctaggtcta acagatacat ctcctaaagt
    15481 aattaaagct actcctgact tagcaatatc acaaaatttt ttaatttttt cttctaattt
    15541 aagtcccatg cttgtaggtg caaatgatac tctatttttt aattccaaat ttccaatttt
    15601 aattggcttt aacaaattac aatacatcct attcttcctc catagctgtt tttatatcct
    15661 ttaccacatg taatttcttc actaattctt tatattcttc atctgagaac tcttttttta
    15721 tccggttatc ccattttgaa aatatatttt ttatatctcc taatacttcc tctcccttat
    15781 ctgttactct caactgaaaa gctctgctat cattagggtt ttggattttt tctatgtatc
    15841 catcttgttc taatctagat atagttcttg ttgtatgagc cttatcaact tcaaattctg
    15901 tagaaacatc attcaaagaa caatttctat ttttattaat atagattaaa taaaaatata
    15961 gaccattagt aagtttatat ggttttaaac atttttcaca ataaagttta aagttttttt
    16021 gtaaattaca aataatatat gacaaacttt catactgcaa atttttaaaa tccatcttaa
    16081 atttcccctc tataattata atatatttga ctatatcaac tatattatat taaacaatta
    16141 atatagtcaa gaatatttta ttatctaaat ctatatttta ttaattcttt acaaaactat
    16201 tatataaaat aatcatgatt aaattagaaa ttggaatttt taatatgtac tatacataaa
    16261 tatattttat ataaaagttt atattttcaa acaaataatt ttccgaaaat tgtctaaatt
    16321 cagtaaaaat atggtaatat atacataagc aatataaatc tataaaaagg agtgttacat
    16381 atgatatcta ataaaatgca aactttagtt gcaaatagtt ccgttataag agctatgttt
    16441 gaagaaggaa agaaactttc tgatatttat ggtgaagaaa atgtttttga ttttagtata
    16501 ggaaatccaa gtgttgaacc tccagagact attaaagcag ttataaatga tattttaaat
    16561 gaagaatctc caaatttagt tcatggatat atgaacaact caggatatga ggatgtaaga
    16621 gatgctattg ctgaacatat aaataaaaaa gatggattaa atcttacaaa agaaaattta
    16681 attatgactt gtggtgctgc tggtggtcta aatattattt taaaaactct tttaaaccct
    16741 ggtgatgaag ttattgcttt tgcaccgtat tttggtgagt ataaaaatta tacagaaaac
    16801 tatgatggaa aattaataga agttcctaca aatatagaga cttttgaacc agatttagat
    16861 gctctagaaa atgctattac accaaaaaca agagctttaa taataaacac tccaaataat
    16921 cctactggtg tcatatattc tgaagaatta ttaaaaaatc ttggagaatt attggattca
    16981 aaacaaaaag aatttaatac aaatatatac ctaatttctg acgagccata tagagaaata
    17041 atttatgatg gtgccaaagt tccttgcgta ctaaaatact atagaaattc atttatagga
    17101 tactcttata gtaaatcatt atctctacct ggtgaacgta taggatatat tgttgctaat
    17161 ggacaaatgg atgattttga tgatgttatg tcttcattaa atgttgcaaa taggatactt
    17221 ggatttgtaa atgctccatc tcttttccaa agagttattg caagaagttt agatgctgaa
    17281 gttgatgtaa atatttataa aaagaatttt gaccttctat ataatagttt aatcgatatg
    17341 ggatattctt gtgttaaacc tagtggtaca ttctatttat tcccaaaagc tccaattgaa
    17401 gatgataaaa aattctgcaa tgatgcaaaa caatttaatt tattattagt accaggttct
    17461 tcttttggtt gtccaggtca ttttagagta tcatattgtg tatcttatga caaagttaaa
    17521 agctctttac cagcatttga aaaattagcc aaattatata atttaaaata attaaatcaa
    17581 agtaattcaa ataattaact accttagtat agaatactta cattctatat taaggtagtt
    17641 tataatttta tgtactatat tttatacata ccatattatt ccaatatact tgaatattct
    17701 tatctatagt actaatataa attacaagga ggtgtttgac ttgaaaaaag gttatgttta
    17761 tataatactg actaccttat tttttagttc aatggaaatt agtctaaaaa ctgtcactaa
    17821 tgactttaat cccttacaaa taactttatc aagatttttt gttggcggtt tagtcttact
    17881 accttttgct gtaaaaagat taagagctct taatctttct attacaaaat cagacttaaa
    17941 atactttgca tttttaggtt ttatgtgtgt agtagtaagt atgtcattgt atcaactggc
    18001 tgttctaaac acaaaggcat ctgtagttgc tgttttgttc agttgtaatc cggtctttgt
    18061 aatgctttta gcttacttaa ttttgaagga aaaaatatat aggcacaatg taatttcact
    18121 tatattagaa gttcttggaa ttatagttat aataaatcca ttgcatacaa aactaactct
    18181 tagtggaata ttcttaacat tatcttctgc tattattttt tcaatgtata ctgtatttgg
    18241 taaaagaaaa accttaaaat ttggtggaat agttgtaact tgctttagct ttatatttgg
    18301 tagtttggaa atgctgatat tggttttact cactaaaatt aattttatcg cagatatatt
    18361 aagtaaaaat aaacttaatg tatttgcaaa tatacctatt tttagtggat ataccttaca
    18421 caatatgcca attatgattt atgtattcgt atttgttaca ggtgttggtt atgcacttta
    18481 ctttatggca atggaagcta catctactag tcttacatct ttagtcttct tctttaaacc
    18541 agtaatatct ccaatactag cattattaat acttaaagaa attatcccta taaacatgat
    18601 tataggaatt ttattgatag taattggttc aataatttct attataccta cgataattac
    18661 tcaaatgcat aataaacatg ttgaagcctt gtataaggag tagtaattga tactctatca
    18721 gtttatacat aagacaaaat ttattagttt taaacgcaat ataaaagaga tgctattaca
    18781 atagcatctc ttaatttata tttattttaa atttattaaa ttatctattt agctaggttt
    18841 tgtaaaaaac tataagtttg tggacaagct gattttaact tactatttgt atcttgattt
    18901 agatagtaat acgcaaatgc ttctgcaaaa aattcttctg gatatacacc taagtagttt
    18961 acattcccta aagaacgtcc ttctttagca aatatttgtt taaattgtgc tgatttagat
    19021 atatcattta atactatatg gtctattgca tgtgctgttt catgtaattc taagtttatt
    19081 gcatcatgac ctttaccttt gttactaaat cctattctaa gagctactgt gcttccacct
    19141 aaacccggaa catcatccca agtttttcca gttccttccc atcccttagg aactacacct
    19201 tttaaataag catattcttt ttcatctgtt agctttccac ttaataattt tatttttaag
    19261 ttattttgat ttaatacatt taaatacttt ccatctatat tagctagtct atttaccata
    19321 gcattagctt catttttatc gtaatttcca gttggaaaaa ctactatctg actaagtata
    19381 tctttatttt gttgtatagt agtactctct gcatgtgcac ttactggaac tgaacttatt
    19441 aagaatattg atattatagc tattaataat tttttacttg gtctcatatt attccctcct
    19501 ttgagttagg ccgggagtaa taaatttcaa aataaaaaag atacccaaga gtatctttgt
    19561 atatacaaaa agaaattttt actcttttcg gcaactggct ggcatggttt actaaacttt
    19621 agcccctata gctttgcgtg actaggtttc cctagttttg cctcatttaa ttttatatct
    19681 atattatagc ttatatcttt ttaattgtct atgctcttta gaattttttt ctaaaaagtt
    19741 attatttttt tacataaatc ttcaaaaaaa aatatcttct aacaatattt tcactattaa
    19801 atattatttt agaagatatt ttttaatatt acttacattt tttataatgt tagggtctaa
    19861 tttgcatttt tatttctttt taatacgata agtcctacaa tagctcctag aactaaaagt
    19921 atttctccaa taattgtagt attatcccct gtctttggtg gtactggtgg atttaccaaa
    19981 gtatcatctt taactttatt atttttttct tctgatactg atggctttac tacttctggt
    20041 attggaacaa tctgtttaac aggagtttct atcacctctt ctgatggtgg tattggtgga
    20101 ttaactacct ctggtattgg tggatttgtc atatcttctg atggtggtac tggtggattt
    20161 ataactacag tttcatctgt atcagatgga cttgatggtt tttttggttt atctgtgctt
    20221 ggtggcactg gtggatttac cactggttca tctgtatttg gcggtactgg tggattttct
    20281 tgtcttatgt tttctatatt tccaatatcc actattctac caatatcttt attaccaatt
    20341 tcaaccttaa ttttatcctt caatttttca tatccatttg gaggcctaaa ttccaccaaa
    20401 taatatattc ctggtttttt tacactagat tgaattacac catcttcatc actaactaaa
    20461 tccttaacta ctatatttcc agaaacatct tctaaattga acctagcacc tgaaagtaca
    20521 tttttatcta aagcatccac ttttttagct tcaaaagcat aaccttgctt agtagtctct
    20581 actcctggag ggcttgaacc attaatctga gctatatttt gtatagtctc cccaactttt
    20641 acatttgtga agtctgcatc aaatgtaacc caactttgca caggttcacc ttcttttatc
    20701 tgtttaaatt cgtatttatt tactaatctt attgtatttt ttccatctcc agcttctttt
    20761 ttaagttcaa ggttatcaga atattttata ttagatattt ttagagctgg atttacttca
    20821 tctaaaagat ttacttgccc tgcatcataa accccataag ttgacatatt gattttgtat
    20881 ttaacaatct gattatcact actacttaaa acctttttat caacttcttt ttttgcgctt
    20941 attaatccag aatttttctt aaagtttatc tcatcatttt tatcaatttc actattattt
    21001 gcatcaagaa cagctctatt tatatagcta tcttcaatac taattacctt taatgtataa
    21061 gctataaaaa actttgattc tacttcttct ttactaagat taattgtaaa tccagttata
    21121 actttatcga cttgcccact ttcatttctt ttttcttcta ctttatatga aatattgttg
    21181 gcaatttttt ctttactcca aggagtccag ctaccattca ttggaacttc tacaactcta
    21241 aaatcatgtc cagcttctcc tgaagtagtc aatctcatac cttctggtat attatctgtt
    21301 ataacaacat tactgattgg tgacttatca tcatttactg aaatctgata gtttattact
    21361 tgaccaactt gagtaatatt tgttgcccct gaatgtcctt tagtgagaag ataattatcc
    21421 cctctatcaa acacacttac agtagcatca tcttcttgta tcttcttccc atcagattca
    21481 atcctagcta cattcttata tttattgcca tgttttgcat ttttgtcact gattctagcc
    21541 ttatatttaa cagtatacga tttatctata tttccaaaat taactgaaat agagttttta
    21601 ctctgtgtaa tgttaaaatc actaacttct tttccatcac ttgttactac acttacagag
    21661 ccatttatca gtgtcaatcc ttcaggaagc tcatcataca aaataatatc ttttaactct
    21721 tcctgctttt catttacttg tatactgtaa tttatatctt tatttttaac tggcataaat
    21781 acagtagttg attttcttcc ttcaacaagt ttcttaagtg ttcctttagc atctggaacc
    21841 tccgttttgt ctccaggttt tatttctaca tctacatctc cacttccatt ttctattttt
    21901 ccagtggttt caatatgtat ttttgcatta gtatcttcat caactttttt aacatatgct
    21961 tccaaaccta ttttcccttg cattatactt tggccattag gtaattctct aaatgtaagt
    22021 gtatactctc cattactttc tgttttatcg aaacattcac ttgtataatc taaattaact
    22081 ttattgaata catctggaac cttaaaagtt attgaatctc ctgcttgtat tccttttgaa
    22141 gttggagtat aagttaaatt aaatgatatt tttttcattg attccgtttc tattgtattg
    22201 ttattaattt ttacaataaa tccatagtct tcattttctt cattaagttc atcttctaaa
    22261 actttcaata aattttcttc ttctaatagt ttctcttcct ttggagtttt ttctggattt
    22321 ttattatcta gtgttttttc atcttctaaa gattgttctg actttttatt atctgttgac
    22381 ttatcttctt gtgtatgctc tggattttta ctatctattg gcttttctcc tactggagtt
    22441 tgctctggat ttttattatc tgttggtttc tctttctctg gcgtctgttc tggattttta
    22501 ttatctgttg gtttctcttt ctctggcatc tgttctggtt ttttgttatc agtttgcttt
    22561 tcttcctctg gagtttgttc tggtttttta ttgtcgcttt ccttttcttc tccagtggat
    22621 gaattagttg aaccactttg aatctgacta ttctctccta attctaaagc ataagataca
    22681 gttggatata ttgtagacat caccatactt aaaatcataa ttaaactaat taataatgcc
    22741 tttttatttc ctttcctcat ataaatttct cccctctagg ttatctatac tttctaatct
    22801 tccattaata tcatatataa attaattttt actaaaaaat tatacaaaaa aagctatgaa
    22861 aataaataaa tttatattca tagccggttg caccactgac tcagtatatc cataaggtgc
    22921 ccaataatag aatatacttc aacatctcta taatatttca taaaaacaat taaaattgtt
    22981 tcatttatat taaaaataca attatatact tctattatat tatgccttta tactattgtc
    23041 tatctttttt acatttttta ccttattatg agattaatta ataattaaat aaaatcctta
    23101 tctacaacaa ttacacaatc atattcagga tttatctcct taactaattt tgttatatct
    23161 tcttttaagt catcctccga catgtttttg gaaaattcgg aagggttaac tactatatca
    23221 aatattaaat tcttcttgct cccctttcca actattctaa aatcatgcat agattttaca
    23281 aggctatttt tcttaagtat ttcttcaagt tcttttttgg ctgacataac ttctttatct
    23341 tcaagacata ctgggtccat gtgaattact agatatatat ctaatttttc agatatttct
    23401 ctctctgcag tatctataat ttcatgtatt tccattatat ctatgttgga tggaatttct
    23461 gcatgtatag atgcaataca tctaccgact ccgtagttat gaataattaa atcatgtgta
    23521 cctattatat gtttataaga taacaatagc tctataatag aatttaccat atcttcatct
    23581 ggtgcttctc ctagaagagg atttatagta tcttttacaa gagagaaacc agcataaagt
    23641 atcactaatg atactacaat accaacatat ccatctatag gaaaattagt aaatctagct
    23701 acaataaacg atataactac acaacttgaa gtaaatacat ctcctaaagc atcaagtgaa
    23761 actgctttta atgctgaaga atcaatttta tttcccataa atttattaaa acggctcaac
    23821 cagattttaa tcattataga tgcaattaaa agtataagtg gtattacttc aaattttata
    23881 ggaactggat ttactatcct ttctatagat gactttacaa attgaagtcc aaccaacatc
    23941 accataaaag ctactattaa tgctgataaa tactctattc ttccatgacc aaaaggatgc
    24001 tctttatcag ctggcttact tgctaattta aaacctatca tagttattgc tgaagatgcc
    24061 atatcagaaa gattattaaa tgcatcagcc attatagcta tactggatgt gagcattcct
    24121 atgaatactt ttatcacaaa taaaagtaaa ttggataata tgcctactac accagccaca
    24181 taaccatatt tatttctaac atctctattt tgaacgtttt cgctatctct aataaatgtt
    24241 ttgactagga ttttggaaaa catgaaactt acctccttgt cctttatttt attaacaaat
    24301 tttagaatct atatctttat ttatgataac ataatttata tataaaattc ttaaaaaatt
    24361 actatacttc aataaaatat tattatatat caatttaaat acaaatcatt atatttagca
    24421 aagtttttat gccttaatat ctgcttaata cattctatgt cattttttaa aaagattatt
    24481 tattacgata atatcatttt tcccaagtat tccttagaat atgatttttt tattttgtct
    24541 atacatattt taaaattata ctgtatttat ctatatttta taaccttatg atacactata
    24601 actataagat tttaaacgga aaggaatgaa ataaatcatg ttttttatca gtgatattta
    24661 cacaaaatca cccattaaat ttgatacttc attgcaaaaa gaggtatata aaatattaca
    24721 aaagttaaat attgactttt aacatattga cacagatgaa gcaattataa tggaagattg
    24781 tgtttagatt aataaaaaat taaatatgaa aattaaaaca aaacaaatca ttcatgattt
    24841 cttatctttt gcaggtcata caccatctat aattgaattg taatataaaa tagcataaaa
    24901 aaaacacaaa ccgcaaagtc acaatatatt ggtactttgc ggtttcataa gaattaattt
    24961 ttactattac agttcatagt tctactattt ttcatcattc tgagtattag ctttacaaat
    25021 tcatttgaca ataggatagt tgatgcaaat agtattattt ttatccacat atcaaaatcc
    25081 aaagaaacag aattaaagaa actctggaac acttgtgtaa atattatttg aattatccct
    25141 gtaactacta ttatttgcaa tgccagttta tttttaaaga aatttggtat tgtactattc
    25201 aaaccaaact ctctacaatt taatgcatta aaaagggcac tgaatgcaaa taaagaaaat
    25261 ataacagtac cttgttcttc tgatgtagct cccaatatat tgaaagctga ttgagcaaat
    25321 acaattgtaa ttataagaat agcatttata ataatattta caaacataga cctagctatt
    25381 attccagaat gtctatttat tggctttctt ttcaatacat aatctctaac aggttctaat
    25441 cctaatgcta aggctggagg accatccatt attatattta cccataataa ttgtattgta
    25501 gtaaatggca tatccttacc agtaagttga gatattatag caattataaa tgctactata
    25561 tttacagtaa gctgaaactg tataaatctt tgaaagttct catatatacc tcttccccat
    25621 tttattccct ctactatagt actaaaacta tcatcagtca atattatatc tgctgcattt
    25681 ttagatactt ctgttcctga aatacccatt gcaattccaa catctgcttg actaagagct
    25741 ggggcatcat ttataccatc acctgttaca gctacaactt cgccactttt ttgaagtgct
    25801 gaaactattc tcatttttgt atctggttta ctccttgcaa caatagatat tcctttgatt
    25861 tcttctctca attctttatc tgtcagtaca tctatatagg ttgcttcaac tgccttttta
    25921 ccatcattta ataatcctaa ttcatttcca atagctgttg ctgtattgat attatctcct
    25981 gtaagcattt ttacatctac tcctgcatta aatgctttat caatggactc tttgacacct
    26041 tctcttaatg ggtctattat tcctacaaat ccactaaaaa ctaaattatc ttccttcatg
    26101 taacttcttg agcttcctat taagttcaat tcaccttctg aagttattgc aacttctgtt
    26161 ttagaattac tcattttttt ataagcaaat cctaatgttc tcatagattt aatttgtaat
    26221 ttcttaatct catctaaaat acttttctct atttttgaag ttattggaac aatatttttt
    26281 ccttgttgca cataggaaca tttttttaat aatacttctg gtgctccttt tgaaagcaat
    26341 atatctgaat cctcttgacg aattaatgtt gacatcttct tttcttctga actaaatggt
    26401 atttgtgata tcaaatacgt ttgttttctc atttcattat agttcttatc attatgatat
    26461 aaaagtaatg cacactctgt tgcacttcct atatatttaa atgaattatc ttctttttct
    26521 atatctgcgg ttgaatttac tatacagttt tgttcaaaat agctgttact ttgatactct
    26581 cctccactta tatatttacc atcaacatat gctacctcta ccatcatttt gttttgtgtt
    26641 aaagtccctg ttttgtcaga acatattaca gaaacagaac ctatagtttc acaggcttct
    26701 ttctttgtta ctagtgcatt tatctttgcc atcttttgca ttgttatagc taaagtaatg
    26761 tttatcatag ttggcaaacc ttctggaaca gttgcaacta ttaaggcaat acaaaccata
    26821 tatgcatttt tagcaggttc taatgattgt aagaaagata atacactgct tgtatctaaa
    26881 attaacatac cttttctctg catctgtata atcataaaca tacacaataa agtagctatt
    26941 acacctgata ttcctgctat tttagctccc aatttcccta atttaatctg aagtggagtt
    27001 tgctggtctt catttgataa attctgtgct atcttaccca tctctgtctt atctccagta
    27061 tgagtaacga ccattatgcc tctaccatat gctacaagag tccccccaaa taccatattt
    27121 acttgctttg caggtattgc atcctgttcg attatttctg ttttagaata aacaacttcc
    27181 atatctaata cagcatcagc attcttagct acatcatcag attctcctgt taacatatct
    27241 tctctaagtt tcaaatttat agattgtata agtcttccat ctgctggtat catatctcca
    27301 gtttctatat atacaatatc acctggtact aaatcatttt ttgatatttt aattatcttc
    27361 ccatttctaa gtacttttac ttctatattt tctgttaatt ttgacaaggc ttgagctgct
    27421 tttttagatt ttccttcagt tattatacct atagaaattc caataaaaat agcccctaaa
    27481 atacctaatg catcatgtag ttctcctaca aaagaactta ttactgctgc tcctatgaga
    27541 attaatatca taggctctgt caaactttct cccaactcgt cccaaaatgt tctaccttct
    27601 tttatagtaa attcatttaa tccatatcta agcttccttt cttctacctc attatcatca
    27661 agtccaattt ctggatttgt ttttaagtat tttaagactt ctttggtagg tttattataa
    27721 tacctcataa ctttatcccc cttgttaatt atctataagg aattatatgc ttatgatagc
    27781 ttgtatatta cttttcaaaa aaataaggtg ttgattaatc aacaccttat agtggttata
    27841 tattattaaa ttttatgtta taggctttat aaattgtgag ttatataaat caaaatattt
    27901 aatcttcaaa gtacccttct ggatataatg ggaacttaga tataagttct tgtgcttctg
    27961 ctttacattc atctaatact tccttattat caatattttc tgctacctta ttcattattc
    28021 ctgctatctg tataacttct ttttctttaa gacctctttg agatattgat gtaagaccta
    28081 tacgaacacc actagttacg aatggtgatt gtgggtcatc aggtataaca tttttattaa
    28141 ctgttattcc tacatattca agagcttttt caaattgttt tcctgtaaga ttcttgcttc
    28201 ttaagtcaac cattactata tgattatcag ttcctccact tacaatacta aaaccatgtg
    28261 aaatcagttc agaggctaga gtctgagcat ttactacaac ttgttccatt atctttttaa
    28321 atttatctgt acctaaatac aatagtgaaa aggcttttgc tgccactgta ttaagatgta
    28381 tagaacctaa tgttcctgga aaaacacctt tatcaagttt ctttgcatgt tctgctttac
    28441 aaagtataat accacttctt ggtccacaga aagtctttgt tgtagatgaa gaaacaaaat
    28501 ctgcataagg tacagggcta ggtattactt tagctgcgac taatcctgca acatgtgcca
    28561 tatctaccat aaagtaagct cctacttctt ttgcaacctt tgatattctt tcataatcta
    28621 ttaatcttgg gtatgaactt gcccctgcaa ttataagttt tggtttacat tcttttgcct
    28681 ttgcttcaag agcatcataa tctatacgtc cagtatttgg atccacccca taaaattcat
    28741 atttataaat atcatgtaaa aaattaactg tgctaccatg tgttaagtgt ccaccttggt
    28801 caagacgcat acttaagaca gtgtcatttg gttttaatat tgatgaatat acacaatagt
    28861 tagctgtaga gcctgaatac ggttgtacgt ttacatgttc tgctccaaat acttcttttg
    28921 cacgttttat tgctagagtt tcaagtttat ctgcttcttc agaacctgct tgaaaacgag
    28981 cccctggata gccttcttct gttttatttg taaatacaca tccacttaat tcaagaactt
    29041 ctgttggtgc tgtactttca gaagctatca tctcaatatt atgttcttgt ctaaccaatt
    29101 cgttagctac aatcttgtat aactctgggt ctgaaatttt tgttgttttt aacataataa
    29161 tcctcctctt aattaaagaa tatattttat tagattaatc tttattaata aatttattat
    29221 aatggtctat aaaacgtaag atattcctcc accaggtcct aatggtatgc caatactcat
    29281 gaatagtaac aatattatta cctctattaa tgtaaatact actgagtatg gaatcatatt
    29341 cgatatgaca gtgcctatac ctatatcttt atcatatctt ctggcaaaag ctaatataac
    29401 tggaaaatac ggaaaaagtg gacttattgg atttgttgaa gcatctccaa tacgataagc
    29461 tatttgagtt aatgctggat taaaatctag tagcataaac attggaacaa atataggtgc
    29521 taaaattgcc catttcgcag aagcacttcc tacaaataaa ttgataaatc cagataacaa
    29581 tataaatcct attatcaatc cataactagg tatccccgac tctgccaata cttttgctcc
    29641 tgttattgat aaaattgttc ccaagttact aagattaaat aaattaataa attgagatgc
    29701 tataaatgct agaactatat atcctcccat atcactcata ctactaccca tcatagatac
    29761 taattcttta tcatttttta tcttattact tactcttcca tatactaacc ctggagttaa
    29821 aaatatgata gtaattattg gaactattcc cttcattaaa ggtgcattgc ttgataatat
    29881 agaaccagtt tctgggtctt tcataaatgc attttctcct atacataagg caactattat
    29941 taccacaata gctaatagtg ataatagagc gtactttata cctttatttt caagctcact
    30001 taattcctcc atatccttat catttactgc atcactatat tttgaaaaac gaggagctat
    30061 aaatttttct gttacaaatg ctcctgcaaa agtcaaaatt attgctgata caaaagcaaa
    30121 ataaaggttc attgctggat ttccttgata agatgaatcc atcatttgag ctgcaggtat
    30181 tgtaaatcca gctaataata catctgtagt actaagcata acatttgctg caaatcctcc
    30241 tgcaacccct gcaaaagctg caaacatacc tacaagagga tgtcttccaa ttcctaaaaa
    30301 cacaagtgct gcaagtggtg gtaatattat aaatcctaca tctgctgctg tatgtgataa
    30361 catacctgca aatacaattg ctacagttac aagtttttgt ggaactttac ttatcccttt
    30421 tttcattaac acttccataa atccagattt ctcagcaaca cctgctccaa gcattgtaac
    30481 cagcactaat cctaatggag caaatgattg gaagtttgta actatactac ctaagtatga
    30541 ttgaatctgt tctttctcta atagatttac tacctttaca acttcttttg tagaaggatg
    30601 tatctcttct actcctaaat tagatataat tgctgacaat attacaacaa ttatgcatag
    30661 taataaaaat atggttactg ggtctggaag tttatttcct gctctctcta taacatttag
    30721 tgccctcatt aataatccac tatctttgtt tttttcctgt gaattaattt tcctcaaact
    30781 aatcccccct cataaacttt atctccagaa atcttctatc ttaaatttta tttttttaat
    30841 ttatccatat aatttataac agactgacat agtacatttg tacctaccaa tatggaattt
    30901 ttatcagctt taaatttagg attgtgccac tgatacatac aatcttgctc tttgttgcct
    30961 actcctaacc agtaaaaaaa tcctggagct ttttccataa atatagaaaa atcttctcct
    31021 cctgtagaag gtactggatc aactatagca tcttctgaat acaaatcaca cacagactta
    31081 caggctattg tgtacatctc tttactattt ataacggctg gtaaatcaaa taaataatct
    31141 aactttgcag ttgcttgata tccacgagct atctcacaaa ctattttttc taaattttca
    31201 gatattttct ttcgtacttc attactaaag cttctacatg tacctgtcat atctactttt
    31261 tctgaaatta cattatttgc agttcctcca tttatagtac ctattgatat aacagctgat
    31321 tctaatggac ttatgtttct acttactatg gtttgaatgc ccattataat tgcacttgat
    31381 gctactatcg ggtctattgt tctgtttggt atacctccat gacctccaaa tccatttact
    31441 tctatcttaa tagtatctac tgctgccatt aacccaccta acttaacacc tatttttcca
    31501 caaggtatat ctggatgatt atgaagacca aatatagcat caacttttgg attttccatt
    31561 actcctcgtt ctactaacat ctttgcacct ttattgactt cctcggctgg ttgaaatata
    31621 aattttacat ttccatgaag actatcccta atatgagaca atacatatgc acatcctaca
    31681 aggcaagatg tgtgtatatc atgtccacat gcatgcatta taccatcata tctggattta
    31741 tactcaatat caacctcttc gcatattggc aatgcatcaa tatctcctct tagtgctact
    31801 gtgggaccat catacttccc ttttaataac ccaacaactc cggtttccat tcctaagtct
    31861 aatatttcta tgtctaaact tactaataaa tcttttatca cttttgtagt tctaaattct
    31921 ttaaaactta attcggggtg catgtgaata tctgtaaaaa aatctaaaat atcttcttta
    31981 tacttttctg aaattgaaat aagttcatgc atactaacac ctctttaaaa ttttattttt
    32041 tgattttttg ataatttaac tataaattat ataagtacta atacttataa agtttataaa
    32101 tttaatttta tttatattta tattttacta ttttatttta attaaatata ttatcatatt
    32161 ttacaatttt tttaactatt ttgacttttt aaattcgatt atataaaaag tttctttaac
    32221 taaaaattac taataagtgg ctctactcct gaccttgtgt tgatttttct ctacaggtaa
    32281 ttgctttata caccatacag actaaaatta aaagtcccat ataacctgta tatggatata
    32341 aaatgtttac tagtttacca aacggtaaaa aaccacctat acaagccaaa atagctatta
    32401 ctgttgttac taatttaaat ttagggtgtt catcttcaac aattctattg gttacagacc
    32461 ataaaagtgg aacagctgtt gtatagatgc ctaatattag tgcaactgaa aaacatacac
    32521 ctacaatagg agctatatta tctgctaaat aaagtgatgg tatttctttc atgtacaaat
    32581 ttcctatatc tgaaatcata gccaaataca taactatacc agcagtcata aacacgattc
    32641 cacccaataa acctccccaa aaagcatcct ttttactttc aatggaagct cccattcctg
    32701 ttaaaaaaac aatcattaca ataatattta atgtattata tattacaccg gaaatgattg
    32761 gactttctga tgcttttgta acttcaatgt ttttcatagc ttctccaacc atagataaac
    32821 catcaaaatg tttaaacaag cttattaatc caacagcaat tgtaaatacg gctatcactg
    32881 gtccaatacg accaagtata cttactaatt tttctaaacc catagacact gtaattaaag
    32941 tagcaacagc catcaacact cttcctaagt aaggatttat accataatat tcagttaaag
    33001 ttgaacctgc acctgaaatc attactataa gaatcccaaa taaaaatatt ggactaaacc
    33061 attcgtaaaa ttttcctaaa atcttaccac aataaaaagt gtatattctt gttggttctt
    33121 taagttttaa ttctctacct ctagttataa cttcagcacc aagaaatgaa aacaacacca
    33181 ttgatattaa tgctccaact agacccatat acccttgtga ggcaaaaaat tgtagaattt
    33241 cttgaccagt agcaaaccca gaaccaattg ctgtcgctaa ataagcacct gcaatacaga
    33301 taatattctt tatattcact ttgtctgaca tattaaatta cctccattat aaagttacct
    33361 tcctctaaga aatataaact cacagtaaat taaatgaaaa ttctgtcttt ttagaatagt
    33421 atttgattta cttttttatt ttgtatatct ttttcttttt atttatatat atttttttat
    33481 ataaataggt acagctttta taaggtttaa tattattaaa tatgtttaaa gcgctttaat
    33541 ttttattata attaaagtat acttattcag acatactcaa acaattatct atattgattt
    33601 tttatttatc aatttcaatt tttagtattc agtttataaa cttttggagt cattcctttt
    33661 tttatcttaa agtttttata aaagttattt aggctattat atccaactat ttctgcaatc
    33721 tcatttatac tttttgtagt attttcaagt aactcaatag atttttctat tcttatatga
    33781 tttagatatg atataaaagt tgtattcaaa ttacttttaa aaatcctaga tatattagat
    33841 ggattggtta aaaataatct agcacaatca tttaacttta agtcattact ataatttaga
    33901 tttatatatt ccagtatctc atttaataaa tcattattgg tatattgata tccaataatt
    33961 ttttctacag atttagtaaa ttctttcatg tccaatggtt taaggagtat atcttttaca
    34021 tttaatctca aagctttttg agcatattca aaatagtcaa aagcagttat tactacaaag
    34081 tttatttttt tagataagtg agatgttttt tctattactt ctaacccatt atatattggc
    34141 atttgaatat ctataaaaac tatgtctggc tctaaaccag tgattttatc tactgcttca
    34201 tcaccagagg ttgctttacc aacaattttt attggcatat ctttcatttc tataaaatgt
    34261 gttattattt ttagaacagc ttcttcatca tctattatta gtgctcttct catgagaata
    34321 cctccctttt agcttaagaa tataaaaaag taagatatat aaaacaacat aaaaacatct
    34381 aatatatttc ttaacattta taaaacttat taatttttca caagttctat acatactcct
    34441 tataattttc actaggaatt ttaatcatta tgtaagttcc ctcattatca ctcgacttta
    34501 tatccatatc aaaattattt ccataagcag atgtgaattt tgtatatatt aaagacaaac
    34561 catgaccatt attaatacga atacctgcct ttattttgtc tatattattt ttatctaaaa
    34621 tagttccatt attatgaatc tctataatag catactgaga atctaatctt gcaattattt
    34681 caattctctt ttctgtgtca atatctctag atccatgtgt aaatgcattc tctacaatag
    34741 gttgaataaa gttaaaaggc acagaaaggt tatataactt ctttggaata agatatttta
    34801 ctttaagtgc atctccataa cgtaatttct gtaaattcaa ataattttca atgtataata
    34861 tttcagattc taattctaca aatcttaaat cagacctcat tgtatatcta aacattcttg
    34921 ataaatctat tattgcacta tacaaatcat aactaccatc atctagtgct atgcttacca
    34981 ttgaatttaa ggtattaaat aaaaagtgat gatttattct taaattagta accatatctt
    35041 gagctacctt taaattcatt tcaagttgct ctccataatg atatgttctt gctatagtct
    35101 tctctttttc ttgtaaatcc tttcttatat cattaaatga acaaaaatta attatatttt
    35161 tagcaatttg attgagtaac cttttcatag ttctagctgc accttctggt atatcatata
    35221 aattcctatg tccaacccct aaacttgaat cagacattag aatatatcca cctcttataa
    35281 cccctatgct attattttta tatattatag aaatattata tatggttata ccatacttac
    35341 atgtaaattg attagcactt ttttgattca tgcaatcaca attttgtggg aatttcattg
    35401 gattacattt ttcaaaacaa aataaaggga aatatggatt ttttaaaact atattccagt
    35461 aatcatcata aataatcaaa ggtattttaa atgggtctat aaactgacct cgtattgatt
    35521 caactgctgc gtatagattt aaggtatttt cactataatt tactggagta ttttctattt
    35581 tattattttt attaaattca agaatctcac ttgtttcaaa attgtttaca atatttgata
    35641 ctactaactc ttttatttct ctatctcctg tatttatagt ttcatgtgtg ctaccagatt
    35701 ctatataaaa aatcatccct tgataaaatg gcttccagac cccatttata atatacaaac
    35761 cctctccctc taaaatatat atcatctgtt cttgaccata atgtacatga ttaaaatgtt
    35821 tcttaccagg catagttact gcaatgtata tattcatagc ttgttttgga ttattttcat
    35881 cataagtatg tttccattca atatatcccc actcagtatt ttgaattttc ataaaatatt
    35941 cctttcctgt aaattattta tgttcatatt ataaaaaatt agtaaacaaa aatgtgtaca
    36001 tactctttca tatgatagct tactatatca atattcatta gtttgtacac atttttatat
    36061 taattattat tttttaatta cttctatatt attgtattac ttttatatta attatttttt
    36121 atagattata gtctcacttc tatgttaatt attttttatt acttctatat tagaagtgtt
    36181 gcttaaaaat acataatttg aatcttattt aataacagaa actcccatat atggtcttaa
    36241 aacttcagga acaatcacag agccatcttc ttgttgataa ttttctaata tagctgcaac
    36301 acttcttcca atagctagcc cagaaccatt taatgtgtga gcatattcag ctttagaatc
    36361 tttatctctt ttaaatctta ttcctgccct tctagcttgg aaatcttcgc agtttgaaca
    36421 agatgaaatc tcaacatacc tattgtaact tggcatccaa acttctacat catatttaaa
    36481 agaagccgta aatcctaaat cacctgtaca tatctttact actctataag gcagattcaa
    36541 taattgtagc atagtctccg cattattagt aagcttttcc aactcattgt aagattcttc
    36601 tggtgcaact attttaacca tttctacttt attaaactga tgttgtctta ccaaacctct
    36661 tgtatctctt ccagcagaac cagcttctga cctaaaacaa ggagtataag ctgtataatt
    36721 tattggtaat tgttcaaatt taagtatttc attagcatgt atattagtca aaggaacttc
    36781 tgatgttgga atcataaaat agtccagtcc ttctatttta aacatatctt cttcaaactt
    36841 aggtaactgt cctgtaccta aaaaactatt tctatttgcc ataaatggtg gaataacttc
    36901 tgtgtatcca tttacctttg tattcgtgtc caagtaaaaa tttaataatg ctctctctaa
    36961 tctagcaccc aagcctttgt aaagagtgaa tcttgaaccg gttattttac tagctgtttc
    37021 aaaatcaagt atacctaatt ctgttccaat ttcccaatga gccttagatt caaaatcaaa
    37081 tttggtagtc tctccccaac ttcttacctc aacattatca tcatcagttt caccttgtgg
    37141 tactcctggg tgtggtacgt ttggtattct cattaataga tattccatct tgtcttctac
    37201 ttctttaaga ttttggtcta ttaccttaat tttatcagat aaatctttta gtttaatctt
    37261 ttcattttct acatctttac cttcttttat aagatttggt atatttttag atgctgtatt
    37321 taatttattt ttcataactt caacttcttg aagaatcttt cttctttcat catctaactt
    37381 aactacttca tcaaggttaa aagctttttc tccccttctt tccattgctt tttttataca
    37441 atctaaattt tctcttattc tttttatatc aagcattttt tcctcctcag tacctaagat
    37501 tggatttttt ctcttaatct caaataactt agataatatg ttttatgctt gaggttaaga
    37561 aacctttttt tatccgaacc tattattttt atttatattt tactcacttt tttatctatt
    37621 gtcaaattat atttaattaa ataaatacaa tttaatttca agagaatatt tctagattta
    37681 acttcattat aattatatcg atttttctaa tcaattatct attttgactt tttctttatc
    37741 aatcttgtat agttattaac tttcatataa gtttttttat attataatat agacctatat
    37801 atctcttatt tggatagtat tattttaata aatgatttaa gtataggtat gaaattaaat
    37861 tttttagaac tgattataag aaatactcaa agaaaagtag taatttcccc agattcacaa
    37921 tatgttttat atgaaatgtt gtaaggtaat ctatttaatg aatttaaatt tgctattata
    37981 aacttagctc caaaatctac tgcaaagtaa tatacatatt cgttttatac taataactgc
    38041 aactaataat tacttaattg tttaatgtat tttaaatagc tttaataaat tgatagttct
    38101 ttaaaaaggt agaatcaata aaattatact ggtaaatctt caatacaata attaaaattt
    38161 aataataaat ataattgttg atttaactgc aatcttattt aattctacct aacttattat
    38221 ataaaactac tttttataga ttataaaata tctaacttgc atctacttca aagaatacaa
    38281 tacttctcct tctcttatag tctgcaatac tttaatatct tttattttca tagggtcgat
    38341 tgtaagaggg ttttcatcta atattatcaa attagccaat ttgccttctt taattgagcc
    38401 ttttttatct tcttcaaaat attgatatgc tgcatttata gtaacaccct ttaaggcatc
    38461 taatgggctt atcttttcat tttctcctat ttgtacacct ttttttgtaa ttctattgac
    38521 agcacaccat actgtttcca gcatattagg tgctattact ggtgtatcct gatgaagagt
    38581 gtagattaac cccttttcta tagttgtttt aagtgggcta atcttaaatg ctctatcttc
    38641 tccaaggttt ttgatatgaa tgtcacccca ataatatgtg tgagctacaa agtatgaagg
    38701 tatcatattt attctcttca tatcatcaat ttggtcttct cttactgttt gagcatgtat
    38761 cataactggt ctcatattat tactactttg ctcttttaag gttaaaactt tctcaaatac
    38821 atctatcaac tgctctgctg ctgcatctcc attacaatga gttaagagtt gcatcttttc
    38881 ttttagtgaa atatctataa acttttctac ttcttcatct ttgtatatag ggtacccaca
    38941 ataaccatca tctgaatttt catacggttt actcaaccat gctgtcttac cttgtggaga
    39001 accatctaag aatatcttat agcctcctat tttaaatctg tttatatatt tttttataaa
    39061 ctctctattg ttatctgcta caggcttact ttttttcaaa tttacatatc ctacaacatc
    39121 aatttttaat ttattttgat ttgccattgc ttttaaaaga ttaaattgat tttcttccat
    39181 tagaccttct tgagctgttg taataccata gcttagatat atgtcctgtg ctttttcaat
    39241 tgaattaaaa atctcatttg atgatggtgg ttttatttta gatgatacat taaaaaatgc
    39301 attttcttct aagtatccat ttggttcttc actgccttct actctaccta tatgtccacc
    39361 ttctgggtca tatgtttcat tagtaacacc aagctgtttt aaccccaatg tatttgcaac
    39421 tcccatatga ccagaagcat gcgaaattag tattggattt tctgaagacg cactgtcgag
    39481 tacattctta tctggatgtt tattttcttc taaaaaatta ttatcatatg aaaatccaat
    39541 tatccagtct ccttttttta tattatttga ctctttgaaa tcctgtattt tttttactat
    39601 gtctttaaaa ctagttgcat cttctaaagg aactaacttt agagtagtag caaaagctat
    39661 caaatggcta tgtgagtcta taaaagatgg catcaatgtc ttaccttgca aatctataat
    39721 ttctgtatct ttatttttca aagcaaatac ttcttctttt gttcctatct tttttattat
    39781 cttatctttt ataagaatcg catctccaca tattgaatct tccattgtga tgatatttcc
    39841 attgtaataa attttttctt tcataaaatt ctccttatgt tgtctacttt aataaatttt
    39901 tttctttatt ttctacttaa ttatattatc ttctttataa actttttctt tagattttaa
    39961 ttatataaaa gttttatttt taattattgt ttgccaagaa gtaaatacta ttcattgtaa
    40021 ataagacaaa ttaataggct ttatactaat tgaaaaaata ttataagtta ttaaatttaa
    40081 atatctaaac tcaattatat atgtacaatt gtaatttttt aaatcatgat gtattatttt
    40141 aaatatacag ttatattatt attcacaata taaatatctt cgttctcaaa taacatctca
    40201 tgtagtctat tcaatgcaac aaatttaaat attttttagg aggtttttta tgaacaagga
    40261 aaataaaaat gtaagaattg ctgttgtcca ggcatcacca gtcataatgg atttagaaaa
    40321 aactgttgaa aaagcattgg gattaattaa agaagctggt agaaaagggg caaatatcgt
    40381 agttttccct gaggcattca tacctgcata tccaagaggt ctttcatttg gatttgttgt
    40441 tggaagtaga acaatgaaag gtagagagga ttggaaaaga tactatgata attctgtacc
    40501 agttcctagt gctacaacag atttattagg aaaagcagca caagaagcag gagtatatct
    40561 atcaataggt ataacagaga gggatggtaa tgatataaat tgtacccttt attgcacaaa
    40621 cttatttttc tctccagaag gtaagctaat tggtaaacac agaaaactta aacctacagg
    40681 aacagaaaga tgtatatggg gagaaggaga tggaagtact cttacagtag ttgatactcc
    40741 atatggaaaa atgggttcat tgatttgttg ggaaaattat atgccattag ctagaacagc
    40801 tctttatgct aagggtgtaa aactttatat agcccctact gcagattcaa gagaagagtg
    40861 gcaagcaact atgaaacata ttgctttaga gggaagatgt tttgtaattg gatgtaatca
    40921 atatgtagaa aaaaacatgt atcctactga ccttaattac tataaagaac tagatgcaga
    40981 accagaaatt atgtgtccag gagggagttg tatagttgac ccttttggaa aatatgtagc
    41041 tggccctatt ttcaataaag aagaaatgct aatagctgat ttagacctag aaaaaatagt
    41101 tcttagcaga ctagattttg attcagaagg gcactattca agaccagatg tatttgaatt
    41161 aatcgttcat gaataacctg tttacacaaa cttctacata aaattttttt acataaaaaa
    41221 atgagatact cataagtaaa ttacaagtat ctcatttttg cttaaaaccc aaaatcctaa
    41281 ttgcaaactt agtcacctat attttttcta aatcaactac tgttcttccc acatgtgttc
    41341 ctgccattat tgaatctata ctgtcattta attcttctaa tgataccaca tttaccatat
    41401 cgtctaaatc atctaatttc cattcatttg ataataaatc ccatattttt aatcttaaat
    41461 tcattgggca gtccacagaa tctataccat acaaggtaat tccctttaag ataaatggat
    41521 atactgaact tgtaaaatca actcctcctg cattaccaca agttgttact gctccacaat
    41581 aattagttgt ctttattgct gttgctaagg tatttcctcc tactgtatct attactccag
    41641 cccatcttgg tctaagtaga ggtcttcctg agttatcatc cacttctgac ctatgtataa
    41701 catctttaac acctaagttt agtaatgctt gtttttgttc ttctagtttt cctgttgaaa
    41761 ctacaactga ataacctaat ttaatcaata ttttggttgc aattacagca actcctccag
    41821 taccaccagt tactaataca tctcccatgt ccttgtctac agaatctata aatttgtaca
    41881 cagataaagc tgctgtaaac cctgctgtgc cataatccat tgcttctttt agtgaaagat
    41941 ttttaggaag tctaactacc caactggaag gaactcttat atattctgaa aatccaccag
    42001 aagtattcat tcccaagtca taacctgtta ctaaaacttc ttctccaatt ttaaaatcat
    42061 cacaactact agattctact ataccagatg catcaattcc tggtgtatga gggtattttc
    42121 tagtaacacc cttattacca ttggcagaaa gtgcatcctt gtaatttaga gaagaatatt
    42181 tcacttttat taaaacttct ccctctggca atgtatctac atctctttca actatatttc
    42241 ttttaaaatt tccttcctct tctgtaatat atagtgattt aaatttttta ttcataaatt
    42301 tcctcccaat acatttagtt ttatgttaaa ctaattatag tttataaata gttttatgtc
    42361 aaactaattt aaatagatta aagattggag aataatttat ggaagataaa tatatagtac
    42421 atttcataag taaaacaaag actaatatga ttaaatttat tgaaaataaa ctcagtaaaa
    42481 atgatttaga tgagttgata cctactcatg gaaatatctt aactgcactt tatgaaaata
    42541 atggaatact tacaatgaaa gaaattgcaa ctaaaatagg aaaggacaaa tccactgtta
    42601 cagtgttggt taataaactc ataaatctag gatatctaga aagacaaaaa tgtaccaatg
    42661 acaaacgtat cacatatata aagcttacaa aaaaagcact actcatagaa gatacattta
    42721 atagtatctc aacacaagtt aaagaaacag cataccataa tattacagaa aatgaaaaac
    42781 aagaatttct tagaatttta aaaaaaatta atgataattt taaaaatgct gactaaatta
    42841 agcataatta tatcttctat tggaataata aataaaaaga atcaaatatt gtaaaaattt
    42901 attgtgatag agaggtagaa tatgaattta aaagatagta aaactaaaga aaacttattg
    42961 agagcttttg caggtgagag tcaagctaga aatagataca atatttctgc atctgtagca
    43021 aaaaaagaag gattatatat aatagaatct ttatttaatt acactgctga ccaagaaaaa
    43081 tcacatgcaa aacaattctt ttctaaacta aaagaatttg ctggtgaaaa cataaatata
    43141 tcaggggcat accctgtaga tttatatgat aaaacagcac aacatcttaa agctgcacaa
    43201 cataatgagc ttcaagaatg ggatgatgta tataaaaact ttggaaaaac agcacgtgaa
    43261 gaaggatttg aatctatagc taagttattt gaaaatatag ctgaaataga aaaagttcat
    43321 ggtgatagat ttggtagata tgctactgat ttagaagaag gtactttatt cagaagaaat
    43381 gaagatatac aatggatatg tacacattgt gggcatatac atgtaggtaa agaagctcca
    43441 aaagcttgtc ctgtatgtct tcatccacaa ggatatttct tagattttaa aaactcatta
    43501 tttgaataaa ctaagataat cattttattt aaacaatttg ctatatttat attaagtatt
    43561 tttataaata ctgtattatc ttaataaaaa taaaatgaac cattgatatt actataagta
    43621 gaaaatgtag tttaaataca atttatagta cttcatcatg gttcatttta ttgtttacta
    43681 atccctatag attgcttaaa tctatcttta agttttacat attcacataa aaactcatct
    43741 ttaaacccaa tatttaaata aagtgtattt taggtagatt attgtaatac attatataag
    43801 ataatacaca ctacgataac tttatactta tatcatttat ttcttttgtt aagtcaatct
    43861 caataatctt aactacatct ttttcaaatt ttactttttt ataatccaga catccaacta
    43921 caaatggaac tccaaacttt ctaaacaaat aaatctttcc attttcatta tatattgatg
    43981 taaaattttc ttctattata ttcactatca attttaactc ttcaaaagtt attgtagatt
    44041 taactaaaaa cttctctatt atactcaata taagaagttc ttttttacct atactttgct
    44101 ctttcttata taaattttga aatatttctt tggtgtaatt acatataact tctttactaa
    44161 gaataaaatc aatatcaaat tctttattaa tatctttttt cataaacata tttgcaatgt
    44221 catcaagaga agtctcttct ttcatagaca atattaactc tattctttct agtattttat
    44281 ctcttggaaa gaaagtctct tgacctgtaa aagcagattt ctttataaac cattcttctg
    44341 gtattatgtt ttttcttttc catctatata attgcccata agatatatta gttttgctca
    44401 ataaatcttt cttagatatt aattcttcca taactcttct agcccacctt tatactgttt
    44461 tttacagtag aattatctga aactgacaaa ttatcactgt attcaatatt tccaacatca
    44521 caattatcta ctaaaaatat gcttttacct cgtatatctt ttattgatgc atcttctaat
    44581 tcaatagtat ctccctctat caagttgcat ttaaactttc ctgaaaaaat attaataatt
    44641 ttaattaatg aaaaaacatc tttgcttctt cctattttta tattagtcgc acctatctct
    44701 ttacaataag aacctcctcc tgaataaaca tatatatttt ctccatttaa aaggccatca
    44761 cattctatta ctccatatac ctttatatct tcacattcta tatttgattt atttctcatt
    44821 tcgccataga tttttatatc ttgtgcatac atattttcac ttacacttaa ttgtcctctt
    44881 attgtaacat tattacattt aagtttgcca tccactttct gttgagcagt tataactaag
    44941 tcatctattt cagcatctcc atatatgcta agttgcccat tcactcttac acgctctgct
    45001 ttaagattgc ctcttataat agtttttcca ttaacaacaa aattttttat attgatgtca
    45061 ccttcaaatt ttgcatctcc aaggactttt acttcatcac ttttgatatt tccttttgat
    45121 ttagcacttc ccacgattct tatactttca tactcaccac tacttataaa gccttctcca
    45181 agtattttta tagacccttt ttccatatta ttacctcatt ttaaatttta tttttaaacc
    45241 tacttattac ttatccttct ttaattttac tttttcattt atattcttta tttcaccaac
    45301 tattgaatct tcatcaatct ctataatttc actatactcc aagctttcta cataacatcc
    45361 cttacctatt ttaacatttt ttcctcttac aactttgact tcactatttt ctaggcttat
    45421 ttcatctgct tctataatat ttgcaaataa tttgctttct atatactttc taattgataa
    45481 taaacccaaa cttattaaat ttgaagatac cttttcaaag ttgatatgct ttttttctag
    45541 catacgaaat tttttgcaat aatctccatg accttttttt atatttatac tacttgctcc
    45601 aacttcatta aaattagaaa ttccatttaa actaatatta acctcttcac aattcaaaaa
    45661 tccattacat tccatgattc cacttaaatt gatattttca caatctatat tctcatttgc
    45721 ttttaaatat ccttctccac gaataatatc cgactttata cttccttcta cattaataat
    45781 tccactagtg tcaatttcaa cagaattaat atctcctgta catctaagaa gccccgatat
    45841 ctcaactttt gatgccagta tatttccttc tactttactt aaaccagatg taaaaaattc
    45901 attacattct gttgtaccaa acacttttgc tgaaccagaa gaattaaatt tactacattt
    45961 tacacttcct tctatttttc ctgttcctgc tatattaaca ttatcaaaaa ttccaccttt
    46021 acattttcca acgccatcaa atcttagtga acttaattct tcattcataa tgatatcctt
    46081 tctttaccgt attttatctc taagcttaat ataacaaaac attgttacgt tgtcaagtat
    46141 gataataata cttaataaaa taaccataat ttattttata taaataaaca caaaaaataa
    46201 taggaaaaat actttatcta aactataaat ctaatttctt agattgtggt ttaagtaaaa
    46261 tatatcccta ttactcaatc tttatatatt cattttataa acatctaaaa tataagtctt
    46321 taaattctat agtaacctac aagccactat cttcttctat ctattgataa atctttctat
    46381 tacatctgct agtctctcca tatcagttgg ataaacttca cctatgctac ctattctaaa
    46441 tgtatctata tcagtcaatt tacctggata gataacaaat ccattagctt ttaaataagt
    46501 ataaaattcc ataaattcaa actttgcatt tttaggatat aagaaagttg ttattacagg
    46561 tgattgagca ttatcattca ctaaagtatc aaaacctaaa gattttaatc ttgaagctat
    46621 tgtaaattga ttttctttat atctagcata tcttttttca acagaacctt cttcttctaa
    46681 ttctaataaa gcttgataaa aagctcttac aacatgtgta ggtgaagtaa atctccattt
    46741 accattattt ttctccatag tctcccattg cgcatataca tcaagagata atgatttagc
    46801 tataccttta catttagata attcttcttt attagctatt ataaaaccaa atccaggtac
    46861 tccttgtata catttgttag aactactaac taaaaaatct atattaaaat cttcaacatc
    46921 aatctcaatt cccccaaaac tactcatagc atcaactata taaactttgt tatattcttt
    46981 tgcaagtttc cctacctctt gtatggggtt taatctccct gtagtagttt cacagtgaac
    47041 cattgatata tgtgttatat ctttattttc ttttaataaa ttttctacta catttaaatc
    47101 caccgcttct acatctttaa atgtgcaatc aacaaattct atgttaagat aattacatat
    47161 atctttcatt ctctttccat atgctccatt tgcaattaca agaagtttac cattctctgg
    47221 aatagtacta cctattgtag cttcaactga aaaagtacca cttccttgca ttaatacact
    47281 tgtgtatttg tctgtattct ttgttcctaa agaaattaat cttcttctaa catcttgtac
    47341 taagtcatta tattcaacat cccaagtaca ccaatctttt aacatagatg ctcttaccga
    47401 tttagtagta gatagtggcc ctggtgtaag taatatgtaa tcattttctg gtacaaagtc
    47461 tgatttaata gttttatttt ctatctttac caatacatct tctaattcag ccatagtttc
    47521 tattacaaaa tgtgcacctg cttctttaaa tttctttgaa actgtattca ttttaatttt
    47581 taattcttcc ttatccatgt tctctacttc ttcttctgta agccctaact cacttgaacc
    47641 ctttattaca gcaacactcc acattcctgc atttacgcct tcttttacgt cacttattgt
    47701 atctcctact tttaccatag aactcatagg agatactcct aaagcttcag catttttata
    47761 gcacatccaa ggatatggtc ttccttgtga tacttctgat ggtgttacaa gaaaatctgg
    47821 tgagtatcct ttttttgcag cgtttggttg aactatatcc atcatctctc ttgtataacc
    47881 tgttgtagag cctattttta atccattttc tcttaatttt tcaatagttt caataacatg
    47941 ggggattgga gtagtatact cttctaatgt ctcaaataac attggctcaa attcagcata
    48001 aagttcattt acgtcgtctt caattggcac tttaccaaac ttatctgacc aaagattttt
    48061 tattctatcc atttcacaca tttctcttat atggtctatt tttaattttc ccataggttt
    48121 tcttgcttct tccattgtta catctatgcc tcttctttta aatatctcta taaatacatt
    48181 aagaggtgca aaacatccat aatctactgt tgttccagcc caatcgaata ctactgcttt
    48241 tattttttct ccatatatct ttttcatatt tatagcctcc atagattctt tttagaattt
    48301 ttgtgttttt aattgttttt acttttaaag tataactttc atatgttaat tatacatcat
    48361 atttaagtta aatatatatt aaatttctgt ttttagttgt ttttatttgt tttaagttgt
    48421 ttttattcta tgtcatattt ctataaaatt ctaaatttac aatctaaaat ttactttcta
    48481 atattaatct ataaactgac tatattttat gaatttggtt gtattaagca tagttgtatt
    48541 ctataaaact aagggtttat tttgcttcta tccatgttat atttatctca tttaacttat
    48601 ccttccattc attcggaggc tctacatcac aaataacaaa atctaattcc tctaaatctg
    48661 ctatcttata cagactagca attccgattt tagaactatc acacaataca aaactttcct
    48721 ttgaattttt tatatattct tttgacaaca atgccttatt ttggtctata ctactaattc
    48781 caaaactatc aagtatacct tcgctagata taaaagcttt atctacgtat aagttcttca
    48841 tagtatctat tgacattgga cacgctgttc tttgatgttt taaatttacc tttccaccaa
    48901 taaatataac ttccccatca aataagcctt gattttcata agaaatcaat tttgatagaa
    48961 ctggataaga atttgtaata atttttaaat tgtttacaga tattatataa tctacaattt
    49021 gcaaattggt agtaccttca tctatgatga ttgactcatt gtcattcaca aacttagatg
    49081 catatttagc aatactttgt tttttatcta aattagtact atttctcttt atatgttctg
    49141 gttcaatcac cccataattt atttttatag caccaccata tacctttttt aatttatttt
    49201 cattttctaa ttcttccaaa tatcttctta ttgtttctga tgatacttct agtcttttta
    49261 ctaactcttt agtatttacc ttaccttttg aatctaataa tttcagtatt tctttttttc
    49321 tatctattga atttaaagac attcattttc ctcctaaata taatatattt ttctcctata
    49381 atattacaat gatacctaag atttacaaaa tcatatttat atattaaatt ttttacttaa
    49441 ttaaagttgt cttcaaaaga ctatgtatta tcattaaaaa agtccatcaa atattagtat
    49501 cagatggact ttgtaaaatt ttattttata aattaatatt taatctaact actaatttat
    49561 tttcttgttt ccaagaattt tactaaatta tttacagtag acatatcttt tctctctaaa
    49621 tcagttggtt gaagctctat tcctaatcta ttttcaattt caagtaaaac ttcaattata
    49681 gctaatgagt ctaaaagctc tgtctcaaat aagttaaggt ctaaatcttc tcttatctca
    49741 tcagtcccta atacatcttc aaatatttct ataactgtct cttgcataat ttttcctcct
    49801 taaagttaag ctaaataacc tgagaatatc agtaatccaa aacatacaat gtggaatgta
    49861 atgaaaatct gtactctctc aaaccatttt tcttttttat gttttttata aaatttggat
    49921 tttctctgat atatatcagt tagaacaagt gccaaacctt gatatacacc ataagcaacg
    49981 tagtaccaag ttagcccatg ccaaaatccc attgttatca tagttatcat ctgagccaca
    50041 tgagcagcag tagttctttt cttaaatctc ttctttctca ttgatgacat aacaaatcta
    50101 gaaaaaatat aatctccaaa ccatcttgaa aggcttatat gccatcttgt ccagaactct
    50161 ttcatatctt tactgataaa tggcttgtca aagtttatag gtacttgtat tccaaatatg
    50221 taacctgtac ctatagcaaa taaactatat cctgcaaaat caaagaatag atacaagcta
    50281 tatgcgtaca tataacttaa aatatttata aaactcatat ctttaggtat tattgatacc
    50341 caatatgtat ttatcaaaaa tgctataaca aacttataac ctactcccat gacaatattt
    50401 tttattcctg gcagtaaata ttcttctata tactcttttc tagaaatttg tttttccaag
    50461 tcttgttcaa atcttcttga cctatcaata ggtccagaac ttaaagttgg aaaaaataac
    50521 ataaaataaa gcatctttga aattttaact tcttttatag caccatcata aatttcaata
    50581 accatctgta tagctctgaa atttaagtat gatattccaa taaatccaat cattccaaaa
    50641 gaagtaactg gagatatttt attgattatg attggaagca ttgatataaa caaaaagctc
    50701 caatatacgt atttattttt agtttttctt cttacatatt catatccttt aactattatt
    50761 acttcaagaa taataaatat tactaagtac tttagttgga catcaattcc tactattagg
    50821 aatatcataa acaaacttgc caacatacca taatacttta tattcttacc cattagacct
    50881 aaaattactg ctggtattga tgttaataat aatatataaa gataaaaata atctccatac
    50941 tgtgaaaaaa tcattaaatt tcctccataa gtttctttct gtctatttta ccgttgatat
    51001 ttgttggaaa ttcagagatt attgaaatat ttcttggaat catatatgaa ggtatatact
    51061 ttccaagttc cttttttatt atcatcccat ttttaatatt acttaaatca ttcttttcat
    51121 ttaactcaac aatacctttt aagtaagcaa ttttttcgtc cttatatact ggtaaaacca
    51181 ctacattttt tacattatgt acttttctca aattattttc tatatcttct atttcaattc
    51241 taaatccatt taatttaatc tgaaaatctt ttcttccaca ataatatata tttccatcta
    51301 aaagatatcc catatctcca gttttataag ctctccactt tataccatct atttcatcat
    51361 agaaaaatac ttcatcagtc ttttctttat tattgaagta acctttagaa actgatggtc
    51421 caattattat aatctcaccc ttttcatttt ctttaagttc atttccagct tcatcaagta
    51481 tttttatttt acaatttgac ataggatatc caactggaag acttttttca tcctctatag
    51541 ctttttgagt catatcattt acgctcacac caacagtagc ctctgttggt ccatatccat
    51601 tgataactct tgtgtttgga aatctgctca taagttcttt agtaagattt tttgaaagtg
    51661 cttctcctat gaatatcatt gattcaagct taggaagcat tttactattg aactcttttt
    51721 cagttataca tacccctgca aaagaaggag ttgacaccca tacagctata tctgatatac
    51781 taaattgtct aaatagttct ttatagtctg ccaatacatc ttttgatatt gaaaataatg
    51841 tagctccatg gataagacca ggatatattg ttgtaactga aaggtcaaaa gaatatgctg
    51901 gttgattcat tattactttt tcacttccat ctatgtttag atatgggctt atccaatccg
    51961 aaaagctatc caaattgttt gaacttattt gaaccccttt tggttttcct gtacttcctg
    52021 aggtaaataa tatatatgca ttttcatcat cttttaccca gttttcttta tctagtgatt
    52081 ttccctgata ttcatttatt atatccttta gtttatccat atcaattaca ttaatatctc
    52141 caaaatcttt ttcatcacta aaattaaata atacttttgg ttttatctct ttagtgactt
    52201 caaaaactct atcaattgga aaactaatat caagaggcac atacgctctc cctgatttta
    52261 aagctcctat catacatgcc attatcatat tttctttatt tccataaatt actataggag
    52321 tatcttcttc tttgtataca tcttttaaaa atattgatat agcatctgaa tactcattta
    52381 aatctttata agaaagttta tctccattac atattagtgc tattctatct gtatttgaat
    52441 atttctttat tccttcaata attttcatat aagaatgctc ctttaaaatc cgttataaat
    52501 aaatggcaat tctttaaatg gagtaaatgt tagaactcct atcgccaata ttataaccat
    52561 agttaaacaa atactagtta acaaatcctt attgttcttt aaatatttta aataatctct
    52621 cacagacatc tacccatcct ttcgtgccaa gatgcattac atcccttaaa taatacttat
    52681 ctgacccttt atctttaaga tttagaacct caaagccttt gctttctgct atgttttgtg
    52741 ctttatcgta gtattgattt ctttcttttt cagaaatacc agtcaaatta tagaatttat
    52801 ccatacttgg gattaataca acaactggct taatacctaa gtcagtacaa acatttagca
    52861 taagtttata actttcaaac tccttagatg ttaataaatt tacatctttg tctcttcctt
    52921 tgtattgatc tataccatct ttaaaatgct gtttataata ataattatca atatttagtg
    52981 gatttttacc aactcttttt ttagcatctt caatggcttt ctttctctca tgcgaccaat
    53041 ttattgggct ttttcttttt gttgctctct ttttatctag cttaattaat cgtttataaa
    53101 gaataccctt ttctttaaga gctatacagt actttcttcc ttgaaaataa ggctctaaaa
    53161 gcaccttttc agctttttca agcaacgtct taggctcata tagcttagca tataatgctt
    53221 ctgctttata ctcgtcactt ccccataata acttacttga tttttttgca tactcaatct
    53281 tattttgttt agatattttt ggattatcta aaaatcgata aaattgtatt ggtgaaaatc
    53341 tagactgata atggtgactt gtgactccat ctttttccat aaaccattgc atagaaatta
    53401 acaagacaac tttcttatta tcaatattag gattcatact tcctaatatt gcagcatctt
    53461 gtaatgtctg agtatatgct ctcccaattg caaacacctt atttttactc ctattcgtat
    53521 taaaatagta ctttggatgt tgttttgttg aattactaag ttctgatgac cccaaaatca
    53581 taatatcttt ttctcttaaa aaatgattat ttgctgtaac tcctttatct tttatatcac
    53641 ttaaagtatc atccataatt ggaagtagat ttttctccct caaaagttca tcagttttag
    53701 aatcaagaaa tttgtctagt ccaaataaaa atactacgcc tattataaaa ggtgtaataa
    53761 agtatatcaa ttttctcata ttttctctcc tctaaaaata ttcaaattta tgttattatt
    53821 aatcatatta gttttgatat gtatattcaa ctacaaaatt gtaataaaat cgtcaaaact
    53881 ttttttgata ctgttacaaa attgtaaaaa aaagaaaaaa agcgccaaaa ataaatttct
    53941 ttttagcact ttttcatact tataatttga cattttaaca cttaactaag tatacatctt
    54001 accttaactt aaaattaaat ttatttaaga atatatatta taaattctta tatactttat
    54061 aatataaact atatactatc agctggataa acaatactac tttgtcttct tatctcatcc
    54121 ataatttcca ttactattat tgagttttca taagaattta tatttgattc tattttattg
    54181 ttatttataa gacttataaa ctctacaagt tcataataca ttccttctat ttctctaggt
    54241 ttttcctctg ctttttcttt tggaatagat atatcttctt ctcttccatc tctgtattta
    54301 ataatagctt tttcaaatag attaagcttt tcaattatta tacttccctc ttctccttgt
    54361 atttcagatg gtatataaga atcagctact ttagaatact gaattatagc atccatatca
    54421 tcatattgaa atacagctga accttctccg tccactccag tttgaagtac atgagaaaca
    54481 gcctttacag atttgggagc cccaaataaa tttaccatag gatgtataca atacactcct
    54541 atatccatta aagctccatt tgataactct tttttaaatg cattctctat aattccattt
    54601 ttatatttat catatctgga agaatactga caatagcttc caaaaaatct tcttattttc
    54661 cctattttat acaagttttc tttaactgct ctaaagtttg gaacacatgt aattctcata
    54721 gcttccataa gcaatacatt attatctttg gctgttttta tcattaattt gacttctttt
    54781 aaattagatg ctaacgattt ttcacaaagt acatgttttt tgtgttttaa acaaataatg
    54841 gcttgccttg aatgtaatgc atttggagaa gctatatata cagcatctat atccttcgat
    54901 ttagccattt gttctaaatc atcaaaaaaa atacttgctc catgtgacat tccaaattct
    54961 ctagcttttt ctaaatttct agaatatata gcaaccaatt caaagtcttt aaccttagat
    55021 gcagctttta gaaatatatt tgctatattg cttgtcccaa caataccaaa tcttacttta
    55081 cccatcataa atcactcccc attttctaca ctttatttta attttaatag aaaactttac
    55141 aacttatagc tatattataa aataatttta tcaaataaaa aagaaagcta attttaaatg
    55201 atttcaccat tttaacatag ctttctttta actacaatct aaattcaact tatattttta
    55261 aagttatctt tctactatat ctttatttcc cctcaaaaat tttatagtaa gaacttcatc
    55321 cacaaacaaa gttgctaaaa gtataattac aagaattggc caataaggta ttataagact
    55381 atataaacta tcaactatat atacttgaaa atacctaact ccaataaagg tcaatatagt
    55441 ccaatatata gagaacttta gacatactat tcctctacta ttgtacttat aatctgaata
    55501 atcccaatag accttattaa aatatacttt cataagtatt cctgtaatat attctactac
    55561 tgttggcact actagacata ataaaagcaa tgtaaatata ttatttgggt caataaatct
    55621 tgatacctct attataatcg acattgcaat tgcatacatt ggtttaaatg gaccatttaa
    55681 aaatccatct tcttgaaaat gtccttcttt ataataacta tataaatttt caattatcca
    55741 acctataaaa ccatacaaga aaaaattaaa taaaaaatat aatagagaac ctacattatc
    55801 catgaatatt cctcctagct gtttatactt attttttctc atattcatgg atttattcta
    55861 aatcaaagaa attatattta atttatttaa ttaatatttt atattataga ttgtgacatt
    55921 ctttagagct caaacttttt aagtattctc taacttctaa taaattttca agtatcttat
    55981 gtgattgtga tttaatttgc tcatctggct cttttaaatc tggtacattt atacatctta
    56041 taccaccatt gtatgcagct tcaactccca taggcgaatc ctctatcaca atacaatttt
    56101 ggggattaac atttatcttt ttagctgctt ttaagaatat ctcaggattt ggtttagagt
    56161 ttacaacatc atccccacaa actatagcat caaagtaatc ttttaaattt gccttagcta
    56221 atctctttac tgctctttct ctctttgttg atgttgcaac agccattttg tatccatttt
    56281 cctttaaaaa agagattagt tcattgactc ctaatttgat aggagctccc tccctatcca
    56341 taaattcaat catattttta gttttttcat catacaaatc tattattggt acagaactat
    56401 cgtatatatt tgtgagacct tctattatac ctttacgatt tcttcccata actgatgtat
    56461 agatttcctt agtcatagta tatccatact tttcaaacgt ctctatccaa aattcaagag
    56521 aaattctctc tgagtcaaat aaaactccat ccatgtcaaa aataattcct tctacttttt
    56581 gcatacaatt cctccaatat tttttgatat aattatatta cactttttat gattaatttt
    56641 acaaccctca atttatccaa ctctaatatt gtgaaattgt aattttcaaa agttacactt
    56701 tgatttactt taatatttga accaagcata tatgatatcc acccacctat actgtcaaat
    56761 ccatcatgct ctatgtcaag tccaaaatac ttattaatat agttaatgga ttcagttcca
    56821 tcaactaagt aagaacctgc tcctattttc ttaatatgag tctcttcttt gtcaaattca
    56881 tcttgaattt ctccaactat ctcttctagt atatcttcta tcgttaccac accagatgta
    56941 ccaccatatt cgtccacaac tatagcaagt tgaagttttt cctttcttat cctctcaaga
    57001 gctttatcta tagtcaaatt ttcagaaata tatataatat ctctcaatat ctcttctagt
    57061 tcaattttat tttcatttat cttttgattg tataaatctc ttatatgtac aaaacctaat
    57121 atatcatctt tgttttttct acatactgga tatcttgtaa caccttcttc ttttaaaata
    57181 gctaatatct tttcttcaga gtcactttca tatatacata ccatatcggt tctaggaacc
    57241 attatctctc taattttctt ttcctcaaat tcaaaaatat tatcaactaa tctttgctct
    57301 gattcatcta taagcccact tttataactt tcttccacta gtattcttat ttcatcacct
    57361 gtatgtggtt catcaacttc atcagcttgt gaatatccaa atggtttaag aaataaatca
    57421 gtacttaagt tgaaaaaata tattattgga tatgttaact tataaaatcc tactactaaa
    57481 aaagatgtac tcaacattat tttttctgta ttataaagtg ctaaagcttt aggaaccaat
    57541 tctcctatta caacctccat cattgttata attaaaaaag aaatggaaat tgatatagta
    57601 tatacaatac tttcactaag attaaatatg cttattattg gtaaaatcaa ctctttaact
    57661 gtagattccc ccatccaacc taatgcaagt gaacaaagtg ttataccaag ttgacatgca
    57721 gaaagatagg aatttaagtt gtcttttatt attttacatc tttttgcatt attattacct
    57781 tcagttatca tggtgtcaat cctagaacta cgaagtttta ccatagcaaa ttcacaagct
    57841 acaaaaaaag catttatcaa aacaagtatt attataagtg ttacatttaa taactcccgc
    57901 ataaagtatt ggttcttata gtgtaagaaa tctataagaa ctcaaagttc cccccttata
    57961 tttataaatt taatttataa tatatattct atcatattta ttaatatatc ctactttatt
    58021 acaaataatt tttataaact aaagaacccc tttaatattt atgattgtct atttgataaa
    58081 tattaaaggg gttctttagt tatcattttt tatttctaaa aaatcttttc ttaaatgatt
    58141 tagttatcta tgcatccatt ttttttacat aatttaatga ttaaaaatat taatttttta
    58201 tt
//
LOCUS       DBGJFK010000015        57789 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.015, whole genome shotgun sequence.
ACCESSION   DBGJFK010000015 DBGJFK010000000
VERSION     DBGJFK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57789
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.015"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            251..886
                     /locus_tag="ACOIAP_001171"
     CDS             251..886
                     /locus_tag="ACOIAP_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGZ2638074.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            1070..1639
                     /locus_tag="ACOIAP_001172"
     CDS             1070..1639
                     /locus_tag="ACOIAP_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGZ2638075.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            1717..1854
                     /locus_tag="ACOIAP_001173"
     CDS             1717..1854
                     /locus_tag="ACOIAP_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638076.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            1851..3626
                     /locus_tag="ACOIAP_001174"
     CDS             1851..3626
                     /locus_tag="ACOIAP_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2638077.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKDLFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDNITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLKERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVRSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            4050..5357
                     /locus_tag="ACOIAP_001175"
     CDS             4050..5357
                     /locus_tag="ACOIAP_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HGZ2638078.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDSAEKVESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            5686..6225
                     /gene="hpt"
                     /locus_tag="ACOIAP_001176"
     CDS             5686..6225
                     /gene="hpt"
                     /locus_tag="ACOIAP_001176"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGZ2638079.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLKELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            6582..8267
                     /gene="bclA2"
                     /locus_tag="ACOIAP_001177"
     CDS             6582..8267
                     /gene="bclA2"
                     /locus_tag="ACOIAP_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HGZ2638080.1"
                     /translation="MSDISGPNLYQDVGPTGPTGPTGATGPTGPTGPRGATGATGANG
                     ITGPTGNTGATGANGITGPTGNMGATGPNGATGSTGPTGATGATGANGITGPTGNTGA
                     TGANGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLT
                     GATGATGANGITGPTGNTGATGANGVTGSTGPTGSTGATGPTGAVGATGANGVTGATG
                     PIGATGPTGADGEVGPTGAVGATGPDGVIGPTGPTGATGATGANGLVGPTGPTGATGA
                     NGLVGPTGPTGATGVAGAIGPTGTVGATGPTGADGAVGPTGATGATGANGATGPTGAV
                     GATGATGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGPIG
                     PTGPTGANGVTGATGNTGATGANGATGPTGATGATGVLAANNAQFTVSSSSLGNNTLV
                     TFNSSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNF
                     IAKAVNTLTSSDVSVSLSFLVDTRAAAVTLSFTFGSGTTGTSPAGYVSVYRIE"
     gene            complement(8541..9296)
                     /gene="dapB"
                     /locus_tag="ACOIAP_001178"
     CDS             complement(8541..9296)
                     /gene="dapB"
                     /locus_tag="ACOIAP_001178"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGZ2638081.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELKLVCGVARSADEKSHHS
                     DTKLYKTMTDVTEKADVIIDFSHHETLEPILSYALKNNTPVVLATTGYDESDLSKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIKEVLPESTNTHGRYGRDCKRKANEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLVGKQSGLYKMSDILG"
     gene            9739..10728
                     /locus_tag="ACOIAP_001179"
     CDS             9739..10728
                     /locus_tag="ACOIAP_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGZ2638082.1"
                     /translation="MLKEEKTYQEKEAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLIFGLIFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAASRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(11011..11727)
                     /gene="dapD"
                     /locus_tag="ACOIAP_001180"
     CDS             complement(11011..11727)
                     /gene="dapD"
                     /locus_tag="ACOIAP_001180"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGZ2638083.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     CNGSYIFVGDYEDIMEVLDKHGNDIIDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(11909..12658)
                     /gene="dapB"
                     /locus_tag="ACOIAP_001181"
     CDS             complement(11909..12658)
                     /gene="dapB"
                     /locus_tag="ACOIAP_001181"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGZ2638084.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDSELELVCVAARGLDSYEDDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDEEMNKIHEAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(12726..13613)
                     /gene="dapA"
                     /locus_tag="ACOIAP_001182"
     CDS             complement(12726..13613)
                     /gene="dapA"
                     /locus_tag="ACOIAP_001182"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGZ2638085.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(13730..14731)
                     /locus_tag="ACOIAP_001183"
     CDS             complement(13730..14731)
                     /locus_tag="ACOIAP_001183"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGZ2638086.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     regulatory      complement(14909..15083)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(15161..16042)
                     /gene="dapA"
                     /locus_tag="ACOIAP_001184"
     CDS             complement(15161..16042)
                     /gene="dapA"
                     /locus_tag="ACOIAP_001184"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGZ2638087.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENDTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPEDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VAKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKHKLTNFGFKF"
     gene            16365..17558
                     /locus_tag="ACOIAP_001185"
     CDS             16365..17558
                     /locus_tag="ACOIAP_001185"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HGZ2638088.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            17763..18881
                     /locus_tag="ACOIAP_001186"
     CDS             17763..18881
                     /locus_tag="ACOIAP_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGZ2638089.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEIYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNVDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVNSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAVGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSALLKYKEAID"
     gene            19012..19257
                     /locus_tag="ACOIAP_001187"
     CDS             19012..19257
                     /locus_tag="ACOIAP_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HGZ2638090.1"
                     /translation="MKEKVQIEKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            19244..19990
                     /locus_tag="ACOIAP_001188"
     CDS             19244..19990
                     /locus_tag="ACOIAP_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2638091.1"
                     /translation="MSQYSDFAFVYDELMNEVDYDGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKDYDIAGIDISDEMLSVAKEKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKQDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENIIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLKE
                     SGFKDIKSYGDFTFDKPKEESQRIFFVCKK"
     gene            20274..21149
                     /gene="hslO"
                     /locus_tag="ACOIAP_001189"
     CDS             20274..21149
                     /gene="hslO"
                     /locus_tag="ACOIAP_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGZ2638092.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYTEEELLEILKEM"
     gene            21539..22339
                     /locus_tag="ACOIAP_001190"
     CDS             21539..22339
                     /locus_tag="ACOIAP_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGZ2638093.1"
                     /translation="MESKTKHIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRKLGVKPQNVIILADIDKKEGTHYELMKKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREHKIKDDLYFIKPKYVKYIPRNERAIYKAMEFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            22866..25106
                     /locus_tag="ACOIAP_001191"
     CDS             22866..25106
                     /locus_tag="ACOIAP_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2638094.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNDIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFSESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYKSLI
                     NGYNIADLTSMQIDELVEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHRGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPNAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNICEGKKFKKEVLEYRFQGKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIG
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIEMGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            25519..27054
                     /locus_tag="ACOIAP_001192"
     CDS             25519..27054
                     /locus_tag="ACOIAP_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2638095.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTVMTITGSILIALLALIFDFILGLVERFFQRKRKKKNRKKV
                     FAILGSLILIVTIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLKVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTENMFSKLQSEYKNKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNISDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVIVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            27070..27831
                     /locus_tag="ACOIAP_001193"
     CDS             27070..27831
                     /locus_tag="ACOIAP_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2638096.1"
                     /translation="MTTIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKRAVDKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNAPANQFVDQLLNIRKSIIDDENLKK"
     gene            27951..28202
                     /locus_tag="ACOIAP_001194"
     CDS             27951..28202
                     /locus_tag="ACOIAP_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HGZ2638097.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLDTNDVVNWCKTKIE
                     SPNAIINRKGKNWYISIYDCIITVNAHSYTIITAHKEKK"
     gene            complement(28515..29165)
                     /locus_tag="ACOIAP_001195"
     CDS             complement(28515..29165)
                     /locus_tag="ACOIAP_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638098.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSEVKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIAFPLYVDAIPSHLLHFLEECEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWIQGIGIGAGEMFGSLESVPLGKGQKKDLGIALKE
                     LSKNILSNNINIGNSKKNNIFISPNFPRFLYKLIGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(29162..29665)
                     /locus_tag="ACOIAP_001196"
     CDS             complement(29162..29665)
                     /locus_tag="ACOIAP_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2638099.1"
                     /translation="MKLLIHDLTDEELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPTECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKHINLEAIFYGNCITESEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(29714..30229)
                     /locus_tag="ACOIAP_001197"
     CDS             complement(29714..30229)
                     /locus_tag="ACOIAP_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638100.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQNHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKIDVEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            30509..31036
                     /locus_tag="ACOIAP_001198"
     CDS             30509..31036
                     /locus_tag="ACOIAP_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGZ2638101.1"
                     /translation="MHEQIDYCERKKIRTIDIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            31020..32423
                     /locus_tag="ACOIAP_001199"
     CDS             31020..32423
                     /locus_tag="ACOIAP_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2638102.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIIVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(32783..33094)
                     /locus_tag="ACOIAP_001200"
     CDS             complement(32783..33094)
                     /locus_tag="ACOIAP_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638103.1"
                     /translation="MKKIIKSFTFWFFLIALFEISMHQIGQDSKSIILIGFNPILSII
                     SRIDSFFIFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(33150..33743)
                     /locus_tag="ACOIAP_001201"
     CDS             complement(33150..33743)
                     /locus_tag="ACOIAP_001201"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2638104.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEIDDNGLLPGSRQHISGANYTVEIMKQAPVTIFIL
                     NILGKSLLENLSPEERFYEMANIQSIGASIQNMSLKAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLNDVTEWR"
     gene            34268..34498
                     /locus_tag="ACOIAP_001202"
     CDS             34268..34498
                     /locus_tag="ACOIAP_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638105.1"
                     /translation="MRLDMDSMLYVLIYMTLLVSVIGSIFYFCKDLLNHKIKYVLIKN
                     IFVNRTTYSEERLPKQYIVFQKYDIWRYCSLF"
     gene            34555..35205
                     /locus_tag="ACOIAP_001203"
     CDS             34555..35205
                     /locus_tag="ACOIAP_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HGZ2638106.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVNSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAMVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            35407..36078
                     /locus_tag="ACOIAP_001204"
     CDS             35407..36078
                     /locus_tag="ACOIAP_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2638107.1"
                     /translation="MAKILVVEDEKRMQSIIVEYMQKGGYTCVTADDGVEALTILKSN
                     NIDLMILDVMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTGIPKNSLILGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            36075..37205
                     /locus_tag="ACOIAP_001205"
     CDS             36075..37205
                     /locus_tag="ACOIAP_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2638108.1"
                     /translation="MSSLRKIIEKLKNLDISNWIKQNFGLHSVRKKVFLLSKLSGALI
                     ILFYLVVEELSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEADEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVVDKMRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLILFEIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVKNRDRGVEFYFMIPIDE"
     gene            37653..38498
                     /locus_tag="ACOIAP_001206"
     CDS             37653..38498
                     /locus_tag="ACOIAP_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638109.1"
                     /translation="MIKVEELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGNEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMAIDKPKNL
                     KMKNSNNKVEVEFVYNGSRDIKIVDIGELESGITFKYDEILSVHSKEATLEEVFIKYT
                     GRMLV"
     gene            38498..39526
                     /locus_tag="ACOIAP_001207"
     CDS             38498..39526
                     /locus_tag="ACOIAP_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638110.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSTSPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKEMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNVGFFEGIKILSQVLVQASILSIIMSLIGFGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYIQLKNAFFMNFSNELIYFVVCSLTIIVLFLLVKNIF
                     NKELVREG"
     gene            39529..40542
                     /locus_tag="ACOIAP_001208"
     CDS             39529..40542
                     /locus_tag="ACOIAP_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638111.1"
                     /translation="MIGLRYQLKSIRKDKMCIISFFLPVVMAILINFMGTIDMSSLGE
                     IHFGIVKDTLPVRTEQWLKKYGVLSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEILPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGVPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMLYIILDKKRKLS
                     FSR"
     gene            complement(41075..42325)
                     /gene="cme"
                     /locus_tag="ACOIAP_001209"
     CDS             complement(41075..42325)
                     /gene="cme"
                     /locus_tag="ACOIAP_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HGZ2638112.1"
                     /translation="MENKNINSTWKKRVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTICSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINGSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVMSINNLIIVAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(42411..43157)
                     /locus_tag="ACOIAP_001210"
     CDS             complement(42411..43157)
                     /locus_tag="ACOIAP_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2638113.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELSLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAICLVNQYLKQLEIEKSN
                     AEEALTIVTQILNGHTPETDKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(43272..44294)
                     /locus_tag="ACOIAP_001211"
     CDS             complement(43272..44294)
                     /locus_tag="ACOIAP_001211"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGZ2638114.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKIIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSTGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGAGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIIE"
     gene            complement(44294..46714)
                     /locus_tag="ACOIAP_001212"
     CDS             complement(44294..46714)
                     /locus_tag="ACOIAP_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGZ2638115.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLKPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEVKNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDEFLKILLDQGNLSTFGTNLVNNILSKTRHLIESRLGHLSLYREI
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGIEGGQLVYQGNLEGLLQSNKSLTGQYLSGKYSMPN
                     RTSTKNITHIDEIPCITVQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQTNSSESEIGDEDDYAVVETIADRLIGTKYISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSDCHGKRFNDESLSIKYKNKTIHDILNMSISEAVNFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRVKLAKEIGKKRNGNILYVLDEPTTGLSLYDTAK
                     LIQLLDELVANGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(46800..47720)
                     /locus_tag="ACOIAP_001213"
     CDS             complement(46800..47720)
                     /locus_tag="ACOIAP_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGZ2638116.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLFLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTITDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNVNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            48326..49240
                     /locus_tag="ACOIAP_001214"
     CDS             48326..49240
                     /locus_tag="ACOIAP_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HGZ2638117.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSTSTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSENS
                     NTEILTGNSGIFKNIEKYLDVTINNNQKTMKYKHRDELFKNSNTNTYSRINEEHIDKG
                     YDSIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLNYESPESIHEIIIRKL
                     NSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEPTILF
                     GYEFESYLSEESSLSACNYGDMCYEDMY"
     gene            complement(49442..50026)
                     /locus_tag="ACOIAP_001215"
     CDS             complement(49442..50026)
                     /locus_tag="ACOIAP_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGZ2638118.1"
                     /translation="MLFSKSLSIALEEYEEIEQFYSTQDIHSLSEMIQDKKIDIVLMD
                     INLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIGIYGFLNKNISPD
                     SLIDSLLKVYQGGTCFPSENTEVIIEDLTSMEKRILQLICSGKKRKIIADELYISERT
                     LSNHLQHIYDKLDVSSSVEAITKAIQMGYISPVY"
     gene            complement(50034..51617)
                     /locus_tag="ACOIAP_001216"
     CDS             complement(50034..51617)
                     /locus_tag="ACOIAP_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2638119.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTKTYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLVLDSWYLLLSFVATPIGTIIFKILSTVIAYVS
                     IKFIFLFLFQGSGYKFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHWKRVAFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRSIFLFISILVISLVVLFASGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPEVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNINDNGVKNTSFKTPLDITKITFDTIKHKGIISIKEQVENLGGTISISDNIPHGV
                     CVQITIPMKGDVSYKYFVS"
     gene            complement(51957..53984)
                     /locus_tag="ACOIAP_001217"
     CDS             complement(51957..53984)
                     /locus_tag="ACOIAP_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2638120.1"
                     /translation="MNIFYMAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKVM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENILTCSGAFIIGLVLGALVHKSIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAISNGKFLYKTSLIKLIRYEKSTEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWISIGFYQIGLITMIIIVIGTVLFINSFLPYIMQKSKKNKRAFYTGTK
                     IITIPNFIYRIRSNSKTLIMLTLLSAATLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYMSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGASKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLIKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYLLLINGKETPVTVRETSLNNAISFANSVGTLIVNDSIYEQIAQSKFPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIASG
                     SILYFNNISAISDSTSDYKILQKMGYTNIQIKKIIKKQVLPFFNIPFLLGIVDCIFAT
                     LVYKTALMQNLLGNSLSQYIPVIIAIFLTSVVYLIYYIFTIKSCCKIVLKK"
     gene            complement(53997..54743)
                     /locus_tag="ACOIAP_001218"
     CDS             complement(53997..54743)
                     /locus_tag="ACOIAP_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638121.1"
                     /translation="MNTILKVNSITKTYKGQQPSLDKVSFNVSEGEFIGIMGASGSGK
                     TTLLNVLSTIDKPTSGDIFINNINLKSLNDTNAADFRKDNLGFIFQEYFLLDSLTTFE
                     NISVPLTLQKLSPDKIEKMVKSLAERFGIASQLNKYPNELSGGQRQRTSAVRAIVKQP
                     SILFADEPTGALDSNSATELLHSLQEANKELKTTILMVTHDAYAASFANRILIFKDGH
                     IIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            complement(55034..56695)
                     /locus_tag="ACOIAP_001219"
     CDS             complement(55034..56695)
                     /locus_tag="ACOIAP_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HGZ2638122.1"
                     /translation="MNKKNLAILISGIMFFSSSSSIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIESSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKALNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSVNFLNSRSIKKSYIVGGNKILSD
                     NAVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGISQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIENKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQTLPGSDILVCYYDEDDNEYDCKVVKDNVLYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTKNISLDKAKAIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIIDIDMDNDSDDDIDDNDNNHNNNSNTNDNSSIISAEKAKSIILDKVP
                     GGKIVKFKYDEDDKEYKGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            57294..57671
                     /locus_tag="ACOIAP_001220"
     CDS             57294..57671
                     /locus_tag="ACOIAP_001220"
                     /inference="COORDINATES: protein motif:HMM:NF012472.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGZ2638123.1"
                     /translation="METKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTVATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFD"
BASE COUNT        21279 a         7286 c         9312 g        19912 t
ORIGIN      
        1 cttattaatt gtataacagt aattttataa ttaatacaaa actgaaatag atagtttaat
       61 tagtatatat ggtacaaaaa gatagtaatt ttataattat aaaagtgaaa tattaaatga
      121 aatttataac caaataaaaa cttttaaaca gcaatcaaag atttgtaata aaatacatcc
      181 cttataaata tatttattat ataagctgat accagaaata taagaattaa caattgtgga
      241 gggataaaat atgatagctg ttaaagatga gaataacgta gtaaacttaa gaggggagtt
      301 agacaataag ctagaattta gccatgagat atttggagaa aaattttata atatgaaaat
      361 aaaaataaac agattaagcg attcttttga tatacttcca atgactgtat cagaaagact
      421 tctccaagat attgaccttg ataaacaaaa tttagtcaat gtcgtaggtc aattaagatc
      481 atataataaa acattaaata ataaaaatag attagtgctt acagtgtttg tcagagaaat
      541 aaaaagcata gacgaggaaa ataaagaccc taatagtata tttttagatg gatatgtatg
      601 taaggaacct gtatatagga agacaccttt aggaagggaa ataaccgatt tattagttgc
      661 tataaacaga ccttataata aatctgatta tataccatca atagtttggg gacgaaatgc
      721 taagtttgca aagaatctaa aggttggtga taggatacag ctttggggta gggttcaaag
      781 tagagaatat gagaaaaaaa tagatgaaaa taatgtggtt aaaaaaatgg catatgaagt
      841 atctatatcg aaaataaaaa aattggatga aaataacaat gaataaacat aaaaagtaga
      901 ctgactttta tgaataaaat cctaataagt ttggtataat atcatattaa aatatataaa
      961 gattgtttaa aaaaatacta atgaaatatc tcttgaatag ttgctcgcca tttattataa
     1021 tgtaatctgt acataattta taattgagga aatgaagagg tgaagcattg tgaaaagcat
     1081 attatgtcag ataaataaac agccagttaa agctaaatat acatctgatg aattagaatg
     1141 ttttttggat acaattgagt ataatgtagg tgataaaata ttgcttgttg gtcatatagg
     1201 aaacctaggc aagagattga gaggtcttgg aacttctgta actatactgg agaatagtaa
     1261 ctatgaagat gtatgttatt ctctagtgta taatgaaaat tgcaatgtag ttaaaggtaa
     1321 gttagagttt ctaccgtttg atgataatca gttcaacaag ataataatag ttgaccaatt
     1381 taatgttatt acagattgtg aaaaagcttc atctgaaata caaagagtac taaagggcaa
     1441 tggagaggtt atattagagg atttaaactt aaagaattta aaagttaagt taaattatct
     1501 taaacataaa ttttgtggtt ctgttgcaaa gattcactat ccacatgaag tgttcaatat
     1561 attttcaaga ttaaactttg atggtatgat taaagagtca aataaattaa aatatattta
     1621 tgtgggaaaa agaagataaa tgagttaaaa tataaatatg gatataatat aaaagactag
     1681 gttaagccta gtcttttgtt ataaggagat gtttagatgg aaataaatta tgagttaata
     1741 ataattgtta tgctctttgt aatcctaatg tcaatccaat ttactttaaa taagatatac
     1801 ttgattctta aagaaataag acaaatactt atgttaaaga aaaataagga atgatgatta
     1861 tgataggttt agaatatata aaatctgata ttcaaaatat agctgaagct atagtatcag
     1921 tactcaatat agatgtaact atagtaaata aggacttatt taggattgca ggtacaggag
     1981 tatatataga caaaataggt gagaaagtag ataaatatac ggcttttaaa aaatcactta
     2041 cagagcagat tacaatacta attgatgacc caaagagtag tgatatatgt agggaatgct
     2101 ataaaagtgg ggcttgtgta gagtttgcag aggtgtgttg tcccattata tgtgatggag
     2161 tctctcatgg tgttataggc cttatagcct ttacaaagga acaagcacag attatagaaa
     2221 ataataaaag tggtcttata aactttttag gcaaaatggc agacttaata tctaataaat
     2281 taaaagctca aattaaaacg tatgagcttg aattagaaaa gaaaaaatta gagacactgt
     2341 taaacaatat ggacaaagct gttgtgtcta ttgatgtaga cggaaagatt gataaatata
     2401 attcgaaatt taaagagctt ttcaatataa aagataatat aactggtaaa aacatatttg
     2461 tcgaattaga ttttataaag aaaccttcta taaataactt taagaaggat aaatcctgta
     2521 gtttttttta taaaagatac ggatatgatt caaagggaat atataacatc aataaaatag
     2581 tcttaaaaaa tgagttaaag ggatatgtta ttgattttat agataaaaga gatgctataa
     2641 aaaactacaa taagatgaat aaagattata ggataaaatt ggaaaatata attggggaaa
     2701 gtgtagctat aagaaattct aaaaaagagg ctttaatagc ttctaaatca acatcaacag
     2761 tgcttattac tggtgaaagt ggaacaggta aggagctatt tgcaagagcc atacacaacc
     2821 atagcaatag ggtagataat ccttttatag ctgtaaattg tgctgctata ccagacaatt
     2881 tattagagag tgaattattt ggatatgaag aaggagcttt tactggagct aaaaaaggtg
     2941 gaaagcttgg aatgtttgaa gtagctcata aaggaagtat atttttagat gaaataggag
     3001 atatgagttt gcatttacag tcaaagttat tgagagtatt acaagaaaag gaactcaata
     3061 aaattggaag taaatcaaat gtttcaatag atgtaagaat tatcgctgca acaaataaag
     3121 atttagaaaa aatggttcaa aatggaactt ttagagaaga cttatattat agattaaatg
     3181 ttatacctat aaaattacca agtttaaaag agagaaaaga agatatccca cttataatca
     3241 aacatatggt taaagagtat tcaaaaaaat tagataaaaa tgttattgac atagatagca
     3301 gagttgtgga tgctatgatg gaatataagt ggccagggaa tataagagag ttgcagaata
     3361 ttattgaata tagtgtgaat atgtcctcct cttcaataat cacaatgaat gtaattcctc
     3421 aaaaaattaa gaatacctct gtagaagagt tggaagttag aagcgatagg ataattccac
     3481 ttgatgaact agagaaaatt gagataataa aagctttaaa taaatacaaa gactataaaa
     3541 aagataaaga attaacagct aaagcacttg gaatatcaag agctacatta tatagaaaaa
     3601 ttgaaaaata taatataatt tcatagtaat ataataaaaa actgtataaa atttaaattt
     3661 ttctaaatgt ataactttaa agaaggattt aaatttctat tgtaagtgtt ttgcataatc
     3721 ttttttatga attaaaaaat agtttttata agttaaaaaa taatatgttt gagtcgtctc
     3781 aaaatgatat agaatctcat tttgagactt ttttttgtct ttttgcgaaa ttgtcatatg
     3841 tttctccatt ttaaagaata taaatatcct atgcaaataa aaaaaatgca taaatagaag
     3901 tagtcatacc aatggctata gaatataaaa ttaaaaatat aaacagatat aaaaaatatg
     3961 gcatgtattt tgctatacat atagataaga aattatttaa ttaattattt gagtactaaa
     4021 tctaaactta attgggaggt ttatatataa tgagagatat aagaaaagaa ttagtggaaa
     4081 tgttaaaggc agaagttaag ccagcagtag gatgtactga accagtagct ttagctctag
     4141 catgtgcaaa ggcaaaggaa ttattaggag aagaaatagt tgaaaaccga atgttagtta
     4201 gccctagtat ctataaaaat ggtatgtgcg taggtatacc aggtactgaa agattagggt
     4261 taaaaatcgc agcagctcta ggtatagtag gtggacattc tgaaaacgga ttaagtgtgt
     4321 tagagactct aacaaaagag gaagttaaaa tagctgagga ttatatggat aatactcctc
     4381 tatcaataac acctgctgat acaagagaga aagtgtttat agaagttgta ttaaaaggaa
     4441 aaaatcatat tgctaaagtt agaataagaa ctaaacatga taattttacg ttcttagaaa
     4501 aagatggaga agtattatta gacaatgaac caaaagtatc agcttcaaat gattcagcag
     4561 aaaaagttga aagtttaatg gatacagtaa ctatacaaga attaataaaa aatgtagaag
     4621 gcattgattt taaagatata gaatttttac tagatggagt aaaaatgaat gaagaaatgg
     4681 ctgaatatgg attaaaacaa aaaactggta ttggtgtcgg atatggaatt aaaaagtcta
     4741 tagaagaagg tcttttaggc aatgatgtta taaattatgc aatgatgtta actgctggag
     4801 cttcagatgc aagaatggca ggggtaaaaa tgcctgttat gagttcaaat ggaagtggaa
     4861 accacggatt aacagcaatt cttccaatcg ttgcttacaa taaaaaattc ccacaatctg
     4921 atgaaagact agcaaaagct ttagctatat ctcatttagt aactggttat attaagaatt
     4981 atacaggaag attatctgct gtatgtggat gtggtgttgc tgcatctact ggagcaactg
     5041 ctggtatctc ttggcttatg aatggtactg aaaagcaaat agaaggtgct atagaaaata
     5101 tgatagctga cttaagtgga atgatatgtg atggtgcgaa agctggttgt gcactaaaat
     5161 tatcttctgc tgcatctgca gctatacaaa gtgctataat agccaagcaa gattgttttg
     5221 taccaccact aaatggtata gttggttcaa gtgttgagca aagtatacaa aacttaggta
     5281 gagtaagtga caaaggtatg tctataacag atgaaataat cttaaatgta atgaatgata
     5341 tgaataaagt tgactagtac tttataatat ggttttgtat tatgaagaat aacaaaaaca
     5401 gcataaataa atttaattag taccctctaa taaaatatga ttatgtataa atttatgtat
     5461 aatagaaaaa acttgttagt gcaagttttt tctttttttg tctaaaatat atagtatgta
     5521 atttagtatg gatatatgaa ctacttaaaa tataagatac cttgttaata attgttgaat
     5581 gaacataaaa actcaataat attggctaat attgaataag agtattgaaa aagtgagcaa
     5641 tctcttataa aattaagaag gattattaca attggaggtc tttttatgga tatagaaaca
     5701 aaaaaatggg aagtgttgta ttcagaagaa aaaattaaag ataaattaaa agaattagga
     5761 gcaattatag aaaaagatta taaagataaa aatcttatgg tagtttctct attaaaaggt
     5821 agttttatat tttgtgcaga cttagttaga aatataaatt taccacttag agtcaatttt
     5881 atgactacat ctagttatgg aaataatgaa gaaagtactg gaaaggttaa agtagtttca
     5941 gatgttacta ctgatatagc aggatatgat gttttagttg tagatgatat tactgattct
     6001 gcacttacta tggattttgt gttaaaacat ctaaaagcta aaaatcctgc tagtttaaaa
     6061 tgctgtgttc ttttggataa accaagtaga agaaaagtcg atttagtgcc agattattgt
     6121 ggatttgaaa tagaagataa gtttgtggtt ggatatgggt ttgattttgg cgattattat
     6181 agaaatgttc cttatatatt caatgtcact gatgaagata gataagcaat tatatgattt
     6241 tgtggatgcc ttaatatgat ttttattaat cgtgttgagg tttttttatt taaaaagcaa
     6301 ttaaagtagc attaaattaa tcttgtgcag ttcaactata tcttttttat aacataataa
     6361 aaaaatttca aatgattggt gggaaatgaa ttttttaatt gtatttataa ttgtaaaata
     6421 ttttataaaa atgtgatgac atctaagaat aaaagaattg atgttgatat aagtaaatag
     6481 atacattatc acataagaaa ttgtcgattc atataattat atagagtaat actcaatatt
     6541 tatagagtat tactctaact ttaaaaaggg aggataatta tatgagtgat atttcaggtc
     6601 caaatttata tcaagatgta ggtccaacag gtccaacagg tccaacaggt gctactggtc
     6661 caacgggtcc gactggacct agaggtgcaa ccggagcaac gggagcaaat ggaataacag
     6721 gtccaacagg aaacacagga gcaacaggag cgaatggaat aacaggtcca acaggaaata
     6781 tgggagcgac tggaccaaat ggagcaacag gttctacagg tccaaccgga gcaacgggag
     6841 caacgggagc aaatggaata acaggtccaa caggaaatac gggagcaacg ggagcaaatg
     6901 gaataacagg tccaacagga aacaaaggag caacgggagc aaatggaata acaggttcta
     6961 caggtccaac aggaaataca ggagcaaccg gggcaaatgg aataacaggt ccaacaggaa
     7021 atacgggagc aaccggagca acaggtccaa ctggactaac cggagcaaca ggggcaactg
     7081 gagcaaatgg aataacaggt ccaacaggaa atacaggagc aacgggagca aatggagtaa
     7141 caggttctac aggtccaaca ggaagtacag gagcaacagg cccaaccgga gcagtaggag
     7201 caaccggagc aaatggagtg acaggggcaa caggtccaat aggagcaaca ggtccaactg
     7261 gagcagatgg agaggtaggt ccaacaggag cagtaggagc aacaggtcca gatggagtaa
     7321 taggtccaac aggcccaacg ggagcaaccg gagcaactgg agcaaatggt ttggtaggcc
     7381 caacaggccc aacgggagca accggagcaa atggtttggt aggtccaaca ggcccaacgg
     7441 gagcaaccgg agtagctggg gcaataggtc caaccggaac agtaggagca acaggcccaa
     7501 ctggagcaga tggagcagta ggtccaaccg gagcgacagg agcgacaggg gcaaatggag
     7561 caacaggtcc aaccggagca gtaggagcaa ccggagcaac gggagtagca ggtccaatag
     7621 gtccaacagg tccaacggga gcaaatggag tagcaggagc aaccggagcg acaggagcaa
     7681 ccggagcaaa tggagcaaca ggcccaaccg gagcagtagg agcaaccgga gcaaatggag
     7741 tagcaggtcc aataggtcca acaggtccaa ctggagcaaa tggagtgact ggagcaacag
     7801 gaaatacagg agcaacagga gcaaacggag caactggtcc aacaggagct actggagcaa
     7861 ctggagtgtt agcagcaaat aatgcacaat ttacagtatc ttcttcaagt ttagggaata
     7921 atacattagt gacatttaat tcatcattta taaatggaac taatataact tttccaacaa
     7981 gtagtactat aaatcttgca gttggaggaa tatataatgt atcttttggt atacgtgcca
     8041 cactttcact tgcaggattt atgtcaatta ctactaattt caatggagta gctcaaaata
     8101 attttattgc aaaagcagta aatacgctta cttcatcaga tgtaagtgta agtttaagtt
     8161 ttttagttga tactagagca gcagctgtta ctttaagttt tacatttggt tcaggcacga
     8221 caggcacttc tccagctgga tatgtatcag tttatagaat agaatagttt atataatgaa
     8281 aggactataa aataataaac aatatgattt tatatactaa taaataatat aatttttaat
     8341 aagtctatat ggtgaaaata ctgtaaaata atgaacaata tagttctata tactaaaata
     8401 atataatctt tagcagaatg actatattaa aaagtaggta taaaatttat aaacttttag
     8461 agtagaaatc tcaatcaatt agatattcaa attgatgaat atgaatatcc aaatagattg
     8521 agatttatta tgtacaaaat ttatcctaat atatctgaca ttttataaag tccagattgc
     8581 ttaccaacta aaaatttagc tgcaactata gaaccgtttg caaatacttc atcagattga
     8641 gaatgatggc ttaaagtaag aacttcatta tcacctgcaa atataacatc atggtcactg
     8701 attatattgc ctcctcttat ggagtgtatt ccaatttcat ttgcttttct tttacaatcc
     8761 ctaccatatc tcccatgtgt atttgtgctt tcaggcaaga cttctttaat tgcattagct
     8821 atcatagtag cagtcccact aggagcgtct tcttttctat tgtgatgctt ttctatgatt
     8881 tcaatatcaa aaccttctaa catctttgaa gcgtccttaa ctaattttat taatatatta
     8941 actccaagag atgtatttga tgataataat ataggaatat tttttgatgc ttcctctatt
     9001 ttacttaaat cactttcatc atatccagta gtagctaata ctacaggcgt attatttttt
     9061 agagcgtatg acaatattgg ctctaaagtc tcatgatgtg aaaagtctat tatgacatca
     9121 gctttttcag ttacatcagt cattgttttg taaagctttg tatcactatg atgacttttt
     9181 tcatcagcag acctagctac accacaaacc aactttaatt cattatcttt ttttacacat
     9241 tctgctaaca ctcttcccat tgttccatta tagccgctaa ttataacttt caacataaat
     9301 tcctcctata aaattaataa aaatttgttg tatttctata agtttatttt atcactaata
     9361 ttatctatat aaaataatat tagtgataat aggtttacaa tttatcttac attaaaaaat
     9421 tgaagtagct ttgtcaaagt atagataagc tttttttcac tgttgaaatg ataaaaatat
     9481 atttggtttc atacaaaaaa gagaacctca tgaatcaaaa aagttcattt tgagatacca
     9541 cattcatata tcgtataatt tatttaaaaa tcaatattaa tacattaaaa taactaagca
     9601 catgtatgta taaagatgta tgaaaaatat ataaatacat tatagtatta atttcaaatt
     9661 caacaattta agtgttaaaa gtgttattat taaattagaa acatcttaac ttaatatact
     9721 gagatgggag tgatagatat gttaaaagaa gaaaaaactt atcaagagaa agaagcaaaa
     9781 gtatttaatg gagtagcagc tttgataatg attgtgttat ttttagtagt ttcaataggt
     9841 attatggttt ttgggatagt aaaacttgat agtggattta ctggaatagg ttcacttatg
     9901 ttaatttttg ggcttatatt tatagtagta gattttattc tattctttgg gctgaaaatg
     9961 attaatccta aagaggctat agttttagtt ttgtttggta attattatgg aactataaaa
    10021 aaagaagggt actattgggt gaatccattt tgttcagcaa taaacccagc agcatcaaga
    10081 attaatgtat caaaatcttc atctgacgaa aaagtagata tatcaactaa ttcaagaggt
    10141 aagaaagtat ctttaaagac aatgactctt aataatgaaa aacagaaagt taatgattta
    10201 ttgggaaatc caattataat aggagttgtt gtaatttgga aggttataga tgcaacaaag
    10261 gcagtattta atgtggataa ttataacaca tttttatcta ttcagtgcga ttctactatt
    10321 cgtaatgttt caagacttta tccatatgat gtgtctgaag atggagatga aaaatctctt
    10381 cgtggtagta gtcaggaaat agcagataga ttaaaagatg aattacaatc aagggttgat
    10441 attgcaggaa ttgaagtatg cgaagtgaga attactcatc tttcttatgc tccagagatt
    10501 gcagcagcaa tgttacaacg tcaacaagca gaggctataa tagcagcacg taaaaagatt
    10561 gttgaagggg ctgtaagtat ggtagagatg gcattgacta atttaagtga aaataatgtt
    10621 gtaactttgg atgaagaacg taaagcagct atggtaagta atctgttagt tgttctttgt
    10681 ggcaataaag atgcacaacc agtagtaaac agcagttcta tttattaaat tatataaagt
    10741 ttagtagttt actttattgg tttatataaa gttcgctagt ttgtttcatt gatatattga
    10801 aaaattgaag gaaataaaaa tacttatcag aaagaaataa aaatgatatg agaatgaata
    10861 agagaattat aaaaataaat aaaagataaa aatattataa aaaagggtgt ctctaatgaa
    10921 ttaaattcat atagagacac cttttaatta atttttaaat tagtatatta ttatttaatt
    10981 aatcttttca attaatatat tgtcatttaa ttaatctaaa tttctaaggt cttccataag
    11041 tttagtcttg tcagccgttt tttcgtcttt catttttata actttagcag gagaaccagc
    11101 aacaacagca ccagcttcta catcagtagt tacaacagca ccagctgcaa caacagcacc
    11161 tttaccgatt ctaacacctt caagaataac tgcattagct cctattaaaa catcatcttc
    11221 aactataaca ggagtagcag aaggtggctc taaaacacca gcaacaacag caccagcacc
    11281 aaggtgaaca tttttaccaa gagttcctct agctccaata acagcattca tatctaccat
    11341 agaaccttca ccaataacag ctcctatatt tataacagct cccatcatta caacagcatt
    11401 tttttctata gtaaccatat ctcttattat tgcacctggt tcaattcttg catgttcact
    11461 taaagtattt tttagaggaa tagcagaatt tcttctatca tattctacat gagtatctat
    11521 tatgtcattc ccatgtttat ctaatacttc cattatatct tcatagtcac ctacaaatat
    11581 ataagaacca ttgcatccaa ataccttaaa tttatcagtt gattggaaat gtaaagagtt
    11641 agtatttaca tataccttaa caggtgtttt ctttttaact tcttttatat accttgctat
    11701 ttcataagca tcgtttaaat ttaccatttg ttaattctcc ttgtatttca ttatatttct
    11761 tttattatat acttgtttgt caattttagt atatatttac ttcttattat ttatatttta
    11821 attagttttt attatataga catagtatta agtaaattta tctattatat atgtttgatt
    11881 tatattgtgc attattatac ttatattatt atcccaacat gctgtccata ttataaaatc
    11941 ctggtttttg tttaactaaa tatttggcag cagctataga accacttgcg aagataccac
    12001 gagattgagc ttgatggctt attgtaagaa cctcattgtc tccagcaaat aaagcatcat
    12061 gttcgccaac gatatttcca cctcttatag catgaatacc aacttcattt ggttgtcttt
    12121 tcgcactacg gccatatcta ccataattat tttcaacgtt tggcaaaact tcttttatag
    12181 cgttagcaat cataacagct gtgccacttg gggcatctac ttttctgttg tgatgttttt
    12241 ctattatttc tatatcaaat ccttctagta atttagctgc atctttaacc aattttacta
    12301 atacatttac accaagagac atattatatg attggaatac aggaataact ttagctgctt
    12361 catgtatttt gttcatttct tcatcattat atccagtagt agcaattact aaaggtgtct
    12421 tagtctttaa aacgtaagat aagatattat ctaaattaga gtgatgagaa aaatctataa
    12481 ctacatctgc ttcttcaact atagtgctca tatcttcata gattttaagg tcgtcttcat
    12541 aactatccag acctctagct gcaacacaaa ccaattctaa ttcactatct tctcttatag
    12601 tatcggctaa aatcttaccc atttttccat cataaccagt tgctataact tttaacataa
    12661 tttcctccta tgattaaggg ctaacttttg accaaactta tcattttacc atgcattaat
    12721 ctttactatg cattaacttt tagtccaaag ttaactaatt ctttctttaa cacttctaaa
    12781 tttgctgggt ccatttctgc tagaggtaat cttaaatctc caacattgaa tcccaataaa
    12841 ttcattgcag tcttaactgg tataggattt acttctataa ataaagctgc aattagagca
    12901 tccataccaa gttgtaattt tctagaacct tctatatcgc cttcaaagaa tttagctacc
    12961 aaatcgtgag tttcttgagg gcaaacatta gcaagtactg atataactcc ttgacctcct
    13021 aaagataata aaggaagtat agtatcatca ttaccagagt agatagcaaa gtcatctgga
    13081 actaaactag ctatttctgc aacctgtcct aggtctccac tagcttcttt tacagcaact
    13141 atgttatcaa ttttagcaag ttcaactata aggctaggac ttatatttac acaagttctt
    13201 ccagggacat tgtaaagtat aattggaagt ttaacactgt tagctattgt ttcaaaatga
    13261 cgcttaagtc cagctttatt agctttattg taataaggag ttattattaa tagagcatct
    13321 actcctaatt tttcagcttc ttgacttaag ttaactgagt gcatagtatc attagaacca
    13381 cttccagcta taacaggaac tcttttatta actttttcaa caacatactt aatagtagca
    13441 agttgttctt catcagtcat agtattagct tcaccagtag taccacaaga tactatagca
    13501 tcagtaccat tagctatttg gtactcaact aattcaccta atttgtcaaa atcaactttg
    13561 ttatcctttg taaatggtgt aactagagca acagcagaac ctttaaatat catataaaat
    13621 caatcccctc ttttttattt ttgtgtttta tattacagtt acttctaatg cttgtttttg
    13681 agttactatt aatattttac aaaattatat atttatacaa gtttgtatat tatactaaat
    13741 cgtatgataa agccatttca gctatttgaa ttgcgttagt tgcagcacct tttcttatat
    13801 tgtcagcaac aacccaaagg tttacaccat tatcaacact aaaatctctt cttattcttc
    13861 caacaaatac ttcatctcta tcatcaaatt ctacagcagt tggatattcg tttttagcag
    13921 gattatcaac tactacaaca cctggagctt cttcaagtgt ttttactaaa tcatctaatt
    13981 caaatggatt gttaaactca acatttatag attcactatg accatttttt actggaactc
    14041 ttacagtagt tgcagttatt tttaaatcat agttatcaag tattttcata gtttcattta
    14101 ccattttcat ctcttcttta gtgtatccat tttcagtgaa tgaatctata tgaggaagac
    14161 agttgtaaga gatttgatga gggtagaatc cagtaggatt accgttcatt cctttctcta
    14221 aatcttcaac ccctttaaca ccagaaccag atacagcttg gtaagtagag taaacaactc
    14281 tcttaatttt gtacttatca tcaagagctt taagagggac catagcttgt atagtagagc
    14341 agttaggatt agctattata cccttatgat tttttatggc ttctggatta acttcaggaa
    14401 ctactaaagg tacatctgga ttcattctcc attggctaga gttatctacc actaagattc
    14461 cattcgaagc agctattgga gcatactttt cactaatact tccaccagca gagaataatg
    14521 ctatttgtat gcctctatca gtaaatgaag tttcctttaa ttcttctact atatattctt
    14581 taccacaaaa cattacttta gaaccagctg atttagaaga agagaataaa aatagatttt
    14641 ctattggaaa atttctttct tctaatactt ttaaaaatgt tctacctacc attccagtag
    14701 caccaactat tgctacattt acttttttca tataaattca ccccaatttt aaattataaa
    14761 aacattgttt tatttgattt tagtaataca agtaagatat gttaatattt ttatatatcc
    14821 aaaaacttta atattatatt aacaatttta attatataca aaaaacgtac aaaggtatac
    14881 tttgtacgtc taatttatca ctcaaagtaa accctgtagc tcatcaccta caaaaataag
    14941 tgacagtatt acacatgtta tgtgcaatcc cagaaaatat tattgcaaga aatattttct
    15001 tcggctgtaa atcctttttc caatcattaa cacctgccag ctactattgg atactcttag
    15061 ttacagctac ctctacccta ggttaatagg atattaaaat ttgattattc taataataat
    15121 acatatttaa gaaaaaatca acttatttat ataaatattg ctaaaattta aatccaaaat
    15181 ttgttaattt gtgttttaac acattaagat tagtttcttc catttcagct agaggaagtc
    15241 ttaaatcacc aacattaaaa cctaaaatgt tcatggcagt tttaactgga actggattta
    15301 cttctataaa taaggcagca attaaagcat ccatatcaag ttgtaatttt tttgagcctt
    15361 caatatcacc ttcaaagaat ttagctacta aatcatgtgt ttctttagga catatgttag
    15421 caagaacaga gataacacca cttccgccta atgataatag tggtagtata gtatcatcat
    15481 taccggagta tatagcaaag tcttcaggta ctagtttagc tatttctgca acttgagcta
    15541 agtctccact tgcttccttc acagcaacta tattatctat tttagcaagt tcagccacaa
    15601 cagatggctt tatattcact ttagttcttc ctggtacgtt gtataaaata attggcaact
    15661 taacactatt tgctattgtt tcaaagtgaa gtttaagacc tttttcatta gtcttattat
    15721 agtaaggagt tattattaaa agaccatcca cccctaattt ttcagcttct tgactcatat
    15781 gaacagacaa catagtattg tttgaaccag tacctgctat aacaggtatt ctcttattaa
    15841 ctttttcaac tgtatatttt attacagcaa aaatttcaga ttcactcata gtagtcgcct
    15901 cacctgttgt tccacaaaca actagtgcat ctgtgtcatt ctcaatgtgg tattcgatta
    15961 attcacctaa tttttcaaag ttgacattat tatcctctgt aaatggggta actaaagcaa
    16021 cagcagaacc tttaaataac atataatcaa atctcctttt ttatctaaat ttaatttttt
    16081 aagtacaata ataattatag tacaaattaa ttaattttaa taggtatagt taatatctta
    16141 actgtttaaa taagatattt atattatatt aatattagaa aaattttaaa taaatgtttt
    16201 attctcaaaa tatgcatatt aatttaataa aatataccaa aatgggaata aaaaataaat
    16261 tttatgagaa tttaataact aataattaat atatttaggt tataataaat atgtgcgtaa
    16321 aatctaataa taagcaataa tacagtaaat ttaggaggaa taatatggat actttaaagg
    16381 aactttttaa aataggaagt ggaccttcaa gttctcatac tatggggcca caaagagcag
    16441 cagagagatt taaaaatgaa aacccagatg cagaaagttt tagagcaata ttgtatggta
    16501 gtttggcagc tacagggaag ggtcacttaa ctgactatat aattgaaaaa actatagcac
    16561 ctaaaaaagt tgaaattgtt tgggaagaag atattataaa agattttcac ccaaatggga
    16621 tgaagtttga agctttagat aaagataaaa atgtaacagc tgaatggact gtatattctg
    16681 taggaggagg gactatagca gaagaaggtc aaagaaacag taaaagcaat agtatatatc
    16741 acttagatac tatggatgaa atagtaaagt ggtgtaaaga aaataataag actttggtag
    16801 attttgtctt ggaatgtgaa ccaaaagaca taaaagatta tataaaaact ataaaagatg
    16861 ctatgagaaa atctattgat gatggactaa gtacagatga aataatacca ggcaaactat
    16921 tattaaaaag aagagcaagt acattttata atgcatataa aaaagataag agtttctcaa
    16981 cgcttgtata tgcatatgca ttagcagctt cagagcaaaa cgcttctggt aatataatcg
    17041 ttacagcacc aacttgtggt tctgctggag taataccagg aatattcttt gcaatgcagg
    17101 atttctataa ttatgatgac gaaaaaataa ttgaagcact acttgtagct ggaataatag
    17161 gtaatataat aaaaactaac gcttcaatat ctggagcaga ggtagggtgt caaggtgaag
    17221 ttggagcagc ttgttctatg gcagcggcgg cagtagcata cttaaagggt ggaactatag
    17281 accatattga atatgcggca gaaatagcac ttgaacatca tttaggaatg acttgtgacc
    17341 ctgtatatgg gtatgtacaa attccatgta tagaaagaaa tgctatggca gctcaaagag
    17401 cttatgatgc agctaattat gcattattaa ctgatggctc acattctgtc tccttagacc
    17461 aagttgttga aacaatgaaa gaaactggta tagatatgat ggataaatac aaagaaacag
    17521 ctaagggtgg acttgctaaa catttcttct cttgctaaaa ataaaatttt ccaataataa
    17581 ttcccctgtt ttgatttatg aaacagggga attattatta atggtgaatt atttaataat
    17641 gcaaaatatt tttatattca tttagttttt tatttttaat tagtataaca tgttatataa
    17701 tattttaatt ataaagaaat atagaaatat tttttaataa attagaaatt ggaggagatt
    17761 acatgagaga ggcatcatat ttacaagaac aactttataa acataggaag tcattaaatc
    17821 ctattgcaga gattgggaga aaagagtata agacttcaaa gtatataaga gattaccttg
    17881 ataaattggg aattgagtat gaaatttatt tagaaacagg tatagtaggt gtaatagaag
    17941 gtaaaagacc taaaaaagat attgctttta gagctgacat agatggtctt catagtgaag
    18001 aaggggtaaa acatttatgt ggtcatgatg gacatgctac tatattactt ggattaattg
    18061 agtatttaaa tgataataaa gaagacttaa atgataatat agtatttata ttccaaccag
    18121 cagaagaagg tcctgggggg gcaaaagctc taatagatga aggcgtgctt agaaaataca
    18181 atgttgatga aatatatggg cttcatatat atccagagtt accagaaggt tatgtaggta
    18241 caagagaagg ctattttatg gctcaaatag gagatattga tatagaaata gtgtctaaaa
    18301 gtggacatgg agctatgcca caaaatggta ttgatggtat agtgatagct tcaaattttg
    18361 taaactcact ccaaactata gtgtctagga atataagtcc aatagacaat gcagtgttaa
    18421 ctattggtag aattgaaggg ggagctagaa gaaatataat agctgaaaat ataaagatgg
    18481 aaggcactat gagatgcttt agcccagaag tttatgagaa aatgaagctt agagttagag
    18541 aacttgctag agggtttgaa ttggcttata actgtaaggt taatataaat attatagatg
    18601 attatattgc tgttaaaaat gacaaggatt tgtatcaaga gtttgtagag gctgttggaa
    18661 gtgatactgt tgtagagtta gagccactta tgatatcaga agatttttct tattatcaaa
    18721 aagaagtacc aggattattt tttatgttgg gttcaagaaa cgaagaaaaa ggatttgtaa
    18781 atggtcttca taatataaat tttaattttg atgaaaagat atgtgtaaat gcattgaatg
    18841 tttattcagc gttattaaaa tacaaagagg cgatagatta gaaagataaa ttataaagat
    18901 taaaaagtag aaatacctaa atttaaaaaa agtgtagtga taaatacccc ttacatattt
    18961 gtataaattt attttaattg acaaaaatac aaataagaag gggtgatttt tttgaaagaa
    19021 aaagtacaaa tagaaaagaa gataactaat ggcaagaata ctaaaatatt gacaaatgat
    19081 gatataatga aatatgagat agcctcagaa ctaggtctta tggacaaagt tggtgaacgt
    19141 ggatgggcag gtcttacagc taaggaagca ggaagaattg gaggtatgct tacatcacgc
    19201 aaaaagaggc tgaaaaagat tgtggaggag cagaataaaa aggatgagtc aatatagtga
    19261 ttttgcgttt gtatatgatg aacttatgaa tgaagttgat tatgatggat gggttaaata
    19321 tatagaagat ataatagata gtgaaggtgt aaaagtaaaa aatatattgg aattggcgtg
    19381 tggtacgggt aatcttacaa ttccattgac taagaaggat tacgatatag ctggtatcga
    19441 tatatctgat gagatgctta gtgtagcaaa agaaaaggct gaaaaagaag gagtagaatt
    19501 agttttactt caacaggata tatcagagct tgattttgaa atatctgatt tggactgtgt
    19561 actttgtgct tgtgatggat tcaattatat aacttatgat gatgatttgg aaaatgtatt
    19621 ttcaaagaca tatgaattat taaagcaaga tgggatattt atatttgata taagttcatt
    19681 ttataaatta gccaacatat tgggaaataa tatgtatgga gaaaatagag aagatatagc
    19741 gtatatgtgg caaaattact ttgatgaaga agagaatata attgaaatgg aacttacatt
    19801 ttttattaaa gatgagtgtg gaaagtttga aagatttgaa gagatacacc aacaaagagc
    19861 atatactgaa gatgagatag ttgatatgct taaagagtct ggatttaaag atataaaatc
    19921 ttatggagat tttacatttg ataaacccaa ggaagaaagt caaagaatct tttttgtatg
    19981 taaaaaataa gatatttttg gatataaaag aaacttatta aaaataagca ttatataaaa
    20041 atataaaaaa tgcagtttta tagattaaaa ataaagtgat gatattttat gatttatgat
    20101 ttttaatagt tataaagttc tatagattaa aattagaata aaagaactat tacctagtaa
    20161 aattaaaata aaagagctat tacctacgat taagatagat aagtatttat agagtagaat
    20221 taagatagta atatagtaaa atgagataat taacgaaata tggaggaata ttgatgagag
    20281 attatgtact aagagcgaca tcaggaaatg ggcaagttag agcatttgtc gcaactacta
    20341 gaaatacagt agaggaagct agaagattac atgaaactac aaaagtagca acagcagcac
    20401 ttggaagaac attaacagcc acatctataa tgggattaat gatgaaaaat gatagtgata
    20461 aattgactgt aataataaag ggtggaggtc caattggaac tattatcgcc acatcagatt
    20521 ctaagggaat ggtaaaagga tatgtaggaa atccgcaagt agaggttgaa gactatccaa
    20581 atggaaagtt aaatgtagca gcagcagtag gtacagaagg tgttgtaaaa gttataaaag
    20641 acttaggtct tagagaacca tataatggga cttatccatt ggtaagtgga gaaattgcag
    20701 aagactttac ttattatttt gctgtatcag agcagactcc atcagtagta gctttaggtg
    20761 ttcttacaaa agaagatgaa gtagagtttg ctggaggatt tatagtgcaa ttaatgccag
    20821 atgcagaaga agagactatt gctaagttag aggaaaatgt agctaaatta ccttctataa
    20881 ctaacatgtt aaaagaagga aaatcaccag aggatatatt aaatattgtt ttagatggtt
    20941 tggagcccaa aatacttgat acctgtgaag ttgggtttat gtgtgaatgt tcaaaagaaa
    21001 gagtaaaaac tgctttggtt gcaatcggta aaaaatcatt ggctcaaata atagaagaag
    21061 ataaaaaagc agaagttggt tgccagttct gtaataagaa gtatatgtat actgaagaag
    21121 agttgcttga aattttaaag gaaatgtaga ctataaaaat aggtgcattg atatagtagt
    21181 atcatagtga catagtaatg tcttacttat ataggaatta aaatataatt tattaataat
    21241 agatatattt ctattaaaaa ataagtttaa taaattttta agcttaataa attttaagaa
    21301 ttgagaagct ttttagctgt aatatttgca atgttgcagt tagaaagctt ttttatttta
    21361 ttatagttcg tgtcaaagat tgtatgaaac aataaaatat tgtaaaataa tttgtatatt
    21421 taaacctagt tgccacaaag gtttataaga tatttgaatt gattatgcga aattctatga
    21481 agtagtaacc ctgtgacttt aatcatggga gattcagaag aaggagaaaa ttttaaatat
    21541 ggaaagcaaa actaagcaca taggaataag tatattaata ttattgatga tatttttaat
    21601 tgcaaagaat tttaatggaa aacttgaaat acctattcct gagagtaata gtagaaaatt
    21661 taaatcagca gcagtatttt atcctcaaca tcaggatgat gaggttttat ggggaggaag
    21721 tgctattgta gatgctataa aacagtgtgg tgttgataat gtatatgtgg tattagtatc
    21781 agatggttct ggagttaacg ttttcaaagc taacacaaaa tttagaaact taactaggaa
    21841 gcaaaaggag gaacttagaa ataacgagtt taaatcagct ttgagaaagc ttggagtgaa
    21901 acctcaaaat gtgattatac ttgcggatat agataaaaag gagggtacac attatgaatt
    21961 aatgaaaaag actatattgg attttgagca taaatttaaa ggtaatgtga cccatatagc
    22021 ccatcattat aagtatgatg accatataat gcatagaaag aatggggaag ttttaaagaa
    22081 acttaaacgt gaacacaaga taaaagatga cttatatttt attaagccaa aatacgtaaa
    22141 gtatatacca agaaatgaaa gagctatata taaggcaatg gagtttgatg actataacaa
    22201 ggttaagagt gcttgttatg aatataaggt tgtaaattca aagcgtaaaa tgtatggtat
    22261 aggatatatt tcggcacata gttattttga acatctttta aatgaccctg aacttacgtc
    22321 tgtattaagt gaagattaat ttcttataag tagtaagtta tgtttgataa gttgattaga
    22381 gttttctata gtttcgaagg tattgaaaat ttagttttat ttaaaaattt aaagatagag
    22441 gtttttaatg tctggtattt taaagttaag ttgaataatt gtatagaatt atttgtgaaa
    22501 gaagaaacag tgtaaaacat agtatcttat ttatggtttt aaaatcatag gtaagatact
    22561 ttttttatgt aactaatacc attttgtgat tgttaactta agagttttat ataatttaac
    22621 actcatatat aatgatgata tttatgtaga ataaatgcaa ttacgcttaa ataaaataac
    22681 tgtatttttt atagaaatca aaccctacac tatactacca gataaaatct acatgctata
    22741 atttgacctg tgtttataaa aaaaggagta atctaataaa atagtatttt atttatgtat
    22801 aactaacaac tattattacg atttactcta aagaatttaa agaaaaataa tgcaggaggt
    22861 agaatatgaa caatgaattt ataattttaa aaggatgcaa agagaataat ttaaacaata
    22921 tttccttaaa aataccaaaa agaaaaataa ctatatttac aggggtgtca ggttctggaa
    22981 aatcatctat tgtatttgag acaattgcaa aagaatcaca acgccaacta aatgaaaggt
    23041 ttagtacatt tgtaagaagt tttttaccaa aatatggaga ggttaaagct gattgtatag
    23101 aaaatctgtc aacaccaatt atcatagacc aaagtagact tggtggaaat tcaaggtcaa
    23161 ctctaggtac tattacagat gtaaattctt ttttaagagc tttatattca aggtttggta
    23221 gtgagtatat aggtaatgct aatatgtttt cttttaatga tattgatggt atgtgtccac
    23281 actgccatgg gcttggaaaa aagctagttc ctaatatgaa tcaaattctt gatatgaata
    23341 aatcattaaa tgaaggtgct atattgcttt cagggtttgg agtgggttct tggcattgga
    23401 atatattttc tgaatcaggt ttttttgata ttaataagag gatatgtgat tattcagaag
    23461 tagaattgga aaagtttttg catggtaaag cagaaaagat taagatagaa aatgctggtc
    23521 aaactaacat gacatatgag ggattaatgg ttaaatttaa tcgcctgtac ctaagtagag
    23581 agggagaaat atctgaagct actaagaaaa aattgagtaa acttcttata gaagataggt
    23641 gtcctatatg tgatggaaga agacttaatg aaagagtata taagtcttta attaatggtt
    23701 ataatatagc agatttaact agtatgcaaa ttgatgaatt ggttgaagtt attaaaagta
    23761 tagatgagcc agaagcacaa cctttaatta aaggaataat agaaaagtta aacagtatca
    23821 tagatatagg tcttggatat ttaacactgg atagagagac atcttctcta tcaggaggag
    23881 aatctcagcg tataaagatg gttaagtatt taaatagtaa tcttgttgat ttaatgtata
    23941 tttttgatga accaagtgta ggacttcatc caaaagatgt gtataaatta aataatcttt
    24001 taaaaaaatt gcgtgataaa gggaatacaa ttatagttgt tgaacatgac ccagatgtta
    24061 ttaagattgc agaccatatt gtagatgtag gaccaaaggc aggtaagtat ggtggagaag
    24121 ttgtgtatga aggcagttat gaaaatctac ttacaagtgg tacgttgaca gggaatgctt
    24181 taagtaaatt tcttcctatt aaagaaagtg taagagagca tagaggatat ttagaagtta
    24241 aaaattgtaa taaaaacaat ttaaaaaatg tatctattaa gatacctaaa ggcgtattga
    24301 ctctggttac tggagtagca ggagcaggta aaagtacgtt gattaaggat gaatttttaa
    24361 agcaaaatcc taatgctgta cttatagacc aaagccctgt ttcagcaaat tcaaggtcga
    24421 gtttggcaac atatagtgga attatgaaca acataagaag catattttca aaaacaaatg
    24481 gcgtaaatgc ttctttattc agttcaaatt cagaaggagc ttgtgataac tgtaagggtt
    24541 ctggaatagt agaaatgaat cttgctttta tggagagcat aaagagtact tgtaatattt
    24601 gtgaaggtaa aaaatttaaa aaagaagttt tagaatatag atttcaaggg aagaatataa
    24661 ttgaagttct tgaaatgtct gttttagatg caattgagtt ttttaattta aaacagatta
    24721 aaacgaaatt acaatgtatt gaaaaaatgg gtattggata ccttacttta ggacaaactc
    24781 ttgatacttt gtctggagga gagtgtcaaa gattaaagct tgctagtgaa ttaaataagg
    24841 aaagttcagt gtatatatta gatgaaccaa caacaggtct tcatatggct gatattgaga
    24901 attttatagg tataattgaa gaaattgtag ataatggaaa tacggtcata ataattgaac
    24961 acaatataga tgtaattaaa agagctgatt ggattattga gatgggacct gaaggaggaa
    25021 caaaaggtgg gagagtaata tttgaaggta ttccaaaaca attatgtaac aataaaatat
    25081 cattaacagc aaaatatata gtataataaa taaaatataa taaatttata atgatatttt
    25141 aataaatata atgggtgtat aaaatgataa ttaaacttaa cagtaataaa taatgtgaga
    25201 aatattcaaa tttaattaaa taaagtgtca gaaatttgtt taaattttag catttcaaca
    25261 gttctgacct tttttcttat ttttatggag aatatcgaga atggagtctc taatagttac
    25321 tttttttgtc tacttgcaag tttgattaaa aaatgtctat gcacacttgt gactttagtc
    25381 atggaaggct cagaatataa tcttaatata taatttgtga aataatttga ttacgatttg
    25441 ctgatgtata aacaataaag attaactaca ttaaaattta aatcttgtta agtaaaacat
    25501 ataaaaggag agagatgaat gataaatgat attctaacat tattatctga aagaagtgat
    25561 ttttttataa agctatccat agaacatttg atgatttcta ttatttctat aataattgcg
    25621 attgttttgg gtggtataat tggtattatt gtaagtgaat ttcataattc ttctaaacct
    25681 atattgggaa ctatcaattt tctatacacc attccatcta tttctatgct aggatttctg
    25741 ataccatttt ctggaatagg gaatactact gctgttattg cacttaccat ttatgcatta
    25801 ttacccatgg ttagaaatac atatactgga attaccaatg tggataaaaa tattcttgaa
    25861 gcagctagag gaatgggaag tacagatttt cagatattgt ataaaataaa acttccatta
    25921 gctctacctg ttattatgtc tggtattaga aatatggtaa ttatgacaat tgcattagct
    25981 ggtatcgctt catttatagg tgctggaggc ttaggtgtag ctatatatag aggaatcacg
    26041 acaaataaca cggtaatgac aattactgga agtatactta ttgctctatt agctttaata
    26101 tttgatttta ttttagggct ggtagaaaga ttttttcaac gaaaaagaaa aaagaaaaat
    26161 agaaaaaaag tttttgccat tctaggaagc cttattctta tagtaactat ctttacatct
    26221 tatttattta atccttcaaa gactcaaact attcacattg ccacaaaacc tatgactgaa
    26281 caatatattc ttggagagat gttggatatt ttaattgaaa aaaacacagg tctaaaagtg
    26341 gaaattacac aaggtgtagg aggaggaaca tctaatattc agccagctat ggaaaatgga
    26401 gaatttgata tttatccaga gtatacaggt acaggttgga atatggtact taagaaaaat
    26461 gaattatata ctgaaaatat gttcagtaaa ctacagtcag aatacaaaaa taaacttaaa
    26521 atgcaatgga ctggtatgta tggtttttct aatagctatg cattagcagt tagaaaagaa
    26581 gttgcagata aatataattt aaaaaatata tccgacttaa aagatgtatc ttctaaattg
    26641 acatttggag ctgaatatga cttttatgag agagaggacg gatatactcc attatgtaat
    26701 acatatggac tgaactttaa agatacagtt gatttagata ttggattaaa ataccaagct
    26761 atcaatgaag gtaagattga tgtaatgcct atatttacaa ctgatggtca gtatagtgtt
    26821 tcagatgtta tagttctaaa agatgataaa aatttctatc catcttatca atgtggaaat
    26881 gttgttcgtt tggaggtgtt agaggaaaat ccagagctat caaaggtatt taagatggtt
    26941 ggagatattt tgactgataa agaaatggct aaaatgaatt atgacgtaga aaacaacaat
    27001 ttagaaccta gagaagttgc tcgtgagttt ctgaataaga aaggtctttt ataaattgga
    27061 ggaaatgtaa tgacaactat tatacaattt aaaaatatta aaaaacaata taatgataaa
    27121 actataatag ataatcttaa tttagatata gaaaaaggag agtttttgac tgtcattggt
    27181 tcgtctggtt ctggtaagac aacactctta aaaatgatta atggtttgat tttgccagat
    27241 ggaggaaata ttttgataaa ccaaacagat atcaaaaacg aggatttaat taaattaaga
    27301 agaagaatag ggtactgtgt acagggaagt gttctttttc ctcatatgac tgttgaagaa
    27361 aatatttcat atgtaccaaa tcttctaagt aaaaaaaata aattagaagt aaaaagagct
    27421 gtagacaaat ggatggaaat agtgggattg ccaaatgata tgaaagtacg ttacccatca
    27481 gaattgtcag gtggtcaaca acaacgtgta gggattgcaa gagccttagc ttcttctcca
    27541 gaaattttat taatggatga accttttggt gcagttgatg agattacacg aaagcaatta
    27601 caaaaagaga taaaagaaat tcataaaaaa acaggagtta cgattatctt tattacacat
    27661 gatatttatg aggctttgat tttgggaaca aagactttgg tattaaatca tggagttgtt
    27721 caacagtatg atactcctga gaatatttta aatgctcctg ctaatcaatt tgtagaccag
    27781 ttattgaata taagaaaatc tataatagat gatgagaatt taaaaaaata aatttaaatt
    27841 taaaatcaaa ttgttgtgat aaaagctatt gacctagagt taacttcaag ttgtatattg
    27901 gtactaaata atagatttaa ttttgcaaag gataaggtgt tttaataaaa atgaatgtag
    27961 aaaacgaatt acttaaaaac ttagatagat tgcatacaac agagttaggt gttgtaagaa
    28021 ttaagaaaaa tctttctttg gatacaaatg atgtagtgaa ctggtgtaaa actaaaatag
    28081 aatctccaaa tgccattatt aatagaaagg gaaaaaactg gtatataagt atatatgatt
    28141 gtattataac ggtaaatgct cacagttata caatcattac agctcataaa gaaaagaaat
    28201 gaaatgaatt gcaaaataca aaggtcaaga gcattttcca ttgtttgtag tacctatgaa
    28261 gaagtatata aaataatatt acttttgagt aataatttaa attttggaga ttgaaaaatt
    28321 gaatatactg atttacatca gtaccttgtt ggagcgactt ggattttaca aaaagaatat
    28381 gataaatatt agactagata atcaatgttg tagtgaatta ttccatgtct agtgaatata
    28441 aataacataa aaaaccgtca agatgaatag tttattcgtg cttgacggtt tttagtattt
    28501 gttgaagtaa aattttattt ctttagtata tcacttttag tcaaaccatt tgatttagct
    28561 tgagtattcc actgatgatt acctataagt ttatatagga atctaggaaa attaggtgaa
    28621 ataaaaatat tatttttctt ggaattacct atatttatat tattactaag tatatttttt
    28681 gaaagttctt ttaatgcaat tcctaaatct tttttttgac ctttacccaa aggtacagat
    28741 tctagtgaac caaacatctc accagctcca attccaatac cttgaatcca tgtaaagttg
    28801 atttttttac accaatgctc tatcatttga attgccaaat gattatgttc accttcattg
    28861 aatccacagt taactattgc atacactgga ataggttttt tattttgtgt ttttaaaaat
    28921 ttttcacatt cctctaaaaa atgaagtaaa tgagatggaa tagcatctac ataaagagga
    28981 aatgcgatta ttaatctatc acaattaagt atggcattaa gagcatcagg atacttagat
    29041 gtgttatcta ctttaaatgt aaaaacttta ttgtcatttt gaataagttg ttttacttcg
    29101 gataaaaaat actgtgaatt atttttattt acttttggac taccatttat cattactata
    29161 ttcatatgga ctcacctctt atatcttgta tattttcata gaaacaaaca gagtgttctt
    29221 ttatattgaa atttatagca tttccattta ctaatttcgt agcagtttct ttttcagatt
    29281 ctgtaataca atttccatag aatatagctt ctaaatttat atgtttgtcg tatctacttt
    29341 tatgacgcat catattatct tttatcacaa agtatggaag aatataatta atacttttat
    29401 caagtacgtt tttgacaaaa gggctaaacc ctccgtaaca gcatctgctt attataataa
    29461 ttccatcaga ttcatttata agtttaccca tgttgctgta ataatctttt acaacacact
    29521 cagtaggagt tttaatccag caaccaaaac aacctataca tttgtggatt tcttttgtgt
    29581 ttggaagtat ttttatattg tcatcaagtt tgggtaatag cttttctaat tcttcatcag
    29641 ttaaatcgtg tattaaaagc ttcataaaat ccatctcctt ttattatgta tgtttacttc
    29701 taaaaatcat atcttataaa tttttcagta aatctttaca ccaattaatt acaaaattat
    29761 aatagtcaac tccataaatc attgtggcat acatatatgt atattggtca acacaatgat
    29821 tttcttctac atcaattttt tgtttactta atttatttag aagtaattct acttcagtta
    29881 ttagcatttt taagtttgtt tcaattattt ctttgggtag atacttgtaa aagaatatat
    29941 taacaaggtg gttttgcttt gttttagaaa aatttatagg tttctttaac cactcaagaa
    30001 atacttcttt accagtatta gttatggagt atagtttttt taatttgcta ccatctataa
    30061 cttcgtgata gtgtatatat ccttttgttt ctaatctttt aagtgcagga tagatactgc
    30121 caaagctagc gtcaaaaaag tacgaggtac tctctgacat tatttgtttt aagtcgtatc
    30181 cacttaattc tttttccatt aaaaatccta aaataatgta ttctaacatg ttgcctccta
    30241 gtatcaatta gatatatatc aattcgatat atttattatt gcagataata aatattacgt
    30301 caagatgctt tttaaaataa gctaaaaaga attagaaatt attaataaag atgtaaaaaa
    30361 attaatataa aaggtaatta aatatcaatg aagatttaaa aatagttaaa tcaaagtaag
    30421 agtctaatat ataaaattta tagtaacttt atggtttaaa tataaacctg tgtgctattg
    30481 acaaagtata aaattagcag taaaatgatt gcatgagcaa atagattatt gcgaacgcaa
    30541 aaagataagg acaatagata ttaaaggaga gaatatgaga gagctattaa aatgggtttc
    30601 cattataaat agatacaata caaattatat tgacaggaaa ttggcggata ttggaatcaa
    30661 caatagccaa tatttttatg tattacacat atgtaataat ccaggtatta cacaggatac
    30721 tatatttgag aaaattcttg tgaatcctag taatataaca agagctttgg caaatttaga
    30781 aaaagaaggt tttataacaa gagaaccagg tgtaaaggat aaaagaacat ggcatttata
    30841 tcctacagaa aaatctttag aatgttatga tgaaatacta aaaataacaa atgggtatgt
    30901 tgaggagttg ttgagttcat ttgagaaaga agagcaagag ttgtttatgt caatgttaaa
    30961 aaaagttgca tttttggcta ttgatatgaa tgaagaagca aaattggagg cgaaggaaaa
    31021 tggaagaaaa atataaggag ccattggaat atgaaaaagt ttcaaagtta ttaaccaagt
    31081 acgcaattcc tagtattata gcaatgttag taagtgcttt atataacatt gttgaccaaa
    31141 tatttattgg gcaaggtgtt ggtgtattgg gtaatgctgc tacaaatgtc acttttccgc
    31201 taacaacaat atgtactgca attgcattat tgttaggaat tggaggagcg tctaagtgtt
    31261 cattggaatt aggtgctaaa aattcagaaa aagctacaaa agcagcagga aattctatat
    31321 gcttgatggc tgtttttgga ataagtttat ttataatagt atcaatattt ttaacaccac
    31381 tattaaaatt ctttggctct acatcagaaa tactacctta tgcacacaca tatacaaaaa
    31441 ttacatcaat tggattacca tttcttataa tgtccactgg aatgagtaag ttgatacttg
    31501 cagatggaag accaaaagct tctatgtttt gtatgttaat aggagcagtt attaatacaa
    31561 ttttgaatcc attattcatt tttgttttta atatgggaat tgctgggtct gctttagcaa
    31621 ctgttattgg gcaacttata tcttttggaa ttagtgttca ttatataaag aattttcaac
    31681 atattaaatt acataagaaa agttttaaat tagatagtat aatttataaa catatatttg
    31741 cactaggttc aagttcatgt tttaaccaat tagcaatgac tgtaacacag atagttatga
    31801 ataatacatt ggcttattat ggggctaggt cagtttatgg aagtgagatt ccacttgcct
    31861 gtgttggtat cattattaaa gtaaatatga tttttatatc tataattatt ggtatatcac
    31921 aaggtatgca accaattata gggtataatt atggggctga aaagtataat cgtgtaaaag
    31981 aagcgtataa gtttgcagtg ggaagtgcaa ctattatatc tgttattgca ttcttatgtt
    32041 tccaattttt cccaagacaa attacgtcta tatttggtaa cggaaacgag acttatttta
    32101 tatttgcaga acattatttt agaactttct tgttcttaac atttataaat ggtgttcaaa
    32161 tagtatcatc aactttcttt acatcaattg gtaaatcagt gttgggactt tttacttctt
    32221 tgactcgtca aattttattt ttaattccat tgatagtgat tttaccaatg tttatgggga
    32281 ttgatggagt aatgtttgca ggaccaatag cagatgcagc ggcggcaatg gtatgtatat
    32341 actttgcagt tcatgaaatg aaatcattga ctataaagca aaataatttg atgagtaacc
    32401 ataataagat tgcagaggta taagacaata tttaagaagt atagaaaatt aatttaagaa
    32461 gtataataag ctaatttaaa gaagtataat gagctaactt aagaaatata gaaaattaat
    32521 ttaaagaaat ataataaatt aatttaggaa atatagaaaa ttaatctaaa gaagtataat
    32581 aaactaattt aagaaacata gaaaattaat ttaaagaaat acaataaatt aacttttaag
    32641 taacattaaa ttaatgtaag taaaataacg ttcatgtgaa gatttaaagg tgcattttct
    32701 ggagctaagt atatgttgta gagtgtatat ctctctagtc tgtgaagttt aatagctcaa
    32761 gaaaatgcac tatttatgat gcttattttg ttttatttcc aattttagaa ataactattc
    32821 taattaaatc taaaattata ccataaataa gaaaagaaag tatagatgct atgtaccaat
    32881 aaatcgaaat tgaccctgta attgttctac atgggatttg catacctgaa tccataaaaa
    32941 taaaaaaact atcaattctg gaaataatag acaaaatagg attgaaacct attagaataa
    33001 tactttttga gtcttgacca atttgatgca tagaaatctc aaacaatgca attaaaaaaa
    33061 accaaaatgt aaaagattta ataatttttt tcatcaaaat acctcaccta atataaattc
    33121 tgtttgcact atttgcttac tataactatt tatctccatt cagttacatc atttaattgt
    33181 aatctaggtc ttcttgatgg ttcttcatca ggatacccca aagatattgc tgccactaat
    33241 tgactatctg tattcaacca ttcacataat tcacgatatg caaagtatac atcacaaatc
    33301 caaagactac ctagacctaa ttccacggct ttaagcgaca tattttgaat tgaagctcca
    33361 attgattgaa tgtttgccat ttcatagaat cgttcttcag gggatagatt ttctaaaagt
    33421 gacttaccta gtatatttaa aataaaaatt gttactggag cttgtttcat gatttcaacc
    33481 gtgtaatttg caccagagat atgttgacga cttcctggaa gaagcccatt atcatcaatt
    33541 tcgttttgaa tacctttgct catggcttta agcatagatt ctttttcctt ttcagtgatg
    33601 acaacaaaac gccatggttg cctgttttta gatgaaggtg catttattcc agcttcaatt
    33661 attttctcta tagtttcatg tgaaatgctt tgatttttat attttctgat acttcgtctt
    33721 tttgatatag aatcacttat cattttaagt aacctccgtt tattttttgg aaaaatatat
    33781 ttgttttcta tttttaatta ttttagcatt aatcagaaaa aaagtcattg attttagtat
    33841 acaattatta atgattgtat taagaattgc atcaaaaagt atgtgattat actaagggat
    33901 tatattagac attatattta aaattgtatt aaaggttgta tttaatatta tattaagatt
    33961 tatattatat tgggtcttat attaaattaa ggattataaa ttgaaaataa gctataaaaa
    34021 ctcaatattg ttttgttcag agataaaaaa agaatgcctt aggtgatttt tattaaaaat
    34081 taagagtgat aagattatat actttataaa tgtaaatatg acgaataaaa atgataaata
    34141 taataatcta tatatttaca ttaggagttt tctatactat aattatttaa aactaaatat
    34201 aaatgttgga attatttagg acttgaaatt gtttaaaaat aaatataagt gatgaagagg
    34261 tgatgtgatg agattagata tggatagtat gttatatgta ctaatttata tgacattatt
    34321 ggtatctgtc attggaagta tattttattt ttgtaaagac ctcttaaatc ataaaattaa
    34381 gtatgtttta ataaaaaaca tatttgtaaa tagaactaca tattctgaag aaaggttgcc
    34441 taaacagtat atagtttttc agaaatatga tatttggagg tattgtagtt tgttttagtt
    34501 tgaaatgaat ctattataaa ttctaaagtt taaaaataaa agggagagaa taaaatggat
    34561 ttcatttcaa gtatattgca aggattatta agtatattat ttaattttac aggtgatttt
    34621 gggatttcta tagtacttat aactttaata gttaaattag tacttatgcc actatcatta
    34681 aaacaaagat tttctgtaaa aaaacagcaa gaattagctg aaaaaatgga acatataaaa
    34741 gaaaagtata agaatgatac taaagaactg gaaaagcaaa tacaagtaaa ttctgtagaa
    34801 agtatgaaga gtatgctggg atgtcttata gttttagtac aaatgccagt agtatatgct
    34861 ttatatcatg tatgtttaga tatgacaaag gaatttacaa caattataat tccatggatt
    34921 gctaatttag gtacatttga caatttgttt atattacctt gtatatatac gttaattatg
    34981 ttagcttcaa atttagtgaa ttatataccg tacttaaaaa taaattctca ggtaaagttt
    35041 aacaaacaaa tggctatggt gactactata acaagtctta tactgactgt tagaactcca
    35101 gtagccatag gtctgtactt tataacaagt gcaatttatt cattaattga agatatttgt
    35161 tttagaatat attttaatcg aaaaaataga attgtgacaa aataatataa ttattattag
    35221 aaatatttta gcctgctaac ataggaaaag ttagtaggct atttttatct atgatatcaa
    35281 ttccattaag aatagtctaa aaaatactat caaaatacta tccaaatact ataaaaaaat
    35341 agttgaaaaa taaataaatt aatataaact aaaataaagc ctacaaaaaa gaggtgataa
    35401 atagaaatgg ctaaaatact agttgtagaa gatgaaaaaa ggatgcaaag tattattgta
    35461 gaatatatgc aaaagggagg atatacttgt gtaactgctg atgatggagt cgaggcactt
    35521 acaatattaa agagcaacaa tatagattta atgatattgg atgttatgat gccgtattta
    35581 gatggatttt cagtgtgtag agtttcacgt gaaatgacta atatacccat tattatattg
    35641 acagctaaag gtgaagagga ggacaaatta aagggttatg aatatggtgc agatgattat
    35701 ataacaaaac catttagccc aaaagtactt ttagcaaaag ttaatgcctt gttacgtaga
    35761 tatactactg gcattccaaa aaattcattg attttaggaa agatttttat tatggtagca
    35821 tcaaggcaag tatatgtaga agataaattg attgatttaa catataaaga atttgaatta
    35881 ttgcgtttat ttatggagaa tccaaatcaa gttttttcca gagagaaact tttaaattgt
    35941 atatggggat atgattttga aggaaacaca cgaactgtag atacacatat aaagacctta
    36001 cgcaaaaagc ttggtagtga agggcatcat atagttacat taattcgttc aggatataag
    36061 tttgaggtta aggaatgagt agtttaagaa agattataga aaaattgaaa aatttagata
    36121 tttcaaattg gattaaacaa aattttggac tacattcagt tagaaaaaaa gtgtttttac
    36181 tttctaaatt atcaggggcg ttaatcatac tattttatct ggttgttgaa gaactttcga
    36241 taaactctaa atttgaattt tggatttggt ttataatact ggttatattt attatgagta
    36301 ttgatttttt attgggaaaa tttatttcag aaccaatcac atccataaat aaatctgcaa
    36361 aaagcatgtc tcaacttgat ttttctaatc catgtactgt aaatactaat gatgaatttg
    36421 gagaactttc taggagcttg aatacaatgt ctacaaatct acaacaggca ttatcagacc
    36481 tagaaagtgc aaatattcaa cttgaaaagg atgtaaataa ggaaagaatg ctattggaac
    36541 aaagaaagga gttggtagat acaatttcac atgaaatgaa gactccactt ggcattatac
    36601 gtgcgtatac agaggggctt atggatgaag ctgatgaaga aaaaaagaaa aattatatga
    36661 atgttataat agaagaaact gatagaatga acaatatgat tgtatcatta ttagacttat
    36721 ctgcattgga agcaggagtt tctaaactta acccagagcg ttttgatttt atagagtttg
    36781 ttgaaactgt ggcaggtcgt cttttaattg atataccaga tgccaacttt tattttacat
    36841 atgatttgcc agagtatgaa gtttttgtag tggtagataa aatgagaatg gaacaagtag
    36901 tagagaatct aattattaat gcaaagaagc atgttgtata taatggtaat ttagatttat
    36961 cgattacatg tgaaaatggc ttgattttat ttgaaattta taatgatggt aggattatag
    37021 agcaagatga gatttcaaag atttggtcta agttttatcg tagtgttcaa tctcagcgta
    37081 caggaggttc aggtctaggg cttgcaattg tttcacaaat acttacaatg caagggttag
    37141 aatatggagt gaagaatcgt gatagaggag tagagtttta ttttatgatt ccaattgatg
    37201 aataatttag tattaattta taaattataa gtatttgatg taaaatattt ttctttgtag
    37261 acaatagata tctaaagaga ataaaataaa aaaatttaat gaaaaaagct taatgaaaaa
    37321 gtctaataaa aaaatttaat aaaaaaattt aataaaaagc ttaatgagaa gtcttgtttt
    37381 cctgatgaaa acaagatttt ttattaagct ttttattatt tcaccttgat ttcacaagag
    37441 agacactttg atttcaccaa atagaaataa aataagttaa ataaattaaa aaatagaaac
    37501 gtaattaaat aagcttacaa gggggagtac ttatgaaatg gtatacatgg ttgactatta
    37561 tattgatagt attggtttct attccgctta aaattaaatt tataaaatgg tgggacagac
    37621 gacaaaaaaa atgataaagg aggttatgat agatgataaa agtagaagag ttgaaatttt
    37681 cttatggaaa agataaacag atattacatg gacttaattt tgaagtaaaa gaaggagaaa
    37741 tatttggatt tcttggacct aatggttcag gaaaatccac aacacaaaaa atcttaaatg
    37801 gtgttttaaa aggttacaat ggtcacgtat ccatttttgg taatgaagtt aaagcataca
    37861 cagaatcttt atatcaaaag attggtgttc tatttgaatt tccttattta tataccaatt
    37921 taagtgcaat tgataattta gaatattttt cgtcttttta tcctaaaaat caaaggagag
    37981 acatatatga actcttagat ttgttagagt ttaagaaaga gtttataaat aagcctgtat
    38041 catcctattc aaaaggtatg aagcaacgta ttagcatggc aagagcattg gtaagtaatc
    38101 caaagttgtt gtttttagat gagcctacta gtggacttga cccatctgga gctgtactat
    38161 ttcgtaagat tattgaagaa gaacgaaaaa aaggaacaac tatctttttg actactcata
    38221 atatgctaga tgcagattta atgtgtaaca atgtggcttt tattgcagat ggcaagatta
    38281 tggcaataga taaacccaaa aatttaaaaa tgaaaaatag caataataaa gttgaagtgg
    38341 aatttgtata taatggaagt cgagatatta aaattgtaga tataggagaa ttagaatctg
    38401 gaataacttt taaatatgac gaaatcttaa gtgtacattc aaaagaagct acactagaag
    38461 aagtttttat taaatataca ggaaggatgt tagtgtaatg tattctaaat tttttacctt
    38521 agtaaaaaag gatttttgga tgatgattta tggtaaattt tttgtactaa cacttggctc
    38581 tcttatactt tattcatgtt atattaattt tggttatgta aagtttatgg atgaagatag
    38641 ttatcacaat aatgtatatc tatataatcc agagaatata agcatgagta catctccatt
    38701 aattaatcaa gtttcttcta taggtgaatt aaaagcaaaa cttgatgaag atacaagtgc
    38761 agtttgtatt gatatgagct ccagtaagcc gaaagtaatt ttacatgaga gtattaaagg
    38821 cgttgacaat tatagagctg actatgcatt gtcattatta tcatcagaaa aagaccataa
    38881 tagcaaaata tcggacaaca atgcaataat tcaaattaat gataaggata catctgagat
    38941 aaaacaaaga aaagaaatga cttgtgagat tttattcttt gaaattgtag ctattggatt
    39001 tttagggatt gcctctttat tatttaaaga aaagcagatg ggggtaatgc gtattactgg
    39061 tattttacct gtaaaaagaa gcctttttat attatcaaag atatttgctt ttttgatatg
    39121 tgacctatgt tttacagtgc ttttagtagt atttaatgtt ggattttttg aaggaataaa
    39181 aatactttca caagtattag ttcaagctag cattttatca attattatgt ctttgattgg
    39241 atttggatgt tcaatgttat tgagagattt taagcaattt tctcttatat atcttgtggt
    39301 tgctgtattt ataactacac ctatatttct atctgcaaat acatcttttg aaatagattg
    39361 gattaaatat catcctttct accatgttta tatccagctt aaaaatgcgt ttttcatgaa
    39421 tttttcaaat gaattaatct attttgtagt gtgttccttg acaataatag ttctattttt
    39481 acttgtaaaa aatattttta ataaagagtt ggttagggag ggataatctt gataggatta
    39541 cgttatcagt tgaagagtat aagaaaagat aaaatgtgta taatttcatt ctttttacca
    39601 gttgtcatgg cgattttaat aaattttatg ggaacaattg atatgtcttc attaggagag
    39661 atacattttg gtatagtaaa ggatacactt cctgtacgaa cagagcaatg gttgaagaag
    39721 tatggtgtgt taagtgtata tgacacaaaa atgcatctaa tacgtgaaat taaggatatt
    39781 aaaacggata caattggagt tgttagagat ggtaaaggga taaaaactgt gctttatgga
    39841 aatgagatta atgctataaa aaatgttgga aagacattgc cagagatgtt tagactaaag
    39901 ggagatttaa aagatgttga ggttacaata ttgcctaaag atagtatttt aaaagagttt
    39961 caaaatgttt ttattgctat gattttaatt actgctatgt ttatgggatg cacctttaat
    40021 gcaatgaata ttatatctga aaaagaagat ggaatatcat ttataaatga aattttacca
    40081 cagagtagaa gtcagtatat tatacaaaaa gtatttttgg gtcttttatg tgggtgtcta
    40141 tcttcaatga taactgtatt tatatgtttg gatatttcaa tattagatat gataatgatg
    40201 ttactactcg ttgtattttc agcatttatt tcatcactta taggtttatt tattggaaag
    40261 ttgtcagaag gtcttatggt aggaattgtt tatattaaaa tagtaatgat tttatttata
    40321 ggtgttcctt tgttaatata tcttctaggg gttaatacaa gcggtatagg gaatttatgc
    40381 tatataatgc cgtcagttgc tacatttaat ggtattatgg agattattaa tggtaatgtc
    40441 attattataa aagatattgt aattttggct gtacattgtg tagtatggtt tatgctgtat
    40501 attattttag ataaaaaaag aaagttatct tttagtagat aactcaatat aattataatt
    40561 agaacaattt aataggtgat ttaatatact ttgtatagtg taatttatgt agtacaattt
    40621 gtatacttta atttatgtag tgtaatagtt agttttattt tataattatt caatataatt
    40681 tagtaagaag ttcagtacaa ttagagctac ttagtggaaa atttaatagg tacttaaact
    40741 atataaatac tttattttcc tccatttgta ctataaattt aattgatgat ataaatggag
    40801 gtattattat atgatttgat aaatttcatc attataactt acaagtaaat gtattattat
    40861 atgagatatt attatataaa gttaataaag atagtatcaa aatattattt gttataaaga
    40921 gaggggctca aaataaagat aaacctattt ttcaatgttg aaatgataaa aacatatttg
    40981 attttatata aaaaattttc ttcatgaatt aaaaagtcca ttttgagacc cctcattttt
    41041 aaccagataa atcgagttaa actatttaaa tatattactc ggattcattt gacttagata
    41101 ttccttgctt gtaaaattgt tttgagtagg gaatagccaa agcaaaaaat aaaagtataa
    41161 tccctgctac gattattaaa ttattaatag acattacatc tgccattggg ccgaaaatca
    41221 tcataccaag aggaataaaa ccagtatata taataatagg taagctaaga actcgaccta
    41281 gcatttgtgg tgctacatgc tcttgcaaca tagtcatagc tgatgcttga atgattggaa
    41341 ttgaaaaatt cgtaaaaaac ataaatataa aaaattgcca cgcttgtgtt acaagaccta
    41401 gaataattga aaaaatagca taagataata ttgctagaaa aaaggtctta tttctatttt
    41461 taaaaccacc aaaaactcct ataatcaatc cacctaaaac catacctaaa aatccaatca
    41521 tttcaataat agacaggtat atataaccct tgccaaatgt tcgttcaata agaagtccta
    41581 taagaaatcc tgatggaaca caaagaagca tgaatgctcc ataagtgaaa agcacttttc
    41641 taatgaactt atctgaaaaa cagtacttta tccctgatac catatctgca aaaaatgaga
    41701 ctttttcagt ttgttttggt atatcatgtt taggaatttt gataaatatc aataatacaa
    41761 tagcaataat tgcagtaaat acatcaatta aaagaacttg atttatttta ttaccaaatc
    41821 caaggattgc agcagccaca ataggaacta taaattgtac tatagactgt aggctaccat
    41881 ttataccatt aaaacgcatt aaatgttctt ctggtacaag ttgaggaatc attgcgttta
    41941 cagcaggtgt ttgtacacca cttcctagtg aacgtataac agatattact gatatggcta
    42001 ttaattcact tgttgttcca tttgatgaca tcataaatag aattagaact aatgtagata
    42061 tagcaattgt tgaatctgat acaattatga gtacctttcg attgtagtag tctgcccata
    42121 caccagcaaa aaaagaaatt atcatttgag gtataaagga gcatatagtt aaaactgtta
    42181 cccatacacc tgatgatgtc tgaagtgtga cataccatat cattgccatc tgtacaagtg
    42241 atgagccaaa taaggaaata tattgacttg ctagaaaaag aatgactctt ttcttccatg
    42301 tagaattaat atttttgttt tccatcctat tcctcctttg atttgtgtgt ttaatttttc
    42361 tcgctcttaa ggataacaca caaatcaaag tctggagtta gagtggaggg ctaggaaaat
    42421 tgttttttca taatttgaag atgagatttc attgtttttg cattatgttc agcttctttc
    42481 aatgaagtta tcagtttgtc acacactgag ataatttcgt catcatcttt tggagtgtca
    42541 aggacagttt taatattggt attaggatta gaagataaag cattgagcat tcgtaaaata
    42601 gctgaaagag aatagtttgc acaacgaagt gcacttataa ttttaagtcg ttttatatcc
    42661 tcatcagtat atacacgata accattttgt tttcttttta cttttaacaa accattcatt
    42721 tcccaatttc ttaaagtatc tattgtaaca tttaagtgtt ctgcagtttc ttttctagtt
    42781 aaaaagagtt tatctgtttc tggagtatgt ccatttaaaa tctgtgtaac aatagtaagt
    42841 gcttcctcgg cattagattt ttctatttct aattgtttca aatattgatt tacaagacaa
    42901 atagccttgt caaaatctct atttgctgat gttcttacaa tctcaagggc atcttttctt
    42961 aatcctcttt gtaccacttc aattttcaag gctgtacgag caaatctaaa ttgttctata
    43021 tgaaaatcat taaagatacg ataaccattg gtattacgct taggtttagg tattaagctt
    43081 agctcttcat ataaacgtac tgtattagga tgtacaccaa ttaaatctgc tacctctgat
    43141 gtcgtgtaag tgtccattag tattcaactc cttttagata tatagtatta gtcataataa
    43201 catcaaacaa aagtctggtg ttatagtgga gggtttggtt atctaagagt aattagtcta
    43261 tttaagatta attactctat tatagaagta agtatatact tttcaataaa ctcccatcta
    43321 tcacgaggtt taaacactat tttagatggt atggctatta ctaagtcata ttgtggaata
    43381 caacaaatag catttcctcc agctcccatt gctgaatacc acaaaactcc atctttttta
    43441 catagccacc acagataacc gtattcatta ctattcattt taactgattc ttcaatccac
    43501 gatttagata taatacgttt attattccaa ataccatcat ttaaatacag aaaaccaaat
    43561 cgcaacatat ctctagcact caatgtaagt ccccagccac ctgtagaata gccctgtcta
    43621 tcttttgccc aacccttaag attttttcca aagaaatctt caaaaccaaa atctttcata
    43681 tcataatctg gtataatttt cataccaata ggtttaaata agtattcatt agcaaattca
    43741 cgagcagatt ttcccgtagt ttttgttata atagctgaaa gtaggtgtgt tccagctgaa
    43801 gaatatttga aagtaccaat ttcacctttt tgaccaagct gattcaaggt atattttatc
    43861 caatcttttt gtttgcaaag tctctctaaa gactcagtca tatttttaaa agggtatggt
    43921 gcagtcattg taagtaggtg acgtatagtt actgcttttt tacatatttc agaaggacta
    43981 caagtatatt cagggaaaaa atcaacaacc ttttggtcaa catcttttat atatccttta
    44041 tctattgcaa tgcctattaa agctgatata atactttttg taactgatgc aacatgaaaa
    44101 gtatcgtcag cattatatcc attgtagtat ttttcaaaga caacttttcc ttttcttgca
    44161 ataattattc catttatatt gctatattgt gagattatta aaggttcaag ttgtgaaagc
    44221 ttttctgaac tcataccaac acttgaaggg tctacttttt caaaaattaa gtctaagcaa
    44281 ttgtttttat tcattaaaga taccttcctg ttatagattt tggattttct tttagagttt
    44341 ttggagaacc ttctgcaatt atataacctc ctttgtcgcc accttctgga ccaagttcaa
    44401 caatccagtc acaaacattt aatacatcta tatcatgttc aacaacaatt acagaatttc
    44461 catttgctac tagttcatcc aacaattgaa tcagcttagc agtatcatat agacttagac
    44521 cagtagttgg ttcatctaat acataaagaa tattaccatt tcgtttttta ccaatttctt
    44581 ttgcaagctt gactctttgg gattccccac cacttaaagt tggtgtaggt tgacctaatt
    44641 ttatatatcc catacctatt tgttctaaca catttaagtg tgaaacaata tttggaatat
    44701 ctttgaaaaa atttacagcc tcagagatac tcatatttaa aatatcatga atagttttat
    44761 ttttatattt aatagataag gattcatcat taaatctttt tccatgacag tcactgcata
    44821 tatggtctat acttagatta tttcctaacc agactttttc atatccgcta ccactacatt
    44881 taggacaagc ccctttggag ttaaatgaga aatgaccagc tgtaaatcct cgctctaacg
    44941 attctggctg acctgcaaat agtgtacgta tcttatccca tataccaata taagaagcag
    45001 gagttgagtt catatttttt ccaataggag attgagatat ttctgaatat ccagaaatat
    45061 acttagtacc aatcaatcta tctgcaatag tttcgacaac tgcataatca tcttcatcac
    45121 ctatttcact ctctgaagaa tttgtttgat tattgatagt atggttatta aattgacttc
    45181 taagaagagg aagtaaggtg tctgatataa gtgaactctt tccactacct gatttgccag
    45241 atattccaac catagcaccc aaaggtaatg atactgttac atttttaagg ttatttgtat
    45301 ttgcattttg aacagttata cagggtattt catcaatatg tgtaatattt ttagtgcttg
    45361 ttctattagg cattgaatat tttccagata gatattgtcc agtaagtgat ttattggatt
    45421 gaagtagacc ttccaaattt ccttgatata ctaattgccc accttcaata ccagcttttg
    45481 gcccaatatc aataatatgt tctgccatct caattgtgtt tttatcatgc tcaactacta
    45541 taactgtatt gcctaaatct ttaagtttct ttatggattt taagatgtct attttttctg
    45601 actcatgcaa tccagcagtt ggttcatcaa gcacataaat taatgaatcc atctctgaat
    45661 caaggtgtga atttaaaaat agtctttgca tttccccacc actcaaagtt gatatttctc
    45721 tgtataagga tagatgacct aatcgtgatt ctattagatg tcgagttttg gacaaaatat
    45781 tatttacaag gtttgtacca aatgtgctta aattaccttg gtctaataag attttaagga
    45841 actcatcaat ttctagaatc gtcatttttc caagttctcc aatatgtttt ccgtttaaaa
    45901 gtactctacg tgcttcttca ccaattttaa aaccattgca atctgaacag gcagtcatag
    45961 tataaactcc atttaaatct tcgcctcttt tgtaacgatt gtgaaatacc tttgataaag
    46021 aggaactttt tttgccattt tcataatgac catagagcac ttcatttttt acttcttcag
    46081 gtaattgtaa gaattgtatg tctaaataat cgttgaattt tttagagaat actctcaaat
    46141 atcctggtgt aatctttgct ctatctaaga cttgttttag ggtatcatgc ttatcaagga
    46201 ctaatttttc aatattaatc tcaaaatatg caccatgccc agaacatttc atacacattc
    46261 catctgaaga gttgtatgag aaataacttg gctttaatcg ttcttcttca tacccacaat
    46321 tattgcaaat taaattatcg cttacaggag tatcacacat agtacacatt atttgacctt
    46381 ctactgaata caatagtgta agcatgttga gaatattggt tcttgtgcct actgttgaac
    46441 gaggattact ttggcgaata atattttgtt gaacagctat agtgggagct aaaccttgaa
    46501 tattatcgaa cttatcctca ctatcaatac ctgcaagtat acctaaagat tgaaggtatt
    46561 gtttacgtcc ttcctcaaat acaatgtcaa acataaggct agatttacct gagccactga
    46621 cacctgttgc aacaaccagc ttatctttgg gaatagaaac atctatattt ttaagattgt
    46681 gtatctttgc tccattaatt tttatttctt tcattggttc acctcatttt atcaatttta
    46741 tcaaaccata aaatagggat atattaatcc ttaatacaag aatagattag gtgaggttat
    46801 taaaaaggtt ctataggtaa atatatatcg accaagtgtc tattttgagg gtgattgtgt
    46861 gggttgttaa gatatacttc aaaagggaag gaagcacgta gcttataatt aacatttgat
    46921 aaccattcat tatacataaa atcccacgca tcactatatt cagattttga aatatcaaaa
    46981 tgtcctacaa gatattttcc agaaggtatt atcatattgc caagattgtc attctctttg
    47041 acaacaatgt tatctggaat ggtcatgcaa atactagtcc ttaattgatg ttcctgtgta
    47101 aattgtggat tatcatgata aattgctaat atttgtgtgt tttcaagtcc aagtagattc
    47161 tgctcacttg catatgtgaa taacctttct aaaagttttg ggaaagtact agttagatta
    47221 ccatatgaac cagtatatct agtgtaaata gtattcatat tatcaagttc tagaatttca
    47281 atttcacctt taacctctct agtattctta catttaggtt ttgatatgct tctattgtac
    47341 tgagaaattt tatatggttc tttgcaattc ttgctataat tatttctata ttttatagga
    47401 cttattttat agtaattttt aaatgctctc gagaaaactg ctgaatcagt aaagccgaag
    47461 tagtgtgcaa tatcagtaat ggtcatgtca gttcgatgaa taagaaaagc agttgcattc
    47521 tctagtttta gcctatttac atactgtgcc aaagtttctt tttctattgc tttgaagatt
    47581 ctatgaaaat gaaactttga aaaacctgct atattagaaa gttcgtcaag gaaaaggggt
    47641 tcatgtaaat gttcttctat atagtcttgc actttgcaaa tacgatttag atattctttt
    47701 ttacttttag cgtttgtcat aaatagccct ccttattgtg taaaatgtgt attaatttat
    47761 agtaatatag taataaaatt ttatgttttt gtaatttatg ataaataaga tagcgttcaa
    47821 ttttttataa ttaataaaag ctatttataa ttaataaaaa atgtaagatg cattatatct
    47881 gtctttgcat ataagtataa tcttcgtaat aattagtata ccatagtgat ttatttttaa
    47941 ttgtgcattt atataaatac acaacttatg atatggaaga gttattatgc aaataagctg
    48001 taattaaata aattacaata taaactagtt aaaacataag ccagaaaaat actatcaaat
    48061 ttgttactta gcacaagagc atagaggaga taaaataaga ttgaaaaatt acatactaaa
    48121 tttaataaaa tttttatatt aaaaataata ttaagtttat tgtttaaata aaaaagttaa
    48181 atctacacta ttaacttatt atacttaaaa ctttaaaatg aaaatatcaa agaatacttt
    48241 ttaataaaaa taataattta ataagttatt tggaaatcta aaaactttac aacaaattat
    48301 ctatttaaat tggaggagtg ggaatatgag taatagtttt tatcaattaa attcagcagt
    48361 attatatttt aatgaaaaaa gagatgtaaa tagaataagg tttaatcact atgtaatgag
    48421 aaaagaaaat atacaaagat taaaaggaac tctgccaaga ggacaattta tgatgacagt
    48481 aaggaaagct gcatctgacc ttgatgtatc tacatctaca ataagtagac ttgtaaatga
    48541 atttatagat ttaggtatat tgagattaat aagtagagga gtaaagggaa attgttgttc
    48601 tgtatatagt tatgtttgtt ctgaaaatag taatacggag attttaacag ggaatagtgg
    48661 tattttcaaa aacatagaga aataccttga tgtaaccatt aacaataatc aaaaaacaat
    48721 gaaatataaa catagagatg agttgttcaa gaatagtaat accaacacat acagccgtat
    48781 aaatgaagaa catatagata aaggttatga ttcgataatt catactgggt atgaaacaga
    48841 aaacgagaca aagaaaaaag aattattaaa aaataattta aataaaaaga atttaaataa
    48901 aaataccttt gaaaattcgg atgaagattt gaattatgaa agtccagaaa gtatacatga
    48961 aattattata agaaaattaa atagtgaatc gggaaaaaat tttaaagctg atttaagtat
    49021 aactaaggca cttatagata aaagattaaa agaagggtat agtttagaag atttttacaa
    49081 ggttatagag gcaaaggtaa gaagatggag atatacagat atggaaatat atatagaacc
    49141 aacaattctg tttgggtatg aatttgagtc gtatttaagt gaggagagtt ctttatctgc
    49201 ttgtaattat ggtgatatgt gttatgagga tatgtattga gatatttatt aagatattag
    49261 ttgcttttta gttgtttaaa atatgcttat atataagtat aactagtgta ttaaaaatgg
    49321 aattgtctca aaatagggag aagcctcttt ttaattgttt aaatgatgaa aatatatttg
    49381 atttaataca aaggagagtg cctcatgagc tagaaagctc attttgagac acccactttt
    49441 tttaatatac tggagaaata taacccattt gaatggcttt tgtaatagcc tcaactgatg
    49501 atgaaacatc tagcttgtca tatatgtgtt gtaaatgatt tgataatgtt ctttcactta
    49561 tatacaattc atcagcaatt atttttcttt ttttaccact acagataagc tgtaaaattc
    49621 ttttctccat actagttaaa tcttcaataa ttacttcagt attttcagat ggaaaacaag
    49681 ttcccccttg atagactttt aataatgaat caattaaact atcagggcta atattcttat
    49741 ttaggaatcc atagatacct atttttttag cctcatgttt ataaactggg aggtcgtatc
    49801 cagtcaagat tattatttta atagttgaat tagtttctaa taaattataa gctactttta
    49861 agccatcaca ttcacttaag cctctaaggt ttatatccat taagacaatg tctatttttt
    49921 tatcttgaat catttctgat agactatgga tgtcctgtgt ggaataaaac tgttcgattt
    49981 cttcgtattc ttctagtgca atggacaagc ttttagaaaa aagcatatgg tcatcaacta
    50041 acaaaatatt tataagaaac atctcctttc atagggattg taatctgtac acaaactcca
    50101 tgaggtatat tatcagaaat acttatcgtt cctcctagat tttctacttg ttctttaatt
    50161 gagataatcc ctttgtgttt tattgtatca aaagtaattt tagttatatc taaaggcgtt
    50221 ttaaaagatg tatttttcac accattatca ttaatattta atttaattat atttttttct
    50281 agtgctaaag ctatccatgc atggctacca tttgaatgtt tatatacgtt tgtcaataat
    50341 tctttaatta gtcgatatat caatatatca tatggttcaa ctaagaataa agtatcagaa
    50401 cacttaaatg aaacacaaat gtttttttgt ggaaaggatg aagaaacact ttcaattaaa
    50461 ttctgataat tttcttttac tgttaaattt tttaaaataa cagggtgata gtcttgcatt
    50521 tgttttctta tacatgtatt tagattgtta agtgtttcat atataatatc ttgaacttct
    50581 gggcgatatg acttactcat catgtttttt attgaaagca ggttttgtaa tatatcatca
    50641 tgtaaaaaat tagaaaactc tgtttttagt tgttcttctt gttgtaattt ttccaatgca
    50701 aaagtatact tgctattttt aactacttta tttttttcat ctctaagatt aaactccaaa
    50761 ataatgttac agaggaaaat aagcataaat aaaacattta tagctattaa tattatagaa
    50821 aaattcccac tggcaaatag tacaaccaag ctaattacta atatacttat aaaaagaaat
    50881 atagaccttt gctttatgtt aaaaactgtt gaaataggaa aactatcatt ttctttaagt
    50941 gcaataccat gaatactcat aaaaaatact aatacagtta gatagattcc aaaattacca
    51001 atatgatttg atattcttag tgtaaaaaaa taataagtaa ggaatcctat aattgttata
    51061 aataccgaaa tcgatatagg ttttttttca ctttttatga caaaagcgac ccttttccaa
    51121 tgataaaaaa taatatagaa aaagcttatt atactaacaa caaactgtat tccgtacata
    51181 caagcatacg ttctgttaga aataaatgct cctacaattg caccaatgca ggtgataagc
    51241 aataaaatgt ctgttatctt acggaacttg tatccactac cttgaaacaa aaataaaaaa
    51301 ataaatttaa tagagacata cgctataact gtgcttaata ttttaaaaat aatagtgcct
    51361 attggtgtgg ctacaaatga taagagtaaa taccaactgt ctagtactag taatccacaa
    51421 aacaatgaaa taatgttatt ttctcggaca ttacaagagg ttatatatgt gatgtctatg
    51481 agtaataatg ttgaaattat taagggaata atgctttgga tattcatata agttttagtg
    51541 cttgtagata ttcccatgaa gagaagtgat agaatgtagt ttcctaaaaa tagtattttt
    51601 aaattaaaat ttgtcaatct tatacacctc cttatgagtt aattatatta attttatgac
    51661 taaatcaaac ttaagaatta ataactttga attatattaa ttttatgact gtatcaaatt
    51721 taagaattag taactttgaa ttatatcaat tttataaata tatcaaacct aagaatctat
    51781 agttttaaat tatatcaatt ttatgattga atcaaactta ggaatctata gttttaaatt
    51841 atatcaattt tataaatata tcaaacttaa gaatttataa ttttaaatta tatcaaatac
    51901 ttataaatga agtataccaa atcgtcacac ctttaagctt gacgatttgg taaatattat
    51961 ttttttagta caattttaca acaggattta atagtaaata tataatatat caaatacact
    52021 acagaagtta agaaaattgc aataatcaca ggtatgtatt gtgaaagtga atttccaagt
    52081 aaattctgca tcaaagcagt tttataaacc aaggtagcaa atatacaatc cactatacca
    52141 agtaaaaacg gaatattaaa aaatggcaat acttgttttt taataatttt tttaatttgt
    52201 atattagtat aacccatttt ctgtaaaatt ttataatcag atgttgaatc tgaaattgct
    52261 gatatattgt taaagtataa aatacttcca gaagcaataa agaataatac tacaagaaat
    52321 ccgattaata gaaatgtaga actattaatt gataataaat catttatcct gtgagaatat
    52381 ccttgtaaat aagggcttcc atctaaataa tctgaaatat tactatataa attttcatta
    52441 tttttaattg atttaccatt aatacttaaa atgcttgtca ttgggaattt actttgtgct
    52501 atttgctcat atatactatc attaacgata agtgttccaa cgctattagc aaaagaaata
    52561 gcattgttta atgatgtttc ccttacagtt acaggtgttt ctttaccatt aataagtaat
    52621 agataaatcg ttccattttc actatatcca tcattgtttg gttgatattt cattaaaata
    52681 cattcattat cccttaaagg ggtaagttgt tttattagct ttgttcgatt ttgtgccttt
    52741 aacaaagtat aataatcaga aaaagatata cattcaaatc ctgattctct tgaaataact
    52801 tctttagaag aactactatt agataaatta ttcttagatg caccaatttc atattcaaat
    52861 ggaaggtctt ttgatgaaga ttttacctta taaatatttg tctgtgtaaa aataatatcg
    52921 tctgtattag acatgtattg actgacaatt tgttttacat cttctatttg tttatttttt
    52981 tctactctaa attctatctc tgaaggtgca atacgtgaaa cggatgcaat agggtagtat
    53041 aaagacagtg ccatgacact tgaaactgtc aaagtagcag cagagagtaa tgtaagcata
    53101 attagagttt tagagtttga acggatacga tagataaagt ttggaatagt tattatcttt
    53161 gtacctgtat agaaagctcg tttatttttt ttactctttt gcataatata tggaagaaag
    53221 gaattgataa agagaactgt accaattaca atgataatca tagttatcaa gcctatttga
    53281 taaaatccaa tacttatcca tactgactta gctccacgaa gaatatctag tgataaacaa
    53341 tacccactta aaatcataat aaaccccata aaggctggaa tttttctgaa cttcaatttt
    53401 ttttctgtgc ttttttcata tcgtatcaat tttataagtg aagtcttata aagaaattta
    53461 ccatttgata tagctaagac taaaacaact aatgctataa agataattgt tttgtttatt
    53521 gcatttatat taaaaaatgg tatctgtgaa ttatcaattg ataaattaag tagtgctgta
    53581 attccaaaga caatactctt atgtaccaat gctcctaata ccaatccaat aataaaagct
    53641 ccactacaag ttaatatatt ttcaaaggta agtagcgata agattgtaaa cttacgatat
    53701 ccaagtaaag catatatgcc taattccttt gtacgacgcc ttaagaagaa tcgatttgag
    53761 tatgccatat agaagatgac aaatgccatc aaaaatatcg aaataacatt acacatagat
    53821 tcaactctac catcagttga aattttttct agcattacct tattaacaga aaatgaagta
    53881 aatgcgaaaa atacagtaat aacaaaagag actgaaagta gatatagaga atagaatgaa
    53941 aagttttttt taagattctt tattgccata taaaaaatgt tcattaaatt atcctcctat
    54001 cttttagtat ccaattttgc aatttcttga ataatcaact cataaaatgt atgtctatta
    54061 ttctgttgtt tatttaattc tttaatgata tgaccatctt taaaaattaa aattctattt
    54121 gcaaaacttg ctgcataggc atcatgtgtt accattaaaa ttgtcgtttt caactcttta
    54181 tttgcttctt gtagtgagtg gagtagttca gtagctgaat tagaatccaa agctcctgtt
    54241 ggttcatctg caaagagaat actaggctgt tttactattg ctctaactgc tgaagttctc
    54301 tgtctttgcc caccagataa ttcatttggg tatttgttta attgagaagc tatgccaaat
    54361 cgttcagcta gactctttac cattttttct attttatctg gacttagttt ttgaagtgta
    54421 agaggtactg aaatattttc gaaagttgta agactatcta gtaaaaaata ctcttgaaag
    54481 ataaagccta aattatcctt acgaaaatca gcagcattag tgtcattaag cgatttcaaa
    54541 tttatattat ttatgaaaat gtctccactt gttggtttat caattgtaga taatacatta
    54601 agaagagttg ttttcccaga accagaagct cccattatac ctataaactc accttctgat
    54661 acattaaagg ataccttatc taaactcggc tgttgtcctt tataagtttt agttatgcta
    54721 tttactttta atattgtatt cattgtatat gcccctttca tcttgatata gtcaaattat
    54781 atattaacct tattattcaa tcatgagtaa atcacgcaat aattctacac aaattactta
    54841 tatcataata tattgtttaa aatctaactt tattaggttt gggatgatgg acaagatttt
    54901 aatttaaaag agtgcataga tatataatgg cataatgtgg atttaaatta aaaaaataaa
    54961 gccataaata ttgaaaaatt caatatttat ggctttattg ctttgtaata attaatagaa
    55021 tatatatttt ttattaatca tctatttcaa attctaatat tttaccagta attgcattaa
    55081 ttgttatctc atattcagtt tttcctttta ttatttcacc tttatattct ttgtcatctt
    55141 catcatattt aaattttact attttcccac caggcacttt atctagtatt attgatttag
    55201 ctttttcagc actaataata gaactgttgt cattagtatt agagttatta ttgtgattat
    55261 tatcattatc atcaatgtca tcatcagaat cattgtccat atcaatatct ataattcttc
    55321 catcaaatgc acttatctct aattcatatg ttttcttatt ttttattact ttagcttcat
    55381 attcattatc ttccgcatca tatttacaat agattaaatt accattagga acagcatcta
    55441 gtgctatagc cttagcttta tccaatgata tattttttgt acctaaatta ttatcattta
    55501 agtcatcatc tttttcaatt tctattattt taccagagta ggcatcaatt tctatctcat
    55561 atagaacatt atcctttaca actttgcagt catattcatt atcatcttca tcatagtaac
    55621 aaactaaaat atcacttcct ggaagagttt gttttaatat ttctttagct tgtattaaag
    55681 atattttttt agttttattt cttatgttca cattctttag ttttaaaata tcttcaaacg
    55741 ctttttgatt atatcctcct cctacttgtg ttatttcatc tatatcttta ttttcaataa
    55801 attccttttg actatttaca aggctaccat tagatatcat tataggagaa ttttctttag
    55861 cagctagtac tcctattgat aatgaatcta ctagtgcatt ttcttggcta ataccatctt
    55921 tagctacaaa gacattattt atttttttat ctttataaaa tttatctata atttttgcat
    55981 tagtattgtt tctatctgaa ccactaattc tttctctgtt tggatatttc tttactgcat
    56041 tatcagataa aatcttattt cctccaacta tgtaagattt ttttatagac ctactgttta
    56101 agaaatttac gctactatca ttgctgtttt catctgatac taatattata ggcatattat
    56161 gtattgctgc tggagaagct atactaactg catcagataa tccctttaga ccatttacaa
    56221 ctgcaacatt ttctaccttt tttatcttat ctatttcttt aagtacattt gtagacattt
    56281 catagatatt gtttcctact attttattta tttttatgtt aagcgccttt atttcatttt
    56341 ctactttaga agaaatacta tttccactat ctacaatgta cacattgtct acaccaagcc
    56401 ttttaagttc agctttagtt gaactttcta tgctattgtt gtttactaaa agtataggtg
    56461 cattctttag cttagcaaat ggatttgcac aaagagcact ttgaatagag ttaccattaa
    56521 ctataatggc tgtttttgat tgaacccatc ctaacttact tacttctaca gctgtctcat
    56581 atcttgtttt acctattaat ctttcttgct ttgtagtatt gtctgcaaaa atcgatgaag
    56641 agctagaaaa aaacataata cccgatatta atatagctaa atttttctta ttcatatttt
    56701 tacctcacaa tctttaaaaa ttttttattt agcatactta ataaaatata attttaaaat
    56761 caaattgata ctgaatttga ttttagaaaa taaacaaata aaatttcttt gatacaaaat
    56821 tttcctttta tatttaacat tgtatcacaa atataaagag gaaaaaactt tttaaaaaga
    56881 gtatacacta ttcattttta tcatcttata aataaatctt taccactgtt ttatatgttt
    56941 taaaatagac acaaaactta tttctaaatt tactacaaat attttaggtg aaatttcttt
    57001 ttaagcatat ctaaaaaata tttgtagtaa tgctaaggga ttggatttct taaagtatat
    57061 atttctttgg atgtttgagt ttgtgaaatt tgagaattgg agggtgaaag gaacactcaa
    57121 tggattaata ttaaaaacta catttgtaca ataattgcct taaaactaaa aaaatctatt
    57181 gacttgaagt taactccaag tagtaaagta taattataca ggaattatat acttgtaaga
    57241 atacttaaag tagagagata aaacaaataa gttttaaagg gggaagtaaa acaatggaga
    57301 caaaaaaatt aggatttgga ttaatgcgtt taccaataaa agatgaaaat gatgttacaa
    57361 ctattgatat ggaacatttg aataaaatgg tagacacttt tttagaaagg ggatttacat
    57421 attttgatac agcttatgtg tatcacatgg gaaaaagtga gatagcactt agagaatctc
    57481 tagtaaagag acacaaaaga gagagtttta ctgtagctac aaaacttcca ttaatggctt
    57541 taaagaaaaa agaagagcaa gaaaccattt ttaatgagca attagaaaaa tgtggtgtag
    57601 actattttga ttactatctt ttacacaata taggtgtgtc acattatgaa gtagccaaaa
    57661 aatttgatta aaaaatagct acgcacactc gtgactttag tcatgagtta gtagctaaat
    57721 tagtcagcat atagggaaac ctatatgtag agataggata gaacctatcc aatactactt
    57781 gaattgcta
//
LOCUS       DBGJFK010000016        57750 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.016, whole genome shotgun sequence.
ACCESSION   DBGJFK010000016 DBGJFK010000000
VERSION     DBGJFK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.016"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            645..1847
                     /locus_tag="ACOIAP_001221"
     CDS             645..1847
                     /locus_tag="ACOIAP_001221"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2638124.1"
                     /translation="MKASILITLIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGAVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            1852..2622
                     /locus_tag="ACOIAP_001222"
     CDS             1852..2622
                     /locus_tag="ACOIAP_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGZ2638125.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSSIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYENYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSERSDIELSSGNSNLYKYKKETVNQDIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNNDYEVTVSRSKVKEFRLLMHI"
     gene            2768..4189
                     /locus_tag="ACOIAP_001223"
     CDS             2768..4189
                     /locus_tag="ACOIAP_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HGZ2638126.1"
                     /translation="MVSFLGSIVVLIVGYFIYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGIYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            4455..4937
                     /locus_tag="ACOIAP_001224"
     CDS             4455..4937
                     /locus_tag="ACOIAP_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HGZ2638127.1"
                     /translation="MDTKKYKDKLLKERESLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGTCDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            4986..5765
                     /locus_tag="ACOIAP_001225"
     CDS             4986..5765
                     /locus_tag="ACOIAP_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2638128.1"
                     /translation="MKKSIWGICICLLSIVGVYTYNHNTHNQDDLKEAYSLSENKISD
                     YEDVIIKKGSDDEKVIALTFDDGPDEVFTPQVLDILKKNNVKATFFVVGEKVEYNKEL
                     LKRQYTEGHEIGNHTFTHINVAKNSYDKVEKEITDTQNAVKNVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKKMNIILWSNLDPRDWSNPGVGNIINTILTKVQNGNIILLHDYNNRRN
                     DKSQTIQALEVVIPKLKEKGYKFVTISELIQHLDKNKQVQK"
     gene            5924..6370
                     /gene="lspA"
                     /locus_tag="ACOIAP_001226"
     CDS             5924..6370
                     /gene="lspA"
                     /locus_tag="ACOIAP_001226"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGZ2638129.1"
                     /translation="MLYILIIILLIGLDQLSKMWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHISGKLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            6339..7286
                     /locus_tag="ACOIAP_001227"
     CDS             6339..7286
                     /locus_tag="ACOIAP_001227"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGZ2638130.1"
                     /translation="MFYFLKVKVGDLMYEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKIEKAKYLVKEEDNIVIEIPEPKVLEVVPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKENKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRAKLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            7645..8178
                     /gene="pyrR"
                     /locus_tag="ACOIAP_001228"
     CDS             7645..8178
                     /gene="pyrR"
                     /locus_tag="ACOIAP_001228"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGZ2638131.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDVTLYRDDLEKIDVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            8461..9669
                     /locus_tag="ACOIAP_001229"
     CDS             8461..9669
                     /locus_tag="ACOIAP_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGZ2638132.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFNMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILGLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAFILLIGLGTTYLSNKGISIGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEE"
     gene            9957..11609
                     /gene="cplR"
                     /locus_tag="ACOIAP_001230"
     CDS             9957..11609
                     /gene="cplR"
                     /locus_tag="ACOIAP_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Contributes to intrinsic pleuromutilin, lincosamide
                     and streptogramin A resistance; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein CplR"
                     /protein_id="HGZ2638133.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYIYLTESYSYISQSENNIEICSDSKEKSLLNAPDRFEEYLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEEMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRAYFEYQEYVKEKKRLEKALLHKKSLS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKASIEMKIK
                     IQNGMEIISKNLVEIKDMTLKLGNKLLLDNVSFKIKRGKKIALLGDNGCGKSTMIKEI
                     LNNKNDNIKINNKVKVGYFDQHQSLLDEAKSVLYNTKVNSSFDESFIRTNLNLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLIFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDTKIREFDCNYDEYIINRNKKNPSRESKIKKENLLV
                     LENRLITIVSMLSIEKDGLKKELYESEYNELLKQINKLKNSF"
     gene            complement(11802..13577)
                     /locus_tag="ACOIAP_001231"
     CDS             complement(11802..13577)
                     /locus_tag="ACOIAP_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT RNA binding domain-containing protein"
                     /protein_id="HGZ2638134.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTIKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDAISKDLFIKNLEESEESIFKSIYSKFLGISPIIAKEICYRAG
                     INQNTIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIVIDKKVDRVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNNVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFMSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            13873..14907
                     /gene="ltaE"
                     /locus_tag="ACOIAP_001232"
     CDS             13873..14907
                     /gene="ltaE"
                     /locus_tag="ACOIAP_001232"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HGZ2638135.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDENGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVGLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKDFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            15194..16024
                     /gene="dapF"
                     /locus_tag="ACOIAP_001233"
     CDS             15194..16024
                     /gene="dapF"
                     /locus_tag="ACOIAP_001233"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HGZ2638136.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDSEFKVTSMLM
                     GVPHTVVIVDELDVEDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            16028..16909
                     /locus_tag="ACOIAP_001234"
     CDS             16028..16909
                     /locus_tag="ACOIAP_001234"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HGZ2638137.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            16939..17556
                     /gene="gmk"
                     /locus_tag="ACOIAP_001235"
     CDS             16939..17556
                     /gene="gmk"
                     /locus_tag="ACOIAP_001235"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGZ2638138.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKSAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            17559..17825
                     /gene="rpoZ"
                     /locus_tag="ACOIAP_001236"
     CDS             17559..17825
                     /gene="rpoZ"
                     /locus_tag="ACOIAP_001236"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGZ2638139.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKAKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            17830..19029
                     /gene="coaBC"
                     /locus_tag="ACOIAP_001237"
     CDS             17830..19029
                     /gene="coaBC"
                     /locus_tag="ACOIAP_001237"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HGZ2638140.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVNPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GAGKLANPDIIVEEVLANLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAISRGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILVGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            19304..21793
                     /gene="priA"
                     /locus_tag="ACOIAP_001238"
     CDS             19304..21793
                     /gene="priA"
                     /locus_tag="ACOIAP_001238"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGZ2638141.1"
                     /translation="MKKYAKVIVRSNTIYTDNLFTYQIPVFLSEVIRIGHRILVPFGK
                     GNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWMKNRYLCTYIECI
                     NLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVEKVIESKGKIKVD
                     KLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESDKIDDYIEQNKIN
                     VGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLEFKDYYREPKSIY
                     KSVLKSIKLNNEQQKAVDEIKSNMFLDDKKPYLIHGVTGSGKTEVYMEIIEFALNQGL
                     DSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAVKAGKVRVLIGAR
                     SALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNITLILGSATPSIE
                     EYYRAKYGEYKLINIKSRANDKPLPNIEVVDMKEELDKGNRSIFSLKLQKEIRCAIEE
                     NNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRCHYCGYEKEIPKE
                     CPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGALDDILNKFKDKKA
                     DVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLITQVSGRAGRADKE
                     GKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNMLSVVVSGEDERLV
                     VKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQILFKDENIEINLLK
                     GIIKYICITKRDLIFDKNISVSIDINPNSVL"
     gene            21811..22251
                     /gene="def"
                     /locus_tag="ACOIAP_001239"
     CDS             21811..22251
                     /gene="def"
                     /locus_tag="ACOIAP_001239"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGZ2638142.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHELDHLDGILFVDKIEK"
     gene            22266..23195
                     /gene="fmt"
                     /locus_tag="ACOIAP_001240"
     CDS             22266..23195
                     /gene="fmt"
                     /locus_tag="ACOIAP_001240"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGZ2638143.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDTIKSLNPDVIVVVAFGQILPKGILEIPKFG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDAGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            23205..23957
                     /locus_tag="ACOIAP_001241"
     CDS             23205..23957
                     /locus_tag="ACOIAP_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HGZ2638144.1"
                     /translation="MTDIKKYLTSVGILILILGLLIGVVNFFIISLTQIFSLIINIII
                     ISLILIILCSTAVTYRVIKGKNINSNIMKINFNIVSGLFPIISFIASSFGMSKSEIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCEECGRCNVGELI
                     KLKEKTNVKIFVATGGTLARKIIIDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMIDIEKAIEFLTGKNILACN"
     gene            24026..24727
                     /locus_tag="ACOIAP_001242"
     CDS             24026..24727
                     /locus_tag="ACOIAP_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HGZ2638145.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            24789..26114
                     /gene="rsmB"
                     /locus_tag="ACOIAP_001243"
     CDS             24789..26114
                     /gene="rsmB"
                     /locus_tag="ACOIAP_001243"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGZ2638146.1"
                     /translation="MDAREVGFKVLCDIEKNNNYSNIAINKHFKNLEISDIDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANSEKPSIYIRTNMLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEDSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLIKSTVNRLGLKNVCVERFDASEIDENSISKFDYVLADVPCSGLG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASRYVKVGGTLVYSTCTIQDDENINIVAS
                     FVEENHNFEFDSIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            26122..27153
                     /gene="rlmN"
                     /locus_tag="ACOIAP_001244"
     CDS             26122..27153
                     /gene="rlmN"
                     /locus_tag="ACOIAP_001244"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGZ2638147.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     EDMNNIPKSLRNKLEEISCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIKEILDACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            27173..27925
                     /locus_tag="ACOIAP_001245"
     CDS             27173..27925
                     /locus_tag="ACOIAP_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGZ2638148.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            27942..29945
                     /gene="prkC"
                     /locus_tag="ACOIAP_001246"
     CDS             27942..29945
                     /gene="prkC"
                     /locus_tag="ACOIAP_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861606.1"
                     /note="PrkC, as found in Clostridium difficile, has a
                     kinase domain, two PASTA domains, and a C-terminal
                     Gly-rich repeat region; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing Ser/Thr kinase PrkC"
                     /protein_id="HGZ2638149.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPILAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     EEEEEIMRAKKNQRTKSAPSKRTKKKKKKQESPKSRRRLKVIATVLILILCAQVFLAY
                     KFLFSGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCIISQTP
                     EGGSTNIKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYEYSSI
                     YKEGTVLNQSPGAGSSRVQEGDEISLYVSKGSEKSNTQTPTVPNKTPTTPNNDTPTEP
                     GSNSGSSGGSSGGSNSGNSGGNSGNNGNNSGGSNSGNSGGNSGGSNSGDNGGNSGGSN
                     SGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            30053..30790
                     /locus_tag="ACOIAP_001247"
     CDS             30053..30790
                     /locus_tag="ACOIAP_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGZ2638150.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTRLNEENFSIKLFKADVSNREDVENMVDYCIKEFGGLDVLVNNAGISQDKLFTDITD
                     VDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDILVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            30888..31772
                     /gene="rsgA"
                     /locus_tag="ACOIAP_001248"
     CDS             30888..31772
                     /gene="rsgA"
                     /locus_tag="ACOIAP_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGZ2638151.1"
                     /translation="MLEGKIIKGISGFYYVDTHNGIYECKARGIFRKHKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKKIYELSGYKVIPVSNITKLNIEKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVANGEISKERY
                     ESYIQLLNEIRQNNSRRY"
     gene            31777..32448
                     /gene="rpe"
                     /locus_tag="ACOIAP_001249"
     CDS             31777..32448
                     /gene="rpe"
                     /locus_tag="ACOIAP_001249"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGZ2638152.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPIDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVDKVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            32457..33098
                     /locus_tag="ACOIAP_001250"
     CDS             32457..33098
                     /locus_tag="ACOIAP_001250"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGZ2638153.1"
                     /translation="MKICIVLNGEIEDYEVTRGIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     KGDAKGVTLTGLEYPLDNYYMRYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            33229..33858
                     /locus_tag="ACOIAP_001251"
     CDS             33229..33858
                     /locus_tag="ACOIAP_001251"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2638154.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIDLSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERNNLLNECSLKECEYLSENGAKLFDDIENTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFVDFECPGNTGLHKGENNKLIIERNKLKNPI
                     YIGDTQGDANSAKFAGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            33913..34569
                     /locus_tag="ACOIAP_001252"
     CDS             33913..34569
                     /locus_tag="ACOIAP_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2638155.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVIIKRRDLMEKIADVITKKQQEILVEMEKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            34964..35686
                     /locus_tag="ACOIAP_001253"
     CDS             34964..35686
                     /locus_tag="ACOIAP_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2638156.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIIDIMMPKMDGITLTMKLRENHNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVENKEQKVDDDDGVFAIGGLELNENTKEVSVDG
                     KHIKATPIEFKILSLLMRNAGRVFSADEIYERVWNDNAVNTDTVMVHVRNIREKIEVD
                     PKNPKYLKVVWGVGYKIEKIQR"
     gene            35652..37988
                     /locus_tag="ACOIAP_001254"
     CDS             35652..37988
                     /locus_tag="ACOIAP_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2638157.1"
                     /translation="MLDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGG
                     AKNPFEQESFVDNMYKGSYVLYHNMKEEQEGKMIQPSKLFISKETMNYIKNVSKEKDT
                     YDGSETYYTDDSINADFNQNFENWESFIKESGKNLKYYLVDKESNFEFFNDNKELGAL
                     DTTKNYASKEDSDENKSKNTEMSDEERQKQIKDIKENYRFYIVMNFDKDGKVNVLDSY
                     GVNQKVISQMLLSKAREDLMNTTLGGNPISYKLSPIKNVTLVYAVPKVISKGDGGEYS
                     YGNIYNNDSISSYINNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTL
                     SRIPLEILFIILAILQGIVDLYPTSIISNTLSGNYVEYLINNDISAKMASILVSLMNL
                     TYWFVIFSIIFVFIILLKHILNVGIKEYFIKNTVTGMFFVWLIKSGKVVINQIRITDL
                     KEKPNKTIAIILGINLLIIVIMCSFWFFGIILALIYSVVLFKILSDYSKKTIYEYNQL
                     LDVTKKISDGNLEVNMERDLGFFNPIKDELGNIQAGFKKAVDEEVKSQKMKTELISNV
                     SHDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKVNSG
                     DVHLNIMNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENL
                     IINISKYAMPNSRVYIDILETDNKVSIMLKNMSATEIDFSVDDIMERFVRGDKSRNTE
                     GSGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(38267..40945)
                     /gene="mngB"
                     /locus_tag="ACOIAP_001255"
     CDS             complement(38267..40945)
                     /gene="mngB"
                     /locus_tag="ACOIAP_001255"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HGZ2638158.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRKKLAIGPWYTQTDQLVISGESIVR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDTIGKLKVKSSTNNVYFPNG
                     FDQAPIRKNLPDILKKANKIDTENEYEISDIENYVDSVRNERNEFTELKGEFVNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLILKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDFHMRLISTQIKNNNEEITLTVFNGL
                     PEARNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITDYILTQTIKLNPSKKIYI
                     PKTVYRAKIALSVKNIPPMGYTQLIVELDTKNKCEIKTSSCKKIENKYYKITANKNGS
                     VEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNVQEE
                     MTLKYSLTIPASLEERTIGKVSVKMPVTMKITLEPKEQIIKFNINIKNDQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTALEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQKGVALITGCVREYQIVGANLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFNFGLYIYNNKFDKSNIANTAKRFLTPIQIYEYADFLNGRLIFVFNDEKQ
                     IYENEYSFMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDSKGSLNINKNINAAYN
                     AMLDEIYDNTNKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(41019..42125)
                     /locus_tag="ACOIAP_001256"
     CDS             complement(41019..42125)
                     /locus_tag="ACOIAP_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGZ2638159.1"
                     /translation="MSKKNNSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPSMGAGFIGGL
                     IASNTNAGFLGAVTAGFFAGYICKFLKKKIKISGSAAGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGSMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSRFSKTLSETGKGNIVMGIIGITEGAI
                     PFTLKNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISVGSGWAYLVGAIF
                     GALVIAILSTILVDFNEDETAENTEFDEIELDIM"
     gene            complement(42240..42548)
                     /locus_tag="ACOIAP_001257"
     CDS             complement(42240..42548)
                     /locus_tag="ACOIAP_001257"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGZ2638160.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHKIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGVALKKPEAVLTKCIETIS
                     "
     gene            complement(42551..43003)
                     /locus_tag="ACOIAP_001258"
     CDS             complement(42551..43003)
                     /locus_tag="ACOIAP_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2638161.1"
                     /translation="MVLQEKNIFIDKDLKSKEEVLNFIADSAYILGITTNKDALLKDL
                     LKRESEFPTGIRDGFAIPHTKSANVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HENEGNIHLKTLSKLATCLMEDDFISEVKNASDASHLVKYITNKMKEE"
     gene            43238..45166
                     /locus_tag="ACOIAP_001259"
     CDS             43238..45166
                     /locus_tag="ACOIAP_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2638162.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSINE
                     TLEKNGAIIKIKKGEGYYIDILNLALYQHYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQKIVLSEINKFNINFLDFNLK
                     NFIIHLSITISRILGGYCLDNVLDVVLTDFQSNTAVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRADTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEISLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSRIYSNLLDNFFDKNLF
                     IVNPKIKEKDELIKLMCNKLTQSEIVIPSFTESVFYRESLSSTNIDDFLAIPHPMELS
                     SIKTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDSFLSIIKSII"
     gene            complement(45425..46186)
                     /locus_tag="ACOIAP_001260"
     CDS             complement(45425..46186)
                     /locus_tag="ACOIAP_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2638163.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKKHHNKLLVKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIRENYGKDIIVASNKKFKNMSK
                     QDYEDWQNLSIEIISKLKKAFKTGDASSELAQEVARLHHKWLSYTWSTYSKEAHASLA
                     QMYVCDERFTSYYDKEQPGLTKFLRDAIVVYTRDN"
     gene            46405..46881
                     /locus_tag="ACOIAP_001261"
     CDS             46405..46881
                     /locus_tag="ACOIAP_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HGZ2638164.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDVIYKVFSKNGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            46979..47131
                     /locus_tag="ACOIAP_001262"
     CDS             46979..47131
                     /locus_tag="ACOIAP_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HGZ2638165.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(47291..47479)
                     /gene="rpmB"
                     /locus_tag="ACOIAP_001263"
     CDS             complement(47291..47479)
                     /gene="rpmB"
                     /locus_tag="ACOIAP_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGZ2638166.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            47840..48190
                     /locus_tag="ACOIAP_001264"
     CDS             47840..48190
                     /locus_tag="ACOIAP_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGZ2638167.1"
                     /translation="MSAKVTNQYGSIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            48209..49852
                     /locus_tag="ACOIAP_001265"
     CDS             48209..49852
                     /locus_tag="ACOIAP_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGZ2638168.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKDLVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVETDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGDFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGNNIEIKNADLDTNI
                     STSMDFAKSTISTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKDINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALSSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            49933..51990
                     /gene="recG"
                     /locus_tag="ACOIAP_001266"
     CDS             49933..51990
                     /gene="recG"
                     /locus_tag="ACOIAP_001266"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGZ2638169.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDSEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKDLIIQEYMPQRIIDKYRLCSIDFAVRNIHSPNSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIINALPFKLTKAQNRALGEIIQDMDSEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQVKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGVNPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETLAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMGLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            52049..52603
                     /gene="rsmD"
                     /locus_tag="ACOIAP_001267"
     CDS             52049..52603
                     /gene="rsmD"
                     /locus_tag="ACOIAP_001267"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGZ2638170.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKACTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            52605..53102
                     /gene="coaD"
                     /locus_tag="ACOIAP_001268"
     CDS             52605..53102
                     /gene="coaD"
                     /locus_tag="ACOIAP_001268"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGZ2638171.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            53106..53630
                     /locus_tag="ACOIAP_001269"
     CDS             53106..53630
                     /locus_tag="ACOIAP_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638172.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLKEIL
                     EEVKRDKAELRPKK"
     gene            54059..55351
                     /locus_tag="ACOIAP_001270"
     CDS             54059..55351
                     /locus_tag="ACOIAP_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HGZ2638173.1"
                     /translation="MEGVKVGMLKKLCSLAMVAIMTTTLITGCTSGNGKDSKKDGEKE
                     KLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISAGEGPDV
                     GYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAANPGVLY
                     YNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFGNLNWNW
                     YPYLWQAGGDIFNNDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEMIESVFG
                     PGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSSAKNKEL
                     AYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKDVYRPLVVGPHG
                     VEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            55449..56366
                     /locus_tag="ACOIAP_001271"
     CDS             55449..56366
                     /locus_tag="ACOIAP_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGZ2638174.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVTFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTIVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGAIWSLQVFDLVYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            56382..57191
                     /locus_tag="ACOIAP_001272"
     CDS             56382..57191
                     /locus_tag="ACOIAP_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGZ2638175.1"
                     /translation="MKTTRRILSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFLNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            57248..57421
                     /locus_tag="ACOIAP_001273"
     CDS             57248..57421
                     /locus_tag="ACOIAP_001273"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638176.1"
                     /translation="MEISYVLKDCTFKHNKYSVIETETWEDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTID"
BASE COUNT        22512 a         6248 c        10034 g        18956 t
ORIGIN      
        1 taataaaaat tttctggaat ttttattatt atacgtgata aaaatagtta tgatcatata
       61 attcagaaaa taaaatttag gggtatccct tttggaagaa ttatttaaca ataattatgg
      121 aagtaacttt caaggttggc aaattattat ggtaaatata cattataagc attataatga
      181 tttattgtta aacatattat tttaaatata ggatttattt actttatcca tatacggcta
      241 tataataaat atataacaca gagatgataa tgtgtgttta gcacaattaa atcaaatgag
      301 atatttgaac aaagaatagt ataaaatttt taaagaaata tgttgtatga gtaataatct
      361 acataacatt gtattatata atattcgaaa gtattacttc taagaaaaga gatttctaaa
      421 gtataaaatt aaatactaga attgtaaagt taatgataac tacaagttat tacaagcttg
      481 tgttagtcag ttagtattag ttgttaatag aagtatatcc atttttttat ttaattaaaa
      541 ggttaaatgt ggaaaatgtc gagataggat tacttcaaat atacaattta caacaaacat
      601 aataaattta gagtgtgtaa agatttattt tttaaagggg aaatatgaaa gcatcaattt
      661 taatcacatt aatagaaaag acaagcctca ttgtagtact atttcttcta ataacaaagt
      721 taaaaatatt taagcagata tttcaaaaag aagaatatag ctttaatgat ttggtctgta
      781 tagcattagt ttttactttt ttagccatat ttggaactta cagtggtata aattatatgg
      841 ggtcaatagt aaacactaga ataatatcta tagtatcagg aggcatttta tttggtccaa
      901 tggtaggtat tacagcagga gttttttcgg ggattcatag atattttatg gatattggag
      961 ggataacatc tgttccgtgt cttttatcaa gtatactagc aggtgtatta tcaggatttc
     1021 tatataagag gataccaaag caacatagag taatgtatgg tatattggta ggcatgattt
     1081 ctgaaagttt tactatacta cttatatact taatatcata tccacattct ttagcaattc
     1141 aaataattgg tggaatatat ttacctttaa tagttgggca gattggaata ggatttgtta
     1201 tatctatagt agaggggatt gagaaagata aaaaggatat agaagcgaga aataaagcag
     1261 aaataaaagc acttcaaaga caaattaatc cacatttttt gtttaattcc ctgaacacaa
     1321 tagcttcatt tataagattt agtccagata aggctagaga gttaataata aatttatcaa
     1381 cttatctaag atataatctt gaatatagtg ataatttaat tgatataaat aaagagattg
     1441 aacaggttaa atcttttgta gagatagaaa aggctagatt tggagagttg ctaacagtat
     1501 cttatgatat agaagatgta aatataaaga ttccaagttt aattatacag ccactagtgg
     1561 aaaatgcaat aatacatggt attttagaaa gtggtagagc tggtgcagtg aaaatatcca
     1621 taaaaaagtt gccatattca ttagaaaata ctgtgagaat atcaatagag gataatggta
     1681 taggcataag tgaggaaatt ataaataatg tatatcaaga caatatgcca gaaaataaaa
     1741 ttgggcttta taatgtacat ttaaggctta aactgatgta tggaagaggg cttaatataa
     1801 gaagaataga taatgggact ttgatagtat tttatgtaaa ggagtagaag tatgagagct
     1861 ataatagtgg aagacgagtt tccagcaaga aaggaattga gatattttat tgaaaataaa
     1921 agtagtatcg aggtagtaag tgaatttacc aatggtatag aggtattaga ctttattcag
     1981 gaaaataaaa tagatgtaat ttttttagat ataaatatac ctcatcttga tggaatgcta
     2041 cttgcaaaaa cattaaatca gtttaaatca agacctaaaa ttgtttttat aacagcatat
     2101 gaaaattatg cagtagatgc tttttctttg gacgtatttg attatatatt gaagccatat
     2161 tctgaagagc gaattatttc tatgctgaat aaattagaaa aaagtgagag gagtgatatt
     2221 gaactgtcta gtggtaatag taatttatac aaatataaaa aagaaacagt aaatcaggat
     2281 atagaagaaa taacacataa aattagcctt tggaaaggtg ataaattggt tgtaatagat
     2341 attgatgata tatattattg tgaagctaat gaaaggcaga cattcatata tactgagaaa
     2401 gaaaagttta tattaaaaga aggcatatca gaagtcgaaa atcttataaa tgataaaacg
     2461 ttttttagaa cacataggtc ttatatcgta aacttaacaa aagtaaaaga aattataccc
     2521 tggtttaata atacatacat attgaaatta aaaaataatg actatgaagt aactgtcagt
     2581 agaagtaaag taaaagaatt taggttgtta atgcatatat aaagtcattt catgtactta
     2641 aatatgcact taatgtaatt aatatttata ttagcataaa aaagtattac tatttgaact
     2701 ggaaatagtt ttcttaaact cataaaaatt tataaagcaa ttatataaaa actaagggga
     2761 tgaatttatg gtaagttttt taggttcaat agtggtactt atagtaggtt attttatcta
     2821 tggtactttt gtagaaaagg tttttggaat caatgacaaa aaccaaactc cagctatagc
     2881 ctgtagagat ggagtagatt atgtgccaat gaaatggaag agaatctttt taattcagtt
     2941 tctaaatata gcagggttag gtcctatatt tggagctata caaggggcgt tatttggacc
     3001 atcagcattt ttatggattg tatttggaac aatctttgca ggtggagtac acgattttgc
     3061 ttcaggatat ttatcaatga agaacaaagg tacatctgca tcagagttgg taggtattta
     3121 tctaggaaat ggtgcaaaaa tagcaatgag aatatttagt gttattcttt tagtattggt
     3181 tggagttgta tttgtaacag gtccagcagg attgttaaag acattgacag gtgtaaacgc
     3241 acaaatatgg gttggagtaa taatacttta ttatattatg gctactgttt taccaataga
     3301 taaattgatt ggaaaaatat atcctttatt tggagcagca ttattaatta tggcagtagg
     3361 tgtagctgga ggattaataa taaagggata taacatacca aatataaatt tacaaaatat
     3421 gaatccaaat ggaacacctt tattcccata tttatttata acaatagcat gtggagcaat
     3481 atcaggtttt catgcaacac aatcaccact tatggcgaga tgtgttgaaa aagagagtga
     3541 ggcaagacca gtattttatg ggtcaatggt tgcagaaggt ataatagctt tagtttgggc
     3601 agcagcagcc atgtcatatt tccatggtat acctcaactt aatgtaatat ttaatgatgg
     3661 tggtgcagca acagtagtaa acacagtatc tgttggatta atgggtccta ttggaggagc
     3721 tttagctata cttggagttg tggcatgtcc tataacttct ggggatacag catttagaag
     3781 tgctaggcta acaatagcag atgcaatgaa ttataatcaa gatgcagtaa aaaatagatt
     3841 tttaatagct ttaccattgt tcgcggttgg cgttgctctt acatttatag attttaatat
     3901 aatttggaga tatttctctt gggcaaatca aacacttgca atgataatgt tgtggactgg
     3961 ttctgcatat ttagttaaag caaataaaaa ccattatata actacattac cagcactttt
     4021 tatgactgta gtaacattta gttatataat gcaagcaaaa gaaggattta gacttccagt
     4081 taatatatct aatggaatag gtgttattgt agcaataatt cttggtcttt tattctttaa
     4141 aaaagcgaaa catattaagg aacaaaataa tcataaattg gcaagttagt aaaataataa
     4201 ctataaaaat taaaaattta tatttaaact atgttcaaag aagaggctgt ctcaagatag
     4261 agataagtct ctttttcatt gtgaaattat aaaaaatata tttgacttta tacaaaaaag
     4321 aggatttaat gaactaaaaa atttattttg agacattcca ttttttgaat caaatcttat
     4381 ttttattgta tgtttaattt acttttccac atactatttt tatgatataa atattaaaat
     4441 tagaggtgtt aaaaatggat actaaaaagt ataaagataa attattgaaa gaaagagaaa
     4501 gtttaactaa tttagtagag gatatgaaag ataatacttt atttggagat acgactaaac
     4561 atacaagcga aaagtattca tcaggagaat tatctagtta tgataatcat ataggagaca
     4621 tgggaacaga tttatatatg caaaatatgc aaaacagtct aataaatcat gaagagggaa
     4681 gattatatca aatagattta gcattatcta aaatagagaa tggaacatat gggacttgtg
     4741 acttatgtca taatcaaata gatttagaaa gattggatat attgccagat acaagtttat
     4801 gtaatgattg tgcaaagaaa gaaaataatt tattaggtga tgcaatgcaa aatcctgatg
     4861 tagaagattc taatttttat tcagaagacc taacaaattt aactgattta aataagaatg
     4921 gaatattaag agattagaaa actgaatcat atattgttag aatgaattag aaaagaggta
     4981 atgacatgaa gaaatctata tggggtatat gtatatgttt attatctata gtaggtgtat
     5041 atacatataa tcataataca cataatcaag atgacttaaa agaagcttat agtttgagtg
     5101 aaaataaaat tagtgattat gaagatgtaa taattaaaaa gggaagtgat gatgaaaagg
     5161 tcatagctct aacgtttgat gatggtccag atgaggtatt cacaccacaa gtacttgata
     5221 tactaaaaaa gaataatgtc aaagcaactt tttttgtagt tggagaaaaa gtagaatata
     5281 acaaagaatt attaaaaaga cagtatactg aaggacatga gataggaaat catacattta
     5341 cacatataaa tgttgcaaag aatagctatg ataaggtaga aaaagaaata acagatacac
     5401 aaaatgctgt aaagaatgta atcggagtag aaccaaaaat atttagacct ccatatagag
     5461 caatgagtaa gagtgtttgt gatattatag tttctaaaaa gatgaatata attctctggt
     5521 caaacctaga ccctagagat tggtctaatc ctggagtagg caatattata aatactattc
     5581 ttacaaaagt tcaaaatggt aatataatac ttttacatga ttataataat agaagaaatg
     5641 ataagtcaca aactatacaa gctttagaag tagtaatacc taagctaaaa gaaaaagggt
     5701 ataagtttgt aacaatatca gagcttatac aacatttaga taaaaataaa caagtacaaa
     5761 aataaaaaat aattattaaa atattaatga tgcttgtatt ttaaatttat aagcatcatt
     5821 aatattttaa gatagttgct ctttagagca ttttttttgt ataataataa tagtgtgttt
     5881 caaataaaat tgttttttaa ataatttata gggggaaaaa tcattgctat atatattaat
     5941 aataattcta ctcataggct tagaccaact gtctaaaatg tgggtattga ataatttggt
     6001 agatgtatca acaataccaa taataaataa tgtatttcat ttaacttatg tggaaaatag
     6061 aggtgcagca tttggattat tacaaaataa tcaatggata tttataattg ttgcattact
     6121 tgcaacagta tttgggttat actatcttaa tacaagaaaa gtacatatat ctggaaaatt
     6181 gggaattata ttaattatat ctggtgcatt gggaaatcta attgatagag tacgattagg
     6241 ttttgtagta gattacttcg actttagaat tatatgggaa tatgtattca atgtagctga
     6301 tgtatttgta gttgtaggaa ctgtgttttt atgtatatat gttttatttt ttgaaagtaa
     6361 aagtaggtga tttaatgtat gaagtaaaag agtttttagt acttgaagag gaagaagaag
     6421 ttagacttga tatttatcta gcagaacaat taggtgatat gtcaagaagt tatatacaaa
     6481 aaattataaa agatggaaaa gtaaaggtta ataataaaat agaaaaggct aaatatctag
     6541 ttaaagagga agataatatt gttatagaga taccagaacc taaagtatta gaagttgtac
     6601 ctcaagatat tccaatagac attgtatatg aagatgatga tgttttaata ataaataaac
     6661 ctcaggatat ggttgtacat cctgctcctg gaaactatga aaatacgctg gtaaatggga
     6721 ttttatatca ttgtaaagat aagttgtcat caataaatgg agttattaga cctggtatag
     6781 ttcatagaat agacaaagat acttctggtc ttcttatgat agctaagaat aattatgcac
     6841 ataattttct agcagaacaa ttaaaagaac atactataac tagagagtat gaatttatat
     6901 gctatggtgt ggttaaagaa aataaaataa ctgtggataa acctataggg agaaatccta
     6961 aggatagatt aaaaatggct gtagtaaaag atggaaaaaa tgcaatcact cattttgaag
     7021 ttgtagaaag atttgataaa tttacacata tgagagctaa gcttgaaact ggtagaactc
     7081 atcaaataag agttcatgct ttgtctataa atcacccact tttaggtgat tatgtatatg
     7141 gtccaaaaga aactaaattt aaattaaaag gacaaacttt gcatgctaag aagttgggat
     7201 ttatacatcc tactactaag gaatatatcg aatttaattc agaattacct gagtatttta
     7261 aggaagttat taaaaagata aaataatcat ttgtataata cttataaatc attttttgtt
     7321 tttatgtaag taaataaatt tagtgaaatt taaataaaat atcttatatt aaagtatttt
     7381 gtttaaaaaa gcttgaaaaa tttgaaatat aaatatataa tttgaattga tagattaaaa
     7441 aattatcttt aaacgataca gagatatcgt aagacaattg ctaaattaca ctgtatattt
     7501 tttatataag agcttcttgt cttgtgatga gaagtttttt gttgtttaaa ttgaaatttt
     7561 aagtaaaaat aaatttataa aaatttaaaa gaaaggagta gatttgtcaa atagatatat
     7621 tatatctttg acaataatta tgatatggta gaaaaagctc aattaatgga tgaaaaggca
     7681 atagcaagag caattactag aataagtcat gaaataattg aaagaaataa aggtgtagaa
     7741 aatctagttt tagttggaat aaaaactaga ggtgtaccaa ttgcaaatag aatttctaag
     7801 aaaatagaac agatagaagg aacaaaagta gacacaggag atattgatgt gactttgtat
     7861 agagatgatt tggaaaaaat tgatgtcgaa cctgtagtta aaggaactta tttagatttt
     7921 aatgtaaatg ataagacagt agttttagtt gatgatgttt tatatactgg aagaactgtt
     7981 agagcttcac tagatgctat tatagatata ggaagaccta aatcaataca attagcagtg
     8041 ctagtggaca gagggcatag agagttgcct ataagagcag attatgtagg aaaaaatgta
     8101 cctacttcta gacatgaaat tatatctgtt agtttattag aaattgatgg agaagattca
     8161 gttacaatca aagaataata atttttaagt attatataaa agcttagcat tgaatagtca
     8221 ggaaggagga taaagcttac atagattgca caaaataaat attataattt tatggatgtg
     8281 ggtcttaatg tagtctttat tctcctttat ttgagttttg atgtcgtaaa atgtaaaata
     8341 ataataaatt atataataag tatatagagg ttaaaaaata gaatctaggg aatgataatt
     8401 aattaaaaga tattaattaa acagaggatt tatttatata taataatttt ggaggttttt
     8461 atgaaaaaaa cgataatgtc tttacaacat ctattagcca tgtttggagc gacagtatta
     8521 gttcccattt tgacaggttt taatccgtca gttgcaattt tctgtgctgg tgttggtaca
     8581 ttgatatttc atttttgtac agaaggaaaa gtacctgcct ttttaggttc aagttttgcg
     8641 tttataccag ttatattagc agctaaagag gcgtatggtg gagatttagc gtatgctcaa
     8701 ggtggtataa tagttgcagg attaatttat attataatgt cgattatagt aaaaatagtt
     8761 ggagtaaata aaataaaatt atattttcct gcacaagtta caggagctat gatagtagtt
     8821 ataggattaa atttattgcc aacagctttt aatatggctt cagccaattt tgtaatagca
     8881 ttcataactt tagcaatagc aattttaacc aataagtttg gtagaggatt tataaaacaa
     8941 ttaggaatat taatagccgt tttttctgga tatataatct gtttgatatt aggattagta
     9001 gatataacta caattacaga ggcaagttta tttgcaatac ctaactttac agttcctaag
     9061 tttagtttag gagcaattgt gattatatct ccagttgtgt tagctgtatt tatggaacat
     9121 ataggggata tgactactaa tggtgctgta gtaggtaaaa attttataga aaatcccgga
     9181 ttaaatagaa ctttacttgg ggatggattt gcaactatag ttgcaggttg tttaggaggt
     9241 ccagccaata caacttatgg tgaaaataca gcagtacttg ccataactaa aaattatgac
     9301 ccttcaatac ttagacgtac agcaatattt gccatattgc ttgcatgtgt aggaaagttt
     9361 ggtggatttc ttcaaagtat accaggttca gttatgggtg gaattagtat aatgctattt
     9421 tcaatgataa cttatgtagg attaaaaact ataagagata gttcttgcgt agaaagtaag
     9481 ataaatatat tgataatagc atttatatta ttaataggtc ttggaacaac atatttgtct
     9541 aataaaggta tttctattgg aatccctata acaagtacag taaagataac tggccttagt
     9601 ctagctgcaa ttgttggaat tgtattaaac agaattttaa ataatcagga ttttaaagtt
     9661 gaagaataat aaattgtata ttgaataatt taaattagtt aattttctat agacatttgt
     9721 aattaatgtt gatataatga ttaaaaataa atgaaagaaa gggcaaggta actgggacaa
     9781 tgagaatata atctattttt tataattaaa gtattgtaat ttttgaaaag cctattttgg
     9841 tggctttatt tgcgatgctt aaattaagga gagtagatta tagtctatac gtttatttgt
     9901 tatgcctatt tatagaatct ctccttatat ttaagagtgt taaggaggga ttttttatgt
     9961 tattagtaaa agtagagaac ttaaaaaaat attatgcaga caaattaatt ttagatatag
    10021 ataaacttga aatattagaa aacgacaaaa tagggctagt tggttcaaat ggtcaaggaa
    10081 aaacaacatt attaaaagca atattgggtg aaatagaaat tgatgaagga tatatttacc
    10141 ttacagaaag ttattcctat ataagtcaga gtgaaaataa tattgaaata tgtagtgata
    10201 gtaaagagaa gagtctttta aatgctccag atagatttga agagtactta tcaggagggg
    10261 aaaaagttaa gttaaaaata gcagatgcac tgagcaataa aaaaaatatc ataatagctg
    10321 atgagccgac ttcaaactta gataaaaaaa gtattggagt tttggaagag atgtttaaaa
    10381 ggcatgaggg agcattatta ttaatatctc atgatagacg ttttctggat gagttgtgta
    10441 caactatatt agaactagaa gatggaaaac taaaagccta caaaggcaat tacactgatt
    10501 atttaatgca aaaagatgaa gaagtaaaaa gagcttattt tgagtatcag gaatatgtta
    10561 aagagaaaaa aaggcttgaa aaagctcttt tacataaaaa atctttaagt gatggcataa
    10621 gaaaaacacc aaaaagaatg ggtaattcag aagctagatt gcacaaaatg gggggtcaga
    10681 ctaataagaa aaagttggac tcaaatgtga aggctataaa aagtagaatt gataaacttg
    10741 aggtaaaaaa taaacctaaa gcttctatag aaatgaagat taagattcaa aatggtatgg
    10801 agataattag caaaaatcta gtagagataa aggatatgac tctaaaatta ggaaataaac
    10861 tgctattaga taatgtttct tttaagataa aaagaggtaa aaagatagca ttattaggtg
    10921 ataatgggtg tggaaaaagt actatgataa aagaaatatt gaataataaa aatgacaata
    10981 taaaaataaa taacaaagta aaggtaggtt attttgacca acatcaaagc ttattagatg
    11041 aggcaaagag tgttttatac aatactaaag ttaatagttc atttgatgaa tcttttataa
    11101 ggacaaactt aaacctgttt ggatttaaag gagatgatgt ctacaaaaaa gtaaaagtac
    11161 ttagtggtgg agaaaaggta aaaatagcac tatgtaaaat aatattggaa gataataatt
    11221 ttttaatatt tgatgaacca acaaattact tagatataaa atctatggaa gcactagaaa
    11281 aggcactgat aaatactgat aaaactatgc ttatagtatc tcatgataga gtatttgtat
    11341 cacatatttg caactatatt atagagataa aagacactaa aataagggag tttgattgta
    11401 attatgatga atatataatt aatagaaaca aaaaaaatcc tagtagagaa agtaagatta
    11461 aaaaagaaaa tcttctagta ttagaaaata gacttataac tattgtatct atgttatcta
    11521 tagaaaagga tggtctaaaa aaagaacttt atgaatcaga atacaatgaa ctactaaaac
    11581 aaatcaataa attaaaaaat agcttttagt attaactttt taattatatc tatataagaa
    11641 gactaaaaat acttattagg aatataagta tagttattag aatataaaag tgtgttgatt
    11701 agaaagtggc cttattattg tacttcataa taagaccact attttcattt taaatgataa
    11761 tgtgtgcttg tctaacactt attttatatt tagtgcagaa tttattcaga tttaacctta
    11821 agtttagcta ctgtttcttc ttcaggagta acataaatag tactgttagt ctcataaata
    11881 accatacctg gtttagaacc actaggtttt tttacatttt ttcttttagt ataatctaca
    11941 ggcacctgag aagaaagttt tgacttacta aagaatgcgg ctagcatggc tccttcaaat
    12001 acagtattat cagggacttc tttaccagca cactttatta ttacatgaga accaggaata
    12061 ttctttgtat gcatccataa gtcgtcgtta tcagcaagtc ttagtgtaag atagtcattt
    12121 tgcttgttgt ttttaccaac caatatttta aatccatcag aagacataaa ttcatgaggc
    12181 tttgtagatg gaatagtatc ctttttactg tttttctttt gagtcttgat atatccaact
    12241 ttagcgagtt cctcttttat atcttgtaat tcagctaaat tttcacaatt ttcaatactt
    12301 aaaattatat tttctaagta atctatttct tccttattta aggaaatttg atgagatatc
    12361 tcgactttag catgtttcat tttattatac tttttaaagt atttttgagc attttcagat
    12421 ggtgtcaagt ttttatttaa ttctattgtt acattattac aattttcatc atagaagtta
    12481 gcaacttcaa tactttccat acctttttct accatataga tgtatgaagt aatcaattct
    12541 ccttttatct tataaatatc tgcattttca gattctgata attcttcttc ttgtttttta
    12601 agtttattat aaagtctatc aagtttaaca gatatgctct tttttaaatc agatgaacgt
    12661 tgattaattc tatctttaat atctttagtt ctatagaaat cttcaagtat acgagacata
    12721 ctatccttat ttatatatga taaatcacta aataatgtaa ggtttataca gctgaaatca
    12781 actaccctat ccaccttttt atctataaca atgcaaggtg agtatttatt agaatttata
    12841 tcattaaata aattacaaaa tactttgtgt aaagaatcaa attgctcatc agatatatct
    12901 tttatgatgg tgttttgatt tatacctgct ctgtagcaaa tttctttagc tataataggg
    12961 cttataccta gaaatttaga atatatagac ttaaagatag attcttctga ttcctctagg
    13021 tttttaatga acaaatcctt agatatagca tcaagagggt ttagtttgtt ttgctctgga
    13081 ggtaatgaat aatcatgacc aggtaaaact tgacgaactc tacttatact aaaagggact
    13141 ctttttatag aatctataat tttattttct tcaccatgag ttattattat gttgctatgt
    13201 cttcccataa tttcaatcat aatattttta attgtctttt cctttagttc atctaaagat
    13261 tcaacactta tttttattat tctttcaaaa cctatttgag aaatttctac tatatttcca
    13321 ccttgtatgt attttctaag taacatacaa aacataggtg cttttagagg gttttctttt
    13381 tgataattgc ttgtaagata aactctagga tttgaggcac ttgcactcaa aaccaatcta
    13441 aaattttctt tattatttct tatattaaaa attacctcat catcttcagg ctgatgtatc
    13501 ttatctattt ttccacctgt aagttttgat gataattcat cgactattga atgtataact
    13561 aatccatcta atgccatgta tagcacccct ttctttgacc aaaatgagtc agtaaattaa
    13621 ttatacacat aatatacgct ttgtgactag agggaattta aacaatagag attaatattt
    13681 aaattgtata attatttata cttattagaa aggaaacttt atttttaaaa ttaataattt
    13741 aaagtagatt aaatataaag taaatatagt ataattattg tgtaaagtat aagctatgaa
    13801 agtatatgaa ctttacagaa aaaatcaatt ttaaggttct atagtatata aatatgaaag
    13861 aaggttgaaa aaatgagatt tatcgattta agaagtgata ctgttactat gcctactgat
    13921 gaaatgagag aagctatggc aaaggctcct gttggagatt caatctttag agatgaccct
    13981 actgtaaata aacttgaaga attagcagca gctaaagttg gaaaagagga tgctattttt
    14041 cttccaagtg gaacttttgg taatcaatta gctctattca cacattgtct aagaggacaa
    14101 gaaataatta ttggtaaagg atatcacatt gtaactcatg aggttggggc acctgctgta
    14161 atagctggag ttcagcttag aactatagat gaagacgaaa atggagctct taatcctgaa
    14221 cttgttgaaa aggcaatcag aagagatgac atacatgaac cacagacagg gcttatatgt
    14281 gtagaaaatg catattcagg tggaactgtt gtgggtcttg ataatttaag agaaattaaa
    14341 aaaatagctg agaaacataa cttgccagta catctagatg gagcaagatt atttaatgca
    14401 gcattaactt tgggtgtaga agctaaagaa atagcaaagt gttgtgatag tgttatgttc
    14461 tgtgtgtcaa aaggtttagc tgcaccaatg ggttctatac ttgctggaag taaagacttt
    14521 atagcaaaag ctagaagaaa gcaaaaagtt atgggtggag gaatgagaca agtaggtata
    14581 gttgcagcag ctggtataat tgccattgaa aaaatgactt taagattgaa tgaagaccat
    14641 gaaaatgcaa aatatttagc ttgtgaacta aataaaattg atggcattga agtgaacaat
    14701 gttaatccag atataagtat ggtatttttt aagatgagtg aagatattat aaaagaggat
    14761 gttttaataa aagaattttt tgaaagaaat ataaaaatta ataaaatgga aaatggtgaa
    14821 tatagatttg taactcatgt agatattact aaggaagatt tagactatgt tttaaaaaca
    14881 cttaaagaat taataggtgt atgttaatag atatctacca aaagaattat agctggttat
    14941 cagatgttta attaaaaaat tcatagacag tttaaataaa acatacataa aattcatata
    15001 gaaatattat tatataaaca tagaaagaac tagcttaaaa acataatata attaccctaa
    15061 ttgtaatggc aactctccct cacatcctca aattatagtt gtcattacaa aatttttccc
    15121 ataaattata agtttatggg aattttttta tgttataata gtttaagtgt taatttacga
    15181 aggagcgata cttatgaaat tttggaaact acatggaata ggaaatgatt ttatagcaat
    15241 agatggaaga ttcgaccaga taaacccatc tgattatact gctttagcaa aaaaagtatg
    15301 ccatagaaga ttttctgtag gagcggatgg attgttagtt gtgaaagatt caaaagttgc
    15361 agatgtagaa atggtatatt ataattctga tggttcaaga gcagctatgt gtggaaatgg
    15421 tcttagatgt ttttgtaaat ttgtttatga taattgtata gtcaaaaaag aaagttttac
    15481 agtagataca ttagatggta taaaagatat aaaaataaac cttaccaata gagaaataaa
    15541 ctctataaga gtcaatatgg gaaaaggaag ttttatagct aaggatgttc ctgtacttac
    15601 aaataaagaa cgttttgtgc aagaaagtat aaaggtttta gatagtgagt ttaaagttac
    15661 ttctatgttg atgggggttc ctcatacagt agttatagta gatgagttag atgtagagga
    15721 tgtttgtaaa tatggaaaag agattgaaaa taataaaata tttcctgaaa aaacgaatgt
    15781 aaattttgta aaggtagaag ataagtataa tatacatgtt tatacttggg aaagaggttg
    15841 tgggtatact ctaggttgtg gtactggtat gactgcatca gcaatagtgt gcaatttact
    15901 taatatggta gaaagtagtg taaatgtaac gtctcaaggt ggaacagtta aaatagatgt
    15961 aggagatttc tcttatatga caggtccagc agtaaaaata tgtgaaggta ttttggaggt
    16021 ttaattaatg gctataagta tgactggttt tggaagagga gaatacaagg atgataatta
    16081 ttacttttta gtagagtgta aaacgataaa tcataagtat tcagatataa acatacgtct
    16141 tccaagaaaa atttcatttt tagaggataa agttagaaat ttagtgaaaa attatgtaaa
    16201 aagaggaaga gtagatttat acataaagtt tgacttatta ggcaaagaag atgtaaactt
    16261 aaattttgat gagggattag catctcagta tatagacata ctaaaagaaa taaaaaacaa
    16321 atttgacatt atagatgata ttagtgttat gaatgttgca aagtttcctg atattgtgaa
    16381 aatagaagaa aaggaagaag atgaagattt attatggtca atgttgaatc aagcagttga
    16441 agatgcatta attaaattaa gagaaatgag aagtgaagaa ggtaaaaagt tagctgaaga
    16501 tattgccatg agatgtgatt tattaaaaaa tcatatagaa gaaattgaaa aatattcaag
    16561 tagtgttgtg gaagattata gagaaaaatt gaatttgaga ataagtgaat tactggatga
    16621 cccaagtata atagatgaga atagattagc gcaagaagtt gcaatatatg cagataaaag
    16681 cagtataaca gaagaaatag ttagatttaa aagtcatata gggcaactta aaaatactat
    16741 atttaaagac gactctatag gtagaaaaat agatttctta atacaagaaa tgaatagaga
    16801 gactaacact ataggttcga agtcgtctga tataaatata actaatttag tagtagaagt
    16861 aaaaagcgaa ttagaaaaaa taagggaaca aatacaaaat atagagtaag aatacaatat
    16921 tagaagggga atgcttaaat gtttgtgaaa aaaggattat tgctagttgt atcaggacca
    16981 tcaggtgcag gaaaaggtac tatttgcaaa gaactactta aagaaaatga tacaataaaa
    17041 ctttctgtat cagctactac aagaaaacct agaactggag aagttgatgg agtaaattat
    17101 ttcttcataa gtaaggaaaa gtttgaagag atgatagaaa aaggtgagtt tttggagtat
    17161 gctcaaattt atgataattt ttatggaact ccaaaatcag caataatgga atgtttagaa
    17221 aaaggacaag atgtattact ggagattgaa atgcaaggag caaaacaaat aaaagaagtt
    17281 tgtccagaag gagtatttat atttgtacta cctccatcac ttgaagaact aaaaaataga
    17341 attgttggaa ggggtacaga aacagaagcc gaaatagaga agagatttag ctgtgcatat
    17401 gaagaaatta aaatgattaa ggattatgat tattttatat ttaatgaaga tgtaaaaaca
    17461 tctgctaaag aaatagaagg tataatatca tctgaaaaga ataaagttag cagatataaa
    17521 aatattataa tagagaaatt caaggaggaa ttataattat gttaaaacca tctatcaatg
    17581 aggtactaga aaaaatagac aacagatact atttagtagg gactgtttca aagagagcaa
    17641 gaaaattaat tgatggagaa gagccatatg tttcaaataa agctaaggag aagcctgtat
    17701 gtgtagcaac taaagaagtt gcaagtggaa aaataacata tagattattg acagaagagg
    17761 aaatagagat agaagaagct agacaccatg ctgagcaaca ccaacaaatt tcagaagagg
    17821 agtaaggtca tgctaaaaga taaaactgtt gtaattggca taagcggcgg aatagctgca
    17881 tataaggctt gtgatgttgt aagtaagtta aaaaaactaa atgcaaatat ccatgttata
    17941 atgacaaaat cagcaacaga atttgttaac ccacttacat ttcaatcact gagtcaaaat
    18001 tatgtagtag aagatatgtt tgaagaacca aaaacttggg aagttgaaca tatatcatta
    18061 gcaaaaaaag cagatttatt tttaatagtg ccagcaagtg caaatgttat aggtaagatt
    18121 gcaaatggta tagctgacga tatgttgaca actactgtta tggcaacaaa agcacaggtt
    18181 cttatagcac cagctatgaa tactaatatg tatgaaaatc caattgttca aaaaaatata
    18241 caaactttaa agagctttgg atataaattt attgaaccag aaagcggaag acttgcatgt
    18301 ggagatattg gagcaggtaa actggccaat ccagatataa tagtggagga agttttagct
    18361 aatcttacta aagaacaaga tttaaaaggt caaagtatga tagttacagc tggtccaact
    18421 gtagagagta tagaccctgt aagatattta actaataggt cttctggtaa aatgggatat
    18481 tctatagcaa gagaagctat atctagaggt gctgatgtaa cactaatatc aggtcctaca
    18541 aatctttcta tcccacaaaa tcttaaaaaa tttgttcaaa tagagtcagc acaagatttg
    18601 tacgaagcag tagtatcaaa tttaagtgaa aataaaatag tgattcaaag tgcagcagtt
    18661 gcagattata agccaaaaac ttattctgat aaaaaaatta aaaagaagaa tgatgattta
    18721 tcaatagagt taagtagaaa ttatgatatt gcttatgaaa taggaaaaat aaaagaagat
    18781 aagatactag tgggatttgc agctgaaact aatgacctga tagaacatgc caaaggaaaa
    18841 ataaaaaaga aaaacctaga ttttattgtg gcaaatgatt taactaaaga aggtgctgga
    18901 tttagagctg atactaatat tgtaaaaata atagatgtag aaggaaatat tactgagtat
    18961 cctaaaatga aaaaagaaga agtagccaat gttattttag ataaagttaa agcgttgctt
    19021 gagaaataag acctttttta aatatgatat ttgtgtattt tatcacagct aaagtggctg
    19081 aaagctgcaa tttaatttta gcgagtaaaa actcgcaaat gtcagttaaa ttgtagtttt
    19141 cagcatttat tttgtcataa agtataaaat ataattaata gttaattatt aaaataaagt
    19201 taatattaat aacttggaat tgtttataaa ttatgaaatt ttaatgtctt gtaaagtata
    19261 ttaaaatatg aacagtatat taaatttaag tagaggtttt ataatgaaaa aatatgcaaa
    19321 ggtaatagtt agaagtaata ctatatacac agataattta tttacatacc aaattcctgt
    19381 atttttatct gaggtcataa gaatcggaca cagaatatta gtaccatttg gaaaaggtaa
    19441 taaaccaaca gaagcctttg tatttcaatt tacagatagc ttagatgaaa aaataaaaat
    19501 aaaagaaatt attgatatat tagatgaaaa tccaatattt agaaaagaag atttagagtt
    19561 ggtttattgg atgaaaaata gatatttgtg cacttatata gaatgtataa atttgatata
    19621 tccaaaggga tacaaactaa ataattataa agtagtccta ttaggtgaaa gtttaagtgg
    19681 attaaatgat attgaattga aggaaaaaat atcaacttta agtgataaaa atagagaaat
    19741 agtagaaaaa gtgattgaga gtaaaggtaa aattaaggtt gataagttaa aatatatacc
    19801 aaacttaaat agttctttgt acacaatgaa taaaaatgga attataaaat tatgttggga
    19861 atataaaaat cacaaaaatg aaaagaaagt atgttatata tctttgagtt tggaaagtga
    19921 taagattgat gattatatag agcaaaataa aataaatgta ggaagtaaac aaaaagagat
    19981 attaagtttt cttaaaaata atgaaaatgt agagataaat gatttattgg atttattaaa
    20041 tgcttcaaaa caaagtataa attctctaag caagaaaaaa ctaataacct tagaatttaa
    20101 ggattattat agagagccaa aaagtattta caaatccgtg ttaaaaagta taaaattaaa
    20161 caatgagcaa caaaaagcag ttgatgaaat aaagtcgaat atgtttttag atgataaaaa
    20221 accatactta attcatggag taactggaag tggaaaaact gaagtttaca tggaaataat
    20281 agaatttgct ctaaatcaag gcttagacag tatattctta gtacctgaga tagcattaac
    20341 tcctcaaaca atagataggc ttaaaagtag gtttggagat ttagttggtg tgtttcacag
    20401 caaactatct gaaggagaaa aacatgatgt ttataaggct gtcaaggcag gtaaagtaag
    20461 agtgttaatt ggagctaggt cggctttatt tgcacctttt aattctttag gcttaataat
    20521 aattgatgaa tgtcatgagt catcatataa gtctgagaag aatccaaaat ttaatgctat
    20581 agaagttgct agatttatgg cattaaaaaa taatataact cttattttag gttcagcaac
    20641 accatcaatt gaagagtatt atagggcaaa atacggagaa tacaaactta taaatataaa
    20701 gagtagagca aatgacaaac ctcttccaaa tattgaagta gtagacatga aagaggagtt
    20761 agataaagga aatagaagca tatttagttt gaaattacaa aaagaaatac gttgtgcgat
    20821 tgaagaaaat aatcaagtaa tactgttttt aaatagaaga ggttatgcaa attttgtatc
    20881 ttgtagaaag tgtggatatg tgtttcaatg tgaaaattgt gatatatctt taacttatca
    20941 taagaaaagc aatactggaa gatgccacta ttgtggatat gagaaagaaa ttccaaaaga
    21001 gtgtcctgaa tgtaaaagta cttatgttaa gccatttgga gttggaactc aaaaaatcga
    21061 ggaggaatta aaatatattt ttccagatat aaaaactttg agaatggata aagatacaac
    21121 ttcaaaaaaa ggtgctttag atgatatact aaataaattt aaagataaaa aagcagatgt
    21181 actaattgga acacagatgc taagcaaagg gttggatttt gagaatgtaa ctttagtagg
    21241 gattttgtct gcagacatga tattaaattt tccagatttt aaaagttttg aaactacatt
    21301 tcaattgata actcaagttt ctggaagagc tggaagagct gataaagaag gaaaagtagt
    21361 acttcaaact tatgatactg aacactatgc tattaagcat gctattgaat atgattatga
    21421 aggtttttat gaagatgaga taaaaataag aaaagcattt ggatattctc cttttaataa
    21481 catgttaagt gtagttgtta gtggtgaaga tgagcgattg gtagtaaaaa atataaaaaa
    21541 tatgcatgca tctttaattt atttattaga aaaaaggggt ataaatgatt taggatttat
    21601 attaggtcca aacccatgtt caatatcaaa aataaatcaa aattatagat ggcaaatact
    21661 ctttaaagac gaaaatattg aaattaatct cttaaagggt ataataaaat atatatgtat
    21721 aacaaaacga gatttgatat ttgataagaa tatcagtgta tctatagata ttaatccaaa
    21781 cagtgtatta taaatttagg aggaattata atggctttaa gacaaatagt tcaaatagga
    21841 gaaccagtat taagaaaaaa atcaaaaaag gttgaaaaaa ttgatgaaaa gataatacaa
    21901 ttattagatg atatggcaga aactatgtat gatgcagatg gcgttggatt agctgcacca
    21961 caagttggaa tcttaaaaag agtagtagta atagatattg gagaagagct tatagaactt
    22021 ataaatcctg aaataataga aacatctggg gagcaaatag atgaggaagg atgcttaagt
    22081 gttgttggag aagcgggaaa tgttagaaga ccaaattatg taaaggttag agctttaaat
    22141 agaaatggtg aaacaataga gttagaggga gaagaacttt tagctagagc attttgtcat
    22201 gaactagacc acttagatgg aattttattt gttgacaaaa tagaaaagta gtaggagttg
    22261 atttaatgaa aatagtattt atgggaactc ctgatatagc agttccatgt ttacaaaaaa
    22321 taatagatga gaagtatgaa atattgggtg ttgtaactca accagataaa ccaaaaggaa
    22381 gaggtaaaaa actgggtatg agtccagtaa aagaactggc aattgaaaat aatatacctg
    22441 tatatcaacc agtaaaggct agagataaag aatttataga tacaattaaa tctttaaatc
    22501 cagatgtaat agtagttgta gcttttggac agatacttcc aaaaggaata ttagagattc
    22561 ctaagtttgg atgtataaat gttcatgttt ctttacttcc aaaatataga ggtgcggcac
    22621 ctataaattg ggtaataata aatggtgaag aaaagactgg tgttacaact atgtatatgg
    22681 atgaaggtct agatactgga gatatgatac taaagacaga agtaaacctt gatgaaaata
    22741 taacagcagg agaacttcat gataaaatga tgaatatagg agcagagact ttaaaagaaa
    22801 cattaagatt aattgaagaa ggaaatgctc caagagaagt acaaaatcat gaagaatttt
    22861 catatgcccc aataatgaat aaatcattag gtaacataga cttttcaaaa agtgctaggg
    22921 aaatacacaa tttagttaga ggggtaaatc catggccaag tgcttatact acctataatg
    22981 atgtcataat gaaagtttgg aaaactaaag tgttagatga gaaaagtaca aaagatgcag
    23041 gtacaataat tgatgtaagc aaagatggaa taaaagtaag tactatagat aatgtacttt
    23101 taattgaaga aattcagatg ccgaataaaa aaagaatgtt ggttggtgaa tatataaaag
    23161 ggaatactat agaaactggt ttagtattgg gttaggtgaa aagtatgaca gatataaaga
    23221 agtatttaac aagtgttggg attttgattt taatattagg gcttttgata ggagttgtta
    23281 atttttttat aataagttta actcaaatat tttccttaat aataaatatt ataataatat
    23341 cactaatact tataatacta tgttcaacag cagttactta tagagtaatt aaaggaaaga
    23401 atattaactc aaatataatg aaaataaatt ttaatattgt tagtggatta tttcctatta
    23461 tatcttttat tgcatcatca tttggtatgt caaaaagtga gattagaaga atatatataa
    23521 agttaaataa tgaatatata tacagtaata aatataattt taatccagag gatataataa
    23581 ttttaatacc tcattgtatt caagagaata gttgtaaatt aaaagttact aatgatatag
    23641 ataattgtga agaatgtgga agatgcaacg taggagaatt aattaagcta aaggaaaaaa
    23701 ctaatgtaaa aatatttgta gctacaggag gaacactagc tagaaaaatt ataatagaca
    23761 ataaacctaa agctgttgta gccgttgcat gtgaaagaga tttgacatct ggaatacaag
    23821 atattaaaaa aattcctgtt ttaggtgtat ttaacaaaag acctaatgga ccttgtgtaa
    23881 atactaatgt agatatgata gacattgaaa aggctataga atttttaaca ggaaaaaata
    23941 tattagcttg taattaaact gtttttaagt taagtgaata ttaagaggat gtataataaa
    24001 aatatatttt aggagagtgt tatttatgta ccctgtatat ggcggttttt ggggatttga
    24061 cccaacaatg gttgtattaa ttccagctat attacttact atatatgcac aatttaaagt
    24121 gagttcaaca acaaacaagt atttaagagt aaatacacgt cgaggatata ctggagagca
    24181 aacagcaaga agagtacttg attcaaatgg tttgtatgat gtaaagatag aaatggttag
    24241 aggacatcta agtgaccatt atgacccaag aagaaaggct gtaaggttgt cagaagatgt
    24301 atattatgga acatctataa cttctgttgc agtagctgca catgagtgtg gtcatgccat
    24361 acaacatgct aaaggttatg cacctcttca aataagaagt agtttagtac cagtagtgaa
    24421 ttttgcttca agtatatctt ggtttttaat atttctagga tttattatgg ctggtccatt
    24481 tttaaaaatt ggtatactat tgttttcggc ttcagtgtta ttccaaataa taacattgcc
    24541 tgtagaattt aatgcttcaa gtagagcaat agttcaactt ggaaatttag gtattataga
    24601 tgagagtgag tcaagacaaa gtagaagagt gctttcagca gcagctttaa catatgttgc
    24661 agcagcattg gtttcaatac ttcaattact tagattgtta ctaatagctc aaagaagaaa
    24721 tgactaaaag taaagtgggt tgtttagaaa caaccctttt ttatgtttaa taaaagggag
    24781 aaatttatat ggatgcaaga gaagttggat ttaaggtatt atgtgatata gaaaaaaata
    24841 acaattattc aaatattgca ataaataagc attttaaaaa tttagaaata agtgacattg
    24901 atagagggct tgcaacagaa ttaatttatg gagtaataga aaataaatat tatttagatt
    24961 atataatcaa taaactttca aaaataaagg taaaaaaaat gtcaacttat gttaaaatct
    25021 ttttaagaat gggaacatat cagattttgt ttttagatag tatatctgat tatgcagcag
    25081 ttaatgaaac tgtgaaatta tctaagaaat atgataaaaa atcttctggt ttcataaatg
    25141 ctattcttag aaatgaaata agagctaaag agactataat ggacataact gaggaagata
    25201 gtgtaaaata cctatctata aagtattctt ataactcttg gattataaaa aactggatag
    25261 ataaatttgg acaagaattt gctgaagatt tattggaagc gaatagtgaa aagcctagta
    25321 tctatataag aacgaatatg cttaaaataa gtcgagaaga acttattgaa aaattaagtg
    25381 aaatgggtat tgtatgttta aaagttccta tggtagaaga agctattaaa gtcgaaaaaa
    25441 tgaaaaatat agaaaaaaat gaattattta aggctggttt atttacaatt caagatataa
    25501 gttctatgat agtagggaaa gtaattaatc caaaagaaga ctcatttgtt ttggacgtat
    25561 gtagtgctcc tggaggaaaa tctactcact tagccacttt aatgaacaac actggtcaag
    25621 tagtagctag agatattttt gagcataaac taaaacttat aaaatctact gtaaacagat
    25681 tgggacttaa aaatgtatgt gtagaaagat ttgatgcttc tgagattgat gaaaatagta
    25741 taagtaaatt tgattatgtt ttagcagatg ttccttgctc tggtcttggt ataataagac
    25801 gtaaaccaga gattaaatat aagaaagaag aagagttaaa agacatcact tctatacaaa
    25861 agaaaatttt agaaaatgca tccagatatg tcaaagttgg tggaacttta gtatatagta
    25921 catgtacaat tcaagatgat gagaatataa atatagttgc ttcttttgtt gaagaaaatc
    25981 acaactttga atttgattcg attgatacag taaatgtaga tttagataat caagataaag
    26041 gatatttaaa gatatatcct aatattcatg gtatagatgg ttttttcata gcaaaattaa
    26101 agagaataag gtagtgagag aatggaaaag aaaaagatag tattaaaaaa ttttactgaa
    26161 gatgaactta aagaatttat gaaaactata gatgaaaagc cctttagagg aagccaaata
    26221 ttctcttgga tatataaggg tgcaaaaact tttgaggata tgaataatat accaaaaagt
    26281 ttgagaaata aattagaaga aatttcatgt ataggtcata tagatataga attaaagtta
    26341 gaatctaagg tagataatac aaaaaaatat ttgtttttat tagatgatgg aaatataata
    26401 gaaactgtga tgatggatta tgatagtaga gttactgtct gtgtctctaa tcaagtaggt
    26461 tgtaggatgg gatgtaattt ttgtgcatct acaatggatg ggttaattag aaacctagag
    26521 ccatgggaga ttttagacca agttattaaa attcaagaag atactggtaa gagggtatca
    26581 aatcttgtat tgatgggaag tggtgaacca cttgataact ttgaaaatac aaaacaattt
    26641 ttaaaaataa ttaacgaaaa aaatggtctt aatatagggt atagacatat aactctttca
    26701 acttgtggga tagtacctaa aatgtatgag ttggcagatt tagaaatagc tataaattta
    26761 gctttatcac ttcattcacc atatgatgaa gaacgaagaa aaattatgcc tgtagcaaat
    26821 gcttattcta ttaaagaaat attagatgca tgtagatatt atataaaaaa gacaaataga
    26881 agggttacat ttgaatattc tcttataaaa ggggtaaatg actcagaaaa agaagcaaag
    26941 gcattagcta agctcctaaa aggtatgcta tgtcatgtaa atttaattcc aataaataaa
    27001 gttgaagaaa gagaatacga aaagccagat aaagcattta tttataaatt tagggatagt
    27061 ttagagaaaa acaatatacc tgccacagtt aggatgtcta tgggttctga tattagtgga
    27121 gcttgtgggc aattgagaag aaaatacaag taatttgtaa ggaggaagtc gtatggttta
    27181 tagttgtgcc tcccatatag gaaaaataag aaaaaacaat gaagactatt gtgagggaga
    27241 agttatagat acagaacatg gtccaatagg aatatttgcc atagctgatg gaatgggtgg
    27301 acataaaaaa ggtgaagtcg ccagtaaatt agcagtagaa aatataattg attttctaaa
    27361 agaaaactta ttacaacatg ataatgtaaa aatagactat atagatgata tattaaaaca
    27421 ggcttataat aatgtaaact caattgtgca caaaaaatct atggaagata tagaatttga
    27481 aggaatggga actacattag ttacagctat agtgtataat aatgtcttat atgtggcaaa
    27541 tgttggagat agcagatgtt atttgttaac agatgaaaaa tttgataaaa taactataga
    27601 ccattccgtg gttgaagaac ttatgatggc tcatgtcatt acagaagaag aggcaagaag
    27661 acatccacag aggaatagaa taactagagc aattgggaca gatgatatgg ttgttgtaga
    27721 tatttttaag aaagaaatca aaaaaagtga tataatactt cttgcgacag atggattaac
    27781 tgggtttatt gatgatgaag atataagaga tttaatatta gattatgaat atgagagaac
    27841 tagtaatata agtgaagaat tgataagtat ggccaatgat gtttctggta aagataatgt
    27901 ttcggttata gtgataaaag tataattagg acggtgatat tgtgggagat acaattttag
    27961 gaaatcgata tgaaatcatc aggaagattg gtgatggagg aatggccttt gtatatgagg
    28021 ctaaagacag attattaaac aggactgttg cacttaaagt acttagacct gaatttgtag
    28081 atgatgatga atttttaaca aagtttaaaa gagaggcaga ggcagtagca agtctttccc
    28141 atccaaatat agtaaatgtt tatgatgttg gtgaagatgg aaaggttcac tacattgtaa
    28201 tggagtttgt agatggaaaa aatctaaaag agattataca agatgaaggt atattagatg
    28261 aatatactgc attagatata acaaaacaaa tagctatggc acttagtgcc gcgcacaaaa
    28321 aggggattat acatagagat ataaaacctc ataatatcct catatcgaat gaaggaagag
    28381 tagtaaaagt ggctgacttt ggtatagcca aagctgtttc aaattcaaca atgactaata
    28441 ttggtagtat aataggttca gtgcattatt tttcgccaga acaagctaaa ggtaaatttg
    28501 taactaataa tgctgatttg tattctctag gtatagtttt atatgaaatg ttgataggaa
    28561 aagttccatt taggggagac agtccaattt ctatagcact tcaacacatt aatgatgata
    28621 tagactttac atcagaagaa aaagttagga ttcctcaaag tgtaagaact acaataaaaa
    28681 agcttacaga aaaatctagt gcagatagat atcaaactgc tgaagaattg atagaagata
    28741 tagagtatat agaaaaaaat attgatttag attttataaa agaatatgat gattttgcaa
    28801 ctaagaaaat tgatgaaaag gaaattaata aagttgtaaa tccaatactt gcaaaaccag
    28861 cccctgaaaa agtggttaag cctgttgaag tagctgattt ggatgatgat gaagattact
    28921 atgatgattt ttatgaagaa gatgaagaag aggaagagat aatgagagct aaaaagaatc
    28981 agagaactaa aagtgctcca agtaagagaa ctaagaaaaa gaagaaaaaa caggaaagcc
    29041 caaaatctag aagaagatta aaagtaattg caactgtttt gatattgata ttgtgtgctc
    29101 aagtattctt agcatataag tttttatttt ctggagggtt tggcaataaa tctttgactg
    29161 ttcctaatct tgtaaatatg acattagaag aagctcaaag tgctgttgaa aaagaagggt
    29221 tatacctaag tgtaaaaagc gaagagtata atagtgaagt tgatgaaaat tgtataatat
    29281 cacagacacc tgaaggtgga agtacaaata tcaaaaaggg tgatactata aatgttgttg
    29341 taagtaaagg ttcaagtcag gcatcggttc caaatgtagt gggacttact ctaagtaatg
    29401 caaaacaact tattgaagaa aataacttaa aagtgggaac tgttaagtat gaatatagtt
    29461 caatatataa agaaggaaca gttttaaatc agagtccagg agctggttca tcaagagtgc
    29521 aagaaggtga cgagataagt ttatatgtaa gtaaaggttc agaaaaatca aatacacaga
    29581 ctccaacagt accaaataaa acaccaacaa caccaaataa tgatacacca acagaacctg
    29641 gttcaaactc aggaagtagt ggaggaagct caggaggttc aaattcagga aatagtggag
    29701 ggaactcagg aaataatgga aacaactcag gaggttcaaa ctcaggaaat agtggaggga
    29761 actcaggagg ctcaaattca ggagacaatg gagggaactc aggaggctca aattcaggag
    29821 acaatggagg gagctcaggc ggttcaaact caggagacaa tggagatagt tcaggaggct
    29881 caaactcagg agataatgga ggaacttcat caggcactgg tgcaaatatt ggtaaaacag
    29941 aataaatatt aataaaataa gagctgtcct tttatagaaa atattttctt taaagggcag
    30001 tttgttttgt ataaaatatt gaattggtta taatataagg agaaaagcat ttatgaaaaa
    30061 gaaaacagtt ttaattacag gaggagctag aggaattggc aaagctatgt ctaaagcttt
    30121 tgcaaaagaa ggttataatg tattagtaaa ttttaataag tcagaaaatg aagctaaaga
    30181 gttgtatact agattaaatg aagaaaattt ttctataaaa ctttttaagg ctgatgtttc
    30241 aaatagagaa gatgtagaga atatggtaga ttattgtata aaagaatttg gaggattgga
    30301 tgtacttgta aacaatgctg gtataagtca agacaagttg tttacagata taactgatgt
    30361 agactgggat aatatgatga atattaattt aaaaggaagt ttttattgtt cacaagttgc
    30421 tttaaaatac atgatatcag aaaaaaaagg aaatataatt aatatatctt caatctgggg
    30481 tatatcaggt gcttcttgtg aagtgcatta ttctataaca aaagcaggta taataggaat
    30541 gacaaaagca ttagctaaag aagtaggacc atcaaatatt agagtaaata gcatagctcc
    30601 aggtgtcatt aatactgata tgttatctgg atataatgag gaagatatag atattcttgt
    30661 ggaagaaact cctctaatga ggctaggaac tccagaagat atagcaaatt gtgctatttt
    30721 cttggcatca gacaaatcaa attttataac tggtcaagta attagtccaa acggaggatt
    30781 tgttatttaa aaaaaatgtg gtattatata aaaataggaa agaataacac gatatactac
    30841 tcataaacag tatgtgttta tataaatttt ataaagggag gcatttgatg ctagaaggaa
    30901 aaattataaa ggggattagt ggattttatt atgtagatac gcataatggt atttatgaat
    30961 gtaaggctag aggaatattt agaaaacata aaataacacc tctggttggt gatagagtca
    31021 aaataagcat tgttgatgag gatgaaaaaa aaggtatctt agaagaaata gacagtagag
    31081 atacagaact tataagacct cctatagcaa atgtagataa ggcactaata gtattcgcaa
    31141 taaaaaatcc taaaccaaac ttatctcttt tagatagatt tatagttttg gcagaaaaag
    31201 aaaatttaga aactgtaata atccttacaa aagcagattt agatgataat gatacactag
    31261 aaactgttaa aaaaatatat gaacttagtg gatacaaagt tattcctgta agcaatatta
    31321 ctaaattaaa tatagagaaa gtaaaagaag agttaaaaga aaatgtagta gtgtttgcag
    31381 gaccatctgg agttggaaaa tcaagtttac taaatgaaat agatgaaaac tttaaacttc
    31441 aaacaggagt ggtaagtgat aaaataaaaa ggggaaaaca tactactcgt catgctgaac
    31501 ttttaaaatt ggaatttggt ggaatggttg cagatacacc aggctttagt tctcttgcac
    31561 ttgaagatat agaggaagtt gaacttaaag attattttat agaatttgat aaatttaatg
    31621 attgtaagtt tggttcaaaa tgtattcatg aaaatgaacc taattgtgct ataaaagaag
    31681 ctgttgcaaa tggagaaata tctaaagaaa gatatgagag ttatatacag ctactaaatg
    31741 aaataagaca aaataatagt aggaggtatt agaaacatga ttaaattagc accatcaata
    31801 ttatcagcag attttgcaaa attattagag gatgtaagaa aggtagagag tgcaggatgt
    31861 gaatatcttc atatcgatgt aatggatgga cactttgtac caaacattac attaggacca
    31921 cttgtagtca aaagtttgaa gaaagaaaat ataaatatgg tatttgatgc tcatcttatg
    31981 atagaaaatc cagaccagta tattgaagag tttgtaaaag caggatgtga tataataact
    32041 gttcatcaag aggcttgtgt tcatctacat agaactatac aaaatataaa atcacatgga
    32101 ataaaagcag gtgtagtgct taatccagct acaccaatag atactattaa acatgtacta
    32161 cctgatttag atatggtatt attaatgtct gttaatcctg gatttggagg acaatcattt
    32221 ataccttgtg ttttagataa gattaaagag ttaaaagcta ttatagatag tcaaggatta
    32281 aatattgata tagaagttga tggtggtata agccctaaaa atgtggataa agttgtacaa
    32341 gcaggagcta atgtaatagt agcaggttct gcaatatttg gaagtgatga cattcaagaa
    32401 acagttaatt tatttagaaa gaatgcttct cttgaagaat tagtttaaat ttaagaatga
    32461 aaatctgtat tgttttaaat ggtgaaatag aagattacga agttacaaga ggtattataa
    32521 ttaaagaatg ttatgactgc ataatatgtg cagatggagg agcaaatcac acttataaaa
    32581 tggaaataat gccagattat atattaggag acttagattc agtagaagaa gaaaagataa
    32641 acttctataa aaataaaggt gttaaatttg aaaaatttcc atctaaaaaa gatgagactg
    32701 atacagagct ttgtcttttt ttagctaaga cacttaaagc aaatcatatt gatttttttg
    32761 gtgctttagg aggtaggatt gaccacactc ttgcaaatat aaagctatta tattatttaa
    32821 aagaagatgg tatatattct aggatacttt ctgataaaga agagatgtat atagttgaaa
    32881 atgaagaaat ttcactgtat ggaaatccag gagacactat ttctgtaata gctataaaag
    32941 gtgatgctaa gggtgtaaca cttaccggat tagaatatcc tctcgataat tattatatga
    33001 gatactctgt acctattgga atatcaaatg ttatgttgag taattcttgt aagattaaag
    33061 tagagcaagg atgtgtactt gtagttagaa atttataaaa tttggttttg acaattgatt
    33121 ttatattgta gagcagatac aatcaagtaa aatatattta tgattgtatc tgctttttag
    33181 tatataatta taaatagata ataaactttg acataagggg gattttttgt ggtagatagt
    33241 attatttttg atttagatgg aacgttgtgg gattcaactg aagaagtatg caaagtttgg
    33301 caggatgttt taagtaaaca taaagaaata gatttaagtg tcacaaaaga tttatttaga
    33361 agtcttatgg ggctttcttt tgaggaaata gcaaatcgtt tatttccaaa tttaagtgaa
    33421 gaagaaagaa ataatttatt aaatgaatgt tctttgaaag aatgtgaata tttatctgaa
    33481 aatggagcta aattatttga tgatatagaa aatactctta aattactatc taaaaaatat
    33541 aaattattta tagtaagtaa ttgtcaagct ggatatatag aatctttttt aaaagcacat
    33601 aaactagaac agtattttgt agattttgaa tgtccaggta atactggttt gcataaaggg
    33661 gaaaataata aacttataat tgaaagaaat aaattaaaaa acccaatcta tattggagat
    33721 actcaaggtg atgcaaatag tgctaagttt gcaggtatcc cttttatata tgctaaatat
    33781 ggatttggga atgtagatgt atatgattat tttatagact catttaaaga tttgttagaa
    33841 catgatatat taaaatagga tgagtttaaa aattatatta aaataataaa aaagttatgg
    33901 ggggatttaa aaatggaatt acaggatact atttttaaaa gacaaagtgt aagaaagttt
    33961 aaaaatcaag atgtgtcaga tgaagatatt ttaaaaatga taaaagcagc aggtgcagct
    34021 ccatcaggaa agaatattca aaactggcat tttgtcatta taaaacgtcg tgacttaatg
    34081 gaaaagatag cagatgtgat aactaaaaag caacaagaaa tacttgtaga aatggaaaaa
    34141 gtatcagtag ataaggctaa tagatttaga aaatttgtta aaaactttac actattttac
    34201 ttaaaagctc cagttttagt attagttttt acaaaggtat ataatccatc aggatattat
    34261 gaattagagc ttatagatgc acctaaggaa actatagata aattattcat aagaaatcca
    34321 ggtatgcaga gtttaggtgc tgcgattgaa aactttacat tatcagcaat tgaacttggg
    34381 tatggttctt gttggttgac aagtcaaaac tacgcagcag atgaaataga agctgtttta
    34441 gaagcagaaa ctggatttga aaaaggagag tattttttag gtgcaatgtt ggctcttgga
    34501 gtgccagagg ataatttgaa gagcccatct aaaaaaccag tagaagaaat atgtacattt
    34561 ataaaataaa agacaataat ttttaagatt caaaatgagt taaaaataaa tagttaaaaa
    34621 taaaaaggta ggttttattg atattaagtt tatgtttcaa atcattgatt taattaatgc
    34681 aataaaaact accttttttg tgcatattaa ttttgaataa ctccaaatct ttagaaaatc
    34741 tttagaaaag tatatgtaat atcttaagtt tttaacttta atattaagta tataaaatga
    34801 aaaaactaaa tttatactag agggaggtct ctaaggtgta cattaaataa aaataactat
    34861 tagaaagata taaatatata aaaaaatgga aaaacttcta tcatattgta taatcatata
    34921 tgtaaagaaa atttataaat taattggtat aaaggagatt aaaatgaatt catataatat
    34981 tttggtggta gaagatgaaa aggaaatagc agatgctata gagatatacc tattaaatca
    35041 aggatataat gtttttaaag gatacaatgg attagaagga cttaaggtta tagaaaatca
    35101 agaaatacat ttagcaataa ttgatataat gatgcctaaa atggatggaa taacacttac
    35161 aatgaagctt agagaaaatc ataatttccc agtaataatg ctatctgcaa aatcagaaga
    35221 agttgataaa ataatggggc ttaatatagg ggcagacgat tatgtaacaa aaccttttaa
    35281 gcctttagag ctattggcta gagtaaactc acaacttaga agatacacta agtatttaaa
    35341 tatggttgaa aataaagagc aaaaagtaga tgatgatgat ggcgtgtttg caataggtgg
    35401 attagaatta aatgaaaata caaaagaagt tagtgttgat gggaagcata taaaagcaac
    35461 tcccatagaa tttaaaatac taagcttact tatgagaaat gcaggaagag ttttttctgc
    35521 tgatgaaata tatgaaagag tttggaatga taatgctgta aatacagata cagttatggt
    35581 acatgttagg aatataaggg agaaaataga agtagaccca aaaaatccta aatatttaaa
    35641 ggtggtgtgg ggtgttggat acaaaattga aaaaattcaa agataaatat atagttacta
    35701 ttatagtttt tatacttatg ttatcagcat cattaggtat gattagtcaa tattctacta
    35761 ttcaagcagg ggctaaaggt ggagcaaaga atccatttga acaggaaagt tttgtagata
    35821 atatgtataa aggaagttat gttttatatc ataacatgaa agaagaacaa gaaggtaaga
    35881 tgatacaacc ctcaaaactt tttataagta aagaaactat gaactatata aaaaatgtaa
    35941 gtaaagaaaa agatacttat gatggctcag agacttatta tacagatgat agtattaatg
    36001 cagattttaa tcaaaacttt gaaaattggg agtcttttat taaagaatca ggaaaaaatt
    36061 taaaatatta tttagttgat aaagaaagta actttgaatt ttttaacgat aataaagaat
    36121 taggagcact tgatacaaca aagaattatg cttcaaaaga agattctgat gaaaataaat
    36181 caaaaaatac agaaatgagt gatgaggaaa gacaaaagca gattaaagat ataaaggaaa
    36241 actatagatt ctacattgta atgaattttg ataaagatgg aaaagtaaat gttttggatt
    36301 cttatggagt aaatcaaaaa gttattagtc aaatgttatt gtctaaagca agagaagatt
    36361 taatgaatac aactttaggt ggaaatccaa tttcatataa gctatctcca ataaaaaacg
    36421 tgacattagt atatgcagta cctaaggtaa taagtaaagg ggatggtgga gagtatagtt
    36481 atggaaatat ttataataat gatagtataa gttcatatat aaataatgta gaaaataatt
    36541 cttactataa gatttctgga atgattttaa aaattatatt agctatagtt gtgattgtag
    36601 ctttagcatt cccatataga aaatctaaag aattactagg atttgataca ttatcaagaa
    36661 taccattaga gatattattt attattcttg ctattttaca aggaattgta gatttatatc
    36721 ctactagtat aataagtaat actttgagtg gaaattatgt agaatatctg ataaacaatg
    36781 acataagtgc taaaatggct agtatattgg taagtttaat gaatctaact tattggtttg
    36841 taatattctc aataatattt gtatttataa tacttttaaa acatatttta aatgttggaa
    36901 taaaagagta ttttataaag aatactgtca caggaatgtt ttttgtatgg ttgataaaat
    36961 caggaaaagt agttattaat caaattagaa taacagattt aaaagaaaag cctaataaaa
    37021 ctatagctat aattttggga ataaacttat taattatagt tataatgtgt agtttttggt
    37081 tctttggaat aatacttgca ttgatatatt cagtagtatt atttaagata ttgtcagatt
    37141 actctaaaaa gacaatatat gaatataatc aacttttaga tgttacaaag aaaatttcag
    37201 atggaaactt agaagtaaat atggaaagag atttaggatt ttttaatcct ataaaagatg
    37261 aattaggaaa tattcaagct ggatttaaaa aagctgttga tgaagaggtt aagagtcaaa
    37321 agatgaaaac ggagcttata tcaaacgtat cacatgacct aaaaacacct ctgacatcta
    37381 taatcactta tatagattta ttaaaagatg aaagtataac agatgaaaat cgtaagttgt
    37441 atattgatac attagataga aagtcacaaa gattgcaaca tctaatagaa gacttattcg
    37501 aagtaagtaa ggtaaatagt ggagatgttc atttgaacat aatgaatgtg gatattgtgt
    37561 ctctaatgaa acaaacactt ttagaattag atgacaaact tgcagattca tctctaatag
    37621 taaagaataa cttttctaat gaaaaaataa tattaccatt agatagtcag cgtacattta
    37681 gagtatttga aaatcttata ataaatataa gcaaatatgc aatgccaaat tcaagagtgt
    37741 atattgatat tttagaaaca gacaataaag taagtattat gcttaaaaac atgtctgcaa
    37801 ctgagattga ttttagtgta gatgatataa tggaaagatt tgtaagagga gataagtcac
    37861 gcaacacaga aggttctggt cttggtttag caatagcaaa aagttttata gaattacagg
    37921 gtggtaagat gaatataagt gtggatggtg atttatttaa agttacaatt acttttaata
    37981 aaaattagaa tagacttctt taataattat aaaatccata aaataatatt ttataggtat
    38041 tgttttaaag tagtttttaa acattatttc aaaacaactt gtaaatctta ttttaaaata
    38101 gaatgttgat ttatttaaaa aaggtgaatc ctaatatata agattcacct ttttatttta
    38161 taaaatgtta cttagtgtta tagatatttt aaatagtgta aatttggatt taccattaac
    38221 ataaggttag taatttcttt tgaaatcttg tataagctat tttatattat ttaattacta
    38281 ttgtttgtac tttacaatgt gacaaagaat ttacttctac agttttagta tttaccttaa
    38341 gcttgttagt attatcatag atttcgtcaa gcattgcatt ataagcagca ttgatatttt
    38401 tattgatgtt aagacttcct ttagaatcct catttttcat accattgaag attctaacta
    38461 caattccgtc tcctttttct tctttcttta ttgcacttac tgtgaaattt gaattattta
    38521 cattcataaa actatattca ttttcatata tttgtttttc atcattaaat acaaatataa
    38581 gtctaccatt taaaaaatca gcatattcat atatttgtat aggtgttaag aatctcttag
    38641 cagtattagc tatatttgat ttatcaaatt tattgttgta gatgtaaaga ccaaagttaa
    38701 agtttaactc tttgagtaat tgtgcatctg gtgttgctat tattttttct ccagaagctc
    38761 ttcctggtct ataaagtaaa ttttctcttc ccatatatcc aaatgaccta aatagtgtta
    38821 atgctattgt atctaaatta gcaccaacta tttgatattc tctcacacaa ccagttatta
    38881 atgctactcc tttttgtcca tcttctaaag taacaaaact ttgcattggt tcaatagtta
    38941 taggcttttc ttgccatgag taattgtctc ttttccataa tgcaaggtct ttttctaatg
    39001 ctgttggtct ttgtattatt ccaaattgtt gatctgctat agaaaactta gatgctattt
    39061 ccgtattaaa taaaactctt actctatgag ataatgcttg gtcatttttt atattaatat
    39121 taaacttaat tatttgctct ttaggttcta aggtgatttt cattgttact ggcattttca
    39181 cagaaacttt acctatagtc ctttcttcta gtgaagctgg tatggtcaat gaatatttaa
    39241 gtgtcatttc ttcttgaaca tttgatttta gcacttctac tgaagataca gaatctaaag
    39301 atgaaacata aatatctttt cttggaggcg aatagttgta tgaatctcca tcatctccat
    39361 tatcttcaat tacagcttgg tttttataag tcttattaga ctctttatct aatatttcta
    39421 ctgaaccatt tttattggct gttattttat agtatttgtt ttctattttt ttacaactac
    39481 ttgtttttat ttcacattta tttttagtat ctaattcaac aattagctga gtatatccca
    39541 tgggtggtat attttttact gaaagtgcaa tttttgccct atatacagtt tttggtatat
    39601 atattttttt acttgggttt aattttattg tttgagttaa tatataatct gtaatatctt
    39661 ctttttcttt tattatataa ttaagaattt ctccattttt gttctttatc acaaaatctt
    39721 gacctggaat ataagtatca aattctacaa cttcatttct agcttctggt aatccattga
    39781 atactgttaa tgttatttct tcattattat ttttgatttg agtacttata agtctcatat
    39841 gaaaatctaa caaatttata ctcaaatctc tggcttgttt gtatcttgtg tatacatctt
    39901 catttgttgt gtcactatta caagaaccta tgctgtcatg agctgcattt tcgaacataa
    39961 gtttccatat atcttttaaa attaggtgag ggtattcatt tccaagtgaa taacttaatg
    40021 ttaataatgg ttcaagtaca tttgtaatat aattttctaa tttattattc attatcttaa
    40081 ggtctgacct tgaggagaat attgatttgt gtattctcat atgtttagca tttacaaatt
    40141 cacctttaag ctctgtaaat tcatttcttt catttcttac tgaatctaca tagttttcta
    40201 tatcacttat ttcgtattca ttttcagtat ctattttatt agcttttttt aatatgtcag
    40261 gaaggttttt tcttattggt gcttggtcaa atccatttgg gaaatatacg ttattagtag
    40321 aggatttaac cttaagtttt ccaattgtat cttttaaata ttcttttaaa tctgaatcat
    40381 cttctggtat attacctcca tagtaataac caaatggtat ttgaactgct aatacctttg
    40441 agccatcaga acctttccat ataaattctg ttgtatctac catatcatca gaaactccac
    40501 gccaaaataa tgaactatct attccaaaac ctctatatat ttgtggcatt tgagctgatt
    40561 gtccaaaaga atctggtaca tatccaaccc tcataggttc gccaaattca ttgcatctat
    40621 ctattccata gtaaaggttt ctaactatag attctcctga tataaccaat tggtctgttt
    40681 gagtatacca aggtcctata gctaactttt ttctttgaac taaatctctt attctatatt
    40741 catcctgagg tctccatttt aaataatcat ctaagagaga agcttgtgca tccatagtaa
    40801 agtatttaaa gtcttctttt tcttctaata tgtctaatat atcttgaaaa tctttcatta
    40861 gatatatttt tgaccttgat gttgtaaaat accattctct atcccaatga ctatgtggaa
    40921 ctacatgtac ttttgtcttc ttcataaaat cctccctaaa tttaattgag aattgagagt
    40981 acgctcaatt ctcaactagc taaaattaaa tctttaattt acattatatc taactctatt
    41041 tcatcaaatt ctgtattttc cgcagtttca tcttcattaa agtctactaa aattgttgat
    41101 aatattgcta ttactaaagc tccaaatatc gcacctacta agtaagccca tccagaacct
    41161 actgatataa atccatataa tccaccaact ggaggcatta tagcatgtac acctaataaa
    41221 gctgataatc ctacacccaa agcacatcct atcatattga caggaactaa ttttaatgga
    41281 ttttttaaag tgaaaggaat tgcaccttct gttattccaa ttatacccat aactatgttg
    41341 ccttttcctg tttcagataa tgtcttagag aatcttgatt ttctaatgaa tgtagctaaa
    41401 ccatatccta gtggagggat aactattgcg cagtttacca atattgctgg tagatagatg
    41461 ccctctaaca ataatgcatt tcctgccatc caagctgctt tatttaccgg tcctcctaaa
    41521 tcaaatccta tcattgaacc taaaattaaa gccaatacca ccgaatttgt tccattttga
    41581 cacatttcag ctacccaagc atttaatgaa gtatttatgt ttcctaaagg ccctgctaat
    41641 acaacactca ttaaaaaccc cgttaatcca actgttataa gtggcattat tataagtggc
    41701 atcattcctg ctgccgaccc agatatttta atttttttct ttaaaaattt gcaaatatat
    41761 ccagcaaaaa aacctgctgt tactgctcct aagaatcctg cattagtatt acttgctatg
    41821 agtccaccaa taaaacctgc acccatagat ggtttttcac ctattgaaaa tgctataaat
    41881 cctgctaata cagtatttaa tagacctatg ccagtccaac caacttgttc cattaagtaa
    41941 agaatatgat aaaaaccgga tacatttttg taagcatcta aacttgttat acccattgct
    42001 aaagctgtaa gttttggtat agctacaact agagatgagc ctattacaag tggcaacata
    42061 tatgaaatac ctgtcattaa gtgtccttta agttcactta aaagagagtt atttttttta
    42121 ctcattttta atcctcctat ataagtttgt tatatttttt gataatatgt tataattaca
    42181 ttagataatt ttttaatttt tgatttttct cattctagat tagagtgaga ttctttttat
    42241 taagaaatag tttctataca ctttgttaag acagcttctg gtttttttaa tgctacacct
    42301 attttaactt ttattacttt tttaccatca aatctttcca ttccagatat agtttggtca
    42361 gatgctataa gtataaagtc tgcatcttgt gcttcttctt ttgttatagt atttactcgt
    42421 cccatagcac cttgttgttc tactttgatt ttatgcccca tttttgatgc agcttgttcc
    42481 aaagcttttg ctgccatagg tgtgtgtgcc aatcctgcta tacatgatgt tattgctact
    42541 attttcataa ttattcctcc ttcattttat tagttatata ttttactaaa tgacttgcat
    42601 cactagcatt tttaacttca cttataaaat catcttccat taagcatgtg gctaatttag
    42661 atagagtttt caaatgtata tttccttcat tttcatgtgg agctaacaaa ctaaatacat
    42721 atctaacctt actatcatct aaagttttcc actctaactc gttagttgtt ttaatataga
    42781 gtatagaagc ttcttttaca tttgcacttt ttgtatgagg tatcgcaaat ccatctctta
    42841 ttcctgttgg aaattcgctt tctcttttta gaaggtcttt taaaagagca tctttattag
    42901 ttgtaatacc tagtatataa gcactgtctg caataaaatt taatacttcc tctttgcttt
    42961 ttaagtcttt atctataaat atattctttt cttgtagtac catatatttt ttccactcca
    43021 ttcgtaatgt cttaacttat atttatattg taatcgttat cctaattaaa ttaaatataa
    43081 ctaatttcca cttcgacatg gaaatttata ttatgataat aactaatttc catgtcgaag
    43141 tggaaataaa ttatgataat acaattttat tagagtaatt gtattatatg agtgtaaata
    43201 gtataattta gaagaaattc tataaggggg gatatttatg cacaagagat tgctcacgtt
    43261 atttaaacta ttaaatgaaa gtgatgataa aattacttgt aaaactttaa gtaatcattt
    43321 aaaagtgagt gagagaacta taagaaatga tattacttct ataaatgaaa ctttagagaa
    43381 aaatggtgct attattaaaa taaaaaaagg agaaggatat tatatagata ttcttaattt
    43441 agcattatac caacattatc tagcattaat atctgatgat attatggatt caagtgaaat
    43501 accagattct cctatagaaa gaaatcaata tattttaaaa tatattcttt ataacaatac
    43561 atatataaaa ctagaagatt tagctaatag cttgtatgtg agtaaattta caatactaaa
    43621 tgatataaaa agaataaagc ctattttgtc aaagtataat ttaatattag tttctaagcc
    43681 atattatgga gttaaggttg aagggaagga aatagatatt cgaagatgta tttctaataa
    43741 tatgataaat aggaattttg aaaattatat aattggaatt acagatagag aaatagaatt
    43801 atttaataat gtagatttaa tagagcttca gaagatagtg ctaagtgaaa ttaataaatt
    43861 taatatcaat ttcttagatt ttaatctaaa aaattttatt attcatttat ctattactat
    43921 aagcagaata ctaggtggtt actgcttaga taatgtttta gatgtggttt taacagattt
    43981 tcaatcgaat acggctgttg aaaatatatt taattatatt gagagtaaat atactataat
    44041 tatttcaaag gcagacagag tttatttata taatcatttt ataactaaaa gttctctttt
    44101 ggataacgtt tccaataggg cagataccaa aattatagag tatgttgagg aaattttaga
    44161 agtaatcaac aatcaatata cttttgacct tagaaatgat agtgtattat ttgatgattt
    44221 agtactgcac tttaaatcaa ttcttaattc taaatcttat aatttaaata aggtgaatcc
    44281 ccttataaat acaataaaaa gtaattatcc tttagcattt gaaataagtt taaatgctat
    44341 agaaaaagtt tttaaaaata gtatttactc tttaacagaa gatgaaattg gatatgtatc
    44401 cctacatata ggtgctggaa tagagagatt ttttcaaaac aatattaagt gtaaaaacgt
    44461 agtattagta tgtggttcag ggtatggttc aagtaggtta ttagaggttc aattaaacaa
    44521 agtttttcat gataaaataa atatacttca atgtctatca tttaatcaat ttttagctag
    44581 tgaattgtca gatgtagata taataatatc gacaattcct ttaaatcatg atagtattcc
    44641 tattgtatta gtagatttaa aactattaaa aaaagatata gagaatatat ctaagtcaat
    44701 cactaataat tctcgtattt atagtaatct tttggacaat ttctttgata aaaatttatt
    44761 tattgttaat cctaaaatca aagagaagga tgagcttata aagttgatgt gcaacaaatt
    44821 aactcaaagt gaaattgtaa ttccatcatt tactgaatct gtattctaca gagaaagttt
    44881 atcttctacc aatatagatg attttttagc tatacctcat cctatggaat taagctctat
    44941 aaaaactaag atttgtattt ccatattgaa tgaaccaata tattggagtg aagattctac
    45001 tgttaaatta atcatgatgt tggctataaa taaagatgat tatataaaaa taaactccat
    45061 ttatgatatc cttttaaaga taattcatga caatgatatt agagatagta tatctaattg
    45121 taatgatttt gatagttttc tttccataat caagtctata atataaaatt ttatattaca
    45181 taagttttat aaaaaataaa tagaacaatt ttttgttgat aatataaata gtaatgagta
    45241 atttttatat tattttctat tactttatac tgattgtaat tagatacaat agagggtctg
    45301 tctcaaaata gagataatcc tttttttatt gttgaaatga taaaaacata tttgatttca
    45361 tataaaaaag agtgtctcat gaactaaaaa gttcattttg agacatcctc tttattattt
    45421 tatattaatt atctcttgta tatactacta tagcatccct cagaaactta gttagtccag
    45481 gctgttcttt atcataataa gatgtaaagc gttcgtcaca tacatacatc tgtgctaaag
    45541 aggcatgagc ttccttagaa tatgtgctcc aagtgtagct caaccattta tgatgtaatc
    45601 ttgcaacttc ttgagcaagt tcactggagg catcaccagt tttaaaagct tttttaagct
    45661 tactaattat ttcaatgctt agattttgcc aatcttcata atcttgttta gacatatttt
    45721 taaatttttt atttgaggca actataatat ctttaccata attctctcta atttcagttc
    45781 cataattttt ttcattttca tcaatcatct tttctttaaa accttcaaat ttttctatat
    45841 ctgtcatagt gtattttccc tccttcagag ctatagtttt agttacattt tctattagta
    45901 aatcaatttg ctttcttttg actagtaatt tattatggtg tttttttaac gcacttaaac
    45961 tatcgaagtt tggtgaattt ataatgtttt ttatattttc taagttaatt cctaattctc
    46021 tataaaaaag tatttgttga agtttattaa cttcattttg accatatata cgataacctg
    46081 aagaatttat tttaagtggc ttaagaagac ctatttcatc ataatatcta agtgtcctag
    46141 tacttatacc agctagttta cttaattttt gaactgtata ttccataatt agtacctcct
    46201 ataaactaaa tatacacttt tacgcaacgt aaatgtcaat atattaaaat ataaaaattt
    46261 atatctttta ataaaaatat aaaaaaatat ctttactgga tattttacac acaagtgtca
    46321 atactcacta gtgaaaatta aaaaataaaa tttatagact atttttatta aaatatagaa
    46381 ggtctatagt ttaggaggaa ctgtatgaat ttaaaaagaa gcaatgaaaa acgagaagag
    46441 tatagaagaa tgtattcaga taaagaaagt tttttaagtt tgattcaaaa ttttacaagt
    46501 gtctcaatcg caaaggaatt aactcttaaa aatatagaat tagaaacatc ttttatatgt
    46561 gaatataaag gaaaagaagt tgatgtaatt tataaagtgt tttctaaaaa tggtaaagta
    46621 tcacattata tagtattaga gtttcaaaca gaaatggata ctgaaattgt accaagatta
    46681 aaatcgtata gagaacagat ttggaagagt tttattatga aaaaaagtct tgaagaaata
    46741 gaagataaaa attttaagct tcctaaagtt ataccagtcg ttttatatag tggacctgaa
    46801 aggttaagca gaaaaaaagg aattttggat attgtagaat ctatatcgga gttcagtaat
    46861 aattctagta tgaaaaatta aaactacata atatgtttat tggtctaaaa tggaaaactg
    46921 tcgcataaac ttgaatatga aaatatttat agatacaggt tctatgtgga ggtgttccat
    46981 gagaaataac aagtctaagg tattgctagg aatactttgt ctggcaacag gaatggctgt
    47041 aattctttca atgttgcttc ctggctggat ttggtcagca cttaccgcat taatacttat
    47101 tggatgtgga gcattattat ttttttgtta aaatagtttt aactataaag tgtggggtga
    47161 gtattgatga aagtagtaac aataaaatta ccaaaatgga tttcaagtat aatcctaaaa
    47221 tttatgagaa agagtaaaaa tgattaaatt aaaaagccta cttacggaag taggctttta
    47281 aacgtggtta ctaagctctt tcaattttac cagaacgtaa acatctagta caaactttta
    47341 ctctcttagg agctccatct ataatcgctc ttacgcttct taagttagct gaccatgttc
    47401 ttttattatg tttatttgag tgtgatactt ggtttccaga aaccttacct ttaccacata
    47461 cgctacatac ttttgccatc tacgcacacc tccttaaaat gataactatt taaagactaa
    47521 aaacatattt atattatcat aaataacaaa aatttgcaat agaaatatat atttgcctta
    47581 cacatattga agaatttctt attatcatat aaaattatat atataatttt atataaagta
    47641 aatatatttg gaaaataatt attatttttc tttgaatata tatactatag aagaaatttt
    47701 atccaaaaac ttttctaggt ttaaattata ccatatttat agtatgatat gattataatt
    47761 ttatataata aataagtaag aatagtaaaa aataaattaa gaaatgtttt taataaaaat
    47821 aagcttaagg gggtcaacca tgagtgcaaa ggtaacgaat caatatggaa gtatagaaat
    47881 agataatcaa gtaatagctc aagtcgtata tagagctgca atggaaagct atggcttagt
    47941 aggtttagca tataagtcta aaggaatagt agagctatta aaaggtgaga acgcaactaa
    48001 aggtgtaaga gttgaggaag tagaagaaga tgccatagca atagaacttt atgttataat
    48061 acaatatggt acaaatatat ctactgttgc caataatata atagatagag taaaatatgt
    48121 agttgaaaaa atgactggcg taagagttac tagaattgat attaatgtac aaggaataag
    48181 agttaagtaa tttcatagga ggaaacaaat gattcagtat atagatggta aaaggttaag
    48241 ggagatgttt atttcaggtg caaacaatct ccaaaacaat aaagatttag ttgacaagtt
    48301 aaatgtattc cctgtaccag atggagatac aggaactaat atgtcattaa caatatctta
    48361 tgccttaaaa gaattagcaa aagttgaaac tgataatata tcagacatcg gaaaagcatt
    48421 atctaaaggc tctttaatgg gagctagagg aaactcagga gttatacttt cacaaataat
    48481 cagaggtata gctaaatcta tagaaggaaa aagtaaatta tcaacagaag atttagcaaa
    48541 agcttttaaa aatggttcag acacagcata taaagctgtg ataaaaccaa ttgaaggaac
    48601 tatacttact gtggttagag aaagtggaga ttttgcaata aaaactgcaa aaaaagaaaa
    48661 agatgtagta aagtttttaa gtatgcttgt gaaggagtcc aattcttcat tagagagaac
    48721 tccagacctt ctaaagaatc taaaagaggc tggtgtagtt gactctggtg gaaagggtct
    48781 tgtacttata tatgaaggaa tgttagcttc tataaaaggc aataatatag aaataaaaaa
    48841 cgctgaccta gatactaata tttcaacaag tatggatttt gcaaagagta ctattagtac
    48901 agatgatata aaatattgtt attgtacaga atttattcta gaaagttcta aggtagaaga
    48961 tactaaaata agagacataa tgatggctta tggtgatagc ctagcagtag ttggagatga
    49021 tggagtcata aaggtacatg tacacactaa tgacccagga aatgtacttc aagaagctct
    49081 aaagtatggt caattattaa ctataaaaat agaaaatatg aagttacaac atgaaaatac
    49141 attactagat gtagaagaaa agaaagaaaa tgatagtgaa cctttagaag aagaaaaaga
    49201 gtttggattt atagctactt ctatgggtga aggtttggca aatatattta aagattttgg
    49261 agttgaccat ataatagaag gtggtcaaac tatgaatcca agtactgaag attttatgaa
    49321 tgctataaag gatataaatg ctaaaaatat atttattttc ccaaataaca gtaatataat
    49381 aatggctgct aatcaagcaa aagaattgag tgataaaaat ataatagtta tacctacgaa
    49441 aaacacacct caagggtttg ctgcactagt aacatttaat ggagaattaa gtgaagatga
    49501 aaataaagaa gctatgatga atgccttaag ctcagttaaa tcaggtcaag taacttttgc
    49561 tgttagggat acagtgatga acgaaattga tgttaaagaa ggtaatataa ttggaattgc
    49621 agaaggaaat ttattatcag caggagatta tgtggatgaa gtaacatcaa accttattga
    49681 aaagttggtt gatgaagata ctgctataat aacattattc tttggtgaag atgttacaga
    49741 atctcaagca aatgaactac gtacttcttt agaagaaaaa tttgaagatg tagatgtaga
    49801 gttatattat ggaggacaac ctctttatta ttacttaatt tcagttgaat aatgattata
    49861 agaacctgta tgaccaagta gcttttataa aattggttgt acaggatttt tgtgtagtag
    49921 gtgatatatt tgttggattt atataaagat gttcaatatg ttaagggaat aggacctaaa
    49981 aaagcagata agttaaataa gctgggtata tttacactaa aagacctatt gtattatttt
    50041 ccaagacaat ttgaagatag aaataatcta aagaaaatag cacaattaga agatagtgag
    50101 aaagttacaa taaaagcagt aatatcaagt ataaatacat ttagcccaaa agaagggatg
    50161 actttaacaa aaattgatgt aaaagatgag acaggttcgg ctaaattagt attttttaat
    50221 aagagttata taaaaaatac ttttcgtcca ggagattcaa tattagtttt tgggaaggtt
    50281 aagaaaaagt ttaataactt agaacttaca tcatgtgaat tagaatatct tactaattca
    50341 cctaagaata catgtagatt tatgcctgtg taccagctta catatggtgt tacaaataaa
    50401 gaaattatga gtataattag aacagtactt gaagataaag acttaattat acaagaatat
    50461 atgccacaga gaattataga taaatataga ttatgtagta tagattttgc agttagaaac
    50521 atacattcac caaatagtaa ggaatcatta aaaatagctt tatatagaat tgtatttgaa
    50581 gaattactta tactacaact agggttgttc gtatttaaaa gtggaagaaa caaagaagat
    50641 ggaataaaat ttgaaacaag taaagattta aaaaaaataa taaatgcttt accatttaaa
    50701 ctgactaaag ctcaaaacag agcattaggt gaaattatac aagatatgga ctcagagaaa
    50761 ataatgaata gattggttca aggtgatgta ggaagtggta agacagtagt agctctctta
    50821 gcacttgcaa attgcgtttt aaatggttac caaggtgctt tgatggctcc tacagagata
    50881 ttagcagggc aacattatat ttcacttact gagtctctaa aagattttgg aataaatgta
    50941 ggtctattaa taggtagtct tacaaaaaaa caaaaggata cagtattgga acaagtaaag
    51001 aataatgaga ttgatatatt aataggtaca catgcactaa ttgaagacaa ggttgaattt
    51061 aataatattg gtttagttat aacagatgaa cagcatagat ttggtgttat gcaaaggagc
    51121 aaactttcat tgaaaggtgt aaatcctgat atactagtaa tgacagcaac accaatacca
    51181 agaactttag cacttatact ttatggagac ttagatattt ctattataga tgaacttcct
    51241 ccaggaagac agccaataga aacacttgct attgaaaaaa gtaagagaga tagagcatat
    51301 aacaaccttg taagaagaga ggttgaatca gggagacagg tgtatattgt atgtcctctg
    51361 gtagaagaaa gtgaagccat agaagccaaa tcagcagttg aacttgttga ggagttaaga
    51421 gcggaatatt ttcacgactt aaggcttggg ttgcttcatg gcaaaatgaa gtcaagtgaa
    51481 aaagatgaag taatgggact ttttaaaaat aaagaaatag atattttagt ttcaacaaca
    51541 gtaatagaag ttggtgtcaa tgtgccaaat gcaacattaa tgataataga aaatgcagaa
    51601 agatttggac ttgcacaatt acaccagctt agagggagag ttggaagagg aagtcataaa
    51661 tcgtactgtg tactaattta tgattctaaa acagatgtat gtagacaaag aatggctata
    51721 atggaagaga ccaatgatgg ttttaagatt tcagagaagg atttagaaat aagagggcct
    51781 ggggaatttt ttgggacaag gcaacatggt cttccagaac ttaaggtagc aaacttattt
    51841 aaacatataa aaatactgaa gttagcacag caagaagctc gatatatatt gggtgaagat
    51901 aataatctac aattgaaaga aaacatggca ctcaaaaaag aaattataga taaatttaaa
    51961 gatacactga aagaaatttc attaaattaa ttttaaatta tgttaaaata ttactaatgt
    52021 aataatgtgc tgaagggaga ttgtcatatt gagagtaatt tcaggaaaag cgagaggatt
    52081 aaaactaaat actccaaaaa atgaagatgt aaggccaact acagatagag taaaagagtc
    52141 tctatttaat atgataaatt catatataat ggaaagtgaa gttctagatt tatttgctgg
    52201 gactggctct ttaggaatag agtgcttatc tagaggtgcc aaggcatgta cttttgtgga
    52261 tatcagtaag gaaagcatag atattgttaa gtccaatata aaaaaggcaa gagttgaaag
    52321 cgaaagtatt attttaaacc ttgattttaa aactgcaata gataaactta aattacaaaa
    52381 tagtaaattt gacataattt ttatggaccc tccgtattat aaaaatatgt ttatagaagc
    52441 tattgaaaaa attgataatt ccaacctatt gaacgaagat ggaataatag ttgtagaaca
    52501 tgatacgaat gatttatttc cagataagat atgtaaatta gagaaaacta gagataagaa
    52561 atatggaaat actacattaa ctttttataa gatggaggca taatatggaa aataaaccta
    52621 gaaaagctat atttgcagga agttttgacc caattactaa tggacattta gatattattt
    52681 gcagggcttc aaagttattt gacgaattac aaataggagt attaaataat cctaataaaa
    52741 agggtctatt tagctttgat gaaagagtaa aacttataga aaaaagtaca agccatttaa
    52801 ataatataaa agttgtgact tttgatggtt tattaataaa ttactgtcaa gaaaatggaa
    52861 ttggagcact agttagaggc gtgagaagtg gtgctgatgt tgattatgaa cttcagatgg
    52921 cgcatatgaa tagagagctt aatccagata tagagactat aattttacca agttgtacaa
    52981 aatattcatt tataagttca tctttaataa aagaggtttt gctctttgat gctgatataa
    53041 aaaatttggt tccaaagatt gttttggaag agttaaagaa aaaaactagt gggggtaatt
    53101 gatatatgaa gatagattta gaaatgattg aactatttga gcagttagag gagatattta
    53161 gaagtgcttc tacaattcct ttctcacata aatgcacagt ggataaagac gaagttttag
    53221 caataattaa tgatataaga actttaatac cagaagaagt aacacaggca gtatggatta
    53281 ataaagaaag aaataaaata ataagtcaag ctaagcaaga tgctacaaat atagttgaac
    53341 aagctaaaaa agaagctgag agaatacaac aagaatatca agacaacata gaggaattaa
    53401 agaaaaattc tgaagatgta gtaaaggcat atgtagaatc cagtgaacct gttgttcaag
    53461 cagaccaaag agctaaagat atagttgata gagctgagag aatagccaat gaaataagaa
    53521 ttgggtcaat tgaatatgca gaagatgtgc tttctagtgt tgagtataat ttaaaagaaa
    53581 tattagaaga agtaaaaaga gataaagctg aacttagacc taaaaaataa attttaaata
    53641 aataaaaatg gagctatcac acaaaaaatt ctaattgatg tgtgatagct ctcttttaat
    53701 acaacaattt tttgttatct aattgtactt ttcatatcac ttatatttca ttttgatatt
    53761 ataatgcaat ttaatctttt atttgtttaa atcagatgct gtattaatag gattcttaat
    53821 tgctatgtta acatctacag ctttttatta ttgtatatta aaaagatgag taattagttt
    53881 ttaaatgggt gaaaatagat tggcaaatat caattgtaaa tattagaaac gttgtcatag
    53941 aaaaaaacta tattaaaaaa aagtacatag aaaaaactga ttagacaata aatacatgct
    54001 ttgataatat tttaaatgga ataaaaatgt gtagaattat aatgaaaaag aaaataaaat
    54061 ggagggagta aaagtgggta tgttaaaaaa gttatgttca ctagctatgg tggcaattat
    54121 gactacaaca cttataacag ggtgtacaag tggaaatgga aaagattcaa aaaaggatgg
    54181 cgaaaaagaa aaactagttc tttggatgcc accagtagaa aataatatga aggaagtttg
    54241 ggaccctatt ttagataaat ttgaggaaaa aaataactgt gaagtagatt tacagataat
    54301 tccttgggat aattattctg aaaaatttgc aacagctata agtgctggcg aaggtccaga
    54361 tgtagggtat atgtatgcag aaatgtatcc acagtttata gaaagtggag cagtagaaga
    54421 tttgactaat tatgcaacta aagaagataa agagcaatct atttatataa aaacatctga
    54481 aatgatgggt ggaatgtatg gtatgccatt ccaagcagca aatccagggg tactatacta
    54541 taacaaggat attttagaga aattaggaga aaaacctcct aaaacatggg aagattttaa
    54601 aagaatttgt aaaaaagcaa cacaagatac tgatggtgat ggaaagatag accaatgggg
    54661 attagctcag ggatggggag ctaaaacttt tggtaactta aattggaact ggtatcctta
    54721 tttatggcaa gctggtggag atatatttaa taatgattta aaatcagtta aatttaatga
    54781 taagagtggt ttagaagcag ctaatttctt aaaagaatta caagcatatg tgcctgaaga
    54841 ttctttatct aaagatagta atgaaatgat agaaagtgta tttggcccag gaaaagcagc
    54901 atttacaata atgttatctt ctgctgcaac aagtgtattt gatgaatcat tcccagactt
    54961 aaattgggga tttgtaactg gactagaaga taagaaagca gcaacttttg gagcagtaga
    55021 ccatttatct ttgatgtcat ctgcgaaaaa taaagaactt gcgtacaagt taatacaaca
    55081 tatgttaagt gttgaatcaa tgacagaatt tcataaagca ataccaagag caccaataac
    55141 aaaaggtgaa ccatatcaag gtgatgaaag attcaaagaa atggtggaaa atgacaagga
    55201 tgtatacaga ccattagtag taggacctca tggagttgaa atatatgaat atttatggaa
    55261 agaacttcaa actatgattt caggagataa aactccaaaa caagcattag atgatgctgc
    55321 aaaatattca aatgatttat tagcacaata aaagtttaaa gctgtaatat gttgtaaagt
    55381 actttacaga ttaaaattag cattgtattt ataaatacaa tgctaatatt tatattggag
    55441 aggataaaat ggaaaactta gttagagagt ttgaagaaaa ttcaaaaaga aaaaaaacaa
    55501 aattaaatat taaaccatat atgtatatat tgccactggg aataatttta gtgacgtttt
    55561 atgtgatacc aataataatg tcaatatact ttagttttac aaagtataat attattagtc
    55621 cagctacttt tataggttta gaaaattata aaaaattatt tacagatgaa acattaaaag
    55681 tatctattat aaatactatt aaatttacta ttgttgtagt accttgccaa actatattat
    55741 cattgatttt ggcagtttgg attacaggaa agggaaatag taaaatagct tcatttgcta
    55801 aaggtgctat atttatacca gtattatcat ctatggtttt gataggtatg gtatggagag
    55861 ctttattgaa tggagaaggt tctattatat atcaggtatt aggtgctttt ggaatagagt
    55921 catctaaact tttaggagat agtaagacag cattacctac acttatgttt atatctatgt
    55981 ggaaaaatat agggtatttc atggtgattt atatttcagc tataatgaat ttaccaaaac
    56041 actgctatga agtagctaag gttgatgggg ctacaaaact tcaagaattt ataaaaataa
    56101 ctgtaccttt attgaaacca actacaataa tggttgtatt tttaggggcg atatggtcac
    56161 tacaagtatt tgatttagtt tatactgtga caggtggagg cccaggtata tctactatga
    56221 gtatagttat gcatgcattt aacttaaact ttaaaaactt taattctgga tatgcaatga
    56281 ctgtagcaaa cgtattattt ttattaatag cagtagtttc tattttacaa aataaacttg
    56341 taaaacgaga caattcagat ttttagaaag gtaggtataa tatgaaaaca acaagaagaa
    56401 tattgagtga tggtttactt ttatttatag cgtgtgcaag tttggtacct tttatataca
    56461 tgttgataat atcattgaag ataacatata actcatatag tttggatata tctttctcaa
    56521 cagtaaccct tcaaaactat atagatatct ttactaaaaa agggtttgca caatattttt
    56581 taaatacagc aatagtatct ttttcaggtg tattattaaa tttagtattt agtacattag
    56641 caggatattc ttttgcgaag atggatttta aaggcagtga taagttattt ttatttatga
    56701 taatgacttt aattatacct tctcaagtta caatgatacc actatatata ataatgaaac
    56761 atttaggatg gataaatagt tatcttgcac ttattatgcc aataccaact gcatttggtg
    56821 tatttataat gagacaagct attttaggag tgccaaaaga gttattagaa tcagcaaaga
    56881 tagatggttg ctcggacttt agaattttaa tacagatagt tttaccacta atcaaaccag
    56941 cattaattac actagcaata tttactttta tgggagcgtg gaatgagttt atgtggcctc
    57001 ttatagcgac aactaaggat gcaatgagaa cattaacagt tggattatct actcttaaga
    57061 cattccagat aactaattat ggacagatga tggcaggtgc tacaataaca tttttacctc
    57121 catttatttt ctatttgatt ttgcagagta aatttgttga aggtgtgtct ttatctggca
    57181 taaaaggtta aatagtataa tttaataata taaaataaac ttatataaat atggaggaat
    57241 ttaaactatg gaaatttcat atgtactgaa agattgcaca tttaaacata ataaatactc
    57301 agttatagaa actgaaactt gggaagataa ggatttggat attgtagtag ctaaaggtga
    57361 aaaatttgca tttcaaatta tgctaaaagc aacagaagaa tttaattgta caattgatta
    57421 aaaaatagct acgcacactc gtgactttag tcatgagtta gtagctaaat tagtcagcat
    57481 atagggaaac ctatatgtag agataggata gaacctatcc aatactactt gaattgctgg
    57541 aaacccctaa agctaaccaa actaaaacat aaggatgaaa taaacctaag tgtgaaagtt
    57601 gcgaaagtag aaaaaattgg ttagatggta taaggttaaa ccctaagtac tttaaaatgg
    57661 gcaatcagca ggtaaactcc gaataggaga aacttcaacg actattcctc ttgagggaag
    57721 tacactacaa gctattggta gtggaagtgg
//
LOCUS       DBGJFK010000017        57448 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.017, whole genome shotgun sequence.
ACCESSION   DBGJFK010000017 DBGJFK010000000
VERSION     DBGJFK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57448
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.017"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(25..429)
                     /locus_tag="ACOIAP_001274"
     CDS             complement(25..429)
                     /locus_tag="ACOIAP_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HGZ2638177.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNYVKPWKDAEIYIDKYMVK
                     QDISKDNVKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLKSNEELKSVKYPPIYLKYKPDK"
     gene            complement(621..1808)
                     /locus_tag="ACOIAP_001275"
     CDS             complement(621..1808)
                     /locus_tag="ACOIAP_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide family glycosyltransferase"
                     /protein_id="HGZ2638178.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVHRGNEVLYYSFNEFRDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPRLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQSFIEIIRIIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIESLGSIPNNF
                     KVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVANRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(1840..2055)
                     /locus_tag="ACOIAP_001276"
     CDS             complement(1840..2055)
                     /locus_tag="ACOIAP_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006774905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HGZ2638179.1"
                     /translation="MVPPKGKFFFGAVVVGERGQIVIPKEAREVFNINAGDKLLVLGD
                     EERGLGIVHQRDLINFIGHVGVVPKEE"
     gene            complement(2083..2274)
                     /locus_tag="ACOIAP_001277"
                     /pseudo
     CDS             complement(2083..2274)
                     /locus_tag="ACOIAP_001277"
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(2703..4652)
                     /locus_tag="ACOIAP_001278"
     CDS             complement(2703..4652)
                     /locus_tag="ACOIAP_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGZ2638180.1"
                     /translation="MKRKYPNLCKPIKIGNVTFKNRMFSAPMGGTDITADCTIGSKST
                     AFYELRAKGGAGAVTISECMVHPETDGSHAYHLDLKIVDSLASFTYTADAIRRHGAIP
                     SVELSHSGQYSGTYLVDKDKKRGLSQWGVSPSVRPDGLEIKELTEEIIAEIVESYGNV
                     AALAKRAGFEMIMVHGGHGWLINQFLSPYFNKRNDKYGGSLENRVRFAKEVLDSVRKA
                     VGPGFPIEFRMSGSELFEGGYDLDYGVEIAKLLESRVDLLHVSAGTYQRGFAVTHPSM
                     FLEHGCNVYLAEEIKKHVNIPVATIGALNDPEMMEEIIASGKADVIYMARALLADHEL
                     PRKVMSNQDEKIVKCLRCFTCMAERATTSTRRCTVNPLIGRELDGTEVIPVLKPKKVL
                     IAGGGPGGLQTAITAAKRGHKVILCEKTNELGGILKGEQALPFKYEMYELGNTFGKIA
                     EDLGVEVRLNTRVTKEYVENENVDALIIAVGSEPLVPSIEGLDGENVVIVNDYYLEKE
                     KVTDEVVVLGGGLAGCEAAIHLAQEGKTVHLVEMRAELAPDANIRNRPILLQEIEKQG
                     IYVYTEHKGLSVTTEGVVCMNKSGNKINIPGTSVICALGQKPRREVVDALLDCAPYVA
                     QIGDCVRASTITNAVYQGHHVALDI"
     gene            complement(4624..5922)
                     /locus_tag="ACOIAP_001279"
     CDS             complement(4624..5922)
                     /locus_tag="ACOIAP_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGZ2638181.1"
                     /translation="MNLTQKRWIILIASCFINLCIGSIYAWSVFASPMAEHLNSIAGT
                     TFTAASLAIVFTVTNSVGPITMITGGMINDKFGPKKVVFVGGLVFGIGMILAGFSKGL
                     PMLILSYGIITGLGVGMVYGCTISNSIKFFPDKSGLVGGITTAAYGFSSVIMPPVANW
                     IINKYGVTSAFKSIGLVFLIIVCVSSFFIKKCPADFTPEGWIPPEKKGKVRVIINKNW
                     KEMLSTPIFYLMIIILTCGAFYGLMCVSLASSLATNMIGMTSSDAAIVVSILALFNTL
                     GRIVAGYISDKIGRINTLAGALVISIFGLLCLLFSREGDVATFYIGIIIIGICFGSFM
                     GIFPGFTVDKFGPKNNSVNYGIMFIGFAFAGYVGPAVMKNVYATDGNYQRAFIIAIVI
                     ALIGFILTFLYKYINKIQNLKIENLMKGDIKDEKKISKSM"
     gene            6173..6730
                     /locus_tag="ACOIAP_001280"
     CDS             6173..6730
                     /locus_tag="ACOIAP_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGZ2638182.1"
                     /translation="MRTLKYAILGLLNRNPMTGYDIVKEFNFQLAEFWNAKHSQIYPE
                     LKKLVNEKLIVYDIKISGDVLEKKLYTITEKGKDEFLKWLEKDEPMERTPKDIFRLRM
                     YFSNNLDIDTRLILLEHQLLQHQERIAFLYSQMERYSEVPPLNSNDFGDYIVLDGAII
                     REQGAIKWLTNCINHHKNLDNTTLK"
     gene            7154..7903
                     /locus_tag="ACOIAP_001281"
     CDS             7154..7903
                     /locus_tag="ACOIAP_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HGZ2638183.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKKTKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGAIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(8063..8404)
                     /locus_tag="ACOIAP_001282"
     CDS             complement(8063..8404)
                     /locus_tag="ACOIAP_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HGZ2638184.1"
                     /translation="MQEITSKFKECRKAISAMGDETRQLILITLLESDFNGIRVGEIT
                     EKTHLSRPAVSHHLKILKEAEIVNVRREGTKNYYYLDSKKSQWKSLTELINLIFVGIQ
                     HISENDIRKGD"
     gene            complement(8444..9226)
                     /locus_tag="ACOIAP_001283"
     CDS             complement(8444..9226)
                     /locus_tag="ACOIAP_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2638185.1"
                     /translation="MNMKYQHIIKVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQD
                     CLMCGHCAAICPQKAITLTGFDEPPIELTNKPNLDSDELLMAIKSRRSIRKFKDKEVS
                     LEIVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSK
                     EVEIDDKFFFKNAPIAIMIITKDKISGSLAASNMSLMAESYGLGVLFSGYFSDVANNS
                     PKLKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEAANVRYL"
     gene            complement(9639..11066)
                     /locus_tag="ACOIAP_001284"
     CDS             complement(9639..11066)
                     /locus_tag="ACOIAP_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGZ2638186.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDKHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPRGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEIDSNNLVGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGIAPEMESGDIELLNKYTVDFISFSYYNSRCVRTDENAGDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVYIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRTKKKSFEWYKKVIASNGEDLY"
     gene            complement(11127..13055)
                     /locus_tag="ACOIAP_001285"
     CDS             complement(11127..13055)
                     /locus_tag="ACOIAP_001285"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGZ2638187.1"
                     /translation="MGKYKQLAQEIVKNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDNSSANSETKKSGSILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKFIPDLVKFFFVPMLTLLITVPVALIV
                     LGPIATFGSTVISQVVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVASPIKGEVLKLS
                     EIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDAGVEVLIHIG
                     LNTIQLEGRCFEACIKQGDRITKGQTILNFDIDAIKELGYSVVTPIVITNSSQFLDVV
                     ETGRKNIELEDNLITVLF"
     gene            complement(13200..14042)
                     /gene="licT"
                     /locus_tag="ACOIAP_001286"
     CDS             complement(13200..14042)
                     /gene="licT"
                     /locus_tag="ACOIAP_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGZ2638188.1"
                     /translation="MIINKILNNNVVITLDDNDEEIIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEVSNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGVKLPEDEAGFIAFHI
                     VNAQLSEGHTFASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLN
                     NAHEGGTDKELLSIIKSKYNKEFECVVKIKDFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNI"
     gene            complement(14205..14360)
                     /locus_tag="ACOIAP_001287"
     CDS             complement(14205..14360)
                     /locus_tag="ACOIAP_001287"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638189.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFIWK"
     gene            complement(14460..14909)
                     /locus_tag="ACOIAP_001288"
     CDS             complement(14460..14909)
                     /locus_tag="ACOIAP_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2638190.1"
                     /translation="MEIREILSEESIILDLKSTTKEGIIQELVDKLYDTGSIDLKSKF
                     IKALKRREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGIDWPSIDGLPVKVIIM
                     FAMPQSGDNEDMTLISKIAYILGGKDISERLLNANTKKEILDIFYEV"
     gene            complement(14899..16806)
                     /locus_tag="ACOIAP_001289"
     CDS             complement(14899..16806)
                     /locus_tag="ACOIAP_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2638191.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKIIE
                     KYLETFNIKIDIKRGYGILIESLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISKLTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTISQPYYINLITHILICLKRIEEGNQIESQEEREVSVDNLDELVYQNVTALIGKIEN
                     RYGVKITKDEIMYIYIFLVSSGFSSESNNSYNDESYRLSESEKFSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSNRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDISNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVMQMESLIGVDLGSKYKSISLGKDLNIYIHNQSKLN
                     KGIMNVNNINRTIDIYLETSNQSFLKNILMEISNLYRQKSYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(17073..18968)
                     /locus_tag="ACOIAP_001290"
     CDS             complement(17073..18968)
                     /locus_tag="ACOIAP_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGZ2638192.1"
                     /translation="MIGQILRSDCIVLDKQLQTKKDVIDYMANHLYHGNYINDKEKFI
                     VDINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDKEITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMDENLLKHLLSAETPYEILSIFNNKAVESGDSSDNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQMSRFIGKKVLQKKVADAKNVSLAKNLIINAENGMAKEIKPGGRTLEDSK
                     EILQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFSTG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSSPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVEVLGA"
     gene            complement(19004..19882)
                     /locus_tag="ACOIAP_001291"
     CDS             complement(19004..19882)
                     /locus_tag="ACOIAP_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGZ2638193.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREVVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FIEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCREVLEKNSSLYEPDTIYPPCIDAAREVIEFKMN
                     LFNTIDKLKCFYKNKN"
     gene            complement(20434..22128)
                     /locus_tag="ACOIAP_001292"
     CDS             complement(20434..22128)
                     /locus_tag="ACOIAP_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638194.1"
                     /translation="MIKKIKRSKFTPKNVISIILYSILFWILIGYIIIPIGNTFTQAF
                     QGKGGYSFEVFKEYFSNTNNLKVVSNTIILGFGSVLVCGIMGISLALYMTFVCDKHKK
                     IIHILLLSPMMIPGVIMVIACIQLYGESGIVTKSIEILLSFIKKPYDFSGLKGVLFVV
                     AYTQYVYFYLNVYVALKYVDYSTVEAAKGMGASKIRVFFDVIWPVITPAIITSTIITF
                     ASGISSFSAPNLIGGGFKVLSTQIVRSKANNHMDIASVQVIILLLMGISFMILLQYYG
                     KKYGVVASLKSQGYKVHNRKKDLFTFVCKVIIEIQIVMIMLPIVTIVYLSFVSTHSIM
                     TTIFPRDFTLENYQMIFQKSRVLQPILNSLKMSLMAVVIGLIITIPVSYLVIKKDTTY
                     NRLAKFIIMLPWSMPASAIAVNLINTFNQKSIFAFNESLIGGFYIVPIAYTIYALPLL
                     FSSNEVAMKSINLGLEESSRSLGAGRIKTFYNVIVPNMMPGIISGAILVFIRTIGEYT
                     MSALLYGVYNRPISISIVTNMQEFKIGVSMAYGVLVIGICYIALGIIFKLDRKRFT"
     gene            complement(22130..22567)
                     /locus_tag="ACOIAP_001293"
     CDS             complement(22130..22567)
                     /locus_tag="ACOIAP_001293"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638195.1"
                     /translation="MPKGAPLWKPPQEKAVRYPSTGRIPPFVVSSPFHGLFSPFVKFG
                     VANFVGTSNCIEKEDYVNFNIEKETKPYIYKRPEEMVLLQNTNQSGFIKVKVESKNFL
                     GAILEYTVSNNGKKYQVTELNRLNNSNKLNVGDMAYLGVLQGN"
     gene            complement(23013..23747)
                     /locus_tag="ACOIAP_001294"
                     /pseudo
     CDS             complement(23013..23747)
                     /locus_tag="ACOIAP_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            complement(23829..24323)
                     /gene="lnu(C)"
                     /locus_tag="ACOIAP_001295"
     CDS             complement(23829..24323)
                     /gene="lnu(C)"
                     /locus_tag="ACOIAP_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(C)"
                     /protein_id="HGZ2638196.1"
                     /translation="MVNITDVKQILQFAIDAEIKVFLDGGWGVDALLGYQSRAHNDID
                     IFVEKNDYQNFIEIMKANGFYEIKMEYTTLNHTVWEDLKNRIIDLHCFEYTDEGEILY
                     DGDCFPVETFSGKGRIEEIEVSCIEPYSQVMFHLGYEFDENDAHDVKLLCETLHIEIP
                     NEYR"
     gene            complement(24347..25384)
                     /locus_tag="ACOIAP_001296"
     CDS             complement(24347..25384)
                     /locus_tag="ACOIAP_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595-like element ISSag10 family transposase"
                     /protein_id="HGZ2638197.1"
                     /translation="MPTIKDALDIIGKLTVAEQESLKTMLLSPAFVKSLNIEDFVAKE
                     RFANGRVCPLCGCIHVVRNGHRKDGTQRYVCKDCGKSFVIATNSIVSGTRKDLSVWEQ
                     YIDCMMNGLSIRKTAVACGIHRNTAFLWRHKILDALQNMADDVTLDGIIEADETFFAI
                     SYKGNHSKSKTFAMPRKAHKRGHSTHIRGLSQEKVCVPCAVNRNGLSISKITNTGRVS
                     TRDLHHIYDGRIKTNSTLVTDKMNSYVRFTNANGIDLVQLKTGKAKKGIYNIQHINSY
                     HSQLKRFMRGFNGVSTKYLNNYLVWNNLVNYAKESDMEKRNIFLTFVLATLKTAKCRD
                     LSNRPAVPLVA"
     gene            complement(25463..25612)
                     /locus_tag="ACOIAP_001297"
                     /pseudo
     CDS             complement(25463..25612)
                     /locus_tag="ACOIAP_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            complement(25762..26538)
                     /gene="ant(9)"
                     /locus_tag="ACOIAP_001298"
     CDS             complement(25762..26538)
                     /gene="ant(9)"
                     /locus_tag="ACOIAP_001298"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)"
                     /protein_id="HGZ2638198.1"
                     /translation="MNINEFPQQVNQVISIAETILQGQILGIYLYGSATMNGLRPDSD
                     IDILIITKQELSNSIRADLTKQLLKISGSVGCIEKRPLEVTIINQSDIVPLQFPPKCQ
                     YMYGEWLRGEMEAGEYPQACNDPDIMILLWQARKNSITLKGAESKELIPAIPFHEIKK
                     AIRFSLPGLISSFKGDERNVLLTLSRMWFTLVTEEITTKDVAAKWVILKLPERFSPLL
                     TTAKEAYLGNLSDEWETVEKEAMALVEYMKKQIEELLRTE"
     gene            complement(26563..27333)
                     /locus_tag="ACOIAP_001299"
     CDS             complement(26563..27333)
                     /locus_tag="ACOIAP_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGZ2638199.1"
                     /translation="MPLVKHDYPVLEYDTASKAVFQPGNGKKCFPAKAVFAFLGDEVE
                     NYAHTHDGIQIDEFESATRRYPIYECLYNQEKICLCPAPVGSAAAVQVLEYLIAGGVT
                     KIISVGSCGVLEDIPENRFLIPVSALRDEGTSYHYLPPSREVEISKAGINAIESALSQ
                     KNIPYWEVKTWTTDGFYRETVEMVQYRKEEGCQVVEMECSALAACAKFRKVTWAMLLF
                     SADTLADPHKYQEREWGKTSISIALELALDAVLSVVEE"
     gene            complement(27358..28155)
                     /locus_tag="ACOIAP_001300"
     CDS             complement(27358..28155)
                     /locus_tag="ACOIAP_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2638200.1"
                     /translation="MALPGTPGQRISDLCNGNHITQKELAEKIGVSASQLSRIVSGET
                     RTVSSDILIGVAKEFKVSTDYILGLSTVSVRKSYDISELGLSEGAVRGLVTGAVDVQI
                     LNRLLEHRNFPKLIDLIRIYFQDTAAKGITARNQLIEMATASLSDLMKEHPEHRAEAK
                     QDLQLLNAQKMGEHEAEIEKIKNVFLAILRDIKKDIDNGEQPGEAVTAAMFQAMRDAL
                     AEQKQKPLSIDDVAAMVAGQIGQLTPMDEETADLFKQLAKKMMKGIE"
     gene            28626..29039
                     /locus_tag="ACOIAP_001301"
     CDS             28626..29039
                     /locus_tag="ACOIAP_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP protein"
                     /protein_id="HGZ2638201.1"
                     /translation="MRDNPYKDLPPLERRPDGSLYRMTPAQKKQAASLIRRECCCCEN
                     GNCIVLDDGDTCTCPQTISFSVCCKWFRWAVLPLDGTLEAGIFRDKDLKRCAVCGGVF
                     VPRSNRGKYCPDCAARVHRRQKTESERKRRSAVDS"
     gene            29151..29546
                     /locus_tag="ACOIAP_001302"
     CDS             29151..29546
                     /locus_tag="ACOIAP_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGZ2638202.1"
                     /translation="MTNTIYIHQPEKAFSFTRLPNFLFEAPTFKPLSNEAKVLYAFIL
                     RRTELSRKNGWADDCGRIYLYYPICEVVDLLHCGRQKAVNTLRELQYAGLVEIQKQGC
                     GKPNRIFPKSYEAVPNTDFKKSGSGTPEG"
     gene            29730..30674
                     /gene="mobV"
                     /locus_tag="ACOIAP_001303"
     CDS             29730..30674
                     /gene="mobV"
                     /locus_tag="ACOIAP_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HGZ2638203.1"
                     /translation="MAQHAILRFEKHKGNPARPLEAHHERQKEQYASNPDIDTSRSKY
                     NFHIVKPEGRYYHFIQNRIEQAGCRTRKDSTRFVDTLVTASPEFFKGKSPKEIQAFFQ
                     RAADFLIGRVGRENIVSAVVHMDEKTPHLHLTFVPLTKDNRLCAKEIIGNRANLTKWQ
                     DDFHAYMVEKYPDLERGESASKTGRKHIPTRLFKQAVSLSRQARAIEATLDGINPLNA
                     GKKKEEALSMLKKWFPQMENFSGQLKKYKVTINDLLAENEKLEARARASESGKIKDRM
                     ERAKLESELHDMQRLVDRIPPDILAELKRQQRQHGKER"
     gene            30658..30873
                     /locus_tag="ACOIAP_001304"
     CDS             30658..30873
                     /locus_tag="ACOIAP_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007215986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638204.1"
                     /translation="MERKGDFISTSIRYKKETEVVTFQGREITLENLSPVFTPEQEAA
                     KRRELEQQLYEVFRKYADKRQKEEAGA"
     gene            30965..32461
                     /locus_tag="ACOIAP_001305"
     CDS             30965..32461
                     /locus_tag="ACOIAP_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2638205.1"
                     /translation="MNNRIDAIYARQSVDKKDSISIESQIEFCKYELKGGNCKEYTDK
                     GYSGKNTDRPKFQELVRDIKRGLIAKVIVYKLDRISRSILDFANMMELFQQYDVEFVS
                     STEKFDTSTPMGRAMLNICIVFAQLERETIQKRVADSYYSRSLKGFRMGGKAPYGFHT
                     EPIKIDGINTKKLVANPEEAEQVKLMFEMYAEPGTSYGDIVRHFAEHGIKDFSRPALA
                     SLLCNPIYVKADLDIYEFFKSQGTVIINDAADFTGTNGCYFYRGRGMKGDTKHNLQGH
                     TLVMAPSEGLVSSELWLKCRKKILANASYQAGRKAVNTWLAGKIKCGRCQKALKAEGS
                     YGRWYFRCSKRSDNKSCEGAGTLRIPDTEAIIYAAMVKKLKPFQTIKGRKNAMKSNPK
                     LTALQVELAQVQHEIETLIDTLTGANPILLSYVNSKIEELDGRKQELVKKIAELSVDT
                     ISPEQVKEISGYLDTWEEVDFDDKRRVVDLMISAIYATSESINIVWKI"
     gene            complement(32509..33204)
                     /locus_tag="ACOIAP_001306"
     CDS             complement(32509..33204)
                     /locus_tag="ACOIAP_001306"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638206.1"
                     /translation="MKNIELKEINHYYGKEKVLYDINISIKEGEFFTLLGPSGCGKTT
                     ILRIIGGFIKPSSGSIYVGDKNITNLEPENRNMGTVFQNYALFPNMTVEENVSYGLKI
                     KKLSKKIIKEKCDNYLELAGMKDFRKKKIDELSGGQQQRVAVARSLATEPTMLLLDEP
                     MSNLDIALRIKMREEIREIQQKIGITTLFITHDQQEALAISDRIAVMDKGKVLQIGVP
                     MEVYKKPLNDFVA"
     gene            complement(33223..34080)
                     /locus_tag="ACOIAP_001307"
     CDS             complement(33223..34080)
                     /locus_tag="ACOIAP_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638207.1"
                     /translation="MGLKISDYKLLCNKGNGDFNEDIVGLSPYGAWVLDGATGLNNKN
                     LVSTESDAKWYVSWWNSYLHENMEREDSLKVIIKEGIEEITKEYYKLTYDKEVEAIDI
                     PSCSCSILKFYKDKIEYLLLGDCTLLVNHNESVKILKDETLCRLDKKIFDFMQEAKDV
                     TNLTLKERKAEVMPIIIENRLKKNTVGGYWALEFSKEAVDNCISGFIDIEYKMKIMMA
                     SDGFSCGYDRYKIFDKNEMMKIAEIKGIDYIYRKVRELEKDDEMAIEFPRFKIYDDSS
                     CVYLEIYKY"
     gene            complement(34358..35401)
                     /locus_tag="ACOIAP_001308"
     CDS             complement(34358..35401)
                     /locus_tag="ACOIAP_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGZ2638208.1"
                     /translation="MKRKIAVVLLTVAMLLSLVACSNDNTSKSDKLEDTLVVYTTHGE
                     DMLGAISEEFTKETGVNVEFINLKGELADRVRSEKDNPQADIMFGGDTSTYMQLKEEG
                     LYEKTKPSWNNELDKSYKDSDGYWYGTIKTPVMIFYNTKLLSADKVPKDWSDLTKEEY
                     KDLIVTRDSLSSSMRSTISNLINYYSNTKSEEEAWKYLEDLNKNIKNYYNSGSVMYSA
                     IGKGEAAISVAVLSDIIENKEKNNMPLEVVDAESGSVVITDCVAALKNAPHPNAAAKF
                     VDFVGSAKVQAMVANDFNRIPTLDSALKDSPKWMSKEYKAMDVDWSVIGKNQSNWIEK
                     WETDIIDNNKTIK"
     gene            complement(36367..37800)
                     /locus_tag="ACOIAP_001309"
     CDS             complement(36367..37800)
                     /locus_tag="ACOIAP_001309"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGZ2638209.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KVTDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPNGDESIPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     SRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAIPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITDEDKKILKEGTVDFIGCSYYLTTVVSADKTMKTTGNDSAGKA
                     DVVENPYLKTSDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     GYRIEYLASHIREMKKAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
     gene            complement(37823..39664)
                     /locus_tag="ACOIAP_001310"
     CDS             complement(37823..39664)
                     /locus_tag="ACOIAP_001310"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGZ2638210.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETITKKAVLQVQNTGEQGEKVSIVSRIFE
                     SISGAFSPLIPALAGAGMIKALLTILTIMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLGANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDVISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     DGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYITHMNAGDKVKKGDKIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            complement(39790..40623)
                     /locus_tag="ACOIAP_001311"
     CDS             complement(39790..40623)
                     /locus_tag="ACOIAP_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGZ2638211.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGRDELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYKFSKKAVEYLRKKLDKDIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENANVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            complement(41661..41873)
                     /locus_tag="ACOIAP_001312"
     CDS             complement(41661..41873)
                     /locus_tag="ACOIAP_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638212.1"
                     /translation="MAILMKTKIKEYREKFLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEQE"
     gene            complement(41874..42290)
                     /locus_tag="ACOIAP_001313"
     CDS             complement(41874..42290)
                     /locus_tag="ACOIAP_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638213.1"
                     /translation="MSKSETGVKSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNIDTGIILIAVLYIQSLSKLVLYIYFDKRGICN"
     gene            complement(43598..44227)
                     /locus_tag="ACOIAP_001314"
     CDS             complement(43598..44227)
                     /locus_tag="ACOIAP_001314"
                     /EC_number="3.2.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
                     /protein_id="HGZ2638214.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKAKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVVPNYSGEKYYKMESVVSDEHLV
                     TAPGIAPLEFTFQVLKLLEVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(44306..45268)
                     /locus_tag="ACOIAP_001315"
     CDS             complement(44306..45268)
                     /locus_tag="ACOIAP_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638215.1"
                     /translation="MAKIDNMMSILWMLSSDKKITAKEIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDIGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLIALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEIRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQSIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIQPLSLRKKMIEDLLELIDYYQI"
     gene            complement(45746..45967)
                     /locus_tag="ACOIAP_001316"
     CDS             complement(45746..45967)
                     /locus_tag="ACOIAP_001316"
                     /inference="COORDINATES: protein motif:HMM:NF015935.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HGZ2638216.1"
                     /translation="MSKKLFVDSDRERFVVICLDTEWQPVSIEVVSRWAINSVLIYPR
                     DVLTDVSKVITSTIICWVTLILARRWSYN"
     gene            complement(46993..50469)
                     /locus_tag="ACOIAP_001317"
     CDS             complement(46993..50469)
                     /locus_tag="ACOIAP_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638217.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNVSNTFADTIEESTNAGN
                     VEGDTNAGNVEGDTNAGNAEGDTNAGNAEGDTNAGNAEGDTNAGNAEGDTNAGNAEGD
                     TNVGNAEGDTNVGNAEGDTNAGNAEGDTNEGNAEGDTNEVLVEEDTNAEEYDSVGDFK
                     ISGGEINVDFKFESGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFNGVNIK
                     TASNSPFTLTPDKDGGAYAHIILQDGSKNILKSGDQLYPGIRAGKSTTLIIDDSVVNR
                     DIEGEFIVPENGKIPRDVTLENGDKLKKGDRLTLLDSKNRGSLTAVGNSYAAGIGGGD
                     TENGGNIIINGGIINATAMEGYNTGFGAGIGGGSIGDGGDITINGGTVTAKGAYHGAG
                     IGGAYYISGNHTLSPSVVDRNKGGGYSGNITINGGLCYSYGGAHGSAFGDGCVNPGAN
                     RGYRVLVTGGTVLPYMTGAGDWIFDLSAITGDVIVTGGSLKATTFKSSGETVAYGDLE
                     KKTKVFMSKVSLKYLGQDKVNTKLVDDFTMQINGKEYPYGAPSYTDDQGVLYLWFSDK
                     FTGSEVSVKLAIVDKDTGDTLKSDTFYIKDIGPTTPFLKQYEEFIIDEINTPPGSINK
                     RYDGLPFGKEQEKAFLDWILKDGIPVTNPKGGKLTDGTYIIISSQRLNEETMEPDTSL
                     GSDDLTKQVDVGKYQLIITSKQYASVAPFNESYWGHRSHYNYAEITPADTETSLVVET
                     PKVKTDVFKPTDTFTLNATVSPDKKEGPDCASPKGYVQFYINGKEYKDPVELKTHDKV
                     SESHNYSTASIEWKPLDSNHHILNTEQTITVKYIGDDINYTKDSKDEKKLKLDITNVD
                     IDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNRDGIWKP
                     DKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTDSGGYDTGNPDPNKPDPD
                     NPNPDNGGNSKPDSGNGGNSKPDSDNGGNSKPDIDTDGDGKPDIDGDGKPDIDIDTDG
                     DGKPDINIDTDGDGKPDINIDIDGDGKPDINIDIDGDGKPDINIDIDGDGKPDINIDI
                     DGDGKSDVNIDIDGDGKPDINIDTDESLDSNAGQNVQTGDQSNIMLDLALMFTSLFFL
                     IKNLINKYLRRK"
     gene            50739..51152
                     /locus_tag="ACOIAP_001318"
     CDS             50739..51152
                     /locus_tag="ACOIAP_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HGZ2638218.1"
                     /translation="MKKLVKILINIICIITLIFSSLSIYIKLSEYKKADEVYTELREN
                     TSNNNSKHQELYDKNNDYRFWLKINNANIDYPVVQGYNKDFYLTHDFYKNYLPAGSIF
                     MDYRNNFENDKSLIVYGHYMKNKTMFGQLESRNKI"
     gene            51472..52272
                     /locus_tag="ACOIAP_001319"
     CDS             51472..52272
                     /locus_tag="ACOIAP_001319"
                     /inference="COORDINATES: protein motif:HMM:NF026010.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-terminal phage integrase SAM-like
                     domain-containing protein"
                     /protein_id="HGZ2638219.1"
                     /translation="MATKRANGEGSIVKNIRNGVQIGWRASISIGRDEKDKLIRKQFT
                     VKTQKELKEKLDIYRTKMLLGSIVSADKITFEDWFYTWLFDYRAKNLKPKSFERYEGI
                     YRNHKKDTELGKIKLIDLRATHIQRYYNKLIDVYNKPASTIITLNTRLKPCLTETEKQ
                     GYIQKNYCKMITLPSDNKIKEVQILSITDQKKFIDSIDGDKFEILFLLALSAGLRLGE
                     LLGLKWSDISFDDESLTVSMTLQRVTEINKDGTREKKSLNSIQRLKIL"
     gene            52346..52621
                     /locus_tag="ACOIAP_001320"
     CDS             52346..52621
                     /locus_tag="ACOIAP_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2638220.1"
                     /translation="MLGDAYINNNYVICNDTGLALNNNRPGKILDSLLKKLNIPKIKF
                     HALRHTYATRLFEAGVPPKTVQTLMCHYDYGYIHTLCTIPSRMLWIK"
     gene            complement(52773..53372)
                     /locus_tag="ACOIAP_001321"
     CDS             complement(52773..53372)
                     /locus_tag="ACOIAP_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638221.1"
                     /translation="MSQNIDFNKSNFYLRLDERLAVPLKYAYVSTILKFQKWRGCTFD
                     FSNTKLEKLKNIIVHGDNDNYNKLLMVIKKRYDDILDEEFWHIEIKELPYIDRGFKSN
                     KDIITTFIHGKYYPKRKAFRHIDFIKNQYPFKEYCSKQEDNSTNEIKIDFYITKECHY
                     KVWCIENIDIQEHIWCELVNVSLSEEYRKLFGEILDSSK"
     gene            complement(53398..53697)
                     /locus_tag="ACOIAP_001322"
     CDS             complement(53398..53697)
                     /locus_tag="ACOIAP_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638222.1"
                     /translation="MAYSDIYSISCGEKEFPTNITIDEDLLFCVVTCFVLDRFRYDDL
                     NIKSVISYEKHMYDINDYKLTKIENLDFKQNGFIYDKKYYLYNIFIDKSPLNKYK"
     gene            complement(53725..53976)
                     /locus_tag="ACOIAP_001323"
     CDS             complement(53725..53976)
                     /locus_tag="ACOIAP_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGZ2638223.1"
                     /translation="MEKLIQDIKNLDSYYNTSYYTFHLDEPLWKSLKVRNWSGVPYYI
                     KQLCNEVKSLIKERNLTQSEIFQYITDPKKRTHYFFVAQ"
     gene            complement(54191..56122)
                     /locus_tag="ACOIAP_001324"
     CDS             complement(54191..56122)
                     /locus_tag="ACOIAP_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2638224.1"
                     /translation="MFLDRIIMENVGPIDNLDIGFPFNEDGSPKPIIFVGENGKGKST
                     VLSNIVDSLFEFAKQPYNDITETNKDGTTPYFKVLSWKNTKVGCDYSFSFINFVNGEQ
                     NFQYIEKLGNLSFEQCIEKTSGLLNLDNNWGNRKNIKDITKNKEYFEEEFANKSFCFF
                     PPNRYETPHWMNQNIISENLITINDKISGKLNKPIIVQNVTETNIKWLLDIIVDSRAD
                     LIQSDLGGWNSEQDLNNIRLLKIARENVEEILSEIVKKDVKFGLNWRNSGGSRFNIID
                     RSTNSMIIPTLDALSTGESALFNMFSTIIRYSDYGDINKSIKLNEIEGIVIIDEIDLH
                     LHSSIQCDVLPKLIKKFPKVQFIITSHSPLFILGMKDIFKEDGFKIYEMPTGENIGPE
                     EFSEFERSYEYYKRTELFSKDIQDILKSKNGKTLIITEGKTDWKHMKAGLLKLKEQGL
                     YHDLDIEFLEYENDIKMGYNNLINICEAASKLRNNNKVICVFDRDLSDRDLRKVKDEN
                     TNYKLWGNNVISMVLPLPDNRVEIDKIMCIEHYYSDEEIKTFYKGRRLFLGDEFNSKL
                     GLHILGDKICQDKNKCGKKSIIDSGCVVCDIKNPEDNIALSKNDFADSILNGVEEFKN
                     ISFENFKLVFDLIQILVNE"
     gene            complement(56197..56546)
                     /gene="ssrA"
                     /locus_tag="ACOIAP_001325"
     tmRNA           complement(56197..56546)
                     /gene="ssrA"
                     /locus_tag="ACOIAP_001325"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(56704..57159)
                     /gene="smpB"
                     /locus_tag="ACOIAP_001326"
     CDS             complement(56704..57159)
                     /gene="smpB"
                     /locus_tag="ACOIAP_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGZ2638225.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
BASE COUNT        18393 a        10698 c         7225 g        21132 t
ORIGIN      
        1 aaaatccttc tattttgtca taaatcattt atctggctta tatttaagat atattggtgg
       61 atactttaca ctttttaatt cctcattact ttttaaaagt ttattattat tttccatatc
      121 ataaatttgt aacattactt tatttacata tagagcataa taattatcac tataaaaata
      181 ttgatactca tatcgagggt catctttgta atacactttg tatagtattc cttcataact
      241 tgccttcttg gctttttctt ttgtaatact ttttacatta tcttttgaaa tatcttgctt
      301 taccatatac ttatcaatat atatttcagc atctttccat ggtttaacat agtttttata
      361 tacaacaaac cctgttacac ttataatacc tataattaat actataaaaa taactttata
      421 ttttttcata ttaatcctcc ttcatttatt gtttaaaact taatataatg cattaaaaaa
      481 aggatgttat cttttttatt aaaatataac atccctcata tttagcatca atatatatgc
      541 cccaactagt aggttaaaag gccccactgt cagtactttg attaaattgc atgtatgtat
      601 atatattttt aaaaaatcta ttatatatca acttgtctac tattacatat aatctgtaat
      661 attacatctg ctgctttttt tgagcctcct gcattataaa agctttttga tagtttagtt
      721 gcattttctt tatattcatt gtcatttata acttgaaata ctgctttttt aatactttct
      781 gacttatcct cttttaacat aattcctgct cccaaatgaa caactctatt agctaccatt
      841 ctctgctccg aatgttgagg aaataatacc atgggtactc cataatataa actttcatta
      901 acactattca tcccagaatg agtaacaaac acatcagttt tttgaagtat agcaatctgt
      961 tcaacactat ttttaacctt aaaattattt ggtatacttc ccaaactttc aatatcagta
     1021 cttctaccaa cagacataat cacatcaaca tcagaatctt taaatgcatt tatacagttt
     1081 ttataaaagc taacattttt attattaatt gtaccaagcg aaatatatat tagctttctt
     1141 tttctctctt taggttcaat aatcaacttt gatactgatg gacctacaaa tgaatactta
     1201 ctagagaagg tttctaccat tggttgaaat tcttttgatg tatatacaat agtatccgta
     1261 tcattatcat tagaaactat agaaataaaa ttttttactt catacccttt tctttgtaaa
     1321 agctttattt ttttattaat acgtcttaca ccaaaaatta tacgtataat ttctataaag
     1381 ctttgtttca tcaactttgc tgtatgttta ttaaatgcaa aagttgttgt agagcataca
     1441 tatggaatat taagtttttg tgcaaataac tttccccaaa aacttaatga atctgataca
     1501 atgcaatctg gattaaaatc tttaagttct ctacaaactt tttcatctaa agaaatagta
     1561 gtatctacta tcatctcaat taatctggga aaatccttac caattttttt ctcatctcca
     1621 ggaagtagtt ctggaaggta tttatcacaa caaataaatt ttgctccagc accttcaatt
     1681 ttatctctaa attcattaaa agaataatac aatacttcat ttcctctatg cactaactca
     1741 cgaactactt caatagtagg attagtatga ccatatgcag gaatgctaaa aaatactatt
     1801 ttactcatat ttcatacctc cttttataat tttttaaaat cattcttctt taggtactac
     1861 tcccacatga cctataaaat ttatcaaatc acgttgatga acaattccta atcctctttc
     1921 ctcatctcca agtaccaata atttatctcc tgcatttata ttaaatactt ctcttgcttc
     1981 ttttggaatg acaatttgac cacgttcacc aactactact gctccaaaga aaaactttcc
     2041 tttaggaggt actataatac ctgttttttc ttccgaatga ttaactaagt catctagttt
     2101 gacattgtac aattttgcaa gtttaatgca actacctata tcaggaatag attctccact
     2161 ttcccatttt gctattgatt gtctagaaac attaagtttt tcagctaatt cttcttgtgt
     2221 atactggtgg atttttctta gactttttaa attctcatta atcatatttt tcatacctcc
     2281 tatgtttata atattggatt tattatttaa attctattaa ctaatcttaa cattcatata
     2341 tatatttata tactttttat tagataaatt tattgtttag gtaacatact tccttaagtt
     2401 ataataaata aaagcaagca caaatctatc aacttttgct aaagtattta agttagagtc
     2461 atttacattg ttaaatactt ctacacctta aaaagtttta ctcatcaatc aaatgaaaac
     2521 ttgcaataag aattaaaatt ataataacaa aggtgctgtc tcaaaataaa gataatcttt
     2581 tttcattatt gaaatgataa aaatatattt gatttcacgc aaaaaagtgt ctcatgaact
     2641 aaaaagttca ttttgagaca ctcctttttt ataataaaac aatactatct acttcttttt
     2701 aactatatat ctagcgcaac atgatgccct tggtatactg catttgttat tgtagatgca
     2761 cgaacacaat ctccaatttg agcaacatat ggagcacaat caagtaaagc gtctaccact
     2821 tctcttcttg gtttttgtcc aagtgcacat attactgaag ttcctggaat atttatttta
     2881 ttcccagatt tattcataca tactacacct tctgttgtta cacttaaacc tttatgctct
     2941 gtatatacat atataccttg tttttctatt tcttgtagta atattggacg attccttata
     3001 tttgcatccg gggcaagttc tgctctcatc tctactaagt gaacagtctt cccttcttga
     3061 gccaagtgaa ttgcagcctc acatcctgct aatcctccac ctaaaactac tacttcatca
     3121 gttacttttt ctttttctaa gtaataatca ttaactatta ctacattttc tccatcaaga
     3181 ccttctattg atggaacaag aggttcagac cctactgcta taattaatgc atcaacattt
     3241 tcattttcaa catattcttt tgtaactctt gtatttaaac gtacttcaac acctaaatct
     3301 tctgctattt ttccaaaagt atttcctaat tcgtacattt catatttaaa tggaagtgct
     3361 tgttctcctt ttaaaattcc acctaattca ttagtctttt cacaaagtat tactttatgc
     3421 ccacgctttg cagctgtaat agctgtttgt aaccctcctg gtccaccacc tgctattaat
     3481 acttttttag gttttaatac tggaataact tcagttccat ctaattcacg tccaataagt
     3541 ggattaacag tacaacgtct tgtagaagtg gtagcacgtt ctgccataca agtgaaacat
     3601 cttagacatt ttactatttt ttcatcttga ttactcataa cttttcttgg taattcgtgg
     3661 tcagctagta atgcacgagc catataaata acatctgctt ttccactagc aattatctct
     3721 tccatcattt ctgggtcatt taatgctcct atagtagcaa ctggaatgtt tacatgtttt
     3781 ttaatttctt ctgcaagata tacattacat ccatgctcta agaacataga aggatgtgtt
     3841 actgcaaatc ctctttgata tgtacctgct gatacatgaa gtaaatctac tcttgattcc
     3901 aataatttag caatttctac tccataatct aaatcgtatc ctccctcaaa taattcagaa
     3961 ccactcattc taaactctat tgggaatcct ggacctactg ctttacgaac actatctaaa
     4021 acttctttag caaaacgaac tctattttct aaagaaccac catatttatc atttcttttg
     4081 ttaaagtaag gtgataagaa ttgattgatt aaccatccat gtccaccatg aaccataatc
     4141 atctcaaacc ctgctctttt agccaatgct gcaacatttc catacgattc tactatttca
     4201 gcaattattt cttctgtaag ctcttttatc tctaatccat caggacgaac actaggactt
     4261 actccccact gtgataatcc tcgcttctta tctttgtcaa ctaaataagt tcctgaatat
     4321 tgtcctgaat gagataactc tacacttggt attgctccat gacgacgaat tgcatctgct
     4381 gtgtaagtaa aacttgctaa agagtcaact atttttaaat ctagatgata tgcatgtgaa
     4441 ccatctgttt ctggatgaac catacattcg ctaattgtaa ctgcacctgc tccacctttt
     4501 gctcttagtt cgtaaaaggc tgttgatttt gagccaattg tacaatctgc tgttatgtct
     4561 gttcctccca taggtgctga aaacattcta tttttgaatg ttacatttcc aattttaatt
     4621 ggcttacata gatttggata ttttcttttc atcttttata tctcccttca ttaaattttc
     4681 tatttttaaa ttttgtattt tatttatata tttatataaa aatgttaata taaaacctat
     4741 taaagctata actatagcta taatgaaagc cctttgataa ttgccatctg tagcatatac
     4801 atttttcata actgcaggtc caacatatcc tgcaaaagca aatccaataa acatgattcc
     4861 ataatttaca ctattatttt taggtccaaa tttatctact gtaaatcctg ggaaaattcc
     4921 cataaatgaa ccaaagcata tacctataat tattattcca atatagaacg ttgctacatc
     4981 tccttctctt gagaataata aacataataa accaaaaatt gaaataacta atgcacctgc
     5041 taaagtattt attctaccaa ttttatctga gatataccct gcaacaatac ggcctaatgt
     5101 attaaatagg gctaaaattg aaactactat tgctgcatct gaacttgtca taccaatcat
     5161 atttgttgct agagaagatg ctaatgacac acacattaat ccatagaaag ctccacaagt
     5221 taatattata atcattagat aaaatatagg tgttgaaagc atttctttcc aattcttatt
     5281 aataataact cttacttttc cttttttttc tggtggtatc catccttctg gtgtgaaatc
     5341 tgctggacat tttttaataa agaaagaaga aacacataca attataagaa atactaaacc
     5401 tattgattta aatgcagagg ttactccata tttattaatt atccaattag caactggagg
     5461 cattattact gaactaaacc cataagctgc tgttgttata ccaccaacta atccactttt
     5521 atctggaaaa aatttaattg aattacttat tgtgcatcca taaaccatgc caaccccaag
     5581 acctgttatt atcccatatg ataaaatcaa cataggtaat ccttttgaaa aacctgccaa
     5641 tatcatacct ataccaaaaa ctaatcctcc tacaaataca acctttttag gaccaaattt
     5701 atcatttatc attccccctg taatcatagt aataggtcca actgagtttg taactgtaaa
     5761 tacaattgct aaactagcag ctgtaaaagt cgttccagca atactattta aatgttctgc
     5821 cataggtgat gcaaatacac tccatgcata tattgagcca atacataaat taatgaaaca
     5881 acttgcaatt aatataatcc atcttttttg tgttaaattc attattctcc tcctctataa
     5941 atttattaaa tggaatttct tagttaagat tatcacaatt ttttctatat gtaaatataa
     6001 acatgtaaat atttacatgt ttatatttac ataatttctt ttttatatat agctttattt
     6061 atttttatta ctcataattt acaagttctt attaaaacat agttatatta attaattcaa
     6121 attaaatata tcgtgttata ataagtatgt aattaaagaa agaggtgtat ttatgcgaac
     6181 tttaaagtat gcaattttag gattattaaa tagaaatcct atgactggtt atgatatcgt
     6241 aaaagagttc aattttcaat tagctgagtt ttggaatgca aagcatagtc aaatatatcc
     6301 tgaactaaaa aagctggtaa atgaaaagct tattgtctat gatattaaaa ttagtggtga
     6361 tgtattagaa aaaaagttat acacaatcac agaaaaaggt aaagatgagt tcttgaaatg
     6421 gcttgaaaag gatgagccaa tggaaagaac tcctaaggat atttttcgtc ttaggatgta
     6481 cttttctaat aatttagata tagatactag gcttatttta ctagagcatc agttgcttca
     6541 acaccaagaa agaattgcgt tcttatacag tcaaatggaa cgttatagtg aagttcctcc
     6601 tcttaatagt aatgattttg gtgattatat agttcttgat ggagctatta tcagagaaca
     6661 aggtgctata aaatggctaa caaattgtat taaccatcat aaaaatttgg ataatactac
     6721 tttgaaataa taacttgttg attttaatag tgaatttaat tatagatatt aaatttataa
     6781 aaaagactgt acacaacttt gtctttgtat acagtcttct atggttgatt attcaaaata
     6841 gctaattata aaagttaagt attttttatt aagctattat tttatcttct tattaccttt
     6901 caaaatctcc tttatattta caatctttca cagtcgaatt gctatctctt ctcataatac
     6961 aaatccagtt gatgtattgt tactaagttt aatggtaatc aaattcttta ccaataagta
     7021 taaaaattac taatgtgtta taattttctt aactactaaa ttttacatgc atttgaatag
     7081 aatatgtcaa taaattacta taataaataa aaaattaaga gttaaaataa aaaatagtta
     7141 gggagatatt attatgattt tatattttag cggtactggt aatagccgat atgtagctcg
     7201 taaaattgca caagaattaa atgatgaact tatatcacta aatcaactta taaaagaaga
     7261 aaaaacagat gaattaatat cagcagataa accattcata ttcgtatgtc ctacttatgc
     7321 atggagattg ccaatagtgg ttacggattt tataaaaaaa acaaaatttc taggaagcaa
     7381 cagagtttac tttgtaatga cttgtggagg agatacagca aaatctataa actatattca
     7441 aaaactatgt aaatataagg aatggcaatt aaaaggtatg gcagaaatta aaatgccaga
     7501 gaattatata gctttatttt ctacaacaga taaagaaaca tcaaaacaaa tgattaaaga
     7561 agcagataaa caaatatata ggattatttc tgatatacgc aatgaaaatg aatttgaaac
     7621 tattactcct agtggcttag gaggtgcaat taaaagtggt ataataaata cagtttttta
     7681 taagacaatt attagtgcca aaggatttca ttatactgac aaatgcattg gctgtggaaa
     7741 atgtgtagag ctatgtcctt taaataatat taatttaaaa aacaaaaagc cagtttggaa
     7801 aaataactgc acccattgta tggcatgtat ttgtggttgc cccactgaag ctattgagta
     7861 taaaaataaa actcaaaata gagaaagata ctatttagaa taatatattc ttaatattta
     7921 aaccattata aaatgaacta tacccattgt tttatacagt tttacatatt ttaactgtct
     7981 catgggtata gttcaaaaga tagtgtctca aagtgaactt tttagttcct aaatcactct
     8041 tttttattaa atcaagtata ctttaatcac cttttcttat atcattttca ctaatatgtt
     8101 gtattccaac aaatataaga tttattagct ctgttagtga cttccattgt gatttttttg
     8161 aatcaagata ataatagttt ttcgttcctt ctctacgcac attaacaatc tctgcttctt
     8221 ttagtatctt aagatgatga gatacggcag gacgagaaag atgtgttttt tctgtgattt
     8281 ctcccactcg tataccatta aaatcactct ctaagagagt aattaaaatc aactgtctag
     8341 tctcatcacc catagcagag atagctttgc gacattcttt aaatttagac gttatttctt
     8401 gcattctttg ttgacattct ttttccataa actccaccct ctcttataag tatctaacat
     8461 ttgctgcttc tttctgtgca gtacgtctgt atttaacatc tgggtatcca attactagtg
     8521 ttgtaagaac atgattactg cgttttagac ctaaaagctt ttttaacttt ggcgaattat
     8581 ttgctacatc tgaaaaatat ccactaaata aaactcctag accataagac tctgccatta
     8641 gtgacatatt tgatgctgca agtgaaccac taatcttatc ttttgtaatt atcattattg
     8701 caataggagc attcttaaag aaaaatttat catcaatctc aacttccttt gaatatttaa
     8761 tagctatatt tgcaataggt tttatttttc taaaaaattt cactgcttcg ttttcataaa
     8821 ttgacttttt attgtctaaa acaatatatg atacatcttg tgaattttta gcactagggg
     8881 tatacctacc tgcctcaata atttgcttta caatttctaa agaaacttct ttgtctttaa
     8941 atttacggat acttcttcta gatttaattg ccattaataa ttcatctgaa tctagatttg
     9001 gcttatttgt aagttctatt ggaggttcat caaatcctgt cagtgtaata gctttttggg
     9061 gacagattgc tgcacaatgc ccacacatta gacaatcttg ttttttaatt actgactttt
     9121 tattttctat aattatattg tttactggac aatcattttt acaaagccca catccaatac
     9181 aaagctcttt gtcaactttt attatatgtt ggtatttcat attcattcat ctacctttcg
     9241 ttcattggtt taaactatta taacacatag atatttttta tattcattgg taaagaattt
     9301 gattaccatt aaatttttaa tctctctatt acacaaattt ttcatagaat tttaaaatat
     9361 catagtttat acataataaa aaagacaagc ttaaaaccta agctcgcctt tctcataatt
     9421 ttaatacaaa gtaaatttca cttacttccc atacttccta acaattttat tctttaaaat
     9481 tttatttgtg aatcatacta tccataaagt acaacctaaa ataatcctgt gttaattttc
     9541 tatagttaaa aaaagttaaa aattatactt aattattaat ttttatactc ttcttattta
     9601 atttaataca agtttcttat ttaatataaa tttcttgtct aatataaatc ttcaccattt
     9661 gaagcaatta ctttcttata ccattcaaag cttttctttt tcgttcttct taaacttcca
     9721 ttaccactat tatctctgtc tacatatata aatccataac gcttttccat ttcacctgta
     9781 ccagcactta ctaaatcaat aggtgcccat gtagtataac ctaataaatc gacaccatct
     9841 atgtaaactg catcatgcat agcttttata tgttctctta gataatcaat tctgtaatca
     9901 tcttctacat aaccattttc gtcagctata tctttagcac ctaatccatt ttctacaata
     9961 aatagtggct tttcatatct gtcatataca tgatttaatg taattcttaa acctagtggg
    10021 tcaattggcc atccccattg actatatgaa agatatggat ttttagcaga tgtaaatatg
    10081 tttccttcag ccatatcacc tgcattttca tcagttctaa cacaacggct attgtaatat
    10141 gaaaatgaaa taaaatctac tgtatattta tttaataatt caatatcacc agattccatt
    10201 tctggtgcaa tacctttttg ctccatatac tttaatgcat agttagggta tttaccttta
    10261 gattgtacat ccacaaagaa gtaattttct ctatctaact ttgtagcttc ccatacatca
    10321 ttaggattgc aactataagg atatacactt ccagctgcaa acatacatcc aactaagtta
    10381 tttgaatcaa tttcatgtgc tattttagtt gcaattgcac tagctacaag ttcatgatga
    10441 gcagcttgat attttatctt ttcaacatct tcaccttctt caaagcaaat accagcaccc
    10501 ataaatggag catgtaaaat catatttatt tcattaaaag ttagccagta cttcactaat
    10561 cctttatatc ttctaaagat aacattgcat aatttctcat agaaacctat cattttacga
    10621 ttacgccatg caccatactt tttaactaaa tgcattggac aatcaaagtg tgtaatagtg
    10681 actaatggct ctattttata ttttttacat tccttaaata tattttcata aaattgaagt
    10741 cccttttcat ttggtgtttc ttcatcacct cttggaaata ttctactcca tgcaatgctc
    10801 attctatata ctttaaatcc catttcagca aataacttta tatcttcttt ataattatgg
    10861 tacatatcaa taccagtttt agctggataa taatgcttat catcaaaatc gaacattttt
    10921 agttttcctg taataactgc tgttctatct tttcctgttg ggcatacatc tacatttgcc
    10981 aatcctcttt cgtcttcatt atatccacct tcacattgat tggctgcagt agctcctccc
    11041 cataaaaaat cattcttaaa actcatagtc aaagcctcct aaaattataa ccaattcact
    11101 agcttatact aatgccttaa tttttactaa aataagaccg taattagatt atcctctaat
    11161 tcaatatttt ttcttcctgt ttctactaca tctaaaaatt gtgatgaatt tgtaataaca
    11221 attggagtta caacactata tcctaactct tttattgcat caatgtcaaa atttaatata
    11281 gtttgacctt ttgtaattct atcaccttgt tttatacatg cctcaaaaca tcttccctct
    11341 aactgaatag tatttaatcc aatatgaata agcacttcaa cacctgcatc tgaaagaatc
    11401 cctatagcat gtagactagg aaataaggtt gtaactactc catctactgg agcaactact
    11461 tttccatcac taggtattat tgctacccct tgacctagta caccagatgc aaatgctgca
    11521 tcctctatct cacttaattt taatacttca ccttttatag ggcttgctac tatttctctt
    11581 tctaatttag tagacttgac ttcttttatt tcttctttcc ccttatttct tactttttta
    11641 gactcttcta ctttctcatc tttatataaa atcatagtta atacaaaagc tacgaccatt
    11701 gatatagcta taccagaaag agctactatt aagttaccca ttcctccatc tggttcaatc
    11761 attgctggaa gttcaaatat tcccatacct ccagttataa actttctaag attaaagaat
    11821 ccataaaaag ctcctccaat accactagca atacaactta ttataaatgg tttctttaaa
    11881 ggtaataata ttccataaat tgctggctct gtaactccaa atataccaga tataaagttt
    11941 ggtattgcca tctcttttag ttttttatct ttagtcttaa agaatattgc caacacaact
    12001 gctgaacttg caaatgtaca agcaaagaat ggcatcataa cattatcata tcctaaagtc
    12061 ataacattgt ttatatatac aggaataaat ccccagtgca taccaaaaat aacaagaatt
    12121 tgccacgtaa atcctactat agcacctgct aatagtggac taaaatctct gattgaaatt
    12181 acaacttgtg aaataactgt agaaccaaat gttgctatag gacccagaac gataagtgca
    12241 acaggcactg ttattaataa tgtaagcatt ggcacaaaga aaaacttaac taaatctgga
    12301 ataaacttat taaataattt ttcacaccta gatgcaaaat acactataaa tataattggt
    12361 acaactgttc cagtataatc aattgataca attggtagac caaagaaatc aatatatact
    12421 ggtgatgcaa acattgttcc tttaaataaa gtgtacatca catctgctcc tgctgatata
    12481 ctgctacctt gtatagcagg ataacatact gcagctccta gtgctaatcc caacattggt
    12541 tttaatccaa acttcttagc tgaagtatat cctaaaaaca aaggaaggaa tgtaaataat
    12601 gcatctcctg ctgcatttat taccatataa ccaccagata catcactata taaccccatt
    12661 gctacaaata atgcattaaa tcctttcaac ataccacaag ctgccattat tcctaatact
    12721 ggctgaaaaa ttcctgatat tatatctata cccttatcga gtatactacc tgatttttta
    12781 gtttctgaat ttgcacttga gttatctaaa ccaattattt caactacatc tttatagaca
    12841 gcctcaacat gatttcctat aactacttga tattgtcctc cacttttcat tacagtaaca
    12901 ataccttcca tattttttaa tacattgtca tttgctatac tttcatcttt taaagtaaaa
    12961 cgtaatcttg taatgcagtg tactaatcca ctaatatttt cttttccacc aacatttttt
    13021 actatctctt gtgctaattg tttgtatttt cccatttttc tcctccatat ttcgtttaaa
    13081 ttaatttttg aaatttgaag gtttggccaa ctcaatgtta ccatccaacc ataggtataa
    13141 ttttgttaat atcactcctt tcaataacat ttactatata ctactgaaaa ttaatttact
    13201 tatatatttg aatctttaac tacttttgct aaatgtattg ttaaatatat aagctcatca
    13261 tctgttaata tgtagttata ttgtttttta ataaaatcct taatcttaac tacacattca
    13321 aactctttat tatatttaga tttaataata cttaataatt ctttatctgt cccaccttca
    13381 tgtgcattat ttaaaagtaa tctctgtgca aaaaatttca aatgcattat aaatctataa
    13441 taaaacactg attcttcatg aaattctatc ctaaaatgat acctaactat actaagtact
    13501 tcttgtatta actttgtaat atcagatgca aaagtatgcc cctcacttag ctgagcattc
    13561 actatatgaa aagctataaa tccagcctca tcttcaggta attttacgcc tgttttattt
    13621 tcaataatat ctagtgcctt cattccaatt tcaaactctt ctttataaaa tcttttaatt
    13681 tcccaaagga ttgcattttt tacatttatt ccttctttca ttctttgaat tgcagaatat
    13741 gtatggtcac ttaaggatat gtaaatgctt tcatttagct tcttgtttaa ctttatttgt
    13801 gcatactcta taatttcact tgataatttc atgtgctcta taggaatatt attgagtaat
    13861 tcttgtagtt tgtttgatac ttctttattt gatattctaa atactttgtt tactttagtt
    13921 ttatctatta gattgccttt tgatttttga taaccaattc ctttacccat gacgataatt
    13981 tcttcatcat tatcatctaa tgtgattaca acattattgt ttaatatctt attaattatc
    14041 atgattatcc tccttttaag cataaaaaaa acttatccat aataatgggc atactccttc
    14101 ctaggatact gctattatta atgaataagc ttagcttgta cttaaacaat tactacctaa
    14161 ttccaattac tatgataaaa catcatacat attttgtcaa ctttttattt ccatataaat
    14221 agatttacta caccttctgt tataagtaat atttctattt ctttatgcca gtgtggtgtt
    14281 gttaatactt ctccttcatt tgatagacta cgaaaaggaa attcatgtat taatttaggc
    14341 atttctaaat atattgccat atatatcctc tcctttctag tgtctaaaaa ttaatatata
    14401 ctatttaaaa taatacatac tttattttaa aaacctcaaa attataattt atacaatacc
    14461 tacacttcat aaaatatatc taatatttct ttttttgtat ttgcatttaa aagtctttca
    14521 cttatatctt tacctcctaa aatatacgct attttagata ttaatgtcat atcttcattg
    14581 tctccagatt gtggcatagc aaacataatt attaccttta caggtaagcc atctatactt
    14641 ggccaatcta tacctttttt agatttacct attaccacag atgccttctt tacatatttt
    14701 gtttttccat gtggcatggc catttgataa cctatactag tagagcctat tttttctcta
    14761 cgttttagtg cctttataaa cttacttttt aaatctatac ttcctgtatc gtataattta
    14821 tctaccaact cttgtatgat accttctttt gtagttgatt tcaaatctaa aataatactt
    14881 tcttcgctta atatttctct aatttccatt tgttttctcc agtagattat ttttaaataa
    14941 tattttaata tcctctttgc tcttgcaatc tattatatag tttatataac tcttttgcct
    15001 atataaattt gatatttcca ttaaaatatt ctttaaaaaa ctttgattac tagtttctaa
    15061 ataaatatca attgttctat taatattatt gacattcatt atccctttat ttagtttact
    15121 ttgattatgt atatatatat ttaaatcctt tcctaatgaa atagatttat atttactccc
    15181 taaatccacg cctattaaac tttccatctg cattacatca aaattaaaat atatattatc
    15241 ttctaaatac attcctaata agtttgtatc taagttcata cttttcttag gtttagaaag
    15301 taaggcattt tttatattac taatatcact ttccattaat agtactgata caactatatg
    15361 taatttatct ttcaagtcta ggtttacagt agatattaca aagtctacat catctaaatt
    15421 tcgattgctc aactgatgca taggaactat atcaactata gtccattcag gaaattctct
    15481 ttttaatctg gctgcaagta gctgagatgt tccataacct gtatgacaaa ctactattac
    15541 tcttttacta ctcatatttc tctctattgc tgcttgaaaa tatgtggcaa gatacgaaac
    15601 ttcatctata ctaatgttct tcagattatc atactctgtc ataatattta tagtcatcat
    15661 acataatccc aacacatctg aaaatcgctc ttgtatctct cctaataatg gattttttat
    15721 ttggatatca tatcttaatc tgtttaacat aggtcttaca tgagatgcta gacttttttg
    15781 tagtaagtca tcatttttga gatttatatt taaaaattgc gacatattct ctatcattat
    15841 agatgaaaac ttttcacttt cacttaatct atatgattca tcattgtaac tattattact
    15901 ttcgctacta aatccagatg acactaaaaa aatatatatg tacataattt catctttcgt
    15961 tatttttact ccgtatctat tttctatttt gcctataagt gcagtgacat tttgatatac
    16021 taattcatcc aaattatcta cagaaacttc tctttcttcc tgagactcta tttgattacc
    16081 ttcttcgatt ctctttaaac atataagtat atgggtaatt aaatttatat agtagggctg
    16141 acttatagtg tatcctaaat tgtattctaa ctctgtaatt atagtttcta caaatataat
    16201 agaatcaata tcaaataaat ttatcaacgc actaaatgta gcagaatcta atcttgttaa
    16261 cttagatata tcatgctgtt cataattttc atctaataaa tcatccatca ttttggcaat
    16321 cgatttcctt atatccactt ctttacctat aatcttagtt ccctctaaag ttttattaag
    16381 tttcaaattg tattctttta tccatgcctc tatatattta aaatcattta ctatagaagt
    16441 tttactcaca taatatttat ctgctaactg atttattgaa gttatattat ttgaatttag
    16501 taataaatac tttaaaatct ccattcttct ctgttctact gataaagatt tattttcctt
    16561 cgattgtata tttaaactat taattaagtc tatattcttc tttgccaaag attctattaa
    16621 tattccatat cctcttttta tatcaatttt tatattaaaa gtttctaagt atttctcaat
    16681 aatcttcaaa tctttttgta aagttttatc ggatacattt aatttatctt taaagtattt
    16741 tataggtcta tatttatttt cgtttaatat caatttaaga aattcaattt gcctcgacac
    16801 aagcatactt atccctccct acctatgttt atatatttct atgttcatat taagtactat
    16861 tttaacatat ttactaacta tgtaaaatta ctaagatact tctgtatcat aaaagaattt
    16921 atgatacacc ttattaaatt gatataatag aaatataatt tcaaaataaa aaataaggat
    16981 atttagaagt agttaactaa ttctaaatat ccttattttt attctatgta cttgtggtta
    17041 ttctattact tatttttact atcatttata atttaagccc caagtacttc aacttcacta
    17101 ttttcactcc ttatagtagg ctttgttacc cctataatca atgctgttat tactgttcca
    17161 atcaatatac aagctatata tgcaactggt gaactacatg caaatggtat tacaaatatt
    17221 cccccatgtg gtgccattaa agttatatct aaactcatac atattgcccc acctatacaa
    17281 gaaccaatta tatttgctgg aatcattctt aatgggtctg cagctgcaaa cggtattgct
    17341 ccttctgtta tgaaagatgc tcccattata gcagttggta gagatgactt tctttcttct
    17401 ttagtaaact tatttttgaa tatcaacata gctaatgata tcgctaatgg aggtaccatt
    17461 cctcctacca ttaaagctgc tgatggttca aatatattac ttgaaaacat agccaatcca
    17521 aaagctgaag ccgttttgtt aataggccct cccatatctg atgccatcat tcctgctaat
    17581 attgcaccta ataatacttt attagttcca gacatgcttt gtaaccaaga ttgtaaagct
    17641 tcatttaacc atgatgctgg tgtattaact acaaagaaca ttatagctcc acttgtaaat
    17701 gcaatcaaca gtggacatat caatacagca tttactcctt ttaatacatc tggtaaattt
    17761 tctgttatct tcattactcc caaggctata tatcctgttg aaaaacctgc caccatacca
    17821 cctataaacc ctgaacctcc aataactgcc ataaaaccag ctatcatagc aggagcaaaa
    17881 ccttgtcttc ctgctattga tttagctata aaaccagcaa gtataggtat aaataactta
    17941 aatgctgaat ctcctccaag ttgtccaaag aatccagcta tagggttgta tgtttcatga
    18001 gttgggtctg atgcaaatat cccaaacata aatgctatgg ctataccaat tccacctatt
    18061 actacaaatg gaatcatttc ggatacacca ctcattaagt gcttataaac accttttttc
    18121 tctgaccctt ggagtatttc ttttgaatct tctaaagttc ttccacctgg tttaatttct
    18181 ttagccattc cattttcagc atttataatt aaatttttag ctaatgaaac attcttagca
    18241 tctgctactt tcttttgtaa cactttcttt cctataaatc tactcatttg aacttcttta
    18301 tcacaagcta ttattacgta ttcagctctt tttatatctt ctttagtcaa cttattttct
    18361 acacctatcg ctccatgagt ttctatctta acttcatatc caagttcttg ccccgcttcc
    18421 tctaatgctt tttttgccat aaaagtgtga gctatccctg ttgggcatcc tgttattcca
    18481 actataagac ctttattttg attatcactt gaatctcctg attctacagc tttattatta
    18541 aatatactta atatttcata tggagtttct gcacttagta ggtgcttaag aagattttca
    18601 tccattagat atgtagctag tttagatata atcttaagat gttcatctga gcctgactct
    18661 ggaactgcta tcataaaaaa tgacctaagt ttttgaccat cattatccgt aatttcctta
    18721 tcagttctta aatacatcat tacaggttga tttactacat ttgacttagc atgaggtata
    18781 gctattaaat tacccatatt agttgatgat tctttttcac gtttattaat atcaactata
    18841 aacttttctt tatcatttat ataattccca tggtacaaat gatttgccat ataatcaatc
    18901 acatcttttt ttgtttgtaa ttgtttatct agtacaatac aatcgcttcg tagtatttga
    18961 cctatcataa attctcccct cctttttatt tgttacctta taattaattc ttgtttttat
    19021 aaaagcactt taatttatct atggtattga atagattcat tttaaactct ataacttctc
    19081 ttgcagcatc tatacatggt ggatatatag tgtctggctc atataagctt gaattttttt
    19141 ctaatacttc tctgcacttc ttataatatg ccgacttaac atcacttgaa atatttattt
    19201 tacaaactcc tagtttaact gcttgtgcta tttcttcatc tggatttgat gaaccaccat
    19261 ggagaactaa aggtatatct actacttctc ttatttcttt taataaatct agtttaagct
    19321 ctggtttaaa accttttgga tatataccat gtgctgtacc aattgcaata gctagtgtgt
    19381 ctactcctgt tttttcaata aaatctttag ctaattttga atctgtatat attatttcat
    19441 cagtaccacc ttcacttgat gttcctgttg ttcctattgt tccaagctct ccttctacag
    19501 atacatttaa tccttttgct atttctacta cttccctaga tatagctaca ttctcttcat
    19561 atggtaaatg tgagccatca atcattactg atgtaaatcc acatcttatt gctcttaata
    19621 tttgttcttt attttcccca tgatctaagt gtattaccat aggtactttg ctcttatttg
    19681 cttcttctat acaactagct acaaagctat cccctaggaa gcttagctca tttgggtgta
    19741 ttgcaaggat tactggtgca tttttttcgt tagcactctg tactactgct ttaagtattt
    19801 gcccacttcc tatattaaat gctggcacag caaattgatt ttcttgtgcc acttttagca
    19861 tttccttcat atttattaac atattatacc tcccgatatt ttaaatttta ggttgaattt
    19921 gattcttgtt aattttgttg ttgtttatat ttaaataata tcagggtaat gacggttcga
    19981 aaataacaat cgttttcctt agtgaaaagg aacttttatt atacactctt agttcctttt
    20041 cactaaataa tttttagaag tctttatcat agttaattat acctctcatg tacatctttt
    20101 cgtcttaagc gttttaattt aataggcttt aaccttacta tatttttata ataaacaatt
    20161 aagatacttt aactataaat ttaaagatac tcatgcaata gttaatgtta tattagagtc
    20221 aaaaaaatta aaaagatatt agctatttag ccaatacctt ttcgtggatt tcaatagtat
    20281 atacgattta tatgaatcat actcacgctt atctaatgtt ttacttccat aaactttaca
    20341 caaaacacca aaatgacacc ctccaaattc atctctagct aataaagtga tttggttttc
    20401 taagcaccaa tttataaatt aacctttatt atcttatgta aatctttttc tatctaattt
    20461 aaaaattatt cctaatgcta tatagcatat accaattact aatacaccat aagccataga
    20521 tactcctatc ttaaattctt gcatattagt tacaatagaa attgaaatag gtctattata
    20581 aacaccataa agcaaggctg acattgtata ttccccaatt gtacgaatga atactaatat
    20641 agctcctgaa attattcctg gcatcatatt tggtactatt acattataaa aggtttttat
    20701 ccttccagca cctaaactcc ttgatgattc ttctagtcct aaatttattg acttcatagc
    20761 aacctcattg gatgaaaata ataatggtag ggcataaatt gtatatgcta taggtacaat
    20821 ataaaaacct cctattaagg attcattaaa agcaaatata cttttttgat taaatgtatt
    20881 aattaggtta actgcaatgg cgcttgcagg catactccaa ggtagcatta taataaattt
    20941 tgctagtcga ttatatgtag tatccttctt aattactaaa tacgatactg gtatagtgat
    21001 tatcaatcct attactactg ccattaaaga cattttcaag ctgtttaata taggctgtaa
    21061 cacacgtgat ttttggaaaa tcatctgata gttttccagt gtaaagtctc taggaaatat
    21121 agttgtcata attgaatgtg tgcttacaaa ggataaatac acaatagtaa ctataggaag
    21181 catgatcata acaatttgta tttcaataat aaccttacat acaaatgtaa ataagtcttt
    21241 ttttctatta tgaactttat aaccttgaga ctttaaggat gctactactc catatttttt
    21301 tccatagtac tgtaataaaa tcataaatga aatccccatt agtaacaaaa taattacttg
    21361 aactgaagct atatccatgt ggttattagc cttagaccta acaatctgag tgcttaaaac
    21421 tttaaaacca ccacctataa gatttggtgc tgagaaagaa ctaatacctg atgcaaaagt
    21481 tataatagta gaggttataa tggcaggtgt aataacaggc catattacat caaaaaatac
    21541 tcttatcttt gatgctccca ttccttttgc agcttcaact gttgaataat ccacatattt
    21601 taaggcaaca tatacattta aataaaaata cacatactga gtataggcaa ccacaaataa
    21661 aactcccttt aatccactaa aatcataagg ttttttgata aaggatagta aaatttctat
    21721 agattttgtg actatcccac tttctccata aagctgaata catgcaatta ccataattac
    21781 tccaggaatc atcattggac ttagtaaaag aatatgtatg attttcttgt gtttatcaca
    21841 aacaaatgtc atatataagg caagtgatat tcccataatt ccacatacga gtacagaacc
    21901 aaatcccaaa attatagtat tgcttactac ctttaaatta ttagtatttg aaaaatattc
    21961 tttaaaaact tcaaaagaat atccaccttt accttgaaat gcttgtgtaa aggtattgcc
    22021 tattggtatg ataatatatc caatcaaaat ccaaaataat atactgtata aaataatcga
    22081 aataacattt ttaggtgtaa atttactacg ttttattttt ttaatcatat tagttacctt
    22141 gtagcacacc taaatatgcc atatccccta cgtttaattt attgctatta ttcagtctat
    22201 taagttcagt tacttgatat ttttttccat tatttgatac tgtatattct aaaattgctc
    22261 ctaagaaatt cttagattct acttttactt ttataaaacc actttggttg gtattttgca
    22321 ataataccat ttcttcaggt cttttataaa tataaggctt tgtctctttt tcaatattaa
    22381 aattaacata atcttctttt tcaatacagt ttgaagtacc tacaaagttt gctacgccaa
    22441 actttacaaa gggcgaaaac agaccgtgaa acgggctgct gacaacaaac ggcggtatgc
    22501 gccccgtgga ggggtagcgt accgcctttt cttgtggggg tttccaaagg ggtgccccct
    22561 ttggcacacg actttgcttg caaagtgtag tgtgttatac ctgctggcgt ggctgacgga
    22621 ggaaacgggg tgcggtgctt cttgcgcccc gtttgctccg tcaggaaaac aggctgaatt
    22681 tttgcgaatg ggaatgagca aaaaatcggg ctgttttcag agaacggcgg caggtatatg
    22741 aaagcccccg tccctcgtcc tacgctccaa cttgtggaca aagtgtcccg aagttgtggc
    22801 cacactcccg gaaaagtagc aggacaacgg gcaaccgtca aggctgaaat gaacgggttt
    22861 acacccggcc ttgacctccg cccgctgtcc cgctggatgg gtggacaagg cggccaatcc
    22921 ctcaaagtgc ttggccgctc tctttctgat tttgaggtat tcagtttttc aaaattgaat
    22981 aatcaaaata aattttttcg attgaaaaaa ttttatttgt tatcatcttc aatgccatat
    23041 tttttctttt gccgaatcac ataattactg attttttcat catatagtgg atactggtaa
    23101 tccaactggc atgccacttc tgacgaaacc tcccggaaca atgccataca ttgttcaaag
    23161 gattcccaca tatggggata ggaatccata ttataagtgg acataagtcg ttcccacaat
    23221 tcctctggga catattgctt cataaattta tagttttttc ccaaactgaa atgaaatccc
    23281 tgtttgatac caatcagcca ggaaatcatg cgaagcaatt cttttcgtac tatatcattc
    23341 atatggtcaa tagcaaaaag aatttctttg cggcataagc cctttactac atatgttgta
    23401 gtattccaaa attcattaca gcaatcgtca aacattcttt gagtaggctt ctgcaagtgg
    23461 tagtctatat ccgttggtat tggcggcttt acgatacggt tgtctttatc caacagtaac
    23521 tttaccagtt tatcccatgt aaaatactcg tctatcagtt ccagcggcag caaagttaaa
    23581 tctatcttaa catcatcagt aaacagcatt aaatatgaaa atcccttttc tacagctgga
    23641 aataattcca tatcttccgg cttttgcaga atcaaccttt caccaaatat atctagccat
    23701 ttatcatcac ttgtgaagct gtccatatcc gtaacaaaaa aagtaatggc tatgtcacaa
    23761 caaacagttg ataaatagcc atttttatag gggagtatca gaactcccct acaaactgtt
    23821 atttgcagtt atctatactc atttggaatt tcgatatgaa gtgtctcaca caataacttc
    23881 acatcatgtg catcattttc atcaaactcg tatcccagat ggaacattac ttgactatat
    23941 ggttcaatac aggaaacctc tatttcctca attcttcctt tacccgaaaa agtttctacc
    24001 ggaaaacaat ccccatcata aagaatttca ccttcgtccg tatattcaaa acaatgcaaa
    24061 tcaataattc tgtttttcaa atcttcccat acagtatggt tcaatgttgt atattccatc
    24121 ttaatctcat aaaagccatt agctttcatt atttctataa agttctgata atcgttcttt
    24181 tctacaaaaa tgtcaatatc attatgggct cttgactgat atccaagaag agcatctaca
    24241 ccccatccac catcaagaaa gactttaatc tccgcatcta ttgcaaattg aagaatctgt
    24301 tttacatctg ttatattgac catcttatca tctccacaaa ttctaattag gcgaccagag
    24361 gaactgctgg tctgtttgat aaatctctgc atttagcagt tttcaatgtt gccaaaacaa
    24421 aagttaagaa gatgttcctt ttctccatgt cgctttcttt ggcgtaattt acaaggttat
    24481 tccacacaag atagttgttc agatacttgg tagaaacacc gttaaagcca cgcataaacc
    24541 tctttagctg gctatggtag ctattgatat gttggatatt ataaatgcct ttcttggctt
    24601 tgccagtctt taactgcaca aggtcaatgc cattggcatt tgtaaatctc acataggagt
    24661 tcatcttgtc cgtaacaaga gtggaattgg tcttaatcct accatcataa atatgatgta
    24721 aatctcttgt agaaactcta ccagtattcg taatcttgga gatagacaag ccattcctat
    24781 taaccgcaca aggaacacat accttttctt gggacaagcc tctgatatgt gtagaatgac
    24841 cacgcttatg agccttgcgt ggcatagcaa atgtcttact cttgctatga ttgcccttgt
    24901 acgagatggc gaaaaaagtt tcgtcagcct caataatgcc gtcaagggta acatcgtctg
    24961 ccatattctg aagtgcatcc aaaatcttgt gtctccaaag gaatgcggtg tttctgtgaa
    25021 tcccacaagc aacagcagtc ttacgaatgg ataagccatt catcatacaa tcaatgtact
    25081 gctcccacac ggacaagtct tttcttgtac cagacacaat ggagttcgta gcaatcacga
    25141 aggacttgcc acaatcctta catacatatc gctgtgtgcc atctttacga tgaccattgc
    25201 gaaccacatg gatacagcca caaagagggc atacacgacc atttgcaaag cgttcctttg
    25261 ctacgaaatc ttcaatattc aaagacttta caaaggcagg acttaaaagc attgttttaa
    25321 ggctttcctg ctctgcgaca gtcaacttac cgataatatc taatgcgtct ttgatagtag
    25381 gcatatccaa ttacctcctt cggtggtact gtttcttact attattatac gctatttctc
    25441 gtcaaaaatc aaccatttgt tgtgacagag ccaaagtaat atcaaaatcc tgaaaatcat
    25501 caggcggaat atttgtattt gttctagatc cttccaaagt aaccatgcga atgcgtttgt
    25561 ctgtttttgc aaaattcaaa acaatatcat aaacttcctt ttctgatctc atttttatct
    25621 cctccaatta ttgaaatagg tgtgaagcca ttttagggct ttcccgcctt gattaccctt
    25681 tagcaaagac gggcgggact gtcaacggcg gcgcatttat gcgccgttca tcttgaccgt
    25741 tgattggccc cgctaacttt gctactctgt tctaagtaat tcctcaattt gttttttcat
    25801 atattctaca agtgccatcg cttccttttc tactgtctcc cattcatcag acaaatttcc
    25861 caaataagct tcctttgccg ttgttagcag gggggaaaat ctctccggca attttaaaat
    25921 tacccatttt gcggcaacat cttttgtcgt gatttcttct gttactaaag taaaccacat
    25981 tcgtgataag gttaataaca catttctttc atcaccctta aagctggaaa tcaaaccagg
    26041 taaagaaaac cgaattgctt ttttaatttc gtgaaatggg atagcgggaa taagctcttt
    26101 gctttccgcc cccttcaaag ttatgctatt ttttcttgct tgccataata aaatcattat
    26161 atctgggtca ttgcaggctt gcggatattc tcctgcttcc atctctcccc ttagccattc
    26221 accatacata tactgacatt ttggcggaaa ttgcaacgga acaatatcag attgattgat
    26281 aatagttacc tctaaaggtc ttttttcaat acagcctacg gagccagaaa ttttcaataa
    26341 ttgctttgtt agatctgctc tgattgaatt actcaattct tgtttagtaa ttatcagtat
    26401 atctatatca ctatctggac gcagcccatt cattgttgct gaaccatata aatatatccc
    26461 caatatttga ccttgtaata tggtttctgc tattgaaata acttgattta cttgttgtgg
    26521 aaattcattt atattcattg taactcctat atgtatttat ttttactcct caacaactga
    26581 taaaacagcg tctaaggcta attctaaggc tatggatata cttgtttttc cccattctct
    26641 ttcttggtat ttatgagggt ctgcaagagt atcggctgaa aaaagcagca tagcccatgt
    26701 aacttttcta aattttgcac acgccgccaa tgcggaacat tccatttcta ctacttgaca
    26761 tccctcttct ttccgatact gaaccatttc tactgtttct cgataaaaac cgtctgttgt
    26821 ccatgtttta acttcccaat atggtatatt cttttggctt aaagcagatt caatcgcatt
    26881 tataccagcc tttgaaatct ctacttctcg ggagggagga agataatggt aagatgttcc
    26941 ctcatctctc aatgcagaaa caggtatcaa aaatctattt tccgggatgt cttccaatac
    27001 gccgcaggag ccgacggaaa taatctttgt tacaccccct gcaattaaat attctaaaac
    27061 ttggacggca gcagcacttc ccacaggagc cggacataga catattttct cctgattata
    27121 aagacattca taaataggat atcgtcttgt tgcactttca aattcatcta tctgtattcc
    27181 atcatgggta tgtgcataat tttcaacctc gtctcctaaa aaagcaaaca ctgcttttgc
    27241 aggaaaacat tttttcccat ttcccggctg aaaaacagct tttgatgcgg tatcgtactc
    27301 taaaacaggg tagtcatgct ttactaatgg catattatta tctcgaataa caggctatta
    27361 ttctattcct ttcatcatct tttttgccaa ctgcttgaac aggtcggcag tttcttcatc
    27421 catcggcgta agctgtccga tctgtccggc aaccatcgcc gctacatcgt caatggaaag
    27481 cggtttttgt ttctgttccg ccagtgcgtc ccgcatggct tggaacatag cggcggtcac
    27541 agcttctccc ggctgttccc cgttgtctat gtctttctta atgtcccgca ggatagccag
    27601 gaacacattt ttgatttttt caatctccgc ttcatgttcc cccatctttt gggcgttcaa
    27661 aagctgtaaa tcctgcttcg cttctgcccg gtgttccggg tgttctttca tcaggtcgga
    27721 cagggaagcc gttgccatct cgataagctg gtttcttgct gttatgccct ttgccgccgt
    27781 atcctgaaaa taaatccgta tcaaatctat cagcttggga aaattcctgt gttccaacag
    27841 acggttgagg atttgcacat caacagcacc cgtcacaagc cccctcacgg ccccctctga
    27901 caagcctaat tcagaaatat cgtaactttt acggacgctc acggtagaca agcccagtat
    27961 gtagtctgtc gataccttaa attcctttgc cacacctatg agaatatcac tgcttaccgt
    28021 tcttgtttcg ccgctgacaa tgcggctcaa ttgggaagcg gaaacgccta tcttctccgc
    28081 aagttccttt tgtgtgatgt ggttcccgtt gcataaatcg gaaatccgct gtccgggtgt
    28141 tccgggtaaa gccatagaca cgcacctcct ccgcatactt ccattataca agataattgc
    28201 aaaaatgcaa tgtccaaagt gtaaacttca tcaaaatgca attctcgcaa aaagccggga
    28261 tttgcatttt tttcgtgtag acttagggta gttcatcgat ggacagcacc ttgaaaacag
    28321 aatgaccgtc cgaaaagaga ataccacggc tggggaagca ccgccaggag ccggactttt
    28381 ggacactttg tccagaggtc acttcgggac aaaacgtccc gaagctgcgg ggagcgtgcc
    28441 aacgccggaa tacgccgcta ttgtcggggc ccccgcaaag ccgcatggct ttgtggggag
    28501 aggaggagca gcggagcgag tgagttttgc cgcttgcggc gaaacgagcg atacgcagct
    28561 tgcgacgacg aggcaggaaa ccttttcggg gagaacggca atggaaagca aaatggaggg
    28621 aacgcatgag agataacccc tataaagact tgccgccgct ggaacgcagg ccggacggtt
    28681 ccctttaccg catgacaccg gcgcagaaga aacaggcggc cagcctgata cgccgggagt
    28741 gctgttgctg tgagaacggc aactgcattg tccttgacga tggggacacc tgcacctgcc
    28801 cgcagacgat ttctttctcg gtctgctgca agtggttccg ctgggcggtc ttaccgctgg
    28861 acggaacgct ggaagcgggg attttccggg ataaggactt gaaacgctgt gcggtctgcg
    28921 gcggcgtgtt cgtcccacgc tccaaccggg ggaaatactg cccggactgc gccgccagag
    28981 ttcacaggcg gcagaaaaca gaaagtgaac ggaaaaggag gtctgctgtg gacagttagg
    29041 agcgaaaaaa gccttgattt atcaggcttc gcaagcccca aaccggggct ggtggtataa
    29101 agtatcgccc gccccggaaa acgggcttct aaccgtccac aaaacgcact atgacaaata
    29161 ccatctatat ccatcagccg gaaaaggcgt tcagcttcac ccggctcccg aatttcctct
    29221 ttgaagcccc cacattcaag cccttgtcca acgaggcaaa ggttctgtac gcctttatcc
    29281 tgcgccggac agagttatcc cgcaagaatg ggtgggcgga tgattgcgga cggatttatc
    29341 tgtactatcc catctgcgag gtggttgacc tgctccactg tgggcggcag aaagcggtaa
    29401 acaccctgcg ggaactgcaa tacgccgggc tggtggagat ccagaagcag ggctgtggaa
    29461 aacccaaccg cattttccca aaatcctatg aagcggttcc aaacaccgac ttcaagaaat
    29521 ccggttctgg tacgccggag ggctgaaaac cgtacttatg aagtgaggaa atcactcccc
    29581 ggaagtacga aaaccggacg gtatatagaa atacaaagat taaaaagatt tatttatatt
    29641 ctatccattc caatcctatc cgagctaatt tctgcgggat tttccctgtg gaaaaccccg
    29701 gataggaaag gaatggggaa aggagcagaa tggcacaaca cgcaattttg cggtttgaga
    29761 agcacaaggg caacccggca aggccgctgg aagcccatca cgaaagacag aaagaacaat
    29821 acgccagcaa ccccgacatt gacacaagcc ggagcaagta caactttcat atcgtcaagc
    29881 cagagggcag gtactatcat ttcattcaaa accgcattga acaggccggg tgccgaaccc
    29941 gcaaggacag cacacggttt gtcgatacgc tggtaactgc cagcccggag tttttcaagg
    30001 ggaaatcccc aaaggagata caggcgtttt tccagagggc ggcggacttc ctcattggcc
    30061 gggtaggacg ggaaaatatc gtgtcggcgg tggtacacat ggacgagaaa acgccccacc
    30121 tgcatttgac ctttgttccg ctgacaaagg acaaccgcct gtgtgcaaag gagattatcg
    30181 gcaaccgggc aaacctgacg aagtggcagg atgattttca cgcctacatg gtggagaaat
    30241 atcccgactt ggagcgtggg gaaagcgcca gcaagacagg ccggaagcat atccccaccc
    30301 ggcttttcaa acaggcggtt tccctctccc ggcaggcaag agccattgaa gccacactgg
    30361 acggcattaa cccgctgaac gccggaaaga aaaaagagga agccctctcc atgctgaaaa
    30421 agtggttccc gcagatggag aatttctccg ggcagttgaa aaagtacaag gtcacaatca
    30481 atgacctgtt agcggaaaat gagaagctgg aagcacgagc cagagccagc gagagcggca
    30541 aaatcaaaga ccgcatggaa cgggcgaagc tggaaagcga actgcacgat atgcaaagac
    30601 tggttgaccg tatcccgccg gatatactgg cggaactgaa gcggcagcag cggcagcatg
    30661 gaaaggaaag gtgattttat aagtaccagt atcagataca aaaaggaaac agaagtcgtg
    30721 acttttcagg gcagggaaat cacgctggaa aacctctccc cggtgttcac gccggagcag
    30781 gaagcggcca aacgccggga actggagcag cagctttatg aggtgttccg caagtatgcc
    30841 gataagcggc agaaagagga agccggggca taattcccga agccatcgtt gatttacggg
    30901 gctgctggcg gtataataga actgtcagca gctccgtttc ttttttaaga aaaggagcga
    30961 caaaatgaat aataggatag acgcgatcta tgcaaggcaa tcggtagaca aaaaggacag
    31021 catttccatt gaaagccaga ttgagttttg caaatacgaa ttgaaaggcg ggaactgcaa
    31081 ggaatacaca gacaaagggt acagcggaaa gaacacagac cgtccgaagt ttcaggaact
    31141 ggtgcgggat attaagcggg gcttgattgc aaaggtcatt gtttacaaac ttgaccgtat
    31201 cagccgttcc attctggatt tcgccaatat gatggaactg ttccagcagt acgatgtgga
    31261 gtttgtgtcc tctacggaga agtttgatac ctccaccccg atggggcggg ccatgctgaa
    31321 tatctgtatc gtgttcgccc agcttgaacg ggaaacgata cagaagcggg tggccgattc
    31381 ctactactca cgaagcctaa aggggttccg catgggcggc aaagctccct atgggtttca
    31441 cacggagcca atcaagatag acggtatcaa tacaaagaag ttagtggcaa atcccgaaga
    31501 agcggaacag gtcaaattga tgtttgagat gtacgccgag ccaggaactt cctacggcga
    31561 tattgtccgg cattttgcgg agcatggtat taaagatttt tcccgtccgg cactcgcaag
    31621 ccttttgtgc aatcccattt atgtcaaggc tgaccttgat atttatgagt ttttcaaaag
    31681 tcaggggacg gtcatcatca atgacgccgc tgactttacg ggcacaaatg ggtgctactt
    31741 ctatcgtggc cggggaatga aaggcgacac caaacacaat ctgcaagggc atacgctggt
    31801 tatggctccc agcgagggct tggtttcttc tgaactgtgg ctgaaatgcc gaaagaagat
    31861 tttagccaac gccagttatc aggcgggacg aaaggcggtc aatacttggt tagctggaaa
    31921 aatcaaatgt ggcaggtgcc agaaagcgtt aaaagccgag ggcagttatg ggcggtggta
    31981 cttccgttgc agtaagcgtt ccgataacaa aagctgtgag ggtgcgggga cgctccgtat
    32041 tcccgatacg gaagctatta tctatgccgc tatggtaaaa aagctaaaac cattccagac
    32101 catcaagggg cggaaaaatg ccatgaagtc caatccgaag ctgaccgccc tgcaagtgga
    32161 actcgcacaa gtccagcatg aaatcgaaac gctcattgac acgctgaccg gggctaaccc
    32221 catcctgctc tcctatgtga acagcaagat tgaagaattg gatggacgca agcaggagct
    32281 tgtcaaaaag atagcggagt tgagtgtgga taccatcagc ccggaacagg tcaaagaaat
    32341 ttccggctat ctggatacat gggaagaagt ggactttgac gataagcggc gggtggtgga
    32401 tttgatgatt tccgcaattt acgccacaag cgaaagtatc aacatcgttt ggaagatatg
    32461 acggcgcata agcgccgcca tacaacgcaa cctttcgccc tttgtaaact aagctacaaa
    32521 gtcattcaat ggttttttgt aaacttccat tggaacacca atttgaagaa ccttcccctt
    32581 atccattaca gctattctat cagaaatagc taaggcttcc tgttgatcat gagtaataaa
    32641 taaagtagta atacctatct tttgttgtat ctctcttatt tcttccctca tcttgattct
    32701 taaagctata tctagattag acattggctc atctaataaa agcatagtag gttcagtcgc
    32761 taatgacctt gctactgcca ccctttgttg ctgtccacca gataactcat caatcttttt
    32821 tttcctaaaa tctttcattc ctgccagctc taaataatta tcacattttt cctttataat
    32881 ttttttagac agttttttta ttttcaatcc ataagataca ttttcttcaa ctgtcatatt
    32941 tggaaacagt gcatagtttt gaaaaacagt tcccatattt ctattttctg gttctaaatt
    33001 ggtaatattt ttatcaccaa cataaatact tccagaagaa ggttttataa atccaccaat
    33061 tattcttaaa atagtcgttt ttccacatcc agaaggacct agtaaagtaa aaaactctcc
    33121 ttccttaata gatatattaa tatcatataa tactttttct tttccataat aatgattaat
    33181 ttcttttaat tctatattct tcatatcgtc tccacaaatt atctaatatt tataaatctc
    33241 caaatataca catgacgaat catcatagat tttaaatcta ggaaactcta ttgccatttc
    33301 atcatccttt tctagttccc taacctttct atatatataa tctatacctt taatctctgc
    33361 tattttcatc atttcatttt tatcaaaaat cttatatcta tcatatccac atgaaaaacc
    33421 atcactagcc atcataattt tcattttata ttctatatca ataaatccac ttatacaatt
    33481 atcaacagcc tctttagaaa attccaaagc ccaatatcca cctacagtat ttttcttaag
    33541 tctattctct attataatcg gcattacctc ggcttttctc tcctttaaag taaggtttgt
    33601 aacatctttg gcttcttgca taaaatcaaa tattttttta tcaagtctac ataaagtctc
    33661 atcttttaaa attttcacag attcattatg gttaactaat aaagtacaat ctcctaaaag
    33721 taaatactct atcttatctt tataaaactt taatatagaa catgaacaag aaggaatatc
    33781 tattgcttct acttctttat catatgttaa tttgtagtac tcttttgtta tctcctcaat
    33841 gccttcttta ataatcactt ttaagctatc ttctctttcc atattctcat gaaggtaact
    33901 attccaccaa cttacatacc atttagcatc actttctgta gagactaaat tcttattatt
    33961 taaacctgta gctccatcaa gtacccatgc cccataaggt gataaaccta cgatatcttc
    34021 gttaaaatcg ccattacctt tattacataa taatttataa tcactaattt ttagtcccat
    34081 ctttatctcc ttgcccacat aaattgtact tttactataa ttaaaagttt tacataataa
    34141 aaaatttact ttatttaaga aactatgtct acaaatcact ttatatagtc aattacttcg
    34201 ttagttgctc aaaaactatt ttatttaata aatatgtatt agtatcattt gttgtatgaa
    34261 ttataaaaaa ttatgagatg ctatagttcc cttataagta aaatagcgag gaaaatcctc
    34321 actatttttg tatataatat taaattattt aattaagcta ttttatagtt ttattattat
    34381 ctattatatc tgtttcccac ttttcaatcc agttagactg attttttcca attacagacc
    34441 aatctacatc catagcttta tattcttttg acatccactt tggtgaatct ttaagtgcag
    34501 aatctaatgt tggaatacga ttaaaatcat ttgcaaccat agcttgaacc ttagcacttc
    34561 caacaaaatc tacaaattta gctgctgcat ttggatgtgg tgcatttttt agggctgcta
    34621 cacagtctgt gattactaca gaaccactct ctgcatctac aacttctaat ggcatattat
    34681 ttttttcttt attctctatt atatcactta atactgcaac agatattgca gcttcacctt
    34741 tacctattgc tgaatacatg acacttccac tattgtagta attctttata tttttattta
    34801 aatcctcaag atacttccaa gcttcctctt cactcttagt atttgagtag taattgatta
    34861 agttactaat agtagaacgc atagatgatg ataatgagtc tctagtaact attaaatctt
    34921 tgtattcttc ttttgttaaa tcgctccaat cttttggcac tttatcagct gataatagtt
    34981 ttgtgttgta aaaaatcatt actggtgttt ttatagttcc ataccaatat ccatctgagt
    35041 ctttgtaaga cttgtctaat tcattattcc agcttggttt agtcttttca tataatcctt
    35101 cttcttttaa ttgcatgtat gtagatgtat ctccaccaaa cattatatct gcttgtggat
    35161 tatctttttc acttctaaca cggtctgcta attcaccttt taagtttata aattcaacat
    35221 taactcctgt ttcctttgta aattcttcag aaattgctcc tagcatatcc tctccatgtg
    35281 tagtatatac tactaatgta tcctctaatt tatcactttt tgatgtgtta tcattgctac
    35341 aagctacaag tgataataac attgctacag ttaataaaac aactgctatt tttctcttca
    35401 tattgattcc tcccccatat tctccatgtt cattttaaat gttattattc ttgtagtcaa
    35461 tgattcaaca acaatctata taattgtgtt tttctatagt cacttatttt attattgttt
    35521 ttttctataa ttatacctat ttgtatgcat ataattttta tattcacctt aatccatttt
    35581 ttagtatgag tatttttcta tttaaaacac actttaaata ttaatattac tatcatatca
    35641 ttatttaaat tgtacccatc ttttaacaga taactagata aaaataaata ttgctttata
    35701 cttatatcct ttgatgtatc aatatttgac aaatcagctt tcccattgct aataatccct
    35761 ttgtatatta attcatctca ttaatttaat atgttatctt tatttctcta taattccaag
    35821 tctttacata cattataagc tacattttta atctatataa tattcttatc tcattacttt
    35881 tattttctct aaataaatgt atagctcctt atatataatc taaatgtata tgtatagata
    35941 caataagata taaagatttt ttattcttat tcaattccac taatttagat ttagtatgct
    36001 tataataagt atctttcatt tcacagtcta taaatatatt agtttcttca ccattaataa
    36061 ttactaaaaa actatctcca caataatctt aaaacattgt aattttatac tagttcatat
    36121 attaattttc tctaaaagct aaataaattt gtataatatt ctatatatta aatcatatgt
    36181 atcccaattt ttaactttac ctcttcaaat ttatattcat ttttaataaa aaaatattga
    36241 ctatttagtc aatatctttt agtagattta aatggtaaag actatcctga gaatcatacc
    36301 cacgatttta atctaatttt taatggtttc cttagcataa tcttataaat attaaaattt
    36361 atctacttat aaaatttctc cattaaattt tattacattt ttataccaat caaaagactt
    36421 ctttttatat cttttaagag tcccacttcc atcattattt ttatctacat atataaatcc
    36481 atatcttttt ttcatttctc ctgttgtaaa tgacactggg tctatacatc cccaaacagt
    36541 ataccctata acatcaactc catcaatttc aatggccttt ttcatttccc ttatatgact
    36601 agccaaatac tctattctat aaccatcatc cacagtatta tctgatttta atacatcctc
    36661 tgctccaaat ccattttcaa caataaatat aggaagttca tacttatcat ataattgatt
    36721 aaggtaaaat cttagaccta cagggtctat attccacccc cagtcagaag tttttaagta
    36781 tggattttca actacatcag cctttcctgc cgagtcatta cctgttgttt tcatagtttt
    36841 atcagctgat actacagtag ttaaataata actacatcca ataaaatcaa ctgttccttc
    36901 ttttaggatt tttttatcct catctgtaat atctaaatta taattttttc tttcccataa
    36961 ttttagtgta tgccttggat aatgacctct tacatgtaca tcagtaaaca taagttgttc
    37021 tctattagat tctacaaatt taatcatatc ctctggattg caagaataag gataacttgg
    37081 tatagctgcc accatacatc caattttaaa ctctgggttt atttcatgac ctatcttcac
    37141 aacctttgca cttgctacaa attcataatg aactgcttga tacataactt cttctttgtc
    37201 ttcctgctct tcatagatta ttcccgagtt agtaaatgca taaataggat ttgtagttat
    37261 actttgatta tttatttcat tgaaagtcat ccagtactta actttatcct tgtatctact
    37321 cattaccact tcacagaagt ttacaaagaa atctattaat tttctattcc tccatccacc
    37381 atagtttttc actaaatgat aaggcatttc aaaatggctt aaagttatta ctggctctat
    37441 attgtatttt aataattcat caaataaatc atcataaaat ttcaatccat cttcatttgg
    37501 aattgattca tctccatttg gaaaaatcct agtccaagca atacttgtcc taaaacactt
    37561 atatcccatt tcagcaaata atctaatatc ttctttataa ttttcataaa aattaatggc
    37621 ttcatgatta ggataattta agccctcaat tactccatct gttacctttc ttgaaatagt
    37681 atgagtacct gcagtcatca catctgcaat acttattcct tttcctcctt tattatatcc
    37741 accttcaact tgatgggcag caactgcccc tccccataaa aattcttgat tagatttcat
    37801 agaaatatct cctccagtat aattaataaa caacttttat tacaggtgtt ccaattttaa
    37861 tatgtttatt ttctttaact attacatctg ctaaatcatt tgtgttggtt agtattattg
    37921 gtgtaacaat actataccct tcaccttcta ttttatcctt atcgaaagaa acaatcttat
    37981 ctcctttttt aactttatct cctgcattca tatgagtaat ataatacttt ccatctaaca
    38041 tagtagtgtt aagacctacg tgtattaata tttctacacc tttatcagaa gtaattccta
    38101 ttgcgtgttt tgtaggaaaa atagttgtta ttgttccatc tacaggagat acaacttctc
    38161 cttttgaagg tattattgcc atgccattac ctatagttcc tgatgcaaac acttcatctt
    38221 ctacttcaga taactctatt tgtaagcctt ctattggaga taatatttcc tctataccat
    38281 catcttcatc aaaagcaact tcttcattac cttcttcaca ttcttcttta ctcaatccaa
    38341 agaaatatga caatactgct cctaacacta gtgctgttcc tattcctaat atatatccta
    38401 gaaatggtgt ataaactggc attgagaata tattatggaa tacatatgca ttacaagtaa
    38461 cgccaaatac gccacatata ccaccaccaa tacctcctgc aatagccaat actggaatca
    38521 tccttctgta tcttaatata attccataaa ttataggttc tgttactcct gctaaaattc
    38581 ctgtaactgc tgttgaacct gctaatactt ttaattctga atttttttta gattttctaa
    38641 ccttcataaa taaacctatt gcaataccta tttgagcaaa tactgctgca acagctgcac
    38701 cttctattgg gtctccaccc attgtagcca aattttgtaa agtaattggc gtgaagcccc
    38761 agtgtaatcc taatactgct aagaatggca tagctatacc tattgcagct cctgcaatta
    38821 ctctattaaa ttcaaataat cccataaaaa tatttgatat tacatcccca acattagttg
    38881 ctatcggtcc aaataaaatt acagttaaag gaaccatgac taataatgat atcattggca
    38941 ctaagaacaa ttgtaaatct tttaatataa tcttctttaa aagcttatca acataataat
    39001 aaataaatat agcaacaaat ataggaaaga caccaaaaga ataatcaatt gctgttactg
    39061 gcattccaaa aaagttagca ccaccttttg ctccaattaa agctgtaaaa ttaggatcta
    39121 acaaagctgc tcctatcact ccaccaacat agggatttgc accaagcttt atagctaaag
    39181 taatacctaa gaatattggt aaaaagtaaa atacagcatt tccagctgct gataatatag
    39241 cataagtgct acttgtatca gacatccatt tcataatagt taatattgta agcaatgcct
    39301 taatcatacc tgctccagct agtgcaggta ttaatggaga aaatgcacct gaaattgatt
    39361 caaatattct agaaactatt gaaacttttt ctccctgttc tccagtattt tgaacttgta
    39421 aaacagcttt ttttgtaata gtttcaaagt aatcagttac tttatttcct attactactt
    39481 ggtattgtcc tccactattt actacagata gtacatcctt catttttaat aactcttctt
    39541 tgttagtttt tgaagtatct ttcaacttaa aacgtagcct agttgcacaa tgaactaaac
    39601 taataatatt ttcttttcct ccgacatatt ttataatctc ttcagactct ctttcaaatt
    39661 tcatacaatc tatcctccat tttcataatt ttatgtataa aaatagacct aaatcaatac
    39721 aattagatgt taaaaactaa ttataccaac ttaggtcatg cctgccaaac agtaacaatc
    39781 ctacaatatt tactttatat ttgataatct atttaaatgc aatgttaagt acaacaattc
    39841 attttcgcta attttccatt tatacgtctt ttcaagaaag ttttttactt tttttgcaca
    39901 attgtaatca cttttatatt tcatttttat tatatctaac aatgatgtgt ctacatttgc
    39961 attctcacca cttaattgcc tttttataaa acaccttaaa tgacttataa accttgtgta
    40021 gtcaaatgaa tattcattta tttcaattcc atagtgatac tttatgatat ctaatacatt
    40081 atcaattatc ttagttaaca ataaagtttc ttgcatatct tttgtttcta actgagcatt
    40141 tgcaaagtgt atcgtaataa atgctatttc agaatcagga atatctttat ctagtttttt
    40201 tcttaaatat tctacagctt tcttactaaa tttatattca ttaggatata tttgtcttat
    40261 ttcccattga agtgggcttt gaaatactaa tccttcatcc attcttttta acatgtaact
    40321 tatatgttct gataatgtga ttaatatact atcattaaga ttatcaccca attcgtctct
    40381 tcccatttga ataatttcac ttacaagctc aacatctttt aaaggtatcc tatctagtag
    40441 tgaatgtaat tcacttaacg attcctcatt attgaatata aatttctttt caattttatc
    40501 tatttcaact aaatctttag taaatttatt aaatccaatt ccttttccca ttaatattac
    40561 ttcttgtcct gaattatctc tggcaaatac aacattatta ttaaatactt tctttataac
    40621 cataaactac ctccaatgta aacaaaaaga gacctaaaaa agactaataa tactttaagc
    40681 atttactaga atttttaggt cacgcctgat tacttctatc tcagtaacga tccgtttatt
    40741 tatctgtatg ataactttat tttcattata aattaataac tgtacttagt caatatataa
    40801 ttcatgtata tatctaccta tattattttc ttcaatattc actcattcta ctttttttca
    40861 tataatttat ataacctaaa catgctaaaa taagttttga agttatttca taacaaaatt
    40921 aaactcatat attgtttact atatatgctc gattatttat caatatataa ggaaatcctt
    40981 tatttttgta actacaataa ctgactaagt tttgattttc ttttatcttt tacttcttat
    41041 tattaaaaaa taattctttt actgttgtat ctaaagcttt aaacagttta atcatcaaat
    41101 cattgtttgg attattaacc ttacctaact tactatatag ctttttaact gcatatcttt
    41161 aatagacctt ttggtatgct aatccatttt ataatattaa ttcttgaatc aagcatatat
    41221 tacccttaca atgcatatct tataccctct gtaaagttat tcctgaagaa attactctta
    41281 caagacatat ctgatacaac ctcacttata agtttatatg tttcagaagt atataaataa
    41341 cccatacttc cttccaaact cttacctgtt ttcttagaaa attctaatag atttccttac
    41401 ataacaattg taacagagtc ttattagatt tcataaaact atacatcctc tttacattta
    41461 aactttaaac ttttatctat tgtttatcaa tcaaatgtat attcactatt ttttatcatt
    41521 tataatactc ttcttcttat cttaaaacaa ttataatcta accttaatca catactatat
    41581 tatataaata tttttaacaa acttaataat taaataacta tattttatta tccatcttat
    41641 aaatgtttat aaactttcca ctattcttgt tcaataaatt caaacaaatt ttctactgtg
    41701 gtatcgaata ctttagcgat atccatagct aacttcaaag aaggattata cttcccattt
    41761 tctaagtgta caatagtctc acgtcttacc ccaactaatt tagcaagttc attttgcgtc
    41821 ataaggaatt tttctctgta ttctttaatt tttgttttca tcaatattgc cacttagtta
    41881 catatccccc ttttatcaaa gtatatatac aacactaatt tagataaaga ctgtatatat
    41941 aaaactgcaa tgaggattat acctgtatct atgtttgata tatttatatt acttgtataa
    42001 ggtgttgcaa agaaaataga tattattact atagaatata tcattatttt tattgcaatt
    42061 ttattaacct ttgatagtat aaattcagat gattcatcga ctaaatcatt atatttttta
    42121 ttataaattg aataacatcc aaaaactatt aaccaactca accctggaag agaagcagtg
    42181 cttggacctt taaaaatata cttagtggct aatacagcta taaaaaaata agttattaca
    42241 agcaactcca ggataagctt tgattttaca ccagtttctg atttagacat ataaaatcac
    42301 tccttaaaaa ttatattctc tatactcttt aattttcgtt tttatcaata ttatcactta
    42361 gttgcatatt ccctttttat caaaatatat atacaaaatt aatttagata aagattgtat
    42421 atataaaata gctaagagaa ttacacctat atccaaattt gatatatcca aacctcttgt
    42481 ataatttgct taaaagaaaa cagctattag aaaaatagaa tataacatta tttttgatgc
    42541 aatatgatca acctttaata acataagttt tgatgcctca tcaactaaat cattatattt
    42601 tttattatac atgaagtcac atgccccaaa atcgaataaa attataaaag taattcaaat
    42661 atttccccct ttaaaataaa cttttttaat aatgaatcta taaaaaatag gatatcataa
    42721 gtagctttga aacaagattt gttttaaatc caagctctga tttagacata taaactcctt
    42781 aaaagttata tatttataac accttatgtt ataaatatat aacttttcca aataaattgc
    42841 aatagaatat cgtaaatatt caataatatc tttataaata tagtttataa aggattttat
    42901 aataaacatt gcaatacagt actaaattag tttattgcat atattatttc aatcatatca
    42961 tttactaact attattctaa tgagcatata acattgaaat ttataattat acaacctaaa
    43021 tgcatcccaa tgtaccctca aaaccttcat tttctgtaac tgaagtataa ttggtagatt
    43081 ttatcactga aataaaaaac actagtcaat aaagactagt attttcaagt attttatcat
    43141 tctttttttt aattcttgga gaagaatcat cagaataata cctacaattt atctatatgc
    43201 aaattctaaa tttaaaataa agtttcatat gaatttacta ttctatgcta tgatacaaca
    43261 gaaaaaacta caatctatga gcggtagctt catataatcc tagttcctac agtaatcaaa
    43321 aaggaagttt attctatatg taactaatga taaattctat tataggagtt attagctcta
    43381 tttgtgttac tataagtagt aattatatat ataataattt tttaacactt ttctattggc
    43441 taaatagaaa gtagtttaga acttaaattt aaataaaatt taagttcacc aaaagaaatc
    43501 tatattagaa accactactc tattccacca gattgtaatt ttttgttctt tatatcataa
    43561 tgctatacca cattaaattt aaaaataaat tttaaattta tttgttacaa ttcattagtt
    43621 caaaaaaata ctttgagtca tgagttttgt aaagatttaa ccatgaattt aatgcttctg
    43681 attcaaaaac ctctaaaagt ttcaatactt gaaacgtaaa ttccaacgga gcaattcctg
    43741 gagctgtaac taaatgttca tcactaacta cagattccat tttataatat ttttctccag
    43801 aataatttgg tactaccatt ttaagaaact ctaaatcatt acttgtatga tttctaaaat
    43861 ctaatagacc ttttttagct agacctaatg tagctccaca tatggctgca actatagaat
    43921 cttgtattaa cgcttcttta gctttttcta atattatctc atgattcata gataaccaag
    43981 tatttccccc tggtaaaatt aataaatcct tactttccat attaaactca tcaactgtaa
    44041 tttcaggtaa aacttttaac ccacccattg ttataatagg atttttatca attcctacag
    44101 taattacttt tagtggtttt aatccttttt taaaatatct tcctgtattt aattcagcag
    44161 ttaaatatgc cacttcccaa tctgacatag tatcaaatac atacatatat acttttctat
    44221 ttttcatctt ttttactcct tatgtaatta atttatatat ctaattgtaa aataacttaa
    44281 ctgacatatt cagtcagtta agttattaaa tttgataata atcaattaat tctagtaaat
    44341 cttcaatcat tttcttccta aggcttagtg gttgaattac ttgtattgtc tttctataag
    44401 gtaaaagtat atttggtatg tacttgcata ttacttcctc ttcaagcata aatattattt
    44461 tattaggtgt tctttctttc aagtagtgcc ctaaaaacca atgttggctt aaactatcta
    44521 aagaatctat actcccttct acaactaatt gaattatact ttgttcatct tttatttcag
    44581 gtataatccc ttttataaaa aattcacttg ccgaaaattc tgtcggtctg ttaaatgtat
    44641 ttgatgtttc tatgatttca ctaatcctat ccactctgaa actacgaatc tcatttctca
    44701 tattacaaaa ggcaactaca taccaattat tattccagtg aacaattcca tatggattta
    44761 taattctata ttttgatttt gctttacgac ctgcatgata gtttatttct acagatagct
    44821 cctttaatat actattctcc aattttttaa gtactgattc tatagatact ttcccaattg
    44881 gttttattac ttcaagggct attaagtggt ttgttaaaat atcttcttgt ttttgatttg
    44941 aatacatttt taactttaat atcgatttat ctaatgcttc gtctaagaag tatccttctt
    45001 ttttagcaaa tagagctgca tgaagtagag atttttgctc ttctatatca aaaaaaagag
    45061 gtgctttagt aaaattattt aaaaggctat acccaccatt atgacctata tctgaaatta
    45121 taggtactcc actcgcagaa agtacatcaa tatatcgata cactgttctt atatttattt
    45181 ctaatttttc agctatctct tttgctgtaa tttttttgtc agagcttaac atccacagta
    45241 tagacatcat attatcaatt ttagccatgt agtttcacct ctttctattt gttatataaa
    45301 gttattatat aacttttgat tgatttttta taaaaaacat tagtaaactg ctaataattt
    45361 atactaagat ttatttcaaa tatttataga tagtcttttt ctatagttaa gttatccatt
    45421 aaactccata gtagtatatc tacttcaatt aatatatttt caactacact tctcgttata
    45481 tatcaattct cttttttaaa gagtttacaa ctgatattta gtttaagatt tatatatatt
    45541 atttttcaaa aacctttcaa tctcaaatta aaacttcttt gttttaattt gtttaagata
    45601 tagaaaaaat cttatcctaa tttatttaag ctaaaattct tatattttaa aattttcttt
    45661 aaaactaaaa tatttattat catctccagc aacaatataa tctactaatt aaatacctaa
    45721 tatttattca tattttcata gcttattagt tataactcca tcttcttgct aaaattaatg
    45781 ttacccaaca tataattgtg gaagtaatta ctttagatac atcagttaat acatctcttg
    45841 gatatattag cactgagttt atagcccatc tacttacaac ttctatactt actggttgcc
    45901 actctgtatc taaacatatt actacaaatc tttctctatc actatctaca aaaagcttct
    45961 tactaatcta taagcattat aagaattact ttttttctag tttcataaag tactactttt
    46021 tttgttaatt taaaaaatct atatctactc ttttaaaaga tgttttcttt ttattcattt
    46081 acctatttcc tatatctttc tgaattgaaa ataataatgt acactatatc aatgtatatt
    46141 gttatataaa taaatgttca gtttctttat ttctagatat tcaattatac tacattcact
    46201 agataacaaa tatagtgttg aacttgtata tatttacttc acctttatat attctccact
    46261 aaattttcct aataatcttt ttaatctatt tgatttaaaa tactctttaa aaaactttac
    46321 ttctttctta ccttcaactc aactatacac acatatccac tataatctgt tgattttctg
    46381 ttatatccat agttttcatc aagaacactg acaatattat tcacttttta agccactccc
    46441 tttgaatatt attacaataa gtttaaatct tctttcttca ataaatatat tatgaggaag
    46501 actatcatct ttaatggttt aatagcgtat aaggatatga atttaaaaaa tctatttttt
    46561 atatcatatg ggtattgttt tttataaaac tggaaaaacc taatagaatc tatgattttt
    46621 taacataacc tccataaatt agtaccaatt ataacttcaa atttaaattt tatctaaaga
    46681 atatacaatc atatttccag actcaacata atattgaatg ttgcgcttgt atttacaaat
    46741 tatcattcta ataaaaacaa ttatacatag cttaaaatca tcttctaaac ataattacta
    46801 aaattgaatt aatgatatca attccattaa tctcttttaa taaaaaattc tcttttctat
    46861 atgaaaatta tttcaaaact ttaaagttaa atacaaaaat gactataaat agatttttat
    46921 ttacacaaat ctatctatag ccactatagt ttatccaata aaataataaa ataaatatgt
    46981 acacaataaa tgttatttac gtcttaagta tttatttatt agatttttaa ttaaaaaaaa
    47041 caagctagtg aacattaatg ctaaatctag cattatattg ctttgatctc ctgtttgtac
    47101 attttgacct gcattactat ctaaactttc atctgtatct atatttatat ctggtttccc
    47161 atccccatct atatctatat ttacatccga tttcccatct ccatctatat ctatatttat
    47221 atccggtttc ccatctccat ctatatctat atttatatct ggttttccat ctccatctat
    47281 atctatattt atatctggtt ttccatctcc atctatatct atatttatat ctggttttcc
    47341 atccccatct gtatctatat ttatatctgg ttttccatct ccatctgtat ctatatctat
    47401 gtctggtttt ccatctccat ctatatctgg tttcccatcc ccatctgtat ctatatctgg
    47461 tttgctattt cctccgttat ctgaatccgg tttgctattt cctccattac ctgaatccgg
    47521 tttgctattt cctccattat ctggattcgg gttatctgga tctggcttat ttggatctgg
    47581 attacctgta tcataacctc ccgagtcagt atctacattt ttatcaggct tccaataatc
    47641 atctactcca tcgttatctg tatctattgc tggacgatta taatctgtat cagggtttcc
    47701 atctccattg gtatctatat ttttatcagg tttccaaata ccatctcgat ttccaccttc
    47761 tgtactaggc ttccattcac ctgtattatc agtatctatg ttaatatctg gcttccaatc
    47821 accacttgta tctatattga tatctggcct tccatcccca tcagtgtcta tatttatatc
    47881 cggaatacca tctccatcta tatctacatt tgtaatatct aactttaact tcttttcatc
    47941 tttactatct ttagtgtaat ttatatcatc tccaatatat tttacagtaa tagtttgttc
    48001 agtattaaga atatgatgat tactatctaa aggtttccat tcaatagatg cagtactata
    48061 attatgactc tcactaacct tatcatgagt ttttaactct actggatctt tatattcctt
    48121 tccattaata tagaattgta cataaccttt tggagaggca caatctggtc cttctttctt
    48181 atcaggtgaa acagtagcat ttaatgtaaa cgtatctgtt ggtttaaaaa catcagtttt
    48241 tactttaggc gtttctacaa ctaatgaagt ttctgtatca gcaggagtaa tttctgcata
    48301 attataatgt gatctatgcc cccaataaga ctcattaaaa ggagctacac tagcatactg
    48361 tttcgatgta atgattaatt gatattttcc aacatcaact tgttttgtaa ggtcatcact
    48421 tcctaaactt gtatctggtt ccatcgtttc ctcatttaaa cgttgagaac taataattat
    48481 atatgttcca tctgtgagtt ttccaccttt aggattagtt actggaatac catcttttaa
    48541 tatccaatct aaaaatgctt tttcttgctc ttttccaaat ggtaatccat cgtatctttt
    48601 attaatcgaa cctggtggag tatttatctc atcaataata aattcttcat actgctttaa
    48661 aaatggagta gttggaccta tatctttaat ataaaaagta tctgatttta gagtatctcc
    48721 agtatcttta tctacaatag ctaacttaac agatacttca gatccagtaa atttatcaga
    48781 gaaccataag taaagaaccc cttgatcatc cgtatagcta ggcgctccat aaggatactc
    48841 ttttccatta atttgcattg taaaatcatc gactagttta gtattaactt tatcttgccc
    48901 taaatacttt agagatactt tgctcataaa aacttttgtt ttcttttcta agtcaccgta
    48961 tgcaactgtt tcaccgctac ttttgaatgt tgttgctttt aatgaaccac ctgttactat
    49021 aacatctcct gttatagcac ttaggtcaaa aatccagtct cctgctcctg tcatataagg
    49081 taaaaccgtt cctccagtta caagtacacg atatcctcta tttgctcctg gattaacaca
    49141 tccatctcca aatgcactac catgtgcccc tccatatgaa tagcaaagtc caccattaat
    49201 tgtaatattt ccactataac caccaccttt gttacgatct actactgatg gacttaatgt
    49261 atgatttcct gatatatagt acgctccccc tattccagct ccatggtatg cgcctttagc
    49321 agttacagta ccaccattga ttgtgatatc tccaccatca ccgatactac ctccccctat
    49381 tccagctcca aatccagtat tatacccttc catagctgta gcatttataa taccaccatt
    49441 aatgataata tttcctccat tttcagtatc tccaccacca atacctgcag cataagaatt
    49501 tccgacagct gttaaactcc ctctgttttt actatctagt agtgtaaggc gatctccttt
    49561 ttttagcttg tccccatttt ctagagttac atctctagga attttcccat tttcaggaac
    49621 tataaattct ccttcaatgt ctctatttac aacagaatca tcaataatta gagtagtact
    49681 ttttccggct cttatacctg gataaagttg atcacctgac tttagtatgt ttttgctacc
    49741 atcttgtaat ataatatgtg catatgcacc accatcttta tctggtgtta aagtaaatgg
    49801 gctattagat gcagttttaa tatttactcc attaaatatt agttccgctt ttacatcttt
    49861 aggtataaca atcctatgtg ttgttggagt atttggatta ttattttgaa ttgtcatttg
    49921 ttttccacta agaatagtta aaacgccact ttcaaattta aaatcaacat ttatttctcc
    49981 accgctaatt ttaaagtctc ctacagaatc atactcttct gcattagtat cttcttctac
    50041 aagtacttca ttagtatctc cttctgcatt tccttcatta gtatctcctt ctgcatttcc
    50101 tgcattagta tctccttctg catttcctac attagtatct ccttctgcat ttcctacatt
    50161 agtatctcct tctgcatttc ctgcattagt atctccttct gcatttcctg cattagtatc
    50221 tccttctgca tttcctgcat tagtgtctcc ttctgcattt cctgcattag tgtctccttc
    50281 tgcatttcct gcattagtat ctccttctac atttcctgca ttagtatctc cttctacatt
    50341 tcctgcatta gtactttctt ctatagtatc tgcgaaagta tttgacacat taaatgatgc
    50401 tactgatcca agtcccattg agatacttaa aatcattgat aatgctttct ttttacattt
    50461 ttgttgcata aattccccct ccccctaata atttttaata tacactgtat acatcctaat
    50521 atatactcta ataattctta atatacactg tatacatcct aatatacact ctaatatttt
    50581 ttaatatata cttaaaactt atatttgtca atgaatatac tgtttttttc aaccttatat
    50641 attataagta tttattattt gctaaataac tacaataaaa attttaaatt atataaaatt
    50701 tatttaatct tttatataat aatacatggg gtaattaatt gaaaaaacta gtaaaaatat
    50761 taataaatat tatttgcatt attacgctaa ttttctctag cctttcgatt tacataaaat
    50821 tatctgaata taaaaaggct gatgaagtat atactgaact cagagaaaac actagcaata
    50881 acaatagtaa acatcaagaa ctttatgata aaaataatga ttatagattc tggcttaaaa
    50941 taaacaacgc aaatatagac tatcctgtag tacaaggata taacaaggat ttctacctaa
    51001 ctcatgattt ttataaaaat tatcttcctg caggtagtat tttcatggat tatagaaata
    51061 actttgaaaa tgataagagt ttaatagtct atggtcatta tatgaaaaat aaaactatgt
    51121 ttggtcagct agaaagtaga aataaaatat aaaggacaaa cttatactta tgaaattttt
    51181 tcagtatata ctgattactt aattggcaga aattatttaa gtatacactt taataataat
    51241 gatgagttta aagattcttt gaattatata accgaaagat cagtacacaa atctgatata
    51301 aaggtagata tttcagataa aattataact ttgtatactt gtaactatga atttaaagat
    51361 gctcgtacta tagttcatac taaattaatt tcaaaaaaaa gactaataag taggtttgtt
    51421 taaatacaga tttacctaca gtctttaaat catataagga tctgtttaaa aatggcaact
    51481 aaaagagcta atggcgaggg gtctattgtt aaaaatataa gaaatggtgt tcagatagga
    51541 tggcgcgctt ctataagtat tggtcgtgat gagaaggaca aacttataag aaaacaattt
    51601 actgtaaaaa cacaaaaaga gttaaaagaa aaattagata tttataggac aaagatgctc
    51661 ttaggctcta tagtctcagc tgataaaata acctttgaag attggtttta tacttggtta
    51721 tttgattata gagcaaaaaa tttaaaacct aaatcttttg aaagatatga gggcatttat
    51781 agaaatcaca aaaaagatac tgaacttgga aaaataaaat taatagattt aagagctaca
    51841 catatacaaa gatattacaa taaacttatt gatgtatata acaaacctgc atcaacaatt
    51901 ataactctaa atacaagatt aaagccttgt ctaacagaaa cagaaaaaca aggttatatt
    51961 caaaaaaatt attgtaaaat gataacactc ccatctgata acaagataaa agaggtacaa
    52021 atattaagta ttactgacca aaaaaaattt attgatagca ttgatggaga taagtttgaa
    52081 atactttttc ttcttgcttt gagtgctggt ttaagattag gagagttact tggtttgaaa
    52141 tggagtgata ttagttttga tgatgaatct ttaactgtta gcatgacttt gcaacgagtt
    52201 actgaaataa ataaagatgg aactagagaa aaaaagtcat tgaacagtat acaaagacta
    52261 aaaattctat aagaacagtt cctattccaa gaaatgtttt agttaaatta aaaagcataa
    52321 aatacaacaa acagaacaaa gattattgtt aggtgatgct tatataaata ataattatgt
    52381 aatttgtaat gatacaggtc ttgctttaaa caataataga cctggtaaaa ttttagattc
    52441 tttactaaaa aaattaaata tacctaaaat taaatttcat gctcttagac atacatatgc
    52501 aacacgatta ttcgaggctg gtgtccctcc taagactgtt cagacattaa tgtgtcatta
    52561 tgactatgga tatatacaca cgttatgcac aataccaagc aggatgctgt ggataaaata
    52621 aatgatattt tttaatgtaa atgaagtgaa attaaattta ttaacagtaa ttaaaatgct
    52681 ataatatgta tattatattt agattaagaa aagtcatata tttaaataca tggcttttct
    52741 taatattatt tgtctacaat atgacagtcc ttttattttg atgaatctag tatctcacca
    52801 aataattttc tatactcttc tgataaagat acatttacaa gttcacacca tatatgctct
    52861 tgaatatcta tattttcaat acaccatact ttataatggc actccttagt tatataaaaa
    52921 tcaattttaa tttcattggt agaattatct tcttgcttgg aacagtattc tttaaatgga
    52981 tactggtttt ttataaaatc tatatgtcta aatgcttttc ttttaggata atatttacca
    53041 tgaataaaag ttgttataat atctttattt gatttaaacc ctctgtctat atatggaagt
    53101 tcttttattt caatatgcca aaactcttca tcaagaatat catcatatct cttttttata
    53161 accataagta gtttattata attatcatta tctccatgaa caataatatt tttcaacttt
    53221 tctagcttag tattagaaaa atcaaatgta catcctcgcc atttttggaa ttttaaaata
    53281 gtactaacat atgcatactt caatggtact gcaagacgtt catctaatct taaataaaaa
    53341 tttgatttat taaaatctat attttgggac ataatttcaa aaactgcagg tataagacta
    53401 tttatattta tttaaaggag atttatcaat aaaaatgtta tataagtaat attttttatc
    53461 atatataaaa ccattttgtt taaagtccaa gttttctatt ttagtaagtt tataatcatt
    53521 tatatcatac atatgttttt catatgaaat tactgactta atatttaaat catcatatct
    53581 aaatctatcc aacacaaaac atgtaacaac acaaaacaat agatcttcat caatggtaat
    53641 attagttgga aattcttttt ccccacatga aatactatat atatctgaat atgccacatc
    53701 cctaggaaat gtataggaaa gtatttactg tgctacaaaa aaataatgtg ttcttttctt
    53761 ggggtcagta atatattgaa atatttccga ttgagttaaa tttctttctt taattagaga
    53821 tttaacttca ttacaaagtt gtttaatata ataaggaaca ccactccaat tcctcacctt
    53881 aagagatttc cataaaggct catctaaatg aaaagtataa taacttgtat tatagtaact
    53941 atctaaattt ttgatatctt gtatcaattt ttccattatt gttatccccc taaaaatttt
    54001 agtctaattg tattgattta cataagcttc tagttgtgcg ctaattgtgt gtctttcaat
    54061 aatgcaaaag ggattactca gtctaaatcc aagtaatccc aatcatttca tcattctttt
    54121 ttcaaaattg gtggagacga atcgtcagaa taatacccac gattaatttt gttattatat
    54181 attaatacta ctactcatta actaaaattt gaattaaatc aaatactaat ttgaaatttt
    54241 caaaagatat attcttgaac tcctctactc catttaatat actatctgca aaatcattct
    54301 tgcttagtgc aatattatcc tcaggattct taatatcaca tactacacac cccgaatcta
    54361 taatagactt ctttccacat ttatttttat cttgacatat tttatcccct aatatatgta
    54421 atcctagttt agaattaaat tcatcgccta aaaataatct tctacctttg tagaatgttt
    54481 ttatttcttc atcagaataa taatgttcta tacacattat tttatcaatt tcaaccctgt
    54541 tatccggcaa tggcaatacc attgatatta cattattacc ccataattta taatttgtat
    54601 tttcatcttt tacttttctt agatccctat cactcaagtc tctatcaaaa acacatatta
    54661 ccttattatt gttccttaat ttacttgccg cttcacaaat atttattaaa ttattatagc
    54721 ccatttttat atcattttca tactctaaaa attcaatatc taaatcatga tataatcctt
    54781 gctcttttaa ttttaataaa ccagctttca tatgtttcca atctgtcttt ccttctgtaa
    54841 ttattaatgt ctttccattt ttacttttta atatatcttg tatatctttt gaaaataatt
    54901 cagtcctctt ataatattca tatgatcttt caaattccga aaactcttcc ggtccaatgt
    54961 tctctcctgt tggcatttca tatatcttaa atccatcctc tttaaatata tctttcatac
    55021 ctaatataaa taatggagaa tgagatgtta ttataaattg aacctttgga aactttttta
    55081 ttagttttgg tagtacgtcg cattgtatac tcgaatgtag atgtaaatca atttcatcta
    55141 ttataacaat accttctatt tcatttaatt ttatactctt attaatatct ccataatctg
    55201 aatatctaat tattgttgaa aacatgttaa ataatgctga ctctcctgta gataaagcat
    55261 ctaatgtagg tataatcatt gaattggtcg acctatcaat tatattaaat ctggatccac
    55321 ctgaatttct ccaatttaat ccaaacttaa catccttctt tactatttca gataatattt
    55381 cttccacatt ttctcttgct atttttagta atcttatatt atttaagtct tgttccgaat
    55441 tccatccacc taggtcactc tgtattaaat cagctctaga atctacaatt atatctaaaa
    55501 gccatttaat attagtttca gttacatttt gtacgattat gggtttattt aatttaccag
    55561 atattttatc atttattgtt ataagatttt ctgagatgat attttgattc atccagtgag
    55621 gtgtttcata tctattcgga ggaaaaaaac aaaaagattt atttgcaaat tcttcctcaa
    55681 aatactcttt atttttagtt atatctttta tattttttct attaccccag ttattatcta
    55741 aatttaatag tccactagtc ttttctatgc attgctcaaa tgataagttc cctaattttt
    55801 ctatatattg aaaattttgt tctccattta caaagttgat aaatgaaaaa gaataatcac
    55861 atccaacctt tgtgtttttc caagataaaa ctttaaaata aggtgttgta ccatctttat
    55921 ttgtttctgt tatatcattg tacggctgtt ttgcaaattc aaataatgaa tcaactatgt
    55981 tgcttaatac agttgattta ccctttccat tttcacctac aaatataatt ggttttggac
    56041 ttccatcttc attgaatgga aaccctatat ctaagttatc tataggtcct acattctcca
    56101 ttattattct gtctaaaaac atttactatc ttccccttta tatatttata ttaaaaaagt
    56161 attgatattt atatcaatac ttttcgtgga tttcaatggt ggagacgagg ggagtcgaac
    56221 ccctgtccgc aaatcttttc cttgctgcat ctacatgctt agccaacttc actaatatct
    56281 cacctcacat agcgccaagt ggcaggctct atgcttagcc agtcccaatt aatctacttt
    56341 aagtcgagac acccctaaag tagttccctg cataatgacg tccagtctta gtcggcagga
    56401 ggactaagag ggacgagcag caactaggct gctatcgcga aattatcgtc tgcgtttatt
    56461 ttaaagttcc ccagttttta cgtgacccag agtaacacga catgcagcct caagttccaa
    56521 acccacgtcg aaacctttac gcccccttga gtaatttata gtccagtaga ctcttcgcaa
    56581 actttatcac catttttatt aaatttttaa tgtatatata atataatact tttaagaata
    56641 aaaatcaatg ttatgttcta gataataaag aattttattc taaaaaatac agttttatct
    56701 agtttaatac ttccccgtca tttctctttc tatacgtctt tgtgcatctt tcttagccat
    56761 atcttgacgt ttatcatata gttttttacc ttttgctaat gcaatctcta ctttaacctt
    56821 accatttttt agatacaaac tcagtggtat aagtgaatac ccctttatag tagttgctcc
    56881 aataagtttt cttatttcat gcttatgaag caataatttt cttactctta aagaatcaac
    56941 attgaatata tttccttgct catatggact tatatgaact tgttttaaaa atacttcact
    57001 attatctaca gatgcaaatc catcacttaa gttaacttta ccttgtctta ttgattttac
    57061 ttctgtccct tttaattcga ttccacattc ataggtttct tctataaaat attcatgtct
    57121 tgctcttttg tttgttgcta atattttttt accagccata taaatctcac cttctttgct
    57181 agaaatttct tcaataaata ttagaaattt gctaaatatt tattgtcacc aaattatttg
    57241 actaacttgt atgataacat atttaggcat tttagtcaat atttcactga tatattaagt
    57301 tatttaggtt atatataata aacaatataa atatataaaa ataattaaaa aactatttga
    57361 aatatactta atattaaact acatttaacc agtaacacta ctttataaac ttcaaaacaa
    57421 aaatattaca tattataaat tttctatt
//
LOCUS       DBGJFK010000018        56157 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.018, whole genome shotgun sequence.
ACCESSION   DBGJFK010000018 DBGJFK010000000
VERSION     DBGJFK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.018"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            306..935
                     /locus_tag="ACOIAP_001327"
     CDS             306..935
                     /locus_tag="ACOIAP_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638226.1"
                     /translation="MNKYLLINPVAGRMYGEKFHLVKENLMKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESINLLKRNNLINSFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLIVTCPCTQLRDFASEKFKDKSNAIFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGSEDKYDIVEMFYCKDGCNNGDGL"
     gene            936..1718
                     /locus_tag="ACOIAP_001328"
     CDS             936..1718
                     /locus_tag="ACOIAP_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638227.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGIPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVDAYE"
     gene            1711..2589
                     /locus_tag="ACOIAP_001329"
     CDS             1711..2589
                     /locus_tag="ACOIAP_001329"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638228.1"
                     /translation="MNNLVCDSGYIIRNLSKSYEVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLENINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     TFHNQRKNTILNKMLRKFKHNKRVIGKIINDNFRSLETNENLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLFMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDDYNRDLTSEYYI
                     KLKKDILMTMKSNKGI"
     gene            2622..3581
                     /locus_tag="ACOIAP_001330"
     CDS             2622..3581
                     /locus_tag="ACOIAP_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2638229.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSIDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYV
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3895..4587
                     /locus_tag="ACOIAP_001331"
     CDS             3895..4587
                     /locus_tag="ACOIAP_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGZ2638230.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSNIRRVYGEYSTKIDERIVELDGLKFYPERLELELHSKNLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     IRGLGYKLNKNW"
     gene            4828..5601
                     /locus_tag="ACOIAP_001332"
     CDS             4828..5601
                     /locus_tag="ACOIAP_001332"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGZ2638231.1"
                     /translation="MYLGSSFLGRNISVILKQQHKLYQSMIQEHKKIHGEHLTFINQW
                     IHQMKTPISVISLQLQDYEGEEVTENIREEIDRLNKGLDMAMHFARADNFQKDFIVEK
                     AKLNEIVSSIVNEEKRLFIKSGMIPKIQIDKFTYVYTDVKWMKFIIGQLVTNGVKYSK
                     DCSNYITIKSEENNKYVILSIIDEGIGIVSKDLKRVFDPFFTGENGRKFGESTGMGLY
                     LVKKVCDDLGHKVSIKSEVGKGTEVSISFNKDVNSLIKM"
     gene            5837..6688
                     /locus_tag="ACOIAP_001333"
     CDS             5837..6688
                     /locus_tag="ACOIAP_001333"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGZ2638232.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVREFLKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSVMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAIYRIIMGAVLAVLA
                     LTNIISI"
     gene            6822..7568
                     /locus_tag="ACOIAP_001334"
     CDS             6822..7568
                     /locus_tag="ACOIAP_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638233.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKDKNLLLLKGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDRRLNEVSEILGIKDLLGKRTFEVSGGQAQRTAIARALINR
                     PSILLADEPTGNLDSKSSKTVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     AIYNEIYKGSSREQFYQDIMDVLTLLGGDN"
     gene            7568..9484
                     /locus_tag="ACOIAP_001335"
     CDS             7568..9484
                     /locus_tag="ACOIAP_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2638234.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASITISSSLLFSFVMFTSHPDL
                     DLSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISNRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSLFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAVTST
                     DQYTTYLRLVPVTSLTIAATYLFFSQFSVFFIKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVKRQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMRFIENNLKKEDIDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITEVIG
                     VKPISFEDNESISLLSSSLPGNKKIKENVTVGNRSLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFDNESGMQPYLFFSKELMIET
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLLPYVVAVIHSIFALTALKNSFDLEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIKLNLVNY"
     gene            9766..10680
                     /locus_tag="ACOIAP_001336"
     CDS             9766..10680
                     /locus_tag="ACOIAP_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638235.1"
                     /translation="MILIQSRGKMKCKELAEELEVSERQIKSYKMYLEQAGIFINSTP
                     GIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKTEFNSIVEKIKAVLNT
                     RVKSDTYMDYFTIQPQRNCDYKFEKNKCNEIIRAYTTKRKLWIEYYSLNSGNSERIVH
                     PYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKNYKVLEEKYNVDKSFSWDEYSKNSIG
                     IYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWILS
                     MGAYVEVVDPDSLRNDILSEIEKMKKIY"
     gene            10758..11495
                     /gene="cas6"
                     /locus_tag="ACOIAP_001337"
     CDS             10758..11495
                     /gene="cas6"
                     /locus_tag="ACOIAP_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HGZ2638236.1"
                     /translation="MKMKIEFSTSCIPISYNSLFMSIIKEAIKKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYVKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGSGLKRKLEFENIDLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNIIYNLGLGFRRAQGFGDVDILEWR"
     gene            11501..13351
                     /gene="cas8a1"
                     /locus_tag="ACOIAP_001338"
     CDS             11501..13351
                     /gene="cas8a1"
                     /locus_tag="ACOIAP_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HGZ2638237.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKSNKQAEIFIMEDYIEFDSS
                     FLENFHEYYFNYFMDEYDVSKRIKKSIDYSINFIKSKPDKVKDGIKKIKDTVKQQNDK
                     VKKFDEEKFNLIKEKLDSISKIKSYDEFDSLEILVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDISEKKVSKSSVNTIEKIMKEINKNFIKKNKSIENIKEYMDSLEICEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWKQEYVSSICDVCKLILFCTPAGATYTR
                     KDYLTNEENEFYLFVNMDTSINELFDRNNSLKAQKSESSNSKDENPFNQLIKSIVEEN
                     KLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSN
                     VLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVY
                     KMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFS
                     PSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLSNEKEEK"
     gene            13353..14267
                     /gene="cas7i"
                     /locus_tag="ACOIAP_001339"
     CDS             13353..14267
                     /gene="cas7i"
                     /locus_tag="ACOIAP_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HGZ2638238.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRADGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREAAVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGEIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVVQGTFLGKYLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            14269..14970
                     /gene="cas5b"
                     /locus_tag="ACOIAP_001340"
     CDS             14269..14970
                     /gene="cas5b"
                     /locus_tag="ACOIAP_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5b"
                     /protein_id="HGZ2638239.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LKEIYDSLLNYNEHLSLGRKEDLVRITDIRFVEVNKFEIDEDIQLDDYENYKLSECDI
                     RMPIYIPKTSLQDKDIDGISYRLNNYYDNNAVGDKKRVWNKVDSYYVEDGNTISVGDI
                     LLDNEGDLLYFNNIN"
     gene            14981..17302
                     /locus_tag="ACOIAP_001341"
     CDS             14981..17302
                     /locus_tag="ACOIAP_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HGZ2638240.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGTNINSLNFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIISRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDKKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVMN
                     IGEHTENYLMKEFGSLRETQSFAQSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGKFMIMTATMPTIYIDELKKRGVVDSNLANLTCNTEKIRHCVSIVENSIDENLEQII
                     QSGINKKVLVIVNTVKSAIEKYELIEEIIKSKGIDINVNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKNCMNGKKCFKMKEKHKVQMVKILYSKESLKD
                     TDFEKKFTRALDILDTITPYSLGSNEAQNILRNIEGYTVIPEDIYRKIEKTLIRDYEE
                     LGQELTEAYSNDDRQLINEIKSKRKKARREIIKKTVNLPIYKAKQNIVDIQVKGLEDL
                     KILLYKYDIHEDVHTKHIFGKGVIIGKEIDQFI"
     gene            17350..17868
                     /gene="cas4"
                     /locus_tag="ACOIAP_001342"
     CDS             17350..17868
                     /gene="cas4"
                     /locus_tag="ACOIAP_001342"
                     /EC_number="3.1.12.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HGZ2638241.1"
                     /translation="MPIDLDLLKVQGVKINYYYVCKRKLWLFSKGITMEQNSSRVLSG
                     KIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEMQLYYYLYYLKN
                     SMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMKLSPPKIEKKPYCTK
                     CAYYEFCFVKEE"
     gene            17871..18851
                     /gene="cas1b"
                     /locus_tag="ACOIAP_001343"
     CDS             17871..18851
                     /gene="cas1b"
                     /locus_tag="ACOIAP_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1b"
                     /protein_id="HGZ2638242.1"
                     /translation="MYKDYYIISNGNIKRKENTIYYYNLEGDKKILPVEQVDDIHIYG
                     EVDLNTKLINYISQYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDAIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            18854..19120
                     /gene="cas2"
                     /locus_tag="ACOIAP_001344"
     CDS             18854..19120
                     /gene="cas2"
                     /locus_tag="ACOIAP_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HGZ2638243.1"
                     /translation="MFVIVTYDIVEAKSLNRIRKILRKYLTWTQNSVFEGNITDGKLH
                     KCISEIENIIDNREDSIYIYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   19304..21425
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19304..19332
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            21486..21914
                     /locus_tag="ACOIAP_001345"
     CDS             21486..21914
                     /locus_tag="ACOIAP_001345"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HGZ2638244.1"
                     /translation="MIRKLNNKDINKIMEIWEESTIKAHGFISKEYWQNNHNAVKNEY
                     IPISDTFVYDIGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATEKYKSLSL
                     AVYKDNKKAVIFYNKKGFNVVKGQLNEDSGFKEYIMEYSK"
     gene            22050..22217
                     /locus_tag="ACOIAP_001346"
     CDS             22050..22217
                     /locus_tag="ACOIAP_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638245.1"
                     /translation="MVTKEENKIVWCISNLTNLPFKNNKFDIILNVLSPVNYKRFERV
                     LNNYGMARKVC"
     gene            complement(22377..23147)
                     /locus_tag="ACOIAP_001347"
     CDS             complement(22377..23147)
                     /locus_tag="ACOIAP_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638246.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLNL
                     NKDNNLDERPILDELNYNTSSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEISNEVSSIRCCNCDELLEDVTLDKLSNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            23471..24016
                     /locus_tag="ACOIAP_001348"
     CDS             23471..24016
                     /locus_tag="ACOIAP_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGZ2638247.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRKNL"
     gene            24037..25173
                     /locus_tag="ACOIAP_001349"
     CDS             24037..25173
                     /locus_tag="ACOIAP_001349"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HGZ2638248.1"
                     /translation="MEEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKHLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKIKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNINNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIKKAELDFWVKESHKRAKEAREEKIFDDIIFPINNSTCDEGIRDKMSQRLLDRMP
                     SILGKESITNAANSCLINDGASFIILCSKKYLEHAKNKPIAKIVNTCTIGTDANLSPT
                     SAIKAMDKLLEIESLSYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALMIERV"
     gene            25177..26568
                     /locus_tag="ACOIAP_001350"
     CDS             25177..26568
                     /locus_tag="ACOIAP_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HGZ2638249.1"
                     /translation="MNYYELLRIKSDRHKNKNFLIIDGEKYTYENILSYSEEIGKQIY
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNLSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNAIFNISGESILFINGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPIKLQLLVKHLKESVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIERPLSVGRPFPGIDVYIREEKIFVNT
                     EYAVYNATKPYSVNDIGYFDNDGYLIFEGRSDDIVNIGGFKVSSTKIENEVKKIPQIE
                     DAVVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            26644..27519
                     /gene="dpsA"
                     /locus_tag="ACOIAP_001351"
     CDS             26644..27519
                     /gene="dpsA"
                     /locus_tag="ACOIAP_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HGZ2638250.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDNCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAISEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTASAFGYSSISLNQLDEKLLQFDYIFNTI
                     PDCILTKERLEKVSQEVTIIDIASSPGGVDYSATKEVGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            27522..28112
                     /locus_tag="ACOIAP_001352"
     CDS             27522..28112
                     /locus_tag="ACOIAP_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HGZ2638251.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEDAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(28319..28519)
                     /locus_tag="ACOIAP_001353"
     CDS             complement(28319..28519)
                     /locus_tag="ACOIAP_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638252.1"
                     /translation="MKKLKIISIFSLIISVILTIGGIGIVTYYVNNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            29023..31677
                     /gene="adhE"
                     /locus_tag="ACOIAP_001354"
                     /gene_synonym="adhC"
     CDS             29023..31677
                     /gene="adhE"
                     /locus_tag="ACOIAP_001354"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGZ2638253.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIKEAQKI
                     FATYTQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDESADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMDKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     VASFLGLKGNSEEEKFQSLLSAIEDLKFKVGIPKTIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            31953..34172
                     /locus_tag="ACOIAP_001355"
     CDS             31953..34172
                     /locus_tag="ACOIAP_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2638254.1"
                     /translation="MTRRSKSFTLIIILFLTSLFLTMGYIYIEDTKNLLMSEAKIHIK
                     EVAIQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDELENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYADEVNKSIKKITISVPLLNNDK
                     VVGVLYCTYNINTLMKLINVSFYENNSISYVVKNDGTVILHPQEDSISKNIYKLLKQD
                     NDIREVNSLKKELQENKTGATVLKMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSEKIINRAIYAVLFIILIFIAIIFYIIYIKKSNEKEILSLAYEDKVTHIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVFARLSSDYFAIFCDYKNGRNKIIRKLDSIRNNIESNLSIVFEISLCVGIYFVEED
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVNGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFEKVCTD
                     LSEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIQMYNLSSDLIEIEITETVAINE
                     LNILKNVLNELRKYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLDGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            34426..35088
                     /locus_tag="ACOIAP_001356"
     CDS             34426..35088
                     /locus_tag="ACOIAP_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HGZ2638255.1"
                     /translation="MIDVSIDKKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TLNKNLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSEESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            35458..36867
                     /locus_tag="ACOIAP_001357"
     CDS             35458..36867
                     /locus_tag="ACOIAP_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HGZ2638256.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGILFVAYIGMAIFFRNHFYF
                     GTTINGVRASGKTVEQVNDLLTSSTNSYTLNLDERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMVTLSYNKDLLEKRFNALSCLDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEVPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKNITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNRDDIGNTYVEISLSNQHMWFFKNGEMLVSTDIVTGNLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGGIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            36982..37257
                     /locus_tag="ACOIAP_001358"
     CDS             36982..37257
                     /locus_tag="ACOIAP_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HGZ2638257.1"
                     /translation="MNEKLTKILEKAKNDDEFRKELIKSREQRDVMDSFCKVVTSRGY
                     DITVGELFSIGEEYTSNLLKSVNGGATYPIEDWSDWYEDFFIMLSNI"
     gene            37887..38198
                     /locus_tag="ACOIAP_001359"
     CDS             37887..38198
                     /locus_tag="ACOIAP_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638258.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAKERKSKAIEAVIGKVV
                     R"
     gene            38200..40125
                     /locus_tag="ACOIAP_001360"
     CDS             38200..40125
                     /locus_tag="ACOIAP_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGZ2638259.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEEQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDGLRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHAESIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIALVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGVLGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            40128..40619
                     /locus_tag="ACOIAP_001361"
     CDS             40128..40619
                     /locus_tag="ACOIAP_001361"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGZ2638260.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            40671..41234
                     /locus_tag="ACOIAP_001362"
     CDS             40671..41234
                     /locus_tag="ACOIAP_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HGZ2638261.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            41249..42226
                     /locus_tag="ACOIAP_001363"
     CDS             41249..42226
                     /locus_tag="ACOIAP_001363"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HGZ2638262.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKVMSSAILEAFDVYSKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            42219..42536
                     /locus_tag="ACOIAP_001364"
     CDS             42219..42536
                     /locus_tag="ACOIAP_001364"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGZ2638263.1"
                     /translation="MYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVEDEY
                     AIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGADIL
                     FKE"
     gene            42653..44431
                     /locus_tag="ACOIAP_001365"
     CDS             42653..44431
                     /locus_tag="ACOIAP_001365"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGZ2638264.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTIKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            44428..45801
                     /locus_tag="ACOIAP_001366"
     CDS             44428..45801
                     /locus_tag="ACOIAP_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGZ2638265.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            45807..46475
                     /locus_tag="ACOIAP_001367"
     CDS             45807..46475
                     /locus_tag="ACOIAP_001367"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGZ2638266.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDAAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSAAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            46752..47801
                     /locus_tag="ACOIAP_001368"
     CDS             46752..47801
                     /locus_tag="ACOIAP_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_function: GO:0033226 - 2-aminoethylphosphonate binding
                     [Evidence IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2638267.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADVIWGLSAMNMIELKE
                     DGALEAYKPKHYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGAKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPVEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYSHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLSSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            47897..48886
                     /locus_tag="ACOIAP_001369"
     CDS             47897..48886
                     /locus_tag="ACOIAP_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638268.1"
                     /translation="MSYLKIKNVFKNYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGDIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKISKEKIDNKVKEVLEIVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            48891..50609
                     /locus_tag="ACOIAP_001370"
     CDS             48891..50609
                     /locus_tag="ACOIAP_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0033225 - ATPase-coupled
                     2-aminoethylphosphonate transporter activity [Evidence
                     IEA];
                     GO_process: GO:0033223 - 2-aminoethylphosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HGZ2638269.1"
                     /translation="MNNNAIGYKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASETLLNSLKNTIFVSVISTVISLALALVYAYALTR
                     TNLKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGIHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLNSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGIVGIIAFGIISVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFDFMDTIYLKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILITNILVKAIHEFIKNRLE
                     KRTNFN"
     gene            51037..51768
                     /locus_tag="ACOIAP_001371"
     CDS             51037..51768
                     /locus_tag="ACOIAP_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HGZ2638270.1"
                     /translation="MGRAKYYDIYIDLKNRIENKEYLYQDLLPSEYTLIEEYNCSRNT
                     IRRAIQELANQGYVQSKHGKGVFIIYKANKQSEFLLGGTESFKESAIRNKKEYKTKVV
                     HFEEMVIDDKKSQITNFEVGTEVYYIQRVRILENKPSIIDHNYFMKDIVKDINEEIAS
                     NSIYEYMESELNETIVTTKRTMTVEKATKLDKKYLELGDYNCVAVVSNNTYNAQGIMF
                     EYTQSRHIPDGFIFFHQSQRINNIK"
     gene            complement(51784..53523)
                     /locus_tag="ACOIAP_001372"
     CDS             complement(51784..53523)
                     /locus_tag="ACOIAP_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004555 - alpha,alpha-trehalase activity
                     [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalase family glycosidase"
                     /protein_id="HGZ2638271.1"
                     /translation="MNIKEIPFSYFGSYMSISYSDELGFTLKSLRGKSKKNMDVLRII
                     PTVNNMPVDYEFEANYFSILIKFNNGSISICFEGDSKIVFYGKGKNVGLKLDTLPIYN
                     FEYNYLMGKKGSEYCVINSYKNLTKFLVFSVNGKVGLSQNIFIDDCASTNKANNTSII
                     DVKSNSDNEFICVIEDIPTHMKVPDYKEYNFETSLNSTKKLFDEYYLAQPKVDEKYKN
                     SLLKASYINWSSFVKPQGYLKRYTILASNSTFLGAWSWDHCFNALALAGVNDKLAFDQ
                     MAVLFDYQDEYGQIPGSLSDSTIRWNFTKPPIQGLFFSKMMKKINFTKETLEKIYNYI
                     EKQVLFYVKFKDSNMDGIFEYHHGNDSGQDNSTIFKGAMVVDTPDLTAFIINAMDMLS
                     KVAEKLNRNSEKEYWSNKADELTKLFLNYFIVDDLPVARETVTGEILSNNALLPLVSL
                     VLGNRLPKYIRDKMIDLVTSERYLTKWGIATEAIDSDEYQDDAYWRGPIWAPTTLLFV
                     EALEECGENELAIDIAKRYCELVDKNGFAENFNAITGEGLRDKSFTWTASTFIYLAAK
                     VYEYNSQRINNIK"
     gene            53771..55204
                     /gene="treB"
                     /locus_tag="ACOIAP_001373"
     CDS             53771..55204
                     /gene="treB"
                     /locus_tag="ACOIAP_001373"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HGZ2638272.1"
                     /translation="MRKNKILNSKESISKIIEYVGGKENIQSATHCVTRLRLILKDTS
                     KANISKLEDIDIVKGCFNAGGQFQIVIGTGVDKVYKDLIDQTGAEEVSKEEIKQQVNE
                     KSNKFQKFIRILADIFIPILPAIVASGLLMGVNNMIANPGIFYEKSVIEVNTDIAGIS
                     GIINLIANTSFTFLPALIGWSAAKKFGGNPLLGVVLGLVLVHPALMSAYDFAANPSAA
                     PTWDIFGMKVAQVGYQGQVIPVLIATYILAKLELFLKKTVPDAVQLVLVSPIALLITG
                     MLTFVVIGPITMTGANMITNGVVYLFEVAPVFAGALYSFISPPLVITGMHHLFLGVNL
                     QMAGTLGYVTLWPISETVTLAQGAATLAMFFILKNNKNLRGVSITSTISAWLGITEPA
                     IYGINLRFRYPFIAVMVASAIGGAFISYHNVKATAVGVGGVFSFLSVMPQYWGVYFTG
                     MAITFVITIGLTYLFYKSGKFKTNDNI"
     gene            55267..>56157
                     /locus_tag="ACOIAP_001374"
     CDS             55267..>56157
                     /locus_tag="ACOIAP_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGZ2638273.1"
                     /translation="MLDFKKSIVYQIYLKSFNDTTNNGLGDLNGITEKLDYLEFLGVD
                     YVWITPFFVSPQNDNGYDVADYYNIDPIYGTMDDLENLIKEAKKRNIGIMLDMVFNHT
                     SIENEWFKKALKGDEYYKDFYIFKNPKEDKSAPTNWESKFGGNAWEFVEEFNQYYLHL
                     FDKTQADLNWENPNVRKELKNILKFWIDKGIKGFRFDVVNLISKPEKYEDDLQDDGRR
                     FYTDGKKVHQYLKEMCEESGILENDMLTVGEMSSTTIENCVKYSNPDEKELSMCFNFH
                     HLKVDYKNQNKWMLQDCDFIK"
BASE COUNT        22042 a         5946 c         9758 g        18411 t
ORIGIN      
        1 catagcattt ttaaaacttt ctacttttat tagttcgaat aactgttact attaaatatt
       61 aatactaatt atatacatat cattatataa tatttataga ttattatata agtagattat
      121 tagtaaaatg tatgcattat taattaaaat aaattacata tgttatttaa tattttattt
      181 aaaatattaa aaaatataga taaaaattgt tttattaaga aaaaattaat atattgacaa
      241 aatttaagtg ctcatttaaa ctattaattg ataataatat tcaatattaa ataataggag
      301 gagttatgaa taaatatctt ctaataaatc cagtagcagg aagaatgtat ggagaaaagt
      361 ttcaccttgt caaagaaaat ttgatgaaaa aagggtacat aatagcagaa tgtgaaccac
      421 aattagaata tgtaaaaaag cagtacaaag agtatacaaa aaagactgag aatacaatgt
      481 tggattgtag atgtccagaa agtataaatc ttttaaaaag aaataatttg ataaatagtt
      541 ttgaagtacc tatgatagaa ccaatattag taaggacttg tagggtttta tatgataaat
      601 atataaaaag taaagatgat atgctgatag taacctgtcc atgtacacaa ttaagagact
      661 ttgcaagtga aaaatttaag gataagagta atgctatatt ttatacatgg aaagagtttg
      721 ctgagcagga aggtgtaaaa tcgcttggaa aaatagatga atcaccaatt ccattaggat
      781 atttcaaaga tacttttgaa aaagtgcttg aagtatcaag tgaagatgaa atcttaagtg
      841 aaatacaaaa aataagaaat ggctctgaag ataagtatga catagtagaa atgttttatt
      901 gtaaagatgg ttgtaataat ggagatggtt tgtaaatggt caataaattt aataataaat
      961 ttttaaggct agtaaagagt gttctgatat tttttataat tcttttatta tggaaaatta
     1021 caaattatct tggtatttgg agtgattaca tactgccatc acctgaaaag gtatatagta
     1081 catttttaaa tatgataagt gatggttcga tatttattaa tgtatatgca agtatgaaaa
     1141 gagttttgat aggttttgca ataagtactg ctataggtat tcctttagga atattctttg
     1201 gaatttatag tggagtatac gaatatttta aatctctaat aaatttttta aggaatacac
     1261 ctccccttgc tttaatacca atgcttatct tatggtttgg tataggagag gaatcaaaaa
     1321 ttataattat agttttagca tcctttttcc caatctttac aagcacattg aagggtatta
     1381 aaaattgtga ctcaaaactg attgaagtgg gtagggtatt tgagttttca aagcttcaga
     1441 taatatttaa aataataata ccaaatgcca ttcttgatat tgcagttggg ctaaagttag
     1501 ctcttggata tagttttaga gcaattattg gggcagaact tgtagcagcc tcatctggtc
     1561 ttggatactt gatatctgat ggaaaagaaa tgtctagaac agatgttgtt attgtaggta
     1621 taatcgtaat tggactttta ggaataatta cagattacat attttcgatt attgtgaaga
     1681 aggtaagtaa gggaaagatg gtggatgcat atgaataatt tagtatgtga ttctgggtat
     1741 ataattagaa atttatctaa aagttatgaa gttgacaatg aagaacatgt agttcttagt
     1801 gatatctctt taaacataga tagaaaccat ataacagtaa ttttaggtga aagtggttgt
     1861 ggaaagacta ccttgcttag agcaattgca tcacttgaaa atataaatag tggtgaaatt
     1921 aggtttatta atgataataa agagtataga cctaatgttg gttttgtctt tcaggagagt
     1981 cgattgatgc cttggctaaa cgtaagtgaa aatattactt ttcataatca aagaaaaaac
     2041 actattttaa acaagatgct tagaaaattt aaacacaata aaagagttat tggtaaaatt
     2101 ataaatgata attttagaag tttagaaaca aatgagaatt tgaacaaatc aaataaatat
     2161 aataggaaaa gtaatattga tgtagaaaaa tatcttaaga tgatgaactt gcagaaattt
     2221 aaaaactctt atccaaatga attgtcagga ggtatggcac agagagtaag tatagctaga
     2281 gctctttctt tcaatccaga tatgttgttt atggacgagc ctttttcggc attagattat
     2341 tttacaagga ttgatatgca aaatgaagtt ataagaatac ataagtcaac taataaaggc
     2401 gtaatatttg taactcatga tattgatgaa gcattaaaga taggcaagaa aatagttgtt
     2461 tttacagatg aaagaaaaat aaaagaattt aatatagaag atgattataa tagagattta
     2521 acttcagagt actatattaa attaaaaaaa gatattttaa tgacaatgaa atcaaataaa
     2581 ggcatttaaa gaaattaata atattttaag gagtagagta aatgaaatta aaaaagctat
     2641 tgataggtat aacaatatta acgcttgcaa cagcatcttt agctggatgt gctaaaaaaa
     2701 ataatggaga aaaactttca gaaataaatt taacttatgt aaaatcacca ttaaatgttc
     2761 cttctataat tcaaaaacag gatgatttat ttggaaagga atttaaaaag gataatataa
     2821 aagttaactt ccacgaaatt actacaggtc cagagcaaac acaagcttta gctgctggag
     2881 aaatagactt tttacatgca ctaggtggta cgtcagcttt aatagctgca tctaatggag
     2941 tagagttaaa gatattaaac acttatagca ggtcaccaaa aggatttatg attttgacta
     3001 ataataattc aataaaatca gcagcagatt tagtaggtaa gaaggtggca gggccaaaag
     3061 ggactatatt acatcaggta ttgatttcag cacttgataa agaaggatta agtatggatg
     3121 atgtggaatt tgttaatatg ggtattccag aggcatcagc agctctttct gatgggagta
     3181 tagatgctgc attgattgct ggtccagcag ctcttaaagc tatgaagtca gggagtaaac
     3241 ttgtagcaaa tggtgaaggt ttagtagatg gcataatagt aactgctgtt agcacagact
     3301 ttgcagagaa acatccagaa atagttgaaa gatttatgaa ggttgaaaag gaaactttag
     3361 aatatgtaaa taataatttt gatgaagcta tggaaaaagt agctaaagaa gttgatttaa
     3421 gtcttgaaga aactaaagaa ttatatgttt ggtatgattt tagtttagat ataacagata
     3481 aagacatatc ttcacttgaa gatacacaag acttcttaat aaaaaataag ttacaagaga
     3541 aaaaagtgaa cataaaagaa ttaatatata atgctaagta gaaactatgc taaaataata
     3601 ctaagtaaga aatataataa aagtttaagt taccttatta aggtaacttt ttctattttg
     3661 aattagtaat ttaaatttat tttagaatga ttaattgata atagtgatta attaatcata
     3721 aaaagatacc tttttataga gttttgttaa gatgtctaat aatatagttg tatctatgaa
     3781 gtcagtaatt gtgaagttag taatatgatt aaatttatat attgtaaaaa tatcataata
     3841 tattaaaatt gagctgttat atgatgagta aaaaggtata ttaggaggaa ttatatgagt
     3901 tataaagtat atattgtgga agatgatata tcaataagta cattacttaa agattatatt
     3961 gagaaatatg gatttgaagt gattgttgaa gaaaactttg atgatataat gattacattt
     4021 gaaagcttta agccacactt agttctgtta gatgtaaact tacctaaatt tgatggtttc
     4081 tactggtgta ggtgtattag gcaacagtcg aatttgccta taatttttat atcagctaga
     4141 gatggtaatg tagaccaaat tagagcttta gaaagtggag cagatgatta tataacgaag
     4201 cctttttact atgatgtagt aatggcaaag ataaagagta atataagaag ggtatatggt
     4261 gaatattcaa ctaaaataga tgaaagaata gtggagttag atggattaaa gttttatcca
     4321 gaaaggttgg aactagaatt acatagtaag aatctaatta taaccaaaaa agaaggtata
     4381 ttgattgaat gtcttatcaa aagataccca aaggtagtaa gtagagatta tcttttagaa
     4441 aagatatggg atgatattga gtttgtagaa gaaaatactt taaatgtaaa tgttagtagg
     4501 ataaggaaaa gatttgagga attaggcata gataatgctg ttcagactat acgaggatta
     4561 ggatataaat taaataaaaa ttggtaagga gaaagtatga agttattttt aaaagattat
     4621 aaaggttata tttttatata ttatataggc atagttctga caattattta ctgtaatctt
     4681 atgaagttta ttagttttga tgagagttta tatattcttt tatttagttc ttttatattg
     4741 ttatgttttt taatatataa gtactataaa aatagagaag tatataatct gtttgaaaaa
     4801 ggaatacatt ctttggagga gtcagttttg tatttaggaa gctctttctt ggggagaaat
     4861 atatcagtta ttttaaaaca acaacataaa ttgtatcaat caatgataca agagcataaa
     4921 aagatacatg gtgagcattt aactttcatt aatcaatgga ttcatcagat gaaaacgcca
     4981 atatcagtta taagccttca gcttcaagat tatgagggag aagaagtaac tgaaaatata
     5041 agagaagaaa tagatagatt aaataaaggg ttagatatgg ccatgcattt tgcaagggca
     5101 gataattttc agaaagactt tatagttgaa aaagccaaat taaatgaaat tgtatctagt
     5161 attgtaaatg aagaaaaaag gttatttata aaaagtggaa tgattcctaa gattcaaata
     5221 gacaagttta cttatgttta tacagatgta aaatggatga aatttataat aggtcaatta
     5281 gttacaaatg gggtgaaata ttctaaagat tgtagcaact acataactat aaaatctgaa
     5341 gaaaataata agtatgtaat tttaagtata atagatgaag gaattggaat tgtttctaaa
     5401 gatttaaaaa gggtatttga cccatttttt acaggagaaa atggtcgtaa gtttggagaa
     5461 tctacaggta tgggtcttta tctagtaaaa aaggtatgtg atgatttagg tcataaagta
     5521 agtataaaat cagaagtagg aaaaggtaca gaagtttcaa tctcctttaa taaagatgta
     5581 aatagtttga taaagatgta aattatctgt tacaataggg tttttagtta attgtacttt
     5641 tttattaaat gaaatattca tagttaaata atccaaattt aaaagaattt atttgcaaac
     5701 cttacataga tgtaaggttt gtgtaatgtt tgcagatagt taaattttct aatctaaatt
     5761 acaattaata taagaaataa cataagggaa ataacataaa aaaagaaatt ttgtaaaaaa
     5821 ggaaggatat ttattgatga gtttagatgt tatttttata ttgaaatcag tcataatagc
     5881 tatagtagag gggcttacag aatttattcc agtttcatct acaggtcata tgattttggt
     5941 tggtaattta atagatttta aggggcaatt tgctgaaatg tttgaggttg taatacaact
     6001 tggagccata ttagcagtag tagtactcta ctggaaaaag ataaaagata gtgttagaga
     6061 atttttaaaa tttatattta ctggcggaaa agaaggaaag attggtttta gatttggaat
     6121 gaatgtaatt ataggttgta taccatttgc gattatagga gttctatttt acgataatat
     6181 aaaatcattg tttaatttac aatctgtaat tataggattt atagtgggtg ggattttatt
     6241 attagtagta gaaactttgt ttagaaaaaa gaatcattcc acagataata tagataaaat
     6301 tactccaata caagctttaa aggttgggac attacaagtt ttgtctgcat ggcctggtat
     6361 gtcaagaagt gcatctacta ttatgggtgg atggatagca gggcttaatt ctcctacagc
     6421 agcagaattt tctttctttt tagctgtacc agctatggtg gcatcttcag gaaaagattt
     6481 atttgaattt gattattcag taatgacacc aacattgtgg attgctttgg tagttggatt
     6541 tatagtagct tttattgtat caataatagt tatggaaaaa ttcgtgaatt ttttaaagaa
     6601 aaaaccaatg agagtgtttg ctatatacag aataatcatg ggtgcagtac ttgcagtatt
     6661 agctttgact aacataatta gtatatagaa aaaatagatt tattatctat agaaattaaa
     6721 ctaagagaaa ttataattaa caattatata tatgttattt caaaaattaa attaggaagg
     6781 tatgttattt caaaaattaa attaggaagg atagttaaat aatgaaaatt ttaactgtaa
     6841 ataatttaag taaagtatat ggtaaaaaaa taattttcaa tgcattaaat gacataaatt
     6901 ttagtataga agatggagaa tttgtaggaa ttatggggcc atctggcagt ggaaaaacta
     6961 ctcttttaaa tatgatttct actattgaca agccaactac aggaactatg gagctaaagg
     7021 acaagaatct tttattgtta aaaggtgaag aacttgcatt atttagaaga agagaattag
     7081 gttttgtatt tcaggatttt aatttattgg atacattaac tataggagag aatatagtat
     7141 tgccattgac attagataag gtcagtgtaa aagagcaaga taggagattg aatgaagtat
     7201 ctgaaatttt aggaataaaa gatttattgg gaaaaagaac ttttgaagtt tcaggtggtc
     7261 aagcccagag aactgccatt gctagagcat taattaatag accatctata cttttagcag
     7321 atgaaccaac aggtaattta gattcaaagt cgtcaaagac tgtaatggag ctatttcaaa
     7381 agataaataa agaaaataaa gttactacta tgatggtaac tcatgaccca ttagcagcaa
     7441 gttattgtag tagaatttta ttcataaaag atggagctat atacaatgaa atatataagg
     7501 ggagtagtag agagcagttt tatcaagata taatggatgt acttacatta ttgggaggag
     7561 ataattaatg aacataaaac agtttgctat taataatatt tcaagaaata tcaaagcgta
     7621 tttaggatat ttagcaagta ttactatatc atcttctcta ctattttctt ttgttatgtt
     7681 tacgagtcat ccagatttag atttatctca atttcctgat tatttaaaag aaggtctcaa
     7741 gatgagtaag ataattgcat atttattttt attcttcttt gtattttatt cagttagtgt
     7801 atttcttaaa agtaggtata aagaatttgg tatactttat attacaggta tatcaaaccg
     7861 acaagtaatg aaattaatct ttatagaaaa tatgataata aatatagtat cttctgtaat
     7921 tggaataata ataggcttaa tctttgcaaa gatattttta gtggtgatgt ctaccttttt
     7981 agaattatca ccattaaaat tctatatacc atttaatgcg atattgtcta ctttaatcta
     8041 ttttatgatt ttagctgtat taacatcact atttacttct tttatagtta aagaaaatca
     8101 ggtgttgaag ttacttaaag gtacaaaaac tccaaaacca gagcctaaaa catcactaat
     8161 gcttgctata ttaagtattt gtttgtttat aatagcgtat tataatgctg ttacatcaac
     8221 tgaccaatat acaacatacc tgcgcttagt tccagttaca tctcttacta tagcagctac
     8281 ctacttattt ttttctcaat ttagtgtgtt ttttataaag aaactaaaat taaacaagag
     8341 attttataga aaaaatacaa atatgctttg gatttcaaat ttaatttata aggtaaagga
     8401 taatgctaga atatttttct tgataactat aacctctgca gtagcattta ctgctatagg
     8461 tacagtttat tcattttgga aagatgtaaa gcgtcaaatt aatttaatat atcctaatac
     8521 aatatattat tcaacaatga ccttgcataa tgaccctaaa aagcctgata gcaaagaaaa
     8581 agacaaggaa agaatgagat ttatagaaaa taatctaaaa aaagaggata tagactatac
     8641 aagaattaat ggcgagttta aaactgtatt tcccaagaaa agtgatttta atgtcagaat
     8701 tatgaaagaa tctaagtact tagaaataac agaagttata ggggttaagc ctataagttt
     8761 tgaagataat gaatctatat cattattatc atcaagttta ccaggaaata agaaaataaa
     8821 agaaaatgtt actgtaggaa atagaagctt aaaggtggca aaacaagtag aagaatgtgt
     8881 tatgccagca tattataaaa atatgtatgt ggtaaaggac aatttttatg atagtataga
     8941 atcaaaattt atagtggata gatttactgc atttgaagta gaggattcaa gtaaaactat
     9001 agagatatgc agagaatttg aaaataaatt tgataatgag tcgggaatgc aaccatattt
     9061 gtttttctct aaagaattaa tgatagaaac tggtaaatta atgtattcta catttatatt
     9121 tttagcaata tttataggtt taattttctt cgttactaca agtagcttct tatacaacaa
     9181 gttttatatg gattgccaag ttgacaagaa aaagtatgaa cagttaaata aattagggat
     9241 gacatataat gagattaaaa aagcttcaac tattgagatt ggcatagtat ttttgttgcc
     9301 ttatgtagtg gctgttatac attcgatatt tgcacttact gctctgaaaa attcttttga
     9361 tttagaagta gcatcatcag ctgttttggt aatgggaagc ttgttcttgg ttcaaatagt
     9421 ttatttttta attgtaagaa ataattattt gaaagagata aaattaaatt tagttaatta
     9481 ttagttacta ttattaaatg ataacaaaaa gggtttaaaa ttaattaata ttactggaat
     9541 tatagatgtt tattttttca gtaatatttt ttattgtatt aactattaaa attttgaaca
     9601 aatataaagt ataatatgat aaatgtcaaa attataaaaa agttctactt atataaaata
     9661 taaagaggtt atatgtacat atgtgtagaa ataaataata aaaatatcga ttaatgttat
     9721 tagggggtgt tactcattag taaattagct aatacactta gaatgatgat attaattcaa
     9781 agtagaggca aaatgaaatg taaagagttg gcagaagagt tagaagtaag tgaaaggcaa
     9841 ataaaaagct ataaaatgta cttagagcaa gctggtatat ttataaattc aacgcctggg
     9901 atttatggtg gttatgaaat agataaatgt aacagcatct cattaattaa attattagat
     9961 agtgaagttt caattctaga tatgataaat tcacagttag agtacaataa tgatatttac
    10021 aaaactgaat ttaatagtat tgtagaaaaa ataaaagcag tattaaatac aagagtaaaa
    10081 agcgatacat atatggatta tttcacaata caaccacaac gtaattgtga ttataagttt
    10141 gagaaaaata agtgtaatga aataattaga gcatatacaa caaagcgtaa actttggata
    10201 gagtattatt cattgaactc aggcaatagt gagagaattg ttcatccata tggtttgttt
    10261 aattataagt cagatactta tatggtggct ttttgtgaaa aaagatttaa gtttatagac
    10321 tttaaattat gtagaattaa aaattataag gttttagaag aaaagtataa tgtagacaaa
    10381 agttttagtt gggatgaata tagtaaaaat agtataggaa tttataaggg agaagaaatt
    10441 aatgttgtta taaaaattag tcatccattt tcaacaatta taaaggagaa agtttgggtt
    10501 aataatcaac aaatcataga atatgatgat aaatctataa tgtttaaagc taaaatgaga
    10561 ggttatgagg agataaaaag ttggatttta agtatgggag cttatgttga ggttgtagat
    10621 ccagatagcc ttagaaacga tatattatca gagattgaaa aaatgaaaaa aatttactga
    10681 ttttttcaaa taatttatac ttggaccaat atacttcacg gtctagtgtt aatatattaa
    10741 ttaagagagg tgatattatg aaaatgaaaa ttgaatttag tacaagttgt ataccaatat
    10801 cttataattc gctctttatg agtattataa aagaagcaat aaaaaaatct aatgaagatt
    10861 actataaaaa catgtactat tataaagaaa agaataataa aaaaactaaa aattttacat
    10921 tttcggttta tgtaaaaaag tatagtattg aaggcgacaa ttttattata gaagataaag
    10981 taatattaaa tataagtact ccagatttag aattgggttt tcatatatat aatgggttaa
    11041 tgacttctaa aaaatgctta tataaagact atgaacttac aagaattaga atcgatttat
    11101 caagagaaaa gaaggtaaca gaagaaaggg tactatttaa tgcattgtct ccaatctgtg
    11161 taaagtctaa agaaggaaaa ttcttggaga taactgatga tagatacata gaagaactaa
    11221 actatataac taatgaagtg gttaaaaatt ataggggtag tggattaaaa agaaagttag
    11281 aatttgaaaa tatagatctc aaaaaggtag tagttaaaga gagtttaaga gaatttaaaa
    11341 aaataacagg taaagagtat caatatatta atggttataa aggtaaattt atattgaaag
    11401 gtgatattga tgatttaaat attatctaca atctaggact tggctttagg cgtgctcagg
    11461 gatttggaga tgtagatatt ttagaatgga ggtgagataa atgaagttaa gagtttatag
    11521 aggagattgg ttttttaata tgggtatagt tggattttta aatataataa agaaatcaaa
    11581 taaacaagca gaaatattta ttatggaaga ttatatcgaa tttgatagtt catttcttga
    11641 aaattttcat gaatattatt ttaattactt tatggatgaa tatgatgtat caaaaaggat
    11701 taaaaaaagt attgattaca gtataaattt tattaaatcc aaacctgata aagtcaaaga
    11761 tggaattaaa aaaattaaag acaccgtaaa acaacaaaat gataaggtta aaaaatttga
    11821 tgaagaaaaa tttaacttga taaaagagaa gttagatagc atttctaaga taaaaagtta
    11881 tgatgaattt gatagtttag aaattttagt ggatgagact atagatatat ttaaaataaa
    11941 atcaataaat gacaggctta cagcaaatct ttataaatat gtagttcaag ataattattt
    12001 tggacaagtt agttttttta atgttgctaa ggctaagtta gatttggatg gattaaaaca
    12061 ggtaatgttt aatgattatt taagacaaat tatatatttt ggagagttag aagatttatt
    12121 agaagagaat gactatgaca agttgaaaaa ctatttgaat gatagattaa atagtatagc
    12181 taaggatata agtgaaaaaa aagttagtaa gtctagtgta aatactatag aaaaaattat
    12241 gaaggaaata aataaaaact ttataaagaa aaataaaagc atagaaaata taaaagagta
    12301 tatggatagt ttagaaatat gtgaaatgtg tggtttatat aaaggaatat tagatgaata
    12361 ctcagaaagt aattttgctc cacttggagt aagtaccaat aatgctagga atatgttttg
    12421 gaagcaggag tatgtatcat caatatgtga tgtttgtaag ttaatattgt tctgtactcc
    12481 agcaggggct acttatacaa gaaaggatta tttgactaat gaagaaaatg agttttattt
    12541 atttgttaac atggatactt ctataaatga gctttttgat agaaacaata gcttgaaagc
    12601 tcaaaaaagt gagtcttcaa attctaaaga tgaaaatcct tttaatcaac ttataaaaag
    12661 tatagtagaa gaaaataaat taaaaagtga atggcaactt cgtaatatac tttttgttga
    12721 atttaaagca agtatagatt ctaaaaaatg taaaataaat tattttaata ttccaactta
    12781 tttagcaaag ttttttgtaa aagaaaataa aaaaatacaa agtatatatg attataaact
    12841 taaatcaaat gtattagatt taattttaaa aagtaaagac ttaaaacatt taattaataa
    12901 cactttaagg aatatagtta agagtaattt agaaagtaat aataaatcaa acatatcagg
    12961 gttatcttgt ttcaatgttg ttcaattaag aacaatatta aataactata agagaggagt
    13021 gtataaaatg gactataaaa agttgagaaa gatttatgag tcaggttgtg aaatacatga
    13081 ttattatatt gataagaatg ctaaaaataa aatagaagga ataacatata aaattttaaa
    13141 tttaattaag gttggtaata aaaatgattt tatgcaaaca attttaagga ttttttcacc
    13201 aagtgaaaaa acaccaccag aagaaatttt acagatattt gttgaagaag atttagattt
    13261 tgaatctgta gggtatgcat ttgtaacagg attaatttct ggaaaatatg aaggaaaaga
    13321 taaactatca aacgagaagg aggaaaaata agatgaaaag aggattaaca tttacagtaa
    13381 tagcacaagc tcaaagttta aactatggtg aagggatagg taatatatca gaattaaaaa
    13441 aattaagtag agctgatgga aatatatata catttgcatc tcgccagtgt ttaagatatg
    13501 acatagtacg attagcagca gaattgttta attggaattt acaggttgtc gataaagaaa
    13561 aaggtactat tcaatttaaa gataatataa gtataagaga atcagaagaa atggatttat
    13621 ttggatatat gaaaacaaat aaaaaagatg agaaagataa aaaaggaggt tctttgacta
    13681 gagaagctgc tgtaagatta agtaatgcga tttcccttga gccatataga agtgacatgg
    13741 actttttaaa taataaagga ttagcagata gaataggaga acatcctaat cttgctaaca
    13801 tagagcaaca tttaagttat tatacatata cagtgactat agatttatct aaaataggga
    13861 aggatggaga gatagaactt gataataaag agaaatgtag aagagtagta gaatttttag
    13921 aaataataaa agtattgaat agaaatatta gaggtagaca agaaaattta tctcctctat
    13981 ttgtagtagg tggagtatat gaaatagcaa atccattttt cttgggtaga attaaattaa
    14041 aaggagataa aaatggattt aaaataaata aacaagctat agaagaagta gtccaaggta
    14101 cttttttagg aaaatattta aaagaattta cctatgttgg aatggtagat ggggtattta
    14161 taaataaaga agaatttaag ggattgtttg aagataattt tttaagtgta gataaatttt
    14221 ttggacaact agttaaagaa gtaaaggaat attatggggt gaattaatat gaaggttttg
    14281 aaattagatt tatttcaaga aactgcatgc tataaaaaac catttgctat gaagattaca
    14341 gagacatatc cactgcctcc atattctaca ataaatggat taattcacaa aatattaaat
    14401 gctacagaat atataccatt taatataagt gtacagggaa catatgaaag tatatttaat
    14461 aattatcaga cgacatattt ttataaaaaa gatagtatta catctatgcc aatgaatagt
    14521 catatgctat tgaatgtaaa tttgataatt catataggtg gggattttga tttattgaaa
    14581 gaaatatatg atagtttatt aaattataac gagcatttat cattaggtag aaaagaagat
    14641 ttagtaagaa ttactgatat tagatttgta gaagttaata aatttgagat agatgaggac
    14701 atacaattag atgattatga aaattataag ttatcagaat gtgatataag aatgcctata
    14761 tatataccaa aaacaagttt acaagataaa gatatagatg gtataagtta caggctcaat
    14821 aattactatg ataataatgc tgtgggagat aaaaaaagag tttggaataa ggtggatagt
    14881 tattatgttg aggatggaaa tactatatca gttggagata tattattaga taatgaagga
    14941 gatttattat attttaataa tataaattag gagggagagt atgttatatg ctaaatctaa
    15001 tccagtggaa actttgagag aacatactga tgaactttta aaacaaatga atgtgttaag
    15061 agaaagttat ggaacaaata taaatagctt aaattttcta gaggaggaga tattttggca
    15121 attacttgac tttgttatag aatttcatga tattggaaaa gcattttcac catttcaaga
    15181 gttaataata agtagaatgg atactaaaat aaatgaacct aaaatagtaa ctcatctaga
    15241 aaataatgta ggtcataatt atctttctcc tgcatttatt gattatagtt atatagacaa
    15301 gaaaaaaaat aaagaactta gagcagtatt aaatcaagtt attgtatatc atcatgaaag
    15361 agatatcttt atagataaag attttaaaaa tttaatacaa aaaatattag atgaagattt
    15421 aataaataaa gtttatgaac tacagcatga atttaaagtt agatatccaa taaaaacaga
    15481 aaaattgagt aaagtatatt tacaaagtgt agaaaaaaga atagataaaa atcacaagta
    15541 ctataattta tatattatgt taaaaggaat actacatagg ctagaccata gtgcttctgc
    15601 tcatgaagtt gtggaatgca ataatgttat gaatatagga gaacacacag aaaattattt
    15661 aatgaaagaa tttggtagtt tgagagaaac tcaatcattt gcccaatcta atagaaataa
    15721 gaatataata ctgattgcat ctacaggaat gggaaaaaca gaaactgcct taatttggat
    15781 agataaagac aaggcatttt ttacacttcc attaagagta agtataaatg cattatttga
    15841 tagagcaaaa aatatagttg gagttggaga atcaaatgat acattcttag gattgttaca
    15901 ttcaacagca atagattatc tggaagaaag taatcaagaa aattcaagtg agattgtaga
    15961 tttagcaaag ttattatcct gtaagctgac attttctaca atagaccaaa tatttaaatt
    16021 tccttttttg tatagagggt atgaaaaagt gtactcaaca ttagcatatt caaaagtagt
    16081 aatagatgag atacaagcat attcaccaga aatagcagct gtattggtaa aaggtataga
    16141 aatgatacat aaaataggcg gaaaatttat gataatgaca gccactatgc caactatata
    16201 tatagatgaa ctaaaaaaaa gaggtgtagt tgacagtaac ttagctaact tgacatgtaa
    16261 cacagaaaaa ataagacatt gtgtgtctat tgtggaaaat tcaatagatg aaaatttaga
    16321 acaaataata caaagtggaa taaataaaaa agttcttgta atagtaaaca cagttaaaag
    16381 tgctatagaa aaatatgaat taatagaaga gataattaag tcaaaaggaa tagatattaa
    16441 tgtaaatctt ttacattcta tgtatataca agaagataga gcaaagctag aaaaatatat
    16501 aaaagaattt gcagatagtg atagtaatgg tatttggatt actacacaat tagtggaagc
    16561 atcccttgat attgattttg atgaacttca tacagaaaat tcaacacttg acagcttatt
    16621 tcaaagattt ggcagatgtt atagaagtcg tgagtatgaa gaaaatagtc caaatatatt
    16681 tatatataca gaaaaagcta caggaatagg tagtatttat gataaagata ttgtagaaaa
    16741 aggacttgag ctattgaaaa actgtatgaa tggaaaaaaa tgttttaaaa tgaaagaaaa
    16801 acataaagta caaatggtta agatactata ttctaaagaa agtttaaaag atacagattt
    16861 tgaaaaaaaa tttactcgtg ctttagatat attagatacg ataacaccat atagtttagg
    16921 ctctaacgag gcacaaaata tacttagaaa tattgaagga tatacagtaa taccggagga
    16981 tatatatagg aaaattgaaa aaactttaat aagagattat gaagagttgg gacaagaact
    17041 tacagaggca tatagcaatg atgatagaca attgataaat gaaataaagt ctaagagaaa
    17101 aaaagcaaga agagagataa ttaaaaaaac tgtaaattta ccaatatata aagctaaaca
    17161 aaatatagta gatatacagg tgaaaggtct ggaagattta aagatacttt tatataaata
    17221 tgatatacat gaagatgtgc atacaaaaca tatatttggc aaaggtgtga ttataggtaa
    17281 ggaaatagac caatttattt gatttttata ttaacaatgt ggctaaaatt tactaaagaa
    17341 ggtgagtttg tgccaataga tttagattta ttgaaagttc aaggtgtaaa gataaattat
    17401 tattatgtat gtaaaagaaa actatggcta ttttctaaag gaataactat ggaacaaaat
    17461 agtagtagag tattgtctgg gaagatagta catgaagatt catataaaag aatgaaaaat
    17521 aaagaaatgt tgattgatga tatcttgaag ctagatataa taaaggacga gtatgtaaaa
    17581 gaagtaaaaa taagttcaaa gatgaaagaa gcagatgaaa tgcagttata ctattactta
    17641 tactatttaa agaatagtat gggtatagag aaaaaaggaa ctataaatta tgttaaggaa
    17701 aagaaacaag aagaattgat attgacagaa gaaaaagaaa ggattattga aaacacactt
    17761 ataaatataa atgaaataaa catgaaatta tctcctccaa aaattgagaa aaaaccttat
    17821 tgtacaaaat gtgcttatta tgaattttgt tttgtgaagg aggagtaaca atgtataaag
    17881 actattatat tataagtaat ggtaatataa aaagaaaaga aaatacaatt tactattata
    17941 atttagaagg tgataagaaa atattaccag tagagcaagt tgatgatatt catatatatg
    18001 gtgaagttga tttaaacaca aaacttataa attacataag tcaatatgga gttatgcttc
    18061 atttttataa ttactatgga tattattcag gtacatatta tccaaggaag aaaaatgtat
    18121 caggattcag tttagtatgt caatcagcct gctatttaga taaaaatgaa agattatact
    18181 tagcaaaatc ctttgtggaa agtgcatcat accatatttt aagaaatatg agatattaca
    18241 aagttgatga aagtttaatt gatgctataa aggatgaact aaatgatttg aatgatgtca
    18301 aagaaatatc tgaacttatg ggtaaagaag gtagaataag aaaaacatac tataaatcat
    18361 ttaatcaaat attaaaagat gactttgaat tttataaaag agaaaaaaga cctcccaaag
    18421 acccagtaaa tgctcttatg tcttttggaa atagcataat gtatactaat gttttaagtg
    18481 agatatataa gacacaactt gaccctacaa taagcttttt acatgaacca tcaacaaaga
    18541 gattttcttt aagtttagat attgcagaaa tttttaagcc aattataatt gacacaataa
    18601 tttttagcct gattaataat aaaagaatta ataagaatga ttttgaatat caagataaaa
    18661 tttgttattt aagtgaaaaa ggaaagaaga aatttttgca agaatttgaa aataagatgc
    18721 agacaaccat aaaacataga aatctaaata gaaaagtttc atatagaatg tttataagat
    18781 tagagtgtta caaattaatt aaacatttta taaatgatga aaggtacaaa gttttaaagg
    18841 tgtggtggta agtatgtttg ttattgttac ttatgatatt gttgaagcaa agtcgttaaa
    18901 tagaattaga aagatactta gaaaatattt gacttggacg caaaattctg tttttgaagg
    18961 caatattact gatggaaagt tacataaatg tatttctgaa atagaaaata ttattgataa
    19021 tagagaggat tcaatctata tttatgagat aaaaaatcct aattcaatta aaaagaaatg
    19081 ctatggtatt gataagtatt ctgatgaaat gtttatatag gtttgcagtg agcgacattt
    19141 atgctaaaat aggtgttaac agttggaata taagggattg aaggtgtatg ataactgtta
    19201 tcaattgcac tactgttcgc tcactgcaaa ttttgatgtt tttattgaat tataattgct
    19261 tgattgaagt attttcaatg tattcaatta cacctatttt ggggttttat attaactaag
    19321 tggtatgtaa agcaatatat tctagcagga gcagatttag gagctttaca agttttatat
    19381 taactaagtg gtatgtaaag attctttata cagagaaaca cgatactatt tacaggtttt
    19441 atattaacta agtggtatgt aaagatatct ttgtactctt gattttccag ctttgatata
    19501 gttttatatt aactaagtgg tatgtaaaga attgcataat attagagagt ttaataccat
    19561 caagtgtttt atattaacta agtggtatgt aaaggatggt aaaatgggag atactttctt
    19621 tggattaaca ggttttatat taactaagtg gtatgtaaag ttgcttatac ttacaacttt
    19681 ttctgctgta gcatgtttta tattaactaa gtggtatgta aagaaaactg tttctacttt
    19741 tttagtccca agtaattccg ttttatatta actaagtggt atgtaaagcg catttttgct
    19801 tttatattgc ttcttctatc ttctagtttt atattaacta agtggtatgt aaagtctaaa
    19861 atatcctcac aactcctgta attgtatttt ctgttttata ttaactaagt ggtatgtaaa
    19921 gtggtttact aagaaaataa cggattttta agagaaaagt tttatattaa ctaagtggta
    19981 tgtaaagttt gatgaaaaag aagaatataa gagggatgtg gcaagtttta tattaactaa
    20041 gtggtatgta aagtaactcc aaactccgta agtcttgcca tttctccaag ttttatatta
    20101 actaagtggt atgtaaagga gtatcaagag accagggaaa ggcaggtaaa gcaggtttta
    20161 tattaactaa gtggtatgta aagaatggta aaatgaaggc ataataaatt tcaatatagg
    20221 ttttatatta actaagtggt atgtaaagag agacagttta aaactaaatc agaagaaaag
    20281 tcttatagtt ttatattaac taagtggtat gtaaagttta aagcaccctt aaaatctggt
    20341 tgggcatgtt ctcgttttat attaactaag tggtatgtaa agttggtaga caacctggta
    20401 cttggcttaa gattgataag ttttatatta actaagtggt atgtaaagca tgtgatagag
    20461 ataatataca atatgataga gaaagtttta tattaactaa gtggtatgta aaggcataaa
    20521 ataccttcaa aaatagcttc tactgacagt tttatattaa ctaagtggta tgtaaagcga
    20581 aataatgttt tgttttcgat gggtatatat acgggtttta tattaactaa gtggtatgta
    20641 aagtagcttt tgcgactgga agatacgcag ataatttagt tttatattaa ctaagtggta
    20701 tgtaaagatt gtaagctctt taatttctaa attagctccg attgttttat attaactaag
    20761 tggtatgtaa agttaagtag agcaatgtat catggttatg tgaaaagtgt tttatattaa
    20821 ctaagtggta tgtaaagcta gtaaattttg ctaaaaggca ctattattgt agtgttttat
    20881 attaactaag tggtatgtaa agcagttgac acaatgagta aaagcgaagc agagcaagat
    20941 tttatattaa ctaagtggta tgtaaagtta tgttatagga gcaggttgca agaagtataa
    21001 gcaagtttta tattaactaa gtggtatgta aagcatagat tttggagatt taagggaagg
    21061 caatatgtgt gttttatatt aactaagtgg tatgtaaagg ggtttgcatc tttattagat
    21121 aattttatta atagagtttt atattaacta agtggtatgt aaagtaaata tagaataaag
    21181 cattttagtt tacaatgcaa gttttatatt aactaagtgg tatgtaaaga cctaaaaaat
    21241 caatgcagct tatcttatat gcaatggttt tatattaact aagtggtatg taaagattaa
    21301 ggaatagtaa ttacagtgga ctggagttag tgttttatat taactaagtg gtatgtaaag
    21361 acgtttcgca agggattttt taaagcgaat ggataagttt tatattaact aaatcatatc
    21421 taaataaaat acacttacct ataaacatga taaaatcaat acaaaaatga ggtgaaacaa
    21481 aatttatgat aaggaaatta aacaataaag atataaataa aatcatggaa atatgggaag
    21541 aaagcacaat caaagcacat ggctttataa gtaaagaata ctggcaaaat aaccataatg
    21601 ctgttaaaaa tgagtatata cctatatcag atacatttgt atatgatatt ggagatgaaa
    21661 taaaaggatt tataagcata atagataaaa gttttatagg agctttattt ataaagccca
    21721 aataccaaaa tctaggtatc ggaggtaaac ttttagatta tgcaactgaa aaatataaaa
    21781 gtctaagttt agcagtatac aaagataata aaaaagcagt tattttttat aataaaaaag
    21841 gttttaatgt agtaaaaggg caattaaatg aagactcagg atttaaagag tacataatgg
    21901 aatatagtaa ataatatgag tgtattctat taaaaagata attaatctat ttgatatttg
    21961 attagaggca tttttataag agtaattttt ttaatagatt atataaagat aaatatattt
    22021 gttatatatg taagttaatc agaattgcta tggttacaaa agaggaaaat aaaattgtat
    22081 ggtgtatttc aaatttaaca aatttaccat ttaaaaataa taagtttgat ataatattaa
    22141 atgtactttc acctgtaaac tataaaagat ttgaaagagt tttaaataat tatggaatgg
    22201 caagaaaggt ttgttaaaat ttaataatta ttagattata gaaagttgcc ataaaattag
    22261 ttcagtaaga actagtttca tggcaatttt aattcttatg agagtattta tttttacata
    22321 ttttaaaaac ttatacagta taataatgta atcttactat atcagtctat agatatttaa
    22381 atcttaaaat gttctctttg agataagttt atttcagagt cacaatttcc acaacagtaa
    22441 gatgttgaga catctttaaa tttctcagta ttctcatcaa agttcatttt tttctttgca
    22501 ataattccta ccttggttaa attagagcca caattattac agttttgaat tttgcatagg
    22561 ttagatagtt tatcaagtgt aacatcttct aataattcat cacaattaca acatctgata
    22621 gaagaaactt cattagatat ttcaataggt tcagcttctt tagaagaaaa tttatatgtt
    22681 atgtcatttg atactttata acctgtgtca aatatattag aattacaact tggacatagg
    22741 tactttggaa gatatatatc ttttttttca aaagtatcac tactagtatt atagtttaat
    22801 tcatctaaaa ttggtctttc atctaggtta ttatctttat ttaagtttag aagataatta
    22861 taaatttttt tatcttcatt ctgttttgat gtatccaaca agtgttccat tatattagtg
    22921 tattttttat tttttgaagg catgtttaaa tccagataat tgttttcaat agcaaagcac
    22981 actatattga aatagttata tttaactgca aaaaataata acatttcatc aaatacttta
    23041 tctattattt tgtcagaaat acttatccaa aaatctggtg actctaagta aactttccta
    23101 ctaagttcat ctaactcttc atctatatta ttttcattaa ctttcatatt atcacttcct
    23161 tttaaatatc ttgtgtataa actatttgtt actgtttttt atataaaata aaatcttata
    23221 taaaaatata tcatattata atttacaagt atagtctaaa tagagctgtt tttaagcaaa
    23281 gtcttataaa tgactattaa aacataaagt aacagtgtaa agtttactta taaattaaat
    23341 gtaaacctaa atacttataa gggttgacaa aaaaacgcct ttattttata ctaaaacaaa
    23401 gctttaatag aagctttgta tatgtacata taaactaaat tgaataagac atatgaaggg
    23461 aattataaaa atgaaaaata ctaaagtaaa tattcaagat ttaactaaaa tgtcaatatg
    23521 tgtagcatta ttgtgtatat catcttacat atatatacca ttgccattta ctccagcagg
    23581 agtaacagca caaacaataa tgataaattt gatagctttg attttaacac caagacaagc
    23641 atttagtaca gttggtgtat acataatgat aggtttaatt gggattccag tatttggtgg
    23701 aggtacatct ggtattggaa agttgttaag cccaacaggt ggtttttatt ttgggttttt
    23761 gtttgcagca ctaattatta gtttattaaa aggacgaaat aatgatatta agagatatat
    23821 actaataaca atttttgttg gaatgcctat tatatatttt atgggaacag tgtttatgtg
    23881 ctattttaat caaatgacag tagaagcagc actttttgca gcagtagtac catttttaat
    23941 tggagataca ataaagtcag ttattgcgtc ttttttaggt actaaactga acaatgtact
    24001 cagaaaaaat ctataatata aggaagggtg taatatatgg aggaggtttt tatattagga
    24061 ggattgagaa gtcatatagg tctaaaaaat ggaatttttc aatttgttca acctgaatta
    24121 ctaggagcaa gtgttttaaa acatttaatt aagaagtatg aaattgataa aattgatgag
    24181 attatatgtg gaaatgctgt tgggacagga gggaatatag ctagattaat gactttaaca
    24241 gcaggagtgt caaatgaagt gcctgctttt actgtggata tgcaatgtgc ttctgctatg
    24301 atgagtatag acatagcttt ttcaaagatt aaatctgggc agtgtgattt aatcattgca
    24361 ggtggttttg aaagtagttc tctacaacca atgcgtacat atcataagaa tgataagcga
    24421 tataatataa ataatccaaa ttatacagtt gctcaatttt ctcctgatga taatagccaa
    24481 aatagtatgc tagaaggggc agaaagagta gcagagttat atcaaattaa gaaagcagaa
    24541 ttggattttt gggtaaagga aagtcataaa agagcaaaag aagcaagaga agaaaaaata
    24601 tttgatgata ttatatttcc tataaataat agtacatgtg atgaaggtat acgtgataag
    24661 atgagtcaaa gattattaga tagaatgcca tctattttag gaaaagaaag tattacgaat
    24721 gcagcaaatt catgtcttat taatgatgga gcttcattta ttatactatg ttctaagaag
    24781 tatctagaac atgcaaaaaa taagcctata gcaaaaattg ttaatacatg tacaataggg
    24841 acagatgcaa atttaagccc aacatcagcg ataaaagcaa tggataaact tttagaaata
    24901 gaaagcctta gttatttaga tgtatctgct gttgaattta atgaagcatt tgcagttata
    24961 gatgtgctgt ttcaaagaaa gtatccagag ttaatagata gatataatat atttggtgga
    25021 gctttagcgt atggacatcc ttatggtgct tcaggtgcaa ttattgcatt acatctttta
    25081 aaagcattag aaaagactaa gggtagatat ggaatttgct ctatagctgc agctggtggt
    25141 ctaggttcag ctttaatgat tgagagggtt taaattatga actattatga acttttaaga
    25201 ataaaaagcg ataggcataa aaataaaaat tttttaatta tagatggaga aaaatatact
    25261 tatgaaaata tattgagtta tagtgaggaa ataggaaaac aaatttattt aggtgaaaat
    25321 attcctattt taatatattc taaaaatata atgtttcagt taattagttt ttttgctatt
    25381 aattattcaa aaaatattcc tattatttgt cattataatc tttctaaaaa agtattagat
    25441 gatattttac taaaaaataa tatttcaatc attatatctg atgaatctat ggacgttatt
    25501 gatttatatg atgataacaa taatgaagta gcaaaaaaag ttaatttgtc tatttttaat
    25561 cctaaattca atatatatat gtatcaatat aagaaactta taaattattt agataaaagc
    25621 atttgtatgg gagctttatc ttcaggttct acaagtgttc caaaagtatt atatagaacg
    25681 tatgagagtt gggctggatt ttttcctata caaaatgcta tttttaatat ctctggggaa
    25741 tcaatcttgt ttattaatgg aacacttagt tttacaggga atctaaattc tataatgtca
    25801 gtattatatg aaggaggtag tattgtaata agttcaggtc ttaattgtaa atcatggatt
    25861 aggacaataa aacaatataa tgtaactaac atatatctta tacctataaa acttcaactt
    25921 ttggttaaac acttaaaaga atcagtactc aaagttgtaa gtatttttac agggtctcaa
    25981 ttattatttg aagatactgc aagaaatcta aaaaaatata tgccaaagtc tgaaattatt
    26041 ttatactatg gggcaagtga attaaattat attacatatt tatgctatga tgaactaatt
    26101 gaaagacctc taagtgtagg cagaccattt ccaggaatag atgtatatat tagagaagaa
    26161 aaaatttttg tgaatacaga atatgcagta tataatgcaa ccaaacctta ttctgtcaat
    26221 gatattggat attttgataa tgatggatac ttaatatttg aaggaagaag tgatgacatt
    26281 gtaaatattg gaggatttaa agttagttct actaagattg aaaatgaagt taaaaaaatt
    26341 cctcaaattg aagatgcagt tgtattgccg tattcagaca ctataagagg aaatcaaatt
    26401 gtattatttg taataactat agacaaaatt acgaagaaag atttgttgat taaaatgaaa
    26461 gataatctaa tgaaaaatga aatcccaaag aaaattatct ttttaaattc atttccatat
    26521 acctcttctg aaaagataga tagattagca ttattaaaaa tgttataagt ataatattta
    26581 gtaattttag tgaaccaatg tattgataaa aacatattgt atatagtaaa ggaggcttac
    26641 aatatgtcaa atcaatacga tataactgtt attgggggag acctgcgaca agtgtacatg
    26701 gtaaaaaaac taattaataa agggtattct gtagtcactt atgggatatc aaatgaaatt
    26761 ataaatggaa tcgttggaaa atcaacttca ctagctgaag cactatccaa aagttccatt
    26821 attttatgtc cgattccatt tacaaagaat caagttaaca ttgaaaatac tgataattgt
    26881 cttgatgcta ctattgataa cttgctaatt aatttatctc ctaatcaaat cttatttgga
    26941 ggtaacatac caactaaagt ttgtaaattt tgcgagcaac actctattca gatttatgat
    27001 tttatgaaaa tgaatgatgt tgctatttta aatgcagttg ctacagcgga aggggctata
    27061 tcagaagcta ttaaaagaag cataatcaat atacatcaaa gtaactgctt agtattaggt
    27121 tatggaagat gtgcacaaat acttgcaaaa aaattatatg ctttggatgc aaatgtatgt
    27181 gttggtgcaa gaaataatga tgcaagaagt acggctagtg catttggata ttccagtatt
    27241 tctttaaatc aacttgatga aaaactttta caatttgatt atatttttaa cactatacca
    27301 gattgtattt tgactaaaga aagattagaa aaagtatcac aagaagtaac tattatagat
    27361 atagcttctt ctcccggagg agtagattat tctgctacta aagaagtagg gattaatgcg
    27421 actctttgtc ttgggcttcc tggtaaatat tcaccaaaga catctggtga aattcttgtt
    27481 aacgctatag aaaatattat aaatgaaaga agggattaga aatgagactt gaaggactta
    27541 caattggagt aggatttact ggttcgtttt gtacttatga taaaatattt atagagttag
    27601 agaatttggt taaagaagga gctaatgtcc acactatatt ttcagatgta tcacaaaata
    27661 tagattgtag atttggaaat tctgaagagt ttatgaaaaa agcatatgaa cttacaggaa
    27721 ataaacctat agttacgatt gaagatgcag agccatttgg acctaaggga attgctgata
    27781 ttataataat agctccttgt actggaaata ctgctgcaaa attagcaaat ggtattacag
    27841 attcaccagt attaatggca gcaaaaggtc atcttcgtaa tgataaacca ctagtaatat
    27901 caatatcaac gaatgatgct ctaagcttta atttcaaaaa tattggtatt ctccttaatt
    27961 ctaaaaatat atattttgta ccttttggtc aagataattg caaagcaaag cctaattcta
    28021 tgattgcaca tactgagcta ataattccaa ctatagaact tgccctagag aataaacagc
    28081 tacagcctgt tataaaaagt ccacatcaat agaattggtt ctataatatt atgtattaga
    28141 tgcaagacta gcaaagaggc tgtctcaaaa tagagataag cctctttttc attgttgaaa
    28201 tgatgaaaat atatttaatt tcatacaaaa aaatgcctta tggactaaaa agtctatttt
    28261 gagctaatct ccataatttt tggtatatta aaattgttta cttaatctaa tttttaaatt
    28321 agaatttata tcgctttgac tcttcaaata tcaatctaac tgttgttgat acaaaagaag
    28381 aggacataat taaaacaaat actgatagtc ctctaataaa caaattattt acataataag
    28441 ttactattcc aatacctcca atcgttaaaa ttacacttat aatcaaagaa aaaatgctaa
    28501 ttatttttaa ttttttcatg attatcctcc ttcttataaa tttcaaattt atctatataa
    28561 tattaaatat attttatttc atagtatata aaaatcatga atatatattt ttttaattat
    28621 actatatatt gtaacttttt gtatatttaa ctatatttac tttaacttgt taatcaagtt
    28681 attattttca ttttcaagta tttttatttt taaacttgat acagcaccat attaaaaatc
    28741 atttttataa agttttattt gtaaaaaata caaaaatata aacgttaaaa aaataacgtt
    28801 atccttaagt ttttagatga ttttattagt aatttacgta aaaaataaag tgacatctag
    28861 ttaaattaag tatttgtaaa gctagatatt attagtataa atgatgttat attagataaa
    28921 aaataaaatg ttaaaaaaat aacttgaaaa tagaaaaagt gaatgctata atgttaataa
    28981 attaacataa taaataaaaa actatctcag gaggttgtta aaatggctca taaagaacaa
    29041 gtaataatag aaaataaaaa agaaaatgaa gttatgtcag ttggtttaga tactgtaaat
    29101 aacgttgaaa gcttagttaa aaaactagca aaaatcaaag aagctcaaaa aatatttgct
    29161 acatatactc aagagcaagt agataaaatt tttttagcag catctttggc agctaataag
    29221 caaagagttc ctctagctat aatggcacaa aaagaaactg gtatgggaat tgctgaagat
    29281 aaggttataa agaatcatta tgcctcagag tatatatata atgcatataa agaaactaaa
    29341 acttgtggtg ttatagagaa agatgaagca tttggtatga ctaaaattgc tgagccaata
    29401 ggtgttattg cagcagttgt acctacaact aatccaactt ctactgctat ctttaaagca
    29461 cttttagctt taaaaactag aaatggaata attttctctc cacatccaag agcaaaaaat
    29521 tctactatag aggctgcaaa agtggttctt gaggctgctg ttttagctgg agctcctgaa
    29581 ggtataatag gatggataga tgagccatct ttagaattaa ctacaactgt tatgaaagag
    29641 gtggatttga ctcttgctac agggggtcct gggatggtta aatcagcata ttcatctgga
    29701 aaaccagcta ttggagttgg tgcaggtaat actccagcaa taattgatga aagtgcagat
    29761 ataaaaactg ctgtaaactc aattcttgta tctaagactt ttgacaatgg tatgatatgt
    29821 gcttctgaac aatcagttat agtattggaa aatatatata atgaagtcaa aaaagaattt
    29881 aaagagcgtg gtgcttattt attagataaa gatgaaacag aaaaaataag aaatataatt
    29941 ttagtaaatg gaggattaaa ttctaaaata gttgggcaaa cagcttgtac tatagcaaaa
    30001 cttgcaggat ttgaagtccc agtagatact aaggttttaa taggtgaagt agaatcggtt
    30061 gaaatagaag aggcttttgc tcatgagaaa ctttcaccag tgcttgcaat gtacaaggca
    30121 agtgattttg atgatgcagt tagaaaagca gaaaaattag tagaagatgg tggatttggg
    30181 catacatctt cattatatat tgatgatgta aatcaaagag aaaaacttga taagtttact
    30241 tcagctatga aaacttgtag aattttaatt aatactcctt cttctcaagg tggtataggg
    30301 gatttatata attttaaact agctccttct cttactttag gatgtgggtc ttggggtgga
    30361 aattcagtat ctgaaaatgt aggagttaag catttactta atattaagac agtagctgag
    30421 aggagagaaa atatgctttg gtttagagca ccagaaaaag tttatttcaa gaaaggttgt
    30481 ttaggagtag cattaaaaga acttaaagat gtaatggata agaagagagc ttttattgta
    30541 acagatacat tcctttacaa taatggatat actaaagcag ttactgactt attagatgaa
    30601 atgaatatta agcacactac attctttgaa gtagaaccag acccaacttt ggaatgtgct
    30661 aagataggtg ctaaagctat gagagaattt aatccagatg taataatatc tataggtgga
    30721 ggaagtgcaa tggatgcagg aaagataatg tggacattgt atgagcatcc agatgtagat
    30781 ttccaagatt tagctatgag atttatggat ataagaaaaa gagtatatac attccctaaa
    30841 atgggtgaaa aagctaactt tgtagctata ccaacatcag caggtactgg ttcagaagta
    30901 acaccatttg ctgttataac tgaccaagat acaggggtaa aatatccatt agctgattat
    30961 gaattgatgc caaatatggc tatagttgat tctgatatga tgatgaatat gccaaaaagc
    31021 ttaacatctg cttctggtat agatgcctta actcatgcat tagaagcata tgtatctatg
    31081 cttgcaaccg attatacaaa tggattagct ttacaagcca ttaagagtat atttgaatat
    31141 cttccacgtg catatgacaa tggtgcaaaa gacccagaag ctagagaaaa aatggcaaat
    31201 gcttctacaa tggcaggtat ggcttttgca aatgcatttt tgggtgtttg tcactctatg
    31261 gctcataaat taggtgcttt ccaccatgta ccacatggtg ttgcaaatgc tcttttgata
    31321 acagaggtta tgaaatttaa ttcttcagac gcaccaaaga aaatgggagc attctctcaa
    31381 tataaatatc cagaagcatt aaagagatat gctgaagtag cttcattctt aggattaaaa
    31441 ggaaattctg aggaagagaa attccaaagt ttattgtcag ctattgaaga tttaaaattt
    31501 aaagttggta ttcctaaaac tataaaagaa tttggagttg aagaatctaa gtttatggac
    31561 tcaatagatg aaatggtaat tcaagcattt gatgaccaat gtacaggagc aaatccaaga
    31621 tatccactta tgaatgaaat aaaagatatg tatttaaatt catattatgg aagataaatt
    31681 tactataaaa taggaaaaat aaaaattctt atacataaaa caaagtttta ttgtataaga
    31741 attttttttg attggaaaaa tgtatagttt ttattcttta atttaaaatt caattaaata
    31801 gtgttattat aataataaaa gaatgttttt atggttatta ggttgatttt atgtgtaaca
    31861 tttaagaata gttattacaa tataaatgat gaattggtat aaaaaggata tattatctat
    31921 atgaagtatt gactaattat gggaggagtc gaatgacaag aagaagtaag agttttacat
    31981 taattataat tctttttttg acatcattat ttttgacaat gggatatatt tatatagaag
    32041 atacaaaaaa tcttcttatg tcagaagcaa aaatacatat aaaagaagtt gcaatacaag
    32101 gctctcaact agcacaaaga cagattgaaa aagatttaga tgttttaaat attttttcta
    32161 actattatgc ttcaaatcca gacataccta atgaggaaaa aatgaagaat cttttggatg
    32221 agttggaaaa tcaaaaattt tacactatgg caatagttga tataaatggt aatgctgaaa
    32281 ataccaaagg tgataagttt tcagtgaaag atagagaatt tttcaaaaac tcaattaaag
    32341 gtaaaaagta tgtttcaagt ccatatgctg atgaagtaaa taagtctata aagaagatta
    32401 ctatttcagt gccattatta aataatgata aagtagttgg agttttatat tgtacctaca
    32461 atatcaatac tttgatgaaa cttattaatg tatcttttta tgaaaataat agtatatctt
    32521 atgttgtaaa aaatgatggt acagttattc ttcatccaca agaggatagc atatcaaaaa
    32581 atatttataa attgttaaaa caggataatg atattcgaga agtaaatagc ttaaaaaaag
    32641 aactgcaaga aaacaaaaca ggtgcaactg tattaaagat gttggaagaa agaagatatt
    32701 taggatatgc tactatggat aatgggaata gtgaaaataa ctatataaaa gattggaatt
    32761 tgattttttc aattccagaa actgttgtgt ttagtaattc agaaaaaata atcaacagag
    32821 ctatatatgc agtgttattt attatattaa tatttattgc aattattttt tatataattt
    32881 atataaaaaa atctaatgaa aaagaaatat taagtttggc ttatgaagat aaagttaccc
    32941 atataggaaa tcaaaataaa ttttatagag agtgtagtaa gtatctttta gataaaccat
    33001 ctttaaatta tattatagta tattttgata ttaataactt taagatgatt aatgatactt
    33061 ttggatatga atttggtgac aacttattaa ttacgatagc aaaagcttta aaagaagaac
    33121 tgacagaagg ggaagtattt gcacgacttt caagtgatta ttttgcaatt ttctgtgatt
    33181 ataaaaatgg aagaaataaa attataagaa aacttgatag tatacgaaat aatattgaaa
    33241 gtaatttgag tatagtcttt gaaatttctc tgtgtgtggg tatttatttt gttgaagaag
    33301 atgaagtaga tattcaaaag gctgtaaata aagcaaatat ggctaggtct gttgctaaag
    33361 gtaaaaatat aaattatgct atttataatg aagatgttag gaataagctt agtgaagaat
    33421 caatgatttt agatgatata aaaatagcat tggtaaaaaa tcaatttgaa gtgtattatc
    33481 aacctaagtt ttcacttgta aatggagaaa tgatagggag tgaagcacta ataagatgga
    33541 atcatccaga acatggtttt ataagtcccg cagtatttat tccaatagca gagaaaagta
    33601 agttgatttt aaaaattggg agatttgtat ttgaaaaggt ttgcactgat ttatctgaat
    33661 ggaaaaaaca aggtaaaaag atagttccag tttcagtaaa tttatctaga gttgaattgt
    33721 atcaaccaga tattgtaaaa tttatcaata aaacaataca aatgtataat ctaagttcag
    33781 atttaattga aatagagata acagaaactg tggctattaa tgagttaaat attttaaaga
    33841 atgttttaaa tgagttgagg aagtatggat tttctatttc tatggatgac tttggtacag
    33901 gatattcttc tattagttgt ttaagagata tgccaattga tatattgaaa ctggataagt
    33961 cttttcttga tggtattgaa catgatgaga gaagtcgcaa tatagcaaaa tcaatagtgt
    34021 ctctagcaaa atcactagat ttagttgtaa ttatagaagg tgttgagagt aaagaacaag
    34081 ctgagttaat gaaacaattt ggatgtgatt tagttcaagg attttatttt gcaagaccaa
    34141 tgccagctaa gaatttttta gatttacttt gaaataaaat ttgattttta tataaagcac
    34201 tattatgaat gcttgatttt aataaatcac tgctaaataa ttagtgtttt tttattttat
    34261 caatgtatta tctaatataa ggtaaaaaat aattgtattt tataaaaatt atattaaaaa
    34321 taaatttatt ttgctaataa acatgtcatt aacaaaagaa tagtactata atgtatagat
    34381 gataaaaact ttaataaaaa tttagtgtat aggagttgtt taagtatgat agatgtaagt
    34441 attgataaaa aacttaagga aagatggcct aatgctaagc tgggttgtat tcaagcaaaa
    34501 gtagcagtaa ataaaagctc agaaaaatta attaatgaaa taaatgagtt ttgtgatact
    34561 ctaaataaaa atctaaaagt tgaagacatt acaaaactag ataaaattaa agatgccaga
    34621 aatgcatata aagaacttgg aaaaaatcca agtagatata gaacgtcttc agaagccttg
    34681 gttagaagaa ttattcaagg taagggtctt tacacaataa acaatatagt agaaataaac
    34741 aatttaatat caataaaatc attatatcca gtaggtacat ataatgtaag taaattacat
    34801 tcaccagtat gttttactgt aggagatgaa ggagaacagt ataagggtat tgggaaagaa
    34861 ttaataaata tagaaaatct tcctatattg tctgattcag tgggtaaatt tgggagtcca
    34921 actagtgatt ctgaaagagc aatgataaca gaagatgcga atgaaatatt aatttgtata
    34981 ttttctttta gtgaagaatc tgatattgaa gaatattttg gatatgctaa ggaattactt
    35041 aaagaatacg ctgatggaaa agatatagaa actaaaataa ttaaatagaa tccatataac
    35101 aacgttatgt taagctaaaa ttcaatataa aaataagtta tgataaagaa actaacacaa
    35161 aattagtttc ttttttgaaa gagtagttta gtgttacaaa aatagataga tatccccacg
    35221 agtattaaaa gtatggtaat atattaatat agaagggatt gtatttaagg gattttgaaa
    35281 ggagtgattt ataataactg ttttttctaa aagataaaat ggttttatgg aaataactat
    35341 atatttaaaa atataaataa taatacagtg atttgggtat ataaaataag acatacatgg
    35401 ttttgtttaa aaccaataaa gtacataggt aattacaatg taaggaagga tttaattatg
    35461 attgatggaa aagaggtaaa acaagaaagt ggacaaaaaa atctaaaatt taagatagct
    35521 atagtagtag gtattttatt tgtagcttat ataggaatgg caatcttttt tagaaatcat
    35581 ttttactttg gaacgactat taatggtgta agggcttcag gaaaaacagt tgaacaagta
    35641 aatgatttgt taacatctag tactaattcc tatactttaa acttagatga aagaaacaat
    35701 aagaaagaac aaataaaagc aaaagatatt gatttaaagt ttacaccaga tgataaagtt
    35761 caaaagataa aagatagtca gagtgctatt ggatggattg gtgggatatt taagtctaaa
    35821 gagtataaca atatggtaac tctttcatat aataaagatt tactagaaaa aagatttaac
    35881 gctctatctt gccttgatag taaaaatgtt gtagagccta agagtgctta tcctaagtat
    35941 gatagtacta aaaatgctta tgttatagtg ccagaggtac ttggaaacaa agtgaaaaaa
    36001 gatgattttt ataagttagt acaaaactca attaattctg gtaatacttc tatttcttta
    36061 gatgaaagta aagtgtatga agtgccaaat aacacaaagg attcagaaaa gttgaaacaa
    36121 gctattaaga cactagataa gtatgttggt gtagttgtta catatgattt tagtgaccgt
    36181 aaggaaactt tagatggttc tgagattaat aaatggttaa aggtagactc agaaaagaat
    36241 tatgatataa ctttcgataa tgatgctatg gtagagtata caagaggttt aagtaaaaaa
    36301 tatagtactt ttggagattc aagaccattt aaaactgcaa caggtaaaaa tattacaatt
    36361 tcaggtggaa tttatggatg gttgatagac aaaaagaaag aagctgaagc attagttgat
    36421 gttgtaaaag ctggtaaaaa tgttacaaga gaacctattt acatacaaaa agctgtatct
    36481 cgtaatagag atgatattgg aaatacatat gtagagatta gtctttctaa ccaacatatg
    36541 tggttcttta aaaatggaga aatgcttgta tcaacagaca ttgtaactgg taatttagct
    36601 agaggatttg ctacaccatc aggtatatat cctcttaatt ataaggctag aaatgtttca
    36661 ttaactggtc aaggttacag ttcccctgta agttattggc ttccatttaa tggaaatata
    36721 ggtattcatg atgctacttg gagaaattct tttggtggag gaatatataa gtcttcaggt
    36781 tcacatggat gtgtaaatac acctttttct aaggcaaaga aaatatatga aaatatagaa
    36841 ccaggtacac caattatttt atactagtaa atgtgttact aacagttaag cgaagtcatc
    36901 ttagtttatt tagggtggct tcctttttat ataaagttta ttgaagttta cataaagact
    36961 atttaaaagg agaaatacat aatgaatgaa aaattaacta agattttaga gaaagctaag
    37021 aatgatgatg aatttagaaa agaacttata aaatcaagag aacaacgtga tgttatggat
    37081 tcattttgta aggttgttac atctagaggt tatgatataa cagtagggga acttttttcc
    37141 ataggagaag aatatacatc aaatctactt aaaagtgtga atggaggggc aacatatcct
    37201 attgaagatt ggagtgattg gtacgaggat ttttttataa tgttgtcgaa tatatagagt
    37261 aactaatgtt attatctact taagattaac accttaattt taaaaaaaac tattagagct
    37321 aagtgtaaat tttatcaatc tttaaaaata ttgatttatt tctagctata tataaaaaaa
    37381 ttagattaaa aataaggtga caaaaatcga tataccttga tgatttataa aagttagaca
    37441 aaatagtgct agatatttct aaaaattcaa aaaaaacaat aaacttcaag agctagaggt
    37501 tgaaaaataa aataaaaaac ttttatatgt aataaattaa attgaaatta taaaaaaaat
    37561 aaaaaagaaa ttttaaatgt cgacatagcg ttaattttaa gacaaaataa cgctattgac
    37621 aaactatatc gctttaaatt ataattattg aaaataatgg tatttaaaaa tcatactcat
    37681 gcaatagtct aaaagtaagt caaaaaaaaa tgtaaatcta ggcaagtact attctaaaat
    37741 atgttttatt aagaaataaa cgttgaaaaa tattaattat tatataaaaa tgctgtttat
    37801 actttaacaa tgaggtagta atctaattag aataaaaaaa tctaattggt tatatacata
    37861 gtaaaaaggt aagagaggtg atttggatgg cttttgaaat aataaaaagc attgttgagg
    37921 cagagcagac agcagacagt atcaaagtaa aagctgttac tgatgcagag tctatcagag
    37981 ctgatgctgt aaacaaatgt gaaagcatat ttgctgatgt aaaaaaacaa gcaaagctta
    38041 tggaagaaac tcttattgag aaggcagtca ccgacagtag agcagaggtt gataaaatct
    38101 tagctaatgc taaaagtgaa tgtctgaaaa ttgaaaaaac tgctaaagaa agaaaaagta
    38161 aggctattga agcggttatt ggaaaggtag tgagataata tggcaatagt taatatgaac
    38221 aaaatatcta ttgttggctt agaagctcaa aaaagccaga ttttaaagct acttatgaac
    38281 cgtgggtttg ttcagattga tgatagtgcc tttcttactg aggaggagga attaaaaaat
    38341 tatcttgtaa aagatagtga agaatctgaa gttataatgc tagagcagaa gatgtctcat
    38401 gtaaaccaag caattaatat tgtttcttca ctagtgaaac aaaaaaaatc cctacttgca
    38461 ccaaaaagag agtttaacaa aattgatagt gaaaaagaag agcaagttta tgctgaagct
    38521 cttgagttaa acaatttaca caaggagata ggtacaataa ggtctaacat aaacttactt
    38581 aacaacaata aaagtatgtt agaaccgtgg gtaaactttg atattcctct tgaaaatatg
    38641 gaaactaagt atacaaaaac tatacttgga actgtaccca taagtgcaaa cattgatggt
    38701 ttaagagtaa aattagaaga tgaaatacca gaaagtgtta ttgggattgt caattctgac
    38761 aagttaatga actatgttta tttaatcact ttaaaagaaa cttttgatga tgttttagaa
    38821 gttttaaaag aatttaattt ttcagtggtt tcattgccaa atgaagaagg tacaccgtta
    38881 caagctatca agaaatacaa tgaaatgata attagacagg aaaacgtttc taaagacaaa
    38941 acagaggaaa ttaaaagaca tgcagagagt atacacatgc ttgaaaatct atatgatttt
    39001 tacactatag aaagagacca aaaaaagatt atagagagac ttgtcaaaac aaaaacaaca
    39061 ttctgtctta atggttggtt accaagcaaa agggcagatg agctaattaa agaaattaca
    39121 gaaaagtttg attgttgcgt tcagactgaa gaaggaagta aagaagaagg cttcccaatt
    39181 ttgcttgaaa acaataaact agtaacacct tttgaaagtg taactaacat gtacagctat
    39241 ccaagtacaa aagatattga cccaaataca attttaacat tcttttttgt tgtattcttt
    39301 ggaatgatgc taagtgacgc tgcatatggg ttaataattg cactagtctg tggatttgtt
    39361 gtatataaat taaagataca aaaaggtgaa ggaaatttaa ttaaacttat tggtatctgt
    39421 ggagtttcaa ctactgtatg ggggcttata ttcgggggtg ttttggggga tttaattcct
    39481 ataaaagcat taattaatcc tttagaggat gttatgacac ttatgggaat gtcgttactg
    39541 ttcggtatta tccatatata tgtaggtttg ggaataaaag catatacatt aataagaagt
    39601 ggaaaggtaa tagatgcaat ctttgacata ggtttttggt atttgtgtat aacaggtgta
    39661 tgtctactta taataccttt tgttgcaggg gacataggtg tattttcaga agtaggaaaa
    39721 tatttagcaa ttataggtgc tataggtctt gtacttactc aaggaagaag ctttaaaggt
    39781 attcctgtta agctttttaa aggattttca agtctctatg gcataacaag ttattttgct
    39841 gatatattat cttatacaag aattatggca ctttgtttaa caacaggagt tatagcacaa
    39901 gttatcaacc ttttaggagc tatagctggt ccgatacttg cagttgtaat cggtgttgta
    39961 ggacacacaa taaaccttct tataaatgca ctaggtgcat atgttcatac aagtaggtta
    40021 cagtatgtag aatttttcaa taagttttat gaaggcggag gagttccttt tgttccgttt
    40081 aagtataaaa caaaatatac aagcattaat aaaaaggaga tgtaaatatg gaatttttaa
    40141 acgcgttagg aaatggtcaa tttttggcaa tatcaggagc tgctatagca gcattatttg
    40201 caggtatggg ttctgctaaa ggtacttcaa tagcaggtca agccgcagca ggtgttgtaa
    40261 cagaagaccc tagtaaattc ggtcaacttc tagttttaca acttcttcct ggtacacaag
    40321 gtttgtatgg atttatcata gctttcctta ttttatcaaa agcagggatt attggtggag
    40381 atgcaatacc aacatcagct caaggtttac aacttcttat ggcaggactt ccaattggtt
    40441 tagttggttt agtatcaggt atagcacaag gtaaagcagc agcagcaggg gttggaatag
    40501 ttgcaaaaag acctgaagaa cttggtaaag ctataacatt tgcagcaata gttgaaacat
    40561 atgctctttt aggactactt gtttctttct tagcttacaa tggaattgca attggttaat
    40621 tatagattat aattcataag taaaaaaaat gaaaaggagg aagcactcct atgggtaatg
    40681 aacaaaaaat gattgacaga attatagctg atgccaaaca agaagcacaa gaaatattgg
    40741 ataaggctaa aagtgaggca gatttaaaag taaattcagc taatgaaaaa gctgaaaagg
    40801 aaatggcttc ctatacaaag cttgcagagg cagaagcaga aaaagcagct tctaaggaaa
    40861 tatcaggagc ttatatggag gctaaaaaac aaatattatc aaaaaaacaa gagattttag
    40921 aagaggtaat tttagaagct aaaaacaaac ttctaaatct taaagataat gaatatgaag
    40981 agattatact aaacatgatt gaaaaatcaa attgtacaga tgattcagag atagtattat
    41041 ctaaaaaaga taaaaaaaca ttaaaagatg tgctatcaaa aaaaggcatt aaagtgtctg
    41101 atgaaactag agatattact ggaggtttca tagttaaaaa aggtgacatt gagtacaatt
    41161 attcatttga agccataatt gcagtagagc atgaatatat tgaacaaatt gcagcagaaa
    41221 ttttgtttaa ttaaggaggg gttaaaaaat ggcagaagaa aaaacttatc cctatgccgt
    41281 tgcacgaata agagtgcttg aaaaacagct tcttaacaga caaatgttta ttcaaatggc
    41341 agaagccaaa agccctgaag actctttaag aattatagct gaggcaggtt atgctgatac
    41401 atcaaataat aatatacata attttgagaa tattttgact caagaattat caaaaacata
    41461 tgaaattctt aaaagtctag ctcctgaaga aaaatttgtt gatgtgtttc tttataaaaa
    41521 tgactatcac aatttaaaag tgctgattaa agaagaaatt tctggtgtag atggtgagaa
    41581 atatttaatt gatggaggta caattcctct tattaagctt agagaatctt tagcaaatcg
    41641 tagttttagt gatttaccta aggtaatgtc atcagctata ttagaggcat ttgatgttta
    41701 tagtaagaca caaaatggcc agatggttga tattgttcta gataaagcga cttttactag
    41761 tatgaaagaa actgctaaag aaagtcaaaa caaatttgta atagattatg ttatgaaagt
    41821 ttgtgattta acaaatctaa agagttttat aagagtcaaa aatatgaaga aagattttga
    41881 tatgtttatg aatgtgtttg tttcaggtgg ctcacttgat aaggaaaaat ttttagaagc
    41941 tttttcctca gatactccag catcatgttt taaatctact tcttactctg atgtttgtaa
    42001 aaatggcatg gatagtggtt ttactgtctt tgaaaaactt tgtgatgact atcttatgga
    42061 atatgttaga ggggcaaaat ttaagccact tacattagaa ccactaattg catatttata
    42121 tgctaaagaa tcagaaataa aaacaattag aattattttg actagtaagc ttaataatat
    42181 agacgcagat actataaaag aaaggctaag ggatgcttat gtataaggta ggagtagttg
    42241 gagataaaga tagcatcatg ggatttttag ctcttggaat agatatcttc ccagcctatg
    42301 atagtgacga aattaaaaaa agtatacata agttggttga agatgaatat gcgataattt
    42361 atattacaga acaggcatca ttgcttgcaa aagaatcaat agcaaaatac aaagattacc
    42421 aacttcctgc tattatagtt attccaggta ttggaggaag tatgggacta ggtatgaatg
    42481 aagtaagaga atctagtaaa cgtgctatag gtgcagatat attatttaaa gaatagatga
    42541 aagttgaata aaagacaatc tcaaatttta ttggtattaa agatatctac taataaaata
    42601 taggagggaa tatttaaatt ttgataaagt atatgattgc aggtgagaga atatgaaaac
    42661 aggcacaatt gtaaaggtgt caggaccgct tgttgtagcg gagggcatga gagatgcgaa
    42721 tatgtttgac gtcgtaagag tttcagataa acatcttata ggcgagatta tagaaatgca
    42781 tggagataaa gcttctatac aggtttatga ggagacttct ggtctaggac caggggaaga
    42841 agtagtttct cttggaatgc ctatgagtgt tgaacttgga ccaggtctta tttcaactat
    42901 ttatgatggt attcaacgtc cacttgaaaa aatgtatgat atttcaggta ctaatataac
    42961 taaaggggtt gaagtatctt cacttgatag aacaattaag tgggaattta aacctaagaa
    43021 atctgttggt gataaggttg tagcaggaga tatcattggt ggagttcaag aaacagcagt
    43081 agtagaatgt aaaattatgg ttccttatgg agttaaggga actataaaag aaatatattc
    43141 tggtgaattt actgttgaag atacagtttg tgttattaca gatgaaaaag gtaatgatat
    43201 acctgtaact atgatgcaaa aatggccagt tagaaaagaa agaccatata gagaaaagaa
    43261 aacaccagat tcacttcttg ttacaggtca aagagttata gatacatttt tcccaattac
    43321 aaaaggtggg gtagcagcta taccagggcc ttttggaagt ggaaaaactg ttacacagca
    43381 tcagcttgct aaatgggcag atgcagatat agttgtatat ataggctgtg gcgagcgtgg
    43441 aaatgaaatg acagatgttc ttcttgaatt tcctgaatta aaagacccaa gaacaggcga
    43501 gtcacttatg caaagaactg tgcttatagc aaatacatca gatatgccag ttgctgcacg
    43561 tgaagcttct atatacactg gtattacaat agctgaatat tttagagata tgggatatag
    43621 tgttgcactt atggcagact ctacatcaag atgggctgag gctcttagag agatgagtgg
    43681 tcgtctagag gagatgcctg gtgaagaagg ttatcctgca tacttaggtt cacgtcttgc
    43741 tcaattctat gagagagcag gaaaggtaaa ttgtctaggt atggatgaaa gagaaggaac
    43801 acttacagca attggtgcag tttctcctcc tggtggtgat acatcagaac ctgtcagcca
    43861 agcaacactt cgtatagtaa aagtattctg gggtcttgat gcatctttag catataaacg
    43921 tcatttccca gcaattaact ggttgactag ttattcactc tatcaggaaa aagttgatgt
    43981 atgggcagat aaaaatgtaa atgataattt ctcagctcaa agagctcaag ctatgaaact
    44041 tttacaagtt gaatctgaac ttcaagaaat agttcaattg gttggtgttg actcactttc
    44101 agatggagat agattgatac tagaggttac tcgttctata agagaggact tccttcatca
    44161 aaactctttc catgaagttg atacttatac atcacttcat aaacaatata gaatgatggg
    44221 acttatatta aaattctata agtcagcaca agatgctatc aagcaaaatg ttactataaa
    44281 cgatattatc aagctttcag ttcttgaaaa gattggtcgt gctaagtatg tagaggaagg
    44341 cgacatagat gcagcttacg attcaattga agatgaaata gacaacgagc ttgcagacct
    44401 tattaaaaag aggggggctg aagaactatg ataaaggaat ataagtcaat acaagaggtg
    44461 gccggtcctc ttatgctaat aaacggcgta gaaggtgtaa aatttgatga acttggagaa
    44521 attgaacttt caaatggaga gattcgccgt tgtaaagttc tagaggtaaa cggagatact
    44581 gcacttgttc agcttttcga aagctcaaca ggtataaacc ttgctgaaag taaagttcgt
    44641 ttcttaggaa agagtcttga ctttggagtt tcaccagata tattaggtcg tgtttttagt
    44701 ggaatgggta gacctattga tggaggtcca gaaattatac cagataaaag acttgatata
    44761 aatggagctc caataaatcc agcagcacgt gactatccgg ctgaatttat acaaactgga
    44821 gtttctgcca tagatggact taatacactg gttagagggc aaaaacttcc tatattctca
    44881 gggtctggtt tgccacatgc caatcttgca gttcagattg caagacaggc aaaagtacgt
    44941 ggaactgatt ctaagttcgc cgttgtattt gctgcagttg gtataacttt tgaagatgct
    45001 gaatttttta taagtgattt caaagcaact ggtgcaatcg accgttctgt agtgtttgta
    45061 aaccttgcaa atgacccagc tgtagagcgt gtatctacac ctagaatggc acttacagca
    45121 gcagaatacc ttgcttttga gcaagatatg catgtacttg ttataataac agatattaca
    45181 aactatgcag aggcattgcg tgaagtttca gcagctaaaa aagaagttcc aggacgtcgt
    45241 ggatatccag gatatcttta tactgacctt gctactatgt atgaaagagc aggaaaaatg
    45301 aaagggcatg aagggtctat aactatgatt ccaatactta caatgcctga ggatgataaa
    45361 acacatccaa ttcctgacct tacaggatac attacagaag gacaaattat acttagccgt
    45421 gaactttata aaaaagatat acagcctcct atagatgttt taccatcact ttctcgtcta
    45481 aaagataaag gtattggtaa gggtaagact cgtgaagacc atgcagatac aatgaaccag
    45541 ctttttgcag cttattcaag aggtaaggat gcaaaagagc ttatggctat acttggtgaa
    45601 tctgcacttt ctgaaattga tttaatgtat gctaagtttg cggatgaatt tgagaaagaa
    45661 tatgtttcac aaggatttag aactgataga actattgagc agacattaga aatcggatgg
    45721 aagcttctta gtatgttacc aaaaagtgaa cttaaacgta ttcgtgatga atattttgaa
    45781 aaatatatgc ctaaggagtg atatctgtgg ctagattaaa tataaatcca acacgtatgg
    45841 aaatgactag acttaagaaa ctccttaaaa ctgctacaag aggtcataag cttcttaaag
    45901 ataaacttga tgaacttatg aaacaatttc ttgagattgt aagagaaaat aagcgattac
    45961 gtgaagaagc agaaaatgct cttgatgctg cttataaaaa ttttataatc gcaagagcag
    46021 ttatgagtca ggagtatctg ggttcagcac ttatgatgcc aaagcaatct gtttcagtag
    46081 atgtttctac tagaaatata atgagtgttg atgttcctgt gtttgacttt aaaactgaaa
    46141 acaatcaaag tgatatttat ccttatggtc ttgcttttac atcaggtgaa ttagattctg
    46201 ctatggaagc tttctcagct gctatgcaac cacttttaag acttgcagaa agtgaaaaaa
    46261 gtgcacagct tcttgcacaa gagatagaaa agacacgtag acgtgttaat gctcttgaaa
    46321 atgtaatgat accaaattac attgagacta ttaagtatat agctatgaag cttgaagaaa
    46381 atgagagagc aagtactact agacttatga aagttaagga tatggtgctt aaaaaagcac
    46441 ttgaagaaaa gaaaaaaaat gatttggttg tataattaaa tacttataaa aataagtcta
    46501 acattctaat ttatagaggt taggcttatt tttatgttta aattaaaagt gtaaatagta
    46561 taaaaatcaa tacattgttt aaaaacagac tgtatttaac taaaaataat atatttaaca
    46621 aaaatttcta aaaattaacg aactgttaat ttacacttaa ctttatatta acaaattagg
    46681 tgtattatat aaacataagc aaaaacaata aaaaacaaat aaaaaaagaa aaaaacacaa
    46741 agggggaaga tatgaaagaa tttatattta cttgtctgtg cattgtagtg attacattta
    46801 tgacaagttg catatcaaca acaccacaaa ctactcaagg aaaaggaaat aataaactta
    46861 caatatatgc agcactagag gaagagcaga tagcttacta tatggaaggt tttagagaag
    46921 agtatcccaa tatagatgta gagatagtta tggattctca tggtgtaata gcttcaaaat
    46981 tattagcaga aaaagataat ccacaagctg atgttatatg gggattatca gcaatgaaca
    47041 tgatagaact aaaagaagat ggtgcacttg aagcatataa acctaaacac tatgataaag
    47101 ttgataaaaa attcaaagat actgaagatg atgtatcttg ggtaggaatg agtgtcccgg
    47161 aaacagcaat agtagttaat tataaggaac ttaagaaact aggtatagat attccaaaaa
    47221 gttatgaaga tttaataaaa ccagaatata aaggacttat aacaatgcca aatccagcat
    47281 catctggaac agggtatctt acagtatcag gccttattca aatgatgggt gcaaaagatg
    47341 cttacaatta catggataaa ttacataaaa atatagctac atatacacac tcaggttcaa
    47401 aacctgcgaa actagctggt tctggagagt atccaatagg tattacactt ggatatagag
    47461 ctacacaaca attatccagt ggagaacctg tagaagttgt atttccaaag gaaggttcag
    47521 gttgggactt agaagcaaat gccttagtta aaaaagataa tataaaaaaa gaagcaaagt
    47581 tatttttaga ttgggcaata agtgattcag ctatggatag atattcacat gaagtagcag
    47641 ttacttccat aaagacagat aatccagttc caaaaggtta ctctaaacaa ccatttgaac
    47701 agcttataaa agaagttgat ttaagttctg cggctaaaaa cagaagtaca gtacttaaaa
    47761 cttgggaatc taaatatggt tcaaaatctg aaagtaagta aagtttaaat taataattta
    47821 gatgaaagaa ttttagaaaa aaaggtagga tatagaattt aagataaaaa tataactata
    47881 taaggagaga taagatatga gttatttaaa aataaagaat gtgtttaaaa attatgacca
    47941 aaaaagagtt ttaaataata ttagtttgga tattgaagaa ggggaatttc tatgtttact
    48001 tgggcctagt ggatgtggta aaactacatt acttagaata atagcaggtc ttgaagatgt
    48061 aaatagtgga gatataattc ttcaggataa agatattaca aatttagaac catcaaagag
    48121 aggttttggt atagtatttc aatcatatgc attatttccg aatatgactg cttataacaa
    48181 tatagctttt ccactaaaag agagaaaaat ttcaaaagaa aaaatagata ataaagttaa
    48241 ggaagtactt gaaatagttg ggttgaccaa tgaagctcat aaatatccta aagcattatc
    48301 aggtggacaa caacagagga ttgcaatagc aagagcatta gcacttgagc cgaagttttt
    48361 acttttagat gaaccaatgt ctgcattaga tgcaaaggtt agacacaagc ttagaatgga
    48421 cattaaaagg ctacaaaaag aacttaatat aacgacaata atggtaacac atgaccaaga
    48481 agaagctata actatggcag acaaaatagc tattctaaat ggaggagata taatgcaaat
    48541 aggaactcca gaggaaatat accaaaatcc tcaaaaccta tttacagctc aatttatagg
    48601 agatacaaac tgttttgata atggagattc tatattaact gtaagaccag aatatgttca
    48661 aatagagaaa tcgacaaaag aaaattacca aggtataata tcaaatatag agtttagagg
    48721 gaatttatta agagttgaaa taaaagataa actaaatgaa aatttcataa taagtgatgt
    48781 ttctataaaa gagtgggtta atttaaattt agtagaaggt gaccttgtaa agataagtat
    48841 agacgaaaaa tactatttaa agtatccaaa agttaaagga gcataaaggt atgaataata
    48901 atgctatagg ttataaaagt ataagtctta aatcaaaaat gaatttagat ataaaaaaat
    48961 gtatgcttac agtattagtt atgtctttag taatattttt attggcacct ataatatatc
    49021 tatttgtaca ggctttttta gataaagatg gagtctttgt aggattacaa aactttcaag
    49081 aatacttggc ttctgaaact ctattaaatt ctctaaaaaa tacaatattt gtttcagtta
    49141 tatcaactgt aatatcacta gcactagcac tagtatatgc atatgcatta actagaacaa
    49201 atcttaaatt taaaggtttt tttaaatcat tagcaatgtt tcctatgttt gctccaacaa
    49261 tgatgcatgc aataggtcta gtatatttat ttgggaatca aggattggta actaatttac
    49321 ttggaataca tgttccaatt tacggagcag taggaataat actggcacag attatatatg
    49381 tattcccaca atcatttcaa atactttata tatctctaaa ttcaactgat tatagactat
    49441 atgaagctag taatactatg gggataagca agataagaga atttataagc ataacaattc
    49501 caagtataaa atactcttta ataagttctg cattcgtatc gtttacatta tgctttacag
    49561 attttggagc tccaaaggta ataggaggag agtttaatgt attatcaata gatgtttata
    49621 agcaaattat agggcaacag aatatgccaa tgggagcaac tgtatcaata ttacttttaa
    49681 tacctgcaat aatatcgttt atagtaacta aaaaaattga aaaaaatcaa aactcatata
    49741 taacttcaaa gtcaattcca tataaggtta aaactaataa gttaagagat agtattttag
    49801 gaggaattgt aggaattatt gcatttggta taatatctgt aatgttaact gtaatcttat
    49861 catcattaat atcagtttgg ccatatgatt taaggcttac actggaacac ttttctatga
    49921 aaaatagtat tgatggaatt aaaccattta taaattcaat aaaaatgtca ttattgacag
    49981 ccattctagg gacgagcttt gttttcttat ttgcatattt aaatgaaaaa acagaaaaag
    50041 ccccctattt aaaatcattt gggtattttt taagtacatt gcctatggca ttgccaggat
    50101 tagttttagg tatagcttat gtattattct ttaataaatt ggagtttgat tttatggata
    50161 caatatacct taaaaatctg tttaatggat tatatggaac attgcttatt atggttatat
    50221 gtaatatagt tcatttcttt tcagtagcat ttataacagc tactactgct attaagaaag
    50281 tagataaaga attggatatg gtagctaaat caatgggaat aaacagcgca tcaattctta
    50341 agaatgtaac tataccactt tgtttgccag cagttttaga gaactttatg tactttttcc
    50401 taaactctat ggttacaata tcagcactag tttttatata tactgcaagt tcaaaagtag
    50461 ctgcaatatc aattgtacaa ctagatgata aggggagtac tgcacaggca gcagcactag
    50521 ctgtgttaat attaatcaca aatatattag tgaaagcaat acatgaattt ataaagaatc
    50581 gtttagaaaa aagaacaaac tttaattaaa gaaattattc tacaaaatta taaatttaaa
    50641 aagtctattc tcacaattta ttatttacag aatagacttt ttaaatttat tattaatatt
    50701 atttattaat tttccttttg ttatcataca tttgagaatc tgcataatta tacttataaa
    50761 ataaagaaat atttattaaa attttctgta aaatttttag ttttactgga agattagatt
    50821 cagaatatta tcaagctaag tttgactaat tattaagttt cgcatcaaaa caatgtttta
    50881 atagtgttta cagttgaagt tttttataaa aagtttagtt cccgtttaaa atttatattt
    50941 attttgatat tttcttaatt tataatatat tatattaata catagttatt agaaataaga
    51001 cacaattaaa taattatata aaattgggag gttaaaatgg gaagggccaa atattatgat
    51061 atatatatag atttaaaaaa tagaatagaa aacaaggaat atttatacca agatttatta
    51121 ccatcagaat acacattaat agaagagtat aattgttcta gaaatacaat tagaagagct
    51181 atacaggaat tagcaaacca aggatatgtt caaagtaagc atggaaaagg agtatttata
    51241 atttacaagg ctaacaagca atcagagttt ttattaggag gaacagaatc atttaaagaa
    51301 tctgctatta gaaacaagaa agaatataaa acgaaagtag ttcattttga ggaaatggtt
    51361 atagatgata agaaaagtca aataactaac tttgaagttg ggacagaagt gtattatata
    51421 caaagagtaa gaattctaga aaataaacca tctattatag atcataatta ttttatgaaa
    51481 gatatagtaa aagatattaa tgaagaaata gcatctaatt ctatatatga atatatggaa
    51541 agtgaattaa atgagactat agtaacaaca aaaagaacta tgacagttga aaaagcaact
    51601 aaactagata aaaagtattt agaattagga gattataatt gtgttgcagt tgttagcaat
    51661 aatacttata atgcccaagg tataatgttt gaatatacgc agtctagaca catacctgat
    51721 ggattcatat tttttcatca atctcaaaga attaataata taaaatagag tacaatttgt
    51781 actctatttt atattattaa ttctttgaga gttatactca taaactttag cagctaagta
    51841 tatgaatgta ctagctgtcc aggtgaaaga tttatctcta agaccctctc ctgtaatagc
    51901 gttgaaattt tcagcaaagc cgtttttatc aactaattca caatatcttt tggcaatatc
    51961 tattgcaagt tcattttcac cacattcttc taaagcttca acaaataata gtgtagtagg
    52021 agcccaaata ggccctctcc aataagcatc atcttgatat tcatcactat ctatagcttc
    52081 tgttgcgatt ccccatttag ttaaatatct ttcgctagtg actaaatcta tcattttgtc
    52141 tctaatatat ttaggaagtc tatttcctaa aactaaagaa acaagaggaa gtaaagcgtt
    52201 gttagaaagt atttcaccag ttacagtttc gcgagctaca ggtaaatcat caactataaa
    52261 ataatttaag aataactttg taagttcatc tgctttatta gaccaatact ctttttcact
    52321 atttctgttt agtttttcag ctacttttga tagcatgtcc atagcattta ttataaatgc
    52381 tgttaaatca ggagtatcaa caaccatagc tcctttaaat attgtactat tatcctgtcc
    52441 agaatcattt ccatggtgat attcaaaaat accatccata tttgaatctt taaactttac
    52501 ataaaacaat acttgttttt ctatgtaatt ataaattttt tctaatgttt ctttagtaaa
    52561 gttaattttt ttcatcatct tactaaaaaa taatccttga ataggtggtt ttgtaaaatt
    52621 ccatctaata gtagaatcgc ttaaggaccc aggaatttga ccatattcat cttggtagtc
    52681 gaaaagtact gccatttggt caaaagctaa tttatcattt acaccagcta aagctaatgc
    52741 gttaaaacag tgatcccagc tccatgcacc taagaatgtt gagtttgaag caagtatagt
    52801 atatctcttt aggtatcctt gaggtttgac aaaagaagac caatttatat aactcgcttt
    52861 taaaagtgag tttttatatt tttcatctac tttaggttga gctagataat attcatcaaa
    52921 taattttttt gtgctattta gtgaagtttc aaagttatat tccttgtaat ctggaacttt
    52981 catatgagta ggaatgtctt ctataacaca tataaattca ttatcactat tacttttaac
    53041 atctattatt gaagtattat tagctttatt tgtagaagca cagtcatcta taaatatatt
    53101 ttgtgataag ccaaccttac cattaacaga gaatactaaa aacttagtta aatttttgta
    53161 gctatttata acacaatatt ctgaaccttt tttacccata aggtagttat attcaaaatt
    53221 gtatatggga agtgtatcta gtttaagacc tacatttttt cccttaccat agaatacgat
    53281 tttagaatct ccttcaaaac atatagatat actaccattg ttgaatttaa ttaatatact
    53341 aaaatagtta gcctcaaatt cataatctac aggcatgtta tttactgtag gtataatcct
    53401 tagtacatcc atatttttct ttgattttcc tcttaatgat tttaatgtaa atccaagttc
    53461 atctgaataa gaaatagaca tataagatcc aaagtaacta aacggaattt cttttatatt
    53521 catttggtat agtcctttca tgatttattt tatagattta ctctgcttgt ttatacaagt
    53581 aagtatatat ttaacttacc aaataataaa ataattatca agagttaatt tatcaaaaaa
    53641 ataaataaga aaatgttttc aaaaaactat tgactaaaat aatataaaat attacaataa
    53701 agttgttcaa acaagttact tgtttaaaca acttattact tataataaaa aagagaaagg
    53761 ataagtagat atgaggaaga ataagatact aaattcaaaa gaaagtattt ccaaaattat
    53821 tgagtatgtt gggggaaaag aaaatataca aagtgcaaca cactgtgtaa caagattacg
    53881 tttaatatta aaagatacta gcaaagcaaa tattagtaaa ctagaagaca ttgatatagt
    53941 aaaggggtgt ttcaatgcag gcggacagtt tcaaatagta ataggaactg gagtagataa
    54001 agtatataaa gatttaatag accaaacagg agcagaagaa gtatccaaag aagaaattaa
    54061 acaacaagtc aatgaaaagt caaataaatt tcaaaagttt ataagaatcc ttgcagatat
    54121 attcattcct atattaccag ctatagttgc atcagggtta cttatgggtg ttaataatat
    54181 gatagctaat ccagggattt tttatgagaa gtctgttata gaagtaaaca cagatatagc
    54241 tgggatttca ggtattataa atttaatagc aaacacatca tttacatttt taccagcatt
    54301 aataggttgg tcagctgcga agaaatttgg aggaaatcct ttattaggtg tagttttagg
    54361 tcttgtatta gttcacccag ctttgatgtc tgcatatgat tttgcagcaa atccatcagc
    54421 agcaccaaca tgggatatat ttggtatgaa ggttgctcaa gttggatacc aaggtcaagt
    54481 aataccagtt ttaatagcta catatatttt agctaaactt gaattattct taaagaaaac
    54541 tgttccagat gcagttcaac tagtattagt ttcaccaata gctttattaa ttacaggtat
    54601 gttaactttt gtagttatag gacctataac tatgacaggt gcaaatatga taactaatgg
    54661 agtagtatat ttatttgaag tagcaccagt tttcgcagga gcactatatt catttatttc
    54721 accaccatta gtaataacag gaatgcatca tttgttttta ggagtaaact tacaaatggc
    54781 aggaacttta ggatatgtaa cattgtggcc aatatcagag actgttactt tagctcaagg
    54841 tgctgccaca ttggcaatgt ttttcatact taaaaataat aagaatttaa ggggtgtatc
    54901 tattacatct actatatcag catggctagg aataacagaa ccagctatat atggtataaa
    54961 cttaagattt agatatccat ttatagcagt tatggtagca agtgcaatag gaggagcatt
    55021 tatatcatat cacaatgtta aagctacagc tgttggggtt ggcggagtat tttcattcct
    55081 ttcagtgatg cctcaatatt ggggagtata ttttacggga atggcaataa catttgtaat
    55141 aacaatagga ttaacatact tattctataa gagtggtaaa tttaaaacaa atgacaatat
    55201 ataaatataa ttcccttggt tttatatcaa gggatgttaa tatgcattgg atagatagga
    55261 gacaatatgt tagattttaa aaagagtata gtgtatcaaa tatatttaaa gtcgtttaat
    55321 gatacaacaa ataatggttt aggagattta aatggaataa cggaaaaatt agattattta
    55381 gaatttttag gtgttgatta tgtgtggatt actccatttt ttgtatcacc acaaaatgat
    55441 aatggatatg atgtagctga ttattataat atagacccta tatatggaac tatggatgat
    55501 ttagaaaatt taataaaaga agctaaaaaa agaaatatag gtatcatgct tgacatggtg
    55561 tttaatcata cgtctataga gaatgagtgg ttcaaaaaag cacttaaagg agatgaatac
    55621 tacaaagatt tttatatatt taaaaatcct aaagaagata aaagtgctcc aacaaattgg
    55681 gaatcaaaat ttggaggcaa tgcttgggaa tttgtagaag aatttaatca atattattta
    55741 catttatttg ataaaactca agcagattta aactgggaaa atcctaatgt aagaaaagaa
    55801 ttaaaaaata tattaaagtt ttggatagat aaaggtataa aaggatttag atttgatgtc
    55861 gtaaatttaa tatctaaacc agagaagtat gaagatgatt tacaagatga tggtagacgt
    55921 ttttacacag atggtaaaaa agtacatcaa tacttaaaag agatgtgtga agaaagtgga
    55981 atattagaaa atgatatgtt aactgtagga gaaatgtctt ctacgactat agaaaactgt
    56041 gtaaaatatt caaatccaga tgagaaagaa ttgtctatgt gttttaattt tcatcattta
    56101 aaagttgatt ataaaaatca aaataaatgg atgttgcaag attgtgattt tattaag
//
LOCUS       DBGJFK010000019        54421 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.019, whole genome shotgun sequence.
ACCESSION   DBGJFK010000019 DBGJFK010000000
VERSION     DBGJFK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54421
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.019"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            1..76
                     /locus_tag="ACOIAP_001375"
     tRNA            1..76
                     /locus_tag="ACOIAP_001375"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Phe,seq:gaa)
     gene            83..156
                     /locus_tag="ACOIAP_001376"
     tRNA            83..156
                     /locus_tag="ACOIAP_001376"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:117..119,aa:Met,seq:cat)
     gene            171..247
                     /locus_tag="ACOIAP_001377"
     tRNA            171..247
                     /locus_tag="ACOIAP_001377"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:205..207,aa:Ile,seq:cat)
     gene            265..341
                     /locus_tag="ACOIAP_001378"
     tRNA            265..341
                     /locus_tag="ACOIAP_001378"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:299..301,aa:His,seq:gtg)
     gene            350..425
                     /locus_tag="ACOIAP_001379"
     tRNA            350..425
                     /locus_tag="ACOIAP_001379"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Lys,seq:ttt)
     gene            433..506
                     /locus_tag="ACOIAP_001380"
     tRNA            433..506
                     /locus_tag="ACOIAP_001380"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:465..467,aa:Cys,seq:gca)
     gene            514..590
                     /locus_tag="ACOIAP_001381"
     tRNA            514..590
                     /locus_tag="ACOIAP_001381"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:548..550,aa:Arg,seq:acg)
     gene            603..678
                     /locus_tag="ACOIAP_001382"
     tRNA            603..678
                     /locus_tag="ACOIAP_001382"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:636..638,aa:Val,seq:tac)
     gene            754..1167
                     /locus_tag="ACOIAP_001383"
     CDS             754..1167
                     /locus_tag="ACOIAP_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638274.1"
                     /translation="MYIVIGNEIVDSEELKVIIDKNSKFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLISEQCNLASLSDEEKFDEYMTLSDELALNLEELMPKYTIINARAYKL
                     DEVDGVVKIILAVAYADLGHLKLSDVLMRISRQVD"
     gene            1480..4911
                     /locus_tag="ACOIAP_001384"
     CDS             1480..4911
                     /locus_tag="ACOIAP_001384"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HGZ2638275.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHHEEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKAEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNIKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYSKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPEEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5153..7081
                     /locus_tag="ACOIAP_001385"
     CDS             5153..7081
                     /locus_tag="ACOIAP_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGZ2638276.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISNYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLKNSELVEVEKAKAGDIVVVTKINSLK
                     TGDTISIDKDAEALENIDFPKPQIYYAVTPKNKGDEEKVASVLNRLVEEDPTLHSYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGKSDVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFAEEIFGGSVPKQYIPAVEKGIKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASVAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            7538..8002
                     /locus_tag="ACOIAP_001386"
     CDS             7538..8002
                     /locus_tag="ACOIAP_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGZ2638277.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGNQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8009..8503
                     /locus_tag="ACOIAP_001387"
     CDS             8009..8503
                     /locus_tag="ACOIAP_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HGZ2638278.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            8519..9544
                     /locus_tag="ACOIAP_001388"
     CDS             8519..9544
                     /locus_tag="ACOIAP_001388"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0046314 - phosphocreatine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HGZ2638279.1"
                     /translation="MKENIVMKSRVRLARNLNNYSFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAESDKSAVIVKKDKTVSIMINEE
                     DHIRIQTMCDDLNLEYAYSVANEIDDLLESSLEYAFSTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRIMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            9531..11978
                     /locus_tag="ACOIAP_001389"
     CDS             9531..11978
                     /locus_tag="ACOIAP_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGZ2638280.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKGLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWSKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12158..13531
                     /gene="radA"
                     /locus_tag="ACOIAP_001390"
     CDS             12158..13531
                     /gene="radA"
                     /locus_tag="ACOIAP_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGZ2638281.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVTINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     EVVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVIKDTKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            13534..14604
                     /gene="disA"
                     /locus_tag="ACOIAP_001391"
     CDS             13534..14604
                     /gene="disA"
                     /locus_tag="ACOIAP_001391"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning diadenylate cyclase DisA"
                     /protein_id="HGZ2638282.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAITNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            14693..15787
                     /locus_tag="ACOIAP_001392"
     CDS             14693..15787
                     /locus_tag="ACOIAP_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HGZ2638283.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYFIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKDIKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            15916..18093
                     /locus_tag="ACOIAP_001393"
     CDS             15916..18093
                     /locus_tag="ACOIAP_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638284.1"
                     /translation="MRKKIISFLATFIIILTSASQYIFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSVNENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVVFVELGDTYRLDLYKPNLNEKTYENMKNKIEKNIDVYLKNIFSMVGEND
                     TIYIASAFPSDLDYKNKRRLSPIVKLNGVGKGLLSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKKYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSVIVFSLLILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGAFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILALMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYIIVPMITLSVNLTALKE"
     gene            complement(18272..19123)
                     /locus_tag="ACOIAP_001394"
     CDS             complement(18272..19123)
                     /locus_tag="ACOIAP_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2638285.1"
                     /translation="MNRNSFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCTYHNTSILLQVPMSFLNKYIPDFK
                     NCYFDFKVNANDNNYKRNSSKVKLILENMREIKLSSPPAANLQFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTNINYKSPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILETHGFTNTKLFYRIFKEKFKCTPKHI
                     RKNLPKI"
     gene            19340..20506
                     /locus_tag="ACOIAP_001395"
     CDS             19340..20506
                     /locus_tag="ACOIAP_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HGZ2638286.1"
                     /translation="MYIKGVNLGGWLVLEKWMTPSLFEGTEAEDEYYLPRQLSRDVYE
                     SKIKTHRSEYITERDFAIIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFYWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGVCSWSQNPEYVEFTLNVLERLAKRYGMRRELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKDMARRSKPNSLEFLRDFYIKAYKVMRPYMS
                     EENVIVFHDAFELKSWKDFMKEEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIRDN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTAGGQSPLNGIESNIDKLSKDERRELYR
                     KIAKAQIDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            20528..22174
                     /locus_tag="ACOIAP_001396"
     CDS             20528..22174
                     /locus_tag="ACOIAP_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HGZ2638287.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVFGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDNGKKWISSLDWETREGYEKPGVICL
                     VEYCIEKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHGVTMGR
                     SKNIWGPYEKDLMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETPSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTEDNWLRMEDGSNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNKLGLQYYAPRISPLSFADVNSRTGYVRIRGQESRTSLNRVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIKGRKSYFEWSYDGEKYQRIGETFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIADESKDVD"
     gene            22272..23645
                     /locus_tag="ACOIAP_001397"
     CDS             22272..23645
                     /locus_tag="ACOIAP_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2638288.1"
                     /translation="MNKEVNVKATTIKYEKISFFERVSYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLISRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     ISAILLFSVPSSLGVTSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQDQYERGVL
                     SIFRMILATCGTLIINGLTLPLVEHFGNNLSAWTKTFFIFGIASIIVFFITFTGTKER
                     VKAVKQNKNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFAPINMVSNVSQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIAGQNYIG
                     VISASAIKGIGSAGIAATMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGGVLSIGGYVGTSATQSNSAIVSIKACFIYLPIFITILQIIIMFFYKLDKEYSTI
                     LNELNTK"
     gene            complement(23890..24987)
                     /locus_tag="ACOIAP_001398"
     CDS             complement(23890..24987)
                     /locus_tag="ACOIAP_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2638289.1"
                     /translation="MKKLYFRFIAYFTTGLFIFLVYFITLFILLNQLIYPEDSHKFLY
                     VIDSSIIYFPSTLIFTFCFITGGILFCLFLVRPLYLIISSISNLSRGNYTISEKAFTK
                     NGKLKWYNFMYREVIINIKDLGNKLQETEIEREKLEVAKTDWLASVSHDLKTPLSYIT
                     GYSSLMLNKNHSFSEEEMLTFLNNIYTKGIYIEKLIDELSLTFFIDSHNKIHLKHTQV
                     EIVSFLRNLIADITNNPKSEKHIFEFHTDLQHLNLVIDETLMYRAIYNLLINCVEHNP
                     SGTEIDVVLTQKSDEIYININDNGIGINPETLNDIFAKYYSSKNQNTQNKGLGLFIVK
                     QIIDAHEGNISVSSIMGKGTSFQIMLKQHKP"
     gene            complement(24992..25726)
                     /locus_tag="ACOIAP_001399"
     CDS             complement(24992..25726)
                     /locus_tag="ACOIAP_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2638290.1"
                     /translation="MNDKFKNSERILIVDDEEGLLTLLKITLNKEQYNNITCVSTGAK
                     ALECIENNQYDLIILDVMLPDYSGFDLCTNFRKKTIAPIIFLTARASDYDKLSGLAIG
                     GDDYITKPFNTMELVARIKAIFRRQQLERSVLCNHSENILVYNYGYIVLDMAHALLTV
                     SGKNVECTAKELELLEFFCQNPNRVFTTSHLYDKIWGLQGYGDEKTVTIHISKLRKKI
                     LDDNKPYKVITNLRGIGYKFIPPKGN"
     gene            25894..27345
                     /locus_tag="ACOIAP_001400"
     CDS             25894..27345
                     /locus_tag="ACOIAP_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl protease family protein"
                     /protein_id="HGZ2638291.1"
                     /translation="MIKSLKSRGISILLCGALIVGVMTGCTSKATSPKSSTPKSTPKT
                     VEKVTRANCEKQLKEVKAKYKKNPNDEAIRLEYAQILFKLGNITEAQEILNPLLNSKK
                     PSPDAIFLSARIEYLNGNYTQAEKLYDNLIEQYPDKFKSKAEDELALTYYQTNQYQKA
                     DKLSSVKTNNALLEMMKAFKDKHPNKIDWNGKKETVIPFVTGDPLPIIPMEINGKRIN
                     TIIDNGAPMFVVDEKIAEEIGINLASKEENTKFAGGNSIGINFGQANSLTIGDVNMEN
                     IPVMLGPFDGFEKLFKDYGNVHGIMGTTVLKEFVPTMDYPSGQLILRPRNEVGRDNLN
                     KMLTNDKILEEVPFTLASTHFMFGKGSINQKVGLNFFVDSGLGDEKGAGIVLTEEIMN
                     SLKIPMPELKKAEEGKGGMAGSDYKEGYFNLSSYGLGDLQLKNVLGYYFTGDTLDYDE
                     GIGFVRDGLISHHYLKNYKWSIDFDSMKMTFSK"
     gene            27549..28502
                     /locus_tag="ACOIAP_001401"
     CDS             27549..28502
                     /locus_tag="ACOIAP_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGZ2638292.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDSLTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            28540..29502
                     /locus_tag="ACOIAP_001402"
     CDS             28540..29502
                     /locus_tag="ACOIAP_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGZ2638293.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLRNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            29527..30513
                     /locus_tag="ACOIAP_001403"
     CDS             29527..30513
                     /locus_tag="ACOIAP_001403"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGZ2638294.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGVVPEDDYVIEIGKADIKKEGTDVTVITYGRMLQSV
                     EEAAENLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            30526..31572
                     /locus_tag="ACOIAP_001404"
     CDS             30526..31572
                     /locus_tag="ACOIAP_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HGZ2638295.1"
                     /translation="MVANKVKATPAARNQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTEKETIVSTNTSKFSE
                     KKETKIENENSSMFNTVEGVFEKPNPMRATVARRMSESYFSAPVFTFNIEVDATELKA
                     LRVKLIDTVKESTGVKLTMTDLIVMAVSRILPNHQALNSAWTDEGIFRYKDINIAIAV
                     GLDEGLYVPVVKSVNKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            31739..33469
                     /gene="lpdA"
                     /locus_tag="ACOIAP_001405"
     CDS             31739..33469
                     /gene="lpdA"
                     /locus_tag="ACOIAP_001405"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGZ2638296.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAAIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEAKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVEVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPKMDKDLSE
                     SLKYSLGKKGINVLTKKKVSEFKEEGNNILVCIEDEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGMNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPADEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            33875..36823
                     /locus_tag="ACOIAP_001406"
     CDS             33875..36823
                     /locus_tag="ACOIAP_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2638297.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSMLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKELQDSDNL
                     KLYKESDDKKEEINNNRENTDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFALESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADESKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETKLTNKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKQKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIVGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LNSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRNISEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEAITIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGIDIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKYNNTKVNFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKVKLNQINNLIDTNQISETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKNPIVWSKNKVKIILLLAVDQKCFNPLSTLLSFIETDEFKQIKNIKDRDFIRE
                     MILDGVNENN"
     gene            36801..37265
                     /locus_tag="ACOIAP_001407"
     CDS             36801..37265
                     /locus_tag="ACOIAP_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2638298.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKASYIQ
                     AVIAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            37344..37646
                     /locus_tag="ACOIAP_001408"
     CDS             37344..37646
                     /locus_tag="ACOIAP_001408"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2638299.1"
                     /translation="MGVTNVTKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLIKDVLEKLEL"
     gene            37708..39072
                     /locus_tag="ACOIAP_001409"
     CDS             37708..39072
                     /locus_tag="ACOIAP_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HGZ2638300.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIIMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMIIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGVAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSESAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     FIEE"
     gene            39107..39580
                     /locus_tag="ACOIAP_001410"
     CDS             39107..39580
                     /locus_tag="ACOIAP_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638301.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYINFNLNIYSF
                     LIIVCTYGIFNTFISSSNPKKIIIDNKCIHFSSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINEGNLFKGRYWIRTNMFNNSIELYSYLIELEECLYPDSLKFRNKRFENKNI"
     gene            39743..40393
                     /locus_tag="ACOIAP_001411"
     CDS             39743..40393
                     /locus_tag="ACOIAP_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HGZ2638302.1"
                     /translation="MLLDKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLIPSDIVIVDVDGNVIDGKWKASVDLPDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSNKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            40569..41501
                     /locus_tag="ACOIAP_001412"
     CDS             40569..41501
                     /locus_tag="ACOIAP_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HGZ2638303.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVHHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLLTLGLGVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSDKSTESNATKSVSSKVTNIKFLLEKNISYFLDYCVEYLKSNIKNIKELELDEED
                     IKNVYNLVEDKYKKIEWTYGKTPKFQVVLPFNNKSKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            41776..42489
                     /gene="ispD"
                     /locus_tag="ACOIAP_001413"
     CDS             41776..42489
                     /gene="ispD"
                     /locus_tag="ACOIAP_001413"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGZ2638304.1"
                     /translation="MYSVIIVAAGSGRRMHLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKELDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERSLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            42486..42971
                     /gene="ispF"
                     /locus_tag="ACOIAP_001414"
     CDS             42486..42971
                     /gene="ispF"
                     /locus_tag="ACOIAP_001414"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HGZ2638305.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIENMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    43066..43273
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            43337..45052
                     /locus_tag="ACOIAP_001415"
     CDS             43337..45052
                     /locus_tag="ACOIAP_001415"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGZ2638306.1"
                     /translation="MKMSKMFMPTLKEVPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSTEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNVASEKEEMKELEEVYTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGVVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDRDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAEKIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKFRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            45174..46619
                     /gene="proS"
                     /locus_tag="ACOIAP_001416"
     CDS             45174..46619
                     /gene="proS"
                     /locus_tag="ACOIAP_001416"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGZ2638307.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRIEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAVCDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            47063..48544
                     /gene="gltX"
                     /locus_tag="ACOIAP_001417"
     CDS             47063..48544
                     /gene="gltX"
                     /locus_tag="ACOIAP_001417"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGZ2638308.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHDEGVVLDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSIERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALKEKIEKAEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            48765..48920
                     /locus_tag="ACOIAP_001418"
     CDS             48765..48920
                     /locus_tag="ACOIAP_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638309.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            49065..50462
                     /gene="cysS"
                     /locus_tag="ACOIAP_001419"
     CDS             49065..50462
                     /gene="cysS"
                     /locus_tag="ACOIAP_001419"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGZ2638310.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDGFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            50465..50860
                     /locus_tag="ACOIAP_001420"
     CDS             50465..50860
                     /locus_tag="ACOIAP_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III domain-containing protein"
                     /protein_id="HGZ2638311.1"
                     /translation="MEKTELVTMSPLVLAYLGDTVYETYIREHLIRQNTQKKVNDLHK
                     LAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKHATGFEA
                     LVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            50966..51724
                     /gene="thyX"
                     /locus_tag="ACOIAP_001421"
     CDS             50966..51724
                     /gene="thyX"
                     /locus_tag="ACOIAP_001421"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HGZ2638312.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            51737..52474
                     /gene="rlmB"
                     /locus_tag="ACOIAP_001422"
     CDS             51737..52474
                     /gene="rlmB"
                     /locus_tag="ACOIAP_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGZ2638313.1"
                     /translation="MANIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEHKYYELDELIDLVKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLGKSK"
     gene            52477..53004
                     /locus_tag="ACOIAP_001423"
     CDS             52477..53004
                     /locus_tag="ACOIAP_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HGZ2638314.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            53069..53716
                     /gene="sigH"
                     /locus_tag="ACOIAP_001424"
     CDS             53069..53716
                     /gene="sigH"
                     /locus_tag="ACOIAP_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HGZ2638315.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            53790..>54421
                     /locus_tag="ACOIAP_001425"
     CDS             53790..>54421
                     /locus_tag="ACOIAP_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006568224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGZ2638316.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTD"
BASE COUNT        22085 a         5860 c        10176 g        16300 t
ORIGIN      
        1 gcccagatag ctcagtcggt agagcagggg actgaaaatc cccgtgtcgg tggttcgatt
       61 ccgcctctgg gcaccagaat gtggcggtat agcttagttg gctagagcgt tcggttcata
      121 cccgaaaggt cataggttcg actcctatta ccgctactag aatttaatgt gggccattag
      181 ctcagttggt tagagcgccc ggctcataac cggtaggtct ggggttcgag tccctgatgg
      241 cccaccacat taaattaaat tatggtgggt atagctcagt tggttagagc gccagattgt
      301 ggctctggag gtcgtgagtt cgactctcat tatccacccc aacttatatg gtctattagc
      361 tcagtcggta gagcacctga cttttaatca gggtgtcccg cgttcgagtc gcggatagat
      421 caccaaaaag gtggcgacat agccaagtgg taaggcagtg gactgcaact ccttgatccc
      481 cagttcgaat ctgggtgtcg cctccaataa aatgcgctca tagctcaact ggatagagtg
      541 tctgactacg aatcagaagg ttaggggttc gaatcccttt gggcgcacca tataaatagc
      601 gagggattat agctcagctg ggagagcacc tgccttacaa gcagggggtc acaggttcga
      661 gccctgttaa tcccaccagt gcaaacctct agtaatttta ctaggggttt tatttttgat
      721 tgaaaaagtt tttatattta ggaggtaaga aacttgtata tagtaatagg aaatgaaata
      781 gttgatagtg aagaacttaa agtaattata gataaaaata gtaaatttaa agtagaaaag
      841 gatttaagta aaagcacaaa aagagaagat gtaatagcat atcagttaag tatagattta
      901 aattatttag attctcttat aagtgagcaa tgtaatttag ctagtttatc tgatgaagag
      961 aaatttgatg aatatatgac tttgtctgat gaacttgcac tgaatttaga agaacttatg
     1021 ccaaaatata caataataaa tgctagagca tataaattag atgaggtaga tggagttgta
     1081 aaaataatct tggctgtagc atatgcagat ttaggacact taaaactttc tgatgtatta
     1141 atgaggatat ctagacaagt agattaggat acgaatgaat atgaactata ttaaaaaaat
     1201 gtataaaatc ttacgtaaag atgaaaataa ttatgtaaac acagaaaaaa acagtataaa
     1261 atcaagtcaa ttgtagaaat tttcacataa attcatctga aattctataa aaaatgcctt
     1321 aattttaatg aggtaaatcg agtttacaca gtctaaaaat tacttatatt tataaattta
     1381 tcttattaat taaggaactt tcttaaacat cttcaaaaat aaagtatttt agtctataat
     1441 ctttaatatt acacaaacaa taaaggagaa gaatagagta tgcttaaaaa gtttaataaa
     1501 atactagtgg ctaatagagg cgaaatagct ataagaatat ttagagcctg ttcagaattg
     1561 gggataaaaa gtgttggtat atatagtaag gaagataaat atggcttatt tagaacaaaa
     1621 gctgatgaat catatttgat aggagaaggt aaagggccaa tagatgcata tctagatatg
     1681 gatggaataa tagacctagc aaagagaaaa aaagttgatg ctatacatcc aggatatggt
     1741 tttctagcgg agaatgcaga atttgctcgt aaatgtgaag agaatggaat tacttttata
     1801 ggaccatcat ctaaagtaat gaatatgatg ggggataaga ttaactctaa aaaaatcgca
     1861 aaagaagtta atgttcaaac tataccagga gtagaaaaag caataagaag tactgaagaa
     1921 gcaaaggaag ttgcaaacaa aataggctat cctgttatga taaaagcatc taatggtggt
     1981 ggcggtagag gtatgagaat tgtacatcac gaagaagact tagagcttga atatgaaact
     2041 gcttgcagtg aatcaagaaa agcttttgga gaagatatta tatttataga aaaatatata
     2101 gctgatccaa aacatataga agttcaaata ttaggagata actatggaaa tatagttcac
     2161 ttatatgaaa gagattgttc tgttcaaaga agacatcaaa aaataataga atatgcacca
     2221 gctttttcgc tagatgataa agtaagaaaa gagatatgtg aagatgcagt taagctatca
     2281 aaacatgtgg gttattctaa tgcaggaaca ttagaatttt tagtagatgc aaatggcgga
     2341 cattatttta tagagatgaa cacaagagta caagttgaac atactgtaac agagatggtt
     2401 acaggaatag atatagttca aagtcaaata ctaatagccc aaggttacag tttagatagt
     2461 gaagaaatca atataaaatc acaagatgat gtggaaataa gaggttactc tatccaatgt
     2521 agaataacta cagaagaccc taagaataaa ttcatgcctg atacaggtaa aattcaagtt
     2581 tatagaactg gttcagggtt tggtataaga ctagatggag gaaatggatt tacaggggca
     2641 aacataagtc ctcactatga tagtttattg gttaagacaa tatcttggga tagaacattc
     2701 caaggagcaa taaataaaac tataagatct ataaaagaac ttagagttag aggtgttaaa
     2761 actaatgtag gattcctagt taatgtttta aataatccta tattctcaaa tggtaaatgt
     2821 agtactaaat ttatagatga aaacccagat ttatttgaaa taacagaaag taaagacaga
     2881 ggaacaaaat tacttcagtt tataggagat gtaattgtaa atgataatgc ttgcaaggaa
     2941 aagccattat ttgatgcatt acatgaccca agaatggata aggatggttc aaaagcagaa
     3001 ggaagtaaaa tactttttga taagttaggt aaatctgcat atatagaaaa gataaaaaat
     3061 gataagaaat tattattaac agatacaaca atgagagacg cacatcaatc attattagca
     3121 acaagaataa gaacatatga cttattaaaa gctgctaagc caacagaaaa atatcaaaaa
     3181 gatttattct cacttgaaat gtggggagga gctacttatg atgttgcata tagattttta
     3241 aaagaatcac cttggcgtag attacaaaaa ctaagagaag aaataccaag tataatgttc
     3301 cagatgttgc ttagagcatc aaatggagtt ggatataaaa actacccaga taatgtaata
     3361 gaagaattta caaaagaatc tgcgagacaa ggtatagatg tatttagaat atttgactca
     3421 ttaaactggg ttgaaaatat gaaaccatct ataaatacag ctttagaaac tggaaaaatt
     3481 gttgaagcaa ctatgtgtta tacaggtgat atactagata agactaaaac taagtataat
     3541 ctagaatatt atattaaaat ggcacaagaa ttagaaagct taggagcaga tataatagca
     3601 ataaaagata tgtcaggact tcttaaacca tattcagcat acactctagt taaagagtta
     3661 aagaaaaata taaaagcacc aatacattta cacactcatg atacaagtgg aaatggtgta
     3721 gcaacttgtt taatggcatc agaagctggt gtagatataa ttgacgctgc attagaatct
     3781 atggcagggc ttacaagtca accatcactt aatgctatag tagaggctct taaaaataca
     3841 gaaagagata caggtataga tttatttgga tatgatgagt taggtaaata ttataaggat
     3901 ttaagaaaag tttatagcaa atttgaaagt gatttaacga actcttgcgc agaaatatat
     3961 aattttgaaa taccaggagg tcaatataca aacttaaaac ctcaagctga tagtttagga
     4021 ttagttaata gatttgatga agttaaagaa aaatataaag aagctaatga agttgtagga
     4081 gatataataa aagtaactcc atcttcaaag gttgtaggag atttagctat ctttatgact
     4141 aaaaataaat tagataaaga caatataata gaagaaggta aaaatttatc attcccagat
     4201 tctgttgtgg attattgtaa aggtatgatt ggtcaaccag aaggtggaat accaaaagat
     4261 ttacaagaag tagttctaaa aggtgaagaa gctatcacag taagaccagg ttcattatta
     4321 ccagaagaag attttgatga aatagctaaa tatctaaatg aaaaatatga tataaatgct
     4381 aacataagaa atgttataag ttacgcttta tatccaaaag tatatgaaga ttatatcaaa
     4441 catttacaac attataatga tatatctaaa cttgaaagtg atgtattctt ctatggatta
     4501 aataaaaatg aagaatgtga agtggaaata gaagaaggta aagtattaac aataagatta
     4561 gttgaaatag gtgaagttaa ggaaaatgga tttagaacta taggatttga gctaaatgga
     4621 atggttagag aagtagaaat aaaagataag aacttctctg gaaaaattaa taatgttgaa
     4681 aaagctgata tgaatgaccc tcttcaaatt ggagcaagca taccaggaaa agttataaaa
     4741 ataatggtta aagaagaaga tgaagtaaaa gcaaatcaac cattaatcgt tatagaggct
     4801 atgaaaatgg aaactataat agttgccaag actgatggag tgattaagtc aatcaaagta
     4861 aaagaagatg atatggttga agacaaacaa ttattaatga taatgaagta attaaattaa
     4921 aataaactaa aaagcactct gaaatgttta ataaaaaatg ttttagagtg tttttattta
     4981 ttttaattaa atatttgtta aaaaaaagag gacaatcatg tccatatgta gaaataaagt
     5041 tagtaaggaa aatgttatct aaaaattcta aatatagtaa atattttccg taatatttct
     5101 taggaaataa cagcaaagag aaaatacata aatttaaaag gtgggtgctt atatgaaggt
     5161 ttatgatagt aaaatgttga gaaatgtagc ggtattagga catagcggat gtggaaaaac
     5221 aaatctaatc gaaactatag cttacacagc aaacactaat aagataccta aattaacaga
     5281 caaggtaaat atgacttata gcatgggatt aatacctata gagtataatg attataagtt
     5341 taacttattg gataccccag gatattttga ctttagcgga gacgttgtgt catctcttag
     5401 agcaagtgat gcagcaataa tagtaataga tgcaacagcg cctattcaag ttggtacaga
     5461 gaaatcatta gaactaactg agagtattcc taagataatg tttataaata aaatagataa
     5521 tgaaaaagca agatataaag acgcaatagc aatgttaaga gaaaagtaca acaataagat
     5581 agttcctatg ataagtccta tatacaaaga taaaaacttt gtaaagttac ataatgtttt
     5641 tgaaaacata gatgatttag aaggtgaatt taaggaacaa gctatgagtg ttaaagaagc
     5701 attaatggaa cttatagcag agacagatga ccaaatatta gataaatatt ttaatggaga
     5761 agaattaact acagaagaaa tacaaaaagg tattattata gggatacaaa gaggagatat
     5821 tatacctgta atatgtggtt caactataaa taatatagga acaaaagaaa tattagatac
     5881 tatatcaaat tacctagaac ctatttttac ggaagaaagt aaaccattta gaggattagt
     5941 atttaagact atggttgacc catttgttgg taaaatgtca tatataaaaa ttactgaagg
     6001 tgtactttct aaagataaag atgtctttaa tataaataaa aatgtaaagg aaaaaatagc
     6061 taatatatat acattgaaaa atagtgaatt agtggaagta gaaaaagcta aagctggaga
     6121 tatagtagtc gtaactaaaa ttaactctct aaaaacagga gataccatat ctatagataa
     6181 agatgcagaa gctttggaaa atatagattt ccctaagcca cagatatact atgcagtaac
     6241 tcctaagaat aaaggtgatg aagaaaaagt agcatctgta ttaaatagac tagtagaaga
     6301 agaccctaca ttgcattctt atagaaacac agagacaaaa caagcacttt taggagggca
     6361 aggagaactt catataaaaa caattaaaaa taaaatgaaa gataaatttg gtgttgatgt
     6421 tgaattaaat gaccttaaag ttccttatag agaaactata aaaggaaaat cagatgtaca
     6481 aggaaaacat aagaaacaat caggtggtca tggtcaatat ggagatgtaa aaataagatt
     6541 tgaaagatgt gaatctgatt ttgaatttgc agaagagata tttggaggtt ctgtaccaaa
     6601 acaatatata cctgcagttg aaaaaggtat aaaagactct atgcaaaaag ggatattagc
     6661 aggttatcct gttacaaaca taaaagccac gctttatgat ggttcatacc atgatgtaga
     6721 ctcttctgaa atggccttta aaatggcagc aagtgtagct tttaaaaaag gtatggaaga
     6781 agcacatcca atactactag agcctataat gaaacttaag ataactgttc cagaagaata
     6841 tatgggagat gttatgggtg atataaataa gagaagagga aaaatatttg gaatggaacc
     6901 agatgacaaa ggtaaacaaa taatatttgc agaagctcca caggcagaga catttaaata
     6961 tgcaatagat ttaagagcaa tgacacaagg cagaggatac tttgaaatgg agctagagag
     7021 atatggagaa gttccatcac agtttgcgga aaaaataatt gggttagcta ctgcaaagta
     7081 atgaacaaaa ataaatagaa taataagtaa ttaatagata ctattaaaaa tatgtttagg
     7141 attttaacta ggtataagtt tatgttaagt aaacttatac ctagttttta tatgttttta
     7201 atagataaaa aaatataaaa tactttcttg aatattttaa taaaaagaaa gtattttatt
     7261 attattattt ttacaaatgt ttagcaataa agatgagaag gtatatttaa aatatagagt
     7321 atttaaaatg ttgaaatcta atcatgaagc aaaaaaatag agtttggtta tcataaatat
     7381 agtaaataaa aactcgtaat taatgaaaga ataaattcat atctaaattt ctataaaaaa
     7441 tttaaattta tacaatttag ggctttaaaa atttaaataa taggtgtaaa ataatagtca
     7501 aagaaagtca aaaataaaaa ggtgtgtggt gatattaatg gcaactatga cagatataat
     7561 tgaaaaattt attaaagatt tgatggaaga agataatagc atacaaattc aaagaaacga
     7621 actagcaaac ttgtttagtt gtgcaccatc acaaataaat tatgtcttaa caacaagatt
     7681 tacaatagat agaggatatt acattgaaag taaaaaaggt ggcggaggat atgttcaaat
     7741 agaaaaaata cgaaaaagta aagatggaca tattagagaa ctgttaaatg aaaaaatagg
     7801 aaatcaaata tcctataaaa aagcaaaaga attattggaa ggtttaaaag agtcagactt
     7861 gattaacgaa agagaattaa aattaatatt atatgcaata gatgataaat cattatgtat
     7921 gccaatatat gaattaaaag agaaggtaag gtctaatatt ttaaagaata taataatagg
     7981 attatttagt atagaggagt gataatttat gctatgtcaa aaatgcaata agaataaagc
     8041 gtctgtatat tataataaga tagtcaatgg agaaaaaaca gagatgtatc tatgtagtga
     8101 gtgtgcaaaa gagaatacag aaatgaattt taatttagat atgccttttt caatgatgga
     8161 tatattttct aatttaggtt ttcaacctaa aaaagaactt gaggaaaagt tagtttgccc
     8221 taaatgtaat acaacatata gtgaatttaa gaataatggt agatttggat gtagtgaatg
     8281 ttacaatgca tttagtagtc aagtaaatcc aatgcttcaa aatatacatg ggcatataga
     8341 acatacagga aaagcaccta aaaaatcttt ttataaaata agtgtagaaa atgagattaa
     8401 agaattaaaa gaagatttag atagagctat aaaaaatgaa gaatatgaat tagcggctca
     8461 atttagagat aaaattaaat acttaaaagg ttctattgac taagattgga gtgatattat
     8521 gaaagagaac atagtcatga aatcaagagt taggctagct agaaatttaa ataactattc
     8581 ctttccaaat aaattagata aagaatgtgc catggaaata atagaaaaag taaaaaatgc
     8641 atttataaat tctaacttag aacaaaaaga agaatttgat ttctataaaa ttgaagattt
     8701 agaccaatct aaaaaaatgc ttatggttga agaacatata ataagcccgg atttagcaga
     8761 aagtgataaa agtgcagtta tagtaaaaaa agataaaacg gtaagcataa tgataaatga
     8821 agaagaccat ataaggatac aaactatgtg tgatgattta aacttagaat atgcatatag
     8881 tgtagcaaat gaaatagatg atttgttaga atcaagttta gaatatgcat ttagcacaaa
     8941 gctaggttat ctaacatctt gtccaactaa tacaggaaca ggaatgagag cctctgtaat
     9001 gatgcattta ccagcactaa gtcagctagg ttatatggat gaactttata aaatttcatc
     9061 acaaataggt atagcaatta gaggtatata tggagaacga acagaagcat taggaaatat
     9121 atatcaaata tctaatcaac ttacacttgg aagaacagag tctaatatta tagaaaatgt
     9181 aagtggactt acaaaagatg caatttcaaa agaaataaaa gcaagagaaa tattgcaaaa
     9241 aaaattaggt ataaaattag aggataaaat atttagatcg atagggacac ttgaaaattc
     9301 aagaataatg agtagtgcag aggcaatgag ccacctatca aatataaaaa tgggaataga
     9361 aatgaactat atagataaac tagatttaag agctatagaa caacttatga taggtataca
     9421 accagcacat cagtcaataa tgtataagag tgatgatgtt gagaatagag atataaatag
     9481 agcaacatat attagagaaa ctttggaaaa attaagagga gggatgaatt gtgaacttca
     9541 atagatttac acaaagagct aaaaaagcta ttgatttagc gtttgaatct gctaaaggtc
     9601 tagggcataa tattgtcgga agtgaacata tacttttagg tcttttaaga gaagaagaag
     9661 gtatagctgc taaagttcta agtaaagttg gatttacaga agcttattta gaaggcaaaa
     9721 tagttgatat ggaaggtaag ggagaagaaa tctcagaaga tatagtatta agtccaagaa
     9781 gtaaacaaat acttgagtta tcaggcatgt ttgctaataa attaaaaaca aattatattg
     9841 ggactgagca tatattatta gcaattattc aagaaggtga aggaatagct aataagattt
     9901 taaattatgc aggagtaaat gataggactt tagcccaatt aacaattgat atgatgggta
     9961 ttagtgataa aaatcaatac aaagcagaaa atagttacac gggcaaccag aatcaagcag
    10021 aatctaaagt acttgataag tatggaagaa atcttacact atatgcaaag cagaataaaa
    10081 tagaccctgt aataggtaga gaaaaagaaa tccaaagagt aatacaaata ttaagcagaa
    10141 gaactaaaaa taatccagtg ttaataggag acccaggagt aggtaaaaca gctatagctg
    10201 aaggtcttgc tacaaatata gccttaggaa atgttccaga aacactaaaa aacaaaactt
    10261 tatactcttt agagatgggg tcattattgg ctggggctaa gtatagagga gaatttgaag
    10321 aaagaattaa agaagttgta gatgaagttg ttaaaaatgg aaacataatt ttatttatag
    10381 atgagatgca tacaataata ggagctgggt ctactggaga aggctctata gatgcttcaa
    10441 atatattaaa accagcttta gcaagaggag aaatacaagt tataggtgca acaacaattg
    10501 atgaatatag aaagcatgtt gaaaaagatt ctgctctgga aagaagattc caaccagtta
    10561 tggtagatga gccaactaaa gaggactcaa taaaaatatt agaaggatta agagataaat
    10621 atgaagctca tcataaagtt aaaataactg atgatgctat aaaggcggct gtagaattat
    10681 caactagata tatatcagac agatatctgc cagataaagc tatagacttg attgatgaag
    10741 ctgcatcaaa agtaagatta aaagaaaata cacctccatc agagataaaa aaattagaac
    10801 tagaaataga aaatatagat aaagaaaaag aagaagcagt aagatgtcaa gactttgaga
    10861 aagcagccaa aataagagat gaacaaggtc tacttaaaaa acaattagaa gatgttagag
    10921 agagatggag caagtcatct aagcattcag atttagttga tggagaagtt attgctgaag
    10981 tagtaggctt atggacagga atacctgtta ataaaattct tgaagaagag gctgatagac
    11041 ttttaagact cgaggaaata ctacacaata gagttatagg ccaagaacaa gcagtaaaat
    11101 ctatctcaaa ggcaatcaga aggtcaagag caggtcttaa agaccctaat agaccaattg
    11161 gttcattttt atttttaggt ccaacaggag taggtaaaac agaattatct aaggcattgg
    11221 cagaagtaca atttggagat gaaaatcaaa taattagaat agatatgtct gaatatatgg
    11281 aaaagcatgc tgtttcaaga atgataggtt cacctccagg ctatgtaggt catgatgaag
    11341 gtggtcaatt aactgaaaaa gtaagaagaa atccatattc agttatctta tttgacgaga
    11401 tagaaaaagc tcatccagat gtatttaata ttctattaca aatcctagat gatggtagac
    11461 taactgattc aaaaggaaga actgtagact ttaagaatac cattgtaata atgacatcaa
    11521 atgttggtgc atctacaatt ggtagacaaa aaactttagg gtttagtata gctaaaggag
    11581 acgaagaaga aaaatctcag tatgaaaaaa tgaaagaaaa tataatgggt gaattaaaac
    11641 aaagattcag accagagttt ttaaacagaa tagatgatat aattgttttc cattcattaa
    11701 atgaaaatca tatatcaaaa atagtacttt taatggcagc aaaactacaa gagagattaa
    11761 aagaaatgga tataaaatta gaaatgagtg atgaggctgt taaattaatt tctaaatctg
    11821 gatttgactt agaatatgga gcaagacctc ttaaaagagc tttacaaaaa gagttagaag
    11881 atgagttgtc tgaagcaatc ttaaaaggca atgtgaaaaa gggaagtaat gtagtagcaa
    11941 aagtcaaaga tgaaaaaata gtttttgaaa ctaaataatt taatagagtt gcattttaaa
    12001 atattgcaaa tataagcttt ataatctaaa caaaatttta agggcaatga atctataata
    12061 attcattgtc cttaattatt ttatttaatc tttacatatt gtctttcaga tatgctaaaa
    12121 ttatagtata gaataataga ttaaggatga taaaagtatg gcaaaaataa aaacaaaata
    12181 tgtatgtcaa tcttgtggat atgaaacagc taaatggctt ggtaaatgtc cagaatgtac
    12241 aaaatggaat acattcgtag aagaaataga ccaaaaaagt accaaaaaag aggtctttat
    12301 aatagataaa tcttcgtcta aaccagtaac tataaactca atagaaagta aagaagaaga
    12361 gaggtttaca acagatataa atgaattaga tagagtgctt gggggaggta tagttaaagg
    12421 ttctttagta cttgttggtg gagaccctgg tataggtaaa tcaacacttt taatccaagt
    12481 atctagcaat gttgctaatt taggaaaaac tgttttatat ataactggag aagaatcaga
    12541 atctcaaata aaaatgagag ctaaaagatt aggtattaac tcagaaaatt tatatatatt
    12601 tgctgaaaat aatttaagta taattgaatc ttatttagaa gttgtaaatc cagaattaat
    12661 aattctagac tcaattcaaa ctgtcttcag tccagaaata tcctcggcac caggaactgt
    12721 cagccaaatt aaagaaggta cttcaaaatt catgaaaatt tctaaaaaaa tgggaatttc
    12781 aacattcata gttgggcatg ttacaaaaga aggttcacta gcaggaccaa aattattaga
    12841 gcatatggtt gatactgttc tatattttga aggagaaaga tataatactt atagattagt
    12901 aagagctgtt aaaaatcgat ttggctcaac taatgaactt ggagtatttg aaatgaggga
    12961 tttaggatta gtggaacttg ataatccgtc taaaatttta atctctgaaa aaccaaaaga
    13021 tgtagcaggt tcagtaataa tatctactgt agaaggtacg agaccaatgt tacttgaatt
    13081 acaagcatta gtttctccta caagttttgg tataccaaaa agaacatcta caggagtcga
    13141 ttacaataga gtaggtatgt tattagcagt attagaaaaa cgtgttggtt tgcaaataca
    13201 aaatcaagat gtctatataa acatagttgg aggaataaag ataaatgaac cttcaattga
    13261 cttagggata gctatttctg tagcatctag ttttaggaat ataccaatag atgaagatat
    13321 agctgtcaca ggagaagtgg gtcttacagg agaagttaga gcagtaagct ttatagaaaa
    13381 gagaatagct gagtgtaaaa aacttggatt taaaaagata gtagttccta gaagtaatta
    13441 tgatgttata aaagatacca aaggcataga aatatggcca gtagataact taagacaagc
    13501 tataaatata gtgcttggga ggaatcaata aatatggaga attttctaga taataaaaat
    13561 atgctatatg cattaaaaat gatatctcct ggaactccac ttagattagg tctaaacaat
    13621 gtactaagag ctaagactgg tggattgatt gtaattgcaa cgaacgaaga tgtaatgaaa
    13681 atagtagatg gaggatttgc tataaatgca gaatattcac catcatatct atatgaatta
    13741 gctaaaatgg atggagctat agttttaagt ggtgatgtaa agaaaatatt atttgctaat
    13801 gcacaactta tacctgatta ttttatagaa acatcagaga caggaacaag gcatagaaca
    13861 gcagaaagag tagcaaagca aactggtgct atagtcatag ggatttcaca aagaagaaat
    13921 gttataacag tttatagagg aaatgagaag tatgtggtcg aagatatatc taagatattt
    13981 actaaggcaa atcaggctat acaaacttta gaaaaatata agacagtatt agaccaagct
    14041 ataacaaatt taaatgcctt agagtttaat gatttggtaa ctatttatga tgtcgcatta
    14101 gtcatgcaaa agatggaaat ggtaatgaga gttacaagta taattgaaaa atatgtgata
    14161 gaattgggtg atgaaggaac tttagtaagt atgcaattag aagaattaat gggtacgacc
    14221 agaatagacc agaaactaat attcaaagat tataataaag aaaatacaga aataaaagaa
    14281 cttatgaaaa aggtcaaaaa tttaaattca gaagaactaa tagaattggt caatatggca
    14341 aaactattag ggtatagtgg tttttcagaa agtatggata tgcctataaa aacaagaggc
    14401 tataggattc ttagtaaaat acatagacta ccaacagcaa taatagaaaa cttagtaaat
    14461 tattttgaaa actttcaaca aattttagat gcatctattg aagaattaga tgaagttgaa
    14521 ggaataggtg aaataagagc aacatatata aaaaatggac ttataaaaat gaaacaatta
    14581 gtattattag atagacacat atgatgaatt ttaaatgaat tttactactt ttttcttgaa
    14641 tataatatac actttggtct ataataaata agtataacta gggggtgaag cattgataag
    14701 gaaagtaaca agaatattgt ttattttact tggatttaca ataggtataa caacctattt
    14761 aacattaatg aaagattttg aaatattaac atttggaaaa gaaacatatg gttatatcgc
    14821 agctgtagta gcaggtataa taatagccat tttaggatat tttatagaac catgggttgt
    14881 aaataaagta aaagaaattg ctaaaatagt agataaagaa ttgtcaaaat atcctcagac
    14941 tgatatattg ttagggtcta tgggtcttat agtaggattt gttattgcat atttattaag
    15001 tggattagta aatagaatac caatagtagg tggaatacta tccttactat tatatttatt
    15061 cctaggatat cttggaatga aagttgcgct taaaagtaaa aatgatttat ttaatattgg
    15121 aaaactagga agattagcaa atcctattaa ggataaagat aaggataaag aaaataaaaa
    15181 agatataaaa gccattcctc caaaagtatt agatacaagt gtaataattg atggaagaat
    15241 agctgatatt tgtaagactg ggtttataga aggaaaactt attattcctg cttttgtttt
    15301 ggaggaacta agacacattg cagattcttc agatgattta aaaagagtaa gaggtagaag
    15361 aggtctggat atattaaata taattcagaa agaattaaat atagaagttg aaataagtga
    15421 gagagacttt gatgatatag cggaagttga tagtaaatta ttaaagcttg ctcaggtttt
    15481 aaatggaaaa gttgttacaa atgattataa cttaaataaa gttgctcaat tccaaggtgt
    15541 tgaagtatta aatataaatg agttagctaa tgctataaaa ccagttgcta taccaggtga
    15601 ggatatggtt gttcaagtgg ttaaagaagg aaaagaggct caacaaggtg ttgcatatct
    15661 agatgatgga actatgatag ttgttgatgg aggaagaaaa tatatgaatg agactataaa
    15721 agtacttgtt acttctgttc ttcaaactcc tgcaggtaga atgatatttg caaaacctaa
    15781 aaattaatat gttcaaagaa acctataatt tgggctgttt attttaaata gatggtccaa
    15841 atttatttat ttataacgat aatgtttaat gtattcttaa agatggggat ttaaatcaga
    15901 aagcagggag aatttatgag aaaaaagatt atatctttct tagcaacatt tatcataata
    15961 ttaacatcag caagtcagta tatttttgca gatgatatat caacacgtgg aaaagtaata
    16021 tttatagata tgaatagaac tagtatgagt aatatgttaa gaataaaatc attaagagaa
    16081 gaactagaca atagagggta tatcggtttg atgaatataa gaggcgataa aggaagtgat
    16141 gatagacggt catatgctag tatgggtgct ggtggtagag ctaatgtggc taatgaagaa
    16201 gatattaatt ttgaaagctc gagtaaggat agaaatatag tttttgaatc agctacagga
    16261 aagagcgcaa aaggtataaa taatttaact ataaataaat ctgtaaatga aaatttaaac
    16321 tttggagagt atggttctgt attagggtca ttaggacaaa gtttatctga taatggacta
    16381 aaagcatctg tattgggaaa ttcagatata attgaaaatg gccaacttat aaaaaataga
    16441 aacttatgtc taactgcaat ggatgaatat ggaagaatac ctaatggaaa tgtagatact
    16501 ataaataaaa aagacttatc tatgccttat ggaatatcaa ctgattatga taaattgatt
    16561 gtagagacca aagaagctta caaaaataat gatgtggttt ttgtggagct tggagataca
    16621 tatagattag atttatataa accaaattta aatgaaaaaa catatgaaaa tatgaaaaat
    16681 aaaatagaaa aaaatataga tgtatattta aaaaatatat tttctatggt tggagaaaat
    16741 gacactatct acatagcaag tgcatttcca agtgatttag attataaaaa taaaagaaga
    16801 ctttctccaa tagtaaaatt aaatggagta gggaaaggtc tattatcatc ttcaactact
    16861 agaagagaag gtattgtaac aaatttagat gttggggttg aaatattaga caactttaat
    16921 ataaaaaatc aaaatatggt tggaagaaaa tatgaactta ttaacagaga tgataataaa
    16981 gaatttttga tggatgaata tcaaaagata gtatctatct caagcataag gtctacaatt
    17041 ctgaatggtt ttgtaagcat agttttcttg tcatggatag ttgctatgat tgcaatttta
    17101 tttagaaagc atatatcaaa aaaatataaa gaaacaacat tttttatatt aaaggaactt
    17161 ttaaaaatag gaatagtaat gccactgtca tttatgataa caccaataat gaatttcaaa
    17221 acaccattag caatatcttt aggaataatt ataataacac ttactatata tcttataagt
    17281 aaagttttaa taaagaatga tttaaaaaac atgctgtttt ttactggatt aactatagta
    17341 attatggtta ttgatgctgg atttggctca tatttaatga aaagcaatgt tatgagttat
    17401 gactgtataa ttggagctag atattatgga gtaggaaatg agtatcaagg tgtggcaatt
    17461 ggtagtgcaa tatttacatt tgcaatttta cttacatata aaaacatacc aaagtggtct
    17521 gtaatagttt tttctttgct tatcttaatt acaagtgcat ctccaattat gggagcaaat
    17581 gttggaagtg ctatttctga atgtgttgca tttttactat ttatactatt aatatataat
    17641 gtgaagatag acttcaaaaa aattgtatta ttaggtatag cagtattatt tgtattagga
    17701 gcttttgtag caatagatat gattttggga agtaattcac atttaggtat gtttgtaaaa
    17761 gaaatttact ttaatggacc aggagagata atacaaacat ttagtagaaa gatagagatg
    17821 aatttaaagc tagctcaaac cagtgcatgg gtaaatatac tgttaactgg aataggggta
    17881 attttagctc ttatgattaa tcagattaga tactttaagc aacttatgga tgagtatcca
    17941 attgtattta aagggtttat agcatcaata gcgggatgtt tagtaactct tttagtaaat
    18001 gattctggga ttgtgtcatc agctacagcc tttatttata taattgtacc tatgataaca
    18061 ttaagtgtaa atctcacagc attaaaagaa taagcactat atgagcacta tgtaaatatg
    18121 aacacattaa tttaacttcc ttctttattt tataaagaag gaagttaata aaaaataaat
    18181 tataataaaa aagagtttat ctcaaaattg atttttctaa tcaaattttg gggtaaactt
    18241 tttttattat aaaggcaaat aacatataat cttatatttt aggtagattt tttcttatat
    18301 gtttaggggt acatttaaat ttttctttaa aaatcctata aaataatttt gtattagtaa
    18361 atccatgagt ttctaatata ctgcataagg tatcatttgt attaattaag tctttataaa
    18421 tatgagaaat acgtacatca tttaaatact ctaagtaagt ttgccccata tattgtttaa
    18481 attttctaca aaaatattct ggttgtaagt gtgccacctt agcaattttg ttaatagaaa
    18541 taggagattt gtaattaata tttgtatatt ctaaaactgg ttcaaatttt gacaaatcaa
    18601 gtactgtttt tttcatattt ttattaccta cagatatttt aaagtttgta tataattcaa
    18661 ataaaagttc aaataataag cttgtaaatt gcagattagc tgctggagga gaactaagtt
    18721 taatttctct catgttttct aatataagtt taactttact tgaatttctt ttatagttat
    18781 tgtcattagc attaacctta aaatcaaagt agcaattttt aaaatcagga atgtatttgt
    18841 ttagaaaaga cattggtact tgcaataata tagaggtatt atgataagta catctagttg
    18901 agtgaataat tccagaatta atgaacatac actcgttagc ttttaagtta taagtgtaac
    18961 cttccatgtt aatttgtaaa tcaccagagg ttatataaat tatttctaat gagttatgcc
    19021 aatgatttgc tacataacta ccactatcat caaatagttt aaaattaaca tctaaattat
    19081 caataggttc aattatttca tgtgaaaaac tatttctgtt cataataatc tcctccttat
    19141 aactttaaat tataactagt aaatttataa tattcaatat taaaaagata atatagacta
    19201 ataaattaga caataaacat acttaagaaa acagataaaa tcaaatataa taactgtata
    19261 tttaaataat ttaaaaaaat tattttagta taagtgtaaa atatacctat ttaaataaga
    19321 taagagggga ggactttatg tgtatataaa aggtgtaaac ttaggaggtt ggttagtttt
    19381 agaaaaatgg atgaccccaa gtttatttga aggtacagaa gccgaagatg aatactactt
    19441 accaagacaa ctttcaagag atgtatatga atctaaaatt aagactcatc gtagtgaata
    19501 catcacagag agagattttg caataattaa atctatggga tttaattcag ttcgtatacc
    19561 agtaccatat tttatttttg gagattgtga accctttata ggttgtgtta aagaacttga
    19621 taaagcattt tattgggcag ataagtatgg acttagtata ttgatagatt tacatacagt
    19681 tccaggaagc caaaatggat ttgataatgg aggaatatca ggggtatgta gctggtcaca
    19741 aaacccagaa tatgtagagt ttacattaaa tgtactagaa agacttgcaa aacgttatgg
    19801 gatgagacgt gaattgtatg gaatccaaat tttaaatgaa cccataacag aaagaatgtg
    19861 gaatataatg aatgttccaa atcgatttaa ggctgtagat aaggatatgg caagaagaag
    19921 taaacctaat tcattagaat ttttacgtga tttttatata aaagcatata aagtaatgcg
    19981 tccttatatg agtgaggaaa acgttatagt atttcatgat gcatttgaat taaaatcatg
    20041 gaaagacttt atgaaagagg aagaatttaa aaatgttgtt ctagatacac accaatattt
    20101 gatgttagct gaagcagatg gatgtgaaca aagtattgat agttatctca aatatattag
    20161 agataattat gctaaagata ttttacaaat gcaaaagtat tttcctgtta tatgtggaga
    20221 atggagctta tttaattcat atgcttgtgg tatagataca gctggaggtc aatcgcctct
    20281 aaatgggatt gaatcaaata tagataaatt atcaaaagat gaaagaagag aattatatag
    20341 gaagatagca aaagcacaga ttgatgcatg gagaaatgga agtggtcact attattggaa
    20401 ctataagtta ttactagata cagttaatga agaaggctgg ataggttggg atagttggga
    20461 cctaggcaaa tgtgtagctc aagaatggta tcctatagaa tattaaacta aaattggagg
    20521 aaaagatatg attaaaaacc ctatacttcc aggctttaat ccagatcctt gtatttgtag
    20581 aaagggagat gattattatc ttgtagtttc atcttttgaa tggtttccag gtatacctgt
    20641 ttatcactct aaagatttaa aaaattggga gctatacact catattttaa cagatgaaac
    20701 aaaaatagat ttaaagaagc ttccttcatc taaaggaatt tgggcacctt gtttgactta
    20761 ttgtgaagaa gaagatttat tttacatagt ttttggaatt atgaactcta tgaatgcaag
    20821 atattttgat gttgataact atttaattac atcaaaagat ataaagggag agtggagtga
    20881 accagtatat ctacattcat caggttttga tgcgtctatt tttcatgatg ataatggtaa
    20941 aaagtggatt tcgtcattag actgggagac tagagaagga tatgaaaaac ctggtgttat
    21001 atgtttagta gaatactgta tagaaaaaaa agaaatagta ggatatccaa agagaatatg
    21061 gtcaggagga actgatagag gttgtattga ggcaccacat ataaccaagc gtggagatta
    21121 ttattatata atgtgtgcag aaggtggaac tggatatggt catggtgtaa ctatgggaag
    21181 atctaaaaat atatggggac cttatgaaaa agatttaatg aatccaattg taacttcaat
    21241 tccaggagat ttttatgaaa ggcatgaccc tgaccatcta aagcctaaat actataatcc
    21301 agaatcaaag cttcagaaat ctggtcatgg aagctatata gaaacaccat caggtgaagt
    21361 gtatttagtt catctcacat ctagaccatt tgtaccagag ttaaggtgta ctttaggtag
    21421 agaaacagct attcaaaaaa tgaaatggac agaggataat tggcttcgaa tggaagatgg
    21481 aagtaatttg gcaaaagaat atgtatcaga aagtaagcta gaagagcatt tagtttcatc
    21541 tataccaagt tttgatgact ttgattcaaa taaattaggt ttacaatact atgcccctag
    21601 gatttcgcca ttatcatttg cagatgttaa ttctagaaca ggatatgtaa ggattagagg
    21661 gcaagaatca agaacatcat taaatagagt gagcatatta gcaagaaagt tgacttcagt
    21721 atatgcaaga ataactacta aaatggagtt ttatccagag gtacatcagc atagcgcagg
    21781 tttgataatg tattatgata atatgaatta tataaattta agaaagtact atagtgaaac
    21841 attgggtcaa agtgcactat caataataca tcttgaaaat ggagagaaaa cagagttttt
    21901 aaatactagg ataccaataa aagatatacc aatatatctt cgtctgtata taaaaggtcg
    21961 taagtcgtat ttcgaatgga gttatgatgg agaaaagtac caaagaatag gagagacatt
    22021 tgatacaact aagttttcag atgagtactg taaatatgga gaatttacag gtacatttat
    22081 aggattaact tgtgcagatc gtgtaaagca taaacactat gctgattttg atttctttga
    22141 atatatagca gacgaatcaa aagatgtaga ttaataaaat tattactaaa atttttagag
    22201 cataaggtaa aacttatgct ctgaaataag aaacattaga aggtaaatct tacaagaagg
    22261 agtatggtat tatgaataaa gaggttaatg ttaaagcaac tactattaaa tatgaaaaga
    22321 tttcattttt tgaaagagtt tcttatgggt gtggggattt aggatgcaat atcatatatt
    22381 cagcaatgtc agcattttta ttgttttatt acactaatta tgcagatgtt agtgcagctg
    22441 ctgtaggtag tattatgctt atatctagga tattggatgg gtttagtgac ttgacaatgg
    22501 gaattatagt ggatagaact aaatctaaat atggtaaggc taggccttgg attttaagaa
    22561 tggcgattcc ttttgccata tcagcaatat tattattttc tgttccatca agtcttggtg
    22621 tcacttctaa attaatttat atttttatta catataactt agtttctact gttatttata
    22681 cagcaatcaa tgtgccctat gcaactctaa attcacttat aactcaagac cagtatgaaa
    22741 gaggagtatt aagtatattt agaatgatat tagccacttg tggtacttta ataataaatg
    22801 gacttacatt acctctagtt gagcattttg gaaataattt atcagcatgg actaaaacgt
    22861 tttttatatt tggaatagca tctataatag tattttttat aacatttact ggaactaagg
    22921 aaagagtaaa agcagttaag caaaataaga atgaagtaat accatttaaa atcggtatta
    22981 aatctttatt tagaaataag tactggatac aaataacatt atgtttagtt tgtatattta
    23041 ttgtatttgc aataaatggt ggttcatctg tatattatgc aaagtttatt ttaggagatg
    23101 aaaaattatt tgctcctata aacatggttt caaacgtatc tcaaattata gctatgttta
    23161 tggttgctcc ttttataaaa aaatttggga aaagaaatgt attaatagta ggttcaataa
    23221 tattaatatc atcaaatgtt atgtttataa tagctggaca aaactatatt ggagtaatat
    23281 ctgcaagtgc tataaaggga atagggagtg ctggaatagc agcaacgatg tttgctattg
    23341 tttcagatac tattgaatat ggagaatgga agactggata tagaactgaa ggtcttataa
    23401 atagtgcatc tagttttggg tttaaagtcg gaaatggact aggttcagca atattaggtg
    23461 gagtattatc aattggtggt tatgtaggga catcagctac tcaaagtaat tcagctatag
    23521 tatcaataaa agcatgtttt atatacctac ctatatttat aaccatatta caaattataa
    23581 taatgttttt ttataagctt gacaaagaat atagtactat acttaatgaa ttaaatacta
    23641 aataataaaa tattttctat tcagtcttag atttaattaa ggattattat agtttattat
    23701 ttatgaaaaa ctattatata ttcatgatat attaaagcgt ttttagaaaa ataaaaaaga
    23761 aaaactaata ctaaaaatat aaatatatcc agtaaaaaac atcttaaaat ctatttattt
    23821 ggattctaaa agaataaagg agatacctta aaataaaaat ttgagttacc tcctttttta
    23881 ggcaataatt taaggtttat gttgtttcaa catgatttga aatgatgtac cctttcccat
    23941 aatgcttgaa actgaaatat ttccttcatg tgcatcaata atttgcttaa caataaataa
    24001 tcctaacccc ttattttgag tattttggtt tttgctacta taatacttag caaaaatatc
    24061 atttaatgtt tctggattta tcccaatacc attatcatta atattaatgt aaatttcatc
    24121 agatttttgt gttaagacaa catctatttc tgttccagaa ggattgtgtt caacacaatt
    24181 aattaaaagg ttataaatag ctctatacat tagtgtctca tcaataacca aatttaaatg
    24241 ttgtaaatcc gtatgaaatt caaatatatg tttttctgat ttcgggttat tggttatatc
    24301 agcaataagg tttcgaagaa aagaaactat ttcaacttgt gtgtgtttaa gatgtatttt
    24361 gttatgtgaa tctataaaaa acgtcagact taactcatct attaattttt caatatatat
    24421 tccctttgta tatatattat ttaaaaaggt taacatctct tcttcactaa aactgtggtt
    24481 tttgttaagc attagagatg aatatccagt gatatatgac aagggggttt ttaaatcatg
    24541 cgacacacta gcaagccaat cagtttttgc aacttcaagt ttttctcgtt caatctcagt
    24601 ttcttgaagc ttgttgccta agtcttttat atttataata acttctctgt acataaagtt
    24661 ataccatttt agctttccat ttttagtaaa agctttttca gatattgtat agtttcctct
    24721 agataagttg cttattgaac taattatcag gtagagtggt cgaacaagaa ataaacaaaa
    24781 tagtattcct cctgtaataa agcaaaaagt aaatataagt gtgcttggga aatagataat
    24841 agacgaatca attacatata aaaatttatg tgaatcttca gggtatatta attgattaag
    24901 caatatgaat aatgttatga agtatactag gaatataaag agacctgttg taaagtaagc
    24961 aatgaaacga aaatataatt ttttcaatat atcagttccc ctttggcggt atgaatttat
    25021 acccaattcc acgaaggttt gtaataacct tgtatggttt attgtcatcc agtatctttt
    25081 ttctaagttt ggatatatgt attgtaactg tcttttcatc gccatatcct tgtaatcccc
    25141 aaattttatc atacaggtgt gatgtagtaa agaccctatt tggattttga caaaaaaatt
    25201 ctagtagttc taattctttg gctgtacatt ctacattttt accacttaca gtaagtagtg
    25261 catgagccat atcaagaaca atatatccat aattataaac taaaatattt tctgagtgat
    25321 tacataatac agaacgttcg agttgttgac gtctaaaaat agctttgatt ctagcaacaa
    25381 gttccattgt attaaatggt tttgtaatat aatcgtcacc accaatagca agtcctgata
    25441 atttatcata atcactagct cttgcagtta gaaaaatgat aggtgctata gtttttttgc
    25501 gaaaatttgt acataagtca aatccactat aatctggtag cattacatca agaatgataa
    25561 ggtcatattg attattttct atacattcaa gggctttggc ccctgttgat acacaggtaa
    25621 tattattgta ttgctcttta tttaaggtta ttttcaatag tgttaaaagt ccttcttcat
    25681 cgtcaacaat aagtattctt tcagagtttt taaatttgtc attcataata attcatctcc
    25741 cagtatacaa aaatagtatc attataatac catacatgca aagtgtaagc aataaattat
    25801 tcttttgatt ttactttaac tttactttta ttttactttt gtactgtatc ttatagataa
    25861 caagaaagaa aaaaataaaa ataggaggta aaaatgataa aatcactgaa atcaagagga
    25921 ataagtattc tattatgtgg agctttgatt gttggtgtaa tgacaggatg tacatctaaa
    25981 gctacatccc caaaaagctc aacacctaaa tcaactccta aaacagtaga aaaagttaca
    26041 cgtgcaaatt gtgaaaaaca actaaaggaa gtaaaagcaa agtataagaa aaatccaaat
    26101 gatgaagcta tcagattaga atatgctcaa atactcttta agttgggaaa tattacagaa
    26161 gcacaagaaa ttctgaatcc gttactaaat tcaaagaagc cttcaccaga tgctattttt
    26221 ctttctgcac gaatagaata tctgaatggt aattatactc aggctgaaaa actatatgat
    26281 aatcttatag agcaatatcc tgataaattc aaatcgaagg ctgaagacga gttggcactt
    26341 acgtattatc aaacaaatca atatcaaaaa gctgacaagt tatcctccgt gaaaacaaat
    26401 aatgctctat tggaaatgat gaaagctttt aaggataaac atccaaataa gattgactgg
    26461 aatggaaaaa aagaaactgt aattccattt gtaacaggtg acccactacc tattatacct
    26521 atggaaataa atggtaaaag aataaataca attattgata atggtgctcc aatgtttgtt
    26581 gttgatgaga aaattgcaga agaaattggt attaatctag cttcaaaaga ggaaaatact
    26641 aaatttgctg gtggtaatag tattggaatt aattttggtc aagccaattc acttaccata
    26701 ggagatgtaa acatggagaa tattcctgta atgttaggac catttgatgg atttgaaaag
    26761 ctgtttaaag actatggaaa tgttcatgga ataatgggaa caactgtatt aaaggagttt
    26821 gtacctacaa tggactatcc tagtgggcag ctaatattaa gacctagaaa tgaagtaggc
    26881 agagataatc ttaataagat gcttacaaat gataaaatat tagaagaagt tccatttaca
    26941 cttgcttcta ctcattttat gtttggaaaa ggttcaatca atcaaaaggt tgggttaaat
    27001 ttctttgttg attcaggtct tggtgacgaa aaaggagcag gaattgtatt aactgaggaa
    27061 ataatgaatt ccttgaaaat tcctatgcct gagctaaaga aagcagagga aggaaaaggt
    27121 ggaatggctg gaagtgatta taaagaagga tatttcaatc tttcatctta tggtctagga
    27181 gatttgcaac ttaaaaacgt ccttggatat tattttacag gtgatacgtt ggattatgat
    27241 gaggggattg gatttgttag agatggattg ataagtcatc actatttaaa gaactataaa
    27301 tggtctattg actttgattc tatgaagatg acatttagta agtaaagata gtatataata
    27361 tgaattaagt gggaaagttt caactgttca aggaaacggt gatacaagaa aagtatcacc
    27421 gtttttttta ttatacaaaa aacagttgac tttttatatg aacccctcct ataatgttac
    27481 tgaaattaag taaaatgatt gaacaaatgt aaagataatt gaaaaagctt gattttggag
    27541 ggaagcaaat gaaaaaaatt ggagacttaa gattaatgat gaagtgttgt tcactttatt
    27601 atgaagataa tttgaatcag caggaaatag caaatcaatt gggaatatca agaccaacaa
    27661 tatcaagaat attaaaagaa gcttttgaac aagggatagt aaaaatacag atagttgatg
    27721 ttttgaaaaa tgattaccaa aaaatagaga gaagtttgga gagaaaatat aaattaaaag
    27781 aagtaatagt agtagatgat aaacaggatt cactaacaca aaaacaagaa ttagcaagag
    27841 ctgtatctga atatttaacc agggtagtaa aggaaaatga tataataggt gtttcaatag
    27901 gaacaacact aaaagaaata ccaagatatg tggaaaaaag taactgtaaa aatgttacat
    27961 ttatacctct attaggaggg attggagaca atgaaataga tattcatgca aatcaaatag
    28021 cagtaagttt agcaagggcc tttggaggtg attttaaatt attacatgct ccagctgtta
    28081 tgtctgactt atctacaaaa gagaaacttt gcaaagacga aaaaattaaa gaagtactag
    28141 atttaataga taaaacaact atagcaattg tgggtatagg aaatcctatg agtttaaact
    28201 caaccataat ggcttctgga tatatgaatg aagcagatat agaagattta aaaaaataca
    28261 actcaatagg tgcaatttgt ttgcaagctt ttgataaaga agggaaaact tctatacttg
    28321 aatttaatca aagagtatta ggagtaaaac tggaagattt aaaaaagata aaaagaacaa
    28381 taggtgtcgc ttcaggagat gaaaaaatag aggcaataaa ggcatcatta aaagcgaaat
    28441 ttataaatag tttagcaatt aatcacagtt tagcacttaa attattagaa gattgtgact
    28501 aatagaaaga tagataaaag ttaacaggag ggaatatata tgtcaatatc aaaagaaaca
    28561 ttgcttgaaa tgtataagag aatgaatcag gctagaaaat ttgaagagaa agttagttgg
    28621 ttttttgcaa gaggtatggt acatggaaca actcacttat ctgtaggtca agaagcatca
    28681 agtgtggcag ctgtaatggc tttagaaaaa ggagatttag tatcattaac tcatagaggt
    28741 catagtcaat ttataggaat ggggatagac ctaaataaaa tgatggctga actaatgggt
    28801 aaagaaactg gcttttgtaa gggaaaagga ggctcaatgc atatagcaga tattgagtca
    28861 ggtaacttag gagcaaatgg agttgtaggt ggaggtctta caatagcacc aggggctgca
    28921 cttacacaac agtataaaaa aacaggcaaa atagttttat gtagttttgg tgatggggca
    28981 tcaaatgaag gtacttttca tgaaggaata aatttatcat caatatggaa attaccaata
    29041 atattttact gtgaaaataa tttatatggt atgtcaacaa gtataaaacg tcatatgaat
    29101 atagaaagta ttgcaactag agcagcttct tatggaatag aggggatatc aatagatgga
    29161 tataacccaa tagaggtata tgaaacagta caaaaagctg ctgaaaagtg tagaagagga
    29221 gaagggcctg tattaattga aagtaggact tatagatggc taggtcattc aaaatcagat
    29281 gcaaatgtgt atagaacaaa agaagaaata gagtcatgga aagcaaagga ccctattgaa
    29341 tttttaagaa attatcttat agaaaataat ttatctaatg aagatgaatt agataagatt
    29401 caagaatttg caaaacaatc aatagaagat gcagtagagt ttgctcaaaa tagcccaaat
    29461 ccaaaaatag agtctttatt agaggatgta tatgcagact aagaatagta aaggaggaaa
    29521 ataaaaatga gtacaaggga attaacatat gcacaagcaa taaaggaagc aatgtcagaa
    29581 gaaatgagaa gagatgaaaa tgtaatattt atgggagaag atataggaat atatggagga
    29641 gcatttggcg tatcagttgg tatgatagat gaatttggac cagaaagagt gagggatact
    29701 cctatatcag aagcagctat agcaggagcg gcagcaggag cagcagcgac tggtttaaga
    29761 cctattatgg aagtaatgtt tatggacttt gtaacaattt ctatggacgc aattgtaaat
    29821 caggcagcaa aaatgagata tatgtttgga ggaaaagctc aagttccaat ggttgttaga
    29881 tgtccaggtg gttctggaac tggttcagca gagcaacatt cacaaagttt agaagcttgg
    29941 ttttgccatg taccaggagt aaaagtagtt gcaccttcta ccccagcaga tgctaaggga
    30001 ttgttgaaag cagcgataag agataataat ccagtcatat ttgttgagaa taaattgtta
    30061 tacagaaaaa aaggtgttgt gccagaagat gattatgtaa ttgaaattgg aaaggcagat
    30121 ataaaaaaag agggtactga tgttacagta atcacatatg gaagaatgtt acaaagtgtt
    30181 gaagaagcag cagagaatct atcaaaagaa aatataaacg ttgaaattat agatttaaga
    30241 actttatacc cattagataa agagactata gtgaaaagtg tatgtaaaac tggaagagtt
    30301 ttaatttgtc atgaagcagc taagactggt gggttaggtg gagaaatatc agccttgata
    30361 acagaaagtg aatcatttga ttatttagat gctccagtaa aaagaatttg tggaaaagat
    30421 gtgccaatac catataatcc agagttagaa aaagcagttg tcccaagagt tgatgaaata
    30481 gaagaagcaa taaaatcttt aattgttaga taaggaggga tagatatggt ggcaaataaa
    30541 gtaaaagcca caccagcagc tagaaatcag gcaagaaaag acaatataaa attagatagg
    30601 ctgattggaa gtggagagaa tggaaggatt catttagtgg atgtgttaaa ttatttaaaa
    30661 gataacaaag caaatactac tcctttagct agaagaatag cagaagattt aaatatagat
    30721 ttagaaacta ttgtaggtac tggatataat ggaaagataa gaaagtgtga tgtggaaaaa
    30781 ttaactgaaa aagaaactat tgtatcaact aatacgtcta aatttagtga gaaaaaagag
    30841 acaaagattg aaaatgaaaa ttcaagtatg tttaatacag tagaaggagt atttgaaaaa
    30901 ccaaatccaa tgagagccac tgtagcaaga cgaatgtcag aaagttattt tagtgctcct
    30961 gtatttacat tcaatataga agtagacgct acagaattga aggcacttag agtaaagtta
    31021 atagacacag taaaagaatc aactggagta aaattaacta tgacagattt aatagtaatg
    31081 gcagtatcta gaatacttcc aaatcatcaa gcattaaact cagcatggac agatgagggt
    31141 atatttagat ataaagatat aaatatagcc attgcagttg gtctagatga aggtttatat
    31201 gttccagtag taaaaagtgt aaacaaaaag tctttaaaag aaatagcaaa agaaagcaaa
    31261 gaacttgccg aaaaagtaaa gacagggaaa cttatgccag cagaccaaga aggtaataca
    31321 tttacaataa gtaatgtcgg aatgtatggt ataactacat ttacacctat aataaatatg
    31381 ccttcaagtg caattttagg ggtaggtgct acacaagata agtttgttcc agtaaatgga
    31441 gaggctaaaa taaaacctat aatgaactta tcattgacat cagaccacag agtaatagat
    31501 ggaacagtag ccgcaaaatt cttaaaagat ttaaaagaat tgttagaaaa tcccttatca
    31561 atgcttgtat aggttttgac atttcgttac tgatataaat agtttgaata gattatatta
    31621 ttataattat ctcagtaaat ttaaaacttt tatatattga gaattatttt taaaggtaac
    31681 tgtatatgaa tatgatttgc ttaattaaaa tatatgaaaa taaataggag gagagcctat
    31741 gtcagtagaa gtaataatgc caaaagcagg tgtagccatg gaagaaggta ctatagtatc
    31801 ttggctaaag caagaaggcg aagaagtaaa gattggagaa cctatattag aaataacaac
    31861 agataaagtc aatatggaga tagagtcaga aggagaaggt acacttgctg caatcataca
    31921 taaagaggaa ggtgaagtat taccagtatt tacagtaata ggtgtaatag cagaaaaagg
    31981 agaaaatcaa gaggaagtaa aagctaaata tttatctgga aatgtttcaa aagaagatat
    32041 agttgaagag aatcaaaaca tagaagctaa agaagaaaaa ataaacaaaa aagagtgtaa
    32101 tcatgattat gatgtagtgg taataggtgg aggacctggg ggatatttat cagcattaaa
    32161 agcagctctt ttaggtggaa gagttgcttt agttgaagaa aatatactag gaggtacttg
    32221 tttaaataga ggttgtatcc ctacaaagac ttatataaaa acggcagaaa tattagaaga
    32281 aattgaccag ttatcaaaga gaggcgtaaa agtaactgta gataaagaac aggacattaa
    32341 gaaggctata aaatataaaa atagagtagt taaaaaactt acagctggtg ttggtggact
    32401 attaaaaagt agagatgtag aggtgtttaa tcttaaagct agtgttaagg aagagcataa
    32461 agtaatttta tcagatggaa aagttttaga tacagaaaat ataataattg ctacaggttc
    32521 taaggtaaga atattaccta taaaaggaat agaatcaaat ttaataataa ctagtacaga
    32581 agctttagat ttagaaacag taccagaaga attagtaata attggtggtg gagtgattgg
    32641 ttgtgaattt gcagagatat tcaattcaag aggctctaaa gtaactatag tagaaatgga
    32701 agatagagta attccaaaaa tggataaaga tttaagtgaa tctttaaaat attctcttgg
    32761 taaaaaaggt ataaacgtgc taactaaaaa gaaagtttct gaatttaaag aagaaggaaa
    32821 taacatatta gtgtgtattg aagatgaaga accaataaaa gcagatttat gtctatatgc
    32881 tataggaaga gaagctaatc tttctggtat agaggactta gatattaaaa tagataaagg
    32941 ttcaatagtt gtaaatagca aaatggaaac aagtatacca agcatatatg cagtaggtga
    33001 tgtgactgga ggtgtaatgt tagctcatgc agcttttaaa atgggagagg tagcagcttc
    33061 aaatgctcta ggtatgaata aagaagttga tttaggtgca ttacctagtt gtgtttatac
    33121 aattccagaa gtagcatcag ttggtattac agaagaggat gctagaaaaa aatataatgt
    33181 aaaagttggt aagtttaatt ttgctggaaa tggaagagcc ttagcttctg gtcaagaaca
    33241 aggatatgtg aaagtagtag cagatgctaa atatggagaa attttaggta tacatatgtt
    33301 tggatgtggt gtagcagaac ttataaatca tgcagcatca ttcaaagcat tagagatacc
    33361 tgctgatgaa gctagtgagt taatttttgg tcatccatgc acttcagaag ctttgatgga
    33421 ggctttagca gatgtaaatg gagaatgttt acacttacct aaaaaataaa ttgttaatgt
    33481 aagtctatta ttaatgttaa tttatatcat aaagttttaa aagaattact tagccatacc
    33541 ctttgttgta caaataaatt atttgcacaa caaagggtat tttttatgga aaaatatata
    33601 gtatgaaacc tttgtagttt ttgttataca aaaaagatag taatataaaa taacagtatt
    33661 attttagaat gatttcaatt gtaattagaa aaaatgattt ttttgttttt aagaaaagta
    33721 ttatttgtaa aatgtaaaaa aaattttctt aatatttcaa taaaagaata gcttgattta
    33781 aatgttatta ctttataaaa aaataataag cacaaaaaaa acaatatatg gcatataagt
    33841 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
    33901 tgaaaatgaa gataaaaaaa atcctttaac agatgaagcg atttcaagta tgttaaatat
    33961 tcgaagagaa gatgttacct ttttaagaaa tgagttaaaa atagaagatt caaggcaaag
    34021 aagaaaagtt gttttaatta aagctataaa agacatttta aaagaagaaa aaactataaa
    34081 taaaaatgat ataacaagaa gattaaacag cattggtttt acagtatcaa gatttacagt
    34141 tatacagtac ttaaaagagc ttcaagattc tgataactta aaactttata aagaaagtga
    34201 tgataaaaaa gaagaaataa acaataatag agaaaacaca gatatagcat ttgataaact
    34261 cataggtagt agtggtagct taagtacaat tataaaacta gctaaagcag caattctata
    34321 tccacctcat ggtcttcata ctatcattat gggaccaact ggtgttggaa agagtgagtt
    34381 agcagagtgt atgtataaat ttgcactaga atcatccaga ttccctaaga atgcaccatt
    34441 tatagttttt aatgcagcag attattcaga gaatccacag cttttgttat cacagttatt
    34501 tggacatgtt aaaggtgctt ttacaggagc tgacgagagt aaagaaggat tagtatcaaa
    34561 ggcagatgga ggaatactgt ttatagatga aatacataga ttacctcatg aaggtcaaga
    34621 aatactattt caattgattg ataaggggat ggtcagaaaa ttaggagaaa caaaactaac
    34681 aaataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
    34741 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
    34801 attaaatgag aggtttgata ttataaataa tttcttctta atagaagctc aaagaatggg
    34861 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg actgtatagg
    34921 taatgttggt caactgagaa gtgatattca agtagcttgt gctaggggac tactaaatca
    34981 acttacaaat aaacaaaaag aagtaaacat aagcatatca gatgtacctg gatatgttaa
    35041 acaaggtctt ataaaaatca gaaattgcag aggtaaaata gaaaattatg tagatggaga
    35101 cttaattata gactcaaatc ttcaaggtga aatagaaaag aaaaatgaag acatatatac
    35161 ttttccagat gaaatatata aacttactga aagaagacat attgatttat tggaacaagg
    35221 tttagatttt gatgttataa atagaatcgt tggaggagaa ttagaaagtt gcattcaaaa
    35281 atacataaag caagttaaaa aagtttctat tagtaataat cttccagata taagtccgat
    35341 tgttggaaaa tatatagtag agctaactta tgaagtaatc aaaatagcat cacaatatct
    35401 taattcatta gaaccaaatc tacatttatg tttagcagta cacttaaaag ccgcttttga
    35461 gagattaaaa gaagggaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
    35521 tccactagaa tattctgtag cagaaaaggt ggctcaatat ctaaaggaaa gatataacat
    35581 aaatttgcca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagcagaag
    35641 aaatatatct gaacaaaaaa agataggtgt acttcttatg gctcatggaa gggtagcatc
    35701 ttctgtatgt gaggttacaa ataaactatt aggaattaat catgcaaggt atttagatat
    35761 gccatttgag aagaaaccag aagaaatgat tgaagaagct attacaataa taaaagatat
    35821 tgatgaaggt agaggtgtaa ttatactagt agatatgggt tcactttcat attttggaga
    35881 tattatttct ggaaagactg ggattgatat aagaacaata tctagatttg atacattgct
    35941 ttctatagaa gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
    36001 tgaagttaaa ggtatagagc cacaagtaaa agaaaaagtt agtaaatata acaatacaaa
    36061 agtaaatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
    36121 taagataaaa aaaatcctag aggaaaatat taaaagtata actgaaaagg ttgatataga
    36181 gcctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagtaatga
    36241 taaaaatgta attgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
    36301 tagcctagta gatataaatg ataaagtaaa gttaaatcaa ataaacaatc taattgatac
    36361 aaatcaaatt agtgagacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
    36421 tatattcgta gatttacaag ttaaatccaa agaagaagtt ctaaaatata tgagtaaaaa
    36481 acttagagag aaaggttacg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
    36541 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
    36601 aattagacca gctataagca tagctatttt aaagaatcct attgtgtgga gtaaaaataa
    36661 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
    36721 actttcattt atagaaacag atgaatttaa gcagataaaa aacataaaag atagagattt
    36781 tattagggag atgatattag atggagtcaa tgaaaataat tagtagtaat ttaattttta
    36841 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttatttg
    36901 atgaacagta tgtaaaggca agttacatac aagctgttat agcaagagag aaaaagtatg
    36961 ctacaggatt accaacagaa atatatggag tggcaatacc acatacagat atagtacatg
    37021 taaatgagcc aggaatagca attgggatac tgaataaacc tgtaaaattt ataatgatgg
    37081 gtacagatga tacagagatt gatgtaaaag ttgtatttat gttagccgtg aaagagccac
    37141 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
    37201 ataatattgt tgacttaagc gaagaaagtg tgagtgattt attaaactct aaattgaaaa
    37261 attgaatata taaagtatat taaaaaataa aaatgttatt gaagatttct aactataggt
    37321 atctttaaaa taaaataatt tcaatggggg tgactaatgt gactaaaaag atattagttg
    37381 catgtggaac aggagtatgt acttcaacaa ttgctataaa caaattaaag aaagcgcttc
    37441 aagatattgg taaattggat atggttaata ttacacaatg taaagtggta gaagttgcat
    37501 caaaagcacc tgattatgat ttaataattt gtactacaca agtatctagt agtataaaaa
    37561 caccagtgat aaatggatta ccttttttaa ctggtgtcgg aatggataaa ttaatcaagg
    37621 atgtattaga aaagctagaa ttataatcaa aaaaattaag gaacatggtc tctaaaatta
    37681 taagttttag agacttaaaa ttaaataatg gagggtcttt atatggagat attaaatttc
    37741 attgttggtc taggcgcaca agtaatgatg ccgataataa tatgtatttt tggtttgata
    37801 ttaggtacaa aactaggaaa atctttaaga gctggtttaa ctgtaggagt tgggtttata
    37861 ggtcttaata ctattatagc tttgctaaca gataatttag gtccagctac acaacaaatg
    37921 gttaagaatt taggactaag tttatccata atagatgtag gatggccagc agcatcggcc
    37981 atagcttttg catcaacagt aggggcttta attattccaa taggtcttgt ggtaaatata
    38041 attatgttaa ttactaatac cactcaaact gttgatgtag atatatggga ctactggcat
    38101 tttgctttta caggagcttt agtggcaggg gctactcaaa gtgtaatgtg gggagtattt
    38161 gcagcagtag caaatatgat aattgtattg gtaatggcag atttaactgc tccagggata
    38221 gaggaatatt taggtatgcc aggtatatct cttcctcatg gatttacaca agcatttgtt
    38281 ccaattgcta tagtagtaaa taaattatta gacctaatac caggcataaa taagattgag
    38341 ataaatgctg atacattgca gaaaaagttt ggattatttg gagaaccttt aataatgggg
    38401 tctgtaatag gggtaataat tggtgttgca gcgaaatatg atataaaagg aatattacaa
    38461 ttaggtgtaa ctatgggagc agtattaata ttaattccaa agatggcagc gttattaatg
    38521 gaaggattat taccagtatc agaatctgca caggaattta ttgaaaagag atttaaaaat
    38581 agaggtaaga tttacatagg cttagattca gcagtaggaa taggtcatcc tgttacacta
    38641 tcagttgcat tagtgttggt tcctttgact atacttatag cagctatatt gccaggaaat
    38701 aaagttttgc catttgcaga tttagcagta attccatttg cacttgtatt aattgtgcca
    38761 attacaaagg gaaatgtgtt tagaacatta ataataggaa taattataat tacttctggg
    38821 ttattaatcg caactaattt agctccatta tttactcaaa tggctttaaa tgctagtttt
    38881 aaaatgcctg aaggagcaac tatgatttca agtatttgtg atggtgcgaa tccattaagt
    38941 tgggtatttg taaaagttat gaactataaa gttattggag gagtagtttt tggagtcata
    39001 gctttaggaa tggctattta caataggaat agaataataa atgaaaataa aaagctattt
    39061 atagaagaat aaggttaaaa caattttatt aaggagtgta taagttatga aaaaatataa
    39121 atatgattct aaaaggtact tacttagcgt tacaatacca ggatttttta tgattttaat
    39181 attgatttat gcactgttta ataactatat aaattttaat ttgaatatat atagtttttt
    39241 aataattgtt tgtacttatg gtatattcaa tactttcata tcatcaagta atcctaaaaa
    39301 aattattatt gataacaaat gtatacattt ttcttcattt atgactacac ataagtatga
    39361 aattaaagat atagaaaaga taagaataag agaattttat aataaaaaaa tttatctaaa
    39421 aattaatgaa ggaaaccttt ttaaaggtag gtattggata agaacaaata tgtttaataa
    39481 tagtatagaa ttatatagct atttaattga gttggaagag tgcttatatc cagattcatt
    39541 aaagtttaga aataaaagat ttgagaataa gaacatatag aaataaaaaa attaaattga
    39601 agcctagttt aatatgtttt gatagaatat gagtttgagc ttcatgctga atttttagaa
    39661 ttttcaatta aaataataat ataatgtcta agcaattaga gacgtataag gcatgtatat
    39721 aatgaatggg aggatttaat taatgttatt agacaaatta agaaaagaag tattacaagc
    39781 atctttagac cttttaaatt ataatttagt gacattaaca ggaggaaatg taagtggtag
    39841 agatgaacaa actggctata tagcaatcac cccaagtgga atggattata gaaatcttat
    39901 accaagtgat attgttatag tagatgtaga tggaaatgtt atagatggaa aatggaaagc
    39961 atcagtagat ttaccagacc acttgtatat atataaacat agagaagaca taaatagtat
    40021 aattcataca cattctacat actcaagttg ttttgctatt ttaaatgaac ctatagaatg
    40081 tgcaagtaca actcttgcaa atgaagtagg aggttcagta ccagttgcaa aattttcacc
    40141 accaacgtct aataagatgg gaaaatgtgt tattgaagca attggtgaca aaagagcatg
    40201 tcttttagca aatcatggtg taattgcagt tggtccatct gtaggacacg ctcttacagc
    40261 tgctgtaatg ttagaagatt cagcaaaagt atattactta gcaaaatcaa ttggcacacc
    40321 agtgctactg cctgatgaag aaattcaaag agctagagat gtatttttta atgtctatgg
    40381 tcaggataaa taaacgagat aaaattttaa aagtaatatt aaaatataga tattcaatga
    40441 tattaaggag atttataatg atataataag tttaatagtt aagaagtaaa atatgaaatg
    40501 taatcgtata taaattcact taagactaac aaataataag ataaaataaa aaaggagtct
    40561 gtatttctat gtattactta ttaaacaaaa gcacaaatcc ttactttaat ttagcattag
    40621 aagaatatct gtttttaaat gataaatata atgatgatat tataatcata tggaggaatg
    40681 aagaatccat ttttataggt aaaaatcaaa atccatatca ggaagtacat catgatgtta
    40741 ttgaaaaggg cgaaattcct attttaagaa gaatatctgg aggaggcact gtttatcatg
    40801 atttaggtaa tattaatatg tcattcatac aaaaagatag acaacttcat gagatagatt
    40861 ttttggagca tactaagttt atgcaaaaga tgctcttaac cttgggatta ggtgtatcta
    40921 taactgaaag aaaggattta tttttaaatg ggaaaaaaat ttcaggctct gcacagtcta
    40981 taaaaagaaa aaattctctt tatcatggaa ctcttcttta cgattcagat ttaaataaat
    41041 tgactaagta tttaaactca gataaatcaa ctgaatctaa tgcaactaag tctgtttcaa
    41101 gtaaagttac aaatattaag tttttgctcg aaaaaaatat aagttatttt ttagattatt
    41161 gtgttgaata tttaaaatct aatataaaaa atataaaaga acttgaatta gatgaagaag
    41221 atattaaaaa tgtatacaat ttagtagaag ataagtataa aaagatagag tggacatatg
    41281 gtaaaacgcc taaatttcaa gtggtgctac catttaataa taaaagtaaa attaatatac
    41341 atgttaatag atggaaagta tcaaaatttt ttatttctta tgatgataat gtaattaata
    41401 tggacaagtt gttggattta aatttcttta aagaagaaat aaaagagagt attttagaaa
    41461 attatccaca ttacatagat ttaattaatt taatatttta atataaaacc tctaatttga
    41521 taaaattgtc ttatatcaaa ctagaggttt ttaatatttt tacatatcaa taaccattaa
    41581 aaaattgtaa aattaaaaac aatactattg aaaaatcaat atatattgta ataaatatac
    41641 atgtttttca ttagtaaata gacattagct atttatacaa ccgaaaattt aatatataat
    41701 taatcagatg gttaaaataa aaaatattaa aagttttaat aaatgatggt taaaaataaa
    41761 atacgaggtg ataccatgta tagtgttata attgttgcgg caggaagtgg aaggagaatg
    41821 cacttagaca taaacaaaca gttcataaaa ttaagagaaa aagaaattat tgctcataca
    41881 attcaagttt tttatgaaaa tataaatata gatgaaatag tggtatgtat aaagaaagaa
    41941 gaagaagatt tttttaagga aaacataata aataaatata attttaaaaa cataaaaata
    42001 gcatatggtg gaaaagaaag acaggattca atatataatg gtttaaaaga attagataaa
    42061 aattgtgata tagtacttat acatgatgga gcaaggccat ttgtagacca tagaataatc
    42121 aacgaatcaa taaaggtagc taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt
    42181 gatactataa agatagtatc agatggaaca gtacaagaaa ctccagaaag aagtttgctg
    42241 tgggcagcac aaacccctca aacatttgaa tataatctca taatagatgc ttatgaacaa
    42301 gcatataaaa ataattatta tggtactgat gattcaatgt tagtagaaaa tataggtcaa
    42361 agtgtcacta tggtaatggg ttcatatgaa aatataaaaa taactagtcc agaagattta
    42421 aatatagcag aacaaatatt aaatatggaa aaaagagatg aagttaatag tagaaggaga
    42481 attatatgag aataggatta ggatatgatg tacacaaatt aacagaggat agaaagctta
    42541 taatcggcgg tgtagagata ccgcacgata aaggtttgtt ggggcattct gatgctgatg
    42601 tattgataca tgcaataatg gattctattt taggtgctct agcattagga gatataggga
    42661 aacatttccc agatacagat gaagaatata agggagcaga tagtatgaaa ttattagaac
    42721 atgtgtataa tctaataaca agtaaaggat ataaaattgg aaatatagat agtactataa
    42781 ttgctcaaag tcctaagatg gctccataca ttgagaatat gagaagtaat atatcaaaag
    42841 ttttaaacac agacattgat aatataaaca taaaggcaac aacagaagaa ggtcttggtt
    42901 ttacaggagc aaaacaggga atagcttcac aaagtatttg tttattattg ttgacaagtc
    42961 agaataatta atatattatt agtaataagt ttaatggata tcaagtaata ggcctatata
    43021 gaatatctat aatgtgtgaa tttaagtgaa attaatataa atataaaatt agctatgata
    43081 aagaaatagt aaatgatgaa atcttcacag agaggaaacg gtggtgagag ttttcaagag
    43141 gaagtctttg aacctgtctt ttagcttaaa ggtataaaaa tctttacggt aggaaccgtt
    43201 atattcccaa aagagagcta ttcatatagc taactagagt ggtaccgcgg aaattaaacc
    43261 tttcgtctct atacttgtat agagatgaga ggttttttat attttcagaa agttaatatt
    43321 caggaggaat ctattaatga aaatgtcaaa aatgtttatg ccgacattaa aagaagtccc
    43381 agcagatgct gagattacaa gccatcaatt aatggttagg tcaggcatga taaaaaaaat
    43441 gacttcaggt gtttataacc aattaccaat ggggttaaga gtgttcaaaa aaattgaaca
    43501 aataattaga gaagaattaa ataaaaaaga ttgtcaagaa atactttgtg cagccttact
    43561 tccttctgaa ttatggaaag agtctggaag gtggactgct atgggtgaag aaatgtttag
    43621 attaaaagac agaacagaaa gagagtattg tcttgggcca acacatgaag aagcattcac
    43681 tgacataata agacaagaaa ttacttcata taaacaattg ccactgaact tgtaccaaat
    43741 acaagtaaaa tatagagatg agagaagacc aagatttggt gttatgagaa ctaagacttt
    43801 tacgatgaag gatgcttata gttttgatgt agatgataaa ggtctagata agtcatatca
    43861 agatatgttt gatgcatatg taagtatatt tgatagatgt ggattggaga atagccctgt
    43921 acaggcagat tcaggagcta taggaggttc tacatcaact gaatttatgg ttaagtcaga
    43981 agttggtgaa gatgaagttg tattttgtag tggatgtgac tatgcagcca atgtagaaag
    44041 agcagaatct tgtaatgtag catcagaaaa agaagaaatg aaagaattag aagaggttta
    44101 tacaccagga gcagctacaa taaaagagct agaagaattt ttaaaaactt ctccagataa
    44161 gtttgctaaa actttagtat atgaggcaga tggaaaaaca gttgtagtcg ttgtaagagg
    44221 tgatagggaa gttaatgaaa tcaaagtatc taatgctatt ggctctgtta tagaatttgc
    44281 acttgctaca gatgatgtag tgagaaaggt gactaatgca gaagtaggat ttgcaggacc
    44341 aataggtata aatgctgatt atgtatttat agataaagaa attgttgaac aaagaaacat
    44401 agttgttggg gctaataaaa ctgagtacca tataaaaaat gctaactatg gaagagattt
    44461 tgaaggagta gttggagact ttagaaatgt tcaagaaggc gacaaatgta tagtatgtgg
    44521 taagccactt gaaatagcta ggggtgttga agtaggacat atatttaaac taggaactaa
    44581 gtactcagaa tctatgaatg caaacttcat agacagagat ggaaaatcaa agcctatagt
    44641 aatggggtgt tatggaatag gtgttgaaag aacagcagca gctataattg aacaacataa
    44701 tgatgagaaa ggtataatat ggcctttatc agtagctcca taccatgttg tgatagttcc
    44761 agcaaatatg aagaatgaag aacaaatatc aatagctgaa aaaatatata atgatttaca
    44821 ggctatgggt gtagaagttt tattagatga cagagatgaa agaataggtg tcaaattcaa
    44881 tgattcagaa ttaataggaa tacctatgag aattacagta ggtaaaaata ttaatgaagg
    44941 taaagtagaa tttaaattta gacataaaga agataaagag ataattgaca tagaagaaat
    45001 aaatgaaaaa gtaaaggcag agtttatcag aaataatgtt aggttaggat aataacttaa
    45061 ataagatatt gtatagataa tcagagttgt actttataga caccatttta tctatatata
    45121 aggatataaa atggtgtttt tttataaaac aaataaatga ggaggtaatt gaaatggcaa
    45181 aaaatgaaaa acaatttgtt gaagaaataa caaagatgga agatgatttt ccacaatggt
    45241 acacagatgt aataactaag actgacttag ttgattatgc accagtaaaa ggttttatgg
    45301 ttgtaaagcc atatggatat gcattatggg aaaagatgca ggaatttatg gataaaaaat
    45361 ttaaagaaac tggacacaaa aactgttatt ttccattatt aataccagag agtttattaa
    45421 acaaagaagc agaacacgtt gaaggttttg ctccagaagt tgcatgggta acacatggag
    45481 gaaataaaaa attagaagaa agattatgtg taagacctac ttcagagact ataatatgta
    45541 caatgtatgc gaagtggtta aaatcatata gagaattacc atacctttat aatcaatggt
    45601 gctcagttgt tagatgggaa aaatcaacta gacctttctt aagaacatct gagtttttat
    45661 ggcaagaagg tcatacatta catgaaacag cagaagaagc acaagaagaa acaatacaac
    45721 aattagaagt atataaagca ctatgtgaag aattacttgc aatgccagtt gtagctggtc
    45781 aaaaaagtga aagtgagaaa tttgcaggtg gtgaaagaac atatactata gaagctatga
    45841 tgcatgatgg taaagcatta caatcaggta caagtcactt cttaggtcaa cactttacta
    45901 aggcttttga tattactttt gcagatagag aaggaaactt agctaatcca tatcatacat
    45961 cttggggagc atcaacaaga cttataggtg gacttataat gactcatagt gataacagag
    46021 gtttagtatt accaccaaga gtagctccaa ttcaagttgt tatagttcct atagctgcca
    46081 aaaaaggaaa tgtaatggaa actgttgata aaatatatgc tgatttaaaa gctaagggag
    46141 tagctgtaga agttgatgat agagataact atacaactgg atggaaattt aatgagtggg
    46201 aaatgaaggg tgttccagta agaattgaaa ttggaccaaa agatatagaa aacaatcaag
    46261 ctatggtatt tagaagagat actttagaaa aggattctat gcctttagaa ggattagctg
    46321 atgctgtatg tgatttattt gatgttatac acaatgatat gtttgaaaaa gcaagaaaac
    46381 atagagaaga caatacatct atagttgaaa atatggatga gtttagaaaa gctttagaag
    46441 aaaagccagg attcataaag actatgtggt gtggagatgc agaatgtgaa gctaagatta
    46501 aggaagaaac aggagcaact ataagatgct taccttttga acaagaaaac ttaggtcaca
    46561 agtgtgtgta ctgtggaaaa gaagcagata gtatggtagt aatggcaaaa gcttattaaa
    46621 ataatacatt taaataaaaa ctggggtaga aagtatttaa tactttatcc cagttttttt
    46681 attttttatg agaaataaaa tcgtgtttgt agatgtatca taagataagt cataaatgct
    46741 tatattaaaa agaatataat agagaactat ttttaataat tacatattaa tgaaagaaaa
    46801 atatgtttga tatgtaaatt ttcaataaag taaacaataa atataattga atattaataa
    46861 agagtacttt taatttttag aaaataaatg acttaaaaga aagatttatg aaattaaaac
    46921 taggattttc tgatataata aacatgtgta tttttaaata aaaaggatat tattattaga
    46981 tttgattaaa aataaacttg caaaacaatg tactagttta atattatagt tatattgaat
    47041 aaaatatcag gaggaagtaa aaatgaatgt aagagtaagg tttgcaccaa gtccaacggg
    47101 atttgtacat ataggtagtt taagaactgc tttatataac tatttatttg caaaaaaaat
    47161 gggcggagaa tatatattaa gagtggaaga tacagaccaa agtagattag tagaaggtgc
    47221 aatagagaat atgcttaatg ctatgaaatg ggctggtgtc aaccatgatg aaggtgttgt
    47281 attagatgat agtggaaaag tggtacaaaa aggagaatat ggtccatata ttcaatctca
    47341 aagattagat atataccaag aatatataaa gcaacttttg gatagtggaa aggcttatta
    47401 ctgtttctgt acaaaagaaa gactagatga agtaagagat gctcaaagag cagcaggaga
    47461 aacagctaaa tatgatggtc attgtaaaaa tctttccaaa gaagaagtag aagcaaatat
    47521 aaaagcagga ataccatatg ttataagatt aagattgcca gaaaatcata caattaaatt
    47581 tacagattta gttagaggag atatggaatt taacactaat gacttagatg accaagtatt
    47641 aatgaaaaca gatggatttc caacttatca ttttgcagta gttgttgatg actatttgat
    47701 gaaaattaca catgttataa gaggagaaga atgggtatca tctactccaa aacatgttta
    47761 tttatatgaa gcttttggat gggaagcacc tgtatttgtg catttaccaa atatacttaa
    47821 taaagaaaag aaaaaattaa gtaaaagaca aggtgatgta gcagttgaag actttaagaa
    47881 aaaaggatat ttaccagaag gattagtaaa ctatgtagca ttagttggtt ggtctccaga
    47941 agataatcaa gaattgttta caatggaaga attagaaaaa gccttctcta tagaaagagt
    48001 atctaaaagt ggtggagtat ttgatactga aaagctaaat tgggttaatc agcattatat
    48061 aaaagatggt gatgatgctt acctaacaga cttagcaata ccatttttaa tagaagatgg
    48121 atttataaca gaagaagagg ctactaataa atatgatttc ttaaagagta tgatatcagt
    48181 acttaaagag aaattacaat atgtaaaaga ggttactgag catgcaagta tattttttgg
    48241 agataaaata gaggtagaaa ctgaagaggg aagagagttc ttaagattag aacatatacc
    48301 tactttaata gatgctttga aagaaaaaat agaaaaagca gaagtattaa atgctgagtt
    48361 cgttcaagct atgcttaaag aaatacaaaa agagtacaaa ataaaaggaa aaaatttatt
    48421 tatgggctca agaataattt taacagggca aatgcatggt ccagatttac caaaagtaat
    48481 ggaagtttta ggaaaagaaa cttgcttaaa tagaatagct tatgtaaaaa ataatatatt
    48541 atagtcataa aagtccgcta atttagaagc ggactttttt cgtgttagta tttggtgaaa
    48601 atatctgctt aagaaaatga aggtatttaa ggtaataaat ttaatatata aaaagcaaag
    48661 caaaaatata aataaaatat gaataggaaa ctaataaaat attaagcata gaagaaggga
    48721 atctattatt ttagtttgat ttaattatta agggggtaat tattatgtat agtaatattg
    48781 atgatgttaa aaaggaatta aaggagctat gcttagaata tgttacaatt ttagaaaaat
    48841 taaaagatga aaaaatgatt acagaagaaa cttttgaaaa gtgctcttct caaaaaaaga
    48901 tatttttaga agaacaatag aggatagtaa tagtattatt attatgtagt ttgaaagata
    48961 gtacgaaaaa tgatagtaat actattattt attgcaattt tcaactataa tataatatat
    49021 aatgttaaga agataattta taaaaataca gtgaggtgat gagtgtgaaa gtttataata
    49081 cattgactag aacaaaagaa gaatttgttc cattagaaga aggaaaggta aaaatgtatg
    49141 tgtgtggtcc aactgtttat aactatatac acataggtaa tgcaagacca tttataatat
    49201 ttgatactct aagaaggtat ttagagtata gaggatacga tgtaacttat gtacaaaact
    49261 ttacagatgt tgatgataag attataaata gaagtcatga ggaaggaata tctcctgaag
    49321 aagttgctgc taagtatata aaagaatatt ttgtagactg tgatgggcta ggaattaaaa
    49381 gagctactgt tcatcctcag gttacagata atatacaaca aattatagag tttataaaag
    49441 aattggaaga taagggatat gcatatgcag taaatggtga tgtatatttt gatacaaata
    49501 aatttgaagg atatggaaag ctttcaggtc aaaaacaaga agatttagaa gcaggggcta
    49561 gaattgaggt taatgaccaa aaaagacatc ctatggattt tgttctttgg aaagcaaaaa
    49621 aagaaggtga gccaggatgg gatagtcctt ggggagaagg tagaccagga tggcatatag
    49681 aatgttctgt tatgtctaag agatatttag gtgagacaat tgatatacat gcaggtggtc
    49741 aggatttaac attcccacat catgaaaatg aaatagctca aagtgaagct agaagtggaa
    49801 aaacattctc aaaatactgg atgcataatg gatatataaa tataaatgat gaaaagatga
    49861 gtaaatcaaa aggtaatttc tttacagtaa gagatatatc aaaactatat gatttagaga
    49921 tagtaagatt tttcatgtta tcagcacatt atagaaatcc agtaaacttt agtgatgaga
    49981 tgttaaatca agctaaagca ggtcttgaaa ggttatataa tactaaagaa aaattagagt
    50041 ttacgttaag taatttagta gaatctcctt taacagaaaa agaagtagaa cttgttaaag
    50101 aattagatgg atttagacaa aagttcatag atgctatgga tgatgatgtt aatacagcag
    50161 atgcagtaag tgtaatattt gaattagcta agttaataaa ttctaatgta gatgaaaatt
    50221 cttctctgga gtttgctaaa aaatgcttag atgaatttaa tgaacttaca ggagtattaa
    50281 atattgtaaa taagaaaaag gatactgtat tagataaaga cattgaagaa ttgatacaaa
    50341 aaagaactga tgcaaagaaa aacaaagagt ttcaattagc tgatgatatt agacaacaat
    50401 tactagatat gggaattgta ttagaagaca caagacaagg tgttaagtgg aaaaggatat
    50461 aaaaatggaa aaaaccgaat tagttactat gtcaccacta gttttagcat acttaggtga
    50521 tacagtttat gaaacatata taagagaaca tttaattaga cagaatacac aaaaaaaagt
    50581 taatgatttg cataaattag ctataaaata tgtaaaagct aaagctcagg caacaataat
    50641 tcatgaaatt gaaattgaat taactgagga agagagtaaa atttataaaa ggggaagaaa
    50701 tcaaaagtca aatacttctc ctaagaatgc agatattata gactataaac atgcaactgg
    50761 gtttgaagcg ctagtgggat atttgtattt aaataatgaa atagagagac ttcaatatat
    50821 tatcaataaa ggaatcaaaa ttattgaaag agatatgtaa atattaaaga gtgttgtctt
    50881 aataataagt aataaggcaa cacttttttt ataactaatg tataataaat atatagaaat
    50941 tagtaatgag aaaggataaa aaattatgaa agtaaaatta atatcacata cacctgaacc
    51001 agaaaaagta atagctatgg cagctaagct atgttattca ccagttggga cagacgaaat
    51061 agaaaaagac ttaacagatg aaagtataga gaaattttta aatatgttat taagtatagg
    51121 tcatgggtca atattagaac atgcatcatt tacattttca atagaaggta tttcaagagc
    51181 ttgttcacat caaattgtta gacatcgtat agctagtttt tcacaacaaa gtcaaagata
    51241 tgttaaatta gaacaatttg agtacataat tccgccagaa atagaaaaaa tagaaaaggc
    51301 aaaagagtta tttatagact ctatgaaaaa agaccaagag aattatgata agttagttga
    51361 aatattgttt gaaaatcatt ataatgacct gataaaaaac ggtaaaaatg agaaaacagc
    51421 taaaagacaa gctgaaaaga aagcaataga agatgctaga tacgtatttc caaatgcatg
    51481 tgaaacaaaa atggtattta ctataaatgc tagaagtttg tttaatttct ttgaacatag
    51541 atgctgtgaa agagcacagt gggaaataag aaatttagct gtggagatgt taagagaggt
    51601 taaaaaggtt gctcctatat tatttaaaaa gacgggtcca agttgtgtaa atggaagttg
    51661 tccagaagga actatgacct gtggagatat agttcaagtt agagaaaaat ttaaggcctt
    51721 gtaggaggtg aatagtttgg caaatataga aggaagaaat ccagtaatag aagcaataaa
    51781 aagtgacaga gaaatagata aaatattaat tgcaaattca gctaaagaag gttcaattaa
    51841 gaaaataata ggaatggcta aagataagaa tataattatt cagtatgttg ataaacataa
    51901 gttagatgaa gtaagtacaa gtcattcgca tcaaggtgta atagcttatg caagtgagca
    51961 taagtattat gaattagatg agctaataga tttggtaaag aataaagatg aagacccatt
    52021 tttcattata ttagatgaga taacagaccc acataatttg ggttcaataa taaggaccgc
    52081 agatgcagta ggggcgcatg gagttatcat tccaaaaaga aggtctgtac acataactcc
    52141 tgtagttgcc aaagcatctg ctggagcagt agaatatatg ccagtttgta aggtaaccaa
    52201 tatagttaat acaataaaaa ggctcaagga agaagggttg tggattgctg cagctgatat
    52261 ggatggagaa actttttata aacaaaatct tactggtcct cttggtgtag taattggaag
    52321 tgaaggtttt ggaatctcta gattggttaa acaaaactgt gactttatag taaaaatgcc
    52381 aatgataggt aatgttacat ctttaaatgc atctgtagca ggtggaatac ttttatatga
    52441 gatattcaga caaagactgg gtaaaagtaa ataggtatga aaaaaaatat aaatcattac
    52501 ttaataatag atggctacaa tattataaat gcgtgggaca atttgaaaga actggctaaa
    52561 gaggacttag aagattctcg agaaaagctt attgatgata ttatagaatt ttctgagttt
    52621 atgggttata agactataat agtttttgat gcttataatg ttaaaaattc tcgagaaaaa
    52681 gttgagaaaa gaaaacacat aacaatagtt tatacaagag aacaccaaac agcagatagt
    52741 tatatagaaa aatttataac ttctttatca aagtatgatg atgtaaaagt agccactaac
    52801 gactatgcag aacagcaaat gattttagga aaaggtgcta ctagaatgtc tgcaagagaa
    52861 ctaaagttag agttagatcg ttccaagaat aaaatgaagg aaaaaaatat cggtttgagg
    52921 aaaaaaattc agcgaaattg gttggaggaa aggttagata aagaaacatt gtcgaaactt
    52981 gagaacattc gtagaaagcg ttgaaattac taggttcttt agactataat atacctataa
    53041 atttgtttta tatatggggg agatttacat gttggtagca aaagaaaaaa gttatgagtt
    53101 agtggacaat tgtcagcagg atgagtataa cattgtatta agagcaagtg aaggggataa
    53161 aatagcacta gagtacatta ttactaaata cagaaatttt gtaaaggcaa aagcgaagtc
    53221 atatttttta attggcgcag ataaagaaga tataatacaa gaaggaatga taggccttta
    53281 taaggcagtt agagattttg atggaagtaa gaccaattca tttaaatgtt ttgcagaaat
    53341 atgtataaca agacaaataa taactgctat aaaaactgca acaagacaaa aacatatacc
    53401 tttaaattca tatgtttctt tgaataaacc aatatatgat gaagagtcag acagaacact
    53461 tttagatatt atagctacaa gtatagtaac agatccagaa gagcttataa ttagtaaaga
    53521 agagttaaaa aatatagaat caaaaatgaa cgaattgtta agtgacttgg aattagaagt
    53581 actagaatta tatttaaatg gaaagtcata ccagtttata gcggacaagc ttaaaagaga
    53641 tgtaaagtca atagataacg ctttacaaag ggttaagaga aaattagaaa aacatcttga
    53701 aaacagaaat gattaatagt aaaatactta ccataagctt attgtgagca aaattaattt
    53761 atatcgaaag ataagggagg aaattcaaaa tggctaaagc taaatacgaa agaacaaaac
    53821 ctcatgttaa tatagggaca ataggacacg tagaccacgg taaaactaca ttaacagcag
    53881 caataacaaa aacattatat gacagatatc aattaggaga agcagtagat ttcgcaaaca
    53941 tagataaagc tccagaagaa agagaaagag gaatcacaat atcaacagca cacgttgagt
    54001 atgaaacacc aaatagacac tatgcacacg ttgactgccc agggcatgct gactacgtta
    54061 agaacatgat aacaggagca gcacaaatgg acggagcaat attagtttgt tcagcaacag
    54121 atggaccaat gccacaaaca agagagcata tactattatc aagacaagtt ggagtaccat
    54181 atatagtagt attcttaaat aaatgtgaca tggtagatga tgaagagtta ttagagttag
    54241 tagagatgga agtaagagat ttattaacag agtatgattt cccaggagat gacactccaa
    54301 tagtaagagg atcagcgtta atggcattag aagatccaaa gagtgagtgg ggagataaga
    54361 tagtagaatt attcgagcaa atagatgaat atataccagc accagagaga gatacagata
    54421 a
//
LOCUS       DBGJFK010000020        54348 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.020, whole genome shotgun sequence.
ACCESSION   DBGJFK010000020 DBGJFK010000000
VERSION     DBGJFK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54348
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.020"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            3..79
                     /locus_tag="ACOIAP_001426"
     tRNA            3..79
                     /locus_tag="ACOIAP_001426"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Asp,seq:gtc)
     gene            90..164
                     /locus_tag="ACOIAP_001427"
     tRNA            90..164
                     /locus_tag="ACOIAP_001427"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:122..124,aa:Gly,seq:gcc)
     gene            174..247
                     /locus_tag="ACOIAP_001428"
     tRNA            174..247
                     /locus_tag="ACOIAP_001428"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:208..210,aa:Arg,seq:tct)
     gene            1158..1997
                     /gene="cdaA"
                     /locus_tag="ACOIAP_001429"
     CDS             1158..1997
                     /gene="cdaA"
                     /locus_tag="ACOIAP_001429"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGZ2638317.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            1994..3175
                     /locus_tag="ACOIAP_001430"
     CDS             1994..3175
                     /locus_tag="ACOIAP_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGZ2638318.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMNDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVHGTIEDPIQGQKEVY
                     LKANIPQGVTIEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKKNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVNLNDNKDNDALKNYKLSKEQVTIKGKKEDIDKINYIKTKPIDLADLANGE
                     EKEVSLEVPEGITLEGASITIKLNDTKQLSAEFLYSAGDIELRNIPTNMDNPSVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            3479..4381
                     /gene="ptb"
                     /locus_tag="ACOIAP_001431"
     CDS             3479..4381
                     /gene="ptb"
                     /locus_tag="ACOIAP_001431"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050182 - phosphate butyryltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019605 - butyrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HGZ2638319.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            4403..5482
                     /gene="buk"
                     /locus_tag="ACOIAP_001432"
     CDS             4403..5482
                     /gene="buk"
                     /locus_tag="ACOIAP_001432"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HGZ2638320.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            5472..6149
                     /locus_tag="ACOIAP_001433"
     CDS             5472..6149
                     /locus_tag="ACOIAP_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2638321.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6192..6407
                     /locus_tag="ACOIAP_001434"
     CDS             6192..6407
                     /locus_tag="ACOIAP_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2638322.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            6436..7515
                     /locus_tag="ACOIAP_001435"
     CDS             6436..7515
                     /locus_tag="ACOIAP_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HGZ2638323.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGRLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            7515..8267
                     /locus_tag="ACOIAP_001436"
     CDS             7515..8267
                     /locus_tag="ACOIAP_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HGZ2638324.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8268..8825
                     /locus_tag="ACOIAP_001437"
     CDS             8268..8825
                     /locus_tag="ACOIAP_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HGZ2638325.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            8997..10343
                     /gene="glmM"
                     /locus_tag="ACOIAP_001438"
     CDS             8997..10343
                     /gene="glmM"
                     /locus_tag="ACOIAP_001438"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGZ2638326.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCMPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQSAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSELASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            10610..12442
                     /gene="glmS"
                     /locus_tag="ACOIAP_001439"
     CDS             10610..12442
                     /gene="glmS"
                     /locus_tag="ACOIAP_001439"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGZ2638327.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEEEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELVSEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIVLDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKDIPSKIQEIL
                     DNEEYIKEVAKTVVNSDHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            12934..14229
                     /locus_tag="ACOIAP_001440"
     CDS             12934..14229
                     /locus_tag="ACOIAP_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGZ2638328.1"
                     /translation="MANDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDKKDEVLEQALKTKRIDIDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADNENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFENSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGFTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFTSNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFVLVDNRTWDEYIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            14700..15437
                     /locus_tag="ACOIAP_001441"
     CDS             14700..15437
                     /locus_tag="ACOIAP_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HGZ2638329.1"
                     /translation="MKRVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNIKINSVINHNLSNKEFYNIFIEIINNLKLDKKGINWNRKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGRTLIYIATPIIKLDY"
     gene            15458..16711
                     /gene="murA"
                     /locus_tag="ACOIAP_001442"
     CDS             15458..16711
                     /gene="murA"
                     /locus_tag="ACOIAP_001442"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGZ2638330.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            16798..17862
                     /gene="spoIID"
                     /locus_tag="ACOIAP_001443"
     CDS             16798..17862
                     /gene="spoIID"
                     /locus_tag="ACOIAP_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HGZ2638331.1"
                     /translation="MKNPLIVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIKDKSNKEEKNIVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            17928..18596
                     /locus_tag="ACOIAP_001444"
     CDS             17928..18596
                     /locus_tag="ACOIAP_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HGZ2638332.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVNVKKEQKITEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            18694..18954
                     /gene="spoIIID"
                     /locus_tag="ACOIAP_001445"
     CDS             18694..18954
                     /gene="spoIIID"
                     /locus_tag="ACOIAP_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HGZ2638333.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19151..20170
                     /locus_tag="ACOIAP_001446"
     CDS             19151..20170
                     /locus_tag="ACOIAP_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HGZ2638334.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20186..20614
                     /gene="fabZ"
                     /locus_tag="ACOIAP_001447"
     CDS             20186..20614
                     /gene="fabZ"
                     /locus_tag="ACOIAP_001447"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGZ2638335.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(20725..21234)
                     /gene="yyaC"
                     /locus_tag="ACOIAP_001448"
     CDS             complement(20725..21234)
                     /gene="yyaC"
                     /locus_tag="ACOIAP_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HGZ2638336.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      21423..21526
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            21662..22855
                     /gene="metK"
                     /locus_tag="ACOIAP_001449"
     CDS             21662..22855
                     /gene="metK"
                     /locus_tag="ACOIAP_001449"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGZ2638337.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGIVDYLRPDGKTQVTVEYEGNKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEDTKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVASGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23168..24265
                     /locus_tag="ACOIAP_001450"
     CDS             23168..24265
                     /locus_tag="ACOIAP_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638338.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     VGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGIFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCILYRRITKTEGYKENKSEIS"
     gene            24529..26748
                     /locus_tag="ACOIAP_001451"
     CDS             24529..26748
                     /locus_tag="ACOIAP_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGZ2638339.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKVYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIDVINKNPYQLAEDIRGIGFKVADSIANKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELSGKIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEENKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMISSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYVLFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPITWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            26793..27533
                     /locus_tag="ACOIAP_001452"
     CDS             26793..27533
                     /locus_tag="ACOIAP_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGZ2638340.1"
                     /translation="MINKCLDFIYPENISCIICDKSIKKTNTYSICKSCFKEMNFIQD
                     GCMKCGKPIIHHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDVTKKIVLGLKYNQKT
                     FMAKYIAQIMKEKLYLENIKFDYVLFVPLHKKRLNKRGFNQAQKIAFNLSKIVNIPLL
                     DCISRKKYTRMLYKLNKKERKEELKNVFVVKENIKLINNKNILLIDDIFTTGLTTNEI
                     SKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            27865..29778
                     /locus_tag="ACOIAP_001453"
     CDS             27865..29778
                     /locus_tag="ACOIAP_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2638341.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNEIANDFECSERTIRNDCKY
                     IDEWLSTFCNACIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEIGKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMFTIEENMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSSNIKKSLYLNEELANYTRKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            29919..30227
                     /locus_tag="ACOIAP_001454"
     CDS             29919..30227
                     /locus_tag="ACOIAP_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGZ2638342.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30252..30578
                     /locus_tag="ACOIAP_001455"
     CDS             30252..30578
                     /locus_tag="ACOIAP_001455"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2638343.1"
                     /translation="MKRKVYLFCSFGMSTSLLAEKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            30618..31952
                     /gene="celB"
                     /locus_tag="ACOIAP_001456"
     CDS             30618..31952
                     /gene="celB"
                     /locus_tag="ACOIAP_001456"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGZ2638344.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     SNFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSVHEFIFKFL
                     QIPLLKLGNTLSATAIAYVFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGT
                     KLPNIITAQFQDMFATFGGAGSTLSLIIAMLLICKSKRIKSIGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFALVPTVNIIIAYFCMSTGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLIILGIFMYIPFIKMLDKQYLKDEKSNVEGEDDDISFDDLVL"
     gene            31963..32481
                     /locus_tag="ACOIAP_001457"
     CDS             31963..32481
                     /locus_tag="ACOIAP_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdB-related putative oxidoreductase"
                     /protein_id="HGZ2638345.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEPFLNE
                     SKVIATLFCGDEFFINNEEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKADIPAFAAMSEENIDVINEYKNDICIVRTPKKGGIGLNDSLNNICKLAKAMANK
                     EDITLMKEEFCY"
     gene            32577..33536
                     /locus_tag="ACOIAP_001458"
     CDS             32577..33536
                     /locus_tag="ACOIAP_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HGZ2638346.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEEYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            33585..34637
                     /locus_tag="ACOIAP_001459"
     CDS             33585..34637
                     /locus_tag="ACOIAP_001459"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HGZ2638347.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKIRNLNNYIGYAEHGDSEDYVCVIGHVDVVHEGDGWKYQPYKGE
                     EINGRIYGRGVLDNKGPIISALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVLLGFIENVSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKFSFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            34640..35314
                     /locus_tag="ACOIAP_001460"
     CDS             34640..35314
                     /locus_tag="ACOIAP_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGZ2638348.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIERV
                     VNSVKIPVNVMIRPHAKSFVYSKEDINIMQKDVSVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKTLKDYDKIINILTSGGKGSIVDNIQIIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRMNNSPFEDIDRQKLRQL
                     VNIISR"
     gene            35867..36418
                     /gene="raiA"
                     /locus_tag="ACOIAP_001461"
     CDS             35867..36418
                     /gene="raiA"
                     /locus_tag="ACOIAP_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGZ2638349.1"
                     /translation="MNIIISGKQIELTDAIKNKIESKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            36550..39225
                     /gene="secA"
                     /locus_tag="ACOIAP_001462"
     CDS             36550..39225
                     /gene="secA"
                     /locus_tag="ACOIAP_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGZ2638350.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPISKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39240..40347
                     /gene="prfB"
                     /locus_tag="ACOIAP_001463"
     CDS             join(39240..39314,39316..40347)
                     /gene="prfB"
                     /locus_tag="ACOIAP_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGZ2638351.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNKQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEEDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            40492..42633
                     /locus_tag="ACOIAP_001464"
     CDS             40492..42633
                     /locus_tag="ACOIAP_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGZ2638352.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAENYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKENFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVNSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DREVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHIAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIDEIDEKIKEIGLKELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMILKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            42781..43947
                     /locus_tag="ACOIAP_001465"
     CDS             42781..43947
                     /locus_tag="ACOIAP_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HGZ2638353.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIEEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPVDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTYGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIADELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVIYTIINGKVVYEKK"
     regulatory      44007..44124
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44248..44853
                     /locus_tag="ACOIAP_001466"
     CDS             44248..44853
                     /locus_tag="ACOIAP_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGZ2638354.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            45183..46223
                     /locus_tag="ACOIAP_001467"
     CDS             45183..46223
                     /locus_tag="ACOIAP_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HGZ2638355.1"
                     /translation="MNLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENLERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKSQTEELCLEAIKYNYK
                     ALEYVKEQTEYICLEAIKKDCNALKYVRNKTEGLIIKVIRHSTNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVENQTEKMCIEAVKQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVDNKTEEICINAIRYLNKKYNIKDVLCYVDNYT
                     EDMCIEIVRQNGKMLMYIKNQTEKICIEAVKENYKSLKYVKEQSERICKEALKQNYKA
                     KEYVKIAIDDCI"
     gene            46362..46814
                     /gene="tsaE"
                     /locus_tag="ACOIAP_001468"
     CDS             46362..46814
                     /gene="tsaE"
                     /locus_tag="ACOIAP_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGZ2638356.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIKDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            46814..47530
                     /gene="tsaB"
                     /locus_tag="ACOIAP_001469"
     CDS             46814..47530
                     /gene="tsaB"
                     /locus_tag="ACOIAP_001469"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGZ2638357.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTANNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     MNFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVIEFDALVEEIVSTNEEFIM
                     VGEAVYKYKDKLENIENIKIPSPANNVSKAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            47520..47996
                     /gene="rimI"
                     /locus_tag="ACOIAP_001470"
     CDS             47520..47996
                     /gene="rimI"
                     /locus_tag="ACOIAP_001470"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGZ2638358.1"
                     /translation="MEDNINLIVNDIKIEEMTIEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLDGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48002..49018
                     /gene="tsaD"
                     /locus_tag="ACOIAP_001471"
     CDS             48002..49018
                     /gene="tsaD"
                     /locus_tag="ACOIAP_001471"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGZ2638359.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANMDFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAQKGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDSGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            49315..52023
                     /gene="hpdB"
                     /locus_tag="ACOIAP_001472"
     CDS             49315..52023
                     /gene="hpdB"
                     /locus_tag="ACOIAP_001472"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HGZ2638360.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLNEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTHHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKSVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLREDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52027..52284
                     /gene="hpdC"
                     /locus_tag="ACOIAP_001473"
     CDS             52027..52284
                     /gene="hpdC"
                     /locus_tag="ACOIAP_001473"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HGZ2638361.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDEACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            52277..53227
                     /gene="hpdA"
                     /locus_tag="ACOIAP_001474"
     CDS             52277..53227
                     /gene="hpdA"
                     /locus_tag="ACOIAP_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HGZ2638362.1"
                     /translation="MSSQKKLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKAYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSSEVFNKIFEDIDFAFIDIKHMDREKHKEQTGVYNDLILKNIS
                     NLANSDWNGRLVLRVPVISGFNDSVKNISDIISFMHKNNLVEINLLPFHRLGESKWVQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(53335..53571)
                     /locus_tag="ACOIAP_001475"
     CDS             complement(53335..53571)
                     /locus_tag="ACOIAP_001475"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGZ2638363.1"
                     /translation="MTSVYKKTNDNVYLYNLEKTLDEIFQLFDLSLRYSFKTFSNLET
                     MENTSFLEGTSGIILLLISISSKDSTYKKLLFLS"
     gene            complement(53591..54118)
                     /locus_tag="ACOIAP_001476"
     CDS             complement(53591..54118)
                     /locus_tag="ACOIAP_001476"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGZ2638364.1"
                     /translation="MLIIYFMISVIVPTSFLLILQGTQPSYSGIIKFIFTPITSLTTI
                     YIFFSEEYAWRGFLQNIFFDRFGKKLGVIILGMCWSLWHLPLIFTLYTPETPILGLIL
                     RSIHIVGIAIFLGYLYMKTKNVWFCAIIHILNNSAFLITNVEESIITYSDILIVSMVS
                     LIFYVPFLFTKEYKG"
BASE COUNT        21905 a         5798 c        10313 g        16332 t
ORIGIN      
        1 gcggcctggt agttcagttg gttagaatgc cagcctgtca cgctggaggt cgagggttcg
       61 agccccttcc aggtcgccaa attaaataag cgggaatagt tcagtggtag agcgcaacct
      121 tgccaaggtt gaagtcgcga gttcgaatct cgtttcccgc tccataataa tttgggtgca
      181 tagctcagct ggatagagca acgcccttct aaggcgtgtg tccggggttc gaatccctgt
      241 gcgctcatta agaaaagttt actataattt atagtaaact tttatattgt ttaaaaagac
      301 acaggtaata tacatgtatc ctgtgtcttt ttatttataa actttaaact atgtaaaaat
      361 tatagtatat tctaatagag ttacagtata ttcattaatg ttgtaaacat atgaagggta
      421 atgtataata gtctacaagg tgtttatgaa ggcaatagtt aaatatgact aattggatag
      481 aaactatata cattatattg tatactttat ggtatttata aagagattca ttttgcctaa
      541 acaataagta taagaaatta tacaaaaatt agatactata atggattgac aatttaatgt
      601 aatgtttata agttatacta aataaattat tatactgtga agtatatata actttaggta
      661 ttgtgtatta ttttcactgt agaagattct atctagttat acatgatgag ttttaatgat
      721 agtttatagt aagatattaa aatatattta tctaatctag atatgaaatg agttattact
      781 ttaatataaa aatgaaccta atgaaacaat attgatgata agtaatactt aaattttgta
      841 tctgtatata gttgataaat gtattataga atttacaata attaatatat tttagagaat
      901 aaaattgcat taaggcgcga gtactacttt gtattcgcgc cttgatagct tgaattattt
      961 aagtaaaagt aattttaata aaaaataagt atttattaag ttgatatttt taatgtgttt
     1021 agagattatt taacaatctc taaatataaa actagaatta tttacataaa agttaaatag
     1081 tttgtataga gttagattta tatagtataa tacttagtgt aaataattaa gaagttatca
     1141 aacaggagga taaaactgtg ttagatataa attctttttt aaatggattt tttaatataa
     1201 tattaagaat gagtatatat gatttaattg acatatctat agtagcatat attttttaca
     1261 aaatatttat gtttataaaa gatacaagag cagaacaagt gtttaaaggt ataatatttc
     1321 ttttattagc aactcaactt agtaacacct ttaaattgca taccgtttat tggatatctc
     1381 ttaaggcttt agattatgga gttatagctg ctcttataat ttttcagcca gagtttagag
     1441 caggacttga acatatagga agagcaaagt ttaatttatt tggaaagaat gtaaatactt
     1501 ctgaagaaac tctcaataga aatatagaag aaattgtaga agctttatat tcactttcta
     1561 gacaaaaaat aggtgctctt atcataatgg agagagaaac tagaataagt gatataataa
     1621 atacaggaac tattattgat gctgaaattt ctaggcaact gttaataaat atatttatac
     1681 caaatacacc attacacgat ggagctgttg taattagaga ttctaaggta aaagcagctg
     1741 catgtttttt gccattgaca gaaagtaagg atttaagtaa agatttgggg actagacata
     1801 gagcaggaat aggagtaagt gaggtgtctg actgtataac cttgattgta tcagaggaaa
     1861 caggtggcgt atcaattgct aaagcaggta agttatatag agatatttct agagaaagaa
     1921 tgatgaatat attacgtagt aatttaaaaa caaatacaga aacaagaagt tttttcaaag
     1981 gtggtatatt taaatgataa acagattaaa aaataatacc aaaataaaaa taatatcatt
     2041 tttaagtgca attgcattat ggatgtatgt tatggctgta gttgaccctg aagaaactaa
     2101 agggtttgaa gatatacctg tatctataag taatatgaac gatttgaagg ataaaaatct
     2161 tgttatatat ccagacgaaa aattaacagc agatgtatat ataaaaggta gtttatcaaa
     2221 ggtacaaagt gttaagaaag aagatataca tgtacatgga actattgaag acccaataca
     2281 aggacagaag gaagtgtatt taaaagcaaa tattcctcaa ggtgttacta tagaatttaa
     2341 gcatgatgtt ttagtagtga atcttgaaaa aaatataaaa gaaaaaagag atataaaggt
     2401 agaagtaagt ggaaattcaa aaaaaaatat aaataaaatt gaacttagta aggaatttgt
     2461 cgatgtgtcg ggtccaagaa ctctagttaa agaagtcaaa agtgtaagag ctaatttaga
     2521 tgttggtaat gagacagatg atttttctaa aaaattgcaa ttaataccat taaatagtga
     2581 tggaactaaa gttgaaggag taacattaag ctcatctttt gtgactgcaa aaatagaact
     2641 gttaaaggaa aaaattgtcc caataagagt aaatctaaat gataataaag ataatgatgc
     2701 actgaaaaac tataaattaa gtaaggaaca agttacaata aaagggaaaa aagaagatat
     2761 agacaaaata aattatatta agacaaaacc tattgactta gctgatttgg ctaatggtga
     2821 agaaaaagaa gttagcttag aagttccaga gggtataact cttgagggtg cctctataac
     2881 aataaaatta aatgatacaa aacaattgag tgcagagttt ttatatagtg caggagatat
     2941 tgaattaaga aatatcccaa caaatatgga taatccaagt gtaatttctg atgtagatat
     3001 aaaagttgtt gtagagtcaa cagaagattt gagtaagtta aataaaaaag atatttcatt
     3061 atatattgat ttatcacaag gtcctgagga agatagtaaa tataaaataa aatatgaaac
     3121 aacatatcaa tttaaaaaaa taaatataga acctaatatt gttgaagtgg aatgaacaaa
     3181 tatttcgaat atttagttgt tacaagatgc gacaaaaaaa cctataaaat taagtttgtt
     3241 aattttatgt ttttgttgca tcttgtttat tttagttata ttataaaata aggacaatga
     3301 gatatttgtt aaatctaaaa agcgctagat atatgaaaaa agactgataa atagatttaa
     3361 ataaatattt tgaattaaat atttcaatta tctctaggaa aacgttgctg aacgagttat
     3421 aatttaattg agatataaaa agttctattt caaaaaattc aagatgaggt ggaaatgcat
     3481 gagaagtttt gaagaagtaa ttaagtttgc aaaagaaaga ggacctaaaa ctatatcagt
     3541 agcatgttgc caagataaag aagttttaat ggcagttgaa atggctagaa aagaaaaaat
     3601 agcaaatgcc attttagtag gggatataga aaagactaaa gaaattgcaa aaagcataga
     3661 catggatatc gaaaattatg aactgataga tataaaagat ttagcagaag catctctaaa
     3721 atctgttgaa ttagtttcac aaggaaaagc cgacatggta atgaaaggct tagtagacac
     3781 atcaataata ctaaaagcag ttttaaataa agaagtaggc cttagaactg gaaatgtatt
     3841 aagtcatgta gcagtatttg atgtagaggg atatgataga ttatttttcg taactgatgc
     3901 agctatgaac ttagctcctg atacaaatac taaaaagcaa atcatagaaa atgcttgcac
     3961 agtagcacat tcattagata taagtgaacc aaaagttgct gcaatatgcg caaaagaaaa
     4021 agtaaatcca aaaatgaaag atacagttga agctaaagaa ctagaagaaa tgtatgaaag
     4081 aggagaaatc aaaggttgta tggttggtgg accttttgca attgataatg cagtatcttt
     4141 agaagcagct aaacataaag gtataaatca tcctgtagca ggaagagctg atatattatt
     4201 ggctccagat attgaaggtg gtaacatatt atataaagct ttggtattct tctcaaaatc
     4261 aaaaaatgca ggagttatag ttggggctaa agcgccaata atattaactt ctagagcaga
     4321 cagtgaagaa actaaactta actcaatagc tttaggtgtt ttaatggcag caaaggctta
     4381 attttaaggg ggaaataggc aaatgagcaa aatatttaaa atcttaacaa taaatcctgg
     4441 ttcgacatca actaaaatag ctgtatttga taacgaggat ttagtatttg aaaaaacttt
     4501 aagacattct tcagaagaaa taggaaaata tgagaaggtg tctgaccaat ttgaatttcg
     4561 taaacaagta atagaagaag ctctaaaaga aggtggagta aaaacatctg aattagatgc
     4621 tgtagtaggt agaggaggac ttcttaaacc tataaaaggt ggtacttatt cagtaagtgc
     4681 tgctatgatt gaagatttaa aagtaggagt tttaggagaa catgcctcaa atttaggtgg
     4741 aataatagca aaacaaatag gtgaagaagt aaatgttcct tcatacatag tagaccctgt
     4801 tgttgtggat gaactagaag atgttgctag aatttctggt atgcctgaaa taagtagagc
     4861 aagtgtagta cacgctttaa atcaaaaggc aatagcaaga agatatgcta gagaaataaa
     4921 caagaaatat gaagatataa atcttatagt tgcacacatg ggtggaggag tttctgttgg
     4981 agctcataaa aatggtaaaa tagtagatgt tgcaaacgca ttagatggag aaggtccttt
     5041 ctctccagaa agaagtggtg gattaccagt aggtgcatta gtaaaaatgt gttttagtgg
     5101 gaaatatact caagatgaaa ttaaaaagaa aataaaaggt aatggtggat tagttgcata
     5161 cttaaacact aatgatgcta gagaagttga agaaagaatt gaagctggtg atgaaaaagc
     5221 taaattagta tatgaagcta tggcatatca aatctctaaa gaaataggag ctagtgctgc
     5281 agttcttaag ggagatgtaa aagcaatact attaactggt ggaatcgcat attcaaaaat
     5341 gtttacagaa atgattgcag atagagttaa atttatagca gatgtaaaag tttatccagg
     5401 tgaagatgaa atgattgcat tagctcaagg tggacttaga gttttaactg gtgaagaaga
     5461 ggctcaagtt tatgataact aatgataaaa gaataagaat cataactggt cactatggaa
     5521 gtggtaaaag tgaatttgcg atgaactatg ttgttaagtt aagagatatg gtttctggca
     5581 aagttgctat agccgattta gatgtggtaa atgtatactt tagaactagg gaaaagaaag
     5641 agttaatgaa atctttaggt atacaaccaa tagatagctc aattaatgct ccaacattag
     5701 atttaccagc agtatcagca gaggtgatgt ctcctatggt ggaccattca tacaattctg
     5761 ttatagattt aggtggagat aatgtaggtg ctagggttat aggaagattt agtcatttgt
     5821 taaaagaagg cgactatgat atgctttttg taataaatgc aaatagggag aaaactcaaa
     5881 cttctgaaga agttatccaa tatataaaag aaatagaaaa atcttctaaa ttaaaggtaa
     5941 caggtctaat taataatact catcttatta gatttactac tattgatgat gttttaagag
     6001 gtcagaaagt tgcaaaagaa gtttctgaaa aatgtaatat accaataaga tatgttgcat
     6061 gtttagaaaa tcttgttgaa cagttaccaa aagatttaga aggagaaatt tttcctataa
     6121 aattatatat gagagaagac tggatgtagt ttgagctcaa atatatagaa agtttaagga
     6181 ggcttaggta aatggctaaa ggaaaagtat cttttaatca agaacgttgt aaaggttgtg
     6241 gattgtgtgt tgaagcatgt ccagtaaaaa tcatacaatt agactcaaat gtaataaaca
     6301 aaaaagggta taacccagca actgtttttg aaatggaaaa atgcatagga tgtgcaagtt
     6361 gtgcaactat gtgtccagat gtagttataa cagtagaaag agattaattt aattaatatt
     6421 taagggggaa ttttaatggc taagatactt atgaaaggta acgaagcatt tggaaaagca
     6481 gctatagaag ctggttgcaa atatttcttc ggttacccaa taactccaca aagtgaatta
     6541 ccagaatatt tatcaagaga gttacctaaa ataggtggag cgttcgttca agctgaatca
     6601 gaagtttctg cgataaacat ggtttatggt ggagcaggtg caggagcaag agttatgact
     6661 tcttcatctt caccaggagt tgctttaaag caagaaggaa taacatatgc agtaggagca
     6721 gaagttcctt gtgttgtact taatgtaatg agaggtggtc caggacttgg aagtatacaa
     6781 ccttcacaag ctgactactt catgtctaca agaggtggag gaaatggaga ctacagaact
     6841 ccagtattcg caccagctac agttcaagaa gctgttgata tgataatgga agcttttgat
     6901 gttgcagatt attacagatc accagttatg gtagttgcag atggtatgat aggtcaaatg
     6961 atggagccag ttgaatttag agctcctgag aagaaaagag aattgcctcc taaagattgg
     7021 gcaactgttg gaactaaagg aaaaagaaaa cctaatgtaa taaactctct atacttagag
     7081 ccagaagtac tagaagacca ttgttggcat ttacaagaaa aatttgatgc aatggaaaaa
     7141 aatgaagtac aatatgaaat gtacaaaaca gaagatgctg aatttgtatt tgcagcttat
     7201 ggaactactt caagagtagt aaaaagtgca attgatatat taagagaaga aggaataaaa
     7261 gcaggtctta taagacctaa agtattatgg ccattcccat tcgaagcatt caaccaaatt
     7321 cctaatgcta gaaacatatt gactgttgaa atgagtatgg gacaaatggt ggaagatgtt
     7381 aaaatggcag tagaaggtag attaccagtt tacttccatg gaagaccagg aggaatgact
     7441 ccaacaccag cagaaatagt tgaaaaagct aaaaaaatta ttgccggaga attggttgca
     7501 ggaggtgcta gataatggct gttgtattta agaaaactga aggattacaa gatactcaaa
     7561 ctcactactg tccaggatgt acacatggta taatccatag attagttggt gaagtgttag
     7621 aagaactagg agtattaggt gatgctgtag gtgttgttcc agttggatgt tcagttttag
     7681 gatataaata ttttaactgt gacactcaag aagctgctca tggtagagca ccagctgctg
     7741 ctacaggaat aaaaagagtt catcctgaaa atacagtatt cacttatcaa ggtgatggag
     7801 acttagcttc aatcggtact gctgaaatag ttcatgcagc tgctagagga gaaaaaataa
     7861 ctactatatt tgtaaacaat acaacttatg gtatgactgg tggacaaatg gctccaacta
     7921 cattagttgg acaaagagct actactgctc aatcaggaag aaatgctgaa actcaaggat
     7981 atccaataag agtaagtgaa atgttagcta cattaacagg agctgtattt gtagaaagag
     8041 tagcagttga tactccagct catgttagac aagctaaaaa agctataaag aaagcattcc
     8101 aagttcaaca agcaggatta ggatttggaa tagtagaagt attatctact tgtcctacaa
     8161 actggggact agctccaaat gatgctttac aatggttaag agacaatatg ataccatact
     8221 atccattagg aaatttcaaa aatgttgaag ttgaggaggt gaagtaaatg tctacagcta
     8281 gagtaatatg tgcaggcttc ggaggccaag gtgttatgtc tatgggacaa ttacttactt
     8341 atgcagggat gctagaagga aaagaagttt cttggttacc atcttatgga ccagaaatgc
     8401 gtggaggtac agcaaactgt gcagtaactg tatctaatga accagttggt tctccactta
     8461 taacagatga tgcaactgca gctatattat taaatatacc agcatttgaa aaattcaaag
     8521 atgatgttat tcctggtgga aaaataatag taaatagttc tttaataaaa gaaaaagttg
     8581 atagaacaga tgtagatgtt tattatatac cagcaaatga attagcagct gaattaggaa
     8641 atgataaagt tgctaatatg ataatgttag gagcttactt aaaagtatct gatactgtag
     8701 atatagaatc tgtactagaa gcattcaaaa aagttttcgg acctagaaaa gaaaaattcg
     8761 ttccgttaaa cagagaagct ttacaaaaag gtatggatgc tacatgctct aaagcaacta
     8821 actaataaag aagaaaagat gtcaaaaaaa agacaataga attatttcta ttgtcttttt
     8881 tgctgataag tattaaaata tttttatgac tgaaattaag cctataatga tattttatga
     8941 actataaaaa tataatacaa attacaagct tttcaattat gaaaggagaa tctttagtga
     9001 gaaagtattt tggaacagat ggagttagag gagtagcaaa tacagaacta acatgtgatt
     9061 tagcatataa acttggtaga gctggtgggt ttgtcttagc tcaaggagac cacagagtaa
     9121 aagtagtagt aggtaaggat actagaatat caggtgatat gttggaagca tctttaatag
     9181 caggacttat gtctgttgga tgtgatgtta ttactgttgg aataatacca acacctgcag
     9241 tggcatattt aactagaaaa tatggtgctg attgtggtgt ggtaatatct gcatctcaca
     9301 atcctgttga atataatgga atcaaattct ttaataagaa tggatataaa ttagatgatg
     9361 aaattgaatt gaaaatagaa gaatatatag atgatataga caaaattgat tgtatgccaa
     9421 ttggtgaaaa tgtaggaaga aaattacatg agcattgtgc acaaagagat tatgtagact
     9481 atttaaaatc aataataagc actgacttta aggggttaaa agtagtttta gactgtgcta
     9541 atggtgcgtc atataaagta gcaccaatag tgtttgatga attaggagca agtgtaattt
     9601 caataaatag ttcaccagat ggaaataata taaactataa atgtggctct acgcatccag
     9661 aacaacttca aagtgctgtt ttggaacata atgctgactt aggtcttgca tatgatggag
     9721 atgctgatag attaattgca gtaaatgaaa agggtcaaat tgttgatgga gaccatataa
     9781 tgatattgag tgccttaaat ttaaagaaaa ataataaatt agcacaagat actttggtag
     9841 ttacagttat gagtaatata ggattaacaa tagctgctaa ggaaaatgga ataaatttat
     9901 ctactacagc agttggagat agatatgttt tagaagatat ggttaaaaat ggatataatc
     9961 ttggtggaga acaatctgga catatgatat ttttagatta caacactact ggagatggag
    10021 tgcttagttc tctaatactt gcaaatataa tcttgcaaga aaagaaacct ttatcagaac
    10081 ttgcatcaat aatgagtcaa tatccacaag tattagtaaa tgcaacaata aaaaatgaaa
    10141 ataagaacaa atatatggaa tatccagaaa taaaaactga gatagaaaga atagaatcta
    10201 ttttagatgg aaatggtaga gttttgataa gaccatcagg aactgagcca ttagttagag
    10261 ttatgttaga gggtaaagag gaaggtcaaa taaaagaatt agcaacaaat ttagctaatc
    10321 ttatacaaga aaaattatcg taatttaaag ggtattctca gatataaata ctgaggacac
    10381 ctttctaagc gccagaactt agttatagac ataattattg agtaatatag gaactaagtt
    10441 gacgaggtca gagttaatcg aattgtcggc ggatgctctg cggtgtgttt accatcgaaa
    10501 gacttcttta aataatagga gtaatcctat ggacaaaggg aagccaaagt aaacttatat
    10561 gacctaactc ttaaaatata taaataatat ttttaggagg acacaaataa tgtgtggaat
    10621 agttggatat ttaggaagta gaaaggcagc agaagttata gtagaaggac tttctaagct
    10681 agagtacaga ggttatgact cagcaggagt agcagttaat agttctaatg aagaagaact
    10741 taatattaga aagtttaaag gtagactttc tgtacttgca gaagatttag aaaagaaccc
    10801 tattgatggg aatttaggga tagggcatac aagatgggca actcatggag aaccatctga
    10861 tgtaaactca catcctcatt ttaatcaagc caaaacaata gcagttgttc ataatgggat
    10921 aatagaaaac tatatggaaa taaaagaaga attagtttct gaaggtgtta aatttgaatc
    10981 tcaaacagat acagaggtaa tagcacattt agtagataaa tattatgagg gtaatttatt
    11041 agatgctgta tacaaaacta tatcaaaatt aagaggagct tatgcattag gtgttatatg
    11101 taaagaacat ggaaatgaat tagttgcagt aagaaaagat agtcctcttg tagttggtgt
    11161 tggtgaaggt gaaaacttta tagcatcaga catacctgca ttattaaaat atactagaga
    11221 tgtttatttc ttagaaaatg gagaagtagt tcatctaaaa gacgaaaatg taacagttta
    11281 tgactctaat agaaatcttg tggaaaaaga agtatttcat gtaacttggg atgtagaagc
    11341 tgcgtctaaa ggtggatatg actacttcat gtcaaaagaa atccatgagc aaccaacagg
    11401 agttagagaa actttagaaa gaagacttga tgataatgga aatatagtct tagacagtat
    11461 aaatatttct aaagaagatt tagaaaagat aaataaagtt tatatagtgg cttgtggaac
    11521 agcatataat gctggattac ttggtaagta tgctatagaa aaatttgtaa atataccagt
    11581 aataactgat atagcctcag aatttagata tagcgaccca tttgtagatg aaaattcatt
    11641 agtaatatta gttagccaat ctggtgagac agcagatact ctagcagtat taagagattc
    11701 aaaggctaaa ggagcaagaa tactttcaat aactaacgtt gtaggttcat ctatagcaag
    11761 agaatcagat gatgtattct atacttgggc aggacctgaa gtagcagttg catcaactaa
    11821 ggcatatact actcaaataa cttctttata catgatagct ttagactttg ctatcaaaaa
    11881 aggaacaata actagagaat tttatgatag tatgatttct aagatgaaag acataccatc
    11941 aaaaatacaa gaaatactag acaatgaaga atatataaaa gaagttgcta aaacagttgt
    12001 taattctgac cacgcattct atttaggaag aggtatagat tatagcttag caatggaagg
    12061 ttcattgaaa ttaaaagaga tttcatatat acatgcagaa gcttttgcag caggagagct
    12121 aaagcatgga acaatagctt taatagaaaa aggaactcct gtaattgcca tagctactca
    12181 agaaaagtta tttgaaaaaa tggtttctaa tatggaagaa gtaagagcaa gaggagctta
    12241 tgtagtagca atagctcaaa gccataataa ggatgttgag aaagctgctg ataaaataat
    12301 ctatatacca aattcagatg atattttatc accaatatta gcagttgtac caatgcaatt
    12361 acttgcttat catgtctctg tattaagagg atgcgatgta gataagccaa gaaatctagc
    12421 taaatcagta acagttgaat aaaaatagat taaaaattaa atagataata tttattgaaa
    12481 aaaactcatc ctgttatttg tattttatag gatgagtttt ttagataaat attaaatttg
    12541 ttttgttttt gctataataa attttataaa aagattgaat taaatcatct gtaaaatgat
    12601 aaatatatag accatataag gtatagagaa taataaatat atagttcata taaagtatag
    12661 tgagtactta ataaacatat agtcgatatc agatatagtg aatacttaat aaacagatag
    12721 tcaatataag acataaaaaa tactagatta tgagaaagat taaaatacat aaggtattag
    12781 taaccttgtg ataaaataaa gtgagtagtt taaaataaaa atataaggaa ctatttataa
    12841 aagaatataa tgaagctaat agagtataag aaaattactt tattttacta aaatgatttt
    12901 aaataaaaaa tttttaaatt gggagtataa attatggcaa atgattttaa aaaagaaaag
    12961 aaagaagatt attttgttaa tcttaaggca atatctactg aagttttaca agaaaaagtg
    13021 caagataacg cttgggttat agttgatact cgcttaaatg atgcttataa tggctggaag
    13081 ttagatggag taaaaagagg tggacatata aaaggagcag tagatttttc tgctaattgg
    13141 ttaagtgtat actcagataa aaaagatgaa gtgctagaac aagcattgaa aactaaaaga
    13201 attgatatag ataaaaatat agtattatat gatgcaaatg gaaaagatgc tttggttgta
    13261 gcagattatt tatctaaaaa aggatataaa tatctatata aatatgatat taaacaatgg
    13321 gcagacaacg aaaatcttcc aatggaaaga tataaaaatt atcaaatgat agttcctgct
    13381 tttataataa aagatatatt ggatggaaaa attcctgaga catttgaaaa ttccaagaat
    13441 ataaaaatga ttgaagcgag ttggggagaa gaatcgtata caaaagggca tatacctaca
    13501 agtgttcatg taaataccga tattatagaa cctcctccaa catggatgct tgataatgat
    13561 gataacttga ctaagtttgc tttagactat ggattcacaa aggatgatac tgtaatagtt
    13621 tcaagtagta cacctatggc atcttataga ctagctgtta tattgagata tataggagta
    13681 aaagatgtaa gagttttgaa tggcggaaca aactcatggt tatcagcagg atatgaatta
    13741 gaatttacta gtaatccaaa acattcatgt actaattttg gagcagatat accagttaac
    13801 tcacaattag ttgttactac atctgaatta agacaaaaac taaaagaaaa aaataagttt
    13861 gtactagtag ataaccgtac ttgggatgaa tatataggaa aagtatctgg atatacatat
    13921 tatgataaaa aagggcgtat accaggagct ttatatggac attcaggtag tgatagtgtt
    13981 tcactagaag aatatcgtaa tattgataat acaatgagaa ataaatatga gattctagaa
    14041 atgtgggaca aggaaaatat agatgtgaat aaacagctta tatttatgtg tggaagtgga
    14101 tggcgtgctg ctgaagtatt aacatacgca aatgtcatag gagtggaaaa tacctcactt
    14161 tatagtgatg gatggatggg ctggagtctt gataattcaa atttaattga agtgggagaa
    14221 cacaaataaa gtttttgaaa gtacgataga gttatttaaa acaaaggtgt ttttgattta
    14281 ttaggaagag tatgtaaatt gtgttttggg aagtgtactt aggtatgttt atttggagct
    14341 atggaaattg ataaaaaagt attatctgtt tattttgctg gtaaaatgtg aatagattat
    14401 agattataga ttatagatta tagattatag attatagatt atagatttag gtatagacta
    14461 agtaatttat attacagaag agaatatata agaactagtg caagatgtat ttgatacata
    14521 taaaaaattg gcaaatccag aagaaggata gagaaaattg agattgaaga gtttgaaaga
    14581 gccttattag atgaaaaata caaagatgta taaaaataca tattgagaaa gtatatctct
    14641 cttaaatttg ttaataattc tattatacag aaaaacatgt ttaaggggga ttttttacta
    14701 tgaaaagagt aaaattagct ataagctttt ttatattaat gattatagga atgacaatat
    14761 cttatgcaga tactagtata aatactagat acaatagatt aagcaaagct cttgaaattt
    14821 cagaagcaaa ttttaaattt tataatatta aaattaattc tgttataaat cataatttat
    14881 caaataaaga attttataat atttttatag aaataattaa caatctaaag ttggataaaa
    14941 aaggaataaa ttggaatcga aaagggtctg gcgataaaat acaattatgt gctactataa
    15001 aaggtagcga taaagaaatt tctataaaag gaataaataa aaataacaaa gaaagttaca
    15061 tagtagttga catattggat aacaaagtat ataaacataa agaggttatt tatagtaacg
    15121 tagaaaatgt gttaaataaa tattcatctc aagtagatgt gtctgcttgt attgttggag
    15181 aatacacaaa aaggttacaa aacaacaaat atgatgatat tttacaaaaa atattatata
    15241 atatgagtgc taagcaaata gatgaagtga aagacgtaaa ctttttatct ataacagcat
    15301 atagtaaagt attaaatgat tatgaattag aatatttagg ggaaaaaatt aatttaaata
    15361 taggaattaa atataatgag gacgacggaa gaacactcat atatattgcc acaccaatta
    15421 taaaattaga ttattaatta tgaggagatc aaaaaatatg gctaagataa tagtaaaaaa
    15481 gagtaatcca cttaaaggta gtgttaaaat agatggtgca aaaaatgcag ttttaccaat
    15541 aatagcagcg actttattag caaacgggaa atcaacatta aatggagtac caaatttaag
    15601 agatgttcat gttatatcag atttattaag acatgtaggg gcagaagttg aatataaaga
    15661 aaatacactt actgttgatg caagcaatat aaaaacttgt gaagctccat atgagcttgt
    15721 aagaaagatg agagcttctt ttttggttat ggggccatta cttgctagat ttaatagtac
    15781 gaaaatttct atgccaggag gatgtgctat aggaacaaga cctatagatt tacatttaaa
    15841 aggatttaaa gctttaggtg caaaaataga gatggaccat ggttttgttg aagcagcaac
    15901 agaaaaatta gtaggaaata aattatattt agattttcca tctgttggag caactgaaaa
    15961 tataatgatg gcagcttctt tggcagaagg aactacaata atagaaaatg cagcagaaga
    16021 gccagaaata gtagatttag caaacttctt gaatgaaatg ggagcagatg ttaaaggagc
    16081 aggtactaat actataaaaa taaaaggtgt taaagagcta aaaggagcag aacataatgt
    16141 aattccagac agaatagaag cagcgactta tatggttgca gcagccatga caaaaggtga
    16201 tataactgtt gaaaatgttt taatggagca tttaaaacca gttgtagcta agttgagaga
    16261 agctggttgt gaaataacag aaatggacaa ttctgtaaga gttgtaggtc caaaggtatt
    16321 aaaaccaata gatataaaaa ctttaccaca tccaggattt cctacagatg ttcaagcaca
    16381 atttatggct atgcttactg tagctaatgg aactggtgta gttatagaaa ctgtttttga
    16441 aaatagattt atgcatgttg ctgaatttaa tagaatgggt gctaatataa aaatagatgg
    16501 aagaagtgcg gttgttaatg gtgtagatga gctacatggt gcagcagtaa acgctactga
    16561 tttaagagca ggggcagccc ttattttatg tggtcttata gcagaaggag aaactcaaat
    16621 aggagaaata taccatatcc aaagaggcta tgttgatata gataagaaga taacggcatt
    16681 aggtggtcaa atcgaaatag tagaagatta ataattggtt tatagaagaa agttataaat
    16741 taatagggtt gttcatatac ttaaatacaa ggttttaaaa gctaaggagg agagtatatg
    16801 aagaacccat tgattgtttt gctaggattt gtaacttgct ctgtgttagt tccatcactt
    16861 ataactttag tttcttataa aaatgtagaa ttaactgaaa aaccagagag cccagtatct
    16921 ataaacaaaa ctattaaaaa aagtgatatt aaagacaaaa gtaataaaga agaaaagaac
    16981 atagtgaact atgaaactgt aaataaaaaa gcaccaatca tcaatgtata taatcatata
    17041 acaggaaaaa ccgaaaaaat ggacatggag aattatttat gtggagtatt agctggtgag
    17101 atgtcttcag agtttgatat agaggcttta aaagctcaat ctgtagcagc tagaacatat
    17161 gtagtatata aacaggaaca tggtaaatca agtaaacata aaaatgcagt agtatgtact
    17221 gattataaac attgtcaaga atataagagt tatgatactc ttaaaaaatt aaatggtgaa
    17281 gaatggatta agaataaata ttccaaaatc caagaagcag ttagaggaac taaaggtcaa
    17341 ataataactt ataatgataa agcaatactt cctctttatt tttctacatc ttcaggaaaa
    17401 acagaaaata gtgaagaagt attttctgca aaatatcctt atttaaaatc tgtggaaagt
    17461 ccttatgata agtattcccc taaatttgca tcaacactta aaataagtaa cacagatttt
    17521 gttaagagtc ttagaagggc atatagcact attgttatag atgtgaataa tttaagtaaa
    17581 caagtctcaa taactaaaag aagtgatgct ggaactgtgg aaaaaataaa attaggaaat
    17641 aaagaattga ctggaaaaga cattagaact gtttttaagt taaactctgc aaactttgac
    17701 ataaaatttg gagaaggata catagacttt gtagtaaaag gatatggtca tggtgttggt
    17761 atgagccagt ggggagcaga aggaatggca gaagagggct ataaatatta tgatatatta
    17821 tcacattact acacagatac aaaaataaaa gatatatact aataattgta taaaatgcca
    17881 aaaacacgtc aataatccaa atgtagaaat atatttggag gtgcaaaatg aagaaaaagc
    17941 tgttagaaaa agatggtttt tatttatctt tgtttgtatg tgtttgttta ttagcagtag
    18001 gtggagtttg gtttacaaat aataatgtag ataaattggc ttctaataaa ggaataatgg
    18061 aaaatgctaa taaagatagt gaagaggaaa tacatttaat tgaaaaagac aagaaagatg
    18121 ctatccctac tgcaactgat tcaaaacaaa acttagaaaa agctaaatca aaagaggaaa
    18181 ataaatcgag tacaacaaaa ttaaattaca ttggagataa agtaataaga ggatattcag
    18241 aaaaagaacc tagttattct aaaacacttg atgtttggga aactcataaa ggtgtagata
    18301 ttagttgtac taaaggcaaa gaagtaaaat ctctattaaa cggaatagta gtagatgtat
    18361 ttaatgatga agaatatgga caatcagtca agataaaaag tgataataac attgtagtag
    18421 tatattcaaa tctagataaa aatgttaatg ttaagaaaga acagaagata acagaaggac
    18481 aatctctagg cactgtaggt agtacttctc aaatagaaag tgaagaaggt atacatgtgc
    18541 atttagaggc atatagtgga gaaaaatcta tagacccaat gagtctaatt aagtaaaagt
    18601 ataacaagtt taatcatatt tggttaagct tgttatattt tttggtgttt ttacatatat
    18661 atcattaaag ctattatgtg aggggggtaa tctttgagat ctcatataga ggaaagggcc
    18721 atagtggtag caaaatatat acttgaaaaa aacactacag taagacaaac cgccaagaca
    18781 tttggagtaa gtaaaagtac aattcataag gatgttacag aaagattgaa ggaaataaat
    18841 ccatcccttg ccaaagaagt taaaaatgtg ctagacaaaa ataaatcaga gagacatatt
    18901 agagggggat tagcaacgaa attaaaatat gagaaagaac ataaaaaaat gtaggttaaa
    18961 aacctacttt ttttatttaa ttaaattata aaaagaaata tattaagtaa ttataaatag
    19021 caaaataata atactctcaa aagatttatt ttctcttgat taaagcgaca tttttgtata
    19081 tgctttatta taggagtatt aaaataggct tataatataa tctaatatta taaataaagg
    19141 agttgaaaga atggctggag ctgatatagg catagattta ggtactgcaa atgtgcttgt
    19201 ttatgttagt ggtaagggaa tcgttttaga agaaccatct gttgtggcga tagacaaaag
    19261 aacagattct gttttagctg tgggagaaga agctaaaaag atgataggaa gaacaccagg
    19321 taatatagtc gctataagac ctttaagaga tggtgtaatt tcagattatg atgtaactga
    19381 gaagatgtta aaatctttta tagataagat agttgataaa aagggatttg gaagattttt
    19441 tatgccaaga attatggtat gcgtaccaac aggtgtcaca gaagtggaaa aaagagcagt
    19501 agaagatgct acgagacaag ctggagctag agaagtatat ataatagaag aaccaatagc
    19561 agcagccata ggagctggtg tagacatatc acagcctaat ggtaatatga ttatagatat
    19621 tggtggaggt actgtagata tagctgtaat atctctagga ggagctgttg taagtgaatc
    19681 tataaaggtt ggtggagata gatttgatga tgctatagtt aaatatatga aaaaacaaca
    19741 caatcttctt ataggagaaa gaacagcaga gaaaatcaag tttgaaatag gttctgcatt
    19801 taagagagaa gaagaaaaat atatgaagat aacaggaaga aatttaatta caggacttcc
    19861 tagttctata actataaatt caacagaaat gttggaagca cttagagaat gtgttgagca
    19921 aatagtagtt gctactcatg ctgttttgga aaaaacgcct cctgagttag cagcagatat
    19981 aggggatgtt ggtataataa tgactggagg aggttcatta ttatatggat tagataaaat
    20041 aatagaacag agaacaggaa taactgttac aatagcagat gaaccattat cttgtgttgc
    20101 aaaaggtaca ggaatagctt taggttcaat agacctactt gaaactggtg ggtctttcaa
    20161 aagaaaataa ttaggagagt ttagaatgtt aaatatagat gaaataaaaa aattaatacc
    20221 acatagatat ccgtttttat tagtagacaa gattacagag ctagaagtgg ggaaaagggc
    20281 tgttggtata aagaatgtaa cagttaatga accatttttc caaggtcact ttccagaata
    20341 tcctttaatg ccaggagtac taatagtaga agctctagca caagtgtgtg gagtggcaat
    20401 gatgtctgta gaggaaaaca aaggaaaatt aggtgtattt gcaggtatag ataaagttag
    20461 aattaagaga gaagtaagac caggagatac attaactatg gaagttgaaa tgacaactct
    20521 tagaaaaaac atagccaagg cagatgctaa ggcatatgta ggtgaagaac ttgtctgtaa
    20581 aggtgaatta atgtttgctt tagtagaaaa ataagaactt aaaatataaa agtaaaaagg
    20641 tagataattt ggagtattta ataagatact ctaaaatatc taccttttta tataaagaat
    20701 tttatcattt agtttatatt gggattaggt ggatactaat aaagccaagg ctattgtttc
    20761 agctaaatcc aatataaagc taagacgtat attattaaat gaaagtttat tattttcatc
    20821 aattttatct acaattccta ctatagaata atttcctatt tgaggtagtt ttttgccaac
    20881 accttttccg ggcaggatag gtccttctct aatctgtata ttacctatgt tactctgcga
    20941 ccccaagcaa gcatctatag ccaagaagtt accttgtata tgtgtatttt ttatagtatc
    21001 tagagactca tatatattta aggcgtgaat agggttatct agtgtaccgt aaacggggta
    21061 tttaaagtta ctgttcttaa gtattgttcc aactaaaggg cctaaagtat cacctatagc
    21121 cctgtctgtt cctatgcaaa caacaatcgt attttcatta attatagttt ttagaactga
    21181 acttagcatc tgtataacat catcatcgct gtaatttact ttagctaaat acaataggaa
    21241 cacccccttc aaaaaaatat atgaataaaa agcattaaaa agacctaact ttaaatttca
    21301 gatagataga aacttttatt tgtcttacaa aaaaaggaat agaaaaaata tgactaaaaa
    21361 tattgacaaa attttaaaaa aatagtaagc tagtaaagta aaacaaaact taaatcttga
    21421 ttaccttatc aagagaggct gagggatagg ccctgtgaag cccagcaacc acccaaatgg
    21481 gaaaaggtgc taattcctac aagacaagag tcttgaaaga tgaggtcagt taattagtat
    21541 gtaattacga ttattaacct cttcttataa aggagaggtt ttttattttg agtaaatttc
    21601 taaaattaaa aataaggtaa aacctataat aaaaactaag aataaacaag ggggaataaa
    21661 aatggcaaga catttattta cgtcagaatc agttacagaa ggacatcctg ataagatatg
    21721 tgaccaaata tcagattcaa tattagatgc attattagaa aaagacccgc aatctagggt
    21781 agcttgtgaa actacagtta ctactggttt agttttagta gcaggagaaa taagtacatc
    21841 tgcttatgta gacattccta aattagtaag agaaacagta agagaaattg gatatacaag
    21901 agcaaaatat ggatttgatt gtgatacttg tgcagttata acttctattg atgaacaatc
    21961 tggagatata gctatgggag ttgatgaagg tctagagagt aagactggag aagagataga
    22021 agaggaaata gaaaaagttg gagctggaga ccaaggtata atgtttggat ttgcatgtaa
    22081 tgagactcca gaattaatgc cacttccgat atctttggca cataaattat caagaagact
    22141 tacagaagtt agaaagacag gtatagttga ttatttaaga ccagatggaa aaactcaagt
    22201 tactgttgaa tatgaaggaa ataaagctgt aagagtacat acagttctta tatcagctca
    22261 acattgtgaa acagtatcaa atgataaaat aagagaagat ttaattaatc atgttattaa
    22321 agaggttata ccagcagaat tacttgatga agatactaaa atttatataa atccaacagg
    22381 aagattcgtt ataggaggac cacaaggaga tacaggtctt acaggaagaa aaataataat
    22441 agatacttat ggtggatatt ctagacatgg tggaggagct ttttcaggaa aagaccctac
    22501 aaaagttgat agatctgctg cttatgccgc tagatatgtt gcaaaaaata ttgttgcatc
    22561 tgggcttgca gataaatgtg agatagaact tgcatatgct ataggtatag ctagaccatt
    22621 atctatattt atagatactt ttgggacagg taaagtttca gaagaaaaac ttgttgaatt
    22681 agtaaataaa cactttgatt taagaccggg agcgataata agagacttag atttaagaaa
    22741 gcctctttat aaaaaagttg ctgcttatgg tcactttggt agaactgata tagatttgcc
    22801 ttgggaaaga actgacaaag tagagcagtt aagaaaagat gctttaggtg aataattttt
    22861 aactaaaaag ctgttagaat gtaattttac aattactttc taacagcttt ttattatgag
    22921 ttaaatattt ttaataaatg ctaatttatc atcatataat acataaacag tatttaatct
    22981 ggtcaataca ttttttataa taatctacta aatttataaa tattatgaga tatatgttaa
    23041 aggatggtta agaatgtgtt aactaatgtt aaataattaa aaatatattg aaatatcata
    23101 ataatgagtc taatataatc ttaataaact tacactttaa aataatttta attgggggga
    23161 gtagtgtatg tcaggtaaag taaatattaa aacggttata agttttgctg gagcttatgt
    23221 tgctactgta ataggttctg gatttgcaac tggtcaagaa atactacagt tttttacgtt
    23281 ttatggatat gctggtattg taggtggaat aatatctatg gtactatttt catggtttgg
    23341 agcagaagtt atagataagg gaagagaatt aaaacttaag gagccaataa aaatttatca
    23401 agtgtattgt ggaaaatacc ttggaatatt ttttgaatgg tttggtccat tgtttttatt
    23461 tggaacatta gtaataatga ttgcaggagc aggagctaca ttatcagagt actatggatt
    23521 aaatccatat gtaggtagga ttggtatggc aatcgtttcc ctaataactg tttcattagg
    23581 tttaacaaga ctttctaaaa tactaggtaa tataggccct ataataataa tatttacact
    23641 tttggtagga gcaattagtt tatttagcaa tattgatgct ttatcaaatg ctggaaatat
    23701 ggttgatagc ttaaatatta aaactgctac atcaaatgga tacttttcag gagtacttta
    23761 tacttgttat aatgtaataa tagtaataac attcttgaca ggaatgggag cttctgcagt
    23821 aaataagaaa gatgctgttt ggggtggtat agtaggtgga gtagcactta tggcagctgc
    23881 tataatgatg aatttggcac tactttcaga cataggaaac atatacacaa aagagatacc
    23941 agcactttac ttagctgata agatatctcc aataataggt attttattct cagtagtact
    24001 tttactagga atatacacta cagctgtacc attgttatgg tcagtaacta acagatttgt
    24061 agaagatgac caccctaaat ttaaaattat aacaatagta gtaagtatat tagcttgtat
    24121 aggaggtcta ctaccatttg ataagttagt aggtacacta tatccatata caggttacat
    24181 gggaatttta attttactat gtattcttta tagaagaatt actaaaaccg agggatacaa
    24241 ggagaataaa tctgaaataa gttagcactg taatattctt atgaaattta atttatactc
    24301 taaacataga gtaattaaaa taaaatagat atttaaatat ggtacctgta tttcatggta
    24361 ccatatttta tggatgcaga ttttttttgt ttctgataaa atgtataata gttggaaatt
    24421 acgttaagta taaaaatata aaacttttct aagattatca tagttttaat atataaaatt
    24481 atactaacat ttaaatggag cgattattag tatttttagg agataaaaat ggaaaaatta
    24541 gaaggaatga taagtgaaat agtctttaaa aacgaagata atggctatac aatagctcat
    24601 ctggtaaatg aaaatgatga gattgtcgtt gtaggatgta tgcctacttt ggcaattgga
    24661 gaaagcatag aagttgaagg aaagtgggta aaccataagg tttatgggac tcagtttgaa
    24721 gtgaatagtt ttatgccagt aacaccatca tccttagaag gaatttatgt ttacttatct
    24781 tctggaatga tacatggtat tggtgaaaaa atggctaaga gaataattga taagtttggt
    24841 gtagatacgt tagaggtgat acaaaattca ccagaaaaac tacaagaagt agaaggtata
    24901 gggagtaaaa aagtaaaaca aatagtaaaa agttatgaag aagacagaga attgagaaat
    24961 ataataatac agctatctcc ttttggaata acaccaaatt actgcctaaa aatatataaa
    25021 aaatataaaa gcagtgcaat agatgttata aataaaaacc cataccaact tgctgaagat
    25081 ataagaggaa ttggatttaa agtagctgat agtatagcaa ataaaattgg tatagataaa
    25141 aactctaagg atagaatttg tcagggtatc ctatacactt taaataaatc tttaagtaat
    25201 gggcatacat atttaccaga gcatgttcta atacaagatt cggaaaaatt attggagcta
    25261 agtgggaaaa taataaaaga gtgtgtaatg atgctagttt ataatcaaaa aatacatata
    25321 gagaaagtaa acaatgaaaa tctcatatat cttatgccat actatctagc tgaaaatgga
    25381 gtatgtagtc aaatagtaaa attatcacag tatgaatttg aagacttaaa aatagatata
    25441 gataacgaga ttaatgtttt agaagaaaat aagaaaatta agttagcaga aaaacaaatt
    25501 ttagcagtca aagaatctgt taatagtgga gtattaatta taactggtgg gccaggaact
    25561 ggtaaaacaa ctactatcaa tgctattata gacatatttg aaaacaatgg taaaagcgtg
    25621 actttggcag ctccaacggg aagagcagca aagagaatga gtgaaacttc taataaagaa
    25681 gcaaaaacta tacatagatt gctagaaatg ggattctcaa cagatgatga tttaactttt
    25741 tttaaggatg aagaagaccc aataaattca gatgtaataa ttgttgatga ggtatcaatg
    25801 gtagacatta ttttaatgta caacttgctt agagctataa agttaggaac aagagtaatt
    25861 ttagttggag atagtgacca attaccctct gtaggtgctg gaaatgtact taaggacatg
    25921 attagttcta atattataaa tgtagttaaa ttaaacgaaa tatttagaca agcgcaagaa
    25981 agtatgataa ttgtaaatgc ccataagata aataatggag aaccacttta tctaaataca
    26041 aaaggtaaag atttcttttt tataagaaaa tcaactaatg aagaaatttt aaatgaaata
    26101 ataggattgg ttaatgaaag attacctaaa ttttataaag ttgataaatt aaaagatata
    26161 caagttttat cttcaatgag aaaaggtgaa ttaggagtta ctaatctcaa tatagagtta
    26221 cagaagtatc ttaacaaaaa agaaaaattt aaagttgaag aaagtttttc taaaagatta
    26281 tttagagttg gcgataaggt aatgcaagta aaaaataatt atacaaaaaa atgggaaaca
    26341 gaagaccaaa aagaaagtgg agaaggtatc tataatggag atataggata tgtttatcac
    26401 atagataaag ataagaaaac tatttatgta ttatttgacc agactaaaat tgtatcatat
    26461 ctatatgatg aattagatga aattgaccat agtttttgta caacgataca taaaagtcag
    26521 ggaagtgaat ttccagttgt agtattgcca ataacttggg ctcctcctat gctacttagc
    26581 cgtaatttat tatatacagc agtaacaaga gcaaagaaat tagttgtatt agttggagat
    26641 gtgaagtatc ttgaatatat gataaaaaat aatagagtta atcaaaggta ttcaaattta
    26701 gggtataagc taaataaatt taagcaagaa gggttgttga tagaataaat atgaaaatat
    26761 gcaatgataa ttttattaag gattttaaaa atatgattaa taaatgtctg gattttatat
    26821 atcctgagaa tataagttgc ataatttgtg ataaatccat aaagaaaaca aatacttatt
    26881 caatatgtaa aagttgtttt aaagaaatga attttataca agatggttgc atgaagtgtg
    26941 gaaaaccaat aatacatcat tcaattgaaa aagagtttat tgaagagtgc agttattgtt
    27001 ttaacaaaga cttttacttt gataaatcaa tatcttgtat tgaatataat gatgtaacaa
    27061 aaaagatagt gttagggctg aagtataacc aaaaaacctt tatggctaag tatatagctc
    27121 aaataatgaa agaaaaatta tatttagaaa acataaaatt tgattatgta ctatttgttc
    27181 cacttcataa aaaaaggtta aataaaagag gttttaatca ggcgcaaaaa atagcattta
    27241 atttaagtaa aatagtaaat attccattat tggattgtat aagtagaaaa aaatatacaa
    27301 gaatgctata taaattaaat aaaaaagaac gaaaagaaga gttaaaaaat gtatttgttg
    27361 ttaaagaaaa tattaaatta ataaacaata aaaatatact tttaatagat gatatattta
    27421 ctactggtct aacaacaaat gaaatctcta aacttttaaa gttatccggt gctaataagg
    27481 tttttgtatt aactctactt acaaaagcaa atgataatta tattatggaa taatcttata
    27541 tattgacaat tttaatttaa aatattaaaa tgaataggtg atatttaggt ctgtggttga
    27601 aagtccaagc cagtcgcagg caaaaggatc cacgtaagtt aacactaaaa attgggttaa
    27661 tgatcatggt gcggcttaga agtaagacct accgataata aaatcgagag agagtagtag
    27721 tgcggcgaac ccaagcgaac cctccagtag gcgagtgtgg ggtcaaaaac caggtcagct
    27781 aaatatcata ttaaaagaga gctagcatac ctttatgtat agctcttttt tatatataat
    27841 aaattaaggt tgagtcataa agaggtgata tgtttgaata aaagacaaga aaatttatta
    27901 acaacattgc tattaaaaga agagtttata aatgttaatg aaattgccaa tgattttgag
    27961 tgttcagaaa ggacgataag aaatgattgc aaatatattg atgaatggct atctactttt
    28021 tgtaatgctt gtatcaaaag aaaacctaat attggaatta aatttagtgg agatggaaca
    28081 gataaaatac tggtaaatca gaagttgcga ggtgaagtta aaagagtaaa tagtgagctt
    28141 cataagcaag ttgagatatt aaatttacta ctttgtaata ataaaaaagt tactttaaat
    28201 gatttgtcta ataagttgta cataaataaa aatattgtca gagaagaaat aggtaaatta
    28261 tcagtggcat taaataatta taacctaaat atctcaacta aaaaaggtag tggtatatat
    28321 attgaagggg atgagaaaga cataagaata atgttagtat cattcttatt taaatacata
    28381 gataaataca gattaaacat agatgaaata gaatatttcc atatagtaga tataataatt
    28441 gtaaaaaaca taatgtttac tatagaagag aatatggata taagacttac agatatatca
    28501 ttcaagcaat tgatgctatt tttgcttata aatataatac gaataaggct aggaaattct
    28561 ttaaaagtat caaatactaa gaaagagctt aagctaaaaa tgcttatact agatatagaa
    28621 gatgaactaa aatctaattt atctatagta ttaaattatg aagaaaagct gtttatagaa
    28681 tctttaatat tgggtatgaa taaacaaata aatagcagta atattaagaa atctttatat
    28741 ctgaatgaag aattagcaaa ttatacaaga aaaattataa atttagtatc agaagaatca
    28801 ggaataaatt tcaataatga tatattactt tatgaacaat taatatgtca tctgaatgtt
    28861 acaatgcatc aaatgaaaag caatgtttac ttagaaaatc cacttttaga taacataaaa
    28921 actaaatttt gttttttatt tacagtaata tcaagttcaa tagaaattga attaaaagga
    28981 aaacaaataa cggaagatga aatcggttat cttacacttc actttcaaac ctctctagaa
    29041 agaaaataca gtaaaaggga atcaaataaa aaagcaagta ttgtatgtcc atttagtttt
    29101 ggagtaagta tgctattaaa agtaaagata gaaaagagat ttgacaacat aaaaattatt
    29161 gaaacattaa gagaggaaga tttaaaaaga gataacttca ataagacaat agattttata
    29221 attgcatttc aagagtatga gaatattcaa aaaccaattt ttataacaac accattattt
    29281 actgatgagg atgagaataa acttaaagag ttcacaaaca aaataaaaga aaaagatact
    29341 tcatataagc ttatgaacag attgatgatg tctgattatt taataagaga gttagaacat
    29401 gatgatattt atgaagctat aacatattta actaatttat tgattgaaaa acattatgca
    29461 gaaaaagagt atttacaatc tattataaca agagaaaagt catacccaac caatgttggg
    29521 aaaggaatat tattccctca tggagatatg aaatatataa aacaatctgt tttatgtttt
    29581 gcaaggttaa aaacaccaat aaaaattaga aatggaaaag atataaagat tatactttta
    29641 ctagcctata aaaaagatga tgatagaaaa gtatttagag aattatttaa agaaatatct
    29701 aatttaactg aggatgaaaa tatgctagat attctaagta aatgtgacat tgaaaaagta
    29761 aaagatattc ttatataaaa ttcatagaga cctatggata agcacaaaat tttccatctg
    29821 atggaaaaag ttgtgcatgt tttttgtttt ttataagata ttatatgttt ataaggtata
    29881 aataatctaa aaacagagaa gcaatttagg aggaaaaaat ggaagaaata gtcttaaaga
    29941 ttataattca cgctggaaat gcaaaatcta tgctttatga agcgcttgat tatgcgaagg
    30001 aaaacgattt taaaaaagcg gatgaattaa ttgaaaatgc aaatgaagaa atcttaaaag
    30061 cacataaagt acaaactgaa cttatacaaa aggaagctgg gggagataaa tcagatatat
    30121 ctattttatt aattcactct caagaccatt taatgacttg tatgagtgag agaaatctta
    30181 taaaagaaat gattatgtta agaaaagaaa ttcaaaaatt aaaatgaaaa atttaagggg
    30241 gatttaaaag aatgaaaaga aaagtatatt tattttgtag ctttggtatg tcaacaagtt
    30301 tacttgcaga gaaaatgcag aaggtggcag atgaacacaa tttaccaata gaagtagagg
    30361 catttccaat agcagaaatt gataaaatag ttgaagaaaa aaatccagat tgtatattat
    30421 taggaccaca agttaaatac atgctaaagg aattaaaacc aaagtttgag gctcaaggta
    30481 aacttataga tataataaat gaagttgatt atggaactat gaatggggaa aaagtactaa
    30541 agcttgctat aaagttaata aaatctaagc aagcatagga ttataaataa aaaacaatga
    30601 gagatgaggg tggatagatg aatagattgg aaagaatact tatgccattg gctgaaaaaa
    30661 taggtaaaaa taagttatta attgcaatta gagatggttt tttaatatca tcaccattat
    30721 taataatagg ttcattattt ttattagtat caaacttccc aataaaagga tggaatgaat
    30781 ttgtaggtca aatttttggt ccagattggg ctgtaaagtt acaacaacca actgtagcaa
    30841 catttgaagt aatgactcta cttgcagttt taggaattgg atattcttat gcaaagcaaa
    30901 tagatgtaga cccaatagca tcagcagcag ttgcaatagt tgcctttttt ataataacac
    30961 catttgtaat accatataca ccagagggaa cagaatcagt atacatggtg acaggtatac
    31021 cactaggttg gatgggttct aagggaatgt ttgtaggtat gataacagca ataacctctg
    31081 taaaattatt tgctgcagtt gtaaaaaaag gatggacatt gaaaatgcca gatggagtcc
    31141 ctccaactgt atcaaaatca tttgcagcat taataccaag tgcaatagtt atggtagttt
    31201 tctttttagt taagatagct tttgaagcta caccatatgg aagtgtacat gaatttatat
    31261 ttaagttttt acaaatacca ttattaaaat taggaaatac tttaagtgct acagcaattg
    31321 cttatgtatt cttacatcta ttctggttct ttggaataaa tggaagtagt gttgttggag
    31381 ctgtgtataa tccaatatta aaaattctat cagctgaaaa cttagctgct tttcaagctg
    31441 gtacaaaact accaaacata ataactgctc aatttcaaga tatgtttgca acatttggtg
    31501 gagcaggtag tacattatca ttaattatag ccatgttatt aatatgtaaa agtaaacgta
    31561 taaaatcaat aggaaaatta tcaattttac caggtatatt tggtataaat gaaccattaa
    31621 tatttggtct accaataatg cttaatccaa tactattgat accatttgca ctagttccaa
    31681 cagtaaatat aataatagct tatttctgta tgtcaacagg attagtgcca cttacaaatg
    31741 gagttcagct accatggaca actccaatta tattctctgg atttctaaca acgggatggc
    31801 aaggggcagt tttacaatta gtacttatta tactaggaat atttatgtat ataccattca
    31861 taaaaatgct agataaacaa tatttgaaag acgaaaaatc aaatgttgaa ggggaagatg
    31921 atgatatatc ttttgatgat ttagtattat aggaggaaga ttatgaagaa aatagtaatg
    31981 atattggatc aaatacaagc tggagcggga ggaaaagaga aaagtaatat acctcctgct
    32041 ggaaaatcaa gcccattagg accaggtgta atgatggaac catttttaaa tgaatctaaa
    32101 gtaatagcta cattattttg cggggatgaa ttttttataa ataatgaaga agaagtgact
    32161 agtaagatga tagctatggt aaaaaaatta aaccctgatg tagtaatctg tgggccaagc
    32221 tttaattatg aaaacttttc taagatgtca gcaatactgt ctaaaaatat aaacgataag
    32281 gcagatatac cagcttttgc agctatgtca gaggaaaata tagatgtgat aaatgaatat
    32341 aaaaatgaca tatgtatagt tagaactcca aaaaaaggtg gaattggtct taatgattcg
    32401 ttaaataaca tatgtaaatt agctaaagca atggcaaata aagaagatat aactttgatg
    32461 aaagaagaat tttgttatta atatgagtat taattattag caagtttgaa tattacacta
    32521 tttataataa gcatatatta ttaaaatcta tatagtttaa ggaggggaat tttagcatgt
    32581 ggggaatgat tgcgacatgg agaatggccc tagaaggaat aactgaggca tcagaacatt
    32641 tagaaaaagg catggaagca ggtgatgctg tagagcttgc tgtaagaaga gttgaagact
    32701 atccattcta taaatcagtt ggatatggtg gacttccaaa tgaaaattgt gaggtagaac
    32761 ttgatgctgc atttatggat ggtaacacat tagatattgg agcagttgct ggtataagag
    32821 attattctaa tcctgtcagt atagctagga agttaagtta tgagaaggta aataattttt
    32881 tagttggaat aggtgctgaa gagtacgctc ataaaaatgg atttgaaaga aaaaatatgt
    32941 tgactgatag agcaaagtta cattataaga aaagaaaaaa agagacttta gataagggat
    33001 taagtccata tgctggtcat gatactgttg gtatgatatc tttagataaa actggaaaaa
    33061 tgtgtgcagc tacatcaaca agtggattgt ttatgaagaa aagaggtaga ataggagatt
    33121 ctgcactgtc tggttcggga ttctatgttg atagtagtat aggaggagct acagcgactg
    33181 gtttgggaga agatttaatg aagggatgta tatcttatga gatagttaga cttatgaaag
    33241 aaggaaaaca tccacaagaa gcatgtgata ttgcagtaaa cgaacttgat aaacagctta
    33301 ttaaaagaag aggaaaagct ggtgatttgt cattagttgc aatgaataat aaaggtgaat
    33361 ggggagtagc tacaaatata gctgatttta ctttttcagt agtaactaaa gaagaatccc
    33421 ctactgtata tatttcaaat agagtagatg gaaagactat acataaggtt atatcaaatg
    33481 agtggatgga agcatatgag gctagaataa aagcaccaat agaagtaagt gagtaaagta
    33541 gtagttacat aattaaaata gagttttata ataaggagat ttttatgaat atcataagta
    33601 ataaaataga tgaattaaaa gaagatttat taagtgatat tatagatatt gtaaaaatac
    33661 ctagtgtcaa aggggagtca gaaaatggct tcccttttgg tgaaaaagta ggggaggcac
    33721 ttaataaagc attagaaata tcagaaaaat tgggatttaa gattagaaat ttgaataatt
    33781 atattggtta tgcagagcat ggagatagcg aggattatgt ttgtgtaatt ggacatgtag
    33841 atgttgtaca tgaaggagac ggttggaaat atcagcctta taagggagaa gaaatcaatg
    33901 gaagaattta tggaagagga gtactagata ataaaggtcc tataatatct gctttatatg
    33961 gattatatgc tattaaagaa ttaaatttaa aattagataa aagagttaga ataatatttg
    34021 gtacaaatga agaaagtgga tttgaagata taccatatta tttagaaaaa gaaaaagcac
    34081 ctatcatggg gtttacacca gattgtaagt atcctgttgt atatggtgaa aaaggcatgg
    34141 caaagattag aataaaaagt aaaataaatt atgaagaaga tgtattatta ggttttatag
    34201 aaaatgtgtc tgaaaatgtg cttgttacat ataaagagct aaatatagaa aatagtgata
    34261 ctatattgga tataaaggta aaatacgatt ttagttataa attaaaagat gtattagatg
    34321 aaataaaatt tagttttcca aatagtatcg atatagaggt aatttctaat tttaatcctg
    34381 tatattttga taaagagagc aatcttgtta aaaagcttca gctggcttat gaaagggtta
    34441 catcactaga tggaactcca gtaacaacta atggaggtac atatgcaaaa gtaatgccaa
    34501 atatagttcc gtttggccct tcattcccag gacaaaaagg aatagctcat aatcctgatg
    34561 aatatatgga tatagaagat ataatattaa atgcaaagat atttgcaaat gcaatatatg
    34621 aattagcaaa ggagtagtta tgttagagat aataggaatg tcagtagaag acgctaaaat
    34681 tatagaagat tgtggtgcag atagaataga gttagttagt gctttaactg aaggtggatt
    34741 gacaccaagt tttggtctta tagaaagggt tgttaacagt gtaaagatac ctgtgaacgt
    34801 aatgataagg cctcatgcga aaagttttgt atacagtaaa gaagatataa atataatgca
    34861 aaaagatgta agtgttgtta aagagattgg tgctaatgga gttgtatttg gtgtattgga
    34921 taaaaacaac aatatagatg agaaaaatct aaatgtttta ttgaaatgtt gtgataatct
    34981 tgatgttaca tttcatagag ctatagatga atcaaataca atagatagtg ttaaaacttt
    35041 gaaggattat gataaaatta taaatatatt aacatctggg ggaaaaggaa gtatagttga
    35101 taacatacaa ataataaaga atatgatgct tagttctaat cacataaaaa ttcttttagg
    35161 tggaggactt aattttaata atatagaaaa gataaaggaa ttaactaagg caagtaattt
    35221 tcattttggt acagctatta gaatgaataa cagtcctttt gaagatatag atagacaaaa
    35281 gcttagacag cttgtaaata taatttcaag atagtatata aatataaaat acttagttta
    35341 aataaagaga gtaagttaat tataatttgg gtatatgaat gttaataggt attacatatg
    35401 aaattattgt tgagtatgct ttacaacttt taagtagttt taaatataaa taatgaaagc
    35461 aaagatatag taacgaggtt ttagagggtt tatatttatt aaaaaattat aaaggtatac
    35521 tggcatataa cacatataat ttcctaaaat taccatctta tgacataaat tcacatatta
    35581 ataaacaatt aatggagatt tttgtggata gaaataggag caaaaatagc tttaaataaa
    35641 caaaaacagg agttattaac agttttatcc acattatcca caggtgtttg taataatatt
    35701 aatccacata agtataaatt taactaaaaa tgataaataa ttctatcaat tgaatagaaa
    35761 aaatcataaa agtaaataat aaaaagagga ttatgagagt tcgcgtagaa tatattatta
    35821 aagtataaat tttcttatac tggcataatt gaagggagat gtacttatga acataattat
    35881 atctggaaaa caaatcgaat taactgatgc aataaaaaat aaaatcgaaa gtaaactaag
    35941 taagttagat aattacattc atccagacac tgatgtaaaa gttacagtaa gtgcgagaaa
    36001 agcaagacaa aaaatagaag taacaatagc tactgtaaat ggacctataa ttagagcaga
    36061 agatatgcag gaaaatttat acacagctat agatgttgta tatgataaat taagtaaaca
    36121 attgaaaaaa tataaaaaga gactacaaga taagcataaa gacaacaaga gtataagatt
    36181 ccaagacgca gagataaatc tagctgatga acaagaggat tatggggatg aaaatcaaga
    36241 attagtaatt caaagacgta agaaatttag tgttaagcca atgagtgaag aagaagctgt
    36301 attacagatg gaactaatag gacatgattt ttatatgttc aagaacatag attcagatga
    36361 aatagcagta gtttataagc gtaataatgg tggatatggt ataatagaac atgaataaag
    36421 caatttagat ttaatcatat tagctatcga taaataaatt atcgatagct ttttaaatta
    36481 atattaaaag tatagttttt atggtaaaat gaataatagt acaataaaga acgaggagag
    36541 atgtaaaata tgagctttat ggataattta ttcaacatgg cagataaaaa agaattaaaa
    36601 aagttcaata agactgttga tataatagat tcattagaac ctaaatttga atctatggca
    36661 gactcggaac ttaaaaatat gacaaatata tttaaagaaa gattagcaaa tggtgaaagt
    36721 atagatgata tacttccaga agcttttgca gtagttagag aagtttctaa gagagtgtta
    36781 ggacttagac actacagagt tcaaatgatt ggaggtatag tactacatca aggaagaata
    36841 gcagaaatga aaacaggtga aggtaaaact ttggttgcta ctgctcctgt ttatttgaat
    36901 gcgcttactg gaaaaggtgt acatgttgta acagtaaatg attaccttgc aaaacgtgat
    36961 agagaccaaa tggcaaaaat ctatgagttt ttaggaatga gtgtaggcgt tattatacat
    37021 ggtcaaaacc caaaagtcag aaaagaacaa tatgattgtg atataactta tggtacaaat
    37081 aatgagtatg gatttgacta tttaaaggac aatatggtaa tacacaaaga gcaaagagtt
    37141 caaagaggat taaattatgc tatagtggat gaggttgact ctatactaat agatgaggct
    37201 agaacaccac ttatcatatc tggacctgga gacaaatcaa ctcacttata ttcggatgca
    37261 aacacatttg ttttaacatt aaaaccagat gattatgaat tagaagaaaa agataaggct
    37321 gtatctctaa cagcatcggg tatacaaaaa gcagaagtat attttaatgt tgataatata
    37381 acagatatat ctcatacaga attataccat catataaatc aagctttaag agcacatgta
    37441 ataatgaaga aagatgttga ttatgttgct aaagatggag aaatagtaat agtagatgag
    37501 ttcacaggta gacttatgtt tggtagaaga tattcagaag gtttacatca agcaatagaa
    37561 gctaaagaag gtcttaaaat acaaagagag tctaaaacac tagctactgt aacattccaa
    37621 aattacttta gaatgtacaa aaaactttct ggtatgactg gtacagcaaa aacagaagaa
    37681 gaagagttta aagcaatcta caaaatggat gttttccaag tacctactaa taagcttatg
    37741 ataagggaag acttgccaga ttgtgtatac aaaagtgaaa taggtaaatt caatgctgta
    37801 gcccaagaaa taattgaaag gcataaggtc aatcaaccaa tacttgtagg tacagtatca
    37861 atagaaaaat cagaattatt gtcacaaata ttaaagaaaa agggcataaa acatgaagta
    37921 ttaaatgcta agcatcatga taaagaggca gaaataatag cacaggctgg tagacttgga
    37981 gctgttacaa tagctactaa tatggctggt cgtggtacag atatagttct aggtggaaat
    38041 ccagactttt taactaagag agaaatgaga agaaatggat ttaaagaaga aatagtaaat
    38101 agagtagata ctccaataga aggtatacct gtaaaaggta atgaaatttt atttgaagct
    38161 agagaagagt atgaaaaact atttgaaaag tttaagcaac aaacgcaaga agaacaaaaa
    38221 caagttgtag aagcaggtgg acttgctata attggtacag aaagacacga atctcgaaga
    38281 atagataacc agttgagagg tcgtgctgga cgtcaaggtg acccaggtag ttcaagattc
    38341 tatataggtc ttgatgatga ccttatgaga ttatttggta gtgatagaat atctggtatt
    38401 gtagataaga taggtcttga agaagacatg cctatagaac atagaatatt atctaagtct
    38461 attgaaggag ctcaaaagaa agtcgaaggt aaaaactttg gaataagaaa gcatgtactt
    38521 caatatgatg atgttatgaa taaacaaaga gaaataatat acgcagagag aaaacgtgta
    38581 ttagaaggcg aagatttaca agaacaaata caatcaatga ctcattctat aatagaagaa
    38641 gcagttactc tttatacaca agataaagga tttgatgaag aaggattcaa agaacatatg
    38701 tataatctgt tcttgccaaa aggtagcata gaaataccag aaatagaaaa acttaatcca
    38761 gttgaaataa cagaaaaagt ttatgaaata gctatgaaga tatatacttc aaaagaagaa
    38821 caagttggct atgagagaat gagagaagtt gagagagtaa tcttacttca agctgttgat
    38881 aaccattgga tagaccatat agatgctatg gaccaattac gccaaggtat cggtcttcgt
    38941 gctgtaggtc agcaagaccc agttattgct tataaaatgg aaggttttga tatgtttgat
    39001 gaaatgaata aacatatcaa agaagatact gtaagatatt tatttaatat aacaatagaa
    39061 actccagtgg aaagaaaagc agttgtagat gttgaaaatc tatcttctcc atcagatgga
    39121 acacttccaa taagtaaaac tgttaaaaaa gatgaaaaag ttggaagaaa tgacttatgt
    39181 ccttgtggaa gtggtaaaaa atataaaaac tgttgtggaa gataatcttg gaggattaaa
    39241 tgttaaagtt acaagaatat agacatagta tggagcagat ggcttcaaat ttagaagaat
    39301 tgagggtttc tctttgacat agcttcattg atgaaaaata tacaaattaa tgaagaaaag
    39361 atgaataaac aagacttttg gaatgataat gaagtcgctc aaagagtact tcaagaaaat
    39421 aagtccttaa aagagacatt agaagaatat gaaagcttaa aaagcttatt agaagatata
    39481 gaagtattaa ttgaaatagg tctagaagaa gaggatgatt ctgtagaaag agatatagaa
    39541 aagtccatag aatcaatgga agaaaaatta tccgaaatga aaataaagac tcttctaaat
    39601 ggagagtatg ataaaaataa tgctatatta tctataaatg cgggtactgg tggattagat
    39661 gctcaagatt gggctcaaat gcttttgaga atgtatataa gatggtcaga aagtaagggt
    39721 tataaagtta agctcttaga tataatatca gaccctgaag cagggataaa gacagctaca
    39781 attcttgtag aagggacaaa tgcttatggg tatttaaaga gtgaaaaagg agttcatagg
    39841 ttagtaagaa tatctccatt tgacccatca ggaaaaagac atacttcatt tgcatctata
    39901 gatgtaacac cagagttaga tgaaaatata gaagtagaga ttaatccatc agatttaaag
    39961 atagacacgt atagagcttc tggagctgga ggacaacatg taaatacgac tgattcagca
    40021 gttagaataa cacatattcc tacaggtgta gtagttcagt gccaaaatga aaggtctcag
    40081 catctaaata aggatagagc tatgagactt ttaatggcaa agttgataga attaaaagag
    40141 ttagaacaaa aggaaaaaat agaagatata caaggcaaat actcacaaat aacttggggt
    40201 agtcaaatta ggtcatatgt ttttcaacca tataaattgg ttaaagacca tagaacaaat
    40261 gctgagtttg gaaatgtaga tagtgtaatg aatgggaata tagacttgtt tattaatgaa
    40321 tacttaaaaa tgaataaaat agtttaataa atatgcattg taattaagat atatgtataa
    40381 gaaggttagt gcttaatatg cacttacagc acttaggctg aggacgataa ccctcagcct
    40441 tcgttctgtt ttgttatact tatgaaaaaa ctaacattag gagtgaataa attggatata
    40501 aatcaaatct taaaaaaaga gtttaatctt agagatgaac aaataaataa tacattaaaa
    40561 cttattgatg aagggaatac aataccattt atagctagat acagaaaaga aatgactggt
    40621 gaaatgagtg atgttacact aagagaattt tatgaaaaat tgatgtattt gagaaatctt
    40681 caaagtagaa aagatgatgt agttaggcta atagatgaac aaggtaaatt aacagatgaa
    40741 ataacacaaa atatagaaaa agcaaaaaca ttgcaagaag tagaagatat atatgctcca
    40801 tataaacaaa agaaaagaac tagagcaaca atagcaaaag aaaaaggatt agaaaactta
    40861 gcattgtcaa tactagagaa taatttagat aatattgaaa tagaggcaga gaattatctt
    40921 gatgaagaga aagaagttct ttctattgaa gatgctctaa aaggtgctag agatataatt
    40981 gcagaattag tatcagatga tgctaagatt agaaagtata taagagaatt agcattaaga
    41041 gaaggtatga tagttagtaa aagtgccact gatgagaaat cggtttatga tatgtattat
    41101 gattatagtg aagcagtaaa aagtatggct ccacatagag ttttggcaat aaacagaggt
    41161 gaaaaagaaa atttcttaaa ggttaagtta gaaataaata atgataaggt tttaaattac
    41221 ataataaatg aatatgtaaa tgataaaaat ttcaaaaata aagaagaaat tgtaaattca
    41281 atagaagatt cctataaaag attaattttt ccatcaatag aaagggaaat aagaaatcat
    41341 ttaacagaaa tagctcaaga aagagctata agtgtgtttg gaaagaatgt taaaagttta
    41401 ttacttcaac caccagttaa agacaaagta gttatgggat ttgaccctgc atttagaact
    41461 ggatgtaaaa tagctgtagt agataaaaat ggtaaactac tagactatac aacagtatat
    41521 ccaacagacc ctcaaaatga tgtagaagga gcaaaaaaag ttttaaaagg attgattgaa
    41581 aaatacgata tagatataat ttcaattgga aatggtactg catctagaga atcagaaact
    41641 tttgtatcag aaatgataaa agagatagat agagaagtgc agtatgtgat agttagtgaa
    41701 gccggagcat ctgtttattc agcatctgaa cttgcaaatg aagaacatcc agatataaat
    41761 gtatcaataa gaggagctat atctatagct agaagattac aagacccatt ggcagagctt
    41821 gtaaaaatag accctaaaag tattggtgtg ggtcaatatc agcatgattt aaataaaaag
    41881 agattagaag aagtactaga tggagttgtt gaagattctg taaacagtgt tggagtagat
    41941 ttaaatacag catcatactc tctactagag catattgcag gaataagtaa agctattgca
    42001 aaaaatataa tagcatatag agaagaaaat ggagatttta catcaagagc acaattgaaa
    42061 aaagtaaaaa gactaggacc tcaagcattt actcaatgtg ctggatttat gagaatctta
    42121 gagggtaaaa atccattaga taatacaggt gtgcatcctg aaagttatga tatatgtaaa
    42181 aaaatgattg agataatcgg gtattcttta gatgatgtaa agaataaaaa tatagatgaa
    42241 atagatgaaa aaataaaaga aattggcttg aaagaattaa gtgaaaaact agaagtaggt
    42301 caagttacat taaaagatat catagctgaa atcaagaagc caggaagaga ccctagagaa
    42361 gaaggtataa aacctatact tagaactgat gtcttaaaaa ttgaagatat acaagagggt
    42421 atgattttaa aaggtacaat aagaaatgtt gtagattttg gtgcatttgt agatattgga
    42481 ataaaaaatg acggattagt tcataaatca gaaatgagta atagttttgt aaaagaccct
    42541 atgagtattg ttacagtagg tgatatagta gatgtaaaag tcattggaat tgacttaaac
    42601 aaaaaaagag ttgccttatc aatgaaaaaa tagataagtt tatgtatggt tatagtactt
    42661 aaattctatg tttgtaaatg aagttaccag agtgtataaa tgttaaaaac ttgtaaaggt
    42721 atatagtaag aaaatacatt aaaataagaa cgatagtctt gaaaatcagg aggaaaatga
    42781 atgattttta taaaaaatgg taaaataaat accataacaa atgggataat tcatggagat
    42841 atacttatag aggaaggaaa aataatagaa atcggagaag atttgatagc acctttagat
    42901 gtagaggtca tagatgcaag taataaactc gtgtttcctg gatttataga tgctcataca
    42961 catttaggtt tatgggaaga tggtataggg tttgaaggag cagacggaaa tgaagagact
    43021 gacccaataa caccacaatt aaatcctgta gatggaatta atccaatgga taggactttt
    43081 aaagaagcat ttgaaggtgg aataacttct gtttgtacaa ctcctggaag tgcaaatgtt
    43141 atgggtggtc aatgtatagc cataaaaaca tatggaaaaa gaattgataa aatggtaata
    43201 aaaaatccag ttgcgtctaa aattgctttt ggggaaaatc caaagagctg ttacggtcag
    43261 gatgataaat ctccccaaac tagaatggca atagctgcct tacttagaga aaacctaaaa
    43321 aaagcagaag aatatttgga agatattgat atgtatgaga gtcatgatga tgaagactgt
    43381 gaaaaacctg aatatgatat aaaaatggaa agtttaatac ctgttttaag aagagaaatt
    43441 ccttttaagg cacatgctca tagagcagat gatatgttca cagcaataag aattgcaaaa
    43501 gaatttaatt taaagcttac attagaccat tgtacagaag gtcatcttat tgcagatgaa
    43561 ttagtggaag aagggtttcc tgtaatagta ggtccatctt tgtcagaaag gtctaaattt
    43621 gagcttagaa atttgacatt taatacagca ggaatacttt caaatgcagg tcttgatgta
    43681 tgtataatga cagaccatcc agtaatacca gttcaatatc ttccaatatg tgcaggtatt
    43741 gcagtcaaac atggtatgaa agaagaaaaa gcaatagaat caattacgat aaatccagct
    43801 aagactttag gaatagaaga tagagtaggc tctatagaag ttggtaaaga tgcagaccta
    43861 gtaatttggg ataattctcc actagagatt caaagtaatg taatttacac tataataaat
    43921 ggcaaagtag tatatgagaa aaaataactt gacaattatt aaaaaattaa ctagtataag
    43981 agtgtaagga aaattaaaaa atcaaagaag atcttcgggg cagggcgaaa ttccctaccg
    44041 gcggtatagc ccgcgaacta cttaagtggt tgatttggtg agattccaaa gccgacagta
    44101 aagtctggat gagagaagat atttatggaa gataaataag tttattttag tttgtttaaa
    44161 ctatatccat aaaaactcga agatagggtc ttcgagtttt ttgtttttcc taaaaaatat
    44221 aaacatattg attaggggga aataattatg caaaacacag ccaaaagagg caatatgatt
    44281 tcaacaagaa ctttagtagt aatgtcaatt ttatctgcaa tatcttattt attaatgttt
    44341 attcaagcac caataccagg tatatttcca gatttcttaa aaattgactt atcagatatt
    44401 ccagcaatat ttggaggaat gtctctagga ccattagttg gatttggaat agttgtagta
    44461 aaaaatgtgt tacaagcaat aacagcaaca acaactggag gaataggaga atttgcaaat
    44521 atattaattg gtggttctta tgtaatgata ctttgttatt catataagag aagtggagat
    44581 ttaaaaggtg tattgattgg ttttgtatta ggaacaatat ctatgactat aattggttca
    44641 ttagtaaatt attttgtaat gttgccactt tatggtcaac ttatgggact agatgctata
    44701 ataggtttag gttcagctat aaatcctcaa gttcatgatt tattcacttt tgtaatttgg
    44761 atgatagctc catttaatgt gctgaaggct gttataatat ctttagtaac attgccactt
    44821 tataaaaaaa tgggaaatat aataaaaaaa taatttagac aagaaaatat aaaattaaat
    44881 gtattgaata gccatagttt atttataact tcagtcctat attgtgattg atatattaaa
    44941 tatattatgg ctttattaat ttatcaaaaa atgtatataa aataagaaat atttagacaa
    45001 atttaaattt taaaataaag gaagaattaa aacgattaac tattaaaata tgaaaaaggt
    45061 atctgcaata tacagagcga atttataata agcaaaaaat aaagttatta ttaaaaaaat
    45121 ataaagatta gtaatcaaat ttttaataat aactaattta ataatgatgg gagtgtatat
    45181 tcatgaactt atctaaaaag ataaaaaaat tatttttaga tgataaaggg tattatttta
    45241 atagtaattg gaaagatatt catattggta tttatgatac aaaactagga gattctttaa
    45301 agtatatcac taatgaatat attgaaaatc tggaaagggt aaaatatgat tatcgtgaat
    45361 taaaaaatat agaaaatcaa actgatggta tgtgtatttt agcaataagg cagaattaca
    45421 aggcattaga gtatgtgaaa agtcaaactg aagaattatg tttagaagca ataaagtata
    45481 attataaagc acttgaatat gtaaaagagc aaacagaata tatatgtctt gaagctataa
    45541 aaaaggattg taatgcactc aagtatgtac gaaataaaac agaagggctt attataaaag
    45601 taatacgtca ttctaccaat atagatgttg taagtatact aaaggcttta gagactcaaa
    45661 caagaagaat atgtttagaa gcaattaaaa aagatggcag gtgtcttgca tacgttagag
    45721 aacagagtga agaattatgt atagaggcca ttaaacaaaa ttataaagca ttaaaatatg
    45781 tagaaaatca aacggaaaaa atgtgtatag aagctgttaa acaaaatggt atggcattac
    45841 aatatgtaaa taaacaaacg gataaaatat gtatagaagc tgtcaaacaa gatggaagaa
    45901 gtctacaatt tgtcgataat aagacagaag aaatatgtat aaatgctata agatatttaa
    45961 ataaaaaata taatattaaa gatgtgctgt gttacgtaga taattataca gaagatatgt
    46021 gtatagagat tgtaagacaa aatggaaaaa tgcttatgta tataaaaaat caaacagaaa
    46081 aaatatgtat tgaagcagta aaagagaatt ataagtctct taagtatgta aaagagcaat
    46141 ctgagagaat atgtaaagaa gcattgaaac aaaattataa agcaaaagag tatgtaaaaa
    46201 ttgccattga tgattgtata taaggtgtat ctacaggcat caataatgaa agataaaaaa
    46261 agataaagac aagtacttta taataatctg ggcttatact ataattaatt aagcagtgat
    46321 ataaattcac atgacgatta tatcaaaatg gagatgaatt aatggcaaaa atatatttag
    46381 aaaatgaaaa taaaactaga gaaataggat ataaattagg taaactttta aaagaaggta
    46441 gtgttatctg tttagtagga gatttaggag ctggcaaaac tacaatgaca caaagtttgg
    46501 cagattcatt agggataaaa gattatataa caagtcctac ttttactata ataaatgaat
    46561 atgaaggaaa aatacctttg tatcattttg atgtttatag aataggcagt agtgatgaaa
    46621 tgtatgatat tggttatgat gaatatgtaa attcaaatgg aatctgtata atagaatggg
    46681 ctaatctaat agaagacata cttccaaaag aatatttgaa tatagaattg agatataaag
    46741 atgaaggaag agaaatgata ttaactccaa aaggagagtt ttataaagaa atagttgagg
    46801 agttgattaa ataatgaaaa tactaggtat ggatacatct tctatggcag caagcgtagc
    46861 agttgttgaa gatgataact taatatgtga atttacagcg aacaacaaaa aaactcattc
    46921 gcaaaagctt atgccaatga tagaaaatat gttgagcatg agtgatttaa gtataaaaga
    46981 tatggattta ttagctgtat gtataggtcc aggctcgttt actggactta gaataggtat
    47041 ggccacagta aaagctatgg ctcatgtaaa taatatacca ataatagcag taaattcttt
    47101 agaatctcta gcaaataaca tgaatttttg tgatagaaag atatgttgta tattagatgc
    47161 tcagaaaaat caagtttatt cagctaaata caagtttgaa aatggagaga tgatagaatt
    47221 agatggtgtt gatgttatag agtttgatgc tttagtagag gaaattgtat caactaatga
    47281 agaatttata atggttggag aagctgtata caaatataaa gataagctag agaatataga
    47341 aaatataaag ataccttcac cagctaataa tgtatctaaa gcaggaagtt tatgctcttt
    47401 agcattaaat aaatataata aaaatataga tgtacatact tgttatacaa taaatcctat
    47461 gtatatcaga aaatctcaag ctgaagtaca atatgatgaa aaaatgaaga ggctaaataa
    47521 tggaagataa tataaattta atagtaaatg atataaaaat agaagaaatg accattgaag
    47581 atatagatga agtttttgaa gtagaaaaaa attgttttga agattattgg tcaaaagagt
    47641 cttttagaaa agagttatct aatgaagtag caaggtatat agtagctaag ttagatggaa
    47701 aaattgttgg atatgtggga atttggctta tacttgatga aggacatata aataatgttg
    47761 cggttcatag tgactataga gggaaaaaaa taggggataa attgataaaa ggcatagttg
    47821 atttatgtaa agataataat attgcatcta tgacattaga agttagagca tcaaataaaa
    47881 tagcacaaaa tttatataga aaatatggat ttaaaatggg tggaataaga aaagaatact
    47941 acagtgataa taaagaagat gcaattataa tgtggaacca attaaaagag gtgtagagtt
    48001 tatgagtgat ataataacat tagctataga gagtagttgt gacgaaacag ccgcatcagt
    48061 tttaaaaaat ggtagagaag tactttcaaa cataatctct actcaaatcg agacacataa
    48121 aaaatttggt ggtgtagttc cagaagtggc ttcaagaaaa catgtggaaa atattgatat
    48181 agttgttcaa gaagctttag acaaagcaaa tatggatttt aatgatatag accatatagc
    48241 agttacatat ggacctggac tagtaggtgc tttactggtt ggtctatctt atgctaaagc
    48301 acttgcctat actttgaata ttccacttgt aggagtaaat catatagaag ggcatttaag
    48361 tgcaaactat atagagcata aggatttgaa acctcctttt ataacattaa tagtatctgg
    48421 aggtcatact cacttggttg aagtaaaaga ctatggaaag tatgagattt taggaaaaac
    48481 aagagatgat gcatctggag aagcctttga taagatttca agagcaatga atttaggcta
    48541 tccaggaggt cctattattg ataatctagc ccaaaaggga aataagcatg ctatagaatt
    48601 tccaagagcc tatttagaag aagatagtta tgattttagt tttagtggat taaaatcttc
    48661 tgtattaaat tatctaaatg gaaagagaat gaagaatgaa gaaatagtag ttgaagatgt
    48721 agcagcatct ttccaagagg ctgtagtaga ggttttatct actaaagcac taaaagcagt
    48781 aaaagacaaa ggatacaata tcataactct ttctggtggg gttgcttcta attcggggct
    48841 tagagctaaa ataacagagc ttgctaaaga cagtggtatt actgttaagt atcctcctct
    48901 aattttatgc acagataatg cagctatgat agggtgtgca ggatattata attttataaa
    48961 cggtaaaacc catgatatga gtttaaatgc agttccaaat ttaaagataa atcagtagag
    49021 taagataaat ttgtaaatat aaaagtattg tttcaaaaaa gtaagtagaa gtaaaattaa
    49081 atacaataaa aattaatata gtgtatatta aaacttgaag taaaactatt tataatcttt
    49141 atgtcccaat gaattgcaac acattttagg atataaaggt tgtctttggc ttagatttgc
    49201 ttcaagttta attttttctg tagaaagatt attttaaaaa gtgggtaata tacccttttt
    49261 tttcattctt aaaaagtttt atactaatta tagaaagatt aaggagggga agaaatgagt
    49321 caaagtaaag aagacaaaat aagaagtatt ttggaagcaa aaaatattaa atcaaatttt
    49381 caaaataaag aaaatttaaa tgaatttaat gaaaaaaaag caagtaaaag agcagaagac
    49441 ttattagatg tatattataa tacattatct actgctgata tggaatttcc atattggtat
    49501 aatagagaat atagaaaatc agatggtgat ataccagtag ttagaagagc taaagctctt
    49561 aaagctgctt tttcacatat gacaccaaat ataatccctg gtgaaaaaat agtaatgcaa
    49621 aagacacacc attatagagg ctcttttcca atgccatggg taagtgaaag cttctttgtt
    49681 gctcaaggag aacaaatgag agaagaggca aagaaattgg ccagtaacac agctgatgag
    49741 cttacaaaat ttgggtctgg cggaggaaat gttactgaaa gttttggaaa tgtcgtttca
    49801 atagctggta aattcggaat gagaaaagaa gaagtacctg tacttgtaaa aatggcaaaa
    49861 gaatgggttg gaaagtctgt tgaagattta ggttttcact atgaaaaaat gatgccagat
    49921 tatgatttaa aagaaaatct aatgagcacg cttatatgca tgtttgattc agggtataca
    49981 cttcctcaag gtagagaagt tataaattat ttttatcctt taaattatgg attagatgga
    50041 attatagaaa tggcaaaaga atgtaaaaag tcagttgcag gaaatgcatc tggagatggg
    50101 cttattggta tggaccgtct atatttctat gaggctgtta ttcaagttat tgaaggatta
    50161 caaacttgga ttttaaatta tgcaaaacat gcaaaatatt tagaaagtat agagacagat
    50221 ttagaagcta aaaaagaata ttcagattta gtggaaatat tagaacatat tgcacataaa
    50281 caacctcgta catttaggga agctcttcag ttgacttata caattcatat agcatcagta
    50341 aatgaggatg ctatatctgg tatgtctata ggtcgtttcg gtcaaatttt atatccttgg
    50401 tatgaacaag atatagaaaa aggattaatt acaaaagaag aggttatcga attattagaa
    50461 ctttatagaa taaaaattac ttgtattgac tgttttgctt cagcgggcgt aaatggagga
    50521 gtactatcag gaaatacgtt taacacttta tctataggtg gattaagaga agatggttct
    50581 acaggagcta atgagctaga agaattattg ttagaagcaa gtatgagatg tagaactcct
    50641 caacctagtt taactatgtt atatgatgaa aagcttccag aagatttctt aatgaaagct
    50701 gctgaatgta caaagcttgg ttctggttat ccagcatggg taaacaattc aaatggaaca
    50761 acatttatga tgaaacaatt tgctgatgaa ggtatgactg tagaggaagc aagagcattt
    50821 gcgttaggtg gatgtttgga aacgtctcca gggtgctgga aacagttaac tttaaatggg
    50881 aagacatact ctattgcagg tggagcaggt caatctgctg gttctggagt tcactttata
    50941 gctaatccta aaatcttaga acttgtactt atgaatggta aagactatcg tatgaatata
    51001 caagtgtttg agcctcataa taagccatta gatacttatg aagaagtcat agaagtattt
    51061 aaagattatt ataaacaagc aataaatgtt ttagaaagag caaataatat tgagttagat
    51121 atatggagaa aatttgatac ttctataata aattcactat taaagccaga ttgtctagat
    51181 aaaggtcaac atataggaaa tatgggatat cgttataatg caacattaaa cgtagaaact
    51241 tgtggtactg ttactatggt caattcattt gcagcactta agaaacttgt atatgatgac
    51301 aaagcattta cgatagagga aatgaaggat gccatattaa ataattttgg ctttaaagat
    51361 gcattagaag taggaaatta ttctatggca gaccaagtaa aagtagataa gactgggaag
    51421 tatgatgcta tttataaggc gtgtcttgat gcacctaaat atggaaataa tgatttgtat
    51481 gcagacaata ttcttaaaaa ctatgaggta tggttatcaa aagtatgtga agaagcacaa
    51541 tctttatatg ctaagaagat gtatccttgc caaatatctg tttctacaca tggaccacaa
    51601 ggagctgcta ctttggctac tccagatggt agattaagtg gaacaacata ttcagacggt
    51661 tcagtttctg catatgcagg aacagataaa aatggagtat atgcattatt tgaatctgca
    51721 actatttggg accaagcggt agttcaaaat tctcagatga atttaaaact tcatccaaca
    51781 actataaaag gacaacaagg aactaaaaaa ttattagatt taacaagaag ttatttaaga
    51841 aaaggcgggt tccatattca atataatgtt gtagattcag aaacattaaa agatgcacaa
    51901 aaaaatcctg acaattatcg tcaattaatg gtacgtgttg ctgggtttac tcaatattgg
    51961 tgtgaattag gtaaaccaat acaagatgaa gtaattgcta gaacagagta tgaaggggtg
    52021 taaaatatga gaaagcatag tgattgtatg aatttttgtg cagtagatgc aaccaaagga
    52081 atttgtagat tgtcaaaaca aatgattaat ttagatgatg aagcatgtcc agagataaaa
    52141 gtaatgccaa aatgtaaaaa ttgtaaaaat tttgttgaag ctaatgatga aggtataggc
    52201 aagtgtgttg gtctagaaaa ggaagactgg gtatattcaa cattgaatgc aattacttgt
    52261 gaaggacatg tgtttaatga gtagtcaaaa gaaattagaa ggtatgattt ttgatgtaca
    52321 aagcttttca gttcatgatg gtccaggttg tagaacaact gtatttttaa atggatgtcc
    52381 actgagttgt aaatggtgtg caaatccaga aagttggact gtaagaccac atatgatgtt
    52441 tagtgaatta tcttgtcaat atgaaaatgg atgtactgtg tgtcatggta agtgtaaaaa
    52501 tggtgcattg agctttaatc ttgataataa gccagttata gattggaaca tctgtaagga
    52561 ctgtgagagt tttgaatgcg tcaactcatg ttattataat gcgtttaaat tatgtgcaaa
    52621 agcttatact gtagatgaac ttgtgcaggt aattaaacgt gattctaaca attggagaag
    52681 taatggagga gtaacattta gtggaggtga gccactactt cagcatgaat ttttacatga
    52741 agtattatta aagtgtcatg aggtaaatat acacactgcc attgaaacga gtgcatgtgt
    52801 atcaagtgaa gtttttaata aaatatttga agatattgat tttgcattta ttgatataaa
    52861 acatatggat agagaaaagc acaaagaaca aacaggtgtg tataatgatt taatactaaa
    52921 aaatatatca aaccttgcaa attctgattg gaatgggaga ttagtactta gagtaccagt
    52981 tatctctggg tttaatgata gtgttaaaaa tataagtgat attatatctt ttatgcacaa
    53041 aaataattta gtagagatta atctattacc atttcacaga ctaggtgaat caaagtgggt
    53101 tcaattaggt aaagaatatg agtattctga taagggtgat gttgatgaag gtcatcttga
    53161 agaattacaa gatatatttt tggataatgg tatagcttgt tatgttggtc atgagacagc
    53221 tttctaaaat caaatacaag ttttaattaa aaaaggatgt tgtactaaaa gctagagtca
    53281 catccttttt tatgaggttt ttatgtataa agagttataa tatattttac taatttaaga
    53341 taaaaataat aattttttat aggtggaatc tttgcttgat atagaaatta ataataagat
    53401 tattccactt gttccctcta aaaaggatgt gttttccatt gtttctaaat tactaaatgt
    53461 tttaaagctg tatcttaatg ataaatcaaa caattgaaat atttcatcta aagttttttc
    53521 aaggttgtat agataaacat tatcatttgt ttttttgtac actgatgtca ttatagacaa
    53581 aatttaataa ctatccttta tattcttttg taaatagaaa tggaacataa aaaattaaag
    53641 aaaccataga tactattaat atgtcagaat aagtaataat tgactcttca acatttgtta
    53701 taagaaaagc gctattattt aaaatatgaa ttatagcaca aaaccagaca tttttagttt
    53761 tcatataaag atatcctaaa aatattgcaa ttccaactat atgtattgaa cgtaatatta
    53821 atcctaatat tggtgtttca ggtgtatata atgtaaatat tagtggtaag tgccacaaac
    53881 tccaacacat acctaatatt ataactccta gttttttacc aaacctatca aaaaaaatat
    53941 tctgtaaaaa acctctccaa gcatattctt cactaaaaaa aatataaata gtagttaatg
    54001 atgttattgg agtaaatata aattttatga tcccgctata actaggttga gttccttgta
    54061 gtattaagag aaatgatgtt ggaacaatta cagaaatcat aaagtaaata attaacaaag
    54121 aacctgcttt aatatttttt acgggatata aattttttgt atttgatgaa taaattataa
    54181 ttgataaact acttataaaa gttaatatta ggtttataat tgtaaattca ctattattta
    54241 ttagatttag caacctaaga ataattaata atgaataaat aagaaaaaat aatatgatta
    54301 gtgaataaaa tttatacata tcattattta atccttcagt ataaaatt
//
LOCUS       DBGJFK010000021        53461 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.021, whole genome shotgun sequence.
ACCESSION   DBGJFK010000021 DBGJFK010000000
VERSION     DBGJFK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53461
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.021"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(119..457)
                     /locus_tag="ACOIAP_001477"
     CDS             complement(119..457)
                     /locus_tag="ACOIAP_001477"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638365.1"
                     /translation="MKIKRILMVCFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKNVPTLAEKDKSNSKSKNKEDETEDDLYVRKTVGVLLDTENLNNESYNNNVLS
                     ALKRADEDFD"
     gene            complement(583..1587)
                     /locus_tag="ACOIAP_001478"
     CDS             complement(583..1587)
                     /locus_tag="ACOIAP_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2638366.1"
                     /translation="MRFKRILIFILTVAMTAGMLVGCDSNQSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFETGFKEGVKFSNSSIKDISVEYADVFKDRK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIGAVRTKNKKVIATNKDQHELAPENVISSI
                     VKDFENSTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVSKNNK
                     "
     gene            complement(1875..2723)
                     /locus_tag="ACOIAP_001479"
     CDS             complement(1875..2723)
                     /locus_tag="ACOIAP_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGZ2638367.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEKEYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEGREILYIAGSATATGTYQSAVM
                     AKNDVEGKIYTYDSNLLCMGTGLLVIKAGELASEGKTVDEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMEDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(2758..3228)
                     /gene="trmL"
                     /locus_tag="ACOIAP_001480"
     CDS             complement(2758..3228)
                     /gene="trmL"
                     /locus_tag="ACOIAP_001480"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HGZ2638368.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPETLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(3422..4279)
                     /gene="nth"
                     /locus_tag="ACOIAP_001481"
     CDS             complement(3422..4279)
                     /gene="nth"
                     /locus_tag="ACOIAP_001481"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGZ2638369.1"
                     /translation="MKNVNLKEINKKEVIDKEEINKKGIDKKDVTEKEKINKKSEHDK
                     KTKNSSSSKDTQKLSKGIKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNYGTAF
                     ELLIATILSAQCTDVRVNKVTSELFKKYNTAKDFANLSIEEISKEIKSCGLYKSKSQK
                     IKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSN
                     RIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCN
                     YYKELNETK"
     gene            complement(4477..6714)
                     /locus_tag="ACOIAP_001482"
     CDS             complement(4477..6714)
                     /locus_tag="ACOIAP_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2638370.1"
                     /translation="MKYNNTSEINPLDCILGQERAVEAMELGLKINNPAYNIYIAGES
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQDYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEGNEEGIARFIASQCDKNNLRHFTKSAVEEVVKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVPIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVQDGKFKIYTVERVEEAIEILTDVKFEEIRKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(6820..7734)
                     /gene="queG"
                     /locus_tag="ACOIAP_001483"
     CDS             complement(6820..7734)
                     /gene="queG"
                     /locus_tag="ACOIAP_001483"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HGZ2638371.1"
                     /translation="MNNRELKEFCNLIGLNCVGVAGVDKYDNLENILKDRYKKGYLTG
                     MEEPIIENRINPRNIMEDANSIIVCAFPYYINRQEKNKNSNLSKYCHGKDYHIVVKKF
                     LQQICDYISKKVTDFKYKIFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSQE
                     EKAVLKSGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGKNIIKRNMEIILDKYND"
     gene            8492..8896
                     /locus_tag="ACOIAP_001484"
     CDS             8492..8896
                     /locus_tag="ACOIAP_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HGZ2638372.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYNISYNIFEK"
     gene            complement(9130..10125)
                     /locus_tag="ACOIAP_001485"
     CDS             complement(9130..10125)
                     /locus_tag="ACOIAP_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGZ2638373.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADDVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(10408..11244)
                     /locus_tag="ACOIAP_001486"
     CDS             complement(10408..11244)
                     /locus_tag="ACOIAP_001486"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008833 - deoxyribonuclease IV
                     (phage-T4-induced) activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HGZ2638374.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     NEKDIIKFQEIRKANNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIDRLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(11727..12290)
                     /locus_tag="ACOIAP_001487"
     CDS             complement(11727..12290)
                     /locus_tag="ACOIAP_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2638375.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(12388..13317)
                     /gene="glsA"
                     /locus_tag="ACOIAP_001488"
     CDS             complement(12388..13317)
                     /gene="glsA"
                     /locus_tag="ACOIAP_001488"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HGZ2638376.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(13891..15558)
                     /locus_tag="ACOIAP_001489"
     CDS             complement(13891..15558)
                     /locus_tag="ACOIAP_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HGZ2638377.1"
                     /translation="MKKINLKIEGKDKEYSLEENSHGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEVDVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDNNKRVILIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLED
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(15632..16387)
                     /locus_tag="ACOIAP_001490"
     CDS             complement(15632..16387)
                     /locus_tag="ACOIAP_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGZ2638378.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSDLCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELRGFDIRYFNLHLGYV
                     MTNRVRRNRDKYLENSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDDYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLDNIVGEG"
     gene            complement(16397..16933)
                     /gene="lepB"
                     /locus_tag="ACOIAP_001491"
     CDS             complement(16397..16933)
                     /gene="lepB"
                     /locus_tag="ACOIAP_001491"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGZ2638379.1"
                     /translation="MNETIKEEIVEWIKIIITALFLAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(17099..17635)
                     /gene="lepB"
                     /locus_tag="ACOIAP_001492"
     CDS             complement(17099..17635)
                     /gene="lepB"
                     /locus_tag="ACOIAP_001492"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGZ2638380.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDVDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHAI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(17735..19045)
                     /locus_tag="ACOIAP_001493"
     CDS             complement(17735..19045)
                     /locus_tag="ACOIAP_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGZ2638381.1"
                     /translation="MTKLPKEFLEDVEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLGLFDLNQISWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINVSRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSHAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRRENLYLLPK
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKETSGVIKNHYPKGLRKVF"
     gene            complement(19124..19840)
                     /locus_tag="ACOIAP_001494"
     CDS             complement(19124..19840)
                     /locus_tag="ACOIAP_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HGZ2638382.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVILLWKINLDKLE
                     KYMNNSKKVFFGNLRKKKKK"
     gene            20077..21348
                     /gene="sleC"
                     /locus_tag="ACOIAP_001495"
     CDS             20077..21348
                     /gene="sleC"
                     /locus_tag="ACOIAP_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic germination protein SleC"
                     /protein_id="HGZ2638383.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTTYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRFFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVRIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(21822..22478)
                     /locus_tag="ACOIAP_001496"
     CDS             complement(21822..22478)
                     /locus_tag="ACOIAP_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638384.1"
                     /translation="MKKGDFIWSGILICIIAVLAIPSSREVFMEATGAHPYIGGFFKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGIVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(23679..24089)
                     /locus_tag="ACOIAP_001497"
     CDS             complement(23679..24089)
                     /locus_tag="ACOIAP_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638385.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEKDL
                     EKIKTEGLKIMKPITIKNEDGSQISIAYNYAAID"
     gene            complement(24305..25663)
                     /locus_tag="ACOIAP_001498"
     CDS             complement(24305..25663)
                     /locus_tag="ACOIAP_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HGZ2638386.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNASTENYTLKKAGDSTGKNNSDKFEIMSSIE
                     NIMMLEMLGILSFIVTIIFSILLCFRYIKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGIGLVFATENKEINEVESF
                     GLTKNEKSVLSISSDSTELYTPKVDSNISVSMSKVSMNKSSESKSYEDISMNKVRNTE
                     NYSEVSVEKSSKSNDYEDVLYTPSAEYSIQKNNYNEGVLVISRKGNLLAVNNIQYRTS
                     IK"
     gene            complement(25674..26033)
                     /locus_tag="ACOIAP_001499"
     CDS             complement(25674..26033)
                     /locus_tag="ACOIAP_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2638387.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(26238..27017)
                     /locus_tag="ACOIAP_001500"
     CDS             complement(26238..27017)
                     /locus_tag="ACOIAP_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGZ2638388.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKMGDIFVNGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICENKDNLGVFKSMSASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
     gene            complement(27479..28090)
                     /locus_tag="ACOIAP_001501"
     CDS             complement(27479..28090)
                     /locus_tag="ACOIAP_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638389.1"
                     /translation="MKMVKKLILSSIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGIADALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANNLVKSYVTDEKNYDKKEKEVQDDMAK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(28182..29171)
                     /locus_tag="ACOIAP_001502"
     CDS             complement(28182..29171)
                     /locus_tag="ACOIAP_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HGZ2638390.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNIPV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGVGGQGEPQLEAMIEARNLDEVRVFSR
                     NKENREKFVEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVFNGNLVKKG
                     ALISAVGSYMPDMQELCPICLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGMDWKW"
     gene            complement(29239..30096)
                     /locus_tag="ACOIAP_001503"
     CDS             complement(29239..30096)
                     /locus_tag="ACOIAP_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HGZ2638391.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLKNASIN
                     LNNKEAVSVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSNKI
                     VERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSIKV
                     RYYTYSGGAHGFYQDTAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELEKK
                     DEENIGIYNFKGIKENQNFYLQDDNLVIYFDLYDITPYAAGIPEFSINKKLISSMLKP
                     EYVDLFDLK"
     gene            complement(30202..30798)
                     /locus_tag="ACOIAP_001504"
     CDS             complement(30202..30798)
                     /locus_tag="ACOIAP_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CheB methylesterase domain-containing protein"
                     /protein_id="HGZ2638392.1"
                     /translation="MGRFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGCQMKLCADKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(30838..31641)
                     /locus_tag="ACOIAP_001505"
     CDS             complement(30838..31641)
                     /locus_tag="ACOIAP_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008983 - protein-glutamate
                     O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HGZ2638393.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIERKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSIFPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSNTKYKYVKPAIYKR"
     gene            complement(31677..32117)
                     /locus_tag="ACOIAP_001506"
     CDS             complement(31677..32117)
                     /locus_tag="ACOIAP_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HGZ2638394.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPEADYNERTCIIITKVDEYQVGIIVDRVIDVIPI
                     ENLNLLATTNSNNININKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(32130..34232)
                     /locus_tag="ACOIAP_001507"
     CDS             complement(32130..34232)
                     /locus_tag="ACOIAP_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HGZ2638395.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEDYVSTLELSSSMKSKDNASLESTDEIEVIDLNFAYREG
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFLDFYPKDVETNAESTEYIKNYGFYIQ
                     FVAKEDNSIVYKIIEENLYVKEYINISKKEIEMKSTSNNNEVENKLKDSNKVSKSYKN
                     NYTEDELQEDVLNEKTDIEKDGLSGENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKSTRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLTEPFMHLIRNAMDHAIEPIEERIAKGKKEVG
                     KIVLSAENLGGEAVISISDDGRGIMKDKILAKAKEQGLLKHQTNEYTDEEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKPDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEENKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMHGNMIIIENENKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(34403..36106)
                     /locus_tag="ACOIAP_001508"
     CDS             complement(34403..36106)
                     /locus_tag="ACOIAP_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HGZ2638396.1"
                     /translation="MKREVKLSKLAIVLLVIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQNIIFSSDYINSQEKMDSLI
                     NEFQEDIVARSNAKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVDFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVKIAKETANALELVVNGVEKTTDYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKEREVRESSW
                     V"
     gene            complement(36132..37091)
                     /locus_tag="ACOIAP_001509"
     CDS             complement(36132..37091)
                     /locus_tag="ACOIAP_001509"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2638397.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKALTKDNFKVKKAFNAIEAKK
                     FIEEFIPDIILLDIILPDNSGFDFCKEVKSNARTADIPIIFITSKNADTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTIISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEDAKILSERIRKEIKEFDFNYKENKIKCTITLG
                     VVEVNSNISLEENISLADKVMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(37227..37745)
                     /locus_tag="ACOIAP_001510"
     CDS             complement(37227..37745)
                     /locus_tag="ACOIAP_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HGZ2638398.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMITNCMYIVVTEIKDLVVGFV
                     VDRVDDIISLEKSEISPPPRVTIEYSDYFVSGIGELDGKVITLLDLEKLLTDKDEILI
                     DELINGFDCTIM"
     gene            complement(37788..38255)
                     /locus_tag="ACOIAP_001511"
     CDS             complement(37788..38255)
                     /locus_tag="ACOIAP_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HGZ2638399.1"
                     /translation="MNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGMLHVMLP
                     YSKDAINIENKYKFADTGIKELIKSMENIGANRIYIKAKIAGGAQMFLGNSNSAIASI
                     GHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELIVDSINKGKKKL"
     gene            complement(38270..38917)
                     /locus_tag="ACOIAP_001512"
     CDS             complement(38270..38917)
                     /locus_tag="ACOIAP_001512"
                     /inference="COORDINATES: protein motif:HMM:NF016398.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HGZ2638400.1"
                     /translation="MNLIIEGGVYIINYLELDDAHIDALREIGNIGSGNAITSLASMI
                     NSNVEVLIPMVKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLML
                     SSLFNKEEVPLDDIEEIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVG
                     AVLNVPMIRFSDVGDKVLFVENKFKMSDNYFTSHILMIPEMSSLREILVKLGLEI"
     gene            complement(38952..39314)
                     /locus_tag="ACOIAP_001513"
     CDS             complement(38952..39314)
                     /locus_tag="ACOIAP_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGZ2638401.1"
                     /translation="MGNKILIVDDAIFMRMIIKEALGKSGYNNLVEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVDAIKLGALDFI
                     VKPFKTETLVKVVNNALK"
     gene            complement(40049..40546)
                     /locus_tag="ACOIAP_001514"
     CDS             complement(40049..40546)
                     /locus_tag="ACOIAP_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGZ2638402.1"
                     /translation="MNYEIVEISEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKSDKTIGLYTDYQGDFTSPYNFVACCEVNSNSDKDKNLEELNTNNTVGEIII
                     SKVIPAGKYAKFVIAGGQKEVGDFWLEFWQMDFDRTYVSDFEEYQSNTFDTNKHEIHI
                     YIGIK"
     gene            complement(40703..41614)
                     /locus_tag="ACOIAP_001515"
     CDS             complement(40703..41614)
                     /locus_tag="ACOIAP_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638403.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMMKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNIINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKEEVFSRKVIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDNTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLKELSKIYSL"
     gene            42341..43192
                     /locus_tag="ACOIAP_001516"
     CDS             42341..43192
                     /locus_tag="ACOIAP_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HGZ2638404.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVIGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKNTKEI
                     KSTKGEC"
     gene            43196..43666
                     /locus_tag="ACOIAP_001517"
     CDS             43196..43666
                     /locus_tag="ACOIAP_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638405.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            43679..44989
                     /locus_tag="ACOIAP_001518"
     CDS             43679..44989
                     /locus_tag="ACOIAP_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HGZ2638406.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYNNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKEGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHSSDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVKITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIVPAK
                     AMALTVVDLLFDNAKNAKDILDAFTPVMTKEEYLTFLEKHDKTL"
     gene            45544..47085
                     /locus_tag="ACOIAP_001519"
     CDS             45544..47085
                     /locus_tag="ACOIAP_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HGZ2638407.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SVVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAKLDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMIFNIPLGPGIL
                     PSYSM"
     gene            47120..48226
                     /locus_tag="ACOIAP_001520"
     CDS             47120..48226
                     /locus_tag="ACOIAP_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGZ2638408.1"
                     /translation="MLDKNRLINNFIDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPVLDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPENLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDRVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGIVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(48533..49819)
                     /locus_tag="ACOIAP_001521"
     CDS             complement(48533..49819)
                     /locus_tag="ACOIAP_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGZ2638409.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDNDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFKLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRYSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAISENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(49942..53040)
                     /locus_tag="ACOIAP_001522"
     CDS             complement(49942..53040)
                     /locus_tag="ACOIAP_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2638410.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKALRINDISNMK
                     CYEAIQGRDSPCEFCTNSILKEDGYYVWENTNTLINRHFILKDKLIKWEGKLARIEIA
                     LDITEKENISKSISEKLEIKELLVGCIKHLITESSFSDAVDLVLSSIGKFHKADRAYV
                     FEVSEDRKKVINTYEWCNEGVDEQKQLLTNLDIKELKNWFLLFKQKGFIIIDDVEDIK
                     EEHPMEYEILKPQKIKSLMASSLKEDDKIIGFIGVDNPRKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTSAYNRNRYIKYIDTFQKDKVKSIGVVFIDINGLKDIND
                     NFGHASGDAIIMSVSVMIQKYFHSYYVYRIGGDEFVVLCEDISKQLFEELVSWLTEEL
                     KDNMECSAAVGSIWSEDDIDIHKLIKVADERMYQDKKRYYNKIELRNNEMKVVSDLSD
                     STNNISLKCRDLDNEVYFDDLMIKGYSKAYEKLAYNTYDIILSICMDTNLITPIYQSE
                     SNILNFPIKENIEKIFSYIKKHLIHPDDIILFDDNLLLKSIDSPNNSKQGDLELNFEY
                     RHLGIDEKYHWALLYILKISSKNNLGEKQTHILVAIKNIDYLMQIHKNQKDTLTGLYN
                     YESFCEQTSLMLKRYPGKRYAIIMMDIDKFKVINDIYGIRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDREIHKVIYNIKNNLNRKKFEYMLVPCFGVYKILDNH
                     IPITSACEMAGYAHKKVKKQSINHYIFYDDTIRNDALEEKHMEREMEYALENGQFHVY
                     LQPKYNLNTNKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIKLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYGIPKSFLELELTESLFIKN
                     IKLFTKVIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNGEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSDDFEKLLY
                     QK"
BASE COUNT        17474 a         9407 c         5555 g        21025 t
ORIGIN      
        1 cagcaattca agtagtattg gataggttct atcctatctc tacatataag tttccctata
       61 tgctgactat tttagctact aactcatgac taaagtcacg agtgtgcgta gctatttttt
      121 aatcaaaatc ttcgtcagcc ctttttaagg ctgatagtac attattatta tatgattcat
      181 tatttaagtt ttcagtatct aataatactc caacagtttt tcttacatat aaatcatctt
      241 ctgtctcatc ttctttattc ttacttttac tatttgattt atccttttct gctaaagtcg
      301 gtacattttt agactcactc tgttttgatt tagcactatc tatattagaa ttattcttat
      361 ttactttatc aaacccaaaa tcaaaattac atatagctaa tataaaaatt gtaaaaacta
      421 ccacaaagca aaccatcaat atccttttta ttttcacaaa attcactccc tgatttagat
      481 aggcattacc tacctctaca tatgcctttc tatatatgtc tattataaca gccagttcaa
      541 ctcataacta aagtcataag tattcctgga tattatagaa gattatttat tgttcttact
      601 aacatattct aacacatctg gaggaatatt ttgagaacta ttttgggcaa gcccagtact
      661 tccagactta actgtatttt ctataacttt tccaccttta taatttcctt ttacaaagct
      721 ttgtatcaaa ttataagtag aattctcaaa atcttttaca atagaactga taacattttc
      781 tggagctaac tcatgttggt ctttatttgt tgctataact tttttatttt ttgttcttac
      841 tgcacctatt acagcttttg aatcatcttc agtagtagaa aaaataatat ccactccatt
      901 atccatcatc tttttagcta tagattctac tgattttcta tctttaaaaa catctgcata
      961 ttcaactgaa atatctttta tgctactatt agaaaactta acaccttctt taaaacctgt
     1021 ttcaaatttg tctctactcg aactctttgt tccacctata aaaccaacct tatcgctttc
     1081 agtcatcttt ccagcaatta atccagctag gtatccagat ttattatctt cataagaaat
     1141 tgaagttata ttagaaggtt gcttgtcata ctcatagtct ataattgcaa attgttgctt
     1201 tggatatttc ttggctacca tctccaaagg ttttgcaaat ctagctccta cagctataat
     1261 taaatcgtaa ttgtcattac ataaaatatc tatactatta gaaaaagttg atgaatcatc
     1321 tgattccact ttgtttgtgt ctatattaag tttcttttga gcattgttta atgctaataa
     1381 agctgaatta ttcatagctt cattatttgt tccttcaata tctagtatca tagatacaga
     1441 tttttttgaa ttacttttgt cgcttatatc acttttatta tctttgctag aactaggatt
     1501 attactttga ttactatcac atccaaccaa cattccagct gtcattgcta cagttaatat
     1561 aaatatcaat attcttttga aacgcattaa atttcactcc tcatacattt atgatatttt
     1621 tactcttatt tacttttaca tcctatttat aattttttta tatacaattt acaagtacat
     1681 tttgaaaatt ttttaataaa tattactata aaaaagtgtg caatagactc ttatctattt
     1741 acacacttcc ctacaaacta aatctaataa atcaacactt aattttatcc aaaataaatc
     1801 caatttagca tctcaatatt tagtattcta tcctaattta ataaaaaaat aaataatatt
     1861 acctcaaaat atatttattt attttttaaa catatgatac cagtgacacc aggaccagca
     1921 tgtgcaccta tacacacccc aatttggaaa aatctaattt ctttaggtct taattcatct
     1981 tccataacct tagataattg ttctttttcc ttaaaatcat cactatatcc tatatacaca
     2041 atttggtctg ataaatcatc cccacaattt gattttatca attccatcat cttagaaatt
     2101 acattctttt tccctcttac ttgagatatt tgcgaaacta gtccatctct tatttcaaga
     2161 atcggtttta tatttaatat acttcctatt gctgccttag tagatgatat tctacctccc
     2221 ttttgtaagt attccagtgt atctactgaa aatataacaa aagccttctc ttttaattca
     2281 tccaaaacag gcaatatttc atcaacagtc tttccttcac ttgcaagttc tcctgctttt
     2341 attacaagta aaccagttcc catacaaagc aagttagagt catatgtata tattttaccc
     2401 tctacatcat tttttgccat tacagcactt tgatacgtcc ctgtagctgt agcagaccct
     2461 gctatataaa gtatctctct accctcattt gtatattttt caaaaatttc cttaaattgg
     2521 gcataagtag cttgagaagt ttttggatat acattttctt ctctaagcct tttataaaat
     2581 tcatctccag atatatcaat tctatccttg tattcttttt cctccagtat aactgttaac
     2641 gaaactatat ctatatcata tttatctaac aaatcttttg gcacgtccga taaactgtca
     2701 cagattatct ttagattttt cattaagtat gctcctttct catttaggct tgttaaacta
     2761 cctcatattt gggtatccta tttgtcttaa agcctcgtac actacaatag caactgaatt
     2821 tgataaattt aatgacctag ctttttcaac atctaacata ggcactctaa tacaagtatc
     2881 catatttgct ttcaacaaag tctctggtaa tccctttgtt tctttcccaa atactataaa
     2941 acaattttct tcatatttca catctgaatg tgactgttta gcctttgttg tagaaaaaaa
     3001 gtatttactg tttggatact tttcttgtaa ttcttcaaag ctatcgtaat attgtatatc
     3061 agctatatcc caatagtcaa gcccacatct ttttaggtgt ttatcatcca atgaaaaacc
     3121 cagtggcttt actaaatgta aagttgaacc tgttgctgca caggttctta ttatatttcc
     3181 tgtattttga ggtatttctg gttctactaa cactatattt aatgacattt taatcctccc
     3241 taaatattgc ttctatttat caaattttat cttataaata gaataacaat aatattatac
     3301 tattatataa aataatgtta ataataattt ttatttcatg tatataatag ttttttatct
     3361 aacattttca caagtattat tatatcagaa aatgactctt gtacaactta ctttctaaaa
     3421 gttatttcgt ttcattaagt tctttataat aattacaatc ttcttttatt gggcaacttg
     3481 cacattctgg atttctagct ttacacattc ttcttccatg aaaaattaat acatgatgtg
     3541 agtgtgacca tctttctttt ggtatagctt ccatgagtgc aaattctgtt ttttgaggat
     3601 ttggctcatc cactattcct attctattgc taactctaaa tacatgagta tctactgcta
     3661 ttgctggatg attaaaagcg ttgctaagta caacccctgc cgtttttctt ccaacaccag
     3721 gtaattttat aagcttttct aagctatcag gcacttcacc atcatataat tcacatagct
     3781 gttcagatgt atcctttatt ttttgagatt tgcttttgta aagaccacaa ctctttattt
     3841 ccttactaat ttcttcaata ctcaaattag caaagtcttt agctgtattg tactttttga
     3901 acaactctga agtaacttta ttcactctta catcagtaca ttgtgctgat aaaatagttg
     3961 ctatcaaaag ttcaaaggcc gtcccataat ttaactcaca tttagcatct gggtacaact
     4021 tttctaactc atctaaaatc ttatttacat ctttttcatt tgctgactca tttttaattt
     4081 tagacttact tttaattcct ttacttagtt tttgcgtatc cttactagaa ctactattct
     4141 ttgttttttt gtcgtgttca ctttttttat ttatcttttc tttctcagtt acgtctttct
     4201 tatctatacc ttttttattt atctcttctt tatcaattac ctctttttta tttatctctt
     4261 ttagatttac atttttcata attatccccc tttaaaatac taatttataa aacgctattt
     4321 atacatagtt taatcatatc aacaaaaaat aaacatcaat atataaaaca tacaaaataa
     4381 gaatttaatt tatatagatt tcacaaaaaa agcaaaaact tattaaagtt cttgcttttt
     4441 attatacata aatacccatt aaattctata ataaacttat tcttttgaca cagtttgtat
     4501 cttactgaaa gatattaatt tttcttttac cagtttcctt atttcttcaa atttaacatc
     4561 tgtcaatatc tctatagcct cttctactct ttcaacagta tatatcttaa atttcccatc
     4621 ttgcactgca tcattaactt catctgataa aacgagattt ctttgatttt ttctaggaat
     4681 tatgacacct tgctcaccat ttaacccttt ggttttacat atagaataaa atccttctat
     4741 cttttcactt ataccaccaa ctacttgtat atcacccttt tgatttatag aacctgtaac
     4801 agcaatattt tgtttgattg gtactccact aagagatgat aatagtacat ataattctgc
     4861 agaagatgca ctatctccat ctattccacc ataattttgt tcaaaacaaa catatgcatt
     4921 tagtgacaat agcaaatcct gtgcaaaatt ctcagaaaga tagccgccta atataagcac
     4981 tcctttgtta tgtatagagc cactcatatt tacttctctt tctatattta ctataccttt
     5041 acttcctggg ctagtggtag ctgtaatcct tgaagctcta ccaaaagagt attctcctgt
     5101 acttaagact gacagaccat ttatcactcc tacttttctt ccctctgttt ctattagagt
     5161 aaatccattt tcaattgatt catccatatg tgtttccact ctattgattc tttttctctt
     5221 ttcacttatt gcttttttaa catcacactg ctctgtatac tctgaatttc taaattctgc
     5281 ataagcactt ccttcgatta caacttccat tattttatta aacttagttg atagtttttc
     5341 taaatcaccg gacaatctag tgctaaattt aacaacctct tcaactgccg atttagtaaa
     5401 atgtcttaag ttattcttat cacattggga tgctataaat cttgctattc cctcttcatt
     5461 accttcattt ttatccattt cactatcaaa atctacaaat actttaaaat atttttcaaa
     5521 atcttcatca tatctatata aaatatcata tatatagtga cttccaatca gtactaactt
     5581 aacatctaat ggcatatttt ctggtttaat tgctgtttgt gtttccaata ttactttttt
     5641 agtctgcaaa gtctttttaa gaatttccca agacattgta tattttagta attggtctgc
     5701 ataaagtact aaataaccac cattagccct atgaaatgct cctgataata gttttgtgaa
     5761 atcagtcttt atatttccat ttgcataatc atactctgcc tttccaaata gatttgctgg
     5821 acttgggttt atctctacta caacaggtgc tgattcttta ttttttgaac ttccgttgtc
     5881 tacaaataag ttaattttat atttaataaa atgctcttta tcatacttat cttttaactc
     5941 ttcttcatct aaatagaaca aatacatata ttctattata tctttcttta tattttccag
     6001 ataatcttga atcttatcat aattttcata tttttcacac aatctcttga tatgaggttc
     6061 tactacaagc ttagctatct cttcttcaag ctctaacact gctttttcag ctatttcttc
     6121 taagtttcta attttatata cgacctgtat cgccatattt tctagttctc tcttagcttt
     6181 gtaaaactct tcatcagact catcactttc atcttcctct tctttcaaag ggataaaaac
     6241 tattcccatt ttactctgtt ttaatttaaa tcctttttct tctccatatt tcttaatttg
     6301 cttcaaaagc atatcttttt ctatttcata ttcatccaaa agtttatttt tttctatttc
     6361 aaaattttca ctttcaaaag cattcttaaa atcttccaaa agactctcaa ttaatttctc
     6421 catatctttc ttaagttctc ttccaaaccc cttttctaac tcaactataa taggctctct
     6481 agggttttca aaattatata tatagcacca gtctttatgc gtattttttt tggatgcata
     6541 ttcatttaaa acctttagag cataagtact cttaccagtt ccagattcac cagctatata
     6601 tatgttgtat gctggattat ttatttttaa acctagctcc atagcttcta cagctctttc
     6661 ttgacccaat atacaatcta gtggatttat ttcagatgta ttattatatt tcaatattcc
     6721 cccacctccc catatttaac tttaatgata taatatgact ttcacacaac aagtgttaaa
     6781 gtaaatacac attaaagtat atgaaacaga ctcttattat tagtcattat acttatctaa
     6841 aattatttcc atatttctct ttattatatt tttccctctc cagctaaaag ccctatctcc
     6901 atatctcctt ttaaattctt tatttgaaat attttgtatc tcatcataat ccaaataatc
     6961 tattatattt tctttaaatt ccaaaatatg agttgttggt atttcaacat tatgtggaca
     7021 tacttcttga caaatatcgc atccaaatac ctttttgcca ctctttaaaa cagctttttc
     7081 ttcctgtgac aaatctcctt ttttttgagt tatatatgat aaacatttct taggattcat
     7141 atcataattt cccaatatag catttcccgg acaatatttt acacacttac cacatttaaa
     7201 acagcttttt tctagtggtt tatcttcttc aaacttataa ttatttacta tataccctat
     7261 aaatacgtaa gaaccatatt catcagttat gatattatta tttattccaa aatatcctat
     7321 tcctgataaa taagctaaat acctgtcaac taatggtcca ttatcagcaa atatcttata
     7381 tttaaaatct gttacttttt tagaaatata atcgcaaatt tgttgtaaaa atttctttac
     7441 tacaatatga taatcctttc catgacaata ttttgataaa tttgaatttt tatttttttc
     7501 ttgtctattt atataatatg gaaatgcaca cactattata gagttagcat cctccattat
     7561 atttcttgga ttaattctgt tttcaattat tggttcttcc ataccagtta aataaccttt
     7621 tttatacctg tctttaagta tattttctaa attatcatac ttatctacac ctgctactcc
     7681 tacacaattt aatcctatta aattacaaaa ttcttttaat tccctattat tcataaaatt
     7741 attccttttt aatctattta accttttaat ttatttaact tttttatata ctcgaccttt
     7801 ttacccattt aattttttta tctacttagt ttttttatat actcaacctt tttacccatt
     7861 taatttttta tctgcttagt attttttact tattcaacct ttttacttat ttaatttttt
     7921 tatctactta gtctttttta tttaacttac ttaacacttc tatcctactt agtctttttt
     7981 agatcttcaa ttttttaact acttaactct tttatctact tagccttttt tagctattta
     8041 atgtttttac tcacctagcc tttttaatct attcaatctt ttttacccac ttaacctttt
     8101 tggtttttaa tctaaattct aaaaattcaa atatcattag ttatattttg acattcttcc
     8161 tataattaat gtaagaagat tgattttttc ttatatttaa tattccattt acattactgt
     8221 ttattaagtc tttacttgac ttatattgtt ctcttttttt ctcttcacta aacttatgtt
     8281 cattaatatt gtgataagtt tataatagcc taatatgaat atattcagca tatatcagat
     8341 tttaaaattt gtaaataaaa cacttgtctt atatcactac atccaaagtg gaaaagttca
     8401 caaataagct ctgtaaaaac actttaaata acaatttgct tttaaaccat atacagatta
     8461 taataaatac tgtataagga tggtgaaaaa tttgattaaa ataacaattc caggtagacc
     8521 tattagtaaa tctaatttta aacttcacaa cataaatggt caagcatgga tgccttcaaa
     8581 gggaaaatat tctaagtatc ttgcatacga aaacatgatt gcaggtttta taaaccaaca
     8641 gtatcaagga gaaactgttg aagaaaatct aataacagtc ttgaaattat tcttcccaaa
     8701 taagagaatg ggggatttac ataattatcc aaaaagtatt tgtgatggta ttgaaaaaag
     8761 tggaataata aaaaatgata aacaactcaa gccagtactt ttatttgatt ttatagataa
     8821 agataaccct agggttgaaa ttgaacttta tccagtatct aaatataata tatcctacaa
     8881 tatttttgaa aaataaagat tttgtatgtt attcgccatt atattgatgc tctagtattt
     8941 gaaactatac taatacaaca aataatattt gtgttatatc tatactcacg caaatattta
     9001 ataagtatta aacaaatatt aaatttatat aatgcctata actatgtaaa tttaatattt
     9061 gtatataaga ccacatataa taaaaagaaa tcggagtaaa tttactacac cgatttcaat
     9121 aaacaaaatc tatcctagtt tttcgacaac agtcttcagc atttctctta taggaagttc
     9181 atatggacat cggctctcac aaagcccaca gtcaatacac tcagtaggtt taacatccat
     9241 aacctcatat ttttctttag cccactcttt taatccatat ctagtataat aaccttcaca
     9301 taaaaaactc aatggtatat ttattcctac agcacaaggc atacaatatt cacatcttct
     9361 acagaatttt ttacctaaag aatttcttat ttcttcaatt tccttattat ctttttcatc
     9421 tagcacaaga ttttcaagta cggccacatt ttgtctaacc tgttcaacac tctccatacc
     9481 tggtataact acatctatgt aatctttaga tagtatatat ttaatagcca atgttgcatt
     9541 atctaaagca cctccagcta aaggcttcat tactattatc ccaattcctt tttcatgagc
     9601 ttttttaaac acatcatctg cttgtccttc aactatattg taagggaatt gtatagtgtc
     9661 aaattttcca tcttctatag ctttttctat agtatttaaa ttgtgactag ttataccaat
     9721 atgttttatc ttaccttgct cttttgcctc taaaagggca ctataagcca ttttatcttt
     9781 aaaaagatta tcatattcct cttctttaac attatgaaat tgatataaat ctataaaatc
     9841 agttttaaaa ttatttaaac ttatttcaac atctctcttc attgaatcat aatctctaga
     9901 catactttta gtagctaaga aaaatttatc tctttttcct tcaatggcaa ttccgattgc
     9961 ttcctcactt atcgtatacc ctcttgcact gtcaataaag tttattcctt gcttttctaa
    10021 ctcatttata actaagttgg tatcatcttg agtaatcctt tgtattggaa tacctccaaa
    10081 accaactctc tttattttca tattagtatt gcctaaattt ctcatatctt tccccaccta
    10141 acttttaata attttttata taatataaat atgtcacctt taattataca acaaattatg
    10201 agaatctttg caatatattt acatactatt cataatatag ttatatttta tatcagtcta
    10261 ttcataatat catcatactt tatacccagt taattcgtat acaattttcg ttattcctat
    10321 ctattaattt aaattattac atttcatgat tgtatctcca ccctaattat gttaagagtg
    10381 gagtatttta catgtttaaa taaaatttta tttactagat aatatttctt ttatcatttt
    10441 aagctctctc ttatgacctt catcatcaaa aggagtttct aagaaaaatg gtaaatgttt
    10501 taaactagga tgttccataa aatcaattaa tgcttttaat cctatctttc cttcccctat
    10561 aggagcatgt ctgtcttttt tatctccaaa gggcatcata ctatcattta gatgaacagt
    10621 tttcaacctg tctataccta taaccttatc aaactcttcc aaaaccccat ctaaatcatt
    10681 cactatatca taaccagctg aaaaaatatg acatgtatca aggcacacac ctattttttc
    10741 tttgtgttcg attttatcta ttatactttt taattgctca aatttaaaac ctatttcagt
    10801 tccctttcct gacatggttt caagaagtat agttatattt tcatcgccct ttatagcatt
    10861 gttcaatcct tttactattc tatctatacc aaaatctaca ccaccaccta catgacttcc
    10921 aggatgaaag cacatgtatt caattcctaa tgaatccatc cttcttatat cctcatctat
    10981 cacccttgtt gcaaattcgt atacatcatc ctttgtgcca cccaagttca tagtatatgg
    11041 tgcatgtgca agcagtggtg caaaattatt tgcttttcta atttcttgaa atttaattat
    11101 atctttttca ttaaactctt tagcatttcc tcctcgtgga tttctactaa aaaattgaaa
    11161 tgtatttgca ccaatatata cagctgtctc agctgcatta gcaaatcctt ttgctattga
    11221 aagatgtgtt cctaatttaa tcatattaat ctccttttat ttgtactaca acttgtactc
    11281 aattttaatt ttgaactact ccaccttagc tactttcagc caacatctaa agatgaagat
    11341 tcctatagta cttttacact aaaaatttat aggctctaag ggatgttcca tccccactaa
    11401 tttcattcct cttttaatat atttctacca ttgatttaat ttatattaat ttttaatttt
    11461 aatatttaca ttttaattat acccattcta atcaatttca aatattataa tcttacaaac
    11521 tttgtataca ttatctaagc acttcttaga tagtgaatac atcttacaca ctatctatca
    11581 tttacaaaca caatagtata aagagacaaa aaaatagaga ttaaaaatca ttactttacc
    11641 ataccaaaaa ctattttttg attattaagt aaattttgat gttcaatctc taatcttata
    11701 tctttaatta agccataatt aattctttaa ctaggacatt cctcctcaag agtaggaact
    11761 ataaccatag ctatatcata cttagaacct tcaacattgt gttgtctttt atttaaaatt
    11821 tcatctatct ttgacttcat agtgtcacta agttcaacta attcatcatg agtaagagaa
    11881 atatcatgat aatcaactat attttcattt tctaaaacat cttcctctgc tgccttataa
    11941 aaaacttcac tcatattttc aaattttgat atgtacaatt cttctttttc ttccccattg
    12001 tctaaagaaa aattaagtat cctattccct ataaccacat tttttgcact tggataatag
    12061 tacttttcca caatccccga ctttattttt tcctcaacta attctaaaat accaactttg
    12121 tataacattt ttatatggta gtttattttt gcatgaggtt cttccaataa ttgagataat
    12181 tgttttgctg acaatggcga tttgtcaaat gcttttagaa tatctattct acgtggatgc
    12241 gcaatagcct ttatgcactc caaatctcgt aataccaata cctctttcat tgacccctcc
    12301 taaaaaattt atttaattca tatttcttta caatttaatt atatattaaa ttatatgttg
    12361 ttgtcaaaaa aatcctttct taatatttta aaaaatattt aatttgagtt tatttgacaa
    12421 ctcctctaaa actttaactc ctgcgacgct gttacctttt ttgtcaagcg caggtccata
    12481 aacaccaatc cccatgcgtc ccggcacaga agccattata ccacccccaa ctccagattt
    12541 tgcaggaatg ccaactttaa tagcaaattc cccagaagca tcatacattc cacaagtcat
    12601 cataaatgtc ttgacaattc tagaaaccat ttcactcatt aaatgctcgc cattttctat
    12661 atccactcca taatttgcaa gatttattcc aattctcgct aaatctacag aatctatctc
    12721 aattgagcat tgtttaaaat aaaggtctag aacatcttct acattacctc tgataaatcc
    12781 atcacttttc aataagtaag ccatagctct gtttctatct ccagtcattt tttcagactt
    12841 atagacatca tagtttattc ctatattatc attttttgct aactttctaa agaaactaag
    12901 cattctttct tctttttctt ctaaacaact cccatttata agggaagtag ttactatagc
    12961 ccctgcattt atcattggat tacagggttt ttttgtgtca ttaatttcaa gtttcattat
    13021 tgaattaaat gggtctccac ttggttccat tccaacgttt gaaaaaacgt cttcccaatc
    13081 attgtccata agtgccatag caagcacaat tggttttgaa atactttgta tagtaaactt
    13141 tgtgctacag tttccagcac tataaagatt attttcgcta tctatgatac aaattcctaa
    13201 atcatttctt ctagcgtttt ttaattctgg tatgtaacta gcaacttgtc cataattagt
    13261 atacttctta ttagaactta taatttcttt taataatgtc tcatctaacg tattcatatg
    13321 cacctcttat attatgttat atattctatt ttagcacaag tttgtactat aataaaacag
    13381 tgttaaaaaa aattatactt taaagttatt ttctacaaga atcaattcat ttttcaaaca
    13441 atttaaatag tttaaatggc ttaataattc agtaatctag taattcaata atttagtaat
    13501 ttaacaacct agtaatttag caattcagta atctaataat ccaataattt aaatttttat
    13561 aacaccaaaa ttttctaact caatatcttt tactctttta ctcttttact cttttactct
    13621 tttactcttt tactctttta ctcttttact cttttactct tttactcttt taaaaaatta
    13681 tcacacaaat taacaaaata ttaaacaaag aagtaaactt taaaataaaa agcttgcttc
    13741 atacaaaagt ataaaacaag cctttttata tatcaactca aactttaaaa tctgtatcaa
    13801 tttaattttc catttaatat acttcacata aaccaatcgc actatttact atgccattta
    13861 atcttcataa aataatctat aatacacata ttaatcaact attttacttc ctccaataaa
    13921 ttccctaaga attgaaatac ctggtatatc agaagtgtcg tccaattcaa caaaatactg
    13981 caaaaacttt agtaatctag tagcttcaat atgtgcagga ttatcttcct ttatatcttc
    14041 caacaaaggt ttcgcaaatc gttttaaaac tgccaattca tatacacaag cagagttaaa
    14101 tatagcatct gcctcttctt ggtatgggaa tatattcttc ttttctcctc ttctaactga
    14161 tgcccattgt aaaatagtat tatcagcact atatcctcta aaattatagt ctctaacaat
    14221 tcttcttatc attctcaaat cagcagtagg gattcgatta tggtcatcca aatttatttg
    14281 agtaagggca cttatgtata tcttaaattt atcttcatct ggtatagatg atgttaaaat
    14341 aggatttagc ccatgtatac cttctaatat aattggctga tttgaatcta tctttatttt
    14401 tttaccagta tactctctct tgccttcttt aaaattgaat cttatatcat caatttcttc
    14461 accagctaaa agtttcttta agtctaagtt aaacttctct aaatctattg cataaattga
    14521 ttcaaaatca taatttccat attcatctaa aggggtatgt tttctatcta taaaataatc
    14581 atctaaagaa atcgaaatag ggtttaaatt attcactcta agatgtattg ataatctgtg
    14641 agcaaaactt gtttttccag atgaagatgg agctgctatt aaaattactc tcttattgtt
    14701 atcctttatc atatctgcta tttgagataa cttcttttca tgcaatgctt caaatgttct
    14761 tattatatct ccatattcat tgttttctat tatcttatta agagatacta ccttgtcaat
    14821 tcccataagt cttgaccatt cttctgcttc ataatataca cttgatagct taggttgagg
    14881 tacaaatttc ataggaagag tcttatcttc ttcactagga cctaaaatta taacacctcc
    14941 attataaagc ttaatatcaa atgattttat ataaccagtt gatggcaaca tataaccata
    15001 aaaatggtct atatagtttc tacacttata tactttagca ctatcatact ctttgtattt
    15061 caaaagctct gccttttcat acatttcatt attttcaaag atagaaatag cttcatttct
    15121 tgtaacttca attttttcta taacataatc gttgtttact atctctttca tcttgttttt
    15181 tatattttca acatccactt ctttaagctt tctatctata tgaacttcac aatatagccc
    15241 atctgataac gaatgttcta ttgtaactct actatcccaa aagatttctc tacaagccat
    15301 tacaaatata aacgacatga ctctaaagta aactctctct ccatcttcat tagtagtatc
    15361 taaaaaattt atctcacaat ccttcttaac tctacaattt agctctttta gtttattgtc
    15421 tacaactgca agtgttatat aacccttatg ctcatcacaa aattctttgg ctatatctcc
    15481 caatctgata ccatgggaat tttcttctaa tgaatattcc ttatcttttc cttctatttt
    15541 taagtttatt tttttcactt caacatctcc ttccttttga tgaatataaa ttttaattaa
    15601 tgaggcatat caacaagata aagagaggta tttaaccctc tcctacaata ttatccaatt
    15661 tacttatagt atcttcaata tcttcgtaat ttatttctaa tactaaatat tctgcatcta
    15721 gtgttaagac ctctttaatc ccctcttcag ataaaattcc tcttcctata ccaacatgtg
    15781 tatcattgat accatcatta tcacttaagt gtatcagcct tattttatcc tttaagttct
    15841 ttacataatc atcctcatca attaaacagt gtccagtatc gtaacaaaaa caaatcttag
    15901 aatttttaat cctcttaaat atatattcaa aatcataaga tatatttcca atatttgaaa
    15961 aatccccacc ttttgaataa gtattctcta tacatacata tgaatttgta tttagtttgt
    16021 ctaaaaaatc cacactattt tctaaatatt tgtctctatt ccttctaact ctatttgtca
    16081 taacatatcc caaatgaagg ttaaaatacc ttatatcaaa tcctcttagt tcaaattcta
    16141 tcttctcaat aaaatttatc catgaatttc gtatatactc tatgttttcg caagtattta
    16201 actccatagg caagtgtatc cctatagata atcctaactt agaaattctc tctttatatt
    16261 tacatagatc actacattca gatatattgt caattccaat ctctaaatga gttatttgct
    16321 ttatactctc acaaatgttt aaagcctcct caatattaaa caataaggat gctataccaa
    16381 ctgccataca aatcacctac tcaaaaatac ctatatctgt aaaaggaaat actcttaaaa
    16441 taacttttcc tttaatattt tcttcatcta ctaatcccac ttctttatat ctactgtcta
    16501 aactaacttc tctattatct cccattgcaa atacttttcc cttaggaatc accatatcaa
    16561 tatcgccttc agtataatta tcatgtatat atgaaacttc atttaataac ttaccattta
    16621 tataaacctt agaatcctta atttttagat ggtcaccagg aacacctata acccttttta
    16681 caagctcttt tttccttcca ttctcttgta ataaatcagt cttaaatatc attatatctc
    16741 cacattttgg ttctgataac ttatatgtca tcctgtttgc taccaaataa tcatgtgatt
    16801 taagtgttgg gtacattgat tctccattta ctagtgttgg ttttataaaa cgagttataa
    16861 taaatgccaa aaaaagtgca gtaataatta tttttatcca ctctacaatc tcttctttaa
    16921 tagtttcatt cattcacaaa ttctccttta tagttatatt atctttatta ataatgtctc
    16981 ttaaacacta tcttttagat aagtctacta aataaggtgt tgtctttttt atatagacaa
    17041 ctattgtgta tggtctggtg atatcagtta atcagcgatt gctccaaatt ttatatgttt
    17101 agtcaatagt ccctatctta gaaaatggat acaatctgac tagaaccttt cctaaaatgg
    17161 catgctcgtc gaccaatcca acctcatcgt atctactatc taaacttttt tctctattat
    17221 ctcccattgc aaataatttt ccttctggaa ctacgatatc aacatctcca tcagtacgat
    17281 tattatgtat ataggaagtt tcatctaaca atttatcatt tacatatacc ttggagtctt
    17341 gtatttttac atggtcacca ggaaccccga taactctttt tactaaatct tttttctttc
    17401 cattttcctc tgttaagtcg gttttgaata ctattatatc tttgtatttt ggctctccta
    17461 ccttgtacgc aattctatta actatcaaat aatcacgttc aaccaatgta ggatacattg
    17521 attctccttt gactattgtt ggcactataa aacgagttat tgcaaatgcc aaaacaagag
    17581 ctatgacaat cacttttatc cattctacaa cttctttttt aactgcttca cccactaaaa
    17641 tcgtctcctc tgtattaaat attaagtcaa tctacagcaa aataatctac tataaaccta
    17701 caatataaat attatacttc ttttttctac tagtttaaaa tacttttcta agacctttag
    17761 gataatgatt cttaattaca ccagaagttt cttttcccca acctaaaggt atgccttcaa
    17821 ctgaaaccaa aacccatcct ctactatcat tagaatttac aacatcccct tttaaatatt
    17881 taagaattga ttcactctgt acactgaagt tttcaacatt ttttacatct tcaactttta
    17941 agtaatgaga tagtgcatga gaaggctcaa atctattctt ctttaaaacc cctaaatgca
    18001 aaccgtatct caatactttt agtttttttg tatctggata tattttagga agtaggtaca
    18061 aattttctct tcttaaataa aatttatttt ttttattact ataaaaatca acctttaaaa
    18121 atttcttttc aaactcccta taatccttta tttctttatc taaatttttt atttttaatt
    18181 ctttgacatt acattcttct tcttctaatt tttttatttt ggcaacaaaa tgcccttctc
    18241 cttttatctt atgaggccat aatctttcca tttcaataag ttctgcatgt ggatattcac
    18301 tgataaattc atttataaca tgctcatttt cttctcttga aaaagtacaa gttgagtaaa
    18361 ttaaaatacc atccttcttt aacattttat atccatctct tataatctct ttttggatgg
    18421 actgacactc tactaccttt gcatgactcc aatctgatat agcaacctcg tccttcctaa
    18481 acataccttg cccagaacaa ggtgcatcta taataacctt atcaaaatac ccattaaacg
    18541 tctttcttaa gctattagaa tcagtgtttg ttataataca atttctcgct ccaaatcgct
    18601 ctagattttc ccctagagcc ttaattctac taacattaat ttcattagaa accaataaac
    18661 ctgtatcatt tagcttagat agtatatatg tagattttcc accaggagca gcacacatat
    18721 cgagaacttt ttcaccttct ttaatatctg cctttggtat tacactcatt gcagaaggct
    18781 cttgcaaata gtatgctcca gcctcatgca gtggatttct accaggtcta tcaattttat
    18841 catcataata aaaaccttct tctgcccatg atatttgatt caaatcaaac agacccaaat
    18901 caaataattt tttcttgtca atttttagag tatttattct aagcccagta gtcttacttt
    18961 cttcataact ttttataaaa tcatcatatt catcttttag tatttcttca acatcttcta
    19021 aaaattcttt tggtaacttt gtcaaatcta taatccccct tcaatctgct ttacttgtgt
    19081 gtcatttatt atactttaat tatttatttc tttctcttaa attttatttc ttcttctttt
    19141 tcctaagatt accgaaaaac acttttttag agttattcat atatttctca agtttatcaa
    19201 gatttatctt ccacaaaagt attacataaa ctataagtaa tataatagcc catctatatt
    19261 ctatcatcaa tatgaaatca aaaactccat gtaataaaat tggaattaac actgccataa
    19321 acaaatactc acgtctttta tttttatttc cctcaaattt atacttagaa atatagtaac
    19381 ccatagtaat tgcaaacatt acatgagctg gtatagagat gactgctcta ttaataccaa
    19441 cttgcagtgc tagatttcta ctttcagaaa aaatataaac catattttca attgttgcaa
    19501 atcctaaagc taaaaataca gagtaaataa taccatctaa cttttcagta aaatgttttt
    19561 ctttaattaa ggcaggaatc agtatcagag cttttacccc ctcttctaca agtcctgcaa
    19621 caacaaatga tacatatatt agttctgaat aaccttcaaa tacattaaac ttcatcagta
    19681 aattttctaa aagtataatt ataacactta gaaaagcacc gattaaaaaa aatttaatta
    19741 gatgtattag aggttctcta caatatctat ctttagacct tatccaaaac attcctatca
    19801 atataggaac tattgctaat aaaaataaat ctagcttcat agattatttt cctttcaaaa
    19861 attttgattt atttatgact tatatcatct acttattttt aacttattta tgttttaaat
    19921 acacactaaa atatacatta aattatttta aattatttaa atacaaatat actcaaaaaa
    19981 atttaaattt atatctatat tatttaacaa atttcaagct atattcatat cttgaaatat
    20041 aagggaacta aattcattta aagaaagggt gatttgatgc aagatggttt cttaacagta
    20101 agcataattg atgctactaa caatagacct attcaaaatg cagtagtaaa catatattca
    20161 atgtctaatg gtagccaaag ctcatcaact ttataccaaa acctaagaag taatgaatct
    20221 ggtcaagtga ctgggttagt attaccagca ccagatgtag attactctct acaaccatct
    20281 gatgttagac cttacagcca gtatatagtg gaagccatag cagatggata tgagacagtt
    20341 gtcatagagg gaacacagtt attagctaca attgaagcaa gacaaggagt tcccatgtct
    20401 cctagaacaa gaagtaaacg ttctttctca agacaaagtg agttgatttt tgacatagga
    20461 gaacatactt tatatggtac ttatcctcct aagattccag aaagtaactt aaaaccatta
    20521 ccacctccta ctggtttcgt tgtattagat aaccctgtag tgcctgaatt tatagtagtt
    20581 cacgatggtt taccagaaga ttcatcagct ccaaactatt ggattccatt taaagagtac
    20641 attaaaaaca tagcatcatc tgaaatatat tcaacttggc ctgagcagac aatctatgca
    20701 aatgtaatag ctataatatc atttacttta aatagagtct ttactgaatg gtatagaaat
    20761 aaaggataca actttacaat aacttcaaca acaacatatg accataaatt tataaataat
    20821 agaaacttat ttgaaccaat taacgtagtc gtagatgcta tttttaatac ctttataaaa
    20881 agacctccta catcaagaca gccactatta gcacaatatt gtgatggaca aaaatcccaa
    20941 tgtcctgacc aaatgactca atggggcagt aaagatttag gtgaccaagg atatgactat
    21001 gagagtatac taagattttt ctatggagat gagatagtgt ttgaaagagc acctatagta
    21061 agtggtgtac cagtatcatt ccctggtact acactacaag ttggttcttc tgggcagtat
    21121 gttagaacta tacaaaatca gttaaatgcc atatctaatt cttatccagc tgtcccaaaa
    21181 gttatagaag atggtatcta tggaacagat acagaaaatg ctgttaggat attccaaggc
    21241 atctttggtt tacctcaaag cggagtagta gattttaaaa catggtatga aatatccagg
    21301 gtttatgtag ctacaactag aatagcttct ttaaatcctt taatttaaag cttgatttag
    21361 aatataaact caaattatta aataaaatta ttaacttaaa ataaaaatgg ctgttatgaa
    21421 ctaacatata ccataagtat ttttacttat aagtattgta gtcttaacag ccatttttta
    21481 gttataactt atttttttag aaccttaaaa ctttaaatgg gggattttaa gcttcttaaa
    21541 aacagtgctt agcaacttta atttctttaa aaatcttatc tttattttta aatttaataa
    21601 aatgctattt taatgaaaag cttacttttt acttagagcc tcaattctta tttaaaatgc
    21661 tacttctcat ttagaatatt actccttatt atttaaaaca ttatttctca cttagaatat
    21721 tacttcccat ctaaattatt atttattcat tataaatata aacactatta atttaaaaag
    21781 ttattcctaa ttttaataat accatttcct tatcaataga cctaaaccgc aactttagac
    21841 ttattagcta aagccaatat tagacctaaa gctatagatg caaatgcaga agcaattact
    21901 ctatactcag cagggaataa gaatacaatt gtatgacatg gtatccagaa aaatggtata
    21961 gtttttaaaa cactaaaacc aagataagca ttccagtcca caatatttac cacatcttta
    22021 agttttacct taataccctt tccaacttca tattttttat ctataaaaca atccataacc
    22081 ttatggaata aaaatacagt tggtgacatt agtatattca tagttgcgct cttaaataga
    22141 gcatttgcaa aagctattcc ctcaaatgga agcataccat ccacttgtgc ttgacctaca
    22201 cctgatgagt aaattgacat tccatatgtg gtaactatac ctattattcc ccaaactatt
    22261 gctctataaa atactcctac tggtattttc cagtccttat acaaaattct agcaccaagt
    22321 aaatctccca ttgtagctaa tacagcaaac ttaaaaaaac ctccaatata tggatgtgca
    22381 cctgttgctt ccataaatac ttctctacta cttggtattg ctaagacagc aataatgcaa
    22441 ataagaattc cactccatat aaaatcgcct tttttcatat tataaatact atttaatata
    22501 taaatagttc tcctttctat taaagattta tttaatttac aatctatcta caattattta
    22561 ttaatcactg attattagat attcattttc catgtttaaa tttattctag ccctttatct
    22621 atttattttc ttactttttt tatccaccac tatctatata tttattttac gattactctt
    22681 tcaccctaac cctttaacta tctatttgtt ttttactact cttatctacc agtatctata
    22741 tatctacttt acaagtactc tttcacccta actctttaac tatctatttg ttttttacta
    22801 ttcttatcta tcagtatcta tatatctact ttacaagtac tctttcaccc taactcttta
    22861 actatctatt tgttttttta ctattcttat ctaccagtat ctatatctac tttacaagta
    22921 ctctttcacc ctaactcttt aactatctat ttgtttttta ctattcttat ctaccagtat
    22981 ctatatatct actttacaag tactctttta acccaacctc ctatacttta tatagtaata
    23041 tgtttttaac ttttttcatt attctcaata tgttttataa ctacaaatac tctccctcct
    23101 taaaaataag aataaaatta accaacaaat ttataatcat attattactt tatgtattaa
    23161 gcaattacta tgccaataaa ttttaatttt tttaaacaac tcttaaaaat gctaaaatgc
    23221 taattttctt taacttttaa tgaatctaat agataacatt taatttttgt tatatttttc
    23281 agaatgtttc aattattatt tttaagataa aaaaataatg ttaacatttc ttaacataca
    23341 ttaaaaaatg ttaacattat aaattgggtt taatactttt actttgactc gatttacttt
    23401 tattctactt ctttacttta ttttaactta gactttattt ttttatcact tatttgagtc
    23461 ttatttattt tattctcatt ctatatgttc aattaaattt gtctaagttc tttgatattt
    23521 ttattacata attttaacaa gcttaagtgt tatttgggta gtgcaattga taattattta
    23581 aataatcatc aattgcatgt ttgtatcatc atagtagctt catgtattta atcatgttta
    23641 cttaggattt tgaaatatct tagagattat atataacatt agtcaattgc tgcataattg
    23701 taagcaattg aaatttgaga cccatcttca ttttttatag tgataggctt cataattttt
    23761 aatccttcag tttttatctt ttctaaatct ttttccattt tcttaattgt ttcctcaaga
    23821 tctttttgac ttacatcttt aaccgcatta gggtctttag cataatcttt taattcttga
    23881 atatgtttag catattcttc ataagtataa tgctcaacac catatttttc taattcagta
    23941 gggtcagtta ttcctgattt tattagagat tcaagtttag gtaaagcaat attagatgaa
    24001 tcatttccat ttgcaaatac tgctccagtt cctcctagta ccattgcaga taccatcatt
    24061 gcacttataa gggatttttt tattttcata accaatcttc ctttcttata tatttatttg
    24121 gatagtgtag tttaaaacga ctattgcaat agttatcaac cacacattta gactaccaca
    24181 atagtcatat ttatgtcaag tatttcacta aaatttttta ataaaaaata ctacctcaaa
    24241 acaaacttaa ttattttaag atagtatttt aattctaatt gctttgtgct attatgattt
    24301 gcacttactt tatagaagtt ctgtattgta tattattaac tgctaacaaa tttccttttc
    24361 ttgatataac taaaacaccc tcattataat tatttttctg aattgaatat tctgctgaag
    24421 gagtataaag tacatcttca taatcattag atttgcttga tttctctaca gatacttctg
    24481 aataattctc agtattcctt actttattca tagatatatc ttcataactt ttagattcac
    24541 ttgatttatt catagatact tttgacatac taacagagat atttgaatct acttttggag
    24601 tatataactc agttgagtca ctacttattg aaagtacact tttctcattt tttgttaaac
    24661 caaaagattc aacctcatta atctctttat tttctgttgc aaaaacaaga cctatcccac
    24721 aaactaatac agttgaaact aaaaaagtaa cataagttga ttttttaaat ttcataatat
    24781 taactattct cttttctatt tttgtctttc caaacccact acatattgtc attgaaaatg
    24841 gattattctc ctctgctaaa cttattagtg tagttgcata atcagcccta tattcctcac
    24901 caagtatact cataaccttt tcatcacaac taaattctat gtctttattt agtaaaaaaa
    24961 acatcaccca aactaaggga ttaaaccaat gaacaacaag agctacaagc ataaacagct
    25021 tcaacagatt atcaaaacta ttaatatgaa ccatttcatg agttaaaaca aagtctaaag
    25081 tttgattatt agcataattc atttgcttcg gcaaaataat tcgtggtttt aaaataccag
    25141 atgtaagtgg cgttctagta aattcagata tacaaacaat aaatcttcta aaacggctat
    25201 tcttacacat ccatttttta atgaactcgt gattttttat atgaattgaa gttttaaaaa
    25261 gattaattat tttaatatat ctaaaacata aaagtatgct aaatataata gtaactataa
    25321 aagacaaaat gcccaacatt tccaacatca taatattttc aatactagac attatttcaa
    25381 atttgtcaga attgttttta cctgtagagt caccagcttt cttaagagta taattttccg
    25441 ttgatgcatt ccccaattct acatcaaaag tcgattcaat tatactataa atactaaaac
    25501 cagaatttaa acttactggt attagaagtt taaataaaac aatcaaccac aataatacaa
    25561 acaccttttt aggtaatttt ttaaataaac atgctcttat aaaaataact attaaaagta
    25621 atactccaga agtaaaactc atttctaaca atttaatgaa cataaatctt acctcacttt
    25681 aatttttcaa caatctgttt aagttttgta atctcatcac ttgaaagatt ttctttgtta
    25741 ataaaagctg aaagaaattt ttctgaagac cctccaaaca ttttattaat taaagtttct
    25801 gtttcctgtt tttgtacttc ttccttgctt attaaagctt tacaaacaaa attcggctca
    25861 attctctcta ttgcaccttt tgacaccaat ttttttataa ccgtatacgt agtgtttcta
    25921 ttccatcctg tttcttcttt taaaattttt actaactctc cagccttgct ttctcctctc
    25981 tcccatagaa cttccattac tttaagttct gaatcaaata attttatctc catataaaat
    26041 cgctcctcaa atatagttat cacaatagtc attactataa taaaaaacta tcatagtagt
    26101 ctatgctatg tcaatccttt attttttaat aataaaaact gccttttaaa aaatttctta
    26161 taaaagacag ttttatcaat gttatacttt gatgtttaat caaagccata ttttatttga
    26221 atgtataact atctatctta atacatagta taagattttt ctttatctaa tagtatatcc
    26281 tctacgtctg ggttttcttt tactaattgt ctataaaagt tacaattagt aacacctaca
    26341 tatggaatta accatagtag acctattcca agagtagcta ttgaaagtat ataccatcct
    26401 ataaaactaa agtttagtac aaataattta agtacatttc ctttcatcat atctaaacta
    26461 gcactcattg atttaaatac gcccagatta tccttgtttt cacaaattag gaaagtagct
    26521 tgagaaacat ataatagcaa tatataaact ggtaacataa gaacgagtat tataagaact
    26581 agagttattc cagtagaaat aatagttcct attccaacat tgtcacttga taaatattca
    26641 attgcaccac tagtaagtaa aactccaaat gataaaaatg ctcctataat tgtgattata
    26701 aaagaataaa tataaacaat aattgattca aataaataaa aaccaaaact tcttaaataa
    26761 attctcccat ttacaaaaat atctcccatc ttgacttttt catctttagt aattttcaag
    26821 aacatacatg tgaatcctgc tgaaacacag aaagctatta cagccactac aatagtagtc
    26881 aatggttcaa aaggtaatcc tacaattgat attaacacta tcaatgcaat atatactgcc
    26941 atagaaattg cacatatacc ccagtttcca gacaactgag ctttagatac tctttttaat
    27001 tcttgccttg ataccataaa aaacacccct ttcattttat aaaaaaactt ttaaaaatat
    27061 aaataatctt ttaacatata atattaatat atcatatttt cgactatata acatacaatt
    27121 attcaccatg ttttatcaag atatgtcata attgtgttac tagttttata tagtcaatat
    27181 taccaagtac atcaaataaa tttgactaat tatacgacaa ataataaaat acattatact
    27241 aattttactt tatttaataa acaaattatc caataaaata cattacttaa taaagtatat
    27301 taattagtaa gataaattat ttattattag taaggtaaat tatttactat ttgtcaagat
    27361 aaattattta taaaataaat cacttataaa atataattta tactttgaga ataaaataaa
    27421 ctatcttcca aacattttat tatatgctta aaagatagtt ttgtgtcttt aaaataaatt
    27481 aaattgtata tattccttca cataactttt gtatattact aggtggttgc catttaccat
    27541 cttttttagt atatgtaatc atagttgtaa cttccttagt cggcttctta ttgtaaaggt
    27601 ctataatcat ttttgccata tcatcttgaa cttctttttc ttttttatcg taattctttt
    27661 catcagttac ataagatttt actaaattgt tcgcttcact cattacttta ctagtatcta
    27721 aagctttgct tacaactttc aaagttatct tatccttact agaagattcc actgttacag
    27781 tcttttcaac accttgaatt aacttaacaa ttgtttcgta tatcttttca gcattttctt
    27841 taccataaag aggtgtcaac tgagcaatca ttgaaacctt atccttgctg ttataagttt
    27901 gaatctgttt atattcagct tctgttaatg catcagcaat tcctttttca tcatacttat
    27961 acatttctaa tgcagctaaa ttagcttcaa aatttgactt tactttttct tctgcattag
    28021 aacaccctat agttagaact aaaacgagag ccataataga agataatatt aactttttta
    28081 ccattttcat acaaatatcc tccctcaatt aaaataataa aaaatttatt tatcaacatt
    28141 ataacataaa tttatctaac tatagaatta ttttgaatat tttaccattt ccagtccatt
    28201 ccgataccgt tttcttttgc tttgtcgtat attctttttg ctgttacgac gtcttgtaca
    28261 cctattccga cagttttaaa cacaattatc tcatcatcat cttctctgcc aggaatagtt
    28321 ccatttataa catttcctaa atcaccacta aaatcatctt tacttatctt cccttctttt
    28381 aatggaatca atatatctcc tgactcagat aaaactgcat ctgttgattc aaaaaatatc
    28441 ttagatgctc tagttaaaca aattggacac aactcctgca tgtctggcat atatgagcct
    28501 actgcactta ttaaagctcc tttttttact aagtttccat taaatactgg ttgttttgat
    28561 ggagtagcta aaactattac atctgcatta tctatggctt catcagatga ttcaactgca
    28621 actattttag tattatattt acttaatttt aaattcattt cttctacaaa tttttctcta
    28681 ttttccttgt ttctactaaa aactcttacc tcatccaaat ttctagcttc tatcatagct
    28741 tcaagttgag gctcaccttg tcctccaaca cctatcaaag ctccaatctt agaatctttt
    28801 ttagccaaaa catctatggc tgctccagat gctgctccgg tacgaatttg agttacataa
    28861 gtaccatcca atactgcact tacttctcca gtttcaccat ctaatagtag tactgttgct
    28921 ggaattactg gcttgccttt ttgagcattt ttaggaaata cagatacaat ttttattccc
    28981 ccacacccta attcttctac ataccctggc atgaataaca tactagcatc ttgacttgga
    29041 actggtatat tggttctcaa gggatttaca ctctttcctt cacaataaat tctaaaagct
    29101 tccttatcag cttcaattgc atctctcatt gtaaatactt tttttatgtc gtcttttttt
    29161 aaaagtagca tttttatacc ccccaatttt aataagtctc tatgttaaat attatagcat
    29221 aacatttaat ttaatcttct atttcaaatc aaataaatct acatattctg gttttagcat
    29281 agagcttatc agttttttat ttattgaaaa ttctggaatc cctgctgcat atggagttat
    29341 atcatataaa tcaaaatata taactagatt atcatcttgc aaataaaagt tttgattctc
    29401 ttttatacct ttaaaattat atattccgat attttcttca tccttttttt caagttcagc
    29461 tatttgtctt ttaatttctt catctataac ttctttatat ttagtattat ccttaaataa
    29521 gtccattaat tctaaaaatt ttccagttct catatccaca ttatatgctg tatcttgata
    29581 aaatccatgt gctccaccac tataagtata atatctcact tttatactaa gagcagaatc
    29641 agtattcttt ttaagttcaa aatctacatt tgcaacaaac ttatttttct catcaggatt
    29701 atccttaaga tactgctttg cttctttata tgatttatta taaaattcaa atatgtcatt
    29761 ttttatctta tcatttgtag acctttcaac aatcttattt gaatttgtta ttacaggcat
    29821 gtttatagta ctttctaaat actcatcatt tttcactatt gttttacttc ctattgtact
    29881 tactgataaa gtttgtttac tatttgtatt accctttggt aatgactgat tactcataac
    29941 gctcactgct tccttattat ttaaattaat tgaagcattt ttcaaattat tatatttata
    30001 gtcatgttta attgccaaaa cagccattat agtcaaggtt aaaacaaata catatcttaa
    30061 aactttagct tttgtatcca ctttaaaaaa tttcatatta tcattttcct cctaaatata
    30121 aatctctctt attatatttg gagtttctag ggttttttat ccatataatt taataaaaga
    30181 ttaattttta tttataaaaa attaatcttt ttgttttaaa atattaatat gtcttatcaa
    30241 acagtttgaa atttcaccaa gaggtaattg taacataaca gaacccctat caaaagctac
    30301 cattggcatt ccatatacta tacaagaatt ttcatcctgt ccaattgtaa atgaaccatt
    30361 ttctttcatt tttaaaagtc catttgctcc atcataaccc atacctgtaa gtattattcc
    30421 tatcgaattt ttacctgcta cttctgctac tgaatcaaac aatacatcta ctgatggaca
    30481 gtgaccactt attctttctc ctttttcaca agttacataa tatccttgtt tatccgcaca
    30541 caatttcatc tggcaacccc caggtgcaat taatacattt ccttgttcga ctctatcatt
    30601 attcttagct tctcttacat tcataataca ctgcttgtca agccgttgtg catacatata
    30661 agtaaatata gctggcatat gttgaactac aacaatccct ggtgttgatt ttggtaagtc
    30721 ttttataatt tcaagtattg cttctgtacc acctacagat gcgcctatag caataaccat
    30781 attattaaaa cgtcccacat taccgcctcc acaaaatcat atatcaaaac tagcatttta
    30841 tcttttatat atagcaggtt ttacatattt atatttagta ttacttctgt taattacctc
    30901 tgcatgtcct acaaacaaaa aactatcttt tttggtagca ttataaaatt tatttataag
    30961 ttcttctctt gtttttaaat caaaataaat cataacattt ctacaaaaaa tcaaatcaaa
    31021 atgttgatat gaaaaatcat tcattaaatt aaatggcttg aaaattacac tttttctaat
    31081 cttatcacaa attttaaatg taccatcctt attgtctata aaatacttct tcttccataa
    31141 ctcaggaaca ttgttaacat ttgattctat gtatatacct cttttagctt tttcaagtga
    31201 gttagttgaa atatctgtgg ctatgatttt aatgttccac aactctttat tatatccaaa
    31261 ataatcatcc aaagtcatag ctattgaata cgcttcttct ccactggaac agcctgcact
    31321 ccatatattt atgtttctta ttttattatt ttcttcccag aaaggaaata tactattctg
    31381 tataaactca aagtgttgag gttctctcat aaaaaatgta tgattggtgc tcaatctatt
    31441 tattaggttt atagcttcat ttcctgtctt atctttaaat aatagattca tatattgact
    31501 aaaagaacta agttttctct ctatcattgt attgtataag cgaccttcaa ttaacgctct
    31561 ttttttgctt aaatcaatac catattcttt ttttacatgg tttacaagaa ctataaattc
    31621 ttcatctgtg agttttatca tgcaaaaact tcctcctgct aatttatcaa aactaactat
    31681 atgctattaa tcaaaaactt tcgaatatct aaaattaata tagaattatc ttcaactttc
    31741 gcaatttctt ttatatcttt attaatatta atattgttag aattagttgt agctagcaaa
    31801 tttagatttt ctataggaat aacatcaata actctatcta caataattcc aacttgatac
    31861 tcatcaacct ttgtaattat tatacaagtt ctctcattat aatcagcttc aggaagatta
    31921 tactttatat gcatattaat aactggtatt attcttcctc gcaaattaat aactccactt
    31981 atatatgttg gaagacatgg tacatacgtt attgattgaa atcttatggt ctcaatcaca
    32041 ttttctaatt ctattccata aataacatca ttgacataaa atgttaatac ttgtttaata
    32101 atttcatctt tagccatact ttaaatcccc taatatattt ctataatgct atctgcatct
    32161 ataattaagc ttatacttcc atccccaagt attgtgcaac ctgataaacc cttatttttt
    32221 atattgaatc ggttaaagta aactggaaat ggtttcacaa caacttgttg attacctatt
    32281 atttcatcaa caaaaatgca tactgcttta ttctcatttt caataattat catattacca
    32341 tgcatcagat tggttacttt tgtttgaata ttatatattt tatgtaatct tataatagga
    32401 atacatgctc catatattgt aattaactct gttttatttt cttctgtaat tatttgattt
    32461 aagtctgtaa gtttaaatgt tctccttata gatgatattg gtaaagtaaa tagtgaatct
    32521 ccaactttaa acttcatacc ctctactata gaaagagtta gtggtatttt tatagtaaaa
    32581 gttgtccctt catctggttt actttttact tcaattgaac ctccaacctt ttcaatactt
    32641 ttacgaacaa tgtccatacc cactcctcta ccagaaaatt cagttataga ttcttttgta
    32701 gaaaaacctg gagtcataat caaagaattg acctcctcat cagtatactc attggtttga
    32761 tgtttaagga gaccttgttc cttagctttt gctaaaatct tgtctttcat aatgcctcta
    32821 ccatcatctg aaatacttat cacagcttct ccacctaaat tttcagcaga taaaactatc
    32881 tttcccactt cttttttgcc tttagctata cgttcttcga taggctctat cgcatggtcc
    32941 atagcatttc ttataaggtg cataaaaggt tctgttaaat tatcaattac actcttatct
    33001 acctctgtct ctgctcctat agttattaac tctacatttt tatctaattt tttattcatg
    33061 tctcgtacaa ttctatgcat tttttgaaat acaccagcaa tttgaatcat acgcatagac
    33121 attactatat cttgcaattc atctgtaagc ttgtgtaatt gtcttgttga cttattgaaa
    33181 ttatctatat caacacctgt agaatttaca ctatttacaa ccattgattc cataattaca
    33241 atttctccaa ctatattttg aagtaagtcc aatttttcta aatttacact cataatactc
    33301 tgcttactta ttggtaaatg ttcattttct ccacttagac catctttttc tatatcagtt
    33361 ttttcattta aaacatcttc ttgtaactca tcttctgtat agttattttt ataactttta
    33421 cttactttgt tactatcttt taatttgttt tctacttcat tattgtttga tgtacttttc
    33481 atttctattt cttttttact aatatttata tattctttta catagagatt ctcttctatg
    33541 attttataaa ctattgaatt atcctcttta gcaacaaatt gtatataaaa cccataattt
    33601 ttaatatatt ctgtagactc tgcatttgtt tctacatctt ttggataaaa atctagaaat
    33661 tcacagtaat ctctaagttc aaatacaagc atgaaagctc tcacattttc catcatgcaa
    33721 ccttgttcaa agattatttt tactacatca gaaccttctc tgtatgcaaa atttaagtct
    33781 attacttcta tttcatctgt actttctaaa cttgcattat cctttgattt catagaactt
    33841 gataattcca aagtactcac ataatcttca attccttcga taaaattaga gtaatcagaa
    33901 gatatacaac ctcttgattg taactcatct atatctcttc ttataaaatc taaagattga
    33961 aaaactaaat caaataatag gtcattgtct aaaacttcta ttttaccttc acgtatagca
    34021 taaaacaagt cttctacact atgtgctaaa gcagatatat tgtctaaccc catcatagat
    34081 gctgaacctt ttatcgtatg cattattcta aaagtttcat taatattgtt atgagtaaat
    34141 actttctctt tttctatttg aatcataatt tcatctaatt gttcgagtaa tagacttgtc
    34201 tcaaatataa acatatctaa catttgtctc atactcggtt caatataatt cacatttatc
    34261 acctacgacc tacaaataat tttctattat atatgcatct cataatttaa atccttgatg
    34321 attctattat ttcactatat atgtacctca taatttaaat atacaataac tctcttattt
    34381 cgttatatat gcacctcata atttaaaccc atgatgattc tcttacttcc ctttccttta
    34441 gatgaaattt ttctactaat tcttttaaaa tttgcgcttg agcagacatc tcttctgagg
    34501 ctgctgcact ttcctctgct gttgctgagt tcatttggac tactatggaa atttgctcta
    34561 ttccagataa aatctgtgta attgctactt cttgactatg tacagctgaa gaaataccat
    34621 taatataatc agtagttttt tctacaccat ttactaccaa ctccaatgca tttgcagtct
    34681 ctttagcaat tttgacacca ttttctactg ttttaatagc ttcttctatg agaatagctg
    34741 tattttgagc tgcttttgca ctttttccag ccaaagacct aacttcatct gctacaactg
    34801 caaatcccct accatattga cctgctcttg ctgcttcaac agctgcattt aatgcaagaa
    34861 tattagtttg aaatgctatc tcatctattg ttttaattat ttttgatatt tcactcgatt
    34921 tttcacttat ttcacccatt gatgtcatca tatcatccat acatctactt ccaaaatcaa
    34981 cttgtgatgc agattggtca gatacctcac atgcaagact agcactatct gcacacttct
    35041 taattccatc tgatatttca ttaattgtgg aagccaattc ttctactgaa ctagcttgtt
    35101 cagtagcacc ctgtgaaaga gcttgtgcac ctgctgcaac ctgttctgat gcacttgcaa
    35161 cttgctctgc tgataaattt atttcagaaa aatcaccatt aaaagagttt attatacttt
    35221 ctaaagatat ttttattgat ttaaaatcac ctataaattc ttggtctatt tctactctta
    35281 aatctccttt tgcaatacta gttaatgtac tgtctataag gtctatataa tttaaaagca
    35341 tactttgcat ctttttgaca gaactcacta acagccctat ttcagattta ctttcttcaa
    35401 cgtctatact tgttcttaaa tccccagatg caattcttga aaagtgtttt tctactttat
    35461 taataggaat aactattttt aattttatta ctgtatattc tattattgtc agtattatta
    35521 agagagaaag tataaatatt gttcttaata ttagactttg taattctttt tttacttcta
    35581 caattttggc atttgaacgg gcaactatat cctcttgaaa ttcatttatt aaagaatcca
    35641 ttttctcttg ggagtttata taatcactac taaaaattat attttgagct ttactcttat
    35701 cattactttc gactgccttt attgcacttt gttctgttgg taccaaagaa tctgatattt
    35761 cttttgcttc taagatttta tttgactcgc tctttgtaag accaattttc tctaatttgt
    35821 tcaaagctga ttctcttgtt tttccgtaca attctttttc ataaatatct ttattctttt
    35881 tttctcctgt aaatacatat cttcttaata catcacttat ctctctagtt gtatctttta
    35941 tatactgact ttgagttctc aaattattca tatcattaat acttttttct actttttcaa
    36001 atgctttata agatgaaata gaagaaaaaa tccctgctag aacagccaat actataataa
    36061 ccagcaatac aattgctaat ttagaaagct ttacttctct tttcatatct gtactccttt
    36121 acaaagtaag tttatatctt ttttaatcct ttcattgtac tcactacgct acaatctttt
    36181 cctaagtttt taccctcata cattacttta tctgctaagg atatattttc ttctaatgat
    36241 atatttgagt ttacttctac tactcctaat gtaatagtgc actttatttt attttcttta
    36301 tagttgaaat caaactcctt tatttcttta cggattcttt ctgaaagtat cttagcgtct
    36361 tctattggag tatttgtgag cattatcaaa aactcttctc caccccatct tgatacagtg
    36421 tcaatttgtc tacaattctt ttttattata cttgatatta ttgttaacac gaagtccccc
    36481 gcttcatgtc cataagtatc attgataacc ttaaagtcat caatatcacc aaggataagg
    36541 gatattgatg tttcactata tttattaatt cttctttgct ccataagttg attaattata
    36601 tgtcgcctat tgtaaagacc tgtaagataa tctcttacaa cgagtctatt caatttttca
    36661 agagaagatt ccagttcatt atttatcttt tttaatttat cttgagattt ctttacttca
    36721 agatgagcta taacacgagc ttttaattct gtcatactaa aaggtttcac catataatca
    36781 attgctccta caccaaatcc ttttactatg tctgtatctg cattttttga agttataaaa
    36841 attataggta tatctgctgt gcgagcatta gattttactt ccttacaaaa atcaaaacca
    36901 gagttatctg gtaaaattat atcaagcaaa ataatatctg gtataaattc ttcaataaac
    36961 ttttttgcct ctattgcatt aaatgctttt ttaaccttaa aattatcttt tgtaagtgct
    37021 ttatctatta agtcacacat cagaacacta tcatcaacga ctaaaattgt tccctgttgc
    37081 ttatttttca tatacaaacc tctcttaaac ataatatatt taaattttaa ttatttaaaa
    37141 tttttatact taataattat accactatat tcttaaatgt tctcataaca atctttttat
    37201 aataacattc caactacatc cctatattac atgatagtgc aatcaaaccc attgattaat
    37261 tcatctatta aaatttcatc tttatctgtt aaaagtttct ctaaatctag taaagtaatt
    37321 actttaccat ctaattctcc aataccgctt acaaaataat ctgaatattc tatagtaact
    37381 cttggtggag gagatatttc acttttttct aggcttatta tatcatcaac tctatcaacc
    37441 acaaatccaa ctactaagtc ttttatttca gttactacta tatacataca atttgtaatc
    37501 attaattcat cttttttaag tctcaaacgc atatctatta ttggaataat tttccccctt
    37561 agatttatta tacctttaga atatgtaggt agttctggaa taaatataat ttcttgattt
    37621 ccagtaattt ctattacttt ttcaagttca accccaaaat cttgttcatc tactttaaac
    37681 tttaaatact taattccttc atcaattaat ccataatcta aatatgggtc atctggaaat
    37741 ctcatttaat acctccctac taaaatatac tttctataaa atctatatta tagtttcttt
    37801 ttccccttat ttattgaatc tacaattaat tcacctgttt cagtataaaa acgtattgtt
    37861 cttccataat tcatacctgt gtcctcagct aatattggaa tatttaatcc taaaagagtt
    37921 ttttttactg cctcaacatt cctgtgtcct atacttgcaa ttgctgaatt gctatttcct
    37981 aaaaacatct gagcccctcc agcaattttt gcttttatat atattctatt tgcacctata
    38041 ttctccatag atttaatgag ctcttttatt cctgtgtcag caaatttata cttattttca
    38101 atgttgatag catctttact atatggcaac ataacatgca acattccacc aattccagct
    38161 actttatcta tcaaacatac tcctacacaa gaaccaagtg cataagtaac taaaacattt
    38221 ggtctatagg ctatcttcat atctgcaatg ttcactacta tctccctatt catatctcta
    38281 atcccaactt cactagtatt tctctaagtg agctcatttc tggaatcatc aaaatgtgac
    38341 tagtaaagta attatcactc attttaaact tattttctac aaataaaact ttgtcaccaa
    38401 catctgaaaa tcttatcata ggcacattta gaacagctcc aaccatatca atacatatat
    38461 ctggaattga aacacttata gtcatgttta acatagatgc aatagcattt acatatgaac
    38521 ttgccataat atttcctatt tctttaattg ctgaaatttc aatttcctca atatcatcta
    38581 aaggaacttc ttctttatta aaaagagaac ttagcataag ttgagttatt gattcatcca
    38641 acaaaaacat aaacattcca ttaatatcgc ctttcatatc gagtaaaata catactactt
    38701 tgttttctgg accaccaagc aaatttgtcg cttcgttata ttcaagtatc ttgaccatag
    38761 gtattaatac ttctacatta ctatttatca tggatgcaag tgaagtaatt gcattcccag
    38821 agcctatatt accaatttct ctaagagcat ctatatgagc atcatcaagt tctaaataat
    38881 ttataatata aacccctccc tctattatta aatttatttg atttttattg tatcagtata
    38941 tatttacact tttattttaa agcattattt acaactttaa ctaatgtttc tgttttgaag
    39001 ggtttcacta taaaatctaa tgctccaagt tttatggcat ctacaatcat attctcttgt
    39061 cctattgcag agcacattac aaccttagca cttgaatcca acttttttat ttctcttagc
    39121 acctctaaac catctttttt tggcattgta atgtcaagca acatcaaatc gggcttttca
    39181 tatttaaata tattacacgc ttcttctcca tcatttgctt ctactaaatt attatagcca
    39241 cttttaccca gagcctcttt aattatcatt ctcataaaaa tagcatcatc tactatcaaa
    39301 attttatttc ccataaaact aactcctcca tatgtacaac aataaacgct tttattttca
    39361 gttattatct atactatctt actatttttc gctacaaaat aaatacattt cattgataaa
    39421 taaaagtaat tacttatgtc atattatgct taattctctt aacataattt ttcaacaaaa
    39481 aaacttatat atctattgta atatatgttt ggtgttttga cgagttatta aaaatataat
    39541 tgtataaaac atcaaaagta atcaaattat aataaaacat aactttatac cttatttata
    39601 tttgtataaa aataattttc agattcatta aaatcatttc tgtagattta tataagattt
    39661 gactttctta atatataata gatagttgtt tatttactta attatatttc tatatatgta
    39721 ttatcgatta aattatattt agctttatac attatttttt atatttttca aattgcatac
    39781 tcataaatcc aaaagtgtta tcacatactt ataatgcttt ttttcatatt tcaaattaaa
    39841 tgacaagtca ttatatttac aagtatcatt ttacaacaaa caatattaaa tgaagaatat
    39901 gtctaaatat tcaaagtgat aatgatactg ttaattatta aaaaagcagt aaatctgtaa
    39961 aagatttact gcttttttaa taattaaact ttctataata aatctactat actcgatact
    40021 tccttcattc aatataatag taacaaatct actttattcc tatgtaaata tgaatttcat
    40081 gtttatttgt atcaaaagta ttactttgat actcttcaaa atcacttaca taagtcctgt
    40141 caaaatccat ttgccaaaac tccaaccaaa aatctcctac ttctttttga cctcctgcta
    40201 taacaaactt tgcatactta cctgctggta taactttact aataataatt tctccaacag
    40261 tattattagt atttaattct tctaaattct tatctttatc agaattacta tttacttcac
    40321 aacatgcaac aaagttatat ggacttgtaa aatcaccctg gtaatctgta tatagaccta
    40381 ttgtcttgtc actcttctta ccctttatag cattatatat acctttgccc ataaattttt
    40441 tccacaattc ccctatatca tttactgctt gtccatcttt atttgtagtt tcctttgata
    40501 ttcctataac tattttctca cttatctcta ctatttcata attcatactt tatacctcac
    40561 tttgttttta ttaatatatt ttactttgaa ctaattcaat tataatttat aatatacgac
    40621 acctttatgt catattttta atataattaa actcagtgag atattataat atacctaata
    40681 aactttttaa tctagcatta tattataagg aataaatttt agacaactcc tttagtctag
    40741 ttattacatt atccctaaca tctttaggtt caagtacttc aacgttgtcg ccaaaggata
    40801 aaatatatcc ataaatccat tcaccaatag gaaattccgt aattacatca tatgtattat
    40861 cttcattttt agttattaaa tctttattaa aatcatcaaa tactctaaaa agcatctttt
    40921 ctttaaacct caatttcaac gttatagtat tttccttaat tactttagag tcattcaagc
    40981 atacttcttc tattaccttt cttgaaaaca cttcttcctt tatagataaa ttccttattc
    41041 tactaattct aaatatccta aaatcatctt ttagcttaca aaatccatac aagtaccaag
    41101 tcttactctt atacataagc ttaagtggtt cgacagttct gtttgtctgg cttgacaaac
    41161 tatttacata attaaaattt ataatattac gccttaaaat agcttctttt atttttgtaa
    41221 atttatcatc ttcattaaaa ttgcttcccc attcagtaaa gtctatttca atccagtttg
    41281 aaaaattctg ctctccaaat attgaaccaa ttttatttac tactgaattt atttctggat
    41341 acttagtcgc ctgtaatgtt ttcagcgcca ctattaaact ctctttatct ttttttgaca
    41401 atatagcctt atctatagaa tattcttcta ttaaagatat acctcctcct ttgcctttca
    41461 tcatatatac tggtactcct gacatagaca gagtttctat atctctatag atggttcttg
    41521 tagaaacttc aaatctatct gccaactctt tagctgttac tagtttttta tttaatagaa
    41581 ttactattat ttctgttaat ctatttattt tcattcatta ccacctacta aaattattaa
    41641 acttatttaa tctaaattaa ttataccaat ttttaagcaa ataaaatctt agaatcttat
    41701 ctagattatt cttatatgat tttatttact atctattatc tttctcactt tggatattat
    41761 tatcttaatt tacttattac tatcttactt aatttactta ttgctatgtc aattccctta
    41821 ttataatatc atttgtcatc attttactta acttgcttat tatcatttac tttattaaat
    41881 ttctatatca aaaattagta tctatactta atacttacaa ttaattcaaa gtctttccat
    41941 agtatttatt ttttattata ctattcattt caatgctttc taaaccactc tcactcattt
    42001 attttaaaat ttcaatttac tatttctcaa ttctatgtta ttatttttaa attttatatc
    42061 actaattttg aagcttttta attattactc atacaatatt taaacaactt tttcataata
    42121 aagccatatt acaatatatt caaaatatgt aatattttag atatttttcg ttgacaatgt
    42181 taaatttttg ttttatcctt aattaaggac atgttattga catttctgaa acttatttga
    42241 aatagttttt ttatttcatt taggaaaacg tattatactt aagaaaacgt attttatcat
    42301 ttcaaataag tacaatattt attcttttgg ggaggaaatc atggaaatta ataaaaaaca
    42361 ttttattcaa gtatttttaa cttgcttaat cttagtagta atatgtgaat ttatagggca
    42421 aagaactata gctattggaa aagcttctat agtactgttc cctatgcttt atgcagttat
    42481 aattggactt ataataacac cagatttatt aggtaaaaaa attaaagcac ttaaaaaagt
    42541 aattggagaa aaagaaataa atattgctgg tgaagttgtt ggaattgcac tagtaatgct
    42601 tggtataaag tatggtacta cagttggacc aaacattgac aagataattc aagccggacc
    42661 agcattcatt gcccaagaat ttggtcatat acttgcacca atcgttgcat tacctcttgc
    42721 attaatgttt ggaatgaaaa gagaagctgt tggagctact gcaagtataa gccgtgaacc
    42781 ttctttagga gttatatcag aaaaatatgg gataaactct ccagaaggta gtggtgtact
    42841 tggtacatat ttaatgggaa cagttcttgg tactatatac tttagtgtcc tgggttcaat
    42901 atctatctac agtggtcttc acccatatgc tttgggaatg gcctgtggtg ttggtagtgg
    42961 aagtatgatg acggcagctg ctggttcatt gtctaccatg gtaccacctg aaatggcaga
    43021 tacaatactt gcctatgctg caacaagcaa tatgatgtct agcataacag gaattatatt
    43081 cttagttttt gtatctttac catttactaa ttttatgtat aagattttag aacctaaatt
    43141 ttcgagaaat aaaaatacta aagaaattaa atctacaaaa ggagagtgct aacaaatgtt
    43201 tgctaattta aatttgaaga aaagttcata tcaattattg gttatgtctg ttattggggt
    43261 tataattctt attggacaaa gaattagcgt tggtacatct atagttacag ctcttcctgg
    43321 tatggtgatg ctaatattag ctgctatggc ggctatgatt ataaaagatt tatttcctaa
    43381 atcaatcttt ccagcttttg gatttgcaac tataataggc cttttactta gtatgccata
    43441 tagtccaaca tctgaagtat tcttaactaa cactaataat attaacttta tggctataac
    43501 tactccacta ctagcttttg caggaatttc tgttggaaac aaaatagaag ctttaaaaga
    43561 aatgtcatgg aaaatagtta taatctcact tattgtattt acaactatat tctttgcatg
    43621 tgcgagtata gctcatatag ttttaagtat tcaaggtaaa atataggagg aatttattat
    43681 gaataaagaa caattaaaat ctctagtaat aaaaactata gatgaaaata gagaaaaaat
    43741 attaaaaata ggtcaaggaa tatacaataa tccagaatat ggatataaag aatttaaaac
    43801 tacggaagct gtttcaaact tttttgagca ggaattaaac ttatctgtag aaaaaaacat
    43861 agcagttaca ggatgtaaag cagatgcaaa ttctagcaag gaaggtcctc atatatctat
    43921 acttggagaa ttggatggta tatcatgtaa agaacataaa gatgctaatg aaataggtgc
    43981 ttctcatact tgtggacata atattcaaat agctggaatg ttaggtgccg ctgttggttt
    44041 agtgaaaagt ggtgttttag aacatttaga tggtaaagta tcttttatgg ctactccagc
    44101 tgaagagttt attgagttgg aatacagaga acaattaaaa aaggaaggaa aaataactta
    44161 ttttggtgga aaacaagagt taataaaaag aggttatttt gatgatatag acatatctat
    44221 gatgtttcat tcttctgatt taggagaaga taaggctcta gttggtcctg aaagtaatgg
    44281 atttgttgga aaaaaagtta aatttatagg taaagaatct catgctggtt ctgctccaca
    44341 tgatggaata aatgctttaa atgcagcaat gcttgctata aataatgtaa atgcacttag
    44401 agaaactttt aaagagtctg aaagagttag attccaccct atcattacaa aaggtggaga
    44461 tatagtaaat gttgttcctg ctgacgttca tatggaatca tatgttagag ctagaactat
    44521 aaatggtatg attgatgcta atgaaagaat aaataaggct ttgatggctg gtgggatggc
    44581 agttggagct gatgttaaga taactgaaat tcctggatat cttccaatat taagatacaa
    44641 aagccttgat aatttattta aaaacaatct tgaagattta ggtctaaagg gaaaagttat
    44701 tgatggtgga gattttacag gttcttttga ttttggagat gtgtctcata taatgcctac
    44761 tcttcaccct atgattggtg gtgtaaaagg agctcttcat acaagggatt ttgaaatagt
    44821 tgatgaagat ttagcttaca tagttcctgc taaagcaatg gcacttacag ttgtagacct
    44881 tctttttgac aatgctaaga atgctaaaga tatattggat gcctttactc cagttatgac
    44941 taaagaagaa tatctaacat tcctagaaaa acacgataaa actttataag tctattttta
    45001 taatacaaaa ttgagtgtct aaagatgaat tttttagttt attagacact cttttttgta
    45061 tgaaatcaaa tatattttta tagttttagt tataaaaaag tctatatcta ttttgagaaa
    45121 gatatcctta ttatcattta ttgttatatc tgcctactat ttgtcctttt aacttttaaa
    45181 caaaataaat accctaatat aggaattaaa ataaaaaata ttatctttaa taaaactcaa
    45241 taaaatcaat aacttaatct tccactagct ttttataaaa ttttgtttta aaattaattt
    45301 taaagattat atactgcaaa gatatattaa atacaattca tcataaatct acttaaagta
    45361 tatttaacta acactactca accagaaaat tcagaaaact gcattgacat aggaaaaagt
    45421 ttattttata ctttttttag gacatattgt ggacacgtct taaatcaaca agcagaattt
    45481 acatgaaagc ttaaccacaa tacttatttt ttaattatat ttttaaatat tagggaggat
    45541 attatgaatg ataacgtagt taagaagaaa aacttttttg acagaacatt aaacagaata
    45601 gaaactgttg gtaataaact accagacccg gttacgatat ttttagggtt atgtgtactt
    45661 ttacttatac tatctagtgt agttggttct atggggatat cagtagttca tcctggtact
    45721 ggagaaacta taactgctgt aaatttattg actgtagaac aacttcaaat tcttttagga
    45781 aacatagtta gcaatttcca aggttttgct cctttaggtc tagttttagt aactatgata
    45841 ggtgctggtg tatgtgataa aacaggactt atgacagcaa caatcaaagc atcagtaagc
    45901 aagattcctg aaacaagagt aactcttgtt gtaatgacta taggtatgct tgccaatata
    45961 gcttcagatg caggtacaat actatttcca ccattagctg cacttgtata tcttggtgtt
    46021 ggtagacatc cacttatagg tttattttct ggatatgcag cagtctgtct aggatttgct
    46081 gcaaacatta tgataagcgt caatgatata cttgctgcaa gttttacagt tccagcagct
    46141 cagatgattg attctggatt tcaagccaat gcaacaatga acttattttt tatgatagca
    46201 tcaacttttg tcctaatact tttggcaaca tgggtaacag aaaaaattgt agctcctaga
    46261 tttggtaaat atgaaggaaa tgcaaaatta gatgttgatg gaagccttag tgatgtagaa
    46321 aagaaagggc ttaaaaaagc tggtataagt atattaatat atgtagctat tatagtagct
    46381 cttagtgtaa tcggtaaaaa accattctta gctgacccgg aaacaggaga tttactatca
    46441 aacaatgctc ctcttatgaa gggtatggta cctataatag cactagcatt ttttatacct
    46501 ggtgttgtat acggaaaaac tataggtaaa ataaagaagg ataaggatgt agtctctata
    46561 atggctagtg caatgagtga tatgggtgga tatataatac tagcatttgc tgcttctcaa
    46621 tttttacaat tattcacaaa tagtaatttg ggtctgatat tagctgtaaa gggtggagaa
    46681 tttttaaaat cagcaggaat aaatggacct ttattattga taggattcat tatattatca
    46741 tgctttataa atttatttat aggtagtgca tctgcaaagt gggctattct tgcacctata
    46801 tttgtaccaa tgtttatgat ggttggatac aatccagcac ttactcagat ggcttatcgt
    46861 ataggtgatt gtataacaaa tccacttagc ccattatttc cgtacttccc tattatacta
    46921 gcattcacaa gaaaatacga taaagatgct ggtatgggta ctgtaattgc taatatgata
    46981 ccatattcta tatcattctt aatagtgtgg actatactat tgatattgtt tatgatattt
    47041 aatattccac taggacctgg aatacttcct tcatatagca tgtaatttat ttaaatcttt
    47101 ctaaaaggag aaataattta tgttggataa aaatagactt ataaataact ttatagacat
    47161 ggttagaatt gatagcccat ctaatcaaga attagaaatg tctaagtggt tggtaaacta
    47221 cttaaaagaa agaaatatag atgccattat agatgatgca ggtgaaaaat atggtggtaa
    47281 cacaggtaat gtcattgcct atataaaggg tgaagaagga agtagaccac tttgtttatg
    47341 tgcacatatg gaccaagttc aaccttgttt aggtgtaaag ccagtactag atggtaatgt
    47401 agttagaagt gatggaacta ctacacttgg tgcagatgat aaagctggaa tagctgctat
    47461 acttgaagct ttagaacatg ttattacaga aaaaatacca catagagata tttatctttg
    47521 ttttacaatc tgtgaggaag ctggtatgca tggtgtcaaa aactttaatc ctgaaaactt
    47581 gccttgtaaa gatatggtga ttttagattc tggtggagct attggttcga tagcatacaa
    47641 agctcctgct caacaatcta taaaaatctc ttttcatgga aagaaagcac atgctggtat
    47701 agaacctgaa aaagggttaa atgctatatt agtagcctct catgcaataa gcaatatgca
    47761 cataggcaga atagattcat tgactacctc aaatataggt aaaatagaag gtggtggagc
    47821 tacaaacata gtaactgata gggttacatt gactgctgaa attaggtctc atatccctga
    47881 aactttagag tatgagctta atcatatgga aaaatgttgt aaggatgctg catctaaatt
    47941 taatactact tatacttttg aacataatat gtcttaccct agttttgaac ttagtagaga
    48001 tagtcatgtt ttcaagttaa gtgaagaagc aataagacaa gtcggtattg ttccaaatcc
    48061 aatggtaatt ggtggtggaa gtgacgcaaa tatattagct aatcttggat ataattgtgc
    48121 tatattaagt ctaggtatgt atgatgtgca cacggttaat gaatatgtaa atatagatga
    48181 attatatgat actgccaaaa tagtttatca tatgattaaa ttataaatat cataatataa
    48241 ctctttagat tataaaaata aaaacctatg tatcttcaac tttacaagtt atatattaaa
    48301 aagttgcttt acataggttt tagtttttta tatagtaatt tattctagca tttttaataa
    48361 taagctttag ttttttatat agtaatctgt tgtaatatat ttcataataa gctttagttt
    48421 tttatatagt aatttgttat agtatttttt ataataagct ttaatatatt atatagtaat
    48481 ttgttgtaga aatttatatg atataatgat ttatacagct ttataaagta tcttaaaaca
    48541 gtatttcagt aatatttttt ggtcttcctc caccaatact agtctctttt gcacatattc
    48601 gacctaaacc tgcatttact attttattta atatacgtct tgcacttctt tcacttacat
    48661 ttagatactc tgctaactct tttgaatcat aaatcttact ttttctattc tcacttatag
    48721 caataatttt tgcaaccgac tcacaactca ttccagtctt tttagatatt tctattacct
    48781 tttcatcaga tagcatcaaa gaataattta attcattttc tgaagctaaa ggtcctctta
    48841 tgttttcatc ttcatctact aaatatatac caatttcttt tgaatctatg gagtatctta
    48901 atgctttatg tgcattattt tcagcctgat acgcagttac tccagtacca attcctatac
    48961 taagagaaaa gcccatgtct tttatctctc tctttagctt gaatagctta tcataattat
    49021 actcattatc agctacccct ttatgaacaa atacaacata atcatttctt ccaagtaaaa
    49081 ataaggaacc ttgaatactt cttacatagt ttactacaag cttatccata tcagattttt
    49141 ttatcatgtc agaataatag ttatctatct tctctttata atctattaga ctcaatattt
    49201 cgacagcaat ttgagaaaat cttgccttgc ttagagcata ttcactcttt accttatcat
    49261 aactttcttt gattaattgt atagtagctt gtaaacgaaa tacaggatag cctctttctt
    49321 ttaattcatt atatactgca ccaaaaccag ttaacattat atctgtctta ttttcttcaa
    49381 ataattttat atgccattct acaagttcag actctcctac ttccaaagag aatggattac
    49441 aaaatacact agttgcttta atatcaaatt ctttaagcgc atcttccaca acatatctat
    49501 caactacatc tatactgaat ttatctaatt ttatatttgc actttttatt gcccaaaatg
    49561 ccttcattat actagtccca cttctcggta caaatgaatg tggcttactt atctcatact
    49621 tagattttat aaattcataa actgcacatc cggtaaatat aatagcatca cattcatctt
    49681 cacatttaga aataacttct attgtatcta ccactttttc tcttacatat attttagtct
    49741 ttaaatcatt gtctatctgt tttaaatcat cctttatctt aaacccagag tctgaaggac
    49801 ctataatacc cactatcata aacttcgctc ctaatccata aatattatac tttttaaaaa
    49861 ttatatcctc actatttttt gcttctattt aattattttg aactactcca tcctacctac
    49921 gtttagaatg gaataattcg cttatttttg ataaagtaac ttctcaaaat catcacttgg
    49981 aataggctta caataataat aaccttgaat tactacacaa tccaaactta ctaaaaattc
    50041 agcttgttct tttgtctcta caccttctgc cactacatcc atatctaaat cttttgccat
    50101 ggctatagtg tgctttaaaa ctattttttc tctatctgtg attccttcac cattaaagaa
    50161 accacaatct atctttaatg tatcaatatt aatatttttt aacatattta atgaagaata
    50221 tgctgaacca aagtcatcca tatttaaaac aataccatcc attctaaggt cagctattac
    50281 cttagtgaat aattttatat ttttaataaa tagactttct gtaagctcta attctaaaaa
    50341 agattttggt ataccatatt tatttattaa gcttaaaaca atttctttaa aatgtggatt
    50401 atgcaaatgt aatcttgata catttacaga gataggaact ggctcttcac ctaaatctat
    50461 ccattttcta atcaaagaac atacttgttc ccatacatac atgtctaatt tgataataaa
    50521 cccattcttt tcaaatagtg aaataaattt aattggaggt attatacctt tttctggatg
    50581 aacccatcta accaatgcct ctgccccaac aattttattt gtattaagat tatacttagg
    50641 ttgtaaatat acatgaaatt gtccattttc aagtgcatat tccatttctc tttccatatg
    50701 tttttcttca agtgcatcat ttcttatagt atcatcataa aatatataat gattgatact
    50761 ttgtttcttt acttttttgt gagcatatcc tgccatttca catgcacttg taattgggat
    50821 atggttatcc aaaattttat aaaccccaaa acatggtact aacatatatt caaatttttt
    50881 cctattcaag ttatttttaa tattataaat tactttatga atctctctat cagagtaact
    50941 ctcataaaaa atgcaaaata catctgcata catacgacaa catataccat tagaaccaat
    51001 gtttttttga atcaattctg caacatatat taaggcttta tctcctcctc taattccata
    51061 aatatcatta attactttga acttatctat atccatcatt ataattgcat agcgcttgcc
    51121 aggatatctt ttcagcatta agcttgtttg ttcacaaaaa ctttcataat tgtataatcc
    51181 tgttaatgta tccttttggt ttttatgtat ttgcataaga taatctatat ttttaatagc
    51241 aactaaaata tgtgtttgtt tctcacctaa attattttta ctgctaatct tcagaatata
    51301 aagtaatgcc caatggtact tttcatctat tcctaagtgt ctatactcaa aatttagttc
    51361 taaatcacct tgtttgctat tattaggact atcaatagat tttaaaagga ggttatcatc
    51421 aaataatatt atatcatcag ggtgaatcaa atgcttttta atgtatgaga aaattttctc
    51481 aatattctct tttataggaa aatttaaaat attgctctct gattgataaa ttggagtaat
    51541 taaatttgta tccatgcaaa tagataaaat tatatcatat gtattataag ctaatttttc
    51601 ataagcctta gaataccctt ttatcattaa atcatcaaaa tacacttcat tatctaaatc
    51661 tctacattta agtgaaatat tatttgttga atcgcttaaa tcactaacta ccttcatttc
    51721 attatttcta agttcgattt tattatagta tcgtttctta tcttggtaca tcctctcatc
    51781 agcaacttta attaacttat gtatatcaat atcatcttca ctccaaatac ttcctactgc
    51841 tgcactacat tccatgttat ctttaagttc ttcagttagc caacttacta attcttcaaa
    51901 taattgtttt gagatatctt cacataatac aacaaactca tctcctccaa tacggtaaac
    51961 ataataagaa tgaaagtatt tttgtatcat tacactgact gacataatga tggcatctcc
    52021 actagcatgt ccaaagttat cattaatatc ttttaatcca tttatatcta tgaatacaac
    52081 tcctatagat ttaactttgt ctttttgaaa agtatctata tacttaatat atctatttct
    52141 attatatgca ctagttaaga aatcatagta gctcatataa tttaatttat tttctacttt
    52201 tctttttttc atttcagtta ataaaaaata agatagggat gtcaaaagag aggtgtctcc
    52261 aacagcctta cgtggattat cgactccaat aaatcctatt attttatcat cttcttttaa
    52321 tgaagacgcc attaaacttt tgattttttg aggttttaaa atttcatatt ccattggatg
    52381 ctcttctttt atatcttcta catcgtcaat tattataaat cctttttgct taaataataa
    52441 aaaccaattt tttaattcct taatatcaag atttgttagt aactgttttt gttcatcaac
    52501 accttcatta caccattcat atgtattaat tacttttttt ctatcttctg atacttcaaa
    52561 aacatatgct ctatcagctt tatgaaattt accaatactg cttaatacaa ggtctacagc
    52621 atcagaaaaa ctagattctg ttataagatg tttaatacat ccaactaata gctcctttat
    52681 ctctaacttt tctgatattg atttacttat attttccttt tctgtaatat caagagctat
    52741 ttctatcctt gcaagtttac cttcccattt aattaacttg tcctttaata taaagtgtct
    52801 atttattaga gtatttgtat tttcccatac gtaatatcca tcttctttta aaatagaatt
    52861 tgtacaaaat tcgcaaggag agtctctacc ttgtattgct tcataacatt tcatattaga
    52921 tatatcatta atcctcagtg cctttttccc aatttcatta atatataaaa gttcatatgt
    52981 atctaaagaa gaaacatata caatttcatc caattcatct attaaattta ttacatccat
    53041 ttatatatat ctccttttat tcattttccc agattgaatt ttaaatcttt taaaattttg
    53101 ctatgtattt agcaatgatg ttatgcttct ttatatttta aaatagcacc ttaataaagt
    53161 tctatttttt agtcaataga gttattatcg tgtcaattgt acagtagagc tttgtaatac
    53221 ttaatttaat atatctataa ttaattatcg tattgtgtat ttacaattaa tcatcatata
    53281 aataataaat ctccacttca attaagtatt ccaatcatat agaaagataa tacttcattc
    53341 atttaaaaat ataaaactat tatatattaa gatttctcaa tattaataag ttatttagtt
    53401 tgttactttt atatattata taatatcaca aaggctgaca taaaaagata aaaagggcaa
    53461 t
//
LOCUS       DBGJFK010000022        52979 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.022, whole genome shotgun sequence.
ACCESSION   DBGJFK010000022 DBGJFK010000000
VERSION     DBGJFK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.022"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(352..1296)
                     /locus_tag="ACOIAP_001523"
     CDS             complement(352..1296)
                     /locus_tag="ACOIAP_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HGZ2638411.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVED
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFIKKYEKNEQFSFEICDTHQELIVDSDVVISTVTYTDEYLSEYKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQGKGRENDDERIISY
                     NIGLSIHDILFANKIYELCEILNCEEIELKEPKEKYWI"
     gene            complement(1316..2548)
                     /locus_tag="ACOIAP_001524"
     CDS             complement(1316..2548)
                     /locus_tag="ACOIAP_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGZ2638412.1"
                     /translation="MKRLMILGSIKYFENIVMSAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYVANELNLPCVISCNQLESVT
                     NKAVMKKYFKNNGIPTTDYCIVESLKDLEKIQELNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEVSQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEINFDEIKKYNMHLSKCVYALPIYIKPGTI
                     KKINNVDKIESLDYVTQILLLVKEGDTIGLYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            complement(2640..3635)
                     /locus_tag="ACOIAP_001525"
     CDS             complement(2640..3635)
                     /locus_tag="ACOIAP_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0044038 - cell wall macromolecule
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HGZ2638413.1"
                     /translation="MNNIRINKFEKSCEKHWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIIYKGEEILAVVPACEIYENGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQSFNKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DIVANFRYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSIEEL
                     LDFKNNRLKDIVEFYAVYIDGIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKNALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            complement(3644..5758)
                     /locus_tag="ACOIAP_001526"
     CDS             complement(3644..5758)
                     /locus_tag="ACOIAP_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2638414.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIYDILEIFKKNADVGMIGVAGVKDI
                     PVNGIWWDSDKKVGKVYDSHTGKMDIYEFSNFDECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIIPKQNKPWCMHDSGVANINNGYDEYRIRFVKEYI
                     NLDLDRENFYEFDEKKASTILKSNKHVMDCMKEELTEQLILKNYKDVLDIVSKIARFS
                     VFNHTGLYSCEKCERALIECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPEWLLKAIDDSGGEIISLDLISDDYLKRAMALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGASIADIVIDFSE
                     ASQLITLNKRGIDKSEILPILLKEKEVFSKSEIRKQYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENIYWKTLSNVTDNRVICFGTTTNIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDRFDYKNIKEVID
                     MIKRYNTSEFDRNKIKEKQSGIKHFVIDKHCIEIKNYIDKIYNEANHHKVKCDLYKND
                     EIEEYQLFVALYGYMVKNKNMS"
     gene            complement(5751..7628)
                     /locus_tag="ACOIAP_001527"
     CDS             complement(5751..7628)
                     /locus_tag="ACOIAP_001527"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2638415.1"
                     /translation="MNTPILVNEKSKDIIKDWQYTYTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKDKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNSKNLGFPKGCNQGIE
                     LANGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSVE
                     EMFIFAQKINKSNINLWKYRLKLVGFCMLIKKSVIDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCKDTFIHHFGSISFKENRNKYTDIMDINRRKFETKWGFNPEYSGIIRT
                     DLISKIDDSPETNINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYKKNFFDYIILGDVLEHLIDPWKIVNKLKQYLKKDGYLVSSIPNVMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITAISMPLSEID
                     NRFIDTMCKESCKEMRQQYESYQYIVKATKSIDTKKYSSISMVNLKYALMRIDNELDI
                     DGNLSYIFDNYNITEPCFVDDIEYLVDTFVINKVTLLNRLGVEAFNRGLGDFSINMFM
                     KVLEMDRDDIDSIYNITSVLCELEEFDIAYNLIKNSSEKVQSESDIQEILYFIEGKRY
                     E"
     gene            complement(7652..9793)
                     /locus_tag="ACOIAP_001528"
     CDS             complement(7652..9793)
                     /locus_tag="ACOIAP_001528"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2638416.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRDSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFEELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLERYESVISEYNNIEDIEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKLDLLDIFYEMEYVWIEKYLKYLLALERSFNLALYKYIISCPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLNIKNKVNSANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFRDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDVKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            complement(9886..10758)
                     /locus_tag="ACOIAP_001529"
     CDS             complement(9886..10758)
                     /locus_tag="ACOIAP_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HGZ2638417.1"
                     /translation="MRVNTNVSALIANNQMGRNVSAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNVDGASGTDAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            complement(10859..11194)
                     /locus_tag="ACOIAP_001530"
     CDS             complement(10859..11194)
                     /locus_tag="ACOIAP_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HGZ2638418.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISSKLDERQEIINSV
                     SEIDRNDFIQLYNKMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYSLNRE
                     KVNIFNKKV"
     gene            complement(11197..12720)
                     /gene="fliD"
                     /locus_tag="ACOIAP_001531"
     CDS             complement(11197..12720)
                     /gene="fliD"
                     /locus_tag="ACOIAP_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HGZ2638419.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNIIQESKDLYDKYLSVDSPNSIVSQKAYSSTKITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FVSDAGGNKLASVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMKSFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKSLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            complement(12741..13097)
                     /gene="fliS"
                     /locus_tag="ACOIAP_001532"
     CDS             complement(12741..13097)
                     /gene="fliS"
                     /locus_tag="ACOIAP_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HGZ2638420.1"
                     /translation="MELNLAELGKLSKEELLLMLVDATVKYTNISKDALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNKIKI"
     gene            complement(13097..13492)
                     /gene="fliS"
                     /locus_tag="ACOIAP_001533"
     CDS             complement(13097..13492)
                     /gene="fliS"
                     /locus_tag="ACOIAP_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HGZ2638421.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQRAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            complement(13514..13726)
                     /gene="csrA"
                     /locus_tag="ACOIAP_001534"
     CDS             complement(13514..13726)
                     /gene="csrA"
                     /locus_tag="ACOIAP_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HGZ2638422.1"
                     /translation="MLVISRKKDEAVLIGENIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNINILKSLK"
     gene            complement(13720..14112)
                     /gene="fliW"
                     /locus_tag="ACOIAP_001535"
     CDS             complement(13720..14112)
                     /gene="fliW"
                     /locus_tag="ACOIAP_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006417 - regulation of translation
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HGZ2638423.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDSLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVMLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            complement(14129..15061)
                     /gene="flgL"
                     /locus_tag="ACOIAP_001536"
     CDS             complement(14129..15061)
                     /gene="flgL"
                     /locus_tag="ACOIAP_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HGZ2638424.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMEIYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKIKEIANALNATHEGKYIFSGSNTGIPPVECVDNADGSVSLKFN
                     SSIDLNKLKDSLSMDVAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGEMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKEILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFSVSILDYI"
     gene            complement(15080..16390)
                     /gene="flgK"
                     /locus_tag="ACOIAP_001537"
     CDS             complement(15080..16390)
                     /gene="flgK"
                     /locus_tag="ACOIAP_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HGZ2638425.1"
                     /translation="MAGLFSILNTANSGMNSHQKAIQTISHNISNLDTEGYSRQRTEF
                     ATNSPMYMPSLSNSIGRGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKGDIDSNIDTEIKQINEMLKSLEDLNKSIDIISGSGSMPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNADGTWKTGVSGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVRDFFVTSNVDGEDIIKVNPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAELVGLDSKKVNQDEVNQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            complement(16408..16824)
                     /locus_tag="ACOIAP_001538"
     CDS             complement(16408..16824)
                     /locus_tag="ACOIAP_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HGZ2638426.1"
                     /translation="MITDLKVIMYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSKDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPVDKQTTTYNSYGNIRK"
     gene            complement(16829..17104)
                     /gene="flgM"
                     /locus_tag="ACOIAP_001539"
     CDS             complement(16829..17104)
                     /gene="flgM"
                     /locus_tag="ACOIAP_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HGZ2638427.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGVKKVEDVKKINKTDKIELSKFAK
                     EMASVSNMSDESIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            complement(17256..17570)
                     /locus_tag="ACOIAP_001540"
     CDS             complement(17256..17570)
                     /locus_tag="ACOIAP_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HGZ2638428.1"
                     /translation="MNSKKEDIYELNFGQLIEEQSGIIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLNKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     IN"
     gene            complement(17594..18022)
                     /locus_tag="ACOIAP_001541"
     CDS             complement(17594..18022)
                     /locus_tag="ACOIAP_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HGZ2638429.1"
                     /translation="MGINIDKLKISPSINIEVKKLKENNKFSDRLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            complement(18031..18699)
                     /locus_tag="ACOIAP_001542"
     CDS             complement(18031..18699)
                     /locus_tag="ACOIAP_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HGZ2638430.1"
                     /translation="MNEISSLINILALTQLSGSNNTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNGYNISSNSENLFNELENVVNNTTSRFIDVDTKDKNVKLRIENAVEQA
                     SKKYNVDANLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            complement(18737..19720)
                     /gene="rfbB"
                     /locus_tag="ACOIAP_001543"
     CDS             complement(18737..19720)
                     /gene="rfbB"
                     /locus_tag="ACOIAP_001543"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGZ2638431.1"
                     /translation="MKKILITGGAGFIGSNFVHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVRGDISNREQMYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSPINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLKVVKIILNLLGKSEDLISYVND
                     RPGHDLRYAIDASKIQNELGWKAKYDFDFGIKETVKWYIENESWWKSVLSV"
     gene            complement(19758..20315)
                     /gene="rfbC"
                     /locus_tag="ACOIAP_001544"
     CDS             complement(19758..20315)
                     /gene="rfbC"
                     /locus_tag="ACOIAP_001544"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HGZ2638432.1"
                     /translation="MGKINVIKTKIEGLYIVEPSVFCDERGYFMESYNKRDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVRYPQGKLVRVTEGEVFDVAVDLRKDSKTFGEWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFNYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICIRR"
     gene            complement(20364..21233)
                     /gene="rfbA"
                     /locus_tag="ACOIAP_001545"
     CDS             complement(20364..21233)
                     /gene="rfbA"
                     /locus_tag="ACOIAP_001545"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGZ2638433.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLKITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLEKAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYKKGYISRAQLMELAKPLIKTE
                     YGQYLLKLASEDM"
     gene            complement(21342..22214)
                     /gene="rfbD"
                     /locus_tag="ACOIAP_001546"
     CDS             complement(21342..22214)
                     /gene="rfbD"
                     /locus_tag="ACOIAP_001546"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGZ2638434.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSMSQPKYAILATTRNDFDI
                     YNQTNVDNFILNNKPDVVVNCAAYTKVDACEDNIETAYKVNALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDSKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLTKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFELKNIDIKVNPIKSNEFKCKAQRPLYSVLDNFMLKLIGLNSFRNWEE
                     SIEEYLERYDMNEE"
     gene            complement(22418..26224)
                     /locus_tag="ACOIAP_001547"
     CDS             complement(22418..26224)
                     /locus_tag="ACOIAP_001547"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGZ2638435.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDEDGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     RVTKVDEENTFFSSNEIVKDVKCASMKDKFIKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKIDSKVVMLCVNKAENDVIDFDELK
                     RNLDKVRELIHGNKILSTYALGFAGVGEAISKMAFGNKIGFKFSEETEKAFKDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKSHCSTLEPI
                     FPTKAEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NANIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYNIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVFKNIIGEKDQKIFES
                     GVKYFR"
     gene            complement(26249..27499)
                     /gene="purD"
                     /locus_tag="ACOIAP_001548"
     CDS             complement(26249..27499)
                     /gene="purD"
                     /locus_tag="ACOIAP_001548"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGZ2638436.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDNFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANRVKETVLEKTLEGFKKDGLDFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMESILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMLDGNLVTNGGRVIGITAKSATVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            complement(27510..29042)
                     /gene="purH"
                     /locus_tag="ACOIAP_001549"
     CDS             complement(27510..29042)
                     /gene="purH"
                     /locus_tag="ACOIAP_001549"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGZ2638437.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKAKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            complement(29035..29628)
                     /gene="purN"
                     /locus_tag="ACOIAP_001550"
     CDS             complement(29035..29628)
                     /gene="purN"
                     /locus_tag="ACOIAP_001550"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGZ2638438.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQDAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            complement(29622..30698)
                     /gene="purM"
                     /locus_tag="ACOIAP_001551"
     CDS             complement(29622..30698)
                     /gene="purM"
                     /locus_tag="ACOIAP_001551"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGZ2638439.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHEIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVNERELHKSFNMGIGLVLIVDKANADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            complement(30692..32059)
                     /gene="purF"
                     /locus_tag="ACOIAP_001552"
     CDS             complement(30692..32059)
                     /gene="purF"
                     /locus_tag="ACOIAP_001552"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGZ2638440.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKESELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            complement(32071..32769)
                     /gene="purC"
                     /locus_tag="ACOIAP_001553"
     CDS             complement(32071..32769)
                     /gene="purC"
                     /locus_tag="ACOIAP_001553"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006772094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGZ2638441.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            complement(32775..33251)
                     /gene="purE"
                     /locus_tag="ACOIAP_001554"
     CDS             complement(32775..33251)
                     /gene="purE"
                     /locus_tag="ACOIAP_001554"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGZ2638442.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     STFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            33701..34213
                     /locus_tag="ACOIAP_001555"
     CDS             33701..34213
                     /locus_tag="ACOIAP_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2638443.1"
                     /translation="MLEVIKNRRSIRAYINKSVEEEKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKKLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWVGVFPKNKVVNKVRQTLDLPVKLVPYSLISIGYSEEKNEFIDRFDEN
                     KIHRNIYKNR"
     gene            34763..34978
                     /locus_tag="ACOIAP_001556"
     CDS             34763..34978
                     /locus_tag="ACOIAP_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638444.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            34984..35277
                     /locus_tag="ACOIAP_001557"
     CDS             34984..35277
                     /locus_tag="ACOIAP_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HGZ2638445.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWFKPYDKPIQQLTCSYKESQNVID"
     gene            complement(35459..36172)
                     /locus_tag="ACOIAP_001558"
     CDS             complement(35459..36172)
                     /locus_tag="ACOIAP_001558"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2638446.1"
                     /translation="MINLIFDVDDTLYNQLTPFYIAYNKVFSSIKNISIEDLYMSSRK
                     YSDEVFHMTENGEMAIKEMHIYRIMKAFEELGTSITEKDAQSFQDEYIYQQSQITLIP
                     EVEWVLNFSKERNINLGIITNGPSTHQRMKLKQLNIENWVDKNNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYMGDSYRNDVLGAKKAGWKSIWLNHRRHEVEGVFYKPDFL
                     ILEHKDLMSLFIKICSKKC"
     gene            complement(36260..37525)
                     /locus_tag="ACOIAP_001559"
     CDS             complement(36260..37525)
                     /locus_tag="ACOIAP_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HGZ2638447.1"
                     /translation="MKKLPIKTVVQRLLELQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKIADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPEIGYEVGTEETNGGLTSTETYETFITRLKVELDKRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SSIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVDKTSNIRHVLLVNAIECGRWRK
                     WVIGEQKNLTTEDIFKNEVLSNEILDIAGHYTFNNDDVKKEIEVLYANLSKNNIDGQR
                     FVIDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            complement(37629..37937)
                     /locus_tag="ACOIAP_001560"
     CDS             complement(37629..37937)
                     /locus_tag="ACOIAP_001560"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HGZ2638448.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKEIEEATCVILTNDVEIRNMERFKGKKVVRMSVSDIIKKSDALIKKIKDTFQ
                     "
     gene            complement(38008..39063)
                     /locus_tag="ACOIAP_001561"
     CDS             complement(38008..39063)
                     /locus_tag="ACOIAP_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HGZ2638449.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMVGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAILMKLVKKDVKEDE
                     EIEEDLDDSIELIFEEL"
     gene            complement(39065..39517)
                     /locus_tag="ACOIAP_001562"
     CDS             complement(39065..39517)
                     /locus_tag="ACOIAP_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2638450.1"
                     /translation="MSKLVNVKCSFKIHANSKEEAIISLVDVVSKEGYLRDKNQFLED
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEGED"
     gene            complement(39514..41544)
                     /locus_tag="ACOIAP_001563"
     CDS             complement(39514..41544)
                     /locus_tag="ACOIAP_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2638451.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKPVIQKMNKGVLIIPDNFQVVCINNNEYVFSLTERVSIMKIISMFKIENLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKAFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGISLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESVSLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLNQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLINDYQINIVDSIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     VICQELGYSDERALSRQLNLGDLIGIDTIRIIDEDMKWEDAVKISSNILANCDFVSSQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVRIIF
                     CLASKDKKEQIPAIINLTKMVYKTNFISMLESAKTKEEAEGLIHKYEKEVTV"
     gene            complement(41809..44037)
                     /locus_tag="ACOIAP_001564"
     CDS             complement(41809..44037)
                     /locus_tag="ACOIAP_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2638452.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISSKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDIGI
                     IDLEGKAEFLSGKKFDLKNTDSYKKGIEGKEYSEVIESMGFVFYSVPIFNDNHEVSSI
                     LIGVSNKESMDEILNIDNFNGEGTIEIINSQGRPLFIGKNTELIKDLGHKYKSSGDEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYYPITKGLNDWHFVLIVPEDAVLGELNK
                     LNSFTIIMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSILVKP
                     LILESPDSTYMMVAINIKDFKLINDCFGSKKGNLTLKHLYNVLYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADINYFNKNRENPYFLRISAGIYTIENHNEDLIT
                     IQDHANTARKSFNKAHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKLICNKYNVPTYLIDLELTESIFLENPEAVD
                     IIDDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFEDFAYENNKIK
                     NI"
     gene            44686..48114
                     /gene="uvrA"
                     /locus_tag="ACOIAP_001565"
     CDS             44686..48114
                     /gene="uvrA"
                     /locus_tag="ACOIAP_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGZ2638453.1"
                     /translation="MIINNYQNQSIITNPKKFENEYQYLPDTPIELLKVVQNLIIHGD
                     QGKLYGISFNKQQSDEELLRTVPQMLKRIFEINSNSLTIPRTPKQRLVGMCRDYSLLL
                     VSFLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTATKRWIKIDAQIDDIQKNYF
                     QINFDAHDVRRIDGFLTGSEAWIKCRQEHTHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNKKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELANPLELEKKFKFTKAINKPIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNKITVITGVSGSGKSSLAFDTIYEEGKRRYFENLGNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGNQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKTPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESRGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELTNQLQQKELSLVNDILTELKIRVSYLLK
                     VGLSYLSTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPNAGIKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPNKNYTELTGFDAIDDFILMDQTAIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYIADQWVTCNKC
                     QGKRYKKEILSIQYKGKAIADILDMEVAEAKTFFSDCSDIYRKLYLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGMNGGEIVASGTPDEIKVNPNSITGHFI"
     gene            48299..49132
                     /locus_tag="ACOIAP_001566"
     CDS             48299..49132
                     /locus_tag="ACOIAP_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2638454.1"
                     /translation="MSWKHIKIPNGDTMIFCNSFITSKLSMNIIVTHTPIVTTLEMQK
                     AYEPFTKYNVNIFAFDFSGTGKSDGYEKDFSRNSIIKDLDSIITYIEKNYSSNIHLYG
                     NTGIGGMFAQYYACSDNKLKSFAQFACVDYKNTTGVGYPYLTVKLLNLFFKFLPNFHI
                     TVKPPKYKGYNEVYDNEFYKIFEEKNPHIWKNSTKIINTMLECFIAEDSKIKDGVNIP
                     TLVFKTLHDRYFKTQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVEN
                     Q"
     gene            complement(49261..49827)
                     /locus_tag="ACOIAP_001567"
     CDS             complement(49261..49827)
                     /locus_tag="ACOIAP_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HGZ2638455.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(49824..50387)
                     /locus_tag="ACOIAP_001568"
     CDS             complement(49824..50387)
                     /locus_tag="ACOIAP_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HGZ2638456.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKHFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCCVCVMQVFYKKRKNK"
     gene            50507..51382
                     /locus_tag="ACOIAP_001569"
     CDS             50507..51382
                     /locus_tag="ACOIAP_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2638457.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETSLFDRLPRGVCLTRCGISLLEEARSILTACRNLDKRISRLEECTPINIVSSITIAS
                     FLLPPILSRLKNLFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSEQTLSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPIWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLLHKKLRLIELDGIDMENKMLAILHKDKNI
                     TQPLKIILDNISNVL"
     gene            complement(51530..52693)
                     /locus_tag="ACOIAP_001570"
     CDS             complement(51530..52693)
                     /locus_tag="ACOIAP_001570"
                     /inference="COORDINATES: protein motif:HMM:NF012376.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGZ2638458.1"
                     /translation="MDSYFSARNKDIDSNTERYIETPISKDMKEVGYDVAVLGNHEFI
                     SNNKFYLDNMISDFEKQKINILSANTYKKNGDSYTKPYIIKNINTPEGNVKLGILGLT
                     IKEVGERKQWKDGKLVDSKSLELKDQEGYNGELYMNDLVEDAKKWVSIMEKEKPDIIV
                     AVAHTGEKPKKPRNPGNRIQDLAQQVDGIDAIVAGHNHVQIEQHDYKNKSGENVIVTE
                     PGKHGECISKINFKLEKTNDKWNIVDKSSKLIKFEKNQESDKFGEFISSINKVSKDKK
                     EIRLSEVKTPEWDKIYVFKSGTSADDIYKTIGYKWRNISSPKGDDMVQIVVMNNNKPV
                     SYVYGEAEVMPINIKCDESEYKDNVVTIYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(52835..>52979)
                     /locus_tag="ACOIAP_001571"
     CDS             complement(52835..>52979)
                     /locus_tag="ACOIAP_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HGZ2638459.1"
                     /translation="GYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLITI
                     QNK"
BASE COUNT        17121 a         9361 c         5683 g        20814 t
ORIGIN      
        1 tttcatcctt atgttttagt ttggttagct ttaggggttt ttagcaattc aagtagtatt
       61 ggataggttc tatcctatct ctacatatag gtttccctat atgctgacta ttttagctac
      121 taactcataa ctaaagtcac aagtgtgcgt agctattttt taatcaaaag gtattacttt
      181 atttgattct aatgcaacta aatttcctat atattcattt ccaatagata cgaacttaat
      241 taaattatat ttatccataa atttatctat cctattcata ctaattttct aacaatatat
      301 tacttcatat tcatatttaa aataaattac cataaatatg aatgaaataa actatatcca
      361 atatttttct tttggttctt ttaattctat ctcttcacaa tttagtattt cacacaattc
      421 gtaaatttta tttgcaaata atatatcatg tattgacaaa cctatattgt aagatattat
      481 tctctcatca tcattttctc ttcctttacc ttgtttactt aaaacatcat aaaattcaca
      541 agaatactta tatctatcta tattttctag gtgtttcaaa tgattataat catctaaata
      601 taccttatca aatagataat caacatttcc aaatcccata acatgtacag gtaataataa
      661 agcacctttt ttaaaccatt tatattctga taaatattca tctgtatatg tcacagtaga
      721 aataactaca tctgaatcta caataagctc ttgatgtgta tcacatattt caaaactaaa
      781 ttgttcattt ttttcatact tttttataaa tgactctgct tggtctttat atttaagtaa
      841 ctttatattt atatttttat ctttaagagt atacgaaagc atattcatta tagcagaagc
      901 agttacacct aaacccataa tagcaatagt attaaaatct tttttagcaa atgtatcaat
      961 agccaaggca gcaacagcag cagtcctaaa agctgtaata taattaccat ccaaaatagc
     1021 ctttaattta gcatcttcca tattatatag aaatatctct gaatttaaac ttggatttct
     1081 ccctggcaac cttgtaacca tttttattcc accaatcata tgattatgat ttagggaagg
     1141 cattacattg taaaatacat gtccatcttc taccatgctt atttttggtg gtaattgaca
     1201 atcttttttt gttaaaaagg attcttttat ccactcatac ccttgtttct gagaaatgtt
     1261 taatgacata atttgttcat gagttatcag cttcatatct atcatactcc cttatttaaa
     1321 aattttctat catattctca ttattttcat caagtatttc tatcatttca tgaatacatt
     1381 tcttctttat atttgcatca aatatattat ttgctattcc ataaactctt ccacaatcct
     1441 gtctctcatc ttcatataat cctattgtat ctccttcttt tactagtaat agaatttgag
     1501 tgacataatc taagctttct attttatcta cattatttat cttttttatt gtcccaggtt
     1561 ttatgtatat tggtaatgca tatacacatt ttgatagatg catattatat ttctttattt
     1621 catcaaaatt tatttcatta ttcacactaa agtttgcaaa taagcttcct atgtctaaat
     1681 ctgttatttg agaaatagcc atatagtcac aacctccagg taatcttggc attacttcag
     1741 atacctttat tccatatgct cccactaaca tttgtacata aagaggtcca ttttttatat
     1801 caaaagcctg tgttatattt tgatatatag attttatttc ttcctcatat tgaaaacagt
     1861 actttgatgg ataaattaat ctatctggtt ttccagctct tcctgtatgt atatttacaa
     1921 gctctctatc tccaatataa aatacatgag actctccatt atgaacccaa gctagacctt
     1981 gtatttcctc actttcataa aattcctcaa ttatgacttg tccatcttgt gaaacttcct
     2041 tagaatattc aaacttttct attaattctt ctatatttga tacaaaatat acaccccttg
     2101 aaccatagcc atcaacaggt tttattacga gtggaaaatt taattcttgt attttttcta
     2161 aatcttttag actttcaaca atacaataat cagttgtagg tattccattg tttttaaaat
     2221 attttttcat aacagcctta ttggttacag attcaagttg attgcaagaa attacacatg
     2281 gtaaatttag ttcatttgca acataaacat atggtttcat taaagaatct gtaaatccag
     2341 ttaaaattcc atctatcttt ttatctatag ctatactttt tattttatca aaatcaaata
     2401 catcaacatc tattgcttca tcacaaatct ttttagcagg agtatcaatt ctattatcac
     2461 aaacaattgt gtatattcct tcttttttag ctgacataac aatattctca aaatacttaa
     2521 ttgagcctaa aatcattaat cttttcatat ataaaccttc tttataaact aattattttt
     2581 atctaagatt agagtactat atatttacta tactctaaaa actctctaaa acattattat
     2641 cacttattta tatttttata gtacgttctg ttgcaaattg cacttgagcc aaaaccttct
     2701 ttaaatgtag ctaaaccctc gtctaagtat ttacctctat ttagagtgct aattccaaaa
     2761 gaaagatact taaaatttct ctctaaagca ttttttatta gattataata taaaaatatc
     2821 attggataat atttattata tgtcgaattt gatgctagat attgagtatg ataaactctt
     2881 tcttgaaagt taaataccat actcccacaa atcataatgc catcaatata tactgcataa
     2941 aattctacaa tatcttttaa cctattattt ttaaagtcca gaagttcttc tattgaatgt
     3001 attactttag ctcctttact atctaaacaa ttagaaagta aattaaaaaa acaaactata
     3061 tcttcatcac tatacagtct tttaaaggta agattgttct tcaaagaata tttaaaatct
     3121 cttcttttac tatatctaaa attagctact atatcttctt tatacttact taattctaaa
     3181 aacatactta attcatcata aaacatgtaa ttattcttaa atagaaaata ttctagtaat
     3241 gaagtatcct ccttacaaaa tattcttgat gtatttttta aatatacttt attgaaactt
     3301 tgttcttgta aatatatttc taacttattt gtaatagcat ttacatgcct aatatcatta
     3361 aaaccacttc ttattataat acctccaaaa gtgcttccta aatgagaaaa aaatattctt
     3421 tcaccatttt cataaatttc acatgcaggt acgactgcta gtatttcttc acctttatat
     3481 attattaatg agtggtcagt aaattttccc tcttcatgat aattaaggaa atttctagtt
     3541 tgcagaaatg taccatttat agatttattt tctacaaaat aatcccagtg tttttcacag
     3601 cttttttcaa atttattgat acgaatattg ttcattttac cacctatgac atgtttttat
     3661 tttttaccat ataaccatat aatgctacaa aaagctgata ttcttcgatt tcatcatttt
     3721 tatataaatc acacttaact ttatgatggt tagcttcatt atatattttg tctatatagt
     3781 tttttatttc aatacagtgt ttgtctataa caaaatgttt tattcctgat tgtttttctt
     3841 ttatcttatt cctgtcaaat tcactagtat tgtacctttt tatcatgtct ataacctctt
     3901 ttatattctt ataatcaaac ctatctataa aattccacat attcgtaaaa attggtgaaa
     3961 cttcattttt aaacttaaca ggaattaaat catataaaat tgcatctaat tttgaagtgt
     4021 gacttcctac catgaaagac tctagatata tatccgaaat cttataaaaa tcgtctatat
     4081 ttgttgtcgt cccaaaacat ataactctat tatctgtaac gttacttaga gttttccaat
     4141 agatattctc tgtatcaact cctacaacaa taataattgt attatccgta ttttcaatca
     4201 atgttttagc aattttaaag taattaatat catttacact attgtatttt ctttcactag
     4261 caatagtcaa tattattgtc acatcatcct ccaaattata ttgttttcta atttcagatt
     4321 ttgaaaatac ttctttttct tttaatagaa ttggtaatat ttcagattta tctatacctc
     4381 ttttattcaa tgtaattagt tgactagctt cactaaagtc aataacaata tccgcaatac
     4441 ttgcccctaa ccaaaaagtg ctgtcataat gattaacatg taaaataggt attttcccat
     4501 caactccaaa agcaacaaca ggtattgtat cccacatatg aacatataaa ataactatat
     4561 cagcccagtc ataagctatt tttctcaaag ccatagctct ttttaaataa tcatctgaaa
     4621 ttaaatctaa agatataatt tcgccaccac tatcatctat tgcttttaat aaccattctg
     4681 ggagtgtgtc tgattgccat gtagttacaa ctgaatgaac agagtctttg tcaatctcaa
     4741 tccagttttt aactagtctt gtatgacctc ctgttgaata tccttcactt aaaacatgta
     4801 atacttttct tctttttaaa tctttttttg taaataattt cgtattttct atttctggta
     4861 aattatttgc acattctatt aatgctctct cgcatttttc acaagaatac agtccagtat
     4921 gattaaaaac agaaaaacga gcaattttag aaacaatatc taaaacatcc ttataattct
     4981 ttaatattaa ttgttctgta agttcctctt tcatacaatc cattacatgc ttattactct
     5041 taagtatggt acttgctttc ttctcatcaa attcataaaa attctctcta tctaaatcaa
     5101 gatttatgta ctcttttaca aatcttatcc tatattcatc atagccatta tttatatttg
     5161 ctactccaga atcatgcata caccaaggct tattctgttt tggtataata actttgtatt
     5221 tattttgtct aaactccata ctctgtgaca aatcataaaa atgccatcca tcaaacttat
     5281 cctctctcca gaatacatca tattgagtaa tcataatcaa tccatctata gccataactt
     5341 cattaaaaca ttcatcaaag ttactaaatt cataaatatc catcttacct gtatgactat
     5401 catatacttt ccctactttt ttatcagaat cccaccaaat tccattcaca ggtatatcct
     5461 ttactccagc tacaccaatc attcctacat ctgcattttt tttaaatatc tctaaaatat
     5521 catatatgaa atttttatta attataaaag tatcttgatg taaatatacc ttatacttag
     5581 aatctgtttc tctcatagct ttattataag cagaggcaat agaatcggct cctcttaaag
     5641 ctactgtttc tatactaaag tttttaggaa tatctaggct atttatatat acaagacatt
     5701 cttcataaag tctttcatca tttacacagg ttataaaaca tatcttatca ttattcatat
     5761 ctcttcccct caataaaata aagtatctct tgtatgtcac tttcactctg tactttttcg
     5821 ctactatttt taattaaatt ataagcaata tcaaattctt ctaattcaca taatacactt
     5881 gttatattat atattgagtc aatatcatct ctatccatct ctaatacttt cataaacatg
     5941 tttatactaa aatctcctag acctctgtta aatgcctcaa ctcctaatct gtttaataga
     6001 gttactttat ttatcacaaa tgtatcaact aaatattcaa tatcatcaac aaaacatggt
     6061 tcagttatat tataattatc aaatatataa cttaaattac catctatatc caattcatta
     6121 tcaattctca ttaaagcgta ttttaaatta accatactaa tactagaata ttttttggta
     6181 tctatgcttt tagtggcttt cactatatat tgataagatt catactgttg tctcatttct
     6241 ttacagcttt ccttacacat tgtatcaata aatctattat cgatttccga aagcggcata
     6301 ctaatagctg taatactatt tattatgtaa ttactatcat taaacatttt cgttatctca
     6361 tttaatgtaa aaaaccttaa atgggtcttg tccagaatcc ctgaatcttc atatgtaaaa
     6421 ttacctaaca caagatttct taaaacagaa acatgcataa catttggtat actagatacc
     6481 aaataaccat ccttttttag atattgtttc aatttattga ctatcttcca tgggtcaatt
     6541 aaatgttcaa gtacatctcc caatattata taatcaaaaa aatttttttt ataatccaat
     6601 tttacttttt ctatatctgc tattagcacg tctgcactat attttgcaag tttaccagct
     6661 gactcactaa tttctattcc atatattgat gcatttttat atatattttt tatttctaaa
     6721 agagtagctc ctataccaca tccaatttct aaaacattga tatttgtctc tggactatca
     6781 tctattttag aaatcaaatc tgttcttata attccactat attctggatt aaatccccac
     6841 ttagtctcaa attttcttct attaatgtcc attatatctg tatatttatt gcgattttct
     6901 ttaaaagata tacttccaaa atggtgtata aaagtgtctt tgcataataa taacttatat
     6961 cctgactcta tcattctaaa agataaatca tcatcttcaa aatttccagg cgtgaatagt
     7021 tcatctaaaa ctcctacatt atctattaca gattttttta ttaacataca aaaaccaact
     7081 aacttcaatc tatatttcca tagattaata ttagatttat ttattttttg tgcaaatata
     7141 aacatctctt caactgattt gtagtcaaca tcaatctgtt gatagtatga acatgcattt
     7201 gttattggac ctacagctcc tatattatct tgtgaccata aagccttatt caaattataa
     7261 agccaatttg gagtaactat tacatcatta tttaacaaca atatattttc accattagcc
     7321 aactcaatac cttgattgca accttttgga aatcctaagt tcttgctatt atacacagat
     7381 tttatatcag attgtccctt taaccactca actgttccgt cagaagagtt attgtcaatt
     7441 attattattt catatttatc ctttggggta aatttcctaa tactttcaat gcataactta
     7501 gtatattcta tttgattgta tgtcaatatt attatgcttg taaattttat atcttcattt
     7561 gtatatgtat attgccaatc ttttattata tctttagatt tttcattaac caatattggt
     7621 gtattcattc ttcaattctc ccatttttga cttatcttaa actttttaaa tattctatat
     7681 tatatatagt gtcttcattt tctacatcta atgataatgc cttttttaac ataaagtcag
     7741 ctttgtcaag cttattttca aacatatata aaattccctt tatgtttaaa atctttacat
     7801 catccacaaa tgtttttgag tagtcatcta ccaataattt cgcatcattt attttgccag
     7861 tttcaatcat attttctata ctaataataa aactatcttt taaatcccta aactcttcac
     7921 tttcttttat attttcttct aattcaccta taagtatttt tattatttta ttataaaaag
     7981 gatactcatt tagtaatttc ctcatactat gtatatactc taatttttca ttagcactat
     8041 ttactttatt tttaatgtta agtagatgct taaattctat agtgaactta tctaaatcat
     8101 tacaaacaaa ttttattaat tcaaagtcac ttaaattgct atatatgtat cttatgtact
     8161 tataagaata cattatataa agataaaaaa tttccttata tttttcatca cttaagctta
     8221 tactttctaa aactacttta gatatagctt tatatactct tatcttttcc atatctgatg
     8281 tatttggaca actaattatg tacttatata gcgctaaatt aaaacttctt tctaatgcta
     8341 aaagatactt tagatatttc tctatccaga catattccat ttcataaaaa atatctagta
     8401 aatcaagctt ctcttcaaaa gctattttta taatatatgc ataaattatt tccttttctt
     8461 cattgagtat ttctttacat ttatctatag atacacattt atttatcctt atctgattta
     8521 aaatgccata attaccttca atgtcacaaa gaattttata tacatactct ttttcatctt
     8581 ctttaatatt atttataact tcttctatat ttctataaaa actatttttt tcaatttttg
     8641 aatttgaaac ttctttataa tagtttttta tatcttcaaa tctattcaat ttatataggg
     8701 acataaataa actaaagtac acattctttt tcttttctat atcttcaatg ttattatact
     8761 ctgaaattac agactcatat ctttcaagct tataataaat ctttataagt gtaataatag
     8821 cctcatccct aagccctaca gtatcagtgt ctgaaaacaa actatttgct tgtgtactta
     8881 tttcataatt atctaacaaa taaatgtatc tcttatacga atctatacta ttttcatact
     8941 tccctaaatc tacttgtgct tgtgcaatat aataatatat atcaatatta ttcatgtctt
     9001 tcttaatata ctttagacac aatttttcac acttcttatg ttttcctaaa tataaatatg
     9061 tttttacaag gcttgttatc aagtaaccag gtgccgattc tagtttagaa tataattcat
     9121 aagacttctc aagataatat aaagcctcct gatattttcc taatataata aaattttttc
     9181 ctaattgata atttgtatat ggagaattat cattctcttt taactcttca aataatagtt
     9241 tttcatttct ttttacttta tttaatctta tttcttcatc ttcaaacaaa tatccataat
     9301 gttcaaagtc agcaacatta ttaaatatag ggtttttgta tattggttgt tcatgtactt
     9361 taccatggta tctaaaatca acgtttttaa aaagtctaag cactgaacaa tatccatata
     9421 attttttatc atatgagtaa agatttttta attgtattga agcagaatta aattttttat
     9481 caagaccatc tttaaaaaat ttcacaatag ttgaagaatc aatcagtatt tcgtctgcat
     9541 ctaatataag taaccattcg cccttggcat aggatattga tatatttctc atactagaaa
     9601 aatcattatt ccaattatga aaatacactt tttctgtgta ctttttagat atttttatag
     9661 tatcatctgt agaacctgta tcaactatta taagttcact ctctatagaa tctcttaatg
     9721 tggttaatga ttttaaagtt ttttcaagta ttttttcttc atttttaaca atcataacta
     9781 tactaagcaa catatatatt ttcctttcaa aagtatattt ttaaaaaaag aaaggagtaa
     9841 agcaaagcct taccctttct tctatatcca atatacaaaa ttattttatc ctaataattg
     9901 taaaactcct tgtggttgct gattagcttg agcaagcatt gactgtgatg cttgaactaa
     9961 tatattcatt ttagataagt taaccatttc tgaagcaaca tctgtatctc ttattcttga
    10021 ttcagctgct gtaacatttt ctatagtatt atttaagttg ttttgagttg attctagtct
    10081 attttgttgt gcccctaatt ttgctcttga tgtatttaat tctttaagag ctacatctaa
    10141 actagatacc atttgtttgg ctgcatctgt tccagaagct ccatctacat ttaagcttgc
    10201 tattgtagaa cttgttatac ctgccttact cattatgctt gaagtattta ctagcgcaac
    10261 ttttatttca ttgttgttgt tagttgttcc tgcaacattt gttccaaaat tagctccaac
    10321 ttgtaatctt atttctgtag aacttccatc aagtaatttc ttaccattaa actcaattga
    10381 gcttgatatt ctttcaactt catcctttaa ttgtaacaac tcatcagcta tcttttgtct
    10441 ctcttcagca gtattagttt catttgaaga ttgtactgat aaagttctca ttctttgtag
    10501 tatattacca gtttcttcta atgcaccttc tgctgtttgt acaacagata taccatcttg
    10561 aacgtttctt cctgcttggt ctaaaccttt tatttgagct ctcattttct ctgatatagc
    10621 aagccccgca gcatcgtccg cagctctctt aattctaaca ccagaagaca gcttctccat
    10681 agacttactt tgtgcactta cgtttcttcc catttggtta tttgctatca aagcacttac
    10741 atttgtatta actctcatta ttttaccctc cttagtatag ttgacatcct tgtcatttct
    10801 actcttaact tttttattaa ttcttcattt atataatcgg acaagactat atataacttt
    10861 atactttttt attaaaaata tttacttttt ctctatttaa gctataatac attgtgttca
    10921 cttgtttagt aagcttatac tcatgtaatt ctttttttac ttctaataat tgtccttgta
    10981 aaatatctct tattctacta tcaatttcaa ttaattccat tttattataa agctgtataa
    11041 aatcatttct atcaatttca cttacactgt ttataatctc ttgtctttca tctaatttgc
    11101 tacttatctt tatatattct tccttttcaa tcaaatttat aatttgtaaa gagatatctt
    11161 tatataaatt taatttttct tttaatttat ccataattaa ttaccttgtg cttgtgagaa
    11221 ataattcatt tgggaagaat actgattcaa caaagattct aaagctgaat atttagcata
    11281 aagtcttttc tctttatcat tcattttttc aactaaccta cttatatttc tttcttgctc
    11341 tgcaatttgt tttgaataaa cattttcact agcagaagca gttttttcta tacctgcttt
    11401 tttaggaagt ttagaagttg aacttccaga atattcatat acaatatctt ttagcttttc
    11461 aaacattccc ttatcatcat aattcgaaga atagcctgct agtgatttgt ataccttatc
    11521 actatcatct ataagagcct ttgaaaaagt atctgcatta aacgatattt gacccttttt
    11581 attgtaattt tcgctttcat tgatacctag ttttcttaat gcaataatat tttttccatc
    11641 tccaaaaaat gcagattgaa tatcttcaac aaaacctctt agctcatcat catttctaag
    11701 tataccttct ttagctttct tttcccattt ttctatttct tcagttgtca tatcttcttt
    11761 ttgggcatct gtaagagggg gataatcctt tggtttttta gtagtaacta aaccatatac
    11821 cttgtccata agtttattat aatcatccac aaatgacttc atatttttaa cagcttcttc
    11881 agtatcagtt acagaagtta actttgcagt tccttttgaa tttacattat agtcaatatt
    11941 atctatatta aacgaattct gttctttact tatatgagtt actcttccat gttcatcagt
    12001 tacatcagct tctagatttt ttccatatac acttgccaat ttgtttccac cagcatcact
    12061 tacaaatgtg ataccattat cattagcaat ttgctgagct aaattgtcat ttccaattac
    12121 tcttaaatta atatctgatg atgaaccagt ctgttttctt gaaataatca attcacctgt
    12181 catctcacta taagaagcct ttatatcatt atctgcacaa agcgagttta tcttacttac
    12241 aatagtgctt gtagtatctt gttcagagat tggtatattt acatctccta tagttaaaga
    12301 actagctcca ctagcatttg gaggaaactg ttgaacaata ggttcacttg aatttaattt
    12361 gatagtaaat tttgctggtt cagccatttg agaaactgca aattgataat ttattttttc
    12421 tgcaccagct gagccttttg ctactataat actttcatca gaactagtta tttttgtaga
    12481 agagtatgct ttttgactta ctatactatt aggagaatct acacttagat atttatcata
    12541 aagatctttt gattcttgta taatatttct atatatttct tgcttccatt taacgatttg
    12601 ttgctcttgt tttgctttat caactttttc cttatctcta atcatactag cttctattat
    12661 gccttccata tcaaaatttc ctgaaagacc tgtaactctt ataggactta tacttgacat
    12721 ccctctatcc ctccatccaa ttatattttt attttattgt aaacttcatg ccatgtatct
    12781 ctaatttgtt ttactattgg caatatatca tcaattattt taatatcttt attttcatca
    12841 gctattgcta attcagattt tataaattca taaactttat acatatcctt tgcccattgc
    12901 cctgcatctt ggtctaatgt agtcattagt tctgtaaata tattttgaac tcttacaagt
    12961 tcattatgtg cttttaaata atcgttattt aaaagagcat ctttggatat gttagtatat
    13021 ttgactgtag catctacaag catcaatagt aattcttctt ttgataactt acctaattca
    13081 gctaaattta attccattat ttatacctac ttctttcctc tttacttttt ttatcagctt
    13141 catgccatgt atctttaatt tgttctatta caggcaacac attatctatt atctgaatgt
    13201 cttttctaat attagctctt gaaagttcat atcttacaaa atcataaact ttatacatat
    13261 cctttgccca ttgccctgca ttttggtcta atgtaaccat tagttctgta aatatatcct
    13321 gaactcttac aagctctcta tgtgctctct gcgtattttt atctaagata gctgctctgg
    13381 ctattttggt atattttact gctccatcaa caagcataag caataattgt tcctttgatg
    13441 ccataaaaac agcattttgt ttataagaat tataaggatt ttctccatac atatattact
    13501 tcctccaagc ttattatttt aatgacttta aaatatttat atttttattt gtagctttaa
    13561 tattctcact ctttactttt tcgtatattt cttttcttaa tatgcttata ttgttaggtg
    13621 ctgatatagc tagtttcaca ttgtttccat ctacccctac aatttttact tctatgtttt
    13681 ctcctataag tactgcttca tctttttttc ttgaaattac tagcatccac tatcacctct
    13741 caataatgga tgccttattg aatatttatc atcttgtaaa attatttgca ttccaaaatt
    13801 agtttttata tttatcacta taggagcttt catgtttaca gttgattctt caaacgtctg
    13861 accaagagta attatattaa atagcataac atcctttgga gattttactt ctagtttttc
    13921 tatggtttct tgatttaaaa ctatttcata ttcattaata atctcaaatg gcgatacaac
    13981 aacaaatcct ataccttctt cttcagtaga attaaattct tttaaagaat cattatcttc
    14041 tatatctaaa agctcatatt cttttaaatt ttcaaaccct aatatacctt tttttaatgt
    14101 aaccttcatc atatctgcgt tatttttact atatataatc taatatagat acactaaata
    14161 actttcctcc tgtttgtagt gaagcttgat aagttaactc tgctgccttt aattgaacaa
    14221 gcttttcacc atagtctatt tcttcatttt gtgacagaat ctcctttaac tgtatcaaac
    14281 tatcatcatt tttttccttc atagcctcta ctgtatttgc ttttgtccca tatatagacc
    14341 taacatttac tgtattttct attagttgtt ccatttcacc taaacaagtt gttgtgagct
    14401 cttttatagc atcagcatct ggatttgcta atttctttga tatattattt aactcttcaa
    14461 acgggtcagt ctttgttggg tcaaatccaa ggctactcaa tttaacatta tagtctacac
    14521 ttattccttg agctacgtcc atacttaaag aatcttttaa tttattaaga tctatactag
    14581 aattaaactt taagcttact gagccatcag cattatctac acactcaaca ggtggtatac
    14641 ctgtatttga acctgaaaat atgtacttac cttcatgtgt tgcatttaaa gcatttgcaa
    14701 tttcttttat tttttcattg gtttcattac taagggtctt tagttcgtca tctgaatatg
    14761 caccatcacc acttgccacc aaagttttct ttatgtccga taataatttc ccaagctgat
    14821 ctaatgcagt atcagtagtt tctaaccaat ttcctgtatc tttacaattc tcaacataaa
    14881 tctccatagt ttttatttca ctttttgagt ttaatatttt tattgcttta tatggattat
    14941 ccgatagctt gtttatttct ttggttgtat taacttgtct attaactttg tccaatcttt
    15001 gtagattatc ttgcagggag tttagataac tgctagacat catacctgta ctaactctca
    15061 ttataaattc ctccttctat taaattattc catttattac aacatccaac agttgcacag
    15121 ctgttgacat aacttttgca ctagcttgat aggaacgttg tatttttata agctctgtca
    15181 tttcttcatc caaagataca cctgaaacac tcattcttga attatcaata ttatttataa
    15241 ttttacgttg attcacttca tcttgattca cttttttaga atctaaacct actaattctg
    15301 caaaggcttt atagtggtca cttattgtac ttacttttcc accagccact ccaatatcta
    15361 ttttttcatc ctttaactta gcaatttttg aagcctcatc agcagtaagc tttaattcat
    15421 ttgggttact ctttatagct ggatttacct ttatgatatc ttcaccatct acatttgaag
    15481 ttacaaaaaa atctcttact gttattccag cagacgtatt atagacatca tttatctgtt
    15541 tagctaatcc atcagagacg tcttttaaat cgcttttata tgtatcaatc ttaccatgca
    15601 tttcaaataa tccttgtaag gttcctgata cacctgtttt ccaagttcca tctgcatttt
    15661 ttaattcatt aagttctaat ttaccatctg caagcatatt tttaacatcg ctattttcaa
    15721 aatctagctt aaagctcaag ttgtctaata ttctatctct ttcatcaagc aaatcatttg
    15781 gcatagagcc agaaccagag ataatatcaa tagatttatt caaatcttca agacttttta
    15841 acatttcatt gatttgtttt atctcagtat ctatattaga atctatatct ccttttaact
    15901 tgtcaagctt cttataactt tcgcttatta aggttgctaa attagatgca ttttctacta
    15961 ctagactttt tttactgtca ctatttatat cctttgataa cgactcccat cctttaaaaa
    16021 aatcatctat acctgcagat attccatagt ctgatggttc atttagtata gtttctatag
    16081 tattataata atcatatttt gaaactgtct taccatactt atgagcttct gctctaaatt
    16141 ggtaatcata aaaactattt ctagctcttg ttacatctgt tacatgtact ccagtaccta
    16201 attgtcctct tccaattgaa ttactcaaac taggcatata catagggcta tttgtagcaa
    16261 actcagtcct ttgcctagaa taaccttctg tgtctaggtt acttatatta tgagaaattg
    16321 tctgtattgc tttttgatgt gagttcattc ctgaattagc tgtatttaaa atggaaaata
    16381 atcctgccat atttctcctc ctaatattta ttttctaata tttccataag aattataagt
    16441 tgttgtttgc ttatcaactg gttttatgaa attaatcatt ttttttgtaa aaataagttc
    16501 tttctttatc agagaatcat ttgattcttg ttgattttta gctaaagcaa gaatgtgttt
    16561 taggtctgta tatatttctt ttaaatatcc atctttacta ttttcaacaa cctcactcat
    16621 tgaaatatca tcaccaaaaa gctgtcttct ctttatttct atggatgcaa gttccctact
    16681 aatatcttct agtttaggat ttaacatatt taaattttct aagtcttttt caactatata
    16741 atcaaattgt tcttttaata attccatcat cttactaatt atattttttt cttcatacat
    16801 tataactttt aagtctgtaa tcatgacttt atcctcgcat atcctctatc attttttttg
    16861 caatttcttt tggttttatt ttgtaagttc cattttctaa tgcatttttt atttcatcaa
    16921 cttttttatt cctaatactc tcatcactca tatttgatac acttgccatt tcctttgcaa
    16981 acttagatag ttctatctta tctgttttat taattttttt aacatcttcc acttttttta
    17041 caccagatgt attctttaaa taattattca ctacaatatt tgaacttaca tttttaatat
    17101 ccatagtttc acctccaaaa ttacatactt ataatttaat tatcgctcag aaaataaaaa
    17161 catttatata attcacacat attttaaact ttttataaaa atatcccctt agctaaactc
    17221 atacagagta gcctaaaggg atactattta aaatgctaat ttatatctga atcttctatt
    17281 ttagataatc ttacagataa cttctcattt gtaataatac tttctccata agcaaacaat
    17341 ctatcatttg catatatatc taatttttca tccacattct tatttagttt tattatagag
    17401 ccttctttta aatctaatat attttttatt gtttctgttg tatttcctat agaaacagct
    17461 acatttactt ttgcattaaa aacattttga ttttcttcta taataccaga ttgttcttct
    17521 attagttgcc caaaattcaa ttcatatata tcctcttttt tactattcat aaaacttttc
    17581 tccttgtata atcttatcta tacatatcta tcaacaaacc ttgtatcata tcaacagtag
    17641 aaacaatgtc tatgttttct ttttcttcac taattaactt actagtcata tcctcaagtt
    17701 tactgtcaac aatctttaca ttcttataat actgatgttc ccaaaaacta ctattcttat
    17761 caagtgaata catattatct acaacagatt ttaggtattc ttttactgca tttttatata
    17821 tactaatatc gccatagttt tgagtaagta caagcctttc tcctgccttt tttacactct
    17881 ctaaatttcg ttttatatct tctagtgaag aagattgttt taaagagttt aatctatcag
    17941 aaaatttatt attttctttt agttttttga cttctatatt tatacttgga cttattttta
    18001 gcttatctat atttataccc ataataaagc ctaccctcta taatatttca taaccttagg
    18061 aatataattt tgtgtttctt ttggcatttt atacaggtca gaaattgatt ccactcctct
    18121 actcttcatc cttccaggac caccattata tgccatcaac cccatttcta tacttcctcc
    18181 aaacatatca atatattcct taatatgtct agttccagca tctatattct gctctatatt
    18241 aaaagggtct gtaacaccca aatctctaca attttctggc ataagttgca taagaccctt
    18301 agcaccagca gaagaaacag tatttggatt aaagtccgat tcaactttaa ttattgcttt
    18361 tataagattc gcatctacat tatatttttt tgatgcttgt tctacagcat tttcaattct
    18421 caactttaca tttttatctt ttgtatcaac atctataaat ctactagtgg tattatttac
    18481 tacattctca agttcattaa acaaattctc agaattagac gatatattat agccattaga
    18541 agtatgttga ttattttgtg ataatgcttt taacaaggtc atcataatca tatcaaatcc
    18601 agatgaatta ttatatgtac aattacattg atttgtatta ttactaccag ataattgagt
    18661 caatgctaat atattaatta gtgaacttat ctcattcaat ataaaacccc ccttctaaat
    18721 tttataaatt tcaaagttac actgataaaa cagatttcca ccaagattca ttttctatgt
    18781 accacttaac agtttctttt ataccaaaat caaaatcata ttttgccttc caacctaact
    18841 cattctgtat tttagatgca tcaatagcat atcttaagtc atgaccaggt ctatcattta
    18901 cataggatat taaatcctca gatttaccta aaagatttaa tataattttt actactttta
    18961 gattacttct ttcattatga cctcctatat tgtaaatctc ccctatattc cctttatgta
    19021 ttattaagtc tatagcagta caatggtcat atacatgtaa ccagtctctt acattttccc
    19081 cattaccata tactggtaat tgtttatttt ccaaagcatt taaaatcata agaggtatta
    19141 atttttcagg aaaatgatat ggtccataat tgttggaaca tctagatata gttgtcaaca
    19201 atccatatgt tctataataa gaacttacca ataaatctgc tgatgcttta gaggctgaat
    19261 atggagagct tggatttata ggtgattgtt ctgtaaagaa taaatccttt ctatcaattg
    19321 gcaaatcacc atacacttca tctgtagaaa tctgatgata ccttttaacc ccatatttta
    19381 tagatgcatc taaaagtact tgtgttccta taatgtttgt ttttataaat aaatcaggat
    19441 tctcgactga cctatctaca tgagattcag cggcaaaatt aacaactata tcaaaccttt
    19501 cttcttcaaa tagcttatac atctgttccc tatttgaaat atctcctcta acaaatttat
    19561 aattggaatt gtcttgtatt tctattaatg tctctaaatt accagcataa gtcaacaagt
    19621 ctagattaac aataaaataa tctacatact tattaagcat ataatgtaca aaattgctcc
    19681 caataaatcc tgctcctcca gttatcagta tctttttcat attttttctc ctaaatgtta
    19741 attctaataa atttttatta acgtcttata cagatatctt taaaactttt ttgtttttta
    19801 tccttttctg ataaaaatat ttcttcaatt ccttttaaag gccactcaat agatatttgc
    19861 ttatcattcc atataaaacc attctcaaat tctggataat aatagtttgt acatttgtaa
    19921 ttaaatactg ctttttctga taaaactaaa aatccatgtg caaacccttc tggaatataa
    19981 aattgttttt tattcttatc agacagtatt acaccttccc attctccaaa tgtttttgaa
    20041 tcttttctta aatcaactgc aacatcgaaa acttctccct ctgtaactct gactaatttt
    20101 ccttgaggat atctaacctg aaaatgcatt cctcttaaaa ccccttttct tgaactagac
    20161 tcattatctt gaataaagca catatcaaga ccttgctcta taaaatccct tttattatag
    20221 ctttccataa agtatcctct ttcatcacaa aatacacttg gttcgactat atacaatcct
    20281 tctattttag tctttatgac attaattttt cccattataa caaactccct taataaaatt
    20341 tataataaat tttatctacc atattacata tcttcactag ctaactttaa tagatattga
    20401 ccatattcag tttttatcag tggcttggct agttccatta attgtgctct acttatatat
    20461 ccttttttat atgcaatctc ttctaaacat gctatatata atccctgtct tgtttgaacc
    20521 acttcaacat agttagaagc atccaataga cctttatgtg taccagtatc aagccaagcc
    20581 atacctcttc ctagaagttc tacttttaat tttcctcgtt ttagatactc actgtttata
    20641 gaggttattt ctaattcacc tctatctgat ggttcaacta gctttgctat ctctacaaca
    20701 tcattatcat aaaaatacaa tcctggtata gcataattag atttaggaac tgtaggtttt
    20761 tcttctattg acaatacatt aaaatcctta tcaaattcta caactccaaa cgaatttgga
    20821 ttacttacat gatacccaaa tatagttgct ccttttcttt taactgcttt ctccaatctt
    20881 tcactaaatc catatccata aaatatatta tcccctaata caagagacac tctgtcattt
    20941 cctataaatt cttctcctat tataaatgct tctgcaattc catttgcttt ctcctgaatt
    21001 gcatatgtta ttttaagacc taatgaactt ccatctccaa ataattcctc aaatgctttt
    21061 atatctcttg gtgtagatat tattaatata tcttgtatcc ctgccaacat aagaaccgac
    21121 atagggtaat atatcattgg tttatcatat attggaagtg tttgttttga tatacatttt
    21181 gttataggat atagtcttgt accagaccct cctgctaaaa taattccttt catctttttc
    21241 catccttaaa tttgtttttg tcatattatg attatcggat aaataaaaga aatatttata
    21301 ttttttataa tatcttattt tcttttctaa aaataataca tttactcttc attcatatca
    21361 tatctttcta aatattcttc aatggattct tcccaatttc taaaagaatt taaaccaatt
    21421 aacttcaaca taaaattatc caatacagaa tataatggtc tttgagcctt acatttaaat
    21481 tcgttactct taatcggatt tacttttatg tctatatttt ttaattcaaa tatctttttg
    21541 gcaaaatcat accaactaca ctcaccttca catgtagcat gataaactcc ataatgttct
    21601 gtttccatta ttcttattat aatttttgtt aaatctactg tgcttgttgg agttccaaac
    21661 tggtcattaa ctacattaac ctctttattt tctaaagaaa gttttatcat agtctttaca
    21721 aaattattcc cattaccata taaccatgct gttctcaata taaagtactt atgtgaaaat
    21781 tgttcaacaa acttttctcc cataagttta ctttttccat acacagaatt gggttcagtt
    21841 ttactgtctt ccctatatgg atatttagaa aaaccattga atacataatc agttgatatg
    21901 tgaataagtt tagcattaac tttttctgat gctattgcta gatttcttac tcctaaggca
    21961 tttactttat atgcagtttc tatattatct tcacatgcat caacctttgt atatgctgca
    22021 cagtttacaa ctacatcagg tttattattc aaaataaaat tatctacatt agtctgatta
    22081 tatatatcaa aatcattcct tgttgtagct aatatagcat atttgggttg actcatactt
    22141 tgattgattg cttctaattg gttaaccaat tcttttccta attgaccatt agaccctgtt
    22201 attaatattt tcattaatta tgttatcctc caataaatgt tcaattttac ttaataatta
    22261 attataacac agcttgcatt ttaacttagg ttgaacttat tatttcttat ataaataaaa
    22321 aagagatgta atattaaatg attatcatca tattattaca tctctttaaa tctaaatata
    22381 taaaatatat tgtaattacc aattaattat tagaaactta tctaaaatat ttaactccag
    22441 attcaaatat cttttggtct ttttcaccta taatgttctt aaatacttcc tcaccaattc
    22501 tctcagaatg tcccatctta ccaaacactc taccatcagc actagttata ccttcaacag
    22561 catagaatga accatttgga ttaaactcaa tattataagt agcttcatta ttaaaatcaa
    22621 catattgagt cgctacttgt ccattagcaa ttaattctct cataacatct tcactagcaa
    22681 caaatttacc ttctccatga gaaattgcta tattatgaat atctccaaca ttagtttgag
    22741 ctaaccaagg agatttatta gatgaaattc tagttctagc aatcttagct tgatgacgac
    22801 caatattatt gtaagtaagt gttggagcac tttcacttgg aactcttatt tctccatatg
    22861 gaactaatcc taatttaatt aatacttgga atccattaca gatacctaac attagtccat
    22921 ccttttgagt tagaaattca tttatggctt cttgaactct cggatttcta aatacagtag
    22981 ctataaattt accagaacca tctggctcat caccagcact aaatccacct ggtaacatta
    23041 ttatttgaga agattttatt tcatttacta ttgtatctat agaatcttct atatctttat
    23101 aagttaaatt cttaaatact cttatgtttg cattagctcc tgctctttca aatgctcttg
    23161 cagaatcata ttcacagttt gttccaggga atgctggtat gaatactctt ggagtagcta
    23221 tacttagtga tgatttttta gcttctcctt gtgatatata acttatagtc tctatctttg
    23281 attttacttc ttctgcttta gttgggaata taggctctaa agtactacaa tgtgatttat
    23341 ataattcatc taatgcaagt tcttcacctt tgataaatat actagcttct ttaactgtac
    23401 ttccaagcac aacataattg tatccttcta acatacttaa atcatcattt gctaattcaa
    23461 gtactatatt tccataacta gcctcaaata atttatcatc tttaaatgct ttttcagttt
    23521 cttcactaaa cttaaatcct attttattac caaaagccat tttacttatt gcttcaccta
    23581 cacctgcaaa tcctaatgca tatgttgata aaattttatt tccatgtata agctctctta
    23641 ctttgtctaa gtttctcttt aattcatcaa aatctataac atcattttct gccttgttta
    23701 cgcataacat tactactttt gaatctattt ttttaaattc tggagatact actttcttcg
    23761 catctactgt atcaacagca aatgaaacta atgttggtgg aacttcaata tctttaaatg
    23821 taccagacat actgtctttt ccacctatag caggtatctc aaatttactt tgtgcataaa
    23881 atgctcctaa aagtgctgag aatggtttac cccatttttc tggattgtta ccaagtttct
    23941 caaaatactc ttggaatgta agtcttgttg tactgtaatt tcctccaatg gcaaccaatt
    24001 tacacacaga ttctactact gcatacaaag caccatggaa tggactccat tttcctacct
    24061 ttggattgta tccataagtc attattgtag aagtattagt ttctcctcca agcactggta
    24121 tcttagcaac cataccttgc gttggagtag cttgatactt tcctccaaat ggcataagta
    24181 ctgtattacc accaattgta ttatcaaaca tctctactaa tcctttttga gagcaaacat
    24241 taaggtcaga caataccttt ataaatttgt ctttcatact tgcacactta acatctttta
    24301 ctatttcatt agagctaaag aatgtatttt cttcatctac tttagtaaca cggacatcag
    24361 tagtttgttt tactccattt gtgtccaaaa actctctatt tatatctaca attgcttttc
    24421 cattccagaa cattcttaaa tatcctgtat ctgttactgt agctacatgt gtagcttcta
    24481 agttttcttc tactgccaat tgtataaatt tatctttatt ttcttttttt atagctactg
    24541 ccatacgctc ttgtgactct gaaattgcaa gctcagttcc atcaagtcca tcgtattttt
    24601 taggcactaa gtctaagttt atatctaaac tatcagcaat ctctcctata gcaacacaaa
    24661 ctccacctgc tccaaaatca ttacatcttt ttatcatttg agcaacttct ttatttctaa
    24721 agaatctttg tatctttctt tcgttaggag catctccttt ttgaacttct gcactacaag
    24781 ttaagattga ttcttcacta tgctctttag atgaaccagt tgctcctcca cagccatctc
    24841 ttcctgtttt tcctccaaga agaactatta catctcctgc ttcaggtctt tctcttacta
    24901 cattttcctt tggtgctgct gctataactg cacctatttc cattctcttt gcaacaaagt
    24961 tttcatcata tacttctgca acttgtccag ttgtaagacc tatttggtta ccatatgaac
    25021 tatatccatg agcagcttct gtcgttattt ttctttgcat aagttttcca ggtaaagtgt
    25081 cctctaaagt tgttcttggg tcagcacttc ctgtaacacg cattgcttga taaacataac
    25141 ttcttcctga taacgggtct cttatagctc cacctaaaca agtagctgct ccaccaaatg
    25201 gttctatttc agttggatgg ttgtgagttt catttttaaa cattactaaa tacttttcca
    25261 tcttaccatc aacttcaaca tctacattta tactacaagc atttatttct tcactttcat
    25321 ctaggtcatt taatttccca tttttcttta attcttttac tgcaacagta gctatatcca
    25381 ttaaacatat atctttatgt ctgttcacat atacattgtc tcttgagtta agatacattt
    25441 gatatgcttc ttttactata tcattaaact taccatcttc tatctttaca ttttctattt
    25501 cagtcataaa agtagtatgt ctacaatgat cagaccaata agtatctaga acttttattt
    25561 ctgttatagt tgggtttctc ttttctgtat ccttaaagta tttttgaacg tgttgtaagt
    25621 ctcctaaagt cattgctaat cctttttcac ttacaaatgt tcttaatcca tcttcatcta
    25681 aatctataaa tccatctaat acttcaactg ttgttggtat ttcagtttcc atttttaatg
    25741 tttctggttt ttctaaagat gcttctctac tatctactgg atttatacag taatctttta
    25801 ttttagaaaa ctcttcgtca gttattttac ctgataatat ataaactttt gctgtattaa
    25861 tagcaggtct tatcccttga tttacaattt gtacacattg agctgcccaa tcacctcttt
    25921 ggtcatattg accaggaaga aattctattg caaatactct ttcatcattt aattttggta
    25981 tttcttcata atatactaca tctagatttg gttcagagaa tattgtcttt gctgcatttt
    26041 cataaacttc ttctgatatt ccttctacat catatctatt taatattctt aaattttcta
    26101 tattatctat gtgtaaactt tccaccaagt ctttttttaa agctttagcc tcaaggtcaa
    26161 aaccttctct tttttcaact agtactcttc taaccattga gtctttattt tcagtattca
    26221 acatacctta tcctccattt tagaaaaatt atcttcctat gtctgttcta tagtgcattc
    26281 cttcaaagtt tatcttcttt atattttcat aaactttttc tgctgcatct ttaactgtag
    26341 ctgactttgc agttatacca attactcttc ctccattggt aactaaatta ccatcaagca
    26401 tcttagtgcc gctatggaat actactatat catcatccaa gttttcaaga ccagttataa
    26461 ttttcccttt ttcataactg tctggatatc ctcctgatgt aagcataaca catacagctt
    26521 catcatcact ataatttatt tctatatctt ttaacttatt atctagtata gattccatta
    26581 tctcatgtaa atctgtttct aatctaaata aaacagattg tgtctcagga tccccaaatc
    26641 ttacattata ttcaagtact ttctctccat cttcagttat cataagacca acaaataaaa
    26701 tacctttaaa atcaagtcca tcttttttga aaccttctaa agttttttct aatactgtct
    26761 cttttactct atttgctaat tcttctgtat atatttcact aggtgaaaaa gttcccattc
    26821 ccccagtgtt tggcccttgt tcatagttgt ttactttctt atggtccttc gcacttgcca
    26881 taggaactat tgtatcatta tctacaaatg ctagaattga agtttctatt ccttttaaaa
    26941 actcttcaat tactatttta tctccagcag ctccaaactt cttatctgac atcatttctt
    27001 ttaaagttgc tatagcatct tctctatttt caggtattac aacacctttt ccagcagcca
    27061 atccgtccgc ttttattact actggatatc caaagttatc tatttctgat atagcttctt
    27121 ctaagtttgt atattcttta tattttgcag taggtatgtt atgttttatc ataaattctt
    27181 ttgaaaaagc tttgcttcct tcaagttgag cacatttttt attaggtcca aatactctta
    27241 atccttcttt ttcaaactca tctactattc ccataactag tggtacttct ggtcctacta
    27301 ttgtcagacc tatttcattt tctttggcaa attttaaaag ttcttctata ttagtatcac
    27361 ctatatttac gcattctgct acatttgcaa ttcctgcatt acctggtgca caataaattt
    27421 tttctacatt cttttctttg cttagtttcc agcatatagc atgctctcta ccgccaccgc
    27481 ctacaaccaa tatcttcata atatcctcct tagtgtttga agtgtcttat tcctgtaaat
    27541 accataacca tatcatactt atcacaagct tctattgaat ctttatcttt tatagaacca
    27601 cctggttgaa ctactgctga tattccatat tcatgagcta atgttacaca atcatcaaat
    27661 gggaaaaacg catctgacgc taaaacagct cctgtaaaat ctttatcttt gttattttca
    27721 agagcatttt ttaatgccca aattcttgag gtttgtccac aacctaaagc tagagtttgt
    27781 ccatttttta ctattgcaat tgcatttgat ttcatatttt ttactactct cataccaaat
    27841 tccatgtcct taagctgtgc atctgttggt tttgcctttg ttacattttc acttttttct
    27901 gctaatatat tatttctatc ttgtatcaat aattttccat ctaaatattt catttcatat
    27961 ggttgtaaac tattttctat tttagctaat tttaatattc ttagattttt cttttgctta
    28021 agtatctcta aagcttctgg ttcaaaatca tatgccacta ctatttctaa gaatatttca
    28081 tttaatttct ctgctgtagc tttgtctata gtagaagtta ttcctactat tccaccaaat
    28141 attgaaacct tatccgcttc ataacatttt gtatatgctt caaaggcatc ttttcctaga
    28201 cctaccccac atgaattagc atgttttata gctactgaaa ctacttcttc gctatcttta
    28261 aattctctca ttacttctaa acatccatgt aagtcattta agttgttaaa agaaagttct
    28321 ttaccgccta attgctcata atttaagatt ggattttttg catttgattg tgaatataag
    28381 aaaccatttt gatgtggatt ttctccatat cttaaagttt gttctttttg gaaagttaaa
    28441 tttaatatgt cagggtacgt atctccaact tctccagcaa aataactaga tattaacgcg
    28501 tcatatcttc ctgtagttga gaaagcttta tatgataatt tttttctgtc ttctaatgtc
    28561 attgtatctg tttttaattt ttctattata gaatcataat cttttatatc tactactact
    28621 attacatctt tatagttttt ggcagcagaa cgtatcatag atggaccacc aatatctata
    28681 ttttcgatta tttcatcatg actttttcca gcttttaaag ttccttcaaa atcatataga
    28741 tttacagcta ctaaatctat tgaatgtatt ttatgttcat ttacagtttc tacatgagat
    28801 tctttatctc ttttataaag tataccacca tgtatatatg gatttaatgt ttttactctt
    28861 ccatctaata tttctggaaa atttgtaaca tcttcaactt gcattacatt aacaccattt
    28921 tcttttaatg ttttaaatgt atttcctgta gatataattt cataatctaa cttatttaac
    28981 tctttagcaa attccactac accagtcttg tcagttacac ttattaaagc tctcttactc
    29041 atttataaac actctcctac cttgaagttt taatttattt tcacaaaaaa gacttatact
    29101 ttcttttaaa atcctatgtt caacttctaa cactcttttt gcaagtgtct ttgcatcatc
    29161 atcttgattt accttaacta catcttgcat tatgattggt ccagtatcag caccttcatc
    29221 aacaaaatga actgtagcac cagttacttt agctccgtaa tcgataacac cttgatgaac
    29281 tttttctcca tagaatccag ctccacaaaa tgaaggaatt aatgatggat gtatgtttat
    29341 cattttgttt ctaaactcat taaccagctt tgggctgatt atttttaaat aaccagccaa
    29401 aactactaaa tctattttat tttccttaag aatttctatt atcttgtctt catcagtttc
    29461 acaaattgct tttatgttat gatttttagc tctctctagt ccataagcat cttgcttact
    29521 tgaaataact actttaacct gaccttttat ttctccagac tcagtgccat ctataactgc
    29581 ttgtaaattt gttcctccac cagatattaa aactcctata tttagcataa ctctacacct
    29641 tcatgactat ctactacttc accaattata tacgctttat cttctaataa ttcactgtat
    29701 tttttatcta cataagcagc attgtcattt tctctattat ttataaagtt tacaacatca
    29761 tcagcatttg ctttatctac tattaaaact agcccaatgc ccatgttaaa acttttatga
    29821 agttctctct cattaacagc attaaaacct tctatcattt taaatatagg aggcttctcc
    29881 cacgattttt tattgatatc tagtcctaag cctttaggta taactcttgt tatattttct
    29941 ataagtcctc caccagttat gtgagctatg gcttttattt catgtttagc taatacatct
    30001 aaagccaatt taacatatat tttagttggt gttaaaagtg cttctccaac tgtcattcct
    30061 agttcttcaa catattgttc cattttataa ttgtaagttt ctaaaaatat ctttcttata
    30121 aaagaaaatc cattactgtg tactccactt gaagatatac caaccaatac atctcctgac
    30181 ttaacattat ttccagaaac aatcttttct ttgtctgcta ttcctacaga aaatcctgct
    30241 aaatcataat catcttctcc atacattcca ggcatttcag cagtttctcc accaattaat
    30301 gcacaaccag acattttaca accgtctgca attccaccaa ctattttttc aatatgctca
    30361 ggaactaatt tcccaagagc tatatagtca aggaagaata atggttttgc tccttgacaa
    30421 attaaatcat tcacacacat tgcaactaaa tctattccaa cagtatcatg cttgtccatc
    30481 atttgagcta tttttaactt agttccaaca ccatctgtag atgcaagcaa aactggctct
    30541 ttcataccta caaaatcttt taaactgtat aatccgctga aattacctaa atctccaact
    30601 acatttccat cataagttcc ttttatttta ccttttataa ggtctactgc tctatttcct
    30661 tcatctatat ctacacctga ttctttataa gttaacatga aagtagttcc tccttatcaa
    30721 ttttcttaac tgggtattct ccatcaaaac aagctttaca gaaagtagac ttgtgttctg
    30781 ttgcatctaa cattccttct atatctagga attttaaact atcacatcca atgtattctc
    30841 tcatttcttc tacgttgtta cttgatgcaa ttaatttaga gcgatttgga gtatctattc
    30901 catagtaaca agaataagct actggaggag aagttattct aagatgaatt tcttttgctc
    30961 ctgcttctct taaagatttt actaattgtt tagatgtagt tcctcttaca attgagtcgt
    31021 ctactaaaat tatagacttt ccttttatta ttgttgaaag aggatttaat tttattttta
    31081 ctgctatttc tctttcttct tgtgtaggtt ttatgaatgt tcttcctaca tatctatttt
    31141 taactaagcc ttcacttatt tttaatccac tagcatttgc ataaccaata gctcctggcc
    31201 aacctgaatc tggaactgga actaccatat cagcttttac agtttcattc tgagctaatc
    31261 tttcaccaca tttaattcta aattcatatg catttacatt gtctatagtt gcatcatttc
    31321 ttgcaaagta tatgtgttca aatatacaac ttttcttaac tggtttataa ttttctgaat
    31381 aaaaatatga ttttagttct ccatctttaa ctactattat ctctcctggc tctacatctc
    31441 ttataacttc tccgccaagt atatctattg cacaattttc tgatgcaaat atatattcat
    31501 cacccttttt accaagtaca agaggtctga atccatgtgg gtctctaact gcaaccaatt
    31561 cttcttgact cattattaca agggcatatg caccttttat ataatccatt gtcactttta
    31621 aactttctac tatatcccct ttgtaatatc tcgcaagtat atataaaatc acttctgtat
    31681 ctgaattagt ttggaacata tatccatctt cttctagcat atcttttaaa taatttgcat
    31741 taactagatt tccattatga gctatggcta attgtctttt tctacaactt ccaactaaag
    31801 gttgacagtt agaaacatga cttcctccag ctgttgaata tctaacatgt ccaatcccta
    31861 tatttccttt taacttagat aattcacttt ccttaaaaac atctccaact aatcccatat
    31921 ctttcttgta cttaatttct ccatcatcta aaagagctaa accacagctt tcttgccctc
    31981 tgtgttgcat agaatataaa gaataatata gttctttagt tacatcttta ttagagtaaa
    32041 tccctaaaac tccacacata catttgcctc ctatttatta ttcattcttg aaagtacttc
    32101 cgtataacct tctacaaggt ctccaaggtc ttttctaaat ctgtccttat ctaacttttc
    32161 atttgtgttt acatcccaaa gtctacaagt gtctggtgat acttcatctg ccaatattat
    32221 atttccttca gaatccttac caaattctat tttaaagtca actaacttta ggtttaattt
    32281 taagaaaaat gcttttagta actcgtttat ttttaaagtt tcttctctta agaactttaa
    32341 ttcttctcta gttgctaact tcattgctac tgcataatca tcatttaaca ttgggtcacc
    32401 ataagcatca tttttgtagc ttatctcaaa aattggctcg tcgaaaacta caccttcttc
    32461 aagaccaact cttttacaaa tagaacccgc agcaatattt cttactatta cttctaatgg
    32521 taaaatctct acttttttaa ctaacatttc tctatctgat aaactcttta taaagtgagt
    32581 atttatatta ttttctttta acatttcaaa gattattgtt gatatcttat tatttagtat
    32641 accttttgaa gatatttctg cttttttttc tccattaaat gctgttgcat catctttata
    32701 ataaacaaca tattcatttt cattatctgt agaatatact tgttttgctt ttccttcata
    32761 taataacatc tctgctaccc ccttaaattc ttgtcgtctt ctaacacctt ttgtgccatc
    32821 tcttctctat atgatttcaa atcctctttt aattttgggt attttaaagt cattatttgt
    32881 aatgccaata aagctgcgtt taaacctaag tctattgtaa ctgttgcaac tggtattcct
    32941 tttggcattt gaactattga taaaagtgag tctagtccat ccatagttga tgatttaata
    33001 ggtaatccta ttacaggaat taatgtttgt gaagctatta cacctggtaa gtgtgctgct
    33061 tttcctgctg ctgctattat tacatcagta tcatcttcta tttcttttag gaatgttgaa
    33121 agttgttctg gtgttctatg agctgatagt gctcttgcta caacttctat tccatatttt
    33181 tcaagcagtt ttatcccttc ttctaacttt ggataatctg attttgaacc cataactact
    33241 gctactttca ttagacttcc cctctccgtt tataagttat tttacactat aaatcattcg
    33301 tatgattata cgaattatac accttaaatt ttatattaat atacatatat tatcaactct
    33361 tttttgaaat ttttaaaaaa aaatatttct tgtatttttt tattcgtcac gtatcgaact
    33421 ttatttatgt ttttttatta aaataaaaaa cagattatct caaaattgat ttttctaatc
    33481 agattttaaa cttaatctcc tttttaaaat tttgtatatt attttttatt acttattttt
    33541 taattaatat cttaaattta tagtcttgtt ttttaactct gaatgttact ttcgcttgga
    33601 taaaactaat acatagttta ttctttatct aagtaatagc taaaacttaa agtgatgata
    33661 ttatatagat agatataatt ttatttaaag gagaatctgt atgttagaag ttataaaaaa
    33721 tagacgttca ataagagcat atataaataa aagcgtagaa gaagagaaaa taactgaaat
    33781 actaaaatca gctatgcaag caccttcatc aaaaaatgct caaccatggg aatttatcat
    33841 agtagatgat aaggaactac taaaaaaact ctcaaaatca caacatagag caaagcatat
    33901 agaatttgca ccattatgta tagtagtgct tggaaataga gataaattct taaaacctgg
    33961 taaatggata caagatttag gtgcttgcac acaaaattta ttattagagg ttactaacca
    34021 aggtctagct gcttgttggg taggagtatt tcctaaaaat aaagtggtaa ataaagttag
    34081 acaaacttta gacttaccag taaaattagt accttattca cttatatcta ttggatatag
    34141 tgaagaaaaa aatgaattta tagaccgatt tgatgaaaat aaaatacata gaaatatata
    34201 taaaaataga tagtgtttta tttcctctaa actagctggg acataaaaat ctcctatata
    34261 tactagtgct atattagggg atttttcttt gttttgtaat tgatattaaa aacaagactt
    34321 aagaccttgg ttttattttt aaaattcatt ttatctaact ataaaattta agatatagaa
    34381 agtacagcag ttaattattt taaatttgtt gagaatatct taaaattagc cattttcctt
    34441 aaaatatttt agtaaattaa tacttcctat caaaacttca gtaaaaatat accacttaat
    34501 tattattaag attaatcttt gtacaaaaat tcatattgcc tcttaaaaga gtacatacaa
    34561 ataaatttta tctaattggc atttaaataa actatcttac aagtatttaa tagtaactct
    34621 cctacaaaat tttattagta tatgagttaa ctaaatttta atataaagag aacataaaat
    34681 actgtaaaaa agtgttatgg ttatttcgtt gaaaagaaag acatactatt aaagcataaa
    34741 ttaaaatata ggagatgatt aaatgagaat actttcagaa actgaaaaaa tatccttagc
    34801 agcagttata aaaatggaat ctgatggatt acttatgcaa agagcaataa atatgttaat
    34861 atcagatgaa gacctaaaaa gacaatcaga atctagtata ttagcaacag aaggaagaat
    34921 taaagctata caacaattta tagttgaaaa tgaaatacta atttctgagg aggtatagat
    34981 aatatgagaa atatgataga aaatctaatt aagaacaata cttatataga cgataaagta
    35041 ataatgttaa gtatgctttc atctgctaaa gcatctgcca atatgtatct taattctgca
    35101 ttaacaagta gtacacctga attaagagct atatattcag cttcactaac tcaaatggtc
    35161 gaaggtcata cagcacttac agaattaagt attaataaag gatggtttaa accatatgat
    35221 aaacctattc aacagttaac atgcagttat aaagaatccc aaaatgttat tgactaaact
    35281 aaataaaaca tatttctaac tatttcactt taattaaata ataaaaaggg gatattcaaa
    35341 ttttttaaga tttccccttc ttctaaataa tctatttttt aatataaaat agattgctta
    35401 caatctaaag atataatttt atatagttat tattaattat tttagacaat tctatttatt
    35461 aacatttttt actacatatt tttataaaca aagacatcaa atccttatgt tccaaaatta
    35521 aaaaatcagg cttataaaac accccttcta cttcatgtct cctatggttc aaccatatac
    35581 tcttccaacc agctttttta gctcctaata catcatttct ataagaatca cccatataat
    35641 atgtattttc tctatctaaa ttcataacat tctcagctac tctaaaaata ttagtatctg
    35701 gcttagaaaa tccaacctca ctagatataa aaatattatt tttatcaacc cagttttcaa
    35761 tatttaactg ctttaacttc attctttgat gagttgatgg accattagtt ataattccta
    35821 gattaatatt cctttcttta gaaaaattta aaacccactc aacttctggt attagtgtaa
    35881 tttgtgattg ttggtatata tactcatctt gaaaactttg tgcatctttt tctgtaatgg
    35941 aagttcccaa ttcctcaaaa gctttcatta ttctataaat atgcatttct ttgattgcca
    36001 tttctccatt ctcagtcata tgaaatacct catcactata ttttctacta ctcatatata
    36061 agtcttcaat agaaatattc tttattgaag aaaacacttt attatatgca atataaaaag
    36121 gtgttaattg attatataaa gtatcatcta catcaaaaat taaattaatc aaaatattag
    36181 tcctcctaaa tttaatagtg gtaagtataa ttataactat aaatacctag tataacaata
    36241 ctcaccacta taagtcccat tatttattta aaatccttgt agtaacacct tttaagttat
    36301 aacattccgc ataatcacgt aaaggacgtt taatgtggtc tataacaaat ctttgaccat
    36361 caatattatt cttacttaaa ttagcataaa gcacttctat ttcttttttg acatcatcat
    36421 tattaaatgt ataatgccct gcaatatcta atatttcatt agataaaact tcattcttaa
    36481 atatatcttc agtagttaga tttttttgtt ctcctattac ccattttctc caacgtccac
    36541 attcaattgc attaacaaga agaacatgtc tgatattaga agttttatca actaaaccct
    36601 ctttttctaa tttacactca acttctgcta attttaaata tgctctagtt tcttcagtac
    36661 catattgagg agctacattt gtagcaataa tactagatgg tatatgttct aataaagtta
    36721 catcatctaa gtaatcacca ttatgctctt ttaaaccaac tccatatttc ttagccattt
    36781 gagctaaatc ataagcattt ctaaaattaa aagttcctac ttgttctgtc tttctagtta
    36841 aagtaccagt ttgaccaact ataaatgttg gcattggcaa acctctctta tcaagttcaa
    36901 cttttagtct agttataaat gtttcatacg tctcagttga agtcagacct ccattggttt
    36961 cctctgtacc aacttcataa cctatttctg gtagattgag tctttttctc tcattttcac
    37021 aatattcaat taattctaca gttctttcta gtactacatc tagtggaatt acttttccaa
    37081 tttcaaatgg gtcttttgta gggtcaatca ttaataggtc aaaacctgct tcaatgtccg
    37141 ctaaataaga tttttttcct aactccattg cctcatcaac aggtaaatgg tcatttctct
    37201 ccttatctct ttgccatggt ccaccatggt ctctacataa ataatataaa ccatcaaatc
    37261 caactttatc ggcaatcttc ttaatatctt ttgtaaaagt ttcttgattc caaccattta
    37321 catagccgcc acctagttca tctgcatcta cttgatttct gctcgcaata aacattaaag
    37381 gaaaatcatc atcttttgct aattcaaaac ttgcttgtaa caagtttggt gacataggac
    37441 caattcctaa aagagttgca cttttcccct cttcttgtaa ttctagtaat ctttgtacga
    37501 cagtctttat tggtaacttt ttcatgacta tatctccttt tattctattt ttaagatatt
    37561 ttcaaagatg tttttaataa aaatctcctt aaaaacatct ttgagttata tgtaaaacaa
    37621 atcaattttt attgaaaagt atcttttatt ttcttaatta atgcatcaga tttcttaatt
    37681 atgtcagata cactcattct tactactttc tttcccttaa aacgttccat atttctaatc
    37741 tcaacatcat tagtcaatat tacacaagtt gcttcctcaa tctctttaag cgacaattca
    37801 ttatctatcc cagagcttcc ttgagtttca acctttattt ctatgccaaa ctttttggct
    37861 gataattcaa gtgattcagc tgacatgtaa gtatgtgcta ctccactagg acaagatgtt
    37921 actgctacaa ttttcatatt cttatctcct ttagacttat atttttatat atttactttt
    37981 ttatacaaat tcctttctta tttatattta taattcttca aatattaatt caatcgagtc
    38041 atctaaatcc tcttcaattt cttcatcttc tttcacgtct ttttttacta atttcattaa
    38101 tattgcaaca actactgctc cagttaatac tgatgcaata taccccaacc tattgtcaac
    38161 tacgggtaat actatcagac ctccccaggg tgcatgattt aaacatccta ataaaaaagc
    38221 cataatgttt cctataatcg acccaaccat aatacaaggt attactctaa cagggtctga
    38281 tgttgcaaat ggaatagctc cttctgtaat tccaacacat cccattaata gtgaagcttt
    38341 tcctgaatct ctttcttcct tgctaaattt ttttggaaac aataatgtag ctaatcctaa
    38401 accaattgga ggtatacaaa ttgcaacacc aactcccccc attaaatatg gaagtgtgtc
    38461 aacttgagtt tgagcaaaag tagctgcaac cttatttata ggaccaccca tatctgaagc
    38521 tatcattcct cctaaaattc ctcctaaagg aattttagaa acaccagaca ttccatttaa
    38581 ccaattagtc atccatgtca taaaagaagc tataggttct ccaattaaaa atacaattat
    38641 accacctgta atcaatgtac caatcaaagg ataaataaat atcgaaccta aagtcctcat
    38701 tgtaggagct aatttaattt tctttaattg taaaacaaca aatcctgcta taaatcctgc
    38761 tatgatacca cctataaaac ctgcatttac ttcttttgct aaatatgcac ctatcatacc
    38821 tggagctaat cctggtttat ctgccatact aaatgctata tatccaccta atataggaat
    38881 gaataaggcc aagccggcag ctccaatttg attcagttta gccaaccatc ctgtttcagg
    38941 aacagcagct tgtccactta gagttactga taaagcaaat aatattcctc ctgcaactac
    39001 aaatggaatc atataagatg ttgctgtcat aagatgtttt tgcaaaaact ttaaaattct
    39061 cattttaatc ttccccctct attttttctt ttataagatt ataaacagtt tgttcatctg
    39121 aacatctaat ttgatttcta aaactttcat gcatcaataa acgtgctaat ttcgataaaa
    39181 tctttaaatg aagattattt tcattgtctt ttgttactga tattaaaaat attaaatcca
    39241 ctttttctcc ttcttctgtc cattcaatag gagtatcaag ttttcctata gtaatacaag
    39301 agtttttaac acccacactt tgactatgag gaagacctat accatgtcca atataagttg
    39361 acaatgtttc ttctctcttt aaaacatcct ctaaaaattg atttttatct cttaaatatc
    39421 cttcttttga tactacatca actaatgata taatggcttc ttcttttgaa ttagcatgta
    39481 ttttaaatga acattttaca ttaactaatt tactcataca gttacctcct tctcatattt
    39541 atgaattaaa ccttctgctt cttcctttgt ctttgcactt tctaacatag aaataaaatt
    39601 agtcttataa accattttag ttagattaat tattgcagga atttgctctt ttttatcttt
    39661 gcttgctaaa caaaatatga ttctaacctt tttatctcca aaactaactg cttctttaca
    39721 tattaataga cttatcgaac ttactttgac taatgaacta tcattaccat gtagtaaagc
    39781 aaattcgtta tcttttacag cataaaaacc cacatttttt aaaatatcta taatattttc
    39841 agcatattgt gatgatacaa aatcacaatt agcaagtata tttgaactaa tttttacagc
    39901 atcttcccat ttcatatctt catcaattat ccttatggta tcaattccta ttaaatcgcc
    39961 taaattaagt tgtctagata atgctctctc atcactgtat ccaagttctt gacatataac
    40021 acttaatact cttttttgag catcttcttc taaaaagtcc aacctttttt ttattgacat
    40081 ataattagtt aagacgttct ttctttttat acctttttcc tcaaacttca aataatcctc
    40141 ttcttgtaaa aatggattta tctcaataat tgttttaggc aagtctatta ctatctttga
    40201 tgttgttata atgaagtcaa tactttccca gtctttataa tcttgtaact tatatgatgg
    40261 aatactgtcc actatattta tctggtaatc atttattaga ctatctttta acatagcaat
    40321 tacaccatag ccaaatccac aaactaacaa tatatttttg tagttattcc tctcatttct
    40381 atgtatactt cctaaaaaat gtattgccaa aagtattgtt tcattttcat tctttatttg
    40441 atttaaaact ctgttctttt gaatagaaac cttagtagct tcaagtacat attggtactt
    40501 atctggtatt acatgaagta attcttcata aatctgtatg ttctgtttga ttctctctat
    40561 caatggggca atatgattta gtaatccttt ataaagaatc atatcttctt taaaactaat
    40621 ctctaatatt tctgacatat tgtaaattaa atcttgaact ataatctctg tactaatcag
    40681 atccatatcc tcatttaagc ttgcatattt atttgtaaaa aatacaaaac tctttaacag
    40741 aaaaatttgt tccttagtca actttttttg aataattgtt tcaaactctt ggtcaaactt
    40801 attttcaaaa catggctcac ttaatgaaac agattctaaa ggatgttttt catctgaatg
    40861 tatataccat gtaaaaagga aaatgtttga cacataccat gtgaaagatt catcatttaa
    40921 agtccatccc atttgcaata ataaattcat agaccaatta tatatatcaa tcaaagaaat
    40981 ccccttgaat attttttcaa tcacattcac taaatacttc tcaaatacac ttaaatcaga
    41041 tttttcttta ccaaaaagat aagaatatga ttttaatata ttcaatcttt gcttatatat
    41101 aatgtcttct tctccactta ttttaaaagc tttatcataa gtaatagtta tttgatttct
    41161 ttctaattca cttgataaaa cattaaggtc atttttaatt gaacttctag aaacctgaaa
    41221 ttctttactc aatttttcta agtttagatt ctctatttta aacattgata taattttcat
    41281 aatagatact cgctcagtta aggaaaatac atattcgtta ttatttatac atactacttg
    41341 gaagttatca ggaataatta acacaccttt gttcatcttt tgtattactg gcttgtttaa
    41401 tgaacgcaaa acaatattta aattatttat atcatatcta acttttcttt cttctatgct
    41461 aagttgtttg ctaatatcct tgtaacttgt cttatttttt ccttttagaa aattcatgat
    41521 gagtaacatt ctcccactta tcatattttc cctccttcca aaataattag agttattaat
    41581 atagcaaatt ttacattgtt atgtatgttt tagttttttt atctaaaaca gtaactatct
    41641 ttctatattc agaataatac aataaagctt tagccacaac ttacaacatt tgaaaattat
    41701 ttttacaaaa tctgcaaata cattttttat taaatatata aataaaaaag gcaagttatg
    41761 ttttaattat ataacttgcc taaatttttt atcttatcca tttaataatc agatattttt
    41821 aattttatta ttttcatatg caaaatcttc aaagtcagaa attagtagtg gtttagaaaa
    41881 aacataacct tgaatatagt cacatcccac attttttaag aactcaactt gctctaattc
    41941 ttcaattcct tcagcagtta ctttcatacc tagccttttg ctaagttcaa taatagactt
    42001 aataactacc ttaccacggt ctatattatt tttgctgaca aagaacgaac ggtctaactt
    42061 aattatatca actttaaaat cctttaatat tcctaatgat gaatatccaa atccaaaatc
    42121 gtctatagaa catttaaatc cattagaatg aatatcatct attatatcta cagcttctgg
    42181 attttctaag aaaatagatt cggtaagttc taaatctatc agatatgttg gtacattgta
    42241 tttattgcat ataagcttat atttttctaa aaacaattta tcattcaaat gttgacgtga
    42301 tacattaaca gaaattctca atacttcttt accttctttt atccatttag aaatcaattt
    42361 gcatgtttct tcaagtatat acaaatctaa cttacatata aatccacttt tttcaaaaag
    42421 aggaataaaa tcacttggat aaattatgcc tttttccgaa tttttccaac gcacaagaga
    42481 ctctgcacca ctaatttttc cactttttat atcaatttta ggttgtaaac acataaaaaa
    42541 ttctttattt tcaagggctt tttccattaa atttgaaatt tccttttcag atattaatcg
    42601 ttttctttct atatcactat aaaaagaaaa atcactttga tgagctttat taaagctttt
    42661 tcttgctgta tttgcatggt cttgtatcgt aattaaatct tcattatgat tttcaattgt
    42721 gtaaatacct gccgatattc ttaaaaagta tggattttct ctatttttat taaaataatt
    42781 tatatcagct tctattttat ataataactc caaggcttct agcactggtc tattcttaat
    42841 aagcaaatag aaaaggtctg catcatgacg gcacacaaat tcttcatttt catcaatatt
    42901 tttatataaa acattgtaaa gatgttttag tgtcaaattt ccctttttac tgccaaaaca
    42961 atcatttatt agcttaaaat cttttatatt tatagctacc atcatgtaag tactatcagg
    43021 tgattctaaa attaaaggtt ttactaagat actgaattta gttgaattta taccatttgt
    43081 tatactatct aaatatgcaa tattctctat ttgatttaca tattttcttc ttataatata
    43141 taaaatcaat gttataattc caataataca tgtaattata aatgtcatta ttattgtaaa
    43201 agagtttaac ttattaagtt caccaagtac agcatcttca ggtactataa gaacaaaatg
    43261 ccaatcattt aaaccttttg taattggata ataggttaat aggcattgta caccttttga
    43321 tgaagttatt gtaatatttc ctgatttatc atttttaaaa tcattaagca tcttttgtgc
    43381 ccaaggttca tctccagaac tcttatattt atggccaagg tcttttatta attcagtatt
    43441 tttccctatg aaaagaggtc ttccctgact gttaataatt tcaatagttc cttctccatt
    43501 aaagttatct atattaagaa tctcgtccat actttcttta ttagatacac ctatcaaaat
    43561 actagacact tcatgattat cattgaatat aggtacacta tagaaaacaa aacccattga
    43621 ctctattact tctgagtatt ctttaccttc aattcctttt ttgtaggaat cagtattctt
    43681 taaatcaaac ttttttccgc ttaaaaattc agctttaccc tctaaatcta ttattcctat
    43741 atcataatac ttgtaactag tctttctttt agataaatac tcatatcgac tatcaccttc
    43801 atattgctta ataaaatctg ccattattct taaatcggat aaaataaatt tgattttaga
    43861 atcaacattc attacaatct gtgtagatac atcatttaaa tagtttttag attgtttact
    43921 agatatattg tgtagtttta cagtattaaa aacagtaatt acaaggattg aaataataag
    43981 tgaacataaa attatagaca gaactaaact atttttctta taccttgata atttcatttt
    44041 tttcctccaa attataaacc tattttttaa tgtatattga cacttacaaa tttttttact
    44101 aagaaccctt cacactatat tatattatag tattccattt attaatattc aataatacaa
    44161 tcttaacatt tcattaatat ttcatatata ataattttat taaataatta tattatatgt
    44221 aatttttaat atttattgat taaaaacatt atgacatgtc atatatcaat aaagaactat
    44281 acctaaattt ggtatagttc tttattttaa taacaccttc gatattctat aaaaaatcta
    44341 ttacaatagc tactgcttat ctcctctaat aatatggcaa ttatatcata atctatagta
    44401 ttagatagta ttgattttga aatgatgtgt ccacctatcc aaacatcatt tctaattttt
    44461 taacttgagt agttgtagtt ttacaaaact taaatctatc atccattttt tatacaaata
    44521 gctcttattc ttactacagc aaatataaaa taaactatat ttgtattaca atttatcatt
    44581 gtatcatttt ttatttattt ttaaatttta tccgaaaaat ttagattgcc cttgcatata
    44641 acaccatgtc aggatatatc atccacttag agaggtgaaa tataaatgat aataaataac
    44701 tatcaaaatc aaagtatcat cacaaatcct aaaaaatttg aaaatgaata tcaatattta
    44761 ccagatactc caattgaatt attaaaagtg gttcaaaacc taataattca tggagaccaa
    44821 ggaaaactat acggtatatc ctttaataag caacaatctg atgaagaatt gcttcgtaca
    44881 gttcctcaaa tgttaaaaag aatatttgaa ataaattcta actcactaac tattccaaga
    44941 accccaaaac aaagacttgt tggaatgtgc agagattatt ctttacttct tgtgtccttc
    45001 ctaagatatc gaggttttga agctagaatg agagcaggtt ttgctaatta ttttgaaagt
    45061 gaacttactt atgaagacca ctggcttgta gaatactatg atactgcaac aaagagatgg
    45121 ataaaaatag atgcacaaat agatgacatc caaaaaaatt attttcaaat taattttgac
    45181 gctcatgatg tcagaagaat agatggcttt ttaactggtt cagaagcttg gataaaatgt
    45241 cgacaagagc atactcatcc agatgacttt ggatataata aaaattggaa aggttggcat
    45301 tctgtaaagg gtaatcttct acatgacttt aataatatga ttggtttgga attacttcca
    45361 tgggatttat ggacagaatt aagttccaaa aaatacaatc aattaacaag agcagaaaaa
    45421 aatttattag atgaaatggc agagatatta tcaagcggaa ataaaaaaat agaagacctt
    45481 aatttgttaa tagaaaaatt gcctgaagat tatttgaaat caatcttttc tcagttaaaa
    45541 atattaggta tttcggaaat aaaagaatta gctaatcctc ttgaactaga aaagaaattc
    45601 aaatttacaa aagcaataaa taaaccaatt aaaaattcac tttgtcataa taaaagctct
    45661 atctatttaa aaggaggaag acaaaacaat ttaaaagatg ttgaagttac aattccaaag
    45721 aataaaataa ctgtgattac aggtgtaagt ggtagtggaa aatcttcttt agctttcgac
    45781 acgatttacg aagaaggaaa aagacgttat tttgaaaatc taggtaatgg agcaaaactt
    45841 tcagaacagc ttcaaaaacc ggaatttgat ttacttcagg gattaacccc tactatagct
    45901 atcgaacaga aaaaaggaaa ccaaaatcct cgttctactg ttggtactct tacaagcatt
    45961 tgggactact taagaatgtt atttgtatca atcggaaaaa gttactgtcc atattgcaaa
    46021 actccattag aaaaaaagaa taatacaaaa aattattgtc cacattgcca aactattttt
    46081 tctaagataa atacttcaac cttcaatgct aactcccata ctggagcttg tcacgattgt
    46141 aatggattgg gttttaccta tcaagttaat cctcaattaa ttgtaaaaga cccaactatt
    46201 tcaatattag atggagctac ttactatttt ggaaaattga gggggaaaaa gccaaatggt
    46261 aattggatgg taggtgaatt atatgcaata gcaaaagata aaaatataga cctagatata
    46321 ccttggaatg aattgccaag agattttata gatgcaatct tatatggtac agacgataag
    46381 atatacgaat ttagttttga atcaagggga cgagaatcaa agattagaag acctgcttca
    46441 ggagcaatca accacattca aagacttttt agagaatcta gttctgaaaa taataccctg
    46501 catcaatata tgaacaaaat tccttgcaat acatgtggtg gcgaattgct gtgcattgaa
    46561 gctaggttca ctacaatcaa aggttatcgc ttccctgaac taacaaaaat gacgatagaa
    46621 cagttatgga attggttgtg tgaattgaca aatcaacttc aacaaaagga gctatcttta
    46681 gtaaatgata tattgacaga attaaaaatt cgagttagtt atctattaaa ggtaggtctt
    46741 agttatttat caacagatag aacagctcca accttatctg gaggagaact acaaagagta
    46801 cgattatcaa gtcagctagg aagtgaatta gtaggattaa cctatatttt agacgaacca
    46861 tctattggtt tacacccaag agaccataat ctaatcatca aaatgataga agaattaaga
    46921 gataagggta atactgttat agtagtggaa catgataagg atacaatact gtctgctgat
    46981 tatattattg atgtaggccc aaatgctggt ataaaagggg gcttcatcat tgcagaaggt
    47041 acaacccaag aaattataaa aaatccaaat tctataacag gcaaatattt gagtacatac
    47101 aataagataa gttcacaaaa taaaattata ccaagtaaat ggttaagctt aaagggatgc
    47161 catgcaaata acttaaaaaa tattgatgta gaaattccct taaactgtat gtgctctatt
    47221 acaggtgtta gtggttctgg taagagttct cttgtatttc acagtttact tcctgctcta
    47281 gaagaaaaat taaaacaaaa atctatccca aataaaaatt atactgaact tactggattt
    47341 gatgctattg atgattttat cttaatggac caaacagcta ttggaaaatc tagccgttct
    47401 acacctgcta catatatcaa tatttttgat gaaattcgtt ctctatttgc tgaaactcca
    47461 caagcaaaac aaaaattatt ggatgaaagc tattttagct ttaatagcaa aaaggggcaa
    47521 tgcccaaact gtcaaggatt aggtaaaaca aaaattattc tacaatatat agcagaccaa
    47581 tgggtaactt gtaataaatg tcaaggtaag agatataaaa aagaaatact gtctatacaa
    47641 tacaagggaa aagcaattgc agatatactt gacatggaag tagcagaagc aaaaacattt
    47701 tttagtgatt gctctgatat atatagaaaa ctctacttat tagatgaagt gggacttggc
    47761 tatctaaagc ttggacaaaa tacattagga ttaagtggag gagaatctca aaggataaaa
    47821 ttagcaaaag aattgggaac aaaaactaaa aaacgaatgt tatacatatt agatgaacct
    47881 actactggac ttcattttaa agatatagaa aatttgttaa ttacttttag aaaacttgta
    47941 aatgagcaac attcactttt aattattgaa cacaacacag aggttatacg tgcttctgat
    48001 tggattatcg atataggtcc agacagtgga atgaatggag gggaaattgt cgcttctgga
    48061 actcctgatg aaataaaagt aaatccaaat agtattactg gacattttat ataaaaacaa
    48121 ctaaataaac atggacttag acataaaatt atagaatatc ttatattatg gaagaattat
    48181 tataatagta gtataataaa aaaattaact ttagtatatt gtttgtgata aaatatgaat
    48241 aatctataaa atagagtata agaattatta tgttttataa tagagaaagg aaaatcaaat
    48301 gagttggaaa catataaaaa taccaaatgg agatacaatg attttttgta actcatttat
    48361 tactagcaaa ttatctatga atattattgt tacacacact cctattgtca ctacgcttga
    48421 gatgcaaaaa gcatacgaac catttactaa atataatgta aatatatttg cttttgattt
    48481 ttcaggaaca ggaaaaagtg atggatatga aaaagatttt tctcgcaatt caattataaa
    48541 agacttagat tctatcatta catacataga aaaaaattat tcttccaaca tacatctata
    48601 tgggaataca gggattggtg gcatgtttgc gcaatattat gcatgttcag acaataagtt
    48661 aaaaagtttt gctcagtttg cttgtgttga ttataaaaac acaacaggag taggctatcc
    48721 ctatctcact gttaaattat taaacctttt ctttaagttt cttcctaatt ttcacataac
    48781 agtaaaacca cctaaatata aaggttataa tgaagtctat gataatgaat tttataaaat
    48841 atttgaagag aaaaatcctc atatttggaa aaatagtaca aagataatta atacaatgtt
    48901 agagtgcttt attgcagaag atagtaagat aaaagatgga gtcaacatac ctactcttgt
    48961 ctttaaaaca cttcatgata gatattttaa aacccaatat tttgatagct attataattc
    49021 attaaaatgt aaaaagaagc ttgttgaaat taataatgtt cataatagtt actatataga
    49081 tagtgagaaa ttttgccaag aagcttatga ttggtttgta gaaaaccagt gatataatct
    49141 aaatgttata tggatttctg attatctttt cagaatttat taaaaatcca aatagcctta
    49201 ctttattggc tatttggatt taagatataa aaaaatagat atcctttact tatcaaaaac
    49261 ttataaataa aaaaatattc ccagtatacc acttattatt ataatgacaa taggattaat
    49321 tttccactta cgtactatca gtagcgtaac aaaaaagatt attagtgcag tccagtttag
    49381 catctcaaat atagaattga agtacacttt attcgtacca aataatgcaa ggattataat
    49441 tgtagccgca gctgagataa ttaaacctaa tgaagctgat tttagaccat ttaatatttc
    49501 aaatatataa gtagagttct gatgcttttg aaaaaaatta tataaaaata gagatattac
    49561 tacaccacat aatacacaac ctaaagtggc tgcaactgct ccccaaaacc ctccaatttg
    49621 aagcccaaca aaagtagaag tattaacagc caatggtcct ggtgtcattt gcgaaatagt
    49681 tataatatct gtaaacattt tctcacttat ccatccagtt tgatttacta ctttctcttg
    49741 gattaaaggt atgattgcat agccaccacc aatactaaac aagcctattt ttaaaaatat
    49801 aaaaaataag ttccaaattg tattcattta tttttcctct tcttgtagaa aacttgcatt
    49861 acacatacac aacagcaaac agataatata aaaattacat ttatactcat cacaaagttt
    49921 gcaaagaaag caataggtat catagctgat aaaaatagag aacgttgttt taatatcata
    49981 gagcacatgt caataatcaa atccacaatt agtgcagcaa caccagcttg cattcctttt
    50041 aatactgcag ttacaatagc attagatata aaagtggtgt aaaatgctga tactaatcca
    50101 agaataacga gtggaggtat tatagctgct atacaactaa tgacaacccc taaagtacca
    50161 gctactcgat aacctgccaa agcagataaa ttaattgcaa tagctccagg agttgattgt
    50221 gcaactgctg ccatactcat caaatcatct tctgtaaaga aatgcttttg atttacaaaa
    50281 taacgtctaa tcataggtac aactacatac cctccaccaa aagtgaatgt gctaataaac
    50341 aagttaataa ttaaaagcca aaaatatgtt tttctgcttt gattcaaaat attcctcctt
    50401 cttttcactt catattattc agtatacctg ttgctttgca atctgtaaaa tgatagaatt
    50461 taatggaatt aatcaatttt attcatgtct agtgaggata tttattatga taaacatacg
    50521 atatttagag attttagaag caattgaaca aacaggtact tttacaggtg ctgcaaaaaa
    50581 attacatatc acacaatctg ctgtatctca tgctatagct gaacttgaac aacaagctga
    50641 aacatcatta tttgacagat taccacgagg ggtatgtctt actcgctgtg gcatttctct
    50701 tttagaagaa gcacgcagta tcttaactgc ttgtcgcaat ttagacaaaa gaatcagtcg
    50761 tttagaggaa tgtacaccta taaacattgt ttctagcatt acaattgcct cttttttact
    50821 tccaccaatt ttaagtcgac taaaaaattt gttcccatct cttaaagtga atgtacgtgt
    50881 cgaaagtgct aattcagcca tggatatttt aaaaagtgga gaagctgata tatgtttttg
    50941 ggaaggtata gaaccacagg gggcattccg tacaatttta ttaggttcct ataagttatg
    51001 tgttgcatgt gctccaactt ttcctttatc tgaacaaacc ttatctctac gacagttatg
    51061 cacgtttccg ttattgttac gtgagcaagg aagtgctatt cgcgatactt tagacagtgt
    51121 attatctctt tcaaaccaaa aggcttatcc tatttgggaa agtgttaatt cttttgcact
    51181 tattaaagct gcagaagcag ggttaggtat aaccattttg ccagagaatt tattattaga
    51241 ttcactctta cataaaaaat tgcgattgat tgaattagat gggatagata tggaaaataa
    51301 aatgttggca atattacata aggataaaaa tattacacaa cctttgaaaa taatattaga
    51361 taatataagc aatgtacttt aatttaaaga tttaattttt taacattcta ttttttagca
    51421 taaaaagtgt gtactattcc ttaatgttgt gattttaatt ataatcactt tttaaaataa
    51481 tacacacttt attttaagta caatctaaac ttaaataaga taaaagtttc tattgtatat
    51541 gttttaaatt aatactatat tcttgtttac ctttttcaat tttaaattta tcatttttat
    51601 taggataaat agttacaaca ttatctttat actctgattc atcacatttt atattaattg
    51661 gcataacttc agcttcacca tatacatagc taacaggctt attattattc attacaacaa
    51721 tctgcaccat gtcatcaccc tttggagatg atatatttct ccatttatat cctattgttt
    51781 tatatatatc atctgcagat gttccagatt taaaaacata tattttatcc cattcaggag
    51841 tctttacttc tgataatcgt atttctttct tatctttact tactttatta attgaagaaa
    51901 taaattctcc aaatttgtca ctttcttgat ttttttcaaa tttaatcaat ttactagatt
    51961 tgtcaactat attccattta tcattggttt tttctaattt aaaattaatc ttagaaatac
    52021 attctccatg ttttcctggc tcagtgacta taacattttc tcctgattta tttttataat
    52081 catgttgctc aatttgaaca tgattatgac ctgcaactat agcatcaatt ccatcaactt
    52141 gttgagctaa atcttgtatt ctatttcctg ggtttctagg cttcttaggt ttctcacctg
    52201 tatgtgccac agcaactata atgtcaggct tctctttttc cattatacta acccactttt
    52261 tagcatcttc tactaaatca ttcatataca attcaccatt gtagccctct tggtctttta
    52321 gttctaaaga cttagagtca acaagttttc catctttcca ctgtttcctc tcaccaactt
    52381 cttttatagt aagccctaaa attcctagtt ttacgtttcc ttcaggtgta ttaatatttt
    52441 ttattatgta tggttttgta taactgtctc catttttttt gtaagtattt gctgataaaa
    52501 tatttatttt ttgcttctca aaatcagata tcatattatc cagataaaat ttattgttgg
    52561 atataaattc atgattccca agaactgcaa catcataacc tacctctttc atatcttttg
    52621 aaataggcgt ctcaatgtaa cgctcagtgt tactatcaat atccttattc ctagcactaa
    52681 aataactatc catgctagaa ccagatactt ccccactctg aacctcccat gactaaagtc
    52741 acagggttcc tgcttcatag aattttgcat actaaaatat gtcttactaa ttctccacag
    52801 gctatcccca tagttcctac ggttcttaca taagttattt attttgaatt gttattagtc
    52861 ttaatccttc ttttagtata tttatacttg catttatatc tctatcgtga gtttcattac
    52921 aactaggaca aatccattct cttatattta agttcttaac ttcctcgttt ttataccca
//
LOCUS       DBGJFK010000023        52794 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.023, whole genome shotgun sequence.
ACCESSION   DBGJFK010000023 DBGJFK010000000
VERSION     DBGJFK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52794
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.023"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..198
                     /locus_tag="ACOIAP_001572"
     CDS             <1..198
                     /locus_tag="ACOIAP_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638460.1"
                     /translation="GYYNILLELLSGKLSFECESKVYVFIGLKFYVYKINLLTESYKK
                     TRYFLEGVIREYFFVVKLTEE"
     gene            471..4016
                     /locus_tag="ACOIAP_001573"
     CDS             471..4016
                     /locus_tag="ACOIAP_001573"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2638461.1"
                     /translation="MNRLKPRILGISILFIIIIILTCGAIFKFKFKLDNKLKETTHTY
                     LSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDKMVIDLMDSNVKRSSLMRMT
                     ISTLDGECYSNDGIIRNVQDRDYFKKAKNGERNISEPLKSIVNNKEIIVLSTPVYKSG
                     KIVGVLSGIYDSKKLNELLGLSAFDEKADVFVANKNGAIIAQKTNKNSKTLSCIFQLF
                     NKNNCDEVYCLKTIKENMKNDKSGYFNYDLDNEKFMLNYQPLGVNDWYVFSVVPNKIV
                     SIQSENISYDVYVFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGGV
                     KTCLKDEYMTMTYVSQGFLELTGYSDEDLNKIFKNRFKDMIYKDDLDKFNCIILNQLE
                     KQDKIEVEYRIVKKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSKR
                     FEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLKDELNNKLIKLIFKD
                     DRIGLINSINKQLKLSDTFASEQRVEKREGTIIWILLKGRKIIYENGKSVLCCVIVDI
                     TSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENAT
                     KNIIKSVDIYHDDMDKFISLIKLTSEGSEYEEREIRLRTRDTTYAWFSIKATTLFDNN
                     GKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKGA
                     LMIIDIDDFKGINDNLGHLYGDAVLSEIASDLVNLFRATDIVGRIGGDEFIVFIKDIS
                     ETRDIINKAEELVKTFERSFLGKGRKYKISLSVGIAKFPQDGMDYMTLFRNADIALYS
                     AKGKGKNCYTLYDKKIDKVKYIINTRSTEDIDNVEKSFKEHITNYIFDILYESSDIEV
                     AVNLILSIVGKHFNVSRMYIFENSDDNLVCKNTFEWCNEGITSEINNLKNIYYKDLGN
                     YLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGSEFRGFIGFDECSYN
                     RMWTNDEVNTLTFISKTLGMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTYE
                     LLFINKKMLESAPNTHVGDLCYKAIWNNQNKPCKKCPMIYLKDGDDTYKSFMRNKKFE
                     IQANITTTTLKWFDGKDACLIFGSEVTSIESEENT"
     gene            4201..6135
                     /locus_tag="ACOIAP_001574"
     CDS             4201..6135
                     /locus_tag="ACOIAP_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HGZ2638462.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLENAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHRDKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLNREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACNKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKSEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRINKNQQKSSTRKKKKH"
     gene            6241..7236
                     /locus_tag="ACOIAP_001575"
     CDS             6241..7236
                     /locus_tag="ACOIAP_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MqnA/MqnD/SBP family protein"
                     /protein_id="HGZ2638463.1"
                     /translation="MKKYISIILLVVMAMVVLVGCSPGKDNSQNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKDGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     DYSDINFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7208..7993
                     /locus_tag="ACOIAP_001576"
     CDS             7208..7993
                     /locus_tag="ACOIAP_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638464.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIILNSSFYIDILYSIGRCFFSFLLAMFFAIILSIVSYLNRFFRN
                     LLKPINALARSIPTMILVVLALIWFEKDSTPFIVGFAIVFPILYDNVLGAILNIDKSL
                     LEMASVYKIRFIDKVLKIYLPVIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7981..8679
                     /locus_tag="ACOIAP_001577"
     CDS             7981..8679
                     /locus_tag="ACOIAP_001577"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638465.1"
                     /translation="MEKIRLSIENINKRYDNRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNKVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTKLNKICDEYLELVGISEYKKFYPQMLSGGLRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFKNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSNELEKNEVLKLI"
     gene            8802..9275
                     /gene="ybaK"
                     /locus_tag="ACOIAP_001578"
     CDS             8802..9275
                     /gene="ybaK"
                     /locus_tag="ACOIAP_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HGZ2638466.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKFTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9472..10311
                     /locus_tag="ACOIAP_001579"
     CDS             9472..10311
                     /locus_tag="ACOIAP_001579"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HGZ2638467.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLGCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEVGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTSINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10324..10872
                     /locus_tag="ACOIAP_001580"
     CDS             10324..10872
                     /locus_tag="ACOIAP_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HGZ2638468.1"
                     /translation="MIKITTPVSEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10938..12119
                     /locus_tag="ACOIAP_001581"
     CDS             10938..12119
                     /locus_tag="ACOIAP_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HGZ2638469.1"
                     /translation="MSKDYAKLALEMHEINKGKISVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAVINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALESSVENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12411..12800
                     /locus_tag="ACOIAP_001582"
     CDS             12411..12800
                     /locus_tag="ACOIAP_001582"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2638470.1"
                     /translation="MMEYKVNDQELNASMFVPFVNRIWPGDYDMDKTQTALSKTLNIT
                     AYDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQ
                     PGVEAFYEKNGCQRSLQSYIIKKKDSY"
     gene            12950..13213
                     /locus_tag="ACOIAP_001583"
     CDS             12950..13213
                     /locus_tag="ACOIAP_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HGZ2638471.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13734..14417
                     /locus_tag="ACOIAP_001584"
     CDS             13734..14417
                     /locus_tag="ACOIAP_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2638472.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGEFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            14428..15669
                     /locus_tag="ACOIAP_001585"
     CDS             14428..15669
                     /locus_tag="ACOIAP_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2638473.1"
                     /translation="MKIFSNKDIKMFFLILISILVMFIIVGQIVLISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVVHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFIPYMYFFRQQSKIEEASYKIDSFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIVLNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISIKGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSTFTISFLKLTNM"
     gene            15741..16424
                     /locus_tag="ACOIAP_001586"
     CDS             15741..16424
                     /locus_tag="ACOIAP_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638474.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            16421..18751
                     /locus_tag="ACOIAP_001587"
     CDS             16421..18751
                     /locus_tag="ACOIAP_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638475.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDSGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANTGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KQEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNGNAEKELEVGG
                     ILSSIPFEVKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTSGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAVSGCLLGSILGLMLHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPVKKICELDIIDSINAQ"
     gene            complement(18932..19774)
                     /locus_tag="ACOIAP_001588"
     CDS             complement(18932..19774)
                     /locus_tag="ACOIAP_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1-like domain-containing RNA-binding protein"
                     /protein_id="HGZ2638476.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVARLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            20070..20804
                     /locus_tag="ACOIAP_001589"
     CDS             20070..20804
                     /locus_tag="ACOIAP_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2638477.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGNPIEYTISIFRTDKYQYEIVLSE"
     gene            20814..21947
                     /gene="nagA"
                     /locus_tag="ACOIAP_001590"
     CDS             20814..21947
                     /gene="nagA"
                     /locus_tag="ACOIAP_001590"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGZ2638478.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYEQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GDYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAISLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            22046..22795
                     /gene="nagB"
                     /locus_tag="ACOIAP_001591"
     CDS             22046..22795
                     /gene="nagB"
                     /locus_tag="ACOIAP_001591"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGZ2638479.1"
                     /translation="MRVLVCKDYDAMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYKTVYGEITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPNDYKLV"
     gene            22970..23242
                     /locus_tag="ACOIAP_001592"
     CDS             22970..23242
                     /locus_tag="ACOIAP_001592"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638480.1"
                     /translation="MLKIIILSGILSSIIKLPIIGILPTGNIKKNTGINDSKKDGKQR
                     RSNLGISIYQLPLFLYSPINNSVPSNKPIPPEEIRLIKIYLLKSCI"
     gene            23902..24606
                     /locus_tag="ACOIAP_001593"
     CDS             23902..24606
                     /locus_tag="ACOIAP_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2638481.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNLVNMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKVWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            24608..26095
                     /locus_tag="ACOIAP_001594"
     CDS             24608..26095
                     /locus_tag="ACOIAP_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2638482.1"
                     /translation="MKNGNDKNIIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTETVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTRENDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLVLFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSNVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKYASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEKMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKHNQKNIVVIVEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIINKHGGRIYVENGKKGAKFTILFKL"
     gene            26300..27913
                     /locus_tag="ACOIAP_001595"
     CDS             26300..27913
                     /locus_tag="ACOIAP_001595"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2638483.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGLCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFIKEGFEIMFENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     FPLFLIPIFSLFLSVSVFDVSKFFSLECLKFLSLISSIGILYINFIVFYLFKFIIDKT
                     KLSMKYEILEKEIIHKEELRLSNERYKIIVEQTDSVVFEWNIKENKSFVSQAWNEKFG
                     YNNVCKNIFKEIKDKDLVHSEDNAIFENFLESIKKKNRHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELKTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQASFGSRDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(28128..29105)
                     /locus_tag="ACOIAP_001596"
     CDS             complement(28128..29105)
                     /locus_tag="ACOIAP_001596"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGZ2638484.1"
                     /translation="MIQCEIADRNSDKKINTLEVIIFFVVTYGISLLFGIPLYFKKYM
                     NPQIMVTFMTILPASGVAITKIYKHKKSDEHIILHCVIIADFLLSLFLVTLKAFGVID
                     DETILLGMGILVLFTGIITICYACLEGKELYPFKNVNKSIICIFIFIIIINLSKCIML
                     GWKDINFINLIMNIFLIFPYIANQSILFFGEEYGWRGFLQEKMQTKFGKRMGVILLGI
                     IWELWHIPLWFTVYHVDVLGILLRLFSVISLSIFFGYVYMKTKNVWSCVVIHLINNTV
                     LLDTDLNNAFLNFNASSLNSSIILGCLIFSVLLSLFIFSKEYKKEQLRY"
     gene            complement(29122..29952)
                     /locus_tag="ACOIAP_001597"
     CDS             complement(29122..29952)
                     /locus_tag="ACOIAP_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2638485.1"
                     /translation="MSQVPKNYFTTGEFAKICGVNKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLKEIKMPLKEIKTYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPITYKEQFLGDEEENFLYECI
                     NFIDNYELSDYGMIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKQKGLYVTA
                     YHKGSYETIYKTYEKLLNFFSQNNLCIGDFVYEEYLLYDISVRDSNEYLTQISAEVKI
                     "
     gene            30025..31752
                     /locus_tag="ACOIAP_001598"
     CDS             30025..31752
                     /locus_tag="ACOIAP_001598"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638486.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGI
                     VKGDIDYIVKTGLMMIIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKVMTIIIV
                     VVMFLFMLSAFLVGKRLIRLFKIMQIKMDNMNRVLREVVTGVRVIRAFNRSHFEKKRF
                     DKTAIDYSETAISINKVFSVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNVYKDDVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISL
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            31790..33652
                     /locus_tag="ACOIAP_001599"
     CDS             31790..33652
                     /locus_tag="ACOIAP_001599"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638487.1"
                     /translation="MSEKRTDKQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLVSAIFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRRAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPRGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHEELIEKKGFYEELYNSQFSSEYDEDVV"
     gene            33983..34672
                     /locus_tag="ACOIAP_001600"
     CDS             33983..34672
                     /locus_tag="ACOIAP_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HGZ2638488.1"
                     /translation="MDKKLNYRFEMKHKITEADVLALKSRLYPIMKKDKNALKDGKYL
                     IRSLYFDTPEDKALLDKLNGVALREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSASL
                     TKTEVIKILNNDIEFLKESTNCLLREFYLKIKCERLEAKSIVDYDREAFVYPVGNVRV
                     TIDSDIKTSVNSIDLFNKHLPTVSIIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            34771..35445
                     /locus_tag="ACOIAP_001601"
     CDS             34771..35445
                     /locus_tag="ACOIAP_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HGZ2638489.1"
                     /translation="MTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMVYKKT
                     YMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDPMDLV
                     FLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNEDSEDI
                     ATDKIKKAFTKYQIKSKSVTPEKGIELVFEIRMKDGETSLINDLSQVDGVTNAVLVSY
                     NGDYVA"
     gene            35462..37327
                     /locus_tag="ACOIAP_001602"
     CDS             35462..37327
                     /locus_tag="ACOIAP_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HGZ2638490.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGIYSTSGNKGVDLYSDVYIEKYF
                     NRDKVMEVNIEIAESDLKDMNENAIKEEFKVAKVTIDGDTYGNVGIRTKGNSSLTSVV
                     NSDSNRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLSTPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGDVTGDLYKSDEGSSLQYKGDDPENYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLYNLIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDRNNSNNNSGNKSDEKEVTAELTLSEVKTNMDNETENNTTG
                     DSKNKNNTNDDKSGNGNNQKPEGSMGKGGKSIPGVLEVAKDMSKTIKAQLNGETSSTK
                     QNSGDESSSENKGTEKFDEDVGGMPEPPEGMDGKMPPGMGNMDNGDMNGKNGNMNRNQ
                     GNPREAGGFENKGGGSMSKTRTYSKLILGGASMIIMLIMLVGVSNINRRRFIKSK"
     gene            37709..38398
                     /locus_tag="ACOIAP_001603"
     CDS             37709..38398
                     /locus_tag="ACOIAP_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2638491.1"
                     /translation="MLQKVLWKFLKLVFGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLILLAVGMVFYMGSGLGSGPRDGLMVALQKKTGKSINLIRGIIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAATQNIVK"
     gene            38834..39373
                     /locus_tag="ACOIAP_001604"
     CDS             38834..39373
                     /locus_tag="ACOIAP_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGZ2638492.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            39392..40435
                     /gene="potA"
                     /locus_tag="ACOIAP_001605"
     CDS             39392..40435
                     /gene="potA"
                     /locus_tag="ACOIAP_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:1902047 - polyamine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein"
                     /protein_id="HGZ2638493.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKESN"
     gene            40437..41273
                     /locus_tag="ACOIAP_001606"
     CDS             40437..41273
                     /locus_tag="ACOIAP_001606"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638494.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYIKVFGRSILLAGGATLICLVVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            41378..42052
                     /locus_tag="ACOIAP_001607"
     CDS             41378..42052
                     /locus_tag="ACOIAP_001607"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638495.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGTK"
     gene            42052..43104
                     /locus_tag="ACOIAP_001608"
     CDS             42052..43104
                     /locus_tag="ACOIAP_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2638496.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPIDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITENPVAYPSKEVLNKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            43363..44211
                     /locus_tag="ACOIAP_001609"
     CDS             43363..44211
                     /locus_tag="ACOIAP_001609"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2638497.1"
                     /translation="MNIVNKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSIVGLITSSIIIFMYTSYILYNNITYNMDVEFISYMWIIAIPISSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGESKTNKIVKYIGSNIIECTRNEDIIYSLQKDMLGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYRDSFGDSINFKNIVEE
                     ELQYDV"
     gene            44201..45865
                     /locus_tag="ACOIAP_001610"
     CDS             44201..45865
                     /locus_tag="ACOIAP_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2334 domain-containing protein"
                     /protein_id="HGZ2638498.1"
                     /translation="MMFKIFNKSLLKLVAILSIVLIISNFSLSSYASEITSRTDNVLI
                     VYDSKKETDYNRDILNIMRTLLGRFSSDIKLLKLSNYDGEINKNYYSHIFILGINENS
                     YDNDNKTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYIGKTNNIVSVNYRGKSY
                     NLEEHYIFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKRFDKGRIFVRIEDVHAFRDPKDLVNIADYLSSKDIPFTIALIPAYVNPK
                     NHKITTLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLSGLRVCIENGIYPLAFEAPHYAMESDGYKELKKYFSTYMGQHQNNN
                     KKFSTNTYPYIIRDTEEFNILIPENLGYIDPEDKFTFQHIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDRDLEE
                     NIKSDIRFKSISNISKILIFIVSISVLIFMIIFIYFKRIDKKKFLK"
     gene            45914..47170
                     /locus_tag="ACOIAP_001611"
     CDS             45914..47170
                     /locus_tag="ACOIAP_001611"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGZ2638499.1"
                     /translation="MRDLNVSECLFVFSLCSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMVSILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILED
                     IKNKYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDRNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIKNIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            47193..49274
                     /locus_tag="ACOIAP_001612"
     CDS             47193..49274
                     /locus_tag="ACOIAP_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HGZ2638500.1"
                     /translation="MKKFIISIISLVLFFSNISLIDKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEDVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKVKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKMENSINEYPYPYAEIENNLKLDTTIVVPDNMTRGESTAVFNLASEFGKIIKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSTEEQTLLSSNCLIKQVDSPYNKN
                     KKMMVVIGSNEENLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIVLNLRYSDNLHFEKSLVTVSIN
                     DVLVGSKKLDRQHSNNDKLELKIPKDIDNKNYYQVKLVFNLNIKNSNCVTRESNNPWA
                     YVSNSSYLALSTKENEALSFESYPYPFVRNDEFNDLTVIMPDYSDSQAMTWMSKLGVT
                     LGANINSHNGNMNVIRGKEFSDKYKDTNIIVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FLSNDKLSFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKNSSWNMSINKTTKVFLMISFITIIVVIIL
                     SMLYIKKYKRR"
     gene            49311..50393
                     /locus_tag="ACOIAP_001613"
     CDS             49311..50393
                     /locus_tag="ACOIAP_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGZ2638501.1"
                     /translation="MKKYMNKFKLKRNILISVIVLIFIFIIYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEISQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNTILNEIIIDVANPL
                     DVNVLNIGSNFVHLEGYQQNWSEIIDFVQSKFDGLVTYRTNWWYTKKDDLNSKLSYEQ
                     KLNNNFFDKLDFISIAAYFELSNKRINTVDELISALYSSTVNNRRQNIKKEIYNLYKA
                     HRKPIFFGELGFSNREYASSQPWNHATSKVVNGEEQARCFEAYKKVFENEEWINGFSV
                     FCIGKIDDEKNFYPSKESIKVIKSWY"
     gene            50450..51574
                     /gene="wecB"
                     /locus_tag="ACOIAP_001614"
     CDS             50450..51574
                     /gene="wecB"
                     /locus_tag="ACOIAP_001614"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HGZ2638502.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRANIKSIVCVTAQHRE
                     MLDQVIETFNINIDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIVLVHGDTTTT
                     LATSLTAFYNKIIVGHIEAGLRTYDKYSPFPEELNRQLTGVIADMHFAPTNLAKKNLL
                     SEGKPYNNIFVTGNTAIDALKMTIKENYSHPIIDDIGNDRMILLTSHRRENLGKPMKN
                     IFKAIKRIVDDFEDVQVVYPIHLNPKIRTIADEIFGKFPKKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLREKTERTEGIEANTLKLVGTNEDRIYNSVSNL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            51682..52656
                     /locus_tag="ACOIAP_001615"
     CDS             51682..52656
                     /locus_tag="ACOIAP_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGZ2638503.1"
                     /translation="MARKLIKNLGKSKSAKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLVDVIRSYNLQLIDNKVETK"
BASE COUNT        20970 a         5426 c         9088 g        17310 t
ORIGIN      
        1 ggatattata atattttact agaattatta tctggtaaac taagttttga gtgtgaatct
       61 aaagtatatg tttttatagg gcttaaattt tatgtataca aaattaattt gctaactgaa
      121 tcatataaaa agacaagata ttttttagag ggagtgatta gagagtattt ttttgttgtc
      181 aaattaactg aagagtaatt aattagaaaa ggaatgaata ataatgaata tattacatta
      241 ttacttttga taaatcaaaa ataaggtcag agtttttaat attaattaag aatgatgaaa
      301 tatgaacaaa gattttacaa ataaacctta agctatgtta tttaattcta atgcgggaag
      361 aaggtaaatg tatattgaaa aaatcataga aataaaaata aacaacttaa ataaatacaa
      421 aggcttgcaa aataagtaat ataattatat acaatgagga tgtgagtatg atgaacagac
      481 taaagccaag aattttaggt attagtatct tgtttattat tataattatt ttaacatgtg
      541 gagctatttt caagtttaaa tttaaattag ataataagtt aaaagaaacc acacatacat
      601 acttgtctga gtttacagaa cacaatataa ttaatctcaa gacaagactt agtggtcaat
      661 ttgacatgct tgaatccatt gctaatttca taggaaactt gaataatata aatgataaaa
      721 tggtgattga tttaatggac tctaatgtaa agcgaagttc tttaatgaga atgactatct
      781 ccacattaga tggagaatgt tattctaatg atggaattat tcgtaatgtt caagatagag
      841 actattttaa aaaagctaaa aatggagaaa ggaatatatc agagccttta aaatctattg
      901 ttaataataa agaaataata gttttatcta ctccagttta taaaagtggg aaaatagttg
      961 gtgttttaag tggaatttat gattcaaaaa agttaaatga attattagga ttatctgcat
     1021 ttgatgaaaa agcagatgtt tttgttgcaa ataaaaatgg agctataatt gctcaaaaaa
     1081 caaataaaaa tagtaagaca ctatcgtgta tatttcagct ctttaacaaa aataattgtg
     1141 atgaagtcta ttgtctaaaa actataaaag aaaatatgaa aaatgataaa tctggatatt
     1201 ttaattatga cttagataat gaaaaattta tgttaaacta tcaaccactt ggagttaatg
     1261 attggtatgt tttttctgtt gtgccaaata aaatagtgtc tattcagtca gagaatatat
     1321 cttatgatgt atatgtattt gcattagaaa tactattagt tatattgatt tttataatat
     1381 atatagcatg tattataaat aataacacca aaattattat aaatgaaaaa gaaaaattta
     1441 aagtactcac tgataatata ctaggaggag ttaaaacctg tttaaaagat gaatatatga
     1501 ctatgacata tgtaagtcag ggatttttag aacttacagg ttactctgat gaagatttaa
     1561 ataaaatatt taaaaataga tttaaagata tgatttacaa agatgattta gacaagttta
     1621 attgtattat tctaaatcaa ttagaaaaac aagataaaat tgaagttgaa tatagaattg
     1681 taaaaaaaga tggaagtata atttggattt tggagagaag caagtctata aatgataata
     1741 aaggaagtga gtgtattcaa ggagttttaa ctgatataac agaacttaag aaaatacaag
     1801 aagagttaga ttcaaaaaga tttgaaatac aggccatcaa tgatagtatt gttggtggga
     1861 tagtgataac tgagataaat gatgattttg atagtatata tttaaatgaa ggttatttaa
     1921 atatgattgg atatacacgt aaacaactga aggatgagct aaataataaa ttaataaaac
     1981 ttatttttaa agatgataga atagggctaa ttaatagtat aaacaaacaa ctcaaattaa
     2041 gtgatacatt tgcatctgaa caaagagttg aaaaaaggga gggtactatt atatggattt
     2101 tattaaaagg aagaaagata atttatgaaa atggaaaatc tgtactttgt tgtgttattg
     2161 tagatattac ttctgctaaa ttattagagc aagaacttaa aaagagtgaa gaacgccatg
     2221 aaatcattct aaagcagacg caaaatatta taatagaatg ggatatagaa aaagacaaaa
     2281 tgaatatatc acccaattgg tataataagt ttaaatatga ccctataact gaaaatgcaa
     2341 caaaaaatat aattaaatca gtagatatat atcatgatga tatggataag tttatttcac
     2401 taattaaact tacttcagaa ggtagtgaat atgaagagcg tgaaattaga cttagaacta
     2461 gagatactac ctatgcatgg tttagcataa aggcaacaac cttatttgat aataatggta
     2521 aaccttataa ggtagtagga agtttgactg atattgatga atcaaaacga gaagctgaaa
     2581 agttaaaaga aagggcagaa aaagaccctc ttacagattt gtataataaa aaagcatcac
     2641 aatcacttat agaagaatac ataacattag ataaaaaaag aaaaggtgct ttaatgatta
     2701 ttgatattga tgactttaaa ggaataaatg ataatttagg acatttatat ggggatgctg
     2761 tattaagtga aattgcaagt gacctagtaa atctatttag agcaaccgat atagtaggta
     2821 gaattggtgg agatgagttt attgtattta taaaagatat ttctgaaaca agagatatta
     2881 taaataaagc agaagaactg gtaaaaacat ttgaaaggtc ttttttaggt aaaggacgaa
     2941 aatataaaat atcattaagt gtaggaattg ctaagtttcc acaagatggt atggactata
     3001 tgacactatt tagaaatgcg gatatagctc tttactcagc caaagggaaa ggtaaaaatt
     3061 gttatacatt gtatgataaa aaaattgata aagttaaata tataattaat acaagaagta
     3121 cagaagatat tgacaatgta gagaagtctt ttaaagaaca tattacaaat tatatatttg
     3181 atatactata tgaatcaagt gatatagaag tggcagtaaa tttaattcta agtattgtag
     3241 gtaaacactt taatgtgagt cgtatgtata tatttgaaaa ttcagatgat aatctagtat
     3301 gtaaaaatac atttgaatgg tgtaacgaag gtataacttc tgaaattaat aatcttaaaa
     3361 atatttatta caaggattta ggtaactatc ttttaaactt taatgcagat gggctatttt
     3421 attgtaatga tattgaaaat ttagggagtg atgtgaaaaa agtacttaaa ccacaaggta
     3481 tacgttcaat attacagtgt aaaattttag agggcagtga atttagaggg ttcataggat
     3541 ttgatgaatg ttcatataat cgtatgtgga ctaatgatga agtgaataca ttgaccttta
     3601 tatctaaaac actcggcatg tttttattaa aaatgcgtat tcaaagtaag ctagaagagt
     3661 ctttaacgat tcaaaagtct gtaatggata atatggacat atgggcatat gttgttgaca
     3721 ggaataccta tgaattatta tttatcaaca aaaaaatgct tgagtcagca ccaaacactc
     3781 atgtaggtga tttgtgttat aaagcgatat ggaataatca aaataaacct tgtaaaaaat
     3841 gtcctatgat atatttaaaa gatggtgatg atacttataa atcatttatg cgtaataaaa
     3901 agtttgagat acaggcaaat ataactacaa ctactttgaa atggtttgat ggtaaagatg
     3961 catgtttaat atttggaagc gaagtaacta gtattgaatc tgaagaaaat acttaaaata
     4021 ctgtgttata tatatactta aaattgcaat ttgaatttat tagacttaaa atgtctatat
     4081 aaatcattta agttgtggtt ttaagtattt tttatgatat aattaagcgt taagaacaaa
     4141 attaaaagat acttttgtat aaaaaaatat ttgttaaata tatattgagc aggtgataat
     4201 atggaaaata agtttttacc aataagcaaa caagatatga tagatagagg atgggaagaa
     4261 ttagattttg ttctagttac aggagatgct tatgtagacc atcatagttt tggaacagca
     4321 ataatatcta gagttctaga aaatgctggg tataaagttg gaataatagc tcaaccagac
     4381 tggagaacta cagatgattt tatgaagcta ggaaaaccta gacttgcatt tctagttaat
     4441 gcaggaaata tggattcaat ggttaatcat tattctgtaa gtaaaaagca tagagacaag
     4501 gacatgtatt ctccaggtgg gaaaatggga tatagaccag atagagctac tatagtatat
     4561 tgtaataaaa taagagaagc atacagtgat gtcgcaatag taataggtgg aattgaagcg
     4621 agtttaagaa gatttgcaca ctatgattat tggagtgata aggtcagaaa atctatgtta
     4681 atagatagtg gagcagattt attagtttat ggtatgagtg aaaagcagat tgtagaagta
     4741 gccaatgcac ttaatgatgg atatgacccg aaatatatta gacatattga tgggacatgc
     4801 tatatttcag atactttgga agaaatatat gataaatata tattaattcc atcttataaa
     4861 gaaatatgtg aagataaaat gaagtatgta gaagctttta aaattcaata tgatgagcaa
     4921 gacccgttta gaggaaatat aattgttcag cctcacggaa gtaagtatct ggttcaaaat
     4981 aaaccagaga aaccacttaa cagagaagaa ttagatgagg tatatggatt gccatatcaa
     5041 aagacatacc accctgtata tgaaaaattt ggtggtatac cagctataga ggaagtaaaa
     5101 tttagtatag taagttcaag aggatgcttt ggtagttgtt cgttttgtgc aataacattt
     5161 catcaaggta gggcagtaca aagtagaagt gagaaatcaa ttattgatga agcaatagga
     5221 ataaccaatt tagatgattt taaagggtat atacatgatg ttggaggtcc aacagctaat
     5281 tttagaagac cagcatgtaa caaacaaatt actaaaggtg cttgtaaaaa tagacaatgt
     5341 ttatctccat caccatgtaa aaatctagat gcagaccaca gtgaatacct acatttactt
     5401 agagctgtaa gaaaattacc taaaataaaa aaggtatttg tgcgttctgg aattagatac
     5461 gattatgtaa tggcagataa aaacaataaa tttcttagag aattgataga gcatcatgta
     5521 agtggtcagt taaaggtagc tccagaacat atatcagaag aagttttaaa gtatatgcag
     5581 aaaccagcag gaaaaaccta tgataaattt agacagaagt tttttgctat aaatgaagaa
     5641 ttaggtaaaa agcaatattt gataccttat ttaatgtcta gtcatcctgg ttctacctta
     5701 aatagtgcta tagagttagc agagtattta agagatactc actatcaacc agagcaggtt
     5761 caggattttt atccaactcc agggactcta tctacaacca tgttttatac aggtattgac
     5821 ccacttacaa tgaagccagt ttatgttccc aaatcaaaac gtgacaaggc aatgcaaagg
     5881 gctttattac aatatagagc acctagaaat tatgatttgg tatattctgc attagttgaa
     5941 gcaggaagag aagacttaat tggttttgga catagatgcc ttataaagcc aaaaagtgag
     6001 aagccttatt ttaatagaaa taattctaaa aaaaatgtat ctaaaggaac aaataaaaac
     6061 aaaaaaacta atacaaataa cagaattaat aaaaatcaac aaaaaagttc aactagaaaa
     6121 aagaaaaagc attaaagtgt aaataaaaat acttaaaaaa gaaggattat tcgataaatt
     6181 aacagaaatt agtataaata aatataatta ttttaaaggc gttacctttg ggaggaagag
     6241 atgaaaaagt atatttctat aatattatta gtggtgatgg ctatggttgt tttggtagga
     6301 tgttcaccag gaaaagataa ttctcaaaat aaggagttat cagttgtcaa acaagtgaaa
     6361 gtagctgttc cagatgggct accagcagtg gcaatagcca aacttgcaaa tgaaaatcca
     6421 gagattaaag atggatatga aacagtgtat agcattgaaa agacacctga ggcgatttcc
     6481 actagagtga tgaaaaaaga tgcagatata gctatagttc cttcaaacat ggctgcgata
     6541 gcttataata aaacttcatc atataatata gttggaactg tgggaatggg ttcactttat
     6601 ttggtatcaa cagaaaatat aaaagactat tctgatttag ttggtaaaga agttggatgt
     6661 actggaaaag gacttactcc agatataact ataaaaagcc ttttgttaca aaaggatata
     6721 gattattcag atataaattt taattatgta aattcagcaa gtgaattagt accattattg
     6781 gctactggta aagttaaaac aggtattgtt ccagaacctg cacttagtgc tttgatgtct
     6841 aaaaatccag atataaaaat tataaaaagt ttaaatgact catggaagga agtaagtggc
     6901 tcaaaagatg gttatcctca atccacttta attgtaaaat ctgagttttt gagagataat
     6961 aaagattttg ttgattcttt tgtaggtcaa ttatcaaata gtatagattg ggcaaataaa
     7021 aatcctgaag aattaggtgc atattctgaa aaaataaaaa tatctactga atcaaagata
     7081 ataggaaaat ctcttgaaag agctaattta aaatatattc cagttaaaga catgattaaa
     7141 gactataaaa attactatga gaaattagct aattttgatg ataagacatt aggaggcaaa
     7201 gtaccagatg aagcaatata ctttgttgag aaataaaaaa aataaagaac aatttataga
     7261 taaaatggag gtaacacttt cttgtgttat cctcttattt ttatggcaaa ttattgcttt
     7321 aaaaattgat aatgatattt ttttaccaac agtaggtcaa gtatttaata gcataaaaga
     7381 aattatacta aattctagtt tctatataga tatactttac tctataggga gatgtttttt
     7441 tagtttttta ctggctatgt tttttgccat tatactttca atagtgtctt atttaaatag
     7501 attttttaga aatttattaa aaccaatcaa tgctttggca cgttcaatac caactatgat
     7561 attggtagta cttgcactta tttggtttga aaaggatagt actcctttta tagttggatt
     7621 tgctatcgtt ttccctatat tatatgataa cgttttggga gctatattga atatagacaa
     7681 gagcttacta gaaatggcta gtgtgtataa aataaggttt atagataagg tattaaaaat
     7741 ttatttacca gttataaaat ttcaaattat atctatacta gtatcgacat tctctttaag
     7801 tttaaaagtt gctatagcag gagaagtata tagtcaacct acatatggta ttggaactat
     7861 gatacagact gaaaaaatta acttcaatac atctggaata tttgcatgga taattattgt
     7921 tcttttaatt tctgccattt tgcaaatagc tcaaaagttt ttagcaagga gagctttttt
     7981 atggaaaaga taaggttaag tattgagaat ataaataaaa gatatgataa tcgtattata
     8041 tttagagatt ttaatattga tttttatgta aatgaggtaa attgtatcct tggaaaatct
     8101 ggttgtggaa aaactacact cttgaatata ataagtggga ttattaaaaa tgataccaac
     8161 aatctaaata tcaaagaaaa tttaaataaa gtaggaaata aacttgaagc tagttacata
     8221 tttcaagatg atagacttat agactggtta acagtagaag aaaatataaa gatagttgta
     8281 aataaatact ataataaaac taaattaaat aaaatttgtg atgaatactt agaattggtt
     8341 ggaattagtg agtataaaaa attctatcct cagatgctta gtggaggtct tagacaaagg
     8401 gtaaatattg ctagagcttt tatatatcca tccaaaaaca ttataatgga tgaacctttt
     8461 aaatctattg atgcaaagaa tacacagctt ataatggata atttcaaaaa tatattaaga
     8521 aaagagaaga gaactgtgtt atttgtaact cataatattg aggaagcatt gtttttagca
     8581 gataggatat ttattttagg agattctcca attagaataa aaaaaatatt aaaaaattct
     8641 aatgaattgg aaaaaaatga agttttgaag ttgatataga gttataataa tactatcgtt
     8701 ttaaaacata tttgtttaaa atatataaga ctctgttaat atggtacaga atattcaaaa
     8761 atgtgtataa tgttcgtatt ttataaaaag gaagtgaaga tatggttaag actaatgcta
     8821 tgagaatatt agattcaaat aagattgatt ataaagtaat gtcttatgaa gtgaaaagtg
     8881 aacatgtgga tggtgttgag gtggcacatg atataggaag agatgtaaat gaagtgtata
     8941 agacattggt aactcaagga gttagtaaga atatatatgt atatgtaata ccagtacatg
     9001 aaaacttaga tttaaaaaaa gctgcaaaag tagctaaaga gaaaagtgta gagatgattc
     9061 atgtaaaaga tataaataag tttacaggtt atattagagg tggatgttct cctataggca
     9121 tgaaaaagct ttataaaact tttgtaaatg aaagtgcaaa gaatttagat acaattattg
     9181 tgagtgcagg aaaaatagga tatcaaatag aactatctcc atttgattta caaagactta
     9241 taaaagtaga atttgtagat gtaataaaaa aataagaatc acatataaaa tatagagatt
     9301 atattcttaa taacaggtgt tgtagtgtta ataaaatgaa taataatttt aaaataaata
     9361 ttcaattact tatgtgtaat tgatataaaa atattgagaa attttaaaaa caatggtaaa
     9421 gtgtaagtgt aatcacgaat attttttata aagtaatgga gggatgttcg cttgagaaaa
     9481 ataaaatctg aacaaatagt cgaacaagta aaaaaacttt gtatagaagc gagcctatat
     9541 ttaggagaag atgttttagg ttgtataaaa gagaaagcta aaagcgaaaa gagtgaagtt
     9601 ggaaaaaata tattaaatat attagttgaa aatgctgaaa tagctaaaga aaaaaatata
     9661 ccaatatgcc aagatactgg tatggctgta ttttttgttg aagtaggaca agaagtttta
     9721 attgaaggag atacgcttac tgatgcgata aatgagggag taagacaagg ctatgaagaa
     9781 ggctacttaa gaaaatctgt tgtaagccca attaatagag taaatacaaa agataataca
     9841 cctgctgtta ttcattatga tatggtaaaa ggtgataaaa ttaaaataga atttgcagcc
     9901 aaggggtttg gaagcgaaaa tatgagtaag atgaaaatgt taaaaccatc agatggacta
     9961 gaaggaatta aaaaattcat aatagataca gtttcagaag ctggacctaa cccatgccct
    10021 cctatggtaa ttggagttgg tataggtggg actgtagaca aatgtgctca aatagctaaa
    10081 aaggcacttt ttagagaact aggtgaattt aataaggatg aaaatatagc aaagcttgaa
    10141 agtgaactat taacatctat taataaactt ggtatagggc ctcaaggttt aggtggtact
    10201 acaacagctt tgggattaaa catagagact tttcctacac acatagcagg tctacctgtt
    10261 gttgtaaata taaactgcca tgcatcaaga cataagaagg tagtaattta ggaggaaaat
    10321 aaaatgataa aaataactac acctgtaagt gagattgata tagcaaaatt aaattgtgga
    10381 gatacaatta gcttgagtgg tatactttat acagcaagag atgctgctca taaaagattg
    10441 atagactgta taaataaagg tgaagaatta ccatttgacg tatatggtca aggaatatat
    10501 tatgtaggac ctactcctac aaagccagga gaagttatag gtgctgctgg accaacgaca
    10561 agctatagaa tggatgattt gactatacct cttttagaga gaggtcttag gttgatgata
    10621 ggtaagggaa aaagaagtga cgaagttata gaaggtatgc aaaaatatgg agcagtttat
    10681 cttgctgcaa taggtggagc tggagcatat atttcaaatt caataaaatc atgtgaaatt
    10741 attgcatatg aagatttagg agccgaagct ataagaaaga ttgtagtaga agaccttaaa
    10801 cttacagtag ccatagatag ctatggtaat aatatatatg aacaaggtcg agcaatttat
    10861 gaatgtaaat aaagtttaga aatttatatg aatattaaaa ttaaaaatag ttgtgtatat
    10921 tttaaggagg aaaattgatg tctaaggatt atgcaaaatt ggcattagaa atgcatgaaa
    10981 tcaacaaagg aaaaataagt gtagaaagca aggtagaagt taaaactaag gacgatttat
    11041 caacagcata tacaccaggt gttgcagaac cttgtttaaa aatacatgaa aatcaagatg
    11101 atgtttatag atacacttct aaagggaatc tagtagcagt agttagtgat ggaagtgctg
    11161 tacttggatt aggtaacatt ggtgctgaag catctatacc tgttatggaa ggaaaggcca
    11221 tattatttaa acaatttgca gatgtagacg cttttccaat atgtttaaag actaatgatg
    11281 tagatgagat agttaaatct gtagagttga tggaacctgt atttggaggt ataaatttgg
    11341 aagacatatc ttctccaaga tgttttgaga tagaagagag gctaaaaaaa tctttaagta
    11401 tacctgtttt tcatgatgac caacatggga cagcaataat agttgcagca gctgtaataa
    11461 attcaataaa gttaattgaa aacaaaaaaa tagaagattt agaaatagtt ataaacggag
    11521 caggggctgc tggtatagca atagcaaaga tactacttaa tatgaatgtt aagaatataa
    11581 tcttatgtga tagaagtggt gcattggaat ctagtgtaga aaatctaaac tatgttcaaa
    11641 aagaaatgtt aaaagtaaca aatataagaa atgaaaaagg acctttaaaa gatatcataa
    11701 aaggaaaaga tgtatttatt ggtgtttcag gtccaggagc tgttacaaaa gaaatggttg
    11761 aaagtatgtc tgaaaagcca ataatattgg caatggcaaa tcctactcca gagataatgc
    11821 cagaagaagc aaaattaggt ggagcattta taatgggaac aggtcgttca gacttcccta
    11881 atcaggttaa taatgtcttg gcttttcctg gaatatttag aggtgcacta gatgtcaagg
    11941 ctaaagagat aaatgaagag atgaagatag ctgctgcata tgcaatagct aatactataa
    12001 gtgatgaaga aatatgccca gagtatatat tgccagacgt atttaataag aatgttgtaa
    12061 aaaatgttgc taaggcagtt aaagaagcag cgataaaaac caaagtaaat agaatataaa
    12121 tttttatatg ttcatatatc cttatcttat cgggtatatg ggcattttta ttataggttt
    12181 atactcatat atccttactt ttatatacat atctttatga ttaaaggtgt tagaaaatgt
    12241 agtaaatttt atactatcag actctatctt tattacttta gtagatacat ggttgtaaag
    12301 gtttatagaa aaaaatatag gaaggcagat ttttattgtt gcgtatatat gagaatgata
    12361 taatatgaat attataaatt aataaattta aatttatgga ggtacaagag atgatggaat
    12421 ataaagttaa tgaccaagaa cttaatgctt caatgtttgt cccattcgtc aacaggatat
    12481 ggccaggaga ttatgatatg gataaaacac agactgcatt atcaaaaact ttgaatataa
    12541 ctgcttatga tgataaagtg cttgtaggat gtctgcgagt tctttcagat ggttattatt
    12601 ttggaacaat tacagaattg cttgttcttc cagagtatca gaaacaaggc attggtagta
    12661 agcttttcca gcttgctaaa gagaacaccc caactatgct atattttggt gcacagccag
    12721 gagtagaagc gttctatgaa aaaaatgggt gccaaagaag tctgcaatcc tacataataa
    12781 aaaagaaaga tagttattaa agttccagct ttcaataatc ttaaaagtac aatattttag
    12841 tggaatcatt tcatttttta ttactaatat gacataaaca tgtcatatta gtattgatat
    12901 acttttaata tggttaagag ccaaagaaaa atataaggag tgatttaaaa tggaagaaac
    12961 taaattttgc caatgctgtg caatgccaat gggacaaact gatgaattat atgggacaaa
    13021 taaagatgga agtaaaagta ctgattattg tagttattgt tttaaagatg gtgagtttac
    13081 agctgatata agtatggaag agatgataga agtttgtatc cctcatatgc ttcaaagtaa
    13141 taaggatatg actgaagatg aagcaagaac aatgatgaac aatttctttc caacattaaa
    13201 acgctggaaa taattttatg caaaattagt tatatgcaaa acatgaaata tggtgttgag
    13261 aataaggggt ggtgtgcttt atagcatacc acctgttttg ttacttgcta gttcagttat
    13321 tcttgtatgc ttaaatatgt tctcatccct ctttctattt caaattgtga aaatctaaaa
    13381 tatgttattt atattctact tctatatcca tgtcttttta tacctcaagt caaatccaac
    13441 tacaaaatca ttattttcaa ttctctgttt aactattaac agataaagaa ttataaaatt
    13501 ttctattttt tatataaaat aatacaggtc aagctgattt ctagctattt gagatagaaa
    13561 gagggatgag agttatagga gtaataccaa tcattagact gttgatttgt gtagtctttt
    13621 gtaaaaacat ttgttttaat atattgagtt tttgaaaaag taaaattata attaaaataa
    13681 attaagtgta ataatgtatt agaagtaaaa ataattaaaa tagaggtgat taaatgagta
    13741 gtatattgtt agttgaagat gatttaagct tgatatatgg attagagttc tctatacaaa
    13801 aaagtggatt tagtatagac atagcaagga cagtaaaaga agctatgcaa atgtatgagg
    13861 aaaaaaatta tgacttattg cttttagatg tatccctacc tgatggtaat ggatttcaga
    13921 tttgcgaaaa agtacgagag gtttctaata tacccattat atttttgact gcttcagatg
    13981 aagaggtaaa tgtagtgatg gggcttgata tgggtggcga cgattatata acaaaacctt
    14041 ttaaattaaa tgaattaatt tcaagaataa aagcattact tagacgttat aatgttgcaa
    14101 gtaatgtgaa tgaattaagt tcaaataata ttactattaa attacttgaa aatcgtgttt
    14161 ttaaaggtga atttgaggtg gaacttacca cagcagaata taaattattg tgcttattta
    14221 tgaaaaataa aaatattgta cttactagaa aaaacatatt ggacaagtta tgggatggaa
    14281 atggtagctt tatagatgac aatacattat cagtatatgt aagacgattg agaaataaaa
    14341 ttgaagataa tcctgaaaac cctaagtttc tattgaccgt tagaagaatg ggttataaat
    14401 ggaatgtaat taagtgaggg tattaatatg aagatatttt ctaataaaga tataaaaatg
    14461 ttttttttaa ttcttatatc tattttagta atgtttatta tagtagggca aatagtgctt
    14521 ataagtataa ctaacaatta taaaaaaacg ttgatagaac atgattataa tatagctgga
    14581 tacttatata gtataggtgt tgataaatct aaaataccat cagcatttgt tgtacatgaa
    14641 gataaatata ttttaaaagg aaaagaaata ctagatacag ctggatatgg atttgatata
    14701 gatgttagct ttacaccaag tgtaaaattg tttcaaagta aatatataaa aactatgtct
    14761 atctatttat tagtattttt tactatgatt attttcatac catatatgta tttttttagg
    14821 caacaaagta agatagaaga ggctagttat aaaattgatt catttatgaa tggaaatata
    14881 aatgaaagac taaatacata tgaagaaggt agcttatcaa aattatttag ttcaatagat
    14941 gttatgtcga catctttaaa tacacatata ttaaaagaaa aacagagcag agaatttctt
    15001 aaaaatacaa tttcggatat atcgcatcaa ttaaaaactc cacttacagc tttaataatg
    15061 tacaatcaga tactacaaga agaaagtcat aatagtgatg ttgttgaagc ttttgtacaa
    15121 aaaagtcaaa gtgaactaga acgcattgaa acattgatta agaatttact aaagattaca
    15181 aagatagatt caaaaacaat agttctcaat aaaaataatg ttaatcttaa aaatttaatt
    15241 gtcaaaattt tgtatagctt tgaaactagg gcagaaaaag aaggaaaggt tatttctata
    15301 aagggttcag aaaatacatt gttgttctgc gattatgaat ggatgtcaga ggctttaagt
    15361 aatcttataa agaatgcatt agataataca aaagagaatg ataaaataac gatagagtgg
    15421 tttgagacga ctataaccac cattgtttca gttaaagaca ctggaaatgg aatccatgtt
    15481 gaggatattc atcatatatt taaaaggttt tatagaagta agttttcaaa agataatcaa
    15541 ggtttaggac tgggattacc actagttaaa tctattgtgg aacaacataa tggtactatt
    15601 tctgtagaaa gtaaactatc acaaggaagt acattcacca taagtttttt aaagcttact
    15661 aatatgtaag ataaaataca tcttgcagta aggtatatag attattatta tattaatcaa
    15721 ttagaaaggt gagagagaaa atggatattc ttgtggttaa taatttatgt aaaacatatg
    15781 gaaatggata tacaaaagta gaggcattga aagatgtatc ctttacagtt tcaaaaggag
    15841 agtttgtgac tgtagttgga gaatctggtt caggaaagag tacactatta aatctcttag
    15901 gaggtcttga tactccaaca tcagggagaa tatttattga tggtaaagaa atatgttcaa
    15961 tgaaagagga aaaacagact atttttagac gtcgtaacat agggtttata tttcaggcat
    16021 ataaccttat accagaacta actgtggagc aaaatataat attcccattg ttattagatt
    16081 ataaaaaacc agatactatt tacttagatg aagtattgac tattttaggt cttaaagata
    16141 ggaaaaatca tcttccaaat caattatctg gtggtcaaca acagagagtt gcaattggaa
    16201 gggctttgat tacaaagcca agtattatac tggcagatga gccaacggga aatcttgaca
    16261 gtaaaaatag taatgatgta atttcacttt taaaagtgac tgcagaaaag tataatcaaa
    16321 ccattattat gataactcat aatacgaata tagcttctac agcagataga atactacagg
    16381 tttctgatgg tgtgcttaca gacctggggg tgaatagaga atgagaagct acttagaatt
    16441 agtaccacaa tatgcaaaag tacataagaa aaaaaataga actacaattt tatgtattat
    16501 tattgcagta tgcttagtta ctgctatctt tggacttgca gatatggcta tacaatgtca
    16561 aaagatacaa tttattaaag atgatggaaa ttggcacata gtaattagaa atattgatga
    16621 aaagtttata tcagaaataa atagtagagt agatatagct caccatggta gggggcaagt
    16681 cgttgacagt ggagagttta aatcaaagga gattttgata caaggtttag atgaagaagt
    16741 agcaaaacaa tttaacttag aaataataag gggtcgttat cctattgggg agaatgagac
    16801 tttaatagat gaggatgcag ttaaaagctt taatctaaaa ataggagatt ttatcaaaat
    16861 aaaattagca gatggtagaa ataaaaatta taagatagta ggtgaatatt catcaatatc
    16921 aagcttaaga gctacagata aacatggatt aatactttca atattgggta cacaagctat
    16981 taaaaaatca gaaacgtacg attattatta tattacattt aaagaaaagg ttaatattag
    17041 aaaagccact tctgatatta aaaatacctt caatttaagt gataaacaaa tcggtaaaaa
    17101 tgaaagatta ctttctatta taggtcaagg tgactctgac ttttctaaac cactgtattt
    17161 aacagcagga ttactttttg tacttgtttt agtagcaagt attatcatga tatataatag
    17221 ttttaacatg agtgtaattg agagagttaa attttttggt ttgttacgtt gtctagggtc
    17281 atcaaaacat caagttaaaa aatttgttgt tttagaaagt ttaattttaa gtataaaagc
    17341 tattccaata ggcttagtat taggaagtct tgtaactatt atatcttcta tatttcttaa
    17401 gtatgttaat gagttattca gctcaatgcc aattttaaaa gttagtttta ttggtattgc
    17461 atttggaata attgtagggt ttttaactgt aatattatca gctattattc cagcaaaaaa
    17521 agcttcccgt gtatctccac ttagcgctgt acgtgggaat ctaatgtcca aagaaatttt
    17581 aaataacgga aagacaagta aagttgcaaa tacaggaagt tttaaaattg agacttctat
    17641 gggattaaat catgcttttt caagaaagaa atcttttgta cttatgactt cttcatttgc
    17701 cattagtatt atactatttt taggttttag tgtgcttata gaccttatgt atcaaggact
    17761 taagcctatg aagcaagaag ctcctcatat atctattgtt gaccctaatt ttaagtctgt
    17821 tttaactaag gaagatatta atgaaataag taatatcaaa ggagtaaaga aagtatacag
    17881 tagaatgatg acggatatag aagctacata taatgggaag aagacaaaat cacaattaat
    17941 ttcttatgaa aagtatcaat ttaattgggc aaaaaaatat ctattaaaag gagaagttaa
    18001 tgaaaataaa ctacagtcag aaaaccttgc attagtagaa gaggggcatg gatttgatat
    18061 aggagataag atatatatta aaaatggaaa tgctgaaaaa gagttagagg taggaggtat
    18121 actttcctca attccatttg aggttaaaga taaatatatt ggaaatatta taacatctga
    18181 aaatactttt acgaatataa caggtataaa gggttatata ataatggaca ttcaggttga
    18241 taaagatact tctggagatt taattgaaaa tataagacgt gtagtagatg ataacttaga
    18301 ggtcagagat aaaagacaaa gtaacttaga ggttaaaaat tcgttttata ctatggcaac
    18361 atttgtatat ggatttgtgt ttattattgc gattataagc atgtttaata tcataaatag
    18421 catgaatata agtgttacaa gtagaaagaa ttactatggt gttatgcgtg cagtaggcat
    18481 atccaacaga caattaagaa gaatggtaat agtagaggca ggttcatatg cagtgagtgg
    18541 ttgtttatta ggtagtatac taggattaat gttacatagg tatatgttta tatcgttagt
    18601 aagctcaatg tttcatttag agtggcaagt accttttaat ttactactta tcactgtact
    18661 aactatgata ataataactt tattatcagt aagaaaacca gtcaaaaaga tttgtgaatt
    18721 agatataata gactcaataa atgcacaata aatatagcta ttgatttaaa ttaaaaaaac
    18781 aaagtaaaaa tgaaatagaa aatatttttc atttttactt cgttttttat attgtaaaat
    18841 ttttgttatg ttacaaaatt tctataaaga tgatgtgaat ctaaacatta tatgacaacg
    18901 tgagcattta agttaaaata ttttaaatat actattttag ataagttcct tcttcatctt
    18961 gataaattaa tccttttttc ataagcactc caagagctcg tttaaaattt ttcttacttg
    19021 aattaaataa tatagaaata tctttagggt cagacttatc attaaatctc atatatccat
    19081 cagaaccctc taaataactt aaaattttat tttctaaagt atcaagttca tcctttctat
    19141 ttcctctagg agaaagacca agttttccat cttcatatat ttttatgaca tgtaaatttt
    19201 caagaacatc accagttttt agttcagtaa agtactcatt atgaagtatt acaccagcat
    19261 atttgttgtc tacacatatc attgcagaat tattagtttg gaatccatat acaactccag
    19321 ttacaatatc tcctacattg taagtatggt ctgttaataa gtatgaatct atatctgtag
    19381 tagcagcaat tcttttgctt ttgtctaaat atatataaaa taaatatttt tcgtctctaa
    19441 atagtggata agtcttagct ttaaaaggaa ctagtatatc tttaggaagt cccatatcta
    19501 taaaagtacc aatgtctgta ttatcaacta cttttaagcg tgctacatcc ccaaccttag
    19561 ctaaaggcgg tattaaagtt gcagcagttc tgtcatcaga atctttaaat atgaaagcat
    19621 ttacttcatc acctatgttt atttcatttt ttccgattaa tctattatga agaagtatat
    19681 catcttttgt gttattagtt tgtccatcca aaaaatatcc aaattcagtt tttcttttta
    19741 ctgtaagttt attaaaatca cctatgttta tcaaattaaa atcatcctct cattttatgt
    19801 ttataattta gccataatat acttatgtag tagtttgtca cagtatctat attagtatta
    19861 gtgaaattta caataaataa tatagttatt tatgtatttt tcaattctct agcttcttat
    19921 atagtataaa ctccaatttc ttttttgtct ttaggtttta ctaaaatttt tacaaaataa
    19981 attaaaaagt attgaaataa aatttctttt aaagtataat tggtatatac caaaattggt
    20041 atataccata ttgaaaagtg gtgattaata tgaaaatagt aaataaatct agtaacatac
    20101 cattgcatac tcaattaagt tcaataataa gagagatgat agaaactggt gagcttaaag
    20161 aaggtgatgc aataatgcca gaaagagaac tttgtaacat acaaaatgta agtcgtatga
    20221 cagtaaataa aactattgtt ggattagtaa cagaaggact tctttatagg gtacaaggta
    20281 aagggacatt cgttgcaaag caaaaaaaga agtatcagtt ttcaaatgta aaaggtttta
    20341 ctgatgttat gaaagaaaag ggagtaaaca taaaaacaga tatattatcc tttgagatgg
    20401 aactaccaga tgatttagtt aaaagaaagc ttggaataag tgataatact acaaatatat
    20461 ataagattgt cagacttaga tatactgacg gagagccatt tggattagaa atagtatatc
    20521 tatcagaaga aatgtgtaag ggtctaacaa aagggatatt ggataattct tcattatata
    20581 gggttttaaa tgaaaaatat ggctataaga tacaaaaagc tgaacaggta atggagccag
    20641 taatactttc agatgaagaa agtaagcttc ttgaaacaga tgaaggtgct ttagctctta
    20701 aacttcatag aaattcctat aatagagaag gtaaccctat agaatatacc atatcaatat
    20761 ttagaacaga taaatatcaa tatgaaatag tattgagtga gtaggtgaat aatatgaaat
    20821 gtttaattaa tggaaagata atattaaaaa atcaaatctt ggaaaataaa gtactagtat
    20881 ttgatgaaaa aataattgat atagctgata gtgtaccaaa agattgtgaa gttatagatg
    20941 ctgatggaaa atatatatct ccagggctta ttgatattca tatacatgga aacatgggaa
    21001 aagatacaat ggattcaact gatgaatcta ttgaaacaat ttcaaagtca ataatgagac
    21061 atggagtaac atcttttctt ccaactacaa tgactatgga taaagaacat gtttatgatg
    21121 cacttgaagt tattaaaaaa gcccaaaata gaaagcttga aggggcacaa gtattaggag
    21181 cacatttaga aggacctttt ataaatgaga attataaggg agcacaaaat gaaaagttta
    21241 taataaactc aaaatacgaa tttataaaag aatataaaga tgttataaaa gttataactt
    21301 atgctccaga aaaagatatt gattttgatt ttactagaga aataaaaaga tgtacagata
    21361 tagttttatc tattggtcat agtaatgcaa attatgagca agctaaagaa gctataaatt
    21421 taggtgtaac aaatgtaact catatgttca atgcaatgac tggtttaaac cacagagacc
    21481 caggcgttgt tggtgcagca cttacaacta atgtgtacag tgaactaata gcagatacaa
    21541 tccatataaa taaagattta tttcaattta tactaaacaa taaaggtaaa gaaagattga
    21601 ttttaataac agattctata gaagctggtg gtcttgaaga tggagattat tctcttggag
    21661 gtcagaaagt catagttaag gggaatgaag ctagacttga aaatggagca ttagctggaa
    21721 gtgtgttgtc tttaaataaa atggtattta acttcttaga taatacaaac cttaaggtga
    21781 atgaagcgat tagtttagca tctttaaatc cagcaacatc tttgggaata aatgacaaaa
    21841 aaggaagctt agaaataggc aaggatgcag atatagctgt atttgatgag aatttagatt
    21901 gtaaaatgac actttgcttg ggggaagtag tatataaaaa tatatagtat acagaacaaa
    21961 ctttaaagac agtaaaagca atataaaaaa taataaatta aacttacctt agttgaaata
    22021 gtagttaaaa tttaggagga acaagatgag agtattagtg tgtaaagatt atgatgcaat
    22081 gagtaaaaaa gcagctgaga tgatagcagc tcaaatagtt ttaaaaccaa attcaatatt
    22141 aggactagct acaggaagta caccagtagg tatgtataga gatttggtaa aaaaatacaa
    22201 tgataatata gtagattttt cagatgtgat gagctttaat ttggatgaat attataagtt
    22261 accaatatct aatgaccaaa gttatgatta ttttatgaaa gagaatctat ttaatcatgt
    22321 aaacataaag ccagaaaata ctcatttacc aaatggaatg gctgatgata ttgaaaaaga
    22381 gtgtatgaac tatgaagctt ctatagatgc agctggtggt atagatgtac aagtacttgg
    22441 aataggtcgt aatgctcata taggttttaa tgaacctgat actaaatttg caaaaagaac
    22501 tcatgtagtt gaacttacag aatctacaat agaagctaat gcaagattct ttaaatcaag
    22561 agaagatgtt cctaaaaagg ctgtaagtat gggaataggt tcaatattaa aatctaagaa
    22621 aatattactt ttagcttcag gagaagaaaa agctgatgcg gtatataaga ctgtttatgg
    22681 agagataact ccagaagttc ctggttctat acttcaactt cataaggata ctatagttat
    22741 agtagatgaa gcagcagcaa gtaaattgaa tccaaacgat tataaattag tataataata
    22801 gaatgtagtt taagtaaaaa atagctatca ttgaataatc aaatttattt aatgatagct
    22861 attattattt aaatcactta ctttttttca tttaaattag ttattattgt ttaaattact
    22921 tgtttattac tttttacgaa aactcgttat caagaagtat ccaaataaga tgttaaaaat
    22981 tattatactc agtgggattc tatcaagtat aataaaatta cctataatcg gaatattacc
    23041 aactggaaac ataaagaaga atacaggcat caatgatagt aaaaaagatg gaaaacaaag
    23101 aagaagtaat cttgggatat caatatacca actaccactt tttttgtatt caccaatcaa
    23161 taattcagtt cctagtaata aaccaatacc accagaggaa attaggttaa taaaaatata
    23221 tcttttaaag tcttgcatat aaccagtgtg aaatcggaaa taaaaatcat aatttaattt
    23281 aacagctaag aaatacataa gcaatagaat aattaaaaat aaaaaatatc taagagtttt
    23341 tttcatttta aattctccct tcagaaatac tttatccagt tttattttgt tggaatatga
    23401 ttttatcatt tagtttaaga aatccataat attagtgaag aatgaaaaaa gtactatata
    23461 tgaataaata tttttagaat taaggtgaac tgtagtactt aatataacta taatattaat
    23521 tgtttgaata ttcaataaaa agtttgaaaa atatcaattt tgatataaaa tgaataaata
    23581 cagttgaata ttgaattatt attttatcaa aaatatgcaa agtactacac tttcaaatgt
    23641 cacctaaagt aataaaaggt aattaaagtg aagtagttca agatatttct aaaatgagtt
    23701 taataaattc tataataatt tattttttgc cttaaaattg ccttaaaatc caaacaattt
    23761 taaaactaat gtactataaa aagctggtat aatttaaata tagtaaaaaa taagatttat
    23821 cttatctatt gggattcaat tatttaatca atatatttat actatttaat ttaaataaaa
    23881 agtctattaa ggagtgagct tatgagtaaa ttaatttata tagcagatga tgaagataat
    23941 ataagaaatt tggtaaagac attcttgaaa aatgaaggtc atgatgttat ggattttaaa
    24001 acgggtgatg aacttttaga acaatttaat ataaaagagt gtgacttagt aatactagat
    24061 ataatgatgc ctggttcaag tggttttgaa gtatgtacaa aacttcgtga gaaaagtaca
    24121 gtcccaataa tcatgcttac tgcaagagat acagatatag attatattac agggataacc
    24181 ttaggtagtg atgattattt tacaaaacca tttagcccaa tgtctttggt tatgagagta
    24241 aaatctatat ttagaaggat agagtttgaa aaaaaacaaa attatgataa atatagtaac
    24301 ttggtaaata tggaattaaa atttggggat gtaataataa ataaaaagaa taaaatcgtt
    24361 acaagtaaaa atgtaaatat agaccttaca ccaaatgaat ataacctatt gacttatttg
    24421 tttgaaaata tagatagagc agtttcaaga gatgaattat taaacaaagt atggggatac
    24481 gatatagaag ttgagacaag ggctgctgat gatacagtga agagattacg taaaaaaatt
    24541 ttagatacaa atattttaat agaaactgta tgggggtttg gatttaggtt gaaggagaaa
    24601 agttaagatg aagaatggaa atgacaagaa tataattgga aagattaaat ccaaatttaa
    24661 attaaagttc tcaaagaaaa atataagcat aaaaactagg attttgttga gcatactttg
    24721 tttgataatt atagtattta tgataatatt agtatctttt aatgtatttc ttgatacata
    24781 tataaaaaca actgcgaatg aagaattaac aaagtctaca gaaacagtag aacatatgga
    24841 tagtaatttt agacctatta agccaccaca agatgatgga aagcttcctc ccaaagtatt
    24901 atctaatttt atgagaaatg tacaagataa agttaggatg gcagaaacac aatcagatgc
    24961 tgatgctatg gtagttgatt ctaagtataa cctgatattt ccaacaagag agaatgattt
    25021 cttaaaaaat gttgatgaga tggagctgat tagggagtgt attcaaaatg aaaaattaga
    25081 tttaaattca gatgaaaata cacggatatc taccagaaat aaggattatt atatttcaac
    25141 tgtaaaaatt actagtatat atggtgaaca agacaagtat cttgtacttt ttatagacat
    25201 atcaaaaact ctaaatctag cacaaaagat aaatattgta ttaatatctg taatgtgttt
    25261 tgctggaata ttagcaatat ttacagctgt gattttatct gagaaaattg ctaaaccgat
    25321 aaaagagttg tgtgaatttg caaaaaaaat gggtcaagga gatttcaaaa gaacttactt
    25381 tgatttttca gataaagaat tagtagagct ttcaaatgtt atgaataaga gtgctgagta
    25441 tctggataag tatgataatg agcaaaaaat attttttcaa aatgcatctc atgaattaag
    25501 gacgccactc atgtctatta aaggttatgc agaagctata aaatataatg ttatagatag
    25561 taagtatgca agtgatataa ttcttgaaga aagtgatagg ttaagtgata tggttgaaga
    25621 tttattatac atttccaaaa tagataatat aactaaagat tttgaacttg tagaatgtga
    25681 tttaagagaa gtactttcaa attgtggagc taggcaaaat gtaagagcta taaacaaggg
    25741 tataaaattt atttatgaat ttgatgaaaa aatggtttta tttgaatgtg atgaaaaaaa
    25801 tatttccaaa gcatttatga atcttataga aaatgctttg agatacgcta agagtgaaat
    25861 aaaaatagtc tgtaagcata accaaaaaaa tatagttgtg atagtagaag atgatggaat
    25921 tggaattaag aaagaagatt tgcctcatgt ttttgaaaga ttttataagg gagtaggggg
    25981 aaatcatgga attggattat caatagttaa atctattata aataagcatg gtggacgtat
    26041 atacgtagaa aatggcaaaa aaggagctaa gtttactata ttatttaaat tgtaaaaaaa
    26101 ttagagaaaa tatagagatg tttgaagttg ttttttatat atatctgttg tatactgttg
    26161 aaaaaagaac aatattaagc tgacatatat tataataatt gacatttaaa gtaaatgctt
    26221 aaatatagat acgaaaggaa aagtaaaatc tgaagtgcat ttaggtttaa gtaaacttct
    26281 tattttataa aaaatatgta tgaaagaaca gctgattttt aatattacaa atttagtaac
    26341 agttgtattt gaagcttttg tcatccatat gtttttatca gactttttag gtcagaaaga
    26401 agggtatata aaagttgtaa gatatgctaa attgggtttt ataatatgtt taggactttg
    26461 taatttaata actttaaacc ctaaaattac aatgccttta attttcattc ttattttttc
    26521 aacatcattt ttatataaag gaaatttaaa gacacgattg tttacgactg ttttattaag
    26581 tatatttttt atactgtcag aaattgtagt tacaagtatt tttgttttat ttataaaaga
    26641 aggctttgaa ataatgtttg aaaataatag tataagagta ttggcgacaa ttttatctaa
    26701 aattgtcttt ttgttgactt gtaaaattat ttgtctattc aaaaaagatg tacatttaga
    26761 tatgcccata aagtattggt ttcctttatt tttaatacct atatttagtt tatttctgtc
    26821 tgtttctgtc tttgatgtaa gtaaattttt tagtcttgaa tgtttaaaat ttctgagctt
    26881 aatatctagt attggtattt tgtatattaa ttttattgtc ttttatttat ttaaatttat
    26941 tatagataaa actaaactat ctatgaaata tgaaatactt gaaaaagaaa taattcataa
    27001 ggaagaatta agacttagta atgagcgtta taaaattatt gttgaacaga ccgattctgt
    27061 tgtttttgaa tggaatatca aagaaaacaa atcgtttgta tcacaggctt ggaatgaaaa
    27121 atttggatat aataatgtat gtaagaatat ttttaaagaa attaaagata aagacttagt
    27181 tcattctgaa gataatgcta tatttgaaaa ttttcttgaa agtattaaaa aaaagaatag
    27241 acacaatcaa gcagtatatc gtttaaaaaa atctaatggt gaatatattt ggtgtagaac
    27301 atcaattaca agtatttata atgatgaaaa tgagctttta agagttgtcg gagtaattgt
    27361 agatgtagat agtgatataa aaaaatatga agagttaaaa actagagcag aaagtgattc
    27421 attgaccaat atatacaata aaggtacatt tgaaaaattg gtagaagaaa ctatagttat
    27481 gaatacaggt gataaaaaag atgcattatt catcattgat ttagatgatt ttaaagaaat
    27541 aaatgataat tttggtcatc catttggtga ttttgtactg aaaacctttg ctgataagat
    27601 acaggctagt tttggtagta gagacttagt cggaagaatt ggtggagatg aatttgtagt
    27661 atatatgcaa gattacgtta cagaagtaaa tttgcacaaa aaagccaaag agttaaatag
    27721 agtactttcg gataattaca ctgatttgag ttttagtttt gatgcttctg tcagtatagg
    27781 tattgcaagg tatcctcaag atggaacttc attttttgaa ttgtttaaaa atgcagatag
    27841 agcactttat agcataaaag catcaggtaa aaattcatat tgtttatttg aagaagagct
    27901 atatgtacag tgaatttaga ttttatgtga tatcaagatt tatatatgct tgtggcatgt
    27961 ctaatttata aaatatgtta ctatgtatgt ttttatatgt ttcagtgagg ttaattaata
    28021 taagcaaagg tgtaagtaaa tttatattaa tgtaagttta tttacacctt tttaaaaata
    28081 aattttgtaa atttaaacag ttaattttat aattattttt atttatttta atatcttagc
    28141 tgttcctttt tgtattcctt agagaaaata aacaatgaaa ggagtacaga aaaaattaaa
    28201 catcctaata taatacttga attaagactt gaagcattaa aatttaaaaa tgcattattt
    28261 aaatcggtat ccaaaagaac agtattatta attaaatgaa ttactacaca tgaccatacg
    28321 tttttagttt tcatatagac ataaccaaag aatatagaaa gactaatcac agaaaataat
    28381 ctaagtaata tacctaaaac atctacatga taaactgtaa accataatgg tatgtgccat
    28441 aattcccata taatccctaa taatataacg cccattcgtt tgccaaattt tgtttgcatt
    28501 ttttcttgaa gaaaacctct ccacccgtat tcttctccaa agaaaaggat actttgattt
    28561 gctatatatg gaaaaattaa aaatatattc ataatcaaat ttataaaatt aatatctttc
    28621 catcctaaca ttatacattt acttagatta attattatta taaaaataaa aatacaaata
    28681 atagatttat ttacattctt aaatgggtaa agctctttgc cttctaaaca tgcataacat
    28741 atcgttataa ttccagtaaa taagactaaa atacccattc ctaagagtat agtttcatca
    28801 tctattactc caaatgcttt taaagtaact agaaatagag ataataaaaa gtcagctatt
    28861 ataacacagt gaagtataat atgttcatca ctctttttat gtttataaat ctttgttatt
    28921 gcaactcctg atgctggtaa tatagtcata aatgttacca ttatttgtgg attcatatat
    28981 tttttaaaat atagaggtat cccaaataga agtgatatac cataagttac tacaaaaaat
    29041 attataactt ctaaagtatt tattttttta tcactatttc tatcagctat ttcgcattgt
    29101 atcataataa tttatctcct ttcagatttt aacttctgct gagatttgag ttagatattc
    29161 attagaatct cgcacactta tatcatatag aagatattct tcataaacaa aatccccaat
    29221 acataaatta ttttgactaa aaaaatttaa taacttttca taagtcttgt aaatagtttc
    29281 ataactacct ttatgataag cagttacata aagccctttt tgcttgattg atacaggata
    29341 tttcttgtac tctttattaa cttttgtaaa taaatatgaa tatgattcaa aatctttatt
    29401 aattatatct tcacctttaa tgattgagcc aatcatacca taatcactca attcatagtt
    29461 gtctataaag ttaatacatt catataaaaa attttcttcc tcatctccta aaaactgttc
    29521 tttatatgta atgggcgttt tgaccaagta ctcttcttca tgttctttta aagtaatagt
    29581 atttgcatct atattacagg catttttagt aaatgaaata gtagattcca ttagagcttg
    29641 aatattattt agtttttcaa tttcattttt aatatcaata gttttctttt ctaaaagttc
    29701 aattagtaaa ttaggtgttc ttttgtctat ataagtttta atttctttta aaggcatttt
    29761 tatttcctta agtgaagaaa ttataccaaa aatgctaagc tgatggtatg agtagtatct
    29821 atatccattt tctttcttta attctggaga gaaaagacct atatcatcat aatggaaaag
    29881 tgttttttta ttgactccac aaatctttgc aaattctcca gttgtaaaat aattttttgg
    29941 aacttgactc ataattataa ttcctccttg actatcctgt tacagtatag tttatcataa
    30001 tattttgtaa aggagtgtga ttgtatgaaa aaattaattc attttttaaa accatataga
    30061 gttttaattg ttgtagtttt gatatttacg tttttacaaa cacttggaac tttgtatata
    30121 ccaacactta cagcaaatat agtaaacaat ggcatagtaa agggagatat agattatatt
    30181 gtaaaaacag gtttaatgat gattatagta gctggtataa cagctttatc agctgtgtta
    30241 gtttgtaaag tatcagcaaa tctttcatct ggattttgta gagatattag agaagcagta
    30301 tttataaaat cacaagattt atcaataaat gattttaata atataggtac agcatcaatg
    30361 attactagga gtactagtga cattacttta ataggtcagt ctgtatttat gttcattcaa
    30421 ttagtattgc cagcaccaat tataactgtt tctggcctgt tcttagctta ttctatagat
    30481 aaagtaatga caattattat tgttgttgta atgtttctat tcatgttatc agcattttta
    30541 gttggtaaaa ggcttattag attgtttaag attatgcaaa taaagatgga taatatgaat
    30601 agggtattgc gtgaggtagt aactggagta agagttataa gagcttttaa tagaagtcat
    30661 tttgaaaaaa agagatttga taaaactgca atagattatt ctgaaacagc aatttcaata
    30721 aataaagtat tttcagtact tatgcctatt gtaatgttaa taatgaattt aggtatagta
    30781 agtattattt ggtttggtgg tatgagagtc agtaatggaa atatggagat aggtcatata
    30841 atggcacttg ttgaatattg tatattaatt ttattctact taatcatggg agtaatggta
    30901 tttatgtaca tacctagagc aggtgcctgt gcagatagag taaatcaaat attagatata
    30961 gaacctgaaa ttgtagatgg aaatgtctac aaagatgatg tctcagaaag aggacattta
    31021 gtatttaaaa atgtaacctt ttcatatgct caatcagaag aacctgtttt aaataatata
    31081 acatttgaag caaagtctgg agaagtaact gcaattatag gaagcactgg ctcaggcaaa
    31141 tctactattg caaatataat accacgtttt tttgaaattc aatctggaga aatctctcta
    31201 aatggtcagg atattaagaa gattcctcaa aaagaactta gagataagat tgggtttgta
    31261 ccacaaaaag cttttttatt tagtgggaca atagaagaaa atataaggta tggaaaagaa
    31321 gatgcaagta ttgaagaagt aaagcatgct gcaagtatag ctcaagctga tgaatttatt
    31381 tctgatatgg aagacaagta tgactcattt gtagcacaag gtggaaataa tttgtcaggt
    31441 ggtcaaaaac agagaatatc cattgcaaga gcattagtta gaaagcctga agtatatgtc
    31501 tttgatgata gtttttctgc actagatttt aagacagata aaagacttag aaaagcgtta
    31561 aagaatgaaa tcaaagattc atcagctata attatagcac agcgtataag tacaatcatg
    31621 gatgctaatc aaattatagt tttgaatgat ggaaaaattg tcggtattgg aaaacataaa
    31681 gatttacttg aaaattgtga agtttataag caaattgcag attcacaact tagtaaagaa
    31741 gagcttgcat aggataggga attaatctgt gtatttggag gtgtgtaata tgagtgaaaa
    31801 aagaacagat aaacaagata tagaggtact tagttttgaa gatggtatgt cagcagaaaa
    31861 agctaaggat gcaaaaaaaa ctactaagag attattaaaa tatatggcaa aacaaaagtt
    31921 taaaatatta attattttta tttcagtatt gataagttca gcacttacag ttttagcacc
    31981 tatggttatg ggaaaagcta ttgaccaact atttaatgga ataaaaactg cagtccaaac
    32041 aggtacaaaa ttcagtgtga attttagtac tatgggaggt atagtatcaa tacttctagg
    32101 attgtacttg gttagtgcaa tatttatata tattcaacag tatattatgt caggagttgc
    32161 acaaaattta gttcttagca tgagaaaaga tttaagtgat aaactcaata aacttcctct
    32221 taagtactat gattctcata aaaaggggga aacacttagt atagtaacca atgatttaga
    32281 aaaagtagca gatagtttac aagaaggatt aatgcaactt attacagcag tagttacagt
    32341 agttggttct attgtaatga tgataagtat aagtgtacca cttacaatag tatcagctat
    32401 aacattactt gtttcattgg gtattactgt tgtaattgca agaaaatcac aagaaagatt
    32461 ctctgaaaat caaaaggcac taggagagtt aaatagcaat atagaagaga tatttactgg
    32521 tcaaatagtg gttaaagcat ttagtaaaga aaaggatact ataagaaact ttaaaatatt
    32581 aaatcaaaat ctttataatg caagtagaag agcacagttt tcgtcatatg caatatctcc
    32641 aattattaga tttataaacc taattggcta tgttattata gcagttgtag gtggtatatt
    32701 tgcatcaact ggagcaatga ctcttggtag tatacaagcg tttattcaat atgtaaatca
    32761 agcatcagag cctactacag aaatatctta tattgtaaat atgcttcaag cagcaatagc
    32821 atctgcagag agagttttta cagttatgga cgaggtagaa gaaataaagg atgaagaatc
    32881 ttcaaaggtt atcagcatgc ctagaggtaa agtacaattt gagcatgtta aatttggata
    32941 tagtgatgat tttattctta tgaaagatat taatatcaat ttaaatgcag gagataagat
    33001 tgcaattgtt gggcctacag gagctggaaa gacaactctt gtaaatttac ttatgagatt
    33061 ttatgagata caaggtggaa gaattactat tgatggtgtt aatataaaag acttaaagcg
    33121 tggagaactt agaactatgt ttggtatggt tcttcaagat acatggttgt ttaatggaag
    33181 tataaaagaa aatattgcat atagtaagtc agatgcaaca atggatgaaa ttgtaagagc
    33241 agcaaaatca gcaagagtag accattttat aaggacttta ccacaagggt atgacactat
    33301 attgactgag gatgcttcta atctatctca aggtcaaaag caacttctaa caattgccag
    33361 ggcaatactt tcagacccat cagtattgat tcttgatgaa gcaacatcta gtgtagatac
    33421 tagaacagag gtagaaattc aaaaggcaat gaataacttg atgaagggaa gaactagttt
    33481 tgttattgca catagattat caactattcg agatgctgat ttaatattag taatgaaaga
    33541 aggcactatt attgagcaag ggagtcatga ggaacttatt gaaaagaaag gattctatga
    33601 agaactttat aacagtcaat tttcaagtga atatgatgaa gatgttgtat gattatcaag
    33661 ttttaggcaa ctaaatgatt gataaatatt aagttaaata cagtaacata taaggttata
    33721 tggaataaga gtatttctct atttcatata acctttttta tttgtcaaaa taagataaaa
    33781 tttcctttct aaattagatt gaagaatgta tttatcaata taaaagtaaa ataaccctta
    33841 attagtgaag taaatattgc ttgccacata tatgccataa agatgcactt attttacgga
    33901 gatttaacaa attagcataa agtatactct aaatatagaa taaatcaaat agagttaaat
    33961 aaattgagag gtgatataaa taatggataa aaaattgaac tatagatttg aaatgaagca
    34021 caaaataact gaagcagatg tgctagcttt aaaatcaaga ctctatccaa tcatgaagaa
    34081 agataaaaat gcattaaaag atggaaagta tcttattaga agtttatact ttgatactcc
    34141 tgaggataaa gctcttttgg ataaattgaa tggcgttgca ttaagagaaa agttcaggat
    34201 aagattttat aataatgact gctcctatat aaggctagag aaaaaaatca aacattacaa
    34261 tatgacatca aagctatcag ctagtttaac taagacagaa gtgataaaga tattgaacaa
    34321 tgatattgaa tttctaaaag aatcgacaaa ttgtttatta agagaatttt atttgaaaat
    34381 aaaatgtgaa agattagagg caaagagtat agttgattat gatagagaag cctttgttta
    34441 tccagttgga aatgttaggg ttacaattga tagtgatatt aaaacttctg taaattcaat
    34501 agatttgttt aataaacatt taccaactgt ttcgataatt gatgagaaca tgacggtact
    34561 tgaggttaaa tatgatgaat ttataccaga ttttataaag gatttaattc aaattaataa
    34621 gactacttct acagcagttt caaagtatgc ttcaagtaga ttatatattt aataataaaa
    34681 gctatgattt atatgaagct atacataaat gaggttaaaa aataaataaa ataaaaaata
    34741 aattaaagat taggaaggat gattttaatt atgacattta acgatatttt taaatcaagt
    34801 tttatagaaa acgtatcagg tttttcattt gtggacagtg ctttagcact aggttcagcc
    34861 tttttagtag gtttgtttat atatatggtc tataaaaaga cttatatggg gattatgtat
    34921 tctcgaccat ttaatgtgtc gcttgtagca cttacaatgc ttacaacctt tgtaatattg
    34981 gcagttactt caaatgtagt tttatcttta ggtatggttg gtgctttatc tatagtaaga
    35041 tttagaacag caattaaaga cccaatggat ttagtatttc tattttggtc attgggttca
    35101 ggtatagttt taggagcagg tttaattcca ttagctgtca tgggttcaat aattatggga
    35161 ttgattctaa tattcttttc aaataaaaca atatctgaaa ctccatatat attgatggta
    35221 aactgtaata atgaagattc agaagatata gcaactgaca aaattaaaaa agcatttact
    35281 aaatatcaaa taaaatcaaa aagtgttaca ccagaaaaag gaatagaatt agtgtttgaa
    35341 ataagaatga aagatggaga gacaagtctt ataaatgact tgagtcaagt agatggagtt
    35401 actaatgccg ttcttgtaag ttataatggt gactatgtag catagagagg agtaatcttt
    35461 tatgaaagat aaaaaattta cccttcttat ctcaataatg attatatttt tatgtgctgt
    35521 agttggaatt tatagtacat ctggcaacaa aggtgttgat ttatacagtg atgtatatat
    35581 tgaaaaatat tttaacagag acaaggttat ggaagttaat atagagatag ctgaaagtga
    35641 tttaaaagac atgaatgaaa atgctataaa agaagaattt aaggttgcaa aagtaactat
    35701 agatggagat acatatggaa atgtaggtat aagaactaaa ggaaattcaa gtcttacgtc
    35761 tgtagtaaat agtgatagca atagatatag ttataagatt aattttgata agtacaatac
    35821 tagtcaaagt atggaagggc ttactcaatt aaatcttaat aactgctatt ctgacccatc
    35881 ttatatgaga gagtttttaa catatagtat ttgtgaggag atgggattgt ccactccaga
    35941 atttgcatat gctaaagtat ctataaatgg cgaatatcat ggtttgtatc tggcagtgga
    36001 aggattaaaa gaatcttatc ttgaaaataa ttttggagat gtaactggag acctatataa
    36061 atcagatgaa ggaagttcgt tacaatataa aggagatgac ccagaaaact actcaaatct
    36121 aattgttgaa agtgataaaa agacagctga ttggtctaaa ataacaaaac tattaaaatc
    36181 tttggataca ggtgaagata ttgaaaaata tcttgatgta gattctgtcc ttaaaaatat
    36241 agcgataaat acagctttat taaaccttga tagttatcaa ggaagttttg cccataacta
    36301 ttatttatat gagcaagatg gggtattttc catgttacca tgggatttta atatgtcatt
    36361 tggaggattt agtggttttg gtggaggtag tcaatctata gcaattgacg agccgacgac
    36421 aggtaattta gaagacagac ctctcatatc ttcactatta aaaaatgaga catacaaaac
    36481 aaaataccat aaatatctgg aagagatagt aactaaatac ttagattcag actatctaga
    36541 gaatatgaca acaaaattgt ataacctgat agcatcatat gtaaaagaag acccaacagc
    36601 attttatact tatgaggagt ttgaaaaaaa tataacgtct tcaattgaag attctagtga
    36661 taataaggga tttggtaata aagggtttga cagaaataac tctaataata attctggaaa
    36721 taaaagtgat gaaaaagaag ttactgctga attaacatta agtgaagtca aaactaatat
    36781 ggataatgaa actgagaata atactacagg tgatagtaaa aataagaata atacgaatga
    36841 tgataaaagt ggaaatggta ataatcaaaa gccagaaggt tctatgggta aaggaggaaa
    36901 gtcaatacca ggagttttgg aagttgcaaa agatatgagt aaaactataa aagctcaatt
    36961 aaatggagaa acttcttcaa caaagcaaaa ttctggtgat gaaagctcaa gtgaaaataa
    37021 agggactgaa aagtttgatg aggatgtggg tggtatgcca gaaccacctg agggaatgga
    37081 tggtaaaatg ccaccaggaa tgggaaatat ggataacggt gatatgaatg gtaaaaatgg
    37141 caatatgaat agaaatcaag gtaatccaag agaagctgga ggttttgaaa ataaaggagg
    37201 gggctctatg agtaaaacaa gaacatactc aaaattaatt ttaggtggag cttcaatgat
    37261 aattatgttg attatgttag taggtgtatc aaatataaat agaagaagat ttataaagtc
    37321 aaaataagat tgatattaaa aaatactgtt gagtagacat ctactcaaca gtatttttta
    37381 gatattaaga ttaaatttat ttagaaataa gagttagatt tttttactta aattgaaata
    37441 aaatatgcaa atagttttaa aatgtagaaa ttatttataa taatattaaa aaaaatttaa
    37501 ttgaataata ttaaaaaaat tgtaactaaa ttgtaataaa atggtagtta tttagcataa
    37561 aatgatgtat catagaagtg tattatttaa tagaaatctc cagatttaaa tatcacataa
    37621 gatagttaat gtggagtagt tcaagagaaa actgctggct ttcgatattt agagtgagta
    37681 gttaaattat gtttaggagg ggtagaattt gttgcaaaaa gtattatgga aatttttaaa
    37741 gctagtgttt ggtttattta tatgttcagt tggtatagta ttgacgataa attgtaacct
    37801 tggcttatct ccctgggatg tatttcatca aggactttca aatcatatag gaataactat
    37861 aggaactgcc tctataattg tgggttctat agtagttatt gctgatgtcg ttcttggaga
    37921 aaatgtagga tggggaactg tttttaacat gctactaatt ggatttttta tggatttact
    37981 tttatatagc aatttaattc cagaggctga tagtttattt gtaggaataa ttatgttgat
    38041 attaggatta attcttttgg ctgttggaat ggtcttttat atgggaagtg gtttaggaag
    38101 tggacctaga gatggtttga tggttgcact tcaaaagaaa acaggaaagt caattaactt
    38161 aataagaggt attatagaag ttggagcatt aatagtagga tttttattag gtggaaaagt
    38221 tggtatagga actataataa gtgcatttgg attggggtat tttacacaaa tggtatttgg
    38281 cttatttaaa ttagattgta gtaagattaa acatagattt atagtagatg atataaaatt
    38341 tatcaaagtg tatatgagtg gagagaaaaa agctgctact caaaatatag ttaagtaatt
    38401 taaaaataaa ttcaacgaaa tgttaggtat tttaaattaa aattttgttt agagatataa
    38461 actaaatatt aaaagaatat taaaatataa ggattgctag aacactataa aatatagatt
    38521 tctagcaatt ttttatttgt tcaatgtttt tttagtatta gaagtcttat tctctattta
    38581 atgaatgaat taatttataa ttagagatac taaactttat agatattaat ataaacacct
    38641 ttaaactgtg tattttccaa agcctttaaa atgcttgtat ttattctaaa taaaaaaata
    38701 aaaaaatgtc aaaaaaactc ttgtattata tccaaatttt atatataatt acctatgttg
    38761 tttagaaatt ttaaactcaa tgtttagtaa acaaaatgtt tagtaaaata aaacagaaac
    38821 taggaggtgc aacatggata taggtgaaaa gataaaaaga ttaagaacag aaaaacaact
    38881 gacccaggaa gagttagcta atagatgtga attgtcaaag ggatttattt ctcaattaga
    38941 aaataactta acatcaccat ccatagctac ccttatagat atacttgaaa tactaggtac
    39001 aaatttaagg gaatttttta atgaaataga tgatgaaaga atcagtttta caaaagaaga
    39061 tatgtttgaa actgaagatg aagacttaaa atataaatta aagtggttaa ttccaaattc
    39121 acaaaaaaat gaaatggagc caataataat aacattgtat ccaggaggac agtataaaga
    39181 agaaaagcca cacgaaggtg aagaatttgg atatgtatta gcaggttcaa tatacgtcca
    39241 tataggcgaa aagaaaaata aagtaaaaaa aggagagagt ttttacttta gaccgaaagc
    39301 aaatcactat atatcaaacg aaggcaaaac tacagcaaaa gtgatttggg taagtacgcc
    39361 accatcattt tagaatagag gtgtttaata attggtagaa aatataatag aattaaggga
    39421 tatatctaaa cattatgagg aacttactgt tttagataat ttcaatttag atataaagaa
    39481 aaatgagttt ttaacattac ttggaccaag tggatgtgga aaaactacaa cattaaaaat
    39541 aatagcaggg tttgagtatg ctgatgatgg taaagtttta tttgaaggta aggagataaa
    39601 taatttgcca ccatatgaaa gacaagtaaa cacagtattt caaaaatatg ctttatttcc
    39661 acacatggat gtttatgaaa acgtagcttt tggactaaaa attaaaaaga ctccaaaaga
    39721 tgtaatagat gctaaagtaa aagaggtttt gaaacttgtt gcactagaag gttttgaaag
    39781 acgacaagtt gaatcattga gtggaggaca acaacagaga attgcaatag caagagctct
    39841 agtcaatgaa ccaaaagtat tgttactaga tgaaccactt ggagcacttg atttaaaatt
    39901 aagacaagag atgcaaatag aattaaagag aatccaaaaa aaattaggaa taacatttgt
    39961 gtttgtaact catgaccaag aagaggctct tactatgtca gatactattg ttgtaatgta
    40021 taagggaaaa attcaacaaa tgggaacacc acaagatata tacaatgaac ctaaaaattc
    40081 atttgtagct aagtttatag gtgaaagtaa catatttgat ggaattatga tagaggatta
    40141 taaagttaat ttctgtaata gggattttga gtgtgttgat aaaggattcg aaaaaaacga
    40201 aaatatagag gtagtaataa gaccagaaga tataaaaatg gtaaagccag aagaaggaat
    40261 gttaaagggg aaagttacat ctacagtgtt taaaggagtg cattacgaga tagaattgaa
    40321 tgaaaatgga agattgtgga tacttcataa tactaaaaat gctgaggttg ggactgaact
    40381 aggcatggat atatatccag aagatatcca tataatgaga aaagagagta actaagatga
    40441 aaagaaaatc ttttttagca tatccatatg tagtttggag tgcgatattt gtaataattc
    40501 ctttaatact agtggtattt tttagtttta caaaagaatc aggtggaggt tatgctttta
    40561 cacttgagaa ctataaagaa gtaatcgacc ctatatatat aaaagttttt gggcgttcta
    40621 ttcttttagc aggaggagcg acattgatat gtcttgtagt tggttatcct gtggcatata
    40681 taatttcaaa ggctcgtgta agcagaagag gttcattaat attattgttt attcttccta
    40741 tgtggatgaa ctttctttta agaacatatg catgggttgc tatattagga aaaaatggac
    40801 ttttaaatac atttttaggt tggtttggaa tacaaccatt agcaattttg tatactaact
    40861 ttgctatact tttgggtatg gtgtataact ttttaccatt tatggttctt ccaatatata
    40921 cagcactgtc aaagatggat aatgatttga taaacgctgc tcatgacttg ggtgcaaata
    40981 atatgacagt gtttagaaaa attatatttc ctttgagttt gccaggtgta atgtctggaa
    41041 taactatggt atttatgccg gcagtcacta cttttgcaat atcaagactg ttaggtggag
    41101 gtaaaatcat gctggttgga gacttgattg agcaacagtt tacagtcgtt ggagattgga
    41161 actttggttc agctatatca atatttatga tgatagtaat attaatatct atgtctataa
    41221 tgtcaaaatt tggagatgaa tctgacaaag aaggcggtgg gttactattt taaaattaaa
    41281 gaaaataact tctaatatat atttagcatt agtattctta tttttgtatg cacccatatt
    41341 tgctttggta ctattttctt ttaatgattc aaaatcaatg gcaagatgga atggatttac
    41401 atggaaatgg tatggtcaat tacttcaaaa tgagagtata atgagtgctt tatattatac
    41461 tattgtaata gctatattgg cgtctgtaat atctacaata gtagggacta taagtgctat
    41521 aggaatacat aagatgagag gtaagagtaa gaaattaata ctaaatgtaa actatcttcc
    41581 tattttgaat acagagatag ttacagcagt agctcttatg agtctatttg tatttgtaaa
    41641 aatggaattt ggatttacaa caatgttatt agcacatata atgttttgtt tgccatacgt
    41701 tatactttca gttttgccaa aaatgaagca attacctgat aatatagagg atgcagctat
    41761 ggatttagga gcaacaccta tatacgctct tagaaaagta attttaccac aaataaaacc
    41821 aggtatagtt tctggatttt taattgcgtt tactatgtca atagatgact ttataataag
    41881 tttctttaat gctggaaatg gtgtaagcaa tctttctata gaaatctatg gaatggctag
    41941 aagaggtata aaacctgaaa taaatgcatt atcaacaata atgtttgcag ttgttctagg
    42001 gttactttta ctggctaata aaaaagaatc tatagtaagg gggactaaat aatgattaag
    42061 tttaaaaaag caatatccct tatagctgta ggtatgatga cagttacttt atttacagga
    42121 tgtaataaag caacagattc tacaaaagtt ttaaatgtat ataatgttgg agattatata
    42181 gatgagtctc ttatagataa gtttgaaaaa gaaacaggaa tagatgttca atattcaact
    42241 tatgatacta atgaaatgat gtatcaaaag gtaaaaagtg gtagtacaca ctatgattta
    42301 gtatttcctt cagactatat ggtagagaaa atgaaaaatg aaggtctttt ggaaaaatta
    42361 gattttaaga atatacctaa tatgaagtat ttagataaga gttttttaaa tcctgtatac
    42421 gacaaaacta atgaatatag tgttgcatat atgtggggaa ctcttggaat attgtacaat
    42481 aagaaagaag ttaaagaccc tattgatagc tggaatatac tttggaatcc aaagtataag
    42541 ggaaatataa tgatgtttga ctctgttaga gatactatag gaataactct taaaaaatta
    42601 ggatatagca tgaacagtgt aaatccaaag gaaataaatg aagctaaaaa tcttttaatg
    42661 aaacaaaagg atttagtatt ggcttatgta aatgatgaag gcaaggatag attgcttggt
    42721 ggagaagtgg caatgggtat gctgtattct ggggatgcag ttacactaat ggaacaaaat
    42781 cctgaccttg attatgctat acctaaagag ggaactaata aatgggtaga tgctatgtgt
    42841 gtacctacaa cagcacaaaa taagaaagaa gctgagttgt ttataaactt tttattggac
    42901 ccagagaatg caaaagtaaa tgctgagtac atagggtatt caacacctaa tacaggagct
    42961 ctaaaattat tagacccgga aataactgag aatcctgttg catatccatc taaagaagta
    43021 cttaataaat gtgaaacttt tgaagatatt ggtgaaaata taaaattata tgataaggct
    43081 tggatagagt taaaatcaaa ataataataa ctataaagag gttgtctcga aattgagata
    43141 agcctctttt ttattgttga aaacatattc gatttcgtac aaaaaagagt gatttatgag
    43201 ttaaaaaatt tactttgaga cagtattttt ttattaagtt atattcatac acaatttaaa
    43261 tactttgtta ataaatgaaa acttatttgt ataatgactt taataataat tagaaagaat
    43321 gggcaactta atagaataat tggaggtgta aatttataaa aaatgaatat tgtaaataaa
    43381 aaaatagatt tattaatatt ggctttgctc gtttttatat ttttaattgt tggaatagta
    43441 atactatcca ttaggacaga aaataaattg aatgtgttta taatgctagc aataattttt
    43501 tttataataa tgttaactta tttgtcaaac tcaattgtgg gattaataac aagttcaata
    43561 attatattta tgtatacatc ctatatttta tataacaata ttacttacaa tatggatgtt
    43621 gaatttatat catatatgtg gataatagca ataccaatat cttcaattat aatgggtaat
    43681 ctgaacaaaa gcataaatga attgcaaaac acaaataaaa aactatctga acagtataag
    43741 gaattagtga ctattgatag tgaaactgga cttagaaatt taaagatttt ttataatgat
    43801 gtaaatatgg agataagtaa atctattaga cataatactg atttttctct tatgatagta
    43861 aaattaccat actatggaaa cctacagact atatttggtg aaagcaaaac taataaaata
    43921 gtaaaatata ttggttcaaa tattatagaa tgtacaagga atgaggatat aatatatagt
    43981 ttacaaaaag atatgctagg gatactaatg ccaaatacat ctttggaagg ttcaaaagtt
    44041 gttaaagaca gaataaagaa aaggataaaa gaactaaatt tagatttaaa caatagggga
    44101 aaatatgtaa atatagatgt caaaattgca tttttacaat atagggatag ttttggagat
    44161 agtataaatt ttaagaatat agttgaagag gaacttcaat atgatgttta aaatattcaa
    44221 taaaagtctg ttaaagttag tagctatatt atcaatagta ctgataatat caaattttag
    44281 tctatcttca tatgcatcag aaattacttc tagaacagat aatgtattaa tcgtatatga
    44341 ttctaagaaa gaaacagatt ataatagaga tattttaaat attatgagga ctctattggg
    44401 aagatttagt tcggatataa agctattaaa attgagtaac tatgatggtg agataaataa
    44461 aaattattac agtcacatat ttattttagg aatcaatgaa aattcatatg ataatgataa
    44521 taaaactaaa aacctgatta gttctttaaa tttatataaa ggaactatat gttggctagg
    44581 atatggtata gagaatcttt tggaacataa aaaatacaat ttagactata taggaaaaac
    44641 aaataatata gttagtgtaa attatagggg taaatcatat aatttagaag aacattatat
    44701 ttttaacatt gtagaatcaa aagatacaag taataaagta ataggaagta ttaatgatac
    44761 cttaaataag tatccatata taataaatga taaaaacctt ttttatgtat cgaaattaga
    44821 tttagatggt gttttatttt atatattttg cgattcactt aacgatattt ttaatattaa
    44881 gagatttgat aaaggacgta tatttgtaag aatagaagat gtacatgctt tcagagaccc
    44941 aaaagacctt gtaaatatag ctgattattt aagtagtaag gatataccat ttacaattgc
    45001 attgatacca gcttatgtaa atccaaaaaa tcataaaata acaactttat cagaaagccc
    45061 tgaaattgtc aaagcaataa aatatatgca agataaaggt ggaactgtaa tattgcatgg
    45121 atatactcat caatataaga aagaagaagt ttctggagaa ggatatgaat tttgggatgg
    45181 taaaaaagat gagcctttga aagaaaatat gaagatattt gtcaaagata gagttttaag
    45241 tggtcttaga gtatgtatag agaatggaat ttatcctctt gcatttgaag cgccacatta
    45301 tgcaatggaa tcagatggat ataaagaact aaaaaaatat ttttctactt atatggggca
    45361 acatcaaaat aacaataaaa aatttagtac aaatacatat ccttatatta ttagggatac
    45421 agaagagttt aatatactta tacctgaaaa tttaggatat atagacccag aagataagtt
    45481 tacttttcaa catataaaag aaaatttaga taaattatct attgtaagag gttttagtgg
    45541 aggttttttc ttccattcat atttgaacat agagtatcta aaaaacacga tagaatattt
    45601 agaaaaacag aatatagaat ttatgaattt aagagatttt aataattggg taaaagttga
    45661 tgaaatacaa ataagaaata atggagatga gattatagtc aattatgata gggatttaga
    45721 agaaaatatt aaaagtgata ttagatttaa gtctatatct aatattagta aaattttaat
    45781 attcatagta tctataagtg ttttaatatt tatgattata tttatatatt ttaagagaat
    45841 agataaaaag aaatttttaa aataaatgat tttatattag aattaatatt ttaaaatatt
    45901 ttaggagaaa tttatgagag atttaaatgt atcagagtgt ctgtttgtat ttagtctgtg
    45961 tagtatatgg tctttattgc ttataaatat tattttagct atgggtggat atatatttta
    46021 ctttaaaaac tttgataaag aaataaaaga aattgatgaa tatcctatgg tatcaatact
    46081 tgttcctgct cataatgaag ctaaagtgat aggtagaact gtggaatctt tattattact
    46141 caattatcct aagagtaaaa tggaacttat tgttataaat gacaattctt ctgataatag
    46201 taaagaaatt ttagaagata taaagaataa gtacaataac tataatttca ccataataaa
    46261 tacagatagt ttaacaggtg gaaaaggaaa atctaatgca ttaaatattg gatatacgat
    46321 ttcaaaagga gattttatag ctgtttatga tgcagataac acaccagata gaaatgcact
    46381 tagatattta gtacaaacta tagtaatgaa tgatgaatta ggtgctgtta ttgggaaatt
    46441 taggactcga aataaaaata aaaacctatt aaccaaattt ataaacatag aaacattaag
    46501 ttttcaatgg atgtcacaag ctggtagatg gcaacttttt aatctatgta caataccagg
    46561 aactaacttt atattgagga gaagtatcat agaggaaatt ggaggatggg atagtaaagc
    46621 aattgcagaa gatacagaaa taagttttag gatatataaa ttgggataca agataaagct
    46681 tgtaccacaa tctataacat gggaacaaga gccagaaact gttaaggtat ggataaaaca
    46741 acgtactaga tgggcaaaag ggaatatata tgtattaatg aaatacataa aaaatatatt
    46801 taagcaagga agaaataaga ttgtatttga tatagcttac tttttttctg tatattttct
    46861 atttttaaca tctgtcatta tatccgatat tttatttgtt ttaagtatat ctaagctagt
    46921 agaaatttct attccaatta acttttttct aatatggata ctatcttatc ttttatttat
    46981 tatagaagtg agtataagcc ttactataga aaaaggtgaa gcaacaatta aaaatatatt
    47041 catagttgca ataatgtatt ttacatactc tcaactatgg ttgtttgtcg ctataaaagg
    47101 aatgatagag tatctaaaag atataatttt taaaagagaa gttaaatggt ataaaacaga
    47161 aagattttaa ttcatgtaca ggaggaatta acatgaaaaa atttattata tcaattatat
    47221 ctttagtatt gtttttttca aatatatcac ttatagacaa agtaaatgct gacgagacta
    47281 aagttaaaaa ttataagttt gaaagagata taactattga tggtgttata ggaagtaata
    47341 gtactttttt tgaagtaaat aaaaattggg atattgaaga cgttttatta catcttaatt
    47401 ttagtaagag ccaaatatta aatggagatg tttcaagttt aactgttttg ataaataatg
    47461 taccaataaa atctattaaa ttaaatgcta agacaaatta taaaaataca ctagaagtat
    47521 tagttccaaa agattatata attcaaggct ataacgaaat aaaggtaaaa acatataaaa
    47581 caatatctga taaaatttgc caagatgatt ccaatactgg gaactggatg gttattcaca
    47641 aagaatcata tatatcaatt agatataaac aaaaaaagat ggaaaattca ataaatgaat
    47701 atccgtatcc atatgcagaa attgaaaata atcttaaatt agatacaaca atagtagtac
    47761 cagataatat gactagagga gagtctacag ctgtatttaa tttggcatca gaatttggaa
    47821 aaataataaa aaatgatgat ttaaagttag atgttaaatt atattcagaa atgaaaaatt
    47881 ggtcagatga taatattata tatattggta aacctgaaaa tacagcagaa gaaatcttgg
    47941 acattttaag tacagaggaa caaacactat tatcttcgaa ctgtctaatc aagcaagtag
    48001 attcaccata caataagaat aagaaaatga tggttgtaat tggtagtaat gaagaaaatt
    48061 taataaaggc atcaaattta ttaatagaaa atagactttc taatcaagtt ttatcatcat
    48121 cagtacttgt aaacaaagag actaatataa aaatcaatag agaacaaaaa ctaaacttag
    48181 gtcatttaac tttaaaagac ttaggatatt ctgacttttt gttggaagga gcatttaatc
    48241 aacaagcttt gtttgatgtc aaaataccga caggtaaggt actagatgat ggttcaaaga
    48301 ttgtcttgaa tttaagatac tctgacaatt tacattttga aaaatcttta gttacagtgt
    48361 ctataaatga tgttcttgtg ggaagtaaaa aattggatag gcaacattct aataatgata
    48421 agttagaatt aaaaatacct aaagatatag ataataaaaa ttattatcaa gtcaaattgg
    48481 tatttaattt gaatataaaa aattcgaatt gtgttactag agagagtaat aatccttggg
    48541 catatgtatc aaatagttct tatttggcgt tatctacaaa agaaaatgaa gctttatctt
    48601 ttgaaagtta tccgtatcca tttgttagaa atgatgagtt taatgattta actgtgataa
    48661 tgccagatta ttcagattca caagccatga catggatgtc taaactaggt gttactttgg
    48721 gtgcaaatat aaattcacat aatggaaata tgaatgtaat tagaggaaaa gagtttagcg
    48781 acaagtataa ggacaccaat attatagttt ttggagtacc gcataataat tctgttataa
    48841 agatgttaaa taataattta aatataaaat tcgataaaaa ttactccaat tttttatcaa
    48901 atgataagtt aagctttatt gatgattatg ggaaaaatat ttctaccatt caattaataa
    48961 aatcaccata taataatcaa aaaaatatca tggtaattag ttcaatgaat gaaaaaaact
    49021 tatatttagg aatggattat ttgttgaata aaagtaaagt taatgattta aaaggagata
    49081 cattgataat tgatgaatat ggagaggtag aagatttagc ttataattta aaacctaaga
    49141 aagaagtaaa aaattcaagt tggaatatga gtataaataa gacaaccaaa gtatttttaa
    49201 tgatttcttt tattactata attgtagtca taatattatc aatgttatat ataaaaaaat
    49261 ataaaagaag gtaatattat aaatttatta ttttaaaaga ggtatataat ttgaagaaat
    49321 atatgaataa gtttaaatta aaaagaaata ttttaatctc agtaatagta ttaattttta
    49381 tatttataat ttactttgta agtattgagt taaaagatag gagtctagta aataatcaat
    49441 ataaaggtaa gattaaatca gccaatttat ctgtagatta tgaaataagt caagttatga
    49501 aggatataga taaattagga ttgaatacag taaatgtacc tataattata aatgtagagt
    49561 ccattaattc tgatattatg tcaatagata ataatagtaa agaaaaggca attaagctaa
    49621 taaaaaaatt aaataaaaaa ggtatttcaa caatattaga ggcatatcca tggattgaaa
    49681 atggaaaatt gtatgaaact gactggaacc ctataaataa aaaaagattt ttttatactt
    49741 ggcaaaatac tatattaaat gaaattataa ttgatgtagc aaatccactg gacgtaaatg
    49801 ttttaaatat tggttctaat tttgtacatt tggaagggta tcaacaaaat tggagcgaaa
    49861 taatagattt tgtacaatcc aaatttgatg gtcttgtaac gtacagaact aattggtggt
    49921 atacaaaaaa agatgattta aatagtaagc tgtcttatga gcaaaaactg aataataatt
    49981 tttttgataa gttagatttt atatctatag cagcatattt tgagttaagc aataaacgta
    50041 ttaatacagt ggatgaatta atttctgcct tgtactcatc tactgtaaac aatagaagac
    50101 aaaatataaa aaaagaaata tataaccttt ataaggctca tagaaaaccc atattttttg
    50161 gagaattagg tttttcaaat agagaatatg caagttctca accgtggaat catgctactt
    50221 caaaagttgt aaatggcgaa gaacaagcaa ggtgttttga ggcatataag aaagtttttg
    50281 aaaatgaaga atggataaat ggtttttctg tgttttgtat aggtaaaata gatgacgaaa
    50341 aaaattttta cccatcaaaa gagagtataa aagttattaa gtcttggtac taataatttt
    50401 gaaagtttag aatttataga tgttaaatag atgattagga gagatataaa tgaatgacat
    50461 caaggttatg actgtatttg gaactagacc tgaagctatc aaagtagcac ctttaataaa
    50521 ggaacttgaa aaaagagcaa atataaaaag tattgtgtgt gttacagctc aacatagaga
    50581 aatgcttgac caagttatag aaacctttaa tataaatata gattatgatt tggatataat
    50641 ggaaaaagga caaagtctga atgatataac atgtaagatt ttaaataaac ttcccttgat
    50701 tttaaacaaa gaaaatccaa atatagtatt agtgcatgga gacacaacca caactctggc
    50761 tacaagcttg actgcatttt ataataaaat tattgtcggt catatagaag ctggtcttag
    50821 aacatatgat aaatattctc catttccaga agagttaaat aggcaactta caggtgttat
    50881 tgctgatatg cactttgctc ctactaattt ggctaaaaaa aacttgcttt ctgaaggaaa
    50941 gccctataat aatatatttg taactggtaa tactgctatt gatgctttaa agatgacaat
    51001 aaaagaaaat tatagtcacc ctataattga tgatattggc aatgatagga tgattttgtt
    51061 aacctctcac agaagagaaa atttgggtaa gcctatgaaa aatatattca aagctataaa
    51121 gcgaatagta gatgattttg aagatgtaca ggtagtatat cccatccatt taaatcctaa
    51181 aatacgaact atagctgatg agatatttgg gaaatttcct aaaaaaattc atattattga
    51241 acctttagat gtagctgact ttcataactt tttaaataaa tcttatatga taatgactga
    51301 tagtggagga atacaagaag aagctccgtc attaggtaag ccagttcttg tgttgcgtga
    51361 aaaaacagaa agaacagaag gaattgaagc aaatacactt aaattagtag gtactaatga
    51421 agatagaata tataattcag tgagtaattt attaataaat aaagataact atgttcagat
    51481 gagtaaagca tccaatccat atggggatgg aaatgcaagc aaatatatag ttgacataat
    51541 aattaaaaaa tttaattgta agtatttaaa ttaggttttt atgctcaact tgaaatttat
    51601 attagataag aattaaaaca ttaacgaatt gatataagat ttattatact atgagggata
    51661 caatttttaa gggggaataa tatggctaga aaattaataa aaaatttagg taaaagtaaa
    51721 agtgcaaaga gagtgaagct tttatttaag aagattttta ttactgtatt catagtagca
    51781 agtatagttg ctatttttaa tataacgaaa tattttgagg aattatacaa agtaagagat
    51841 ttaaaaagta ctaaaattga atactatatg gatgtagctg atgaagcagg ggatggaaag
    51901 gttcagttaa gttggaaggc cttacttgct atagacatgg taatacatga tgaagattta
    51961 agtaatataa aaaagaaaga cacattggat ataggagaaa aatttatagt agaagataaa
    52021 aatgataaag gcgaaaaggt gtataaggta aaaaagttta ataaggtatt aagcgaattg
    52081 aaatttgact cttctcaaaa aagtagagca agaaaataca tgaaggattt ggaatacaca
    52141 taccttggaa ataaacaatt agatagtagt gatgaaaaaa ttaaatttat aaagaaatta
    52201 gaagattcag ctataagaga atatattgat tatggaatat tgccttctat aacaattgga
    52261 caagctatat tagaatctgg ctggggaaat tctaaactta caaaacagag taataattta
    52321 tttggtataa aagcagataa agcatggaaa ggaaaaagtg tagaaatttc aacttcagag
    52381 cattataatg aaaaaattgt agctagtttt aggtcttata attcattaca agattctgtc
    52441 aaagaccaca gtttattttt aattaataat aaaagatata gaaaacatgg attgtttgag
    52501 gcaaaagatt atattagtca agctcaagca ttagaaaatg cagggtatag tacagcagaa
    52561 gataaaaaag gaaatcgtat atatgcagag ctattagtag atgttattag gagttataat
    52621 ttgcaactga tagacaacaa agttgagaca aaataattgt taactctata tgaagagatg
    52681 gcaagatgag attattttct acaaaagaat agaaaaattg taaaaaaaac taaaaaaatg
    52741 tattgacttg ttatttaaaa ggtgatatta ttattactgt actcgaaaga gaac
//
LOCUS       DBGJFK010000024        51753 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.024, whole genome shotgun sequence.
ACCESSION   DBGJFK010000024 DBGJFK010000000
VERSION     DBGJFK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.024"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            136..945
                     /locus_tag="ACOIAP_001616"
     CDS             136..945
                     /locus_tag="ACOIAP_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2638504.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELNLIDKKVAELISHKEN
                     IIKRLSSIESAVKNTKIDEIEVIYIKKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKVYMEKVFEFIEENNYKVIADPIEIYKIDIHETGIVEEFITEIQVPIIK"
     gene            complement(1054..1263)
                     /locus_tag="ACOIAP_001617"
     CDS             complement(1054..1263)
                     /locus_tag="ACOIAP_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638505.1"
                     /translation="MGNNDKEKSKNSKNIFHDIPVLVNNFFWSMIGFIVIKNFGNGNF
                     FTYLLGIGAGLLWGIFIQKFFTNNK"
     gene            complement(1749..2423)
                     /locus_tag="ACOIAP_001618"
     CDS             complement(1749..2423)
                     /locus_tag="ACOIAP_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGZ2638506.1"
                     /translation="MNHYILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     KADSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            2826..2960
                     /locus_tag="ACOIAP_001619"
     CDS             2826..2960
                     /locus_tag="ACOIAP_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638507.1"
                     /translation="MNISRKAMKIIELAQKIANKRGISVEEAWNEAVTEYKNKYEHIA
                     "
     gene            3060..3845
                     /locus_tag="ACOIAP_001620"
     CDS             3060..3845
                     /locus_tag="ACOIAP_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2638508.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVKDGNITSIILKNKSTLIIYSFKNNFDIEEMKNHIKNLDVESISGKKCVIDRLISE
                     YKNFYEKLDNKFCVLKEMKEIDFSNMKGYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRKNDTMISTVSTGMETSFLAMVVSISTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDIAGKIYHNIGYKEVNEWTILFK"
     gene            complement(3941..4765)
                     /gene="pdaA"
                     /locus_tag="ACOIAP_001621"
     CDS             complement(3941..4765)
                     /gene="pdaA"
                     /locus_tag="ACOIAP_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HGZ2638509.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYDAYYVGNPKEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPDLIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEREGYKLKTLDYLSNKK"
     gene            4988..8107
                     /locus_tag="ACOIAP_001622"
     CDS             4988..8107
                     /locus_tag="ACOIAP_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HGZ2638510.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYYMPKLKNKFIDLIELAVILEPYYKDYSLEYLKNTLTNFNSKVENRALSDAIDII
                     NIVNCLLVRFNSYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINLKK
                     EYNIFDSKEEKKKERETLKILNEEENHYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLE
                     RLVEGGKYGDIEEINYSVFDNFKEISIHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIEREDKQKIARSINLIIEEIDSIL
                     NFGSCNEYDSVSNYNLRWELNLQIDEILGKLKKDGVDTEISYRAYSEKIKLGCEKIIK
                     NLVLIIITIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISQITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYNIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRQHLNKSRSLILKSVIFDTIKA
                     LNVDSKMNNNDVDKDIIKKDINENIRQRAVKGEVYHIDILKKDIKVKYFNKNYLINLD
                     IFMREENKN"
     gene            8124..8723
                     /locus_tag="ACOIAP_001623"
     CDS             8124..8723
                     /locus_tag="ACOIAP_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viroplasmin family protein"
                     /protein_id="HGZ2638511.1"
                     /translation="MAKQKFYAVKKGKNIGIYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIYGAEKFSFKEDKEFIEAYVDGSYEHSIKMYGSGVVILKNNEVIKTYSEKGKEE
                     TLVGMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(8936..11065)
                     /locus_tag="ACOIAP_001624"
     CDS             complement(8936..11065)
                     /locus_tag="ACOIAP_001624"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0098869 - cellular oxidant detoxification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HGZ2638512.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGSIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNAEE
                     VNKKIDNTCSWKKEHTKNIENECNCEHEHHDYMNKALDCKQEHMTDIKDDCNQEKKHT
                     KNTNKTHSSKQNKFKDKSCDEMKFNYDKDESCDKINSSYDKDDSSYEYFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKAEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGIVSRPQDRENFTLLLTAIR
                     DVIGDEKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNARKHQSN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPFLVKDGEFAMAYDDSLSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            11331..11579
                     /locus_tag="ACOIAP_001625"
     CDS             11331..11579
                     /locus_tag="ACOIAP_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638513.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTFGIVL
                     CNARKIFDSKTIHKTRMKNVSTNKKQKSHSRDIKRKIS"
     gene            11745..13136
                     /locus_tag="ACOIAP_001626"
     CDS             11745..13136
                     /locus_tag="ACOIAP_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HGZ2638514.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIVLMIVFFLSSNE
                     FSVGKEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELKKISIDVDDLLAQADRVREMYKEENTTYDIAINYIN
                     TVSLLNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKVYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKEDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNALDEKE
                     NKYKKIEILDIEKADRYSKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAVSENGLNEY"
     gene            13251..14705
                     /locus_tag="ACOIAP_001627"
     CDS             13251..14705
                     /locus_tag="ACOIAP_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HGZ2638515.1"
                     /translation="MSNMNKKLVIAIGAVALVAIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVEFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SGFFGNLSKTISANFGKKSNLVVVVNYDKNKLKAEMGKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDVSKSMETFDNQTKKGNYKNKLAVKATPAKVKKEQLANIDTNLGKY
                     STTFKTSQINRSINIKLATDSISNILLMPGETFSFNEHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIANVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPS
                     TDENKNNQNTNNQQKPETPPTDNKPNETPPQPQD"
     gene            14770..15363
                     /locus_tag="ACOIAP_001628"
     CDS             14770..15363
                     /locus_tag="ACOIAP_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2638516.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            15494..16891
                     /locus_tag="ACOIAP_001629"
     CDS             15494..16891
                     /locus_tag="ACOIAP_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGZ2638517.1"
                     /translation="MEVSIILVKDIKQDIESMPRKILDISLIEDNKSDLTFFNIEEED
                     GDETLKALKQSYVTTNYKEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKN
                     YITSAINMVNKALEINPKDIDILNLRGLLKLLKCDFAKAFESFYTALCYENNHISRKY
                     VNLISSEDFKTFLGRYNHSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDK
                     LGNVKKREGYLDKLKELDKDNPVFEKNEEEKEDISKNEETKKVKRKKNILPYIIVGCV
                     LIGMGLYLIQSKKRIENLNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEP
                     ERKITVADEEDLYYQALDLKKKKEYEKAIENFKSIVSSGKTKKYISESIYQLAITNKL
                     LGNKDEAIKYYKKYINTYTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPD
                     SMYNNSKIKEILSEK"
     gene            17073..17444
                     /locus_tag="ACOIAP_001630"
     CDS             17073..17444
                     /locus_tag="ACOIAP_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HGZ2638518.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            17437..18126
                     /locus_tag="ACOIAP_001631"
     CDS             17437..18126
                     /locus_tag="ACOIAP_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HGZ2638519.1"
                     /translation="MYNVLHTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIIGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIAGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMIASTVFKLGNINHPVAKGIALGTSAHALGTTKAFEFGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            18646..19512
                     /locus_tag="ACOIAP_001632"
     CDS             18646..19512
                     /locus_tag="ACOIAP_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2638520.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISKIIPIHDILLQSVYGGILSGLGVGIVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSDEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            19754..20563
                     /locus_tag="ACOIAP_001633"
     CDS             19754..20563
                     /locus_tag="ACOIAP_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGZ2638521.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVSKEIRSIKSMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYIGKFLEGKMEGKGSYTFFVDEGT
                     AMEYIGEFKEDKKNGKGNFVFSNGNEYIGYFEEDMMNGIGNMLYNSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEILYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            20704..21768
                     /locus_tag="ACOIAP_001634"
     CDS             20704..21768
                     /locus_tag="ACOIAP_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HGZ2638522.1"
                     /translation="MKKLIALVLVILIVLFYSPELLKEGNDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKNQNVQSNNTEGDNLGESDIKNFEKISLEDNLSYVLSSIGKPGRI
                     DTSEYGFDWYVYNQYGKEFAMVGVENDEVVALYSNSINSSENQGIKINQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEKNRVCSYLIIDKSTEDEFK
                     KLYPDDREELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            21796..22515
                     /locus_tag="ACOIAP_001635"
     CDS             21796..22515
                     /locus_tag="ACOIAP_001635"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2638523.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIILISNFSKVSALMTDTSGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            22538..23122
                     /locus_tag="ACOIAP_001636"
     CDS             22538..23122
                     /locus_tag="ACOIAP_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGZ2638524.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKIRDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEYFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSISHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEVTATTDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFIIEARERVHM"
     gene            23124..24473
                     /gene="pabB"
                     /locus_tag="ACOIAP_001637"
     CDS             23124..24473
                     /gene="pabB"
                     /locus_tag="ACOIAP_001637"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGZ2638525.1"
                     /translation="MIREINTTLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVINDTNLPFVGGAVGYLSYDLGNYIETLPRT
                     AIDDIKMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIKLEEKIMDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDTHILSNSPERFIRCVNNRIETRPIKGTRPRGKNKE
                     EDLKLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDGKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            24463..25206
                     /locus_tag="ACOIAP_001638"
     CDS             24463..25206
                     /locus_tag="ACOIAP_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HGZ2638526.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIKVKNGLPIDLNIHVERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVIDKALRITVFDEGYNISIRDIPYNQEMYEKGF
                     RLTISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIEELLE"
     gene            25240..25941
                     /locus_tag="ACOIAP_001639"
     CDS             25240..25941
                     /locus_tag="ACOIAP_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638527.1"
                     /translation="MIGCIYEVYNEEISKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDINYFSKDGIKKLLSNREYFFVKEMKDAKVLF
                     DRENISHTIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            25967..26539
                     /gene="folE"
                     /locus_tag="ACOIAP_001640"
     CDS             25967..26539
                     /gene="folE"
                     /locus_tag="ACOIAP_001640"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGZ2638528.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLNEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            26605..27396
                     /gene="folP"
                     /locus_tag="ACOIAP_001641"
     CDS             26605..27396
                     /gene="folP"
                     /locus_tag="ACOIAP_001641"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGZ2638529.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKISIEMA
                     ISCGVKKEKIVLDPGIGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            27407..27772
                     /gene="folB"
                     /locus_tag="ACOIAP_001642"
     CDS             27407..27772
                     /gene="folB"
                     /locus_tag="ACOIAP_001642"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HGZ2638530.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYDVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            27765..28271
                     /gene="folK"
                     /locus_tag="ACOIAP_001643"
     CDS             27765..28271
                     /gene="folK"
                     /locus_tag="ACOIAP_001643"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGZ2638531.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERKLHRERIVHWGPRTIDVDILFFN
                     DVVSTDERLIIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEERDEVKEL
                     VGYERKPI"
     gene            28252..29037
                     /gene="aroF"
                     /locus_tag="ACOIAP_001644"
     CDS             28252..29037
                     /gene="aroF"
                     /locus_tag="ACOIAP_001644"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGZ2638532.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            29292..31082
                     /gene="dnaG"
                     /locus_tag="ACOIAP_001645"
     CDS             29292..31082
                     /gene="dnaG"
                     /locus_tag="ACOIAP_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGZ2638533.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMSIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDIINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGLLIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            31100..32266
                     /gene="rpoD"
                     /locus_tag="ACOIAP_001646"
     CDS             31100..32266
                     /gene="rpoD"
                     /locus_tag="ACOIAP_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGZ2638534.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHEDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            32428..33117
                     /locus_tag="ACOIAP_001647"
     CDS             32428..33117
                     /locus_tag="ACOIAP_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGZ2638535.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGRVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFKDFIEKKIKTYSSIVSKLEGKNGEAIDKKRNESE
                     VTIKKLENLIK"
     gene            33131..34228
                     /locus_tag="ACOIAP_001648"
     CDS             33131..34228
                     /locus_tag="ACOIAP_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGZ2638536.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSADLKGRLIQKLIKNNVSLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDVTKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSKKIKEKLNMKHIRVVGNLS
                     TNITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEISEIEVIKSSVYLNPFSTI"
     gene            34290..34862
                     /locus_tag="ACOIAP_001649"
     CDS             34290..34862
                     /locus_tag="ACOIAP_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2638537.1"
                     /translation="MKAAVIFHSVCGSTYLLAREYKEALKEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGRELLDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSIRGGHPAYG
                     ILHIAGDNSNIRPSDDVKIGIRDYLERLSI"
     gene            complement(34922..35389)
                     /locus_tag="ACOIAP_001650"
     CDS             complement(34922..35389)
                     /locus_tag="ACOIAP_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HGZ2638538.1"
                     /translation="MFKEMRLKKREMTKEDTIEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFDDSIYFHSARNGHKLDNILKNNKVSFLVVANENVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDVNLTTVVKIEIDHISGKASRL"
     gene            complement(35775..36251)
                     /locus_tag="ACOIAP_001651"
     CDS             complement(35775..36251)
                     /locus_tag="ACOIAP_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGZ2638539.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLNVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(36368..37459)
                     /locus_tag="ACOIAP_001652"
     CDS             complement(36368..37459)
                     /locus_tag="ACOIAP_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5808 domain-containing protein"
                     /protein_id="HGZ2638540.1"
                     /translation="MSKIECLFTIFPILILMYATFYFMPYFVGKKHIYGVSIDQEYKN
                     YNHFIKLDKKFKNLLSLGFIIDLILVFILVFTFNKLELSYFISIIVFLLYESILYIHT
                     HKKAKNLKSELYSKLGHIDVDSKLIIDMDFINKKNKIIKKFKIIYLIPILFTFGMSIF
                     IVFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTNFCLMVLLYITSIGSIKSR
                     IKIDTNRIKESRIENIEYLNKIGYLFLILMTIMTIQFFTTILSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKSNSSYSPEENEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFLLFSLIKSLLL"
     gene            complement(37452..37841)
                     /locus_tag="ACOIAP_001653"
     CDS             complement(37452..37841)
                     /locus_tag="ACOIAP_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2638541.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDNYEVKYYE"
     gene            38033..38479
                     /locus_tag="ACOIAP_001654"
     CDS             38033..38479
                     /locus_tag="ACOIAP_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638542.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMLTGAVLTGVGAYAVYKMIKNRK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKDDVDLHEDAKKDNIYKEDEYKKYEEE"
     gene            38746..39450
                     /locus_tag="ACOIAP_001655"
     CDS             38746..39450
                     /locus_tag="ACOIAP_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2638543.1"
                     /translation="MVKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSGKEMISSN
                     EYSLILLDVTLPDGTGYELCQYIRGFSQIPIIFLTACDEEVNIVMGLDIGGDDYITKP
                     FRIRELISRIKAVLRRKANTVEESKKILKFGDLSIYTLEARVYKNDKEVFLTSVEYKL
                     LLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCEPIYIETV
                     RGLGYKWIGSENSVSI"
     gene            39428..40681
                     /locus_tag="ACOIAP_001656"
     CDS             39428..40681
                     /locus_tag="ACOIAP_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2638544.1"
                     /translation="MKIVFLYNPEVKKFLSKYVTLIFVIIIISIGFSVINVSLTKDMI
                     VRNNQAIIGTLSSKYPNLESEIVDIITQGKSMENTDYGKKILSKYNYDKSIRINSEPI
                     ISKLVLDTIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKSFDMKN
                     KNQEGQIGLLKTELLKMTTILNEKVELLKTEKIFLNNTISDISHQLKTPMTSLIMLND
                     LLYNDIPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHR
                     AMQSMKIPMEIKNQKLTIEGSDNISYIGDIDWSVEALVNIIKNCVEHTPEFGNITITY
                     KENPLFSELIIKDDGEGIHKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNG
                     DIYVNSEKGKGTEFHIIFHKMYDSD"
     gene            40761..41438
                     /locus_tag="ACOIAP_001657"
     CDS             40761..41438
                     /locus_tag="ACOIAP_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638545.1"
                     /translation="MEVLRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLNDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            41439..44000
                     /locus_tag="ACOIAP_001658"
     CDS             41439..44000
                     /locus_tag="ACOIAP_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638546.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQVRETIKNDGSFHVTFYDVNRKNVEYVTKSAEVEKYAFTKQLGYSKLENSENGIVS
                     IKQYDKNAINGYKISIKEGRFPAKEGEIVLSENIINLIDDNLKIGDKITLKVGDMFDS
                     SKKKIDSMVFHEGDYIASEKDRTFEVVGIIKKPGFERYNGIATAITYFNPMDNYNDTI
                     NVSVEVRNPKEVYEVSNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYADINSSI
                     KSIIIAVTILVIICTIATVYNSFSISITERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTQMSLRIVYNPIIIIVSIIIVLFTIF
                     ISILLPAISASNISPLNVIKNTGEYKVRKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IVTLFSLMISVIIFISFSGFTLLLLRSEEIRNSQRKYDLYLTAKGTARSIDDTVSELE
                     GIDGIKNFELATGQYVSIRVSENKINKSKEDLIGKYYQKYKVGDSYEYDFSNNDLIFP
                     GDFAIRNKINNLIQGSFNKERAIQENGVILVRKSSFESKGKKGVVELTNYKVGDTVTC
                     EYLDENASSKKIKVKILAITDEERLGMGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESAITESEKQNLKVIKIFVYGFIAVISLVSVTNI
                     LNTVSTSINLRKGELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGMTLIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPISKLNKENIIDNIRRESI"
     gene            44220..45494
                     /locus_tag="ACOIAP_001659"
     CDS             44220..45494
                     /locus_tag="ACOIAP_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2638547.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKVECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHESCVKCGKCIAACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(45656..48697)
                     /locus_tag="ACOIAP_001660"
     CDS             complement(45656..48697)
                     /locus_tag="ACOIAP_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HGZ2638548.1"
                     /translation="MFKRKLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNSESYTKTKALAKEKIQTLLSKYGVVNAQYALIDNGKIEISGNGGVYSKQD
                     NKNLTKDNMYSIASISKMFTTTAVMKLVDDGKVNLDTPVVNYIPEFKMADNRYKEITP
                     RMLLNHSSGLMGSSFKNTLLLGDNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGNSQFDEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSHLKENSGLYASSNMVKVDVNDNG
                     TLTVSSPYIENGPEDKYIYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRNGKGYYLVDEKYTSQSYMFGSVKATPGLSD
                     ETPGYIVNTKIIDENNSNAFIEIPGVIGRDLSDIKLYKENGTEYLSFATQTYVSEDSI
                     TNLPAEKSFTCELASNGYAKWYKIGDDIANKKIEVNLPQNSSFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINENSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVI
                     LVGNSLDYNQKELFKTMRFKSITQIGGNGNENSFKQIKEIA"
     gene            48905..49204
                     /locus_tag="ACOIAP_001661"
     CDS             48905..49204
                     /locus_tag="ACOIAP_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGZ2638549.1"
                     /translation="MYKNINKNQLKEMMKNEKDILLLDVRTKDEFREHKIENAINISL
                     QELINNIDEIYEYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMN"
     gene            complement(49440..51668)
                     /locus_tag="ACOIAP_001662"
     CDS             complement(49440..51668)
                     /locus_tag="ACOIAP_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HGZ2638550.1"
                     /translation="MIHLKKTNSLKEILNWNNIKNLKPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITNDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVINNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSVSALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAESKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIETLNKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIILLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRIIKPFNDKFGDSNLT
                     GH"
BASE COUNT        20638 a         5523 c         8516 g        17076 t
ORIGIN      
        1 ataattaatt gtaggatgtt tattttccta tccttgtttt agagattttt ttagtatatt
       61 ctaatactat agtattatag agtaataatg ttaatttaaa ataaaaatag ggttatggag
      121 gagtttatta tataaatgaa agattactat aaaataggag agatatctaa aatatatgga
      181 ataggcagag attcattaat gtattatgag gaaataggga ttctaagacc agttagagat
      241 ataaatgggt atagaatgta taatatatca gacatatgga aactaaattt aataaaagaa
      301 tttagaagtt tgaactttcc aatgaaaaaa ataaaagaat atttagatga tagaagtata
      361 gagtctacga aaaacatctt aaatgaggag cttaatttaa ttgataaaaa agtagctgaa
      421 cttataagtc ataaggaaaa tattataaaa agattaagtt cgattgaaag tgcagttaaa
      481 aatacaaaaa tagatgagat agaggtcata tatataaaaa aaagaaaagc tttagaatta
      541 aatgctgata taaagagaga tgaagatttt gactttttaa ttcaaaagct tcagaaagaa
      601 tatgaagata gatttaatat acttggaaac aacaatattg gttctgcttt ttctactgaa
      661 gcaattaata aaggtatatt taatgaattt aaatctgtgt tttgttttct ggaaagtaat
      721 gagaaagtat acaatatagt ttttgatgaa gggtattatg tgactttaaa ttatactgga
      781 agtaattcta acaataaggt atatatggag aaggtatttg aatttataga agaaaataat
      841 tataaagtaa ttgctgaccc tatagaaata tacaagatag atatacatga aactggaatt
      901 gtagaggagt ttataactga aattcaagtt cctataatta aatagctaga tttcaacaaa
      961 ttagatgata aatagtataa aaaaatgagt ttaccactat attataaaag tagtggtaca
     1021 ttttttattt gggatttttt gtttaagatg tgtttactta ttattagtaa aaaatttttg
     1081 tataaatatt ccccacaata aacctgctcc aatacctaat aaataagtaa agaagtttcc
     1141 attcccaaaa ttttttataa caataaatcc tatcattgac caaaaaaaat tgtttaccaa
     1201 tactgggatg tcatgaaata tgtttttact attttttgat ttttctttgt cattattacc
     1261 cataatgtca tctccttacc ataagcattg aacactgtgc attacctaga aatcattgaa
     1321 atatttaaac taatttttta gcataagatt atttataaat tagattaaaa taaaaaggat
     1381 atacgttttt acaactagat aaaataactc ataatatatt ttataaatat cagtacatat
     1441 agctttatat cattaaagtt ctctagtttt gatgatttag tttaatttta tagtttaata
     1501 gtacaataga attatttatt gttcaacata tgtattttaa agttgaaaaa atttatagat
     1561 atgaagacta ttgtacaact aaaaatgcac tagatgtcta gaactatggc aactatactg
     1621 tagtttttta ataaaatata tatgtgaatt gataaaaata agggacgaac tttatataga
     1681 atcatccctt gatatctgca tttttatttt aattaaatat attattatct ttaaagttct
     1741 attttacatt atatttctaa tgtttctata agaggattat cgctaaataa ttttaataaa
     1801 tttgtttttt tgtatccttt aggtaactta gtatatataa ctacctctaa ccaatctcca
     1861 tcaagacgtt taatattcat gtttataatt tcaatattag attttttaaa tttaccttca
     1921 atatattcta tagaatcagc tttattagaa atcttaagag aaacttgttc tgctgtaggg
     1981 agtttcatcc atttcctatc tctatgaagt gttatctgta caataacaat aatgatactt
     2041 gaaacaatac caactaagta taatccagag ccaatggcaa gacctgtacc ggctgttgcc
     2101 catataccag cagctgtagt aagaccactt actgattgat ttctaataaa tattaatcca
     2161 gcacctaaaa aacctatccc actgacaact tgtgctgcaa cgcgggctgg gtctagacca
     2221 atacctggag tacccactat atcattaaat ccatacttgg aaacaatgat tataagtgct
     2281 gaagctaatg ccactataaa atgagtgcgt attccagctt cttttagtct attctttctc
     2341 tcatatccaa ttaaagctcc acagaaacca gcagtaatga ttcttgctat gtattcaaat
     2401 tgaatcaata tataatggtt catttgtcta gcaccccttt ctatataata ttatatatac
     2461 tataatacta cattttttat gtgaatatag taaagtttaa aatttatata atagttatat
     2521 atgaatataa aataaataaa agtacattat gtatataaaa agtatctaat tttaaattat
     2581 taaagagtaa actaaactta cttttttaac atattgaatg ttttttattt gtaatagcta
     2641 gataaatacg acaaatatat atgaattgta tataaatttt atgttttatt aagttctaaa
     2701 tttcttctat tgtagttcat atttagtaca taaataatta gtaagatata agtaaataaa
     2761 tatataacat gactatagaa atttaacttt aaaataactt atgataattt agaggaggaa
     2821 tatatatgaa tatatcaaga aaagctatga aaataataga attagcacaa aaaattgcaa
     2881 ataagagagg tatatcagta gaagaagctt ggaatgaagc agtaacagag tataaaaata
     2941 aatacgaaca tattgcataa atatttaaaa atttagaata tttggtagaa tataatgatt
     3001 ttaaatgata ctataaatta taaggtatat cattattaac atagaaggag gatatctgct
     3061 tgattgtaaa aatagataat actttagaaa aagaattttg gcaatatgta tcacatgaag
     3121 aaagtttaaa tttattcata attggatacg ttgagaatta cggatttagc tctcaatatc
     3181 aagatatatg gtctcaggta aaagatggaa atataacttc tataatatta aaaaataagt
     3241 cgacacttat aatttatagt tttaaaaata attttgatat agaagaaatg aagaatcata
     3301 taaaaaattt agatgtagaa agtataagtg gaaaaaagtg tgtaatagat agactaataa
     3361 gtgaatacaa aaatttttat gaaaaactag ataataaatt ttgtgtatta aaagaaatga
     3421 aagaaataga tttttccaat atgaaggggt ataaaataga aaatgctcag gaaaaagata
     3481 ttgatgaaat aggaaaactt ttaaataggt cagattataa agtaagtaaa aattatatag
     3541 aagaaagaaa agagcattta aaagagggga atgtaagagc atattttatt agaaagaatg
     3601 atactatgat tagtactgtg tcaactggta tggaaactag ttttttggca atggtggtct
     3661 ctataagtac agataaaaga tataggggaa aaggacttgc aagttacatg gtttacaatt
     3721 tgagtaaaga attattgctg gaaggaaaag ttccatgtct tttttataac aatgatatag
     3781 caggtaaaat atatcataat ataggatata aagaggtaaa tgaatggaca attcttttta
     3841 aataactata aaaaataaaa aactctatcg agaattaaag tatttataaa tagctatatt
     3901 ttactataat tcatgatgga gtttttttta atttatgata ttatttttta ttacttaaat
     3961 aatcaagtgt tttaagttta taaccttctc tttcccaatg tgtaagaacc tcatctaata
     4021 tctcagtatt tgttgatgaa tttggatgca gtaaaactat tgcaccagga tgagttcttg
     4081 aataaatttt gtttttggca aattcatgag taggttgttt cttttcatac caatctacat
     4141 aagcaaaact ccaaaatatt gatttatatc ctaaatcttg tgtatatttt aaagattgtt
     4201 cgctaaattt acccattgga ggtctaaaat acttaggcat ttcttttcca gtaacatctt
     4261 tgtatgcttt ttctacgctt gtaatttctt ctttaaattt ttcaaaatct gtaatacctg
     4321 ccattgatgg atggcttttt gaatgattac aaactaaatg tccttctttt tccatacgct
     4381 ttattaaatc tggattgctt tttatataac tttcaactac gaaaaattgt gctttagcat
     4441 tgtgtttttt tagtgtatct aataattttg gagtgtttcc actttcatat ccagcatcaa
     4501 atgatagata tataactttt tctttgggat ttcctacata ataagcatca tattttttaa
     4561 aaaaatcagc ttcttttata ggtgatggct gtttaccatc ctctctaggg ttaaaatacc
     4621 aatcatattc atgtgtgtcg agtgttggac tagaaatttg agtttttgtt ttatctaatg
     4681 atttaaaatt tatactagca attccaaaaa gtattagggc aaatgctcct atcataatgt
     4741 atttttttag gctatctttt ttcacaattt cacctcttat ttaaaattta aagtatattt
     4801 cttataatat agtttgaata tttatagtta aaaatattca tatatacaaa taataaatga
     4861 aagaagttta ctgtaagata tataaagtta ctattaatta tcttaaataa agtgtatata
     4921 aatgataaaa tataaagaga aatgattgta aataagttag gcgggtttaa cttgaaggga
     4981 tataaaaatg gataatataa taagtgtatt gaatgatgtt gtttttttag atatagaagt
     5041 tagtggatta gattgtttaa attcagaaat tttagaagtt ggagctgtca aggttaaaga
     5101 ctggaaaata tatacctatg aatcattaat aaaaaacaaa tttgaggtac ctatagaagt
     5161 attctcagta tgtaaaaatt tagataaaaa tgatttagaa atagctaatg aaatagaact
     5221 ggtggaagat agacttgtaa attttgtaga agatagtttc attatatgtc atgatttaag
     5281 tctgaaaaaa aagttttttg agtattatat gccaaagtta aaaaataagt ttattgattt
     5341 aattgaatta gcagttattt tagaaccata ttataaagat tatagtttag aatacttaaa
     5401 aaatacttta acaaatttta attctaaggt ggaaaataga gctttgtcag atgctattga
     5461 tataataaat attgtaaatt gccttctagt aagatttaat agctatgaaa aaactacttt
     5521 ggaaccattg agttttaaaa taaactcata tcttaaaaaa tttaatctcc caacatggga
     5581 atggagcaaa tttttagaag aggcaaatta tgatttatca aataatataa acctcaaaaa
     5641 agaatataat atatttgact cgaaagaaga aaaaaagaag gaaagagaaa ccttaaaaat
     5701 tttaaatgaa gaagaaaatc attatgaaga attattaaaa tacaaaacta tatgggagaa
     5761 taaagaagga tttacatatg aatataggcc tggtcaatat gagcttacta aaacaataag
     5821 agagttgttt agaaatagcg aagatgaaga aaaaattgca tgtatagaag cgccaactgg
     5881 tataggtaaa agtgtaggat atttactgcc tgcaatatta gaagctagaa ttaataaaaa
     5941 aagattatta atttctactg atacaaagga attgcagata caattaataa ataaagatat
     6001 tccaaacgtg ttagattctt tagggctaaa tggaaaagta agttatggat atataaaggg
     6061 aaaaaataac tatatttgta tagatagact ggaagcatat atagatgatt atgagtctca
     6121 aaatcctact aaaggagaaa ttttatcttt aatatttttg gagagattag ttgaaggtgg
     6181 taagtatgga gatatagaag aaataaatta ttcggtgttt gacaacttca aggaaataag
     6241 tattcactta agaaatgtaa gttgtgaccc aaatatgtgt agacctaaaa aatgcaaaaa
     6301 agattgtcta tataaaaaca gaatagaaga attgaaagaa gaacatataa cagtagtaaa
     6361 tcattcacta ttagctaaat ggccgtataa ggatgaaaaa cctttagaaa atataatagt
     6421 agacgaagca cataatttga ctgaaaaagg atatgatttc ttttcaagca ttataaactc
     6481 aaagtcctta aggtatttat tacaagaaat ttatccttac gagtttattc aaaatagtag
     6541 ctttatatat aaaaaatata gcagaaatat gaggaaaata aaggcttttg ataaatttta
     6601 taatgtatta aaaattgaaa gggaagataa acaaaaaatt gctagaagta taaatcttat
     6661 tattgaagag atagattcaa tattaaattt tggtagttgt aatgaatatg atagtgtaag
     6721 caattataat ttaagatggg aactgaattt gcaaatagat gaaatattgg gaaaactaaa
     6781 aaaagatggt gtagatactg agataagtta tagagcttat agtgaaaaga taaaattggg
     6841 ttgcgaaaaa ataataaaaa atttagtttt aataataata acaatttata ggaatattga
     6901 tgatgatagt atagataaag aagcagatat atataaattt ggaaaggcaa aaacaagaga
     6961 tttagaggat ataaagatta tatttgaaat ctttttagag tatgatgaaa aagatgatta
     7021 tgcaaggata gttgaaattg ataagaatta taatgacttt gaatttcgag tagtgccatt
     7081 aaaaatagca gatttatttg aagaaaatat tttatctcaa ttagagaaag gaatattttt
     7141 atctgcaact ttgagtttat ctgaaagtat gtcttatttt aaaaatacat taggaataga
     7201 cagagttaag aatgtggaaa agattataga accaattttt gattataaaa atagagtctc
     7261 tgtagttggg ttttctgata tttgtgagta cagaaattct gaatttccaa atgaaatgag
     7321 taaaattata tctaatatat cacagattac agaaggtcat acattagctc tttttaatag
     7381 taaagataga caagaaaaga cttatgaaat attgaaaaaa tacttacata gttttaattt
     7441 agaaatttat gctgataaaa aaggaattag gcaccttaac gatttaaata gaaagtgtgt
     7501 agtacttggc tcaaaaggat gttttgaagg agtagatatt ccaggggatg gtttggtttg
     7561 tgtaacttta gacaagcttc cgaatctaaa tccaaaagac cctttgtatt ttactataat
     7621 gaagaagtat aatatagact actatactat aaattatcct caaatgacca taaaggtaaa
     7681 gcaagctatg gggagaattt taagaagtaa atacgactat ggatgttttg tcatttttga
     7741 tgtaggaact aatataagtg tgttaaagag attagagaaa gatttacacg attgtaaaat
     7801 ttcaaaggtt aatagcaatg agttttatac ttatataaga caacatttaa ataaatctag
     7861 aagcttaata ctaaaatctg ttatatttga tactataaaa gcgttgaatg ttgattctaa
     7921 aatgaataac aatgatgttg ataaagatat tataaaaaaa gatattaatg aaaatataag
     7981 acaaagagct gtaaaaggag aagtatatca tattgatatt ttgaaaaaag atattaaagt
     8041 aaaatatttt aataaaaatt atcttataaa tttagatata tttatgagag aagaaaataa
     8101 aaattaagag tggagtgata tatttggcaa aacaaaagtt ttatgctgtg aaaaaaggta
     8161 aaaatatagg tatatataat acatgggatg agtgcaaaaa gcaagtaaat ggattctcag
     8221 gagctgaata taagagtttt tctacttttc aagaagctaa agaatatatt tatggggcag
     8281 aaaaatttag ttttaaagaa gataaggaat ttatagaagc atatgtagat ggaagttatg
     8341 aacattcaat aaagatgtat ggttcaggtg ttgtgattct aaaaaataat gaagttataa
     8401 aaacttatag tgaaaaagga aaagaggaaa ctctagtagg tatgagaaat gtagctggag
     8461 agatagaagc ttctaaaatt gcaatgcagt actgtattga caataatgtt caaaacttga
     8521 ttttatattt tgactatgaa ggtattgaaa agtggtgtac tggagtttgg aaaacaaata
     8581 aagaaggaac tatagcatat aaaaattttt atgatagcat taagaataag cttaatgtaa
     8641 aatttacaaa ggttaaagct cattctggaa ataagtataa tgaagaagct gataaattag
     8701 ctaaaaaagc tattggtgta taataaaaaa atatttatac ataatgacat gctacaagag
     8761 tatatctaaa cccctaattt ataattaaat aaaatttgat ttaaaaagca gattatatta
     8821 tgagaaaata agtatctaat ttataaacaa ttaacatcag tgttaattag acacagctta
     8881 tttaatataa taaaatctgc ttttttatat aactataaaa tcttactaca ttctattaga
     8941 attgcccata aataccttca agttcttctt ttaatacctc agggtcattt ataccaatag
     9001 acatggttct agccaatata tttgcttggt cataagttga tgtccatgag aatacaccac
     9061 ctaaacaatt tctaagaacg tattgagttt ttaagaatat ggataaagaa tcatcatagg
     9121 ccattgcaaa ctctccatcc ttaactaaaa atgggacttg agcagtattg tcaaatctat
     9181 actcatatcc atttttattt atataatctc ttctaagttc atcataagtt cttgttatag
     9241 tagcacctaa tcttccataa aatggtatgc caagaagaat tttttcagaa ggcattccag
     9301 cattttcaag atttcttacc attgcatcaa cactatatcc tggtaaggat aaatcagaat
     9361 caaaaaggtt tgattgatgt tttctagcat ttggacctgt ttcacctgct gtaaaatcat
     9421 aactcataag attaaaataa tctattattg gagctatttt atctatttca gcacttgaat
     9481 ttatatatcc tctatctcct gttccagcta cactaagcca tttttcatct cctataacat
     9541 ctcttatagc tgttaataaa agtgtaaagt tttctctatc ttgaggtctt gatactattc
     9601 cagatgcact acttccagga tattcccagt ctatatctat tccatctaaa gcatattcat
     9661 ttatcatctg attaacctgt cttgcaaaat tatatctaga tgtaggtgtt aatgctgcat
     9721 cagagaatcc ttcagctccc caacctccaa tagctacaat tacttttaag ctaggttttt
     9781 cagctttaag agcaagtagt tggtttaaaa acctaggata aggaataaat aaatttccag
     9841 attggtctat ttcagcaaag gcaaatataa ccgcatccaa cagttgagca tctacattag
     9901 ttggatttcc aagaacatat tctgctacaa ttggatttat atctggacag tttgcatttt
     9961 caactattgg gttgtatggg tctgttattt gtggtctaac tagttttttt gaatctttta
    10021 aagttttcat agctattttt ttagtatttt tttcactagt ataatcgtag tttttataat
    10081 tgtgtttata gaaatattca taactactat catctttgtc atagctagaa tttattttat
    10141 cgcaagattc atctttgtca tagttaaact tcatttcatc acaagattta tctttaaact
    10201 tattttgttt ggaactgtga gttttgttag tatttttagt atgttttttc tcctggttgc
    10261 aatcatcttt aatatcagtc atgtgttctt gtttacagtc aagagctttg ttcatgtaat
    10321 catgatgttc atgttcacaa ttacattcat tttcaatgtt tttagtatgt tcttttttcc
    10381 agctacaagt attatcaatt ttcttgttca cttcttcagc attataatta tctggtacaa
    10441 aacataagta ccagtccata catgaatatt tcttattaca actgttaact ctatttttca
    10501 attccttata gtttttagga taaggtaaaa tcactggcat tccaggaaac cagtttgcag
    10561 gagtaactat attatctcta tcactagtct gaagtgcatc tactattcta agtatttctg
    10621 gaatatttct tcctgtagtt agtggataat aaagaattgt tcttagaatt tgattattat
    10681 ctataataaa tacagagcga acagttgatg tatcactcat tggttttgat atcatgccat
    10741 ataacttggc aattctcata tctctatctt ctataatagg aaatggaatt tctacacctg
    10801 taagtaaaga aatattatac atccaagcta aatgtgagct gttactatca acgcttagac
    10861 ctattagttc tgtatttctt tttttaaatt cgtcataata tttagcaaaa cataaaaatt
    10921 ctgtggtaca aactggtgta aaatcaccag gatgtgaaaa taaaacaatc caattaccct
    10981 tataatcaga gagtctaata gatccgtttg ttgtattggc tttaaaatca ggagcctttg
    11041 accctaaact tggcaaattt ggcatgtaaa tcacccctca ataaattatc atttatttta
    11101 ttctattaat taatacatat tagtgttact actttattaa aagttaagta atccttatgt
    11161 caaaaaaaga tatttattaa aaagatttaa tattttccta atataaatga caatagtaat
    11221 tgctattttt ttactaattt ggtatagtaa tggataagga gtagtgtcaa ttttagtgat
    11281 tatacgaggt gagtggattg aaaaaaattc taagaatttt agttatctcc atgatgatat
    11341 gttttgcaat gacttttgca ttagtattaa taaattcagt tatgggagtc catataggat
    11401 tggattatta ctttttgatg ggaagtgtgc ttacagtttg tttaacattt ggaattgttt
    11461 tatgcaatgc tagaaaaata tttgatagca aaactataca taaaacaaga atgaaaaatg
    11521 tcagtactaa taaaaaacaa aagagtcatt ctagagatat aaaaagaaag atatcataat
    11581 ttatgtaaag gaaatattta tgtataaaat aatgattgat aggtaaaata aaaacacgat
    11641 ttaacttgtg tttttatttt ttttcaagaa ttatgatata ataaccaata agaaatttag
    11701 tttaccataa aatataaaga ttattaaatg gagagggaac tataatgaat tttagagatt
    11761 tatttgagaa ggctgtagat tttattgatg aaaaaaggaa atctatagtt gcaatttcat
    11821 tatcaacatt aggtgtaatt gttttgatga tagtattttt cttaagtagt aacgagttta
    11881 gtgtaggaaa agaagctaat gagctgttaa agattataga aaaaagacag tattctatag
    11941 ctgttgatta ctacacaagt atagaaaaaa agttttctga ttcaaaaatg gaaagattta
    12001 ataagtctgt ttctaaaaaa ataaataaat tactattaaa tagtggtgat aaatatttag
    12061 atggagatat aagtcaagaa agctttattg gactaataaa tacagtgaaa gaattaaaaa
    12121 aaataagtat agatgtggac gacttattag ctcaagctga tagagttaga gaaatgtata
    12181 aagaagaaaa taccacttat gatattgcca ttaactacat aaacactgtt tcgctattaa
    12241 atggtatggg tagtaaccta gatgtataca aacagaatat agaaacaatt aaagagtcta
    12301 gagatgttta tgactcagca gtaaaagacc aaaaagtata taagtattat gaagctattg
    12361 aaaagtataa taaagtatta aaagaagatg agaagtatta cagtatggct caaaatggga
    12421 aagaacaatg tattgaagag atgtatgatt actatataag cagagctgaa gaggcaaata
    12481 cttctggaga ttatgaaaga gcattacaat atattgaata tttaaaagaa gattattcag
    12541 atgatgaaaa ggtgcagagt ttagaaaaaa aatataaaaa gaatttatca ttgtatactt
    12601 taacatctga tgacattata aatgtaatag ctaaaaaaag cggtaaagac aaggcaaatt
    12661 tatctataaa ctcacttcca cagatgataa aaaacaataa atactattat gctgaagtat
    12721 atgagtacga taaattaata aatgaagttt tggtaagtgc aaaaactaaa gatttatatt
    12781 cgtataaaga tgggaaaaaa gattacaaag tagattatgg tgatggatac tttagaatat
    12841 tagaagatgg aagttatcaa tttggtatta caaaagataa agctaaattt gtgttaacta
    12901 atgctcttga tgaaaaagaa aataagtata agaagattga gatattagat atagagaaag
    12961 ctgatagata ttcaaaaagt aaaaagagct tagaagaatt gtttggaaaa tataaaaata
    13021 tttattatta tgctgtagta aataaaggct tatttagagg aaaagaagtt tatgctatta
    13081 atatttacaa tgaaaaaata tatgctgtat cagaaaatgg actaaacgaa tattaattaa
    13141 taatattaaa ttaatatata attaaaaagt ttttggggtt ttaaggcgca ttatgtagta
    13201 atataataat agggatatgt aaataatttt attgtaagga gaagtatggg atgagtaata
    13261 tgaacaaaaa gctagttata gctattggag ctgtggcatt agtagcaata atttttatag
    13321 gcataatgtg catgcaattt aaaggggaga aaatagcaaa aaacacatat gttaatggag
    13381 taaatattgg aaaattaact aaatcgcaag caaaacagga attagctaaa aaatacaaat
    13441 tagagaatgt tgagtttaat tacaatgata aaagctggaa agtaaaaagc aaggatttaa
    13501 atttatctac tgacctggat aaaacagtag aaaacgcata taatttaaat agaaagagtg
    13561 gtttctttgg taatctatca aaaactattt cagcaaattt tggcaagaag agcaacttag
    13621 tagttgtggt aaattatgat aaaaataaat taaaagcaga aatgggaaaa atagctaaag
    13681 aaatagatgt agatgtaaaa gatgctacat tagatataag tggtgaaaaa gttaaggtta
    13741 taccagattc tgatggtctt aaaatggatg tttccaagag tatggagact tttgataatc
    13801 aaactaaaaa aggtaactat aaaaataagt tagcagtaaa agctactcca gcaaaagtaa
    13861 aaaaagagca acttgctaac atagatacaa acttaggtaa gtattcaaca acatttaaga
    13921 cttcccaaat aaatagaagt ataaacataa aattagcaac ggatagcata agtaatatat
    13981 tacttatgcc aggagaaact ttctcattta acgagcatac agggaaaaga agtaaggaaa
    14041 atgggtataa gagtgcacct gtaataatgg aaggtgagat ggaagaagat tatggtggag
    14101 gagtttgtca agtttcatct acattataca attctgtgtt atatgcaggt ctagaaattg
    14161 ctaatgtaaa aaatcatact ataccatcaa gctatgttcc aaaaggaaga gatgcaactg
    14221 ttgcagatag tggtatagat ttcttgttta aaaataatct aaagcatccg gtttacataa
    14281 aaaattacgt ttcaggaaat caaattgttt gtaacatata tggaagtgca gaagataaac
    14341 aaaatataac aatatcaaca aaattagatg gtgtttcaca gactacaatg aaaagagtta
    14401 atgaccctac aatgcctaaa ggtaaagaaa aagtagataa aagtggaaga aatgcatatt
    14461 ctgtatcaac atatagaaca tttaacgatg caaatggtaa gaaaattaaa actgaaaaaa
    14521 tagctaattc atattatcct aaaaaggaag gtattatatt agttggtact atggaaccaa
    14581 aaccagagga aaaaccaagt acagacgaaa ataagaataa tcaaaataca aacaatcaac
    14641 aaaaaccaga aacaccacca actgataata agcctaatga gacaccacca caaccgcaag
    14701 attaaagttc tcaagaatag gatttatgta gagtaataaa aaatataaat ctaaatagga
    14761 gggattactt tgaatttaaa taatataacg aattacgttc aaagtatttg cgagaatatt
    14821 tctaatgtct tggatgtaga tgttactttg gttacaaaag atttaactag gatagcaggt
    14881 acaggaatat tcaggggtaa aataggagag acaatatcag agaagtcagt gtactctctt
    14941 gttttaaaag atggaaaatc ctatgttata aataaggaaa tagaagagaa ctgtaataaa
    15001 tgtgcaaata gagaaaattg taaagagtta gctgatatat gtactcccgt taaaatggga
    15061 gagcatatac ttggaatctt gggtatagct gcgtttaatg aagaacaaaa agaaaagata
    15121 ctttcaaaag ataaggagtt aactgctttt gtaaggagta tgtctgattt aatatctttt
    15181 aaactagatg aactttataa acaagaagtt aaaactatag atgaccttga gagggaagct
    15241 atagaaaatg ctataaaaaa atatggaagc aacacagaag gaatgaaaaa agtagctgag
    15301 gcattgaata taggtatagc tacactctat agaaaagtaa aaaaattcaa cattaaaagt
    15361 taatagtatt gaaaaagagg taaccttttt atgaaaagaa gaggattacc ttttttatta
    15421 tgaaaatagt ggaaaaatat gtatagtttt gacttgacat attaaatatg ttatcttaaa
    15481 tatatatttt agagtggagg tgagtattat tttagttaaa gatataaaac aagatataga
    15541 aagcatgcct agaaaaattt tagatatatc tttgatagaa gataataaaa gtgatttaac
    15601 tttttttaat atagaagaag aagatggtga tgaaacatta aaagcattaa aacagagtta
    15661 tgtaactacg aattataaag aagaaacatt attaaacttg caaggagctt taaattcaaa
    15721 gtcagacaca acatctaagg agttaaaatt agaatcatat aaaagatata ataatgcatt
    15781 ggatttagca tataaaaatt atataactag tgccattaat atggtaaata aagctctaga
    15841 gataaatcct aaagacattg atatattaaa tcttagaggt cttttaaagt tattaaaatg
    15901 tgattttgcc aaagcatttg agagttttta tactgcttta tgttatgaaa ataatcatat
    15961 atctagaaag tatgtaaatc taatttcatc tgaagatttt aaaacttttt taggaagata
    16021 caatcattct ataagattta taaatgaaga attaaattat gagtcaatac atattctaga
    16081 gaacataatt gaagaagaac cagaactaat agaaccatat gtaattttat ctttgctata
    16141 tgataaacta ggtaatgtaa aaaagagaga gggatattta gacaaactta aagaattaga
    16201 taaagataat cctgtttttg aaaaaaatga agaagaaaaa gaagacataa gtaaaaatga
    16261 agaaacaaaa aaagtaaaaa gaaagaaaaa tattttacca tatattatag ttggttgtgt
    16321 tttaataggc atgggtttat atttaattca aagcaaaaaa agaatagaaa atttaaataa
    16381 tcaaataagt agcaaagaag aaaagttaag tgaaactgat aaaaagttag gggaaacgag
    16441 taaaaaatta gaaaaaacga ataaggaatt aaatgaggtt aaaaataaag aaccagaaag
    16501 aaagataact gtagctgatg aggaagattt atattatcaa gctctagatt taaagaaaaa
    16561 gaaagaatat gaaaaagcta tagaaaattt caaaagtata gtttcttctg gaaaaactaa
    16621 aaaatatatt tctgaatcaa tatatcaatt agcaataaca aataagttat tgggaaataa
    16681 ggatgaagct ataaaatatt acaaaaaata tataaatact tatactaaaa atgaccagta
    16741 ttatgatgat tcatattacg agttgggtat gctttattat gataatggcg atttaaaaaa
    16801 tgcacaacag actttttata gtttgagaag tgaagttcca gacagtatgt ataacaattc
    16861 aaaaataaaa gaaattttaa gtgaaaaata ggtttatata gttaagtttt ttgaaacaac
    16921 caagtatgta ttttattaaa ttaaaataaa aataaattta aaaagagatt gtatcaaatt
    16981 ataactttct attttaaaga aagatatttg cttgttgata aaactacaaa tatatgattt
    17041 gaagcaatct ctttagtttt tggaggtgga aaatgaaagt tttcaatcaa ttagtaataa
    17101 ttttatctat ctgggtaata ggagagtata taagttcctt tatacaagga attatactta
    17161 ttcctgggag tatagttggt atgctgctat tatttctact attacaattt aaagttttag
    17221 atttgagtag tatagaaaat gtaagtggat ttttcctcga taatatggct atatttttta
    17281 ttccagcagg tgtatcactt ataaagtcat tagatttaat aagggaaaat gtattagtac
    17341 ttttattagt catatgttta agtacactaa tagtaatgta tactactgga attatagtgg
    17401 aaaagatgat aaaaaagaag gaagaaggac aaaaaaatgt ataatgtatt gcacacgcca
    17461 gtatttggta taatagtaac aatagtattt tttaatttag gaagatatat tcaaagaaaa
    17521 acaagtaatc ctatatgtaa tcctctatta attgcaatca taggaataat attattttta
    17581 agtatatcta aaattcctta tgagaattat aagatagggg cagatagtct aaatttcttt
    17641 ttaggtcctg tcacagtagt gcttgcagtt ccgctttata aacaatttga actatttaaa
    17701 aagcatatgt ttgagatcat tgcgggaata ggttgtggta tagtgatttc ttttgtatct
    17761 gtattgataa ttggcaaaat agctaattca gatgtaagta taataaattc actgattcca
    17821 aaatctataa caacaccaat gggaatatct ttagcaaatt ctttaaatgg tatagaatca
    17881 ataacagttg tagccataat ttttacaggt atttttggcg gtatgattgc ttctacagta
    17941 ttcaaacttg ggaatataaa tcatccagtt gctaaaggaa ttgctcttgg aacgtctgca
    18001 catgctttag gaaccacaaa agcttttgaa tttggagaaa tagagggagc tatgagtggt
    18061 gtttctattg gagtttctgg tacaattaca gtaatactaa ttccaattat aatgaatttt
    18121 atataaaaaa taaaattaag ataagtatct tgaatactta aaacaaaata aaataaaaaa
    18181 aatttaaaat aaaaactgaa agaaaaaaat gcaaataatg aaataaaaaa atcatacact
    18241 gaaattataa aaacaaaaat ttcatttagg aattaattgt aaagatataa ttattaaatt
    18301 caaatttgct aaaataaaat aaattactgc taaaatggat atttagaaaa aaatactata
    18361 aatttactat attgcaagtt aaataataag tagtatcata ctatgctaga aaaagtttca
    18421 tttaaagcat aaatgagatg atttgaacgt ttttaaagat tggaatataa aagattacac
    18481 tagacatata tgaaaaagat aatataatag atgatgtaat agatgacagt tcaagaaatt
    18541 atataaaaaa tttatttgaa atattatcta ttacatcagg aataatatat gtaagagtaa
    18601 gcttttaaaa ttctaaggat ttagaaagat tgaagggaga aagaaatgag tgaagttaag
    18661 aataccctac aaaaacatcc agttttaaga tattcaacaa tgctatttgg gatgttgatg
    18721 acatctatag gaataaatgg gttcttaaga ccagcacatc tacttagtgg aggtgctaca
    18781 ggtatagcaa catctataaa ctatttgacc aatataaatg taggtttatt aacattttta
    18841 atcaatattc caatatttat cttagggttt atatacctag aaaaagagtt ttgtatttca
    18901 agtttggtaa atatgattgt attttcatta ttattaggtg caactcagga aataagtaag
    18961 attataccta tacatgatat attgcttcaa agtgtatatg gaggtatatt atctggttta
    19021 ggggttggaa ttgtatttag aactaggtct tctcaaggtg gtacagatat aatagctgca
    19081 atactaaaaa ttaagaagaa tatagaaatg aaagacactg ccttagcaat aaatggcttg
    19141 atagtactta caggaagttt tttatttggg ttagatttag cattatacac tcttataggt
    19201 ctatttctaa atgcgtattc aatgagtttt attaaagatg caatgaatta ccaaaaatct
    19261 gttatggtaa tgtcagatga agtcgattta atagcagaag atataatgaa gagtttagtt
    19321 agaggtgtaa cttttttaga tgcagaaggt gcatatactc atcaaaaaaa gaagattata
    19381 tatacaatag tttcatcaaa tgagatacca aagataaaag acatagcttt gaagtatgat
    19441 aaaaaggctt ttatatctgt aaatgatgtt acagaagtaa aaggaagagg gtttaaagca
    19501 aaagacttat agaaaatttt aaaagctggg agtttgtaat gtaaatttgt acattatatc
    19561 tctcagctta tttaaattta gtatatgaaa ataaaggttt tattattgat ttgtgtatca
    19621 ctttaaaaca tatcatttta aaattaaaat tgaaaaaatc actcaatatg tagaaaacat
    19681 gaccactatt aggatataat aaatttaata gatttagtaa aatatctagg aataacgttg
    19741 gaggaatggc attatgaatt tatctaaaga atatgttaat ttgtatgata attatttgaa
    19801 atatataaat gaagtaagca aagagattag aagtataaag agtatgaaaa aacgtgtttt
    19861 aaaaagggga gattttgctc cagaaaatga agtattagaa ttggaaggaa aaacaatacg
    19921 tgatatagat gatgtagata caaaaaaacc gaaaaataaa atatataaat tttcaaatgg
    19981 ggatgtatat atagggaaat tcttagaggg aaagatggag gggaaaggct catatacttt
    20041 ttttgtagat gaaggaacgg ctatggagta cataggagaa tttaaagaag acaaaaaaaa
    20101 cggaaaagga aactttgtat tttcaaatgg aaatgaatat ataggctatt ttgaggaaga
    20161 tatgatgaat ggtattggaa atatgttata taatagcaaa gatgaatata ttggaacttg
    20221 gaaaaatgga aaaaaagatg gaaaaggtat ttataagtgg agtgatggat gtatatatgc
    20281 aggtgaattt aaaggtggga agatggaagg atatggcatc tgttataata gtaaaggtga
    20341 aatcctttat gaaggagaat ggaagaataa tttgattcat ggtaagggaa cttatatatg
    20401 ggaaaaaggt aaaaaatata taggtgaatt tatgcatggt aaaaaacatg ggcaaggaac
    20461 tttttatcta aataatgaat tggtttatga agggacttgg aaatttgata agccatctat
    20521 atttgataga acattagatg aaatattttc cttgaggctg tagctttatc taattagata
    20581 aagctttttt ctaatactta ctgtaaatag gtatgaatga tattgattag tatacactat
    20641 caatattagc ctaataaatg taatattaaa aaattttgat tgattttaaa aaggagagat
    20701 atattgaaga aattaattgc tttagtgtta gtaatactta ttgttttatt ttatagccct
    20761 gaattgttaa aagaaggaaa tgatttaaaa gaaaagtttt ttcaaagtga aatatggaat
    20821 gaatttttag ataaaataaa tataaatgat aattctaaga aagataaaaa agaaaaaaat
    20881 caaaatgtac aatcaaataa tactgaaggg gataatttag gagagtcaga cataaagaat
    20941 tttgaaaaaa taagtttaga agacaattta agctatgttt tatcaagtat tggtaaacct
    21001 ggtagaattg atactagtga atatggtttt gattggtatg tatataatca atatggaaaa
    21061 gaatttgcaa tggttggagt tgaaaatgat gaagtagtag cactttatag caattctatt
    21121 aattcatctg aaaatcaagg tataaaaata aatcaagata gacagacagt gagaactaag
    21181 attacaccgt taaagtataa gagaaaagga aataccagat atataataaa ctcagaaaat
    21241 caatatgata taataagtaa agaaggtaag tacattacaa ttttctacga tattcatgaa
    21301 aaaaatagag tttgttcata tttaataatt gataaaagta ccgaagatga gtttaaaaaa
    21361 ttatatccag atgatagaga agagcttaaa aaatgttttg aacttgaagt tatagacctt
    21421 gtaaatagtg ttagaaatca aagaggatta aattcactga gatacagtga acaggcaact
    21481 ttgagttcaa gaaaacatag tgaagatatg agagataata atttttttga ccatgtaaac
    21541 aagaagaatg aaactccatt tgacagaatg aaaagagaag ggatagtata tacttcagct
    21601 ggagaaaaca tagcagcagg acagattaat gcaatatatg cacatgaagc ttggatgaac
    21661 tctgaaggac atagaaaaaa tattttgggg aattataata atattggagt tggagtaata
    21721 tttggaggaa gctataaaac atattacact caaaattttt ataaataact aaaatatttg
    21781 aaaggaagtt taaaaatgac atcatggaaa aaaaagacag tatataagtg tttaatagca
    21841 gtagtcttgt tttgtggaat aatattaata tctaatttta gcaaagtttc tgctttgatg
    21901 acggatacta gtggaaatgt tttgattaaa catggttcaa gagaaaaaaa gttaatagca
    21961 attacctttg atgatggtcc tcatcctaaa gaaactagtc aagttttaga tgtgttaaag
    22021 aaatacaatg taaaagctac cttttttata gctggaaaac atgcaaaatg gtataaagaa
    22081 ccattagtaa gagcaagtaa agaaggtcac gagataggaa atcatacttt caatcatcct
    22141 gatataagta atttaagttc tagtcagata gaagaggaga ttgttaagtg tgaagacatt
    22201 ttgaaagaag taactggaaa aaaacctaca ttatttagac caccatttgg aagttataga
    22261 gaaaaagaat taatagaaat tgcaaagaag catgactata aagttgtttt atggacaggc
    22321 gtagatgtga aagattggaa aaatccagga gctaatagca ttgcagataa aataattaat
    22381 aaagtacaaa atggagatat aatactttta catgattatg caactaatga tacagttgaa
    22441 gctttagata tgtttatccc aaaaatgatt gaaaaaggct tcaaatttgt aacagtttct
    22501 gagttaataa aataattttt agggggagat ttacagtatg attcttatga tagacaatta
    22561 tgattctttt gtatacaacc tagtacaata tatagaagaa ttaggggaaa cagttgtagt
    22621 aaaaagaaat aatgaaatta aaataaggga cattgaagag ctaaatccag aggtaattgt
    22681 gttatctcca ggaccatgct ctccaaaaga agctggtatt tgtatagata ttgttgagta
    22741 ttttaagggg aaaaaaccta tactaggaat ttgtttaggt caccaaacta ttggacatgt
    22801 ttttggagga gatattataa aagctcaaca gcctgtgcat ggaaaagtat atagtattag
    22861 tcatactaat aaaggagttt ttagggggct taaaaaccct ttaaatgtaa ctaggtatca
    22921 ttcactaata attgattcca atacagttcc aaaagaacta gaagttacag ccactactga
    22981 taaaggggaa ataatgggaa ttagacataa gaaatattta atagaaggag tacagtttca
    23041 tccagaagct attttgtcag agtatggtca tgaaatgctt aaaaacttta taatagaagc
    23101 tagagaaagg gtacatatgt aatatgataa gagagataaa tactacacta aattcttttg
    23161 agatatttac tatttttaga aatgaacatg acagttttat attagacagt gctatggata
    23221 aagaaaaatt gggaagatat tcttttataa gtagccaacc attcaaggta ttaaaatata
    23281 aggatactga tgaaaatcct ttagaagttt taaaagaaga actacataaa tatagagtta
    23341 taaatgacac taatcttcca tttgtaggag gtgctgtggg atatttatcc tatgatttag
    23401 gtaattacat agaaacttta cctagaactg ctatagatga tattaagatg cctgatatgt
    23461 attttggatt ttataatcat gtaatagtta tagaccatct tgtgcaaaaa acttatatag
    23521 ctactccaaa catagatata aaattagaag aaaagataat ggatgatata gaacaaagaa
    23581 tattaaaaga agaaaaaaaa ggcatagata gtatatgtta tgaagaaaaa gaagtaacac
    23641 ctataagact taaatctaac tttacaaagg aagaatttaa aaatgcagtt caaagtgtta
    23701 gagagtacat aagacaagga gatatatatc aagctaattt aacacaaaga ttcagtggag
    23761 aaacagaact tacaagcttt gaattgtata gggatctaag aagatttagc ccagctccat
    23821 ttggagcatt cttaaatttt gaagacacac atatattatc aaattctcca gaaagattta
    23881 taagatgtgt taataataga atagaaacta gaccaataaa aggtactcgt ccaagaggta
    23941 aaaataaaga agaagattta aaacttcaac aagaacttag aaatagtgaa aaagacagag
    24001 ctgaactgct tatgatagta gatttagaaa gaaatgatat tggaagaata tctaaaactg
    24061 gaagtgttaa agttccagaa ctatttgtaa ttgaaccata tgcaaatgta aatcacttag
    24121 tttccacagt tgtaggtgag ttaaaagatg gcaaagatgc tactgatgta ataaaagcaa
    24181 cttttccagg ggggtctata acaggagcac ctaagattag agcaatggaa attatagatg
    24241 aattagagcc aacacaaaga aatgtatata ctggttcaat aggttatata ggttttaatg
    24301 gtgatatgga ttttaatata gcaattagaa caataatcaa aaatgacaaa aaagtctatt
    24361 ttcaagttgg aggaggtatg acttgggatt ctgacccaga tgaagaatat caagaaacac
    24421 ttgataaagc aaaatctata atgaaggctt tgaggggata ttatgaagaa taatgtaggt
    24481 tttgatagta gtttaagtaa atttggaatt ggtttgtttg aaactattaa agttaaaaat
    24541 ggattaccaa tagatttaaa tatccatgta gaaagaatgc taagttcaat aaattgtttg
    24601 gatttagata taaattataa aaaagatttc ttgataaatg aaattgttac atatataaaa
    24661 aaagaaaatg ttattgataa agcacttaga attaccgttt ttgatgaagg ttataatata
    24721 tctattaggg atattccata taatcaagag atgtatgaaa aggggtttag attaactata
    24781 tcaccgatag ttagggggaa tagtttaatt catagacata agactactaa ctattttgaa
    24841 aatatatata ccaaaaatat cgcaaataag actggttata atgatggtat atttttaaac
    24901 tcagaaggtg taatattaga atgttctatg agcaatatct tctttataaa aggagaaaga
    24961 gtgtacactc ctagtgatag attgccaata ttaaatggaa taataaaaaa aaggattata
    25021 gagatttgtg acgaattaca tatagagttg atagaaaatg aaattaatat atcagaaatt
    25081 agtagttttg attttgtttt tgtcacaaat agtcttatgg gcgctataaa ggttacagaa
    25141 attgacaaaa taaaatttaa taaagaaaat gttgtttttg ataaaataga ggagttatta
    25201 gaataaatta aaatattaac aatttgttgg agacaaaaga tgataggctg tatttatgaa
    25261 gtatacaatg aagagataag taaaataata gaaaaccaaa atactttggc tgtatatttg
    25321 gtgggttcta gtaaagatgt agattttact ctttatgatg tagaaataaa cgatattgat
    25381 gtattcgttt ttgtaaaaga aggggaaaaa caagagagaa tactatttaa aaaaaaggga
    25441 atagaatttg atataaatta cttttcaaaa gatggtataa aaaaattatt atcaaatagg
    25501 gaatactttt ttgtgaaaga aatgaaagat gctaaagtac tgtttgatag ggaaaatata
    25561 tcacatacta taaaagatat aagtagagat atttacttag aaggacctag taaaatgtca
    25621 ttagaggaaa agtcttttat aaagcaagat attggagcaa aaatatcgaa tttaaaaaat
    25681 aaagaaaaat ttgatgtttt tgaatatcat tttttgacga atttatattt aaaagatata
    25741 ataattgggt actttaatat aaatgataaa tgggtaccaa aagataaaaa attgctaaaa
    25801 gttttaaaaa aagaaaataa tgagcttttt gaactagtgt caaaagtaag tgaaaattat
    25861 gactatcaaa gacttttaga tgtttataat tatattttta aagaaattga gacaaaagag
    25921 gttataaaac taatcttcta gtcacaaatc aatgggggga gtttaaatga ataaagttga
    25981 taaagaaaag atacaacatg cagtaagaga aatattagag gcaattgggg aagacccaga
    26041 tagagaaggt ctaatcgaga ctccaaatag agttgctagg atgtatgaag agatattctc
    26101 tggtcttaat gaagaaccaa gagaccattt aaaagttctt tttgcagatg aaaaacatga
    26161 agaattagtg ttggtaaaag atattccatt ttattcgtgc tgtgagcatc atctagttcc
    26221 tttctttgga aaggctcata ttgcttactt accaaaagga ggaagactta caggtctttc
    26281 taaacttgct agagtaatag atacattggc aaaaagaccg caattacaag aacgaatcac
    26341 taaaaatgct gcagatataa taatggaaga attacaacct tatggtgtct tagtagtagt
    26401 agaagctgaa catatgtgca tgacaatgag aggtgtaaaa aaaccaggtt caaaaactgt
    26461 tacatcagca gtgagaggta tatttgaaaa ggacattgcg tctagagctg aagctatgag
    26521 tttgattact atgaagtagc aatttattat atatagaatc atttattgag atatgaaatt
    26581 taatttaagg gagtgtcatt aattgtgttt gattatggta aaagaactta tataatggga
    26641 atattaaatg taactccaga tagtttttct gatggaggag attttaataa cttagacata
    26701 gcaatacaac atgcaaaaga catggttgac caaggtgcag atataataga cttaggagga
    26761 gagtctacac gtccaggtca tagctatgtg gattcagatg aagagttaag aagagtaatc
    26821 cctgtaataa aaaaacttaa acaggaattg gatataccaa tatcaataga cacttataag
    26881 gcagatgttg cagaagaagc cttaaaacta ggtgttacta tggtaaatga tgtttggggt
    26941 cttagaaaag ataaaaatat ggcttctgta ataggaaaat atgatgcaga agtgtgtata
    27001 atgcataatc aagatgggac aaactatgac aaagatataa tggagtcaat aaaagatttt
    27061 tttaagataa gtatagaaat ggcaataagt tgtggtgtaa aaaaagaaaa aatagtactt
    27121 gacccaggta taggatttgg caaggatttt gaacaaaata ttgaagtatt aagaagatta
    27181 aatgaattaa aagatttagg gtatcctatt ttgcttggga catctagaaa atcagtaata
    27241 ggaaaagtac ttccagttga gcctaaaaaa aggttagaag gtacaatagc tactactgtt
    27301 cttggtataa gagatggtgt agatatagtt agagtacatg acgtttatga aaatttaatg
    27361 gcagctagaa tgactgatgc aatatataga aagtaggtat aatataatgg ataaaatatt
    27421 acttagtaat ttaggattct atggatatca tggtgttctt aaagaagaaa attttctagg
    27481 tcagaaattc tttgttgaca tggaacttta tattgattca agagaagcag gtcttagtga
    27541 cgatataaat aaatctgtaa gctatgctga ggtttacgat gttgttaaag atattactga
    27601 aaataaacaa tttaatcttt tggaggcttt ggcagaaaat attgctgaag aagtcttgaa
    27661 taaatttata cttataaatg gagttatggt cagagttaga aagcctgaag ctcctgtaaa
    27721 tggtatttat gactattttg gtgttgagat aaggagaaca agagatgaat aaggcttatt
    27781 tgggaatagg tactaacatg ggtgatagat ttgataattt atcaagagca tgtgaacttt
    27841 tgaaaaacag cgattctata tataaggtaa aagaatcaag tttatacgaa acaaaaccat
    27901 ggggttatac agaacaagca gattttctaa atatgtgtgt agaaatagaa acagagtttg
    27961 agccttatga gttgttagaa tattgtcaag aaatagagag aaaactacac agagaaagaa
    28021 tagttcattg gggaccaaga actatagatg tagatatact attttttaat gatgtagttt
    28081 ccactgatga aagactaata atacctcacc caaggattca agatagagct ttcgttttga
    28141 taccacttat ggatttaaat gaagaactta taataaatga aaaaacaata aaagaacatt
    28201 taaacctcct atctgctgaa gaaagagatg aagtaaagga gcttgtaggt tatgaaagaa
    28261 aacctattta ataataattc aaagatagag ataaacacaa ataacaaaaa gataactgta
    28321 aaaaaggata aacttataat agctggacca tgtgcaatag agagttatga gcaacttttg
    28381 gagacggcta aatttgtaaa aagtcaggga gcaaatattt taagaggtgg agcgtacaag
    28441 ccaagaacat caccaaattc atttcaagga ttaaaaaaag aaggtcttga aatattaaaa
    28501 gcggttaaag atgaagttgg tatggctgtt attacagaac ttatggatgt aagagatatg
    28561 gacgaattgt atagtataag tgatataatt caaattgggt caagaaatat gcaaaacttt
    28621 actcttttaa gtgaagtggg aaaacaaaat aaacctgtta tgttaaaaag aggaatagca
    28681 tccacaatta ctgaatggat aggtgcttct gaatatatag caatagaagg aaatagtaat
    28741 attataatgt gtgagagagg tataagaaca tataatgatt atactagaaa tacattggat
    28801 ttagctgcag tacccattat tcaaaaggaa acaggtcttc ctgttgtggt agacccaagt
    28861 catgctactg gagttaggta tttggtaaaa cctatgtcac tggcatcttt tgcatgtgga
    28921 gcagatggaa taatggtaga agtgcatcct gacccagaaa atgctttgtc agatggtgct
    28981 caatctcttt gttttaatga atttgaagat ttaatgaaat caattaataa ttattaaaag
    29041 aggcatgagc ctctttttta ttcgtaatcg ttattaaggt aaatttataa gttataattt
    29101 gatggttata ttatttatta taaataaaga tttaatattg atagaattaa tataaaaaat
    29161 aaaaattttt tgattaataa gaaggatatc aataaaaaaa gtcgaattgt gtatattgag
    29221 tgattgacaa atttagaata tagtgtagaa tagaaatgtt aacacaaaaa attacaccag
    29281 aaggtgataa tatgaatgat ataaaagaca ttattgaaga aataaaagct agatgcgata
    29341 tagcaagtat aatatctgaa tatatgagta taaaacaatc tggagctaat tacaaaggat
    29401 tatgcccatt tcatggcgaa aagacaccat ctttttatat aaatacatca aaacagattt
    29461 ataagtgttt cggttgtggt gaaggtggag atataataaa ttttgtcatg aaaatggaaa
    29521 atttagattt tatggatgct gtaaaaattt tagcaaataa atgcggtata gaaattaaca
    29581 ctaacatgaa tgaagaaact agaattaaaa tagaaaaatc taagaaattt caagatattc
    29641 acacagaagc agctagattt tatctttcaa acttattggg aagcaaaaat cttgggtatg
    29701 aatatttaag aataagagga ctagatgata aaattattaa gaagtttggt ttaggatttt
    29761 ctttagattc atggaattca cttatgaata ctctaatcag taaaggatat aaaaaacaag
    29821 acttattgga gtgcggtcta attgcaaaaa atagagatgg aactaattgc tatgataaat
    29881 ttaggaatag agttatgttt cctatattcg attatagagg aaacataata gggtttgggg
    29941 gaagagtatt agacgattct ttgccaaaat acttaaattc tccagacaca ttaattttta
    30001 ataaaaaaca gaacttatac ggattaaatt ttgctagaaa aaatttagaa agtaaaacta
    30061 tagtcttagt tgaaggatat atggatttaa tttcgcttta tcagtatggt ataaaaaatg
    30121 tagtagcaac ccttggaaca gccttgactg aacaacaagg ccttttaata aagagatatg
    30181 cggacactgc tattatatct tatgattctg atgaagcagg aataaaagcg actttaagag
    30241 ctatagacat acttactaaa ttaggtatca atgtaaaagt gttggactta aaagatgcta
    30301 aagacccaga tgaatttgta agaaaatacg gacttagtga ttataaaaaa gctatggatg
    30361 tttctactca ctacataaaa tataaaatag atcatcttaa aaaagaattt aatattcaaa
    30421 aagatgaaga acgagtgaag ttcgcaaaag aagcttctaa aattataaaa caattgacaa
    30481 gtcctgttga aattgatttt tatacaaagt atttaagcaa tcaaatagat attaatgtcg
    30541 agtctataaa gagagaagtc tatggtaaaa attacaataa gccatataat aacaaaaatc
    30601 aaaagaaaat agaagaaaaa gtaattgaaa aagtcgaagt cagacaagac ggaaaacaat
    30661 tagttgaaga aactctaata aaaataatgt tagaagacaa aaaaattaga gaaatagcgt
    30721 tacttaaagt agaagaaagt gattttttat tgaaagaaag taaagaaatt ttaaattaca
    30781 tgattaaaaa tcaagaattg gacaaaataa ctattgacaa attgaaaagt ttaaacatat
    30841 ccgaagaata cttaaaagaa ttaaattcaa tttctttgaa tagtataaac ttagagaata
    30901 caaaagaaat agaaggaata ataacaaata tcagaaaaaa ctcattagaa gagcaaatta
    30961 atagcttgtt gagagaacaa caagaattag aaaataataa tgatatgaaa gaggtagatg
    31021 gtagagttat ggaaattgct ttaaaaatag ttgagataaa taaaatttta aagagcttgt
    31081 agagaaagga ggtttgagtg tggaaaataa atcgaataaa aaagagttaa aaaaggttac
    31141 tgctaagaca ttaatagaaa aaggaaaaaa gcaaggttct ctgacacttg cagagataat
    31201 ggaagctttt tcggagactg aacttgataa ggatcaagta gaaaatcttt atgagacttt
    31261 gggaaatttg ggaatagaaa taacagaaac aaaaaattat aaagctgata tagatttttc
    31321 ggttgctgat gacgatttaa gtataggcca cttagatgaa gatgcagaag caatttcaca
    31381 tgaggactct tctgcaatag aaatagaaac tgtggattta tctttaccaa aagggataag
    31441 tatagatgac cctgtaagaa tgtacttaaa agaaatagga aaaattcctc tacttaaacc
    31501 acatgaagaa gtagaatttg ctagaagaat gcacgaaggt gatgagatag caaaacaaag
    31561 gttagttgaa gcaaacttaa ggctagttgt aagtatagca aaaagatatg taggaagagg
    31621 tatgcttttc ttagatttaa tacaagaggg aaatttaggt cttataaaag cagtcgaaaa
    31681 atttgactac acaaaaggat ataagtttag tacttacgca acatggtgga taagacaagc
    31741 tataacacgt gctattgcag accaagctag aactataaga ataccagttc atatggtaga
    31801 gactataaat aagctaataa gagtatcaag acaactactt caagaacttg gaagagatcc
    31861 aaagccagaa gaaattgcaa aagaaatgga aatgacagaa gacaaagtaa gagaaataat
    31921 gaaaatagct caagaccctg tgtctttaga aacaccaata ggagaagaag aagatagtca
    31981 tttaggtgat tttattccag atgatgatgc tccagcccca gcagaggcag cagcatattc
    32041 tttattaaaa gaacaaatag aagatgtact tggttcatta aatgatagag agcaaaaagt
    32101 attaaagctt agatttggac ttgaggatgg tagagctaga actcttgagg aagttggaaa
    32161 agagtttgat gtaactagag agagaataag acaaatagaa gcaaaagcat taagaaaact
    32221 aagacatcca agtagatcaa aaaaacttag agattattta gactaaaaag atacatcatt
    32281 aatgtttttg tgataaatgc catgagataa gtgatatctc atggctattt tgtagtaaag
    32341 atttaatttt ggttttgtag ttatttcagt cttatctata acttagttaa attatatgga
    32401 taaagtgaat tgaaaggaga attatatttg aaattaacag atagattatt gaaaatagca
    32461 tcattggtgt cagatggaaa aaaaatagct gatataggaa cagaccatgg atacatacca
    32521 gtatatttgt taaaagaggg aagagtacca tttgcagtgt tggcagacgt taataaagga
    32581 cctcttgaca atgcccataa agaagtcata cagaacaatc ttttagataa agttgattta
    32641 cgattgggtt ctggcataga gattcttgaa ataggagaag tagaagaagt aataattgct
    32701 ggtatgggtg gaattttgat aagtgagctt ctcgaagcta aaaaagaagt agcacataat
    32761 gtagaaaaat taatattaca gccaatgcaa gcgcaagaag aacttagata ttacctttta
    32821 aacaatggtt atgaaatttt agaagaagtt ttagtgagag aagattttag aatatatgaa
    32881 ataattgttg ccaaatatac aggtaaaaat actataatag aagatgagat atattatgag
    32941 gttggaataa agcttttaga aaacaaggat tctcttttta aggattttat agaaaaaaag
    33001 ataaagacat atagttctat agttagcaaa ttagaaggga aaaatgggga agctatagat
    33061 aagaagagaa atgaaagtga agttacgata aaaaaacttg aaaatttaat aaaataaata
    33121 ggaggaatat atgctattaa agagtctaac tagaaaaatt gaaaaaaaat accctctaaa
    33181 cttagctgag gattgggata atgtaggtct tatagttgga gattttgata tggatgtaaa
    33241 aaaggtattg gtatctttag aagctaatga agatgttatt gatgaagcta tatctaaaaa
    33301 tatagattta attgtgacac atcatccttt tatatttggg aaaattaata aaattaatag
    33361 tgcagattta aaaggtaggc ttatccaaaa acttattaaa aataatgtat cactttattc
    33421 tatgcatact aattttgata tagcatttga tggtttaaat gactatttta tggaaattat
    33481 ggaatttggt aattcaaagg ttttagacgt aactaaaagc gaaaacttat ataaattagc
    33541 agtatacgtg ccacataact attcagatga acttagaaag gttttaagta attcaggagc
    33601 aggtcatata ggaaattata gtgactgtac gttttcaata gaaggtgaag gacaatttaa
    33661 gccattagaa ggctctaatc cgtttcttgg gagtgtaaat gatatagaaa ctgtaaatga
    33721 agttaaaatt gaaactgtag taccacagaa gctcttaggt ggggtaataa gttctatgtt
    33781 agatgcacat ccttatgaag aagttgcata tgatttgtac aagttagaaa ataaaggtga
    33841 gatatttgga ctaggtagaa taagtaaact tgataaaagt atgacattag aaagtctttc
    33901 aaagaaaata aaagagaaat taaatatgaa acacatcaga gtagttggaa atcttagtac
    33961 aaacataacg aaagtagctg ttgtaacagg agctggttca gagtttgtaa aaaaagctaa
    34021 gagacaaggt gcagaagtac taattacagg tgatgtaaag tatcatgagg cacaagatgc
    34081 acttgatatt ggtatgtgta tagtggattg tggtcatttt gatacagaag atatatttaa
    34141 aaatgttatg aagagatttt tagatgaaat tagtgaaatt gaagtaataa aaagtagtgt
    34201 atatttgaat ccatttagta ctatttagta gtacttgatt aaaaaatagt atataaaaaa
    34261 taaatttgag tttaattagg gggataagga tgaaagcagc agtaattttt catagtgttt
    34321 gtgggagtac atacttatta gctagagaat ataaagaagc gcttaaagaa atgaatattg
    34381 aggtagatat ctttagagta agtgacgaag ttgcaaagac acttcctcaa tattatttaa
    34441 taaattctaa agaatacaaa gatgaatttg aaagtataaa tgtaattaaa tctggaagag
    34501 agctattaga ttatgatgct atatttatgg gttcaccaac atattacgga aatgtatctg
    34561 gaccaatgaa gatgtttatg gatagttttt ctgatatttg ggtaggtgct cctttgagtg
    34621 gtaaaatatt tggttgtttt gctacagcag gttcacaaca tggaggagga gaactagcct
    34681 tgcaagctat gaatatattt gctcaacata tggggatgac tcttttatca gttccatgtt
    34741 caataagagg aggtcatcca gcgtatggga tacttcatat agcaggagat aactctaata
    34801 taagaccaag tgatgatgtt aaaataggta taagagatta cctagaaaga cttagtatat
    34861 aagaatacta tataaaaata cctaaaagtg gctgtatata cttttaggta tttttactta
    34921 attataaacg tgaagcttta ccagaaatat ggtcaatttc tattttaaca acagttgtta
    34981 agttcacatc tttctctatg tacttcatgc cttcttcaaa gaatccttta gaatattttt
    35041 ttattatttc tacaagagca tttttctttt cttcattttc tacagtacaa gctttcccaa
    35101 aaactatagc actagaataa gtagtactaa atttgtctgg aataacattt tcattagcaa
    35161 ccactaaaaa agaaactttg ttgtttttca atatattatc taacttatga ccatttcttg
    35221 cagagtgaaa gtagatagaa tcatcaaagt atacataatt tacagcaact ccataaggat
    35281 aaccattttc agatatagtg gaaaaagtac caaattcacc attttttaat acttcgatag
    35341 tatcttcttt tgtcatttct cttttcttca atctcatttc tttaaacata atatcatcct
    35401 ttctaatttt gatgcttaaa ttaaatttta gagcatatat aaatattatg ctatgttttt
    35461 tataaatttt aataagaaaa tatagtttaa gataaaaggt tgagaaagag aatctatttg
    35521 ggggttcatt tatgtaatta ttgttagagt attaccaaca atattaataa ctttaattaa
    35581 tgacttgctg ttatttaagg tagcaagctt gtctataaga agggaaagtt atcgaggata
    35641 gaagttatag tttataatga tattataaag aaaatgttgt tgtagaaaat aataaatagt
    35701 agagaggtat taagttgaat ataatactta atacctcttt aaaattaaat tataaaagtg
    35761 ttatggaaac tgtactatac atggtaagga gataataaag aatgtatctt taaagtctca
    35821 accaaacagc aaaacttatc caacaaacat acaataaatg cttctttgta tctaggaggc
    35881 ttgacagtaa gtggccacat gtgctttaag attatgtccg tttctttttc atttatttga
    35941 aaaaataaag ttgcattttt caatgcttct ctagggtgag taaatccatg taatcctttt
    36001 ctatcacctt tgtaatgcca atcataaaga aaaaagtcgt gtaataaagc ccctctaata
    36061 acactttgaa tatcaacatt tagatgcaat tttttacata atagataact ataatatgct
    36121 actgataaac tatgttcaag acatgaaaca ttgccatgat gaggaaatgt tctcataagt
    36181 tgtacttttt ctgaagaaag tatttcagaa gcacattcat taaaatattt gatttcagct
    36241 tttgacaaca ttatacaaat ctccatttct agtaatataa atactatatt tcaacgatat
    36301 atgaaatatt tcttatccta caaaatataa tacccaataa tacaagtaag atacctttta
    36361 tggtatttta aagtaagaga gattttataa ggctaaacaa taaaaaaatt aaaagtaaag
    36421 ctatagcaat atatagtatt tttccaagag gattgccaaa atttatagtc catccaatac
    36481 caaacctttt attaaccatc aatgatgggt catttggatt attatacatg attcccgcta
    36541 tccaatattt ttcattctct tctggagaat aagaagagtt cgattttaaa tttggagaat
    36601 taatgtatgt tgctattaaa taaattataa ctaaaagcgt tgtaatattc atagcagttg
    36661 atagttttgt tttaattgat aaaatagtag taaaaaactg tattgtcatt atagtcatca
    36721 atattaaaaa caaataacca atcttattta aatattcaat gttttcaatt ctactttctt
    36781 taattctatt tgtatctatc ttaatccttg actttatgga gccaatagaa gttatatata
    36841 ataaaaccat taaacaaaag ttagtaccaa ttaatttaaa tacattaaga aatgatttat
    36901 ctataaaaac atcaggagac ccatttatgt tccaatgagt ggcaatggag tctggcaatt
    36961 gattataatt aaatactata aaaatactca ttccaaaagt aaatagtatt ggtattaaat
    37021 agattatttt aaatttcttt attattttat tttttttatt tataaaatcc atatctatta
    37081 ttaattttga atctacatct atatgaccta atttagaata aagttctgat ttaagattct
    37141 tagctttttt atgtgtatga atatatagta tactttcata taataaaaaa actatgatac
    37201 taataaaata ggaaagttcc aatttgttaa aagtaaaaac cagaataaaa actaatataa
    37261 ggtctataat aaaacctaaa gacaacaggt ttttaaattt tttatctagc tttataaagt
    37321 gattataatt tttatactct tggtctatag aaaccccata aatgtgtttt ttacctacaa
    37381 aatagggcat aaaataaaat gtagcataca tcaaaattag aatcggaaat attgtaaata
    37441 ggcattcaat cttactcata atatttcacc tcataattgt caaataaact tgaacttaac
    37501 gataaaaatt cctctttact aatacctgat aaataagatt ttgccactaa tagttccaag
    37561 tcaagcttat ttttttgacg agttgtgttg tctattttca ttggtaattg agccacaata
    37621 gcaccttttc ttctatcaat atttaagaat ccctcttctt ttaattcgtt gtaggatttg
    37681 ttaactgtat gtaaatttac accaatattt tcagccatac ttcttacaga tggaagtgat
    37741 tcatttattt tcaattctcc tgaagctata gctttagtta tttcttcttt aatttgtaca
    37801 taaatagatt tatcgctatt aaaatctaaa tttaaaacca taaaaaacct ccattatgct
    37861 ttataaatga aaacgattgt tatatacata gtataacata aaaaataata acaaacacaa
    37921 aatttaaatt tatattttgt aaaaattgta atttaaaaaa taacataatt tttattaaaa
    37981 taatacagat actatttata gatagaaata aaaattagaa aggagaaaaa atatgttaac
    38041 atatttaatg aaaagacaaa tgcataaaaa agatgatgga atgagtaaac caatgatgct
    38101 tacaggagct gtacttacag gtgtaggagc atatgctgta tacaaaatga taaaaaatcg
    38161 taaatctaat tctcaaatgg tcaatacaaa ttattatgga aatagcgatt atgatgatta
    38221 taaatatgac gaatttgatt atgactgtga ctgtagagat acaaaacagg attatgaata
    38281 tgaagaatta aaaaaaaaag taaaagaatt taattcaaga agaataaatt gtgaaaattg
    38341 tccacatgtt tctcaagaag aaatgatgca atatgtaaat agtgttaaag atgtaaagga
    38401 tgatgttgat ttacatgaag atgctaaaaa agataatatt tacaaagaag atgaatacaa
    38461 aaaatatgaa gaagaataag taatattctg tataatcaaa caaatagtaa tattaaacta
    38521 tttaatatct agtttctaat atgtaagttg taacttagct tgaaagaatc ggtatcattc
    38581 tttagagagt taagtaacaa cttacatttt gtttttataa attcgaatgg ctctttgtga
    38641 ctattttgta attttagata tattttagta tcaagggtaa ttgtgtataa taaaacttgt
    38701 atatgcagat agtttaaaat taaaatgaaa agaaaggaaa tagttatggt aaagttgtta
    38761 atagttgaag atgatagtac tatctctttt ggaataaagt atgctttaga acaagaagga
    38821 tttagtatag atatatcaaa agatttatcc agtggaaaag aaatgatttc ttctaatgaa
    38881 tatagcttga tattgttgga tgttacatta ccagatggaa ctggttacga gctttgtcaa
    38941 tatataagag gattttctca gattcctata atattcctga ctgcttgtga tgaagaagta
    39001 aatattgtaa tgggtcttga tataggcgga gacgattata taacaaagcc ctttagaatt
    39061 agagaattaa tatctagaat aaaagctgtt ttaagaagaa aagccaatac tgtagaagaa
    39121 agtaagaaaa tacttaagtt tggagattta agtatatata cattggaagc tagagtatat
    39181 aaaaacgata aagaagtatt tctgacatca gttgaatata aacttctttt aattcttata
    39241 cagaataaaa atactgtgtt aagtagaact caaatattgg aaaaactttg ggatgtaact
    39301 tatgattttg taaatgacaa tactctaaca gtttatataa aaaggcttag agaaaaaata
    39361 ggtgatgatt tatgtgaacc aatctacata gaaactgtaa ggggtcttgg ttataaatgg
    39421 ataggaagtg aaaatagtgt ttctatataa tccggaagtg aagaagtttt taagtaagta
    39481 tgttactttg atatttgtta ttattatcat atctattgga tttagtgtaa tcaatgtatc
    39541 tttaactaaa gatatgattg taagaaataa tcaggctata ataggaactc tatcaagtaa
    39601 gtatccaaac ttagaaagtg agatagtaga tataataact caaggaaagt ctatggaaaa
    39661 tacagattat ggtaagaaaa tattaagtaa gtataattat gataaatcta ttaggataaa
    39721 ctctgagcct attatttcta aattagtttt agatactatc aaaataaata taatattagt
    39781 atgtataata tttattttga tatttgtgtt ggttgttaga tattttaagt caatttacaa
    39841 tgatttatca gatatgacta aatatgttta ctatagttca gagggcaagt catttgatat
    39901 gaaaaataag aatcaagaag ggcagatagg tcttttaaaa actgaactat taaagatgac
    39961 aacaattctt aatgaaaagg ttgaactgtt aaaaacagaa aagatatttt taaacaatac
    40021 aatttccgat atatcacatc aattaaaaac tccaatgact tctttaataa tgttgaatga
    40081 tttattatat aatgatatac catatgaagt aaaaatcgat tttttgaata agataaaaaa
    40141 tcaattaaat agaatggatt ggttgattaa aagcatgctt aaattatcaa aggtagaagc
    40201 aaaagtgata aattttaaaa aggataaggt gaaatttagt gaactcatac atagagcaat
    40261 gcaatctatg aaaataccta tggagattaa aaatcaaaaa ctgactatag agggaagcga
    40321 taatatatct tatattggtg atattgattg gtctgtggaa gcattagtga atataatcaa
    40381 aaactgtgta gaacatactc ctgagtttgg aaatataact ataacctata aagaaaaccc
    40441 attattttct gaactaataa taaaagatga tggtgaaggt atacataaaa aagatatacc
    40501 acatgtattt aaacgattct atagaggaag aagtagttca aaagaagata gtgtaggaat
    40561 aggtcttgca atgtcaaaat ctataataga aagccaaaat ggcgatatat atgtaaacag
    40621 cgaaaaaggt aagggtacag aatttcatat aatatttcat aaaatgtatg atagtgacta
    40681 atctgtaata tttaattcac tttatagtaa tagccaaagc ctaatatatg aagtatagaa
    40741 tataaatatt ggaggtagtt atggaagttt taagagtaga aaatctaact aaaagttatg
    40801 gtaaaaatga aacaaaagtt gatgctataa aaaatgtaag tttatcagtt gaaaaaggaa
    40861 catttatagc aataacaggt ccaagtggaa gtggtaaaag taccttatta catttactgg
    40921 gaggagttga tagaccaact agtggtaagg tttatataaa tgatgttgat atatataatt
    40981 taaaaactaa ggacttggca atatttagaa gaagaaatat aggtcttata tatcaatttt
    41041 acaacttaat tccagtctta aatgttaagg aaaatatatt gcttccagca gagcttgaca
    41101 atagagatat tgatagagaa tattttgatg atttaatgaa aacattaggt ctaaatgata
    41161 gggaaaagca ccttccaaac caattatcag gaggtcagca acagagaacc tctatagggc
    41221 gtgcattgat taatagacct tctataatat tagcagatga gccaacaggt aatttagata
    41281 gtaaaaattc aaaagaaata ctagaattgt taaaattatc agtaaagaaa tacaatcaga
    41341 cactaataat gataactcat gacaaaaata tggcacttca agcagataga attataagca
    41401 tagaagatgg aatcataaaa agtgatgagg tgatgtagat gaatttgtat acatcactaa
    41461 ctattagata cctaaaacaa aataaaagaa gaaccattgt aactataatc gggataatac
    41521 tttcgacagc tttaatttgt ggtataggaa acatatttga aagttttatg gattatcaag
    41581 tgagagaaac tataaagaat gatggaagtt tccatgttac attttatgat gtaaatagaa
    41641 agaatgtgga gtatgtaacg aaatcagctg aagtagaaaa atatgcattt accaaacagc
    41701 ttggatattc taaattagaa aatagtgaaa atggtatagt aagtataaag caatatgata
    41761 aaaatgcaat aaacggatat aaaatttcta taaaagaagg tagatttcca gctaaggaag
    41821 gagaaattgt tctaagtgaa aatattatta atcttataga tgataactta aaaatagggg
    41881 ataagataac tttaaaagta ggagatatgt ttgattcaag taagaagaag attgatagta
    41941 tggtatttca tgagggggat tatatagcaa gtgaaaagga tagaactttt gaagttgttg
    42001 gtataattaa aaaacctgga tttgaacgtt ataatggaat tgcaactgct ataacttatt
    42061 ttaatcctat ggataattac aatgatacaa ttaatgtatc cgtagaagta agaaatccta
    42121 aagaggtgta tgaagtaagt aataaaataa gcaaaaatat atattcaaat aaagataaag
    42181 aagcagtttc tgatatgata aaatacaatg aacatttatt gaggttacaa ggtgctagta
    42241 agtatgcaga tataaatagc tctataaaat ctatcattat agcagtaact attttagtaa
    42301 tcatatgtac aattgctaca gtgtataatt cctttagtat ttctataact gaacgaaaaa
    42361 aacagtttgg gatattaaat tccataggtg ctacatctag tcaaattaaa agattagttt
    42421 ttatagaagg tattataatt agtttaattg gtataccaat aggactaata tctggaacag
    42481 tagccataga cttattattt aaaattataa ataagtattt tactgaatcg gttgttactc
    42541 agatgagttt acggatagtg tataatccaa taataattat tgttagtata ataatagttt
    42601 tgtttacaat ctttatatca attttattac ctgcaatatc agcttctaat atttcgccac
    42661 ttaatgtgat taaaaatact ggagagtata aagtgagaaa aatcaaaagc tcaagactta
    42721 ttaaaatgat ttttaaaact gaaggagtac ttgcatataa aaatattagg agaaatagaa
    42781 aaaaatttat agtaactctt ttttctttaa tgataagtgt aataatattt atatctttta
    42841 gtggatttac attactttta ctaagaagtg aagaaattag aaattctcaa agaaaatatg
    42901 atttatattt aactgcaaag ggaacagcta ggtctataga tgatactgta agcgaactag
    42961 aaggtattga tgggataaaa aactttgaat tggcaacagg acaatatgtt tctataagag
    43021 taagtgaaaa taaaataaat aaatccaagg aagatttaat tgggaaatat tatcaaaaat
    43081 ataaggttgg agatagttat gaatatgatt tcagtaataa tgatttaatt tttccaggag
    43141 attttgcaat aagaaataaa ataaataact taatacaggg ttcttttaat aaggagagag
    43201 caattcaaga gaatggtgtt atattagtta gaaaaagctc atttgaatca aagggtaaga
    43261 aaggtgtagt agaacttacc aactacaaag taggagatac agtaacttgt gaatatcttg
    43321 atgaaaatgc ctcaagtaaa aaaataaagg ttaagattct tgctataact gatgaagaac
    43381 gtttaggtat gggttatcaa aatatgggat tacaatttat aacttatgat gaagttgcta
    43441 aaaatttaaa cctaaagtta agtaaaagtc ttatatttat tgattcagga ggaagcatta
    43501 agactaagaa ggaaatagaa gctttggcta ataaaaataa ttttaacttc tatgatgaaa
    43561 gtgcaattac tgaaagcgaa aaacaaaatc taaaagttat taaaatattt gtatatggct
    43621 ttatagcagt aatatcttta gtaagtgtta caaatattct aaatacagta agcacaagta
    43681 taaatctaag aaaaggagaa cttgcagtaa tacaatctat aggggttact cctaaaggtt
    43741 ttagaaaaat gatatattta gaaagtttta tatatggtat actgtcattg ttgtttggga
    43801 taccgattag tattggtatg actctaatta tgaataaact tatttcaggt gtaattgagt
    43861 tttctccgat tataccatgg acagcaatag ttatatgtat agtaagtgtt tttataataa
    43921 cttttatagc aggttatata ccaataagta aattgaataa agaaaatata atagataata
    43981 taagaagaga aagtatatag atataaagat aatttttaac tatataaaat attattaaaa
    44041 tcatttaaat gatataaaat attattatat cacttaaatg attttttatt tatataagaa
    44101 atctaataat aaattactag aggtatttaa ctatttagaa agaattggta ttatataaag
    44161 taagaggata tataataaga aagaatattt gattttattg gaaaacaaag aaaaagaagg
    44221 tgattactat ttctcatata actgcgaaga atatgtataa aagtttagaa gaaagaataa
    44281 acaagtttcc acaaggtgct ccaccctcag atacattata caagatacta aatgtattat
    44341 atacagaaca agaggcgaag ttagtggctc agcttccaat aaagcctttt agagtaaaaa
    44401 cagcagctaa aatttggagt gtaagtgaaa gtgaagcata tagagtatta gataaacttg
    44461 ctagcaaggc tctgatacta gatatagaag ataataaagg gaagaaatat ataatgcctc
    44521 ctccaatggc tggttttttt gagtttgcca tgatgagaac gagacacgat atagaccaaa
    44581 aacttttagc agaactttac tatcaatata tgaatgtaga agaagatttt atcaaagatt
    44641 tattttattc aacagaaact aagcttggaa gagtatatgt tcaagaggaa gttttaacta
    44701 atgataatga ggttagtatt ttagattatg aaagagctac tcacataatt gacgaatcaa
    44761 ctcatatagg tataagtatg tgttactgta gacatagaat gcaacatgtt ggaaaagctt
    44821 gtgatgctcc tatggatata tgtatgacgt ttgacaatgt agcaaattct ttgataaaca
    44881 ataaatttgc aagacgtgtg gataaagtag aatgtaaaga actacttcat caagcatatg
    44941 agcataactt agttcaatgt ggagaaaatg ttagaaaagg ggttacgttt atatgtaatt
    45001 gctgtggatg ttgctgtgaa gcaatggtag cagctaaaag atttggaaat cttcatccag
    45061 tacagacaac aagttttata ccaaatataa accacgaaag ttgtgtaaaa tgtggtaaat
    45121 gtatagctgc atgtccaata gatgcaataa gcaaggttaa ggaagatggt aaagaatata
    45181 taaaaattga tgaggataga tgtctaggtt gtggagtttg tgttagaaat tgccataaaa
    45241 atagcattat gttattaaag agagatgaaa aaataataac tccagcaaat tcagtacata
    45301 gagcagttct catggcaatt gaaaagggtc agttacaaaa tttaattttt gataataatg
    45361 ctttagctag tcatagagct atgggagcta tactatcagc tatattaaag cttgaaccag
    45421 ctaaaaagat tttagctagt aaacagttaa agtcagtata tttagataaa ttgttaagta
    45481 tgaatgataa atagaaacta acttaaaaaa gacaaggttt ttaggcttat ctacatctta
    45541 ataaacttat tatttaatat ctaaatttaa tttttacaca tataaaactt ataattgaaa
    45601 taaaaaaaga ctatattcaa ttaatattac ttgaatatag ccttttttag ttatgttaag
    45661 ctatttcttt tatttgttta aatgagtttt catttccatt tccaccaatt tgtgttatag
    45721 atttaaatct catagtttta aatagttctt tttggttata atctagtgag tttcctacta
    45781 gtattacagg agatttagtt tttccagcca aaactccaac agataatcca tctattaaat
    45841 catcttgttt attcattcca tttttagcaa catataagtt atctatctta gaatccttgt
    45901 aaaattcttt tattactttt gcattagttt catttctagt gctacctgat attctctgtg
    45961 gattttgaag tttgctttct atatttttag aaactgtata ttctccaccg attacataag
    46021 atttatcaat ttttttgttt ttaaataagt tatttatttc agttatatta ctattttcat
    46081 tagtaagtat tataggcatg tcattttggg ctgatacagc tccaatgctt actgcatcag
    46141 ctaatccttt ttcaccatta actactgaaa tttttgatat attactaata ttattcaatt
    46201 ctttagcaat gttcatagaa gtttgatatc tatcacttcc tgaaattcta gagacagaga
    46261 tattatttga ttttatagta tctagagaat tttcatttat agaagcctct ccaccaacta
    46321 catatacatt tttaactttt aatctcttta attcagccaa agttttttca tttatttgag
    46381 agcttccagt taataatata ggagcatttt tcttgtatgc aaatggtgtt gcagccaaag
    46441 catctgcaat tgctgagtcg tttattaaaa ctgcattttc agcattttcc caacctgctt
    46501 gacttatctt aatagaagtt tcatatctat cagttcctgt aagtgcactt gcatttactt
    46561 cgtcttgata tgtaacttca aatctagcat ttggacttcc taagaaaaca attacgcctc
    46621 cttttggcaa tctaactcta ttgttctttg taactaaaga atagtttaca ggaactcctt
    46681 tatcatcata aacggcaaaa gatgaatttt gaggaagatt aacttctatt tttttatttg
    46741 ctatatcatc accaatctta taccattttg cataaccatt agatgctagt tcgcaagtaa
    46801 aagatttttc tgctggcaaa ttagttatag aatcttcact aacatatgtt tgtgtggcaa
    46861 aagataaata ctctgtacca ttttctttat aaagtttaat atcggataaa tcacgaccta
    46921 ttacaccagg tatttctata aaagcatttg aattattctc atctattatc ttagtattaa
    46981 ctatataacc tggagtttca tcagaaaggc caggagttgc cttcacagaa ccaaacatat
    47041 agctttgaga agtatatttt tcatctacta gatagtaacc tttaccattt ctttttttcc
    47101 atacttcttt tacactattt gatatattgt tatcatctac cttttgagct acatagtata
    47161 aacttgctgt ttgacctaat ccagggacat catcataaga gctcatattt agatatgtaa
    47221 tattattttt ttcttttaca aattttaaac aactattacc tttttcagat acaaatctat
    47281 cttgacctat gtatatgtat ttatcttcag gtccattttc tatataagga gaagataccg
    47341 ttaaagtacc attatcatta acatcaactt ttaccatatt tgaagaagca taaagcccac
    47401 tattttcttt taaatgactt ggcattttaa cttgttgtgg cttactaaat gttttatcag
    47461 gttttatttc tttaattttt cccttttctt ttaaggcaga caataagatt tcttgtccaa
    47521 ttatttcatc aaattggcta tttccaccag aagaaagaac tgcaactgcc atattttcat
    47581 ctggaagaac tataagatta ctgtggaata gtaaagaatc tccacctttt gtaagagctt
    47641 ttaaattgta ctgattaaat ggataagtat tgacacaatc ccatcctaaa ccatatccaa
    47701 gtatagaatc ttctccttca ggccatagac catttaaata ttctttgttt tccatagctt
    47761 ttactgaagc aggagaaaga ataccatttg agtttttcat aaatgtttgt gcaaatgtac
    47821 atagattttc tgcacttgaa tataaaccac ctgcccctat agcattaagg ttatcttgtg
    47881 gaactgcatc ctcccaataa ggtacatatg cttttgctag ttttgaacta tcaaaactat
    47941 tttctgtagt ttttgtattt tgtaagttaa gtggattatt tatgtatttg tcaagaaaat
    48001 tagtaaatga cataccagat actctttcta ctaaaatttc agctaaagta aatccatcat
    48061 tacaataaac agaaaaagct cctggttttg cttttaatct ttgtttttgt aattctttta
    48121 agaagttatc atgaccataa gaatcattgt ctcctaataa gagcgtattt ttaaagctgc
    48181 ttcccatcaa tcctgatgaa tgatttaata acattcttgg tgtgatttcc ttgtatctat
    48241 tatcagccat tttaaattca ggtatataat ttacaacagg agtatctaaa tttacttttc
    48301 catcatcaac caacttcatg acagctgttg tagtaaacat tttactgata gatgcgatac
    48361 tatacatatt atccttagtt aaatttttgt tatcttgttt gctgtaaact ccaccattac
    48421 cagaaatctc aattttacca ttatcaatca aggcatattg agcatttaca acaccatact
    48481 ttgatagcaa agtttggatt ttctctttag caagagcttt agttttcgtg taagattccg
    48541 agtttttact ataatcatgt aattctatat cagaactttg atatttttcg gaattatctt
    48601 ttgtattatc agcaaaagta atatttggag cagcagtaaa taacatactc aatactaatg
    48661 tactagataa taatttagag agctttcgct taaacatatt acattacctc tttccctttt
    48721 taataattta taattagcat aacattctta attattttaa tcaacagatt attatcaata
    48781 aaaaaagctt ttataagtat agctttttat ataactgaga aaaatataaa aataatattt
    48841 gttgctgtat aaagaataaa gggtataggt aatatataaa taaaaatgga ggaattttag
    48901 atatatgtac aagaatataa ataagaatca acttaaagaa atgatgaaaa atgaaaagga
    48961 tattttatta ttggatgtaa gaactaaaga tgaatttagg gaacataaaa tagaaaatgc
    49021 tataaatata tcattacaag agttaatcaa taatatagat gaaatttacg agtataaaga
    49081 taagaaagta gtggtttatt gcagaagtgg tcatagaagt gttactgcat gtaatttgtt
    49141 agctgaagaa ggttttgaac atttatataa tttaaactca ggaataattg attacatgaa
    49201 ttaaataata taagttatgc attaaatact atatataatt ctgcttatta agtaggaata
    49261 tctttagata tttataagat agatttagga aagaacgaat ttttatactt tttttgaggc
    49321 atattctgta gtaaatatta gtttttaagt tgaaaaaagg tagtagctaa aaagctacta
    49381 ccttttaata tgaacttaaa gtattgttaa aaaatatatt taaatacaga attaattttt
    49441 taatgaccag ttaagttact atcgccaaat ttatcattaa atggttttat aattctattt
    49501 ataggtcctt taagaaggac atttaaacaa atagacagaa tcataaatag caatagaact
    49561 agtatatctt tagttagatt tggagcatat ataccaccaa ctgcttccct tgtagcacct
    49621 attgcataag taaatggcat gatagggttt attctttgga agaatgtagg tgtaacttgt
    49681 atagggaatg taccaccaga agaaccaatc tgaacgacta atagtactat tgcaattgct
    49741 tttcctacat ttccaaatac agaaactaaa gaatacacta taaagttaaa taccatacta
    49801 gtaaacataa gcaaaattat caataaaatt ggatgttttg ctgttactcc taataataat
    49861 atatctccag ttccgattat aaaaccttga acaagagcta tacttaaaaa agtaagacct
    49921 cttccaaagt aaatttcata aggtttatag tttccatgta cagatgtaga tagtaatgct
    49981 gaaataagta atataccaac ccatgtagaa aggacactat aaaatggtgt cattgcagaa
    50041 ccataatttt caattggata taatttttct gttttcactt caacaggttc ttttaagaaa
    50101 ttagattttg tcaatatatc actttcaagc aagctgacta attttttcat atcttcacca
    50161 ttactaattt tgtttaaagt ttcaatcaaa tcatccaaca tcccttttgc taaaggaagt
    50221 ctttctctta ttaatgatat actttcctgt gcatttcctg aaagttttag agatgtagta
    50281 agtatttctt caacctttgg aagttttgat tctgctttat ctaaaacagt aattatatca
    50341 tttgctactt ttatactgtt tgcaaatata ctatttatag gttttgatat ttttgagtca
    50401 aaattattta aaatatttaa attaattctt ccaataccat ttgatagact taaaacatta
    50461 ttcaaagcac ttacagatgg ttgttgtcca gatataactt tgtttttaat atcatttaat
    50521 gttgatatag atgaatctat tttattgcta gagtcttcaa gattatttat tacatcatcc
    50581 aatctattat ttgatgtaag ttgatttaat ttagttaaaa aatccaccaa agtatcgttt
    50641 aaagattgta aattagaaag tttttctgat aaattatcta tcaacttagg tacatcttca
    50701 ctgccactat taactgcatc aattaaattt aatgtaagag aagaagcaga agacgaaagg
    50761 tcaaccatta aatttaagtc agacttaata agaggagaaa gttcatctaa attatcattt
    50821 gtatcctcta agaatttctt taagtcactt gataacagtt ttgtatcatt caaagtcttt
    50881 ttaattgtag gcaaatcaga tttaatatct ttaactgtat cagataattt tgaagtagca
    50941 tcagaagcta aatcaacagt cttatttata tggtcaaatc tcttttgaag gtcaataagg
    51001 gaattttcaa cctttgttaa ctttggaaga ctgtgttcga ttcctgcacc aactccgttt
    51061 gatataccaa gaacgatttc actaactgtt tttactatag tctgattaac ctgtaattgt
    51121 attgtagaag cacctttatc tgtaatcttt ggtgcaactg catttatttt ttcattaaca
    51181 gtatagataa tttcgccttt tttaacatca tttgtaatta aagatgtcaa atctttagta
    51241 aaattttttg gaatcttaag tgatgcatag taagtaccct tcttaacacc ttcaagagca
    51301 gttttttcat ctacaaactg ccaacctaaa cttttgttat ccttaagttg ttcaattaat
    51361 tggtctccta cattaatctt ttgtcctgct atttcatttc ctttatcttc atttgttact
    51421 gctacaagca tattagcagt gcttccataa gggtcccaag atgcctttat attgaaccaa
    51481 gcatacagag atggtaaaaa agcaagacct aaaactatta caagtactgc ataattacca
    51541 cgtatatctt ttaggtcact tttaaaaatt tctaatatat tttttaaacc ctttgaaggt
    51601 tttaaattct tgatattatt ccagtttaaa atttctttta aactattagt ttttttcaaa
    51661 tgtatcacct cctaaaatat tttgataaag aaaaaagtta gatttataat caattttaaa
    51721 ttatattact ttttacacaa atagtaaagt taa
//
LOCUS       DBGJFK010000025        46612 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.025, whole genome shotgun sequence.
ACCESSION   DBGJFK010000025 DBGJFK010000000
VERSION     DBGJFK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46612
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.025"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..196
                     /locus_tag="ACOIAP_001663"
     CDS             <1..196
                     /locus_tag="ACOIAP_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HGZ2638551.1"
                     /translation="IVKVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRD
                     INASINILKEGLRLITIQNK"
     gene            320..487
                     /locus_tag="ACOIAP_001664"
                     /pseudo
     CDS             320..487
                     /locus_tag="ACOIAP_001664"
                     /inference="COORDINATES: protein motif:HMM:NF024197.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
     gene            696..1847
                     /locus_tag="ACOIAP_001665"
     CDS             696..1847
                     /locus_tag="ACOIAP_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="double-cubane-cluster-containing anaerobic
                     reductase"
                     /protein_id="HGZ2638552.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRAAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVKKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            1872..2627
                     /locus_tag="ACOIAP_001666"
     CDS             1872..2627
                     /locus_tag="ACOIAP_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008047 - enzyme activator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase"
                     /protein_id="HGZ2638553.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGVYFLNNNVRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAQGHEPVNISSM
                     CTVFAESEIVSLLAQNISAGEVAAGILKSIANKSTSMLARGEIIDEVAFTGGLAKSKE
                     LVKMIEEILDKKIFIAEDTQIIGALGAAVIGFR"
     gene            2819..5206
                     /locus_tag="ACOIAP_001667"
     CDS             2819..5206
                     /locus_tag="ACOIAP_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HGZ2638554.1"
                     /translation="MKRFTSKKVARFVALFLISILVMSTIPASADTSNTLNQIKKAEY
                     SETYKQYLNDVKNGRTEKYNGIIPNPYQLEGTQIKSKGRTAPTSYDPRKLGLMTSVKN
                     QENLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMDGALNYE
                     AMGYLTSCSGPKLEKDIPYNGKISKAQGATKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSAYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKSNFNSNI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGQKPSDDEKMYQHD
                     YASIVPLISNKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTTQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSKFYPCNFTIKAVTEKSSSESVPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGGSIVDALAATPFTSAINSPILLTQKEALNSKTKVEIQRLG
                     AKKVYLIGGENSISKETEQQLKSLNISTERISGSDRYKTSLLLAQKLNSIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNVFVVKNGIKSQNDLIDGLAVG
                     PLGAKTGSPVVLVGDKLADSQKEVLKNKTLEKVTQVGGGANQNAFKELVKLKSVK"
     gene            complement(5429..5662)
                     /locus_tag="ACOIAP_001668"
     CDS             complement(5429..5662)
                     /locus_tag="ACOIAP_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HGZ2638555.1"
                     /translation="MTTTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            5952..6542
                     /locus_tag="ACOIAP_001669"
     CDS             5952..6542
                     /locus_tag="ACOIAP_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2638556.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMELYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRLDKSITCEQLTDIFMKFYRMV
                     DSTSILNLMVNGEFEILVRKLPDAIIEEHFRHDDFEIGEIISCIPNAKNKDIERFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            6656..7501
                     /locus_tag="ACOIAP_001670"
     CDS             6656..7501
                     /locus_tag="ACOIAP_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638557.1"
                     /translation="MIKVDDLSFSYTDKNFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYKGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDKLLKSVGLENKANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVKYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            7498..8181
                     /locus_tag="ACOIAP_001671"
     CDS             7498..8181
                     /locus_tag="ACOIAP_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638558.1"
                     /translation="MRLKNLVLGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMLIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLVDTKSYANFYPFNICISLISGDKNFIVINILILISMIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            8178..8894
                     /locus_tag="ACOIAP_001672"
     CDS             8178..8894
                     /locus_tag="ACOIAP_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638559.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYLLMFDLLLAFITPFMFFFASTMVVLGEIDDSISRYLIVTPLGK
                     TGYLVSRFGIPGILAFIITMILLIFFSLTRISFLLNLSISLLVLLQSVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKVQYILFFLPTFWLSKAFKEDNYIYMFISI
                     IISLIWILLLFKKFSKKIVK"
     gene            8991..9254
                     /locus_tag="ACOIAP_001673"
     CDS             8991..9254
                     /locus_tag="ACOIAP_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638560.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            9226..9681
                     /gene="def"
                     /locus_tag="ACOIAP_001674"
     CDS             9226..9681
                     /gene="def"
                     /locus_tag="ACOIAP_001674"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGZ2638561.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            9742..10203
                     /locus_tag="ACOIAP_001675"
     CDS             9742..10203
                     /locus_tag="ACOIAP_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HGZ2638562.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHILVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTGILKWKNRNFANDISNEHSLDLENL
                     YDGWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWYGNIMF"
     gene            10253..11155
                     /locus_tag="ACOIAP_001676"
     CDS             10253..11155
                     /locus_tag="ACOIAP_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGZ2638563.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSIRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINLLFRHAKECNVHYVLP
                     GTLYLRGITRGIFFDFVKKEFPELFDKLSILYSTGSLNRGYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            11506..12336
                     /locus_tag="ACOIAP_001677"
     CDS             11506..12336
                     /locus_tag="ACOIAP_001677"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2638564.1"
                     /translation="MLNKLCMYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGA
                     SRNFNFIEDSVNWIVTVANPVKYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSIN
                     YAQNRNKETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSL
                     KPGGKLILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTL
                     VITEKDENVFYVWNHYFSKESFLFEIENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK
                     "
     gene            13385..14146
                     /locus_tag="ACOIAP_001678"
     CDS             13385..14146
                     /locus_tag="ACOIAP_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HGZ2638565.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQCINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWSGKRVFIIATMALFSGDGSGVLSRMLKKY
                     GAITVGGLHVRMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKYGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNVYTDKIKINAEECIVCGNCISLCPMKNLVIKNDMIISN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            14272..14580
                     /locus_tag="ACOIAP_001679"
                     /pseudo
     CDS             14272..14580
                     /locus_tag="ACOIAP_001679"
                     /inference="COORDINATES: protein motif:HMM:NF014609.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            14501..14977
                     /locus_tag="ACOIAP_001680"
     CDS             14501..14977
                     /locus_tag="ACOIAP_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HGZ2638566.1"
                     /translation="MESLKLHEMIFPEIMFIGIELSPQQTNLIGCVPIAVYSSRDLIL
                     LLNSEQEVINYKPNYTQLSKLTDWLGIIITAQGSNTDFVSRYFCPELDSGNPVTGSLH
                     CNLIPYWSEKVEKRKMVAAQLSNRGGIIQCKLLRDNTVKISGKVVLFIQVTIKIDI"
     gene            15263..15682
                     /locus_tag="ACOIAP_001681"
     CDS             15263..15682
                     /locus_tag="ACOIAP_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HGZ2638567.1"
                     /translation="MDKISGKLTVLFEEPFWIGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDKIGYKRMQRKVKKEQEKGSIGTKAQNALKLQY
                     EERKQDRKNLAKARKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(15783..16049)
                     /locus_tag="ACOIAP_001682"
     CDS             complement(15783..16049)
                     /locus_tag="ACOIAP_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGZ2638568.1"
                     /translation="MKKFILIYFIVINFIAFFSMYIDKERAIKHKWRIKEATLMYIAV
                     IGGSIGSMIGMYSFRHKTKHIKFTFGIPFIIFLQFLLVYFYILK"
     gene            16276..16977
                     /locus_tag="ACOIAP_001683"
     CDS             16276..16977
                     /locus_tag="ACOIAP_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HGZ2638569.1"
                     /translation="MKFVVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDIDFRNDDVYVRFSKKGDKFVPFGETDAELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            17059..17667
                     /locus_tag="ACOIAP_001684"
     CDS             17059..17667
                     /locus_tag="ACOIAP_001684"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGZ2638570.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSNE
                     QLKNIYLKNEEDSVDAVVLAGLHKSSKKLILIRQFRVPINDYIYELPAGLVDEGESID
                     VSVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDKFLEADE
                     EIEALLISQEEAKEILQSNHKIDTKAFLILQMFVSLGTKLFE"
     gene            17991..18455
                     /locus_tag="ACOIAP_001685"
     CDS             17991..18455
                     /locus_tag="ACOIAP_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HGZ2638571.1"
                     /translation="MKKLVIILISIINVVSLTACKKSNESKYNNLNNKESGQTTIEME
                     LDKNYDTSDSFVNARLFCVSNDIDVLETEISFQMDGDSGIVEIKDNKTDETLWSNTWH
                     GRVDNDTFTISLANIQKEKEYAIWFTGIKINHAIVKVSFESNLVKEKEIPSK"
     gene            18843..19859
                     /gene="gap"
                     /locus_tag="ACOIAP_001686"
     CDS             18843..19859
                     /gene="gap"
                     /locus_tag="ACOIAP_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGZ2638572.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEEEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            20255..21424
                     /locus_tag="ACOIAP_001687"
     CDS             20255..21424
                     /locus_tag="ACOIAP_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638573.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGKEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLIV"
     gene            21805..26058
                     /locus_tag="ACOIAP_001688"
     CDS             21805..26058
                     /locus_tag="ACOIAP_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydratase activase-related protein"
                     /protein_id="HGZ2638574.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYERFGNINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGAKQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEYSIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINDIYDILPKDVKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEINNAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANIQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMLERESKNIDVKNIKVNRIQYAKNNHITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAMYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKTSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEVFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            26207..26701
                     /locus_tag="ACOIAP_001689"
     CDS             26207..26701
                     /locus_tag="ACOIAP_001689"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGZ2638575.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDDFIVSVYIGDEKFNNLKNEYIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKNIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            26817..27194
                     /locus_tag="ACOIAP_001690"
     CDS             26817..27194
                     /locus_tag="ACOIAP_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HGZ2638576.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTRAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            27401..27841
                     /locus_tag="ACOIAP_001691"
     CDS             27401..27841
                     /locus_tag="ACOIAP_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HGZ2638577.1"
                     /translation="MDNINLLINRLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMINNENSYIRARGLLLISANAQWDIDNKIEINIDSILSHIVDKKPFVSRMFIKSIPN
                     ITKYKKNLIRRIKMELSNADISIYNNNMKPLVEKDINDTLSNLS"
     gene            28473..29780
                     /locus_tag="ACOIAP_001692"
     CDS             28473..29780
                     /locus_tag="ACOIAP_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638578.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKAEIGCVEEIDSEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVITIDKRY
                     DYRKELKLELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYAILVEQSKVLTDEAFDCNLASRNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    29866..30132
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            30258..31061
                     /locus_tag="ACOIAP_001693"
     CDS             30258..31061
                     /locus_tag="ACOIAP_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2638579.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGNTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            31099..31710
                     /locus_tag="ACOIAP_001694"
     CDS             31099..31710
                     /locus_tag="ACOIAP_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGZ2638580.1"
                     /translation="MLQGLEIVIAMFCITLIISIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRIIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            31741..32412
                     /locus_tag="ACOIAP_001695"
     CDS             31741..32412
                     /locus_tag="ACOIAP_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638581.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            32707..33069
                     /locus_tag="ACOIAP_001696"
     CDS             32707..33069
                     /locus_tag="ACOIAP_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGZ2638582.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPNKEELKS
                     IYKTSGYDIKKFFNTSGVKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLFDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            33504..34205
                     /locus_tag="ACOIAP_001697"
     CDS             33504..34205
                     /locus_tag="ACOIAP_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HGZ2638583.1"
                     /translation="MSIEDLYDFECVPLNNEVDIDVLFEKMIEDGKEKEYTPVIVIDE
                     KVGLLRKNIDIIIKEYGSLENYREYCLTKYNEIDVNQFFDFRKREISELLKELVDLED
                     DFYDYKHFRPIMNIDIFHEYNKIYIAKVPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKDLIKDGKKFDELCIELVFYCEDIIIQGYETLNAL
                     KDVLKRSTILLFWWD"
     gene            34514..35332
                     /gene="larE"
                     /locus_tag="ACOIAP_001698"
     CDS             34514..35332
                     /gene="larE"
                     /locus_tag="ACOIAP_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HGZ2638584.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVVAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGIDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSGLKKEE
                     IRSLSKILGLKTFNKPSFACLASRIPYGVEITDENLRIIEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            35387..36535
                     /locus_tag="ACOIAP_001699"
     CDS             35387..36535
                     /locus_tag="ACOIAP_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGZ2638585.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            36671..38059
                     /locus_tag="ACOIAP_001700"
     CDS             36671..38059
                     /locus_tag="ACOIAP_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638586.1"
                     /translation="MKVLKLITVVAMMMLFVTGCNIKTESPEQLAKIPNYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGS
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGNTGNNRNTYSSKASANIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTSTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            38088..38786
                     /gene="walR"
                     /locus_tag="ACOIAP_001701"
     CDS             38088..38786
                     /gene="walR"
                     /locus_tag="ACOIAP_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism DNA-binding response
                     regulator WalR"
                     /protein_id="HGZ2638587.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     ENDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALIRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            38789..40222
                     /gene="walK"
                     /locus_tag="ACOIAP_001702"
     CDS             38789..40222
                     /gene="walK"
                     /locus_tag="ACOIAP_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HGZ2638588.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVAFQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            40244..40981
                     /gene="truA"
                     /locus_tag="ACOIAP_001703"
     CDS             40244..40981
                     /gene="truA"
                     /locus_tag="ACOIAP_001703"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGZ2638589.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKAVEEVDERFHS
                     RYNVKSKTYMYRIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNIIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESRDRCQSSDTAPAKGLCLWKVRY"
     misc_binding    41092..41299
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            41552..42751
                     /locus_tag="ACOIAP_001704"
     CDS             41552..42751
                     /locus_tag="ACOIAP_001704"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HGZ2638590.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEIYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYETHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            43001..44047
                     /locus_tag="ACOIAP_001705"
     CDS             43001..44047
                     /locus_tag="ACOIAP_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtrH N-terminal domain-containing protein"
                     /protein_id="HGZ2638591.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNNFFFLLSGF
                     GSFCYMKTNKSELKRMVALGDGRTKKMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DSGHPVVLGALDMYYLPYYKKLYHIEHLPFHYVLMVGYDDEKVYLYDCGRTELLNLSY
                     DKLRESMNCSYPGLSKENTICTIRMNTSKNKYKIAKEVIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELSQWKTELEKDDYDKILTNMIMFFGTVPTIPNAIKGIKEPDTIQFKGGFDK
                     MSKMLKSIGEEYKNDSFIQVAEIFDKTSLIIEKISNIIVDYLTQKYDDTDQLPLLFSE
                     VLKDMKTGYLILNV"
     gene            44153..45316
                     /locus_tag="ACOIAP_001706"
     CDS             44153..45316
                     /locus_tag="ACOIAP_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2638592.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDDS
                     IKTLQQILFFKEIDIPLREVKEIMSSPYFDKLEALKNQRKLLILKRKRLDELIELINQ
                     TLRGEGNINFKEFDMSEYFDVLEEFKREHKSKIIKIYGSVEKYNEYIERVKFNEDKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEQHPKLKELYRKLAEDL
                     SKNPSSTELQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSKEIQSIVEEIDNEMKRSND
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGNGASKFIGEAFKIYFDNNNC"
     gene            complement(45405..45785)
                     /locus_tag="ACOIAP_001707"
     CDS             complement(45405..45785)
                     /locus_tag="ACOIAP_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HGZ2638593.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKNNISVLEKSIE
                     NENWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EIESIKTYLGNIIESVKFDVNYIF"
     gene            complement(45788..46447)
                     /locus_tag="ACOIAP_001708"
     CDS             complement(45788..46447)
                     /locus_tag="ACOIAP_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGZ2638594.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERVSIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
BASE COUNT        18787 a         4562 c         8049 g        15214 t
ORIGIN      
        1 aattgtaaaa gtaggtaaat tctttgcaag ttcacaaata tgcaataaat gtgggtataa
       61 aaacgaggaa gttaagaact taaatataag agaatggatt tgtcctagtt gtaatgaaac
      121 tcacgataga gatataaatg caagtataaa tatattaaaa gaaggattaa gactaataac
      181 aattcaaaat aaataactta tgtaagaacc gtaggaacta tggggatagc ctgtggagaa
      241 ttagtaagac atattttagt atgcaaaatt ctatgaagca ggaaccctgt gactttagtc
      301 atgggaggtt cagtggagaa catttcaaca agagtataga gattatttag atttagctaa
      361 gtttttacaa ctaatgcctg gaataggagc atttgtagga ttttatgtga atggaaaatt
      421 aattgataaa ttatgtgaaa ctgctgtgtc tgcttataga ttgaggattc gagagcttaa
      481 gttataaaag ttataagaga agttataaca taaaaaatta gttatacaat atatctatat
      541 acatttaatt ttgcattgat aaaaacaatt atggataaaa ggtaaagcat gatagaatct
      601 aatgtagagg tttgtatttt aatggaaaaa tttagttttt aatgtttaag atacaaattg
      661 gattatgaag agaagtgatt gggaggaata ttttcatgac aaatttgcca aaacaatttg
      721 atagctttaa tgaagctaga caaaaaggat ttataaatgc aaaggaactt aaggaaagtg
      781 ggaaaaagat ggttggagtt ttctgtacat ttactccagt tgaaattcca atggcagctg
      841 gagcaactgt agtaggtgta tgcggtgtta gtgaagagcc aatacctgat gcagaaagag
      901 tgcttccaag aaatctttgt cctttaatta aatcaagcta tgggcatgca ataacagata
      961 cctgtccata tttctatttt tctgatttgt tgataggaga aaccacttgt gatggtaaga
     1021 aaaaaatgta tgaagaactt gcaaaagtta agccaacata tgtaatgcat ttgccaaata
     1081 cctcaaaagg agaatttgcc tataaacttt ggaaagatga aatgataaga ttaaaagaag
     1141 aggttgagaa atctttaggt gtaactataa ctgaagaaga tataagagct gctataaaag
     1201 ataaaaatga agaaagagaa cttttaaaag aattttatgc acttggtaaa ttacaaccat
     1261 ctgcacttac aggtcttgag ttacataatg ttttatatca agcaggtttt aaatttgacc
     1321 gtgcagaact taaacattct ttaagaaaag ttatagatga tatgaaagaa agatatgaaa
     1381 aaggagaatg tcctgttaaa aaagataaac caagaatatt gataacaggt tctcctattg
     1441 gtggaataag tgaaaaaata gttaaaactt tagaagatgc aggggcatca gtcgttgcat
     1501 atgaactttg tggagctatt agatcaaatg atttattggt tgatgaagaa atagaagatg
     1561 tgtatgatgc tttaacacaa aaatatataa atataggttg ttcttgtatg atgaataatg
     1621 ataatcgtat tgagttatta gatagaataa tagatgaata taatgtagat gctgtaatag
     1681 atgtagtttt acaagcatgt catacattta atatagaaag ttatagaata agagagtttg
     1741 ttacaaaaga aaaaaacaag ccatttatgt ctcttgaaac tgattattca aaatcagata
     1801 ctgaacaatt gagaactaga tttgaagcat ttgtagagat gttgtagaaa tacataaaaa
     1861 taggaggaat tatgtttagt ataggagtgg actcagggtc agtggcaaca aaaggtgtat
     1921 tgtttgatgg tgaaaaaatt attaagaaaa taattatacc aactggatgg agccctaaaa
     1981 gtacatctaa acaagtttat gagttgttaa gtagtgaaat tgataaaaaa gatataaaaa
     2041 aagtagtagg tacaggttat ggaagaggag taatggattt tgctgataag aaagtaacag
     2101 aaataacttg tcatactaga ggagtttact ttttaaacaa taacgtaaga actattttag
     2161 atgtaggtgg tcaagatagt aaagttataa atttagatag agatggaaat gtatttaatt
     2221 ttataatgaa tgataagtgt gctgcaggta ctgggcgatt tttagagatt acttctaacc
     2281 ttttaggaag tgatatagaa agtattgata cattggctca aggacatgag ccagttaata
     2341 tatctagtat gtgtacagtt tttgctgagt ctgaaattgt aagtcttcta gctcaaaata
     2401 tttctgctgg agaggtagca gcagggatac ttaaatctat tgcaaataaa tccacttcaa
     2461 tgctagcaag aggtgagata atagatgaag ttgcatttac aggagggctt gcaaaaagta
     2521 aggaattagt gaaaatgata gaagaaatac tggataaaaa aatttttatt gcagaagata
     2581 ctcaaataat aggagcttta ggagctgctg taatagggtt tagataaaaa tataaataaa
     2641 ataaaatgag aaactgagtt tatcctaaat aaattcagtt ttttatttta ttttatttat
     2701 ttataaagga aaactttggt ataattgatt taaatgtttg tatatttgta aatacttgat
     2761 atttagtcat atataacatt agaattttaa aaattagctc aaaaaagggg gagaaagcgt
     2821 gaaaagattt acttcaaaaa aagtagcaag gtttgttgca ctgtttttaa tatctatttt
     2881 agtaatgtca acaattcctg catcagctga cactagcaat acattgaatc agataaaaaa
     2941 agcagaatac agtgagactt ataaacaata tctaaatgat gttaaaaatg gacgtacaga
     3001 aaaatataat gggattatac caaatccata tcaattggaa ggtactcaaa ttaaaagtaa
     3061 aggaagaaca gctccaacat cttatgaccc tagaaaatta ggtcttatga catcagtaaa
     3121 aaatcaagag aatttaggaa tatgttggga ttttgctgca atggcaactt tagaaagctt
     3181 cttgaagtta aataattatg gagattacga tttatcagaa gaacatttaa gatggtgggc
     3241 ttcagatggt gaatatggat ggtctgtaaa tgatatggat ggtgctttaa attatgaagc
     3301 tatgggatat ttaacatctt gctcaggtcc taaattagaa aaagatatcc cgtataatgg
     3361 taaaatatct aaagcacaag gagcaacaaa accaactaat atgaatacag cacctactgt
     3421 ttttaatgta acagatgctg tgtgtgtaag taatgacatt aattctacaa aaaatgctat
     3481 attacagtat ggggcagtaa catctgccta ttatgaagat attaaatatc aaagtgatga
     3541 ccaaaattca tattattgtc caacaaaaag ttttaataca aatcatgcta tatcaattgt
     3601 aggctgggat gataactatt ctaaaagtaa ttttaattca aatattagac catcaaaaaa
     3661 tggtgcttgg ctaataaaaa atagctgggg agattataac tctgaaggtg gatatttctg
     3721 gatatcttat gaagacaaga cacttatgtc tgatatagat aatttttcaa tcaaaggtgg
     3781 tcaaaaacca agtgatgatg agaaaatgta tcaacatgac tatgcaagca ttgttccttt
     3841 aatctcaaat aaaataacag cagcaaatgt attcgatttt aatagaggtg atgagactct
     3901 aaaatctgta atgtttttaa ctgaaagtat aggagctaaa tatgaagtat attatgctcc
     3961 agtagtaaat ggtatacctc aagaaaataa tatgaaaaaa ttaaaagaag gtactacaca
     4021 atattcagga tatataacag ttccaattga ttcttttgat ataccagaag gaaaaggtgc
     4081 aattgtagtc agtatagagg ggaaaaatgg agaatcaact ataggctctg agtcaaacgt
     4141 gccaggatat gatacattta aagcaaaagc taatttaggt gagagttata ttatagataa
     4201 tactggaaag ttctttgata taaacagaga tagtaaattc tatccatgta attttactat
     4261 aaaagctgtt acagaaaagt cttctagtga gagtgtacca aatgagtctt taattggtag
     4321 tgatagatat gaaactgcta tcaaagttag tcaaaatggt ttcaattctt cagaaaatgt
     4381 agttttagta aatggaggtt caatagtaga tgcattggca gcaactcctt ttacatctgc
     4441 tataaattca ccaatattat tgacacaaaa agaagcttta aattcaaaaa ctaaagtcga
     4501 gatacagaga ttaggcgcta agaaagtata cctaataggt ggagaaaatt ctataagtaa
     4561 agaaaccgaa caacaattaa aaagcttaaa tatatcaaca gagagaatat caggaagtga
     4621 tagatacaag acaagtttat tgttagctca aaagttaaat agtataaaaa atgtatctca
     4681 aatagcagtt gtaaatggag tgaagggatt agctgatgca attagtgtag gtgcagcagc
     4741 agcagaaaat aacataccaa tcatacttgc aaatgaaaag agtgaattgc aaggagctga
     4801 tgaattttta aattcattaa atatagagaa atcttatatt attggaggaa cagcatccct
     4861 atcaaacaat ctagaaagta agttaaaaaa tccaactaga ttatctggta gtagtagaga
     4921 tgaaactaat tcaaagataa tagataattt ttataaaaaa gatactttaa aaaatgtatt
     4981 tgtagttaaa aatggaatca agagtcaaaa tgatttaata gatggattgg cagtgggtcc
     5041 tttaggagca aaaactgggt caccagtagt tttagttggt gataaattag ctgatagcca
     5101 aaaagaagtt cttaagaata agactttaga aaaagtaact caagttggtg gaggagcaaa
     5161 tcaaaatgca tttaaagagt tagtaaaatt aaagagtgtt aaataggata cttaggtatt
     5221 ggtatatatt aatatgtatt agtaaattat actgataaga gctgaaaata attactttaa
     5281 attattgata aataagataa tcaatggttg caaagttttg ttttcagctt taaatttatg
     5341 tagtataagt ttaaaaacat aaaaaagggt tactttatat agaaaatctt acattttata
     5401 tataaataac ccatatttaa ttaacttttt atagtgttct aatagatatt attgaactta
     5461 atggtaaata taatgtgtaa gtttcgttta aagttggatt agattcgtct atatatcttg
     5521 agcaaagtgt aattgataag ctgtctgctt ctataatttc accatataga ggacaactgc
     5581 tgaagtaaga atgtacttca acgtatttat ttaaattttc ttgaacataa tcataaaaac
     5641 ggttctttgt agtagtagtc ataaaatcaa ctcctttatt ttttattaaa gctgaaactt
     5701 ttaaaaagat aaatatgatt acttctatta gaaactaagt taaaaaataa gcaaatagat
     5761 atgaaaacta gaataatata ttatttatat cttaattata acattaaata ataaaaaatg
     5821 ctatataaaa ttcagaattt tcgaaagttt ttaagtctat ttttaaatat actagcaaaa
     5881 ctattgacat taaatagaaa aagtaatata ttgactatat aaaatatttt agtcaaactg
     5941 gaggacggaa gatgcctaaa tcatattctg acaaagaaag agagtatata ataaaaagac
     6001 ttaaagaaga agcaagattg tgtatggagc tatatggtat tagaaaaact actgttgatg
     6061 agcttgtaaa acgagtaaaa ataccaaaag gaacttttta tctattcttt caatcaaaag
     6121 agttgctttt ttttgaagta ttgagagata tacatgactc tatacagaaa gaaatcttat
     6181 atgagataaa tagactagat aaaagcatta catgtgaaca attgacagat atatttatga
     6241 aattctatag gatggttgat agtacttcaa tcttaaatct catggtaaat ggagaatttg
     6301 agatattagt gagaaagttg ccagatgcta taattgaaga acattttaga catgatgatt
     6361 ttgaaattgg agagattata tcttgcatac caaacgcaaa aaataaagat atagaaagat
     6421 ttagtggagc atttagagca gtctttctta ccatgttata taagcgtgag gttgggagta
     6481 attgttttga agatgcttta agattaatga taaatggatt agttatacaa cttatggaat
     6541 agaatttaaa ttttgtttgc taataacttt tattaaaaat tattaacaaa caaaaaaatt
     6601 attttttatt gactatatag ctaaaatggt caaaaggttg aaagggtgat atttaatgat
     6661 taaagttgat gatttatcat ttagttatac agataaaaat tttttacaaa atattaattt
     6721 tgaagtagga aaaggtgaaa tactaggttt tttaggtcca tcaggtgcag gaaaatctac
     6781 attacaaaag attctaattg gaatgataac taattataaa ggaagtgtca ttgtaaatgg
     6841 agtagagagt aaaaggcact caaataaatt ttatgaaaat ataggagttg attttgaatt
     6901 tcctagttta tatgaaaagt tgactgcaat agaaaattta aaatattttg ggtctctata
     6961 ttctaaaaaa ttactatcta ttgataagtt attaaaatca gtagggctag aaaataaagc
     7021 aaataaaagg gtatctgagt attcaaaagg tatgaaatct agattaaact ttataaaagc
     7081 tttattacat aatccagata ttttattttt agatgaacca acaagtggtc ttgacccatc
     7141 aaatagcaag gttatgaaag atataatttt atcagaaaaa tctaaaggta aaactattat
     7201 tttaacaact cataacatgt tagatgcaac agagctttgt gacagagtag cattcatagt
     7261 aaatggtaaa atatctgctt tagatacacc acataatctt attatgtcaa aaggagctat
     7321 taaagttaaa tatacttact ttgataatgg agaaaaaact tctgaatgtt ttctgaataa
     7381 tactgctaat gataaaaatt tgaatatgct tattgagaaa aataaacttt tatcaataca
     7441 tagtagtgaa ccaacattaa atgatatttt tattgagata acagggagga atttacaatg
     7501 aggctaaaaa atcttgtttt aggagatata aagtttcaat ttaaatatgg tttttatttt
     7561 ttatatcttt ttttaagtat tatatatatt tgtattatca atgtatttcc aacttttatg
     7621 agagaaaaaa tagctataat tatgatttat tctgacccag cagcaatggg attgtttttt
     7681 atgggagcta ttgtacttct tgagaaaagt caaagggttt taaattcctt agctgtatct
     7741 ccagtaaaag tatctgagta tattttatca aaggtaattt cattaggagt aatatctagt
     7801 attgtagcta tgcttattgc tattacatta aatttagata atattataat atcaactata
     7861 gggacttttt tttcttctat tatattttct ttgcttggat tgatacttgc aagtaaagca
     7921 tctagtttga atcagtttat tgttttaagt attcctattg agattatatg ctttattcca
     7981 ccaatactca atgtacttgt tgatacaaaa tcatatgcaa atttttatcc ttttaatata
     8041 tgtatttctc ttattagtgg agataaaaat tttatagtga ttaatatttt aattttaata
     8101 tcaatgataa taataattta ttttataact tattatttta tttgtagtag ttggaaaaag
     8161 gtaggtggag taaaactatg ataaagatta taaatgcgtt taaacaagag tttgaacaaa
     8221 ttaaaagaga cgctatgctt tttatagtat gtgtctctcc aatattatgt ggagtattta
     8281 taaaatttgg aataccctta atacagaata tatcacttaa caagttttat tatcaattaa
     8341 atttagaacc gtatttattg atgtttgatt tacttttagc ttttattaca ccttttatgt
     8401 tcttttttgc ttctacaatg gtcgtattgg gagaaattga tgatagtatt tcaaggtatt
     8461 taatagtaac tccgcttggc aaaactggtt atcttgtttc acgatttgga ataccaggta
     8521 tcttagcatt tattattact atgattctac ttatcttttt ttctctaact agaatttctt
     8581 ttttgttaaa cttatcaatt tctttattag ttttattaca aagcgttatt atatcaatat
     8641 tagtgatttc tttatcatca aataaactag aaggaatggt aattacgaaa ttctcaggtg
     8701 tttttatgat gggtatttta gcaccatttt ttattttaaa taaagtgcaa tatattctgt
     8761 tcttcttacc aactttttgg ctatcaaagg catttaagga agataattat atctatatgt
     8821 ttatttccat tattatatca ttaatatgga ttttactact atttaaaaag tttagtaaaa
     8881 aaatagttaa ataagacaat ttaatatata aatgtaaggt tgacttgaca gtaaaattga
     8941 aaaatgttac atttaaaatg taaggttaac attacatgaa tggagcaaat atgaaaaata
     9001 aaataaagat attaagagaa aaattaggat tgacacaaga acaactagga agattagttg
     9061 gaacatctag acaggctata aatgctatag aaactggtaa aaatgaacct tcaatatggt
     9121 tggcatatga tatttcaaga atttttaatg aaccaattga aagtgtattt ttatttgaag
     9181 aaagtgaaag aaaatcaaga gcacagataa gtaggggaga atattatggc tataagaaag
     9241 ataagaacat ttgatgatga aattttaaga aaaaagagta agtatgtaga aaacgtagat
     9301 aataagataa gagaaatatt aaatgacatg gcagagacca tgtataatac tccaaatgga
     9361 ggaggattag ctgcatgcca agtaggagta ttaaagcgac tagttgttat agatttagga
     9421 gaaggactta ttaagcttgt taatcctgaa attattaaac aagaagggga acaaattgtt
     9481 gttgaaggat gtttaagttt tcctgaagta tggggtaaat taaaaagacc aaaaaaagtt
     9541 acagtgcaag ctctaaacga atacggcgag aaaatagaaa ttaaaggttc aggttttatg
     9601 gcaaaatgtc tttgtcatga gatagaccat ttaaatggta tagtttttac agataaaatt
     9661 attgaacatg taaaattgta agatagataa gatagattgg ttattgaatt tataaaatat
     9721 tttatagtaa ggagttaaat tatgagatta tggcataaag atttaattga tgtattacct
     9781 aaaaatcaat tagtaagtca atggagagag ctacttgcta taaaaggttc tatagataaa
     9841 aaaggtactc caaaccatat attagtgaat aaagtgttga attatagtat agatgaattt
     9901 aaattttata caaaaattgt acatgatgaa atgttaaaaa gaaattataa acctaatgaa
     9961 cttaaatata caggtatatt aaaatggaaa aatagaaatt ttgcaaatga tatatctaat
    10021 gaacatagtt tagatttaga aaatttatat gatggttggc acaataaaat gtatttaaag
    10081 caatgcttat ataatttaga agaaaaagca acatgtggag gaatacccat aaatgaatgg
    10141 aatatattac tttgtaaata tagtaaagat tatgaattgt ggtatggaaa tatcatgttt
    10201 taattactat agattaacat tataatatta ttgtatataa agaggtgatt atttgtataa
    10261 taaaataaaa tatattccaa taaattgtga aatagcttgt aataaactaa aaaggagtat
    10321 gccatataaa tgggatttga atatttatcg tggatgtgag catgggtgta aatactgcta
    10381 tgctatttac tctcataagt atatcaactc caataattat tttgaagaaa tttatgtaaa
    10441 aacaaatata gtggaaaagc ttgagagaca acttaaaagc agtaaatgga agaaagaagt
    10501 aatcaatata ggaggagtta cagatagtta tcaaccaata gaagctgact ataaaattat
    10561 gccagaaata ttaaatttgc tgataaagta caagacacca gctattattt ctacaaaatc
    10621 agatttaatc ttaagagatt acgatttaat tgataagcta tctaggatta catatatcaa
    10681 tgtagcatct acaattacca cagtaaatga agatacacaa aggcttattg agccaaatgg
    10741 tgtggattca attagacgat ttaaaatgtt aaaagaattt agaaaaacta acgcatcagt
    10801 tggtctacat attatgccaa ttataccata tattacagat gattttgata atataaattt
    10861 gctatttaga catgcaaaag aatgtaatgt acattatgtt ttacctggga ctttatactt
    10921 aaggggtata actagaggta ttttttttga ctttgttaaa aaagagtttc ctgaattatt
    10981 tgataaatta tcaatactat atagcacagg ttcacttaat agggggtata aaaatcaatt
    11041 gtataaaatg gttaatgaac ttagatataa atattctcta tcaagcagtt actctaaaat
    11101 aatgaaagaa aagttaaaaa actcaggaga tgtacagata tctttttttg attagtttta
    11161 tataaaaaaa ttttttcact atgatgatta aaatttatta aaattaaaat ttattgacaa
    11221 gtattaaatt taaatataca attaattcat aaaataaaaa tatgaaagga tgatgttgtt
    11281 cagtgatact tgatattata aaatcattga tataagtatt gctggaaaag agtgaataaa
    11341 atcaaattta ataagcaaac aaagtaaagc tatagtttta ttgttgtgct taaaaatatt
    11401 tgattctatt ttactcttat ttaaactcat ctttttgaag ttaaatcaca gagtaaactc
    11461 tgtgattttt ttattttaaa aataaatttt aaggagtggt atgttttgtt aaacaaatta
    11521 tgtatgtatt tagaaagacc agagctttat aaacaaagtg aaattaattt ttgggatgat
    11581 gagtatattt caaagcaatt attaaaagca cacttagaca ctaattttga aggagcaagt
    11641 agaaatttta actttatcga ggattctgta aattggatag ttacagttgc aaatccagtt
    11701 aagtatccta aattacttga tttaggttgt ggcccaggtt tatatgcaga gaaatttgca
    11761 caaaaaggtt ataaggtaac tggaattgat ttctcaaaac gttctattaa ctatgcacaa
    11821 aatagaaata aggagactaa tttaaacata aattacttgt ttcaaagtta tttaaatatg
    11881 aattataatg aggaatttga tttggctact ttaatttatt gtgattatgg agctttgtca
    11941 actgaaaata gaaggttgtt aatggaaaaa atttatgata gtttaaaacc tggaggaaaa
    12001 ttaatattag atgtatttac aataaataaa tacaataatt ttgaggaaat taaatattgg
    12061 gaaataaatg aagatggagg attttggagt aatgaaaaat atatgtgtct acaagataat
    12121 tgtaaataca atgattataa tacattagaa caaactcttg taataacaga aaaagatgaa
    12181 aatgtgtttt atgtttggaa tcactatttt tcaaaagaaa gtttcttatt cgaaattgaa
    12241 aatattggat ttaagtctgt tgagtttttt agtaatgtta aaggtgaagc atattctgac
    12301 gatagtatga ctatgggatt agttttacaa aaataataat ttttttaaaa tgaataaata
    12361 aaaacttgaa acctctaata ataaaataaa ataagaaaag cttacatatt gaaaaatgga
    12421 aacttttatg ttatttttaa tacattacaa atttgcttat ataaaaatca acacttaaat
    12481 tattattttt atatgaaatt tatctatagt atatttttat aaacaagtaa tgctattaaa
    12541 attaagtata tagtcaaaag tgtatagcaa aaaggctgtt atattaatgt tagaggttca
    12601 gggaaaatat ataaagcaaa gatatttaca gataatgcaa atggtacaac tataagttag
    12661 ataatagaat tatgtaatca agaatttaca acaaagtcta agataaggat aataccaaat
    12721 tgccatacag gtgctagatg tgtaaatgaa ttaaattaat actattgata aagtacaaca
    12781 agcacataaa ctaattgatg agattattaa aactataaga gatatagttg acataattaa
    12841 aatattgtaa tctatttata attttattat aaatcaataa tgattaagat tgaaataata
    12901 ttaaggcatc aatgttataa gtttacaata taaggagtac tatatagtat tccttactta
    12961 cacatattag gcaataggaa gttttttcat agttaagttt tcaaatattt tttagggaac
    13021 tttgtaattg agaattaagg gtatagtatg tgatgaactt actaaattta taattaggtt
    13081 atataatgga ataatcatca atagttttac tttagggaaa atacatgctt aaggaagtat
    13141 agcttactaa tattattaaa atgtatattt aaaatgataa aaaaagaatt agacaagtag
    13201 ttagtaaatt gattatgcaa aattctatca agcaggaacc ctataacttt agtcatggaa
    13261 ggttcagtag gtaatctgtt gaattaagtt tatattattt aaataaacta cttaatttag
    13321 ataatacaaa aagtcagaat tttaagaata gagctatata atcttagcta ttaggagaat
    13381 tactatgata ggaatatatt ttagtggaac aggaaattca agatattgtg tagaaaaatt
    13441 tttacaagaa tatgatataa cagcaaattc ttattctatt gaagataatg aacttttaca
    13501 gtgtattaat aatcatgaga atattatttt tagttatcct gtacaatata gcaatgtacc
    13561 aaaaatattg aaagatttca taataaatca ttcaactttg tggagtggta aacgtgtttt
    13621 tattattgca actatggctc tatttagtgg ggatggctct ggtgtgttat ctagaatgtt
    13681 aaaaaaatat ggtgctataa ctgttggtgg attacatgtg aggatgccag atagtatagg
    13741 agatgaaaag gtattaaaac attctttaga gtataataga aagcttgtaa taaaagcaga
    13801 aaagaaagta actaaggctg ctaaaaaatt gaaatatgga tcaccaccaa aagaagggtt
    13861 aggttttttg agccatattg taggattatt tggacaacga ttgtatttta tcaataaaac
    13921 aaacgtgtat acggacaaga taaaaattaa tgctgaggaa tgtattgtat gtggtaactg
    13981 tattagttta tgtccaatga agaatctagt aattaaaaat gatatgatta tttcaaatgg
    14041 tcaatgtaca atgtgctatc gttgtgtaaa taattgtgct aaaaaagcaa ttacattgtt
    14101 aggtaaaaag gttgttgaac agagtaatat taaaaaatac atgtaagaac tttaaaattt
    14161 tactaaatat acattgatgt atactttatg ttagaaagag agctcaaata atggaatact
    14221 accataattg attcatttgc aactaaatta tttaaaggaa atactgctgg aatttgtgtt
    14281 cttggcagaa gaataccttt agagttaata cagaaaatag cagaagaaaa caatttacca
    14341 gaaacggcat ttgtagttaa agataaaagg aattatgaat tatgatggtt tactcctaaa
    14401 gtagagattg atttatgtgg tcatgcaatt ttagcagctg cttatgtaat atcaaatttt
    14461 attgatgtta atgtaaaaaa gatagatttc cttactcaaa gtggaaagct tgaaattaca
    14521 cgaaatgata tttccagaaa taatgtttat cggaatagag ttatcaccac aacaaactaa
    14581 tttgataggc tgtgtaccaa ttgctgttta ttcttcaaga gatttaattt tattgctaaa
    14641 cagtgaacaa gaagttataa attataaacc taattacaca cagctgagta aattgacaga
    14701 ctggttaggt ataataatca cagctcaagg aagtaataca gattttgtat caagatattt
    14761 ttgtccagaa ttagattcag gaaaccctgt tactggttca ttgcattgta atcttattcc
    14821 atactggtct gaaaaggtgg aaaaacgcaa aatggtagct gctcaacttt ctaatcgtgg
    14881 tggtataatt cagtgtaaat tattaaggga taatactgta aaaatttctg gtaaagtagt
    14941 cttgtttatt caggtaacaa taaagattga catttaaaga agtataataa ctaatttata
    15001 atttaattta ctatgaatta tgaaaaataa ttaattttct tagagttaat tataataaag
    15061 tagagtgaaa aaatttaatt tcatttaaag caatatgata gacgttgata ctaagattga
    15121 caagcatgat taaaaaagat agtatttaat ctataaagat aaaaacacag tctggttggt
    15181 agtccagacg cagcaatagc tgtaagtaac ctgcctcctt ggttgtccat tctttagaaa
    15241 gtaatttaag gaggaactag caatggacaa aattagtgga aaattaacag tcttatttga
    15301 agaaccattt tggataggca tatttgaaag acaagatggt aaaaaatatg aagcatgtag
    15361 ggtagttttt ggggcagagc ctaaagaggt agaagtatat gaatttatac ttgaaagatt
    15421 tttctcatta gattttggca gtattaagtt agaaaaaaat gtgactaaag acaaaattgg
    15481 atataaaaga atgcagagaa aagtaaaaaa ggaacaagaa aaaggatcta tagggactaa
    15541 ggctcaaaat gctcttaagc ttcaatatga agaaagaaaa caggatagaa aaaacctagc
    15601 taaagctaga aaagaagaag aaaaagaaag actttttaat ttgaaacaag aaaagagaaa
    15661 agctaaacat aaaggtcatt aattttaatt ggctttcttt ttaataattg cttgaaaagg
    15721 tgtatagaat caaaaacttt atacacctta atttattgaa aaaataaagc tttatatttc
    15781 aattacttta aaatataaaa atatactaat aaaaattgta aaaatattat aaatggtata
    15841 ccaaatgtaa atttaatatg tttagtctta tgtctgaaag aatacattcc aatcatagaa
    15901 cctatactgc ctccaattac tgctatatac ataagagtag cttcttttat tctccatttg
    15961 tgtttaattg ctctttcctt atctatgtac attgaaaaga aagcaataaa attaataact
    16021 ataaaatata ttaaaataaa ttttttcata gtcttgcctc cataaaaata tattatacat
    16081 tataaaataa gatatttgtt ttggaaagtt aattttgcaa ttagtacata taaaatactt
    16141 gataagaatt aatataatat taattggaaa atttaaaaaa attaaacaat tagcaaatag
    16201 ggggtatatt tataagagac aaagtgataa aatttactta gaaaataatg taaaataaca
    16261 ggaggataag acaaaatgaa attcgtagtg gaaaaagaag tctttgataa attagaaaat
    16321 gtatgctttg gtgtagtagt agcaaaaggc atagataaca ctaaagaaat cgaaagaata
    16381 agcaatcttt tagatataag tatagataga gtagaagatt acttcaaaga taaaaaagta
    16441 aaggaatcag aagaaattat accatataga gaggcattta gaagtctagg tatgaaccca
    16501 aataaattta tgagttcaat agaagcaatg acaacaagag ttgctaagaa taagaaactt
    16561 cctcatataa atcctatcgt agatttagga aactctattt ctttaaaata tttacttcca
    16621 atgggtgctc atgatataga ttttagaaat gatgatgtat atgttagatt ttctaaaaaa
    16681 ggggataaat ttgtaccatt tggagaaact gatgctgagt taatggaaga aggagaatta
    16741 atttattcag ttggagacat ggtaaaaact agaagatgga tatggagaca aggagaggaa
    16801 gggaaaatta ctaatagctc aaaaaatata ttttttccta tagatggttt tactgatgct
    16861 aatttagata aggtaatgag tgcaagagaa gaattagcaa aattgttaaa ggaaatattt
    16921 aattgtgaaa ttaaagtagg ttttgtagat aaagataatc ctgaaatgga aatataataa
    16981 gttgttgaat atttgttaag atattatatt tacttaatga tgttaaaaag gtattaaaaa
    17041 agaaaggtcg tagtaaattt gaaaaaaact ataataaaga atgtaaatcc aatgattgaa
    17101 aataagttta taggactttt tgaaatagag tataaaaaca aactagatga agataaggtt
    17161 tggatggtag catcaagaaa aagtaacgag caattaaaaa atatttattt gaagaatgaa
    17221 gaagatagtg tagatgcagt tgtattagct gggcttcata aaagtagtaa aaaattaatt
    17281 ttaataagac aatttagagt acctattaat gattatatat acgaattacc agcaggtctt
    17341 gttgatgaag gagagtctat agatgtttct gttgaaagag aacttagaga agaaacaggg
    17401 cttactcttt tagaaattaa aaaaaataaa agtattgata aagtgtatct atctcctgga
    17461 atgagtgatg aatctgttgc ctttgtttat tgtatatgtg atggggatat aacagataaa
    17521 tttttagaag cagatgaaga gattgaggct cttttaattt ctcaagaaga ggcaaaagag
    17581 attttacaaa gtaatcataa gatagacaca aaagcatttt tgattttgca aatgtttgtg
    17641 agcttaggaa ctaaattatt tgaatagata tatggaaaag aggttatata gagaagtaaa
    17701 ataataaagt ttattttact tttctaaatt ataatctctt tttttataca ataaagtata
    17761 attttgtgta tttttaaata agtgacttga ctcttaaatt ttcataatat gttataaacc
    17821 aattttagat actgcaataa ttaaaatcca aaaattattt aacatatttg caattaaaat
    17881 gagaaaaggt aaagactgaa tgattgaaaa atttgatgtg aaatagctga ttagtttaat
    17941 attatagttt gtagggttaa aaattagaaa ttgtaaagga gataaattct atgaaaaaat
    18001 tagttattat tttaattagt atcattaatg tggttagctt gacagcttgt aaaaaaagca
    18061 atgaaagtaa atataataat ctaaacaaca aagaatcagg acaaacaacc attgaaatgg
    18121 aattagataa aaattacgat acttcagact catttgttaa tgcacgtttg ttttgtgtgt
    18181 ctaatgatat agatgtttta gaaacagaaa tttcttttca aatggatgga gatagtggca
    18241 ttgtagaaat aaaagataat aaaacagatg aaactttatg gagtaataca tggcatggaa
    18301 gagttgataa tgatacattc acaatttctc ttgctaatat acaaaaggag aaagagtatg
    18361 ctatatggtt tactggaatt aaaataaatc atgcaattgt aaaggttagt tttgaaagca
    18421 atttggttaa ggagaaagaa ataccctcaa aataaattcc agtttgttta taacttaata
    18481 ttcagtacat aaaagcagtt aatatttatg attgactgct ttttcttatt taaaaaggat
    18541 gagctgtgca tttttaattg aaatagttca tacacattaa aaattggtga atatattact
    18601 ggagaaggat ggcaaaatat gtcccaaggg acattgagca aaataaatga cttcagcttc
    18661 tctgtgctaa aaagtatata ctaaataagg gttaaagtag ataaaaatga tacactaatt
    18721 gtcttttgat aataaaaaaa catgaaattt aattatttaa tcaagaaaaa gtattgaata
    18781 aatgatttat ttagtgtaca ataatcatgt aaaaacatag taatggaggg agacatttca
    18841 taatgaaaat taaggtagga atgaacggat ttggaagaat aggaagagct gtattaagaa
    18901 tagctcaaga agaattagga gataatatag aaattgtagc cataaatgca agagcaacaa
    18961 cagagtcttt ggcacatcta tttacatatg attcatgcta tggaactttt agaggtgaag
    19021 tagaagcaaa ggatgaagac acactagtag taaactctaa agaaataaaa atattaagat
    19081 ataatgaccc agaagaatta ccatggaaag aattgggagt tgatatagta atagaatcaa
    19141 caggattgtt tacacaaaga gaaaaggcag aaaagcatat taaagcagga gcaaaaaaag
    19201 taattataac agccccagga aaaaatgaag atataactat agttatcgga gtgaatgagg
    19261 aagaatatga taatgaaaag cacaatataa tttcaaatgc atcttgtact acaaattgtc
    19321 tagctccttt tgctaaagta ttggacgaaa aatttggtat agtaaaaggg ttaatgacta
    19381 cagtacattc atatactaac gatcaaagaa tattagataa aagccataaa gatttgagaa
    19441 gagcaagagc ggcggctgaa tctataatac ctaccactac aggagcagca aaagctgtgt
    19501 caagagtatt accacaatta gaaggaaaat taaatggttt ttcacttaga gtgccaacac
    19561 caacagtttc acttgttgat ttagtatgcg aacttaaaga aaacgttaca tctgaacaag
    19621 ttaactctgt gttaaaagat gctgctgaag gagaattaaa aggtgtttta ggatattgtg
    19681 acaagccact tgtttctata gattataaag gagattcaag atcatctatt atagacgctc
    19741 tatccacaat ggttatagaa gacaatatgg ttaaggtagt ttcttggtat gataatgaat
    19801 ggggatattc ttcaagaact gttgatttag taaaatatgt agctgaaaaa ttaaaatagt
    19861 atataattct tagaataaat taaaaaaaat tttttgaaaa aaattgtata aaactaaaaa
    19921 aaagattatg aaaaatattg aaggaaaaat tttttcataa tcttttttct ttcatgcaaa
    19981 agatacaagt tacaacttat atttgtatat taggtcgtta gagaagtata tatatattta
    20041 gtaaggaatc gtacttttta taaaatgaaa gataagatgt cgaaaacttg cataaatctg
    20101 aaaaattttt attattaaaa tactgatttt cattttaaat gtgataaaaa aatgacaaat
    20161 aaagttgcaa atagtaatac ttataagtat aattaaaaaa gagaaaaggt tttgttaaac
    20221 tttataacaa aagaaaaaga agggatgatt caaaatggag aagttaacag acaggagaca
    20281 ggttaaggca gtaagcatgg aaaccttcat tttcctaata ttactagtag ttggttttgg
    20341 gtatgttggt agtattatgg gtgcaggaat gatgttcaaa gtaataatga gtacggcaca
    20401 tgctttacta ttagagacag ttttcttaat tatggctatg gcggttcttg caggcgcatt
    20461 aagcgcacta ctttcagagt ttggagtaat agcgttaatt aataaaattt tcgctgtatt
    20521 tatgaagcct ttatatgggc tacctggtgc tagtatagca ggagctataa caacttattt
    20581 atcagataat ccagctatta taccttttgc taaagataaa acattcacac agtattttaa
    20641 acaataccaa gttccagcat tatgtaactt aggaacagcc tttggtatgg gacttatctt
    20701 aacaacattt atgatttctc aaggtacaga atatgtactt ccagcattaa ttggtaattt
    20761 aggtgcaatt ataggtagtg tcataagtgt tagaataatg ttgacattta ctaagaagtt
    20821 ttataaatac aatccggaag aagataaagc aacaggaaca ttagagaaaa aggatgaatt
    20881 tagagaaatc agagaaggta atgtatttca aagagcttta gatgcaattc ttgaaggtgg
    20941 taaaatggga gtagatatgg gaatggctat aatcccagga gtcctagtag tatgtacatt
    21001 ggtaatgtta ttaacttttg gaccatctac agaccctgtt acaggtaaag aagtttatac
    21061 aggagctgca tatgaaggaa taaaattact tccagttatt ggagacaaac ttggatttat
    21121 attagaacca ttatttggat ttacatcacc agaggcaata gcattcccta taacttcatt
    21181 gggagctgtt ggtgcagcaa tgtctctagt tccagagttt ataaagtcag gagctataac
    21241 tcctaatgat atagcagtat ttacagctat gggtatgtgt tggagtggat atttaagtac
    21301 acacattggt atgatggatg cattaaatgc tagacagttg gcaggtaaag ctattctttc
    21361 tcatacaata ggtggtttat gtgcaggagc agcagctcac tttatattta cactcatagt
    21421 ataaatgtaa tcagctaaaa taaaaaataa tatacaaaaa aatggttgtt gatatgtaat
    21481 aagaatttgc atatcaacaa ccattttttt ctggctaaag ataatttata atacgtaaac
    21541 attaagtgga tattagagtt aagttatatt tatgtaaaaa gtaacaaaaa tctgtagaaa
    21601 tttatgacaa aatttagtac actaactata tgttcttatt taaaatttga ggttagaatt
    21661 aggaattacc tagtagagta agatttgatt aataaaagaa tcataaaata aaaatattag
    21721 tcataaacat tataaataac ttacttaaaa taaagccata gaacttacaa aaattaaaaa
    21781 agcatataaa tatggagggg tacaatggat gaattatttc atataggaat tgatgtaggt
    21841 tctacaacgg tgaaggttgt ggtacttaat aatagtaata atatagttca taaagaatat
    21901 agaagacact attctgatgt gaaaaaatca gttaaagaag tactaaatgg tatatatgaa
    21961 agatttggaa acataaatac taccattata ataactggtt caggtggaat tggaatatca
    22021 aaaaaattag gcgtaaaatt tgttcaggaa gttatatcta gtacaaaatc aatagagtat
    22081 ttccatcctg aaactgatgt tgtcatagaa cttggaggag aagatgcaaa aataacatat
    22141 ctaagtggag gaatagacca aagaatgaat ggaatatgtg caggtggcac tggagcattc
    22201 atagaccaaa tggcatcact tttaaagact gatgccagtg gattaaatga acttgctaaa
    22261 gggtataatg ttatatatcc tatagcttca agatgtggtg tttttgctaa aacagatatt
    22321 caacctctta taaatgatgg agctaagcaa actgatatag caatgagtat tttcaatgca
    22381 gttgtcgtac aaactgtgag tgttctctct tgtggaagaa aaatagaagg aaatgttgcg
    22441 tttttaggtg gtccattata ttttttatct gaacttagag aagcatttaa aagagttttg
    22501 gatttaaaag atgaaaatat aatcttccca gaaaatgcac agctttatat tgctattgga
    22561 gcaggattat tatcagtaga tgagtatagt atacaactaa aatctctaat agaaaaattg
    22621 gatagtataa agaatattga agatggagaa gtaaatttat tagaaccttt gtttaaagac
    22681 aaaaatgagt atgaagaatt ttcaagaaga catgaaaagg aaaaaataaa ttatgtggac
    22741 ataaattcaa taaagagtaa ttgttatttg ggaattgatg caggctcaac tacaactaaa
    22801 gcagcactta ttgatgaaga tggaagactt gtatattctt attacaatag caatgaagga
    22861 aatccattaa aaacaaccat taaagtcata aatgatatat atgacatatt accaaaagat
    22921 gttaaaatat tgagttcaac tgtaactgga tacggagaag gtcttattaa aaaggctctt
    22981 aaaatcgata atggagagat agagactata gcacattaca aagctgctaa atttttcaat
    23041 aaagatgtag attttatact tgatattggt ggtcaagata tgaagtgcct aaaaataaaa
    23101 gatggagtaa ttgataatat aatattaaat gaggcttgtt catcaggttg tggctcattt
    23161 ttagagacat ttgcaagttc tttatctatg acaatagaag aatttgcaca tgaaggtatt
    23221 tattctcaaa atcctgtaga tttaggttca agatgtactg tatttatgaa ctctagagta
    23281 aaacaagctc aaaaagaagg tgcaagtgtt ggagatatat cagcggggct atcttattca
    23341 gtaataaaaa atgccttatt taaagtaata aagattagag atttaaatga gattggtaat
    23401 aatattgttg tacaaggtgg aaccttttat aatgatttag tgcttagaag ctttgaaaaa
    23461 ctaattggga aaaatgtaat tagacctaat atttcaggaa ttatgggagc ttttggttca
    23521 gcacttatag caaaagaaaa atatgaaagt ggatacaaaa catccttgtt atctaaggaa
    23581 gagttgaata atatcaaatt agaagcaagt gtaactagat gtaaagggtg ttcaaatcat
    23641 tgtcttctta caataaacaa attttctgat aatgaaattt ttatttcagg taatagatgt
    23701 gagaaaggtg aagctattta tggcgataaa aaaatagggt tagaaaagaa aaaaccaata
    23761 aatttattta agtacaaata taataggatt tttagataca aaccattgga aaaagaagaa
    23821 gcaaaaaatg gggaaatagg gataccaaga gtattaaata tgtatgaaga ttatccattt
    23881 tggttcactt ttttcaatgc tatgggcttt agagttgtac tttcagatag gtcatcaaaa
    23941 cagttatatg aaactggtat aactagtatt gcatctgaaa cagtttgtta tccaggaaaa
    24001 ttagttcatg gacatataga aaatttaatt gcaaagggaa taaaaaatat attttatcca
    24061 agtgtaacaa atgaaaataa agaggattca aatgcagata attattataa ttgtcctgta
    24121 gtaatatcat attctgaagt aataaaaaat aacgtagaga atataagaaa taagaacata
    24181 aactatataa atccatttat aagtctaaat gataaggaaa aattgaagaa aagactatat
    24241 gatgagttat caagacattt ttccgatata aaaataacta aagaagaaat taataatgca
    24301 gttgataaag ctactgatga acagaattta tttaaaatgg agatacaagc agcaggtgaa
    24361 agagcactta aagaaataaa agaaagaaat atgaagggta ttgtgttatg tggaagacca
    24421 tatcatatag acccagaaat aaatcatgga atgccagagc ttataaattc attagatatg
    24481 gcagtgctta ctgaagattc tatatgtcac ttagccaata tacaaagacc acttagagtt
    24541 gtagaccaat gggtatatca ttcaagattg tataaagcag ccagttttgt aagagataaa
    24601 aactatttgg aacttgttca acttaattca tttggctgtg ggttagatgc agtaactaca
    24661 gaccaggttc aagaaatact taatgaaaaa tcgaagatat atactattat aaagattgat
    24721 gaaggcaaca atttaggagc agctaaaata aggatgaggt ctttaaaagc agctatgctt
    24781 gagagagaaa gcaaaaacat agatgtaaaa aatataaaag taaataggat acagtatgct
    24841 aaaaataatc atataacgaa caaacatact atattagcac cacaaatgtc tccaatacat
    24901 tttcaattcc ttgaaaaagc tgttaactta agtggttata atatagaaat tctaaaagat
    24961 actgatagta gtgtaattga agaagggtta agatatgtaa ataatgatgc atgttatcca
    25021 gctataatag tagtaggtca gctaataaca gcattaaaat ctggcaaata tgatttaaat
    25081 aatacttctg ttactataac tcagactggt ggaggttgta gagccacaaa ttatattgga
    25141 ttcttaagaa aggctatgta tgatgctgga tttaaagatg ttcctgtcat tgcacttagt
    25201 gtaaatggaa tagaagatag tggtataatg gacaatatat cactaaaatt aatcaataga
    25261 ctctttatgt ctgttgttta tggtgatttg ctgatgaaag tactatatag agtaagacca
    25321 tatgaaaaag ttactggaag tgcaaatgct ctatatgaaa aatgggttga tatatgcaaa
    25381 acttctcttg ttaaagcaaa aatttctgta tttaccagaa atataaaaga tatagtaaaa
    25441 gaatttgata atttagagat actagatatc aaaaaaccaa aagtaggttt ggttggagaa
    25501 atattggtga aattccatcc aattgcaaat aataatttag tagatatatt agagcgagaa
    25561 ggtgctgaag cagtcgtacc agaccttaca aatttcttct taagttgtgc ctttaatact
    25621 atatacaaac acactcattt agaaggaagt agaaagagta gaatgatagg agaagtattt
    25681 atatacataa ctggaatata tcaaagagta tataaaaaag cacttgataa gagtgagaga
    25741 ttttatgctc cagccaatat aaaaaatgtt gctaaaagta cagaaccagt agtgtcatta
    25801 ggtaatcaaa ccggagaagg ttggctttta acaggtgaga tggttgaatt attaaatgaa
    25861 ggtgtagaaa acattatttg tatgcaacct tttggatgtt tacctaatca cataattggt
    25921 aagggttcta taaaagaatt aaagaggttg tataaaaatg caaatataat acctattgat
    25981 tatgaccctt ctgcaagtga ggtaaatcaa cttaacagga taaaacttat gctttctaag
    26041 gcttttaaaa atatataaga tttatatttt aatatgttaa aagttaatga atttaaaaat
    26101 atactctata ttaagtatct ataaaaaaga gttatcctat tttttagggt aactctttat
    26161 tagttaaaaa attatatgta tactgatatt aaagggggga agtaatatga gtttagtata
    26221 tgatgtttat aaatcaaaat taggaaattt gtacatatta agtgaagatg attttatagt
    26281 tagtgtatac ataggagatg aaaaatttaa taatttaaaa aatgaatata ttaaaaaagg
    26341 aattgatata aagagaagta aggaagattt aaaggaagca ataagtcaga tagatgatta
    26401 ctttaatgga aaaagaaaag tctttaattt aaatattcgt attgaaggga ctgaatttca
    26461 aaaatcagtt tatagggaaa tgttaaaaat accttatgga gaaacattgt gttattcaga
    26521 tatagcaaga aatataaata atccaaaatc agtaagagca ataggacaag caagtaaaag
    26581 taataaaatt ccaataataa taccttgtca tagagtagtt ggcaaaaaaa atattggtgg
    26641 atatatgggg aatcattctg atttgaaaga gatactatta aatttagaaa gacagagtta
    26701 acttagaaag aaatgttttt attgttaata tttgatataa taatattaaa aataagtatt
    26761 ttttacaaaa acaataaaga atttatttta atttacaaaa atgaggggga attttaatgt
    26821 gtgataaagt tatagcatca aaatatcatg agaagggatt taattgtgca gaatcagtta
    26881 taaaagcata taatgaagaa tttaatacag atataccagt ttgcctaggt agtggactgg
    26941 gttcgggttg tggagttgct agtttatgtg gtgcagtaaa tgcatcaaat ataataattg
    27001 gatacgtaaa aggcagaaac catgaagatg aaagtactag agctaaagta tatgctaaag
    27061 atttaactac aacagtaaga aaagagtatg gttcagagtt atgtatagac ctaaaaaaag
    27121 atttagttgc ctgtagagaa ataatggatt tcgcatatga tagtctaaag gaaactttaa
    27181 aaaaagaatt ataagaaaat aagctatcaa gtacaaatta tttgatagct tatttttata
    27241 gtctatacta aataaattaa acatatttta gaattattat ttgtaaataa acatcaaata
    27301 attttaggtt ttttatttaa tatagctttt tatttatatt tgtttttgaa tgtgttatac
    27361 tctgtttaaa taaatatttg taataaggga gatgagaaga ttggataata tcaatttgct
    27421 tattaataga ttatattcaa aaaatcataa tgaagcatat aaaacttttt tattcttaga
    27481 aaatgaaagc ttaaaatcaa atattacata ttgttttttt gactcattcc tagaaatgat
    27541 taataacgaa aactcataca ttcgagcaag aggattgtta ttaatttccg caaatgctca
    27601 atgggatatt gataataaaa ttgaaataaa tatagatagc atactaagtc atatcgtaga
    27661 taaaaaacct tttgtatcaa gaatgtttat taaatccata cctaatatta caaagtataa
    27721 aaaaaatctc attcgtcgca taaaaatgga attaagtaat gcagatataa gtatttataa
    27781 taataatatg aaaccattag tagaaaagga tataaacgat acattatcta atcttagtta
    27841 aatattaata tagaaattgg atattatcta gttgcaatta tttataagta aaataataaa
    27901 acaataatgg tgctaatttt tatagataaa ttaattatga aaaatttatg taagtaaaat
    27961 atattaacat aaaggtaaaa ttttgtacac taaaagggaa tatttacagt ttaatggcag
    28021 ttttgaaata acaagttaaa gctgtcattt ttatttgaaa atttttagaa aaagtacaat
    28081 cgtgttaatc tgttaactag ataaggttta tataataatt tggatgatat gatataaaat
    28141 atgttgtata ttaaatgttt tctttgacaa tatatattca aggatgataa tatctatatg
    28201 aataaaagct agcgtatcaa tttgataata tgtaattata acattatgct ataattacaa
    28261 taaagtatgt aataatctgt agaaattaca agttagttat ttaatttttc gaataactaa
    28321 atctaaacgg aatacataat gtactaaata aatgatgata ctaaaatgat actattttta
    28381 tagaaattta ttgaggtata taattaatga aaataatata ttaaattata taatatattg
    28441 agttttacat aaaagcgaag gtgggaataa aaatgaaaga aattgctgat gctataacat
    28501 cagagtattt aagctatggt atcaatgaag atattagtat ctatgaaggt agattttgca
    28561 tatatttaga taaaaaatat agatgtaatg ggaaaattta ttataaaatg acacctccaa
    28621 tatctataag ttttaaagca gagataggtt gtgttgaaga gatagacagt gaagatgaca
    28681 atttagcttt ggattatgat aatgctattc ttgaagttca tggatataaa attatttcta
    28741 taacaataaa tactttaagt gaatttagtg tagagggtta tatcaatgat gactgcataa
    28801 aatctaagaa ctcctatgtt gaatatgtag attttaatat aataaactta gataaaatac
    28861 ctggaaaact cattaaatac aatgataaag tatacgcagg tagaattgaa tttgatataa
    28921 atgattatgt tataactata gacaagaggt atgattatag aaaagaatta aaattagaat
    28981 taaaatctaa atctggagca ataataactc atataggtag aattagaaga aaagatggta
    29041 gaatttttag aacaaataat acaataaatc ttttagatag aatatcaaca gctttgagtt
    29101 ttatgtgtgg aagatatgta gggttttgtt tggccaaagg gtatagaagt ggtaatgaag
    29161 tttatagaat atggaatgaa aatcaaatat ctccttttag atatgtacca acatggtcag
    29221 atacactttc aaattatcat aatatggaaa aatatataag tcttatgtgt aaaaagctag
    29281 aagattttta ttatggttcc gctataaaga gtgttgttga ttggtatata gaatctcttg
    29341 gaagtgctac tatggaaaac aatataatat ctgtgcaaat tgcacttgaa actttgtcat
    29401 atgcaatttt agtagaacaa agtaaggtac ttacagatga agcttttgac tgtaatttgg
    29461 catctagaaa tataagactc ttacttgata cctgtaagat accatatggt aaacatgaat
    29521 taaatatatt tgataatata ataaaaaata aatttgatga tggagtggat ttagttattt
    29581 atttaagaaa tagcatagtt catccaagta gaaagactca tagagctgta ttagaagttg
    29641 aggatatttg gaatataatt tcaataggaa cgagatatat tgagcttgtt ttacttttta
    29701 ttttaggtta tagaggagaa tattcaaata gattagtaga aaggtgttat ggtgaagtgg
    29761 aagttgtacc ttggaactag atttttatat ttattttaaa atatatattg acatatatta
    29821 ccttatgcta taaaatcaat atcataataa caattcagaa taacattaaa tgctaagaaa
    29881 agaaatagta aaagtagtta atcttaaaca gagagtttcc gattggtgag aggagcaata
    29941 gattttactt tgaacacatc tttgagcagg actctgaaag agtagaaata ctttattagg
    30001 agctttccgg aatccttgca cccgttatag tgctagagta taatgatttg ttttattgta
    30061 cttaaagagg ttagtgtcgt gaggcattaa tgaacagagg tggaaccacg agagttaact
    30121 cccgtcctct agcagaagct agaggcggga gttttttaat ataatttttt aagcgcgcag
    30181 agaattatat tgcaagagat acacttttta aaaaataatc aaaatatttt aaaaattaaa
    30241 aggcgaggga gaatattatg aaaaatatat taaaaaaagt aggaatattt acaattatgt
    30301 taggtttatt aggtggagtt gtaggttgtt caaagccaga taatgaaaaa gataaggatg
    30361 cttcaaagga atctaaaaaa gaagtagttg taggatttga taatacattt gtaccaatgg
    30421 gatttctaga tgaaaaggga aatacagtag gatttgatgt ggatttagct aaagaaacat
    30481 ttaagagact tggaatggaa gttaagtttc agcctataga ttggtcaatg aaggaaactg
    30541 aattaaatga ttcaaaaact gtagatgtat tatggaatgg atattctata acagacgaaa
    30601 gaaagaaaat agtatcatat acagaaccat atttacaaaa taagcagata atagttactc
    30661 taagtgattc aaagataaat tcaaaagctg atttaaaaga taaagaagtt ggaacacaac
    30721 aaggttcaac agcacttgat gcagtggaaa aggataaaga ttttatgaat agtttaaaag
    30781 gtggagcacc agttctttat gatacttatg ataaagcact tagagattta gagataggta
    30841 gaactagtgc agttgttggt gatgaagttt taattagata ctatatggga caaaaaggtg
    30901 aagacaaata caaagtgtta aaagatgatt ttggattaga agattatgtt gtagcaactt
    30961 ctaaagaaaa tccagaactt tgtgagaaaa taaatgaaac attaaaagaa atgaaaaaag
    31021 atggaacttt tgacaaaatt tatgataagt ggtttaaata gaagataagt tagctgttaa
    31081 gaagggggca ctaaaggcat gttacaaggt ttagagatag ttatagcaat gttttgtata
    31141 acattgataa tatcaattcc attggggatt ggagttgcat ttttaagatt atcaaagaat
    31201 aaattagtaa gtggtattac acaatgttat atattgataa tgagaggtac acctttactt
    31261 ttgcaaatga tagtcatatt ttacggatta cctcttttag gaattgtatt tgacagattt
    31321 acagctggag tagtagcttt cttcttaaat tatgcagcat attttgcaga aatatttaga
    31381 ggtggaatac agtcaatcga tagaggacaa tatgaagctt caaaagtact aggatttgat
    31441 aaatttacta tgtataagag aataatcttt ccacaggttt ttaaaagaat actagcacct
    31501 atttcaaatg aagtaatcac attagtaaaa gatacatctt tagtatatat attaggatta
    31561 aatgatattt taagaatatc tcaaatagca atgaacaggg aagctagtct gttaccatta
    31621 tttgaggcag gagcgatata tcttatattt gtagctatac ttactaaggg atttgaatta
    31681 cttgaaaaaa aatattctta ttatagataa agttacaata ttataggagg aggtttttat
    31741 atgttgaaaa tcaaaaactt aaataaatca tttaaaaaaa atagagtact taaagatatt
    31801 tcttttgagt tagaagaagg tcagattgga gttttacttg gtaagtctgg tgcaggaaaa
    31861 accacaatat tgagatgtat aaatggtctt gaagaatttg atagtggaga gattataata
    31921 gataatgagg taataaaaaa taagagagat atggcaaaaa tacgagggaa aataggtatg
    31981 gtttttcaaa atttcaactt atttcctcat atgacagtcc ttgaaaatat aattgaatcc
    32041 ccagttaatg tttttaaagt tcctagaaaa gaggctgaag agagggctag agaactttta
    32101 agattagttg atttagaaga caaattaaat tcttatccat ttgaattgtc aggaggacag
    32161 caacaaagag ttgctatagc taggtcatgt gcattgatgc caaaagttct ttgttttgat
    32221 gaacctactt ctgcacttga tattgatact attcaaagag tagtcaatat aatgaacaga
    32281 cttaaagata aaggtatgac aatattaata attacacatg atgttgtctt ttcaaataat
    32341 gttgcagata aaattataag tataaaagat ggtatagtag aaaatgttca aataaaagaa
    32401 aaaattgttt agagttttat aaatataaac tagggtagaa ttttataata taaataatgg
    32461 gcaagtaaaa tcaaatatac tatgcccttt tgttgtctca aaatttaatc ttatatttta
    32521 tgtttaagtt acatttaatt tataataaaa ataaaaggac tatttaaata tataatgtaa
    32581 ataaatgttt aatttgaaac atgataattt tttatgttga aagcttataa tcattatgat
    32641 ataaattggt tatagtatac aaattatggg tataacaata aaaaattaga aaggaatttt
    32701 tataaaatga ttaaattata tggatataca aaatgttcta ctgttaaaaa agcaaaaaat
    32761 tggcttaagg aaaataattt agaatttgaa gatatagata tggttcaaaa tcctcctaat
    32821 aaagaggagt taaaatcaat ttataagacc agtggatatg atataaagaa attttttaat
    32881 acaagtggtg tgaagtatag agaattgggt cttaaagata ttgtaaaaac tgaatctgat
    32941 gataaacttt tagaaatatt ggtaagtgat ggtatgctta ttaaaagacc attacttttt
    33001 gatggtaaaa atgtattatt aggctttaaa gaagacgtat ggaaaagtac tttgctaaaa
    33061 gaagattaga aggatatagg tgtgttgatt aaaattatta attaatacac ctataaattt
    33121 atgtattaaa tctaattctt ataaatatta attagcaaat tcaaatcaaa aaaattcata
    33181 tcaacaaaca tattacttct tgttacaaat gatatcatgt attttattta aaatagtata
    33241 atattacaac gaattgttac aaaattactt attattaacc atgaacattt gttttgtgct
    33301 attatattta tataaggtaa ttgtcataaa aaatatcttt ttcatacaga tttatataga
    33361 aaaatgaaat gaatatttgc tttatataag tatattttgt aaattgactc tatatttata
    33421 gtttaaataa tagtggtatt aaaaatctga caacaaaaat aaaactttca aaaaattaaa
    33481 tctaaaaaga ataggaaata aatatgagta ttgaagattt atatgatttt gaatgtgttc
    33541 ctttgaacaa tgaggttgat attgatgttt tatttgaaaa gatgatagaa gatggaaaag
    33601 aaaaagaata tacaccagtt atagtcattg acgaaaaagt agggctatta agaaaaaata
    33661 tcgatataat tattaaagag tatggttctc ttgaaaatta tagagagtat tgtttaacaa
    33721 aatacaatga aattgatgta aaccaatttt ttgattttag gaagcgtgag atttcagaat
    33781 tattaaagga gctagttgat ttagaagatg atttttatga ttataaacat tttagaccaa
    33841 ttatgaatat agatatattt catgaataca ataaaattta catagctaaa gttccaacaa
    33901 ttaaaccata cgaagtattt gcatacatac ctattggtgg atttaatgat tgtcctagag
    33961 atgaagaaca catagctatt gcaaaatatt ggtatgaaaa acatggaatc tttccaattg
    34021 caattggatg tgatacagtt caatattctg taaaagattt aattaaagat ggtaaaaaat
    34081 ttgatgaatt atgtattgaa ttagtatttt attgtgagga tattattata caagggtatg
    34141 aaaccttaaa tgctcttaag gatgtattaa aacgctctac aatattgctt ttttggtggg
    34201 attgatataa tcaattaaca tattgtaaca taggtttgag gaaggagata taaaatatcg
    34261 ttagaacttc gtgtactaga gttacaaact tgtacttcag ttgtaggtaa atgatgagtt
    34321 ctttatgact tttaaacata ttactatgtt acactaggtt tttatacaca gtgtagcgca
    34381 gtaatatgtt taaatttata aagatttaaa aaatactttg atattataat ttataaaata
    34441 aatactttat atgttataat cattaagaat gtaaaaaata atatatagtt ttatagttca
    34501 tgtttttcta gatatggagg taaattttgt gaaggaaaaa gaaaaattag ataaattaaa
    34561 aaaaatgtta cttgaattag gaagtgttgt agttgcttat tctggtggag tagatagtaa
    34621 ttttttgctt aaggtcgcaa aagatacatt aggtgaaaat gttgtagctg taactattca
    34681 tgcaatgatg cattcaagta gagaaattga agaggccaaa caatatactc aaaattttgg
    34741 tgttaaacat atcatattaa atatagaaaa ctttgattta aaagaattta aagaaaatgg
    34801 tattgataga tgttatcatt gtaaaaaata tatattctct aaaataaaag aggtagcaaa
    34861 ggaacataat ataaagtaca tagtagatgg gacaaatata gatgatttag gagattatag
    34921 acctgggctt aaggcactga gtgaattagg agtaattagt ccattaaaag atagtggttt
    34981 aaaaaaagaa gaaattaggt cactttcaaa aatattagga ttaaagactt ttaataaacc
    35041 atcatttgct tgtcttgcaa gtagaatccc ttatggagtt gagataacag atgaaaattt
    35101 aagaataata gaaaagagtg aagaatattt atccaattta ggtttttctc aatttagagt
    35161 gagaatgcat ggagatatag ctagaataga agttggacaa gaagaattag gtaaattttt
    35221 tgaaaataac aactttaata aagttgatac taaattaaaa atatttggct ttaaatatgt
    35281 tacactagat atgtcaggat ataaaatggg aagtatgaat ttaaatgtgt agattatttt
    35341 aaaaataaat aagttttata gttaagataa agaaacagga ggttttatga aaaattatac
    35401 attaatatcg ccatgttttt ttggaatgga aaaaatgctg gctagagaga ttactaattt
    35461 aggatatgaa ataataaaaa cagaagatgg aagaataaca tataaaactg atgagtttgg
    35521 aatagcaaag tcaaacatgt ggttgagatg tgctgaaaga gtacatctta aaattgctga
    35581 atttgaggca aaaagttttg atgaattatt tgaaaataca aaaagaataa actggtctag
    35641 atatatacct tatggagctc aatttcctat atcaaaagct tcctctataa aatcaaaatt
    35701 atacagtaca ccagatgtac aagccatagt aaaaaaggct atagtagaaa gcttaaagaa
    35761 aagttatttg gaagatggct tgcttaaaga agataaggaa aaatacccta tttttgtatt
    35821 tatacacaaa gataaagtaa ctatttctat agatacaaca ggagatgctt tgcataagag
    35881 aggatataga gaaaaagcaa ataaagctcc aataagagag actttagctg ctgggcttat
    35941 ttatttaact ccatggaaag caggtagagt tttagtagac cctatgtgtg gttctggtac
    36001 tatattgatt gaagctgcta tgattggtat aaatatggca cctggtttaa atagagagtt
    36061 tatatcagaa aaatggagaa ctcttgataa aaaaatttgg tgggatgtaa gaaaagatgc
    36121 ttttaataag atagataatg aatctaaatt taagatttat ggatatgata tagatgaaga
    36181 atctatagat atagctagag aaaatgctga aatagcaggt gtagatgaat atatagagtt
    36241 taatgtagga gatgcaacgc aatttaaaag tgaagatgag tttggattta taattactaa
    36301 tcctccttat ggggaaagat tggaagataa agatagtgtt aaacagttgt ataaggagct
    36361 tggttatgca tttagaaaat taaaaaattg gtcatattat ttgataacat cttatgaaga
    36421 ttttgaatat gagtttgggc aaaaagcaga taaaaaaaga aagttgtata atggtatgct
    36481 aaaaactaac tttttccaat atccaggtcc taagcctcct agaaataata aataagtttt
    36541 acatgattca tttgtaaaat ataaaatttt attaaaataa gtaaaacatt atgacgcctt
    36601 gaaacgtcta attattgtga ggagattttt gtgaacaaat ttaaagattt ataggattag
    36661 gaggagttaa atgaaagtgt taaagcttat tactgtagta gccatgatga tgttatttgt
    36721 tactgggtgt aatataaaaa ctgaatctcc agaacaatta gcgaagatac ctaactatga
    36781 tgatacaaaa aaagtattgt atgatggtat tgaccagtta ttaaaaccag attcatctat
    36841 gatattgcct tctaatacaa aagaagtagg aaaaataaat aaggtagatt taaacagcga
    36901 tggaattgat gaattagtag tatttgaaca aaaagaagat ttaagtaata atgtgagtca
    36961 ggtagggttt gtaaccttga gttacaatgg agaaaaatac gtacttggag accatttctt
    37021 agaaaatggc gaatcaatag aatatgctaa tttttatgat ttagactcag atggatataa
    37081 ggaagttatc ttattagtta aatccaaaga taaaacaaat atgcatatat ataaagtagt
    37141 agataatgaa ataacaaaaa tatatgactt ggatgcatca tggcttcaaa ataaagaaga
    37201 ttttaatgat atgaaagtaa aaattggata tatagatgga gatgacaagt tagatatatt
    37261 gatgcttcat ttaaataata agactaatga aatgtttgca agtgttgcaa atttcgatgg
    37321 gagtatgaaa atcaaagatt ctgttaagtt tgaaaatgta aaaaacctaa gtgaactata
    37381 tataacatta ggtaatgttg cttcgtctgt tggaaattct tcggcagcta taaaaggtat
    37441 tgtacttgat atccctatat tgaaagataa taattatatt actcagatac tttatatgaa
    37501 agatggaaaa attaacaaag cttttagtga ttatgataaa actattacta aatcttatta
    37561 tatacctgta gatgatattg ataaagataa gattatagaa atacctatag ttgcaggtaa
    37621 tacaggtaat aatagaaata cttatagttc taaagcatct gcaaatataa gttggtatag
    37681 atggaatgga aaagaaggtg ctgattcaag tttaatattt acaagtcaga tatattataa
    37741 ttataaatat aattttaaat tatttattcc aaataattta tttgataaaa tacttgttga
    37801 acaagaattt gttggagaaa aggcagtatt taaattttac tattttgact attcagaccg
    37861 taagaattta tttaatatag tagtagagag taaaaacaaa cttgaagata gaaaaaatac
    37921 aagtactcaa aattctattg tacttcaaga gagcgatgaa tatactttct tactagttgt
    37981 aaacaatgca aatgaaatgg ataagctaga tatgactata gacgcattaa aagaatattt
    38041 ctcattaata tatggttaat attatactca attggaggtt ttattttatg aaggaaaaaa
    38101 tacttatact agaagatgaa attggtatta gaagttttgt tagtataaac ttaaaaagag
    38161 aaggctatga gatagttgag gcaggtactg gaagagaagc tatagaaaaa atgacaacag
    38221 aaaatgatat tacaatagct cttttagatg tgatgcttcc agatataagt gggatagagg
    38281 tatgtaaatt tataagggag aattttgacc aagtaggtat aataatgctt actgctaaag
    38341 ctcaagagga tgataaaata gaaggattta tttcaggtgc agatgattat attataaaac
    38401 catttagcat aaaggagctt ttagttagag tttctgctct tattagaaga gtagcaaaag
    38461 atgattcaag tgttaaatca agtgaaatag tatctccacc atttatactt gatatagaca
    38521 aaagaaaatt atttaaaaat ggaaaggaaa ttgagcttac accaactgaa ttttcaatag
    38581 tgaaatatct aatatcaaat gctaagcaat cgttaagtag agaccaaata ttagatgaag
    38641 tgtggggaac taattattta tatgatttta aaatagtaga tgtaaatata agaaggataa
    38701 gaaataaaat agaagatgac ccatcaaaac caaaatatat acaaactatt tggggttatg
    38761 gatactgttt tagaaaggaa gaataatagt gttacatttt gaaggtctga gaaaaaaagt
    38821 aataaaaaac tattttataa taattattat aatggttact ctgtttgaag gattgttcat
    38881 gttttacata caaaactact attatgattc tgtcaaacaa ctacttgaat ctgaaataaa
    38941 atatgctgat gaatataatg ctattacaat ggaaactaca agttttgaga aaaaagtaaa
    39001 aaatatattt gataaacaac ctttaactaa aaattcagaa tttggaattt caataataga
    39061 taaggataaa aatattatat tagaccaata tggctttaaa agcaaagaaa aagcaaacta
    39121 tgaagatgtt aacaatgcat taaaagacat aaaaactaaa aatttaacac catatactta
    39181 tagaatacca gatacagggg agcatgttat gagtatctcc ttaccactta aagtaaataa
    39241 tataatagaa ggtgttgtta gatatacagt atcattagat gctattgata atgcgatatt
    39301 aaagcaagct acatggctta tattagcagg aatatttata cttattatag ctatactaat
    39361 aagtcttaaa tttgctgaga ctcttataaa accattacga gagttaaaga aatttgcaaa
    39421 tgaattggct gtaggaaatt ataatataaa attagaaaag atgaagattg tagatgatga
    39481 aattggtgat ttagcacaga catttgaaca tatggcacat gagattgaca aaagtgaaaa
    39541 attaaaagaa gaatttatat catctgtatc tcatgaacta aggactcctc ttacatccat
    39601 aaagggatgg agtgaaacct taggctatga aagtataaca agagaagagt tagacttagg
    39661 tttaggtatt atacaagatg aaacagaaag actcataaag ctagttgaag aattattaga
    39721 cttttcaaga ctttcttcag atagaataaa gcttcatgtt gatatagttg atgttgaagg
    39781 tttaatcgta ggtgttgtaa atcaacttaa agttaaagca gccgaaaaag atatatcact
    39841 tttgtttgaa tttgaaaatg aatttataga gaacatccaa ggagataaaa atagattaag
    39901 acaggttctc ataaatttaa tacaaaattc atttaaattt actagtcaag gtggttacat
    39961 aaaagttgta gcttttcaag atgaagagat aacaaccata tcagtagagg ataatggttc
    40021 aggtatagaa aagcaaaatt taaataaagt tttagataaa tttttccaag aagattataa
    40081 taaggctggt agtggattag gactagcaat tagtaatgaa atagtaaaac ttcatggtgg
    40141 aagaatgaaa atagaaagtg aaaagaatgt tggaacaaaa ataactttta atataaaaaa
    40201 taagtttgct aaacaagcat aaattcttag aaagaggatt aagatgagaa acataaaaat
    40261 gatagtagca tatgatggtt caagatataa aggatatcaa aaactaggtg acaataatat
    40321 gactattcaa gaaaaacttg aaaatgtctt aagtaaaatg actaatgaaa cagtggagat
    40381 aatcggctct ggaagaactg atatgggagc ccatgcaaga ggacaagttg taaattttag
    40441 aactaattgt atggattctt tggataaaat tcaaaaatat ctatatgaat atttaccaga
    40501 agatatagtt gtaaaagctg ttgaagaagt tgatgagagg tttcattcaa gatacaacgt
    40561 aaaatcaaag acttatatgt atagaattga caataataag tatcacaatc cttttataag
    40621 aaaatatgcc actcatgtaa gtaaaaaatt agatttggat agaatgagaa aagcaagtga
    40681 gtatttagta ggagagcatg attttactag ttttgcttct tctaaatcta agaaaaaatc
    40741 aaatgtaaga gaaatttatt ctataaatat aaaagaagat gataatatta tagaaatata
    40801 tgtagaagga aatggatttt tgtataacat ggtaagaata atagtaggtg ctctaataga
    40861 tgttggtcta aaaagaagag ctccacaaga tattaagtat atgcttgaat caagagatag
    40921 atgccaatca tcagacactg caccagctaa aggactatgt ctttggaaag tgagatatta
    40981 gtcaattata taaagctttc tttaaaataa aaataaaata aattatatag ttgacataaa
    41041 tggaaaaata aactattata tattttataa gagagatata aaactttata tttaaatcct
    41101 gtgagaaaga gagtaacttc tatgtgtttt atagagagct gaggatggtg gaagcttagc
    41161 aaataagtat tagtgaaaag aactttggag gatactaatt gaatttagta tgttagtagg
    41221 taatctcgcc ttaagagaaa gagtggataa gtttatctta tcaattagag tggtaacgcg
    41281 gatatatttc gtctcttggt ttttccaaga ggcgtttttt aatatattta attactagtg
    41341 tttatttagt atgttgaaca tttactaatt gattagctaa gtttatcaat aagagtggta
    41401 ccgcggatat ttcgcctctt agtattttaa aatactaagg ggctttttta gtattaaaat
    41461 gattttatgt gaatctaaat tctcaaagtc attcaatatt aagaatttct ataaaataaa
    41521 aattataatt taagattggg aggaattaaa aatgaaggaa aaagtagtat tagcatattc
    41581 aggaggactt gacacatcaa tcataatacc ttggttaaag gaaaattatg aagatataga
    41641 tgttatagct gtttgtggaa atgtaggtca ggaagataaa atggaagatg tgtatgaaaa
    41701 agctttacaa agtggagcat caaaggcata tgtggatgat ataagtgaag aatttgtaac
    41761 tgaaactata tttaaagctg taaaagcaga agctaaatat gaaggaaagt atttattagg
    41821 aacttcttta gcaagaccta taatagccaa aaaattagtt gaagttgctc ataaagaagg
    41881 tgctaaatat atatgccatg gatgtacagg aaaaggtaat gaccaagtta gatttgaagc
    41941 tacaattgca gctcttgacc cgactataaa agttattgca ccttggagaa tttgggatat
    42001 aaaatcaaga gaagatgcta tagactatgc tgaaaaacat aatataaagg taacagcaac
    42061 taaagctaaa atatattcag tagacgctaa cctttggcat gtgtcaacag agggtggaga
    42121 tatagagcat ctagaaaatg aacataaaaa agatgtttac aaacaatgtg tagacccaga
    42181 agatgcatgt gatgtggctg aatatgtaga aatttatttt gaaaaaggtg tacctaaaaa
    42241 ggtaaatgga gaagaattat ctccagttgc actgattcat aaattaaatg agttaggttg
    42301 taaacatgga attggtgtta tagatatagt tgagaataga cttgttggta tgaaatcaag
    42361 aggtatatat gagactccag gaggaacaat cctttatgaa acacataata ttttagaaag
    42421 tgctacttta gacaaagata cattacattt caaacaaatg gtgtcttata aatatggaga
    42481 acttatttac aatggattat ggtattgtaa attaagagaa tctatagatg catttatgga
    42541 gcaaactcaa gataatgtta caggaacagt aaaagttaaa ctttacaaag gtaacataaa
    42601 acctgctgga atatttactg aaaatgctct ttatgatgaa ggaatatctt cttttggaaa
    42661 tagtgaactt tatgaccaca aagatgcaga aggatttatt aatttattca ctttaccatt
    42721 aaaaatcaga gctatgaaag ctggaaaata ataaaataga ttattcaaga gtatgtaaaa
    42781 acgatttcta ggtttttata tgctcttttt tatttggaat tattaaatta tgcagtaaac
    42841 aatataacaa aatatattat agtatcaaat cggttattaa tatgaaaata taatacctaa
    42901 aatataaatt ttataaatat aatagttatc tattgactct ctcattgtaa gagggtttat
    42961 actgaatcta gcaaaaactt atagtgagga gatagattat atgagaaaaa taattgaaat
    43021 caaacatcat tcacatgatt atgaatgtat gtggaatggt atagaagatt tatatataaa
    43081 taaaacaggt gaatgtcttc caaacaattt tttctttttg ctatcaggtt ttggttcgtt
    43141 ttgttatatg aaaacaaata aatcggagtt aaaaagaatg gtagctttgg gagatggaag
    43201 gacaaaaaag atgtataaat tcttagcacc aattgtcggt tttgaataca aacatcatga
    43261 gtttaaaaaa tatgagcaag cattaaagaa agcaaaatct gaaattgata gtggacatcc
    43321 agttgtttta ggagctttag atatgtatta tttaccatat tataaaaagt tatatcatat
    43381 agagcatctt ccttttcact atgtattaat ggtaggatat gatgatgaaa aagtatattt
    43441 gtatgattgt gggagaacag aattattaaa tctttcttat gataaattac gtgaaagtat
    43501 gaattgcagt tatcctggat taagcaaaga aaatactatt tgcacaataa gaatgaacac
    43561 ttcaaaaaat aaatataaaa ttgctaaaga agttattgct ataaagcgtg atatgttttt
    43621 aaatccacct aaaggatttt tgggatataa aggttttgaa aagtttatta aagagttgtc
    43681 acagtggaaa actgaattgg agaaagatga ttatgataag attttgacca atatgattat
    43741 gttttttgga acagtaccaa caattccaaa tgcaatcaaa ggaattaaag aaccagacac
    43801 tattcaattt aaaggtggat ttgacaaaat gagtaaaatg cttaaaagta ttggagagga
    43861 atataaaaat gactctttta tacaagtagc tgagattttt gataaaactt ctcttataat
    43921 cgagaaaata tccaatatta tagtagatta tttgactcag aaatatgatg atacagacca
    43981 acttccatta ctattctctg aggttttaaa ggatatgaaa acaggatatt taatattgaa
    44041 tgtataaaaa tagattattg actctaacat tacgtaatag tgtaatatga aaatatagct
    44101 tgaatagatt cgtaaaggtt gatagctata aaatcaaatt tgaggtgtag atatgagaac
    44161 agtaaaacaa gtttccgatt taactggaat aagtgtaaga gcattacatt attatgatga
    44221 aataggtctt ttaaaaccaa ataaaattac agatgcagga tataggcttt atgatgatga
    44281 ttctattaaa actcttcaac aaattttatt tttcaaggag attgatattc ctttaagaga
    44341 agttaaggag ataatgtcaa gcccgtattt tgataagtta gaggctttaa aaaatcaaag
    44401 aaaattactt attttaaaac gaaaaagatt ggacgaattg atagaactta taaatcaaac
    44461 cctaagggga gaaggaaata ttaattttaa agagtttgat atgagcgagt attttgatgt
    44521 tttagaagaa tttaagagag agcataagag taagataatt aaaatttatg gtagtgtaga
    44581 aaaatacaat gaatatatag aaagagttaa attcaatgaa gataaaattg ctaaaatggc
    44641 tataaaacaa tatggaacta ttgagaagtt tgcccaagct ataaaaacaa attttagcag
    44701 tgatatattg aatttaggag aaaaattcga tagatacaaa aatgattgtt taaaagagca
    44761 acatccaaaa ttaaaagaat tatatagaaa gcttgctgaa gatttaagca aaaatccctc
    44821 ttcaacagaa cttcaagaaa tagcaaagga gataacagat atatctaaaa aagattatga
    44881 aattttctct atggatactg gtgatgacaa ctggtattat atggttcaaa attatctggt
    44941 aaatcctatg tggatagaag aagtagataa aaagtatgga agtggagcag gcaagtttat
    45001 tggacaagta ctaaaaactt atctaagaga tagaaaacca aagataaata cattgtatga
    45061 aaaacttgta gaagatttga gtagagattg ttcttcaaag gaaattcaaa gcattgttga
    45121 agaaatagac aatgaaatga aaagaagtaa tgacttttat aaaatagaca atggagaaag
    45181 atactttgat tatatgtcag agctttattt acaagattct aactacataa aagtaactga
    45241 caagaattat ggtaatggtg catctaagtt tattggagaa gcttttaaga tttattttga
    45301 taataataat tgttgaaaat ttggaaataa aaaatgtgta agcttcataa aagcataaaa
    45361 gtaaggatat agattagctc catctatatc cttatttaaa gtcattaaaa tatataattt
    45421 acatcaaact tgacactttc aatgatattt cccagatatg tttttatact ttcaatttct
    45481 tctaaagatt ttaatttatt ttcagtataa attgctttgt ccagaatatt aaatcttaat
    45541 cctatttcat caaagtactc atgatttaaa actttgtacc aatggttttt ttctttattc
    45601 caacttgtag atattgaatc agcttctttt tgagcttttt cccaattttc attttctata
    45661 gatttttcta aaacagatat attgttttta tatccttctg taaaatcata tagtttattg
    45721 ttaacgtaaa atccaaataa tacaaataag atagtccata gtataacaaa tgttgtagat
    45781 ttcaatatta atcacccttt ttattttgaa taaatatttt gtcattttca tctaaaacac
    45841 aaataagaac atctttaaaa gtttctatgt gattagattt taaaataccc attaaccagt
    45901 tagtatcttt ttgagctatg tctagatttt tatttattat tctaccatcc agtataagtg
    45961 gaataggtaa atgattaaaa gctcttggag gagtactatt gtagcttgat gctggtacaa
    46021 cacttagatt accatcagtc tccaaaatag catactgtac atcttttagg ttaaagtatc
    46081 cctgaatcct aagttgctcc aataattcat ctatactaac tctttctttt ttaagctctt
    46141 tatatacaat ttttccctta tctattaaca cagaaggttt acctgataaa aatgaactta
    46201 attttctgct ttttaatgat aagaatgaaa ttagagtctg cataattaca agtccagata
    46261 ttgctgcaac accatttata attggtatat tattattttc cattgggaca gatgcaactt
    46321 ctgcaattaa tagtgttata actaaatcaa aacagttcat ttcagctatt tcaccttttc
    46381 ccatgactct aagtgcaatt agcactgtta tgtataatat aatacttctt attaatacta
    46441 ctgtcatatc tatcaattac tcctttaaaa aatatttaca cttagttagt atgtcctata
    46501 taaaaatttt aattcaaagt ataaaaaacc ttaaataatt ggattcaact acttaaggtt
    46561 tttttgataa ttttaatatt aaatttttta tagattttct gttactttta tt
//
LOCUS       DBGJFK010000026        46515 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.026, whole genome shotgun sequence.
ACCESSION   DBGJFK010000026 DBGJFK010000000
VERSION     DBGJFK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46515
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.026"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(58..822)
                     /locus_tag="ACOIAP_001709"
     CDS             complement(58..822)
                     /locus_tag="ACOIAP_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGZ2638595.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSRPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            1095..1769
                     /gene="fsa"
                     /locus_tag="ACOIAP_001710"
     CDS             1095..1769
                     /gene="fsa"
                     /locus_tag="ACOIAP_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGZ2638596.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSATVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(1891..3285)
                     /locus_tag="ACOIAP_001711"
     CDS             complement(1891..3285)
                     /locus_tag="ACOIAP_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGZ2638597.1"
                     /translation="MGIILKPKQFYITVIATIILYFSLNYNFNIKFSICLSFLTILIW
                     AIDSVEKTVVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFVSHENLEVNKIQFSYSNFKKELNLLNKEQKYVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     RENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWRFIGLEI"
     gene            complement(3364..4710)
                     /locus_tag="ACOIAP_001712"
     CDS             complement(3364..4710)
                     /locus_tag="ACOIAP_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2638598.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLRLMNTPESVFSQSKLYLTIIFGGILFSAGYNSVSAILRGLGDS
                     ITPLYFLIIATILNIVLDLTFIVVLKMGVEGVALATIIAQAVSFIISIIYLNKKHEVL
                     KFKIKGIIYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVIVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSRFFGTNGIWMGIPFGWTLGLIVTVIYYNKGRWKTKAIVNHRINK"
     regulatory      4960..5062
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            5156..6532
                     /locus_tag="ACOIAP_001713"
     CDS             5156..6532
                     /locus_tag="ACOIAP_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGZ2638599.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEVIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCIGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFM
                     NPEHAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPKNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSIVMIVLAIL
                     FIIKLWLL"
     gene            complement(6634..7779)
                     /locus_tag="ACOIAP_001714"
     CDS             complement(6634..7779)
                     /locus_tag="ACOIAP_001714"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGZ2638600.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAEISVT
                     SLALIGEVNIQKQIKNIKSVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKTLTATNPKRAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MAKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRNGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELVDIIK"
     gene            8031..8738
                     /locus_tag="ACOIAP_001715"
     CDS             8031..8738
                     /locus_tag="ACOIAP_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638601.1"
                     /translation="MLKVINLSKSYKNKKVVNSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFENGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            8785..10380
                     /locus_tag="ACOIAP_001716"
     CDS             8785..10380
                     /locus_tag="ACOIAP_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638602.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKSDGREKQKIMGMILSAIIITG
                     LLIFYVTTLSLSLVDILKQINQMEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDI
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFMFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKIYPPIYYFVDALKTGSVVSFLAFIAISIIPFFMFVTLFAKKFKNINAK
                     MSEGYKSKTYKFKSQKTSRPSKALLKKEFKRYTSSFIYFLNSSASLLFLIVGAILILL
                     FGADKMGELLKLNIDFNFIKIQLLGVFFFIIVMNCTTYCSISLEGENLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMVITMLVSLAYVVILGGIYTLLGISFLNIYIILASML
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            10483..11565
                     /locus_tag="ACOIAP_001717"
     CDS             10483..11565
                     /locus_tag="ACOIAP_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HGZ2638603.1"
                     /translation="MRKLSKKEKDFIQYGFLLFLICITTYLVLTTLDIKMIPKIIRLV
                     NKTYIFLGILIIIIYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLIEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKMFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYIHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSSIIPKELLGYSVLLYSGFVYYFILIVSGIFTFG
                     THYTLNSWKKETKVNSNLDKVIEKLN"
     gene            11714..11875
                     /locus_tag="ACOIAP_001718"
     CDS             11714..11875
                     /locus_tag="ACOIAP_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HGZ2638604.1"
                     /translation="MKQDKKNEKQSEISKIKQSNDNKLEVAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            12217..13485
                     /locus_tag="ACOIAP_001719"
     CDS             12217..13485
                     /locus_tag="ACOIAP_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGZ2638605.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            13679..14467
                     /locus_tag="ACOIAP_001720"
     CDS             13679..14467
                     /locus_tag="ACOIAP_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HGZ2638606.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSNLNLDYIKEDEDCVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMKQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASRDYRKAMSKVLLKRAIMEVI"
     gene            14467..14916
                     /locus_tag="ACOIAP_001721"
     CDS             14467..14916
                     /locus_tag="ACOIAP_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HGZ2638607.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKAGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRVLDREITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVIAMKDELENPTDEEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            14920..17184
                     /locus_tag="ACOIAP_001722"
     CDS             14920..17184
                     /locus_tag="ACOIAP_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HGZ2638608.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAVDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNNTVVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDIVIEETYYTQAQAHAMMETYRAYNYLDHTGRLVVV
                     SSTQIPFHVKRHLSRALELPSSKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKIDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKYLDNGKVRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLETSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGANKLGVDKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDKE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGHMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMAMNK"
     gene            17324..17632
                     /locus_tag="ACOIAP_001723"
     CDS             17324..17632
                     /locus_tag="ACOIAP_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638609.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKAKVFFKEK
                     QNQIEIDFVEEEISKLIENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGRVH
                     "
     gene            17918..18418
                     /locus_tag="ACOIAP_001724"
     CDS             17918..18418
                     /locus_tag="ACOIAP_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGZ2638610.1"
                     /translation="MRKNNINIALTSAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLI
                     IASLWPTIINSIVVGLMLNIFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     IINIKF"
     gene            18471..19457
                     /locus_tag="ACOIAP_001725"
     CDS             18471..19457
                     /locus_tag="ACOIAP_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638611.1"
                     /translation="MSKIKRLTDVWTYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMAMLFALKSLQVYNYKSIEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANNSNDGEFKSINVTEFFRASSESLILNIKY
                     KFGNQILEKKICPIGIYLNKGAWFSPAYDCKIDKIILVHIDNVIDIKRTGESKKIHIN
                     LEEWLDEVYNNLYENRSTTKKIGETIYLNVLLTKEGVSKIKDSSYNLDMELNEDGSGT
                     ISTFIRVEDVDYYASILFLIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            19507..20229
                     /locus_tag="ACOIAP_001726"
     CDS             19507..20229
                     /locus_tag="ACOIAP_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HGZ2638612.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEIEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIKEIIKAISYMSNERRVLSIGMDCSEKENKEALE
                     LGREFKINNDSIFKFVNLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKEYSEMADILFDRMEYIGEEFISKKGIVFVEGSSEFSIMELNDLINNIQRKIEESYE
                     VIFSLYMKENLDGNIRIGLLYN"
     gene            20258..22192
                     /locus_tag="ACOIAP_001727"
     CDS             20258..22192
                     /locus_tag="ACOIAP_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2638613.1"
                     /translation="MSENIRVTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFGMGKKSEKYINENCNDKDFIKRFVSIKKGDYFLYKAYQNIEEKVKCNVSIGMVEE
                     DFENGYELSHILGHTLPVKWMYNFDTVSNCKVYTSEFYKLNNNDISSYLEIINSQDKK
                     SLRKRIEESENNKWYLKNYYYKNVDKCVNDEELFIQPTNLEQLENIKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSTLEDGYFFPVRWIEYEKENIDGNAWV
                     IFENNSMVEKYVKRFTNKIPLNTILYGPPGTGKTYNTKQMVYNLVNKTSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYDALKFEKKM
                     SFELEKDSLTLEAIKKRKKKLVLENIEYSDSFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFFLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPNYDLLSIIDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEELIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            22185..23453
                     /locus_tag="ACOIAP_001728"
     CDS             22185..23453
                     /locus_tag="ACOIAP_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGZ2638614.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENIILEILPKLSLSDNLVKDREILLQMLSICNKIPII
                     MNEKIRLSLKNYNLLNFFIMYFIESMQIQMKKGIYFEYINKIENLNVIRGKILLSTYA
                     KEKCISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILNYFQNVD
                     LIYIDRKKLLDYKFCKNNDRFRDCYLLARLLLLNLSMDNSQDNEEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKSEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITTYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
     gene            23771..24811
                     /locus_tag="ACOIAP_001729"
     CDS             23771..24811
                     /locus_tag="ACOIAP_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2638615.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFARIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKIIE
                     YFKLNNINIKLLEENDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            25167..26489
                     /locus_tag="ACOIAP_001730"
     CDS             25167..26489
                     /locus_tag="ACOIAP_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGZ2638616.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWSVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            26786..28147
                     /locus_tag="ACOIAP_001731"
     CDS             26786..28147
                     /locus_tag="ACOIAP_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGZ2638617.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGAQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSVTSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            28220..29614
                     /locus_tag="ACOIAP_001732"
     CDS             28220..29614
                     /locus_tag="ACOIAP_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2638618.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKRVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMIELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNIILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            29676..30146
                     /locus_tag="ACOIAP_001733"
     CDS             29676..30146
                     /locus_tag="ACOIAP_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HGZ2638619.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLARNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            30149..32365
                     /locus_tag="ACOIAP_001734"
     CDS             30149..32365
                     /locus_tag="ACOIAP_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HGZ2638620.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGALRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAIKLIKVEYEELPAVFTIQEAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKELGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKRMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLITGAHDMGNGVVTMQTMMVAEILGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKVLILEEAEKLLETSKEDLYLDNGYVISKL
                     NENIKASLSDVAVYSQSKSLRELTVVEDYSSPTGLTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVNSYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            32445..33116
                     /locus_tag="ACOIAP_001735"
     CDS             32445..33116
                     /locus_tag="ACOIAP_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2638621.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            33479..34693
                     /gene="dpaL"
                     /locus_tag="ACOIAP_001736"
     CDS             33479..34693
                     /gene="dpaL"
                     /locus_tag="ACOIAP_001736"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HGZ2638622.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGKYLAQRLDTDISELGY
                     DKLTSDEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHATAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            34819..36006
                     /locus_tag="ACOIAP_001737"
     CDS             34819..36006
                     /locus_tag="ACOIAP_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HGZ2638623.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNKDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            36139..37509
                     /gene="hydA"
                     /locus_tag="ACOIAP_001738"
     CDS             36139..37509
                     /gene="hydA"
                     /locus_tag="ACOIAP_001738"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HGZ2638624.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDENIVEIGNNLEINGDKVID
                     ATGRIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKAIGNCYCDYGFHMTITCLDKDTFKHMEKLISDGIVSFKMYMAYEGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLNVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCKESLKTVKMAREKNVDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINCLWEGLASGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISANKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKIKCKVEDVFLRGNHVVQSCNVKEQPIGQYI
                     KRKITK"
     gene            37527..38933
                     /locus_tag="ACOIAP_001739"
     CDS             37527..38933
                     /locus_tag="ACOIAP_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2638625.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHTHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTERD
                     MELAKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTTDEDKALKEAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            39006..39452
                     /locus_tag="ACOIAP_001740"
     CDS             39006..39452
                     /locus_tag="ACOIAP_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HGZ2638626.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKEFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            39491..40285
                     /locus_tag="ACOIAP_001741"
     CDS             39491..40285
                     /locus_tag="ACOIAP_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HGZ2638627.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKNLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMSLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVLRMYNSIGGECDGK"
     gene            40275..42566
                     /locus_tag="ACOIAP_001742"
     CDS             40275..42566
                     /locus_tag="ACOIAP_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HGZ2638628.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPSYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSRALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGKTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVKDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKRKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            42567..43880
                     /locus_tag="ACOIAP_001743"
     CDS             42567..43880
                     /locus_tag="ACOIAP_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2638629.1"
                     /translation="MIAIKSKYLISSADEIYTNYAVVVENDIIKDILPNEEVEIKYKN
                     IEEVIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAVLSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDKFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAHVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWNF"
     gene            43916..45001
                     /locus_tag="ACOIAP_001744"
     CDS             43916..45001
                     /locus_tag="ACOIAP_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGZ2638630.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            45237..46280
                     /locus_tag="ACOIAP_001745"
     CDS             45237..46280
                     /locus_tag="ACOIAP_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638631.1"
                     /translation="MQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEVRQ
                     EMTVMKEDMSEVKQEINIMKEDVSEVRQEINILKEDMLEVKQEINIMKEDMSEVKQEI
                     NIMKEDMSEVRQEMTVMKEDISEVKQEINVLKEDMSEVRQEMTAMKEDMSEVKQEINV
                     LKEDMSEVRQEMAVMKEDMSEVKQEINVLKEDMSEVRQEMTVMKEDMSEVKLEVTVMK
                     EDVSEVKSEVNFMQNKINNINKDMSGIKEEVSIANEKLDGIEIKIDSLESEDKSMKEM
                     QVEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATS
                     KNWSDIVKLKSVK"
BASE COUNT        18051 a         5021 c         8409 g        15034 t
ORIGIN      
        1 tagctatcaa ataaaaattt atgtttataa gaaattctat aaaatatata attaaactta
       61 taaaacattt acattaaatt ctgataaaat atctactata tcaggagtag gcgttttttc
      121 tgtaattata gaactaatat cttctagatg agcaaacttg aaatttccat caaatttaaa
      181 ttttttatct tccataacta taaatacttt tttacttgaa tttattatag ccttctttgt
      241 aagaccatct tcaatttcaa aagttgtaag tgaagagttg aatacatcta ctccgcaact
      301 tcccataaaa gtcttatcaa acttatattt ggatataaac tctatagttg gagtaccgac
      361 aaacccatct aaactgagat ttaataaacc tccagtggaa attatattta aattgtttgg
      421 tcttgaagta actacattta gtatatccaa catatttgta acaagtgtta cctttttatt
      481 actttcagct aacagttttg caagcaatat gttaattgta gagatatcta aaaatatagt
      541 ttctctatct tcaattaaat taaatgcttt ttctgctatt attttctttg ttgggatatt
      601 aatttctttt ctgtcttttg tatcctgatt ctctagtgtt tctctagcta gtacagctcc
      661 tccgtaaatt cttcttattg aagaaatctt ttctatattt tttaaatctt ttcttataca
      721 atcttctgta acattaaatt tagaactgag ctctttgaca gtaactctac cttctttttt
      781 taggatattt aatatggctt gaattctttc ttctgcaaac attttctacc tcttttccaa
      841 atatagtatt atagtaaata ttataagata aaatacaata tatcaactat tttaacatga
      901 aatacaaagt taatttaata taaaaagcat attttttcta actatctatt tacgatttag
      961 taaataaaga aattataaaa ttaagaagaa aaataaaaca ataaaaaaaa ataaaaaaca
     1021 ataagcaaaa tgttgaaaat aatgccaaac caatatataa taagaataaa caaagattaa
     1081 agggggatat tttaatgcaa ctaatcttag atacaggtaa tgtggaggag attaaggagt
     1141 tatgtacttg cttaccaata gatggtgtaa ctacaaatcc aagtattgtt tcaaaagaaa
     1201 aaaagaattt taagcaactt ataaatgaaa ttggtgagat tataggtgag gatatgccta
     1261 tacatgctca ggtattaagt acaaagtatg aagaaatatt agaagaagca ttatatataa
     1321 gtagtttgag aaaaaatata tatgtaaaaa tacctgtaac acaagatggt ttaagagcta
     1381 taaaagacct tcacagaaaa ggtgtaaaaa taactgctac tgcaatattt actgctcatc
     1441 aaggcttttt agctgcaaag gctggagcaa attatattgc accttatgta aataggcttg
     1501 ataatatatc tggtgatgga gtagctatgg tttcagaact tataaaaata atagatactt
     1561 ataaaatgga tacaaaagta cttgcagcca gttttaaaaa tgcacaacaa gttatagaat
     1621 taatgcaaca tggggtgcat agtgctacag taccatatga tatttgtaaa tctatgatga
     1681 atcatccatt aactgattgg agtgtagata agtttataga ggattgggag aatacttttg
     1741 gaaaaggaag taaaacaaat aatatttagt attatggtaa aaaagcagtt ttgttcaatt
     1801 tcacaataac ttgtataaaa agacgaaaat atgaattttc tttttaataa ttccgttatt
     1861 atcttaaatc aattcatatt ttcgtctttt ttaaatttct aatcctataa atctccacca
     1921 agggaatgtt atacatatta ttataaagta ggttaaagga atcaaagtta aaccatactt
     1981 gaaaataacc ttgctattat acagattttc accatgaccc accattattg tagcatgatg
     2041 aaatggtaat atgtattgta tacttactat aatgtagaca aatagacata aagtaacact
     2101 attttccctt agtatatgca aacttccaag cagtggtatt actacagatg atgtagtaac
     2161 agcacttcca agacatatat tcaagattat tgtgagagtt atcaaaaata atatcgaaat
     2221 aatttctgaa gagtttggta taaattttat caaataattt cccattatat ctacaactcc
     2281 ggaatacttt aacactcctc caattgaaaa tgctgctata aaaaaaataa ggaccttcca
     2341 atttatttct tttaaggtgc taaatccaac tatttttctt agtaataaaa gaagtacaca
     2401 aattgacatt ataattaatg tatttatgtt atgtatgaac tgagttaaaa acataaaaaa
     2461 cattattcct aagcataaga atacgtattt ttgttctttg tttagcaaat taagctcttt
     2521 tttaaaatta gaatatgaaa actgaatctt attaacctca agattttcat gagaaacaaa
     2581 ttttattgaa tgtaattctt ttttaaagac aaagataaat aaaaaataag ttataaaaca
     2641 agtaattata gttggaacag acatataaaa agcccattgc ccccaattta tattacaatt
     2701 tccgagttct agtacaacat agtttaggag agtgtctcca tttacaaaaa acattgatgt
     2761 aaaggtagag gctgtaaata tactaaataa aagtatagat tttgaatcct cagttatctg
     2821 ttgttctttt aaaaactcct tgtaaaaagc agatacaaga ataaccctcg gaaatggttg
     2881 tgggataaaa aatattaaaa gtatacctaa aatatatgat aaaagaatca tttttttagg
     2941 ggtatttaca gtatttaaaa ttaacttctc agaaataatt tttgcgacac ctgtttttgt
     3001 aactgcatta gtaattatgt atgcaagaat tattatgtaa aaattttctg taaataaaaa
     3061 ctgtaaaata acctttattg gtgcaatatt aaagataaat gctagaatta caaaaaacaa
     3121 tgcaacaaca gttttttcaa ctgagtctat agcccatatc aagatagtta aaaaagatag
     3181 gcatatagaa aattttatgt tgaaattgta attaagagag aagtagagaa ttatagtagc
     3241 tataacagtt atataaaatt gttttggctt aagaataata cccattttta tattcacctc
     3301 cataatttat tatagcataa tgaaggtgaa tacaatgaag gtgaatacat gtttataaaa
     3361 agtttattta ttgattctat gatttacaat ggctttagtt ttccaacgcc ctttattata
     3421 gtagataact gtgacaataa gacctaaagt ccaaccaaaa ggaataccca tccaaattcc
     3481 atttgttcca aaaaatctag aaagcatata agaagctgga agtcttccaa gccataaaga
     3541 tactattgag cttataaggg caaacataga gtcaccagca cctttcattg cacttgaaag
     3601 cacaaaagaa gtgccaataa ataaaaagaa tggtcctatt ataaataagt aagaagagcc
     3661 aattttaatg acatctttat cagtattgaa tagagcaatt agattttctc taaacagcaa
     3721 aattaaagca ataactataa ctgctaaaac taaggtcatt tttatagatt ctcgaatgcc
     3781 ttttttgact ctttcatttt ctccagcacc tatgttttga gcaacaaaag tagaaacagc
     3841 agaaccaagg ttcataatag gtaagcttat aaaattttca attctaagac cagcaccaaa
     3901 agccgccata gcagatgtac cataactatt aactaaaaat tgaagagcca tatttccaat
     3961 tgaaaataac atttgttgaa ctccacttgg aagtcctaat ctaagcccat ctttaaatat
     4021 tttattatca tatataattc ctttgatttt aaatttaagc acttcatgtt ttttatttaa
     4081 atagattata ctgattataa atgatactgc ctgagcaatt atagtggcaa gtgcaacgcc
     4141 ctcaacaccc atttttagga ctacaataaa agttaagtct aaaactatat ttaggatggt
     4201 ggctattatt agaaaataaa gtggagttat tgaatctcca agtcctctaa gtattgcact
     4261 tactgaatta tatccagcag aaaataatat tccaccaaat attatagtaa gatacaattt
     4321 tgattgagaa aaaacggatt ctggtgtatt cataagccta agcatgggtc caccaaatac
     4381 tattccaaga atacttatta atatagaacc aataaataaa agtatatatg tggtatcaat
     4441 agtagctttt acttttttta aatctcctga cccataaaat tgtgatacta aaatagaaaa
     4501 tccaaggcta acacccataa gtgctgccac caataaaaac attatagggt tagctccaga
     4561 gactgccgcc attgcctctt ttccaataaa tctaccaact attatactgt cagctgtatt
     4621 gtatagttgt tgaaataaac taccaataag catgggcatg gcaaaaaaga atatggattt
     4681 tccctcatga cctgtagtta aatctttcac cttattcctc caaataaaaa aattattaat
     4741 ttattatagt ataatcttaa cataaacttt atatccaaac tataaataaa ttgtatcaaa
     4801 atatcatata tttttttaaa atgtaaagaa tatagttata atttgaattt aataaattaa
     4861 tatttaatat aatcgaatat taatacaaaa tcaacacaat atatacgtat atattgacaa
     4921 aattaattat ataaattaaa ataatattcg taaagaaaaa atcatgtttt atactgtata
     4981 acatataatt ttgacaatat gggtcataag tttctaccgg aataccgtaa atattctgac
     5041 tatgtatact attatttagt taattaaata tttaattaac tgaattatga aggatacggc
     5101 tcagcttatc aactactgtg tcgttttttt gtaaaattta ataggaggtg ttgttatgca
     5161 aacaacaaac agtagtacta tgcagaaact ttttccaatt ttgactaata aaaatgtcga
     5221 catgaagaag gaagtaattg caggagtaac tactttttta actatggctt atataatagc
     5281 tgtaaatcca aatattttat ctgaaacagg aatgcctgca ggtgcacttg ttacaggtac
     5341 ttgtttagca gcagcatttg gatgtatttt aatgggtgta gttgctaatc ttccttttgc
     5401 cttagcatca ggtatgggtc ttaatgcatt ttttgcatat acagtagttt tacaaatggg
     5461 tgttccttgg gaagtagctc ttacagcagt gtttgtagaa ggtattattt ttatagtatt
     5521 atcagtaagt ggagttcgtg aagctgttgt aaatgcgata ccaaaaaata tgaaattagc
     5581 tgttacaggt ggtataggaa tatttattgc acttataggt ctagttaaca gtggaattgt
     5641 tattggagac caagccacac ttatcaaaat gggtagattt acaccagcag taataataac
     5701 ttgtatagga ttaataatta ttgctgtatt agataaaaaa agagttaaag gttctatact
     5761 ttttggaata gtagtgagtt cattacttgc ttgggctttt gcttttatga atccagagca
     5821 tgcacaaaaa ttaggaatat atttacctgg tggattattt aaattcgaaa gtttagcacc
     5881 aatagcaggt aaaatagatt taggatatgt actacatccg aaaaatatag gtggtttttt
     5941 agtagtagtt tgtacatttt tatttgttga tttctttgat acagtaggta cattagttgg
     6001 tgtttgttct aaagcaaata tgttagatga aaaagggaat gttcctaatg taggtagagc
     6061 tttacttaca gatgcagttg caactacagt tggtgcagga cttggagtat ccacagttac
     6121 aacttatgtt gagagttcaa caggagttat tgcaggtgga agaactggat ggacagcaat
     6181 aacagttgga attttattct tagctgcaat gtttttctct cctgtattta tagcaattcc
     6241 atcatgtgct acagcaccag ctttaatata tgttggatac ttaatgcttg gtacagttaa
     6301 agatatagag tttgataata taactgaagg tgttccagct tttgttacta ttgcttgtat
     6361 ggcattaaca tatagtatag gtgatggttt aactttaggt atattaactt atgttttcgt
     6421 aaatatattt tataatatat ttggagctaa aaaggcagaa gacaaaaaac atgtttctat
     6481 agtaatgatt gttctggcaa tattatttat aataaaactt tggctattat aatagatatt
     6541 atttaaaatt ttaatttaat ataaaataaa tagctgtaat ttctcatcaa ttttgatgga
     6601 aaattacagc tatttcgtat ttatttcatt ttattattta ataatatcta ctagctctcc
     6661 attttgtaaa gttttaggtg taattactat attgaactct ttttgcaaat cttttataat
     6721 atccaattct ttttttgtta ttattgagat tgtgttacca tttctatttc ctctagcagt
     6781 tcgaccacat ctatgcagat attcgttttt actttttgga aaatctaagt taaaaacatg
     6841 acttacatcc actatgtcta gtccacgagc agataaatca gttgtaatta aaatctttgc
     6901 tttaccaagt ttaaatttat ttattgcatt ctttctatct tcttttgcca tatttccaaa
     6961 aattcctatt gctttgtaat tatgataatt taattttgat actagaactt ctatattttt
     7021 ttcattattt acaaatacga tagctctctt tggatttgtg gctgttaatg tttttctaag
     7081 aaaagtgaac ttatctctta tttcacctaa caaatatgag tgattgatgt ttggatttat
     7141 ttgtgatttt tcctttgttt ttattatttc aaactctttc ataagtttat cacaaatttt
     7201 tatagtgctg tcagtaagac ttgcagagca tcctataatt tgtctatctc ttaatgttgt
     7261 tcttattatg tcttctatac aagttatatt ttttccattc aatagattgt ccacttcatc
     7321 taagacaata gtttttatat tgtgtgattt taactttttt tgttttatca agtctaaaac
     7381 tcttccacaa gagccaatta ctatgtgtgg ttttactgat tttatatttt ttatttgttt
     7441 ttgtatattt acttctccaa ttaaagctag agaagtaaca gagatttccg catttttagc
     7501 caataattca acttgatttg taatctgcat tactaattca tgcgtaggtg caagtataag
     7561 agcttgtgtt tctctttttg atgtatcaat tttttcaaat ataggtaaaa ggtatgctag
     7621 tgtttttcct gttccagtct gtgaattaat caataaatcc ttattttgaa ttatattccc
     7681 tataacaagt gactgaactt ctgttggaga agttatgtct tgttttttaa gtccatctat
     7741 tagagtggaa cttattttta gttgttcaaa tgtattcata ttttgctcct tatatttaat
     7801 aattatagtc aactattttt tattatacat tgtttaggca aatcgaacta tatattcttt
     7861 tataattatg tgtaatttga aagtaaatat aaattatatt tataccctta taattatgat
     7921 aactttgtat tttataaatt tttaaaataa acaaataaaa gttgtaattg tttgatgttt
     7981 gttatatatt atatataaca aatatcaaaa ctataatatg gagggaaatt atgttaaaag
     8041 taatcaattt atctaaatca tataaaaata aaaaagtagt aaatagtgtc tcatttgatg
     8101 taaatgatgg agagcttttt gggtttatag gacataatgg agcaggtaaa actactacta
     8161 ttaaagcaat tgttggaata catgattttg aaaatggaga ggtactaata aattctaaat
     8221 ctataaaaaa acagcctgtt gaatgtaaaa aggaaatggc atatatacct gataatccag
     8281 atttatacga atcattaact ggtatacaat accttaattt tatagctgac atatttgaag
     8341 ttgccaaaga taaaagagaa gagttaataa aatattattc aaataagttt gaactcaata
     8401 aagcattagg tgatttaata tcttcatatt cgcatggtat gaaacaaaaa ttagctataa
     8461 tttcggcctt gatacatagc cctaaaattt taattcttga tgaacctttt gtaggtcttg
     8521 acccaaaagc ttcctttata ttgaaggaaa ttatgaggga gttttgtgat aaaggtggtt
     8581 gcatattttt ctcaacacac gttttagaag ttgctgaaaa aatttgtgat aagattgcta
     8641 taataaaaga tggaaatata attgcttatg ggactacaga agaagttaaa ggaagtaatt
     8701 cacttgaaag tattttcatg gaattaatag aaaaataaaa tgttttttat acaatatagt
     8761 atctaaagtg aggaatgata aaatatgagc aatctaagta tattaataaa aactaatata
     8821 ataaatgaat ttaaattaaa tgcattaaaa aaatctgatg gtagagaaaa acaaaaaata
     8881 atgggaatga tactttcagc tattatcata acagggttat taatttttta tgtaaccact
     8941 ttaagtcttt ccttagttga tattttaaag caaataaacc agatggaaat gctactgata
     9001 tttggatttg gattgtcaac attaacaact atcgttacat cattatataa aacgtcatca
     9061 tatctttttc aagcaaaaga tttagacatt ttgactagtt tacctataaa agaatctact
     9121 gtactagcaa gtaagatatt aatgttggtg ggagcaaact atttattttc ttcaatctgt
     9181 atgattatac cagcagtggt ttacttttta aattctgatg taagtataac gtatttccct
     9241 tatttgatat tgctattttt agctttacca ttattaccaa tagttgcttc atcaataatt
     9301 tttatgttta taggacagat atcatcaaga ataaaatata aaaatttagt attaattata
     9361 ggtagtatta tattgatgtt gctttatact ctacttatgt caagacttaa ctctatgtca
     9421 gttgaaatgt taaagaatag tgtatctatt tcagagacga ttaggaaaat atatccacct
     9481 atatattatt ttgttgatgc tcttaaaaca ggaagtgtag tttccttttt agcatttata
     9541 gcaatttcaa taataccatt ttttatgttt gtaactttat ttgcaaaaaa atttaaaaat
     9601 ataaatgcta agatgagtga aggatataag tcaaaaactt acaaatttaa gagtcaaaaa
     9661 acttcaagac cttcaaaagc tctattaaaa aaagaattta agagatatac ttcttcattt
     9721 atatattttt taaattcatc tgcaagtttg ttatttctaa tagtaggtgc aattctaata
     9781 ttgttatttg gagcagataa aatgggtgag ttgctgaaat tgaatataga ttttaatttt
     9841 ataaaaatac aattattggg agtattcttc tttataatag taatgaattg tacaacatac
     9901 tgttcaattt ctcttgaagg agaaaattta tggatactga aatcttctcc aatagatgaa
     9961 agagaaatat tctggtcaaa gatattgatg aattttttat tgaatgcacc attatctatt
    10021 ttatgtttaa tattagtatc tataagatta gactttgaaa ttcagtttat tattgtatca
    10081 atttgtttga ttgtaagttt ttcaatgttt gtagcattga tgggattatt atcaaattta
    10141 ctatatccaa accttgattg gaaaaatgaa gtagctgtag taaaaagaag tgcaagtatg
    10201 gtaattacaa tgttagtatc attagcttat gttgttatac ttggaggtat atatacatta
    10261 cttggaattt cgtttttaaa tatatatatt attttggcaa gtatgcttac cttgatatta
    10321 gattttatga tatggagaat tatttctact aaaggagtaa aaatatttaa aaatctatag
    10381 gtgtagttat gtcaaataaa gacttatctt ttttagtctt gcaaataata ggttaagtag
    10441 tatattatgt atagtgatat gaaaaaattt aggagaaaat aaatgagaaa attatccaaa
    10501 aaagaaaaag attttattca atatggattt ttattatttt tgatatgtat tactacttat
    10561 ttagtattaa ctactttaga tataaaaatg atacctaaaa ttataagact agtaaataag
    10621 acttatatat ttcttggaat attgataatt ataatatata tgataattga atctattgta
    10681 actcatttga taataaatgc agttcaaaaa acaaaagtga aattcattgg tattaaaatg
    10741 gctacaatgg gattttatta taacttagtt actccatttg catctgggag tcaaccaatg
    10801 caaatatatg cacttacaaa atatgatgtt agtcttagta aatcagtggc tatagttact
    10861 aataaaacag tagtatttca aagcacagtt accgtatttt gtggaatttt aattttgtta
    10921 aataagtcat tactgataga gcaagtacat tctgtgaaag tcttgataac ttttggaatg
    10981 attatgaatg taagtatgtt gttaggtgga ctactaatag tatttagtcc aaaacaagta
    11041 aaaatgatag cagaagtttt gattaatttt ttatctaaat ttaaaacctt taaattttta
    11101 gattcaaaac gtgatagaat aaatcattat attgatgatt ataattattc tataaaaatg
    11161 tttattaaaa atgtaagaat cttagtttta agtatattac ttactgtttt acaattaatc
    11221 gcatacttca gcatagttta ttgtgtgtat aaagcttcaa atttaagagg agtctcatat
    11281 atacatataa tgacactaca ggtcttttta tatatggcta tatcgccaat tccaacccca
    11341 ggaaatgttg gagctaatga ggttaccttt tttactatgt tttctagtat aattccaaaa
    11401 gaattattgg ggtactccgt gctcttatat agtgggtttg tgtactattt tatattaata
    11461 gtttcaggta tatttacatt tggaacgcat tacacattaa attcttggaa aaaggaaact
    11521 aaagtaaatt ctaatttaga taaggttatt gaaaaattaa attaataaaa taattaggga
    11581 aattctatat ataaatatgg tgttagataa gctatattat attgagatat ttcccttttt
    11641 tgattaaaat tatagaaatt tgaaataata agtaataaac agaacgattg atattgtttt
    11701 gaaaggagaa gttatgaaac aagataaaaa aaatgaaaaa caaagtgaga tttctaagat
    11761 aaaacaaagt aatgataata aacttgaagt agctcaagaa ttacatgtaa gtaaaaatat
    11821 aggaaatatg cttggatata gaatagataa gaaaaaaatg aatagaccaa gttaatgaaa
    11881 atgttgaaaa tagtacattt taaaaaaaat atataatgaa atgttttatt gttaaattta
    11941 aacttatttt aataagggaa aaagtcgaaa aatatctaaa aagatatgga tataaaaaat
    12001 attaatatat atagactata aacttgacaa aatcaacctt ttaatgaata gcaaaaaatg
    12061 gaaaaattat ataagcgtta tttaattatc aaaaatgaaa gctaaattgc atgtgctaaa
    12121 aaaaatgatt gataacattt atttgtgtgc tataattata tagtaaaacg aataagtata
    12181 ttgcataatg tatgcaaatt gggaggagag acagacatgg aagcatctat acacacaatt
    12241 gccagcaata atttattgat aatttttgct attgtaagta taactggaat aatttgtagt
    12301 aaacttagtg aaataataaa agttccagat gtagtgttat atttacttgt aggtatttta
    12361 ataggaccat catttttaaa atttatagat attcgtggat ttcaaataga aaatcaacta
    12421 atacttactt ttggttctgc atttatttta tatttaggtg gaaaagaaat aagtttaaaa
    12481 gtattgagaa atgtgaagat atctgtattc ttattagcta ctttaggagt tgtgatatct
    12541 gcttttataa tgcagcaagt gataggattt acttttggga taagtgcaat gactgcttta
    12601 ttagcaggaa ctataatagc atcaacagac ccagctactc ttgtacctat atttaatcag
    12661 gtaaagataa aggatagagt aaagcaaact gtaataagtg aatcagcttt taatgatgca
    12721 acaggagcta tactaacatc agcagtgttg gctgtaattt tgtcaaataa attttcctta
    12781 ggtgaaaata tttatgaatt ggggacaatg gttattgtcg gagttttagt tggtttaatt
    12841 acaggaatac tgcttttgaa attagttaat gataaacctt atggaatatt taaagatttt
    12901 gcaccaataa tatctgttat ttcagttgta gttgcatatg aattatctac aaaattaggt
    12961 ggaagtggat atatgtcttg ttttattgta ggtataataa ctggtaataa gaaaaacttt
    13021 aaaatttggt taagtcaaaa atcttatgat gcagattttt atgttgctga aactttaggt
    13081 actatttgtc gtatggcaat atttataata ctgggtagcc aagttaattt agctcagtta
    13141 agtaaatatt ttatgccctc tgtaattacg gtattagtat taatgtttat agcaagacca
    13201 ctttgcgttt tagtttgtac acttgtagat agagaagcaa aatggagtaa aagtgaaata
    13261 ttatttatga tgtgggtaag ggaaacaggc gtaataccag cagcactttg tggtattatt
    13321 tcagcaatga aagttcctgg atacgaagta atttcatctg tagtatttat gaccatacta
    13381 attaccttag taatacaagg aagtactaca aaattagtag ctaaaaaact tggattatta
    13441 gaagaagaag ttataaatat aagtgaaaaa gtatcaactt tttaaagttt tgatttaaat
    13501 aatacctatt aatggctatt ttaatattgt ctaatgatga ttattgaaat agtcattttt
    13561 ttatgtataa gcaatttaca gaatttacat attagacata tttattatca aaatttgttg
    13621 aagctatgat ataattagtt gtatttaaaa taagaatagc aaataaggga ggaaatttat
    13681 gtttacggtt atggatattg tacagccaga tacagtagaa gaagcgtact caattttaaa
    13741 taaaagaaaa actaaccaag taattggtgg aagtgctttt ttaagaatgg ggaaaaaaag
    13801 aataggaaca ggaatagaat tatctaactt aaatttagat tatataaaag aagatgaaga
    13861 ttgtgttgag attggttcta tgactacttt tagaacatta gaaacaagtt ccataataaa
    13921 aaataatttt ggaagaataa tagaagattc agtaaaaaat ataataggag ttcagtttag
    13981 aaatgtagta acagttggtg caacagtgtt ttctaaatat ggtttttctg acttgatagt
    14041 agcattactt tcattagata cagaagtaga attatataat attggaagaa ttagtcttga
    14101 agagtttcta aatagggatt atgagaaaga tttacttatt aagatataca taaagaagac
    14161 aaataaaaat gcttcttata aatcacttag aaatgcaaag agtgattatc caatcttaaa
    14221 tgtatctgta tcaaaacata tgaaacaatt taagttatgt gtaggagcaa gacctcagaa
    14281 agctacgatt gcaaaacaag ctagtgaatt tctatctaat aatgaaatca atgaaattaa
    14341 tatagataaa gcagtagaaa tagcatcaga agaattaact tttggttcta acatgagagc
    14401 atctagggat tatagaaaag ctatgagtaa agtactttta aaaagagcta taatggaggt
    14461 tatttaatgt tagtgaagat taatataaat gggaagaaaa aaagtgttga tatagaacca
    14521 gaagaatatc tggttgatac tttaagaaaa gctggtaatt taagtgtaaa aagaggttgt
    14581 gacacaggct gttgtggtct ctgtacagtt ttaattgaca agaaacctac attatcttgt
    14641 gcaacactga cattgagagt tttagataga gaaataacta caattgaagg tttagaaaat
    14701 gaagttaaag aatttagtga agttttggta aaagagggag ctgagcaatg tggtttctgt
    14761 tctcctggtt ttatacttac tgtaattgca atgaaggatg aacttgaaaa tcctacagat
    14821 gaagaaataa agcattatct tacaggaaat ctatgcagat gcacagggta tatgggacag
    14881 ttaagagcta tcaaaactta tctggaggta aaatagagta tgaatatagt tggaaaagga
    14941 atcaagaaaa tagatggaat gagtatcaca acaggaaagc ctgtatatac agatgattta
    15001 tcagcaaaag atgctttggt agtaaagata cttagaagtc ctcacgctta tgcaaaaata
    15061 aaagatatag atacatcaaa ggcagaaatg gttgatggtg ttgaatgtgt tttaacatat
    15121 aaagatgtac caaaatctag atttacactt gctggtcaga catatccaga gccatctcca
    15181 tatgacagat taattcttga agatgttgtg agatatgtag gtgatgaagt agctatagtg
    15241 gcagctgtag atgaaaaaac tgcaattaaa gcaatgaatc ttattaaagt aaagtatgaa
    15301 gtactcacac ctgttttgga ttttgaagag gcaataggga ataacactgt agtacatgat
    15361 gaagatagac attgtaattt tgatataggt atgcaaagag aaaaaaatat agtatcacat
    15421 catgattata caaaaggtga tgtggaaaaa gtattaagta attgtgatat agtgattgaa
    15481 gaaacttatt atactcaagc tcaagcacat gcaatgatgg aaacgtatag agcatataat
    15541 tatttagacc atactggaag attggttgta gtaagttcaa ctcaaatacc atttcatgta
    15601 aaaagacatt tatctcgtgc actagaacta ccatctagta aaattagggt tataaaacct
    15661 agaattggtg gaggatttgg tggtaaacaa actgcatgtg ttgagatttt ttctgcaatt
    15721 gttactttaa aaacagggaa accagctaaa ataatttatg atagaaaaga aacttttaat
    15781 tgttcaacaa gtagacatgc aatgagatta aaagttagac taggtgctac aaatgatggg
    15841 ataataaagg caatagatat aaaagcactt tctgatactg gagcatatgg agagcatgct
    15901 tctacaacta ttggtttggt tggagaaaaa actttaccaa tgtataataa agttgaagca
    15961 acaagattta ttgcagatgt agtatatact aataagatgc cagcaggagc acttagaggg
    16021 tatggagcat cacaagggtg ttttgctgtt gaatcaacta taaatatgct tgctaataaa
    16081 ttaaaaatag acccaacaga tttaaggtta aaaaacgtgg taacagaagg tgaaactaca
    16141 tttgcatatg ggaaaacttt aaatagtgtc gacttaataa aatgtataaa taaaggcaaa
    16201 gaacttattg gatggaatga aaaatatcct tgcaaatatc ttgataatgg aaaagttaga
    16261 agtgtaggta tggcaattac tatgcaaggt tctggtatac aaggtcttga taagtcttca
    16321 gctgaaataa aattgaatga ctgtggagat tatactctta tgataggttc tactgatatg
    16381 ggtacaggaa gtgatacaat tttagctcaa atggctgctg aggttcttga gacgagtatt
    16441 gaaaatataa cagttatatc agctgatact gacttagttc catatgaccc aggttcatat
    16501 gcttcaagta ctacttatgt aacaggtatg gcagtagtta aggcagctca agatttaaga
    16561 gaaaaaataa tttctgctgg agcaaataaa ctaggtgttg ataaggatga agtagaattt
    16621 gatggtataa aattaactag taaaaaaggt agtactttat tatttgatat agcagtggat
    16681 tctacaattg gtccagatac taatcaatta ataggtcttg cttctcatgg tagccctgta
    16741 tctccaccac cttttatagc aggttttgca gaaactgaaa ttgacaaaga aactggtaaa
    16801 gttgatttag taaattatgt agctgtagta gattgcggaa cagttataaa taaaaatcta
    16861 gctaagatac aagttgaagg tggaattgtt caagggattg gaatggcatt atttgaagaa
    16921 gttagataca cagaaaaagg acacatggat acaaatacat ttatgcaata caagattcca
    16981 gctagatgcg atattggaaa tgttaaagta gattttgttg aaacttatga accaactggg
    17041 ccatttggtg ctaaatctgt tggagaagtt gttataaata cacctttacc agcaatacaa
    17101 gaagctgtgt ttaatggaat tggtgtaaga ataaatacac ttcctattac acctgaaaaa
    17161 gtttttatgg caatgaataa ataattattt atgaaatttt agactagttt tacatgttaa
    17221 acaaccagtt atgtcatacc tgttgaaaga tatttaataa gtagttatta taatattgtg
    17281 aattttactt ataaaataca aaattaaata aggggatgat gttttggctg gaaatctaaa
    17341 taatatgaga gcagtaaata attttagagg agataagaac attttagaat gtttagtcag
    17401 ctttgagggt cgttcaataa gtcagagaaa agcaaaggta ttttttaaag aaaaacaaaa
    17461 tcaaatagaa attgattttg tggaagaaga aatttctaaa ttgattgaaa atgttgtttt
    17521 gaatacatca tatcaggaaa tgttatatga tgaaatagaa aaacaactgg aaattgattg
    17581 tataggtact tggatgatat tatctaaatt gaaagatggt agagttcatt gattttaaaa
    17641 taaattatta gagcctaatt ttaaggctct tttttactgc ttttaattaa caacagaaaa
    17701 tctatattta atttacatat aattttaata tcatatattc tatatatata aaattgagtt
    17761 tgtatgtatt atattgtata atataaattg aattagtgaa atagttcgtt aaaataattt
    17821 gtttgtataa aatcattgtt taagtttata gattttgtat aaaataaagt tatgttatta
    17881 atttttttag aagtaaaatt tttactagga gacagatatg agaaaaaata atattaatat
    17941 agcattaacc tcagcaatta cagcaatcta tgcagtttta acattatcat tgggatttat
    18001 aagttatgga ccaatacaat ttagggtagc agagattatg atgcttttgg catttttaga
    18061 taaaggatat atagtaggtc ttacattagg ttgtttttta gcaaatgtaa tagggccata
    18121 tggtgtgcct gatataattt ttggaacatt agccacattt ataagtgcaa gtatgattta
    18181 tattactaga aagttaggta agcaaaataa aagtacttta attatagctt ctttatggcc
    18241 gactatcata aattcgattg tggttgggct aatgttaaat atattctttg gacttccgtt
    18301 aattttatct atgatacagg taggttttgg agagtttgta gtagtaacaa ttgtaggagt
    18361 accatttttt tgttttttaa tgaaaaaata taaaaatatt atcaatatta aattttaaat
    18421 agtgtatagt aatttaattg agagtattat tggtgaaaag aggtgtttat ttgtcaaaaa
    18481 taaaaagatt gactgatgtt tggacatata ttaatgataa gcaaaagttt acaataaaag
    18541 aattatcaga ggaatttaat ctttcagcta aaacaataca acgatattta aaagaattaa
    18601 ataaaatggg acttccaatt caagcagaac aaggtagaaa tggtggttat agggtgctaa
    18661 ataatagcta tatacctcct gttatattta cagaaaaaga agttatggct atgctatttg
    18721 cacttaagtc acttcaggtt tataattata agtcaattga gatagaaatt aattctataa
    18781 tgagaaaagt aagttatgag cgtaagagta gtataaaagt aggtatagaa aatattaaaa
    18841 gatatattgg atttgtagct aataattcta atgatggaga gtttaagagt attaatgtaa
    18901 ctgagttttt tagagcttct tcagagtctc taattttaaa tattaagtat aagtttggta
    18961 atcagatttt ggaaaaaaaa atatgtccta taggtatata tttaaataaa ggagcatggt
    19021 tttcaccagc ctacgattgt aaaattgata aaataatatt agttcatata gataatgtaa
    19081 ttgacataaa aagaacagga gaaagtaaaa aaatacatat aaacttggaa gagtggctag
    19141 atgaagtata taacaattta tatgaaaata ggtcaaccac taaaaaaatt ggtgaaacga
    19201 tttatctaaa tgtattatta actaaagaag gtgtttctaa aataaaggac agttcttata
    19261 atttagatat ggaactaaat gaggatggta gtggaacaat tagtacattt ataagggttg
    19321 aagatgtaga ttactatgct tctattttat ttttaattgg aaataatgct aaagttatag
    19381 aaccaaaatt tctgaataag ctactttatg acaaggccaa tgagttaaga tatttttatg
    19441 aagaaaatat ggtataatat ttagaaatgt tgaaattaaa taattattaa ggagatatac
    19501 attataatgg aaaattttaa taagaatgct aaaataattg gtattggagc tgaaggtatc
    19561 aatataataa atgaaataga agaaaaaata aaagccaata tggatataga aaaaataaac
    19621 ataaatcaag agattgaaaa agaatacgtt agaagtcttc tagatggtgt agatatatta
    19681 tttttaatat attcatctga agataaacat attaaagaga ttataaaagc tatttcatat
    19741 atgtcaaatg agagaagagt tctatctata ggaatggatt gttcagagaa agaaaataaa
    19801 gaagctttag agcttggaag agaatttaaa atcaataacg atagtatatt taaatttgtt
    19861 aatttaatga atatcatggt agagtctatt tctgattctt gcatgataaa tatagatatt
    19921 actgatttaa aagaagctat tgtaggagat aaaggaatta agtattcttt tgaagagttt
    19981 gaagatacaa aggaatatag cgagatggct gacattttat ttgacagaat ggaatatatt
    20041 ggtgaggaat ttataagcaa gaaaggaatt gtatttgttg aaggaagctc ggaattttct
    20101 ataatggaac ttaatgattt aataaataat attcagagaa agatagaaga aagttatgaa
    20161 gtaatatttt ctttatatat gaaggaaaat ctagatggaa atattagaat aggtttattg
    20221 tataattagt atattttaga tattaaggag agtgtatatg tctgaaaata taagagttac
    20281 agagtactgg ctaatggaag aattttttta tcaggaaaca gacacaccac agatttttag
    20341 agaagaaagt ataattgcac ttggatttga tataaaaata aatttaaaaa aagtatttgg
    20401 tatgggaaaa aaatcagaaa agtatattaa tgagaattgt aatgataaag attttataaa
    20461 aagatttgtg tcaattaaaa aaggagatta ttttttatat aaggcatatc aaaatataga
    20521 agaaaaagtt aaatgtaatg tgtctattgg catggttgaa gaagattttg aaaatggata
    20581 tgaattaagt catattttag ggcatacact accagtaaaa tggatgtata attttgatac
    20641 agtttcaaat tgtaaagtat atacaagtga attttataaa ttaaataata atgatattag
    20701 ctcatattta gaaattatta attcacaaga taagaaatca ttgagaaaaa gaatagaaga
    20761 aagtgaaaat aataaatggt atttaaaaaa ctattattat aaaaatgtag ataaatgtgt
    20821 aaatgatgaa gaactattta ttcagcctac taatctagaa cagttagaaa atataaaaaa
    20881 tataaaaaca gatgattaca ttttattgta taatagcgag aaagtaatct gtgaaaatga
    20941 ccatacaatg aagagtctat ttggtgtatg tcaagtcatg gaaggattcg ataaagagaa
    21001 agtaagtact ttggaggatg gatatttttt ccctgttaga tggatagagt atgaaaagga
    21061 aaatatagat ggaaatgcat gggttatatt tgaaaataat agcatggttg aaaagtatgt
    21121 aaaaagattt actaataaaa taccattaaa tactatactt tatggaccac caggaactgg
    21181 taaaacatac aatacaaaac agatggttta taatctagta aataaaacta gtttaagaaa
    21241 caggtactat acaggttact tagattataa aaataatgta gaattttgca catttcatca
    21301 atcatatgga tatgaggaat ttatagaggg tcttaagtct gatggagaag gcaactttaa
    21361 accagaagat ggaatattaa aggatatatc tatagaagca tgttatgatg cattgaaatt
    21421 tgaaaaaaag atgagttttg agttagaaaa agatagcttg actttagaag ctataaaaaa
    21481 gagaaaaaag aagttagtat tagaaaatat agaatatagt gatagtttta attttgaaga
    21541 atcagaaaat tatgttttaa taatagatga aattaataga gggaatgtgt ctaaaatatt
    21601 tggtgaacta ataacattat tggaagatga taaaagactt actaaatcaa atcagactat
    21661 tgtcaaacta ccatattcaa aagaaaaatt ttttctacct cccaatttgt atatagttgg
    21721 aaccatgaac acatcagata aatcaatagc acttttagat atagctttaa gaagaaggtt
    21781 taattttgaa gaaattatgc caaattatga tttattgtct attatagatg gcatagatat
    21841 tagaaaaatg ctatatacaa tcaataaaag gatagagttt ttgtatgata gagaccatgt
    21901 tattggacaa gcctatctac ttgctgtgga aaatattaat gatatagtag tagtatttag
    21961 aagtaaaata ataccacttc ttcaagagta tttttattat gattcagaaa aagttggttt
    22021 gattttagga ggaattggaa gaaatgaaaa agataaatac attgtttata aagaagaact
    22081 tatagcttct gagttattta aaaataataa tgcctcaata atggagagta aagttaacta
    22141 ttgtataaaa caaaacatat ctagtgagga gttaaaaaat atatatgagt aaaaatatat
    22201 atgttaagga aacttatgaa tggataagag taggtaatgg tgaaaatgag cttacagaaa
    22261 ttgaatatga aaaattgctt aaatatctag agaacaataa tgatgtatta aaaagtaata
    22321 taatagatat taaatacaaa aaacttagat ttataaacta tgtaggtatt atatgttttg
    22381 aaaatataat acttgaaata cttcctaagt tgtcattaag tgataatctt gtaaaagata
    22441 gagagatact attacagatg ctttccatat gtaataaaat tccaattata atgaatgaaa
    22501 aaataagatt aagtttaaaa aattataatc tcctaaattt ttttattatg tatttcattg
    22561 agagtatgca aatacagatg aagaaaggta tttattttga atatataaat aaaatagaga
    22621 acttaaatgt tataaggggt aaaatattat taagtacata tgcaaaagaa aaatgtattt
    22681 ctccaatgaa aataagatgt gaatatgatg aatatagtga aaataatttc ttgaatcaag
    22741 ttcttaaaaa agcatgtata tctattttat gtagaataaa tgacaattca attcaaggaa
    22801 agattaaaaa aattttaaac tattttcaaa atgtagattt aatttatata gatagaaaaa
    22861 aactattaga ttataaattt tgtaaaaaca atgatagatt tagagattgt tatttactag
    22921 ctagacttct acttttaaat ttgtctatgg ataatagtca agataatgaa gaggcatttt
    22981 ctatattatt tgaaataaat actttgtatg aagaatatat aggaatttta atcaaaagta
    23041 tatgggataa ttcatttaga gaaacatata tacaagataa gagtaaattt cttttgaaaa
    23101 atgaacaaac aggtaagaaa aactttaatt taagaccaga tatagtttta tatgatttga
    23161 aaagtgaata tgaaattata attgatacta aatggaaagc tattgaagta gattcaaatg
    23221 ttttttatag gtcaagtgat atataccaga tgtatgcata tataacaaca tatgaaaatg
    23281 caaaaagatg tatattatta tatccttgta ttcaaaaaga taaaaattat agttcttgga
    23341 aattatcaga atcatttaag ggtaagttta tagaagcaaa aactgtgaga ttagatgata
    23401 taaaaaacac aaaaaatgat ttaaaaaaga taatttttaa ttataaattt taaaaataag
    23461 aattttaaaa tttataaaag taattttata taggtataaa atttctgagt agtataaaaa
    23521 atttaataga gacttagatt aaaaattatt tttatgtaaa atatggcatt ttaattgctt
    23581 atttaataga ggattcttgt aaagttaaga aagtatatct atcaaattaa aactaagtgg
    23641 atatactttt tattaagttt tgttttaaaa taatattatt aaattatagc tatgcttttc
    23701 tgttatgata taattaaata gataatgtga atgattatta tatagaatac ttatttggag
    23761 ttgatatttt atggacaaac acagtgattc agtaatgtat ggtggaatgg aagtatacaa
    23821 tatttgggga acaacaacag tagactccat aattggagag tctgatgtaa tgcgtgctct
    23881 taagaataga atttgcaaaa ttggaaatag tgattctact gtagctataa ctggagaaag
    23941 tggcactggg aaagaactaa tagcaagagc cattcatctc gcaggaaaca gagggaataa
    24001 aacattcgtt gctataaact gtgctgctat accagaacct ttactagaaa gtgaactttt
    24061 tggatataca aaaggagctt ttagtggagc agattcaaaa ggtaaaattg gtaagtttga
    24121 attggccaat ggaggggttg tatttttaga tgagatagga gatatgccaa ttcaactaca
    24181 atcaaagtta ttgagggtat tacaggaaaa gaagtttgct agaataggtt caaatgaact
    24241 aattgatata gatgttagaa tcatatcagc tactaataga gatttatttg agttggttaa
    24301 ggaaaataaa tttagagaag acttatacta tagattgaat gtaatacctt tagaggtgcc
    24361 tccacttaga gaaagaggag acgatataca aatattaata aacaatttta tagacaaata
    24421 ttcgagaaag atgaagaaaa acgtgtacca tatagaacca gatgtggaac aaatgctgct
    24481 taagtatcct tggccaggga atattagaga gttggagaat actatagaac ttgccttaaa
    24541 tcttcttgag gaagatggaa taatacataa aggtataata aacagaaaga taattgaata
    24601 ttttaagcta aataatataa atataaagct acttgaggaa aatgactatg agataagtat
    24661 ggaacaagac atacttacgc ttgaagaatt tgaaagagcc tatataaaga aagtgttaaa
    24721 gttttacgga aatgatacta agtctaaaaa actggctgct aaaaaacttg gaatatcact
    24781 agctacattg tacagaaaaa tagatgtata ataattagac tttttattct caattctaaa
    24841 atttgaaatt ataaaattga taaaaaacac ttggaaaact attttctaag tgtttttttg
    24901 tgcaatagta ttttattatc caaaaataaa aaaaatttga aagaatttaa aaaaagaaat
    24961 gctttaataa attatcaaat actaacaaat ataataaaaa ttatatatgt aaaacaatta
    25021 tgttaaaaaa ttggcattat aattgcttca tattaagttg agatgacaaa ataaaaaaag
    25081 aaaggatgtt gtgtgagata ataataactg tcattaaaaa atagttggga gtgataacct
    25141 tgagtaaata tcaaaaaaat gtttctatgt ttgatattga tggaaggcca ccaattttaa
    25201 agtgtttacc actatcaatg caacatatat tggcaatgat agttggaact gttacagtac
    25261 ctatagtcgt aggaggagct gtgggtgtta gccctacaca aataacactt ttagtgcaat
    25321 atgcattaat aatagctggt atatcaacac ttatacaact atatccaata ggaaatattg
    25381 gttcaagatt gcctataatt tttggagttg gttttactta tgtaccaaca cttgtagcag
    25441 tcggaggaaa ttatggatta gcaagcattt tgggtgcgca attaataggg ggagtggcta
    25501 cagtattaat agggatattt ataaaaaaga taagaaaatt ttttccgaat atagttgcag
    25561 gaacagttgt ttttacaatt ggattatctt tgtatcctat agcaataaat tatatggcag
    25621 gtggtgtaaa tagtcctaca tatgcttcta tgcaaaactg gtcagtagcg gctataacac
    25681 tagtggtagt tataggtctt agtcaatttg caaaagggta tgcaaaattg gcggcaatat
    25741 ttttgggaat tatagttgga tattgtgtat ctttagtttt gggtataata aattttgacc
    25801 ctattagaga ggcaacttgg tttgcgatac ctaaaccact tgaatttggg atggaatttg
    25861 atatgcctgt aataatttca gtagtaattg taagtataat caacgctgtt caagcaattg
    25921 gagatttatc agctactaca atgggaggta tggataggaa tatcacagac aaggaattat
    25981 caagtggagt aataggaagt ggaatttgta ctatgatagg agctttgttt ggaggtttgc
    26041 caccatcatc atatagccaa aatgtgggga tggtagctat gaacaaagta attagtagat
    26101 ttgtgcttgg aatagctggt atatttatgt tattgtcggg gtttgtgcct aaatttggtg
    26161 cattaatgac taccatacca tattctgttt tgggaggagc tacaatatct atatttagta
    26221 tgataacaat gacaggtata aagttaatta ttacagaaga gttgtcatca agaaatatta
    26281 ccattgttgg tttggcaatt gctttaggca tgggaataac atcagtccca gcagcccaag
    26341 aagcgtttcc ttcatttgta aagttagtat ttggagaatc tccaatagta attgcgacat
    26401 tggttgcatt cgttttaaat ctaataatac caaataaaag tctagaggat gaagctaaag
    26461 aaagagctgt tatggaagag actaattaag atataatagt ttgaaaggat tgttcaaatt
    26521 atttagtatg agattgttag attatttttg atagctattc attttaataa aaaatttaac
    26581 aaataaatat ataccaaata attaatattt atttaagttg aaaatcgggg aggtaatatt
    26641 tagaaatttg ttaatttttt ataaaaatag ctcagtttag ctgtgtttat cggttgagca
    26701 ataaattcat ggtcataaaa atatttatag aaaataatta taaaaatatt tagtcaagat
    26761 atttatgtat gggaggattt attttatgaa aacacgtaat acttcaaaat atgatgtcga
    26821 tgggatacca ccactaaagg aatcaatacc tttagcctta caacatctgt tagcaatgat
    26881 agtaggaaat atggtacctg cgatattaat agcaaacgtg gtaggactta accaggggca
    26941 agcaacaatg ttgattcagg gttctatgtt agcagcaggt ttggcaacgt ttttacaatt
    27001 atatccaata cctttattta aaggctttaa attaggttca agattacctg taatgatggg
    27061 aatgagttat gtatttttag gagcctgtct ttcagtagcc gctaaagatg gtttagctgc
    27121 tctatttgga gcacagattg ctgctggggt aattgtattc tttgtaggtt ttggagttaa
    27181 gaaaattaga catatattca ctccaatagt ttctggaact ataatagcat gtatgggact
    27241 tggattattt gcaacagcta taaagaattt agctggagga gaaggtgcac aaacatttgg
    27301 aagcccaata aactttacag taggagttat agttgctttt gtaataataa tgataaataa
    27361 atatggtaaa ggtttagtaa aaaattcttc aatattaata ggaatattag taggttatgc
    27421 tatatcttta gttttaggat tggttgattt ctcagccgtt cagggagcag ctatagtatc
    27481 attaccaaca ccagcagctt ttggattaga atttagacca gagttaatag taatgtttac
    27541 tattatttac ataataggta tagctgatat gatgggtgcc tgtacaatag ctacagtagg
    27601 agcaatggat agagaggtaa ctgatgaaga attagcatca gttgttttag gaaactctgt
    27661 aacttctata atttcatcac tatttgcagc tcttccaact ggagtattta gccaaaatac
    27721 agtaattgta tctatgaaca aagttacaag tagatttgta atagcactag gggcacttgt
    27781 attattacta gcgggaatat ctccagcatt gggcgcaata atgacaacta taccatcttg
    27841 tgttgttggt ggagcaactt tagtagtttt ctcatcaata gcaatgtctg gtttctctat
    27901 tatgagcatg gatggattta ctgaagaaaa caatcttata gcaggtgtat ctatagcaac
    27961 aagtatgggt cttacgactg ctccacaagt tttagaccaa ttcccagaaa caattggaac
    28021 tgtccttgga gggtcaagta tagtttctgg agcaataata gctatattac ttcagacact
    28081 atttaaatta aagtcacgca aaagtgctga aaacgttact tcaaatcttg aggaaaatat
    28141 tggataaatg tattagatat aatatgagaa aaccatatgg taaaatgttg taacgaaagt
    28201 attcaaaggg ggatttaaga tgattgatat actaataaaa aatgcaataa ttgttacagt
    28261 taataaagac agagatgtta tatttgatgg agcaatagct attcaaggtg acagaatctt
    28321 ggatatagga aatacagttg acattgaacc taagtatctt gatgctaaaa gagttataga
    28381 tgctaatgga aaagtaatat tccctggctt tataaatact cataatcact tgttccaagt
    28441 attattaaaa ggtctaggcg atgatatggc acttcatgag tggttaaata caatgatgtt
    28501 tccatcagca aaattcttaa cagaacaaga tacttatgat gctgcaatgc ttggatgtat
    28561 ggaaggttta aaaagtggta taactacaat ggttgattat atgcatactc acaatagacc
    28621 aggacttaca gatggaatag taaaagcata taaagattta ggtataagag gggttgtagg
    28681 tagaggttgt atagatttag gtattcacaa agagcttata gaagatgtgg aaacggttga
    28741 aaaagatttg agaagagtat ttgaaaaata tcataattca gaaaatggaa gaataaaaat
    28801 ctgtgtagct ccttcttcaa tgtgggctat atctgaagaa atgggtaaga tgctttggaa
    28861 tatagttaaa gaatatgatt catattttac agttcatata tctgaaacag aatttgcaag
    28921 aacagcaaca aaggatatac atggagaaat agatataaaa ttacttgaaa aatggggcat
    28981 agtaggtcca gaagtcgtag cagtacattg tgtgtgcata actgatgaag atatggaaat
    29041 gcttaaaaag tatgatataa aagtttctca caatgtagca agtaatatgt atcttgcttc
    29101 tggtgttgct cctgttccag aaatgttaaa aaaaggtata aatgtgagtt taggtcttga
    29161 tggtgcagca agtaataatg cacaggacat gatagagctt atgaaactaa cagctttaca
    29221 acacaaagta aataattgtg accctctagc aatttctgca gagaaagttc ttgaaatggc
    29281 tacaatcgag ggagcacgaa ctcttagaat ggaagatgaa ataggctctt tagagattgg
    29341 gaaaaaagct gacttagtaa tatttaactc aatgctttct ccaaaatcaa tacctcttca
    29401 caatcctgta tcaactttgg tatactcagc tagtatgcac aatgtagaga gcgttttagt
    29461 tgatggaaat ataatacttg aaaatggaaa agtaactaca attgaaagtg aagaacaagt
    29521 gttgcttaat gcacaacatg cagcagaaga attatgtaag agagctaatg taactaatag
    29581 aatggaagga cataagtgga atagcttata ctaatattaa aataagattg taataatatt
    29641 ctattacaac attagtttat ctgtaggagg agaaaatgga aaagataaaa ttaaatatta
    29701 atgattacat gtatgaaata gaagttgaaa agaatgaaac tcttttgcat gtacttcgtg
    29761 aaaaattaaa tctaactgga gcgaaacaag gttgtaatag tggcagttgt ggagcatgta
    29821 aagttttgat agatggagtt gacatgaaat cttgtaaact tcttgcaaga aactgcgaag
    29881 gtaaagttat atacactata gaaagttttg ctaatggaga aaatcttcat ccaatacaag
    29941 aagcttttat agaagttgga gctgtacaat gtggatattg tactcctggt atgattataa
    30001 caacacaagc tcttttaaat agaaatgcat ctcctaatga agatgaaatt agagaagcct
    30061 ttaaagagaa tctctgtaga tgtacaggat atgtaaaaat tatagaagct gtaaaattat
    30121 ctgcagctag attagggggt agataattat ggaaaaagta ataggaaaat cataccctct
    30181 aaaagatgca gctttaaaag ttactggtca aatgaagtat gtggctgata tgaaaccaca
    30241 aaatgtactt tatgctaaaa tgcttttaag ccctgtagca catgcaaaaa taaaaagtat
    30301 agatacaagt gaagctgaga aagtagtagg tgttagagct atagctactt atctaaatac
    30361 atcacaaaga aaatacaatg gtgcattaag attttatgag cacaatatac ctgaaaatga
    30421 agttattttt tcagatacag ttagatttgt tggtgaccgc gttgcagcag tagccgcaga
    30481 gactccagaa atagcagaga aagctataaa acttataaaa gttgaatatg aagagttacc
    30541 agctgtattt actatacaag aggcaataaa agaagatgct atctgcatac atggagattc
    30601 aaatatagtt tctcaaaata acataaatgg gggtgatgta gaaaaaggct tcaaggaatg
    30661 tgactatata tttgaagatg aatactctac tccagcaata catcatagtg caatagagac
    30721 tcatagtgta attgcacact atgattataa tgataaatta actgtacata caccttgcca
    30781 aaatacattt ggatttagaa taatactgtc tcaaattttt gggatgtcat taaataaagt
    30841 aagagttata agacctgcta ttggaggttc atttggagga aaattagaac ttacaattga
    30901 gccagtagca gccgcattat caaaaatgac aagaagacca gttaaaatgg ttcttacaag
    30961 aaaggaatct atgatatcaa caagaactcg tcatgggtcc tttgtaaaat taaaaactgg
    31021 tgtaaataaa gatggcgaag taatagcaca agatataaaa atatatacaa atacaggcgc
    31081 atatgcatca agtgctttaa atgtcatagg agcacttagt cataaagtat ttaaagttta
    31141 taaaatacca aatataaagt ttactggaat gcctgtatat actaatacac caatagcagg
    31201 agctatgaga ggttatgggt cacctcaaat atttatggct caacaggctc aatttgcgaa
    31261 aatagccaag gaactaggta tggatttagt cgattttcaa aataaaaatg cagtagagcc
    31321 agatgatgtc gatataatct tccacggttc tcttggaaat cctagagtat tggattgtat
    31381 agagcaaggt aagaggatgt ttaagtggga tgaaaagaaa aaacttccaa aagaagaagg
    31441 taaatattta agaggtatag gtatggcaat aggtgcacat ggtaatggag tttttggtgc
    31501 acatagagat gttgttacat tgactcttaa attaaatgaa gatggtacat tgacactaat
    31561 aacaggagca catgatatgg gtaatggtgt tgtaactatg caaacaatga tggtagctga
    31621 aattttagga ataacacctg ataaagttga tacatttgaa actgatacgg atgcatgtac
    31681 attcaacctt ggtgattatg ctagtagagg ggtatttgta gaaggtggag gagctaaaaa
    31741 gactgcagaa aaattgaaag tccttatatt agaagaagca gaaaaattac ttgaaacatc
    31801 aaaagaagat ttatatctag acaatggata cgtaattagt aaacttaatg aaaatataaa
    31861 agcatcactt tctgatgtcg cagtatatag tcaaagtaaa tcattaagag agttaactgt
    31921 tgttgaagat tattcttcac caactggact tacttcttat ggtgtacatt ttgctgaagt
    31981 tttagtagat aaagaaacta aagatataaa agtagttgat tttgtagctg tacatgatgt
    32041 tggtagagtt ataaatcctc taaatttaga aggtcaatta gaaggcggga ttcatatggg
    32101 tctaggatac gcattgagtg aggagttggc atttgatgaa caaggtagac ctaaagctac
    32161 tgattttaaa acatataaat tatttagaac tgtagatatg ccaaaatgtc aagttgcatt
    32221 tgtgaatagt tatgaaaaag ctgggccttt tggtggtaag agtattggag aatgtgctgt
    32281 tgtaccagtt gcaccagctg ttgcaaatgc agtatataat gcaacggatg tagaaataca
    32341 ttcattgcca ataaaattaa aatagtagaa aaagcataaa taacaattta ttgtatttgt
    32401 aaatagataa taaaaataga tttatttggt gaggagatat tattatggca aagatattag
    32461 ggatttgtgg aagtccacgt aaaggagcaa cagaatatgc agtgctagaa gctttgaaag
    32521 aagcagaaac tataccaggt atagaaactg agtattggtc agttagaggg aaaaaaataa
    32581 gtccttgtgt acattgtgat gcatgtataa gaaaagaaac tatgtgtatt ataaaagatg
    32641 atatccaaga attagagcaa aaaatattgg aggcagatgg aattatagta ggttctccag
    32701 tttatgatat gaatataact gctcaactta cagcagtgtt taatagactt cgtccaatgt
    32761 atttagttca tccaggaaaa cttcaaaata aggttggagc agctataact actggtggaa
    32821 ctagatacgg tggtcaagaa ttgacaaaac ttcctataat aaatttcttc ctaatgcatg
    32881 aaatgttagt atctggaggt ttaggtggat gctatatagg tggtacaata tggagtaaag
    32941 atggaaaagc aaaaggtgcc caagaggatg agacaggtat ggacacagta aaaagacttg
    33001 gtaaaggtgc tgcagaggca gttatggttt ctaagtttgg tcttgaaaaa tggaatgtcg
    33061 taaaagaaga attagatgtt aaaaaagatg aaaaatcacc tcttagagac cattaaatat
    33121 ttattatatt attaaatata tacaaatagt gatgtaatag attattgcat cactatttta
    33181 tgttttaatt tagattttat aaattttata ttaaaaaata tagaaacaaa gtgttttgag
    33241 atttgttttt aaattttaaa aatgagaatt aaaaagtgag aagatagaaa aggtttttta
    33301 gttattaaat tctatataca ttgtatgaac taaagataga aaagaaaaaa taataaaagc
    33361 attgcaattt ctatactaaa gagtcatgga aaaatattta gtatatattt agtgttggca
    33421 tgttaattgc ttatatatta aagtataaaa atttaacaat aatttggagg tattttagat
    33481 gttaaaagaa attaaatgga aagtaaataa tttgccaaag ggtgataagg aaaattgtat
    33541 caaattttta aatgaagaag aaataactaa ggttagaaac tttcacaaaa gctttcctca
    33601 atataaagaa actccattag caaacctaga aggtttagca aaaaaattag gtgttgcagg
    33661 agtatatgta aaagatgaat cttatagatt tggattaaac gcatttaaag tattaggtgg
    33721 ctcttattct atgggtaaat atttagctca aagattagat acagatatat ctgagttagg
    33781 gtatgacaaa ttaacttcag atgaaataaa agaaaagtta ggagaaataa ctttctttac
    33841 agctacagat ggaaatcatg gtagaggagt tgcttggaca gctaataaat taggtcaaaa
    33901 atctgttgta ttaatgccaa aaggttcttc tgaatttaga ttaaataaaa tcaaaggaga
    33961 aggtgcagat gctagtataa cagacttaaa ctatgatgat gcagtaagat tagctaatga
    34021 ttatgcagaa gctgatgacc atggagtaat ggttcaagat acagcatggg acggatatga
    34081 agaaatacca gcatggataa tgcaaggata tggaactatg gctcaagaag ctatagaaca
    34141 attaaaagaa tatggagtag atagaccaac acacgtattt gttcaagcag gagttggttc
    34201 acttgctggt gcagttcaag ggtatgttgc ttcaatatat gatgaatgcc caataacagt
    34261 agtagtagag gctgatgagg ctgattgtta ctataaatca gcagaagctg gagatggaaa
    34321 accaagattt gttggaggag atatgccaac tataatggca gggcttgctt gtggagagcc
    34381 aaatactata ggatttgaag tgttaaaaaa tcatgcaaca gcatttgttt cagcaccaga
    34441 ttgggtatct gctaaaggta tgagaacatt aggtaatcct ttaaatggtg atgaaaaggt
    34501 aatttctgga gaatctggag cagttacaac tggtctttta gtagcagcta tggaaagaga
    34561 agatttagca gatttaagaa aagatttaaa attagatgaa aattcaagaa tacttttaat
    34621 aagcacagaa ggagatactg accctgacaa atatagaagt atagtttggg atggagaata
    34681 tccaagtata taaggaatta ctaaaatgca attattagat attggtttac atatttagaa
    34741 gatatataag ttctaaattt tagaaaatat atagtatata aaatacatac attataaaaa
    34801 atctaggggg ataatgaaat gttaaacgaa caaagaaaac aagaagtaac tgaaatatgc
    34861 caaaaattaa ttcaaaatcc tagttcttct ggaaatgaag aaggtgttgt aaaagcaata
    34921 gaagagtctt ttgaaaaatt aggttttgat agctggtcaa gagatagata tggaaatata
    34981 gtaggatgta taaaaggtaa caagccaggt aagaaaatat tatttgatgg acatatagat
    35041 acagttccag ttccagatgc aagtaaatgg agtgttcctc cttttgaagg aaaaatagtt
    35101 gatggaaaga tatatggtag aggaacttct gatatgaaag gtcaatatac tgcaatgatg
    35161 tctgctgtag cttattttgc taaagatact aataaagatt ttgctggaga actatatgta
    35221 gcaggtgttg ttcatgaaga aatattcgaa ggagtttcag ctagagagat aagtaaagct
    35281 gttcaacctg actatgttgt aataggtgaa tcttcagagt taaacttaaa gattggtcaa
    35341 agaggtagag gagaaatagt agtagagact tttggtaaac cagctcactc tgctaatcca
    35401 gaaaaaggtg taaatgcagt ttataaaatg gctaatgtaa tccagaagat acaacagtta
    35461 gtacctccaa ctcatccagt tttaggtgat ggaatactag ttttaacaga tataaaatct
    35521 tctccatatc caggagcttc agtagtgcca gattattgca aagctacttt tgacagaaga
    35581 ttattagttg gagaaacaag agaaggagta ttagctccaa tacaagcttt attagatgaa
    35641 atgatgaaag aagacccaga attaaatgca aaagtttctt atgcagttga aaaagctgac
    35701 tgctatacag gaaatactat agaaagtgaa agattcttcc caggttggtt atatgacgaa
    35761 gaagatgagt ttgttcaagc agcgtataag ggactaaaag aagctggaat agattcagaa
    35821 ataactcaat actcattctg tacaaatgga agtcactatg caggtgaggc tggaataaaa
    35881 actataggat ttggtccttc taaggaaaat cttgctcata caatagatga gtatatagag
    35941 caagagcaat tatttatagg aacagaaggt tactatggaa tattaaaatc tgtatacgga
    36001 aaataatgtt tagttcacaa taaattattt aaatatagtc tagaggtgct gaatatagca
    36061 cctttagaaa atacaatttt aaataaaatt ttacgatacc tagaaaatac tttaaagctt
    36121 aaaagttagg aggtatatat gggaacaata ctaagaggtg gaactataat tacctctgat
    36181 aagacttata taagtgattt aaggatagaa gatgaaaata tagttgaaat aggaaataac
    36241 ctagaaataa atggtgataa ggttattgat gctacaggta gaattgtaat tcctggtgga
    36301 atagacacac atactcattt tgatatgaat gcaggttcta ttacaactgc agataatttt
    36361 gaaacaggaa caagggcagc tatagctgga ggaactacta caatactaga ttttgcagaa
    36421 gccaacgagg gggaaaattt actacaaggt gtagaagcat atcataaaaa agcaattgga
    36481 aattgttatt gtgattatgg ttttcatatg acaattacat gtttagataa agatacattt
    36541 aaacatatgg aaaagcttat ttcagatgga atagtatctt ttaagatgta tatggcatat
    36601 gagggcatga aagtagatga tggaacaata tacagagttt taaagaaagc aagagattta
    36661 ggctgtatag ttggatttca ttgtgaaaat ggggatttac taaatgtatt gatagaagaa
    36721 aatatacaaa atggtaatct agagccaaaa tatcatccac ttacaagacc taacatagtt
    36781 gagaaagaat ctgtttcaag gcttgctgat ataactaaat tatctaattc aaaatcctat
    36841 gtagtccact taagttgtaa ggagtcactt aaaactgtaa aaatggctag agaaaaaaat
    36901 gtagatatga tagtagaaac atgcccacaa tacctattat tagaagacaa tttatataat
    36961 aaggataaat ttgagggtgc taagtatgta atgtctcctc ctttgagaaa aaaagaagac
    37021 ataaattgcc tttgggaagg gttagcgagt ggagatattc aaacagttgg cacagaccat
    37081 tgttcattta attttaaggg acaaaaagac ttgggaatag atgattttag taagatacca
    37141 aatggagcac ctggtgttga gcataggtta gcccttttat atacatatgg agtcttagag
    37201 aatagaataa gtgcaaataa atttgtggaa gttacttcta cgaacgccgc aaaaatattt
    37261 ggaatgtatc ctaaaaaagg cgagatagct gtaggaagtg atgcagatat agtcatttta
    37321 aatattaata aagaagaaac aattagttat aaaactcaaa aacaaaatgt agattatact
    37381 ccatatgaag ggtttaaaat taaatgtaaa gttgaagatg tatttttgag aggaaatcat
    37441 gtagtgcaaa gttgtaatgt taaagaacag ccaataggac aatatattaa aagaaaaatt
    37501 actaaataat gcggggggaa ataagaatga tggatatact tattaagaat gccataatag
    37561 taactgtaaa taaagagaga gaagttattt ttgatggggc attggtagta aaagataaca
    37621 agattgctga tattggaaat tctaaagaga tagaaagtaa atatacggat gtaaaaaaaa
    37681 ttatagatgc taaaggtaaa gttttattcc caggttttat aaatacacat actcatttat
    37741 tccaaacttt attaaaagga ttgggcgatg atatggtact taaagattgg ctagaaacta
    37801 tgacatttcc agcagctaac tatttagaac caaaagatac ttatgatgct gcaatgcttg
    37861 gatgtattga aggtcttaga agtggtataa caacaatggt tgactatatg tatcctcata
    37921 gtaagccagg tctttgtgat ggaataatag atgcttataa agaattagga ataagaggaa
    37981 tacttggaag aggatgtatg aatacaggag ctcaatttgg agttcatcct ggaataatgc
    38041 aagatgtaga aacggttgaa aaagatgtac gaagattgtt tgaaaaacac cataatacag
    38101 aaaatggaag aattaaaata ggagtagctc cggcggcaat atggtcaaat tctcaagaaa
    38161 tgcttgagat gctgtggaga gtagtaaaag aatatgatga tgctttattt acagtacata
    38221 tatcagaaac tccttttgat agagaagcag caaaagaatt gcatgggcaa tatgacatag
    38281 atgttttaga aaaattagga atacttggac caaatgtact tatggtacat tgtgtgtatc
    38341 taactgaaag agatatggaa cttgctaaaa aatatgacat gaaagtgtct cataatacag
    38401 caagtaatat gtacttatct tcaggtgttg caccagtgcc agaaatgctt aaaaaaggaa
    38461 taacagttag cttaggtgta gatggagctg ctagtaataa ctctcaagat atgcttgaac
    38521 ttatgaagtt aacagcactt caacataaag ttaataagtg tgacccatta gcaatgtcag
    38581 cagaaaaagt tcttgagttg gcaactatag atggagcaag agctattgga atggaagatg
    38641 agataggttc attggaaata ggtaaaaaag cagacttact aatattcaat ccaatgcttt
    38701 caccaaaagc tatacctatg cataatccag tatctacatt agtatattct tctagcatga
    38761 aaaatataga aagtgttata gtagatggaa atataataat ggaagattcg aaaatattga
    38821 caactgatga agataaagca ttaaaagagg ctcaagatac agctgagaga ctttgtgtaa
    38881 gaggaactat caagaataga atggaaggtc ataaatggaa tagcctttat taataaatgt
    38941 aatttattca taaaaaagta tagtaaaaac tttaacttaa aaatatgagt tttgaggtga
    39001 tttatttgat tatcaaatgt accataaata ataaagaaaa agaattaagc ataagaccag
    39061 atgatttttt agcagataca ttaagagaaa atggatatgt aagtgttaaa aaagggtgtg
    39121 atacaggctc atgtggctta tgtacagtga tggtaaatga caaggcagta ctttcatgta
    39181 attatcttac tgctagagta gatggtcagc atattacaac acttgagggt gtcttggatg
    39241 aagcgaaaga atttggagat tttcttgcag atgaaggggc tgaccaatgc ggattttgtg
    39301 ctcctggatt tataatgatg gtcttggcta tgaaaagaga gcttcaaaat ccaacagaag
    39361 aagaagttat agattatgta aatggtaacc tttgtagatg tacaggatat aaaggtcaat
    39421 taagagcaat acataaatat ttgaacactt agacttttaa gtgaaaatta agttgatatg
    39481 gggagagagt atgataacta taaaggaata tgtagttcca aaaagtttag atgaagctta
    39541 tgaactgcta atatcaagaa aaaataacat aatacttgga ggatgtggat ttttaaaact
    39601 aggtagtaaa aatattggtt cagcaataga tttaaaaaac ttagctttag attatataaa
    39661 tgaaactgat gatagtatat taattggagc agatacaagt ttaagaactt tagaattaaa
    39721 taaggttatt aaaaattact gtaatggggt aatttcaaac gctgtttcta atatagtagg
    39781 agttcaattt agaagtggag ctagagtagg agctagcgta tttgctaagt atggattttc
    39841 agatttaata ccttcattac tagtggtaga tgcaaaggtt aagttatata aaaaaggggt
    39901 tatgagctta gctgattttt tagaaagtga gcttgaaaaa gatatattaa tagaagttat
    39961 attacctaaa aaagatgcta taggtgtatt tgattctata agaaaatgta caggtgattt
    40021 tgcagtatta aatggagcaa tgttaaaaga aggaagtatt tataaaattg caataggtgc
    40081 tagaccaaga agagcaaaaa ttgcctataa agcaagtgaa atattaagct tagaaaatga
    40141 tatagaaaaa gctggcgaag tatcaagtga agaactttca tttggaagta atataagagg
    40201 aagtaaagaa tatagaaaag atatggcaaa agccttagta ttaagaatgt ataatagtat
    40261 tggaggtgag tgtgatggta aataaagagg taagaaaaat agatagtgaa gcaattgtta
    40321 ctggaaagcc aatatataca gaagatttaa tttttcataa agatgtttta acaattaagc
    40381 ttcttagaag tccacatgca tttgcgaaga taaaaaacat agatataaaa aatgcgttaa
    40441 aggtaaaagg tgtagtaaac atattcactt acaaagatgt tccaagttat agatattcaa
    40501 tggttgggga gtcatatcca gaagcatcac ctcatgacca attaatactt gaagacgtag
    40561 ttagatatgt aggagatgaa gttgctataa tagccgctga agatgaaagg gctgctatta
    40621 aagctatgaa acttataaaa gttgaatatg aagtaatgac tcctatattg gatgcaagag
    40681 aatcagaagg aaataaaatt ttaatccatg aagaagatga tttgttttgt ccatttgatt
    40741 ttggattgga tgctacaaaa aatatcgtat caagagaaaa aatgggtaaa ggggatgtag
    40801 aaaaagagtt taaagaaagt gatgtaatag tagaacattc ttatatgact caatcacaag
    40861 cccattgtat gatggaaact catagagctt atacatatat agatacgaat ggcagattag
    40921 tagtaacttc tgcaaatcaa tcagcttatc atatgagaag acaggtttct agagcattgg
    40981 ggatacctct ttcaaaggta agagttataa aaccaagaat aggtggaggt tttggtggaa
    41041 aaaacatagc tgtaacagag atatatgcat catttgtaac ttggatgacg aaaagaccag
    41101 caaaactaat ttatactaga gaagaaactt ttgcaatgac taatactaga catcagatgt
    41161 tttttgatat aaaaattggg gcagataaag aaggaaacat aaaagctata gatatgaaag
    41221 cattgaacaa tacaggtgct tatggtgata atggaccttc agtttgctct gaatcaggtc
    41281 ataatgtact tccaacatat aataatgtac ctgcaataaa atttgatggg aaaactgtat
    41341 atactaattt agttccaggg ggagcattaa gaggatatgg agcaacacaa ggtacatttg
    41401 cacttgattg tgcaattgat gaattagcgc ataaacttaa tatggaccca acagaaataa
    41461 agttaaagaa tattataaaa aaacaaactg aaggcggaat aatgaatttt ccaataagaa
    41521 gttgtgcact tgatgaatgt ataattagag gtaaaaaact tattggatgg gatgaaaaat
    41581 accctgttaa agatattgga aacaataagg tgagggctgt tggaatgtct gtgggaactc
    41641 atggttctgg tatagccaac atagatatgg caatagtaaa tatgaggatg gatgaagatg
    41701 ggacttataa gttgttttct gggtcttcag acttagggac tggttctgac acaatacttg
    41761 cacaaatagc tgcaaaagca ttgaacacat ctattgacag aatttctgtt tatacaggag
    41821 atacagatat gtgtccatat gatactgggg catatgcttc ttgtactact tatgtaactg
    41881 gaaatgctac aataaaatct gctgaaagtt taaaacgaaa gatattaaaa gtagcacaga
    41941 agaaacttga tttaccaata gatgatttaa tactatatga agatagagtt tgttatagtg
    42001 aggatgtaga gaagtttgtt ttgttaagtg aattaggaaa agaatctgtt ggtggtggaa
    42061 atcaagaagt tttatattca tctgaatctt atggtataca agagagtgct aaaccattct
    42121 tagcaggatt tgctgaaata gagttagata aaacaacagg ggagtttaaa gtaataaatt
    42181 atgcttgttc tacagattgt ggtacagtta tgaatcctgc acttgctaga atacaagttg
    42241 aaggtggtgt aactcaaggt atagggcttg caatgtatga agaccctaga catggttctg
    42301 atggaaagct tcagacttct aatttattac aatacaaagt tccaacaaaa aaagatatag
    42361 gaaatataat tgttgatttt gtagataatt atgagccaac aggtccatat ggagctaaat
    42421 ctttaggaga aatagttatt catacacctg caccagcaat agcaaatgca atatacaatg
    42481 ccacaggagt tcgtataaga gaacttccta taacttctga gaaagtttat atggccatga
    42541 aaaaattaaa tcagggaggt aaataaatga ttgctattaa aagtaaatac ttaatatctt
    42601 ctgctgatga aatatataca aattatgctg ttgtagtaga aaatgacatt ataaaagata
    42661 tattgccaaa tgaagaagtt gaaataaaat acaaaaatat tgaagaagta atagataaat
    42721 cagatgctat aataatgcca ggatttgtaa atggccatat gcatcaatat ggagttcttt
    42781 ctagaggaat accggcaaat gtacatttta ctgactttga aggtttctta aatgactatt
    42841 ggtggccatt tatagaaaat agaattggat tgaaagaagt aaaggcaaca actaaagcat
    42901 cagcaataga acttatagaa tctggtgtag tagctttttg tgatacccta gaagctccaa
    42961 atacagaaga aggaactcta attgaacaag gaaaaattct agaagagata ggcatgaaag
    43021 cggttttatc attagaaagt tgtgagagaa taagctttga aaatgggctt agatgtttag
    43081 acgaaaattc taatttaata aagtggagta gagaaaatag taaattaata aatggaataa
    43141 tgtgtacaca tacaagcttt acatgttcgg ataaatttat taagaaagct aaagaagatg
    43201 caaagaaatt aaatgcaccg atgcaatttc atttatgcga gagtatatat gaaccaaact
    43261 atgctgaaaa acattttggc aaaaaagcag ttgactacta taatgattta gatatattgg
    43321 atgaaactgt attagcatct cagtgtgtaa aagtaaatga tgaagaaata gatatattaa
    43381 aagaaaaagg cgtaaaagta gttcatatgc ctcttagcaa ctgtgaagta ggtggaggtt
    43441 tttctccagt accaaaaatg attaaaaaag gcataaaagt ggcactgggt actgacggat
    43501 atataaatga tttttttgaa gttatgagag gtgcattttt aatgcataaa tcagttgaag
    43561 aagatgcatc agtaatgcca gcaaatttag tatttagaat ggcaacagag catggtgctc
    43621 atgtattagg acttcaaaat tctggtaaaa tagcagttgg taataaggct gatataatag
    43681 ttatggaaga tgaatttaaa actcctgtga ctcttgataa tatatttgac cagatagtag
    43741 ttcagggtaa aaaagaattt atatcaaatg tatacataga tggtagacat attttaaaag
    43801 aaaaacagct agttgattta gataaaaaag ctattgttaa agaaatgaaa gaagttgctt
    43861 gtgaattttg gaatttttaa cgaatgtaaa tatatatgaa aaggggaagc agataatgta
    43921 caatttttta ggtaaagaat taaaatcacc acttataata ggttcagggc cattaacata
    43981 tagtgcggct ggatgcaaga tattaagtga tgcaggagca ggggcagttg ttactaagac
    44041 tataagaaaa gaaagagcta taaatccagc accacatatg gttagaaata cagctaatgc
    44101 tcttttaaat aatgagaaat ggacagattt tgagccagag caatggatag attttgaaat
    44161 accacaaatg aaaagagatg ggactgtatg tatagcttca gtaggtcata caattgaaga
    44221 aagcagcgaa ttagtagaaa aagttgcaaa tgcaggagca gactttattg aattagtatc
    44281 ttatgattat agagatttga taccaatgct taaagatgca aaggaaagag taaatatacc
    44341 agtaatagtt aaacttcctc ctatgataga tgagataggc gattttgcca aaaaattaga
    44401 agaagcagga gcagatgcaa taactgcttg tgattctgta ggaccagcat ttagaataga
    44461 catagaaaca gggcaacctt tattaggggg aaatggaata ggatatttaa gtggagaaac
    44521 tatcaagcca ataactttac agagaatata tgaaataaaa aaacaagtta atataccaat
    44581 aattggtcta ggtggatgtg taagtggaga tgatgcctta gaaatgatta tggcaggtgc
    44641 tgactttgtt ggtatatgtt cagtagtaat cttaaaaggt gcacaagtaa tatctaaaat
    44701 acatgatgac ttaaaatcta atcttaatag attaggatat aatactatag aaaatgcttg
    44761 tggaatagta cataatcata tgggagatgt taatgaaaga cttagctttg agtttactta
    44821 tgatgaagaa aaatgtacta aatgtaagat gtgtgagaga gtctgtgcat atcaagcgag
    44881 aaaattgaat gataaaatgg aattgaatga agaagagtgt agatattgtg gactttgtat
    44941 atcagtttgt aaaccaaaag cacttggaag aaaaatttca tgttcagagt tgaatgtata
    45001 gattatttta taaaaaataa agttttaaat aaaaataaga aggcctatct caaaatagag
    45061 ataagccttt tttgttgacc ttatttttgt ttatttatag ttattttaga tattaattag
    45121 ttttgaagta ataaagtgcg taaattttgt ttaattaaaa ttttaataat tcttatatat
    45181 atgttaacat tgtatagcat ttgtgtaaaa tgttataata attaataggg atggtgatgc
    45241 aagtgcaaga gaagatttta gaattattgt atactataaa tgaagatgta gttagcataa
    45301 aaaatgatat gtcagaagta aaacaggaaa taaatgtgtt aaaagaagat atgtcagaag
    45361 taagacaaga aatgactgta atgaaagaag atatgtcaga agtaaagcaa gaaataaata
    45421 taatgaaaga agatgtgtca gaagtaagac aagaaataaa tatattaaaa gaagatatgt
    45481 tagaagtaaa acaagagata aatataatga aagaagatat gtcagaagta aaacaagaga
    45541 taaatataat gaaagaagat atgtcagaag taagacaaga aatgactgta atgaaagaag
    45601 atatatcaga ggtaaaacaa gagataaatg tattaaaaga agatatgtca gaggtaagac
    45661 aagaaatgac tgcaatgaaa gaagatatgt cagaggtaaa acaagagata aatgtattaa
    45721 aagaagatat gtcagaggta agacaagaaa tggctgtaat gaaagaagat atgtcagagg
    45781 taaaacaaga gataaatgta ttaaaagaag atatgtcaga agtaagacaa gaaatgactg
    45841 taatgaaaga agatatgtca gaggtaaaac tagaagtaac tgtaatgaaa gaagatgttt
    45901 ccgaagttaa atcagaagta aactttatgc aaaataaaat aaataatatt aataaagata
    45961 tgagtggaat taaggaagaa gtatccatag caaatgaaaa attagatgga attgaaatta
    46021 agattgatag tctagaaagt gaagataagt caatgaaaga gatgcaggta gaacagaata
    46081 atattttagg aagcttatta cataattctg aaataaataa agctactcat gataatatag
    46141 aacataacat agcatatata aaaggagata ctaattctat aaaagaggat atagctgaaa
    46201 taagaagaga cttaaattta gtagagttag ccactagtaa aaattggagt gatattgtca
    46261 aactaaaatc agtaaagtag tattttaatt cactaattta tcatccacaa acataaaaga
    46321 atttatagtg ttcttactat ttattataaa ttttagaaat gaaaataaaa aattgagaaa
    46381 agaccgttaa aaatttattt ttaggtcttt tttttatgca aatataactg atttataaaa
    46441 ataaaaccta aaatttaaat gataaaatct aatagaacga ttgaaataag taaaatttta
    46501 tcaataaaaa cataa
//
LOCUS       DBGJFK010000027        44794 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.027, whole genome shotgun sequence.
ACCESSION   DBGJFK010000027 DBGJFK010000000
VERSION     DBGJFK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44794
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.027"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            109..711
                     /locus_tag="ACOIAP_001746"
     CDS             109..711
                     /locus_tag="ACOIAP_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="HGZ2638632.1"
                     /translation="MKSLKKILIVTGCLTIISTSLAFASTNNDVNVSKSNEDQATNSF
                     TITGYEFTYENAPQPIKSDYEKKCKELNINPSKNDTIFINEKFIDSYNINIDDYNIEP
                     KAFIIRYKKDLNRFDVTGPISYSVNINTTVVGYGHIEKGNPVHLVQLLCQQINGSSIN
                     PDSKFGPDTYNQVKILQGRLGVTKDGVVGKATWQAAGERY"
     gene            complement(845..1861)
                     /locus_tag="ACOIAP_001747"
     CDS             complement(845..1861)
                     /locus_tag="ACOIAP_001747"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HGZ2638633.1"
                     /translation="MNYNDLLKSARENFNEKCKVCKICNGLACAGNVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTLLNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNCGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQLQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMTVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKAVKGKITILVDGGVRSGVDV
                     VKMLGLGADAVLMGRPFVIASFGGGLDGVEFFIEKVRSELCETMILTACQNVKDIDGR
                     VIWK"
     gene            complement(2191..2373)
                     /locus_tag="ACOIAP_001748"
     CDS             complement(2191..2373)
                     /locus_tag="ACOIAP_001748"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638634.1"
                     /translation="MYKDESDECIHLMTAYIDSLSGYYSFIDTQLEDFMVKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            2689..3108
                     /locus_tag="ACOIAP_001749"
     CDS             2689..3108
                     /locus_tag="ACOIAP_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HGZ2638635.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYVFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIIQIENCIV"
     gene            3239..5080
                     /locus_tag="ACOIAP_001750"
     CDS             3239..5080
                     /locus_tag="ACOIAP_001750"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HGZ2638636.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLNNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGVSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDINKANLYIDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIEA
                     LYIKIKKINDFNCKKMYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPMA
                     INNLAKSEVYLEKIKNQNLKEVAKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     IMKNIEEYTMYDLEIIYHQAKIYYIFGYYENALNTNKKLLEKSKNAKNYNYVKLAYKN
                     IYLCFEKIQDYEISMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYIDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITMIIKKYLKKDMLMIRYGGEEFLILSICKDYKKSKIFGRKLCRTVKKFLNNNL
                     TVSIGIDTCKNSSIDIREIIKNADKALYKAKESGRNRCLHYNDFKNF"
     gene            5122..6993
                     /locus_tag="ACOIAP_001751"
     CDS             5122..6993
                     /locus_tag="ACOIAP_001751"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2638637.1"
                     /translation="MEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNTKLEDD
                     SRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDVYVISKIYIYLTLSAIS
                     IRKYDKANNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIDLVEEVSFF
                     KNLNNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLRLAQENNLYSIEAFCKCIIS
                     LCYLESGNNVEAIKYINNVLDVAHNNNSISVTERVSIKIDLIWAYLKEDMNKEAEVIL
                     LKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYESFGDV
                     FIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYGLIANG
                     YELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLVDDNKK
                     LENDILKDGLTKLYNRRYLEQQLNLFNGTRDKNMVAILVDIDCFKSYNDNYGHLAGDK
                     VIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESISVEEIDNIELYIKRVFKLLE
                     FEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEMLIEDADKNLYKSKKAGRNQYIII"
     gene            7001..9001
                     /locus_tag="ACOIAP_001752"
     CDS             7001..9001
                     /locus_tag="ACOIAP_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2638638.1"
                     /translation="MILLQKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEAVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEIDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRNFKTKQSLSNSEVDKFNSETTASAEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            9263..10522
                     /locus_tag="ACOIAP_001753"
     CDS             9263..10522
                     /locus_tag="ACOIAP_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGZ2638639.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKALGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINS"
     gene            10583..12370
                     /gene="iorA"
                     /locus_tag="ACOIAP_001754"
     CDS             10583..12370
                     /gene="iorA"
                     /locus_tag="ACOIAP_001754"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043805 - indolepyruvate ferredoxin
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HGZ2638640.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKDYVKNAKKMVTVPANAQIRRGVVEERMETLKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTSDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDNNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            12372..12947
                     /locus_tag="ACOIAP_001755"
     CDS             12372..12947
                     /locus_tag="ACOIAP_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HGZ2638641.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELNRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            13000..14070
                     /gene="buk"
                     /locus_tag="ACOIAP_001756"
     CDS             13000..14070
                     /gene="buk"
                     /locus_tag="ACOIAP_001756"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HGZ2638642.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDNGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGKYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGNVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            14286..14987
                     /locus_tag="ACOIAP_001757"
     CDS             14286..14987
                     /locus_tag="ACOIAP_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2638643.1"
                     /translation="MGKMNLKSMARLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVIIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVLMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSD
                     EHKCKSSIVIKNEQN"
     gene            15047..15553
                     /locus_tag="ACOIAP_001758"
     CDS             15047..15553
                     /locus_tag="ACOIAP_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGZ2638644.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEDGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEESLEGAIREAKEEIGIDITKDEMKIFRSMTH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLSE
                     IDNNKLNI"
     gene            15726..16748
                     /locus_tag="ACOIAP_001759"
     CDS             15726..16748
                     /locus_tag="ACOIAP_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGZ2638645.1"
                     /translation="MEDNKGLAHDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSYLNIPDSLIIIVLYALFAMLLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKKFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMRFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAIETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(16893..17201)
                     /locus_tag="ACOIAP_001760"
     CDS             complement(16893..17201)
                     /locus_tag="ACOIAP_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HGZ2638646.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINEKNASCETFEMK
                     "
     gene            complement(17261..17689)
                     /locus_tag="ACOIAP_001761"
     CDS             complement(17261..17689)
                     /locus_tag="ACOIAP_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638647.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIKCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFTCSICGSTENVDVYHVNKNLGRETSKDVVVKCNKCICK"
     gene            complement(17910..19367)
                     /locus_tag="ACOIAP_001762"
     CDS             complement(17910..19367)
                     /locus_tag="ACOIAP_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HGZ2638648.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGIIFLYYLCATLFPIDKIIGKIYPIFGAILLLSAAGVGVGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELIGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIVKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNM
                     NISYVLAAIFTVLYAILTVHSGRKLKSRADTKLAD"
     gene            19785..20699
                     /gene="nadA"
                     /locus_tag="ACOIAP_001763"
     CDS             19785..20699
                     /gene="nadA"
                     /locus_tag="ACOIAP_001763"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HGZ2638649.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTILMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYITLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            20712..22013
                     /locus_tag="ACOIAP_001764"
     CDS             20712..22013
                     /locus_tag="ACOIAP_001764"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HGZ2638650.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMRAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFVDIPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            21994..22830
                     /gene="nadC"
                     /locus_tag="ACOIAP_001765"
     CDS             21994..22830
                     /gene="nadC"
                     /locus_tag="ACOIAP_001765"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGZ2638651.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGNVGVELYKNDGDRVENREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSKYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGGVKNAVELARKNTSFVRKIEVEVETLDMVKEAIEAKADIIMLDNMSL
                     EMAKQAVDIINGRAIIEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            23088..23420
                     /gene="saoD"
                     /locus_tag="ACOIAP_001766"
     CDS             23088..23420
                     /gene="saoD"
                     /locus_tag="ACOIAP_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE-related protein SaoD"
                     /protein_id="HGZ2638652.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPIGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            23510..23767
                     /gene="saoT"
                     /locus_tag="ACOIAP_001767"
     CDS             23510..23767
                     /gene="saoT"
                     /locus_tag="ACOIAP_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_240067706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:23543..23545,aa:Sec)
                     /transl_table=11
                     /product="thioredoxin-like (seleno)protein SaoT"
                     /protein_id="HGZ2638653.1"
                     /translation="MSKILVEFINTUPSCDEHGVFIKKMSEKYADKLEIKLYQAGKDF
                     SYIKKYGIVTKGTLIINQKKKYDRLNKDTIERAIVEAINNN"
     gene            23795..24880
                     /gene="saoE"
                     /locus_tag="ACOIAP_001768"
     CDS             23795..24880
                     /gene="saoE"
                     /locus_tag="ACOIAP_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter SaoE"
                     /protein_id="HGZ2638654.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGSKVTIIYLISGFLVPFLVGFLGNCFGKEELSLHNDLEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAAIVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            24873..25331
                     /gene="saoC"
                     /locus_tag="ACOIAP_001769"
     CDS             24873..25331
                     /gene="saoC"
                     /locus_tag="ACOIAP_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Cys-COOH (seleno)protein SaoC"
                     /protein_id="HGZ2638655.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            25360..26445
                     /gene="saoX"
                     /locus_tag="ACOIAP_001770"
     CDS             25360..26445
                     /gene="saoX"
                     /locus_tag="ACOIAP_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding subunit SaoX"
                     /protein_id="HGZ2638656.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKQKEEAKAGKDDYTITVG
                     YYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGAIP
                     KGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLPTD
                     PSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKANGK
                     EYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEVAL
                     RTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGADD
                     FDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            26459..27247
                     /gene="saoB"
                     /locus_tag="ACOIAP_001771"
     CDS             26459..27247
                     /gene="saoB"
                     /locus_tag="ACOIAP_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:26672..26674,aa:Sec)
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     (seleno)protein SaoB"
                     /protein_id="HGZ2638657.1"
                     /translation="MKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTSGFV
                     INYMVNRDYFENIKVSDIMDIFTINDCUASTMQWALSSEEIDIAIICKDAAKQYVNVN
                     SGFEIVGTVVQNSDIFLLSDNNPKKMGVIQNRDYQSELVKKYYKNVEVAPLLGTALAY
                     GLESNLVDGVVIDCIKSIGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYN
                     KSVDALKNKATFKKALKEYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            27271..28014
                     /gene="saoP"
                     /locus_tag="ACOIAP_001772"
     CDS             27271..28014
                     /gene="saoP"
                     /locus_tag="ACOIAP_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_239591060.1"
                     /note="Most members of this family are selenoproteins with
                     the selenocysteine residue at the channel-gating position;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:27835..27837,aa:Sec)
                     /transl_table=11
                     /product="ABC transporter permease subunit SaoP"
                     /protein_id="HGZ2638658.1"
                     /translation="MDILYKIILLVIIFLVWHFAAKDIGSSLLLPMPVDVIKGFFFCV
                     TDAETVTNLFITLQRVLKGFIYALLFGLPIGFIMGFSKTFERVLSPVVDSVRQVPIMA
                     WVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVRAISKDYYNAARSMGASPIVIF
                     TNVIIPASLPDILTGSRIAISTGWMSVIUAEFIATSAGLGYSMVQAQTLMHTDVLIGL
                     MIFAALIGFIIDRVLKFINKILCRWRFAD"
     gene            28014..28766
                     /gene="saoA"
                     /locus_tag="ACOIAP_001773"
     CDS             28014..28766
                     /gene="saoA"
                     /locus_tag="ACOIAP_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein SaoA"
                     /protein_id="HGZ2638659.1"
                     /translation="MKLSVRDINKTFVNNRVNTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSESGDVFINDKKVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEILLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            28779..29420
                     /gene="saoL"
                     /locus_tag="ACOIAP_001774"
     CDS             28779..29420
                     /gene="saoL"
                     /locus_tag="ACOIAP_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_238476746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018942 - organometal metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:29262..29264,aa:Sec)
                     /transl_table=11
                     /product="MerB-like organometallic lyase SaoL"
                     /protein_id="HGZ2638660.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNMEKEYIESTLQYFIDKNIMVVDGDSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDVRINSICSVTGREIEIVIKNEKIEYVNNPSLRVLHINLDKYSNWAAN
                     CUNIMNFFWTKSDFDAWTIEAGLSDDEDIYCLDINEAIVESYKIFKLKQKIIL"
     gene            complement(29552..30373)
                     /gene="yidA"
                     /locus_tag="ACOIAP_001775"
     CDS             complement(29552..30373)
                     /gene="yidA"
                     /locus_tag="ACOIAP_001775"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGZ2638661.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNDIEVKYIQKDKIDESIKICKIMIVDEP
                     EKLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCANLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            30867..32561
                     /locus_tag="ACOIAP_001776"
     CDS             30867..32561
                     /locus_tag="ACOIAP_001776"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HGZ2638662.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLGCVEDINNSHNYKEQQKNIHKLN
                     LLRNKIETLSNIALIRYSTDTLNKFYQEEKDYWDEYMPLYEELNSHFYNAIVNSKFKC
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKIRELANKAYYNFFEKNETKFDDIFDKLVKLRDKISKKLGFEDFVEL
                     GYIRMMRSDYREDMIKSVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFNFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSAIKFIPYGVIVDEFQHYIYKNPNIDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLDRGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DTGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      32893..33003
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            33107..33478
                     /locus_tag="ACOIAP_001777"
     CDS             33107..33478
                     /locus_tag="ACOIAP_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HGZ2638663.1"
                     /translation="MIIITNNPKVKEEVQDREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVVLKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            33574..34521
                     /gene="trxB"
                     /locus_tag="ACOIAP_001778"
     CDS             33574..34521
                     /gene="trxB"
                     /locus_tag="ACOIAP_001778"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGZ2638664.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            34607..34924
                     /locus_tag="ACOIAP_001779"
     CDS             34607..34924
                     /locus_tag="ACOIAP_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HGZ2638665.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            35191..36477
                     /locus_tag="ACOIAP_001780"
     CDS             35191..36477
                     /locus_tag="ACOIAP_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HGZ2638666.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            36590..37063
                     /gene="grdA"
                     /locus_tag="ACOIAP_001781"
     CDS             36590..37063
                     /gene="grdA"
                     /locus_tag="ACOIAP_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_110943085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:36722..36724,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HGZ2638667.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            37095..38405
                     /gene="grdB"
                     /locus_tag="ACOIAP_001782"
     CDS             37095..38405
                     /gene="grdB"
                     /locus_tag="ACOIAP_001782"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030700 - glycine reductase complex
                     [Evidence IEA];
                     GO_function: GO:0030699 - glycine reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:38142..38144,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HGZ2638668.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            38652..40184
                     /gene="grdC"
                     /locus_tag="ACOIAP_001783"
     CDS             38652..40184
                     /gene="grdC"
                     /locus_tag="ACOIAP_001783"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit beta"
                     /protein_id="HGZ2638669.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIVGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            40195..41340
                     /gene="grdD"
                     /locus_tag="ACOIAP_001784"
     CDS             40195..41340
                     /gene="grdD"
                     /locus_tag="ACOIAP_001784"
                     /EC_number="1.21.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     component C subunit alpha"
                     /protein_id="HGZ2638670.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFADIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            41646..42725
                     /locus_tag="ACOIAP_001785"
     CDS             41646..42725
                     /locus_tag="ACOIAP_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGZ2638671.1"
                     /translation="MSKVKKVVELLESKGIDALYLTKKTNVNYISGFPDEEAYAVICK
                     YGNFLVTDSRYMELAENVCEGFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYIKDEEEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGEASEKQLEIYNLVKEAQNVGVENMKVGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEDGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            42836..43435
                     /locus_tag="ACOIAP_001786"
     CDS             42836..43435
                     /locus_tag="ACOIAP_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638672.1"
                     /translation="MYKKHKFIKNIKQAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSVNFIKRPSRKYINTDVSSNFFIDNNLSKKSQE
                     SSQNNVMNVKNTIGFTSETDNYEKKIPTNNTEDFEDGETSELQIVIATVICVVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSRPD"
     gene            complement(43615..44487)
                     /locus_tag="ACOIAP_001787"
     CDS             complement(43615..44487)
                     /locus_tag="ACOIAP_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2638673.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISSYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTKNLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
BASE COUNT        17574 a         4853 c         7951 g        14416 t
ORIGIN      
        1 cagatcttaa ggaagaagat gatattagtg tgagagttgt aaattaacat atttttgcag
       61 tgttaaaaga acattataat ttattaacaa attaggagga attttgaaat gaaaagtcta
      121 aagaaaatct taatagtcac agggtgcttg actataatat ctactagttt agcatttgca
      181 agtactaata atgatgtaaa tgtatcaaaa agtaatgaag atcaagcaac aaattcgttt
      241 acaataactg gttatgaatt tacttatgaa aatgcaccac aacctataaa atctgattat
      301 gaaaaaaaat gtaaagaatt gaatataaat ccatctaaaa acgatacaat ctttattaat
      361 gaaaaattta tagattcata taatattaat atagatgatt ataatattga accaaaagca
      421 tttattatta gatataaaaa agacttaaat cgttttgatg ttactggacc tataagttat
      481 agcgtaaata taaatactac tgtagtaggg tatgggcata tagaaaaagg taatcctgtg
      541 catttagtac aacttttatg tcaacaaata aatggttcta gtattaatcc agatagtaaa
      601 tttgggcctg atacatataa tcaagtaaaa atacttcaag gaagattagg tgtaacaaaa
      661 gatggtgttg ttggaaaagc tacttggcaa gctgctggag agcgttatta gaaaagaggt
      721 tgtcgcacta agaaataggg cggcaacctt tttatataga gtatattaat cagtatcttc
      781 taaaaatagt tgttattata tctaaagagt ctggaaatat aagtgttata aaactatttc
      841 acaatcactt ccatataact ctaccatcta tatccttaac attttgacaa gcagtcaaaa
      901 tcatagtctc acacaattca cttctaacct tctctataaa aaactccaca ccatcaagac
      961 caccaccaaa agaagcaata acaaagggtc ttcccatcaa aacagcatca gcacctaaac
     1021 caagcatctt aacgacatca acaccacttc taacaccacc atcaacaagt attgttattt
     1081 ttccctttac agctttagct atatctggta gtacctcaca agtaccaggg gtataatcaa
     1141 gtactcttcc gccatgattt gaaacaataa tagcactagc accagattct acagtcatca
     1201 aagcatcatc tacagtcata attcccttta taataaaagg caatctagta gactcaacca
     1261 attctctaat ctcatcaatt gtcttaggag aaaaaggatt ttcttgaagc tgattattga
     1321 taagtccaca agcatcaagg tctacaccaa ctgcaaaagc acctgcttct tcagacaatc
     1381 taatcttttc tattatcttt gaattattcc aaggctttat aaatacaatt ccatttccac
     1441 aattatcttt taacacatct aaattatcca gtaaaaaagt atctacattg gtatcgccaa
     1501 ccatagcata aattccagaa ttagaacaac ctctaacaac aggttctatg tattcttttt
     1561 cagaaacttt accacccatg ttcaataaag tacctgatac aggggcagcg aatataggag
     1621 aactcatttt tctaccgaat aattctatag atgtatctgg ctttgaaaca ttatgtatta
     1681 ctctcatatt tatctttatt ttttctagac tctttctatt ttcaatgaaa gatgaaccac
     1741 ttcctttacc acccatacca ggaacatttc cagcacaagc caatccatta caaattttac
     1801 atactttaca tttctcatta aagttctctc tagctgattt tagtaagtca ttataattca
     1861 tacaaaatct ctccttttta taatattaaa attaagcatt actatattga aaatatctta
     1921 gttgtaaata tagagatgat gttatgatga gataaactag ataatacata ttagatattt
     1981 tttattgttg cagatagtta aattatatca tattagatag taaaattttg aaaaaaacta
     2041 acttatttaa gtatacattt taaaaaaatt aaaaaagcta tatatagatt tttaaagaaa
     2101 tctatatata gcttttaagt ttatgacaat ctttttttat taatgaataa ataatataga
     2161 atacaatgta caaaaaagct tcttaaaatg ctaagataat ccccatttac aaagcaacat
     2221 cattatacta tgcaagtttg aatcaacaat gttttcacca tatttcacca taaaatcctc
     2281 taattgtgtg tcaataaatg aataatatcc acttagacta tctatgtatg cagtcattaa
     2341 gtgtatacat tcatcactct catctttata catatatatc tccacctata tacaatatat
     2401 aaatttagat actaaatcgt atcatattaa atagttaagt atgtcacatc tatgtagtta
     2461 tatatttata tccttatatt aataactaaa gtgaattttg acaatagatt ttgggaaact
     2521 ggatgttcaa aatgtaaact tggattttaa aatgattaat taaaatagtg catagtatat
     2581 atgtatacat aaattaatta attataaaga ttataaacaa ttacttttat taactttatt
     2641 taagtggtag aataacttgg agattaataa ttataaggag gatataatat gagtttatat
     2701 aagtttatat atgatgataa ggaatattta ttaaaagagg agaattgtag tgctttaata
     2761 aatgatgaag aaaatccagt tcaaggagta agtatttcaa aaataattga tatacttaat
     2821 gaagcagaag aagttgattt tgatgtagaa tattatcaag aagcatgtcc attatgttta
     2881 gaaggggtaa aggaaaagaa aaaattcttt ccttttttgg aatatcactt ttatgttttc
     2941 agtaaagatg gagaatatgt aataagtaat atatctgttg attataaagg attatctttt
     3001 aataaactat caagggcaaa taaagttgat aatagttata ttgtaagtgt gataatttgt
     3061 gaaaattgtc aggattatat aattcagata gaaaattgta tagtttagtg taaagtatgt
     3121 cttaatttaa gagaaatttc taaattgaga catcgacttt tttcaaaaat agtatggaaa
     3181 attactaaat ttatgagata atgtaagtcg gaggtgagtt acaatatata gtaaatattt
     3241 ggaagagata gatgatacaa ttttagattc aatgtttaag ctaaccttga atgaaagatt
     3301 attgaataat aacgatttta ttgaaaataa aattgatgta gtaaagaatt taatcgattg
     3361 ctataaaacc gaacaaaata gtttgatgtt attaaaatca aattttttgc tagctttatt
     3421 atatggtatt caaggggtta gtgaaaaaat gaaagagtat attttgattt cctgtaaata
     3481 tattgataaa tgcttaccca aagattataa gtttctagca cgattttatt cacaaatagc
     3541 tattttaagt ttaaaaaatg aagatataaa taaggcaaat ttatatatag ataaatttaa
     3601 tcttatttgt gatgaaaata attttctaat tgaagaaatt atttttaaat cacaacttat
     3661 ttatattaag gcaagtaagt gtatagaatc ttctgtaata attaaagaaa tagaagcttt
     3721 gtatataaaa ataaaaaaaa ttaacgattt taactgtaaa aagatgtatt tttttattat
     3781 tggtaaaata tattttttat ttttagatga tgctctaatt gctaaggtga attttttaaa
     3841 agcaagaaaa tatgcagatt tactaaagga tatgcaagta tcttcattat gtaatataaa
     3901 gataggcgag tgtgaatgtt catttgaaaa ttatgaatgt tcgatggaat atttcaatga
     3961 agtaataagc aataaaaagt atagaaatgt aaatataatt caaaaatata gagcatcaaa
     4021 caatataact aaaatattaa taaagactag aaattatcct atggcaataa ataatttagc
     4081 aaaatccgaa gtatatttag aaaaaattaa aaatcaaaac ttaaaagaag tagcgaagtt
     4141 tgatttattt ataagcttag ctatgtatta tgcaaaaagt aatgaaaaat cttttgaaca
     4201 atcaatctgc tatttagata gagctaaaaa catattaaat ataatgaaaa atatagaaga
     4261 atatacaatg tatgatttag aaataattta tcaccaggca aagatatatt atatctttgg
     4321 atattatgag aacgctttaa acacaaataa aaaacttctt gaaaaatcta aaaatgctaa
     4381 aaattataat tacgtgaagt tagcatataa gaatatatat ttgtgctttg aaaagattca
     4441 agattatgaa ataagtatga aatactttaa aatgtattat gagttaaaaa tgatgtatat
     4501 aaaagctcga aatagaaatt atatagattc tttaaattat agacatgagt atatagaaaa
     4561 agaaataaat aacatgagaa aagtaaaact tgatttagat aaaaaaaagt atattgacca
     4621 tttaacaagt gcatataata gaactttttt gaacgatttt ttagaaaaac aagaagttag
     4681 tgaatattgt acagcattta tgatagatgt agattacttt aaagaataca atgatactta
     4741 tggacactat aatggagata ttgctcttaa aaatataact atgataataa aaaaatatct
     4801 aaaaaaagac atgcttatga taaggtatgg aggagaagaa tttctgatat tgtctatatg
     4861 taaagattat aaaaaaagta aaatatttgg aagaaaatta tgtaggactg taaagaaatt
     4921 tttaaataat aatttgacag ttagtattgg cattgataca tgtaaaaata gtagtataga
     4981 tataagagaa ataattaaaa atgctgataa agctttatat aaagcaaagg aaagtggtag
     5041 aaatagatgt ttgcattata atgattttaa gaatttttaa ctgttgaaat aggattggtg
     5101 atttacttga aaaggagttt aatggaagat ttaaaaagaa atataaacaa gatagaatac
     5161 gatatgttga ctaaattcta tctaaattta acagacttaa actacatctt ggattatcac
     5221 aaagaccttt taaatacaaa actagaagat gatagtagag tatatacttt atatttaatt
     5281 agtcttataa actatataaa aaaagataga gaagcatcat acaactattt gatagagtca
     5341 ttaaagtata ttaagaaatt gtcattaaag gatgatgtat atgtaatatc taaaatttat
     5401 atttatctta ctttatcagc tatttctata agaaaatatg ataaggcaaa taatttttat
     5461 ttctcagcaa aaaaaattat aagacaaaac catttaaatg agttgttggt cttgttaaat
     5521 atgagtttat gtgtagaaat aagtgcttta tatcagacca aaacggatgt aatagattta
     5581 gtagaagaag tgtctttttt taaaaattta aataataaag ctcttgtaag tagggcaaat
     5641 tatatatttg ggagagttta tctatattta tttaataact ttataaaaag tatggagtac
     5701 ttaattgaat gcctaagact ggctcaagaa aataacttat actctataga ggctttttgt
     5761 aaatgtataa taagtttgtg ttatttagag agtggaaata atgtagaagc tataaaatat
     5821 ataaataatg tattagatgt tgcacacaat aataactcaa tatcagtaac tgaaagagtg
     5881 tctataaaga tagaccttat atgggcctat ttaaaagaag atatgaataa agaagcagaa
     5941 gttattctat taaagactat aaaattaatg aaagttgttg aaggtgtata taaggattat
     6001 ttatattcat ttatattttt atattcagct gaaattgagt tgaagaaaga taattgtagt
     6061 tttgaaaagg taaataccta tttaatttta tcaaaaaata tatatgaaag ttttggagat
     6121 gtttttatat ataattctaa actagattac atatataagt tgtatggaga tttatatata
     6181 aaatttggca atatagacga aggtataagt tgttatataa aaggtttaaa tttagttaaa
     6241 aagagttcat taaatcttag gaaaatctct atattttatg ggctgatagc aaatggatat
     6301 gagctaaaaa aagattttaa acttgcaata gaatattata aaagtatgga ttggtattct
     6361 gatagatggg aaaaaaataa ttcctataaa acatctcaag caattcacaa acaatatgaa
     6421 cttagacaaa aacaagagag tttaagatta ttagtggatg ataataagaa attagaaaat
     6481 gacattttaa aagatggact tactaaacta tataatagaa ggtatttgga acagcagttg
     6541 aatttattca atggaactag agataaaaat atggttgcaa tactggttga tatagattgt
     6601 tttaaaagtt ataatgataa ttacggtcat ctagcaggag ataaagttat agttaaggta
     6661 actgatatta taagaagtgt atttatagat attactgaac acataatcag atatggggga
     6721 gaagaaattc taatactagt agattctata gaatcaataa gtgttgaaga gattgacaac
     6781 atagaattat atattaaaag agttttcaaa ctgcttgaat ttgagggtat cgaacatata
     6841 tattctaaaa taaaaaacta tataactata agtgctggag taagtataaa aagatgtcgt
     6901 agtagaaaag atgttgagat gttaattgaa gatgcagata agaacctata taaatcaaaa
     6961 aaagcaggta gaaatcaata cattataatc taaaattgag gtgattttat tgcaaaaaaa
     7021 aataggaatt atagcctctg atattgaatt aaaagaaaga atagaagaat tatatagaga
     7081 agatgtagaa aatgggacta taataatcga catacttaac ctagacttaa tggaaaatca
     7141 aggtcgtata cttgttgaaa aaggtgctca agccataatt ggtaggggtg gaggttatag
     7201 tttagtaata gatacagtaa atgtacctgt tataccaatg aatatgaagt caactgacct
     7261 tttaagagca atagaaatag caaagaaata ttctaaaaaa gtagtattaa ttcttggaga
     7321 caatgaagtt tcttttgact atgttggctg gagaaatgtc ataagtactg aaataactga
     7381 agaatggttt gaatctaagt atgagataag aagtaaagtt gtaaaatata tagaccaaaa
     7441 agatgaagtt gtaatcgtag gtggaggttt ggcatgttct tttgcaaggc aatatggaat
     7501 tgatagtgta tttgcaactg ctagtgatga atctataaga gaagctgtag aatattgtaa
     7561 aaagttgttg gatacattag gtgaagaaaa atttaataat gaagtgttac gaaatatact
     7621 tgatggtata aaagatggag taattgctat agatagtaat ggtagtataa ttttgtacaa
     7681 tgaaagcgca aaaaatatgc ttaaagtaga gagaaaatgt gcgcttaata aatacatttt
     7741 agatgtattt cctaaaatgg agtggatgtt agattgttta catgaaaaag aggctgtaga
     7801 agatagaaaa ataagaaata taaataattt aattgttaat actagaacga cattgataaa
     7861 agttgataat agtacttatg gagttttagg aataatacaa gatataacca agctacaaaa
     7921 cttagaaaga aaaataagat ttgacttgaa tcaaaaaggt ctttatgcta gatatacttt
     7981 tgatgatttt ttatttaaag ataaattaac taaagaattt attgaagaag ccaaaaaaat
     8041 tggaaaaagt gattatacaa ctttacttta tggagaaagt gggtcaggta aagaaattat
     8101 agcccatagt atacacaata taagtaaaag aaaagataga ccctttgttg ccataaactg
     8161 tgctactata gcagaaaatt tacttgaaag tgaacttttt ggatacgaag aaggtgcatt
     8221 tactggtgct agaaagggtg gaaaaagagg attgtttgaa cttgctcatg gaggtactct
     8281 ttttctagat gaaataaata gtctatcttt taatattcag acaaaactac taagagtaat
     8341 agaggaacgt caaataatga gaattggttc tgattatata atacctctag atataaggat
     8401 tatagctgca acgaatgaat ctttaaccga aaaaatagtt atgggtacct ttagggcaga
     8461 cttattttat agattgagta gtttagagat aaacatccca cctttaagag acagaagaga
     8521 agatataata cctttgttta acaattttgt aaatgaagta ttgaaggatg atggtctcaa
     8581 tggaataaac agtatagatg aaaattttgt tttgactaaa gatgaaattg ataagctata
     8641 taattatagt tggcctggaa atgtaagaga gttaaagaca atagctcaaa aatatgttgt
     8701 gacaggtaaa attaaattga gacaagatag gaattttaaa actaaacaat cactttctaa
     8761 ctctgaagta gacaaattta attctgaaac gacagcaagt gcagaagtcc aagatgagtc
     8821 tataaatata agtaaaataa atgatggtaa gataagtata gatataaaag aagtaaataa
     8881 gtatgttgaa gaaaaaataa taagtatgct ttttgctcag gggctttcta aaaatgaagt
     8941 tgcacaagtt cttggaataa gtaggacatc tttatggaag aaatataata aaaatattta
     9001 aatataatta catataaatt attttgaagt aatgttaatt tttttaaaca agtgttaaga
     9061 aaaattaaca ttattttttt gcaaattttt atttttttag acaagcatat atatttataa
     9121 gaaaaatagc taaaacactt aatttaataa tgaaaaaaat aataattcta aacaaaatca
     9181 gttttacata aagtggaatt tattggcata ataattgctt aatatataat gcaagagtaa
     9241 atacaatttt aggggtgatg gtatgagtca aagtatggtt ggtaagcatg caatgtggcc
     9301 aaaagaaaat gatgttatat ttagcatatc tggtagagct caagcagcag agaaggctct
     9361 cggtatggat aatgtaataa atgcaacaat aggcgcgcta atggatgatt caggaaaatt
     9421 aataacaatg aaaactgtat atgaagaata taaagcatta gataactgtg agataggtgc
     9481 atatgcagct cttgaaggtc aaccagatta cttagaagca gttaaaaaag tatttttcag
     9541 agattactta ccagaaggac atataagagt attagcttca ccaggaggaa gtggtgcaat
     9601 aaaattagct gtatggaact atactaatga aggagatgag gtattaacat ctgattggtt
     9661 ctggagtcca tatgtaagta tagctgaaga ggctaataga aaagtagtta attaccaact
     9721 ttttgatgaa aatagaaggt ttaattttga gtctttcaaa gaaaaatttg taaatatagc
     9781 agaaaaacaa ggtagagttt ttacaattat aaacacacca gcacacaatc caactggata
     9841 tagtgtcgca gatgatgagt gggataaaat attagactta tcaaaagaag ttgcaaaaga
     9901 taaagacaaa aagataatat ttttcgtaga ttcagcatat attgactttg caggtgatga
     9961 tgatgtatgt agaaagtttt ttaagaaatt ttctaatttg cctgaaaacg ttctcgtatt
    10021 ggttggcttc agtatgtcaa aaggatttac agcttatggt atgagaatgg gggctataat
    10081 ttgtatatct tcaagtgaag atgtagctga agagttccat tattcatgtg ttcattcatg
    10141 cagagcaaat tggtcaaatt gtaatagaag tgccatggca gtattatcta acattgtaaa
    10201 tgaccctaaa aaattcaaag aatatgagga tgaaaaagaa atatacaaaa acatgcttac
    10261 tagaagagca gatgtatttg taaaagaagc tgaaagagta ggattagaaa ttcttccata
    10321 tatagcaggt ttctttgtaa gtataccatg tgataatcca aaagaagtat gtgaagaatt
    10381 aactaaacat aatttatttg cagttccatt aaaaatggga ttgagatttg cagtttgtgc
    10441 agtttctgaa gataaatgta agaaagcacc aagtattata aaagaagcac ttgaaagttt
    10501 agaagtaaaa ataaatagtt aatttcattg aacaaattgg gtggactatg aatttaataa
    10561 ttgtagatgg agggaatttt atatgaaaca attgatgaca ggtaatgaag caattgcacg
    10621 tggagcctat gaagctggtg ttaaatatgc atctgcatat ccagggactc caagtacaga
    10681 aatattagaa aatatagcaa catataaaga tgcaatagtt gctgaatggg ctccaaacga
    10741 aaaagtagca cttgaggctg ctataggggg ttcaattgca ggagcgagaa caatggcttc
    10801 tatgaaacat gttggcttga atgttgcagc tgatccaata tttacttatg catatacagg
    10861 agtaaatggt ggtatggtac ttattacagc agatgaaccg ggaatgcatt catctcaaaa
    10921 tgagcaagac aataggatgt atgcaaaatt tgcaaagata cctttatttg aaccatcaac
    10981 tagtcaagaa gctaaagata tgataaaaga agcttttgaa gttagtgaaa aatacgatac
    11041 accagtttta tatagagtta caacaagact ctgtcattca aagggattag tggagtgcta
    11101 tgatagagaa gaagttgaaa ttaaagatta tgttaaaaat gctaagaaaa tggtaactgt
    11161 tccagcaaat gctcaaataa gaagaggcgt tgttgaagaa agaatggaaa cacttaaaaa
    11221 attctcaaat gaaactgatt taaactacta tgaaataaat gatacaaaaa taggtgttat
    11281 agcttctggt atgtgttgta attttgccaa agaagtcttt gggaaaaatg catcatatat
    11341 gaagctagga ttcacaaatc cattacctta tgaaaaaata aaagaatttg cagagaaagt
    11401 tgataaaatc tatgttatag aagaaaatga cccatttata gaagaacaaa taaaagcata
    11461 tggaatagat tgtattggaa aagatgtaat accaccatat ggagaaatga caccagatgt
    11521 tttaagaaaa gctatatttg gaaaaacaag tgatactata gaatacaaat ctgaattagt
    11581 aacaccaaga ccaccaagtt tctgtgcagg atgtccacat agaggatttt tctatgaact
    11641 tggaaagaga aaaaatttaa tagttggtgg agatataggt tgttatactc ttggatttgc
    11701 tcctccatat aatggaatag attatgttgt ttgtatgggt tctgcttttg gaactgcaca
    11761 tggagctcaa aaagttctta atatgaagga taataatgaa aaaagattag taggtgtact
    11821 tggcgattca acattcttcc atacaggaat aaatgggctt ttagatgttg tttacaatag
    11881 aggaaattct atttcagtta tattagataa tagaataact ggaatgacag gtcaccaaga
    11941 aaatccaggt tcaggatata ctttacaagg tgctaaaact aaagaagttg atatagaagg
    12001 attagttaaa gcttgtggaa tagaacatgt aagagttata aaccctaata atttaaaaga
    12061 agtaaatgaa gcgctagatt gggctttagc tatagaagat gaaccatcag taataataac
    12121 aagatggcca tgtgtactta aaaaattctc taaagaggat atagaggaat ttaataatcc
    12181 atttaagact aagtgtaaag ttgaccatga taaatgtata ggatgtaaat tatgtttgaa
    12241 aactggatgt ccagcactat catttgataa agagaataag ttatcaaata tagatagaaa
    12301 ccagtgtgta ggatgtggag tatgtgcaca agtttgtcca aaacaagcaa tagttaagga
    12361 ggaaaaataa tatgactaag agtatacttt tggtaggtgt aggaggtcaa ggaactatac
    12421 ttgctagtaa attattaact atgggattga tggaagctgg atacgatgta aaaatgagtg
    12481 aaatacatgg aatgagtcaa agaggaggtt cagtttcctc acaagttaga tatggagatt
    12541 gtgttcattc tccagttata gaaattggtg gagcagatat attagtatct tttgaaaaaa
    12601 tggaagcttt aagatggttc aattatctaa aaccagaagg aaaagcttta gtaaataatc
    12661 ataggataga ttctatgact gttttaatcg gaggagctga gtatcaagaa agtgatatag
    12721 atgcggagtt aaatagatta aatgcaaaag ttataaatgc agctgataaa gctgaagaac
    12781 taggaaattc aaaaataatg aatgttattt tattaggatg tctagttaaa tctatgcaat
    12841 tagagtctat tgactgggaa aaaattataa gtgaaaatgt taagccaaaa tttgttgaat
    12901 taaacataaa agctttccat gaaggtatgg aaatggttag caaatagttt ataatagata
    12961 taaatagact atagaaatta aggtgaaagg aagaaaatta tgacttacag aatattagcc
    13021 ataaatccag gttctacttc tacaaaaata gcagtatatg atggagaaga acaaattctt
    13081 gtgaagacga tagaccatcc agctgaagag attgcaaaat ataatactat acaagaccag
    13141 tttgaaatgc gtaaggaagc agttttgaat attcttaaag aaaatagtat agatttaaaa
    13201 tctcttagtg caatagtagg aagaggtgga gttttaccac cagtaaaatc aggagcatat
    13261 ttagtaaatg aagaaatgat tgatgtactt agacatagac cagtgcttga acacgcttcc
    13321 aacttaggtg ctgttgtagc acatgcaata tcagaacctc ttggaataaa ttcatatatt
    13381 tatgattctg ttgcagtaga tgagcttata gatgtagcga gaatatctgg gctttgtgga
    13441 atggatagat caagtgcagg gcatgcatta aatactagag caatggcttt aaaatatgct
    13501 aaggataatg gaaaagatta taagagctta aatttaatag tagctcatat tggtggagga
    13561 gtaagtattt atcttcatga aaaaggaaga atggttgata tgttatctga tgatgaagga
    13621 ccattttctc cagaaaggtc aggaagagta cctgccacaa aattagtggc tgcctgttat
    13681 tcaggtaaat actcagaaag agaaatgact aaaaagataa gaggtaaagg tggtatagtt
    13741 tcatacctaa atactgtaga tgctagagaa gttgaaaaaa tgatagcaga aggaaatgaa
    13801 gaagcaaaaa ttatttatga agcaatggct tatcagttag caaaaggtat tggagagtta
    13861 gcaactgtag tagatggaaa tgtagatgct ataattataa caggtggaat tgcatattct
    13921 gaaatgttta cttcaatggt taaaaagaaa gttgagttta tagcacctgt agaaattatg
    13981 gcgggagaaa atgagttgga atcacttgct tttggaactt taagagtact aaatggagaa
    14041 gaagaagcta gaatttatag tgaaaattaa taagaaaaac taaaaatgtt tatatactaa
    14101 aaaagtggta tatccgtttt ttatacacga aagcttagag tataggtgaa aatgtataaa
    14161 gtttggattg ccacttttta taattaaaat tttatcttaa gctaataaat aattctgtaa
    14221 aatttcgtat ttatatatat tttattggta tttattgtta ttattattat gaggagtgat
    14281 ttttgatggg aaaaatgaat ttaaaaagta tggcaagatt attttcaggt ttttttatat
    14341 ttgcaatttc ttctgtgctt atgattaatg cacatgtagg tcttatgcct tgggatgtac
    14401 ttcatcaagg tttatctata aagctaggta taactatagg tcaggcttct ataatggtag
    14461 gagtcataat tgttatattg gatgcagttt ttggtgaaaa tataggatgg ggtactttac
    14521 tcaacatgac gtttatagga atttttattg atttagtaat attttctgga gtgatacctc
    14581 atgcaagtaa cacttatata ggtgtgctta tggttgttat aggaattatt ttggcagcta
    14641 tagcaagctt tctatattta ggtgtttgtc taggaagtgg accgagagat gggcttatga
    14701 ttgctcttca gaaaaaaact aataaatctg tacgtcttgt tagaacaatt cttgaaatac
    14761 tagcattggt tgttggttgg ttattaggag gttctgtagg tattggtact cttgtaagtg
    14821 ctttaggttt aggatatgta ttacaaatag tgtttagaat atttaaattt gatacaaaat
    14881 tactaaaaca tagatttatt atagatgata taagagaatg gaaggaaaag aaaagtgatg
    14941 aacataaatg taaatcaagt attgtaataa aaaatgagca gaattaatta tgctaaaata
    15001 tatttatagt ttatcaaagt tatagtaaag gcaaggagac tttgaaatgg aattatggga
    15061 tttatataat gctgatggaa ttaaaacagg aaatgttata aaaagaggta attctattga
    15121 agatggttat taccatttgg cagttgaagt gtggatttta aatagtaact ctcaaatttt
    15181 aattcagaaa aggtctaaaa gtaaaaagac attgccaaat atgtggggaa tgacaacggg
    15241 gtgtattgtt tctggggaag agagtttaga aggagcaatt cgtgaagcaa aggaagaaat
    15301 agggatagat ataactaaag atgagatgaa gatttttaga agtatgactc atgaagatac
    15361 cctttgggat gtatatttgg tgaaaaagga atatgatata tccaaagcca ttttacagga
    15421 ggaagaagta agtgatataa agtgggtaag cacagatgaa ataagacaat tactaaaaga
    15481 aggtttattt tttgaatatc cagagatata cgaattgcta tctgagatag ataataataa
    15541 attaaatata tgatgtagag cagatttcag tataagtatg attaaaaatt tatcttctct
    15601 aaattttaat attgttttat gaaaattaat aagttatttt tagtattttt ctacttgttt
    15661 tttaagatta aaataaaaaa gggcggtcat tgtaaagtca taaaaatttg gggaggcttt
    15721 aaactatgga agataacaaa ggattggcac acgacagttc aaagtataaa attgtttcta
    15781 tatctgttgt agtaattatt ctaattacat tttggtatat gttaaatatg gtgcttttaa
    15841 cattcattat gacttttatt ttctataact tgcttgtagc cacaagaaaa cgaattaaga
    15901 aattttctta tttaaatatt ccagattcat tgataattat agtgttatat gcactatttg
    15961 ccatgttgtt ggtattaatt agttatgcag ttgtaccaat aattatagtt caacttacag
    16021 agttgagtag ggtttttagt gattttgatg taaatcaatt tgctcaatct ttaggaccaa
    16081 aactgtatcc tattgtttca aagctagatt ttaataaata tatttcacaa gcagggctac
    16141 tcatagcatc aacagcgaca aaagttggaa gttttggagt aaatatatta ttagcttttt
    16201 tgttgagttt acttctttta cttgaaaaaa atgaaattaa aaagtttgga gataaacttt
    16261 ctgatagtaa gatttctttt atttataatt cgcttgtatt ttttggaaag agttttgtta
    16321 aaaattttgg tgaagtaatg aaagtgcaag tgatgattgc ctttataaat tctgttgttt
    16381 ctatgatttt tttaggtttc atgagattcc ctcaaatatg ggccttagga tttatgattt
    16441 ttgtgttagg tcttattcca gtagcaggag ttattgtgtc tttgattcca ttaactgtaa
    16501 tagcatttaa tacaggagga ataacaaagg tttttggagt tttacttatg atttgtatag
    16561 tgcatgcaat agaaacatac atattgaacc ctaagttgat gtcaaataga actaaacttc
    16621 cagtttgttt tgtttttatc attttacttg taggagaaca ctacttaggt gtatggggat
    16681 tactaattgg agttccaata tttatgtttc ttatggatat tctaggtgtt aaatttactt
    16741 ctagataata tattaaaata ataatttatt tttatatata ttatgaattg ttttaaaaaa
    16801 gaacctataa atagacatca ttaataaaga tatctatttg ataggttcaa ttttgatttt
    16861 tataaatact ataaacttaa atgaaaagaa atttatttca tttcaaaagt ttcacaactt
    16921 gcattttttt catttatatg aactttttca gctttgcaaa gttcattttt attgtattta
    16981 cattttacag cttcacaatg aatgttatct gtatcaactt ggttagtttc attagaacga
    17041 ctagttattc cagatgtata tttgtcttca aaagaagcac aataagtatt ttctgtagta
    17101 gttgcttgca ttccatctac ttttatacta ccagcataac agtatccact agtattataa
    17161 gcacaattag tagcagcaca atttaaatta ttatttttca taaataacct cctaagtttt
    17221 atttaaactt attatgtgaa gttatctaaa ttttatacac ttatttacaa atacatttat
    17281 tacatttaac aactacatct ttggaagttt ctcttcctaa atttttatta acatgatata
    17341 catcaacgtt ttcagttgaa ccacatatag aacatgtaaa attattttct agtagagttc
    17401 tttctttaaa taacttccaa tacatagaat tgatgtaatc attataattt accttgaggc
    17461 atgtctcaag gaagtttatg tatagattgt ctaaatctcc tgtatttaac tctgtatatt
    17521 ctggttcaaa atattcacaa catcctctaa aatcaggctt tgtatctgaa ataacacatt
    17581 taatatcata tctatagtct aggctaggcc ccttaaatga aagatgtgtg caaaaagaac
    17641 aagatgtttc tggtagattt ttttcaagtt catgtaattt attattcata agtattcctc
    17701 caaaaaattt attttaagta taaatgaata gattatttta aaacttttat ttatttatat
    17761 tagaaatata ggataaatat tccaataagg agtaaatact taaatgttta tttctgtatt
    17821 aaataaaaaa gaggcaaatc taacttgaga ttgcctactt ttttattact ttttaataaa
    17881 atttaatcta aatattattt tatttacctt tagtcagcta atttagtatc tgctctgctt
    17941 tttaactttc taccagagtg tacagttaaa atagcatata atacagtaaa tatggcagct
    18001 aaaacgtatg atatattcat gtttaagtta aatccaattt gagcattaaa tatataacta
    18061 aatataacaa aagaataaaa catacctgga attaagctta taatataatt cttttctttt
    18121 actataaggt aaactgtaat cattgcaaac gcaaatatgg cgatagtttg attactccaa
    18181 gagaagtatc tccacaatat attaaatcca gaggcactaa gttttgcaaa tataagaatg
    18241 gctatgacag gaataaatat acagattgat aatataacac gatgtttctt ttccttttgg
    18301 tcataatgaa agtaatctgc aagcattaat cttaaagatc ttaaagctgt atctccagaa
    18361 gttattggta aaacaattac acctattata gctatgatac caccaataga gccaagtaaa
    18421 tctcttgcaa ctaaacctat tacatcagga gaacctatta attccttagg tattccttta
    18481 ttgtagatac ccatagcagc agcagcccaa atcattgcaa ttagaccttc taaaatcatc
    18541 atattataaa aagtagtctt tccttctttt tcatttgaaa ctgatcttgc tataagagta
    18601 gcttgagttg agtggaatcc agaaacgata ccacaagcaa ctgtaacaaa gaatgtagga
    18661 ataagaggaa tcccatcagg atgaatacct ttccaatttg caagacttaa attagccaaa
    18721 tcataacctt gtgtaaagat tccaactcca acaccagcag cagataaaag taggatagct
    18781 ccaaatattg gatatatctt tcctatgatt ttatcaattg ggaatagtgt tgcacataag
    18841 taatatagaa agataattcc atagactatc cagacaactg gattatttat agtcgatttc
    18901 atatttaaaa tttgagtaac aactaaatct ccaggtgtat aaataaaaac tgcaccgact
    18961 aaaagcatta aaagacaaag gaatatatta tagacttgaa atactttatt acctaaaaat
    19021 ctacttataa gagaaggcat ttgtgctcct ttttctctta tactaatcat tccactcata
    19081 tagtcatgta aagctcctcc aaatacacag ccaataggta ttagtatgaa tgctattgga
    19141 ccaaacaata taccttgtat aggtcctaga attggtcctg taccagctat attaagcaac
    19201 tcaattagac tatttttcca ttttttcatt ggaacatagt ctactccatc actttgagca
    19261 agtgcaggtg tttttctgtc atctgggcca aatacttttt cacaataagc accgtataaa
    19321 gcacctccta ttagtaatat agccaagccg attaagaatg ttgtcataat atcaccccat
    19381 ttataaaatt ttttggtctt tgtatacata ttatctaaat gtgtagattt atatgacatt
    19441 taattctgga caacctacaa attctataaa gtattaaaac taatataatt tcagaaataa
    19501 atacatatac ataaccatgt acttagtata caggtatttg atattatttt caatattata
    19561 tcaataaaga atataaacaa aattctgata atattttaca aaaaaattaa aaaatataaa
    19621 aaatagttta aatagatgag gaaaaaagga aaatgaattg atactgtaaa tgtctatatc
    19681 ttaacaatat taagaggttt aaaattcttg aagaaagaat agtcaagtga tataatgagt
    19741 ttacaggtgt atatacacta gtacatatag aaagcggtgc aattatggat aaagatttaa
    19801 catatcaaat caaagagcta aagaaagaaa aaaatgcaat aatacttgcc catttttatc
    19861 aaccaccaga gatacaagaa ttagcagatg cagttggtga ttcatattat ttaagtgaga
    19921 ttgctagaga ttgtaaagaa gaagtggttg tattttgtgg agtaaggttt atgggagaaa
    19981 gtgctaagat attatcacct gaaaaaacta tattgatgcc agtaagtaat gctgggtgtg
    20041 ctatggcaga tatggtagat gaagaaggcg tgataaaatt aaaacaacag tatccaaatg
    20101 ctttggttgt atgttatata aactctacag ctaaagttaa ggcacattgt gatgtttctg
    20161 ttacatcttc tagtgcaatt aaaatattag aaaacataga taataaagaa attatattcc
    20221 ttccagataa aaatttagga ggatatattg cagaacaatt tccagataaa aactttatat
    20281 tttgggacgg atattgtaaa taccacaaca atataagggc tgaagaaata attgagttaa
    20341 aagataagta taaaaatgca gaagtattag tacatccaga atgtaaaaaa gaaataagag
    20401 atttaggaga ttatgtaggt agtacatcag gaataataaa atatgctact aatagtaaaa
    20461 acaaagactt tataatagca actgaagaag gtatattaca tgaattaaag aaaaataatc
    20521 ctaataaaaa tttttatatc cctggtggaa aaatactatg tacagatatg aaaaagacaa
    20581 cattagaaaa tttatatatt acacttaaaa atatggaaaa tgaagttatt gtagaagatg
    20641 aaattatgga aaaggcttta aattcactgc ttaacatgca caaattagca gaaggataga
    20701 ggtatagact tatgaattta gaacaagatg ttttaatagt tggaagtgga gtttcaggat
    20761 tatattgtgc attaaattta gataaaagtt taaatgttct agtagtatca aaatcaacaa
    20821 ttgaaaacaa taatacatat cttgcacaag gtggaatttc aactgctaga aatattgatg
    20881 atatagaatc ctttgtagaa gatacaatga gggctgggca gtataaaaat agagttgaag
    20941 cagttcaagt acttgcagat gaatctatag aaaatgtagg gcagatagta gaatatggta
    21001 tgcctttaga taaagaaaat ggagagatag attacacaag agaaggagct catagtgtaa
    21061 atcgaatagt tcatagtaag gataatactg gagaagttgt ttttaaaact ttattaaaag
    21121 aagctaaaac tagagaaaat ataactctta tagaagatgc ttatctttta gatatactaa
    21181 aagatggtaa taaatgtata ggggctagaa tttttaaatc taaaaaagag attcatgttt
    21241 tttcaaaaat agtagtttta gctacaggtg gaattggtgg actttttaaa aattctacta
    21301 atcaaagaca tcttacaggt gatggaattg caatagcttt aagaaataat ataaaaatag
    21361 aaaatttaga atatattcaa atacatccta cagcttttta tgaagaaaat aatgaaggta
    21421 ggagaatgct tatatctgaa tcattaaggg gagagggagc taagctttta aataaaaata
    21481 aagaaagatt tgttgatgaa cttcttccta gagatgtagt ttcaaaagct atttttgaac
    21541 aaatggaaaa agataagtta ccttatgtgt atttagatgc aacacatcta gatagtgagt
    21601 atttaattaa tagattttct tttatatata atgaatgctt agctagagga acagatataa
    21661 cgaaagaatg tataaaggta tctcctgcac aacattattt tatgggcggt atacatgtag
    21721 atttggattc aaaaacatct atggaaaatt tgtatgcagt tggtgaaatt agttgtacag
    21781 gtgttcatgg agccaataga ttggcaagta attcattact tgaagggctt gtattttcaa
    21841 aaagggcagc taaaaatata aactcggtta tagataatgt aaaagttaag tttgtagata
    21901 taccagatat ggatatagat atagaacagg taaaaaaaga aaataaaata ttagtcataa
    21961 aagaaattga aagaacaagt gaggattttg gtgatgaatt atttgattat tgatagaatg
    22021 atacaagatg ctttgataga agatgttcca agtgaagata taacaacaaa ttctattgta
    22081 gatgaaaact ctaaatctac tgtagattta atttgtaaac aagatggtat aatagctggc
    22141 ttaggtgtat ttaagagagt ttttgagata cttggtaatg taggtgtaga attatataaa
    22201 aatgatggtg atagagtaga gaatcgtgaa aagatagctg tattaacagg tagtactaga
    22261 aatttacttg taggagagcg tgtagcattg aattatttac agagaatgag tggcatagct
    22321 actattacaa gtaagtatgt tgaaaagctt gaaggtacaa atacaaaatt attagatagt
    22381 agaaaaacga tacctaatct tagaatatta gataagtatt ctgttaaagt aggtggggga
    22441 tgtaatcaca gatttaattt atctgatgga atattgctta aagataacca cattggggct
    22501 gctggtggtg ttaagaatgc agttgaatta gctagaaaaa acacttcttt tgttagaaag
    22561 atagaagtag aagtagagac tttagacatg gtaaaagaag caatagaagc taaggcagat
    22621 ataataatgt tggataatat gagtttggaa atggcaaaac aagcagtaga tattataaat
    22681 ggaagagcaa ttatagaatt ttctggaaat gtaaatttag ataccataga agatatagga
    22741 aaaatcggtg tggatgttgt ttctgtagga gcacttacac attctgttaa agctctcgat
    22801 ataagtatga agaatttgag aaatatataa attttatatt gaaataaatt taattgaaat
    22861 agactcctta aatttgattt ataaatttaa ggagtctatt ttttattcat taaaattaat
    22921 aaaaatataa aaaaatcaat caataattta ataaaaatag ataaacacta tatacacttt
    22981 taataatata gttattatct attttacaga taaataagaa taaacttata atataattgt
    23041 atctgtaaaa ttttgtaaaa atataaaaag tatagggggg aataaaaatg aaagtagctt
    23101 atatttttag tagtactaat acacacaaaa ttctagacaa aatgataata ccacaacttg
    23161 aacaaggaac tcatggagta gatgttctag ggatgttttt ctttatggat aataccctat
    23221 ttttatctaa aggtaatcct ataggggaga gattaagtaa attacatgaa aaaactgata
    23281 tgataataat ggcttgtgac caatgtgcta tagaaagagg tatagagaat aatttggttg
    23341 atggagctac aattggatgt ttcccaaacc tatatgcttg tttaggcagt gcaggtgtgg
    23401 accaagttat aacgttataa attagtgtag gatacaatcc atagaaaaat ttattttctg
    23461 tggattattt taagtaaaag ataaattgtt taaagtaggg gatgagcaaa tgtctaaaat
    23521 tttagttgaa tttataaaca cttgaccatc ttgtgatgag catggagtgt ttataaaaaa
    23581 aatgtcagaa aagtatgctg ataaattgga aataaaatta tatcaagcag gcaaagattt
    23641 ttcatatata aaaaaatatg ggattgtaac aaaaggaact ttaataataa atcagaaaaa
    23701 gaaatatgat agattaaata aagacacaat tgaaagggca atagtagaag ctataaacaa
    23761 taattaaaag tttaaaaatt aggagtatca aaaaatgaat atattagaaa ttgttttaaa
    23821 tggagttaaa gatactatag tagcttccat agttacatta aatggagcat caggatggct
    23881 tatgataagt tttatattag caggagtgct tcacaatgtt ttaactccta gaagatttca
    23941 aaaacaactt ggaaataaga aattttcctc tttgattaaa agtactatct caggaatgtt
    24001 tttaccaata tgtagttgtg gggtaatacc acttggaata agcatgtatt attcaggggc
    24061 atatttagga ccggtacttg cttttatgac atcaactcca ataataaatc caatagctgt
    24121 agttctttgt ctgggtcttt tagggtccaa agttacaatt atttatctaa tatctggttt
    24181 tttagtacca tttttagtag gatttttagg aaattgtttt ggaaaagaag aattatcact
    24241 tcataatgat ttagaggaag aagtaataga attagaagaa gaaaaaagaa gttttatgga
    24301 aaatatgatt gatggtctta aatggtcttt cggggagttg gctcttacta ttagtaaata
    24361 tgtagtaatg ggtatggttt ttgcaggatt tataacaacc atttttccaa atagtataat
    24421 tcaaaaatat ttaggaaatc caggtttgtt atctcttgga agtatagcaa tacttgcatg
    24481 tgttatgtat gtatgtgctg taggacatat accgtttata gcagccattg ttgcaagtgg
    24541 agcatctcct gggatagcta taacatttct aatagctgga gcagctacaa atctaccaga
    24601 acttataagt atgtttaaac ttattggaaa aagaactgtt attatatatt ctgtaacttt
    24661 gacactgtct tcaataataa ttggatatat aacaaattta cttttagtga acaataactc
    24721 agtaaattta gatgcaacaa attcttcaat acagttggca aataaactaa tgttaaatat
    24781 acctgatagt tttgagtatg tatgtacgat tttaattatt ttatttgcat ttaaatcaat
    24841 aataccaaag atgaaagagg tcataggaaa tcatgcttaa aaagatagtt ataatatcct
    24901 gtatagtagt tgtgttaatc attttatcaa aaatagttga tgataacatc aaagaagatg
    24961 cctctattcc aaatgtgaat aaagaaacat tagaatattt tagaaaaaat tataaagaag
    25021 acataataac ttgtgctgaa gaagacttaa ataatgatgg gaaaaaagat ttagtagtta
    25081 tatataaaaa aagcaataat tcaaatgaaa tggtagttgt ggtttctgat aaaaatagcc
    25141 attatataac aaagccaata ccagcaccta tagagaatca aactataacc tttaaaaata
    25201 ttgatgataa agcaccaata gaagtaatag tatcagggtc taaaaatggt aatgtaggat
    25261 atgctattta cagagtagag ggtaagaaat ttgttgattt atttggcgaa gatatggaca
    25321 aatgttgcta aaaataatac ataaaggtgg gaaatttata tgaaattatc taagaagatt
    25381 caagcattaa tcttatttgg tgtaatgggt acatctatat taacaggatg tagtagtaaa
    25441 caaaaagaag aagcaaaagc tggaaaggat gattatacaa taacagtagg ttattataat
    25501 tgtgaccata tgactgcggg accagtagca gaatcagcag gaatatataa agatttaggt
    25561 cttaatgtaa aaactgttgg aaatggtaaa gttcctgaag ctatggcagc aggaaaaatg
    25621 gatgcaggtt acataggaac taaaggttta gttggagcaa tacctaaggg ttcaccaata
    25681 acaatagcag ctaacaacca tactggtggt tctgaatatt taatagtttc aaaagatata
    25741 aaagaaccta aagatttaat tggtaaaaaa attgcaacag atatgagtga tttcttatgg
    25801 acaagtgatt atggtccaga aacaggttta ccaactgacc catcaaaata tgaagttgta
    25861 aatatggatt cagacaaaga taaatattta gctcttaaaa ctgggaaaat tcaagctttt
    25921 acatcttgtg acccttgggg ttctgtagct gaaaatgacg gtgcaggaaa aataatagca
    25981 tctactcaat ataaagaaaa agctaatggc aaagaatata actgttgttc attctcattg
    26041 aacaaaaact ttataaaaga acatccagat ttagcaaaaa aattggttct agcacataca
    26101 aaagcaatag aatatatata tacaaatcca gctgaagcag ctaaaatatt tgcaaaatat
    26161 tataatgtag aagaagaagt tgcacttaga actatctata agaagactgt tggagaaggt
    26221 agaactctta cttggaaagt tacaggtgaa gaatataaaa acaatttaca aatgtataaa
    26281 gatttaaagg ctttagatga tatacctaaa tatgaagata cgattgatac aagcttatta
    26341 gactcttgtg gagctgatga ttttgacaaa tttataaaag aaaaagttaa cccagagttt
    26401 cctgaaggta tgagttatga agattggaaa gcaaaggtat tataaataaa tggagaatat
    26461 aaaaaatata ataatacttt ttatcattat tttaggaagt atatttataa tattttttaa
    26521 ttttgaagat aaagaagaaa taaaaggaaa actaagaata ggggtatctg atgatacctc
    26581 tggttttgta ataaattata tggtaaatag agactacttt gaaaatataa aagtaagtga
    26641 tataatggat atttttacaa ttaatgattg ctgagcaagt acaatgcagt gggctctgag
    26701 ttcagaggaa atagatatag caatcatatg taaagatgct gcaaaacaat atgtaaatgt
    26761 aaatagtgga tttgaaattg ttggtactgt agttcaaaat tctgatatat ttctattaag
    26821 tgataataat cctaaaaaga tgggagtcat tcaaaataga gattaccagt cagaattggt
    26881 taaaaaatac tacaagaatg tggaagtagc tcccttatta gggactgcac ttgcatatgg
    26941 attagaaagt aatttagtag acggtgttgt aatagattgc ataaagtcaa ttgggttaga
    27001 gggtaaaaga aaatctacaa ctaaattagg agattatgat acctatgtat tagttgtaag
    27061 taaagagttt aaaaaaagta aagcatatag tgattttata acactttaca ataaaagtgt
    27121 tgatgcttta aagaataaag ctacatttaa gaaagcatta aaagagtaca ggaatataag
    27181 aaatatagat atggaggaaa taagcaattg gaaattaaaa tttctaaaga taaaagcgat
    27241 agattaacta agaaaaaaac tgatggtagt atggatattt tatataaaat aatactatta
    27301 gttattatat ttttagtctg gcattttgca gcaaaagata tagggagttc tttattactt
    27361 ccaatgccag tagatgtaat aaaaggtttc tttttctgtg tgacagatgc agagacagtt
    27421 actaatcttt ttataacatt gcagagagta cttaaaggtt ttatctatgc attattgttt
    27481 gggcttccaa taggatttat tatgggattt tctaaaacct ttgaaagggt tttatctcca
    27541 gtagtagatt ctgtaagaca agttccaata atggcatggg ttcctcttac tatagtgtgg
    27601 tttggtatag gagatggtcc aacaatattt ttaatagctt tttcaggggt cttccctata
    27661 attttaaata ctattcaagg agtaagagca atatcaaagg attattataa tgcagctaga
    27721 agtatgggag catcaccaat tgtgatattt acaaatgtaa ttattccagc atctcttcca
    27781 gatatactaa ctggttcaag aattgctata agtacaggat ggatgtctgt tatctgagcc
    27841 gagtttatag ctacgagtgc cggtctcggt tactcaatgg tacaagctca aacattaatg
    27901 catacagatg tattaattgg gcttatgata tttgcagctt taatagggtt tataatagat
    27961 agggtattaa agtttataaa taaaatcctt tgtagatgga ggtttgcaga ttaatgaagt
    28021 taagtgtaag agatataaat aagacatttg taaataatag agtaaataca aaagttttag
    28081 aagatataag tatggatata gatgatggac aatttgtctg tcttttagga ccatcaggtt
    28141 gtggaaaaac aactttactt actataatag gtggatttca aaaatcagaa agtggagatg
    28201 tttttataaa tgataaaaaa gttaaaaaac caggaataga tagagctttt atatttcaaa
    28261 attatgcttt atttccttgg aaaactataa gaggcaatgt tctatttcct atgaaacagc
    28321 agaaaatacc aaaagaaaaa agagaagaaa tgctagaaga acttttggtt atgtcagact
    28381 tgaaaggaaa ggaaaaactg tttccacatc aattatctgg aggaatgaaa caaagagtgg
    28441 ccatgataag agctttagca tgtaatccag agatattact aatggatgaa ccattagggg
    28501 ctgtagattt tcaaatgaga caaaatttac aggaagagct agaacgaata tggataaaga
    28561 agaaaataac tgcattaatg gtaactcatg atgttgatga agctgtatat atgagtgata
    28621 gagttatagt aatgtcgaga gataaaggaa gaattattga tgatataaat atagatattc
    28681 caagacctag aattagagga agccaaaaat atgaagagta caaaaacaaa ttaactgata
    28741 ctttatcaaa gtgttatgaa gtttaaagag gagtagacat gagtcaaata gaaaaataca
    28801 atagtttgga taatacacaa cagaaaataa gaatctctat tatggatatg ataatagata
    28861 aaggttctag tgttacactt caagaagtga ctgaatatat aagtaaaaag ttgaatatgg
    28921 aaaaagaata tatagaaagt acactacaat attttattga taaaaatata atggttgttg
    28981 atggagatag tataaatttt atatatcctg tatcagcatt gccaacaaat cataaagtaa
    29041 ctttgagaga taatagaagt tttagtgcaa tgtgtgctat agatgctata gggacatctt
    29101 gtacctttaa ccaagatgta agaataaact ctatttgtag tgttacaggt agagagatag
    29161 aaatagttat aaaaaatgaa aagattgagt atgtgaataa tccgagctta agggtgcttc
    29221 atataaatct tgataagtat tcaaattggg ctgctaattg ttgaaatata atgaatttct
    29281 tctggacgaa gagtgatttt gatgcttgga caatcgaagc tgggttatct gatgacgaag
    29341 atatatattg tttagatatt aatgaggcaa tagtagaatc gtataaaata tttaaactca
    29401 aacaaaagat aatattgtag atatacataa aaaactaaaa attaccttta ggtaaaaatg
    29461 atagataata tccatactgt ataaattagt atagagtatg gatatgaaaa gtatttaaat
    29521 ctaaaggtat atttttagtt tttttatatg attagatagc cttattaagt atatatttat
    29581 ttataacctt tgcaactcca ttttcattat tagtatcagt aacataatct gcaatttcct
    29641 ttatactatt acgtgcattt cccatagcca caccaagacc tgcatacttt atcatatgtt
    29701 ggtcattttc ttcatcgcca acagcaatag cattttctat aggtatgttt agattagcac
    29761 ataatgtttt aagtgcagtt cctttattag tagttttacc taaaaattct agataaaaag
    29821 gagcagacct tactatagta tatttattga ataaattttt aggtagctgt tgtatgattt
    29881 cttccaattt ttctggttca tcaactatca taattttaca gattttaata gattcatcaa
    29941 ttttatcttt ttgtatatat ttgacttcta tatcatttaa tttcgcttca tgaagtgtat
    30001 attttccagg agtttcattt ggtgtaatta aatttgtcat tgtatttatg tgtattttag
    30061 tcttatattt tttacaaacg ttattatata taaaatcaaa atcatctaaa gtcatttcta
    30121 catcatgtat aattttctca cttttaacct cctgaataat tgctccatta aagcatataa
    30181 cataatcccc ttcatctgtt aaatttagtt gatttagaag ctcttttaca ccaggaagag
    30241 gtctgcctgt tgttataact acttttgccc cagccctttt tgcctcttga atggactcaa
    30301 agacttcagg agtaatcctt ttttgtgtat ttaatattgt tccatcaatg tctagtgcga
    30361 ttaatttgta catatcaacc tccaataaat tatatactca aatttcctgt gaaaacgttg
    30421 gcacgactag ttttgaacaa agtttcagtg ggaaatatgg tttgttttgt atactattat
    30481 atcaagagat aagtaattta gaaagtttaa taatattaat tttttgataa aaatattacc
    30541 tatgtgagat gagagtgtaa aaactttgta atcaataatt ccaaaatttt taattacaaa
    30601 taatggtatc gtttgcattg ttaatataaa tataatgtat attatatagt tagaagtttg
    30661 aataaataga ctgatggtaa tttgttatat tagttagttt tgtgttataa aatattgtaa
    30721 ttccattaat catatgttat tattcaacat gattgcaata taaagaatat ttaatatata
    30781 taataattta taaaagagta ttacatagta catgtaaagt tatatttata aatacaataa
    30841 aataaagttg taaaggagtg ttttaaatga agttttcaga gtttaagtat gaaagaccca
    30901 attataatag tatgaaaaaa gagtttttgg gttgtgtaga agatataaat aattctcata
    30961 attataaaga gcaacaaaaa aatatacata agcttaattt attgagaaat aaaatagaaa
    31021 cgttgtcaaa tatagcattg ataagatata gcacagacac acttaataaa ttctaccaag
    31081 aagaaaaaga ttattgggat gaatatatgc ctttatatga agaattaaat tcacattttt
    31141 ataatgctat tgtaaattca aagtttaaat gtgatttgat aaaagagttt ggagaacaat
    31201 ttttcacaat agtagagtat tctttaaaaa gtttttctaa agaaataata agtgaattac
    31261 aggaagaaaa taaattgtgt tcagagtata ctagactttt agcctcagct gagataatgt
    31321 ttgatgggaa aataagaaat ttatctggta tggggaaatt tatgtattct aagaatagaa
    31381 aaataagaga actagcaaac aaagcatatt ataatttctt tgaaaaaaat gaaactaaat
    31441 ttgatgacat atttgataaa ctggttaaac ttagagataa gatatctaaa aaacttggtt
    31501 ttgaagattt tgtagagctt ggatacatta gaatgatgag aagtgattac agagaagata
    31561 tgataaaaag tgttagaaaa caagtattaa aatatgtggt tccaatggct aatgagcttt
    31621 atgaaaaaca agctaaaaga attggtctag aatatttaag ttatattgat gaaggtgtgg
    31681 aatttttaac aggaaatgca agcttaaaag gagattcaag atacataatt caaaatggaa
    31741 aaaggatgta ttctgaattg tcaaaagaga cgaatgaatt ttttaatttt atgttagaaa
    31801 atgagcttat ggatttagaa acgaagaaag gaaaaggagc cggagggtat tgtacttata
    31861 taccagatta caagtcacca ttcatttttt ctaattttaa tcaaactgct gatgatatag
    31921 atgttttaac acatgaggca ggacatgcat ttcagttgta tatgtctaga tggattgata
    31981 tgccagaaat taattttcca acgcttgaca gttgtgaaat ccattcaatg agtatggaat
    32041 ttataacatg gccatggatg gacttatttt ttaaagaaga tacagataag tacaaattta
    32101 ctcacttatc atctgcaatt aaatttatac cttatggagt aattgttgat gaatttcaac
    32161 actatattta caaaaatcct aatatagata agtcaaagag aaaagaaatc tggaggtttt
    32221 tagagaaaaa atacttacct catagaaaat atggtgataa ttctttttta gataggggct
    32281 gttggtggtt taaacaagga catatattta aaaatccgtt ttattatata gattatgtat
    32341 tagctcaaat ttgtgcgtta caattttgga aaaaaatgat tcaagataga gatacaggat
    32401 ggaaggatta tataaatatc tgtaaagttg gaggaacaaa atcattttta gatattgtga
    32461 gtatgggaaa tttgtattct ccatttgatg atggatgtat tgagtctatt ataggtgatg
    32521 ttaaatcttg gtttgatgaa ataaatgaca gcaaattata aaaaattatg agaattttat
    32581 tgtataaaat taaaaaatta aaaaatatat aaaaaacgat tatttgttgt gaaaatagtc
    32641 ttgtttttaa ctaaattgat aaaataaact aaaaaagatt tgcacttaaa aaaaaaagaa
    32701 aatacaagaa atatgcaata tcaacatttg gaaaaaaaag taaaaatgta tacaaaatac
    32761 atataaaaaa actattgcaa attttataga atgtttatat acttaagtca acagagatag
    32821 aaaaaagcta tttatagaaa acaaaggata aattgcttaa ttttaaattt tctgaaaaaa
    32881 ataataatcc ggatgaagag tatgggagac tgctttataa aaagcgaccg aagggacaag
    32941 tttaatctta cttacccaaa agattagatg aaattctcag gtaaaggtga ctgtacttgg
    33001 acggggctct gaaaatgatt ttaacaggga aggcaaattg ggagatttgt ttttcctgtt
    33061 ttttatttat caagaaataa ataaaagttt gaaagagagt aaaaaaatga taataattac
    33121 gaataatcca aaagtaaaag aagaagttca agacagagaa gttttgttta aagacacaac
    33181 ttatattgga atcttagaag caagtagaga cttgatacat gaaggttatg aacttttatc
    33241 tcatccactc tatgggagtg taaaaccaaa tgaaacacct tacaggactg ttgtactaaa
    33301 gaaaggaaat cgtttggata taaactcttt aaccttaatt gaagaagcaa tcatcactgc
    33361 aagtaaattt cagaataata aaaagactcc aaaatggaca gaaagtgttc aagatgattt
    33421 tagagtaatt gattatgata tattttataa tacaatacaa agaatgcagt atgaataaag
    33481 aaaattgtta aaaagttatt aaaacagcct aaatattaaa tctaatttaa tattaaataa
    33541 aatgagaaat ttaattgggg aggataagtc aaaatggaaa atgtgtatga cttagtaata
    33601 attggttcag gaccagcagg gcttgcagca ggtctttatg gagcaagagc aaagttaaaa
    33661 actctaatcc tagaaaaaga caagactggt ggacaaattg taataacaca tgaaattgca
    33721 aattatccag ggtcagttcc aaatgcaaca ggaccaagtt taatagctag aatggttgaa
    33781 cagtgtaaag agtttggagc agaaatgcta agagacaaca ttgttgatac tgagctagat
    33841 ggagatataa aagttttaaa aggggaaaag gcagaatata gagcaaaagc agtaataatt
    33901 ggtacaggag caacaccaag aaagattggt tgtcctggag aaaaagaact tactggtaaa
    33961 ggggtttcat attgtgcaac ttgtgatgca gatttctttg aagattttga agtatttgtt
    34021 gtaggtggag gagatagtgc attagaagaa gcaatgtatt taactaaatt tgctagaaaa
    34081 gtaacaattg tacatagaag acaaggattt agatgtgcta agagtgttga agaaaaagca
    34141 aaagctaatc caaagataga gtttttatta gatacagtaa ttgaagaaat caaaggtgat
    34201 ggaatattag aatcagttgt atttaaaaat aaagttactg gagaaacaca tgaatacttt
    34261 gcagatgaag aagatggaac aatgggagta tttgttttcg ttggattaga tgctcaaact
    34321 gatttattca aaggcaaagt tgatatggat gaaaaaggtt acataataac tgatgaagat
    34381 atgagaacta atataccagg ggtatttgca gcaggagatt gtagatctaa gactctaaga
    34441 caggttgtaa ctgcaactaa tgatggggca attgcatcta tagtagcaga gaaatatatt
    34501 gatgaaaaat ttggaaacta atatcaaatt tggaaactaa tatctgtaaa ttaaatttaa
    34561 tgaacaatat taaaataaaa taaaaatttc aaggaggaat aagagaatgt tagatttaga
    34621 taaggctaca tttgaagaag aagttttaaa tgcagaaggt tttgtatttg ttgatttttg
    34681 gagtgaaggt tgtgagcctt gtaaagcttt aatgccagat gttcataaat tagctgagac
    34741 ttatggagat aaaataaaat tctgtaagat ggatacaaca aaagctagaa gattagctat
    34801 aaaacaaaaa gtattaggtc ttccaactat ggctatatac aaagatggag aaaaagtaga
    34861 cgaagttact aaggatgatg ctacagttcc taatatagaa aacatgatta aaaaatatct
    34921 ttaatatgtt gataaagtat taacagtaaa agaaaaatct atttttctct gaagataaga
    34981 agaaaaaagt ttttatgtct aactttgtta aaaaaataat tttaaataaa ataatttttt
    35041 tacaataaac attttttagt aataaaataa agatttaaga cataaaaaca caagaatata
    35101 tcttaaaaaa ataagataaa ttgtaaaatg atataatttt gagaaaaact caaatgcata
    35161 tacacaaatt aaataacagg aggtgcaagt atgcgtcttg aattagggaa aatctttata
    35221 aaagatattc aatttggtga tgtaacagaa gtaaaagatg gagttttatt catcaataag
    35281 caagagatgc tacaagaaat tggtggagat gagcatatta aatctataga tatagaatta
    35341 gctcgtccag gtgaaagcgt aagaataaca cctgtaaaag atgttattga gccaagagta
    35401 aaagttgaag gtaatggggg aatcttccct ggtatcatgt ctaaggttga cactgtggga
    35461 gaaggaaaaa ctcatgcttt aaaaggtgta gctgttgtaa ctactggaaa aatagtaggt
    35521 ttccaagaag gtataataga catgactgga gaaggagcta agtacactcc attttctaaa
    35581 ttaaataatg tagtagtaat agctgaacct attgacggtt taaaacaata cgctcatgaa
    35641 aaagctgtta gaatgatagg attcaaagca gcaatgtact taggagaagt agcaagaaat
    35701 cttactccag acgaagtttc agtatatgaa actaaacctc ttcttgaatc aataaaagaa
    35761 tatccagagc ttccaaaagt aggatatgtt tacatgcttc aaactcaagg tttattacat
    35821 gatacttatg tatatggagt agatgcaaaa caaatagtac caactttatt atatccaaca
    35881 gaattaatgg acggagcaat tgtaagtggt aactgtgttt ctgcatgtga caaaaaccca
    35941 agttatgttc atataaacaa tggggttgtt gaagatttat atgcaagaca tggtaaagat
    36001 ataaactttg taggtgtaat tataactaat gaaaatgttt acctagcaga taaagaaaga
    36061 tcttcaaact ggacttctaa attatgtaaa tatttaggat tagatgcagt tatagtttca
    36121 caagaaggtt ttggaaatcc tgatactgac cttataatga actgtaagaa gatagaaatg
    36181 caaggtgtta aaacagttat agttacagat gaatatgctg gacgtgatgg aggttctcaa
    36241 tcacttgcag atgcagatgt aagagctgat gctgttgtaa caggtggaaa tgccaaccaa
    36301 gttgtagttc ttcctaagtt agataaagtt attggtcatt tagaagtagt agatgtaata
    36361 gctggtggtt ctgatggaag tttaagagct gatggaacta ttgaagttga aatccaagct
    36421 ataacaggtg caactaatga aacaggattt ggtcatttaa ctgctaaagg atattaagaa
    36481 gtatttcatt aaacgattga gtaatgttaa taaaacatat tatagataaa ttataataag
    36541 tgttatagat atataaaaat atattagaaa tataataagg aggattatta tgagtttact
    36601 tagtaataaa aaggttctta taataggtga ccgtgatggt ataccaggac ctgcgataga
    36661 agaatgtgta aaaacagtag aaggagcaga ggttgttttc tcatctacag aatgctttgt
    36721 ctgaacagct gctggggcta tggacttaga aaatcaaaac agagttaaag atgctgctga
    36781 taaattcgga gctgaaaatg ttgtgatttt actaggtgct gctgaagccg aagctgcagg
    36841 tcttgcagcc gaaacagtaa ctgctggaga tccaactttc gctggaccac ttgctggagt
    36901 tgccttagga ttaagtgttt accacgttgt tgaggagcca attaaatcat tatttgatga
    36961 aagtgtatat gaagaccaaa taagtatgat ggaaatggtt ttagaagttg aagaaataga
    37021 agaagaaatg tctggtataa gagaagaatt ttgtaaattt taatgcctaa aagcaaaagg
    37081 ggtgaaacta agagatggga aaactaaaag cagtacatta tattaatcag ttctttgctg
    37141 gtataggtgg agaagaaaaa gctgatacta agccacatgt ggcagaaact ttacctccaa
    37201 taagtttaca acttgataaa ttattaggtg aagatattga aatagttgga acagtagttt
    37261 gtggagatag ctatttcaat gaaaatattg atagtgcaag tgaagaagtt ttatcaatgg
    37321 taaaaggttt tgaaccacaa cttttcatag ctggtcctgc atttaatgct ggtagatatg
    37381 gagttgctgc tggaacaata actaaagttg taaaagatgc tttaaatata ccagctttaa
    37441 caggtatgta tgttgaaaat ccaggagcag atatgttcaa aaaggatgtt tatgtagtag
    37501 aaacttctga ttctgcagca ggtatgagaa aagcacttcc taagatagct aaacttgcag
    37561 taaaacttgc taatggagaa gaaattggaa ctcctaaaga tgaaggatac atagctagag
    37621 gaataagagt taactacttc catgaagaca gaggttctaa gagagctgtt gacatgttag
    37681 ttaagaaaat aaaaggtgaa ccatttgaaa ctgaataccc aatgccaaac tttgatagag
    37741 ttgacccaag caaagctgta aaagatttat caaaatgcaa aatagcttta gttacttctg
    37801 gtggtatagt tccaaaaggg aatccagata gaatagagtc ttcttcagct tctaaatatg
    37861 gaacttattc tatagcagga gttatggatt taacagaaga gacttatgaa actgcacatg
    37921 gtggatatga cccagtgtat gcaaatttag atgcagatag agtattacct gttgatgttc
    37981 ttagagactt agaaaaagaa ggtgtaattg gaaaattaca tgagactttc tatacaactg
    38041 taggtaatgg tacatctgtt gcaaactcta aaaaatatgc ttctgaaatt ggagcagcat
    38101 tagtggctga tggtgtagat gcagtaatat taacttctac atgaggtact tgtactcgtt
    38161 gcggtgcaac gatggtaaaa gaaatagaaa aaactggact tccagtagtt catatgtgta
    38221 cagtagtacc tatttcatta acagtagggg ctaatagaat agttccaact atagcaatac
    38281 ctcatccact tggaaatcca gcgcttgacc ctacagaaga aaaagcccta agaagaggac
    38341 ttgtagaaaa agcattaaat gctttaacta cagaagtaga tggtcaaaca gtatttgaaa
    38401 aataaaaata acacacacat atattatata gataaaaata taaacacaca ctaaaaataa
    38461 aaaataacta tacacaaaaa aataatatag atttcatgaa tggataaatt ggagttattc
    38521 attcatgaaa tcttaaaaaa tgccaaaata cataaacaat aatagaatta aatatacaat
    38581 aaaatacaat aactagaatt tttaataaga ttaaaaaata agtgttcata aaatttatgg
    38641 aggtgcacaa aatgacttat ccagttttaa aaggggcagg ctatgtactt attcatactc
    38701 cagatatgat agtgcaaaat ggaagtactt gtacagttga aagagcaaca aatccagact
    38761 cagaattttt aaaagaagta agtaatcata taagaagtta tgaagatgta gttaactaca
    38821 tgccaaatca agtttatata ggaaatagaa gaccagaaga attaagagat ttaccaatgc
    38881 catggtgtga acaaaagatt gagggaacta gaaatggtaa gtttggagaa ataatgcctc
    38941 aagatgagtt catagcttta atgcaaataa gtgatgcatt tgatttagta aaattatcac
    39001 aagaatttat tgatgaagta aaaccaaaaa ttgaaaacaa ctaccctgaa attgcaccat
    39061 ttgtaggtaa attaaagggt gatgatatag aagaaggtaa agaattagta gcaacacaca
    39121 tagctgaagg attataccat gatggaaaat tcgttggtta tgtaaaaaga gcacatgatg
    39181 tagatgttaa cttaaatgcc catacaatgt ttgaaaatct agtagtaaaa gcatctggag
    39241 ttttatctgc tattcaaatg ctaagacata gtaaaataga ccctgctgaa atagattatg
    39301 ttattgagtg ttcagaagaa gcttgtggag atataaacca aagaggtgga ggaaactttg
    39361 ctaaatcaat agctgagata gtaggacttc aaaacgcaac tggttctgac acaagaggat
    39421 tttgtgcagc accaactcat gcattaattc aagcagcagc tttagtaaaa gctggtatac
    39481 ataaaaatgt aatggtagta gcaggtggag caagtgctaa gcttggaatg aatgctaaag
    39541 accatgttaa aaaaggtctt cctgtacttg aagatgttgt tggaggattt gcagtacttg
    39601 tatctgaaaa tgatggtgta aatccagtta taagaactga tttaacaggt aagcatactg
    39661 ttggaactgg ttcttcacca caagcagtta tgacagcact tataacttca ggtcttgata
    39721 gagctaattt aaaaataaca gatgttgatg tatattcagt tgaaatgcaa aatccagata
    39781 taactaagcc agcaggagca ggagatgttc cagaagcaaa ctacaaaatg ataggagcac
    39841 ttgctgttaa acgtggagac ttagaaaaga aagaattgaa agattttgtt tctaacaaag
    39901 gattaccagg atgggcacca actcaaggac atataccatc aggagctcct tatataggat
    39961 ttttaataga tgatttaact acaggaaata gaaatagagc tatgatagtt ggaaaaggta
    40021 gtttattctt aggaagaatg actaacttat ttgatggagt atcttttata gctgaaagaa
    40081 atacaggtgt tactgaagag acttcaggaa tatctaagga tgaaattaag aagataatag
    40141 ctgaatctat gaaaaaacta gcattagata tgttagaaga ataggggtga ggatatgtca
    40201 aaaaaagtaa tcgcagatgt attcttagaa gtagctaatg caatagaaag cggcgaattt
    40261 ggcaaaaaag taaaaattgg tgttactaca cttggaagtg aacatggtgt agagaacatg
    40321 gtcaatggtg cacaattagc aaaatctaat ttatttgata ttgtgcttat tggaccaaaa
    40381 gtggaaactg accttgaagt agttgaagtt aatgatgaaa aagaaatgca tgcaaaaatg
    40441 gaagaattat tagattcagg atatattgat gcttgtgtta ctatgcatta taattttcca
    40501 ataggtgtat ctacagtagg tagagtaata actccagcaa aaggaaaaga aatgatactt
    40561 gcaacaacaa caggaacaag tgctactaat agaatagagg caatggtgag aaatgccatt
    40621 tatggtattg ctacagcgaa atcaatgggt aacaaatgcc caaaagttgg aatacttaat
    40681 gttgatggag caagacaagt tgagaagtgc ttaaaagaat taaaagataa tgggtatgat
    40741 atggaatttg cggattcaat tagagcagat ggtggatgtg taatgagagg taatgattta
    40801 cttgtaggtg cacctgatgt tatggttact gatacattat ctggaaatat atttatgaaa
    40861 gtattttctt catatactac aggtggagat tatgaagctc aaggatttgg atatggacct
    40921 ggagttggag aggactatga tagaaaggta cttatagtat caagagcatc aggttctccg
    40981 gtagtagcaa atgctttaaa atacgcttat gatgtcgtaa agggagatat aagtaatgtt
    41041 gcaagaaatg aatttgcaaa ggttaaaaaa gcaaaatttg ctgacattat atcctctctt
    41101 actaaaaaag aagttaaagc tgaaaaagta gaagttaaaa tgccagataa agagattgtt
    41161 actcgtcaaa tagctggtgt tgatataatg gatttagaag atgcagtgtc tgagttatgg
    41221 aaaaacggaa tctatgctga aagtggtatg ggttgtacag gtccaatagt tttagtaaat
    41281 gaagctaaag gagacttagc agttgaaact ttagttaaag ctggatatac tgcaaaataa
    41341 gtacactttt tatgtaaata agaacatata cttataatca ataaaattat aagtatatgt
    41401 tctttttatt ttctactttg tcaatgttta tatattaaca taatcttttt atttgatttt
    41461 ctagctaatt tatcatattt gttcaattga atttaagttt ttagctaaat aaaactaata
    41521 aaatattaaa gtaaaattaa taaaatctga aaaaatttta gaaataaact atctattaga
    41581 taaaaagaag gctaattagt gatataatat aattaggata aaatttatta tttggaggca
    41641 aaatcatgag caaagtaaaa aaagtagtag aattgttgga atctaaaggt attgatgcac
    41701 tatatctaac aaagaaaact aatgtaaact atataagtgg ttttcctgat gaagaagcat
    41761 atgcagtgat ttgtaaatat ggaaactttt tagttactga tagtagatat atggagcttg
    41821 cggaaaatgt ttgcgaaggt tttgaaatta taaattggca taattttgat agaagtgttg
    41881 caaaggcagt taaaagtgta tgtgataaag tgggaataaa gaaacttgga tttgaaagaa
    41941 ctaatatagt gttcgataaa tatgaagaac ttaaaaatct gattgagaag gataatggag
    42001 aattaatacc tacggaaaat attgtagaga ctttgagata tataaaagac gaagaagaaa
    42061 tcaaaaatac aagaaaagct tgtgaaatag cagataaagc attagaagaa ttgattccac
    42121 atataaaagc tggagttagc gaaattgaac tggctacgaa gttagagtac tttatgaaga
    42181 tgaatggagc acaaaatata ggatttgaaa ctatattgat atcaggagca aagacttcat
    42241 tgcttcatgg taagcctagt gataagatta tagaaaaagg tgattttgta cttatagact
    42301 atggtgctat gtataatggt tatatatctg acacaactag aacttttata gttggggaag
    42361 cttctgaaaa gcaattagaa atatataatt tagttaagga agcccaaaat gtaggggttg
    42421 aaaacatgaa agttggtgta catgcgacaa ttccagatgc tgagataaga aaagttgtca
    42481 aaaaatacga agactattac tatcagggta taggacatgg agtcggtaga gatgttcatg
    42541 aagaaccttt cattggtaat tatggtgata aaatcataga agatggatgt ataataacaa
    42601 tggaaccagg tatttatttc cctggatggg gtggagttag aatagaagac actgttttga
    42661 ttactaaaaa tggaccagaa agacttacta aattccctaa agatttgatg attttagaca
    42721 aataatttaa tttatatata tttttacata aaatataaca taatctcact attaagccct
    42781 atttacatat tatgataaag agggcttaat tttattgtga gaggtgataa tgtccatgta
    42841 taaaaaacat aaatttataa aaaatataaa acaagcctgg tataaaatca aactaattga
    42901 tagatgcctt ataattgtaa tggcaatatt aatgtttcaa tctatataca atttatttgt
    42961 taatgaagta aattcacaag acactacaac tattgatgta gtagtaagaa ctacttcagc
    43021 agctatattt ggatactttt taagtgttaa ttttataaag agaccttcaa gaaagtatat
    43081 aaatactgat gtatcttcaa atttttttat agataataat ttatctaaga aaagtcaaga
    43141 atcaagtcag aataatgtaa tgaatgtcaa aaataccatt ggatttactt cagaaactga
    43201 taattatgaa aagaaaatac ctactaataa tactgaagat tttgaagatg gagagactag
    43261 tgaattacaa attgttatag ctactgtaat ttgtgtagta gcattaacag tactttttgt
    43321 tgtaagaaat tttacaacta caacatcagc ttctttaggt actatttcac agatgagaga
    43381 ttttgtctca ggatgcgtgg gttttttact aggttgtcca agtagacctg attaaaaatg
    43441 tgattactaa taaaaaagat tgttaaaagt atcagtataa taatacttag acattaaggc
    43501 atataattat aatcttataa gatttgatat cctattttta tactgatact ctaaaatatt
    43561 tattaaaaca tttttaatat tacatttaaa taaaatatta tggctacata aaagttaatt
    43621 tatatgaata gatgccatat attcaataaa aagtttcata ctatgagata tgtattgatt
    43681 tcttctccaa agaaccccaa tatttgcagt aattgcacgc tctaatggta ttgaacagag
    43741 attttttgta ttttgaaata tttctttata tagtattgtt gaagccaagt cattttctag
    43801 taaataacgt atggtagaaa gttggtttga gtgtaaaatt atatttggct tagctttttc
    43861 aagtcttttt gtaataatct tatagtgata agaaccttca gataagatta caaaaggtac
    43921 attttttaac atataacttg atataatggg gtgttttgcc aattcatttt tgggatttgt
    43981 aactaaatat aattctgtct tatagattgt ctttgaatct atatcatcat aaatatcact
    44041 atcaattata ccaatacaaa aatcaagtgt agattcttca atcattttag ctccaacaaa
    44101 tgttggaact tcaaaaattt taagctctat atctggataa attacattaa atctaggaag
    44161 tattttcgaa agtaaaaatg tacctaaaac tgtaggaata cctattttga gagaagcttt
    44221 tctctttttt cccaaatcca gtgcgtcaca ttgaaaatcc tcaaattgtt ttataaaatg
    44281 ttttgacttg tctaaaaaga tttttccttc aggcgttaac tctattttat tacctattct
    44341 ataaaaaagt tcaaagccaa gttctttttc taattcttta attgctaatg ttatggatgg
    44401 ttgagaaatg tgaatacttt ccgcagcctt agtcatgttt ttatatttac agacagtttg
    44461 aaaatagtat aaatagttta tattcatttg gtattacttc ctttcattta cgtattagtg
    44521 acaagtatat aattaacaat agtataagtt ttgtatattg ttgtaaaaaa atagaatagt
    44581 tttaaactat catatcataa gtttttgata ttttcaatct attgagaata gtgttattat
    44641 taaattaaca aaagagaata gctgatatgg tttactctaa atcaatctat aatacagtta
    44701 tatcaacgaa tattaaaaaa atatctatta aaaaataaaa aatattttta caattaaatt
    44761 gttaattaaa tcgtaaagaa aaaaatgata ttat
//
LOCUS       DBGJFK010000028        42609 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.028, whole genome shotgun sequence.
ACCESSION   DBGJFK010000028 DBGJFK010000000
VERSION     DBGJFK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.028"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            179..946
                     /locus_tag="ACOIAP_001788"
     CDS             179..946
                     /locus_tag="ACOIAP_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HGZ2638674.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            1231..1428
                     /locus_tag="ACOIAP_001789"
     CDS             1231..1428
                     /locus_tag="ACOIAP_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2638675.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            1457..2533
                     /gene="vorB"
                     /locus_tag="ACOIAP_001790"
     CDS             1457..2533
                     /gene="vorB"
                     /locus_tag="ACOIAP_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HGZ2638676.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            2536..3255
                     /locus_tag="ACOIAP_001791"
     CDS             2536..3255
                     /locus_tag="ACOIAP_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HGZ2638677.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTVEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            3268..3807
                     /locus_tag="ACOIAP_001792"
     CDS             3268..3807
                     /locus_tag="ACOIAP_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HGZ2638678.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIRVPVTEIAQNLGNEKAANICMLGAMVKNLDLFTKEEFENGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            3964..5022
                     /gene="buk"
                     /locus_tag="ACOIAP_001793"
     CDS             3964..5022
                     /gene="buk"
                     /locus_tag="ACOIAP_001793"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047761 - butyrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HGZ2638679.1"
                     /translation="MKILVINPGGTSTKISVFKDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFEDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKQGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVIEKVSYIAPVEVVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            5040..5933
                     /locus_tag="ACOIAP_001794"
     CDS             5040..5933
                     /locus_tag="ACOIAP_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HGZ2638680.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIENISKEIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMVNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPNCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            5963..7171
                     /locus_tag="ACOIAP_001795"
     CDS             5963..7171
                     /locus_tag="ACOIAP_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGZ2638681.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEVTQKVLKERGKFALAYGPTKGEDELLELLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVSKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIREEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            7195..8454
                     /locus_tag="ACOIAP_001796"
     CDS             7195..8454
                     /locus_tag="ACOIAP_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2638682.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEKEEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            9099..10562
                     /locus_tag="ACOIAP_001797"
     CDS             9099..10562
                     /locus_tag="ACOIAP_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGZ2638683.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAVSWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTTLPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKYEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKENKHELN"
     gene            10618..11754
                     /locus_tag="ACOIAP_001798"
     CDS             10618..11754
                     /locus_tag="ACOIAP_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2638684.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKIAEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLIDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVEIFTKVMEEFGIYEDEQVLLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINPYAKDRVIDGIKILALTGFNLFENSELLKKMKEE"
     gene            11779..13197
                     /locus_tag="ACOIAP_001799"
     CDS             11779..13197
                     /locus_tag="ACOIAP_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGZ2638685.1"
                     /translation="MTNKTEGKKKKLTFPDAYVLMIGLIVFAAIMTYIVPSGTYSRIE
                     DLNTGNMLVQAGSFKYGEQHPVSIMDVFRAIPSGLGKNSVTIFFVLIIGGAFGIVNFT
                     GSLDVLIGRVISKSQGSKKGEIIITSLVLTFGLAGGVVGMYEECIAFLPILMTLCIAL
                     GYDALVAAGILLLGLASGYGSATINPFTVGLAQGISGLPLFSGMWFRWIFWICTMILL
                     SGYIIFYCKKIKKDPSKSLVSDIDYSHWQLDESSIKEKLSSGNIRVLVTFFGGILVLM
                     IIIVKFSLGMSDLSAYFFALGILCGVVYGMSPNKIASAFVKGMQEMVYPAILIGFASS
                     IVVILEQGVILDSIVHGLSLVLNYVPRIFSGGVMMIMQSIINLFIPSGTGQAMVTMPL
                     MAPLADVIGVPRQVAVLAYQMGDGFANGIVPTLGVLMAGISIAHIPYTRWFKFASKII
                     LMELVLGFIFLMISVQINLGPF"
     gene            13409..14527
                     /locus_tag="ACOIAP_001800"
     CDS             13409..14527
                     /locus_tag="ACOIAP_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C45 family autoproteolytic
                     acyltransferase/hydrolase"
                     /protein_id="HGZ2638686.1"
                     /translation="METLKIRNIELSGTNYEIGYELGKLIANTPKILEGQINKSNVVT
                     KEEEKEMLELFDKYCPGLNEELKGFADAVQVNCNQILYYTMTYLKPGCSQVALAPELT
                     TNGHVLFARNFDFSHNMEDFVLCKTKVKGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSVGLRKPAVVGLQFWAVIRYLLENCKDVDEALEYIEDMPIAYNINLLLADK
                     SGNIALVETLDGKKGVNRINRLEKQREHFLHSTNHIHIDELHKLEPQSIKNSIHRYKL
                     IKEYINNSKKVGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNTGKFNILWGG
                     LESNNWESYYLKDDVKATTHLININIEKAPSDFFDFVE"
     gene            14678..15547
                     /locus_tag="ACOIAP_001801"
     CDS             14678..15547
                     /locus_tag="ACOIAP_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HGZ2638687.1"
                     /translation="MDYLEYFEKAVIYIENNLQENITVNDVAKESGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVNSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGNKKKLELDFMRHLIGNITIKPVIKEIDEIKIIGIKDKVILENNSLPE
                     LWDKFRKVHQIVPNTLPSERVFGICEATSEIHLISESMEFNEIIGVEVSSYESIPNSF
                     VSKTITEGKYAVFTHTGSLENLDKTYEYIWGTWFLNSKEEFDTRDDFEVYDERFLGPN
                     NINSQIDIYIPIK"
     gene            15922..16467
                     /locus_tag="ACOIAP_001802"
     CDS             15922..16467
                     /locus_tag="ACOIAP_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HGZ2638688.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNKVADKA"
     gene            16480..17493
                     /locus_tag="ACOIAP_001803"
     CDS             16480..17493
                     /locus_tag="ACOIAP_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HGZ2638689.1"
                     /translation="MDENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEVVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVSPNCISVVNGEDMQKKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     AKVISPLAGNIGGLLIISIICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPISVIIAYGVAVF
                     ALR"
     gene            17715..19688
                     /locus_tag="ACOIAP_001804"
     CDS             17715..19688
                     /locus_tag="ACOIAP_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2638690.1"
                     /translation="MSVTEKIPSIDHKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAIIKYIKGQGYKLEIKDEQILNKIIDINRKNVFSLNSKEDRVEF
                     ILNYLTELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFNNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKETKKVKDYDVKFDLLKSYDEYFIAREIKHIISEMFECILNDEE
                     IIYLTIPLVSGNAPASECALNSSRINKNIDELMESIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILDSLEKMMDNLMDLGCIDDKFRKNIFNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIKYANRNIKIILMTMFPCENKMDSDLLVKIYE
                     EILKIGQDVKLTNKISKCRSFLEFKKVLLKNLM"
     gene            19758..20117
                     /locus_tag="ACOIAP_001805"
     CDS             19758..20117
                     /locus_tag="ACOIAP_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HGZ2638691.1"
                     /translation="MKVLVILFAAYILNTILIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSNGFIKFGEILKGRTVMAKFKEIEDIEGLDIYSAEQKFKNEES
                     IVQAIKFIKEKINVSFN"
     gene            20152..20508
                     /locus_tag="ACOIAP_001806"
     CDS             20152..20508
                     /locus_tag="ACOIAP_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGZ2638692.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     ISTLRSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKNEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            20545..21837
                     /locus_tag="ACOIAP_001807"
     CDS             20545..21837
                     /locus_tag="ACOIAP_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGZ2638693.1"
                     /translation="MLDLNRKLAKLEEEGKKIRVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNENDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAEIKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLEHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEYMDGYGAYTCYGTIEKYDVAKAMKAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            22273..22911
                     /locus_tag="ACOIAP_001808"
     CDS             22273..22911
                     /locus_tag="ACOIAP_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638694.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            22918..23760
                     /locus_tag="ACOIAP_001809"
     CDS             22918..23760
                     /locus_tag="ACOIAP_001809"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HGZ2638695.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGILQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            23821..26448
                     /gene="ppdK"
                     /locus_tag="ACOIAP_001810"
     CDS             23821..26448
                     /gene="ppdK"
                     /locus_tag="ACOIAP_001810"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HGZ2638696.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRKEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDNALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGVEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            26662..26907
                     /locus_tag="ACOIAP_001811"
     CDS             26662..26907
                     /locus_tag="ACOIAP_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HGZ2638697.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKR"
     gene            complement(27197..28507)
                     /locus_tag="ACOIAP_001812"
     CDS             complement(27197..28507)
                     /locus_tag="ACOIAP_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HGZ2638698.1"
                     /translation="MNKKVSKIVAIGCGVGIITANLIPVYADNSTSSINKVDNSIVSD
                     STKRTSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFP
                     YDQIGLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMK
                     LKKDLGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEY
                     RFESFRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVA
                     PTKPEQGNLTDDEYKVLMDKYGKDYDRYKKEVEEYNLERQTYAAGLTTYANYLQQKYN
                     TENGLVTLEDNKKALKKGLIDSYAQLLALEDTIQITKKQLELSEKQLKNTKLRYDLGL
                     ITLTDYKKQVVSNEDAKNNYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(28529..31663)
                     /locus_tag="ACOIAP_001813"
     CDS             complement(28529..31663)
                     /locus_tag="ACOIAP_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HGZ2638699.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQIGQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     NNLLISSVIAFIVIFAFLKSVRASLVVAIAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSIDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTDGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDTPLFDK
                     VSELYKRLLSVCLRHQRLVVISSLLIFIASLFGMSFIGMDFMPAADKGELAISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNNTANIAIELESQKNRKRSTDE
                     VEKEIIDRVATVPDCKINVSQNSSVMGGTSGADFTLEMKGPDLDVLKILGKEAEKQFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGINTAEIAGLLRTAINGDSVTTATIDD
                     YKVDVNLKFKADSIDNLEDIKQLKVNSTTGKEVPLGAFSDIKMADGLQSISRTDGNFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGQTEMMNESMASLGFSMLIAI
                     VLVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTISTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGDI
                     KRKIIKKPKLKAKV"
     gene            complement(31667..32890)
                     /locus_tag="ACOIAP_001814"
     CDS             complement(31667..32890)
                     /locus_tag="ACOIAP_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGZ2638700.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEEPEPEKPIAVSVQKAVGGEIE
                     NTNAFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPDLENSVKQSK
                     AALDLAKASYSSTTGGSLEAQVNQAKTALDNAKIQYDESQRNYDNNKILYEQEVISLD
                     QFKKIEFALEQSKQQLDSAQRSYDTVTSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTAPVDGTITAKNFDAKEMITQSQPAFIISNPNILEVNLNVAESDIDKFKKDGNVE
                     VIIEDQRILGKIDYVPSVVDPQTSLYPIKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEEKGKKYVYIANKDNIAKKKLVQTGIVTEDKIEIKSGVSEKDTVVIGGIS
                     LISDGTKIFPVEKEK"
     gene            33142..33627
                     /locus_tag="ACOIAP_001815"
     CDS             33142..33627
                     /locus_tag="ACOIAP_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGZ2638701.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFRESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFELFGAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            complement(33738..35966)
                     /locus_tag="ACOIAP_001816"
     CDS             complement(33738..35966)
                     /locus_tag="ACOIAP_001816"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HGZ2638702.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFIPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAETGEYKGKYIKGKESKFDTLEDANKIIASIASKTGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKNLSKDEQLVYDA
                     IKDRFIANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKINQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEEYTFDSKTKKFTKTKEKKQKKDTTNA
                     EKEVAISKDSNNKKESKNGDENQPLGKCPVCQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDALLKYNKNPDTGYFNWKIEF
                     DN"
     gene            36079..36510
                     /gene="dut"
                     /locus_tag="ACOIAP_001817"
     CDS             36079..36510
                     /gene="dut"
                     /locus_tag="ACOIAP_001817"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGZ2638703.1"
                     /translation="MYTLKVKKINDDAIIPNFAHKGDAGMDLYSIEEVVIPSGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIIKPIYDINIEEVEELSDSERGKGGFGSTGF"
     gene            36770..37960
                     /locus_tag="ACOIAP_001818"
     CDS             36770..37960
                     /locus_tag="ACOIAP_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HGZ2638704.1"
                     /translation="MNFNQKRIAASVMATAIIIPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKDGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTSENTGNSSNDIVKGTKVVTAKSLNLRTGPGTSHSKIATL
                     SYGTEVGRISENGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGAESVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLIFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(38198..38770)
                     /locus_tag="ACOIAP_001819"
     CDS             complement(38198..38770)
                     /locus_tag="ACOIAP_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HGZ2638705.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(38799..39065)
                     /locus_tag="ACOIAP_001820"
     CDS             complement(38799..39065)
                     /locus_tag="ACOIAP_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HGZ2638706.1"
                     /translation="MKDSSRAELMRKIQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            complement(39065..39274)
                     /locus_tag="ACOIAP_001821"
     CDS             complement(39065..39274)
                     /locus_tag="ACOIAP_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HGZ2638707.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            39543..40403
                     /locus_tag="ACOIAP_001822"
     CDS             39543..40403
                     /locus_tag="ACOIAP_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HGZ2638708.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            40451..41479
                     /locus_tag="ACOIAP_001823"
     CDS             40451..41479
                     /locus_tag="ACOIAP_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HGZ2638709.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRNLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNIDIQNLLIIRDIIRAPFNDINSNLDNCFDKF
                     KESLYKKEENYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEVMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDILEDLMLYRMHEDEYKHEIENIIKMLDEDLDNEKIYINKCN
                     DLNVVNKI"
     gene            41843..42349
                     /locus_tag="ACOIAP_001824"
     CDS             41843..42349
                     /locus_tag="ACOIAP_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HGZ2638710.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT        15839 a         5038 c         7488 g        14244 t
ORIGIN      
        1 ttaaaagtaa gaataataag gacatagtga gtattttgtt tttattttac aaattaagta
       61 taatattttt gttttataaa atataattaa gataaataga taattttgca attttaatat
      121 ataatgttta gtagagtgtg ggagtagcac ttaatatttg cagaaggagt ttttgtatat
      181 gggagaaata ataaatgcat tagatagagc cctagacata attttgctgt tatatcatga
      241 aaagagagaa atgggaatca ctgaaataag caaggctatg ggagtatata aaagtactgt
      301 acatagaact ttggtcactc ttgaaaataa aggttttgtt atacaaaatg cagaaaatgg
      361 taagtattgg ctaggaataa atttatatgc aataggtatg gttgtgggag aaaaaatgtc
      421 attgactgaa atcgtaaaac catatacgaa aaaattaaat caagaattta acgaagtagt
      481 taatgtatct atattagaag aaagagctca agattctcca agaagtatta taatacataa
      541 agagtatggt tcaaatcaat tactttcagt aaatccatcc gttggctcaa gtagtgaatg
      601 ttattgttcg gcagtgggta aatgtcttat ggcatttaat gattctatag attttgaaaa
      661 atatagaaaa acaccaatac acaagtatac agaacataca attgataatt gggatgatat
      721 gatgcttttt ttagcaaaaa taaaagaaca aggatatgct atagatgatg aagaactaga
      781 acatggacta acttgtattg gagcacctat cttagataaa aacaataaag ctattgcagc
      841 aataagtttg tcaggtccaa ctataagaat gagagaaggg gactttgagt ataagattaa
      901 aagagttata gaaactgcaa aaagtatatc tgaacttttt agatgatttt ttaatctaga
      961 taagaaaaag aggttatatt taaattgtta tttgtaaata tcagtttaaa tatagcctct
     1021 ttttctttaa tctaaaatta aatattctta aaatttaaaa tgttattgaa atatataagc
     1081 gaatgtgtta tcttttaatt aagcaataaa aatagaacaa ggttctatac tatagaacaa
     1141 aaattaatgc atatatagta tttatataaa atataaatat tatatattta aaattaagta
     1201 aaaatattac ataaagggga gatttgagaa atggaaaaag tcaagttgag tgttgaaaga
     1261 tgtaagggat gctatctttg tattgaagct tgtaaaaaag atgcaataag tctttctgac
     1321 tacacaaata aaaaaggctt tgtaactatt aaagtcgatg aagaaaaatg tattcaatgt
     1381 ggcgcttgtt atacaatgtg ccctgactta gtatttgaga tattataaat tatttttatt
     1441 agaggggaga aaaggtatgc aaagtttatt aattaaagga aatgaagctt tagcagaagg
     1501 tgctatacgt ggtggctgta gattttatgc aggttatcca ataacaccac aatcagaaat
     1561 attagaaatg atggcatgga gacaaaaaga agttggagga gtatttatcc aaggtgaatc
     1621 agaaatagcc agtgtaaata tggttatggg agcaagtgca cttggagcaa gagctatgac
     1681 ttcttcatct ggtccagggt tttcattaaa acaagaaggt attgcatatt gggtatcagc
     1741 tggtttgcca gcagttgtag catgtgtaca aagatatggt ataggtgatg gatttatagg
     1801 agctggtcaa gataattatt ggcaagcagt aaaaggtggc ggaaatggag attatcattt
     1861 aatcgtgttg gcacctaata gtgttcaaga aaatatggat atggcatatg aatcttttga
     1921 actagctgaa aaatatatgc atccagtact tatactttct gatgctacaa taggtcaaat
     1981 ggtagaacct tgtatagcac caccaatgaa agaatacgat atggataaag ctccatgggc
     2041 tgcaaaagga acacctgtag gagaaaaaaa taaagtaata actgatataa catactttga
     2101 agaccaagat acatggcaaa aagggtatat agaaaaaatg agaaaagttc aagaagatga
     2161 acaaagatgg gaagaaatag aaatagaaga tgctgaagtg gtgtttgtgg catatggtat
     2221 ttcatcaaga atagcagaag gtgcagttag agatgctaga gcaaaaggaa tgaaattagg
     2281 actaataaga ccaaaaacat tgtggcctta cccaagaaag gcatttaaga aattaagtga
     2341 ttcattgaag ggacttgtaa cagttgaaat gaacatgatg gcacagatga aggaagatgt
     2401 aattatagca tgtgataata gatttccagt atattcagta gcaacagctc aatatatggc
     2461 agaagtaaat caattaatag attttgctca acagattata gatggaaaag ctaagcaaga
     2521 ggaggtattt taattatggc taaaaaagca ccagcaataa tgatgtgtga aaatatgttc
     2581 tgtggaggct gtggacactc tatagtcgat agaattattg gagaagtatt aacagaaatg
     2641 gatatatgtc aagatacaat tatatgttca gatataggtt gcaaccatat gttccaattt
     2701 agtatgaatg tagatgttgt cgttccacct catggtaaaa tgggagcagc aatggcagct
     2761 atgaaaagag tcagaccaga taaatatata tttacaatag ctggagatgg tggagcttat
     2821 gcaatagggc ttggagaaac tatgtcagct gctactagaa atgataatgt aatatttctt
     2881 gttatgaaca ataacatgtt tgcaatgaca gggggacaaa tggctccaac tactgtagaa
     2941 ggtcaatata cagcttctac tccagcgggt agaaattacg cagatcatgg ttcaacattt
     3001 gatgttgtaa aagttatggg aaatttagat atagcatatc tagcgagagg aacaataact
     3061 aaccctaaag aaataaatac aacaaaaaga tacatcaaaa aagctctaga aaaacaaaaa
     3121 gaaaagaaag gtttttgctt aatagaagtg cttgtaccat gtccaacaaa ctggggatta
     3181 aagccagtag atgctatgaa gagaattgaa aatgaacttg ttccaaagta tccacttgga
     3241 gaatttattg attagggagg aaataatatg ttgaatgaaa ttatatgtgc tggttttgga
     3301 ggacagggag ttcttacagc aggaaaaatt ataatgtatg ttgcatataa ggcagaaaag
     3361 aaaattacat ggttcccatc ttatggaaat gagatgaggg gaggaagtgc aaattgtaat
     3421 gttgttgtaa gtgatgaaaa aattgcaaat ccttgtgtaa aaaatccaga tatattattg
     3481 ggaatgaaca gcgtatcagt agataagtat gaaagtttaa tgaaaaaaaa tggttatatg
     3541 tttgtcaatg aatcactagt aagtaaggat agaaaataca gagaggatat taatgttata
     3601 agagtacctg ttactgagat agcacaaaat ttaggtaatg aaaaagctgc taatatttgt
     3661 atgttaggtg ctatggtaaa gaatttggat ttatttacaa aagaagaatt tgaaaatggt
     3721 atgtgtgaat actttgaaaa tcaaggcaaa ggtaaattta attctaaaaa tgtagaagca
     3781 tttgaagctg gatacgacta cgagtgaata ttttaaatat ttaaaataat tattgaaata
     3841 cttattttta tatgttagta tttaattaat aaaatataga acgtcgttct ggacaatagg
     3901 acaaaatctt tgtgcttgaa tataagaacg acgttctatg taatagaatt aggaggtgtt
     3961 aaattgaaaa ttttagtaat aaatcctggc ggtacatcca caaagatttc tgttttcaaa
     4021 gatgaaaatg aaattttgaa aaaaaatata acccatacaa gagaagattt aaaaaatttt
     4081 tctaaagtat ttgatgaata tgattataga aaacaactga tagtagatat tttaagtagt
     4141 gagaatcata gtataaattc ttttgatgca gtagttggtc gtggtggact tatgaaggct
     4201 ataaaaggtg gtacttatac tgtgagtgaa gaaatgattg aggatatgag aaatgaaata
     4261 aatggggaac atgcatcaaa tttaggtgca ttattagcta aaactatagc tgatgaaata
     4321 ggggtacaat catttgtagt agacccagtc tctgtagatg aatttgaaga tgtatcaagg
     4381 attacaggaa tatcagatat agaaaaagca agctggctac atgcattaaa tcacaaagct
     4441 gtttcaagaa aaattgcaca aaaactaggt ggaaaatacg aagattataa cttcattgtt
     4501 gctcatttag gttcaggaat atcgattgta gcacataaac aaggaaaaat gattgatgga
     4561 agtggtggaa ggtctgatgg tccattttct ccagaaagaa gtggtggatt gcttgcatat
     4621 cctcttatag aattgtgtta ctccggtaaa tatactcatg atgaaatggt agcaaaagta
     4681 agttcgattg gaggcatgta cgactatttg ggcacaaagg acatgataga aattgaaaac
     4741 agaatcaagc aaggtgatga aaaggcaaaa cttataatgg atgcattcat ttatcaagta
     4801 gcaaaagaaa tttctatgta tggagcttca ctttcaggca atgtagatag agttatttta
     4861 acaggaggaa tatctcattc agaaatggta gttaaaggag tcatagaaaa agtttcatat
     4921 atagctccag tagaggtagt accaggggag atggaaatgg aagcacttgc tcttggagct
     4981 cttagagtac ttaatggaga agaaatagca aaaacttatt aatatttagg agaaggagta
     5041 tgttaaaaga ttttaataat ttattggaag aagctaaaaa gcttgaacct gttatagtaa
     5101 gtgttgctgt tgcagaagac aaagaagtat taaaggctgt gaaatcagca acagatttaa
     5161 atattataaa gccaattctc gtaggagata aagataaaat agaaaatata tcaaaagaaa
     5221 ttggattaaa aggtcatgaa ataataggat gtcaaaatcc tgatgaatca gtcaaaaaag
     5281 ctgtagagat agtaaaaaat aaggaagcta aagttcttat gaagggatta gtaaatacga
     5341 gtgtgtatat gagagctata ttaaataaag aaactggtct cagaacagga agattattga
     5401 gtttacttgc agtatatgaa ttacctcaat accacaaact tctttattgt actgatagtg
     5461 gaataaatgt atcaccaaat ctaaatcaaa aaaaagatat aatggtaaat gcacttctta
     5521 ctatgaaaag tataggcatg gaaaatccta aaactgcgat acttactgca aatgaaatgg
     5581 tagaccctaa gatacaatct acagtagatg caaacctact tgttgagatg gaaaaatcgg
     5641 gagaaatacc aaattgtata gtggaaggtc caatagcatt tgatgtagca tttgatgcac
     5701 atgcagcaga acataaaggt atcaaaagta atattgctgg tgatgttgat ttactagtat
     5761 ttccaaatat agaagcaggg aatatattag gaaagtcatg gcttagattt aataaagcta
     5821 agtgggcagg tatagtttta ggagcaacaa atccaataat tttaggttca cgttctgata
     5881 cagctgaaat taaaataaat tcaatagcat tagcgtgctt agcatcacaa taagaaatca
     5941 ttattaagga ggataaatta ttatgaaata tgcaaaaaga atggatatgg taaaagcttc
     6001 agctataaga gattctcaaa agaaaatagc tcagaaggta gcaagtggtg gaacggttat
     6061 atcttttgct gcaggacttc ctgacccaaa tttatttcca atagaagaaa taagtgaagt
     6121 aactcaaaaa gtacttaagg aaagaggtaa gtttgcccta gcatatggac ctactaaagg
     6181 tgaagatgag ttgttagagc tattagtaaa aagaatgaaa gaagaggaaa atattgatac
     6241 aaaagcagaa aatattataa taactactgg gtcacaacaa gggatagcat taagtgctat
     6301 gattttatta gaaaagggag atgtagtagt tacagaaaat ccaagttact taggtgcaat
     6361 aaatgcattt agaccttatg aatgtgattt tttaggagta gatacagacg aagaaggaat
     6421 ggtaacagat gatttagata aattattatc tgaaaattct aacataaagg tgatatatgt
     6481 aataccaaca tttcaaaatc ctacaggaaa aacatggtct ttacaaagaa gaaaagattt
     6541 tatggaagtt gtaagtaaat atgatgtcat agtaatagag gataatcctt atggagaaat
     6601 aagatttaca ccagaacctc tacctacact taaatctctt gatactaaag ataaagtatt
     6661 gtaccttggg tcattttcaa aggtattatg tccaggattt agagttgctt ggatgtgtgg
     6721 taatgtagac atcatagata aggcagaact tttaaaacaa ggtatagatt tacagtcaaa
     6781 tcaattttct caagtacaag taatagaatt tttaaagaaa tacaacttaa atgaacatat
     6841 agaaaaaata agagaagagt ataaaaaaag atgcttacta atgttggatg ctatgaagaa
     6901 acacttccca gaggaagcta aatatacaga gccagatgga ggaatgttta tatgggttga
     6961 acttcctgaa agcataaatg tagatgattt attagataaa gccattgatg ctggagttgc
     7021 ttatgtttct ggagagtctt tctttgcaaa taatggtcca aaaaatacta tgagacttaa
     7081 ctatacaaca atgtcagaag aacaaattgt taaaggtgtt gagatacttg cagaagttat
     7141 aaaaaaagaa ctcaattatg cttgtgaata aatataaaaa gtgagggttt aaatatggga
     7201 gaaaaagaaa acggtataaa gtttggaaag ttaatgtttc aactcgttat tatagcaata
     7261 tcttgggaat tagtttatat tataccattt atccaatata cattatatga tccaatccta
     7321 aaagcattag aatgcacaaa tactcaacta ggttttttac ttacaattta tgggttaggt
     7381 aatatatttg gagctcctat aggaggctgg ttagcagata gatttgatta tagaaagata
     7441 attttaggtt ctgtatttct taatggagta gtatcatttt tgtttgcatt taatatgaac
     7501 tatccatttg cagttgctac ttgggtgggt tgtgcaatca catcattagt tatgaactat
     7561 ccttctatgg taaagatact tagagttata ggaaaagata atcaaggtaa ggtttatgga
     7621 tttaatgaag ctatggttgg agtttctggc gtagtaatgg gagcaatatt cttatatatt
     7681 tatacatgct ttgcaactcc tacattgggt atgagatggg taatgatatc tttaggaata
     7741 ttatcaatag caatgtgtcc agtattatgg tttgtaatta aagatgtaga tattaaagaa
     7801 gaaaaagaag aagcaggtga aaaaatgtct gctggtgatt ttataacagt actaaaatca
     7861 ccaaatactt ggctagtagg aataagtata ttctgtgtat attcattcac agttacaatg
     7921 tcttatttta caccatatat aacatctgta cttggaggtt ctgtagcact atctggtgca
     7981 ttagcaataa taagacaaca tggtctaaaa ttgtttggag caccatttgg aggatattgt
     8041 gcagacaaat taaaatctcc tacaaaagta cttttaccaa tatatgtatt tggtatagca
     8101 gtaatagttt tattcctagt attacctgca tcaactccaa tgactatatt catagctcta
     8161 acatttgtag taggtatatt aggttacatg ggaaaaggta tatattatgc agtacaagat
     8221 gaagtaaaag ttccagttaa atattcagca actactatag gtatagctgc agctttagga
     8281 ttttcaccag atgtattcca atttgcgtta ataggacact ggatagatac ttatggcaat
     8341 aaaggttaca catatacatt tatattccag atagcaattt tagttattgg aatactatct
     8401 tgtttatata tattaaaggt taaaaagaga agagcaagta aattagaagc ttaaatattc
     8461 aatttggtga ttaagtacat gtaaatacaa tacttatttt gatgaatgtg attgtataaa
     8521 taacataaaa aatatcaata gattaagttt tataataatg tttagagaat aaaatataaa
     8581 aatcaaaatg ttatcaagtt ttctaagttt tagcataaag ttacccctaa aggtataaaa
     8641 ttgagtagta attattatct attttcttac ttacataaac ctatttaatt taaattctaa
     8701 gagaatttca aaatagatgg cagttgtact caattttata cctcataata aatacgaaaa
     8761 tttaaaatct aactagatac tatttaatta tatattaata aatatatatt gtattattta
     8821 tataatagta atttcaggct tttcattata tgtattccaa tttatattgt ttgattattg
     8881 ttcaagcaca catcgttaaa aattttataa atttatgttt agatatgatt aatactcttg
     8941 attttagaaa taaatatttg tagattgtag attaaaaata atataaataa atagaaggta
     9001 gattttttag atatattaag atgaagatta tataaaatat tgaaatatag ctgtttaaat
     9061 tattgtctat aaatataaaa tgaatggtgg tgagttacgt gaccgattta gttaacacca
     9121 ttaatggaat tgtttggtca cctgtattag ttgcaatgtg tttgtgtata ggattatatt
     9181 tttcgttgaa attaaaattt tttcaaataa gagatgtaaa agaaatgttt actctcttgc
     9241 ttgaaggaga tagttctcat gttgggatat catcatttca aggctttgct acatctatgg
     9301 ctggaagaat agggactggg aatatagctg gtgtagctgt agcaatagca atgggaggtc
     9361 caggagcatt agtatggatg tgtataatgg ctacattagg ttcagcaact gcatttgtag
     9421 aatctactct agctcaaata tataaagatg agcatgatgg gcagtataga ggaggacctc
     9481 catattattt tgaaaaaggt cttgggtgga aaaagtgttc agttttattt tcaatagttg
     9541 caataataag ttatacattt tttatgcctg gtacacaatc aaatacttta tatctagcaa
     9601 tgaatcaagc atttggattt tcaaaaatga caatagcagt cgcatcttct attgcattag
     9661 caataataat ttttggagga attaaaagga ttggtttatt tgctgaaaaa gtagtaccta
     9721 taatgggtgg agcatacctt attatgacat tagtaataat tataacaaat attagtttag
     9781 ttccagaagc tattgtaaca atgtttaaat ctgcatttgg atttggttca gtttttggag
     9841 gaatgttagg ttcagcagta tcttggggag taaaaagagg tatatactca aatgaagcag
     9901 gagaaggttc tgggacttat ggtgcagcag cggcagaagt aagtcatcca gccaaacaag
     9961 gattagttca agcattttct gtttatgtag atacattatt aatatgtatg gctacaggta
    10021 tcatgattgt aataacagga atgtataatg ttacaggtgt ttgcacaaca ctgccaggtg
    10081 tagaacctgg gccacaatat gtacagagtg caataaatac attacatcca caattaggtg
    10141 atatttttat agcaatagtt ttattattgt ttacatttac aactttatta gccttttcat
    10201 atatgatgga gactaatgta tcttacttag taactagaat taaagcagaa aaatatgaaa
    10261 agtacataat taacgtctgt agatttatgc ttatagcatg tgcagcaatg tgttgtttta
    10321 tagaaccact tacaagttgg gcattaggtg atatatgtat aggtgtatta acatatataa
    10381 atttaattgc catctttaca ctaaaaaaac cagctataaa ggcatattat gattatataa
    10441 gacagaaaaa gatgggaata aaaaggagcg atagaacttt taatcctata gaattagata
    10501 taagaaatgc tgagttttgg gaaaatagat acttaaaaga gaataagcat gagttaaatt
    10561 aaagttataa taaaatataa gaattactaa ataaacttag tgggaggtaa gattggtatg
    10621 aaagaaagaa taatacaagt ggcggattca aagaaagaaa aaattctagg gctatgtcaa
    10681 tctttatatg atgaaccaga aattgctttg caagaatata aatctgctaa aaaaatagca
    10741 gaatttctaa gagaagaggg ctttgatgtt gaggaaaact tggcaggtat ggctacagct
    10801 tttaaagcaa ccaaaaaaaa tggagatggt cccaaaatag catttatagc agaatatgat
    10861 gctcttccag gaaatggcca tgcatgtgga catcatttaa ttgcatctat gggagttgga
    10921 gctggaatag ctctttcaag tatactggat acttataagg gagaagtcag tataattgga
    10981 acacctgcgg aagaaactgg agatggaaag ccttacttga tagaacatgg tgtatttgat
    11041 ggctatgatg cagcaatgat gatacatcca aattcgaaaa cttgtgtgac accagaaatt
    11101 atagcaatag gaggattgga ctttatattt actggaaaag catctcatgc aggagctaaa
    11161 ccatataatg gaataaatgc actagatgca gtagtactac tatataataa tataaatgca
    11221 ctaagacaac aacttataga tggaacgaga atacatggta ttatactaga agcaggaact
    11281 gctgcaaatg taatacctga tatgggaaaa gtaagattag agataagagc aaaagaacaa
    11341 aattactttg atgaagtagt agaaaaagtg aaaaattgtg ctagaggtgc tgcaatagct
    11401 actggatgtg aacttgaatt ttatcacttt gaaccaactt gtcaaggatt aaatgaaaat
    11461 aaagttttag tagagatatt tacaaaagtc atggaggaat ttggaatata tgaagatgaa
    11521 caagtattgc taggttcaac agacatggga aatttaagtc aaataatgcc atgtatacat
    11581 cctttgatga aattttctga aaatggagaa gaattgcata cgaaagaatt tttagaagct
    11641 tccataaatc catatgcaaa agatagagta attgatggta taaaaatatt ggctttgaca
    11701 ggatttaatt tatttgaaaa ttcagagtta ttgaaaaaaa tgaaagagga gtagacttta
    11761 aacaaagggg acttgactat gactaataaa actgaaggta aaaagaaaaa attaacattc
    11821 ccagatgcat atgttttgat gataggtctt attgtatttg cagcgataat gacttatatt
    11881 gttccctctg gaacatatag tagaattgaa gatttaaata ctggaaatat gcttgttcaa
    11941 gctggaagct ttaaatatgg agagcaacat ccagttagca taatggatgt atttagagct
    12001 ataccaagtg gacttggaaa aaattctgta acaattttct ttgtacttat tattggagga
    12061 gcatttggta tagtaaattt tactggttca ctagatgttt taattggcag agttatatct
    12121 aaaagtcaag gcagtaaaaa aggtgagatt ataattacaa gtttagtatt aacttttggc
    12181 ttagctggtg gagttgtagg tatgtatgaa gaatgtattg cttttttacc aatattaatg
    12241 actctgtgca ttgctttagg atatgatgct ttagttgcag ctggtatttt attgttagga
    12301 cttgcatcag gttatggttc agctactatt aatccattta cagtagggct agcacaaggt
    12361 atttctgggt taccactttt ttcaggcatg tggtttagat ggatattttg gatttgtact
    12421 atgattttac tttcaggata cataattttt tattgtaaaa agataaaaaa agacccgagc
    12481 aaaagcttag tttcagatat tgattatagt cattggcaat tagatgagtc ttctataaaa
    12541 gaaaaattat catctggtaa catcagagta ttagttacat tctttggtgg gatacttgtt
    12601 ttgatgataa ttattgtaaa attttcttta ggtatgtcag atttatcagc ttacttcttt
    12661 gctttaggaa ttttatgtgg ggtagtttat ggaatgagtc caaataaaat tgcttctgca
    12721 tttgtaaaag gtatgcaaga gatggtttat ccagccattc tgatagggtt tgcatctagc
    12781 atagtagtaa tactagaaca aggagtaatt ttggattcaa tagtacatgg attatcatta
    12841 gttttaaatt atgttcctag aattttcagt ggtggagtaa tgatgattat gcaatccata
    12901 attaatttat ttataccttc aggcactggt caagctatgg taaccatgcc acttatggct
    12961 ccacttgcag atgttatagg tgtaccaaga caagttgcag ttttagctta tcaaatgggg
    13021 gatggttttg caaatggaat agttccaaca cttggagttc ttatggctgg tatatctatt
    13081 gctcatatac cttacacaag atggtttaaa tttgcatcta agataatact tatggagttg
    13141 gttttagggt ttatattttt aatgatttca gtacagatta atttaggtcc tttttaatgt
    13201 atttacgtaa tatgtttata gaattttaag gtaaattata ttgaggttaa atattttgaa
    13261 ttataatatg ttaggtttaa ttatggtttt tgaaataaag ggtgaacttt gtgaagttca
    13321 ctcttttaat ttgtagcaca aaatatcatt aatgattaca gctttggtga taaaattaat
    13381 ttcaagatat ttataggagg ggagtaatat ggagacttta aaaataagaa atattgaatt
    13441 gagtggtaca aattatgaga taggatatga attaggtaaa ttaattgcca atactccaaa
    13501 gatactagaa ggacaaatta ataaatctaa tgtagtaaca aaggaagaag agaaagagat
    13561 gttagagtta tttgataaat attgtccagg tcttaacgaa gaactgaaag gttttgctga
    13621 tgcagttcaa gtgaattgta atcaaatttt gtattatact atgacctatc ttaaacccgg
    13681 ttgcagtcaa gttgcgttag caccagaatt aactacaaat gggcatgtac tatttgcacg
    13741 taatttcgat ttttcacaca atatggagga ctttgtttta tgtaaaacga aagtaaaagg
    13801 aaaatatgca catataggca ctactgttat gcaatttgga agaggggaag gaatgaatga
    13861 atgtggatta ggcgtgagtc agtcatcatg tggtattcct gtaggtaatt cagttggttt
    13921 aagaaaacca gccgttgtag gattacagtt ttgggctgtt attagatatt tattagagaa
    13981 ttgcaaagat gtagatgagg cgttagaata tatagaagat atgccaattg catataatat
    14041 aaatttgtta cttgcagata agtctggaaa tattgcactt gtagagactt tagatggaaa
    14101 aaaaggagta aatagaatta atagactaga aaagcagagg gaacattttt tacactctac
    14161 taaccatatt catattgatg aacttcataa attagaacca caatcaatta aaaattctat
    14221 tcatagatat aaattaatta aagaatatat aaacaattct aaaaaagttg gagagaaaga
    14281 gttaatgaat ttgttgtcct caaagtatcc aaatggttta tcttgtaatt actataatga
    14341 tttttttggt actttaaaaa gtatagttat ggatttaaat actggtaaat ttaatatttt
    14401 atggggtgga ttagagagta ataactggga gagttactat ttaaaagacg acgttaaagc
    14461 tacaacacat ctgataaata taaacattga aaaggcacca tctgactttt tcgatttcgt
    14521 tgaataaaaa tgtgtttaat tagtttaaat aattatgctc tataaatcag ttaaaagttt
    14581 ttatttgtct tattgaattg gttataatat tttagtatag ttaaaaatag tgttacttta
    14641 aatatttaaa gattttaaat agaagagagg tgccatattg gattacttag agtattttga
    14701 aaaagctgta atttatattg aaaataattt acaagaaaat ataactgtaa atgatgtggc
    14761 aaaagagtct ggatattctt attatcattt aacacgctta tttaagtcta tgtttggtga
    14821 gagtgtagga agctacataa aaaaaagacg attagtaaat agcacaaaag aacttttata
    14881 cagtgataaa aaagtgatag atatagctat tggtagcggg tttgaatctt cagaagcatt
    14941 tagtagagct tttaaatcta tatacaaagt tagccctata gagtatagaa aaaatagaat
    15001 tgatgtattt gttggtaaca agaagaaatt agaattagac tttatgagac atcttatcgg
    15061 aaatataacg attaaaccag ttataaaaga aatagatgaa ataaagataa taggtataaa
    15121 agataaagtg atactagaaa ataattcatt acctgaacta tgggataagt ttagaaaggt
    15181 acaccaaatt gttccaaata ctttaccatc agagagagtt tttggaatct gtgaagcaac
    15241 atctgaaata cacctaatta gtgaaagtat ggagtttaat gaaataatag gggttgaagt
    15301 tagtagttat gaatcgattc caaattcatt tgtttcaaaa actattacag aaggaaagta
    15361 tgctgtattt actcatactg gtagcttaga gaatttagat aaaacctatg aatatatatg
    15421 gggtacttgg tttttaaact caaaagaaga gtttgataca agagatgatt ttgaagttta
    15481 tgatgaacga tttttaggtc ctaataatat aaattcacaa attgatattt atatacctat
    15541 aaaataatct ataagaaact aaaaaataat ttgattaaaa aatagatgct tgaaatagca
    15601 tctatttttt tatttttatc aagtttaaat aattttaaca ataaaagaaa tagaaagaag
    15661 ttcttaaatt tctaataaga atttagaata tagtcgaaat aaaaattata tatttctgaa
    15721 aattctaatt agtacaattt tttccgttgt aaaattgaaa aaagatgtat ttatttatca
    15781 aaaatattat attaaaatga tattaataaa aaaaacattt ataataatag cgtatagtaa
    15841 agaaaaaaga attaatttgt aaaatttatg gtgagtagta aaattaaaaa tttaaaaacg
    15901 ttatagggag gttataattt tatggaaaac gttattacag gtctaagtaa aggtgcagag
    15961 tggtttatag gtttgtttca gaaaggggga gaacaattta taggtcttgt ttcagggact
    16021 cttccaacac taattgtatt aatggtagct attaactctt tgattaagat aattggtgaa
    16081 gaaagagtca ataattgggc ttctaagcta ggaaaaaatt cttttacaag atatatttta
    16141 cttccgctag tatcagtatt tttcttggga aatcctatgt gttatacatt tggtagattt
    16201 ttaaaagaag aacacaaagc aggtttttat gatgcagcag tttcatttgt acatccaatt
    16261 acagggcttt ttccacatgc aaatgcagga gaactttttg tatggttagg aatatcagcg
    16321 ggtttgacta ctttaggtaa agaaactact acactggcat tatggtattt tatagttggt
    16381 ctaattgtaa tttttataag aggtatagta acagaaaaaa tgtatgcttt tttaacaaga
    16441 aaaaataaag tagcagataa ggcttaggag gtagataaaa tggatgaaaa taaaatatta
    16501 aaaatagaaa aaggaacttc aggttgggga ggtcctttat atataaaaaa agaaggcaat
    16561 agaaataaga tattatcaat gactgctggt ggtatccatg aagtaacatt aaaaataaaa
    16621 gaactactgg gttgtgaagt tgtagatgga tttaaaactg gagtttctga tgaagaagtg
    16681 gcagtggtta ttattgattg tggtggaact gctagatgtg gagtttatcc aaagaaaaaa
    16741 ataccgacaa tcaatgtaaa tccagttgga aaaacaggtc ctttagcaaa atttataaca
    16801 gaggagtatt atgtatcaga tgttagtcct aactgtataa gtgttgtaaa tggagaagat
    16861 atgcaaaaaa aatctcaaga aaataaaagt gaaaataaga gttctattag aaagcctgat
    16921 aattatgatg aggttaagtc aaaagcacaa ggagaatatg ctaaaaagaa tataatactt
    16981 tctattggtc aaggagcagg acaagtagta tcaaaatttt atgatgcagg tcgagatact
    17041 attcaaatgg taatgaataa tgtaatacca tttatggcat ttgtaagcat gcttatggga
    17101 attattttag catctggatt gggagattgg attgcaaaag tcatatctcc acttgcaggt
    17161 aatatcggtg gattattgat tatatcaata atttgtacac ttccattctt atcaccaata
    17221 ttagggcctg gagcagttat agcacaagtg gtaggaactc ttgtaggtac acagattggt
    17281 cttggagcaa taccagcata tttagcgctt ccagctttat ttgcaataaa tggtcaagct
    17341 ggatgtgatt ttgtcccagt aggattgagt ttaggagaag cagaaccaga aactgtagag
    17401 tatggtgttc cagccctatt ttactctcgt ttaataactg gaccaatatc tgttattatt
    17461 gcatatggag ttgcagtatt tgcattgaga taatatttaa tgtcaatata aggcttggaa
    17521 ttaattacta aaattgtaaa tataaattta agctagtcaa gattttttgt taatgaaaga
    17581 ctagctttta tactattaat tagctgtaat tatcgagtta gattaatact aaattttcct
    17641 ttattaaagt gaaattttat gtattaattt ggtttcaagt ttgtactaga atgaaatcaa
    17701 ggaggagata caaaatgagt gtaactgaga aaattccttc tattgaccac aagatattta
    17761 agatattgat tatgtgcagt aaaaaagagt ttgtgagtat taattcaata gcaaatgaat
    17821 tgaatgtcac aactagaagt gtaaggacgt atataaaaca attgaataaa gatttaggta
    17881 atgatatagc aataattaaa tatataaagg gtcaaggcta taaactggaa ataaaagatg
    17941 agcagatact caataagatt attgatataa atagaaaaaa tgtattttca ttaaattcaa
    18001 aagaagatag agtagagttt atactaaatt acttgacaga actagatgga tttattacac
    18061 ttgatagttt agctgatgag atgtgtgtag gaagaactac tttagtaaat gattttcagt
    18121 atgtagaaaa agttttggct tcatataatt taaacttaat taaaaaacag aatacaggta
    18181 tgaaattaaa tggaaatgaa cttgatatta gactgtttat attaaatcag ttgtataaaa
    18241 attcaaggaa ggatttcaat aactcaaagt attttaaagg aatcaaaaaa gaagaaatca
    18301 taaatttaga agaaaaacta ttgactttat ttaaaaaaaa taacttttat gttacagatg
    18361 aaatgttaag agaggttatt aactatatag tagttttagt ctatagagta aaagaaacga
    18421 agaaagtaaa ggactatgat gtaaagtttg atttactcaa atcgtatgat gagtacttta
    18481 ttgctaggga aataaaacat ataatatcag aaatgtttga atgtatttta aatgatgaag
    18541 aaattattta tttaaccata ccactagtga gtggaaatgc accagcatca gaatgtgctt
    18601 taaatagtag tagaattaat aaaaatattg atgagttgat ggaaagtata tttaatcaaa
    18661 tatatgttga tatgggtatt tttataaatg aggatgaatt aagagtagga ttgggatatc
    18721 atcttagttt tactttgaac aggctattat ttaatataaa gttaaaaaat gttttgctag
    18781 aagagattaa gcaaaactat atacttccat ttaaattagc acaaatagca ggtaaagtaa
    18841 tagaaaaaaa atataattta gaagtttcag aagatgagat tgggtatata gcaattcatt
    18901 tcagtggata tttagaaaga aatagtagta gattctattc aataaagaaa atagcaatta
    18961 tatgtagtac aggtctagga acagcaaaac tattaaaaat aagggtagaa aaactgatag
    19021 gaaataatcc taaaattgac actctttcaa gctttaattt gagaaatatt aatttagatg
    19081 aatacgatat agtttttaca acgattgatt tagacacatc taatataaat acaatagtat
    19141 taaaaataaa tacaatattt gatgaaaata aactaagaga acaattaaaa acagtactat
    19201 gcctaagaga aggaaatatt gatactacta actctacaaa tttactaata aataatttgt
    19261 tagatgaaga taaatttatg atattaaatg aaaagactat acttgattca ttagaaaaaa
    19321 tgatggataa tcttatggat ttgggatgta ttgatgataa gtttagaaaa aatatattca
    19381 atagagaaga aaaatctcct acagtatttg ataaaggttt attatttcca cattctgtga
    19441 atgaaaaatc agataaattt ttaatggcag ttggaatttt agaagagcca ataaaatatg
    19501 caaatagaaa cataaaaata attcttatga caatgtttcc atgtgaaaat aagatggatt
    19561 cagacttatt ggtaaaaatt tatgaagaaa ttttaaagat agggcaagat gtaaaattga
    19621 caaataaaat aagtaagtgt agaagttttt tagaatttaa aaaggtatta cttaaaaacc
    19681 ttatgtaact actgtacaga atctatagtt attgtacaga ttaaaagaat aatgtgattt
    19741 ttggaaggtg tataaatatg aaagtactag tgattttatt tgctgcttat attttgaata
    19801 ccatacttat aatgaagcag aataagttgt attttaaaac tttaaataga gctaaaaaaa
    19861 agggtgatat agtgtccaca ggcaaaaaga aaagctattt ttctaaagga agtatagcca
    19921 ttatatcttc agattcaaat ggatttataa agtttggaga gattttaaaa ggtcgtacag
    19981 taatggctaa gtttaaagag attgaagaca tagaaggatt agatatatat agtgcagagc
    20041 aaaaatttaa aaatgaagaa agtattgtac aagctataaa atttataaaa gaaaaaataa
    20101 atgtttcttt taattaactc aatataaata taaattatca ggaggaatgt catgaaatat
    20161 gaagttaaga taagtggaat aggaagttta gttaaagagt taatggatga aagtaattgt
    20221 cttattatat atgatgaaac cattaatgat gacgacttaa aggatatatc tgtaattcat
    20281 tcgatatcga cattaagaag tgatgttgaa ataggggata cacttactat aggaaataga
    20341 gattattgta tagtttcagt tggtgatatt gctcaaaaga ctcttagaga aattgggcat
    20401 tgtacaatca aatttgatgg aaaaaatgaa gtaaatttac caggagaaat tcatgtggaa
    20461 ataggaaatc cagatataac tattggagat ttaataacta tttcttaatt tgaaaataaa
    20521 attattataa caggaggaat tggtatgtta gatttaaaca gaaaacttgc aaaattggaa
    20581 gaggaaggta aaaagataag agtagctctt ataggggctg ggcatatggg aaatggaatg
    20641 gtaagccaaa tggcaaatat gaaaggtatt gaagcttcta ttgttgtaga tataaatttg
    20701 gagttggctc ataaagcttt tactgatgca ggaatagatg aagaaattat agacaatgta
    20761 acaaatgaaa atgatgcaga aataaaatta caagaaggaa aagtattgac atgtaatgat
    20821 tttcttgtag cttgtaaaac taagtcaata gatgtagtta tagatgcaac tgggggtatc
    20881 gcaattggtg cagagatagc attaaactct attttaaata aaaaacatat agttatgtta
    20941 aatgctgaaa ctgattgtgt tgttggacca atacttaaaa aattggcaga tgatgctgga
    21001 gtaatattta caggttctgc aggagatgag ccaggtgcag taatggagtt atttgatttt
    21061 gcagatgcaa tgggatttga agttagagtg ataggtaaag gtaaaaataa taaattagat
    21121 ttagattgta accctgatac agttagagaa gaagcagaaa taaaaggagc ttcacctcat
    21181 atgatagctt cttttaaaga aggaactaaa acaatggtag aaatggcttt aatgtgtaat
    21241 gcaactggat ttgtacctga tgtaagaggc ggccatggca ttgaagctac tgttaatgaa
    21301 gtacctaaga aatacgcatt aaaaagcgaa ggtggagtat tagataacta tggtgtagtt
    21361 gattttgtaa atggtatagc acctggagtt ttcgtagtag tagcccataa attaaaagca
    21421 gttaatgatg aattaaaata tttaagtatg ggtgatggac ctaattacat attatataga
    21481 ccatatcatt tatgtagctt agagactcct ttatcagcag ctatggcagt tttagaacat
    21541 aaagctacaa tagttcctaa agctggatta gttgcagaag ttatgactat agctaagaaa
    21601 gatttgaaaa aaggtgagta tatggatggc tatggagcat atacatgcta tggcactata
    21661 gaaaaatacg atgtagcaaa ggctatgaaa gctgtaccta ttggtttgat aagtaaaaag
    21721 actaaagttg tcaaagatat taaaaaaggt gaagttataa cttacgatat ggtagagata
    21781 gaaaaagata ctactctata tcatttaaga caattacaag aaaaaatatt tgggtaagat
    21841 ttgatagtaa tataaatgga tattaacaaa aagggttgat gattattttt aaatcaaccc
    21901 ttttaaattt ttgtatattc ttgttaggat actttcttta gaattatatt ataggttatt
    21961 tgtagttata aaaattattt ttaattagtt ctgcaatttt atattcatat taaaataata
    22021 ttattaaaaa ttttaatata aaatgaatta aaatgaccaa ttatgtatta taatattaac
    22081 tgtaatacta atatagttct attaattaaa gaaatatccc ccattaatat ataataaata
    22141 tctttaagcg agagaactta gtaaaaaata tatcgtattc aataaaaaat ctgtttacag
    22201 aatggtatat atagttatat aatatactat ataagatgcg aaaagataaa aagtatagca
    22261 caatgaaaga aggtgattat tattcagctt aatgaaagac aactaaaaat tatagatata
    22321 gttaaggaaa atgaaccaat aacgagtgaa agtattgcct ccagcttgaa tgtgactcgt
    22381 gctacactta gatctgattt agctatatta acaatgacag gaatattaga cgcaagacca
    22441 aaagttggat atttttattc aggagttagt gaaataaatt taattggtaa gagtgtaaaa
    22501 gaaaaaacag tagaagatat aatgagcatg cctgtactag ctaagaaaga cgaaagtata
    22561 tatgatgtaa tagtcactat gtttttatct gatgtaggga gtatagttat tatagatgag
    22621 aatgaagagt tatgtggagt tgtttccaga aaagacttgt taaaagcaac tataggaggt
    22681 tctgatataa ataagatgcc aataggtatg ataatgacaa gaactccaaa tgtagtaact
    22741 ttaactaaag gagcaagtgt tttattagct tcaagaaaaa taatagaaca tgaagtagat
    22801 tcgattccaa ttgttgaata taagggagaa gacaaaaatc atatgagagt tgttgggaga
    22861 atatcaaaaa ccaacataac taagctattc ttagaaatag ttgacaatta aggaggtatg
    22921 ctggtgaaaa acctaattat atatgcagtg tcagattcag taggggagac tgcacaacaa
    22981 gttgcaaaag catgtatgtc tcagttttat gtgaatgaaa cttatgaaat aaaaagattt
    23041 ccatacatga ttaataaagg agtactactt gaaactttgg agaatgcaaa agctgaaaac
    23101 gctttgattg tatatacatt agttgatgaa gaattatgca gtattgttga aagatattgc
    23161 gaaagagaag gacttagttg catagactta atgacagata tactaagaga aataagcaag
    23221 agaacaggaa gaaaacctaa aagagaagct ggtataatta gaaaattaga cgaatcttat
    23281 tttaagagag ttgaagccat agagtttgca gtaaaatatg atgatggaaa agaccctaga
    23341 ggtattcttc aagcagacat aattttagtt ggaatctcaa gaacgtctaa aactcctttg
    23401 agtatgtatt tagctaataa aaatataaaa gtagctaatg ttccattagt tccagaaata
    23461 ccaattccta aagaagtgtt tgagatagat actaagaaga taataggtct tactaattca
    23521 cctgaaaagc tgaatgagat aagaactcaa agattaaaag ccttaggttt atctagtaaa
    23581 gcaaactatg ctaatttaga aagaatactt caggaattag attattcaga agaaataatg
    23641 aaaagaattg gatgcccagt aataaatgtt tcaaataagg caatagaaga aacagcaggt
    23701 ataattttag acataatgaa agaaaatggt ctaaagatat acaaagaaat agaaatttaa
    23761 taatgtctat taataaaaat gatataaatt aaaataaaaa gattaatggg ggatttaaca
    23821 atggaaacta agtatgttta tagttttggt gaaggaagca aagacatgaa atctttacta
    23881 ggaggtaaag gtgccaattt agcagaaatg actaagatag gcttacctgt ccctcctgga
    23941 ttcactataa caacagaagc atgtaatgat tattatgtta acaatgaaag tataagaaaa
    24001 gagataataa aagaaataga ggagcattta gctactttag aaaaagattt aaataaaaca
    24061 ttaggatgca ataagaatcc attattagta tcagttcgtt ctggtgcagt attctctatg
    24121 ccaggaatga tggatacaat tcttaaccta ggtcttaatg acaacagtgt tgttggtcta
    24181 gctgaggcta cacaaaatga aagatttgca tatgatagtt acagaagatt catacaaatg
    24241 ttttctgatg ttgctatgga agttccaaaa tataaatttg aaaatgtatt agacagagta
    24301 aaagaagcaa aaggatatac agttgataca gagcttacaa ctgatgattt aaaagaaata
    24361 gtaaaagaat ttaaagcaat ttacaaaaaa gaaataaaaa atgatttccc acaagaccca
    24421 aaagagcaat taatgcttgc aatagaggct gtatttagat catggaataa tcctcgtgca
    24481 atcgtatacc gtaaattgaa tgatatagct cataacttag gaacagcagt aaacattcaa
    24541 tcaatggtat ttggaaatat gggagaaact agtggtacag gtgttgcatt tactagaaat
    24601 ccagctacag gagaaaataa attatttggt gaatttttaa tgaatgcaca aggtgaagac
    24661 gttgttgcag gtataagaac tcctcaaaat atatcaactc ttgcagacgt aatgccagct
    24721 gtatttgatg aatttgtaaa aattactcat atacttgaag gtcactataa agatatgcaa
    24781 gatatagagt ttactataga aaatgaaaga ttatatatat tacaaactag aaatggtaag
    24841 agaacagcag cagcagcaat aaatgtagca gttgatttag ttgaagctgg aataattgat
    24901 gaaaaagaag ctataatgag aattgaacct aatcaattag accaattatt acatccaaaa
    24961 tttgaagata atgcgttaaa agaagctaag gttatagcaa aaggtttacc agcatcacca
    25021 ggtgcagcaa gtggtaaagt ttatttcaat gctgatgatg tagtaaaagc aaatgaaaaa
    25081 ggagaaaaag tagttttagt tagactagag acatctccag aagatataga aggaatggtt
    25141 aaagcagaag gaatccttac agctagaggt ggaatgacat cacatgcagc agttgttgct
    25201 agaggtatgg gtaaatgttg tgttgctgga tgtggagaaa taaaagttga tgagtttaat
    25261 aaagaaataa gagcacttga tgatgtagtt ataaaagaag gagaatatat ttctatagat
    25321 ggttctacag gaaatgtgta cctaggagat gttaagaaaa cagaagtatc tttaactgga
    25381 aactttgaaa aattaatgaa ctgggtggat aaacacaagt gtatgatggt tagaactaat
    25441 gcagataatc ctagagatgc tcgtgcagct atagaatttg gtgctgaagg tataggttta
    25501 tgtagaactg agcatatgtt ctttgatgaa gctagattgc cagcagttag agaaatgata
    25561 ttatctaaca cagtagaaca aagagaaaaa gctcttgaaa aaatattacc aatgcaaaga
    25621 gaggattttg tagagttatt taaagttatg gatggaaagc cagttaatat aagattatta
    25681 gacccaccac tacatgagtt cttacctcat gatgatgaga ctatagaaga actttcaaaa
    25741 tctatgggaa taaaagtaag tgatattaag aagagaatag ttgatttaga tgagtttaac
    25801 ccaatgcttg gacacagagg ttgtagactt gcaataactt atcctgaaat atgtgtaatg
    25861 caatctaaag ctataataca aggtgctata gaagcaatca aagcaggggt taaagtttct
    25921 ccagagataa tggttccatt agttggagaa gtaaatgagt taaaaataat aagaaaaatg
    25981 atagtagaaa ctgttgatgc tataataaaa gaagaaggcg tagaagttcc ttatactgta
    26041 ggtactatga tagaaatacc tagagcttgt ttaactgctg atgagatagc acaagaagca
    26101 gacttcttca gttttggtac taatgactta actcaaatgg catttggata ttcaagagat
    26161 gatgctggta aattcttagg tcaatatgta gatgaagaga tattagaaaa agacccattc
    26221 caagtactag accaaaatgg tgttggtaag ttagttaaga tgggagctaa attaggtaga
    26281 gaagttaaac cagaattaaa attaggaata tgtggagagc atggaggaga accatcttca
    26341 gtagagttct gttatagtgt aggacttaac tatgtatctt gttcaccatt tagagtgcca
    26401 attgctagac ttgcagcggc tcaagcatct ataaaaaatc ctagataata atagaatgta
    26461 aaatatgtaa ctaaataaaa ataatatccc ctattgttca atgtatcaaa tctagtattt
    26521 gtaagttgaa tataggggat ttttattata aaaatttaac ttatatggtt gtaagtgaaa
    26581 cgtatttaat tatattgcat atattattgt agagagaaat tttaactatt aattaaattg
    26641 agtttactgg aggggataaa gttgacaaag tgtcctaaat gtggaaagga agtatcatca
    26701 cgtccaggta gtatatgccc acgatgtgga tttaaggtag cagatgagag tctaaaaata
    26761 agatgtccag aacctagttg tagggctttg gtatctagga aactggatta ttgtcctaaa
    26821 tgtggatgca aacttagagg atataatatt tctgaatttg ttaacatggt gagatgtaaa
    26881 atagatgaga catttgataa aagataatta aatttaaagt taaacttttg agggtgtctc
    26941 aaaatgaact ttttagttta tgagacactc ttttttgtat gaaatcaaat atatttttat
    27001 catttaaata gttaaaaaga ggcttatctc cattttgaga tagcctctat aaaagtatac
    27061 agttttataa gtaaatatat ttttgctaat ctatttctat tatttgcctt atgaatcttc
    27121 catagctaaa gtcataagtg tgcatagcta ttttttaatc aaatgtatgt taaagtaatc
    27181 tttctattta ccagaattac tttccagtat taagtatcca aggtttctct ataccatttt
    27241 ttagtgagtt ataattcaca ataagtgtgt catagttatt tttagcatct tcattgctta
    27301 caacttgttt tttataatca gttagagtaa ttaatcctaa atcatatctt aatttagtat
    27361 tttttaattg tttttctgat agttcaagtt gttttttagt aatctgaatt gtatcttcta
    27421 aagcaagtaa ttgagcataa ctgtcaatta atcctttttt aagagctttt ttattgtctt
    27481 ctaacgttac tagaccattt tcagtattgt atttttgttg aagataattc gcataagtag
    27541 taagaccagc agcataagtc tgtctttcaa gattgtattc ttcaacttct tttttatatc
    27601 tatcataatc ttttccatac ttatccataa gaaccttgta ttcatcatca gttagattac
    27661 cttgttctgg ttttgtagga gcaactggtc ttgtaagatt aggtctatct ggtaaatctg
    27721 ctttgttctc atctttatca ttaaaacttt cttctgtacg ttctaaaatc aattggtcgt
    27781 attttaaata ttcattaacc ttgccttcca tatatgaatc aactgagcca cctactctga
    27841 aagattcaaa tctatattct ttatctaatt gataattatt taaatctata ttagtcaata
    27901 atttaaaata gtcttgatta ttttttagtt cttgaagctt agctttttga gtattttgta
    27961 gtgtttgaag ttcaagttca gctgactcag tttctaaaga tgttactagc cctaaatctt
    28021 tttttaattt catatcttta atttctttag tttttatctc aagattattt tttatcttat
    28081 ctaactcatt ttctcttgaa actaaatcgt taaatttatt agtaatatca ttggctattt
    28141 ggtcctccat aaaaccttta gcctgttcac tttgattttt aagaagtcca atttggtcat
    28201 atggaaatga gttgtcactt ccagtaaaac tatcaaattc atcttgcact tctaactttt
    28261 cttttaacat ttttatttct tctgatttca tttttaattt ttcactattt ttaagtgcag
    28321 cactaacagc ttctctagca gttaaaattt ccttttcaga tgttctttta gttgagtcac
    28381 tcacaatgga attatcaact ttatttatag aagaagtact attatctgca taaacgggta
    28441 ttagattagc tgttattata ccaacgccac agccaattgc aactattttg ctaacttttt
    28501 tattcaatac aatcaccctc cattctattt aaactttagc ttttaatttt ggtttcttta
    28561 ttatttttct ttttatatca cctattttat ctgttatttt accaaatatc ttaggcattt
    28621 tgtctgaaaa cttattttcc catttatcaa atatcaagta tatagtaggt ataagtacca
    28681 aagttataag tgtagatata gtcagacctc ccattataac tattgccagt ggttgcattg
    28741 tttctccacc ttcaccaaga gatagtgccg ttggtaacat acctaaaatt gttgttgctg
    28801 tagtcattag gactggtctt aatcttgctg cacaaccaat tgaaaccaaa ccaattaaat
    28861 cattattacg atttgttttt ctaagttgct ctatgtagtc aataagaact ataccattgt
    28921 taacaacaat acctataagt aagattatac ctagcatacc tacagtactt aaactttgtc
    28981 cactaactag aagagaaagc acaactccaa cgaatgcaaa tgggacacag aacataatta
    29041 taaatggttt actaaatgat tcaaactgag ctaccattac catataaact aatactatag
    29101 ctatgagcat tgaaaatcca agactcgcca tagattcatt catcatctct gtttgaccac
    29161 caacaccaat agaataatct ttaggaatta ccattttatt cgttttttct agtgctagtt
    29221 ttgtagcagt accagcatct aaattgtcaa gtgtagcagt tatatttaca gagaaatttc
    29281 catcagttct agatatagac tgtaaaccat ctgccatttt tatatctgaa aaagcaccaa
    29341 gaggaacttc ttttccagtt gtagagttta cttttaattg ttttatgtct tctagattat
    29401 caatactatc tgctttaaat tttaaattta catcaacctt gtaatcatca atagtggcag
    29461 tagtaactga atcaccattt attgctgtac gcagtaatcc tgctatttca gcagtgttta
    29521 taccatattc ttgagctttg tgtttgtcta ttgtaaattg agcttcttgt gttgtatctg
    29581 taagagaagt ctcaacattt ctaaatcctt ttatagagct gaattgtttt tcagcttctt
    29641 ttcctaatat tttcaataca tccaaatcag ggcctttcat ttctaatgtg aaatctgctc
    29701 ctgaagttcc acccatgaca ctactatttt gactaacatt tattttacag tctgggacag
    29761 tggcaactct atcaattatt tctttttcta cctcatcagt acttctcttt ctattttttt
    29821 gtgattctaa ttcaattgct atatttgctg tattattatt tgaatctgat gtcaaagttg
    29881 ttattaaagt tttaatctct ggaatatctg aaactttttt ttcagtcata gatacatagt
    29941 aatcattaga ttctagacta agaccttttg gaagttctat agaaatagcc agttcacctt
    30001 tatctgcggc aggcataaag tccataccta taaagctcat tccaaataaa gaagctataa
    30061 aaataagtaa acttgatatt actactaagc gttgatgtct taagcataca cttagtaatc
    30121 ttttatataa ctcacttact ttatcaaata aaggagtatc tttttcttgc attttttgac
    30181 tattcttgcc tctacttaat tttgcaaata cactagggac aagagtaatt gcacctatga
    30241 aagagaaggc tagggaagct attagtgttt tacctaatgc accaaaggtt attttggcta
    30301 taccatctgt aaacataata ggtaaaaata ttgctatagt agtcaatgtt gatgcaagta
    30361 ttgcatttgt tacagttctt gttccttcaa tagcacaatc atcaatactc aatctaccgc
    30421 ttttcctata tttaaatata ttttcaatta caactgtggc attatcaaca accataccaa
    30481 ccgaaattac cagtgaactt gcagtaataa gatttaaact ttcaccagta aagtagagaa
    30541 ttgctatagc acctattata gaaattggta ttgcaatcgc aacaaccagt gaagctctta
    30601 cacttttcaa gaaagcaaag attacaataa atgcaataac agaacttata agcaagttgt
    30661 tcattacact gtttattgat tcacttatgt atgaacttgt gtcgttagca attttaattt
    30721 taaattgggg attttcttta tttaattcat ccacatattt gtatgcactt tgcataactt
    30781 ttacagtatt ggcatcttgt tgtttagaaa tatctattac caaactgtct tttccattgt
    30841 atctgtaaat actatctttg tctgcatatc cataatctac actacaaaga ttatctaatc
    30901 taactgtatt tccacctttt acaggaattt gaatctgttt tatatcatct agcgattcca
    30961 acttatcaat tgctcttaaa actattttat cttcaccttg agtaattgaa ccataaggga
    31021 atgttttatt actagaggat agtacacctt ttatagtgga taaactaact ccataatttg
    31081 aaagaacagc tgggtcagct attacattaa cctgtgcttt ttctccacct ttaaggtctg
    31141 ctgatgtaac accatctatg gattctattt taggttgaat cacatcttca gcatattttc
    31201 ttaatgcttg tgaactattt tcatttcctc cagatataac aagttgacct atagcttgtg
    31261 cattcatatc caactttaaa acagttggtt tagctgcatc atctggaaga ctagtttgta
    31321 atgcatcaac tttagaccta acatcattca ttatttcatc taaattagtt ccaaattcaa
    31381 attgagccac taccatagaa acactctctt gtgaacttga tatagtagat tttacatttg
    31441 aaacagctga taaactttca tcaacttttt gaccaatttg ttcatcaaca tcttgaggac
    31501 cagcacctgt ccaagtagtc atgaccatta caacgggtat ttctatatct ggcatcagat
    31561 ttattgacat tttcttatat ccaataccac caaaaactat taatactaaa aataccatta
    31621 taattgtgag aggacgttta acggaagttt gtgttaaatt catagcctat ttctcctttt
    31681 ctacaggaaa tatcttagtt ccatcagaaa taagacttat ccccccaata acaactgtat
    31741 ctttttcact tacaccactt ttaatttcta ttttgtcctc tgttacaatt ccagtttgaa
    31801 ctaatttttt ctttgctata ttatccttat ttgctatgta tacatatttc tttccttttt
    31861 cttcaaatat agccttttta ggtactgtaa cggcaccatt ttctttttca acacttaagt
    31921 ttacttgggc agacattcct gctttaaatt tgttgtttgt gttattaaca agcactttaa
    31981 taggatataa agatgtctgt gggtcaacta ctgaaggtac ataatctatt tttcctaaaa
    32041 ttctttggtc ttcaattata acttctacat ttccatcctt tttaaattta tctatatctg
    32101 attctgctac atttaaatta acttctaata tgttaggatt agaaataata aaagctggtt
    32161 gtgattgtgt tatcatttct tttgcatcaa aatttttggc tgttattgta ccatctactg
    32221 gagctgttaa tgttaattta tctaaattac tcatagctaa attatatgat acttgtgctt
    32281 ggtcaagttg ttttttagca agagctttag cttgtggtat actctttgaa gttactgtat
    32341 cgtatgatct ttgagcagaa tctagttgtt gctttgattg ttctaaagca aattctattt
    32401 ttttaaattg gtctaaacta attacttcct gctcataaag aatcttatta ttgtcataat
    32461 tcctttgaga ttcatcatat tgaatctttg cattatcaag tgctgttttt gcttgattta
    32521 cttgtgcttc taatgaacca cccgttgtac ttgaataact tgctttagcc aaatctagtg
    32581 ctgctttact ttgttttaca ctattttcta gatctggact gcttatactc aataattcat
    32641 ctccctttct tacattttgc ccaagtttta cataaacttc ttgaactgtg ccaacagtct
    32701 gtgcagtaac agctgtttca tctttaacct ttgtagttcc tgaaaaagca tttgtatttt
    32761 caatctctcc tcctactgct ttttgaacag aaactgctat tggtttctca ggctcaggtt
    32821 cttctgtttt tccacatcca actaaaaaca gtgaactaca cattaagaaa actattaaat
    32881 atcttttcat atctcctcct attatatatt gcacactaac ttgttgtaga atttaaagtg
    32941 tctcataatt caagtttatt tttaggctaa ttaaaaaact ttcttttatt ggcaatttat
    33001 aattctctaa tttgattata aatttataat tattatgagt caataacttt ttcttgtttt
    33061 aaatttgtta atagtttata atttatatta tataagtaac aaatgtttta ttacatcatt
    33121 tattgaaggg atgttacaaa tatggataat aacaatatac ttaaaatagc agactctttt
    33181 ttagactttt tatttgtgct tgaaaataat atatttagag aaagtgattt gttaaaaaaa
    33241 tttcaaaata actctgatat aatgaaagcg tattttgaag aatgtccaat ggctccatca
    33301 catgctaagg taattcttta tctcatgaca tcaaattcat catcaatatc tcaaatagct
    33361 tctaatttag gaattttaaa atcaaacatg acaccgatta ttgacagatt agtggaacat
    33421 ggtttagtaa ataaatttcc tgacccaaaa gatagaagga ttcttagggt tgaattaacg
    33481 gataaagcat ttgaattatt tggcgcagta aaagctattc tcaaagaatc tctagtaaaa
    33541 aaattatcta atctttctga ggaggaacta actttattag atgaacatac attaaagtta
    33601 tcagaaatag taaagaaatt aggttagcat gtggttgtaa aagtcattat taaaaaactt
    33661 aaaacttcat aagaaaagaa atagcagtag tataatatag aatattatac tactgctatt
    33721 tcttttctta tgaatattta gttatcaaac tctattttcc aattgaaata gccagtatct
    33781 ggatttttat tatactttaa taaagcatca aatttattac catttttagc agttaaagat
    33841 tttactttag tttcaccttt ttttaaaata tttttgacca ttgttttgtt aactttcttc
    33901 ttataaaggc ttaaatactt gtcatttttc caaataacaa atttacattc tttatgattt
    33961 ttacaagcaa agcctttgtc aaattccaat acatcacctt gacaaacagg gcatttacca
    34021 agaggttggt tttcatcacc atttttagat tcttttttgt tgttagaatc ttttgatata
    34081 gcaacttctt tttcagcatt agttgtatct tttttctgtt ttttctcttt tgttttagta
    34141 aattttttag tttttgaatc gaaggtatat tcttctgtgt ttatattttt tgaagcatct
    34201 tgttttataa tattgacatt ttgatatata aaactaatga tattagtaag gtattctttt
    34261 cttgtatact ttcctttttg aatatcactc aaactttttt caagtttccc ggtataatct
    34321 acatcaaata agtctttaac aggaaaaatt tcaactaaat ttttcccaag gtctgttata
    34381 gaataagatt ttcctttttt ctttacatag cctacttgat ttatcttctt taatacatca
    34441 gcacgtgtag ctgatgttcc aatcgaatat ccggacaaca ctgttgtgtc ttcttcaggc
    34501 acatttttac cacaattttt catagccttt aaaagagtgt cctcagtata cggtttaggt
    34561 ggagtagttt gcttagttaa tggttttatt tctaacacat ctacaacatc atctttattt
    34621 acaagtggaa gtaaatcgtt tttttcttcc ttattatata cttcaagata tccttttgat
    34681 ttaagcacct taccttttgt taagaaagta caattatcta cttcagtctt aatttctgta
    34741 ttctcatatt cagcaggagg cataaagttt gctatgaatc tatcttttat tgcatcataa
    34801 actaattgtt catccttaga taagtttttt ggaattatat aagttggaat tatagcacta
    34861 tgagagtcta ccttagaaga atcaaagact cttttagttt tagaaaattt aattttattt
    34921 tcatattcaa gaccaacctt taatttatct agagtttgag aagcttttga agccaaactt
    34981 tcttctaaga aaatagaatc agttctaggg taagttatgt atccaccctt accattaccc
    35041 tcataaagag attgacagac atttaaaacc ttatcagatg taaaattgga atacttagaa
    35101 gttatatatc cttgaagtga tgttaaacta aaaagttttg gtgcatattc ttttgacata
    35161 gtaacttttt tatctagtat tttaccagtt ttagatgcaa ttgaagctat aattttattt
    35221 gcatcctcaa gtgtatcaaa tttactttct ttgcccttaa tatatttacc tttgtattca
    35281 ccagtttcgg ctttaaaatg accctctatt tcataataag ttttaggaac aaagtttagt
    35341 atttccatat ccctatcata gactaattta actgttggaa gaattaccct acctatgttt
    35401 aatagtttcc catttccata tttcagtgta gcaacagaag tgaaatttat tccaatcaac
    35461 caatcagtaa taagtcttgt atatccagca gcttgaagat ttctcatctc atcttcgtcc
    35521 tttaagtttt ttatacctct tgtaatgtct tctggtgtcc attcatttac taagattctt
    35581 tttactggtt ttttattttt tgcaagtaaa aatattaaaa atgctataag ttctccttct
    35641 cggtcattat cagtagcatt tattacatat tccacatctt ttctattcaa aagctttttt
    35701 acagtgttga attgtttggt tttagaacta tcaattttaa atttaaattt atcctcagga
    35761 ataaatggga aattgttcat tttccaagag ccagagtatt tatctttatc ataatccttc
    35821 atatcatata atgatactaa gtgtccaact gcataagtaa ttatataatc atttccttca
    35881 aagtaaccat cttgtcttgt ctttgcacct aaaaatgatg ctatagtttt tgccacagat
    35941 ggtttctcag caagtacaag tttcataaaa aatcctcctt taaaacacta ataattatat
    36001 taccacaaaa aaataaaaaa cttcaagagg tcgaaattta agttataata tttatagaaa
    36061 gttgaaagga gaaataagat gtacacttta aaagtaaaaa aaataaatga tgatgctata
    36121 atacctaatt tcgctcataa aggtgatgcc ggtatggatt tgtattctat agaggaggtt
    36181 gtaatacctt ctggagagac taaacttatc aaaactggga tatgtataga acttcctact
    36241 atgacagaag cacaggtaag accgagaagt gggcttgcct taaagcattc tgttactgta
    36301 ttaaatacac caggaactat tgatgaagga tatagaggag agcttaaaat tatattaata
    36361 aatcatggta aaaatgattt taaggttgaa aaacatatga aaattgctca aatgataata
    36421 aaacctatct atgatattaa catagaagaa gtagaagaat taagtgactc tgaaagagga
    36481 aaaggtgggt ttggttcaac tggattttaa aaagttacaa aaaagttaaa aaatatagct
    36541 attttaaaaa aaagcaaaat atggctatat tgctaaatta caggctgtta aggattaaaa
    36601 tttatacatg gtaatttatg gtaaacaaat attactatag acaaatagtt acaaatttgt
    36661 aataatatta atataaaaga aataattgat attttaagag tgtcaattat ttcttttata
    36721 ttttgaaatg aaataaagct agtagaaaag aggagatgag tggaaagtta tgaattttaa
    36781 tcaaaagaga atagcagcta gtgtaatggc aactgcgata ataataccta ctatggggaa
    36841 tttagcatat gctaatgagt ctgaagtaga aagtgtgagt atagaaagca gaacaataac
    36901 agggaatgca gtaaatttta gaaaaggacc aggtacaaac catgaatcaa tggggaaact
    36961 ttacaaaggt gataaagttg agtatgtagg aaaagatggt tcttgggtaa aagttaaata
    37021 taatggaaac acaggttatg tgcatggaaa ttatgtagca ataaatagcc ttggaagtag
    37081 taatgaaagt agtgatactt cagttaagtc gacaaaagtt gtaacagcaa aaggcttaaa
    37141 ttttagaact ggaccaagca caagtagttc taaaatatca acactaggat acgggacgga
    37201 agtaggatac atatctgagt caaatggatg gtcaaaaata agttctaatg gtagagtggg
    37261 ttatgtttca agtaaatatt taggaactag tgtaaatgac tctacaagtg aaaatactgg
    37321 aaacagctca aatgacattg taaaaggtac aaaggtggta acagcaaagt cattgaacct
    37381 tagaaccgga ccaggtacaa gtcattctaa aatagctaca ttaagttatg gtactgaggt
    37441 tggtcgtatt tctgaaaatg gagggtggac aaaagtaagt tatggcaatc aaacaggata
    37501 tgtatcaagt caatatcttg ctgaaaaagg ttctgttgat acttcaattc catcttattc
    37561 gactaattct ccaagccaag gagctgaaag tgtaataagt tttgcaaaga cactacttgg
    37621 aaaaccatat gtgtggggag cagaaggtcc aaatagtttt gactgttctg gattcacaca
    37681 atatgttatg aaaaagtctg caggagttag tataccgaga gtatctagag accaaagcaa
    37741 gtatggaaca tatgtaaata gaggagacct tagaagtgga gatttaatat tctttgatac
    37801 acaaggttca aataatggtt ctgtaagtca tgttggaata tacataggaa atggagatat
    37861 gatacatgca tcttcaggtt catcaaaaaa ggtaacaata tctaatataa atagtagtta
    37921 ctattcaagt agatatgtaa atgcaagaag agttttataa ttatttttta ttacaaaacc
    37981 taataaacag atttttcttt attgcttata atatgaaagc aggtacaata ttgatagtaa
    38041 tgtatgttat aataaatatt actatttgat ttgtacctgc ttttttattt attttctctg
    38101 tttatagaaa ataaattata tttatatttt ttataaattt tgacacaaca gtaaattata
    38161 aattatcaaa taatagtagt ttatataaat aaaaatttta gaacattttt tgagattctt
    38221 ctaactcgta agcgtccatt aaagcttcgc caaatctttg atagtgaatt atttctcttt
    38281 gacctaagaa ttttagtaca tctataacat caacatcatc tgttaggttt ataagttgat
    38341 aataagttgc aagtgctttt tgttcagctg ccatatcctc atgtaaatca gttacggggt
    38401 ttgacataac tgctataggt cttacatcaa atgggacacc atttgaatct gttggataaa
    38461 ttccatatcc attttgtgca tagtttgaac caagacctgc agcttttaac tcttctgggc
    38521 ttgcatcaga agtcaactga taaaccatag tacatataag ctcaacgtga gctagctctt
    38581 ctgtaccaat atctgttaaa agtgcacgca tattaccagt aggcattgtg tatctttggc
    38641 ttaaatatct taaagatgca gcaagttctc catttggtcc accaaattga gttataagaa
    38701 atttagccat tctagggtca caagttttta tattaactgg gtgttgtata gttttctgat
    38761 atatccacat gaattttcaa tcctccaata cttgatgtct aataattaaa ttctctgtcc
    38821 caaggccaag gttggtcagc ccattgccaa gggcatctac ttggagcata cccaaagtta
    38881 gttaaaggac catatttatt ttcgtaagca tatctagctt gcgcaaattg attacataat
    38941 gaattataag tgttgatagc atttttatca tcagggtgat tgtctaaata taagttcata
    39001 tcaacacatg caaaagatgt ttcctgaatt tttctcataa gttcagctct agatgagtct
    39061 ttcattatct tctacctcct ctatattttt ttggcttagc atataattct ttgttgtaca
    39121 tttcagattc tagtaagttt agttctggaa atatagttcc aaattttaat gcatcagaaa
    39181 ggcagtacat ttctgtaaaa atttgattat taatgtatgg tctagccaaa gatggaccac
    39241 aatttttttt gatatctcta gtcttatttt ccaagatgaa aacctccttg ttgtaaatag
    39301 ataggtaact ctatctagtg tataatattc aatcgtttaa aaatcgttac taataataaa
    39361 atattaaatg agaaaaataa aaaagataat aaaagaaaga gattatttat gttattataa
    39421 gtttatgtgt tattgtaaac tataaattat ttagtaaaat taaagtaaaa attatggtat
    39481 tttgtggatg aaggtagact tttttgtaaa atattattaa cataaatata tgaggtgatt
    39541 aaatgagtga gctatcagga aaaggctgtg aaattatagt tccttttgag gaaagacttc
    39601 cagtaagaga tatagaaaaa agtataataa aaaaatatag aaaaaattta tggtccaagt
    39661 ttatgaaggc aataagagat tataaattgg ttgaagaagg ggataagata gctgtagcaa
    39721 tttctggtgg aaaagacagt attcttatgg ctaaaatgtt tcaagagtta aaaaaacatg
    39781 gacaagttaa ttttgatgtt gaatttattg ctatggatcc tggataccat gcaaatataa
    39841 gacaattact tatagataat tgtgagtatc taaatatacc aatacattta tttgattcaa
    39901 gaatatttga gatagcagat gaaatagcaa aagattatcc atgctatatg tgtgcaagaa
    39961 tgaggagagg agcattatat tcaaaagcag aagagttagg gtgcaataaa cttgcattag
    40021 gtcatcatta tgatgatgta atagagacaa caatgcttaa tttattgtgt gctggaaact
    40081 ttaaaacaat gcttcctaaa ctcaattcta ctaattttga aggtataaaa attataagac
    40141 cactttatta tataagagaa gaacatatta taagatttat tcaaaatagt gggatatggc
    40201 cattaaattg tgcatgtatg gttgctgcta aaaaaacagg caataagaga tatgagataa
    40261 aagatttaat aaagagttta gaatcaaatt ttaaaaatgt agaaaagtct atatttaagg
    40321 cagcagaaaa tgtaaatctt gactcagtac ttggttggca aaaagatggg gagaaacatt
    40381 ctttcttaga aaattttgaa taaaaataat taaaaagaat cactataaac aattagaaag
    40441 ggtgtttata ttgaaaagag tatatataga ttttgaaatg aatatgccaa attctaaatc
    40501 aaaaagagca gtatttaatt ctgatataat tgcaatcgga gcagttatgt atgatgaaaa
    40561 aacaaaaaat attgataaat ttaaatcttt aataagacca gtaagtaatg aggaattgta
    40621 tcctcatata caagaattaa cacatatatc ttctgaagaa ttgaagagtg caccaagtta
    40681 tgaagaggtc atgagaaagt ttaaaaaatg gctgggcata ttttctgata ttaaaggaat
    40741 atatactttt ggtaatttag atttgacatg tttcaataac acagatatga gaagtgctaa
    40801 aaaaaataat catccaaggt ttgtaaacaa tattagaaat ctatttgtag atataaaaga
    40861 aaaatatata aattgtggta tgagatgtat gaactatata tcattgaaaa atttacttga
    40921 atttgttaat ttagagttta gtggagatgc tcatgaccca ctaaatgatg catataattt
    40981 atttattttg gacgaggcaa ttacaaataa tatagacata caaaatcttt tgataatacg
    41041 tgatataata agagcaccat ttaatgacat aaattctaat ttagataatt gttttgataa
    41101 atttaaggaa tcactatata aaaaagaaga aaattacaat attgtagatt tttcagttga
    41161 aataataaaa actgtgagaa tgtacttatt aacaataata gatgtaaata tacaaaattt
    41221 agaagttatg aaagatataa gtaaaaaaat ggatactata gataaattga aagatataga
    41281 ggaaggctat ttttatttat tagaagatgt atattttgat atgaaagata tattagaaga
    41341 tttaatgctt tataggatgc atgaagatga gtataagcat gagatagaaa atataataaa
    41401 aatgcttgat gaagacttag ataatgaaaa aatatatata aataaatgta atgacttaaa
    41461 tgttgttaat aagatataag aaattataaa taatagagta gaacttgata attataacaa
    41521 ttttttataa aactgaaata aaattaaatt aatataaaaa taatatacaa taaaaaatgt
    41581 agagagatga ttactttcta catttttatt gtatattact ttaggtttaa aaatgtatta
    41641 tatgctttat aattaatata ttttatagat attttatctt tataaaatat aaaaactact
    41701 tattgcgaaa gtaattgatt tgttgtatta taatttacat gaattatgta agacaatcaa
    41761 aattcagtat tataagagta catatattca aatttttaac aattaattta tataattaaa
    41821 aaatgaaggg taggatgaag tcatgggttt tagagaagta aaaattgagg aactacagtt
    41881 taatccattt actaagattg gcaaagaatg gttacttata acagctggtg attcagaaaa
    41941 gtttaacaca atgactgcta gctggggtgg tgttggagta tattggggta aaaatgttgt
    42001 tacaacttac ataagaccac agagatatac aaaagaattt gtagatagta atgatacatt
    42061 tacagttgcc ttctttgatg aaacgtatag agaagcttta aatatttgtg gtactatttc
    42121 tggtagagat ataaataaaa tagaaaaagc aggacttaca ccatattttg tggatgacac
    42181 agtagctttt gaagaagcta atatgattat agtatgtaaa aagttatatc atggtaatat
    42241 gccaccagaa aactttgatg ctaaagaaaa tgataaaaaa tggtatccag agaaagacta
    42301 tcatactatg tacatttcag aaattataaa agttcttgta aaagaataat tataataaaa
    42361 agtatctaaa aagaacttat tataagtaaa tgattgtact ttcttatctt atatttaagt
    42421 agatgctaat aagtaaataa atattaattt taaataaata ctattataaa aaagatgaac
    42481 tatatttgct agagttcatc tttttattta tgtaagcact tatataagta gagatttact
    42541 tgagtaaaag tatttatttg agatatttga gtacacttta taagtatttt tatgctaact
    42601 agaaatact
//
LOCUS       DBGJFK010000029        41815 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.029, whole genome shotgun sequence.
ACCESSION   DBGJFK010000029 DBGJFK010000000
VERSION     DBGJFK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41815
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.029"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            113..709
                     /locus_tag="ACOIAP_001825"
     CDS             113..709
                     /locus_tag="ACOIAP_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGZ2638711.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYMY
                     KFESMSYIILLIALFTGIYRIILTPIYAVLLKIVYLFV"
     gene            739..1458
                     /locus_tag="ACOIAP_001826"
     CDS             739..1458
                     /locus_tag="ACOIAP_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGZ2638712.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            1460..1999
                     /gene="scpB"
                     /locus_tag="ACOIAP_001827"
     CDS             1460..1999
                     /gene="scpB"
                     /locus_tag="ACOIAP_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGZ2638713.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIVNKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVVTNE"
     gene            2157..2786
                     /locus_tag="ACOIAP_001828"
     CDS             2157..2786
                     /locus_tag="ACOIAP_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HGZ2638714.1"
                     /translation="MEFNELFNFKYLIIAVIFLISVTMLILISHINILIMADINNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSVYRLLKKI
                     KIHELYSNINFGTENIGLTSSVYVLINTLYGNLFNIIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIKSRIKDLFNIIIMINKIMNKNKGNKEGDSNESNRFNTESYGNNS"
     gene            2740..3168
                     /gene="ytfJ"
                     /locus_tag="ACOIAP_001829"
     CDS             2740..3168
                     /gene="ytfJ"
                     /locus_tag="ACOIAP_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HGZ2638715.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            3406..3846
                     /locus_tag="ACOIAP_001830"
     CDS             3406..3846
                     /locus_tag="ACOIAP_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGZ2638716.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            3862..5313
                     /locus_tag="ACOIAP_001831"
     CDS             3862..5313
                     /locus_tag="ACOIAP_001831"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HGZ2638717.1"
                     /translation="MNIKCSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEVYKSS
                     DVNVLNLNLNSDEIGSFAEGILLGNYKFDRYKTKSKNFERKEVDTITIFTEKDVECQI
                     KKAKILANSTIIARNLVNEPSNVIYPKTLAIETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIINSMANKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKVKGATGEPVRTLYYLAEI"
     gene            complement(5405..6073)
                     /locus_tag="ACOIAP_001832"
     CDS             complement(5405..6073)
                     /locus_tag="ACOIAP_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HGZ2638718.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSTNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFKVNRYALRDNLAI
                     CFIYFSFIFLLNTLTNSQYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            6342..6482
                     /locus_tag="ACOIAP_001833"
     CDS             6342..6482
                     /locus_tag="ACOIAP_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638719.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(6657..6977)
                     /locus_tag="ACOIAP_001834"
     CDS             complement(6657..6977)
                     /locus_tag="ACOIAP_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HGZ2638720.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NIDK"
     gene            complement(7097..7834)
                     /locus_tag="ACOIAP_001835"
     CDS             complement(7097..7834)
                     /locus_tag="ACOIAP_001835"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HGZ2638721.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDIITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGNYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            8048..9868
                     /gene="acd"
                     /locus_tag="ACOIAP_001836"
     CDS             8048..9868
                     /gene="acd"
                     /locus_tag="ACOIAP_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HGZ2638722.1"
                     /translation="MKKKAALATLAMLPLSVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKLNGDSLRTSTNKEKQVT
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLSKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDDSSQSNDKKNTDKFVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADASNNNSNSNSDSSSSNNGNNSSSGQVNGMS
                     GISGAKIDYKSLNYTLASHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSSF
                     VNASSSDIEYYLNPKNFINTTKGMMQFLKINSYRGGISESSLNSYLNGLSSSVFKNQG
                     ATFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFGI
                     GAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYINSSKYNQNTIYKMKWNYDY
                     TWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            10081..14379
                     /locus_tag="ACOIAP_001837"
     CDS             10081..14379
                     /locus_tag="ACOIAP_001837"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGZ2638723.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKINKERLIRINDREMEEKIRALEIGKVNSCEESEEEGYVIKSEVDEELIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRKEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHPAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEEDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSVGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFNKIPVATGDVHFLDKHEA
                     ILRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIAEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIIVGEKTLLPPMAAIQGLG
                     GNAAINIQTERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            14583..15044
                     /gene="rimP"
                     /locus_tag="ACOIAP_001838"
     CDS             14583..15044
                     /gene="rimP"
                     /locus_tag="ACOIAP_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000028 - ribosomal small subunit assembly
                     [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGZ2638724.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIVNGKEIEFNRKDVAIVRLAIKF"
     gene            15074..16228
                     /gene="nusA"
                     /locus_tag="ACOIAP_001839"
     CDS             15074..16228
                     /gene="nusA"
                     /locus_tag="ACOIAP_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGZ2638725.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKKIEAEDVEAEFIEQEELDTSDDNFSDEE"
     gene            16235..16516
                     /locus_tag="ACOIAP_001840"
     CDS             16235..16516
                     /locus_tag="ACOIAP_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGZ2638726.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            16506..16817
                     /locus_tag="ACOIAP_001841"
     CDS             16506..16817
                     /locus_tag="ACOIAP_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L7Ae/L30e/S12e/Gadd45 family ribosomal protein"
                     /protein_id="HGZ2638727.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            16839..18779
                     /gene="infB"
                     /locus_tag="ACOIAP_001842"
     CDS             16839..18779
                     /gene="infB"
                     /locus_tag="ACOIAP_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGZ2638728.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGDELE
                     LALEMLGEDLSQENGNIIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            18822..19202
                     /gene="rbfA"
                     /locus_tag="ACOIAP_001843"
     CDS             18822..19202
                     /gene="rbfA"
                     /locus_tag="ACOIAP_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGZ2638729.1"
                     /translation="MASYNRTRRISEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKIDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            19183..20166
                     /locus_tag="ACOIAP_001844"
     CDS             19183..20166
                     /locus_tag="ACOIAP_001844"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGZ2638730.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLGFLVEGVKIYKSNEFNMKNYSIIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNAHASSFEMAKNLLVLGAQKNTIIQNIYQSNSYDYYKLLGEA
                     LKALEIFNSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYIDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            20179..21084
                     /gene="truB"
                     /locus_tag="ACOIAP_001845"
     CDS             20179..21084
                     /gene="truB"
                     /locus_tag="ACOIAP_001845"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGZ2638731.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEEIKRA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKNIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNSNAIKYYSNGGSIDDKRFLKNNFNKDDEFVRVYST
                     DNFLGLGKLSKHNNIISVKSDKMFI"
     gene            21214..22143
                     /locus_tag="ACOIAP_001846"
     CDS             21214..22143
                     /locus_tag="ACOIAP_001846"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGZ2638732.1"
                     /translation="MEIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMASVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            22247..22504
                     /gene="rpsO"
                     /locus_tag="ACOIAP_001847"
     CDS             22247..22504
                     /gene="rpsO"
                     /locus_tag="ACOIAP_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGZ2638733.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            22744..23589
                     /locus_tag="ACOIAP_001848"
     CDS             22744..23589
                     /locus_tag="ACOIAP_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGZ2638734.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFIAEGYHIICMTGAANASGTFQSAMIA
                     KNDVDENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEKIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIITIGCGDNLHDCEILKDEVNKRIKARSVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            23714..25825
                     /gene="pnp"
                     /locus_tag="ACOIAP_001849"
     CDS             23714..25825
                     /gene="pnp"
                     /locus_tag="ACOIAP_001849"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGZ2638735.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCIGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            25948..26691
                     /locus_tag="ACOIAP_001850"
     CDS             25948..26691
                     /locus_tag="ACOIAP_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2638736.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDESGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            26849..28096
                     /locus_tag="ACOIAP_001851"
     CDS             26849..28096
                     /locus_tag="ACOIAP_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGZ2638737.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQLNAFTSKECTCYYVKLIDEHIDIGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLVKKEIENIRENYLTEEEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVDINSVKKVVDK
                     VFNVENIGTCIVGRDVEKILHLN"
     gene            28131..28376
                     /locus_tag="ACOIAP_001852"
     CDS             28131..28376
                     /locus_tag="ACOIAP_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HGZ2638738.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            28386..29609
                     /gene="dapG"
                     /locus_tag="ACOIAP_001853"
     CDS             28386..29609
                     /gene="dapG"
                     /locus_tag="ACOIAP_001853"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGZ2638739.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKIKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKFITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            29723..30457
                     /locus_tag="ACOIAP_001854"
     CDS             29723..30457
                     /locus_tag="ACOIAP_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HGZ2638740.1"
                     /translation="MKDYREDNERFDKDNCSEESSSEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            30580..32988
                     /locus_tag="ACOIAP_001855"
     CDS             30580..32988
                     /locus_tag="ACOIAP_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGZ2638741.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIVGGWLISIF
                     ALILSVMFIFNISIKDMISNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGRNTDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQ
                     SMPELDVLKELQKATNENPVIDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSNY
                     KKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQ
                     PSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLES
                     EEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYKA
                     NPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFADA
                     QVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVA
                     TQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAK
                     PVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEAI
                     EFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQN
                     LEGE"
     gene            32991..34049
                     /gene="mnmH"
                     /locus_tag="ACOIAP_001856"
     CDS             32991..34049
                     /gene="mnmH"
                     /locus_tag="ACOIAP_001856"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HGZ2638742.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTIPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNLLVLKECINKF
                     RKRLGHKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYNKVINFNDTEEA
                     LEDVIDLYESILEGENEC"
     gene            34043..35377
                     /gene="rimO"
                     /locus_tag="ACOIAP_001857"
     CDS             34043..35377
                     /gene="rimO"
                     /locus_tag="ACOIAP_001857"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HGZ2638743.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILRELSEMHQIVSLNDIEFVFNEDLPRYLSTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEDVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEIGEFVSVKINDAMEYDLMGDVLYELA"
     gene            35364..35906
                     /gene="pgsA"
                     /locus_tag="ACOIAP_001858"
     CDS             35364..35906
                     /gene="pgsA"
                     /locus_tag="ACOIAP_001858"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGZ2638744.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVLLLLGAQFANGLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            36173..37219
                     /gene="recA"
                     /locus_tag="ACOIAP_001859"
     CDS             36173..37219
                     /gene="recA"
                     /locus_tag="ACOIAP_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGZ2638745.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEIDEKVRAFYNLNEEH
                     EEAGNSVSKEIVEE"
     gene            37395..38936
                     /gene="rny"
                     /locus_tag="ACOIAP_001860"
     CDS             37395..38936
                     /gene="rny"
                     /locus_tag="ACOIAP_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGZ2638746.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            39246..41582
                     /locus_tag="ACOIAP_001861"
     CDS             39246..41582
                     /locus_tag="ACOIAP_001861"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2638747.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYLYDSVFLVSTKTNNYYHFDGLNRNLSVNNSENQWYYTFLNKEDEYSLNVDNDEA
                     SDNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYDDKFDVVTHLIDDKGFVQ
                     LAVDKTGHEHINFFENSSSDLSNSKKLILNNEKEQKSFWYSSEKSKRYIVCQYIPSLK
                     WYLVLENDFTLMSKQLYMQFLKDIGVIVLIIIFVLFTITHVLKKYKKQIVKLSVSQKL
                     EYQKLLSQSTEGLYENIFEIDITNNRAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKCYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDEEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDDFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     SNNYVLIDKLERFCSKINQKKFAEQAGFSIGCSIGVSMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHVFSEDSTDSISFHIDPRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSTDFNIFSPVLQDDLQMVLDTLKEAISKRETFEVVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISNINTLLENK"
BASE COUNT        16990 a         4332 c         7751 g        12742 t
ORIGIN      
        1 ttttaatttt atgcctagaa gttaaaatta ttataatata aaataatttt gattataagt
       61 tatttaattg ttataataat attaaaaaat ttgatttagg agatgtaaat taatgttaag
      121 tatgaatata ggagaaatag tagcaagttt agttggtata gctatggcga tatcaataca
      181 tgagtttggt catgcttatt cagctcactt attgggagat gatacagcta aagcttatgg
      241 tagaatgaca ttaaatcctg taagacatgt tgacccaata ggtcttttgg ctatgtttat
      301 tcttaaaata ggatgggcaa aaccagtacc agtaaatcca aataacttta aaaattataa
      361 gataggaaac ctgatagttt cacttgcagg agttttttgt aatgttttga ctgccatact
      421 ttgtgtaatt atcaataaat atgtgcatat gtatgcgata aatacaatag ctgaatatgt
      481 gtttttatat agtattggat ttgcagcttt taatttgctt ccaataccac cacttgatgg
      541 atggggagtt atatctacat ttgtaccgta taaatggaat gaatatatgt acaaatttga
      601 aagtatgagt tatataattt tattaattgc tttatttact ggtatatata gaataatatt
      661 aactccaata tatgctgtac tactaaaaat agtatattta tttgtttaat ataataaaca
      721 gattaaagag ggattgatat gaagtataat atacaattac aggtctatga agggccatta
      781 gatttactgt atgatttaat aacaaagcat aaaatagaca taaaggatat atctataata
      841 gatataacta agcagtatct aaattatttg aaaatgctag ataaaatgga tttagagata
      901 actagtgagt ttataactat ggcatcaaaa cttttagaaa taaagtctaa atatctactt
      961 tataagcaaa aagatgaaga agaagaccca agaatagaac ttatggaaaa gctagaagaa
     1021 tatagaaagt ttaaggtagc atcacaagat ataaaagaaa atataactta tgttaatgag
     1081 agattttata gaaataaaga agagataatt attgatgaca atgtagattt agaagatata
     1141 tcaatagaag caataaaaaa tatactccca tacatattta aagttaaaac atcacagata
     1201 gaaaatgcta atgatgagaa actagacaaa atagtaagga agaagataat atctgtagaa
     1261 gaaaagatat tgtatataag agatattata aaagataaga ttgaagttac ttttacaaat
     1321 attataaaat catatgaaaa tgatgaaata atagctactt ttttatctat attagagctt
     1381 ataaaagaaa aagaaatagt tgtagtacaa gatatatttt ttgatgatat tctaataaga
     1441 aaaagttcgg agtgttaaaa tgaaaagaga agatataaag tatattatag aatctgttat
     1501 gtttgcatat ggagagccga taagtataaa agaattaaac tatatagtaa ataaagaact
     1561 ttcatcaaaa gaaatagaga ttatgttaaa tttacttatt gaggagtaca gagaacaaaa
     1621 tagaggtatt caaataatca agttagagaa taagtaccaa atgtgtacaa acaaagacta
     1681 tgcagaatat ataaagaaga ttattgaacc aaagaaaaag aaaagtttga gccaagctac
     1741 attagaaact ctaactataa ttgcctacaa acaaccaata acaaaggtag aaatagagga
     1801 tataagagga gtaaaatgtg ataaggtatt acaaactttg tttgaaaatg aacttataag
     1861 agaagctggt agactgaata agatagggaa accaataatt tataaaacaa cagatgaatt
     1921 tttaaagttg ttgaatatag aaagtcttga agagttgcct cctatagaaa attatcaaga
     1981 agtggtaaca aatgaataaa aatataaaaa cacaacaact tagagaattt ttaactttga
     2041 aagatttaaa attctctaag ttgttgtgtt ttttgtataa atataaaatg ataattctct
     2101 taaaataaat atggataatt aagtataaat agtaattttt tgatgataat ataaatatgg
     2161 agtttaacga attatttaat tttaagtatt taataatagc tgtaattttt cttataagtg
     2221 taactatgtt gattttaata tctcatataa acatcttaat aatggctgat ataaacaaca
     2281 aagatatttg cttaaagctt aatataaaat acatgtttaa tttaataaat ataaatagac
     2341 aactttatcc agctgaaaat agtaaaaata atgataaaaa agaggggatg aagaataata
     2401 tagattcaag tatattatta gctgatgacc ttttgagcgt ttatagatta ttaaaaaaga
     2461 taaaaataca tgaactttat tcaaatatta attttggaac tgaaaatatt ggcttaacat
     2521 cttctgtata tgtattgata aatactttgt atggaaattt atttaatata attgatgcag
     2581 aaaaaatgta tttaaatgta aatccagatt ttacaaaaga ttatgttttg ggaaatataa
     2641 ggatacatat aaaatcaaga ataaaagatt tatttaatat tataataatg attaataaaa
     2701 ttatgaataa gaataaagga aataaggaag gtgatagtaa tgagagcaac aggttcaata
     2761 cagagtctta tggaaacaac tcttgaaaca attaaaggtt ctatagatgc aaatactatt
     2821 ataggagacc ctataaaaac agatactaca gtggttgtac ctatatcaaa ggttacaatt
     2881 ggttttggta taggaggagg agaatattca aaaggatatg atgataaaga tagggaaatt
     2941 gaattaaaaa atgaaaaatc agatacgaat tttgctggag gtagtgcagg ggctatatct
     3001 gtacaaccag tagcgtttgt agtagttgaa agtggagaaa ctagaataat gagtttagat
     3061 agcaatatca atctagtgga taatatatta tctataactc ctagagtatt ggagaaaatt
     3121 caaaatatat cacaaagtaa taagaatcaa gataaaaaca atatgtaaga ataaaatatg
     3181 tatatggttt taaataaagt agtggggtta gtataaatcc cactattttg ctgtgtactt
     3241 taaacattta tatctaataa gattttagtt taaaacaatt taaatagata ataaagttga
     3301 tatatagtat aattataaaa agaaaagaag tattatatta tagatatata aacacatttg
     3361 agatataaga gggagttata aatcattagt tttgaggtga atgttatgag cgataaagaa
     3421 ttatctattt tgttgttaga aagtatgaat aattttcata atttaataaa gattattaat
     3481 aacgaaagat ataaaaaaga taaggttctt acagaaagac agttctttgc cttagtaaaa
     3541 ataagaaaac atgataaaat agagcttaaa aacctaagta gagatttaca tgtatctact
     3601 tctagtttgt gtatactact taataaattg gttgagcaag agtatgtata tagagaagaa
     3661 gatagtagag atagacgaaa tactttttat ggaataacta aaaatggaga aaagatattg
     3721 gataatgaaa tactaaagtt tgtgtctata ataagtgata aaatggattg cttagatata
     3781 gataataaag ataaattatt tacttctttg gaagaatcta aaaatataat agaacaacta
     3841 ttttaaaaag gagaatttat tatgaatata aagtgttcta aagaaatatt aaaaagttta
     3901 gaaaatgcta taacagtagt agctctattt gagggagaag atgtttctac gacatttgat
     3961 aaaataaata tgataagcag aaattttaat tctaaagaaa atagtataga tactgtaaca
     4021 ttggttgaaa ataacaattt ggtaaatgtt tgtcttgttg gttttggtaa gagagagtta
     4081 ttgaatagag aaaaaattag aatcataggt gggaatttgt gtaaaaaatt aaaaaatata
     4141 ttgaaaaatg aagtatataa gagtagtgat gttaatgtac tgaatcttaa tttaaatagt
     4201 gatgaaatag gttcttttgc agaagggata ttacttggaa attataagtt tgataggtat
     4261 aagacaaaaa gtaagaattt tgaaagaaaa gaagttgaca ctataactat atttactgaa
     4321 aaagacgttg agtgtcaaat aaaaaaggct aaaatattag ctaattcaac tataatagct
     4381 agaaatctag ttaatgaacc atcaaacgta atatacccaa aaacattagc aatagaaaca
     4441 gtcaaacttg gtgcagagtt tggatttaat gttgatgttt atgaagaaga aaaaataaag
     4501 gcattgggaa tggatgcttt tttcgctgtt tcaagaggtt caattaataa accaagattc
     4561 atagtaatga gatactttgg agacaaagaa agtacggata tattaggtct agtaggtaaa
     4621 ggattgactt atgatactgg tggatattct ttaaaatcaa atgcttctat gctagatatg
     4681 aaaaccgata tggctggtgc cgcgagtgtt ataggtgcta tgtgtgctat atctcaaagt
     4741 aaattaaaga aaaatgttat agcagtagtg gctgcatgtg agaatgcttt atcaggaggt
     4801 tcatacaaac ctggagatat aattaattct atggcaaata aaactattga agttttaaat
     4861 acagatgctg aaggtagact tacattagct gatgcaatat actacattat aaacaatgaa
     4921 aaagtgacaa aggtggttga tgtagccaca ttaactggtg ctgccttaac attgttaggc
     4981 aatgttgcaa ctcctatagt aacaaataat gatgattttt attgtgaatt agaaaaagcc
     5041 gccactttat caggagaaag agtatggaag atgccaattt atgatgaatt taaagatatg
     5101 ataaaaggag aagaagcaga ccttaaaaac actggtggta aaaatgctgg atgtataact
     5161 gcaggagctt ttattggtga atttgttggg aatactcctt ggatacatat ggatatagca
     5221 gggacaagta catcatcaaa atcaattgga tacaaagtaa agggggctac aggagaacct
     5281 gtgagaacat tgtactattt ggcagaaatc taaaacaaca attatagaat ataatttata
     5341 aagccacgtg gatatttttg taatttaagg ttatctatgt ggctttattt tttatttaag
     5401 taaattattt actctttttc tttttttcaa gtataaaagt atctctatta aataaaagag
     5461 caggtatgta cataatacta gtaacaaaaa taaatgtaaa aatagcagtt gtactatggc
     5521 ttaaaaaacc ataatagtat tgtgaattgg taagtgtgtt tagtaaaaat atgaatgaaa
     5581 aataaataaa acatatagct aagttatctc taagtgcata tctgttaact ttaaattttc
     5641 taacatcaac catatatata tctgcataaa ttattaagca cttagagaag ataaatataa
     5701 aatatattaa gctaggaaat tcataaccca agtttgtaga aaaaataagt tctccaactg
     5761 aacaaactaa actccaagaa aaaaatatat taaaaagatg atactgctta aaaatcagta
     5821 tagctataca cagatatatg caaatataat tgattccaat tggtaaagaa tttagggtac
     5881 tataattacc tgaagaaata agtaataatt gctctagagc cataattatt acaagcaatg
     5941 tacaaattat cttctcgact gtatagctat aaggtaaaat atttttggtt aattttggac
     6001 aatagtataa aaataatcca aatataaaga gacttacaaa ttgttcacta gaaaaaagaa
     6061 aaattttaaa catataacat tctctcctat aataaattta atatgtatct atataaatat
     6121 attcattata tctcaattta atatgtaaaa aatataataa tagttagatt ttttatatca
     6181 attttaatat gtaaaatatc ctattgtttt gtagatatat cctaattatg tcaaaaaata
     6241 aaaaagtttt tatttattag agtttttgga aataataata acagatatta taattaatta
     6301 acagtttttg taagtatttg acaatagaga gggtgtaaca aatgggaata atagagtcag
     6361 catcaaaatt ggctgagatg gttcatttat tggctgttga aaaagggata actgatatag
     6421 aagcatggga tgaagctgtg aaagaataca gcaaaattta cgaagaaaga agaaatgaat
     6481 agaatgataa aaagtgacaa cttgatgata aaaaataact ctatttaaat aaattcaatt
     6541 tttatagaaa cattaaaaat aatataaata aaaagatggt atttcaaatg taagtaaaaa
     6601 atcattttgg gataccatcc ttattattta ttttaataat atataagtaa taaattttac
     6661 ttatcaatat tttttatgta acctcttttt tctagctttt ttatatgctc tttgcgtatt
     6721 tcatcaagat taataccata ctgttcttct agcttaaaca tcatagtaac acatgtctga
     6781 gctacatcca ttagttcctt agcagttttc tttataatat caacttcatc taagtcatta
     6841 ttttctccac ttagatttct aaatttacct atacattcag ctaattcacc ttgttcttca
     6901 cccattttga taaatgtaga ttctagggtt gggtctaaat tattaagctc tggtaaagat
     6961 atagttttta gtttcataaa agctcctttc aagttattca tatttatact aaaacatcat
     7021 aacaaaaata atactaaaaa aaaactttaa attcaacata aaaacttaca tatataataa
     7081 aaatcgtgaa ataaatctat atttgtctta atacagcttc atataaaact tctccaatag
     7141 gtttatttat tacaagagaa gctgacttat catagactgt atttgcttta ttaataagag
     7201 caatataatt acctttgtaa taatctataa aacttgctgc tggatataca gccaatgatg
     7261 tacctcctat aattagtaaa tcagcattac ttatagcaga aattgtttta gtaatgatat
     7321 cactatcaag agcttcctca taaagtacta catctggttt tactatagaa ccacagttat
     7381 cacagtaagg aatattacca ccaagattta acatagattc taagtcaaaa aacttaccac
     7441 atttagtgca ataatttcta tgtacagagc catgaagctc taggacattt ttacttccag
     7501 ccatttgatg aagtccatca atattttgag ttataacagc tttaagttta cccatttctt
     7561 cgagttttgc taaagctatg tgagcattgt tgggttttgc attagggtat attaatttgt
     7621 ccttataaaa ttcaaaaaat tcttctgggt atctaacaaa aaaagtatgt gaaactaatt
     7681 gttcagcagt aaattgtttg ttgagttttt ggctaaataa tccagtagag cttctaaagt
     7741 ctggaatatt agattcagtt gaaacacctg ctccaccaaa aaatacaata ttattgtgat
     7801 tagctattaa gtcttttaag ctatttgcat ccatagttac acctccaaat tattatatat
     7861 aaattgtact acatattaag gtatttatgt tttattattt caaataaata catagtttaa
     7921 taagttaaat aaagggaata taaataaaat gtatacataa tataaatagg caatatttac
     7981 taaaataaca agttgtcgta taattatatt aaaattgttt tagtgtataa gaagggcggg
     8041 gaagtacatg aagaaaaaag cagctttagc aacattagct atgttaccct taagtgtggt
     8101 aaatgcacat gctgatggag atataggcat agtgactata aattatttaa acgtaagaaa
     8161 tgaaccaact gctgaaagta gtatagcctt tgttgctaaa aaagatgata aagttttgat
     8221 taaagactct tctaatggat ggtataaaat aaaagctgaa tctggacaag aaggttgggc
     8281 ttcatcaaaa tatatagcaa aattaaatgg tgactcttta agaacatcta caaataaaga
     8341 aaaacaagtt acttcaaata gtttaaatat gagaaatgga gcaggtacaa gttatagagt
     8401 aataactgta ctaaaaaaag gtcaaaaagt agaagtaata tcagagagta atgggtggtc
     8461 taaaatcaaa tatgatggaa gattagggta tgtatctagt tcttatttag gagatgtttc
     8521 aaattcaact aataaatcaa aaacaaaaca agtgaataca acttcactaa atgtgagaag
     8581 tggaccaaat acaagttatg gcttgttagg taagttgtca aaaggaagta aagtagaagt
     8641 aatatcagaa agtaatggat ggtccaaaat aaagtataat ggaaaagatg catatgtatc
     8701 tagtatgtac ttatcagatg taagtcaaag taattcagac gattctagtc aaagcaatga
     8761 taaaaaaaat actgataagt ttgtaaatac agcttcttta aacgtaagaa gtggaccagg
     8821 ttctacatat agcaagttgg gaaaggttta taaaggaagt aaggtaactg tgctatcaga
     8881 aagtagtgga tgggctaaga ttaattttaa taataaagaa gcctttgtag taggtaatta
     8941 tttatctact tcagcagatg catcaaataa taactcaaat agtaactctg atagcagttc
     9001 tagtaataat ggtaataatt catcatcagg tcaagtaaat ggtatgtcag gtataagtgg
     9061 agctaaaatt gattataaat ctttgaatta tactttggca tctcatataa gtaaacaagt
     9121 tgagaaagca gcatcaggag gaaatgtgat agcaccaagt aataggaaaa gcaccccaag
     9181 tcctgaattt agtacttttt cagcccaaag aacaagctca tttgtaaatg caagttcaag
     9241 tgatatagaa tattatttaa atcctaaaaa ttttataaat actactaaag gtatgatgca
     9301 gtttttaaag attaacagtt atagaggtgg tatttcagaa tcaagtctta actcgtatct
     9361 taatggttta tcttctagtg tatttaaaaa ccagggagca acatttataa atgctgcaaa
     9421 gaagtataat atagatgttg tatatctagt atctcatgct atgtgggaaa ctgcttatgg
     9481 taagtctaca cttgctcaag gtcagacatt aacatcttat aagggtcaac ctcttagtaa
     9541 accagttaaa gtatacaatt tttttgggat aggagcgata gataaaagtg ctaatgtttc
     9601 aggtgcagag gcagcgtatt ccaatggttg gactagtgta gaagctacaa tagatggatc
     9661 tgcaaagtgg atatcacaaa attacataaa cagttctaag tacaatcaga atactatcta
     9721 caagatgaag tggaattatg attatacatg gcatcaatat gcaactgatg taaactgggc
     9781 taatgggatt tctggaatta tggagaattt aattggtctt tatggaggag gaagtagttt
     9841 ggtttttgaa gttcctcaat ataagtaata tatgaataaa aaatatagac tatgggtagt
     9901 tttcatttta tttaaattat ctatagtctt tttgtatata atttacatgc tgtaaattta
     9961 atgttaacaa aatttttatg ctataatatt aattctaagc aaatataagt gagtaataga
    10021 tagaaataga taaaaagtgg taataatata tatagataat tttgagaaag gaggatatag
    10081 atggaaagta ttaaggaata tttggataag ttagaaatta ataatagtgg tcttggaaag
    10141 caacttaaag aagtttacat aaatagagta gtttatttta aggaagataa gatagtttat
    10201 ttttatctga cttctaagga tattgtttct catgagcttt tagataaatt taaagaagaa
    10261 ttgatgtata aactcgatta ttttaaagat atgaggatga agataagatt tactggtctt
    10321 gaaagaaaat ccaataaaga tgttataaaa aaatattgga ataatatatt gtatatatta
    10381 aagtatcttt gtccatctat tgcaggatgg tataaacagg tagaatttct ttgtttagag
    10441 gaagaattaa aaataaaact tccaaaaggc atattttatg agcgattaat gaaaaaaaat
    10501 gtaacctatg tacttaaaac cgtgcttagt gaagaactgg gattagattt aaatataaca
    10561 atagaaaaag cggttgatga aaagataaat aaagagagac tcataagaat caatgataga
    10621 gaaatggaag aaaaaattag agctttagaa attggaaaag ttaatagctg tgaagaaagt
    10681 gaagaggaag gttacgtcat taagtctgaa gtagatgaag aattaatcta tggagataat
    10741 gcaaatgcta tgattgaaaa tatagttgaa ttaaatgcat cttctggaac tgttgcagtt
    10801 gttggagata tatttgatgt tgatactaaa gagcttaaaa atggaaaaat acttatgata
    10861 gcatcaatta cagattatac tagttcaata agttgtaaac tttttttaac agatacaaat
    10921 aaagatggag tacttgaaaa tgttaaaaaa ggagcatact taaaaatcaa gggtgacata
    10981 gtttatgata catatcaaag agaaattagt atgatgatta gtggtataag aaaagaaact
    11041 agaaaagaga gagaagataa atcagaggaa aaaagggtag aactacatgc acatactcaa
    11101 atgtcttcta tggatgctat ttgttctgtt aaaaagcttg tagaacgtgc ggctaaatgg
    11161 ggacatcctg ctattgctat aacagaccat ggagttgtac aaggatttcc agatgccatg
    11221 aatgcaggta agtcaaataa tataaaaata ctttatggag tagaagggta cttggttgaa
    11281 gaggattctc ttattataga ggatgcaaat gataaagaac tttctcagac atttgttgta
    11341 tttgacatag agacaactgg tttttctaat acaaatgata aaataactga aattggtgct
    11401 gtaaaaatag aaaactttaa aattgtagat agatttagtg aattaataaa ccctgaaaaa
    11461 gatatttctt ataagataca ggaattgacg ggaataacta atgagctaat taaagataag
    11521 ccgaccattg aagaagttct tcctaagttt atggaatttg ttggagatag tgtattagta
    11581 gcacataatg cggaatttga tactggattt atatcgcaaa aatgtaggga acaaggtttg
    11641 ttatataata acaaaaaagt agatacactt atgctagcaa gagtaatgtt accaaactta
    11701 aaaagacata gactaaatgt cgttgcaaaa gaacttggta ttcctctttt aaatcaccat
    11761 agagcagtgg atgatgctga ggctacagca cttatattta ataaattttt gcagatgctt
    11821 acggaaaaag gtgcaaaaac attaagtgat gtaaacaata tacttggaaa gattgattat
    11881 acaaaactta gcacaaatca tataaccttg atagcaaaaa attctgtagg tataaaaaat
    11941 ttatataaaa taatttcaga tgcacatgta aatcattttt ttagagcacc aagaatcctt
    12001 agaagtgtgt taaatgaata taaagaagga ttaataattg gttcggcctg tgaagctgga
    12061 gtggtttttc aagctgtaaa gaaaaatgta tctgatgagg aaatgaaaaa aataatagat
    12121 ttatacgatt atattgaagt aatgcctata gataataata ggtttatgat tgataaagga
    12181 gaagtaaagg acgaagaaga gttaagggaa ttgaatagga aattaattga tacagctaaa
    12241 aaatttaata aaattccagt agctactggg gatgttcatt ttttagataa acatgaagct
    12301 atcttaagaa aagttcttaa atattctcaa ggttttaaag tagatgaaga agaaacttat
    12361 ttacatttta gaacaacaga tgaaatgttg gaagagttta gttatcttgg agaagaattg
    12421 gcatatgaag ttgtagttga aaatagtaat ctgattgccg atatggttga agatataaaa
    12481 cctataccag atgatactta tcctccaatt atagagggtt cagatgtgga gttaagagaa
    12541 atgtgttaca aaaaagcaaa acgaatctat ggagacccaa taccagaaat agttcaaaaa
    12601 agactggata gagaattaaa ttcaataata agcaatgggt atgcagttat gtatattata
    12661 gctcaaaagc tagttgcaaa atctctttca gatgggtatt tagtaggttc aagaggttca
    12721 gttggttcat cttttgcagc tactatgagt gatataacag aagttaatcc tcttccagca
    12781 cattatattt gtgaaaatga agactgtaaa tattcattct tttatgaaat aggtgaatgg
    12841 ggttcaggtg ttgatttacc agacaaagac tgtccaaagt gtggaagaaa acttgccaaa
    12901 aacggtcatg atattccatt tgaggttttc ttaggttttg aaggtgataa ggaaccagat
    12961 atagacttaa atttctcagg aaattatcag ccaacgattc acaaatacac agaagaacta
    13021 tttggagagg gctatgtata tagggctgga acaataggta ctgtagcaga aaaaacagct
    13081 tttggatatg caagaaaata tgtggaggaa aataatataa gtgtaccaaa tgcagaagta
    13141 cttaggcttt caaatggatg tactggagta aaaagaacct caggacagca tccaggtgga
    13201 gttatggtta taccagatta taaagatgtg tatgatttta cacctataca gtatccagca
    13261 aacgatactt cttgtggtgt tataactact cactttgatt atcattcaat aagtggtaga
    13321 atacttaaac ttgatatact tggacacgat ggtcctacca ttataaggat gcttgaggat
    13381 atgactggaa taaatataac agaaattccg ttggatgata aagagactat gtctctattt
    13441 acatctacag aagcattggg tgttacacca gaagaaataa actgtcctat aggttgcctt
    13501 gctgtaccag agtttggaac taagtttgta cgacaaatgt tacttgacac caaacctact
    13561 acatttgcag aacttgtacg tatatctggt ctttctcatg ggacagatgt ttgggtaaat
    13621 aatgcacaag acttagttag agaagatata gttggcttaa aagatgttat atctacacga
    13681 gatgacataa tgaactattt aatatttaaa ggattacctc ccaaaatgag ttttacaata
    13741 atggagagcg taagaaaagg taaaggtcta aaaccagaac acattgcgga gatgaaaaaa
    13801 aataatgttc cagaatggta tataggctca tgtaaaaaga ttaagtatat gttcccaaaa
    13861 gcacatgctg ttgcttatgt tatgacatca tttagaattg catattgtaa agttcactat
    13921 ccagaggcat tttatgcgac ttattttact acaaaagttg aggattttga tgcagattta
    13981 attgttaaag gattagatgc tataaaatca aaaataaatg aaattgagtc gctgggaaat
    14041 gatgcaacca caaaagaaaa aggtatgttg actgttttag aagttgctct tgaaatgtat
    14101 gctagaggaa taaaattatt accagttgat atatataaat cagatgcgac tgagtttata
    14161 attgtaggag aaaaaacatt acttccacca atggcagcaa tacaaggtct gggaggaaat
    14221 gcggctataa acatccaaac tgaaagaaaa aatggtgaat ttatatcaaa agaagattta
    14281 agaaagagaa caaaaatatc aaaaacggta atagaaactc ttactaatca tggttcactt
    14341 gagaatatga gtgagagaaa tcaattgtca ttgttttaag ttagcccaaa aagttgcaaa
    14401 taaaagaatt ttatgatatc atagtataga aaatagtata ctttgcagaa actaagagtg
    14461 agaccgctgt tctcactctt ttattttaaa tatattatta aaaagctggt ttaattttat
    14521 taaatatatt ttgtttaaga ttatataaac tggtcattta caattgaata ggaggaattt
    14581 taatgaaaaa aaatttagaa gctacaatcg aggagattgt aactaaaata acagatgagc
    14641 atggatttga aatggttgat gttgaatatg taaaagaagc aggagaatac tacttaagag
    14701 tatacataga taaagaagaa ggaatatctt taaatgaatg tgaattagtt agtagagaat
    14761 taagtccaat actagatgaa aaagacccta taaaagagaa ttacttttta gaggtatctt
    14821 ctccagggct tgatagagca ttaaaaaaag acagagattt tgttagatat caaggtagag
    14881 atgttgattt aaaattatat aaaccattaa atggatgtaa acaatttgaa ggtgaacttg
    14941 taggattaac agaagataat aatataaaaa tcattgtaaa tggtaaggaa attgaattta
    15001 atagaaaaga tgttgctatt gtcagattag caataaagtt ttagtggtat attaaatagg
    15061 gaggatataa aaaatgaatc atgaatttat ggaagcatta gatgaattag tagttgacag
    15121 aggtatagat aaagaaatac ttatagatac tatagaacaa gctcttttaa ctgcatacaa
    15181 gaaaaacttt ggttcagcac aaaatgttag agttgaattt gatagagaca agggagatat
    15241 aaaagtattt tctcaaagag tagttgttga tgaatcagat ttatatgata ctttcttaga
    15301 aatagagtta gcagatgcta gagagataaa tcctaattat gagttaggtg atattataga
    15361 acatgaagtt acacctaaaa actttggaag aattgcagct caaacagcaa agcaagtagt
    15421 tgttcaaaga ataagagaag ctgagagaga aatagtgtat aatgagttta tagaaaaaga
    15481 aaatgaaata gttacaggag aggttgctag agcaaataaa aatgttgttt atgtaaacct
    15541 tgggagaata gaaggtataa tgactcaaag tgagcaaata ccatttgaaa attataaagc
    15601 aggtcaaaaa ataaaattct atatacttga agttaaaaaa actaacaaag gacctcaaat
    15661 agttgtatca agaagtcatc caggtttagt gaagagattg tttgaagaag aagttcctga
    15721 aatatatgaa ggaatagttc aaataaaatc tgtagcaagg gaagctgggt caagaactaa
    15781 aatggcagta agatctatag atgaaaaaat agacccaatt ggagcttgtg ttggaccaaa
    15841 aggacttaga gtaaaaaata tagtggatga acttggcgat gagaaaatag atataataaa
    15901 atatagtgaa gacccagcag agtttatatc agcagcactt agcccatcaa aagttgttag
    15961 agtagatata gatgaagatg aaaagtctgc cttagtaatc gttccagatt atcagttatc
    16021 gcttgcaata ggtaaagaag gtcaaaatgc aagactagca gcaaaattga ctaactggaa
    16081 aatagatatt aagagcgaat ctcaagcaga acaagaaatg ttaaatcttg aaaattccaa
    16141 aaaaatagaa gctgaggatg ttgaagctga atttatcgaa caagaagagt tagatacttc
    16201 agatgataat tttagtgatg aagagtaagg agggatgatt ttgaaaaaag taaaaaaagt
    16261 gcctcaaaga aaatgcatag catgtcaaga tagagactct aaaaaagagc ttataagaat
    16321 agttaaaaat aaagaaggaa aaatattttt agacccaaca ggaagagcca atggaagagg
    16381 agcatatgta tgtaaaagct ctgaatgtct aaaaaaagct ataaagagta aagcattaaa
    16441 caaagctttt aagatagatg ttcctgatga agtctatgat aatctactta tggagttaga
    16501 agaatatgaa aaataataaa gaaaaagtac tttcgttctt agggctcgca actcgtgcag
    16561 ggaaaatagt gtctggtgat gattcaactt tgctcgacct taaaaaagga aaagtaaatt
    16621 tgattttaat agcagaagat gcatcaaata atactaaaaa actttttaaa gataaatcaa
    16681 cttttagaaa tattccatat ctattttttt caacaaaaga ggaaatagga tttgcaatag
    16741 gaaaatctcc aagagcagtt gtaggaataa aagatgaaaa tttttctaaa aagataattg
    16801 aactaataga aatttaaaat aaaatagggg gtgatcttgt gtcaaaaaca agagtatacc
    16861 aaatagcaga agaattaaat atatcaaatg aagagcttat aaataagtta gctgaattag
    16921 atataaatgt aactgacaaa gattcagtat tagaaggtga tgagttagaa ttagcacttg
    16981 aaatgttagg tgaagattta tctcaagaaa atggaaatat tatagaaata gatggaaagt
    17041 tgacagtaca agtattagca acaaaattag ataaatctcc atcagaaata attatgaagc
    17101 ttatgaaaat gggaactatg gcaacaataa atcaagagat aagttttgag attgctgctt
    17161 tggctgccaa agactatgga tttgaattaa cagtagctga aagtgatgat acagaagctt
    17221 tagaaataga agctttaatg gaaattgaag aagataaaga agaggattta aaacctagac
    17281 caccagttgt tacagttatg ggacatgttg accatggtaa gacatcttta ctagatgcaa
    17341 taagaaaaac tgatgtaatc tcaggtgaag ctggtggaat aactcagcat ataggtgctt
    17401 cagaggttaa aatcaatgga cacaaaatag tatttttaga tacgccagga catgaggctt
    17461 tcacatcaat gagagcaaga ggagcacaag ttacagatat agcaatatta gtagttgcag
    17521 cggatgatgg tataatgcct caaacagttg aagctataaa ccatgctaag gcagcaggtg
    17581 tacctttaat agttgctatc aataaaatag ataaaccagg tgcaaaccca gataaagtta
    17641 aacaagaatt agcagaccaa ggattattag ttgaagactg gggtggagaa gtaatagcag
    17701 ttccagtatc agctaagaaa aaagaaggaa tagatacact tttagaaatg gtattattgg
    17761 ttgctgaaat ggaagagtta agagctaatc caaataaaag agcagtagga actgttatag
    17821 aagctgagct tgataaagga agaggaccag ttgcaacagt acttgttcaa ggtggtactt
    17881 taacagtagg tgacccaatc gttgcaggtg ttgcatgtgg taaagttaga gcaatgataa
    17941 atgcaaaagg taagagagta aaaacagcag gaccatctac agcagttgag atattaggtc
    18001 tatcagaagt tccacaagga ggagaccaat ttgtcgaagt tccaactgat aagattgcta
    18061 gaagtgtagc agcaagaaga caacaaatag ttagagatga aatgttaaaa tcaactcaaa
    18121 gattatcact agatgcttta tttagtcaaa tgagtgaagg ttctataaaa gaccttaata
    18181 tagttataaa agcagatgta caaggttcag tacaggcagt taaacaatct ttagaaaaat
    18241 tatcaaatga agaagttcaa gttaaagtaa tacatggtgg tgttggagct gtaacagaat
    18301 cagatatatt acttgcagca gcttctaacg caataataat aggattcaat gtaagaccag
    18361 ttccaggtgc agaatctcta ggagaaaaag aaaatgttga tataagaaca tatactataa
    18421 tatacaaggc aatagaagat atacaagctg ctatgactgg tatgttagac cctgaatatg
    18481 ttgatgaaga aacaggaaaa gctgaaataa gagaaatata taaaatatct ggtgttggaa
    18541 cagtagctgg atgttatgtg actaatggta agatatttag aaattgtaaa gtaagattag
    18601 tcagagatag cataataata catgaaggtg agcttgcagc acttaagaga tttaaagatg
    18661 atgtaaaaga agttaattct ggatacgaat gtggtatgag ttttgtaaat tataacgaca
    18721 taaaagaagg cgatatagta gaagcttata taactaaaga agtagaaaga aaattataaa
    18781 ttcgtatcaa agaaaatcag ttagtaaaga aggtcgatgg tatggcatca tataatagaa
    18841 caagaaggat atcagaagaa ataagaaaag tagtaagtac tatgcttata aatggagtaa
    18901 aagaccctag aataacatct atggtgagtg taactgatgt agaagttaca aatgacctaa
    18961 gatatgctta tgtatatgta agtattctag gtggagatga ggaatccaca ctaacaggtc
    19021 ttaaaagtgc tggaggatat ataagaagag aagtaggaaa aaatataaaa cttagatata
    19081 ttcctgagat agtatttaaa attgatgatt caatagaaaa aggaatgtat atggatagcc
    19141 ttataaaaag agttaatgaa aaaaatgctc aacaaaatga ggatgaaaat tatgatgaat
    19201 aatatggata gtattataaa ctatatttat gagggtgact attttatagt tacctctcat
    19261 atcagtccag atggagataa tattggctct acactttcaa tgtattatac attgaagaat
    19321 ttaggaaaaa atgtatatta tgtacttgat gatgaagcac cattaaatct aggatttttg
    19381 gttgaaggtg taaaaatcta taaatctaat gaatttaata tgaagaacta ttctataatt
    19441 gcacttgatt gtggagataa gatgagaata tgtgtgagtg atgaaatcaa aaataatgca
    19501 tcaaaattaa tttgtattga ccatcatgct agtaatgatt catatggaga tttaaattat
    19561 gtagatattg atgcatcttc tacatgtgaa ctagtttata atttattggt tagattccag
    19621 caaataaaag atattaatat tatcaatgaa gatatagcaa catgtttata tacaggtctt
    19681 gtaactgata ctggaaactt ttcatattca aatgcacatg caagtagttt tgaaatggca
    19741 aaaaatttac ttgttttagg tgcacaaaaa aatactataa tacaaaatat atatcaaagt
    19801 aattcatatg attattataa attattagga gaagctctaa aagctttgga gatatttaat
    19861 tcaaaggtat ctagcatagt tttaactcaa gacatgatga atagaaataa tattagcttt
    19921 aatgatgttg atggaataac aacatataca agagatataa aaggtattga agttggaatt
    19981 ttatttaaag agaaaaaaca aaatgaaatt aaagtaagtt ttaggtcaaa aaattatatt
    20041 gatgtaagtg aaatagccaa gttatttggc ggtggtggtc atgtaagggc tgctggatgt
    20101 actattagag atagtattga taatgcaaaa aaaatggtac tagaggcagt gttaaaatca
    20161 atttaaggtg acagtaaaat gaataagatt ataagtatat tgaaacctac aggtatgaca
    20221 tctcatgatg ttgtaagtag agtgagaaag attttaaata taaaaaaagt cggtcataca
    20281 ggtactcttg acccagatgc ttcaggtgtt ttaccaatct gtatagggaa agctacaaag
    20341 gtatgtgaag ttattttaaa caaagataaa tcgtatatat gtgagcttac cttaggtata
    20401 agtacagata cttatgatgc ctcaggtgaa attctaaaaa aagttgatga ttttaaattt
    20461 agtaatgaag agataaaaag agcttttgat acacaaagag gagagataaa tcaacttcct
    20521 ccaatttatt cggctttaaa ggtaaatgga aagagaatgt gtgatttagt aagaagtggt
    20581 agacaatctg aaatcacttt aaaaacaaga cgagtaaata taaaaaacat aaaaatacta
    20641 agtataaaag gtaataaagt aatgttttat gttgagtgtt ctaaagggac ttatgtgaga
    20701 agtatttgcc atgatatagg agaatatcta ggttgtggag ctcatatgtc gtttttgaat
    20761 agaacatctt ctggtaaatt tgatttagac aattcaataa cattagaaga attagaatta
    20821 ttttatgaaa ataaaacttt agacaaatac ttatatgata tagattatgt acttgattca
    20881 tttaattatg ttgtattaaa ctctaatgct ataaaatatt atagcaatgg tggttcaata
    20941 gatgacaaaa ggtttttaaa aaataatttc aataaagatg atgaatttgt aagagtatac
    21001 agtacagata atttcttagg attaggaaag ttgtcaaaac acaataatat aataagtgtt
    21061 aaaagtgata agatgttcat ataaataatg tatttaaaaa acaacaaaag agatagtact
    21121 ataataactt ctatagtcta tctcttttac ttatgctata atagtttgtg aataagttaa
    21181 gagtaaatta tattttagcg gggaacattt attatggaga ttataaaatc tataaaagaa
    21241 atagcaaaca taaaagaaag tgtcattacc ataggaaatt ttgatggtgt acacaaagga
    21301 catcaagttc ttataggaaa aacagttgaa catgcaaaaa aagaaaatat acagagtatt
    21361 gtatttacat ttgcaaatca tcctgtaaat tactttagac caaactcaac aaaaaatatt
    21421 ataagcaatg atgataaaat aaaattatta gaagatttgg gaatagatat agttgtaatc
    21481 ataccatttg atgagtatat gactaaaata cctgcaaagg attttgtaga tgagatacta
    21541 gtaaaaaaat taaaagctaa aaagatagta attggacatg actttacatt tgcaagggca
    21601 aaagaaggca atgttaatct attaaaaagc ttagaacatg aatttggttt tgaggtagaa
    21661 gtaataaaac caatcaaaat caatgatgta agagtgagta gtacttatat tagaagttta
    21721 gtatcccagg gtgatatggc tagtgtcaag gaatatttgg gaagaaatta caagttagaa
    21781 ggttgcgtta tacattctaa acatcttgga agaactatag gattcccaac agcaaatatt
    21841 gaccttaaga ataatatgct cgttccaaag agaggtattt atgcttccat tgtacatatt
    21901 ggagatgaga cttattttgg tgctacaaat gtaggctata acccaacagt taatggaaaa
    21961 actttgtcta ttgaaacaaa tattttagag tttgatagag atatttatgg agaaaatata
    22021 attgttgaat ttttggaaag aataagagat gaaagaaagt ttaattcaat agatgactta
    22081 aaaaatcaat tgtataatga tacaaattat gtgtatgaaa actatgtttg caaaaacaag
    22141 taatgtatga taaaatgatt aaggaaaata accattactc ggcatttgaa tactccaatc
    22201 aatgcttagt aataggcgtt tctaaaaaaa tacggaggta atctaaatga taaacaaatc
    22261 agaaataata aaagaatatg gaagagctga aggagatact ggttctccag aagtacaaat
    22321 agctttatta acagctagaa taaacgagtt aaatggacat ttaaaaactc ataagaaaga
    22381 ccaccattca agaagaggtc tattaaaaat ggttggtaga agaagaaact tattagctta
    22441 cttaaaggaa aaagatcttg aaggatatag agcattaata gctaaattag gattaagaaa
    22501 gtaatttcat tctttataaa aaagcaggta tagtgtatac ctgctttttt atagttaatt
    22561 cattataaag taaaatagtt aataataaaa gtagtttata tgttataaaa aattataaaa
    22621 tgaataatat tgggtaagaa tattaaaata gtatacaaat acataatcaa tttaaaagga
    22681 aagataggac aaatatagaa attttataac aggataatta gttagaataa ggaggatatt
    22741 attttgaaaa taaagttagt atgtgatagt ttatgcgata ttccagatga aatatcagaa
    22801 aaagattata tagagatagt tccacttaca gttattttta atgataggga atatatagaa
    22861 ggagtagata taaagaaaga agagttttat aaaaaagtaa aagaaattaa acaaatacct
    22921 aaaacttcac aagctacata tatggagttt aaagaagtat ttgataagtt catagcagaa
    22981 ggttatcata taatctgtat gacaggggct gcaaacgcat caggaacttt tcaaagtgct
    23041 atgatagcta aaaatgatgt agatgaaaat gaaaaaatac atatatttga tactagaaat
    23101 ttatctctag gtagtggaca atatgttata aaggcatgtg aacttcttga agaaggactg
    23161 ggatttgaaa aaattataga tgaattagaa aatactcgaa gtagtgtaag attacttttt
    23221 gcaccatata cacttgattt tttaaagcag agtggaagag ttccagttgc aactgctttg
    23281 ataggaaata tgttaaatat aaagcctata tttttctttg ataatgggga agctaagttg
    23341 gtaaataagg ttagaggtat aaaaaatata gcaagtaaat tggtcgatat aattttagaa
    23401 atgaatgaag ggtctttaga aggaaaaatc atcacaatag gttgtggaga taatttacat
    23461 gattgtgaaa tattaaaaga tgaagtaaat aaaagaataa aagcaagaag cgtattattt
    23521 actcgaggag gagtttctat ttgctctcat acagggccag atatattggc tataagttgt
    23581 tctaattagt agtaatataa ggtttttgca tatatatgtg aagataattt tatattgtta
    23641 atttatagta tttttgataa tatagtaaat agagtgatat acgtgttttt taataagagg
    23701 aggacaagca ttaatgtttg aacataaaat atttaaaatg gattttgcag gaagagaact
    23761 ttctgtagaa ataggaaaga tttgtgaaat ggctagtggt agttgtatag ttcgatacag
    23821 tgacagtatg gtaatggtaa atacaactaa atcagccaaa cctagagacg gaatagactt
    23881 ttttccttta agtgtggatt atgaagaaaa attatactct gtaggtaaga tacctggagg
    23941 ttttttaaag agagaaggta agccttcaga aaaagctata cttacatcaa gattgataga
    24001 tagaccaata agacctttat tcccaaaagg atttagaaat gatgttcagg tagttgcaac
    24061 agttctatca gtagaccaag attgcacacc agatatagta gcaatgatag gttcttcaat
    24121 agccctttct atatcagaca taccatttaa tggaccaaca ggttcagtat gtattggcct
    24181 tgtagatggt gcatttgttg taaatccaaa cgcagagcaa agagaaaaaa gttcaatgca
    24241 tctagttgtt tcaggtacaa aggaagcaat aatgatggtt gaagcaggag ctgacgaagt
    24301 tccagatgag gtaatgcttg atgctatttt atttgctcac caagaaataa aaaaaatagt
    24361 tgagtttata gaaggtatag ttgcagaagt tggaaaagaa aaaatgcctg ttgaattata
    24421 ccatgcagga gaagaaataa ctcaattggt tcgtgaattt gcaactgata agatgaaaaa
    24481 agcagttcag acttttgaaa agttagagag aatggaaaat atggatagag ttaaagaaga
    24541 aactttagct cactttgaag agactttaga agattttgaa gattttgttg gagatataga
    24601 agaagtatta caagatataa taaaagaaga agtaagaaaa cttatagtac atgaaaatgt
    24661 aagaccagat aatagaaaac ttgaagaaat aagacctata tggtgtgaaa ctggcatgat
    24721 acctagagct catggttcag ccatatttac tagaggacaa actcaagtac ttaatgttgc
    24781 tactttaggt gctttaggag atgttcaaaa attagatggg ttagatgaag aagaaaacaa
    24841 gagatatatg catcattata atttccctgc atatagtgtt ggagaagcta gaccatcaag
    24901 aggaccagga agaagagaaa taggacatgg tgctctagca gaaagagctt tattaccagt
    24961 aataccatct caagaagaat ttccttatgc tattagatta gtttctgaag tattaagttc
    25021 aaatggttct acatctcaag caagtgtatg tggctcaaca ttatctttac ttgatgcagg
    25081 tgtacctata aaagatatgg ttgcaggtat agcaatggga cttataaagc atgatggtaa
    25141 ggttgcagtg ctttcagata tacaaggtat ggaagaccat ttaggtgata tggactttaa
    25201 agtagctgga acagagtatg gtataacagc aatacaaatg gatataaaaa ttgatggtat
    25261 agataaagaa attctacaac gtgctttaaa acaagctaaa gaaggtagaa tccatatact
    25321 aggagagatg agaaaaacta tatctcagcc aaaaccagaa ctttcaccat atgcacctaa
    25381 gattgttaaa atgcaaataa atcctgacaa gataaaagat gtaataggac ctggtggaaa
    25441 gataataact aagataatag acgaaactgg agttaagata gatattgaac aaactgggga
    25501 agtatttata tcaggtattg agattgatat gattaagaaa gctcaagaac ttataaataa
    25561 tatagtagta gaaccagaag taggaaaaac ttataaaggt aaagtaagta gaataatgaa
    25621 ctttggagca tttgttgaga tacttccagg aaaagaagga ttacttcata tatctcatat
    25681 agctcatgaa agagttgcta aagttgaaga tgtattgaat ataggggatg aagttgaagt
    25741 taaagttaca gagattgatg aaaaaggaag agttaattta tcaagaaaag ttcttttacc
    25801 aaaaccagag cataaaaata aataatttat taaataataa aaagcaaagt cttaggattt
    25861 tgctttttat tatttggtgc ataaacagag cttattttta atagtattaa ataagaaaca
    25921 atttgtacat aattaggggg agttttaatg ataatgatgg tacttaataa gagtaagctc
    25981 aaaaaaatca taatactaat tttagtagtg ttattagtat tatcaggagg ggtaatggta
    26041 ttaaagttat ttaacaacaa gccagtattt aatttattta atggtgtaga tttaccatat
    26101 gaaagaggta caaaggatga aagtggatac gttgcattaa cctgtaatat agaccttgga
    26161 tgggaaacag agtacgtaga atccatttta gaaacactta aaaaagaaaa tgtaaagatt
    26221 acatttaatg taaccggaaa atgggcagaa aagaataagg acgaattatt aaagataaaa
    26281 aaacaaggac atgaaatagg taatcatgga tacaaacatt tagattactc tacattatcc
    26341 tatgaagaca attatgagca aatagagacc tctaaaaaga taattgaaga aattataggt
    26401 gaaaaaacta aattttttca agcaccagca ggttcttttg gtccagaaac agtaaaagct
    26461 gctaaagcat tagggtatac ttctatcaaa tgggatgccg atactataga ctggaaatac
    26521 aaagaccaac cagaggtaat cattgataga atgaagaaaa aagatattaa agatagtagt
    26581 ataatcttaa tgcacccaac caatgcaacg acaaaatgta tagatgatat tatagctatt
    26641 gtaagagaaa aaggactaaa accaggaaag cttagtgatg tatttaagta gacaaagtat
    26701 aaatatttgg ttaagattgt ataagttgta gttgaattaa ttaaaagact gacttataat
    26761 gtaatacata taaaaaataa atataattaa aacatagtgt tttcaataat ccaatatgaa
    26821 acaaagaata aattgttagg agaatgtaat gtataagaca aaaatactgg aaaatgggct
    26881 tacaataatt ggtgaagaaa taccatatct aaagtcaata acattaggta tttggataaa
    26941 tgcaggctct aggatagaag aagcacaggt gagtggaact tctcatttta tagagcatat
    27001 gatgtttaaa ggaaccaaaa acagaacatc aaaagagatt gctagctcaa tagataattt
    27061 gggtggtcaa ctaaatgcat ttacaagtaa agaatgtaca tgttattatg taaaactaat
    27121 agatgagcat atagatatag gaattgatgt attaagtgat atgatactaa attctaaatt
    27181 tgataaaaat gatatcgata aggaaagact tataatattg gaagaactta agatgtatga
    27241 agattctcca gatgacttat cttatgattt attagtggaa aatatatatg ctaatgatgg
    27301 attaggaatg aatataattg ggacaaaaga atctctatac aatataacta gagagtctat
    27361 gttagaatac ttaaataagt attatattcc aaataacgct gttatttcta tagctggaaa
    27421 ctttaacttt gatgatatgg tagagaaaat taaatcaaaa tttggacact gggaaaagaa
    27481 aaatttgagt atagacataa gtgaggctaa gtttaatcct tgctttatat caaaaaataa
    27541 agatactgaa caggtgaact tagctatgtg cctaaaaggt attccttttg aaaatgatga
    27601 agaagtctac tcaatggcag tggtaaataa tatttttggt ggaagtataa gctcaaggct
    27661 ttttcagaaa ataagggaag aaaaaggttt agtatattca atatactcat cacagacatt
    27721 atatagaaaa tgtggtgaat taggtatatt tgcaagtatg agtacagaaa atttacaaga
    27781 tgtgtataat ttagtaaaaa aagaaattga aaatataaga gaaaactatc ttaccgaaga
    27841 agaaatatct gaaagtaaag aacagttaaa aggcaattat atattggatt tggaaagtac
    27901 tagcagtaga atgatgtcta ctggtaaatc tatgttactt agtaaaaaag taaaaactac
    27961 agatgaaata cttgaatgta taaataatgt tgatattaat tcagtaaaga aagttgttga
    28021 taaggttttc aatgtcgaga atattggtac atgtatagtt ggaagagatg tggaaaaaat
    28081 tctacacttg aattaatatt gtaaaaagta aatctctgga ggtataaaat atgaatttat
    28141 ctgaaatagc aggtaaggaa atagttaact tggtcacagg agaaagattg ggggtcattg
    28201 gagaatgtga ccttatacta gatgaaacta caggcggtat attagcgctt ctaattccaa
    28261 aagaaaaagg attttttgcc agaagaaaag ataagtcatt tttagaagta ccatggagaa
    28321 atgtaaaaaa aataggtaat gacatgataa ttatagaata tgagggatat atttaggagg
    28381 aaaaaatgag tattttagtg caaaagtttg gtgggacatc agtagaatca tatgaaaaaa
    28441 tgaatgaagt atgtaagata gtaaaagcat acaaaaaaaa tgatgaagaa ttacaattag
    28501 tactagtagt ttcagcaatg ggaagaaaag gagctccata cgctacagat acacttataa
    28561 atttatgtag tgcagtaaat gatgagccaa gcaaaagaga acttgattta ataatgtctt
    28621 gtggggaaat aatatcagga acaattcttg ctaatttatt gaatgcacag ggtatagatt
    28681 ctgttttctt tactggtcag caagcaggta taattacaag tgatgaatat tctaatgcaa
    28741 agataaagta tataaatcct aaaaagataa aaagagcttt agatgatggg aaggttgtag
    28801 ttatagctgg attccagggg gtaacagatg atggagaaat aactaccctt ggaagaggag
    28861 gaagcgatac atcagcagtt gctattggta aagctttaga atgtgaaaca gttgaaattt
    28921 acactgatgt ggatggtata atgactgcag accctagggt ggaaccaaac gctaaagtat
    28981 tgagttttat agattatgag gaagtattcc aaatggctga caaaggtgca aaggtaatac
    29041 atccaagagc agtgcaatta gctaaaagtg gaaatataac tttggctata aaaaatacaa
    29101 tgaacccaac ttttgaaggt acaaaaatag gttctttatg tagacactta gaagataata
    29161 tagaatatga acaagaaaga gattttaaag ttgctgttgc aaataaagat agtgtagcac
    29221 aagttaagat taagtcagca gaagaagtgt ttacagaagt attaaatgag atagaaaaga
    29281 aatttataac tatagatatg ataaatttct tcatatcaga aaaagcattt gttgtagaag
    29341 atgctgatat aaaatcattg aaggaaatac tagataaatt tgaattggat tatgaagtaa
    29401 atagagactg tgctaaggta acattgatat gttcaagaat tgctgatgaa atgtctggta
    29461 tcatgtcaaa ggtagttaga ggattatcaa aagcaggggt atctctttta caaacatcag
    29521 actcaaatat gactatatct tgtttagtta gtgaagaaga tatgcataca gcagtacatg
    29581 ctatacacca acaattttat ttaaaataaa caatataata caattatttt ttaatcaaat
    29641 ttgataattt catatatatc ttaatatatt tgatttattt ggtaaaacta aattaaatat
    29701 gattttgata ggagtttttt ttatgaaaga ttatagagaa gataatgaaa gatttgataa
    29761 agataattgt agtgaagaat ctagtagtga agagagagaa tgtataaagc aatttggtac
    29821 caatgaaatg ccacctcaac ctcctaagga tattcaatgt ataactataa ttggagaaat
    29881 tgagggacat tttataggaa atcctcaaaa aaaagctaca aagtatgaac atataattcc
    29941 aatgctgtac tcaattgagg aaagtaatga tgttaaagga gtattagttg ttttaaacac
    30001 tgttggagga gatattgaag caggtttagc tattgcagaa cttttaaaca gtacatctaa
    30061 aaaagtagtt actcttgttt taggaggaag tcatagtata ggagttcctc ttgctacagc
    30121 tggagattac tcatttatag caccaacagc aaccatgatt atacatccag tgagaactac
    30181 tggtcttgta attggcataa atgagacttt tgaatatttt aaaaagatgc aagatagaat
    30241 aattcaattt ataataagaa catcaaatat caaaaaagat gtacttgaaa aacttatgca
    30301 tgaaaaagat gaacttgtaa gtgatgttgg tagtgtatta ataggaaaag aagctgtgga
    30361 ttatggtctt atagatgaag ttggaggact aaaagaagca cttaaaaaat taagagagct
    30421 tataaaagaa tctgaggaag aaaaaaataa tgattaaaat ttgtttaaat aataaaattt
    30481 atgatataat gatgtaataa agtaggagtg ttagtgttaa ggcattagca ctttttgctg
    30541 tgaaggggta aaacttgcta aaaataagga gtgatattaa tggccacgaa aaagaagaaa
    30601 aaaaagaagg taaatacctt aagttttaat gcagaatatc ataatttaat aacaatattt
    30661 ataggtgtat ttttattata tagtttaaat tctaattcta tgggatggat acctgtgtta
    30721 atgcaaaatc tttttaaggg actatttgga gggctttcaa tagcaatacc atttatagta
    30781 attataacag gacttttagg attttttgat ggaaatgaat atatatatag gctaagaaag
    30841 actaaattat actacataat tattttattt atatttgtat tttatggatt attaaatgca
    30901 ggtactcttc ctgtagatag cccactaaaa ggtaacatgt ttgatgatgt tatgaaattg
    30961 ggtgtaagtg gacaaggtag tggcttgata gcaacaacta ttgcgtatta tatgagtaaa
    31021 atatttggta tagtaggtgg atggttaata agtatctttg cacttatact ttctgtaatg
    31081 tttatattta atatttctat aaaagatatg atatcaaatg caaaatcaaa atctaaagca
    31141 tcaaaagaca gcaatttaac gtttaaagat aaaattgcaa atatgaaaaa atctgcaata
    31201 gatatgatga ctgatgaagt agatgatact actataaata aaaaaccagg tttctttaaa
    31261 gggttaatgt caaaaggtcg taatactgat gaagaagatg aatattttga agaagaaaat
    31321 agtgatggtg tagatgataa gactataaaa atagttggat ttaataaggc agaagatgag
    31381 tatttagaga tattagaagg aactcaaagt atgccagagt tagatgtttt aaaagaatta
    31441 caaaaagcta caaatgaaaa tccagttata gacactaaac cagaaaaaaa agttgatata
    31501 gctaagccta acttaaatat agaaaaaact caacctatga gtattgtagc agagccagtt
    31561 aatgaggatt attcaaacta taagaagcct agcattgagc tcttaaataa agtaaataag
    31621 aagtctgatg aaaatggtaa aaagaaagtg ttaaaaaatg cttctctttt agaaaagaca
    31681 ctatcagatt ttggagtgga agcaaaaatt aatcaagtta cagttggacc tactataaca
    31741 aggtatgaaa tacaaccaag tccaggagtc aaggtaagta aaatcgtaaa tttaactgat
    31801 gatatagctt taagtttagc agctaaaagt ataagaattg aagcaccaat tcctggtaaa
    31861 agtgcaattg gaatagaagt tccaaatgaa gaagctcaaa tggttggtgt gagagaagtt
    31921 ctagaaagtg aagaatttaa taattttaac tctcctcttg caatgggact tggaaaagat
    31981 gtagcaggaa aaattataat tggagatata ggtaagatgc cacacttact aatagctggt
    32041 tctacaggtt caggaaagag tgtatgtgta aatacattaa taagtagtat tttatataag
    32101 gcaaatcctg atgaagtaaa attactatta atagacccaa aagtagttga acttgcaaat
    32161 tataatggga tacctcatct gttgatacca gtagttactg accctaaaaa agctgcaaat
    32221 gctttaaact gggcagttac agagatgaat agaaggtaca agctatttgc agatgctcaa
    32281 gtaaaagatg taacaagtta taatgagaaa gcagaagaaa aacttcctaa aatagtaata
    32341 ataatagatg agttagcaga tttaatgatg gcaagtgcaa atgatgtaga agattatatt
    32401 tgtagactag ctcaaatggc aagagctgct ggaatgcact tgattgtagc aactcaaaga
    32461 ccatctgttg atgttataac aggggtaata aaggctaata taccatctag aatagcattt
    32521 gcagtatcat ctcaaactga ttcaagaaca atccttgata tgggtggtgc agagaagctt
    32581 ctaggtaaag gtgatatgtt attctaccca cttggtgcag caaagccagt tagacttcaa
    32641 ggtgcattca tatcagaaag tgagtcggaa aaagtaattg attttgtgaa aagtcaggtt
    32701 aaagatggaa taaaatatga agaagatata attgaaacta tatctaaggt taatacttca
    32761 aagggtagcg atgaggatga gtttttgagt gaagcgatag aatttgttgt ggaaagtggt
    32821 caagcatctg cctctatgtt acagagaaga tttaaaatag gatttaatag agcagctaga
    32881 cttatagact ctatggaaga aagaggaata attggagcaa gtgagggaag taaaccgaga
    32941 aaggtattaa taagcaaaca ggatttgcag aatttagaag gtgaatagaa ttgtcagtta
    33001 taaaaataga aaaagcactt aagctagaca aagtaatatt tgtagatgta agaactgaag
    33061 gggaatatga agaagaccat atattgaatg caattaatat gcctcttttt aaaaataatg
    33121 aacataatga agttggaaca atttataaaa tgcagggaaa acatgaagca atacaaaagg
    33181 ggtttgacta tgtatcttat aaattaaagg atatatattt acaagcagca gaacttgctt
    33241 taaattatga taatattgtc atatattgtg caagaggtgg aatgagaagt ggaagtatag
    33301 taaatttatt atcatcatta ggtgtaaatg tatatcaact tgaaggtgga tataaggctt
    33361 atagaaattt tgttttagag tatttaaggc atgtaatgga tacaaaaaac tttgtatctg
    33421 ttcatggact tactggtaca ggaaagactg atttactaca tttattagat gaaaaaggaa
    33481 tagatgtact agatttagaa ggcatagcta aaaacagtgg ttctaccttt ggttttataa
    33541 cgtttgataa aaaaccacca tctcaaaaga actttgaaac aaaattattt gaaagtatat
    33601 ttttctcaaa agagaattat atctttgtcg agagtgaaag taaacgagtt ggaagtgtta
    33661 caattccaaa tgaaattttc gaggcaatga cacgagaagg acatcatata ttattagaat
    33721 gtgatattga aaatagagtt gatagacttt gtagagatta tatttatgat aaagatgaag
    33781 gtaatctatt ggttttaaaa gaatgtataa acaaatttag aaaaagattg ggtcataaag
    33841 tagtagatga ttatattgat ttattagaat caggtgaata taaagaactc gtaaaaagat
    33901 atcttttaga atactacgac ccactttata tgcattcagt agagaaatat aagtataata
    33961 aggttataaa ctttaatgat acagaagaag ctttagaaga tgttatagac ttatatgaga
    34021 gtatattgga aggagaaaat gaatgttaaa aatagcatta gaatcattag gatgctcaaa
    34081 aaatttagta gatgcagaaa taatgatggg aattttaaat aacaaaggct ataaattaat
    34141 tggagatttt gaagaagctg atgtaatcat agtaaataca tgtggattta tagagtcagc
    34201 taaacaagaa tctatagata cgataataaa ctttgccgaa ttaaaaaaaa ctggcaattt
    34261 aaagttgttg atagtaacag ggtgtttagc ccaaagatat tctgaagaat taaaaactga
    34321 aattcctgaa atagatgcta tagtaggtac aggaagctat caaaatatag ataaaatact
    34381 tagagaatta agtgaaatgc atcaaattgt aagccttaat gatatagagt ttgtatttaa
    34441 tgaagattta ccaagatatc tatctacacc tagctatatg gcatatttaa aaattggaga
    34501 aggatgctcc aataattgta cttattgtat aataccaaaa ctaagaggta aatatagaag
    34561 tagaaaattt gaagatataa ttaaagaagc taagaaatta gctgaatctg gagtaaaaga
    34621 acttgtagtt atagcacaag atacgacaaa gtatggtttt gatttatatg gaaaagaaag
    34681 attatcagaa cttttagaag aacttgcaaa gatagatgga tttaagtgga taagagttat
    34741 gtactcatat ccagaatcta taacagaaga attaatacaa gttataaaga aatatgataa
    34801 tatatgtagt tactttgata tgccaataca acatgcaagt aacaatattt taaaattaat
    34861 gaatagaaaa actactaaag aagatatatt aaataaaatc aatcttataa gaagtaatat
    34921 accagatgct atacttagaa ctactataat agtaggattt cctggcgaaa cagaagatga
    34981 ctttaaacaa cttgtggatt ttgttgaaga ggttaaattt gatagacttg gtgcatttgc
    35041 atattcaaga gaagaagata caccagcaga tagattgcca aaccatatag atgaagacgt
    35101 aaaaatacaa agaagagata ctttaatgat gattcaacaa aaaatatctg aagaacttaa
    35161 tgacaaaaag ataggaaaaa cttatgaggt gttaatagaa gaacagatag aagataatgt
    35221 atatacagga agaacacaag gtgatgcgga agaaattgac agtatagtgt atgtgaaaag
    35281 tgtagacaat cttgaaatag gagaatttgt aagtgttaaa ataaatgatg caatggaata
    35341 cgatttaatg ggagatgttt tatatgaact tgcctaacaa gttaactttg tttagaatat
    35401 ttttaatacc agtatttgtc ttaattatgt tgctcaatat accaaataaa tttttaatag
    35461 cttgtattat ttttataata gcttcaatta ctgatgcttt agatggaaaa atagctagaa
    35521 aatacaatct agtcactgac tttggaaaat ttatggatcc attagcagat aagctattag
    35581 ttatttcagc acttacatgt atgatagaag accatcttgt aagcagttgg atggtaatta
    35641 taatagtggc tagagagctt acagttagca tattaagagc tatagctgct gctgatggaa
    35701 aagtaattgc agctggaaac agtggaaaac ttaaaacgat aactcaaatg gtatctatag
    35761 tgcttttatt gttaggtgct cagtttgcaa atggattgat attaaatatt ggtgaaattc
    35821 tcattcttat agctactcta cttacattat attctggatg ggaatattta tataaaaata
    35881 aagagctctt tatgtcttct aagtaaaaaa ttatgcttta ataaataaaa attaacaact
    35941 taaaatttta aaaatgtaaa aaagggtata ctattatagt atatctcttt tcattttaag
    36001 aatattttct tttgtgtata taattattaa taatggttta taaataaaat gtaatgaata
    36061 aaaatataat cattagtagc gtttttaaat tgactaggtt tgatttatgt tatataatta
    36121 atatataaca agagaacaaa tgtttgtaga taaatgaagg gatggtatag agatgagtgt
    36181 agatcaagaa aaattaaaag cgttgaatga agctttaggt aaaattgaaa aagattttgg
    36241 taaaggttca gtaatgaaat tgggagaagc aacatctatg tctatagatg ttatatcaac
    36301 aggagcgatt ggtttagata tagctattgg tataggaggt ctacctagag ggagaatagt
    36361 tgaagtatat ggtccagaat cttctggtaa gactactgtt gcacttagtt gtgtagcatc
    36421 agctcaaaaa gatggaggaa tagctgcatt tatagatgca gaacatgcac ttgacccagt
    36481 atacgcaaaa gctttgggcg tggatgttga taacctaata atatctcaac cagatacagg
    36541 tgaacaggct ttagagatag cagaggcatt gataagaagt ggagcgatag atataatagt
    36601 aatagactca gtagcagcat tagttccaaa ggctgaaata gatggagata tgggtgactc
    36661 tcacgtaggg ttacaagcta gacttatgtc gcaagctctt agaaagttaa ctggttcaat
    36721 taaaaaatca aattgtgttg ctatatttat aaaccagtta agagagaaag taggaataat
    36781 gtttggaaac ccagaaacta ctactggagg acgtgcatta aaattctatt catcagttag
    36841 attggatgtt agaaaaatag acacaataaa acaaggagat aaagttatag gtagtagaac
    36901 tagagttaaa gtcgttaaaa ataaagtagc acctccattt aagcaagctg aatttgatat
    36961 aatgtatgga gaagggattt caaaaattgg agaccttcta gatatagctg ctgatgtaga
    37021 tatagtaaaa aaatcaggtt catggtatag ttacaatgat actaaacttg gacaaggaag
    37081 agaaaatgtt aaaaaattct tggaggataa tttagattta actaatgaaa tagatgagaa
    37141 agttagagca ttttacaatt taaatgaaga acatgaagaa gcaggtaatt cagtatcaaa
    37201 agaaattgta gaagaataag taaaaataca aaaaaataac tagtaattaa agacatgcca
    37261 cgctccctat tagcttgaca caatgttgaa aaaattataa aattaagtga ggataaaata
    37321 tctaaattta attttaatta ttaggaatat tttttaatca tagtgatgac attttgggat
    37381 tattaacgaa ggaggtggat gtcatagata gtgtagtaat gattgtaata ggtgcagctg
    37441 ttggtattat agctggatat tttgttagaa aaaatatatc tgaagcaaaa attggacaag
    37501 ctgaaaactt ggccaaagaa ataatagata aagcacacca cgactcagaa acagtacaaa
    37561 aagaaaagtt actagaagct aaagaagaga tccataagtg gagaacagaa gctgaaagag
    37621 aaaacagaga aagaagaaca gaagtacaaa agtatgaaaa aagagtagta caaaaagaag
    37681 aagtattaga tagaaaatta caaaatttag aatctaaaga agtaaaccta agtgaaaaat
    37741 taaaggtagt ggaaaagaaa gaagaagaag ttgaagtaat aaaaactcaa cagctagaaa
    37801 aattagaaag tatatcagga attacttctg ataaggcaaa agaaatcatc ttaaccaatg
    37861 cagagagaga tgtaagacgt gaaatgtcta taatgataaa agagatagaa agtcaagcta
    37921 aagaagaagc tgataagaaa tcaagagaaa ttataggata tgcaattcaa aaatgtgcag
    37981 cagatcacgt agccgaaact actgtcacag tagtaagctt gcctaatgat gaaatgaaag
    38041 gtagaataat aggtagagaa ggtagaaata taaggacttt agaaacctta acaggtatag
    38101 accttataat agatgacact ccagaagccg taattttatc aggatttgat ccaataagaa
    38161 gagaaattgc aagaattgct ctagaaaaat taatagcaga tggaagaata catccagcta
    38221 gaattgaaga aatggttgaa aaggcgagaa aagaagttga caatattata aaagaatatg
    38281 gtgaacaagc tgcatttgaa actagtgtac atggaattca tccggaatta ataagattat
    38341 taggtagact taactataga actagttatg gacaaaatgt acttaaacat tctatagaag
    38401 ttgctcatat agctggtata atggctgctg aaataggagc agatattaga ttagctaaga
    38461 gagcaggttt attgcatgat ataggtaagg ctgtagacca tgaaatggaa ggtacacatg
    38521 ttgaaatagg tatggattta cttagacgtt ataaggaatc taaagaagtt atacatgcca
    38581 tgagtaccca tcatggagat tatgaacctc aaacagtaga agctgtatta gttacagcag
    38641 cagatgcaat atcagctgct agacctggag ctagaagaga aactttagaa gcatatataa
    38701 agagacttga aaaattagaa gaaatagcta attcatatga aggtgtggaa aaatcatttg
    38761 ctatacaagc tggtagagaa ataagaataa tggtaaaacc agaagctata aatgatgaag
    38821 aaatacacct attggctaga gacatgacta agaaaataga ggatgaactt gaatatcctg
    38881 gacaaataaa agtaagcata ataagagaaa caagagctat agaatatgcg aagtaaaaga
    38941 aataatatct aaataataag aaaatatttt tagaaattta aatttgccac aagatataat
    39001 atatcttgtg gtttttaaat tgtttaaatt taattttata taatgtaaaa taatctaagt
    39061 gctaaaagtg ttacttacaa taaattaatg aaataaagat ttatatatgt attgtttata
    39121 taattatcca aatttgtttg atataatgaa gttgtaaaat aaatatatta ctacttggaa
    39181 tgcttatact taaataatat gaaaatacaa taaagctaaa gtgaggttta aagagagggt
    39241 acactatgaa aaaaaataca cttttacata caaatattat ggtttgcatt attattactc
    39301 ttggttttgt ggctacctct ataattggat accaatctaa taccaatatt tttaaaaatg
    39361 atattgaaca tgtgtctaca ttggctgctg aaggtattta ttatcagata gataaactac
    39421 tttcagaacc tataaatgta tctcttacaa tggcaaatga tagtttatta aaaaattttt
    39481 tagatggtga gaaagaacat ttaaatgatg aagaatttat ttataaatta caagattatc
    39541 tgaatgtata tagaaataaa tacttatatg attctgtttt tttagtatca actaaaacta
    39601 ataattatta tcattttgat ggacttaata gaaatcttag tgtcaataat tcagagaatc
    39661 aatggtatta tactttctta aataaagagg atgaatactc attaaatgtt gataatgatg
    39721 aagcaagtga caatagtatt acagtatttg taaattgtaa gataaaagat gataatggag
    39781 caactatggg aattataggt gttgggttaa aggttaattc attacaaatg ttgcttaaag
    39841 gatatgatga caaatttgat gttgtcactc acttaattga tgataaaggg tttgtacaat
    39901 tagcagtaga taaaactggt catgagcata taaatttttt tgaaaattcc agtagtgact
    39961 tgtctaattc aaaaaaatta atattaaaca atgaaaagga acaaaaaagt ttttggtatt
    40021 catctgaaaa atcaaaacgt tatattgtat gccagtacat acctagttta aaatggtatc
    40081 ttgttttaga aaatgatttt actttaatga gtaaacagct ttatatgcaa tttttaaaag
    40141 acattggagt tatagtttta attataatat ttgtactttt tactattaca catgtgctta
    40201 aaaaatacaa aaaacaaata gtgaagctta gtgtttcaca gaaattagaa tatcaaaagt
    40261 tgttaagcca atctactgaa ggactttatg aaaatatttt tgaaattgat attaccaata
    40321 atagagctgg ttgtgaagat gagaatagat attttcatga atttggatta gggcttaaca
    40381 ctccatatga tgaagcactg cacacaatag ctaaaaacca aatcaaagaa gaatatgcac
    40441 aaggttattt agatacattc ttacctgaaa atgtgattaa atgttacaat agtggaatta
    40501 ataatatcag ttatgacttt ttaattaaaa aagatgaaga aagctatcat tggattagaa
    40561 ttaatgcacg aattttcttt tggacatcag atgaatctgt tcgtatgata tcttatcgta
    40621 aaaatataga tgaagaaaaa aatagagaat tactacttct cgaacgttca caacgtgatt
    40681 ctcttacagg gctttacaat aaagctacaa cagaggaatt tattcgttca tttttaaaaa
    40741 atgaaagtaa tcaagactta gaacacgttt ttctaatatt cgatattgat gattttaaaa
    40801 atgtaaatga taaatatggt catgtatttg gagactttgt tataagtgaa tttgctttag
    40861 aattaaaatc tcaatttcgt gaggacgata ttgtaggacg tattggtgga gatgagtttg
    40921 tagtattaat aaaagacttt aatagtaata actatgtact tatagataaa ttagaacgtt
    40981 tttgctctaa gattaatcag aaaaaatttg ctgagcaagc aggattttct attggatgta
    41041 gtattggtgt atcaatgtat cctgaacatg gatatgtata ctctgaacta tatgagaaag
    41101 cagaccaagc actttactat gcaaaaagcc atggaaaaaa ttcttatcat gtattttcag
    41161 aggattctac tgatagtatt tcatttcata tagaccctag agacataaaa gtattattag
    41221 aaatggctac tgatggtgtt gtcaaatttg cttgtatgga aaacttaaaa ctactttatt
    41281 ttaaccaaaa aatgcttgaa tttactggat attcagctca aactgttact tctacagatt
    41341 ttaatatttt ttcgcctgta ctacaagatg acctacaaat ggtactcgat acattaaaag
    41401 aagcaatctc taaaagggag acttttgagg tagtttttcg tttttgtcat acagatggtc
    41461 atatttttcc tgtaaggatg caagggaagt ttgtaagtga attatatcaa aatcgttatc
    41521 ctgtttttta tgctatttat acagatatat caaatatcaa tactttatta gaaaataaat
    41581 agtaaatgct acagtaaaat ctaaaaatag gatataataa tattaatata agaagattat
    41641 aagtaaaacc tgctgataaa atagattatt ttaggcaggt ttttaaattt tttatagtaa
    41701 atcttatttt tagtcaatag ggtttatttt ttaagaactt tattgattaa aaaatagcta
    41761 cgcacacttg tgactttagt catgagttag tagctaaatt agtcagcata taggg
//
LOCUS       DBGJFK010000030        40931 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.030, whole genome shotgun sequence.
ACCESSION   DBGJFK010000030 DBGJFK010000000
VERSION     DBGJFK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40931
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.030"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            169..957
                     /locus_tag="ACOIAP_001862"
     CDS             169..957
                     /locus_tag="ACOIAP_001862"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2638748.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEAIKDDMMFISENGTLVVYKGKEILSNPLDKELVNEIIETTRSIEGKKI
                     VMSGKKYAYIESKDEAFIDEVSTYYAKFKVVDDLTKVEGDILKIAIFDFKGAEHNNSI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEYLKEIARFRAKRNTENGVVDKIKEVMKIG"
     gene            complement(1088..1558)
                     /locus_tag="ACOIAP_001863"
     CDS             complement(1088..1558)
                     /locus_tag="ACOIAP_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HGZ2638749.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEYIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENAPQIENKILSIIKK"
     gene            1697..2341
                     /gene="uppS"
                     /locus_tag="ACOIAP_001864"
     CDS             1697..2341
                     /gene="uppS"
                     /locus_tag="ACOIAP_001864"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HGZ2638750.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            2465..3289
                     /locus_tag="ACOIAP_001865"
     CDS             2465..3289
                     /locus_tag="ACOIAP_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2638751.1"
                     /translation="MSKGNNNNNSRNKSKKTSHLNRKKRKLNKKKLAVLICFTVLFLF
                     IAFKVTQGVVALVKSMDKGNKTSQQQNVNSEQFDLGNEEENKNKKYTVFIDPGHGGND
                     KGTESKTSHRYEKDLNLQIAKKLANKLSKQKDIQVVVSRTDDTYISLKDRAILANNSS
                     ADVLVSIHLNAEKNGNTATGIETWYRNKATDGSKELAQTVQSTIVSYVKVRDRGIVEN
                     NFEVLRESNMPAILIECGFLTTPSDEQKIINEKYQEQLAEGIVQGVLSYLDSKGNK"
     gene            3601..5148
                     /locus_tag="ACOIAP_001866"
     CDS             3601..5148
                     /locus_tag="ACOIAP_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HGZ2638752.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIGVGVKVLILILL
                     ILFSINVFISHLKIQVYEDKINLGLINNPDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKYYFGKEAIYVKLKSAVFVLIIKLED
                     REQKIPYLVNLIKNKIVILNQIDNFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     IKSKRLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMIAPNKFIPIAEKNGLINNIGRWLIQEVFGTINKWILEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDVIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMNQVKVLSELGCNFIQGYVFFKPLDEINYKRLLTDGSYINLEDTLLDK
                     CMAVEEE"
     gene            5151..5549
                     /locus_tag="ACOIAP_001867"
     CDS             5151..5549
                     /locus_tag="ACOIAP_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGZ2638753.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDNPIDAKMILKNEEIPTLTLYRL
                     LRKLCANNILTFNKEDGKKYMLNVSLDTISLRTIVEAIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            5589..7322
                     /locus_tag="ACOIAP_001868"
     CDS             5589..7322
                     /locus_tag="ACOIAP_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGZ2638754.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     SHILNYCIYGADIDEKAISILKDSLINKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKKTYID
                     VFKIKNEDICINKFEILEELLKSSKFEHFNINQRLLSDEWILVNKEDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYVVDKSEY
                     RLIYSNDIDNENTNKKILDEIIGIYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLGIFSYEYLVGILNSSIYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYDEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            7554..8765
                     /locus_tag="ACOIAP_001869"
     CDS             7554..8765
                     /locus_tag="ACOIAP_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HGZ2638755.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDVSLRTVMESIIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRKLASNFEIRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            8957..9217
                     /locus_tag="ACOIAP_001870"
     CDS             8957..9217
                     /locus_tag="ACOIAP_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HGZ2638756.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            9570..11282
                     /gene="ptsP"
                     /locus_tag="ACOIAP_001871"
     CDS             9570..11282
                     /gene="ptsP"
                     /locus_tag="ACOIAP_001871"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGZ2638757.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLEN
                     AVAVSKDELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTENVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDKETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEVQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLNMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADEVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(12074..12739)
                     /locus_tag="ACOIAP_001872"
     CDS             complement(12074..12739)
                     /locus_tag="ACOIAP_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638758.1"
                     /translation="MKGKIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKIDNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NGNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDNDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAV
                     NLN"
     gene            13084..14514
                     /locus_tag="ACOIAP_001873"
     CDS             13084..14514
                     /locus_tag="ACOIAP_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HGZ2638759.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDSKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKALKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEEICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            14882..15460
                     /locus_tag="ACOIAP_001874"
     CDS             14882..15460
                     /locus_tag="ACOIAP_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HGZ2638760.1"
                     /translation="MFKRYAEKMTSVLICNNVIDNNESKVYSYGFEILIAFVVNIATM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENLNI
                     DLFKNIIMIIASVSWVGICALCPIEHRSNPISDREKLVYKRIAIFISTVVLLITILSL
                     SLNIFVDYFTYSTFAMFWIFIMLVLGKLKAKI"
     gene            15544..15636
                     /locus_tag="ACOIAP_001875"
                     /pseudo
     CDS             15544..15636
                     /locus_tag="ACOIAP_001875"
                     /inference="COORDINATES: protein motif:HMM:TIGR04223.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
     gene            15936..17315
                     /gene="scfB"
                     /locus_tag="ACOIAP_001876"
     CDS             15936..17315
                     /gene="scfB"
                     /locus_tag="ACOIAP_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HGZ2638761.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVYYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSITPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            17344..17841
                     /locus_tag="ACOIAP_001877"
     CDS             17344..17841
                     /locus_tag="ACOIAP_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HGZ2638762.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKRYIDESYEWYLEAA
                     QNQKY"
     gene            18139..19803
                     /locus_tag="ACOIAP_001878"
     CDS             18139..19803
                     /locus_tag="ACOIAP_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC1 kinase family protein"
                     /protein_id="HGZ2638763.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERIKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIEIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGILRTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKIYSEYNTKKILVMEKVNGTKLSDVEKIKRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLMEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNIEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            19816..22266
                     /gene="recJ"
                     /locus_tag="ACOIAP_001879"
     CDS             19816..22266
                     /gene="recJ"
                     /locus_tag="ACOIAP_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGZ2638764.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKSAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYHVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQNEIPVAFAVINPKQEDCNYPFDSLCGCGVAFKIIQALTPKEEFKTSMYD
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILKEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLSIENGEATGSARS
                     IKGFNIFEALVKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NINVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     NIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRGTFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            22279..22791
                     /locus_tag="ACOIAP_001880"
     CDS             22279..22791
                     /locus_tag="ACOIAP_001880"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGZ2638765.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKGVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            22865..25072
                     /locus_tag="ACOIAP_001881"
     CDS             22865..25072
                     /locus_tag="ACOIAP_001881"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGZ2638766.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            25097..25546
                     /gene="dtd"
                     /locus_tag="ACOIAP_001882"
     CDS             25097..25546
                     /gene="dtd"
                     /locus_tag="ACOIAP_001882"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGZ2638767.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAAKPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            25561..26175
                     /locus_tag="ACOIAP_001883"
     CDS             25561..26175
                     /locus_tag="ACOIAP_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2638768.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHIDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGNFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            26266..27822
                     /locus_tag="ACOIAP_001884"
     CDS             26266..27822
                     /locus_tag="ACOIAP_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HGZ2638769.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFNDFNANNNMESKNLIN
                     RLIYENGVLFSSTVYYENGNLKYESIQNIENMNLEFLDGFDGNKTIEEFLNSLDNESK
                     RNFKKLCKESIKKSMFVVLKQIFNSYVPWGILTGIRPVKIVHNLMDKNLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKIIRETNKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIREFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLDEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            27812..29074
                     /gene="hisS"
                     /locus_tag="ACOIAP_001885"
     CDS             27812..29074
                     /gene="hisS"
                     /locus_tag="ACOIAP_001885"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGZ2638770.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            29148..30935
                     /gene="aspS"
                     /locus_tag="ACOIAP_001886"
     CDS             29148..30935
                     /gene="aspS"
                     /locus_tag="ACOIAP_001886"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGZ2638771.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKESFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEVIFKEVLDVELTLPL
                     PKMTYAEAMSRYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFSEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKASLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGADNIREVIAFPKNQNA
                     VCPMTNAPTLAENEQLEELSIKVDIKDNE"
     gene            31393..32625
                     /locus_tag="ACOIAP_001887"
     CDS             31393..32625
                     /locus_tag="ACOIAP_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HGZ2638772.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYVLMKCFGIKDK"
     gene            32639..33445
                     /locus_tag="ACOIAP_001888"
     CDS             32639..33445
                     /locus_tag="ACOIAP_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="HGZ2638773.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATEYNLESLGGVKTLELIREHNKYIEKSMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFNRKGKIMGEYCKNHLWSLEAVYFKVGENVEVYEADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSNYNI"
     gene            complement(33557..34426)
                     /locus_tag="ACOIAP_001889"
     CDS             complement(33557..34426)
                     /locus_tag="ACOIAP_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2638774.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENTGEVKILSPAAAN
                     VLPPLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            34798..36225
                     /locus_tag="ACOIAP_001890"
     CDS             34798..36225
                     /locus_tag="ACOIAP_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HGZ2638775.1"
                     /translation="MKLTKSIPSMLCLSIVLSLSPVSYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSGSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEELKDISE
                     IAIVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKNFIESKNISKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKKQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNTTAITQVGSGGNENAFKELKDLQVNS
                     NNKRVMYVTNTDKVNIRSDATIEASVIGALNNGDEVEVLEVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(36304..36573)
                     /locus_tag="ACOIAP_001891"
     CDS             complement(36304..36573)
                     /locus_tag="ACOIAP_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638776.1"
                     /translation="MRFEYYYLIQDITGILLAFIGFRMSIIGFRILSIKGISINTLLL
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMFLISIIINPRIKVSK"
     gene            complement(36576..38018)
                     /gene="nhaC"
                     /locus_tag="ACOIAP_001892"
     CDS             complement(36576..38018)
                     /gene="nhaC"
                     /locus_tag="ACOIAP_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGZ2638777.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICVVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLINKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLKFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDNEIEELEIFDTIQKRVD"
     gene            complement(38043..39209)
                     /locus_tag="ACOIAP_001893"
     CDS             complement(38043..39209)
                     /locus_tag="ACOIAP_001893"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGZ2638778.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRIEQEIYGYTTRPDSYNESIVSWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKENDKIMIQEPVYSPFNSVVKNNSRELVISPLQKLEDGNYMMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPIAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEVSYNNGEPWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDKELESKLVQKGKVALNQGNSFGIGGSGYQRINLACPKGMLEEALRRIKNAIN"
     gene            complement(39434..40909)
                     /locus_tag="ACOIAP_001894"
     CDS             complement(39434..40909)
                     /locus_tag="ACOIAP_001894"
                     /inference="COORDINATES: protein motif:HMM:NF025885.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2638779.1"
                     /translation="MLLSIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGD
                     CIKDINFQNILTNKTPFFEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQ
                     AKLRAQLVNSGNISKYTFDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELF
                     AQSIHSASRRKDGPFVAVNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNG
                     TIFLDEIGEMDLNSQSKLLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNM
                     FRRDLYFRLNVLPLKIHPLRERPTDIFEIFGSLKYDIPCNFSLSEEVKEIFKMYRWEG
                     NVRELRNLGEYFCYLGKDIIKICDLPEYILDTIDSNYSRTVCNKVTDNIKKYKFNIGK
                     DKNLMKYDYNFKRSLDEYIFILDNLKKAYDLKERIGRKSLYKIALEENRFLTEQQIRN
                     ILLELQEFGLVNILVGRGGSIITSKGVEFLKNINRSNKLNS"
BASE COUNT        16258 a         4345 c         6966 g        13362 t
ORIGIN      
        1 actggtgtgt atattgaaaa aaatattttc ctgaatgtag ttatagcatc ttattgaaag
       61 gtgtaaattg taatttaaaa tttttagtgt ataataagaa ttgaaaattt aaactgataa
      121 aaattaataa aaaataatta tagattaata atttggggga ggaaatgtat gataaaatta
      181 atagcaacag atttagatgg aactttgtta gatgaaaaga gcgaaataaa tccagagttt
      241 tataaagtat ttaaaaaatt aagagagaga ggaataatgt tttctgctgc tagtggcagg
      301 cagtatcaaa atcttataaa aaaatttgaa gctataaaag atgatatgat gtttatctca
      361 gaaaatggaa cattggtagt atataaagga aaagagatat tatcaaatcc tttggataaa
      421 gaattagtaa atgaaattat agagacaaca agaagcatag aaggtaagaa aatcgtaatg
      481 agtggtaaaa aatacgctta tatagaaagt aaagatgaag cctttataga tgaagttagt
      541 acttactatg caaagtttaa agttgtagat gacttgacta aggtagaagg tgatatatta
      601 aagatagcca tatttgactt taaaggagca gagcataata atagcatcta ctttgaaaag
      661 ttttctgata gagctcaagt atgtatttct ggagtagaat ggcttgattt aactgcaaaa
      721 ggtgcaaata aaggaagtgc tataaaaaaa gtacaaaaaa tgttagatat aaaatatgaa
      781 gaaactatgg tatttggcga ccaattaaat gatgttgaaa tgatgaaaag tgcttatcat
      841 agttatgcca tggaaaatgc aaatgagtat ttgaaagaaa ttgctagatt cagagcaaaa
      901 agaaatactg agaatggcgt tgtagataag ataaaagagg tcatgaaaat aggatagtca
      961 tatgtatgga tgaaaagatt attttgagaa actaaaaaaa tatcaatgta attttgataa
     1021 ataaatttat ttatgtgaaa attacattga tatttaataa acatcaataa gaatcaataa
     1081 gagatattta tttttttatt atactcagta tcttgttttc tatttgaggt gcattttcag
     1141 cagaaattaa ataaacatat ctacctgcct tctcaattat agtattattt gctatttcag
     1201 aattgatttt ttctccatgt ccttctccaa aaggtgcttg tatcatatct tttttataat
     1261 tttctagagt tttatagatt ttatctacct cgtcagtttt tatgacaata atatcttcta
     1321 gagataattt ttcagaagaa ttaattacaa aaccttgaat gatgtattcc tccacatcat
     1381 taaaatagtt aaagtccttt gcatcaaaga tttttgattc ttttataagt aaatcagaag
     1441 attttaatgc ttttttaatt tttgatgtag aaacgttttt ataatcacca cttgaagaac
     1501 aactaaccat tcctaatgat aagattatcg aaaaaaacaa tattaaaatt tttttcatga
     1561 taaacctcca agttttttaa actctgtctt aaattagttt actacataat tatataaaaa
     1621 taaatgtatt taatgttaca gttttgatta ataatgtaat attttgataa taatacctat
     1681 taagaggtga ttagaaatga gaataccaaa acatgtagga attataccag atggaaacag
     1741 aagatgggca agtcaaaatg gtatgacaaa agataaagga tatgaaagtg gaatagaccc
     1801 tggactagag tcttatagat tatgtagaga tttgggctgt gaagaggtaa ctttttatgg
     1861 atttacaact gataatacaa gacgtccgtc agtgcagaca aaagctttta caaaagcatg
     1921 tattgatgct gcaaatatat taatagatga aggtgcagct ttactagttg ttggaaatac
     1981 aaaatctcca atgtttccag aagaattatt accatatact aatagaatta aagctaaaga
     2041 aggtcaaata aaagcaaatc ttctggtaaa ttacgggtgg tattgggact taaataatat
     2101 atcaggagta gaaaatgtaa ataaaaataa tatacaggat tacatacagt catttgatgt
     2161 atccagacta gacttgataa tcagatgggg gggaagacgg agattaagtg gtttccttcc
     2221 tgtgcaatca atttatgcag acttttatgt tatagataat tattggccag attttaagag
     2281 tgacgatata aaggatgcat ttagttggta tgatacacaa gatgtcactt taggtggata
     2341 attaaaaata ttctgattta aggttgtaga gtgttttaaa ttattgaaaa aaaaacttct
     2401 tgatggtaaa ataacactaa taatatgtaa aagtgtaaaa atttatacca agaagggtga
     2461 agaaatgtca aaaggcaata ataacaataa ttcaagaaac aaatctaaaa agaccagtca
     2521 tctgaataga aaaaagcgaa aattaaataa gaaaaagtta gcagtgttga tttgctttac
     2581 agttttattt ttatttattg catttaaggt tactcaaggt gtagtagctt tggtaaaaag
     2641 tatggataaa ggtaataaaa ctagccaaca acaaaatgtt aactcagaac aatttgacct
     2701 tggtaatgaa gaggaaaata aaaataaaaa atatactgta tttatagatc caggtcatgg
     2761 tggcaatgat aaaggaactg aaagcaagac tagtcataga tatgaaaaag acctaaatct
     2821 acagattgca aaaaaattag caaataaatt atctaaacaa aaggatattc aagtggtagt
     2881 atctagaact gatgatacat atatatcatt aaaggataga gctatcttag caaataatag
     2941 ttctgctgat gtgcttgttt ctattcattt aaatgcagag aaaaatggga atacagcaac
     3001 aggtatagaa acttggtata ggaataaagc tacagacggt tcaaaagaac ttgcacagac
     3061 agtacaaagt actatagtat cctatgttaa agttagagat aggggaatag ttgaaaataa
     3121 ctttgaagta cttagagaat caaacatgcc tgctatattg atagagtgtg gatttttaac
     3181 aacaccttca gatgaacaaa aaataataaa tgaaaaatat caagaacaac ttgcagaagg
     3241 aattgttcaa ggtgtgcttt catacttaga ttctaaaggg aataagtaag ttaactttat
     3301 tttaatttga ggataaattt aaaaatttaa tgtgtagatt gtattaactt tatttcgtaa
     3361 tgttggaaac gttgtttgaa tttagaaact atgaaattag aaattatttt atctaatcta
     3421 atttcatagt tttttttgta aaaaattaat aattataaaa atttaaaaaa ataaatttag
     3481 catagtgtaa tgtggttatt tatatgcgat tttaacttgc attgatttgc tatcaattgt
     3541 gctttataat taatatataa agtttaactg taagataatt taaaaaatag gggaatttat
     3601 atgaataaaa atagtatgac aaaaatttac agtttaaata aaataatttt tattataatt
     3661 ggaattttag gaatagtttt acttacaaga catattggag taggtgttaa ggttttaatt
     3721 ttaattttat taatcttatt tagtataaat gtatttattt cacatcttaa aattcaggtg
     3781 tatgaggata aaattaattt aggactaata aataatccag acaagtttat aaatattact
     3841 aaagatgaga acttcctaaa acatgttcaa aactatatca ttagtaatga aaaagaaaac
     3901 tgtgtaatgg cttgttttga tttatgtaga ctcaaactta taaatgatat atatggttat
     3961 gagctagggg atgaagtatt aaataatatt ttaagtaact taaaatatta ttttggaaaa
     4021 gaagctattt atgtaaagtt aaaaagtgct gtttttgtat taataataaa acttgaagat
     4081 agggaacaga agattcctta tttagtaaat cttattaaga ataaaattgt gatactaaat
     4141 cagattgata attttaaaat ggatataaat attgaggctt ctattggaat ctataaattt
     4201 aataataatg aaattgatat aaaaaaagct atagataatg ctgatatggc aaggattaaa
     4261 tcaaaacgac taaagcacat agagtatgta gagtttgata atgctatgga agaagaaata
     4321 caatcaatta tgaaaataga gcgagattta ttcttagcta ttaaaaataa agagtttgta
     4381 attcactatc aacctaaagt tgattcaagt acaggtaaca ttataggttc agaagcgtta
     4441 ataagatggt tgcatccatc attaggtatg attgcaccaa ataagtttat acctatagct
     4501 gaaaaaaatg gtctgataaa caatattggt agatggctaa ttcaggaagt ttttggtacc
     4561 attaacaagt ggattttaga aggtataaat gtcttaccag tttcaataaa tctttccaga
     4621 gtagaattat ataaaaatga tttagttgat ttttttaaac taatgtttaa tacatataat
     4681 attcccaaag aacttataga attagaaatt acagaaacaa cagcactaag agatgtaaaa
     4741 tttataagtg aaaggcttta tgagattaaa tctttaggga tgaatatatc attagatgat
     4801 tttggagtgg gcaattcaaa ttttatcaat cttaagggga taccactaga tgttataaaa
     4861 attgataggt cacttatact ggatatagtt acaaatacaa aaacaaagtt tatggtgaag
     4921 gcaattgtta acctttcaca tgatttaaat gtaaccgtta tatgtgaagg ggtagaggat
     4981 atgaatcagg ttaaagtttt aagtgaacta ggatgtaatt tcatacaagg ttatgtattt
     5041 tttaaacctt tagatgagat taattataag agacttctta ctgacggaag ttatataaat
     5101 ctggaagata ctcttttaga taaatgcatg gcagttgagg aggagtaagg atgatttcag
     5161 aagatgtaga ttattcaata agaatcataa gagctatatt taataatgga gaagataatc
     5221 cgatagatgc taaaatgata ttaaaaaatg aagaaatacc aacactaaca ctatacagat
     5281 tgcttagaaa actttgtgcg aataatatac ttacttttaa taaagaagat ggtaagaaat
     5341 acatgttaaa tgtatcattg gatacaataa gcttaagaac tattgtagaa gcaattgatg
     5401 ggaaaatata tataaacaaa tgtacgagat atgtatctaa ttgcagtaat tgtttaaaag
     5461 gttgtaaagt aaatcgcgaa ttgttagaaa tagaaaaaga aatttataaa cttttatcga
     5521 gaaaatctat aagacaaata ctagaataaa aaattttcag ctatgataat aattggaggt
     5581 tttcggttat ggatgatata tctcaagata attttctact gtctaaagag tatgagaata
     5641 gcttagatgt agatactaaa aaagcaagtg gaatatatta tactcctaaa atcattgtag
     5701 attatattgt aaaaaaaact ttaaaaaatc acgatataat taaaaatcca tatccacgaa
     5761 tacttgatat ttcctgtggg tgtggaaatt ttcttttaga agtatatgat attttatatg
     5821 acttatttga ggaaaatata tatgaattga aaaagaagta tgatgaaaat tattggactg
     5881 ttgataacat acacagtcat atattaaact attgtatata tggtgctgat attgatgaaa
     5941 aagccataag tatattaaaa gatagcttaa taaataaaaa ggtagtaaat gatttagatg
     6001 aatctgatat aaagattaat ctattttgtt gtgatagtct taaaaagaag tggcgatata
     6061 agtttgatta catagttggt aatccaccat atattggtca taaaaagctt gaaaagaaat
     6121 ataaaaaatt tctcctagaa aaatatagtg aagtttacaa ggataaagct gacttatatt
     6181 tttgttttta taaaaagatt atagatattt taaagcaagg aggaattggt agtgttataa
     6241 ctccaagata tttcttagaa agtctatcag gtaaagattt aagagaatat attaaatcaa
     6301 atgtcaatgt tcaagaaata gtagattttt taggtgcaaa tatatttaaa aatatagggg
     6361 tatctagttg tattctaact tttgataaga aaaaaacaaa aaagacatat atagatgtat
     6421 ttaaaatcaa aaatgaggat atatgtataa ataaatttga aatactggaa gaacttctaa
     6481 agagtagcaa attcgaacat tttaatataa atcagagatt actatctgac gagtggatac
     6541 ttgtaaataa agaggatgaa actttttata ataagataca agaaaaatgt aaatacagcc
     6601 tggaagatat agcgataagt tttcaaggaa taattacagg gtgtgataaa gcatttattt
     6661 taagtaaaga tgatgtaaaa ttgaaccttg tagatgataa atttttaaag tgttggataa
     6721 aaagtaagaa tataaataaa tatgtagtag ataaaagtga atataggcta atatactcaa
     6781 atgatataga taatgagaac acaaataaaa agatactaga tgaaattata gggatatata
     6841 aaacaaagtt agaaaacaga agagaatgta aaagtggaat aaggaaatgg tatgaacttc
     6901 aatggggtag agaaaagctt ttcttcgaaa gaaaaaagat aatgtatcct tataaatcaa
     6961 atgaaaatag atttgctata gattatgata acaatttttc aagtgcagat gtatattctt
     7021 tttttataaa agaagagtat ttaggtatat tttcatatga atatctagtt ggaattttaa
     7081 attcaagtat ttatgataaa tactttaaaa taactgctaa aaaaatgagt aaaaatatat
     7141 atgattacta ccctaataag gttatgaaga taaggatttt tagggataat aattatgatg
     7201 agatagagaa tttatcaaag caaataatat caattttatt aaataagtct atagataaag
     7261 gaaaagtaga aaaattgcag ataaaaatgg ataacttgat aatggattct ttaggtatat
     7321 aagcagttgt aagtgtgaaa aaattataat ttgttaattg tttatttaaa ttcacaaata
     7381 aaaagttgac catataaaaa atattaaaaa tatatacttt tcaatatttt tttgataaaa
     7441 taagaatgaa tttgtgcaat tttatttttc tccaataact aaaaatagtt ttttgaatta
     7501 atatttgctg aggaataaaa atcagaaacg tttttgatat agtaggtgat aatatgaaag
     7561 gattagtttt agaaggtgga ggaacaaaag gagcctacca aataggtgca tataaagctt
     7621 taagagagct tggtatagag tttcaaggag taactggcac atcaattggt gctttaaatg
     7681 gagcatatat aattcaaaat gatattgaag taatggaaga tatttggtta aattatgact
     7741 atactcattt tatgaatatt gatagagaaa cctatgagag atttaaaaat gtagatttca
     7801 ctactaaaaa tctcaatgca gtgtttgaac ttataaataa agctagaaaa aatgaaggta
     7861 tagatataag cccattaaga caactaatgg aaacaacatt aaatgaagac ataataagaa
     7921 aatctaaaaa agactttggg cttgttacgg tatggtggga taaaaagatt aatccgtatc
     7981 cattgtatat tgaagatata cctaaaggaa gattgattga ttatttaatt gctagttcca
     8041 gtttgcctat ttttcagacg aatatgatgg atgataagtt gtatcttgat ggaatgtttt
     8101 gtgataacat gccaatagga ctcttggaag ataaaggtta tgaagatgtt gttgtaattc
     8161 ggttgattga tgattttatt gggaaaatga atctaaatcg acatcaaaat ataaatataa
     8221 aaactataat accatcagaa tatctaggag gttctcttaa taaagatagg gataatgtag
     8281 aaaaaaacat tcgactaggt tacttagata ctatgaaagc atatgaaaga tgtactggga
     8341 ttaagtatta ttttgatgta gagtataaat ataatgaaga atattgtttt gataaattta
     8401 gaagtatgag taatgaaaca atacaatata tttgtaattt attgaatata aaaagagatg
     8461 tttcacttag aactgttatg gaaagtataa taccaaagct tggtgaagtt cttggattgc
     8521 caaaggattt ttcgtataaa gatttgtttt actgtatata tgaaaagaaa cttgaagaaa
     8581 ataatataaa caggataaaa ttatatgatt ttaacaaagt tatagatgtt gtaaatacaa
     8641 atattgattc taatagaaag ttagcttcta attttgaaat tagacctaaa attagtatta
     8701 aaaagaacaa aaacacaaaa ttattgacaa attgtattat aaaagacata aaaaatcaaa
     8761 gttaaataaa aaacaaaaaa aaatttgtaa ttatactcga aaaaagtgta tattagtagt
     8821 ataatatttt tgtagcacta gtgggaacaa aaaatgacca taggacaaaa aagtaccact
     8881 tagtaccatt aaagtaaaaa acaggaaaac aattttaaaa aatataaaat gtaaagttta
     8941 taggaggatt taaaaaatgg aaaaagtagt tagtatcaaa aatgcaagtg gattacatgc
     9001 tagaccagca ggaatgtttg ttaagaaggc agctgaattt aaatcaacag tagaggttgt
     9061 agcaaaagac aaaactgtaa atgcaaaatc aataatggga ataatgagtt taggtttagc
     9121 tcaaggagaa gaattaaagt tagttgtaaa tggagaagat gaagaagtag ctttagctgc
     9181 aatggttgaa ttagttgaaa gtggatttgg agaatagata taataatttt ttaaaatttg
     9241 atatttagaa tctaatatta cttaaagtaa agtaacagag aagtattaaa catatacaga
     9301 ccaacatttg tagatattta atttctttgt tactttcatg tttatttaat cagaagatta
     9361 agactattgt taattgggta taaaaataca aatattttac aaaatgaaat aagatatttt
     9421 taatcataaa ttcagaatta aaatacagta acaaatagtt tataaaattt tataaaaaat
     9481 tataagtaag taaaactata aaaatgtaaa ttatttatat aaatttatag catttatgtg
     9541 ctagatgata ttttttagga ggtagggtta tggcttacaa aggaatcggt gcttctcctg
     9601 gtgttgcttt agggaaagcg ttagtagttg aacatagtga attagtaatt gaaaaaaaat
     9661 ctatagataa tgttgaagct gaaattgcta aattagaaaa tgcagttgca gtttctaaag
     9721 atgaattagt aaaagttaag gaaaaggctt ctgaagaatt aggagcagag gaagcagaaa
     9781 tatttgaagc acatttatta gttttagaag acccagaatt aattggttct gcaatagata
     9841 aaatcaaaac tgaaaatgta aatgcagagt atgctttaaa tgaaataaaa gagatgtttg
     9901 ttagcatgtt cgagtctatg gacaatgaat acatgaaaga aagagcggca gatataaaag
     9961 atgttacaaa tagaatactt agacatatat taggaattaa agttgttgat ttgtctgctt
    10021 taagcgaaga agttgtatta atagcacatg atttaactcc atcagacaca gcaactatga
    10081 ataaaaaaat ggttttagga tttttaactg atataggtgg aagaacttct catactgcta
    10141 tcatgtctag aactttagaa atagctgcaa tcgttggatt aaatgatata acttcaaaag
    10201 ttaaggatgg agactttgta gttttcaatg gggacacagg tgaagtaatc gtgaatcctg
    10261 ataaagagac tataaataaa tatactgaat taaaagctaa atatgaagat gagagaaaag
    10321 cattacagct attaaaggga aaaccatctg taactttaga tggtaaacat gtagaattag
    10381 ctggtaacat aggaacacct aatgatatag aaggtctaat aaagaatgat gctgaaggtg
    10441 ttggtcttta tagaacagaa tttttatata tggatagaga ttctttccca acagaagaag
    10501 tacaatatga agcatacaaa gctgtattag aaggaatgga tggaaagcct atagttataa
    10561 gaacattgga tataggtgga gataaagaat taagttattt aaatatggaa cctgaaatga
    10621 atccattctt aggttacaga gcaataagac tttgcctaga tagaaaagat atatttaaga
    10681 ctcaattaag agctttatat agagctagtg ttcatggaag attaagaatc atgttcccaa
    10741 tgatttcatc tttagaagag ttgttacaag ctaaagaagt tgtaaaagaa gttttagcag
    10801 aacttgattc tgaaggtgtg gcttatgcta aagatgtaga aattggtatg atgatagaag
    10861 ttccatctgc tgctgtaata tctgatgtat tggctaaaca tgtagatttc ttctctatag
    10921 gaactaatga cttgattcaa tatacttgtg cagttgatag aatgaatcaa aagataagtt
    10981 atctttataa tcaatttaat ccagctgttt taagacttat aaagactgtt atagacaatg
    11041 cacataaaga aggaaaatgg gcaggtatgt gtggagaatc tgctggagac caaaaaatga
    11101 taccaatact tttaggtatg ggattagacg agttctctat gtctccaata tcaatacttc
    11161 ctgctagaaa gttaataact tcagttaaag agtcagatat gaaaaaatta gctgatgagg
    11221 tacttaatat gggtactgca gaagaaataa aaagctatat agaaaagact tttaatatat
    11281 aattaatgtt atatatttac taaaatttat ttttttaaat aacaaaatta tattttacaa
    11341 attaaaaagg agatgtttca aaataaaagt ttgaagcatc tcttttttat aaaaaattac
    11401 taagaattac ttaatctgtg taatagtcgt tttgtgaaaa aaacaaaaat atattatgat
    11461 tgcagtagat atggatgtta ggagaaataa aagtactatt aaaagtaaga ttcgtcttaa
    11521 aattccatta aaagcagtta agatggagta atataataat cttatgacta taataaaaat
    11581 taaaaaaata tggtattgaa aaataattaa aagtatttaa taatagaatt agggaagaat
    11641 aagtttataa gtaaaaataa ttgattagta gttaataaaa taaatgtgat atccaaataa
    11701 atcctaaatc taatttgagt tttaatatag atagtctaaa gtttgattat taaagattta
    11761 attgtaagtt gttacagttg atgatattga ttagagatta aagtttagaa tagaaagtta
    11821 ccttaaattt aaaaataaaa gataacccaa tctaaaaatt ataatcactc gataggttta
    11881 aggatttatt tgtttattat aaataagagg gtgtctcaaa agcaactttt tagtttatgg
    11941 ggcactctct tttacatgaa attaaatata ttttgttgtt tcaaaaataa aaaagaagct
    12001 tatctctatt ttgagatagc ttctttgtgt actattatta atttaatcag taatataatt
    12061 taaagttata atactagtta agatttactg ctttattagt aaataattct ttaatagcat
    12121 tgtttctgga aactaaatca ttatcagagt tgtttgtttt tttcataatc actgaataac
    12181 gttttttatt tataaaaaat attaaaatct tatcattatc aaaattgtat tctttatatc
    12241 tatcaataga ctcataacct agatttagaa tgtttttatc ttttatacta tctacatcta
    12301 aaatatatga tgggtcagcc tttagtaata tattaattaa acatttttct tcaccagcac
    12361 agaataactc catcttactt gatatagatt tagattgctc tgaagttatt tttgcaggaa
    12421 taaggttgcc attatcatct cttagaagat aaccatgtgt gtcttgttga tatactaaat
    12481 taactttttt cttaggaaca ctaatcattt tatctaaatg tacataatga tgattttcaa
    12541 caaaaccttc attcaatatt tcaacaaagt tatcaatttt acctaggcaa aaagattcta
    12601 tagattcttt acagaattta tttgtaaatg gtattatgtt tacgttttcc tcgtctgtat
    12661 tccatgctat agcataatct aatgaataca cttcttcctc tatatctgca aaattatatt
    12721 gtactatctt tcctttcaaa attactcgac ctccatctta taatatattt aatatacttt
    12781 ataaaactta tattatattt aaataatatc ataaattgga taaatatgat atagtaaata
    12841 agaaaaagtt tgaaaaaaat cactataaat gagtaataaa tataaatagt gtatactaat
    12901 gggatggaaa atgtccacta ttaactttat taccccgcat atataagata aaattattaa
    12961 tataaaaata taatctatca acaatgaata gacttttaaa gaaacttaat ataaaattaa
    13021 ttaaataagt gcttaaaaac gatttacttt aatgatagaa tcatattaaa ggaggataat
    13081 tttatggata taaagaataa aattaaatct atatttttac cagaaaaaaa tgactattta
    13141 gatgatgaag aatttgagta tgatatagaa aataatgagg aagattcaaa ggaagataac
    13201 aaagtacatt taaatgattt aagcagagta aaatatgatt atagagagtt aaaagacata
    13261 gaaaaccaaa cagaagagat gtgtctgcta gcagtaaagc aggatggtac tataattgag
    13321 tttgtaaagg acaagactta taaagtatgt atggaagcag taaaacagac atataaagct
    13381 cttaagtata taacaaatca aaatgaggat atttgtatag aagcagtaaa acagaactac
    13441 agagctttgt actacataaa taataagaca gaaaatgtac taattgaagc tataaaaaat
    13501 gcatcaactt atgatgttat ggaagtattt aaatttgtag aagagcagac agaagatgta
    13561 tgtctagcat ttatagaaag agcatctaaa aatgatgtcg cagagatact aaaaggaata
    13621 aaagagcaaa ctccagctat atgtttagaa gctgtaaaaa aagacggaaa atctttagct
    13681 tatgtaaagg aacaaagtaa tagtatatgt ttagaagctg taaaagaaaa ctacagtgca
    13741 ctgtcttgtg taaaagagca aacagaagaa atatgtatag aagcagtaaa acagaatgac
    13801 tttgcattgt attatgtaaa tgaacagaca gaaaaaatat gtatggaagc agtaaaaaga
    13861 agttatatgg ctctacagta tgtaaataag caaacagaag agatttgttt ggaagcagta
    13921 agaattgatg gaagagcatt acagtacgta aaagagcaaa cagaagaaat ttgcttggag
    13981 tcagttagac aaaatggaaa agtactgcaa tatgtaaaaa aacagactga aaatatatgt
    14041 atagaagcag taagaggttc atttgaagaa cttgaaataa aagaaatatt aagttatgta
    14101 aagataccaa cagaaagaat atttgtagaa gcagtaaagc aaaatggaaa aattcttaaa
    14161 tatgtagaaa atcagacaga attaatatgt ttagaggcag taagagaaaa ctataatgct
    14221 ttagcttatg taaaggaaca aacagaagag atttgtttag aagcagttaa tcaaagttat
    14281 gaagcgctta aatatgtgaa agaacaaaca gaagaagttt gtctaaaagc agtaaaacaa
    14341 gattatagaa tgttgaaata tgtaaataat caaaccgaaa aaatatgttt agaagcagta
    14401 aagcaaaatt atagagcttt agaatttgtt gataatcaaa cagaaaaagt ttgccttgaa
    14461 gcagtaaaac agaatagaaa ggcactacag tatgtaaaac aaaaacaaag ttaaaaggtt
    14521 aaaatatata taaaatatat gcaaacaaat aaaaattaat attttgtaat aaataaagtg
    14581 ggtatctcaa aataagcttt ttagtttgtg aggtactctt tttgtatgaa ataaaatata
    14641 tttttagtct tttaacaatg aaaaagaggg ttatctctat tttgatatat tctttttatg
    14701 catataaagc ttaataaaat tgttttatta taattgtttt attatacaaa taataataat
    14761 aaaattatat aggtcttttt ttgaccagtt ttacattttt aacaactagt tttgtaaagt
    14821 atattgaatt ttctcaaaaa agaatgtact ctatatatgt aaaatttttt tggaggtaaa
    14881 aatgtttaaa agatatgctg aaaaaatgac atctgtttta atttgtaata atgtgataga
    14941 taataatgaa tctaaagtct attcttatgg atttgaaata ttaatagctt tcgtagttaa
    15001 tatagccacc atgctgttta taggtttttt atttggtaaa tttacatatg tattgttttt
    15061 tttaatgtgt tattgtccaa taaggcaatt ttcaggtggt tatcatgcag acaattattt
    15121 tagatgctta ttaaccttta tttttataat tttatctaca atcttaatta tagaaaatct
    15181 aaatatagac ttatttaaaa atattattat gattattgca agtgttagtt gggttggaat
    15241 ttgtgcccta tgcccaatag aacatagaag caaccctata agtgatagag aaaagttggt
    15301 ttataagaga attgctatat ttatatctac agtagtgtta ttgataacaa ttttaagtct
    15361 ttctctgaat atatttgtag attatttcac atatagcaca tttgccatgt tttggatttt
    15421 tattatgtta gtattaggta agttaaaagc taaaatataa gtaaaatatg tatgagggag
    15481 aattaagtta tgaaaaagtt tattgtaaga tttatgaaat ttgctagctg attagcactt
    15541 agcactgcta ttttgtcagc taatagtacc tgtccttgga ttattcatca acctaaagta
    15601 cccaaagaaa tcagcaattt aaagaagaaa aattaaatac aagcaattat ttatacaaaa
    15661 ttattaaaaa aaattattat attttgataa gattaaaaca agataaaatc agatacaaaa
    15721 tttattttat ttattttata ggagcctaat acctatttga taatatatta gtgcgccaat
    15781 ttagggggat atagtgtatt caatgaaatg acttacggtg agtaagtcat ttttgtattg
    15841 tatgtatttt gggtaaactt atgatataat gaagggtaaa gtttaattaa aataataaaa
    15901 aactttagta tagatagtaa tttaggaggt aaggtatgag tatgatacat aaattttcta
    15961 tgaatggata taatatcgtt ttggatgtga atggtggagc tgttcatgtg ttagatgatg
    16021 ttgcatacga tttgttagat ttttataaag aaaaaagtaa agaagaaata ttagaaatat
    16081 taaaatcaaa atatcaagaa gaaaaaataa atgaagcgta tgaagaaata ttaaatttgg
    16141 aaaaagaagg tcttttatat acagaagata catatcaata tcatccaagt tttgtacata
    16201 gagaacctgt agtaaaagct ttatgtttaa atgtagctca cgattgtaat ttaaaatgta
    16261 aatactgttt tgcagctcaa ggtgattttg gaggagaaaa agagcttatg agttttgaag
    16321 ttggtaaggc agcaattgac tatttaattg ctaattcagg aagtagaaag aacttagaga
    16381 tagatttctt tggtggagag cctttaatga attttgaagt tgtaaaacaa ctggtttatt
    16441 atggaagaag tgtagaaaaa gattataata aaaatataag atttacaata actacaaatg
    16501 gtgtattgtt aaatgatgag attatagatt atataaatga aaatatgcac aatgtagtct
    16561 taagtttaga tggaagaaaa gaagttaatg ataacatgag accaacttta aatgataaag
    16621 gaagttatga tattacatta ccacgattta aaaaacttgt ggaaaaaaga gcaaaagata
    16681 agtattacta tataagaggt acttttacaa gagataattt agatttttca aaagatgtta
    16741 tgcattttgc agatttagga tttaaattaa cctctgtaga gccagtcgtt ggagatgaga
    16801 gcaatccata tgcacttaga gaagaagatt tacctaagat atttgaagaa tacgaaaaat
    16861 ttgctgtaga gtatgcagat agacaattac aaggagatgg atttaaattt ttccatttta
    16921 tgatagattt aaatcaaggt ccatgtgtaa taaagagaat aactggatgt ggggctggga
    16981 atgagtatct ttctataact ccaaatggag atatctatcc atgtcatcaa tttgttggaa
    17041 atgaagaatt taaaatggca aatatatttg atgaagaaat tgtacttcca gaaaatttaa
    17101 aaaatatgtt tagagaagcg catgtatata ctaaagaaga gtgtaagcaa tgttggaata
    17161 agttttactg ttcaggtgga tgtcatgcaa atgcgataaa ctttaataat gatatatcaa
    17221 agccatatga attgggatgt gaaatgcaaa gaaagcgtac agagtgctct ataatgatac
    17281 aagctaagtt gatgttagaa ggagcaacca actaaattta tattttaaag gagttgttta
    17341 tatatgatta gagattattt agaagataag cctttaattg atgaaagtgt atttgtggca
    17401 aaatcagcag atgtaattgg aaatgttaaa ataggcaaag attcaagtat atggtacaat
    17461 gcggtagtta gaggtgatga aggcccaata actattggag aaaatactaa tatacaagac
    17521 tgttctatag tgcatggaga tacagaaact ataattggta acaatgtaac agttgggcat
    17581 aggtcaatag ttcatggttg taaaattagt gataatgtat taattggtat gggttcaata
    17641 atattggata atgctgaaat aggagaatat actctgatag gagcaggtac gctaattaca
    17701 tctaataaga agtttccacc aggtgttttg ataatgggct ctcctggtaa agttgttaga
    17761 gagcttacag aagaagataa aagatatatt gatgaatctt atgagtggta tttagaggca
    17821 gcacaaaatc aaaaatatta gtttaaagag tggttgtttc aaaacatatt taaatctgtt
    17881 ttgaggcaac cactaattta ttttattaga ttttgttgat attttagttt ttaaaaagta
    17941 tttgtttaaa tcagatataa aatgtcaaaa ataaaaatca actgagttaa ataattttaa
    18001 taaaattgct agtatatgtg ataaaattaa atattaaaga gtatataaga tattagaata
    18061 tcaattggtg aaataatgtc atatacgata aattaaggtg taagtttttg ggtataccta
    18121 tcttaggagt gaaaagattt gagaataagt tatagaaatt taaagcgata tagagaaatc
    18181 ggatatgttt taataaagta tggttttagt tttattgtag aaagactaaa tatagaaggt
    18241 attgcctata aaataccact atttgaccca ccagaagaaa taaaaaatat gacaactggt
    18301 gagagaatta aaagagtttt agaagaacta ggacctacat atataaaaat aggacagata
    18361 ttgagtacaa gaaaagactt gttagaccaa gatataattg atgaaatatc aaaactcaga
    18421 gatgatgtag agaaatttga ctcaaatata gctattgaga tatttaaaga agaagtgggt
    18481 ttaagtatag aagaaatatt cttagaattt aaagaagaac caatagcagc tgcttcgatt
    18541 ggtcaagttt atgaaggtat acttagaaca ggagaagaag taattgtaaa aattcaaaga
    18601 ccaaatatag aaaaaataat aaaatctgat ttagagattc ttagaactat tgcaaatact
    18661 ttaaaggatt taaaaaaaga ttttaattta gatttagtac aaatgattga agaatttcaa
    18721 actcaattaa tgagagaact tgattacaca tttgaagcta taaatgcaac taaattctct
    18781 aggatattta aaaatagcga tgaagtatat atacctaaaa tatactcaga atataatact
    18841 aagaaaattt tagtaatgga gaaagttaat gggacaaagt taagtgatgt agaaaaaata
    18901 aagagactag gttataacac aaaaactatt gttgaaatag gagttaggtc attttttaca
    18961 caggtattat ctcatggatt ttttcatgca gacccacatc caggtaatat attcgtagtt
    19021 gctaaaaaca agatagcata tatagatttt ggaatgattg gaattattga taataaaact
    19081 ttaaaccaat taaatgaaat tgcattagca ggtgtagaaa agaatgttga taagataata
    19141 tatctattga tggaaatgga tgcattaaat ggagaggctg atattaaggg acttagacag
    19201 gatttacttt atctaataca ttattactat gatatttcta tagaaaaaat aaatgtaaca
    19261 gatatattaa atgaactatt tagatttttt agacagtaca aaatagtcat gcctgcacaa
    19321 tttgtaactc ttgccaagac agtcataaca ttagaaggaa caagtagaac tttaaataca
    19381 gatttttctt ttggctctat gggaaaagag tttatgaaac atcattataa gagtaaattt
    19441 aaccctaaaa atgttgtttt aagttcaaga caaaatatag aagaaatatt gctggacata
    19501 aaaactattc caaagcaatt aaaagcaatt ttaaaaaata tagaaagaaa taacataaaa
    19561 atgcaaatcg aagatgttaa aatgacaaga ttagaaaatt gtataataga gttaacatct
    19621 caaatatctt tgagtttagt gttggcatcc attatagtag gttcttctct tataattgca
    19681 tctccaaata tagaaaataa tatatggata aagtttactg cgatagcagg tttctttata
    19741 tcctttataa taggtctttg tttagttata agaagtatta ggtcaaaata caaaaaagat
    19801 tagggggaat taaatttgaa aaaatggata ttgaaatata aaggtaagat agaggaaagt
    19861 gaatttagca aaaaacttaa tatttccccg gaaatctgcc aaattttaaa aaatagaggg
    19921 atatgtactg aaaaagattc agaaatattt atgaatccat ctttagatta tttaagagac
    19981 ccttttttaa tgaaagacat gcaaaaagct gttgatagaa taaagtcagc agttgagaag
    20041 aacgaaaaaa tttggattta tggagattat gatgttgatg gtgtatcatc tacatctatc
    20101 ttgtgcttat attttaagag tataggttac catgttgatt actatattcc taatagatta
    20161 gaagaaggat atggtataaa tgaagatgct attaagctta taagctctag gggatgtgac
    20221 ttgattataa gtgttgactg tggaattaca tcagtgtctg aggtcaatac agcaaatgat
    20281 ttgggcatag atgttataat tacagaccat catgaatgtc aaaatgaaat tccagtagcc
    20341 tttgcagtaa taaatccaaa acaagaagat tgcaattatc catttgattc actatgtgga
    20401 tgtggtgtag catttaaaat aattcaagcc ttgactccaa aagaagaatt taaaactagt
    20461 atgtatgatt atttagaaat agtaacacta gcaactattt gtgatattgt tccacttata
    20521 gatgaaaata gaataattgt aaaaaatggt ttaaaatcaa tgaaagaagg taaaaatatt
    20581 ggattaaggg agcttataaa agtctgtggc gtagaaagtg acaagatagg ttcttctcat
    20641 ataggttttg caataggtcc taggataaat gcctcaggtc gattggggta ttcttactta
    20701 ggagtagagc tatttactac tcaatcacag gaagaggcag tagaaatagc tagtatattg
    20761 aaagaaaaaa ataatgaaag acagatgata gaagctaaga tgtatcatga agctgaagaa
    20821 atgctaaagt ctaatagcag atacaatgat gacaaagtgt tggttttagc taaagaaggt
    20881 tggcaacatg gaataatagg aattgtagca tcaaagttaa ctgaaaaata ctacaagcca
    20941 acaattcttc taagtataga aaatggagaa gctactggtt cagcaaggtc aataaaagga
    21001 tttaatatat ttgaagctct cgtaaagtgc aaagatttga tgactaagtt tggtggtcat
    21061 gaacaagcag caggattatc tttggattca gataatgtag agattttagc aaatgaaata
    21121 aataaatttg cagattataa tttaactgaa gatgatatga tagagaatat aaatgttgag
    21181 tttgaattac aagaaaatgt aataaattta aatcttgtag aagaattaca taagttagaa
    21241 ccttttggat taaataatcc taatcctaga tttatagtta gaaattacat tttaaaagat
    21301 ttgaaagtta taggtaagaa tcaacaacat ctgaaattaa acatagaaaa agagaaaagc
    21361 tatgaatgta taggatttaa tatgagccat ttaaaatcaa tgtataaagt aggagacaaa
    21421 gtggatgtat tgtttcaatt agatgaaaat aactatatgg gaaataggaa agtacaattt
    21481 ttacttaaag atattcgatt ggctcgacct aaaagtgcaa gtaatgacaa actttcattg
    21541 aaattaatgt caaaaataat accaaaagat actcaaagct tgtataatat atctgtatct
    21601 gattttgaat tatttgatgg aaatacagat ataaatatat ttgattattt tgaaaaagat
    21661 acactaataa tatctaattc tataaatgga ttttatagag caatgtcaga tatatcactt
    21721 atagatttgg attttaacat aaattacaat attattgaag atgttagcaa aaatactgat
    21781 aaattagagc ttatattttc tcctaatatt gataaaatag acttaaaaag atataataat
    21841 attattcttt atgattattt atacaataaa ggcgaatatt cgtatatata tgagaataaa
    21901 agagaagaaa gtgaaattat aaaatattat aataaaacag acctattata tttaaagaat
    21961 gtagttagta atatagttcc atcaagagat gaatttataa caatttataa acaagcactc
    22021 ataaaaaaag aaattgattt ggatatggta aatataaggg gaacttttaa tgtaattcca
    22081 ttaaagtttt ttacgatatt aaatgtgttt agagaattaa atttacttga ctttaattta
    22141 aattatgaaa aaaattctgt actcataaga atattgccaa aaccacagaa aaaattagac
    22201 ttaaatgaga gtttaatact caataatcta aaaaatttag aaaaacaata caatagcagt
    22261 tattaggagg cgtttcccat ggatttaaaa aactttataa ggaatattga tgatttccca
    22321 aagccaggta tagattttaa agatgtgaca actctattta aagatggaga tgcatttaaa
    22381 tatgcagtag attctatagt tgaagaattg aaagataaag gtgtagattt agtaatagga
    22441 ccagaagcaa gaggattttt gatgggtaca cctgtagcat atgctttagg agtaggattt
    22501 gttccaatta gaaaacctgg aaagttacca ggtgaagttg agagttatga gtatggatta
    22561 gagtatggta cagatacttt agagatacat aaggatgcaa ttaaaaaggg tcaaaaagta
    22621 gcaatagtag acgatttatt ggctactggt ggaactatgg aagctgctgc taagcttgta
    22681 gaaaaattag gtggagaagt agtttctatg cagtttttga ttgagctaaa attcttaaac
    22741 gggagagaaa aattgtctaa ctatgatgtt aattctctta taaaatacta gtacttttat
    22801 aatagttggt ataacaccaa ctattttcat atatattaaa attttataca aaataggtgg
    22861 ttatatgcat gataaagaat tacaagaaat aattgaaaaa ataaaagttt atgcacctaa
    22921 tgcaaatttt gaaatggttg aaaaagccta taatcttgca aaaaaagcgc atgaaggaca
    22981 atatagaaaa tctggggaac catactttat tcatccatta gcagttgcaa atattttaat
    23041 agagatggaa ttagatattg aaactataac agcaggttta cttcatgatg ttgtagaaga
    23101 tacagaatat acctatgaag acataaaaaa agaatttggc aaagaagtag cggatttagt
    23161 tgatggagta acgaaacttg gtcaaataaa atatcgttca aaagaagaaa ctcaatctga
    23221 aaatttaaga aaaatgtttt tggcaatggc aaaggatata agggttatac ttataaagct
    23281 tgctgataga ttgcacaaca tgagaacatt aaaatacatg cctccagaaa aagcaaaata
    23341 taaagcaaaa gagacgcttg aaatttatgg aggtatagct catagattag ggatttccaa
    23401 gataaaatgg gaactagaag acagagcatt aaggtttatg gacccagaag ggtattatga
    23461 tttagttagt agagtatcaa tgaagagaag tcaaagagaa gattatattc aaggaattgt
    23521 tgaacttctt aaagataagt ttaaagattt aagcatacca tgtgatgtat atggtagacc
    23581 aaagcatttt tacagtatat atagaaagat gcaaaaaaaa cataagactt ttgaagaaat
    23641 ttttgattta acggcagtaa ggatattggt tgataatgta aaggattgtt atgcagtact
    23701 tggtatagtt catacattat ggagacctat tccaggaaga tttaaagatt atatagcaat
    23761 gccaaaacca aatatgtatc aatcattaca cactactgtt gtaggtcctg atggagaacc
    23821 tttagagata caaataagaa ctcatgagat gcataatata gctgaaaatg gtatagcagc
    23881 ccattggaaa tataaagaag gtatctctag caaagaatca aaagttgaag aaaaactcca
    23941 atggttgaga cagatgatgg agtgggaaaa agatttaaaa gacccacaag aatttatgga
    24001 tgcacttaaa gaagatgtat ttaatagtca agtttatgta tttacgccaa aaggagacgt
    24061 aattgaatta ccagcagaat caacacctat agattttgcc tatagagttc atacaaatgt
    24121 aggtaataaa tgtgtaggag ctaaaattga tggaagaata gttcctattg attataagct
    24181 tcaaaatggt aatattgtcg aggtgcttac atcatctaat tctaatggac caagtagaga
    24241 ttggctcaat atagtgaaga cgccaaatgc aaagagtaga attagacaat ttttcaaaaa
    24301 ggaaagaaga gaagaaaatg ttgaccgtgg gaatacaata ttagaaagag aatttaagaa
    24361 gcatgatata ccgcaaaaag accctcttgt cgaaaaatat atggcattag ttgctaagaa
    24421 attcaatcag ccaagtgttg aagatttaat tgccactgta ggttatggtg gtataatgtc
    24481 atcacaagtt gtatctaaag taaaagacct gtatttaaaa gaggttaaaa aagctaaaaa
    24541 agaacaacag atacaagaag aagatttaaa taaacacaat ataagtgaaa cagaatacag
    24601 taaaaagaga aagaaaaacg catcacaagg aattatagta aaagggcttg acaatatctt
    24661 agtaagattt gctaagtgtt gtaatcctct cccaggagat gaaattgtag gatatattac
    24721 taaaggtagg ggagtggcca tacacagagc tgattgccca aatgcaaaca ataatggcga
    24781 tttcttccaa aatagattgg tggaggtttc atggagttca gcaggaaagg gtaagtttga
    24841 agcagaaatt caaataaaag ctattgacag aagaggaatt gttaatgaga taactcatat
    24901 tgttgcaatg gataaactta gtttaaatgg aataaatgca agaaaaggta aggatagtat
    24961 tgtaagtata aacttacttg tagaagttaa tgacacagag gaattaaaaa ttctaatgaa
    25021 aaaattaaaa gcaattcctg gtgtagaaag tatttataga atgacaaatt agagttaaaa
    25081 taatagggag gaagctatga gagcagtagt acaaagagta tcttcatcta aagttacagt
    25141 agatgaaaac actataggtc aaataaataa ggggttacta gtattattag gagtgactca
    25201 tgatgataaa tcaagtgatg tagattatat gattgacaaa atattgaatc tgagaatttt
    25261 tgaagatgaa aatgacaaga tgaatttatc tctaatggat ataggtggag agcttttagt
    25321 agtatctcaa tttactttat atggagattg cagaaaagga agaagacctg gatttagtaa
    25381 tgcagctaaa ccagaacttg caaataacct ttatgaagaa tttgtaaaaa aagcaaaaga
    25441 taaaggtgtg acagttggta caggtcaatt tgcagctcat atgatggtag agttaactaa
    25501 cgatggtcca gtaacaatac tattagactc aagtaaatct ttttaagggg gaaaacttta
    25561 atgattataa aaaaatttgt agatagttac tttggagtaa atacttatgt attaggtgat
    25621 gaaaagacta aaaaatgtgc agttatagac ccaggtggaa gtttagtaga gacattaagt
    25681 tttgtaaaag aaaatgaatt aaatattgaa tatataatcc ttactcatgg gcatggagac
    25741 catataggat atgttaagga tattaaagaa aaaactggtg ctaaggtagt tgcacatatt
    25801 gatgaaaaag aattattaaa tgacaaaaat aaaaatctaa gttatacaat gagatgtgga
    25861 gcacaagaat ttgatgcaga catatatgtg aatgataaag acaagcttga acttggtgaa
    25921 ttaaaaatga ctttcttgca tactccagga catactcaag gatgtatgtg tataagagtt
    25981 gaagatgaaa tgttcacagg agatactttg tttgctggaa gtattggtag aactgatttg
    26041 tatagtggaa actttaatca aatggaaaaa tcacttaaaa aattatgtaa atatgaagat
    26101 gctgttagag tatatcctgg acatggacca actagtactc taggggttga aaagaagaca
    26161 aatccttaca tgtaatttta tattagtatt taaaaaagta taaaatattt aataactgta
    26221 ttagtgatgg ggttcttcta ctgttaaata gaaggagtta agttgatgtt gtatgttttt
    26281 ttaaaaggac atgattataa gtatgaagta gcagaactta taaaattgtt taccagtgaa
    26341 tttaagttta acgactttaa tgccaataat aatatggagt caaagaattt aataaataga
    26401 ttgatttatg agaatggtgt attattttca agtactgtat actatgaaaa tggaaactta
    26461 aaatacgaat caatacagaa tatagaaaat atgaatcttg aatttttaga tggatttgat
    26521 gggaataaaa cgattgaaga atttctcaat agcttagata atgaaagtaa gaggaacttt
    26581 aaaaagctgt gtaaagaaag tatcaaaaaa agcatgtttg tagtacttaa acaaatattt
    26641 aattcttatg taccatgggg aattttgact ggtattagac cagtcaaaat tgtccacaat
    26701 ctaatggata aaaatctaga tgataatagc ataagaacca ttctaaaaga taattatttt
    26761 ataatagatg agaaaataga tttagctctt gaaatagcta agagagagcg attatttatg
    26821 tatcctatag ataaaaataa aatttctctt tatgtaagta ttccattttg cccaactaga
    26881 tgtgtatatt gttcatttcc ttcaaactca ttaaagcaat ttggacattt aaaaagagaa
    26941 tatgtttata aattgattga agaaattaag gggtttgcca agattattag ggagactaat
    27001 aaagaagttg aaactctata tattggcggt ggaactccaa ctacacttga tgaggaagaa
    27061 ttggatttgc ttataaattc attgtttaat gaattagatt taagtaaaat tagagaattt
    27121 actgtagaag cgggtagacc tgacaccatt acggaacaaa aactaagagt gttaaaaaaa
    27181 cacaatgtta gtagaattag tataaatcct caaactatga atgatgatac tttagtaaag
    27241 attggaagag aacatagagt atctgattta gtagattgct ttaatatggc tcgtagaatg
    27301 ggatttgata atataaatat ggatataatt ttaggtctta tagatgaaga tttaaatatg
    27361 gtaaagaaca cattggatga gataaaaaaa ctttctcctg aaagtcttac agttcataca
    27421 ttagccataa agagggcatc caacttaaat ataaatatgg atagatataa agaacatcta
    27481 acacagtatg aagaaatggt aaaaatgata gatttatcaa tgaaatatgc aaaagatatg
    27541 ggtttaaatc catattatat gtatagacaa aaacatatgt tgggaaattt agaaaatata
    27601 ggttatgcta aagaaggata tgaatgcatt tacaatatac aaattatgga agaaaaacaa
    27661 agtaactatg cattaggtgc aggtgctata tcgaaatttg tttatgtaga tgaagataga
    27721 attgaaagag tagaaaatgt aaaaaatgtt gaacaataca ttgaaagagt agatgaaatg
    27781 ataaaaagga agaaagaaga ggtatataaa aatgttgact aaagctccta gaggaactaa
    27841 agacataact ccaaaagagg cttataaatg gcgttatgta gaaaataaat ttagagaaat
    27901 atgtgcttta tatggatatg aagaaatggt aacacctata tttgaacata cagaactatt
    27961 caagagaagt gttggagaca ctacagatat agttcaaaaa gaaatgtatt cttttaaaga
    28021 taaaggtgat agagaaatta ctctaaagcc agaaggtaca gctggtgtag taagagcatt
    28081 tatagaaaat aaattatatg cagatactca accaacaaaa ttattttatg ttacaccttg
    28141 ctttagatat gaaagaccac aagctggtag acaaagacaa tttcaccaat ttggaataga
    28201 agcacttgga agcgatactc cttcaatgga tgctgaaata attgcactag ctgttcaatt
    28261 tttcaatgaa gttggattaa atgatttggt agtgagtata aattcagttg gttgtccagt
    28321 ttgcagaaaa gagtataatg ctttattaaa agaatatctt gattcaaaag ctgatatatt
    28381 gtgtgatact tgtaatgaga gaagagaaaa aaatccaatg agggttatag actgtaaaaa
    28441 tcctacatgt aaagaaaata tcaaagatat accatttatt gcagaccatt tgtgtgatga
    28501 ttgtaaatct cactttgata aacttcaaga atacttgaag gaaatgaata taaactttgt
    28561 aattgataaa acaatagtta gaggtttaga ttactataga aaaactgctt ttgaaattat
    28621 atctaatgat ataggagctc aaagtactgt atgtggtgga ggaagatatg atggtcttgt
    28681 tgaacaacta ggaggaccaa aaggtataag tggaattgga tttggactag gaattgaaag
    28741 acttttactt acacttgaag gtaatggaat tgaaatagaa aaccctcaat ctacagatat
    28801 atttatagta actataggtg aagaagcaaa tacaagaagc tttaaattat taaaagactt
    28861 aagacaaaat catataagtg cagataaaga ccatatagag agaagtgtta aagcgcaatt
    28921 taaatattca gataaaataa attcaaaatt tacaatagta attggagatg acgagcttaa
    28981 aaatgacact gcgacattaa aaaatatgaa aacatcagag caaactactg taaaattaag
    29041 tacattagtt gaagaattaa agcaaaagct gtaaaataag aaagtatgat gttttgtgta
    29101 ttagataaat atatagcatt aaaattaaat aaaatggagg tagtatcttg gaaactttaa
    29161 agggtttaaa gagaactcac tactgtggag agttgagaga aaaaaacata aatgaagaag
    29221 ttgtacttat gggatgggta cagaaaaaaa gaaatttagg tggtcttgta tttgttgatt
    29281 taagagatac aagtggatta tgtcaaatag tttttgatac agatgtagat aaagaatctt
    29341 ttgaaaaagc tgaaaaacta ggggcggaat ttgtaatagc tgtaaaagga aaagtatgcg
    29401 aaagacaatc taaaaaccct aatatgccaa ctggtgatat agaaatattt gcaactgagc
    29461 ttagactttt aaacaagtca gaaactccac ctatttatat aaaagatgat gatgatgttt
    29521 ctgaagcact aagattaaaa tatagatact tggacttaag aaaaccatct atgcaaagaa
    29581 acttaaaatt aagacataaa gtaatgaata ttacaagaaa ttacttatca aataatagat
    29641 tttgcgaaat agaaacacca tttttaatag ctccaacacc agaaggagca agagattacc
    29701 ttgtaccaag tagagttaat ccaggaaaat tttatgcatt accacaatca ccacaattat
    29761 ataaacaatt attgatggta agtggtatgg atagatattt ccaaatagtt aaatgcttta
    29821 gagatgaaga cttaagagca gatagacagc cagagtttac gcaaatagac tgtgaaatgt
    29881 cttttgttga gcaagaagat gttatgagta tgattgaagg tttgcttgaa gtaatattta
    29941 aagaagtttt agatgtagaa ttgacacttc cacttcctaa gatgacttat gcagaagcta
    30001 tgtctagata tggttcagat aaaccagata ctagatttgg atatgagtta acagatatat
    30061 ctgatgttgt ttgtaactgt ggatttaaag tgtttgctga tgctacacaa cccggaaaaa
    30121 gtgttagagg tataaacgta aaaggcaaag ctgatgactt tactagaaaa caaatatcat
    30181 cactagaaga acatgctaag acatatagag caaaaggtct tgcttggatg aaagtaggac
    30241 aagaaggagt aacttctcca atagcaaaat tctttagtga agaagaaatg aacgctatac
    30301 ttacaaggat gaatgctgaa gtaggagatt tacttttatt tgtagctgat aaaaactcaa
    30361 tagtatttga tgctttagga caagttagac ttgaagtagc aaatagactt aatctattgg
    30421 ataaaaacgt ctataattta ctatgggtaa ctgagttccc agtttttgaa gaagatgaag
    30481 aaacaggtac attctcagca atgcatcatc catttacatc acctatggat gaggatttag
    30541 ataagttaga agaaggtgat aaagcatctt taagagcgaa agcttatgat attgtcttga
    30601 atggttatga gataggtgga ggaagcgtta gaatatcaaa ttctgatgtt caatcaagaa
    30661 tgtttaaagc acttggtttt acagaggaaa gagctaatga aaaatttggt tatttattag
    30721 aagcatttaa gtatggtact cctcctcatg ctggtctagc ttttggtctt gatagacttg
    30781 ttatgttact tgcaggagct gataatataa gagaggttat tgcattccct aaaaatcaaa
    30841 atgccgtttg ccctatgaca aatgctccta cattggcaga aaatgagcaa ttagaagaat
    30901 taagcataaa agttgatata aaagataatg aataatatat agttgtagaa aataaaatgt
    30961 aaaaagtctg gatataaagt gtatttatat tcagattttt tttattagaa ctattttata
    31021 ttttctctct atatattttc ataaattatc cttgtattct catccaatgt aattaaaaca
    31081 ctatgtttaa aaattttaca taaacttgat tgttttagaa actacttttg taatgagtac
    31141 acaattttaa ttaaagaata tataacaaat ttgaaataaa tctaatatat gactcaatag
    31201 attaaattaa aataataaat ttagactatt tacatattta taacttaaat tatatcaaat
    31261 tgataacaaa ctagatatta tacttttttg tagaatagaa ttacaattat ataaagaaaa
    31321 attctattta tagtgaaaaa aaagtagaaa aaagtagaaa ttattctttt ataaagaaag
    31381 ggagggataa tattgcaaga gagagaagaa ttagttttaa atccagttcc aaaagaggaa
    31441 agagttggat ggttagctcc attatttaat atgcttggtt ctaacatagc tatatctgaa
    31501 ctaatggttg ggggaacttt aattttagga atgactcttt ctaatatgat tattacatca
    31561 attataggaa acttaatatt agttgcaatt attatgatac aaggctatat aggttacaaa
    31621 gaagggctaa atacgtatgt attagctaag ggggcatttg gagagatagg aggaaagtat
    31681 cttatatctc tattacttgg tataactagt tttggatggt ttggtgtaca agcaggggtt
    31741 gcaggattat cagtacaaaa gatattcccg agtgtaaacc taacattagt tacagttata
    31801 cttggattat ttatggttgt ttttgcactg tatggcttta aagctatggc taaattcaat
    31861 tacttagtta taccgccact tatgatatta atggtctggg gagtttttaa agctttttct
    31921 acttatggag ttgaagctat ttataattat actcctcaaa caactatgag tatggttgaa
    31981 ggtcttaata ttgtagtagg tcttgttata gttggtgcaa ttatatcacc tgaccagtta
    32041 agatatacga gaagagtaaa agatatttgg attattagtt ttttaggttt agggattatt
    32101 tccttattcc aacaagttgc agctggtgta atgtctatgg gagcacctac ttgggatata
    32161 acagaagtat tggctaattt aggttttgga tgggtagcat ttgttatttt aatacttgca
    32221 tcttggtcaa caaacgtatc aaatgcttat tctggtggat tagcactaaa aactattttt
    32281 ccaaatgtaa aaagaaatgt tttgacttta gttgcaggtc taataggtac gataatagca
    32341 gctactggta taatatttaa atttcagtca tttttatctt tcttgggaat tgcagttcct
    32401 gcaatagcag gaattatgtg gtgtgagtat tattttatac aaggaagaac ttataagcat
    32461 agagaaggaa taaattggat tgcagtaata agctggttga taggctttgc agcgtcgtat
    32521 tatagttcaa aaataaattt cttaatacct ccaataaatg gaattgtagt gagtatggtt
    32581 atttattatg tattaatgaa atgttttgga atcaaagata aataaaggag gcaattacat
    32641 gggtcgtaag gtgaaaatag gtataattca acaacacagt gtacttggag atgttaaaaa
    32701 aaatatagaa aaagcagtag agatgataga tgacttagga aaacaagggg cagatataat
    32761 ttgtttacca gaactatttg ctacagaata taatttagag tctttaggtg gagttaaaac
    32821 attagaatta ataagagaac ataataagta catagagaaa tcaatgtcag aagctgctaa
    32881 aagaaataat gtatatctga tatctccata tggaacctta gaaaaagggt ctacacacgt
    32941 ttataattca gcagttatat tcaatagaaa aggtaagatt atgggagaat actgcaaaaa
    33001 tcatctatgg tcattagaag cagtatactt taaagtgggg gaaaatgtag aggtatatga
    33061 ggctgatttt ggtagatttg gtgtaatgat atgttatgat gcaggttttc cagaagtatc
    33121 cagagaattg acattaaaag gctctgaaat aatatttata ccatctgcat ggagaataca
    33181 agatgaagat atgtgggatt taaatgtatc tcaaagagct ttagagaata ctgtatatac
    33241 agtaggggta aatttagtaa gtaatgactc aaatttaata ctatttggaa agagtaaaat
    33301 atgcaatcct agaggtactg taataactca attagacacg tatagggaaa aatatgtatt
    33361 atcagagatt gatttagatg aaataaaaaa gtatagggaa gatatcccat atttgaaaga
    33421 cagaaaaagt aactataaca tataattcta tattataata caagttcaat ataaaatgac
    33481 aaagagagga tgtatcaata ttaagattaa atttattata ctttgatata tcctctttaa
    33541 tattatcaac ttcgatttaa atattcttaa aatagttgat aagaaagttt ttgaataaca
    33601 atacagcttt agattcatag ttttcactaa accatgaaag atttaaatat cttttaaatt
    33661 caatatcttt gatatgtaac aacttaatct cagggtcttg agataatccc catgattttc
    33721 cacatataaa tccaactcct tgaagtgatt ttataagagc ataaattgta tatggcgaat
    33781 cagattcaaa tgctattttt ggtttaaaat tagctgattc gcataggata tcaattactt
    33841 ctctataatt ctcacccttc gttataacta taaagttttc atctgaaact tcacttagat
    33901 atacttcatc ctttaatgac aaaggatggt ttattgaaac tcctaatagt atttcttcgc
    33961 atgttaaagt tatgctattt tctgagttta gctttgtaaa tgaagaagat atgtacaaat
    34021 caaaatcact ttttttataa gatgatggca aagtatgtga cacattaaaa gtaatattgg
    34081 gatatagttt tctgaaatta ctcaaaagag gtggtaacac attagccgct gcaggagata
    34141 atatctttac ttctcctgta ttttctaaag aagtgtcttg taactccttt tttgaacttt
    34201 ctaccaaatc taaaatgcta tctactcttt ttagaaacaa tcttccatac tcatttaaaa
    34261 caatgtatct tccttttcta tcaaataact gaactccaag ttccttttct aaggaagaga
    34321 tagttttgct taaagctggt tgtgctatat ttaatttgtg tgatgctttt gttatgtgct
    34381 ccattctagc aacagtttga aaatacttaa gatgcaataa atccatagta taaaatacac
    34441 ctcttttaat atgactttag ttatatcaat tttataatca actccacatt atacattata
    34501 atataaagtt tgtataataa accacaatat attaaaaagt tatttaaatt atcatttata
    34561 ttttgtacat aatctaatta aaaaagtagc tttaatatga ttaactaagg aaacattatt
    34621 acaaagctta attacacaaa aaattcattt gatgagtaaa gtattaatgt caggtaagaa
    34681 taaaagctta ttggagaaga aaaataatat tttataataa tgatattact taaattgttg
    34741 tgttatacta ttttaaatag gaaacattta gatactataa ttttaggggg agtcaagatg
    34801 aaattaacta aatcaatacc atcaatgctg tgcttatcta tagttttgag cttatcacca
    34861 gtatcatatg caaatgaaat aagtagaaca acagttgaga atactttagt aggtcaggat
    34921 agatatcaaa ctgctgttga agtaagcaaa aaaggatgga gtagtgcaaa tgaggctgta
    34981 gttgtaaata gtgaatctat tgtagatgca ttggctgtaa caccgtttgc taaattaaaa
    35041 aatgctccta tattattgac agaaaaaaat aatctaaatt cacaaactga gaaagaatta
    35101 aaaagattag gggttaaaaa agtttatata attggactat ctggttctgt atcaaatgat
    35161 gtgcaaaaac agttggaatc taataattta actactgata gagttggtgg tagtgataga
    35221 tatcaaacag ctttaagtat agctaaaaaa atagaagaat taaaagatat atcagaaata
    35281 gctatagtaa atgggtacac aggtcttgca gacgcagtta gtatagcttc tgtagctgct
    35341 actaatggaa tggttatact tccagtgtct gatgcatctg gtatatctag ttttaaaaat
    35401 tttatagaat ctaagaatat aagtaaatca tacataatag gatctactaa tgctgtatca
    35461 gataaaataa aacaaagttt acctaattca gaaagaatag gtggagcaga tagaaatgaa
    35521 actaatggta aagtaataga aaagttttat acatctaaca aattaaataa tgtatttgta
    35581 gctaaagatg gaatgaaaaa gcaaaatcaa cttatagatg ctttagcagt aggagtactg
    35641 gcatcaaaag aaaattcacc tgtactaatc gtaggagagc aattaagtgc aacacaaaag
    35701 agtgtatttt cgaataaaaa tactaccgct ataactcaag ttggtagtgg tggaaatgaa
    35761 aatgcattta aagaattaaa agatttacag gtaaatagta ataataagag agtaatgtat
    35821 gtaactaata cagataaggt aaatataaga agtgatgcta caatagaagc ttctgttata
    35881 ggagctctaa ataatggtga tgaagtagaa gttttagaag tgttaaaaac tggatgggta
    35941 aaaataaaat acaatgaagg tattggatat gttagtggct cttatttgac aaataataag
    36001 cccgataata gtaatgaaaa tataaaaata aagtatgtaa aagaaaaaga tggtctaaat
    36061 gttaggaaag gaccaagtac agaagatgaa aaaatagggc atctttcata tggaagcaaa
    36121 gtggaaacaa tagaaatgtt tgctactgga tgggtaaaaa taaaatataa tggtggatat
    36181 ggttatgtaa gtaatgatta cttatctgat acaccagtta tttaattata agtaacaata
    36241 aaaaactgct ttaatttgta aagcagtttc ttttttgtaa aattttgagt ctaataatta
    36301 tttctatttt gataccttaa ttctaggatt tattattatg gatattagaa acatacaaac
    36361 actccaaatc cagtgcctaa ttccaaactt agatattaat aaattcagtc ctgctatagt
    36421 aaataagcag tatttaatta caagtaaaag tgtatttata gaaattcctt ttatagaaag
    36481 tatcctaaat ccaataatag acattctaaa tcctataaat gccaataata tacctgtaat
    36541 gtcctgaatt aagtaatagt attcaaatct catatttaat caactctttt ctgaattgtg
    36601 tcaaatattt ctaactcttc aatttcatta tctgtatatg taagcatagt aaaaccagtt
    36661 acaccataaa taaatgaaat tataggagta atccaactta agaaacaata tggaataaat
    36721 tttaatgggc ttacaccaag agtttgagca cagaatacag catttgaatt ccatggtatt
    36781 aatggaccac caagcgtagc tgtatcttct ataattctag atagattctg tggttttaat
    36841 ttaaattctt tgtatattgg agacattaga gttcctacaa atacagaagt aaacatcatt
    36901 gacgaactaa atgcatttgc aaagtagctt actataaaag tagaaccaac caatttagtt
    36961 cttgattttc ctattttatt tataagaggt tgaaggagta cttctaagaa tccagttttt
    37021 tgaagaatac cagcaataac aaagactaca aatactagta aaacggtttc agccatactc
    37081 attattccac cacgatttaa tagtttgtca gcatagacaa atccagtatc tatagtaaat
    37141 cctgatagca tgtaatttaa aacatcacct attttttctc cttcttgaaa tactgctata
    37201 ataagtccca tgatagctga acttagtata gatatgatag gtggcttttg tagcaataaa
    37261 agtaataata aaaatattat tggaatcatt gctactaaac caatatgaaa gtttgaattt
    37321 aatacatctt tgatttgatt tatttgaacg tagtctatag tattatttga atacttaaat
    37381 ccaattactg tatacagaac tacacatatt acatatgcag gtcctgtggt ataaaacata
    37441 tgtttcatat gtgtaattac atctgtctta caaactgccg cagctaagtt tgtagaatct
    37501 gatagaggtg acatcttatc tccaaagaaa gcaccagaaa tgactgcacc agctgttaaa
    37561 ccaaggggaa tacccatact agtaccgata ctcatcattg ctataccaga agttccaaga
    37621 gttccccaag atgtaccagt agcaacagaa gtcagtgaac atacgattag tgttgtaagc
    37681 agaaaatatt taggggttat tattgttagt ccactatata ctactgttgg tattgtacca
    37741 gcagctatcc aagctgctat tagtacacca acagaaagta taattaagtt tgattgaaag
    37801 gcatctttac caacctcaaa tccaaaagct tctatttcat cattagtata accaagcttc
    37861 atagctgcag gaactactat aagccatgaa agtaaaaaca ttgtagttat agaagcatta
    37921 aatacaacta tgccaactga tgttagagct attattgcaa gcattactaa caaggaatat
    37981 ctaaatgaag gtatttttct ttctgtattc attttcatag tgtaaattct ccttaaatat
    38041 ttttagttaa ttgcattttt tattcttcta agagcttctt caagcatgcc ctttggacaa
    38101 gctaggttta ttctttgata cccactgcct ccaatgccaa agctatttcc ttgatttaga
    38161 gcaactttac ctttctgtac aagtttactt tctagttcct tatcacttaa tccaagtgcg
    38221 ctaaagtcta cccataataa ataagtgcct tctggttttc taactttaag ttttggcata
    38281 ttttcattta tgtattttat agcaaaatct atattagatt ctaaatattc taaaaatgat
    38341 tctaaccaag gttcaccatt attatatgaa acttctgttg caactaagct aaaacaatta
    38401 tttctcttta tatcaattct agtaaaggca tcatctaaca atttatagtc tttttcatca
    38461 ggtagtatta catatgatga ttgaagacca gctatattaa aagttttagt tggagccata
    38521 caagtaattg tatttttttc aaattcttta gaaatagatg ctataggaat atgcttatgt
    38581 ttttttaata taatgtcact atgtatttca tcagatatga tttttacatt atgcttaaga
    38641 caaatatctc ctagtttttt taattcatct tttgtccata ctctaccaac tggattatga
    38701 ggattacaaa gtatgaataa ttttacatct ttaattttgt tttctatatc ttcataatcc
    38761 atcatatagt ttccatcttc tagtttttgt aatgggctta taactagttc tctactatta
    38821 ttttttacaa cactattaaa aggactgtaa actggctctt gtatcattat tttatcattt
    38881 tcttttgtga gctcgtttat taaaagactt atagctggta taacacctgg actataaatt
    38941 aaccactcac tttttatttt ccaattatgt cttctatcta accaactcac tatagattca
    39001 ttgtaagaat ctggtcttgt tgtgtaacca taaatttctt gctctattct attttttaag
    39061 gaatcaatta tacaaggtgc agctttaaaa tccatgtcag ctacccacat aggaagtaaa
    39121 tcattagttc catacttttt ttccatctct gaccatttag atgaaaaatt attgcttcta
    39181 tcaacaattt cattaaaatt ataattcatt gtaaatacct ccagtaattt taattttatg
    39241 ttaataatat taagcaaaca acgtgccaag attgataata aaaaatattt attcacaagt
    39301 taatatttaa tattaagtta tttcagcgta tagataagat aataatatta attatattta
    39361 aaactttgtg gaaaaggtta tttctaataa attttcaaat atatgaaaat ccaattaaat
    39421 aggtttaata ggtttaactg tttaacttat tagacctgtt tatatttttt agaaattcaa
    39481 ctccttttga tgttataatt gaaccaccac gaccaacaag tatgtttaca agcccaaatt
    39541 cttgtagttc tagaagtata tttctaatct gttgttccgt caaaaatcta ttttcctcta
    39601 atgctatttt atataagctt tttctgccta ttctttcttt taaatcataa gcctttttta
    39661 aattatccag tataaatatg tattcatcta gtgacctttt aaaattatag tcgtatttca
    39721 taagattttt gtctttacca atgttgaatt tatatttttt tatattatca gttactttat
    39781 tacaaacagt tctgctataa tttgaatcta tagtatccaa tatatactca ggcaaatcac
    39841 atatttttat aatatctttt cccaagtaac agaagtattc tcctaagttt cttaattctc
    39901 ttacatttcc ttcccacctg tacattttaa agatttcttt tacttcttca cttagactaa
    39961 aattacatgg aatatcatat tttaatgaac caaaaatttc aaatatatca gtaggtcttt
    40021 ccctaagtgg atgtatttta aggggaagaa cattcaacct aaagtataaa tctcttctaa
    40081 acatgttttt agatacaagt tcttttaaat ttctattagt agctgcaatt attcttacat
    40141 caatatcaat gacattatta gaaccaatac gtcgtacttg tttttcttgt atgactctaa
    40201 gtaatttaga ttgagaattt aaatccattt ctccaatttc atctaaaaat atagttccat
    40261 tgttggctaa ttcaaataaa ccaatttttc cacctttttt agcaccagta aaagcccctt
    40321 catcatagcc aaataattca ctttgtagaa gattttcttg aaaagtacta caatttactg
    40381 ctacaaaagg accatctttt ctcctagaag cactatgaat ggattgagca aataattctt
    40441 taccagtgcc actttcacca attataagga tagatgaatt tgattgagcc attttgttag
    40501 caattttttt tgtattaata gtttgtatgc tagaacctaa tatgtcatca aatgtatatt
    40561 tactgatatt accagagttt actagctgtg ctcttaattt agcttgcttt ttttctaatt
    40621 gagaaaactt tgtcatcttc agtataaatc catcaaatac atttaattgt atatgtttaa
    40681 tctctaaatt tatatcaata tgatttattt taatcagttt ctcaaaaaat ggagttttat
    40741 tggtcaatat gttttgaaaa ttaatgtctt ttatgcaatc accaacaaat gagtcaatca
    40801 tttcatttgc atttatagat aaaatttttc tagccatatg gttatagaat tgaattatgc
    40861 catcattatt tgtgcatata attccatcat caattataga tagcaacaac tgaacctccc
    40921 atgactaaag t
//
LOCUS       DBGJFK010000031        38230 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.031, whole genome shotgun sequence.
ACCESSION   DBGJFK010000031 DBGJFK010000000
VERSION     DBGJFK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38230
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.031"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            77..151
                     /locus_tag="ACOIAP_001895"
     tRNA            77..151
                     /locus_tag="ACOIAP_001895"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:109..111,aa:Thr,seq:tgt)
     gene            complement(299..976)
                     /gene="srtB"
                     /locus_tag="ACOIAP_001896"
     CDS             complement(299..976)
                     /gene="srtB"
                     /locus_tag="ACOIAP_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HGZ2638780.1"
                     /translation="MKKLYRIIINIILILVILYSGFNIYSKLSKYNHDTKTSSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSLDDKNVIIYGHNMKNKTMFNNLNKFKDADFFRQNNKIKINLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNSESDYQNYINDITSKSLYKSPIKVDINDKIITLSTCTYEFDDARM
                     VIHGRLI"
     gene            1108..1442
                     /gene="rnpB"
                     /locus_tag="ACOIAP_001897"
     ncRNA           1108..1442
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACOIAP_001897"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            1720..4254
                     /locus_tag="ACOIAP_001898"
     CDS             1720..4254
                     /locus_tag="ACOIAP_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HGZ2638781.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSEKRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVSNNVEGNNEQDRLEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKLSDVDSKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEGYGFDKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAYNLIKDDYSELENHEIALKRTRKNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDVEEETKEEVASNNQDIDNFVEDKDITDKEYDSNKEDIIE
                     SENKKSKKKAKLFGFIKKDNEEVEQEEENLNGISSDVILDEPIENNRVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSLNNESKLEKESRNLEDEKVKEEKLE
                     NEKSVVIPINKKENSNKKSKNSSKDKSREHRKDAKNYVSDKEDSLDDEDVVSKKNRLK
                     ETIIAVVIVVIVGVGYFITVGNNKKNDKEDIPKSSTQQQANNKLTEEEKKAQAEKEKK
                     EAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGIYYTVYAGSLKVEKTAKETAKEYEA
                     KGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLEELK
                     ESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            4375..6366
                     /locus_tag="ACOIAP_001899"
     CDS             4375..6366
                     /locus_tag="ACOIAP_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638782.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNKDTGVKYIYSFSDHKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKLYMGGINKDNEKFIFISGKNRFEVN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCDIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLNDIENETVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKILLNLSKNMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEHRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            6356..6676
                     /locus_tag="ACOIAP_001900"
     CDS             6356..6676
                     /locus_tag="ACOIAP_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638783.1"
                     /translation="MSSKYNVWNFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSDLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYIDEDIDSDIKGI
                     LDEI"
     gene            6868..7743
                     /gene="galU"
                     /locus_tag="ACOIAP_001901"
     CDS             6868..7743
                     /gene="galU"
                     /locus_tag="ACOIAP_001901"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGZ2638784.1"
                     /translation="MQMTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIE
                     EAIESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHY
                     IRQKEPKGLGHAIHCAKSFIGDEPFAVLLGDDIVDSEVPCLKQLIDTYNEYKTTVLGV
                     QKIAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFNIL
                     EKQTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENL
                     KDDLMDYMRKKVSEK"
     gene            7767..8780
                     /gene="galE"
                     /locus_tag="ACOIAP_001902"
     CDS             7767..8780
                     /gene="galE"
                     /locus_tag="ACOIAP_001902"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGZ2638785.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNLIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHIVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLATGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            8892..10826
                     /locus_tag="ACOIAP_001903"
     CDS             8892..10826
                     /locus_tag="ACOIAP_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HGZ2638786.1"
                     /translation="MKKSLKQYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKIIDGKTYYFNSDGVMQTGWQEKNGKKYYLGADGLSV
                     TGWQEIDGNKYYFDKTGIMQIGWQQIEGKSYYLDKDGKMLTGAQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTDNLPNETVEEMKLLAPKTVILIGGENAISSKLEQEIKTIFNAETKRIAGQDR
                     YQTATRIAEELGSREEIKTAYIVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAISDSVIARMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDADLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMYNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILGK"
     gene            10981..11844
                     /locus_tag="ACOIAP_001904"
     CDS             10981..11844
                     /locus_tag="ACOIAP_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HGZ2638787.1"
                     /translation="MVSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPII
                     EPVGPWLEKMR"
     gene            complement(12052..12933)
                     /locus_tag="ACOIAP_001905"
     CDS             complement(12052..12933)
                     /locus_tag="ACOIAP_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2638788.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPTKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYF
                     PPAIKNFKSFVIKNAQL"
     gene            13346..14194
                     /locus_tag="ACOIAP_001906"
     CDS             13346..14194
                     /locus_tag="ACOIAP_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGZ2638789.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGTEEDRTEAQREKEKNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTADDLAPIPADKIVSIQVCDVLENPYEKLRDESLHDRLA
                     PGEGFGNTEEFVKIIKEHNILPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14273..16195
                     /locus_tag="ACOIAP_001907"
     CDS             14273..16195
                     /locus_tag="ACOIAP_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGZ2638790.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YIERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKIAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEIHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVLGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPISCLANPILGHEAEFKSAEISKEVLVVGGGVGGML
                     ASWICAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDAVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHDVTVIELREEVGADVISEHRKFLMNDFENYNIHTVTSAKVA
                     KFYDDGVDYLLADGTEHDLKGFDSVVLAMGSRNYDPLSEVIKELVKETYVVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            16277..17140
                     /gene="aroE"
                     /locus_tag="ACOIAP_001908"
     CDS             16277..17140
                     /gene="aroE"
                     /locus_tag="ACOIAP_001908"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGZ2638791.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFEKLDLDYRYLAFDI
                     TVDKVKEALSAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENEVEVKGKKVTIMGAGGAATAIQVQCALDGAREISIFNAKDDF
                     YKRAEQTVENIKKEVPKCIVNLYDLEDTNKLYEEIESSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPRKTKMIEDAESNGCKAIGGLGMLLYQGAESFNLYTGLEM
                     PVKEVNELCFK"
     gene            17342..18559
                     /locus_tag="ACOIAP_001909"
     CDS             17342..18559
                     /locus_tag="ACOIAP_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2638792.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYIFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            18795..20660
                     /locus_tag="ACOIAP_001910"
     CDS             18795..20660
                     /locus_tag="ACOIAP_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HGZ2638793.1"
                     /translation="MENVFKRLQEFDGYDGYKESFEMNYLCIYENIPLREQVELANNL
                     IDGILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLDVENLREVVDTFSKSGEYVFYLSNAIKKIEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEYGYKDTKYQRLLMNYIISIVDLNEYLE
                     KRDLDREKINNLSLLICNYLLSVEFKYIGNKLELVNRFLPIVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKVEFEKEINDILLSEKWKSIYFEALKDASGKTEDMIKMSEIYNVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLDFFEKTFKVDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKVVKEAYEKEKNIILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSITV
                     AGSRFRNREYLEKELEKSKIYYLIREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(20838..22202)
                     /locus_tag="ACOIAP_001911"
     CDS             complement(20838..22202)
                     /locus_tag="ACOIAP_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HGZ2638794.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDISIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEVDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGISVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKEQASKIKDKSDVKIPSKF
                     KIIK"
     gene            complement(22380..23723)
                     /locus_tag="ACOIAP_001912"
     CDS             complement(22380..23723)
                     /locus_tag="ACOIAP_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGZ2638795.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(23796..23897)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24226..24879
                     /locus_tag="ACOIAP_001913"
     CDS             24226..24879
                     /locus_tag="ACOIAP_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGZ2638796.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLAKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            25020..26291
                     /gene="brnQ"
                     /locus_tag="ACOIAP_001914"
     CDS             25020..26291
                     /gene="brnQ"
                     /locus_tag="ACOIAP_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGZ2638797.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAIFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            26493..27680
                     /locus_tag="ACOIAP_001915"
     CDS             26493..27680
                     /locus_tag="ACOIAP_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HGZ2638798.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKVIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINAEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNDYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISKKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSLAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(27910..28287)
                     /locus_tag="ACOIAP_001916"
     CDS             complement(27910..28287)
                     /locus_tag="ACOIAP_001916"
                     /inference="COORDINATES: protein motif:HMM:NF020050.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged-helix domain-containing protein"
                     /protein_id="HGZ2638799.1"
                     /translation="MGNIRELRNCVEYMAYMGSNYLTINDLPQNISSKLNNNHMSSNM
                     SIFNDLSQYDKNICISILKSLHMKPMGRTKLMKFMEYNVTEYEVRNMLEYLTRNGYLI
                     SSKGRKGSSITEKGIKIIKNNII"
     gene            28461..28880
                     /locus_tag="ACOIAP_001917"
     CDS             28461..28880
                     /locus_tag="ACOIAP_001917"
                     /inference="COORDINATES: protein motif:HMM:NF019292.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HGZ2638800.1"
                     /translation="MTLIPSVMFALGVVRVIDHLDGMKAAQKLLSPLLKPLLGLPGFA
                     GLTLIASLQSTDAAASMTKELKDDGYIDEKQKAVFCAFQFSGASAITNFFASGAALFP
                     FIGDVPIFIPLTLILIMKFVGANLLRLYLNKFDKGEA"
     gene            28882..29178
                     /locus_tag="ACOIAP_001918"
     CDS             28882..29178
                     /locus_tag="ACOIAP_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HGZ2638801.1"
                     /translation="MSEVVKKEVQVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVVATAIMTIVISRRGFPLLYTKTKM"
     gene            29573..30763
                     /locus_tag="ACOIAP_001919"
     CDS             29573..30763
                     /locus_tag="ACOIAP_001919"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGZ2638802.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQEDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIIQKPVYYPFEAKVKSNNREVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNKSEDWLNELNEYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMGRLKTT
                     FENL"
     misc_binding    30897..31152
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            31211..32212
                     /gene="asnA"
                     /locus_tag="ACOIAP_001920"
     CDS             31211..32212
                     /gene="asnA"
                     /locus_tag="ACOIAP_001920"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGZ2638803.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEDIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            32316..32705
                     /locus_tag="ACOIAP_001921"
     CDS             32316..32705
                     /locus_tag="ACOIAP_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HGZ2638804.1"
                     /translation="MDFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIADKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDVIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSTIIENVNFSIKDEEE"
     gene            33776..34606
                     /locus_tag="ACOIAP_001922"
     CDS             33776..34606
                     /locus_tag="ACOIAP_001922"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2638805.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVITCPERQFSSKNEEKSHKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRVCDKLGTVFKNRGAKLDKNLYILNSSKPTAVLIESFFCDNKEDYESAKKL
                     GYEGMAKLIVEGILNKGVANNEVKQMYKHTIVYSGDDKVSAEILGLYYKRAKENYLVS
                     DIKDYEPHQTQNLYVIGGETCNKMKEMSNTTGEKFTEIYSDDVWSTMDKAIEFVKEKL
                     "
     gene            34881..36536
                     /locus_tag="ACOIAP_001923"
     CDS             34881..36536
                     /locus_tag="ACOIAP_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6765 family protein"
                     /protein_id="HGZ2638806.1"
                     /translation="MNLDFHYYGTYLAAKVAGYNDTDAKTIAYAAQYVDESDKSMILD
                     DVNFTLPTIQTNLEFKKYYADLASWGYKWDFESLNEIKKVWIPFHFLPGNLNNQYKYN
                     GVKESKCLTTSWKFKDGDDQKFRLMCLPNSETVSAIINDLIYFHSTEEYKLQFIGMRM
                     HVLADTWAHMYFIGKPEWYINDVKEFIAEESKYIEETKWTKAEEYRNNGWHSINFTGT
                     PDIGGYESISYLGHGRMGHIPDYGYLNYRYIPNWSSTDDKVKIEKNNQDNFFKAFCQM
                     VYALKCIKNGNDFNINQYDNLTAQQKTEVSKVIATRKNDQSEAWKKAIQALGYNPLEK
                     FDKNKWKNEFIKSSNKEKTDYYYFNLVAKKHVDYVTDFLEEKRLSLEEMFNGYCKFKN
                     FDDTQFAKNRNRVTKIILRGAYIVDAIQLVYDGKYKTPMHGEPFGGTMVSLDLDTDDY
                     IVKISGSIGLYEGGEPYPNSPTRTIGKITFLTKKGKTITAGHETMFKLYRNFTLEAPA
                     GKQIFALKGSYLIRKLREETSKRYLDCLEIANTKDCSVATSTK"
     gene            37061..>38230
                     /locus_tag="ACOIAP_001924"
     CDS             37061..>38230
                     /locus_tag="ACOIAP_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HGZ2638807.1"
                     /translation="MKCTNKKILILSLSIITILASVGEVNALEVKNNSNLEKQTIKET
                     VVPELVGLKMQEAFPDENFRKCISDILNIKDSGDTVITDEMKKTIESTTILYITTESI
                     KDLTGINYFTGLKELHCSSNELKELDVSKNTKLRNLYCDNNRLEKLDITNNKNLVHYS
                     WGNQKEPEKPSGGGSYTPTPIVTKINSLVGSDRYATSIKISKQCWDNANNVVLINNSS
                     IADALSATPFAKVKNAPILLTQNNSLNQLTENEISRLGAKNIYIIGGFNSIDESIENY
                     LKDKGLNTIRISGNDRYDTSIKLAKELSKENKLSKLVLVNGEKGLADAVSMGAISAKE
                     KMPILLTNQNDDMKEIEELIDNKDISKSYIVGGESLFNKDIEDKLPSVIKISGEDR"
BASE COUNT        15037 a         4138 c         6590 g        12465 t
ORIGIN      
        1 ttattaaaat atatatgtag tttttagagt gttaattcta aaagttagct ttattaattt
       61 ataatagaat aagtgtgctg gtgtggctca acggtagagc agctgacttg taatcagcag
      121 gttgtaggtt cgattcctat caccagctcc agtaaagact atgtttttag catagtcttt
      181 ttttattgtt taatgtgtct tttattttgt actacatatt tttattagcc taatataaat
      241 tattggaaca aaagatgaca cagtttaaaa ttattgtttt aaactgtgcc tgtgagtttt
      301 aaatcaatct accatgaatc accattctgg catcatcaaa ttcataggta catgtagaaa
      361 gtgtaattat tttatcatta atatctactt taataggaga tttatacaat gatttagaag
      421 taatatcgtt tatgtaattt tgataatcag attcactgtt aaaatttgtt tttagataat
      481 cataatcaga ctctacaata taagcagaaa aaacatcata taaaaattct tttccattta
      541 agtttatttt tattttatta ttttgtctaa agaaatcagc atctttaaac ttatttaggt
      601 tgttgaacat agttttattt ttcatattat gtccatatat tatgacattt ttgtcatcaa
      661 gagatttatt tctataatcc ataaatagtg tacctgaaat agaatctttt ttataaaaat
      721 ctttgtcaag atagtaagaa ttatctttag attgtacaac tggatagttt atatttgtat
      781 tctcaacaga aagccaaaat ttaaaatcac tgttaatctt tgataagtcc tcttttttat
      841 attctttttt ttgaagttct gaggatgttt tagtatcatg attgtatttg ctaagttttg
      901 agtatatatt aaatccactg taaagtatta ctaatattag tataatgtta attattattc
      961 tatataactt tttcaatata tcacctcgag ttaaatgtag tttatatacc tatattacac
     1021 tatttttgaa taaatttaaa tttttagtat aatattactt tgacatgtaa aagaatttgt
     1081 gttaacataa ctaagtaaaa taaatattaa gtaagccaga taatcgcatg taattttaca
     1141 tgaggaaagt cggagctcca tagagcaggg tgctaggtaa cgcctagtgg gagcgatcct
     1201 aaggatagtg caacagaaat aaaccgccaa cattgtggta aggatggaaa ggcgaggtaa
     1261 gagctcacca gcagctaggc gactagttgg ctatgtaaac cccacctgga gcaagaccaa
     1321 gataggaata aagagtgctg ctcgtactct ccggtaggta ggtcgcttga gcctattggt
     1381 gacaataggc ctagaaagat gattatctaa tacagaactc cgcttataga cttgcttaat
     1441 tattttgata atcaaaaaca tcagtttaaa ctgatgtttt tttatttgta aatttgtcta
     1501 atctactttt aaaattttga ggaatattgt aatataagtt agtacagata ttaaaaatgg
     1561 tataatataa gatagatata aaaagaaaaa gtaaaatgat gtaaataata tgatatgata
     1621 taagatgtag caaatttagt aaataattat ttaaatatca taatcaaatt agcaactttg
     1681 cacaatgtaa atattacaat aaaataattg atttaaggag tgaaggtttt gagtgaaaat
     1741 aatataataa gaaacactgt tttaaatgtc acagcaagtt ttttaaaaca agagtctaaa
     1801 ataaatgaaa agctagatgg tgttttggaa aagaaatttg aaaaagtaga atttaatgaa
     1861 gcaaaatatg cagagctttt aaaatttaat atattgtttt ataagacatt agcaagaaat
     1921 acagaaccac tgattggcaa atggatagta gataagtaca tacctgaaat agatgaatta
     1981 gaaaaggatt tagaattaac tacagcaaaa tgtagaaagt atgtaaataa ggctatgaaa
     2041 gagggattag actctctaaa agccaatgat ttaaatagtt ttttagctta tgataaaatg
     2101 gaactatcag agaaaagacg acgtttagaa aaggattata aggttttaaa cctatacaaa
     2161 gaccttctca atatatctct tagaaaaata agtttagaaa agaaagaatg tggagattta
     2221 tttcttaaaa atcaagcaga tgctaaaaga gaattaaaaa gagaaatcat attctgtgta
     2281 aacaaaatat tggctagtaa taaagatgta gtgtctaata atgtggaagg aaataatgaa
     2341 caagatagat tagaaataaa agcaactgaa attgaggatt tgcaattagg taaagataat
     2401 tcagaaaatg atatgctatt aaatgaaatt aaaaattcaa aagtaaaaca tgaatcaaaa
     2461 ttaagtgatg tagattcgaa gtttatagat aagctaaata gcttaaataa tgaaagtata
     2521 tctcaaacaa tacacaatga atataagaag ttatgtggat tagaagaact tcattctgtt
     2581 gaaggatatg gttttgacaa agaaattatt aaggattttg cctgtgcaac agttgtatta
     2641 gaatttttaa agagaagaaa tagagacctt atagaaggtg caatgagact gactataatt
     2701 ggagaatttg gtcctgaaaa ttttaaggaa tttgtagact atgtaattaa aaataaaaca
     2761 gaaattagtg aagatacgtg gaataaagca tataacctaa taaaagatga ctatagtgaa
     2821 ttagaaaatc atgaaattgc attaaaaaga actagaaaaa ataaagatat cgatattgaa
     2881 gaatacattt acatgataaa aaatgcagat aaagatattt gctttagaag tagtatttca
     2941 atagaagatg atgttgaaga agagactaaa gaagaagtag ctagtaataa tcaagatata
     3001 gacaattttg tagaagataa agatattaca gataaagagt atgatagcaa taaagaagat
     3061 ataattgaat cggaaaataa aaagagtaaa aagaaggcta aattatttgg atttattaaa
     3121 aaagataatg aagaagttga gcaagaagaa gaaaatttaa atggcatttc ttctgatgta
     3181 attttagatg aaccaattga aaataatcga gtaaaatcag aagaaataga gcaaaatgaa
     3241 ctaaaagaaa taaaacaaga agaaccaagt caacatatag aagaagaacg tagtgtaaaa
     3301 atagaaaaac caataaataa taatttagat gaaaaggtat ctttaaacaa tgaatctaag
     3361 cttgaaaaag aaagtagaaa cttggaagat gaaaaagtaa aagaagaaaa attagaaaat
     3421 gaaaaatcag tagtaatacc tattaataag aaagaaaata gtaataagaa atctaaaaat
     3481 tcttctaagg acaaatctag agaacatagg aaagacgcga aaaattatgt atcagataaa
     3541 gaagactctt tagatgatga agatgttgtt tctaagaaga atagattaaa agaaactatt
     3601 atagcagtag ttatagtagt gattgttggt gtaggatatt ttataacagt aggtaacaat
     3661 aagaaaaatg ataaagagga tattccaaaa tcatcaactc agcaacaagc caacaataaa
     3721 ttaactgagg aagagaaaaa agcacaagct gaaaaagaga aaaaagaagc agaagaaaaa
     3781 gcaaaagctg aaaaagaggc tcaagaaaaa gcacaagctg aaaagaaagc aaaggaaatg
     3841 gaagcatata aagatggtaa aggtatatat tacactgttt atgcaggttc acttaaagtt
     3901 gaaaaaacag caaaagaaac agcaaaagaa tatgaggcta aaggtatttc ttcaacaata
     3961 attcaagaaa atggatacta taaaataaaa ataggtgatt attctcaata tggagaagca
     4021 caagaaaaat gtaatgaact agctaaaaag tctattgata catatatagc tatgtatgat
     4081 aagtactatg attataaatt agaagaatta aaagaatcag ctccttcttt gagtgctgaa
     4141 gaacttaaac aaaaatatga agatttaaga agtgagttaa agaataaatc tggatatcgt
     4201 gaatatgtta aacatttaga taaactttat gaagaaatag ttgaaggtgc ttagagtatt
     4261 ataaaaaagg agaaactatg tctcagaata aaaagtataa aaaaatatta tttattttga
     4321 gacattttgt tcacctttat aaaatactta taattctgtt taggtggtga aggtatgttg
     4381 aaattaggag aaaaaatcat atatgagctt tcagatggat ttgagcttag tggtatcagt
     4441 agatactcaa aagaatataa aaagcttcat ataacaaatc tagggaatat aataatcagc
     4501 aaatcagatg aagttaataa ggatacaggt gtaaaatata tatatagttt ttcagaccat
     4561 aaggaaaaat tagaggcagt tttagaagat tctcaaataa ttgtctatgg aaataacttg
     4621 cctttttaca taaaaagtga aaattcaagt aaaaatgtta cagcaaattt aactatgaaa
     4681 ataactttgg atgaatatga tttaatttgc aaaagccaaa gagagtttat attttatcta
     4741 aaggataata tgactatatt aagtttagat gacaataagc tttatatggg tggaattaat
     4801 aaagataatg agaagtttat atttatcagt gggaaaaata gatttgaagt aaattttgat
     4861 gatatagaaa ggtatatttt agaagataaa agagtgtcct tgaagggata ttttcatatg
     4921 gaaagagagg ggattatagt aaggtctgta tctatattta ataacaatat agatagtgta
     4981 gttccatctg atttaaatga gagagttaaa gataatcaaa aaatagggaa ccttcctaaa
     5041 gattgtgata tagtgttctg caagatatca ggaaatatag atggatttga ttataaaaac
     5101 acaaacatgc ttttagtaaa atatcaagac caattaattt ttataaataa gaaatctaaa
     5161 aagactattg taaagtcagc aaaagataat tgttcaaagt taaatttggg agaagatata
     5221 atcttatatg ataataaaaa tgtatttaac ctacatataa atgataaaaa tagagaaatt
     5281 atgcaaatag atgatttaaa tgatatagaa aatgaaacag tgggatatac attaaaacat
     5341 gctccatttt ttattcaaga agatttcgat agcttgacta ttctaaagtc ttttcaaaaa
     5401 gaaatcatat ctataaaaaa tagtgatata aaagacattg taattaataa agagcttgaa
     5461 aacgaaaatt ctaattttgt agaaacagaa ataaaattta ataatcaaaa aatactttta
     5521 aacttaagta aaaatatggt tcaaaaactt atgcaagatg tatttatata tgcaaagcaa
     5581 cctctactta aagaaaattc tattgaagtg atatataaga attggtctaa agctatgaat
     5641 gatatgataa tatttaattt ctttggaaat atttattata tgaaatctga atttgataag
     5701 attttagaaa aagaattaaa tgatgaaata agaatagaag ttataaattc actttataag
     5761 caaatacaag aacacagaaa caatttagat ttattgtcag catatatgcc aagaatatta
     5821 gaaaatcaag aaatagattt gtttgaaaag tataatacta aacttgatgt acaagtgttt
     5881 aagcagatta aaaatctatt gtctgactta tcatataata taagtagtta tttaaatgaa
     5941 gttgaaaaaa gcttagacaa tatcatcttt gtaatttcag gagaagataa gaagaaatac
     6001 aactatagaa tgttaaaaga aagtgaaagt gcaagtcttg atgtattttt aaaacaagct
     6061 atatcaagat taaatcattt agtagaaaat atgtatcctt attatgtaga tgaaactagt
     6121 agggaaatgt ttaagttatt tgagttattg tggaaaaact atagaaatat tgatgatgat
     6181 agtataaaag aaatattatt cgagagaata acaaatacat atgtatttaa acaattgaca
     6241 ttaaataata gtacaaaaga aagaagaaaa gacataattg aaaaaatata taattctgtt
     6301 gattatggaa ccaataaact agatgaaaat atgtttttca caggaggaat aaaatatgtc
     6361 aagtaaatac aatgtttgga attttaacta tgagttctta ggcttggact caggagatga
     6421 aaaaaataat gaagtttatt atgagattga tttagatgaa attttaaatg aaaactatat
     6481 agatgaagat atagatagtg atttagattc tgatggaaat agtattttag gagaattaat
     6541 atcagagatg gatatagatg aagatgtcag tgttgatatg acatatcaag aactagaagt
     6601 tgacttagaa gatttagatt cttatataga tgaagatata gatagtgata taaaaggcat
     6661 cttagatgaa atttagtacc tgtataagtt ttagataaaa tataaacaat acaatattaa
     6721 cttataaaac taaaggtaga tgaaatttca tctaccttat attatcttat agcattaaat
     6781 attgggataa tatagagttt gaagaaaaag tataaatatg gtatattaat ttggtacaat
     6841 agaaaattta cgaagaaggg tgaaaaaatg cagatgacag ttaaaaaagc gataatacca
     6901 gcagcagggc taggaactag atttttacca gcaacaaaat cacagcccaa agaaatgctt
     6961 cctatagtag ataaaccaac tttacagtat ataatagaag aagctataga atcaggaatt
     7021 gaagaaattc ttataataac aggtagaaat aaaaaatcta tagaagatca ttttgataaa
     7081 tcagttgaat tagagttaga actagagcaa aaaggtaaga cagagatgtt agaaatggta
     7141 agagatatat caaatatggt aaacattcat tatataagac aaaaagagcc aaaaggtctt
     7201 ggacatgcaa ttcactgtgc aaaaagtttt ataggtgatg aaccttttgc tgtattatta
     7261 ggtgatgata tagtagattc agaggttcca tgcttaaaac aattaataga tacttataat
     7321 gagtataaaa caactgtatt aggtgttcaa aagatagcta aagaagatac taataaatat
     7381 ggtatattgg atgtaaaaca tatagaagat agggtatata aagttaaaga tatggttgaa
     7441 aaacctgcaa ttgaagaagc tccatctgat atagctatac ttggaagata tataataact
     7501 cctgcaatat ttaacatatt agagaaacaa acacctggta aaggtggaga aatacaactt
     7561 acagatgcac ttcaaactct tggaaaacaa gaggctattt atgcttataa ctttgaaggt
     7621 agaagatatg atgtgggaga taagattggt tttttagagg caacaataga ctttgctcta
     7681 aagagagaaa atttaaaaga tgatttaatg gactatatga gaaaaaaagt aagtgaaaaa
     7741 taaatattag aaaagaggta attacaatgg cagttttagt agctggagga gcagggtata
     7801 taggaagcca tacagcaata gaacttttag aatcaggtta tgaagttgtt atagttgata
     7861 acttaagtaa tagtaactta atagttgttg atagaatcaa ggaattatca aaaaaaccag
     7921 taaaatttta taatattgat atcagaaata aagatgaaat gcatattgta tttaaagaaa
     7981 ataatattga atcaattata cactttgcag ctttaaaagc agttggcgaa tcagtagaaa
     8041 aaccaattga atattacagc aataatctaa taagtacctt aaatttattt gaattaatga
     8101 gagaatatgg tgttaaaaag tttgtattta gttcttcagc tactgtatat ggagacccac
     8161 acacttgtcc tatattagag gattttccac tttctgtaac caatccatat ggaagaacta
     8221 aacttatgat agagcagatg ttggtagata tatcaaaagc agataagtca ttggatatag
     8281 ctcttttaag atactttaat ccagtgggtg ctcataaaag tggtagaata ggtgaagaac
     8341 caaatggagt tccaagtaat ctaatgcctt atataacaaa aatagcagta ggtaaattga
     8401 aggaattaag tgtttatggt aatgactatc caacacatga tggaactgga gttagagact
     8461 atatacatgt attagattta gctactggtc atgtaaaagc attacaaaaa ttagaagaaa
     8521 atccaggact tgttgtttat aatttaggaa ctggaaaggg atatagtgtt cttgatttag
     8581 taaaagcatt ttctaaagca agtggaaaag aaataccata taagattgta ggaagaaggg
     8641 ctggagatgt agccatgtgt tatgcagatt cttcaaaggc agaaaaagag cttggatgga
     8701 aagctaagta tgaacttgaa gaaatgtgtg aagattcatg gagatggcaa agcatgaatc
     8761 ctaatgggta tgaggaatag aatgtatgct tatatgtata aatgtaacaa atttgtaaat
     8821 ataaggtatt ggtaatttta tgttataatt agacacatgt agtaatgttt ctaaaagagg
     8881 gggaagttgt agtgaaaaaa agtctaaaac agtatttagt actagcactg actttagttt
     8941 tagtatttgc atgtggcgta ccagaatcaa gtgcagccag taaacatgtg attatagtaa
     9001 attcaagaaa gaacactcta ggatattttg taaataataa acttgtaaaa gaatttagag
     9061 ttgcaacagg taaaaaaggg tcagaaacac caacagggaa aacaaaagta gttaacaaga
     9121 taaaaaacag accatattat aaaggtaata tacctggagg aagtccaaga aatccattag
     9181 gagatagatg gatgggatta gcattaaaag gaacttatgg agatacatat ggaatacatg
     9241 gaaataataa tgagagttct ataggaaagc atatttctgg tggatgtata agaatgcaca
     9301 ataaagatgt tagatggtta tttgaccaag ttcctgtagg ttcagatgta attatagatt
     9361 atagtaatga cagttatgta aagatagcag caaaatataa gataaattta aaccaaacag
     9421 gatggaaaac agaaaacggt aaaaagtatt atgtaaaatc agatggaaca taccaaaaga
     9481 atagttggtt aaaagtaaat gggaaaatgt attactttga tgcttcagga gtaatgcaaa
     9541 caggatggaa aacaattaat aacaaaaaat attatttagg aactgacgga gcaagagtat
     9601 ctggatggaa aataatagat ggaaagactt attactttaa ttcagatgga gtaatgcaaa
     9661 caggatggca agaaaagaat ggaaagaaat actatctagg agctgatggt ttatcagtaa
     9721 caggatggca agaaatagat ggtaataagt attactttga caaaacagga ataatgcaga
     9781 taggatggca acaaatagaa ggtaagtctt actatttaga caaagatgga aagatgctaa
     9841 ctggtgctca aaaaatagat ggaaaagatt atacttttaa tgaagatgga actataaatc
     9901 ctacatggga tacaattata ggtgcaaata gatttgatac agctaagaag ataagttcag
     9961 ttggaaactg gaatgctgat agttcagata ctgtaatatt agtaaatggt aatgcaatag
    10021 ctgatggtat aacagcaact cctttggcaa gtagctatga ctcaacaata ctacttacta
    10081 atacagataa tttaccaaat gaaactgttg aagaaatgaa gttattagca cctaaaacag
    10141 taattttgat aggtggagaa aatgcaataa gttctaaatt agagcaagaa ataaaaacta
    10201 ttttcaatgc agaaacaaag agaatagcag gtcaagatag atatcaaact gctacaagaa
    10261 tagctgaaga acttggaagt cgagaagaaa taaaaactgc atatatagtt tctggaaatg
    10321 gggaagcaga tgctttatct gtagcttcta aagctggaga agaaaaacaa cctataatat
    10381 tagtcaataa agatggaatt acagaagaat cttataaatg gctaacagaa agaaaattag
    10441 aaaatgcata ctttataggt gggccaagtg caattagcga ttcagtaata gccagaatga
    10501 atgatataac tactgaagat atttcaggaa atagaatata tggagatagt agagtagata
    10561 ctaatgcaaa agtaatagaa aaattctatg gagatgctga tttacaggct gtattagtta
    10621 gtaaatcaga tgctttagta gatgctttat cagctggacc attagctgta aaattacatt
    10681 caccaatagt tttaatgtat aattcaggat tatcgtcaga gcaacaaaga gtatttgcaa
    10741 ataaaaaagt tgaaactcct tatcaaatag gaggcggagt atcttatata gtaatggata
    10801 aattaatgga tattcttgga aaatagtgaa aatatatact gaaaaataat tgtaattgag
    10861 atgtgaaatt caatcaataa aagcttgatt gttttacatc tcaatttttt agtataaaat
    10921 taagtttaag ttatataaaa atcttggaat atttttaaaa ctcatataaa atgaatatag
    10981 atggtatcat catatgttaa gagggtgagt aagattataa agaaaaaata tataatgttt
    11041 attgatgaaa gtggaagagc tgatataaat catgaagacc catttacatt gacaggagta
    11101 atttttgaat ataaatatgc agtaagtcaa ggcgattatg tatgttcttt gaggaaagaa
    11161 atggacgcat ttaaagaata ttgttttgga actagcaaca taggaataca tttgacagat
    11221 atatcaagaa aatcaagagc ctttgagaag tttgatgatt cacagattaa gttattttat
    11281 gatgagttgc ctttatttct atctagacta gaatgtacta taatatcagt aacagtagat
    11341 aaagctagat taaaaaaata ttatgcacct tcaaaggaac cgtatgttgt ggcttttata
    11401 catgttcttc agaattttta ttcgtttgta aataatgaaa ctgtagaatc tgcacgaata
    11461 gttatagagt caagggatga tgtctcaaac ttaaaagtac aaaaggcgtt ttttgatgta
    11521 tttaataatg gaacaatata cttagatata gatgaagaat taagagataa ggttaaaggt
    11581 tttataattg ccaaaaaaga agatgcagac tatagagaag gtttagaaat agcagatatt
    11641 ttatgtaatc ctcttagcag agcaagaaga gggctaatag aagctaatcc aaagtgtatg
    11701 caatatggag aaaaaaataa aatattcaaa tctgtcagaa ataaaatata taccccaacg
    11761 agtgtgaatg atataagaaa ttggggtttt aaagaagttc ctattataga gcctgttgga
    11821 ccatggcttg aaaaaatgcg ttagatacaa ttgacaagtt ttaaaaaatc tgatataata
    11881 aaaataacat agttattcag gaactgaatc cagttgctgt tgtataacga taattactga
    11941 gactcggata ccgactgtca gttaggaatc tatactttta aaagtataga tttttttatt
    12001 ttataaaaag aataaaagag gatatttaaa aataacctct ttattaataa attatagttg
    12061 cgcgttttta atgacaaagc ttttaaagtt tttaattgca ggagggaaat atctatcttt
    12121 tataaatgcc aagtaaaagt ttctttccca acttgggtga ataatctgaa ttacttttac
    12181 ttttgtaaag ctaagcatat tcatatttgg gactacagca attccgaaat tttttgcaac
    12241 taatccagca attacttggt cttcttccac ttcatagact atgttaggct gttgatttat
    12301 ttttttaaac atatcatcaa ttatatatct aagaccactt ctctgattaa atactatttg
    12361 aggataaggt atggtttctt ttaaatctat agtatccttt gcagctagtg gatgactata
    12421 tggtacaatt agtactaagt cttgtttggc aacaggtata aattcaattc ccttttcttt
    12481 ttcaagtttc gaacaaaatg caatatcata ttttctttct ttaagacctt gaataatgtc
    12541 agtagttaca ccagtatgaa atttaaaatc tattgattta gtaggattag attttaaaaa
    12601 tttatgcact atatctggga taaagtcagt accaagtgtt ctaagaaaag ctaagtctat
    12661 ttgtccttca ccagtaccgg ttatttttaa tgattttaca cttgaatcta aaatttctag
    12721 cgatttttcc acatctttta aaaatatttt tccatactta gtaaggacta tatttctacc
    12781 ttccttttca aataaagcta ctccaagttc attttctagt aaagaaatag catgacttaa
    12841 gcttggttgt gttatagata aattttctgc tgcttttgta tagtgttcta aatgtgctaa
    12901 tgtaacaaaa tagcgtaagt gatataaatt caatttttgt tcatcctttc atagatattt
    12961 ttctttatat atttgtagaa gttgaacttt aagatatttt ttacattttt attatatatg
    13021 attatgtagt aagaataaaa gcttttaaaa aaatttatcg ttttttgtct gaattataag
    13081 ataaagatat ttatacgaca tagtagaaaa atacaagaat tatcttataa ataaaatcta
    13141 taaacaaaat ctatgaatta atagtgaatt atcaatttgt tattagtaaa gtctcatgat
    13201 acaataaatt tataaaatct agataaaaaa aatcaaaaaa tagttttgtt ttttaagtaa
    13261 aataatacta ctagtagaat aaataaaaat ataaaatcaa aaatactatt gtttataaag
    13321 aaaataaagg gggcaaattt aaattatgaa taatcaaaaa aatctcaata ttccaattac
    13381 aattagttct tatacattag ggacagaagt ttcattccgt gatagagttc gtattgcaaa
    13441 agaagctgga tttgatggta ttggattacg tgctgaaaat tatattgatg caaaaaatgc
    13501 aggtgttaca gatgaagaga tgattgcaat tcttaatgaa tatgatatga aagttacaga
    13561 agtagaatat ataactcaat ggggaacaga agaagataga acggaagctc aaagagaaaa
    13621 agagaaaaat gtttatcata tggctcactt atttaatgtt aaacatataa attgtggatt
    13681 attagagatg ataccagaag aacaaattat aactgcattg ggagaattat gtgacagagc
    13741 aggtgaactt attataggtc ttgagtttat gccatatagt ggtgttccag atttggctac
    13801 tgcatggcgt gttgtgaaag gatgtaatcg tgaaaatgcg atgcttatat tggatacttg
    13861 gcactgggct agagcaaagc aaacagcaga cgaccttgca cctattccag cagataagat
    13921 agtatcaatt caagtgtgtg atgttttaga aaatccttat gaaaaactta gggatgaatc
    13981 actgcatgac cgtttggctc caggtgaagg atttggaaat acggaggaat ttgtgaaaat
    14041 aataaaagaa cacaatatat taccaagagt cataggggca gaagtaatat ctgattctct
    14101 aatatctaaa ggattatcta ctgctgctga aactgtattt aatgcaacta aaaaagtttt
    14161 ggataaagca tggtctgaag tatctccaaa ataaacttat acaatataaa aatatacgaa
    14221 gtattataat ataaaacttt taaatataaa acttgaaagg aaggaaaatc ttatgaagat
    14281 tagttctatg tttacaccta taagaattgg ttcaatgaca gttccaaatc gttttgtagt
    14341 tcctcctatg ggaaacaatt ttgcaaacac agatggtact ttaagtgaaa cttctaaggc
    14401 ttattatatt gaacgtgctt taggtggctt tggattaata actatagaat ctagtgttgt
    14461 agacaaaaaa gcaaaaggag gtcctcgtaa gccttgttta tatgatgata gcacaataga
    14521 tagttttaaa aatgtaatag atgcttgtca tgatgcaggt tcgaaggtat ctatacaatt
    14581 acaacacgct ggttctgaag gaaatgaaaa aatagcaggt catccattaa aagctgcttc
    14641 tgcaatacct gcatcaaacg gccgtaatac accattagca ataacaacag aagaaatata
    14701 tgaacttata gaatcttatg gagatgctgc attacgtgca caaaaagctg gtgcagatgc
    14761 tgttgaaatt cattgtgctc atggatatct agttagtagt tttatatcac aaaggacaaa
    14821 taagcgtgta gatgagtttg gtggatgttt tgaaaataga atgagattac ctcgtcttat
    14881 cattgaaaat atacgtaaaa aagtaggcaa ttctctagca atattatgtc gtataaatag
    14941 tactgatgat gtactaggag gaattgatgt acatgatagc tcagtaatag cagcatatct
    15001 agaagattgt ggaatagatg gacttcatgt ttcgcgtagt atacatatac atgatgaata
    15061 tatgtgggct cctacgactt tacatgctgg attcagtgca gaattagtta ctgaaataaa
    15121 aaaagctgtt agtataccgg taataacggt tggacgttat acagagccac agtttgctga
    15181 attaatggtt agacaaggaa gatgtgattt agtagcattt ggtagacaaa gcttagctga
    15241 cccagaaatg cccaataaag ctaaaaatgg aaagctagac gaaatgatac catgtattgc
    15301 atgcttacaa ggatgtgtac caaatatgtt ccaaggtaaa cccatatctt gtcttgcaaa
    15361 tcctatatta ggacatgaag cagagtttaa gtcagccgaa attagtaaag aagttcttgt
    15421 tgttggtgga ggcgttggag gtatgcttgc atcatggata tgtgctaaaa gaggtcacaa
    15481 tgtaacttta gttgaaaaat ctgaagttct tggtgggcaa atgcgtttag ctgcatatcc
    15541 cccaggaaaa ggagatatta ctaacttagt tagaagttat atttcaaaat gtaatcaata
    15601 tggtgtaaaa atatgtacta acacagaagc tacagtagaa cttataaaag agaaatcacc
    15661 tgatgcagtt attatagcta ctggggcaac tccacttgta cttcctatac caggaatcaa
    15721 tgattcagga ttaatacatg ctgtagacct tcttgatggt aaaaaatctt gtggtaaaaa
    15781 agtacttgtt gttggtggtg gaatggttgg atgtgaagtg gcagctttcc ttggagaaca
    15841 agaacatgat gttactgtta ttgagcttag agaagaagtg ggtgcagacg taatttcaga
    15901 acaccgtaaa ttccttatga atgattttga aaattataat atacatactg ttactagtgc
    15961 aaaagttgct aaattttatg atgatggtgt tgactattta cttgcagatg gtacagagca
    16021 tgatttaaaa ggttttgact cagtagtact tgcaatgggt tctcgtaatt acgacccatt
    16081 aagtgaagtt ataaaagaac ttgtaaaaga aacttatgtt gttggtgatg cagtaaaagc
    16141 tcgtagagca ttagatgcaa caaaagaagc ttttgaagta gcattaaata tataaataat
    16201 aaataaattt ttctttgtaa ataactgaat aggttatttg caaagaaaat gataatattg
    16261 ggaggaaatt agagttatgg aaatttcagg tagaacagga ttatttgcat taataggtac
    16321 accagttggt cactctaaat caccagtgat gtataattat agttttgaaa aattagattt
    16381 agattataga tatttagctt ttgatattac agtagacaag gtaaaagagg cactttcagc
    16441 aataaaaact tttaatataa aaggagctaa tgttactatg ccatgtaaat ctgctgttac
    16501 agaatatatg gatgaacttt ctccagcagc tcgtataatt ggagcatgta atacaattgt
    16561 aaatgacaat gggaagttag ttggtcatat aacagatggg gtaggctatg ttcgtaattt
    16621 aaaagaaaac gaggtagaag ttaaaggtaa aaaggttaca attatgggtg ctggtggtgc
    16681 agcgactgct atacaagtac aatgtgcatt agatggagca agagaaatat ctatcttcaa
    16741 tgctaaggat gatttttata aaagagcaga gcaaacagtt gagaatataa aaaaagaagt
    16801 accaaaatgt attgttaatc tatatgattt agaagataca aacaaacttt atgaggagat
    16861 agaatcaagt gatatattga caaatgcaac tcttattggt atgaaacctt atgacaatga
    16921 aacaaatata aaagatacta gtgttttgag aaaggattta gtagtaacag atgttgttta
    16981 taatcctaga aaaacaaaaa tgattgaaga tgctgaatct aatggatgta aggctattgg
    17041 tgggttagga atgttattat accaaggagc agaatctttt aatctatata ctggattaga
    17101 aatgcctgta aaagaggtta atgaattgtg ttttaaatag agataaaagt gattgcttaa
    17161 acaatggaaa aacatatgta tttcaatgtt tttagtaata aatttcaaat tgtcatagtg
    17221 ggttttgcat tatagtctag ttaaatttga agttttaact gactatgctt taaacccatt
    17281 atggggataa gtttattgta cacaaaaatg ttaataaatt aacaaggata ggagaagaac
    17341 tatgaacaat aaaaaatatt atcctactgc catagcgttg tatttttcat attttttact
    17401 tggtattgga atttcaattt taggacaata caaaccagaa ttttcatcaa tgtggggggc
    17461 taaaacacta tcagatggaa cattggatgt aagtattgtt ttagctgtta ttgctgcact
    17521 aggattaggg agacttatat cgtatccatt tgcaggacct atttcagata agtatggaag
    17581 aaaagtaagt ggtcttatag gaaactttct acatgcaatt ttctttgttg gaattgtatt
    17641 ttcaccaaat ttttatatag catatatatt tgcaataatt ggaggggcag caaattcatt
    17701 cttagatacc tgtgtaacgc cttcttgtat ggagatattt gctagtttag gaacaatagc
    17761 aaatatgttt actaaattta caatagcttt agcacagttt ttgcttcctt ttataattgg
    17821 atttgttgca gcaaattcaa tatcatttaa agttattttt atagtaacag cgattcttat
    17881 tgtagtagat gccattttga tagctgtgtt accatttcca ccagctaata atgttattga
    17941 taataaaggc aaaacagtta aatcagagaa gatgaaattt acaccaacaa gtatagctct
    18001 tgtttgtatt ggatttacat gtacatctac atttgtatta tggttaaatt gtaatcagga
    18061 attgggaaaa ttatatggga tggctgaccc tacaaaaatt caatctttct actcaatggg
    18121 agtaatatgt gcagtattaa taacttcttt acttattaaa aaatatatta aaccaataag
    18181 aatattagtt atatatccta taatagcttt acttatgcta ttagttgtat attttgttca
    18241 aactccaact atttgtatgc tagggggatt tgtaataggt tattcagcag caggaggtgt
    18301 tcttcaatta acaacatcaa ctgcaaatga aatgtttcca actaataaag gaaaaataac
    18361 gtctatagtt atgattgcat ctagtatagc aaactatgtt attttaaata tagcaggtat
    18421 tatcacaaaa tcaggtggag ttaatggacc aaaatatgtt gtattattta atgtggcaat
    18481 aacatttgtt ggaattttac ttgcattgtt tgtaaacatg agatatgaaa aagaaaaagt
    18541 gtatgattat gatgtttaat attagtataa tatatttata gagaaatcca aatttaggat
    18601 gggtttctat taaaaataat taaaattaat aaggatatta tttatagtta taagataggg
    18661 tatttacata attaataata aggatattac tagaatttca atttctagta atattttttt
    18721 gcgtataaat gtaaacttgg cgaaataagt agtataatca atataaatta catcatgtaa
    18781 aggaggataa tttggtggag aatgttttta agcgattaca ggaatttgat ggttatgatg
    18841 gatacaaaga atcatttgaa atgaattacc tatgtatata tgaaaatata cctttaagag
    18901 aacaagtaga gcttgcaaat aatctaatag atggaatttt aaatatgtat aaaagtgaat
    18961 ctaatgaaat ttatttattg gaggatagta attctaagtc tttaatttgt tattttgaaa
    19021 tttttatgaa aaagataaat actttggtaa aagaaatgat tattgatgag aaatggttat
    19081 ataaattaac taaagaatta atatataaga gtaaaaaagt tgagtatgta aaactaggat
    19141 tagttttaag tgagaaatat ctagatgtag aaaacttaag agaagttgta gatacatttt
    19201 ctaaatctgg agaatacgta ttttatttga gtaatgctat taaaaaaatt gaattttaca
    19261 atacatattt atttaattta tctaaaaaag ctacaggttc aataaaagta tttgctattg
    19321 ttaatatgga aaatttagat tctaaaataa attcctattt aattgaatat ggttataaag
    19381 atacgaagta ccaacgatta ttgatgaatt atattatttc aattgtagac ttgaatgagt
    19441 atcttgaaaa acgagattta gatagagaaa agataaacaa tttatcactt cttatatgta
    19501 actacttgct aagtgtagaa tttaaataca taggaaataa attagaatta gtgaatcgat
    19561 ttttacctat tgtagtaaat tatgggacta attttgaaag tttatattcg atttttctaa
    19621 tagctataaa cgttttaaaa gatgaaaata tagaatgtaa taaggttgaa tttgaaaaag
    19681 aaataaatga tatcttgctt agtgaaaaat ggaaaagtat atattttgag gcattaaaag
    19741 atgctagtgg aaaaacagaa gatatgataa aaatgtcaga aatttataat gtaaacttat
    19801 cttttgatga cttattacca tatttaaata gagacattag agattttgag gtatattggc
    19861 atatatctaa aaaaggaacg acaagttcta gattaaaatt attggatttt tttgaaaaga
    19921 catttaaagt agatgattta attggaaaaa tgaaagatat agaaaaagat aaattgactc
    19981 aagaatatta tgatgatatg ttatttttta ttgtgcttaa aggaagtaaa tcactatatc
    20041 ctgaaggaaa gaatatatct ttaaaaggaa tatttggaaa tataaatgaa gtaagaaaag
    20101 aatctataaa tattttaaaa agatatagag agaaattatc tcttgaagaa ttaaaagttg
    20161 ttaaggaagc atatgaaaaa gaaaaaaata tcatattgaa ggatgaatta agaagagtat
    20221 tatatgaaag taacaactta aaaaaagaat ttgtaaatat tgaaaaaata aaagtagatg
    20281 aacatggtaa ggatatctat ttaacttcaa taactgttgc tggttcaagg tttagaaata
    20341 gagaatatct tgaaaaagaa ttggagaaga gtaagatata ctatctaatt agagagaaag
    20401 ataatctata tgatgaaaaa gctattaaaa tagttggtga aactggatat gtaataggct
    20461 atgttccaag aaaagaaaat tatattttga gcaatttatt agatggagga aaactattgt
    20521 attgtagagt aactgaatat aatttatatg aagattgtat ttacgcaaat gtgtacttga
    20581 gctataaaga tgtaattgaa acggttgaaa actctttaaa gatggtttta gataagagta
    20641 gaataaaact tataaactaa gacgtctata tactgcttaa atgatgtaat cctgattagt
    20701 taattatttt ttctggaatt atggtgtatt ttatgagcaa tggtaatgaa taggaaataa
    20761 aaaaacaatt gttttgtata tatgatgtgt ataaatatat ttatatattc atatttacaa
    20821 aataattgaa atttatgtta ttttatgatt ttaaatttag atggaatttt aacgtctgat
    20881 ttatctttta ttttagaagc ttgttcctta actttattta ataattcaga ttcatctaca
    20941 actaatactt ttctttcctt catcaaccat ttaccatcac aaatagtaga atctacattt
    21001 tcactagtca tagaataaac tatatttcca attggattat gcattggtaa acaatggatt
    21061 gtatctggat ttaaaataat catatcggct ttttttccta cttcaagact accaatttct
    21121 ttttctaata aagcacattt tgctccattt atagtagcca tttctaagac ttcttcagct
    21181 ggcactactg ttgggtttaa agttctacct ttatgtatta atgatgtaag atacatatcc
    21241 ctcataaggt ccattctatt atttgaagga gctccatcag taccaattga aacagatatt
    21301 cctttttcta acatttcagg aattgatgca aatcctagaa caactttcat agctgaacct
    21361 gggtcatgag aaacttttac atcatgtaat ctaaataagt caacttcctt atgagtaagc
    21421 caaactgtgt gagcggctaa aagatttggt cctaatacac ccagtttatc aagatattca
    21481 actgttccaa ctccattgtt ttgttttaca aatgaaattt catcagctat ttcagcaata
    21541 tgcatatgta tacctgtatt gtatttatca gctaactctt tagttctaac aagtaattct
    21601 tcagttgtat taaaaatagt tcttaatgca aaccatattt taattctctc attagatgtg
    21661 ttattaaact tgtggaataa gtctaattga gtgttgattt cctcatcagt agttttttgc
    21721 catgcctcag gaagaccatc tcctgtatcc ataactgatt tagctaaaca agctctaagt
    21781 ccagttttat caacagcttc aaccatagca tctacatatt gaccaccaga ttctaaaaat
    21841 gtagtgacac cagactttat caattcaaca caacatgcag tagatgaaat caatgaatct
    21901 tcataattga agctactttc gtatggccaa attctttctc taagccaagt taaaagtaca
    21961 acatcatctg caagaccacg tcctaattgt tgagataagt gaacgtgtgt attgactaac
    22021 cctggcatta gtatttttcc tttagcatca tatatctctg catctttatc tacaatacta
    22081 atatcaaact taccaacctc ttttataata ttattttcaa taagtatgct tccgttttca
    22141 tatacctctc tatctgcatt catagtaatt agatatgcat tttttataag taattgtgac
    22201 ataaacacca ctccttttct atgtattttt atatctatgt attatgataa taaattttct
    22261 atacaaagtt aatagcaaaa tcaatttaca tataaagtga ttttgctatt tataaattta
    22321 aaataaataa gattttattc tatataattt aaaatattga cctagaacta tttaaaatat
    22381 taacttagaa ctaagtttac aactgcaagt aaacctataa tccaaagtgt aatactgatt
    22441 ttatcagttt ctttagctac cacatgcatt attatatatg aaataaatcc aaagcataaa
    22501 ccaatactta tactataagt taaaggcatc aataagactg taacaaaagc aggtactgct
    22561 attttactat cagcaaaatc aatctgtttt atgctttcaa acatgaacac accaaccatt
    22621 acaagtgcag gagctgcagc gtaagtagga actataccaa gtaatggtgt aaatataagt
    22681 gtagctaaga ataatgctgc tgttactatt gaagcaagtc ctgttcttgc acctgctgca
    22741 ataccagaag cagactctcc aaatgttgta acagtactag ttcctaagaa tgagcctatt
    22801 aaagtagaag aaacatctgc atacaacatt cttcctaaat cttttatttc accattctca
    22861 tcttcaagac ccatttgttt acaacaagta ataagaaatg ctaatgaatc aaacatgtct
    22921 ataaacatga aagagaatat aggtccaatt aatgagaatt tcaatgcacc tacaatatct
    22981 aatttaaaag caactggtgc tatactagga ggtgttgaga ttattgctgt tggcaactcc
    23041 acaaatccaa atataacaga tattattgtt gcaactacta tacttatcaa tattccacct
    23101 ttaacttttt tatattctag tattgccatt aagataagag caaaaagagc tattaaaact
    23161 gttggtgtaa aatctgcaag tgaaactata gtatctggat tagctattat aacacccata
    23221 ttttttaaac caacaaaagc aaggaaaaga cctatacctg ctgaagatgc tactgccaat
    23281 tctctaggaa ttgcgtctgc aattgtcttt cgaagacctg ttactgcgag tgtaaagaag
    23341 acacatccag atagaaaaac taccccaaga cctgtttgcc atgggattcc tgcccctata
    23401 accaaagagt atgtgaaaaa tgcatttaat cccataccag gagctagagc aaatggtgca
    23461 tttcctaaaa tcgcaaatat aagtgtacca atggctgtag ctagtatggt aactgttata
    23521 agggcggctt tatccattcc agcctcagat aatattgctg gatttacgaa aactatgtat
    23581 gccattgtta agaatgtagt aactccacct attacctctg ttttaaggct agagccacgt
    23641 tcgctgaatt taaacatttt gtctaaaaag cttaatgatg aattatttcc acctggttgt
    23701 acattgttag tgtttggtac catttttacc tccaaaaaac tttaagatat aaacaaaaaa
    23761 atatatattc atatagatag aatagaacat atattcaagg ttgacattct attcatagaa
    23821 aacccattta aggtgagttt gtagaaacta ttagaccgta ttactaatat tatatgaaca
    23881 ttttctattt gtttttctgt tgtattatat cgtaatattg tattatttac aataaatata
    23941 ataaaattat tcgttttttt gtcgatttta taaaaaatta aggttattta ttggcaaaaa
    24001 ttactgtttt aaataattga atatgtatga gtataatgtc aattattcta acttgtttta
    24061 tactattaat ggaagtttat tataaatgag tttgtgatat aattataaaa gtactgaata
    24121 cacggatatt tcgtaaaaac tttttaatat attaaatatg tatattaagt taatatatta
    24181 aaaaaaataa tatcaaaaat aatataattt atagtggagg ggaaaatgac taaaattatt
    24241 aaagtacaaa aacctaaatt tacaggagaa ttagaaatta ttgaaaatct tgaagatata
    24301 cttgaagata tatttaatga tgaaaaaata tttaataaaa ttatagaaaa tgaagttata
    24361 agtgatttag attctgtaag agttagcttt gaatcttgta tatttagaaa tgtatccttt
    24421 gaaaattgca atttaaaaaa gattgattta cttgatgttg tatttgaaaa ctgcaattta
    24481 tcaaatacat tttttgatgg aggaagtata tatagagttg aatttaaaaa tagtaaattg
    24541 ataggtgtta gatttgatga ttgtatactt aaaaacgttt tgttcaagga tgttttagct
    24601 aagtattcta acttttcgtt ctctaaattt aagatagttt ctattttaga ttcaaatttt
    24661 gaaaattctg tatttcaaga agtaaaaggt gacaatctag tatttgagta tacaaactta
    24721 aaaaaagcaa actttaatgg aactaaactt tctggcatag attttactac taataatatt
    24781 gagggaattg agattggtat agatgatatt agaggagcaa tttttgatgt gtcacaagca
    24841 attgatttaa cgaaattgat gggaattatc ataaaatgaa aaaaatattc ataagataaa
    24901 ttgggaaaac gttaacaatg tgtgaatttt taccagattg acatttttct gaaaataaag
    24961 taagattatc ttaatattca aaatattttc aaagggggta atttagtgtg agtaagcaga
    25021 tgagagatat ttttatagtt ggttttgctt tattttctat gttctttggt gcaggaaatc
    25081 ttatgtttcc tccattttta gggatggaat ccggcaaaga ctggttaatt cctcttattg
    25141 gatttgttgt tgcagatgct ggtatagcaa tgcttgttat tatagcaaca gcaagatgta
    25201 agggaagcat ggatgatgta cttaggagag ctggtaaagg gttagcaaga gtaatgagtg
    25261 tagctgctct agcatgttta gcacttcttg taataccaag aacttgcgca acaacatatg
    25321 aaatgggtat tatgcctata tttggagacc atggaccagt agctaaagct atattttcaa
    25381 taattttctt tgggttaact ttagcattta ctattaggtc ttctaaggtt atagacataa
    25441 taggtaagta tttaactcca gcgttattat tagtattatt tgttttaata gtaaagggta
    25501 taatttctcc agcaggacct atgagtcctg aacatatgat agataaaaat ctatttggtg
    25561 aaggtatatc acaaggttat caaacaatgg acgctctagg tgcagcatct atggcaacta
    25621 taatgttgat gtctataata gctaaaggat atacatcaga taaagaccaa ataggaatga
    25681 ctattaaagc tggttttgta gcctgtgtat ttctagcagt agtatatggt ggtcttactt
    25741 atttaggtgc aacagtttca actttatatg acactagtat acctcaagca tctttattag
    25801 ttgaaataac tagtatattg ttatatggtc aagtaggaaa ggtaatttta ggtgtaattg
    25861 tggcacttgc ctgtctgact acttctacag gtttaacagc atcaatatca acttattttg
    25921 aaggaataag taaggcgagt tataaacaac tggttatagg tatatgtgta gctagtatgc
    25981 ttatatcaaa tttaggtgtt gattctataa tagccatatc agttccaatc ctacaaacta
    26041 tatatcctgt tttattagca atagttgtta tggagttggc tggtaaacat ataaagaatg
    26101 ataatgcttt taaaggtgca gcatatgtta cattagtgat tagtttatta tcagctataa
    26161 atggaatgac aggagctgtt ccatttatac aaagcttacc acttgcaggt ttgggcttta
    26221 actgggtaat accagctata ttgggtggaa tagttggtaa ctttataaaa agcaacaaac
    26281 aagtagcata ataatttgta attaatttaa ttttataata tattaatttt tagtactatg
    26341 ggtaggttta atttaaacct aatctaccca tagtactttt tagattggat tagaatagca
    26401 tgtatataat tttttataat ataatttttc tttgaagtat gataaaatta gtaatagtga
    26461 taagaaagta caaatttagg aggttttaat taatgcttag aaaaataaca gcatttatgc
    26521 tatctatatg tttaattatt ggacttacag gttgtagttt acttgtgggc aagaaagata
    26581 aagagaaagt tatagatgat tttaaagttg cagtggtaac tcaaccatta tctgaaaata
    26641 aagtacaata caatatggtg gaagagatgg caaaagaata tgaggaagag aataagattg
    26701 ataaagacaa agatggtcaa actaaagtta aacaaactat aaagcatgtt gtacttccag
    26761 aaaattttac ttctaatata gatagtgcta ttaataagat agtaaagttg gctgacgata
    26821 aagaagttca ggctattgta gtttcaactg accaagcggg gcttttacct gccttacaaa
    26881 aggtaaagga aaagcgtcca gaaataataa ctatttctgc ccctatggga gatgataaaa
    26941 atcaattaag ccaatttgtt gatgtgaatc taggggttag tgcagaggaa agaggaaaag
    27001 tattagctga acgttcaaaa gaaatgggag caaaagcttt tattcattat gcctctacag
    27061 atgatttgaa agatgttaat atagccaaaa gattagaaat gattaaagag acttgcaaaa
    27121 atataggatt gccatttgta caagttaata ctccaaatat aaatgctgaa gaagacaaaa
    27181 acaaagttaa gcagttttta aatgaagata ttgaaaaaca agttaaaaaa tatggaaaag
    27241 atataaatgt atttggtgta aatgattata tggatgaagt tatattgact aaggctttag
    27301 aattaaagta tatagttgca gagcaaagta atccatcacc aatacaaaca tatcctagtg
    27361 ttatgggtct gaaaatatct aaaaaagatg ctcaaaatta tgataaaata aacgacatga
    27421 taagtgaaaa ggctaaggct tttggtatgt caaatagact tggtggatat cctatgccaa
    27481 tggatgcttt tctaccatca ttagcaattt atcttgccac tgaaatggta aaacaagatt
    27541 taacacaaga agatgtatgt gacccagact atttagaggc gtttacagaa ttaagatttg
    27601 ggataggttc agaatttaca cctctaacag aggtacttta taattatcaa tcagtaattt
    27661 taagccaatt aatttattaa tattaaggaa gtgtctcaaa atgaactttt tagtttatga
    27721 ggcactcttt ttgtattaaa taaaatatat ttttatcttt ttaacaatta aaaagaagct
    27781 tatctctatg ttgagatagc ctcgttttta acataaataa gttttattat tttataaaaa
    27841 atttatagaa aaataaaaaa ttataattat atataaattt tgataaagta aagatgaatt
    27901 actataggtt taaattatat tattttttat tatttttatg cctttctcag ttattgatga
    27961 gccttttctt cctttactag aaattaagta tccattgcgt gtcaaatatt ctagcatatt
    28021 tcttacttcg tattctgtga cattatattc cataaatttc attaactttg tcctccccat
    28081 tggtttcatg tgcaatgatt ttaggataga aatgcatatg tttttgtcat attggcttaa
    28141 atcattgaat atggacatat tacttgacat atgattatta tttaattttg aagatatgtt
    28201 ttgaggtaaa tcatttattg taagataatt agagcccatg taagccatat attcaacaca
    28261 atttctcagt tctctaatat ttcccatcca agtgtatgaa tttaaagctt ctaaaagact
    28321 cttatcgagt tttatgtttt tatagggaag ttctttctaa gtaaagactt atttacaaaa
    28381 gtaactttgt taaaagtatt atagctgcaa actttagaga cgatggaggt actggttcta
    28441 gagaaggatg gttatatgca ttgacactaa taccatcagt tatgtttgca cttggagtag
    28501 ttagagttat agaccactta gatggaatga aggcagctca aaagcttctt agtccactat
    28561 taaagccatt attagggtta cctggatttg cagggctaac cttgatagct agtttacagt
    28621 ctacagatgc agctgcatct atgactaaag aacttaaaga tgatggatat atagatgaaa
    28681 aacaaaaagc tgtattctgt gcatttcaat tttcaggcgc ctctgcaatt acaaatttct
    28741 ttgcttctgg agcagcacta tttccattta taggggatgt accaatattt ataccactta
    28801 ctttaatatt aattatgaag tttgttgggg caaacttact tagattatat ttaaataaat
    28861 ttgacaaggg ggaagcttaa catgagtgag gtagtaaaaa aagaagtaca agttaaaaaa
    28921 ggaaatgtga tagatgcgtt tattggagga gctagaaatg gattccaaat aagtaccaat
    28981 tcaatggctc caaatgtcat cttcggtttt gctataattt ctgtattcaa tttaacaggt
    29041 cttttagatg taatagggac tatatttaca cctgtaatga gtatatttgg acttccaggt
    29101 gttgtagcaa cagctataat gacaatagtt atatcgcgga gaggattccc attattatac
    29161 acaaaaacta aaatgtaaaa ctacatatat tggattagga gctgatgcta caccagggtt
    29221 tcataatcca aatgtaacat ttgatacgaa agctttagaa tatggtgtag attggttgaa
    29281 aagagattgg gataatatcc aaattaataa ttctacattt aaaattataa ttatagaagt
    29341 tatagaaaaa gattgcttat gttaattgaa aaataattaa tatgggcaat cttattttgc
    29401 tataatgaaa cttattttga aatattgaaa aaatatggta gaaaaagcaa ttatatttta
    29461 agtctattgg gcaaaaaagt gatattataa tattaaggat tataaaatga tatcaaattg
    29521 aatctagtaa tacactaaca attataaaaa ttttattttt aggagggaaa aaatgagtaa
    29581 gtataacttt gacagagtaa tagatagagt aggaacagat tgtgtaaagt gggattttag
    29641 aactaattgc tcaactaaag cacaagaaga tggtttgcct ttttggattg cagatatgga
    29701 ttttgaatgt gcagaaccaa taatagaagc attacgtaaa aaagttgaac ataaaatatt
    29761 tggatatagt tccaatgata gtgataaata ctttaatgca gtttgtgatt ggtataaaag
    29821 gagatttaac tgggaaataa atagaaaaga tattattttt agccctggtg ttgtacctgc
    29881 tgttgctatt ttagtaagaa tattaactaa ttctaatgaa ggcgtgataa ttcaaaagcc
    29941 agtgtattac ccatttgaag ctaaggtaaa gagtaataat agggaagttg taaacaatcc
    30001 tctaatatat gaaaatggga cttatagaat ggattatgat gatttggaag aaaaagctaa
    30061 gtgtagcaac aataaagtac tgatactttg tagccctcac aatcctgttg gaagagtttg
    30121 gagagaagat gaattaaaaa aggttgtaga aatatgtaaa aaatatgacc tatggataat
    30181 agctgatgag atacattctg atttaattag aaaaggattt aaacatactc ctttacagtc
    30241 attatgccca gagtacaagg ataaaatagt tacatgtata gctccaagta aaacatttaa
    30301 tctagctgga atgcagttgt ctaatataat agtgaataat gatgaactaa aaaagaaata
    30361 tcaagaagag gttacagctg ttggagttgc aacttcacca aatccttttg ctattgtagc
    30421 tacaatagca gcatataata aaagtgaaga ctggcttaat gaattaaatg aatacttaga
    30481 taataatata caatttattg atgaatactt aaaagaaaac ctaccaaaag taaaacttgt
    30541 ttatccagaa ggaacatatc tagcatggtt agattttact gcttatggat tgaatgaagt
    30601 agaacttgag gatttaatgt ttaaaaaagc taatgtatta tttgatgaag gttatatatt
    30661 tggaaaagaa ggaataggat ttgaaagaat aaatgtagct tgtccacagt ctttattaaa
    30721 agaatgtatg ggcagattaa agactacatt tgaaaattta taaagtatag gtaaaaagta
    30781 ataaagtgtt taaaaataaa aaaataataa gcttgacaaa ttttaactaa tcacttatca
    30841 tactattatg aataaataga aaacataaga gagctaaatt ttattgaatt aaactcttaa
    30901 agactttgaa aggaagagta gttatagaat gtaattaaag cgagttggtg atggtgtgag
    30961 accaatatga agtctatagt gaagaacatc ctggagttgc taaccgaaat tttaaaagag
    31021 taggcttagt cggaaccaaa ccgttatcat attggggtgt atcgagtaat atctgtacat
    31081 tgtgagctgg gtttgaattt atttcaaact aatcagggtg gtaccgcgga aaagcaacct
    31141 ttcgtccctt ttatataggg atgaagggtt tttttaatgg aaaaatatat aaatataggg
    31201 agtgaatgat atgagcacaa taataccaaa ggattataaa agtagtttga acgtaattga
    31261 tacacaaata gctataaaaa aattaaaaga tttttttgaa atgagactaa gtaatgaatt
    31321 aaatcttata agagtttcat ctccgttatt tgtattgcca gagacgggtg caaatgataa
    31381 tttaaatgga gaaaaggctg taagctttga tataccattt atgaataaaa atgcagaaat
    31441 tgttcaatca cttgcaaaat ggaaacgatt agctcttaaa aaatatgggt ttgaagttgg
    31501 cagtggttta tatacagata tgaacgcaat aagaaaaaat gaagaattag acaatataca
    31561 ttctctttat gtagaccaat gggattggga attggttata gataaaagta gtagaaatga
    31621 aaagactcta aaagatgttg tgaaaagatt gtatggagta tttaaggata ctgaaatttt
    31681 tgtatgtagt atgtatgaag atataaaaga aatattacca gaagaaataa cttttataac
    31741 atcacaagag ttagaagata tgtatccgga attatcacca aaggaaaggg aagataaaat
    31801 cgtaaaagag aagaaagcag tgtttataac tcaaatagga aaaacattaa tatcaggaga
    31861 aaaacatgat ggaagaagcc ctgattatga tgattgggaa ttaaatggag atatattatt
    31921 ttacaatcct gttttagatt cagcactaga attatcttca atgggaatta gagttgatga
    31981 agaatctctt gatagacaat tgaaacttgc tggatgtgaa gagagaaaag agtttgacta
    32041 tcataagatg cttttaaatg gagagcttcc atatacaatt ggtggaggaa ttggtcagtc
    32101 aagaatatgt atgtatttct tacaaaaagc tcatatagga gaagtacaag ttggagtatg
    32161 gccacaggat atgattcaaa attgtagcag tgcaggaatt gaattattat aatttaaata
    32221 taagctaatt aataaaattt atgtctaata tgttcatcaa attaattata tcggttataa
    32281 tgtagaataa cctataatta taagaggtga taaatatgga ttttctaaaa ataattatta
    32341 atatagtttt agatatttta aaaaaaattt tggtgagatt taaaaatgct aaatttggtt
    32401 tggtttttgt atttgattta cttaaactac ctgattttat gacagataaa agaatcaata
    32461 tagctgataa aataaaagta atttctgtat taatttttac tatatcttac tttgtatctg
    32521 gggttgatat aattccagag atgattgctg gggcatttgg ttttatagat gatgtgatag
    32581 ttttaatttg gagtataggt atagtgaatg aagaaatcaa taagtataga gttattgcaa
    32641 aaaaagataa acattcaact ataattgaaa atgtaaattt ttctataaaa gatgaagaag
    32701 aataataatt tatatgtgta tgctaacata ttatataaca tcatatatta ctagatagta
    32761 gctaaatcct agtttttgct actgtctagt gataaaaatt tgactgacct ccaactgaga
    32821 aacaaaaaat atacgattaa ctaacatcca acgaacataa aactgactat tatttaaata
    32881 agattttgct caaattttca gatatttctt ttttcacttc ttctaaaaca tgagagtatt
    32941 tatttatagc tatttttata tctatatgac ctaatctgtc taaaatagtt tttttattag
    33001 ttccatataa taacatcaaa gttacatttg tatgtctaag ctcatgtaat tttatatatt
    33061 taaagatgtt tttaaaagat ttagactaat atcataagta ttcttaatac attgaataac
    33121 tatgatttta ttatatcaaa tctaagttat aaatactatt tgatgataga gtagttgtat
    33181 acagaaatat atagatgaac ttttgaaaaa gtaataaagt agaggattat ataattaaac
    33241 ataatggata agtagaagga gcagaaccaa tagtatagaa ggttcttttt ttatgcgttt
    33301 agatgatttt taagtcttgt tttatgttaa aataataggt aatacagata taacaatagt
    33361 ttttttagca ataaatatat ttataaaatt ggcaatatta agaatagcat tttatgcttt
    33421 gctagaatgc ttaagagcaa taaaaacaca taaacttaat ggttctcttg taatcaatgg
    33481 aggaaataag aaaagtcgca atgctggttt gtatattttt tctagaatta gttgacatac
    33541 ttataaattt taacttttta tttatgttgc tataagattg ggttgatttc ttatgattaa
    33601 ataatctagg aatatcagaa tttttcttta ttttatttat tttgtataaa aatctaagta
    33661 tattaaaaaa tatgtactta aatggattac cagttattaa agattaaaag agaaaatagg
    33721 tagtttatta gataccatgg cagatgaatc aactattaaa ggaggagaat aaataatgaa
    33781 aatatgtata acagtaggac acagtatttt aaaaagtgga gcatgtactt ctgctgatgg
    33841 agtagttaac gagtaccaat ataacaaatc tcttgcacca gtattagcag atacatttag
    33901 aaaagaaggt cataaggtag atgtgataac atgtcctgaa agacaattta gttctaaaaa
    33961 tgaggaaaaa tctcataaaa tacctagagt taatagtgga ggatatgact tacttataga
    34021 gctacattta aatgcaagca atgggcaagg taaaggttca gaagtactat attatagtaa
    34081 taaaggttta gagtatgcga ctagagtatg tgataaacta ggtacagtat ttaaaaatag
    34141 aggtgctaaa ctagataaaa atttatatat cttaaatagc tctaaaccta cagcagtatt
    34201 aattgaaagt ttcttctgtg ataataaaga agattacgag agtgctaaga aacttggata
    34261 tgaaggaatg gctaagttaa ttgtagaagg tatattaaat aaaggtgttg caaataatga
    34321 ggttaagcaa atgtataaac atacaatagt gtacagtggt gatgataaag tgtcagcaga
    34381 gattttagga ttatattata agagggcaaa agaaaattat ttagtttcag atataaaaga
    34441 ctatgagcca catcaaacgc aaaatcttta tgttataggt ggtgagactt gtaataaaat
    34501 gaaagaaatg agcaatacta caggagaaaa atttacagag atttattctg atgatgtatg
    34561 gtcaacaatg gataaggcta tagagtttgt aaaagaaaaa ttataattta aaatttttat
    34621 ttaaacaaga atgtagataa gaaaaattta tatcaaaatt tttcttatct attttttctt
    34681 ataaatatat ttattaaagt tataaaagca tatatttcta gaaaaaatgt gttttttgac
    34741 tatttatgcg tttttgatga ccagttagac aataaggatt gaatattttg aatatttgtt
    34801 ttattcttaa aaaaaaataa atatatataa ataattatat atatttattt tttttaaaaa
    34861 taaaattaag aggtgatttt atgaatttag attttcacta ttatggcaca tatcttgcag
    34921 ctaaagtagc tggttataac gacactgatg caaagacaat tgcttatgct gctcagtatg
    34981 tagatgaatc agataaaagt atgattcttg atgatgtaaa ctttacactt ccgacaatac
    35041 agactaattt agaatttaaa aaatattatg cagatttggc ttcatggggt tataaatggg
    35101 atttcgagag tttaaatgaa ataaagaaag tatggatacc atttcatttt ttacctggga
    35161 atttaaacaa ccaatataaa tataatggag ttaaagagag taaatgttta acgacaagtt
    35221 ggaaatttaa agatggagat gaccaaaaat ttaggttgat gtgtttacca aatagcgaaa
    35281 ctgtttctgc cattataaat gaccttattt attttcatag taccgaagaa tataagttac
    35341 aatttattgg aatgagaatg catgtacttg cagacacgtg ggcacatatg tattttattg
    35401 gaaaaccaga atggtatatt aatgatgtta aagaatttat agcagaagaa agtaagtaca
    35461 tagaagaaac taaatggact aaagcagaag aatatcgtaa taacggttgg cattctatta
    35521 actttactgg tactcctgat attggtggat atgagagcat atcatatctt ggacatggta
    35581 gaatggggca tataccagac tatggatatc taaattatag atatattcca aactggagta
    35641 gtactgatga taaagtgaag atagaaaaaa ataaccaaga taatttcttt aaggcatttt
    35701 gccaaatggt ttatgcatta aaatgtatta aaaatggaaa tgactttaat ataaatcaat
    35761 atgataacct aacagctcaa caaaaaacag aagtttcaaa agtaatagca acaagaaaaa
    35821 atgaccaatc agaagcatgg aaaaaagcaa tacaggcatt aggatataac cctttagaaa
    35881 aatttgataa aaataagtgg aaaaatgaat ttataaaatc ttctaataaa gagaaaacag
    35941 attactatta ttttaatcta gtagctaaga aacatgtaga ttatgtaact gattttttag
    36001 aggaaaaaag attgtcttta gaagaaatgt tcaatggata ttgtaaattt aaaaattttg
    36061 atgataccca atttgctaaa aatagaaata gagtgacaaa gattatactt agaggagctt
    36121 atatagttga tgctatacaa cttgtatatg atggaaaata taaaactcca atgcatggtg
    36181 aaccatttgg aggaacaatg gtatctcttg atttagatac tgacgattac atagttaaga
    36241 taagtgggtc tataggttta tatgaaggtg gagaaccata tcctaattct ccaactagaa
    36301 caataggaaa aataactttt ttaactaaaa aaggaaaaac aataacagca ggtcatgaaa
    36361 ctatgtttaa attatataga aatttcactt tagaagcacc tgcaggaaaa caaatttttg
    36421 cacttaaagg ttcatattta atacgtaaat taagagaaga gactagcaaa cgatatttgg
    36481 attgtttaga aattgcaaat acaaaagatt gttcggtagc tacaagtacg aaataactac
    36541 atattggata gctagtgtta taatatattt aagaaaatag tataatattt atatttacaa
    36601 tgaaagcact ctttattata aagagtgctt tcattgtaaa tcatcaagaa cattactaaa
    36661 tataccttaa aattgattta aataggtctt tttatttaga aataacagtc atataagtta
    36721 aatattaata tctaaacaat ttaataatga atatagaaag attaaaaggt agcaactaga
    36781 actagttatt accttacttt tttctgattt tttatatcta acaatttttg ttatttgtat
    36841 aactataaag ttaatataag aagatatttg taagtaagag tatatgaaaa tataataatt
    36901 tatatttaat aaataattta tattaaaatc ataaaaatat ttcgattatt ttaatataaa
    36961 taattaatca tagataagat atatttttga attattgcta aatttatcaa aagatgataa
    37021 aatcaggaaa tgtgtattat ttttatagaa ggaatattaa gtgaaatgta ctaataaaaa
    37081 aatacttatt ttatcattat cgataataac aattttggct tcagtaggag aagtaaatgc
    37141 actagaagtc aaaaataata gcaatttaga aaaacaaaca ataaaggaga ctgttgtacc
    37201 tgagttagta ggattaaaaa tgcaagaagc ttttccagat gaaaatttta gaaaatgtat
    37261 ttctgatatt ttgaatatta aagatagtgg tgatactgtt ataaccgacg aaatgaaaaa
    37321 aactattgaa agcactacaa tattatacat aacgactgaa tctataaaag atttaacagg
    37381 aattaattat tttactggac taaaagaatt acattgttct tctaatgaac taaaggaatt
    37441 agatgtaagt aaaaatacaa aacttagaaa tttatattgt gataacaata gactagaaaa
    37501 attagatatt actaacaata aaaatcttgt acattactct tggggaaacc agaaagagcc
    37561 agagaaaccg tctggaggag gttcttatac tccaactcca atagttacaa aaataaattc
    37621 tttagtaggt tctgatagat atgctacctc aataaaaata agtaaacaat gctgggataa
    37681 tgcaaataat gtagtactta taaataattc tagtatagca gatgcattat cagctacacc
    37741 atttgctaaa gttaaaaatg caccaatatt acttactcaa aataatagtt tgaatcaatt
    37801 gacagaaaat gaaataagta gattaggtgc aaaaaacata tacataattg gtggatttaa
    37861 ttctatagat gaaagtattg aaaattatct aaaagataaa ggtttaaata caataagaat
    37921 atctggaaat gatagatatg atacttcaat aaaactagca aaagagttaa gtaaggagaa
    37981 taaattatct aaattagttt tagtaaatgg agaaaaaggt cttgctgatg cagtaagtat
    38041 gggagctata tcagcaaaag aaaaaatgcc aattcttctt actaatcaaa atgatgatat
    38101 gaaggaaata gaagaactaa ttgataataa agatatatca aaatcatata tagttggtgg
    38161 agagagttta ttcaataaag atatagaaga taaacttcca tctgtaatta aaatatcagg
    38221 agaagataga
//
LOCUS       DBGJFK010000032        37515 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.032, whole genome shotgun sequence.
ACCESSION   DBGJFK010000032 DBGJFK010000000
VERSION     DBGJFK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37515
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.032"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            420..1130
                     /locus_tag="ACOIAP_001925"
     CDS             420..1130
                     /locus_tag="ACOIAP_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGZ2638808.1"
                     /translation="MIKIAICEDEKEQQELLKRYINQIFDALSVKCRLEVFNSGEELL
                     EGYSKDTDVLLLDIQMGQINGIDTARKVRVLDDKVEIIFITALIEYALEGYEVRAYRY
                     LIKPVKYNNLKDNIINCIKEVDIKNKYIMVKAQGSQTKLNVNEITYIEVQKETITIHT
                     LNEVYKINGTMSNIEKEIDCSRFFRCHKSFLVNLEHVKSIKQYVAILENSKEVPVSRY
                     RFKETKDKFFDLIEEKLC"
     gene            1124..2461
                     /locus_tag="ACOIAP_001926"
     CDS             1124..2461
                     /locus_tag="ACOIAP_001926"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2638809.1"
                     /translation="MLDSVYSLAIINMVIFIALFFMLMNKIGYTYRCKTNIQLILILI
                     LSAILIINGMPFGIVPLHALIRIILILSLICKITYQINIKKATINSVIYSLLYILIGC
                     SMYWILQFSWKYVGHYILKANTVINFIIIFIGVYFFDILQKIYNNKKYYLYIILTIAV
                     NVVIVLFVNISTEKMDDLYTIVTKNHIEYSYNVYTMYFSLFMKNTFPYILFIVNVLLI
                     SIFINSIKSEKEKIKAEFVSEKLDMQYKYYFMVKESQEKMRQVYHDMNNHMKNIKSLK
                     NSSEDVNKYINSIEDEVKNTKNIYNTGNVLLDIILYEKSRLCMENNIDFNVGIDFSKC
                     EFIEMIDVSSIFSNLIDNAIEACSNIDDNNIEKYITIKSTFIKGYYIIRCENSKMNKV
                     IIKNNKIFTSKKDKFLHGIGIESIKSSIRKYNGELKIKDSEYKFIVTAHIPIE"
     gene            2638..5205
                     /locus_tag="ACOIAP_001927"
     CDS             2638..5205
                     /locus_tag="ACOIAP_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638810.1"
                     /translation="MTTFKLAVSYMKRQKGKTVALLSCIVLAVMLIFSMIVIRDSGYD
                     SQIKEAKDLHGDYHIWFEGLEKDKTQDLTNEEGISKSNTSKELCEVVDKESGVKLYLN
                     SFDKGFLSSLGYKIEGREPIKDGEIVIEKEATRQMGISNPLNKNIDLMLLNKYIDDNE
                     INHMDSANKTFKVVGVIEKLDKYYDKSRYSITLRAFVYKDSNLPIKIKDTYNGTIYLK
                     SEKNIPQFITKMTKKIDTNVFNLHENGEVDLAKNQRQNSKFSKENIINSVLLVSVSTI
                     VIYNIFNIIFQDMTSQIGIMKSIGMSNKKVRNMLIIMSFIYIILGTLVGIVFGMIFSY
                     VGLRVVYGYSSMLTIQISSVICSFAVSIISVFISSFIVIKKFRKMSIIEAIRSSDKYE
                     KKSKNDNKKIDGKSKNLLISMATRNLWRNKPRTILTILAITLVGIMFILNLGAKSLLK
                     KNMEEGITGGSWSMSYGSVDKTVEGDSRSSESLFYKLDNNLIQKVNGMKGVRHVEPHF
                     YNHRGHILLSKNKLSKAYKDELDRKNSSYQEEHNNEYPLLIRGYSDDMLKQRQEFIEK
                     GENILSTTSGKYKKVILVNNTNSQVTHSFDAKIIDDVKIGDIIEIKLPVYRDGIEKYE
                     NFKVEVGAIMKELYASSQDGNTQAQGAQMIFKENDYKELTGQKEYNKLFVIVEKGQLY
                     SVERRLEETTKNYGSTEINGKGEELKLIGMQQSSEERLSVIYQFLTILILAVNIIFIM
                     RSNIITRRKELATLRAIGMSIKSIKKILIIESQMYGMVASIIGAIIATVYHNYGLAKT
                     NKVLLEGGYTRIIEPNIPFSQIIILFTIFIAMGFISIYVSKDKIEGTTITEGISQNN"
     gene            5279..5947
                     /locus_tag="ACOIAP_001928"
     CDS             5279..5947
                     /locus_tag="ACOIAP_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638811.1"
                     /translation="MKKLAIKNIKKVYGKGDNKVYALNGIDLEIQPNKFTTIVGQSGS
                     GKSTLLHCMAGLDKPTDGKVFIDDLDLYTLNDDKLSKIRREEFGFIFQSYNLIPVINV
                     YDNIVLPISISKRKIDKDYIIDLIAKLGIKSQIDKFPNELSGGQQQRVAIARALANKP
                     SIIFADEPTGNLDSKTTNEVVKLLKLCVYEYKQTLVMITHNAEIANNSDNIINISDGK
                     IVLI"
     gene            6210..7070
                     /locus_tag="ACOIAP_001929"
     CDS             6210..7070
                     /locus_tag="ACOIAP_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGZ2638812.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKVLNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMYALKLIGDSKEINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVEIDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            7060..8931
                     /locus_tag="ACOIAP_001930"
     CDS             7060..8931
                     /locus_tag="ACOIAP_001930"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGZ2638813.1"
                     /translation="MKYKDLNENIIKLTGGKENIKSVAHCVTRLRLTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSVKGERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILHSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWSMGIIIGGLKKILPKALHYFLVPVLSLIITLSVTLTIFGPIGMWIGDVLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPIALNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGL
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEMSNFTFMIIAVLVSFVGATVASYLLGIP
                     SDEKEEAKNANEKELELVVNEDNSRTISVGSVAKGQVISLEEVNDKAFSSGALGKGVG
                     VIPSESKSTVMSPVDGTITIVFQTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFDSDKIIEAGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            8951..10393
                     /locus_tag="ACOIAP_001931"
     CDS             8951..10393
                     /locus_tag="ACOIAP_001931"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGZ2638814.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYECLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     KKFDGKVRHWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNINIEVTDEDKKAFEEGRLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPVGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDNY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKFNGENLNLLDV"
     gene            complement(10672..11199)
                     /locus_tag="ACOIAP_001932"
     CDS             complement(10672..11199)
                     /locus_tag="ACOIAP_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HGZ2638815.1"
                     /translation="MKKEALEVLKNRRSIRKFKSNQVSKEELDLVLEAGTYAPTSKGS
                     QEPIIIAVQDEDTVSQLDALNARILNIEKTPHPYYGAPTILLILAPEDALIPVENCSL
                     VAGNLMNAAYAVGLGSCWIHRAKEMFESIEGKELLKKWGLPETLKGVASIALGYPDCP
                     HPKAASRKEGYILRV"
     gene            11343..11780
                     /locus_tag="ACOIAP_001933"
     CDS             11343..11780
                     /locus_tag="ACOIAP_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGZ2638816.1"
                     /translation="MRMSTQFTVSVQMLLLIMVLDDRKVTSEMISKSTGGNPVMVRQL
                     FGKLKEAGILNVSAGRGATVLAKKPSEISLWDIYMAVEEYSSSELFKFHPKISEGCNI
                     GRFFKEILGNHLDEAIHAMADKMSKVSLAQLLEEWESVNKESK"
     gene            12968..14176
                     /locus_tag="ACOIAP_001934"
     CDS             12968..14176
                     /locus_tag="ACOIAP_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638817.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLI
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALIGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPNMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTSIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            14207..15586
                     /locus_tag="ACOIAP_001935"
     CDS             14207..15586
                     /locus_tag="ACOIAP_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2638818.1"
                     /translation="MIGSISINEIDKKRFKLDDLSRKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEIGVGGLATAIKASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGIKREMIENNLGGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYIRALSREAVESTYERLVKVAKG
                     ATMMTETEVEVEFLGGCYNTLNNHTLANLVSECMNEIKQEPWTQEELDFAAELDRQSP
                     QQYKDMISKYNLQEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYAAKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(15963..17291)
                     /locus_tag="ACOIAP_001936"
     CDS             complement(15963..17291)
                     /locus_tag="ACOIAP_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638819.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDSFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQDAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTTCYIKESIENSINIKVCIGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(17901..19115)
                     /locus_tag="ACOIAP_001937"
     CDS             complement(17901..19115)
                     /locus_tag="ACOIAP_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGZ2638820.1"
                     /translation="MRNCIIAQSGGPTAVINASAIGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYRINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFILETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASGTDLKQAADVGAYGIELSKKEYTGVMAII
                     NRTCNNPYKYEVGHTDISKIANKTKYFPKEWINEECNYITDEALDYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            19523..20239
                     /locus_tag="ACOIAP_001938"
     CDS             19523..20239
                     /locus_tag="ACOIAP_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGZ2638821.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTVGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIA
                     AGVKNCRKAIDEAATKFGLE"
     gene            20374..21000
                     /locus_tag="ACOIAP_001939"
     CDS             20374..21000
                     /locus_tag="ACOIAP_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2638822.1"
                     /translation="MKKEMIKDYLLITVSAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPFFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINSTCTQ"
     gene            complement(21184..22728)
                     /locus_tag="ACOIAP_001940"
     CDS             complement(21184..22728)
                     /locus_tag="ACOIAP_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2638823.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEKLNVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLQTLQVEK
                     SNLSDEYYINFLIHIAICIRRISIKRYINLSEGFFRELLEHEYFEKSKILCSNLGEAF
                     DVEFISEEVCYILLHVEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGNILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(22754..23395)
                     /locus_tag="ACOIAP_001941"
     CDS             complement(22754..23395)
                     /locus_tag="ACOIAP_001941"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase family protein"
                     /protein_id="HGZ2638824.1"
                     /translation="MKYLIDSANLDEIQKCLKCGFKGITANPSMYLKENINFYEFIET
                     CTNLNPEILTAEVIGNNLYELINSCDKILNINKDTIIKINFSEIGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICDLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTVDGANTFERDWSKVNK"
     gene            23666..24817
                     /locus_tag="ACOIAP_001942"
     CDS             23666..24817
                     /locus_tag="ACOIAP_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGZ2638825.1"
                     /translation="MINFYQPSRINFGQGTISELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLDLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNVDKFAKVARMLNQELEKVEDNEAAKTLGKEIER
                     FLKNVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            24830..25642
                     /locus_tag="ACOIAP_001943"
     CDS             24830..25642
                     /locus_tag="ACOIAP_001943"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGZ2638826.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAIKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGQEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVESLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIEFAGLGIAMGNATDEVKSIADFVTDTNVNDGVAKALRKVLS"
     gene            25668..26159
                     /locus_tag="ACOIAP_001944"
     CDS             25668..26159
                     /locus_tag="ACOIAP_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGZ2638827.1"
                     /translation="MFNIFKKKENKVEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVSVFDTKHAITIKSNDNTNMLIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            26655..27356
                     /locus_tag="ACOIAP_001945"
     CDS             26655..27356
                     /locus_tag="ACOIAP_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGZ2638828.1"
                     /translation="MINIAICEDNFVDRGILNDYLIRIMNENSYNISLFKSGEELLDN
                     YPDDLDILLLDILMKKINGIDTAKKIREFDSNVEIIFITSLLEYALQGYEVKAFRYIL
                     KPIEYEQLSINIIQCLDDINNKASKFVYIKCNSDIVKIDIESILYIEKISRYIFVYTE
                     DQVYKSKMNLKDIEKKLQHYKFYRCHLGYLVNVNKIDCLGSSEVSIYNHSIPVSRGKR
                     KILKEFIIDSKEKSL"
     gene            27944..28651
                     /locus_tag="ACOIAP_001946"
     CDS             27944..28651
                     /locus_tag="ACOIAP_001946"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF025854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2638829.1"
                     /translation="MIFNLYLLSMMDKLLESRRIEIENKFMKEKIEIEYKYIKKLQYS
                     NENIRILKHDIKNHLICIRNIHNNKEAFDKYLDSVDIEVNKINDIYDTGSIIVDAILD
                     EKKIICDNYNIKLYVKANFTGCDFISAFDLCTIMSNLLDNAIESNLKVKNSDCRNITV
                     KANCEKYMLIIIVENNKSNKIIKSKQSIITDKKNKTIHGLGLKSVKKSISKYNGDLFV
                     EYNDENFKVKIIIPTNI"
     gene            28745..28918
                     /locus_tag="ACOIAP_001947"
     CDS             28745..28918
                     /locus_tag="ACOIAP_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638830.1"
                     /translation="MIKIKKITDKEKVVVSAQAKKPCSCAGQVLKYPPVSNSCLYDYD
                     DYNQPRWYEAQCQ"
     gene            28991..30250
                     /locus_tag="ACOIAP_001948"
     CDS             28991..30250
                     /locus_tag="ACOIAP_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="HGZ2638831.1"
                     /translation="MNYKFDDSVKLLKNGEYVILGNTKNGQWIKMTNYIYNIFKIGID
                     NSLDINELKKCLEDDEDRQFIQNLYENLLDMRIIYDEINNVAFQNKIASLEITNRCNL
                     KCVHCCVDADNLISEKEELSTIELKDAIKKIVEWNPMNIMLSGGEPMVRSDFFEILTY
                     LKSIYKGNIIVSTNATLINKNNVELLIKNVNKLEISLDGVNEQTCSIVRGKGVFKKVI
                     DSVNLIKSFGFDNITLSMAVGNKNEYLEEEFKDLCKNLGVGHMIRRFGPVGRGKENEH
                     LFLDNNKDEAYIPENFLKDNYDGNMGVTSCKAGIYEIFIRHNGDIYPCPSFMSDEYKI
                     TNLCDIQQISEIKDKYINKVDVFSILEKINPEIYKNCIDCNVNLFCWTCPGEIEELKD
                     SKASLFNKCSKIKNILYKRVWGNDGVC"
     gene            30244..31260
                     /locus_tag="ACOIAP_001949"
     CDS             30244..31260
                     /locus_tag="ACOIAP_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="HGZ2638832.1"
                     /translation="MLATFWITNECNMKCRYCYEGNNKNNKVMSKTLIDKSISYVLNQ
                     SNSLDDDELVIQIHGGEPFLEFNLIKYIISEFKSEKFNKNIIFSTTTNGMLLNNDILD
                     FIQLYIAELTISIDGAKNTHDKNRQSINGKGTHDIVIENSRKILKIKPNVRVRMTFDT
                     ETVGNLSNDIKYLISEGFRTIVPVPDMFETRWNNNHIEVLKNQIYQIKEIIGNSKDIL
                     VSLTDTNIYKYKGVCSGGKLSFNICPDGYIYPCTLAVGNKDFSIGNIYDGIDKTSRDK
                     FLSKSYLDNNDCKGCDLSNSCDGNRCKIINKLTRGSYFLPSPINCAIQNIKHEINISK
                     EIVL"
     gene            31286..32341
                     /locus_tag="ACOIAP_001950"
     CDS             31286..32341
                     /locus_tag="ACOIAP_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGZ2638833.1"
                     /translation="MKRIKVALIDSGIDINHKYLKNNILYGKSYIYKDNKIVVSNEIE
                     DINGHGTSCASIIKSEYEYVDFIIIKIFDRDGLTNIKVLEESLNYLISIDVKIINLSL
                     AIHGDINSCKDLYKICEKLKNQNKIIVSSLANYNYIEESYPSIFDNVIGVKGNLLKKR
                     SSFWYNSEYKYQCVVDDSDRIVADLGNSFKLVEKSNSFSAAKMSGKIAKIIANKVDIS
                     FDGLSRILEELSECTNWKDEDLYTNKRRIDYKQYLYENNNINLNRVLKVLVDNLNIGC
                     NVDILFDSILFSKYIGLKNNNCIEILKKLENEFNIKIDYTKVYKEDLISIYTLTNLIE
                     KESICEHFRNCKYLQKL"
     gene            32301..32966
                     /locus_tag="ACOIAP_001951"
     CDS             32301..32966
                     /locus_tag="ACOIAP_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638834.1"
                     /translation="MNILETVNISKSYSIGDKKSYILKDINIKIKEGEFISIIGPSGS
                     GKSTLLHILGGLENPTTGIVKIIGKSIYDLSEIKLAEYRRRRFGFIFQQFNLIPVLNV
                     RENIEMPLMLDRAKIDNRFIKEIIEFLGLEEKENYYPNQLSGGQQQRVAIARALVSKP
                     DIIFADEPTGNLDTKNSDEVIKLLMKSIHKYNQTVLLITHDYKIAKNTDRTIKILDGK
                     LEL"
     gene            32994..34742
                     /locus_tag="ACOIAP_001952"
     CDS             32994..34742
                     /locus_tag="ACOIAP_001952"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638835.1"
                     /translation="MKNTINMKKFLYLIIQGNKKLVIISFLMMIVVAMIDLYIPQIIR
                     NILDIAIKSKNITMLIKLILQFILINIILSNLELFLEYNYSKMKKKITTKLKLKLLRH
                     LSKLDGRFFSEIKTGNIMNIVEYDVMMLDRFGIELIFSLIVDIITAFISLYFLIKIQS
                     KLLVIVVVIQIVISFTQYIFTKMISKYTQNIRSNAGSISNIVQEYISNIMNVVIHKGE
                     LNFFTQFLSMQKNFVSKCIKLDMIMAGNVSLSKILNSLIVISIYGYGGYKIINGEITF
                     GELVAFQQYTGMLIGPCMNIIKSNAIVQQSLVSINRIFDLLNEEVNMKQENTGEIFQS
                     GITKKIRMDMIDVSFSYDKEDVLHNINMSLESGNIYGIVGGSGSGKSTLIKLIYRLWD
                     IESGSIRINDVDIRDYNLKNLRKNITIITQEPLLLNDTVFNNIILSNKNINYELVVRI
                     CKELDIYDFIVSLPNEFNTIVGENGVKLSGGQKQRISIARAMLSNSSILVLDEATSAL
                     DNISQKDLLKSMKKFLNNKIVIIIAHRLSTIKDSDKIFVINNGEIIESGSHKDLVSQN
                     GYYCNLLEDKKEYSYC"
     gene            34912..37443
                     /locus_tag="ACOIAP_001953"
     CDS             34912..37443
                     /locus_tag="ACOIAP_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2638836.1"
                     /translation="MRLSLAYVKKYFGRSISIALSIIISISLIITVGILTKNTQKASV
                     DRIKYESGDYHVKVKNISGNVISDYKKQFDISMMGVSSYYDSSEFNGKLMLNLIKSNE
                     DYIKIYNSKILNGRFPTSDNEVALEEWVMLNLGLKLDINQNIKIKLYNSKETKNYKVV
                     GILKDRPYYKSIGMAELILPFTENIIKETNLEAQIRFKKDIYRNLSKLMNDNHISRKN
                     VSENRILLDALGESNGLNYDFIFTCIISMIVSGVVIYSIFRISIIQRISEYGIIRALG
                     ANIFNVFNIIFVELFAISLVSIPIGVLIGIISSKYITLFMGNLLIGNIVKINNVEINL
                     DVVMISIITVLVNILIISFLTCTNVNKISPIKCIKKDISKKNSRESSILNTRRLLNLL
                     PIEYIISLKNILKNKKNFVIIVLSMSGGCIIFILTNFTNILDERQLEYTSKVATENSD
                     YNISFAPVTPLNIGISEENLKQIRQLEGIENVKTSQVMYSRMILNKDNINNMNYFEKV
                     NKSAYNKKALNGLLVKKDNEYILKSNLYGYDNSSIDAQKSFVISGDIDLDKMNNGNVA
                     ILYMPDPSLFTNIKDSRPVLNLKVGDIVKLRFRSDYVSDENFAKLKDKGEYVEEEFKI
                     GAIVSNILNVDGYYAGMDSASIIISQNQFKNIVGIHSYRMLDIKKIPTVDNIELGKNI
                     IDISSKIQGSIVRDFTQEIKNIKIIEDNKKILIYTIILVLFTISFINIINNINYNLYS
                     RINEFGVIRAIGLDNNSFRKMLLFEGVVYGLISASVSITFGILGQSILYNILKGNLMN
                     AKFIIDYKSYILVIILTIILGVVATYLPSKKVKKLSIIESINIIE"
BASE COUNT        14864 a         3821 c         6051 g        12779 t
ORIGIN      
        1 tttaagattt tatatataaa catataattt atgatatctg aaaattttat agtatttaag
       61 taaataaaaa tatatgtaat aaataaaagt agtgtatgat tagtttattt atctttaagc
      121 ttatgaaacc tatacaagtt tatatattaa atatatagaa tataatttta taatttgata
      181 aaatgaataa aagtatatat tagaaaaggt tgatttatga aaaatatata cataatatta
      241 tcttaaatat taaaagagta tactgcataa aaaataataa tcacttatga gtattccata
      301 ataactcata aatgattatt atttaagaat aaagtacgta actgaataag aagattaaga
      361 aaagttttag ctttgttaag aataatttaa gtatataaat gtgtatgggg tggaattagt
      421 tgataaaaat agcaatatgt gaagatgaaa aagaacaaca agagttgttg aaaagatata
      481 taaatcaaat atttgatgca ttgtctgtta aatgtagatt ggaagtattt aattcagggg
      541 aagaattact tgaaggatat tcaaaagata ctgatgtact tttattagat atacaaatgg
      601 gacaaattaa tggaatcgat actgcgagaa aagttagggt actggatgac aaagtagaaa
      661 ttatatttat tacagcatta atagaatatg cactagaagg ttatgaggta agggcttata
      721 gatacttaat aaaaccagta aagtataata atttaaaaga taatataata aattgtataa
      781 aagaagtgga tataaaaaat aaatatatta tggtaaaagc acaagggagt caaactaaat
      841 taaatgtaaa tgaaataaca tatatagaag tgcaaaaaga aactataact atacacactt
      901 taaatgaagt ttataaaata aatggcacaa tgagtaatat tgaaaaggaa atagattgta
      961 gtagattttt tagatgtcat aagagttttt tggttaattt agagcatgtg aaaagtataa
     1021 aacagtatgt tgctatactt gaaaacagca aggaagtacc tgttagtagg tataggttta
     1081 aggagacaaa agataaattt tttgatttaa tagaggagaa attatgttag atagtgtgta
     1141 tagcttagct attataaata tggtaatatt tatagcttta ttttttatgt tgatgaataa
     1201 aattggttat acttacagat gcaaaactaa tattcaactt atattaattt taatattatc
     1261 tgcaatctta attataaatg gtatgccttt tgggattgtg ccattacatg ctttaataag
     1321 aataatttta atattatctt taatttgtaa aattacttat cagattaaca taaaaaaagc
     1381 tactattaat tctgttatat atagcttgtt atatattttg atagggtgta gtatgtattg
     1441 gattttacag ttctcatgga agtatgtagg tcattacata cttaaagcaa atactgtaat
     1501 aaattttatt attattttta taggtgttta tttttttgat atactacaga aaatttataa
     1561 taataagaag tattatttat atataatttt aacaatagca gttaatgtag ttatagtttt
     1621 atttgtaaat atatcaactg aaaaaatgga tgatttatat acaatagtaa caaagaatca
     1681 tattgaatat agttataatg tatatacaat gtatttttca ctttttatga aaaatacatt
     1741 tccatatatt ttatttatag taaatgtatt attgatatct atatttataa attctataaa
     1801 atcagaaaaa gaaaaaatta aagcagaatt tgtaagtgaa aagttagata tgcagtataa
     1861 atactatttt atggtaaaag aatcacaaga aaaaatgaga caagtatacc atgatatgaa
     1921 caatcatatg aaaaatataa aatcgctaaa aaacagtagt gaggacgtaa acaaatatat
     1981 taatagtata gaagacgaag taaaaaatac taaaaatatt tataatacag gaaatgtact
     2041 attagatatt atcttgtatg aaaaaagtag attatgcatg gagaataata tagattttaa
     2101 tgtaggcata gattttagta aatgtgaatt tatagaaatg attgatgtaa gtagtatatt
     2161 ttcaaattta atagataatg caatagaagc atgtagtaat attgatgaca ataatataga
     2221 aaaatatata actataaaaa gtacctttat aaaagggtat tatataatca gatgtgaaaa
     2281 cagtaaaatg aataaagtaa taattaaaaa taataagatt tttacttcta aaaaagataa
     2341 attccttcat ggcataggta ttgagagtat aaaatcttca ataagaaaat acaacggaga
     2401 attaaaaatt aaggatagtg agtataaatt tatagttact gcccatatac caattgaata
     2461 aaaattcaat agattgatgc atttaaaaag cttataagct agtctttaat atgctagttg
     2521 acggtgaaaa aataccactt gtcggactta tattgaataa aaattttaaa aatgttacct
     2581 ttacaaaaaa ggtagcattt tttatacaag gatttaatag aagaaggagg taaagttttg
     2641 actacattta aactagcagt ttcttatatg aaaagacaaa aaggaaaaac agtagcacta
     2701 ctatcgtgta tagttcttgc tgtaatgctt attttttcta tgattgtgat tagggattct
     2761 ggatatgatt cccaaataaa agaggcaaag gatttacatg gtgattatca tatatggttt
     2821 gagggactcg aaaaggataa aacacaagac ctcacaaatg aagaaggtat atcaaagtca
     2881 aacacttcaa aagagctatg tgaagttgta gataaagaaa gtggtgttaa gctttattta
     2941 aattcatttg acaagggttt tctaagttct ttgggatata aaatagaggg aagagaacct
     3001 ataaaagatg gagaaatagt aatagaaaaa gaagctacaa ggcaaatggg gatatctaac
     3061 ccattaaaca aaaatataga tttgatgctt ttaaataagt atattgatga caatgagatt
     3121 aaccatatgg atagtgcaaa taaaacattc aaagttgttg gtgtgataga aaaattagat
     3181 aaatattacg ataaatctag gtatagtatt acacttcgag cttttgtgta taaagactcc
     3241 aatttgccaa taaaaataaa agatacgtat aatggaacaa tttatcttaa atcagagaaa
     3301 aatatacctc aatttataac taagatgaca aaaaagatag ataccaatgt ctttaatctg
     3361 catgaaaatg gtgaggttga cttagcaaag aatcaaagac aaaattcaaa attcagcaaa
     3421 gaaaatatta taaattcagt gcttttagtc agtgtatcaa ctattgtaat atacaatatt
     3481 tttaatatta tttttcagga tatgactagt caaataggta ttatgaaatc tattggtatg
     3541 tcaaataaga aagtaagaaa tatgcttatt attatgagct ttatctatat aattttagga
     3601 actctagtag gaatagtatt tggaatgatt ttttcatatg ttggtttaag agtagtgtat
     3661 ggatacagct ctatgctaac aatacaaata tctagtgtaa tatgttcttt tgcagtttca
     3721 atcatatcag tatttatttc tagctttata gtaattaaaa aattcaggaa aatgtctata
     3781 attgaggcta taaggtcaag tgataagtat gaaaaaaaat caaaaaatga caataaaaag
     3841 atagatggaa aaagtaaaaa tttacttata agtatggcaa ctagaaatct atggagaaat
     3901 aaacctagaa caatattaac aatattagca attacattgg ttggaataat gtttatctta
     3961 aatctaggtg ctaaaagttt gctaaaaaag aatatggaag aggggataac aggtggttca
     4021 tggtcaatgt catatggaag tgttgataaa actgttgagg gagattctag aagttcagaa
     4081 tctttatttt ataaattaga caataattta atacaaaaag tgaacggcat gaaaggtgta
     4141 aggcatgtag aaccacattt ttataatcat cgtggccata ttttactttc taaaaataag
     4201 ttatcaaaag cttataaaga tgaattagac agaaaaaatt cctcttatca agaggaacat
     4261 aacaatgaat atccactttt gataagaggg tatagtgatg atatgttaaa gcaaagacaa
     4321 gaatttattg aaaaagggga aaatatacta agtactacat ctggcaagta caagaaagtc
     4381 atcttagtta acaatacgaa ttcacaagtt acacattctt ttgatgcaaa gataattgat
     4441 gatgtgaaaa taggagatat tatagagata aagctacctg tatatagaga tggtattgaa
     4501 aaatatgaaa actttaaggt agaggttggt gctatcatga aagaattata tgcatcaagt
     4561 caggatggga atacacaagc tcaaggggct caaatgatat ttaaagaaaa tgactataaa
     4621 gaattaacag gtcaaaaaga gtataataag ctttttgtca tagttgaaaa gggacaatta
     4681 tattctgtag aaagaagatt agaagaaacc actaagaatt atggatctac tgaaatcaat
     4741 ggaaaaggag aagaactaaa acttattgga atgcaacaaa gttcagaaga aagactttct
     4801 gtaatatatc agtttttgac tatattaata cttgcggtga atattatttt tattatgaga
     4861 agtaatatta ttacaagaag aaaagagctg gcaaccttaa gggcaattgg aatgagtata
     4921 aaaagtatta aaaagatact aattattgaa agtcaaatgt atggaatggt agcttctata
     4981 ataggagcta taattgcaac agtatatcat aattatggtt tggctaaaac gaacaaagtt
     5041 cttttggaag gtggatatac taggataata gaacccaata ttcctttttc tcaaataatt
     5101 atactattta caatttttat tgctatggga tttatttcta tatatgtatc aaaagataag
     5161 atagaaggta caacaataac agaaggaatt tcacaaaata attaaggcta tggaatgaca
     5221 agataaaaat gtaatactat ttagtgggat ttaaataaga agaatggaga accgtattat
     5281 gaaaaaatta gctataaaga atataaagaa agtatatgga aaaggggata ataaagtata
     5341 tgcattaaat gggatagatt tagaaataca acctaataaa tttacaacta tagttgggca
     5401 aagtggctca ggcaaaagta cattacttca ctgtatggca ggtcttgata aacctacaga
     5461 tggaaaagta tttatagatg atttagattt atatacccta aatgatgata agttatcaaa
     5521 gataaggaga gaagagtttg gatttatatt tcaaagttac aatctaattc cagttataaa
     5581 tgtttatgat aatatagtac ttcccatttc aattagtaaa agaaaaatag ataaagacta
     5641 tataatagat ttaatagcta aactaggtat aaaatctcaa attgataaat ttcctaatga
     5701 attatctgga ggtcaacaac aaagggtagc aattgctaga gcacttgcaa ataaaccttc
     5761 aataatattt gcggatgagc ctacaggaaa cttagatagt aagacaacta atgaagttgt
     5821 gaaacttcta aaactctgtg tatatgagta taaacagaca ttagttatga taactcacaa
     5881 tgctgaaata gctaataatt cagataatat tataaatatt agtgatggta aaatagtatt
     5941 aatttagtat ataaactttg caagataatc gcctacagag tctgtagtta tataattaaa
     6001 aaaatattta ggaaaccgtt gacagattta catagatagt ataacatata ggatataaaa
     6061 ttaaacgaaa aagaatttta attatggcga cgtagtcata attttgagta tgttactgat
     6121 tagcaggcag aactcaagta tatatgtgaa aaatagaggg atactctata catatatgct
     6181 tgagttcttt ttattgaagg gaggaatata tgaaaataat tcagatttta aataataatg
     6241 tggccttggt aaaaagaggc aaaaatgaaa ttattgtatt tgttaaagga attggcttta
     6301 aaaaaagagt aggacaagta ataaatgaaa atgaaataga gagaacatat atattagatt
     6361 catacgatat gttagaacac tttagttatc tattacaaaa ctcagactcc aataatatag
     6421 ttctcattaa tgaaataatt gaatatggtg agaaagtttt aaatataaag tcaagtgatt
     6481 atctaagttt aaccttacta gaccatttag agtttttact taaaagatgt gaaaagaatc
     6541 aatttataaa aagtcctttg gtatggaatg ttaaaagatt ttatcccaaa cattttgaaa
     6601 ttggaatgta tgcactgaaa ttaattggtg atagcaagga aattaatctt cctgatgatg
     6661 aggcagtatc aatagcactt cattttgtaa atatggaggt aaacaaagag tctcatgata
     6721 gtacgattgt agagttaaga actttagcag atatagtttc tataataaaa tatcatttta
     6781 atgtagagat agatgaaact tcaacaaatt atatgagatt tactactcat ctacagtact
     6841 ttatccaaag aattatgtca gatgaagctt caatagatga agataattct atagatttat
     6901 ataaacaagt aagtcaactt tacccaaagt catttggaag tgttcaaaag ataagaaaat
     6961 atataaaatc acaatttaat gtagatatat ctataagtga agaaacttat ttaatgttgc
     7021 atataaatag ggtgactcaa agactggagg caaaatcaga tgaaatataa agatttaaat
     7081 gaaaatataa taaaacttac agggggaaaa gaaaatataa agtcggtagc acattgtgtt
     7141 actcgtttaa gacttacttt aaatgatagg agtatcgctc aaacagaaga aattaaaaaa
     7201 ttaaaaggag taattgatgt agtttctaat gatgttgctt atcaaattat aataggtact
     7261 catgttgtag atgtatataa cgagtttatg tctatgatag gtttaagttc aagtgaatca
     7321 agtgtaaaag gtgaaagaaa aaagggaatt agaggtatca aaggtatatt taattccatc
     7381 tttgtggtag tctcagaaac tatgacttca gtaattgaag tactacttgc agctggtata
     7441 cttgcaagta tattagcgct tttaaatatg tctggtatac ttcatagtga tagtcctaca
     7501 tatcaaatat tagatacatt aagaagcgct acatttcact tcttaccagt attaattgca
     7561 atagcatcag caaaaagact taatgtaaat ccctatatag cagtagtgtt agcagttaca
     7621 ttactatctt catcaataga tggtgtagaa ggattaagtt tatttggtat aaatttacag
     7681 gctacaacct atgcaaacag ctttattcca atacttttag gagtatggtc aatgggaatt
     7741 ataattggag gtttgaaaaa aatactacct aaagcactac actatttttt agttccagta
     7801 ttatctttaa taataacttt atcagttaca ttaactatat ttggacctat tggtatgtgg
     7861 attggtgatg tattaaacta tgcatgtatg tttttaattg atacattagg aaattggagt
     7921 gttgttgcat tatatgcagc tttacaacca ctcttaatag tctttggcgc agcaaatttt
     7981 actatgccaa tagctttaaa ttctgtgaca acattagggt atgacccaat ttttatggga
     8041 gcagcaacaa tatctgatat tgcagtttgt ggtgcaatgt ttggatattt cttaaaaact
     8101 aggaataaag agcaaaagca attatttggg acagtgagtt ttagtgcact tatgggagtc
     8161 acagaacctt cagtgtttgg tgtgtttatg aaatatagaa gaccatttgt agcagtaatg
     8221 ataggcggag gcttaggtgg cctaatagca ggattagcac aagttaaaac atatggaatg
     8281 gtttggggat tagctgcatt accaacatat cttgttggtg gagagatgtc taactttaca
     8341 tttatgataa tagctgtatt agtatcattt gttggagcaa cagtggcttc ttatttacta
     8401 ggaatacctt cagatgaaaa agaagaggct aagaatgcta atgaaaaaga attagaatta
     8461 gtagttaacg aagataattc aaggactatt agtgttggaa gtgttgcaaa aggtcaggta
     8521 atttcacttg aggaagttaa tgataaggca ttttcatctg gggcattagg taaaggggtt
     8581 ggagttatac ctagtgaatc aaaatcaact gttatgtctc ctgtagatgg aactataact
     8641 atagtatttc agaccaaaca tgcctatggt atagtgactg atgaaggatt agaaatatta
     8701 attcatattg ggatagatac tgtaaacttg gatggaaagt tctttgaaag tcttgtaaca
     8761 caaaatcaaa gggttaaaaa aggagatgct ttagcagtat ttgactctga taaaattata
     8821 gaggcaggat ttgattcaac tataataact gtagttacaa atactagcga ttatttggat
     8881 gtaatctcat caaatgatga atcagaagaa ctattaactg taatagtata aattttagga
     8941 ggggaaattt atgaatatta aagatacatt tttctgggga ggaagtattg cagcccatca
     9001 atgtgaaggt tcatgggata gtgataacaa aggacctgca attatggatt ttgtaactaa
     9061 aggttcttat gaaacaccga gagtaattac tgataaaata gaagaaaaat tggattatcc
     9121 atctcataat ggaatagatt tttataatag atataaagaa gatatagctt tatttaaaga
     9181 aatgggattt agtgcattaa gaatatctat agattggtca agaatttttc caaatgggga
     9241 tgatgaaaac cctaatgaat tagggattaa atactatgaa tgtctgatag ataccttaat
     9301 agaaaataat atagaaccta ttgtaactct atatcatttt gaattaccta tgaacttagt
     9361 acataaatat ggttcatgga ataacagaaa acttatagat ttgtatttaa agtacagtga
     9421 gactgtaata aaaaagtttg atggcaaggt aaggcactgg gttacattta atgagatgaa
     9481 ccatattgac cctcaaacag agcactcgga tatttttact tatatgatag caggtattaa
     9541 gtatagtgaa atagaaaata aggttcaaac actggcaaac gtagggtata atatgacttt
     9601 ggcaggtgta aaggttgcaa agttggctag agaaatcaat ccaaacaata aagttggatg
     9661 tgtatttgga ctaaatccaa tttatccata caattgtaat cctagtaatg tgttaaatgc
     9721 atttttagat aatgaccgtg attattatca aattgatgca atgtgcaatg ggaagtttcc
     9781 tcaatataaa ttaaaagaat atgaaaaaaa taatataaat attgaagtga ctgatgagga
     9841 caaaaaagca tttgaagaag gtagattaga ttttataggt cttaattatt atttttcaag
     9901 tgtatctact ccaaaagaaa atttatcagg tgataaatct ttatttggtg gtattcaaaa
     9961 tccatatttg gaacagagta agtggggatg ggcaatagac cctgtaggtt taagatttac
    10021 tttgaactat atttacagaa agtatcaatt acctatctta attacagaaa atggtttagg
    10081 ggcatatgat aaaattgaag aagatggaac tataaatgac aattatagaa ttgagtattt
    10141 aagtaagcat ctatctcaaa tgaagtctgc aattgaagag gacaatgttg aatgttttgg
    10201 atatttgatg tggggaccaa ttgatttggt cagtgcaact acaggtcaga tgagtaaaag
    10261 atatggattt atatatgttg acttagatga tgaaggcaaa ggaagtttta agagatataa
    10321 gaaaaaatca tttgattggt acaaagaggt aataaaattt aatggagaga atctaaattt
    10381 gctagatgta taaaatgaaa tatgtgttat atgtattatg attatacctt cgattattat
    10441 aaactacaaa taaatttaat ttaccatttt tcggtaagtc actaaaataa taaagttaaa
    10501 caagcattta taagtttagt taatgtttaa agtaaaagca ctcttttaaa gtattatcta
    10561 tatatcagta atgttttaaa tgagtgctta tgtaataatt ttgggttaaa tatagaataa
    10621 aaaattaaaa gcagtttact taaaaataaa gtaattttaa tttttatgta tttatactct
    10681 aagaatatat ccttccttac gagaagcagc cttagggtgt ggacaatcag gatatccaag
    10741 agctatagat gctacacctt ttaaagtttc aggtaagccc cattttttta ataattcttt
    10801 tccttctatt gattcaaaca tttcttttgc acgatgtatc cagcaagaac ctaaaccaac
    10861 tgcatatgca gcattcatta aattgccagc aactaaacta cagttttcaa ctggaataag
    10921 tgcatcttct ggagcaagaa taagtaaaat agtaggtgca ccataataag gatgaggtgt
    10981 tttttctata ttaagtatcc tagcattaag tgcgtctaac tgagaaactg tatcttcgtc
    11041 ttgtaccgct attattattg gttcttgtga gcctttgcta gtaggtgcat atgtaccagc
    11101 ttcaagaact aaatcaagct cttctttact tacttgattt gatttgaatt ttcttatact
    11161 tctacgattt tttaaaactt ctaaagcttc ttttttcata ttcatacact ccttatgtta
    11221 tagtttaatt gtagtcttat tagctacaat taaactataa cataaaataa ttgtagcgtc
    11281 aatagctaca attgacaatt tattttataa attatataat actgaaaagg gagggatgcc
    11341 aaatgcgtat gagcactcag tttacagtat cagttcaaat gctattatta ataatggttt
    11401 tagatgatag aaaagtaact agtgaaatga tttctaaaag tactggagga aatcctgtaa
    11461 tggtacgtca attgtttggc aaactaaagg aagcaggaat cttaaatgta tctgcaggta
    11521 gaggagcaac agttctagcg aagaagcctt cagagatttc attatgggat atttatatgg
    11581 cagttgaaga gtatagttca agtgaattat ttaaatttca tcctaaaata tcagagggat
    11641 gtaatatagg acgtttcttt aaagagatat taggtaatca tttagatgaa gcgatacatg
    11701 caatggcaga taagatgtct aaggtgtctt tagctcagtt gctagaggaa tgggaaagtg
    11761 taaataagga gagtaagtaa taattgaact tatttattgt tgatattatt gaaatattaa
    11821 tattattaaa cttgaaggtc atattgagag attatcaata tggccttatt tatacattta
    11881 gtaatggcat ctatataatt ttacttataa tctatatcaa acaagttaat atatataagt
    11941 attttatcta tgacttttat tcttttaata atatatatat aaatttctag caagaaatag
    12001 tttacatttc actactgtgg tgtgtatact actatgaata tttaaacttt tcctatagaa
    12061 ctttaggcat attaatatat taatgattaa tatgtttgat ttttaaataa tactaaatct
    12121 aataaagaat tatgttagat ggaaaaataa aaaaactata aattatataa tagattagtg
    12181 gttatagagt aaaaataaga tggcagtaaa ctttaaggta tattaataag aagccacatc
    12241 tttaatttta gcataagatt atgaaatcat aaatttacaa attattgtca gaatacattg
    12301 acaaatttat ggtttgaaat tataatctat gttaagaatt gtttgacaat gtaaaactag
    12361 tgattttaga atttagaaga attatttttt atgtctaatt taggaataat ttaagactat
    12421 tataggttta taatttatca ttaatttaat tagataaata ggttttgtct ctaggaataa
    12481 gatttctaaa aacactagaa agagtataat ttataaaggg gggagtagaa gagaaaaaag
    12541 tatatctaca gaaagactta aaacaagaca tattttaata atgttaatga atctgttttt
    12601 aagatttgtt aaggatttta agaataattt aagactctta taaaatggga ttcttatagt
    12661 tagaatttag ataagtataa gtcttctaag aagtatataa aaattaaaaa tagttatagc
    12721 gtaattctaa atttgtaaaa agatgtataa gattaaaaag aaattaagta tatgaataac
    12781 tatggttaag atttaagaaa ttaaccgtgg ttatatttat tcagatattt taagaataat
    12841 ttaagacgct taaaaatcat cagaaaatat caaacttacc atatgtagcc ccaaatagct
    12901 atagagtgta cattttatga atattctttc atttataaaa aattatttta tttaggagga
    12961 aacaacaatg gaaaattttt ggaatccgct tacttgcttt actgtatgtg taatgattta
    13021 tgcttttagt gagtttttat ctaagaaaac aaaaggtgca atttcaacat tgctatttgt
    13081 atgtattata tttttaatag gattttggac aaatatttta cccaaagaca ttacaggagc
    13141 atcagggata ttagctgcaa tgagcaactt tggtatagct ttattaataa ctaacttagg
    13201 aacacttata aatcttgaag acttatgtca tgaatggaaa acggttgtaa ttgcattaat
    13261 aggtattgta ggaatagggg ttggctgttt aacagtaggt agtatgttat ttggtagaga
    13321 gtatgcttta atagcagctc ctccaatagc aggttctact gttgctggta ttatcgtaac
    13381 aactgttgca gaagctgcaa atagacctga acttgctgca tttgtaattc tagtattatc
    13441 atttcaaaag ttctttggca ttccgataac tacatattgt ataaataaag aattaaaatt
    13501 taaaagagat aatggggatt ttttgaaaga tgagtcaaaa agtaatttta aacttccaaa
    13561 catgagaatt tttaaagaag atttaggtaa aaaatcatct actttagtgt atcttgcaaa
    13621 gctttcattt gttgctatga ttggtaattt tgtaggattg gctactttaa taccaggatt
    13681 tacacctgca aactattatt taaatcccaa catagcatgt ttgttagtgg ggttgatttt
    13741 tacacgaata ggttttttag aaaaaggaat tttagataaa tctcaatcta atgggattat
    13801 aatgtttggt tgtatgttaa tgttacctgg aggacttgct aaggtaactc caacagcatt
    13861 gtttgggatg attgttccaa ctataggaat acttgttgta ggctccgtat ttataatatt
    13921 atttacttca attgtaggca aactattggg atattctcca agaatgtcag ctgcaattgg
    13981 tgtaacttgt atgcttgctt atccagcaac acagataatt tctaatgaag gtattgatgc
    14041 aatggaagga actgaagaag aaaaacaaag agcaacagat tatttgttac caaagatgat
    14101 tataggagga tttgttactg taaccattgc atcagtagca tttgctagta taataggtcc
    14161 aattatattt ggttgatagt aaatagaatt ataggaggaa taggaaatga taggaagtat
    14221 atctataaat gagatagata aaaaaagatt caaacttgat gatttgagta ggaaaatatg
    14281 ggaaaatcca gaaaaagcat ttaaagaatt taaagcatgt gaaaatacag caaatttttt
    14341 aagaagtgaa ggatttgatg tagaaatagg tgtaggaggt ttagccacgg ctattaaagc
    14401 tagttttggt tcaggcaaac cagttatagg ttttatggga gaatttgatg cgttacctgg
    14461 tttaaatcaa aaagtttcaa caaagcaaga agcatttgaa ttgggtgctt atggtcatgg
    14521 atgtggacat aatttattat gtacagcaca tgtaggtgca gtagtaggga ttaaaagaga
    14581 aatgatagaa aataacttag gtgggactat agtattttat gcatgtccag gagaagaaca
    14641 attaacaggt aaaggattta tggctagagg tggagctttt gaaggtttag acttagctat
    14701 aaattttcat ccaaataaaa ttagtgaagc tacaattggt acttcaacag ctgttaattc
    14761 tgtaaaattc cattttaagg gaaaaactgc acatgcaggc tcagaccctc aaaatggaag
    14821 aagtgcacta gatgctgtgg aacttactaa tgtaggagct aactatttga gagaacatgt
    14881 tacttctgat gtaagaatcc attatacaat tacagatgga ggagtagcac caaacatagt
    14941 tcctgataaa gcatcagtat ggtattacat aagggcttta agtagagaag ctgtagagag
    15001 tacatatgaa agacttgtaa aggtagcaaa aggagctaca atgatgactg aaactgaagt
    15061 tgaagtagag tttttaggag gatgttataa tactttaaat aatcatactt tagcaaatct
    15121 tgtatcagaa tgtatgaatg agattaaaca agagccttgg actcaagagg aattggattt
    15181 tgcagctgaa ttagatagac aaagcccaca acaatataag gatatgataa gtaaatataa
    15241 tttgcaagaa ggaactcatc tatattatgg tggaggaaat gttacaaact ttaatagtta
    15301 tggctctact gatattggag atgtaatgca tatagttcca acagcatact tttttacagg
    15361 gtgtacgaat ctaggtgcgc caggtcatag ctggcagttt acatcttgtg caggaagttc
    15421 tataggagaa aaaggtatga tatatgcagc aaaaattatg gctatgtttg gagctaaaat
    15481 attaaacaat ccagagatag ctaaaaaggc aaaagaagaa tttgataaat ctatgaatgg
    15541 taaaacatat aaatgtccta ttccagatga tattccaacg ccttaaaaag atatgaagtt
    15601 taatatataa aattataatt tttatgtcaa catcatttca tactaaaaga aagtgagatt
    15661 ttactaagag tttaggagta tttttatgga ttggaatggg aagtattagt cagggaaata
    15721 attttggtat gcataatcct aaggcaattt ttaatgaata gggattagtt tacggttcag
    15781 ctttatttgc taattatgca gtaaaatggt tagaaaataa ttttagtaga gaataacata
    15841 aaatattatt aaatatcata aaaggtatat cttaaaaaca aatgtcaaga tatacctttt
    15901 agagaattat atataatttt acttaatatc agatgataaa atatttttat gtattttgga
    15961 ttttaatatt tattttctga tataaataat ttgtataccc tttcaggtct accttttgtt
    16021 gagttttgtt tttcatataa tatagtagcg tttccagact ttaagagact acttagaaat
    16081 ctattagcag ttctcactgt tacatttaaa catgaagaca attctttagg agtaacttca
    16141 tctctttgta gaatttcagt aacagatata atcttttgaa tagtaagagt agacaattta
    16201 gaacttttag caattgtatt tatatgtgga gttactttat ttgaaacagt aagtaactta
    16261 tcacataata aaggtcctat tgtctcataa ttttcgttaa ctaagaaact gtagtttaaa
    16321 gggtttattt tagattcctt attagcactt atggcactag acatagcttg ttttatatca
    16381 ttacctattc catatccaat acatacctta atatttatac tattttcaat ggattctttt
    16441 atataacacg tagtaaaatt tttagttaat gatttaatcg tttcacattt agtgaaaatt
    16501 ttaaaagaat tactattttt ttcaattata aaatcggtta acttatcttt ttttatacta
    16561 tttaatattt tataaacttg gtctaaagta gaatcatcat aatttgtatc tttaactgtt
    16621 atatatatta cacttggttg atttcccttc attctatgta aatgaatgtc ttttattaag
    16681 ttattaaaag tattttttaa taaatctata tcaggatata tgaaatgaaa gtttactcct
    16741 gcatcttgta acataggaac aatactacta aaacgagtag tagaaaaatc aattttccct
    16801 tcattccata gattaatatg tttttttgca atcttttttt cgagttttgc tatatcagat
    16861 aaactcattt tagatgcatt ttcatcaata ctatccatta agtctccaaa tgtaccattt
    16921 gataaataat atgatatatc ttttggatta tctgcccagt cagttaagtc aaagtatgct
    16981 ctagaaaaat ctaatgtatt atatttaaag ataagcttta gaaacatatc atagtaactt
    17041 tgcaaatcag taccaaaatc aactagaggt tttttaatag ttccagcctt ttttgtaata
    17101 gcttttttgg ggataggtcc actaactgca aatccatcaa aactatcttc tatttctaaa
    17161 tacaaatctc caacatgaga aaaatctcta tagatatata tttcaatttc tgcattaata
    17221 tttaattttt ttatagaatt atctacaaac tcttttaaaa attcggttgt tatgactgct
    17281 attttcatca tagattactt ccttttcaat tattataatt attttatatt aaatattaca
    17341 ttaatctatt gcgctagtta aaatcatatt tcaattaaaa taaataactc tttataaaaa
    17401 acaattattt agatagaaaa atatttacga actttaatag tctttgttaa ctttgatttt
    17461 atttaagtta ttatagactc gctaatttta taattgtaga tttagctact ttatgttctt
    17521 ttattgttta tgttgttgat ttagaagtta ttttaagtac ttattttaat tgaagttgtt
    17581 tgttttttaa aatcctttgt gtaatcttta tttttctagc cataataaaa atatttgtat
    17641 ttgtatcact atatataata atatcatgac aaaatattta ttgtctaact aattataatc
    17701 tattcaaaat gaaaatggga atgagatatt attacaacaa gtcgtattat tattaaaatt
    17761 gattaaataa ttaaatgatt aaataattaa atgattaaat gattaagtga ctgttatata
    17821 acaatttgta attttattta acagccactt aggtatttaa gagcaatgga attgagtgta
    17881 tatcaaatta taataatttc ctagtaaata attgaaaaat aaggtaatcc atttttatat
    17941 ttgatatctg gcttaccttg aataagtgga tatagataat ccagtgcttc gtcagttata
    18001 taattacatt cttcatttat ccactcttta gggaaatact ttgtcttgtt agctatttta
    18061 gaaatatcag tatgaccaac ttcatactta taaggattat tgcatgttct attaatgata
    18121 gccataactc ctgtatattc ttttttagat agctctatcc catatgcacc aacgtcagct
    18181 gcttgtttta aatcagtacc tgaagctaaa tgcatagcac atctttgtat tacaccaagt
    18241 tctaaagttt ttactcttgt tgtaattgat gatgatacta taagattctt tagatagttg
    18301 ctcactccac ctaattgaga atgaccaaat ttatcgtgag cagaagtttt ttgttcgcat
    18361 ataaagttgc cgtatttatc tcttatacct tctgatgcaa ctatataagc cttatttttt
    18421 tctttaaata tttttctaac atcttctata aacttatctt catagaaatc aatttctgga
    18481 aggtatatta aatcaacaag tggagtatca ttaagtctag ctagtgaaga agaagctgct
    18541 aaccatccag tatctctacc catagtttct aatataaata tcccattatt tttatatata
    18601 gaaaaatcta agtacgtttc cattattagt gtagaaataa gctttgcagc agaaccaaat
    18661 ccaggacaat tgtcagttcc caataaatca ttatctatgg ttttaggaat ccctataaat
    18721 tttattttac aagtagtgtt tttgcagtat tgagaaaatt tcattactgt atccatagaa
    18781 tcatttccgc ctatgtaaaa taatgtatct atttcatatt catctagtat atttataact
    18841 ctatcataat cataagaatt tatcctataa tcagctaatt tgtatctaca agaaccaaga
    18901 ccagatgaag gtgtttgctt taaatttaat acattatctt tgtttaaaga gtctgaatct
    18961 attatatttt tatttaatat accttcaatc ccattgatac caaaatacac tttatcaaag
    19021 tatttagttt ctaaattttt ttcataaata ccaattgcag aagcattgat aacagctgta
    19081 ggacctccag attgggcaat aatacagttt ctcattttac atctcccttt cattaatatt
    19141 gttatgaatg atacttttta ttgagcaaat ttatatttat agtctgatta tatattaagt
    19201 gaactagcta tatcaattga gttggtatag ataataaata ccataagaat gtggcaaaaa
    19261 actaactttt tatatacaat taatgtctat aatttaccac aatataaagg tacttttaag
    19321 gagtagtcaa agtgttgtga aaagaaaaat atcagtgtaa tattaattta caaagcaaaa
    19381 taagttcaca gttcacaaaa gcagaataag ttcataaaag aaatacatac agcaataaaa
    19441 gtaatactaa attaaaaaaa ttaaaaaata tcaaaaacta atatttaata ttaattaaag
    19501 taaaatatgg agggacacaa atatgaaaca cataaaaata gcagcaggat tggcacatgt
    19561 aaattatggt catatatcag ccgtagttaa ggaagcaatg gatgcagggg tagactatgt
    19621 acattcagat gcagcagata tgcatgactt aaaaaatatg caacttatgg gtggtcatca
    19681 aataatagaa gcaataagac cagtgacaga taaaccaata gaatgtcata tatacacaag
    19741 agattgtgat agattattta tagaaaaaat agcagcagca ggatgtaact tgttgataat
    19801 accagctgaa catttcttag gggctcctct tgcatacata ataaattact gtagagaatt
    19861 tggtatgaaa gtaggattga cagttggatg ttatacacca ctatgttttg ttgatgaagc
    19921 tatatatgat atagacagat tgcaaatagt tgttcatggt gttgatgaaa ctgatggaaa
    19981 agataactgg ggatggagaa agagtgctgt tgacttagta aaaagagcta gaaaaatgat
    20041 agacgaaaag aatcctaagt gtgaattagc aatagatggt ggactaagag cagacaatat
    20101 ggagccattg atagaatgta atccagacgt tgtaatatta tcttcagcaa tattcaaaga
    20161 taaagatggt atagcagcag gtgttaagaa ttgtagaaaa gctatagatg aagcagctac
    20221 aaagtttggt ttagaataag ataataaact atgataaaag agatgctttc ttaatgtttt
    20281 aaggaagcat taattttatg aaaaactaca ggaagttaga ctaatttaat tgatttttta
    20341 tactgaaaga atataatcat tggaggttat taaatgaaaa aagaaatgat aaaggattat
    20401 ttactgataa cagtatcagc atttttaatg gcattagcag ttaatttttt ctttgcagaa
    20461 catacattag ccccaggagg gataacagga ttatcagtgg tacttagtac atttttatca
    20521 atgcctgttg agaatatatc attaggaata tctatgccac ttttagtaat gggattatta
    20581 tttttaggga aaggttttgg aataaaaaca ttatatataa ctcttatggg tccattcttc
    20641 ttaaaagtaa taccacaaac tcacataact gacaacctat tagtagcagg agtgataggt
    20701 gggttattgg taggaactgc tataggtata gcaataataa gaggttgtag tactggtgga
    20761 actgatttag ttgcaatgct tattaataaa gtaattaagt ttctgaagtt gccagttata
    20821 ttatttatgc tagatggatt tataatagta gcgtctggaa taataagtaa gaattttatg
    20881 atatctatat attcattgat atctttatta cttataataa aaacaatagg atttgtaact
    20941 acaaagtttg gtaagaatac tgaagaaatt aataatataa atagtacttg cactcaataa
    21001 aaataataaa acttacttta aatataaaag tttaaataag aagtttaaat gtaaaaatgg
    21061 aggtgtctca aaataaattt tttagttcac gaggcacttt ttttctatga aatcaaatat
    21121 atttttatca tgtagacaat gaaaactagg cttatcttta tgttgagaca agcctagttt
    21181 tgtttattta taggataata ttttattttt ttcagaatac aattttttta taattgtact
    21241 aagtctggaa atatcattct tgcttaaaag agcatttata tttatcagtt cagcattatg
    21301 ttcaaagtcc acaggagcag tggttagtat taagtccaca tcatcaaagt tcgtaaatga
    21361 aatagaagat agaggtatag atttaactat attaatctga ttaaattcaa aacttagttt
    21421 ttggactaat aagttagata caccatcact acaatgacat attaaaatag tatttagagg
    21481 agatttactt ctatctattg ctgatatcaa atataaagca agatacccta tttcgtcatc
    21541 attaacttca taattcatca actgtttaat aacagtatta gattctttag cagccttata
    21601 tgtataaggg aatgtcctct ttatatcatt taatatggga tttgtaatag taaatccata
    21661 gtttattctg tgtagaactg atttaaggtg attagcaaga gactttatta atattaaatc
    21721 atcttttaag tttaaattta gtatatttcc ccaatgaaca gctattgctt cagatagatt
    21781 atactctgta atttcttcat ttttaagagg ttcaagagta gtagttttct ttattgattt
    21841 gagcaatcct tctacatgaa gaaggatata acagacctct tcactaataa attctacatc
    21901 aaaagcttca cctaggttag aacataaaat ttttgatttt tcaaagtatt catgttccaa
    21961 taattctcta aagaaacctt cagataagtt aatatatctt ttaattgaaa tcctcctaat
    22021 acatatagct atatgtatta agaaatttat ataatactca tcactaaggt tacttttttc
    22081 tacttgcaaa gtttgtagag ttatttgaga taacttctca aaatcatagt taaataactc
    22141 cttaaatatt tttgttgatg gagtatcttt acattcatta gattttgaga ataatatttc
    22201 tttaagctca gtataacttt tattaacagt agcaagctca aaaattgctt ttcgaatatc
    22261 tttctctttt ccctctaaat atactccatt attggttttt ctaactaatg ttactttaaa
    22321 gttttgtaaa aaattttgaa taactaccaa gtctttatgc acagtagctc tgctaacatg
    22381 tagttcattg caaatatcac gaatcctaaa cttagaattt ttaataaata atttacttag
    22441 aatatacctt tttctatctt caggagaata tgcatatata caatttgatt tatcattgat
    22501 atctctaata actttaagtt ttatatcttc attacctaga ataataactc ctgaaccagt
    22561 ttttttatcc agggataaat taaactctaa aagccattca tctaaaataa caaggtcatt
    22621 acgaatagtt ttattactaa catttaattt ttcggcaata gtatctacag taatatagtc
    22681 tgagctgttg agtaataatt cagcaatatc taataatctt ttgttcaatg caaaccctcc
    22741 taaatcttag ttactattta ttaaccttgg accaatctct ttcaaaagta ttggcaccat
    22801 ctactgtaag ctggttaaaa gaagcttttt taaataaatc atatgttaca gctgcataat
    22861 cacatccaca aagagatgct tgagttaaat ggaatacatt ttttatagaa gctgcaacaa
    22921 ctttagtatt atatccattt attgatataa ggtcacatat ttctgtaagg ttttttatac
    22981 catcattccc attttcatca tttctaccta taaaagggaa taggtaatca gcacctgcat
    23041 ttatagctaa tgatgcttga tttacattga aaatcaatgt acatgcagtt tttacacctt
    23101 tactatttaa tatgtttata agttctaagc caatttcaga gaaatttatt tttattatag
    23161 tgtctttatt tatatttaat atcttatcac atgaattaat taattcgtat aaattatttc
    23221 cgattacttc agcagttaat atttctggat ttagattagt acatgtctca ataaactcat
    23281 agaagtttat attttcttta agatacatag atggattagc tgttattccc ttaaatccac
    23341 actttaaaca cttttgaatt tcatcaagat tagcactgtc tatcaaatat ttcataattt
    23401 aattctcctt taagcttatt tgtcataaaa aagtgtatat actctatttt tattattaag
    23461 tcaattatac aataagattg attataaaat tataacatgg gtacttaata aaatttacat
    23521 aatgatatgg taataataaa acattgattg tctaataatt gccataagct ttagtaaata
    23581 agagttaaca gtgaaggtat tgccttaaaa atcctatgat atgtataatt tgaatatgaa
    23641 ggcaataatt taagggagga aaaatatgat taacttttat caaccatcaa gaataaattt
    23701 tggacaagga actataagtg agttacctag aataatagga aaatatggaa agaaatgttt
    23761 gttagttact actccaaatg tagagccatt agacaagcta tataaaagag ttacattgga
    23821 tttaatagaa aaaggtatag aagttgtaca ctttgataga gtagagccaa acccaactgt
    23881 agaattaata aatgaagggt ttgaattagc taaaaaagaa tctgtagatg ttgttttagc
    23941 tgttggtgga ggttcaagta tagatactgc aaaagtatta gcattgactt ttggtttaga
    24001 aaaaatagat tgggattata tgtttagtac atatacaaat ccatttaaaa tatacgataa
    24061 ggtaagtgaa aaagaattac cattaatagc tgtatcaact acttctggaa caggaagcca
    24121 agttacacaa gcagcagtaa tatcgagagg aagcgagaaa aatacaatat ttcatcaaaa
    24181 ttgtttctca aaagaatgta tagttgaccc agagcttatg ctaactcttc cagagagaat
    24241 tactgcatca acagcatttg atgcctttac tcatgcgttt gaaagttata taaatccaaa
    24301 tgctaatgac tttacagaga taatgtctga aaagtctatg gaattagtca ttaactattt
    24361 acctaaagta atggaagata aaaataatat agaatacaga acaaagttag cagtagcaga
    24421 tacattaggc ggaagttcac tggcaaatgc tggagcagca gcaccgcatc cactaagtga
    24481 aataatagga ggagttacac atattcctca tggcgaggct ttagctatag tgtttccaaa
    24541 atttgcagaa aagttctata aagataatgt agataaattt gctaaagtag cgagaatgtt
    24601 aaaccaagaa ttggaaaaag tggaagataa tgaagcagct aaaactttag gaaaagaaat
    24661 agaacgtttt ttaaagaatg tgggacttaa gacaaaaatg tctgagttta atgtcacaaa
    24721 agaacaatta gaacaaataa cgagttgtcc agttttagga tttttacctt ttggaaagaa
    24781 ggaagacctt gttgaaatat tagaaaaatc ttattaggat gtgatacaaa tgcgatataa
    24841 attaatttgt accgatatgg atggtacttt gatgggtaaa ggatttgaag tatcagaaga
    24901 aaatattaaa gcattaaagg aagctatgga aaagggcatt aaggtagcct tagtcacggg
    24961 aagaccttat aatgctataa aatattttac aagtgtttta ggagatgata tatatattat
    25021 atcaactaat gggacatatt ttaaattact gggatacgag tataagaagg ttttgagtaa
    25081 agaagctcta aagaaaatat atacaatagg tgaaaaatat aatttaaata aacattttaa
    25141 aggttgtaaa atagttatat ccaacaatga aataggtcaa gaacatccat atagattaat
    25201 aaatagtaaa aataaagaag aagacagaat tgaaataata gaaaatgcaa gttgtgaaac
    25261 tttattagaa aaagctgata atgagatttt aaaatgtata cttttctcag aaaacgtaga
    25321 gtctttaaga gaagcaaaag aagaatttaa aaaacaagaa gatttagaag tagtaagttc
    25381 tggaaagata aattttgaag ttatgagtaa aggtacttca aaaggtattg cagttaaaaa
    25441 attttgtgat atattaggta tagatagcaa agaagttatc tgtataggtg ataatgaaaa
    25501 tgatatatcc atgattgaat ttgcaggtct tggtattgct atggggaatg ctacagatga
    25561 agtaaaatct atagcagact ttgtaactga tactaatgta aatgatggtg tagcaaaagc
    25621 tttaagaaaa gtattatcat aaaattttat aatgtggaga gtgtgttatg tttaatatat
    25681 ttaagaaaaa agaaaataag gttgagaaaa tatacagccc ttttaaggga aatttagtta
    25741 acttagaaga tgttccagat gcagtttttg cacaaaagat gatgggagat ggagtagcaa
    25801 taataccaag tgaaggtaag ttatattctc ctgttgatgg tgaaatagtc agtgtgtttg
    25861 atacaaagca tgcaataacg attaagagta atgataacac aaatatgttg atacatgtag
    25921 gtttagagac aatgtcacta gaaggaaagc cgtttgatgt taaggtaaag gcaggagata
    25981 aggtaaaagc taaagattta ataatggaag tagatttaga ttttataacg tcaaatgatt
    26041 taaatataat aactcctgta gttataatgg atgatgctga ttctgttaag agaacagtaa
    26101 aagataggat agaacctgga aatgtagata ttaatagcat aataatggaa gttgaataga
    26161 tataaaaagg gagttgtctc aaaatttatt ttactaatca aattttaagt tcaacttcct
    26221 ttttggatgt gtttttttga tattcttttt ttcttttgca ttatttatat acaaactcaa
    26281 ttttcatttc ttagattctt caaaaagtaa atctattatt tatttcatca tattctacaa
    26341 aagtatttca taacaagtta gagcaatttc atgaaaatat catcattata atgaaaaaaa
    26401 gaaaatgttg atacagatag tatcttttgt tgttttttga ataaaacaga aattttaaag
    26461 tgaactttaa gactattctt attcagaaag tgatcttcat aaaaatgtat ttttataaat
    26521 ttatgttgtc tgtaataatt taattattta taattaaaag ttgttatttc tatgaataaa
    26581 ttactttata tttaatcaaa tgttataata caattaaaat gtattaatat ccaataacag
    26641 ttagggggat tctaatgatt aatattgcta tatgtgaaga taattttgtt gatagaggta
    26701 tattaaatga ctacttaatt agaataatga atgaaaactc atataatata agtttattca
    26761 aaagtggaga agagttactt gataattatc cagatgactt agatatatta ttattagata
    26821 ttctgatgaa aaaaataaat ggaatagata cagcaaaaaa aataagagaa tttgatagta
    26881 atgttgaaat tatatttata acatcattat tagaatatgc gttacagggg tatgaagtaa
    26941 aagcttttag atatatatta aaaccaattg aatatgaaca actgtcaatt aatatcatac
    27001 aatgtttaga tgatattaat aataaagcaa gtaagtttgt atatataaaa tgtaatagcg
    27061 acatagtaaa gatagatatt gagtcaattt tatatatcga aaaaatatca agatatattt
    27121 ttgtatatac tgaagatcaa gtatataaat ctaaaatgaa tttaaaggac atagagaaaa
    27181 aattgcaaca ttataaattt tatagatgtc atttaggtta tttagtaaat gtaaacaaaa
    27241 tagattgttt aggctcaagt gaagtaagta tatataatca tagtattcca gtaagtaggg
    27301 gaaagaggaa gatattaaaa gagtttataa ttgattcgaa agaaaagagt ttataattat
    27361 gtatttgtat gagatatgga ttattataaa cttcatttca ttgatagtag actttttaat
    27421 tattaataaa atttttactt atcttagcaa gaagaaaaca tctagaaact ttatgtttat
    27481 cagctttctt attgttataa ttatcttatt ttttttaaat tcaaattcta ataatgaacc
    27541 catgatatat atttttttta gcataatttt gtattatata aactatgaaa ctagtttagt
    27601 taaatcaata atagtaccat cattatattg gataatatat cttttcttaa ttaaatatat
    27661 ttcttctgtt ttagttatta atattaacta cacagaacag caagtattaa aaggtgatat
    27721 atttgcatta gagatgatgc tattagcata tattttctta atttttttag tgtttataat
    27781 aaaatttgtt gttacaaaaa ataattttat aaaaaatata catttaatat tttttacatt
    27841 tataaatata gtgagttttt tattaatatt tagaggtgca gccaaagata taaatgtaaa
    27901 ttttgtagat aatatattca taataattat aggttttaca attgtgatat ttaatttata
    27961 tttattatca atgatggata aacttctaga aagtagacga attgaaatag aaaataaatt
    28021 tatgaaagaa aaaatagaaa ttgaatataa gtatataaaa aaactgcaat atagcaatga
    28081 aaatataagg attttaaagc atgatattaa aaatcacctt atttgtataa ggaatataca
    28141 taataataaa gaagcatttg ataaatattt ggatagtgtc gatattgaag ttaataaaat
    28201 aaatgatata tatgacactg gtagtataat tgtagatgct atattggatg aaaagaaaat
    28261 tatatgtgac aattataata taaagttata tgtaaaggca aattttacag gatgtgattt
    28321 cattagtgca tttgatttat gtacaataat gtcaaaccta ttagataatg caatagaatc
    28381 aaatcttaaa gtaaaaaatt cagattgtag aaatataact gtaaaagcaa attgtgaaaa
    28441 atatatgctg ataataatag tcgaaaataa taagtctaat aaaataatta aatctaaaca
    28501 gagtataatt actgataaaa aaaataaaac tattcatgga ttaggattaa aaagtgtcaa
    28561 aaagtctatt agtaaatata atggagattt atttgtggaa tataatgatg aaaattttaa
    28621 agttaaaata ataataccaa caaatatatg acgagttatg cacgaaaaat gacaatctat
    28681 gtacaatatg ttgataaagt aagatgcata aactactatg taattacaaa ggggggtaat
    28741 aaatatgata aaaataaaaa aaataacaga taaggaaaag gttgttgttt cagctcaagc
    28801 aaaaaaacca tgttcatgtg caggtcaagt attaaagtat ccacctgtaa gtaattcttg
    28861 tttatatgat tatgatgact ataatcaacc tagatggtat gaggcacaat gtcaataagt
    28921 aatactaaag ccacttttat aatataaagg tggctttatc tataaaatat gtctttattg
    28981 ggaggagaat atgaattata aatttgatga tagtgtaaaa cttttaaaaa atggagaata
    29041 tgtaattctt ggtaatacaa agaatggtca atggattaaa atgacaaatt atatttataa
    29101 tatatttaaa ataggaatag ataactcttt agatataaat gaattaaaaa aatgtttaga
    29161 agatgatgaa gatagacaat ttatacaaaa tctttatgag aatctattag acatgagaat
    29221 aatatatgat gaaattaata atgtagcttt tcaaaataag atagcctctc ttgaaataac
    29281 aaatagatgt aaccttaaat gtgttcattg ttgtgtagat gcggataatc ttataagtga
    29341 aaaagaagag ctgtctacaa tagaacttaa ggatgcaata aaaaaaatag ttgaatggaa
    29401 tcctatgaat attatgttaa gtggtggaga acccatggta agaagtgatt tttttgagat
    29461 actaacatac ttgaagtcta tatataaagg aaacataata gtttcaacaa atgcgactct
    29521 aataaataaa aataatgtag agttattaat aaaaaatgtg aataagctag aaattagctt
    29581 agatggagta aatgaacaaa cttgcagtat agtaagggga aaaggtgtat ttaaaaaggt
    29641 aattgatagt gttaatctta taaagagctt tggtttcgat aatataacac tatcaatggc
    29701 tgtaggtaat aaaaatgaat atttagaaga agaatttaaa gatctatgca aaaacttggg
    29761 agtagggcat atgataaggc gatttggtcc agtaggaaga ggaaaagaaa atgaacattt
    29821 atttttagat aataacaaag atgaagctta tatacctgaa aattttttaa aggataatta
    29881 tgatggaaat atgggtgtaa catcttgtaa agcaggtatt tatgaaatat ttattagaca
    29941 caatggagat atatatcctt gtccatcatt tatgtcagat gaatataaaa ttacaaattt
    30001 atgcgatata caacaaataa gtgagattaa agataaatat ataaataaag tggatgtatt
    30061 ttctatatta gaaaaaataa atccagaaat ttataaaaat tgtatagatt gtaatgtaaa
    30121 tttattttgt tggacttgtc caggagaaat tgaagaacta aaagatagta aagcaagttt
    30181 atttaataag tgtagtaaaa taaaaaatat tttatataaa agagtgtggg ggaatgatgg
    30241 agtatgttag caacattttg gattacaaat gaatgcaaca tgaaatgcag atattgctat
    30301 gaaggtaata ataagaataa taaagttatg tctaaaacgt tgatagataa atcaataagt
    30361 tatgtattaa atcaatctaa tagtttggat gatgatgaac ttgtaataca aattcatggt
    30421 ggagaaccat ttttagaatt taacttgata aaatacataa taagtgagtt taaaagcgaa
    30481 aaatttaata aaaatataat attttcaaca actacaaatg gaatgctctt gaataatgat
    30541 attttagatt ttatacaatt atatattgca gaattaacca taagcataga cggtgctaaa
    30601 aatacacatg ataaaaatag acaaagtata aatggaaaag gtacacatga tatagttata
    30661 gaaaatagta gaaaaatttt aaaaataaaa ccaaatgtaa gagtaagaat gacatttgat
    30721 acagagacag taggtaattt atctaatgat ataaaatatt taataagcga aggatttaga
    30781 acgattgttc cagttccaga tatgtttgag actagatgga acaataatca tatagaggtt
    30841 ttgaaaaatc aaatatacca aataaaagag attataggta acagtaaaga tattcttgta
    30901 agcctcacag acacaaacat atataagtat aaaggtgttt gctctggagg aaagttaagc
    30961 tttaatatat gtccagatgg atatatatat ccatgcacat tagcagttgg aaataaagat
    31021 tttagtatag gaaacatata tgatggtata gataaaacta gtagagacaa gtttttgagt
    31081 aaatcatacc tagataataa cgattgtaaa gggtgtgact taagcaattc atgtgatgga
    31141 aatagatgta agataataaa taaattaact agaggttcgt attttttacc atcgccaata
    31201 aattgtgcta tacaaaatat aaaacatgag ataaatataa gtaaagaaat tgtattatag
    31261 ttttgtagag ttaaggagga atagcttgaa acgaattaag gttgcattaa ttgactcagg
    31321 tatagatatt aatcataaat atttaaagaa taatatattg tatggcaaat catatattta
    31381 taaagataat aaaatagttg tctcaaatga aattgaagat attaatggac atggtacatc
    31441 atgtgcatca attataaaaa gcgaatatga atatgttgat tttataataa ttaaaatatt
    31501 tgatagagat ggattaacaa atatcaaagt actagaagaa tcattaaatt acttaataag
    31561 tattgatgta aaaattataa acttgagttt agcaatacat ggagacatta attcttgtaa
    31621 agacttatat aaaatatgtg aaaaactaaa gaatcaaaat aaaattatag tttcttccct
    31681 tgcaaattat aattatatag aagagagcta tccatctata tttgataatg taataggagt
    31741 aaaaggaaat ttattaaaaa aaagatcatc attttggtat aattcagaat ataaatatca
    31801 atgtgttgta gacgatagtg atagaatagt tgcagattta ggtaacagtt ttaagttagt
    31861 tgaaaaaagc aacagttttt cggctgctaa aatgagtgga aaaatagcta agataatagc
    31921 aaataaagtg gatataagtt ttgatggatt aagtagaata ctagaagaat tgtctgagtg
    31981 tacaaattgg aaagacgaag atctatatac taataagaga agaatagatt acaaacagta
    32041 tttatatgaa aacaataata taaatcttaa ccgagtatta aaagtgttgg ttgataatct
    32101 taatattggg tgtaatgtgg atattttatt tgatagtata ttatttagta aatatatagg
    32161 tctaaaaaat aataattgta ttgaaatcct aaagaaacta gagaatgaat ttaatataaa
    32221 gattgattac acaaaagtat ataaagaaga tctaatatca atatatactt taactaattt
    32281 gattgaaaag gagagtatat gtgaacattt tagaaactgt aaatatctcc aaaagctata
    32341 gtataggcga taaaaaatca tatatattaa aagatataaa tataaaaata aaagaaggag
    32401 aatttatatc tataataggt cctagtggaa gtggaaagtc aactttactt cacatattag
    32461 ggggattaga aaatcctact actggtattg taaaaattat aggaaaaagt atatatgatt
    32521 tatctgagat taaattggca gaatatagaa gaagaaggtt tggatttata tttcaacaat
    32581 ttaatctaat accagtactt aatgtaagag aaaatattga aatgccatta atgctagata
    32641 gagctaaaat tgataatagg ttcataaaag aaataattga gtttttaggt ttagaagaaa
    32701 aagaaaatta ctatccgaat caattatctg gagggcaaca acaaagagta gctatagcta
    32761 gagctttagt aagtaagcca gatattattt ttgcagatga gcctactgga aacctagaca
    32821 ctaaaaatag tgatgaggtt ataaaacttt taatgaagtc tatacacaag tataatcaga
    32881 ctgtattatt aattactcat gattataaaa ttgctaaaaa cacagataga acaattaaaa
    32941 tactagatgg gaaactagaa ttataaatga tacaatgtca agagggtaat aaattgaaaa
    33001 atactattaa tatgaaaaag tttctatatc tcataattca aggtaataaa aagctagtaa
    33061 ttatatcttt tcttatgatg atagtagtag caatgataga tttgtatata cctcaaataa
    33121 taaggaatat attggatata gctataaaat caaaaaatat tactatgcta ataaaactaa
    33181 tattacaatt tatattaatt aacataatat tatctaatct agaactattt ctggaatata
    33241 attattctaa aatgaagaag aaaataacta caaaattgaa gttaaaatta ttgagacatt
    33301 tatcaaagtt agacggacgt tttttctctg aaataaaaac aggaaatatt atgaacatag
    33361 tagagtatga tgtaatgatg ttagacagat ttggaataga attaatattt tcattaattg
    33421 tggacataat aactgcattt atatcgttgt attttttaat aaagatacaa tcaaaacttt
    33481 tagtaatagt tgtagtaatt caaattgtaa tttcttttac tcaatatata tttacaaaga
    33541 tgatttctaa gtatacacag aatataagaa gtaatgctgg aagtatatct aatatagtac
    33601 aagaatacat atctaatatc atgaatgttg ttatacataa aggtgaactt aattttttta
    33661 cgcaatttct atcaatgcaa aagaattttg taagtaaatg cataaagcta gatatgatta
    33721 tggctggaaa tgtttcttta tctaagatat taaacagttt aattgttatt tctatatatg
    33781 gttatggtgg atataaaatt ataaatggag aaattacgtt tggagaattg gtagcttttc
    33841 aacaatatac aggtatgctt attggccctt gtatgaatat aataaaatct aatgctattg
    33901 tacaacaatc attagtatct attaatagaa tatttgattt attaaatgaa gaggttaata
    33961 tgaagcaaga aaatacaggt gaaatatttc agagtgggat aactaaaaaa attagaatgg
    34021 atatgataga tgtaagtttt tcatatgata aagaagacgt attacataat ataaatatgt
    34081 cactggagag tggtaatatc tatggaattg ttggaggaag tggttcagga aaaagtactt
    34141 taattaaact aatatataga ttatgggata ttgaaagcgg aagtataaga attaatgatg
    34201 tagatataag agattataat ttgaaaaatt taagaaaaaa tattactatt atcacacaag
    34261 aaccattatt attgaatgat actgttttta ataatataat tttaagcaac aagaatatta
    34321 actatgagct agtagtaaga atatgcaagg aattagatat atatgatttt atagtaagtt
    34381 tacccaatga atttaataca attgtaggag aaaatggtgt aaaattgtct ggtgggcaaa
    34441 aacaaagaat ttccatagct agagcaatgt tgagtaattc aagtattcta gttcttgatg
    34501 aggctacatc tgctcttgat aatatatctc aaaaagattt attaaaaagt atgaaaaagt
    34561 tcttaaataa taaaatagtt ataataatag ctcatagact atctactata aaagattcag
    34621 ataaaatatt tgtaattaat aatggtgaaa taattgaatc tggaagtcat aaagatttag
    34681 tgtctcaaaa tggatattat tgtaatttac ttgaagataa aaaagaatat agttactgtt
    34741 gatgattaga tagtcaataa aaattctatt tttatattag aatatattga ctattttttt
    34801 gtattataaa tacaatgtat gaatgaataa gtacaaggta tgtaacattt attgatatat
    34861 atttattaaa atgatacatt tatttcagta attacataaa ggaggaattt tatgagacta
    34921 tctctagcat atgtaaaaaa atactttgga aggtcaatat ctatagcttt aagcataatc
    34981 attagtatct cacttataat tacagttgga atacttacta aaaatactca aaaagcaagt
    35041 gttgatagaa taaagtatga atctggagat taccatgtta aagttaagaa tattagtgga
    35101 aatgtaatat cggattataa aaagcaattt gatataagta tgatgggtgt atcatcttat
    35161 tacgattcaa gtgaatttaa tggaaaatta atgttaaatt taattaaatc taatgaagac
    35221 tatataaaaa tttataattc aaaaattcta aatggaagat ttccaactag tgacaatgaa
    35281 gttgctttag aagaatgggt tatgttgaat ttaggtctaa aattagatat aaatcaaaat
    35341 ataaaaataa aattatataa tagcaaagag actaaaaatt ataaggtagt aggtatacta
    35401 aaagatagac catattacaa atctatagga atggcggaac taatacttcc ttttacagaa
    35461 aatataatca aagaaacgaa tctagaagct caaataagat ttaaaaaaga tatatataga
    35521 aacttatcaa aactaatgaa tgataatcat ataagtagaa aaaatgtatc tgaaaataga
    35581 atactattag atgccttagg agaaagtaat ggactaaatt acgattttat atttacatgc
    35641 attatatcaa tgattgtatc tggagtagta atttattcta tatttagaat atcaataatt
    35701 caaagaattt cggaatatgg aattattaga gccttaggag caaatatatt caatgtattt
    35761 aatataatat ttgtagagct ttttgcaatt tctttagtat ctattccaat tggagttttg
    35821 ataggtatta taagttctaa atatataacc ttatttatgg gaaatttact tattggcaat
    35881 atagtaaaaa taaataatgt agaaataaat ttagatgtag tgatgatatc tataataaca
    35941 gtacttgtaa atatattaat tataagtttt ttaacatgta caaatgtaaa taaaatatca
    36001 cctataaaat gtataaagaa agatatatct aaaaaaaatt ctagagaatc aagtatatta
    36061 aatactagga gattactgaa tcttttaccc atagaatata taatatcctt aaaaaatatt
    36121 ttaaaaaata aaaaaaattt tgtgattata gtattgtcta tgagtggagg gtgtattata
    36181 tttatattga ctaattttac aaacatattg gatgaaagac aactagaata tacatctaaa
    36241 gttgcaacag aaaattcaga ctataatata agctttgcac ctgttactcc attgaatata
    36301 ggtatatctg aagaaaattt aaaacaaatt agacaactag aaggcattga aaatgttaaa
    36361 acatctcaag ttatgtattc aagaatgata ttaaataaag ataatataaa taatatgaat
    36421 tattttgaaa aagtaaataa gtctgcttat aataagaagg ctttaaatgg attattagtt
    36481 aaaaaagata acgagtatat attaaagagc aatctatatg gttatgataa ttcatcaata
    36541 gatgctcaaa aatcctttgt tatttcagga gatatagatt tagataaaat gaataatgga
    36601 aatgtggcaa tactttatat gccggatcct agtttattta caaacattaa agattctcga
    36661 ccagttctta atttaaaggt aggagatatt gtaaaattga ggtttagaag tgattatgta
    36721 tcagatgaaa attttgcaaa attgaaagat aaaggagaat atgttgagga agaatttaaa
    36781 ataggtgcaa tagttagtaa tattttaaat gtagatggtt attatgcagg tatggacagt
    36841 gcgtctataa taatatctca aaatcaattt aaaaatattg taggtataca tagttataga
    36901 atgttagata taaaaaaaat accaacagtt gacaatatag agcttggaaa aaacataatt
    36961 gacatatcta gtaaaattca aggttcgata gttagagact ttacacaaga gataaaaaat
    37021 ataaaaatta tagaagataa taaaaaaatt cttatataca caataatatt agtccttttt
    37081 acaattagtt ttataaatat aataaataat ataaattata acttatactc tagaataaat
    37141 gagtttggtg taataagagc tattggattg gataataata gttttagaaa gatgctatta
    37201 tttgaaggtg ttgtttatgg acttatatct gctagtgtgt ctattacctt tggaatttta
    37261 ggtcaatcta tactctacaa tattttaaaa ggtaatttaa tgaatgccaa atttataata
    37321 gattataaat catacatatt ggtaataatt ttaactatta ttctgggagt agtggcaaca
    37381 tatttaccat ctaaaaaagt taagaaatta tctattattg aatctataaa tattattgaa
    37441 taaaatcata agtaaaatac atttatgctg tgtaaatagt aattactagg aaataatata
    37501 aaaaataaat aaaaa
//
LOCUS       DBGJFK010000033        36974 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.033, whole genome shotgun sequence.
ACCESSION   DBGJFK010000033 DBGJFK010000000
VERSION     DBGJFK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.033"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(210..1460)
                     /locus_tag="ACOIAP_001954"
     CDS             complement(210..1460)
                     /locus_tag="ACOIAP_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 family protein"
                     /protein_id="HGZ2638837.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMNNNEPLYDFITDDKIEHTVWKIDNDDIICNLVDEFRKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLCDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1492..2433)
                     /locus_tag="ACOIAP_001955"
     CDS             complement(1492..2433)
                     /locus_tag="ACOIAP_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HGZ2638838.1"
                     /translation="MYNILVTDGIEKEAAKKLRELNFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLEKADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2673..3749)
                     /locus_tag="ACOIAP_001956"
     CDS             complement(2673..3749)
                     /locus_tag="ACOIAP_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HGZ2638839.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASVLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYKDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4122..4637)
                     /locus_tag="ACOIAP_001957"
     CDS             complement(4122..4637)
                     /locus_tag="ACOIAP_001957"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGZ2638840.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDVAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5000..6070)
                     /gene="leuB"
                     /locus_tag="ACOIAP_001958"
     CDS             complement(5000..6070)
                     /gene="leuB"
                     /locus_tag="ACOIAP_001958"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HGZ2638841.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVEVCRKNEAVLLGAVGGPKWDKCKGDTRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVDKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     ETYNENEIRRIGKRAFEIARNRSKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVREPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLRDDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEYAVQSILNKGYRTID
                     IHNGVGTVVGTKEMGELIVNEI"
     gene            complement(6077..6568)
                     /gene="leuD"
                     /locus_tag="ACOIAP_001959"
     CDS             complement(6077..6568)
                     /gene="leuD"
                     /locus_tag="ACOIAP_001959"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGZ2638842.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIEEGDKIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6583..7860)
                     /gene="leuC"
                     /locus_tag="ACOIAP_001960"
     CDS             complement(6583..7860)
                     /gene="leuC"
                     /locus_tag="ACOIAP_001960"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HGZ2638843.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDIVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGKIGVDGALYKSMEFCGEGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTIEYINSHKCTTITKDVNVYQADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILASGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7817..9559)
                     /gene="leuA"
                     /locus_tag="ACOIAP_001961"
     CDS             complement(7817..9559)
                     /gene="leuA"
                     /locus_tag="ACOIAP_001961"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HGZ2638844.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESVKGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMSTPNI
                     YADQIEWFCENVSCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIREIYEDCTKLIVHDRHPYVGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKIESDRIGEELSSEAIFNLFRKEYIDVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARVSYMGNEQRIVGVGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEVK
                     NGDDYDAENLSQTC"
     misc_binding    complement(9683..9929)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10077..10523)
                     /locus_tag="ACOIAP_001962"
     CDS             complement(10077..10523)
                     /locus_tag="ACOIAP_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638845.1"
                     /translation="MSKNKFIYMNYYDNGYFKRGMAIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLSALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10544..11263)
                     /locus_tag="ACOIAP_001963"
     CDS             complement(10544..11263)
                     /locus_tag="ACOIAP_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HGZ2638846.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASNKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYHGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGVRVILGTDSHICYSIGKFENAEKVLKSVDF
                     PDELVINYHEDEIIGFFDINF"
     gene            complement(11381..12655)
                     /locus_tag="ACOIAP_001964"
     CDS             complement(11381..12655)
                     /locus_tag="ACOIAP_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGZ2638847.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDIRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RVKAAKEELFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12855..14222)
                     /locus_tag="ACOIAP_001965"
     CDS             complement(12855..14222)
                     /locus_tag="ACOIAP_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2638848.1"
                     /translation="MENSSTNLGNESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIIMACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWIFGASESTIGYSMDYLNIYLMGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIVLPVLGLGISPFIMQSTESLVLISLNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCLTYSTILWL
                     LLMIFPTFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIEE"
     gene            complement(14472..14909)
                     /locus_tag="ACOIAP_001966"
     CDS             complement(14472..14909)
                     /locus_tag="ACOIAP_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="COG2426 family protein"
                     /protein_id="HGZ2638849.1"
                     /translation="MGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVYVFSVIGSTL
                     VSIPLILTFRHILQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGIILFVGIPLPT
                     TGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14941..15570)
                     /locus_tag="ACOIAP_001967"
     CDS             complement(14941..15570)
                     /locus_tag="ACOIAP_001967"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2638850.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMVPLKKAKEAIFYPIVDFSEEDLKSFFDDCIMKKINESIKKVIYKNKEGY
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKNGEVIEQINS"
     gene            complement(15604..16491)
                     /locus_tag="ACOIAP_001968"
     CDS             complement(15604..16491)
                     /locus_tag="ACOIAP_001968"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HGZ2638851.1"
                     /translation="MKQTNTNIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLLLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSAYILF
                     VVLSLISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRGDAVEHRKILEDYDVENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNESNPTDIILTDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16520..17740)
                     /locus_tag="ACOIAP_001969"
     CDS             complement(16520..17740)
                     /locus_tag="ACOIAP_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6080 domain-containing protein"
                     /protein_id="HGZ2638852.1"
                     /translation="MSKILKYKNEIFLFILVVITYLIITKIFFSKTTIFYDLNNTYDV
                     LLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTDFNSAYG
                     FGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNVERFIYS
                     QFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKIGKMLKH
                     LLTFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLLYSVFYF
                     PGAGIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIIIFNLTLH
                     GIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNIYNIFLSLLLVTIIISNING
                     FIEILNIGIKSYPV"
     gene            complement(18142..19284)
                     /locus_tag="ACOIAP_001970"
     CDS             complement(18142..19284)
                     /locus_tag="ACOIAP_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGZ2638853.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLGGGTIPKYNKELSF
                     LSKDDESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHAIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANTVKV"
     gene            complement(19425..20291)
                     /locus_tag="ACOIAP_001971"
     CDS             complement(19425..20291)
                     /locus_tag="ACOIAP_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGZ2638854.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVSR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRVGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLFGVKLGFPVIIESIVPIIISVFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEKSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(20569..22116)
                     /locus_tag="ACOIAP_001972"
     CDS             complement(20569..22116)
                     /locus_tag="ACOIAP_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2638855.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKLVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVNKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMRHTPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVLNMLSGKINEETMRELNYQVDELGKSPEDVAHSF
                     LVKEGLV"
     gene            complement(22109..23245)
                     /locus_tag="ACOIAP_001973"
     CDS             complement(22109..23245)
                     /locus_tag="ACOIAP_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638856.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSGEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDVDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(23508..24605)
                     /gene="dinB"
                     /locus_tag="ACOIAP_001974"
     CDS             complement(23508..24605)
                     /gene="dinB"
                     /locus_tag="ACOIAP_001974"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGZ2638857.1"
                     /translation="MELHRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLKK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLNIDEEETRNILDELCEEVCH
                     RLKSSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRRGIDNLLRNVEMNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(25001..26506)
                     /locus_tag="ACOIAP_001975"
     CDS             complement(25001..26506)
                     /locus_tag="ACOIAP_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGZ2638858.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHEHKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAAV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(26767..27117)
                     /locus_tag="ACOIAP_001976"
     CDS             complement(26767..27117)
                     /locus_tag="ACOIAP_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6483 family protein"
                     /protein_id="HGZ2638859.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGKVNEAEEILFDKAKTVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(27339..27530)
                     /locus_tag="ACOIAP_001977"
     CDS             complement(27339..27530)
                     /locus_tag="ACOIAP_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638860.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(27648..28562)
                     /locus_tag="ACOIAP_001978"
     CDS             complement(27648..28562)
                     /locus_tag="ACOIAP_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2638861.1"
                     /translation="MKKIILKDILFLVTTLSLIVILLIVVNITANGKIKSTIKSYLKS
                     DKNSVSQNDIQSSTKNTEFKTTILNTGKSDCILVEIGDKVIMIDSGEDKNGKQIVDRL
                     KEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKA
                     DIEPVLLKENMNIVINSAEINIQSALKSKYESSNDYSIITSISYGAHKFLFAGDAEEK
                     RLSEFINGNTLKYDFVKIPHHGRYDKLTEAFLESISPKYAVITCSEKKEPDEEILKIL
                     EKLNIKTFLTSNGEVVINSDGKTLNVNQ"
     gene            complement(28696..30192)
                     /locus_tag="ACOIAP_001979"
     CDS             complement(28696..30192)
                     /locus_tag="ACOIAP_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2638862.1"
                     /translation="MFEFETQLKRLKHEVLTAVAKLSIEENLTKENIQKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVGLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFIDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKIFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKCLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSIQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEGVNLER"
     gene            complement(30472..31962)
                     /locus_tag="ACOIAP_001980"
     CDS             complement(30472..31962)
                     /locus_tag="ACOIAP_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2638863.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEENEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEEKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMENGEDFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            32429..32629
                     /locus_tag="ACOIAP_001981"
     CDS             32429..32629
                     /locus_tag="ACOIAP_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGZ2638864.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            complement(32809..33687)
                     /gene="speB"
                     /locus_tag="ACOIAP_001982"
     CDS             complement(32809..33687)
                     /gene="speB"
                     /locus_tag="ACOIAP_001982"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HGZ2638865.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVYEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFEKIVNMLNGKNIYITIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISEKIK"
     gene            complement(33677..34528)
                     /gene="speE"
                     /locus_tag="ACOIAP_001983"
     CDS             complement(33677..34528)
                     /gene="speE"
                     /locus_tag="ACOIAP_001983"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGZ2638866.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKKYMDICSCKLDDERVNLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(34558..34971)
                     /gene="speD"
                     /locus_tag="ACOIAP_001984"
     CDS             complement(34558..34971)
                     /gene="speD"
                     /locus_tag="ACOIAP_001984"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HGZ2638867.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(35058..36533)
                     /locus_tag="ACOIAP_001985"
     CDS             complement(35058..36533)
                     /locus_tag="ACOIAP_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HGZ2638868.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITFEKV
                     RKEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
BASE COUNT        11910 a         6649 c         3852 g        14563 t
ORIGIN      
        1 ccttccaaat atataaatac aattatataa attttcatcc tcaattataa catagaatat
       61 gactatctat atgctaaaat tatccatttt caaataaagg taactattat taaaaatatc
      121 aacttatagg atttatatcc catatacgat tttcaatcaa aaaaacaagg gctaaaaagt
      181 gaattgtaca ctttttagcc ctttattaat tattcattta tttcatgtaa gaatagccca
      241 catcttactt taggttcaaa ccatgttgat ttagctggca ttatcttatt tgcatctgct
      301 actcttatta aatcttcaat actagtagga tacattgcaa atgctacttt catatcttca
      361 ttaactcttt tttctaattc ttcaagacct ctaatcccac caatgaaatc aattctttta
      421 tctactctag gattgtcaat tcctaaaata gcatcaataa catagtcttg taatatagaa
      481 atatctaatg agtcaacagg gtcttctatt tctaataaat ttttatttgc tttcatttta
      541 taccacttat cacataggta cattccgaaa gttccttttt tgtcaggttt atatttttct
      601 tttccttcta tttcttctag ttcaaaattt tcttttattt tatttataaa ttcttcctcg
      661 cttaaaccat ttaagtcttt gataacccta ttataatcca aaaccattaa attttcatct
      721 ggagcaatca ttgctataaa gtaattaaat tcttcttttc cagtataatt tggattttta
      781 gctctcattt ctttggctac attttctgct gaagctgtcc tatgatgacc atctgcaatg
      841 tatagataat ctaattttct aaattcatct actaggttac atattatatc atcattatca
      901 atcttccata ctgtatgctc tatcttgtca tctgttataa aatcatataa aggttcatta
      961 ttattcataa aatcattgat tatatcatct atcacccttt gatgtttata agttacaagt
     1021 atagttcccg tattagcatc acagtatttt atgtgtttag ttctatcaat ttccttttct
     1081 ggtcgagtgt actcatgttt ttttattgtt ccattcaagc tttcatcaac tgatatacat
     1141 gctactatac caacttgagc tctaccatcc atgatttgtt tatatatata tatacactct
     1201 ttatcatctt ttactagaat ttcttgtttt cgaaactcat ctaaattttc tcgcgctttt
     1261 aaataaactt tttcatcata taaatctata ttttcatcta aatcaatctc tgatttatct
     1321 atatgcaaaa atgaatatgg attcccttct gcaattcttc tagcttcttt actattcata
     1381 acatcgtaag gaagtgctgc tactttatct actatatatt tatttggtct aatcgcctta
     1441 aatggtttaa tcgttgccat tactaatttc ctcctaatta tacaaaatat tttataatgc
     1501 tacccctatt agattgttga agtcaagaaa gaaatcttga atcacattta ctatttcgtc
     1561 tcctattctt tcttgagctt ctactgtaga tgccccaata tgaggtgtag gagaaactct
     1621 tggatgattt actaagtcta gatttaatgt aggttcttgt tcataaacat ctatagcagc
     1681 agctgataat ttaccttcat ctaatgcttt tagtaaatct ttttcatcaa ctaaaccacc
     1741 tcttgcacag tttattaaat aagccccttt cttcatctta tttatttctt tttcagttat
     1801 tactgccccc ttattcttat caaatggtat gtgtaaagat aagaaatctg ccttttctaa
     1861 aacttcttcc atatcacaga atttataatt gttaaagcct tgcgcttcac ccattatgtc
     1921 agtatatata acattcatac ctaataattc tgctctcttt gcaacttctt ttgcaatcct
     1981 tccaaaacct ataagtccaa gtgtctttcc attaatttct gtacctttat attttttctt
     2041 ctcccatttt ccatctctca tagttacatt tgcagtattt atgaatcttg caagaacaaa
     2101 taattgacct attgtaagct ctgcaacaga tatactgctt gcatttggag tattcataac
     2161 ttttatgcca ttagcttgag catatttaac gtctatatta tctagtccta ctcctcctct
     2221 tactatcaac ttcaactttt taccctctaa tgctttatct attacatctt tagtaacctt
     2281 agtagctgaa cgtactacaa gtacatcaac atctttaagt ttatctccta aaacatcttt
     2341 ttcataaaac tgctctatca cattaaaatt taactctctc aattttttcg ctgcttcttt
     2401 ctctattcca tcagtaacta atatattata cataacaaac tcctccaatt tttattcact
     2461 taatttttcc aatttttatt tttttaagta ttttcatcaa taaaacactt tacttaattt
     2521 aactttctgt ttatataatt ttcaaaatat ttttttatta aaatcatatc aaattttcct
     2581 attgtttgtt aaaaatttaa tacttaattt ttataaaata ttatttacta tatattctaa
     2641 atttatctta aaatatacat atttttacaa tattatttat taaaacctaa tatatcatca
     2701 atattatcta ataattcttg tacatcttcg acagtatagt cacccatgtg tgaaattcta
     2761 aaagtttttt cttttaaatc tccatagcca tttgctattt ggaatcctcg ttcttgtaat
     2821 tttgaattta aatttgatac actaatacct tgagtatttt ctataacagt aagtgtattg
     2881 gataagtgat tttcattggt aaaaatttgg aagtgttttt tagcccagtt tctaactaag
     2941 tttgccatgt cttcatgtct gttgaatctg ttatctaggc cttcatctaa tatattatct
     3001 aattggaaat ctaaagcgaa catgtgagaa agagatggtg ttgaagggta ttggtagttt
     3061 ttcttgatta agtattcata cattgctaac aaatcaagat atactcctct aaaaggtact
     3121 tgcttagctc tatcgattgc tttttgagaa aatgtgcaaa tagacattcc tggtggtaat
     3181 cccagtgctt tttgtactga tgttatacaa atatctattc caatcttatc aacctcgact
     3241 tttattccac cggctgaact tacagtatct acacagtaga ttacatcttt atacttttta
     3301 acaacttctc caatttcttc tattggattt cttattccag ttgaagtttc attgtgagtt
     3361 acagttatta aatcgtattc tccggtagaa agcaccttat caaccatttc tggcgttgtt
     3421 gcctctccta attcaacttt aaatatatcc gctgggacat tattagccac tgccattttg
     3481 taccatctat caccaaagga tccacaggaa aatactgctg cctttttgga tgtacaggaa
     3541 cgaatggagc cttccattaa accagttccg gatgacgtgg ataaaagtat cgtgttgttc
     3601 gtatagaata gtttttgcat tttttcactt atactctttt ggagtacaga tgcatctttt
     3661 cctctatgtc ctatcattgg tgtagccatc ttttgcaaga cttcttcttt aacatcaata
     3721 ggaccaggaa taaataattt cttactcatt ataattcccc cctttttagt ttgtaatatg
     3781 gatagcgttt ttactgtcct tatttttaat aactataata tcaagctgaa ttaactatgt
     3841 caacataaaa tttatttttt atatataatt tattttatat attttatgaa aacatatatt
     3901 tcgcaccttt tcataagtct gaatattctg aattaattcc tcaaaaaaaa tatacttttt
     3961 atctatataa attaattttt tcagtatata aatttaatgc tattacgata aatcttttta
     4021 gtataactaa tttattttta tcttgtattt ttattgtatt tttgaatttt attttttata
     4081 aatataaaat ttatgtttga aaatataaaa tttttatcta atcaaagttc aatatattcc
     4141 actttttctt tcgattcttc aaagaaccat tcttcattag aaaaatcacc ttctgcaatt
     4201 tgtccaatag gcattttcat atactttcca gttgctgtta ctgctacatc tccatttggt
     4261 agaattattt ctcctgtacc ttcaaataat tttctgtttt ctttagttat tcttccaaca
     4321 acttttatag tagcatctgt tggtactggt ttcttatatt tcaattccaa agacactgtt
     4381 actccccata tttggtcatc atttatactt acagctcttc caatagtctc gtctaatatt
     4441 gcagcagaca tacctccatg aactcttcca ggataacttt gatgccaatc ctttgtatta
     4501 caaattgata caagctcccc attttcaagt tcataaaaat ctgctttaag tcctaactca
     4561 ttttgtgttc cacaaactaa acaagatttg ctactatttt gcttctttaa aactttatac
     4621 tttgccaaaa aatccatctc ctaaccgaca ttagtagtcg cttaatatta aataattcta
     4681 aaatatatta tataatatta ataaaatccc tgcaaacttc taataataaa aataggctat
     4741 ttcaatatga taagtttaat ttaaagtatt attttctaaa aaataacttt atcaaaatag
     4801 aaactcaaaa tagatataag cctctttttc gttattaaaa tattaaaaat atatttgact
     4861 taatataaaa aagagtgcct cattaactaa taaagtttat tttgagacac ccctcataaa
     4921 acaaattata ctataataga tttgtagcaa tcttccaagt tatatattta aattatatta
     4981 tacaaattaa actataattc taaatttcat ttactattaa ctcgcccatt tcttttgttc
     5041 ctacaacagt tcccacacca ttatggatat caatagttct ataaccttta ttaagtatac
     5101 tttgtacagc atattcaata cacttagctt cttcttctag gttaaaacta tgtcttaaca
     5161 tcatgcttac agatagaata gttgcaattg gatttacaat atcttttccg gctatatcag
     5221 gtgcacttcc atgtattggt tcatacatac caaaactatc gtctctaagt gatgctgatg
     5281 gtaacatacc tatagaaccc gtaatcatag atgcttcatc agatattata tctccaaata
     5341 tattattagt tactattaca tcaaattggc taggttctct tacaacttgc atagcagcat
     5401 tatcaacata catatgtgat agctctacat cttcaaactc tttagctaaa tcttccatta
     5461 tacttctcca aagtcttgaa ctctcaagca catttgcctt gtctacactt ataagttttt
     5521 tacttctatt tctggctatt tcaaaagctc tcttaccaat tcttcttatt tcattttcgt
     5581 tatatgtttc tacatcataa gcattttcaa taccatcaat aatttttctt ccacgttctc
     5641 caaaataaat gccccctgtt aattctctta caacaacaaa atcaatgcct ttatcaacta
     5701 tatccgttct aagtggtgaa gcttctttta tactttcata cattgtggct ggtcttaagt
     5761 ttgcaaataa acccaatgac tctcttaatt ttaaaagacc agactctggt cttgtatctc
     5821 ccttacattt atcccacttt ggtcctccaa cagcaccaag taatacagcc tcgttttttc
     5881 gacaaacttc aacagtttta ttaggtagag gttctccagt ttcatcaatt gcacaccctc
     5941 ctgctaatac atattcacaa tcgaatctat gattaaattt acaacaaatt ttatttagaa
     6001 cctttatacc ttcatctata atttccggtc caacaccatc accttttatg actgctatat
     6061 tacaattcat actccactac cccctatttg cttttattga gttaattaag ccttcattta
     6121 atataatatt ttgcataaac tctggaaatg gttctgcttt atattctttt ccttttgtta
     6181 tattttttat cacacctgtg gaaaaatcta cttctatctt atccccttcc tctatgttat
     6241 ttgcagcttc ttcacattca agtataggaa gccctatatt tatagaattt ctaaaaaata
     6301 ttctagcaaa agtagaagca atcacacagg atactccact ttcttttatt acaattggag
     6361 catgttctct tgatgaacca caaccaaagt ttttagttgc aactataata tctccctttt
     6421 ttaccttaga gataaattta tcatcaatat cctccataca atgtgttgct agttctttat
     6481 aatcagctat atttaaatat ctagctggta ttattacatc cgtatctata ttatctccga
     6541 atttaaaaac acttccgtta gcaatcataa attttacctc cattaaatta tttctgatgg
     6601 ctttgatatt tttccagtta tagctgatgc tgctgctaca gctgggcttg caagatatac
     6661 ctctgaatca acatgcccca ttcttcctac gaaattccta tttgttgttg aaatagactt
     6721 ttcacctgat gcaagtattc ccatatgtcc ccctagacat ggtccacaag ttggtgtaga
     6781 aactgctgct cctgcttcta taaaagtagt aatatatcct ttttctatag cttcaagata
     6841 tactttttgt gttccaggaa atatcataac tctaactcca tctgctactt ttttgccttt
     6901 cattatctca gctactactt caaggtctga tattcttcca tttgtacagg aacctattac
     6961 aacttggtct atctttatat ccttatcaat ttcatctact gttctagtat tttcaggaag
     7021 atgaggaaag gctacggttt cttttagttc agctaaatct atttcgtata cttcatcata
     7081 gactgcatct tcatcagctt gatatacatt tacatctttt gttattgttg tacacttatg
     7141 tgaatttata tattctatag tcttatcatc tactggaaaa attccatttt tagctcctgc
     7201 ttctattgcc atgttacaaa tagtaaacct atcatccata gataagtatt ctactccttc
     7261 cccgcaaaat tccatagact tataaagcgc accatcaact cctatcttac ctattatatg
     7321 aagtattata tctttaccac ttatccattt atttggttta ttcttcaaaa caaattttat
     7381 tgctccagga accttaaacc aacatttccc tgtagccata cccgctccca tatcagttga
     7441 acctacacca gtagaaaatg ctcctaatgc tccatatgtg caagtatgag aatcagcacc
     7501 tataattaca tctccagcag ttactatacc tttttcagga agaagaacat gctctattcc
     7561 catatctcct acatcaaaaa aatttacaac tccttttgac tttgcaaaac ttcttgtaaa
     7621 tttacattgt tctgcactct ttatatcttt gttaggtgta aaatggtcta aaaccatcac
     7681 tactttagtc ttatcataaa catcttcaat tcctaatttt tcaaattctc taatagctac
     7741 tggtgatgtt atatcattac ctaaaactat gtctaaatct gcttcaatta actgaccttt
     7801 cttaacctca tttaacttag catgtttggc taagattttc tgcgtcatag tcatccccat
     7861 tttttacttc ctcctcaata taacttttat ttattgcatt cataagtgca ttaatagctg
     7921 ctgtatttat gttttctgat atacttacac caaaatatac ttcattattg tgctctattc
     7981 ctacataagc tacccctctt gaatgtgacc cttcctctaa tgcatgttcc caataatatc
     8041 taaatttata atctttcatt ccacattgct ttagtgcatt attaaatgaa tctacaggtc
     8101 catttcctac accaacaatc ctttgttcat ttcccatata acttactctt gcagtcatct
     8161 caatcatgtt agtatcatta gaatcatcat tttcatagtt taattcatcc attgatttta
     8221 ttttatattt cttaacctta tagggactct caacatcaat atattctttc ctaaataaat
     8281 taaatattgc ttcactacta agctcttccc cgattctatc agattctatt ttgactacat
     8341 ttccaaaatc agaatgcata ttcttaggta tcataaatcc ataatctgtt tccattatat
     8401 aaacagctcc tccttttcca gattggctat ttattctgat aatttctttg tactctcttc
     8461 caatatcatg agggtctatt ggtaaatacg gaacttccca gtaatcatta tctctgtttt
     8521 tcattgctat catgcctttt ctaatagcat cttggtgtga acctgaaaag gcacaatgta
     8581 caagattacc tacatatgga tgtctatcat gtactataag ttttgtacag tcctcatata
     8641 tctctcttat cttatctata ttactaaaat ctagttctgg gtctattcct tgtgtgtaaa
     8701 gattaagtcc aacatttact atatccatat tcccagttct ttcaccattt ccaaatagcg
     8761 ttccttcaag cctatctgca ccagctaata atccaagttc acttgcagct gtacaagttc
     8821 ctctatcatt gtgagtgtgc aaacttagta taatagaatc tctacaactt acattttcac
     8881 aaaaccattc tatttggtct gcatatatgt ttggtgttga catttcaact gttgatggaa
     8941 gatttattat tacttttttt tgtggagtcg gtttccaaac atctatcact gcctcacata
     9001 tttcaagtgc ataatccatc tctgttcctg taaaactctc tggtgaatat tcaaaagtaa
     9061 attctgtctc tggatatttt tttacttctt cattaaataa ttttgcccct tcaactgcta
     9121 tatctattat ttcttgttta ctcatattaa aaaccacatc tctttgaaga acagatgtag
     9181 agttatataa atgtataatt gctttcttac atccctttac tgattcaaat gtcttttcta
     9241 taagatgagc cctggattgt gtaaggactt gtatagttac atcatctgga atcatattct
     9301 catctattaa ttttcttaaa aatgtatact ctgtatttga tgctgatgga aatcctacct
     9361 ctatttcttt aaagcctgta tcaataagca ttttgaacat tctgactttt tcatttacac
     9421 tcataggtgt tggtagtgac tgatttccat ctcttaaatc aacactgcac caaattggag
     9481 ccttaaatat ttcattatct ggccatttac gatttactat ttgcatttta tcatattttt
     9541 tatactttcc acacttcata ttatttcccc cttttttgtt tttttgtatt cagtatacct
     9601 tatatcgacg caatactgca caattcataa gaataaatgt caattttatc attagaataa
     9661 aaataacctc atctctaata aaattagaga cgaggttttg ctcgcggtac cactctattt
     9721 agctttctaa aaagctccct tagtaatagc caatacaata attataatga ctatatttcc
     9781 tataacgtgg aattactccg attattctaa gatttaaatc ttagaaaaca gctcctagac
     9841 aagttcagaa ctatcaactg ctaaatcaca ccacccttta gctctctgaa agtttcatgg
     9901 ttcttactac ttctattcat cacttttttt atcatttaaa ttttctaaat attttgattt
     9961 aatagttatt atatacacat taaaatatat tgtcaacaca aaaaataatt atctcgattt
    10021 tttatttttg ataagcaatt ctataaaaca tgctaactat tgaaaacagt atgatattat
    10081 gccttaaact ttttcatctt ttcatctatg atattcaata attttttttc atcttccaaa
    10141 ctcaatgcac ttaatctaat tttataatta gattcatcag tgtatatatt taatatattt
    10201 tttaccactt ctattttttc tattatctta taattaaact tttggctttg tttagatttt
    10261 atactgaata tacattgatt atttattaat attgaatgat tatcgagagt aatatacact
    10321 tttccctcat atttatttga aaaatcacga ccttgcttaa atagaaaaac tgctgttatt
    10381 atacataaaa tatataatat tgtcgttgaa tatataaaaa ttgtggctaa aattataagt
    10441 gccaaaacca tatatatagc cattcctctt ttaaaataac cattgtcata ataattcata
    10501 tagataaact tatttttact caaatttttt cactcccaat attctaaaaa tttatatcaa
    10561 aaaatcctat aatttcatct tcatgataat ttatgactaa ttcatctgga aaatctactg
    10621 attttaaaac tttctctgca ttttcaaatt ttcctataga ataacatata tgagagtcag
    10681 taccaagaat tactcttaca ccatatgttt tacacaatgt caacatatga cttacatttt
    10741 cccaagtacc agttctatga gagtttgaac ttaatgatga attatttatt tctaaaagga
    10801 tatttttatc tttagctttc tttactatag gttcataatc taaaggatac ctactgtcat
    10861 ctggatgtcc aattattttt accttaggct tatccatgac ttttaaaata gcatttgtat
    10921 tttcttcttt tgtacctgaa gctatacaag gtctatgcaa acttgcgatt atataatcca
    10981 aatgttgcaa catatcttct tgaacatcta aattaccatg ataatccatt atatttcctt
    11041 ctatccctct aagaatcttt acaccttgca cttctcgtgg gagcaaatgc aaattataaa
    11101 aataaaatgg atgtggccct cctggcatat taggtccgtg gtctgatatt cctaagtatt
    11161 ttatattttt attactcgcc tcttcgacat tttccttgaa agtactatgt gcatgtccac
    11221 ttattagagt gtgacaatgt acatccataa tagacttttt cattaaattt cctcctaatg
    11281 ttttacataa attcgtgaaa atagctaaag ggctatttca aaactaaagc tgtcataaca
    11341 gacagtgtaa cgttttaaaa cagccccatt ttcaattatt ttacacttct aaatctttaa
    11401 atttatcttt aaataattct ccaatacttc ctaaagattc ctctacttct aagtattctg
    11461 ttatatcctc ttctggctct ctagttgctt cttttattga aaccaacatt cttttagtct
    11521 ttggtttaaa atcaagaatc ttaactttaa cctcatctcc aatattaaca acattagtaa
    11581 ctttagccac tctagtatca cttaattcag atattggtaa atacgcatct acaccttctt
    11641 taatttgaac aaaagcccct ttttctatta ttctaagaac tttagcattg acaacatcat
    11701 caatctgtac ttcttttgct attaaatccc aagggtcatt atttatgtct tttaatgcca
    11761 aggcaatttt tttagtttct ttatttacat ccaacacata aacttctact tcttgtccct
    11821 ctgaaacaac atcttcaaca ctttcaactc ttgtccaagc taaattgttt atatgtgcta
    11881 atccttcaat cccaccaata tccacaaatg caccataagg cattatcttt gttaccttac
    11941 catctctttt ctgtccaact tcaagagagt taaataattc ttctttagct gcttttacac
    12001 gagctttttc ttcttctctt tcttgcttaa ttcttgctct ttcagcttct ttttccgcct
    12061 taatttgagc tcttctttct tctctctctt tatttatacg ctcttgtaat acatctctat
    12121 gagatgctac aagtctattt tttctaatat ccaattcttt tatataaact tctaagttaa
    12181 gaccaacaaa tttagatgtg tctgtaataa attttgtatc aagttgagaa attggtataa
    12241 aaaatgtata tgtattgtaa ttagcaaata cacctttatc tatattcttt tcaacattta
    12301 cagttattat tctatgttca tcataagctt tttgtaactc agcaaaatca tttcttttgt
    12361 caagttgtaa tttagataaa gttattgtcc catctttttg agatactttt gttattacag
    12421 cagttatttc atcacctata tggtatatat cttctatata ttgatttttt tctatgttca
    12481 attcacttat aggtattatt ccatcaaacc catagtctaa tcctaattgt acttcatcat
    12541 ttctcactgc agttattttt ccagttgtca attctccaac tttcactttg ctgaatactt
    12601 gctcttgctg gtcaagtaat tcttgcattg ttaaatcatt ttccattata aacatccttt
    12661 cctcttattg attatcatat ctgtaaatat tataccatta atattgcaaa tacttacatt
    12721 tttcttacta taatttttaa aataaattca gcttcatata tttatacatt atagaaaata
    12781 tcttattaaa ttaaaataca aattctaatt tttatctaat aaaatatttt cataaaaaat
    12841 ttatattgta tatcttattc ttctattgct ttaggttttg atagaaaaca tttataaaat
    12901 ataaagaaag aaattgctgt tatagtagct gctgttatat ccgcaactgg ctctgctaaa
    12961 attactgcaa aaagtttttc attaaagaat gttggaagta taaatattaa aggtattaaa
    13021 agtacaatct ttctaagtag agctaaaact aaagatattg ttgcttttcc aagtgctaaa
    13081 aatgtctgtt gacaagctat ttgaatccca aacataaaag caccagcaaa atatattttt
    13141 atactccaac tagtcatact aagtaactgc ggattcttat taaatatact aacaaaaaat
    13201 gtaggaaata tcattaataa aagccacaaa atagtagagt atgtaagaca tgataataga
    13261 cataacttaa atgtcttttt tactctatca agttgacctg aaccataatt gtaacttatt
    13321 attggttgtg ctccttgtgt aacccccata ttaggaagca taagaatttg cattatactg
    13381 ctcattatgg ccattgagcc tactgctaaa tctcctccat acatttgtaa tttactattt
    13441 aaggatataa gtactaaact ttctgtagat tgcattataa atggagagat tcccaagcct
    13501 aacactggta agacgatact tgcttttggt atcatatact tcttttttat tttaagtatg
    13561 cttttctttc caaaaagaaa cataagcacc caaatagcag aaactccttg tgcaattata
    13621 gtagctaatg cagcgccttt tacgcccata ttaaaaccaa atataaaaat cgggtcgagt
    13681 attatgttta tcaaagcgcc tatagcaact gtcatcattc cagttgtagc aaacccttgg
    13741 gtatttataa aagtattcat acccattgaa atctgaacaa atactgttcc cattaaataa
    13801 atgtttaaat aatccattga atatccaatt gtagattcac ttgctccaaa tatccaaagt
    13861 aaaggctctt ttccaatctt aaaacctata gtcaaaagta ttgctaaaat taccagtaca
    13921 gaaaaactgt tactcattat tttctctgcc tcatcattgt tttgctcccc catttttata
    13981 gcagctaatg gacctcctcc cataccaatt aaataactac aggccattat tataattatt
    14041 attggaaatg ccactccaac accagccata gcaacttctc cattttccat tctaccaata
    14101 aaaatcctat cgactatgtt gtataaaaca tttacaattt gtgcgataat agcaggtgtg
    14161 gcaagtttaa ataataattt acccacactc tcattcccta ggttagtgct tgaattttcc
    14221 attttaaaac ctcctcaatc caataattaa aatatatcac taaaatttta ttctctataa
    14281 aactttcact ttatcagcag acaaatttag agtgctttcc ctacaagtaa tactatacta
    14341 tatttctttt gccatagtaa acattttaga actaactgaa tttaaatact ttatctcact
    14401 ttttatttgt tcttaaaaat ttttcacatg tactcataaa aaaactatcc aagtatatta
    14461 cttagatagt tttatattat atgtaaagaa agagctgaaa ctataactcc tgatagcaaa
    14521 ttgccaagaa atactcccat aaaagcatct tttattctca tttttaatat ggaagctata
    14581 gcagatgcag tccatgttcc tgtagttggc agtggtatac ccacaaatag tattatacca
    14641 attatcgaaa cactttttaa tttcttcatt cttgagttta ttttcctatc aattacatca
    14701 gcaatccctt taaatagttt cttccctctt aaaaattgta atatatgtct aaatgtcaat
    14761 atcaagggaa tcgataccaa tgtagaacct attacactaa atacataaac ccatatagga
    14821 tttaatccca ttgcaatccc tataggaatg gctcccctta attctgttac aggaaccata
    14881 gataaaatta atatgtgtaa atatcccaaa ctattccctc ctattctaag tgacattaag
    14941 ttatgaattt atttgctcta taacctcacc attcttttta ctaactaaaa acgcattttt
    15001 agttaatgaa agcattggta aatcactctt agagtctgaa tatgcatatg aattttcata
    15061 atcaatctct ataccaagct tacctaatac agcctttatt ctttttactt tttcaattcc
    15121 cttacagttt tctccaatga attgattttt atatcttgaa ttttcataaa aaaactcagt
    15181 gcctataacc tcatctgcaa gaccataata cttaaaatat ttcatatatg catatggaga
    15241 tgcagttatc ataattataa cattataacc ttctttattt ttgtaaataa ccttttttat
    15301 agattcatta atttttttca ttatgcaatc atcaaaaaaa ctttttaaat cttcttcact
    15361 aaaatctact attggataaa agattgcctc ttttgctttc ttcaacggta ccattctaat
    15421 caaatacata aatagaataa aaataatata gggcaacttt ataatagttt taaaagtttt
    15481 attttttaaa gagtaaataa aaaaatctat catgctatca gtatttataa cagtataatc
    15541 tacatcaagt aataatacac tttttttcat aagtatatcc ccatcctatc actaaaaata
    15601 tcactaaaaa atcaatatta ttaaacatgt aattatccac aagattacgt ttatttttaa
    15661 agcattatct gttaggataa tatcagtagg attactttca tttgtagtgt taattatata
    15721 attatatcta agtacaccat aaactacaaa tatggttgta aatatcatat gaggcttttc
    15781 tggattgctt gtagaatata gtgcataaca tacaattgta gaacttaata taactatcat
    15841 catttgattt agattttcta cgtcgtaatc ttctagtatt tttctatgtt caactgcatc
    15901 acctcttaaa gtttctattt cttttttacg ttttccaaga gctaagtaca gagataagaa
    15961 aaatgtacat agaattatcc aatttgacaa actaacactt atggccacac atcctgcata
    16021 aaccctaagt ataaaaccaa gagatatgga aaacacatct aatagtatta tattctttag
    16081 tttaagagaa tataatatat tgtttatcaa ataaagactg agaattatag aaagattaaa
    16141 actaacaact gttgataaac agactgaaat taaagataat actacaaata gtatataagc
    16201 actttttttg cttattcttc cacttgccac tggtctatta cattttttag gatgtttttt
    16261 atccttatcc atgtctatag catcattcaa cgcatatact gatgatgaca ttaggcaaaa
    16321 acacacaaat gcaataaacg tatttaataa taaatttata tttagtatgt tgtttgaaaa
    16381 aattatagct gaaaatacaa agaaattctt tatatattgc tttattctca ttaactttat
    16441 ataatctgaa attttagtaa gaagccttat atttgtattg gtctgtttca taaacttact
    16501 accctttcaa tattattttt taaacaggat atgattttat ccctatgttt aaaatttcta
    16561 taaatccatt tatattactg attattatag taaccaataa caatgataga aatatattat
    16621 aaatattttt ttcatttttt ctaagagctt ttgtaaagta agccaataag attataactg
    16681 caaaactaaa atttatagcc ataatacttg aattgactag attatatcct actataccat
    16741 gtaaagttag attgaatata attattccca tacatagctt aggaactctt ttttctgaat
    16801 tttcaataac tgataaaaca caaaaacata aagccaataa tgtaagaatt actggtattg
    16861 tagcaacttc tccattttgc aaaaataacc cttttttaat acctgctcca ggaaaataaa
    16921 aaaccgaata caacagtctc tctataatca ttgcaatctt ttctaaaatt ggttctccac
    16981 ttataaattt cgtatcatac tgtattacat ttccaaggtt cataaaactc tcataagact
    17041 tcgttgaaac cacacaaata tatgccatta agataaatgt aagtaaatgt tttaacattt
    17101 ttcctatttt caatttaaac tcaaatatca tattaaaaaa atacaaatat atattactaa
    17161 tagttattcc aaatagagga atagctgcta attctactaa ataagaattt ttccctttca
    17221 tcttgtttgc aataactatg aaaaatatta atgaaaattg actatatatg aatctctcta
    17281 catttaaagt cataaatagt tgtggaaaag aaaatatcat tatcatagta agcaaaatta
    17341 aagttagtct ctgcattttt atttttttaa tatgattaaa aactaaagtt attgacatag
    17401 cactagttat tatttgtaga caaattagtc caaacccata agcactatta aaatctgttg
    17461 tcccaggatt tgctattgaa gtacaaaata ggtatattgg atatgcaaaa attgatataa
    17521 ttgctgaaaa taatatgtgc ttactattat cttgacttat agcaaataca tttaaattga
    17581 ataaaacccc tgtatctgta tctaacaata catcataggt attgtttaaa tcataaaata
    17641 tagtagtctt agaaaaaaat atcttagtta ttattaagta agttattaca actaatataa
    17701 ataaaaatat ctcgttttta tattttaata ttttactcat caatatatca ccatccattc
    17761 attatatagg atttgctgac acctacaatt tattccttat atttaatagc cctcttcata
    17821 atgttcttac ttgttttatt gtaattgaat agctctttat ttacaaccac aatatttgct
    17881 ttattgatgt tataatcagt caaacgttgt ttatataaca tagattagcg ttgtataaag
    17941 tgagaatttg taagcaatat taatgtaaaa tatttgaaaa attttatata aaaatataaa
    18001 attttgctta tgtaattaaa ctataacaaa ttaaagcata atttaaggag acaaaattat
    18061 aatctgtctc cttaaacact aaaactatgt tttaaagaat tactaaatac tatacaaatt
    18121 tcaaatataa tataaaatta attacacttt aacagtatta gctccatctt cttcccattt
    18181 tttaatctct tttagtctat ctattatagg taaatgctga gtacattcaa cctcacattt
    18241 tccacaagat atacattctt tagcttttgc cttactattc attgtataat tccaatgtcc
    18301 taagccataa actaactttg tcatttcttc atcgctcttt ttaaacatct gtttttcatt
    18361 gtaaaaaagc atataagctg gggtattaat accttttgga catactttac aatacccaca
    18421 gcctgtacat atttcgttca tattcttatt tagtctagtc tcaatagcat gtatatcctc
    18481 atctgaataa attctatttt cgtctgcaat tttacatgca tcatctatat cttgtttttt
    18541 attaaaccct atcaaagata tacttatttg tgaaattcct atgttgaatc ttaaagctga
    18601 ttctatagta ctttcatcat cttttgatag aaaagaaagc tctttattat actttggaat
    18661 agttccacca cctaatggat tcattgccac aacaccatat ccattatcaa cagcatactt
    18721 tgcacctttt aatctatatg gaaagttcaa tatattaatt cccatagtta caccttcaaa
    18781 cttattttca cttagaatat ctataacctc atctcctggt tgatgagatg aaaatactat
    18841 atggtctatc aatccttctt ctttacactt caataatcct tcatattgac ctccaggtct
    18901 cattgctagt tcataatgtt ccatcttcct aatattccaa acatgataaa aatttatttt
    18961 agatacgcct aatcgttcta ttgatttttt tacagcttct atagcttttt ctgatgtatc
    19021 acatgctttt ggtttttctt tagttgatac ataaaaatcg gtcttacctt cctttatcat
    19081 ttgtctaaag gctagtccaa atatatcttc acttctgtca tcacaatacc ctggtgctgt
    19141 atcaaagtaa ttaatacctt tttcatacgc atatttgact aaatcagcat tttcttgatt
    19201 acttttttct aaatcaaacc ttaatcctcc ataaccaact actgaaacca ttttccccgt
    19261 ctttccatat tcaacgtatc tcattgtaaa ttcctcctta gatatattaa gacttaattt
    19321 ctttatagaa aatattatac cataaataat ttttataaat tatttatggt ataatatttt
    19381 ttttataaat tatatttttt tataacttgc attttatagc taaattaaaa actataaaaa
    19441 ggttcaatat ggactattac ttgagcattc tcattaattt cttcctgtat ttgtttctca
    19501 attttatgtg ttaaatcatg agatttctct acacttataa atgggtctac cattacatgc
    19561 atgtcaatat aaatggaact tttgctacct ctacttctga tattgtgaac atcccttacc
    19621 tcattaaatt caaatacaat ttcttttata taatcctcat ctacagccac tctatctacc
    19681 aaaattccaa tagatggcct aaatattcca taagctgaat aaattatgaa tacagaaata
    19741 ataataggaa ctatagattc tattattact ggaaatccta acttgacacc aaataaagta
    19801 accaatacgc ctagagatac aaatatatca cttcttgtat gcaatgaatc cgaaatcaaa
    19861 acataactat ttagtttagt cccaactcta tattcataca tacatacaaa aatatttata
    19921 aaaagtgtaa taattaaagc aattaaactt tctatagtta tagcaggtac aactggatta
    19981 gctattcttg acactgcact aagaattatc ttaattgcta taacaaacaa cataccactt
    20041 ataaataaac tggttataat ttcaaatttt ttgtgtccat aaggatgatt tttatctttt
    20101 ggtttggatg caaagaaaat acctataagc cctactatat tagatgctcc atccgacaaa
    20161 gaatgaaatc cgtctgctgt catactgtaa cttttaattt gattaccaat aatgattttt
    20221 aataatgcta ctgcaaaatt agcaaataaa attatccata atacttgctt cactttctta
    20281 tagttatcca taacaaattc cccctccctt cgattcaata aaaaagctat ctatcaatat
    20341 caatcaacca gataataaaa tcgtatataa gcacatttac tatatttata ttcaaaattg
    20401 gttgtacttg ttcattcaat ttgaaactta attataaata aaaataaact tcttttttat
    20461 tattaaaata ataaaatata ttttatttca tacaaaaaaa gagtgcctca tgaactaaaa
    20521 agttcatttt gagacactcc attagagttt tgataaacaa ttaatttttt atactaaacc
    20581 ttctttaact aagaatgaat gagcaacatc ttctggtgat ttaccaagtt catccacttg
    20641 atagttaagt tctctcatag tttcttcatt tatttttcct gaaagcatat ttaaaacttt
    20701 ttctaattca ggatatttct tcaaagtatc ttctctcact aatggagctg cataatatgg
    20761 tacaaagaag tttttatcgt cctctaatat cttaagatta aactttttaa taagaccatc
    20821 agttaaaaat gcatctataa cctgagattc attattatct aaagctgtat atcttaaact
    20881 tccattcatt gcttttacat ctttgaattt taaaccataa tctctagaaa gtcctacaag
    20941 accatcctct ctattttcaa actccaaagt tggtgagaat gtaaattctt taccatattt
    21001 agtcaaatct gaaatagtat ttattccata cttttcagca gtttcaggca tcatggctaa
    21061 tgtgtaagta ttattaaatc caagagggtc aagtaaagtt aactgatttt ctttttccat
    21121 agtatctttt acaacattat atgcttcatc agcatcttta attggagtat gtctcattac
    21181 atttaccaaa agtgtacctg tataatcaac atacatgtct aactcaccag atttaattgc
    21241 attaaatgca acagatgaac cacctagatt taaattctta ttaactttaa gattcgtatt
    21301 tttttctact aattcagcat aaacattacc aagtataagt tgttctgtat aatctttaga
    21361 accaatagtt attgtatctt ttttacttga aaaactagaa ctaaaaacaa cgaacaacat
    21421 tgaaacaaca actactacag atattacttt aagtgctata taatttttct taggtgcttt
    21481 tggatttaat ccttttggag taactgcaac ctcaattttg ctaaataaat aatcaactaa
    21541 cagtgcaatt atacatgatg gaattgcccc tgctaaaatc atattattat ttacagtttg
    21601 aactcctgaa aatactaaat atcctaaacc accagcacct ataaatgctg caagagtcat
    21661 caaaccaaca gctgtaactg cagatattct aactccaccc attattatag gaagtgctaa
    21721 agggaattgt attttaaata atgtctgatt tcttgtaaga ccaataccct tagctgattc
    21781 caatactact gggtcaatac ttgttatacc tatatacgta ttttttacaa ttggaagtaa
    21841 tgaataaact actaccataa atatagctgg tttacttcct ataccaagta taggtacaag
    21901 aagacccaaa agtgccatag atggaactgc ttggactaag tttacaaatc caagtacaag
    21961 ttttctaaga gatgagattc ttgaaataat tattccaaga ggaacaccaa ctattatagc
    22021 tattaaaata gatgtaacag ttagactcat gtgttgtatt aaaagctcta taatcttatc
    22081 tttttgtaat agtataaagt taaaaaaatt agccaagtac actcacctcc atttctagga
    22141 attgttcact taaaacagaa agtaaactac ttctagtaat aagccctacc agcttatttt
    22201 catcagaaat aactggaata tatccaaccg aattacgatt cattacattt agtatttcta
    22261 ctaaattatc accttcattt acatgcaaag gctcacttga cataatatca gcaagtaata
    22321 ttgacttatc atcaacatct ttcatatctt ttacagtaac aatacctttt aatgtttttg
    22381 ctctatctat aattagtaag ctgtcaacct tactcgttct cataatttct atcccttgag
    22441 ttacagttct agtggaatta acagcaatag gattttttat cataatatct cttgctttta
    22501 tatattctgg attatcccaa actctatctt ctccgataaa atcttttaca aagtcgtttg
    22561 caggttttct aagtatattt tcgggagtat catattgtgc tattcttcca tccttcataa
    22621 tacaaatttt atcagctatc tttaaagcct catccatatc atgagttaca aatattatag
    22681 tttttttcaa ttcatcttga agagaaaata attgttcttg taaagatgtt ctcgttattg
    22741 ggtctaaagc actaaaaggc tcatccatca atattatttc agcatcagtg gcaatagctc
    22801 ttgcaacacc gattctttgt tgctgtccac cactaagctc tgaaggatac ttatttaaaa
    22861 attcaccact atcaagtcct accatctcaa gtagttgcaa tgttcttttt tcaatttctt
    22921 caacggattt ttcctttttt aggcgtggaa ttagctctat attttctttt attgtaagat
    22981 gagggaatag gcctgtgttc tgtataacat atcctatttt tcttctaagt tctatttcat
    23041 tttcctgaga aattggtttg ccattaatat atatctcacc agatgtaggt tttattaatt
    23101 tgtttataag cttcaaggta gtagtcttcc cacaaccact tgaaccaatc aaaactacca
    23161 atgtacctgt ttctacaact agagagatat catctaatat aacattattt cctatttttt
    23221 ttgttacatt tcttatctct atcataattt atcatcccct ttttcgaaca agcaaccttc
    23281 ttcaatatta taagttgttt ttataattat atcatactat tttatttatg taaacaaagt
    23341 acgactttta gagcaatatt tgtctgaata ttgacacaaa tataaagtat ttatatatag
    23401 tgtgtaatat ataatatcga aaagcaaaaa atataaaaat attcataaaa taatactagc
    23461 ttcaattata taatattaaa actagtatta ttttatttaa acaaaactca catttggata
    23521 ctatccatgt attcaaataa ggtaatatct ttataagttt cttttttatc acttaaattt
    23581 gatattgtca ctcccaatag cctaatttgt tttccattca tctcaacatt tctcaataaa
    23641 ttatctatac ctcttcttat atcattgtat tcgtcaatat aatgttctaa actaaggctt
    23701 ctagttatct ttgtaaagtc ctcatattta atttttaatg ttaatgtttt tccaaacttc
    23761 tcagaacttt ttaatctatg gcacacctct tcacaaagtt catcaagaat gttgcgtgtt
    23821 tcttcttcat caatattcaa attatgactt aatgtagtct ctgccccaac agattttcta
    23881 accctatttg gttctactgg tctatcgtct attcctctag caaatttata taattcataa
    23941 cctctttttt taaatatatt ttcaagctca aataaattta aacaccttaa atcatagcca
    24001 gtttttatac ctaaattttt aagagtattt gaagtaactt ttccaacacc aaaaaattta
    24061 ttcacaggta atttgtctaa aaagtcctgg gcattttctt cggttattac agttaatcca
    24121 tttggctttt ttaagtctga tgcaatctta gcaagaaact tattgtatga tacaccagct
    24181 gaagaagtga gaccaacttc tctaaatata tcttttttta tttgctttgc tatctcaatt
    24241 gatgaatcaa tatttttttt attttttgtt acatctaagt aagcttcatc taaagataat
    24301 ggttcaacta aatctgtgta tctataaaat atatctctta tttgctctga cacactctta
    24361 taaacatcaa atctaggtct tacaaaaact gcatatggac acctattgta agctacagct
    24421 gatggcatag ctgaatggat accaaacttt ctagcttcat aagaacatgt tgcaaccaca
    24481 cctctgcttt gtggatttcc accgacaata acaggtcttc cttttaattt tttattatct
    24541 ctttgttcta tagatgcata aaaagcatcc atatctatat gaattatttt tctatgaagt
    24601 tccatcatat cacctttaaa gtataaatag attaatttta tttatattac tttttaatta
    24661 taccaaactt atgtttcttt ttggtatttt ttcattattt tatttatata ttcatatttt
    24721 caataaataa aaccacctat aatccattaa cttcaatata atttataaaa aatccttaaa
    24781 aacacttgca aaaactatat aaaagcttta caataggtat tccaaggaac taaatttaaa
    24841 attccttatg gataacagta tatatattta atttaaatgg gatgttttaa aaacaaaaga
    24901 ctgtcttata caagacagcc tactgatttt attataattg taatggactg ctcaaactat
    24961 tactttaaaa cagcccatat ttttttatat aattttaact ttaactatag taaagatttt
    25021 gtgaaggata ctctgggtca caagttacat ctataccaag ctttctaaat gtttgttcat
    25081 catccctatt taatatagta gtagaatgag cttgacaccc ttttaataag gctaactttt
    25141 ccatagcaaa ttgtgcagtt ggattagtta cagcacaaat actaagtgca gttaacacct
    25201 cttgacaact aagtgaaaca tttctactag ctaaagtttt tgtttttaag tttatgatag
    25261 gctctaatat tacaggtgat attaagtgca tatcatcaga tatattagct aaatgtttta
    25321 ttgcatttaa tactgctgct gctgttccat tcattaaatc agaaccctta ccagttaata
    25381 ttgtaccatc ttctaattct aatgcaacta caggacaagt gtcattcttg tcagcacttt
    25441 ctttcaattt attactgtaa tttctagcag gtaatacaac atttctatct tctggcttta
    25501 agttaagttc ttccataatc attttcattc tgtcataagc acctttatca acttgtcctt
    25561 ttttatactc acaagcagtt ttaaagtatc ttcttattat ttcttctata gaagcttttc
    25621 ttattacttc atcatctatt attccaaagc caactctatt aacacccata tcagttggag
    25681 attggaaaat tgattctttt ccagttatct tttctattat ttttttaagt actggaaata
    25741 attctaaatc tctattgtag tttactgaca tttcaccata cgtttcaaga tggaatgaat
    25801 ctatcatatt cacatctttt aaatcaactg tagctgcttc ataagctata ttcaaaggat
    25861 gttttacagg cacattccaa actgggaatg tctcaaactt agaatatcca actacattac
    25921 ctcttttatg ttcatgatac aactgactta gacaagtacc aagttttcca ctattaggtc
    25981 ctggtgctgt aactactact attggttttg tagtttctat atattcattt gctccatatc
    26041 cctcatcact aactatagtc tcaacatctg acggatatcc ctttgttgga tagtgcttat
    26101 aaactttaat tcctctacgt tctaatttat ttataaatac agttgtagct ggttgtcctt
    26161 caaatctagt aattactaca ctatttacat ctagttcata acctcttaaa tcatctatta
    26221 atcttaaaac ttccatatca taagtgatac caaagtctcc tcttattttg tttctttcta
    26281 tatctcctgc atagacacaa attacaactt caactttttc tttcatatgt tgtaatactt
    26341 ttatctttgc attttcatca aatcctggaa gcactctttt tgcatgaagg tctcccatca
    26401 attttcctcc aaactctaaa taaagcttgt caaaattatt tactctttct aagatatatt
    26461 tagactgctc ttctaaatat tttttgtggt caaatcctac tttcatctta acacctcact
    26521 aaattaaatt tcttgttgat aacagtatat ttatatatat ttttttagta aaacatctta
    26581 taaaaaaatg ttaatacttt ttcactcaaa gtaatattat acaattaaga ttaatttttt
    26641 tcaagatagt tttatggtaa ataagatata cttatataac taataaaata agaatattat
    26701 atttttatat ataagtataa tattctcacc ttagtattaa tttatttcaa tattttcata
    26761 tatcttttac tctaaattca acactttcct aatatcttct atcccttgat aaacttcttg
    26821 tttagaaaaa ttcatagctt ctaattcttc atcagttttc tccataagca tagtataaaa
    26881 ttctattgct atatattgca tattttcact atttaccgtc ttagctttat caaataaaat
    26941 ttcttctgct tcgtttactt ttccctgaaa aactaatctt tttaaagtta taagtataac
    27001 ttcttcttct gtattataca ctaaatcttt ttcttcatat tcactgtatt ttttccccaa
    27061 taaaagtctt gcaaccataa gttttatctc attgaaaatc ttatccacta tagccatgtt
    27121 tacatctcct ataaataaaa tttattttct ttttaattat atcagacttt atagtaaaaa
    27181 ttattatatg taaatgaaat aatacaaaaa taaattttaa caataaaaaa agaaggtagc
    27241 gggggatttc cgactacctt caaacactag attgtgattg gtttggtatt ttgtttatac
    27301 ccaccaaaag ctttgttaaa tcatctaaat tgattttttt agcatccaca tcctccatca
    27361 aaaacgtcac cacattcaca aagtattaac aataatatta agaaaggtat ccatgcacat
    27421 aagtccattt cagcccaaca atcttggaat gctaagaata agaagaataa tattattatc
    27481 caccaagcac atccaccaaa tccgccttca ccaaaaaatc tatccaacat aatatgttac
    27541 ctcctagcca ttttgtatgt ggagtttcag ctcctaaaat atactatgtt taaggggtaa
    27601 tatttgctaa tgatttttta aaattttttt agatatttta aaaaaaatta ttgattcaca
    27661 ttcaacgtct taccatcact gttgataact acctctccat tagaagtcaa aaatgttttt
    27721 atattcaatt tttccagtat ttttaaaatc tcttcatctg gttctttttt ctccgaacag
    27781 gtaataacag catatttagg tgaaatagat tctaaaaatg cttcagttaa tttgtcatat
    27841 cttccatggt ggggtatttt aacaaaatca tattttaaag tatttccatt tataaactct
    27901 gacaaccttt tttcctctgc atctcctgca aataaaaact tatgtgctcc atagcttata
    27961 ctagtaatta ttgaataatc atttgaactt tcgtacttgc tttttaaagc tgattgtatg
    28021 tttatttctg cactattaat tacaatattc atattctctt ttagtagtac tggttctata
    28081 tcagcctttt taagcgagtc aatatattca tcatattgct tactatcttt cttataattt
    28141 gcctgtataa tattctttac tttaacacta gataacacac tatctactcc acctatatgg
    28201 tctttatcta aatgagttaa aatcaaatag tcaagtgtat ttattccttt ttcttttaat
    28261 ctatcaacta tttgttttcc atttttatct tctccactat caatcattat gactttgtca
    28321 cctatctcaa ctaatataca atcagacttt ccagtgttca gtatagtagt cttaaattca
    28381 gtattttttg tgctactctg aatatcattt tgactcacac tatttttgtc actttttaaa
    28441 taagatttta ttgttgattt tatcttacca ttagcagtta tatttactac aatcaataat
    28501 attactatta gagataatgt agtaactaaa aacaggatgt cttttaatat tatttttttc
    28561 atccaaaagc tcctataaat tttatttatt acatatttat agtatagcaa tcttaatgtt
    28621 ttaaaataca catataaaag gggcaaattt taggcatatt tgtggcatga taaaaaaatg
    28681 actgtatcaa aatgattatc tttctaaatt tacaccttca aattctttaa tcttatcatt
    28741 agataaaaca ctctttttag tagattgtcc attttttcta tcaaaagtat ttttagcttt
    28801 tacacctgat aaaaacttac ctgctccatt aatacaacct tcttcacaca tcattccttc
    28861 tataaaatta ccttctaatc ttcccaattt agccattgtc attgtctttt taatttgtct
    28921 tggaccagat acttttatag gttcaaaatc aaaactaagc cccttttcag caatatagtt
    28981 ctgtattgat ttagcaagtc caccagatgc tccaaatccc cttccaaaaa tcgaaccatc
    29041 atttatatct tcatttgaac attttgataa atctatatta aatgcttcaa ataatgccat
    29101 tagttcttca aaagtaagta cataatctac tgaatctttt aaacatttct ctgttgcctc
    29161 actcttttta gctgtacatg gtcctataaa tacaaccttg gcatcagaat ctattttttt
    29221 tactaatctt cctgttgcta ccataggaga cactgtagat gatattctat ctttttcatc
    29281 tgggaatatc ttctctatat acttaaaaaa tcctggacaa catgaatttg tcatgtaatt
    29341 atctcctgat tttattcttt caataagctc attactttca tgaactgtaa ctgcatctgc
    29401 tccacaagaa gcttctatca tatctataaa tcccaatgat tttatagcat tttttaactg
    29461 accatatgta atattactat ctatttgacc tgttatagct ggagctacta ttgcatacat
    29521 attttccttt tttgcaagtt tttttgcaac aggtgctatt aaactcttat cagatattgc
    29581 tccaaatgga catgctgaca tacatgctcc acaatttata caattatctt catgtatcat
    29641 ggctttcata gtgtttctat taaaatccaa agctcctgtt gggcaaacac tcttacaagg
    29701 tcttacaact tctgatatag catcatattg gcatgaactt ttgcacattc cacaagcctt
    29761 acataaatca tgatttatat atgctctccc atttatatag gaaattgccc caaatttaca
    29821 tgcctcctta catctatgag ccaaacatcc tctacaaagt tctgtaactg taaattcatt
    29881 tattggacat ctatcacatg ctgcttctac tatatatata atttgctcgt ctgtgtccaa
    29941 accaactgaa tctggattta tatctccata tttactattt ggagttaagc ttaatgcaag
    30001 ttgcgccctt tcaagaacta cctctctctc tttataaaca cagcatctat atctcgcctt
    30061 ttctccttta attatctcat atggaatttt ttgtatattt tcttttgtta aattttcttc
    30121 aatagatagt tttgctactg ctgtcaaaac ttcatgtttc aatcttttta gttgcgtttc
    30181 aaactcaaac ataagtaatc ctccctataa atcacatctt tttgctatat ttctactgtt
    30241 atgtatattg tatattttat ttatttccat aaattattat aacataggca tatactttgt
    30301 taagttatat acaaaatatt atatatgtaa tttttatttt aagcgtatat aatttttatt
    30361 ttagttgttc aataattaaa tatataaata aaaatagagt tgtcctaaag ttaaacttca
    30421 acttagaaca actctattaa caatatgtat ttttgttgct ttgtattatc tctatttttc
    30481 taaatttata ttactaaaat cttttatctt tgtatttgct aagacactct tcttagttga
    30541 ttgagaattt tttctatcaa aagtggcttt aacctttgca cctgataaga atttaccaga
    30601 accatttata caaccacctt cacacatcat tccttctata aaattacctt ctagctttcc
    30661 taaattagcc atagtcatag ttttcttgat ttctcttgaa ccagaaatct ttacaggttc
    30721 aaaattaaca ccaatacctt tttcagcaag ataattttct atagcctttg taagaccacc
    30781 agcagctcca aaacctcttc caaaaattga tgcatcatct atatcttcat ttgaacactt
    30841 agccaagtct atatcaaatg cctcaaataa tgccattatt tcttcaaaag taagtacata
    30901 atcaacagct ccttttaatt ctttcttagc tgcctcactc tttttggctg tacatggtcc
    30961 tatgaataca actttagcat ctggctcatg actttttata aatctaccac tagctatcat
    31021 aggagatact gtagaagata tttttcctac atgatttggg tatgtttttt ctatatagcc
    31081 aacaaatcct ggacaacaag aatttgtcat aaaatcttct ccattttcca ttctttcagc
    31141 aaattctaag ctttcgtgaa ctgtaactgc atctgctcca caagctgctt ctaatacatc
    31201 aacaaatcct agtgatttta tagcattttt tatttgacca tatgtaacat ttgcttcaac
    31261 ttgacctgtt atagctggag ctactactgc atacattttc tctttttgaa ctaattttct
    31321 agctacagga gctatcaaac tcttatcaga tattgctcca aatggacatg ctgacataca
    31381 tgctccacag tttaaacatt tctcttcatg tatcatagcc ttcatatttt ctctatcaaa
    31441 ccctaaggcg ttagttgggc aaacactctt acatggtcta acaacctctg agatggcatc
    31501 atattgacaa gcttttttac acattccaca agccttgcat aattcatgat ttatataggc
    31561 cattcctccg acatgtgtta tagctccaaa tttacaagct tctttacatc tatgtgctag
    31621 acatcctcta caaatatctg ttactgtaaa ttcatttatt ggacaactgt cacatgcagc
    31681 ttccaaaata tatataattt gttcattttc ttctatatcc attgtatcta aatctatctt
    31741 atcttgacct ggttgtaatc ccatacttac atttactctc tcagatatta tagctctttc
    31801 tttataaaca cagcatctgt atgtaggttt ctcacctttt attatttcat actgaatatt
    31861 atccattgct tctctggtaa ggttatcttc ttttccgagt ctagctattg cagttaaaac
    31921 atcatgtctt aatttgtgta tttgtgtttc aaattgaaac attttaatac cacccccgta
    31981 aatgatttta tacgatacca ttataacaca atatttcctt ttattaatat atacataaaa
    32041 tattatatgt ttaaatttta ttttatcgaa tatatatagt attttttcat cttattatat
    32101 aatattattg atatttctga aatttcacta tttttatttt tacttttcaa tcttatatat
    32161 aatatttttt gttatatatt ttaattttac tttttactta catacctttt tattacattt
    32221 tttgatatta aatttattat ttgtatttac atttccgtca aattttgtaa tacttctcac
    32281 tatataattt aacaattttt attaaattct aaaagtaatt aattttttta aaaattttat
    32341 ttgcttttat ttaaatttta tgttatatta atagaacaga cttatttttt tagtttgtat
    32401 tttttaataa tgcggaggtt ttcttataat gaaaaacgga atagtaaaat ggtttaacaa
    32461 tgaaaaagga tttgggttca tatctgtaga gggagaagat gatgttttcg tacatttctc
    32521 agctatacaa aatgatggat acaaaacttt agaagaaggc gaaaaggtta gctttgatat
    32581 aactcaaggt aatagaggac ctcaagctga aaacgtaaat agaatataat tatttaattt
    32641 aaatatatat attttagaaa aggagctatc gagggctctt ttttgttgtt tattatattt
    32701 atttttaatt acaaaaataa gaagttactt tagaaaaacg ttaaacttaa actaattttt
    32761 ttaaaataac ttcttatatt ataatacata ttattcatat aaaatactct atttaatttt
    32821 ctcagatatt atcaagcata actctcttaa gattttacag gctataactg tcgatacacc
    32881 tgtagtatca taatcaggac ttaactctac aatatcacaa ccaactatat ttatattaga
    32941 attttttata atcttaaaaa tctcttgaaa ctctctatag tttacaccac caggttctgg
    33001 tgtacctgtt cctggaaata cagatgcatc caatacatct aaatctatag taatataaat
    33061 attctttcca tttagcatat taactatctt ttcaaatgta tcaattccgc ctatttccat
    33121 gtatgtgtgt ttttcttctg tagcaaattt aaattcttct tttgtcccag accttatacc
    33181 aaattgaaat attttattat cacctacaat atcccatatt cttttaatta ctgttgcatg
    33241 agaatttttg ctattattat attcttctct caaatccgta tgggcatcaa aatgaattac
    33301 atatatatca ttgtactttt catatactgc tttaaaggct ggtaatgtga ctaaatgctc
    33361 tcctccaatc ataaatggca cttttgaatc tctaacaatc ttatatgttt cttgatagat
    33421 ttcctttaag acttgttctg tacttccaac actaatttct aagtctccat aatcacatat
    33481 attataatcc tctaagtcca aatctaaaaa aggactatac gtctcaagac cgtaaaattc
    33541 ttttctcata gagctacttg caaatctagc tccaggtcta ttagaagtag ttccatcaaa
    33601 tccaacacca aatactataa gattagattc ttcataattt ttgtccatac tcataaaggt
    33661 attcatatga tagaaattat tcttcatcta gcatctcctt tacatattga ggtaacataa
    33721 acgaacctaa atgtatatca ctattataat atttagtttt taaacttaat ttctcccacc
    33781 catttctatc ttgatttttt actggattaa gtttttttga agcaaatcca aacaaccagt
    33841 gaccagatgg gtatgttggt atatgtgctt gatagacttc tgatattgga aatatttgtt
    33901 ttaacttttt attagctctt ttcatctctt tagcattaaa gtcaaaatac ggactttcac
    33961 tttgatttac taaaattcca tcatcagtca gtattctata acaatcctta taaaaatcag
    34021 ttgagaaaag tccttcgcct ggtcctattg ggtcagttga atctactatt attaagtcat
    34081 atgatttatc atgtgcacat ttaacaaaat taacgccatc ttcaaaatat aaattcactc
    34141 tttcatcatc taatttacat gagcatatat ccatatactt cttagataca tctacaacca
    34201 ttttatctat ttcaaccata tcaatctttt ctatttgagg ataacggctt aattctctta
    34261 ctgtacctcc atcacctcca cctatgacta atactttctt tatgtttaaa tttgtagcca
    34321 taggaacatg agttatcatc tcatgatata taaattcatc tttatatgtt accatcatta
    34381 acccatctat tgtcagaaat tttccaaatt catcactatc aaatacgtct atcctctgaa
    34441 attgagattt tccttcaaat agatgtttat ttacttttat agaaaatctt acattttctg
    34501 tccattcttc tgtataccaa agttccatat aataatcctc actttctctt gtatgtttta
    34561 tactgcttct ggtttatgag taatcttacc taaatctttt tttgaatatt ttttgatttt
    34621 tgtagttaaa cctcttggaa tttctgtaga ctcgcttctt tcagatttta aaagttgctc
    34681 taataattca aaacttttcc atgggtctat atcaccacaa gtaaaaaaat ctgctgctgc
    34741 ataaccatat tcaggccatg tatgtattgt caaatgagat tcagcaatta taacagctcc
    34801 tgaaaccccc caaggattaa aatggtggaa tacagaatca acaattgtcg cctttgcatt
    34861 tagtgctgaa tcattcataa aattttctat aagacgtggg tctttaagta cgttttcatc
    34921 acaattatag tattctacta gtatatgtct tcctagtgtt tcaaatttca tttcaacccc
    34981 aactccttta tacttttaat aagttctatc tgataaaatc tatttaacaa acacttgccc
    35041 ttgcaaaata aaataattta ttttattact agtattctat ctaagttttt atcttgtaca
    35101 tctgtaagat atgcattgct attttttaag aaaataatat actccataat ttcttctgtt
    35161 atcaattctc ctggagcaat aatcggtata cctggtggat atgccattat tgattctcca
    35221 caaattctat ctatacatga attaatttct acactttcct ttggtgcata aaaagcttct
    35281 cttggattaa gtttaataat tggatttatt tgaaccatat taaattcatt taatgttgat
    35341 tcttttctat aaatctttgc aattatagaa agtgctttta ctaatctatc tatatctgat
    35401 ttatttgttc caatagacac aagtgccaga atattatatg aatctcctaa ttctacttga
    35461 attgaaaaat ttttatataa taaatcgtat acttcaaatc cagtcaaatt taattctttt
    35521 acatttatac acaattttgt ttcatctata aatttaacac ctttttgttt taatatttct
    35581 gtagataaaa cttttattcc atcaattttg ttcaatttag attttgcata cctagatagg
    35641 tttaatgctt ttgacagttg cttttcacca ttctcaacta gattaactct agcaccatct
    35701 atacttgcca taagcaaata agatgctgat gttgattgta gcatattgat tgattgaaga
    35761 accttttcaa agcttacatt atctctattc aataagagtg ctgaagattg tgtcaatgct
    35821 cctccagttt tatgtatact tacagctacc atgtcagctc ccaaacttat tgcagaagga
    35881 ggtaaatcta aatgaaatgg aaaatgtgca ccatgagctt catcaactaa cactaaaaca
    35941 ttatttttat ggcatagttc tataatactc tcaaggtctg cacaaactcc atagtaagtt
    36001 ggattaagga aaaataatgc ttttatatta caatcttttt ctatctcttt tctaactttt
    36061 tcaaaagtaa tatttaaact tatacctaat ttttcatcaa attctggttg tataaatatt
    36121 gggattcctc cacaaagtat taatgcattt atcactgatt tatgtatatt tcttggaagt
    36181 aatacttttt cacctggttt tataacactc aaaatcattg catgtattgc ttgagttgtg
    36241 ccattcgtta taaagaatgc ctcatcagcc atatatgctt gtgctagcaa atcctgtgca
    36301 ttttttataa tcccatttgg ggcagataca ttatccatag ttggtgatga atttatatcc
    36361 attttcatga gactttcacc tagatattta tttaatatag ctacacctct attttttaca
    36421 tgtccaggta catcaaaaca agctatgtct ttctctgagt attcctttaa cgactctaat
    36481 aatggagcac actcatagct taattcaact gcatttgcaa actcgctatc catgattttt
    36541 aaattcatct cctctctata ttcaaacatt tttaatattt attatttatt atttctattt
    36601 tttattttta cttttattaa actcatgata tttattatat taacattcca gcatttttac
    36661 aagtgttttt ttgaagttaa tcaaaaacac atatatcagt tatatcaata tttataaact
    36721 tttttatttt ttgttgttta tattaatttt tttaaaactt agtatttata aactttttta
    36781 ttttttattg ttttagcatt tttatttttt tgagttttag taagcttttg agtttactat
    36841 ttttaattta taagtatttt attactaaac ttttatatta ttctcatttt atatataaaa
    36901 agtcttggtt tagttgaact aaataatttt cctatttttg tattttaatt ttatattata
    36961 atttattaaa tttt
//
LOCUS       DBGJFK010000034        36082 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.034, whole genome shotgun sequence.
ACCESSION   DBGJFK010000034 DBGJFK010000000
VERSION     DBGJFK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36082
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.034"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(778..1062)
                     /locus_tag="ACOIAP_001986"
     CDS             complement(778..1062)
                     /locus_tag="ACOIAP_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638869.1"
                     /translation="MIVYNKNFYPNDIFSRLDFSKIKRQLKLIDNELSDFGNICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYGIVEEIEKLFKSQVGKFSISTYRN"
     repeat_region   1778..2666
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1982..2010
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            3024..3149
                     /locus_tag="ACOIAP_001987"
     CDS             3024..3149
                     /locus_tag="ACOIAP_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HGZ2638870.1"
                     /translation="MKIVSERFCHTDLKLTMNIYSYVLEEMYKKTSNNLSKILFR"
     gene            complement(3302..4174)
                     /locus_tag="ACOIAP_001988"
     CDS             complement(3302..4174)
                     /locus_tag="ACOIAP_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGZ2638871.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(4568..5146)
                     /locus_tag="ACOIAP_001989"
     CDS             complement(4568..5146)
                     /locus_tag="ACOIAP_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2638872.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(5203..5919)
                     /locus_tag="ACOIAP_001990"
     CDS             complement(5203..5919)
                     /locus_tag="ACOIAP_001990"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGZ2638873.1"
                     /translation="MRINKYIASCGIASRRKAEEIILEGRIKVNGSIVKELFFNVDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVKERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISGDEIRKFETGLKIEDYTT
                     APAKIKVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            6110..7195
                     /locus_tag="ACOIAP_001991"
     CDS             6110..7195
                     /locus_tag="ACOIAP_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGZ2638874.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYINSFIEKNMSNIDFLKTLIPHIQHSLDNVLKEASNFIGKISKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTTRNKADSIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(7349..8005)
                     /locus_tag="ACOIAP_001992"
     CDS             complement(7349..8005)
                     /locus_tag="ACOIAP_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638875.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNKKSDSDKSDNNNNSSQNQEKPNSSNPTPAPTPQDTSGGSDSSGNSQNSNNQ
                     "
     gene            complement(8220..9512)
                     /gene="lysA"
                     /locus_tag="ACOIAP_001993"
     CDS             complement(8220..9512)
                     /gene="lysA"
                     /locus_tag="ACOIAP_001993"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGZ2638876.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIKYFRAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSDYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIHLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHKAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEV"
     gene            complement(9530..10723)
                     /locus_tag="ACOIAP_001994"
     CDS             complement(9530..10723)
                     /locus_tag="ACOIAP_001994"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGZ2638877.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     regulatory      complement(10805..10973)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(11084..11701)
                     /locus_tag="ACOIAP_001995"
     CDS             complement(11084..11701)
                     /locus_tag="ACOIAP_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638878.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(11871..13571)
                     /locus_tag="ACOIAP_001996"
     CDS             complement(11871..13571)
                     /locus_tag="ACOIAP_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638879.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVFHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQNFITDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNELKDEVIEGTITRISPDVRGGNTNYYVTLDTNKGIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEGTGTDENTDSQDSENQGNV
                     "
     gene            complement(13876..14439)
                     /locus_tag="ACOIAP_001997"
     CDS             complement(13876..14439)
                     /locus_tag="ACOIAP_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638880.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKSISDYRE
                     DYYYDTMALIYLPMNIHRHSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(14600..15313)
                     /locus_tag="ACOIAP_001998"
     CDS             complement(14600..15313)
                     /locus_tag="ACOIAP_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HGZ2638881.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLINSQYELELRPTLQEGNLVVSLENVKLGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            15605..17269
                     /locus_tag="ACOIAP_001999"
     CDS             15605..17269
                     /locus_tag="ACOIAP_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HGZ2638882.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPENKTEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDLPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPAK"
     gene            complement(17376..18275)
                     /locus_tag="ACOIAP_002000"
     CDS             complement(17376..18275)
                     /locus_tag="ACOIAP_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HGZ2638883.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEQNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELNIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVYIECADSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(18302..18940)
                     /locus_tag="ACOIAP_002001"
     CDS             complement(18302..18940)
                     /locus_tag="ACOIAP_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HGZ2638884.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KVGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKSTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(19280..20278)
                     /locus_tag="ACOIAP_002002"
     CDS             complement(19280..20278)
                     /locus_tag="ACOIAP_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HGZ2638885.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYNYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KEFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADFIQNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(20376..20951)
                     /locus_tag="ACOIAP_002003"
     CDS             complement(20376..20951)
                     /locus_tag="ACOIAP_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638886.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            21268..21531
                     /locus_tag="ACOIAP_002004"
     CDS             21268..21531
                     /locus_tag="ACOIAP_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638887.1"
                     /translation="MIKNTKQITVEVNEILLQEISKITNDENNILTDLINESIVNYIL
                     ENKKHNVEDKDLEEVIKFYKKENTEKTKSAARAIAEAKTHTLY"
     gene            complement(21951..22328)
                     /locus_tag="ACOIAP_002005"
     CDS             complement(21951..22328)
                     /locus_tag="ACOIAP_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2638888.1"
                     /translation="MTITKIPPAELKVMKFIWISDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            22669..23781
                     /locus_tag="ACOIAP_002006"
     CDS             22669..23781
                     /locus_tag="ACOIAP_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2638889.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDKETGKRKQKNMGIFDKKREASKRL
                     NEVKESLYKDGFLVPNEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPIHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDGIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSIRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVISKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(23978..24430)
                     /locus_tag="ACOIAP_002007"
     CDS             complement(23978..24430)
                     /locus_tag="ACOIAP_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638890.1"
                     /translation="MVKKRLVAIVMSLAMISVGNFSYAHSGGHNSSGSHHNKNKSELT
                     YYYYCGGHSAHQHNKGFCPYASAKSNSGVTISSAHNEKNHKKFFSEKEYNKGYEDGCK
                     GLYNLSFTEAKSEDSYEKGYLIGYNEYKAKKVYDVIKKMLDIPMLASI"
     gene            complement(24625..26250)
                     /locus_tag="ACOIAP_002008"
     CDS             complement(24625..26250)
                     /locus_tag="ACOIAP_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGZ2638891.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLENKEIQEQLAKMYGKDK"
     gene            complement(26588..27607)
                     /locus_tag="ACOIAP_002009"
     CDS             complement(26588..27607)
                     /locus_tag="ACOIAP_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HGZ2638892.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKDVI
                     KNAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(27604..28173)
                     /gene="mocA"
                     /locus_tag="ACOIAP_002010"
     CDS             complement(27604..28173)
                     /gene="mocA"
                     /locus_tag="ACOIAP_002010"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070567 - cytidylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032324 - molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HGZ2638893.1"
                     /translation="MINAVIMASGFARRMGVNKLLLDYKGCSIIEHVFRVVNKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANVGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDICGNPVIFPYGKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKIDYERIGGKL"
     gene            complement(28291..29013)
                     /gene="yqeC"
                     /locus_tag="ACOIAP_002011"
     CDS             complement(28291..29013)
                     /gene="yqeC"
                     /locus_tag="ACOIAP_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium cofactor biosynthesis protein YqeC"
                     /protein_id="HGZ2638894.1"
                     /translation="MKLSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIITTIDGTIIPSICHGIIVCGSHINNENKLVSIDSSILDEIVDKFDLV
                     LIEGDGSKRKKLKGWNTKEPVVYHKTTKTIGILDITSFGMDINEENIHRVEMFKKIAN
                     LNTKSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIKNI
                     KECESEIEIFYGSVKQKFCARY"
     gene            complement(29196..30473)
                     /locus_tag="ACOIAP_002012"
     CDS             complement(29196..30473)
                     /locus_tag="ACOIAP_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HGZ2638895.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGTLNVPMSPVFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCIKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFANDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(30612..32918)
                     /locus_tag="ACOIAP_002013"
     CDS             complement(30612..32918)
                     /locus_tag="ACOIAP_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="HGZ2638896.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDRVRFVGDE
                     VALVAAEDEKIALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     NNNIVSKEFFEFGDVEAKLKESDLVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFALDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTSGKAAEGEILSCELKQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGILKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPRFDKD
                     GRLLTNSFLQYKVPTKKEVGNILVDFAENFDSGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRIRELPMTFEKVYMGMKNNNKQL"
     gene            complement(32911..33705)
                     /locus_tag="ACOIAP_002014"
     CDS             complement(32911..33705)
                     /locus_tag="ACOIAP_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HGZ2638897.1"
                     /translation="MVTIKEYSVPQSLEEAYKILTSKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEMDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGMLELNEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSILNSAMLKENNTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(33812..35170)
                     /locus_tag="ACOIAP_002015"
     CDS             complement(33812..35170)
                     /locus_tag="ACOIAP_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGZ2638898.1"
                     /translation="MKAKSTSKFELDGMPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALIFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVAGKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNQINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLIFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKIVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLERFPKFVETLLADSSVVSGAMVAIIIQALYMVKFPKNKNGKVEDKNK
                     SL"
BASE COUNT        12031 a         5963 c         3745 g        14343 t
ORIGIN      
        1 tatttacttg gtttattatt gtatttgaaa aaatttatta aacctaaaag tttttcaaaa
       61 tttatgatgg ttttatcact atcttcagtt gctattgcaa agttttatat gttgagaaaa
      121 actaatgaaa attataaatt ttatcgatta gtaatattgt tttttattga ttgttgttta
      181 ctttttattt ttcaatcatt taagctaata aatcttacta taagtatcat tagtttatat
      241 ttattctttt ttatctgagg aatatggtta gagatgtttc ttacaaaatg ttttatttga
      301 taaattcgtt aaaaaaatag gtattatagt ggtagatatt tgttgaagtt tatgtattta
      361 cccttacaat tcacattgta taatctagac actcaaacaa tttaaagttt aattcatttg
      421 atatatggaa tcggacttta tatattttta ggttatgttt atataaaagc caaaaatatt
      481 ctgttttgtt ctataattca taatttggtt aatagtttag atattatttg taacttttct
      541 aaaataacgc ttagttatta tattatttta gaaatactta tatttatatc attgtttttt
      601 cttcatcttc tctttacaaa aaaatataaa acaaatataa aaatataaat tagggtatat
      661 caaaattaat aaaaataata tatacttatt tgaaaaaggt aacaactctt tttagttgtt
      721 acctaataat ttatctatac tttagtatta aatcttttaa tttctaactt tcaagtatta
      781 atttctgtat gtagatatgc taaactttcc aacttgagat ttaaataact tttcaatctc
      841 ttcaactatt ccatacacct tgttttcata ctctaaatca taatacacat ttatctcacc
      901 tatactattt acacttattg tataatgctc tttctctatt atacatatgt ttccaaagtc
      961 tgacaattca ttatctatta attttaactg tctttttatt tttgaaaaat ctaatcttga
     1021 aaatatatca ttaggataga aatttttatt gtatacaatc atttcatcca ccccttatca
     1081 ttctatttat gatactttat accctaatta ataatgcatt aatcatattt ttccatatta
     1141 ttcaaatttt cttatataaa aacagattgc aaatcgattt ttcaatgttt tatattatta
     1201 tgtttagatg tatgtcagta aaatgaaagt atgagttttt atccacagat tttatgtaag
     1261 ttttcaatac ctcataaaat aattatcttc cacaataaaa gtatggtgct tatataaaaa
     1321 tgctcttttt atcaaactat acttttttag gagatagtta aaacatgtaa aatcatctag
     1381 ctaggagagt tttattatgt ctagaattaa tgtatcatta gaataaaaat taaagtagtt
     1441 gagtcatatt ttttaaagag tttaatttat agtagaaaaa cattttattt tatgtaatca
     1501 aattagagta tgtattctta aatataaata aaatgtataa attaattaga gaacaaggag
     1561 gtaaaataaa aaaagaaagt aagttaattc aattatatta gataattttg gaattgaaag
     1621 tttaaaataa taaaaacaaa ttacaactgg acaatacata cttaaaaaag ttacaaatag
     1681 aaataagata ataattatat tatcacataa ttaagataaa tataaagtga ttcaatcttt
     1741 actcactgaa aaaacttccg ttgtccaata gtgaaacatt taaattcaat atagctaata
     1801 taaaactata taaaacgaaa gttatctctt aataaatgtt caatagacta tgctttatat
     1861 accacttagt taatataaaa cgcaactgca agagtagaaa taacattaat aatttcactt
     1921 acataccact tagttaatat aaaacaatac aaataagatt ttgttttcat atgattcaga
     1981 aatttacata ccacttagtt aatataaaac tgtggattac cagttcctaa aaaactaaaa
     2041 gaaaaaatat ttacatacca cttagttaat ataaaaccta tcattagatt gtgaacctat
     2101 ctctattttc ctatatttac ataccactta gttaatataa aactaaattt tgtattcttg
     2161 acattgacat ccaatatata atttacatac cacttagtta atataaaact gatagagaaa
     2221 cttgaaagcg aagatgtgct attaaattta cataccactt agttaatata aaacggaaac
     2281 ttgtataatc acaataacta gcttcgtttc atttacatac cacttagtta atataaaact
     2341 tcactttgat ttaactcatc tcttttcaca cctttattta cataccactt agttaatata
     2401 aaacaatgct gataatagta aaattagctc aatttctcga tttacatacc acttagttaa
     2461 tataaaacct gtatatttac aagttttata taaatattag tttccaattt acataccact
     2521 tagttaatat aaaacccagt tgaaaggtat cctattatct gcatttctta aatttacata
     2581 ccacttagtt aatataaaac ttaactaaaa cttgaaaacc ataatcttta agcttaaatt
     2641 tacataccac ttagttaata taaaacccta aaataaacgt agaatttcca atactcacac
     2701 atatgcaatt ctcttaaatt tgcagtgagc gaacagtagt gcaaatgata atgtttatca
     2761 atcactatca ataccttaca tttcaatgct taaacatatt ttcttcaaaa aatcgaacac
     2821 tgcaaaattt ctatatcttt attatatcat aaatatatta tatatttttg tatacaatta
     2881 ctctatcatc aatagtattt ataacttaga tttcaaataa taaaatcata gttatataat
     2941 gtattaaaaa tacctaatga caaatgaaaa tacataattt aagatataca ggtgctagtt
     3001 tgttacattt ggtaggaact aatatgaaaa tagtttctga aagattttgt catacagatt
     3061 taaaactaac tatgaatata tattcttatg ttttagaaga aatgtacaaa aagacctcta
     3121 ataatttaag taaaatatta ttcagataaa caaaaaactg actgtcagtt aaatgtcagt
     3181 taaacctaaa aaaggaattt gccagttaaa tgccagtcag ttattttata atatctttgc
     3241 ttaaataggg ctagatttga acacatttta actcttgaaa ctatttatta atatacaaac
     3301 tttactcata cacagaatat cttttccaaa tctgctctaa atcatcaaaa tgttgtttaa
     3361 tatcttcttt ttctttcatt ccaacagata tagcaagagc atttgaaata ctaagagcag
     3421 gaactagaga atctacaaac gaagccatat tacttttaac taaaagagta ttgtctgcaa
     3481 gtgatgctac tggtgcaaat aaactatctg ttaatgatat tacatgagct cctttttcct
     3541 tagcataatt gacaatttga taagattttt tagaataacg agggaaacta atagcaacta
     3601 ttacatcttc ttcatttatt cttacaatct gctcaaaagc atctcccata tccattctaa
     3661 ttatatgaac attgtcaagt attatatcta agtaaaaacc taaatattga gctactacaa
     3721 aagaacttct cattccaagt atatatattt ttctagctct taaaagttta ttagaagctt
     3781 ctttaaatgc tctttcatca atttcttcta atgtagacct gatattatct atgtcactct
     3841 ttaaaacttt gtttagtatt gcaaaatcat cagaataatc atgtgccatt tcaactcttt
     3901 gtactgtagt tagtttattt tttatgagtt cttgaagtgc agcttgtaat ttaggatatc
     3961 cactataacc taatgcattt gcaaatctta caactgtaga ctcgcttact cctacagttt
     4021 cacccaattt acatgcagtc ataaatgcaa ctttatcata attatttaaa atgtattgtg
     4081 ctataagttt ttgaccctta ctcaatctcg tatattgaga ttgtatattt gatatcaaat
     4141 gtttactgtc cttcatttca tttgtttctt ccattttttt ctccttttag ttatataaac
     4201 tattttgttt tattaacact gtctttttct ctaaaaattt tattttttat ctcaatttca
     4261 tcttagtttt tatcatagct tcttaaactc ataaaattct aacttttctg taccttatac
     4321 ttcacatagt attttcgatt aaatttatta taccatcttt ccttgcattt tttaatattt
     4381 atccaatatt tcttttaaat ttttcaattt ttactcattt aaaagttatc tatcttattt
     4441 tgcatattta gatgtatatt ttgttttgag tataagttat tgtatactta ttatttaaag
     4501 tatttttaat aggtcacact atatatatta actcttaata gaatcttgtc aagtttttta
     4561 gtatttatta tgcttttttc ttttcaatta aaatcaattg tggtgggtta ttgacttgat
     4621 ttaaaaactt agattctaaa acattaaatt catcttgatt taaattatta acaaggttat
     4681 atatacaatc tttttcttct tgacctccat catgtcctgt atatatggca atgcttatta
     4741 ctccattttc ttttaacatt tctaaactca actttatagc ctttaaagtt gtatctggtt
     4801 ttgttataat tgaatgcttc gctcttggaa gataacctaa attaaataaa acacatgaaa
     4861 cttcttcttt tatatattga ttcatttttt catgcccatc aaatatcaat tttactctat
     4921 ctgtatatcc ttctttctct aatttttttc ttgtagactt tattgcttct tcttgtatat
     4981 caaaagcata tacaaagcct ttttctccaa ccttctcagc tagatacctt gtatcatacc
     5041 catttcccat agtagcatca attactatat caccttcatt tataatattt tctaaataaa
     5101 atttatttat atctgtaatt ttagttaaat actttgcata tgccataata ctatttctcc
     5161 ctactattaa ctttatttct tttttctcaa tttattttta tcttatttta ttgattttaa
     5221 atattttatt tcatcttctg ttaggtatct atattctcca actttggtgt cttttaatac
     5281 tattttcccc acagaaatcc ttcttaagtt taaaactgga tgatttatag ctttacacat
     5341 ttttcttact tgtctatttc ttccctcatg tatagttatt tcacacactg aataattttt
     5401 ttctttattt tctttagtta cctttatttt ggcaggtgct gttgtgtagt cttctatttt
     5461 tagccctgtt tcgaattttc ttatttcatc accacttata attcccttca cactggctac
     5521 atacgtttta tcaatttcat gctttggatg ggtaagctta tatgttaaat ctccatcatt
     5581 agtaagtatt aataacccac tagtttcata atctaatcgc cctattggat atactctttc
     5641 ctttacgtct ttaagtatgt ctattacact tggtctatta aattggtctt ttactgtagt
     5701 tatatatccc tctggtttat tcaatactat atatatataa ttttcacttg gctttacttt
     5761 tttattatca aattctacta tgtctttttc ttcatcaaca ttaaaaaata gctcttttac
     5821 tatacttcca tttaccttta ttcttccttc aagaattatt tcttctgctt ttcttctgga
     5881 agctattcca caagaagcta tatatttatt aattctcata cttaatcctt ccttatctta
     5941 aattatgtgc tgtttaatat ttttatcaat attaattttg ctacattatt atactatact
     6001 agaccttaat taaaaacaag ccaaaaaatt atttaatttt cctaaataat tgtaatttct
     6061 tttcacatac tattaatatg caatatctga ctagatacta tttaaggaag tgattattat
     6121 ttcaaaagaa aatataaaat attatttaat agtcgtgttt attggaattt tattttttaa
     6181 atttattaat actccatcag actttatatc tagtattgaa ggtttcttaa agttttttag
     6241 cccattttta ttagctattt tacttgcttt acttttaaat ccacttgtga tgctttttga
     6301 ggtaaaattc aaagcacata gacttttagc tattttttta tcttatatat ttataggttt
     6361 tattttagcc tttgccatta ggttattgat tccatcaata gctaatacat taaatagatt
     6421 gataaatgaa atgcctatgt atactgatta tataaatagt ttcatagaaa aaaatatgtc
     6481 aaacatagat tttctaaaaa ctttaattcc tcatatccaa catagtttag ataatgtatt
     6541 aaaagaagca agtaatttta ttggtaaaat ttctaaaaac ttcttaattt atacacttag
     6601 catatcttct atgctattta atatgacaat gggatttata ctatctatat acattatata
     6661 tgacaaagaa aaaattgcat tgggatttaa gagatttcta tattcttcta ctactagaaa
     6721 caaagcagat agcattatag aattttttag gactactcat gatattttct atgattattt
     6781 acttggtaga atattagatt ctcttattat tggtataatt gcatttttag gatttcaatt
     6841 tgttatcaga atagaaaatg ctttattttt agcttcaata atattcttag gtaatataat
     6901 cccatatttt ggtcctttta ttggtgcaat ccctccaata gccatgacta tattatatag
     6961 tccacaaaaa actatatggg tcattgcatt tctatttata ttgcaacaat tagatggaaa
     7021 ttttatagaa ccaaaagtta tgggtaatca agttggtata ggagctatct gggtaatatc
     7081 tgctatttta gtaggtcaat ctctatttgg tttcatagga gtttttcttt cagtgccaat
     7141 agctgctgtt gtaaaaactt acgttgataa atatatagac aatcggttgc aatagtttat
     7201 ctctactgtt atttagcttt tagtttaaat tttaactgtt atttgtcaaa ttatttttaa
     7261 aaaaatacct cttagtaaga aaaacttact aagaggtatt ttttataata tatattttgt
     7321 tcatcaaatt tatgtatata ttttatactt attgattatt cgagttttga gaatttccac
     7381 tactatctga accaccacta gtatcttgtg gggttggtgc tggtgttgga ttactactat
     7441 ttggcttttc ttgattttga gaagagttat tattattgtc agatttatca ctatctgatt
     7501 ttttattatt tttagaacta gatttattat ttttactact tccactataa gaagattttc
     7561 ttgcatctga ttcaactcta tacctatctt ctccagctgt atcttttgcc tttttctttc
     7621 tttgttcctc tgcttcattt tgttcttttt ctaatttagt taactcttct ttctttttag
     7681 ttgcctcttc tttaataaca gaggaaccat ttttgatttt ctctataagt ttaagttcct
     7741 tgattgcccc ctcataattt tttaattctt caaactctgt catatttgac attctcatag
     7801 cttgcatata catagctctt gcattctcat tagtactatc ttcttccagt gcagaggata
     7861 atgattccat agctttttta tagttatgtt tttctaaata cgtttttcct tgctctacta
     7921 aatttatttc atctttttta ttaaatgaac atcctacaag aaatatagat aatatcgata
     7981 ttaataaaat tactcttcct ctcattaaat ccctccttgt catatacttt aaattttatc
     8041 ataattataa agtttttaaa atattttata tttattacaa gaaatttgtt agtaaaacga
     8101 aaaataagca gatatgctac gaacaatata ataaaccaaa aattaattta gatatatatc
     8161 atagcaaatc tgcttataat aaactttaat attcaatttt tactatatgc ttctccattt
     8221 tatacttcta aagctaataa gtcctcatag ctttgtctct tacaaattat cttatcattt
     8281 ccgtcaaata ctgatactac tgctgccctt ggtattttat tataatttga agacattgaa
     8341 tatccatatg caccagttga tgttgttata agtatatctc cacttttaat gtccattata
     8401 tttatatctc caattaatat atctccactc tcacaacatt ttccagctat tgttacatga
     8461 ttcatagcct tgtgattaat tttattcaca atactacact cataactagc ttggtacaac
     8521 gaaggtctta cattatctgt cataccgcca tctacactta catataccct aacatctttt
     8581 atatctttta tagaacctac tgtatacaat gtacttcctg catttgcaac tattgacctt
     8641 cctggttcta ttaccaatgt aggtacttct attccaagct ctttacatga agtttctgct
     8701 ttagtgatta tagtttcaca aaactctttt atagttttag gtttatctcc ttcgctataa
     8761 taaactccaa cgcctccacc taggtcaatc tctgttagat gtatgttgaa tttttctttt
     8821 atttctttta ctaagttcat cattatatct actgtatcta tgtatggttc tacatcaaat
     8881 atttgtgaac ctatatgagc gtgaagaccc acaagtttga tatttttata gtcacttaat
     8941 ttttctattg ctctaaataa atctccattt actaaagcaa atccaaattt agaatctatc
     9001 tgtccagttt ttatataatc atgtgtatga gcttctatac caggagttat tctaaaatat
     9061 atctcttgag ttttaccttt atcttcacat aatgcttcaa gtaaatctaa ctcataaaaa
     9121 ttatccacta caaatttacc tacacctaaa tctaatccca tgtttatttc ttctttagtc
     9181 ttattgtttc catgaaagaa aactttttcc ataggaaaat ttgatttata agctgtatac
     9241 aactcgcctc ctgaaactac atctagacac atttgttctt catttataag attacacata
     9301 taaagaggta aaaaagcttt ccccgcataa gcaaccttat tttttccctc tctagctcta
     9361 aaatatttta tatattctct acaattttgt ctaactaaag cttcatcaaa tacataaagt
     9421 ggagtttgat attttttact aagttctaaa caactcactc ctccaatata taattcatca
     9481 ttatttacag tcatagttcc atgaagtttc ataatagcct ccccaaattt tatatattaa
     9541 atacttctgc tattttctct atagctactt gcttatcatc agaatttata gcacaagtta
     9601 tacgaatttc tgatgtagtt ataagtttta tcattatacc attttcattg aatatcttaa
     9661 atactttagc agcaactcca gaagtatttt tcataccaag acctactaag gaaaatttag
     9721 tgatattatt atcaataact acatgttctt catctgtata tttagatact atctttttac
     9781 attctcccaa ttcttctttt ggaactgtaa atgatacact tatcttatct aaaataggtg
     9841 cagtttggct tatcatatct acacttatac ctatagttgc tatatcttca aataagctag
     9901 atatattctc tgctttaaaa tcttttattg ttatagaact gtcatcatca ctagtagcta
     9961 atcctgttat tactttatcc tctaatttca tgtcttttcc ccctcttata tatgttcctt
    10021 tttctgtacc acatgtacgt ccaacataaa tttcaacacc atatttttgt gcaagctcta
    10081 tacttcttga atgcattact tgtgctccta aacttgctaa ctcaagcatt tcttcatatt
    10141 caatctcatc aagcttgcta gcctttgaat attttcttgg gtctgtaaaa taaattccat
    10201 caacatctgt atatatctca cattttccat ttaatttaac tgcaagagct acagcagatg
    10261 tatctgaacc acctcttcca agagtagtta catcaccatc ttcgttgatt ccttgaaatc
    10321 cagttactat cacgacattt ccttcatcta aactattttt tattctgttt acgtttatat
    10381 catcaatctg agactttcca tgaagaccac tcgtttttat atttaactga taagcattat
    10441 aacttatagc tttacatcca agtgcattta atgctattga taataaagat gctgaaatca
    10501 tttcaccagt agacattaaa gcatctaatt ctctcttact aggttcatta ctcaattcct
    10561 ttgccaaagt tatatattca tcagtggatt ttcccatggc agacacaact attaccattt
    10621 gtggattttc ttttcttcgt tctattatgt tttctgctat tgattttatt ttttcagtat
    10681 ctgctactga acttccgcca tatttttgga caattatact catgctttct ccccctcaag
    10741 ctaaattttg ataaataaaa acgcccaaag gtatactttg gacgtgtaaa tttcatagac
    10801 caagtaacct tgtagctcac cactttaaaa gtgacagcct tatgcatatt ctgcataagt
    10861 ccagaaaatt tgtccgtcaa caaaatttct tcggctatat accctttcat caattatcaa
    10921 tgcttaccag ctcctattga atactattga atacagctac ctctacccta ggctcattat
    10981 ttttaattaa tttattaata tagttttatc atattctata taatattgca acaattattt
    11041 tacaaaatgt ggcaaatcaa tagttttctt ttctaaaatt agcttatata caattaaata
    11101 gtttatttaa tcccaaatct ataaaattta tactatactc attatcatat ctctctaaat
    11161 catttaattc agataagtta tctggtgtaa ctaccaaaac gtttggcact ttaaaaaatg
    11221 gaattgtaga tttatctatt tttttagaaa gattttcgta tttagaaatg tctatttcat
    11281 tatttaagtc aacatctact agaacttgct ttatattacc aaattggtct gtatattcaa
    11341 taaataaatc gtatttaaca tcatctacac taacatttcg gtaaaatctt tttacatcac
    11401 aacctgcagt attgattcta acaactaatt ctgatcctac tagagccttt attaaatcat
    11461 ctcccttaaa aagcttacta ccatttaaat agtatacata agagaggtct ttataattat
    11521 aataatctac atcacaagga tattttttta gtgtatattc actacacatt tttctcaaag
    11581 tttttttaaa atttttttta ttgtatcttt tttggtctcc ataaattttt ctaaattgag
    11641 actctgtaac acatctaacc ctgctaatta aaagtaatat ctctttttcc atattcgtca
    11701 tagtacattc tccttgaagt attatttgca aagttgtact aatattatat taattttatg
    11761 acattaaatt tacaaagaat taaaataaaa tagctaattt ttatagaatt aaattctata
    11821 aaaattagct attactatgt taaatattgt tataagtctt tttatttaaa ttatacatta
    11881 ccttgatttt cagaatcttg agaatccgta ttctcatcag ttcctgttcc ttcttttgct
    11941 tttttatctt caaagtttgc aatatttaga ttatcaaatt ctgacatttc tattacacca
    12001 gattcttctt ttgaatacga tattttgact ttatcaccaa cctgagtcaa tggcaattcg
    12061 ctagatactt ttgaagtagc cctaaatatt atacctttat ttgtatctaa agttacataa
    12121 taattagtgt taccacctcg tacatctggg cttattcttg taattgtacc ttctattacc
    12181 tcatctttta attcattatc aagtttcaaa tcattccctt tagattctaa tgcatcttta
    12241 tagtttctta atgcttcatt cttatcttca cctattccaa gtacattata atcttcaaca
    12301 gatacaaatg caactctctt aacaagacca gccttatctt ttaatgatga tacatatgtt
    12361 ggctgaccca atatattata cattacaggg aatgttgctt cataattttt ttcttgaaca
    12421 ttaccttcag ctgatttcat tgcagccgtt tcagtagctc ctggttgttt atataatcta
    12481 gcttcttttg ttctagaatc aactaacata aatccaattg tagattcatc tccacctgag
    12541 gatgttatac ctgtatacca ataagaccta ttatcattac cataaactaa tgatgtacct
    12601 tctgttggta ctaaaactcc tttttctgat ataacagaat ttaaaaatcc attaacataa
    12661 acgccccagt ctttaatctg gtctgttata aagttttgtg gttgtattct atccacccat
    12721 ttaggtgtgt ttttaacatc ataaacattt atttttccag tttctgcatc aacagtggct
    12781 attcctgtgg catttgctcc tccatatcca attttatgtt catataaact tacaacccaa
    12841 taaggtcttc cttcatcatt tatttcaaga gtgaaatctg tcataccaac atttacaata
    12901 ccatgtatgt ataaatgtct ttgtaaatct tgatgtaaat aggcttctgg ttggtaaact
    12961 atctttattg gctttccatc tatttcttga actaattgga catcttgagg attactagct
    13021 gatactttta cataaccact tgtaccactt agagatgtta tccatttaat tatgtccctg
    13081 tgaacaagag gtgctaccca gtacagctct ccatctacat tttgtatatg aaattttcct
    13141 aatttggata cactccctat tgcaggaact tctccaagct ttttatcgcc caatttcatt
    13201 gccatatctt catctacaag acgaatgtca tttacactga cagggctaat gtcatcagta
    13261 aatttacttt cagttacttt tcccaatagt tctctatatg attttgcatg aaatacagga
    13321 gtagaagtta taaagggaac taccacaata tacacaagca aagctattgc tattgaaaaa
    13381 ttatatttag ccattttaga tgctctttca tttctatcta acatcatatc tagtattcct
    13441 gctacaacaa agaaaattat tcctactgaa aataaagatg taaaatctaa tcttagtaca
    13501 ggtaatttaa taaatgcata aattattaca attattaatg caactccata tgttttaaga
    13561 tatcgtttca tttaatactc ctctctaaaa aatgttatta ttactattat atccatatat
    13621 ttacaaaaaa taaatattta tcatatttat tatgtattaa gatatcttta tatatttata
    13681 gttctaccta ttcaattata tgtaatatat atatccaaaa atattataaa aatacaaata
    13741 atagcagaaa tttaaaaact gaagaaagta ttctaactaa gatttacaaa ttcttaatcc
    13801 tatcgaagtt aaactactat cttcagccta attgtctagc aatatttttt atatgaaaaa
    13861 ctctaaatca agtttttaaa tgtttgcgat ttttgataca taagaatgtt gtctagaatt
    13921 atattctgat aataaacctt catactctaa ggttaaacca gataaattat aaaaatcatt
    13981 tggtgttact tcaaatgctt gtttatttaa aatgtctatc tcactttttt ctaacatgtc
    14041 agcaacaaaa tttgaacata catatttata ttcagagtgt ctgtgaatat tcattggtaa
    14101 atatattaat gccattgtat cgtaatagta atcttctcta taatcactaa ttgattttat
    14161 atttttatat agattttcat attgtaaatt atctacttct aacgaatata ccctacacac
    14221 agtgtttttt cttatagcat ataatccttg atttatattt tcttcaacaa aacctccaat
    14281 aaagggattc cttggattta gtctcccaaa agaatacatt ggttttagat tttcatttaa
    14341 tgatattgac acatgtgtat acagtttttt acttatattc cttattaagt aagataatat
    14401 agttcctgta tatgttgtta caatatagac tttattcatc atttcccccc aatctagtaa
    14461 ctaaataata ttatacattt acaatttaat atcataagat attctaacat aataaatgta
    14521 gttttacaaa ttttgatttt aaggtacttt aacattatat aaaatataat aaaaatataa
    14581 atataagttt tctatatttt taaccaacag acgttttctt caaattaatc agatgattta
    14641 gtatatcttg aaccttccca gaatccttta aatatcctaa tgccccgttt atttgtgatt
    14701 ttaaatctat ttctacttcc atatctaagt caacatttcc tttttttata gatatatttt
    14761 taagcgttat tgggtaaaga taactttttt ctaaagtaat cttatttcca ttaacctcaa
    14821 atggaacttt tttattgtag ttacttaata ttttttctaa cattttatca cttagcttaa
    14881 attttccaag tttcacattt tcaagactta caactaagtt tccctcctgt aaagtaggtc
    14941 tcaattcaag ttcatactga ctatttatca aaccaaatac cttatatggt cctgctacct
    15001 ttattttacc atttttcatt tcaacaaaat tattttcaag ttcattaata ccatgtttct
    15061 gcatcaatgt atagattaaa tttttaaact cttcctctga aacagatatt tttccaacca
    15121 ttctaagtgg attttttact acttccatag aatttatata tgaacctttt gataaatatt
    15181 cttcatctat aattttatta ttttgtgaac taacatcata tctttctttt ggtgtcaaga
    15241 tatatacaac aatacctgca agtactaaaa caataacaat taaacttaat aaaatctttg
    15301 caacctttcc cataatcgtc tcctttacaa atctgtcaac agatttaaaa taaatttaga
    15361 taactaactt cacataatat tcttaacaat atacatacta taatacagtc ttttaaaaat
    15421 taattcaact aatctcattt tttgtaaata aactgtaaaa acatgttttt agtataaaag
    15481 ttaatatttt gcataatact cttaattaca cctttatttt tttctaatct tggattaaaa
    15541 ttaatattat gcaatacagt gtagtgttct gtattataat caaattaaat aggaggtata
    15601 gaatatgtca aatgaaacga actcatctaa ctttataaaa aatattatta taaacgacct
    15661 agaaacagga aaacatgaca gtataataac tcgttttcca cctgagccaa acggatattt
    15721 acatattggt catgcaaaaa gtatatgtct taattttgga ttagctaagg aatttaatgg
    15781 aaaagctaat ttaagatttg atgatacaaa tccattaaaa gaggatgttg aatatgtaga
    15841 atccataaaa gaagatgtca agtggttagg atttgattgg aacgagttaa attttgcatc
    15901 taactacttt gatgaaatgt ataagagagc tttaatacta ataaaaaaag gtaaagctta
    15961 tgtatgtgat ttgacacaag aagaaatgag agaatatcgt ggtactctaa ctgaaccagg
    16021 aaaagaaagt cctcatagaa acagaacgat tgaagaaaac cttgatttat ttgaaagaat
    16081 gaaaaatggt gaatttaaag atggtgaaaa aacattaaga gccaaaatag atatgtcttc
    16141 tccaaatata aatcttagag acccaattat atatagaata tctcattcaa cgcaccacaa
    16201 tacaggagat aaatggtgca tatatcctat gtatgctttt gctcatccaa ttgaagatgc
    16261 aattgaagga ataactcact ctatatgtac tttagagttt gaagaccaaa gacctcttta
    16321 tgattggttt gttaaagaat gtgagatgga aaacatacct agacaaatag aatttgctag
    16381 acttaatata aataatactg tcatgagtaa aaggaaatta aaacaacttg tagatgaagg
    16441 tattgttgat ggttgggatg atcctcgtgt tcctacaata tctggaatca gacgtaaggg
    16501 atatactgca gaagcattgc gcaatttctg tagtgaaata ggtgtatcaa aagtcaactc
    16561 tacagtagat agtcaaatgc ttgattattt cctaagagag aatttacaac caaaggctcc
    16621 tcttactatg ggagttttaa gacctttaaa acttattata actaattacc cagaaaataa
    16681 gactgagatg cttgaaatag agaataatgc taaagatgaa tctcaaggaa aaagattagt
    16741 tcctttctct agagaattgt atatagaaca ggatgatttt atggaagaac ctgttaagaa
    16801 atattttaga tttttcccag gaaatgaagt ccgtttaaaa ggtgcttatt ttgtaaaatg
    16861 tactgatgta attaaggatg aaaatggaaa tgtagttgaa atacatggta cctatgaccc
    16921 tgagactaag agtggctctg gatttacagg acgtaaggta aaatctacaa tacattgggt
    16981 tgatgctaaa tcagctatac catgtgaatt tagattgttt gaaccattaa ttcttgatga
    17041 tttacctgaa aacgagggca agcatttctt agaacaaata aatcctaatt cattggaaat
    17101 attacaaggt tttgttgaac ctacacagat aaaagatgct aaaccttttg ataaattcca
    17161 atttgttaga aatggattct ttagtataga taataaatat acaactgatg aaaaatttgt
    17221 atttaataga atagttcctc taaaaagttc tttcaaaccg gctaaataat cttacaatca
    17281 aaaaatgaag acttaaaata taaattactt ctactataaa gaaacttagt tagaagtaat
    17341 tttttatttc agccttcatt atttacttta aatgattaac ttttttcact acagattccc
    17401 ataacttcta ttccatcttt tatacattct atgttaaggg gaaaatctgg tcctttttct
    17461 ccatcaatat ccgttataag tgaatctgca cattctatat acaccttttt agttttaaag
    17521 tatagtatct catttccatt atattgatct aaataatcac ctctaagcac acttatcaaa
    17581 actggtattg attttggtat tggcattcct ttaaaaataa tcacatccag atacccatca
    17641 tctatttcag ccttatatgc tagatttata tttcctgctg ttttgccatt aaaaatcaac
    17701 ataagataca tatctccatc ataatacatt tcctcagaag atacttttat cttaaatttt
    17761 ctcatataca atgcttcttc tattcccttt atataataag aaattcttcc aaatgaattt
    17821 tttaagtctg tatttatcct ttgtgataca tctgtaaaca taccagcgct tgcaacattt
    17881 ataaagtact tattattgac tttccctatg tctattttct tgggttttga atttatgatt
    17941 tcatttatag cttcttttat atcaaatgaa atttgaagag catttgaaaa atcatttgca
    18001 gttcctgtag gcaaaattcc aattggaatt tttatgttta attctttcat tgcatttact
    18061 actaaatcta cagtaccatc accacctgct atcaatatgt gttcataaga actatcaact
    18121 tccttaaatg cattctttac aggttcttta atagtcaatc tatagggtat caataagtaa
    18181 ttttgttctt gatataattc tatgatagtg tctaaatttg ataatatctt tttttcacct
    18241 gaattaggat tgtatataag ttttactttt ttcattattt ctccttactc attttattct
    18301 tttagtatcc aaaatcttca ttcaaaaaaa tcacatgtat tctttctggt gttaattgtc
    18361 tttttataag tgtataacta cagcatattc ttcctggact tgaacagtct atacatatac
    18421 cagtactctt acatccagta tttgtactta atcttttaca attggctgga gcagctattg
    18481 tttttgttct ttttatggct tcatctacat ctttaactat tttatttact cctgctataa
    18541 ctatcacttt atcaggtcca tatatcatgg cagcaactct attaccattc ccatctagat
    18601 tgtaaagttc tccatcctct gttattgcat tagtacttgt aaaataagca tctgcagaaa
    18661 atgactttct gtatatttct ttcatttctt ctggtttgat atcttttgca tatctgtcaa
    18721 gaaaattata tttttctctt ataaaatcaa tcactcctgt ttcaaataag gtcatagaac
    18781 ctccacatcc tactagagaa ccaactttaa ctatttcttc aattttttta agaagctctt
    18841 ctttattact tactaaatac cctttcatat tattattttc taaagatttt attgtttttt
    18901 ctattctttt ttcattaagc caatttaaat tttgatccat tttaacttcc cccttatttt
    18961 taatatgtac ctaattattt ataaacttta ttttctttat aagtttattt tagtaaatct
    19021 aaaaaaaaat acaatataaa acttaaattg ttttccataa ttttttccaa agtaacttac
    19081 tcaatcaaaa aaggaaagta gatgtactat tctactttcc ctatattgta tgtagtatta
    19141 tatattgctt aaaatctata tattaattat atgtttcata ttatagaata tcacagttaa
    19201 tttaaatgta atactatatt cttttcaaac atataaattg tattattaaa tttaatatat
    19261 ccaacttcag taagtcttat taatttgatg aagaagatgc tatagctgca cttgtcgctg
    19321 ccattacaca tgcaatttga atagcaacaa caatatttaa aaatatatta ttagttatag
    19381 agcctatatt attctcattt tgtatgaaat ctgcataaat tgaagctaca atagcagaac
    19441 taatcattac tctattactt tttcctaaag accaatttcc aaagcctttt tcttctttaa
    19501 gtttatttga aacatttttt atctcttcta ttatttcatc ttctctataa tctaatagtg
    19561 aaattgctcc tattattgga tatccataat aattcatttt acaatcattt tctttaaatt
    19621 cttttttgag ttcaatagtc tttttacatt taagcatagt cctatcatca ctaaataaaa
    19681 gaatttggga taatgcttgt aaatcatttc ctttataaaa accattttca tttagaaatt
    19741 cataacattt ttctatgtat tctaaatctt cgtctaaatt ttttgaatga attgcaataa
    19801 gtgctatatt acaatagtca tcactagaag ttagaaatgg atgttttttc ctcatatagt
    19861 tatatattat tttcattttt gatatacatg taagataatc cattttctct ctattttcat
    19921 aaactattga tgctgtaagt ggtaaatatg tatcgcccca aaatttttca cttttaagtt
    19981 ctttgtatat atctaaaatc atcttaaaac tactttctgg atttgattca aatgaaagta
    20041 gtgttgccat ataaaacata ttatatcctc taaaattaga gaataatcca gtattttttt
    20101 taataagctc tattcgttct tctactagtc taggacttat tctcttattc ttaagagtaa
    20161 atgcaagtgc acaactatgt tgtatcaatc ccatttgcca agaaccttta acttcattta
    20221 atgctttgta attttctatt agtaagttta cttttccatt tataaaagac tgttccatat
    20281 tgccctccta gtaatatatc tcattgtatt aatagtttta tatttattat atatatatta
    20341 aatattacaa tcaatacata ttacttcaaa gagcatcatt cttcaacaat aatgtaacct
    20401 tttttgtaat gtcttcccat attattgact ctatcatagt actctgattc actttcatta
    20461 ctccattttg gcacaaatac atctattgca ttagaattgc taaaatactt actagacccc
    20521 ctatccataa cagtttttaa ttttccatct acaataatct tagttccaaa actcaagtga
    20581 ttgtttgcta caaaaccatc ttctaaatca tctcctgtag cagttatcgc tccatatcca
    20641 ttttcttgat tgagacttgt gtaataacta acttcaaaag ttataggtac tagcttcttt
    20701 attttaatac ctaactgatt ttgtaatttc tccttttgta ctttcagctt atactcatca
    20761 ctatttttat agtcttccat accttgatta tacttggaat taaagctttt acctgacttt
    20821 actatagtat cgatatttac tatagattct ttacaatgat ctgcatctat ttttgtttct
    20881 ccatttacca ataatggagt taaacataca ctacatacaa cacatgtaat caatgcttct
    20941 ttaagcttca taaattcccc ccttattatt ttgatatatt agcatattta atattatatg
    21001 tctacattta gatttaaata ccacacccat ttgcttcaag aagttgtctt atatttaatt
    21061 caccttaaac acttataaat cctttatctc agaatcatat agaataaagc tttttctgtt
    21121 aaatatattt tgttaatctt ttaaaaccta aaaccacttt tatttaattt tctatttttt
    21181 agaatttaag aattaaaatt ctataatttt aaaacatatt gaatttattt ttttgagatg
    21241 atataatttt tttaagaggt ggttgatatg ataaaaaata caaaacaaat tacagtagaa
    21301 gttaatgaaa ttttattaca agaaatatct aagataacta atgacgaaaa taatattttg
    21361 acagatttga taaatgaatc aattgtaaat tatattcttg aaaacaaaaa acacaatgtt
    21421 gaagataaag atttagaaga agtgattaaa ttttacaaaa aagaaaatac tgaaaaaact
    21481 aaaagtgcag caagagctat agctgaagca aaaactcata ctttgtatta ataaaaaaaa
    21541 gttcctaaaa attaggaact tttttatttt aataattatt aatatatctc aatatttatc
    21601 aatataaaca tgtttaatac aatctattgt atacttatct taccctagaa ataatcaaaa
    21661 caaaaataaa attatgccct ttatatctaa aacaactaat ttacatgatt aatatacaaa
    21721 aattctgact tttaaattcg tatacaatat caaactaaaa taatattaat gaccccaata
    21781 taaattaaat tctaacaggt ttgattttac atcaaactta ttgtattaat attaaataac
    21841 aagacaaaaa tacttgtaaa aatcacaaat tttacataaa actttatatt tgattcattt
    21901 aactaattat tgtaaaaact atttatttta tgataattaa ctacaccaaa ttattcatct
    21961 tttttaatat ctttaaccca tttttcaaca gagttcaatt cttcttcatt tacccccttt
    22021 ttgaacaaag atttcataaa actctcaata gaacttccat gcatattatc taaaaaagtt
    22081 tttgtttcaa aatgtaaata ctcttcttcg ccaataagaa ctgtataatg tgtatgtcta
    22141 tcaatctttc ttgcacttaa gaattgctta tttactaatc ttgataaaag tgttagtgtt
    22201 gtagtttgct tccaattata tagtttttcc atagcttcaa tgacatcttt tgatgctact
    22261 gtaaaatctg aaatccaaat aaatttcatg acttttaatt ctgctggtgg tatcttagta
    22321 atagtcatat gattttacac tcctctcaaa cttctacata attaaatact atattaatag
    22381 acttttcgag tcaaaggttt tatttaaaat atctcatcca aatttattaa tacaaaaaat
    22441 ttatattttt atttaaaatt aaacatacaa tctattaata taaagataaa tatctattat
    22501 ataagtataa cagattatta aattaaaatt ctaatatttg acataatata tacatttttt
    22561 aaataaatat atacaatgta ttaaaatgta tgcaactcta tttcaaaatc attttgggat
    22621 atatatatgt tataataaat gtataaaatt ttgattggtg ggttatatat gaatgcattt
    22681 attagaaaaa gaaataaaaa ctatgttgtt tacctggaat ttgaagataa agagacaggt
    22741 aaaagaaaac aaaaaaatat gggtattttt gataaaaaaa gggaagcaag caaaagacta
    22801 aatgaggtaa aagaaagctt atataaggac ggttttttag tgccaaacga gattacagtg
    22861 tcagaatttc tattagattt tctaaataaa tatagcgaaa atatatcttt agctacatac
    22921 aacaattacg ttagtatttg taagaattac attaatccat ctattggaaa atataaaata
    22981 caagacttac atcctattca catacaaaac tatatagata aactctctta taaactaaat
    23041 cctcaatcaa ttaagattca tataaatata ttgaaacttg caataaaaag agcctataga
    23101 ctcaaattaa taaaagaaaa tgttatggat ggtatagagg ctccaagata taaaaagttt
    23161 aaaaatgaga tttatgatag ggaacaaatg ataaaattat tagatttagc aaaaaacaca
    23221 gaaatggaat tacctattaa tttggctatt ggattaggtc ttagaatttc agaagtttta
    23281 ggtctaactt gggataatat tgattttgaa gaaaatacaa taacagtaaa taagataacg
    23341 tcccgaatta atggttctgt tattcttaaa gaaccaaaga cagaaagctc tatcaggaaa
    23401 atatcttctc ccaaagaatt aatgtcttta ttaaaagaat ataaaataaa acagaataaa
    23461 aatttattaa aatcttccat tagaaataat aataatttgt tgttttttaa taagaaatgt
    23521 gaacctattg ctgaagatgt tataagtaaa aaatttaaaa gatttttaga aaagaatgaa
    23581 ttacctcata ttagattcca tgatttaaga cactcacatg ttactttact tataaattct
    23641 aaagtaccta taaaggttat atccgagaga gtaggacact caaatataag tactactcta
    23701 agcgtttatt ctcatgtact taaagaaatg gataaagaag cttctgacaa aatttctgaa
    23761 agtttattta atgctaatta atattaaatc aacttagctt agcttattga gatagattca
    23821 ttcatattaa atgtatctat ctcaaattaa taactgctta aataatctgt tttattttaa
    23881 tttatcacct aagttattat acttttttat taaagattgt actttacaat aaaaaagata
    23941 tttccttata gaaaatatct tttaaaatac tattttatta tatacttgct aacattggaa
    24001 tatctaacat cttcttaatt acatcatata ctttttttgc tttatattca ttgtatccaa
    24061 ttaaatatcc tttttcatat gaatcttcag atttagcttc tgtgaaactt aaattataaa
    24121 gccctttaca tccatcttca taacctttat tatactcttt ttctgaaaaa aattttttat
    24181 gatttttttc gttatgtgct gaagatattg ttactccaga atttgatttt gcactagcat
    24241 aaggacaaaa acctttattg tgttgatgtg ctgaatgtcc tccacaataa taataatatg
    24301 ttaactctga tttattttta ttatgatgac tccctgatga attatgccct cctgagtgag
    24361 catatgaaaa atttcctaca ctaatcatag ctaaactcat tactatagct actaaccttt
    24421 tcttaaccat aatctactcc ccctaaaata ttctatattt ttattatagc atctactata
    24481 ttatatttaa atttttagtc tacaaaatat tattctacta ataaacatat ttaaataaca
    24541 taaaaaaacc tcctaatatt tgattaaaaa cttacatact tatgcatagc atgtctcaaa
    24601 tattaaaagg ttttatacta ataattattt atcttttcca tacattttag ctaattgttc
    24661 ttgtatctct ttattttcta aatactcatc aaaatccatt tttctatcca ttattccatt
    24721 tggagttatc tctataattc tatttgctat agtagatata aactcatggt catgagaagt
    24781 gaataaaagt actcctggga acttttcaag tcctttattt acagaagtta tactttctag
    24841 gtctaaatgg ttagtagggt catctaatac aagtacattt gcatttgaaa gcattagctt
    24901 actaagcata catctaacct tttctcctcc agatataact tgagcttctt ttaatgcttc
    24961 ttcaccagag aataacattc tacctaaaaa ccctcttata aagctttcac ttttttcttc
    25021 agagaactgt ctaagccaat caaccaaaga atattctact ccgtcaaaaa acttattatg
    25081 attctttgga agatagtctt gagaagtagt tactccccat ttgtattctc cactgtctgg
    25141 ttcaagttct cccataacta tgttaaaaag tgcagtagta gctatttcat cacccataaa
    25201 tactacttta tcatctctat ccaatctaaa tgacacatta tcaagaacct taaccccatc
    25261 tatagtttta gttaaattgt gtacttctaa aacttcattc ccaatttctc ttgcaggtgt
    25321 aaatcctaca tatggatatc ttcttctaga tggttgtata tcttcaactt ctaatttctc
    25381 taactgtttc tttcttgatg tagcttgctt agcctttgaa gcgttagaac taaatctagc
    25441 tataaattcc tttaattgag ctatcttttc ttcagtcttt ttattttggt ccttagcaag
    25501 ttgtaaagct aattgacttg actcatacca gaaatcatag tttccaacat acatttgtat
    25561 tttaccaaag tctacatcaa ctatattagt acatatttga tttaggaaat gtctatcatg
    25621 tgatactatt ataactatag actcttctaa atccattata aaattattta accagtttat
    25681 tgatttaaaa tccaagtggt ttgtaggttc gtccattaat agtatttcag gcttaccaaa
    25741 aagcgactgt gctaacaata ccttaacctt ttccccacca actaactctt tcatttgttt
    25801 gtaatgcata tctttagtta tgccaagacc cataagtatt ttctcagcat tagtttctgc
    25861 atcccatccg tcaagttctg caaactcacc ttcgagttca gcagctttta taccatcttc
    25921 ttcattaaag tcttccttca tatacaatgc atctttttct ttcattatat tccaaagtct
    25981 ctcatgacct cttataacaa catttaaaac agtttcttct tcatattcaa agtggtcctg
    26041 ttttaaaact gacattcttt ctttatcagt tatagatata ctacctgtat ttggctctat
    26101 ttctcctgat aatattttta aaaaagtaga ttttcccgca ccattagctc ctattattcc
    26161 atagcaatta cctttagtga attttaagtt gacatcttta aatagttcct tatcaccaaa
    26221 tctaagtcca acacctgtaa cttgtaacat taatatattt tcctttcttt ttactcataa
    26281 tttattttat cataaaactt tgataacatt tttattatct attatcacgt aaatagtata
    26341 ttttttatac caaatttgtg aaatatttat taaaacaata ctaaaaattg taaatttatg
    26401 aaaattaaca atctcttata ttatacttat aaagaaatca aattgcaact ttattcattc
    26461 ttttacacat tgaaaatcag ttattataac ttttaaataa atatgctttt cttaaaacat
    26521 cattctagtt gttttgtttc atatttaaaa agagtactta atttgtaaat actctttttt
    26581 aatagcttta tattttagca aaattacatg caggataagt acacacatca cagttcatac
    26641 aaagaccacc atggccatat ctagctatat catacttatc aagtttttca tcaattaaaa
    26701 ctctagataa aactatatca aatactgtag ttttgtgata cattgcacat cctggtatac
    26761 ccataattgg aacttcgcca taataagcaa gtaaaaacat agctcctggt aatattggtg
    26821 aaccatatgt cactaaatca gctccagttt cttttatagc tgttggtgta acatcatctg
    26881 ggtctacact catcccacca gtacagcata taagttctgc tccttgactt ataaattctt
    26941 ttattgcatt ctttataacg tctttatcat ctgggcatat agtctgtcct ataacttcac
    27001 aaccaaaacc ctttactttt tcttctatta ctggtccaaa tttatcaaca attctgctat
    27061 aaaatacttc atttcctgta gtaacaattc ctactttctt aggtttaaaa ggcactacat
    27121 ttactatttt tctattacca actacttttt ttgcatcttc taattttttc tcatctataa
    27181 ccaaaggtat cactcttgtt ccagccactt ttaaaccttt atttactata aaattattat
    27241 gaagagtagc catcattatt tctccaacac aattcaaatc aaaaagtgca tcaacatcta
    27301 tctttaaaag accatcacat gctgctataa aatctatttt tccttctttt atttcactaa
    27361 aatctaaatt ttctccagca gttagttctt ttaaaaacaa tgcaccttca ttttcatgaa
    27421 ccattccttc tgacttttcc catacataca aattatcttt accaagagat aataacactg
    27481 gaatatcttc ttcttttact atatgaccct ttttaaattt tcttccttta aattcgccag
    27541 gtattatttg agttatgtcg tgacataaaa cttgtccaac agcatctata gtttttatta
    27601 gtttcataat ttacccccaa ttctttcata gtctattttt gtatcgatat caaataacat
    27661 ttctttagga acttctacat actttatttt tgatgaattt tttaaaatag ttttaccctt
    27721 ttcatcttct ttaagtgcta acaattcttc tttcttacca tatgggaata taactggatt
    27781 tccacatata tctttgtatc ttggaattac tataaaatct ctatctaatt taaaagtatt
    27841 tataatttta tctatatata agttatcaat aaatggctgg tctcctacaa agaacatata
    27901 accatcacat tttgagctat ttaaaactcc caattttata gattcacttt gacctacatt
    27961 tgcattttta ttatctatat attcaaaacc atatttatta cacaataata aaacttcttc
    28021 atattgactt actactacaa cttgatgaaa atcaatctta ttgactactc taaatacatg
    28081 ttctattata gaacatcctt tataatctaa taaaagttta tttactccca ttcttctggc
    28141 aaaaccggat gccattatca ctgcatttat catatatatc atccttggta tttatagtat
    28201 atttataata tattgatagt tctatgattt ttataatatc tctattgata ttatctatat
    28261 atataatatc atataaacta ttttaatact tcaatatctt gcacaaaatt tttgttttac
    28321 acttccataa aatatctcta tttcactttc acattcttta atatttttta ttaattttat
    28381 agctaaattt ttatattttt cattttcaac tttattaata aataatactc tttttccaga
    28441 ataattttta aataatccat ttggatttaa tactatattt tttaagtttt caatacttac
    28501 tgtagagcta ctattaatac tctttgtatt taaatttgct atttttttga acatttctac
    28561 tctgtgtata ttttcttcat taatatccat tccaaatgat gttatatcta atatacctat
    28621 agtttttgta gttttatgat atactactgg ttctttagta ttccaacctt taagtttttt
    28681 tctctttgaa ccatctcctt ctattaaaac taaatcaaat ttgtctacaa tttcatccaa
    28741 aatagatgaa tcaatactta ctaatttatt ttcattattt atatgactac cacatactat
    28801 tattccatga caaatagatg gaataatagt tccatctatt gtagtaatta tattgtcata
    28861 atcatttggt acatatattt tagttgttgt tgtaagtaga actttcaatt tatctctata
    28921 aaaatttgca aaatagttta taaatgaagt ttttcctcct gctccaacta cagttattat
    28981 ttcattcttt tctattatat ttgatagttt cacactttca cctcttataa ccagttttct
    29041 aatctattaa tttttacagc tagacctttt tagtaaaagt gatttttgaa attccataaa
    29101 ctcgaaagta aatagattct gttgtaaaca acaaggcgga tccaattcgc cgctaagctg
    29161 taagcttacg ctatcagttt atcttttaaa tataattatg atattcttac tctctgtggt
    29221 tgctttaata tttgaggatt attctgcaaa ttagataaat taactacttg tgattttttt
    29281 aatatattaa gactcgcatt tacatctgca tttataatga ttccaacact ggatttatac
    29341 tgtccacgtg ttattctttc ccctttaaag tcatattttt tcacattgtc cacattgata
    29401 tcaggtagaa aatcattggc aaaaaaatca gatttactag tatagctttc ttcttgccta
    29461 ataaaattga tattttttat tttacataga tattctaatt ttccttttat ctctccaaaa
    29521 gggattctta taaaatttct atatattttt ctctccatat tatcactttt ttctaactta
    29581 gcattatatc ctacaattaa attaccaata ttatttttta tacagtaatc aattatgtaa
    29641 aaacaagttt tatttacata gtctttgact tgattatttc tcttattcca aactttaaat
    29701 tgttttcttg ttattgcagt tatattcttt tttaatttta aggcctctat tttatcattc
    29761 tgtttgtttg cccactgatt cacagattta agccttttgc catctatgat aaaactatca
    29821 cctaaattgg taacacatgt acataaattt tctaaaccta aatctatagc tagtgcattt
    29881 ttttgatttg aaacttcctc tgatttcggt atttcataac aatactgaat ttcaaagaac
    29941 ctagctttat gtttaggtat tattcttatt tctttaattt ttttctctag tatattttga
    30001 ggaactttta tacttacttt tccatatagt tttttaaata ctggagacat aggtacattt
    30061 agagtcccat cttctttgat tcttatttga cctattatta tactaaaaaa tccttcttta
    30121 tctaaatatt taggtgactt tatccctcta aaatcatatt taccttcttt ggctaattta
    30181 attaatccaa aaaacgacct aaatgaactg tcgacttctt ttaatatttg ttgcgctata
    30241 ttactattga gaagcttata attctcattt tctttacata catggtaatt agcttcatag
    30301 ttaagatgtt ctccttgatt aaaataatgt tgtctcacat tatatgtacc aacattatat
    30361 aagttcttgg ctaagaagca catctctcgt agagcttgat attctttttt agttaagttt
    30421 tttaattgtt gtctctgggt tccatagtgt atatttttta ttctgtttga cattaactca
    30481 cctcctttag aatatactct actagacatt atatacggta tttttataaa acaccatata
    30541 taatgtccat ttaattactt tattttacaa aataatttaa atttacaagt ttttatacaa
    30601 catattactt attataattg tttattatta tttttcatac ccatataaac tttttcaaaa
    30661 gtcataggaa gctctcttat acgaactcct gtagcattaa atattgcatt tgctatagct
    30721 ggtgctggtg tatgtataac tatttctcct aatgatttag caccgtaagg acctcctgag
    30781 tcgaaattct cagcaaaatc taccaatata tttccaactt ctttttttgt aggaacttta
    30841 tactgtagga aactatttgt taataatctc ccatctttat caaatctagg gtcttcatac
    30901 attgcaaacc ctatacccat catcacaccg ccttctactt gtattctagc caaagttgga
    30961 tttataactg ttccacaatc aggtacacat gcaaaattta ttaccttata ttcgcctgta
    31021 tttttatcta attctatctc tgcaaatcct gctataaatg gttttatttt ttttaatata
    31081 ccaaaagatt ctgttgcttc caaaactact ggtacatcat cactagcaaa cccaattcct
    31141 ccaacagatt ctctacccaa ttcctccaat aaaacaaact tactattatc gtttttaaca
    31201 aaaaccctgt cttttcccaa ctctaaatct tcttttttaa atcctagctt tgactccgca
    31261 actgaaagta atatatcttt taatttattt gctgtcttta ttgttgcatt tcctgtaacc
    31321 gttgtcgtac aagaagcgaa tgctcctgta tcatatggac ataaatctga atcacctgta
    31381 taaatagaaa ttctatctac agtagtattt aaagcttcag cagcaatttg tgcttgaatt
    31441 gtatcagctc cttgacctaa gtcagcaaga ccagataata atttgtatgt gccatcttca
    31501 tccattctta tagtcactgt tgccatatct acacgtggta taccagaacc atgatttgct
    31561 actgccatac ctactgctct tactttgtta tttcctatat ctttacatgg atatttatca
    31621 tcccaattaa ttaatttctt ccccttttct atacattgtt tcaactcaca acttaatatt
    31681 tcaccttcag ctgcttttcc actagtatac ctatctatta tatttttaat tctaaattca
    31741 agtgggtcca ttccaatctt atgtgccaat tcgtcaatag cactatctaa tgcaaatatt
    31801 ccctgtgtag caccatatcc tctaagtgct cctgctggta acctattagt atatactgtt
    31861 ctagcattga atctaacagc atcaatatca ttatatattg gtaaggtatt gtgtccagat
    31921 tcagaagaaa cagagacacc attcccacca taagcacctg tattgtttaa tgattttaat
    31981 tctattgcct ttaaatttcc ttctttatct gcaccgactt taacatcaaa aaacatttca
    32041 tgtctactat tagaacctac aaaagtttca cttcttgtaa atacaaattt tgctggtcta
    32101 ccagttttca tggtaacaaa cgcagtaaat atatctgtag ctgctatatt ctttcctcca
    32161 aatccaccac ctattctagg tttaattact cttatttttg aagatggtat acccaatact
    32221 tttctaagga ttctctttac attgtgtggt gattgtaatg atgaaactac aacaattcta
    32281 tcatttatat ctttatatga atatgaccta tgagtttcca tcatacaatg tgattgactt
    32341 tgagttttat atgaagattc aaccacaaga tcactttctt taagcttagc ctcaacatct
    32401 ccaaattcaa aaaattcttt tgatactata ttattgtttg catccaatcc aaaagggtat
    32461 ggctctacta tgtctttttc tggatgtata acaacttcat ttccttctgc ttctcttgca
    32521 tcaaacacag gttttaaaac ctcatagtct acctttatca tttttaaggc tttgagtgct
    32581 attttctcat cttcagcggc cactaaagct acttcatctc caacaaatct aactctatct
    32641 tcaagtaaaa ctctatcata aggtgatgct tctggctctg tttggcctgg aacacagtat
    32701 ctgacctgtg gtacatcttt atacgtataa atacccacaa ctcctggaat tttttcagct
    32761 tttgatgtat ctatattctt tatcttagca tgggcatgtg gacttctaag taactttaat
    32821 gttaaaacat ctttatgcat aatgaggtct tcagtatata gaggttttcc tgtgacaatt
    32881 gctgtactat ctatctttct tatcccctta ttaatcatta tacattccct cctcaatagc
    32941 attatacatc cttttaacta atgcacttgc catatccttt ctgtactctt tgctagctct
    33001 catattactt ccataagtaa gttccttact agcaacaata gatgccttat ctatatcttt
    33061 ttctttattt aatatattac ttgcttcaag tgctaatcta gctttttgag gtcttgcccc
    33121 aattgctatt ttgtaagtat tattttcttt taacattgct gaatttaata tagaaaaatc
    33181 tcctgtgcac tttcttattg agtcaaaaac agctatcgca tcttttttcg gtagtattac
    33241 ttcgaccaat atatccctac ttaattcact atccaaaaac tcattcaact ccagcattcc
    33301 tttattgtat aatcttacct ttgccccgac aaccaaaagt gctggtatta aatcagaaaa
    33361 accatacttt gaaaatacac ttgcaccaat tctagctcct tgtctaaatt gaacaccaac
    33421 tatgttagaa acagcacttg aaagtattcc actacaataa ttttttatag ttttatccat
    33481 ttctaaactt ctaagagaag tatctgcacc tatcaaaata tttttttcat cctcttttat
    33541 ataatttaga tttatatctt ttaaatctat cgctgttcct atatttttat tgcttaattt
    33601 tatgaatcca catccaccta aaataacatt atttttttta gaagttaaaa ttttatatgc
    33661 ttcttctaaa ctctgtggaa ctgaatattc ctttatagta accatcttat ccccccatca
    33721 ttagcttatt aaaacataag agttttaata aatcttttta tttatattta taattgtagt
    33781 atatttaatt cacatgtata aaatctttac attataaact tttattttta tcctcaactt
    33841 taccattttt atttttagga aattttacca tatataaagc ttggattatt atggctacca
    33901 tagctcctga aactacactt gaatctgcaa gtaatgtttc tacaaacttt ggaaatcttt
    33961 caagaacttg aggagctacc atgaacccaa taccagaagc catagaaaga cctaatatca
    34021 tgctattttc ttgattaaat ccatccatac taacaagtcg taaaccagat gttgtaagag
    34081 ttgaaaatat aacaagtgtt gcccctccaa ccacacaagg aggaattgtt cttattaaat
    34141 tagctaataa aggcgatatt cccgccaaaa atagtccaat tcctccaata gctagtacga
    34201 atttacttac aatctttgta ttggaaacga ttgcagaatt ttgtccaaac atccccattg
    34261 gagttgcaga aaataatgca cctattgtag agagtactcc atttcctaaa acagcagaag
    34321 aaagttcttc atctgttact tgtctattaa gccctcctac cgcagaaagt gtgcaggcac
    34381 ccattatatc agctatctca actaaatata ttattgaaaa cattacaaca acttcaagtc
    34441 ttatatctag accaaaaata agcggttttg gaagtgcaac caaagtaaac tcttgaattg
    34501 aagaaaaatt tactattcct aaaattaatg ataaaatgta tccaaagatt atgctaacta
    34561 atattgatgc atctttaaat aatccttttc catacttgtt taatcctaat atcataagag
    34621 atacagatat tccaactata aaattaattt gattcccaaa agtttcattt cccatacctc
    34681 cagctaagtt ttttatagct attggaaaaa gcccaagacc catacatgca actattgttc
    34741 cagatacagc tggagtaaat ataaatcgta tttttttaag accaaaacca attataatta
    34801 ttactatacc agctattatt tgagaaccaa ataaaactgg tagtccatac ttacctgcaa
    34861 cagatacccc agctcctata aacatagctg tagctcccat tataactggt attcctcctc
    34921 ctaatttaaa acctttaaac aaaggtattg gatataattg taataaagtt gataatcctg
    34981 caaaaattaa tgcggcttga atcaataatg ttgacatctt atgattaagt ccagctgcat
    35041 ttgcaatcaa tatcgctggt aaacaactac ctattaccat tgccattaag tgttgtaacc
    35101 ctaaaggtat tgcttccttt agtggtggca ttccgtctaa ttcaaatttt gatgtacttt
    35161 ttgctttcat aataaaaact cccgttacat aaaacttatt gaattatata aatacttaaa
    35221 aatctaatat attaaattaa tgatgttcat aaatcgcaac tatactccaa cacatattta
    35281 agtttttggt ctaaaaaagg atacaataaa tttaattatt aacaaataaa cttattcttt
    35341 aattttgcat atattatata taatgcttta caaatataag agtattatag ctatgaattt
    35401 ttaatttttt atagtaaatt taattcaatt taaatctttc aatcttaatc attataagtt
    35461 ataagttttc ataagtattt atatttttca agttttaaac atttacctat aaacgctact
    35521 ttatagatgt cacttcaaat ccagtgacct catactttca tatgagcgta gactatttct
    35581 tcatcttcag cattacctgc taagagcaac ccgtttccac tatcaatcac ttatagtgta
    35641 ctctctctcg agatagtcgt ttgaccttcc tatttctagg cttggcgacc aaatgtccat
    35701 ttttaagtac ttaggctctc accatatacc atcctcacta ttatttctgg ttttcaccac
    35761 attcataaaa gtttctttct atcttttatt gtagttgtaa ggctttagga tttactggtt
    35821 ttaaagttgt gtcctacata gatttctcta tgtacggggc taaaagtaca atttatttaa
    35881 tatactttgc tttaccccct gtaaataata ctatttactc tttcactgtt tttgttatta
    35941 aattaattaa atagcaatta atctaagcat aaaataattt tttaatttaa actcaaaata
    36001 tttatgaata ttttataata taattctcat aagacagaaa aacttaataa gctatgtatc
    36061 tcagttgtac caatgtactc tc
//
LOCUS       DBGJFK010000035        35986 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.035, whole genome shotgun sequence.
ACCESSION   DBGJFK010000035 DBGJFK010000000
VERSION     DBGJFK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.035"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            123..959
                     /locus_tag="ACOIAP_002016"
     CDS             123..959
                     /locus_tag="ACOIAP_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HGZ2638899.1"
                     /translation="MKKEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPEFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLH
                     SNLENTNIEVQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPINAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            980..1402
                     /locus_tag="ACOIAP_002017"
     CDS             980..1402
                     /locus_tag="ACOIAP_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HGZ2638900.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFEDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(1612..2775)
                     /locus_tag="ACOIAP_002018"
     CDS             complement(1612..2775)
                     /locus_tag="ACOIAP_002018"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGZ2638901.1"
                     /translation="MKKLASTALAILLAFTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGDIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELVNTKDINKASYLQMLQRIIDNMI"
     gene            complement(2829..3029)
                     /locus_tag="ACOIAP_002019"
     CDS             complement(2829..3029)
                     /locus_tag="ACOIAP_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1290 family small acid-soluble spore protein"
                     /protein_id="HGZ2638902.1"
                     /translation="MDNVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(3235..4911)
                     /locus_tag="ACOIAP_002020"
     CDS             complement(3235..4911)
                     /locus_tag="ACOIAP_002020"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGZ2638903.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGIGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDIYKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            5128..5865
                     /locus_tag="ACOIAP_002021"
     CDS             5128..5865
                     /locus_tag="ACOIAP_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HGZ2638904.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTLGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKI"
     gene            complement(5982..6440)
                     /locus_tag="ACOIAP_002022"
     CDS             complement(5982..6440)
                     /locus_tag="ACOIAP_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGZ2638905.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(6722..7009)
                     /locus_tag="ACOIAP_002023"
     CDS             complement(6722..7009)
                     /locus_tag="ACOIAP_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGZ2638906.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(7087..7512)
                     /gene="ruvX"
                     /locus_tag="ACOIAP_002024"
     CDS             complement(7087..7512)
                     /gene="ruvX"
                     /locus_tag="ACOIAP_002024"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGZ2638907.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKEETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(7664..9835)
                     /locus_tag="ACOIAP_002025"
     CDS             complement(7664..9835)
                     /locus_tag="ACOIAP_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638908.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGKKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYGTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILSTFGLE
                     NKEMVGRSYTLVNKEDNVNYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKGNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLYVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAILLAVSAVVVVFAFAALDIVSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(9845..10102)
                     /locus_tag="ACOIAP_002026"
     CDS             complement(9845..10102)
                     /locus_tag="ACOIAP_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGZ2638909.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(10127..12766)
                     /gene="alaS"
                     /locus_tag="ACOIAP_002027"
     CDS             complement(10127..12766)
                     /gene="alaS"
                     /locus_tag="ACOIAP_002027"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGZ2638910.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVKLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAKEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGSISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(12834..13072)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(13215..14294)
                     /gene="mnmA"
                     /locus_tag="ACOIAP_002028"
     CDS             complement(13215..14294)
                     /gene="mnmA"
                     /locus_tag="ACOIAP_002028"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGZ2638911.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDDVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNEN
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGKDTIKIVFDEAQRA
                     ITKGQSVVMYDEDIVVGGGIIEKSL"
     gene            complement(14578..15018)
                     /gene="nifU"
                     /locus_tag="ACOIAP_002029"
     CDS             complement(14578..15018)
                     /gene="nifU"
                     /locus_tag="ACOIAP_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HGZ2638912.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAKKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(15072..16265)
                     /gene="nifS"
                     /locus_tag="ACOIAP_002030"
     CDS             complement(15072..16265)
                     /gene="nifS"
                     /locus_tag="ACOIAP_002030"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HGZ2638913.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(16283..16729)
                     /locus_tag="ACOIAP_002031"
     CDS             complement(16283..16729)
                     /locus_tag="ACOIAP_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGZ2638914.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(16838..17608)
                     /locus_tag="ACOIAP_002032"
     CDS             complement(16838..17608)
                     /locus_tag="ACOIAP_002032"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2638915.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADIDELGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRARGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(17639..18904)
                     /locus_tag="ACOIAP_002033"
     CDS             complement(17639..18904)
                     /locus_tag="ACOIAP_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGZ2638916.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKNFYKINATNSSLEDIKNVISELGSINNISGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKIDIEKGL
                     KRAVEVLNKDSYMDIECNKDAIEYIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDIIKASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSVYYIPQENKTEKNIKKYLEYLDGDF"
     gene            complement(19020..19805)
                     /gene="codY"
                     /locus_tag="ACOIAP_002034"
     CDS             complement(19020..19805)
                     /gene="codY"
                     /locus_tag="ACOIAP_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGZ2638917.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDAQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(19970..22057)
                     /gene="topA"
                     /locus_tag="ACOIAP_002035"
     CDS             complement(19970..22057)
                     /gene="topA"
                     /locus_tag="ACOIAP_002035"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGZ2638918.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELANEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDAKKVQDAHEAIRPTSVDRTPDSIKASLSKDQYKLYNLIWRRFVASQMEDSIF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(22090..23190)
                     /gene="dprA"
                     /locus_tag="ACOIAP_002036"
     CDS             complement(22090..23190)
                     /gene="dprA"
                     /locus_tag="ACOIAP_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGZ2638919.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICQYDKEYPENLKNIYNAPKLLF
                     YKGDIDLVNNKFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(23209..24810)
                     /locus_tag="ACOIAP_002037"
     CDS             complement(23209..24810)
                     /locus_tag="ACOIAP_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HGZ2638920.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDISNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQKIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLNDKSKKENEELEKDNSYIDFKYTKINDEESKYNEDF
                     EDIKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISIEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLIAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFR"
     gene            complement(24841..25185)
                     /locus_tag="ACOIAP_002038"
     CDS             complement(24841..25185)
                     /locus_tag="ACOIAP_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HGZ2638921.1"
                     /translation="MNNKEKGDFGEEIAVNYLLSKGARILEKNYRLKIGEIDIIAKMG
                     REVIFVEVKSRSNIKFGYPCESVSYKKRKKIIGIANYYIIKNNLNNTPVRFDVIEVYL
                     LEKRINHIVNAF"
     gene            25369..26532
                     /locus_tag="ACOIAP_002039"
     CDS             25369..26532
                     /locus_tag="ACOIAP_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2638922.1"
                     /translation="MNRKKLVAFIRYLSLFILVVSYLKNVENTLYPVIIMMILFIIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFTLVIISSLIISLDKNIYLALESSSVLLIITILSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLISELVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIGLYRLIQESLSNSSRHGKATEIKIFMTFNPSNFIITISD
                     NGIGCGNIKKGNGLNSISERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            26525..27172
                     /locus_tag="ACOIAP_002040"
     CDS             26525..27172
                     /locus_tag="ACOIAP_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGZ2638923.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKTNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTPEKMIEQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISKELFLSEGTIKNNITNILGKLELRDRTQLAIFAFKNKIVIE"
     gene            27301..28236
                     /locus_tag="ACOIAP_002041"
     CDS             27301..28236
                     /locus_tag="ACOIAP_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638924.1"
                     /translation="MDIVRVNNITKRFNDKLALDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGNLLKERINEALEVTGLTEVKKKKVKKLSDGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDMSKKYETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NAYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISILENNSLLELDIDKKLQLTEI
                     LSVIDKNNSKIIRISYEEPNLEDVFLNLTGKNLRD"
     gene            28250..29350
                     /locus_tag="ACOIAP_002042"
     CDS             28250..29350
                     /locus_tag="ACOIAP_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638925.1"
                     /translation="MKLYMSVKTMLKGLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNHLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIIGNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRIIGITFKGNFAILLLLCALSSYFMTSISTFVNS
                     FFSKKYGTIIVYALLFLQTIFGGIFSMISDAFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLITSTILIALAIVKEKYKWREVQ"
     gene            29350..30414
                     /locus_tag="ACOIAP_002043"
     CDS             29350..30414
                     /locus_tag="ACOIAP_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638926.1"
                     /translation="MIRLTVANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDNLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKMDKNIDDKLTKTNIIDN
                     KLDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFTLLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWIARVFKNESSIS
                     LISTFYSLIGLAISLSSLIPSMDKLSFMANLSKLTPFYWTIDAIKNNGSILINIIILI
                     LIGTIFVTAGSLKLRDFAKN"
     gene            30658..31155
                     /locus_tag="ACOIAP_002044"
     CDS             30658..31155
                     /locus_tag="ACOIAP_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HGZ2638927.1"
                     /translation="MYKIGESVMYPKEGACCVNDIVTKKINHQMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDKFIQSIDKTDGVWVFDRKQRLKLYHDKFHSGDVF
                     EIVKLIKMLMIQDCSKQLCSTDKEFLNKAQRFALSELAAAQCKSYTVVLEEMKKHILN
                     SKSKN"
     gene            complement(31328..31576)
                     /locus_tag="ACOIAP_002045"
     CDS             complement(31328..31576)
                     /locus_tag="ACOIAP_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638928.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(31643..32659)
                     /locus_tag="ACOIAP_002046"
     CDS             complement(31643..32659)
                     /locus_tag="ACOIAP_002046"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HGZ2638929.1"
                     /translation="MEYNELLKNARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVEQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(32717..33484)
                     /locus_tag="ACOIAP_002047"
     CDS             complement(32717..33484)
                     /locus_tag="ACOIAP_002047"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGZ2638930.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYNKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDIAQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(33552..35741)
                     /locus_tag="ACOIAP_002048"
     CDS             complement(33552..35741)
                     /locus_tag="ACOIAP_002048"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HGZ2638931.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRDLAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEEFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNLMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKENKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        11529 a         6228 c         3917 g        14312 t
ORIGIN      
        1 actactgtaa gtgtaatatt atattgacat gaattgacat tattatgttt tagtcaatat
       61 catacaagaa gtataaaaaa atatgtgtta cactttttat aacatgaaag gaggttaact
      121 aagtgaaaaa agaagaacgc acagtatgct ttgataggga attaaaaatt gaagcatata
      181 gatttaaagg cataatgcaa aaattcccaa accattttca tgaacattat gtaattggtt
      241 ttatagaaaa aggtcaaaga tatttatctt gtaaaaataa agagtatacc acaagtactg
      301 gagatttgct actttttaac ccttttgata gtcatacttg tgaacaaata gatgataaag
      361 tacttgatta cagatgtatc aatattaagc cagaaataat gaaaaaaact gtctttgaaa
      421 ttacagggaa aaattattta ccagaattta atcaacctgt tatatttcgc agtgagctag
      481 tacctctact acaagaatta cactatataa tcatggagga agaattggac tttaaaaagg
      541 aagagctttt tttctttcta attgaacaat taatcgaaga acatacagag ccaaatttgc
      601 attctaactt ggaaaataca aatatagaag ttcaagcagt atgtgattat ttagaaaata
      661 attatgctga acatatagta cttgatgaat taagcactat agcaggtatg aataagtact
      721 ctctacttcg taattttaca aaattaaaag gtattacacc atatagatac ctagaaaata
      781 tacgagtaaa caaagctaaa aagcttttag aaaaaggtgt agagcctata aatgctgcga
      841 tacaaacagg atttgtagac caaagtcact ttacaaactt ttttaagaat tttattggtc
      901 ttacaccaaa gcagtatcaa aatatattta taaatgacga ttcaaataac tttaaataag
      961 gtaaaaagga gaaataaaaa tggaaactaa aaattcaaaa tgtgtcatgg taatagatga
     1021 aaatttacca atgggaatta tatctaatac agcagctata atgggaatta cattaggaaa
     1081 acatgctcca gaaactgttg gaccagatgt aattgacaaa acaggtaata gtcacttagg
     1141 aattattgac attcctgtac ctattttaaa aggaaacaaa gaaataataa aagatttacg
     1201 taaaaaatta tatactttgg aatttgaaga tttaactgtt gtagattttt cagatgtagc
     1261 acaaagttgt aatctttatg aagaatttac acaaaagatt gctagtgttc cagaagatga
     1321 gttacagtat tttggtatag caatttatgg aaataaaaag aaagtaaata aacttactgg
     1381 tagtatgcct ttacttcgat aagtgttaat cattcatgta tatgatatta aatcaaatga
     1441 tattgtatga tacataaact tttctatatt tatataaagt cataagatta taaaatactt
     1501 atatacagta aataaaaata cccctatgga aaataattac ataagggtat tttttatgtg
     1561 tattataatt acatctttgt atattataat tatatttcac ttgataatta tttatatcat
     1621 gttatcaatt attctttgaa gcatttgtag atagcttgcc ttatttatat ccttagtatt
     1681 taccaattcc acttcgccta ttactttttt atctttacat atctttatct ttcctaaaac
     1741 agttcccttt ttaattggca tcttaggatt ttttactatt tcaattttct tctcaaattc
     1801 tttagagctt ccttttttaa taagagcatt taaatcttct ttagcaacca atttaacttt
     1861 gttttcatca gccttatcca atgtaagtgt tgctatatta tcgcctttac tacataactt
     1921 aacactttca taattagcaa atccatagtt taaaagacta gatgcatcat taaatctttc
     1981 tggagatgtc tctgctccta aagttgcagc aactagatga gtattacctc tctttgcaga
     2041 tgctgataaa cagtattttg cttcttgagt aaaaccagtt ttaacaccag tagctccttg
     2101 gtagtgtttt ataagtttat tggtatttgc aagacctact gtaacttgtt tcttccctac
     2161 tacaacctta tccatccatg tagttaagta tttacttatc atttcatgtt ttaacaattc
     2221 tctagacatt agtgctatat catgagcaga tgtatagtga ttagcaactg gaagtccatt
     2281 tgtatttgca aaatgagtat cattcatatt taactctttt gccttagcat tcattctatc
     2341 aacaaaccct tcaacacttc cagctaagtg ttcagccata gcaacacaag catcatttgc
     2401 tgaagcaaca gctataccct ttaataacgt atcaaccttt tgagtttctc ctggttctag
     2461 aaatatctga ctaccaccca tactagacgc agtttcactt acttgaactt catcatcaag
     2521 cttaatatca cctgaatcta aagcttctac aataagtaac attgtcatta cctttgtaac
     2581 actggcagga ggaagctttt tatgtgcatc cttttcatat aaaatttgtc cactaccaac
     2641 atccatcaaa attgctgatt ttgaagatat atttagttga ttggcatcag cattttcctt
     2701 attatttgca aaagaaaaac tcaaaggagt aaatgcaagt aatatagcca aagcagtact
     2761 agctaatttt ttcatcgatg tcacctctta aagtttattt aaacttattt tctcacattt
     2821 aacttttttt attctaaatg cctagatata ccttgaccta aatttttttt cttttcaagc
     2881 tttttaaagt aaccttctaa aacaccttta ttagatgcat tttctattat ttcaaaagca
     2941 tcttcataat tcattccata ctctcctgct atttccattt ttgtttgttt taaagctttt
     3001 atagcatttt gtcttgaaac attatccata agaatcctcc tatcagtaaa atttatatat
     3061 aagtagtttt tactaataaa agattgttat aattggtatt ttatgtaata tacatatttt
     3121 ctaaatcaaa aactaaaaag acctcttgta attcttaaga taatatcaat tggatttttg
     3181 atattacttt aaaaattaca agaggtctaa ttttcaaatt tatagttttt tatattatac
     3241 ttccattatt ataggaagta tcattggatt tcgtttagtt ttttgatata aatattcttt
     3301 taggttttct ttaatattat tctttaaata agcccattct ttaatatttt tctcttcaca
     3361 ttcatttaga acattcttaa ttatatcctt cgcaccatcc atcaaatctt ctgactctct
     3421 tacatataca aatcctctag aaattatatc tggacctgct aaaactttac cctcatcctt
     3481 agaaatagta actacaacta tcataagacc atcttctgat aaatgctttc tatctcttaa
     3541 aactatatta cctacatcgc ctactcctag accatcaact aatatatttc ctgtttgtat
     3601 acggtttgct accttagcag aatttttatc taattctaaa acatctcctg tttgcatgac
     3661 aaaaatattt tctttgtcca taccaagctg ttcagctatt tcagcatgtc tttttaacat
     3721 tctatattca ccatgagctg gcataaaaaa ctttggtcta actaatgcat gtataagttt
     3781 taattcttct tgacaggcat gtccagaaac gtgtatatca gctatatcac tgtatactac
     3841 ttctgctcct ttttcaaata agaaattgat tactcttgat attaattttt catttcctgg
     3901 tattggatga gcagatatta taactaaatc gccactcttt atttctactt ttttgtgctc
     3961 tgaaaaagcc attctagcaa gagctgacat aggttcccct tgtgaaccag ttgttattat
     4021 cactaattca ctatcttcat acttatatat atcatttaaa tctataagca tgtcatcaga
     4081 aatatctaga tatcctaatt cttttgcaac tccaactaca ttgaccattg agcgacctga
     4141 tatagcaact tttctattaa acttctcagc agtatttatt atttgttgta atctgtgtat
     4201 gttggatgca aaagtagcaa ctataattct tctgccattt ccttttgcaa ataattcgtc
     4261 aagacctatc ccaacagtct tttcagacat agtaaatcct ggtttttctg cattagtact
     4321 atcagccagc attaaaagaa ctcctttttt gctcaactca cagattctat gcatatccat
     4381 aacatctcca tcaataggag tcaagtcaat cttaaaatct cctgtatggt atattatacc
     4441 ttggtctgtg tgtattgcaa tagagtaagc atctggtata ctatggttat ttttcaaaaa
     4501 ctctacttcc atattatcaa gctttataac ttgtctagga cctataacat ttaacttaac
     4561 attattcatc ttatgttctt taagttttac ttgtataaga cctatactaa gtcttgctcc
     4621 atacacaggt acatttattt tctttaatat atatggaaga gctcctatat ggtcttcatg
     4681 tccatgtgta ataaatatac cctttatttt atccctattt tttactaaat aagttatatc
     4741 tggtataact atatctactc ctaacatttc atcctctgga aaactaagtc cagcatctat
     4801 aacaattatt tcatctttat actcaacaac agtcatattt ttcccaactt cgttaagtcc
     4861 acccaaggcc attaccttta tcttgttggt gttctttttg aacaattgca tcatctcctt
     4921 ctgtctattt aattttttaa cacgttctac aatcataaat aatatcaaat cacgcactcg
     4981 ctaccagtta ttcttattgt accataattc gtatcatatt ttaagctata tttaaaatac
     5041 atttaacgta ttattttgac aaacctattt tattttgata tcctctaaat attatatgat
     5101 ttaatatcgg ataatttagg aggatttatg cgtggtaaaa ctcattgtgc aataggaatc
     5161 ttaacagcta tccagacatc tttaatattt aaaattccta tatctttagt tgatatttta
     5221 gtttcagcta cttttgctgt actgcccgat ttggataaat ctaattctat ggtctcaaat
     5281 ttcattctaa agaacaatgt atccaaatac atatatagaa tttttatata tgctgttaat
     5341 attattattt tctttatttc aataaatata aatgataatt tttatttaag cgcaataatt
     5401 acatttgttg caattataat tattgaagca aaactaaccc acacatttct aagaaaagtt
     5461 tttctatcat taatatttat actattagct atatgcttat acatcataga agttgaaata
     5521 tattttacaa ttttttgtct aatgttgtca atttttccat ggttaaagca cagaagtttt
     5581 tctcatagca tatttgcaac tataatagta tattttttac taaaacagat agaattaatc
     5641 actaatatta ataatttatc tttttatggt acgcttggtt atgcaagtca tatgttttta
     5701 ggagatttat ttacaaagca aggaatacca attttttatc cactaagcga aaagaaaatt
     5761 tctttaggat ttttaactgt tggaggacca tttagtaatt tcatagaaaa atcattcatt
     5821 tttgtactta taggattaat tatattttca atattaaaaa tataattagt ttaaaaacta
     5881 tatatttaca ctttatagat tgcttataat aaaaaatgga agaatagcat agaatataaa
     5941 agttctatac tattcttcca ttgacattaa gcaatagaag tttattcttc tgagtcgctt
     6001 actccattac actcgtcaca taatccataa aatttaacat catgatcaag tattttaaat
     6061 ttgtacaatg attgtatctc tttttctata ttgtctaaaa ggtcttcttt agcttccatt
     6121 atctttccac aatttttaca aataagatga tgatgattat gacagtcttc tttatgtaga
     6181 ctaatctcat atcttataca tccatcgtct aagtttagtt ttgatattaa ccctatttca
     6241 tccaatagtt gcattgttct atatacagta gctaatccta tttcaggaca gtcaacccta
     6301 actaaatcat agatttcctc actacttaga tgtgaatggt catgtttaag caatatttca
     6361 actattgctc ttctttgtgg cgtaatctta aaaccagttt cttttaactt gtcttttaat
     6421 aaatccattg tatttgccat aacatcaccc ttactatttt caattgataa tctttattaa
     6481 ataatattgt aattgataat tcattttttg tcaagacatt taaataaatt taatttattc
     6541 tcataatata aatatgtacc cataaaagat atattattca ccaaaattca taaatttctt
     6601 gatattttta ataaaaaaca aaaaaacaga tatatactat aagtgctttt acaattaata
     6661 aggtttaatt aaagcaaata taataaatac ctgattttta tatacaaact taattattta
     6721 tctagttaag tccatttgat tcatcttcgt cgtagtttaa accctcttct tccattatag
     6781 cagtatatac agctacaaca gtttcatact cttcatcact ttctaaaggt attaagattt
     6841 caccttcttc atcctcatca attctaaaga ttaaagcttc ttcagcttct tcatcatcta
     6901 aaggcattaa tattgcatac tcttttcctt ctgcttctaa tgttaatatt atttcaaatt
     6961 ggctttcaac gccattttcg tctattaaat ttattatatt ttcttccata atgtcattca
     7021 cctcaaattt atttttattt ttattatcta tattatatat cataagtatt caattttata
     7081 gttcttttat gaatttattt taaaatctaa atatccttgc aaaattatta ctgctgccaa
     7141 catatctata accttttttc ttttttgtct actgacatct gcctctaata aagacctctc
     7201 tgctgctact gtggaaagtc tttcatccca aaattctaca tcaataccag tttcttcttt
     7261 taccaactca caaaacttga ttactttttc tccttgtggg cctaaagttc cattcatatt
     7321 ttttggcaat cctgatacaa ttttatttac ctgcttttct tttattattg cttttagctc
     7381 ttcaatatct tttttcttac caaccctttt tattgttttt acaccttgtg cagttagtcc
     7441 catcaaatca ctcacagcaa ctccaatagt tttatcacca acatcaagac ccattattct
     7501 tccatctagc ataattcctc ctttatctat ttatattcca tagattaaat acatattatc
     7561 aatcataaaa attgcaatat gattttctat gtaagcatac agtttacagt aataatcata
     7621 ttgcattttt tatttaaatt ctatatgaac agtaaaaaat tttttagtta tttttttcaa
     7681 atattatcat atttatactt attattatta gtggtataag tatatatata gatgctgtag
     7741 atgcagcaac tattccggaa tcattaacta aaagagtgat tatacaacca accatagatg
     7801 caataaaccc tttaaacaag attggaaaat tattcattat ctttctaaag tgtctagatg
     7861 gtttaaatat aagtactgca attactccaa ttcctacaag taaaatattt acccatacac
     7921 ttgtctgtgc tagttgcata ttcatttgaa tttttcttcc aaatgtttgt aatatctctc
     7981 ctggtccatt taggaaaatt ctttgtacaa acatacctaa atgagattca ctacctgaaa
     8041 ctatatctaa agctgcaaat gcaaaaacaa caactacagc tgaaacagct aataatatag
     8101 ctttcttaaa atctatttta atgtcatata taagcattat aaacaacaaa tatgctacac
     8161 attctgatat agctccacca acatttgcac ccattgaagg atatgcacta gttataagta
     8221 ttattaacga aaaaattaca acatacaatt tagatacctt cttataatgt aataatactg
     8281 ctaagccaaa tactgcactt gctatagtta caccctcata ttcatttcct acaccatagt
     8341 acctagctcc tatgacagca tcataactca ttatgttatt ttgcatcaag tatgttccaa
     8401 atacagaatc tataactatg actaaaatag taagtgttgc aaaaaatccc atgtgtttta
     8461 tatcattgcc cttaaacaat tttctaccta acaagtataa tattagcgta gtcgcaaata
     8521 ttcccaaaga tattgaaatt ggagttttaa aattcatcaa aggagctaac ataaatgata
     8581 gtggcattat tatgcctaat tttataaact ccttaagtac tttgaataca cgctctttat
     8641 gtggcatata atttctaaag aaaatcgcaa acattgcaat tacccaagaa gcagatatta
     8701 cacctacaaa gccatttata atagttgacc ttattgaaga tatagacact atcctttcat
     8761 aaagtgattt tagataatta acgttgtctt ctttatttac taaagtataa cttctaccta
     8821 ccatctcttt attttcaaga ccaaatgtac ttagtatatc cactccaaca tctaagttgg
     8881 caacaattcc agccttcctt gttgtggcag attccagtag acctttccct tctccactaa
     8941 attttattat tggagaaagt cttctcttat tcttataatc taggtcactt ggaaatgcac
     9001 ttgctatata aacagtgtca ttttctccaa ccatagaaaa tacttgttca agatatttat
     9061 ttatattttt tacaatattc ttcttcattg taccataagt attatcattt agatttaatc
     9121 tatacatatc taatctatat gtatctccaa gttctacaaa tatagcatca ctatttttat
     9181 aggatttctt agtttcatct agtaatttat cgtagtctgt agatattcca aatggcattt
     9241 tagaatcttt cttattaata ttatcaatat tacctgaatc aattcttcca tattggtcca
     9301 tagctactag acataaattt ctattcttaa ctaattgatt attttcaatt atatcagcat
     9361 ttccaattac agatgtcttt aaaccatttt ctgataaagt ttttcctaat gaccctaaat
     9421 ttgctccata ctctccatac tcaagatttt catttataga tctattaata cctaaatcat
     9481 ttatttcttt agctttttta cctgttgcga cttcaaaagc tttagcagta tcttggtcta
     9541 ctttttgaaa attgatatag tcttcagtag ttacactagc tcttgttcct gcacccatac
     9601 ttgcataaga ccttctatca tcagtacctt gatcccctct tatattcatg agagctacat
     9661 atcctctctt ttctatctca tttttcaaga ttggaatatt catcatactt ccaagattgg
     9721 tcctattcat atcaataaat atgaccttgc ctttttcttc ggcaaaacca tagctagcag
     9781 ttgatacaaa aatcataatg actattgcaa acaacgacat aatctttttt ctcatttatt
     9841 tgacctactt tctattcaga tagtgcgtga ttacttcttc aagtatctca tctctttcaa
     9901 attttttaat tatagctctt gcatttttat gactagttat atagctagaa tcaccagaaa
     9961 ggagataccc tataatttga tttatagggt tatatccttt ttcaactagt gctttatata
    10021 caaaatcaat agtatctcct acactcatcc tatcttctgg tattccctca aatttcatag
    10081 tgtagtctaa atctttttcc aaactaaaaa cctccttgag tgaatgttat ttaacttgtg
    10141 tcttaataac ctcacttgca tagcttaaag cttggtcaac cttagataca tcactagctc
    10201 ctgcttgtgc catattaggt cttcctccac cttttcctcc agctattttt gcaacttctc
    10261 taacaatatt acctgaatgt attcccttat ctaatacatc tttagtggca gtaactacaa
    10321 agttaacttt atcatctact acatttgcaa gtactactac accagaacca agcttatctc
    10381 ttagattatc tgctgtttct cttagtgtat ccatatccat accttcaaat ttattagtta
    10441 tcaaattaac tccatttact tccactttag aatcaaaaat agaatcaact gactgtaaac
    10501 tcatcttagc tttcatatca tgcaattctt tagataagtt tttattttct tctaataaag
    10561 aacttattct ttgaattaaa ttatcttctt tagattttaa gtttacacaa acttcagaga
    10621 taattccatc tctttctttt aggtattcat aaacagcttt tcctgttatt gcttctattc
    10681 ttcttacacc tgctgctact ccaccttcag ataatatttt aaacattcct acttgagaag
    10741 tatttgtcaa gtgagttcct ccacaaagtt ctgtagaata atctcccata gaaactactc
    10801 ttacctcatc accatatttt tcaccaaata gtgctgtagc tcctttttct ttagcttcct
    10861 ttatattcat aatatcacat tttatgtcta aagatgataa aataacatta tttacttttt
    10921 cttctattac ttttaattct tcatttgata ttgcttcaaa gtgagtaata tcaaatctaa
    10981 gtctttctgg agttactaaa gaacctgctt gattaacatg ttctcctaac acttctctta
    11041 atgctttatg aagtaaatgt gtagcactgt gatttcttgc agctgacatt ctagtttctc
    11101 tatctactag agtctttact ttatctccat tacttatgct accagatttt attataccta
    11161 tatgttttat actattatta gcaccttttt tagtatttaa tacttctaaa actaagtttt
    11221 cattagttat caatccacaa tctccaactt gtcctccacc ttcaggatag aaagtagtgt
    11281 tatctagtac tatagatacc ttatcgcctt cttttgcact ttgaactagc tcatcatctt
    11341 taactatagc ttcaatagtt ccttcaccat aaatttcact atatccatta aatgtactat
    11401 caactgtaga ttctaatttt gatagagggt cttccttcca actttctcca tccatatttc
    11461 ctctagcatt tctagctctt tctttttgct tttccatttc ttcattaaaa gcttcttcat
    11521 ctacagatag atgttcttct tctaatattt ctttagttag gtctataggg aatccataag
    11581 tatcatatag tttaaaagct tcttgaccac ttaggacagt ctttccttca ttttttaata
    11641 cttctatata agagttcaat atttctgttc cttggtctat agtttcattg aatttttctt
    11701 cttctattcc aactactttt ttaatatagc tttctttttc aactaaaact ggatatgctt
    11761 tatcatttac ttttataact tcatctatta gtttctgtaa aaataattct tttactccta
    11821 ataacttacc atgacgagca gcacgtctaa gaagtcttct aagaacatat cctcttcctt
    11881 catttgatgg aagcactcca tcactaacta agaatgttac ggctcttata tggtcagtta
    11941 ttattcttat tgatatatca ttttttggat tctctccata ttttactcct gttaacttct
    12001 caactgcttc tagtatagat ttaattgtat ctacttcaaa gatagtatct actccttgca
    12061 ttatacatcc cattctttca agacccatac ctgtatctat attcttattt tctaataaac
    12121 tataatttcc ttcttcatct ctatcaaatt gagtgaatac atggttccaa aattctaaat
    12181 atctatcaca atcacagcct ggtttacagt ctggattgtc acatccatat tcttctcctc
    12241 tatcaaaata tatttctgaa caaggaccac aaggacctgt acctatctcc cagaaattat
    12301 catctttccc aagtttaacc attctctctt ctgggaaatt catttctttt gcccatatat
    12361 cataagaatc atcatcttct tcatatacag tcacccatat cttatcttct ggtatattta
    12421 accattctgt aacaaattcc catccccatt taattgactc tcttttaaag taatctccaa
    12481 atgagaagtt acccatcatt tcaaagaatg tagcatgtct tgcagttata cctacatttt
    12541 ctatatctcc tgttcttata catttttgag atgtacacat tctcacactt ggaggtactt
    12601 ctacacctga aaagtaattt ttcaaaggtg ccatacctga gtttataagt aacaaactct
    12661 tatcattatt tggtactaaa gaataactat ttgctacata atgacctttt gactcaaaaa
    12721 attctaaaaa cttacttctt atttcattta atcccatctt ttccatatca tgttcctcct
    12781 aataaatttt attttttcgt ttaaataaaa aacctcgtcc ctataaataa atttataggg
    12841 gcgaggacaa tcgcggtacc accctaatta tcatacaaag tatgatatct tcggaaaacc
    12901 ttagctataa cgtaactacc gtcaatctct acttaaatat tctttataaa agataaattg
    12961 ttcaagattg ctactaaaag gctgcttcaa atatcatatt ctaagggctt ccagcatttc
    13021 cctctctctg taagacatca aatattttac tattccttat cactgtattt gttttttaat
    13081 taatatacta attatattac taaattttac aaaattaatc aatactatat tttcatatac
    13141 aataaattta ttttataaac tttatttact cttaatatac cttattgttt atttttttaa
    13201 ttttttagat gtttttataa acttttctcg attatacctc cacctactac aatatcttca
    13261 tcatacatta ctacagattg acctttagta atagctcttt gagcttcatc aaaaactatt
    13321 ttaatggtat cttttcctac tctatgaata gtagctggtg atggctttgc tgaatatctt
    13381 attttggctt ggactcttaa tggctcttct aacgtatcta ttgatataaa gttaacatct
    13441 ttggcaataa gttccttttt aaataaattt tcattatctc caagaactat ggtattgttt
    13501 attggattta tgtctattac aaacattggt tttccaaaag taattccaag cccttttctt
    13561 tgacctatag tgtaatataa tatcccctta tgctttccaa gtatattgcc tttagtatct
    13621 acaaaaaaac cttcttcaat acgcttttta gaatgttttt ttacataatt tgcatagtca
    13681 ttatctttga caaaacaaat ttcttgacta tcaggcttat tgtgtactgc catacccatt
    13741 tctttagcaa tttctcttac tctatctttt tcatagtcac ctattggcaa taaagtatgc
    13801 tctagttgct cttgtgtaag gttataaagt gcataagttt ggtctttttt atctgtaaca
    13861 gattttttta acaaatatct tcctgtactt tcatcctttt ctatctttgc atagtgacct
    13921 gtagctacat aatcacaacc tatttgtcta gccttcttat aaaaatcatc aaattttata
    13981 tgtttattac aagctataca aggattagga gtttttcctt ccaaatattc atctataaaa
    14041 taatctatta ctttttcttt aaagacttct ctaaaattta aaacataaaa tggtatacct
    14101 atcttatttg ctacccttct agcatcttca acagcagata aagagcaaca accaccttca
    14161 atttcaacat cgtcatcatc ttgccacaac ttcatagtaa caccaatgac atcatatcct
    14221 tgttgtttta aaagatatgc agctacagag ctatcaactc ctccactcat acctatcatt
    14281 acttttttat tcataaacaa atttcacctc atcttttgca ttacttatta ttatatcata
    14341 tagaacaaac attgtattta tttaaaatat agcttgctct attttataaa aaaaataatt
    14401 attttcatta tctaaatatt atagaaatat attttgttaa ttaattgact tctaaaacaa
    14461 gtaaaaacta ttaatttaag caataaaaaa tagctatttt acaaacagct attttttata
    14521 tctcattaat acttcttttt agtcatttta aacttctcat aacacaatta cttattttta
    14581 ttcttcttct tcaacatcat ggtcatgagc atcatctata acatacccat ccaattctgg
    14641 tatatggata ttgttctttt tagcatagtc tataagagct gcttttacag cttgttctgc
    14701 taaaactgaa caatgcatct ttactggtgg taaaccatcc aaagcttctg caacagcttt
    14761 gtttgtaagt tctaatgcat cttttatagt ttttcctttt atcatttcag ttgccataga
    14821 agaacttgct atagctgaac cacagccaaa tgttttaaac ttaacatcct ttattacatc
    14881 tccatctatg tctaaaaata tcttcattat atctccacat gtagggtttc caacttcacc
    14941 tacaccactt gcattatcaa tttctcccat atttcttgga ttcataaaat gttccataac
    15001 tttatcacta tattgcatta tcttttcctc ctactcaatt tatgtctatt ttttatgctt
    15061 tatctttctg tctattttac taaaccttgt ttcttagcat catcataaag tggtgacatg
    15121 cttctaagtc tttctattac ttttggtaag ttctctagta tataatctat atcatcatct
    15181 gttgtaaaat ctccaactgt aagtcttaat gaaccatgtg ctatttcatg tggtaaacct
    15241 attgcaagaa gtacatgtga agggtctaat gaaccagaag tacatgcaga accacttgaa
    15301 ccagcaattc ctaacatatc taataataaa agtattcctt caccttctat aaattggaat
    15361 gcaaagtttg catttcctgg caatctattt tctaagctac catttactct tgtataaggt
    15421 attctttcta acacaccatc tattaactta tttctaagac gagttaaagt ttctacatga
    15481 ttttgcatat tttccttagc taattctgct gcttttccat atccaactat tgcaggtata
    15541 ttttctgtac cagctctttt gcttttttct tgtgctccac catggacaaa gttatgaagt
    15601 cttacacctt ttcttatgta taaagctcct acaccttttg gtccatatat tttatgtgaa
    15661 gacatactca ttaaatctat tcctaattct ttaacatcta ctggaatatt acctgtagct
    15721 tgtactgcat cagtgtggaa taatatctta tgttttttag ctatttcgga tatttcttta
    15781 ataggctgta tagttcctat ttcattattt gcaaacatta tgcttataag tatcgtagta
    15841 tcttttattg aatcttctag ttgtttcaag tctacttttc cttcgctatc aacatctaaa
    15901 taagttattt caaatccatg atgttttgct aagtattcac atgtatgaag tattgcatgg
    15961 tgctctattt ttgaagttat tatatgatta cctttgtttt tattagcata agctacaccc
    16021 tctagtgtcc agttatcact ttctgaacca cctgctgtaa aatatatttc actaggttca
    16081 gcatttataa gggctgctac ttgttctctt gctttatcca aagcatcttt tgcttctctt
    16141 ccgaatgtgt gaaaactaga tgcattacca aaataatctg ttaggtatgg catcattgca
    16201 tccaatactt cttttttaat aggtgttgtt gcagaataat ccatatacaa tcttcttttt
    16261 tccattacat tcatctccaa atctattttt taatatttgt tatatcattt tctaatttat
    16321 ttttgttata gtcatttatc atatctttaa gagtaattga atctataaca tcttctatac
    16381 cctttttcat cttttcccaa actatttttg ttacacacat gtttgagttt tcacatacat
    16441 cttcatctag tacacagtca gataatgcaa ctggcccttc taatactaca agtatatctc
    16501 ctactgttat gtcttcagca ttctttgaaa gcaaataacc tccttgagcg cctcttacac
    16561 tttttactag acccgatttt tttaaagatg aaaatatctg ttctaagtac tgatctgata
    16621 ttttttgctt cttagcaata aattttaatg acactggtcc attgtcttga tttaatgcta
    16681 attcaaacat tgcttttagt ccatacctac ctttagtaga caacttcata tattatcacc
    16741 tctatataga aatctaattc atactgtttt agtaggaatt actttcaaga taattttatt
    16801 ataccctact aattttgtca agattaattt taatttttta ttttgaataa attccccatt
    16861 ttccaatgtt ttcaaatcct agttttttat atatctttcc agcctcttca ttatcataaa
    16921 acaggcaagg aattttgttt tctctcaata actctgaaca tagtttaatt aggcactttg
    16981 tggcaagccc tctagctcta tatttaggat gtgtccctac tccaattatc attgcatgag
    17041 tcctattttc tgaagtactc tttgccattg acactacttg tttgttaatc tctatacaat
    17101 atcctctacc tgtccttagt ccatttttta aattctctaa agttgtactg tgaaactcat
    17161 ctattaaatc ataaagtttc actgtctttt ttagatttcc aagcctaatt ctcttaacct
    17221 ttgcattaca attattatct atcaaaaact ttttagtttg aagtttgcaa aaatcaacta
    17281 cctttaaatt attaagtcct aatctctttg ctaaagcatc tacagcacat attttaccag
    17341 atatttcttc ataattagta ttacgaagta gattgtaaaa accttcaaca tcatactctc
    17401 catcagaata aaacatcata aattcaaaat atttaagtaa tattgccttt atttcaccaa
    17461 gttcatctat atctgcccat atattcaaaa aattatttcc atatccatat ctttcaatat
    17521 cccctattat aaacaaattg tactcaggtt ctttttttaa gtatttcata actctactgt
    17581 gataagttga gttaagtttt ataatcataa tatctacccc cgatacataa agttcagtct
    17641 aaaaatctcc atctagatac tctaaatatt tttttatatt tttctcagtt ttattctctt
    17701 gtggtatgta atagacacta tcttttatgc tatctggtaa atattgttgt tttacataat
    17761 gatttttaaa attatgagga tatttgtatc cacaacccct acctatttct ttagaaccag
    17821 aataatgagc atcttttata ctatttggta tatccttaac aaactcttta tccagttcat
    17881 ccatagcttt cattattgct atacatgcag aattagattt tggagatgta gccaaaagaa
    17941 tagtagcttc tgctaatggt attttcgctt ctggaaatcc aagttgcata gctgagtcta
    18001 cacatgcctt tacaattaca atagcgtttg gataagctaa acctatatct tcactagcta
    18061 ttactaaaag ccttctacaa atacttatca aatctccacc ttttataagt cttgctagat
    18121 agtgtataga tgcctgtggg tcacttcctc ttatggattt ttgaaatgca cttaaaatgt
    18181 cataatgact atcaccattt ttgtcatagt ttataatctt attaaatgta gatgccttta
    18241 ttatatctga atctatataa gttatattat ctttatttgg tttagttgaa taaaccacca
    18301 cttctaaaat atttaaagct cttctcatat ctccatcaga aagaatggct atatactcaa
    18361 tagcatcctt attacactca atatccatat aactatcttt atttaatact tcaacagctc
    18421 ttttcagccc tttttctata tcaatttttt ctaaaggttt aaattcaaat acagtagacc
    18481 tgcttaaaag agctttgtat acataatgat atggattttc tgttgtgcta gcaatcaagg
    18541 ttatactccc attttccata aattctaata ttgattgttg ctgtttttta ttaaaacttt
    18601 gtatttcatc tatatataac aagactccac ttatattatt tatacttcca agttctgata
    18661 tcacattttt tatatcttct aaagatgaat tggtagcatt tattttatag aaatttttat
    18721 tacttctttc tgctattatt tccgctactg tagtcttccc aacgccagga ggaccaaaaa
    18781 atatcatatt tggtaaaaaa ttagattgta atatcttaga caatattttt ccattaccta
    18841 ttatatgact ttgacctatt acatcattca ttgtttttgg tcttatttta tctgctaaag
    18901 gcattttctc actccttttt aataaaaata cttactttgt ccttacctca ataattcgtc
    18961 taaaaaaggt atctatttga aatagatacc ttttctaatc taaacctata aaatatagat
    19021 tattgattgt tttttaattt ttttaattca tctgtgagtt tgtcattaag tattcttata
    19081 tgagtacctt tcatacctaa tgatcttgat tctatcacac ctgcactctc aaattttcta
    19141 agtgcattta ctattacaga cctagttata ccaactctat cagctatctt acttgctaca
    19201 agtaaacctt ctttgccatc caattcagca aaaatatgtt cgactgcttc aagctcggag
    19261 taggacagag tgcctattgc catttgaact acagctttct ttctcatttc ttcttctaat
    19321 tcttcaccta ttgctcttaa tatttcaaga ccaacaacag ttgcactgta ttcagctatt
    19381 actaaatcat catcattaaa tgaatttgaa tatcttgaaa gtactaatgt tcctagtctt
    19441 tgaccgcttc ctaatattgg aactactgta gtatattttt gtaatcttcc atgttcttca
    19501 ggaaagattt ctaatatctt ctcaccattt aaattttcta atgtttcatc gatttttaac
    19561 acattttgag tatattcatc tgaaaatttc ttttgcttag tatactcatc ttctataact
    19621 gaactgtctt gagcatcatt taaatgaaga cctagtactt taccttttgc acttactaca
    19681 taaacattag aacttaaaac gtcgcccaat gctccggcca gtaaatcaaa agagacactg
    19741 cttccaccac ttgtttgtaa tgttttattt attttccttg ttttttgtaa cacttcactt
    19801 gccatttaat catctcctca tgaaatttag gccttttaat aaccttttat attttctaat
    19861 attattttca catttaatga aaatttattt ttctattagt tgtttacact tgaaagatta
    19921 tcatagattg gaaccttttt caagagaatt atgtgatttt tttcaatttt cactcttttc
    19981 cgtcattatg ctcttttgtt tctttattac attctttatt agaacacact gtttttgttt
    20041 cagatttagt cactttttca accatatatg aaccacactt ctcacaaaac tctcctgttg
    20101 gcttgttcca agctacaaag tcacagtttg gataattaga acacccataa aaagctttac
    20161 ctcttttaga ttttctaagt ataatatctc cttcttcaca ttttggacat ttaacaccaa
    20221 ttttattcat aattggtcta gttgttttac agtcaggata gtttttacaa gccataaact
    20281 ttccaaatct accatatttg ataaccatat tagaaccaca gttctcacaa atctcgtcag
    20341 tttcttcatc catatttacc ttttctatat tttcaagagc ttcttcaata gcctctttaa
    20401 gaggtgcata tgattcagat acaatctttt tccaatctgt attaccttct tctataacat
    20461 caagtttact ttccatatca gcagtaaaat ctacatctat aaatttatgg aaattatttt
    20521 ccaaaatatc agtaactatt attccaagtt ccgttggaca tagacttgtt ccttgctttt
    20581 caacatattc tctattcagt atagtagcta ttgttggagc atacgtactt ggtctaccta
    20641 tacctagttc ttctagcgtt tttactaaac tagcttctgt atatcttgct ggtggttgtg
    20701 taaaatgttg gtctggcaat atattttcta tatttaatat atctcctttt tctatacttg
    20761 gtaaaatttt gtcttctctt tctgaaaaat tatatacctt agtataacca tcaaatttca
    20821 tttttgaacc agttgcttta aatacaatat ctcctatttt acattctaca tttagtatat
    20881 caaatattga atcttccatt tgactagcta caaatcttct ccaaattaaa ttgtataact
    20941 tgtactggtc tttgctcaat gaggccttta tactatcggg agttctatca actgaagttg
    21001 gtcttattgc ctcatgggca tcttgaacct ttttagcatc ctttttttct tttttatcac
    21061 cagtgttttt atagtagttt tctcctagat tgtttactat ataaccctta gctttttctt
    21121 ttgcttcatc agatattctt ttagagtctg ttcttatata tgatataaga ccaacagtac
    21181 cttctccttc tatgtcgata ccttcatata attcttgtgc tatcatcatt gtttttttag
    21241 tagtaaaaaa taacttattc gctccttctt gttgaagcat acttgttgta aatggttttg
    21301 gagctgattt acgtcttgat ttagattcta tcttctcaac ctttaaatct ttaccttcca
    21361 tttcttttag tatttcattc acagcttctt catttgctaa ttcaattttt tcatcatttt
    21421 taccataaaa ttttaaagtt atatctttgt cttttactgt cttagcctca acatctattg
    21481 tccaatattc ttttggaata aatgctttta tttctttttc tctgtcacaa attaactttg
    21541 ttgtaacaga ttgcactcta cctgcactaa gaccttttct aaccttttgc cataatatag
    21601 gacttatttg ataacctaaa agtctgtcta gtactcttct tgcctgttgt gcatcaacca
    21661 aatttatatc aatatttcta ggatgtttaa ttgctttttt aattgcatcc ttagttattt
    21721 cattaaactc tattctacaa tcctcagatt catctaaatt taatatatga gctaaatgcc
    21781 atgatatagc ttcaccctct ctatcagggt cagttgctag atacacttgt ttagattttt
    21841 tagcttcttt ttttaattcc tttattacat cgccttttcc tcttatattt atatattgag
    21901 gttcaaaatt attttctata tctacaccta atttactttt aggtaaatct ctgacatgac
    21961 caactgatgc tttaactgtg taatgacttt tccctaaaaa tttttctata gttttagctt
    22021 ttgcaggcga ttctacgatg actaatgttt tggccataaa accatacacc cccactacct
    22081 aatcttaatt tatacattta aactgtacgt tttattattc atttctacta ctaactcatt
    22141 tagtactaat tcattgatta ttgaatttac atactttatt tctataccag tataatcaca
    22201 aatactatct atatgcaagt ttccttctct ttttatagct tcaattattt gcttagactt
    22261 ggcatttaga cttatattat catatttttg atttattttt ttatcaataa tattaaatat
    22321 gttatattca tttaaaatat catctatatt ttcaattaat tttgcccctt cttttataat
    22381 tttatgacaa cctctactca tttgagaatt tatattgcca ggtattgcaa aaacattttt
    22441 tccatgttca agagcaaaat ctactgtgat taatgcacca ctttttattg ctgcttctac
    22501 aacaactact ccatcactta agccactgat aatcctattt cgattagaaa aatgatatgg
    22561 ggctactgtc gagttaatat tatactctga taataataat cccccatttt ctaatatttt
    22621 atttgataaa tgtaaatttt gttttggaag aggattgtct actcctgaac caagtactgc
    22681 tatagtttta gattttccac tcatacaacc tatgtgcgag tatgcatcta ttcctatagc
    22741 taatccactt actatattaa ctccatattg ggatagttga caacttattg tttttgcaca
    22801 attaattcca taggctgtag gttttcttga acctactata gctatattaa atttattatt
    22861 aactaaatct atgtcacctt tatagaataa taactttgga gcgttgtata tattctttaa
    22921 attttcagga tattctttat catattgaca aatatattta atcgcttttt tgtaaagtag
    22981 ttcttttata ttttctaaat aagcgtgacc tctatatttt actatatttt ttctaatatt
    23041 caagcttata ttttttaaat tatatatttc tttttcagaa aaatcaaata tatcttcaat
    23101 atttactatt tcattttcta ttatttcaat tgtttttgtt gttattccac caattgattt
    23161 taaccataaa taagtatctc ttttttccat aaaatccacc tcaaaacact atctaaaata
    23221 gctataataa gcctttctaa atgaaaaagc ttctataata cactgtgaat ttatcaagtc
    23281 tctttcttct aaatctgcta ttgtccttgc catttttaaa agttttgtat aacttctact
    23341 gcttaggttg tatttattaa atatcatctc agccgttttc gaagcttctt tttccagttt
    23401 acaatatttg aataaattgt aagctttaat ttcactatta ttttttatat tatctttctt
    23461 aaatctgttt atctgtattt ttctagcatt ttctactctt ctctttattt tttgagaact
    23521 ttcttcttgt tttaaagaat taaaatctga atattttata gaattaactt ctacaaaaat
    23581 atcaaaccta tctaacaatg gacctgatat tttatttatg tatctatcaa tttcgttact
    23641 tctacatctg cactctgttt ctgacatata ataaccacat ggacatggat tcatagctgc
    23701 aattaataat actctacaag gatattttgc actgtacttt actctagata tatttacata
    23761 tccatcttct ataggttgtc tcaaagtctc aagtattttt ctatcaaatt cagctatctc
    23821 atctaaaaac aagatacctc tatgtgctaa agcaatttcc ccaggtcttg catccattcc
    23881 tcctccaatt aaagattgct ttgtagttgt atgatgaggt gctctaaaag gtcttttatc
    23941 aattattcct ttagtttcat ttatcatacc caatatacta taaaccttac ttacttctat
    24001 catttcttct atacttatat ctggtaaaat tgtccttact ctttttgcaa tcatagtttt
    24061 tcctgaacct ggaggtccaa tcataaacat attatgattt ccagctgctg caatttcagc
    24121 actcctcttt acaaagtaat ttccttttat atcttcaaag tcttcattat atttactttc
    24181 ttcatcatta atcttagtat atttgaagtc tatataacta ttatcttttt ctaattcttc
    24241 attctctttt tttgacttat cattcaaaaa agacattatc cttactttat cgacttttat
    24301 ttcttcgttt aaaaaatcga cacattcttt taaactctta ataggaatta tgtcaatttc
    24361 atctacaaat agactttctt ttatgttctc aattggtata aaaatacgct ttattttctg
    24421 agtttttgca cccataatta taggcaatat acctcttact tttcttattt ttccatctaa
    24481 tgataattcg cctataaaca tactttctct tatgtaattt tcatcttttt ttattaactc
    24541 tcttaaaaga cctatactta tagataaatc taaaaaagct ccttcttttt ttatatctgc
    24601 tggtgataaa tttacaacta ttctcgtgct tggaaattta tatccactat taagaattgc
    24661 tgactttact ctttctcttg cttctttaat ttctttacct ggaagaccaa caatattaaa
    24721 actagggatt ccattgctta tatctacttc aaccttaact aaaaagctgt cgattcctac
    24781 taagttactt gaattaataa tacttaacat atttaatcct ttccaaaaac attatctttt
    24841 ttaaaaagca ttcactatgt gatttattct tttttctaat aagtatacct ctataacatc
    24901 aaatcttacg ggagtattat ttaagttatt ttttataata taataatttg caattccaat
    24961 tatttttttt ctttttttgt aacttacaga ttcacaaggg tagccaaact ttatgttaga
    25021 ccttgatttc acctccacaa atataacttc tcttcccatt tttgctatta tatctatctc
    25081 ccctatcttt aatctgtaat ttttttctag tatccttgct ccttttgata gcaaataatt
    25141 aactgctatt tcttctccaa aatcaccttt ttctttatta ttcatgattc actccaatac
    25201 attaaatttt cacttttaaa ttatggtcag tatacaattt tactattcaa tttttgggat
    25261 tgattttatt tctatcaata ttattaaata cttctattga ctttattctt ttatgatatt
    25321 attctagttt tcataggaaa agtttatttt tttggaggag tgcctttaat gaacagaaaa
    25381 aaattagttg cttttatacg atatttatct ttatttatat tagttgtaag ctatttgaaa
    25441 aatgttgaaa acacattgta tccagtcata atcatgatga tattatttat aattataata
    25501 aataatcaag ttagattttt ttctttatca aatgagaata aatttatact tatttcttac
    25561 tttttagaac ttatattaat ttttatactg tgtaattata caaaaacttt taattcgatt
    25621 tactttgttc ctttaatatt agatatatca tttttaataa aggaaaaata taagtacata
    25681 ttgttcactt tagttataat atcttctctt attattagtt tagataaaaa tatatatttg
    25741 gcactggaat caagttctgt attactaatt ataactatac tttctatata tatagaaaat
    25801 gagaatttat caaaattata cagtcaaaat ctttatgata agcttagaat ttccaaggat
    25861 gaattaaaaa aggttaacgc tgatttggaa acttatgcaa gttctataga agaattagca
    25921 attttaaaag agagaaatag aatatcaaga gaaatacatg atagtgtagg acattctctt
    25981 tctacaacaa taatacaatt aaatgctata gaaaagctcc taaaagacaa gcctctaatt
    26041 tctgaattag tacatgaact tagagaattt gtaactgaaa gttttcaaga tgtaagaagg
    26101 gctatatctg agttaaagcc tgttgaatat gaaaattacc aaagtttatt taaaatcaaa
    26161 gaactagtta aaagctttat taagcttaca aatatcaatg ttaaattaac tatttcaaaa
    26221 aatacttgga acttatctag aaatcaatct ataggtttat atagacttat acaggaatct
    26281 ctttccaact catcaaggca tggaaaggca actgaaatca aaatttttat gacattcaat
    26341 ccttcaaatt ttataattac tattagtgat aatggtatag gatgtggcaa tataaaaaaa
    26401 ggaaatggac ttaatagtat cagtgaaaga atatatgaat taaatggtaa agttgaattt
    26461 gataattcta ataatggttt cacaattaga gcttcttttc ctaaattttc aggaggtgat
    26521 ttttttgaat aaaatcaaag ttcttatagt agatgatgaa aaattaatta ggaaaggtct
    26581 taaaattata ttatcatctt ataatgattt agaaattgta ggagatgctt ctaatggata
    26641 tgaagcttta gaattttgta aaacgaatga tgtagacata gttcttatgg atatacgtat
    26701 gaaagtatgt gatggagttc taggtacaag gcttataaaa gaatataata attctataac
    26761 attattaatt ttaacaactt ttaatgatga tgaatatata aaagatgcta tgaagtttgg
    26821 agcttcagga tacctattaa aagatagctc tgatgaagta ttgcatgaag ggattcgttc
    26881 ttcatttttt ggcaatattg tccttgataa aagtgtagct gaaaaaatca tgacccctga
    26941 aaaaatgatt gaacaagagc atctttatga catgtacaat ttaacagaaa aagaaatatc
    27001 cataattaga ctaattgcaa atggacttaa taataaagaa ataagtaaag aactattctt
    27061 gtctgaaggt acaataaaga ataacataac taatatttta ggtaaactag aacttcgtga
    27121 cagaactcaa ctagcaatct ttgctttcaa aaataaaatt gtaatagaat aaatttaaaa
    27181 atataaagtg acttaagtca ctttttttag tgacttatag taatagaatt ataattcata
    27241 attctttatt atagtattat agatttttaa cttatacaaa attattttgg aggaattatt
    27301 atggatatag tcagagtaaa taatataaca aaaagattta atgataaatt agcactcgat
    27361 aacatcagct tttctgttaa aaaaggtgag atatttggac ttattggtcc aaatggtgca
    27421 ggtaaatcta cacttataaa tataattaca aatcttatgt taccaaatag tggtagtatt
    27481 caaataaatg gtttagattt atcaaaggat tatataaaag caaagtctat aataggatta
    27541 gttccacagg aattagcaat tatagaaact ctcactcctt ttgacaactt agagtacttt
    27601 ggagctttct atggtttaaa aggaaattta cttaaagaaa gaatcaatga agcattagaa
    27661 gtcacaggtc ttactgaagt caaaaagaaa aaagtcaaaa aattatctga tggtatgcaa
    27721 aggagattaa atattggaat agcactctta aatcatccta aaatattaat attggatgaa
    27781 ccaactgtag gtgttgaccc ccaatcaaga aatcatattt tcaattttat aaaagatatg
    27841 tctaaaaaat atgaaactac tgtaatatat acttcccatt atatggagga agttgaacat
    27901 ctttgttcta aaatttttat tatggatgaa ggtaaagaga ttgcttttgg agataatgct
    27961 tatttaaaat cgctagtatc tacaaataca aaattaatta tggaaataaa aaatataaat
    28021 gctcaactta tctttgattt aaaaaatact aaaggtgtta tatctatttt agaaaataat
    28081 tcattattag aattggatat agataaaaaa ttacaactta cagagatact ctctgtcatt
    28141 gacaaaaaca actcaaaaat aataagaatt tcttatgaag aacctaatct agaagacgta
    28201 tttttaaatc taacaggaaa aaatttaagg gactaatgga ggtaatttta tgaaattata
    28261 catgagtgta aaaactatgc taaagggttt aaaaagctcc tttatactta atttaatata
    28321 ttttttagct ttacctctga ttttatcttg gtttcttggg atggttacag aaagcatgtt
    28381 tcaaaatcct ataaaaacag aatctacacc cattgttata tatgacaaag acaacacaag
    28441 attatcaaat catttgacaa agtatttgaa aaatgattta tcttatatat taacagttaa
    28501 aaaagatgat tctaaggcag aattaaagct tactatacct aaaggctatg agagtagttt
    28561 attaaatgaa aaatcaaata ctctaaatat agaaaaactt ggaactcgtg atgatattgc
    28621 aatattgctt caagacatat tagatactta ccatgaaaaa ttttatttaa ataattccca
    28681 gaaaataagt tcagaagatt tctctaaatt atttaataaa aattctattg atacttctat
    28741 aataggtaac aatgttaaac agagctctta tgaatacttt gctttagttt cgctagggtt
    28801 tcttgtaata atctttataa tgaacaatat tttatcaaat tatataagcg aatcaaaagg
    28861 actctcaaaa agactttatt ctatgcctat aactagagta caattcttaa tttatgactt
    28921 tgtaggttta tggatttatt catttatatt cttattatta tatgttttat tctttagaat
    28981 aattggaata acatttaaag gtaattttgc catattgctc ctactttgtg ctttatcatc
    29041 ttatttcatg acttcaatat ctacttttgt aaacagcttt tttagtaaaa aatatggtac
    29101 aataatagtt tatgcattac tctttttaca gacaattttt ggaggtatct ttagtatgat
    29161 aagtgatgca tttactaagc ttacaagttt atctcctacc tatttaatag gagaattgtt
    29221 tagtaattat gaaacattta aaactataga ttcaatagga aatttaattt tcacatgttt
    29281 aattacttct acaatattga ttgcacttgc tattgtaaag gaaaaatata aatggaggga
    29341 ggttcaataa tgattagatt aactgttgca aatataaaaa gatatctaaa aaatcatact
    29401 cttttaatta atatggttat gcttcctatt atactaattt tttcacttaa tttttttatc
    29461 aacaactcgg gaaatcaatc aatgtacttt tctccagtag caattgtatc tgactcttca
    29521 ggaaagtatg aacataagtt aataaatagt tctaagttaa aagaaaattc atttagatta
    29581 aatgaacaag ataaggctat gaatctatta aaaaataata aggtttctgc tgtattcgtc
    29641 ttagataaaa atttttcaaa tagtatagat aacttacaac gacctgtagt taaatgcttt
    29701 aaaattgaaa atggtggtgg tagtctttgg gcagaatcac aaatagaatc ttttattact
    29761 aaatcgttaa aattgaaaat ggataaaaat atagatgata aattgacaaa gacaaatata
    29821 attgataaca aactagataa gaataaaggt tcatttttag tagtcttctt gatatgctat
    29881 tttatgtata ttaatgcggc acatcttgct tctgatttat ttacattaaa aaaatcaaat
    29941 gtgctaaaaa gacttatctc tacagataat aaagatataa aaataatttt cagtatattt
    30001 ttagggttat tttttattca atcaattgta tacactttta ctctattatg tttttcaatt
    30061 atagaagact ttaatttaag tctgaatgta ttgatgattg tactagcaaa tagttttgtt
    30121 tccactggat ttgtattttg gatagctaga gtatttaaaa atgaaagttc tataagtctt
    30181 atatctacat tttattcttt aataggtttg gctatatctc tatctagtct aataccatca
    30241 atggataaat tatcatttat ggctaatctt tcaaaactta caccatttta ttggactata
    30301 gatgctatta aaaacaatgg tagtatctta ataaatataa taattctgat attgattgga
    30361 actatatttg taactgcagg aagtcttaag ttacgagatt ttgctaaaaa ctagtagtta
    30421 ttaaatataa ttagtattta tttttatata atgataaaag aatattccaa catgttaaat
    30481 cattttacct tatatttttc tatttagttt tatataccat ataacctaaa cttaatatta
    30541 tatattaaca tttttgactt gtcaagtttt ttatggtata atattaatta ttagataatt
    30601 aatatactgt acctaagttg caatatctaa aattcagttt ggaggtataa ctaatatatg
    30661 tataaaattg gtgaaagtgt gatgtatcca aaagagggag cctgctgtgt aaatgatatt
    30721 gtaacaaaga aaataaatca tcagatgcaa aaatactatg aattaagtgt tattttcaat
    30781 agtaacctta aaatttcgat tccagttcta aatgcagaca ggattggaat acgtccagtt
    30841 atggatggaa atgacgttga taaatttatt caatctattg ataaaacaga tggtgtatgg
    30901 gtttttgata gaaaacaaag gcttaaactg taccatgata aatttcattc aggagatgtt
    30961 tttgagattg taaaattaat taaaatgctt atgatacaag actgttcaaa acaattgtgt
    31021 agtacagata aggagttttt aaataaagct caaagatttg ctttatcaga attggctgct
    31081 gctcaatgta aatcttatac agtagtatta gaagaaatga aaaaacatat actaaattct
    31141 aaaagtaaaa attaaaccag tcttaaagac tggttttatt tttatactaa tcatttatgc
    31201 tactctatct tactttaaac tgcctaatct aatattaata aggttaccct aagtagatag
    31261 atgtctttat tcaaataaaa aaactaagag taaatcatat tactggttta ctcttagata
    31321 ataaaactta atcttcttca agttcttttt tctcttgtaa taatacactt aattcatttg
    31381 cttctaaaac ttgtgcctct gcaatatcaa gtaactcttg ttgccattcc acacatttat
    31441 ctttgtaatc aaaaggtagc gttctgtcaa ctatgtactt atcaatacag tcctccgcac
    31501 ttttaattat ttcttttctt tcatcaataa atttttctaa ttctactaag gcttcttcat
    31561 aagcttttct actcatataa attccccctt tgtacaattt attctacatt aaaacgattt
    31621 ttcctctttt ttgtataaaa ttttatttgt atataacttt tccatcaata tcttttatag
    31681 tttgacatcc agttaatatc atagagctac ttagctctga ttgaagttta tttacataag
    31741 tttctacacc atcagttgca ccaccaaatg aagcagtcac aaaaggtctt cctattaata
    31801 ctgcatctgc acctaaacct atcattttta gtacgtctaa accagttctc actccaccat
    31861 ctgcgagtat tgtaacttta cctttaacag catccgcaat ttttggtaaa acttcacatg
    31921 ctcctggtgt acaatcaagt actcttcctc catggtttga tacaactatt gcatccacac
    31981 ctgcttctac tgccattaaa gcatcctcaa cagtcattat acctttcaat ataaatggta
    32041 gtttagtaga ctttactaac tcttttattt gttcaacatt tttaggaagt actggttttc
    32101 catgtagtga taaagttact agaccgcaag catctatatc aactccaact gcaaatgcac
    32161 ccgcttcttc agctaatctt atctttttta taatattttc attatcccaa ggtttaataa
    32221 atacaattcc agctccatta tactttttaa ctacatctaa attttccatt aaaaaagcat
    32281 ctactgctgt atcaccaacc attgcataaa taccactatt agcacatcct gcaactactg
    32341 gttctatgta atctctttca ttaatttttc cacccatatt taaagtagtt cctgttactg
    32401 gagctgcaaa tataggtgca ctcattttct ttccaaacat ctctatagat gtatcaggat
    32461 ttgatacatc atgtattact ctcatattta cttttacttt ctctaaactc ttgctatttt
    32521 ctataaaaga agaaccactt cctttacctc ccatgccagg tacttcgcct gcacaagcaa
    32581 ccccattgca aaccttacaa actttacaac ttccatttaa attttctcta gcatttttta
    32641 ataattcatt atattccatc tttaatcccc cattaattat agtaatttat attatataca
    32701 ttatatcata ttatatttac agtatatttt tcaaaaaact ttttctgtgg ataggagtta
    32761 tgccatattt ttcaatagct tcatagtgtt ctttagttcc gtatcctttg tgagatttaa
    32821 atccatattc tgggtatact ctatcatatt ggtacattat actatcccta gtaactttag
    32881 caagtatact tgcggctgct attgatatag attttgaatc tccttttaca attggatttt
    32941 gagctatatc aatacctggt attgttgctg catcaactaa taaataatct ggtgcttttt
    33001 ttaaacaatt tatagccttt ttcattgcca tatatgtagc atttaatata ttaaattcat
    33061 ctatttcttc attgtttact atacctattc cataatctag tgcttcctct tttattactt
    33121 caaaaagttc atctcttttt gcctcactca atttcttaga gtcatttaca ccttctattt
    33181 ttgtatcttt tttaaatact acaacagaag ctacaacagg tccagcaagt ggcccccttc
    33241 ccgcctcatc aattcctcca atatataaat agcctttatt atagccttcg ttctcaaata
    33301 tatttatagt ttctaatctc tcttcttctt ttctaatatt atctagtttt tttgctagtt
    33361 ttatagctaa accttgtaca gattttcttt catctaccct taatagttct atatattcca
    33421 tatatttttc tacttctaaa gtctctatta tttctttaat ctccctcaca cttttatcct
    33481 gcataccatt cccccatctt tcgtttttaa aaatttaagt tttaaacata ttaaaatttc
    33541 ttaattagag tttaattgca tccactataa ccacatttta aacatatact acatccacct
    33601 gtatgtgcaa ttccttcact tccacactca gggcacacaa atttttcatc ttcttcaaaa
    33661 tttttattta ttatttcttt ggctttttca tctttattat ctttttcttt tttattattt
    33721 ttataatatt cttttttact attttctttt ttattttctt tattattttc ttcctttttt
    33781 tcatttatta aaattccact ccttttacat ccatctctaa atattgttac tcctttaaga
    33841 ccagcctccc atgccttaat atatatattg aaaacatctt caactgtagt ttcaaaaggt
    33901 atatttattg tagatgatat agaagcatca atatactttt gccatacttt ttgcatgttt
    33961 attctttctt catatcctat attcatagca gtaacaaaaa aatctggtaa acattcttca
    34021 tctgtaatac ctttcttatc catatactct ttaacaattg gagtatatac tttatagtac
    34081 acatcttcat catgtaagct ttcagttttt cttatatatg aaagattaaa tataggttct
    34141 attccaccac taatacctat cattgtagat atagaacctg taggaggtat tgttaaaagt
    34201 tgtgagtttc taagcccata ctttttaacc atttccttag tgtcttcatt taaattttct
    34261 ataaaaaact tagatttaga aatattttca tatttatact cactaaaagt gccatattct
    34321 ttagcaatta atgctgattg ctttacagct tcatttaaca tagtcttacc aattaaatca
    34381 cataattcta aagattcatc agagccatat cttattccca tttttataag catatcagct
    34441 atacccatta cacctaaacc tatctgtcta tatttatgta cactatctct ttgttcttgt
    34501 aatgggtgca agtttaatcc ctcatctaag acatcattta aagctactac agcttctcta
    34561 acgcaagatt ttagtttatt aatatcaaat gtagcatgtt caccaaatgg ttgtattata
    34621 aactctgata agtttattga gccaagtaga caactacctc cacttggaag tggctcttct
    34681 gcacaaggat ttactcctga aaagcaaaag ttcttatctt cactcataag attatatgtt
    34741 tttattttat cccagaataa tatacctggt tctgcataat cccagttatt tttcacaaat
    34801 ttattaaata aatcatacgc atttactatc ttaactattt tttctccagt agtttcaact
    34861 tcaaaagtac aattatataa ctttttttcc cttacagctt gcataaattc atctgttact
    34921 cttacagaaa tatttgcttt agtaaccttc tccaaatctg tttttatatc tataaactct
    34981 tctatctctg gatgatttac atccatagaa atcataagag ctcctcttct ccctctttga
    35041 ccaattaagc cagttgtcat actataaagt tccataaaag agactgctcc agtcgtatgt
    35101 tttgcagcat tgttaacttt cgctcctttt ggtcttagct ttgaaatgtc aattccaact
    35161 cctccaccat aactaaaagt tctagcaagt ttttttgcag tatcgaaaat atcttctatg
    35221 ctatcttttg gtggttctat tacataacaa ttggaatatg ttactttttt tccttctttc
    35281 tgtaatcctc tatttgctaa aattcttcca gcaaatagaa atcttttttg tcttattagt
    35341 tttgatattc ttgaactatt atttgaaatt ctctttatcc attcatcaaa actctcacca
    35401 ttatgtctat acttgttctt ccatattgat ttttgtaatt catcaaactc ccaagcttta
    35461 gttcttattt ctgagcgtct ttctctatat aatatgtagt gttttgctat atcttttcta
    35521 tttgattcca taagtagtac ttcaactata tcttgtattt cttctacgga taagcatttt
    35581 tccatagaat tatagtcatt ggctattttt cttgatatat catatgccaa atctctatct
    35641 actccacctt cactatttat actagcttta tagacagcat cttcaatctt acttttgcta
    35701 aaaagttctt ttgtaccatc tctttttatt atgtacttca tttttagacc tccaataaat
    35761 tagtattaaa ttaatacaca cattaactat aactctaaac aaacttttta tatatttgta
    35821 tattttcata ttaattatct aacataatat atattatact attttatatt caatataaca
    35881 ctccttatag ttttctcaac ttgtaaaata tcttcctaaa aaactcaaaa ataatataaa
    35941 aaagtatata aaagtctaat tatactctta tatactttat tttttt
//
LOCUS       DBGJFK010000036        35804 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.036, whole genome shotgun sequence.
ACCESSION   DBGJFK010000036 DBGJFK010000000
VERSION     DBGJFK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.036"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..1325
                     /locus_tag="ACOIAP_002049"
     CDS             <1..1325
                     /locus_tag="ACOIAP_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2638932.1"
                     /translation="VGIYLFFMSVSDFIMLKIKKHRFIYYKNLNPFIVSQISSQIKTM
                     SMSITMICMLLFSSLIVIPFGISFGKYLIDDLQEATPYDVTLSKLYMNGDNIVEYSTK
                     KNDIDSKTPSLKDELIENGFPLTSFSKSTSDLRIYNLKNISQYDFISNDKDRTNELKD
                     NKLHIVSISDYNFTRKQSGLKEINLKDNEFAINCASEDYRPFYEKYIKSQPQNYITVN
                     GVKLKLNQTSLYTNSYNTNTVPLDLGTIIVPDAVVKDLNPIMTTLNIDYKERSSNLEN
                     KFMDSYYKFEEKINNSEAYSILYKSVIDGEKRALNTSFSFVAIYIGIILLISAGAILA
                     LQQLIESTVNKERFKLLSKLGVNKKDMKKAIFIQVSILFAVPLILALINALFISKVFF
                     VIMPFIAETGIITTMLLTLGIVIVVYGIYFISSLLESLNIVNDSKEII"
     gene            1542..2753
                     /locus_tag="ACOIAP_002050"
     CDS             1542..2753
                     /locus_tag="ACOIAP_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2638933.1"
                     /translation="MQIKIGKIIQALRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVTKIYKELESIFAGIEVDLSTEEPKEEC
                     KRDLEYVKNLSNMYIEKYPKSYLLKLKICSLYQMYSYKFGKNDFNNNVRETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKPIGDTSVNLAMIYLNQNKL
                     EEAEILLQNKLFSNVFNLSLDCKGIINVYKYQYKELKKKLEYGDSNKKAIEKEMEYIK
                     NKLLGYANLSLEIKKMISEDKGAFFGIYMDYMELSLTFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVKSKNSYTFNMYTNLLIMFSDDSYNELRGEPIFESIIEK
                     ILELEKLLKDK"
     gene            complement(3064..3585)
                     /locus_tag="ACOIAP_002051"
     CDS             complement(3064..3585)
                     /locus_tag="ACOIAP_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HGZ2638934.1"
                     /translation="MKFERLRTSKDKLYYKAMELYKTSFPFHEQRKSSLQAKIMENKE
                     YQFNLIYDKNQFVGIILCWETKSFIYVEHFCIFPEMRNNRYGQKTLELLNKRGKTIIL
                     EIDPPIDELSTRRKKFYERVKYKTNYYKHIHPPYQEKFNGHQLVVMSYPERLSKMEYD
                     KFNQYLKNHVMNF"
     gene            3947..4744
                     /locus_tag="ACOIAP_002052"
     CDS             3947..4744
                     /locus_tag="ACOIAP_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGZ2638935.1"
                     /translation="MEKREKRIIISSLLSVSILMSLVSIYSILNKEDISLTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGKEGEKKLIYNLTYHDEKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGSKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            4854..5444
                     /locus_tag="ACOIAP_002053"
     CDS             4854..5444
                     /locus_tag="ACOIAP_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGZ2638936.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLVRFNEDVVKNSPDIVFIMGGTNDFIAGAGNEVINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNIREDWSCFTDFNIVSQKLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            5509..7206
                     /locus_tag="ACOIAP_002054"
     CDS             5509..7206
                     /locus_tag="ACOIAP_002054"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGZ2638937.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKIELEKIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETNRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSIIPTPSEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNIPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTIGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYEGLIELYEK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSVKVIDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVGKLK"
     gene            7407..8246
                     /locus_tag="ACOIAP_002055"
     CDS             7407..8246
                     /locus_tag="ACOIAP_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGZ2638938.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLIGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIKHE
                     MLK"
     gene            8765..10621
                     /locus_tag="ACOIAP_002056"
     CDS             8765..10621
                     /locus_tag="ACOIAP_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2638939.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYQVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIVGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGESTGKLFKDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIIDNIIYSGYSNKNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVESKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTAKDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKIQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKEDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGVGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    10704..10944
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    11010..11245
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11330..12547
                     /locus_tag="ACOIAP_002057"
     CDS             11330..12547
                     /locus_tag="ACOIAP_002057"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGZ2638940.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKGKKYSNMITNNIDDIFNKDIDILVEVMGGLEPALSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            12663..13157
                     /gene="cdeM"
                     /locus_tag="ACOIAP_002058"
     CDS             12663..13157
                     /gene="cdeM"
                     /locus_tag="ACOIAP_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HGZ2638941.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGGSDSEGNRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     QAEKYWDEYSKYNYQGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            13396..14661
                     /gene="hisD"
                     /locus_tag="ACOIAP_002059"
     CDS             13396..14661
                     /gene="hisD"
                     /locus_tag="ACOIAP_002059"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HGZ2638942.1"
                     /translation="MKRIKTSSMKEKVDEKILREQVSSIIEDIRNNKDIALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIKEFAKAQKSSFENSFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKIKPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSKPVYIAADLLAQCEHDLNARGILLTNSLEIAEEVEKNI
                     ETMLKDLPTKDIAYSSWKNNGEIILVDDMEEAIKISNFYAPEHLEIAVNKCDDIFDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEEAI
                     ESLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(14866..15618)
                     /locus_tag="ACOIAP_002060"
     CDS             complement(14866..15618)
                     /locus_tag="ACOIAP_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2638943.1"
                     /translation="MSYFQYQGNACFYEEYGQGKPIVFLHGNTASSNMFKALMPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDMWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCQGKDWEN
                     VVNLDTKALLQCAKEKRPLFHKELCKLEMPILFIGSKEDEMCRHNLEEEYKQMATFIR
                     KASIHIFSHGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(15817..16005)
                     /locus_tag="ACOIAP_002061"
     CDS             complement(15817..16005)
                     /locus_tag="ACOIAP_002061"
                     /inference="COORDINATES: protein motif:HMM:NF040785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3324 family protein"
                     /protein_id="HGZ2638944.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQK"
     gene            16480..16836
                     /locus_tag="ACOIAP_002062"
     CDS             16480..16836
                     /locus_tag="ACOIAP_002062"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638945.1"
                     /translation="MKNIVGKSQTIKKVNEDLIKNIIKNEGPITKLEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNYCIGVVANLL
                     GEIIYQEKFNIRMDTY"
     gene            16946..17305
                     /locus_tag="ACOIAP_002063"
     CDS             16946..17305
                     /locus_tag="ACOIAP_002063"
                     /inference="COORDINATES: protein motif:HMM:NF012692.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGZ2638946.1"
                     /translation="MVKNIPTIKSWEGINLENLIKSKYNTKLFIENDTNITTIGIYQK
                     QYKEKYKNMALMYLENGIGSGIVINDELYLGSTNFAGELNYLNIEFGKYNSNNLNLEE
                     YMYLVYLVVILLMTIRL"
     gene            17305..17460
                     /locus_tag="ACOIAP_002064"
     CDS             17305..17460
                     /locus_tag="ACOIAP_002064"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638947.1"
                     /translation="MDEILKIGINKEKIYLENDAVLAFYAQADSHGLVIVAGTGSIIL
                     GIKEDGG"
     gene            17860..18492
                     /locus_tag="ACOIAP_002065"
     CDS             17860..18492
                     /locus_tag="ACOIAP_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2638948.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            18918..18995
                     /gene="kdpF"
                     /locus_tag="ACOIAP_002066"
     CDS             18918..18995
                     /gene="kdpF"
                     /locus_tag="ACOIAP_002066"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA];
                     GO_process: GO:0043462 - regulation of ATP-dependent
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HGZ2638949.1"
                     /translation="MWFLAVVIIMLIIYLVYALINPEKF"
     gene            19042..20718
                     /gene="kdpA"
                     /locus_tag="ACOIAP_002067"
     CDS             19042..20718
                     /gene="kdpA"
                     /locus_tag="ACOIAP_002067"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HGZ2638950.1"
                     /translation="MVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFI
                     YKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGLSF
                     NTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYSAAMAFVRGLVGKKKT
                     LGNFYVDLIRITTRVLLPGALIIGIILVTQGVPQTFAGTETVTTIEGKLQDIARGPVA
                     ALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGYMIKNKK
                     QGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSSLF
                     TAVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLC
                     GLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAVPAGLEGISNPGFHG
                     LSQVLYEFSSSAANNGSGFEGLGDNTMFWNMTTGIVMFFGRYVSIIVLLAISSLLASK
                     KAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            20743..22800
                     /gene="kdpB"
                     /locus_tag="ACOIAP_002068"
     CDS             20743..22800
                     /gene="kdpB"
                     /locus_tag="ACOIAP_002068"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HGZ2638951.1"
                     /translation="MDTKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRVYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFITVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGIVPEDLEENVNRVAKLGGTPLVVCVDNGIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQSE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            22819..23445
                     /locus_tag="ACOIAP_002069"
     CDS             22819..23445
                     /locus_tag="ACOIAP_002069"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HGZ2638952.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELRDRVQKDIEQFLKDNPTVKKEDIPTDLLTASGSGLDPNISPDSAKIQIPAV
                     AKASGISESKLQKIVDDNTSKKVFGVLGEDRVNVLKVNVEVARILGLI"
     gene            23682..24590
                     /gene="cysK"
                     /locus_tag="ACOIAP_002070"
     CDS             23682..24590
                     /gene="cysK"
                     /locus_tag="ACOIAP_002070"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGZ2638953.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEKRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSIER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIKVVALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEIILVDDEDAFDTVKLLASKEGILVGISSGANIFGAIEM
                     AKRYPDKKIVTVAPDGVDKYMSMGIF"
     gene            24617..25207
                     /gene="epsC"
                     /locus_tag="ACOIAP_002071"
     CDS             24617..25207
                     /gene="epsC"
                     /locus_tag="ACOIAP_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HGZ2638954.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVDYEYDELDNVYYI"
     gene            25368..25556
                     /locus_tag="ACOIAP_002072"
     CDS             25368..25556
                     /locus_tag="ACOIAP_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGZ2638955.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMNDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(25610..26479)
                     /locus_tag="ACOIAP_002073"
     CDS             complement(25610..26479)
                     /locus_tag="ACOIAP_002073"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGZ2638956.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEVGISTEDINKLVHEFTLQNGAIPAPLGYNG
                     FPKSVCTSINNEVCHGIPNKDIILKDGDIINVDVSTIFNGYYSDASRMFMVGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAVNSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(26676..27920)
                     /locus_tag="ACOIAP_002074"
     CDS             complement(26676..27920)
                     /locus_tag="ACOIAP_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638957.1"
                     /translation="MENNLNTAKRNNTELSQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEEANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTNGLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILNLEDIHSYSMENNTNITIYENDNLQYKFDEESEDIKDSNI
                     DIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQALKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYTNVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMKVFAQERYKLYDPKQIAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELYY"
     gene            28213..28515
                     /locus_tag="ACOIAP_002075"
     CDS             28213..28515
                     /locus_tag="ACOIAP_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGZ2638958.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGVNSKYTRAKGFK
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPNILINSINNKTDYIIGKEIE"
     regulatory      28617..28709
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            28809..29603
                     /gene="thiD"
                     /locus_tag="ACOIAP_002076"
     CDS             28809..29603
                     /gene="thiD"
                     /locus_tag="ACOIAP_002076"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGZ2638959.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTQGVFAVEDLNKNIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVKNLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGKEILQLGPKFVLMKGGHLDGEAVDILIGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNFSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            29627..30412
                     /gene="thiM"
                     /locus_tag="ACOIAP_002077"
     CDS             29627..30412
                     /gene="thiM"
                     /locus_tag="ACOIAP_002077"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGZ2638960.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANATLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEDSTDIIRKVAKKLECIVVA
                     TGKIDIITNGKSTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLTM
                     SLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            30435..31067
                     /gene="thiE"
                     /locus_tag="ACOIAP_002078"
     CDS             30435..31067
                     /gene="thiE"
                     /locus_tag="ACOIAP_002078"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGZ2638961.1"
                     /translation="MIDKESLKKCLRLYLITDSEMLEGRDFYKCIEDAISSGITTVQL
                     REKNTCGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNDKILGVSARTLEEAICAKNDGADYLGIGSIFSTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLDSDGYAIISAILKAEDISKEVEKWTLKI"
     gene            31206..31508
                     /locus_tag="ACOIAP_002079"
     CDS             31206..31508
                     /locus_tag="ACOIAP_002079"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2638962.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMFDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(31574..32323)
                     /locus_tag="ACOIAP_002080"
     CDS             complement(31574..32323)
                     /locus_tag="ACOIAP_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638963.1"
                     /translation="MLNILWRSMKWRFKNPISFIVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIILVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVAILCIVSIFFSVTIESGIGGILLMTVLVFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIENLSGGLKVVVMLNPFTHVINALRSLIFGETVLI
                     EDILPVILLFLILCCASFSLAMWRLKKEMVS"
     gene            complement(32317..33279)
                     /locus_tag="ACOIAP_002081"
     CDS             complement(32317..33279)
                     /locus_tag="ACOIAP_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2638964.1"
                     /translation="MLAVEIDNLVKEYKNGVKALNGLSFNVNSGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMIFQS
                     KMYKVKPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRYEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNIIRITFHNTEDIKKYNDAIKGTGLVKFMNVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEGWEC"
     gene            complement(33283..33735)
                     /locus_tag="ACOIAP_002082"
     CDS             complement(33283..33735)
                     /locus_tag="ACOIAP_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGZ2638965.1"
                     /translation="MSYKIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNGAP
                     FFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHIGSYSNLPKTYE
                     MIFKYIHENNIKIQTPWREVFIKGPGMLVKGKPDNYITEIIFPLKEEE"
     gene            34096..34452
                     /locus_tag="ACOIAP_002083"
     CDS             34096..34452
                     /locus_tag="ACOIAP_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2638966.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVIGELKPGDTIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNHQSSVTIDENILKNLKLELINESLSVFLKDMKA
                     INVTKEEVLKIIEDKY"
     gene            34524..35240
                     /locus_tag="ACOIAP_002084"
     CDS             34524..35240
                     /locus_tag="ACOIAP_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2638967.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINTDSGEIRIDGEKINEKIYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKKKSKEMMNIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVIILDEGQIIASFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            35233..>35804
                     /locus_tag="ACOIAP_002085"
     CDS             35233..>35804
                     /locus_tag="ACOIAP_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2638968.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLGLNLFEINKFKNS
                     KFIINLAIGDFGGIFYGIGILSNLGFIQSILFFGMLGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALLTMIYGFLISQIATLFICKYIFNFIFRNVPIINMNFAK
                     DLYYLNLKGIPIDFISFMAIYVFLLLIAIS"
BASE COUNT        13907 a         3955 c         6018 g        11924 t
ORIGIN      
        1 tagttggaat ttatttgttt tttatgtcag tatctgattt tataatgtta aaaataaaga
       61 agcatagatt tatatactat aaaaatttaa atccatttat agtaagccaa ataagtagtc
      121 aaatcaaaac aatgagtatg tctattacta tgatttgtat gttattattt tcttctttga
      181 tagtaatacc atttggtata tcatttggaa aatatttaat agatgattta caagaagcga
      241 cgccttatga tgtaacatta tctaaattgt atatgaatgg agataacatt gtagaataca
      301 gtacaaagaa aaatgatata gatagtaaaa ctccttcact taaagatgaa ctaatagaaa
      361 atggttttcc actaacttca ttttctaaaa gtacaagtga tttaaggata tataatttaa
      421 agaacataag tcagtacgat tttatatcaa atgataagga taggacaaat gaactgaaag
      481 ataataaact tcatattgtc tcaattagtg attataattt tactagaaag caaagtggtt
      541 taaaagaaat aaatctaaag gataatgagt ttgcaataaa ttgtgcctca gaagattata
      601 gaccatttta tgaaaagtac attaagagtc agccacagaa ttatataaca gtaaatggag
      661 taaaacttaa attaaatcag acaagcttat ataccaattc ttataatact aatacagttc
      721 ctttagattt gggaactata attgttccag atgctgtagt aaaggattta aatcctatta
      781 tgactacatt aaatattgat tacaaagaaa gaagtagtaa tcttgaaaat aaatttatgg
      841 attcatacta taaatttgaa gagaaaatca ataattctga agcttatagt attttatata
      901 aatcagttat agatggcgaa aaaagagcct taaacacttc attttctttt gtagcaatat
      961 atataggtat tatattatta atatcagcag gtgcaatatt agcattacaa caactcatag
     1021 aatcaactgt taataaagaa agatttaaat tattaagtaa gcttggagta aataagaaag
     1081 atatgaaaaa agctattttt atacaggtat caatattatt tgcagtacct ttaatattgg
     1141 ctcttataaa tgctctgttt atatcaaaag tattcttcgt tataatgcca tttattgcag
     1201 agacaggtat tattacaact atgttattaa cattaggtat tgttatcgtt gtatatggaa
     1261 tttattttat ttcaagttta cttgaaagtc taaatatagt aaatgatagt aaagagataa
     1321 tctaagtctt taaaaagact atttattgtg aatctattaa ttaagttaca cttaagttag
     1381 cttagttaat agattttata ttttaattca atgaaagaat cttttagact aaaatataac
     1441 caatagttaa attatgaata ttttattaac tttgactcaa tttacttgta agtacttttt
     1501 ttatatactt aaattacaat agttatgcta gggaggtata tatgcaaatt aaaataggta
     1561 aaatcataca agctcttaga aaagaaagaa atctaactca agagcaattg gcaaaattta
     1621 taggagtatc aacaccagca gtatccaaat gggagagtgg aaattcttat ccagatatag
     1681 aattattgcc attattggca gattttttta atgtatctat tgataagctt ttaaactaca
     1741 agattgattt aagtgaagaa gaagtgacga aaatttataa agaattagaa tcaatttttg
     1801 cgggaattga agttgattta tcaacagagg aaccaaaaga agaatgtaag cgagacttgg
     1861 aatatgtaaa aaacctttct aatatgtata tagaaaagta tcctaaaagt tatctattaa
     1921 agttaaaaat atgttcgttg tatcagatgt attcatataa atttggcaag aatgatttta
     1981 ataataacgt aagagaaaca acaaatatac ttgaagatat agtaagaaat acagatgata
     2041 ttcaaataaa agaaacagca ctcattatct tatcaaatgc atattgtatg ttggaggatt
     2101 atgaaaaggc agagctgtac ttaaatatga tacataaacc aataggagat acaagtgtca
     2161 atttagctat gatatattta aatcaaaata agctagaaga agcagaaata ttgcttcaaa
     2221 ataaactgtt tagtaatgta ttcaatttaa gtttggattg taaaggaata atcaatgtat
     2281 ataaatatca atataaggaa ttaaagaaaa aattggagta tggagattct aataaaaaag
     2341 caatagagaa agaaatggaa tatataaaaa ataagttgct agggtatgca aacctctctt
     2401 tagaaattaa aaaaatgatt agtgaagata aaggtgcatt ttttggtata tatatggatt
     2461 atatggaatt atctttaact tttttatttt tcaatatgaa agaagaagcc aaaaaagctt
     2521 tatatagtct aaaagaaata ttagaaaaat accctataca tgaaagtttg gatgttagtc
     2581 agatgagatt ttttgacaaa gtaaaatcta aaaattcata taccttcaat atgtatacga
     2641 atttattaat aatgtttagt gatgatagct ataatgaact tagaggagaa ccaattttcg
     2701 agtctataat tgaaaagatt ttggagttgg aaaaattatt aaaagataaa taataaataa
     2761 aaatctaata taagatttaa agattaatta aattaaaagg agatgtgtca aaacacaaat
     2821 ttgaaccatc tcctttatta cataaaaaaa atagaaaagg gcttgttaag aagtattcta
     2881 aaaccattaa atcaaatgat tatatcaaaa gaatagaaat atattaaaaa taaacaaatg
     2941 aaaattaaga agctgatata ttttcatcat tttaacaaaa aagagaccta tctctatttt
     3001 gagacagcct cttttatgta attgttatga aactttgcac aactcaatag ataggaacta
     3061 tacttagaag ttcattacat gattctttaa atactgatta aatttatcat attccatttt
     3121 agataatctt tctggataag acattacaac tagttgatga ccattaaatt tctcttggta
     3181 tggtggatga atatgtttat aataatttgt cttatatttt actctctcat agaatttctt
     3241 gcgacgagtt gaaagctcat caattggagg gtcaatttct aaaataatag tttttcctct
     3301 cttatttagc agttctaacg ttttttgtcc atatctatta ttacgcattt ctggaaaaat
     3361 acagaaatgt tctacataaa taaagctttt tgtttcccaa catagaatta tgccaacaaa
     3421 ctgattttta tcataaatta aattaaattg atattcttta ttttccataa tttttgcttg
     3481 caaagaagat tttctttgtt catgaaatgg aaaactagtt ttatataatt ccatagcttt
     3541 atagtataat ttatctttgc tagttcttaa ccgctcaaat ttcattttgt tcctcctaat
     3601 tacgaaaaat tccgatttat atatgaattt attttatcac agtcagcatt tgtatacaat
     3661 gtgttttcag ttgtatatta tttctcaatt ttattccact tatgtctaca tctcatgggc
     3721 tgaaatataa ttgtttattg tgtaacctca aactattata caggttctga tggcttaaaa
     3781 acagcatact tatagaattt ttttatgtat gaaaatgatt ttaatagttt tagaagttac
     3841 aaaaaagtta cataaatttg gaaagctata atatacatat ataatataag gttaaaactg
     3901 taataaataa tgttaattta aaatttgaac atggaaggag attattatgg agaaaagaga
     3961 aaagaggata ataatatcat ctttattaag tgtatcaatt ttaatgagtt tggtaagtat
     4021 atattctata ttaaataaag aagacataag tttaactgtt aaaggtcaag agcaaaaagt
     4081 atcttccttt aagaaaacag ttgaagaact tttggatgaa cagggtgtaa agtataattc
     4141 tgaagataag attaatccaa gtttagatac agagctaaaa gatgatatga aaataaaagt
     4201 tgttaaggta actaaaagta aaaaagaaga aattgaaaaa attccgtttg atacaaagca
     4261 tgtaaatgat agtaatttgt taaaaggaaa atctaaagtt tatcaagagg gtaaagaggg
     4321 agaaaaaaaa ctaatctata atttaactta ccatgatgaa aagttagtca aaaaagtctt
     4381 atcaaaagaa gtaatatcta aggagccaac tacaaaaatt ataaaatatg gaactaaaga
     4441 aaaagtacta atagcatcaa gaggagcaaa tataagagga agtaaacata tgaaagtggt
     4501 tgctactgca tatgcaggag atacaataac atctactggt acaactccaa gatggggtgt
     4561 tattgcagtt gatccacgtg taataccata tggaacaaaa gtatatatac ctaagttagg
     4621 tatgactttt gtggcagaag attgtggagg tgcaattaaa ggtaatagaa tagatatttt
     4681 tatgaatagt gaaggaaaag cctcaaattg gggaaggaaa agcatagata tatatttaca
     4741 ttaaattagt gaatagaata actttacttg aaagataaaa aagtataaaa tatgaattaa
     4801 ctaaactatt agattattct taaaacataa aaatatatct aaggggggat aagatgaaaa
     4861 tagtctgttt aggagacagt ttaacatatg gatttggagt atcacgaagt aattcatgga
     4921 caaacattgt aaataaagag actcgattag aaatagtaaa taagggtata aatggtgata
     4981 caacaagtgg tatgttagtt aggttcaatg aagatgttgt aaaaaactct cctgatatag
     5041 tttttataat gggtggtacc aatgatttta ttgcgggtgc aggaaatgaa gttattaatt
     5101 ctaatataat ggctatggta catcagtcat attcaaaaaa tattatacct ataataggta
     5161 taccattaaa accagatatt ccaaatatta gggaagattg gagttgtttt actgatttca
     5221 atatagtatc tcaaaagtta gaatcatata gctattggat aaaaaaattc tgtatgacat
     5281 ttaatactaa tttcgtagat ttttattcag aatataataa aaatatggaa ctagaaggat
     5341 ataaaaaatt atattttgat gggttacatc caactaagga aggtcataga ataatggcag
     5401 acatttttat taattcaatt aataagtata tagaagagtt atagttacat caaaatactt
     5461 gtttatgtgt cagtttcaat aaatacatac agtagagagg ggtttattat ggattatact
     5521 aaaacttatg aagagtggat aaagggttca tattttgatg aagatacaaa gatagagttg
     5581 gagaaaataa aaaataatga aaaagagata gaggatagat tctataagga tttagaattt
     5641 ggaactgcgg gtcttagagg aataattgaa gcaggaacga atagaataaa taagtacaca
     5701 gttagaagag ctacttttgg attggcaaac tatatattag aaaacacaac aaaagaagaa
     5761 acaaatagag gagtagtaat agctcatgac aatagacaca agtctagaca attctgtata
     5821 gaatctgcaa atactttggc agcatgtggt ataaaagcat atatatttga tagtttgaga
     5881 actactccag aattatcttt tgctgttaga agcttaaatg caatcgctgg tatagtcata
     5941 acagcaagtc ataatcctcc agaatataat ggatataagg tatactggga agatggagca
     6001 caagttatgc cagagattgc aaatgcaata acagagaaag taaatagtat acatgattat
     6061 agtataatac caaccccaag tgaagctaat aaaaatttag tagttttatt ggatgaatca
     6121 caagatacta aatttataga agcagtaaaa agtcaaatta taagaaaaga tttagttaaa
     6181 aatgtaggta aaagcttcaa gatagtttat acacctcttt gtggaaccgg aaatattcca
     6241 ataagaagag cattaaaaga agtgggtttt gaaaatataa ttgtagttcc agaggaagaa
     6301 aatccagacc caaattttgc agggcttgat tatccaaatc cagaagagaa aaaagcttta
     6361 aatagaggta tattactcgc aaaagaaaaa ggagcagacc ttgtaatagc aactgaccca
     6421 gattgtgata gagtaggtgt agcagtaaaa actactatag gtgagtatgc tttacttaca
     6481 ggaaatcaaa ttggtggtat gctaacacat tatataatag aaggattaaa agaaaataat
     6541 aaattaaaag aaaatcctac aataataaaa accatagtta cttcagaatt tggagcagat
     6601 atagctaaag caaataatgt tgatgtatta aatgttctta caggttttaa atttattggt
     6661 gaaaaaataa aattatttga acaaaataaa aatagaagtt atgtatttgg atatgaagaa
     6721 agttatggtt acttagttgg tactcatgcg agagataaag atggtgtagt ttcttcgtta
     6781 ttaatatctg aaatggcagc cttttactat tcaaaaggta tgagtttata tgaaggttta
     6841 atagaacttt atgaaaaata tggatttttt aaagaacaga ccatatcctt gactttaaaa
     6901 ggtatagaag gtgtagaaaa gataaaagaa ataatatctt actttaggga aaatcaaatt
     6961 gattatataa atagtgttaa agtcattgat aaaaaagatt ataaaaatgg tatagataat
     7021 cttcctaaat ctgatgtttt aaaatacttt ttggaagatg aatcttgggt agctataaga
     7081 ccatctggaa cagaaccaaa acttaaattt tacatagctg taaaaggagc tagtgatatt
     7141 gaagcagata aaaagattca aggtttaaaa aaatatatag atgacatggt cggaaaatta
     7201 aaataaaata ttattatttt ataataatat ttatttagct gaaaattata atttactttc
     7261 attgattaga atatgtaaat gttagtagaa ttgttatttt cagcttttat ttgtgttatt
     7321 tttacttaaa taattatatt atagtatgaa tctgagtata attaatattg tataatgaaa
     7381 ttaatttgat agaaaagggg atatttatgt ttggtataga taagaaattg attgaatata
     7441 taattgcaaa atccaattac agtgaactaa gttcaaagtc agcagaagta tctttcttct
     7501 taatgttgtc catatttcct tttttgatat ttacaataag ttctatcgct tatataccaa
     7561 ttcttcattt aaataagtat atagctttgt ttagaaatat gatgccagaa ggagcttttg
     7621 ccgtattatc ttcaatcata gtttctgcaa tagacaatag aaatctgaaa tttttagcgg
     7681 tcagttttgt tcttactatg tggacatttt caagagcagt aaaagccctt attaaaggaa
     7741 tgaatagagc ttataaagtt aaagaaacta ggtctttttt taaaatttta tctatatcat
     7801 ttttatttac aataatgctt ttggttctta tttttttatc tatgatattt ctagtttatg
     7861 gggaaaaaat aggttatttt atttttaatc tcataggact agatgagata tttataaaaa
     7921 tatgggatat tctaagatac actgtaggta taataacaat aatagtgata tttacacttt
     7981 tatataaata cactccaaat aaaaagctaa ctattaaaga atctgcacca ggtgctattt
     8041 ttgctacttt tgcttggttt ttagtatcat ttttatattc ttattataca aattactatg
     8101 ctaactatga agtaatctac ggaagtatag ctgaaataat tgtacttatg acctggatgt
     8161 attttagtag ttggtctatc gttattggtt atgaagtaaa ttcaagattg tattttagaa
     8221 agataaaaca tgaaatgtta aagtaaagca ttaaaataaa ggatattatt taatattata
     8281 aatgtaattg aattaataaa aaatattgac atttaagtta aaaagtctag aatttttctg
     8341 ggcttttttt atttttagta caacttgaca aactttattt aatgggatag ttttaattta
     8401 taatcatctt tgaaaagatg actattgata agcaagagat gaaattggta aaagtataaa
     8461 aaaatatact aaataaagat tatagtccta atgagttaat gtctgtgttt tcaaataatg
     8521 cagtatttag tcatgtgttt ttatatgcgc ctgtattcct aattaccaat atatattaga
     8581 ataagctact gtaattagat ttagaaaaaa gcgacataaa taattataaa caaataataa
     8641 attacataaa attaaattta ttcacaagta tatcttataa aatatgttat aattaataga
     8701 aaattgtcat ataattactt aagaagtatt attataaata acattgagag gtagtggtta
     8761 gaatatggat acccataata aatatgtaaa ttttataaaa aatatacctg tacctttttt
     8821 atattgtaga attgtaaaga gacaagaaga tatagaatat caagtagagt atataagtaa
     8881 gggtatgggc aaagtattac aattagaaga aggtatttgt gataaaaata tattagatgt
     8941 attgcctgta tttaaatcta aaaaatattt caaagagttg ttctcaaatg aagtggattg
     9001 tataaaaagg tacattccaa cacttaaaaa ctggataaat ataaaaaaac agatagtagg
     9061 ggattcatac ataattttgt attttggtaa aattgtattt gattatagac agataatcga
     9121 ttcttttgat aaaaaggaaa aagtagctta tattaaagat gaagaaggca tatatataga
     9181 ttgcagtgaa aatttaatac caatattaaa taataacatt aaaacaacaa aagatatctt
     9241 tggtaaaaat gatatagaag tatggggaga gagtacagga aaattattta aagatgatta
     9301 tagagaaggc gtatctagca aaaaaagatt tttacaaaat ctttttgaat atgaagaaac
     9361 atttttcatg gttgaaaaat attttttgta tgacgaagat gaacttttag gtactatagg
     9421 gataatagac aatataatat atagtggtta cagtaataaa aattataact caaaagactt
     9481 aatgaagatg atagagcact caattccaga gaatatgttt tataaagatg tgtatggaaa
     9541 ttatattgga tttaattcag gttttttaaa tttagcttgt atgaataaag aagaattatt
     9601 aggaaagaat agttataaaa tatcagaaga agaagcttta atagataaga tatttgaaag
     9661 tgataagggt gtagttgaaa gtaaaaaagt agttacattt gagttaaata taagtatgaa
     9721 tgatgaaaac aagtgtattg agattacaaa aaggccattt tttgatagct atggaagtgt
     9781 tattggaata attggaacag caaaggatat aagtagaaga aaaagattag aagaggaaat
     9841 ggataaaact aggatggaat tttttgcaaa tttatcccat gaacttagaa cacctataaa
     9901 tttaatatca tcttcattac aagtgataga aaaaaaagaa gcagacttaa tagaatcaaa
     9961 tgatacttta aaaagaaatc taggcataat aaaacaaaat ggaaatagaa tacttaggtt
    10021 agtaaataat gttatagact ttacaaaaat tcagtcagga tatttagatt ttaaaccaga
    10081 agaatctgat ataattgcat ttatagaaga gatatgtatg tctgtagccg actttgcaag
    10141 tcaaaataat atacaactta catttgatac agaaatagaa gaattttcaa tgctatttga
    10201 ttcagaaaaa ttggaaagaa taatattaaa tttactttct aacggaatta agtataataa
    10261 ggaagatgga aaaataaaca tatttttata tgtgaaggat aatgtattta atatgaaaat
    10321 atctgatagt ggtataggta taccaaaaga aaaaatagat aaaatattta ataggtttga
    10381 acagattgac aatgaacttt cctacagagt taaaggaagt ggtattggac tttcattagt
    10441 gaaatctttg gttgagttgc atgagggaag tatatcttta aaaagtcaac ttggtgttgg
    10501 aagtgaattt atagtttcat tacctgttag aagtaaaaat aatattgaaa aatacaatca
    10561 taaaagagaa atcagtaatg aactaagtaa aaaattagaa atagaatttt cggatttata
    10621 agtttaagta taaaaaataa aattttaaaa aagtattgac aattgattta gaagggttta
    10681 aaataaatta caacataata aataaaaaag cgatgaatag gaagagtaaa tctaattcga
    10741 ttgccagaga gaagagtcca ttggctggaa gactttttaa attagaggga ttgaaaacta
    10801 cctaggagct actttctgaa gttatctaca tcagtagatt ttagtaagaa tagtcgttaa
    10861 ctgcgttaaa gtgtaaagtg agttttcatg atatatgaaa actaaattag gtggaaccgc
    10921 gggaataata ctctcgtcct tatgttataa ggatgagagt tttttgttat ttaaaaatat
    10981 aaacagtaat cataataatt atagaaaata taaaagcgat gaataggaag agtaaattta
    11041 attcgactat cagagaggaa agttcgcagg ctgaaagact ttctaagttt gagaaattga
    11101 aaactaccta ggagctgtgg tctgaagtta ctttaaaaag ttttagtaag actaaccgtt
    11161 aactgcgtta aagtgtaaag tggattttat caattaatga taaaatcaaa ttgggtggaa
    11221 ccgcgagtat agactcgtcc ctttatatag ggatgagtct atttttagtg caataaaaga
    11281 gtgaaaataa aaaaaaatcg gaaaattata aatttaggag gaaaataaaa tggagaataa
    11341 agtgaaaatt ggagtactag gatatggagt tgtaggaagt ggacttatag atataataga
    11401 taacaataaa gaaaaaagaa acatagaaat agttgggatt ctagttaata atttggaaaa
    11461 acataagggt aaaaaatatt ctaatatgat aactaataat atagatgata tatttaataa
    11521 agatatagat atacttgttg aagttatggg tggtttagaa ccagcattat cttatataaa
    11581 aaaagcatta aacaataaaa ttcatgttgt tacagcaaat aaagatttgt tggctgaatg
    11641 tggagatgag cttgcaaaat tagcaagtga aaataaagta agcattaaat ttgaagcttc
    11701 agttgcagga ggtataccag tattaaaacc aataatagaa tcactagaag gaaataatat
    11761 agatagtata aatgcaattt taaatggaac tactaatttc atattatcta aaatgtatga
    11821 tgagaatcta tcttatgata tggcgttaag acaagctcaa gaattaggtt ttgctgaagc
    11881 aaatccagag tcagatgtat tagggtatga tgctgctaga aaactatcaa tattatcaac
    11941 tctagcttat gacaatagag tatattggaa agatgtgtat ttagaaggaa ttacagatat
    12001 agatgaaaaa gatattgaat acgcaaaaaa attaaattgt aaaataaaat tgattggtca
    12061 aagtaagtat gaaaatgata aagtaagtgc ttttgttaga cctgttttag tagaaaaaga
    12121 taatatactt gctagaatag acaatgagtt caatgctgtc atagtgaatg gagattcagt
    12181 aggagaagtt tcttttgtag gtaaaggagc tggaagttta gcaacaggaa gtgcagttta
    12241 ctcagatgtt atagatataa tagataatag agtttcaagt atagattctt ttactaaaga
    12301 taaaatacaa gttaataaaa tagttagaga aaagtgtgga gcacttctta gatttaaaaa
    12361 atgtaataaa gatgaaattt taaatatagt tgagaattgt ttagttaaat ttgatatttt
    12421 aaatgatgat gatgaacttg ctattatggt ttatgctgat tctgaatatg aaataaataa
    12481 cagtttatgt ctaataaaag ataaaggata ttgcgaaaaa atgaataaaa tgttgaaaat
    12541 aagttaaaaa agaaaaaata taagtttata tgtaacatat tttgacgatt ttaatactat
    12601 atagtatgag atgaaacaaa acatctcata aaaaaattaa aattaaaggg gagatatgtt
    12661 atatggaaaa taaaaaatat gcaaatggtg gttattcaga agattggtat gaaagaggag
    12721 aatctacagc taagtggttc caaaatgata gagaagaata tgaaagagca gcatacgatg
    12781 aagatagaga aagaagaggt tcaaactgtg gaggttcaga ttcagaagga aatagaccta
    12841 gaaactgtga aagatttaga agagaagctg agataagaga aagagaagca agagaagcat
    12901 tttgtgaatc ttcagagaga aagaaagaag cattagcata tgaatgtgaa gctagaaaat
    12961 tatgggaaca agcagaaaaa tactgggatg aatattcaaa atacaactat caaggaatcg
    13021 aatatttagc agaagctgct agattatttg atgaaggtat ggaatgtgaa gctagaagaa
    13081 atggaaataa tggaggaaac aataataatt gttgccacaa atgccataaa tgtaattgta
    13141 actgctgtag aaaataaaaa aattcattga caaatcaata gttaaaatat atcatattat
    13201 gtataataaa gagaaaattc agaaaaaaat aatgattata agaaatataa gtatatttat
    13261 tagacaaata gtgctcagtt agtgaggtga gtacaatatg attaaactcc catcctctag
    13321 ctcttgatag agggtgggag tttttattat tgatatatta aatgaggata atattgtaaa
    13381 attaggaggt aaaaaatgaa acgtattaaa acatcaagta tgaaagaaaa ggtagatgaa
    13441 aagatattaa gagagcaagt aagttctata atagaagata taagaaataa taaagatatt
    13501 gcacttaaaa aatacaatga gaagtttgat agaaatacaa gagatgaatt tagaattact
    13561 aaagaagaaa taaaggaagc ttataagcat gtagatgacg aatttataaa taacttaaaa
    13621 attgctgcca aaaatataaa agaatttgct aaagctcaaa aatcaagttt tgaaaattct
    13681 tttgaaaaag aaatttatcc aggtgtaatt ctaggtcaaa caaatattcc aatagagtca
    13741 tgtcttgcat atgttccagg aggtcagtat ccattgtttt caacagctct tatgcttata
    13801 atacctgcaa aagtagcagg agtaaaaaga atagtggcat gttcaccaac tatgaaaaat
    13861 actgaaaaga taaatcctaa aaccttggta gctatggata tagcaggtgc tgatgagata
    13921 tatgcaactg gaggagttca agctatagca gcatttacat atggaacaga aaagattaaa
    13981 ccggttgaca taattgtagg cccaggaaat aagtttgtaa ctgaagctaa aagacaatgt
    14041 tatggacaag taggaattga ctttgtcgct ggaccaagtg aagttcttat aatagctgat
    14101 gaaacttcaa agccagttta tattgcagca gatttattag cacaatgtga gcatgattta
    14161 aatgcaagag gtatattatt gacaaatagc ttagaaatag cagaagaagt tgaaaaaaat
    14221 atagaaacta tgctaaaaga tttgccaaca aaagatatag catatagttc atggaaaaat
    14281 aatggagaga taattctggt tgatgatatg gaagaagcca ttaaaataag taatttttat
    14341 gcaccagaac atttagaaat tgcagtaaat aagtgtgatg atatttttga cagattaact
    14401 aactatggtt ctttatttat tggaaatctt tctgctgagg tatttggtga ctatgtttca
    14461 ggtaccaatc atacattacc aacgcttaaa gcatcaagat atactggtgg tgtttgggtt
    14521 ggaactttta tcaaaacttg cacaaagcag atatttaatg aagaagctat agaatcatta
    14581 gcacctgtag ctgaaaagtt ggcaaaagaa gagggattat atgcacatgc aaaggcagct
    14641 gaggttagat ttaaaaagta gtaaaaaatt ctattttcgt cagtcgagat ttagtattag
    14701 actgagataa ggaaaacgcc gagaacatga ataaatacta tattttgtgg gtaatcggcg
    14761 tttcttttat atctgtatat gataggataa tactacctgt gtgtttaaat gataacttga
    14821 tatttctttt ctaaataatg tttatgaaat agttaatatt tttagttaat acttgaaaaa
    14881 aacttttgct aactgtgcaa attcatctgc atttgtcaat atagctgggt gtcctccatg
    14941 actaaaaatg tgaatacttg cttttcgaat aaaagttgcc atttgtttgt actcttcttc
    15001 aagattgtga cgacacattt cgtcttcctt acttcctata aacaaaattg gcatttctaa
    15061 tttacacaat tctttatgaa acaaaggacg tttctccttt gcacattgca atagagcttt
    15121 tgtatcaaga ttaacaacat tttcccaatc ttttccctga caccattcat agaattttcg
    15181 tgcttgaata tcttgctttg atttttccct tccagtgatt agattatcta tgaagttatc
    15241 attaagagta cgcccatcaa agctatctgc tataattgct tcaactaaat cgggacgttc
    15301 taatccagta ttaacagctg cccatgctcc tccacttgtt ccaattaagc caactttacc
    15361 acaattcaaa tgttcaatca gtgctatcgt ctgtaaggct tcatcatgcc acatgtcagg
    15421 agaaaattga gaaactctat ccgactgtcc attacctaaa aaatcaatta agatacatct
    15481 aaagttttct acatataatg gcataagtgc tttaaacata ttagaagaag cagtattacc
    15541 atgcaggaaa actatcggtt taccttgtcc atattcttca taaaaacaag cattaccttg
    15601 atactgaaaa tatgacatat attgtcctcc tttttatttg ttaagttaat tataacaata
    15661 taggtatgaa tgaaaaacct catgttcttt cttagaataa aaatgtgcca cgcgtaaatc
    15721 gtgacacatc tctaattata aattttgctg tttaagtatt ctttgtatgc ttttctctgt
    15781 caaaaagtat ttctctgata actgcttgat gctcattcat ttttggaagt ttatacagat
    15841 ttgagaatta cgagaagcta agacttgttt ggtgtttgtg ttttcccccc aatgcttttt
    15901 gtgctcttgc tttttgggaa tataaatcac tttaccatct atatattctt gcacttgctc
    15961 aatcagttct ttaggcagta agtcaatcga attttgatag ctcattttgc acctcctaaa
    16021 taattgctct ttaggattag caaaggctac tgctactcat aattaaaaat aaaattttgt
    16081 tattatgtac aatagccttt gctatgcaca agttccaatt cccataaact caatactcct
    16141 ttctgattta aaaaattcat ctgaacattg atttcgtttt taaaatagag ttcaatgaca
    16201 aatttacatt tctattatat atattcaggt agctaattgc aactgtcttt gtatgaggga
    16261 attttattat agtcaatact ataatatgta tttatatcat caaattaata tgaacagttg
    16321 aaaggaacat gaataataaa acttagcagg aagaataatt ataaagcaga caatagagaa
    16381 atttgattct aaggtttttt tgaaaattca ttaacaaatt taacttgtaa atattatact
    16441 aaacttaata aataaagttt ataaagtaag gagttgtcta tgaaaaatat agttggaaaa
    16501 tcacaaacga taaaaaaagt aaatgaagac ttaataaaaa atattataaa aaatgaaggt
    16561 cctataacaa aactagaaat ttcaagcatt actgaattga gtttagctac agttaataag
    16621 attgtagagc agttagcttt aaaaaatgag gttaaagtaa gtggactaag tgaatctact
    16681 ggaggaagaa gagctcaatt atttgaaata aatgcaaact tagaacacat aatagcttta
    16741 tactattata gaaattattg tataggggta gttgccaatt tattaggtga aataatttat
    16801 caagaaaaat ttaatataag aatggatacg tattaaaacg ctaaccaaaa tacttttttt
    16861 gttatagata ctttaataaa aaaaagaaaa aggaaataat ataagagcca ttggaattgg
    16921 cgtcccagga gttgtaaaaa aaggtatagt taaaaatata ccaactataa aaagttggga
    16981 aggtataaat ttagaaaatt taataaagag taaatacaat actaaattat ttatagaaaa
    17041 tgatacaaat attactacca ttgggattta tcaaaaacag tataaagaaa aatataaaaa
    17101 tatggctctt atgtatctag aaaatggtat tggttcaggt atagttataa atgacgaatt
    17161 atatttaggt tctacaaatt ttgctggaga attaaattat ctaaatatag aatttggtaa
    17221 gtataactct aataacttaa atcttgaaga gtatatgtat ctggtatatc tggttgtgat
    17281 tctcctaatg actataagat tataatggat gaaatattaa aaattgggat taacaaagaa
    17341 aaaatatatt tagaaaatga tgcagtttta gctttttatg cacaagctga ttcacatggt
    17401 ttagtaattg tggctgggac aggttcaatt atattaggaa ttaaagaaga tggaggataa
    17461 tatttcagag ttcaagggtg aatggtaaat tgtcatagat aataaataaa attttcagag
    17521 ttactttata tagtttctaa agtaactctt ttttaaattg aatttagtga taaattattg
    17581 aatagtattt ctaaacaaat aaaaaattaa tataaacaaa gacttaatta tactaaatta
    17641 taagtcaaac taatataaac ttatataaaa aaggaaaacg tctaaagtat tggaattact
    17701 gtgatttagg tatggtatta aaaaaacata aaaaaacata aaaaaattgt tgaaaaaact
    17761 ataaaaattt tgtataatta aagatttgaa aagtgcggta tacaaagcca attcttttgt
    17821 atataatata tataaattca gaaaaaggaa gggatatgta tggccaggcg gttattttta
    17881 gaaaggattg gacttatatt tttaggttca gcaatattag catttggagt ttataatttt
    17941 tattatttaa acaacataac agaaggtgga gtgttaggta ttttactact gttaaaaaat
    18001 ttattcaata tacaaccagc aatagcaaat gttgtaatag atggtttact acttttagta
    18061 ggatataaat ttttcggtaa aaaattcctt atatattcaa tagtagcttc tataactttt
    18121 tcagtgttat atgacttatt tgaagctata ggacctctag taccacaatc acaaaatatg
    18181 cttttatcaa ctattttggc aggtgtaact gttggaactg gtgtaggtat agtagtaaaa
    18241 gcaggttgtg catcaggagg agacgatgct ttagcattag taatttctaa gactacatct
    18301 ttgaacatag ggcaagttta tttagcaaca gatgttattg tattgttgtt atcattattt
    18361 tatctatcag cttttgatat attttactct ttgattgctg ttacaattag tgggaaggta
    18421 attgatttta tttattatca tggtaaaagt ttggatatgg atataagtaa tgatatagtt
    18481 ccagaatgtt aatataaatt aaataatttt atattttatt aggggtggca agtttgccac
    18541 cttttttgtg tctaaatatt tacataaagt ataacctcat ctaggttttt ataaatttca
    18601 aatataaaat tatgttgaaa tgactaggaa tacgattact agaggtgctt tttaaaaacc
    18661 caattttata tttatgaaat actaatcatt aatggatgtt tcttaatcct atctttatac
    18721 ctaaaatgat aagataaatg aagtagcaat acaaaactaa aatttgtaaa agagattaaa
    18781 gtaaatggag gagctaagat gttggatata gttatgatag cattgttatt cataggattt
    18841 gtttccatga agttacttgc tgattggtgt ggaaaacaaa ctgaaaaaaa ataatgtaat
    18901 gtatggaggg attacctatg tggtttctgg cagttgtaat tataatgtta ataatatatt
    18961 tggtatatgc gcttattaat cctgaaaaat tttaaacagt ataagactaa taagtaagtt
    19021 gaattggggg gaacgatttt tatggtgcag atagtaatag tgttagcgat ttttatgatt
    19081 ttagtaatac ctatgggcaa gtatttatat catatagcta ctaatcaaaa aacatttgga
    19141 gatagactat ttgataaagt ggacaatttt atatataaag tatgtagtat agataagaaa
    19201 aaagaaatga actggaaaca gtatgcctta gctttattat ttacaaatgc agttatggta
    19261 tttataggat atatcatact tagaactcag agtatgcata tttttaatcc aagtggaatt
    19321 aaaagtatgg aacaaggact atcatttaat acaataataa gttttatgac aaatacaaat
    19381 cttcaacatt attcaggtga atcaggactt tcatacttta gtcagatgac agtgataata
    19441 tatatgatgt ttacatcagc agcaacagga tattcagctg ctatggcatt tgtaagaggg
    19501 ttggttggta aaaagaaaac attgggaaat ttttatgtag atttaattag gataacaaca
    19561 agagtacttt taccaggagc tttaattatt gggattatat tagttacaca aggagtacca
    19621 caaacttttg ctgggacaga aacggtgact actatagaag gaaaacttca agatatagct
    19681 agaggtcctg tagcggctct tgaatcaata aaacatttag gaacaaatgg tggtggattc
    19741 tttggttcaa attcatcaca cccatttgaa aatccaacaa taatatcaaa tatagtagaa
    19801 atattatcta tgatgatatt accaggagct tgtgttgttg catttggtta tatgataaag
    19861 aataaaaaac aaggttgggt tgtgtttggt gcaatgtcaa tcatattttt aataggttta
    19921 gtagtttgtt ttaaagcaga aagtgcagga aatcctattt tatcacaatt agggcttaat
    19981 caaagtatgg gaagtatgga aggtaaggaa gttagatttg gtatagcaca atcatcatta
    20041 ttcacagcag tgactacttc atttacaaca ggtacagtta ataatatgca tgatacacta
    20101 actcctttag gaggattagt accactttta aatatgatgt taaatgtagt ctttggtggt
    20161 aaaggcgtag gtcttatgaa tatgttgatg tacgctataa tagcagtatt cctatgtgga
    20221 ttaatggtag gaagaacacc agagttttta actaagaaaa tcgaaggaaa agaaatgaag
    20281 cttattgctt tacttattat attacatcca cttttaatac taatgttctc tgggctttcg
    20341 gtagcagtac cagcagggct tgaaggaatt tcaaatcctg gattccatgg attatcacaa
    20401 gtattgtatg aattttcatc ttcagcagct aataatggtt caggatttga aggtctagga
    20461 gataacacta tgttttggaa tatgacaaca ggtatagtta tgttctttgg aagatatgtg
    20521 tctattatag tattactagc aatatcaagt ttgttagcat ctaaaaaagc tgtaaatgaa
    20581 agtataggaa cacttagaac ggataatttt acatttacaa tagttttagt acttgttgtt
    20641 ttaattgttg gtgctttaac atttttccca gccttagcgc ttggacctat ttcggagcat
    20701 ctagtgttat ggcactaaaa aattgggagg gagtaaagtt ttatggatac taaaaaaaca
    20761 aagtttatta caaaagatat tttcaaaact tccattatag aagcttttaa aaaattaaat
    20821 cctaaatata tgatgaaaaa tccagttatg tttgttgtag aaattggatt tatagtaaca
    20881 ttgatactca caatagtacc tagtttgttt ggtgatgaag gcaataattt aagagtttat
    20941 aatgggattg taacaataat cttatttata acagttcttt ttgcaaattt tgctgaggct
    21001 gtagctgaag gaagaggtaa agctcaagca gatacactta agaaaactag aaaagataca
    21061 gtagcaaggg ttatagatac gttaggaaat gaaaaaatga taagtgcaag tgagctaaaa
    21121 cttggtgata tcgttttagt aaatgcagga gaagttatcc caaatgatgg agaagttata
    21181 gagggtatag cttctgtgga tgagtcagca ataactggag aatctgcacc tgtcatgaga
    21241 gaatctggtg gagattttgc atctgttaca ggtggtacta cagtggtcag tgactggcta
    21301 aaaataagaa taacaacaaa accaggagaa tcattcttag acaaaatgat agctcttgta
    21361 gaaggtgctt caagacaaaa aacgccaaat gagattgctt taaatacttt gttagtaggg
    21421 ttaacactta tatttatggt tgttttaata tctctttatc caatggcaaa ttatgcaggt
    21481 gtaaagattc caatttctac tatgatagct cttttggtat gtttaatacc aactactata
    21541 ggtggattgt tgtcagctat tggtattgca ggtatggata gggtaactag atttaatgta
    21601 attgcaatgt caggaaaagc agtagaagct tgtggagacg ttgatactat gattttggat
    21661 aagacaggta cgattactta tgggaataga cttgcatcag aatttataac agttggaaac
    21721 gcagattcaa aagacttaat aaattattct gttatgtgtt cattaaaaga tgatacgcca
    21781 gaaggaaaat ctatagttga tttaggcatg aaattaggct caacaggtaa gacaaaagag
    21841 gcagaggaag ctgagtttgt agaattttct gcacagacta gaatgagtgg tattaaccta
    21901 gctgatggta gagctataag aaaaggtgct tatgatagca taataaaaag agtaaaagaa
    21961 tctggtggta tagtaccaga agatttagaa gaaaatgtaa atcgagtagc taaactagga
    22021 ggaacacctt tagtagtgtg tgtagataat gggatatatg gaattatcta cttaaaggat
    22081 acagtaaaat cagggcttgt agaaagattt gctagacttc gtgagatagg aataaaaaca
    22141 ataatgtgta caggagacaa tcctttaaca gcagctacaa ttgcaagaga agctggagta
    22201 gatggattta ttgcagagtg taagccagaa gataaaatag atgctataaa gaaagaacaa
    22261 tctgaaggta aaatagttgc aatgacaggt gatggaacaa atgatgctcc tgcacttgct
    22321 caggcagatg taggtcttgc aatgaatagt ggtacaacat ctgcaaaaga agcagcaaac
    22381 atggtagatt tagattcaga cccaactaag atattggaag ttgttgaaat aggaaaacag
    22441 cttctaataa ctcgtggagc tttgacgaca tttagtatag caaatgacgt tgcaaaatat
    22501 tttgcgatta taccagctat attcactctt gcaatacctc aaatggagat attaaatgta
    22561 atgaaacttt ctacatcatt tagtgcgata ttatcagctt taatattcaa tgctataatt
    22621 atcccatgtt taatacctct tgcaatgaag ggagtaaaat atagacctat gaaatcacaa
    22681 gctatgttaa tgagaaatat gcttatattt ggtcttggtg gagttatagt accattttta
    22741 ggaataaaat taattgattt attgattaca cctttagtaa tggttcttaa tttaggttaa
    22801 taaatggagg atataaaaat gaaaacatta aagccagcat tacttgtaag tattgtattg
    22861 ttagttgttt gtggacttgt gtatccactt gttttgacag gtgtaagtca agttgcattc
    22921 aaagataaag ctaatggaag tatgatagaa gtaaatggtg taaaggtagg ttcagaactt
    22981 attggtcaaa gctttacaga tgcaagattc tttaaaggaa gagtttcatc agtaaactat
    23041 aatacttata caaaagaaga tttagtacca gataaagatg gaaatacatc ttatggaggt
    23101 gtatcatcag ggtcttttaa ttatggagct acaaatccag aacttcgtga tagagtgcaa
    23161 aaagatatag aacagtttct aaaggataat ccaactgtca aaaaagaaga tataccaaca
    23221 gatttgctta cagcatcagg ttcagggctt gaccctaata taagtccgga ctctgcaaaa
    23281 attcagatac ctgctgtagc aaaagcgtca ggaatatcag aaagtaaatt acaaaaaatt
    23341 gtagatgata atacttccaa aaaagttttt ggagttttag gggaagatag agttaatgta
    23401 ctaaaggtta atgtagaggt cgcaagaata ttaggtctta tatagcattt tgtagaattt
    23461 tagtaacaaa atatcatgca agatttaatt taaaggttag attttaaaga gtgaaaatcg
    23521 ataatgattt tcactttttt atttgaatat tactaatatt tggaataaag cgattgtaag
    23581 tataaaatcc aaaaaaaggt tgcattatca aaatgataat actataatat atttatcgtt
    23641 atcaatttga taatagattt tgacatatag gaggaaatag tatgttatat aataatgcat
    23701 tagagttgat aggaaacaca cctgtagtaa ggctgaataa tttaggttgt actaacgggt
    23761 gttctaacat atatgtaaaa ttagaaaaag taaatccagc aggaagtata aaagatagag
    23821 ccgtttatga aatgctagaa ggtttagaga aaagaggaga attaaaaaag ggagatgtac
    23881 tagtagaagc aactagtgga aatactggta ttgcattatc tatgatagga aaattaaagg
    23941 gatatgaagt cgtaattgta atgcctgaaa caatgagtat tgagagaaga gatttaatga
    24001 aggcttatgg agcaaatttg gtacttacag atggtaaagc tggaatggca ggttccatag
    24061 aaaaagcaaa tgaactttta aaagaaaatc caaactataa aagcttaaaa caatttgaaa
    24121 ataaagataa tccaaatgca cattataaaa caacagcagt tgaaattatg aatgatgtta
    24181 aagatttaga tatatttgta tgtggagttg gaacaggtgg tactttaata ggaactgcaa
    24241 gatatttaaa agaacaaaat ccaaacataa aagtagttgc acttgaacca aaaaaatctc
    24301 cagctatatc agaaaacaag actggacctc ataaaataca aggtataggt gctaactttg
    24361 ttcctgaaaa ttatgattct agtgtagttg atgaaataat attagtagat gatgaagatg
    24421 catttgatac agttaaatta cttgcatcaa aagagggaat tttagtaggg atatcttctg
    24481 gagcaaatat atttggtgct atagagatgg caaaaagata tccagataaa aagatagtta
    24541 cagtagctcc agatggagtt gataagtata tgtcgatggg aatattttaa taattttatt
    24601 tgagggagtg aatactttgt ttaagaaaat aaataaagat attgaatata taatgaaaaa
    24661 tgatccagca gctaggtcta agatagaagt ttttttactt tatccatcag ttcatgcaat
    24721 gataatgcat aggatggctc atgctcttta taagaagaag aagcttttta cagcaagatt
    24781 aatatcccag atatccagat ttatgactgg tatagaaata catcctggtg ctaaaatggg
    24841 agaaggtata ttgatagacc atggaatggg tgttgtaatt ggagagacag ctgaagtagg
    24901 taatagggtg acaatatatc aaggagctac tttaggagcc acaggaaaag atactggaaa
    24961 aagacatcca actgttggtg atgatgtatt aattggtgct ggaacaaaaa tactaggtcc
    25021 tttaaatata ggttcaaatt caaaaattgg tgcaaattcg gttgtcgtta aggatgtacc
    25081 taatggtgca acagttgttg gtataccagc aaaaatagta aaaataagaa atctagaacc
    25141 tgtaaaaaag aataaaaaag aagtagacta tgagtatgat gaattagata atgtatatta
    25201 tatataggtt ttgtataacc ataaaataaa ctttataaaa attattttta aaaggtattt
    25261 ttttcaaatt tgagggcata ataaaaaaga actgaatgtt acagttttgg ttcatcaatt
    25321 tttgataaac aagattttaa atttgtagcg tctaggaggt ttttattatg aaagcaaatg
    25381 ttaatcaaga tacttgtata ggttgtggat tatgtccatc aatatgtcca gaagtatttg
    25441 atatgaatga tgatgggaaa tcacatgtta tagttgatga agtaccaagt gatgctgaag
    25501 aatcagcagc agaagctaga gaaagctgtc cagttgatgc aatagatgtg cattaataaa
    25561 ataaatgcct ataaaaattg aattttcaat ttttataggc atttgtcttt tattcagtca
    25621 gtatttcaac acctgtttct gtaactaaaa ccatacattc ccattgagca gataatttac
    25681 catcttttgt ataaatagtc caattatttt cttcatcaac gaaaatttcg tgagttcctt
    25741 catttaccat aggttctatt gtgaatatca tcccaggaac taataacatc tcagtccctt
    25801 ttttagatac ataacttaca aaagggtctt cgtgaaagct taatccaact ccatgaccac
    25861 caatttctct aacgacagag tatccatttt tctttgcata agagttgaca gcatcaccta
    25921 tatctcctaa gaatccccat ggtttggcaa cctcaagacc tttttggacg cattcctttg
    25981 taacttgaac tagttttttt gcattttcgt taacattacc taccataaac attcttgaag
    26041 cgtctgaata gtatccatta aaaatagtag aaacatctac atttataata tctccatctt
    26101 ttaagataat gtccttattt ggaataccat gacaaacttc attatttatt gatgtacata
    26161 cgcttttagg aaatccatta tagcctagtg gagcaggaat agctccattt tgtagtgtaa
    26221 attcatgaac taacttattt atatcttctg tagatattcc aacttcgatt ttatctgaaa
    26281 tataatccaa aatttttgtg tttattacag cacttttttt tatttcctca atttgacttt
    26341 cattttttat aatgtcatga gttggtacaa tatgacctaa tttagcaaat gaatctattt
    26401 tattatccat atccatatga cattttttat attttttagt acttccacac caacagctat
    26461 catttctatt taacttcata acttttcatc cttcttttat tatttattta aattatgggt
    26521 tacataaact attttaaaac ataaccatta taaatattat aacataaata ctaaaaaatc
    26581 ctttatagat agtgatttat tcaaaatata aattatcatg tgattattgt tgatgaaaag
    26641 agtacagtta aatgtattat tggatagtag tacacttaat agtatagttc aagtttttca
    26701 agaaaatcat atgtcagagg acaattttcc tttaaagtat tttttgaatc ttcatcaaga
    26761 taatagtgta caaatgattc tgcaaaaaat tcttctataa acttgcttat atatgcatgt
    26821 gcaatttgtt tagggtcata aagtttgtat ctttcctgag caaatacttt cataaactct
    26881 tcagaatttg attttttatt taaaacgttt ttatctatag catgtgcagt ttcatgtaat
    26941 tctaaatttt tagatgaatg tacatttgta tagctaggat tactataacc tattttagca
    27001 actatagaat tatttctata tataccaggt acatctttcc aagtcttgcc tgatcttacc
    27061 cagcatggag gtaattgata ttttaaatca ctaaattctg gttcatcagt tagatttgaa
    27121 tttattaatt ttatttttat atccttttct ttaagtgctt gtaaatattt aatatttatt
    27181 tttgcaagtc tgcttttcat attttcaact tcatctttat cataattcaa gtcatcagga
    27241 agtataagca tttgttcaat tatatctatg ttactgtctt ttatatcttc agactcttca
    27301 tcaaatttat attgaagatt atcattttca tagatagtta tatttgtatt attttccata
    27361 gaataagagt gaatatcctc taagtttaaa atattcattt gttgtaaaat atgttttgtt
    27421 tcgccactcc atactactaa agaaagtgaa ttaaaattaa ttagtggatt ttcttttgct
    27481 tttatatcat tgcttatatc gacatcaaat acatattcaa ttgagtcctc tatgttaagg
    27541 ccatttgtat tctttttaat atacaaatac gcttgtttta agtctatata aatctcatct
    27601 aaagattcgt cataaaattc tgataaatta ttagtaaaga gttcttcact taaaagttca
    27661 tttttatcag ttatactttc gattaaaata ttaatttctt ttatcatatc gtaaatactt
    27721 atttttctat ttgcttcttc actagataca ttgcatggcg caagagcaat gcaataaaaa
    27781 tctttttctt ttttataaaa ggctttaagt gattttgata aaagtgtaaa gtctacacct
    27841 atctgtaaat ttaccttaag tgaatcattt tgtgataatt cagtattatt tcttttagct
    27901 gtatttaaat tattttccat aatcattgcc ccctttttat tagggtatca taattttttt
    27961 atatgtgtca atttattttt ttgaaaatta taattttttt gaaaatttta ttttttataa
    28021 tttgttaatt ttttattata gaaataaaga tgttattatt atgtcaaaat ttagcattag
    28081 attcatgtag agtatatttt atatacatat attataatta actttttgaa gattgcatat
    28141 tcaaaataca caccattttt tttaattcta taatataata tttatatatt taatgttagg
    28201 atgtgattta agatgtattt tacatatatt ataagatgta aagatgattc tctatacact
    28261 ggatatacca gtaatatagt tagaagaatg aatgaacata agttaggagt taattcaaaa
    28321 tacacaagag caaaagggtt taaaaaacta gaagtttatt ttgtgactaa tacaaaaagt
    28381 aatgctatga agttagaata ctatataaaa aaattaacta gaaataaaaa attgtctata
    28441 ataaaaaatc caaatatact tataaattca attaataata aaactgatta tattattggg
    28501 aaagaaatag aataattaac ataaacattc atagtaacat tataatgagt acatatagtg
    28561 taaaaacttg acaataaata ctattgtaat ataatgaagt tatgaatata gtaaattaaa
    28621 atagctaggg gagccaagag ctgagaggta taccgaccct tacacctgat ctggataata
    28681 ccagcgtagg aaagcttagt aaaaattcaa gtatgtatta tttgtgatat atgctatttc
    28741 taagctatac ctattgtagg tatagctttt ttaattaagt tatttaaatt aaactttagg
    28801 aggcaataat gagtaattat aaaataccaa cacttacaat agccggttct gactcatctg
    28861 gaggagctgg gattcaggca gatttgaaaa cctttagtgc aattggtact tatggcatga
    28921 gtgtaataac agctataaca gcacaaaata ctcaaggagt ttttgctgta gaggacttaa
    28981 ataagaatat aataaaaaaa caaatagagg cagtctttga agatatacct ccaagagctg
    29041 taaaaatagg aatggtttca agtcctgaga ttatacttga aatagttaag aatctaaaga
    29101 aatacaatcc aaaatatttg gtggtagacc cagtaatgat atctaaaagt ggatattatc
    29161 tattaaagcc agaggcaaaa gaaaacttaa ttaagtattt gataccactt gcatacataa
    29221 ttacaccaaa tataccagaa gcagaagaaa tcacaggaat aaaaatacat aatgtagatg
    29281 atatgaagag agtaggaaaa gaaatactgc aacttgggcc taaatttgta cttatgaaag
    29341 gaggtcattt agatggagaa gcggtagata ttttaattgg taaaaatata tttaaagttt
    29401 ataaaagtga aagaattgat aaaaaaaata cacatggaac aggatgcaca ttatcttctg
    29461 caataacatc ttatctagca ttaggatatg aaataacaga agcagtaaat tttagcaaaa
    29521 tctatataac agaagcaata aaaagaagct ttgatatagg tcatggagta ggaccagtac
    29581 atcattttta taaatttgaa taataaaaaa atattggagg tagaatatgt ataatttaat
    29641 taaagacgta aaaaaattaa atccattggt aattcattat actaataatg taactataaa
    29701 tgattgtgct aatgcaactt tagctgtagg agcaagtcct cttatgagtt tttcatatga
    29761 agaagtagaa gaaatggtaa gtgtagcaaa ctctgtagta ataaatatag gaactatgaa
    29821 ctcaaatatg ttggatttgt tcctcttagc tggaaaagca gcaaataagt acaataaacc
    29881 cgttgttttg gacccagttg gagtatttgc aagcaaagcg agagcagaac ttacaagtag
    29941 acttttaaat gaagtcaaat ttagtgttgt taaagggaat gtgtcagaaa taaagtttat
    30001 aggtggtttt aatgtaaggg gtaaaggcgt agattcattt gatgaagaag attctactga
    30061 tataataaga aaagttgcta aaaagcttga atgtatagtt gtagcaactg ggaaaataga
    30121 tataataact aatggtaaaa gtacatacaa aataaacaat ggaactgata aactgaaagg
    30181 aattacaggc actggatgta tgactgctag cttaattgca agttttatgg ctgttactga
    30241 gaatatatta gaagcagcaa caatgggtgt tcttacaatg tctttaagtg gcgaattggc
    30301 taatttaaat aatccgccaa taggtacatt taaagaaaat cttatgaatg ctatttatca
    30361 aatggacata gatactttaa gtaaaaattc taatattgaa tttttaaatt aataaagagt
    30421 aagggagact taaaatgata gataaagaat ctttaaaaaa atgcttaaga ttgtatttaa
    30481 taactgactc tgaaatgctt gaaggtagag acttttataa atgtattgaa gatgcaatat
    30541 cttctggaat aacaactgta cagcttagag aaaaaaatac ttgtggaaga gaatttttaa
    30601 gaaaagctat gaaacttaga gaaataacta aaagatatgg agttaagttt ataataaatg
    30661 atagagtgga tatagcactt atttgtgatg cagatggggt acatgtagga cagagtgata
    30721 ttgatgtgag agaggttaga aaacttatag gaaacgataa aattctagga gtatcagcaa
    30781 gaactttaga agaagctatt tgtgcaaaaa atgatggtgc agactattta ggcatagggt
    30841 ctatattctc aacatctact aaattagatg caaaatcagc ctcatttgaa actgttaaag
    30901 aaattaaaga aaaagtagac atgccatttg tactaattgg aggtataaat ttagacaata
    30961 tagataaact taaatgttta gatagtgacg ggtatgctat aatatcggct atactaaaag
    31021 ctgaagatat atctaaagaa gtagaaaagt ggacattaaa aatataaaat tggctctagt
    31081 agtgaaaaaa atggaaaaat ttgatataat ctaagagtaa aatttaagaa attataaatg
    31141 ataaactttt ctacatatac tttttaatca agatatatgt agatttggtt aaaaaggagt
    31201 tataaatgat taggatattg ttagtatgtg ttggaggcat gtcttccact ctattggtaa
    31261 ataaaatgga gaaggacgca aaaaagagaa atatagattg taaaatatgg gcagttggag
    31321 aaggagatat aaaatcagag cttgataact tcgatatttt acttcttgga ccacaactta
    31381 gatttatgtt tgatgatgta aagtctatag ttggagatag agctccagtg tctataatag
    31441 atatggtaaa ctatggtact tgtaatggtc atgctgtgtt aaattcggtt ttagaaatat
    31501 taaaataaat aataaaagtg gattctatat aatagagtcc acttttatta tttgttatta
    31561 atggatttaa aacttagctt accatttctt tttttaatct ccacatagca agtgaaaaac
    31621 ttgcacagca caatattaaa aatagtagga taacaggtag tatatcttca ataagaacag
    31681 tctcaccaaa tattaagcta cgtaaagcgt taataacatg ggtaaatgga ttgagcatca
    31741 ctaccacttt taatcctcca gataaatttt ctatagggaa aagagctgaa cttaaaaaga
    31801 aaataggaag tacaattgca gtcataattg tttcataaac tatctcattt ggcaacaata
    31861 aacttataga ataagctaga cttgataaaa agaaggcggt cataaataca agcactgtca
    31921 taagtaggat tccaccaatg ccagattcta tcgttactga aaagaatata cttactatac
    31981 acaaaatagc tacttctatg aaggaaacta agatagcttc taataattga ccaaggacga
    32041 ttgaatacct actgataggt gcaattaaga ctctatagaa acttccacta ttcttcatta
    32101 taaagttgat gataccacca ctactacaag aagaaaacac aaccagtata attatacctg
    32161 gtagtataaa agcagtataa ttattgatat ttatattatt catagtttgg tttgcaatag
    32221 aactataaag cacaagccaa agaaaaggtt gtaatatagt aactataaat gagattggat
    32281 ttttaaaacg ccacttcata ctacgccata agatatttaa cattcccatc cctcctttag
    32341 gcttttttta gaacttgtaa gtgctaaaaa tacatcttcg agacttggtt ccacaatttc
    32401 tattgcatca aattctatat catgttctaa aagccattta tttattaaag taaaagcagt
    32461 tctactatcg tttacactta taaaaattga attttctcgt acattcataa actttactaa
    32521 accagtaccc ttaattgcat cattatattt ttttatatct tcagtattat ggaaagttat
    32581 acgtattata ttttgtctaa tgtaactacg taaactggat ggtgttcctt gtgctaaatc
    32641 ttttccattc ttcataatac aaatgttatc acttaattgt tcagcttctt caagataatg
    32701 agtagttaga aatatagttg tgccatactc atatctaatt tttaataaca tatcccacat
    32761 agactttctt gaatctacat ccataccgac agttggttca tctagaaata gaattttagg
    32821 agatgatacc atattcatag ctatgtccaa tctacgtttt acaccacctg aatatgatga
    32881 agtaggatat tttaagtaac tagataagtc aaacttatca attaaagagt ctattctttg
    32941 ttttgcaatc tgtggtttta ctttatacat cttgctttga aatatcatat tttccataag
    33001 agataagtgt tcatcaatag agatttgttg tgctacacaa gcaatttgag tacgtatcca
    33061 agaaggatta tctactaaat cttttccaaa cattgttaca tttccagatg taggcttgta
    33121 aaaagtagtc aaaatattga taagagaaga tttaccagca ccattagggc cgagcaaaga
    33181 aaaaatttct ccagaattta cattaaagct tagaccattt aaagctttca caccattttt
    33241 atattctttt actaaattgt ctatttcaac tgctaacata tattattcct cctctttaag
    33301 tggaaatatt atctctgtaa tatagttatc tggttttcct tttaccaaca tacctggtcc
    33361 tttaataaat acttctctcc aaggagtttg tatttttata ttattttcat gaatatattt
    33421 aaatatcatt tcatacgttt ttggcaaatt actataagaa cctatatgag taaaaaacaa
    33481 agcttttgtt ttaggaaatt cttttgtagt tatacccatg cgatttggag tctcagcagt
    33541 tggaacacat aattccattt ctgcaacacc agttttttgg tcaacatcat agtagcaaaa
    33601 gaatggtgca ccgttagact ttccttttat agctttaaat acatttggaa aatattttgt
    33661 tgcctcagtc ataggtccat tataacgcat ggtagctact gtgactgatt caatattttt
    33721 gattttataa ctcatttgtt tacctcctaa tgtgtattca tatttttatt agatttttaa
    33781 gcatcaatac atataagatt ttgattagta gaaagcatat aatcttatct cgtttgcttg
    33841 tgttcaagtc taacataaca taaaatatat atcctctcat ttgatgctcc attttgtaaa
    33901 gttattattt aagctttatt ttagtttttt agtaaattta aattaaaata aaataatgta
    33961 taaaaaaagt gtttacaaac taagtgtatt aatcgtataa tacacttaat aggatactag
    34021 ataaggtctg aaataaagac atattttttt aaagtaagtg tactatcgta ttaatacact
    34081 agaataggag gaaccatgaa ctttgaatta gataatacaa ctcccattta tttgcaaata
    34141 gtaaagtata taaagagaca aatagtaata ggagagttga aaccagggga tacaatacca
    34201 tcaagaagag aaatggcact taatctaaaa gtaaatttaa atacggttca aagagcatat
    34261 aaggagatgg gggatatgaa tataataaat acttttaaaa atcatcaaag cagtgtaaca
    34321 attgatgaaa atatattaaa aaatttaaaa ttagagctta taaatgaatc attatctgtt
    34381 tttttaaaag atatgaaagc aataaatgtt accaaagaag aagttttaaa gataatagaa
    34441 gataagtatt agttttttaa catatagaaa acttagttta gaaagtttat ttataagcat
    34501 attggatgtg gaggatagta aatatgatag aaataaaaaa tgtcagcaaa acatataaaa
    34561 ggatgcaagg gcttaaaata agaaagatag aggctttaaa aaatgtaagt tttaatatag
    34621 aaaagggaaa aataactgca ttacttggta taaatggcgt tggtaaatca actatgctaa
    34681 aagcaatagc agggcttata aacactgata gtggagagat tcgtatagat ggagaaaaaa
    34741 taaatgaaaa gatatacaat aaattggctt ttgttccaga tgtacaatct cacttcagta
    34801 atacaacaat aaaagaaaca tttgaattta tggaaatttt ttattcaaag tggaataaaa
    34861 aaaaatcaaa agaaatgatg aacatattta aattggatga agatgaaata attgataact
    34921 tgtcaaaagg aaacattgca agagtaaaat taatacttgg attttgccaa gacccagagt
    34981 acatacttct tgacgaacca tttacaggaa tcgatttgtt taagagggaa gaatttatag
    35041 gagtaatagc gcaatatatg gaggaaaatc aagctattat cataactact catgagatag
    35101 tagaaataga aagtttagtt gatgaggtta taattcttga tgaagggcag attatagctt
    35161 catttaatgc agaagaatta agagaaagag aaggtaaatc tatattagat aagatgaggg
    35221 aggtatataa gaatgaataa acttctatat ctaataaatg tagatttgag aagaagcaat
    35281 aagttttata tagcttatat atcatttttt tcattaatta cacttggttt aaatttattc
    35341 gaaattaata aatttaaaaa ttctaaattt attataaact tagcaatagg agattttgga
    35401 ggtatatttt atggaatagg tatacttagt aatcttggtt ttatccaaag tatattgttc
    35461 tttgggatgt tgggactttt tatatactat atttttatgt ggaaaagaga gtttttttcg
    35521 aataatcaaa gtatttatac actaatgatg ttacctcaaa ataagtttaa gatttgtata
    35581 tctaaatcaa tagctttgtt aacaatgata tatggttttt tgataagtca gatagcaaca
    35641 ttatttatat gtaaatatat atttaatttt atttttagaa atgtgccaat aatcaatatg
    35701 aactttgcca aagatttata ttatttaaat ttgaagggta taccaattga ttttatctct
    35761 tttatggcta tttatgtatt tttactactt atagctattt ctat
//
LOCUS       DBGJFK010000037        34033 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.037, whole genome shotgun sequence.
ACCESSION   DBGJFK010000037 DBGJFK010000000
VERSION     DBGJFK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34033
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.037"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     regulatory      162..205
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            306..1274
                     /locus_tag="ACOIAP_002086"
     CDS             306..1274
                     /locus_tag="ACOIAP_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HGZ2638969.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDRKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNTIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDLIDSVEGVI"
     gene            1276..1839
                     /locus_tag="ACOIAP_002087"
     CDS             1276..1839
                     /locus_tag="ACOIAP_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGZ2638970.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDLYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQIFTDYAD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            1847..2536
                     /locus_tag="ACOIAP_002088"
     CDS             1847..2536
                     /locus_tag="ACOIAP_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGZ2638971.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLEVLKNVTGKYGVLEVINSGSCFELPKDTLEEIKLIIKEKNIKKLFLESHWSYR
                     NRLEEMREYFEIPVIFKIGVETFDNDFRNNILNKNANFKTPQDVKDYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSNIKRDEELVRWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            2663..3391
                     /locus_tag="ACOIAP_002089"
     CDS             2663..3391
                     /locus_tag="ACOIAP_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HGZ2638972.1"
                     /translation="MMFNRGKWNKLDYNELLEYMMSMQDIKHRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISKGNWQEFLEVAEDTYYEEVMLQGMIIGNINSNFEETLYYVKRFI
                     PKINNWSVCDGFCSGLKSMKKYKENMYDILKKYVYSENPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKYEEETFLYIKNNNLDDFTYNKTLQKI
                     IESNRVDLEKKNIIRSMKRKTRRY"
     gene            3405..4079
                     /locus_tag="ACOIAP_002090"
     CDS             3405..4079
                     /locus_tag="ACOIAP_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGZ2638973.1"
                     /translation="MNNNEERIDKFLELQSKGFRFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNGDLEEEKVKEYEKSKKNTISNRKKVSTKKKVSNEKVL
                     SKSIEQIEFNDTGLKNAKPKKNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNMKP
                     KKVSNKKDIHIDDETIDELKTTRIRIDKEVWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            4105..4941
                     /locus_tag="ACOIAP_002091"
     CDS             4105..4941
                     /locus_tag="ACOIAP_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638974.1"
                     /translation="MNKIVKKSISLMIILTIFIFTLTACEKDEQPDSVDIQVEDKKEI
                     KIDEGNAKVLNIGKSEIINMDEGDKVDTSTKIENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKSVEVYAYEYEAEGKIVYVNLKENTIDIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEEITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            4957..5628
                     /locus_tag="ACOIAP_002092"
     CDS             4957..5628
                     /locus_tag="ACOIAP_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2638975.1"
                     /translation="MKVLIVEDNKILLESVAEELRKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            5618..6850
                     /locus_tag="ACOIAP_002093"
     CDS             5618..6850
                     /locus_tag="ACOIAP_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2638976.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDAGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKINLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIVLELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSVEINVT
                     SDVDIGTTFELSIPKKLK"
     gene            7006..7323
                     /gene="trxA"
                     /locus_tag="ACOIAP_002094"
     CDS             7006..7323
                     /gene="trxA"
                     /locus_tag="ACOIAP_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGZ2638977.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            7340..8218
                     /locus_tag="ACOIAP_002095"
     CDS             7340..8218
                     /locus_tag="ACOIAP_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGZ2638978.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SVDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKEKHIEVDG
                     VFVIKDSTSPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            8489..8857
                     /locus_tag="ACOIAP_002096"
     CDS             8489..8857
                     /locus_tag="ACOIAP_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGZ2638979.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIRKCCKRREK"
     gene            8860..9231
                     /locus_tag="ACOIAP_002097"
     CDS             8860..9231
                     /locus_tag="ACOIAP_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HGZ2638980.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTTVDAVIVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(9375..9830)
                     /locus_tag="ACOIAP_002098"
     CDS             complement(9375..9830)
                     /locus_tag="ACOIAP_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638981.1"
                     /translation="MNINTVQGDSIEVLLRQLGATKISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(9869..11134)
                     /locus_tag="ACOIAP_002099"
     CDS             complement(9869..11134)
                     /locus_tag="ACOIAP_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HGZ2638982.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNEKAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            11603..13054
                     /locus_tag="ACOIAP_002100"
     CDS             11603..13054
                     /locus_tag="ACOIAP_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGZ2638983.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFSNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLENVSEWHRELPEEHLG"
     gene            complement(13264..13692)
                     /locus_tag="ACOIAP_002101"
     CDS             complement(13264..13692)
                     /locus_tag="ACOIAP_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2638984.1"
                     /translation="MKTYSIQDLTLDKRNLIKKYSLTLNEDLIWEFKHSKYHTIKYFT
                     HKFAVKESVLALLFNIHKLCYAKIKYFESNFSKYEPYKYSYQHGFVKCEMYDMNFILH
                     KYSNIMIDLRNLQEIKTIEEFRLFCDYLESFEDNLQDLII"
     gene            complement(14094..14555)
                     /gene="ribE"
                     /locus_tag="ACOIAP_002102"
     CDS             complement(14094..14555)
                     /gene="ribE"
                     /locus_tag="ACOIAP_002102"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGZ2638985.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVST
                     KNIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDNELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(14661..15854)
                     /locus_tag="ACOIAP_002103"
     CDS             complement(14661..15854)
                     /locus_tag="ACOIAP_002103"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGZ2638986.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDEGRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINGENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRVPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(15877..16542)
                     /locus_tag="ACOIAP_002104"
     CDS             complement(15877..16542)
                     /locus_tag="ACOIAP_002104"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGZ2638987.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTTLLAKNVGDFVNLESDVIGKYVNNFMVNNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(16576..17688)
                     /gene="ribD"
                     /locus_tag="ACOIAP_002105"
     CDS             complement(16576..17688)
                     /gene="ribD"
                     /locus_tag="ACOIAP_002105"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGZ2638988.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDDYI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLRDNNIDVTVGTLEEEARDLNEVFFYYIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESKKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNRLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLAINNVTLIDGDILIESDVLN"
     regulatory      complement(17820..17941)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            18130..20613
                     /gene="recQ"
                     /locus_tag="ACOIAP_002106"
     CDS             18130..20613
                     /gene="recQ"
                     /locus_tag="ACOIAP_002106"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HGZ2638989.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILNEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKAMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFLELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKSLPKRPIVTAFTATASEEVRIDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILNYFGENYMDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFINTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNVLRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFETVIKEYVEKNNINKKINEKNVDLKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPEYMILANKTLKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILEEVNKYVKENDINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHRISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      20702..20813
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            20955..22256
                     /gene="thiC"
                     /locus_tag="ACOIAP_002107"
     CDS             20955..22256
                     /gene="thiC"
                     /locus_tag="ACOIAP_002107"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HGZ2638990.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKVKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            22310..22504
                     /gene="thiS"
                     /locus_tag="ACOIAP_002108"
     CDS             22310..22504
                     /gene="thiS"
                     /locus_tag="ACOIAP_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HGZ2638991.1"
                     /translation="MKVNGKEIEFEENLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            22497..23300
                     /gene="thiF"
                     /locus_tag="ACOIAP_002109"
     CDS             22497..23300
                     /gene="thiF"
                     /locus_tag="ACOIAP_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HGZ2638992.1"
                     /translation="MVKIKIFVNESLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGIKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DVFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            23363..24133
                     /locus_tag="ACOIAP_002110"
     CDS             23363..24133
                     /locus_tag="ACOIAP_002110"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HGZ2638993.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPIQMA
                     RAFKLAVEGGREAYIAKTGSVSEFANASSPLTGFLGNL"
     gene            24150..25253
                     /gene="thiH"
                     /locus_tag="ACOIAP_002111"
     CDS             24150..25253
                     /gene="thiH"
                     /locus_tag="ACOIAP_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HGZ2638994.1"
                     /translation="MSFYDVIEKYRNFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEAMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPYIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            25254..25943
                     /locus_tag="ACOIAP_002112"
     CDS             25254..25943
                     /locus_tag="ACOIAP_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGZ2638995.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELKN
                     LYMKIKTKINCIDFQEQISDESLKTNINQKGCGNKFKVNFIINSNIEFFEKMDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVDEVEYLEKLIRKQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAVMSTIMKSKDIK
                     KTISNYNEKLN"
     gene            26129..27523
                     /locus_tag="ACOIAP_002113"
     CDS             26129..27523
                     /locus_tag="ACOIAP_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGZ2638996.1"
                     /translation="MTDSKKKRFVIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLAGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            28039..29406
                     /locus_tag="ACOIAP_002114"
     CDS             28039..29406
                     /locus_tag="ACOIAP_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGZ2638997.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILSYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIITFICREHECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            29431..30039
                     /locus_tag="ACOIAP_002115"
     CDS             29431..30039
                     /locus_tag="ACOIAP_002115"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HGZ2638998.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHEKLFIEIAIEAFKNFDELIIISNNEELYSKYDIRVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNSEVVERIANKMKDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            30087..30458
                     /locus_tag="ACOIAP_002116"
     CDS             30087..30458
                     /locus_tag="ACOIAP_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGZ2638999.1"
                     /translation="MNLLKCDSWAVILNNSNKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            30616..30954
                     /locus_tag="ACOIAP_002117"
     CDS             30616..30954
                     /locus_tag="ACOIAP_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HGZ2639000.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            31421..31924
                     /locus_tag="ACOIAP_002118"
     CDS             31421..31924
                     /locus_tag="ACOIAP_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HGZ2639001.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNRIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEILRGQVTE
                     CATKKSK"
     gene            31971..32930
                     /gene="moaA"
                     /locus_tag="ACOIAP_002119"
     CDS             31971..32930
                     /gene="moaA"
                     /locus_tag="ACOIAP_002119"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HGZ2639002.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKVRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRILELEKCGLNKVNISLDSLKEYKYKSITRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            32934..33404
                     /gene="moaC"
                     /locus_tag="ACOIAP_002120"
     CDS             32934..33404
                     /gene="moaC"
                     /locus_tag="ACOIAP_002120"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061799 - cyclic pyranopterin
                     monophosphate synthase activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HGZ2639003.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDIDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            33436..33867
                     /locus_tag="ACOIAP_002121"
     CDS             33436..33867
                     /locus_tag="ACOIAP_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HGZ2639004.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENITTEGIEVFSLPIGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVQVLKEGIINVNDSIDVI"
BASE COUNT        13344 a         3636 c         5711 g        11342 t
ORIGIN      
        1 ttttattaaa gttggttaat aattttaaat aaactttaat aaaatacatt aaaatataat
       61 aaattcttct atgctataaa atttatttta tagctattaa atcggatgtt taaaaatttt
      121 ttaagagtct atagtaagga atctaaaatt ataattttac atctgtactt gttcgagaac
      181 tccaagtata aaaaactaag gaattatata gtggcagtat ataattaata cccttagaca
      241 cacctttttg aaagtggaaa aaagatgtgt agttctcctc gaccacaaat caaggaggat
      301 aaaaaatgga aaaaagaaaa gtaataatcg attgtgaccc aggaattgat gattctttgg
      361 caattcttct ggctttaaac tcaccagagc tagaagtaat tggaattacc acgtgctgtg
      421 gaaatgttcc agcaaatata ggtgcagaaa atgcactaaa aacacttcaa atgtgttctt
      481 cactaaatat tccagtatat ataggagaag aagcaccact aaaaagaaaa cttgtaacag
      541 ctcaagatac acatggagaa gatggtattg gagaaaactt ttatcaaaaa gttgtaggag
      601 ctaaagcaaa aaatggagca gtggatttta taataaatac tttacataat catgaaaaag
      661 tatcaataat agcacttgca ccacttacaa acatagctaa agcacttatt aaagatagga
      721 aagcatttga aaatctcgat gagtttgtat ctatgggagg agcatttagg attcatggaa
      781 attgctctcc agtagcagag tttaactatt gggtagaccc acatggagca gattatgttt
      841 acaagaattt atctaaaaaa atccatatgg taggtttaga tgtaaccaga aaaattgtac
      901 ttactcctaa tactattgag tttataaata gacttgataa gaaaatggca aagtatataa
      961 ctgaaataac tagattctat attgatttcc attgggaaca ggagggaata attggctgtg
     1021 tgataaatga ccctttagca gtagcgtatt ttatagatag aagtatatgt aaaggatttg
     1081 aatcatatgt agaagttgta gaagacggga tagctatggg tcagtctata gtagattctt
     1141 tcaatttcta taaaaaaaat cctaatgcaa ttgttctaaa tgaagttgat gagaagaagt
     1201 ttatgtacat gtttttaaag aggcttttta aaggttatga agaccttata gactctgtgg
     1261 aaggagtgat atagtgtgaa aagaaaaata tgtgtaaaaa ctattacact tatagctttt
     1321 ggtatttcca taaatataat aggcgctttt atagctatgg gattaagatt acctgtatat
     1381 ttagattcaa taggaactat aatgatagct tcacttttag gacctaaata cgctgttgtt
     1441 acaggtgtgt ttggaagttt aataagtgga attacgtttg atttgtattc tctatatttt
     1501 gcaccagttc aaatatcaac aggattactt gctggaatag catttaaaaa gaatttttta
     1561 aggggtttaa aaactccact aggagtactc ttatttgcca ttccaacgtc tataataagt
     1621 tcaataattt cagcattttt atttggaggt atgacatctt cgggttcatc ctatatagta
     1681 caaatcttga aagtattagg attgggagat gtttttagtg tgtttgtaac ccaaatattt
     1741 actgattatg cagataagtt gttagcagtt gttttagtga atttaggact aaatgcagtt
     1801 ccaaaaactt taaaggtgtc attgactgga ggaaaataga tataaaatgg atagatatag
     1861 tgaaataaca aataaaaatc aaagagaaat tgttctgctt aaaggatttc cttgtatatg
     1921 gggaaagtgt tctttttgtg attatataga tgataattct aatttagaag aagagatgaa
     1981 taaattaaat ctagaggttt taaaaaatgt aactggaaaa tatggagttc ttgaggtcat
     2041 aaattctgga agttgttttg aattacctaa ggatacttta gaagaaataa agcttattat
     2101 aaaagagaag aatataaaaa aattattttt agaaagtcat tggtcttaca gaaataggct
     2161 tgaggaaatg agagagtatt ttgaaattcc tgtgatattt aaaattggag ttgaaacctt
     2221 tgacaatgac tttagaaata atattttaaa taaaaatgca aattttaaga ctccacaaga
     2281 tgtaaaagac tattttgatt caccttgtat tatggttgga ataaaaggac aaacaaaaga
     2341 gatgatagat aaagatatag agattatctt aaatactttt gaaaaagcga cagtgaatgt
     2401 ttttataaat aattcttcta atataaaaag agatgaagag ttagtgagat ggtttgttag
     2461 taagtataaa ttcttggatg aaaatccaaa tatagaagtt ttatacaata atacagactt
     2521 tggtgtagga gattagcatt aatttagttt aaatttaaaa ttgaaaaatt tcttatgttt
     2581 ttgaaaaagc ttctaatagt tagaagcttt ttttgtagag ttttatgtta caataagaaa
     2641 aaaggaatta aggagcaaat aaatgatgtt taatagggga aaatggaata aattggatta
     2701 taatgaactt ttagaatata tgatgtctat gcaagatata aaacatagag attttaataa
     2761 aaagcttata cctggaacag aaaatataat aggtattaga gttcctaatt tgagaaagtt
     2821 atcaaaagaa ataagcaaag ggaattggca ggaattttta gaagtagcag aggatacata
     2881 ctatgaagaa gttatgctac aagggatgat aattggcaat ataaatagta attttgaaga
     2941 aactttatac tatgtaaaaa gatttatacc taaaattaat aattggtcag tttgtgatgg
     3001 attttgttct ggtttaaagt ctatgaagaa atataaagaa aacatgtatg atatacttaa
     3061 aaaatatgtt tattcagaga atccatggga aattagattt gcattagtta tgtttttaat
     3121 atattatgtt gatgataaac atattaaaga aatatttgaa tactgtaata atatacaaag
     3181 tgaagaatat tatgttaaaa tgggtatggc atggttgcta tcaatttgtt ttattaaata
     3241 tgaagaagaa acttttcttt atataaaaaa taacaattta gatgatttta cttataataa
     3301 aacgctacaa aaaataattg aatcaaatag agtagattta gaaaagaaga atataataag
     3361 aagtatgaaa agaaagacaa gaagatattg acggaggaat attaatgaat aacaatgaag
     3421 aaagaattga caaattttta gaacttcaaa gcaaaggctt tagatttgca gagatagctc
     3481 aaaatctaaa gattagtcaa agtactttaa gaactttttt aaataaaaaa gggtataagt
     3541 cagaaaaagg taaatacata ttaaaagacg aattaaatta taataaaagt ttagataatg
     3601 gagacttgga agaagaaaaa gttaaagagt atgaaaaaag taaaaagaat actataagta
     3661 atagaaaaaa agtaagcacc aaaaaaaagg tttctaatga aaaggtttta agtaaaagta
     3721 ttgaacaaat tgagtttaat gatacaggct taaaaaatgc aaagccaaaa aaaaatgtta
     3781 agcctaagaa agatagaaaa ataaatataa ctcaagaaga tttagataag ctttgtgaag
     3841 tatatgattg gtacttagaa gtaaaagatt acaatatgaa gcctaaaaaa gtatctaata
     3901 aaaaagatat acatatagat gatgaaacca tagatgaatt aaaaacaaca agaatacgta
     3961 tagataagga agtatggaat gattttgaaa gattatgtag taattcaaat tttgaaaaac
     4021 atcaaatact tacacaagca ttgaaagaat ttatgaaaaa atataaaaat ctactataaa
     4081 atactactat atgaggtgct taatatgaat aaaatagtaa aaaaatcaat ttctttaatg
     4141 attatattaa caatatttat ttttacgttg acagcatgtg aaaaagatga acaacctgat
     4201 tcagttgata ttcaagtaga agataaaaaa gagataaaaa tagatgaggg aaatgcaaaa
     4261 gtattgaata taggaaaatc agaaattata aatatggatg aaggtgataa agtagataca
     4321 tccacaaaga tagaaaataa ctcaacattt aatatatcca atgttgaatt gatatataat
     4381 gaatatgatg agaataaaaa aattatatct tcagatagta aggctttgtt ggacatgact
     4441 ttaatgcctg gaaaagttgc ttatatagaa tgtgggcata aaacctttgt aaagagtgta
     4501 gaagtttatg catatgaata tgaggcagag ggtaaaattg tgtatgttaa tttaaaagaa
     4561 aatactattg atataagaaa taataatatt aagctagaaa atagtagtca gtatgaggta
     4621 ctatctacat cagaacttaa aaaagtaaat gaatcaaatg aggaaattac gtatcaagta
     4681 aaagtaaaaa attcatcatc aaaagattta ggaaatatta ttcttaagac agcagaagtt
     4741 aatgaaaatg gagaatattt aacagtaaat cgtgtaccat catataagat tttgaagcct
     4801 tcagaagaga cagatataga tatattgtgc tccacaaagg caaaaagtgt tgaaatagta
     4861 ggatatacat atgatgatat aaaggaaaaa gccaatgtgg atattgactt aaaatctcat
     4921 aaagttaaga tagacaaata aaggtagggg atacttatga aggttttaat agttgaagac
     4981 aataagatac ttctagaaag tgtagcagaa gagcttagaa agcattttga aactgaaaag
     5041 tgtgaagatg gagaagaagc tttatactta gtaaatcaaa atatatatga tttagttatt
     5101 ttagacttaa tgcttcctaa tataaatgga tttgatatcc taaagaaaat gagagttaat
     5161 aatatagata cacctgtact tatattgaca gcaaaagaaa cattagatga caaagtggaa
     5221 gcatttacta taggagctaa tgattattta actaaacctt tttatatgga agagttagta
     5281 gcaagggtgt atgctatatt aaggactaat ggaaagataa aagaaagaaa cggattagaa
     5341 tttaaatctt tatatttaga tacactagaa aaaagagtgt atattgaaaa agaagaaata
     5401 aaacttcaaa acaaacagtt taacttgctt gagtattttg tactaaataa aggttcaatt
     5461 ttattaaaag agcagattta tgatagaata tggggaattg attcagatgc aactattgaa
     5521 atagtggaag tatatgtaag taatctaaga aaaaagctca gtaaatatgg atatgataaa
     5581 tatattaaaa ctaaacgtaa ggtaggatat atattcgatg ataaataaga atgtatttac
     5641 tagtactaaa aatcatctaa taaaaatgta tattattgta gtaggtagtt ttttaataat
     5701 cttttctata tttatatatt catattttag gggacttaca tatagtggaa ttgatagtga
     5761 gataaatgat gagcttgaat atatagtttc tcaatttaaa agaacttcat ttttgaaccc
     5821 aataagactc aaagacccta aagatatggt gtatgtatat gaagatggaa ggataagtta
     5881 ctatactcaa aatgaatatt ttgatgagtt gcttccagat agaagactag ataaaaaaaa
     5941 ttcgtttttt aaatacacag aaaatggata tactttcaga gaattaaatg tagatgcagg
     6001 tagataccaa atacagataa ttagaaatat agattctgag atgaattctt taagacagct
     6061 tacatctgtt cttataattg gaatattaat ttctgtaata attacttact ttgtagctgt
     6121 atatctcact agaaaagctt taattccaat agaaacagca tggaaaaatc aagctaagtt
     6181 tatacaagat gcttctcatg aattaagaac accaataaca atagtttcat caaaattaga
     6241 aagtatgtta aaatccccag aaagtacagt aaatgatgaa gttgaaacaa tagctactgc
     6301 aatgaaggaa actaggagac ttaaaaaaat gataactgat ttattgtctc ttactaaaga
     6361 ggattctatt gttaaaatta atttagaaga aatagactta gaaaagttat tggaagaaat
     6421 atcagaagac tatattgaca tagctgaatt tcaggaaaaa agattcgtat ttaattctaa
     6481 actgaagaat aaagttataa taacagataa aaataaatta agacagctta tattgatttt
     6541 tattgataat gcctttaaat atacaaaatt gggagatgag atagtattag aattaaaaga
     6601 agatatagaa gatgaggtaa ctttgcttat aagtgatact ggtataggta taaaaaaaga
     6661 agaaatacct cttatatttg atagattttt tagaagtgaa aatgtaagaa ataaagattt
     6721 agaaggttct ggaataggac tttcaatagc tcgaatgatt agcttaaact tgtctgttga
     6781 gataaatgta acttctgatg tagatattgg aactacattt gaattatcaa taccaaaaaa
     6841 gttaaaataa taaaaatata aaaagttgtt tttagaaata aagaatgggt atactaatta
     6901 gtataaaata aaaaataaaa agaccttata aaagtaaaat tatatttata aatttcatag
     6961 tataattata tagggataat aaagtttaat aggaggattt aaaaaatggc aaaagttata
     7021 aatacatctg aatttagaag tagtgttgaa ggtagtaagg gagtagttgt agttgatttc
     7081 tttgcaactt ggtgtggacc ttgtaacatg ttgggacctg tatttgcaga attaggtgaa
     7141 gagatgaaag ataaagctag atttgtaaaa gttgatatag atgagagctt agaaatagct
     7201 caacaattca atgtgtctac agtaccaact atgattatat ttaaagatgg aaaaccagta
     7261 gaaactttaa ttggattcat gccaaagaac aaaattgaaa tgcaagtaaa atcatattta
     7321 taaaaaatgg gtgagtatta tgagatatga tatagctata attggtagtg gtccagctgg
     7381 attgtctgct gctataaatg caaaaataag aaataaaaca attatcatgt ttggtaatga
     7441 taatttaagt aataagcttg ttaaagcccc ttcagtagat aattatttag gtttttatga
     7501 tataagtggt gatgaattaa aagataagtt taaatcacat atagatagta tggatatttc
     7561 aattgaaaat aaaagaataa ataatattta tgctatggga gaatacttta caataatgtc
     7621 tggaaatgat atgtatgagg ctactactgt aatccttgca actggagtag agtatactag
     7681 accaatcaag ggtgaagaag aatttctagg aagaggtgta ggctattgtg ctacatgtga
     7741 tgcaccactt tatagaaata aaaaagtagc agttatagga tataatgaag aatctaaaga
     7801 agaagcaaat tttttaagtg aactcacttc aaagacttat tttataccta tgtacaaaaa
     7861 agataatctt atgagaagtt cagataacct agatgattct attgaagtca tacatgacag
     7921 accagtacaa atagatggag ataaacttgt aaacaaagta tcttttaaag aaaaacacat
     7981 tgaagttgat ggagtattcg ttataaaaga tagtacatct ccaagtgcct tggttcctgg
     8041 aatagaaatt gatggcattc atattaaagt tgacaataat atgaaaacta gtatagatgg
     8101 atgttttgct gctggagatt gtgttggaaa accatattct tatataaaag cagctggcca
     8161 agggcaaata gcagctttaa atgctgttta ctatttagat aaattaaaga gggcttaata
     8221 tttatattga ttaacttttt aaagatattt ataaaaaact gtcttgaaat aattttatta
     8281 tttcaagaca gttttttatt tgtaaattac tattaaaagt attttaaaat ctatatgtaa
     8341 ttacttttat taaaaaaaat taaaagttat attagaaaga attagaatta tttataatat
     8401 ataccaaaat ttaaaaataa tggttgaaaa atctaattaa gagtactata atttaattaa
     8461 gtaattactt aatcaaaacg aggtacttat ggaaaacttg gttaaaatat ttaaagcatt
     8521 gagtgatgaa actagactta acatacttat attagtatcc aagagaaata tatgtcaaaa
     8581 ggggatttct aaatatctag ggatttcaga ttctgctgtt tcacaacata taaaaatatt
     8641 aaaagatgtt gggataataa caggatataa agaaggatac tatgttttat atcatattaa
     8701 taaagaatca tttaatatat gtgtagattt tataaattct atgttaagta attctagtga
     8761 aagctttata gatgtatttg atgtaaatac aatacatcta ggatgcagta aagaatgtaa
     8821 atctataaga aaatgttgta agagaaggga gaaataataa tgaaagtatg tataccagta
     8881 gaagagaata agggattgga tagcaaacca tatgggcatt ttggttctgc tccaattttt
     8941 gttgtgtgtg atttagaaag tggagaagtt aagtctttag ataatggcga tttagatcat
     9001 gaacatggaa aatgccaacc attaaaagca ttgtcaggta caactgtaga tgcagtaata
     9061 gttggaggaa taggacaagg agctataatt aaattaaatg gaatgggaat aaaagtttac
     9121 agagccgaag gcgatactat aagtgctaat ttagacctac ttaaaaatgg aaaattagta
     9181 gagtttccat cagaccatac ttgttcacat gatggatgtg gacatcatta aaaaaaatag
     9241 ctgatgaaac atatgcttca tcagctattt tttcttttaa taaatacgat tttattcttt
     9301 taaaaccaaa atttagattt ttatgttttt tgtaatatcc tcgataacat ctcgagttta
     9361 taagtttact acttttagat ttttttcgta tgtttttcta tatagtcaat atcatttaat
     9421 atgtcattaa gctctttatt aagtgttttt aaatcatcac catctacatt gtagtttaaa
     9481 aatagttctt ctacattatc aatgatagaa ttaacttttc tagtaacttc aacaaatgtt
     9541 ttaaagttac tactattttt agcatttaga aattttttta aatcctttga tataaatgat
     9601 actatttcat attcgtcatt aaatagacct ctaccaatag gatatggttc aattctctgt
     9661 aaaaaatatt ggtctttagc attaatatta taagtataag atatttccca accgtctcct
     9721 aaatcaaact taataaaata taatgtacta cttacttttg atatttttgt agcaccaagt
     9781 tgtcttaaaa gaacttcaat cgaatcacct tgaacagtat taatattcat atatacacat
     9841 cccctttagt attattatac tatatttttt aaaattttat aattaaataa acagtagata
     9901 taataataga tataatcata agtggaaaac ctattttgaa atactcttta aaagagatag
     9961 gatgcccgtg tttattacct atacctgcta gtacaacatt agcagatgct cctattagtg
    10021 ttccatttcc tccaagacaa gctccaagag atgttgccca ccatagtggc attacatcaa
    10081 taccttcagc ttgcatagtt aaaataagtg gaattagtgt tgcaacaaat ggaatattat
    10141 ctaagaaaga agagactatc gctgataacc atagtatcaa caacattgta aatacaagat
    10201 gtccttctgt aagtccaatc aatgcctgag ccaatttatt tattatacca acttctacta
    10261 atccaccaac tactacaaat aatcccataa agaataaaat tgtagaccat tcaatacctg
    10321 ccataatttc atctacatcc tgttttccta ttagaagcat tatagatgct cctgtcagtg
    10381 ctacaacaga agagtctata tggattgtac tgtgaaacat aaaaccaaaa agtatgaatg
    10441 ctattaatat aagacttttt ataagtagag gtttatcttt aacagatttt ttttcatcga
    10501 gtttcaatat tgcgttttta gctttttcat ttacaacaag ttcttttcca taaataaatc
    10561 taaagcatat tatagttata gcaagtatta ctataacagc aggacctaaa tttattacaa
    10621 aatccataaa actaagattg gcagcactac caatcataat atttggaggg tctcctataa
    10681 gagtagctgt tcctcctata tttgaagcta aaatctgtgt tattaaaaat ggaacaggat
    10741 taagtcctaa tatttgtgta ataactatag tcattggtcc aataagtaag acagttgtaa
    10801 cattatctaa tacagctgat aaaatagctg ttataatagc aaaacaaatc attatcttcc
    10861 atgggtcacc tttagctttc tttgcagtcc agatagctat gtattcaaat aatcctgagt
    10921 ttttgacaac agctacaaat agcatcatac caactaatac accaatagtg ttgaaatcta
    10981 tatggcttaa tccttcatca agcgtaagta tattgaatat tatcattaat agtgcaccac
    11041 caacagctgc tacggatctg tttacctttt ctgtaataat agctgccata actattaaaa
    11101 atatacatat agctattatt tgttgaaatt ccataatata agtacctcca tttgtattat
    11161 tttgagccta atgctagtac tatatatagt attacttttt tattgttttt tcaatggatg
    11221 tatgaaagta tattatttaa caaagttttt gaaaaattga cagaatttaa agaaaatttt
    11281 tgttatttaa ataaatttta aaatcattcc attgataata atattaaacg acaaacgaaa
    11341 aaatataccc ttcaaactag aatttattgt aacaaataac aattataaaa tattaaatat
    11401 atctatatta taaaaacagt aaaaaaaggt ttaatctgaa tataaaactg caatatatta
    11461 aaaaaattat tcattttaag ccttgtaatt tgattttata aatattataa ttaaattaat
    11521 gaatttttaa caaggaatta ttcatttttt tgattttaag atttattgag aaaacaaaac
    11581 taaatagggg gtaattaatc taatggattt tttcaatggt attttaacta gtatcaataa
    11641 tgcagtagta tttgtaaaca attacttatg gtcgtatatc ctaattataa tgttagttgt
    11701 aattggtatt tactttacta tcaaaacaaa ttttgtacaa ttcagatatt ttatagaaat
    11761 gtttagactt ctgggtgatg gtacagcaaa taaaaatgca aaaaaggaag gaaaaatatc
    11821 ttcattccaa gcattttgta taagtacatc ttcaagagtt ggaactggaa atatagctgg
    11881 aatagcaatt gcagttgtag caggaggtcc tggtgctgta ttttggatgt ggcttatagc
    11941 attgattggt tctgcatcaa gctttgttga gagtacatta gctcaaattt ataaagttaa
    12001 agatggtcaa gcttttagag gtggaccagc gtattatatg gaacaaggtc taaataaaaa
    12061 atggatgggt attttattct caatacttat aactatatgt tacggttttg tatttaatgc
    12121 agttcaagca aatactgttt cacttgcatt tagtaatgca tttggaataa gtaaaatggc
    12181 catgggaata ggtcttggaa ttttaactgc aatagttatt tttggtggag tgcatagagt
    12241 tgcaaaagtc tctgaaataa tagttcctgt atttgcagga ttatatatat tagttgcttt
    12301 agctatagtt gtaatgaata taacagagat accaagtgtt atagcgttga tagtggaaag
    12361 tgcatttgat tttaaaggaa tggcaattgg tacatttatg ggagttgtaa tgactggagt
    12421 gaagagaggt ctattttcta atgaagcagg tatgggtagt gctcctaatg ctgctgcaac
    12481 agcacatgta actcatcctg taaaacaagg tctaattcaa tctttgggtg tttttacaga
    12541 tactataata atatgtagtt gtacagcatt catggtatta ttatattcag gttatagtag
    12601 tagtggagca actggaattg aattagctca agaagcttta acacatcata taggaccagt
    12661 tggaaatata tttatagcag tttgtatatt cttgtttgcg tttagctcta ttgttggtaa
    12721 ttactattat ggtgaatcaa acatggagtt tatgagtgga agtaagacta aacttaatgt
    12781 atttagagtt tttgttgtag gtatggtttt atttggttca cttactcaag tagatgtagt
    12841 ttggaacctt gcagacttat ttatggcatt gatggcgata ataaacttaa tagcaatagc
    12901 acttttagga aaatatgcat ttattgcttt aaaagattat acaagtcaaa aaaaatcagg
    12961 aataaaagac cctgtattta ttgcagatga aatagaaggt ctagaaaatg tatcagaatg
    13021 gcatagagaa ttacctgagg aacatttagg ataaaaaaat agtataaaat tatgaaatca
    13081 ttttgaaaga ttagagtatg gatatacttt acatgaatat agtattgaat taatttatat
    13141 tactggaact tttaattcca gtaatatttt tttattatgt aatttaactt tattaaaagt
    13201 tttttatcat tgaagataga ttgtatatta taaattttat ctttgggttt cttcttaaaa
    13261 atattatata attaaatcct gtaaattatc ttcaaagctt tcgaggtaat cacaaaataa
    13321 tctaaactct tctatagttt taatttcttg taaatttctc aaatctatca ttatattact
    13381 atatttgtgt aagataaaat tcatatcata catttcacat ttgacaaatc catgttgata
    13441 actatattta taaggttcat attttgaaaa attcgactca aaatatttta ttttagcata
    13501 gcacaattta tgtatattaa acaagagtgc aagaacagat tccttaactg caaatttgtg
    13561 tgtgaagtat tttatagtgt gatatttact atgtttaaac tcccaaatta aatcctcatt
    13621 taaagtaaga gaatattttt ttataagatt acgcttatct agtgttaaat cttgtattga
    13681 atatgttttc atagtttatt ctcctcataa atatctaata agtattaagc aatagtattt
    13741 tattattaat tactcttaat tatattttat ggtaaattaa aaaagtaata aaatagataa
    13801 ttagtatact attagtctgt tctataaata aaaacaatag cttaaatact aatatgctta
    13861 cttttatggt attttatgtt tggaattata tttgtaatta ctgtaagatt ttcaaagtag
    13921 atttgatgga taatgtataa ttttagaaag ggatgtaaat tgttttgtga gatttatata
    13981 catgattata ttaaaaatac taagtatcaa aagaagaaat atagcttctc tctttggtac
    14041 ttagtatttt atatctttta cactaatttt taatatttaa ttaataatat tatttaattt
    14101 agagacttaa ataaatttgc catttctaat gcattcatag cacaatcata acctttattt
    14161 ccagcttttg taccagctct ttcaatagct tgttcaatat tttctgtagt tacaattcca
    14221 aatataactg gtaattcatt gtctaaagat acttttgcta tccctttaga gacttcacta
    14281 catacataat cataatgaga agtagctcct cttataacac atcctaaaca gattatagca
    14341 tcatacttac cacttttagc cattttttga gcaacaagag gaatctcaaa agctccaggt
    14401 acccaaacta tttctatgtt ttttgtagaa acatcgtgtc ttaaaaggca atcttcagct
    14461 cctgataaaa gttttgatgt tataaattca ttaaaacgag aatttattat acctattttt
    14521 aaatcttttc caataagttt tccttcatat atcattttta tttcctccaa ttttatttat
    14581 gttatagatt taaatttata aatatcttta agtttaatta taaaaaatta cttagtagaa
    14641 aaatatccgc atataatcgc ttatataata tctaaaagat gtcccatttt atctttctta
    14701 gtttttagat atagcttatt aaagtcatta atttcttcat taatagggac tctattttcg
    14761 atttttattc catatttctc taattgattt attttatcag ggttattact taaaagattt
    14821 atacttttta tgtttaaatt ttttaatatt tgagcagcca tatagaaatc tctcatatct
    14881 tcttcaaatc caagcattaa atttgcttca acagtatcat aaccttcttc ttgaagttta
    14941 taagctttaa ttttatttaa aagaccaata cctctacctt cttgcttcat ataaattaaa
    15001 actccacttc cattttctac aattttcttc atagaagatt ctaattgtaa tccacaatca
    15061 cattttaaag agtgaaacac atctcctgtt aaacattcag aatgaagtct aactagagta
    15121 ttttctccat ttatatttcc ataagtaaga gcaatatgtt cttcatttga ataagtgtct
    15181 ctatatccta tgatttcaaa gtttccatat tttgttggaa ggaaagcact agatactttc
    15241 tctatagtag tttcatttat tttgcggtat tctataaggt cttttatagt gatgattttt
    15301 aaattatgct tttctttgaa aatcatcaaa tcatcaactc ttgccattgt accatcatct
    15361 ttcattattt cacatataag accaatctct ttaaaacctg caagtctagc aaggtctact
    15421 gaagcttctg tatgtccatc cctaacaaga actccaccag tttttgcgat taaaggaaag
    15481 atgtgaccag gagttttaaa atctttactt gtagaatttt cgtcacagaa caattttaca
    15541 gtttcagctc tttcatatgc agatatacca gtcagagtat ctgccccatc tatagtaaca
    15601 gtaaaggctg tttggaatgt atctgtattt tctctaacca taagaggtat attaaggctt
    15661 ttaaattttt tttcagtagc aggtagacaa attagacctc taccatatgt agccataaaa
    15721 tttattgatt caggagtagc catttcagct gccatcaata aatctccttc attctctcta
    15781 ccttcatcat caactacgat taccattttc ccatttttta tatcttcaat agcttcttca
    15841 atagtattaa acatgtaatt cactccttta ttatttttaa aaaccatttt taaataaaaa
    15901 atctttatct atatttgatt tatggttact actattagaa tttaattcct tgtagttatt
    15961 aaccataaaa ttattaacat acttcccaat tacatcactt tctaaattaa cgaaatctcc
    16021 aacattcttt gccaagagag tagtgttaat tttagtatga ggtataatag aaaccttaaa
    16081 tatttcatca tctaaatatg atatagttaa acttacacca tcaatagcaa cagaaccttt
    16141 aagtatcatt gatgataaaa gttttttatc aggtcgtata ctcactaaaa ctgcattttc
    16201 atctttttca aatttacaga tagttccttt accatcaaca tgacctgtta ctatatgacc
    16261 accaaatctc gaagaaagac tcatagctct ttcaagattt accttgtcat ttgcatttaa
    16321 taaacctaaa tttgtggaac gaattgtctc catcataaca tcagctgtaa attcattttt
    16381 tccgagattt gaaacagtta gacaaactcc atttacagct atactatctc caagatttgt
    16441 gccatctaat attttatttg atagtatggt tacttttcca ctcttaccat tagcagtaat
    16501 ttttctaagt attccaactt cttctactat gccagtaaac atcctgacct cctatataca
    16561 tgtattaata aaaatttaat ttaaaacatc tgattctata agaatatctc catctatcaa
    16621 agttacatta ttgattgcta gctgtgttga atctgacaaa tgatttattc cttctccaga
    16681 aacgaatgta ggtgcatctt taccacctat aatcttgggg gatagaaata atttaacctt
    16741 atcaactagt ctatttctaa agagactgtc attaagtgta gcaccacctt caactagaac
    16801 agaatcaatg tttaattctc ctaatttata cattacaaat tccaaatcta ctaagttatt
    16861 ttttgaagga gaaattattg tttcaacatt attttctttt aacatagata attttttact
    16921 ttctttgcaa catgtgaaaa ctatagtttt actggtttta tctttaacca aattactatt
    16981 aagtggcaac tttaggtgtg tatctattac tattcttgta ggatgagata ctttttcttg
    17041 attaagtcta caagttagta agggattatc gttcaaaact gtatttatgc caaccattat
    17101 actttggtat ttatttctgt atttatgagt taggtatctt gatgattcat tagatatcca
    17161 ctttgattct agtgattttg tagcaatttt accatctaga cttactgctg attttacaat
    17221 gcaaagaggt cttttgtttt ttatataata aaaaaatact tcattcaaat ctcttgcttc
    17281 ttcttctaat gttcctacag taacatcaat attattatct cttaattttt ttactccatt
    17341 accacaaaca agtggatttg ggtctaatgt agatatgaca actcttttaa tcttattttg
    17401 aataatttta tcaacacaag gaggcgtttt tccataatga gaacatggtt ctaaatttac
    17461 ataaagagta gagtctttta gactttgttt agcactgttt atagcattta cttcagcatg
    17521 attagagcca aatttctcat gatatccttt acctattatg taatcatctt taacaattac
    17581 acatccaact aatggatttg gatttacaaa gccttctcca tttttagcca attcaatagc
    17641 ttttttcata taataaatat ctttttcttt ttgattcaca aaattcacaa tatgtacacc
    17701 tcctgtttaa ttggataatt tttaaacaaa aaaccccgag aattaactca gggtttagaa
    17761 taatctagaa taaatgttta ataaatgtac aacaaaattg ctctacaaaa acactcatta
    17821 aatatcttct tccatccaga ctttactgtc ggctttggaa tttaaccaaa tcaaccaagt
    17881 tttacattgg ctcgcgggct ataccgccga ttgggaattt caccctaccc cgaagattaa
    17941 gtattaaatt tatatttaga atgtatcata aattatttta ctttgcaaac tatttttttt
    18001 aaaaatatat gttaatatat aatatagaat gtctataaac tttgaaatac cacgattgtg
    18061 aatataaaaa taaaaatttg aacataatca ggaaagaagt ctaattaatt taaattagga
    18121 gagtaatata tgaataaaaa acttttagaa atactatcaa aatattatgg atatacaagt
    18181 tttagaaaag gtcaggaatc tataataaat tctatcttaa acgaaaaaga tgtattagct
    18241 attatgccaa caggaggggg aaaatcaata tgttatcaga ttccagcttt gattttagat
    18301 ggaatgacaa tagtaatttc tccacttata tctcttatga aagaccaagt agatgcatta
    18361 aaagctatgg gaattagtgc tgcttttata aatagttcat taagtagcaa agaatttaat
    18421 gaaatattaa acaatattag aaaaaataat tataaaatac tctatattgc tccagagaga
    18481 ttagatgcac aggagtttct tgagctaata aataataaca atgtaagtca agttgcaata
    18541 gacgaagcac attgtgtatc tcaatgggga catgatttta ggttgagtta tagaaggatt
    18601 tctgatttta taaaaagttt gcctaaaaga cctatagtta cagcatttac tgcaacagct
    18661 tcagaagagg taagaattga tataataaat ttactgtgtt tagaaaaccc agattattat
    18721 ataactggat ttgatagaga gaatttatcg ataaatatag taaaatcatc tagtaaaaat
    18781 aagtatattt tagattatat tcaaaaccat aaaaatgagt ctggaattat atatgttgca
    18841 actaggaagg aagttgaaaa tatatataat ggtttatcta agagaaatat ttctgtgtca
    18901 aaatatcatg caggtctatc taaaaacgaa agaagtaaaa atcaagaaga ctttataaat
    18961 gataatgtgg atataatggt agcaacaaat gcatttggaa tgggtattga taaacctaat
    19021 ataagatggg ttatacatta caatatgcct caaagtatag aaaattacta tcaagaaata
    19081 ggtagagctg gtagggatgg agaaaaaagt gagtgtgtac ttttattttc tccaggagat
    19141 gtacatatac aaaaatattt aattgatatt ggagttgaaa atcctgaaag aaaattattt
    19201 cagcataaga agcttcaata tatgattgac ttagtttaca gtaattcatg ctatagaaag
    19261 acaatattga attattttgg agaaaattat atggacaatt gcaataattg tagtaattgt
    19321 ttagtagagg gtgaaatagt agataaaact atagatgcac aaaaagtcat ttcatgtgta
    19381 gctagaatga aaaggagtta tggtgttact actattgtag atgtacttag aggttctaaa
    19441 aataaaaaga ttttacagct tggactaaat actttgtcta catataatat tatgagagat
    19501 tattctagtg aagatttaaa gaattttata aatacattag tatctcatgg ttttttagat
    19561 ttagttgaga ctctaggtaa tggaaataga ggtagttttc caactataag attaaatgaa
    19621 atgtctatga aagtgttaaa aggtgaagtg aaagtagaat ttaaagagat tgtgatgaca
    19681 aaatcattgg aagtagaaga tgagttatat aatgttttaa gagaacttag acattcaatt
    19741 gcaagtgaag aaaggatagc tccatatatg gtatttggag atggcacgct tagagccatg
    19801 tctagtagtt atccaattaa taaagaagaa atgctagata tctctggagt aggagaaatt
    19861 aaatatcaaa aatatggtag agattttgaa acagtaatta aagaatatgt cgaaaaaaat
    19921 aatataaata aaaaaataaa tgaaaaaaat gtcgatttaa aaaacgttaa tagtgatttc
    19981 ctagaggtta atacagataa agttctatat gaaaaactgt tagtcattag agaggaatat
    20041 gcaacgaagg aaaaattacc tgaatatatg attttagcta ataagacttt gaaagaaata
    20101 agtggaaggt atccacttga tgaagaacaa ttaaaagata tttctggaat aggtggggta
    20161 aagtttgaaa agtatggagc tagtatttta gaagaggtta ataaatatgt aaaagaaaat
    20221 gatattaatg ttatttggga gaaaaagggg aaaaggaagt taatattaga tggagaaagt
    20281 agaaaaaata atgaaatagc cttagattta ctgaatcaag gaaaagacat acaaagtata
    20341 agtcaagaaa tagaagtttc actgtcaacc attattggat atgtgcatga ctatgtaaag
    20401 gatggacata gaatatcatt tgaattaggg ttagaaaatt tttataatga agataaaaag
    20461 aagatgattt tagaagtttg cgaaaaagta ggttatgata atttaaataa cataaaaaga
    20521 aaacttccag attcaataaa gtatgaaaat ataagagctg tgatacttga ctcttatctt
    20581 gaaaacttaa aaaataatat tatagcagag taatttttaa cttaataaaa aataaaattt
    20641 gtattattat gttgaactaa tatttttgct gtgttatact gaatttgtaa aaataatgaa
    20701 aaattagagc taggggcgct agaattggct agctgagaga taaagccgta acttacaaac
    20761 cctaataacc tgatcaagat aatgcttgcg aagggaagct ttttaatata attttattat
    20821 ataaataggc aaattattta atgttagggt aaatttgtct aagtgtatat acgattataa
    20881 gagtgctttc caaacaagga aaagcacttt ttttattttc aaaaactata actttaatct
    20941 tggaggattg taatatgaac tatacaacac aaatggatgc tgctagaaaa ggcataataa
    21001 ctaaagaaat ggaaatcgtt tctcaaaaag aacaggtaga tgtaaatgaa ttaagagaat
    21061 taatagcaaa tggacaagtt gttataccag ccaataaaaa tcataaatct ttaagtgcag
    21121 aaggtgtagg taaaaattta agaacaaaaa taaatgtaaa tctaggaatt tcaagagact
    21181 gtaaggatat agaaaaagaa cttgaaaagg ttagagtagc aatagacatg aaagctgaag
    21241 ctataatgga tttaagtaat tatggtaaaa ctagagaatt tagagaaaaa gttgttgaaa
    21301 tgtcacctgc aatgataggt tcagtaccta tgtatgatgc agtaggatat ttggaaaaag
    21361 aattaaaaga tataacagaa gaagagtttt taaatgtaat aagacaacat gctattgatg
    21421 gagtagactt tattactata catgcaggtc ttacaagaag tgtttgccaa aaagtaaaaa
    21481 atcatgagcg attaactcat atagtatctc gtggaggttc tttattgttt gcatggatgg
    21541 aattaaataa taaggaaaat cctatttata ctaattttga taaaatattg gatatatgtg
    21601 aggaatatga tgttacattg agtttaggag atgcttgtag accaggttgt ataaaagatt
    21661 ctactgacgg tgttcaaatt caagaacttg tagtattagg tgaacttact aaaagagcct
    21721 gggaaagaaa tgtacaagta atgatagaag gtcctggaca catggctatt gatgaaatag
    21781 aagcaaatgt agtattagaa aagagattat gccatggagc acctttttat gttcttggac
    21841 cattagttac agatatagca ccaggttatg accatataac aagtgcaata ggaggagctt
    21901 tagcatgtgc taaaggagtg gattttttat gttatgtaac tccagcagag catttaagac
    21961 tgcctaattt agatgatatg aaagaaggta taatagctgc aaagatagct gctcatgcag
    22021 gagatatagc taaaaatgtt aaaggtgctc gtgaatggga taataagatg agtaaagcta
    22081 gagctgattt agactggtgc gagatgttta ggcttgcaat agaccctgaa aaggctaaga
    22141 gatacagaga tgaatcaact cctactcatg aagatagttg tactatgtgt ggaaaaatgt
    22201 gctcaatgag aacggttaag aaaatattaa acaatgagga acttaattta atataattgt
    22261 tggatagtat gactaaagta aaaagaagtt gaaaagagga ggtgatttag tgaaagttaa
    22321 tggtaaggaa attgaatttg aagaaaattt gactgttata gatttattaa ataaatataa
    22381 tttaaagagt gatagagttg tagttgaagt gaatttagag ataattgaag aatctaacta
    22441 caatacatat gtattaaaag acgaggatat tgtagagctt attagcttta ttggaggtgg
    22501 ttaaaataaa aatatttgta aatgaatcat taacagatgt tgaggaaaat acaactgctt
    22561 ataaagttag agatagctat aacaataaat gtgatgtatt agtgttaaat ggatatccaa
    22621 ttaaaacaga tatgcccctt tgtgaaaatg ataaattaac acttatacaa aaaggcatta
    22681 agccatcact tgatgagttg gaaagtttgc tgattgctag acatactcca aatatacata
    22741 ataagttaaa aaaagggaag gttgctatat tgggattggg aggacttggt tccaatatag
    22801 ctatctcttt agctagaatt ggagtgggag aacttttact tatagattat gatgttgtag
    22861 aaccatctaa cttgaataga caacagtatt ttatagatga tataggaaaa ctaaaaactg
    22921 atgccatgat agaaaacata aaaaaaataa atccttttat aaaattaaat aaacgagatg
    22981 tttttttaaa caaaaataat atggacacta ttaaagactc agatttaata attgaggcat
    23041 ttgatgatgc ttcatgtaag gcacaggtat gtaattatgt attaataaat ttaaaagata
    23101 aatatctaat agcatcatct ggtatggcag gttattatga ttcaaatata ataactacta
    23161 agaagataaa agacaggttt tatatatgtg gggactttgt gaatgaagct aaatttggtg
    23221 aaggacttat ggctccaagg gttgctatct gtgcaaatca tatggcaaat ttggcaacac
    23281 aaatacttat agatatgtaa atattaaaat tagacactaa aaagattgaa tattaaaaaa
    23341 atttaatatg gagggaaata atatggataa attggtactt ggtggacatg aatttaatag
    23401 cagattattg gttggaacag gtaaatatgg ttcaaataat atattgcctg aggtaataaa
    23461 agaaagtgga agtgaaataa taacaatggc acttagaaga gtggatttag acaataagca
    23521 agaaaacata ttaacatata ttccaaaaga aatgacaata cttccaaata catcaggagc
    23581 tactaatgca gaagaagctg taagaatagc tagaatatct agaaaaatgg gatgtggaga
    23641 ttttataaaa atagaagtaa tatcagatac tagatatcta cttcctgata atgaagaaac
    23701 tataaaggct acaaagatac ttgctgatga ggggtttata gttcttccgt atatgacacc
    23761 agacctttat gctggaagaa ggcttataga agctaatgca gcagcagtta tgccacttgg
    23821 agctccaatt ggttcaaata gaggtcttca aatgaaagag atgataagaa taatgataga
    23881 tgagttggat ataccaataa tagtagatgc aggtattgga aaaccatctc aagctatgga
    23941 ggctatggaa atgggagctg atgcagtact tgtcaatact gctatagctt cagcaggaga
    24001 ccctatacaa atggctagag catttaaatt agctgtagaa ggtggaagag aagcatatat
    24061 cgcaaaaaca ggaagtgtgt cagaatttgc aaatgcttct tctcctttaa caggtttttt
    24121 aggcaattta tagaaagtgg tgattggtga tgagttttta tgatgtaata gaaaaatata
    24181 ggaattttga ttttgatgga tatttaaata atgttactga taatgatgtt ttaagaagtt
    24241 tatcaaaaga caagcttgag gattttgata tattaaattt gctttctaaa actgcagtaa
    24301 aacatttaga agccatggca caaaaagcac ataaattaag tgttcaatac tttggtaaaa
    24361 cagtatgttt atatacgcca atgtatatag caaattattg tgttaatcaa tgtgtttatt
    24421 gtagctataa tataaaaagt ggaataaaaa gaaaaaaatt aaccatggat gaaattagag
    24481 aagagggaga agcaatttca aaagaaggtt ttaaacatct acttgtcttg actggagaaa
    24541 gtagttttca ctcaagtgta gaatatatag gtgaggctat agaaatatta agagaaaaat
    24601 ttccctctat agggatagaa gtttatccaa tggaagtaga agaatataag tacattgtag
    24661 ataaaggtgt tgaaggacta acagtatatc aagaaactta tgacgaggaa atatataaga
    24721 gagtacatat aaaagggcca aaatcaaatt ataaatttag actagatgct cctgaaagag
    24781 gggcaaaagc aggtatgagg actttatcaa taggtgcact tttaggatta aatgatttta
    24841 gaaaagaaac tttttttaca atattgcatg ggaaatactt aaaaacaaaa tatccttata
    24901 ttgagctttc atattcaaca ccaagaatga gaccttttaa aggttgtttt gaggaattgg
    24961 tagatataag tgatactgat ttagttcaag ctatggtatg tatgagatta tttgaccctc
    25021 atgcagctat aaatatatca actagagaaa atttagaaat gagaagtcat ataatacctt
    25081 tgggagtaac taaattgagt gcaggtgtat ctactgatgt aggaggtcat tctcaagatg
    25141 aacatgatac agctcaattt aagataaatg atgaaagtac tgttaaagat gtggagaaaa
    25201 tgctaaactc aattggttat cagcatgtgt ttaaagattg ggaaagattt taaatgtatt
    25261 tgataacaaa cagaaagtta tgtagtgaag aacgatattt agaagttatt aaagagtcta
    25321 tattgagtgg tgtagaaaat atcataataa gagaaaagga tttagaatat caagagctaa
    25381 aaaatttata tatgaaaata aaaactaaaa tcaattgtat agattttcaa gagcaaatat
    25441 cagatgaaag tttgaaaact aatataaatc aaaaagggtg tggaaataaa ttcaaggtta
    25501 attttataat aaatagtaac attgaatttt ttgaaaaaat ggattgtcaa ggtatccatc
    25561 ttccttttaa attattcttg aatttaattg aaaataagta taattttaat gaaaataaaa
    25621 tactaggatt atctttacac aaagtagatg aagtagaata tttagaaaaa ttaataagaa
    25681 agcaaaatat aaaaatagat tacataacat tatcacatat atatgaaact aaatgtaaag
    25741 aaggattaaa tccaaaagga attgagcttt taaaagaagc taaaaagatt actgatatta
    25801 aaataattgc acttggggga attttaccat ctaatgtcaa agaaacatta aaatactgtg
    25861 atgattttgc tgtaatgtcg actataatga agtctaaaga tattaaaaaa accatatcaa
    25921 attataatga aaagttaaat tagtaaatat agtatgttga atttttaact taaataaaaa
    25981 taagaaagct atcttttaaa ttttaaaagg tagcttttta ttttgtatct ttgctaataa
    26041 aaaattgtaa aaagggaaaa ctttagtcag agagattaac aatatcctag aaagatttaa
    26101 aatttagtaa agtatggagg acattataat gactgacagt aaaaagaaac gatttgttat
    26161 accacacact tttacaataa tatttttact aatagtctta atggcaatat tgacttggat
    26221 agtaccaagt ggtgaattta gtagagaaga tgtagaaggc agaatggtag ttgtaccagg
    26281 gacttatcaa agtgtagaaa gcaatccaca aggatttgca gatgttttta aagcaccaat
    26341 agaaggattt atcgattcag ctgaagttgt aggttttgtt ttaatagttg gaggtgcttt
    26401 tggtattgta aataggactg gagctataga agcaggaata gcttcggtta tctctaagtt
    26461 taagggaaaa gaacttctta taattccaat atcaatgatt ttatttggac ttggaggtac
    26521 aacatttggg atggcagaag agacattacc attttatatg atatttgttc cacttatgac
    26581 atccttggga tatgattctc taacagcgat agcaattgta tttataggag cagcagcagg
    26641 agccgcagct tcaacaataa atccattttc agttggtatt gcacaggcac tagctcaact
    26701 tgctcctggt tcaggagtaa cttatagagt agttattttt atagcatata tactaataag
    26761 tatagcattt gtcatgtact atgctaagaa ggtaaaggaa aatcctgaaa gttcaatagt
    26821 atatgaaata gataaaaata ataaatcaat acttaatcaa acttcaacag aaataaaaga
    26881 atttactttt aaagaagtat ctgttcttgc tatatttgga atagggatgg caataatgat
    26941 ttggggtgtt ttaagtcaag ggtggtacat tccagaaata tcaatgtgtt ttgctgcgat
    27001 aggtgtgctt tctgggctgg ctggtagatt atctcaaatt gaaatttcag aaagttttat
    27061 agatggagca aaagatttag catcagcagc tcttgccata gctttagctc gtggaatcgt
    27121 aataattgct caaaatggat ttataataga tactatatta aattccgcag cagctttttt
    27181 aggtgggctt ccaaaggtta tatttgtata tttatcattt ttcttggaag ctgcattggc
    27241 atttttaatt ccatcatctt caggacttgc ttcacttaca gtacccgtac ttgctcctct
    27301 tggtgatttg gttaatatat cagcacaagt gatagtaact gcttatcaat ttggtgtagg
    27361 tcttacaaac tttataactc caacttcagg agttttgatg ggagcacttg cagtagccca
    27421 tataccattt tcaaaatggg taagattcat aatgcctatt ctgttgattt taacagctgt
    27481 atctctagtc tttttaacaa taggcattta tatagggttt taattaagta tatttttatt
    27541 taagatattt agtaatgata taaaatgata atatgttttc aataaattac cactaattta
    27601 attagtggta atttgttttt tgtatttaga aataaatgta tttacttgtg ttttgaatta
    27661 ttatctactt agacatagtt ttaattgtta tatttttatt tgattaagca ttgatttgtt
    27721 attttttata tttcatataa tgacatgaaa tataattttt atacaataaa tgataaaaat
    27781 ttataataaa tgtatatttt cttactcatt tcttaaaatt actcatttaa tttaataact
    27841 ctcatttcat atgtaaaatt tggaaaaaat taaaattaaa agtaaaaaac taaaaaaatt
    27901 aatattaatt tgaaatatat atgaaggttt ttggagaata cttacttatg ataggaaaaa
    27961 atgttaaaat aatagtgtaa tcaaatataa aggactgaaa taattaacag ttattaaata
    28021 ttaggagtgt aaaaatttat gggattaaaa gaatttgatt ttattgaaga gtctatcgat
    28081 atgttgagga caatgtcacc aacattagaa actatatcag atgaaataga agagtatttt
    28141 gaaaatatct tggatgaaaa gaatcaagaa tatataaatg taacctctag aataaaatca
    28201 gaatcaagtt taagagaaaa gataattaga aatagatatt taaaaaaata tggagaagca
    28261 agtaatctta ttcataatgt atctgactta ataggtttaa gaatcgagtg cagatttatt
    28321 gaggatgaaa acaaaatata tagacttttg agaaggtatt ttaataaaac agatgacaaa
    28381 ataaactatt ataacaaaga gaataagaat attaaattaa aactatctga gaggcaaccc
    28441 aataagcaaa aaaatggatt tgaaatatat aaaatagatg gagttttcgc gtatttagat
    28501 agagaagtaa aatttgaact tcaaattaaa tctcttgtaa atgtgttttg gagtgaaata
    28561 gaacataaaa taatttataa aaacaataca tatttacttg ctgacaaatt tataaaggat
    28621 atgatggatt ctataaagaa taatcttact atgatagata atcagctttt aagtatttat
    28681 aaaaactttc attcagggaa gtcttttaat atgaaagtga gtaaaaaaga aattgaaaaa
    28741 ttatttgcga aactagtata tgacgctttt tctgaaaaga tgaataaaag tataggtttt
    28801 gttgtagatt ttaaaaaacc atgtgagact atattgagct attcttttaa taagcaagat
    28861 ataagtgatg aagttttagg taattttatg cttgatgagt ttgcaagatt aaatgaaatt
    28921 gtaaacaagg atatagattt taatgagcaa atagaatttg aaagagaacc gacatttgat
    28981 gataagtttt gtaaagacct aggaaatcat tttagaagta gattaaacac agaatttcca
    29041 tggaacctgt tttttagaat attatttgaa atagagccat ataacaatac caaagacttt
    29101 gaaaattttg tagagtttat aaaagaaaat gtgctactag aagaaaatag ggaacaatta
    29161 ttatgccaat ttgaagaaga tagcaaactt ataattgaag atatatatga ttgcatattt
    29221 aatagtataa gtgagattga tagtgttgaa attttatata attataatct tgaaaaaata
    29281 aactttacat caagtgaaat tataactttt atatgtagag aacatgagtg ttatggtgaa
    29341 tacttagaag aaaaagaaaa gcttatgaat acatttaaag aaaagattat tcaaatcttt
    29401 gaataataag tcaatgctga agtggcgcta atgcgccatt tttcaaatat atatgaatta
    29461 agtaaaatta ttttggagga ggcgatttgt atagagaaaa caggtgtaat tttggcaggg
    29521 ggaaaaaatt ctagaatggg tagagataaa gcctttctag agttacatga aaagcttttt
    29581 attgaaattg caatagaagc atttaaaaac tttgatgagt tgataataat atctaataat
    29641 gaagaattat attctaaata cgatattaga gtttataatg atatagtaaa agatgttggt
    29701 ccaattggag gaatatatac tgctcttgaa tatgcaaagt atgatatagt tacaattgca
    29761 tgtgatatgc catatctaaa tagtgaagta gtcgaaagaa tagctaataa aatgaaggat
    29821 aaaagtgtga tttcagtgac aaatggaaag ttacaaccat tgtgttctgg atataaaaag
    29881 agtataataa ataaagtatc tttatgtata agggaaaatg atttaaagct cagaagcttt
    29941 atagataaaa tagataaaag ctatatatac tttgatgaag aagatttatt tttaaatgta
    30001 aacactgttg atgagtacaa aaaattaact aaagtttaat tagctatggt tgtaaaatag
    30061 agtaggattt atatggagga gagtttatga atttacttaa atgcgattct tgggcagtaa
    30121 tattaaataa tagcaataaa gaaagtaaag catataaaat attagatgaa cttaaaagga
    30181 atatgtacaa agttgttgct atagatgaag agaagaaacc tattgaaggt atagatgtgt
    30241 atgaatgttt aaaagacgtt ccacacaata ttgatgttgt agctattatt gataaacaat
    30301 ctaagatgga tgtaatttta gaagaagtag agcttttgga tatacaaaat atgtggtttg
    30361 aaaaaggaag ctttagtgaa atgatgatta aaaagactaa agatttaaaa ttaaacatag
    30421 aatataattt aagtttatat gatgagttga ctagataaaa ttatgtactt taataataaa
    30481 aatataatta gttagcaaaa catattattt catagtatag attggttaat gaaacattaa
    30541 attacaatat ttgttaaaaa attatgagtt acatgatata atatattaaa taggatacta
    30601 aggagttggt atattatgtt aatagtaact acagaaaaag tagaaggcaa aaagatatca
    30661 aaagttttag gcttagtgag aggaagtaca ataagagcaa aacatgttgg aaaggatata
    30721 ggagcaagtt ttaaaaatct tgttggagga gaacttactg gatataatga aatgcttact
    30781 gaagcaagac aaattgccat aggtagaatg gttgaagatg cagaagctaa aggtgcaaac
    30841 gcagtaatag catttagatt gtcttcagca tcagttatgc aaggggcagc agaaatgctt
    30901 gcttatggaa cagcagttgt tttagaagat gataatagta ttcttgaaaa ataaaatata
    30961 aatagttaaa aagaggcatc ttttaaaaat tttatggatg ccttttttta tttgaaaaaa
    31021 ctaatttcag aagaaatttt aattattatg acaataaaat tagggtgata ttatataaat
    31081 aagtaaaatt atattatata atgtatggta tagactttaa aaattttatt ggtagagaaa
    31141 aatatggaca atgttataat aattatagaa attaaaagta cttacattca ttatatatgt
    31201 tacatgtata attagtttta tatttaatgc agttttgaag tactatcttc attttgagaa
    31261 cgttggaata ataaaaaatg tatgtattat aagtgatata aataaaaaat aaatataata
    31321 tgttgtattg ctgatagaaa agggaataaa gtaaagtagg ttttattgaa agagattttt
    31381 atttatagga cttaatcaat gtatagaggg gggagagcat atgtttaatg ttgcaattat
    31441 aacacttagt gataaaggat atgaaggaaa aagagaagat ataacaggaa aaaaattaac
    31501 tgaatttgtt gaaaatacag gagcttataa agttactgaa tatgtactta taaaagatga
    31561 taaggaaatg ttaaaggaaa atattataag actttgtaat agtaatagaa tagatttaat
    31621 tcttacaaat ggaggtactg gtttttcaaa aagagatata actccagaag caactaagga
    31681 agtattggaa aaagaaatac caggtctgag cgaatatatg agaatgaaat ctacagaaat
    31741 tactaaaaag gctatactaa gtaggggtgt gagtggaata agaaataatt ctataataat
    31801 aaatttacct ggaagtccta aaggtgcagt tgaaaattta agttttataa ttgatgtttt
    31861 agatcatggc atagaaattt taagaggaca agttacagaa tgtgccacta aaaaaagtaa
    31921 atagtatata atctagatag ataaaaaata gacaaagagg tagatagagt atgattgata
    31981 agtatggaag aaaaatagac taccttcgta tttcacttac agataagtgt aatttaaggt
    32041 gtgtctattg tatgccacca gatgtaaaat ttgataaaaa ttatataaat gaaaatctaa
    32101 gttttgaaga ttacaagttc attataaagg ctatggctga acaaggtata acaaaagtta
    32161 gatttactgg aggagaacct cttttatatc ctaaattaaa tgagcttata aaatttacaa
    32221 aagaagaatg tggaataaat aatataggca tgaccactaa tgctattggg ctttctgata
    32281 gaatacttga gcttgaaaaa tgtggcttaa ataaagttaa tataagttta gactctttga
    32341 aggaatataa gtataaatcc ataacaagag gaggaaactt aaaagatgtt ttaaaatcaa
    32401 ttgaatcttg tttaaattta ggtataaagg taaagttaaa ttgcgttgct ataagtgggt
    32461 ttaatgatga tgagcttaaa gattttatgt ttttaacagt taaatcacca attgatgtaa
    32521 gatttataga acttatgcca ttaggtgagg ctaatagagt ttataagaag gggtatttta
    32581 atgtaaaaga aatgattgaa aaaatatatg gtttatataa agtcaaaaat gatgaaaaga
    32641 gtacagcaga atattatatg tttaaaggag ctaaaggaag gataggaatt ataactccat
    32701 taagctgttc attttgtaac acttgtaatc gtattagact tacttctagt ggtgcaataa
    32761 aattatgtct acattcaaaa gaagaaatag atataaaacc atttttacat aaaccattgt
    32821 tatttagaga atctatgaaa gatataataa aacaaaaacc agaaaaacat catttaatag
    32881 aaaataaatg tagtgataca aataggcgta tgtatgaaat tggaggataa gtaatgttaa
    32941 cacatataaa tgaaaaaggg tatgccaaga tggtggacat aagtgaaaaa gatgatacta
    33001 aaagaacagc tgtggctaca gctacaatta ctcttagtaa ggaagcttta gaaaaagtaa
    33061 aaaatggtca gataaaaaaa ggagatgtat tgtctgtggc tcaagttgca ggtataatgg
    33121 gagctaaaaa tacatcttca aacataccaa tgtgccatca gattaaatta gttggatgtg
    33181 atttagaatt tgatatagat gattctatgt ctgctattaa gatatatgca acctgtaaat
    33241 ctcttgggaa aactggagta gaaatggaag ctttaaatgc atgttcttta gcagcactta
    33301 caatttatga tatgtgtaaa gcagttgata aaaaaatggt tataagtaat atccatcttg
    33361 tggagaaaac tggtggaaaa tcaggagatt ttaagttcga gtaaattaat aatatattga
    33421 aaatttggag gaaatatggc taaggtagtg tcaataaata taagtgagaa aaagggtgta
    33481 attaaagttc ctgtacaatg tgcagagcta aaaataaatc atgggatagt tggagatgca
    33541 catgcaggaa actggcatcg tcagataagc ttacttggaa aagaaagcat agataaaatg
    33601 aaaatgaaag gctttgacca attaaaatat ggagattttg ctgaaaatat aactacagaa
    33661 ggtatagaag ttttttccct gcctattggt acaaagctaa gaatagggca atgtgaagtt
    33721 gaagtaactc aaataggaaa aaaatgtcac aatggatgcg aaattaagaa attaactggg
    33781 gattgtgtaa tgccacgaga aggaattttt gtacaggttc tgaaagaagg aattataaat
    33841 gtgaatgatt caatagatgt aatttaatga agttagtatt aaaatataat tataagtaaa
    33901 tattattaag atttaaatgt atattttaag agagaattaa ttttaataaa atattttagt
    33961 tataaattga aatattggtt gtataaagct atgaatgtaa aatcatagct ttttgttttg
    34021 tgattttaaa ata
//
LOCUS       DBGJFK010000038        33154 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.038, whole genome shotgun sequence.
ACCESSION   DBGJFK010000038 DBGJFK010000000
VERSION     DBGJFK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33154
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.038"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            246..1409
                     /locus_tag="ACOIAP_002122"
     CDS             246..1409
                     /locus_tag="ACOIAP_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGZ2639005.1"
                     /translation="MFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEELRR
                     FIDKISNNHGQFRVIFTGAGTSAYVGNSILPYLKNNNDIRKYIFEAIPTTDIVSNPYD
                     YLKKDVPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPQGELAKMTKNDEN
                     NYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVIDRK
                     DEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKIATVYDSPMGFRHGPKSF
                     IDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFKEK
                     YNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            1458..2309
                     /gene="gatY"
                     /locus_tag="ACOIAP_002123"
     CDS             1458..2309
                     /gene="gatY"
                     /locus_tag="ACOIAP_002123"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HGZ2639006.1"
                     /translation="MALVTTTSMLKKAQDGGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLNEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNKV"
     gene            2638..4539
                     /locus_tag="ACOIAP_002124"
     CDS             2638..4539
                     /locus_tag="ACOIAP_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2639007.1"
                     /translation="MRERIILEALKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFKGNRNITKYRNKFIDNIKLDNIRSTIKNVLNEHYLEANLTELEEILAQIIILYIRV
                     STRVVRSPSDLELYTEDLIIDELLDKIFGDKKYSLTYDEKYYLKQLIKLRTKDKKATI
                     KNIDKNKLQDIMCEFFRDIDKKYNSNFLEDKEFLNLFYLHIACLIERIKKNHKITNPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIKNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESFRFVDHIGNVSSPKQYILGLFDKNHFRCVKEKTKYK
                     DILDSMSQCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDINYENRVPKIIFMISLIKGNLELHKQISKYLSKIMTDKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            4542..5585
                     /gene="ypdE"
                     /locus_tag="ACOIAP_002125"
     CDS             4542..5585
                     /gene="ypdE"
                     /locus_tag="ACOIAP_002125"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGZ2639008.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELRAYSDKVICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLMTIGGVKPLAQFVQKVRITT
                     KEGKKIHAIINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTNFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELKKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMKIASENNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEKYRHIRNFI"
     gene            5600..5905
                     /locus_tag="ACOIAP_002126"
     CDS             5600..5905
                     /locus_tag="ACOIAP_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGZ2639009.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            6002..6337
                     /locus_tag="ACOIAP_002127"
     CDS             6002..6337
                     /locus_tag="ACOIAP_002127"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639010.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            6369..7691
                     /locus_tag="ACOIAP_002128"
     CDS             6369..7691
                     /locus_tag="ACOIAP_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGZ2639011.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGEDNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKIFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPIFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLTVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            7701..8771
                     /locus_tag="ACOIAP_002129"
     CDS             7701..8771
                     /locus_tag="ACOIAP_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGZ2639012.1"
                     /translation="MNNTIERLVSLIDKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQVLDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAISI
                     QEYLSLKNAGFKINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVAREIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            8776..9963
                     /locus_tag="ACOIAP_002130"
     CDS             8776..9963
                     /locus_tag="ACOIAP_002130"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGZ2639013.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKEAILKRASIGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVLNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDLKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETHIPKANVMKSDSSFLAWIDVR
                     GVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(10160..11032)
                     /locus_tag="ACOIAP_002131"
     CDS             complement(10160..11032)
                     /locus_tag="ACOIAP_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HGZ2639014.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWNGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVSYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPSCEQNDFSKHYL
                     EFKSRNDVEKINLSGSFTDDIISIGKLKNLQLNPELFKNDALIYTNIDEVSICNNNGS
                     KYVTISMKDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADNINSNKIYKDKKFINKLS
                     KGKVFTASYSININ"
     gene            complement(11426..11617)
                     /locus_tag="ACOIAP_002132"
     CDS             complement(11426..11617)
                     /locus_tag="ACOIAP_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639015.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            11837..12883
                     /gene="cobT"
                     /locus_tag="ACOIAP_002133"
     CDS             11837..12883
                     /gene="cobT"
                     /locus_tag="ACOIAP_002133"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HGZ2639016.1"
                     /translation="MSLLESISKNIYSLDSSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFNIIEASNYT
                     YKNMATFDEIDMGR"
     gene            12915..13475
                     /gene="cobU"
                     /locus_tag="ACOIAP_002134"
     CDS             12915..13475
                     /gene="cobU"
                     /locus_tag="ACOIAP_002134"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HGZ2639017.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCLDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFKHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIAG
                     RINQYIASKSNEVYFVVSGIPMKIKE"
     gene            13485..14258
                     /gene="cobS"
                     /locus_tag="ACOIAP_002135"
     CDS             13485..14258
                     /gene="cobS"
                     /locus_tag="ACOIAP_002135"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HGZ2639018.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLVGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRNKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKIGFIYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSTIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSEVVYLIYIYLLNFMFF"
     gene            14278..14892
                     /locus_tag="ACOIAP_002136"
     CDS             14278..14892
                     /locus_tag="ACOIAP_002136"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGZ2639019.1"
                     /translation="MIRLILIRHALTNDNKKGKLSGHINSCISEEGKLQINKITRYLS
                     NENIDKIYTTPSTRTKDTIEKISKLKLLEIEEKETLREISFGDFEGITFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLGSKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLDVDSGFTVIDKMNFTDFI"
     regulatory      14959..15138
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            15253..16767
                     /locus_tag="ACOIAP_002137"
     CDS             15253..16767
                     /locus_tag="ACOIAP_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HGZ2639020.1"
                     /translation="MGKKIMLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMAL
                     NSFITKEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSS
                     KYHDYKLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPV
                     IIVGDIDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKV
                     PVIGVVPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVS
                     IRYVDYGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQ
                     MLGKKLKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGK
                     KIKGYEIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEIS
                     FTRAILNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            16806..18182
                     /locus_tag="ACOIAP_002138"
     CDS             16806..18182
                     /locus_tag="ACOIAP_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HGZ2639021.1"
                     /translation="MKKILIAGTSSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYRELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDESVPNADYIYIGGGFPEIFGKELEANESMRVSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLNKGNE"
     gene            18183..19154
                     /gene="cbiB"
                     /locus_tag="ACOIAP_002139"
     CDS             18183..19154
                     /gene="cbiB"
                     /locus_tag="ACOIAP_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HGZ2639022.1"
                     /translation="MNILSIYIGYVTDLIIGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLSYDHRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            19186..20250
                     /locus_tag="ACOIAP_002140"
     CDS             19186..20250
                     /locus_tag="ACOIAP_002140"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HGZ2639023.1"
                     /translation="MKDLGHGANVDEMARLYGKDPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRKNISKYIDINPDFIIPGNGATEVIYLLMKSIKKRLAIINP
                     TFSEYRRSAKLNNLDIIDLELESNFKLNIDIIKENIERFDSLFICNPNNPSGNVQDLK
                     ELVNLLGKHNKVLIIDETFMEFVEDESKHSLVKYIESNKNIFIIKAVTKFFGMPGLRL
                     GYGLTSNAEIMNKIYEYKEPWTINSFADILSNFIFEDREYIKDSKEYYIKERSYMLQE
                     LRNIRNIKVYDTDANFILIRTYKKTAKELKKDLFKQGNILVRDASNFIGLDDSFIRVA
                     IKSHKDNKILIENMKNLLGD"
     gene            20252..21139
                     /locus_tag="ACOIAP_002141"
     CDS             20252..21139
                     /locus_tag="ACOIAP_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HGZ2639024.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKDTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVIILEPN
                     KVLDTMKIRLRQDYSRLKTENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     DKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKNMIDALCESNINSVYSK
                     IYTLNIINGGIKGEIEWNT"
     gene            21127..21759
                     /locus_tag="ACOIAP_002142"
     CDS             21127..21759
                     /locus_tag="ACOIAP_002142"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HGZ2639025.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVASIIDALRNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKERGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAEESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            21768..22994
                     /gene="cbiD"
                     /locus_tag="ACOIAP_002143"
     CDS             21768..22994
                     /gene="cbiD"
                     /locus_tag="ACOIAP_002143"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase
                     CbiD"
                     /protein_id="HGZ2639026.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLSLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVSKNDKNKEY
                     LTLKDIDGLSNNSESQSELYKFIRVYGGIGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRNLIGDNFESILGNNKVLKITIFAPQGEAVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRTSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKISAGIFNTHSKVADARSEILVANLALMGATYEFLN
                     KINQCLTTEEAVELINNSEYRQVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            22991..23599
                     /locus_tag="ACOIAP_002144"
     CDS             22991..23599
                     /locus_tag="ACOIAP_002144"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HGZ2639027.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYISKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREVIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            23589..24164
                     /locus_tag="ACOIAP_002145"
     CDS             23589..24164
                     /locus_tag="ACOIAP_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HGZ2639028.1"
                     /translation="MRNSEFVTGKVPITKEEVRAISISKLNLVNAKNFIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNIRKFNLKNIEVIKGYAPINLGLNTKVESI
                     FLGGTGNNLEEIIEWSKKNLVVGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            24157..24909
                     /locus_tag="ACOIAP_002146"
     CDS             24157..24909
                     /locus_tag="ACOIAP_002146"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HGZ2639029.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSDADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSRLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            24893..26014
                     /gene="cbiG"
                     /locus_tag="ACOIAP_002147"
     CDS             24893..26014
                     /gene="cbiG"
                     /locus_tag="ACOIAP_002147"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HGZ2639030.1"
                     /translation="MNIEGNIAIICITENGKKLAVKINSLVNNCVIYQIKNKKSNLNV
                     EETCVHTVQKKLSDFVGEIFNKFDYIVFIMATGIVVRSIAPYIISKFSDPAVLVMDEK
                     GENVISLLSGHIGGANSLTQYISSLIDANPVITTATDVNQKASLDMIAKKLNAYIDTF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLLESKDELRDSFSNIYIEKLVVVSN
                     KINCIEDIENLNLDNKFELYYSTEKIIKVIPKDIVIGIGCRRNTDSELMYNSLKEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKTLKVPFKTFSIDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            26011..26736
                     /gene="cobJ"
                     /locus_tag="ACOIAP_002148"
     CDS             26011..26736
                     /gene="cobJ"
                     /locus_tag="ACOIAP_002148"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HGZ2639031.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVAEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKDGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYIDGELMITPRGYTV"
     gene            26733..27485
                     /gene="cobK"
                     /locus_tag="ACOIAP_002149"
     CDS             26733..27485
                     /gene="cobK"
                     /locus_tag="ACOIAP_002149"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HGZ2639032.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAN
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKNAITCAKLSNIDYIRFERKSL
                     IDEIDYDNKFIVNTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIIAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            27504..28982
                     /locus_tag="ACOIAP_002150"
     CDS             27504..28982
                     /locus_tag="ACOIAP_002150"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HGZ2639033.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSYDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESDEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGVNAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEEDGFNVRVHLKGLGENSYIQDKFVRHALKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            29012..29917
                     /gene="hemC"
                     /locus_tag="ACOIAP_002151"
     CDS             29012..29917
                     /gene="hemC"
                     /locus_tag="ACOIAP_002151"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HGZ2639034.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLYGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPRGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSKIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            29907..31406
                     /gene="cobA"
                     /locus_tag="ACOIAP_002152"
     CDS             29907..31406
                     /gene="cobA"
                     /locus_tag="ACOIAP_002152"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HGZ2639035.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSNYLR
                     EAKPDCEFIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLNKISENLMKEGKDKNTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVELREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNIKLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELMPILNNSDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEDKKDEILDILNSNNIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTDTINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            31423..32394
                     /gene="hemB"
                     /locus_tag="ACOIAP_002153"
     CDS             31423..32394
                     /gene="hemB"
                     /locus_tag="ACOIAP_002153"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HGZ2639036.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEEEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINADMNVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGANMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKNKF"
     gene            32537..33115
                     /locus_tag="ACOIAP_002154"
     CDS             32537..33115
                     /locus_tag="ACOIAP_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HGZ2639037.1"
                     /translation="MLYPINLKLDDLDVVIIGGGEVAYRKCKNFLNFNKRVTIVSKQL
                     LNKFYDLKEYINIIEDDYKEVYIEKASIVIAATNNKVLNMEIGLYCRAEHKLVNVVDN
                     VEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEEIYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLITLDLEELKKFDI"
BASE COUNT        13417 a         3328 c         6107 g        10302 t
ORIGIN      
        1 tttggtctga acaagttttt atcgtaaaat aaaaatacta aagtatctag agtatgattt
       61 tattaaattt ttaaagacaa actataaaaa taatcaaaat atatagagta tattttatag
      121 tgagtttaag tagtaataaa aaatctaggc aagaaattaa aagaagggta tattttttta
      181 taccttaaag tggttataac ctcattacca aaaataaatg ttgtaagtat gaaaggagaa
      241 tgaaaatgtt taagttagaa gaacaaaaac taaaagattt aggagcaata ataacaacta
      301 atgaaataaa acaacaacct gaattatggt tagaaactta tgaaatctat aaatctaaca
      361 aagaagaact acgtagattt atagataaaa taagtaataa tcatggacag tttagagtta
      421 tatttacagg tgctggaact tcagcttatg taggaaactc aatactacct tatcttaaga
      481 ataacaatga cataagaaaa tacatatttg aagcaatacc tactacagat atagtttcaa
      541 acccatatga ttacttaaaa aaagatgtac caacgttatt aatttcattt gcgagaagtg
      601 gaaatagtcc tgaaagtttg gctgctttaa atttaggaaa taagattgta gataatttct
      661 accatttagc tataacttgt aatccacaag gagaactggc taagatgact aaaaacgacg
      721 aaaataatta cttgttatta atgccatcaa aatcaaatga tgaaggcttt gctatgacag
      781 gaagtttttc gtgtatgatg ttatctgcta tgttaatatt cgatagctta gaagatgatg
      841 tagaaaagtc atatataaat gcaataattg aaatgggaag aaatgttata gatagaaaag
      901 atgaaataca tgagttaata aataaagatt ttgatagagt tgtgtattta ggttcaggag
      961 gattaggtgg tttgacacaa gaagcacaac taaaactttt agaacttaca gcagggaaaa
     1021 tagctacggt gtatgattct cctatggggt ttagacatgg accaaaatca tttattgatg
     1081 aaaatacact tgtatttgaa tttgtatcta actgtttata tacaagaaaa tatgatttag
     1141 atgttttaga ggagataaaa agggataaaa ttgctaaatt cacttgtgca gtgtcagtag
     1201 aaaatgaaaa taacttctca ggaacaaagt ttgagtttaa agaaaagtat aataaattac
     1261 cagatgtgta tcttgcaatg ccatacatat tgtttgcaca aactatagca ttgtttgtat
     1321 cggtaaaggt tggaaataag ccagatacgc catcagctac aggaacggta aatcgagtag
     1381 taaaaggtgt aacaatatat gaatattaga agagaagatt aaaatattat aactaaataa
     1441 tttgggaggg tattaatgtg gcattagtaa caacaacatc aatgcttaaa aaggcacaag
     1501 atgggggata tgcagtagga gcatttaatg tagaaaatat ggaaatggta attgctgtta
     1561 tagaagctgc tgaggagtta aattctccag taatattaca aactactcca tctactgtaa
     1621 aatatgcagg tctcgattat tatctagcaa atgcaaaggt tgctgcggaa agagtaaaga
     1681 tacctgtagc aatgcatctg gaccatgggt caagttttga ccttgcaatg aaagctttaa
     1741 gaagtggata tacatcaata atgatagatg gttctcatga aagctttgaa aataatatat
     1801 ctatatctaa atcagtagta aaagcatgta gcccttctct tataccagtg gaagcagagc
     1861 ttggaaaagt tggaggaaaa gaagatgatt tagatggagg gaatagtaat gattatacaa
     1921 atccaaaaga ggcaaaagag tttgtcgata gaacaggaat atcttcattg gctattgcta
     1981 taggtactgc acatggattg tataagggag aacctaaaat agatttagat aggttatcag
     2041 aaattaaaaa tgtagtttca atacctttag tattgcatgg aggttcagga atacatgatg
     2101 atattataaa agaagctata aaaagaggta ttgcaaaagt taactatgca actgaattaa
     2161 gaattgcata tagtaaaggg gttaaaaaag ttttaaatga agattctgag gttatagacc
     2221 ctaaaaagta tggactagca gggcttcaat cagtaaagga ttttgtaaaa gaaaagatta
     2281 aagtatgtgg gtctgtaaat aaagtataaa aaataaaata tcctaaattt attttagata
     2341 agtttaggat atttgttata tgaaaatttt atattaatta tgggtaaatg gtgtattttt
     2401 ttcatttaat tgatgaaaaa tatcagcttt tattggtaaa gtattacata tataattaaa
     2461 atataataaa aattgaacta tatattttat tattatgaaa tatggatatt aaattttagt
     2521 gctaaaatgc acgaggatat aatattctat aaatgaaaac aaaaggttga ctttataaga
     2581 aaaaattttt tatgctactt tgaaaaatac aataataaca ctgagagagg tggggatatg
     2641 agagaacgca ttattcttga agcattaaaa aatagtagtg gttatctaaa catagattat
     2701 tttgcagata agttgggggt atctactcga actatcagaa atgaaataaa aaagatagaa
     2761 actataaaag aatgtaatgg tttcaaatta gaatataagt ctaaactagg atatattcta
     2821 aatattaaag accaagataa attcgagcat tacctaagaa acttaccctc agatttagtt
     2881 gaaaatccag aacaacggtt agaatctata atagtagaac ttttagtaaa tgaaggttat
     2941 aaaactatag aacagttaag taaaaaattt ttagtaagtt catctcaaat aaaaaatgat
     3001 ttaaaaaaga tagatgaaaa aataaaggat acagaattaa aattggagcg aaaggctcat
     3061 tatggaataa aaatagaagg gtctataaaa gaaattcaaa gtatactggt ggatagttac
     3121 tttaaaggga atagaaatat aacaaaatac agaaataaat ttatagataa tattaaacta
     3181 gataatatca gaagtacaat aaaaaatgta cttaatgaac attatttaga agcaaattta
     3241 accgaacttg aggaaatatt agcacaaatt attatattgt atataagagt tagcactaga
     3301 gtagtaagaa gtcctagtga tttagaatta tatacagaag atttaattat agacgaatta
     3361 ttagataaaa tttttggaga taagaagtat agccttactt atgatgaaaa gtattattta
     3421 aagcaactta taaaattaag gactaaggat aagaaagcca ccataaagaa cattgataag
     3481 aataaacttc aagatattat gtgcgaattt tttagagata tcgataaaaa gtataactct
     3541 aattttttag aagataaaga gttccttaac ttattttatt tacatattgc atgtttaata
     3601 gaacgtataa agaagaatca caagataaca aatccttttt cagttaaaat aagtcaacag
     3661 tatccaactg tttttaattt atctattcaa ttttcaaaaa tcatagaaaa tgagtatcac
     3721 ataaaaataa gtcaagatga aataggtttt atagctactc acattgctgt tccttttgaa
     3781 aagagagaag aggctaattt taataaaaaa tataaaatag caataatatg ctcttctggt
     3841 ggaggcagtg catttttgat aaatttgaga cttaaagaaa tctttccaaa tgctgaaata
     3901 aaaaactttt cattactaga agaaaaggct gtaatagaat ttgcgccaga tttgattttt
     3961 tcaataacaa atcttttatt tgaaataaat gctccagtta tacttataaa tgaaatttta
     4021 gacgaactgg attatttgga tattaaagaa agttttagat ttgtagacca tataggaaat
     4081 gtatcaagcc caaaacaata tatattaggt ctgtttgata agaatcactt taggtgtgta
     4141 aaagagaaaa ccaaatataa agatatcctt gatagtatgt cgcaatgtat agttgatgag
     4201 ggagcttgtt ctccgactta tcccaaagat gtgtgggaaa gagaaagcta tttgagcact
     4261 atttacacaa atggtgtagc gatacctcat ccaattgaaa tgacaggtaa taaaaatatt
     4321 atatcagtag ccttgataca aactgatatt aattatgaaa atagggtacc aaagattatt
     4381 ttcatgattt cattaataaa gggaaatcta gagcttcata agcaaatatc taaatattta
     4441 agtaagatta tgacagataa ggatatggta gatatgctaa ataagtcaca atcttatgag
     4501 gaatttatgt ataagctaaa aatctatctg ggaggttaga catgaatata gagtttttta
     4561 agaggttatc agaagcagat ggtatagcat ctaatgaaga agaggttaga catgttttat
     4621 tggaagaact aagagcttat agtgataaag ttatatgtga tggtctaggg agtataattt
     4681 tttctaagat aaaagatgaa agtgcaccaa acgtaatgat ttgtgctcat atggatgaag
     4741 ttggatttat ggtgagaagt atagacaaac ttggtatgat tcacctaatg acaataggag
     4801 gagtaaaacc tcttgcacag tttgtacaaa aagttagaat tacaacaaaa gaaggaaaga
     4861 aaatccacgc tatcataaat gctacatata ataatggtaa ggctgaaaat atatatgcag
     4921 atattggagc atatacagaa gaagatgtat acaacctagg gattaatgtt ggggatatgg
     4981 taacatatac aacaaacttt gaggaattta ctttgccaga ccgattagtg ggaaaagctt
     5041 ttgatgatag gataggatgt tttgtgatgg gagaagtttt aaaggaactt aagaaagaaa
     5101 atctaaattg taatattcat tttgcagcta caagcagtga agaagttgga ataagagggg
     5161 caaagacgtc aacgcagtta ataaatccag atatagtatt tgtaatagat gtagcatgtg
     5221 ctaagaatga gtttgtgagg gactatacaa atcagaaaca aattgataaa ggtgtaatgc
     5281 taatgcatag agataggact ttagtcccta gtagaaaaat gatagattat gtaatgaaaa
     5341 ttgctagtga aaataatata ccacttcaac atgatatgtt tgaatcaggt gggactgatg
     5401 gaggagaagc acatctcgta aatgaaggga aaccttgtgt agtaacttgt gtaccagtta
     5461 gatatggtca ttgtgcattt tcaatagtaa gtaataaaga tttggaaaac attataagat
     5521 tgtatacaca gttaatttta aattttgatg aagaaaaata tagacatata agaaatttta
     5581 tctaaaggag aataagaaaa tgtcaacaga agtacaaata atggaactta tatcaactgc
     5641 aggagagagt aaatcgaaag cttttgaggc tttaaaaaaa gttaagtcaa aagattttaa
     5701 aggagcaaaa ttgttaatag aggaggctcg taaaatagat attgaagctc acaggataca
     5761 aacagaatta ataactcaag atttaaatga agacgttgaa agcccagcaa tgagtctttt
     5821 aatggtacat gctcaagacc actatatgac ttctcagcta gcaaaagact tgatagaggc
     5881 tttgatatat tgtcttgata agtaattgta atgtagaaat agattattta tgtaaaaatt
     5941 cttttaaaag tttagatgct tttaagagat aataaaaata caaactttag gaggaattat
     6001 tatgaaaata ttattatgtt gtgcaggtgg attttctact aatatgttaa tgcaaaatat
     6061 gaaaaaggtg gtaaaagaga gtgctaaact caatgaaaaa gattttgagt ttacagctat
     6121 accagcagat tcaatagaaa gtgaagttga tgactgggat atagtactta tagggcctca
     6181 aatagctcac aaaatagatt tcttaaaagg aatattagag ccaaaaaata aaccttttgc
     6241 agtaatagat aaagatgtat atggaaaaat ggatggagct acagttatga agttggcatt
     6301 aataacttat aagaaacatc aattagctca aggataataa aaataatgag ggaaaaggga
     6361 gattagatat gttttcaaaa tttgaagcat ttatgaatag agtatttatg cctttagctc
     6421 ataaggttga caatcaacgt caccttggtt ctataaaggc tggtatggtt gctatgacac
     6481 cattcacaat attagggagt atatttgcaa tacttccagc acttccaaat atgcttggag
     6541 aagataatcc aataagcaaa ttcatactga acaattcagc aatattggac ttaccagtaa
     6601 gtctttccat aggcttaata ggattatatg cttgtatgtg tattgctttt aatctgggga
     6661 actactataa attatatata ccaggttgtg ttgcactatc aactttttct tttttattcc
     6721 tagtagcatc atttacacca gatggagctt tagaaatagg aaatttagga gctaaaggac
     6781 tatttacagg tatgatagca gggcttggtt ctgtggagtt atataatttt tgtaataaga
     6841 agaatatcac aataaaaatg ccagaaaatg tacctgattt tgtatctagg tcttttgaat
     6901 taatacctac tactataata gtttgtggaa cttttatagt tgctcgtttt atttcattaa
     6961 aaatatttgg agaattacct ccacagatac ttactcaatt tttatctcca ttagtaggaa
     7021 gtatggataa cccatggtca gttcttgcac ttaactttgc tatatgtact atattctttt
     7081 ttggaataca ttcatcagta tttagcccta taactagacc tataatgatt acatttatag
     7141 ctgaaaatat agcagctatg caagctggag aaacaatacc tcatttcttt acagcaggag
     7201 cttcaagtgc attctttgga tttacaggat gtggaattag tataggttgt gtaattgcat
     7261 gtatgttatc aaaaaatgct tcctataaga agattggacg tgtatcatta ttccctgcat
     7321 tatttgggat aaatgaacct atattatttg gagcaccaat aatattaaat ccaataatgt
     7381 ttataccaca tgtatttggt ggagctataa taggtacact accaatgttt tttatgcact
     7441 ggggatggtt agcaaagcca atatttgacc ctccatatgt aggagtattc ttagaaggat
     7501 ttttaactaa tggagattgg cattctatat tagcaaatgc attgcaatta gtattaacag
     7561 ttttattata ttggccattc tttaaaataa tggaacgtca acaaaataat aaaaaacaaa
     7621 aagaagaaac taagaatata ttctctaaag aagaagaaga cttattggat gatttaggat
     7681 tagatttcta atattttgtt atgaataata caatagagag actagtatcc ttaatcgata
     7741 aaagaggtgt tgacgctctt ttgattaaag caaaaaatac taaaagatat ataggggcat
     7801 tatcaggtag tggtgtatat gtgcttgtta ctaaagataa aaattatcaa gttctagatg
     7861 gcagatatat tgatgaagca gataaaaaaa cgactggttt tataaaaagg attgtatctc
     7921 aaggttctta tataccaact ataattgagt tattaaaaga attaaatata aaaaagttag
     7981 cgatagaaaa ccaagctata agtatacaag agtatctttc actaaaaaat gcaggtttta
     8041 aaatcaattt aataacaaat gaattatgga agctaagggc tataaaatct aaagaagaaa
     8101 ttgaacttat taaaaaggct tgtgagatta cagatgaagt atttgatgag gttatttctg
     8161 aaattaaaaa agatatgact gagctagaag tatcagctct aattcagtat catgcattga
     8221 aaaaaggtgc aagtggaatg tcttttgaga caatagtggt atcaggagaa agaggtgcaa
     8281 tgccacatgg aagacctaca aacaaaaagt tgaaagtgaa tgaagctata acaatagatt
     8341 ttggtgttgt ttatcaaggg tatcaatcag atatgactcg tacaatatct ataggtaaac
     8401 ctcctaaaat tattaaagag atatatgatg tagtattgga agcacaatta tctgcaatag
     8461 agtcaataaa ggaaggaact agggcaagtg atgttgacaa agtggctaga gaaattatag
     8521 ataaacatgg atttggcgaa tattttaatc atggactggg ccatggtata ggtcttggag
     8581 atggtgaagt tcccactcta aatccaaata gtgaagatat attagtggag ggaatggtaa
     8641 tgtcttgtga gccaggtatt tatattccaa atgtaggggg agttagaata gaagatgaca
     8701 ttgttataat agatggaaaa ggtgttccac tcaataagac atccaaagag tttataatat
     8761 taggagaata aaattatgaa atataatttt aataaagtat taaatcgtaa agaaggaaat
     8821 tgtaggaaat ggagcaacca cgtaattaaa gaaaaattcg gcttaaatga agatgcaatt
     8881 cctatggatt tagctgatat tgattttgag tgtgctcctg ctataaaaga agctatctta
     8941 aaaagagcat caataggaga ttatagttat acttttatag gagatgactt ttatgatgct
     9001 attataaatt ggaataaaag aagatttgat gtatatatag aaaaggattg gataaaatta
     9061 acttttggta ctgtttcaac ccttcattat atagtccaag catatactaa agaaggagaa
     9121 ggtgtattga taaatactcc tgcttatgac ccttttgcag aggctgtatt aaataataat
     9181 agaaagttgt gttgtagctc attaaaacta gataacaata gatattattt agatttagag
     9241 gatatggaaa atcaaatgaa atacgagaat ataagattgc ttatattctg tagtccacaa
     9301 aatccatcag gtcgtatatg gacaaaagaa gaactatatc aagtgtcaga gttatgttta
     9361 aagtataatg taattttggt aagtgatgaa attcatagag atataatatt taaagattat
     9421 agatttgtat ctttgtggaa tgctcatcca gaaatttata aaaatagtat aatctgtgta
     9481 tctcctaata aagggttcaa cttaggtgga ttaaaaacat catatgtatt aataagagat
     9541 ttaaaaatta gggagacttt attagaaagg ctaaaaagta attcaataac ttctccaaat
     9601 gtatttgcaa taccagcaat cgttgcagca tacaatgaaa gcgaagaatg gctagatgct
     9661 atgactagtt atgtagagga gaattttgaa atagtttatg atttctttga aactcatata
     9721 ccaaaagcca atgtgatgaa gtcagactct tcttttttag cctggataga tgtaagagga
     9781 gtgtttagaa atgaagaaga atctaaagaa ttttttagac atgcaaactt aactatggta
     9841 gttggaagtt attttgtgaa agatggagat ggatttattc gtattaatgt gggatgtcct
     9901 agagaaacat taaatgaggc tctaaataga atcaaaaaaa cgtatataag tatgtattgt
     9961 taaattataa aaaaggtata tatggtttat ataaaaacac attatttagt tatcaaatat
    10021 tactggaatt ttgcattcca gtaatatttt ttgattaagg aatattattg aagaatatta
    10081 aataatatta tttcatatcc ttatattaac ttatataaaa atattttatt attttgggaa
    10141 cgggttagct aacctttatc tagtttatat ttatactgta agaagcagta aaaacttttc
    10201 ctttactcag tttattaata aacttcttat ctttataaat tttattagaa tttatattat
    10261 cagcaagacc ataccaaggt tctatgcata aaaaaggagc agtagaattg gtttcactat
    10321 aataaggagt ccaaatacca actagaggga aatctttcat agatatagtt acatatttac
    10381 taccattatt attacatata gatacttcat ctatgttggt gtatatcaaa gcatcattct
    10441 tgaataattc tggatttaac tgtaagtttt ttaattttcc aatagatatt atatcatccg
    10501 taaaagaacc acttaaattg attttttcta catcatttct acttttaaat tcaaggtagt
    10561 gtttagaaaa atcattttgt tcgcaagaag gaaggttgaa tgcaggatgt ccacctatag
    10621 aaaagaatat atctttagag tcagtatttt tcacaatcca ttctacctca atgctgttat
    10681 catttaatgt atagtttatg attagctcaa aagaatatgg atatttcttt aaagtagatt
    10741 cattatctgt taatttataa gatacgaatg tatctccttt atctacaatc tcaaagtcca
    10801 tatctctagc aaatccatgc tgagtcatac tatataaatt ttcttctatt attgtttcat
    10861 tatcaaaaag tttacctact ataggaaaca gtataggtga ttgtctaccc caatattttt
    10921 tgttaccatt ccaaagaata tttttgtcgt attttttaga aaatatttta gttagttcag
    10981 caccaaaact gcttgattcg ataattaaat tttcattttg taatatattc atttaaaatc
    11041 tcctttatta tattttatga gtatattata ctataaagta taaagattat taaattttat
    11101 ttgatattat atttgaaagg tagattttag tatattttga aaattttgtt ttgaaaattt
    11161 gggattattt aagaaatttt gtattataaa tagaaggaaa tagataaatt gtatagaata
    11221 aaatatatta agataagtta ataatgttaa atgggaagtg agtttatgga aaaaccaaat
    11281 acaaaagttg ttaactttca agagtataaa gacagaaaaa acaaaagaga agtaaataga
    11341 gacgaacttt taaagcttat aaaaaaaatt gtaacttcaa aatagggagt tgttaaactc
    11401 cctattttaa tgggtttcat aataattaag acattctaag tccatctata taatctttga
    11461 attgtgagaa atctgattca ctacttaatt ctatagtttc tgaaccttcc gtataaaaat
    11521 tcttaagata gatagtataa ttattatcaa cacaatcatg ataaatacat ctatatccat
    11581 cttcatacaa gctttttaac ttagaaaaat catccacaat atcatctcct taaagttctt
    11641 ttaaatatat ttttacaaaa agcatctaat tgtatgcaaa ttgaaaatgt aaaataaagg
    11701 aaatgaatat aaaatgtaga ataattttta tatgtatgta aaaataaaaa gaaaaagtta
    11761 aaatttttag aaaataagag tgttttttat ctaaaaagag agtttaaaaa ataaaaaaat
    11821 gttgggagga taaaaaatga gtttattaga aagtatatca aaaaacatat attccctaga
    11881 tagttcttct attgaaaaaa caaagcagag attggatagg cttatacatc caactggaag
    11941 cttaggaaaa atagaagata tttgcatgca attagcagga atatttggta atgaaaattt
    12001 tgatacgagc aaaaaggtta taattgcttt tgctggagac catggtgtat atgaagaagg
    12061 agtagcacct gaccctcaaa atataacaaa actacaattt ccaaatttct ctaaaggcct
    12121 atgtggagtt ggagtaataa gtaaatttgt aggggcagat gttgtagctg tagatgtagg
    12181 aataaactgt gatgaaaaac tggatggagt attagattac aagataagaa aagggacatc
    12241 aaatatggca aaaggtccag ctatgagtaa acaagaagct attagatgtt tagagatagg
    12301 tattgaaata gcagaacagt gtatagaaaa agattataag gttattggta ttggggagat
    12361 gggtatagca aatactactc cgagcacagc aataatatct gtaatttcag gttgtgaccc
    12421 gttagaggtt actggtatag gtgcaggtct taagaaagaa agactaaagc ataaggctga
    12481 agtaattaga aaggctattg aaattaacaa tccaaatcca actgatggag tagatatttt
    12541 atctaaagta ggaggatttg aaataggctc aatggcaggt gttatactag gttgtagtgc
    12601 taataggatt ccagtagtaa ttgatgggtt tatttcttat gcagcagcat taattgcata
    12661 taagataaat ccaaaaacta gagaatatat gatagcatct catttatcag cagaatcagg
    12721 aactaaaaga gcattagaca tattaaaatt agaccctcta ttaaatatgg atatgagatt
    12781 aggtgaggga agtggagctg ctttagcatt taatataata gaagcttcaa attatactta
    12841 caaaaatatg gcaacttttg atgaaattga catgggaaga taaatataaa aatttaatat
    12901 gtaggagtgt tttgatgagt aaaattattc tagtaacagg aggcgctagg tcagggaaga
    12961 gtaactttgc agaaaaacta tgtttggaca gaaataataa tacagcttat atagcaacct
    13021 ctattccatt tgatgatgaa atgaaagata gagtaaaaaa acatcaagag aatagaccta
    13081 gaaactggaa tacctatgaa atatatgaag atatatattc cataattaaa gagatatata
    13141 aagaacatga aactgtcata ctggattgtg taacattatt agtaaataat ctaatgttta
    13201 aacacaattt aaatatagaa gagtctagtc aagaagaaat aaacaaatta gaacaataca
    13261 taaaagaaca agttgtcaaa cttattgaag aaatagaaaa aacaaattta tactttgtat
    13321 ttgtaacgaa tgaattaggt atgggaattg ttcctgggaa taaacttagt agaatttatg
    13381 ctgatattgc aggtcgcata aatcaatata tagcgtcaaa aagtaatgag gtttattttg
    13441 tagttagtgg catacctatg aagataaagg agtagtatgt gattatgaaa agatttattt
    13501 taatactaca gtttttgaca aggataccta taaaattaaa tgtaggattt gatgatgaat
    13561 tttataagtc aatagtatat tttccacttg taggttttgt cataggtata ttatcctatt
    13621 tagtaggatg gatttctatg cttttatttg aaccatttat agcttctata ataataactc
    13681 tagctggcgt cttaattact ggaggacttc atatagatgg attaggagat acatttgatg
    13741 caatatatag ttataggaat aaagaaaaaa tgcttgaaat aatgaaagat tcaagattag
    13801 gtacaaattc acttctagca attatgtttg tacttttatt aaagattgga ttcatctacg
    13861 atataataag taataattca ttgtgggtta taatttttat gccaatgatt gcaagattag
    13921 gagtaatgtt attgacatat aaaactgtga caccaaggga aaaaggaatg ggaaatttat
    13981 ttataggaaa attaactaca agtatgttaa taactgctat aatatacaca ttactgatag
    14041 ttgctcttat tactaaattt atatttttat tacctaatat agtgttgatt aaagtattag
    14101 gttcaactat agtagttttt gtatttataa tattattcaa aaaacatatt tataaaaaaa
    14161 ttgacggagt aacaggagat atattaggtt gtggaataga actttcagag gttgtatatt
    14221 taatttacat atatttgtta aattttatgt ttttttaaag taaaaagtgg tgataatatg
    14281 ataagattaa tattaataag acatgcacta acaaatgata ataaaaaagg aaaattatca
    14341 ggtcatataa atagttgtat tagtgaagaa ggtaaactac aaataaataa aattactaga
    14401 tatctgagta acgaaaacat agataagatt tatacaacac catctacacg tactaaagat
    14461 acaatagaaa aaatatcaaa attgaaatta ttagaaatag aagaaaaaga aactttaaga
    14521 gaaattagtt ttggagattt tgaaggaata acttttgaag aaattaaaat caaatatccc
    14581 aatgagtttg aaaaaatgat aaaagaaggt aacaactata ggtatccaaa tggagaaagt
    14641 ttgatagact cttataaaag agtggcaaaa gaaattgata atataatttt agaaaatgat
    14701 agtaatttag gttcaaagac aatacttata tgttctcatg caggaacaat aagaaatata
    14761 ataacacatt tgatttctgg tagctataag tatcattgga actttaaaat tgataatgcg
    14821 tctattacag ttttagatgt tgatagtgga tttactgtaa tagataaaat gaattttaca
    14881 gacttcatat aatttaatca aaatcaaata ttacaatctg tgtttgtaat atatctgtaa
    14941 aattagcaat gaaaatagaa tattagatta aaattaggtt cttaattaga tgttaaaagg
    15001 gaaaaaggtt agatgccttt gcagcccccg ctactgtgaa accaacgaaa ctataaatac
    15061 cactgtcagt ttgatgggaa ggttatagaa gtaggatgaa gttaagccag gatacctgcc
    15121 taatttaatt taaaacaaga ggtcttcggg gtgaaagatt tttaattaat atatataaaa
    15181 gtcctatctt tagaagcatt aggacttttt ttaatttggt ttttagtaaa ttttaacaag
    15241 gagggatgga aagtggggaa aaaaataatg ctacaaggaa cagcttcaaa tgtgggtaaa
    15301 agtgtcttag tagcaggttt gtgtagaata tttaaacaag atggttatac tgttgcgcct
    15361 tttaagtcac aaaatatggc tttaaattct tttataacta aagaaggatt agaaatggga
    15421 agagcgcaag tatttcaagc agaggctgcg aaaatagagc caatagctga tatgaatcca
    15481 gttttattaa aaccttctgg aaataataaa agtcaagtta ttgtaagagg taaagttgta
    15541 ggagaaatgc cttcttctaa gtatcatgat tataaactgg agttagtaga tgtattgaag
    15601 gaaaccttta atagcttaaa ttcaaggtat gatattgtgg ttatggaagg tgcaggaagt
    15661 aatgcagaga taaacctaaa agacagagat atctctaata tgggtatggc agaaatagct
    15721 gatgcacctg taataatagt cggagatatt gatagaggag gtgtgtttgc ctcattagca
    15781 ggaacaatgc ttttattaaa tgaagatgag aaaagaagag taaaaggtgt aataatcaat
    15841 aaattcagag gtaaaaaaga gcttttacaa gatggtgtaa agatgctaga agacatcata
    15901 aaagtacctg tcataggagt agtaccttat acagatataa aaatagaaga tgaagatagt
    15961 gtaactacta gatttaagaa aaaaatgaat aaaagcgata tacacataga aataattaga
    16021 actccacata tgtcaaattt tacagatttt aatatatttg agacacaaga agatgtaagt
    16081 attagatatg tagactatgg agaatcttta ggaaatccag atatattaat aatacctgga
    16141 actaaaagta ctatagacga tttaacatat ataagaaaaa gtggtcttga atcgcaaatc
    16201 aaaaatttac atagtcaagg taaattaata tttgggatat gtggtggata ccaaatgtta
    16261 ggtaaaaaat taaaagaccc ttatcatgtt gaaagtgaaa ttgaagaagt tgatggaata
    16321 ggtcttttag atacagaaac aacgtttgag aaagaaaaga ctacaacaca agtagaagcc
    16381 actattgttg aatgtatcag tgaatatatg aataacctta aaggaaagaa aataaaaggt
    16441 tatgaaattc atatgggcat tacaaagcga ggtaatgatg taaggagttt agatttaata
    16501 actaaaaaac ttgataaaga agtgaattat actgaaggaa gtgtaaataa agaggggaat
    16561 gtaattggga cttatcttca tggaatattt gatgaaataa gttttacaag agcaatttta
    16621 aacaatataa gaaagaaaaa aggtttagga gaattagaaa gcaaagtaaa ctcttttaat
    16681 gaatttaaag ataaagagta tgataagttg gctgattttt taagagaaca tttagatata
    16741 gagaaaatat atgaaattat gaaataatga taacctttat ttataattta ggtaggaggt
    16801 gtattatgaa aaaaatttta attgcgggta ctagtagtgg agtaggtaaa acaacaatat
    16861 cattaggaat aatgcaagct ttggttaaga gaaatatgaa agtacagcca tataaagtag
    16921 ggccagacta tatagaccct tcatatcaca cttttataac tggaagacat tccagaaatt
    16981 tagattctta tatgttagat gatgaaaaaa taaagtatat agtaaataag tcctcaaaag
    17041 atgcagatat ttcagtaata gaaggtgtta tgggcttata tgatggtttt ggaatagatt
    17101 tagataattg tacaagttca catacttcaa aggtattaaa gtcacctgtt atattagtta
    17161 taaatggtaa atctatggca gcatctagtg ctgctatggt acttgggtat agggaactag
    17221 ataaagatgt aaatataaaa ggtgttatag taaataatgt aaagactaat agccattatc
    17281 aaataattaa gagttctata gaaaaatatt gtaatgttga agtattgggg tattttcctc
    17341 caaataataa attctcttta gaatctcgac atctaggatt agttcctagt gtagaaatga
    17401 aatcactaag ggaaaaattt tatactttag cagatgaaat tgagcactat atagatattg
    17461 atagaataat tgaaatatca gaaagtgatg aatttgagag tgattttgat tttcaaactt
    17521 tgatagaaaa taataaaata aaagaacatg ttaataataa atcaatagct atagcatatg
    17581 ataaagcatt caacttttat tatagagaaa atatagagct tttagaagaa cttggtttag
    17641 aaataaacta ttttagccct cttgaagatg aatcagtgcc aaatgcagat tatatttata
    17701 ttggaggagg ttttccagaa atatttggaa aagaattaga agcaaacgag tcaatgagag
    17761 tttctatatt agaagcacat aacaataata tacctattta tgcagaatgt ggaggactga
    17821 tgtacctagg tgagaaacta ttgaatcaag aagaacaaga atttaatatg gttggtatat
    17881 tcagtggaat tagcaagatg acatcttctt taaagagatt tgggtattgc attggtgtag
    17941 ccaaggaaaa tactctttta tctaaaaaag gggaatctat taaaggtcat gagtttcatc
    18001 attcaatatt tgaaagtgat gaaaaatgtg tgtattcaat gagaaaagaa cgagatggaa
    18061 atatagtaga agagtgggat ggtggttata gtaaaggaaa cactttggct acatatcttc
    18121 atactcattt ttataataac ttaaattgta tagaaaattt tttgaacaaa ggaaatgagt
    18181 aaatgaatat tttatctatt tatatagggt atgtgacaga cttaattata ggagacccat
    18241 attcttttcc tcatccagtg agatttattg gtaaacttat aaattttact caaggtataa
    18301 taagaaaggt ctctaaaaat gataggcagt taaaattggg tggatttata ttatggttta
    18361 taactgttgg aataacatat ttaacaactt atgctatagt gaagctattt agttttaata
    18421 tattattgag tattgtagtg aatagtttta taatttatac aacactagcc acaaaatgtt
    18481 taaaagatga agcattaaaa atctataatg tattaaaaac tgaagatata gagaaatcta
    18541 ggattcagct atcttatata gtaggtaggg ataccactaa tttaagtgaa cctgagataa
    18601 taagagcaac tgtagaaact gttgcggaaa atactgtaga tggtataatt gcacctatgt
    18661 tttatgcgtt tattggagga gcaccacttg ctatggccta taaagctata aatacattgg
    18721 attcaacagt tggatataaa aataaaaagt ataaagatat tggttttgca tctgctaaga
    18781 ttgatgatat agccaattat ataccagcta gaatatctgt tattcttatg acaattggaa
    18841 gtttcttttt aagttatgat catagaaact gttttaaaat ttctattaga gatagaaaga
    18901 atcataaaag tccaaattgt gctttttcag agggtgcagt atctggtgct ctagggatac
    18961 aactgggagg taccaacgtt tattttgggg aaaaggtata taaaccaaca ataggggata
    19021 agcttaggga gatagataaa gaagatataa ttaaaactaa taaaattatg tatgcatctt
    19081 catttgtatc tatgttggta tttacactaa tatatgtgtt atgtaggatg attttaatca
    19141 acttaattat ataaattatt gtttgttaac ttaaggggga catagatgaa ggatttaggg
    19201 catggagcca atgtagatga aatggcaaga ttatatggga aagacccaaa agaaataatt
    19261 gattttagct caaatataaa tccaaatgta ttaccaaatt tagaaagata cattttaaaa
    19321 ggattagaag agtgtaggaa ttatccggat ataaattata caaacttgag aaaaaatata
    19381 tcaaaatata tagatataaa tccagacttt ataatacctg gaaatggtgc aacagaagtg
    19441 atttatttgc ttatgaagag tattaaaaaa agattggcta taataaatcc gactttttca
    19501 gagtatagaa gaagtgctaa gttaaataat ttagatatta tagatttaga gttagaaagt
    19561 aactttaaac ttaatataga tataataaaa gaaaatatag aaagatttga tagtttattt
    19621 atatgtaatc ctaataatcc tagtggtaat gtccaagatt taaaggaact tgttaacttg
    19681 ctaggtaaac ataataaggt actaataatt gatgaaactt tcatggaatt tgttgaagat
    19741 gaaagtaaac atagtttggt taaatatata gaatcaaata aaaatatatt cataattaaa
    19801 gctgtgacta aattttttgg tatgcctggt ttaagattag gatatggtct tacaagtaat
    19861 gctgaaatta tgaacaaaat ttatgaatac aaagagccat ggactattaa ttcttttgca
    19921 gatatactat ccaattttat ttttgaagat agagagtata ttaaagatag taaagaatat
    19981 tacataaaag aaagaagcta tatgttacaa gagttgagaa acataagaaa tataaaggtt
    20041 tatgatacag atgccaattt tattttgata agaacatata aaaaaacagc taaagaattg
    20101 aaaaaagatt tgttcaagca aggaaacata ttagttagag atgcgtctaa ttttatagga
    20161 ttagatgata gttttataag agtggctata aaatctcata aagataacaa aattcttata
    20221 gaaaatatga aaaatttatt gggtgattaa aatgaaatct tatggaatat gcccagcatc
    20281 ttgtggagaa tttgtacaag gtataattga tgatgaagaa tatttatgtt catatgcaat
    20341 agatatgtat tctaaagtgt atattgaaga aaaattagta gatataaatt tagggaggta
    20401 taagtcaagg ttagcaattg aaaaggtatt tgaaaaattt aatttaccta aaaaagatac
    20461 taaaaatatt tctttaaata taaatagtaa aatacctgtt ggaaaaggaa tggcaagttc
    20521 aactgctgat ataggagcta ccataaaggc aacattatca ttgatagata aagatttaag
    20581 tagtgaagag atttctaaat tggccgcaga aatagaacca acagattcta tatttataga
    20641 taaaaacagt atatttaatc ctctaaatgg gactgttata aaatacctag gaaatctgac
    20701 caatgctaaa gttataatac ttgaaccaaa caaagtacta gatactatga aaattaggtt
    20761 gaggcaagat tatagtagat taaaaacaga aaataaagaa gtcataaaaa aatcatttgc
    20821 tcttttagaa gaaggattga aaaaaaataa tttatctcta gttggagagg cttgtacttt
    20881 aagtagctta gcaaatgaga atatagacaa aaaagagtat ttaaatgaaa taataaaaat
    20941 atcaaaaaaa tatggagcat atggagtaaa tattgctcat agtggaactg tagtaggtat
    21001 tttaattgat aagttcatga atgataaaaa tatgatagat gccttgtgtg aatctaacat
    21061 aaattctgtc tatagtaaaa tttatacact aaacataatt aatggaggaa ttaaggggga
    21121 aatagaatgg aatacataaa gaatcctatg aaaatagaag aaaaaagttt tgaattgata
    21181 caagaaataa tagacgaaat tagaccagat tataaattta agaataatat cgaagaaaaa
    21241 ataataaaga gagctataca tactactgca gattttgatt acttagatat attaaaaata
    21301 tcagaagaag cagttgcgag tataatagat gcattaagaa ataatgcaag tatttatact
    21361 gatactaata tggctcttag tggtataaat aaaagaaagt tagaatcatt aggatgtaag
    21421 tataaatgtt tagtggcaga tgatgaaact gtaaaattag ctaaagaaag aggaattact
    21481 cgttctatgg cagcggtaga aattgcagct aaagaagaag gaagaaaaat attcgtttta
    21541 ggcaatgcac caacagcttt atataaagtt atggagatga aatcagaagg tagattagat
    21601 ttagatgcag ttataggagt tcctgtaggt tttgtaggag cagaagaatc aaaagatgaa
    21661 gttgaaaaaa cagatatacc atatataatt tctaaaggta gaaaaggtgg cagtaattta
    21721 gcagcagcaa tagtaaatgc tatattatat actatgtagg tacatatatg gaagaatatg
    21781 tatatataga tggtaaaaaa tatagaagag gatatactac aggttcatgt gcaacaggtg
    21841 catctaaggc tgctgtatat atgttgatta caaaaaatag aatcaatact ataaatatag
    21901 acactcctaa aggaatacca ttatcactaa aagttgataa tataaatatt tctgatacat
    21961 ttgtggaatg ttcaataaaa aaagatggtg gagatgatat agatgcaact cataccatgg
    22021 atatttatgc aagagctgaa attgtatcta aaaatgataa gaacaaagag tatcttactc
    22081 taaaggatat agatggttta agtaacaata gtgaatccca aagtgaactc tataagttta
    22141 ttcgggttta tggtggaatt ggtattggtg tggttacgaa aaaagggctt agtgtagatg
    22201 ttggtaagcc tgctataaat ccgactcctc ttaaaatgat aaatcatgaa ataagaaatc
    22261 ttataggaga taattttgaa tctatacttg gaaataataa agttttaaaa ataacaatct
    22321 ttgctccaca aggagaagct gtagcaaaaa aaacatttaa tccaagatta ggtatagttg
    22381 gagggatatc tataataggt acaactggga ttgttgaacc catgagtgat gagggctgga
    22441 agaagtctct atctatagaa cttcaaatga aaaaagaaca aggtttagat aaaataatat
    22501 tggttccagg aaatcatgga gaacagttta taagagaaaa attaaattta gatattaagt
    22561 atgtagttag gacaagtaat ttcataggtt atatgattaa agaagctcaa agaataggat
    22621 ataaaaaaat cttaatggca ggtcatatag gtaaatttat aaaaatatct gctggtattt
    22681 ttaatactca tagtaaggtg gcagatgcta gaagtgagat attagtggca aacttagctt
    22741 taatgggagc tacatacgaa tttttaaata aaataaatca atgcctaact actgaagaag
    22801 ctgtagaatt aataaataat agtgagtata gacaagtgta taatatattg agtaataaat
    22861 gcagggagag agtaaagcaa tacttgaatg aagattcaga tgatattgat gtagaagtaa
    22921 tcatattttc aatggataag tctttattag gtaaatcgga taatacagat gatttagtgg
    22981 aggtctttat atgataaaca taataggtct aggacctggt aacttagact atataacaaa
    23041 aaaaggtgaa aatttaattt ccacttctga tgtattaatt ggtggtaaga gaaatttaga
    23101 gtctataaaa aactttgaag gagaaaaaat agtcttagat tctaatttaa gagaaattat
    23161 agagtacata aataacaata aagaaaagca aatatcaata atagcatctg gtgacccatt
    23221 aatatatggg ataggtagat atatatctaa aaatattgat aataagatgc taaatatggt
    23281 ttctgggatt agttcattac agtacatatt ttcaaaaata tatgttgata tgaatgatgt
    23341 atatattaca agtagccatg gtaaagtacc agattttgat tacatattat cacataaaaa
    23401 agtatgtatg gttacagact ctaagatagg accaaaacaa ataagtagag aagtaataga
    23461 tagaaatcta aataaaatta ttgttgtagg agaaaatttg tcatatgaca atgaaaaaat
    23521 aacaatagca aaaccagaag agataataag aatggacaat tttgatatga atgttgtggt
    23581 gattttagat gaggaatagt gaatttgtaa caggtaaagt tccaattact aaggaagaag
    23641 ttagagcaat atcaataagc aagttaaact tagtaaatgc taaaaacttc atagacatag
    23701 gagctggaac aggaagtgta agtgttgaag ctgcatataa ttatcctaat ttaaaggtta
    23761 tatctataga gaaaaatgat gatgctatag agcttataga gaaaaatata aggaagttta
    23821 atttaaaaaa tatagaagtg ataaaaggat atgctccaat taacctagga ttaaatacta
    23881 aagttgagtc tatttttctt gggggaacag gaaataatct ggaagaaata atagaatggt
    23941 ctaaaaaaaa tttggttgta ggaggaagac ttgtagctaa ttttataata atagatacat
    24001 ttaatcaaac tttaaaactg cttaaaaagc atggatttaa agaaatagat gtatgtgttt
    24061 tgaatgtttc taaactagag aaactaggaa aaggtgaata ctttaaacca ctaaatccta
    24121 tatatataat atcttgtgaa aaaggggaaa atgatgatga ataaagtaca ttttgtagga
    24181 gcaggacctg gagataaaga gttgataaca ttaaaaggat ataaattatt aagtgatgca
    24241 gatgtagtga tatatgcagg ttcacttgtt aatcctgaac ttttggaata ctgtaaagaa
    24301 gattgccaaa tacataatag tgcacatatg gatttacaag agataataga tgttatgaga
    24361 gaaggtatag aaaataataa gtctgttgta agactgcaaa caggtgattt ttctatatat
    24421 ggttcaatta gagagcaagt ggaagatttg aataaattga atatagatta tgactgtact
    24481 ccaggagtaa gttctttttt aggtgcagca tcatctttag gagttgaata tacagttcca
    24541 gaaatttctc aaagtgtaat tataacaaga atggaaggta gaactccagt tccagaaaaa
    24601 gaatcaatac aatcatatgc taagcatcaa acatctatgg taatattttt atctgttcaa
    24661 gaaattgaga aagttgtgtc tagattgctg gaaggtggat atccaaaaga tactcctata
    24721 gcagttatat acaaagcaac ttgggcagat gaaaaaatag ttaaaggaac tttaagtgat
    24781 atagctgtaa aagttaaaga aaacaacata aataagaccg ctttaataat ggttggaaga
    24841 tttttaggag aagagtataa taattcaaag ttatatgata aggatttcaa acatgaatat
    24901 agagggtaat attgctataa tctgtatcac agaaaatggg aaaaaattag ctgtaaagat
    24961 aaattctcta gtaaataact gtgttatata tcaaataaaa aataaaaaaa gcaatttaaa
    25021 tgttgaagaa acgtgtgtac atacagttca aaagaaatta agtgattttg taggagaaat
    25081 atttaataaa tttgattaca tagtatttat aatggctaca ggtatagttg tacgaagtat
    25141 agcaccatac ataataagta agtttagcga ccctgcagtt ttggtaatgg atgaaaaagg
    25201 cgaaaacgta ataagtttat tgagtgggca tattggaggg gcaaacagtt tgacacagta
    25261 cataagtagt cttattgatg ctaatccagt aataacaaca gctactgatg taaatcaaaa
    25321 agcttcttta gatatgatag caaaaaaact aaatgcatat attgatactt ttagagaaag
    25381 tgtaaaagaa gtaaattcta tgctagtgaa caataaatgt gttggattat atattgatga
    25441 aggatatcaa gttgatacta gaggatttaa acttctagaa agtaaggatg agttaagaga
    25501 tagtttttca aatatatata tagaaaaatt agttgtagta agcaataaaa taaattgtat
    25561 tgaagatatt gagaatttaa acttagataa taaatttgaa ctttactata gtactgaaaa
    25621 aataataaaa gtaattccaa aagatatagt aataggaatt ggatgtagaa gaaacacaga
    25681 tagtgagttg atgtataatt cacttaaaga gtttcttaat aaacaaaata tagatattag
    25741 agcaataaat acagttggaa gtatagaact gaaaaaagac gaaaaagcaa taattgaatt
    25801 atcaaaaaca ctaaaagtgc catttaagac attttcaata gatgaaatat ctaaggttga
    25861 taatcttttt gataaatctg attttgttaa aaaaaatgtg ggcgtgtatt cagtagcaga
    25921 gcctgtagca tatcttttga gcaaaggtaa tttgttagtt gaaaaacata aatataaagg
    25981 aataactttt tcagtgggga gaataaaaat atgatatacg ttgtaggaat tggaccagga
    26041 agtaaagata caatgacttt agaagcaata aaagcaatag aagattctga ggctattgtt
    26101 ggatataaga cttatataaa attaatagaa gaatttatac aagataaaga aataatccaa
    26161 aatggtatga ggcaagaagt tgatagatgt aaacaagcag tagcggaagc aaaaaaagga
    26221 aaaaaagtag cagttgtaag cagtggtgat gctggaatat atgggatggc aggtcttatt
    26281 ttagaattaa tatctaaaga agatgaagat ataaaagtaa aggtaattcc aggtgttact
    26341 gcaagtattg gtgcagcagc tatactcgga gctcctatta tgcatgattt ttgtcacata
    26401 agcttgagtg atttaatgac tccgtgggaa gtaattgaaa aacgattgag attagctgct
    26461 gaagctgatt ttgtaatttg tttgtataat ccaagaagta agggaagaag tgaacatcta
    26521 agcaaagcat ttaaaataat gggtgagttt aaagatggag atacacctgt tggagtggta
    26581 aaagatgtag gtagagaaaa agaagaaaag tttgtatgta cttttgaaaa tatggacttt
    26641 gaaaaagtcg atatgactac aatggttata ataggaaata aatctactta tattgatggt
    26701 gaattgatga taactccaag aggttataca gtatgatttt aattttagga ggaacttcag
    26761 atagtttatc tatatgtgat aagataaatg aactgaaaaa ccaaccatat attctttcag
    26821 tgactacaga ttatggaagg gaacttgcac aacaacatgc aaataatgta attttaggta
    26881 agcttggaaa agaagatatg ttaaaattta taaaggataa taatatagta aaaataatag
    26941 atgccactca tccttatgca gttgaagtat ccaaaaatgc tattacttgt gcaaaattat
    27001 cgaatataga ttatataaga tttgagagaa aatctttaat tgatgaaata gattatgata
    27061 ataaatttat agtgaataca atcgaagaag cctgtgaaat agcaaataaa atagggacaa
    27121 atatattcat aggaacagga agtaaaaatt tgaacaggtt tatagaggaa ataagtgata
    27181 aaaatttagt tgtgagagtt cttccaacta gtgaagtcat attaagttgt gaaaaattag
    27241 gtttaagtgc agacaatata atagctatga aaggtccgtt tagccagtat ataaatgaag
    27301 aaacatataa acattacaat atagatttag ttataacaaa agaaagtgga atagctggtg
    27361 gattcttaga gaaggtaaat gcatgtaaaa ctttcaatat accagtaata attataaaaa
    27421 gagaatcaat taactacgaa aatgtattta atgacataaa taaaattaaa gacatacttg
    27481 tgtaattttt aggaggagaa tatatgaaga aagccttatt agtagtgagt tttggtacaa
    27541 gctatcatga aacgagagaa aagacaatag atatatgtga agataaaata aaaaattcat
    27601 taaaaagtta tgattttttt agagcatata catcaaatat gataataaat aaaataaaaa
    27661 aaagagatgg aatagaaata gataatccaa tacaagcttt agataaaata tatgagcaag
    27721 gatatgatga agtaataatc caaacacttc atattatatg tggcgaagaa tttaacaaat
    27781 taaaagagca agtagatggc tattcttcca aattcaaaaa gattgtatta ggaagacctt
    27841 tacttacaca tattgaagat tatcaggaag ctgtagaggc aattaagcat caaattcctc
    27901 atatggaaag tgatgaagca gtagtattta tgggacacgg aacacttcat gaatcacatt
    27961 cagcgtatcc tgcattagaa tacatgctta gagacaatgg agtaaatgct tatgttggta
    28021 cagttgaagg gtatccagaa atagaacatg taataagaag actgaaagaa ggaaatataa
    28081 aaactgtaaa tttgatgcca tttatgttag ttgcaggaga ccatgctata aatgatatgg
    28141 caggagatga agaagattct tggaaaacaa tattagaaga agatggattt aatgtaagag
    28201 ttcatttaaa agggctagga gaaaattcct atatacaaga taaatttgtt cgtcatgctt
    28261 taaaatgtgc agagaatgct aagttttatg gtataggagc gggtccggga gatggttctt
    28321 tacttacaat aaaagcagtt aatactttaa agaaattgga tattctatac actccagaat
    28381 caaaaaaggg tggagatagt ctagctttat caatagttag tgaatactta cctgaatcag
    28441 tggaaataaa atctaggcat tttccaatga gttttgatgg gaatgaaaaa agtttagctt
    28501 gggataatgt ggcacaagaa attatatcag atgttaatga tggtaaaaat gtaggatttg
    28561 ttacattagg agaccctatg atttatagca cgtatgtata tataatgaaa agaatattag
    28621 gagaggtaga agtcgaaact ataccaggaa tttcatcatt ttcgaatata gcatctaatc
    28681 aaaattttcc attagttatg gacaaagaag cattagtggt aattccttgt actatggaag
    28741 atgataaaat agagtatgct ttgcaaaatt ataactcaat agtattgatg aaggtatata
    28801 aaaatttcaa agaaataata aaaaaattag aaaagtatga tttaatagaa catgctattt
    28861 tagtaagtaa ttcttcccaa gaaagcgaaa atgtatttac agatttaaaa gaagcgcacc
    28921 ttgaagataa gatatcttat ttttctacta tactagtaaa taaagataat aaaataaaat
    28981 aggtgaaagc aatatttaaa ggagatttaa tatgaatata gtggttggaa ctaggggtag
    29041 taatctagca cttatacaaa cagaatgggt aataaatgaa ttgaaaaaga agtatccaga
    29101 aattagtttt gagattaaaa tcataaagac aaaaggagat ttaattcaaa atgtatcact
    29161 tgataaaata ggtgataaag gattgtttgt taaagaaata gagcaacaat tattgtatgg
    29221 aaaaatagac atagcagtac atagtatgaa agatatgcct tcttatttag cagatggatt
    29281 aaaatttgct catacgccta agagagaaga cccaagagat gttctaatac ttagggaagg
    29341 atataaaaat ttagatgatt tgcctcgtgg agcagtaata ggaacaggaa gcaaaagaag
    29401 aaagtttcaa ttattgaaac aaagacctga tttaaatata gtacaagtta gaggtaatgt
    29461 ggaaactagg ataagaaaaa taaaagatga aaatatgcat ggtattgtgt tggcagcatc
    29521 aggaataatt agagctaatt tacaagataa aataagttct tatttacctg ttgatgttgt
    29581 tattccagca cctgcccaag gagccttagc tatagaaatt agaagtaacg atagtaagat
    29641 agagggaata gtaaattcac tgaaagatga gaatacagaa attcaaatat tggctgaaag
    29701 aggtttttta gatggtgtaa atggaagttg tcatattcca atggcagctt attgtgaaat
    29761 aatccaagat aaaatacatc ttactggatt atatggagat tcagaaggaa aaaaagtagt
    29821 aatcaagtct atagatggag atatttcttc tcctagagag ttaggtttaa agttagctaa
    29881 acttgtgttg aaggagtatg agaattatga agggtaaggt ttacttagta ggggcaggac
    29941 caggtgatta taaactcatg actttaaagg gtttagagtg tataagaaaa tcggatgtaa
    30001 tagtatatga tagattagca aatagtaatt atttaagaga agctaagcct gattgtgaat
    30061 ttatatatgt aggaaaggca tcgagtaatc atattttgcc acaagaagat ataaatagaa
    30121 ttatagcaga aaaagctaaa gaaggaaaaa ttgtaactcg tcttaaaggg ggagaccctt
    30181 atgtatttgg tagaggggga gaagaagcag agactttagt agatgaaggt atagaatttg
    30241 aagtagttcc tggtataact tctgcaatag gaggtttatg ttatgcgggt attcctataa
    30301 cacatagaga ccatgcttcg tcatttcatg taataacagg tcatctgaag ggtgatgata
    30361 gtggagaatt aaactggaat gctcttgcaa ataataaagg tactcttgtg tttttgatgg
    30421 gaatctcaaa cctaaataaa ataagtgaaa acttaatgaa agaaggtaaa gataagaata
    30481 cacctgttgc tcttataagt tgggcaacta gatataatca aagagttgtt acatctacac
    30541 ttgaaaatgt ttatgaaact gctattaaag aagaggtaaa accgccaact cttatagtag
    30601 ttggaagtgt tgtagaactt agagaaaagt tgaatttctt tgaaagtaaa cctttatttg
    30661 gaaaaagtat tgctgtaact aggtctagaa atcagaatag tgtattagta gaaaaaataa
    30721 tggatttagg tggaaatcca atagaaatac ctactattaa ggtagaaaaa atacaaaaca
    30781 atattaaatt agaaaatgaa ataaaaaata taaataagta taattatcta atactaacta
    30841 gtaaaaatgc cgtagaaatt ttctttgaaa agatatatga aatgaatttt gatttaagaa
    30901 tactatctaa tttaaaggta tgtgctatag gttctgctac atcaaacgag ttgaaaaaga
    30961 gaggaattat agcagatata gtacctaaaa aatttgtggc agaatcactg tatgaagagt
    31021 taatgcctat tttaaataat agtgataata tacttatacc tagagcagaa aatgctagag
    31081 attatctggt tgacaaactt aaggccattt gtgaagtaac agaagtacat atatatagaa
    31141 cagtaataga tgaggataaa aaagatgaga tattagatat tttaaattct aataatatag
    31201 attatataac atttactagt tcctcaacag taaataatct cgttgaaatt ataggaaaag
    31261 aaaatattaa aatattagaa aaaataaaaa cattatctat agggcctata actacagata
    31321 caataaatag tttgggaata aaattgtaca aagaatctgc tacatctact atagattcgt
    31381 tagtagattt aattataaaa aattaatttt ggaggcttga atatgttaag aagaccaaga
    31441 agactaagag caagtaaagc aatcagaaat ttggtaagag aaactaaagt gaatgtagaa
    31501 gatttaatat atccactgtt tgtagtagag ggggaaaata taaaagaaga aattaaatct
    31561 ttaccagatg tctatcattt atcaatagac atgttagaag aagaaataaa agaaataagt
    31621 gagttgggaa ttgaacatat aatgttattt ggtgttccag atgaaaaaga tgagtgtgct
    31681 tcacaagctt ttaatgataa tggaatagtt caaaaggcaa ttagaaaggt aaaagaaata
    31741 aatgcagata tgaatgtaat aacagatgtc tgtatgtgcc aatatacaag tcatggacat
    31801 tgtgggattt taactgatac tggttatgtt gataatgata aatcattaga gtatctagct
    31861 aaaatatctg taagccatgc taaagcagga gccaatatgg ttgctccatc tgatatgatg
    31921 gatggaagaa tacaagcaat aagagaagct ttagatgaaa atggattaga aaatgttgga
    31981 attatggctt atagtgttaa gtatgcttca aattattatg gaccttttag agaagcagct
    32041 cactcagcac catcttttgg agatagaaaa acatatcaaa tggatccagc aaatagtaat
    32101 gaagctataa tagagactga acttgatata ttagaaggtg cagatatact tatggttaaa
    32161 cctgcattat catatttaga tattataaga agggttaaag ataattttga tttacctcta
    32221 gcagcttata atgtaagtgg agaatactct atgcttaagt ttgctgtgaa ggaaggttta
    32281 ttaaatgaag atgtaattct tgaatcaatt acatctataa aaagagcagg agcagatata
    32341 ataataactt attttgctaa ggatattgcc aagttattaa aaaataaatt ttagctagaa
    32401 aaagaatttt aaaaagtata ggaattgtaa ttagatatta tataatattt ttatttaatt
    32461 tgttgaataa gaatagatac taatttataa tttctatgct ttatttgtat aatcaaataa
    32521 agtttggagg tataaaatgc tatatcctat taatttaaaa ttagatgact tagatgtagt
    32581 tataattggt ggaggagaag ttgcatatag aaaatgtaaa aactttttaa atttcaataa
    32641 aagagttact atagtttcta aacaactgtt aaataagttt tatgatttga aagaatacat
    32701 aaatataata gaagatgatt ataaagaagt gtatatagaa aaagcctcta tagtaattgc
    32761 tgcaacaaac aataaagtat tgaatatgga aataggatta tattgtagag cggaacataa
    32821 attagtaaat gttgttgata atgtagaaat atcaaatttt actgttccat catatataaa
    32881 aagaggcgat ttacttataa gtgtatctac tggaggcaag agtccttcac tgtcgtcaaa
    32941 gataaaaaaa gagattgaag agatatatac tgaagattat gaggagtatt taaatgtatt
    33001 aggagatata agaaaaaagg ttataaaaaa atacgaagat aaaagtaaaa gaaaagatgt
    33061 gcttaacatg ttgataacac ttgacttaga agaacttaag aagtttgata tataaaaaat
    33121 aaaataaaaa atgttaaaaa agtgttgacg gatt
//
LOCUS       DBGJFK010000039        32143 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.039, whole genome shotgun sequence.
ACCESSION   DBGJFK010000039 DBGJFK010000000
VERSION     DBGJFK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32143
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.039"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..280
                     /locus_tag="ACOIAP_002155"
     CDS             <1..280
                     /locus_tag="ACOIAP_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGZ2639038.1"
                     /translation="KLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNK
                     CGYKNEEVKDLNIRDWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            410..1144
                     /locus_tag="ACOIAP_002156"
     CDS             410..1144
                     /locus_tag="ACOIAP_002156"
                     /inference="COORDINATES: protein motif:HMM:NF012472.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGZ2639039.1"
                     /translation="MEEKKKEGKIKNIGFSFHDSAELLDKVLSEHPEVDFVQLQINYL
                     DWDNESIQSRKCYEVAQKHNKPVIVMEPVKGGTLAKIPEKAEKLLNDYNSDMSIPSWA
                     IRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFIQEEYNIIDEAVGIINESILVP
                     CTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNYTKTYGKASDCIEC
                     KQCEESCPQHIKIIDALKNVAEIFEK"
     gene            1180..1593
                     /locus_tag="ACOIAP_002157"
     CDS             1180..1593
                     /locus_tag="ACOIAP_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2639040.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIQARKELLIEQRNQLAKRMEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEEVSYE"
     gene            1586..2125
                     /locus_tag="ACOIAP_002158"
     CDS             1586..2125
                     /locus_tag="ACOIAP_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2639041.1"
                     /translation="MSKHVLIVSASPRKGGNSDLLCDQFTQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYKKEASCPQKDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVSAADENIADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNI
                     GDIKGSEAMKQAYEMGKMA"
     gene            complement(2315..2800)
                     /locus_tag="ACOIAP_002159"
     CDS             complement(2315..2800)
                     /locus_tag="ACOIAP_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639042.1"
                     /translation="MNKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEKCSKTIKNSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEIDWKNLEKLITKENNIMQES
                     V"
     gene            3652..4029
                     /locus_tag="ACOIAP_002160"
     CDS             3652..4029
                     /locus_tag="ACOIAP_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGZ2639043.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            4429..6237
                     /locus_tag="ACOIAP_002161"
     CDS             4429..6237
                     /locus_tag="ACOIAP_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2639044.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEVSKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHVKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNICKNKDINIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQS"
     gene            6720..7934
                     /gene="dpaL"
                     /locus_tag="ACOIAP_002162"
     CDS             6720..7934
                     /gene="dpaL"
                     /locus_tag="ACOIAP_002162"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HGZ2639045.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLRDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSDEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGAEASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            8179..9366
                     /locus_tag="ACOIAP_002163"
     CDS             8179..9366
                     /locus_tag="ACOIAP_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HGZ2639046.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            9382..10965
                     /locus_tag="ACOIAP_002164"
     CDS             9382..10965
                     /locus_tag="ACOIAP_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2639047.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDDNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDVIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIRDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            10993..12321
                     /gene="ssnA"
                     /locus_tag="ACOIAP_002165"
     CDS             10993..12321
                     /gene="ssnA"
                     /locus_tag="ACOIAP_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HGZ2639048.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTNEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISSEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            12466..13818
                     /locus_tag="ACOIAP_002166"
     CDS             12466..13818
                     /locus_tag="ACOIAP_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGZ2639049.1"
                     /translation="MSQDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLRFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVILNIFFNELGSKKEKNNKVEEAK
                     "
     gene            14008..15117
                     /locus_tag="ACOIAP_002167"
     CDS             14008..15117
                     /locus_tag="ACOIAP_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2639050.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKKTGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMTARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            15396..16787
                     /gene="hydA"
                     /locus_tag="ACOIAP_002168"
     CDS             15396..16787
                     /gene="hydA"
                     /locus_tag="ACOIAP_002168"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HGZ2639051.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGATKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     EGLEEWHEKAKDKCYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKAENNLSPKYHQLTRPAILEAE
                     ATSRLMKIAEVANSKVYVVHLSCRESLEEVLKAKQRGVDVIVETCPQYLLLNDGLYDL
                     DGFESAKYVMSPPLRDKENNEILWNAISDNQIDTIGTDHCSFNYRGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGAIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            16781..19342
                     /gene="xdh"
                     /locus_tag="ACOIAP_002169"
     CDS             16781..19342
                     /gene="xdh"
                     /locus_tag="ACOIAP_002169"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004854 - xanthine dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0046415 - urate metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HGZ2639052.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVREHLVRGNAEEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAIAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     VTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASSKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVMLDENGRLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVKSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            19494..20840
                     /gene="rpoN"
                     /locus_tag="ACOIAP_002170"
     CDS             19494..20840
                     /gene="rpoN"
                     /locus_tag="ACOIAP_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HGZ2639053.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            21586..22608
                     /locus_tag="ACOIAP_002171"
     CDS             21586..22608
                     /locus_tag="ACOIAP_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGZ2639054.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSSL"
     gene            22668..23675
                     /gene="gap"
                     /locus_tag="ACOIAP_002172"
     CDS             22668..23675
                     /gene="gap"
                     /locus_tag="ACOIAP_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGZ2639055.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            23897..25099
                     /gene="pgk"
                     /locus_tag="ACOIAP_002173"
     CDS             23897..25099
                     /gene="pgk"
                     /locus_tag="ACOIAP_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGZ2639056.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEEMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEGYMGLDMGPKTIANFVKTIKESKTIVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            25125..25868
                     /gene="tpiA"
                     /locus_tag="ACOIAP_002174"
     CDS             25125..25868
                     /gene="tpiA"
                     /locus_tag="ACOIAP_002174"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGZ2639057.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCRVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            25880..27409
                     /gene="gpmI"
                     /locus_tag="ACOIAP_002175"
     CDS             25880..27409
                     /gene="gpmI"
                     /locus_tag="ACOIAP_002175"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046537 -
                     2,3-bisphosphoglycerate-independent phosphoglycerate
                     mutase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HGZ2639058.1"
                     /translation="MKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTLI
                     NASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMDN
                     AKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALEY
                     AKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKATSIEEAIQ
                     NSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDGF
                     KREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAHV
                     TFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVLN
                     FANPDMVGHTGSIEAAVKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPET
                     GKTVTAHSINPVPFIVVGQEYENAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLIS
                     K"
     gene            27997..29289
                     /gene="eno"
                     /locus_tag="ACOIAP_002176"
     CDS             27997..29289
                     /gene="eno"
                     /locus_tag="ACOIAP_002176"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HGZ2639059.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            complement(29578..29814)
                     /locus_tag="ACOIAP_002177"
     CDS             complement(29578..29814)
                     /locus_tag="ACOIAP_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGZ2639060.1"
                     /translation="MNAIKELSNLWHNVGIQMKTEMCSGKYPTISGISLVELSILEIV
                     EQHPNSMIKEISSTLEFPKSTLTSDVKRLELKNL"
     gene            29886..30107
                     /locus_tag="ACOIAP_002178"
     CDS             29886..30107
                     /locus_tag="ACOIAP_002178"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639061.1"
                     /translation="MVFYEFRYFRPAFWGTPVAKKGLQFCIDGLRNLGYPYITIWVLK
                     DNIRVIKFYKKMVLLVMILRKIYVLEKNY"
     gene            30250..30474
                     /gene="secG"
                     /locus_tag="ACOIAP_002179"
     CDS             30250..30474
                     /gene="secG"
                     /locus_tag="ACOIAP_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGZ2639062.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(30834..31772)
                     /locus_tag="ACOIAP_002180"
     CDS             complement(30834..31772)
                     /locus_tag="ACOIAP_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HGZ2639063.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDVHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKNNKTRGALIQ
                     GIFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVIILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIIFGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMSQQ
                     MDSDSELAGQIVVFTSAFSIITVFLIIFILKQNNLI"
     gene            complement(31760..>32143)
                     /locus_tag="ACOIAP_002181"
     CDS             complement(31760..>32143)
                     /locus_tag="ACOIAP_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGZ2639064.1"
                     /translation="KHVLITTNNIENYINFYKKFGFSFKETSEKYKFNAGNVKINLNI
                     KGHEFLPQGENVQTISTNLCFKIDTNIDEPKKYLEQNEIQIKRVIVECTEVFSNMKSI
                     CFKKTDVNLIELSNHRILESKPWKI"
BASE COUNT        12805 a         3654 c         6081 g         9603 t
ORIGIN      
        1 taaactatct cgcttaattt ctgatgtatc atggtcagag tttattcgtc aattagaata
       61 caaggctaat tggcatggta gacaaattgt aaaggtaggt aaattctttg caagttcaca
      121 aatatgcaat aaatgtgggt ataaaaacga ggaagttaag gacttaaata taagagattg
      181 gatttgtcct agttgtaatg aaactcacga tagagatata aatgcaagta taaatatatt
      241 aaaagaagga ttaagactaa taacaattca aaataaataa cttatgtaag aaccgtagga
      301 actacgggga tagcctgtgg agaattagta agacatattt tagtatgcaa aattctgtga
      361 agcaggaacc ctgtgacttt agtcatggga ggttcagagc tttaagttta ttgaagaaaa
      421 gaaaaaggaa ggaaaaataa agaatattgg tttttctttt catgatagtg cagaattatt
      481 ggataaagtc ttaagtgagc atccagaagt agacttcgtg caattacaga ttaattattt
      541 agactgggat aatgaaagca tacaatctag aaaatgctac gaggtggcac agaagcataa
      601 taaacctgta attgttatgg agccagtaaa aggaggtaca cttgcaaaaa taccagaaaa
      661 agcagagaaa ttattgaatg actacaattc agatatgtca attccatctt gggcaatacg
      721 ttttgcagca agtaaagata atgttatgat ggtcttaagt gggatgtcaa atatggaaca
      781 attattagac aacacaggat atatgcaaaa tttcaaacca ttcatacaag aggaatataa
      841 tattatagat gaagcagtag ggattatcaa cgaatcaatt ttagttcctt gtactgcatg
      901 tcagtattgt gtagaaggct gtccaaaaaa tatcgctatt ccaaactatt ttgcattgta
      961 caatgcagaa aaacaagctc ttaatactgg attttcaaca cagatggttt actataataa
     1021 ttatactaaa acttatggaa aggcttcaga ttgcattgaa tgtaaacaat gtgaagaaag
     1081 ttgcccacaa cacattaaaa ttatagatgc tttaaaaaat gtagcagaaa tctttgagaa
     1141 ataattcaat ctatacaata tcaagagggg aagatatata tgacaatttc agaagttagt
     1201 aaaaaatacg aactttcagc agatacttta cgatattatg aacgaattgg tttgatacca
     1261 cctgtaaata gaaataaaag tggaattagg tcttttacag aagaagattg tgagtgggtt
     1321 aatttcataa agtgtatgag aggtgcaggt ctttctattg agacattgat tgagtatgta
     1381 gctatgtttc aacaagggag tagcactata caagctagaa aagaactttt aatagagcag
     1441 agaaatcaac tagcaaaaag aatggaagaa atgcaaaaaa ctttggaacg attaaatttt
     1501 aagattgata gatacgaaga aggaattatt gagaaagaaa aagtattaaa gagcagtaga
     1561 aataagaaaa tggaggaagt atcttatgag taaacatgta ttgatagtat cagctagtcc
     1621 tagaaaaggt ggaaattctg atttattgtg tgaccagttt acacaagggg tattagaatc
     1681 taaaaatcaa gtggagaaga tatttttaaa agataaagat attaactatt gtactggatg
     1741 tggtgcttgt tataaaaaag aggcaagttg cccacagaaa gatgatatgg gagaaatcct
     1801 tgaaaaaatg attgaggcag atgtgattgt tttagcaact ccagtttatt tttatactat
     1861 gaatgcacaa atgaaaacta tgattgatag aacttgttct agatatactg aaatatgtga
     1921 taaagatttc tattttatcg tttcagcagc ggatgaaaat atagctgata tggaaagaac
     1981 aatagaagga tttagaggat ttacatcatg tttaaatggt tccaaggaaa aaggtatagt
     2041 atatggtgta ggggcttgga atataggtga tattaaggga agtgaggcaa tgaaacaggc
     2101 atatgaaatg ggtaaaatgg catagtatat ttgtataaaa tagaatatat ttttatcatt
     2161 tcaacaataa aaaagaggct tatctccatt ttgagacagc ctctttatgt tatatcattt
     2221 atttttattc tgtatccttt tatatcttct attttttgat gtctatttaa gtatctgttg
     2281 ttactcatat attttaataa ttacccttaa aaaactatac agattcctgc ataatattat
     2341 tctctttagt aattaatttt tctaggtttt tccaatcaat ttcttccata tttgcaaaat
     2401 aatgaccact tcctatgcaa gttaggtaag actttccatc taattcaaac gaagaaccac
     2461 caatacactt tgaattacat tttttacaag tacgagtttt agttatgcta tttttaatag
     2521 ttttagagca tttctccaca gcatccttat acgtatttaa atgaaaaaga tttgctttaa
     2581 ctctccattt cttttcatta cattcaatag taaataagct acgttttggc ttcttagttg
     2641 aatatactat tttgtaagaa cgagcacctg tctttggttc aattttacaa tctaatgatt
     2701 taccaagttc gtgtaaatga catgcaatat cataatcttt accacttagt acttctaaca
     2761 tttcttctgt tgtctctgct gttaattcac ttttgttcat attaaaaaat tccccctata
     2821 taaataataa tttcatataa aaataattaa tatcagtata ttaaatgaaa ttattaaaat
     2881 caatagaatt actataatct tacattattg ggcatagaat gagagctaat gatttatcag
     2941 aaataagact taatagtatg aaaatttact tagacgtggt acaattctat aaaagattta
     3001 aaactaggaa aggagaaagt tgttgagata tagccaatat aacaatttat ttatagattg
     3061 caaatttatt atgagattaa ttagattgtt aagtaagact attaaaaggt agtttttggg
     3121 attctcagca acagtggtag gatattgata attttttggt tactattata tttagctatt
     3181 atattttcga taggttctat gataactagg gtaaataagg tatgggtaaa ggttttatta
     3241 tttgtaatag tgggattgtc aactatagtt ctttcatatg taataacttg ataattttag
     3301 agtaaaaaac aactttaatc tggaaattct caaaacaaga attctcatgt tggtaaattt
     3361 ctagatatga gaaaaaattt gacattataa aaaagtaatt ttaaagcatt tttttacgaa
     3421 aaaattcaga agcaactatt ttgaatgact tcacaaaatt ttatatataa atgaagtttg
     3481 gcatgttaat tgctttaata aaagttaaca agacacaaat aaatataatc atctaagtat
     3541 tgattatttg aagttttaga tttgaaattt aatctaaaag ttcgtattaa tattggtgtt
     3601 taggaaattt tattttcctg taaatataac ttaataatag gaggtgaagt catgtcaaaa
     3661 gtagtaatag ctacagagaa agctccagga gcaattggac catattctca agcaattcaa
     3721 gttggaaaca tagtttctac atcaggtcaa cttccaatag atatgaagac tggcgagtta
     3781 gtatctgacc caaaagaagc aacaaaagct tctttagata atgtaaaagc aatattagaa
     3841 caagctggta caagtatgga taaaatattt aagactacag tattcgtaaa agatttaaag
     3901 gattttaatg atattaatga agtgtatgct acatatttta aagaaaatcc accagcaagg
     3961 tcatgtgtac aagttgctca attaccaaaa gatgcagttt tagaaattga agcaatggca
     4021 gtattataag tattataaca ataaaaccaa taacaaaact aatgaaaatt aaaaactaat
     4081 aaaaaaagtc tacaattaaa aaagtttata ttaaaaaagt ctatataaaa atctatctaa
     4141 atatttaact attgagcttt tctcatataa tgtatatttt tatgttaaaa atatatttgt
     4201 tatacgagga aagctttttt tattttatta ttgtattgtg atttatttta ttgtctgcat
     4261 attataatta agattactat ataaaacaaa ctttttataa attaatatca tgtgttttag
     4321 cgcaaatata taaataagta atgttttata tatattttaa agagtgacta tatgttaaaa
     4381 tatagctaaa ctgataattt ggtaaattaa attctaatgg gggaaactat gttaagtaaa
     4441 ttaaaagaat ttcaacaaga aatgataaaa tacactgaaa cagtagcgag tgtgttagat
     4501 gtagatattg aaatagttga tgatagatta ataagaatta gtggcacagg tctgtataaa
     4561 tcaaagataa atgaaagcgt tgttacagaa ggctttattt acgacaatgt tatacagaca
     4621 ggtcaggaat tagtcgtatt ggatatatgt gataatcagc tttgtataga atgttcccat
     4681 tacatgaaat gcctaaataa agtaataata gcagttccaa taaagtataa taatcgaact
     4741 ataggagtaa ttggtgctat tagtacagat aaaactaaaa aagtagaaat aagtgcaaaa
     4801 atagataatt atttaaaatt tgtcaatcat atatgcgatt taatttctat gaaaatagaa
     4861 gaacatgaag tgtcaaaaaa tagcagtaga aaaatggata tgatgataga aatcattgaa
     4921 aatgttgaaa aaggcgttat aatactagac ataaatagca aaatatctta tataaacaat
     4981 atagctctaa aaaaattaga tatagataaa aatataatag aaaatatagt aaatatagta
     5041 tctgttgaat cttcctcaaa tggacatgaa ttactagaaa ttgatattga taacaagatt
     5101 tataatataa atgccaaaat aattccagta tatccatata taaatcaata cgacaaaata
     5161 ataatatttg ataagacata tatcaatcat aaaggacatg taaaagttaa tagtggctgg
     5221 ggaaatagtg atatagagtc tataattgga aattcagaag caatgttaaa agtaaaagag
     5281 agaactaaga aattagcaaa gtcaaattca actgtactta taactgggga aagtggcacg
     5341 ggtaaagaac taattgctag agctatacac gctgagggta gtagatggaa taagccattt
     5401 attgcgataa actgcgctgc tattccagaa aatctccttg aaagtgagct atttggctat
     5461 ataaaaggtg catttagtgg agctagtagt ggaggtaaag taggtaaatt tgaacttgca
     5521 aatgaaggtg ttatatttct tgatgaaata ggagatttat caatgccttt acaagcaaag
     5581 ttacttagag ttttgcaaga gagaaaattt gcgagaattg ggtcaaataa acttatagat
     5641 ttagatataa gagtgattgc tgctacaaat aaaaatttat tgaaattagt aaatgaaggt
     5701 aagtttaggg atgatttata ctatagatta aatgtaattc ctataaattt gccacctctt
     5761 agggaaagaa aggatgatat tgaggcaata atgatgaagt ttgcttctaa atattcttta
     5821 gagttaggta ttcagttaaa taaaatagaa gaaaatgtaa tgaatatgtt gattaactat
     5881 aattggccgg gaaatataag ggaactggaa aatgcagttg aatatatgat gaatttggtt
     5941 ggagatgatg gaataatata taaagatatg cttccattgg atattttaaa ttattataat
     6001 attaatggaa acatttgtaa aaataaggat ataaatataa tatttgaaga tgacatagtt
     6061 ggaggaatag tagagaatca agaaaggata ctttcaatta aagaattaga gttgacttac
     6121 ataaataagc tgttgaataa gtatggaaga gatacgaaga cgaagaagaa aatagcaaaa
     6181 gacttaggta taggtttagc tacattatat aggaagttgg aagaagaaca gtcgtaatat
     6241 aatagaaaat taaaaccata aatctttata tattttaaaa ctaaataaaa tacacatata
     6301 attaaaatag aaataaaaca taaacttaga actaaataaa atataatcaa ataaaattac
     6361 agaaggttat agtcatatat ttatagaaaa taaaagtagt aatatatctg ataaaacaat
     6421 agacatataa aaaataagag cataataaag gaaaaattaa gacaaataaa cgatttctcg
     6481 aattgataat tctcgtattg ataaaaattt cccaatatga gaattttttc ttttataaat
     6541 cttgtttttt gcactcaaaa cttataaact ttaaagaaat tttataaaag tatgtaattc
     6601 caacataaaa aaattgtttt tagaataaat aatattggca tgctaattgc tttactataa
     6661 gacacaaaga taaaaaatta aaatgacatc gaaaaatttg aaaggggaat ataaaataaa
     6721 tgagagaaat aaaatggaaa ttaaataact tacctaaatc agaggaaaaa gaaaaaggaa
     6781 ttgaattttt aagagatgaa gagattgcaa aggctaaagc ttttcatgag agctttccac
     6841 aatacgaaaa gactccttta gttaaattag ataacttagc aaaatcacta ggcgtaagcg
     6901 gaatatatgt taaagacgaa tcttatagat ttggtttaaa cgcatttaaa gttttaggtg
     6961 gttcttactc tatgggtaga tacctagctc aaagattaga tacagacata tctgagctag
     7021 gttatgataa attaacttca gatgaaataa aagaaaagtt aggagaaata actttcttta
     7081 cagctacaga tggaaatcat ggtagaggag ttgcttggac agctaataaa ttaggtcaaa
     7141 aatctgttgt attaatgcca aaaggttctt ctgaatttag attaaataaa atcaaaggag
     7201 aaggtgcaga agctagtata acagacttaa actatgatga tgcagtaaga ttagctaatg
     7261 attatgcaga agctgatgac catggagtaa tggttcaaga tacagcatgg gacggatatg
     7321 aagaaatacc agcatggata atgcaaggat atggaactat ggctaaagaa gctatagagc
     7381 agttaaaaga atatggagta gatagaccaa cacacgtatt tgttcaagca ggagttggtt
     7441 cacttgctgg tgcagttcaa gggtatgttg cttcaatata tgatgaatgc ccaataacag
     7501 tagtagtaga ggctgatgag gctgattgct actataaatc agcagaagct ggagatggaa
     7561 aaccaagatt tgttggagga gatatgccaa ctataatggc agggcttgct tgtggagaac
     7621 caaacactat aggttttgaa gtgttaaaaa attattcatc agcattcgtt tcagcaccag
     7681 actgggtatc tgctaaaggt atgagaatat taggaaaccc tctaagagga gatgagaaag
     7741 taatctctgg agaatctgga gcagttacaa ctggagcatt agtttcaatc cttgaaagtg
     7801 aagatttaaa agacttaaga gaagctttga aactagatga gaactctaaa gtattattaa
     7861 taagtacaga aggagatact gaccctgata aatatagaga tatagtttgg aatggtgaat
     7921 gccaaagtaa ataaaagact taaggaaaag aaacatttaa caaataaaag aaaaatttaa
     7981 gcaaatgaaa aactaaagca aatgaaaaat tcaaaataaa aactaaataa aattaaaata
     8041 aagtctaaat aaaaatttaa taaataaaat ataaaggaat aaaaaatcaa tagattaagt
     8101 gaaatgctaa taaattaaaa aagtgaaata tcaaaataaa acgtcaacaa attaaaaatt
     8161 atatggggga atatcaaaat gttaaatgaa acaagaaaaa aacaattaac tgaagtatgc
     8221 caagacttaa taagaaatgc tagttattca ggtcaagaag aaaacgtagt aaaagctata
     8281 gaagagaatt ttgctttact aggttttgat agttggtcaa gagatagata tggaaatata
     8341 gtaggatgta taaaaggaaa taaaccaggt aaaaaaatat tatttgacgg gcatatagat
     8401 acagttccag ttccagatgc aagtaaatgg agtgttcctc cttttgaagc gagaatagta
     8461 gatgggaaaa tatatggtag aggaacttct gatatgaagg ggcaagtaag tgctatgatg
     8521 gctgctgttt catactttgc agaagatact aataaagact ttgaaggtga attgtacgta
     8581 gcaggtgttg ttcatgaaga aatatttgaa ggagtttcag ctagagagat aagtaaagct
     8641 gttcaacctg attatgttgt aataggtgaa tcttcagaat taaacttaaa gataggtcaa
     8701 agaggtagag gagaaatagt agtagaaact tttggtaaac cagctcactc tgctaatcca
     8761 gaaaaaggta taaatgcagt ttataaaatg gctaatgtaa tccaaaagat acaacaatta
     8821 gtacctccaa ctcatccagt tttaggtgat ggaatattag ttttaacaga tataaaatct
     8881 tctccatatc caggagcatc agtagtgcca gattattgca aagctacttt tgacagaaga
     8941 ttattagttg gagaaacaag agaaggagta ttagctccaa tacaagcttt attagatgaa
     9001 atgatgaaag aagacccaga attaaatgca aaagtttctt atgcagttga aaaagctgat
     9061 tgttacacag gaaatactat agaaagtgaa agattcttcc caggttggtt atatgacgaa
     9121 gaagatgaat ttgttcaagc agcgtataag ggactaaaag aagctggaat agattcagaa
     9181 ataactcaat attcattctg tacaaatgga agtcactatg caggtgaggc tggaataaga
     9241 actataggat ttggaccttc taaggaaaat cttgctcata caatagatga gtatatagaa
     9301 ttagaccaat tattcaaagg tgcagaagga tattatggta tattaaaatc agtttataaa
     9361 aaataattag gagatggttt tgtgagaact ttaataaaac atgggcttat agtagatgga
     9421 aataaaacac cagcatatga aggggatatt ttaatagaaa acgagaaaat attaaaaata
     9481 tcacaggatt taaacgaaga agctgataaa gttatagatg caaagggtag agttatatgt
     9541 ccaggtttca tagatactca tagccattca gacctagtta ttttagttaa tccatataat
     9601 gaggtaaaga ttagacaggg aattacaaca gaagtgttgg gccaagatgg tatatctatg
     9661 gcccctctac ctcaagagca tatatcttct tggagaaaaa atttagcagg tctagatggt
     9721 gaaagtgatg aaattgattg gaaatatgaa acaacagaga attatttaaa aatgatggat
     9781 gataacgggg taggtttaaa tgaaacttat ttagtacctc atggaaacgt tagaatggaa
     9841 gcaatgggac ttgaagatag acctgctact aaagaagaaa ttcaaaaaat gtgtgaaatc
     9901 acagagagag aattaaaagc aggagctata ggattgtcta ctggacttat atatatacct
     9961 tgtgcatact cattgactga agaaattata gagatgtgta aggtagtagc aaagtatgac
    10021 ggagtatttg tagttcacca aagaagtgaa gcagatacaa ttttaacatc aatggaagaa
    10081 atcatagaaa ttggaaaaca atcaggagta aaagttcatt tttcacattt taaggtttgt
    10141 ggtaaagcaa actggaagta tataccacaa gttatagagc ttttagaaaa agcagaaaag
    10201 gaaggcataa gagtatcttt tgaccaatat ccatatgcag caggaagtac aatgcttgga
    10261 gtagttttac ctccttgggc acattctgga ggaactgata agttaataga aagattaagt
    10321 gacgaaaatg aaagagcaaa aatgaaaaaa gatatagcaa atggaataga aggttgggat
    10381 aattttatag aatttgctgg aatagaccaa atatttgtaa caagcgtaaa gacagaaaag
    10441 aataaggatg taattggtaa gagtctatta gaaattggaa aaatgagagg aaaagaccca
    10501 ttagatgcaa cgtttgattt attaaaagaa gaagaaaatg cagttggaat ggtagatttc
    10561 tatggattag aagaacatat aataggattt atgaaaagag acgagcaaaa tgtgtgtaca
    10621 gatggtcttt tagcaggtaa accacatcca agagcttatg gttctttccc taaaatacta
    10681 ggaagatatg ttagagaatt gaatgtacta acaatcgaag aagctgttta taaaatgact
    10741 aaaaaagcag ctacaagctt tagtataaga gatagaggcg aattaaaaga aggatatttt
    10801 gcagatatag ttatatttga caaggataca gttagtggtt gtgatgattt tatcaactct
    10861 atgcagtacc ctacaggtat agattatgta attataaatg gaaattgtgt tgttgaagaa
    10921 ggaaaataca ataaaattaa agcaggaaaa gtacttaaaa attaaatctt agctttaagg
    10981 aggaataaat ttatgatttt agtggggaat gggaggctaa taagccaaga ttctttaaat
    11041 ccctatatgg aagatggatg tgtagtaata aatgataatc taattgaaga tataggtact
    11101 acaaatgaaa tgaaagctaa atatccagta catgaattta tagatgcagg taagaaaata
    11161 attatgcctg gtctaataaa ttcacatatg catatatata gctcatttgc tagaggaatg
    11221 gcagttccag gaaaaccttc tgagaatttt ttagagatat taaacaattt atggtggaga
    11281 cttgataaac agcttacatt agaagataca aaatacagtg catatgcaac gtatatagaa
    11341 tgtataaaaa acggtgtaac aacagtttat gaccatcatg caagtccaaa tgcaattgaa
    11401 ggcagtttgt ttacaatatc agatgttgca aaggatttgg gaattagaac atgtctttgt
    11461 tatgaagtat ctgatagaga tggtggaaat acaatccaac aaggtatcaa tgaaaacgta
    11521 aactttataa aatacgctca aaaagatgat acagacatga taaaaggaat gtttgggctt
    11581 catgctgcat ttacactatc tgatgataca ttaaataagt gtgcttcaga gatggctggt
    11641 cttgatacag gttaccatgt acatgttgct gaaggactag cagacttaca atataatgta
    11701 gataaatatg gaaaaagagt tttagaaaga ttcaatgatt ttggagtact aaaagaaaaa
    11761 acaatagcag ttcattgtat atatataagt tcagaagaaa tcagtctttt aaataaaaca
    11821 aatacatttg tagttcataa tccagaatct aatatgggaa atgcagttgg atgttctcct
    11881 gcaatagagt tattaaaaag gggtgttaca gtaggtctag gaactgatgg atatactagc
    11941 gatatgtttg aatcattaaa agttgcaaat ataatccaca aacatcattt aaaagaccca
    12001 agagttggat ttgaagaatc acaaacaatg ttatttgata acaatagaaa aatagcaaaa
    12061 gcttattata aaaatgacct aggagtactt aaaaaaggtg cttatgcaga tgttatagta
    12121 gttgattata taccacatac tccattgaca gaaaacacaa taggaggaca cactattttt
    12181 ggaatgagtg gaagaagtgt agatacaact attataaatg gaaaagtact tatgaaagat
    12241 agaaagttaa taaacataga tgaagaaagt attctagcaa aaagtagaga attaagtcaa
    12301 aatctatgga atagaattta aataattgat attaatatac aagtaagaaa caagaattta
    12361 gatgttaaaa gcagagctta aacaaaaata ggaatttaaa tgaagtatat gaataaaaaa
    12421 tatacggaat agaatattaa attaaatata gaagggagac ccaaaatgtc tcaagataaa
    12481 agccctaaaa tagctccagt agatgaaagg ttacctgtat ccaaatcttg ggtattttca
    12541 ctacagcacg ttttagcaat gtgtgcagga gcagtagcag ttcctatgat gataggaagt
    12601 gctgcacgac tagatcatgc tagtattgtt tttttaataa atgcttgctt gtttatggca
    12661 ggtataggaa cactcataca aagtgttggt ataggaaata ttgtaggtgc taaaatacca
    12721 gtaatagaag gaactagttt tgccgctgtg gcaggtatga cagcaatagc ctcatcatat
    12781 agtgattcac aagttgcaat acagacagta tttggctcag taatagtagc tggattgttt
    12841 tgtatactac ttgctccagt atttgaaaaa ctaataagat ttttccctag tgtagttact
    12901 ggaacagttg ttatggtaat aggtatttca ctatttccag ttgggataaa atggataact
    12961 gacaacaaat tggaagcggt tgaaccaaac tcattagcat tagctttagc agtattggca
    13021 ataactttac tttcatttaa attcttaaaa ggaatttgga atagcacagc tatattggta
    13081 ggtatagtac ttggtacact actttccatg gcagttggaa tggcagattt tagtgcagta
    13141 aatggagttg gttggcttaa cttaaatgta cctttaagat ttggaatgcc tagatttgaa
    13201 ccatctgcaa tactatcatt gtgtttaatt atgttggtac ttatgacgga atcagttggt
    13261 aatatgatag ctattcatga aatggtagac aaagaagtaa caggcaaaaa tattaaaaga
    13321 ggtctatttg gagatggaat atctacagca ttatctggaa tattcaattc atttccaata
    13381 actccattcg gtcaaaatac aggaatagta ggtcttacag gtataaaatc aagatttata
    13441 gcagtttacg caggggttat attgctagta cttggattct taccaaaatt tgcagcaata
    13501 ataggagcaa tacctaagcc tgttcttgga ggcgtaggat ttgcaatgtt tggaatggta
    13561 atggttggag gagtaaaaac tttaagcaaa gtaaaatttg atggaactaa aaacggggtt
    13621 atagtagcag ttagtgttgg tttgtctatg ataccactaa caaatcctga tttctatcat
    13681 aatttcccaa cttgggtaca aacaatattc cacagtggaa taacaacagg tagtttatca
    13741 gcagtgattt taaacatatt cttcaatgaa ctaggttcta aaaaagaaaa aaataacaaa
    13801 gttgaagaag caaagtaaaa ataagacaag taaaaatcta tatttattaa aagtcattaa
    13861 gcattgataa aagtaattca gagatattaa taattcaaca aaactatctt atattttaaa
    13921 taataaaaaa gtaaataaat aacgaataca aataaaaaaa tacaatctaa atattaaaaa
    13981 tatttaattt aagggagaga taatgatatg gctaatttaa aagttaattt atatggaatg
    14041 gaatttttaa acccaattat gacagcagca ggtcctggag caaaagatgg tgctctctgt
    14101 caagaggcag caaaaggtgg agcaggagct atatgtacaa aaactatatc tgtattacca
    14161 gctgatgtac caagaccatg tatggcaaaa actaatagtg gtttcttaaa cacagaatta
    14221 tggtcagagc ttccaaaaga gcaatggata gaagaagaat acaaaaaggt aaaaaaaaca
    14281 gggcttccag taatagtaag tatgggatat tcagcagagc aaatagctga ggttgctcct
    14341 ttagtaaaac cttatgcaga tgcggttgaa ttatctactc attatgtagg tacagatgtt
    14401 gcgccaatag taaatgcttt aaaagctgca aaagctgttt tagatgtacc agtatttatg
    14461 aaaatgagtc ctcatactga cattcaaact attgcaaaag ctgttgaaga agcaggtgca
    14521 gatgggcttg taatgataaa ctcatttgga ccatgtatgg caatagatgt aaatacagga
    14581 taccctataa tgggaagtaa agctggatat ggatggttat caggtgcacc aataagacct
    14641 ctagcaataa gatgtatata cgaagcttct caagttgtaa atataccaat aatcggtgtt
    14701 ggtggaatca cttgtggaaa agacgtagct gaaatgatga tggctggagc aagtgctgtt
    14761 caagtatgta cagaagcaat ccttaaagga ccttctatct atggaaaaat tgctaaagaa
    14821 ttaaatgaat ttttagatga aaatggatat gctgatgtta atgaaataaa aggattaact
    14881 cataagaaaa tgacagctag aggatttaga actcattcag tagctccagt agtggatgat
    14941 aacaagtgta tcaaatgtaa gcaatgtgta acaagctgtg tatatgaagc tttagaagtt
    15001 acagataagt tgaacataga tgcagacaag tgttttggat gtggattatg tgtaactaga
    15061 tgtccaaaag gagctttaag catctgctac aatcaagtag aagctatgaa tgagtaataa
    15121 ttatatagaa ttttggtaat taacttagag taataggtat taggataata aaatatatca
    15181 gataaacacg cattatgcat taataataca gtctaaagtt aataatttta tgatattgat
    15241 ttaactaaat attagtttag ctgaatatta atttaattag gtattggttt aatcttaata
    15301 tagatttact acgtataagt gaactaacta gattacttta agttaatttt ttcatataaa
    15361 ataaattgat acgttataag taaggtggag tctatatggg aattgtttta aaaggtggga
    15421 aagtagtaac aagtgaaaaa acttactgtg cagatgtaag aatagaagat gaaaaaatag
    15481 tcgatatagg tcttgatata tcaaaagaaa atgatgaaat agttgatgtt agtgattctt
    15541 atgttatacc aggaggtata gatacacaca ctcactttga cttagataca ggtgctacta
    15601 agacagcaga taactttgag acaggaacaa aagctgctat agtcggagga actactacta
    15661 tattggattt tgctacacag gctaagggat gttctttgaa agaagggtta gaagaatggc
    15721 atgaaaaagc taaggataaa tgctattcag attatgggtt tcatatggct ataacagact
    15781 ggaatgactc ggtttgtaat gaaatggaag atatggtgaa agagggagta tcttcattta
    15841 aattgtatat ggcatataaa ggaagtcttc aagttgatga tggtgtcata tttgaagcct
    15901 taagaaaagc agaagagata ggtggaatta ttggttttca ttgtgaaaat ggggatataa
    15961 tatgtgaact tgtggataaa gcaaaggcag aaaataattt atctccaaaa tatcatcaat
    16021 taactagacc agctatactg gaagcagaag ctacatcaag acttatgaag atagctgaag
    16081 ttgcaaactc taaagtatac gtagttcact taagttgtag agaatcctta gaggaggttc
    16141 taaaagctaa gcaaagaggt gtggatgtaa tagttgaaac ttgtcctcaa taccttctat
    16201 taaatgatgg attatatgat ttagatggat ttgaaagtgc taagtatgta atgtcaccac
    16261 ctttaagaga taaagaaaat aatgaaatat tatggaatgc tatttcagat aatcaaatag
    16321 atactatagg aacagaccat tgttctttta attatagggg acaaaaggaa cttggaataa
    16381 acgatttcag taagatacca aacggttctc caggtgtaga acacaggatg agtcttttat
    16441 acacatatgg agtctgtaaa aataaaatat ctatcaacaa gatggtagaa gtaacatcaa
    16501 ctaatgcagc aaagttgttt ggaatgtatc ctaataaagg agccatagaa ataggcagtg
    16561 atgcagatat attagtctta aatccaaaca aaaaatctaa aatagaagca aaaaaacaat
    16621 tacaaaatgt agattataca ccttatgaag ggtatgaagt ggattgtcaa atagaacatg
    16681 tttatttaag aggaaaagaa gtagttagag atggagaatt aatctgtaat actccaagtg
    16741 ggagatatat aaataggcgt ctaacaaagg gggctagaga atggtagaat ttatattaaa
    16801 tggagagaaa gttgttgcaa aagaaggcaa aaaactttta gacttcctta gagaagatat
    16861 gaatataact tcagttaaaa atggatgttc agaaggtgct tgtggaacat gtatggttat
    16921 aattgatggt aaagcgacta aagcatgtgt atttaaaact gataaattag ctgggaaaaa
    16981 cataacaact atagagggat tatcagagag agaaagagat gtttttgcat attcttttgc
    17041 tagtcaagga gctgtacaat gtggattttg tattccaggt atggtaatta gttcaaaagc
    17101 acttatagac gttaataata atcctactga agatgatata aagaaagctt taaaaggtaa
    17161 catatgtaga tgtacagggt atgtaaaaat aattaaggct gtcgatttag cagcaaagat
    17221 ttttagagaa aatatagatg tgccaaaagt aaactgtaaa ggtctagtag gtgaaaatct
    17281 tcctagagtt gatgcagtcg gtaaagcact tggatattct gaatatgtag atgatatgag
    17341 aattgagggt atgatttatg gttcagcagt tagagctaag tatcctagag ctttagttaa
    17401 aaaaatagat atagaagaag caaaagctta tccaggtgtt gttgcagttc taacagctaa
    17461 agatattcca ggaactataa aggtaggtca cttaaaaaaa gattgggaca ctttaatacc
    17521 agaaggtgaa ataactagat acttaggaga tggaatagtt ttagtagcag cagaaactag
    17581 agaagcgtta gaagaggcca aaaagctagt taagatagat tatgaggaat taacaccatt
    17641 aagtactaca gcagatgctc ttagagaaga tgctccaaag atacatgaga caggtaatat
    17701 acttgttagg gaacatttag taagaggaaa cgctgaagaa aagatagaaa attcaaaata
    17761 tgttgtaact aaaagataca ctacacctgc tacagaacat gcatttttag agcctgaatg
    17821 tgcagtagct ggtccttatg aagatgatgg agtaataatc tattcaacag accaaggggt
    17881 gtttgccact caacatgaat gtgcagatat gttagggttg ccatatgaga aggtaagagt
    17941 tataaacaaa atggtaggcg gaggatttgg tggaaaagaa gatatgagtg ttcaacacca
    18001 tgcagcttta cttgcatacc atactaagag atttgtaaaa gtacagttaa caagaaaaga
    18061 aagtattatt gttcatccaa aacgacatgc cacagaaatg gaatttacga cagcatgtga
    18121 tgaaaatgga tacttaacag gtatgaaggc aacgataata tctgatacag gtgcgtatgc
    18181 ctctcttgga ggaccagtgc tacaaagatt atgtactcat gcagcaggac catacaatta
    18241 tcaagatatt gatataacag gaacagcagt atatactaat aaccctcctg gaggagcatt
    18301 tagaggattt ggagttacgc agagttgttt tgcaacagaa tgtaatctaa acttacttgc
    18361 tgaaatggtt ggaatatcac cttgggagat aagatataaa aatgcaataa gacctgggca
    18421 agttttacca aatggtcaat ttgcagatga aggaacagca atagcagaga cactagaagc
    18481 tgtaaaagaa gagtatgaaa agcatccacg tgcaggtata gcttgtgcca tgaaaaatag
    18541 tggagttgga gttggtatac ctgatgttgg aagatgtaga ttggttataa aagatggcaa
    18601 agttcacata agaacaagtg cttcttgtat aggtcaaggg cttggtactg ttgtgactca
    18661 agtagtttgt gaaactgcta acctacttcc tgaaaatata gtgcatgaag ttccagatac
    18721 tcatttaaca ccagactctg gtaatactac ggcttcaaga cagacagtat ttacaggaga
    18781 agctactaag gttgcatcaa gtaagctaaa agaagcttta gactctggta aaactttact
    18841 tgatttagag ggagaggagt tttatggaga atatgaaagt attacagata aaatgggttg
    18901 tgacaaagaa aatccagtga gtcatgttgc ttatggatat gcaacacaag ttgtaatgct
    18961 agatgaaaat ggaagattgg aaaaagtagt agcagcacat gacgttggaa gagctataaa
    19021 tccaatcagt ttagaggggc aaatagaagg tggagtagtt atgggtcttg gatatgctct
    19081 aaccgaagat tacccagtag ttaaatctgt ccctacagct aagtttggta cattaggttt
    19141 atttaaatct acagatatac cagaaataca agctttaata gttgaaaaga acaaagattt
    19201 attggcttat ggggcaaaag gtgtaggaga aatttgtaca gttcctactg caccagcagt
    19261 acaaaatgcc tattatgtat ttgataaaga atttagaact gaactaccac tacaaaatac
    19321 tccatatagt aaaaaaaagt aacaaaaaaa agaaatatta aataaaaaaa tagatgaaat
    19381 tgtaaataaa aaaaaccctt ttgcataagg tatattttaa atgatagaat atacatatac
    19441 aggagggttt ttcttttata aaataagttt aataaaattg agaggtgagc agaatgaatt
    19501 ttaataatag tctagaatta actcagtctc agaagctaat aatgaccaca caacttaagc
    19561 aatcattatc aatattaaat atgagtaagt tagaattaga agaagagatt aaaagagaag
    19621 cagagaataa cccattggtt gaagttgaga agagtgggga gataaattgg gaagaatata
    19681 taaaagatat ggataggtca agacgtttag atagaacaga gataagctat aatcctgata
    19741 atgaagttaa tctagaaaat ttagttaaat attcgtcaaa tttatatgag gatttaaaat
    19801 ttcagataag cctgtataaa cttacagata aagaattgga agtctgtgag tatataattg
    19861 atagtttaga tgaggatgga tatttaagaa ctgaggaaaa agtaattgtt gataccttaa
    19921 agatagatga agaacttttt gaaaaatgct tgattagtgt tcagcagttg gaacctagtg
    19981 gagtaggggc aagaagtctt tcagaatgtc tgatgataca aatggctagt ttgggaatat
    20041 ataatgaaat tttagaggaa atcgttacaa aagacttaaa tttaattgca aataataaat
    20101 acaaagagat aagtaaaaag tacaatatgt cattacagaa atgcgttgaa ctaataaaca
    20161 taattaagac attagacccc aaaccaggaa gaacttgttc agtagagaaa agtgtataca
    20221 ttcaacctga tgtaacagta gaaaaaattg atgatgaatt tattgtatat ttaaatgaaa
    20281 aagattctta tcaaataaga atcaatagtt attataaaga catattaaaa aattcacagt
    20341 ctgatgaaag tgcaaaagaa tttataaaag aaagactaaa ttcagcaaca ggacttatga
    20401 aaaatataga gagtaggaaa actacagtac ttaagattgc agaagagata gtaaaagctc
    20461 aagatgaatt tttgagaaaa gggacaaaat atataaaacc tttgaaaatg aaagacatag
    20521 cagaaaaatt agaatttcat gaatctacta taagtagagg tgtaaatggt aaatatatgc
    20581 taacaccttt tggtgtatat gaatttaggt actttttcag tagtgccatt gagactgaga
    20641 ataatgaaat ggcatctagt acaagcataa aaaaaattat aaaggaaaca ataaaagacg
    20701 aaaataaaaa gaaaccttta agtgatgacc atatatcgaa gttactaaaa gaaaaaggaa
    20761 taaatgttgc aagaagaaca gttgctaaat atcgtgaaga attaggaatc ccatcttcga
    20821 gtaaaagaaa agaatactaa taagtaaaag acaaatatca gtatagtaag gggaaaaggc
    20881 taattaaaag atgaatgtgg attaggctaa aaattttatg aaataaaata ataaaatatg
    20941 gaaaagtatt aaaatgctat aagatattaa aaaactgggg aacattaaaa cattaaagaa
    21001 cattagagct ctaaggaata ttagaatttt aaagaagatt aaaatttaga aaatataaaa
    21061 atactaaaaa gagctgaaaa actggggaac attaaaatat tgtaaaatgc taaaaaatta
    21121 gaaaacataa ttaaataagt gcttataaag aatgattaaa ttaaataagt gtttgtaaag
    21181 aataattaaa tattagaaaa agaagaatac ctagataaat aaactattat taaatttaat
    21241 aatcacaaaa ggaaaacaca tagggtataa ataaaaattt tagctagaca gaagtaaact
    21301 tagctggaaa taaaagtaac tagaaataaa attatttata gtaataaata ttataacaga
    21361 aaatattaaa ataaaaaaat atatataaaa agccttatat aaaaagaaaa aatactgtga
    21421 tttgaaaatg gtggagaaat attttataaa ataaaaaaat aaaaaagttt ttgaaaaact
    21481 attgaaatct atacgcaaat cctataaaat aaaaatatct tgtgggactt aaataaacac
    21541 tagggacgaa aaaagtcccg aaaggaaagc aataaggagt atgttatgaa gaacttatta
    21601 gaaattcaaa agaaattgat tccacaggca attgaactta tggaaagaag atactctatt
    21661 ttaagacaaa tatctttaag tgaaccaata ggtaggagaa cattatcaaa tgtattagag
    21721 attagtgaaa gaataatcag gtcagaaaca gagtttttaa aagaacaagg acttatagac
    21781 gtagctgtat ctgggatgac tatcactaaa gaaggttctg atttgttaga taaacttaag
    21841 gacatcatga gtgacatcat gggattgtct aagttacaag atagagtcag agaaaagctt
    21901 ggaataaaaa gggtaatact agttcctgga agctgtgatg aaaatggaag tttattaaaa
    21961 gatgtaacta gatatggatg cgagtatttc ttaggtattt taaaagatgg agatatcgtt
    22021 tcaataacag gaggaagcac tatgttggag ttttcaaacg ttattaaaac tgataagaga
    22081 tacccaaatt ctacaatagt tccagctaga ggaagcatgg gaactgatgt agagatgcaa
    22141 tctaataaca tagttgcttc aataagtaag aaattacatt ctaattgcaa acttttacat
    22201 ataccagatg agttggatga aagtgcaatg aaaactctta gccaagtgcc agagattaag
    22261 acaactttgg agtatattaa aagaacagac attttagttt ttagtatagg tagagcagat
    22321 gtcatggcaa agagaagaaa acttccagaa gacaaagttg atgagatatt atctaaaaat
    22381 gcagttggag aagcatttgg atattatttc aacaaagatg gagaaatagt ttacaaactg
    22441 aatactgttg gaattgattt agaaacagtc aaacaagtaa aagaaactat tgcaatcttt
    22501 gcaggtactg aaaaagtaga agccttatta gccatatcaa atatgcataa aaacatggtt
    22561 cttgtaacag atgaagaaag tgcttataag atattgtcat cattataaaa gtcaagacct
    22621 agcacagagc tagaaaacat acatttactt tataggaggt agcgaaaatg gttaaagtag
    22681 ctataaatgg atttggaaga ataggaagat tagcattaag aaaaatgatg gagcaacaag
    22741 ataagtttga agttgttgca ataaacgact taacagacgc taaaatgtta gctcatttat
    22801 ttaaatatga tacagctcaa ggaagattta acggagaaat agaagttaaa gaaggtgctt
    22861 ttgtagtaaa cggaaaagaa ataaaagtaa cagcagaaag aaatcctgct gacctaccat
    22921 gggctgaatt aggagtagat atagtattag aatgtacagg attctttaca tctaaagata
    22981 aagctgaagc tcatatacaa gcaggagcta agaaagttgt tatatctgca ccagctactg
    23041 gagatttaaa aacaatagta ttcaacacaa acagtgacat attagatggt tctgaaacag
    23101 ttatatcagg agcttcttgt actactaact gtttagctcc aatggctaaa gtattaaacg
    23161 ataaatacgg tatagaaaaa ggattaatga ctactataca tgcatacact aatgaccaaa
    23221 atactttaga tggtcctcat ccaaaaggtg atttaagaag agctagagct gctgctggaa
    23281 acatagttcc aaacactaca ggagctgcaa aagcaatcgg tttagtaata ccttctttaa
    23341 aaggaaaatt agatggggca gcacaaagag taccagttgt aactggttca ataactgaat
    23401 tagtttgtac attaggaaaa aatgttacag ttgaagaaat aaatgcagct atgaaagaag
    23461 cttcaaacga atcttttgga tatactgaag aaatgttagt atcttctgac ataatcggaa
    23521 taagctacgg ttcattattt gacgctactc aaacaaaagt tatggaagta gatggaaaac
    23581 aattagttaa agttgtttct tggtatgata atgaaatgtc ttatacttct caattaataa
    23641 gaactttagg atactttgca caattagcaa aatagtcagt tttgagaaaa tagaaaagta
    23701 gattgacaaa gtccgagttt gtagtttaat actacggact caggactttt tttaagaaaa
    23761 aatatataaa atacacctaa ataatgttac atactatata taaaaatatg ataatatgat
    23821 atatttaata gggtaaaagt atgtactata ttatacttgg caataaaaaa ttactttatt
    23881 aaaaggagag atatttatgt caatgcttaa caaaaaaact atagaagata ttgatgtgtg
    23941 cggaaaaaaa gtattagtaa gatgtgactt taatgtgcca ttacaagatg gtgtaattac
    24001 tgatgaaaat agattgaacg gagctttacc aactattcaa tatttaattt ctaaaggggc
    24061 aaaagttata ttatgctctc acttaggaaa gccaaaagga gaagctaaac cagaattatc
    24121 tttagcacca gtagcgaaga gattatctga gatgttagga aaagaagttg tatttgcagc
    24181 agacgataat gttgtaggag aaaatgcaaa gaaagcaact gaagaaatgg aaaacggaga
    24241 tgtagtatta ttagaaaata ctagatatag aaaagaagaa actaaaaacg aagagaattt
    24301 ctctaaagaa ctagcatcac ttgctgaaat atttgtaaat gatgcatttg gaactgctca
    24361 tagagcacat tgctcaacag ttggtgcagg tgagttctta caagagagag tttgtggata
    24421 tttaattcaa aaagaactaa aattcttagg agaagctgtt gcaaaccctg taagaccatt
    24481 tacagctata cttggaggag ctaaagtttc tgataaatta gccgttataa atgaattatt
    24541 agaaaaagtt gataatctaa taataggtgg aggaatggct tatacattct taaaagctca
    24601 gggttatgaa gtaggtactt ctttacttga aatagacaaa gttgaatatg ctaaagaaat
    24661 gatggaaaaa gctaaaaata agggtgttaa cttattatta ccagtagacg ttgttatggc
    24721 agaccacttt gcaccagatg ctactccgat agtaacagaa gatgctaatg taaaagaagg
    24781 ttacatggga ctagatatgg gacctaagac tatagcaaac tttgtaaaaa ctataaaaga
    24841 atcaaaaact atagtatgga atggaccaat gggagtattt gaatttgaaa actttgcaaa
    24901 tggtacatta tcagtagcta gagctatggc agagctaact gatgcaacta ctgtaattgg
    24961 tggtggagat agtgcagcag cagttaatca attaggattt ggtgataaga tgactcacgt
    25021 atcaacaggt ggaggagcat cactagaatt tttagaaggt aaagaattac caggtattgc
    25081 agcattagat aataaataaa ctaatatata gaggagattg taaaatgaga aaacctataa
    25141 ttgcaggaaa ctggaaaatg cataaaacaa taaaagaagc tttagaattt gtaaatgaag
    25201 ttaaagataa agtaaattct gataaagtag aagctgttat atgtgcacca tttactttat
    25261 taaaggattt aaaagaagct actaagggta caaatataaa gataggtgct caaaatatgc
    25321 actttgaaga aaaaggagca tttacaggag aagtttcacc tcttatgtta aaagaaatag
    25381 atatggacta tgttgtaata ggacattcag aaagaagaca atacttcaat gaaactgatg
    25441 aaactgtaaa taagaaagtt ttaaaagcat tagaagtagg aatagaccca atattatgtg
    25501 ttggagaaac tttagagcaa agagaagctg gaaaaactaa agacgtttgt agagttcaag
    25561 ttgaaaaagc tttagaaaat gttcttaagg atgatttagc aaaagtagtt gttgcatatg
    25621 agccaatctg ggctattgga actggtaaaa ctgcaactgc tgaagatgct aatgacgtta
    25681 tatcttatat aagagaagtt ataaaaggat tatatggaga attagctaat gaggttagaa
    25741 tacaatacgg tggaagtgtt aaaccttcaa atgtagccga aataatgggt caaagtgata
    25801 tagatggagc tttagtagga ggagctagcc tagctagtaa tgattaccta gaccttgtta
    25861 atttctaagg agtgaaatga tgaaaaaacc agttgcttta attattatgg acgggtttgg
    25921 atacaataag gatgttaaag gaaatgcaat tgctgagtcc aaaactccta atttagatag
    25981 aataaaaaaa gagtatccaa acacattgat aaatgctagt ggtcttgatg ttggtctacc
    26041 tgatggtcag atgggaaatt cagaagttgg tcacactaat ataggtgcag gtagaatagt
    26101 atatcaggat ttaactagaa taacaaaatc tataaaagat ggtgactttt ttactaataa
    26161 agttttatgt gaagctatgg ataatgcaaa agaaaattct cttcatgtaa tgggactttt
    26221 gtctgatgga ggagtacatt cacatataga ccatcttaag gctataatca aaatggcaaa
    26281 agataaaggt gtacaaaagg tgtatgttca tgcatttact gatggtagag atactgaccc
    26341 tcaaagtgca ttagaatacg ccaaagaagt acaagctagt atggatgaaa ttggagtagg
    26401 tgaatttgct acagtttctg gtagatacta cgctatggat agagataaga gatgggaaag
    26461 agtagagctt gcatacaatg ctatggttag aggtattggt gaaaaagcaa cttctattga
    26521 agaagctatt caaaactctt atgatgatgg aaaaaatgat gagtttataa tgccaacagt
    26581 tattatgaaa gatgataaac cagttggaag tataaaggaa aatgattcaa ttatattctt
    26641 caactttaga ccagatagag ctagacaaat aactagagct ttagtttgtg aagagtttga
    26701 tggatttaaa agagaagata ttaaaaactt ctttgtatgc ttaacagagt acgatataac
    26761 tatagagaat gtgcatatag catttggacc tcaatcttta gccaacactc taggtgagta
    26821 tctagctaaa aatggaaaaa ctcaacttag agctgctgaa actgaaaagt atgcacatgt
    26881 aactttcttc ttcaatggtg gagtagaaga gccaaataaa ggtgaagaaa gactattaat
    26941 accttctcca aaggttgcaa cttatgattt aaaaccagaa atgtcagcat atgaattgac
    27001 agataaagct ttagataaat taggagaaga taagtttgac tttatagtat taaactttgc
    27061 caatcctgat atggtaggtc acacaggaag tatagaagca gctgtaaagg ctgttgaaac
    27121 tgtagacact tgtgtaggaa aattgataga taaaatagta gagttaggtg gaagtgcaat
    27181 aataactgct gaccacggaa atgctgaata tatgttagac ccagaaacag gaaaaactgt
    27241 aacagctcac tctattaatc cagtaccatt tattgtagtt ggtcaagaat atgaaaatgc
    27301 aaagttattg gatggaggaa gattatctga tatagcacca actgttttag atatgatgaa
    27361 gttagaaaag ccagaagaaa tgactggtca ttcacttatt tcaaaatagt cgattatgat
    27421 aagtataaaa taagatataa gctacaatat aaatttaaaa ataacacagt ttaggtttat
    27481 tttgtaaggt ctagatttta tgatataaga tttagctttt gtaaggtctg gatattgtaa
    27541 ggtgtagatg aaagtatatt ttataatatt tacaatatag acaatttata aaataaaaaa
    27601 ttataatata gataatgata taaataataa tgtaaataat aacaatatag acaataacaa
    27661 tataaataat aataattaat atatattata taagcaaaaa ttttagaatc attagttgta
    27721 cattttatgt ttaatgtttt aaatctagtt ataatattcg tgtatttaag attggttttg
    27781 gattttagac aagttttttt atattatata aattaaaata ttataaaaaa taaaataaaa
    27841 ataggaactt ttacaaattt acccatcaaa taaatttgta cctaattttc aaaagcaact
    27901 ttatgtacta taatatagaa agtagattaa aatagtagac ggatgtttac agtaaatgaa
    27961 attttaacta atagaaaatc gaagggagat atacaaatgt cagttattga attagtatat
    28021 gctagagaag tattagactc aagaggaaat ccaactgtag aagttgaagt agtattagaa
    28081 gatggagcaa tgggaagagc aatagttcca tcaggagctt ctacaggagc ttttgaagct
    28141 gttgaattaa gagatggaga taagggaaga tacttaggaa aaggtgtaga aacagctgtt
    28201 gctaacgtaa atgaaataat agcacctgaa atagaaggaa tggatgcatt tgaccaacca
    28261 gctatagatg caatcatgat agaattagat ggaactccaa acaaaggtaa attaggagct
    28321 aatgctatat taggtgtttc aatggcagta gctagagcag ctgctgatga aataggttta
    28381 ccattattcc aatatttagg tggagtaaat gctaaacaat tacctgttcc aatgatgaac
    28441 atattaaacg gtggagagca tgctgataac aacgttgatg ttcaagaatt tatgatatta
    28501 ccagtaggag cttgttgttt caaagaaggt ttaagaatgg gagcagaagt attccattca
    28561 ttaaagaaag ttttaggaga aaaaggatta gcttgtggtg taggcgacga aggtggattc
    28621 gctccaaact taggttcaaa cagagaagct ttagaattaa tagttgaagc tataacaaaa
    28681 gctgggtata agccaggtga agatgttatg ttaggtcttg acgttgctgc tacagaaatg
    28741 tacaacaaag aaactaaaaa atacgtttta gcaggagaag gaaaagagtt aactgctgct
    28801 gaaatggttg ctttatatga agattggtca aacaacttcc caataataac tatagaagat
    28861 ggtttagatg aagaagattg ggatggatgg aagttattaa ctgaaaaatt aggaaataaa
    28921 ttacaattag ttggtgacga cttatttgtt actaacacag agagactaga aaaaggaatt
    28981 gaaaatggag tagctaactc tatattagtt aaagttaacc aaataggtac aataactgaa
    29041 actttagatg ctatagaaat ggctaagaga gcaggatata ctgctgttat atctcataga
    29101 tcaggagaaa ctgaagattc tactatagca gatttagctg ttgcagtaaa tgctggtcaa
    29161 ataaaaactg gtgctccatc aagaactgat agagttgcta agtacaacca attattaaga
    29221 atagaagaaa tggttggaga gcaagctaga tactgtggat taaaatcttt ctataactta
    29281 aaaaaatagt tattaagatt aaagaaatag tataaaacgt ttaagtttgt cttatataag
    29341 gataagtgtt agttgatttt tcaattcact tatccttttt tatatattat tacctaattt
    29401 tattcacagc ttgagaaaaa atatgaataa atgtttctat ctcaccttta tctaattgat
    29461 gtaggatatt tttaaataca gttgcttcta tttctctatg ttctttttga gcttttaaac
    29521 ctaattcagt taaatctaaa ttatacgccc ttttatcctt aaagcaagga tttctattta
    29581 taagtttttt agctcaagac gttttacatc acttgttaat gtgctttttg gaaattctaa
    29641 agttgaacta atttctttta tcatactatt tggatgttgc tcgactattt ctaaaatact
    29701 taattctact aaagaaatac cagaaatagt aggatattta ccactacaca tttctgtttt
    29761 catttgtata ccaacgttgt gccataggtt gcttagttct tttatagcat tcattgacat
    29821 ttacctccat ataatacgat tatcgtacta atataatatg atagtcgtat taatttgtaa
    29881 ataggatggt tttttatgaa tttagatatt tccgtccagc gttttgggga acgcctgttg
    29941 caaaaaaagg attacaattt tgtattgatg gattaagaaa tttaggatat ccatatataa
    30001 caatatgggt tctaaaagat aatattagag ttataaaatt ctataaaaaa atggttttac
    30061 ttgtgatgat tttgagaaag atatatgtat tggaaaaaaa ttattagaaa tatgttacct
    30121 aaaaaagaca cagtaattat atattttttt gtatgtgatt tatagcataa tagtcttgaa
    30181 atggctatat tattgtgata cactaaagag taatgaaatt taagtaataa acagatagga
    30241 ggggcaagaa tgagcaacat tttaatgggt gtgcaagtag tgctagggat tttactagta
    30301 attagcataa tgcctcaaga ttcaaaaaat gctttacctt cagagtttgg tggagaggga
    30361 agtcaagctt actttaaacc aaaagggaaa caagcatttc ttgctagagt tacaaagata
    30421 acagcagtat tattttttat aaatgcattg gcattactta tagttaagaa gtagtgatat
    30481 tgttgaataa ctggccatta tttaattagt gcatttgcta gacatttaaa aattaaattt
    30541 agtttttaat aaaagtaagt caacataaaa aatacgtaaa ataaaagctg gactaatgat
    30601 tttatatgat tagtccagtt tttattttat agattgacta tctattaata tctattgttt
    30661 gtatttatat attttttaaa tcaagcaata aataacaaca gtactttcaa catgtttcac
    30721 aagataatat acataaagtt atatagtaaa aatagtataa tcatatgttt ttatgtaact
    30781 aaatcaattt tatatatgtt tctcataata ctaatttatc ctattgcata tcattaaata
    30841 agattattct gttttaaaat aaatattatt aaaaatactg taattataga aaatgcagaa
    30901 gtaaatacta caatttgtcc agctaattca ctatcagaat ccatctgttg tgacattgta
    30961 aatgaagaaa ctgcagttgg agcagataac attatcataa gtgaagctaa ttctacattt
    31021 ctaaatccaa gaaaaatact aattggcaaa aatatagcag gtacaagtat aagttttcca
    31081 cataccccaa atataatagg ttttatatgt ccttttatag cagaaaaact aaaagaacct
    31141 cctagaatta taagcgataa aggagtagct atcttagaaa tatcaccaat agttttgtgt
    31201 aaaaatgtag gtatattaat atttaaaatg agcattgtca atcctataaa agaggcgatt
    31261 atgagtggat ttgttaaaac acttttaatc atatgtttta tatttacttt gcctcctcta
    31321 aaaatttcaa gtattataac agataataca ttaaacatag gtacaataac tgcaatcaat
    31381 aaagatgtga caccaatact cttatcacca aatagtgaaa ttgtcacagg aataccaaat
    31441 ataacgaaat tactacgaaa tatgccttgt attaatgcac cccttgtctt attatttttt
    31501 tcaattttag gaataataaa gactaagatt aagaagattg aaaaaataat tataacagct
    31561 acagccataa gtttaaaatt aagagaacca tctaaatctg tattgtatat attaaaaaat
    31621 aataataatg gcaagaaaga cttgaaacag acattattca ttttatttaa agtatggaca
    31681 tcaaatagac ctaatttttt tagaacatat ccaagtgaca ttgtgagaaa caaaggaaga
    31741 acaacattta ttgataggat taaattttcc aaggtttact ctccaggatt ctatgattcg
    31801 ataattcaat taaatttacg tcagtttttt taaaacaaat agatttcata ttactaaaga
    31861 cctctgtaca ctctacaatt actcgcttaa tttgaatctc attttgttct aagtattttt
    31921 ttggctcatc aatatttgta tctattttaa agcataaatt agtactgatt gtttgtacat
    31981 tttcaccttg tggtaaaaat tcatgacctt ttatgtttag atttatctta acatttccag
    32041 cattaaattt atatttttca cttgtttcct taaatgaaaa accaaatttt ttataaaaat
    32101 ttatgtaatt ttctatatta ttagtagtaa tgagtacatg ttt
//
LOCUS       DBGJFK010000040        31596 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.040, whole genome shotgun sequence.
ACCESSION   DBGJFK010000040 DBGJFK010000000
VERSION     DBGJFK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31596
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.040"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(165..1016)
                     /locus_tag="ACOIAP_002182"
     CDS             complement(165..1016)
                     /locus_tag="ACOIAP_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HGZ2639065.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHYFEQGTKIKVSYSGGVFKSGDLILESLKKY
                     LNKARFD"
     gene            complement(1126..2040)
                     /gene="murQ"
                     /locus_tag="ACOIAP_002183"
     CDS             complement(1126..2040)
                     /gene="murQ"
                     /locus_tag="ACOIAP_002183"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HGZ2639066.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAVEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVEYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKNILDRQEGYISEALKSIERL"
     gene            complement(2139..3236)
                     /locus_tag="ACOIAP_002184"
     CDS             complement(2139..3236)
                     /locus_tag="ACOIAP_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HGZ2639067.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKVAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKMKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEVNMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKSTERFNKYGLRTAVFVTSQNESTFGPWPITDGLPTIEIHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DNLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(3469..4815)
                     /locus_tag="ACOIAP_002185"
     CDS             complement(3469..4815)
                     /locus_tag="ACOIAP_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGZ2639068.1"
                     /translation="MLDKFTEFLDIKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYIKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKVVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEVY"
     gene            complement(4905..5213)
                     /locus_tag="ACOIAP_002186"
     CDS             complement(4905..5213)
                     /locus_tag="ACOIAP_002186"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639069.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGTKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKGFADEVGVPCALIKAQAYSPLGGPKLLKQVQELLSE
                     "
     gene            complement(5480..5869)
                     /locus_tag="ACOIAP_002187"
     CDS             complement(5480..5869)
                     /locus_tag="ACOIAP_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639070.1"
                     /translation="MSNNKKKKNNNYKNAKITKSNKNTKREMEKNQKTDYNIPTISFK
                     SGLILIVSSLVSTVIFPVLLSIFGIDNRLGVIIGNSLITSFAVAYTRYFIETKRGFSL
                     GFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(5871..7022)
                     /gene="anmK"
                     /locus_tag="ACOIAP_002188"
     CDS             complement(5871..7022)
                     /gene="anmK"
                     /locus_tag="ACOIAP_002188"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase AnmK"
                     /protein_id="HGZ2639071.1"
                     /translation="MYSVGLMSGTSLDGVDAVLAEISGSGRNTKIKQIEFITLEIPKD
                     IKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCYKANFNIENLDFIASHGQTI
                     FHIPRSYNNFVSSTLQIGEPAVIAHETNTKVISNFRVMDIAAGGEGAPLVPYSEFLLY
                     SDNNKNVALQNIGGIGNITIIPKSCNIEDVFAFDTGPGNMIIDGVCQKLFNKRYDKNG
                     YFASKGKINEEMLKDLMSHKYLSQSPPKSTGREIFGQVYLDNMLNKYKHVDKYDLIAT
                     VTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIRYIKELLLGVEVLTQDEYG
                     YSSDAKEALAFVILGNETLNNSFSNVISATGAKSKVILGNITPKPFGGK"
     gene            complement(7451..8470)
                     /locus_tag="ACOIAP_002189"
     CDS             complement(7451..8470)
                     /locus_tag="ACOIAP_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGZ2639072.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNRYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYINLYNCIEDSGEIDSYLVDGQSFEENLIKDIIENLK
                     MKNNSDIESYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSNIEDSLDIKNQIAKI
                     NFLVNSILYSSRSNTMFEDLFVNKFNLDKMVRMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYILEQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGLYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LNLDS"
     gene            complement(8464..9144)
                     /locus_tag="ACOIAP_002190"
     CDS             complement(8464..9144)
                     /locus_tag="ACOIAP_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639073.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEIVLDEFVDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIDILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(9296..11203)
                     /locus_tag="ACOIAP_002191"
     CDS             complement(9296..11203)
                     /locus_tag="ACOIAP_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2639074.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPIIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMNRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSKVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMVSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(11204..11956)
                     /locus_tag="ACOIAP_002192"
     CDS             complement(11204..11956)
                     /locus_tag="ACOIAP_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639075.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPAVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(12274..13428)
                     /locus_tag="ACOIAP_002193"
     CDS             complement(12274..13428)
                     /locus_tag="ACOIAP_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2639076.1"
                     /translation="MINKAIKFRFIIFYFLSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDKINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTSKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYNSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSVNIGYNYTLMVLSLFGCLAYGLIVLLNYLKE"
     gene            complement(13431..13898)
                     /locus_tag="ACOIAP_002194"
     CDS             complement(13431..13898)
                     /locus_tag="ACOIAP_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGZ2639077.1"
                     /translation="MFFKRKKEVITINSYIDGRIINLEEIPDKVFSTKVMGDGFAMIA
                     KDNALKSPAKGVISFIAQTNHAIGIKLQNNVQILIHIGLDSATTKKENFKLKVKQGQE
                     VNMGENLVEIDNKLLENTLYIPLVIIENPNTVKYHLSNLHQEGNSGIKVINFD"
     gene            complement(13912..14400)
                     /locus_tag="ACOIAP_002195"
     CDS             complement(13912..14400)
                     /locus_tag="ACOIAP_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639078.1"
                     /translation="MITNKIKNVTAVLKDENIFLSVIMGCFLILPVLYIVYLELTSLF
                     TNISFSELLNNDVNASLNLVSNFSAVYSAYVIYNLKKNKDIKENMIAFYLVLLGQIFQ
                     IYTLTIVIMFTYVYKFVGIKQIISSIKELQWGKSYKALFSSVAVCLISLFIMIIRIKL
                     IM"
     gene            complement(14414..15745)
                     /locus_tag="ACOIAP_002196"
     CDS             complement(14414..15745)
                     /locus_tag="ACOIAP_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HGZ2639079.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVDKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGVAYGLRTIGPVIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(15759..17324)
                     /locus_tag="ACOIAP_002197"
     CDS             complement(15759..17324)
                     /locus_tag="ACOIAP_002197"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucoside-specific PTS transporter subunit
                     IIBC"
                     /protein_id="HGZ2639080.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYVHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHVQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFAAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFIAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYIIQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDTEETKLYTKNEYLEAKDEKGNKLSKASQQAAE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(17493..18278)
                     /locus_tag="ACOIAP_002198"
     CDS             complement(17493..18278)
                     /locus_tag="ACOIAP_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGZ2639081.1"
                     /translation="MRLEEMIFLNYNKLNETDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(18443..19642)
                     /locus_tag="ACOIAP_002199"
     CDS             complement(18443..19642)
                     /locus_tag="ACOIAP_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HGZ2639082.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLENKDEYIKRIRSTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKEVVDRYDSMNPKIKMPDDIFVKKELILKDVIKG
                     KIGYMYLPSMSSKNGSINNDLKIIGDYISTLKKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTTARNIKLNPVESLPASVKENAPKEIIKDFNGFE
                     DTSYTIKSTDDLKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKSGVCDEEFKTTPEFKVKDCKRTADFKEDNCIRKAL
                     EFENINY"
     gene            complement(20164..21501)
                     /gene="xylA"
                     /locus_tag="ACOIAP_002200"
     CDS             complement(20164..21501)
                     /gene="xylA"
                     /locus_tag="ACOIAP_002200"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009045 - xylose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HGZ2639083.1"
                     /translation="MNEIFKGIGQIKFEGVKSNNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKANMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKVNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(21605..23152)
                     /gene="xylB"
                     /locus_tag="ACOIAP_002201"
     CDS             complement(21605..23152)
                     /gene="xylB"
                     /locus_tag="ACOIAP_002201"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HGZ2639084.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDSEGKTLRKSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEVTG
                     YVTKDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLDEDVYDIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDTIIKTSTKLEPISENVDIYKTYHRLYKKIYKSLKDDFRLLDE
                     AVNCKNK"
     gene            23360..24520
                     /locus_tag="ACOIAP_002202"
     CDS             23360..24520
                     /locus_tag="ACOIAP_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGZ2639085.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSMSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHDSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKKLYYEDNQNTKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(24676..25080)
                     /locus_tag="ACOIAP_002203"
     CDS             complement(24676..25080)
                     /locus_tag="ACOIAP_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2639086.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTNELVVKLEKIGKDNISMVEQNTSLLSDDE"
     gene            complement(25101..25583)
                     /locus_tag="ACOIAP_002204"
     CDS             complement(25101..25583)
                     /locus_tag="ACOIAP_002204"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639087.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKM
                     HNINVGNMSSRKDTTVLKPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(25603..26412)
                     /locus_tag="ACOIAP_002205"
     CDS             complement(25603..26412)
                     /locus_tag="ACOIAP_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGZ2639088.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIIVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(26405..27184)
                     /locus_tag="ACOIAP_002206"
     CDS             complement(26405..27184)
                     /locus_tag="ACOIAP_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGZ2639089.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQAQQYTVVGGMDEDE"
     gene            complement(27184..29262)
                     /locus_tag="ACOIAP_002207"
     CDS             complement(27184..29262)
                     /locus_tag="ACOIAP_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGZ2639090.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     KFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEIECPLEEIPIFLKQDSSYNFKE
                     LKNILSEVKS"
     gene            complement(29870..30037)
                     /locus_tag="ACOIAP_002208"
     CDS             complement(29870..30037)
                     /locus_tag="ACOIAP_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639091.1"
                     /translation="MTGYVANISQTSQALCGIRSINGIIPIVLTVAMLVQMYSLAERK
                     CREVINELRSK"
     gene            complement(30208..30729)
                     /locus_tag="ACOIAP_002209"
     CDS             complement(30208..30729)
                     /locus_tag="ACOIAP_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3072 family TudS-related putative desulfidase"
                     /protein_id="HGZ2639092.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPYVRQFGEYLKNNYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCSELMDKINDIQMVEGKGIFIEELEKLLKEYNLE
                     IPIVGFDEIREGK"
     gene            30895..31461
                     /locus_tag="ACOIAP_002210"
     CDS             30895..31461
                     /locus_tag="ACOIAP_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3073 family putative ECF transporter S
                     component"
                     /protein_id="HGZ2639093.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISNKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTYSHS"
BASE COUNT        10388 a         5602 c         3323 g        12283 t
ORIGIN      
        1 gtttatttca tccttatgtt ttagtttggt tagctttagg ggtttttagc aattcaagta
       61 gtattggata ggtgttatcc tatctctaca tataagtttc cctatatgct gactatttta
      121 gctactaact catgactaaa gtcacaagta tgcgtagcta ttttttaatc aaatctcgct
      181 ttattcaaat attttttaag tgattctaat atcaaatctc ctgacttaaa cactccacct
      241 gaataagata cctttatctt tgtaccttgt tcaaaataat gctctaatcc tattataagc
      301 ctacttaatt cataagctgc atcatcaaat attttactag cagtattatc accttcaata
      361 actgctttta aacatatcgt agcaaacttt gctatttcta ttctatctcc ttgtatttca
      421 tcatttacat attttattat gtcataatca ttctctatat taagatgtct ttttattaaa
      481 tcatataatt ttgtttttga acaccttcca tcagactgca ttgtgaacat ttttagggta
      541 gccattccta tataatatgc tgacccttca tctcctaata catagcccca tcctccacat
      601 ctgtgaagat tcccatcttt atctaaagcc tgtgctattg aaccagtacc tgcaattata
      661 tttatacctt tttccccatt taaagaacct gctaatgcta tttctacatc attacctaaa
      721 gtataattta tatggctata tgcatttttt gttgctactt ctaatgcata caatacttct
      781 tttatttttc catatccagc aagtccaaca aatgcatacg ttatttcttc tacatttatc
      841 ttagcatctt tacaaacttc ttccaaccca gttattaata atttcgttag attatcaaat
      901 cctatttgat tataatgaca agttcctttg gttatggttc ctactatatt taattcttca
      961 tctactaatg taaatgttgt tttcgttcct ccaccatcta cccctaaaaa atacatacta
     1021 tcctcctaca atatttttaa taattctttc aatacttaat atctaaaaat aaccttccaa
     1081 tgcagttctt ttaatattga aaggttatca gtattattat ttattttaca atctttctat
     1141 tgattttaaa gcttcactta tataaccttc ttgtctatct aggatattct ttgcactatc
     1201 cttatctaaa ccacttttta tcataaatat agccaattta acgctattat ctgcttcttc
     1261 taagaatttt tctgcaacgt catattctac atttgtagct atcattatta ttctttttgc
     1321 tctttcaacc aacttttcat ttgatgtctt aacatctacc atcaagtttg agtatacttt
     1381 tcccatctta accatagaag ctgttgtcaa catattacat accatttttt gagctgtacc
     1441 acttttcatt ctagttgaac ccattattac ttctgcccct actataatgt ttattggtaa
     1501 atccgctttt ttactcattt cactattcgg attcatagtt attgatagta ctgcacaccc
     1561 taattcctta gcatactcca ttgcacctat cacataagga gtccttcctg atgcagctat
     1621 accacatata acatccttag atgtaactcc tctatctatt atatcttgtt ttccaagttc
     1681 tttatcatct tcagcacctt ctactgcttt aaatattgct tgatttccac cagctattat
     1741 agcttgaaca agctcaaaat ccactccgta agttggagga cattctgtgg catctagtat
     1801 ccctattctc ccactggtac ctgctcctat atagaataat ctacctccct gcttcattct
     1861 atctactatt atattaacag cttttgctat actctccttt tgttcttcaa cagcataggc
     1921 tacagtttta tcttcgttat ttattaattc tattatgcct aatgtatctt ctttatctat
     1981 ttgcaatgta ttcttatttc taccttctgt aactaagttt tctaaagttt ttattaacat
     2041 atcatttcct cattttctta atattaaatt tttaaacaca ttttaattcc aaccttcatg
     2101 attatatcta cataataaat taatattttc ataataaatt attttgttga aggcttaaaa
     2161 ttaaactttt gccatggttt aatgtaatct aatataaata attcttcttt tcttatatat
     2221 cctactacat tcgatttacc actgtttttc atatcagtca aagctatttg taactccccc
     2281 gcataatgac catattcact actttcaatt actatatctc ctctttttat tattttagga
     2341 gtattaaata gttcgaattt gtatccttta tatttaacac gagattgagt agaccttatc
     2401 agattatcag atatatcccc tctattaaaa tgtatttctt caaagagtat cttcttctca
     2461 acttctcgta tattttcctc tattgctaca tcaaatgtaa ccatatcttt tctcatagaa
     2521 cctaatacct taagctcctc atatgttgga taacaatttg atattattat atcatttata
     2581 ttattcatag ctattatatg ctttacttga atatctatag gtagatttct gtgaatctca
     2641 attgttggaa gtccatcagt tataggccat ggtccaaatg tactttcatt ttgacttgtt
     2701 acaaaaactg ctgttcttaa tccatactta ttaaatcttt ctgtagattt tataaagtgt
     2761 tctaaattta atccactata tctgtgtgga taaaagttat gacatcctat caaattctct
     2821 ttgtttggtt ggtagtccat tattgtatct atataattag tattgttact catattgact
     2881 tctattttaa ggttctgagg attaaaagtc attaatgcct cttcagaccc tgtaaatccc
     2941 atatcaagcc ttattccatc tgccttcatc tttttaaaaa aagtcaaatc tttgtagctt
     3001 atttctaatt caccaaatac tctgggattt acatcaagta ttacctcaaa acctttaaac
     3061 ttagcgtatt cgtttatact tttaaatttt ttaattatat tttctttagt atctttaact
     3121 gataataaac atgaaaatat acgtgtaaat ccattttcag caaccttatc tatataatca
     3181 tatatttcct tagatgttgt tttttctgga taaattgata ttcctaatct tcccatctgt
     3241 gtcatctcct tatatcctat atgtgtttaa atttatttag aattacacga aactttttta
     3301 aaaatttggt gaaaaaaagt ttcatatata tttataaaaa aagaaaagtt taccttttct
     3361 ttttttataa acaatcaaca aaatatcttt gttacttatt tcataactgt tatactttga
     3421 aatttatact aatctaatat agtttttaat tttcaatata gtttctaatt aataaacttc
     3481 ttgctcttca actttttctt catgaagcaa cctcttatcg tacatcttga caaatggata
     3541 gtaaattatt attgatatag ctatacataa taagttgaga actgaagctc tccaatctcc
     3601 accagtggct aaatatgccc ctactggtcc tggtaatgtc caaggagcag taactactac
     3661 tctagatact aaattagcac tcatagcaaa ccacgaaact gttgccatta ctattggtgc
     3721 tacaacaaat ggtattatta atattgggtt taatactatt ggtgctccaa atattattgg
     3781 ttcatttata ttgaatattg ctggtattac agttgctttt cctaaagact ttccataagc
     3841 tgattttgct ctaaatgcaa gaagtaaagc taagcctatt gtagctccag aacctccaat
     3901 ccatataaac cattgaaaaa atggttcagc agcaatacct ggaactgctt gacctgcagc
     3961 atatgaagct gtattagcat ctaataattg tatccataaa ggtcttgcca atgaacctat
     4021 tattgataca ccatgtattc caaatgacca aaaaaacgtt attaaaaata ttagtataat
     4081 tactgatggt aatgtgtcag tggctgaaac taatggagtt actagtttag ctatgaaacc
     4141 atgccaatca aatcctagga aataagtaac aatagccatt aaaattatta ttaatgcagc
     4201 tggtgtcaga gcttcaaaag accttgtgac tgatgctggt actgcttctg gcatggttat
     4261 cttgaactta gatttgtcag taaatctata aatctcaaca cctattatag acgttacaat
     4321 agcaacaaac attgaacctc caccaagatt agccattggc atttgccatc cttgaggaat
     4381 tgaattatac caagctaaaa gttctggact cttttcaact acctttaata aatcaggggt
     4441 aagaccctct attgcagtag gaactattgt caaaaggaat gtagctgtag ctaataaacc
     4501 tcctgtcaat ccatctaact tatatgactt tgccaaacta taacctatgc caaatgtaga
     4561 atatactgat ataataaaaa atgtcatcct atatggtagt aatattgtaa ctgcattttc
     4621 ctttatatac tgagttaccc cccatgaatc tggtaatgga ggaaatgcta atatcaagaa
     4681 aaatgaacca actattataa gtggtagtga agctacgatt ccatctctta cagctcttaa
     4741 gtgacgttgt tctgccaatc tagccataga tgttgataat ttaatgtcta aaaattctgt
     4801 aaatttatct agcatctttt ctctccttaa ttaatattta tttttattat cattaaaatt
     4861 tttgtaaaat taactttctt ctactctagc aacttctaaa actgctattc actcaacagc
     4921 tcttgaactt gttttaataa ctttggccct cctaatggac tataagcttg tgcttttatt
     4981 aatgcacatg gtacaccaac ttcatcagcg aaacctttta aatagtcaaa tctatgtctg
     5041 acttgtggag ctaccatagc aatatcccat ccatttttaa cttcatcctc aaactcttga
     5101 gtgccaacag ctaaaacatc tatatctatt ccattttttg ttccttcttt ttgtaatgca
     5161 ttaactgcta tagcacttga catacctgat gaacaaacaa ataacactct catatttatt
     5221 cccccttatt tttttatttc ttttcaatca ttatagcatg tatttttaat tacaggaata
     5281 cattttcacg ctttttttca ttatttacaa aattacttgt aattttattt caaatattta
     5341 tatcttattt taatctattt atatacctaa tcattctttt tactaaaatt acacacaact
     5401 tcaaatactt atatcttctt ttacaaaaaa aagcatggag actatctcat tattaccata
     5461 aaatagtctc catacttttt taaatatgta tacctttata tatccagaag taacctatta
     5521 ttgcaaatga caaagcaaat aaaatataca gtctaaaaaa tcctaaagaa aaacctctct
     5581 tagtttcaat aaagtacctt gtatatgcaa ctgcaaaaga tgtaattaat gaatttccta
     5641 taataactcc taatctatta tctattccaa atatagataa taaaacagga aaaattacag
     5701 tacttactag agatgacact attagtatta atccactttt aaaacttata gttggaatat
     5761 tataatctgt tttttgattt ttctccattt ctctcttagt atttttatta ctttttgtaa
     5821 tttttgcatt tttataatta ttatttttct tttttttatt attagacatg tcatttacct
     5881 ccaaaaggtt taggtgttat attccctaaa ataactttac ttttagcccc tgttgcagat
     5941 attacattag aaaaagaatt atttaatgtt tcattgccca agattacaaa tgccaaagcc
     6001 tcctttgcat cagaagaata cccatattca tcctgagtta atacttcaac ccctaataat
     6061 aactctttta tatatcttat taaagttaga ttatgagctc ctccacctcc aattaataaa
     6121 gtatctacat taacctttgg aagtatgaag tttttataat tataatatat agcttttgct
     6181 gtaaacatag ttactgttgc tatcaaatca tatttatcta catgtttata tttgttaagc
     6241 atgttatcta aatagacctg tccaaatatc tctcttccag tgctttttgg tggtgattga
     6301 ctaagatatt tatgactcat caaatctttt aacatttctt cattaatttt accttttgat
     6361 gcaaagtatc catttttatc atacctttta ttaaataatt tttgacatac tccatctatt
     6421 atcatatttc ctggacctgt atcaaatgca aagacatcct ctatgttaca tgatttaggt
     6481 attatagtaa tatttcctat tccaccaata ttttgaagtg ctacattttt attgttatca
     6541 ctatataata aaaattcact atatgggact aatggagcac cttctccacc tgctgctata
     6601 tccatcactc taaaattaga tattactttt gtatttgttt catgtgctat aactgctggt
     6661 tcacctattt gaagcgttga agatacaaaa ttattataac ttcttggtat atgaaagatt
     6721 gtttgaccat gagatgcgat aaaatccaaa ttttctatat taaagtttgc tttataacat
     6781 actgatttta cagctttact aaataaatat ccaagcttaa aatttaagct acaaattaaa
     6841 tcaacactcg attcctcttc tatacagcac tttcttattt cgtcttttat atctttagga
     6901 atttctagag ttataaattc tatttgctta attttggtat ttctaccact cccactaatt
     6961 tcagctagta ctgcatcaac tccgtctaag gaagttcctg acattaaacc tacactatac
     7021 atagttatca tccttttaag tttatagtta ttcctcccca atcaaagtat taagtttaat
     7081 aattttagaa ttaatattat tccatcttga attatgataa tttactctta cgaaattaat
     7141 tgagttaatc ttatatacgg tttttacctt agctaaatct tacctcaatt tattttcagt
     7201 gtcaatgtaa tctcatgtaa ttttttttca catacaaaac acattctatc tccaaaaaac
     7261 atattaaaat agttgctaca aataaaaaac ataccaggta tctatctggt atgtttttca
     7321 tatataataa ttattatttt ataagatgga tagagcatca tttaagtcac taattaaatc
     7381 ttcactattt tcaagaacta aacttattct tattctctat ggcgatatat tttatagcct
     7441 ttataataac ctaactatct aggtttaaat aatcagatat atcataaaaa taaatattaa
     7501 aaattgtata tgaaccattt tccgaacata cctcaatctc atgccctaaa ctatctatca
     7561 ttttctttac aaaatacagc cccattccag tagacttata caattgattt cttccatttt
     7621 tccccgtaaa tcccttgtca aaaactctag atatatcttc ttcatttata cctataccaa
     7681 aatcttttat agataatacc actccatttt ctaatttttt tgaattaaat tcaatcttac
     7741 caacttcctt tgaatacttt atagcattat taataatttg ttctaaaata tatgacatgc
     7801 atttagaatc tgtataaaca tcattttcta attcattcaa actaacttct acattatttt
     7861 ttataagcaa aaatgaatta ttttttatag acattctcac cattttatct aaattaaatt
     7921 tatttacaaa taaatcttca aacatagtgt tacttctact actatacaag atagagttta
     7981 ctaagaaatt tatctttgca atctgattct taatatccaa actatcttct atgttactta
     8041 acctatctgt aattatactt aaagaagata ttggaatttt tatttcatga acccatttag
     8101 ctatgtattc atctaattct tttaaagact gtttataact ctctatgtca ctattatttt
     8161 tcatttttaa attttctata atatctttta ttagattttc ttcaaaagat tgtccatcaa
     8221 ctaaataact gtctatttca ccactatctt ctatacaatt atataaattt atataactat
     8281 ttctaaaatt tatataatct ataacaaaaa ataccattat tataaacagc actaaaaaat
     8341 ctaagtatat taactctgaa tatctatttt taaaaatatc tatagcaaat aaatagatat
     8401 ttattatact aactacaact aaaggtagag caatatactt agacctacct tttaaatatt
     8461 ttactagcat tgtattatat atcctattcc cttcttagtt tttataaaat catcaaaacc
     8521 taattcttta actttacttc tcaatctatt catatttaca gtaagtgcat tgtctgtcac
     8581 aaactcatca ttatcccata gagtcatcat aagactttcc cttgatacaa ccctattctt
     8641 attttttaat aataatgtta aaatttttat ttcgttttta gtcaactcta tacttttatc
     8701 cttatactta tgttttataa tccctttccc cacatcaaac atcaaatctt cacaatacaa
     8761 aatactatta gaatcactat aattatagac tcttcttatt ataccattta ttttggtaac
     8821 caatatgtct atagaaaatg gtttggtaat ataatcatct gctccattat ttatacccat
     8881 tattaaatcc atatcagaat cccttgatga taaaaatatt aatggtacat ttgaaatagc
     8941 tcttattttt tcgcaccaat aaaatccatt atataatggt aaatttacat ctaaaagtac
     9001 tacatctggt tttttatcca caaattcatc taatactatc tcaaaatcat caattaattc
     9061 tactttaaat ccccatttct caagtgctaa cgcaatctct tttgataaat caatatcgtc
     9121 ctctactaat aaaattctat acatttgtat attctccatt atcctaatat ttcactatgc
     9181 cacgaattat taatatcata acatatttta tataaattta ttacccaaat catttagtta
     9241 atcaacaagg agactcttat tacaagaatc tcctttctct ttattaatat ataaactaat
     9301 ttttatacac tacactctta aacttattaa cagatactgc tccatatatt atgaatatta
     9361 tcaaacatat cactaaactt agtatatata taccaaataa gtcggtcatc aataaatctc
     9421 ctgctaatct caatgcaaaa taactagata tagttgcact taccattggc aaagtataaa
     9481 atatagctac ttctttaagt atagctctat ttatatcttt ttctgtagta cctattttta
     9541 ataaaatctt gtatttttct ttatcttcat atgcatcact atatattttc atatatatta
     9601 tacttccagc tacaattgca aagactaaga ataaaaacac aagcactaca tatgcaaact
     9661 tcatccattg actctcgcct tgagctttat atccattctg aatatatcca ttttttaaac
     9721 ttaagttctt ttcaatattg ttgaacatta ctttgctatt ttcttcttga aatacctttg
     9781 caccataaaa atatacttgt tgacccttat ctcttaattt gaaatatgta tcgtcattta
     9841 ctactatgat actttgatta agtcctgtcc ctagtactgg aacttttact tctccccttg
     9901 aaatattata taactgacca tcaagtttta tcttggcttc ttttgtagct attgatgcta
     9961 tcgtttgagg gctttttaac tctattacat tatttccact aactaatctt tcaccatact
    10021 cttttaattc tttatcattg ccattcactt taagagtatt acaaaaatca ctatatttca
    10081 ttatagtatc tgttgtatca taagcttctt ttatatctgt tttctttaaa attgttagtt
    10141 ctgggtttac tgaatacttt atcttattag tatcttttat tatattctct atttgttttt
    10201 tattcacttc atctttatcc attgaaacta tgctaatagt gtacacattt ctttgttctt
    10261 gggcattctt atgtatacga ttcatcgcaa ctgaagcacc aagagttgat attgttgtag
    10321 ttataattat agctattata gcataagttt tatagttttt atttaatcgg tagtttatat
    10381 tgtttattgc aattatatta tttccattaa ataatatttt tttatttttg attataatat
    10441 caaatataac aggcataact gatttgaata agccataagt acctactatt attataccta
    10501 taataggtag tacactagtt atatctccag ttcttatatt agtagaaaga tagtagccat
    10561 atcctattac tataattgat actatagcta atatatatat acctattcct acctttggta
    10621 ttttttcttg ttttttagat atattgatta gatttattac actacttcta catattgtta
    10681 taaaaccttt tacagccatt attataaata tagaaataaa tattaaagta gcatatagta
    10741 tagcttctat gctaagtcca ttagatacct ttatattaaa tccagataac tttattatca
    10801 ctacttgaaa aaatctagat gttattatcc ctataattat tcctgttata caagaactta
    10861 ttcctataag catattttct acaaaatata tttttcctat agtatataaa tctaatccca
    10921 taaaggacaa tattccaatt tctttagacc tattcttaaa aaatatattt gttgcatacc
    10981 atataaagaa aaataaaaat actgatagta tcattattac agctactaac actgatagtg
    11041 taaatttttt attttcctct tgtaacacat ttatagcatc accatatctc aataattcaa
    11101 aattagttag cacaactact gaaaaaacca tagatataaa aaatgctaga taagttctta
    11161 tgttactctt aaaattatta taagcaattc caagtatact cacttacatc tcacctccca
    11221 tagaggctag catatccata atctttccat aaaattcttt tctactattt cctttgttta
    11281 atttacactt tatatttcca tcatttatca tatatacttc atttgaatag cttgccgtta
    11341 gagggtcatg tgtaatcatt ataatagtag cgttgttttc tctgtttatt ttttctaatg
    11401 attctaaaag ttcatatgct gatttagagt ctaaggcacc tgttggttca tcagcaaata
    11461 tgactgctgg atttgtaatt aatgacctag ctgctgcgcc tctttgtttt tgtcctcctg
    11521 ataactgata tggatattta tctaaatgat tttctaatcc aaattttttg gctatagaaa
    11581 ataccttagc ttctatctcc ttacttttct tttttcctaa tgctagagga agtgctatat
    11641 tgtccattag tttcatattg tctaatagat tatagtcttg aaatataaac cctatttttt
    11701 ctcttcttag ttttgatagt tcattatttt ttacttttga tatattaatt ccatctagta
    11761 ttatttctcc tgaagtttgt ttgtcaagtg tagacattaa atttagtaat gttgtctttc
    11821 ctgcaccaga tggacccatt atcgctataa aatcaccttc attgactgta agagatatat
    11881 tttttaacac atttgtttta aatcctttta ttccataatc ttttgagata ttttttattt
    11941 ttaatatttc tttcataata atagcctcca gttgctaatt ttttaatata tctttatttt
    12001 aaaggtttta tataaataaa tccttaagta aatattacat tttaactgtt agcattacac
    12061 ttttgtaaca tatggaagac tattatagtt atagtggaaa tatcttaaaa taaaagcatg
    12121 attcactttt ttgtataaac aaagaaaaga agcccctaag aagcctctaa tctatacaat
    12181 aattcttctc tataaaaaac caaaaataca accttgattg tggtaaatac aggtactata
    12241 aacaattgat attaccacta tatattaaaa caattattcc ttaagataat tcagtaagac
    12301 tatcaagcca taagctaagc atccaaaaag acttaatacc attaatgtat aattataacc
    12361 aatattaacg ctcaaaaaac cagcaacagt tggaataatc agagatgacc cccccataaa
    12421 tatacttaaa gctattaatt ggctactact tctaagtttt ttaggagaaa cttcaaatat
    12481 taatcttttt gaagtaatta aaattaaagg agtagaaaac acttgaaaaa cacacagtat
    12541 aataatgata tttgaatcat ttgttaaagc aaataataga aactgaactg ttatcataat
    12601 agcacttaat tttaataagt ttaaactgtt atattttttt aataaataag aaccagctaa
    12661 atatgttggt atctctaata atgactgtaa agaccacttt aaagatattt gagaatttgt
    12721 agcatttaaa gctatcattt tatctattac agtacagtta tttgctacca ccattgaata
    12781 tagtaaaaat aaaatacata ctagtaagat atatttttta tcttttaata attcaataat
    12841 atctttactg gttacattta tttttttgtt aatcttttca atatcaggta gtaaaagtat
    12901 atttataata agtaatacta caattaaacc aatagctaca gataatccaa aatacgagaa
    12961 tctaagaatc aagtaagatg ccaccatact tccaatagcc catccaattg acccaaaagt
    13021 cttaataaat gacaaataat tattaatttt atctccacaa cctattatcc atgtatcata
    13081 taaactacag caagtattta ataatcctcc tgacaaagca acaagtaata agtatattat
    13141 aaaagttgca gattcagtag aaaacataat aactgatgca attccatata ctgatagact
    13201 aattaaaaca atttttttca ttgtttgata cttatcagct aatactccaa ataataattg
    13261 aaataatata ttggttattg catagcttga taatataatt cctctttcaa atgctgagta
    13321 acctaatttt gataaaaaag gtgtgaattt tgttgatgca aaggcaaaaa taatatatga
    13381 gagaaaataa aatatgataa atctaaattt aatcgcttta ttaatcataa tcaatcaaaa
    13441 ttgataactt taataccact atttccttcc tgatgtaagt ttgaaagatg atattttacc
    13501 gtattaggat tctctataat aactaaagga atatataaag tattttcaag taatttatta
    13561 tcaatttcta ctagattttc ccccatatta acttcttgac cttgtttaac ttttaattta
    13621 aagttttctt tttttgttgt tgcactatcc agtccaatat gaataagaat ttgaacatta
    13681 ttttgtaatt tgattcctat agcatggtta gtttgagcaa taaaacttat tactccttta
    13741 gcaggtgatt taagagcatt gtcctttgct atcatagcaa atccatcccc cattacctta
    13801 gttgaaaata ctttatctgg aatttcttca agattaatta tccttccatc aatataggaa
    13861 ttaattgtaa ttacttcttt ttttctttta aagaacacta taaacactcc tctacataat
    13921 tagctttatt ctgattatca ttataaataa cgatattaag catactgcaa ctgaggaaaa
    13981 aagagcctta tagctctttc cccattgtag ttctttaata ctgcttatga tttgtttaat
    14041 tccaacaaat ttataaacat atgtaaacat gataacaata gttagtgtgt aaatttggaa
    14101 tatctgccct aataagacta aatagaaagc aatcatgttt tcttttatat ctttattctt
    14161 ttttaaatta taaataacat atgcactata tactgcacta aaattagaga ctaaatttaa
    14221 acttgcatta acatcattat ttaaaagttc tgaaaatgaa atatttgtaa ataatgatgt
    14281 caattctaaa tacactatat ataaaacagg caatattaga aaacaaccca ttataactga
    14341 aagaaatata ttttcatctt ttaatactgc tgtgacattt tttattttat ttgttatcat
    14401 gtttttattc tccttattta aaagttggcc agaaatcctt attagccaca atcatttcat
    14461 ctaagatttc ttttgctact tttgcacttg gaacagtttt actcatagta aacgactgcc
    14521 ataatttttg ataacttttt tctatccacg cttctacagc taatttttca gaagcaactt
    14581 gttgttccat tagacctttt tggaaagttg gaattttacc tatagacata ggctcaacca
    14641 tatcttttcc aacaagacaa ggaatttcaa ccattgcatc atctgcaaaa ttttcaatag
    14701 ctccattatt aggaacaatc agtaaaaatc tttcctgagt attgaatgct aatgcacaag
    14761 ctaattcaac aataaattga gaatgttcac ttgcatcaaa ccatgtatct cttgctgtac
    14821 cattttttat aattctttca cattcttcga atgtatcctt ttctcttcta tccataattt
    14881 catttgctct tgtataattt ggattggcat gttcaacagt ttcatcagcc attaaataat
    14941 attttaaata agtattaggt aatgtagttg gttctatttc taacaaatcc tttgccgctc
    15001 tcatagtttc tagccaacta gattctttat gttgaccttg aggtgtaaat tcctcatatc
    15061 cttttttagc acaatattcc tgtaatttag gcattaaatc atttccttct ttgtccttaa
    15121 tacttgtcca ccatccaaaa tgattcaatc cataatatct aacatcaaaa tctttacgag
    15181 aatttaaacc taaaactcta gcaaatattt cctctagaca tactggcata tcacaaatat
    15241 taataattct tgaatttggt cttaatacac gacatgcttc tgcaactata gctgctggat
    15301 ttgagtaatt aagcatccaa gcatttggag aatatttttc catatagtca atcatttcta
    15361 tcactggacc tattgttctt aatccatagg caactccacc tgctccacaa gtttcttgac
    15421 caacaacccc atattttagt ggaatttttt catcttgttc acgtaaagca tataaaccaa
    15481 cacgaatttg tgccattaca aaatcaatat cagtaaatgc ttcttctgga tttgttgtat
    15541 aactaaattt aatttctgga tttttctctc taacaattat tgcacatgct tcagcaactt
    15601 ttctttgtct ctcatcatta ttatcatata atttaattga ttcaatagga aatttatcaa
    15661 cactttcaat taacattgtt acaattccag cagtataagt actacctcca ccagcgatta
    15721 gtatcctctg tctttttctt tccatctttc cttctccttt acaataaatt ttcaaattct
    15781 tctcttacac ttggtactga aagtccaata ataatctgaa tagcttttcc attatgcact
    15841 aaaccatgtg cacctactgc cttaaaatct tcttctttag aaatgattga gtcatctttc
    15901 aaggttaatc tcagccttgt agcacagttt gtaacatcta caacattttc tgctccacca
    15961 actaatttta tatattcagc tgcttgttga gatgctttac ttaatttatt tcctttttca
    16021 tctttagctt ctaaatactc atttttggta tatagttttg tttcttcagt atcttcctct
    16081 ctaccaggag ttttcatatc aaacttctta attaagaaag taaatacaaa gaaccagata
    16141 aacgaaaaga taatccctac aacaacttga ataatatata ccttccagtg atacattcca
    16201 agaggaagcc aatttaatac aacccagtta ataattcctc caccaaaatc accaacaact
    16261 cctaaggcaa acgaaatcgt ttgcaagcat gcatctaaaa atgcatgtac taggaataaa
    16321 agtggtgcta taaataaaaa tgtaaattct aacggctcag taattccagt taatactgca
    16381 gtaagagtag caggaatcat taaacctaac actttcttct ttttttctgg ctttgcagtt
    16441 acatagaaag cagcaaatac tcctaatgaa ccaaacacct tcgatagccc agataatgaa
    16501 aatccaattg gatacatttc ctttagagtc ttagctgaag tttgaaagtc ctgaatatga
    16561 gtagcccaat atactgatgt accacctgga acaacaacac tatcataaca aattggtgca
    16621 tatacaaaat gatgtaatcc agttggtatt aaaatctttt gtaagaacgc ataacaccaa
    16681 acgcctatat ttccactatt tataaaaaac gtttgcaaat gtctaataac attttgaaca
    16741 tgaggccaaa taaagcaagt taataatgca actggtatca taacaaagaa acaaattgca
    16801 actacaagtg atgaacctct aaataatcca ataaaatctg gtagttcttt atcataaaat
    16861 ctattatgaa cataaataac aatacctgat attaacaaag caccaaccat accagtatct
    16921 agtgttttaa taccagcaat gcttacaagt ccacttccag cacttatttc agctgcgaaa
    16981 tcaactccaa agctttttcc ccaaaaactt aacatagaac ctacaaaata attaaaagtc
    17041 aagtatgttg ctaaagcttc catacaagct cttgcttgtt gcttttttgc aagtgctatg
    17101 ggtaaagaaa tagcaaataa taatggtaat tgattgaata ccatccaagc tccactagat
    17161 ataacacccc aaaattggta ccaaatattt tctggtgtag caagtgaacc cataattgac
    17221 tgattttgaa atacaattga gaatccaacc attatcccag caaaagcaaa taatagtgtt
    17281 ggtgtaaaca ttgcccctcc aaaacgttgt attttcttca tcatataaag tactcccctc
    17341 ctcatatttt tattttatct ttggccttag atatctatta ttttaacatg ttaataaata
    17401 tatacaatct ttggactaca ttcggagctt attcacagtc aaataagttt ttgcacattt
    17461 ttatgttcaa attttcaaaa aaaaaagaat gactacaatt tgcaatcaat cccttctgta
    17521 atcattctat gccttttata aatactatat ttaataaata acaactcaat caatataaaa
    17581 tataacattg tcaatttata actagggtgc atttgtaaaa atgagatatt agtcgctgaa
    17641 atataaattg attcatcact taaatcagtc aatgtattat ttttaaactc tgtaattgaa
    17701 attattttag ttcctattaa ttttaatctt ctagcaatat taagtgtatt ctcattctca
    17761 ccacttaggg atataataat cataacatca tttttactga caatattgta aaaagaatca
    17821 tcaaatgttc ttccctcaaa atcatatatt atttcttgac atgataagaa cattctcttt
    17881 atctgttttg caaccacatt ttgaatatca cctgaaccat aagcgtatat tgttcttgat
    17941 tcataaagaa gtttacacaa tgcatcataa tctttatttt tttgatcttc aacatactta
    18001 attattgaat tgcatgcaat atcaaatgac tgattttcta taacatgaac cttttctgat
    18061 tcccagctta ataatacttt aaattcactg aaacctttta aatctaattt tttaacaaat
    18121 cttgtaatag ttgcacgaga cacattacat ttcatagcaa gttcatttat tgacatctta
    18181 ctacaatgtt ttttatttgc agttatatat ttccatatta ataaatctgt ctcattcagt
    18241 ttattataat ttaaaaaaat catttcttct aatctcataa actattatcc cctttaatta
    18301 aaaattgtca taactattat accaatattc aacattaaat tacagcatat tcttatattt
    18361 actatttagc ctataaaatt gactataaaa aatacagcta taattgatgt taaaaaaagt
    18421 agttttaatt ctattctttt atctaataat taatattttc aaattctagt gcttttctta
    18481 tgcaattatc ctctttaaaa tcagcagtcc ttttacaatc ttttacttta aattctggag
    18541 tagttttaaa ttcctcatca catactccac tcttatttaa atacatacaa cttgccattc
    18601 taactattag accactattt tttaaattaa acaatacagg gtctatacac cctccatctc
    18661 caccagtagt ttcaccaact aaagttgcaa atttagtttc tttacaaaac attgcaaatg
    18721 actctgatga tgaatatatt tttctatcaa caagtaagta tatattaccc ttaaatttta
    18781 aatcatctgt agattttata gtataggaag tatcttcaaa accattaaaa tcttttataa
    18841 tttctttagg tgcattttcc tttacacttg ctggtaaact ttctacagga tttaatttta
    18901 tatttcttgc agttgtatat ttttttacta tttcattatt atttctataa attctataac
    18961 catttatttt gacatcattt tttatgagtt tagatacgat tccttgccaa tacctatcac
    19021 ttccacctaa attacctctt atatcaataa ttaaagcttt atgttttttt aaagtgctaa
    19081 tataatctcc aattattttt aaatcattat ttatagaccc attctttgat gacattgatg
    19141 gtaagtacat atatccaatc ttacctttaa taacatcctt taaaatcaat tcttttttta
    19201 caaaaatatc atctggcatt tttattttag gattcataga gtcatatcta tctacaactt
    19261 ctttatcatt aagaaaatca taccaatcat tattagagta tgatttctta aaaagttcat
    19321 atcttttctt gttatctatt acttctgtgt gcttattatt taaatcagat aatatagatg
    19381 acagttcttc tataaattct tcgtcatttt cagtacttct tattcttttt atatattcat
    19441 ccttattttc taaccaatca atattattaa gcctcttatt tacacctaga tatggatatc
    19501 ctgtttttac aacattatac acataattaa agtcatctac cttttcttct tcagacaact
    19561 gattcttttg agaataagta gaattaccta ataagattat aaatgctaaa ataattacta
    19621 aaaataatac tttctttttc atgtaattct catccacttt cagattttat attttaatac
    19681 attgtatcat tattttatta tcacctaaac aactaaaaga aattcttgaa gatatattcc
    19741 actattattc tctttaaaat atttttattt atatttttaa aattatttca tgaaaattat
    19801 aaaataacaa tcatattcaa atatctgttt tacttccata tcctgaaagt aaattcttat
    19861 cagtgatata ctaaaaaaga tgtgctaaaa aatttatcca ttataagggc ttaaatttag
    19921 atactttact gatttttatt tattagttga gaaagatatt gataattaaa aatattgata
    19981 actatagaaa tgattatttt ttatataaat ttaaggatat aaactaatta tacttaagtc
    20041 tatatcctta atttatcatg attacgaaaa tttttacaaa cacttatatt tgtctgtttt
    20101 agaataaaaa caaggacata tcctgttatt ttattcaaac atccaagttt aattactaca
    20161 caattacttg ttagaaattg tatctacttc atatatatat ctgttaagta tagcttctag
    20221 catttcttgt cttccagact tattctttat aactggcatt tgcagtgcat aagattctaa
    20281 ctctttaaat ccaaccttac cttctactat atctttacct ataccctcac taaaacttgc
    20341 atatctttct ttagtaaagt tttcaaatac ctcatcttct aataatttat gagctattaa
    20401 caatcccttt gcaaatgtat ccattcctgc aatataagct aggaataagt cttctacctc
    20461 aaaagatgct cttcttactt tagagtcaaa attaaatcct cctggtgcta ttccaccttg
    20521 ctttaagact tcatacatag caagtgttgc atcatatata tttgttggaa attggtctgt
    20581 atcccaacct aataataggt ctccttgatt tgcatctata ctacctaaaa cattgtttat
    20641 tctcgctata tttaattcat gttggaaagt atgccctgca agtgttgcat gatttgcttc
    20701 tatattcact ttgaagtatt tatccagatt atactttctt aaaaatccta aaacagtagc
    20761 agtatcaaaa tcatattgat gtttagtagg ctcttttggc ttaggctcta ttaagaattg
    20821 tccagtaaat cctatttcct tagcataatc tacagccatt tgtaagaatc ttgcaaagtt
    20881 atccatttca agttctgtat tagtgttaag taaagtttca taaccttctc ttccacccca
    20941 gaatacaaaa ttttctcctc ctaagtactt agttatttcc atagcttttt taacctgagc
    21001 tgctgcatat gcatatacat ctgcattaca tgttgtagat gcaccatgaa caaatcttgg
    21061 atttccaaac atattggcag ttccccataa taactttata cctgtctttt ccatattagc
    21121 ttttatatac tcaactattt catctagtat cttatttgtc tcttctaaat ctcttccttc
    21181 tggagctata tctctgtcat gaaaacagaa atactcaatt cccatcttag acataaattc
    21241 aaatcctgca tcaactttaa tctttgctat ctcaattggg tctgttatat tattccaagg
    21301 tctctctact gtacctactc caaatgggtc attaccctct ccacataaag tatgccaata
    21361 gctcattgca aatcttaagt gttctttcat agtcttattc cctactactt gttcaggatt
    21421 gtagtatcta aatgctaact cattgttaga ttttactcct tcaaatttta tctgtcctat
    21481 tcctttaaat atttcattca tttcatgtcc tcctaatatt ttacacatat aatatatgta
    21541 gtatgttttc ttaatttaaa actattttct atctttattt tctttttatt ttaagctatc
    21601 ttgtctattt atttttgcaa ttaactgctt catctaacaa cctaaagtcg tctttcaaag
    21661 atttgtatat ttttttatac aatctgtgat atgtcttgta tatatctaca ttttcactta
    21721 ttggttctaa tttagttgaa gtttttatta tagtatcaca agctttttgt atattttcat
    21781 atattccagc tcctactaat gcaagaattg caactccaag tgctggtcct tcacttgaat
    21841 ttatagtata tacatcttga ttaaacatat ctgcttgcat ctgtctccat actttacttt
    21901 ttccacctcc acctgaggct cttacttcat taacgtctat attaagattt tctattatat
    21961 ccatacagtc tttaagacta tacgaaacac cttccattat tgaccttgcg atttcttttt
    22021 tagaatggat tggagacaat ccaaagaaca cgcctcttgc ataagggtca agatgaggag
    22081 ttctttctcc catcatatat ggtaagtaaa gcaatccatt acatcctgtt ggtacttgac
    22141 ttacttgatt atttataata tcatacacat cttcgtctaa agaatttgaa acttccactt
    22201 cactttgaca gaaattatct ttaaaccatt ttaatgacaa tccagctcct tgagtaactc
    22261 ccataacatg ccatgtattt ggtattgcat gacagaaagt atgaactcta ccttctttat
    22321 caatttttgg ctcttttgta taagcaaata ctacacctga tgtacctata gtggacgaaa
    22381 ctactccatc tttaactatt ccatttccta tagctcctgc tgcttggtct ccagctcctc
    22441 ctaccactat tgttccttct ttaagccctg tcaaacttgc tacatcttta gtcacataac
    22501 ctgtaacctc ttgtgattca taaactttac ctaaaagatt tttatctata tttaactttt
    22561 ctagtacttc atcgctccaa tctctttttc ttatatcgag caactgcata ccacttgcat
    22621 ctgatacttc tgtagcatat tcacctgtca atttgtatct tatataatct tttggaagaa
    22681 gtattttatt agtattttta tatatatctg gttcattgtt tctaacccat aatatctttg
    22741 atgctgtaaa tcctgtaagt gctggattag cagttatttc aatcagtctt tcttcaccta
    22801 ctaaatcagt tatctcctca cactctttta ctgttcgttg gtcacaccat attatagatt
    22861 ttctcaatgt tttgccttca ctgtccagca taactagacc atgcatctgt cctgataatc
    22921 caattccttt tatacattca ctacttatat ttgaactttg aactacttct cttatagatt
    22981 cgactacagc tttccaccaa tcatttgcat cctgttccgc ccaacctgat ttttcttgta
    23041 taagaggata ttcatacgta caacttttta tagtatttcc tagtttatca aataaaactg
    23101 ttttagtacc tgatgtacca atatccacac ctaatacata ctccaacttc atccctcctt
    23161 gaatgccact tcataattat cgttttccta tcctaatttt tttatatttt aggtatattt
    23221 tacttgcttt atttttgtta gtatattaaa ctaacttatg aactaataat aaaatattta
    23281 attatctttg tcaatgcaaa ataacctttt atttttgtgt aaaaagtatt acaatattat
    23341 tttaaggagg aatatcaaat tggttactga taaatacact attcgagaaa tgaacgaaag
    23401 attagtactt gaacaaatta taaaaaatgg tcctatttct agggcaagta tagcttctac
    23461 tataggattg aataaagcaa ctatatctgc tattaccaaa aaacttattg atgaatctct
    23521 agttcatgaa ataggaattg gaaatagtac tcatagtggc ggaagaaaac ccatattatt
    23581 agtatttaat aaatgtgcag ggatttcttt aagtatggat attggatacg actatatatt
    23641 ttcttctatg tcttacttag atggaactat tataaattct aagaaattaa cagatataca
    23701 agtaagtaaa gacaatgtta tacaattgat agatgaaatt ataaatagtt ataacatatc
    23761 caaaatagac actccttata aggtaatcgg tctcactttg gctatacatg ggattacttg
    23821 tgaaaataaa gtattattta ctccatatta caatcttaat gagattgact tatatagcat
    23881 ccttagcaaa aaatatgact ttcctattca tatagaaaat gaagcaaact taacagcttt
    23941 agccgagaat actttttcaa ctgtacatga ctcactactc agtctcagta ttcacagtgg
    24001 atttggttca ggaattataa taaataataa attatatagt ggcagaaatg gtatgagtgg
    24061 agaaattggt catactatca tcatgcctaa tggtaaacta tgtccttgtg gaaaccgtgg
    24121 ctgtttagaa cagtattgtt cagaaaaaaa ggtatttgaa cagctttctt ctttagaaaa
    24181 tattcctaag atagattctg atatagtaaa gaaactatat tatgaggata accagaatac
    24241 caaaaaagtt atccatgaat tttgtagcta cttaacaata gctataaata atgctattac
    24301 aacctatgct cctgagataa tatatttaaa tagccaaata attagtgata tccctgagat
    24361 attacagatt acaaaagata tgttagttag ctcttttaac aaaggaataa atatagaaat
    24421 ttcatcatta gggtctgagg catctctata tggtggctct gctgtaaata tcaagagctt
    24481 tttgaatata caaaatttaa ctttaattaa tgaaatataa gggttatgac tatatacagc
    24541 cataaccctt taaattatac attctaaaat taaatttatt acatagatta cgcaagatta
    24601 gctatatctt ttaaaaattg tatatcaatt aagcattaac ataagtattt tgttttaaat
    24661 attaatataa tcttcctact catcatcaga taataaactt gtattttgtt caaccataga
    24721 aatattatct ttacctattt tctctaattt tactaccaat tcatttgtat ctaaaaaagc
    24781 tgattcaata accataccta aatttagccc tgaaataatt ttaattcgac tatcattatt
    24841 ggctactaat aaagcagcat tgcatggagt tccacctagt aaatctgcca ttataattat
    24901 ttctgaactt tccttgtaca cttctaaagc tttttttaat ttttctattg ttccttctat
    24961 tccatcatct tgtttcatat ttacagtagg ataatctata gaatccccta ttatcatttt
    25021 tgcagaattt aatacttctt cagccatatt accatgactc atcaaaataa tactattcac
    25081 tttaatacac ctctttaaat ctataagatg tctacaagat aagttttctt atcatcaggc
    25141 gtcattatag ttgtaatctc aattccttca tctaaaagtc ttttaaatgc ttctttctct
    25201 tcttcagtaa cactgatatt aggttttagc actgttgtat cttttctact tgacatatta
    25261 cctacattta tattatgcat tttaaatcct gcctctacaa atggaataag gtccacagga
    25321 gacttaacaa ttagtaatac attttgccct tcatactttc ctgcagtaat attttttata
    25381 gcagtctctt ctgtaattat agatgacgct atacctgcag gtgtagccat tcttaaaact
    25441 tgtttttgaa cagaattgtt agctactgca tcatttacta ccattaatct tgtaacacct
    25501 aatttattac tccacatagt tgcaacttga ccatggatta aacggtcatc tatacgaata
    25561 tttttaatac ctttcatttc catatctaat accatccttt ccttatttta aaatacctaa
    25621 tgcatataaa attattgaaa caaccattac tcctaaaatt aagtatatag gttttatatt
    25681 ctttttaaga gcccaataaa caatcacaac taaaattgca ggaactaacc caggcataat
    25741 ttggtctaat atttcttgac ctttcattgt aaaatcacct tgttgaaagt tcaaagcaac
    25801 attagctttt actactgaag gtattaaggc acctacaacc attaatccta aaatagatgt
    25861 gctctcagtt aaaatcttta aacttttttc aattgaagat attagcttag tacctgatgt
    25921 ataaccagca ttaaatagcg gtatacttaa taatttcaat gctacactca ctataatcca
    25981 cagtaagatt ccaaatggac ttccatctat cgccatatta gctgctatag ctccaaaaat
    26041 tgtccacgga ataacaacaa ataaactatc tcctaaacct gctactggtc ccatcaagcc
    26101 tgttttaatt gaagcaacag cttcttcagt ctcttcactt gataattcct ccattgctac
    26161 attaataccc aaaatataag gtgccaccca aggattagta ttaaaaaact gtaaatgatt
    26221 taatacagcg ctttgtaatt tttctggatt atctttgtat actactttta aaaaaggtag
    26281 tactgcataa cagtatgcca aggcctgcat cttctcataa tttgaagaaa cagaactagt
    26341 aaaaaaccag cgccataaga cacttttttt cactttttca tttgatttat ttaatgatac
    26401 cttatcactc atcttcgtcc atacctccta ctacagtata ttgttgtgct tgattttcca
    26461 aattcttttt gtaaattata agtgcaattg ctccaccaat taaagctaca cctaataatg
    26521 gtactttcat atatactgct aaaacaaaac caattactaa ataactaaaa tactccttag
    26581 caggaagata tctaagtaat aatcctatcc ctactgctgg aagtagtcct ccagctactg
    26641 ttaaaccacc tgttaaccat tcaggcgtat attttaaaat tgtattaatt aaagaaggtc
    26701 caaatattac agatagagca actggaatac ctgttgtagc tgctgttaat aacactccta
    26761 acatctgcat atatgttata tttttataat ttcctttttt agctccatct tctgctttat
    26821 gcactaacca tataccgata gtatttctaa gaacatctaa ttgtaccatc aataaagcaa
    26881 ctggaatacc tatagaaatt cctacagatg cttcttgctt agttgtaata gttataaatg
    26941 tggctactat actggctgtc tgataatcag gtattgatgc tccaccaaaa ttactaatac
    27001 ctaatgataa tagttgtaat gtacctccaa tatataaccc tgtatttata tctcctaaga
    27061 taagaccagt aataaaacct gctgttactg gttgatatgt tccaaacatt gttgaatttt
    27121 tttcatagtt tataaaaaat ccatatagta cgattaataa taattgccat aattgtggct
    27181 ccattatgat ttcacctcac tcaaaatatt ttttaattct ttaaagttat aactagaatc
    27241 ttgctttaag aaaataggaa tctcttccag tgggcattca atttcataag ttttcccacc
    27301 ttcataacta actccactaa atatattttc ccatgtatgt ccttttggta aatatacttt
    27361 tctacttcta tctttataat tcattattgg agctaccaaa atttcatctc caagcatata
    27421 tgtattatcc acctcccaag ttttatcatc ttcaggaaat tcataaaata gagttctcat
    27481 aactggtgtt ccatcttcat gtgcttcttt catcagtttt tttaaataag tttttaaact
    27541 ctctctaatt tttataaatt tcgtaagaat tacttcaact tcttcaccat aagaccatat
    27601 ttcattagga gctccagtta ccattgagcc tccaccttta tttgacaatg gtttactatg
    27661 aggcaatcta tctccatgca ttctcaaaat tggtgaaaaa gtagcatatt ggaaccatct
    27721 taccataagt tctctaaact ctgggtcttt aggatttcct ccatggaaac ctccaatatc
    27781 agtagtccac catggtatac ctgccagtcc catatttaac cctgtattta cttgattatt
    27841 gaaagcctca aaactagagt caatgtcacc agaccatact aaagctccat acttttgagc
    27901 tcctgcccaa gctcctctca caagagttac aacagactct atgtcattat gtaagccatc
    27961 ataaatcatt tttaaataat caataggata aatattacca caacttaaaa cattaccttt
    28021 tttatatcta tagttatcaa aatcatacac agaatagcca ggttcagcta catctaacca
    28081 ataataatca attccaagtt gtttataatt tttatctatt ctatcccaaa catattctct
    28141 tgcattttca tttgtcatat ctacaaagac tgtatttcct tgaatttgca ttgtcattct
    28201 aacaccacga ttaacattga ctaaataacc attttctaaa taatcattgt agttttctgc
    28261 atcactttga actgtaggcc atacagatac tattggctct actgaatact cttctttcaa
    28321 ttttttaact aactctttag gatttttcca ataatctaaa tcaaatttat attcaccttg
    28381 cttaggccaa tgaaaatagt caattgcaat tgatgaaagc ttaattcctc ttttagaata
    28441 ttccttcaca acatctaaaa cttcttctga agttctatat cttagtttac tttgccatag
    28501 tcctaaaagg ttttcaggca tcataggaac agttcctgta acttgagaat agtttttatt
    28561 caactctttt gggctttctc cacaagtaat ccaataatct ataaattttg tagaaaacat
    28621 cttccattct gtcatatttt tagcaaaaga tactttccca atacccggat tgttccataa
    28681 aagtccataa cctagactag aaatataaaa aggaactgat atttgagaat ttctttgggc
    28741 taactccaaa acagtattct ttaaatctaa aaatttatgt tgatattgtc ccattccaaa
    28801 aatcttttca gaaggctcag attcaaatct agtagttact tcaaattctc cactatagct
    28861 tggtcgatat tctcttgatt ttaactttag agtagagtta aaatctttgg taatttcaat
    28921 tgtccctaca tcttctccac catcatcatg ttttacagct cttaatcgaa tatattcttt
    28981 caataatatt tcatttttat cattgtaaaa agtaattcta tctctatggt ctaagacagc
    29041 ttttatcttt ccatttttaa tgattgcact tccatcttca tttttattaa ttgtaatatc
    29101 atctttattt aacttaggtt tttcgttaag agcatagttt tcatcaacaa agttttggtc
    29161 tacaaacgac ctgatacgta aagagttttt tccccatgct tctattcgca atagttcatt
    29221 gtcaaatctt ttttcaatat agtcttcaga tatttttatc acggctacct cctaaatcaa
    29281 tggtataata ttctatcttt gtgtagctta agttaaataa tgtcatttag tttcgttatt
    29341 tataaattag attttatata attcatttgt acattaaact aacttaccaa taatatactt
    29401 tatttgactt tgtttgtcaa tcgctttccg gattttagta aaattttcta atatattgat
    29461 ggaaagtcat ccttaatatt ttttatttat actttttaat atctgtgatg atacctatat
    29521 acatctagat ttttaaaaca catacaggaa taatgtttac ctcttatgta aacaatactg
    29581 gacttaaaaa tatgtatagc gaccttataa atacagatga taatatatta gatattattc
    29641 aaaacaaagg attttataat tataaataat ttatgaaatt atttaagaaa atatataatt
    29701 gtacaccaag tcaaaaacgg caataaataa ataaaactaa aaaatacgtt gtctcaaaat
    29761 atagataaat ttatttttca tttctgaaat gattaaaata tatttgattt aatataaaaa
    29821 agagtgtctc atgaactaaa aagttcactt ttagacactc ctttatatat tatttacttc
    29881 ttaattcatt tattacctct ctacattttc tttcagctag tgaatacatc tgtactaaca
    29941 tagctactgt aagtactatt ggtataatac catttataga acgaatacca cacaaagctt
    30001 gtgaagtttg agaaatattt gcaacatatc ctgtcataga tagtaccaaa taccaatatg
    30061 aatattaatg ataatattga tttttttaaa tttttcttta ggagtactaa ttcctccact
    30121 taaaaatgct tcatgtactg tccatcagtc atatttttct accaaatatg atgttgtttc
    30181 ataatgagac aataaatatt tatacattta cttaccttct ctaatctcat caaatccaac
    30241 tataggtatc tctaaattat actctttaag tagcttttct agctcttcta taaaaatacc
    30301 tttcccttcc accatttgta tatcatttat tttatccatc aattcactac aaccacttaa
    30361 ctcaccaaac caacgtttag aactacatgt cttattatat ccacaacttg ggctaccatc
    30421 tattgcaata atacttttta tatcataatt attttttaaa tattcaccaa attgtcttac
    30481 ataaggtatt aacatttgcc tacattgttc tctaaaaaac aaattgtcaa actgttcttt
    30541 tacatgtccc cacctattta ttccatacat aatcatttct ggacatggta gttgaattat
    30601 tccataccct ttatttatta aatctattgc tatattttgt gctcctttaa attctgacaa
    30661 cccctctact ttagaattac aatttaatat acagtgacat actactacaa tctctctatt
    30721 tctcttcata ataatctcct tagttattct taattttaat gatactacat attttgataa
    30781 ttatattatt tatttgttct atatttccaa tattctatat agaaatatac aattagtaat
    30841 cttttataat ctatactatg ataaatgtat atattttttt aggaggtatt ataattggat
    30901 actaaaaaag tcacattttc ttcaatgtgt atagttatta atattgtctt aggtatggtt
    30961 atatctatga taaatatacc attattattt ttagatacag ttggtactgt acttggggct
    31021 gtcgtattag gtcctttttg gggtgctctt attggtgggt gtacaaactt agttttaggt
    31081 gttatatcag gacctacaaa tatacctttt gctcttgtaa atattgttct tggtcttatt
    31141 gttggatata tttctaataa aaaaggtttt ggttataaag aagctattat tacaggcgta
    31201 attttatcta ttgtttgtcc tttaattggt actcctattt cagttttatt gtttggtggt
    31261 ttaagtggaa gtggtgctga tttattggtt ggttttttag ttcagtctgg tcagaagata
    31321 tttactgctg cgttctttcc aaggattctt agtaatatag tggacaagcc tttgtcttgt
    31381 attatggtgg tatattttat aagtaaaatg cctaaaggtt ttataaaaca atatagtaaa
    31441 aatacgtata gtcattctta gtaaactgta tatattatat gatttgctaa aggttataat
    31501 gagtttatac acatttattt gtataatata ttttgcactt tattattcat taattttagt
    31561 attggtgatt taattatgtg ttatctttat taattt
//
LOCUS       DBGJFK010000041        31151 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.041, whole genome shotgun sequence.
ACCESSION   DBGJFK010000041 DBGJFK010000000
VERSION     DBGJFK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31151
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.041"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            203..409
                     /locus_tag="ACOIAP_002211"
     CDS             203..409
                     /locus_tag="ACOIAP_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639094.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGVEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(715..1458)
                     /locus_tag="ACOIAP_002212"
     CDS             complement(715..1458)
                     /locus_tag="ACOIAP_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HGZ2639095.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIKNIPRIINNIIILRGCEANILDTKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNHPKKLINHFHQKGKLLDVDYRNI"
     gene            1624..4191
                     /locus_tag="ACOIAP_002213"
     CDS             1624..4191
                     /locus_tag="ACOIAP_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2639096.1"
                     /translation="MTQRKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFSNINSINEYS
                     EDDSIKDEYILEGIKKENNIFNLVGCDGSLKSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLNIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGILFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESIRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKSFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDEDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYVLQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANEIDKGKGILILTDMGSILTFAKVIHDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEITYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRSKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            4421..4825
                     /locus_tag="ACOIAP_002214"
     CDS             4421..4825
                     /locus_tag="ACOIAP_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2639097.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            4849..5346
                     /locus_tag="ACOIAP_002215"
     CDS             4849..5346
                     /locus_tag="ACOIAP_002215"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639098.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEIELNHNINRY
                     KGEFI"
     gene            5349..5750
                     /locus_tag="ACOIAP_002216"
     CDS             5349..5750
                     /locus_tag="ACOIAP_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HGZ2639099.1"
                     /translation="MNKYKVIILCHGTWGKLLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKGVEEAVDKEDVKIIISDLYGGSTSSVAISVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            5768..6256
                     /locus_tag="ACOIAP_002217"
     CDS             5768..6256
                     /locus_tag="ACOIAP_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGZ2639100.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGSEDIKQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            6283..7038
                     /locus_tag="ACOIAP_002218"
     CDS             6283..7038
                     /locus_tag="ACOIAP_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGZ2639101.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLNVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            7038..7901
                     /locus_tag="ACOIAP_002219"
     CDS             7038..7901
                     /locus_tag="ACOIAP_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGZ2639102.1"
                     /translation="MQEIKNKDVKNGQGTTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKKKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIIFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLSVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            7948..8427
                     /locus_tag="ACOIAP_002220"
     CDS             7948..8427
                     /locus_tag="ACOIAP_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HGZ2639103.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGVNPDDIC
                     KEAIYGFGKMRGQKYSVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQSVRLEFAQKRAHDDEVCELVFTRK"
     gene            8492..9799
                     /locus_tag="ACOIAP_002221"
     CDS             8492..9799
                     /locus_tag="ACOIAP_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2639104.1"
                     /translation="MDISRRVDNSLNRTIEFLKELIKIDSQQGEPILQCPFGIGPKKS
                     LEKTLDYCASLGFSVKNIDNYIGYAEIGEGKELIGIPMHLDVVPPGDGWSVDPFSGVV
                     IDNIIYGRGAVDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMECIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIILRGGTKENVVPSHC
                     TAKIVNGIILELTTKGVAVHASNPEKGENAISKMVIKILKDNMNFQHREDIELVSKYL
                     CSDYYGNALGINRYDGVFKNTTLNLGILKVNEEKIVCELDIRYGKNIILNNIIDRFKK
                     FFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            10116..10238
                     /locus_tag="ACOIAP_002222"
     CDS             10116..10238
                     /locus_tag="ACOIAP_002222"
                     /inference="COORDINATES: protein motif:HMM:NF021468.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HGZ2639105.1"
                     /translation="MLSNKIIKKCCKIGYMIREKSIDIYSDSGWEFMVWDENGE"
     gene            10742..11836
                     /locus_tag="ACOIAP_002223"
     CDS             10742..11836
                     /locus_tag="ACOIAP_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2639106.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     LDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTAKPFDEVMIEIREI
                     IKRYYSCFPLIFRMGLLIVNHYDIVDEKKRELLIDEALEIFIRIQETCNDIDICRQAK
                     NMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQIDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISNIFELDTLSPATMLSAYLTQTQINLIH
                     EDNEGAIKSLRKYVDLATSDIYPITIHGDDFFDKLDRWISEIGIGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            11841..12041
                     /locus_tag="ACOIAP_002224"
     CDS             11841..12041
                     /locus_tag="ACOIAP_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLD nuclease N-terminal domain-containing
                     protein"
                     /protein_id="HGZ2639107.1"
                     /translation="MENLMEYLPLLIPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISIIGPILYFTIGRGEE"
     gene            12038..12958
                     /locus_tag="ACOIAP_002225"
     CDS             12038..12958
                     /locus_tag="ACOIAP_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2639108.1"
                     /translation="MMNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKT
                     TTMKMVLGLLEPDSGTIDVCGEKVTYGGTSSNRHVGYLPDVPEFYNYMRPLEYLSLCG
                     EITGLSKQEIKIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDE
                     PTSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLS
                     EIKSMHGKDRLLLEFASNDEIQKFKSSGDIKSLLKYSEETNMEIVLHGKDIKAIQKTV
                     ISTLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            12955..13713
                     /locus_tag="ACOIAP_002226"
     CDS             12955..13713
                     /locus_tag="ACOIAP_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGZ2639109.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLVFGIMSPLSAKFMPD
                     LIAHFAPTLKVTTAPTALDSWTQFSGNISGLGASLTLIVFCNILSNEYSKGTLVIMLT
                     KGLSRSSVILSKFSIAVIIMTIGFWLSFLCTYGYTMYFWPTENLNHIIFSAFNLWLIN
                     IMYITILILGCVLFRPAFASVLLVLVATLILSLISIPKQIAPYTPNFILSKNIDLVSG
                     KVAAPEFIIPMIVTIVISIICLLLAVILFKKKAV"
     gene            14189..15262
                     /locus_tag="ACOIAP_002227"
     CDS             14189..15262
                     /locus_tag="ACOIAP_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HGZ2639110.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDKAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKECEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCIGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKIGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            15332..15595
                     /locus_tag="ACOIAP_002228"
     CDS             15332..15595
                     /locus_tag="ACOIAP_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639111.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            15801..16778
                     /gene="bioB"
                     /locus_tag="ACOIAP_002229"
     CDS             15801..16778
                     /gene="bioB"
                     /locus_tag="ACOIAP_002229"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HGZ2639112.1"
                     /translation="MEKYIIKLKNKVLGGKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREFFMGRKADLCTIINAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNDILKIYERLRENTNLKLCASLGIIDYEQAKMLK
                     SVGVTTYHHNVETARDNFHNICTTHTYKDRIKTIKEAKEAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMEDYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDEVGFNGGVNSAIVGDYLTTVGNGIENDKKMIIEQGFEI"
     gene            16997..18019
                     /locus_tag="ACOIAP_002230"
     CDS             16997..18019
                     /locus_tag="ACOIAP_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGZ2639113.1"
                     /translation="MNFLSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKI
                     MKEKNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANKEGYNIILCNT
                     DEDAKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETL
                     KGIVKINNFEGAYIATKYLLDTGNKKIIYLSGPLQNEIAIDRLEGYKKALIECNLSYN
                     TDYVFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVV
                     GFDDIQTSSLISPSLTTVRQPSYDIGYKASEILINCLKGDKKESFDELIFKPELVIRD
                     STKESE"
     gene            18061..18954
                     /gene="rbsK"
                     /locus_tag="ACOIAP_002231"
     CDS             18061..18954
                     /gene="rbsK"
                     /locus_tag="ACOIAP_002231"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HGZ2639114.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCVGEDSLGEELIRNFRTNKVDYSLVSRNKHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRINVL
                     LNPAPAIKLDEDIIEKVTYLTPNEHEYKIVFDTNEEIEEVLKKYPNKLVITEGKNGAR
                     FYDGNEVKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEEVEKYLNNNK"
     gene            19002..19964
                     /locus_tag="ACOIAP_002232"
     CDS             19002..19964
                     /locus_tag="ACOIAP_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGZ2639115.1"
                     /translation="MKVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGASDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            20017..21528
                     /locus_tag="ACOIAP_002233"
     CDS             20017..21528
                     /locus_tag="ACOIAP_002233"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639116.1"
                     /translation="MSNIILKLSNIAKEFPGVKALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFQDKEIENISPDVSKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDVNPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLIKDLKDSGVSIIYISHRMEELFEICDRITIMRDGK
                     TVSTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDVSFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALRIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGNLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            21512..22510
                     /locus_tag="ACOIAP_002234"
     CDS             21512..22510
                     /locus_tag="ACOIAP_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639117.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSAFRDQGSAAVGLVIIFIIMSIAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWLGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYVGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKLAKSK"
     gene            22694..23956
                     /locus_tag="ACOIAP_002235"
     CDS             22694..23956
                     /locus_tag="ACOIAP_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2639118.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGIADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEHNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGINAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNVHKILEETLGRSLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            23976..24719
                     /locus_tag="ACOIAP_002236"
     CDS             23976..24719
                     /locus_tag="ACOIAP_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HGZ2639119.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDYNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     VDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            24892..26277
                     /locus_tag="ACOIAP_002237"
     CDS             24892..26277
                     /locus_tag="ACOIAP_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2639120.1"
                     /translation="MSDLNKKFLIEYIDEIQEELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKHDFSIDELEGMDTAFVASYGEGEPVIAVLGEYDALDGLSQKVSITKEPILDS
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDSCRVHYVTTNGGKMPNIVPDFAEVWYYIRGIKMEHVRDVFDRIVDIA
                     KGASLMTGTSMEYDIISGVYDYIPNTILTDILSQNMKLIGVQNYNEDDYHFAEKLAET
                     VSIDKRISVSSVLSGNKDITKMNLHGEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSIACSINDVMLDEVIINKAKKELKN
                     TIGSFEYIPII"
     gene            26489..27328
                     /locus_tag="ACOIAP_002238"
     CDS             26489..27328
                     /locus_tag="ACOIAP_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5685 family protein"
                     /protein_id="HGZ2639121.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDRRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFAYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYMNILESRGGK
                     NVQ"
     gene            27318..27761
                     /locus_tag="ACOIAP_002239"
     CDS             27318..27761
                     /locus_tag="ACOIAP_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGZ2639122.1"
                     /translation="MYSNTYNNEHFMRARAFIENNEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            27772..28263
                     /locus_tag="ACOIAP_002240"
     CDS             27772..28263
                     /locus_tag="ACOIAP_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639123.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIALGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVFSSFIGYYNNRLRKML
                     FKK"
     gene            complement(28465..29193)
                     /locus_tag="ACOIAP_002241"
     CDS             complement(28465..29193)
                     /locus_tag="ACOIAP_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2639124.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            29318..30406
                     /locus_tag="ACOIAP_002242"
     CDS             29318..30406
                     /locus_tag="ACOIAP_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639125.1"
                     /translation="MNFNFAKATNSRLMGSLGLMINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLKNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYNKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYDKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNIVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSDMNEGIFF
                     TRFNFNNDHVKENVYVINNDMKAIYYLMGNKFFIGTYDENDCNYINEISQSNYSDYIK
                     FEENFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(30844..>31151)
                     /locus_tag="ACOIAP_002243"
     CDS             complement(30844..>31151)
                     /locus_tag="ACOIAP_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639126.1"
                     /translation="GNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCNQNMPPNV
                     LMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSMQGIPQATNIEEFDEEEM"
BASE COUNT        12217 a         3166 c         5692 g        10076 t
ORIGIN      
        1 taattggcta gacttctttt aaaaaatatt ttaactataa ttgattttta tttaatcgaa
       61 aaaaatatta tgactataaa aaattgctac ttattgtttg aatatttttg tatataaata
      121 ataagtggca taaatttata tattaataat gatataatat aaattaatag ataagatata
      181 attttaaaag gagtgatata agatgagcaa atatagttct ttatgggaat atgttaagaa
      241 aaacaatagt caatcgttta aattaacttt tgaagaaata aaagatattg ctggagtaga
      301 gatagaccat tcgtttttga aatataaaaa ggaattaaat gaatatggat atcaagtagg
      361 aaaaatctct ttaaaagaga agactgttat tttcgataaa attggttaag acataaataa
      421 ttacatataa taaaataatt tgtattgaca actattaaaa ataaagtaaa tcttatataa
      481 gatttacttt atttttagag gctgcttttt ttaactttat actataaggt atataaaact
      541 aagcctatta aaaatgttat aatttctatt gctatcatag accatatcaa tccatcaagt
      601 tcataaaagt aattaatctt tattaaatag cttctttatt ataatttctt tatttcatat
      661 aatataaata gtattaaaat ttttatgaga gttagagtaa gcatgtatta ctacttaaat
      721 atttctataa tcaacatcta gtaatttacc tttttggtga aaatgattaa taagtttttt
      781 gggatgattc attattaatt catctggaaa attaatttcc tttaagatat tctcagaata
      841 ctcatagtta cctatgtcaa aacaaatgtg agcatctgaa gttagtatga ttttagcacc
      901 atattttttg caaagcgtag caatatactt acagttatcc gagctaccat ttcttgacac
      961 tcctttaata gaacaattat ttatttctat taagatattc ttttctatag ctaatttaat
     1021 gattaattca tagtcgattg ggtagtttgg gtttccaagg tgtcctaata tttcaatatt
     1081 atcatgctta tttattgcat ttattaaggc tttagtatta ttctctaatg tatttggtga
     1141 aaaaacggct tcgtgaaatg acaagataag ataatctaat cgaggaatta caaaaggctc
     1201 taggtctatg tttcctttag tgtctagtat atttgcttca catcctctta aaattataat
     1261 gttatttatg attcttggga tatttttaat gttgtgaaag taccatctgt ggggagaacc
     1321 aggcatctta ggaccatgtt cagatgtacc tagtatctta attccatttt ctttacaata
     1381 attaatattt tctaacaaag tgctatagcc atgaccactg actatagagt gggtgtgtaa
     1441 atctgataaa aaattcatat aaattcctcc tctataaaag atgagggtaa cgtaatttat
     1501 attataaaac gaatagaaaa gaaaatcaat agttacataa ttagacaaaa atattaaaat
     1561 attgtagaat taagcttaat aataaatgtt taacagtatt actgcttata ggggagggta
     1621 actatgacac aaagaaagct atcaaggaaa gaaaaagttt taatttgctt gaaaaggtta
     1681 acagaagaac acttgaactt taataatggc attagatttg gatttgatgc agaatatatt
     1741 gctactgaag taggtataaa tagaagtaat gctagtaagg aattaaatca attaataaaa
     1801 gaaagtatta ttataaagat aaagggaaag cctgttcaat acttatacaa agaaagtatt
     1861 gagagcattt taggaaagaa actaaataaa gggatattta gtaatattaa ctctataaat
     1921 gaatatagtg aagatgattc tatcaaagat gagtatatct tagaaggtat aaaaaaagag
     1981 aacaatattt ttaatttagt aggatgtgat ggaagtttaa agtcccaaat agaacaggct
     2041 aaagcagcag taatatatcc acctaagggg ttgagtacat taataatagg acctacagga
     2101 gttggtaaat ctatatttgc agaatatatg tataagtata gtttgaatat aaaagaagat
     2161 agtgataatg caccatttat catatttaac tgtgctgatt attctgataa tcagcaatta
     2221 ttgttagcac agctttttgg atatgtaaaa ggagcattta ctggagctga taaagacaag
     2281 tatggtattg tgcatgaagc taataatggg atattgtttt tagatgaagt tcataggtta
     2341 tctgcagagg gacaagaaat gctatttctg cttatggata aaggtatata tagaaggtta
     2401 ggagaggcta ataaggtaca tgagtgtagg gttatgataa ttgcagctac tacagaagac
     2461 ccagaaacag caatgctgga aacgttttta agaagaatac ctgtaactat aaagattccg
     2521 tctttagagg aaagaggttt tcaagagaga atgaaactta tatgttattt ttttaaagaa
     2581 gagagtatta ggattggtgt taagttaaag gtttcaaaag aagttattaa ggcatttatt
     2641 ttatataagt gtaagggaaa cataggacaa ttaaaaagcg atatacaatt aatttgtgca
     2701 agagcttttt tagattatat gacctataaa agggaatgtg tatatgtaag gctctctctt
     2761 ctaccaaaca atattagaga atcattatat ggaaataata gaaaagagga gtttgtacaa
     2821 aatttcagtt ttattgggaa agatgatatt atttttttac cagaagaaaa gagttttgaa
     2881 agtgaaaatt tattaataga aaataaaaaa tatgatttag atttctatgg aatgataaaa
     2941 gaaacttgga ataaacttca acaagaaggt attaaagagt cacaaattag aagtgttata
     3001 gatgaagata tacagaagta ttcctacaat ttaatgaata cttttatcta taatagtagt
     3061 aatcaaacag cttataacaa cattgttaat gattcaatcg caactactgt gaagtatgtt
     3121 ttacaaaagc atgataaatg gagcaaaaga gaaggattag ataaattaat aaaagctata
     3181 gccttacata ttcagaattt aattgaaaga ataaagattg ggaacatagt aaagcatcct
     3241 aataaagatg aaattatgaa ggaaagagca tatgaatata acatagcaaa agaaatatta
     3301 tctaacatgt cattaatgta tggagttgag tttccagaag atgaagcaat ttttttagca
     3361 acgtttcttt atttatctta tgtgggatta aatgaggaaa gtatagcaat attagtcata
     3421 atgcatggtg aatctacagc ctctagcatg gtgaatgtag ctaatacttt actggattgt
     3481 aaccatgcag tggcaatcaa tatgggatta gaagatagag ttcaggatat tttagtacaa
     3541 gctgtagaaa tagccaatga aattgacaaa ggaaagggaa ttttaatctt aaccgatatg
     3601 gggtctattt taacatttgc taaagttatt catgatgcta caggaaaaga agtaaaagca
     3661 atagatatgg taagtacacc tattgtaata gaagcaacta gaaaggctct aactccagaa
     3721 atgacattag agaaattata ttttaatatt atagaatcta taaagaaaca ttatggagat
     3781 atggaaatta catatgctga aaaagataat ggtggtagat attttgatag attactaatt
     3841 gataatatta gtaaaacttt gactttttta aacggggaaa aggcttattt tatattaaaa
     3901 gaagtaatta atagaattag tgaacattat tctttagtaa ttcaagatga gcttttagta
     3961 aagtttatat ttcattgttc ctgtatgatt gaaagagtaa taataaaaga gtctttagtt
     4021 tataaatcat atgaagaaag aattagtaga agtaaagaat tatatttagt tataaaagaa
     4081 agttttaagc tagtagaaga gacattcgat ataattattt cagatatgga atatgcaaat
     4141 atattagata tatttgaatc acaatatgat acagataaat tcaaaagttg atacaaaatt
     4201 taaaaatagc caaaaggcta tctttttttt actttttttg atacagattt gatacaagtt
     4261 ggaaaaatct tttgatacat attgatatag taagtttttt aaaaaattta agcaaaaagg
     4321 tttgattaaa tcctgtaaaa tagccatttg ttattgatac acataagttg gcacggcaat
     4381 tgcttgtata aaaaatgaca agaaaagtga ggtgaaattg gtgataggaa taatagttat
     4441 gactcatggg agttttagtg aagaaattat aaaaagctgt gaacttattg caggaccagc
     4501 agaaagaaca gcagcaatta aactaaatag gaatgataat attgaagact taaataaaaa
     4561 ttttgtagaa aagttaaatg aactagatga aggtgacgga gttttagtat tagctgacct
     4621 attaggaggt tcgccaagta atgttgcaag tttaaacctt aaaaaaggtg gaaagtttca
     4681 tgcacttact ggagtaaatc ttccaatgct acttgaagct ttaattaata gagagggaaa
     4741 aagtttagag gagttagcag aagcatgtat tgaagcagga caaactggta taaacaatat
     4801 taataaagtt cttagctcaa tgtaatagaa aaaggagttt gattaaaaat gtctttagta
     4861 aaatattgca gatgtgatga tagattaata catggtcaag tgatatataa atgggttaag
     4921 catctaggtg taaaaaagat agtagtagta gatgatgaaa ccaccaatga tgttattgct
     4981 aaaggtttga taaaaatggc agcaccaaag aatattgatt tatcaatatt aactgtaagt
     5041 gaatcaagga gatattttta taataatcaa gctgatgata acgtttttgt attaattaaa
     5101 aatttagata ctgcaaatag aatgatagaa gaagggatta atatcaaaaa acttattgtt
     5161 ggaagaatac ctacaggaat aggaaaaaag aaaatatctc aaaatgtata cattaataaa
     5221 aaagagtttc ttttaataga tgaatttatt aaaaaaaata ttaatgtatc aattcaaatg
     5281 gtacctgacg aagaagaaat agaattaaac cacaatatta atcgctataa aggagagttt
     5341 atttagcaat gaataaatat aaggtaatca tactctgtca tggaacttgg ggaaagttat
     5401 tagtagaaga aacaaataaa aactttggat tgtcaaatca atatgaagtt ttatcattaa
     5461 gttctgaaaa agatgtttct gtattcatga aaggggttga agaagcagta gataaagaag
     5521 atgtgaaaat tataatatca gatttatatg gagggtctac atcaagtgtt gcaatatctg
     5581 ttgctataag aagaggaata gatgcaataa atggacttag cttacagaca attttaatcg
     5641 tagatgagga attaagtaaa gaagataaat tacatacatt accagaaaga atagtcaaaa
     5701 aaaataataa tctttgtgtg gatttaatta aagagtttaa aaaaatataa attatgaggt
     5761 gaatataatg gcaaaaataa cattagtaag agtagaccac agattaattc atggacaagt
     5821 tataacaaaa tgggtaaaaa tcgctcaagc tcaaaaaata ataatagttg atgacttctt
     5881 aggtcaagat gaatttatgg ctgacatata taaaatggcg gcaccatcag gagtggaagt
     5941 agttatttta acagcagaag atgcaggaca agcattccaa aacaacactt taggagataa
     6001 aaatatattt attctattta aaaatgttga tatggcaaat aaggcttata aagctggact
     6061 taaatatgaa aagattcaat taggaggtat tccaaatgaa gcaggaaaga agatggtatt
     6121 tacagctgtt tcattaggaa gtgaagatat aaaacaactt aatgaactta atgaaaatgg
     6181 agttgagata gtattacaag ttataccaga ggaatcatct atgacatatg aaaatgcatt
     6241 aaagaaattt aaataaaaaa tataaattag gaggaattat aaatggaatc tgttttgatg
     6301 ttggcaattg taacaggatt atggtattgg tttgcagcag gtcttgcagg gtataccctt
     6361 ttctcaacac taaagtctcc tttatttata ggttttagcc ttggattact ttggggtgat
     6421 gtaacaactg gtatgattgt tggtgcaagt atagaaatgg tttatctagg aatggtcgca
     6481 gcaggaggaa atattccatc agataaatgt ctagctgctc ttattgcaat accagtagca
     6541 cttcaaactg gtgttaatgc agaagttgca gtatctattg cggtaccttt aggcgttata
     6601 ggagtattag ttaataactt aagaagaact ggtaatgctg tattagttca taaggcagat
     6661 aagtatgctg aagaaggtaa tacaaaaggt atctggagat gtgcaacact ttattctttg
     6721 atatttgggt ttgttttaag atttccaata gtttttgtat gtaacttttt tggagcagat
     6781 ttagttcaat cattattaaa tgttatacca caatggttaa tgaatggatt aacagtaatg
     6841 ggaggtatat tacctgcatt aggttttgca acaacaatat ttactatagg taaaaataaa
     6901 ttcttaccaa tgtttattat aggatttttt atggttcaat attttgaaat atcaattact
     6961 gcagctgcaa tatttggtgt ttgtatagct cttttaatta cctttatgaa agaagacaaa
     7021 agggtaggtg aagtataatg caagaaataa aaaataaaga cgttaaaaat ggacaaggta
     7081 caactgaagt taataagaca agagtactta caaagaaaga tgtaacaaaa acatacctaa
     7141 gatggtggtg gacagcagaa ttatctaact cttttgaaag aatgcaagca ttagcagttt
     7201 gtgcaagttt cactccagct ttagaaaagt tatataagaa aaaagaagat ttagtagatg
     7261 cgttaaagag acacttacaa ttttttaata ctcaagctat atggggaggg ttaattcacg
     7321 gtacagtttt agctatggaa gaagagaaag ctactgaagg aaaaatccca ggagaggtca
     7381 tttcaggtgt taagaatggt cttatgggac ctttggctgg aattggagat actttagatt
     7441 ttggtacatt tcaaacaata ttcttagcgt taggtgcttc atttggagca gaaggaagtg
     7501 ttataggtgc atttttccca ataatcttta gtatattact attttgcgaa ggttattact
     7561 tattccattt aggatattct ttaggtagag attcaattaa gaaaattcta tcaggtggta
     7621 ttgtcaataa gataattgat ggcgcttcaa ttttaggaat gtttatgatg ggagcattat
     7681 ctgcaactac agttaagctt tcaactccgc tatcatttga tattggtggt aaagcaattg
     7741 ttgttcaaga tacattaaat atgattgctc caggtttatt accacttagt gttgtattct
     7801 tcgtatattg gggaatgaaa tacaagaagt ggacaataac taagttatta gtaattttag
     7861 ttgtattggc attagtagga tcattcattg gaatattcta atttacaatg attaaaatat
     7921 agaatttaat tttaggagga gaaagaaatg tcagaaaaaa tgtatacaga aaaggaatat
     7981 ttagaaggaa ttagaggagc aacaggagaa agagcagtat ggttctatct tcttatgaaa
     8041 gaagctgaaa aattaggagt taatccagat gatatatgta aagaagcaat atatggattt
     8101 ggtaaaatga gaggtcaaaa atatagcgta gcagacactc caggaaaaat ggcagaaatg
     8161 ttatataaca gtaaaggaca aaaagtattt gaaatggaat tagtagaaaa tacagatgag
     8221 aatggagttt taaaattcca tcactgtcca ttagatgcag cctggaaaga atatggatta
     8281 actaaagaag aaagaaaaga aatttgtaga ttagcttgtt acggtgatta tggaagagtt
     8341 gactgtgcac aaagtgttag attagagttt gctcaaaaac gtgctcatga tgatgaagtt
     8401 tgtgaattag tattcacaag aaaataattt ttaatgctaa aagcctgttc tttaaggaca
     8461 ggctttaaaa agatagaaag taggttactt tatggatata agcagaagag tagataatag
     8521 tttaaataga accatagaat ttctaaaaga attaataaaa attgactcac aacaaggtga
     8581 acctatttta caatgtcctt ttggtatagg acctaaaaaa tctttagaga aaactttaga
     8641 ttactgtgct agtttaggtt ttagtgttaa gaatattgat aattatattg gatatgcaga
     8701 aattggagaa ggaaaggagt taatagggat tccaatgcat ttagatgtag ttccaccagg
     8761 agacgggtgg agcgtagacc cattttcggg agtagtaatt gacaatatta tttatggaag
     8821 aggtgccgta gataataagg gggctgtatc tatgcttata catgtattga aaaacataga
     8881 ggatatgtac cctacaatta ataaaagaat aagattaatt tttggtacaa atgaggaaac
     8941 aggcatggaa tgtatcaaat attacttaga taaaggtgaa gaaatcccaa gtatgggatt
     9001 tactccagat gctatgtatc cagtagttaa tggagaaaaa ggaagagttc atataaggat
     9061 agaaaaagag attaaaattg ataaaagtaa accttacata atattaaggg gaggaactaa
     9121 agaaaatgtt gttccatctc attgtactgc aaaaattgtt aatggaatta ttttagagct
     9181 aaccactaaa ggagtagctg tacatgcaag taatcctgaa aagggagaaa atgctatatc
     9241 taaaatggta ataaagatat tgaaagataa tatgaatttt cagcatagag aagatataga
     9301 attagtttca aaataccttt gtagtgacta ttatggaaat gcattaggga ttaatcgata
     9361 tgatggggta ttcaaaaaca ctaccttaaa tttaggaata ttaaaagtaa atgaggaaaa
     9421 aattgtatgt gagttggata taaggtatgg taaaaatata attttaaaca atataataga
     9481 tagattcaaa aagttttttt gtaatggttg gaaaatagag gttattgccc ataaagactt
     9541 acattatgtg gatgagagta atttagtact taaaaaatta ttagaagcat atgaagaagt
     9601 aacagatgaa aatggatata caattgctat gggtggtggc acatatgcaa gttggtttaa
     9661 agatatggtg gcgtttggac ctaagttttt agcgtataaa actggtggtc atggagtaga
     9721 cgaaagagta ccaataaatc atatacgaaa gaatatggag atatatacct tggctttaat
     9781 aaaactatta gaattgtaaa aagagaagag attttatgtg aaaatgtacg gatatcttaa
     9841 aaagagagat aaaacgagtt taactttatt taaatgttca acaccatcaa atggggctgt
     9901 ctcaaaatat agataagtct cttccttatt gttgaaatga tgaattttac ttcatacaaa
     9961 aaagagtgtc ttatgaagta aaatgttcat tttgaaacac actcatttga tgatgttgaa
    10021 gagaaaataa gtatgaaatt attaaaaaag atgattttat aaaagttaag gttgaaaagt
    10081 taattgaatg gaattagcta aatggagaag gctatatact atctaataaa ataataaaaa
    10141 agtgttgtaa aattggttat atgattagag aaaagtctat tgatatttat tcagacagtg
    10201 gatgggaatt tatggtttgg gatgaaaatg gagaataata aaaagtatag tttatacaat
    10261 ttaataagat atatgtacaa gcagttaata taaatgattg actgcttttc ttttatagat
    10321 ttttatataa tagacaatta ctaatacatg atagttgcct attataatta taagaataaa
    10381 tacgaataat aattttataa aagaattaaa tggaaaattg aagagttata ttcaggattt
    10441 taaaaagaat atgaaatgag aaatgaaaat aaggtgcttt atattaaaag atattttata
    10501 caaaatattt aaaaacgtga taaataaaac tgtatttaga tagattaatt actagtttta
    10561 tatagaatat ggattttgtt tacaaaatta gaatatttta caagttattt ttaaaaaata
    10621 tttaaatata tattttagat atttgtttct ctgtggttga ttttttcgtc aaaagtcaac
    10681 ttcaaatcgc ttgttagctt tatgtgttta aggatataat tatacataag gagggattga
    10741 catgaatgaa ttaaacatcg caaaaacgct gattttaaag cgtaaagaaa aaggaattac
    10801 acaagatgaa cttgcaaatt atataggcgt ttctaaagct tctgtatcta aatgggaaac
    10861 tggacaaagt tatcttgaca taaccttttt accgcaactc gcgacatatt tcaacattac
    10921 agttgatgag ttaatatgct atgaacctca aatgatgaag gaagatatta ataaactata
    10981 caataaactg tgcaaagact ttacggctaa accatttgat gaagtcatga ttgaaataag
    11041 agaaatcata aaaagatatt attcatgttt tcctttgatt tttcggatgg gtcttttaat
    11101 agtcaatcac tatgacattg tagatgaaaa aaagcgtgaa ctattaattg atgaagcatt
    11161 ggaaatattt attcgtatac aggaaacttg taatgatata gatatttgcc gtcaagcaaa
    11221 aaatatggag gcaacttgtt atatattgtt aaatcaaccc atacaagtga ttgatttatt
    11281 gcaaaatagc aattttccca tgataaatga atctatactt cttgcacagg ggcaaatgat
    11341 gaatggtcaa attgatgaag caagagaaac atttcaactt ggggcatatc agaatcttat
    11401 atcactagtt caaaatctag tgggtatttt gcaaaatgca gataaattac aaatgaaaga
    11461 aatagaaaga cgtattctag caatttcaaa tatatttgaa cttgatacat tatctcctgc
    11521 tactatgctt tctgcatatt taacacagac acaaattaat ttaatacatg aggataatga
    11581 aggagctatt aaatcattac gaaaatatgt agatttagca acaagtgata tatacccaat
    11641 tacaatacat ggtgatgact tttttgataa acttgacaga tggatttctg aaattggaat
    11701 aggtattaca cgtgatgata caatcgtaaa agcgggtatt gttgctgcta ttaaaaataa
    11761 tccaatgttt tctgtattaa gtgaaaacaa agaatacaaa tttcttatag aaaaattatc
    11821 tttattggag gaataagatt atggaaaatt tgatggaata cttaccactt ttgattcctg
    11881 ttattatttt agatttaatt cttataatta ctgcacttgt tcatgtattg agacatccaa
    11941 attataaaat tggaaataaa gcaatatgga ttattgtagt gctgtttatt agcataatag
    12001 gaccaatttt gtattttaca ataggaagag gtgaagaatg atgaatattg tctcaataaa
    12061 tgggttatca aaaggttttg gtaatcgaaa gataatagat aatctaaatt ttactgtacc
    12121 agaagggtca gtctttgggt ttgtaggtaa gaatggtgca ggtaagacta caacaatgaa
    12181 aatggtactt gggttacttg aaccagatag tggaactata gatgtttgtg gtgagaaagt
    12241 gacctatgga ggaacaagtt ctaatcgtca tgtaggttat ctgcctgatg ttccagagtt
    12301 ttacaactat atgagaccac ttgaatatct ttctctttgt ggcgaaatta cgggactttc
    12361 aaaacaagaa ataaagataa ggagtgaaga gttgttatca cttgtgggac ttggcaatga
    12421 aaagagacga ataggtggat tttctcgtgg aatgaagcaa cgacttggta tagctcaagc
    12481 tttgctttca cgtcccaaat tacttatttg tgatgaacca acaagtgcac ttgaccctgt
    12541 tggtcgaaaa gaaatactag atattatgct taaaatcaaa gactcaacaa ctgtaatatt
    12601 ttcaacacat atactatcag atgttgaaag aatctgtgac catgttgcta tattaaacaa
    12661 aggaagcatt gctcttagtg gtacactttc agaaataaaa agtatgcacg gaaaggatag
    12721 acttttactg gagtttgcaa gtaatgatga aattcaaaag tttaagtcta gtggtgacat
    12781 taaatcctta ctaaaatatt cagaagaaac taatatggaa attgttttgc atggtaaaga
    12841 tataaaagca atacaaaaaa cagttatatc tacactcgca gaaatgaatc tttgtccagt
    12901 aaagatggaa ctaatagaat tgtcacttga aaatttattt ttggaggtag taaagtgaga
    12961 gaatacatag catttacaaa aaaagaattt aaggagaact taagaaatta taaattattt
    13021 agtttgatta ttttattttt agtatttgga ataatgagtc ctctttctgc aaaatttatg
    13081 ccagacttga ttgctcattt tgctccaact ttaaaagtta ctactgcacc aactgcttta
    13141 gattcttgga cacagttttc tggcaatatt tctggacttg gagcgagttt aactctaatt
    13201 gttttttgta atattttatc aaacgaatac tctaaaggaa cactcgttat tatgttgact
    13261 aaagggttat cacgttcatc tgtgatattg tctaaatttt ctattgcagt aatcattatg
    13321 acaattggtt tttggttgag ttttttatgt acttatggat atacaatgta tttttggcca
    13381 actgaaaatc ttaatcatat tatattttca gcatttaact tatggttaat taatattatg
    13441 tatattacca tattaattct tgggtgtgta ttatttagac cagcatttgc aagtgtgtta
    13501 cttgtattag tagcaactct tattttgagt ttgatttcta ttcctaaaca gattgcacct
    13561 tatacgccta atttcatatt atcaaaaaat atagatttgg tttcaggtaa agtggcagct
    13621 ccagaattta ttattccaat gattgtaaca attgttattt cgataatatg tttgttatta
    13681 gctgtcattt tatttaagaa aaaagcagtt taaggatatt tttattatta aatataaata
    13741 gtactgtatt atggaaaaat gtgtttagtg ttgtagaaga atatatttaa gtaaaaagag
    13801 gttgtctcaa aatagagata taagcctctt ttttattgtt aaaattataa aaacatattt
    13861 gatttcatac aaaacaagta tctcataagc taaaaaattc attttgagac atttcttttt
    13921 ttattttagt cattctcatt gtactttata ataattaagt tattacctta gggaattgtt
    13981 taaaaataaa aaagagaagg attataatct aatgattata agttatttaa gctatgttta
    14041 gtatatagag tctaaagtag taaaggatta aaataatatt gtttatatca aataaagata
    14101 agaatcttta attgtggtaa aatatactaa aaaatcactt taaaagtgat aaaattattt
    14161 taagtaaata ttttaaaggg gtgtagatat ggaaaagtca aaagtatatt tttgtgattt
    14221 atattcaaat tcgcaaaata aaaatgtacc aaataatgta agaagattat ttgataaagc
    14281 aggattcaag gatttaatag aaaagaatga ccaagttgca attaaacttc actttggaga
    14341 aaaaggaaat actacatata tgagtcctgt ggcagttaga caagtggttg ataaggttaa
    14401 agagtgtgaa ggaaagccat ttttaacaga tacaaataca ctatatacag ggagtagaac
    14461 aaattctgta gaccatctta caactgctat agaaaatgga tttgcttatg cagttgtaaa
    14521 tgcaccagta ataattgcag atggattata tagtagaaat tatgagaatg taaagataga
    14581 taaaaaacat tttgaaagtg taaaaatagg tggagaaatt tataattcct ctgcaatgat
    14641 agtaatgagt cattttaaag gtcatgaagc agcaggattt ggaggagcat taaaaaacct
    14701 agctatggga tgtgcaagtg cagcaggaaa acaaatgcaa cattctgatg ttaccccagt
    14761 agtaaaggaa aagaagtgta taggttgtgg aaagtgtgtt aattcttgtc ctacaaaagc
    14821 tataagtata gtggataaaa aagcagttat agattctgat gtatgttatg gatgtggaga
    14881 atgtccaact gtctgtccaa ctagagcagt aactatacaa tgggaaagtg actcagatgt
    14941 gtttgtcgaa aagatggcag aatatgctta tggagcagta tcaaataaaa aagacaagat
    15001 aggatatata acttttgtta tgaatgtaac tccactttgt gattgtgtac cttggtcagg
    15061 tagaccaatt gcccatgata taggaatatt agcatcaaca gatcctgtag ctattgaaca
    15121 agcatgttac gatttgattt gcaaggaaat gggtcatgat gttttcaaac atgaacatcc
    15181 tcatgtaaat ggaactagaa taatagatta tgcatgtgaa atgggtatgg gaagtaaaga
    15241 atatgaatta ataaaattat aagaatagta gtacttaaat gcatataatt attgtaagag
    15301 aaatctaaaa gtatcaaagg agtatgcatt tatgaaaatt tactatgaga aagaaaacag
    15361 caagaaggcc aatgtaaaca atattccaag tgtatttgcg tttaattttc taagaaactt
    15421 tttgactagc aaagagtatg aggaaactag aaaagaatat tttataaata atctaacaaa
    15481 aagtcaggtt aatcaagcta tgaaggattt aaaatggcta tttagagaat atgaaggctt
    15541 agaggtcatt acaatggaaa gcttggatgg agttaagaca aggatagttt tataaactag
    15601 caagaattat attttaataa aaaatactgt ttcaataata atatgtataa tccatgtact
    15661 aatattattt tgaagcagta tttttttgca aatagtaaac ttatacataa aataaagttg
    15721 accaataaat attaagtatg taatactata tataataggt aaactaaata taggtattaa
    15781 gttgacaaat aggagggtat atggaaaaat acataataaa attaaaaaat aaagtattgg
    15841 gaggaaaaga aataagttat gaagaagctc ttaatttaat aagtcttgat acaaataata
    15901 agaacgattt tgatattcta ttaaaatctg caaatgaaat aagagaattt tttatgggaa
    15961 gaaaagcaga tttatgtacg ataattaatg ctaaatctgg caaatgtagt gaagactgta
    16021 aattttgtgc ccagtcatct cattataaaa ctggtgtaga agaatattca ttgttagatt
    16081 acaatgaaat cttaaataga gctaaagaga tggagagtaa aggagtacat agattttcat
    16141 tggttacaag tggcaaaggt atgtcaggaa aggagtttaa tgatatttta aaaatctatg
    16201 aaagattgag ggaaaatact aatttaaaat tatgtgcatc tttaggaatt atagattatg
    16261 agcaagctaa aatgttgaaa tcagtaggtg taactacgta tcatcacaat gttgaaacgg
    16321 ctagagataa ttttcataat atatgtacaa cacacactta taaagatagg ataaaaacga
    16381 taaaagaggc taaagaagct gggctagatg tatgtgtagg tggtataatt ggaatgaatg
    16441 agagtgaaga acagagacta aaaatggctt ttgaaatacg agaattaaat gttaaatcat
    16501 ttccaataaa tattttaaat cctattaaga atacaccaat ggaagattat gatgtattag
    16561 aaccaatgga aatattaaaa acaacagcag tatttaggtt tataattcct aatgtatata
    16621 taagatatgc tggtggaagg ctatcattaa agggatatga tgaagttgga tttaatggag
    16681 gagtaaattc tgccattgtt ggtgattatt tgacaactgt tggaaatggc attgaaaatg
    16741 ataaaaaaat gattatagag caaggatttg aaatttaata aatattactt aaattaatta
    16801 atatactttt agataattat aaaagtatat taattttttt tgtggattaa tttaaatatt
    16861 aaatttgaat tataaattgc aatattttga aaaaagggaa aaatatcaaa atttatataa
    16921 aatagttgca aaggaaaaaa agatgtgata gtatctaggt aaccggttaa gtaaaacggt
    16981 ttcctaaatt gtgggggtga acttcttgag tataacaata aaagaaattg gcgaattggc
    17041 tggtgtttct aaaacaactg tgtcaaaagt cattaataat aaagatgaaa acataagcca
    17101 ggcaacaaga gaaaaaattt tgaaaataat gaaagaaaaa aattatgtgc caaataaatt
    17161 agcacaaagt ttagtaacta aaaaaactaa tactataggg cttcttatac cagatatacg
    17221 aaatccattc tttacagatg tatcaagagg tgtagaagat aaagccaata aagaaggcta
    17281 caatataatt ttatgcaata cagatgaaga tgctaaaaaa gaatatgaag gaataagaac
    17341 gctatcagag aggatgatag atggaattat atttgcagcc tcttcaaata caaactggaa
    17401 agaagcaaat tataaagata taaaaatacc aactgtgttg attgataaga agataagcat
    17461 gaacaaagaa accttaaaag gaattgttaa aataaataac tttgaagggg cctatatagc
    17521 tacaaaatat ttattagata ctggaaataa gaaaataata tacctaagtg gtccacttca
    17581 aaatgaaata gctatagata gattagaagg atataaaaag gctctaatcg agtgtaattt
    17641 aagctacaat actgattatg tatttgaagg aaaatataag attgaatggg gacaagaatt
    17701 tataaaaaat ttagaaaaga tagattttga tgcaatattt tgtgcaaatg atttgattgc
    17761 aataggtgtc ataagaggtc ttaaagaaag aggattaagt ataccaaatg atgtgagtgt
    17821 tgtgggattt gatgatattc aaacatcaag tctaataagt ccttctctta ccacagtaag
    17881 acaaccatct tatgatatag gatataaagc cagtgaaata ttgataaatt gtttaaaggg
    17941 agataaaaaa gaatcgtttg atgaattgat tttcaaacca gaactagtca taagagattc
    18001 gacaaaagaa agtgaataac agcatgaaag acataaatag atatgtaaag gagtaatgta
    18061 atgggaaaca tagttgtaat aggaagtgta aacatggaca tggtatgttc tgtagataaa
    18121 agaccagaaa aaggagaaac agtattaggt aatagttttt ttacatcacc tgggggaaaa
    18181 ggtgctaatc aagctatctc agcttctaaa ctaggagcaa atgtaaaaat gatatcatgt
    18241 gtaggggaag atagcctagg agaggagtta ataagaaatt ttagaaccaa taaagttgat
    18301 tatagcttag tatccagaaa taagcataaa agctctggtg ttgctgttat aacattatgt
    18361 gaaaatgata atagtattgt tgttgtacca gggacgaatg agttagtaga tatagaatta
    18421 attaagaaga atgaagaaga gataaagaat gcagatatag tattgttaca attagagatt
    18481 ccattaaaaa caataaatta tgtagtaaat ttctgttttg aaaatagaat taatgtttta
    18541 ttaaatccag caccagcaat aaaattagat gaagatataa tagagaaagt aacttattta
    18601 acaccgaatg aacatgaata taagatagtt tttgacacaa atgaagagat agaagaagta
    18661 ttaaaaaaat atccaaataa acttgtaata acagaaggaa aaaatggagc tagattttat
    18721 gatggaaatg aagttaaaca tgtatcttgt ataagtgttg atgtccaaga taccacagga
    18781 gcaggagata catttaatgg agctttggca gtagccataa cagaaggtaa aaatctatat
    18841 acagcagtag aatatgcagt agtagtatca ggtctttctg taacgaaatt aggtgcacaa
    18901 tctggtatgc cttataaaga agaggttgaa aaatatttaa ataacaataa ataaaaatct
    18961 aatttgttca aatttaaaac tattaaaagt ggaggttaat tatgaaagtg agaaaaattt
    19021 tatctttagg aattgctgga atactagcaa taggaatgtt aacagggtgt tcaatggaag
    19081 gaccaagtaa atcagacaat aaaggtgctt cagacaagaa agatttaact attggagtat
    19141 ctacaataac tcttcaacat caatttttta tagatattga tgagggaata aaagaaaaag
    19201 ctaaagaatt aggtgtaaaa gttatagtaa atgacccaga ccaagatgta gctaagcaaa
    19261 catcagcaat agaagatttt atacaacaaa atgtagatgg aatgatagta cttggaacag
    19321 ataactcggc tatagtaccg gcagtagaag gagcatttga aaaaatgcct gtagttacag
    19381 ttgatgctgt attaaatact gaaaatatta caagttatgt aggaacagtt agttatgatg
    19441 ctggtaaaaa attaggggaa tacactaaaa aatacataga tgaaaaatta ggtggaaagt
    19501 cagaaatagc aatagtaaca gatttaaaat ctcaaataca aatgcagaga atagatggat
    19561 ttaaagatgc attaaaaggt tcagcaaatg ttaagatatt aaattcacaa ccaggatatg
    19621 acagagaaga atctcttaat acagtagaaa acttaattca atctaatcca gatgtagata
    19681 taatatatgc aacagctgaa aatagtgtac taggagctaa agctgcactt gaatctgcaa
    19741 aaaataagga tgttaagatt gtaggatttg acttaactga agaagcatca agtggaataa
    19801 cagatggaac tattcttgct atgattcagc aacagcctaa agagatggga cgtttagctg
    19861 tagaagcagt agtaaaagct ataaaagggg aaaaggtaga aaaaaatata ccagtcccag
    19921 ctttacttta tgataaggaa aatataaaag actttaagaa ttagcaaaaa aaatgagatt
    19981 atttgaaaga aatcctattt aaaaaggagt gtcattatga gtaatataat tctgaagtta
    20041 agcaatattg ctaaagaatt tcctggtgtc aaagcattag ataatgttaa ttttgagtta
    20101 tttcatggcg aagttcatgc actactgggt gaaaatggtg ctggtaaatc aacaatgata
    20161 aagattttaa ctggtgcaca ttcgaaaact tctggaaaat tcatttttca agataaagaa
    20221 atagagaata tatccccaga tgtctctaaa aagataggta taaacgccat atatcaagaa
    20281 ttaacagtct ttgatgaatt aacagtagca caaaatattt ttatgggaaa ggaaataaat
    20341 ggcaaagtat taaccaatga caaaaaaatg aatgaagagg ctaaaaagat tttcgataat
    20401 atgggaatag atgtaaatcc aaatagtcta gtcaaagagc ttagtatagc tcaaaaacaa
    20461 atggtagaaa tagcaagagt tttatcatca gaaactaaag tattaataat ggatgaacct
    20521 acttcttcaa taagcaaaaa agagactgaa atacttttta gacttataaa ggacctaaaa
    20581 gatagtggag ttagtataat atatatctct cataggatgg aagaactttt tgagatttgt
    20641 gacagaataa ctataatgcg agatgggaaa acggtttcga ctttgaatac caaagatgta
    20701 tcatctgagg aagaattagt taatttgatg atagatagaa agttagacca attttttccg
    20761 aagagaaaag tagaaataaa agaagaaatt atgagagtgg aaaacttaac taagaacaat
    20821 gtttttaatg atgttagttt taatataaga aaaggcgaga tattgggaat aggtggacta
    20881 gttggaagta agagaagtga gatagtagaa gctatatttg gacttagaac atatgattct
    20941 gggaaaatat atttaaacaa tgaagaagta aagtttaaaa ctccatcaga tgcaatagaa
    21001 aatggactag gattgataac agaagataga aaaggtactg gattgttttt acaaatgagt
    21061 gtcaaagaaa acacaactat ggctgggtta aaaaagatat ctaagtttaa atcaattata
    21121 gatagaaaaa aggaaaaaga gattttagaa aaatacatag aagctttaag gataaaaaca
    21181 ccacatatga atcaggttat acaaagttta agtggtggaa accaacaaaa agctataata
    21241 gcaaggtggc ttttattaca accagatata ttaattatgg atgaaccaac cagaggtata
    21301 gatgtaaatg ctaaggcaga gatatacaat ctaatgggaa atttagtaga gagtggagta
    21361 agtataataa tgatatcttc tgaaatacca gaattaatat caatgagtga cagaataatg
    21421 gttatgagag aaggtcatat aagtggattt ttagaaggtg aagaaatggt tgaaaataat
    21481 gtattaaaat tggctttcgg aggtaaaatt aatgagttca ataactaagc ataaagaaga
    21541 aaaatcttct ccattattga caaaattaac aagtgcattt agagaccaag gaagtgcagc
    21601 tgtaggactt gtaataattt ttataataat gagtatagct tcatctaact ttttaacttt
    21661 agataattta attaatgttg gaagacaaat atcaataaat gcaatacttg cagttggtat
    21721 gacatttgta ataatcacag gaggaataga tttaagtgta ggagcagtaa ttgctttagt
    21781 aggtacattt tgggctacaa cagtagtgaa ttataatgca cctatatggt taggtatgat
    21841 acttgcatta gcaataggga caatactagg agtcataaag ggtgcaatta tttcaacaca
    21901 aaaactacca ccattcattg taactttagc catgttaacg ataataagtg gggcaagttt
    21961 tgtatttaca ggaggaagac ctatatcagt aaatacagat gcatttaaga tgctaggtag
    22021 aggatatgtt ggaccaatac caataccagt tataattatg attatagttg taatagcagg
    22081 acattttctg ttaaaaagaa ctaattttgg acgtcatgta catgcagtag gtggaaatga
    22141 agaggctgct agattatgtg gagtgaaagt aaataaagtt atagtaaaag tatacgcact
    22201 agctggacta ctaacagcat tagctgggat aatactatca tcacgtttgg catcaggttc
    22261 accaactgtt ggagatggag cagaattgga tgctatagca gccgttgtgc ttggtggtac
    22321 taatatgatg ggtggttctg gttctatagt aggtacatgt ataggtgttg ggataatagg
    22381 aatattagga aatggattaa acttattaag tgtatcttca tataatcaaa tgattataaa
    22441 aggtttggta atgttatttg ctatatggat aaataatata aaattaaaaa aattagctaa
    22501 atctaaatag caattaaatt ttagtttata aactataaaa attattaagt ttttgtatat
    22561 atttttatac tttaatttgc atatatcttt atacattaaa tgggaatatg ctaagtgaaa
    22621 aagtttacta tggcttaaat agatgagatt agacttgaaa ttttaaatgt aaaaataaat
    22681 cttaggagga aatatgaaaa aaattctctt agatacatta aatagtaaaa aacaagaata
    22741 tatagattat ttaaaagaac ttgtaagtat aaagactgaa gatgttggtc atggaatact
    22801 aggtggattt gaaaaagaag gacaggaata tattgaaaaa cttgcaaatt acataggttt
    22861 tagtgtagat agacaagaaa tgagcgaaga attaattaaa aaagcaaaaa atatatataa
    22921 agaaggaaat ctaggtcaca attatcaaga tagatataat ttgatttgta agtatagtga
    22981 tgatttacct ggaaagacaa ttgtatttaa tggtcatgta gacactatgc caccaggtga
    23041 tataagtaag tggaaatata atccatatcg tgctacagaa gataatggaa aactttatgg
    23101 tcttggaatt gctgatatga aatctggact tatagcatca atattagctg taaagcttat
    23161 aaaagatagt ggtctaaatg tgcctggtaa tgtaaaaata atgtcagtag tagatgaaga
    23221 aggtggagga aatggtacca taaatgcagt tatgaatggt attgatggag attgttgcat
    23281 aatttgtgaa ccatcagaac ataacttaat agttgcacat atgggatttg tattctttga
    23341 agttgaagtt aaaggtgtgt ctcttcactg tggcagtaag tgggagggta taaatgcaat
    23401 tgagaaggct atgttgttgc ttcaagatat aaaagagttg gagcataact ggcttatgat
    23461 atataagcat ccactattac cttcacctac aataaattta ggtgtaataa atggtggaac
    23521 agcaggctct actgtgccag ataagtgtgt atttaactta tgtgtacatt tcttgccaaa
    23581 tataatgagt tatgaacaag ttgtaaatga tgtaacaaat gtcataatga caagagctaa
    23641 tggagatttg tggcttaaag ataataaacc aaatataaac atatatcaat cagggttagg
    23701 ctttgagatg gacaaggatt ctgattttgt agtgaatgta cataaaatac tagaagaaac
    23761 tctagggaga agcttagaaa taaaaggttc gacagctggc aatgatgcga gactaatgaa
    23821 aaatttagct gaaataccaa cacttatatt aggaccaggt tcaatagaac aatgtcactc
    23881 aattgatgaa tatgttgaaa ttaaggagta tttagatagt atacttatgt atgcaagtct
    23941 aatattaaac ttataaaagt aggaggaata tataaatgaa aaaagtatta atagtagggg
    24001 aatcttgggt aaaaaatata actcatataa aaggatttga tacatttgtt acaactcatt
    24061 atgaagaagc tgtaaagtgg ttgaaagaag caatagaatc tggtggatat gagacagttc
    24121 atatgcctgc acatgtagca gcagatagtt ttccttataa attagaagag ttaaatgagt
    24181 atgactgtat aatattatct gatataggtt ctaatacgtt cttattatct aatagtactt
    24241 ttatagatta caatagcaat ccagatagac ttgaactaat caaagagtat gtaaataatg
    24301 gtggggcatt aatcatggta ggtggatata tgtcatttac aggaatagat gcaaaagcta
    24361 gatttggaga aactgctatc aaagatgtat taccaataac aatgatagat aaagatgata
    24421 gagttgaaaa accagcagga ataattccag aagttgttga ctctgaacat ccagtattaa
    24481 aaggtatacc aacagaatgg ccgaagtttt taggatataa caaaacagtt gctagagata
    24541 attgtcctgt gttagcaact attggaggag acccatttgt agctgttggt gagtttggga
    24601 aagggaaatc tgctatcttt agttctgatt gtgcacctca ttggggtcca aaagaattta
    24661 ctgattggaa atactataat aaattatggg ttaatatgct tgactggtta acatgttaaa
    24721 aattttataa aacttgaaaa cctcttactt gataaaatga aatttacaag ttaagaggtt
    24781 ttattgcata aaatggctgt aaagtagaaa atatttttaa atcgttaaaa ttagttattt
    24841 tggctaatga atggataagt tattagaaat aaggaggttt atacaattaa tatgagtgat
    24901 ttaaataaaa aatttttaat agaatatata gatgagatac aggaagagtt gagagatata
    24961 tcagataaaa tatggaaaaa tccagaactt cagtataaag aatattatgc ttcaaactta
    25021 caaaaagagt atctaaaaaa acatgatttt agtatagatg aattagaggg tatggataca
    25081 gcatttgtgg ctagttatgg agaaggtgaa ccagttatag cagttttggg agaatatgat
    25141 gcgttagatg gtttgtctca aaaagtatcc attactaaag aacctatttt agatagtggt
    25201 gcgggtcatg gatgtggaca taatttactt ggtacaggtt caataggggc tgtaattgca
    25261 gtaaaggaat taatcaaact aaaaaaattg aaaggaacta taaaatacta tggatgtcca
    25321 gcagaagagg atttgtcagg aaaagtactg atgataaaaa aaggtttttt tgatggaatt
    25381 gattgtgctt ttagttggca tccatttgat ataaatactc caataagaat cccaacactt
    25441 gctaactatt ctgtgaaatt tagatacaat gggattagtg cccatgcagc acaagctcct
    25501 tataatggaa gaagtgcact tgatgcagtg gaacttatga acataggttg taattatttg
    25561 agagagcata tatttgatag ctgtagagta cattatgtaa ctactaatgg tgggaaaatg
    25621 ccaaatatag ttccagattt tgcagaagta tggtattaca taagaggaat taaaatggag
    25681 catgtaagag atgtatttga cagaattgtt gatatagcaa aaggagcatc attaatgact
    25741 ggtactagta tggaatatga cattataagt ggagtatatg attatattcc caatacaata
    25801 ttaaccgata tcctatcaca aaatatgaaa ttgataggag tgcaaaacta taatgaagat
    25861 gattaccatt ttgcagaaaa attagctgaa acggtgtcta tagataaaag aattagtgtt
    25921 tctagtgtgt taagtggaaa taaggatatt actaagatga atttacatgg tgaagttaca
    25981 gatgatactt ttactcataa taactgtata tcattatcat tggatattgg agatgttagt
    26041 tacataattc ctacagcaca atgttcttgt tcggtttggc ctattggtat ttctgctcat
    26101 acatggcagt cttgtgccag tgcaggttct gatatgggat ttaaagctat gttgttagca
    26161 tctaaatcta tagcatgttc aataaatgat gtgatgcttg atgaggtgat tataaataaa
    26221 gcaaaaaaag aattgaagaa tactataggt agttttgaat atataccaat tatttaaaac
    26281 ttaaattgat aatataagca tgaacaactt atataagtat ataatttaat attattttta
    26341 acttaacctt ctaattattt taaatttaag atacaatgat tagaaggaat tttttaagtt
    26401 ttttagaata ctgtatctta tataatcttg ataaaaagtg ttatactata tataatctaa
    26461 ataaaaaata gtacaaaaag gagtatttat gtttggatat gttaaaataa acaaaatgga
    26521 tttaacattt agagaatatg actattacaa ggcttactat tgtggactat gtaaatactt
    26581 aaaaagaaat catggagaaa tctctaggtt ttctttgaat tatgatataa catttttaat
    26641 tgttttatta acagcagtat ataacccaga gtctataagc acagaagaag tatgtatagt
    26701 aaatccattt aagaagaaaa aggtaattac aaatgatatt acagaatatg cagcaagtat
    26761 gaatattctt ttaacgtatt ataaattaga agataattta atggatgata gacgcataaa
    26821 agataaactg gcatattata tatataaaaa taaattaaaa ttagcatatg aaaagtatcc
    26881 tgaaaaagca gagtatataa aacaacaatt aaatgaatta aataaattag aaaaagacaa
    26941 aaatataaat atagatgaag tatctagtat atttggaaat ataatgggtg aagtatttgc
    27001 ctataaaaaa gatgaaaatg agagaaactt aagaatgata ggttttaata taggtaagta
    27061 tatatatcta ttagatgcct atgaagattt agatgaagat tttaagaaag gaagatataa
    27121 tccatttata gagtatattg ataaaaatga tgagttaaaa gaaaaagtaa aaaaaataat
    27181 agtgacatca ttagggtttt tagctagggg aattgataat ctaaatctaa ataaaaatgt
    27241 tggaataata gaaaatataa tttattctgg tgtttattta agatatatga atatattaga
    27301 aagcagaggt ggaaagaatg tacagtaata cttataataa tgaacatttt atgagagcaa
    27361 gagccttcat agaaaataat gaatttaaaa aagcatatga ttttttaaaa actttgactg
    27421 acaaatgtgc agagtggtat tatttaactg gtttttctgc aatgaatata ggatattatg
    27481 aagaaggtga agacttttta aaaagagcaa aatttatgga acctgaaaat agtgaatata
    27541 gtgatgcact tagaagttat acacaatata gaaatgatta tagcaatagg gcagacaatt
    27601 ataatagaag aagacgtaat gatttagatg gatgttgttg ctgttgctgt gatgattgct
    27661 gttgttgcct aggtgacgat tgttgtgaaa attgtgctaa actttggtgt ttagattcat
    27721 gttgtgaatg ttttggtgga gatttaataa cttgttgtta ggatgataaa tatgagtata
    27781 aaagttgctt atggaggagt tttattagca ttaaatgtaa tattgttgac tcttacaaat
    27841 attattcctg taaatacatt gtttattatg gggttagcat cacttttagt atcaattgta
    27901 ataatggaat ggggctttaa gagtggaatt gctttttata taggttctat agctttagga
    27961 tttatagtga tggcaagtaa gtctcaatgg attgtatatt cacttacctt tggaatatat
    28021 ggtattgtaa aatatcttat agaaaaagat aggtctatat atattgagta ttttatgaaa
    28081 ttagtatttg caaatataat gatacttata ttgtattttt tattaagaac aatagtttat
    28141 attccaataa acatatttat cataggttca tttgagatag cctttatagt atatgactat
    28201 gttttcagtt cttttatagg ttattacaat aataggttaa gaaagatgct atttaaaaaa
    28261 taatagttga tttttatatt taattttaat ggaattgtag tttggataag tgtaaatgat
    28321 atatctgaat atacattaaa acataaagct aaatttaata tattcttagt gtaactaata
    28381 aaagctttga tttttagtca aagcttttat ttattaaata taaatattac ttataatata
    28441 agtctttaaa atagatagta taaattaaat atccactata tttacatctg tagataaaga
    28501 ataaataata tcttttcttt ctactattat ttcaacattt ttagaaattt cctcatcaag
    28561 tgatatttga gacaaaagct cctttgttgg atttattgct attggatttc caactctctt
    28621 taacatattt atatctccat tggtatctcc ataggcatac gagtttgata aatctaagtc
    28681 gtactttaca acaaaatcat ttatagcatt attcttactt atagaatccc acattggaat
    28741 aactgtgcct gtaaatatat tattttcaaa gacataatca cttcctagaa aatcggttac
    28801 attatatttt tttgccattt tttcaacaag aaatccaggg ctaccagata taaatataac
    28861 tatatgtcct tgatttagat gccactcaat ccttgaacgc gtgtatttat aaactctatc
    28921 tgcttttaat ttaattactt ggtcacttgt aaagttgata caggttttat ctaatccttt
    28981 taatgaatca acataaaggt cacatatttc taatagataa tcatcataat taccctgtct
    29041 tttatcccaa tccataaaag tatctctagc atgtttatac caattttttt ggtcaattat
    29101 atcgtattta attaatttct taaaatgttc aaccataaga gagtctctat aaagagtacc
    29161 atctatatca aaaaaagctg ctatattttt cataagacca cctcaattaa tcatttcctt
    29221 atattatatt ataaattgta tctaagttgt taaaatatat gtataataat ttatatatta
    29281 aaaaacaagt attttaaagt ttaaaggatg tgactatatg aattttaatt ttgcaaaggc
    29341 tacaaattct agacttatgg gcagtttagg tcttatgata aattggatag atgatgaaaa
    29401 caatcacttt tgtcaatatt ttttattaga tgcagaggga ttaggattag cagattatgt
    29461 gagtttaaaa aatccgacgc aagaagaagc ttatatggaa gaagaaaggt tgatgggagg
    29521 atttggctca gatagagttg aattaacaaa ggatgaatct ttatttttag tatcttattt
    29581 tggtaataag aatctttatt ataataagct actgccagga gataaatgtg aatatattga
    29641 tattataaaa aactataaaa cagatttaac catagaaaaa ttatatgata aaatatgtaa
    29701 aagagttgat gaggaagttg aatttataaa ctatatgact atgagattta tagcatggga
    29761 tagagaaagt ttaaagtact tttctggaag tgacgagatt gcaaatatgc atattaccaa
    29821 tataaatgga acattactta aaaatatagt aagtgataaa ggtcaaggca gatatataag
    29881 tgaagcttta tatgaagaca atgatggata ttatatatgt aaaattgctt tttgtataag
    29941 taaatgttat gaaactggtt ttagaattaa ttctctatta gtaacagata aagaacctat
    30001 gtatgatttt gaggtatttg atgaaatttc taaaagcgaa tttgtaagtg tatacagtgt
    30061 aaattcgcct gaagagtttg caggagtatt ttatagagaa aatccatttc ttttaaaaag
    30121 tgatatgaat gaaggtatat tttttactag atttaatttt aataatgacc atgtaaaaga
    30181 aaatgtatat gtaataaata atgatatgaa agctatatat tacttaatgg gaaataagtt
    30241 ttttattggt acttatgacg aaaatgattg taattatatc aatgaaataa gtcagtctaa
    30301 ttatagtgac tatattaaat ttgaagagaa ttttttcttt gagcaaaatg cattatatga
    30361 ttttgcagaa tcaggttcat tagattttga tgactttttg gaataataaa tttaggcatt
    30421 atttaagcga gattaactga atttaatctc gcttaaattt atttctataa tattggggga
    30481 atattatgag gaatacattt attattgtgg tcaattatta aaattttata cagtttatta
    30541 gaaaaaattt ataattttct ttatgttgtt tgctaatatt agtctaaaat atgagtatca
    30601 taccattctt aactacaaac aaaagaaaga gtttattaaa tgaaaaagtc agataaaatt
    30661 taattttatc tgactttttc tatatttatc ttattagatt atgttaatat ttgttgaccg
    30721 aataagcgta tattcagtca actttctata cctataataa tattggggga atattatgag
    30781 gaatacattt attattatgg tcaattatta atgttttata cagtttgctt aaaaaaatat
    30841 atattacatt tcttcctcat caaattcctc aatattagta gcctgtggta taccttgcat
    30901 agacatatta ctagaaccat aaggagtagg atatatatta ggaggcatag tactaggcat
    30961 aactacaggc ataccttgca ttgtattatg gcatataaca cctggtatca tcataagtac
    31021 attaggaggc atattttgat tacatgagaa gttaggaata cccatagtat tattcatatt
    31081 ataccccata ttactgttca tgttattagg catacctgta ttaccataca tattattatt
    31141 catattgcca t
//
LOCUS       DBGJFK010000042        31023 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.042, whole genome shotgun sequence.
ACCESSION   DBGJFK010000042 DBGJFK010000000
VERSION     DBGJFK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31023
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.042"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(316..2916)
                     /locus_tag="ACOIAP_002244"
     CDS             complement(316..2916)
                     /locus_tag="ACOIAP_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGZ2639127.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLYKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSSKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKVKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARMH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLLNTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISERLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDAIIIEETYVKPRENVLEETPAGNVFIEEPGYYILKVR
                     INIQLPALGYKVVSFESSDKEMVSLNKSNDSFISNDSYKVIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDRAYTEKALGYEKLVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVIIILSKENPLMDVKLCINNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIKDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQIFKKLEFSFAIYMDSKS
                     FDELEIANFTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIINKTVSRELEIISLPENY
                     LISACYPSYYSKDKFVIRLENQSSKRMILDEQIFKNINGKIVNAIEDVEEEQLYEIAP
                     FDVISILLDL"
     gene            complement(2946..4046)
                     /locus_tag="ACOIAP_002245"
     CDS             complement(2946..4046)
                     /locus_tag="ACOIAP_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGZ2639128.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIVVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDESEWEA"
     gene            complement(4062..4382)
                     /locus_tag="ACOIAP_002246"
     CDS             complement(4062..4382)
                     /locus_tag="ACOIAP_002246"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGZ2639129.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            complement(4385..4846)
                     /locus_tag="ACOIAP_002247"
     CDS             complement(4385..4846)
                     /locus_tag="ACOIAP_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2639130.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHRIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            complement(4846..6810)
                     /locus_tag="ACOIAP_002248"
     CDS             complement(4846..6810)
                     /locus_tag="ACOIAP_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2639131.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIASDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLVRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIEILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKEEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVAADQHRDTNELKNTSTNPCETNTNNVSNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDNECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSGCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKCFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            6976..7830
                     /locus_tag="ACOIAP_002249"
     CDS             6976..7830
                     /locus_tag="ACOIAP_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HGZ2639132.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMVSGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVSRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKENKNKKEWFSILIGIMLIMSG
                     VFMLSIIK"
     gene            complement(8072..8539)
                     /locus_tag="ACOIAP_002250"
     CDS             complement(8072..8539)
                     /locus_tag="ACOIAP_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HGZ2639133.1"
                     /translation="MKTKEEYLKEVRTTAEECFRRGEFFCSEAVLHTINNALGQPLSP
                     EITKLASGFPVGLGKAQCLCGAISGGEMALGLVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRVITKKWDGDNFMSPERKEHCIKITGQVAEWVADKLIEDEKLNIK"
     gene            complement(8643..9575)
                     /locus_tag="ACOIAP_002251"
     CDS             complement(8643..9575)
                     /locus_tag="ACOIAP_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGZ2639134.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGVIGFILY
                     AIYIIKIVLLRKGVKEQLENPLISSTFPTITMATMIFATYVKPLSLELGIMIWSIGVV
                     GHLVLIVLFSKKFLIKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLINGHLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIHLSKSETTSKAK"
     gene            complement(9744..10688)
                     /locus_tag="ACOIAP_002252"
     CDS             complement(9744..10688)
                     /locus_tag="ACOIAP_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HGZ2639135.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMICDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELARKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRGDAKISIRDMKTIKVDKNKQISIFD"
     gene            complement(11328..12002)
                     /locus_tag="ACOIAP_002253"
     CDS             complement(11328..12002)
                     /locus_tag="ACOIAP_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2639136.1"
                     /translation="MNDELKTILYSKGVDIVRFVDISEFPTSQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTGSDEFLEKEEKVEGLADWISKYIQSKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RHPLIDSKCLDCNICVENCPAKAIHGNEWTLPGERESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            complement(12062..12808)
                     /locus_tag="ACOIAP_002254"
     CDS             complement(12062..12808)
                     /locus_tag="ACOIAP_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HGZ2639137.1"
                     /translation="MKIENLSINDIKRGYIFNDDLNCYSCIKCTKIYEIGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQMINSDSKYNTLTENQKQLFQLFISDLPDKEIAKKVG
                     VSTSTIRHQKFMFREKAKQAKLYLALYESVFEDKSNKGSTIISIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKQYSEKEVNQILES
                     IYGDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            complement(13286..13972)
                     /locus_tag="ACOIAP_002255"
     CDS             complement(13286..13972)
                     /locus_tag="ACOIAP_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2639138.1"
                     /translation="MAILELINVNYKYEGSSKFVLKDVNAEFEIGKMYVIVGKNRAGK
                     STLLSVISGLDDCTSGSIIYKGEDLKNINKNIYRSKYIGSIFKNHNLLNDATVLDNIV
                     LTMLIAGNKAKNKEDIVYDILKKVGIDKEKANCKVKDLSQDDIRRVCIARALSNNPEL
                     IICDDIIENTDDKGEKSLVDIFYKLASEDNKCVIITTTFDRIALYADELWGITNGNLM
                     FVKSLEKLKY"
     gene            complement(13983..15341)
                     /locus_tag="ACOIAP_002256"
     CDS             complement(13983..15341)
                     /locus_tag="ACOIAP_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2639139.1"
                     /translation="MYILNNAIKNLIRNKVHSLFSIVIILLMVLSIAISSIINLNMSI
                     ITQKYEKKLESEVSIKIDEKKVVQNDLTESLIGYDPLNLEDYLNFSKSKYVKKMSLTG
                     NLALYVDNKKYAPSNDKKLDYNDITTNCIVMGFTDKNKSLKYYNLNISKGRVFQKDNE
                     CIVSEDFLKAGNFKVGDTISLLNDYNTNVKLNLNIVGVYKTKDSNKLESVQDVSIYNN
                     ILTSYNTLVTFEKRVRPESKMIYTSASFLLRDSNSRKAFEKELRNKGLSDIYKVTIDE
                     LLYHKLMAPIERLSGVVFTYTLGILVLGSILLVISSAISIKKIKYDICVLRLIGMSKF
                     KIIRSFIYESIMIILISTVLGLGIASISEKSISNYVFEYQYKYNITYNDFLFNKGSYK
                     DVNTNDINTEQEMKNLKDKSTLNFILKIIFISMILILLTSTVSIYNAIMCKPIQIIYD
                     RN"
     gene            complement(15403..16449)
                     /locus_tag="ACOIAP_002257"
     CDS             complement(15403..16449)
                     /locus_tag="ACOIAP_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2639140.1"
                     /translation="MQGLKDKKTIALILYSVIVFIIFTVGLKYIINISDIDKNLISRD
                     TTLSKSEIPLNNSYVLDKGLMTNYNLILKNNFNVVIILFFAFIVTSNFILLLILNRLD
                     FKERIEILNNINNIEDENEILSIDPIMSRVYKDLKNKFDSHIEDYKRLNSYLSHEQKN
                     AISILRTSLELDGNKELLNVLDKVSNSVEDVLAISYIKNNEDMYEVDIALICAQVCDN
                     YSKVYSNLKFDFDEDENMSIFGREKWIYRGVSNLLDNAIKYGEGKEIYINVKNQKGSV
                     IVSVKDNGIGMNQHHIDKIFYDRYRINELNKDGYGIGLSLVKHVCNLCNGFIWVESEE
                     NKGSTFYLVFKEYK"
     gene            complement(16437..17108)
                     /locus_tag="ACOIAP_002258"
     CDS             complement(16437..17108)
                     /locus_tag="ACOIAP_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639141.1"
                     /translation="MRVLIIEDNKELSYNIKSGLENAGFVVDIANCGLDGEEKAFVND
                     YDAILLDLNLPDKDGIEILEFFRSNNLNTPVIIVTARDGVNELAKGLDLGADDYIVKP
                     FQIIELRARIQAVIRRFYGRTNPNIESGPITINPSSRKVYVYNEEVTLGTKEFDIVEY
                     LASRYPDIVSGIDISEHVYDEYFDPLSSVLRVHIARLKKKLREVAGKEIIITTRGIGY
                     SICKD"
     gene            complement(17495..18379)
                     /locus_tag="ACOIAP_002259"
     CDS             complement(17495..18379)
                     /locus_tag="ACOIAP_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGZ2639142.1"
                     /translation="MRYDIAIIGSGPAGLAAAINAKIRNKNIILFGTEDISQKLIKAP
                     SVENYLGISNISGLELKEKFKNHIDDMGIKITQNRINNVYSMGEYFTLVSGNHVYEAT
                     TVVLATGIEYGKMIKGEDAYLGKGVGYCATCDAMLYRNKKVAIIGYNYEAEEEANFLS
                     EIASNVYYIPMYKLENKINSGINVIDDKPLEIKGGKLVNKLVLRKSELDIDGVFIIKD
                     SISPKYMVPGLEVEGSHIKSDKNMNTNIEGLYVAGDCAGKPYQYLKSAGQGQTAVSSA
                     ISYLDKQKIKEFMLVDAH"
     gene            complement(18545..18862)
                     /gene="trxA"
                     /locus_tag="ACOIAP_002260"
     CDS             complement(18545..18862)
                     /gene="trxA"
                     /locus_tag="ACOIAP_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGZ2639143.1"
                     /translation="MIKIINHNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     DEMAEKAKFLKVDIDQSIELAQKFEVSTVPTMMIFKDGKPVDRLIGFMPKDNLKNKVE
                     SYM"
     gene            19114..19866
                     /locus_tag="ACOIAP_002261"
     CDS             19114..19866
                     /locus_tag="ACOIAP_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HGZ2639144.1"
                     /translation="MNDIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYVPISPNELLKNKKEEFNNSMDKLKNNLQILNKG
                     KNIEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKNLEGLDNIHIHGGNKTTLENKMLYKGIILIVDNNEILTGNLSEGNEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQD"
     gene            19853..20734
                     /locus_tag="ACOIAP_002262"
     CDS             19853..20734
                     /locus_tag="ACOIAP_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HGZ2639145.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTNASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLDSNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNYRKELAQMIGVHEDRLLEYPIMKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVNQNILDKTSFIGEEGNFINRPGKVYVNIAKENNEITS
                     VKIGGSAYTVLSGEIIY"
     gene            complement(20961..22316)
                     /locus_tag="ACOIAP_002263"
     CDS             complement(20961..22316)
                     /locus_tag="ACOIAP_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HGZ2639146.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYSAKFLIYIFLTTAV
                     IHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDNQEELDTAFSVQYSFVNIGSFI
                     GTTAVGILYAKTFAKNGVLGFSQCFFIAAVLCVIGAIWFTYGWRFLGNAGKRPFKEGV
                     VAEKVEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVDMTIG
                     GFDIPLAWFDSLNALVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFTRGVGAPETAKASIMWIIMFGILLSFGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGQGYGYIYAFTLKFEMIKVYTIIPVILFVAAILLFLFDKTLNRLVEDD
                     K"
     gene            complement(24178..24681)
                     /locus_tag="ACOIAP_002264"
     CDS             complement(24178..24681)
                     /locus_tag="ACOIAP_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HGZ2639147.1"
                     /translation="MFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLNPIYS
                     NNTIIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRGGK
                     CEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVSSY
                     ISSHIPQ"
     gene            complement(24898..26307)
                     /locus_tag="ACOIAP_002265"
     CDS             complement(24898..26307)
                     /locus_tag="ACOIAP_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA-like domain-containing protein"
                     /protein_id="HGZ2639148.1"
                     /translation="MENYFDKQAKELYDKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMLREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKSELPWNLYL
                     NRMMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDISGSISDEEFKQAI
                     KEVLSIVKNYNHEIIIIECDNEIRRVYKVKTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVETNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(26311..27441)
                     /locus_tag="ACOIAP_002266"
     CDS             complement(26311..27441)
                     /locus_tag="ACOIAP_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639149.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LVAIDGNLLKEGEIGGLPTIESYVGVNSSGYKTEKKTTVYAVHNKLREIDEEISKGKI
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKENNNSIPRAVFLNVIKGNVGKVIAEEFISFIESDSKPLISYEEV
                     FLGESIDESIVERVKKESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIKFLKMY
                     PVDLMIGIMKDIRNSYTEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(27453..28256)
                     /locus_tag="ACOIAP_002267"
     CDS             complement(27453..28256)
                     /locus_tag="ACOIAP_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639150.1"
                     /translation="MEKSRVIEMIKNNPNIISTIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEEMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYVKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYSAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYIVKKISKDELEEVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRHSENIPIDKIMFIYKYGSKTAKKIAVDEKLKIV"
     gene            complement(28670..30850)
                     /locus_tag="ACOIAP_002268"
     CDS             complement(28670..30850)
                     /locus_tag="ACOIAP_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C1"
                     /protein_id="HGZ2639151.1"
                     /translation="MKKIKKKRIALLLATITTLTFNQKFLVHAYENNYNSEEKLWLPD
                     FTDNDRAKQLEISKLTEKVNLNSIALERIKNINSKQIIENVSPAKLGDEIVKQGDTSN
                     FSLEDNSENIKLPSNVDNSQTKYFPNIGSQGSLASCASYATAYYTMTYMTALVNDWSV
                     KDVSGKNIDSKIFSPKWSYNFINDGKDAGAFAYQNYNVFKTHGCATLADFPYVGLGRD
                     PKNYREWAKDENIWRNATKYQVDEILRVNFNKNNKPNSFITSNKDSNLDDAKRLLLNG
                     YILNFYTWFSDANYKQISNDPSTKDDDSYVNQKAIYQINNQGAHEMTIVGYNDNIWID
                     INSNGKVDDGEKGAFKIANSHGPDYANNGFVWMAYDALNKKSSVLDFTNSNARQGAFL
                     NNEAEYVVISKKETPSKLVRFTMQHDNRKQLQVSLVYEKNGNKQTVVYSPLLSYSGGD
                     FPLDGVNNGSEITFVIDLAHLEKELNVSLSSADKIYLQIKDNLKDDKVAIIKSIILVD
                     NKGHKLSPELISKNVEINGDSKMFDLGQIDNSSELYLQSPEISTDKTLSNNGKFNINV
                     SVPPNNSATKLELFENNVPIETKDLVRSSELQNINFDMSDKKEGFYTYFAVLEDGNGK
                     CLKSEEVNIIVDSIIPPSIKISPNPNKVDVEVIVPAMNNAKTLNVYMDGQKIVNEELS
                     VRNPNEVKKSFVLYSLIVGTHTFWAEVEDENATISSQKVSITID"
BASE COUNT        10481 a         5099 c         3129 g        12314 t
ORIGIN      
        1 ttttatgtaa ttaatatatc agttttataa atacataaca attggtaact tttttgtaac
       61 tacatcaact ctattgatat acaatttcta actcatttta ttaaaatttt attgatttta
      121 aattatatat aaaatcactc taatataata attctttatt taaattgttt atcctgttaa
      181 actaattatt ctacttctat aaattctata ttaaataata aatccataca ttaacattta
      241 cccaaattta tccaaattaa aaagtctggc agattaatat ctgtcagact ttaaacaata
      301 aacttacgtt tacacttata aatccaataa tattgaaata acatcaaaag gtgctatttc
      361 atataattgt tcttcttcta catcttctat tgcatttaca attttcccat ttatgttttt
      421 aaatatttgc tcatctaata tcattctctt actactttgg ttttccaatc ttattacaaa
      481 tttatcttta ctataatagg aaggataaca tgctgatata agatagtttt ctggtaaaga
      541 tattatttct aattctctac ttacagtttt attgatgatt gatttttgaa tcttattgtc
      601 tatacgatat aaaaagaaat tataatcctg taattgatag tttacacatt cccttagata
      661 attgtgggta aaattcgcaa tttccaattc atcaaatgat ttagaatcca tatatattgc
      721 aaatgaaaat tctaatttct taaatatttg agctttatct gttttaattc ttatatgacc
      781 ttttttagtt gtatcaccag aagcacgtcc tggtctatat aataaatcag gctttcctag
      841 ttcatctgta gtagcaagca aggtcaatgc aatttcatct ttaatatgtt gatactcttt
      901 tattcctcta gtaaatacag tacaacttct attttggttt gtcagcgtaa tattactttc
      961 caaaggttct aaatctatag gcatctcact gtaaatatct tcccagttgt ctaaaactcc
     1021 attttctctt gttatatatc caaatggcaa tgatgctata tttttattat cttttatatc
     1081 agtttttata tgaacacgca atctatgatt atatatcgtg ttattaatac aaagttttac
     1141 atccatcaat ggattttctt tggataatat aataattact tttacattta atttaccatt
     1201 aagatatttg ttttttctat cttctaatgt aagcggtagt aaagtagtac ctttaactac
     1261 caacttttca tatcctaaag ctttttctgt atacgctcta tcaaatgaaa gtttgatatc
     1321 ctcatcattt tttaatggag aaaaatcata ggtgtcacct gcattaccac tatcttttaa
     1381 tgttaaaaag tttgatatgt aagttccatc tttaagttgt aaatttaaac ttccatcttc
     1441 atagattacc ttataactat cattagatat aaaagaatca ttagatttat taagtgatac
     1501 catttcttta tcacttgatt caaagctaac aactttataa ccaagtgcag gaagctgtat
     1561 atttattctt acttttaata tataatatcc tggttcttca ataaatacat tgccagcagg
     1621 tgtttcttct aatacatttt ctcttggttt tacataagtt tcttcaatta taatagcatc
     1681 taaattatct ttaaaataaa tatttttact atcacttaca acttgtatct ctttatatcc
     1741 attaaagcgc ttggcttctg tattaaatac taaaatgtca tttttagata atttaagcct
     1801 ttctgaaatt tttttgacaa tagtattttc aatactgtca catatttcat ttgcttctct
     1861 tatacggtga agaatatcat ctgttacagt atcagttaca catccagcta aactatcgtg
     1921 tgcttgccct tccaaaagtt ttttccatgt atttaaaagt aactgattgc ttatttcaat
     1981 tttactcttt ttagcaatta ctagtaatgg ttctattctt ttaatcagct tgttttctag
     2041 tttatcacat gctaatttta tatccattct actagaacca attgatttat gcattcttgc
     2101 caatacaggc tctctaaatt cacctctata gctttctagc gattctatgg attttatata
     2161 ttttaaaaac tcttgatatg aactcgttat atatgaatac tttccgatat cattaatcgc
     2221 tttaacttta tttttgaaat cacctattat atttagctgg tcatttccag aaggtattaa
     2281 cacctcatct acatcagtat atgatttaat aaaatcaata gctgggtcta agcgtccatt
     2341 aacatacttt gatgaaggtt ctaaaagcat accagttcca tatccatgtg gcatatttac
     2401 tgcatatata taactttctc catttaagct tttccactta aaatatggtg attgaacctg
     2461 tttaccaaga tgtatacctc tccaaaagaa tatattatca agacctacat gctttaatag
     2521 tataggcatc tgtgcattaa atccaaatgt atctggcaaa tatccaattt tcatatactt
     2581 accatacttt ttactttcaa aaattccaat cattaagttt cttaaaatag actctcctct
     2641 agcaaagaat gcatcagttt gagtaaacca tggtccaata tgtagtctat cttcttttat
     2701 caacttttta atgatttcta ttttttcttt gtataattgt acataatcat ccaaaataga
     2761 aagttgtcca tcaagtacaa aacttacatc tgggttacgt tctaattcat caattacatc
     2821 tgtaaatagt tgttcactaa gtaccaatgc atctccagaa gtaaaatacc attctctatc
     2881 ccagtgtgta tgattaacaa tatgtgcttt tatcatttat tctcctctgt tctttatctt
     2941 taattttaag cttcccactc tgattcatca aaatcatcat cttcaaattc atcatcttca
     3001 atcactggat ttccacgcaa tactataact aacccagcta caattactgt tccaactact
     3061 attgataaca catacattgg ccaattctct actgtaaacc atccataaaa tccactaatt
     3121 ggagttgcat ttactgaacc taaaccaact gccatagctg aagcaattgc agttccaatt
     3181 acgcatgaag gtattacttt taatggagat tctaccgcaa aaggaattgc accttcactt
     3241 actccaatta accccattat aagagatgac ttcccagctt cacgtaactg tttattatat
     3301 ttttgttttg ctagtatagt agcaagtccc aatcctagtg gtggtataac tattcctacc
     3361 attgcagcag tattaggtgc ataaattcca cttgttaata atgcaagtga tgttgtcaaa
     3421 gctgctttat taactggtcc acctaggtca actgccatca tagcccctat aatagccgcc
     3481 attaatatct gatttgtacc agataatcca tttaaccaat tttctaatcc agtatttaat
     3541 gtggcaaaag gtatacctat cacatagtta attaatacaa cagtgattaa tgttccaaat
     3601 actggtacta taaatattgg tactattgaa gctgctgatt ttggtaattt gacatgattt
     3661 ttaataaata aacatgtata tcctgctata agaccaactg ctaaagctcc taaaaatcct
     3721 gcacctatat ctttagcaat cataccccca acaagacctg gtacaatagc taatttatca
     3781 gctatagaaa atcctataaa tgcagcaatt acaggaaaca ttaatcctaa tgcagtacct
     3841 ccaaatccat ctaaatcatg caataatcta acaatactac tagcactttc tgcatattta
     3901 gcatcccata tatctggtat attatagaaa gaaccaccta cacgagatat tgccattatc
     3961 atagcacctg caattactag tggaatcata tatgagattc cagttaagac atgctttttt
     4021 aactcagaga ctatcttttt caacattaca tttccctcca tttatttagt gtcaattaac
     4081 tttaatgcat catttattac tttctctgca tcctttatag gcgcattaac tggtacttct
     4141 agtatttctt ttccctcaaa acgttcagca tttctgactt tagtgtctac tgcaaatatt
     4201 actacttctg caatttgtgc atcctttgta gttagctcat tatcgattcc tgtagctcct
     4261 tgtgtttcaa cttttataag gtgacccatc ttttttgaag ctttctttaa tgcttgagct
     4321 gccatatatg tatgtgcaac tcctgttgca catgctgtaa ctgctataat ttttcttttc
     4381 atctctacat ctctccttct tcactaaata tattgattat ttcttgttct gaattggcta
     4441 attttagtgc atctacattg tcatcatcca taagtttagt tgccaattta gataatagta
     4501 caagatgatt gctatcctta tcaatattgc ttatagccaa taagaaaatg ctatctactg
     4561 gtttttcatc taaagcatcc cactcaattc tatgcttagt ctttgcaaat attatagaag
     4621 atttcttgac agcattactt tttccatgag gaatagcaat accattacca atacctgtag
     4681 ttgaatgctc ctctctttcc aaaacagact taacatattc ttcttcattg tccacaatcc
     4741 cattttcaac aaatatacta cttaattttt ttattgtttc ttcctttgta tttgtatcaa
     4801 gattaaaaac aatttgttct tttttcaata catctgatat tttcactata tactctcctc
     4861 cactagcaaa tcgtacactt cctttgtaga agttgcactt aatatgtcat ttatattttt
     4921 tttattgtca atgaagtcat aaaaaacttc atatatttca tcaagctcta ggtttttgtc
     4981 attttctaac gaaataaaga aaataacttc taccttttca tttccccatg taataggatt
     5041 ttttaacgtt gcaacagata tattagattt tttaatataa ctaggattag catgaggtgt
     5101 agctattgat tggaaagatg tgtaggataa attttctctc tcaattgcac ttttagctat
     5161 accttctttt gcaaaacatt tttttattag gttatctgtt atatacttaa ttgcatcttc
     5221 ataatttgag gcttcaatat ttaacaatat attttcttca aagattaaat ttctgaaaga
     5281 tttatacttc ttagaagtac aacctgaaac attttgtata tttctttcca aggttcttat
     5341 atcactttca tttaaaatag ggctaactac tatcgttgga atagtttcta gctctaaata
     5401 aatagtactt attactaagt ctgcatcaat tttactagat actaattctt gtacagaaag
     5461 cactttttca atctttatca ttggaaagta tttttttatt cttgcagaca ataacctaga
     5521 tgaacctagc cctgtactac atactagaat tactctaata ttttgtggaa gttctttcat
     5581 tctttctcta aaagcttcaa aatgtaatgc tatataagca cattcattat catttatcct
     5641 aatatcatat ataaattcaa ttactttctt taaatctaaa gcttgctcaa atgataaaga
     5701 aaagttttgt ttgattgtat ttacatatgg atttttaata ctaagtccat atttcaatct
     5761 atttattgat gaatgtacat gtgaagtcaa tccatcaatt aaatccttat cataagctgt
     5821 ctcatacaat gtatttttta taatttcccg aagatttgat acattatttg tatttgtttc
     5881 acaaggatta gttgaagtat tttttaattc attagtatct ctatgttggt cagctgctac
     5941 taaatgtaaa tttatatatc caatttcaga ttttggtaat aatattgaaa atttttcttc
     6001 taattgtttt gctaaataat tggtatttga catttgatta ttttctatat taccaatata
     6061 caaactttct tctatatatt cttcttttct aattctctct acagctattg ccaaatgaat
     6121 aactaacgac tgaaattcat aatcagagaa ctcaaatttt ctttctctgc tgaaattcct
     6181 aagaatttca ataattattg ataaatcatc ttcagaaaaa ataccattta catctgcctg
     6241 tatcttctca aatgcttgat aaaagctttc ttgctcttgc ttaatatacc agtttctact
     6301 ccaaaattta tgtataaact tagcagtaag ttgtctttta tctctttcac ttatatttaa
     6361 ctttattcct ttactaggtt tcttatatat ggaaatccct tcatttttta acaatttttc
     6421 gacttcggct aaatcccttt caatagttcc acgacttata tataattcgt cagaaagttg
     6481 ttgtatagtg atatagtcat tactcttcaa aagtactgaa tatatataga taactctctc
     6541 ctctctggtt gtaggaattt gacttccttt attatctagg taaggaagta ttttttttaa
     6601 atctccatca atataaacac ctatcttagg ttttcttact aaagaaagac ctatcttttt
     6661 aagcactgct tctacttctt taagagattt tgaaactgtt ttttctgaaa cgtctaaatc
     6721 acttgctatt gcttttacag ttgtatgacc ttcttttaat aaaaacttta ttattttaat
     6781 ttcacgattt tgaatcatat cagttaacat tttcaatttt actccttccc tttgtcttta
     6841 ttctaatgga aaatgttttt ctaaaaaact actaatattt cctgattaaa tacggtaatt
     6901 tttatgtatt gaatacttta attttagatg ataaattaaa aactgtctaa atttaatatg
     6961 aaaggaaata gtttaatgct gacaataatt attgctttac ttcctgtaat gggatgggga
     7021 ttgatgccca tagttgcaaa tctaaagaaa agttctcctc atgaacaact tttaggtaca
     7081 tccataagtg cgtttatatt ttccactata ataactctag ttatacatcc tgaaattaca
     7141 tttttttcat tttgtataag tatggtttct ggcatattct ggagtttagg acaattaatg
     7201 caatttaaag caattcaaat tgctagtgta tctaaagtaa tgccgatttc aaatggttca
     7261 caattaactt ttacgacatt actagctgta atcttattta atgaatggac aagttctaaa
     7321 atgttactga ttggttcttt atcaatatta tgtataatac ttggtatact tctcacaaat
     7381 tatcaaacta aaaaatctac agataaaaat atgttaaaat gtgttggagt tgtattatta
     7441 tcatctctat ttttatcatt atatgttgta actaatcaaa tatttttaat tgaaggatat
     7501 agaattatat tacctcaatc tgttggtatg ctgataactt catctattat tgtcaaatat
     7561 ttttctaaag agattgtatc cagggaaaac gtcttattca atttaattac tggaatatta
     7621 tggtcaatag caaatttagg tatgttcata acgactaata cattgggagt tacaataagc
     7681 ttttctatct ctcagagttg tgtgatagta gccactttag gagggattat attttttaag
     7741 gaaaataaga acaaaaagga atggttttct attcttattg gtataatgct aatcatgtct
     7801 ggtgtcttta tgttgagtat tataaaatag gtatttattt acacaaatca tatacatttt
     7861 tatacatata aattaactgt ttctatttat taataaattt acctatatac ttaaaataat
     7921 agcatatgta tttatgaaat taaactatac tctaaatgta agtatatttc attaaataca
     7981 tatgctataa atttttctgt caataagaga gtacaaaaca tcttatattg taaataaatt
     8041 taactttata aatttaccaa ctaatattgt attatttaat attaagtttt tcatcttcta
     8101 taagcttatc tgcaacccac tctgcaactt gacctgttat tttaatacag tgttcttttc
     8161 tttcgggaga cataaagtta tcaccatccc acttctttgt aataactcta caacatgtcg
     8221 caccatattc ttttttaata taatcatgca accctttagc atgttcaaac atctttggat
     8281 tcatagcttc accatgaact cttccatata ctaaacctaa cgccatctca cctccagata
     8341 ttgctccaca aagacattgt gcttttccaa gtcctactgg aaatcctgat gctaacttag
     8401 ttatctctgg acttaatggt tgtcctaaag cattatttat tgtgtgaaga actgcttcag
     8461 agcaaaaaaa ctctcctctt ctaaagcatt cttctgcagt tgttctaact tcttttagat
     8521 attcttcttt tgttttcatt ttttccctcc aataaaatta agctaaatta agtttctatg
     8581 gtttgtctta tgttcgtata tttatataaa tattcctacc aaagacacat atttaataat
     8641 tcttatttag ctttagatgt agtttcagat ttactaagat gtataataaa taaaactaaa
     8701 acatataaaa taatcactgt agcaattatc tcttctaatt tagaagcata tgaaatccaa
     8761 cttataaaat gacctgattt agttaaatga ccatttatta gtttcatccc cattgcactt
     8821 attgccatag ggaatgtaaa tgcagcaaaa ctcggataaa aaggcaatct taataatttt
     8881 ggtaaatatc ccaagactat aatataaaac acaattgata atataaataa caagtataat
     8941 actacattat ttttatctga aaaagaatta atatatccag acaataatag tgaccctggt
     9001 gcagctaata tagctatact tggtaaagat ggttcaggca tttccttgat tatccatact
     9061 ctcttcaaaa ttactggtat aagaactata taagatacaa atcctatcca aaaagcaatt
     9121 ttgccaatca aaagttgatt aaatgctgga gctgtaacac tagctgcaac tatcccaaca
     9181 tagactatat accaagatgg aaatactgtt tttattgaga atttaattag gaatttttta
     9241 ctaaatagga ctattaacac aagatgaccc acaactccta tgctccaaat cataatacct
     9301 aattctaaag ataatggttt tacatatgtg gcaaatatca ttgttgccat tgttatagtt
     9361 ggaaatgtac ttgatattaa gggattttct aattgctctt taacaccctt tctaagtaat
     9421 actattttga ttatataaat tgcatataaa ataaatccta taactccaat tacattacgt
     9481 aatgattcac tataagattg taataagtta cctaaagtaa atattgacaa aatcaaactt
     9541 gcaataggta taggatattt ttttaatagg ttcaaattat gcctcctttg ttactaaatt
     9601 atttatgttt taattatatc aaaaagatgg tcaaattgac atattatgac catctttctt
     9661 atatagaaaa tatctatcaa atttaatttt attattataa ttatctatat tcttaatata
     9721 ttaagttaat tagtatattt attttaatca aatatactaa tttgtttatt cttatctact
     9781 ttaatagtct tcatatctct aatgcttatt tttgcatcac ctcttaaagt atctatgagt
     9841 aatttattat cttctttata aagcctacag ttttcttcta cttttgcata attaaagtta
     9901 gcataacaat acagacaata atgtctgcaa gtattgtatt gccctatatc gacacttttt
     9961 acacatccac aaatatctct ttgtgtacta tcttttttta cctctacttc acatcctata
    10021 atttttgata ttaatctatc atcaatacac ttactttttc caatcccaaa tttacttaaa
    10081 ttatattctt cagagcacat ttcaagtgtt atcccatgct tatgagcaat cttagaaatc
    10141 tcttttgata atgtttctat ttctgtaatt tctattggct ttatatgtaa tgctttagta
    10201 ttaaattttg ttttcttata taaatcgata aaacttatta tacatttttc tgtaaatcca
    10261 tcaagctgat tacataaact cgcaaatgct ttgatatgat aatctactgt gtacttttca
    10321 cttaaaaaaa tcgggtcata ccttaaaatt actctttctt tgcctatttt tctagccaat
    10381 tccttaaatg aatctattac ctttctttta tctaaaatgc aggtctctac ttctttgcca
    10441 tatgatgtta tagtatagtg gaaataatat ttatagtctt ttaatttatt taaatcacat
    10501 atcattggag tcacatcctt tgtccaaaat acaaaacaat caacagtatg tggatttaac
    10561 tctatcttac taacttgctt tggattcatt ggattaatta cataaacaaa accttcttta
    10621 agtctgttaa aaaaccactt actatagaaa gcaggtatat cagttcttct actcacactt
    10681 actatcattt ttaacctcca tagtaatata attatgctct aatatatttt taatataatt
    10741 atagctctaa atacttaatt taatcaaaac atttaagata attccagtat gatttactga
    10801 ttcatttcta gcatttaaaa tatccttaat aagtttacaa ttctttaaaa ataaatatat
    10861 attattccta aacttctaaa actaatttta taatgaaact aaaaaaggtg ctattttcaa
    10921 gcaccctaat ccaatctgga gttttagttt caatttccat gattaattcc tcctttttaa
    10981 atctaaattc ttctcacaga aacaattttg aactataact gaagtgcctt ttactatctt
    11041 tgggaatttt gagaatagca ctttcatttt cacaatatta ttataatttt attatatttt
    11101 tttataatct cattatattt tcactattac taaattactc ttaatttttt aatataaatt
    11161 ttgtacaatg attaaaatag ttaagcttta tatcaatata atctaatccc aataaaaaaa
    11221 acactcattt ctgagtgttc tatacaagtt tttattttga gacatcttat ataatcttat
    11281 attttaaaaa gtttataata tccaatttaa tatcttcttt agtaaagtta tttttgattt
    11341 gcatatctta gtgaccatgg acaactcatc atgcacctca atacacaaaa acactttgaa
    11401 acatcaataa tagactccct ttctcctggc aaggtccact cgtttccatg tatagctttt
    11461 gcaggacagt tttctacaca aatattgcaa tctagacatt ttgaatcaat caaaggatgt
    11521 ctttcaacag aaattggagc gtctgtaagt actgtacaca tactaaaagc acatccatat
    11581 tcctctgtta caaacaaatt atttttcccc ataaatccaa taccactaat atttgctatt
    11641 gtcttatgtg gcaaaggact aatccctgat tgcatttctg gattaatata agctttttca
    11701 aaatatccat gttctagatt atttttctct gattgagaat aagctctata tcctttactt
    11761 tgaatatatt ttgaaatcca atcagctaac ccttctactt tctcctcttt ttctaagaac
    11821 tcatcactac ctgtaggtaa gttattgtat atatctgtaa taaatttttt tgataaccct
    11881 atacaaaata aaattgcttt agagaaaccc tgtgtttgac ttgttggaaa ttcagatata
    11941 tcaacaaaac gaacaatatc tacaccttta ctgtataaaa tagtctttaa ttcatcattc
    12001 atgtttgact ccttctatag gtaaaaacaa ccttatatat taataaaatt aactattcta
    12061 attatgttaa ccaatacttt gtacattctt tatttctact cataaaacca tactcaatta
    12121 aatatcttct aattgttgca aaatcaccat atatagattc taaaatctga ttaacttcct
    12181 tttccgaata ttgcttccca cgttcaaatt gttccaaaat cttagataga attacgacct
    12241 ttttcttttc ttttgaagaa aatactttta attttaaagg attcatactt tcaaatgatg
    12301 tatctaaaat gtgttttctc tcttcttcag ttactacata tctttcatct accattcgag
    12361 catgttcatg aattgatatt atggtgctac ctttattaga tttatcttca aacacagatt
    12421 catatagtgc caaatataac ttagcttgtt ttgctttttc tctgaacata aatttttgat
    12481 gacgtatagt agatgtagac actccaacct tttttgcgat ttccttatca ggtaaatcac
    12541 taataaacaa ttgaaataat tgtttttgat tctcagttaa tgtgttgtac tttgaatcac
    12601 tattaatcat ttgctctaag taatcactat gttctaattc catatgaagt tcaatagctt
    12661 ttgaagcttc aaagaatcta ttacctattt tatatatttc tcctatttca tatatttttg
    12721 tacatttaat acaactataa caattcaaat catcattaaa tatataacct cgtttaatat
    12781 cattaataga aagattttca attttcatat tactgtctcc atttcatatt ttttcatttt
    12841 tataaatata tcatatcaaa gtttattaat ataatcaaca tttttaattt ttgtttataa
    12901 aatataatta tttattaatt taaaatcaca atatatttcc cacctttaat atcattacct
    12961 acattattat gtattcatat tgtgatttga atgattagtt attgtaactg gagtaataag
    13021 tgatatcccc tttaattcaa tcttagagtg gtcaattttc aaaattggag ttccttcttt
    13081 ttaaatttac atcagctaaa tcaaaggcta tcattagttc taattaatat ttaacatttt
    13141 atgtaaaatt tataaaaaaa tgtatataaa ttaagataag tgactatact aaaaatatga
    13201 tacggacaaa caataagttc aacctatctc ccccaaaata aaatgagcta cagtttcccc
    13261 caactgtagc tcattttcat gtaatttaat attttaattt ttctagactt tttacaaaca
    13321 tcaaattacc attagttatt ccccataatt catcagcata taaagcaatt ctatcaaaag
    13381 ttgtagttat tatcacacat ttattatctt cagatgctag tttataaaat atatctacca
    13441 aactcttttc acctttatca tcagtatttt ctataatatc atcacaaatt attaattcag
    13501 gattattaga taatgctcta gcaatacaga ctctcctaat atcatcttga gacaaatctt
    13561 tcactttaca atttgctttt tctttatcaa ttcctacttt ttttagaata tcatatacaa
    13621 tatcctcttt attctttgct ttatttccag caatcagcat agttagaaca atattatcta
    13681 acacagtagc atcatttaat aaattatgat ttttaaatat cgaccctata tacttacttc
    13741 tgtaaatatt tttattaata ttttttaaat cttctccctt atatataata cttccactag
    13801 tgcaatcatc aagacctgat attacagaca ataaagtact ctttcctgct ctattttttc
    13861 ctacaattac atacattttt ccaatttcaa attctgcatt aacatctttt aatacaaact
    13921 tactgctgcc ttcatattta taattaacat taattaattc aagtattgcc aatctatatc
    13981 acctaatttc tatcataaat tatttgtatt ggcttacaca taattgcatt atatatagat
    14041 actgtactag tcaataatat caatatcatt gatataaaaa ttatcttaag tataaaattt
    14101 aaagttgatt tgtcttttaa atttttcatc tcttgttcag tgttgatatc atttgtattg
    14161 acatctttat aactaccttt attaaacaaa aaatcattat atgttatatt atacttatac
    14221 tgatattcaa aaacataatt tgatattgat ttctctgata tacttgcaat tcctaatcca
    14281 agtacagtag atattaagat tatcatgata ctttcataaa taaagcttct aattatctta
    14341 aacttagaca ttccaattag tctcaacaca catatatcat attttatttt ttttattgat
    14401 atggcagaac ttatcaccag caatattgaa cctagcacta atataccaag agtatacgta
    14461 aaaaccacac cagataagcg ttctattggt gccattaatt tatgatataa taactcatct
    14521 atagtaactt tatagatatc acttagacct ttatttctta attctttctc aaaagccttt
    14581 ctactattag aatctctaag taaaaaacta gcacttgtat aaatcatttt actttctggt
    14641 ctaacccttt tttcaaacgt tactaaagta ttatatgagg ttaatatatt gttgtatata
    14701 cttacatctt gaacactttc taatttatta ctatcctttg tcttatatac acctactatg
    14761 tttaaattta acttcacatt agtgttataa tcatttaata aagatattgt atctccaacc
    14821 ttaaaattac cagcctttag aaaatcttca cttactatac attcattatc tttttgaaat
    14881 actcttccct tacttatatt taaattgtaa tacttaagac ttttattttt atctgtaaat
    14941 cccatgacta tgcaatttgt agttatatca ttatagtcaa gttttttatc attactaggt
    15001 gcatattttt tattatcaac atatagtgca aggtttcctg taagtgacat tttctttacg
    15061 tattttgatt ttgaaaagtt taaataatct tctaaattta aagggtcata tccaattaaa
    15121 gattctgtta aatcattttg aacaactttt ttttcatcaa ttttaatact aacctctgac
    15181 tcaagctttt tctcatattt ttgagttata atggacatat ttaaatttat tattgaggaa
    15241 atagctattg ataagaccat taataatatg ataactatac taaatagact atgaacttta
    15301 tttctaatca agtttttaat tgcattattt aaaatataca ctttatatct cctcttatta
    15361 attaaattct atattaaata tttttataat tcttattaac tcttacttgt attctttaaa
    15421 cactaaataa aaagttgaac ctttattttc ttcactttca acccatataa acccattaca
    15481 taaattacat acatgtttta ctaaactaag acctatacca tacccatctt tatttaattc
    15541 atttattcta tatctatcat aaaatatttt atctatatga tgctgattca ttccaattcc
    15601 attatctttt actgatacaa tgacacttcc cttttgattt tttacattta tatatatctc
    15661 tttaccttca ccatatttta ttgcattatc caaaagatta gatacacctc tataaatcca
    15721 tttttctctc ccaaagatac tcatattttc atcttcatca aaatcaaatt tcaaattgct
    15781 atacacttta gaataattat cacatacttg tgcacatatt aaagctatat caacttcata
    15841 catatcctca ttatttttta tataacttat tgcaagtaca tcttctacgc tatttgaaac
    15901 tttatcaaga acatttaata attccttatt tccatcaagt tctaaactcg ttctaagtat
    15961 tgatatagca ttcttttgtt catgtgataa atatgaattt aaccttttat aatcctcaat
    16021 atgagaatcg aatttatttt ttaaatcttt atatactcta gacataatag ggtctatact
    16081 cagtatttca ttctcatctt caatgttatt tatattattt agtatttcta ttctttcttt
    16141 aaaatccaat cgatttaata ttaataaaag tataaagtta gaggttacta taaatgcaaa
    16201 aaatagtatt ataacaacat taaaattatt cttaagtata agattataat tagtcattaa
    16261 tcctttatct aaaacataag aattgtttag aggtatttca ctcttagata aagttgtatc
    16321 tctagaaatt aagttcttat ctatatctga tatatttata atatatttta aacctactgt
    16381 gaaaattata aaaactataa cagaatataa aatcaacgct atagtttttt tgtcttttaa
    16441 tccttgcata tagaatatcc tatccctcta gtagttatta ttatctcttt acctgcaact
    16501 tctcttaatt tcttttttaa tcgagctata tgtaccctta atacagatga taaagggtca
    16561 aaatattcat catagacgtg ttctgatata tctatacctg acacaatatc aggatatctg
    16621 cttgcaaggt attctactat atcaaactct tttgtcccta aagttacttc ttcattatat
    16681 acatatactt ttctagagga tggatttatt gtaattggac ctgattctat attggggttt
    16741 gttctaccat aaaatcttct tataaccgct tgtattctag ctcttaattc tataatttga
    16801 aatggtttta ctatataatc atcagctcct aaatcaagtc cttttgcaag ttcgtttact
    16861 ccatctcttg ctgttacaat tattacaggt gtatttagat tattacttct aaaaaattct
    16921 aatatctcta ttccatcttt atctggcaag tttaaatcta ataatatagc atcatagtca
    16981 tttacaaatg ctttttcttc tccatctaat ccacagttag ctatatctac tacaaaccct
    17041 gcattttcca aacctgactt tatattataa gaaagttcct tattatcctc tattattaat
    17101 actctcatat aatcatctcc taaataaaat atcagtttat ttattatata taatgaatgt
    17161 ttattgaatg ttaactttat tttataagta tttatatttt aaacaaaaca caattttatt
    17221 attattcaaa tgcttgtatt tgtcaaattt aagatgaatt tatctaatca tttagttatt
    17281 atcagcaatt taaaaaggtg aattcatcta atagaaccca cctttttcaa ttaaatcttt
    17341 attttgaaat agcatttctt agtattgagt gtatgtatta aaaaaacaat ccctgtaatc
    17401 tttattaatt ttaaatatat ctttcagtat tgaatccaca atcaataaca acttataatg
    17461 atttattgtg gatataaaaa cttcatagtt ttatctagtg agcgtcaaca agcataaact
    17521 cctttatttt ctgcttatct agataagaaa ttgcactgga tacagctgtt tgaccttgtc
    17581 ctgctgattt taaatattga tatggtttac cagcacaatc tcctgccaca tataaacctt
    17641 caatatttgt gttcatattt ttatctgact ttatatgaga gccttctact tctaatcctg
    17701 gaaccatata ttttggtgat atactatctt ttataatgaa aacaccatct atatctaact
    17761 cactctttct caatactaat ttattgacta gttttccacc ttttatttct aaaggtttat
    17821 catctattac atttatacca ctattgattt tattttctaa tttatacata ggtatatagt
    17881 atacattact tgctatctca cttaaaaaat ttgcctcttc ttctgcttca tagttgtacc
    17941 ctattatagc aactttttta tttcgatata acatagcatc acatgttgca caatacccaa
    18001 ctccttttcc aagatatgcg tcttctccct ttatcatttt tccatattca atacctgtag
    18061 ctaatacaac tgtagttgct tcatatacat gatttccaga aactaatgta aaatattcac
    18121 ccatactata tacattgttt attctgtttt gagttatctt tattcccata tcatctatat
    18181 gatttttaaa tttctcttta agctctaaac cacttatatt actaattcct agataatttt
    18241 ctacagaagg agcttttata agtttttgac ttatatcttc agttccaaat aaaattatgt
    18301 ttttatttct aattttagca tttatagcag ctgcaagccc tgctggacca cttcctatta
    18361 tcgcaatatc gtatctcata atctctccta ttttcaataa cctttccttt tttatctaaa
    18421 taatatatcg aaagtcaatc tcattagcaa ttggatactt atttataacc acacaaactc
    18481 ttatactata taaacaaaaa aactcattat aatgagtttt ttgtttatat atgatttatt
    18541 ttaattacat atatgattca actttgttct ttaaattatc cttaggcata aaacctatta
    18601 atctatctac aggttttcca tctttaaata tcatcatagt tggcactgtg gatacttcaa
    18661 atttttgagc tagttctata ctttggtcta tatctacctt taaaaatttt gctttttcag
    18721 ccatttcatc tcctaaagct tcatatattg gtgataacat cttacaaggt ccacaccaag
    18781 ttgcaaagaa atctaccact actaatccat ctttattttc tacttcgttt ataaattcat
    18841 tatgatttat tatttttatc ataatttaca tctcctttat tattttcttg atattaatat
    18901 actacgacct gtgtaatact tcaattagtc acttttttgt aaccttctat ttttgctggc
    18961 tttaatatta tgataagcat atttataaga ttaaatgttt ctaatatatt ttaatttttt
    19021 cattaatata gttgacattt tttactttag attataaaat caaattaata actacatagg
    19081 tagttactaa acttttatat aaggagttta tctatgaatg atataattaa tgaattacaa
    19141 aatataggat ttactaaata cgaatctcaa atatacatat cattattaaa ggaaagccct
    19201 ttaacaggat atgagataag taaattatca ggtgtaccac aatcaaaagt ctatgaaaat
    19261 ataacaaagc tattaaacaa taatataatt atcaatgttg gaactgaccc tattaaatat
    19321 gtacccataa gtcctaatga attattaaaa aataaaaaag aagaatttaa taattctatg
    19381 gataagttaa agaacaactt acaaatatta aataaaggta aaaatataga atacgtttta
    19441 aacataaagg gagataaaaa tatattaaaa aaagcaatag aaatgataaa aaatgcaaaa
    19501 caagaaatta taatttcttg cccttatgaa gaaattcttg aattaaaaaa agaactccta
    19561 attgcttaca aaaaaaatat taacattgaa atactacttt tagaaaataa aaatctcgaa
    19621 ggtctagata atattcatat ccatggaggt aataaaacta cacttgaaaa taaaatgctt
    19681 tacaaaggaa ttattttgat tgtagataat aatgaaatat tgacaggaaa cttatctgaa
    19741 ggcaacgaag ccatttcaat ttggacaaaa aactctaaca ttttatatat tggagttcaa
    19801 tacataaaac atgaaattta tatttcagaa caaataaaag gaggttataa aaatgaacaa
    19861 gattaagatt aaacaagttg atgcttttac aactatacct tttggtggaa accctgctgg
    19921 tgtagttact aatgcctcta atatttctga tgaaatcaag cagaatgtgg ctaaagaaat
    19981 gaatttatca gaaactgcat ttgtttcaga gtcaaatgtt gcagatttta aggtacaatt
    20041 tttcacacca ggtttagaag ttgatttatg tggtcatgca acaataggta ctttccatgc
    20101 acttttggaa gaaggaaaac ttgattctaa taagagtata ttttatcaag aaacaaaagc
    20161 tggtgtatta tctgtagagc ttaaggaaat aaataatgaa aatatattta tgatggagca
    20221 gaatacacct gaatttgaaa atttagataa ttacagaaaa gaacttgcac aaatgatagg
    20281 tgtacatgaa gatagacttc ttgaatatcc tattatgaag gtaaatactg gactttggtg
    20341 gcttgtgttt ggcttaaaat ctttagatga tttaaaaaat atctctccag atttaaataa
    20401 aatcaaaaaa tttagtggtg ataataatat aattggcata accccatttt gtatagaaac
    20461 tatagataaa aagtgtgact accatttaag atctatcgca ccatatgttg gagttacaga
    20521 agaccctgta tgtggaactg gaaatgcttg tgtatcatct tatatagtaa atcaaaatat
    20581 tttagacaaa actagtttta ttggtgagga aggtaacttt ataaacagac ctggaaaagt
    20641 atatgtaaat atagctaaag aaaataatga gataacttct gtgaaaattg gaggaagtgc
    20701 ttatactgtc ttaagtggtg aaattatata ttaatctcat ccctaataaa aacaaataaa
    20761 aatactagct aactaatgct agtattttta tttgtttatt tttatttaat aataatactc
    20821 taatacatat tataatcaca tatattataa cattatattt agaagtaaaa ttttattttt
    20881 actattaatt agttataaat caatctaata caatataatt acaatagatt aatccataaa
    20941 acacaataat tacttactga ttatttatca tcctcaacaa gtctatttaa tgtcttgtca
    21001 aataagaata ataatatagc tgcaacaaat agtattactg gaattatagt atacacttta
    21061 atcatctcaa atttaagagt aaatgcatat atatatccgt atccttgacc agctatgaaa
    21121 gtagcaaatg tccatactcc cataagaaca cctaggagtt tcttaggtgc atacttactt
    21181 acaaaagagt taccaagtgg tgagaataac atttcaccaa aacttaatag tataccaaac
    21241 atgattatcc acattatact agctttagca gtttcagggg ctccaacacc tcttgtaaac
    21301 tctgccccaa caagcattaa aaatgcaaga cctaagaata ttaacccaag acctgtcttt
    21361 ttaaataaac tcatatctcc ttgtggtcta ctagcaagct taaaccataa tgctccaaga
    21421 actggtccta atactataca tacaagcgca tttaatgagt caaaccaagc aagaggaata
    21481 tcaaatcctc caatagtcat atctacaaat gctgcaccat aatcataaac tgcaagataa
    21541 gttagatacc agaataccca gaaaattaca gagaagaatg atataagtat aatagcccaa
    21601 attctcttct tatccatact tgtaagagga gacttatctt tttcttcaac tttttcagca
    21661 actacacctt ctttaaaagg tctctttcct gcatttccaa ggaatctcca tccatatgtg
    21721 aaccatattg cacctattac acaaagtaca gctgctataa agaaacattg agaaaatcca
    21781 agcacaccat tttttgcaaa agtcttggca taaagtatac caactgctgt agttccaata
    21841 aaagaaccta tattaacaaa agaatactgt actgaaaatg ctgtatcaag ttcttcttga
    21901 ttatcaaaaa gttgtccatt tactgcagac acatttcctt taaagaatgc agtaccaatt
    21961 gaaactaaga ttatcattgc atttaccata gaaactgtag ttgcaataga accaagatag
    22021 tatcctacac ccattataag catacctata ggtatagtat acctagctcc tatccatcta
    22081 tctgatatat accccccaat tataggtgca agatatgtga atgcaacaag gttagcttgc
    22141 attatagctg cttgtccctt atctattcca agtccaccat gaattacagc tgttgtaagg
    22201 aatatataga ttaaaaactt tgcagaataa tatgctgctc tttcaaatga gaaagttgtt
    22261 gagcagatat aaaatcccat aggaaattta cccttctttt ttactgttga gctcataagt
    22321 ttaaatcctt tcttaattat atttttatat ttttacgttt tatccaaact ctttctttta
    22381 atgaaagata tggttatatt attttgtaaa acaatttgta attattatta agataattgc
    22441 gcatttattt gtatagtata tattttcatg gaataaaatt aatatacttc tttagccata
    22501 aatttaaatt atataaatta cttgttttca tatatttata aattagtacc ttaatcatct
    22561 aataccatga aaaaaacttc gccatatgca attcttattt ttttacgtga tagtatttta
    22621 caaactaaaa tccccctttt gtagcaactt atgtaattac attttagcgc ttttttaaag
    22681 gagtctagaa taaagcaaca tatatttatt caaataatgt ttttatttac ttttaaattt
    22741 atatattact tcacccaacc aattctcaac ttaaataaat aaactactat ctattcacag
    22801 attatattta tcttttactt attagattta taataaacac tgtgaatcta aacataaaaa
    22861 actgttattt taaagtgatt acccatatat tcgcttcgat actatttgtt aaggttatac
    22921 tatttattta taatatatta ttcataaaat accttaatct gaaaactttt tcacgaatat
    22981 ttattttaca cctcccacta tttatttcac catgtaaatc gtaccataaa tatatactta
    23041 tatgcaagaa aaaaatctat taatcgacag taaataatta gaaaaattta aattatattt
    23101 gtcaagtata ttatataaaa tattttctat gaaaatataa gttaaattaa tgttcagaat
    23161 agttttttag atatgaaatc ttgattttct tattacttta cttacttgct caaatatatt
    23221 tttgtatgca gtatataata gtcaaatcgt acacttctta taactgcgtt gatttgaaaa
    23281 taatattaat agttaataga agaaaaaatt caaattaatt tttaaaaaaa ctataagtta
    23341 attgaatact tttttatgta cttaattagt tttataaatt caattatttt ctaaatttag
    23401 gtgtgattta ccatataaaa atgatttttt atcttaattt tctaaatata agtgaatgct
    23461 atcattttaa gtatcttata agcaatgtaa ctatatatat ctaataacta cttttttaat
    23521 atgcttaaac tatttataag caattatatt tatctgttaa cctaataact ttttcactaa
    23581 aaaataacaa tctattcaaa aataaactat agtgcttctt ctactttgtt tcaataaaat
    23641 actaaataaa tttcgtacat tcacaatttt tcaggctaca ctataaatat acaatattta
    23701 tcttagttat aagtctaaga atatttttag tcttattttg tcgaatattt ttaataaaac
    23761 ttcataattc taagcatatt ttttacactg tgttttcatg tacaaaaata atacttacaa
    23821 ataaacaaca taaataaaat ttaaataaga tggattctat tcaacatagt atccatctta
    23881 ttcattcaaa acctaaaagg attttttata atattataca ttttaaaatc taaataactc
    23941 attatagtat caatttcact taaagcttac aatacactta ttaatcttac tttataataa
    24001 aaagtataaa aacatctaca ataacaattt aaatctttaa gaaattatat cttatagtaa
    24061 ttcttcaata caatcaccct taatttttta tataatttaa ttatatactt tattttacta
    24121 gaactaatac acataaataa tacttaaaat agattaaata aaggatacta aaacacttta
    24181 ttgaggtata tgacttgaaa tatatgaact aacttcatta ggagaaatat ctaaaatagt
    24241 tgcaaattct tcatttaata acctttcagc ttctttcatt atattatcat ctgcttgatg
    24301 tgttttttta ccaatagatt ttacatactc tctgttattg tctatgcttc ttactaattt
    24361 tattaactct tcacatttac cacctctgag tattttttta aattgctcac ttcttaattt
    24421 ttcattatct atccatgagg tatccatatt aggaatatca tttattaatg aaagtacatt
    24481 aattttagaa agcaactttc tcattggtac tttttcatta tctacaggaa tttttattat
    24541 tgtattatta gagtaaatag gattcaatac ataatactct ttttttattc catttgtaaa
    24601 tcgttcattt gttatatcca tgactttgca gactcctgtc ataccataca ttatataatc
    24661 atcaatctta aacaaaaaca tcaccatcct taataaaaaa aaaagttttg acaactaaat
    24721 ccaccttgcc aaaactatct gctatatatt atatattaac acattttaag actttaatgt
    24781 aagtaaaact tatattatta aaattaaaaa atacatcaag cattgattaa tgtatttttt
    24841 agatttttat aacaagcata tcaaaataaa ttaagacagc ttatctcctg taaataccta
    24901 taaaattggt gcttggctat tcattgagta cccatcattt cttacatcat ttatttctaa
    24961 tatttcatca tttgtttcaa ctttagtaag ttttttaact gctccataag gttcttttaa
    25021 tgaaatttta tctcctcttc cagaaataac ccataaaatt ttataccctc taggtataac
    25081 ttgtagctta ttttcacctt taccatcagt aaagtagact aacaagttaa tctttttatt
    25141 attagcatac tcaaagactg gagaaaatct agtacctcca cctatcctaa ttctatcttt
    25201 tatatctttt tcagttttca ctttatatac acgtctaatt tcattatcac attctataat
    25261 tataatttca tgattatagt ttttcactat actaagaact tctttaatcg cttgtttaaa
    25321 ctcttcatca ctaatacttc cacttatatc aagtgcaact gctatttctg ccttatgact
    25381 tctaagttct cccctcaaat ctaaacgatt tggttgtctt ctatttcttc ttgttatagt
    25441 cttcttttta ttattttcaa ctgttcccat cattctatta agatataagt tccatggcaa
    25501 ttcactctta ctatttttaa gtgatgatat catactttct aaataagcag gaactttacc
    25561 tttttgagaa ctattaataa atttttcagt aaattctcta agggtatttt catctatctc
    25621 attagattca tcccatatat catgagttct ttctggacta taatcaattt ctatatctcc
    25681 atatttatca ctatcatctt cctcaccatc ttcatccact tccatcaaat ctaattcagt
    25741 ttgaatcttt tccacataat attcaaaagg ttcatatggc tcaagtttta aggaatattt
    25801 taaatttacc cactctaagg tagttgcata tggtggtaaa ttgtttagaa atttatttac
    25861 tactatatcc attgccatat taattgccaa tgtactatac tttcctttta actcctttgc
    25921 tctcatcaga tgcatagata atatatgatg aatttcatgt ttaattgtag tctccatttg
    25981 ttttatatca agcgttaaaa aaattattgg attaaaatat ataacatatt tagccccctt
    26041 aaaatttaca cctgtaggac tacttatatc aaatcttatc tctcttaaca tctgaaacaa
    26101 aaaatatcca taaaaattat cctcttcttc cataagactt aaattcactt tatctacaag
    26161 actaaaaaac tcatacttaa aatcctgtgg tatatctata tcaaatttct cattagcacg
    26221 atttgccttt aacatagaat gagtatttat aatttcactt gctttatcat aaagctcttt
    26281 tgcttgttta tcaaaataat tttccataca ttatcccctt attaaactat aagattcaaa
    26341 atatgatttt acaaactctt cattttctat agctttttta tacacttcag tataactgtt
    26401 tctaatatcc ttcataatac ctatcattaa gtccacagga tacattttta aaaatttaat
    26461 aaatctatta atatagtgat ttgattcata tttatcattc ttaatattta gctctaaatc
    26521 ttttagaata ttcatagctg atagataaag tcttgtatga ctctcttttt ttactctttc
    26581 tacaatagac tcatcaatag attctcctaa aaaaacttct tcataggata ttaatggttt
    26641 agaatctgat tcaataaaac ttataaattc ttctgcgata accttaccta cattaccctt
    26701 tataacattt aaaaatactg ctctaggaat agaattatta ttttctttat aaactttata
    26761 aattttagat actctttcat aacttctagg agtagctctt acatcatctt catttatttt
    26821 atgcagatat tctggaaaag tggaaataaa ctcgataact tttctttcaa tcccttcatc
    26881 tattgcccat tttatccatt gtgtatggtc actctccata tttaaccaaa caaatctatt
    26941 ttcttgagct gcatccatat ctaccacttg ataatcaaaa tctgaaccat atttacttga
    27001 tgggttcatt gccgctaaaa tctttacatc atcatgcaat ttatatccat taatctctct
    27061 atttaaaatt agattcataa gttcttgctg tactgtatgc tcacaacgat ttatctcatc
    27121 tataaataaa agaactatct tacctttaga tatctcttca tcaatttccc ttaatttgtt
    27181 atgaacagca tatacggttg ttttcttttc agtcttatat ccactagaat taactcctac
    27241 ataagattct atagtaggaa gacctcctat ttcaccctct ttaagtaggt ttccatcaat
    27301 agcaactaaa ctccaatcat tttctttggc aagcttattt gccaaagctg tttttcctat
    27361 cccactttca cctactatta aaggtacttc tccagtggat aatattaagt caacgctttt
    27421 taatgtgtct ataaaattca tttttatctc tcctaaacaa tctttaattt ctcatctaca
    27481 gctatttttt ttgccgtttt gcttccatat ttataaataa acataatttt atctattggt
    27541 atattctcac tatgtctatc tataacacta caatttaaaa aatctctaat atacttctct
    27601 tcaacatctt cttttgataa tacttctttt aatacttcct ccaattcatc tttagatatt
    27661 ttctttacaa tgtatttaat cactaagata ttcactttta aaaattccaa cattttattc
    27721 ttatctaaat cagttataaa gctaatagct gcttcattat tttttatagc tataagttct
    27781 gcactgtaac taggtgaatc tatatatctc aaggcatcat aacttattct cacagcctcc
    27841 tcttgtacac tttcataagg ttgttttata aactttatcg aatcataatt ttttcttact
    27901 gctaataact gtaactcttc acttggattt ttaacatatt taattgccca acctgcttga
    27961 tttatagcca tttcaataac tttatcagtt ggatttttga tataatccag tatactccat
    28021 ccctcattta ctgcttttat catcatctct tctgttggat tatctataaa tttaattgct
    28081 ctaatattat tatctattgc tagttcttgc atctctctag ttggattatt tatatattct
    28141 agtacaagtc cattttcttt aatagctaat aatttcattt catcagttgg attatctata
    28201 gttgatataa tattaggatt attttttatc atttcaataa ctcttgattt ttccataaca
    28261 tgcctttctt tatataatta tttttctctt tatactaatt ataataattt attcctattt
    28321 atataattgt ttcttattat aattaatata ctttttaagc aaatttaaac agaataatta
    28381 taccaatata taaaaaaatt tctagaaatc aataaaatta agtctatata cataaagaca
    28441 tctttaatat ttataaagtc agacagtaat ttaatacttt tattgacaaa aaaagacaat
    28501 ccataaaaaa ttgtcttttt tcaacaaaat tcatcaatgt aatttctaga tatcgttgct
    28561 atccccatat aattattgaa attactaaga tatagtattt tgttatttaa atataaactt
    28621 attctaacat ctatttattt agatgttttt ccataatatc taaaattatc taatctattg
    28681 taatacttac tttttgagat gatattgttg cattttcatc ttcaacttca gcccaaaaag
    28741 tatgagtacc tactattaat gaataaagta caaatgattt ctttacttca ttaggatttc
    28801 taacacttag ttcttcattt acaatttttt gcccatccat atatacattt aaagtttttg
    28861 cattattcat tgctggaacg attacctcaa catcaacttt attaggatta ggtgatatct
    28921 taattgatgg tggtattata ctatctacta ttatatttac ttcttcagat tttaaacatt
    28981 taccattgcc atcttcaaga actgcaaaat atgtataaaa accttctttt ttgtcactca
    29041 tatcaaaatt aatattttgt aattctgaac ttcttactaa atcttttgtt tctataggaa
    29101 cattattctc aaatagttcc aatttagtcg cagaattatt aggaggaaca gaaacattaa
    29161 tattaaattt accattatta ctcaaggttt tatcagttga tatttctgga gactgtaaat
    29221 ataattctga tgaattatcg atttgaccca aatcgaacat tttcgaatca ccattaattt
    29281 caacattttt ggagattaat tcgggagata gtttatgccc cttattatct actaggataa
    29341 ttgatttaat aattgctact ttatcatctt ttaaattatc ctttatctgt aaataaattt
    29401 tgtctgcact tgataggcta acattaagtt ctttctctaa atgtgctaaa tcaattacaa
    29461 aagtgatttc tgaaccatta tttacaccat ccaatggaaa atctcctcca ctataagata
    29521 ataatggact gtatactact gtttgtttat taccattttt ctcatatact agacttactt
    29581 gcaactgttt tctgttatca tgttgcatag tgaatctcac taatttggat ggtgtttctt
    29641 ttttgcttat tactacatat tcagcttcat tatttaagaa tgctccttgt cttgcattac
    29701 tatttgtaaa gtctaaaact gatgattttt tatttaatgc atcataagcc atccaaacaa
    29761 atccattgtt tgcatagtca ggtccatgag aattagcaat cttaaaagca cctttttcac
    29821 catcatcaac cttaccattg ctattgatat ctatccatat attgtcattg tatcctacaa
    29881 tagtcatttc atgtgcacct tgattattaa tttgataaat tgctttctga tttacataac
    29941 tatcatcgtc tttagtcgag gggtcattag aaatttgttt ataattagca tctgagaacc
    30001 aagtatagaa atttaaaata tatccattta gtaataatct cttcgcatca tccaagtttg
    30061 agtctttgtt tgatgtaata aaagaatttg gcttattatt tttattaaaa ttaaccctta
    30121 atatttcatc tacctgatat ttagttgcat ttctccagat attttcatct ttagcccatt
    30181 ccctataatt tttaggatct ctgcctaaac ctacataagg aaagtcagct aatgtagcac
    30241 aaccatgtgt tttaaaaaca ttataattct gataagcaaa tgctcctgca tctttgccat
    30301 cgtttatgaa attataagac cacttaggtg aaaatatttt agaatctata ttttttccac
    30361 tcacatcttt tacactccaa tcatttacaa gagcagtcat ataagtcata gtatagtatg
    30421 ctgttgcata ggatgcacag cttgccaaag aaccttggct ccctatgtta ggaaaatact
    30481 tagtttggct attgtcaaca tttgatggaa gtttaatatt ttctgaattg tcttcaagtg
    30541 aaaaattaga agtgtctcct tgtttaacta tttcatctcc taattttgct ggagatacat
    30601 tttcaataat ttgttttgag ttgatattct taattctttc taatgcaata ctatttaaat
    30661 taaccttttc tgttaattta gaaatttcca gttgcttagc tctatcattg tcagtaaaat
    30721 ctggtaacca taatttctct tctgaattgt aattattttc ataggcatgc accaaaaatt
    30781 tttgattaaa tgttaaagtt gtaattgttg ctagtaataa tgctattctt ttctttttaa
    30841 ttttcttcaa attaatcccc ccaattttac tatacatttt tgttaaaatt tattttacaa
    30901 cacaatttta attatttcaa taaaaatata taagcaaaaa tgatattttt ttatgattaa
    30961 acatagtatc aaaactaaaa acaatataaa acatcttgta tttacttgga aatagttagt
    31021 ttt
//
LOCUS       DBGJFK010000043        30928 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.043, whole genome shotgun sequence.
ACCESSION   DBGJFK010000043 DBGJFK010000000
VERSION     DBGJFK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30928
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.043"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            63..1607
                     /locus_tag="ACOIAP_002269"
     CDS             63..1607
                     /locus_tag="ACOIAP_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HGZ2639152.1"
                     /translation="MRNFKKKLMFFLFICIILQITCTTSVYSLCKIYKNNSVNNFEFI
                     VSNNQLISKYALQMILIMATICIILIFYIIYDKLNFKIKLQKIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITNRLKIIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFEKNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTISVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVVEMAKELGMKVISEGVETEEQFELLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLIRG"
     gene            1783..2151
                     /locus_tag="ACOIAP_002270"
     CDS             1783..2151
                     /locus_tag="ACOIAP_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2639153.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEILKLITENLKGEL"
     gene            2153..2878
                     /locus_tag="ACOIAP_002271"
     CDS             2153..2878
                     /locus_tag="ACOIAP_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639154.1"
                     /translation="MDKNINNISQDGIVEFKGVNKSYGIKTVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIETKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEVIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            2872..3636
                     /locus_tag="ACOIAP_002272"
     CDS             2872..3636
                     /locus_tag="ACOIAP_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639155.1"
                     /translation="MLAKLLKYELKASGRVFIPLYIAILIVAVFNGIFMNTNILQIQG
                     IAILVLTSLFMALAVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVVSFIVAIFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILVLLLVMLTSYS
                     LFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPKENTNMIYH
                     FYQSSHVMFAILGDIVVIVALFFATKFILDKKLNLE"
     gene            3882..5132
                     /locus_tag="ACOIAP_002273"
     CDS             3882..5132
                     /locus_tag="ACOIAP_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2639156.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLENELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKVQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTELYEESEKVNIVDGIKSVIK
                     NKSTWYNSMIMLSFVGLTSAFISLWGVRYIMDVYCVSKSFSAFIVSFFTYGFIFGSLI
                     MDFVFAKIRSSKFNIIKYGAIIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNVVDGYKKSFVV
                     FIVLSIITIVSSHIGVKNDDFKAL"
     gene            5324..6208
                     /locus_tag="ACOIAP_002274"
     CDS             5324..6208
                     /locus_tag="ACOIAP_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGZ2639157.1"
                     /translation="MDTTKIDDISKLDLKNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYIEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFAARVWCNTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            6567..7184
                     /locus_tag="ACOIAP_002275"
     CDS             6567..7184
                     /locus_tag="ACOIAP_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HGZ2639158.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTADSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQNFKVPYTDAINTFKDKYKDADVVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTENLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKIDSKKGTVLKVEKED"
     gene            7290..9821
                     /locus_tag="ACOIAP_002276"
     CDS             7290..9821
                     /locus_tag="ACOIAP_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HGZ2639159.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSDYKVNLFDVIEHKQEDILAKISVSQGVLFGTPTILGDALKPIWDILVSL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMKAVKPFAVNFKPSNEEIDKLNSY
                     TGKFLDKLNATFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEIEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKAWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVI
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVIFKDGDSVDC
                     DMVVFSIGVRANTQMAHDTSVKIDRGIVVDKTLQTTVKDIYACGDVAQVENTSLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDDSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            10032..10652
                     /locus_tag="ACOIAP_002277"
     CDS             10032..10652
                     /locus_tag="ACOIAP_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGZ2639160.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFVGCLLSWIGSGLGTASLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDVKDFVPAMLAGKFVMFIVISYIASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHQSDKDDKMI"
     gene            complement(10819..11355)
                     /locus_tag="ACOIAP_002278"
     CDS             complement(10819..11355)
                     /locus_tag="ACOIAP_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HGZ2639161.1"
                     /translation="MIKETHERGGYILALLILPFINNLYLVKYDIAYKIVLIIVYIYF
                     AYLGSLFPDIDMRGSYISKKFTLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKLISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11468..12172)
                     /locus_tag="ACOIAP_002279"
     CDS             complement(11468..12172)
                     /locus_tag="ACOIAP_002279"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HGZ2639162.1"
                     /translation="MKKKILIPVIMSLFIISQCITSFAFTPENNKFKVKPLPYAYDAL
                     EPYIDKETMKLHHDKHYQAYVDKLNVALEKYPELYNYSLCELLQNLDSLPKDIATAVR
                     NNAGGAYNHKFFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKAALDVFGSGWA
                     WLVATKDGKLSIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNAV
                     NWNGALENYKNLKSQD"
     gene            12345..14228
                     /gene="asnB"
                     /locus_tag="ACOIAP_002280"
     CDS             12345..14228
                     /gene="asnB"
                     /locus_tag="ACOIAP_002280"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HGZ2639163.1"
                     /translation="MDGNISIYYKGDISKKENIKFKIKESLNNINNTRVSSRIEYKSE
                     AKIFDFERFNVIDVIYGNKPFEKYGKVIVFNGNIYNNHEIKEELIKRGHSFTTGDDIE
                     VLLASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKESAIIFSS
                     EYKFILEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKR
                     YNKLEFRSSTKFFYTKNHLGNRDVDKEEVRNIVVDSIRNHMEEHKEIGTFLSGGIDSS
                     IITTVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKALPN
                     VIYSLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVN
                     SPTYIKGILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEK
                     NIYEYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFL
                     YKDVFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSL
                     GGIVKETISNSNVDEFIDKKYVIKLLDMHLKGHRDNSRKIWTIFTFCLWHQLFIEHKN
                     VEY"
     gene            complement(14319..15755)
                     /locus_tag="ACOIAP_002281"
     CDS             complement(14319..15755)
                     /locus_tag="ACOIAP_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HGZ2639164.1"
                     /translation="MICTIKPLKISIKKSNEPLIEFMSNTTYQNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPIIPYIRLSSLNINFDKEQTDKMLKIFNIYDSAK
                     FNSWDLYNINFPCKIENDTLNWTKKIAFKNTLDLFSMSMPNCTPSIIKNFAVKLLCWI
                     EYFLPKLFYNKVNTNISPKILYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSNIFELSRKTPNILEIPFERHIANINYNENTNKTSHPMNKPNSENTFNNTNLI
                     SKKIVQGEEVELSYEELAKLSASVVMIVVCNKENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSGYDLAVIKVDRKCKPIPVKIGKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            16081..16662
                     /locus_tag="ACOIAP_002282"
     CDS             16081..16662
                     /locus_tag="ACOIAP_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HGZ2639165.1"
                     /translation="MMGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLD
                     TAAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPG
                     EISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVA
                     EIYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            16701..17279
                     /locus_tag="ACOIAP_002283"
     CDS             16701..17279
                     /locus_tag="ACOIAP_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HGZ2639166.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLEAMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            17365..17994
                     /locus_tag="ACOIAP_002284"
     CDS             17365..17994
                     /locus_tag="ACOIAP_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HGZ2639167.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGAGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            17984..20743
                     /locus_tag="ACOIAP_002285"
     CDS             17984..20743
                     /locus_tag="ACOIAP_002285"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HGZ2639168.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMVSKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     LNSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQARKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKEE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            20830..22392
                     /locus_tag="ACOIAP_002286"
     CDS             20830..22392
                     /locus_tag="ACOIAP_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HGZ2639169.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKNGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDKVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNVEFEEANIIEEKTSFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFNFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGVIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIIFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            22393..23529
                     /locus_tag="ACOIAP_002287"
     CDS             22393..23529
                     /locus_tag="ACOIAP_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HGZ2639170.1"
                     /translation="MGININSFSKDKNSVDVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSSQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            23591..24667
                     /locus_tag="ACOIAP_002288"
     CDS             23591..24667
                     /locus_tag="ACOIAP_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HGZ2639171.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETREFIYNEKKELSFINLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMKNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNEINPHFLWAK
                     KTLILSKIYGVLNEGVDYEELLKF"
     gene            24645..25883
                     /locus_tag="ACOIAP_002289"
     CDS             24645..25883
                     /locus_tag="ACOIAP_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HGZ2639172.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDIGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLIATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYTITKLDTILSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITIDNKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQCDVYYHST
                     TRSPIINIDKHNYPIRSKFMLKSFYNMDIQNYIYNIDKQNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            25937..27025
                     /locus_tag="ACOIAP_002290"
     CDS             25937..27025
                     /locus_tag="ACOIAP_002290"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HGZ2639173.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYVKSKYNINLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNDKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFVL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDV"
     gene            27053..27844
                     /locus_tag="ACOIAP_002291"
     CDS             27053..27844
                     /locus_tag="ACOIAP_002291"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2639174.1"
                     /translation="MIVFSDLDRSIIYSNKFLSADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIYKFKDYLNVDGITNFKVAEDTFFYIVVDFSKFNLESIKEYTNV
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAIGDSIMDYGMLNISNK
                     AYLLKHGDINKNEIENSFLSSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(27959..28513)
                     /locus_tag="ACOIAP_002292"
     CDS             complement(27959..28513)
                     /locus_tag="ACOIAP_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGZ2639175.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDDVCISVWAMTPPSF"
     gene            28707..29909
                     /locus_tag="ACOIAP_002293"
     CDS             28707..29909
                     /locus_tag="ACOIAP_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HGZ2639176.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGVTEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            29966..>30928
                     /locus_tag="ACOIAP_002294"
     CDS             29966..>30928
                     /locus_tag="ACOIAP_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGZ2639177.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISEHKINILIGLE
                     GLSHIGSNIDSIDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVHKME
                     NLGMIVDVSHLNEKSFWDLMSIASKPVIASHSNAKSLCDVKRNLTDNQLKEIANTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NSSMPSVDGLESTHTAHNIVVELENRGYKKRDIDLISSGNFYRLF"
BASE COUNT        12083 a         3140 c         5364 g        10341 t
ORIGIN      
        1 aaacttttga gatgtacttg tttgccaata aaatagaggt gttttaatag gaggaaattt
       61 ttatgaggaa ttttaaaaaa aaattgatgt tttttttatt tatttgtata attttacaaa
      121 ttacatgcac aacatcagtc tattctttat gcaaaatcta taaaaataac tccgtaaata
      181 actttgaatt tattgtgtct aataatcagc ttattagcaa atatgcatta caaatgatac
      241 ttattatggc tacaatatgt attatactta tattctatat aatatatgat aaattaaatt
      301 ttaaaattaa attgcaaaag atagcatata cagataatct tacaggagca aatactatag
      361 ataaatttgt aattgatgct aacaaaatac tatgtaaaaa tactcaagta aagtatgctt
      421 tattatatat agatattgat aaatttaaat atataaatga cctatttgga tatgaagttg
      481 ggaatgaaat tttgcgtaat ttaacaaaga ttattaagag taatatattt gaagaggaaa
      541 tgtttgcaag aatatctgcg gataatttta ttataattat gaaatatata gaagaagaag
      601 atataacaaa caggttaaaa attatatttg aagaactaga cttgtttaat aataatcagg
      661 aagaaaagta taagttagtt ttaagttgtg gaatctattt tatacttcca gaagatagag
      721 atatcaactc aatcatagat agagctaata tacctcataa aatggcaaag ggaggacata
      781 aaagttcata tgcattttat gataataaga ttcatgacca agagataaaa gaaaaagaga
      841 tggaaaatac aatgttttca agtttagaaa ataaagaatt tattatatac ttacaaccta
      901 agatagagct taatacagga gaaatacaag gttcagaagc acttgttagg tggaaacgcc
      961 ctgataaagg attaatacct ccaaatgaat ttataccatt ttttgaaaaa aacggttttg
     1021 ttataaattt agatttatat gtgcttgaag aagtatgtat ataccttaga aaatggattg
     1081 atgcaggaat aaatccagtt accatttcag ttaatgtttc aagaatacat ttatattgca
     1141 ataattttat agaaacatac aaaaatataa ttgataaata taacatacct gcaaaatata
     1201 tagaacttga attaacagag agtatcatat ttgataattt tgatatttta attgacataa
     1261 tgaataattt aaaaaaaata ggatttttga tatctatgga tgattttggt tcaggatact
     1321 catcattaaa tatgttaaaa gaaattccta tggatatatt aaaacttgac caaaaattta
     1381 ttatggaaac ttataatagt aaaagaagca aaataattgt tactaaggta gtagaaatgg
     1441 caaaagagtt aggtatgaaa gtcatatcag aaggagttga gacagaagaa cagtttgaac
     1501 ttttaaagga agtaaaatgt gatatggcac aaggatattt atttggaaag cctatgccaa
     1561 ttgaagaatt tgaacattta attgtatcta atttgataag agggtaatta atctgtatta
     1621 taaaaattta gtaaattgtg ttaaaaatgg actctaatgt agtgttcatt tttttttgta
     1681 aaatttttta tgcttttatt aaagagtcat tgacatatac tctgtattat tatattattg
     1741 tattaacgaa ctaatacaat agtgtaaaaa ggaggtatga atatggaatg ggaacttgat
     1801 aataacaaac ctatatatat acaattagta gaacatttaa agttaaaaat aatttcagga
     1861 gaaattaaaa taggatctaa attagaaacc gtgagagcac tagcagaaga tgctgaagtt
     1921 aatccaaata caatgcaaaa ggctttaaca gaacttgaaa gacaaggttt agtttatagt
     1981 cagagaacca aaggaagatt tgtaacagat gataaggaaa aaataaaagc tatgaaagag
     2041 gaaatagcta atgtggaaat aaatacatta aaagtaactt tagaaaagct tggatatgat
     2101 agagatgaaa tactaaaact tattacagaa aatctgaaag gagaattata aaatggataa
     2161 aaatataaat aatatttctc aagatggaat agttgaattt aaaggtgtaa acaagagcta
     2221 tggaattaag actgttttaa agaatattga tttaaatata ccaaagggaa aaatagttgg
     2281 gctgttagga cctaatggaa gtggtaaaag tacaatgatt aagttaatga atggattgtt
     2341 acagcctgat aatggtgaaa ttatgataaa tggaatgaaa ccatccatag agactaaaaa
     2401 aatagtttca tatttaccag aaagaactta tttaaatgat tggatgaagg tatctgattt
     2461 gcttaaattt ttctatgact tttatagtga ttttgatgtt agaagagcaa atgagatgat
     2521 taaaagttta gatattgatg taaatgaaaa actaaagaca atgtctaaag gaactaaaga
     2581 aaaggttcaa cttatcttag taatgtcaag aaatgcaagt atatatatat tggatgaacc
     2641 tataggaggt gttgacccag ctgcaaggtc atatatactt aagactatat taaaaaatta
     2701 ttctgaagat agtactttgc tgattgctac ccacttaata agtgaaatag aaaacatatg
     2761 tgatgaggta atattcatat caaaaggaga aatagtgtta caaggagacg ttgaagcaat
     2821 aagagaagaa aaaggaaaat ctatagatgc attatttagg gaggaattta aatgttagct
     2881 aaattattaa aatatgagtt aaaagcaagt ggaagagtat ttataccgtt atatatagcc
     2941 atattgatag tagctgtatt taatggaata tttatgaata caaatatact tcagatacag
     3001 ggaatagcaa tactagtatt aacaagtctt tttatggcat tagcagtttt aactattgta
     3061 gttacaattc aaaggtttag aaaaaatctt ttgggagatg aaggttattt aatgtttact
     3121 cttcctgtta gcactagttc acttatattg tctaaatgta taacagcact catatatgct
     3181 gtagttagtt ttatagttgc aatattcact tttggagtac ttatgctttt tggtacttct
     3241 ggaattttat tacccgaaat tttagattta tttaacacta gttttaaatg gatttctgaa
     3301 aactttttag atattttagt attattattg gtaatgctta cttcatattc attatttatt
     3361 ttgttgttat atacatcaat ttcaatggga caattaccca aatttaataa acatagaaat
     3421 atagtagcat ttgcttcttt tatagctata aatatagtaa tatcaattgt tggagatgca
     3481 gttggaagca ttttaccaaa ggaaaataca aatatgatat atcattttta tcaaagttct
     3541 catgttatgt ttgcaatact tggtgatatt gtagttatag tagcattatt tttcgctaca
     3601 aaatttatat tagataaaaa attaaattta gaataaatgt ttttatatgg agctatcttt
     3661 tgagtaatgt tcaaagatgg ctcttattat ttatatattt aattcatgca tataatatga
     3721 ataaggtttt atttctagtt aaatatatcc atatgttgta taatgatatt gtgtgtaaaa
     3781 atttgtaaga ataactatac acttgatata agtaatatca aaacaagtgt tttgtaagtt
     3841 atattaaaaa aattaaaaat atatggattt aaggagaagg tatgaaaagt tatacaaagg
     3901 ctaagtggag tgtttggggt ataattacat tttcatttgt tttagtatta tttttaagaa
     3961 tgtcaactgc tgttgtttca gacaatttag aaaatgagtt aggttttaat tctatacaaa
     4021 tttcaaatat agcatccttc tgtctatatg catatgcatt tatgcaaata cctgcaggaa
     4081 ttttgattga taaatatgga gcaagaaaaa ttagcagtct tggaataata atggcaagtt
     4141 taggttcaat tttatttggg ttgattcaaa gtatagaatt agcatatatt tctcgtgtaa
     4201 ttgttggggc aggaacatca gtaatattac tttgtatttt aaaagttcaa ggaagatggt
     4261 ttaataaatc agaatttgcc tctgcaacag ccaaattttc atttgtaggg aatttaggag
     4321 gagttcttgc tacttttcca cttgtgttcc tgtctgaact tgttggttgg agaaactcat
     4381 ttttattaat tggtataatt ggtgttgtga ttggatgttt tatgtatatt attgttagag
     4441 atacaccaaa agagtatgga ttcaatgtag atactgaact atatgaagag tcagagaagg
     4501 ttaatattgt tgatggtatt aagtctgtta taaagaataa atcaacatgg tataattcaa
     4561 tgataatgtt atcttttgtg ggtcttacaa gtgcatttat aagcttgtgg ggagtaagat
     4621 acataatgga cgtttattgt gtgagtaaga gcttttctgc gtttatagta tcatttttta
     4681 catatggatt tatatttggt tcattaatta tggattttgt atttgctaaa ataaggtcta
     4741 gtaaatttaa tataataaaa tatggagcaa taatagattt gttcatatgg attgtaattg
     4801 tagttgtata tcaggtaaaa ccaccaatta tagttttacc aatatcattc tttattatgg
     4861 gatgtatagt tatgtcacat ctacaggttt ttaatgatgc caagtataaa aataaagaaa
     4921 tttattctgg attggcaact agtgttatta atacttttga atttatagga agtggaatta
     4981 ttaatttgat tatagctatc tctttacaag taaattcata taatgtagtt gatggatata
     5041 aaaaaagctt tgtagtattt atagtactaa gtattataac tatagtatca tctcatatag
     5101 gtgtgaaaaa tgatgatttt aaggcactat agtgttttac taatagttta atttaatgtt
     5161 atattttttt atatatataa caagtggttt atatttttct aatatgtata attggaatat
     5221 aaatcttgtt tactatgcac aaatggtatt gtattatatt aaatagaaaa taagaacttt
     5281 aaactataat attggttcta aaatataagg taaggagttt tttatggata cgacaaaaat
     5341 agatgatata agcaagttag atttaaagaa tctagatatt aataagatgg atatgggagg
     5401 tataatggaa agtctgttgg aatgggctac tacaagcgga gtaaaactta taataggtat
     5461 acttatactt tctattggat ttaaaataat aaaaaaattt gtaaaccatg ttatgctatt
     5521 acttagtaaa agagatattg atttaacttt aagaaggttt ttgaagtctc ttcttttgag
     5581 tgtacttaaa gttgctgtta taatcattgt tctagaatat tggggaatga gtttgtccag
     5641 ttttgctgct gtgatagcat cagccggggt agcaataggt ttggctttac aaggtagttt
     5701 atcaaatttt gctggaggat ttattatact tttgattaga ccttttaaag taggagatta
     5761 catagaagca gcgggtcatg gaggaaccgt tgaacaaata ggactttttt atacacaatt
     5821 ggttactcca gataataaac agatacttat acctaatggt tctgtatcaa atgacagcct
     5881 aataaactat tcagcaaaga atactagacg agttgacttg acttttagtg taggatatga
     5941 agatgatata ctacatgtta gaagagtact taaagatatt gttaataacc ataaattaat
     6001 aataaatgaa ccagaaccat ttataggagt agtagaacat ggagataatg ccattaaatt
     6061 tgcagctaga gtttggtgca atacagaaga ttattggaca atttatcttg atttactaga
     6121 agaggttaaa gttaggtttg acgaagaagg aattacgatt ccatatccta aaatggattt
     6181 aacagtaaaa gaattaaata aaatttaatt ctttgatata gtgtttaaat ttaagaatat
     6241 catatagata tttttataag atttgtaaaa aaataataag tactgttatt ttgtaagtaa
     6301 aaatataaaa aatatgagtg tctcaaaatg aactttttat ttcatgaggc actctttttg
     6361 tgtaaaatca aatacatttt tattatttca acaatgaaaa agagacttgt ttatattttg
     6421 agacagtatc ttttttgtgt agctttaatc ttagtaagta taaagtttta aaatcaataa
     6481 aatagtagaa atttttaata taaagggtaa ataaagggtt tagagggcat aatatagaat
     6541 aaattaatta tttaaggagg atttttatgt gtaaaaaaac gtatttatta gtggtaagta
     6601 tacttatagc aggtttatta actgcatgta gtgggagtcc aactgcagat tcaggacaag
     6661 cacaagataa tacaaaaaag gaagcaaatg cttcaaataa tgctttaaaa gatgaaaaaa
     6721 ataatgaaaa tttaatggaa caaaatttta aagtgccata cacagatgca ataaacacat
     6781 ttaaagataa atataaggat gctgatgtag tagatttaag tcttgaaaga gatttaaata
     6841 aatttgttta tactgtggaa ggtgtagatg ataataatga atataagatg aaaattgatg
     6901 ctaatacaaa agatgtattg gaagataaaa cagaaaattt ggattcagaa gatttaaatg
     6961 gagttgcaag aaaagaaaaa ttagatttaa atgacataat tacacctcaa caagctatgg
     7021 aaattgcatt aaaagagcaa aatggaatgg ttaaagaatg gagtttagat aaagatttag
     7081 atgttacttt ttataaaata agaatagata aagataaaaa tgaatatgac ataaaaatag
     7141 attctaaaaa gggaactgta ttaaaggtag aaaaagaaga ttagaagatt taaattatct
     7201 ttaaaataat tttttttgaa taaattttgt ttaaaatata acaagcaggg tataaagaga
     7261 ctaaataact attttaggag gagtacggta tgtcattaaa atcactaaaa ataaaagaaa
     7321 atttatattg ggtaggttcg cttgaccctg atttaagagt atttgacata attatgtata
     7381 caccttatgg aactacttac aattcatatg tattaaaagg aacagaaaaa acagttttat
     7441 ttgagacagt taaagataag cattttgaca attatattga aagattaaat gatttaaata
     7501 tagattttga aaaaatagac tatattgttg taagtcatac tgaaccagac catgcaggaa
     7561 gtgttgaaaa gcttttggat ttagctaaaa atgcaaaagt agtagcttca gaaacagcaa
     7621 ttaaatatct taaggaaatc gtaaacaaag attttgaata tgttgcagtt acagatggag
     7681 atacattatc aattggggat aaaactttag aatttttctc tgtacctatg cttcattggc
     7741 cagatactat atacacatat ataaaagagg acaaaactct tgtaacatgt gattcatttg
     7801 gtagtcacta tagtaatgat aagatagtaa atacacttga tgaaaatgaa gaaaaggatt
     7861 acctggatgc tttgagatac tattatgatt gtataatggg gccatttaaa ccatctatgg
     7921 taactgctat agaaaagata aaagatttag atatagacac tgtatgtcca ggtcatggtc
     7981 cagtattaac tgaaaatcct agaaaaatta tagaccttta ttacaattgg agtgtaaatg
     8041 aacaaataaa gttagaaaaa gaagttacaa tttgttatgt ttctgcacat ggttatacga
     8101 aaattatggc agaagctata aaagcatata ttgaaaaaaa tagcgactat aaagtaaatt
     8161 tatttgatgt aatagagcat aagcaagaag atattttagc aaaaatatca gtatctcaag
     8221 gtgtattatt tggaacacca acaatattag gagatgcatt aaaacctata tgggatatat
     8281 tagtatcgtt aaacccagtt cttcatggtg gaaaagttgc ttcagtattt ggttcatatg
     8341 gatggagtgg agaaggtata gaaaatgcta tggagagaat aagtcaactt aggatgaaag
     8401 cagtaaaacc ttttgccgtt aactttaaac catcaaatga agagattgat aaattaaatt
     8461 cttatacagg taagttccta gataagttaa acgctacttt tggaagtaaa aagaaaacta
     8521 agaaatttaa atgtgtaatt tgtaatgaag tttttgaagg tgatagtgct cctagtgtat
     8581 gccctgtatg tggagctaag gaagaccaat ttatagaaat tgaagaagat gaagttactt
     8641 ttagaaaaga tactgatgaa tacttcgtaa tagtaggaaa tggagcagct ggtttttatg
     8701 cagcagatgc aataagaaaa agaaataaaa cttgtaagat aactatgatt tctaatgaag
     8761 atgagttaac ttactataga cctgcacttt ctgatggtat aaatgaagaa cttggctcag
     8821 atttctatat ggaagataaa gcttggtatg ataaaaataa tatagtagta atattaggaa
     8881 cgaatgtaga taaattagat gaagtaaata aaactattat agtgaatgat ggagctatta
     8941 aatttgataa gcttgtaata gctacaggaa gtagaaactt tataccacca attaaaggtc
     9001 atgatttaga aaatgtgttt acacttagaa atataaaaga tttatatagt gtaaaagaag
     9061 cactagaaaa atctaagaaa gttgtagtga ttggtggagg tttattagga cttgaagctg
     9121 catgggaatt tagattaaaa ggattagaag tagtagtaat tgaagcaatg gatagtatac
     9181 tgtcaaagca acttgataaa gaaggtagta aaatattaga acaatgtgta agagatacag
     9241 gaatagatgt aagattaggt gtagcagttg atggtattga aggtgatggc aaagctcaaa
     9301 aagttatatt taaagatgga gatagtgtag attgtgatat ggtagtattt tcaattggtg
     9361 taagagcaaa cactcaaatg gctcatgata catctgtaaa aattgacaga ggtattgttg
     9421 tagataagac attacagaca actgttaaag atatatatgc ctgtggagat gttgcacaag
     9481 tggagaatac tagtttagca atatggccat cttcagtaga aatgggaaaa atagcagggg
     9541 caaatgcaag tggagataat ttgacatttg aaagtgaagt atatccagtt tcattagatg
     9601 caatgaatgt aaaagtattt agtattggta atatacaaaa ttttgataaa gaaatttcat
     9661 caaaagatga agggcaaaga atatataaaa aattatttat gaaagacgat tcattggtcg
     9721 gagctatact tataaatgat ttaagttgta ctgttaaatt gataagatta atatctgaaa
     9781 aaggtgattt tgaggatatt atgaaggctg atatactata gtttaaatat actagaacaa
     9841 aaagtcttaa aatatgacaa ttcatatttt aagacttttt tgttataata tataataaaa
     9901 taattacacc ttaactgtaa atttatatag attatttact ttttattaat agattcattt
     9961 tttgagatta gtatataatg aacatataga gtatataata atagttaaag ttaaaaaagg
    10021 ggaaaagcaa tatgcagtat atacaagaat tacttgattt aactcaaaat tattgggtgt
    10081 tagccacaat aataggtttg ttaagtgcat ttatagaaag ctttatacca gccttaccac
    10141 ttgttgctat agttacagca aatgctgcaa tacaaggatt atttgttgga tgtttgttat
    10201 catggattgg ctcaggactt gggacagctt cattattttt attaataagc agatttaatg
    10261 atagtaagct ttttaataaa ttgagaaata gtaaaactga aaaagcaata agttggatgg
    10321 ataaacaggg atttaaatta ttatttatag catatgcctg tccatttatg cctggttgtt
    10381 tagttactat cgcatcagct tttggtaaaa aagatgtaaa agattttgtg ccagcaatgt
    10441 tagcaggaaa atttgtaatg tttatagtta taagctatat agcaagtgat atagaaggtt
    10501 ttataacaag tcctttaaag atagcatcat ttatattatt ggtgtttttg tcatggaaga
    10561 ttggaaatag agtaaataaa aatcttgaaa atcataatta tgatttccat cataaaaaac
    10621 atcaaagtga taaagatgat aaaatgattt agcttgtacg agataaaacg tatcttaaaa
    10681 tgatttagta ctaaattatt ttaagatacg ttttatttgt tgtattaaga tataaaattt
    10741 tttagctctt ttgtgaagta aaatatacaa aacttatttg tatttagttt gaaatagtgt
    10801 tacttattgt ttctataact ataataaaat ataaaattga tatccaatca aaaaaataac
    10861 tatgaagttt aatagcttag atattaattt ttctgttttt gagttagttt ttataggtag
    10921 taaagaaatg tttatagtaa tgggataaaa caattcaata ccttctttag taataaggtc
    10981 aagacacaag tgagatagat atcctattat aaatccactg gacaaacatg agaaaactat
    11041 attattgtta gtgaagattg ttagagattt aaaaaaacta taaataagta ataaggcaat
    11101 tagactgtga gtaaatcctc tatgtctaaa cctgcttcca aataatttgt atattaacgt
    11161 aaatttttta cttatataag aacctctcat atctatatct ggaaacaaag aacctaaata
    11221 tgcaaaataa atataaacta taattaatac tattttatat gcaatatcgt atttaactag
    11281 gtacagattg tttataaagg ggagtatcaa aagtgctaat atataacctc ccctttcatg
    11341 tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta tattggtaaa
    11401 tttagactat cttttattat attatatagc aaacataagt ttttttcaaa aggattttaa
    11461 tatttaatta atcttgagat tttaaatttt tataattttc taaagcacca ttccaattta
    11521 ctgcattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt aaatagtaag
    11581 catgctccca aacgtcaagc cctattatag gagttaggtt tttacttaca gggctatctt
    11641 gatttggagt agtcataata gataatttcc catctttagt agccacaagc caagcccaac
    11701 cagaaccaaa gacatctaaa gcagcttttt ggaactcttg cttaaatttt tcaaaagaac
    11761 caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt tctggtgtca
    11821 ttatatcaaa aaagaattta tgattataag ctccacctgc attgtttctt acagctgtgg
    11881 caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa taattataaa
    11941 gctcaggata tttctcaaga gcaacattta atttatcaac ataagcttga tagtgtttat
    12001 catgatgcaa tttcattgtt tctttatcta tataaggttc aagtgcatca tatgcataag
    12061 gtaatggttt aactttaaat ttgttgtttt caggtgtaaa agcaaatgaa gttatgcact
    12121 gtgaaattat aaataaagac ataataactg gtattaatat ttttttcttc ataaaaatca
    12181 cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag acaatttata
    12241 agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag ccaaaactat
    12301 gaaatataga ataagactaa aatgcagaaa ggaattttaa ttatatggac ggcaatattt
    12361 caatttatta taaaggtgat atatctaaaa aagaaaatat taaatttaaa ataaaagaat
    12421 ctctaaataa tataaataat acaagagttt ctagtagaat agagtataaa agtgaggcaa
    12481 aaatttttga ttttgaaaga tttaatgtaa ttgatgttat ttatggaaac aaaccatttg
    12541 aaaaatatgg aaaagttatt gtttttaatg gaaatatata taacaaccat gaaataaaag
    12601 aagaattaat taaaagaggg cacagtttta ctacaggtga tgatattgaa gtcttattgg
    12661 catcttatat agaatttggt aagaattgtg tacataagat taagggaatg ttcaacttta
    12721 taatctatga tagagaaaac gaaagtatat ttggagcaag agatttattt gggataaaac
    12781 cactttatta tataaataag gaaagtgcaa taattttttc ctcagaatat aagtttatac
    12841 ttgaatatat gaaaaattta aatataaatg aaagaagctt acaaagttat ttttcatttc
    12901 agtatgtact tcctgaagat actatgatac aaggaataag gcttatacca gcaggtcatt
    12961 attttagggt agaaaatggc atattatctt taaagagata taataaactt gaatttagaa
    13021 gtagtacaaa atttttttat actaaaaatc acttaggtaa tagagatgtg gataaggaag
    13081 aagtaagaaa tattgtagta gattcaataa gaaatcatat ggaagagcat aaagaaattg
    13141 gaacatttct gtctggtgga atagattcat ctattataac tactgtggct tcacaaatta
    13201 atccaaatat aaaatctttt tctgcaggct ttagtgttaa aggatatagt gaattggaag
    13261 tagcaaagaa aacagctgat aaattaggta tagaaaatat ccagattaat ataacgcaag
    13321 atgaatatat aaaagcatta ccgaatgtaa tttattcttt ggatgaccct atagcagacc
    13381 cttcagaagt aggtctttat ttcttaatta aagaggcagg taaacatgtt aaagtagcat
    13441 tgtctggaga aggagcagat gaattatttg gaggatataa tatatataaa gagtatagta
    13501 ctatgaaatc agttgtcaac tcgccgactt atattaaagg tatattagga agagtttcag
    13561 aacttatgcc aaacataaaa ggaagaaact atctttatag agctacaaca ccattagaaa
    13621 aaagatatat aggaaatgca aaagtttttg aaaatagcga agtaaaaaga ttctttttta
    13681 agtataagga aaagaatata tatgaatacc tgttgtctaa tttgtataga gatgcacaaa
    13741 aaaataatta cgattatata agtaaaatgc aacatataga tgtgaataca tggcttcaag
    13801 gtgatatact tcaaaaaatt agcaaacttt ctacagctga gcaggttgaa cttagagttc
    13861 cttttttata taaagatgta tttgatgtag caaaaaattt aagaatggag caaaaaataa
    13921 acaagaataa tacaaaagtt ttacttagag aggcatttag agaaatagtc ccagaacatg
    13981 ttgttcaaag aaaaaaatta ggatttccaa ctccaataag agtttggtta aaagattctc
    14041 tgggggggat tgtaaaggaa actatctcta attcaaatgt agacgaattt atagataaaa
    14101 aatatgtaat aaaactttta gatatgcatc ttaaagggca tagagataat tcgagaaaaa
    14161 tatggactat atttacattt tgtctatggc atcaattgtt tattgagcat aaaaatgtcg
    14221 agtattaatt atgttttcat attaatcaga gggcaaaaac atgtactgtt ttttccctct
    14281 tgattattat ggaatagtac aaatagaact ttgattgatt agtttactat ttcaataaaa
    14341 ttattggcaa atattttgac aagactactt tctacagcta aatttaagtt ttgtccatca
    14401 tcatatccag cagaaatcaa tcctagtaag tttccaaaca tatctaaaag tgctcctcct
    14461 gaactaccac tagagattgg agctgtaaat tgtatcattt gaaccgtttc aaaatcacga
    14521 aaagctgaga taattccatc tgaaactgta ttaaaaagac ctaaagggct tccaattgca
    14581 actatttttt gacctcttac aggtttttta ccgattttaa caggtattgg cttacatttt
    14641 ctatcaactt ttatcacagc taaatcataa cctgaatggt attttatgat ttggtaagat
    14701 gtgtaaactt tatcatcatt ttcaaatcta actaaaaatg aataaccatc attgactaca
    14761 tgaagattcg taagtatata accttcatta tttattacta ccccagaacc gcttttaaac
    14821 ggtttatttt ctttattgca cacaacaatc ataacaacag aagctgataa ctttgcaagt
    14881 tcttcatagg aaagttctac ttcctcacct tgtacgattt ttttagatat taaatttgtg
    14941 ttattaaacg tattttcaga gttaggttta ttcatagggt gggaagtctt attggtattt
    15001 tcattgtaat ttatatttgc aatatgcctt tcaaaaggta tttctaatat atttggagtt
    15061 ttcctagaaa gttcaaatat attagaaaac tttgaacatt caggatataa atcaagaata
    15121 tctttatttg gatttatata taaaatatca cacccaagtt gtgataaaaa atataagaaa
    15181 aaaagttctt gtcttttaat atttccaaaa tacaatatct ttggtgaaat attagtattc
    15241 accttgttat aaaataattt aggtagaaaa tattctatcc aacacaaaag tttaactgca
    15301 aagtttttga tgatagaggg tgtacaattt ggcatactca tggaaaataa atctaaagta
    15361 tttttaaatg caatcttttt agtccaattt aaagtatcat tttctatttt acatgggaag
    15421 ttgatattat ataaatccca actgttaaat ttagcactat cataaatatt aaaaatttta
    15481 agcatcttat ctgtttgttc tttgtcaaaa tttatgttta gactgcttaa tctaatatag
    15541 ggaattatag gattattaaa aaaataagta tctatatttt taattttttc tatgtattta
    15601 tcaattgaat catcaacacc tatatatctt gtaaagtaga cttctttaat atatgaagaa
    15661 ctcttatttt gataggtagt attagacata aattcaatta gaggttcatt tgattttttt
    15721 attgaaatct ttagtggttt aatagtacaa atcatatttt ttctcctata ataagatgat
    15781 ataatctatt ataaaacaac ttaaaacaat atagtacaat aattttgtag tttcaaaata
    15841 aaatatgtac ttgtttatat aaatgatata taattacata ttaaacatag cttttataca
    15901 tttaataaag tatgtaaaat ctatgtaaaa agtaagaaat ataaacattt ttttaattat
    15961 attttaaaaa tatcaagcaa gttttcttca caaatgaata aaaaatgtta taatatgatt
    16021 aaagaaaaag ataaataatt agcaagattt gtttagctaa aattaacaag ggagcgataa
    16081 attatgggta taacattatc aaaaggccaa aaggttgatt taactaaagg aaatccaggt
    16141 cttaaaaata ttttagtagg tttaggatgg gatactaaca agtatgatgg tggatttgac
    16201 tttgatttag atacagcagc atttttaaca ggagcaagtg gaagtgttac taatgatgga
    16261 gattttgtat tttacaacaa tttaaaacat acatctggag cagttgagca tttaggagat
    16321 aacagaactg gcgaaggtga tggagatgat gaacaaatag ttgttgattt atctaagatt
    16381 cctggagaaa taagtaagat ttcttttact gttacaattc atgatgctac agaaagaaga
    16441 caaaattttg gtcaagtaag taattcttat ataagaatag tagataaaga cacaaatgaa
    16501 gagttaataa agtatgaatt aggagaagat tttagtatag aaacagctat agtagtagct
    16561 gaaatatata agcacaatgg agaatggaag tttaatgcac taggttctgg ttttgaaggt
    16621 ggtcttgctg cattatgtgg aaactttgga ataaacttat aatttcaact ataataataa
    16681 actaaagggg gatattttcc atggctatag tattaaaaaa aggacaaaaa atcgatttga
    16741 ctaagggaaa tccagggctt aaaaatataa aacttggact aggatgggat acaaattcat
    16801 ttgatagtgg ctatgattat gatttagatg taagtgtttt catggttgga gaatctcaaa
    16861 gagttgaaaa agatgaagat tttatattct acaataactt aaaacatcca tctggagcag
    16921 ttgaacactt aggtgataat agaactggtg aaggtgatgg agatgatgag gaaatattgg
    16981 tgaatttaga ggcaatgcca aagcatatac aaaagatagc tgtaacagtt acaatatatg
    17041 aggctgctga aagaagacaa aattttggac aggtaagcaa ctcatatata agagtattaa
    17101 attctgaaaa tgatgaagaa atattaagat atgacttagg tgaagaattt agtatagaaa
    17161 ctgcaattac ggtatgtgag atatataagt ataatggaga atggaagttt agtgcagttg
    17221 gagcaggatt tgaaggtggc ttagaagctc tttgtagaaa ctatggctta aatgtttaat
    17281 ttaagtaata taatatatta aatataaata acctatacaa ataatgtata ggttatatta
    17341 tataaaattt tgtggaggtt tagtatgtcg attaatttat caaaaggtga taaaatagat
    17401 ttaaaaaaat ctaatccggg actgagtaac atacttgtag gtctaggatg ggaccctgtg
    17461 caacaatctg gtggaggctt ttttaaatcg ttgtttggtg gaggacaagc tgatatagat
    17521 tgtgatgcat ctgtatttat gcttaatcaa gaaggtaaat taagtggaat aaaagattta
    17581 atttattttg gaaatctaaa aagtgcctgt aagtcagttt tacatacagg agacaatcta
    17641 actggtgagg gtgcaggtga tgatgaacaa attctagtta atttggataa agttccatca
    17701 aatattcata aattattatt tgtagtaaat atatacaatt gtgtggatag aaaacaacac
    17761 tttggaatga tagaaaatgc ctatataaga gttgaagacc aaggtaataa gaaagagata
    17821 gcaaaatata atctatctga taattattct gaaaaaacta ctcttatagt aggagctata
    17881 tatagaaaag atggcagttg gcaatttaaa gcaattggtg aaggaacaaa agatgcgggt
    17941 cttaaagaag taatgcaaaa tttagacagg attgagtgtg catatggaat ttaataatga
    18001 tatcaaatat tataatgtag ataaagaaga agttacaaaa gacttatctg ttaatcctga
    18061 aaaaggttta tcagaatcag aagttaagac tagaagagaa aagtatggtt tgaatgaatt
    18121 tactccaaaa gaagagggta gtttttggga tgacttaaag gaaagtttga gtgaaccaat
    18181 gatagttatc ttgattattg cagcagtagt aagtgcagta attggggaaa ctcatgatgc
    18241 aataggtatt gtaggtgcta tagcaatagg tatagcaata ggtatgatta cagaaggtcg
    18301 ttctaagaaa gcagcagaag cgctttctaa gttgactgaa aacatagaag taaaagtatt
    18361 gagagatggg gaagtacatc aaatttctaa gagtgaattg gtaccaggtg atatagtata
    18421 tattgaaact ggtgacatgg tacctgctga tggtagactt atagaaagta taaaccttaa
    18481 aattagagaa gatatgttaa caggagaatc tgatgatgta tctaaaaagt gtgatgtagt
    18541 agtttctatg gaagagatag aatctaaagg agcagtagta gtacaagagc caatacctgc
    18601 aaaacagata aatatggtgt ttggtggtac acttgtagct tatggtagag gagctctagt
    18661 tgtaacttca attggagata atagtgaaat gggtaaaatt gctcaaaacc tatcagaaac
    18721 agatgagcaa actccacttc agataaaact tggaaattta ggtggcttga tagccaaggt
    18781 ttctagtgca gtagcaggat tattgtttat atttatggtt ttccaaatgg taagtaagaa
    18841 tgtattaaat gtagatatgt ctggaatatt accattttta gaatcaatag acccagttaa
    18901 aacagcgttt acagtatgtg ttgcgttgat agttgcagca gtaccagagg gtcttccaac
    18961 tatgataaat atgacacttg caataacaat gcaaaaaatg gctaaaataa atgcattggt
    19021 tactaaaaaa gaagcttgtg aaacgatagg ttctgtttct gtgatatgtt cagataaaac
    19081 tgggacatta actgaaaata gaatgactgt agaagttgca tatgttgatg gaagatatat
    19141 tgaaagttca gaagaggaat taaatagtta ttttgaagaa aactgtatga taaactctac
    19201 agctgatgta gagcacaatg atggtgatat taagtattta ggaagtgcta ctgaatgtgc
    19261 attgctttta tattacaaaa acgtagatta tagacaagct agaaaaaatt ctaatatagt
    19321 agctcaaaat ccttttactt cagattcaaa gagaatgact tctgttatag gtcaagataa
    19381 tcatcatgta ttattatcaa aaggagcacc agaagtctta cttgagttat gttcacatat
    19441 tcaaagagga aaagacatag ttccattaac tgaaaatata aaacatgaga ttttagaaga
    19501 aataaagaaa ttgcaaataa aatcaatgag aactttaggg tttgcatata aagaaatctc
    19561 acaagctgaa gaagaagcag cagtaactgc cgaaagtgat gctatgaatg taagtgcaat
    19621 ggaaaataat ttagtattta gtggttttgt tggcataaga gacccactta gaaaagatgt
    19681 tatagagtct gtaaatacag caaataaagc tggtgtttct gtaaaaatgc ttacagggga
    19741 taatataaat acagcaagag ctataggtga agagttaggt ctattaaaaa ataatatgag
    19801 ggtggttgaa gcttcatata tagatacgtt agatgatgaa gagttaaaag aagagataca
    19861 aagtatttca atcgtggcaa gaagtaaacc agatagtaaa atgagaatag tttcagctct
    19921 acaaaagagc ggagatgttg ttgcagtaac gggtgatggt ataaatgatg ctccagcact
    19981 ttcaaaagca gatgtcggta tagcaatggg tatatctggt acagaggtat ctaaaaacgc
    20041 agcggacata attttaactg atgatagttt tagtaccatt gtaaaaggta ttaaatgggg
    20101 tagaggaatt tatgataact tccaaagatt cgttcaattc caattgactg taaatgtaat
    20161 tgcattttta gtggctataa tatctcaagt tatgggacaa gagatgccat ttactacaat
    20221 acaattatta tgggtaaaca taatcatgga tggaccacca gcactagcat taggtctaga
    20281 accagttaga gaccatgtat taaatagaaa acctgttgat agaaaagcca atataatttc
    20341 taagtcaatg gtgtatacaa tagtattaaa tgcattctat ataacagcaa tactaatgct
    20401 acaatctaca tttaatttct taggagttga cgaagctcat aagggaacag taatgtttgc
    20461 attatttgcc tttagtgcac tgtttaatgc gtttaactgt agagaattta atgcagatag
    20521 tattttccct aattttacac ataacaaatt agcactgcaa ataatagtat tgacaggaat
    20581 tgcacaagta atatttactc agttattcca agatttcttt aactctgtag caatggattt
    20641 tatgacatgg gtaaaagttc tatgtgtagc agcaagtgta attgtggtta atgaagttgt
    20701 aaaatgtata ataagactgg taaaaccaaa aaagactgct taaaacaaat tttttagaag
    20761 agaacagact gactcaaaat atgaattttg ggtcagttct gaataaacat ttaaattggg
    20821 aggatagtta tgggtgactc aaaggtattt gaaaaaatat tctccagcca atcagataga
    20881 ggaaattata ctccttcaaa gggatatcta agttatttta tttcatatat tggtttagaa
    20941 gatgaagttt tatacaatct cgagatattt aagacaaaac aaaatattga tagcaaaaaa
    21001 gatattgctt tatttactga tgttatagca aatcctagtg attttgatat tataaattat
    21061 tttaaaaatg gacttcaaaa atatagaact agtatggaag atgtagatat aaatatttta
    21121 ggatttgaag agattgatta taaaataaag caagcaatgg ataaagtgtt aaaagaggaa
    21181 gaaaaagaat ttactaatga tagagttaag caaaatttta tagtgaaaat aatggcatgg
    21241 ataaaaattt atatcggtgc tttagatata aataaaaatg aagctccaaa agtaatattt
    21301 tatggagata taaaaaaaca tgaagtttat ttactcttaa tattgtactt ggcaggtttt
    21361 gatgttttat atcttaatcc aaattcaaag agtaatatag atattttaaa atcagaaaga
    21421 tacaatgtag aatttgaaga agccaacata atagaagaaa aaacttcttt tgaagaaagg
    21481 gttattttag gtgaaaaaat agataaaagt tctgtaaaaa aagcttttac tgttggggca
    21541 gaagcatcaa aacgtataag tgaggaattg ttaaatgatg caggatttat aaaaccttgg
    21601 caacttcaag atagaaaaat aaaaaatcta cttctaagtt caaccgttga tgaaatatca
    21661 atatactgga atcagccact taaattaaga ccaggattta attttaatga tgctattgta
    21721 gaagctccaa attttctttc taagattaat ggaatatata atgataagaa tgaatatatt
    21781 aagtttttag atttattaag agattcggaa agttcaacgt ttattgaatt taatggagat
    21841 gtagatagat tttcaaaagc ttttacaaga gaagctttta gtttatcctt tttattggat
    21901 tcaaaaggtg taatagataa aaactctgtt ttaaataata aagattattc catatcaaca
    21961 ctagcattaa atcaacaaat tatgatttta gaaaaagtgg aagagttatt agaaggaagt
    22021 atgtttttga atggtttaag tggagaagac aagataaaag gtctatttac agtacttcac
    22081 atggataaga agtttgttca catgatgaac aattttgatt actcacttat aaatccaaaa
    22141 ttgattatat atatgtataa gagtattata tttgataaag aaatagtttt tcttatgctt
    22201 ttacttagta agattggatt tgatattatt atcctgtgtc caggaggaga aaataatata
    22261 gagaatgtta taaataacca attgattgat gtacacagat tggataaaat ggtatatgac
    22321 cttaaattaa attcgcttga aaatgatata cctttactta aaaaaatttt tggaaagagg
    22381 agacgatttt agatggggat aaatataaat agtttttcaa aagataagaa ctctgtagat
    22441 gttactgaga atttgcccac agcagttcaa gaagaaaatt tcgatataat ggaatataca
    22501 aataataaaa aaaatgaatt gagaaagtct aaggaagttg aggcattgac ttctcttata
    22561 gaagtagaaa atccagacac gattttacag tttggtagaa aagcatctga aggagtagca
    22621 agagtttctg atagcctttt aaatacaata aaattaaata gaaatgaaga aaattctaaa
    22681 atgttggttc atttaactaa aataatggac aagtttgatt tagatgattt tcaagagact
    22741 aaggaaccaa atttcgttca aaaacttttc aaaaaagcta ataacgccat tgaaatgatg
    22801 tttcaaaagt atgaaacatt aggaggagaa gttgaaaaaa ttcaaattga gcttgagcaa
    22861 tacgaaagag atatagcgct ttctaataag caaataggtg ctatgttaaa tgaaaacttt
    22921 gagttttata atgaacttca aaaatatatt gttgctggag aaatggcaat agaagaaatg
    22981 gataatgaga tactaccttt ctttaaacaa aaatcagaga ctagtggaga tcaaatggat
    23041 gttgttaatt atcaagaact attaaaagtt tatgatatgt taaatcaaag agtctatgat
    23101 ttaagaatag cagaaaatat agctattcaa acaataccta tgcttagagg tatgcaacat
    23161 aataattatg gtttaattag aaaaataaat agtgcatttg ttgtaacttt accagtattt
    23221 aaacaatgtt tatctcaagc tatattactt aaaaagcaag aattacaagc aaaatctcta
    23281 aaagcacttg atgacaaaac taatgaatta ttgcttagaa atgcacaaaa tgtaagttct
    23341 caaagtgcac aaatagctag aatggctgga acaagttctg ttcaaataga aacattggaa
    23401 aagatgtaca atactatcaa gtctggtata gatgaaacta tgagaataga agaaaacaat
    23461 agagctttaa ttaaagataa tacaaagaga ttggaagaat taaatacaac tataatttat
    23521 aataagtagt attatattaa gggctaattt atataaagtt ggccctttct atatatgagg
    23581 aggctagaca ttgaaatatt tcgattatat ctgtaaagat gatttggaga gaattttttt
    23641 gaaagagcca gaagacttta gtgctaagac tgaaaaagat gtactgaaat atgcactggg
    23701 agctttttta tacgttccag caactcaata taatatgatt tataagagta ttatagggga
    23761 tgttaaggga gttagaccat tagctatttg tttagaagat gctgttggag taaatgggga
    23821 gttagaggct atagaaaacc ttagattaat tttaaaaaat attagcaatg aaagtataac
    23881 taataaagat ggaataccac taatttttgt aagaataaaa gatgtggagc aactgttgag
    23941 aattaaagag attataatta aaaatagtca ttctataacc ggaatattaa ttcctaaagc
    24001 aaactcggaa ttaattgaaa attgtataga agctttagat tctatgaatc ttcaagatat
    24061 gtatgttatt ccaataatag agacaagaga atttatatat aatgaaaaaa aagaacttag
    24121 ttttattaat ttgtacaatg ctattttaag acataagtca agaatattaa gcattagagt
    24181 aggtataact gatatattag ggatgtatgg tataaggaga gataaaaact tttctatata
    24241 taataatttg atttgttctt catttatact agatataatc acatatcttc aaagaccaga
    24301 gctagatata cctataagtg gtggagtgtc agaatttttt gatatgaaaa ataaggacat
    24361 aagaaataag tatatagaag aaatattatt agataaatat catggattaa ttggaaagac
    24421 tgtaattcat ccaatgcaaa ttcaaattgt acaagcgtta tctacagtat catatgaaga
    24481 ttttactgat gccttggata tattggatag tacagacagt aaatatggtg tgagtaaggg
    24541 tgtgttagga gagagaatga atgaaataaa tccacatttt ttatgggcta aaaaaacatt
    24601 gattctatct aaaatatatg gtgtattaaa tgaaggagta gactatgaag aattgcttaa
    24661 attttaattg tgagattgac attattgata atccattaaa tttagaacta aatgattttt
    24721 tagacatagg aataagaaat aatagcaaaa gacgtttttt gtttatctca aagaaacttg
    24781 gtaagcattt agcatgtaag ccaagtgaga tggataattt gggaaaatta atagctacaa
    24841 tttataatga aaaaaataag gaggaatcaa atggtactgt tatagctttt gctgaaactg
    24901 gtacagctgt tgggcatagt ttttttgatt atttatgtgg agattatgaa tttattcata
    24961 ctactagaga acagtttgac gagttagaaa atctggaatt tttagaagaa cattctcatg
    25021 caacagacca aaatttatac tttggtatgc ttaacaactt taaatttgga gatgagataa
    25081 tattggttga tgatgagatt accacagcca atacatgcat gaacataatt aggaagattc
    25141 aaagcatcta tcctaaaaag aaatacacta tatgttcaat actcaattgg gtaagtgatg
    25201 aaaatttaag taaagttact cgtttagaaa gagagctaga ttgtaagata gattttgtat
    25261 atttatttaa aggaaacttt aaattttata tagatgaaga tattatttca aattataacg
    25321 ataattatac tattactaaa ttagatacta ttttaagtga taaagtaaat ttagtagtaa
    25381 atcatattta tgttgattta gaagattaca ttggaaataa gaaatatgta aaatatacag
    25441 gaagatttgg aattaataga agagaacaat ttagattaaa agaaatcgtt aagagagaaa
    25501 gtaaaaaaat aactatagac aataaagaat ctttaaaaaa tgaaaaagaa aagattctat
    25561 ttttaggtac tgaagaattt atgtatatac ctatgctgtt tgcaaaagaa aaagaaaatc
    25621 aatgtgatgt atactatcat tcaacaacaa gaagtccaat tattaatatt gataagcata
    25681 attatcctat tagaagtaaa tttatgctaa agagttttta taatatggat attcaaaatt
    25741 atatttataa tatagataaa cagaattttt ctaaatgtta tttatttgta gagctaaata
    25801 aaagtgaaaa ttcttatcta gagtttattg atataattaa aaagacaagt ataaaagaat
    25861 taactatagt atgttgtagc tagagtgttt taacaggata aaatatatca cgattttaag
    25921 ataggagttg agtcatatga gagattttag tacgtattct aaagatgatg ttattttttt
    25981 attaaaagat atatcaaatt taattgaaga agaaggaaat aaagaaagag aattaaaaat
    26041 acaaaatggt agacattatt cagaaatgat accaatagag tatgaagtta gtgaagatta
    26101 tctgaattta tatcatgaga aactaagaga aaataaagat aagcttgcat tttctatagg
    26161 cgttatgtgt gaaaaaataa ttaaaaaaaa tggaaatgat gtagtactcg tttcacttgc
    26221 tagagcagga acacctattg gtattttggc aaaaagatat gtaaaaagca agtataatat
    26281 aaatttacct cactatacaa tctctataat aagagataag ggaatagata tgaatgcaat
    26341 tgaatatata gtaaagaatc atccgagctc aaagattcaa tttttagatg gatggactgg
    26401 taaaggaact atatcaaaag aacttgaaaa agcatgtgat gagcttaatg ataaatttaa
    26461 aaaacatttt gactcaacac ttgctgtatt agctgaccct gctggatatt caggacttta
    26521 tggaattaga gaagatttct taataccaag tgcatgttta aattcaaccg tttctggtct
    26581 agtaagcaga actgtactaa gagaggattt aattggtaaa aatgacttcc atggagctaa
    26641 gttttataga catttaaaag ataaagatga gtctatgaac tatattgaaa ctatagaaga
    26701 atgttttaaa aatcaattta agaacatatc tgatgaagtt gaaaactggg aaagtgatat
    26761 tataacaaga gatggatact ttgatgtttt aaatataaaa gaaaagtata acataacaga
    26821 tattaacttt atcaaaccag gtgtaggaga aacgacaagg gttttactta gaagagttcc
    26881 gtataagatt cttgttaaag acttaaatga taaatcttta gaccatatat tcgtattagc
    26941 taaggagaaa aatgttgaag ttgaacaaat ggatttaaaa gcctataaat gttgtggaat
    27001 aataaaaaat atgaaagatg tttaggaaat atattagaca ggagaatatt gaatgattgt
    27061 tttttcagat ttagacagga gtatcattta ctccaataaa tttttaagtg ctgatagtaa
    27121 atatgctaat atagaaattt atagggaaaa agaaatatct tatatatctt tagatactat
    27181 aaatttaata aagcaaatac aatattatgg tatgtttata cctacaacta ctagaacagt
    27241 ggagcaattt aagcgcatag agtttaataa atatgggatt tattttcctt ggagtataac
    27301 ttcaaatgga ggagttatac ttaaagataa tgaaatattg aaatcatgga gtgaaaaaat
    27361 agataaacta aaatctgact atgagcccat tgaaagcatg atttataaat ttaaagacta
    27421 tttgaatgta gatggaataa ctaattttaa agttgcagaa gatacatttt tttatatagt
    27481 tgttgatttc tcaaaattta atttagaatc aattaaagaa tatacaaatg tattggaatc
    27541 aaaaaattgg aagttttatg tgagtggcag aaaaatatat tttataccaa aagaaatttc
    27601 aaaagaaaat gctataaaat acttgaccaa agaattagga atagaatatt tttatgcaat
    27661 tggcgactct attatggact atggtatgct taatatctca aataaagctt atctattgaa
    27721 gcatggtgat ataaataaaa atgaaataga aaattcattt ttatcaagtt cttttaatgg
    27781 aatgagtgga actgaagaga tactatccaa cattttagat gaaaactgtc tacttaatat
    27841 ataatgactg atatataaat aataagctag aaaaatctga aataaattag aataaagttt
    27901 atcatactaa tttatttcag atttttatca atttatattt aagtaagaac tcaatatgtt
    27961 aaaatgaagg tggtgtcatt gcccagactg agatacatac atcatcatca taattttcat
    28021 atacatgtgg gatagtactg ttaaaataaa aactatctcc ttcttccaat agatattcct
    28081 tatttccaag tgttatcttc attttacctt ttattatata gccacattct tctccttcat
    28141 gtgttacaaa ttcactgttt ttttgtgtat gaccatctaa agtaacaagt ataaattcta
    28201 tttttttccc agataaatta ggaacaagaa gttcgtaaaa ttttgtagaa tcattagtta
    28261 ctattttttt tcgattattt ttctttacta ctatatcaga gtcctctctt ccaatctctt
    28321 caaaaaaata acctatattt atatcgaggg cttttgatat tttccacatt gctacaatag
    28381 atggaacaac catattacgc tcaatttgac ttattaagcc tgtacttaaa tctgaatttt
    28441 ttgctaaagt agagatactt atatttttag attttctaag agatctaatt ttgcttccga
    28501 catctatatt cattagatac aaacctcctc agacatgatt ataacatata atttataaag
    28561 attaataaaa taaaaaaagt tttataatac atgtattttt tctgttatat tgaattttct
    28621 gaaaagatgc attataatag tattaatatt caatatattg aatattgata tcgatatttt
    28681 aatttaatga aatggaggta gttaagatga agagttttgt aagtcctgat aatatttggg
    28741 tattatgggc agttgtaact ggatgggcag catttagtat ttatttggaa caaaagtaca
    28801 attgggcatc aaaagtgtct ggagcaataa tagctcttgt aggagcaatg ttattatcaa
    28861 atctaaatat tataccagta gagtctgttg tatatgacca agtatgggga tatgttgttc
    28921 ctttagccat agctttattg ttatatcaat gtaacattaa aaagatatgg aaagaaagtg
    28981 gaagattgct cattatattt cttgtaggtt ctgtgggaac tgtacttgga gctatgattg
    29041 gatttttagc attaaaaaat gtagtaccag atttaaatat tgttgcagct atgatgacag
    29101 gttcttatat aggtggaaat gtaaactttg ccgctatgtc aggggcattt gatgcgccag
    29161 gagaattagt atcagcaaca gttgtagcag ataatctttt aatggcatta tatttctttg
    29221 tcttaatagc tataccatca attggatttt ttagaaaaca ttttaaacat ccacatgtag
    29281 atgaaatgga aagtataggt gtaactgaag gagaaacagt agcagcaaat tattggggaa
    29341 gaaaagaaat atctctaaaa gatatagcaa tagccattgg tagtgccttt ataattgttg
    29401 ctgtatctgt agaactatca acttggttca aagctataat accattatca aatccttttt
    29461 tagcaatgtt aaatacttta tttggaaatc aatatctaat aataactact ttgactatgt
    29521 tgtttgctac atttatgcct aatttctttg gtgacataaa aggagcacag gagttgggta
    29581 catttttaat atatatattc tttgttgtag taggcgttcc tgcttcaata acattaataa
    29641 ttcaaaaatc accattacta cttttatact gtggaataat ggtactaata aacatgctag
    29701 ttacatttat agttgcaaaa atatttaagt ttagtttaga agaagctatt cttgcatcta
    29761 atgcaaatat tggtggacct acaacagccg cagccatggc gatatcaaaa ggatggtcta
    29821 agctagtagg gccaatactt atagttggta catttggata catagttggt aattattttg
    29881 gtcttttagt aggaaacatt ttgatataat tttacgtgaa aaaaagttgt tttttagaaa
    29941 gatttttatt taattggagg ttgttatgat tttcgatgga cattcagata cttgggcaga
    30001 tgtaacaata agaaggctta atggggaaaa agatgtattt agaagaatcc atcttgataa
    30061 ttttaaaaga gcaaatatag aaggagctat ttttgtaata tggatagacc cgccatatga
    30121 taaagagcct gaaaaaagag ttaaacaaat cataagctct ataaaagatg aaattgaaga
    30181 tatgaaagat gttgtaaata tagtaaaaaa atattcagat atagataaag gtataagtga
    30241 acataaaata aatattttaa ttggtcttga aggattaagc catattggaa gtaatataga
    30301 ttcaatagat tatttttata aagaagttgg tgcaagacat gcatcattaa cttggaatga
    30361 acagaatgaa cttgctacag gttgtttagg agatgaaaat aggggtttaa ctgaaatagg
    30421 taaaaaagca gtccataaaa tggaaaattt gggcatgata gtagatgtgt cacatttaaa
    30481 tgaaaaatca ttttgggatt taatgtctat tgcaagtaag ccagttatag cttctcattc
    30541 taatgctaag agtttatgtg atgttaaaag aaatcttaca gataatcaat taaaagaaat
    30601 tgcaaataca ggtggattag ttggaataaa tagttttaga ggatttacta atagtaatcc
    30661 taagaagcaa gatttaatac atttggttga ccatatagat tatatggtaa atcttatagg
    30721 tatagaacat gtatcttttg gttttgattt tagtgattac ttggggaaag agaccatagg
    30781 ttctttcact ggaaactcta gtatgccaag tgtagatggt cttgaaagca cacatacagc
    30841 acataacata gtagtagagc ttgaaaatag aggttataaa aaaagagata tagatttaat
    30901 ctctagtggt aatttttata gactcttt
//
LOCUS       DBGJFK010000044        28959 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.044, whole genome shotgun sequence.
ACCESSION   DBGJFK010000044 DBGJFK010000000
VERSION     DBGJFK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28959
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.044"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(39..212)
                     /locus_tag="ACOIAP_002295"
     CDS             complement(39..212)
                     /locus_tag="ACOIAP_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HGZ2639178.1"
                     /translation="MSNEKYIIKNILLKTLRKLRNNNSYGYDISEFKDMYELFIENED
                     VFVSIRKLAKYDF"
     gene            complement(289..1158)
                     /locus_tag="ACOIAP_002296"
     CDS             complement(289..1158)
                     /locus_tag="ACOIAP_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HGZ2639179.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRAGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDELDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIETVKC"
     gene            complement(1178..3094)
                     /locus_tag="ACOIAP_002297"
     CDS             complement(1178..3094)
                     /locus_tag="ACOIAP_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGZ2639180.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKADELIQRCIDG
                     KVAIRKGNSSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDERKNKSAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMVGVLDKSGVLLDKNKFKEEILKREEISSTGFGMGIAIPHAKTDAVKIPRVAVGV
                     SKEGFDFESEDGSLVHIIFMIAATDNGDNLHLKTLSQLSAKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(3097..4017)
                     /locus_tag="ACOIAP_002298"
     CDS             complement(3097..4017)
                     /locus_tag="ACOIAP_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HGZ2639181.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFNVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLEKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGESIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(4119..4871)
                     /locus_tag="ACOIAP_002299"
     CDS             complement(4119..4871)
                     /locus_tag="ACOIAP_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGZ2639182.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINQSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(5263..5538)
                     /locus_tag="ACOIAP_002300"
                     /pseudo
     CDS             complement(5263..5538)
                     /locus_tag="ACOIAP_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898145.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(5925..6695)
                     /locus_tag="ACOIAP_002301"
     CDS             complement(5925..6695)
                     /locus_tag="ACOIAP_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HGZ2639183.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDLCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLMGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEEVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLVQ
                     ERVYEHAMLCDKEVKMWLRRNNIELVDFKDIFKANNYI"
     gene            complement(6697..8145)
                     /locus_tag="ACOIAP_002302"
     CDS             complement(6697..8145)
                     /locus_tag="ACOIAP_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGZ2639184.1"
                     /translation="MKRFLNKMMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVP
                     AISNISTIVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNA
                     GVFGGIIVGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLAPVVALILSYIFSLLWIY
                     PQAAMNQFGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTPTGEVI
                     RGEIPRFMAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKRKQEVKGAMTAGALT
                     SFMATVTEPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSF
                     SYGDKAWLVIPIGIIFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLS
                     HGNFSYMAKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLS
                     NTSVQIIIGTDVVKVKDEMEIQLDELRKQADA"
     gene            8515..9237
                     /locus_tag="ACOIAP_002303"
     CDS             8515..9237
                     /locus_tag="ACOIAP_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2639185.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNAEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKIGSEVYYLHRLRYIDNVPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            9434..11101
                     /locus_tag="ACOIAP_002304"
     CDS             9434..11101
                     /locus_tag="ACOIAP_002304"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGZ2639186.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLSSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEELLKEAHKRDLKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDKTTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGVKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALIILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSHSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNILVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDTIENEMEIKPYESIMIYCK"
     gene            complement(11196..12515)
                     /locus_tag="ACOIAP_002305"
     CDS             complement(11196..12515)
                     /locus_tag="ACOIAP_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGZ2639187.1"
                     /translation="MEKGIKLGFWSIVLLGINAIVGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGNFIGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKQLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSSSSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLVGSTTPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYPKKYNNVEVK"
     gene            complement(12553..13305)
                     /locus_tag="ACOIAP_002306"
     CDS             complement(12553..13305)
                     /locus_tag="ACOIAP_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGZ2639188.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CEAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDINPLIWKEEPHNKLGAISPKRDVF
                     DMKLLKYALDMKKPVLGICRGEQIINVAEGGSLYQDLSLIEGAYIKHNQQHLSNIPTH
                     TALIKEDTKLYEILGEKEILVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTKDYDNMKKIFMAIVKEASKEK"
     gene            complement(13549..15558)
                     /locus_tag="ACOIAP_002307"
     CDS             complement(13549..15558)
                     /locus_tag="ACOIAP_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2639189.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGIAMISDKGNVIICNNSLSNILDIQGNIIGKNIDELENENIKKIFRLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSLKMERTKELGMKIAKSDYTVLITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKEDRFRADLYYRINVLPVNIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     SDLPHNLLNITEDFSKEISILKDRTSLEKVKLVMGCLKNANNLNKNIGRNGIVNSINE
                     LGYSITEGEVRGILNILKELDLIICESGRRGSELNRRGKNILNSM"
     gene            complement(15994..17427)
                     /locus_tag="ACOIAP_002308"
     CDS             complement(15994..17427)
                     /locus_tag="ACOIAP_002308"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGZ2639190.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGTSCSDMCTGGSQTVSK
                     RITRTIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEVPFAITEKYNGWASREVIDLYMNYCEAIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFISQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPNDVVKTQEDNRVMNYFCGDVQVRG
                     EYPTYMNRYFRENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSESKESNTSGNI
                     LGGVKNPYLESSEWGWQIDPKGLRYALNEIYDRYRIPMMVVENGLGAYDKKEPDGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFNWYKQVIESNGERL"
     gene            complement(17443..18867)
                     /locus_tag="ACOIAP_002309"
     CDS             complement(17443..18867)
                     /locus_tag="ACOIAP_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGZ2639191.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEGGRGLANVDVIPQGKDRFPV
                     LTGKMKMFECDEEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGIE
                     EVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKDKIKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMIAAGNTYANTCNPLDVWKSIEKDRENYFFIDVQSRGEYPAY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPEVNILTEGNVFESL
                     KNPYLDASEWGWQIDPLGLRITINSLYDRYQKPLFIVENGLGAVDNPDETGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFDWYKKVIESNGKEL"
     gene            complement(18954..20870)
                     /locus_tag="ACOIAP_002310"
     CDS             complement(18954..20870)
                     /locus_tag="ACOIAP_002310"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGZ2639192.1"
                     /translation="MRKYEQLSKEIIENVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSTGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSGSDSPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVFLASKLEKMFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKMKELCIPAIISGICGVTEPAIYGITL
                     PRKKPFIYSCVGGAVAGAVMGVMNVKSYVMGGLGIFGIPNYINPTTGDMTGVYATTIS
                     IIVAIVVGFVLTFFLWKDDTIVEISKDNNSKGAVEKNKREVIYSPIKGEVKALEHMQD
                     AAFSTGVLGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLLTFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHISNSQELITVLA"
     gene            complement(20944..21804)
                     /gene="licT"
                     /locus_tag="ACOIAP_002311"
     CDS             complement(20944..21804)
                     /gene="licT"
                     /locus_tag="ACOIAP_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGZ2639193.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGDHISKDKI
                     DKIFKLSDPNICDKFKELIADIPMKYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVNVKNVLLWDIKRFYKNEFNIGLKALDYIEKKFEIRLPEDEAGFIALHI
                     VNAQMDQSIKIIYDITQIIQEIANVVKYHYRIVFDEDSVYYHRFITHLKYFAERVVSN
                     NLHENNEDDLLKVIKVKYKNAYKCIEKLDEFIHKKYNYNLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(22157..23344)
                     /locus_tag="ACOIAP_002312"
     CDS             complement(22157..23344)
                     /locus_tag="ACOIAP_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2639194.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMEEYGFDTIYPYCNMETAFRAELGNNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDINPMVYVHEKEFLSYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(23358..24749)
                     /locus_tag="ACOIAP_002313"
     CDS             complement(23358..24749)
                     /locus_tag="ACOIAP_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGZ2639195.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKRFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQITPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDSNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFIIPLMVALTVL
                     VMVFLTIGLYLGF"
     regulatory      complement(24894..25073)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(25345..26997)
                     /locus_tag="ACOIAP_002314"
     CDS             complement(25345..26997)
                     /locus_tag="ACOIAP_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGZ2639196.1"
                     /translation="MKDKLQVLSGAMMIPVILLVVAGVFIGLGSAFANMENVYALGLS
                     GIIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKKEKGWGALGGIVLFIGM
                     HTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGSFLGIFSYDCSIFGAII
                     AGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLGTAMYFIWPPVGLALSK
                     LGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVGGTMEVGGAIYEGVNNI
                     RLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLADNVNKKKAISILIPAIV
                     TAMLVGVTEPIEYTFLFVAPLLYFLAYVPLAGLTYVFTEMFNVSIMGESFRNMFPNLL
                     QPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSEEVKLYSKKEYREKQSV
                     DAGKTVYNNAVGDEVDDKDTELVHSIIEGLGGSSNIKNVTNCATRLRVELNSIDGFYD
                     DGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD"
     gene            complement(27017..28420)
                     /locus_tag="ACOIAP_002315"
     CDS             complement(27017..28420)
                     /locus_tag="ACOIAP_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2639197.1"
                     /translation="MIVNKELIIDYLKSNQENIIKDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIKIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNNKKDLVESLAYYTEIEEVEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLERIKGLNDKGVIIKDILNSYFTDDNHGKKIGIYKEDVDMGVSTICIMS
                     IFLDKNELNMKIDFRYPKGISLEFITNRINEIGKKENLIIDIYKNLKLLYVEPDSELI
                     NKLSSAYKQGFEKEAELFTKGAASYARVLENGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
BASE COUNT         9340 a         5323 c         3175 g        11121 t
ORIGIN      
        1 atagaatata cattttttat tttagttaaa atctctctct aaaaatcata ttttgcaagt
       61 tttcttatac taacaaatac atcctcattt tctataaaca actcatacat atctttaaac
      121 tctgatatat catatccata agagttatta tttcttaatt ttctaagcgt ttttaataat
      181 atattcttta ttatatattt ctcatttgac atcttaaata tacaaaataa agtaagatat
      241 ctactataga tatcttactt tattttcatt tataattata ttttattatt aacactttac
      301 tgtctctatt gcttttccta cacatccaca aacttccatt ctactcttaa caaaatcttt
      361 aactgactct aaaccttttt taccatattt cttagggtca attacctctg ggtcagaatt
      421 aagcacatcc ttaaccccat tactataagc aatccttaat tctgttgcat aattaacctt
      481 gcaaatccct ctttttatag attccttaat aacctcatct ggtattccag acccaccatg
      541 taatactaat ggaactgata caacctctct aatttcagat aatctatcta aatcaagctt
      601 tggctctccc ttatatagcc catgtgccgt acctattgct actgccaaag atgatacccc
      661 tgttctctct acaaactctt ttgcttctaa tgggtctgta tatgctccac catcaccacc
      721 atctaattcg tcttccttac ctccaacttt acctaattca gcttcaacag gtatatctga
      781 aggcatacat gcatctacaa cagatttaga tattgaaata ttatcttcgt aactttcatg
      841 agaaccatca atcataatag aagtatatcc agctctaagt gcctgcatag ctagtccaaa
      901 gcttgaacca tggtctaagt gcattgctac tggaacactt gccttctctg atgctacctt
      961 tacattcgct aaataataat ctagtcctgc atactttatt gttgaaggtg ttgtttgcaa
     1021 tattactggt gatttaagct cttcagcagc ctctattact gccataacca tctccatatt
     1081 ttcaacatta aatgcaccta ctgcataatg cccttcttgt gcatctaata atatttgttt
     1141 agttgtaact aatgccataa tctctcctcc tatatgttta tactgatttg atttcttcgt
     1201 tatttaattt tgatactatt tccctacttg tcttgctatt taataactca tttaaaaatt
     1261 cttcattcat taattttgca gataattgag ataatgtttt taagtgtaaa ttatcaccat
     1321 tgtctgtagc tgctatcata aatataatat gtaccaagct tccatcttct gattcaaagt
     1381 caaacccttc ttttgataca cccactgcta cacgtggtat ttttactgca tctgtttttg
     1441 catgtggtat cgctatcccc ataccaaaac ctgtagatga tatttcttct ctcttaagga
     1501 tttcttcttt aaacttattt ttatctaaaa gaacaccaga tttatcaagt actccaacca
     1561 tttcatcaat tacatctgtt ttattttttc ccttaacatc taaaattact gtttcttcgc
     1621 tatataaaga gatattatta gatacgtttt ccgattctgc acttttattt ttacgttcat
     1681 ctttagttgc atttgtattt tctatagtat ttttctcatt tactacttta ggtgtaacca
     1741 tcatataaag tacagcacct actaatgaac ctacaaatat acaccctacc cataaaagtg
     1801 gcttattgac taatcctaga accaaaaacc ctccatgtgg agctggtact tctattttca
     1861 ttatataagt taaaattgat gatattgatg atgcaatcat aagtactggc aacactttta
     1921 atggattttt tgctgcaaaa ggtattgccc cctctgttat atgagtacta cctagtatat
     1981 aattgattaa tcctgcggct ctatcttctt ctgtaaatct gtttttaaat aaagtggatg
     2041 ctattgctat taccaatggt ggtgttatac aagctgcaga tacacctgcc atgaataaat
     2101 aatttccctg tcctagaagc atagttccag ttacatatgc tgctttattt actggacctc
     2161 ccatatcaaa tgctgacata catcctatta ctattcccaa gattataggg cttgaatttt
     2221 gcaaccctga tagaaagttc atcatagcat tgttaagtgc tgagcatggt ccaccaagta
     2281 acaacatggc tacacccaca agacctacac ttacaatagg aattataaaa atagatttaa
     2341 gaccttctaa ttgtcttggt aattttctta acaaatgcac aaataattta actaagtaac
     2401 ctgctaaaaa tcctgatatg attccaccta aaaaacccga acctgtatcg aatgatatca
     2461 ttcctccaac aagtcctgcc aacataccag ctcttcccga tatagattga gctataaatg
     2521 ctgccaacac aggaaccatc aaattcatag aatatccacc aacagatttt aatgtagctg
     2581 ctatttgatt atattgttct gaatttgggt caaatgaata aatcccccat aaaaatgata
     2641 tagccgtcaa tactccacct gctactacta aaggtaacat gtgagataca ccattcatta
     2701 agtctttata taacttttga ccaaacgata aatttccttc ttctgcaatt ttactgcttg
     2761 atgagtttcc ttttctaata gctacttttc catcaataca cctttgtata agttcatcag
     2821 ctttatgtat accttctttg acaggtactt ctattactgg cttcccattg aatctgtcca
     2881 tatcaacatt tttatcacaa gcaactatta ttgcatctgc catttcgata tcttttgctg
     2941 ttaacttatt ttctacacct atggctccat tcgtttcaac ttttatatca caccctaatt
     3001 ccctagctga attttttaat gcttcttctg ccataaaagt atgagctatt ccagttggac
     3061 aacctgttac ccctagaatc attttctttc ccatttttat accacctttc tgactcttat
     3121 attttttata taatcttcca cattctccaa attacctata ccattacttt cagccacact
     3181 tgctcctgtt gctgctgacc tttttaatgc ttcttcaata tgttctggat tttccaacca
     3241 tatacttaaa aaagcagcta atgcagaatc accagcacat gcagagctga ctacggtaac
     3301 tggttgggca ctagcataat aaattgattc tccattataa aaataagaac ctttttctcc
     3361 taaagttagt aatatatttt gagcgccttt taaatgcagt aatttaagta catccttaat
     3421 atcttcttca tctcttacaa taattccaaa tatatctttg atttcttcat catttggttt
     3481 tatcaaatat ggattatact gtagtaactc ctttaatttt ggtgaactta tatcgagtat
     3541 tgtctttata cttttatttt tacaaatctt aaatatatcc tcataataat tatcatcaat
     3601 accaggaggc agacttccac ttattgataa ataacttata tcttctaatg actgtatctt
     3661 ctctagcata tctaattttt gtttttcgtt tacatacgac ccagagttta caaatttaaa
     3721 ttcatcactt ccatcattta aaaatatatt tatacgagtt gtatcttcta cccaagtagg
     3781 caatacatta aatcctctct tttcactttc ttcaactata tattttcctg aaaaacctcc
     3841 aaaaaatcct aatatcttag attctatacc ataatgacct agtacaaatg ttacatttaa
     3901 tccctttcca ttaggagaat atacagcatt tgatgtacga tttactaatt ttctctttat
     3961 cccattagta gatatattca tatctattgc aggattcgta gttaatgtat atatcattgt
     4021 cttccccctt gcttgtgctg tgtatgtttt cattataata aaaaagtcta tgaaaatctt
     4081 ttcacaaata gaaaatcgat tttcatagac ttttcaattt aattttcaga attattatat
     4141 ctgaccatat aatctatgat tatcctagat ataatataca agggcaatct agaggatact
     4201 tcatattcag aaattgatat atgttcatgt ttgtatccta caatatataa atctgaatac
     4261 tttataagtt ttgcactttc actacaacaa caagttataa ctttagctcc aactaaattg
     4321 gcattctgtg ctgattctac aagctctatg gtatttccat tcaatgaaaa tataattata
     4381 agttcgtctt tttttattga tttagatttt attttcatta tgttggggtc atttataaaa
     4441 acaacattaa aatcaagtaa ttgcagttta agactaaact cttttgctac atattcagta
     4501 agccctcttg ctaaaatata tatcttacta gattgattta tagtttttat tatattaatt
     4561 agtgtagtta aagatatttg ttctataact ctctgtgctt ctataaagga tttatttatt
     4621 atatctccca tattttgtat atcatcattt tcatctttta ctgttaatct atacctaagt
     4681 tcattgaatc catttaaacc acattttcta attgctcttg aaacagttgc tggagatgaa
     4741 tatgtttcat gagcaatctc tactatagat aattctggta atattgattc attttcattt
     4801 ataaatttaa ttatttcaag ttccgtcttc gttagatttt cagaattact tttgtttagc
     4861 tcaattatca tatgttatct ccccttatat aagttttatt tgtctaaatt taccgagtaa
     4921 tataatatat tacctcttaa ctatttattt ttatatacaa ttaagattta gtcaatgtct
     4981 atatatgtaa atttataata tcataatttt ttacttaaag tttattatgt tattttatag
     5041 cattttaaga taaaaaagaa ttgtaccgct actaaaatcc ggctgaaata caataaatat
     5101 tcctcatcct gatatgttta taattaaagg tataaatata aactttgcta tgaatcacat
     5161 aattaataaa tcattttatt tacaattata acccccctta taaaactata ttaataatat
     5221 atacagtatt tataaaggag gttatttata tttaaaaact atttactttt ctcttaattc
     5281 ttctccatta gttcttatta cattttgata ccaataaaaa ctatcttttt tataacgttc
     5341 tttgtttcca tttccattat tatctatatc cacatatata aatccatatc ttttttccat
     5401 ttcctgagat gaacaactta ctatatctat tggtgaccac atacaataag ctaatatttc
     5461 agttccatca gctatagctt cacctatttg ctctatatgt tttgataaat aatctatcct
     5521 gtaactatca tgaacttttc agatactcat aatctcggtt ttgataataa agtatacata
     5581 gttattacta ctttaccaat tagtgataga tatcctatac cctttgttta tgtaaatcct
     5641 tacctaaacg gaaagaatta tgacaatatc caaattaaat ttcttcatat tataaggtag
     5701 aaaaaatata cttattgtac aaaaccattt agaaatgtac tttagtgaat ctttatttat
     5761 gaaaaatatc tatctctttt tattatacat aaaaaatgtg tacttcctat attgataggg
     5821 atgattcaaa tttttatttt gatacatctc tatcaatatt cttttagaaa atacacattt
     5881 ttttaaatac ttatttttaa ttaaaacttt aagtaatcta ttctttatat ataattatta
     5941 gccttaaaaa tatctttaaa atcaaccaat tcaatattat ttcttcttaa ccacatttta
     6001 acttccttat cacatagcat tgcatgttca tatactcttt cttgaacaag agaagatgat
     6061 tttataagac tataatctat aaatcctgga tgagtaacca tcaatgttat atctttatct
     6121 aaatttatat acttttcttc aaataattta acaaaagatt tatttaactt ataaaaatca
     6181 ttctgaggat atttacttgg catactaata catgaatcta aataataggg acaacttggt
     6241 ataccatatt ctttagcagc atcacacatt gctgatattg atacctcttc ttctatacca
     6301 tgtatatcaa tatactcagg caacttactc atatacaact tgtaagtttc aatttgagca
     6361 caaacttctt catatacttc ttcataatta aaaacctctt tacccatcag taactgcgtt
     6421 cttcttattt tgctagaaac aaattttcca ccttcatcta acaaattctt tatcttaata
     6481 tgttctttgc aacaaggttc tcctattact aagttaacat gtaaaccaaa acataaatca
     6541 tcatttttta ccatttctat ggcttgtctt gaaaaaggca tattcaccat gattccggca
     6601 cttgtaacaa taccattctt ataagaagat attataccga gtgtaacacc ttctgaatat
     6661 cctatatcat ctgccctaac tactaatttc ttcattttat gcatctgcct gctttctcaa
     6721 ctcatcaagt tgtatttcca tctcatcctt tactttaaca acatccgttc ctatgattat
     6781 ttgaactgat gtattactca atttaattac ccctttagct cctgtttttt taatattatc
     6841 atcattcaaa atagtggcat ctttcacttc taaacgcaac cttgtcatac aattattaag
     6901 agtcactata ttttcataac caccacaatt tttaattatc tgcttagcca tatatgaaaa
     6961 attaccatga gaaagtttta aattcttttc tttttcacta actttatcac ctatctctat
     7021 ctcaacttca cgtcctggtg tttgtacatt atcttttatt attatatatt taaatgttac
     7081 ataatataat acaaagaata taattcctat aggtataact aaccatgctt tatctccata
     7141 actaaaactt aaaacataat caattatact tgctccatta aatgaaccca agcgagcacc
     7201 cagtaaatat agtacaactc cacctagacc agaataaaaa gaatgaatta tatataactt
     7261 tggagatgca aataaaaacg aaaattctat aggttcagtt actgttgcca taaaagaagt
     7321 caatgcccca gctgtcattg ctccttttac ttcttgtttc cttttatctt gtgctgtttt
     7381 atatatagca taagaaatag caggtattga gaacatcata attatgtaaa atcctgtcca
     7441 gaagaatcct gcatttgggt ctcctgccat aaatctagga atttctcctc ttataacttc
     7501 tcctgttggt gttgtatatt cacccatttc aaataatatg taagcattta aaacttgatg
     7561 taacccagtt ggtattagtg cacggttaca gaataaaaat aagaatattc ctattgcacc
     7621 agctcctccc aaccaaaaac caaattgatt cattgcagct tgtggatata tccataataa
     7681 actaaatata tatgataaaa ttaaagcaac tactggtgct agtgtaatta cacatttttc
     7741 tcctgcaaag aagcttaaaa atgctggaac tttaacttta tatgttttat tgtaagtcca
     7801 tgctatacag gctccaacaa ttatcccacc aaatacacct gcatttaatg tatcattcaa
     7861 taactctaaa tttgacttaa atatcatata tgcaactact gctgcaacca ttacacttgt
     7921 cttatcttta gactttgagt aggcactagc tgctcctaat aaaaataagt agtccacatt
     7981 tgaaaatact atagtagata tattagatat agctggtaca ttaagcatat ttggtccaaa
     8041 taataatcct aatatacctg ctgctggcat tacagctatt ggcactagca tagtttttcc
     8101 taaaagtgac agttgttgca tcattttgtt taagaatctc ttcatatcca atcccctttc
     8161 tatttcggtt taattttttg tgaaaacgat ttgtttacat tttatatttt aaatattata
     8221 tttgtttaaa caaattgtca atatttttta tttattttat cttcatcatt tagtttcaca
     8281 tctaaactct tttgagtata ttgctatatc tagcctattt ttttagttca ttttttttat
     8341 ttttaaaata tgtttaacca tttatttgaa gtaagctaca aaatagttca gttttatctt
     8401 ttttatagct tatataattc tattttcact atacatgtct aaacacattt gatataattt
     8461 gttcatatca attcaataat attactaaag acctttaagg aggggtaggg gtatatggct
     8521 aaaaataaat tttcagagat atatgaagta ttaaaagaag aaatacttga tggtaaatat
     8581 acaagtaata tgatgttgcc tactgagctt caacttattg aaaggttttc atgtagcaga
     8641 aacactgtac gtagggcaat ttctcaatta aacgcagaag gatatgttca aagtataaaa
     8701 ggcaagggtg ttgtagtgtt agaaaatagt tgttctaatg atttttttct aaatatgcat
     8761 aatttcaaag gtgtagaatc gattgtagaa gataaaaagg ttaatactgc tactagtgtt
     8821 ctccacttca gcaaaatctt aattgataat aagttatcta aaaagacagg ttttaagatt
     8881 ggtagtgaag tatattatct tcacagacta agatatattg ataatgtacc taaaatacta
     8941 gacattaact attttctatg cagtatagtt aaagaccttg atgtttctat agcacaaggc
     9001 tctatttata aatatataga agagtgtcta ggtacaaaaa ttgtttcatc cagaaagata
     9061 tttaaaattg aaaaagctac agagcttgag ttaaaaacgc tacctctaaa tgattataat
     9121 tgtgttggtg ttattaaaaa tagtgtatat actgatgatg gaaagctttt tgaatatact
     9181 gaatcaaagc atacacctga aacatttgta ttcatggatg ttactcaaag atattaaaaa
     9241 aattatgttt aattaaacat aattttttta cgtttagaca ctttatacta tactaatctc
     9301 actattctat aaataattat atgtttatac aaataatcat ttattttata ttttaccttt
     9361 agtttcagtt ttattcttga caatttgttt aaacatatta taattaactt ataaattaca
     9421 ggaggtatca agtatgaaaa attggtggaa aaaagcaacc gtctatcaaa tatatccaaa
     9481 aagtttcaaa gatagcaaca atgatggtat aggtgatata aatggtatta tagaaaaatt
     9541 agattatctt tcttcattag gtgttgattt attatggtta actcctatgt acgtttctcc
     9601 tcaaagagat aacggatatg atatagaaga ttattataat atagacccaa aatatgggac
     9661 aatgagtgac tttgaagagc tcttaaagga agctcataaa agagacttaa aaataatgat
     9721 ggatatggtt ctaaaccata catctactga acacaaatgg tttaaagaat ctaaaaaaag
     9781 taaagacaac ccatatcgtg attattattt ctggaaggat gctaaacctg atggttctgt
     9841 acctaataac tggatatcca ggtttagtgg aactgcttgg aaatatgata aaactactaa
     9901 ccaatattat ttacatttat ttgaggaaac tcaagctgat ttaaattggg aaaatgaaaa
     9961 agttcgtgaa gaatgttaca aaatactaga attttgggcc gataaaggta ttgatggttt
    10021 tcgtttggat gtggtcaacc tactatccaa aacacctgga ttacctgatg accctataac
    10081 agggccaaag ggagatggaa gaactcacta cgctgatggt cctcgtatac acgaatattt
    10141 acataatatg aatcaaaaag ttttcaaacc taaaaatata gttactgtag gtgaaatgtc
    10201 atccactaca cctgaggaat gtatcaacta tactagagaa aatcgagaag aactatctat
    10261 ggtttttagc tttcatcata tgaaaacaga ttataaagga ggcgtaaaat ggactaatga
    10321 aatgttctct ttggataaat taaaaaaagc acaatctgac tttcaatata aaatgtatga
    10381 aggaaaagga tggaatgctc tattttactc taatcatgac caacctagag ctttgtctcg
    10441 attcggagat gatagatttt ttcgtcaaga aagtgctaaa atgttagcca taacactatt
    10501 tggtttacaa ggtactacct atatatatca aggtgaagaa ataggtatga caaatgccta
    10561 ctttactaaa atagatgaat atgatgatgc cgagagtaaa aatgcatact atcatatgat
    10621 taaatctggc attgatgaaa aagaagcatt gattatactt caacagaaat ctagagacaa
    10681 tgctcgtact cctatgcaat gggataatac catttataag ggattttcta atcataaacc
    10741 gtggctaaaa gttaataatg acaacattag tgtagaaaat gagcttaatg attctcattc
    10801 agtattttat acttatcaaa gattaataaa atatcgtaaa caatatgata tttttacaga
    10861 aggtacttat agattgttag atgaaaatca taaaaatcta tttgtttatg aaagagagta
    10921 taaaaaccaa aatattcttg ttataagtaa cttcactcat gataatgtag tgtataaatt
    10981 acctgaaacc tatttgaata aattaaacta cacaatactt gaaaccaatt acactagaga
    11041 tacaattgaa aatgaaatgg aaataaaacc ttacgaaagt ataatgatat attgtaaata
    11101 aagttattta tgtaaaaatc ggtataacat cagagtgtta taccgattta ctaaattcaa
    11161 aataatattt atagaatctc tataaattac aataattatt tgacttctac attattatat
    11221 ttctttggat atactttagt catatagaaa tatataggaa ctacaattat catcccacct
    11281 aatccccaaa ctatcttcat aggctcatct atacctgctt ttatcagtaa taatatactt
    11341 ataataactg caaatattgg tataattgct cctccaggta ttctaaaatt tacatcttta
    11401 ccagcatact tctttctcaa tattagtaca gctaagcagg taggaatata ttgaataaat
    11461 ctagatacaa cacttatttg agataatgtt gtaaatgagc ccgaccatgc tattagtaga
    11521 gttcctatga cagatactat aattgctata tatggagctc catttttatt agtttttctt
    11581 atagacttag gcattaatcc ttgttcaacc aaagcagcag cagaccttgg tgtaaatatg
    11641 gatgatgcaa tatttatacc tccaacagat actatggttc ctattgtaat tatataccca
    11701 cctatagggc ctaacatctt aatggcagca tctgcaacag gagtagttga acctactaag
    11761 ccattaccta atactcctat acttattcct agtataagca tatatattac tgatactaca
    11821 aacattacca ttaccagtgc tttaggtaca tttttcttag ggttctccat atcttttgct
    11881 gcaacagcta aagattcaaa ccctgtaaaa gcataaaata aagttataga tactgctaca
    11941 aaagctgatg atgaactttg acctttttgt attattacaa atggtgtaaa attagaaccc
    12001 tttataaaga ataatcctac agctataaat aaaactattg gtaataattt tcctatagtc
    12061 attatattat ttaattgctt agattgtttc atccccataa agtttataat cccaagccct
    12121 acaactaata taccaattat tatattttta gtaagtggtt ctgctgcttg tggccataca
    12181 gatgatagtg ttacagcaaa gaaatttgcc atagtcgccc aagcaatcat actaactatc
    12241 cacttcataa atccaacttc aaatccaata aaatttccaa atgcctcttt tgcataaaga
    12301 tatggacccc catcagtatc aaaccaacta cctgcttcag caaaacataa agcaatagaa
    12361 acagctaaaa gcatacaaaa aactaatact aatatacttg ctggacctat atctgtataa
    12421 gcatcaccag gtaatccaaa tatacctgac cctactattg cattgattcc taatagtaca
    12481 atactccaaa aacctaactt aatgcctttt tccattgtta ttccccccaa agccaactta
    12541 atatagttat aattattttt cttttgatgc ttctttaact attgccataa atattttttt
    12601 catattatca taatctttag tcatcatttc tggatgccat tgtattccta ttacaaactc
    12661 acttccttcc ttttctatag cttcaattaa accgtcttta gatgtagctg aaacaatata
    12721 tcctggtgct actttgttta caactaaatg atgaaaacta ttaactaaaa tttctttttc
    12781 tcctaatatt tcatataatt ttgtatcctc ttttatcagc gctgtatgtg taggtatgtt
    12841 agataaatgt tgttgattgt gtttaatata agcgccttca attagagata aatcttgata
    12901 caaactacct ccctcagcta catttataat ttgttctcct ctacatatac ctaaaactgg
    12961 ttttttcata tctaaagcat attttaataa tttcatatca aaaacatctc tttttggtga
    13021 tattgcacct aacttattat gaggttcttc tttccatatg agtggattta tatcttgtcc
    13081 cccagatagt ataagcgcat ctatattaga tacttgttcc tttataatct catcatcata
    13141 tacaattggt acaatatatg gtatagcttc gcacataact actgattgta tatagtcatt
    13201 atttacataa gctctttcat agccaggaaa cattcctcct tcatcaatta ataaattacc
    13261 cgatattcct attattggat atttcttttt aaccaatttc ttcacccctt cacttattcg
    13321 taaacaataa aaaatgctac ttctcttaaa gagcaagtag cataccaata ttttatttat
    13381 ttgaatatta taatttattt tagaaatact ttttttaaat actagtaata taaataactt
    13441 tctttactta tattttattt taatcctgtt tagtttgact tttttaaatt gttttaagta
    13501 caattaatag gtaaaatagg tatttatatt ttccttttta ttaacctatt acatgctgtt
    13561 taatatattt ttaccccttc tatttaattc acttcccctt ctaccagatt cacatattat
    13621 caagtccagc tcttttagta tattaagtat tcctcttacc tcaccttctg ttatactata
    13681 gcctaattca tttattgaat taacaatacc atttctacct atatttttat taagattatt
    13741 ggcatttttt agacacccca tcactaactt tactttttct aaagatgttc tatcctttaa
    13801 tatacttatt tctttactaa aatcttcagt tatatttaat aagttatgag gtaaatcact
    13861 tattaaaata acatcttcag agctcataat gttaatatac atagcagtat tttttaattc
    13921 tcttatatta cctggccatt catatgcatt aataatgtct tgaacatctt gactaattgc
    13981 tctcttcctt ttcataaaat gcttcaacat aacttctata tcttcttttc gctctcttaa
    14041 aggcggtata tttacaggca atacatttat cctatagtat aaatctgctc taaatctgtc
    14101 ttcttttatc atttctaata aatttttatt tgtagctgca attactctaa catctatatc
    14161 tattacattc tctcctccaa ctctcattac ctgattctct tgtaatactc taagtaattt
    14221 gctttgtaag tatataggca tgtctcctat ttcgtccaaa aatatagttc cattgttagc
    14281 ttgttcaaat aatccttttt tacctccttt taaagctcct gtaaaagcac cttcttcata
    14341 tccaaaaagt tcgctttcaa gtagattttc tggcatagct gcacagttta ttgctataaa
    14401 tggttgacta tgtcttggtg atgcattatg aatagactga gccataagtt cttttcctgt
    14461 tccactttct ccagttataa gaaccgtata atcagattta gctattttca tacctaattc
    14521 cttagttctt tccatcttta gcgaaactgt ttttatatcg tcgaaagtat atctagcaac
    14581 ttgtcccttt tctctaagct tctttgatag gttttgctcc aattttctta tgtaagttat
    14641 ttcttgaata caaaaataat atccagtaac ccttccaaaa ctctctatat tatacttatt
    14701 tacgtttaag tacttattat taaattttat aacttcatca tgtgccttac tcaacctaaa
    14761 aatcttttta atattctcat tctctaattc atctatattt ttccctataa tattaccttg
    14821 aatatctagt atattactta gactattatt acaaataatt acgtttccct tatctgatat
    14881 cattgcaata cctaagtttg ataaatttat tatggaattt aattcatctg cttttatagt
    14941 aagttctttg tatttagtat ttattcctga gtataaacta attatttcat ctgtatactt
    15001 aattagcctc tcagtaattt ccttatcatc cagtttgagt tttgctatta tttgaataaa
    15061 tgttgaacta tcaatatatc tatgccctaa atcaataact tcttctatgt attttggaac
    15121 taaacttgcc tctcctggtg ttatagctat cttaatattt ctatattctt cattgggatt
    15181 atatggtata aaattcaagt gatttattcc tatattatat aaattagata ttgtttccaa
    15241 tacagtatgt ttattatcgt ttactactaa tacatctatt ccttctggca atgagaataa
    15301 cttatatata tccttttgtt ttatactcct atttatagtt attatctttg agacatcttc
    15361 tacatatttt tttattttta atactctatc atctatcatt accaatatta tgtcatcttt
    15421 tatcagctcc ttttctgtta ttttatttaa ataataattt tttatcatta ctttatcttt
    15481 aaatatcatt tctagatttt tatttaaaaa acattctaat ttagacaatc catcagttac
    15541 tactgctatt gttttcattt tattactcct tttaaaatat actctactct tttataatat
    15601 acatttgatt tccactttaa tagcataaaa aattgtacat ttagtatact aacatattca
    15661 tttattagtt ttatttccct aaacatcata gttgcaatat atatcatatt tcttaagctt
    15721 atacagcaaa aaatgtgcca aattaataat tttcttactt ttattttaaa gttcttcaat
    15781 cgtatttaca gacttagcat ttataaatta taagtcttta tattattaat ctatttttat
    15841 aggttaatta tacaaatcat ataccacttt tacccattaa attcattata aaaaagatgg
    15901 aataacgaat tgttactcca ccttttttgt aataaaaaat tgtatatata aacaccattt
    15961 gacactcttc taagtacaaa cagtatctac atgctataac ctttcaccat tagattctat
    16021 tacttgttta taccagttaa aactcttttt cttaatccta gacaagtctc cacttccatc
    16081 atcatacttg tccacatata taaacccata tctcttggcc atctcaccag tagatgcgct
    16141 tactaaatct atacatcccc atggagtata tccaaacaaa tcaacaccat cttctacagc
    16201 ttccttcatt tgctctatat gtgctttcaa atactctata cgatagtcat catttatcac
    16261 tccatcaggt tcttttttat cataagctcc taaaccattt tcaaccacca tcataggtat
    16321 tctatatcta tcataaattt catttagtgc atatctaagc cctttagggt ctatttgcca
    16381 tccccattca ctagactcaa gatatgggtt ttttactcca cctaatatat tgccacttgt
    16441 attactttct ttagactcac tacttacaca tgtagacata tagtaactaa atgtataaaa
    16501 atctacacaa ccttctttta aaatttctaa atctcctttt tccattttta tctcaatatt
    16561 attttctcta aaatatctat tcatataagt tggatattca ccacgcactt gtacatctcc
    16621 acagaagtaa ttcattactc tattatcttc ttgagtctta actacatcat ttggattaca
    16681 agtataaggg tacattgttg caaatatctg catacatcca acttgataat ttgaatctat
    16741 ttcatgagct aacttcacag ccttagcact tgctacaaat tgatgatgta acccttgaaa
    16801 acgaagttga ggtatatcta cttggcttat aaaatctgta gttccttcat ttaatatccc
    16861 ttgtgacaag taccctccca taggcattgt agctgaattt atttcattaa atgttaacca
    16921 atactttact ttccctttgt atcttttaaa tattgcctca cagtaattca tatacaagtc
    16981 tattacttct ctcgaagccc atccattgta tttctctgtt attgcaaatg ggacttcata
    17041 gtgagatatt gttattaatg gttctatatt atattttaag cattcatcta ttacattttc
    17101 ataaaattta agccctgctt catttggttc tttctccatt ccagttggaa atattctagt
    17161 ccatgctatt gaaaatctaa ataccttaaa tcccatttct gcaaataaag ctatatcttc
    17221 tttatatcta tgataaaaat ctattgcttc atgacttggg tagaacgttc ctttttctat
    17281 agttcttgtt attcttttac ttactgtttg agaacctcca gtacacatat ctgaacaaga
    17341 tgtacctttc ccatctaaat tccatgctcc ttcacattga tttgctgctg ttgctccacc
    17401 ccataaaaaa tcttttttaa atgacatatc tatatcctcc tattataatt ctttaccatt
    17461 tgattctatt acttttttat accagtcaaa actcttcttt ttactacgtt ttaaagttcc
    17521 gtttccatca ttatctttat ccacatatat aaatccatag cgcttcttca tttctccagt
    17581 actggcactt actaagtcta tacatcccca tggtgtgtat ccccacaaat caacaccatc
    17641 taactcaaca gcatctatca tagcttttat atgagcacgt aagtaatcaa ttctatagtc
    17701 atcatttata ttcccagttt catctggatt atctactgcg cctaatccat tttcaactat
    17761 aaataatggt ttttgataac ggtcatacaa agaattaata gttattctaa gccctagtgg
    17821 gtctatttgc catccccact cacttgcatc taaatatgga tttttaagac tttcaaaaac
    17881 atttccttct gttaaaatat ttacttcagg gtctgcactt gtaagccttg atgaataata
    17941 tgagaatgat ataaaatcta ctgtgttctc tttaagtatc tttttatcat cttcttccat
    18001 cacgatattt attccttttc gttccaattc ttttaatgca taagctggat attctccacg
    18061 agattgtaca tctataaaaa agtagttttc cctatctttt tctatagatt tccatacatc
    18121 tagtggatta caagtattgg cataagtatt ccccgctgct atcatacacc ctattttaaa
    18181 ttcttgattt atgttatgag ctagtttagt aactaatgca cttgcaacta attgatgatg
    18241 tgcagcttga tattttattt gttcttcatt ttctccctct tcaatataga gacctgcacc
    18301 tataaatggt aaatgaagta tcatatttat ttcattaaat gttagccaat actttatctt
    18361 atctttaaat cttgtaaaaa taacttcaca atattttaca tataaatcta ctagcttacg
    18421 attcctccat gctccatatt tttttactaa atacattgga acatcaaagt ggcagattgt
    18481 tactactggt tctattccat actttaaaca ctcatcaaac aaatcttcat agaattttag
    18541 accctcttca tttggaactt cctcaattcc tgttggaaat atcctagtcc atgctattga
    18601 catacgatag catttaaacc ccatctcagc aaataatttt atatcctctt tgtaattgtg
    18661 atacatatct attgcttcat gagctggata ataatgctcc tcatcacatt caaacatttt
    18721 cattttccca gtcaaaactg gaaatctatc ttttccctgt ggtataacat caacattagc
    18781 tagacctcta ccaccttctt tatacccacc ttcacattga tttgctgctg ttgctccacc
    18841 ccacaaaaaa tcttttctaa gtgccataac tctacctcca ataatttatt tatagtaaat
    18901 ttattttaaa ataaaaatac atatatctaa ttctcaatta ataaagccgt cctttacgct
    18961 aaaacagtta tcaattcctg actattactt atatgctttt gtgtattttc tacgatatcc
    19021 acataatcag aataatttgt aacgactact ggagtttcta agcaatatcc ttcttttgat
    19081 atgctttcta tatcaaaagt tagtaatgtc tgaccttttt taatcttatc tccttgattg
    19141 acaaaagatt tgaaatactt accttctaac tgaatagtat ttaaccctat atgtatcaat
    19201 aattcacaac cattatcaga tataattcct attgcatgtt ttgttggaaa taaagtcatt
    19261 acagtcccat caaatggtgc tactactttt ccttcttttg gtgttattgc tacacctttt
    19321 cccaatacac ctgttgaaaa tgctgcatct tgcatatgtt ccaaagcctt tacttcacct
    19381 tttattggac tatatattac ttctcttttg tttttttcta cagcgccttt actattatta
    19441 tctttggaaa tttctactat agtatcatct ttccaaagaa agaatgttaa tacaaatccc
    19501 accacaatgg ctactattat agatattgtc gttgcataaa cacctgtcat atctccagtt
    19561 gttggattta tataattagg tataccaaat attccaagtc cacccattac ataacttttt
    19621 acattcatta ctcccattac agctcctgct acagcaccac ctacacaact gtatatgaat
    19681 ggttttttcc ttggtaaagt tattccatat attgcaggtt ctgttacacc acatattcct
    19741 gaaataattg caggtataca caactccttc attttcttat cttttaattt aaagtacatt
    19801 gctgccacta ctgctgtttg tgcaaaagat ggtacaaatg ctcccactaa tattgtgtca
    19861 aatcccatag tcataaggtt tgacatagct attggtacta gtccccaatg tagcccaaat
    19921 attacaagca cttgccacaa taaaccagtt aatgcgccac atagaattgg tgaaaagtta
    19981 aataaagcta aaaatccatt tccaactata ttagaagcat aggtagctat aggccctata
    20041 accataaatc ctaatggtaa agaaactagt aaaactgcca ttggtacaaa gaaatttttt
    20101 actacatctg gtattatttt agcaaacatt ttttctaact tagatgctaa gaatactatt
    20161 aaaattactg gaactactgt tgaagtatag ttcattgcta ttactggtaa tcctaagaaa
    20221 gttatatata ctggtgattc aaatattgtt cctgtaaata gattgtataa aggttgacct
    20281 gttgatgcca gagtgtccaa ttgaatacct gaatagcaca aaactgcacc tataagcata
    20341 ccgataaatg gttttagctt aaatttctta gcagctgtat atccaagaat tataggcata
    20401 tactggaaca ttgcatcacc aattgcattt aacataatat acgcaccatc agtttctcca
    20461 tacaaaccca gtgctgtaaa tactgcattg aaacctttta tcataccagc agcacacagt
    20521 actcctagta ttggttggaa aactcctgat attatgtcta taaacttatt aagtaatcct
    20581 tttggtgaat ctgaacctga attatctatt gtatctcctc ctaatccagc caaatcacac
    20641 acaacttcat aaacatctgg aacatggtta ccaataacta cttgatattg acctgtactt
    20701 ttcattacag taactattcc atccattttt tttagtacat catcatttgc tattgactca
    20761 tcttttaact taaaacgtag tctcgttata cagtgagata aactgctaat attatccttt
    20821 cctcctacat tctcaatgat ttcttttgat agttgttcat actttctcat tttttatcct
    20881 ccattttctt tttgaaatat gaaggtttgg ccaacttaat gtcaccaccc aatatatata
    20941 aacctaatta ttaggattta tatctgattt aatacttttg cttaccaccc tttcgacatg
    21001 aatagttaag tataattttt cctcatctgt taaattgtaa ttgtattttt tatgtataaa
    21061 ttcatctaac ttttctatgc atttataagc atttttatat ttgactttta ttacctttaa
    21121 taaatcatct tcattatttt catgtaaatt attactgaca actctttctg caaagtactt
    21181 taagtgagtg ataaatctat gataataaac tgaatcttca tcaaatacta ttctataatg
    21241 gtacttaacc acatttgcga tttcttgtat tatttgcgta atatcatata taatttttat
    21301 actttgatcc atttgtgcat taactatatg tagtgcaata aatcctgctt catcttctgg
    21361 caatctaatt tcaaattttt tttctatata atctaaagcc tttaaaccta tgttaaattc
    21421 atttttataa aatcttttta tatcccaaag taatacattt tttacattta ctccttcacg
    21481 agctctttct attgcagtat acatatggtc tgttaaagaa atataaatac tatcatttaa
    21541 tcttttccct agtttttctt tagcatataa aattatttca tctgataatt ccatatattt
    21601 cataggaata tctgctatta attctttaaa tttatcacat atatttggat ctgaaagttt
    21661 gaatatctta tcaatcttat cctttgatat atggtctcct gtacgttttt tataagctaa
    21721 acctcttccc ataactacta tttccttatg attttcatca gttgtaataa ttacattatt
    21781 attgagtatt ttttcaataa tcattttgat gcctccttta ttagcattaa gttaaaataa
    21841 atctttttta attatttaga atatttaaaa tgtaatttat tacataaaaa aaaacctatt
    21901 tattacacat tgaatagact cccatgagcc ctgagtaata aataggttta gcttgtattt
    21961 aaacaatcac tatccgtttg tattttattt taattattat ttattatatg ttagcaaatt
    22021 tattttttag tgtcaacttt ttcttaatat tttaattttt aataaactat ataaattgaa
    22081 tccacaaaaa tattattttt atcaataatc aatataaaaa aaggtattac tttttttaag
    22141 taataccaat ttatttttaa tttaagtgat tttttttaat ctcatcaagt agtccatctt
    22201 ctaaataaat ttctaatgca catcctacca ttgcctttac tgctttgtga agtttgtcat
    22261 aagcttcctc agaatttgca tagcttagaa actctttttc atgaacatat accattggat
    22321 ttatatctaa agctatttct gtatacatag taggacaaac ttgacttaca ttccctatgt
    22381 ctgtagaacc tactggacca tctttacctt ctaatatatc tgttatacct gcctcaatca
    22441 aattattttt tgttatcttt tgaagaactt tattatttat tatgttgtca aaagaatttt
    22501 caaaatatct ataagaaagc ttcgctcctg tcattaactc tgcacctttt gcacagttta
    22561 taaccttttt agttacttca tctaaataac ttctttcagc agctcttaca aaaaacttac
    22621 aggctgcttt ttctggaact atatttggag cttctcctcc atttgaaact attccatgta
    22681 ttctaacatc tgattttaca tgttgtctta gtgcatttat cccagcaaaa gtaagttgta
    22741 ctgcatctag tgcgttgact cccatatgag gatgactagc cgcatgtgct gatacccctt
    22801 caaaactaaa ctctaatgaa tctattgcca aagccttgca atttatatta ttaaaagctt
    22861 ctatatgcat ttgataactt acatcaacat catcaaaagc tcctgcctta actaaatcac
    22921 attttcctcc tgttgtttct tcagctggtg ttcctattag tacaattttt cctttaaaat
    22981 tttcttttaa cttacttaat actatacaag ctcctagtgt agatgctgca atccagttgt
    23041 gcccacaagc atgagctggt tctttatttt ctccatatcc aggaagtgca tcatactcag
    23101 ctaaaaatgc tatagtaggt ccatcattat ttcctaattc agctctaaaa gcagtctcca
    23161 tattgcaata cggataaatt gtatcaaatc catattcctc cattttctct actaagtatt
    23221 ttgatgatat atattcttct tcccctaatt ctggattgtt aaatataaaa ttacaaactt
    23281 cttcaatttc ttttccaagt tcattctcta tctcataagc tcttttcttt atactctcta
    23341 tcataactta cctcctacta gaatcctaga tataatccta ttgtcaaaaa taccattaca
    23401 agaactgtca atgctaccat taaaggaatt atgaatctaa cccactttga ccaaggaata
    23461 ttggctactg ctagtgctcc cattaaaaca cctgatgtag gtgttattaa gttagttaca
    23521 cctataccaa attgataagc tgtaactatc atttgtctag atacatctac taagtcccca
    23581 agtggtgcaa gtacaggtat tgtaagtgat gcaagtcctg atgctgatgg tattaaaaat
    23641 gctattaatc cttctattaa gaaagttaaa tttataaata tagtttttgg taatccgttt
    23701 aataaatttg ctgcagaatt taaaattgta tctattataa atccattttc tgctattatt
    23761 acgattccac gtgcaaatgc tatacacaat cctgctgtca ttaaatctcc agctccactt
    23821 ataaatgaat taactatatc atcttgttta agacctgatg ctatacctga tattatacct
    23881 atagctgtaa atatcattgc aatttcagtt atataccatc ccaactttaa aactccatat
    23941 atcataatcg ccatacctat tgtgaaaatt gctattacca tggcttctct ttttgtaaat
    24001 tcttttatgt ttgaatcact attaaccatt gactcttgat ttagagatat atcgtgtact
    24061 aaagattttt tagggtcttt tttaacttta ttggcataca tcataacaaa ccctatagat
    24121 atagccatat atattataaa cataacaact ctaaactcta ttccagaacc tggagttatt
    24181 tgtgataatg cttgtgctat tcccacagag aaaggattag tagtagctgc tccaaatcca
    24241 gctgttgctc ctataaatac tgtggccact gctgtcaatg aatcatatcc catactggtc
    24301 ataagtggaa taaatatcat ataaaaaggt agtgtttctt cactcattcc aaatgttgtt
    24361 ccacctagtc caaatagaat cattgaaata ggtattatta aaaattgaaa cctcttcatt
    24421 ttatttacgg tatgagctat aacagcttct atagcccctg ttttattaac tatcccaaaa
    24481 gctcctccaa ctattaaaac aaatccaact acttcagctg catctataaa tccgtttata
    24541 ggtgctgtaa atacatcagt aattccttgt ggatttgatg gtgctttttc ataagttcca
    24601 gctacaacaa ctgaccttcc atctatatct actctttcaa aatttccact tggtactatc
    24661 caagtaagaa ttgccattaa cactattagc aaaaatatta ttgtaagtgt ctgtggcata
    24721 gtaaactttt tcttttttaa actgctcatt tttaatctcc ccacttttta aattaaaata
    24781 ttttattatt gcatcccttt atcctatttt gtatagatgt aaaaaagctc aacatggata
    24841 catgttgagc taaatgtgct aaatacaaca tacctgcatc ttccctttat cttgtttaag
    24901 atagctctcc atcaaaattc gggataattt tgatgacagt actgtaccta ttaaatacag
    24961 tcccagcact agcttcggac actagtactt cggcacttac tccttttata ttgcctcatt
    25021 ggtttccgac ctcttcaata ttaatcttag taaatgcaac ctctacctca atctttttat
    25081 tagatgaggt aattcttatt aatttttatt aattcaaagt aattgtagca taatatgtcg
    25141 agattgtaaa tattttcagt ataataattc ttactttatg atatgattca atttttcaca
    25201 aataattttt tctccatata atttaaataa tgtagcatat tttgaataca cacaaatttt
    25261 ccatgaattt caaattattt taataccctt ataataaaaa attaaagcca tgtaaactta
    25321 tcaatttaca cggctttata tacattaatc tacaccaagt accgctttga gttttgatgc
    25381 tattgtaata actcgtggtc caaatataac ttgaactgag tttttctttt taacaactcc
    25441 acttgcaccc aattcattta cccagaaacc atcatcatag aatccatcaa ttgaatttaa
    25501 ctctacccta agtctagttg cacagtttgt aacatttttt atattactac ttcctcctaa
    25561 accttctatt atagagtgta caagctctgt atctttatca tctacttcat ctcctacagc
    25621 attgttatat actgttttac cagcatctac agattgtttt tctctatatt ctttcttgct
    25681 ataaagctta acttcttctg aacttcttcc tggtgtcttt atatcaaact tcttaattgc
    25741 ccatgtaaat attatataag taactataaa aaatattggt atcaaaaata ataatggtaa
    25801 tgcatccact ttttggggtt gcaatagatt aggaaacata tttctaaatg attcccccat
    25861 tatagaaaca ttaaacattt ctgtaaatac atacgtcaat cctgctagtg gtacatatgc
    25921 taaaaagtac aataatggtg caacaaataa gaatgtatac tctattggtt ccgttactcc
    25981 taccaacatg gctgttacta ttgctggtat taatatactt attgcttttt tcttattgac
    26041 attatcagcc aacttataca tagctaaagc tgctgctggt aatattgcaa aatgtattaa
    26101 taaacgtcct gttgtgaagt tacgagttat ataagatagt gtatctgggt ctcccatttg
    26161 agctaatctt atattgttaa caccctcgta aattgctcca cctacttcca ttgttccacc
    26221 aactcttgta tattctatag gaaatgcaat taagtgatgt ataccaaatg gtaataatgc
    26281 tttatccatt gctccaaaag taaatgttcc taataatcca ctagaaccta tccaattacc
    26341 aagtttagat aatgccaacc ctactggtgg ccatataaag tacattgctg tacccaatac
    26401 tattgatgct ataaacatca taatcattga aaatcttggt cctgagaaaa aagataatgc
    26461 actaggaagt tctatgtcaa caaatttgtt atgtactgca ctagctacaa atccagctat
    26521 tatagctcca aatatactac aatcatatga aaatattccc aagaaagaac catataagga
    26581 acttcgacta tatgcttctg cctcgcctaa tccagatgcc ataaacgctt ctgctgtaac
    26641 tgtatctgaa tttataccat ttgctgctag caatgtactt ataactgtgt gcattcctat
    26701 aaataaaaca attcctccta atgcacccca tcctttttcc tttttagata atccaaaagc
    26761 tatacctgta acaaagaata ttggtaaata tctcattacc ataaacccta ggtcgtttat
    26821 tactttaaag aatacattta taaatgaccc ttcttttatt attccgctaa gccctaatgc
    26881 ataaacgttt tccatatttg caaaagctga ccctaaccct ataaatactc ctgctacaac
    26941 aagtaatata acaggaatca tcattgctcc agaaagtact tgtaatttat ccttcatagt
    27001 attatttcct ccatttttat tgaaatgcca ggctatataa tgcatatata tatacttcta
    27061 ttgctttgta taatgtatct atacttatat tttcatttgc ctgatgtgaa tttggattat
    27121 ctccctctat tgtgggtcca aatgcaactc cattttctaa tactcttgca taagatgcag
    27181 ctccttttgt aaaaagttct gcctcttttt caaaaccttg tttatatgca cttgataatt
    27241 tatttattaa ttcactatct ggttctacat acagtaattt taaattctta tatatatcaa
    27301 ttattaaatt ttcttttttt ccaatttcat taattctatt agttataaac tccaaactta
    27361 tacccttagg atatctaaaa tctattttca tattcaattc atttttatct aagaagatac
    27421 tcattataca tattgtagaa acgcccatat ctacatcttc tttatatatc cctatttttt
    27481 ttccatgatt atcatctgta aagtatgaat ttaaaatatc ctttattata actcctttat
    27541 cgtttagccc tttaattctc tctaaatctt ttgctaaact aaatgcacag ttatatgacc
    27601 tgtgtggatt tctcgacaaa gctctttctc ctgtatatct tactaatact tttccttctt
    27661 ctacttcttc tatttctgta taataagcta atgattctac taaatctttc ttattattag
    27721 ttttaaagac agcctcaatt ttgtcacata caaatccatc ttctttgttt gactttatat
    27781 caactaaatt gtgatttcta aatttatctt tatctatttt ctttcttaga ttgaagtata
    27841 aaataccttt ttctccattt actattggga agtttccatc tggagaaaat gcaaattttg
    27901 gctgttcatt tacactaaaa taatgttcca tacattccca agtcgtctcc tcagctcctc
    27961 ctactatcaa tctaatcttt ctctttggct tttcattaag ttctcttaag aaaagtaatg
    28021 catataaaat ccctatcaaa ggtcctttgt tatcattaac tcctctacca taaagatagt
    28081 tatctttttg acatacttta aaaggtttac tcttccaaag ttctttatta tatattggca
    28141 ccacatctat atgattaagc acccctacta cttcttctcc ttctccatat tctatatgaa
    28201 ttgcatatcc atcaaaatct tttacaacaa aatctttgtc ttttgctatt ttaataagct
    28261 tatcgaaggc atttcttatt tctatcccaa atggttgatt tatatctgtt gtactttcat
    28321 ctctaattga aggtatttca actaaactcc taatatcctt tatgatattt tcttgattgg
    28381 attttaaata atcaataatt agttctttat ttactatcat cttaattatt tatcacccct
    28441 ttatattagt tttacaaagc atttcagttc atatttacat tataaatttt gagtattatt
    28501 ttttcaatat ttcaaatact tctctaaatt accataatga tacggtaaat aatcaacaga
    28561 ttatgacaaa attatactat acctactatt aatattttat cttatctatt acatcttttt
    28621 taatgtaatt ttattccatt aaatgatatt aaaagtaaaa cattagagat attttaaata
    28681 tataaaaaat ggatgtaggt aaatttattt ttatgtaaat ctacctacat cccatgattt
    28741 tattaaacaa ttatattata atattcatat ctatgtgttc tataccttta atagttatag
    28801 ctttatctaa tactttacta atcaactaat taaattcaaa agattttctt ttaaataaca
    28861 ttctaaatta agttacataa atcttgaata aattgcctct gttattaaaa catctgaccc
    28921 cataatataa aataaataca tacactttac aacatttta
//
LOCUS       DBGJFK010000045        28512 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.045, whole genome shotgun sequence.
ACCESSION   DBGJFK010000045 DBGJFK010000000
VERSION     DBGJFK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28512
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.045"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            226..1146
                     /locus_tag="ACOIAP_002316"
     CDS             226..1146
                     /locus_tag="ACOIAP_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HGZ2639198.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLIIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPTRYEDVAYEVKEEEK
                     TDEDNEVDTIINKGMNYLTHIKEANKNIKSESMCDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            1261..2418
                     /locus_tag="ACOIAP_002317"
     CDS             1261..2418
                     /locus_tag="ACOIAP_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HGZ2639199.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTSDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(2506..4005)
                     /locus_tag="ACOIAP_002318"
     CDS             complement(2506..4005)
                     /locus_tag="ACOIAP_002318"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGZ2639200.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            4600..6024
                     /locus_tag="ACOIAP_002319"
     CDS             4600..6024
                     /locus_tag="ACOIAP_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HGZ2639201.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWIIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TIAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDNTSLEEAKAKVSDMKSVSKNSKKDIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDVLFKRLESK"
     gene            6049..8187
                     /locus_tag="ACOIAP_002320"
     CDS             6049..8187
                     /locus_tag="ACOIAP_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2639202.1"
                     /translation="MDNLKKKKITSRQKKIILMIVENSKKNIPITISEIAGMLELSSR
                     TVLRDMSGIEKWFDENDFNFVKKPGVGLILEESIENQNFIIELLEEEKIEKEYSKEER
                     NLIILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVY
                     LKGQEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKTIEILSENRLLNLMDKCI
                     IRKVEGTLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITE
                     EFKLAKEIVKGMEIDFSMDIPLDEVGYITMHIRGAKQRSSSNHNALNLDDIEVMDITN
                     KMIDLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYVYN
                     GVEKISRIIKDKLSINSIPESEIGYIAMHFASAIEKNLMMYANINIVVACPTGIGTSR
                     FLSTKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSL
                     DDEQLIKEKIKSIAQNKLINLNVKNGTKNKNKIYAQITESMNIGKDILQFLEEIRFEK
                     FESKDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCISERID
                     IMKLSIIKLENRIILDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKI
                     NKFSIEEMILEVKDIVFNFYTNRLKAFIDK"
     gene            8217..8639
                     /locus_tag="ACOIAP_002321"
     CDS             8217..8639
                     /locus_tag="ACOIAP_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2639203.1"
                     /translation="MNKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            8658..9809
                     /locus_tag="ACOIAP_002322"
     CDS             8658..9809
                     /locus_tag="ACOIAP_002322"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGZ2639204.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVEAEIITTAVGPLVLTKIASTIAK
                     GIKNRKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYIGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFIYDIVKSAMVESGEGLIKKYNFDSEAHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYDLSVDNLILGIGAALHYN
                     NSEDAQSVELQELIKSNGVKKAVAKIANINNDEELLNNIEKSYIFMENL"
     regulatory      9915..10016
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            10199..10771
                     /locus_tag="ACOIAP_002323"
     CDS             10199..10771
                     /locus_tag="ACOIAP_002323"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGZ2639205.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFEGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANNVRLESLAVVESIDNGTVKFR"
     gene            10835..11485
                     /gene="fsa"
                     /locus_tag="ACOIAP_002324"
     CDS             10835..11485
                     /gene="fsa"
                     /locus_tag="ACOIAP_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGZ2639206.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            11637..14561
                     /locus_tag="ACOIAP_002325"
     CDS             11637..14561
                     /locus_tag="ACOIAP_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2639207.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKS
                     GIKDKDLASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCENEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSQIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTIG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKDHIEKQIKEYDASIEVKPIAFLNNNLEDELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            15150..15608
                     /locus_tag="ACOIAP_002326"
     CDS             15150..15608
                     /locus_tag="ACOIAP_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2639208.1"
                     /translation="MEFINFVSDKVIELKMDCKTKENFFKEIHNKVFDLGFVKEEFGE
                     KILERENVFPTGLNLGDYGVAIPHTDAEYIKEQFIAVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            15661..15936
                     /locus_tag="ACOIAP_002327"
     CDS             15661..15936
                     /locus_tag="ACOIAP_002327"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639209.1"
                     /translation="MKKILVACGAGIATSTVVCDKVEKLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            15995..17269
                     /locus_tag="ACOIAP_002328"
     CDS             15995..17269
                     /locus_tag="ACOIAP_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGZ2639210.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKLVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLLLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            17400..18452
                     /locus_tag="ACOIAP_002329"
     CDS             17400..18452
                     /locus_tag="ACOIAP_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGZ2639211.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYANIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDVNPVEK
                     IKELTDGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            18452..19483
                     /locus_tag="ACOIAP_002330"
     CDS             18452..19483
                     /locus_tag="ACOIAP_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGZ2639212.1"
                     /translation="MKAVVKTKPGYDNVEVLDVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCQTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            19574..20386
                     /locus_tag="ACOIAP_002331"
     CDS             19574..20386
                     /locus_tag="ACOIAP_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGZ2639213.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVMVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            20389..21309
                     /locus_tag="ACOIAP_002332"
     CDS             20389..21309
                     /locus_tag="ACOIAP_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGZ2639214.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGVNVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            21484..21930
                     /gene="rpiB"
                     /locus_tag="ACOIAP_002333"
     CDS             21484..21930
                     /gene="rpiB"
                     /locus_tag="ACOIAP_002333"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HGZ2639215.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEIEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            21960..22625
                     /locus_tag="ACOIAP_002334"
     CDS             21960..22625
                     /locus_tag="ACOIAP_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGZ2639216.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVRADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYIGLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIKELKE
                     SIK"
     gene            22735..24237
                     /locus_tag="ACOIAP_002335"
     CDS             22735..24237
                     /locus_tag="ACOIAP_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HGZ2639217.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVRKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSAVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGSIMITASHLPYYYNGLKFFTESGGLEKADIKEMLDIADKNDSVDYEKANKKGKV
                     ISKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRYKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAREEKEVRIGINKEDFRPYAEDILKDLDSHVRSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLRGL"
     gene            complement(24549..26141)
                     /locus_tag="ACOIAP_002336"
     CDS             complement(24549..26141)
                     /locus_tag="ACOIAP_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HGZ2639218.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLISILFEAVYDLNNNFFYN
                     INYYYKEFTIPYFYFFGTPLHLSKVELEFVCIGVILSSFLLIVLCFILYKKNKQTKVK
                     FLENVISLFSKVKIELTLILILILLILRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLSVYNRKTINKKLAIVFLISIVMQAIIQNMVLIFF
                     MYIYYAEAIAIVILFTLVNTVFHLYIYNFLSAKFNYINNISKNVKNIENGDLKYKLEV
                     IGNDEISDLSKSINNITDGLENAVDSSIKNERMKTELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDKETVNDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSNLDFIIETPEHAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELVERFRRGDVSRKTDGSGLGLSIAQNIIELEN
                     ADMEIIIDADLFKVMLTFRRVN"
     gene            complement(26110..26826)
                     /locus_tag="ACOIAP_002337"
     CDS             complement(26110..26826)
                     /locus_tag="ACOIAP_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639219.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLKPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKVIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSREIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(27369..28169)
                     /locus_tag="ACOIAP_002338"
     CDS             complement(27369..28169)
                     /locus_tag="ACOIAP_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGZ2639220.1"
                     /translation="MTFKNKKFTISKYRILSIILALCLILTAFSSYMNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTDIQK
                     SEYRNREFLASLNSLGVRRENIILLPETNTNGNTDFNYMEKIAINFEENFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEDREGIGYKSDHKSFDKLLRNKDVPAILHTPNL"
BASE COUNT        11425 a         3184 c         4874 g         9029 t
ORIGIN      
        1 aataaaaacg agggaactta aatttaatta aagttaagtt ctcttatttt tatatggagt
       61 taaatgtaag tatatttttg atttaaaatg tacttacatt taagtctatt actttatttg
      121 gaacaatttg tagaatttca aattccttga cagtaataag taagtaattg tataatcaaa
      181 ctgcaatata ttaataatat tagtgaaaat gaaaggatat aaaatatgta taaatcagaa
      241 aatttttcaa aaaaatctgt attaataaat tcatttttaa gtaaattttt aaaaataatt
      301 ggatggggtt tagtaagttt atttacatta tcagcattag tactttcaac tatttccatt
      361 ataatcggat gggctgtaat acttcctatc caagtatgtg cagtattttt aattatagga
      421 ggagtttgta tttttaaagg taagaggtta ggagaccaaa tttctcgtta taaaaaatat
      481 tgtacaatta taaacaatag aaatattatt ccagtagaac ttattgcaga aaatacatct
      541 aaatcattaa attttataat aaaagatgta caaaagatga tagacaaaaa ttactttata
      601 aatacttaca ttgataaaag aaataatcag attgtactga caaatgaaga ttttgttcca
      661 acaagatatg aagatgtagc atatgaagtt aaagaagaag aaaagactga tgaagacaat
      721 gaagttgata caattataaa taaaggaatg aattatctaa cacatataaa agaagctaat
      781 aaaaatatta aatcagaatc aatgtgcgat aaaattgtac aagtagaaga tgttacaagt
      841 aaaatatttg atgttgtaaa acatgaccca tcaaaactta ctcaaataca aaaatttatg
      901 gattattatc ttccaactac tttgaagcta ttaaattcat atcatacatt ggaagaacaa
      961 ggcattgata gagaaaatat aacaacaact atggaaagta ttgaaaatac aatgaatacg
     1021 attgtagtag cttttgaaaa tcaattggac tacctgtttg aagatgaagc aattgatatt
     1081 tctacagata ttactgtttt agagaatatg ttagttcaag aaggattaac gagtggtaaa
     1141 ttttaacttc aatagaaaaa atattctgtt atttttaaac aattaattag tcataaagta
     1201 taaaatatgt gttagataag ttaagcagta ctttatgaag gaagaggaga gaaagatata
     1261 atgaataatt tagatgatat accagttatg ccaactttga cgcttgaccc atttggagaa
     1321 gaatcaaaca ctagtgatat agataattct gacttattaa tgaaaaagga tgaaaaagac
     1381 ccagaagaag aaaagctgtc tgaatctgaa cgtaagatgg taaaggaatt tgcggaaaaa
     1441 atagatatta caaatacaaa tatgatttta caatatggag ctggtgctca aaaaaaggtg
     1501 gcgagctttt ctgaaacagc tttaaagagt gtcaaaacaa gagatttagg agaagttgga
     1561 gatatgctta caaatctagt tactgattta aaagcatttt cagcagatga aaaagaacaa
     1621 agtggttttt tgggaatttt taaaaaggca aataataaaa tttcaaatct aaaaactaag
     1681 tatgatagtg cagaggtaaa tgtagataaa gtaagcaaag aacttcaaaa gcatcaggtt
     1741 aaaatattga aagatatagc aatgcttgat aagatgtatg agttgaactt agcttattca
     1801 aaagaactta ctatgtatat tatagccgga aaacaaaaac taaaagatat gaaagaatat
     1861 gagatgccaa agttgagaga aaaagctcgt ttatctggtt caacagaaga tgctcaatct
     1921 gtaaatgata tggtttcact ttgtgacaga tttgaaaaga agattcatga cttagaatta
     1981 actagaatgg tatcgcttca aatggcgccg cagataagat tggttcaaaa tagtaataat
     2041 ctgatggcag aaaagattca atcaactata gtaaatacta ttccattatg gaaaaatcaa
     2101 atagtacttg ctcttggaat ttctcattta aatcaagcta tgaaagcaca gcgtgaagtt
     2161 agcaatatga caaatgagct tttattaaag aatgcagaaa ctttgaagat gggaacaata
     2221 gaaacagcaa aagaatcaga aagaggaatt gtagatatag atacaattaa gaaaactaat
     2281 caatctttaa tatctactat tgatgaggtc gttaagatac aacatgatgg tagaataaag
     2341 agacaagaag cagaagttga attatcaaaa atagaaaatg aacttaaaag taagcttctt
     2401 gaatttacag ttaaataaaa attatactaa gataaaaaag agactatccc aaaatagaga
     2461 taagtctctt tttcattgtt taaatgatta aagtatatac ttatattata aatttctatt
     2521 atcttttaac ataacatcat gagccccacc ttcaactata ctagtagaag atacaagcgt
     2581 aagtttagca tttttttgaa gttcaggaat actaagtgct ccacagttac acatagtaga
     2641 acgaacttta cttaaagaaa gagttacgtt gtcttttaaa gaaccagcat aaggcacata
     2701 agaatcaaca ccttcttcaa aagaaagttt cttatctcca ccaaggtcat atctttgcca
     2761 gtttctagca cgagcagaac cttctcccca atattctttc atgtaactac catttatatt
     2821 aactttgtta gttggactct catcaaagcg agagaagtat ctaccaagca ttataaaatc
     2881 tgcacccata gctaaagcta gagttatatg atggtcataa acgataccac catcagaaca
     2941 aattggaata taaatacctg ttttttcaaa gtattcatct ctagcttgag caacttcgat
     3001 tatagaagta gcttgtccac gtcctatacc tttttgttca cgagttatac atatagaacc
     3061 accaccaata ccaactttaa cgaagtcagc accagcttca gctaggtaaa ggaatccttc
     3121 acggtcaact acatttccag ctcccacttt aactgtatca ccatattttt cacgaatgaa
     3181 atcaagagtt attttttgcc actcagaaaa accttctgaa gaatctatac ataaaacatc
     3241 agcaccagct tcaactaaag caggaacacg ttcagcaaag tctctagtat taataccagc
     3301 tccaactaca tatcttttag aagaatctaa aagttcaagt ggattttctt tatgagaaga
     3361 ataatcttta cggaatacca tgtacataag attaccatta tcatcaagta caggtagaga
     3421 gttaagtttg tggtcccata taatgttgtt tgcttctttt aaagtaacat ctttgttagc
     3481 gtaaactata gatgacatag gagtcataaa ttcactaact ttagtatcta aatccatacg
     3541 acttatacga taatcgcgac ttgcaacaat acctaataat ttaccagttg aagttccatc
     3601 ttcagtaaca gctactgtag aatgtccagt tttttctttt aagtcaagta tgtctttcaa
     3661 tgtgttatca ggtttaatat ttgaatcact tacaacaaaa ccagctttgt gggatttaac
     3721 acgtgccacc atagcagctt cattttcaat agtttgagaa ccgtatataa atgaaatacc
     3781 accttcttta gcaagtgcaa tagccatttt gtcatcagaa acagattgca taatagcaga
     3841 agtcaaaggt atattcatat aaatatctgc ttcctcgccc tttttgaatt tagtaacagg
     3901 tgtttttaaa cttacattag caggtataca atcagtagaa gagaaacctg gtacaagaag
     3961 gtattcactg aaagtatgtg atggtgtatc aaaataaaac gccatttttt aatcactcct
     4021 tatattttta tactttttat aattgatagt attaattata acttattctt taattttatt
     4081 aaagtatttt gtcaaatatt gagatttttg aaaaatttaa actattttaa ttgaatttgt
     4141 ttaatatata ttgccttata gggtaaagtt gtatattaaa taatgtttag tatttaatag
     4201 tagctaattt gaaattaata tttagttatt catacattaa agttgtatat tttatgttga
     4261 taatgtgaac ctagagtgta taaatgtcaa aagtatagat aaattaaatc tatattagta
     4321 tatccaaaag tacccttaat aaatttgttt aattgaatta ttatcgtttt ttctattaaa
     4381 tttaaatatt ttataaaaat agtattattt ataaaactag acaccctaaa atactacata
     4441 aataaaatta aacaaaaact aaaatggcaa atgtcattat ctaaagtgac atagaaacgg
     4501 tttcttaaag ttgttactat aaaatataaa ctttataata aaagtataac aaaagggaat
     4561 catatcgata tagaatataa ttcaaaagga ggcaaaatta tgagtagttc taatcaatcg
     4621 acaataaaga catctataca gcgagtaggg aaatttttaa gtggcatggt aatgccaaat
     4681 ataggagctt ttatagcatg ggggcttata acagcattat ttataccaac aggatggatg
     4741 cctaatgaaa aattgagtac tataggtgac ccaatgataa aatacctttt accactattg
     4801 atagcttata ctggtggtaa agcaatagca ggacaaagag gtggtgtaat aggtgcagca
     4861 gcagctatgg gagtaattgt tggggcagat ataccaatgt ttatcggagc aatgataatg
     4921 ggaccatttg caggatggat aattaagaag tttgataaat ttgtagatgg aaaaatacca
     4981 acaggatttg aaatgctagt aaacaacttt tcaataggta taataggtat gcttcttgca
     5041 atactaggat tttatgcaat tggaccagca atagtagcag gtacagctct tatagaatct
     5101 ggagttcaat ttatagttag caaaagttta ttaccgttag tttcagtatt tatagaacct
     5161 ggaaaagtac tgttcttaaa caatgcaata aatcatggta tattaggacc tataggtata
     5221 gctgaggcaa aagaagcagg taaatctata atgttcttat tagaaagtaa ccctggacca
     5281 ggtttaggag ttctattagc atattggatg tttagtagag gaagtgtaaa acaatcagca
     5341 ccaggagctg taataataca tttctttggt ggtatccatg aaatttattt cccatatatt
     5401 ttaatgaatc cagttttaat attggctaca atagcaggtg gagcagcggg aatactaact
     5461 ttctcaatat taggagctgg acttgtagca gcaccatcac caggaagtat atttgcactt
     5521 atggcactag ctccaaaggg aggattactt ccagtattag caggagttgc agtggcaaca
     5581 gttgtatcat tcttagtggc agcaccattt gttaagagag cttcagcaaa tcaaagtgaa
     5641 gaagacaata cttctttaga agaagctaaa gcaaaagtga gtgatatgaa atctgtaagt
     5701 aagaactcta agaaagatat tgaagaaaaa cagctggaag taaatgaaat taagaagatt
     5761 gtatttgcat gtgatgcagg aatggggtct agtgcaatgg gagcttctag atttaaaaat
     5821 agaataaaaa atttagattt aaatatagaa attacaaatt catctgttga taatcttcca
     5881 gatgatacac aaatagtagt aactcataat acattagttg aaagagttgc taagaacaat
     5941 tcaagtgttg agatagtttc aataaacaat tttttaaatg acccaaattt agatgtacta
     6001 tttaaaagac tagaatctaa ataaaataaa aagtaccact aattaggagt ggataatttg
     6061 aaaaaaaaga agattacatc taggcaaaaa aagataatac taatgatagt agaaaattca
     6121 aagaaaaata ttccaataac tatttctgaa attgcaggga tgttggagtt aagttcaaga
     6181 actgtactta gagatatgtc tggaattgaa aaatggtttg atgaaaatga ttttaacttt
     6241 gtaaaaaaac caggagtagg attgatttta gaggaaagta tagaaaatca aaattttata
     6301 attgaattat tagaagaaga aaaaatagaa aaagaataca gcaaggaaga aagaaattta
     6361 atcatattat caaagctact agtttctaac gagccagtaa agtcttatta ttttgcaaaa
     6421 atattaaagg tatctgaagg ggtattgaat aatgattttg ctttagcaag taaatggctg
     6481 gaaagatttg atattgagct tgttagaaaa ccagggctgg gtgtttactt aaaaggtcaa
     6541 gaaaaaagct ttagagaagc atatgtaaat cttatatatg attcatttaa tgaaaaagaa
     6601 atactagata tggtcagaaa tataagtgaa aatatacaaa cagataaaac aatagaaatt
     6661 ttaagtgaaa atagactttt aaatttaatg gataagtgca taataagaaa agttgaaggt
     6721 acattaacaa agaaactttc agatttagat gtaaatttag ctgatagtgc atatataggt
     6781 cttgtagttc atatttcatt ggctttacag aggataaaaa atggtgaaaa tataactatg
     6841 gataaagaat ttctaaaaga attatctata acagaagagt ttaaattagc taaagaaatc
     6901 gtaaaaggta tggaaataga ttttagcatg gatataccac tagatgaggt tggatatata
     6961 actatgcata taagaggtgc aaagcaaagg tcatcttcaa atcacaatgc tttaaactta
     7021 gatgatatag aagtaatgga tattacaaat aagatgatag atttagctga agatgaattt
     7081 aaaataagtt taaaaaatga cgagaggtta tttaaagacc tagcaaatca cttaggacct
     7141 tctataaata gattgaatat gggattagaa ataagaaatc ctcttttaga tgaaataaaa
     7201 agcaagtatt catatgtcta taatggagtt gaaaagattt ctagaattat aaaagataaa
     7261 ctaagtataa attcaatacc tgaatcagaa ataggatata ttgcaatgca cttcgcatca
     7321 gccatagaaa aaaatcttat gatgtatgct aatataaata ttgttgtggc atgtcccact
     7381 ggaataggta cttcaagatt cctatcaact aagattgaga ataaatttcc taatttaaat
     7441 atacttgaaa ccatctcagc tataaacata gatgaagagt atttaaagga aaaagatgtt
     7501 gatttaattg tgtctacagt tgagttaaat acaagtttaa attatatatg tgtaggtcca
     7561 tttatgagtt tagatgacga acagttaatc aaggaaaaaa taaaatctat agctcaaaat
     7621 aaattaatca atttaaatgt aaaaaatggt actaaaaata agaataaaat atatgcacag
     7681 ataacagaaa gtatgaatat aggaaaagat attcttcaat ttttagagga aattaggttt
     7741 gaaaaatttg aaagtaaaga tttaagtgag cttattgaag actcatcaaa aatatttgca
     7801 aaatctagtg aagatataat atctataaaa gaatctttaa aagaaagatt aaaaatctca
     7861 attccatata tagaagaatc aaaaattcta ttattacatt gtattagtga aagaatagat
     7921 attatgaagt tatcaataat aaagctagag aatagaatca tactagattc aaatgaagaa
     7981 atcgacaatg tagtttttat gttacttcct aaaaattcac caagttatca aagacaaata
     8041 atgagtgaaa taagtggttc attaatagat aatataattt ttacgaataa gataaataaa
     8101 ttctctatag aagagatgat attagaggta aaagatatag tttttaattt ttatacgaac
     8161 agattaaaag catttataga taaataaaat taatattgaa aaggaaggtt gatactatga
     8221 ataaagtatt gaatgagaat aatatatttt tagggttaga tagtgtttca aaggaagaag
     8281 ctataacttt agcaggaaga aagttagttg aaaatggata tgtaaaagaa gaatatatac
     8341 cagcaatgct agaaagagaa aaagtaatga ctacatatat gggaatggga gttgctattc
     8401 cacatggtgt aaacgaagca aaaaaagaaa tattatcttc tggaatagtt atattacaat
     8461 tccctaatgg tatagatttt gatggtgaaa aagcatattt attaatagga atagctggtg
     8521 ttggagatga acatttagaa atactatcta atatagcagt agttttagat gatgacttaa
     8581 cagaaagact aaaaaattca aatgacaaac aagcttttat ggaagctttt gccaactaat
     8641 cttaggagga ctttaaaatg aaaaaggcaa ttcagtttgg agcaggaaat attggaagag
     8701 gttttattgg aggcttatta gttaagtcgg gttatcatgt agtatttgct gatgtaaatg
     8761 aggagatatt aaactcaata aacaaagata aaaaatatac tatacacata agagatgtag
     8821 aatgtataga tgaagtaatt gataatataa gtgcggtttc atctataaaa gaagaaataa
     8881 tagatgagat tgtagaggct gaaataataa ctacagcagt tggaccttta gttttgacta
     8941 aaatagcttc tacaattgca aaaggcataa agaatagaaa agaaaaggga ttaacaagta
     9001 atctaaatat aatagcttgt gaaaatgcaa tatacgcaag ctcttcttta aaagaagagg
     9061 tacttaagta tttaaataag gaagaagtgg aatatttaga gatgtacatt ggttttccaa
     9121 attgttcagt tgatagaata gttcctcctg gtaaaaatga aaatcctctt gatgtaacag
     9181 ttgaaaattt ttatgaatgg aatgttgaaa agcaaggatt taaaggagaa ataccaacta
     9241 tagttggtat gaatttagct gataatctta tggcttatat agaacgtaag ttgtttacac
     9301 taaatacagg tcatgctata acagcgtata taggatattt aaaaggatat aagactatag
     9361 aagaaagtat aaaagataaa tttatctatg acatagtaaa aagtgcaatg gtagaaagcg
     9421 gagaaggatt aattaaaaaa tacaattttg actcagaagc acactataaa tatattgata
     9481 aaattttaaa tagatttaaa aatccatatc ttaatgatga tgtattaaga gttggaaggg
     9541 agccattaag aaaattaagt gataaagata gattgattaa acctttaatg acagcaaaat
     9601 catatgacct atcagttgac aatttgattc ttggaatagg tgcagcgctt cattataata
     9661 atagtgaaga tgctcaaagt gtagagttac aagagttgat aaagtctaat ggggtaaaaa
     9721 aagctgttgc taaaatagcg aatataaata atgatgaaga acttttaaat aatatcgaaa
     9781 aaagttatat atttatggaa aatttataaa tttgcttgaa aaaagttagt tctgataaag
     9841 taagcataac atattattct acacagtttg aattatttgt tgaataatag agaattataa
     9901 tatataatta aaaagaataa attaatatat ttacctgtat atgtttgata atatggttca
     9961 aatgtttcta ctaagctacc attaatagct tgactacagg agtgaagaag atatagttta
    10021 tacttatttt aaattatata ttaagttaat tactttgaat tttaagctcc tgtctatgat
    10081 atagacagga gtttttttat tatcttaata taaaatactt acaagaatag atagcaaagt
    10141 tagagcaaat ataatttttt tattaatata actttagaaa ggattgggtg gaagtttaat
    10201 gaaggcttta caagaaaaga tattgagaga aggcagtgtt tcaggaaatg atatactaaa
    10261 agttgatagc tttttaaatc accaaattga tgtagctttt ttaaatgaaa taggaagaga
    10321 gtttaaagag agatttgaag gagaaaaagt tgataagata tttacaatag aggcttcagg
    10381 aatagctata gcatcaattg tttcacagta ttttgataat gcacctgtag tatttgcaaa
    10441 aaaatcggaa tctaaaaatt tggataaaga tgtatatgaa actaatgtat attcatttac
    10501 taaggcaaga gaatattctg ttaaagtttc taaaaagtac ataaacaaag gtgaaaatat
    10561 actgatagtg gatgatttct tggcaaatgg aagagctgct cttggactta aagatttaat
    10621 tgagcaagca gaggctaact tagttggagt aggaattgtc attgaaaaag gattccaagc
    10681 tggaggagca cttttaaagg ctaataatgt aagattagag tctttggcag tagttgaatc
    10741 tatagataat ggaactgtaa aatttaggta atttatgata ttatatactt gtgtttagca
    10801 catattttaa ctatgtaatt atggaggatt ttttatgaga ttttttatag acacagccaa
    10861 tattgaggaa ataaaagaag caaatgattt aggtgtaata tgtggtgtaa ctaccaatcc
    10921 atctctaata gctaaggaag gtagagattt tatagaagta gttaaagaaa taagtgaaat
    10981 agtagatgga ccaataagtg cagaagtaat aagtttagaa cataaaggta tgatagagga
    11041 agcagaaaaa ttatctaaga tacataaaaa tatagttata aagataccta tgacagcaga
    11101 aggtctaaaa gcagtgaaag tactatcaag taaaggtata aagactaatg taacacttat
    11161 attctctgcg ggacaagctc ttttagctgc tagagctgga gctacatatg taagtccttt
    11221 tgttggtaga ttggatgata tatcacaaaa tggtcttgat ttaattgaag aaatcgttga
    11281 catatttagt gtaaatagca ttgaggctca aataatagtc gctagtgtta gaaatccaat
    11341 acatgtttta caagctgcta gaatgggagc agatatagca acagttcctc ttaaagttat
    11401 aaaccaaatg attaagcatc ctttgacaga caaaggaata gatagcttta tgaaggattg
    11461 ggaaggtgct tctttaaaat tgtaattata aattacgttt tataagtata ttaaagaggt
    11521 tattatggaa attctaagta ataaggctag gctattttgc ctagtcttat tttggtgtat
    11581 aatatattga aacatgttat tgaaatagat taatttttta agtgaggagg cgaaaaatgg
    11641 ataaaatatt aagagagata caaagagaag ataaaaaaaa tccatatact gaccaagaac
    11701 ttgctgaaat gttaaatgta gctaggtctg aagtaatatc agttaggaaa aaaaataata
    11761 ttttagattc aagagaaaga agaaaaaaaa tattaataaa agatatatca aaaattgtaa
    11821 gtgaaaatcc tcaaatgtct gaaagaaaaa taactgaaat attaatagaa aatggatata
    11881 atatatcgag aagtgcagtg tcaaaattat taaaagagga aaatttaaat cagtcaaaga
    11941 gtgggattaa agataaagac ctagcatcat caggaaagta tgtaaaggtg agtaaagttg
    12001 tagaagaaga tggatttgaa gaattgatag gtataaaggg aagcttgaaa gaaaaggtaa
    12061 atctagctaa gtcagcgata atgtatcctc ccaatggcct tcatactata atatatggag
    12121 aaacaggagt aggtaaaagt gaattagcta catgcatgta taaatatgct ataaaaaaca
    12181 acatcaaaga agagaacagt ccatttatag tgtttaactg tgcagattat gcagaaaatc
    12241 ctaacctatt gatagctcaa ctctttggag tagtaaaagg tgcatataca ggagctgatg
    12301 caaatagaga gggtcttgta gaacaagcta ataatggaat attgttttta gatgaaattc
    12361 atagattgcc tgctgctggg caagaaatct tattttcatt aatagataga ggagaattta
    12421 gaagattagg agaaagtagt tctaatagaa aggcaaatgt tctcataata agcgctacaa
    12481 cagaaaatcc agattctaac ttacttcaaa catttagaag acgtatacca atggtaataa
    12541 atttacccaa tatgagtgaa agaccaaagt ctgaaagata tgaaataata ataaagtttt
    12601 ttgaaagaga agcaaagcga gtaaacaaga attttataat aactaaagaa gttatgtgtg
    12661 cacttatgaa ttataagtgt actggaaata taggtcagtt aaaaagtgat atacaagtaa
    12721 cttgtgctag agcttttagt aaatcgatat tttctagcga taaggtaatt atagatttag
    12781 atagtttaag ggattatata aaaagtggat attatgattg taattgtgaa aatgaaaagt
    12841 attctgagtt ttcagttgaa gatatatata tagatattag tgaattggtg agtggaaaaa
    12901 atagaatttt atccgataat gagataagtg agatatataa ttatgcagaa aaagagctta
    12961 aggttttgga aagtaagtgc ttttcagaag aagaattaaa aaatgcattt atagaaaagt
    13021 tagacaagaa gtttaatgct attaaaaaca ataaaaattt atctgataga agaagtcaaa
    13081 tagactgggg aggacaatta aaagagtcta cattggagat aatggataag gtaattgtat
    13141 ttatcaagga gcagtttaag catgtaaatc aaggcttgta tttggctcta gcaattcaca
    13201 ttgagcatgc tataggaagg ataaaagatg gaaaaactat aataaatccg agtttagata
    13261 aaataaaagc atcaatgcca atggaatatg agctatcgag atatataatg ggtatagttg
    13321 aagatttgac acaagtaaca tttccagaag atgagcttgg atatttggct tattatataa
    13381 ataaattttg ttataatgag gaaagtataa aagataaagt taaagtagta atagttacgc
    13441 atggtaaagt tggaattgaa atgtctaaag ttgtaaacca tattttaggt atagaatgta
    13501 caataggtat agaaatagca cttacagatt caccatcaga ggggatagaa catgtattag
    13561 aagagcttca aaagatagag gctcgaaaag gtattctagt tctaattgat atgggttctt
    13621 tggtaattct tggtgatgaa gttgaaaaaa gacttggaat tagatgtaaa actgtaaata
    13681 gagtagatac tttactggca atggaagcag gaaaacttgc aactattgaa ggaaaaagtt
    13741 tagatggtat aatagcagat ttaaagaaaa ataagaatta tgctatgata aatacaaata
    13801 aatttagtta cagaaaaaac gagtatggaa agaaaaatgt aatcattact ttatgcttga
    13861 gtggtgtagg tacagcttta aatttaaaag atcatataga aaaacaaatt aaggaatatg
    13921 atgcttcaat tgaagtaaag ccaattgctt ttttaaataa taatttggaa gacgagttaa
    13981 atgatattga agctgaatat aatattattg ctatctgtgg aactattgat atagattata
    14041 aaaacgtgcc ttttatttct tataatgagg tgcttggtaa aaatggtatt aataaagtat
    14101 tagagcattt aaatagtaaa cagccagctt taaatattga aaatcagttg aataatttaa
    14161 tacatgaaga tttgatttta tacaattttg aaggaatttc aaaggagtat ataattgata
    14221 ctcttgtttc aaagcttgaa gaaggtggat atgttgattc aaagtatata ttaagtgtat
    14281 ataaaagaga agcaatggga agtgtcgtaa tggcctctaa ggtagctgtg ccacatggac
    14341 ttccagaaaa cgttataaag cctgcaatag caattgcaag gttgaataaa cctatagtat
    14401 gggacaataa atttatggtg gatttggtgg tactattggc acttaaagaa aataataaga
    14461 aagaaatacg aagcttattt tcaaaaatta atgaccagca tactttagaa gttttattaa
    14521 atactgaaga taaaaatgaa ataaaagaac ttttaagcta attattagta cagagaagaa
    14581 agacaaaaaa tttgctttag tataaaattt aaaactactt aattgctaag tagttaatta
    14641 ctcgagataa ggctagttct atgaaattta tttatatgat tttatagaat tagctttttt
    14701 cttggtaaat aaaatatatg aatttattta tgcaaaaagt aaattttatt ggacaattct
    14761 atgaaaattt ttttctatat ttcctataaa atatagaata tataaaaaat atgtaaaaat
    14821 aaattaaatt cataataaat aattttataa aatagttgtt aaacataaaa aaccatttat
    14881 aaaaaacaaa aaaatcattt ctctaacaaa aaaaaccaca aaaaatataa aaaagtatgg
    14941 ctagttaagt gattaacaag taaaaattaa aataaaaatc aaaaaaaatt tatcaatgaa
    15001 agtcagctaa aatcctagaa gagagcatta ttttaaggaa aacattttct tttgtttgac
    15061 aaaaaaagcc actttttggc acacaacatg ctttatataa agtcaagaaa aactaaggta
    15121 caagacaaag gcaattagga ggtgtaaata tggagtttat aaattttgta agtgataaag
    15181 ttatagaact taaaatggat tgtaaaacga aagaaaattt ctttaaagaa atacataata
    15241 aagtttttga tttaggcttt gtaaaagaag aatttggaga aaaaatatta gaaagagaaa
    15301 atgtatttcc aacaggatta aatttaggtg attatggagt agccatacca catacagatg
    15361 cagaatatat taaagagcaa tttatagcag tctgtacttt taatgaacca gtagtattta
    15421 gttctatgga agaccaagat gaaaaagtac ctgtaaattt ggctttcgta ttaggactta
    15481 atcaaccaca cagtcaatta tctgtattaa cagaattaat gggaattatg caaaataaag
    15541 agttagttga taagttgatg agttctactg ataaagaaga agttttaaag acactaaagt
    15601 ctttataaaa ataaaaaagt actaaaaata aaaaataaaa attattagga ggaaataaaa
    15661 atgaaaaaaa tattagtagc atgtggagca ggaatagcaa catcaacagt agtttgtgac
    15721 aaggtagaga aattagttaa ggaaaataat atacaagcag aagttataca atgcaaaata
    15781 gctgaatgtg caacaaagca agaaggagca gatttaatag tatcaacaac tatattacca
    15841 acaacttata atataccagc aataaaagca acagcatata taactggagt aaatacagca
    15901 gcattagata aaaaaatatt agatgcttta aaataatcct atcatagata cattgaaata
    15961 atattttata aaacagaaaa aggaggattt ataaatggat aaattattag cagtagtaca
    16021 atacatttta aatatgggac cgacagtaat actaccaata acaattgtag tactaggaat
    16081 gatatttaga attaagttta caaaagcttt aaagtcaggt cttacaatcg gtataggatt
    16141 tgtgggtata aacttagttg taaacctatt aacatcaaca ttagggccag cggctcaagg
    16201 aatggttgaa agattcggac ttaatttaac agtaatcgat gttggttggc caacaacagc
    16261 atcagcaaca tgggcttcac cagttgcacc aatattaata ccagtttgtt tattagtaaa
    16321 cttactatta ttatacttca ataaaacaaa gatattaaac gttgatatat ggaattattg
    16381 gcactttata gtagcaggtg cggttggata tatagtaaca ggaagctatg tttgggctat
    16441 attctgtgca atattaatgg aattattagt actatttatt gcagaaaaga cagcaaaaaa
    16501 tgttcaggag ttttatgatt tagaaggtat agcattacca actggttcaa cagcttcatt
    16561 tgctccactt ggatatttag taggtaaact tgttgaaaaa ataccaggaa taaataaaat
    16621 acaagcagac ccagactcta tacaaaaaag atttggtata tttggagaac caatgatgat
    16681 ggggattata ctaggtataa tacttggagc acttgctgga tatgatgtag caggaatatt
    16741 taatgtaggt atatcaatgg gtgcagtaat gttacttatg cctagaatgg ttagaatatt
    16801 aatggaaggt ttaattccaa tttcagaatc aataagagat ttcttacaag caaaatatgg
    16861 agacagagaa ctttatatag gactagatgc agcagtagca actggacatc cagcagttat
    16921 atcaacagct cttatactag ttcctataac tttactttta gcagttatac taccaggaaa
    16981 caaagtctta ccatttggag acttagcaac aataccattt tatatggcat ttatagtgtg
    17041 ttttagaaaa ggtaatatag ttcaatcagt tataacagga acaatagtaa tagctatatc
    17101 actttatatg gctacaaact ttgcagatgt tcatacacaa ttattacaac aagcaaatat
    17161 gatgccagaa ggaacaacaa tggttacaag tatagataca ggtggaaact tgctaaaatg
    17221 gggaatattg aaattatctc aattagtttc ttcatttgga atattctaat atgtagttaa
    17281 tatagattac tcttttttag taaagtatgc gaaaatttaa tatttagcaa ctactaaaaa
    17341 agagtaatat tttttataaa tttttaaaga atacaaaata caagaggagg agatttatca
    17401 tgaaagcagc agtattacat ggcacaaatg atatgagatt tgaagatata gaaataaaac
    17461 catgtgaaag tgatgaagta aaaataaaag ttatggcagc aggaatatgt gggtcagatc
    17521 ctccaagagt attaaaacat tggaaatatc cagttccagc tataccagga catgagtttt
    17581 ctggagtaat tgctgaagtt ggtaaggatg taaaaaatgt aaaggttgga gatagagtag
    17641 ttgcaattcc ttttatacct tgcaatgaat gtgaatattg taaaagagga ttattttcat
    17701 tatgtgatga ccatggaatg ttaggagcta aaagttttgg agcttttgca gagtatgcaa
    17761 atataaaggc tacaaatgta cttccaatag gagacatgga ctttgaagat gctgccatga
    17821 tagagccact agcagttgct atgcatggag tacttaatat aggtgttcaa gttggagaca
    17881 ctgtagcagt aatgggtagt ggaacaatgg gacagttagt aatacaagga cttaaaatag
    17941 caggagcagg aacaattata gcagtggata tatctgataa taaattaaga gaatcaaagg
    18001 aattaggtgc tgatataata attaatgcta aagatgttaa cccagtagaa aaaataaaag
    18061 aacttactga tggaaaaggt gttgatatag ctcttgaatg tgcaggttca aaaataactc
    18121 aagaacaatg tttacttata actaaaaaga aaagtaagat aggattttta ggaatagcat
    18181 attcagatat aactttatca gaagaagcat ttgaaaatat atttagaaaa gaactagagt
    18241 taaaaggttt ttggaactct tattctgcac cattcccagg acaagaatgg actaagggaa
    18301 tcaatctagt taatgaagga aagataaaat taaaagaaat ggtatctcat agattctcac
    18361 ttgaagatac ttacaaagca tttgaaatga taagagatag aaaagaagaa tttaataaaa
    18421 tattaatttt accacaaggg gttgaaaaat aatgaaggca gtagttaaaa ctaaaccagg
    18481 ttatgataat gtagaagttt tagacgtaga agaaccaaaa gctacaggag acaaggttaa
    18541 aataaaagta gaatatagtg gtatatgtgg ttcagatata cattcattta aaggtgaata
    18601 tgcaaatata aaagccccag taacattagg ccatgaattt tctggaattg ttgtagaagt
    18661 aggagaagat gttaaaaata taaaagtagg agatagagtt acatcagaaa ctacttttgc
    18721 gacttgtgaa aaatgtatat actgtgaaac taaagattat aacttatgcc aaactagaaa
    18781 aggtattggt actcaagtaa atggaagttt tgctgagtat gtactatcaa gagaagaaag
    18841 tatacatgta cttcctgaaa atgtatcttt attatcagca gcccttacag agccactagc
    18901 ttgttgtgtt catgcagctc ttgaaaagac tactatagaa agctctgata cagttttaat
    18961 aataggacca ggaccaattg gtttattatt agctcaagtt gttaaatctc aaggagctac
    19021 agttataatg tctggtgtta caaaagacaa ggaaagatta gaaatagcta aaaatcttgg
    19081 agtagataga actgtaaatg taatggaaga aagtttggca gatgtagtga atgaaatgac
    19141 tgatggaaat ggagtaaaca aaggatttga ttgttctgga tttatgccag cagttaacga
    19201 agctttaaga ttgcttagaa aaaaaggtac tttcgtacaa gttggaatct ttgctaaaaa
    19261 attaaatgaa atggaccaag aagcaataat ccaaagagag ttacaatata taggaagtag
    19321 atctcaaaag ccaagttctt ggattacagc attagattta atggcaagtg gaaaagtaaa
    19381 tacagaagct ttagttacta gaactgttgg tttagacgaa tttaaagaag gtattacagc
    19441 tttaatgaac ggggaagaaa taaaggtagc agtaaaatct taaaaaaaca tttgtattat
    19501 tttaaaaaaa attgtaaaat ctactgtagg ataaaaaatg taagatctta aaaaataaca
    19561 ggaggaagaa agtatgagca ctcttagaga tcattctaat aatattagaa aaaacataat
    19621 aaaaatggtt gcagaagcta aaagcggaca tccaggtggt tcattatcaa tagctgatat
    19681 gttgacagta ttatattttg ataagatgaa cgtatgtgca gaaaatccaa aaatggctga
    19741 tagagataga tttgttctat caaaaggtca tgcagcacca gcactatatg ctacactagc
    19801 agaaaaagga tttttcccag aagaagaatt aataacacta agaaaatttg gttctaagtt
    19861 acaaggtcac ccagacatga aaaaagtagc aggaatcgat atgtctactg gttctcttgg
    19921 acaagggcta tctgcagcaa atggtatggc acttgcagga aaattagaca acaaagacta
    19981 tacagtatat actatattag gtgatggaga aatccaagaa ggtcaaatat gggaagctgc
    20041 aatgacagca tcacattaca aattagataa tttaattgca tttgttgact taaatggatt
    20101 acaaatagat ggttctaatg aagaagtaat gaatgtaaat ccagtagatg acaaattcaa
    20161 atcttttgga tggaatgtaa tggtaataaa tggacattct tttgaagaaa taggaaatgc
    20221 agttgatgaa gctaaaaaag ttacaggaaa accaactgta ataatagcta aaacagtaaa
    20281 aggtaaaggt gtttcattta tggaaaataa tgctgcatgg catggaacag ctccaaatgc
    20341 agaacaagca gagcaagcat tgaaagattt agaaggaggt ctataggaat gggaatagca
    20401 actagagaag cttacggaca agtgttaaaa gaacttgcag aaaataaaga tatagtagta
    20461 ttagatgcag atttaggaaa agccacaaaa agtatatcat ttaaagaagt tgccccagat
    20521 agattttttg atatggggat agcagaaggt gatatgattg gtacagcagc aggtcttgct
    20581 acttgtggaa aaataccttt tgcaagtacg tttgcaatat ttgcagcagg aagaggctat
    20641 gagcaaataa gaaactctgt agcatatcca aatttaaatg ttaaaatagc agctactcat
    20701 gcaggtgtaa cagtaggtga agatggtggt agccatcaag ctatagaaga tatatctcta
    20761 atgagaggta taccaaatat ggttgtatta aatccagcag atgctttaga agcaagacaa
    20821 gctattcttg catctattga ttataatgga cctgtttata taagattagg tagagctgca
    20881 actcctgatg taaacagtga aaattataaa tttgaaatag gaaaaggaac tgttttaaga
    20941 gaaggttctg acataacagt gatagctaca ggaataatgg tagcaaaagc tttagaagca
    21001 gcagaagaac ttgctaagga aggtgtaaat gtagaagttg ttaatatatc tacaataaaa
    21061 ccattagatg aagcattaat aaaagaaact gctaagaaaa ctggaaaagt agttacagca
    21121 gaagaacaca gtataatagg tggtttaggt tcagctgtat gtgaagcttt agcagaaact
    21181 aaagatgtag tagttagaag aattggtgtt aaagatgtat ttggtcaatc aggtacacca
    21241 gctgatttat taaaacacta tggcttaact acagaagata tagtaaaaaa tataaaagaa
    21301 ttgttataga tataaatata tctaaataac aaattgattt gacataaatc aattaaagct
    21361 gtcttaaaaa tagaaagaaa tttctacaat gggacagctt tatttttaca atactttatt
    21421 tttatgataa ttgtaaaata gtataaaaat aatcaaaaaa attatagaaa gaggtgctat
    21481 ttaatgaaaa tatctattgg atgtgaccat ggtggttatg aattaaagga atatataaag
    21541 gaaaacttaa taaataaagg tatagaaatt gaagatgtgg gtacaaattc aaaagaaagc
    21601 gtagatttcc caatatatgc aaaaaaggta agtcaaaatg ttcaaagtaa aaaatctgat
    21661 ttaggtatac tttgttgtgg aacaggaata ggtatgtcta ttgcagcaaa taagtttaaa
    21721 ggaatcagag cagctgttgt ttctgactgt ttttcagcta aggccactag agaacacaat
    21781 aatacaaatg tactttgttt aggggaaaga gttattggaa aaggattagc aatgagaatt
    21841 gttgaagaat ggttaaattc aagttataat ggagaaagac atgcaagaag attacaaatg
    21901 attgatgata tagaaaaaga aaatttataa atatataatt tataataagg gggaacgtta
    21961 tgtctattat ttgtgcttca ataatgtgtg cagaccaaat gaagttaaaa gaggaattag
    22021 aagctcttga agaagcagga gtaaaattac ttcattgtga tgttatggat ggaatatttg
    22081 ttaaaaactt ggctatgggg ccagagttat taaaatcaat aagtgaaaat acaacaatac
    22141 ctttagacat acacttagcc acagaaactc cagataagta tattgatatg atgtcttata
    22201 taaagccaaa atatatttct tttcatgtag aatcaagcac aaatgtaaga gctgatatac
    22261 aaaaattaag aaattatggt atagggccag tattagcaat aagccctcaa acaagtgtgg
    22321 ataaaataga agaatatata ggtttagttg agggtatctt agtaatgaca gtaaatccag
    22381 gatttgcagg tcaaaagttt aatctttctg tattggataa gttggataaa cttacagaga
    22441 tactaaaaga ttatgataat cctccattta tagaggttga tggaaatata aataaggata
    22501 ctattaaact tatgaatggt aaaaaagtag atatatatgt tgttggtact tcagctttat
    22561 ttaatgacaa gcctccaatt tcatataaag ataaaataaa agaactaaaa gaaagtataa
    22621 agtaactatg taataaaatt ataatatgtt tctatttaat ggtaaaattt taggtagaaa
    22681 caagaaattt tgtaatattt aataaaaatt ttggttggat aaggagagtt ttttatggga
    22741 gacctatata aactgcaaaa tggtactgat attagaggaa tagcatatga aaatgattct
    22801 aaagaagtta acctaactgt agaagaagta agaaaaatag ctaaagcgtt tcatatttgg
    22861 ctgaaagaaa agactaagaa agataaagta actgttgcta taggaactga ttctaggata
    22921 acaggaagcc aatttagaag tgctgtcatt gaaactttaa ctaatgatga ttgtaatgta
    22981 attgattgtg agattgcaac aactccagct atgtttatga caactattat ggatggatat
    23041 aattctgatg ggtcgattat gattacagca agccacttac cttattacta taatggttta
    23101 aagtttttta cagaaagtgg aggcttagaa aaagctgata taaaagaaat gttggatata
    23161 gctgataaaa atgatagtgt agactatgag aaagcaaata aaaaaggtaa agttatatca
    23221 aaaaacttaa tagaagatta ttctaattta ttaatagata aaattagaaa aggtgtaaat
    23281 tcaagtaaaa attatgaaaa gcctttttct ggacttaaga tattggttga tgcaggaaat
    23341 ggagctggtg gattctttgc tgaaaaagtt ttacacatac tgggagcaga tacaacaggt
    23401 agtcagtttt tgaacccaga tggtatgttt ccaaatcata tacctaatcc tgaaaataaa
    23461 gaagcaatgg aaagcatatg taaagctgtg ttggacaata agagcgattt aggaataata
    23521 tttgatacag acgtagacag agctgctatt gtaggtaaaa atggaaaacc aataaataaa
    23581 aatgctctta tagctgttat atcatcaata gtattagaag aacatccaaa aacagctata
    23641 gtaacagatt cgattacttc tgagggactt gctaagttta taaatgaatt acaaggaaga
    23701 catcatagat ataaaagagg atataaaaat gtaataaatg aagctataag attaaatagt
    23761 gaaggtgaag agtgccattt agctatagaa acatctggac atgctgcttt aaaagaaaat
    23821 tatttcttag atgatggggc atatttaata gctaaaattt taataaaagt agcaaaacta
    23881 tccttagaag gaaagactat agaagaatta atagaaaacc ttgaagaagc tcgagaagaa
    23941 aaagaagtta gaataggcat taataaagaa gattttagac catatgcaga agatatatta
    24001 aaagatttag attctcatgt taggagtatt gatggatggt ctgtagcacc aaataatttt
    24061 gaaggtataa gagttaattg tgatgaatca aatggagatg gatggttttt acttagaata
    24121 tcactacatg aaccattatt agctttaaat attgaatcaa ataaaattgg tggagcagaa
    24181 caaatttatt ctaagttaaa acttttctta gaaaaatatg atttaagagg tctttagggt
    24241 aaatagaaag aatatattta tatcgaagaa tatatgtaaa tttgtaccta agattacaaa
    24301 tattacaaaa ttgtaatctt aggtaacaga gatgtaactg attatggaaa cactatgtga
    24361 tattataaat acagagagat gaaatacatg ctgaattata gagaaatata atttaaaatg
    24421 tattaatatc acaccaaaaa ggtataatca aaaaatatgt aaatataaac cccaacattt
    24481 agaaaaagac ctcgaaggag gtttttttct tgtttaaata acttaaaata tatttttata
    24541 ttaatgtatc aattaactct tctaaaagta agcattacct taaataaatc agcatctata
    24601 attatttcca tgtctgcatt ttctaattca attatatttt gagcaatgga taaaccaaga
    24661 ccagagccat ctgtttttct agatacatca ccccttctaa atctttctac taactcttct
    24721 ggctttaggt ttagtttatc atttgaaata tttttaaatg ttaatattat attttcttcc
    24781 tttataaaca tatctatata gactctagta ttaggcatag agtattttag tatattgcaa
    24841 attagatttt caaaaactct ccaagttttt tttccatcta tcatggtaaa aacagcatgc
    24901 tcaggtgttt ctattataaa atctaaattg ctattttgaa ttttgtcttc aaactctaca
    24961 atactttgaa ttaaaagttc tcttatatct gtttttgtta tattaaattc tacatctcca
    25021 ctacttagct tagatgcttc aaatatgtca tctattaata attttaatct ttgtgatttt
    25081 ttatctaaaa tatttatata gtcatttaca gtctctttat caaagtcatt attttttaac
    25141 atatcaacat agcttaatat agatgtaagt ggagttttta agtcatgaga tacgtttgtg
    25201 ataagttctg tcttcatcct ttcatttttt atactagaat ctacagcatt ttcaagacca
    25261 tctgttatat tatttatact tttagataag tcagatattt catcatttcc tattacttct
    25321 agcttatact ttaaatctcc attctcaata ttttttacat tctttgatat attatttatg
    25381 taattaaact tagcagataa aaagttgtat atatataaat gaaaaactgt gtttacaagt
    25441 gtaaataaaa ttactatagc tattgcctca gcgtaatata tatacataaa gaatatcaaa
    25501 accatatttt ggataatagc ttgcataact atagatatta aaaatactat agctaatttt
    25561 ttatttatag tttttctatt atacacacta agtaagtttg aaaagaatac atatgttata
    25621 gacatatctt ttagattata gttattatat ttaatatttt catatattat gtagactata
    25681 gatataatta taaaattgta gattattaga ttagtgttgt aaaacatttt attacttgta
    25741 aaggcatgaa accttaaaat taatagtatc aaaattaata taagtgtaag ttctattttt
    25801 accttagaaa aaaggcttat gacattctct aagaatttga ctttagtctg tttatttttt
    25861 ttatacaata taaaacatag tacaatcaat aaaaaacttg ataatataac acctatacag
    25921 acaaactcta attctacttt tgacaaatgt aaaggagtgc caaaaaaata aaaataaggt
    25981 atagtaaact ctttataata ataattaata ttataaaaaa agttattatt caaatcataa
    26041 actgcttcaa ataatataga aattaataga aacagtagta ataataaaat aaattttgct
    26101 ttagaatcat taataattaa gtttttcaat tttgtaacca atgccccaca ccacctttaa
    26161 atattttggt tcttttggat taatttcaat tttttctcta attcttctaa tatgaacagc
    26221 aatagttctc tcacaactat aagcatcctc attccagaca ttttcataaa tctcacgaga
    26281 agagaaaatt ttaccttttc gtgacataag aagagtaagt attttatatt caagtggtgt
    26341 cattttaatt tcttccccat ctaaagaaac tatttttgta tctgtattta gctctagtcc
    26401 accacttttt agaatataat tagtatcatt tgagttattt gtattactaa aatcacctaa
    26461 atttatgtat cttctaagtt gagattttac tctagcagta agttctaatg gattaaatgg
    26521 tttagttata tagtcatcag cacccatatt aagtcctata actttgtcca tatcttctga
    26581 ttttgcagat aagagaatga ttggtatatt tcttttttct cttattttaa gtgtagtttt
    26641 aagcccatct aaattgggca tcattacatc cattattatt aatttaatat cattttcgat
    26701 tagtatatcc aatgcttcaa gtccatcata tgcctttaaa acattaaagt tatcaggttt
    26761 taaatagaat tctatagcat caactatctc tctatcatca tctacaacca atatattttg
    26821 attcaattta ttaacctcct tgaaatttta tttttaacca atctttattt tataccaaaa
    26881 agaagtatta gaaaacagta agcatatttg ttatgaaata aaaactaata cttttaatat
    26941 attgtcaatg catatagtaa tttttaaagc atagatgtat atattaatat gaagttaaaa
    27001 gtttatgaaa atatctagga taatttatca cactccttat gtcattttat gtttattaat
    27061 tttttaggtc taaacatata ctaacaaata taaataacaa atgagtttca taattattaa
    27121 gaatttataa caaatattta ttttgatgta ttttaatata aataggtagt ttaatgtaga
    27181 tatgcataaa acctttaaga agaaaactta taggtttcaa taataatatt tttatatatt
    27241 ttaagacatg atgaatctag atatggggaa tagttggatg agaaaaagta gtatagcaca
    27301 aaaaagtgct atatcacaat ctcaaataat ttacttttta taatttaagc taaaagaata
    27361 aatatttctt ataaattagg tgtatgaagt atggcaggaa catctttatt ccttaataat
    27421 ttatcaaaag atttatgatc agatttataa ccaatacctt ctctatcttc taactcatca
    27481 acaattttgt attgttgaca ggcatttttt accttttcat agtcttcagt agaatgagct
    27541 ttataaacta ttttattatt aaaagttatt ttatcagcaa attttggttt tacaaaatat
    27601 ttggcatctt ttattttacc agcattatat aaattttgta taacagaacc attttttaaa
    27661 tgttgcaaat ggtcgtctaa cttataagta tgtgctatat gagttacatt tttaaaattt
    27721 tcttcaaagt taatggcaat tttttccatg taattgaagt cagtattacc atttgtattt
    27781 gtttctggta ataatattat attctccctc cttacaccaa ggctattaag agaagctaaa
    27841 aattctctgt ttctatattc tgatttttgt atatctgtta gattttcata ctttttatat
    27901 ttatcaaata cagatatgcc acatccagta gataccaaaa ccacaaatac atgatttttt
    27961 cctctttctt ttatagcatt aacaatagca ctcccagccc acaacacttc atcatcttga
    28021 tgttgaacat agaagacaac ataatcttta aattttttat gactataatt catatagctg
    28081 ctaaaagcag ttaaaatcaa gcataaagct agaatgatag ataaaattct atatttactt
    28141 atagtaaatt ttttattctt aaatgtcatt taatcatctc ctgaaaagtt gtcttagtta
    28201 tattatcaaa caaagtgcta aaaattattt cttaaatact gaaaaatata gagtagatta
    28261 atggaataaa atttttttat taatttaaaa ttaagaaaat atttatgtat aaaaccaatc
    28321 aaaatattaa ttagtgatag gaattgagat ttaaagggat tgtacattta tttgagattc
    28381 atttatatag cattacttta gtattgagaa taaaagtaat aactatttaa atttaaagag
    28441 tacacattga tatttgtgta ctctttaatg atgtgattgc ttatttacta caaaaacata
    28501 gtctttttaa ac
//
LOCUS       DBGJFK010000046        28370 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.046, whole genome shotgun sequence.
ACCESSION   DBGJFK010000046 DBGJFK010000000
VERSION     DBGJFK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28370
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.046"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            220..441
                     /locus_tag="ACOIAP_002339"
     CDS             220..441
                     /locus_tag="ACOIAP_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HGZ2639221.1"
                     /translation="MGYLKEDRQDYCCEFARPYVNRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            441..704
                     /locus_tag="ACOIAP_002340"
     CDS             441..704
                     /locus_tag="ACOIAP_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HGZ2639222.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESRYGALTNFGYESSEHPWSWISEPWPWDKSFYK"
     gene            768..1340
                     /locus_tag="ACOIAP_002341"
     CDS             768..1340
                     /locus_tag="ACOIAP_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HGZ2639223.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGSCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            2132..2785
                     /locus_tag="ACOIAP_002342"
     CDS             2132..2785
                     /locus_tag="ACOIAP_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HGZ2639224.1"
                     /translation="MNFIYSNAEIEYLKHKDKILSDIIDKIGHIEREIDTDLFSSVIH
                     HIIGQQISTKAQATIWKRMKEHLKEINASSILSAGTTGLQSFGMTYRKAEYLTDFATK
                     IQNGEFDLQSITYMSDKEAIDKLTSLKGIGVWTAEMILLFCLQRPNIFSFDDLAIQRG
                     LRMVYHHRKITRKMFEKYQKRFSPYCSVASLYLWAVAGGVIDGMRDYAPKGKVRKNG"
     gene            2947..3480
                     /locus_tag="ACOIAP_002343"
     CDS             2947..3480
                     /locus_tag="ACOIAP_002343"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGZ2639225.1"
                     /translation="MQYINYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGEEPNFTPSLHMVGTPFQTAVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNRSLTGYAGGIDRKIKLLSL
                     EKVSMQHYFIPKKGSAL"
     gene            complement(4034..4819)
                     /locus_tag="ACOIAP_002344"
     CDS             complement(4034..4819)
                     /locus_tag="ACOIAP_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HGZ2639226.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQGNIGDMQGSI
                     SGIEGTISGMQGTISDMQGNIGDMQGSISGIEGTISDMQGNIGDMQGSISGIEGTISS
                     VQGTIIDMQGTISDMQGNIGDMQGSISGIEGTISGMQGNIGDMQGSISGIEVTISGMQ
                     GNIGDMQGEIKGVNSRLDNMEPNIKDLKTGQVETSSKLNTIQSDVTEIKSDVKINRNT
                     LDTIIKHTSSLVEDTSDIKNDLNNIEIVTSKNWNDIAKLKSVK"
     gene            5283..5696
                     /locus_tag="ACOIAP_002345"
     CDS             5283..5696
                     /locus_tag="ACOIAP_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HGZ2639227.1"
                     /translation="MKMPKENVDMIMFAPCGMNCIVCYKHCYHKKPCAGCLNSNMGKP
                     EHCRKCKIKDCVCQKGLFYCFECFDFPCKLIKNLEKSYNKRYQVSLLENSKFVQKYGL
                     EKFMEKQRERYTCSKCGGIISIQDRECSECREKMK"
     gene            5770..6306
                     /locus_tag="ACOIAP_002346"
     CDS             5770..6306
                     /locus_tag="ACOIAP_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HGZ2639228.1"
                     /translation="MIGLKCGMVKLLKHQIIWDKSAKDVIILLKSILDKTAIDIQHIG
                     SSSIPSVSAKPIIDIVVGVASLEEAKLYIKKLEQRKIIFRGQDIPEQLLFVMGDLKKN
                     IRTHHIHVVEWNSFAWNNYINFRDYLNTFTEKAKLYDSNKQKLALQFEDNRKIYTQRK
                     QELISTLLEEARLWRMNT"
     gene            6467..8041
                     /locus_tag="ACOIAP_002347"
     CDS             6467..8041
                     /locus_tag="ACOIAP_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HGZ2639229.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     QFDIGNVLPQDYYGLIVILGVILGVMGAFYNWFTLYVQYLYKKIPKIGTFGKLLIPFI
                     MAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGSGAPGGIFF
                     PLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTGIILIFEMT
                     GSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGEKILDQFSV
                     MFGSPVANKAIQDIQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMTDERDSGAV
                     YDKMENLCKEHTSHIF"
     gene            complement(8730..9302)
                     /locus_tag="ACOIAP_002348"
     CDS             complement(8730..9302)
                     /locus_tag="ACOIAP_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea carboxylase-associated family protein"
                     /protein_id="HGZ2639230.1"
                     /translation="MEYIINPCSGIKIKVTKGQKIEIVDIEGGQVVDFFAEMQDDSAE
                     FISPGVTIDCNESLRLQVGNLMYSNKYKPMFKILYDDVREHDLLHPCCKLEMYDFFYN
                     NGENHPNCFDNINQALGTSHQIIHPINLFMYTKLNTDGSIEVCEPLSKANDKIVLEAL
                     ENMTLGIAACSVSESSCNSRKCTSIKIVVD"
     gene            9706..10275
                     /locus_tag="ACOIAP_002349"
     CDS             9706..10275
                     /locus_tag="ACOIAP_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HGZ2639231.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTEILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESSGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPSVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKMLYSNRYN"
     gene            complement(10612..11448)
                     /locus_tag="ACOIAP_002350"
     CDS             complement(10612..11448)
                     /locus_tag="ACOIAP_002350"
                     /inference="COORDINATES: protein motif:HMM:NF025854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGZ2639232.1"
                     /translation="MVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLSYGTYLIIL
                     SAILANIGVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQ
                     MIESYLEIEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVH
                     FNIDIDNHLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLT
                     NNKVNPINRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIR
                     LF"
     gene            complement(12180..12356)
                     /locus_tag="ACOIAP_002351"
     CDS             complement(12180..12356)
                     /locus_tag="ACOIAP_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639233.1"
                     /translation="MFFTFIGVISAILLLCTIIYGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(12460..13041)
                     /locus_tag="ACOIAP_002352"
     CDS             complement(12460..13041)
                     /locus_tag="ACOIAP_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2639234.1"
                     /translation="MKADSTKEQLINATIQLLSSHRDVSSITAREIVAKANVNLAMIN
                     YYFKSKEELINTSIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFDFIGEHSQFI
                     KISVPYILIQEEIVYPFEILPLIKAHYENHNNKKTEAEYRTIAYQITSFIQLIFLRSN
                     AFLKYSGIDILNVEQRNGLIDFQLDLFLVDITK"
     gene            complement(13164..13988)
                     /locus_tag="ACOIAP_002353"
     CDS             complement(13164..13988)
                     /locus_tag="ACOIAP_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2639235.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISTLQRIVLLRDSKFSIAEIANIIHDWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISIREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQPNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHRGEHNEINCENYLTEIQIPLIQV"
     gene            complement(14154..15047)
                     /locus_tag="ACOIAP_002354"
     CDS             complement(14154..15047)
                     /locus_tag="ACOIAP_002354"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGZ2639236.1"
                     /translation="MQLYNTPFNTNKNLIYFFTLTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEMGIKWPLLTILFFALTFIT
                     SLTIGNYFNVKTSDIDWRQIVILRPSQIAYMLLVSFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFSVQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDL"
     gene            complement(15301..15738)
                     /locus_tag="ACOIAP_002355"
     CDS             complement(15301..15738)
                     /locus_tag="ACOIAP_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGZ2639237.1"
                     /translation="MKIHVEQGINCDDIEITIKCSTLDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLRNNEKVIINRCYIKNIKEKLNI"
     gene            complement(15995..16144)
                     /locus_tag="ACOIAP_002356"
     CDS             complement(15995..16144)
                     /locus_tag="ACOIAP_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HGZ2639238.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LLFKK"
     gene            complement(16149..16388)
                     /locus_tag="ACOIAP_002357"
     CDS             complement(16149..16388)
                     /locus_tag="ACOIAP_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HGZ2639239.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIRIGG"
     gene            complement(16713..16934)
                     /locus_tag="ACOIAP_002358"
     CDS             complement(16713..16934)
                     /locus_tag="ACOIAP_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HGZ2639240.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVIKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            17513..17770
                     /locus_tag="ACOIAP_002359"
     CDS             17513..17770
                     /locus_tag="ACOIAP_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HGZ2639241.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVTKLYGGTNTYIPTYNGL
                     FRYARNREIVKQFNGVNYNELAIRYNMCVSNIKRILNENSV"
     gene            18218..19456
                     /locus_tag="ACOIAP_002360"
     CDS             18218..19456
                     /locus_tag="ACOIAP_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HGZ2639242.1"
                     /translation="MNNGFYKLNSAVLNFDIKSDVNKIRFNHYIMRKENIQRLQGTLP
                     RGQFYMTVRRAATDLQLSISTISRLVREFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKHMELDCVCNDEFVDNSDIELDCNSKDNSFNGDINVETEYCSNEYLFNNDVE
                     HNYDNFYNKDTIKNKSIFNISTIKKYINESFDTNKSENSNLQQESINFNFNDTCNAID
                     KRTNNSIKSNQNKKAMKLSDINVLSDKDITNKKNYFNHTHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNIHPCKEGNSNDSSNYIHSNYTTYDD
                     SVRERKKYENVRYWNPICEI"
     gene            19925..21226
                     /locus_tag="ACOIAP_002361"
     CDS             19925..21226
                     /locus_tag="ACOIAP_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGZ2639243.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDKKSLAIKTSDVTNIITWGQNFGLDGHIKILKENLA
                     RRSINQTCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKVD
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            21302..21577
                     /locus_tag="ACOIAP_002362"
     CDS             21302..21577
                     /locus_tag="ACOIAP_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HGZ2639244.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELIIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            22635..22865
                     /locus_tag="ACOIAP_002363"
     CDS             22635..22865
                     /locus_tag="ACOIAP_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639245.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            22858..23439
                     /locus_tag="ACOIAP_002364"
     CDS             22858..23439
                     /locus_tag="ACOIAP_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2639246.1"
                     /translation="MNNKKHWYDYLWIFSSVYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMMLFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(24013..24690)
                     /locus_tag="ACOIAP_002365"
     CDS             complement(24013..24690)
                     /locus_tag="ACOIAP_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGZ2639247.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTIRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            25221..25742
                     /locus_tag="ACOIAP_002366"
     CDS             25221..25742
                     /locus_tag="ACOIAP_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGZ2639248.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKEVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQSL
                     ETWINSLKDNMGN"
     gene            26125..26922
                     /locus_tag="ACOIAP_002367"
     CDS             26125..26922
                     /locus_tag="ACOIAP_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2639249.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKRVVLIGQSAGGF
                     VAQSFIVKYPNMVEGIMMIGTCPYGIDYYSKLDIFWLKQTEWMLKLFPDRLLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGLIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            27302..28192
                     /locus_tag="ACOIAP_002368"
     CDS             27302..28192
                     /locus_tag="ACOIAP_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGZ2639250.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKKAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDGCEKLLREECARYGILTD
                     MKEIIKAYKRSESYTQIKFF"
BASE COUNT        10585 a         3276 c         4598 g         9911 t
ORIGIN      
        1 aattaagtta taaaaaattg tataaactct atattactca tttaaaatag atatttatga
       61 aagattaatt agaaaatttt agaggtaaaa taagaacaaa aaaatactta tttaatctta
      121 ttaaagacct attaaaacta ctgattataa tatagaacaa gtatacaatt tttaagaata
      181 atgctatttt aaaattctaa aaattaagga ggataattaa tgggatattt aaaagaggat
      241 agacaagatt attgttgtga gtttgctaga ccatatgtca atcgtcaaat ttatgatgac
      301 acatacaatc caaaaacagc attaaaaaga ggtactttat ttcctgaatt agatttaata
      361 gagtcaaata actataatga ttggctatat gcaaatccta aaaatagagt tagagctaaa
      421 aaagggggta acatgtacta atgtcattaa atagaagaga acttttagag agaatttcag
      481 aatatcaatt tgcttgtata gaattaaatt tatatttaga taacaaccca agggataaga
      541 aagctcttga ttcatataac agatactgcg ataaatttac acaagctgtg tgtgattatg
      601 aatctagata tggagcatta actaattttg gatatgaatc aagtgaacat ccttggtcat
      661 ggatatctga accttggcca tgggataaat cattttataa ataaaattat taagatttaa
      721 aattagaatt tattattaaa taatatatta aggaggagta agataatatg tggatttatc
      781 aaaaaacact ggaacatcca gttaacataa gacaagcaga ccctagaatg gcaaaatata
      841 tcatgactca gttgggaggg cctaatggtg agctggcagc tgcaactaga tatcttcaac
      901 aaagatatac tatgccaact ggaaaatctc gcgcactttt aactgatata ggtacagagg
      961 aaatggctca tgttgagata atttcttcag tgttatatca attaataggc agttgtactc
     1021 cagaagaact taaggctgct ggacttggca gtaattatgc taattttgga catggtcttc
     1081 agccagtaga ttctaatgga gtaaatttta ctacaagtta tattaatgtc tttggcgatt
     1141 cggtaactga tttacatgag gatatggctg ctgaacaaaa agcattggct acgtactatc
     1201 aattaataaa tttaactgat gaccccgatt taaaagatat attgagattt ttgggtgaaa
     1261 gagaagtcgt tcattatcaa agatttggtg aagcactaat ggatgtttac gagtttacag
     1321 agtgtaagca tcaattctaa tgaactatta aaagttgaca gagagtaagc cttagtttta
     1381 atgaactatt aaaagtgaac cagagagtaa gcattaattc taatgaacta ttaaaaataa
     1441 gaggtaaagg ttttagttga tttcctttat ctcttatttt ttactgatta aacagattac
     1501 tttgctattt aaacatatta ttttatcaaa gaaaagctca atcaaaaatt caaagcatca
     1561 ccatagttca aggtattacc gttgttggca agttttctac aatatgtttt ctttaaaaca
     1621 tttactaaaa taacttattt gatgaaaaac aatttttata gcagtattac ttattagctc
     1681 atttgtacat tttagaaatt gagtttcttt taataagcga aactgagtaa aatacttatg
     1741 gggtgtaata tttagactta gtttaaagca tatggagtac tatgatttac ttatattaac
     1801 actgtttgat aagcatttca aagttaagtt ttcacaatag tgtttctaaa tataacgtaa
     1861 aattttttgc atacagatat taactgtatt ttgtatttta ttagtggcaa aacaatattt
     1921 tttatcataa taagccaaat ggaacaaata gaaactgatg tttcatacat ataaagttca
     1981 ttttttcttt ttcacagcct attcttactt cctacatttg agagtattat aatattattt
     2041 gatgttatat cgatattttt ttgacctatt tagtgataaa attataatat gagcttatct
     2101 aaaagttaat atagtaggag ggctatgata tatgaatttt atatatagta atgctgaaat
     2161 agagtattta aaacataagg ataaaatctt gagtgatata atagataaaa tcggtcatat
     2221 agagcgtgaa atagatacag acttattttc gtcagtaata catcacatta ttggacaaca
     2281 aatatcaaca aaggcacagg ctactatatg gaaaagaatg aaagaacatt taaaagagat
     2341 aaatgcaagc tccatcttat ctgctggtac tacaggattg cagtcttttg gtatgacata
     2401 tcgtaaagcc gaatatttaa cagattttgc tactaaaatc caaaatggtg aatttgattt
     2461 acaaagtatc acttacatgt ctgataaaga agcaattgat aaattgacct cattaaaagg
     2521 tattggggtt tggacagcag aaatgatttt attgttctgc ttacagcgtc caaatatttt
     2581 cagttttgat gatttagcaa ttcaaagagg attacgaatg gtttatcatc acagaaaaat
     2641 tactagaaag atgtttgaaa agtaccaaaa aagatttagc ccttattgta gtgttgcaag
     2701 tttgtatctt tgggcagttg caggtggggt gatagatgga atgagagatt acgctcccaa
     2761 aggtaaagtg agaaaaaatg gttgaatata tgcaggtaaa gataaaacta gtatgatatg
     2821 aggatagata ttataacgaa agtgcaatca ggaggaaatt atactagtat gtttttacat
     2881 aatggcaggt agaaaagaag tgtctaatga ctcgaatgaa attttcagaa tataaggagg
     2941 cattgtatgc aatatattaa ctattaccat agtccaattg gaaatattct tttagcatca
     3001 gataatattg gattaactgg tctttggttt gagaatcaaa agtattatgc ttataatctt
     3061 gaccaagaac atcaggaaaa agaattgcct attttcgagc agacaaagaa atggctagat
     3121 atttattttt caggagaaga acccaatttt acaccatcac tccatatggt aggtactcct
     3181 tttcagactg cagtgtggaa gattttacaa caaataccat atggtaaaac aatcacttat
     3241 ggagaaatcg catataaagt tgctcaacaa aaaggaatat ctaaaatgtc agcacaggca
     3301 attggtggtg cagtagggca taatggaatc tctattattg ttccatgtca tcgtgttgta
     3361 ggaacaaaca ggagtttgac aggatatgct ggtggaatcg atagaaaaat aaaattgtta
     3421 tctttagaaa aagtgtctat gcaacattat tttatcccaa agaaagggag tgcattataa
     3481 agtcatcaaa tttagaaatt cttaatcatt cctttgatat acaagtatct gattttgaaa
     3541 gcaataactt gcaatttaaa aaaagatttt ttagactata tgttatacaa tattatccat
     3601 agtaaacatt atacaatttt agagataggt tttggagttt ttattttatc attgtacaaa
     3661 tgttcaaaat atgtttttgg aaatgataag agtgttaaat ccaaaggaaa aaatgaaaac
     3721 aagattttat ccttttataa gtgataaggg tatgtgtttt aatcaaagat ggacttttac
     3781 tttaatgcta aaaattatat agccatatta taatatataa gggagaggca caccttttta
     3841 gtgttcaatc tcccttgttt tttattatta tatcaagact cattcagtcg tgttaatttt
     3901 atgataaaat gagtattttt taataaatta tttataagta aagtgtgtta tcggataatc
     3961 agtatttttg tataaaattt ggtataaatt taaagaagta tgtgaaattt tcaggtgttt
     4021 ttactatagt atattatttt actgatttta atttagcaat atcattccaa ttcttagatg
     4081 taactatctc tatattgttt aaatcatttt taatatctga tgtatcttct actaatgaag
     4141 aggtatgttt aattattgta tctaatgtat ttctgttaat ttttacatct gacttaattt
     4201 ctgtaacatc actctgaatt gtattaagtt tactactagt ttcaacttgt ccagttttta
     4261 agtctttaat attgggttcc atattgtcta atctactatt gactccttta atttctcctt
     4321 gcatatcacc aatattacct tgcatgccac taatagtgac ttctatacca ctgatactgc
     4381 cttgcatatc gccaatatta ccttgcatgc cgctaatagt gccttctata ccactgatac
     4441 tgccttgcat atcgccaata ttaccttgca tatcgctgat agtaccttgc atatcgatga
     4501 tagtaccttg cacgctgcta atagtgccct ctataccact gatactgcct tgcatatcgc
     4561 caatattacc ttgcatatcg ctaatagtgc cctctatacc actgatactg ccttgcatat
     4621 cgccaatatt accttgcata tcgctgatag taccttgcat gccgctaata gtgccttcta
     4681 taccactgat actgccttgc atatcgccaa tattaccttg catatcgctg atagtgcctt
     4741 ctataccact gatactgcct tgcatattac taatattacc ttgcatttcc tgcaataact
     4801 ctaatatctt ttcatccatc actatcacac tcctatttta ttattataac ataatttagg
     4861 agttgtattc cacaaacgct atatcatatt taatttttaa tcatatcatt atctaatact
     4921 caaaacatgg ttaaatatgt ttatattgaa aactttttta ttaatgaacc ttatattgtc
     4981 taagtgtcta atatactatg ataagtgctt ttgaggtatg tgtggttaca tctgtattta
     5041 aagttgctgg tactatcata tacttttaaa taccacttaa gctatttata ttgattactt
     5101 gtgtttgaat attttgatta gtagatttac ttttatcttt ttttattctt agttttaaac
     5161 tttcatattt ccttgaaaat ttattgacaa ttaaagtgca tgaatttttt agttactttt
     5221 tatgttacaa tatgaatata taacaattcg acaaattgga tttttgaaag gagtaaaatg
     5281 ttatgaaaat gccaaaagag aatgttgata tgattatgtt tgctccttgt ggaatgaatt
     5341 gtattgtttg ttataagcat tgttatcaca aaaagccatg tgctggttgt ttgaacagca
     5401 atatgggaaa gccagagcac tgccgtaagt gtaaaataaa ggattgtgtt tgtcaaaaag
     5461 gattgtttta ttgttttgaa tgttttgatt ttccttgtaa actcataaaa aatcttgaaa
     5521 aaagttataa caagagatat caggtaagcc ttttggaaaa tagtaaattt gttcagaagt
     5581 atggtttaga gaagtttatg gaaaagcaga gggagagata cacttgttct aaatgtggag
     5641 gaattatatc tattcaagat agggaatgta gcgagtgtcg agaaaaaatg aaatagctaa
     5701 atacctgttt atcaaaatag aaaaaattgt agtatgtata taaaggttga ttatgttgag
     5761 gtggttatag tgataggttt aaaatgtggt atggttaaat tattgaaaca tcagataata
     5821 tgggataaga gtgcaaaaga tgtaattata ttgttgaaaa gtatattgga taagactgct
     5881 attgatattc agcatattgg aagtagctct attcccagtg ttagtgcaaa gcctattatt
     5941 gatattgttg taggtgttgc ttctttggaa gaagctaaat tatacatcaa aaagttagag
     6001 caacgtaaaa ttatttttcg aggtcaggat ataccagaac aattactttt tgttatggga
     6061 gatttaaaaa aaaatattcg tactcaccat attcatgttg ttgaatggaa tagttttgca
     6121 tggaataatt atatcaattt tcgagattat ctaaacactt ttacagaaaa agcaaaactc
     6181 tatgatagta ataaacaaaa attagcatta caatttgagg ataatcgaaa aatctataca
     6241 cagagaaaac aagaactaat aagtactttg ctggaagaag cacgactgtg gagaatgaat
     6301 acttaaaaag aataaattcc aatttactga gaaatttaac gataattttc ttatacttag
     6361 taaataaaaa tctatctttg gtgattaaaa aatagctgta aacactcgtg actttggtca
     6421 tgggaaattt agattgttta gaattattgg atgaaggagg aaacgtatga aaaaggatac
     6481 atctcatatt ataaaacggg cagagcactt tcaggtaatt ttgattggag aaggacttat
     6541 ggttggtgct gtggctggtt tgattgtgct tttatacagg atacttttag ggcaggctgg
     6601 tacttggctt agccaaattt taaaatttgt agaaggttct acaataaaaa taatagcttg
     6661 gtttgcagtg cttgcagtac ttgcatggat tgtatcaaag ttggtggact gggaaccaat
     6721 gatttctgga agtggtatac ctcagcttga gggtgaaatg acagggaaaa taaaacaagt
     6781 atggtggcga gtgttgccaa caaaatttat tgggggattc ttgtcactta tgggtggtct
     6841 tgctttggga agggaaggtc cttccattca gcttggtgct atggcaggta aaggtatttc
     6901 tagagcactt gaccgaggaa agaccgagga aaaattcctg ttaacctgtg gagcaagtgc
     6961 tggattatca gcagcctttc atgcaccact ggcaggtgtt atgttttcac ttgaagaagt
     7021 ccataaaaac ttctcagtat ctgttttaat ttctgtaatg acagcatctt tgacagcaga
     7081 ctatatttca gccaatttcc taggaatgga gtctgtattc caatttgata ttggaaatgt
     7141 attgccacag gattattatg gattaatagt gattttaggt gttattcttg gagttatggg
     7201 agcattttat aattggttta ctctatatgt gcagtattta tataagaaga ttcctaaaat
     7261 tggtacgttt ggaaaactac tgattccatt tataatggct ggtattcttg ggcttgttat
     7321 gcctgatgtg ctgggtagtg gacacaattt agttgaagaa cttacaagtc atgaatatat
     7381 ttttggaatg gttgttttga tttttgtcat acgttttata ttttcagctg taagttttgg
     7441 gtcaggtgca ccagggggaa tcttttttcc actacttgtt ttaggtgcat ttataggtgg
     7501 aatatttggt atggtaggtg ttaaagtttt tggaatgaat ccagattatg taaataactt
     7561 tgtgcttttg gctatggcag gatactttac agctattgtg cgtgctcctc tgactggtat
     7621 catattaatt tttgaaatga caggttctgt tagccaaatg ctttcactat cagtaatttc
     7681 aattgtggca tatattgtgg ctacacttat gaagtctaaa cctatttatg aaagccttct
     7741 tgagaggtta cttgaaaaaa atggagaacc tgtacataaa gagaggggcg aaaagatact
     7801 agaccagttt tctgttatgt ttggttctcc tgttgcgaac aaggcaattc aggatataca
     7861 gtggcctgaa aattgtcttt tggtagcaat tcaaagagga ggagaagaaa ttattcctag
     7921 aggtaaaaca attcttagac caagtgatgt aattgtgact atgacagatg agagagatag
     7981 tggtgctgtg tatgataaga tggaaaattt atgtaaagaa catacatcac atatttttta
     8041 gggataatga tgaatgttta ataatgatag aatatttaat gaagatttga taattaaaaa
     8101 ttggtaattt gaaagagaat taatgagtta atataataaa atgaaaatgt gatattttag
     8161 atgtaaaaga gtttgaagaa aagagctgga tgtatttgtt aatgagatta tgtggattaa
     8221 tggtatattt atattgtgct aaaagttagt ctattgtatg agtaatggga acaaagggct
     8281 tgaaaaaaat aggtagaaga ttttttagat attcttattg ggatatttta attaatatat
     8341 tttgattgcg atattttggg aagaatagaa tttatttata aatgaaaata attaaaaggg
     8401 gttaaggtta gatgaatatc gataaggaag tattattaga taattaactt aacatctaac
     8461 agatagagtt tttatgaaaa cagtgtgtat tgaaataaaa aggtacacgc tgttttttcg
     8521 ttctgttacg caatagaatg ctatttttta gagtacgagt ataaaaccca tattcccttg
     8581 taattgtgtc tgaaaaacat cataaaatca agggattttt acacataaat gtgtaacata
     8641 ccataattaa ttgaggacgc aagtgcttat tcttttgcgc ccttgatggt attttctgat
     8701 ttttatattt atttgataaa tgaaatttgt caatcaacca caatcttaat agaagtacat
     8761 tttctgctat tgcaagaact ttctgaaaca ctgcacgcag caatccctaa agtcatgttc
     8821 tccaatgctt caagaacaat tttatcattg gcttttgata aaggttcaca tacttcaata
     8881 cttccatctg tattgagttt tgtatacata aataaattga tggggtgaat gatttgatgg
     8941 gaagttccca gagcttgatt aatattatca aaacagtttg gatgattttc tccgttgtta
     9001 taaaagaaat cgtacatctc aagtttgcaa catggatgca ataagtcatg ttcccttaca
     9061 tcatcatata aaattttaaa cataggttta tacttattag aatacattaa atttccaact
     9121 tgtaatctta atgactcatt acaatcaatt gtaacccctg gagatataaa ttcagctgaa
     9181 tcatcttgca tttctgcaaa aaaatcaacg acctgtcctc cttcaatatc cacaatttca
     9241 attttttgcc ctttagttac tttaattttt ataccactac aaggattgat tatatattcc
     9301 atatttaatg tcctccataa attccaattt atcattctgt tctatgttct cattttaaca
     9361 catactctgt ctcttttcta tttgtttctt gacgtttata acatagtcta tcatttttta
     9421 attttcataa aggtgttgta gtcttttttc aagattacag catttttttg cttaaatttg
     9481 gcattttcgt aatattactg tatttagaag taagaaaaaa tattctatat ttaaatagat
     9541 ataaaagtgt aagaaaggta aaaatctgtt ataatacatt aaaaactaaa tttagaaaaa
     9601 tttatataat tagaaaaatg atttgataaa aaataaagtt aaatactaac taagtaaatt
     9661 tgaagaagaa aaaatatgaa atacaaattt aaaaggaggt aactaatgaa aaagaagttg
     9721 gaagatatga ctttagagga attatggaac ttgtttccta tatttttgac tactcacaaa
     9781 gaatgttgga aaaattggtt taaagaagaa caatatagac taactgaaat attgccaatg
     9841 caaaaaattg ttagaataag tcatattgga agtacttctg tgagtacgat ttatgccaag
     9901 cctattgttg acatactgat tgagataatt cctgattata atatgaaaga tattaaagat
     9961 ttgattgagt ccagtggata tatttgtatg tctgagagca gtagtaggct ttcacttaat
    10021 aaagggtata cagtagatgg atttgaagaa cgagtttttc atttgcatat aaggtatgta
    10081 ggtgataatg atgagttgtt ttttagagat tacttaattg accacccaag tgttgcaaag
    10141 gagtatgaaa aacttaagtt ggatctttgg aagaagtatg agcataatcg tgatgcttat
    10201 acagatagta aactagattt tgttagggag tttactgaaa aggcaaagat gttgtattct
    10261 aatagatata attagaaata gatataatta gagatttatc ttatatatcg cattgtattt
    10321 tttaagaaag taattaatag aaaaagggat tgtttcaaaa tggagagata aatccctttt
    10381 tcattgttgg aatggtaaaa atatatttga tttcatataa aaaagagtgc ctcatcaact
    10441 aaaaagttta ttttgagaca catacatttt tactaaggta aataaaaata tcacatttga
    10501 ttaaatttta agttaatgaa tatatgtgca aatatttaat tataagttag tacaatttta
    10561 atcagtataa aacaatctaa tttatattat ataagataat ctaattttag actaaaataa
    10621 tctaatataa agaaataaag aaaattcatt ctcagtataa gagatatcca attttccatt
    10681 gtacttatta acaatttctc taatattctc aataccatat ccgtgagaat tactatcttt
    10741 tttatccgaa ataaatagtt cctgttttct attgatagga tttaccttgt tgtttgtcaa
    10801 taaatagcta aaatactcct tctcacaacg tgcctttaat accacttttc tatttgacaa
    10861 atcaggaatt ttcaaagatg cttctatagc gttatctaaa gaatttgaaa aaatagtaca
    10921 taaatctata ggttctatac ccaagtgatt gtctatatct atattaaagt gcacatcaac
    10981 accattttct tccaaacttg tatgacgaag atttaaaatt gagttaagag cttggttttt
    11041 gcaaaattgt ttgccactaa gagtacctat acctattttt aactgattaa aatacttttt
    11101 agctccagca atatcttcaa tttctaaata cgattcaatc atttgaaagt gattattcat
    11161 atcatgtcgc attttgcgta tttgaatttg ttgattttct agtaagttat agtatttttc
    11221 ttttaggtga tttgcttgtt tttctatctt catctttaca ttttcaatca atggctgtaa
    11281 aagaagtata acacctatat ttgccagaat tgctgacaag atgattagat aagtgccata
    11341 agataagttg cctaagataa tattcttatt actacccata gggattaaat tagtaggtgg
    11401 cagaataata gcaattaata ttgataaaaa tgaagatata cataccatat caataaaaat
    11461 ccatatttta tttgataagt attgctttat attaaccaat ctattcttta ggaaaatatg
    11521 tattaaaaac caaaatagta atttaataag agcagaaact atctggacta ttgaaagtat
    11581 taaaatatac tcttttgaga ttataagttc cctatacaaa gggttgttta taaaaagaaa
    11641 attaatccca actataatag ggtaaagtat catgataact gatactatgg gaattaatct
    11701 gcttttgcta catattataa gtagtacaaa atatccaaat agagtaaata aaatatttac
    11761 agggtcagaa atccatatta tcatttgact aataatagag taaccataaa tcaatatgat
    11821 tttaaaaatc caatgatttc taaaatctat aaaataggaa gtcaacttat aaagtaaaaa
    11881 ggtcatagag taaggagtgt tgtattgtaa aaaatagtgt aaataatgta gagtaaatgg
    11941 aagaaaagga gttatagagc agtaaggtta ttaagactct gcaatacaac aaaatactat
    12001 aataaaataa ataagcctct gtaatataat aaaaattagt aataaataag attctacaat
    12061 ataataaaaa tactataata aaataataag cctctgtaat ataataaaaa tactgtaata
    12121 aataagactt tgcaatataa taaaaatcta taataataaa acccaacata ataaagacat
    12181 taatttctta ctaaaaaagc cactacaatc aacagtgaaa aagcgattga aagtattgaa
    12241 aaagtaaagt gagaattaga gtcattatta cgattattaa gttttatcca taaaccatat
    12301 ataattgtac acaataataa aattgctgat attactccta taaatgtaaa aaacatcaaa
    12361 attcctcccc cttatctaat tcaagtattt ttagtctatg agaatatttt caagcattac
    12421 cataaaataa aaaaatgtac ataaaaaatc aatatagtat tattttgtaa tatctaccaa
    12481 gaataaatct aattgaaaat ctattaaacc atttctctgc tcaacattaa gaatatcaat
    12541 accactatac ttaagaaaag cattagaacg aagaaaaatc aactgaataa atgaagttat
    12601 ctgatacgca atagttctgt attcagcttc agtttttttg ttattatgat tttcatagtg
    12661 agccttaatt aaaggtagta tctcaaatgg ataaacaatt tcttcttgta ttaatatata
    12721 gggcacagaa atctttataa attgactatg ctcacctata aaatcaaaaa atgcaattag
    12781 tatttctctt aattgctgtt taggtgctaa gtttttagta tcatgtgtag ccttatattc
    12841 atccatgtga cgctttaaaa attttttaat agaagtatta attaactcct ctttagattt
    12901 aaaataataa ttaatcatag ctaaattgac atttgcttta gccacaattt ctctagctgt
    12961 aatacttgaa acatctctat gtgaagatag taactggatt gtagcattaa ttaattgttc
    13021 ctttgttgaa tctgctttca taatttttcc ccttaaaaat ttctccataa aaaaattaaa
    13081 catgtttaac acacgtttag atactatcat gaaaattttg ggatgtcaat gggttattag
    13141 tacttatata cttaagtact aatttagact tgtataagag ggatttgaat ttctgtaaga
    13201 taattttcac aatttatttc attatgttca cccctatgac cgatttgtct atttataccc
    13261 gatatttgat aatcactatt tttatctaac caataacaga acgattcata tgcaccagct
    13321 atattttcat atggaccata caccatggta catgccatca tatcaatttc ttctgtctca
    13381 cgatatataa atccagattt gttttttcca attttcttta caaccattcc aacttcaata
    13441 tctacaccat tatctttgac ttcttcatca tggtaaaaag ctatattatt gttgggttga
    13501 cgtgatactt ctatatgttc ctctttaata aatttagata acttttccca gagtatacct
    13561 tcagattggt agtctgggat tatctctcta attgatatga ttttataact tggaattttc
    13621 ttaaatacaa cattgtaatg aatttcatct ttatcacagt ttatagcttc tataaattta
    13681 tcaattttat ttattctctg ttgttcctgc tttatttcct tttgtatttc attctttttt
    13741 ctattcaatt ccttaattac aaattcatca ttccaatcat gtataatatt tgctatttca
    13801 gcaatactaa attttgaatc tctcaataat acaattcttt gtagtgttga aatctgttca
    13861 actgagtata atctatgacc tgtatattta tctatttctg ccggttttaa aataccaagt
    13921 tcatcataat aacgcaacat acgaatagaa atttgtgtta gttttgaaac ctctcctatt
    13981 ttaaacatga aaatatgacc tccttttcac ttataatcag tatatatttt gtttttatat
    14041 acttcaagag tttgtggagg tacaattatt ttccagatgt cgcaataaat tatatttaag
    14101 tagtaatcgt atcaaattat agattatctt aaattttata attcatatta aaattacaag
    14161 tctaactcaa attcaaaatc atccgatttt atctgttcaa tttcagaatt taccttttgt
    14221 ttaaatttat tagaagaaat catatataca agaaatatta gaccaaatat tatttgtaca
    14281 tattgagcta ttacacacaa tttaataggg tagtgtagaa gtaattgaac gctgaaaaaa
    14341 tagtacatca tatgaaccaa cccagccgat aaaatgcttc tactcgtatt tatatataca
    14401 aaattaatta taaagtttaa aagtacaatg tttggtataa ataaaaaagc atcaaatagg
    14461 gagtattgtg ccaaattata tggtatttga ttaggtgtaa aatacgaccc tagataccag
    14521 attccacaaa caagccctaa aataattgaa gagcctataa atccaaatct aactaataat
    14581 ttgtcaatgg cgtatcctct ccatccagct tcttgactaa gtatactcaa tataaaactt
    14641 actaatagca tataagctat ttgagaaggt ctaagtatta ctatttgtct ccaatctata
    14701 tcagaagttt ttacattaaa gtagtttccg attgttagag aagtaataaa ggttaaagca
    14761 aaaaataata ttgttaataa tggccatttt attcccattt ctttaaagct taggtatcta
    14821 taaatgaagt cttgttttgc actttgtgga tagattgtag aaataaaaaa tagacctaca
    14881 atagctggtg atgtatacgc aagataaaaa atgatttctc caagtatcgt atttgtaatt
    14941 ccgagtaatg caggtgtaag actgaatatc cagttcaata ctagagtaag tgtaaagaaa
    15001 tagattaaat ttttgtttgt attaaatggg gtgttatata gttgcatttt ttcactatcc
    15061 tttcgtttta taatggaatt tgaattttta ttgattgttt atttatttct atatgtattg
    15121 agttatcgtt taatgttagt tattgattat aataatatcc tattcttatt ttgattaatt
    15181 gtttttacac taaatataat caattaatat ttaatattga acatattata ttatttttaa
    15241 ttattaaata ggtcaataaa tttgcaatta gtgatattaa taaagtactt tacattttta
    15301 ttaaatattt agcttttctt taatattttt tatataacaa cgatttataa taactttttc
    15361 gttgtttctt aaagtagctt gcatacgatt atgtgatatt acttttatac tttttatgta
    15421 gtccatattt aaaatcatgg atttggatat tcgtgagaag gatgtattag ctaataattt
    15481 tgataattta tatattttta aatcaatttc aaatacatca tcttcataat aagcaaatgt
    15541 tttatttcca actgtctcaa agtataaaat atcacagaca ttgagcttat aaatctctcc
    15601 tgatttttta ccctttatat caagtaatgg tgtactcaat aatgaaatta ttttttcaat
    15661 gttattatct agagtagaac attttatggt tatttcaata tcatcgcaat taatgccttg
    15721 ttcgacatgt attttcatta atcttcacct cattttatta ctgtcattag aatagcatta
    15781 tatcttattg agtccaacta gatgcgttct aaatttcaaa ttaagtatag tgaaattcaa
    15841 aaatgaaacg gtgaaattca aatttgaggt ggtaaaattc aaaaaaatac tatggatatt
    15901 tgggtaaatt atccaaatat cctagtattt ttcatagaat atatctaact attttacaaa
    15961 tagacttatt ttatgactta catatattgt caaattactt cttaaatagc aaaatatttt
    16021 tggatagtgt atcaatactg tttgataaag tatttaattt accctcaatt ctaaccaaca
    16081 aatacatgga cagagctata ggaaaaccaa cattggttat taacagctgt aaactatcat
    16141 ccataaaatt agccccctat tcttataact aaatcataag gagtggtatt tgtttccaca
    16201 actttggctt caacaacaga agctaggtca aatcctccaa ctgaaaaaat atttttagat
    16261 actatcaaat ccatgacaga ttttatattt tcttcagtta aatcatcctt tggattttct
    16321 atagaaaaag aaacttgttt atcctttaca tttttaaaac tcatgactaa ttttttctta
    16381 atttccatat aattacctcc gatataataa tttatatttt aattgtttga ttgttaatat
    16441 taattgttta tactagttat tgctgatata gaaaatgttt aatttatttc aattaattag
    16501 attgaagtag ggtagcattt aaaatagcta acatgtttaa gttgaaatac gtttaatata
    16561 ttaattttta aagtatcaat atattaaagt tataactcaa attgaaatta taacctgcca
    16621 aatctacagc gtattaagtg cgttacataa ctaaatcttt tatataaaga gttaattttt
    16681 taatttgcaa atcagattat gtttaaaaga cactatttag atagtgatgt gctatctaat
    16741 tttaaaatat ctacaatagg gttctcttga agacttgcta ttgcttctgc aacagcataa
    16801 acatcctcat ttaatgcctc tgcttttacg tttgcaaatg atttactttt aataactgcc
    16861 ttacccttat cgtcaaaacc agcatccaat tttagtttta tactagataa attttttgtt
    16921 gaaacaactt ccataaaatt acctcctaaa aatttaattt caaagatttg tcgactttct
    16981 ttgttagcta taatactatc atctaagata atatcggagt taaacagtaa tttctaaaga
    17041 ttttttgtgt aaatttttat aggaaaaatt ttccttatga acaataataa gtttacaaat
    17101 tattcatgaa gatatgtttt tagcgttttg aaatagtatt tgtatatatt cctaatttag
    17161 ttgggatagt tttgtataga attttatatg tatagagtta agtgttagag gttaaagttt
    17221 gtataaaatt aaatgttaaa gtctatgtta aaaattttat taaatttaat ctgtaaataa
    17281 aaaagttaaa agtccaatat taacatttta cttttaaacc attaaaatct ttattaaagc
    17341 taacaaagtt ataagttata agaaatttta ttaaagttaa tacagaaatt aattttaaag
    17401 ctaagaaatt ttttgttagg tccaataaaa ctaataaata tagtttagtc aataatgtat
    17461 taaacaaaaa ctttgttaag tctataaaaa tatattaaag gaggtgtaat ttatgaagat
    17521 aaaagtggaa gatataccag ttcaatttca tgcaatggta gaaataatcg gaattgataa
    17581 gttcatagag gttaccaagt tgtatggagg aacaaatact tatataccta cgtataatgg
    17641 actttttaga tatgctagaa atagggaaat agtaaaacaa tttaatggag tcaactacaa
    17701 tgaattggct attagatata atatgtgtgt aagcaatatt aagcgaatac tcaatgaaaa
    17761 tagtgtttaa gtataatgaa aatagtttta ttaaatgtaa gtgtaatgat aaagaagatg
    17821 ttttataaag tttttttaga caaattaact aaatttacta cttattaatt taaatacatt
    17881 gtatattctg taaaaaaatt tgttagatac tgaagataca ttgagaatac aaagaaaata
    17941 gtcgaaaata tttgttggct aaaaaataga taaaatgata caattgcttg tataaaaggg
    18001 aaaaataaat aaataaacta tataaataaa gaaatatcaa ttaatatgac ataatatatt
    18061 tataatatta ggaatataaa tagatatttt aaggaattag ttgtgaaatt agaaaatatt
    18121 aaaaaaaata tatatttata tttaaaaaaa tttgttattt atataaaaat acttatctag
    18181 ttactagcaa ttattagtag aaatggggga aatagagatg aataatggat tttacaaatt
    18241 aaattcagca gtattgaact ttgatattaa gagtgatgtt aacaagataa gatttaatca
    18301 ttatataatg agaaaagaaa acatacaaag acttcaagga actctaccaa gaggacaatt
    18361 ttatatgaca gtgagaagag ctgctacaga tttacaactt tctatttcta ctataagtag
    18421 gcttgtaaga gagtttttgg atttggggat aataagatta gtgtctaagg gtgtaaaagg
    18481 taatcgttct gtatatagtt atgtaagtat agagtttaat ggaagtttat ttgatgatag
    18541 caaacatatg gaacttgatt gtgtatgtaa tgatgaattt gttgataata gtgacataga
    18601 gcttgattgc aatagtaaag ataattcttt taatggagat ataaatgtag aaactgagta
    18661 ttgtagtaat gagtatttgt ttaataatga tgtagagcat aattatgaca atttctataa
    18721 caaagatact ataaagaata aatccatttt taatattagc actatcaaaa aatatatcaa
    18781 tgaatctttt gatacaaata aatcagaaaa ttctaactta caacaagaat caataaattt
    18841 taactttaat gatacatgta atgcaataga taaaagaacg aataatagta taaaaagtaa
    18901 tcaaaataaa aaggctatga aattgagtga catcaatgtt ttaagtgata aagatattac
    18961 aaataaaaag aattacttta atcatactca tggcatacaa aaaggcacta aatctgtaac
    19021 aaagaaaaaa gaatccttaa ataaatttaa taaaaaaaat atacagcaaa gcattataaa
    19081 tatgctaaat aaaaaatcag gtaagaattt taaaatcgat tctccaataa gcataaaact
    19141 tatcaatgaa aggctaaagg agggctatgt cttagaagat ttctacaaag ttattgaggt
    19201 aaaagtggct aagtggaaaa acaccataat ggaaatgtat ataagaccag aaaccttgtt
    19261 tagctataag tttgagtcct atgtaaatga aaacatatct atgaaaagtc aaagtaatat
    19321 tcacccgtgt aaagaaggca atagtaatga tagcagtaat tatatacatt ctaattatac
    19381 aacgtatgat gacagtgtgc gcgagagaaa aaaatatgaa aatgtaagat actggaatcc
    19441 tatatgtgaa atttaattag tctaagaatg tatttatgat aaataagatg ttaatagcga
    19501 atagtgagct actgcaaatg atatatcaat aactagtagt gaattatatt gaatgatata
    19561 tcaataattg gtagtaagtt atatcaaata agatattact atcgagtagt gaattatatt
    19621 gaacaatata tcaataattg gtagtaagtt atatcaaata agatattact attgagtagt
    19681 gaattatatt gaacaatata tcaataattg gtagtaaagt atatcaaata agatattgct
    19741 attatgtagt aaattatata aaacaatgta tcagaataaa gagtatatta ataatttgta
    19801 gtatatcatg acgaataata tagtcataac aaatagtgtg tcataacaaa taatgtattt
    19861 ataattgata atatatttaa aaatcaaaat ataaaaactt atgaggaaag tgagattaat
    19921 ttatatgggt aaatcaaaag atgttgaaat agagaagtct attttaggca caattctttt
    19981 agacaataaa ttaagctata agctagatga attaaatgaa aacatgttta tgaatgatat
    20041 atgtcttgag atatttaaaa ttatgaaaga acttaaaaaa gaaaacatag tgattgatgt
    20101 ggccactgtg aaatcaaaga tagataaaaa atctctagca ataaaaacga gtgatgtgac
    20161 taatataatt acttggggtc agaattttgg gcttgatggt catattaaaa ttttaaaaga
    20221 aaatttagct agaagaagca taaatcaaac ctgccaaaac cttttacaca gcctaaatct
    20281 tggagaaaat atcgatactt gtatttacaa atttgaaagt aatataaagg agattttgga
    20341 caaggatact tatgaaaatg atgatgtaaa tagtatagca gggaaggtgc ttgatttttt
    20401 agaaaacaaa aaagatattg gatttaaatt tggtataaaa ttacttgata ccactatagg
    20461 aggtcttttt aaaggagagt taactacaat agcagctaaa tcaggggttg gtaagactgc
    20521 tttggcactt caaataatgt taaattcatt taagcaagga aaaaagactt tatttataag
    20581 tagagaaatg accagtgagc aagtatttat gagaaatata tgcagagtaa ctggtgtaag
    20641 tacaaggaat atgaaatcta aagaaataga tgaaaatgac tggaaactta ttgtaaatgc
    20701 gataggtgat ttaagcgaaa ataacttaat ttatatcaat gataaggtag atacaattag
    20761 tgcaattaga aagaggataa ggcaggtaaa accagattta ttgatagtgg attatgtgca
    20821 actccttaca tctcagaaaa gcatggataa aagagaaagg gaggtagcta ctttttcgag
    20881 ggaactcaaa aatatgactt tagattttaa tatacctgta attcaattaa gtcagttaaa
    20941 tgatgaaatg aaagattcaa gaccttatgg agatagacct atgagggata gtaaagccat
    21001 ctaccacgat agcaacaatg tggtttatat acatcaatta aaggggagtg attatgaaga
    21061 agcagtgaga gatattggag aaagtgagga ggcagttaga gcatcagaat acaggggaat
    21121 taagatggtt gatttaatag ttgcgaagtg tagagatgga cagactaggc ataagcattt
    21181 ttgttacttt ggggataagt tacattttca agagctaaat tattaggtca ataaagtagt
    21241 aataacaagc ttattaaaag tcgggaaata gcaaatagat tataaaatat gaggtgaaaa
    21301 tatgttggaa ttaacaaaaa ttatagaatt acttgaagaa cacaagatag aagtaagtat
    21361 tccaaaggag ttacataagt atagtttatt ggaatacctt gaattgtgtc aacaaagtgg
    21421 gggaacatat ttttatatta agacactgga aggggcttta aaagaggcta gaaatgagct
    21481 tattattaaa ttgtttaatg ggaagaatta tatggaatta gcgaggatgt ttgaaatgag
    21541 tgttattaat gtcaggcata ttgttagaaa aaaatagata tttttggaga atacaagtgt
    21601 gatatacttc tgaaatagaa gttattataa ttgaaataaa attttggtta atagattaaa
    21661 gttgtgtata agtttaagat tatagaggag tataagtgtg attaacagca tgattttgtg
    21721 aataaaattg aggatatata tgagctaaat gtgtgattaa taaggtaagg ttgtgtataa
    21781 gattatgagt atgtaaaagg atagtctata attaatagtt cagagttgtg tgtttggtta
    21841 agattatata agaatttaat agattaaact atactaataa ggtaaaatcg tgtgtttagt
    21901 taaagcttat tataaaatct tgatacatga ttaatgatgt aatatgtgaa taaagttaag
    21961 attataatag gtttaaattg tgactaatag aataaaattg tgaataaagt taagattgta
    22021 ataggtttaa attgtgacta atagagtaag agtgtaaaca gagaaaaact tcaatatgag
    22081 cttaacttgt gattaataga gtagggtgta acaaaagaaa aatttcaata tgagcttaac
    22141 ttgtgattaa tagagtaggg tgtaacaaaa gaaaaatttc aatatgggct taacttgtga
    22201 ttaatagagt aaggtgtaac taaagaaaaa cttcaatatg agcttaatct gtgattaata
    22261 gagtaaggtg taaatagaaa taaacttcaa tatgagctta acttgtgaat aatagaataa
    22321 gattgtgaat aaagttatag ttttagatgg gtattaacct gtgactaata gaatatgatt
    22381 aggtgtaaaa ttatagagtt gtataagaaa atattataga tatattaaat attagataat
    22441 aaatatttat atagatacac aaaagaaaag gcgatatgaa gttaaactta atgacttcat
    22501 atcgtttttt atttgaaatt cctctgtatt tagagtgtga tttttaatat tgaggtttta
    22561 tgtgattaag tcacagataa aaagtaagta tcctgatata attcttatag attaataata
    22621 ttggggaggt tattatgtct aataaaaaaa agaagtatgc aaatatttta gcaaatgagt
    22681 gcgttgcttg tggtagctgt ataaaagcat gtccaagaag tgctatctca gttccatgtg
    22741 gcattagtgc aaaaattaat agagatttat gtgttggatg tgggatttgt gaaaagatat
    22801 gcccagcatc tgtaattgag attataacaa tattaaaaga ggaagaaggt aagtgtcatg
    22861 aataataaaa aacattggta tgactattta tggatttttt cttcagtata tttgatattg
    22921 ggatttgtaa atattatttt cgcttggatt ggactaattt gtttctttgt tccactagct
    22981 atttctattg ttaagggaaa taaagcttat tgtaataagt attgtggaag agggcaactg
    23041 tttaatttgc ttggaaataa attgaagctg tcaagaaata gagatattcc taaatttatt
    23101 agaagtaagt ggtttagata tgggtttttg acatttttta tggtaatgtt tgccaatatg
    23161 cttttttcaa cttatttagt atttgaagga agtagaaatt ttaaagaagt agtgactttg
    23221 ttgtggacta taaaaatgcc ttggcaatgg gcgtatcatg gaactttagt ttctccatgg
    23281 gtggtacagt ttgcatttgg tttttatagt gttatgctca catcaactgt tcttggtttg
    23341 attactatga tgttgtttaa gcctcgttca tggtgtgttt attgccctat gggtactatg
    23401 actcagatga tatgtaaggc aaagagtaag tctgtataga aagaatttat gtgatattta
    23461 agagtttgtt caagtagaga tgagtagtag gtttgaatat atgacaaata tatgagtata
    23521 ggggcataga tttagtttgt gtaaggtaaa ctgatttatg cttctttttt atgtcttaga
    23581 ttattggcta agtggaaata attaatttag atattaagaa ttattcagtt atttgaagaa
    23641 aatataataa ttaacattat atgaatggat attcattaca tataagccag ttaatagcaa
    23701 gatttattta atatgaagta ggtcaagtat ttaaactaaa taagatcatg acaattaata
    23761 taagtataga tataaaaaga ttaaaagtta taacttataa aaggtattct atataaatag
    23821 tatgggaaaa atagtcaaat taacttatta gaaacaaaaa atatacataa aaaataaatg
    23881 taaatatcaa ataaggtact atatcaaaat agatataagt atctttttta ttattgaaat
    23941 tatgaaaata tatttgattt tacacaaaaa agagtgcctc atgaactaaa aagttcattt
    24001 tgagacacac ttttacagtg tcaaagaacg aagtttatcc ttatccaata cttttatacc
    24061 accacgagat aaagacacaa taccttctct agcaaaatat ttcaacattc tcgatacaac
    24121 ttctctggca ctacccatat acttagcaat ttgttcatga gtcatattta tagtgctact
    24181 accattttta gctatctcat caattaaaaa agatgccaaa cgcttatcaa aactcataaa
    24241 aagaatttgt tgcatagccc acataacatc agaaaaacgt tcagtagcta atttatatga
    24301 aaataactct gcatgaatat tttctgtaga taattttgca aaaacagagg aactaatctg
    24361 tataatatcg cagtccgttt cagcatctac atagacatca aaagttattg tttttagaat
    24421 acaggaagct gataaaatac atacatctcc atcatcaagt cggaacagtg taacctctcg
    24481 accttcatct gaaagtatgt atgtgcgtat tgttccagac tttataatca aaataccaat
    24541 acagtcacta tcaccacaat gtacgggatt cccttttttg taatgcgagg tgtttgctga
    24601 agaaattaat aattcttttt gtaagtcagt aagtttatcc caaaaaggca agctatgtgt
    24661 aagtatatca atttcatttt gtgaaatcat accatatctc ctttcttaaa ttgttataat
    24721 cccatgatac aagtgaatag ataaattgac aagtagtttg ttaagaggat tatttagtca
    24781 gatagtaata gtatgattta tgtagaaaaa atatgataat atatattctt gctattaatg
    24841 aaaaagtgat atatttttga tgatagtaga tgtgtacaac tattgcatac agtttatttt
    24901 taaaagatta agttccttat gtaaccttat agacataaaa cctgcaatta tcgtagctat
    24961 caaatcagcg attggttgtg catataagat accatttatc ccataaaata atggtaggta
    25021 atcccataga taacaatgct tttgggattg gggcagaccc taataattca attcttttgt
    25081 tactttcttt catattcaac acttcccttc tattgacatt aagtctaaat tataatacta
    25141 taaattatag tgaatatgga aaatagtact ataatttata gtatttgtca atagtaagaa
    25201 aactaaagga gatgattttt atggctacaa tagacttaat tgtattggga atagtaaagc
    25261 aacaacccaa gagtgcttat gatattcaaa aggaagtgga atacaggaat atatcacgtt
    25321 gggttaaaat aagtacacca tcaatttata aaaaagtaat tcaattagaa caaaagggat
    25381 atattgaaag taaaactgtg aagaatggaa aaatgccaga aaaagcagtt tattcattaa
    25441 ctgaattagg tgagacacat ttcttagact taatgtttga tacatctagt aaaccaataa
    25501 atattctttt agattttaat gctgttatag taaatttaaa tagccttaca ccagaaaaac
    25561 agaaattatg tctcaataat attgaagaga atgttcaaga gttaaagaaa actattgagg
    25621 aaaatataag tataaagaca gaagtaccag agacagcaaa agcagtgttg gagcaacagt
    25681 tggtactagc acaatcattg gaaacatgga taaattcttt aaaagataat atggggaatt
    25741 agaattagag aagctaactt aataatcatt aaacaaaaac cagcatattt aataatgaga
    25801 tattagaaaa aatgaaacaa atgatataaa ctgaaaagta tatttaaaat aaagctcact
    25861 taattgaggg tgaatgttaa actttctaag tgtaaggagg cattattcag gaatctactc
    25921 gactactgtt attgttaatg gtgtagaatc aggtaacctt aattctggat taggcatatg
    25981 atttgatttt gaattaggtg tataattttg ttaataagta gaaaaattgg aatctgtagt
    26041 cgtggttgta aatttcactt tatcattgat taacatagct gttgatagaa tatttcaaaa
    26101 attagaattt ggagagtgag cactatggaa gaaaaataca tcttatctga ccgagggaaa
    26161 gtatattatt ggataaaaga aagtaatagt gtgtttgcaa agaacttaat ttttttgcca
    26221 ggactaacag caaatcatca tctttttgat ttccaaatac agtacttttc aaaaaatcat
    26281 aatgtattgg tatgggacgc tcctgctcat ggaaaatcaa gaccttactt agatttctca
    26341 tattctaact tggtagaaga attgaaagta attttagata aacaaaatat gaaaagggtt
    26401 gtacttatag ggcaatcggc agggggattt gtggcacagt cctttattgt aaaatatcca
    26461 aatatggtag aagggataat gatgattgga acttgtccat atggaattga ctattatagt
    26521 aagttagata ttttctggtt aaaacagact gaatggatgt taaagttgtt cccagataga
    26581 ttgttgcgaa acataatatc taagatgtgt ggagctacgt ctgaaggcag aaggagtatg
    26641 ctgaaaatgt tagaaggata cgaaaaaaaa gaactgtgtc atctcatgta tctgggattt
    26701 gctgggctta taccagaaat tcaagactta aatatacatt gtccagtttg tttagtagtt
    26761 ggagataaag acaagactgg taaagtaaga aaatataatg agcagtggca caataagact
    26821 ggatatccat tgcacattat aaaaaatgct tcacataatg taaatgtcga taaacctaat
    26881 gaactaaatc agattatgga tatatttatt aagcaattat aatatataaa aattacatac
    26941 ccattaggta aattatgtag tatatgtgtt tatagatggt tatagaaata aatatgtaat
    27001 aaactactta acacttaaaa agtagacttg tctagtgcat aatacaaagc atgatatata
    27061 tttttaagcg aaatacatta aaagaagaac tagtggagat aaaacagata ttagatatta
    27121 taaatgatta acttaaaagt actataagtg tagagaaaga tgactcatac gttattaagg
    27181 gattgtaaat gattagttta aaagtactat cgtataggat tctgcatatt tagaccctag
    27241 taaagatagt taaagtagtt taaaaactaa aaaattatat aaaggaatta ggtataagaa
    27301 aatgattgag agtataccag caaaacaaat tttacaaaaa gtgaaatttg acaatacaag
    27361 atggtttgga attgactata atatgaacct ctatcgtggt tgttctcatg gatgtatata
    27421 ttgtgatagc cgtagcacaa tatacaacat agagaatttt gacaaagtta gatataaaga
    27481 aaatgtgata gaaattttaa gtaaagaatt gcgttcaaaa agaaaaaagg gggtagtagg
    27541 cattggagct atgtctgaca catataatcc ttttgaaaag caactttgta ttacaaagaa
    27601 agcactagat ttaatttcgg aaaatcattt tggagtgtct attgatacta aaagtagttt
    27661 ggtggttaga gatataccga ttttgcagaa gattaaaaaa aataactctg ctattgtaaa
    27721 gttgactata accactgcaa atgatgaatt atcaaagaaa atagaacctt atgtaaatcc
    27781 aagttctgta cgatttgagg cagtgaaaga acttaatgat tctggaattt tttgtggcat
    27841 attattgact cctatgcttc catttttaac tgataataaa gatgaaatac gagcaattgt
    27901 agaaaaagca cacaaggcta atgcaaaatt tatttattgc atgtatggtg taacaatgcg
    27961 tagtggtcag agagagtttt tttatgagca tttaagagat atatcaccaa aattggtact
    28021 taaatatcag aaaacatatg gtttaaacta tgtatgtact gtacaaaata aagatggttg
    28081 tgagaagttg ttaagagaag aatgtgcacg ttatggtatt ttgacggata tgaaagagat
    28141 tataaaagcg tacaagaggt cggagtcata tactcaaata aaattttttt aagataagct
    28201 ttggataaga tataatagtg atgattgatg tgttgatact ctaggtaatt actagagctg
    28261 acattataat tgaatattag tattgatatt ctaggtaatt gttagtgatg atattataga
    28321 tgaatattaa tattgatact ctaggtaatt gctagagcta atattataga
//
LOCUS       DBGJFK010000047        28173 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.047, whole genome shotgun sequence.
ACCESSION   DBGJFK010000047 DBGJFK010000000
VERSION     DBGJFK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.047"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(181..402)
                     /locus_tag="ACOIAP_002369"
     CDS             complement(181..402)
                     /locus_tag="ACOIAP_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639251.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(805..2082)
                     /locus_tag="ACOIAP_002370"
     CDS             complement(805..2082)
                     /locus_tag="ACOIAP_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2639252.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEVKADQERITKAINNIINNAIKYSPEESEII
                     IRLYDKNKRISKKNSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVIFTVEFKN"
     gene            complement(2066..2734)
                     /locus_tag="ACOIAP_002371"
     CDS             complement(2066..2734)
                     /locus_tag="ACOIAP_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639253.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            complement(2894..5395)
                     /locus_tag="ACOIAP_002372"
     CDS             complement(2894..5395)
                     /locus_tag="ACOIAP_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGZ2639254.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYNPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMKNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKALFSLSPNMDSLVAIGTLAAFLYSLYTTIQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAVVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINNENILLGNRKLMNDNNIKLGDLEEKSNLLAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNVKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            complement(5686..5877)
                     /locus_tag="ACOIAP_002373"
     CDS             complement(5686..5877)
                     /locus_tag="ACOIAP_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HGZ2639255.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(6025..6267)
                     /locus_tag="ACOIAP_002374"
     CDS             complement(6025..6267)
                     /locus_tag="ACOIAP_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639256.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            6479..8302
                     /gene="typA"
                     /locus_tag="ACOIAP_002375"
     CDS             6479..8302
                     /gene="typA"
                     /locus_tag="ACOIAP_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGZ2639257.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEELSPLFKTIVNHVEAYPDYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(8392..9300)
                     /gene="trxB"
                     /locus_tag="ACOIAP_002376"
     CDS             complement(8392..9300)
                     /gene="trxB"
                     /locus_tag="ACOIAP_002376"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGZ2639258.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKIKIVKTSSAEHKAKA
                     VILANGVERRKLGCVGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARKNIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    10086..10316
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10424..11905
                     /gene="thrC"
                     /locus_tag="ACOIAP_002377"
     CDS             10424..11905
                     /gene="thrC"
                     /locus_tag="ACOIAP_002377"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGZ2639259.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSKFPNVKNELID
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVDNGEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLNDKGVYKISEDMEKNLASFHGEYSNEEEVKNTINSVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            11915..12808
                     /gene="thrB"
                     /locus_tag="ACOIAP_002378"
     CDS             11915..12808
                     /gene="thrB"
                     /locus_tag="ACOIAP_002378"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGZ2639260.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIENGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPTGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLVSALINKNFELLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIRENDDSFVDNMRNYLQNL
                     KSDWEIKELYCDSNGAVLNIL"
     gene            12935..13993
                     /locus_tag="ACOIAP_002379"
     CDS             12935..13993
                     /locus_tag="ACOIAP_002379"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HGZ2639261.1"
                     /translation="MIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVIS
                     GVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEAV
                     KAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIVV
                     EGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGKKIPVVAAGGITSSS
                     DVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAIR
                     NKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAYK
                     IDKLSTVEDVINELISEL"
     gene            complement(14147..14659)
                     /locus_tag="ACOIAP_002380"
     CDS             complement(14147..14659)
                     /locus_tag="ACOIAP_002380"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGZ2639262.1"
                     /translation="MSDFKEILAEEIKSNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QVGFNIEHLNNTPYFKEAKMALICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKEA"
     gene            15181..16116
                     /locus_tag="ACOIAP_002381"
     CDS             15181..16116
                     /locus_tag="ACOIAP_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGZ2639263.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSDDPNGFWIILLISAIICIVITFFMSRNKLL"
     gene            complement(16208..18079)
                     /locus_tag="ACOIAP_002382"
     CDS             complement(16208..18079)
                     /locus_tag="ACOIAP_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGZ2639264.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKIESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFIRCEKWLKSAADNNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNVEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     AKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEDFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDN"
     gene            18272..19198
                     /locus_tag="ACOIAP_002383"
     CDS             18272..19198
                     /locus_tag="ACOIAP_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HGZ2639265.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTNKSFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLLLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            19337..19483
                     /locus_tag="ACOIAP_002384"
     CDS             19337..19483
                     /locus_tag="ACOIAP_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639266.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(19588..20112)
                     /locus_tag="ACOIAP_002385"
     CDS             complement(19588..20112)
                     /locus_tag="ACOIAP_002385"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639267.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     ESMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLARVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(20165..20389)
                     /locus_tag="ACOIAP_002386"
     CDS             complement(20165..20389)
                     /locus_tag="ACOIAP_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639268.1"
                     /translation="MIIKLTKDDFNFRFKQYEGMFFHAEIIESMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQIEAYIDLKSIK"
     gene            20586..21710
                     /locus_tag="ACOIAP_002387"
     CDS             20586..21710
                     /locus_tag="ACOIAP_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HGZ2639269.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     VLSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIFLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLENNTSIQSKQHSVKELTKLYKFLIIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESKFWQKYEGKID
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(22184..23008)
                     /locus_tag="ACOIAP_002388"
     CDS             complement(22184..23008)
                     /locus_tag="ACOIAP_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5780 domain-containing protein"
                     /protein_id="HGZ2639270.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTSVYLASTVS
                     TITKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(23356..24411)
                     /gene="ispG"
                     /locus_tag="ACOIAP_002389"
                     /gene_synonym="gcpE"
     CDS             complement(23356..24411)
                     /gene="ispG"
                     /locus_tag="ACOIAP_002389"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HGZ2639271.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(24594..25598)
                     /gene="rseP"
                     /locus_tag="ACOIAP_002390"
     CDS             complement(24594..25598)
                     /gene="rseP"
                     /locus_tag="ACOIAP_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGZ2639272.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFWGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(25611..26765)
                     /locus_tag="ACOIAP_002391"
     CDS             complement(25611..26765)
                     /locus_tag="ACOIAP_002391"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HGZ2639273.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELVNITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYADSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(26929..27132)
                     /locus_tag="ACOIAP_002392"
     CDS             complement(26929..27132)
                     /locus_tag="ACOIAP_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639274.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            complement(27822..>28173)
                     /gene="cas2"
                     /locus_tag="ACOIAP_002393"
     CDS             complement(27822..>28173)
                     /gene="cas2"
                     /locus_tag="ACOIAP_002393"
                     /inference="COORDINATES: protein motif:HMM:TIGR01573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HGZ2639275.1"
                     /translation="LFYYNLPRFCLFFSLNSILHMKKKNNLNYNYVFVVYDVGEKRVS
                     KVFKVCKKYLSHFQKSVFRGEITPSKIMSLKRDLENIIDKDNDFVCIIKLMNSNTFEE
                     EILGNNSNCENMIL"
BASE COUNT         9499 a         4491 c         3259 g        10924 t
ORIGIN      
        1 ttaaaattta gttctataat atcgatttta tccttatgtc tattcataaa actaatttga
       61 aatagacttt ctaaatctaa tacagttatt tttagaaagt ctatttcctt aaataaacta
      121 tttaatatta ctagctactt tttatatgaa cacaataatt tgttattcat aaataaaaac
      181 ttatttcatt tcattcttca tttgcttttc taattcttta gaaaatttct tttgttcata
      241 tctttccatc atctcatctt ttttcatttc taagtttacc atagcacctt gtgcatcatc
      301 tttcaaatct tcagctgtat ttttcataac ataagctgtc tttttaactc cttcttttaa
      361 atcttctttc atatttttca tatctctttt taatctgtcc atcaaaacta cctcctcttt
      421 aaatataata ctttctatat ttatttttcc caaagtatat atatttattt gtaatatcaa
      481 ttataatttt taagccctta aatatagttt aagactatct aaatctatac atttcaataa
      541 attagaaatt ttttatttca aaataaaaat aacactaaac atagattata tgtctggtgt
      601 tattttttaa attcatagta acttaattgt tgggttacta taatgatgac ttctatggag
      661 gatgtaagga aatctcatca ttatagttgg tgtattttat ggtttaaagc ttctttatat
      721 ttatataata cagtttcagt atgaattttt tgtgatttta aaatgaacta ttattgaaag
      781 ttatatattc tttataataa gtaattaatt tttaaattcg accgtgaata ttacagagtt
      841 ttctttgttt tttatgctat aatcaaaccc atgactttta aaaatttggc tgactatata
      901 aagtcccagt ccacttcctc cagtttttct tgaacgagat ttttctattc tataaaatgg
      961 attaaatatc tcttctaaat aacgtttctc gatagttaca ccagtatttt caatctctaa
     1021 aaccactctt tgattagagt tctttttact tattcgttta tttttatcat agagtctaat
     1081 tataatctct gattcttcag gagaatattt tatggcatta tttattatgt tattgattgc
     1141 cttagttatt ctctcttggt ctgccttaac ttctaaattt tcttctattt ttaaaatagt
     1201 tttcatatgt ttttcttcta ttaaaaatac ttgtcttttt acaagtctat ttaataattc
     1261 acttatattt attgatacca atttcaaatc tttttcaagt atttctgatt ttgaaacctc
     1321 tatcatttca tttactaaat cttttaattc ttgggtacat tcatacgatt tttttagata
     1381 agtatcccta tccttatact tacctacact gtaaatcata ccttcaattt gaccacttat
     1441 tatggttatt ggagttttta gttcatgtga tattgtagcg acaaaatcct tccttctata
     1501 ttcctgctct ctctcactct ctattatatt tataagcggt tttgttatta caattgaata
     1561 tatatatgcc ccaataatcg ctatcaatat tgctattgat ataatgtacg gcatcagttt
     1621 tcttataact tcgtttgctt cgtcaattgg ttgtaatggc ataacgagct ctaaagtata
     1681 tggcccatct tttgcatctt tagtatatat aggtatagaa gtcctatact catcctcaag
     1741 actattaatc atgtacttac tatatcttaa aataactact tcattcttac catatacaat
     1801 tttcccttgg ttatctttta ataaaatagc caaattttgg tctttagcca tataataaag
     1861 tctttcttcc aaagtatatg tatcgaaatg aattgaacta tccactaaag actttaaact
     1921 ttcttgaaga gactcaattt tatactcatg ataatatgat ggcaataaaa aatataaaat
     1981 tagatatatt attaaagcta atgctattaa taatgatgtc gttattgaaa ataacttata
     2041 ctttatactt aacttttccc acttatcaaa tatccttctc aagtgtatat cctattcctt
     2101 ttacagtttt aatatatggt aatgatattt tttttcttat attttttata tgtgcatcaa
     2161 caatcctagt atctccataa tagtcataac cccatatact atccaaaaga ccttctctag
     2221 ttataacctg tggatacttt tctatcaaag cttttaatat attaaactct tttagtgtaa
     2281 gttctatagg ttctccatct atttctgcaa tatatgtgtt taaatctaat tttaattttt
     2341 caaaaactat aaatttgtca tttatagtct tgttacttcg ccttaaaatt gcctctactc
     2401 tttttataag aagattaaat gaaaatggct ttgttatata gtcatcgcat tctaagtcaa
     2461 accctttaag ttggtctcct tcatcattta aagcagttaa aaatataatt ggaacgcttg
     2521 atgacttcct tatcatttta catactccat aaccatctaa atttggcatc attatatcta
     2581 atattactaa atcataactt ccttgcttaa acttttgtat accttccaac ccatcatttg
     2641 ctgtatccac ttgataacct tctgcactta aaaattctga tattaattct tgtatatttg
     2701 aatcatcttc aattacaagt attgacgaat tcattctatc aatcctttct attttattta
     2761 aaatttcata tattacttat attttatctt attgttgtga attttacatg aaaaaagagc
     2821 tatcttaatt tgtaaattaa tccttttaat ttaaagatag ctcttttgga tacattcttt
     2881 ttaacttgtt aatctagtct ctcttgtatg ccttgaagtt tttaagtcta agtgcatttg
     2941 atacgactga aactgaactt aagctcatgg ctgctgctgc aatcattgga tttaacagag
     3001 gtcctccaaa tacatacaat attcctgctg ctacaggtat accaatcgta ttatatccaa
     3061 atgcccaaaa taggttttgt tttatatttt ttatagtttc atgactaagt ttaattgctg
     3121 ttggaacatc aattaaatca ctcttcataa gtactatatc cgcagactca atagctacat
     3181 ccgttccact tcctattgct atccctatgt ccgcttttgc aagggctggg gcatcattta
     3241 ttccatctcc taccattgca acaaacttgc cttgattttg tagtttttca acttcttttg
     3301 acttatcttc tggtaaaacc tctgctaaaa ccatatctat acctacttga tttgctatag
     3361 catttgcagt tttcacatta tctccagtta ccattgcaac ttttattccc atatcatgaa
     3421 gtatttctat tgctttttta ctactttctt taactacatc tgcaactgct attatacctg
     3481 ataaatttcc atctacagct atatacatag gtgttttacc ttgacttgcc aataaatttg
     3541 atttttcttc taagtcccca agctttatat tattgtcatt cataagcttt ctatttccaa
     3601 gtaatatatt ttcattatta atagtaactt gtatacctgc acctggtata gctttaaaat
     3661 tgtcaacttt ttcaaatttt atattcttct cttctccata cttaactatt gcttctccaa
     3721 gaggatgttc tgaacctttt tctgcacttg aagcaatctt gataagatac tcttctttta
     3781 cattattatt taatactata tctgttactt ttggctttcc ttctgttata gtacctgttt
     3841 tatcaaatat tactgtattt actttatgtg cagattctag tgcctctcca ccttttatca
     3901 agattccatt ttctgctccc tttccagttc caaccattat agcagttggc gttgctaatc
     3961 ctaatgcaca aggacaagca attacaagta ctgatataaa tatagtaagt acaaatacta
     4021 tatcttttcc tcctattaaa aaccacaata atgatgcaac tacagctatt gcaattacta
     4081 ttggtacaaa atatccagat acagtatccg caagtttagc aataggtgct tttgtacctt
     4141 gtgcatcttc aactaacttt attatttggg caagagcagt atctccacca attttttcag
     4201 ccttaaactt aataacacca tttttattaa tactagctcc tgtcacttta cttccaacat
     4261 tcttttctac tggtatgctt tcacctgtaa gcattgattc atcaactgat gtatatcctt
     4321 ctattacaac tccatctaca ggtatttttg ttccaggttt tactaataat atatctccta
     4381 tttctacctc ttctatagga gtttcaactt ctttaccatc aaccaacact actgcagttt
     4441 taggttgtag ccccataagc tttttaattg cttctgatgt ttttcctttt gattttgatt
     4501 ctaaatattt accaagtaag ataagtgcta ttattattcc tgcactttca taatataact
     4561 gatgatgatg cataccttga atttgaccat ttgctatttg tattgttgtg tataaactat
     4621 acaaaaatgc tgctaatgtt cctattgcaa ctaaagaatc catattaggg cttaaagaaa
     4681 aaagtgcttt aaatccattt atataaaatt tataaccagc tatcattact ggtattacta
     4741 aaattaactg aattaatgcg tagttaaaag tatttttcat tggatttata atttctggca
     4801 aaggccatgg ccctataggc tttattatca taggtcccat tgctatataa aacaaaggta
     4861 ctgcaaatac tattgcaact ataaatttaa caaataaaga cttcatttcc ctttcttttc
     4921 tcaatttatc ttcatccaca tcaaccttat ttcttacctc ttctattggt ttatatccag
     4981 ctttttcaat agctgctttt atttgagata actttacttt tgatggatta tagtctatat
     5041 tagctttatc tgttgcaatg ttcacactaa tactttctac tccatccaat ttttttacca
     5101 ctctctctac agcttttgca caagctgcac atgtcattcc atcaattttc atatcaattt
     5161 ttttattact ttcttccttt ataattccat atcctgcttt ttctacaact tgctttatat
     5221 catcaaaatt aaccttagaa ttatcatatt ctattttaag tttttcagta gctatattta
     5281 cactttggtc atacactcca tccatcttct tagttactct ttctactgcc tttgcacaag
     5341 ctgcacatgt catacctgta attttgtaac tttctaccac tttatttgaa ctcataataa
     5401 aatcttcctt tctttcaaca tattttcaac taatttgtaa cgttttattc tgatatgtag
     5461 tattgataaa ttatttattt agaaatctat atttttatta taccccctgt aggtatatta
     5521 aatcaatctt ttttttataa ataaatgtat tagttatatt tatttgtatt taataaaaaa
     5581 gtatacttat aattaaatat atacataaaa atagagcata taaattgttt aatatttata
     5641 caatttatac gctctattta ttataattta tattttattt aaaatttatt ctttacaagc
     5701 ttcaaaaaac tccgcttctg tttcctttat ttcaagctca ttgtctatta ttccaacagc
     5761 ttcttttttg aatgctctac actgacctat acaaccagtt tttacatttt cttctccaac
     5821 caaagttttt agcttattta catccacatt tgaacagttt ggacatactc ttatcatatt
     5881 taagttcctc ctaattaatg tctaattaat acttttatac ccaaatataa actttataaa
     5941 agtttttttt atataaattg ttaccataca taccatattt atcctaatat aagtattaca
     6001 cattaatttt atatattatt aatactacat gtacggtggt atctgttgtt ttctcactat
     6061 ttccaattcc ttaatttcta aagacttaat tacatttact ttatagtttt ctttagattt
     6121 tatatacaaa acatcttcta tctttttacc ttcaataaat ttatgagacc atttaagaag
     6181 ttcttcaaaa ttgcaaactt cttcttttac aaaagtatca ctttcacttg caaaatattt
     6241 aattattatt ttggttactt ccaacatata tcatccttta ctcttttatt aatcttttca
     6301 tctattaagg ttattatttg tctaaaaaat ttttttaaac agaataattt tcggatataa
     6361 aactaacatt tttatccaat ttgaactata ttaatacaat ttaatatatt cctccttgta
     6421 cctaataaca tattgtgcta taattaataa gttattttaa tcgaagggag caacaaaaat
     6481 gtcacaaaaa cataaaatta taaatatcgc agttatagcc cacgttgacg ctggaaaatc
     6541 aacattggtt gatgctttcc tttctcaaag tggtgttttt agaaagaacg aagtagttaa
     6601 agactgcgtt atggatagta acgaccttga aaaagaaaga ggcataacta tatattcaaa
     6661 aaactgtgca ataaactatg aggattacaa aataaacata gttgatactc caggacacag
     6721 tgacttttct tctgaagttg aacgtgttat gaaaactgtt gacacagtta ttctattagt
     6781 tgatgctagt gaaggcccaa tgcctcaaac tagattcgtt ttacaaaaat ctttagagtt
     6841 cggtttaaaa ccaatattat ttataaacaa gattgataaa aaagaccaaa gagcggaaga
     6901 agtagttaat gaagttttcg atttatttgt agacttaaat gcaacagatg agcaatgcga
     6961 atttcctata atatatggta ttgctaaaca aggtattgct aaactggaaa tggatgatga
     7021 tagcgaagaa ctttctcctc tattcaaaac tattgtaaat cacgttgaag cttatcctga
     7081 ttacgataat gaacctctac aattccaaat atcagctctt gcatatgatg attatgtagg
     7141 tagacttggt ataggtagaa tttacaaagg tactcttaaa aataatacac aagttgctat
     7201 atgtagagaa gattctgttg tatctaaggg aaaagtatca aaactttctg tgtatgaagg
     7261 tttaaaacaa gttgaggttg atgaagctac tagtggagaa atagttgtta tagctggtat
     7321 acctgatatc tctataggtg agactatatg cgatttagat agtccactac ctatggaaat
     7381 gataaaaata gaagagccta ctctttctat gaacttctta gtaaatgact ctccatttgt
     7441 tggaaaaagt ggaaaattcg ttacaactag acatttgaaa gatagacttg aaaaggaact
     7501 tgaagtaaat gttggtctta aagttgaacc tcttgatact actgatggat ataaagtttc
     7561 tggacgtgga gagcttcact tatctatatt acttgaaaat atgagacgtg aaggttatga
     7621 agttggtgtt tctaagcctg aagttttaat gcataaagaa gatggaaaac taatggaacc
     7681 aatagaaaga gttgttgtaa actgtcctga agtttactct ggtactatta taaatgaatt
     7741 aaacatgaga aaaggtatga tggagtctat gtcaatagaa ggagactatg taaaaataga
     7801 gttcttagca cctactcgtg gtcttttagg atatcgaagt gaatttataa atgctactcg
     7861 tggagaaggt actttagttc gttcatttga aaaatttgaa gaatttaaag gagaaatacc
     7921 ttcaagagga aatggtgttt taatagcaca aggacctggt gttactatgg gatattctct
     7981 taatgcctta agtgatagag ctgtaatgtt cgtagaccct ggtgtagaag tttacgaagg
     8041 tatgataatt ggaatgaatt ctagaaaaga tgatatggta gtcaaccctt gtaaaaacaa
     8101 gaaaatgagt aacgtacgtg cttctggttc agatgatgct ataaaattat ctcctcctag
     8161 aatatttact cttgaagaag ctctagaatt tatagaagat gatgaattag ttgaaattac
     8221 acctgattct ataagactta gaaaaagatt cttaaatgaa catgatagat taagatataa
     8281 taaatctaga caaggtaaat aaaacataca tttacctcta gttagcaaaa tagccatata
     8341 atactgaaaa attatttcag tttatatggc tatttttatt tgaaatttat actattcaac
     8401 atttatataa ttagctgctt gaacagctgc aatagctcca tctgatgctg ctgttattat
     8461 ttgacgtaaa aacttagttc tactatctcc tgctacatat acaccttcca cagatgttgt
     8521 acaagattca tctgaaatta tatatccacc ttcatccaaa tcgagaacat tttcaaacat
     8581 tttattatta ggtttaagac ctatagcaat aaaaatccca ctgacatcta tagttctttt
     8641 ttcttcagtc tttaagtttt ttacctctat tttcgataca gtcttttctc cttctatttt
     8701 ttctacacca tgactgtaaa gtatctcaat attctttctt gctttcacag atttttccaa
     8761 cacttcttca cctctaaaac tatctcttct gtgaattaaa tacacctttg tgcaattgtt
     8821 ggctaaaaat aaagcatctt ctaatgcagt atttcctcca cctactatag caacttcttt
     8881 atctttaaaa aatgctccat cacatgttgc acagtaagat actcctctac ctgtaaattc
     8941 ttgttcccct acacaaccta atttacgtct ttcaactcca tttgcaagaa taacagcctt
     9001 tgctttatgt tcagctgaag aagtttttac aatctttatt tttccctcta gatttatttc
     9061 ttcaacctca tcaaactgaa tatcaacacc ttgagcaact gcttgattgt atatattatt
     9121 agaaaattct accccagaaa tcttctgaac tgctgggtaa ttttctacct cagaggtact
     9181 tgcaacttga cccccataaa tatttttttc aaatactgta acacttagcc ctgctctcat
     9241 agcataaatt gctgaagtta aacctgctgg tccagcacca attacaatga tatctaccat
     9301 aacgtttacc tctcttatat attattctca ttactcttat actttactat tattatccat
     9361 atatactata aataaaacat tattttttat taattaactt tattttacat atatataaaa
     9421 aaactgcaaa taaaaattaa cttttattta cagttctcac ttatttatat aattcaaaac
     9481 cttattggtt atcatttaca gtgtcttcta atatattgct ttctgatata tacgataaaa
     9541 ttgaaagtcc atacataacc aaaactaatg ctgctgttat aagtactatt cccatattta
     9601 atacctcctt ttgtttacag tatactatta ttatgtgaaa tatttatgaa tttaatttga
     9661 atatatatgt aattttacac tgacaatttc ttcaaattaa acattattaa ctatatactt
     9721 ttgttgaacc aattatgatt aatagtttaa atattagcac tatttactta tatttatatg
     9781 atataccata taattacatt tttcaaatta aagttttgta aacttttttt gtaatatagt
     9841 gtaatataaa attgtaatat tacagatatt taatagttat cttttgatta cttttactaa
     9901 aaacagcttc atcactatga aaatctaggt ttttaagctt ttaaaaaagt taaaaaatta
     9961 tttttctaat actcaatttg attacaattt ttttacaatt taaaaaatat tttttccaaa
    10021 tttttatatt aatacttgac tttgtctgtt ttataaacta gaataattaa taatattaag
    10081 aatattgaaa ggcattgatt aggaagagta aatctgaatc gattaccaga gaaggaaact
    10141 actagctgaa atgtttccat aattagaagg attgaaaact acctatgagc ttctatctga
    10201 agttatcttt atgattttag taggaataga cgttttatta cttacgttaa agtatcaagt
    10261 ggattttttt aaatcaattt gggtggaacc gcgggaaata gattctcgtc cctttcttag
    10321 ggatgagggt ctttttttat tacctaaatt cagtttttaa aatattctgt atctaactta
    10381 attagctaat taaaaattta aaatatatgg agggttataa aaaatgtatt attcaagtac
    10441 aagaggcacc gaagaaaaag taactgcatc acaagcaata ataaaaggaa tatcaaatga
    10501 tggtggtctt tatgttccaa gtaaatttcc caatgtaaaa aatgaactta tagatttagt
    10561 aaatttaacg tattctcaga tagcattttt tgtacttagt aaatttttat gtgattttac
    10621 tgaagatgaa attaaaaatt gtatagaaaa tgcatatgat gaaaagtttg attgcagtag
    10681 tatagctccg ttaaataaag taaatgatac ttatttcttg gaactgtacc atggtccaac
    10741 tttagcattt aaagatatgg cacttactat aatgcctcat cttcttaaaa catctataaa
    10801 gaaagataac ttagagaaag atgttgtgat tcttactgct acatctggag atactggcaa
    10861 agctgcactt gagggattta aagatataga taaaataaaa ataattgtat tcttcccaga
    10921 agatggtgta agtccagtac aaaaacttca aatgaaaact caaactggaa aaaatacata
    10981 tgtagttggt ataaaaggaa attttgatga tgcacaatca ggtgtaaaga agattttttc
    11041 tgataaagaa tttaatcaaa aattattaga taataattat atattatctt ccgcaaattc
    11101 aattaatata ggaagacttc ttccacaagt tgcatactat ttttattcat atatgaaatt
    11161 agttgataat ggggaaataa atttaaatga taaaataaat tttgttgtcc caactggtaa
    11221 ttttggtaat attctagctg gatattatgc caaacaaatg ggtcttccaa taaacaaatt
    11281 gatatgtgca tcaaatgata ataatgttct ttatgatttc tttaaaactg gtgtatatga
    11341 taaaaataga acattgaaat taactacttc tccttctatg gatatattaa tctcaagtaa
    11401 tttagagcga ttactgtttg aaatatcaaa tagaaatact gatattgtaa ataaactgct
    11461 atcagacctt aatgataaag gagtttacaa aataagtgag gatatggaaa aaaatttagc
    11521 ctcattccat ggagaatatt caaatgaaga agaagttaaa aacacgataa acagcgtgtt
    11581 taaaaattat aattatttga tagatactca tactgctgtt gcatataatt gttatgaaaa
    11641 atataaaaaa gaaacttctg ataacacaaa aactgttatt gtaagtactg caagtccatt
    11701 caagttttct gaagatgttc taaaatctat agattgtgat tttaaagacc ttgatgactt
    11761 tgctataatt gatagattat caagtatttc taaaatagat ataccaaaac ctattaaaaa
    11821 tcttaaaaat gcagaaatac tacataaaga tatttatgaa aaagatgaat taaaactagc
    11881 tataaaaaaa ttcttaaagg tataggtgat tattatgtta gagattatag ttcctgcaac
    11941 aagtgctaat ataggtccag gatttgattg tcttggaatt gcgttaaata tatacaataa
    12001 attttatgtt gaagaaattg aaaatggtct tgaaatagaa ggttgtgaag acgcttacaa
    12061 aaacgaaaat aacttagttt atacatctat gaagtacttt ttcgatagag ttaaaccaga
    12121 aaaaatacct actggtatca aaataaaaat ccaaagtgaa gtgcctatat gtagaggtct
    12181 tggtagtagt gcctcttgta tagtagctgg cgttatagct gcaaatgctc tatcaggtgc
    12241 taatttagat aaaaatcaat tactaaatat agcttcagaa atagaaggtc acccagataa
    12301 tgttgctcct gctattttag gaaatatgat tgtatctgtt actgataatg aaaatataca
    12361 ctatgatatt ataaaaattc ctgaagaact taaattttgt gcaatgatac ctaatttcaa
    12421 attatcaaca gaaaaagcta gaggtgtttt accaaaggaa ataccatatt ctgatggggt
    12481 attcaatgtt agtagagttg ctttactagt atctgcttta ataaacaaaa actttgaact
    12541 tcttaaagta gcttgtcaag acaaattgca tcaagattat agaggaactc taattgaaaa
    12601 ctacaatgat attgttgaaa aatctgaaca attaaatagt attggagtat ttttaagtgg
    12661 agctggacct actataatgt ctttaataag agaaaatgat gatagttttg tagataatat
    12721 gagaaattat ctacaaaact taaaatctga ttgggaaata aaagagttat attgcgattc
    12781 taatggagct gttttaaata tattataatt atcgtcttct atacaaaata taactactct
    12841 tttattataa tttgtagtat aataattagg actaggtaat aatattaagt attataatct
    12901 agttctttaa acatgtttac attgaggagg gattatcata aaagagttaa taattagaga
    12961 tttagttgca aaagttccta taattcaagg tggaatgggc gttggtatat ctaggtcatc
    13021 actagctggt gcagttgcta agcttggtgg tgttggtgta atttctggag ttcaaattgg
    13081 atatgatgag gaagattttg aaactaatac tataaatgca aatttaagag ctataaaaaa
    13141 acatatttct aaagctaaag aaatctcaaa tggcggtatt attggtatta attttatggt
    13201 agctatgaaa gaatatgaaa catacgtaaa ggaagctgtt aaagctggtg tagaccttat
    13261 aatatccgga gctggattac ctaacaagtt accatcatta gtaaagggaa gtaatgtaaa
    13321 aatagcacct atagtttcaa ctgcaaaagc tgccaatgta attttaaaaa tgtgggatag
    13381 aaaagagaaa actactgctg acttaatagt tgttgaaggt ccaaaagctg gtggtcacct
    13441 tggatactct aacgaggaac ttgataacat agattctata gactatgata aggaatttgt
    13501 tgaaatttta aaagttgcaa atacttatgg agaaaaattt ggtaaaaaaa taccagtagt
    13561 tgctgctggt ggtataactt ctagtagtga tgttaaaaaa tatatagaca tgggtgcaag
    13621 tggtgtacaa gttggtacaa gatttgttgc tacttatgaa tgtgatgccc atgagaactt
    13681 taaaatggca tacataaatg ctagtgaaga agatgttcat atagttaaaa gtcctgtagg
    13741 tcttcctgga cgtgccataa gaaataaatt tatagaagaa gttaaaataa atcgtccaga
    13801 aataaagaag tgctataatt gtttaattcc ttgtaatcca aaagaaacac cttactgtat
    13861 ttctcaagct ctaatcaatg cagttaaagg agatgttgaa aattcacttt tattttgtgg
    13921 aaatgatgcc tataaaattg acaaattaag cactgttgaa gacgttatca atgaattaat
    13981 ttctgaatta taatttaaag aaatctaaat taaaatttta tcaagctaag gagtttaaat
    14041 acgttattta ttaatctgta tcaacatatt tacttcctta gcttttttgt gccaatttcc
    14101 ttttatagag attttattta attagagata gtattaacct ttataactaa gcttctttta
    14161 caagtacatt ggttatttcg gctatatata aagtgtgata atctttttgt ggataccatc
    14221 ttccatctat accttcagca ataaaacatt gaggttccag tttctgacta tacatttttt
    14281 tacatataag agccattttc gcttctttaa aataaggtgt attatttaag tgttctatat
    14341 taaatccaac ctgtgatatc ttatcttctt ctctaccaga tacttttcca caatatgaaa
    14401 gctctttacg aaaatcttca tcaaaaaagg taagagaaaa tttatctgta ttatctataa
    14461 attccttagt ataacgctgt ggtcttatta ctacaaaagc aacatctttt ccccacataa
    14521 ctccaagccc tccccagcta gcagtcattg tgtttacttt gccttcattt tctgctgtta
    14581 taagtgtcca atctttacct atcaatccaa atggattact tttaatctct tctgccaaaa
    14641 tctctttaaa atcactcata tctcttataa cctctcattc tcttatattt atattccttt
    14701 tattttcgtg ataaattata aatgaagtct agttttgaaa ataaaataaa tttttttaaa
    14761 tatattatta caaataagta aatatataga tacactctta ttttttaata tatttaataa
    14821 tttcactcag aatatatata ttctttattc aaattaaata taacctatat attttatatg
    14881 taaattatga taaaaaaatt atttaatcaa atcaaaactt gatttatata cctggaaaag
    14941 gtattatatt aaagagtgct taaaatacgc atttcataaa taactatata aaaaataata
    15001 aataaggaga gtgatgggca atggatacta gtccgttgcg gagagaattt tttacattct
    15061 catcacttaa taatatctaa aatcaaaact aatacatata ttcagttata taaattagtt
    15121 aattaataga tactattaaa tgatgagatt tatataaaac tgaataaagg atgtgttgcc
    15181 atgataagat attacaaaac tatagattca aaattagaga aacttagttt ttttgaagat
    15241 ggctgttgga taaatcttgt tgaacctaat catagtgaaa tcaatgaaat ttctaattta
    15301 ttaaatatag atgtagaaag catagaatct gcactagatg aagaagaacg ctcaagaata
    15361 gatgttgaag acaatcatac tcttatactt atagatatac cagtagacga aagtgactct
    15421 aattcttctc attatactac aataccctta ggtattatac tgactgaaga agctattgta
    15481 acagtttgtg atgcacaaac taagatttta aacgacttta tagttggtca tattaaagat
    15541 ttttttacat ttaaaaagac tcgcttttta cttcaaattc ttcataaaaa cgcagcttat
    15601 tacttgcatt acttaagaaa aataaataaa atgacaatca taatagagcg agaaatttac
    15661 aaatcaatga aaaacaaaga attggttcaa ttattagaat tagaaaaatc tttggtatac
    15721 ttctctacat cactaaaatc taatgaactt gttttaaaca aaatggttag aactgctggt
    15781 ataaagaaat atccagatga tgaagaccta ttggaagatg ttatagttga aaatagacag
    15841 gctcttgata tggctaaaat atacggagat atattgagta gaattatgga tgctttcagt
    15901 gcaattataa gtaataatca gaataatgtt atgcaaattt taacggtagt tacactaatt
    15961 ttctcaatac ctacaataat atcaggattc tttggtatga atgtcatcaa catgccgttt
    16021 tctgatgacc caaatggatt ttggataata cttcttattt ccgctataat atgtatagta
    16081 attacatttt tcatgtcaag aaacaagcta ttataaaata ttaataaaaa agccattaga
    16141 actaattgat tttcatttat cctaatggct tttttatatt taaatatata taaccttata
    16201 atacttttta attatcatgt tcttcatcta taatcatttc agtttcaagc ccttctagca
    16261 ttgaatctaa actttctttt atatttagta tataaattgg tacatactct tcttcatcta
    16321 ttacctcttc ttgcaactta aatggaggaa ttaatacttc atcaaagtct atatttaaat
    16381 taggaaagtc ctctactatc tcttcacaat tatcgtattc ttcatttgct aaagaaatgt
    16441 acatatctag gctcttttta taataaagac ctgcaagcat gtactcacac ttcttacttc
    16501 catatttaat accttcttta taatatttct cagcttctgc gtcatcattt aattttaaat
    16561 aaatttgacc taaattatat attgattcaa cacaaccttg tgccctagcc ttttcatacc
    16621 aaaatttaga atttacatag tctttataaa acatatcata aattaatccc accatatgtt
    16681 gagcatacac attattttca ttggcaggag tatcaaacat cattttagcc tcttccaatt
    16741 taccttctct aaaataaatt ctacctagat gtatacgagc attcatatgg tttttgctac
    16801 ttgccatttc aaaatacttt ctagcatttt ttgtatttcc taaactctca taaatacatc
    16861 ccaatctata actagacctc gtatccccat tttcagatgc tttcttatac caacttatgg
    16921 cttcttcaac attatttaaa tcttcataga tatttcctaa tttgatttga caagatacat
    16981 tatttggaat ccttgaataa tacgaaatcg ctttttctat atcttgattc tgataatata
    17041 aatcccctag attctcaagg gaacttttgc atccaacagc tatagcatcc tcataatatt
    17101 taatagcatt ttcataatct ttttcttcaa aatatatacc tgccagatta ttttttgctt
    17161 ctgttatatc atcttcagcc gccattttat aataagtttt tgctttttct atctcatttt
    17221 ctctattgta taaattagca agtctatact tagaaagtgt atgatttttt tctattgctt
    17281 tctcataata ataaattgca tctcccagtt cttcttttct atcatataca tatgcaagtc
    17341 tatactcaga cttcacatca tctctatcag cactcttttt ataatatttt tctgcatctt
    17401 ctaaattatc atttatctcc ataatcatac ccaagttaaa gcaacctttc atatgccctg
    17461 acttgtacaa ctgtttatat aaactcactg ttgatttatt atctttcttt tttccattta
    17521 atattgctaa attatatttc gcatcatcat ctaaaagcac agaacctttt ttataatatt
    17581 catatgcttc atcatctttc tccaaaaaag tatataatac ccctaaatta aaacaagctt
    17641 tacctaaatt attgtctgct gctgatttta accatttttc acatcttata aaatctttca
    17701 ttttaaaatg gcatacacct aaattatttt gtgcttgcaa ataacctaaa tttgctatct
    17761 tttcatacca atatatagca tattcataac catctaactt atagtacata ttacctaaat
    17821 caaaagcagc atcttcactt ccacttttat atgccattga ataccacttt tctgcttctt
    17881 taaattgttt tttactttca tatatatttc ctaaagtata ttgagatttt acataattat
    17941 ccaatgcagc actcttatac aactctattg cgctttctat cttacccatc ttttcaagga
    18001 gggcaccctt agtatgtacg actttcgggt cattagatat attttttatt ttttttatag
    18061 aaaattttgt atttttcatt attcgctacc tacccatttt ataaaatata ttctctcaaa
    18121 cattattata cattataatc tataattaat gctataatat tgaattttta ccttttgtca
    18181 ctatattgta acattaaatt ttaaatttta taatcattag attttattat gtaattggta
    18241 tataatgtat atataagggg agggacattt tatgaatttc agcaatattt ttattcaagt
    18301 tgcagtttta tttataatta ttttagttgg gtattttgtc agaaaattca acttattaga
    18361 tgaccactgc acatctaagc tttcaacttt gacaatgaca gtttttttac cctcaatgat
    18421 aattagctcc atgcaaatta actttgatag taaaatgata caaaaaatac tattgttatt
    18481 atttacatct ttgattatgt atatagtttc aattataatt gcatttttgt taaaatacat
    18541 tttaaaatgt aatgataaaa aagatttggg aatatatcag tatatagttg ttttttcaaa
    18601 tgttgctttt atgggttatc ctgtaattga agcagttcta ggtcatgaag caatattcta
    18661 tactgcaata ttcaatttgc cttttaactt attttctttc actttaggaa tttatctttt
    18721 atctaaaggc agtacaaata aaagtttttc aataaaatca cttataagcc ccgctacaat
    18781 agctattgtt attggacttt ttttatttgt aacaggactt aggttacccc aatttataaa
    18841 cgagccactt gagatgttgg gaagtataac tacaccaata tccatgatta ttattggaag
    18901 tttacttgct aattcttcag ctctcgattg ttttgtcaac aaaaaattat atatagtcac
    18961 ttttataaga ttattgctgc ttcctgtgat tgtatatttt attctaaaag gatggataaa
    19021 tgataagatg attttggcta taccagtagt aatttcttca atgcctgctg ctgcaaatac
    19081 tgctataatg gctaatcaat atgactccaa tataacacta gcttcacaat gtgtgttttt
    19141 tacaacacta ttttcagtta tatctatacc ttttataagt attttactct tatcttgatt
    19201 tattttttta tgtattatat aataacatat tcaataaatt acaaatataa acattttatt
    19261 gtagtatatt gatggaattt tttcctagat atttgtcaat aatatctata tgtattatag
    19321 aataggaggc ttaaatatgg atatggattt actctttaaa atagtatttg ctatagttgc
    19381 tataggtgtt tctgtaaaaa tcatcaaaac tgttgctagt ttagctttta aaatagcgtt
    19441 gatattgcta ataattttat ttgtatatag aatgtttttg taaacattta aaaataagtt
    19501 ttttaataaa atagagaagt aaaatagatt atctttaatg taaatttttt attaaagaca
    19561 ctctatttta cttctctatt agttttttta aattaaattt ttattatatc ttcccataat
    19621 ataaacatct tcaaattttc catctctgat tacagcatat tttttagttc cctctatttc
    19681 aaaacctagt tttttatata aatttaatcc cttttcatta tccacaatta cttctaatcc
    19741 tactctagct aacataatcc aattatctgc tatgtctaaa agttgttcca taagcttttt
    19801 acctactcct cttccctgat aattctctgc aacacttatt cctatttctg cactatgtct
    19861 caatcgtgga gaagaattta catgtaaccc agcaaagcct attacatctt tttctccatt
    19921 attattagtt tcagctacaa acatataatc attttctccc aaagaagcta acatagattc
    19981 agttttatcg actctgtcac tcattaatgc caaagtattt ctcataacac tgtatgttct
    20041 tctaatttca ttaaaagctt gtgcatcttc tcttcttata ggtcttattg ttatatctat
    20101 aggcttactc atattggatt ccccctcaaa cataatcttt atttttaatt aaaattttac
    20161 atctttattt tatacttttc aaatctatgt atgcttctat ctgaggtaca tatatcatat
    20221 tatcttttat atgtgtactc ccaaattctt ttaattctgt accttcttta tccttagtta
    20281 ttttatatct gatggattcc atactttcaa ttatttcagc atgaaaaaac ataccttcat
    20341 attgtttaaa tctaaaatta aaatcgtctt tagtaagttt tattatcata tttttatcta
    20401 ctccttatat aattaatatt tttcttatta ttagttgtat acatattgct tattcatatt
    20461 aatatattat aacttatcat ttatttagta taaagttata aatagatata tttatactta
    20521 ttttacaatc tttcttcaat tgatatataa tatgtttata taaactaatg tatgtgaggt
    20581 gaaatatgag caaaaaaaca aaatattttt ctttaattct ctttcctatt gctttgcttt
    20641 taaattttat agccagcaaa gttccaaata ttgttgaaaa atattactcc caatttatag
    20701 ataaaataat tgtacaagta ttgagtaaag tttcaggaat ttttccattt tctctctatg
    20761 aaattacaat gtacataata gttatatcta tcttcttatt tttatgttgt actttatcta
    20821 caatttttaa taagaaaaaa aaattaaaca tatttttaaa aaattctatt ttaaatatat
    20881 tatccattgt atcaatagtc tactttcttt ttgtagtgct ttggggaata aactataata
    20941 ggattccact agaaaccaca cttataaata actataattt agaaaacaat acctctatcc
    21001 aatcaaaaca acatagtgtt aaagagctta ctaaattata taaatttctt ataattaaag
    21061 caaatgaaac tagaaaactc acattacaag ataaaaatgg tattgtaaaa tctaatacag
    21121 attataatgg tgttataaat agagctcaac taggatacga taatatcttg gatatattac
    21181 ctagtgttag tggtagttat tctaagccta agtatattat ttcatcaaat ctaatgtgct
    21241 atacagggat aactggcata tactttcctt ttacaggtga ggcaaatgta aatatagcaa
    21301 tacctgactt gtatattcct tgtacagttg aacatgaaat ggcacatcaa aggggatttg
    21361 ctagtgaaga tgaggctaat tttatagcgt atcttacttc tataaaacac cccaatattg
    21421 attttaacta ttctggatat attttagctt taaattatac tgcttctgct ttaagtaagg
    21481 ttgattataa tgcatatgtt gatatttctg ctggtatttc agattctgtc cgtagagatt
    21541 taaaaaatga aagtaaattt tggcaaaaat atgaaggtaa aattgatgag atttctaatg
    21601 agtttaacaa ttcttactta aaagctaatg gcgttactga aggcactcag agttatggta
    21661 aaatggttga tttattgcta acttattatg aattatatcc atataactaa acactacaat
    21721 tcaaaacttt attcatatac agctggtatt aaatcagctg ttttctattt aaataaatta
    21781 tttagctcca agcaatctta tataatttga aaatacttat actatctgta taacatttca
    21841 attctaacta ttttagttaa aacatttcta ttatcttttt taataaatat tttaactaaa
    21901 atttttaaaa cataaaactt ccacattatt tcactatcta tataaaaaga taaaaattta
    21961 catataaaat tacataacta aaaaatcata aatttataga aaacatatat tcaaaataaa
    22021 aaagcatgta tcaaaacttg acacatgctt ataatcttat gtatatatgc cattttgtca
    22081 caataaaaat ttccttgtaa cactgacatt tttaaacaaa atagttctta tttaattaaa
    22141 ttaacattag ttaaattcgt acttatttta ctatcattaa acattactta tagtaatttt
    22201 ctaatacact atttgaaact tccttccctt gaaaactttt caaccaattc tcatatgctg
    22261 aatttttcca tacactacca tcattaaatg ttacttgttt tacacaagat ataatgtact
    22321 ttacaccatg ctctccagtt gattgtttcc atttatcaaa caataaaaaa gcatcatttt
    22381 gattcttacc tggtgctatt gcattttgct ttgcatattc tttctccatt tgtttccatt
    22441 ctttcaacca attttctacc catgccttgc cttgttgttt ttcaaacata cttattatat
    22501 cctgtggtgg tgattgttgc atttttctat aagtatgtga atatgatttt ggagacacag
    22561 gagatatgcc tgtaacaata ccataatcta caccagctgg gctaaaccca acacttccta
    22621 cttcgccatc tgctgccaca ttttgagcat cccagtatag ctcaagtggt tttccatttt
    22681 tatcatatgc taagcacgta atttcataat ccataattgc tttttcactg ctatttgtta
    22741 agcttataac attgctaggc caatgatatg gagtatcatc atactgtatt ttgctattat
    22801 ttataaataa tggaatattt tcattgtaaa caagaccttt actactttga atatctgata
    22861 ctttctttgt gatagtactt actgtacttg ctaagtatac acttgttttt tctgaattgg
    22921 tcgtactaag agaaaatgtt gttgtcgttc cagtaatcag caaagcaaca actaaaatag
    22981 gtaagctaga tattttttta tatctcacag ttcttcaccc cttcttctat taacttataa
    23041 taaaacaatt taccaaaaca ttaaaatcta tgttaacata atttaccaga tgttctagta
    23101 actatatcct atcatagtta ctatcaagtt tcaatactat tgatggaaat tttcactata
    23161 ttaaatcttt ttttaatttt ataaatttac aatataattt aactcataca tatatagtca
    23221 aattagagta taagtttctt acatttaatg aagtttataa aataaaaaat gactagataa
    23281 ttaaatactg taaataaaaa ctcattacaa aagtatttaa aaatctagtc aattaatata
    23341 tatctaaatt gtatactata atttctcaat ctcttctagc aactcatcaa ctaatttgtt
    23401 accatcaatc attctcacta tttcaccctt tttaaataaa aggccttcac ctttacctcc
    23461 agcaatacct atgtctgctt ctctggcttc accaggtcca tttacagcac agcccataat
    23521 tgcaacagtg atattttttt ccatactacc aatcttttct tcaacctcat ttacaacact
    23581 aattaagtct atattacatc taccacatgt aggacatgat ataactttaa tcttatcatt
    23641 taaaagtccc aaacttctta aaatttgttt accaacaata acctcttcaa cagggtcacc
    23701 tgttaaagat attctaacag tatctccaat tcctttaaga agaagtgctc ctacccctat
    23761 agaagacttt attgttcctt tgtgaacact tccagattct gtaattccaa tatgaagagg
    23821 ataatcaact ttttttgata ttaattcata tgcatcaaca gttttataaa tatcggatga
    23881 ttttagagat ataactatat tatgaaaatc taagtcttca agaatcttaa tatgtcccat
    23941 tgcactttca actaatgctt cagcagttgc agagccatac ttttttaaaa gttctttctc
    24001 taaagaacct ccattgactc caattctaat ttttaaattt ctttccttgc atttctcaac
    24061 taccatctta actctctcta tacttccgat attaccagga tttattctta ttccatccac
    24121 accttgttct atagcttcaa gggctagctt ataatcgaaa tgtatatctg caataattgg
    24181 tatatttaca ctagacttta tctttgctat attcttagca gctttaatat caggaacagc
    24241 aactctaact atatcacaac cagcttcctc tagtctcttt atttgagcta ttgtagcatc
    24301 tgcatctctt gtatcagtat ttgtcataga ttgtatactt ataggatttt ctcctcctat
    24361 ttttacagtt cctacactta cttctctcgt ctttcttctc tcgtaactca tattccacct
    24421 ctatatatta ttttatattg aatctcttta aatattaaaa tattataacc tacatgtata
    24481 ttataaatta aaaagctatc tagttaaata agaataaatt tcatacataa aaattaattt
    24541 attcttattt aaaactacat agcctatttt cttaaaatct ctaaaaaact aaatcattga
    24601 aataatctta gtatatcttt atatgtgata aaaagcataa ataacattaa agctccaaaa
    24661 ccaacaacat ttatcatgcc ttctttattt gggtcaagtt ttttaccacc tctaacagct
    24721 tctagtaata gcataagtat tctccatcca tcaagcgctg gtattggtaa tagatttact
    24781 atacctaaat ttaagcttat gacagctgct aaatacacta catttatgat gcctgtacga
    24841 gcagcatccg ataccatacc aataacacct actggtcctg ctacagcatt gccaatccct
    24901 cctggtacac gtcctgtaat catttgacct agaaatgtta gcatctgttt tgtcatatct
    24961 acagtagttt tacatgcatt tactattgac ccccaaaagt ctttttccct ttgtggttga
    25021 atccctattt catactttcc attgttattt ttaggtgtta catttacaac tttatcactt
    25081 ccatctctag ttatactaag ttttaattct ccaccagaag aagtgtttat tatatttgca
    25141 acttcatccc aagtcttaac agaattacca ttaattttat ttatcttatc tcctacttga
    25201 agccctacag cctgtgcagg agtatctggc attatctttc ctaatttagt cgttggagaa
    25261 cctatataca aaaatactgg tactaaaagt attgctgcta atattatatt gaatattgga
    25321 cctgctacaa tagtactaaa tctttgtaat atagacttgt ttccaaaaga atttggactt
    25381 atttgctctt catcttcacc ttccatactg acatatccac caattggaag tgctcttata
    25441 gaatactctg tatctttttt tacactatat atcttaggcc ccatacctat agaaaactca
    25501 tttactttga taccacttct ttttgcaaat ataaaatgtc ctaactcatg tattaataca
    25561 attatactaa atagtattaa tgcggctatt atagtcataa attcaccttc ctattttttt
    25621 atcagatttg caacataagc tctactccat ctatctgttt ctaagatttc ttctaatgtt
    25681 ggttcactta tgctactatg aacttctaaa gtcttctcta tgtaatatgg tatgtcatag
    25741 aaaccaattt tatcctctaa aaattcactt actaaaactt catttgctga atttaaaaca
    25801 gaagaataag ttcctcccat ttttaaacac tcatatgcca attttaaaca tggaaaagtt
    25861 tctaaatctg gttcttcaaa agttaaagta ctaaattttg aaaaattcat tctttcaaag
    25921 ctactttcca ttctatctgg atatgtaaga gcatactgta ttggtagtct catatctgga
    25981 catcctaatt gagcaattat tgagctatct gcatactgca ccattgaatg aattatgctt
    26041 tgtgggtgaa ctactacatc aatattttct tgttctaccc caaacaacca tctagcttct
    26101 atcacttcaa gtcctttatt cataagcgtt gaagaatcaa tacttatttt tcttcccata
    26161 ctccaatttg gatgcttcaa agcttcattt ttagttatat ttacaagttc tccctttttc
    26221 tttcctctaa atggaccacc agatgctgta agtattatct tttctatatt ttttttattt
    26281 tctccattta gacattgaaa tatagcacta tgttcactat caacaggaag aatatttaca
    26341 ttgtattttt ctgcttcttt cattacaagt tcaccagcgg ttaccaacgt ttctttattc
    26401 gctaatgcta tgtctattcc cttctttata gcacaaagag ttgggactaa tcctatcata
    26461 cctactacag cagttaaaag gacatccact tcatcaagtg atgatattat ttttaatcct
    26521 tccattcctg ctaagacttc tatttctata tttttaggca acatttcttt taatttcaat
    26581 gctttatttt cctcaaaaac tgttacatat ttaggtttaa actctactat ttgttctagc
    26641 aataattcaa tattactgtt agctgatatt gcaactatct caaacttatc tctatgttct
    26701 ctaaccacat ccaaagtttg tttacctata gagcctgtag aacctaaaat tgatatcttt
    26761 ttcatataat aatcctttct aataataaat ataccctatc aaaacattat aacactacta
    26821 aaacaattat ttttactatt catagaaatt tcatatatta ttccacagat taaaattaat
    26881 ctattatttt ttgtattttg tggaatatta taaaatattc tagtatcatt aaatgccctt
    26941 ttttatttcc acaacatctt ctattttaca gtctagtgct aaacatatct tctccattgt
    27001 atccatagaa acagatttat catttcctag tctgcctaaa acagaaatac ttatacctga
    27061 tatatttaca aattccattt tctttatttt tctgtcaatt aacaatttcc ataatggagc
    27121 gtatgaaatc atgttatcac ctcgcaaaat atattctatc acattttatc tattttggaa
    27181 aatattcatc tatttggtta aataatcacc tgattaagtg tcaaataatt ttatccttct
    27241 aatatgaaaa attaatacta tactaaatga ttggtctata acacatatga tgcattatta
    27301 ttaacatata aaaattttta ttggcgctaa attaaagtaa tatactatta ttatatttgc
    27361 agatatataa gaaagatttt attatatatt taaagtactt gattataata agagacaagg
    27421 gctatgatgg atactataga aagttagaac tatactattt tagaatgaac aattaaaata
    27481 attaaaatta gtttaatctt ttattcttga taaaataata ttaaataaat gcaaaaagaa
    27541 tcttattatt agaaataatg aaaaattata atatatatag acttgtgtaa atatattatt
    27601 acctagtatt aataaaattt tcccattata atagtatttc ttcattatag aaaaatgcta
    27661 ttgataatgt tttgtacact aatgttaaca gttatacata acaaaaatac tgcaagtaaa
    27721 tcctttttac aaaaatctac ttgcagtctc tatcataaat tatatcccaa ttttactact
    27781 ctttaataag ctattatttt ttacaaatat agtaattaga tttataatat catattttca
    27841 caattactat tattccctaa tatctcttct tcaaatgtat tagaattcat caactttatt
    27901 atacatacaa aatcattatc tttatctata atattttcta aatcacgttt taagctcata
    27961 atcttagatg gagttatttc acctctaaaa actgattttt gaaaatgcga gagatatttt
    28021 ttacacactt taaaaacttt acttactctt ttttctccta catcatagac tacaaataca
    28081 taattataat ttaaattgtt tttctttttc atatgtaata tactatttaa actgaaaaat
    28141 agacaaaacc ttggcaaatt ataatagaat aat
//
LOCUS       DBGJFK010000048        27042 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.048, whole genome shotgun sequence.
ACCESSION   DBGJFK010000048 DBGJFK010000000
VERSION     DBGJFK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27042
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.048"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..288)
                     /locus_tag="ACOIAP_002394"
     CDS             complement(<1..288)
                     /locus_tag="ACOIAP_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGZ2639276.1"
                     /translation="MNSNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLDLSIANPKIISFMIVLLVAYKFKSIGISIITG"
     gene            complement(281..982)
                     /locus_tag="ACOIAP_002395"
     CDS             complement(281..982)
                     /locus_tag="ACOIAP_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGZ2639277.1"
                     /translation="MERTQQLRESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEDSYE"
     gene            complement(1260..2645)
                     /locus_tag="ACOIAP_002396"
     CDS             complement(1260..2645)
                     /locus_tag="ACOIAP_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGZ2639278.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIVKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTADSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGVQLIPIK
                     QEHNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYRESLSDALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPEGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESIEELKAGL
                     SILKRLLEEKK"
     gene            complement(2749..3987)
                     /locus_tag="ACOIAP_002397"
     CDS             complement(2749..3987)
                     /locus_tag="ACOIAP_002397"
                     /inference="COORDINATES: protein motif:HMM:NF017390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HGZ2639279.1"
                     /translation="MELFIQVIKFNIYISPLILFFILFTKKISKYTFKFNYFICLLII
                     VRMLFISKINLNILNINNSTINIYKHNINNYIPYSQDIILDIFMYIWILGIILISFHY
                     LRTNLKFYNYVENFKKEILEIDITSILDEQVKELNINKKLKIYKVKGVYSPAIIGLTC
                     CEIIIPEKKYNNKELRFIFKHELIHYKRKDNLFKLLISIICIIHWFNPILYLLKKYFN
                     ELCELSCDEIVIDKCSISEIKEYAYIILDTIKYQKTLKYSSFVSQFLNKKNITLKKRL
                     NYMFNQDKKKINLGFKLLLTFIIIGSIFTINSNFKQNEDIEDTTGKINYNKNGETYGT
                     DIIDSNGNSIEPELIQAIGRGKKVGYVKKRDLYDCDNQPNTPEEAVLYTRKRNFNIFK
                     ITIPLYDKEGVKIIGRFEIN"
     gene            complement(4000..4377)
                     /locus_tag="ACOIAP_002398"
     CDS             complement(4000..4377)
                     /locus_tag="ACOIAP_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2639280.1"
                     /translation="MIILKKIPKSELLVMNFIWDKGIDKIPAREVANYMENSHGWTKG
                     TTGKVLSRLSDKGFLEFEKDGRNTIYTIKVKHEEYLKFETKDFLELIHKNSIHSFISS
                     LGCENEMSDDDIKELEQWLKKMK"
     gene            complement(4871..5293)
                     /locus_tag="ACOIAP_002399"
     CDS             complement(4871..5293)
                     /locus_tag="ACOIAP_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HGZ2639281.1"
                     /translation="MNTFKIEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESIITRYELIHIDLENTKLIFTENMSERNVF
                     GKINSVLVRILFGKRQPEEFNKFIKNLEMELENNSVNL"
     gene            5770..8673
                     /locus_tag="ACOIAP_002400"
     CDS             5770..8673
                     /locus_tag="ACOIAP_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2639282.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISTILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     EVVEETEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIVGESGVGKSLFS
                     RHMYEFAKQKKIIKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDAPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     VEYTEIRKYLKNAIFIPFNLEEALVKGNLLSDKYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSSEDIFSMSDLNSFVNDSLVKLVKELMNDIVEKNI
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEAKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNINTKTID
                     RVDLLMALEAARKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENIKETSNILAIVGTINPKVPGINFI
                     PYNKEVFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGFIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDEEFMNNANKCFNKDAFKKIIFDKFKHL"
     gene            8706..9152
                     /locus_tag="ACOIAP_002401"
     CDS             8706..9152
                     /locus_tag="ACOIAP_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2639283.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKDTYINAVLERE
                     KTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLNVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNVKLLKNIKNASTKEEVAKLLDFIEI"
     gene            9273..9575
                     /locus_tag="ACOIAP_002402"
     CDS             9273..9575
                     /locus_tag="ACOIAP_002402"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639284.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            9754..11160
                     /locus_tag="ACOIAP_002403"
     CDS             9754..11160
                     /locus_tag="ACOIAP_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HGZ2639285.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRITTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGIAVGIYFALWALFRKNKASIL
                     DYLEKQALKNVEEEPVAV"
     gene            11505..12563
                     /locus_tag="ACOIAP_002404"
     CDS             11505..12563
                     /locus_tag="ACOIAP_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGZ2639286.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGECDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEKHVLKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIKAGDSVVVLGCGPIGQFSIQWARVFGASKVIAVDIFDEKLELSKFLGANYILNS
                     KEVNVIKEIKTITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATERILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            12660..13346
                     /gene="araD"
                     /locus_tag="ACOIAP_002405"
     CDS             12660..13346
                     /gene="araD"
                     /locus_tag="ACOIAP_002405"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0019568 - arabinose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGZ2639287.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNVVDGKLRPSSDTPTHLVLYREFEELGGIVHTHSSWATI
                     WAQIGKPIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNLMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            13364..14011
                     /locus_tag="ACOIAP_002406"
     CDS             13364..14011
                     /locus_tag="ACOIAP_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HGZ2639288.1"
                     /translation="MLESLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKNTGYILITPS
                     GIGREELKVEHICVLDLDGNVIEFEKGIKPSSEVLMHIEIYKTRENVNAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKIVSKLLLDTDACLLERHGL
                     TTVGNDLAEALLKSRYVEDVAEIYYKSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(14184..15551)
                     /locus_tag="ACOIAP_002407"
     CDS             complement(14184..15551)
                     /locus_tag="ACOIAP_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGZ2639289.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILVSFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(15741..15829)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            16256..18376
                     /locus_tag="ACOIAP_002408"
     CDS             16256..18376
                     /locus_tag="ACOIAP_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGZ2639290.1"
                     /translation="MGKVLVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVVTWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKEGFAKLKSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSRICNKLLKSNITANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKVTSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPIDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQKKNQETFNNPFAEALAKLKNK"
     gene            18477..19730
                     /locus_tag="ACOIAP_002409"
     CDS             18477..19730
                     /locus_tag="ACOIAP_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HGZ2639291.1"
                     /translation="MDLSSIFKHYCKECENTWNNSSVELFDNIETYSKDSQKKMEKEL
                     DKLINTISVHLERYPSDIVLRKMWVKKGEIFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDSDLPISDIMQAMRNVWISNALQVLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTSIDKNDKILFNNWLEKRLLGEHIKSNDYHESKVSQMIDYIESVYPREKFIEV
                     YESLLLIFKSQVKSLKQHGEENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEID
                     FCIGYGFLLQISDDLQDVKEDLKYNHKTIITEMAKEGNLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVERFIPYTIDYSLEIEEKMK
                     EKFKSIDVLNNENEYKEMIDIICAE"
     gene            complement(19885..20946)
                     /gene="ytvI"
                     /locus_tag="ACOIAP_002410"
     CDS             complement(19885..20946)
                     /gene="ytvI"
                     /locus_tag="ACOIAP_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HGZ2639292.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIKLITNNTNLNRTLISIVILLAFYGLCIFLLISFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALMLGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            21220..21960
                     /locus_tag="ACOIAP_002411"
     CDS             21220..21960
                     /locus_tag="ACOIAP_002411"
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HGZ2639293.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKDLN
                     IKYIFDYRSDQEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIDYKPKFKGIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YTSVEAYLYGEFNLNKEEIKKLRNQYLE"
     gene            21972..23750
                     /locus_tag="ACOIAP_002412"
     CDS             21972..23750
                     /locus_tag="ACOIAP_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2639294.1"
                     /translation="MSLNITARQVNIIKILLNSKDTISGLALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFEEINLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIREKKLLIKKLLLDILNENGLVLTDIEFKNVLNNILVMLS
                     RHKYNEKEFIENYVENYRRKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSDKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKVFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYELIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            23917..24834
                     /gene="pfkB"
                     /locus_tag="ACOIAP_002413"
     CDS             23917..24834
                     /gene="pfkB"
                     /locus_tag="ACOIAP_002413"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGZ2639295.1"
                     /translation="MIYTVTLNPSIDYIVKLNELKTGSTNRVNEEYVYPGGKGINVSR
                     ILKELGNDNISLGFISGFTGEYIIRTLEEKNLKTDFIKIKNGFSRINVKIKESEETEI
                     NGQGPNIDDEDIDILYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            24871..26790
                     /locus_tag="ACOIAP_002414"
     CDS             24871..26790
                     /locus_tag="ACOIAP_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGZ2639296.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAIFAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSNSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIATKDNNTNKYPQVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YAINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT        10572 a         3069 c         4381 g         9020 t
ORIGIN      
        1 tcctgtaata atagaaatac caatagattt aaacttatat gcgacaagaa gtacaatcat
       61 aaaagatata attttagggt tagctataga taaatctagg ctatctccat taaaaaatac
      121 atctttagca gttaatgaag taagtattgc tacaggtata aatttcatga tttttttcaa
      181 aaaatcaggc atctcttttt ttgagaaaat taacatagga agcactcttg gtagatatgt
      241 aacaatgtac attccaatta taataaaaaa tatataatta ctattcataa gagtcctcct
      301 ttttacagta agattcttct ataaagaaac caattaaaga tgctaaaatt gatgcaacta
      361 ttattactaa attgcttttg aataatgcat ataagataac cgaaataatg attgatgata
      421 taaataccac aatataaatc ttatttttta tttgagaaac tattaaagct ataaacatag
      481 aagtcaatat aaagccagaa atagaactgt ctatagatat actttctcct aaaaatgctc
      541 caataaaatt agctaaaact gatgaaatta agcagaagaa attgagataa atagcatttc
      601 tatcagacca atttccagca gtaaattttt cataattaac tgcaaaagtt tcgtctgtta
      661 tagtatgaca aaatggcaat ataaattttg gacttttatt ttttatgtac atgttcaaat
      721 tagaactcat tagaaaatgt cttaagttaa ctataaatgt agtcaaaaca atagatgtta
      781 cacttgcacc agtagaaatc attgaagctg caatgaattg agagcttcct ccaaatacta
      841 aagttaccat tagtgctatt tgaaaaggtg aaagaccaga tttttgtaat agtattcctc
      901 ctactatacc tataggtata taacctaaga atataggaat tgaagcaata aagctttctc
      961 ttaactgctg agttctttcc acaataaatc actccttttg tattaaatgt attaaagtat
     1021 ttgtaaaaca taaaaataga ttaattttat aattgcaatt ataattaaaa ataaatttga
     1081 attaatatat aaattactgt ataacaaata gacagtctta aactattatt aaattttatc
     1141 tatttgttac tattatgtaa caatacatat taatctctat aaattaatta ctatctgttg
     1201 taattttatt ttaacaacaa aaaaaaatac acacaattaa aatattgtgt gcaatacaat
     1261 tatttttttt cttctaatag tctttttaat atgctcagac cagctttaag ctcttctata
     1321 ctttctgtag cacatacagc tattcttatt gcagaaattg gtttttcttt tccaacagca
     1381 aaacgttcag aagcataaac ctgtacacct tctttaagtg cttgtatttc aaatttttct
     1441 gccattattc cctcaggaag aatcaaccat ctaaatatac attcttcatt tcccaaaaga
     1501 ttatacccag ataaatattg attaataatc ttgtttcttc ttcttgcaga tttacgacgt
     1561 gcattaatta atttatcagc ttcacctgat gtaatcatac gataagcaat ttctgttaaa
     1621 aaataagatt gagataaatt aatgttgtat aatgcgtctg ataatgattc tcgatactgt
     1681 ttaggtgtag agatatatgc tagccgtaaa ctaggtgcaa taatttttga taaactcgta
     1741 atataaattg tttggttagg aagataggaa gctactggat ttaaatgtgt ttcattaagt
     1801 aaactatgaa tagcatcctc aataacaatt aaattgtatt tagatgcaat atttgcaatc
     1861 atttttcgtc cattttgtga cattatatgt gtagttggat tttgataatc tggtattatg
     1921 tatagacctt taatattttc atttttacaa gcatacaata gtccttcttc actaatttca
     1981 ttatgttctt gcttaattgg aattagttgt actccaagca ttttagctgc tgtctttatt
     2041 cctggataag ttaatgggtc tacacctatt ctatctccat gttgaaataa acctgccaaa
     2101 atagcaacaa ttgcattttg tccaccactt gcaggaagta agctatctgc tgtagtttca
     2161 agcccagctt tataaattaa tttggcaata gcttcttttt gccatttagc gccatctctt
     2221 tgtccatatt ggaatatagt tttaaaatcg atttctttaa ctatgtgttt aaataaagta
     2281 ttcatttctt ctagtgtaaa atctgggttc attgtaccca tttcaataaa tgtaatttta
     2341 ttattactgg acattaagaa taggtttgaa cgtgtatcat aagatacaaa agttccactt
     2401 cctgtaactc cacttatgag accttttttt tcacaaattt taaaagctct agagatagta
     2461 ctcacattta catctaggaa atctgccaat tcacgttggg gtggcaattt agtacctggc
     2521 aataaaaacc cattgttgat atcttgttct agttgttctg caagggcctt atataatatc
     2581 tgaccttttg aaggtctctt tggcttccag ttcataggat aattttcaaa agaattaatt
     2641 ggcataagtt ttcacctcac gttattagtt taattttttt ctttatctaa aacaataaat
     2701 tctaaggata caaataaaaa ctgataggta ataattctat cagttctttt aattgatttc
     2761 aaatcttcct ataattttta caccttcttt gtcgtaaaga ggaattgtta ttttaaatat
     2821 attaaaattt ctttttcttg tgtataaaac agcttcttct ggtgtatttg gttgattatc
     2881 acaatcgtac aaatctcttt tttttacata gcctactttt ttacctctac ctattgcttg
     2941 tataagttct ggttcaattg aatttccatt tgagtctatt atatcagtac cataggtttc
     3001 tccattttta ttataattaa ttttaccagt agtatcttct atatcttcgt tttgtttaaa
     3061 attagagtta atagtaaata ttgaccctat tattataaag gttaacaaaa gcttaaaacc
     3121 taaattaatt ttctttttat cttggttaaa catataattc aacctctttt ttaaagtaat
     3181 atttttttta tttagaaatt gagatacaaa tgatgaatac ttcaaagttt tttgatactt
     3241 tattgtatct aatattatat atgcatactc tttaatttca ctaatgctac atttgtcaat
     3301 cacaatttca tcacaagata attcacatag ttcattaaag tattttttta ataagtataa
     3361 aattggattg aaccaatgta ttatacatat tatactaatt agaagtttaa ataagttatc
     3421 ttttctttta taatgaatta attcatgttt aaagataaat cttaactctt tattattgta
     3481 ctttttttct ggaattatta tttcacagca ggttaaacct ataatggcag gggaataaac
     3541 acctttaacc ttatatattt tgagtttttt atttatattt agttctttta cttgttcatc
     3601 taagatacta gtaatatcta tttctaaaat ttctttttta aaattttcta cgtaattgta
     3661 aaatttaagg tttgttctta aatagtgaaa agagattaat ataattccta atatccagat
     3721 gtacataaat atatctaaaa taatatcctg actatatggt atataattat tgatattatg
     3781 tttatagata ttaatagtgc tattattgat atttaatatg tttaaattta tttttgatat
     3841 aaatagcatt ctgactatta ttaaaagaca tataaaataa ttaaacttaa aagtatattt
     3901 gcttatcttt ttagtaaata aaatgaaaaa aagaattagt ggacttatgt aaatattaaa
     3961 tttaataacc tgtataaata attccataaa atatgtctcc tatttcattt tttttagcca
     4021 ttgttcaagt tcttttatgt catcatctga catttcattt tcacaaccta atgatgatat
     4081 aaagctgtga atagaatttt tatgtataag ctctaaaaaa tccttcgttt caaattttaa
     4141 atattcctca tgtttaactt taatagtata tatagtattt ctaccatctt tttcaaattc
     4201 taaaaaacct ttatcactta atctagaaag tactttacca gtagtgcctt ttgtccatcc
     4261 atgagaattt tccatgtaat tagcaacttc tctagctggt attttatcta tgcctttatc
     4321 ccatatgaaa ttcataacta acaactcaga tttgggtatt tttttcaata taatcactcc
     4381 ctttaacttg attatattag acaaatgtct aacagtcaat ataatatatc atcatttata
     4441 aagaatatct atattatttt atacttaaga actaaatatt atatatttat agataaaaaa
     4501 gatattaaga gttttatgga atagaataat ctacttccta ctagatataa gaatataaca
     4561 tatatttttt agtgaataaa ttaatatctg ttctaagtta gaataggata atcttattag
     4621 ataaagatta tcctatttat tggaagttta agatgtattg gagattatta atttttttct
     4681 ttttttaact aaaagcaata atacataaaa ttattattac taatgaaact cctaatgtgg
     4741 tatatagtca tggtgttata tgactatcaa tagtttttta agtaattatt gtaacaaata
     4801 gcagtatccc aaaaatactt aaaaatatgt ttctagacag tttttaaata taatataatg
     4861 taacttatat ctataaatta acactattat tttccaactc catttctagg ttttttataa
     4921 atttattaaa ttcttctggt tgcctttttc caaacaatat tcttacaaga actgaattga
     4981 tttttccaaa tacatttctc tcgctcatat tttcagtaaa aataagtttt gtattttcta
     5041 aatcaatatg tatcaattca tacctagtaa taatactttc tcttttattg cttgttttta
     5101 tctcatatac tctatttttt tcgaaattag ttatttcaac cttaaatctt ttattatttt
     5161 tttgttgtac aaatgtgccc actgcttttt tctcattaaa attaggaaaa tttagtcttg
     5221 cagattttgt aaatatatta aatatgtctt ttgcagaata ttttaataaa acttcaattt
     5281 taaatgtatt catatcgttt ttcctcctgt atataaattt aattttataa gttaattttt
     5341 aagttaaaat agtataatat gcaatataaa atcatgttaa aactatttat atagctaaaa
     5401 tcttatatag ataagtatgt atactattat ataaaaataa aattttaaaa cagaaagagt
     5461 taaaaacata gtttattgta atttttattg ttgagtagat acgtactatt atatatgatt
     5521 gagtaagttt ttcaataata tatttataaa gtattttgca ttgcaattta aacaaagaat
     5581 taaactattt aagattatga atgactaata catttagtaa attactaaat atacaaaatg
     5641 taattgctta tcaaaatgta taaatactta tggcatctag ttacttacag ggtttgagta
     5701 gaaaaaaata tcaaagtaag tatggcatga tagttgctta tatatttaac aagaaaggag
     5761 ttattaagca tggagttgag agataaactt gtaaacatca taaatacaga aaataaaaaa
     5821 gatccattaa cagatgttca aatagcaaag tttttaagta caactagaga gaatataact
     5881 aatttgagaa aagaacttaa tataagtaat tcaaggcaaa gaagatatcc ttatctaaaa
     5941 tcagcaattt cgacaatatt acaaaagaat aagaatattt ctatatcaga aattacaaga
     6001 gaattgatga cagaaggttt taatatatct agaagagttg tagaggaact tttacctaaa
     6061 gaaagtttag aaatggaggt agtagaggaa actgaagaag aatcgaatga cccatttgaa
     6121 actctgatag gtaataaagg gagtcttaga aatgctgtag aacaggctaa atctgctata
     6181 ttgtacccac ctaaagggtt accgacgttg attgttggag aaagtggagt tggcaagagt
     6241 ttattttcta gacatatgta tgagtttgca aagcaaaaaa agataataaa agaaagttcc
     6301 aattttgttg tatttaattg tgctgactat agtgataatc cacaattatt attgtcttta
     6361 ttatttggat ataaaaaagg tgcatttaca ggagctgaat atgatgcacc aggtcttgta
     6421 gaagaagctg atgagggagt tttatttttg gatgaaatac atagattgcc tccaaaaggt
     6481 caagaaatac tattttccat cttagatagg ggaaagttta ggagattagg tgaaactaat
     6541 gctgaaagaa aagtaagtat tatgttgatt ggggcaacta ctgagaatgt agagactaac
     6601 ttattattaa cattcagaag aagaatacca atgctaataa ctttgccacc attacatgat
     6661 agattactaa aagagaaaat agaccttata tataatatct ttcaacaaga gtgtaataga
     6721 ataaacgcaa aaatatttgt agataaaaat gtgattgaaa tacttgcact aaaaaagttt
     6781 agtggaaata taggacaatt acaaaatatg attcaggttc tttgtgcaag agcttttatg
     6841 aagtttataa attctaaaga tgaagatagt gaatcgatag tggtagtaga tataaatgaa
     6901 gttttaaagc ttaaagattc ttttaaagat gctgcctttc aagaggttga atatacagag
     6961 ataagaaaat acttgaaaaa tgctatattt ataccattta acttagaaga agcattagta
     7021 aaaggaaatc ttttaagtga taaatatata ttaccagagg acatatacaa aacaattgaa
     7081 aagaaatatt atgacctaaa atccctagat attgaagata tagatataga gaatatttta
     7141 tggactttta ttttaaatag atttgctgac ttaaagttta atctcgatag tagtgaagat
     7201 attttttcaa tgagtgattt aaatagtttt gtaaatgata gtttagtcaa actggtaaaa
     7261 gaacttatga atgatatagt tgaaaaaaat attaatttag aagtaaataa aaatatgttc
     7321 aaatatctag caatacactt agaagaagct ataaaaagaa ttaagctaaa tcaaaagata
     7381 ataaacgtaa atttagaaaa aataaagatt gatttttcaa aagaatatga aattagtaaa
     7441 agttttgcaa taaaaattga ggaatcaata ggtattaaga ttccagatga tgaaattgga
     7501 tttataacgc tctacataaa gtctgcacta aaaaatgaag cgaaaaaaga caaagtgggg
     7561 ttaataataa tttctcatgg acgtatagct acagagactg taaatgtagt taaagaactt
     7621 ttaggtgtaa agtttcctgt ggctatagat atgcctttag atgaaaaacc aataaatata
     7681 tacaataagg cagtagaatt gtcaaaaata atagaccaag gaaaaggaat attgtttttg
     7741 gtagatattg gctcacttac aaacataggg caaatagtaa ataagagaac caatataaat
     7801 actaaaacta ttgatagagt agacctctta atggcactag aagcagctag aaaagtttct
     7861 atgggagagg aagaacttga tgaaatattt ttttctttac taaaagatag gatgggatat
     7921 aactatgaat tagaaaagca catagataaa tcaaatgcaa ttgtaacatt atgtcttact
     7981 ggagaaggaa ctgctaaata tataagtaaa acattggaag aaaagtatga taacactaaa
     8041 tgctatcaaa tgagtgcatt ggatgaaaat ctattttgta aaattgaaaa tataaaggag
     8101 acaagcaata tattggctat tgttgggaca ataaatccta aggtaccagg tataaatttt
     8161 ataccctaca ataaagaagt tttcaaaaat ttggatatat atctatcaaa atcaaaacaa
     8221 caagatgaca gaccaattaa atcgtatgaa agaatgcttg atgaggattt agtgattttt
     8281 gaaccagata tatattttaa aaaggattta ttagaatatg tatgttcaat tcttataaat
     8341 aaagaatatg tagaaaaaga ttatttagat tctgttttac atagagagga gatgcttcca
     8401 acatattcta aaggatttat aggtgtgcct catggagatt cttctactgt aaatagtacc
     8461 aggtttgttt ttgtcaaact aaagaaccct attgattggg gtgtaggcaa tgtaaatttc
     8521 atatttatgc cagtttttca ggctaatgat aaagagattg ttaagaatgt tcttgagata
     8581 ctaaaagatg aagaatttat gaacaatgcc aataagtgct ttaataaaga tgcttttaaa
     8641 aagattatat ttgataaatt taaacatctg tagccatagc aaaaaaattg agaggagtca
     8701 gagtaatgaa tgtagattta atatcattag gtttagaatc taatgattat gaaagtgtta
     8761 ttgaagaatt aggaagtata atgtgtaaaa aagaatatgt aaaagacaca tacataaatg
     8821 ctgtcttgga aagagaaaag acattaccaa caggtctcga tattggagaa atgtgtgttg
     8881 ctattccaca tacagattca aagcatgtaa atgaatctaa tgtagctgta gggatattga
     8941 aaaatcctgt aaaatttaat tcaatgatag acccaaaaga taggcttaat gtagaacttg
     9001 tatttttatt ggcagtaaag aacccagatt cacaagtaaa actgttaaaa gatttaatgt
     9061 cagtttttca aaatgtaaag ttattaaaaa atataaaaaa cgcatcaaca aaggaagaag
     9121 tagctaaatt attggacttt atagaaatat aatgtatgag aattttataa ataaaaaatt
     9181 aaaatttaaa caatcaaagt aagtgttatt ttttaatagg tttaatatat ataaaataaa
     9241 aatttagagt gaaaaattag gaggaaatta ttatgaaaca atttaatgta ttatcagttt
     9301 gtggttcagg gacagttaca tcatctatgg tagcaggtaa attaaaagaa gtattaggga
     9361 ataagggaat ttctattact acaacagaag ctagaccaac agaagcacta aatttagcgc
     9421 aatcaggaag atttgatttt ataacattta ctagtccact tcaaacaggc gattatggaa
     9481 taccaactat aaatgcattt gcttgcctaa ctggtatagg ggaagaggca ttctttgaag
     9541 aagttttgac tgttattgaa gggatagata agtaagtttt ggagatgtga atttatagta
     9601 tttaaatcaa tgatttagat actataataa gctaatatta actaaatatt tgtaaaaaaa
     9661 cattttatat gttgtcataa attaaaaaat tataaaaata gtcatttaga tattaaacta
     9721 agcttataaa tatttataaa taggaggaaa aagatgttag aatttatgaa atctataatc
     9781 gatacatttg gttctgcaat tatagttcca attataatat tcataatagc aaagatattt
     9841 aaagtaacta ctaagaaatc gtttctttct gctgtgtacg caggagttgc tttacaaggt
     9901 tttacattga ttttaaattc atttacacca ataataacac cagttatcaa caggatggtt
     9961 gagagtacag gagtaaattt accagttttt gatgttggct ggcaagcaac atcattggtt
    10021 gcattttcaa caagtgcagg tatgatatat ttgggtcttg ggatattatt acaaacaatt
    10081 ttatttttga taaaatggac agacgtgttt caaccatcgg atttatggaa taactattct
    10141 tacatggtat ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca
    10201 tgtatggttt tattaaactt atatagtttg ttaatatcag agttagttgc aaagagatgg
    10261 tctagttact atagatatcc taattgtacg ataatagcta tgcataatgt tgaggcttct
    10321 gtgtttgcag tatttgcaga ccctatatat aataaattgg gattaaataa aataaaatta
    10381 aatccaaaag aattagagaa gaaattagga ttcttaggtg aaccaattac tttaggtctt
    10441 tttttaggta tgtttatagg tatattaggt aatatgacaa gaataactac tatggaagct
    10501 tggggagaaa taatgaaagt aggtatatct acaagtgcag ttatggcaat attcccaaaa
    10561 gtagcaagca tgtttgctca agcatttgca cctataacag aagcagctag aaagattatg
    10621 caaaaagctg gaaaccgtga gtggtacata gcagtaaatg atgctgttgg gtatggtgaa
    10681 cctgcaactt taatatcagg tcttatatta attccaataa tgcttgtaat agctatggta
    10741 cttcctggca ataaagtatt accagttgtg gatttattag caattccata tatggttcaa
    10801 ggtttagttg ccatacataa tggtaatata ccaaaagtac tagtttcagg tataatttgg
    10861 tttggattag gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca
    10921 aatataggtg tagctatacc tgcaggagca atgttaataa caagttttaa tatactagga
    10981 aaacctttga tgggattagt tttctttgca tttctaagtg caaatccaat ttatataggt
    11041 attgcagttg gaatttactt tgctttatgg gcattattta gaaagaacaa agcaagtatt
    11101 cttgattatc tagaaaaaca agcacttaaa aatgtagaag aagaacctgt agcagtttaa
    11161 gtttataaaa atgaaatagg aataattaaa ggagtttata attgatttta tataagtatc
    11221 agatagtacc tgagaaatat ttaaatgaag tatagacttc tttttattta ggtaatattt
    11281 gtaattgtaa agcattgtat ttttatagtt gagttttctg tataacctgt catttaaaac
    11341 atactctttt atatttatac agtaatgtaa tttgatttta taaaatgtaa ttcctattgg
    11401 caaaagactt tgtatataag gtatttacct gaataaacca tttatctttt gtatggcata
    11461 gatattgcta tatagaaata tatagcatga aaggagatat ttatatggga aataaaatga
    11521 gagcatcagt attgtataat gtaggtgatg ttagatatga aatggtagat ataccagaaa
    11581 taacagatac acaagtgctt gtaaatgtaa aatatgttgg aatatgtggt tcagatttac
    11641 ctaggtctat ggtaagtggt ttgagtggaa atacaaaata tccattgatt ttaggacatg
    11701 aattttctgg tgaagttgtc aaaattggag aaaaagtaaa gcatattaat gtaggagata
    11761 gagtagccgt tgcaccatta gtaccttgtg gagaatgtga ttattgtaat gaaggtaatt
    11821 ttggcttgtg tgatgattac aatataattg gaacaagagt aaatggagca tttgcagagt
    11881 atgtaagagt tccagaaaaa catgtcttga aactaccaga tacactggat tatgaaactg
    11941 ctgctggaat tgaaccagca actatagctt atcatgggat ttcaaagtct aatattaaag
    12001 ctggagatag tgtggttgta ttaggatgtg gtccaatagg tcagttttct atacaatggg
    12061 caagggtatt tggtgcatct aaggtcatag cagttgatat ttttgatgaa aagttagaac
    12121 tttctaaatt tctaggagca aactatatac tgaactcaaa agaagtaaat gtaattaaag
    12181 aaataaaaac aataacaaat ggtggtgctg atgttgtaat agagactgct ggtagccgat
    12241 ttacacaaga acaatctcta tttgtagcaa aaaagagagg aaatatagta tttgtgggta
    12301 tatcacacac agaattacca cttagtgcag acgctactga gcgtatatta cgtggtgaac
    12361 ttactttgaa aggctcttgg aattcatata caagccctta tcctggaaga gcatggactg
    12421 caacattgga ttttatggga aaaggagata ttatttttaa acctatgatt tcacataaaa
    12481 taggtcttaa tgaggttggt gactttttaa gtaaaatgag caagagagag attaatttca
    12541 ataaaatcct agtagaaata taaaaattta ataaaaattc taaaacaatt aaatttcata
    12601 attatgacat taaacaaaat agaaataatt ttttaaaata aaatatagga ggaagaaaag
    12661 tgttagaaaa tttaaaagaa gaagtattaa aagcaaattt agaactacct aaaaaaaagc
    12721 taattactta tacttgggga aatgtaagtg gcatagatag agaaaaagga ttggtagtga
    12781 taaaaccaag tggtgtagag tatagtaata tgactgtaga agatatggtt gtagttgatt
    12841 tagagggaaa tgtagttgat ggcaaactaa gaccttcttc agatactcca actcatctag
    12901 ttttatatag agagtttgaa gaattgggag gaatagtaca tacgcattca agttgggcaa
    12961 caatttgggc tcaaatagga aaacctatac catcttgtgg tactactcat gcagattatt
    13021 tttatggaag tataccatgt accagaaaaa tgactagaga agaaatttgc aatgaatatg
    13081 aaaaggaaac tggaaatgta attattgaag aatttatggg aagaaatcca attcattgtc
    13141 caggaataat tgtaaatgac cacggacctt ttacatgggg aaaagatgca aatgaggctg
    13201 tacacaatgc agtagtttta gaagaagtcg caaagatggc ttattataca gagctaatga
    13261 gtcctgataa tcttatggat aaggttctta tgaataagca tttttcaaga aaacatggaa
    13321 aaaatgcata ttatggtcaa aaatgattgt ctggaggtaa gttatgctag agtctttaaa
    13381 aggtaaagtt gtggaaatag caattaaagc agagcattat ggtttatgta aagaaaagac
    13441 tggtaatttt agtattagag ataagaatac tggatatata cttataactc catcaggtat
    13501 aggaagagaa gaattaaaag ttgaacatat ttgtgtattg gatttggatg gaaatgtaat
    13561 agaatttgag aaaggtatta agccaagcag tgaggtattg atgcatattg aaatatataa
    13621 aacaagggaa aatgtaaatg ctatatcgca tactcattct ttatatgcaa cagcattttc
    13681 agtggcaaag aaaccaatta taccaattgt atatgaatca gttaattatg gcggttatgt
    13741 agatattgct ccatacgaaa gaccaggaac tttaaaatta gctaagatcg tttcaaaatt
    13801 actgttagat acagatgcat gcttattaga aagacatggg ttgacaactg taggtaatga
    13861 tttagccgaa gcattattaa aatcaagata tgtggaagat gtagcagaaa tatactataa
    13921 gtctttagta ttaaatcaat ttaaagaact tgaagtagta gatgttgatg agtttaaatc
    13981 ttggaaatac ccagaagaaa taaagtttta atctaagtaa tttttattga agtggttaat
    14041 taaaatatat gtattattta tatcaattac tatattgtat tatgttaatt atcgtctttt
    14101 gtaaatatat ttattacatt ttttcaaaaa aatatagaat ccgaaagcca tataaaattg
    14161 acttgggatt ctatattttt tatttatgca tttttcttta tctgattttc tggtgaattt
    14221 atatgttcaa aatatttttt agtttcagat actattatag gtgataatgc aagtaaagct
    14281 atcaagttag gtattgccat aagtccattt acgatatcag caattatcca aacaacttct
    14341 aactttaaga atgcacctaa taacaccata gccacaaata cagttctata cccattcata
    14401 ccttttacac caaacagaaa ttcaaaacat ctttctccat aataactcca tcctaaaatt
    14461 gtagtaaatg caaataatgt taaactaact gtaagtaata ttggtccaaa tgtaggaata
    14521 gccccgttaa aagctgcttg tgtcataaca gctccattta ggtctgaaca ccatacccct
    14581 gaaataacaa gagagaatcc agtaagagta cagattataa tagtatctat aaaagtacct
    14641 gtcatagata taagaccttg ttccgctggc cattcagttt tagcagcagc tgcagctatt
    14701 ggagcactac ctagaccaga ctcatttgaa aatacaccac gagcgatacc atttctaatt
    14761 gctaaggaca tagttgctcc tagaaaacca ccagtagcag cagtaggtgt aaatgcactt
    14821 ttaattatta acataaaagt ttcagggatt ttattccaaa aagatactaa aatgattcca
    14881 cagattacaa cgtatataac tgccataaaa ggtactattt tagtagctac gttagatata
    14941 cttttaagac ctccaaatac aaccaaagct acaaatactg ctaatacaac ccctgtaatt
    15001 ctagggtcta taccaaaact attatttatt gcgtctgtta ttgaatttac ttgagtaaaa
    15061 gtacctattc ctaaaagtgc aactagtata ccacttatag cgaaaaatat tgcaagaggt
    15121 ctccattttt ctcccatacc atttactatg taatacattg gtccaccaga cacttgacca
    15181 tttttatctt tagttctgta ttttattgca agaacacctt ctgaatactt agtagccatt
    15241 ccaaagaatg ctgctatcca catccaaaaa agtgcaccag gtccaccagc tttgatagct
    15301 gtagcaacac caacaatatt accagtacca actgtagcag ctaaagcagt acataaggct
    15361 gcaaaacttg aaacatcacc actacctttg ttttcagcag agaatattaa cttaagagct
    15421 cttggtagtt tagttatttg aacaactcca agtttaacag taagtagtat accagtacca
    15481 actaatagta ctagtagggg tggtccccaa ataaaagcat caactttgtt taaaatatca
    15541 attagattca taaaaacact ccctcatttt ttttgcttta cataatcaat agaattttta
    15601 atgaagtaat tgacaggaaa taagtataat ttattaataa tttctagtgt aataaaaaaa
    15661 gctaaatcta aaaaagattc agctctggat gtacactaat tagcaaccaa aataaaagta
    15721 ttagtaaata ctgtttttgg tagataatcc ctgtcctttt gcctgagaga ttgagcataa
    15781 aagccttgcc ccttcggcgc ccataatggg tctctccaga gttccgtaaa ttttacagtc
    15841 ctactttaaa agtacctgag agtgttactc cttcggtgtg ccatatagca actcttctat
    15901 aaaatcttaa ccggatattg atttgtcata gcttattgta ttaataatat taatataagt
    15961 ttttatgttt tgtcaactga aaaattaaaa aacaaagaaa aaagataaaa atgtaagcct
    16021 atttacgaat tataaactta gaaagatgag taatatacgt gaaaataaat tttgtaatag
    16081 acatacaaat taggtgtaaa ataagtttta aataaaaaaa caataaaatc ttaaataatt
    16141 aattagatat gattaaatta tggtaatatt atagttacga tattaagaaa agttctattt
    16201 acttagattt taagcgtaat atgagattat gtatagagaa aggatgtatt tttagatggg
    16261 aaaagtatta gtactagcag aaaaaccttc tgttggaaga gatatagcaa aagttttagg
    16321 gtcaaaaaat gaaaaaaatg gttatataga gggaccaaag tatgtggtaa cttgggcact
    16381 aggtcatttg gttacacttg ctgaccccga aagctatgga gaaagataca aatcgtggag
    16441 tttagaagac ttgccaatac ttcctaagca ccttaagact gttgtgataa aaaagagtgg
    16501 aaagcagttt aatacagtca aatcgcaaat gaatagaaat gatatagatg aaatagttat
    16561 agcaacagat gcaggtcgtg aaggagaact tgtagcaaga tggataatag aaaaatcaca
    16621 ggtaaaaaaa cctataaagc gtctttggat ttcttcaagt acagataaag caataaaaga
    16681 aggctttgca aaattaaaaa gtggaaaaga atatgaaaat ttgtattatt cggcaatagc
    16741 gcgagcagaa gctgattgga ttattggaat aaatgcaacc agagctttga caacaaagta
    16801 taatgcacaa ctttcttgtg gaagagtaca aactcctact cttgcaatgt tacttaaaag
    16861 agaagaggaa ataagaaatt tcaaacccaa ggagtactat ggattggaat taattgctac
    16921 aaaaggcaat tcagatataa aatttatttg gaatgataaa aacaataact cttcaacttt
    16981 tagtaaagaa aagatagaat ctacattaaa aaaagtaaaa ggtgtagaca taaaaatatc
    17041 tgaagtaaac aaatcatata agaaaaaata ttcacctgca ctctatgatt taacagaatt
    17101 acaaagagat gcaaataaaa tgtttggatt ttcagcaaaa gaaactttat ctataatgca
    17161 aaagctatat gagcatcata aagtgcttac ttatcctaga actgattcta gatatttaac
    17221 atcagatatt gttggaacat taaaagatag aataaaagct gtaaatatta gtgattattc
    17281 aaggatttgt aataaattat taaaaagcaa tattacagct aataaatcat ttgttgacaa
    17341 ttcaaaggta acagatcacc atgcaataat accaacagaa cagaaggtat ttatgagtga
    17401 ttttagtgac aaagagcgaa aaatatataa tcttgtagta aaaagatttt tagcagtact
    17461 atctcctcct tttgaatatg agcagacaac tataagtgca actgtagaag gagagatatt
    17521 taaggctaaa ggaaacaaag taataaattt aggttggaaa gaaagttata aagatattga
    17581 agacgaagat gagtatgaaa gtataccaaa tgttttagaa aaagatgtac ttaaggttaa
    17641 gggattaaag gtaacgtcag gaaaaacaaa tccaccacca tatttaaatg agggaacatt
    17701 actgactgct atggaaaaaa acggtctagg gacagttgct acaagagcag atataataga
    17761 aaaattattc aattcatttt taatggaaaa gaaaaataaa gatatatata taacatcaaa
    17821 agggagacaa ttattagatt tagttccaat agacttgaag acaccagaac ttacagcttc
    17881 atgggaaaag aaattattgg atatttcaaa gggaaaactt agtaaaaata cattcataaa
    17941 tgatatgaaa gattattcaa aagatattgt attagaagta aaaaatagtg ataataaatt
    18001 taaacatgat aacttgacta aaaatagatg tccagagtgt ggtaaattta tgctagaggt
    18061 aaatggtaaa aaaggtaaga tgttgatttg tgaagacaga gagtgtaata ctagaaaaac
    18121 tatatcacaa gtaaccaatt caagatgccc taattgtcat aaaaaattag aacttcgtgg
    18181 agaaggagaa gggagaatct tcacttgtag ttgcggatac agagaaaagc tatcttcttt
    18241 taacaagaga aagcaagaag aaaagcagaa ggcatcaaaa aaagatgtta atcaatattt
    18301 aaaaaatcaa aagaaaaatc aagaaacatt taataatcca tttgcagaag cattagctaa
    18361 gctaaaaaac aaataatttt aaagttatta tacacaatta taactttaac tgtatattag
    18421 ttatatgtac tgatataata tagtgtatag tttaggcatg aaagtagggc tgttaaatgg
    18481 atttaagtag tatatttaaa cactattgta aagagtgtga aaatacatgg aataattcaa
    18541 gtgttgaact atttgataat atagaaacat atagtaaaga ttcacaaaaa aagatggaaa
    18601 aagaattaga taaattgata aatacaatat cagttcattt agagaggtat ccaagtgata
    18661 ttgtattgag aaaaatgtgg gtaaaaaaag gcgagatttt cttacaaaag acattagaaa
    18721 aagaaaatat ttttaagtta gaaaaaatgg atgtagagga tagaaaaaaa tttttagata
    18781 taacaaaaca atttattaga gatgctagaa aatttgatag tgatttacct ataagtgata
    18841 ttatgcaagc tatgaggaat gtatggattt caaatgcatt acaagtatta tttggtaaag
    18901 aagtttatta ttcaaaagct aactttgcat atagtatgtt atatccatat actgataatt
    18961 atttagacaa tacaagtata gataaaaatg ataagatttt atttaataac tggttagaaa
    19021 aaaggctctt gggagaacac attaaatcta atgactatca tgagagcaaa gtatctcaaa
    19081 tgatagatta tattgaaagt gtatacccta gagaaaagtt tatagaagta tatgaatcat
    19141 tattattaat atttaaaagt caagtaaaga gtttaaaaca acatggcgaa gaaaatcatt
    19201 tgtgtaagga agatttatta tccatttcta ttgaaaaagg tggttcatcc gttttagtag
    19261 atggatattt aataagtgga ttgatgacaa aggaagaaat agatttttgt atcggctatg
    19321 gatttttatt acaaatatct gatgatttac aagatgtaaa agaagattta aaatacaacc
    19381 ataaaactat tattacagag atggcaaaag agggtaattt agataaagtt gtaaataaac
    19441 taataaattt tactattgag ttaatagata gttttaaaat taacaataaa aataaatctg
    19501 taataactat gataaagaat gattgcttaa tgttaatttt attttctgta gtttataatg
    19561 ctgaattttt ttctgtagga tatataaaag aagtagagag atttattcca tatacaatag
    19621 actattcatt agagattgaa gaaaaaatga aagaaaaatt taaaagtata gatgttttaa
    19681 ataatgaaaa cgagtataaa gaaatgattg atattatttg tgcagagtag aaaaaaaggg
    19741 agtgtcttag aatagacttt ttagtttata aggcactctt tttgtataaa atcaaatgta
    19801 ttttcatcat tctaacaatt aaaaagaggc ttatctctat ttgagacagc cctttttaat
    19861 ttaaataaaa atgtcaaggt taaactattt aaatgcagta ataatcccat tatcatgtaa
    19921 gttttttatg attgtagctg cgatagggaa tccaaataat ccagctattc caaatagttg
    19981 agctccaaca aacatacaca ttaatgttat taaaggatat aggccaattt ggtgtcccac
    20041 tacctttggt tctaatattt gtctaacaac agttataatt atgtatagta ttaaaagtcc
    20101 tattgctaaa ttaatatttc cattaatgag tgatataatc atccaaggtg tcagaatact
    20161 tcctgtaccc aagactggca aaatatcaac aagtgctatg atgacagata tagtaaatgc
    20221 attttcaact tttaggatag taagtccaat aagtagttct atgaatgtca ctgatagtag
    20281 tattgcgtaa gcttttagta gttttaaaag agcattaata ctgctatttt ttatatttat
    20341 tatcataaat tgactttttt ctggaaattg ttttaagata aagtttacta ttttttgata
    20401 gtcaaaagta aagaaaaaag aagcaattaa agtaataata agttttaaca taaatgcagg
    20461 tgttttactt gcaatactag caatagcatt aagtgcattt gttgaaatag aagctactaa
    20521 agacatcata gattgactta tattatccca accaagcatt aatgctaggt taacattagg
    20581 tgtactagca tctatcttcg aaaataaagt atttagtgtt ggttgtatac ttgatttata
    20641 tatttcggga agtctaaaaa atacatcact tacacttgca aatatcttca caccaaagct
    20701 aattaataag aatatacaca acccataaaa agctaacagt attactatag aaataagtgt
    20761 acgatttaaa tttgtattat ttgtaataag ttttataata ggtcttagga tggatgcaat
    20821 gataaaactt attacaaaag gcattagtaa tggcaataag aattttaata caatatatac
    20881 aatacttgtt attaaaacta catatgtaaa tttaattata aaattctttt gcttttgaat
    20941 gtccataata taaaacctcc agtgtattta atattattct aaatatggtc ttttttacat
    21001 aaaatatact actgtatatt gattataaac tataaatctt atataaagta aataaattat
    21061 gtaaaattta ggttaatttt gtataaagat atacttttat attttacaat tgctaaccaa
    21121 atactagaaa atattttaaa taaagaactt aaaattgtga taaaattaat ttattgatat
    21181 ttaaaaaagt atataatatg gtttttaaga ggtgttaaga tgaaaaattt tagagattta
    21241 ggtggtaaca aaactgagga tggtaggact gtaaagaagg gattgtttta taggtctgca
    21301 aaattatcaa atttaagtga aaatgatata aagattttaa aagatttaaa tattaaatat
    21361 atatttgatt atagaagtga ccaagaagct cgtaaacatc catcaacaat aatatcaaat
    21421 ataaaaaata taagaatacc agcaatgaga gagttagaag aatcaggagg aagttttggt
    21481 tctattgaag atatgattga tggattgttt gaaaaagatg gtgcatttaa tatgttaaat
    21541 aatagctact ataatttgcc tataaataat ccttcatata aaaaactagt agaacttata
    21601 agagactatt ctaatttacc aatattaaat cattgtacag ctggtaagga tagaactggt
    21661 gtagggagcg ctataattct tatgatttta ggggtatcaa gagagaatat aatgaaagat
    21721 tatctaaaaa gtaatgattt tgcagataaa gagatagaaa gatttataga ttataaacct
    21781 aaatttaagg ggattccaaa agaaaattta aaatatatat ttggtgtaaa tgaagagtat
    21841 atgaaaactg catttagaag aatagatgaa gaatacacta gtgtagaagc atatttatat
    21901 ggagaattta atttaaataa agaagaaata aaaaaattaa gaaatcaata tttagagtaa
    21961 aaggtgattt tatgagttta aatataacag caagacaagt aaatataata aaaatattgt
    22021 taaattcaaa agatacaatt agtggtcttg ccttaagtca agagatagga tgttcttcga
    22081 aaactataca aaatgaaata aaggatatta ataaacaact tagaaatggt aaaatcttgt
    22141 caataagagg agttggttat aaactagaag gaagttttga ggagataaat ctaaatagta
    22201 atctctatga tgatgtagat agagtagaat atataattag aaaaatatta accttaagta
    22261 atgaagaaaa aaatactata aaacttgaag atttagccga ttctatgtat gtaagtgttt
    22321 cgacagtaaa aaatgattta aaagaagtaa aaagaatatt ggaaaagtat tcaatatcag
    22381 ttaaatctaa gcataaacaa ggtatatgtg ttttggagag tgaggataag atattaaact
    22441 gtatagttga cttaagcaat aagagagata atcaattgag tttaaatgat tttttaaatg
    22501 atgacataag ggaaaaaaaa ttactaataa aaaaattact attagacata ttaaatgaaa
    22561 atggattggt attaactgat atagaattta aaaacgtgtt aaataatata ttagttatgt
    22621 taagtagaca taagtataat gaaaaagaat ttatagagaa ttatgtagaa aattataggc
    22681 gcaaaagaag ctcaatttta gaaaatgaac aaaacaaaga aattataata aattcaataa
    22741 aaacattttg taaaaattta aaattagcta catcaataga tataagtaat gataaggtat
    22801 ttgaagaatt tttatataag catattagta gtttatgtaa aaaaataaag ctaggtataa
    22861 atcaatctcc tataatggct caagatataa aaataaaata tccatttgct tttgaactag
    22921 ctaatatagc taaaaagaca atagaaaaag atttgaagat agaaattaat gaagatgaag
    22981 ttgcaaacat agctctacat ataggaggag cagttgaaag agcatcttat aataataaag
    23041 ataaggtttt caaaactata atagtctgta cttcaggtat aggtacatca atgttaataa
    23101 aagctaaatt agagaatata tttaaggaaa aattagaaat attaaagatt attccttcat
    23161 acttagttga atatataaaa gttatagatg ttgattttgt aatatctact gttcctattg
    23221 aagtaggaga tgtaccagta ataaatatat ctccgatttt aagtgataaa gaaattagat
    23281 taattgaaaa atatatagaa acaggaaata tatatctaga tttagatata aaaagcctgt
    23341 ttgatagtga attatttttt actgatttgg tgtttaaaag gaaagaagaa gttatagatt
    23401 ttatggcaag taaacttgta caaaagggat atatagatga ggatatgaaa aaatcttact
    23461 ttgagagaga aaaaatagca acaacagaaa tagggaatat ggtaaccata ccacatggtg
    23521 ctattggaaa agtttttgat aataaaatag caattggtat attaaagaaa cctatttctt
    23581 gggaaatatc agatgttcgt ttaataataa tgttagctct tgataaagac aaaatattag
    23641 attatgaatt aatcttttca aaaatatata aaagagtaga ttccatagca aaagttataa
    23701 gtatatgcga aaatagcagt tttgaaaaat ttgtaaattt atttaattag atgggtggta
    23761 ttgtatatac atctgtaaat ttggataata taaaactaaa taaaataaaa acgataaatt
    23821 tctcttttaa ttaagagaaa ttttttgact ttcaaggata ttaatataaa gttaagatat
    23881 aaacataagg taaataaata aaaaagaggt ggcaatatga tttatacagt gacattaaat
    23941 ccatcaatag attatatagt taagctaaat gaactaaaga caggaagtac aaatcgtgta
    24001 aatgaagaat acgtttatcc aggaggaaaa ggtataaatg tatctcgtat acttaaagaa
    24061 cttggaaatg ataatatatc tttaggtttt ataagtggtt ttactggaga atatataata
    24121 agaacattgg aagaaaaaaa tttgaagaca gattttataa agataaaaaa tggtttttca
    24181 agaataaatg taaaaataaa agagtcagag gaaactgaga ttaatggaca aggtccaaat
    24241 atagatgatg aagatattga tattttatac aaaaaacttg ataagctaaa tcaagatgat
    24301 attttaatat tggcaggaag tataccatct actttagatg aaaaactata cgaaaatata
    24361 atggctagat tagaaaaaaa gaatataaaa gttgtagtag atgcaactaa aaatcttctt
    24421 cttaatgttt taaaatataa accttttcta attaagccta ataacgacga attagaagaa
    24481 ctatttggtg ttaaattaaa ttcaattgaa gacatggtaa aatatgctag aaggttaaag
    24541 gaaatggggg ctataaatgt cttggtatca atgggtaaag atggagcatt gttgattaca
    24601 gaggaagatg aagtgcttat aagtgatgtt cctaaaggaa aagtaaaaaa ttctgtagga
    24661 gcaggtgatt caatggtagc aggatttata tctgggtatt tgaatactgg taaatatgat
    24721 tatgccctta aattgggagc agcttcaggt agcgcaactg ccttttcata tgacttagcc
    24781 aaaagagaat acattgataa attggtaaat gaaatatctg taaagcagtt ttaaaatatt
    24841 aaaaaatata tagaaaggta attaatattt atgaaaatta tagatttatt agatgaaaag
    24901 tcaattaagt taaatttaaa ttcaaaaacc aaatcagaag caatagaaga attagtagat
    24961 ttggtcgcaa atagtggaaa tttaaatgat aaagaaaact acaaaaaagc aatttttgct
    25021 cgtgaagaaa tgagtacaac aggaattgga gaaggtgtag ccatacctca tgctaaaaat
    25081 tcttcagtta ctaaagcttg tatagcagca gcagtgtcaa aagaaggtat agattatgaa
    25141 tcgtttgacg gaagtttatc aaatctattt tttatgatag ctgcaccaga cggagctaac
    25201 aatactcatc ttgaagtatt atcaagatta tctacaatac ttatggatga agactttaga
    25261 aataaactta taaactcaaa ctctgaaaaa gaatttaagg aaataataga taaaaaggaa
    25321 cgagaaaaat tcagtgaaga atatcaagat gagaaagttg ctgaaaaaaa tataatagct
    25381 actaaagata ataatactaa taagtatcct caggtattag cagtaacagc atgtccaact
    25441 ggaatagcgc atacatttat ggcagcagaa agtttaaata aaatggccga aaataaaggt
    25501 gtatcaataa aagtagaaac taatggttca gcaggtgtta aaaataagct tacaaaagat
    25561 gaaatagaga atgcaacatg tataatagta gcagcagata aaaatgttga gatggctaga
    25621 tttaatggca aaaaagtcat aaaaactaag gtggctgatg gcatacacaa agcggaagag
    25681 cttatagaca aggctgtaaa tggagatgct ccaatttacc atggaggaga tggaagtcac
    25741 aacgaatcaa atgaagaaag tgaaagtgga tttagaaaag tatacaaaca cttaatgaat
    25801 ggtgtatcta atatgttacc atttgttatt ggtggaggta tacttatagc gatagccttt
    25861 ttacttgatg attatgctat taacccttca aactttggtt caaatacacc gatagcagca
    25921 ttttttaaag gaataggaga taaagctttt ggatttatgt tacccgtact tgctggatat
    25981 atagcatact ctatatctga tagaccagcg tttgttgtag gatttgtagg aggtgctcta
    26041 gcaggtgatg gtggttcagg ctttttaggt gcactacttg caggttttat agcaggttat
    26101 ttagtagaag ggcttaagaa aatatttagt gtactaccag cttcattgga aggaataaaa
    26161 ccagtattgt tatacccttt acttggaaca cttttgatgg gaattataat gacattttta
    26221 gtaatacctc cagttacagc aattaataat gcaatggttg gatttttaaa tggtttaggt
    26281 ggaacttcaa aaatagtttt aggattagta ttaggtggaa tgatggctgt ggatatgggt
    26341 ggacctgtaa ataaagcagc atatgtattt ggagttgcat cacttgaatc agggcagttt
    26401 gaaataatgg cagcagtaat ggctggtggt atggttccgc cacttgctat agctcttgca
    26461 actacatttt ttaagaatag atttactaaa gaagaaagag attctggtaa agttaattat
    26521 gtaatgggat tatcatttgt tactgaagga gctatacctt ttgcagctgg agacccactt
    26581 catgttatac cagcttgtgt tggaggttca gcagtggcag gagcacttag tatgttgttc
    26641 aacgcagctc ttcgtgcacc tcatggagga gtatttgtta taccagtggt tacccatcca
    26701 tttgcatata tattagctat agctgtaggt gctttggttg gaatgatgct tttagcatta
    26761 cttaaaaaac cattaaatca agaagtatag caattaaagg atattcaaga acttaaaata
    26821 tgatgtttta taaaaattaa tatattgctg aattatttta aaataaggat tttatgaggc
    26881 tgttatataa cgatttgtaa ttgttatctt gacagtcttt tatttttata taagtaaaat
    26941 aagtgtgttt tgctttattt gtatttaaat tgtttttaag ttagaatata aagaaaatta
    27001 tatattattt taatattcac tcgaactaga aaataatatt tg
//
LOCUS       DBGJFK010000049        26762 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.049, whole genome shotgun sequence.
ACCESSION   DBGJFK010000049 DBGJFK010000000
VERSION     DBGJFK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.049"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..1158
                     /locus_tag="ACOIAP_002415"
     CDS             <1..1158
                     /locus_tag="ACOIAP_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGZ2639297.1"
                     /translation="SNSNKISNNSIDSKFVNSRVKSIDIIRGLSIALMIVCNNPGTWM
                     RMYPQLRHAVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSI
                     LLILFGFFLNYLGNPDLNTVRILGVLQRMGLVYFVTSLVYLLLKKLNVRSSVTIITFL
                     CISAFIIVGYYIVAKPYGFELEGSLAQLVDLHFFKGHLYKPDFEPDGFLTSIVAISSG
                     MLGCMMGCVLLKENIGEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMA
                     GSYGILLSIFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNLPKLTNKVD
                     YPTTLVEWTTYELITPWAGTTWDSLVFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1412..3436
                     /locus_tag="ACOIAP_002416"
     CDS             1412..3436
                     /locus_tag="ACOIAP_002416"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2639298.1"
                     /translation="MKKTTKLLATGMVSVAMVAPNVALAVENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGPTRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNITRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQN
                     TYDWLSSQGLEEAYYIGGSQSLSSKIIDKISKIAKNGTSKNRISGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVISSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIFYKVKDKNGGTTKTAASNILKRILEKFNMQNRGIKTRTLANGNDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTTEKVKTMGTQIGIGIEDTVK"
     gene            3656..4342
                     /locus_tag="ACOIAP_002417"
     CDS             3656..4342
                     /locus_tag="ACOIAP_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGZ2639299.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4437..5492
                     /locus_tag="ACOIAP_002418"
     CDS             4437..5492
                     /locus_tag="ACOIAP_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HGZ2639300.1"
                     /translation="MIKKISTILSLVLLISISSTMWVFADAKPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEDSIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTAKLDFGSRSDVNEYISLGVV
                     SAKENMPILICNDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5608..7164
                     /gene="murJ"
                     /locus_tag="ACOIAP_002419"
     CDS             5608..7164
                     /gene="murJ"
                     /locus_tag="ACOIAP_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HGZ2639301.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVVTLLIYNNLYAFIGSGTIKEIISVGAGVLGGASVYTILIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7210..8916
                     /locus_tag="ACOIAP_002420"
     CDS             7210..8916
                     /locus_tag="ACOIAP_002420"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGZ2639302.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKDLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIIKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDVANDIIAEVNKIDDYSVIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRRVLSECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKSNGTDLIIGTDPDCDRVGIVVKDSSGEYIVLNGNQVGSL
                     LVRYIVESLVKENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEKSNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALLD
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKEGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8938..10011
                     /locus_tag="ACOIAP_002421"
     CDS             8938..10011
                     /locus_tag="ACOIAP_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HGZ2639303.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDRNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKEEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEEISKYLGTKEEVEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10023..10745
                     /locus_tag="ACOIAP_002422"
     CDS             10023..10745
                     /locus_tag="ACOIAP_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2639304.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIRVLYEQGGVYMDTDMQILKDITPLLEDNR
                     LICGYEDDGEYMNAAILGVEKGHPFFKDLLEYYEKEILTSSLFTIPKIMTHLMEKNYK
                     KIDQNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTYGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10761..11918
                     /locus_tag="ACOIAP_002423"
     CDS             10761..11918
                     /locus_tag="ACOIAP_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HGZ2639305.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWNVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11921..12760
                     /locus_tag="ACOIAP_002424"
     CDS             11921..12760
                     /locus_tag="ACOIAP_002424"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGZ2639306.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDANKIDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGDDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFVKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12775..13950
                     /locus_tag="ACOIAP_002425"
     CDS             12775..13950
                     /locus_tag="ACOIAP_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HGZ2639307.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHRFKGRNIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13979..14728
                     /locus_tag="ACOIAP_002426"
     CDS             13979..14728
                     /locus_tag="ACOIAP_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGZ2639308.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14750..15658
                     /locus_tag="ACOIAP_002427"
     CDS             14750..15658
                     /locus_tag="ACOIAP_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGZ2639309.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALKGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15706..16458
                     /locus_tag="ACOIAP_002428"
     CDS             15706..16458
                     /locus_tag="ACOIAP_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGZ2639310.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENIGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16412..17779
                     /locus_tag="ACOIAP_002429"
     CDS             16412..17779
                     /locus_tag="ACOIAP_002429"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HGZ2639311.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWARDILQQIYEPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEEAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKVKDMEELGIEY
                     YSIGR"
     gene            17785..18876
                     /locus_tag="ACOIAP_002430"
     CDS             17785..18876
                     /locus_tag="ACOIAP_002430"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2639312.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSVKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLTKELGIEDDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLSMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18959..20872
                     /locus_tag="ACOIAP_002431"
     CDS             18959..20872
                     /locus_tag="ACOIAP_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGZ2639313.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNVFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFMATLAYLI
                     PVYIINKLLGFDYPIIFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKISNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSNIKEVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVDIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21063..21767
                     /locus_tag="ACOIAP_002432"
     CDS             21063..21767
                     /locus_tag="ACOIAP_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing C40 family peptidase"
                     /protein_id="HGZ2639314.1"
                     /translation="MNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAELTNSPMSA
                     TVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKTVDNVTGWVNGDYL
                     TIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNSFDCSGFTSYVYKNGAGVNLPRVS
                     RSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGNSKFIHSPQTGDVVKVTSMAP
                     GTNYARRLITATRVLQ"
     gene            22068..24179
                     /locus_tag="ACOIAP_002433"
     CDS             22068..24179
                     /locus_tag="ACOIAP_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HGZ2639315.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANNPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGNGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVSWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSSSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWPTNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNSSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKNNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTNL
                     VYTAGDGINQNTLNAFLNLVN"
     gene            complement(24377..25342)
                     /locus_tag="ACOIAP_002434"
     CDS             complement(24377..25342)
                     /locus_tag="ACOIAP_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGZ2639316.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTIEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNAGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25627..26583)
                     /locus_tag="ACOIAP_002435"
     CDS             complement(25627..26583)
                     /locus_tag="ACOIAP_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGZ2639317.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPSLVNTILPYVKTNMNPNEIISLGKELLSIGNLDLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
BASE COUNT        10547 a         2944 c         4787 g         8484 t
ORIGIN      
        1 agcaatagca ataaaatttc aaataatagt atagattcta aatttgtgaa tagtagagtt
       61 aaatcaatag atataataag agggctatca atagccctca tgatagtttg taataatcct
      121 gggacttgga tgagaatgta tcctcaactt agacatgctg tatggcatgg tgtaacactt
      181 gcagattttg catttccttt ttttgttata tccttaggtg ttacaattcc aatatcaata
      241 aatagtaaac taaaaaataa taaatctaca ttaagtataa tacttagtat attcaagaga
      301 agtatcttat tgatattatt tggatttttc ttaaattacc taggaaatcc tgatttaaat
      361 actgtaagaa tacttggagt acttcaacgt atgggactag tctattttgt gactagctta
      421 gtatacttac tactaaaaaa attaaatgtt agaagttctg ttacaataat tactttctta
      481 tgtatatctg catttataat agtaggatat tacatagtag caaaacctta tgggtttgag
      541 ttagaaggtt ctcttgcaca attagtggat ttacatttct ttaaaggtca tttgtacaag
      601 ccagattttg agccagatgg ttttttaact agtatagtag caatttcttc aggaatgttg
      661 ggatgcatga tgggatgtgt gcttttaaaa gaaaacatag gagagtataa aaaattcttt
      721 aaaatattag ttatgagtat tattttacta ataggtgctt ttatatttaa tcagtatttt
      781 ccatttaata aaagattatg gtctagctca tttgtacttt taatggctgg aagttatggt
      841 atattactgt caatatttta ttttatatgt gacatcaaaa ataaaagtaa aatatttacc
      901 ccaataatag cacttggaag tagccctatt tttacatata tgtgtctcga gatattaagc
      961 catgtttttt ggaaccttcc aaaacttaca aacaaagtcg attatccaac taccttggta
     1021 gagtggacta catatgaact tataactcct tgggcaggta caacttggga ttctcttgta
     1081 ttttctttat tgtatgtcct attctgggtt atagtaatgt ctattatgta taagaaaaaa
     1141 atatttatca aaatttagtg caatattttt agacgctaaa gtctttgttt tgtttaaata
     1201 tacggaaact atcaaatata atcaaaattt cccctcgata aaatttaaaa accatgccat
     1261 aaaagattac aaaaagttta caatttgtaa tttttgtgct ataatgaaaa aagatttaca
     1321 taatattgaa tttatgtaat ataaaacaag cttaagatgt attaaaaaag atttaaagat
     1381 ttaaaggtcc aaaaaattta ggggggatat gatgaaaaaa acaacaaaat tattggcaac
     1441 aggaatggtg tctgtagcaa tggtggcacc aaacgtagct ttagcggtgg aaaatactac
     1501 tgcaaataca gaatctaact cagatattaa tataaattta caaagaaaaa gtgtagtgtt
     1561 aggaagtaaa tctaatgcaa gtgtaaaatt taaagaaaaa ttaaatgctg attcaataac
     1621 attaaatttt atgtgttatg atatgccact tgaagctact ttaaattaca atgaaaagac
     1681 agattcatat gaaggtgtaa taaactataa caaagaccca gaatacttaa atgtatggga
     1741 acttcaaagc ataaaaataa atggcaaaga tgaacagaaa gttttaaaca aagaagactt
     1801 agagtctatg ggattaaatc ttaaggatta tgatgttaca caagagttta taataagtga
     1861 tgcaaattca acaaaagcag taaatgaata tatgagaaaa acttctgcac cagtaaaaaa
     1921 acttgctggg cctactagat ttgaaactgc tgttgagata agtaaacaag gttggaaaga
     1981 tgggtctagt aaggttgtaa tagttaatgg agaattagca gcagatggaa tcacagctac
     2041 tccacttgca tctacatatg atgcaccaat attacttgca aataaagatg atataccaga
     2101 aagtacaaag gcagaattaa aacgtctaaa cccaagtgat gtaataatca taggtgatga
     2161 tggttcagtt tcacaaaagg cagtatctca aattaaatct gctgtaaatg taaatataac
     2221 tcgtattggt ggagttgata gacatgaaac atctttactt atagcaaaag aaatagataa
     2281 atatcatgat gttaataaaa tatacatagc aaatggatat gctggtgaat atgatgctct
     2341 taacatttca tcaaaagctg gtgaagacca acagcctata atattagcta ataaagattc
     2401 tgtaccacaa aatacatatg attggttatc ttcacaaggt ttagaagaag cttattacat
     2461 aggtggtagt caaagtttat catcaaaaat tatagacaaa atatctaaaa tagcaaaaaa
     2521 cgggacttca aaaaatagaa tttctggagc agatagacat gaaacaaatg caaatgtaat
     2581 taagactttc tatccagata aagagttgag tgcaatgtta gttgcaaaat ctgacataat
     2641 agttgattca ataacagcag gacctttagc agctaaatta aaagctccaa tacttataac
     2701 tccaaaaact tatgtttctg cataccatag tacaaattta tcagaaaaaa cagcagaaac
     2761 agtatatcag attggtgatg gaatgaaaga tagtgttata agttctatag catctagttt
     2821 gtcaaaacat aatgcaccaa cagaaccaga taactcaggt tcagcagcag gaaaaactgt
     2881 agtgatagac ccaggtcatg ggggttctga ttcaggggca acaagtggac taaatggtgg
     2941 agcacaagaa aagaaatata ctcttaatac agcattagca actactgaat atttacgttc
     3001 aaaaggtata aatgttgtta tgactagaga tacagacaaa acaatggctt taggagaaag
     3061 aacagcatta tcaaatacaa taaagccaga tttatttaca agtatacatt acaatgcatc
     3121 taatggagct ggtaatggcg tagaaatatt ttacaaggtg aaagataaaa atggtggaac
     3181 aactaagact gcagcatcaa atatattaaa aagaatacta gaaaaattta acatgcaaaa
     3241 tagaggaatc aagacaagaa cacttgcaaa tggaaatgat tacctatatg tgttaagaaa
     3301 taataattat ccagcaatac ttgttgaatg tgcatttatt gacaataaga gcgatatgga
     3361 taagttaaat actacagaaa aagtaaaaac aatgggaact caaataggca taggaataga
     3421 agatacagta aaataaaata aaaaatatta aagcaaaaca tatcatctcc tgttataatg
     3481 taaaatataa caagagatga tatatttttg taaagaatca aattgtttac aatgatgttt
     3541 cttgtattga taatctgctc attattgagt ataatataga aataagtcaa aaataagata
     3601 gaaataagtt gaaattaaga attaaaaaaa tttttattcc aatatggagg taactatgtc
     3661 tggatatact aatgatgagt gtgaaatacc taaaattaaa agctatccag gggcagataa
     3721 agaaattgca agcgagattg actatagcat agtaaaagga acagttttat ttgacttgta
     3781 ccaaagaatt atggatttag ttttatctat aataggactt gtgataggtt tacctttaat
     3841 agcaatattt ggaattctta ttaaaataga ggacaaagga ccaataactt ataagcaaga
     3901 aagactagga aaatgcggga gaagattcta tatatataaa ttaagatcta tgagaacaga
     3961 cgcagaaaaa tttggcgcac aatgggctga aaaagatgat cctagaataa ctaaggttgg
     4021 aaagtttatt aggaaaacta gaattgatga gattccacag ctgtttaata tattaaaggg
     4081 ggacatgggc ttaataggtc ctagaccaga gagaccgaac tttactgttc aatttaatga
     4141 ggaaatacct ggatttatca acaggctcgc tataaaacct gggcttacgg gttgggcaca
     4201 agtaaatggt ggatacgaaa tcactcctga agaaaaactt aaagaagata tttactatat
     4261 aaaaaatagg agtatattac ttgactttaa gatactcttt aaaactgtta aagtagtatt
     4321 gacaggagac ggagctagat aattttaaaa tattagatta ctaatcaatg aaaaagctct
     4381 ttaaaaagag cttttttatt gtcaaaaaat acaaaaaaga aaaggaatga gaacttatga
     4441 ttaaaaaaat ttctactata ttatcgttag ttttgttaat ctctatttct agtactatgt
     4501 gggtatttgc agatgcaaag cccaaaagag agttgataga agggagtata ccagagattt
     4561 cgacagaatt aaataaaaga gcatttaagg attctaaaga agtaattctt gtaaatgaag
     4621 attcaattgt agatagtata agtgcaacac ctttagcata tgcaaagaat gctccaatag
     4681 ttgtaactaa gagtaaaaat cttggtagag taacaagaaa ttatctaaaa gaactaggtc
     4741 cagagaaggt tacgatagta ggtggtttaa aggcagtatc taaagatgct gaacgtaata
     4801 tagaaaaaat gggaatgaaa gtagaaagaa taagaggaaa agacagatat gatacatctt
     4861 taaagatagc tagagaaatg tacagaacag taggatttga tgaagcattt ttacttagct
     4921 caacaacagg attagagaat gccatatctg tatattctta tgccgctaaa agtggaatgc
     4981 caataatatg ggctaaagat gaggggtttg aagaacaaat tgatttctta aaaggtaaaa
     5041 atcttaaaaa aatatatgca ttaggtgatt caaaagaatt tattgcagag attgattcta
     5101 acttaaaaaa tatagagggc ataaagcaaa taaataagtc tagtacaaat gttgatttaa
     5161 taaagaagtt ttatgatgaa aaagatataa agaaaatcta tactgctaag ttagactttg
     5221 gtagtagatc tgatgtaaac gaatatattt ctttgggagt agtatcagca aaagaaaata
     5281 tgccaatact gatttgtaat gataatttaa gtcgtgcaca agataaattc ttgaaagata
     5341 gcaatataaa tgatgtagtt gaagttgggt acacagtagg tgattatagt ctatttaaga
     5401 gcatatttaa tctaacattc ttatcttgta tagtattaat actattatta ctattgatta
     5461 catttagggc acttagatat gagtcgaaat agtttttgat ttattaagga agcttttcat
     5521 aggttaaatt tacttaatta gaataatgtt tataagcagt tttaaaagtt ctacttttag
     5581 agtttaaatt agataaggag aaagaagatg tcaaaaacag ctaaagcagc attgtggatt
     5641 atggcagcca ctatgttttc aaaagtatta ggtttcctta gagagcttgt acttgcaaat
     5701 ttctatggaa caggtatgta tgcagatgta tttgtactaa cattaaatat acctggttta
     5761 atcatagcag tcataggttc tgcagttgct acaacttata tacctatgta ctttgagaca
     5821 aagaaaagac ttggagatga aggtgcctta aaatttacta ataatgtttt aaatatatgc
     5881 tatataatgg ctatagtaat agctattatt gggcttttat ttacagagca atttgttaca
     5941 gtatttgcag caggatttag aaacgaccct gcaaagttcc aagcagcaat attatttact
     6001 aaaataatga tttcaggagt tttattcctg agtggaagta aaatatttag ttcgttttta
     6061 caggtgaatg acagttttgt aattcctggg cttataggaa tcccatataa tattataata
     6121 atagcagcaa tagcactaag tgcaggtaaa aatgtatgga tactaccagc aggagcacta
     6181 ttggctatgg cgagtcaact attatttcaa cttccatttg catttaagaa gtcctataag
     6241 tataagccat atataaattt aaaggatgag tccataaaag aattagtcaa tctagtattg
     6301 cctatgttgg taggagtagc tgttggacag ttaaatatat ttgttgatag attattggca
     6361 actactttgg gtgatggaaa gctgtctgct cttaactatg caaataggct aaatgagttt
     6421 gttatggcat tatttgttac atctataata acagttatat atcctaagtt agcaaaaatg
     6481 tctggtaaag ataataaaga aggatttata agtactattg taaaatcgtc aaattgtatt
     6541 atattggtgg tgcttcctat atctatagga gctattatat tagcagagcc tcttgttagg
     6601 atattattcc aaaggggtaa atttgatgcg ttatcaacag accttacatc tatagcgctt
     6661 agactatatt cactaggttt attggcctgt ggagtaagag atgttttata tagggcattt
     6721 tactctcttt cagatacaaa aacgccaatg ataaatggaa gtatagcttt aataataaat
     6781 atagttctta atttaatatt gataagacca ttaggtcatg caggtattgc catatcaact
     6841 agtacatcca atataattac agttatatta ttatttatat ctcttaaaaa gaaaaatgga
     6901 tattttggag gagataaaat tataaagact ggtctaaaaa gtttagtagc atctggtgtg
     6961 atggcagtag tcactttatt gatatataat aatctatatg catttatagg ttcaggaaca
     7021 attaaagaaa ttatatcagt tggtgcaggg gtactaggtg gagcttctgt atatacgata
     7081 ttgatagttt tatttaaggt agaggaaatg gatttagctt ttgaattttt aagaaaagga
     7141 aaacaaaaac tacttagaag atagattctt actttgaaat tttaaattag agtcagaaag
     7201 gatgaaaata tggattataa gaataattat gagatgtggt taaattctcc ttattttgat
     7261 gagcaaacga aaaatgagct attaagcata aaagatgatg aaaaagaaat acaagataga
     7321 ttctataagg atttagagtt tggaacaggt ggtttaagag gtataatagg agcgggaact
     7381 aatagaatca atatttatac tgttagacgt gcaacacttg gagttttaaa ttatatcatt
     7441 aagactcaag gagaggaagg taaacaaaag ggaatagtta tagcacatga tagtagatac
     7501 atgtctaggg agttttgtat agaagtagca aagactttaa gtgcttatgg tgtaaaggct
     7561 tatatttttg aagaattaaa gcctacacca gaactttctt ttgctgttag atatttaaag
     7621 tgtgctatgg gaatagtaat aacagcaagt cataatccta aagaatacaa tggatataaa
     7681 gtatatgact cagatggtgg tcaaatatgt atagatgtgg caaatgatat aatagcagaa
     7741 gttaataaga ttgatgatta cagtgttatt aaaagtatag attttgaaga agctttatct
     7801 aaaaatttaa taactatatt agataatgag gtagatgatg aatttataaa agctgttaag
     7861 aaacaagttt taagacaaaa tataatagat gaatatggaa aaaaattgaa aataatatat
     7921 acacctattc atggtacagg aaataagcca gtaagaagag ttttaagtga atgtggcttt
     7981 gaaaatgtaa tggtagttaa ggagcaagaa ttgccggatt ctaatttttc aacagtaaag
     8041 tatcctaatc ctgaagaaaa atcagtgttt aatatagcta ttgaaatggc aaagagtaat
     8101 ggtactgatt tgataatagg gacagaccct gattgtgata gagtaggtat cgtcgtaaaa
     8161 gattcaagtg gtgaatatat agtcttaaat ggaaatcaag ttggttcact cttagttaga
     8221 tatatagtag aaagtttagt caaagaaaat aaacttccta aaaacaatcc tacaataata
     8281 aaaactatag ttacatcaga actaggtgct aaaatagcaa aggcttataa tgtagattgt
     8341 ttaaacactt taacaggatt taaatttata ggagaaaaaa taaaagcgtt tgaaaaaagc
     8401 aatgatagaa gctttataat gggatatgag gaaagctatg gttacttaat tggaactcat
     8461 gctagagata aagatggtgt tgtatcttca cttatgatat gtgaaatggc agcatactat
     8521 tcttcaaaag gtatgaactt gtatgaagct ttgctagata catataataa atttggatac
     8581 tacaaagagg acttaaagtc agtgacttta aaaggtatag atggaataaa aaaaataaaa
     8641 gagatgatgc tttactttag aagtgttaaa atagataatg tggctgatgt aaaagtagat
     8701 aaaattttag attataaaga aggtgttgat gatttaccta aatcagatgt acttaaattt
     8761 ttacttgaag atggctcttg gatagctata agaccttcag gtacagaacc taaaattaaa
     8821 ttttactttg gagcaaattc agacaatcaa gaagatgtag aatttaaatt gaacaattta
     8881 atatcttata tattaaatgt agtggattct atataagagg ctaaggggag ataaataatg
     8941 aaagtatata atgtcataat ggctggagga ggaggaactc gtttctggcc acttagtaga
     9001 caagaagtac ctaaacagct tataaattta agtggagaag atgctttaat aaacgaaact
     9061 ataaacagaa tagattctct agcaaaaaaa gatgatttat ttatagtaac caatgagaaa
     9121 caattggaag ctttaaagga tatagtaaaa gataagtgtt tggataggaa tatattacca
     9181 gagccatgtg ccagaaatac agcagcagct ataggctttg cagcatttaa tataatgaaa
     9241 aaatatggtg atggtgtcat gtgtgtatat ccagctgacc attatataaa agaggaaaaa
     9301 gaatttaaat ctattttaga aaaagctatc tatatagcag aaaataatga taaactagta
     9361 actattggga taactcctac atttccatca acaggatatg gatacataaa ttttaataga
     9421 gaaaacacga tagaggatgt tgcatatgag gtagtagagt ttgtagaaaa gccaaactat
     9481 gaaattgcta aagaatatgt aaactctaaa aagtatgtat ggaatagtgg catgttcgta
     9541 tggaaggtat ctaaaatatt agaagatttt aaaagatact tgccaaaagt atatgagaaa
     9601 ctagaagaga taagtaaata cttaggaaca aaagaagaag tggaaaaaat aaaagaaata
     9661 tacccaacta tacaatcaat atctatagat tatggtatta tggaaagaag taatgatgtt
     9721 atagtagttc ctggtgattt tgggtggaat gatgttggct cttgggattc tctaggtgca
     9781 atatatccaa ctgatgatga aggtaacatc aaaagaggtg aaaatattac tatagatact
     9841 aaaaattcaa ttatatattc agatgataaa ttaatatcga caataggtat tagtgatttg
     9901 atagtagtat ctacgaatga tgcagttatg gtttgtagaa aagataaagc tcaagatgtc
     9961 aaaaaaatag tagagcagtt aaaagaagaa gatagacaag aatatatgta ggaggtgttc
    10021 atttgattcc taaaaaaata cattatgtat ggtttggtgg tccaaaagga aatatagaaa
    10081 atatatgtat aaattcttgg aaagaaaagc ttccagaata tgagatagta gagtggaatg
    10141 aaaaaaactt tgatatagag aaagaaataa aaggaaataa gtttttggaa gaatgttata
    10201 aaagaaagct ttgggcattt atatcagatt atacaagaat aagagtactc tatgaacaag
    10261 gtggagttta tatggataca gatatgcaaa tattaaagga cataactcct cttttagaag
    10321 ataataggct tatatgtgga tatgaagatg atggagaata tatgaatgca gctatactag
    10381 gcgtagaaaa aggacatcct ttttttaaag atttactaga gtactatgaa aaagagattc
    10441 tgacttcttc attatttaca ataccaaaga ttatgactca tcttatggaa aagaattata
    10501 aaaagattga ccaaaataat tatgaagaag gaatacgtgt ttacgataaa gaatattttt
    10561 atccttttgg atttaaagaa gactttacac ccgagtgtat tacagaaaac acttatggta
    10621 tacattggtg gggaaaaagt tgggctaaaa agagaaatta tttcttagaa agcaaacact
    10681 taacaggtgt aaataagata tggaagtgtt gtaaaatatt tgcaagtaat actttacgaa
    10741 gctaaaaggg agaaagtaaa atgaagactt taaacgatga tagaaatatt atgattagaa
    10801 aatatcttta tatatttgtt ttgtttatca tattacttag aaagtatatg atatcattta
    10861 ttgacccaaa tatggatata gggatgatta aatcagcgtt attttattct tcaataggaa
    10921 tactaatgct acttttttta tttgataaga gaaaaagtat aacagaaatg gtactagttg
    10981 gagtttgtgt cttactttat ttattaaata gggaaggagc tatattatta atcgttttat
    11041 tagctgtatc agctaagcaa atagatgata aatttatagt taaaaattat ttaataatat
    11101 cggcatgttt tttaatggta gctatattat tatttaattt atttccttca ttaatattta
    11161 atcaggaagt ccactataga tatatagaaa agatagatat gcttgttaca agaatggatt
    11221 ttggacttgg taatccaaat agtgtatttt atcatatggt tactatatat gcagcatata
    11281 tattcttaag atataaagac tataataaat gggatagaat aattttattt ggttctgcat
    11341 tttttgttta tcaaaccaca tatagtagaa ctggattttt tactatatta gcaggattaa
    11401 tatttgtaga aataataaga tggatagaca taaaaaaaat aaaaggacta ccaatgcttc
    11461 taaagacatt accaataata cttactttat ttagtgtaat tattggtaca gtatttgata
    11521 agagtacttt attaaataga ttattagcaa gtaggcctaa gttctggaat gtatacttgg
    11581 ctgaaaaggg gaactttcta aaaccttttg gaaattcata tagtcctgct ataaaagcaa
    11641 ctaatccgtt agatagttct tatgtatata taattagtgt actaggagtc gttgcttgta
    11701 tattatttat gtatttgatg tataaaggaa tagaaagctt tatagaaaaa gataaaaaag
    11761 catatttagt agctttattt atatttttac tatactcttt tgcagaaaat ttattattag
    11821 aagcttcatt tagttttgca gtagtattac taataaaaga agtgatatta aatgataaaa
    11881 gggaaataga tttgtggaag atgaaaagta ggaggtagta atgttaatat cattaataat
    11941 gccaacatta aatagatatg atgatatata cttacttatg gacagcttag aaaatcaaac
    12001 ttacaaaaac tttgaactta tagtagtaga ccaaaatgat aatagcaaag ttaaagaaat
    12061 agttgataaa tacattgata agttagatat aaagtatata aaaagctcta aaaaaggatt
    12121 gagttataac cgaaatgtag gcatagacaa tgctgtaggg caaattatag gtttccctga
    12181 tgatgattgt gtctacgaaa atgatacatt agaaaaagtt ataaatttct ttaataaaaa
    12241 taaagattat aaaatataca gttgcaaaac tatggatgca aataaaattg atgcattcaa
    12301 gaaaatgtat gatggaactt gtgatatcac aagttccaac gttttggata ctataacatc
    12361 cataactttt tttattgatt ttgaaggtaa agactatact agatttgatg aaaaattggg
    12421 tgttggtgga gagtttggtg ctggtgaaga gatagattat gttttaaact tattgagttt
    12481 aggttttaaa ggaaaatact ttggagatga tataatttac catcctgcaa aaaaacattc
    12541 taaatctaaa gaaaagtatc aaaaagatta taattatgga agaggttttg gagcactttg
    12601 caaaaaggaa atagtttata gaaaaaatta taagtttgta aaggttatgg tatcaaaact
    12661 tgtaagaaat ataggaggtc ttatattgag ttccaataga gattatcata gtgccactat
    12721 aaaaggaaga attaatggat ttagacagta caagttataa tgaggatggt gtttatggac
    12781 aaggttaaat ttttaataaa tatgcttttg gcttttttta tatatccatt taataagcat
    12841 aggtttaaag gtagaaatat ctggcttata ggtggacatt caggggatat atacaatgat
    12901 aattcaaagt ttttttatga gtacatgttg aaggaacata atgatgtaga aacttattgg
    12961 gtagtaaata aagacagtaa agtatttgat aaaattccag gcaaaaaatt aataagagga
    13021 agtgtagaaa actatctgta ttattacaat tcaaaagcta tagtattttc acatgcacca
    13081 tcagcagata tagcaccata caattttgct gtacctgttc ttaattattt tcataaaaaa
    13141 acaataaaag tgtttttaaa tcatgggact ataagtttta aaaagagaaa acctatgaac
    13201 aaaaagttca aaaatattat agataactta tataaaagct ataatatagt tacagcaagt
    13261 tctgaatttg aaagaaatgt tatggtaaat gattggggaa tgttagatga ctcagtttat
    13321 ataattggaa atgccagata tgacaattta ccaacaaatg aagttgcaca aactcgagat
    13381 atattatata ctcctacatg gagagattgg ataaaattta gttcaggaaa atttacagat
    13441 acagattatt ttaaaaatat aatgaatttt ttaaatgatg ataaattaaa taaaatatta
    13501 gatgagaaag atataaatgt aaaaatttat atgcatcatc ttatgcatga gtttatagat
    13561 gatataaaag aaaatataac aggaaaacga attgtgtttt tagataaagg ggtaactcta
    13621 gcaaatgaaa tcagaaaatc agctgcaaat ataactgatt attcaagtgt agccatagac
    13681 tttttgtata tgaatagacc tatcttgttt taccaatttg atttggatga atatatggaa
    13741 aaagttgatt catatataga tttaaaaagt gaaatgtttg ggtctttggc ttacaataat
    13801 gatgaagccg tgaataaact tattgatatt attgaaaata attttgaggt tatggataac
    13861 caaaaaaatg aaagaaataa gtttttcaga tataatgata ataagaactg caagaggata
    13921 tatgattgtg tattaagtaa aattaaataa atattttata aatgatgagg aaggtaatat
    13981 gaagaagaat ttagtatcta taattactcc catgtataat tctgaaaaat ttattgaagc
    14041 aaccataaaa tcagtattaa accaaactta tcaagaatgg gaaatgttaa ttattgatga
    14101 ttgctcaaca gataatagtc ctaatatagt caaatcttat atgcaacagg atagtagaat
    14161 aaaatgtata aagactgaga ctaataaggg tgtctctaat gctagaaact tagcactaag
    14221 taaggcaaca ggacaattta tagctttttt agacagtgat gaccaatgga atagtagtaa
    14281 attagaaaaa caagtaaact ttatgttaga aaatgactat gtaatttcat ttacttcata
    14341 tgaactgatg gatgaaaatg ataaaaaatt aaacaaagta ataaaagttc cacctaatgt
    14401 agattataga agattattaa aaggaaatat cttaggatgt cttaccgttg tgattgataa
    14461 gtctaaattg gattttgaaa taagaatgag tggtgtaaga catgaagatt atgttttatg
    14521 gttatcgata ttgaaaaaag ggcatattgc tcatggaata aatgaagttc tagcgttata
    14581 tagaaaatct agcaattccc taagtggtaa taaaataaaa gctgctatgt ggacttggaa
    14641 tatatataga aatatagaaa aaataccttt atacaaagct atatactact ttattaatta
    14701 tggaataaac ggaatcaaaa aaagttagac agagaggaag atttaattaa tgtataaata
    14761 taaatttact gtatttactc caacgtataa tagagctcat ttacttgaaa atttgtacaa
    14821 tgatttaaaa gctcaaactt atgatttcaa tgattttgaa tggttgattg ttgatgatgg
    14881 aagtagcgac agtactaaag agttagttga aaaatttata tcagaaaata aattaaatat
    14941 aagatatata tacaaagaaa atggaggaaa acatactgca ataaatctag gtgtaaaaaa
    15001 tgcagatgga gagctatttt tcattgtaga tagtgatgat ggtttaatta aagattctct
    15061 tgaaattgct aatgatgagt gggattcttt agagaataaa gaaggattta gtggagttgt
    15121 tggactttgt gtatatccaa gtggagattt gatagggaca gaaatgcctg aagataagaa
    15181 aatatgtcac tttgcagacc tatattttaa gtatggcgtt aagggagata aaagcatagt
    15241 atttgtaact gatgagctta taaaatttcc ttttccagaa agaaaagaag tgagattttt
    15301 accagaaagt gtagtatgga atgaaatgtc taaatactat aaagttatat gtgtaaataa
    15361 acctatgata ataagagatt atttggatga tggtttgact aagaatatat taagtaaaaa
    15421 tgcattaaaa ggtagagcat tagagttttt atatttaata aatcaaaata catatccatt
    15481 aagtagatat ccatatatgt ggataaaaaa ttacataaat ttagccagat actcattgtt
    15541 gtctgatagt cattattttg gtgaattaag aaaagtatct gataaattgc tgtatttagc
    15601 attattccca ttaggatatt acaaatatat tggacaaaga aaattagtat ctaagtaaac
    15661 ttgttggtat agtactgcta gttgctatat aaggagagta aaaatatgaa tgagccttta
    15721 gtatcgataa ttactcctgt ttataattca gaagagtttt tatcagagac gataaagtca
    15781 atccaaaatc aaacttataa aaattggcag cttttattag tggatgattg ttctaaggac
    15841 aattcaagtg aaattataaa aagttttcga aaagaagatg ctagaataaa atatataaag
    15901 cttgaaaaaa attctggagc tgcagtatct agaaatgttg gtattaagaa tgcggaaggt
    15961 cgatttattg catttgtaga tagtgatgat ttatgggata gtagaaaatt agagattcag
    16021 atagaatata tgttaaaaga aaatataggt ttttctttta catcttatag atatatgaga
    16081 caagatgggt caaaaacgaa taaggttgca agagctccta agaaaattga ctatgaagga
    16141 ttacttagaa atactataat aggatgttct acagtggtca ttgataagga gattgtagga
    16201 gagttcagca tgcctttggt aagaagggga caagatactg caacctggtt acagttactt
    16261 aaaaaggaaa aatatgcata tgggattcag gaagatttag tgaattacag attagttgga
    16321 aattctatat caagtaacaa gataaaagca ttaaaacgaa cttggaatac ttatagaaat
    16381 gttgaaaatt taagtttacc aaagagtcta tatgtatttt gtttctatgt ttttaatgcc
    16441 attaaaaaaa gagtataagt tttatatact tggaggtaaa aaaatgaaaa tagctatagc
    16501 tgggacggga tatgtaggtt tggttacagg tgtttgtcta gcagaagtag gcaatgaaaa
    16561 tgtagtctgt gttgatgtag atgaacaaaa agttaagtca atgaaacttg gaatagcacc
    16621 tatatatgaa gaaggcctag aagaacttat ggttaaaaat tacaatagag gaagaataga
    16681 ttacactaca gactataaaa aagcttatga agatgtagat gtaatactaa tagctgtagg
    16741 tacaccagaa agaagtgatg gttcagctaa cttagattat ataaaggcag ttgcaaagca
    16801 aatagctgaa actgtgacaa aagatactct agtagtaata aaatctacag tgccaattgg
    16861 tacaaatgaa gagatagaag attatataaa tagaaactta aagaatgatg taaaagtgga
    16921 gcttgcatct aacccagagt ttttatcaca aggtacagca gtaaaagata ctttgcatgc
    16981 ttcaagaatc gttataggtg tagaaagtga atgggctaga gatatattac aacaaattta
    17041 tgagcctttt aatcaaccta taatagttac aaatagaaat agtgctgaaa tgataaagta
    17101 tgcatcaaat aacttcttgg ctcttaaaat atcatttatg aatgatattg caaatctttg
    17161 tgaaatagca ggagctaata tagaagatgt agctttaggg atgagttatg atgatagaat
    17221 aggcagtaaa tttttaaagg ctggaatagg atatggaggc tcttgctttc caaaagacac
    17281 aaaagctctt cactggttat ctgaacataa tggttatgaa ttaaaaacag taaaagcagc
    17341 aatagaagtt aatgaaagtc aaaaacttaa attggttaga aaagcttcta aactagtaga
    17401 gagttttcaa gatatgaagg ttgccgtttt gggtttgact tttaagccag atactgatga
    17461 tataagagaa gcgccatcta taccaaatat aaaatatttg ctcgaaagag gggcaagagt
    17521 tactgtatac gacccaattg gtgtaaataa tactaagaaa atatttggtg attctatact
    17581 ttatgcggat tctgtagatg atgcgataga agaggcagag atatgtttta taatgacaga
    17641 atggaaagat gtattaaatt atgatataca taaatataag gaaaagatga aaaatccttt
    17701 agttcttgat ggaagaaatt gttataaagt taaagatatg gaagagttag gaattgagta
    17761 ttattcgata ggaaggtaaa tattatgaag actgtttgtt atttagctga tgggtcaaat
    17821 cctcatactt taaaatggtg tagttttttt aaaaataaag gatatgacat tcatgtaatc
    17881 tctttaaatg gaggccacat ggaaggaata aaaatttata actttggttc taatgtagaa
    17941 gaactaaaaa atgaaaatat ttctaaaaaa acaggatact taggttcagt aaagcagata
    18001 aagaagctag taaatgaaat aaagccagat atattgcatg cacagtatgc aagtagttat
    18061 ggatttatag gaagtctact tgggtatcat ccatatatta tttctgtttg gggtactgat
    18121 atttatgatt tccctaataa tggttttata caaaaacaaa ttataaaaca taactttaga
    18181 aaagcagact atatcttttc aaatagtaga gatatggcta aagaggctaa taaatataca
    18241 gctaaacatg tagatgtaac cttttttgga gtagatatgg ataggtttaa gcctatggaa
    18301 gtagaaaaag aagatgcttt tgtaatagga attataaaga gtttagaaaa aaaatacgga
    18361 atagaatatt taatacaagc atttaagatg cttaaagatg aatataaaga taagaaaata
    18421 attcttaaaa taggtggttc tggaagtcag atggacaacc taataaattt aactaaagaa
    18481 ttgggtatag aagatgatgt tcagtttttg ggaagaatat ctccagaaaa tgtaagcaag
    18541 acttttaatt cttttgatgt aactgtgttt ccttctttaa gagagggatt tggagtggca
    18601 gctatagaat cagaagcgtg tgaagtacct gttatagtta caaatgtagg aggtcatcca
    18661 gaatctgtat gggaaaatga aacgggctta attgtagaac caaaacaacc agaagaaata
    18721 aaaaatgcta taataaaact aatggaaaat gatgaactta gacttagtat gggtaagaag
    18781 ggtcgtcaat ttgttagaga aaattatgaa gttaatttaa actttaatga tatagaaaaa
    18841 atttatgatt ctatatttga taaatataaa aaataaaatg aaaaatacag caaaagatag
    18901 atgttgttgg ctatgcttag gtgcgtagct tttgctgttt aaaggagggc ttctagttat
    18961 gcgagaaagt atagatttag agaaagaaag cttttttaat aggcttttta aaaaatataa
    19021 atttagacat ttaacactat taattctaga tatttgtagc gtactagtag cgtttcgaat
    19081 gtctttaagc ttgacaggta atttaaatgt atttaccact aatgatataa taatttcagc
    19141 ttgtatatat atagtacttc atatagtatc atttagattg tttaagtgtt acaacacact
    19201 atggagatat gcaggagaag aagaaatcat atctattttt atggcaactt tagcttattt
    19261 aattccagtt tatataataa ataaattatt agggtttgat tatcctataa tattttatgt
    19321 actaaataca atatttatta taatgtttac aagtggcgca agaatagcct atagagctat
    19381 aagaatagtc atgaataaga catattctag aggcaagatt tcaaatatcc ttataattgg
    19441 tgcaggagat gcaggagaaa tggttataca ggaactaaaa agaaatccag aacttaagaa
    19501 agtagcagtg gctataattg atgatgataa aaataaaatt ggaagaataa tccataatgt
    19561 aaaaattgta gggacaactt caaatataaa agaggtagtt gaaaagtaca atgtagatga
    19621 gataatcttt tcaatagcaa atatagagaa acgtagaaaa aaagagatta ttgatatatg
    19681 taaaaacact aactgtaaaa taaagacaat accaggaatt tacgaaatta tagatggaaa
    19741 agttgatata aaacagatta gagaagtaga tatagaagac ttgttgggca gagagcccat
    19801 aaaaacaaat ttaagagaga taagtaatta tattgaggga aaagtaatcc taataactgg
    19861 aggaggaggc tcaattggtt cagagctttg cagacagatt gcaggattta atcctaaaga
    19921 gcttattata gttgataatt atgaaaacaa tgcttactca atacaacaag aattacttag
    19981 aaaatataaa aataaattag acttaaagac cgtaatagca tcaataagag aagaaaaaag
    20041 aatggatgaa atatttaata aatataagcc agaagtagta tttcatgcag cagcacataa
    20101 acatgttccc cttatggagt cgagccctgg cgaagctata aagaataata tatttggaac
    20161 tttaaatata gctggattat cttcaaaata tagagctaag aaatttgtcc ttatatctac
    20221 ggataaggct gtaaacccta ctaatataat gggagctact aaaagagctg ctgaaatgat
    20281 tatacagact atgaatgctg aaagccagac tgaatttgtt gctgttagat ttggaaatgt
    20341 acttggtagt aatggtagtg taattccact ttttaagaag caaattgaag atggtggacc
    20401 agtgacagtt actcatccag atatcattag atattttatg acaataccag aagcagtagg
    20461 tttagttata caagctggag ctatggctaa aggtggagaa atatttgtgc ttgatatggg
    20521 agagcctgta agaatattgg atttagcaaa aaatttaatt aaattcagtg gatttgagcc
    20581 agatgttgat ataaaaattg aattttctgg tcttagacca ggagaaaagt tgtatgaaga
    20641 actacttatg tcagaagaag gtctattgga tacagagcat aaaaagattt ttattggtag
    20701 accaatagat gttgatagag aaaaaataac aaaatactta aaacttttaa gagaaattac
    20761 taacaatgaa gaggttgaaa aaatagatgg tattatgagg gaattagtac caacttatat
    20821 taaaccagaa gatgctaata tcaaagaaat tgcaacaact agagaaaagt agaatatatt
    20881 tctaatttgt aaccaggggg agcaaaaaga aacaaatatg tgctaaaaag aaacaaaaga
    20941 ttacaaaaag attacaaaaa aggttgcaat ttattttgat gtaagataga atgttaatta
    21001 ggaattggaa acgaaggaac aaaatgttaa attttcgaaa ggattaggta tttgagatta
    21061 tgatgaatat taaaaataaa aaacatatat tgaaaaaatt tatagctatg gtgttaatag
    21121 caggagttgt aacagtagaa gcaggagcaa taacagctag tgcagcagag ctaactaatt
    21181 cacctatgag tgcaacagta gaccagtgtg attttttaaa tgtaagaagt ggagctagtg
    21241 caaatgatgc agtagtagga aagataaaca caggagacaa agttgaagtc ttagaattac
    21301 attcaaatgg atggattaaa ataaaaactg tcgacaatgt tacaggatgg gtaaatggag
    21361 attatttaac tattcaaggt ggaaatgtag atgcaaaggt acaaaatgtt ttaaacttag
    21421 catttaagca acaaggtaag ccatatagat ggggagcaac tggaccaaat tcttttgatt
    21481 gttctgggtt cacttcttat gtctataaaa atggagcagg agttaattta ccaagagtat
    21541 caagatcaca agcaacagta ggaaagaaag tatcaagagc agaattaaaa ccaggagatt
    21601 tagttttctt tggttcaggc ggttcaataa atcatgttgg attgtatgta ggaaattcta
    21661 aattcataca ttcaccacaa acaggagatg tagtaaaagt tactagcatg gctccaggaa
    21721 ctaattatgc aagaagactt ataactgcta cacgtgtttt acaataataa tagatattga
    21781 tttacatagg attgaatatt aacattaagt atataattac atttaatgtt ttacatagag
    21841 atttaagagt ttagtaatat taaaatagtg atgaacgtta taaaaacagc aaagaagata
    21901 aatttctttg ctgttttttt ataataaatt atttcatatt ataatcaaat ataaaatata
    21961 aattttaact atattattca atatttgaca gataatatga attttagata tacttgataa
    22021 gaagtatatt ttagaaaaaa taaatttaaa aaattaaggg ggatgaaatg aaaaaaataa
    22081 gtatattagt attatcattg ataatgacac ttactatgtg cagtgtaagt tcatttgctg
    22141 attcgtcaaa tgataaggaa atgagagctg cttggatatc tacagtttat aatttagact
    22201 ggcctaaaac taagaacaat gaagccaagc aaaaaaagga atacacagat ttattggaca
    22261 aattaaaaag tgtaggaata aatacagcag tggttcaagt aagaccaaaa tcagatgctt
    22321 tatataaatc aaatataaac ccatggtctg aatatcttac aggtacacaa ggtaaagacc
    22381 ctggatatga cccattacca tttttaatag aagaagcaca taaaagagga atggaatttc
    22441 atgcgtggtt taatccatat agaataacta tggcagatga gagcatagat aaattgccag
    22501 caaacaatcc agcaaagaaa aatccaagtt gggtagttaa acatggaaat aagtattact
    22561 atgacccagg tttaccagaa gttagaaagt acatagtgga tagtatagca gaagtagttc
    22621 aaaattacga tatagatgga gttcattttg atgattattt ctatccagga gtaagtttca
    22681 atgatactgc tacataccaa aaatatggaa atggacaaaa taaagataat tggagaagag
    22741 aaaatgtaaa tactctactt agagatgtaa aagcgtctat aaagagtata aagcctaatg
    22801 ttgtatttgg tgtaagccca gcaggtatat ggagaaataa gagtagtgac ccaacaggtt
    22861 cagatacatc aggcaatgaa agttatgtag gtacatatgc agatacaaga gcatggataa
    22921 aacaaggatt gattgactat gtagttccac aactttactg gccaattggt cttaaagcag
    22981 cagattattc taagttagtg tcatggtggg ctaatgaagt aaaaggaaca aacgtagatt
    23041 tatacatagg acaaggtata tataagcaag gtcaatcaag ttatggtgga caaaatatag
    23101 caaaagaaat agtgcaacaa gtaacattaa atagaaagta tagtgaaata aaaggtagta
    23161 tgtatttctc agctaaagat atagcaaata gtagctctat acaaaaggat ttaaagagct
    23221 tatattctag tagcgaagaa ccagttactc caccatctaa tgttaaagtg gagaaattaa
    23281 gaggcgacga aaggtatgat acagcagtag caataagtaa aaaaggctgg cctacaaatt
    23341 cagatacagt agtattagta aatggatact ctatagttga tggtataaca tcaacaccac
    23401 ttgctacatc aaatgatgct cctatactat tggtaaataa ggataatata cctacatcta
    23461 ctaagaatga gttaaaaaga cttaatccaa gtaaagttat tttaattgga ggaaatagct
    23521 ctattggaga taaagttgag agtgagataa aagatacact gtcaaatgta tcaataaata
    23581 gagttggtgg ttcagataga tatagtacat ctttaatgat agcaaaagaa ttagtaaaaa
    23641 ataatccagt agaaaaacta tatataacaa gtggtacagg tgaagcagac tctctttcta
    23701 tagcttcaaa agcaggagaa gaaaagcaac caatagtact agtatcaaaa gataatgtaa
    23761 gtgatgaagt ttacaattgg atatcagact taaaagtaaa agatgcttat tttataggtg
    23821 gtaatctaag tatatctgat tcagtaataa ataagttgga taaagtcatt acaaatgatg
    23881 tttctaaaaa tagaatagct ggagaaaata gagaagagac aaatggaaaa gtaatacaaa
    23941 aattctatcc aaatgctgaa tactcatcaa tgtttgtaag taaaagtaat caattggtag
    24001 atgcattaac atcaggtcct ttagcagcta aattaaaatc accagtagtt atgcttggaa
    24061 atagcgtaac atctgctcag aaaactgctt tagagcctaa gaaaactaat ctagtatata
    24121 cagctggaga tggaataaat caaaatacat taaatgcttt cttaaacttg gttaattaat
    24181 aaaaaagtta atttaggata aaatttcttt tatagatgta gattaaaatg aatattatta
    24241 agaaaaatta gaaaataaaa aagaactata tgcattttgt aatcaagtgt acacagtagc
    24301 ttgaaaataa ttatgcgata tagttctttt ttactaatta atcttatact ttgtaataaa
    24361 ctttatatta aattttttat tgtttaaact ctatgtcatt aaatataaaa tcatgtaata
    24421 tgtctaaagt atctgggtca aatctaagaa cccatccagc ttttccatat ataccacctg
    24481 tactatgaat ttcatcatca ataggaaatt caaattgctt aatatttaag tcccccattt
    24541 ttaaaacttg agctcctaaa gaaagtattg cattaggctt catgttagtt ttaacatatg
    24601 gaagaactgc atctaataat cctggatatt tagtaacagg taaagtttct gttttcttga
    24661 ttatagcttg tataatctgt ctctgtcttc catctctagc aaaggctgta tcattgtgtc
    24721 tgatacgtgc aaaagatagt gcctgatatc catttagagt ctgctttcca gcgtttctaa
    24781 tgtattgtat gctaccttta tcatcacttt tattccattt ataagtctca ggaataaatt
    24841 tatttagttc tcgtatttct cctttttcaa tggtaacttc aacgccacca atagcatcaa
    24901 ttatatacat aaatgattcg aaattaacac aagcgtaatt ttgaatatca atattaaaat
    24961 tctcttcaat tgtttgtatt aataaatcag cttgtccata agcataagca tgagtaagtt
    25021 tttgtttacc atgaccaggg atgtctacat agctatcacg agctaatgat gtaagtttga
    25081 tatcattgtg cttgttatca atagtaagta tcatcatagc atctgacctt gaagaatctt
    25141 catttggtct agcatctgtt cccataagta gtatattaat tatcccatct tcatttttat
    25201 ggtcattgtt atctaataaa tcactactta tgctcgagtc atgaatagca gataatttat
    25261 aataaaaata tccatagacg cttataggga atattactac caagaaagcc agtagtataa
    25321 caaatttctt taattttgac aaaagtaccc cttctttctt ctttttcctg tatatttttt
    25381 aatagcatac acttaattat attaaagtat tgaaatatat tcaatacttg tttcagttac
    25441 aaaaaaaaga caatgatata atttataaga aaatttatcg acttatatat acaattaaaa
    25501 gtatatataa tatatttttt aaaagtaatt tatattttaa aataaaaaca caccccgtaa
    25561 atgcaaaata atttgcattt aagaggtatg tatttatcat caaattatta gtttgttttg
    25621 aaatttctaa tcttcaacca taatgtcttt aaatatgaaa tcatgcattg catctagttc
    25681 atattcctca aaaggtatta catagcctgc attacctatt tttctaccat tttcagtaga
    25741 aagaggaaat tccatagatt tcaaatctaa atttcctata cttaaaagtt cttttcctaa
    25801 agatattatt tcattaggat tcatattagt ttttacatac ggaagtattg tattaactag
    25861 actagggtat ttagtgactg gtaaatcctt aacaccattt attaaactct gtatgacact
    25921 tctttgtctt ctatctcttt catctgtact atcgtttttt cttatacgag aaaatgcaag
    25981 tgtttgatat ccatttaatt tttgctcacc agaatttctt atatatttaa gagaaccttt
    26041 attgtcattt ttattccatt tataagtttc aggtataaat ttatttaatt ctcttatttc
    26101 actcttatca acagtaacag taactccacc tagagcatca actatatcca taaaagagaa
    26161 aaagtcaact acagcgtagt tttgtatatc aagttggaag ttttcttcta tagtttctat
    26221 taataaatta gcttgtccat atacataggc atgtgttaat ttttgttctc cacgtcctgg
    26281 tatattaaca taagtatctc tattcaatga agttagttta agacttttat ttttattatc
    26341 aatagtaagt atcatcatgg catcagaacg agaaacttct tctcctggtc ttgcatctgt
    26401 acctaacaat aatatgtttg tgatattttc ttcgttttta tagtcattac tactaagcgc
    26461 ctctgtattt atactatcat cttgtatagt ttttaattta gtaaaaacat atccatatat
    26521 actaacagga aatgctataa ctaaaagggc tagaaatata acgaactttt tgagtcctga
    26581 caataatatc ccctactttc taaatttttt aattacacat agttaattat attaaaaatt
    26641 tactacataa gcaataaaaa acacaataaa ttagcataag tttgtcataa tataattatt
    26701 tttatagtat tttatagaag aaagtgtgta gttattatta attttattgg aatataattg
    26761 ta
//
LOCUS       DBGJFK010000050        26266 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.050, whole genome shotgun sequence.
ACCESSION   DBGJFK010000050 DBGJFK010000000
VERSION     DBGJFK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26266
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.050"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            103..279
                     /locus_tag="ACOIAP_002436"
     CDS             103..279
                     /locus_tag="ACOIAP_002436"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639318.1"
                     /translation="MNLNRIKEIIKKGLKKFMKVVVNLFCNKLFHRMLYVISISVVVK
                     ITMNINLYISILKY"
     gene            380..1117
                     /gene="cas6"
                     /locus_tag="ACOIAP_002437"
     CDS             380..1117
                     /gene="cas6"
                     /locus_tag="ACOIAP_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HGZ2639319.1"
                     /translation="MSRISVFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            1122..2588
                     /locus_tag="ACOIAP_002438"
     CDS             1122..2588
                     /locus_tag="ACOIAP_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639320.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKSDYKLKFT
                     CELNRNYLSLESAENIDPKYISDYILENQLFKVFKNGKKEALEKIFNNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMEINVKNIVDTVIKSN
                     IEIDKIDLEQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKRSGQ
                     VESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKSFYK
                     KLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREPGNT
                     KNLGKKMIDNGNLSNLKELLLDNISFLKPSNGTSREMDFVSSSYNIGLYIKLCWIVDG
                     GDEYKMKNYTESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQTIMH
                     VLVSNGILIGDGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            2607..3620
                     /locus_tag="ACOIAP_002439"
     CDS             2607..3620
                     /locus_tag="ACOIAP_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HGZ2639321.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIIFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYIGSTQLITNRGFLSSEFGRKYYDEKEENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            3636..4433
                     /gene="cas5"
                     /locus_tag="ACOIAP_002440"
     CDS             3636..4433
                     /gene="cas5"
                     /locus_tag="ACOIAP_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HGZ2639322.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKDVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            4460..6868
                     /locus_tag="ACOIAP_002441"
     CDS             4460..6868
                     /locus_tag="ACOIAP_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HGZ2639323.1"
                     /translation="MENIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINDILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIED
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILDEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLNTRNSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIAFIESNKEENICEGKDVKVS
                     FIKEKEIKSIVEGALENKQKILIIKNTIDSVNRTYEFLKENLSDKYSGVDIDVLHSRF
                     KFKDKKEKYSKILNGKGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKSILNNVIKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEDNFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYRLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            7307..8254
                     /gene="prmA"
                     /locus_tag="ACOIAP_002442"
     CDS             7307..8254
                     /gene="prmA"
                     /locus_tag="ACOIAP_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGZ2639324.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKN"
     gene            8273..9031
                     /locus_tag="ACOIAP_002443"
     CDS             8273..9031
                     /locus_tag="ACOIAP_002443"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGZ2639325.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRYKPGEKLEICD
                     KNNNEYICEIVNIDKSIVNLNILEKVDINRESELKIRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVAKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLTFKEAL
                     EDMKKNNINICPYENERTVPMKHALQNCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            9033..10331
                     /gene="mtaB"
                     /locus_tag="ACOIAP_002444"
     CDS             9033..10331
                     /gene="mtaB"
                     /locus_tag="ACOIAP_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0061712 - tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HGZ2639326.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INKIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRKLDVLFEQNLEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10374..10724
                     /locus_tag="ACOIAP_002445"
     CDS             10374..10724
                     /locus_tag="ACOIAP_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HGZ2639327.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDITDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10887..11066
                     /gene="rpsU"
                     /locus_tag="ACOIAP_002446"
     CDS             10887..11066
                     /gene="rpsU"
                     /locus_tag="ACOIAP_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGZ2639328.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            11096..11539
                     /locus_tag="ACOIAP_002447"
     CDS             11096..11539
                     /locus_tag="ACOIAP_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HGZ2639329.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11650..12147
                     /locus_tag="ACOIAP_002448"
     CDS             11650..12147
                     /locus_tag="ACOIAP_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HGZ2639330.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLVYLMWLVYAGFLNYFI
                     WFINK"
     gene            12340..12897
                     /gene="raiA"
                     /locus_tag="ACOIAP_002449"
     CDS             12340..12897
                     /gene="raiA"
                     /locus_tag="ACOIAP_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGZ2639331.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENVDFIDNSSEFDDYDDEEYENIVIERRKKFNVKPMSSEEAILQMELVGHNFYMF
                     RNQDNFEINIVYKRKAGGYGLIEQD"
     gene            13111..13347
                     /locus_tag="ACOIAP_002450"
     CDS             13111..13347
                     /locus_tag="ACOIAP_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HGZ2639332.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13360..14685
                     /gene="yqfD"
                     /locus_tag="ACOIAP_002451"
     CDS             13360..14685
                     /gene="yqfD"
                     /locus_tag="ACOIAP_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HGZ2639333.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRSELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEIPSNPEKRPLNDIRNEFDEDNKDNKEQNNSDENNSNQNSNSNNN"
     gene            14723..15739
                     /locus_tag="ACOIAP_002452"
     CDS             14723..15739
                     /locus_tag="ACOIAP_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGZ2639334.1"
                     /translation="MIIQKKFTIADGNFERELFGNFDENVKLIEKTLNIDVILREGNI
                     ILIGEEKNVDSALKLMNELHQTVSNGKHLDKQSISYSLSLLLEGSEQKIKELEGTIVI
                     TQRGKAVQPKTLGQKEYIKLIENNDITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRII
                     LTRPAVEAGESLGFLPGDLKDKVDPYLRPLYDALFEMLGADKFNKYLERGTIEVAPLA
                     FMRGRTLDNSFIILDEAQNTTSEQMKMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLI
                     QATEILKGVPGIGSIMLTDRDVVRHELVQRIIRAYEKHDKREEFKKEERKKAKMQEKT
                     FKRK"
     gene            15796..16257
                     /gene="ybeY"
                     /locus_tag="ACOIAP_002453"
     CDS             15796..16257
                     /gene="ybeY"
                     /locus_tag="ACOIAP_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGZ2639335.1"
                     /translation="MDLILDDRQDKLEVSEELLEKIKDIILECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            16263..16982
                     /locus_tag="ACOIAP_002454"
     CDS             16263..16982
                     /locus_tag="ACOIAP_002454"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004143 - ATP-dependent diacylglycerol
                     kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGZ2639336.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            17101..17502
                     /locus_tag="ACOIAP_002455"
     CDS             17101..17502
                     /locus_tag="ACOIAP_002455"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGZ2639337.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSSFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHDIKDLLPNYFSGNDLK"
     gene            17567..18460
                     /gene="era"
                     /locus_tag="ACOIAP_002456"
     CDS             17567..18460
                     /gene="era"
                     /locus_tag="ACOIAP_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGZ2639338.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18472..19851
                     /gene="mgtE"
                     /locus_tag="ACOIAP_002457"
     CDS             18472..19851
                     /gene="mgtE"
                     /locus_tag="ACOIAP_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HGZ2639339.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEQREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIVARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLKEQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            19924..20079
                     /locus_tag="ACOIAP_002458"
     CDS             19924..20079
                     /locus_tag="ACOIAP_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HGZ2639340.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            20045..20818
                     /gene="recO"
                     /locus_tag="ACOIAP_002459"
     CDS             20045..20818
                     /gene="recO"
                     /locus_tag="ACOIAP_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGZ2639341.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTVSLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20811..21410
                     /locus_tag="ACOIAP_002460"
     CDS             20811..21410
                     /locus_tag="ACOIAP_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HGZ2639342.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21570..22448
                     /gene="glyQ"
                     /locus_tag="ACOIAP_002461"
     CDS             21570..22448
                     /gene="glyQ"
                     /locus_tag="ACOIAP_002461"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGZ2639343.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22448..24514
                     /gene="glyS"
                     /locus_tag="ACOIAP_002462"
     CDS             22448..24514
                     /gene="glyS"
                     /locus_tag="ACOIAP_002462"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGZ2639344.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKDEYIFATIKQDGKETSEVLKDILPDTIKSVVFPKAMRWGGKNLKFARPI
                     RWIVTLLNDKVLEFDLEGIVSSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIVGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNREEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVRVKQ
                     LLKDKKYGVALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(24681..26228)
                     /locus_tag="ACOIAP_002463"
     CDS             complement(24681..26228)
                     /locus_tag="ACOIAP_002463"
                     /EC_number="1.8.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HGZ2639345.1"
                     /translation="MDNFKKILLNEIPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSHHQLNKIYEMAIKHNLDKIHLTTRQAIQLHDLSIDSIVDI
                     MKEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEAFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEQYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLKKFKEYYKLEKENGG
                     LELNIEEIDYSKSGVKICIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLNTLLKELDN
                     IENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGVST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASTGNFYEWVNSNDDILNK
                     ITDKYKI"
BASE COUNT        10731 a         2607 c         4728 g         8200 t
ORIGIN      
        1 ggtcaaatta attataaaga aataattatt gactctatat aagtaatatc atataatgta
       61 aatatgattt aataaatata aaaatacata gggggaataa atatgaattt aaacagaata
      121 aaagaaataa ttaagaaagg attaaaaaaa tttatgaaag tagtagtaaa tttattttgt
      181 aataaattat ttcatcgcat gttatacgtt atttctattt cagtagtagt aaaaatcaca
      241 atgaacataa atttatacat atctatttta aaatattaac tattttgtaa atataaaaaa
      301 ttaatagata tatatctatt aattttttat attacaaata gagaataatg gattatacta
      361 gaaagtagga ggtgaaaata tgagtagaat ttcagttttt atggagtcat gtaatggcaa
      421 atttccaaat gaaaattcaa tgttgtcagt ttcctttata aaaaatattt taaacgcaga
      481 aaacaaagat tttgctaaaa atatatttaa ctatggggaa gaaagaaaaa acaataagca
      541 aataaaggat ataaatacag ccatctacat accaaatctt ataagaagca aaaatgagtt
      601 gcttgttgat ggagatataa tattcaatat aagtttttat aattattcta tgttcagtaa
      661 attatacaat ggaattttaa aagtaaagga gctagaatat aaaggttata gatttaaaat
      721 aaaaaatata aaaatacata aagaacatga gataaaagaa aatggtgtta tatttaaaac
      781 tatgtctcct ataatagtaa agaataaaga aggtaaatat ttagatgtag aagattcaaa
      841 ttatatagaa tgtttaaact atatagctaa tctaactctg gagagtataa gaggtagtgg
      901 gcttagaaag ccattggaat ttatacctct taacttcaaa aaaagagtgt taaaagaaaa
      961 gattcgtgga tttaaagaga gagaatttta ctatataaat gcttatgcag gaacattttt
     1021 tttaaaagga gatatggaag atttaaatgc actgtataaa atggggattg gatatagaag
     1081 gacggaaaat gcaggaatgg ttgatatatt aaagtagcga ggtgagagaa ataaaagcta
     1141 aattttatag atcaggtgat attgtaagag atattggcat tgtttacttt tatgaattac
     1201 taatggattt aaaaaacgaa ctagaaaaaa gtgattataa attaaaattt acttgtgagt
     1261 taaatagaaa ttatttatct ttagaatctg cagaaaatat agaccctaag tatatatctg
     1321 attatatatt agaaaatcaa ctttttaagg tatttaaaaa tgggaaaaag gaagccttag
     1381 aaaaaatatt taataatata gataatttaa cgtatgtaaa ttttattgaa gaattggata
     1441 aatcttctgc aactgctaaa caaaaggaag atattaaaaa agattttaaa aacagaagat
     1501 ttccatatgt tagaaatagt ggtaagtatg gattaaacac gagtttagaa aatatggaaa
     1561 taaatgtaaa aaacatagtt gatactgtga ttaaatcgaa tatagaaata gataaaattg
     1621 atttagaaca atatgaagaa aaagatagtg tatgtaatgt ttgtaatata aataaaacaa
     1681 caaaactaga tattgattta agagagagaa aggactctaa gtataacttt ttatttagag
     1741 gtgcagaaaa atcaggcttt aaaagaagtg gacaagttga aagtaatatt tgttttgagt
     1801 gtgaattttt caacttaatg tgtcttttat atataaattt aaaaagacca atggtttttg
     1861 catatacgaa tgatttaagg gaattagcat ttttaaatca taagataatg cttaaaagaa
     1921 aaatgtattc agataaatca ttttataaaa aacttttaca tgaaaaaata agttcaatta
     1981 gactatatag gtttgatatt gatacgaata aaggtataat tctaaagttt gattctatta
     2041 tagagtataa agaattacta aaaaaaattg aacttataga tattatagat aattacaatt
     2101 tctcaagaga gccagggaac actaaaaatt taggtaaaaa aatgattgat aatgggaatt
     2161 tatcaaattt aaaagaatta ttacttgaca atataagttt tttaaagcca tcaaatggaa
     2221 cttctcgaga aatggatttt gtatctagtt catataatat cggcttatat ataaaattgt
     2281 gttggattgt agatggaggg gatgagtata aaatgaaaaa ctatacagaa agtaatttaa
     2341 tatattcaag agtaggtaaa gacttattta ataaaatgac agatgaatcc agaagaaaaa
     2401 atttttctat gaaagtgatt caactactta aatctaatga tagaactcag ttatttcaaa
     2461 ccataatgca tgtgttagtt tctaatggaa tcttaatagg agatgggttt gtagaaggtc
     2521 taatgcagag ttctgaatta gaattaaata caaatgtagg tctatttatt caagaaataa
     2581 tgaaataaaa agggggaaaa tttaaaatga atgaaaaaag agtaaaagga gtaacattaa
     2641 ctatactgac agaaagccca gttccacttt catatgacca aggttatgga aattatacac
     2701 caataaaaaa agaacaatat agagaaaaaa tacatgcaaa aactagtata gctacaataa
     2761 catatgactt aagaagaatg ctacatcaag aatatggttg gaatttaagt aatattattt
     2821 ttgggaaaaa aggaaatata tatccatcta ttaagaaaaa tgtaggatgt gtagatgaaa
     2881 atggattaga gactgatgta tttggttatt tgataccact taaagataaa ggttctataa
     2941 gtaaagcttc tccacttaga ataatacctt ttaggtcatt aaatccatat ataggttcaa
     3001 cacagctaat aacaaataga ggttttttaa gtagcgaatt tggtagaaaa tattatgatg
     3061 agaaggaaga aaatgaagta cttagagatg aaaactttcc aacaacacaa gcattggcaa
     3121 tagaagagac tttatcagat tactacgttt atacaataac attggagctt gatagaatag
     3181 gagtagtaga agtagaagat gggaagttac ttttaccaga agaaagaaaa tttatgagta
     3241 aggaattaag agaaaaggca gtaaaagata tattagatgc aattactgtg tttacaagaa
     3301 acataaaaca ttcatcagta ctattaaaac cacttgcagt aatgggtgga gcttttgata
     3361 aagttgtacc gtttttttgg gatgatgtag attacaatgc tgatagtggt gagataaatt
     3421 tagagggagt tatagaaact atagaaagtt atagccttaa agaaagtaat acaatacttg
     3481 ctattaatga cagattaaaa atttctaata aaaaggaatt aaataagttt aatttaagta
     3541 aataccctgt aaaagagatt aaaaatctag cagacagatt ggaaattgga gaagataata
     3601 tgtggtattt aaaagagtag gaggtttttt gaattatgaa agtattacaa tgtaaactta
     3661 agcaaccaac tgctcactat agagacccaa aagtatttca aaatgaatat ataagtactt
     3721 taaatttacc atctaagact acaataatgg ggatgataac gtatttatgt gatagaagat
     3781 taaactctga tatagatata ggaataattg gaacacatca tcatagagaa ctagaatttt
     3841 caagaggaga gaatattgat ttttggaatg aatatacaaa tatgagaaaa ggtaaagata
     3901 aagaaaagtt tttgcttaaa ggaaactact atgattacta taaagaacat aaagctcaaa
     3961 atagcatatt aaactatgaa gttcttaaag acgtagaact gactatattt atttcttgca
     4021 aggatgatga agaacttgaa tttattagaa aaaagcttga aagtccatgt aaatatgcaa
     4081 atttaggaag aaaagaagat tttgtaatac caagtgaaaa agggtgtttt gtgaaagaag
     4141 ttgagttaaa agaggttata cctatgaata ctcgtgatgc tataaaagaa aatataaaat
     4201 taaagaatac atatgtaaga gttgacttaa gagataaaga gaatgtcgag actataataa
     4261 atcaaggtgt attgattgca ttgcctcata aatataaaga tttagaagca aatagagacg
     4321 atagagttta tgagttttgc cattatatat atgttgataa tgatggtata tatcctaaaa
     4381 atattaaggt aaatgtatgt attgatacaa aagaagtttt tacatggctt taaattattt
     4441 tgaaagatag gtgtttatca tggaaaatat catgcaaaaa gaaatattag ctaagtcata
     4501 caatttaaga actaatcaac aagagcaaac attagttgaa catattaagg atttatttga
     4561 agtattagaa tctatattag aactaaatct atattcagat aaagatgtag agatattgaa
     4621 aatatgttgt gctttgcacg atttaggaaa aattaattcg attatgcaac aaaaaatgga
     4681 gattaataat aaaatatcgt atagttgttc agaagaagag aggaaaaagt tagagtctga
     4741 caaaaaatct ttaaaaaaga tagcaagaca caatatattt tctggagcat ttttaaaaga
     4801 tatattagaa aaaatgaact tgtcagaaga agataagtta tatatatata aaagtataat
     4861 gttacatcat ggaaactatg aagattatat gaggttaagt actagtaaag ttcaagaaga
     4921 aatttatgag tatattgaaa aaggcatttt agaaaaagaa gagtttaatc tgaaagatat
     4981 agaaagttat ataaatgaca ttttaaatgt agattttaaa tttggtgaag atgtattgga
     5041 ttatgattac atagataaat taagtgaaag tatgtttata gacagtgatt ataacaatgg
     5101 tcaaatagaa gattcagttt taaattatag aaagtttaag tatattttat ataaagggat
     5161 gttgaattta atagaccata gtgcatcaag tagacagaaa ggtataaaat tttataacga
     5221 ttttactgat gaagaaattg ataatatgat tttagatgag atatataaga gtcagggtaa
     5281 tttagaaaaa aataatatag agttcaatac tatacaaaaa aggttgagag aactttctgg
     5341 aagaaatgtt ctgactgttg catttacagg ttcaggaaaa accgctgcag attatagaaa
     5401 gacttttaaa agaaaattct ttttagtacc aaataaaata tcagcagaaa gtttttatag
     5461 aaaaaatatt tttcaaaata aaaatgattt aaatacaaga aatagtaatg attatattgg
     5521 attacttcat ggagatataa acttatactc agagaatgaa gataatggag aacatgattt
     5581 tgtattgaca ttaagggata tagatttgag tataaacttt tgtaaacctt gtgtaattgc
     5641 aacagttgac cagttattac ttagtatgtt taaatttccg ggatatgaaa aaatatttgc
     5701 agctgtaaag aatgcatcta taactgttga tgaggtacat ttattagaac caaagatgtt
     5761 tttgattttg atatatttta tgcagtttgc atgcaagtat ttagatgttg attttcattt
     5821 aatgacagct acacttccaa aatcatataa agagcaaatg ataaacaagg gaattatttt
     5881 tcaagaagaa agtaatgaaa atgttactga taaaggagaa atagcgttta ttgagagcaa
     5941 caaggaagaa aacatttgtg aaggtaaaga tgtaaaggtt tcttttataa aggaaaaaga
     6001 aatcaagtca atagttgaag gtgctttaga aaataaacaa aagattctta taataaagaa
     6061 tactattgat tcagtaaata gaacatatga gtttttaaaa gaaaatttat cagataagta
     6121 tagtggtgta gatattgatg ttttgcatag tagatttaaa ttcaaagata aaaaagagaa
     6181 atatagtaaa atattaaatg gaaagggtga tatttggata tcaactcaat cagtagaaat
     6241 atccttggat ttggatttca atataataat aagtgattta gcaactatgg atagtttgat
     6301 acaaagaatg ggtagatgca atagaaataa taaatatgaa tatggaaact tttatattct
     6361 acctagtgaa gataaaattt atgataacaa acttaagaac acaactaaaa gcatcttaaa
     6421 taacgtaata aaaactaact ctatttttac aatggggatt agaaaaacta ttttggatga
     6481 ttactatgat aatagtgtag tcaaaaaata ttttgaagat aattttataa gttgtgataa
     6541 agaaattaag aatatttatg gtataaataa agaaattttt gatggattgg atttaatttt
     6601 taattttgaa ccttataaaa atattgttga tagtaagaag gaagcagcta aaatttttag
     6661 agatgttgat gttagttaca aaattatttt ggaagaagat ttttataagg aagataggga
     6721 gttacaacaa gattcgattc aagtatcagg gtttatattt aatagattat attattatag
     6781 attaataagc aaagtagaag gatacatggt actaaaatct agtagtaagt ttgagtataa
     6841 tagtactgta ggcttaattt taaagtgagc atatgtttaa atataatatg cctttataca
     6901 ttggaaatac aaagagcact aatgtaagcc cactgtaaaa actagttttt taaaagaaaa
     6961 ataagttgtg caatagagtg ttcacacgtg tatatatagc aaatttgggg tttaagatta
     7021 actaagtgga tttcaggtac atcatgaaaa taattataac ctggagattt tgtatgttta
     7081 atattaacta agtagatttc aaatattgat atagtagata taatagaaat tttatgatta
     7141 ggtttaaaat tagctaatcg aattttctaa tattctgact attatataag tatattatta
     7201 tcttgaattt aaaaccaata atataaaaca acaaaatatt atatttatga tataataaaa
     7261 gttatggaaa aataggaaga gtactataga gaagagaggt aaacttatga ataattggat
     7321 agaagtaact ataaaaacaa caacagaagc agttgagcct ataacgaata tactatatga
     7381 acaaggagct ggaggagctg taatagaaga cccaaaagat tttttattcc aaaagaaaaa
     7441 tgaactagat tgggattatg ttgaagaaga agtatttaaa aagaatgaag aagatgatgt
     7501 tcttataaaa acttacgttt ctgaagaaaa aaacgtgatg gaatttgtcg aaataataaa
     7561 gcaaaaagtt ttaggcttaa aagattttgg tatagatata ggtgaaggaa gtgtatcatt
     7621 agaccaagta aatgaagctg attgggcaaa tgcatggaaa gcatactaca aaccaacaaa
     7681 agtaggacaa agggtagtag taaaacctac atgggaagat tatgctatgc aagatgggga
     7741 tttaatcata gagcttgacc ctggaatggc atttggtaca ggtacacatg agactactag
     7801 tatgtgcatt agagaattag aaaagtatgt taataaagat tctaaagtat ttgatattgg
     7861 ctgtggtagt ggaatccttg caatagcagc agccaaatta ggagcaaaag aagttgtagc
     7921 tgtagattta gatgaagtgg ctgtaaaagt tgcaaaagaa aatgttcttg aaaataaagt
     7981 tgaaaaaagt gtatctgtaa tgcatggtaa tttaactgat gtaataaaag ataaagcgga
     8041 tgtaatagtt gcaaatataa tagctgatat aataaagata cttgcaaaag atgttcaaaa
     8101 ttttatgaaa gaagatgcta tatttatatc ttcaggtata attttggata aagtagaaga
     8161 agtaaaagaa agtttaattg aaaatggatt tgaaatagtt gaagttcaaa aattaggtga
     8221 atggtcagca atagtttcta agcttaaaaa ttaagggata tggtgacgta taatggatag
     8281 attctttgtt gaaaaaaata atataaatct acaagataaa acttgcacta tagaaggtga
     8341 agatgtaaaa catatttcaa aagttttaag atataagcca ggtgagaaac ttgagatatg
     8401 tgacaagaat aataatgagt atatttgtga gatagtgaat atagataaga gtatagttaa
     8461 cttaaatatt ttagaaaaag tcgatataaa tagggaatca gaacttaaaa taaggttata
     8521 tcagggactt ccaaaagctc caaaaatgga gatgatactt caaaaattaa ctgaagtagg
     8581 tgtagaagaa ataatattag ttcaaactaa gagaagtgtt gctaaagttg atgacaaaaa
     8641 agaagataaa aaatttgaac gttgggaaag aataatttat gaagcagcaa agcaaagtaa
     8701 aagaggtaag ataccaaaat taagaggtgt tttaactttt aaagaagctt tagaagatat
     8761 gaaaaaaaat aatataaata tttgtcctta tgaaaacgaa agaacagttc caatgaaaca
     8821 tgcactacaa aattgtgact ctaatataga tagtgttgga atttttatag gtccagaagg
     8881 tggattttct gaagaagaaa tagaacaaat acaaaagaat aattgcaatg ttgtatcact
     8941 aggacctaga atactaagaa ctgagacagc ttctgttgta gcatcaacaa tagctttgta
     9001 tgagctaagt gatttaggag gagaaaaata aattgaaaaa agtagctttt tatacacttg
     9061 gatgtaaagt caatcaatat gaaacagaag ctatgctaga actatttgaa aaagatggct
     9121 atgaacaagt caatagtgaa gagtatgctg atgtttatgt tataaataca tgtacagtta
     9181 ctcatatgag tgatagaaaa tctcgtcagt acataagacg agttaaaaag aagaacccag
     9241 acgcaataat agctgttgta ggatgctatt ctcaggtatc tccagaagaa attttggata
     9301 tagaagaagt aaatttagtc atgggtacaa atgatagaag aaagattgtt gaagaaatta
     9361 aaaagataaa ttcaagtaag aaagttagta cagttgatga tataatgaaa gttaaagctt
     9421 ttgaagaaat agaaatcagc caaactaatg gaaaaactag agcatttatg aaaatacaag
     9481 atggatgtga cagattttgt acttattgta tcattcctta tgcccgagga cgcgttagaa
     9541 gtagagatat tgatagtata gtcgatgaag tgaaaaaatt ggctaataat ggctataaag
     9601 aggtcgtatt aacaggaata catgttgctt cttatggaaa agatttaaag gatagggata
     9661 ttaaacttct tgatgtaata aaacaaataa acaagataga aaaaatagaa agaattaggc
     9721 ttagttctgt tgaaccaatt ttatttacag atgaatttgt aaatgaagtt ttaaagatgg
     9781 ataaagtttg tcctcattac catttgtcac ttcaaagtgg atgtgatgaa actttaaaaa
     9841 gaatgaatag aagatacaca actctagagt acaaaactat tgtagataga ttgagaagta
     9901 aaatgccaga tgttgcaata actacagatg taatagtagg tttccctgga gagacaaatg
     9961 aagagtttaa aaaaacgtac gagtttttaa aagaaataga gctttcacaa atgcatattt
    10021 ttaaatattc accaagaaaa ggaactccag ctgcaactat ggaaaatcaa gttgaccctc
    10081 aaatgaaaca ttttagaagc gaacaacttt taaatttgag taaagtaaat tttaataaat
    10141 ttgcaactaa atttatcggc cgtaagttgg atgttttatt tgaacaaaat ctagaaggca
    10201 ataaatatga gggattaact tcaaattata taagagttgt tgttgaaagt gacaaaaata
    10261 tacaaggtca gatattaaaa gtgaaaataa atgatgtaaa agatgaatat gtagaaggaa
    10321 ttttgctata acatgtagaa attataatat ttataagata ggaggtggaa agaatggatt
    10381 gtattttttg taaaatagcg aacggagaaa taccttcaac taaagtttat gaagatgata
    10441 gagtcttagc ctttaatgac ttgaacccag ttgctccata tcatatatta gttgtaccta
    10501 aaaaacatta tgatagttta attgatatta ctgataaaga gatggacatt gtgtcacata
    10561 ttcatgttgt tattaataaa atagctaaag agaaaggttt tgaccaaact ggattcagag
    10621 tcataaataa ttgtggaagt gatggagggc aagaagttaa acatttgcac tatcatattt
    10681 tagctggtaa aaagcttcct aattacgaag cgggacaaaa ctaaactaaa ttattgaaaa
    10741 attgagttcc ttcttgataa aaatacttga taaaagtaaa aatttagttt ataataaaca
    10801 aagtgttagg ttgtaatgca tattatgcaa aaagaacata gttacagtcc cagcataatt
    10861 gcgctattgg agggagggaa aaagaaatgt cagaagtaag agttagagag aatgaaacat
    10921 tagacagcgc tttaagaaga ttcaagcgtc aatgtgcaat gtctggcatc atgtcagaag
    10981 tgagaaaaag agagcactat gataagccaa gcgttaagcg taagaaaaaa gctgaagcag
    11041 caagaagaaa aaacgctaag aaatagtagt aaataagaat aaagaggtga aggggatgtc
    11101 ccttaagcaa aagttacaag aggatttgaa atcttcgatg aaaaacaaag atacagtgag
    11161 aaaatctgta gtaactttaa taagagcttc tataaagcag tatgaggttg ataatagggt
    11221 cgagcttgat gaagatggaa ttatcgatgt aatagcaaaa caattaaagc aacgtagaga
    11281 tgcattagtt gaatttgaaa aagctggaag agaagactta ataaaagaaa cagaaggtga
    11341 aattgaagtt ttaaaagagt acctacctca acaattaagc gaagaagagt tagaagaaat
    11401 tgtaaaatct actatatctg aagtaggggc aacttctatg aaggatatgg gaaaaataat
    11461 gtcagttatc caaccaaaag ttaaaggaag agctgacgga aaacttataa ataagttggt
    11521 aaaacaaaac ttacaataga ttgatatagc ctagagagaa atctctaggc tttttataat
    11581 ttttgggaat aacgagtcat atttgagcat atctataatc aaagaaaatt ttgaaagaag
    11641 gggaaaaatt tgattatatc agtaaaagag attaggaatt ttttgataaa catatttata
    11701 ccactaataa taggttactt aagtagcatt ttaacaatga ttatcagtgg aacagatatt
    11761 tcaacctatt atttacagct cacaaagcca agctttgcac caccagcttt tatatttcct
    11821 atagtttgga ctatattgta catattgatg ggtatatctt catacctaat attaagaaag
    11881 ggttacaact tacctaaagt aagagatgca attttttatt atggattaca acttgtatta
    11941 aactttattt ggagtatact attttttgga tttggactta gatttacagc tttgatagat
    12001 ataataataa tgattttggt ttctataata atgatttcga agttttctaa aatagataag
    12061 agatctggat acataaattt ggtttattta atgtggcttg tttatgcagg atttttgaac
    12121 tattttatat ggtttattaa taaatagaat gtaaagattt tgtaaattac cctgtacttt
    12181 taataatatc ataacaaacg aaaaataaat agactattaa aaataatcat tttcatatac
    12241 aataatatta atttaaatat aataaattta taaaaattgt atttaaagat taacatatta
    12301 aagtattaga attggaaagg cttgaaggga gaggttttta tgcaaataat agtatctggg
    12361 agacaaatga aattaactga cggaataaaa ggatacgtag atggaaaatt aagtaggtta
    12421 gaaaaatacc ttgatcctga atcagaagtg aaagtaacag taagtgcgaa aaaggataga
    12481 caaaaagtgg aagttacaat aattcctatc aatggtcaaa taataagagc agaagacgta
    12541 gaagatgact tatatgcagc aattgatatt gtttgtgaca aattaagtag acaagttgtc
    12601 aaatataaaa ctaaagttaa agataaagtt caaaataata agagcataag atttgaaaat
    12661 gttgacttta tagataatag cagtgaattt gatgattatg atgatgaaga atatgaaaat
    12721 atagttatag aaagaagaaa gaaatttaat gtaaaaccta tgagttctga agaggctata
    12781 cttcaaatgg aactagtagg acacaatttc tatatgttta gaaatcaaga taattttgaa
    12841 ataaacatag tgtataaacg taaagctggt ggatatggtt taatagaaca agactaataa
    12901 aaaattgtat acgtttagat tttatataag aaaaaataaa gaggtaatca tgttgatttt
    12961 ttatcaatat gattaccttt ttattgttca aataatatat tagatattag gtgtttatta
    13021 tataaaaatt ttaaaactaa tctgttacaa catcaataaa gtgcataaat acctatttca
    13081 agcataaaat taattaaggg ggtaatgctt atgttagaaa tatccactga tttacaagta
    13141 aatcaaccag ttattactgt tacaagtaat acgtttatta gtatagaaaa ttatctatca
    13201 atattagaat atgaagttga tttaataaga ataaagacta aggttaaaac aattaaaata
    13261 tctggggata aactttcact taaatatatt actgatagtg agataggtat aaaagggatt
    13321 atctacaatg ttgagtatgt tgattaggag gagatacact tgataagttt tataagggga
    13381 tactatgtta tagttgtgga aggagtagga ctcgaacaat ttttaaatca tcttataaga
    13441 aatggtataa gtgtttacaa tgtaactaga ataaaaaata ctaaaatgga gtttcatata
    13501 gatagacaag atataaaaga atttaagaat gtttatagag gtagtaagtt tgatataaag
    13561 gtaaagcaaa aaactggggt tccttttatt atcaaaagag tttataagca caaaggtatg
    13621 tggatttgtg ctcttgtatc gttattttta ttgatgtcga catcacagtt tgtgacagat
    13681 gtatatatac aatctcctga aggtataaaa aaagaagctc ttagaagtga gctttataag
    13741 gttggagtaa gaccaggagt ctataagaag agtattgata gaaaagaagt tagagaccat
    13801 atgatgtcga aatttaatga tgtggcatat ttatctatca atgtgaaagg aacaaatata
    13861 tttgttactg ttacaaaaaa ggcagaatcc ctaaaatcta cagaccaatc aaattattgt
    13921 aatgtaattg ctttaaaaaa tggtataata gaaaaggtaa tccctagaag tggtaaatca
    13981 gttattaaat ctggagatat agtccaaaag ggagatgtct tgttaaatgg agctaatacc
    14041 aagtcaatac cagaagtatg ggcaagtact ttttatgagt ccacaaaaaa ggcaagttat
    14101 gtagatactg taaataaaaa aactggagaa aagaaaaata tatatacact aagtttttat
    14161 gataaagagt ttacaatgag aaaaaatata aaatataaag attatgttgt tgaaaataaa
    14221 gaaaaaaaac tatcaatagg aaactatact tttccaataa agataaaaac gagcactttt
    14281 tatgaaacaa aaaaggttga agtaaaaagg aataaagaag agttaaaaaa agaattatct
    14341 gaaaaagctt taaaagagtt agaatacata attccagctt cggctagaat aatagatgta
    14401 aaacataact ttaaggttaa taaaaatatg ttagaatatt taataaccgt tcaaactagt
    14461 gaaaatattg ctaaaattta tcctcttagt aaatcagaag cagaaaggtt tataaaggaa
    14521 gaaagtaaac cagatgaagg tgaagaggaa attccttcca atccagaaaa aagaccatta
    14581 aatgatataa gaaatgagtt tgatgaggat aataaggata acaaagaaca aaacaattct
    14641 gatgaaaata atagtaatca aaatagtaat agcaataaca actaataaaa ttaaacttaa
    14701 aatcttagga ggaataattc aattgataat acaaaagaaa tttacaatag cagatggtaa
    14761 ctttgaaaga gagttatttg gcaactttga tgaaaatgta aaattaatag agaagacttt
    14821 aaatatagat gtaatactta gagaaggtaa tataatttta attggagaag aaaaaaatgt
    14881 agattctgca ttaaagctta tgaatgaatt acaccagact gtatcaaatg gtaagcattt
    14941 agataaacag agtatttctt attcattatc tcttttactt gaaggtagtg aacaaaaaat
    15001 aaaagaactt gaggggacaa tcgttataac tcaaagaggt aaagctgttc aacctaaaac
    15061 tttaggtcaa aaagaatata taaaacttat agaaaataat gatataactt ttggcgttgg
    15121 acctgctgga acaggaaaga cttatcttgc tgttgctatg gcagtaaaag cttttaaaag
    15181 agatgaagta agtagaatta tacttacaag accagctgtg gaagcaggag agagtctagg
    15241 ttttttacca ggagatttaa aggacaaagt tgacccatac ttaagaccac tatatgatgc
    15301 cttatttgaa atgctgggtg ctgataaatt caataagtat ctagaaagag gtactattga
    15361 ggttgcacca cttgcattta tgagaggtag aacacttgat aattcattta taatattaga
    15421 tgaagctcaa aataccactt ctgaacaaat gaaaatgttt ttaactagac taggatttgg
    15481 ttctaaagct gtagttacag gtgatgtaac tcaaacagat ttaccacaaa ataagaagag
    15541 tggtctaata caagctacag agattcttaa aggtgttcca ggtattgggt ctataatgct
    15601 aacagataga gatgttgtaa gacatgagct ggtacagaga ataataagag cttatgagaa
    15661 gcacgacaaa agagaagaat ttaaaaaaga agagcgtaaa aaagcgaaaa tgcaggaaaa
    15721 gactttcaaa agaaagtaaa agtgtagtaa tatagatata tagcattatt aatgaataaa
    15781 aagtaggtgt agtgaatgga tttgatacta gatgatagac aagataaatt agaagtaagt
    15841 gaggagttac ttgaaaagat aaaggatata atcctagaat gtttagatta tgaaggatat
    15901 gatgataatt atgaagtgag tctttctttt gtagataata aagagattca tgaattaaat
    15961 agagaatata gaggagttga tagagtaact gatgttttat catttcctct tttaagtgat
    16021 gattttgaag atgttgagtt agaagaagaa tcattaggcg atatagtagt atctcttgaa
    16081 agagccttag aacagagtat agagtataac catagttttg aaagggaagt atgtttttta
    16141 atatgtcata gtatgtttca tcttttagga tatgaccacg atacagatga aaatacaaaa
    16201 gaaatgagag aaaaagaaga acacatatta aataagttaa acataacaag ggagtagttt
    16261 ttatgaaacc agaaaaaact cgtcaaggta taattaaagc gtttaatgca gctatagaag
    16321 ggatattgta tacatttaaa tttgaaagaa atatgaaaat acattattta ggttcagttg
    16381 ctgttcttat aataagtttg ttttttaact tttcaaaatt agaaatgata atgttgctta
    16441 tgtccatatg tttagttgta gttgcggaga tgtttaatac agctatagaa aaagctgttg
    16501 atttagtaac tgatgaatat catgttcttg ctaagatagc aaaagatgtt gcagctggag
    16561 gtgttctagt agcagcacta aattcagtag tagttggata tattttgttt tatgataaat
    16621 tgacagatat atctgggata ttaatttata aaataagaga atcagaatta catataacct
    16681 tgatatgtat attattggtt cttatagctg ttgtagttgt aaaagcattg acttctacag
    16741 gtactccctt aaaaggagga atgccaagtg gtcatgctgc attagcattt gctatagcaa
    16801 ctgcaattac acttatgact gaaagggttg ttgcatctac tcttgcatat ataatggctg
    16861 tgttagttgc ccaaagtaga attgaaggaa aaatacatac cttttgggag actatcgctg
    16921 gagctttatt aggtgtgttg atagctatat tagtatttca gcttggaatg ttctataatt
    16981 aaaatgaatg tacataaaat atttaacata aaacaaatct gtgctaatta aatttttatg
    17041 atataatgta gagtattaaa taaaaataac ttttaattat tgtatacagg aggagttgtt
    17101 gtggataaca tagaattgtt aaggttggca gaagatgcca gacaacattc ttatgctcct
    17161 tactcaagct ttagagtagg tgcagctctt ttaactaaga gtggtaaagt ttatactgga
    17221 tgtaatatag aatgtgcatc attaggtgga acaaattgtg cagaaagaac agctattttt
    17281 aaagcgatat cagaaggtga taaggatatc tataaaatag ccatagcaag tgataactca
    17341 gaaaataatg agcaaacata tccatgtgga atatgcaggc aggtaattat agagtttggt
    17401 tctgatataa aaataataac aggatatact aaaggagagg tgtttgaaca tgatataaaa
    17461 gatttgttgc caaactattt ctctggaaat gatttaaaat aaattaaaaa ttataaataa
    17521 atttaagtaa ttaaaacaag aagataaaaa agttaggaga cagttaatgt tcaaatcagg
    17581 ttttgtcagt atagtgggta gaccaaatgt aggaaaatct actttaatga ataatgtagt
    17641 tggagaaaaa atagctataa tgagtgataa acctcaaact acaagaaata caatacaagc
    17701 agtatataca gatgaagaga tgcagatagt gtttttagat acaccgggta ttcacaaacc
    17761 aaaaaataaa ttaggtgaat ttatggtaaa ggcggcaaca gaagccttta aaaatgtaga
    17821 tttaatatta tttgtagttg atgattctaa aaaaataggt cctggagata gaaagataat
    17881 agaggattta agaagtgtta aaacaccaat aattttagtt gtaaacaaaa tagaccaact
    17941 agaccaaaaa gatgagctat ttgatataat caaaatgtat gatagagaag gtatttttaa
    18001 agaaatagta ccaatatcag cattaaaagg aaagaatacg gataccctaa taaaagttat
    18061 acaaaattat ttggaagaag gaccaaagta ctttccagat tatatgatta cagaccagcc
    18121 agaaagagta ttaatagcag aacttataag ggaaaaagtt cttcactatc ttaatgatga
    18181 aatacctcat ggtgtagctg ttgaaattga aaaaatgaaa gcgagaaatg ataaggaaat
    18241 agtagatgta tctgctgtaa tatattgtga aagagattca cataagggga taataatagg
    18301 aaaaaatggt aggaaactaa aaggaatagg taaatcagca agacaagata tagaattact
    18361 tttaggttca caaataaatc ttcaattatg ggttaaagtc aaagaaaatt ggagaaattt
    18421 acaaaattat ataaataatt ttggatataa tgataaataa aggtgggtta tatggatagg
    18481 aaactggatg cttcccaaga tttattatat gaagtaaaat cattaattga taataataaa
    18541 gtattggagt taagagaatt aatagaggaa tatcatataa ttgatatatt cgatataatg
    18601 gaaaatttag aggaagacat gaaaattcaa ttatttgaag tacttccttt agatatggca
    18661 tcttctatat tagaagaagg tagtgtagag ttttttatta gtattttatc taaactggat
    18721 gtagaacact cgaaaaatat acttgaactt atgtctcttg gagatatggc agacaagttg
    18781 agtgaacttg aagaagaaca aagagaacac ataataaatc ttttgaatca agagaatgcc
    18841 gattatgtaa aagagttact cttctatgat gaagattctg ctggtggaac aatgaccact
    18901 ggatatattt ctataaataa agatatgaca gctcttgaag ctatagacca tatgagggaa
    18961 gaagctgaag aagctgaaac tatttattat atatatgtgg ttgatgatga agaaaaacta
    19021 gttggagtat tatcattaag agaattaata gtagctagag atgcaaatat agtagaagat
    19081 ttgatgagtg aaaatataat ttctgtttat gtagatgaag atagagaaga agcagtaaga
    19141 ttggtatcta aatacaattt aatagcaatt ccagtagtag atagacaaga aaaattaaaa
    19201 gggataataa cagtagatga tataattgat gtaatggaag aagaagcaac tgaagatatg
    19261 tataaatttg caggaagttc agaacatgaa agagaagttg ctgaaaaaga aaaccctaca
    19321 ttgaaagagc aaataatatc agcacttaga ggaagattac catggttaat tattacctta
    19381 gttggagggt tgttggcttc gttaatactt tctaacttag actatataat gaaccctgta
    19441 tatgctccat tagtattttt catacctgta gtaattggca tgggtggaaa tattggaact
    19501 caatcatcat ctgttacagt aataacatta tctaataagg atttaaattt tagcaatgtg
    19561 gttagagaag gtattgtagg aattattaca ggtcttttgt gtagtataat aacaggtatt
    19621 gtaatttact ttgttatgag aaagttagac attgtattaa ttgtttcaat atcattattt
    19681 ataaatatgg ttttgggtgc aacaataggt gcgtttatgc ctgttttatt aaaaaaaatg
    19741 gatgcagacc catctacagt ttcatcacca attatatcta cagctcttga tataactggc
    19801 atagcagttt actttataat aacaacagca ttattgtcaa aaattgttta ataactttat
    19861 gtatgattta tcctcttctt actaaaaata taagtataaa tgtaagaagg gggtttttta
    19921 aaaatgaaca atatcagttg ggaagttttt aaaaaaacag gtagtataga tgcatattta
    19981 tatttctgtg attgcaaaaa catacatgaa gaaattgaag aagtaaggga gaaaaaagaa
    20041 gacgatgata atcctgaaca cccaggggat agtacttaag gctataaggt ataaggaaag
    20101 tgacataata cttacactat ttacaagaaa gcttggaaaa gtatctgcaa tagcaaaagg
    20161 agctaaaaaa aataagagct ctttgctttc atcatcacag ttattttctt atagcaattt
    20221 taccttaaaa aaacaaggta atatgtacaa ggttactcaa agtgaaataa taaaaagttt
    20281 ttataatata tcctatgata tagaagcatt ttcttatgct acatatatta caaaattagt
    20341 tgaaaattct atacttgaaa atcagactaa taataggcta tttatattac ttgcacaaac
    20401 tctgtatttg tacacacagg ataatacaga taataggttt ataacagcag cattcgagtt
    20461 aaaattttta gactatatag gatttaaacc tatagtaaat aaatgcatta attgtgaatg
    20521 taaaatttta caaaattctg tgtttaatat ctatgaaggt ggtatactat gtagtaagtg
    20581 tagtaaactt tttgataata atataaaatt agacttaaca actgtaagtc ttatggaata
    20641 tgtattaaga aatgatattt taacatgtag taaagctaaa gtatcaaaat atataacaca
    20701 tgagcttgag aatattctag acaagtattt gaaagtttat gttgataata ttaattttaa
    20761 atcattacac gtattgcaaa gtgtaaaaaa taataaggga gtggataatg atgagtagta
    20821 atataactat tgaaatggtt gattcagtct ttgaaagagt tccaggagca acttatgcag
    20881 aagcaaaaga ggcattagta atgtgcaatg gagatgtaat tgaggcagta atatatttag
    20941 aaaataaaaa aaatacttgt aattgtaaag caaaatctgc taaagaaact atggaagaag
    21001 tatttggtaa agatggagaa aatataaagt tccaattaaa agagcttctt agaaaaagta
    21061 gtgtagtgag aataatagtt gaaaaagatg gaaaaactat gatgaacatt cctttaacag
    21121 ttggagttgt tggattagct tttgtaccat tagctacttt agttggatta tcagctgctg
    21181 ttataagtaa atatcgtata aaagttcaaa atgaagaaga tggagaaatt gtagacttag
    21241 gtgagttgaa tgaagaaaaa cttcatgttt tgaagaatat gataactaat gcagcaaaag
    21301 atgtaaagga tgtagtagtt gacaaaaaag aagatgataa ggatgtaact gctgacctta
    21361 tgaaagaaga atctgaaaag aataaagaag acgaagacga aaataaatag atataaagtg
    21421 acttttaaaa aatgaagaga agataattat aagaattatc gctaacattg acaaatttta
    21481 tagaatttga tattctaaaa gttgtagaag aactattaaa atagcctttc gtgtagacga
    21541 gaggctttat tgttatagga gggattttta tgaattttca agagatgata ctggcgttgc
    21601 aaaaatactg gtcaaagcaa ggttgtatca tgatgcaacc ctatgatatt gaaaaaggtg
    21661 caggaactat gaatcctaat acttttttaa gatcattagg acctgaacct tggcaagtat
    21721 gctatgtaga gccttcaaga agaccagcag atggaagata tggtgaaaac ccaaacagac
    21781 tatatcaaca tcatcagttc caagttatac taaaaccttc tccagataat atacaagagt
    21841 tgtatttgga gagcttaaaa gaaattggga ttgacccaag tgagcatgat ataagatttg
    21901 ttgaagataa ctgggaagct gctacagttg gtgcctgggg acttggatgg gaagtttggc
    21961 tagatggtat ggaaataact caatttacgt attttcaaca agtaggtaat attgaatgtg
    22021 agcttgagac aggagaaatt acatatggat tagaaagatt agctatgtac attcaagaag
    22081 ttgatagtgt ttatgactta aaatggaatg ataaaataac ttatggtgaa gtatttaata
    22141 aagctgagta tgaaaactca atgtatgcat ttgaattatg tgatgcagat atgttgttta
    22201 atctgtttga tatatatgaa aaagaagcat taagacttat ggaaaatgga cttgtaatac
    22261 cttcatatga ctatgtgtta aaatgctctc atgcatttaa tacattggat gcaagaggtg
    22321 caataggagt tagtcaaaga gcttcattta taggtagagt tagaaatatg gcaaagactg
    22381 ttgcagaaac ttttgtaaaa caaagagaag aaatgggatt ccctctttta aaggacggtg
    22441 acaaataatg aaaaattatc ttttatttga aatcggtgtt gaagaaatgc catcaagatt
    22501 tgtaggcagc acactagaac aattaaaaaa caatcttagc aaattatttg atgaaaatag
    22561 aatagctttt gataaaataa atgcgtatgg gacaccaaga agacttactt tagtagtcga
    22621 aggattgagt gatagacaaa gtgatttaga agaggaaata aagggtcctg ctaagaaaat
    22681 tgctgttgat gcagaaaata atttaacaaa accagcatta ggatttataa aaagcaaagg
    22741 attaagtgaa tctgatatat actttaaaca agttggaaaa gatgaatata tctttgctac
    22801 tataaagcaa gatggaaaag aaacttcaga agtactaaaa gatatattac cagatactat
    22861 aaaatctgta gtattcccaa aagctatgcg ttggggagga aaaaatctta agtttgcaag
    22921 acctataaga tggatagtta cattgttaaa tgataaagta ttagagtttg atttagaagg
    22981 aatagtatct tctaatgtaa caaaaggtca tagatttcta ggtgaaagta caatagaagt
    23041 tgattctata gaagactatt ttgaaaaatt agaaaaaaat tatatagttt tagaccaaaa
    23101 taagagaaaa gaaatgataa gaaaacaatg tatagaagtg gcaaattctt taggtggaga
    23161 agttgaattt gatgaagatt tacttgaaga ggtaacttac ttagttgaat atccaactgc
    23221 tttttatgga gaatttgatg tagattatat aaaactacca aaagaagttg ttataactcc
    23281 tatgaaacaa catcaaagat attttccagt acttaaagaa ggaaaactgt tacctaactt
    23341 tatagctgtt agaaatggtg attcttatag aatagacaac gttaaagctg gaaacgaaaa
    23401 agttttagaa gcaagacttg cagatgcttt atttttctat agagaagata ctaagagaaa
    23461 cttagaaagc tatatagaaa aattaaaaac tgttgtattc caagtaaagc taggaactat
    23521 ttatgacaaa actttaagac ttgaaaaatt aagtgctgat atacttgaca gtttaggttt
    23581 agtagatgaa aaggcagata ctataagagc tgctaaatta tctaaggcag atttagttac
    23641 tggaatggta ggagaatttg atgaattaca aggttttatg ggaaaagaat acgcaaaagt
    23701 tggaggagag aacgatgttg taagtgaagc tatttttgag cattatcttc caagatttgc
    23761 aggagatata cttcctaaga ctaacgcagg ggttgcctta tcaatagctg ataagttgga
    23821 ttcaatagta ggtttctttg ctataggaat acaaccaaca ggttctcaag acccatatgc
    23881 tttaagaaga caagctttag gtatacttag tatacttatg gacagaaaag ttgctgtgga
    23941 tataaaagta cttattgaac atgctttaga taattattct gaattagatt ttaatagaga
    24001 agaagttgtt gaacaaataa tgaatttctt caatgagaga gtaaaaaatc tgtttaaaga
    24061 tttaggaata agatatgatg ttgtcgatgc tgttttaagt tctgatataa atgatgtttc
    24121 tgacatgcat atgagagctt tagagcttaa taattggcta gaaaaagatg aattagtgga
    24181 gatgcttact gcatttaaca gagtttctac tttagctcaa aaagcagaaa gcgataaaat
    24241 tgatgaatct ttattaaaag aagatgctga aattaagctt tacaatgaat ttaaacaagt
    24301 aaaggtaaga gttaagcaat tattaaaaga taagaaatat ggtgttgctt tagatgaatt
    24361 tgcatcttta agaccagtag ttgataattt atttgataca gttatggtaa tggataatga
    24421 tgaagctata aagaacaata gacttgcttt acttaaacaa gtatacgata ctatgctaga
    24481 aatttgtgat ttatctaaaa ttgtttataa ataaaattca agctatttat aaataatgag
    24541 gctatctcaa aatagagata agcctctttt ttatttttga aatgataaaa atatatttaa
    24601 ttgcatacaa aaaagagtac ctcatgaact gaaaagttaa ttttgaggca ctgctacttt
    24661 ttataagtaa atgtaataaa tcatatttta tacttatcag ttattttgtt taagatgtca
    24721 tcatttgaat ttacccattc ataaaaattt cctgttgaag cgtcagatat tttataaagc
    24781 atttcaggaa tatcgctagc tttaaaatct ccaagtgatt ttcctaatct agtcttgcct
    24841 atttcaaagc tacctccaac aaataattca aatgcatctg tagatacacc atcaacattc
    24901 ttctttttac cacataaacc tatactacca acttggtgaa caccacatga atttaaacat
    24961 cctgatatat ataacttagg tgctttattt aaaatttctt cattattctg taatctaaaa
    25021 taatctatga tttcatgtaa cattttctga ctattttgta tacccatttg gcaaattgga
    25081 acacctatgc aagatatgct ttgttctaat tgagaattac aactaatagt tttacttatt
    25141 tctaatattc tttttgcttc atttccattt aaatttaaaa tatataatcc ctctgtcatt
    25201 cctagtctaa tcatagggtt ttcaatatta tctaattctt taagtaaagt atttaaatcc
    25261 tttgttaaca aaatacctcc aactggatgt atatacacag tgtataaacc atcttgtttt
    25321 tgaggtatta atctggaatc ttgtatacat attttaactc cagatttaga gtagtctatt
    25381 tcttcaatat tgagttcaag accaccattt tctttttcta atttatagta ttctttaaat
    25441 ttttttaaga atagctcttc accaagtgat tcgaccatat atctaactct agctctgttt
    25501 ttattttcat aattgccata atccataaag aatttaatca taccttcaac acaatataat
    25561 gcatctttcg gctttataag ttcgtcaagc tctaaagcaa ctttgggttg tttacctaga
    25621 cctccaccta agaaaactct gaaatattgt tcatcatttt tcaaagtagc cacaaatcct
    25681 aagtcttgta tactacaatg agcagtatct gtgtaacaat tagaataaga aacttttaat
    25741 tttctaggta gatggtatgt agtagcattt ttgataaaat atttatcagt agcaactgca
    25801 tatggagtaa catcaaaggc ttcactaggg tcaactccag acaatggaga taatccaaca
    25861 tttctaggat aattaccacc accacctcta gtgaatatat cgttttttat tccttctttc
    25921 atgatatcga caatcgaatc tatagataaa tcgtgtaatt gtatagcttg tctagttgtt
    25981 aagtgtatct tatctaagtt gtgtttaata gccatttcat agattttatt gagttgatga
    26041 tgagataaaa ctccagcaga tactctaagt cttatcataa aagatttttt gtctctttga
    26101 gcataaacac cgtatccacc agaaaatccc ttatattgca ttttatttat ttctccattt
    26161 aaaaattttg aagaatattc tttaaaatta ggtatttcat ttaacaatat ttttttaaaa
    26221 ttgtccatta tttcacctca ttattagtct tgtataaaaa tatatc
//
LOCUS       DBGJFK010000051        26219 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.051, whole genome shotgun sequence.
ACCESSION   DBGJFK010000051 DBGJFK010000000
VERSION     DBGJFK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.051"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            132..470
                     /locus_tag="ACOIAP_002464"
     CDS             132..470
                     /locus_tag="ACOIAP_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2639346.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            492..809
                     /locus_tag="ACOIAP_002465"
     CDS             492..809
                     /locus_tag="ACOIAP_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2639347.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVSILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLILQIIDIIKK
                     NKI"
     gene            959..1315
                     /locus_tag="ACOIAP_002466"
     CDS             959..1315
                     /locus_tag="ACOIAP_002466"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639348.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFKYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSLGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKR"
     gene            1352..1639
                     /locus_tag="ACOIAP_002467"
     CDS             1352..1639
                     /locus_tag="ACOIAP_002467"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639349.1"
                     /translation="MYRDIKLDKESIDKIYNRRKIKIEREVNIFEDEDVIINKKVLKF
                     PKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVIILYYIYNL"
     gene            complement(1980..2747)
                     /gene="aroD"
                     /locus_tag="ACOIAP_002468"
     CDS             complement(1980..2747)
                     /gene="aroD"
                     /locus_tag="ACOIAP_002468"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGZ2639350.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKEDIIKEAKELKGVCLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYISDIPLLFTFRSLAEGGEKVISKDYYTTLN
                     KEISSTGLVDLIDVELFMGDEVIDEVINFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQDEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELSSVLNLLHKSIN"
     gene            3508..4140
                     /locus_tag="ACOIAP_002469"
     CDS             3508..4140
                     /locus_tag="ACOIAP_002469"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HGZ2639351.1"
                     /translation="MTIPNSTKVYPRNNDYQTVYLKNVITRENIEVGDYTIYNDFCND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHTLKSKSTYTFPIFYEEW
                     GLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVHIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNNTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDELV"
     gene            complement(4513..5382)
                     /locus_tag="ACOIAP_002470"
     CDS             complement(4513..5382)
                     /locus_tag="ACOIAP_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGZ2639352.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELIELRKLGVKMIYLGLESGSNEVLEDIKKGFNSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGKISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(5478..6335)
                     /locus_tag="ACOIAP_002471"
     CDS             complement(5478..6335)
                     /locus_tag="ACOIAP_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2639353.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKKNNRKFN
                     IKNKIFKGIGILFVLILLSFFIWINKTYEPQKLAKEALISNSKVEVTVKENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVVASNFARDNKLIDGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNLS"
     gene            complement(6550..8568)
                     /locus_tag="ACOIAP_002472"
     CDS             complement(6550..8568)
                     /locus_tag="ACOIAP_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGZ2639354.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYIFSYDLK
                     RAVYVPFGLMYIFMVSIPVGISEFPMRLSALAAGAVIIMIAQFVMNRNRMKNIGDKEL
                     ISICDELLEKISLLKNIINDDSSISKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERINLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEVNYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKI
                     KSRDEKKAERKSNIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIDMYKGIVKNIIDEVNKSIENVADVYYIKNLLLVPSLIEDRIMLINAI
                     YKDKYQEDFLENQKLLISNMYNLYINVNKNKIQDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKTLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEVA"
     gene            complement(8840..9616)
                     /locus_tag="ACOIAP_002473"
     CDS             complement(8840..9616)
                     /locus_tag="ACOIAP_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGZ2639355.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALILGLIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     VLCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSIANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(9673..10644)
                     /gene="asrC"
                     /locus_tag="ACOIAP_002474"
     CDS             complement(9673..10644)
                     /gene="asrC"
                     /locus_tag="ACOIAP_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HGZ2639356.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLTIVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTKFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDGDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDENSIIKIILNTYKYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGVKYL"
     gene            complement(10657..11448)
                     /gene="asrB"
                     /locus_tag="ACOIAP_002475"
     CDS             complement(10657..11448)
                     /gene="asrB"
                     /locus_tag="ACOIAP_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HGZ2639357.1"
                     /translation="MNPYIPVNAKILDIVKHTDKEWTFRVNCDTKGVLPGKFYEISIP
                     KYGESPISVSGYGENYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIAGFKSPKDVLFADDLKRWSKKLDI
                     LVTVDGADEGYSGNIGLVTKYIPELDIKNINNTSIVVVGPPMMMKFTVGEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDNTYICLDGPVFDYSYAKNLID"
     gene            complement(11449..12456)
                     /gene="asrA"
                     /locus_tag="ACOIAP_002476"
     CDS             complement(11449..12456)
                     /gene="asrA"
                     /locus_tag="ACOIAP_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HGZ2639358.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVSIPFKGTFSDTDVIRYK
                     EVNSFEEMEFTKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIREKVKFVLVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEIFNGETTEFNIDYVTDNLISVDVPENIDSNEMIRNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVTSKEE
                     I"
     gene            complement(12847..13536)
                     /locus_tag="ACOIAP_002477"
     CDS             complement(12847..13536)
                     /locus_tag="ACOIAP_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGZ2639359.1"
                     /translation="MSKLKDYNIDKVMIFNKLSTKTKNQLKEKAKLKRLQKKEILFYE
                     KDSLDSVYMLLEGKVSIFKISENGERKVIFILNSGEVINDITFDSSKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQSDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(13599..14447)
                     /locus_tag="ACOIAP_002478"
     CDS             complement(13599..14447)
                     /locus_tag="ACOIAP_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGZ2639360.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(14466..15353)
                     /locus_tag="ACOIAP_002479"
     CDS             complement(14466..15353)
                     /locus_tag="ACOIAP_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGZ2639361.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGLIIDKSSLDTEAKEKGGEGIL
                     SKIKGIVKKYIKENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEIEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNINGSSFQELASTSSLIKKVAKIKNLNENELNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(15411..16214)
                     /locus_tag="ACOIAP_002480"
     CDS             complement(15411..16214)
                     /locus_tag="ACOIAP_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HGZ2639362.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESVIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NAGCATLSKHYNIENKYVIWIQGESDAKYGSDALYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACNECDILCVGSKIAMQFHDKGLTIDDVHYTQE
                     GLNILGKDLCKNIYKYHTTKEKELLSDTIDLSEARRYIYELEKISKKFV"
     gene            complement(16374..16826)
                     /locus_tag="ACOIAP_002481"
     CDS             complement(16374..16826)
                     /locus_tag="ACOIAP_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGZ2639363.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEEGDFL
                     PLDGKNNGYVELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(16956..18458)
                     /locus_tag="ACOIAP_002482"
     CDS             complement(16956..18458)
                     /locus_tag="ACOIAP_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HGZ2639364.1"
                     /translation="MVGFTWIDFTILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIVVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YCMPEVTSWAYSLITITTSVVVGTIFSAIEAKVKAKVSLPRAETTVYYEK"
     gene            complement(18491..19372)
                     /locus_tag="ACOIAP_002483"
     CDS             complement(18491..19372)
                     /locus_tag="ACOIAP_002483"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008747 - N-acetylneuraminate lyase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HGZ2639365.1"
                     /translation="MRTTDMKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGL
                     YVGGSTGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGY
                     DAISAVTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENE
                     KIIGVKFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRA
                     RQIFELTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKE
                     ATDEMKSRAKEIYRKYF"
     gene            complement(19442..20113)
                     /locus_tag="ACOIAP_002484"
     CDS             complement(19442..20113)
                     /locus_tag="ACOIAP_002484"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGZ2639366.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCISTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKRVFELGVYSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(20389..20880)
                     /locus_tag="ACOIAP_002485"
     CDS             complement(20389..20880)
                     /locus_tag="ACOIAP_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HGZ2639367.1"
                     /translation="MEGNINNKVDDKFSKVKKKFGNGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSIDDNSFDKFCDELLELDKLIYEKNMEINEMEMVESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIVCGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            complement(20902..22266)
                     /locus_tag="ACOIAP_002486"
     CDS             complement(20902..22266)
                     /locus_tag="ACOIAP_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HGZ2639368.1"
                     /translation="MGEKKINNMNYSHNNYSKTTGEPTRKIKNSHITLKNKEEKICSS
                     CNKENNTKDNYCKFCGNELYEITSLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKSVLANSIGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIKTFIL
                     GYVLVLIILFVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIKPIVVFSIYY
                     AFLMGMLALFSTFILDSNINFFNTTSYGATLIMQFKVLQAIVISFIYSFVISLIGYKL
                     NSAD"
     gene            22685..23860
                     /locus_tag="ACOIAP_002487"
     CDS             22685..23860
                     /locus_tag="ACOIAP_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HGZ2639369.1"
                     /translation="MNLEKIKKFWGFPLDKKHKENVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFATPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKLGESVIVFGGCFLF
                     LNFFLPGIQTIPGNEFSNIVNTFFITSLAVFVSTMLYRSRVFTYYDKLLISQQYEEIY
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCDEEDAKLKSECLRKII
                     ETCNFERDDIPLKCVTVSIGVYTNKIERTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(24033..25430)
                     /gene="asnS"
                     /locus_tag="ACOIAP_002488"
     CDS             complement(24033..25430)
                     /gene="asnS"
                     /locus_tag="ACOIAP_002488"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGZ2639370.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFVRITYTKAVELLIESGHDFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(25507..25740)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(25898..26092)
                     /locus_tag="ACOIAP_002489"
     CDS             complement(25898..26092)
                     /locus_tag="ACOIAP_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HGZ2639371.1"
                     /translation="MENKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVTEAKDWVDNGSKL"
BASE COUNT         8924 a         4339 c         2625 g        10331 t
ORIGIN      
        1 actatacaaa aataaatagc acttatttca gtataaaaac atatatagtc tatatttaaa
       61 ctaaaaaagt ataaatagtc tatataaaac aacttaaact atgaatataa tctaaggtgg
      121 agggataata attggcaaat ataggaaaaa taataggaga tagaataaaa gtctatagaa
      181 caaaattggg atatagtcaa gagtttctag cagaaaaggc aggtttacat ccaacatata
      241 ttggtcagat tgaaagagct gagacaaata catctatcaa tattataatg aaaattgcta
      301 ctgctttaga cataccactt gaattgttat ttgcaaatat tattacaaca gaaggcgttg
      361 ataactctgt acctttagaa tgttatgaaa tgattaataa actaactgaa aaagaacaaa
      421 ttgcaatgct agagttaata aagtgcatca ttaaatacaa agaaatataa gcgagggaaa
      481 tagtaacaat aatgaattat ataggtaaaa gacttaaaga agaacggaaa aaagcaaatt
      541 taacttcaaa agaatttgca aatatggttg gagtatcgcc ttggtatata actcaaatcg
      601 aaagtggtaa aaagaatcca agtcttaaaa cattcataaa atttgtaagt atattaaata
      661 tctctgcaga tgttcttata aaagatatta cttccactgg aaagacatat ttagaaaatg
      721 atataaatga agagttaaaa gacttaaatt caagagaact aaatctgata ttacagatta
      781 tagacatcat aaaaaagaat aaaatataat tctttatatt ttatataaaa aaaaaggtta
      841 tttgaaataa ataacctttt tttgtctttt tgtgttaaca ttgtcttata gtgctaatga
      901 gtactattag accatgttct atggccttat tttaatataa aacgattgga gataggctat
      961 gattgtgatt gaaggtagcg ataaatttaa aattgcaaaa gaatatattg atgtagaata
     1021 tactcttttt agcaaagtaa cttttaagta tgaaaagtta aaatttaaag ataatgctga
     1081 attagaaaaa attaaaatgt ttaaatataa aaatggctac atccctaata aattaaacct
     1141 ttctttagga tatggattct cttcttataa aaaacaaata attagagaaa ctgtagatac
     1201 tttaagattg acagaaattt tttcaagcga gaacatagaa gatattaaat ttataaaaga
     1261 tggtacaaaa aaattagaaa ttagcataga gaaagttgtg aaatttaaac gttgaaaaaa
     1321 aagaaattat gtttgttgct attgccctga tatgtataga gacataaaac tcgacaaaga
     1381 atctatcgat aaaatataca acagaagaaa aataaaaata gaaagagaag ttaatatttt
     1441 tgaagatgag gatgttataa taaacaaaaa agtattgaaa tttccaaaat cttggacaaa
     1501 gaatatgcaa aaatattggc taagtgaaaa taagtatccc atacattcta ctgtaattga
     1561 tgatgataga tataaatgtt gtaatgtaca atatacaaag aatagagtga taatattata
     1621 ttacatatat aacctttaat atacataatt acaaaaaagt aattacaaat acacataata
     1681 caaatatatc ttctacttta gataaaacag ttattataaa aacttactat ctataaataa
     1741 tagaaatgct agtataccat ctataatcca atgtctagta ggttttaatg gcatatttta
     1801 aatatgccat agttgattta taagattttt ataccacttt caaaatacac actaaatagt
     1861 tgcttttcag atattacact taattaacca atttaaattt tactatctga aaagtttttt
     1921 atatttaatt tatatatctt caaaaataac tcctaatatt tctatataat tatattaaat
     1981 taattaatac tcttatgtaa taaattaagt actgagctta actctttaaa tgatatttga
     2041 cctggtgctg aaacactttt tgcagctcca aaagttaatg cagaaccaaa tatttcccca
     2101 cacaatctgc ttataactcc cattcccgac attgacattg ttattattgg tctatctgca
     2161 taaattttaa acatttcatt tgtagcttca agtagaacta acacatcttt ttcatcttgt
     2221 ggcataacag ctattttggg taaatctgcg cctaattcct gcattctaca taaacgagat
     2281 acaatttctt ctttttttgg agttttatta aagtcatgat tagatataat tactttcact
     2341 tcttttttat gagcaaaatt aattacttca tctataacct catctcccat aaataactct
     2401 acatctatta aatctactaa acctgtacta gaaatttctt tatttaaagt agtataataa
     2461 tcttttgata ttactttttc tcccccttct gctaaacttc taaatgtgaa taataaaggg
     2521 atatcagata tataacttct taattcatag agaacttcct taacttcttt aatattttct
     2581 acattctcaa aaaaatcaac tcgccactct ataatatcca aacatactcc ttttaattct
     2641 ttagcctctt ttataatatc ttctttattt ttaccgataa tcggtacaca aattttaggt
     2701 ctaccttctc caatagtaat attttttact tgaacttttc ttttcatatt ctcctccata
     2761 atcagaaatt ctatatgatt ttaaattcta ttttctgcat aatttaatta tacattataa
     2821 atgctacaca ttataaaaat actaatttaa aaataatttt tattctaatt cttaaaacaa
     2881 tcccacatat tttagaaaag atactctata atataaaaac acttctttct tatctaaatt
     2941 tattttaaca ttctataatt ttcataacat tacttaagtt ttatctatat aatcaatatt
     3001 attctggatg ataatagaat taatatataa attatagtat aattatatag aaataactcg
     3061 aattttacta cttatgaaga aatttgatat caataaattc aaatcatttg cattacttca
     3121 gagttttggc taaagttaaa caccatacta aacccaaaat agattttaca gctatacttc
     3181 aagagtaatt gattgtaata gtaccatata atcatccttt agcattaagt gacagtgtag
     3241 attaaaagga taacaatgtt aatgttcttt aaattaaaaa ttattttgta tataaaatat
     3301 attaaattat tgcaagcttt attgttttga tatacaatca actaagcata tagcctttat
     3361 aaaatactaa atagttaaaa gtctgttttt aaaaacaaaa tgtataaatt aaaatataga
     3421 tactatcaag gagtgattct gtgaagagat gtattgtaat agtggaatag tcaaaaacat
     3481 aatatatatc aaaggagaga tttaaatatg actattccaa attcaactaa ggtatatcca
     3541 agaaataatg attatcaaac tgtatatctt aaaaatgtaa taacaagaga aaatatagaa
     3601 gttggagatt acacaatata taatgacttt tgtaatgacc caagagattt tgagaaaaac
     3661 aacgtattat atcattaccc tattaacaat gataaattaa taattggtaa gttttgctca
     3721 atagcatgca atgcaaaatt tctaatgact agtggaaatc acacactgaa atcaaaatcc
     3781 acatatacct ttcctatctt ttatgaagaa tggggactcg atatcaatca tataacggat
     3841 gcttgggaca ataaaggtaa tattataatt ggaaatgatg tgtggatagg ctatgattct
     3901 ataattatgt caggtgtaca tattggcgat ggtgcaatta ttggaacaag agcagttgtt
     3961 actaatgatg tcccaccata ttctattgtt ggaggagtac ctgcaaagat tataaaaaaa
     4021 agatttaata ataatacaat ttcaaaatta ttggaaatta aatggtggga ttggccatat
     4081 aaaaaaatcc aatcaaacat taagcatatt caatcaggaa atatagatga attagtttaa
     4141 tcttttataa tttatatata ttaaatttta ctttaataat cctttttata agaatttttt
     4201 caagatttgt atatcatttt aatatatata aatttaatac aatactaaac aaaaataaaa
     4261 agtaaagttg cttaatataa agttacttta ctttttatta tttaaattca tgggtccatt
     4321 ataatatgta aaattctatt aaaccagttc acattttcat cattattgat agcctatata
     4381 tgaacatacc attttgtttt ttaacaaaaa aatcatgcta tattaatagt aaaaaactat
     4441 taatatagca tgattttttg tatctaaaca atctcagtat ttatctataa atatagattg
     4501 atatatcaaa aactacagtc ttctatattc ttctcttttt aacttttggt tacttagata
     4561 gtaatcaatt tcatcaatta gacgttgttt gtcatcaggt aatacacctt ttaaattagc
     4621 ataatttgat gcatgattac ttctaaatac aattttttca ttggcatcta tattctttat
     4681 catctcttta atttcttgta acacagcctt atcctctagt attgtaaact ctcctgcctt
     4741 aagtaaatcg taaagttcag tattaggttc taccattaaa ctaagtacac ctacataatc
     4801 tggtgaaatt tttcctaaca tttttcctgt atcaacggca tgctgatgtg tttttttagt
     4861 tcctccaaga cctgctatta cagtggctga taatttaatc ccactttttt taacttttct
     4921 accaactttt attaattgtt cactattaaa acctttctta atatcttcca atacttcatt
     4981 gcttccactt tcaagcccta aataaatcat tttaacacca agttttctta actctataag
     5041 ctcatcatca gattttttct ctatagattt aggagaacca tacatagtaa ttctttcaca
     5101 ctctggaaaa acttctttta tatataaaat tatgtctctt aatttctcca ttggtattat
     5161 caatgcatct ccatctgcta agaatattct ttctacatgt ttataatatc ttctaaatat
     5221 atcaatttca ttttttatta cttctagtgg ctttatttta aattttttag atttgtacat
     5281 actacaaaac gtacatttgt tgtgagaaca tcctagtgtg acttgtatta taagactata
     5341 agcctcactt ggcggtctgt aaagtggcat atcgtattcc atattaaaat cccccttgta
     5401 ataaaatatt tattctatta tattattaat atttacttta aataataact tataaaatta
     5461 tattttttaa ttttagttta agataaattc tttaaaaatt taatgatact attggcagta
     5521 atattaagtt gtttttcttg acttataata gcatcattat ctcccttttg ttttccatag
     5581 tctccaaatt gtgcatgatt tcctccttca atttcaacat aagttgtatc atcaggaagt
     5641 ttttgttttg attctacaag acttttaaaa ttgactacac catctttgct cccccatata
     5701 gatataactt tttttcctaa ttctttcaac tcatctccca ttggataaga agctaaaaat
     5761 acaactccat caattaattt attatcacgt gcaaaatttg atgctacaac tcctcctaat
     5821 gaatgacctc ctattaccca atgttctatg ttgttgtaag aatccataac tttctgcgcc
     5881 ttattagttc caagtatagc tagattaagt ggcatcttta caattacaac ctcatatcca
     5941 ctttctgcta tttttcttgc aagtggtgca taagattcta tttctacttt agctcctgga
     6001 tacaaaatta aacctttaga aacttttctt ccttttggtg taaatgaaat gttttctttt
     6061 acagttactt caactttact attgctgatt agagcttctt ttgccagttt ttgaggttca
     6121 tatgttttat ttatccatat gaaaaaacta agcaaaatca atacaaatag tatacctatt
     6181 cccttaaata tcttattctt tatgttaaat tttctattat tctttttatc atctttgttt
     6241 tcaacctcat cataaagtaa aggtctttcg agttccatag ttatactaaa tgtatcatat
     6301 ttcttattgc gttttacctt tacatcttta ctcataaatc taacccccat aatatttgaa
     6361 tactattata gtttatccta agtaaattgt tttttcaacc aatgaaaaaa atcaatattt
     6421 taactatttt catataaaat tcataaatat atgttttttg ttttttatat attattttct
     6481 tttaatattt tataaaacaa atagccatat actttatttt aaatatatgg ctattctata
     6541 atttaatatc taagctactt cttttattga aactttagtt atattactta ttctatacat
     6601 ttctttgaca ccatttagag tttgcagtaa gtttagacat attatcttgt ctcctagagt
     6661 tttagtattt acaatactct ctaaaattac gcttcttccc tcatcatact tatctacatt
     6721 gtaatttgaa atataattag tatctctcaa tattttttca acatcttcat cttgtatttt
     6781 atttttatta acatttatat atagattata catattactt attagtaatt tctgattttc
     6841 taaaaaatct tcttgatatt tatctttata tatagcattt atcaacataa ttctatcttc
     6901 aataagtgat ggtaccaata ataaattctt tatatagtaa acatcagcta cattttctat
     6961 agacttattg acttcatcaa ttatattttt aacgattcct ttatacatgt ctatcacatg
     7021 ttgatagcct gttttagcat catatggtaa tataaactta tttactatta atgcaataat
     7081 tgctcctaat gctacatatg aaatcctgct tattgttaaa acatttgggt ctcccataac
     7141 tacagctgaa ccaagagctg aaacagttac acataccatt aattttctat aatcaactac
     7201 ataagagttt atatatcctg ctaaaagaac tattaacgac cttaatgtac tatcttttat
     7261 tattgaaaat aatacaataa atattacagc tcctataaat gtaccttcta ttctttttct
     7321 agacctttgt atacaatttt ctgcgtaagg ttgtgttaat gaaaaaacag ttaacattat
     7381 ccatcttcca tcccttaaat ggaaataatc cataataaaa cccgctacag ctgtagctaa
     7441 agcaatcttt actgcataag aaaatcttat agaatttaaa ttaaagtttt tcttatatat
     7501 tgatagtcgt ttaaattcat gaggtatatt tgattttctt tcagctttct tttcgtctct
     7561 tgattttatt tttttataat ctactaaaaa ctcatataaa ttttctaaaa cactataaat
     7621 ttcttttaaa tttatatttt tagtatcctg agcaataaca taatctctaa atcctaatat
     7681 ctctttatca gttatggtat ctttattttc taaacacatc ttaatatagt ttacttcttt
     7741 tgttgctaca actagaacat ctgatttact atttatgcta ctttcttcta aaatattttt
     7801 tatatcttca tcttcaaatt ctttactatc ctttttgtat ctttctagga ttaaatttat
     7861 tctttctaat gaaaataaaa tattcattat gtctatacct ctaatactta tataaaagtc
     7921 atcttttcta ttatcaaaaa taaccatttt caaattttta gatatagaat ttattctata
     7981 attacagcta tctatttttc tcatactaga tttacttata gaactatcat cattaataat
     8041 attttttaaa agactaattt tttctaataa ttcatcacat atagatatca gttctttatc
     8101 tccaatattt ttcatcctat ttctgttcat aacaaattga gcaatcatta ttataactgc
     8161 tccagcagct aaagccgaca atctcatagg aaattcactt attcctacag gtatacttac
     8221 cataaatata tacattaggc caaaaggtac atatactgct ctttttaagt cataactaaa
     8281 tatataccct attataaata atgctataaa atttaataaa acgcctaaat acatattttg
     8341 tactgcaaaa aatgatagta ttcctaggat tatatttatt gctaaatact ttagtaaatt
     8401 tttaattgga gaaatagtta aatctctttc caatagtgtt agcatagctg ttactatacc
     8461 aacacctata agtgtgtttt tacttccaaa taaatatatg aatatagaaa taaatgctat
     8521 tataaaaata aacaattttg tttttgatat tactagtttc tttgtcatta tatcccccct
     8581 aaaaatttca acaagaccaa ttttatcata tttgttatct tattcaaaat actctttttt
     8641 acggtaggac tttaactttt tttacatttt gaactatata atctatattt aaacgtattt
     8701 tattgcatat atagtttata tattttcgta tgctcccata tattttttct ttcaaatatt
     8761 ttttcaaaaa tataaaaata actctctcaa caatactaaa actgtattta ttaagagagt
     8821 tataatttat acaataaatt taattaagct tttctttacc caatatataa gttccaagac
     8881 ccataaataa agctcctcca acaatatttc caagtgtcac agctactaaa ttataaatag
     8941 ctcctccaat agtaactgta cttattgttg gtgaaaataa tgaaacacta taaattgtca
     9001 tatttgctat actatgctca aaacctgatg ttataaaggc aaataaacat aagaatatca
     9061 taattatttt tgcagtatca ctattagttc taaacgaaca caatactgat acacatacca
     9121 gaatattaca taaaacccct ctaaagaaaa gagctgtaaa tggcatggat gctttactag
     9181 ctgctgtatt tgcaaaaaat tcagctacag gtcctttatc tactagacca gttcctacaa
     9241 atataagacc taaaattaaa gctccaatta aattacctac ccaactgtat gcccatattt
     9301 tagaagtatc ttttatactt acacctttat ttaacatacc agcagacata accatattgt
     9361 ttccagtaaa taactctgtt cctgtcatta taactaaact tagtgctatt gcaaaggata
     9421 accccattac tatcttagtc ataggtgaac ctgcatcagt caaaagtcct ccaatagtaa
     9481 atatcaaaag tatacctatt cctacataaa gtcctgcaaa cgcagaagat accaaatatt
     9541 ttactttact tgtgtttaat aaatttatct tatttatagc tgcattagtt aatttatcca
     9601 aagtttcttt atgcataatt ccctcttcct tctattaaat tttaatttat tcaaatatat
     9661 gttttactca atttatagat atttaactcc actccagtat atgttttcat acattttagt
     9721 tatttctgga agttctacac cttcaagcgc ccatttttta aactccataa atcctgttct
     9781 atcaattata tatcctatat gttcttttcc tcctggtgca tctttatcta tatacttttc
     9841 tacatatttg taagtattaa gtattatctt tattatgcta ttctcatcta cccataaaag
     9901 aaaatcttct gctagtctag ggtttttctt tcctgttcta cccattatag ctaatctata
     9961 gtattttttc tcatctctag tccatgcatt tgttgggcaa tttagtacac attctccaca
    10021 tcctatacat ttatctccat ctcttaccac cttattattt tctgttttta atgctccaac
    10081 agatatttta gaacattttt ttacacacgc tccacaattt acacatctat ctttttcata
    10141 tatgggtaaa gccataccaa taattccaaa atcattcatt ctagctttta tacaatcatt
    10201 tggacagcca gttaaagcca ctttaaaatg taaatcattt ggaaatatag ctttttctat
    10261 tcttttagca aatttagttg tattatattg agcctttgga cagactttat ttcctataca
    10321 tgctgctata tttcttgtac ccgctgctgg ataacctgca tttttctcac tttgatttat
    10381 attcattttt tcaataacag gttgtataat tttatttatt tcttccatat cttccatatt
    10441 tattcctaat atttcaaagc cctgtcttgt agttatgtgt acctgtccat taccatactc
    10501 acttgcaatt ttagaaacta tagttaaact ctcagggtca ataagcccac caggtactct
    10561 aacccttaaa gaagtctcat attttgtttt tgtaatccta taagcatttt tcattacttt
    10621 tttggtattt aaatctctta tcacaaactt cgccccctaa tcaataagat ttttagcata
    10681 tgaataatca aatactggtc catctaaaca tatataagtg ttatccattt tacagtgtcc
    10741 acatttacct ataccacaac acatttttct ttcataagaa acccaaatat tcttttcatc
    10801 taaatctctt tttaaaaatt ctcctactgt aaacttcatc atcattggag gtccaactac
    10861 aactatagaa gtattattta tattttttat atccaattct ggtatgtatt ttgtcactaa
    10921 tcctatattt ccactatatc cttcgtctgc tccatctaca gtaactaaaa tatcaagttt
    10981 tttactccat ctcttcaaat catctgcaaa taaaacatct tttggtgatt taaatcctgc
    11041 tattaattta aacttttcgc atttttcttt attgttgtaa aaatattcaa ctattcctct
    11101 tacaggggct aatgcacttc ctcctgccac tactacaatt tctcttcctt cgtaaagaga
    11161 tacatcaaat ccatttccat aaggccctct tataaaaaaa gaatctcctt ctttataatt
    11221 aaacaactca ctagttactt ttcctacatt tcttattgta aagtcaatat agttctctcc
    11281 atatcctgat actgatattg ggctttcacc gtatttaggt atagatatct cataaaattt
    11341 tccaggcaat acaccttttg tatcgcaatt tactctaaaa gtccattctt tatcagtatg
    11401 cttaactata tctaatattt ttgcgtttac tggtatatat gggttcattt atatttcctc
    11461 cttactagtt actaaatcat ttattttttc tatacatttt gaaaatgata tgtattgtgg
    11521 acaggcatca tcacatcttc cacaaccaac acacatatga tatccgaatc tttttttaaa
    11581 atcatgtatt ttatgcatag ttttaaatct cattctttca ccttgttttt ttctaaaaga
    11641 atttccacct gctatatctg tatatccatc tacttgacaa gaagcccaaa ctcttcttct
    11701 ctcacctaca ttctcatttt ccttatagaa aatatcctgc attgtaaaac atgaacatgt
    11761 tggacataca aaattacatc taccacatcc tatacatctt gtatcatatt catcccatat
    11821 agaatttctt atcatttcat ttgaatcaat attttctggc acatctacag atattaaatt
    11881 atcagttaca taatcaatat taaattcagt cgtttctcca ttaaatattt caaattcact
    11941 atcctttatg tctaaataca gtgtatctcc ttctatattt aatccaattg aataattatc
    12001 agttttgtta gaatccatac tcacacaaaa acagtttcta aaactttcct tacaccctac
    12061 aagtacaaac tttactttct ctctgatatt tttataaaaa taatcttttt cttcgccatt
    12121 atttagatat atttcatcaa gtctttttat cccatttatg tcacaagctc tcaagaaaat
    12181 taaaattttc ttgttgtcta aatcgctttc cttaaactct ttttcagtaa aataaaataa
    12241 tacttgattt ataggaagta caacttcttt tggtgagaaa tttgctttct tggtaaattc
    12301 catttcttca aaagagttta cctccttgta tcttataaca tcagtatctg aaaaagtacc
    12361 tttaaatggt attgaaactg gtgcaaatat cttgtagtct ttttttagat aattcagacc
    12421 ttcattgaat ttagatgaat ctaattttaa tttcattctt atcacctttc ttatatttta
    12481 gttttactta cttcttatct tgtttaaatc ttaacatttt attttctatg cttctgtgat
    12541 aattatcaca gtttcaaaaa taataaaaaa atattaatag agtttattaa gctctattaa
    12601 tattttttta ttatctatat tattcgatta caaatctagt cacttaaata caatcattaa
    12661 atacaataaa tctattatct actcaacttt ttgaataata gagagtctta tttgcttttt
    12721 tatacaattt aggaaaggta aaataaggat taataaatta gacaataaaa aagaatctat
    12781 aaatagattc tcccaataat atttttaatt aattaaaatc ctaataatac ccttatttaa
    12841 tcataactaa ttatttttaa aataccttga taattcagtt tctttaacgt aaaaaccttt
    12901 attatcaatc ttaataagtt cttctttttg taataccttt atcattctag aaacagtctc
    12961 tcttttacag ccaagcatat cagctaaata tgtaactgta atatttacat ttagtaaagt
    13021 ccattctcca cagcaaactc caaattctct acttaaccta tataattttg ctgcgagttt
    13081 tttatctact tttatagata tagaattttt caactgtcta tataaacgtc ttattcttct
    13141 ttccatataa gaaataatat cttttgtaag ttgaaaatca ctttgcataa tttctaaaaa
    13201 ctcttcaata ctataataag ctacaattga gttttcaaat gcttcacagc caacagtgga
    13261 gtttttagaa gagtcaaatg taatatcatt tatgacttct ccactattta atatgaaaat
    13321 tacttttctc tcaccatttt cacttatctt aaaaatagat acctttcctt ctaaaagcat
    13381 ataaacactg tctaagctat ctttttcata aaataaaatt tctttttttt gtaatctttt
    13441 tagtttagct ttttctttaa gttgattctt cgttttggta cttaacttat taaaaatcat
    13501 tactttatca atattataat cttttaattt agacatgtaa tatctctcca ttcctaagtt
    13561 tttaagagag ctctataaaa cattacaaat ttcttatttt attcattttt aaacaatttt
    13621 atagcatttg tagttttaat ttttctttca atagcttcat tagaaagttc ttttactact
    13681 tgtgtatata ctaaatcaat aatgaagaat tgtgctaatt tagaagatat tgaaccggtt
    13741 tccagtactg tttctcctga tacataagat aagtgtacat ctgaaatatc ctttaattca
    13801 gaatttttat tttcagtaat tgatataatt ttagcattat tggctcttgc aagctttaca
    13861 gtttttataa tctcctctgt ttcaccagaa tgtgaaattg caattattaa atctccttct
    13921 tccattatgg aagacatcat tatcatggta tgactactgt caaaacttac acaattaaga
    13981 cctattctca taaatttata gtttgaatcc tgtgctatta taccagaata tccaatacct
    14041 atgaagtaaa ctttctttgc atttattata agccttgcac agtcatgtac atccttacta
    14101 ttgattatct ccactgtgtt ctctaaagtg gttacatttg aacttaaaag tttttttgct
    14161 gtatctaaag ctggctcatc attttgtata tttttattta taatattttt tttattgata
    14221 gttgatattt cttgtgctaa agtaacttta aaatcctgta atccattaaa attcattttt
    14281 tttacaaatc tagttatggt tgcttcacca atattgcttt ctttagctat ttgtgatatt
    14341 ggtttataaa acacatcatc tatattttct tttatataag ctattaataa tttatctgac
    14401 tttgtgactt taaaagttgg tgattccaat tgttctaaaa tactcattaa aaacccttct
    14461 attctttata ttttgtttaa aaaattatat aatgccccaa gcattcccgc atcattttgt
    14521 ctctttgcaa attctatatt agtgtttttg taaactctct ctataagaac ctcctttaat
    14581 gctttgtcta tttttggttt taggaacttt tcttgtgcca taatcccacc acctaaaatt
    14641 actacctctg gatttattac ataacatata tttgcgattc caactgctaa tgattttatc
    14701 atattatcga gttcttttaa acaatcttcg tcattattct ttgctaaatc aaaaattatt
    14761 tttccattta attcattttc attcaaattt tttatttttg ctactttttt aattagactg
    14821 ctagtagatg ccaattcttg aaaagaactt ccatttatat tcatatatcc tacttcgcca
    14881 gcactattac taaacccatt tatcagttta ttgtttatta taatacatcc accaattcca
    14941 gtacctattg ttaaacatat agaagatgtt gcacctctac ctgctccaag ccacatttca
    15001 ccaagtccag cacaattaac atcattttca acttcacatt ttatattaaa ctctttttct
    15061 atttcttttt ttaattgcat acccttatag tttggaatta attcttctaa tgcaaatagt
    15121 attttacctt caactgggtc aaccatacct gcagttgata tgcatatacc acttatttca
    15181 ttttctttta tatacttttt tactatacct tttattttag ataatattcc ttctccacct
    15241 ttttcttttg cttcagtatc aagacttgat ttatcaatta ttaatccatc ttctctaata
    15301 aatccatatt ttattgaagt acctccaaca tctatacaaa cgtaattttt cataacatat
    15361 ctccatataa attattttta taaattgata acactactta aactcttata ttaaacaaat
    15421 tttttactta tcttttccaa ttcatatata taccttcttg cttctgataa atctattgta
    15481 tcgcttaata attctttttc cttagttgta tgatatttat aaatattttt acacaagtct
    15541 tttcctaata tattaagacc ttcttgagtg taatgtacat catcaatagt taacccttta
    15601 tcatgaaatt gcatagcaat tttgcttcct acacataata tatcacattc attacaagca
    15661 gactcctgtg ctgctgcaat tcgtcttgtt ctaataaaat attcatcttc tccaagccaa
    15721 taaccagtta aacttacaaa cattttatca atcatacatt cttctttaag tctataagca
    15781 atctttttta gactttcttt atagtacaat gcatcactac catatttcgc atcactttca
    15841 ccttgaatcc aaataacata tttattttct atattataat gtttacttaa ggtagcacag
    15901 cctgcattaa atttttctat agtgtcattt aggaaccagt tattatcatg attccagttt
    15961 tttattcttg aaccatcttt tgcattgtga ataaaacaaa ctttatttcc agtaagctta
    16021 ttccattcat ttgaaaatgc aggtgctata gtaccatcac cttctgaagt ttctagctca
    16081 catctcatat ttataatttc atcagtactt aaatattcaa aacaattttc atttggaatg
    16141 acactctctt tgggattccc taatcctcta gcattgcttt gtcctattaa taagaataca
    16201 tctatatttt ccataagtta actcctttac aaaattttaa acttttaatt attttcaatt
    16261 tccttataaa aaactaaggc tgaaaatagt aatctaacta aaatttacga agtctcacta
    16321 atcgctgaaa gttaaatcac tattttcagc cctagtggtt atataaatta taattatcta
    16381 accaaaacct taaaaatagc ttttttgata ttttcttttt ctaaaacttt tattcctgtc
    16441 atatgagcat cttctggata acaaactaaa aaatcgcctt ttctaagttc tacatatcca
    16501 ttatttttac catcaagagg taaaaaatct ccctcttctt catatatttt ttgttctaaa
    16561 ttttctataa aatttatatc tattcgttca catccatcaa gcatcaaatg aacatctata
    16621 tacttcttat gagcttccca gaatctatct tctttttcac aagttttata ctctacaata
    16681 ttcacaaaaa tatcatcacc atctattgta taagtacctt tttcataatc tattaatgaa
    16741 ttatctttag catattcaaa acatctaagt aaatcttcat gcaatgttga atatgtctta
    16801 ctatgattta tatttccaaa tatcataagc actatctccc tatataatta taaagtctat
    16861 ttttatactt ttatatataa agtatattat acaatcttat agagtaacta aattatttat
    16921 ctaatcactc tataagacaa tttatcattt aaatattatt tttcataata aacagtagtc
    16981 tcagctcttg gtaaagatac ttttgcttta actttagctt ctattgcact aaatattgta
    17041 cctaccacta cagaagtagt tattgttatt aaagaatatg cccaagaagt tacttctggc
    17101 atacagtatt ttaaataaac aaccaaaatt gctgatacta taaacccaac atatgctccc
    17161 atcttagttg cttttttaca aaatgcacca agtacaaata ttcctgctaa gacacctagt
    17221 actagaccca taaaactatt gaaccattca tatgctgact ttatttctcc atttgctaat
    17281 actattgcaa caactataga aagtatacct acacctaatg atatatattg tgctatctta
    17341 gtttgttttt ccatacttat atcttttgtt atgatagttt gtatatctaa agtccaactt
    17401 gtagcaactg agttaagccc tgttgataaa gttgattgag aagctgcata tattgctgca
    17461 agtagtattc ctgttatacc tactggtaac tcataagcta tatatgatgc aaatacttgg
    17521 tcttgttgaa ctgtttgagc taaatctgga ttttgagtat agtatataaa taaacaagtt
    17581 ccaattaaat aaaatactgt tgcaagtccc attgataaaa caccatttcc atatgtcatt
    17641 ttattaagtt gctttatatc agttgttgta gtaaaccttt gaactatatc ttgactcgat
    17701 acatatgatg aaaaagtatt aagtccagct ccaacaaata ttataaatgc acttgtagat
    17761 agtatatttt tatcaaacat aacttcatta cttgctaaga acttgtgtcc agttgtaaga
    17821 gtatccatta ctgttccaaa accaccattt atacttgcta ttaaatagaa taatgttcct
    17881 gtaacaccta ctattagtac cattccttgt ataaaatcgg tccataaaac agcttttaat
    17941 ccacctgtat atgagtaaat tattgctatt acacccataa ctattatcag tacatttaca
    18001 ggtattcctg taagaccagc cagaactatt gatggaagat acattataat agacatacgt
    18061 cctatttgat atattataaa cattaaagct ccaagcactc taagaccttt gctttcgtac
    18121 ctcatttcta agtactcata agctgtatca atttctaacc tactatatag aggtaagaaa
    18181 aattttattg ttaaaggtat agctataaac atacctaatt gtgcaaacca caaaatccaa
    18241 gtcccaccat aagaatttcc tgctaatgat aaaaacgata ttggacttaa taatgtggca
    18301 aatattgata ctgatgtaac ccaccacgga atagttccat cacctttgaa gaactctttt
    18361 cccttcattt ccttttttga aaataacaat cctgcaaata aaactgccaa taagtaaacc
    18421 actagtattg taaaatctat ccaagtaaat cctaccattt gactaatcct cccatactaa
    18481 aagtatttta ttaaaaatac tttctgtata tttcttttgc tcttgatttc atttcatcag
    18541 ttgcttcttt cataggttgt ctacagtatc cagcctcaac accttgttct tcaagtagca
    18601 atttaattgt ttgatataat ccatttccta atatatctgt tattaaatca ttagtcacat
    18661 gttgtacttc aagtgcttct gatatttttt cattcttagt taattcaaat atttgtctag
    18721 ctctgacacc gtttacatta aatgtagaac caattgcccc atctacacct aaaactgtag
    18781 ctggtaacat catttcatca aatcctgcaa atattaattt atttgggaat gtttttctca
    18841 ttctctctaa taagtagaaa tctgctgctg taaacttaac acctattatt ttttcatttt
    18901 caaataattc tccaaactgg tctaaactca tatcaactcc agttaaaaat ggtatagagt
    18961 atattattaa tctattatct acagaattta ttattgtatt ataatagtgt tttatttctt
    19021 caaaatcaaa cttatagtaa aaaggtgtaa cagcacttat tgcatcatat cctaaatcag
    19081 ttgtaaattt agcaagctct acagcttctt ttaaattgac tgaaccaact tgagctatta
    19141 attttatttc ttccttcact tcatctttag ctatttcaaa tattcttttc ttttcatcag
    19201 ttgaaagcat aaagttttcc cctgtacttc ctcctacata aagaccatct actttacaaa
    19261 catctatatt atgtctaatt atttgtctta accctttttc atttatattt ccttccttat
    19321 caaatgaaac taataatgct gaataaattc ccttcatatc tgttgttctc atatctttac
    19381 ctccaatttt aattttcaag tatagttaaa tataatagtt ttttaattta taaattaatt
    19441 tttaattaat ttcaattgct ttaacaaatt tttctgttat taattgtggt cttgttattg
    19501 ctgaacctac aactgatgaa tagactccta gttcaaaaac cctttttaaa tcttgaggag
    19561 tatttacctt tccttctgct attacaggta tttctaaatc tttaactagt ctttccatta
    19621 atacaaaatc tggaccttct aacgttttag tatatggagt atatccagat agtgtagttg
    19681 aaatacaatc tacaccatat tcttgtgctt tgatagcctc atcataattt gaaatatctg
    19741 ccattaccag aacaccattt tcttttatat actttataag ttcttttaag tcttcattat
    19801 ttggtctaac tctattagta gcatctaaag ctatcatttc acaccctgtt gtcaaaagtt
    19861 catcaacttc ttttttagtt ggtgttatat atatatctga atcttcataa tttctcttta
    19921 taatacctat aacaggaagt ccagtaactt tttttatctc aataatatct tcaactcctt
    19981 gagccctaat tccaacagct ccaccttcca tagcagcctt agccattctc cccattataa
    20041 aaggactatg aagaggttca ttttctaaag cttggcatga tactattaat cttcccttta
    20101 ccttatctag cattttttca attacctcat ttctgaaatt tattttcttg atttatgtat
    20161 taataataac atgaaaactt tttctttgca atattttttc atattttttt cttaactcta
    20221 tatttttact gatttattct atatattagt ctgtttttta tacttaaaag aaattttatt
    20281 tcattttttt ggtgtttatt ttcattttgt ataaccacta ttatatgtat tctatataaa
    20341 taatttcaat aaaaaaaccc atgtatacta tacataggtt tcccaatatt attctaaatc
    20401 cattataatt tttcttccac aacatggaca aaattcagcc tctgtatcta tctcactttc
    20461 acaataacca caaactataa aatcatcaca ttcattttcc aattcaaatt ttttgccaca
    20521 ttcagcacaa tatttatcat ttacatttcc aacatagcca cattcacaag ttacattact
    20581 ttctaccatt tccatttcat taatttccat atttttttca taaattaact tatcaagttc
    20641 tagtaactca tcacagaatt tatcaaaact attatcatca atagaatctt ctctaatttt
    20701 ttgatatgtc aatattccca tttccaagaa tatctttgct ttcttttctt ggatatcatc
    20761 aatctctcta tttaactttg atttttcttt atataattca actttaaatt ttccattacc
    20821 aaacttcttc ttaaccttag aaaatttatc atctacttta ttattaatat ttccttccac
    20881 agatgttccc tccaatcata tttaatcagc tgagtttagc ttataaccta ttaaagatat
    20941 cacaaaacta tatataaatg aaattacaat agcttgtaag actttaaatt gcattattaa
    21001 agttgctcca taactagttg tattaaagaa attaatatta ctatctagta taaatgtact
    21061 aaataaagcc aacatcccca ttaaaaaagc ataatatata ctaaatacta ctataggttt
    21121 tatactatcc gtattatact taaatcttag cttgtatcca tttaataata atattaacat
    21181 agataatgct cccattgcat aaaacattaa tttagtatct ccaaataaag atgaagaact
    21241 caaagtaaac attgatactg ttgaatttat tatggttact gaaattccat ttgcaaaagc
    21301 ccacatatag ctagctattt gtggcagtat agtaaataaa tttaatccat ttgagtaact
    21361 actcatatct agttcattta agtaactact atcagatata gttagtacaa atagtattat
    21421 taatactaaa acataaccta atataaatgt ttttatagaa tttgaaaaga gagataaata
    21481 catattttcc ttttcataac tttttttata agtagttatg tatgtacata taaaccctaa
    21541 tacaaatcca tttaaaagga cactaaaaaa ttcataacta tattctaatg catatccata
    21601 ttctaacata ctatgtgaac tagtttttac attagtaaaa atagataaaa tagctaaaac
    21661 taatccataa aaaattccaa cacctataga atttgctaat acagattttg aatctctaca
    21721 tctttttctc ataaaaatta agtttgatat taataatacc aaaataggaa ttataagtaa
    21781 tattaacaaa cctatattgg catttataaa cccagaaccc atcatggtag acatagatac
    21841 actaatttga cctaagttga gagctaggat tatatgtgct ggatttatta aataactaat
    21901 atcattaaat tgaatagtta taatagcttt aaatatcaat gcaataataa ataatataaa
    21961 tatggttgta aatgttgtta aaaatactcc tcttttattt gcatgatatg aaagctcttt
    22021 tattttagat tttaagtcta gttttgtttc aagtggtctt aatgatgtta tttcataaag
    22081 ttcatttcca caaaatttac agtaattatc cttagtatta ttttctttat tgcaactaga
    22141 acaaattttt tcttctttat ttttaagagt gatatggcta ttttttattt ttctagttgg
    22201 ttcacctgtc gttttggaat aattattatg tgaataattc atgttattta ttttcttttc
    22261 acccattttt cccctccaag ttttactatt gtaaattatt aaatacaact atatcatata
    22321 aaacttaatt ataccttaat tggatatatt tatctatttt atttgtttat tgctgttgtt
    22381 ttttaacagg tcttgatatt taaatatctt gttaatgcta actttattat ttacatttta
    22441 ttatgcttaa tttaaattta ttttattctt tattttcagt agcaaactat ctttaaatct
    22501 taattataat aaagtattaa ccaataaagt tattcaacat tagctaataa attttatcca
    22561 ttacaatttt agattgttac acacaatata ttttgatata atcaaattat aaacaaagta
    22621 ttccaagtat ctaaagacat aaaggaatac ttatttttat gctttatttt taatggaggc
    22681 ttatatgaac ttagaaaaaa ttaaaaaatt ttggggattt cctctagata aaaaacataa
    22741 agaaaatgtt gaaaaagaac tttgcaatta tctttaccat actggtaaaa tcatttgcat
    22801 aataatagta atatctcaaa taattatgat gatatcaatc tccgctagag agggaggtcc
    22861 ttttgccaca ccaagacgcc aatggtattt ttatatgtat gtaacactat tttgtgtatc
    22921 ttctgtcttt atgtttgtat tttcttatct ttggaataaa aaaaaggatt gttgtacttt
    22981 ttatataaat ttatggataa tttatgtaac ttttttctgc ctatggggtt gtgtaattac
    23041 tctacttgac cagttaggtg gaaatgacct aagtgtattt agttacatta tgctagcagc
    23101 tgcagctttc tcagtattaa aattaggaga atcagtaata gtttttggag gatgtttttt
    23161 gtttcttaat tttttcttac ctggtattca aactatacca ggcaatgagt ttagtaatat
    23221 cgtcaacaca ttttttataa catcccttgc cgtttttgtt tctacaatgc tatatagaag
    23281 tcgtgtattt acttactatg acaaactttt aattagtcaa caatatgaag aaatatatca
    23341 tataaataat ttacttaacg acaaagtcat gacagatgac cttactaaaa tgaataatcg
    23401 tagatacctt gaagatattc tacaaaaaaa attaatcagc catgcaaatc aagaacctat
    23461 aactggaatg atgatagata tagattattt caaacaattt aatgacaatt atggacatca
    23521 aaagggagac tattgtttac aaaatattgc caaagtaatt ttggatttta caagttctga
    23581 aaatgaacat gctatacgat atggtggtga ggaatttttt atatgtattt ttaactgtga
    23641 tgaggaagat gctaaactta aatcagaatg tttacgaaaa attatagaga cctgtaattt
    23701 tgagcgtgac gatatccctt taaaatgtgt aactgttagt atcggagtct acacaaataa
    23761 aattgaaagg acaataacgc taaatgagtt tataagtaat tgtgataagg ctctatatac
    23821 tgcaaaagaa cagggacgta attgtgttgc attttattaa aaagttacat actattacat
    23881 aaacctataa gtattatatt gcaaaataaa agtaaccaaa ttatatattt atagtacaat
    23941 aaaaataact tgcatatctc taaaatagat aaatatgcaa gtcattttag tgtttacact
    24001 taaaattata taagttttat tatatataat tattaaaatt cagcattttt aggagttctt
    24061 gggaaaggta taacgtctct tatgttagac atacctgtca tatacataat tattctttca
    24121 aatccaagac caaatccaga gtgggtagca gtaccaaatt ttctaagttc taaataccac
    24181 caataatctt cttctcttaa tcccatttca ttgattctat ctagtaatac atcttctctt
    24241 tcttctcttt gagaacctcc tacgatttct ccaactccag gaactaataa gtccattgct
    24301 ctaacagttt taccatcttc attcattctc atatagaaag cttttatatc ttttggataa
    24361 tctgtaacaa acactggaca attatatatt tgctccgtta tatatctttc atgttcagtt
    24421 tgaaggtcac atccccactc aacaggatac tcaaagtcat gaccagattc aattaataat
    24481 tccactgctt tagtgtatgt tattctaaca aactcagagt ttactatctt atttaatctt
    24541 tctaacaatc ctttatctat aaaactatta aaaaattcca tttcttcagg agcattttct
    24601 aaaacatagc ttataacata ttttatcata tcttctgcaa gttccatgtt atcttcaagg
    24661 tctgcaaaaa ctatttctgg ctctatcatc caaaattctg aagcatgtct tcctgtataa
    24721 gagttttcag ctctaaatgt aggtccaaaa gtataaacat ttctaaaaga aagtgccatt
    24781 atttcggcat ttaattgacc actaactgtt aaattagcct cttttccaaa gaaatcttga
    24841 gtatagtcta ttttgccatc ttctgttttt ggaatatcat ttaaatccat agttgttatt
    24901 ctaaacattt ctcctgcacc ttcacagtca ctacctgtta tgattggaga atgtgcatat
    24961 acaaagtttc tctcttggaa aaatttgtgt attgcatatg cagctattga tcttactcta
    25021 aatacagctg aaaaagtatt acttcttggt cttaaatgtg ctatcgttct taaatattca
    25081 agtgtatgtc tcttcttttg tagcggatat gaactatctg attcgccttc tacaactatg
    25141 ctttttgcat gtatttctac tggctgttta gctccttctg tagatactaa ttctccctct
    25201 acaagtatag atgagcttat tgctaatttt cctacctctt taaaattttc tactttctca
    25261 tcaaatacta tctgcatatt tttaaagaag cttccatcat ttagctctat aaatccaaaa
    25321 tttttagata ctctagacgt tcttatccat ccagctactt ttacagtctt ccctatgtac
    25381 tgttcttttt ctctatacaa ttcttttact gttataaatt ccttttgcat tttaaatcct
    25441 cctagtataa ttgttattaa tttcttttaa atatagtttc aataaaaaaa gcccttcatc
    25501 cctatataaa gggacgaaag actattactc tcgcggtacc accctagttg tcataatgac
    25561 ctcttagtta agcaatgctt aaagcctata acggtgcctt ccgtctaagt ctacttacta
    25621 aataagcttt cgattagaaa ctccaagatg ttcttcaata taaacctcgt attgagcttt
    25681 caccatcctc aactcgctag aactacattt tatatctact cttctcttca tagtatttat
    25741 cttttattat ttctgctaat taacaaaatt ataccaattt ataaattttt agtcaataaa
    25801 tttatataat tgatactgat tgctatttaa aatataataa ctctaccttg caaaatgaca
    25861 ataaacactt atctttacta cttcagtttc aaaactttta taatttactt ccattatcaa
    25921 cccagtcttt tgcttctgta acacccttaa ttgaaggtat tgaaacttta ctatgaggtt
    25981 ttaatttttc aacatcagcc catgctgctg tcgactcatt tccaactaaa agtgaacttt
    26041 taagtctttt attatcttta ccttttaatg ctcttgcttt tttattttcc aaaactatca
    26101 cctctattat ttattttgta atagttttag caatttttca aataaaattc ataagttaaa
    26161 attataatga tttttaagtc aataacatat cttttttata ctaaatctat aattatttt
//
LOCUS       DBGJFK010000052        26051 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.052, whole genome shotgun sequence.
ACCESSION   DBGJFK010000052 DBGJFK010000000
VERSION     DBGJFK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26051
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.052"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            40..891
                     /locus_tag="ACOIAP_002490"
     CDS             40..891
                     /locus_tag="ACOIAP_002490"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HGZ2639372.1"
                     /translation="MKNIISAKELISKLEQNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNNTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEKKVNVPSCTGKEIKPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1019..2632)
                     /gene="ggt"
                     /locus_tag="ACOIAP_002491"
     CDS             complement(1019..2632)
                     /gene="ggt"
                     /locus_tag="ACOIAP_002491"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HGZ2639373.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLIECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSRKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELKLEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPEHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVESEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2864..4801)
                     /locus_tag="ACOIAP_002492"
     CDS             complement(2864..4801)
                     /locus_tag="ACOIAP_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639374.1"
                     /translation="MTLFRIAMKNVKNSFFNYLMYFISIVFSVFIFFSFKSIEYNKAL
                     SSLGEKTRMSINTSSILIVAFVFLFIYYSNSFFFNRRSREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLT
                     IFIVIGIRNTIVIRNKRIIELFNKPPEKCRFKKFIKLKGALGVLLITISYLMSISYFI
                     AENIMFSVFILVTIIPGTFLFFSSVMYMIIDAVKKRKGFYYKGQNLIAFSELGFKLKS
                     NSSVLAIIAILIATSVTILGFTISLYYDIDRNISENYKYSYTINLGNSHVNNKIDKLL
                     DKYKKDNKIIFDKTIELIDKDINLEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELISKESVYYVSDSYKKILFKDFEIEKINLHFKDTSECDINLFTVQKTILEPEIN
                     SQATFDLIVVKDKVFNQLKLHGDSRLIRLIDIKNEKKELNLTLKLKNIVSENMEFTYP
                     FNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDRERYIMLT
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIVQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMITE"
     gene            complement(4788..5555)
                     /locus_tag="ACOIAP_002493"
     CDS             complement(4788..5555)
                     /locus_tag="ACOIAP_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639375.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRINEISRELNIESILDKYPSEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5778..6452
                     /locus_tag="ACOIAP_002494"
     CDS             5778..6452
                     /locus_tag="ACOIAP_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639376.1"
                     /translation="MFKIMVVEDDVSLKNIIAECLTKWGHNVHQIENLENIIEEFKNY
                     KPQLVLLDINLPFYDGFYWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSIDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIN"
     gene            6476..7480
                     /locus_tag="ACOIAP_002495"
     CDS             6476..7480
                     /locus_tag="ACOIAP_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639377.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTIAVIIFSPVDVFLIDTILYI
                     LVINVVFLFLYLFISYIKKNKFLDKIKNDTFKININTTELAKCKNEEKIYLNIIKNHQ
                     YQCNNIINKNIKKFEENKEILNMWVHDVKIPIAIIKLTLEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILNLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRSKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIAVDSEYNQYTKFTITFKCDL
                     "
     gene            7591..8823
                     /locus_tag="ACOIAP_002496"
     CDS             7591..8823
                     /locus_tag="ACOIAP_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGZ2639378.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRSSSFGSSGFNSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTKLQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENRDAIASINAQITTLNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVSNSSFKIPASCVLKDKKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     NGDTTPNKKVEEVNMDVN"
     gene            8831..9505
                     /locus_tag="ACOIAP_002497"
     CDS             8831..9505
                     /locus_tag="ACOIAP_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639379.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKSLKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9508..10740
                     /locus_tag="ACOIAP_002498"
     CDS             9508..10740
                     /locus_tag="ACOIAP_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639380.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLIPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVISKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIIATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11025..12290)
                     /locus_tag="ACOIAP_002499"
     CDS             complement(11025..12290)
                     /locus_tag="ACOIAP_002499"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGZ2639381.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMVKAKELDVPLSFHEEDPSLVGNPGVNAGKIASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSREEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSTNPAKLYNLNTGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKINYTICNGKIVYNA"
     gene            complement(12343..13491)
                     /locus_tag="ACOIAP_002500"
     CDS             complement(12343..13491)
                     /locus_tag="ACOIAP_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HGZ2639382.1"
                     /translation="MKSVSVRSCKTYNYEEVRLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKVHSEKAHVLKYMDIIKPVVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLIPNRVATIRGAIKRGYIREDFSDIEILG
                     EDINDLIIKNYKVPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPAATIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13582..14127)
                     /locus_tag="ACOIAP_002501"
     CDS             complement(13582..14127)
                     /locus_tag="ACOIAP_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HGZ2639383.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(14350..15294)
                     /locus_tag="ACOIAP_002502"
     CDS             complement(14350..15294)
                     /locus_tag="ACOIAP_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGZ2639384.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVIVQAFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            15680..16561
                     /locus_tag="ACOIAP_002503"
     CDS             15680..16561
                     /locus_tag="ACOIAP_002503"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2639385.1"
                     /translation="MVKKRKKKTVALTIIVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAIKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPGRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(16622..17830)
                     /gene="tyrS"
                     /locus_tag="ACOIAP_002504"
     CDS             complement(16622..17830)
                     /gene="tyrS"
                     /locus_tag="ACOIAP_002504"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGZ2639386.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKDGSVNPRDIKMNLAREIVTLYHGEESAREAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVVNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(17903..18155)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18306..19274)
                     /locus_tag="ACOIAP_002505"
     CDS             complement(18306..19274)
                     /locus_tag="ACOIAP_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HGZ2639387.1"
                     /translation="MNTTKKLTEAALLSSLFIVVTIISVSTGFGYAIYLDFIVPIFFC
                     IICLKCDLKYTILSGITSLLIISLVLGNLGTAIWATQSVLLGIMCGYLINKPTMVMDD
                     LVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLMIALFPFG
                     MVFCIYLLSLILGNKLHILDSNSLKKLLIFKNFRTLNQFLCCSKKVFYICVSYLTIFE
                     VVKLLNVKVDFVYLKTVFISIAYLCVYFIIRDSCMSLQNFIIAKFRKLLYARISFLII
                     ILLLFFMFDVTVISLIIINAFLNKKINIRLSQNNIVNKQINLLIEK"
     gene            19447..19887
                     /locus_tag="ACOIAP_002506"
     CDS             19447..19887
                     /locus_tag="ACOIAP_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639388.1"
                     /translation="MFKIKHFNDLNLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKN
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSRHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            20214..20441
                     /locus_tag="ACOIAP_002507"
     CDS             20214..20441
                     /locus_tag="ACOIAP_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGZ2639389.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            20467..22587
                     /gene="feoB"
                     /locus_tag="ACOIAP_002508"
     CDS             20467..22587
                     /gene="feoB"
                     /locus_tag="ACOIAP_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HGZ2639390.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKHKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEAIKKGITIDKKLLEDSLC
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(22700..23518)
                     /locus_tag="ACOIAP_002509"
     CDS             complement(22700..23518)
                     /locus_tag="ACOIAP_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2639391.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKSEEYLVLSSDLSNMSNGDFMMELIDFTNYCK
                     AKNLYQGYELGVIVSNENLKNGDYLSISSFYLKIDKKIKDKRLYIKPEGMYACIKHIG
                     KYENSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            complement(23972..>26051)
                     /locus_tag="ACOIAP_002510"
     CDS             complement(23972..>26051)
                     /locus_tag="ACOIAP_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2639392.1"
                     /translation="FEVILNQLQINIYVTNIHTNEIVFMNKKMKEEYNILDPEGKVCW
                     QVLYPEKNSTCSFCKVVELLKNDKKGVLIKWYEKCNKLNCVFENYDSLITWQDGTVVH
                     MHQSIDITNSTSLNKQIKPNEFHKISNTEEEKGVFNVSIDNFDYNSTLLYDALIRGTD
                     EYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLIYWEKIVHPEDWKRFYKSNTEIGK
                     NQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGKPSIFAGIMTQLGKQNKIDSLTQL
                     LNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQSIQSI
                     LPDNAELYKLDGDEMGIIVDNVEEKEILTLYNQIQNMIIHLQLWRKYGLNITISAGCV
                     IYPKHGDTVKELYKYASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLKASIND
                     DFRGFSLRFQPQVDTQSHKIIGVEVLLRWTNDKYKAISPLEFIPILEEHDMINTVGAW
                     VLRMALRTFKGLIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDEKFPYQNLVLELT
                     ESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDVVKIDRVFVKDI
                     LKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQMKPDYIQGYLFGKPQTAT
                     EIFDLLKLDN"
BASE COUNT         9100 a         4038 c         3219 g         9694 t
ORIGIN      
        1 attaaaataa aaataatata aacataggag gtacattttt tgaaaaacat tatttctgca
       61 aaagaactta tatcaaaact agagcaaaat gataatctag ttgtaataga ttgtagattt
      121 gaccttatta atagaactta tggtattgat tcttataaaa aaggccatat aaaaggtagt
      181 ttcatcttag atatagacaa ggatttatca tctcctacaa aagaacatgg tggtaaaaat
      241 cctttacaag accctttaat actaaaagaa aaattagaaa aaatgggtgt tgataacaac
      301 actacgattg taacttatga tgatggagat ttaaatggag cttgcagatt atttttccaa
      361 ttaaaacatt tgggtcttaa aaatgtctat gtactagacg gaggaataac atctttcgta
      421 aaagaaggtg gagaattgga aaagaaagta aatgtaccaa gttgtacagg taaggaaatt
      481 aaaccaaata taaataatga tttagttgtc ccaatggagt atgttaaatc taaattatac
      541 aaaaaagata ctgtaataat agattgccgt gctaatgaaa gataccaagg tttagttgaa
      601 cctgcttact caaaagctgg tcatatacca agtgcaaaaa attatttttg taaggattta
      661 ataaaaagtg actttgaaaa tggctcactt aaagatatag aatttttaaa aaaattcttt
      721 aaagatttaa ataattatga tgaagtaatt ttatcttgtg gttcagggat atctgcttgt
      781 gttaacagtc ttgcccttag agaacttgat atacctcata agatttatat tggtagcttt
      841 agtgactgga ttagttatga tgacaatgaa atcaaaactg gccaagaata aggctaacaa
      901 tatataaaat cataggatag cttaaatttt gtaaaggcgt cagtcattgt agactttcgc
      961 ctttaattat tatttcatat actctttaaa tttattatat atattttagt tgataatatt
     1021 aatagactgc aatatgacca tcacatcttg actctgtccc acagatataa ctttcctgtt
     1081 ctgttttaaa tattatttga cctcgtccca tgtcgacagt atcatgaatc acttttattt
     1141 catgaccctt ttcaattaat gaatctatta tatgctttgg catctctgat tcaacttcta
     1201 tttcctttcc ttttatccac tgccatcttg gagcatctaa cgcttcttgt ggatttaatc
     1261 caaaatctat catatttgtt aatacttgaa tatgaccttg tggttgcata aaagctccca
     1321 ttacaccaaa tggtcctatt gctttatctt ctttacctaa aaatccaggt attatagtat
     1381 gataaggttt tttaaatggt tttactacat tatggtgttc agggtctaaa ttaaaattat
     1441 tacctctact atgtaaagca atcccagttc ttggtatcac aattcctgaa ccaaaattta
     1501 tgtaattact ctgtatatat gaaaccatat ttccatcctt atctgcagtg caaaggtata
     1561 ctgtaccacc acaatatggc tctcctgcag ttggatacag agcctcttta ttatcaatta
     1621 atagacttct ttttttggca tactcttggc ttagtaattc ctgaatcttt accttcatgt
     1681 gctctatatc agttacatat gttttagaat ctgcaaaagc tagctttaaa ctttctataa
     1741 tcttatgtat gtcttctaca ttttctatat ttccttctag tttcagttct tttaatatat
     1801 taagtgccat taaaactgtt attccatgcc catttggtgg gatttcaaat attttatatc
     1861 ccttatattc tgtacttatc ggttctaccc atgttggata aaaacactct aagtcactct
     1921 ttcttatagc cccattaaat tttctagaat attcatctat tttatcagca agtcttcctc
     1981 tataaaaact ttcagcttga gtatttgcta tctcttctaa tgtacttgcc tgttcttcac
     2041 atataaatat atctccagcc tctggagctt taccatcttt agaaaatgta tcaaaccatg
     2101 gcttgaactc ttctccaata agttctttct catatagttc atatgatttt ttccatactt
     2161 tagctacatt aggagatact acatagccct ctcttgcata gtttatcgct ggagataaac
     2221 attctattaa gctaagctta ccatattttt tatttaattc tgaccaagct gcgggtatac
     2281 caggcacagt tactgctcca aacccatact ttggcatttc cttcatatta ttataatttt
     2341 ttaattccat attttctgga gcaaagccac tagaatttaa accatacaat cgtttttctt
     2401 cctctatcca aacaagggca tatgcatctc ctccaatccc attacttgta ggctctacta
     2461 ctgctaatgt agcagctgtt gcaactgctg catcaacagc atttccaccc ttttttagta
     2521 tttcaagtcc agcttgagat gctaatggtg ttgatgttgc aactgctcca tttttagcat
     2581 acacgacatt tcttattgat gagtatttat gttggtaggc attaaacttc ataaatttca
     2641 gctcctcgtc attttttatt tgatattctg cttaaattta ttatataaca tcaagtaata
     2701 taactgatac aaaatgatat aaaatataga ctttttccta accctaattt tatcattaaa
     2761 taaatatctt aagctcaatt ctagtatttt ctatttgcac ttaaataaac tattttattc
     2821 aaaacataca tctaattatt ttaacttaaa aataatttat tatttattct gttatcatgt
     2881 ttagagcata ttttaaagtt aaaaaataat atataaaata tcctataaaa taaatgacta
     2941 gagttatgat aattggtaca agtaatgacc ttggtataaa cttttgtact atagacatag
     3001 caaataaatt atgaactgta cctacaacta atggcattaa aaatatgact tttaactgtt
     3061 ttgatattat tttctcaata tctttattat ttgctccaag ttttgttaac ataatatatc
     3121 tttccctatc atcatatata tttgataatt gtttaaacaa aattatacta cctgtgcata
     3181 aaagaaatac tacagataaa aatataccta taaacagcat tagaccactt aattttatca
     3241 gattgtcata actttcaata ctggatgtaa aattaaaagg ataagtaaat tccatatttt
     3301 cacttactat attttttaat tttaaagtca aatttagttc ttttttttca ttttttatat
     3361 caattaatct tattaaccta gaatctccat gtaattttaa ttgattaaat actttatctt
     3421 ttactacaat taaatcaaac gtagcttgtg aatttatttc tggctctaag atagtttttt
     3481 gtactgtaaa cagatttata tcacactcac ttgtatcttt aaaatgtaag tttatttttt
     3541 caatctcaaa gtctttaaaa agtatttttt tatatgaatc agaaacataa tacacagatt
     3601 cctttgaaat taattcttca taattgttat tctgatattg tcttaatttt ttaaaatcac
     3661 tttctctgat aatatctaca gaagttctat cttctatata actatttcca tttttatagt
     3721 acatttcaag atttatatct ttgtctataa gttctattgt tttatcaaag attatcttat
     3781 tgtctttttt atatttatct aataatttgt caattttgtt atttacatga gaatttccta
     3841 aatttatagt ataactgtat ttataatttt cacttatatt cctatctatg tcgtaataaa
     3901 gcgatatggt aaatcctaat atagttacac ttgtagctat taatattgct attatagcca
     3961 acacactact attgctcttc aatttaaatc caagttcaga aaatgcaatt aaattctgtc
     4021 ctttataata aaaacctttt ctcttcttaa cagcatcaat aatcatatac atcactgacg
     4081 aaaaaaataa aaaagttcca ggtattattg taactaatat aaaaactgaa aacataatat
     4141 tttcagcaat aaaataacta attgacatta gataagaaat agttattaat aaaacaccaa
     4201 gtgccccttt taactttata aattttttaa acctacactt ttctggtggt ttattaaata
     4261 actctataat cctcttattc ctgataacta tagtatttct tattccaata actataaata
     4321 ttgttaaaaa cacagctagt gtctgaacta aagcctttat acttaagttc atatttacta
     4381 ctatcatttc attcattaat tttacaagca tcatagtcat aagctttgaa aataacaatc
     4441 ctaaaaatat acctattagt attgcaacta tccccatcaa aaaagtttca tataaaaata
     4501 tttttcctat ctgatttttt ctcattccaa gtaaactata agtacctact tctcgactac
     4561 gtctattaaa aaaaaatgag tttgaataat atataaataa aaatacaaat gccactatta
     4621 aaatcgaact ggtattaatg ctcatcctag ttttctctcc aagtgaactc aatgctttgt
     4681 tatactctat agatttaaaa ctaaaaaata taaacacact aaatacaatt gaaataaagt
     4741 acattaaata attaaaaaaa ctattcttca catttttcat tgcaattcta aataaagtca
     4801 tttttgttaa ctcctccaat taaggaaact gtatttacta ttttattata gaactctctg
     4861 ttactttctc cttttacaat ttctgtaaat attattccat cttttataaa tagtatccta
     4921 ttgcaaaaac tcgcacttat agcatcatga gttaccatca atattgtttt attactatct
     4981 ttgtttaatt tcaatagaca gttcaacaaa tctctagcag atttagaatc taatgctcct
     5041 gtcggttcat ctgcaagtac taatgatggt tttgttgcta tagctctaca tacagctcct
     5101 ctttgctttt gtccaccaga aacttcacta gggtatttat ctaatataga ttctatattt
     5161 aattctcttg aaatctcatt tattctattt tctattactg atactctttc attttttaaa
     5221 gaaagaggca acattatatt ttcttttatt gtaagtgtat ccaaaagatt agaatcttga
     5281 aatacaaatc ctagattatc acgtctaaaa tccgccaatt cattttgctt cattttaata
     5341 gtattctttc catttatata aatatctcct gatgaaggta agtctattgt agaaataata
     5401 tttaaaagtg ttgatttacc agcgccagat gaccccataa taccaacaaa ttctccttta
     5461 taaaccttga aagttattcc tcttagagct tcatgttttg aaccttttct tccatactcc
     5521 ttttttatat tttcaacaga taatatttct tccataattc ataatcacct ttcatcataa
     5581 ttagttattt gtcaattctc acaaatatat tatatatatt aaaatagctt ttaaacattt
     5641 aattatatta atttaaggtt acattttcgt aagtattaat tatatttctt caaatttatt
     5701 gtaattatgt ttaaaatata atttatcaag taaaatatag ttatgttaat ataactattt
     5761 taaattggga ggtaagaatg tttaaaataa tggtagttga agatgatgtc tcattgaaaa
     5821 atatcatagc agaatgtctt actaaatggg gacataatgt tcatcaaata gaaaatcttg
     5881 aaaatataat agaagagttc aaaaactata aaccacagtt agttttattg gacataaacc
     5941 ttccatttta tgatggtttt tattggtgta atgaaataag aaaaatttca aaagttccta
     6001 taatctttat ttcttcaaga aattctaata tggatgtaat aatgggtgta aatctaggtg
     6061 cagatgatta tatacaaaaa cctttttcta tagatgtctt agtggctaaa gttaatgccc
     6121 ttttaagaag aacttataat tttgttgata ataactcaaa tcagattatt cacaatggtg
     6181 ttactttaga tttatcaact gcaacaataa actatgaaga taataccatt gagctaacaa
     6241 aaaatgaaat caaaattctc catgagctta tgaaatataa aggtcagata gtaagtagaa
     6301 ataaactcat gaaaaagtta tgggataatg attggtttgt agatgataat acattaactg
     6361 tcaacgtaaa tagaatacgc tcaaaattaa atgaaattgg tctagaagat tttatagaaa
     6421 caaaaagagg attgggttat ataatcaatt aaaacgattc taagtaggtg aatttatgag
     6481 ctttaaagat tttctcaaag ataagttagg ttttttagta tacaatttta ctttcttaat
     6541 ttttacaata gcagttatta tattttctcc tgtagatgtt tttctgattg atactatttt
     6601 atatatatta gttataaacg ttgtgttttt atttctctat ctatttatta gctacatcaa
     6661 gaagaataaa tttttagata agataaaaaa tgatacattc aaaattaata taaatactac
     6721 agaattagct aaatgtaaaa atgaagaaaa aatatatttg aatattatta aaaatcatca
     6781 atatcaatgt aataacataa taaacaagaa tattaagaag tttgaagaaa acaaagagat
     6841 tttaaatatg tgggtacatg atgtaaaaat tcctatagct ataataaaac tcaccctcga
     6901 acaaaatgaa aatttaattg atgaaaaaat ttcagatgac atagatagtg aaatatttag
     6961 aattgaaaac tcagttgaaa aaattttata tttatcgaga cttgaagatt ttcataagga
     7021 ttttttaatt caagaggtaa atattgaaaa aataattaga aatattataa aaaaatactc
     7081 aaaatatttt atttcaaaaa aaattatttt aaacttaaat aatttgaatt ttaaagtttt
     7141 atctgacgaa aaatggctct acttcatatt cgagcaatta ttgagtaatt ccctaaaata
     7201 ctcctcatta ggagataata tatctatcta ttgcaaaaga agcaaaaatt atttacaatt
     7261 aagggtggaa gatactggct gtggtataaa aaaggaagat ttaaatcgaa tattcaataa
     7321 gggatttaca ggtaataatg gaagaaacaa ttctaaatct acaggacttg ggctttattt
     7381 agtaaaagaa ctttgtgata agcttggcca taaaattgct gtagattcag agtacaacca
     7441 atatacaaaa tttactatta cattcaaatg tgatttatag tatcttatta ttgatagttt
     7501 attttcatta acttatattc aacttcttat agtaattcta tatgtacatc ccagtatata
     7561 ataagtagtt tttataaaaa ggaggaagac atgtcttttc taaaaaaatt taaaaataaa
     7621 agatttagaa ataacagttt taaaagtaac aactttagaa gtagcagttt tggaagtagt
     7681 ggcttcaatt ctaagaataa gggttttaaa aacaatcctt ttaaaaataa gagattcaaa
     7741 atatatgcag gaatagctgt aatcatactt ctaattctag gagttcttgc ttatgttgat
     7801 tcaaaaaaca ctaaattaca agctaatgaa aactttatcg aaacatatac tattcctgaa
     7861 aatgaaaaaa tatttataaa tgggatggtc gttcctaagc aaactaagga tttcaatata
     7921 tctggagatt atgagttaag tgatgttaat gttacaaatg gtcaaaaagt aaatcaagga
     7981 gaccttcttt ttactgctaa aaatccaact ataatagcag aaatagatag tttaaaatca
     8041 caacttagtc aatacaaaaa acaaaaaata tcactttctg atattgctga aaatagggat
     8101 gctattgcct ctataaatgc acagataact actttaaact ctcagatagc ttctctggat
     8161 aaaaaagcgt atgacagagt tactgcacct tttgatggta cagtatactt gaatgaccaa
     8221 actggaaacc cagaccaacc agtctcattt atgactatcc aaggtctaga gttttatatg
     8281 aaaggacaag caagtgaaca agatttacct aaaatgaaga ttgaccaaat ggtcaatata
     8341 ttagtttttt caactgacca aaagcttact ggtagaataa gttttatatc tgataaacca
     8401 tctactccaa acactgaaat gggagctcag cagaatacac tgtcttatta tgatataaac
     8461 atagcatttg ataatcaaga aggattagta aatggattcc atcttcaagc atcacttgaa
     8521 gtatctaatt caagctttaa aataccagca tcttgtgtgc ttaaggacaa aaaacactca
     8581 tatgtattta aggatttaga tggtatattg aaaaagcaaa ttgtagatgt agcaagtcaa
     8641 aatgatgatt ttgctgtagt tagaggcggt cttgaacaag gcgatataat aataaaacac
     8701 cctactaaag aaatgaaaga aggagaccca gttcaaggtg atggcgtaac tgctggttct
     8761 aataataatg gagatactac tccaaacaaa aaagtagaag aagttaatat ggatgtgaat
     8821 taatttacat atgttaatta aattagaaaa tattcaaaaa tattacaaag tagggaaaga
     8881 tgaattacat gttttaaaat ccttaaattt agaaattgaa tctggagaat ttgtcatgat
     8941 aatgggtaaa tctggtagtg gtaaaactac tttacttaat atcttaggtt ttctagatgt
     9001 atttgatgaa ggaagatata tatttgatgg aacagatgta actaatttga gtgaaaatga
     9061 acgttctgtt tttagaaata ttaatattgg atttgttttc caacaattta atttaataga
     9121 aactctaaat gtatatcaaa atgtagagtt gcctctaatt tacaataaat cgctaaaaaa
     9181 atctaataga gaagaaattg ttaaagataa attaagttct gttggacttt tggataagct
     9241 taaacaaaaa ccgcttcaat tatctggtgg tcaacaacag cgtgtagcca ttgcacgttg
     9301 cttagcaaat gaccctcaaa ttatctttgc agatgaaccg actggggcat tagatagtga
     9361 aactagcaga gaaattatgg agcttttaac aaggctcaac aaacaaggta agactataat
     9421 aatggttaca catgatcaag atttaactaa gtatgcaact aaggttatac gacttaaaga
     9481 tggtgtgttt acttcggagg tgtaatcatg agtttattaa aaaattcttt ggccaattta
     9541 aaaggtcaca agcttcgtgt atttgtagct ttactctgga ttataatagg aataacttca
     9601 gtgatacttg ttagttctat aggtaatgga tttcaaaaag aaattaaaaa atctgtaaac
     9661 aatgtaaacc ctaataaaac tactatttca tttgagtcag ctgataacac aggtcttact
     9721 gatgatatga gtattttttt aaaaccattt aacgcgaaag acttagaaga gttatcattt
     9781 gttgaaggag tagaaagaat agctccttca agagatgggt ttaaccttga ttcagtttac
     9841 tcttcacaag catcttttga taaaaaaact acgtatgttg atgttggacc agtaaaaaaa
     9901 gattctaaaa taaatttaat ttgtggtaga gatttttctt tagatgatga aaaaagaaaa
     9961 gtaattttac ttacattaca aagtacaagt gaaatttttg aaaatccaga agatgcctta
    10021 ggtcatggta tcaacataaa tggaactata tttgagataa taggtgtatt ggatgattct
    10081 cagcaaaacc aagctggagg attctttgga ggttaccaag atatgcaatt tactacttcc
    10141 cttataccta aaaaagcttt tgacacttta atgagtcaaa attcttattc aaatgaaatt
    10201 taccaattag acttagtttc ctctaaaggc tataatgtaa atgaagttgc aaacaatgtt
    10261 atatctaagt tatatgaaat gcaccctggt atcaatggtt cttatactac accagaccca
    10321 actgaacaga cagcttatct tgaaagcatt aattccaatg taaacaaata tgtatctata
    10381 ataactgtag ttgcaatgtt tgttggtggt attggtgtaa tgaatataat gtatgtatct
    10441 gttatggaaa gacaaagaga aattggtata agacgtgcta ttggtgcaaa gcctaggtct
    10501 atattatttc aatttttagt tgaagctgtt tttataacag tatgtggtgg aattttagga
    10561 actatagttg gatttgctgc tacaaactat gtttctaaat atataggctt tgaagcaata
    10621 cctagcttaa atagcttgtt ttatgcaatt atagctacta tattgactgg agttgtcttt
    10681 ggtcttatac cagcctttaa agcctctaaa ctagacccta taaaggcaat ttataagtag
    10741 aaattgtata aagattttcg atttttaaat tagtttatat aaaacatact taaatatata
    10801 acgcactatt atatatgata gattaataat ttaatctttc caaatataat agtgcgttct
    10861 ttcataaaag ggattctctt ccttctatat ctaaattacc aatatgtcat accctaactg
    10921 ttcaagctaa tatttccaat ttggattaat caatctcctt ttcctaatat acaatctttt
    10981 gctctcaaca attgtatcac ccaccttaaa aaaataatct taaattaggc gttatataca
    11041 atcttcccat tacatattgt ataattaatc ttgccataca aagatttacc tttaaacggt
    11101 gaattatcag ctttagaaac aaaactttca actgtccatt cttcttcagg gttgaatata
    11161 acaatgtccg ctacagcccc ttcttctata aacccagtat ttaaattgta caattttgca
    11221 gggtttgtag acattttttc tattaactgc atcatactaa gatgattttt atgcactaaa
    11281 tttgttattc caagagctaa ggaagtctca agcccaataa ttccacttgg agcttttata
    11341 aattctctat ctttttcttc tctactatga ggcgcatggt ctgttgctat tatttcaata
    11401 gtaccatcat ttaatccctc tataatttta tctctatccc atttacttct taggggtgga
    11461 ttcatttttg catttgttcc aaactccaat acatcttcct ctgtcaatgt aaaatgatgt
    11521 ggtgaagctt ctgcaactac atttgcacct aagtattttg caaatctaac catatcaaca
    11581 gatacacctg aacttatatg ttgtatatca accttagcac cagtctttag tgccaacata
    11641 caatctctag ctaccataac atcttctgct acacttgatg caccttttaa tcctagttct
    11701 gaagctatct ttcctgcatt tacacctgga tttccaacta aagaagggtc ttcttcatga
    11761 aaactaagtg gtacatctaa ctcttttgcc ttaaccattg cctccataat tagattacta
    11821 tccattaaag gtaatccatc atcagtaaac cctggtacac cagctttttt aagagcttcc
    11881 atatcaacta actctttccc ttcaaaacct ttagttatag ctgctgcttg taaaacattt
    11941 atacatgcat tttttgattt ttctttaaca taattaaaag tatcctcatt atctacaata
    12001 ggattagtgt ttgccataca tataacagtt gtaaatccac ctctagcagc agatttagct
    12061 ccactttcta tatcttcttt atatgtaaac ccagggtctc taaagtgtac atgtacatcc
    12121 actaaacctg gagcaactac attaccacta gcatctatta ttttttcata ttcatcactt
    12181 tcatcaaatt tacctatttt ataaatttta ttttctttta taattaagtc aatattctcg
    12241 tctctttgac ttttagggtc tattactcta ccatttttaa ttaaaatcat attatttctc
    12301 ctttatattt ttaatttata tagactcata taatattata cattatttta catacttaaa
    12361 tacaaaatta cgtttgacat caatagcctt tttaggacaa agttcatggc aacagtaaca
    12421 tcttatacat ttgcttaagt ctataatagc acccttagtc cctatttcta tagtagctgc
    12481 aggacaagct tccttgcatt ttccacattt tatacaatct tgaaatctaa ctacaggttt
    12541 tggtgttata agctttgaaa taggctcatt taaaaatttt ggtagcttta cggaaaacaa
    12601 tcttaaatct ttacttacat ttggaacctt gtaatttttt ataattaaat cgtttatatc
    12661 ttcacctaga atttcaatat ctgaaaaatc ttctcgtata taacctctct taatagcacc
    12721 tctaattgta gcaactctgt tgggaattaa acttataatc ttacacgcaa caacgtctat
    12781 agcatatgga ttttgtgatg ctaataaaac tcctatttct ctagtagtgc cagctgaggg
    12841 tccatcacct tccataccta ctataccatc cataattgtc aatgtcggtt ttatataatc
    12901 acaaatatct aaaagtacat tttcacaaaa caactcttct gtaggaaatc tataatgtat
    12961 ttctgctttt tttaatccag ctatacatcc atataagttt tttgtaccac cagtaaaagt
    13021 tgccattata tgagtcttta atttacaaag atttattatg taatctgaat ctactactgg
    13081 tttaataata tccatatatt ttagaacatg tgctttttca ctatgtacct taacatctga
    13141 aacatcataa tttaacttaa tgcccaattc atttgctact tcttcaattc cagatgcctt
    13201 ataaatactc ttaagagaac tttgattata tggaccacca gggctatctg ctattgtaat
    13261 atcacaattc aactctaaaa gtttttcaca tacaactttt acaaccatag gatgtgtagt
    13321 tgtagcttct tcaggctttt ttttcatcaa taaatttggt tttataagta ctttactccc
    13381 ttttttaaca aacttgtcta taccaccaat atcctctaaa tttttttcaa tagataacct
    13441 tacttcttca taattgtaag ttttacaact cctaacagat actgacttca tattatctcc
    13501 atccttctat cacaacagtt tatttgtata atttaaaaaa ggagaaacca aagtttctcc
    13561 ttttaatcta tgttttaatt attattttcc aaaatatctg tttaataatc ctaagaatgc
    13621 tttaccatgt ctagcttcgt ctttacacat ttcatgtact gtatcatgta tagcatctaa
    13681 gcctaactct ttagctctct tagctaattt taattttcca tcagttgcac catattcagc
    13741 atcaactcta actcttaagt tttcttttgt atctgcaact acaacttctc caagaagttc
    13801 tgcaaattta gcagcatgtt cagcttcttc aaaagctatt ctcttataag cttctgctac
    13861 ttctggataa ccttctctat cagcttgtct actcattgct aaatacattc ctacttctgt
    13921 acattcacca gtaaagttcg ctcttaatcc ttcaattatt tctgcatcta caccttgagc
    13981 tactcctatt ctgtgttcat cagcccaaac catttcgcct ttcatttctt caaatttatc
    14041 agctccaact ttacatactg gacattgtgc tggtgcagca tctccttcat gtatatatcc
    14101 acatactgta caaacaaatt ttttcataat taacttcctc ccaattttat ataattaaat
    14161 ttttattttt aagtttaata acttgctaca agaatatata taccccagac tttgtagctt
    14221 aaacactaaa aataaaattt atttcctaat taattttatc actttgaaac aacagtatca
    14281 accaagtttt gatgtcaaat ttctacataa tacataattt atttaattaa ttaggaaata
    14341 attgtaatat taaatacttt ccaatgaaga ctcttctgaa tctttaagct tcactttttt
    14401 gctctttaaa aaagataatt tggtttctgc agttatgatt gcaacaaata tcaagatact
    14461 accaataacc aattttgctg taataagttc ctttagaatt attatagaaa atattgtacc
    14521 aaatacagct tctgtggata atattatagc agttctagtt ccatcaactc ttttttgaca
    14581 tatcgtttga aataaaaatc caattgtagt actaaataca gctaggtaca tagttcccat
    14641 atagccagat aactcagcct ccatctttaa ttgacctgca aatgcttgaa ctatcacaga
    14701 cattaaaaat gctactgtaa attgaatggc tgtcaatgcc attggattat tatcttttgc
    14761 aaactcactc gtaaagaata tatgaaatgc aaatccaaat gaacatataa gtgttagaaa
    14821 atctccaaaa ttaatagaga aatcagcttc taaagaaagt atcccaattc ctataagagc
    14881 taccaagcta cttattatcc ctatcttatc aagttttctt ctataaagta taaatcctat
    14941 gaatggaact attacaacat tagctgctgt tataaacgca ttcttagatg gtgtagtgta
    15001 cataagtcca atagtttgta cggtgaaggc tagaaataaa aatattccta aaatccctcc
    15061 tgcttttaat aattttttac ccatattggc acgaatctgt ttaaaaaaca gtaaattcat
    15121 aattatagct gccaagaaaa atcttaaagt tataatttgt agaggtgtaa gcccaccgtc
    15181 taatgcaaat tgggttgcta caaagccact tccccatata attgctataa atattagtcc
    15241 tatttctcca aagtattttt tcaataaagc cccctccttt ttattttttt gcaaaattat
    15301 aaacccccta aacagcaaga gagtttttct ataagcatta ctataaatta atatagtaaa
    15361 ttttttcagt attttaaatc taaatttaca tatattttga gctcaaattt atatccacca
    15421 tttaacagta atatattaat cattttttgt aaacaccttt ttgataaatt tttttgtttt
    15481 ttatattttt ttacctatac taaatttttt tatagataaa tttgatatat gtgatacttt
    15541 aatattatgc aaataatgtc atataagtta cactttagtt atcttagtta caactttgtc
    15601 ggtttacttt ttctactttc ttcgatataa ttataatata tttttgatac aattcgacaa
    15661 aagggggaat gctgtaatta tggtaaaaaa aagaaaaaag aaaactgttg cacttactat
    15721 aattgttgta atagttattg gtattttttc tatggcatgg gcggacatgt ctagaaaaaa
    15781 agaaatgaaa gaaactcaag aaagacttaa agctgaaaga ttagaaaaag aaagaattga
    15841 aaaagaaaaa aatgaaccta ttattggtgc aaaaaaagaa gctataaaag aatatggata
    15901 tgatgcaaaa atagtttggg acaaacttaa caaatacgac tattcaaaca acggagaaaa
    15961 gatagtcttt cttacatttg atgatggacc atctactact aatactccac aagttctaga
    16021 tatcttaaaa agacatggtg ttagaggaac tttctttatt aaaggtgatt ctcttgaaag
    16081 aaaaggcgct aatgaaattt taaaaagaac atttgacgag ggaaatgcaa tagcccatca
    16141 ctcttatact catgactata aaaaactata tcctggcaga agtctaaatc tcgatacatt
    16201 cgtaaatgaa cttaacaaaa ctgatgaagc tatgaaaaaa gtcttaggaa agaatttttc
    16261 ctcaaatgtg gttagatgcc caggtggtta tatgtcatgg aaaaatatgg aacccctagg
    16321 aaactactta aaagagaaaa acatggcatc aattgattgg aatgctttaa atgctgatgc
    16381 agaaggtaaa aagaaaaatg cacaagaatt atttgaacat gcaaagaaat cttctgaagg
    16441 caaagaaatg gttgttcttt taatgcatga tacttatgga aaacaagaaa cagtaaatgc
    16501 attggaccaa attataacgt attttaaaga caatggttat caatttaaaa ttttaatata
    16561 gtaaaaaagc aagtttattg agtatacatt ttatactcaa taaacttgct tttactttac
    16621 tctattttac tagctctatt tttacaaatt ttttctttcc tatttgaaca actaattcac
    16681 tttcttttac aatagtgctt aagtcctcta ctttttcacc atttaccttt acgccacctt
    16741 gagaagctaa tcttctaact tcactcttac tcttaacaat ttcattaaca actagtactt
    16801 cgattaagtc aaatccatct tccttaactt gaattgtttg tatatcttca ggtatttgac
    16861 ctttttggaa tacagattta aatctttctt cagcttctct agcagattct tctccatgat
    16921 ataatgttac tatttctctt gctaagttca tctttatatc tcttggattt acagaaccat
    16981 cttttaattg agattctatt ttgttaactt catcaggatg aacatctgtt actaaattgt
    17041 agtatttaat tataagttca tcaggaattt ccatagattt ttggtacatt attcccgctt
    17101 cttcatctat tccaatatag ttacctaaac tcttactcat tttttctttt ccatctaatc
    17161 cttctattaa aggcatcatt attactattt gagactccat accaaattct ctttgtaacg
    17221 atcttcccat taataagttg aatctttggt cagttccacc aagttctata tccgcttcta
    17281 atgctataga atcatatgct tgcattaatg gatagaaaaa ctcatgtact gatattggca
    17341 tttgtccttc atatctcttt ttaaaatctt ctctttctaa cattctcgca acagtaatag
    17401 ttgctgctaa ttttattaca tcttcaaaat ttaacttagc taaccactca ctattaaatc
    17461 ttacaatagt tttttcttta tctaaaactt tgaaaatttg ttcttcataa gtttttgcat
    17521 ttgcaagaac ttgctctgtt gttaaagctt ttctagcttt agactttcca gttggatctc
    17581 caatttttcc tgtaaagtct ccaattatta ttactatttg atgacctaaa tcttgtaatt
    17641 gtttcatctt tctaagaact actgtatgcc ctaaatgtat atctggagca cttgggtcta
    17701 gacccaattt tactatcata ggctttcctt ctttttctga tttaataagt ttttccctta
    17761 actctttctc atctattaaa tcatctacac ctttcataat tattcgcatt tgctcgtcta
    17821 tcgatttcat ttttcattcc tcctaaaata tttatataat ctataatttt tatttttata
    17881 ataaaaaaag ctttcatcct attaaaagga cgaaagcatt gcttacgtgt taccacctta
    17941 gttcatcaat atctcacgat attaatctct tagagtataa tggcatatac tcgtgtacta
    18001 taacgtgtac tactccgata tctcttaatg gttgttatct ttcagagata gtgctctgag
    18061 atgtattcaa actaaatcaa tttattccat ttcaccaaac tggaactctc tgttaaataa
    18121 aatctagctc tacttcttct cttcatagca tttatatatt cagattattt catcaattac
    18181 aagaaatttt tcttaactta ctcataatat attattattt ttctattttg tcaacctttt
    18241 tattattata tacatgtttt tttacattat actacttttt tatatttttt accaatacct
    18301 aaagtttatt tttcaatcaa aagatttatc tgtttattga ctatattgtt ctgactcaat
    18361 cttatattta ttttcttatt taaaaatgca tttataatta ttaaactaat gactgttaca
    18421 tcaaacataa aaaacaacaa taaaattatt attaaaaaag aaattctagc atataataat
    18481 tttctaaact tagctattat aaaattttgt aatgacatac atgagtctct aataataaaa
    18541 tagacacata aatacgctat tgatatgaag actgttttta aataaacaaa atcaacttta
    18601 acgttcaaca gctttacaac ttcaaaaatg gttagataag aaacacatat gtaaaaaact
    18661 ttctttgaac aacataaaaa ttgatttaaa gttctaaaat tcttaaatat taaaagcttt
    18721 tttaaagaat tagaatctaa aatatgcaat ttattcccta aaatcaaact taataaatat
    18781 atgcaaaaca ccataccaaa aggaaacaat gctatcatta aataataaat aaaatttgta
    18841 tacccattaa aataaatcca tttgctatat ccttgaaatt ctttcataaa actataacct
    18901 attaatgttg aagcatatat atcaataaaa accattacaa taactccaaa cactgatcca
    18961 tatactaaat catccataac cattgtaggc ttatttatta gatagccaca cattatacca
    19021 agtaatacac tctgagttgc ccaaatagca gttcctaaat ttccaagtac cagagaaatt
    19081 attaaaagtg aagttattcc agataaaatt gtatacttta aatcacattt caagcaaatt
    19141 atacaaaaaa atattggcac tataaaatct aaataaatag catatccaaa tccagtactc
    19201 acagatataa ttgttactac tatgaataaa gatgacaata aagctgcttc agttaatttt
    19261 ttagtagtat tcaaaacgct acctccataa atcataaatt ttctaactaa agttttgttt
    19321 ttaatatagt atatcacttt ttaaaaatat ttttaataaa tataaatttt aataaaggta
    19381 tttatgttaa aaatgatata atgtatctta atattcagtt ttttaagata ctaggaggta
    19441 attattatgt ttaaaattaa acactttaat gatttaaatt tagatgaatt ttatgaaata
    19501 gcaaaatcaa gatatgaagt atttgcttgt gaacagaaga tattttcgtt aaacgattat
    19561 gatgatatag ataaaaactc ttatcatata ttcttaaagg aaaatggatt gatttgtgct
    19621 tatgctagaa taattcctaa agaatacagc tcttataatg atgtttccat tggtagagtt
    19681 ttagttcttt ctcgtcatag aagaaaaggt ttagcaaaac aaatgatgga ttgtgctata
    19741 gattttataa aagttaactt acacgaaaac aatataacct tatcagcaca aacttatata
    19801 aagaaccttt acttatcttg tggttttaaa gaaatctcag aagtatacga cgaagcaggt
    19861 attgaacata ttaaaatgag attatagtgt tgacaagcta atattgttaa tatataattt
    19921 aattataaat taaatattga attgatattt aggtatttga aaatacctta catagagtca
    19981 ggaggctttt gctttctggc ttttttatta tcaaaattca ataattatat ggattcaaag
    20041 tgttaatttt tattctatat tctactttcc ccaaaagtaa gaattatacc caactttgta
    20101 tgataggcat cttgcctatc ttttttttgt aaaagtaaca aggtgataat ataatgcata
    20161 gtttagaata agaagattag cccaggctaa attccaagca tggaggtgct actatgaaaa
    20221 accttaacga tattcaagtg aaaaaaactg tcaaagttga agatatatta tctagtggta
    20281 atttaagaga aagaatgtta gcgcttggtc ttactagagg agctgttata gatgtagtta
    20341 gaaaaggtcc aaaaaataat ttaactgtct ataaaatcag aggtagtaag atagctctac
    20401 gacaagaaga aagtagctta atattagtct ctgacattta aaaatttcta gcaggaggat
    20461 attaatatgg ggttaacaca taactcaact aaaatgagtt ctttaaaaga tatgtttgat
    20521 atagacaaca aagaagacca gtttgtaatt gcattggctg gtaatccaaa tacaggtaaa
    20581 agtactgtat ttaatcatct tacaggactt agacagcata ctggaaactg gccaggaaaa
    20641 actgtagcta cagctcgtgg taattttaaa cataaaaata ccgaatatgc attaatagat
    20701 ttaccaggaa catattcttt atttgcctta tcacaggaag agattgtagc tcgcgatttt
    20761 atatgttttg gtaatccaga tgcagtaata gtagtatgtg atgctacatg tcttgaaaga
    20821 aatttaaatt tagtatttca agtgatggaa cttacagata aagttatttt atgcattaat
    20881 ttaatagatg aagctataaa aaaaggcatt actattgata aaaaacttct agaggattct
    20941 ctttgcattc cagttattct aactgctgca agaaacgggt ctggtatgga tgagctattg
    21001 gatactttaa atgatgtatc ttttgacaaa tacaaattaa ataataagcc tgttagatac
    21061 aatgaaaata tagagaatgt ggtaaaatca attcaaccag aattggataa tattataccg
    21121 ggtataaatt ctagatggtt gggacttaga cttattgatg gtgatgaaag tatatttgaa
    21181 tctatgagta attatataga caaagattcc atagatgcta ttaatgaagt aaagaaaaag
    21241 attccagata atataaataa acagaaaata agagatgagt ttaccaaaat caactatgat
    21301 tatgctaaaa aactgagtga tgagtgttgt tctaatgttg ctaaaaaatc aactgataga
    21361 gaagaaaaag tagataaaat attaacatct aaaatatttg gacttccaat aatgctctta
    21421 ttattaggaa ccatattgtg gattaccata gaaggtgcta actatccatc cactttattg
    21481 tctaatttgt tactcggatt tgagccaagt atttcgggta tattaaatag tattaattgt
    21541 ccatcatggt taaatgatat gttggtttta ggattataca gaacattagc atgggtaatt
    21601 tctgtaatgc tacctcctat ggcaatattt ttcccattat ttaccttact cgaggatttt
    21661 ggatatttgc caagagttgc atttaactta gaccacctat ttaaaaaagc ttgtgcacat
    21721 ggaaaacagt gcttgactat gtgtatggga tttggatgta atgcagctgg agttattggt
    21781 tgtaggataa ttgactctcc aagggaaaga cttatagcta tacttacaaa caactttgtt
    21841 ccttgtaatg gtcgttttcc tactttgata gctatatcta caatattttt tagctcagtt
    21901 ataaccaact ctttcgtatc aagcgtagca actgcacttt gcataacttt actgataatt
    21961 ctaggtgtta taataacatt attagtttct tatactcttt ctaagacact attaaaagga
    22021 gttccatcta cgtttacatt agaacttcca ccttatagag ttcctcaaat aggaagaact
    22081 ttatatactt ctataataga tagaacaata tttgttttag gaagagctgt aatggtagcc
    22141 atacctgctg gtgtcataac ttggatattt gcaaatatat atataggaga tttaagcata
    22201 ttatcacatg ttgcaaactt tttagaccct ttagctaagt taattggtct tgatggtttt
    22261 atattacttg cttttattct tggattccca gcaaatgaga tagttgtacc tatactttta
    22321 atggcttacc tagcaactgg ttctatgata gaattagata gctttagtgc tttaggtcaa
    22381 gttcttagag aacatggatg gacttatttg acagctttaa atgttatgct gttcagttta
    22441 ctacattggc cttgtgcaac aacactttta acaataaaaa aggaaactgg tagtttaaaa
    22501 tggactgcct taggattctt aatgcctact atacttgctt ttgttgtttg ttttttaaca
    22561 actacagttt acaatttatt tatataatta acattaactg acattagaca tatattagaa
    22621 tactttatta taaagcatag agatatattc aatgataagt aaaattactt agtatttgga
    22681 tatatctcta ttttaactct tatctggaca cttggattga aatttcagtc atataattat
    22741 cttcattact ttcacaaaaa aagtcaagta tactctcttc atatgaattt ccaataattt
    22801 tatattcatt ttcatatata tattttttca atttttcata agatttatat gaattctcat
    22861 actttccaat atgctttatg caagcataca ttccttctgg ctttatatat aaccttttat
    22921 cctttatttt tttatctatc ttcaaataaa aacttgatat acttaaatag tccccatttt
    22981 ttaggttttc attacttact attactccta actcatatcc ttgatataaa ttcttcgctt
    23041 tacaataatt ggtgaaatct attaattcca tcataaaatc accattactc atattactca
    23101 aatcacttga taaaactaaa tattcttcag actttttgga tatataaatt tcttcactat
    23161 tcattttaga aattccttcg actgttatat ttattctatt ttgcatctta gaacttatct
    23221 ttcgtaattt ttttattttt tctcttatct ttttttcttc ttctttaagc attttcacac
    23281 aaagctgagg agttctattt tgtatatact cttttatttc ctctaaactc attcctattt
    23341 ctcttaatga ttgtaatata tccaatgtat catattgata aactgagtaa tatctataat
    23401 tatttttatc tttatattca ggagaaaaaa tccctatttt atcatagaaa attaatgtct
    23461 gtttagatat accacacaat ttagcaaatt cacctgttgt aaaatactgt ttttccaagg
    23521 gttatgcact ccttttattt ttattatata tatagttact atatacttta gtatttacta
    23581 aatcaagtag ttattatttt agaaaatcaa tatgtttttg attttaaaga ttaaatgtca
    23641 gttaaatatt ttatccatcc cagtaataaa aaatatacac cctctgaact tttagatatt
    23701 atatttatgc ttgttagagc ggaaattgta aattgtatct acctcttact attttattta
    23761 tgatatatta ctttttaatc taaaaagaga tatctatttt tattctagtt atctcttttt
    23821 agattccttt aagcatatga atattccaat ttaacaccta ttgaagtgct attttcttat
    23881 atcacaattt ataattgata tatcttcaat ataataatct aatgtatttt tgattttaaa
    23941 gcttttcagt aatattattg ataaattaga attaattatc tagctttaaa aggtcaaaaa
    24001 tttcagttgc cgtctgtggt tttccaaata aatatccttg tatgtaatct ggcttcattt
    24061 gtttaactaa atcatactct tcttgtgttt ctacaccttc taaacatact tttattccta
    24121 catcatgaca aattgcaaca ataaaatgta taaatgtagc atcaaactta ctctttaata
    24181 tatctttaac aaatactcta tcaattttca ctacatctat tggagaaaat tttaaaactt
    24241 ctaaagacga atatccagta ccaaaatcat ccatagcaat ataaattccc aaatcttgta
    24301 aagccttaaa cttaaactgt aaaatactca tattttgtac tgtatgactt tctgtcaatt
    24361 ctaaaacaag attttgataa ggaaactttt catcatctat gatttttact atatcttcaa
    24421 taaatgtatc ttctaatatt tgaacagctg aaacgtttac actcacttta aaaaaaggat
    24481 aataatcaat taatccctta aaagtacgta acgccattct aagcacccat gctcctacag
    24541 tatttatcat atcatgttct tctaatattg gaataaattc taagggagaa attgctttat
    24601 atttatcatt agtccatctt aaaaggactt ctacacctat tattttatga ctttgtgtat
    24661 ctacttgtgg ctggaatcga agactaaatc ccctaaaatc atcattaatt gatgctttta
    24721 aatcccgcat catttctaat gaatacattt tattttttaa tatttcttgt gagaaaaaaa
    24781 caagcctgtt tttaccatgc tcttttgcat attgtaaaga gtaactagca tatttataaa
    24841 gttcttttac tgtatctccg tgctttggat atattacaca accagcagaa attgttatat
    24901 ttaatccata ttttctccat agttgaaggt gtataatcat attctgtatt tgattgtata
    24961 aagttagaat ttctttttct tcaacattat caacaataat tcccatttca tctccatcaa
    25021 gtttataaag ttcagcatta tctggtaata tagattgtat agactgtgct agtgttttta
    25081 ttatattatc tccaaaatct ctatcataca tctcattaac atttttaaaa tcatcaatat
    25141 ttaataatac tatgcataat ttttcaatca taggatttga aattttatct tcaaatacac
    25201 tcataaattc atgatagttc aataactgtg ttaatgaatc aatcttattt tgtttaccta
    25261 attgtgtcat tattcctgca aaaatacttg gttttccaaa ttcatcacgc attagttgcc
    25321 ctctacatct taaccatata tattctccac tgcgattttt agccctaaat tccactgtat
    25381 gatagtccat ctggttttta cctatttcag tatttgactt ataaaaacgt ttccagtctt
    25441 ctggatgtac aattttttcc cagtaaataa gaggattttc aacaatttct cctggtaagt
    25501 caaataattc aacttgtgat ggtgaatatc gaaatactcc tgttttcata ttacaaatat
    25561 atatatattc atctgtacct ctaatcaaag catcataaag caatgtagaa ttataatcaa
    25621 aattgtctat tgagacatta aaaactcctt tttcttcttc agtatttgat attttatgaa
    25681 attcattagg cttaatttgt ttatttaagc ttgttgagtt tgtaatatct attgattggt
    25741 gcatatgaac aactgtgcca tcttgccatg taattaaact atcataattt tcaaaaacac
    25801 aatttagctt attacatttt tcataccatt ttattaatac tcctttttta tcattcttta
    25861 acaattctac aactttacaa aaactacaag tagaattttt ttcaggatat aatacttgcc
    25921 aacaaacttt tccttctgga tctaaaatgt tatattcttc tttcattttt ttattcataa
    25981 aaacaatttc attagtatga atattcgtaa catatatgtt aatctgtagt tgatttaata
    26041 taacttcaaa a
//
LOCUS       DBGJFK010000053        23685 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.053, whole genome shotgun sequence.
ACCESSION   DBGJFK010000053 DBGJFK010000000
VERSION     DBGJFK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23685
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.053"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            178..780
                     /locus_tag="ACOIAP_002511"
     CDS             178..780
                     /locus_tag="ACOIAP_002511"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639393.1"
                     /translation="MIKKENIRKILIIGTSKKMVNQIVDRLSIGRVCKFINIEDISTK
                     YEIEVAKQSRKEGNHVIPVPAVEIKSMASGLSINSLKRLFRKGNNRNMVVLEKTIIRP
                     TFSYIGKFYISADVIKQIIEYEVYSFGSIDRINKINIENCNNFMNIFVSININDLETI
                     KKIEDIQQIIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            908..2173
                     /gene="gluD"
                     /locus_tag="ACOIAP_002512"
     CDS             908..2173
                     /gene="gluD"
                     /locus_tag="ACOIAP_002512"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HGZ2639394.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            2674..3813
                     /locus_tag="ACOIAP_002513"
     CDS             2674..3813
                     /locus_tag="ACOIAP_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HGZ2639395.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKDININNINLEGFNNISTVISSILLYTWITSVVIY
                     LIYTIFKYIKLKNLISDLSYEVDDEEIINLYRSILKEFDITKDIKLKYSYEVETPAFF
                     NSCVLLPPHDYKLKELDWIFRHELMHFKSKDLYLKYVILFLKIVYWFNPFVYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTIINAMRKGTNTSNKFIAGLHKQSDIKKRVKN
                     MFNEKYKNGILMALTLCLLSSITFLKVNTTSVINFNVLPKGLEDAHVIGSITVTTIEF
                     TYADAPKNVREEHKRNCEELGVIPKDSDQIGVGVEYYNSLSKRSR"
     gene            4272..5294
                     /locus_tag="ACOIAP_002514"
     CDS             4272..5294
                     /locus_tag="ACOIAP_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HGZ2639396.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEENGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQINPSVNQNVDSTNTNQQNNANTSQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVRVTSINSAYYTARFV
                     TAKRIL"
     gene            5589..6509
                     /gene="pyrB"
                     /locus_tag="ACOIAP_002515"
     CDS             5589..6509
                     /gene="pyrB"
                     /locus_tag="ACOIAP_002515"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HGZ2639397.1"
                     /translation="MLESRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMKIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLENHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDG
                     DDRAVYFKQAKYGMYVRMALIIKLLGISED"
     gene            6548..7240
                     /locus_tag="ACOIAP_002516"
     CDS             6548..7240
                     /locus_tag="ACOIAP_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGZ2639398.1"
                     /translation="MYKILENIYIGEDMYRMKVKGTFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEEEYKQVCNEVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNEGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            7233..8135
                     /locus_tag="ACOIAP_002517"
     CDS             7233..8135
                     /locus_tag="ACOIAP_002517"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGZ2639399.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDNELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVEMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            8220..8804
                     /gene="pyrE"
                     /locus_tag="ACOIAP_002518"
     CDS             8220..8804
                     /gene="pyrE"
                     /locus_tag="ACOIAP_002518"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0019856 - pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGZ2639400.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            9021..9947
                     /locus_tag="ACOIAP_002519"
     CDS             9021..9947
                     /locus_tag="ACOIAP_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HGZ2639401.1"
                     /translation="MKNQLNKSQKKVVFFGVGAVGATFAEQFLNSKYDFKILCNKERK
                     KRYLEDGFIINGKRYDFDYVTRDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYVLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKGISLTEDDVENSLHRILEHSKEGRTSMLQDVEAHRPTEVDMF
                     SKNICKLGKKYSIPTPINQTFFYMIKVIESRF"
     gene            complement(9998..10888)
                     /locus_tag="ACOIAP_002520"
     CDS             complement(9998..10888)
                     /locus_tag="ACOIAP_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2639402.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSQKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQDQKWIVREDGSGTRDYLDMFLSVKEIIPRSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            11076..12107
                     /locus_tag="ACOIAP_002521"
     CDS             11076..12107
                     /locus_tag="ACOIAP_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HGZ2639403.1"
                     /translation="MLKKKSILTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKILRVIFLVVVVLVFGHMKNQSNKEILEEEKDEIKKKKVTIPWYVIGFFVTCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFIGIVQVVS
                     AVVLIKIFI"
     gene            12401..13276
                     /locus_tag="ACOIAP_002522"
     CDS             12401..13276
                     /locus_tag="ACOIAP_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HGZ2639404.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGKEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDKVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            13294..14784
                     /gene="cls"
                     /locus_tag="ACOIAP_002523"
     CDS             13294..14784
                     /gene="cls"
                     /locus_tag="ACOIAP_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGZ2639405.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGIGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNIGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTEDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            14977..15261
                     /gene="groES"
                     /locus_tag="ACOIAP_002524"
     CDS             14977..15261
                     /gene="groES"
                     /locus_tag="ACOIAP_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGZ2639406.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            15294..16922
                     /gene="groL"
                     /locus_tag="ACOIAP_002525"
     CDS             15294..16922
                     /gene="groL"
                     /locus_tag="ACOIAP_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGZ2639407.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEERVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVIKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            17184..17924
                     /gene="larB"
                     /locus_tag="ACOIAP_002526"
     CDS             17184..17924
                     /gene="larB"
                     /locus_tag="ACOIAP_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HGZ2639408.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYSHAEYEDLSK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLAAMINKL"
     gene            18059..19191
                     /gene="larC"
                     /locus_tag="ACOIAP_002527"
                     /pseudo
     CDS             18059..19191
                     /gene="larC"
                     /locus_tag="ACOIAP_002527"
                     /inference="COORDINATES: protein motif:HMM:NF014072.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
     regulatory      19251..19352
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19573..21108
                     /gene="guaA"
                     /locus_tag="ACOIAP_002528"
     CDS             19573..21108
                     /gene="guaA"
                     /locus_tag="ACOIAP_002528"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGZ2639409.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIETVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            21454..21864
                     /locus_tag="ACOIAP_002529"
     CDS             21454..21864
                     /locus_tag="ACOIAP_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639410.1"
                     /translation="MGKINSYNKEMESILIFDIGGISVKNTFSEVKLFQVKPDRLDDF
                     EKLIVLVAEEQKQQTGCIDIKYLKRFYIFDNIKEQPRELTKIVKCVKYYSYWEFDTLE
                     NYSNATHWFFDTYSKEVFKLLIMPFDINCGNSIY"
     gene            22098..22289
                     /locus_tag="ACOIAP_002530"
     CDS             22098..22289
                     /locus_tag="ACOIAP_002530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639411.1"
                     /translation="MLKLCFIIGIMLSIQTVFQLVNKIEIPVPALITKVLIFVVLAVF
                     ARYIERNLKGNFIYSNSDF"
     gene            complement(22328..22900)
                     /locus_tag="ACOIAP_002531"
     CDS             complement(22328..22900)
                     /locus_tag="ACOIAP_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639412.1"
                     /translation="MINGDKISLIPATLDDRQKVYEWCFQSETTKSHSGLPNYPNIPI
                     ATYEEFCEEDYEEYFFTGAKPKDGRGFLIVSNTEPVGFISYSCFHLKQALAEIDIWMN
                     CEANCGKGFGVDAIISLGDFLNKTMDICELIIAPSRKNIRAVKAYKKAGFKPSTKPMS
                     DYLLDKYIPLYGTGDYGIDETVILVKQLDT"
     gene            23361..23567
                     /locus_tag="ACOIAP_002532"
     CDS             23361..23567
                     /locus_tag="ACOIAP_002532"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639413.1"
                     /translation="MKNKIIIGITFSLVLLMSGCVSKQTAEINVLATTDLHGVIPYEL
                     TSYVKEERKKDKNLTLVDAGDFFD"
BASE COUNT         9346 a         2463 c         4321 g         7555 t
ORIGIN      
        1 gcaaaattct atgaagcagg aaccctgtga ctttagtcat gggaggttca ggatggaatt
       61 ttaatataca aaaacaaggt tttagctgga gtatcagcaa aacaagcaaa tactactata
      121 gaagcagtta aaagggctat tttttataat ctggagcata gacaagaagt tagagaaatg
      181 attaaaaaag aaaatataag aaaaattctt attattggaa catcaaaaaa gatggttaat
      241 caaattgtag atagattgtc aattggaagg gtttgtaagt ttataaatat agaagatata
      301 agtactaaat atgaaataga agtagcaaaa caatctagaa aagaaggaaa tcatgtaatt
      361 cctgttccag cagttgagat aaaaagtatg gcaagtggtc ttagtataaa ttctttgaag
      421 agacttttta ggaaaggaaa taataggaat atggtagttt tagaaaaaac aattataaga
      481 ccaaccttta gttatatagg aaagttttat attagtgctg atgtaattaa acagattatt
      541 gaatatgaag tatacagctt tggtagcatt gatagaataa ataaaatcaa tatagagaat
      601 tgcaataatt ttatgaatat ttttgtaagt ataaatatca atgatttaga aactataaaa
      661 aaaattgaag atatacagca gataataaaa aagtctattg agaaaatgac tttagttaat
      721 gtacaaaaaa tagatattaa cattcataaa attaaaaaaa taaacttcct ccaatgttaa
      781 aaaataaact gagaaaatga tatactaatt tgcaataaag tgtgctataa ttaaactgta
      841 aatttaggaa atggtttttc taaatggagt atacataatt ataacgtatt tataaggggg
      901 ctttcaaatg tcaggaaaag atgtaaatgt cttcgagatg gcgcaatctc aagtaaaaaa
      961 tgcatgtgat aaattaggta tggaaccagc agtttatgaa ttattaaaag aacctatgag
     1021 agttatagag gtttcaattc cagtaaaaat ggatgatggt tctataaaaa cttttaaagg
     1081 atttagatca caacataatg atgcagtagg gccaacaaaa ggtggaataa gattccatca
     1141 aaatgtttca agagacgaag taaaagcttt atctatatgg atgactttca aatgttctgt
     1201 aacaggtata ccatatggtg gaggtaaagg tggaataata gtagatccat caactttatc
     1261 tcaaggtgaa ttagaaagat taagtagagg atatatagat ggaatatata aattaatagg
     1321 tgagaaagtt gacgttcctg caccagacgt aaatactaat ggacaaataa tgtcttggat
     1381 ggttgatgag tacaataaat taactggaca aagttctata ggtgttataa ctggtaagcc
     1441 agttgaattt ggtggttctt taggaagaac agctgctact ggatttgggg ttgctgttac
     1501 tgcaagagaa gctgctgcta aattaggaat agatatgaaa aaagctaaaa tagctgttca
     1561 aggtatagga aacgttggtt cttatacagt tcttaactgt gaaaaacttg gtggtactgt
     1621 tgtagctatg gctgaatggt gcaaatcaga aggttcttat gctatataca atgaaaatgg
     1681 tttagatggt caagctatgt tagattatat gaaagaacat ggtaacctat taaacttccc
     1741 aggagctaag agaatatctt tagaagagtt ctgggcttca gatgttgata tagtaatacc
     1801 agctgcatta gaaaactcta taactaaaga agttgctgaa tctataaaag ctaaattagt
     1861 ttgtgaggct gctaatggac caactactcc agaggctgat gaagtatttg ctgaaagagg
     1921 aatcgttctt actccagata tattaactaa tgctggtgga gttacagttt cttacttcga
     1981 gtgggtacaa aacttatatg gatactactg gtcagaagaa gaagtagagc aaaaagaaga
     2041 aatagctatg gttaaagcat ttgaatctat ttggaaaatc aaagaagagt acaatgttac
     2101 aatgagagaa gctgcttaca tgcattcaat taagaaagtt gctgaagcta tgaaattaag
     2161 aggatggtac taggatttac tcttaataaa taataggata taattattta agatataaag
     2221 gggctgtaca tagtacagcc cttaaattat gtggctcagg taatgtgagc cattttttat
     2281 tttaatttat aaattatata actcaaaatt taaaacgcta taagtaagac gagtgataat
     2341 ttatggttaa tttaatttta agtaggcttt ttagaactat tctagtgaat agtttatgta
     2401 ttcttttaat attagcattt aagaaaagta tttttgttct attttaactt tgcttttata
     2461 tatttataac tgtcaaagtt atatggagtt aaattaattg atgatgttta atgcacagta
     2521 atcattacta agctataatt aactataaga taataaaaca tagttattta ttacagaaaa
     2581 tatatatttt aattaataaa tatgatatga aagtgttaag agataactaa aattaactat
     2641 aaaacactat taaataagat aggggaaaaa catatgtcta attttattct aaatgggatt
     2701 tttagaactg ttatagtgag tagtttaagt attcttatga tattaatatt caagaaaaat
     2761 gtgtttaaaa gatttagtaa aaaatttaac tattatatat ggatgatagt tgttattaaa
     2821 ttatttctac catttacata ttatactttt acaataaata tattaagaag caaaaaagac
     2881 attaatatta ataacataaa cttagaggga tttaataata tctcaactgt aattagtagt
     2941 attttactgt acacttggat tacatctgta gtaatatatt taatttatac tatattcaaa
     3001 tatataaaac ttaaaaattt aataagtgat ttatcttatg aagttgatga tgaagaaata
     3061 ataaatcttt atagaagtat attaaaagaa tttgatataa caaaagatat aaaactaaaa
     3121 tactcatatg aagttgaaac accagcattt tttaattcat gtgtgctttt gcctccacat
     3181 gattataaat tgaaagaatt agattggatt tttaggcatg agctaatgca ttttaagagc
     3241 aaagatcttt atttaaaata tgtaatttta tttttaaaaa tagtatattg gtttaatcca
     3301 tttgtatata taatggataa acatatagat ttagattgtg agctttattg tgatgaacgc
     3361 gttttaaaaa atagaaactc agaggaaaaa aaagattacg ctttgacgat tataaatgcc
     3421 atgagaaaag gaacaaatac ttcaaataaa tttatagctg gtctacataa gcaatctgat
     3481 attaaaaaga gagtaaagaa tatgtttaat gaaaaatata agaatggtat attgatggca
     3541 ttaaccttat gtctgttatc ttctattact tttttgaaag ttaatacaac tagtgttatt
     3601 aattttaatg tattacctaa aggcttggaa gatgcacatg ttattggtag tataactgtt
     3661 acgacgatag aatttacata tgcagatgct cctaaaaatg tgagagaaga acataaaaga
     3721 aattgtgaag aactaggagt gattcctaaa gactctgacc aaataggtgt tggtgtagag
     3781 tattataaca gtttatcaaa acgatcaaga tagtaatatt ttaatagatt gtaatttata
     3841 atagttataa agttttaaac agttatttat taagaaaaaa tatattttta taaatgtata
     3901 tacaaaatca caaaatgact aactttatag ttattccctc aaaaaacata tgccacatag
     3961 aaacgcataa aaaaacacat aaaacaatat ttatgcgtac tttagcctct aaaggtacaa
     4021 aattctttac ttttacagac tcgtattata taattaagta aataatgtat atttaggtga
     4081 catattggat aaactaattt atttatttta ttaatattat aatactataa aagttatata
     4141 aagtggttta caaaaaagtt acagatagag cttttattaa tgtattgtgt attagtattt
     4201 tatccttagg tacacttcac ctacaaaata gaatcataag ataattatgg gaaaatttta
     4261 ggaggtttat cgtgaagaaa aagatattaa taccagtatt tgcatcagtt atggcattat
     4321 cagtaagttc aattgtaaat gcagatgaag taaatgattc atctcaaaat aaggatgata
     4381 aaacaaatac tgaattaaat ttaggtgaat ataaagaagt aaaatataaa gttgcaaaaa
     4441 taaaagatgg agtagctata aagataagag aagaaggtca agttcaaaat atagcttatt
     4501 ctggagatga gtttactgtt ctaggaactc aaggagaatg ggttaaggtt aaagttgaag
     4561 atggcgaagg ttggttagct actagatatg tagatatatc tgaaggtgta ggatatacta
     4621 acgctgataa agtaaattta agaaaagata agagtgaaag ttcagaagta attgaagagc
     4681 tagaaaaagg aagctcttta ttggtcttgg aagaaaatgg agattggtta aaagttaaag
     4741 atggggaaac cgaaggatat gtaaaatcat cttatatatc tgataaagct cctgtaatag
     4801 aagagccaca aataaaccca agtgttaatc aaaatgtaga ttctacaaat actaatcaac
     4861 aaaacaatgc aaatactagt caacaaaaca ataattcaaa tgtgccaaca gctaactcta
     4921 atgcagttca agctgtactt aatttggcat attctaagca aggttgccca tatgtttggg
     4981 gagcagaagg accaaacact tttgactgtt ctggatttac acaatatgtg tatagaaatg
     5041 cagtaggaaa gaatatacca agaacatcta aagcacagtc taaatatgga caaactgtaa
     5101 gtaaagcaaa tttacaacca ggagacttag tattcttcac aactaatggt tctggttctg
     5161 ttagtcatgt tggaatatat gtaggtgggg gtaatatgat acattcacca tcaacaggaa
     5221 aaacagttcg tgtaactagt ataaattcag catactatac agcaagattt gttacagcaa
     5281 aaagaatatt ataatcagtt tgtaatatga caaattgata aatacataaa tatatataaa
     5341 cgctctatat tatatttaat ttaatcatgg aaataaaaaa tgattatatt ttaaatgtac
     5401 tatagagcgt ttttgtatca ctttaaatct aatcaggatt cagggtgata ttactttaaa
     5461 taggagcatt ttcatatgat gattatttgc gcaatccctt gacaggatag ggcaaaggtg
     5521 gtaagctact aacagtacaa aaatactttt aattttagtt cagagaggct aaaaaaggag
     5581 gacgaaagat gttagaatca agaaatttaa tccaaccaga agacttttca atagaagaaa
     5641 tagatgaaat attagagtta gctcaaaaga taattgacaa tccgtcaaaa tattctcgta
     5701 tatgtgaagg aaaactatta gctacattat tttatgaacc atcaacaaga actagattaa
     5761 gctttgaatc tgctatgaac agactaggag gtcgtgtagt aggcttttca gagccaaatt
     5821 catcttctgc atcaaaaggt gaaaccctag gtgatacaat gaagatagta tctggttatg
     5881 ttgatataat agctatgaga catcctcaat caggtgcagc atcagaagca gctagatata
     5941 cagaagtgcc atttataaat gcaggagatg gcaaaaatca gcatccaact caaacactta
     6001 cagacttact tactataaaa tcattaaaag gaactttaga aaaccataca ataggattat
     6061 gtggtgattt aaaatatgga agaactgtgc attctttggt taaggctatg gcaagatata
     6121 aaaatacaaa gtttgtattt atagcaccag aagagttaaa aatgccagat tatataaaag
     6181 aagctataaa gggacatgca tattatgaaa ctaataattt ggatgatgtt ataggaagct
     6241 tggatgtttt atatatgact agagttcaac aagaaagatt tgaagataaa tcagaatatg
     6301 aaagacttaa aaactattat attttaaata aagccaaatt agaaaaagca tctaaagata
     6361 tgttagtaat gcatccatta ccaagagtaa atgaaataga catagacgta gatggtgatg
     6421 atagagctgt atattttaaa caagctaaat atggaatgta tgttagaatg gctttaataa
     6481 taaaactttt aggtataagt gaagactaat agttatcata taatagtaaa ataaaggaga
     6541 ttttgggatg tataaaattc tggaaaatat atatataggc gaagatatgt atagaatgaa
     6601 agtaaaaggg acttttgaag gtaaaatggg acaattctat atgctaaggg catgggacac
     6661 ttatccagta ctttcaagac ctataagtat acatgatata gatgaagaag ggataacttt
     6721 tctttataaa gtagtaggag aaggaactca aattttgagt aacctaaaag taaatgatac
     6781 tataaaatta gaaggccctt atggtaatgg atatgctaag gttgatggaa aggtagctct
     6841 agtaggagga ggaatcggtg tagctccact atatttggtt gctaaaaata taaaaaattg
     6901 tgacgcatat ctagggttta gagaagatgt tatattagaa gaggaatata agcaagtatg
     6961 taacgaagtc tatacaacag taggaaatac ttttgtaaca gatataattg atgtggagaa
     7021 atatgattat atattaacat gtggtccaac tccaatgatg gaaaaattag ttaagatggt
     7081 agaaggtact aaaacgagaa ttatggtatc tcttgaaaat catatggctt gtggagtagg
     7141 tgcttgttta gtgtgtacat gtaaaactaa tgaaggaaat aaaaagactt gtaaagatgg
     7201 tccagtgttc tggggagagg acgtgatttt taatgggtaa tttaagtgtg aaatttggaa
     7261 gtgtagaatt taaaaatcca gtaataatgg cgtctggaac ttttggattt ggaaaagaat
     7321 ataatgaaat ttatgatata caaaaacttg gtggtataag tagcaaaggt cttactttaa
     7381 ataaaaaacc tggtaacaat ggtatgagag ttcatgagac accgtctggt atgatgaata
     7441 gtgttggtct tgaaaaccct ggagttcaag gttttataga caatgaatta ccatttttca
     7501 gtaaactaga tttagtaaga atagctaatg ttggaggtgg gacattagaa gactacttat
     7561 taggggttca aatgttaaat gataaaccta tagacattat tgaattaaat atatcttgcc
     7621 caaatgtcaa agctggtgga atggcttttg gtataaaaaa tgaagtggca agagaagttg
     7681 ttcgtgaggt aagaaacata acgaaactgc ctttagtaat aaaattatca ccaaatgcag
     7741 aagacattgt agaaatggca aaagtttgtg aagaagaagg tgctgatgga gtttcgttag
     7801 ttaatacatt taaagcaatg gcaattgata taaaaaatag aagaccagta tttgaaaatg
     7861 tatatgctgg gttatctgga ccagctataa aacctatagc tttaagaatg gtacatgaag
     7921 tgtgtaaaaa tgtaaatata cctgtaatgg gaatgggcgg aataactaaa gcaacagatg
     7981 ctatagaatt tataatggca ggagccactt gtattcaagt tggaactgca aactttatga
     8041 atcctagaat cggtattgaa ataatagatg gaattaatga atttatggat agagaaggaa
     8101 taaaaagttt agacgaaata agaggaatta tataaggtag aataaatagt attttaaaga
     8161 taaaaaatat agattaaata aacaataatt ttataacatt aacatggagg aaaaataata
     8221 tgagtaaagt agatgtagta gatatattaa agaaaagtga tgcattgttg gagggacatt
     8281 ttttattatc ttcaggaaaa cacagtaata gatatgtaca atgtgcaaaa gtattaagat
     8341 tcccagaata tgctgctgag gtattaagta cagttgttga acaaataaaa gacttagata
     8401 tagacttagt agtagggcca gctatgggtg gagtaatagt ttcttatgaa ttgggaagac
     8461 aattaggaaa agaagctgta tttactgaga gaaaagacaa tacaatggag ttaagaagag
     8521 ggtttgaagt taaaaaagga gcaaagataa taattgctga agatgttgta actactggta
     8581 aatcaactat ggagacaaag agagtattag aagccttagg tggagaagtt gtaggtgttg
     8641 catgtatagc agatagaact aatcatgata taggtatgcc tatatatagt gctataaaac
     8701 ttgatattca agtttatgaa tctgatgagt gtcctttatg taaggaagga aaattaccag
     8761 ttgttaagcc tggaagtaga gagttcaagg aattaggaat gtaataaaaa cttaattatt
     8821 tatagtagta ttaaaaaaaa gtgaattttt cagaataaaa atttggaata taaaatataa
     8881 attaaaaata aagagcagtt agccttataa atgaaggtta gctgtttttt tgttaaaaat
     8941 atatttacaa aataagagat agtagcagta caatataagt ataaaataaa aaccattgta
     9001 tgcattaggg aggggtaagt atgaaaaatc aattaaataa aagtcagaaa aaggttgtat
     9061 tttttggagt aggagctgta ggagctactt ttgcagaaca atttttaaac tctaaatacg
     9121 attttaagat tctttgtaat aaggaaagaa aaaaacgata tttagaagat ggatttataa
     9181 taaatggaaa aaggtatgat tttgattatg taactagaga tgaatataaa caagaagctg
     9241 actttataat tataggttta aaatataata atttgaaaga aaatataaaa gaattagatg
     9301 gattagttgg aaaaaataca gtcataatgt ctctgctaaa tggagttgat agcgaagaga
     9361 taataggtga aagatttgga attgaaaaaa tggtatattc atatgttacc aatatagatg
     9421 caaagaaaat caataataat attatacaca ctactaatgg gataattgta tttggtaaca
     9481 aagataacag tgaagataga aaaactaata taataactga ggtttttgat gatgtaaata
     9541 tagaatatgt tttatcaaaa gatattcaac gagatatgtg gtggaagtac atggttaata
     9601 ttggtgtaaa tcaaacttca gctatacttg gtgcacctta tggagttttt cagagttctg
     9661 aacatttaag agaattagca aaatctgcaa tgagggaagt tgttgctata gcccaagcaa
     9721 aaggtatatc tcttacagaa gatgatgtgg aaaattcatt acatagaata ctagaacatt
     9781 caaaagaagg aagaacatca atgcttcaag atgtagaagc tcatagacct acagaagtag
     9841 atatgttttc taagaatatt tgcaaacttg ggaaaaaata tagcatacct actcctataa
     9901 atcagacctt tttttacatg ataaaagtaa ttgaaagtag attttaaggg tttttgtaag
     9961 aaactttgat aattattgat tttaaatttt attaatgtta tatactattt aagttactaa
    10021 atatttttaa ctcttcaatg aaaatagttg ctgcttttga taaagttata tcttttggaa
    10081 atatatatga gaaatgtctg ttgtagctgc ttccaagctc tatgacagac aactcattgt
    10141 ttaaaacagg taagcttgtc actagattag agactattgt aattcctaaa ttatttctaa
    10201 cagattcttt gacagcataa ttacttccaa aaaccatcat actccttgga ataatttctt
    10261 taacacttaa gaacatatct aaataatctc tagttccaga cccatcttct ctgactatcc
    10321 atttttggtc ttgaagttta tcaaaactaa aatcttttaa caaatgactt ttgtatggaa
    10381 gtgctagaac catcttatct tcaaaaaaat attcttgaat aaatgaaggg gaagagcaag
    10441 taccttcaat aagaccaatg tctaaaatat aatccttaac atgagaagat acgattgacg
    10501 tattttttat aaaaacttct acatctatgt caggatactt ttgagaaaat aacgctagaa
    10561 aatttggtag aatatactct ccaatagtta aacttgcgcc aatctttaag tgaccagtta
    10621 tagcatctga aacttggctt acatcatgat aagtaatatt taaaagattt aatatttctt
    10681 tagctctttt atacaatatt tgtccacttt ctgttataaa aatggttttt tgtttaatag
    10741 acctgtttat aagcacaact ttaaaataat tttctaaatt ttttatgtgt ttacttacac
    10801 ttggctgtga taggtttaag tattccccag ctttagtaaa atttttgtat tcaacaacag
    10861 ctacaaatgt ttttaattct tcaaacaatt ttttgtctcc tttacctaat taaattttac
    10921 attttttata tactttctac agataattat actatatata ataaccatta aaaacattaa
    10981 tcattacgat attatatatt tattttactt atggttatta caattatata ctattgctat
    11041 gaagaaaact atattaatta taaggtaggt atattatgtt aaagaaaaaa agcattttga
    11101 cattaaaaac tataagggaa atattaccag ggttgtttgt atcagtatta gtaggttata
    11161 ttagtatatt tatttctatt ttaattccta aggtaggagc agcatcaatt tctatatttt
    11221 taggtatgtt tgtaggaaac ctatttttaa atcaaaaagt gtttcaaaaa ggttataaat
    11281 tttcagagac agatttgtta tcatattcaa tagtactatt aggagcaaca ctcagtgtat
    11341 ctaccttaat agacttaaaa gtttcaggaa ttttatttat aatattgcaa atgacaataa
    11401 caataatagc tgcactttat ataggtaaaa aactaggatt tgaagaaaac tttagatttc
    11461 taatggcaag tggaaatgca gtatgtggtt cttctgctat aggagcaaca gttccagtgg
    11521 ttaatgcgac agataaagaa aagggaattg cagtaactat tgtaaatgtt actggtatat
    11581 tccttatgtt tttacttcca ataatatctc aatttttata tagccatgaa cttgtaaaaa
    11641 cgtcagcaat gataggtggg actttgcaat caattggtca ggttgtagca agtggagcaa
    11701 ttgttggaga aaatgtaaaa gatttggcta ctatttttaa gatattaaga gtaatatttc
    11761 tagttgttgt tgtattagta tttggacata tgaaaaatca gtctaataag gaaatccttg
    11821 aagaagaaaa ggatgagatc aaaaagaaaa aagtaactat accatggtat gtaattggat
    11881 tctttgtaac ttgtgcactt ttttcaatga acattatacc aaaagaagta tctgtgttgt
    11941 gcaaagaaat aagtaacaaa ctagaaataa tagctttagc agcaattggt ttaaaggtta
    12001 atgtaaaaga tttagtgaaa caaggaaaag aagtttcttt atatggttta tttataggta
    12061 tagtacaagt tgtatcagct gtagttttaa taaaaatatt tatatagcac aaaaatagta
    12121 tttgtaatat caatttcatt aattaaaata atatgatact aataatttat aatataaata
    12181 aaaaatgaat ttcgataagt ttaagtgggt ataaacttat cgaaattcat tttttattta
    12241 aggtaaaaat ttaaagtaaa atattatttt acataataat aaccttataa attttgaaat
    12301 tacttatctt tgtgttaaaa taagtaaaat gcacatatta aagctaagtt tttaagtaaa
    12361 taaacaaaat gaaaatataa atattaagga gatttagtat atgaatgttt atgaaaaagg
    12421 taatggagtt atactagaag gagtaacaga ttttgaccca gtacatatat ttgagtgtgg
    12481 tcaatgtttt agatggcaca aacaagaaga tggctcatac actggtgttg caaagggaag
    12541 aatattaaat gtcaaaaaag agaatgataa aatatattta aataatacga atttaaagga
    12601 gtttaatagt atctggtata attactttga tttaggaact gattatacag aaataaagaa
    12661 taagctaaaa aatatggatg aatatttaaa taaggctact gaatttggat ggggaataag
    12721 aatattaaga caagatggat gggaaatgct catatcattt ataatttcct ctaataatag
    12781 gattcctatg atacaaagag ctatagaaaa tttatcaaga aaatttggta agtatatagg
    12841 tgaatatgaa ggtaaagaat actatgcatt cccaacacca gaagagttaa ataaggcctc
    12901 acaagaggaa ataagagcat gtcaaacagg ttttagagat aagtacataa aaagtactac
    12961 acaggcagtt atagagaata atgataaggt atccgaatat acaaatttaa gtacagaaga
    13021 ttgtagaaaa gagcttttaa aatttaatgg agtaggccca aaagtatgtg actgtattgc
    13081 attatttggt atgcaaaaat atgattcttt tccagttgat gtttgggtta agagagttat
    13141 gcaagaattt tatatagatg aagacatgag tttacctaaa atgagaactt atggaatcga
    13201 taaatttaaa gaaatgtctg gatttgctca acagtactta ttttactatg caagagaact
    13261 cggtatagga aaataaatta agggggagaa attatgggag taataggaac aatatttctg
    13321 ttctatttaa ttatatcata tctggctgga gccataattt ctgtgattat attacttgaa
    13381 aatagagatc ctgcaaaaac aatgtcttgg ctattaatgt ttattatatt tccaggtata
    13441 ggtttaatga tatatgctat ttcaggtaga aatattagaa aaagaaaatt atttaaaact
    13501 caaaaactag ctaataatat aaaagaaaag aaactttttg atacattaga aaagataaca
    13561 gaaatagttg aattagaaaa agaatctata aaacaaaata agcttttaag agacgaagaa
    13621 gatggtagtt atagaaaaag ggtaataaat atgctattaa agactggtat gtttcccttt
    13681 actaaaaata ataaagtgga tgtgtttgta gatggaaatg aaaaatttaa aagacttata
    13741 gaagatataa gagaagctaa agaccatatt catttagagt attttatcat caaagatagt
    13801 gaaataggta gggtgttaaa agaggaactt ataaaaaaag ctaaagaagg tattaagata
    13861 agaattttat atgatgatgt aggatgctgg agattttggt ttaatagaaa gtttttccga
    13921 gaaatgaggg aagtaggtat agaaattgca gcatttttac ctacaaaatt tcctataata
    13981 ggaggaaaac taaactatag aaatcacaga aaaattgttg ttattgatgg aataattgga
    14041 tatacaggtg gaataaatat aggagatgaa tatttaggaa aaaatgataa gtttggatat
    14101 tggagagata ctcatattag gattaagggt atttctgtat acatgcttca aatgacattt
    14161 ctgattgatt ggtattatac gacaaaagaa gtattagtga ctaaaaatta ttttccaagt
    14221 gtagggaata ttggtgaaag tatgatacag gttgttgcca gtggtccaga tagtgactgg
    14281 gaagatattc attatgctta tttttctgca atatgtcaag ctagaaaaaa tgtttatata
    14341 gaaactccat atttcattcc agatgaaagt ctattaaaag ctataaaaag tgctgctctt
    14401 agtggagtag atgtgagaat aatatttcct aaaattgcag accacaagat agtaaacata
    14461 gcatcttatt cgtattttga agaaatatta agagcaggtg gtaaagttta tttatataat
    14521 aaaggattta tacactctaa agtcgtaata atagatgata aaattgcttc tgcaggtaca
    14581 gccaatatgg acttaagaag ttttatgctt aactttgaag taaatgcatt tatctatgat
    14641 gaagaagtta ttagagtaat gacagaggat ttctttgagg atttaagcca ctgtgaagaa
    14701 cttaatttgg aggtatttaa gaatagaaat atcatacaaa aaatcaaaga atctgtagca
    14761 agattatttt caccaatatt ataaaaaatt attaaaaaag gtattgaaaa ttatgtgtga
    14821 ttggtatatt ataataattg ttagcactct attagataga gtgataataa ataaaaagta
    14881 tatatataaa tctacatata aaagtagtat taatttaaaa ataactaaaa acataggcga
    14941 actagtctat acttaatatt ttaggaggcg taaataatga aaataagacc attagctgac
    15001 agagtagtaa ttaaaaaagt agaagcagaa gaaaaaactg caagtggaat agttttacca
    15061 ggagcagcta aagagcaacc tcaaatagct gaagttgtag aagttggacc aggtggaata
    15121 gttgaaggga aagaaataaa aatggaattg acagtaggag ataaggttat attccaaaaa
    15181 tattctggaa cagaagttaa gatagaagga caagaataca caatactaag acagagtgat
    15241 gtattagctg ttattgaata aatatagaat aaatttatta ggaggagttt aaaatggcta
    15301 aagaaattaa attttcagag gaaacaagaa gagctttaga agctggtgta aataaattag
    15361 cagatacagt aaaagtaaca ttaggaccta aaggaagaaa tgttatatta gataaaaaat
    15421 ttggttctcc acttataact aatgatggag taactatagc aaaagagata gagttagaag
    15481 atagatttga aaatatgggt gctcaattag ttaaagaagt agcaactaaa actaacgatg
    15541 tagctggaga tggtactaca actgctacag ttttagcaca agctataata agagaaggtt
    15601 taaagaatgt aacagcaggg gctaacccaa tacttttaag aaaaggaata caaaaggcag
    15661 taacagtagc agtagaagaa ttaaaaaatc aatcaagaat agtagaaaca caagaggcta
    15721 tatctcaagt tgcttctata tctgctggag atgaagaggt tggaaaatta atagcagaag
    15781 ctatggaaat agtaggtaaa gatggagtta taactgttga agagtctcaa actatgaata
    15841 ctgaattaga tgctgttgaa ggtatgcaat ttgatagagg atttgtttct gcatatatgg
    15901 ttacagatgt agataaaatg gaagcagttt taaatgatcc atatatatta attactgata
    15961 aaaaaatatc taacatacaa gagttattac cagttcttga gcaaatagtt caacaaggta
    16021 aaaagttatt aataatagct gaagatgtag aaggtgaagc gttatctaca ttagtagtaa
    16081 ataaattaag aggaacattt gatgtagtag cagttaaagc tccaggattt ggggatagaa
    16141 gaaaagaaat gcttcaagat atagcaatac ttacaggtgc tcaagtaata tcagaagaat
    16201 taggctatga tttaaaagaa gctgatttat ctatgttagg tagagcttca tctgttaagg
    16261 taactaagga aagtactaca atagtagatg gttctggaga taaaaaagct atagaagaga
    16321 gagtaactca aattaaacat caagtagagc aaactacttc agattttgat agagaaaaat
    16381 taatggaaag attagctaaa cttgctggag gagtagctgt aataaaagtt ggagctgcta
    16441 cagaagtaga gttaaaagaa agaaagttaa gaatagaaga tgctcttaat gcaactagag
    16501 cagctgtaga agaaggaata gtagctggtg gaggaactgc ttttgttagt gttataccag
    16561 caataggaac gctaattgag agtttagaag gagaagttaa actaggtgct caaatagtta
    16621 aaaaagcgtt agaagaacca ttaagacaaa tagctataaa tgctggtctt gaaggtgctg
    16681 taattgtaca aaatgttgtt aattctgaag ctgaaactgg atttgacgca ttaaatgaaa
    16741 aatatgtaaa tatgatagaa gctggtatag ttgacccaac taaagttagt agaagtgctt
    16801 tacaaaatgc tgcatcaata gcaagtactt tcttaactac tgaagcggct gttgctgacc
    16861 ttcctgaaaa agaagacgca ggaatgccag gaatgggtgg cggaatgcca ggtatgatgt
    16921 aatttaaaaa atttaaaata taaattttaa tataaagaac tatttcgact tagattttaa
    16981 actctaagtt gaaatagttc ttttgtatat atctagtttt tgtatattta taaattcaat
    17041 acacatattt agataatcag tatctaggtt gtgataatat cttagagtag tattgttatt
    17101 ttttaggtta tgattttaga tatatattaa ttaaggtata attgttgata gagactaaat
    17161 caaatttaaa aggatgcgat aatatggact taagaaagtt gcttgaagaa gttaaaaatg
    17221 aaaatattga tatagatttt gcgttagaaa aattaaaaga tttaccttat gaagaccttg
    17281 gatatgcaaa tatagaccat catagagaat taagaaatgg ttacccagaa gttatttatt
    17341 gtgaaggtaa gagtgatgag catattttag ggattattga taaaatgaat caaaaaagtt
    17401 ctaatatatt ggggacaagg tgtagaaaag aaacttttct aaaaattaaa gaaatctata
    17461 gtcatgctga gtacgaagat ttgtctaaaa ttcttaagat tcaaaatcat gatatagaga
    17521 atataggaaa aggtaaaatt gtgattgcta cagggggaac ttctgatata ccagtagcag
    17581 acgaagccta tcatacagct aagtttttag ggaatgatgt tgatagaata tatgatgttg
    17641 gagtggcagg tatacatagg cttttaaata aaagacataa aatagatagt gctagagtaa
    17701 tagtagctgt tgcaggtatg gaaggtgctc ttgcaagtgt aattggtgga ctagttgatg
    17761 ttccagtaat agctgttcca acatctgttg gatatggagc aaattttgga ggattagcag
    17821 ccttactagc tatgttaaat agctgtgcat ctggaatatc tgttgtaaat attgataatg
    17881 gatttggagc aggatattta gcagcaatga taaataaact ataaatacat tgatataaat
    17941 taaacaaaac tatataataa aatttaattt ctattatatt tttactatta aaattgagga
    18001 gacatatatg agtgaaaaaa tactttattt tgatataata agcggtatat caggggatat
    18061 gacccttgca agtttattaa atttaggtgt gcctaaggaa atttttttgg aggaaattca
    18121 taaactaaaa atgagcgatg aatttaatat aaacatcagc tctaaaactg aaaatggaat
    18181 agtaggtaca aaagtagaag taattacaaa agaaaaacat acacatagaa atttagtgga
    18241 tatatttgag gttatagatg aaagtaatct aaacgaaaat gtgaaatcta aagcaaaaaa
    18301 aatatttatg gcaattggag aagcagaagc aaaagttcat ggaactacaa tagacaagat
    18361 acattttcat gaggtagggg ctatagattc aattgtagat atagtaggag cttctatctt
    18421 agttgattta ctttgtgtag ataaagtttg tgctagtaca gtgtctgttg gctcaggatt
    18481 tgtaaaatgt gaacatggaa ttatacctat acctgcacct gcaactatgg aaattttaaa
    18541 aggtgtaccg attaaattaa ataatgtaaa tggagaatgt acaactccaa caggagctgc
    18601 aatcataaaa gtcttgtgtg atgagtttgt agacgagttt gaattttctc caagacaaat
    18661 tggatatggt ataggtcata agaagtttga ggtaccaaat atgctcagaa ctgtattagg
    18721 tgaaaaaaaa aagaagaatt aatttatgaa attagtgcaa acattgatga tatgtcttca
    18781 gaaatctatt cttatttgta tgaaaagata ttaggtgaaa aagcattaga tatttataca
    18841 gagagcattt atatgaagaa gaataggcca gcaacaaaag tatcaatttt atgcaatgaa
    18901 tcagatttag aaaaatttat taaaatatta cttttagaaa ctagtacttt tggagtgaga
    18961 tataatgcat ataatagaga aattctagag agaaaatttg tgaaattaga tacaaaatat
    19021 ggagtggtta cagtaaaatt agggtattat aaaggagaac tagtcaaggc gactccagaa
    19081 tataatgaat gtaaaactat agcaaaaaat gaagatattc ctataaaaaa agtgtttgct
    19141 gatataaatt ttagaataaa agaagaattt agtgaaaact tattgacata agtaataaat
    19201 tttgataaat taatattcag ccttattaaa taaaagtaaa aagaaaaaaa tatataaaat
    19261 ataaactcac tcgtatatgc tcagaaatat ggtctgagag tctctaccaa gataccgtaa
    19321 atatcttgac tatgagtgaa attattatac caaaagacct agttaagtaa atatgtaggc
    19381 tgagttgtac tccctatgtg ttggctataa gataaaggta ttttggaagc ctgtatagta
    19441 atttcacttt tgctagaaat tatggaagtt actatacagg ttttttgtgt aaaaagattt
    19501 aatataattt agactgtatt gtgttaaaat aaatatataa aaactatatt atacaaggag
    19561 agatgtgaat ttatgaaaca tgaattagta cttgtaatag attttggagg gcaatataat
    19621 cagttgatag ctagaagagt tagagaaaac aacgtatatt gtgaaatact tccatgtact
    19681 gcaagcatag aaagaataaa agaaaaaaat cctaaaggga taatatttac aggtggtcca
    19741 aatagcgctt atttagaaga ttctccaaca atatcaaaag aaatatttga actaggagta
    19801 ccaatacttg gaatatgcta tggtattcaa ataatgtctc atgtattggg tggagttgta
    19861 agaaaaggca ataaacaaga aaaagaatat ggaaaaacag ctataactta tggaaaatca
    19921 tcattatttg aaggaataac tacaaatagt gtatggatga gtcatacaga tttaatagaa
    19981 acagttccag aaggatttac tatagttgca aataccaatg attgtccagt agcagctatg
    20041 gaaaatgtag aacgaaacct atatggagtt caattccatc cagaggtaga acactgtttg
    20101 gaaggggaca agatacttac aaacttctta tataatattt gtaaagtaaa aggtgactgg
    20161 actacagatt cgtttataga agataaaata aaagaattaa aagaaaaaat aggcgataaa
    20221 aaagctttat gtgctttaag tggaggagtt gattcttctg ttgctgcagt tcttattcat
    20281 aaagcgattg gggacaactt aacttgtata tttgttgacc atggtttact tagaaaaaat
    20341 gaaggaaatg atgtagaaag aatatttaga gagaaatttg atataaattt aataagagtt
    20401 aatgcagaag atagattctt atctaaatta aaaggagttt ctgaaccaga agctaagaga
    20461 aaaataatag gtgaagaatt tataagagta tttgaagagg aatcaaataa attaggaaaa
    20521 atggatttct tagtacaagg aacaatctat ccagatgtta tagaaagtgg acatggaaat
    20581 gctgctacta taaagtctca tcataatgtt ggtggaatcc cagaagatgt agacttccaa
    20641 gaaattgtag aaccattaag agagttattt aaggatgaag ttagaaagat aggattagag
    20701 cttggtatag aagaaggatt aatatttaga catcctttcc caggaccagg tctagggata
    20761 agagttatag gtgatgtaac taaagaaaaa tgtgatatat taagagaagc tgatgctgtt
    20821 tatatggatg agcttagaaa agcaggttta tatagagaaa tatggcaagc ttttgcaaca
    20881 ttaccagatg ttaagactgt tggagttatg ggtgatgaaa gaacatatgc ttatctagtt
    20941 ggtttaagag cggttacttc ttctgatgga atgacttctg actggtataa gatgccttat
    21001 gatgtattag aaagaatttc taatagaata ataaatgaag ttgatggagt aaatagagta
    21061 gtttatgata taacttctaa accacctgga actattgaat gggaataaaa tatagaatga
    21121 taaaaatccg tatgaacaca ggatttgctc tatcttctta tcctatgcta tactagcttg
    21181 atattattca tatttgcaag tatcttgtag aataataagt aaaaagagca aaaatgctct
    21241 gctgaacaat aaattcagca gagtattttt ttattttatt ttgccgtgct cttgagctcc
    21301 aagcattaga catagatgat tttgttagat tttggtttta ttgtatcagc tctgaaaagt
    21361 gaattgatac aataaaaaga ggcatttatt gattattgat ggagatatat gttacgttac
    21421 ttttgttgga aatttgagag atagcgtggt ataatgggta aaataaattc atataacaaa
    21481 gagatggaga gtatacttat atttgatata ggaggtatat ctgtgaaaaa tactttttct
    21541 gaggttaaat tgtttcaagt taagccagac aggctagatg attttgaaaa attgatagtt
    21601 cttgtagctg aagaacaaaa acagcaaaca ggttgtattg acattaaata tttaaagagg
    21661 ttctatattt ttgacaatat aaaggaacag cctagggaac tgactaaaat tgttaaatgt
    21721 gtaaaatatt attcttactg ggagtttgat actttagaaa actattcaaa tgcaacacat
    21781 tggtttttcg atacatattc aaaggaagta ttcaagcttt taattatgcc ttttgacata
    21841 aactgtggaa attcaattta ttgaattgaa tagcaaatga gtagtatcac ctttggataa
    21901 tggaaagtca aggtattttc ttatggattt tgtggagtta agacactcga agttatgtac
    21961 aggattcttt ttttaaaaaa cctattttta ttggtttaaa tttgacaatg ctatttattg
    22021 ttatctatat attgattttg tttacaatat atttagtcaa gaaaaatgaa tttatagggt
    22081 atattttagc tcgaggaatg ttaaagttgt gttttattat aggtattatg ctttcaattc
    22141 aaacggtatt tcaacttgtg aataagattg aaataccagt tcctgcttta attactaaag
    22201 tgttaatttt tgttgttttg gcggtatttg ctagatatat tgaaagaaat ctaaaaggaa
    22261 atttcattta tagcaacagt gatttttaga tgtagtaatg aatgttgatg ttaaaaacaa
    22321 cctctgacta agtatccaac tgttttacta aaataacagt ttcatctatt ccataatctc
    22381 cagtcccata gagaggtatg tatttatcca ataaataatc actcattggt ttagtagatg
    22441 gcttaaatcc agctttttta tatgccttga cagcccttat attttttctt gatggtgcaa
    22501 taattagttc gcaaatatcc attgttttat ttaaaaaatc tccaagtgaa ataatggcat
    22561 ctactccaaa accttttcca caattagcct cacagttcat ccaaatgtca atttctgcaa
    22621 gagcttgttt taaatgaaaa caagaatagc taataaatcc aactggttct gtattactta
    22681 ctatgagaaa acctctgcca tcttttggtt tagcaccagt gaaaaaatac tcctcataat
    22741 cctcttcaca aaattcttca taagttgcaa taggtatatt tggataatta ggtagcccag
    22801 aatgagattt tgtagtttca gactgaaaac accattcgta tactttttgt ctatcatcta
    22861 atgtggcagg aattaaactt attttatcac catttatcat aatttttctc tccagtcttc
    22921 acatagttta atatttactt acagtataag cttaaattga taaattctaa cttacatata
    22981 ttgtaacata tccaaaatac ataatcactg aatattgtta tgtcgtaata gatttatgta
    23041 atacagtgtt agaaaatatc acatatcaaa aacatcagaa ttttactaga aatagtatat
    23101 tttatttata tttaatatta ttcataattt tttatattcc cctaattaaa aactctttgg
    23161 tatacttata aataaactta atgatagaat aaaaaagctt tataactatt agatgcatag
    23221 aaaagcattt tatgtctatg aaatgtatat ctataaaaca tatagatgac ttttatatat
    23281 taatgtatta atattgatat tatagaagaa ttgagttgtc aataatacta aatcaaatat
    23341 ctatagaata tggagggatt atgaaaaata aaataattat aggaattact ttttcacttg
    23401 tattactaat gtctggatgt gtttcaaaac aaacagcaga aataaacgta ttagcaacta
    23461 ctgatttaca tggagttata ccttatgagt taacttctta tgtaaaagaa gaaagaaaaa
    23521 aagataaaaa tctaacttta gtagatgcag gagatttttt tgattaaaaa atagctacat
    23581 acactcgtaa ctttagttat gagttagtag ctaaaatagt cagcatatag ggaaacttat
    23641 atgtagagat aggataacac ctatccaata ctacttgaat tgcta
//
LOCUS       DBGJFK010000054        23306 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.054, whole genome shotgun sequence.
ACCESSION   DBGJFK010000054 DBGJFK010000000
VERSION     DBGJFK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23306
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.054"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            455..796
                     /locus_tag="ACOIAP_002533"
     CDS             455..796
                     /locus_tag="ACOIAP_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGZ2639414.1"
                     /translation="MKEENFINIEYEDKRFSINSKEVLYIEKQEYEVKIYTENGNYEV
                     GENAPCIRKLMKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            947..1360
                     /locus_tag="ACOIAP_002534"
     CDS             947..1360
                     /locus_tag="ACOIAP_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HGZ2639415.1"
                     /translation="MLELKNNSGTSERKLKYPCIYKHFKGKYYATMGLSKAIDNVENI
                     CEIYSKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFGRPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1560..2201
                     /locus_tag="ACOIAP_002535"
     CDS             1560..2201
                     /locus_tag="ACOIAP_002535"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGZ2639416.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILADKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIIKMNDTSHIKNHVKINNSALE"
     gene            2225..3478
                     /locus_tag="ACOIAP_002536"
     CDS             2225..3478
                     /locus_tag="ACOIAP_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGZ2639417.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNRDIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEALNKDLLNHNVKIIYNKKVIDIITEEIAIKDDSNKNKSKYLIKGI
                     ILDNGDKILGDKIIISTGGVSYSKTGSDGLMYKILKNHGHTLNKLYPALVPLTIEEKW
                     IKNLQGISIKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSSDEISSIIREFPNKNVLNNLKQILPQNFLKEILSLLSLSDKKASDLSK
                     ADEIKIIEYIKNMKLTCTGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3524..4174
                     /gene="cmk"
                     /locus_tag="ACOIAP_002537"
     CDS             3524..4174
                     /gene="cmk"
                     /locus_tag="ACOIAP_002537"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGZ2639418.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGVDVNNEKEVIQIAENSDIDFKDNSIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVQVQRKIGMKSSVILDGRDIGSYVFPNADYKFFLVATPEERGNRRYKELCDKG
                     YNTTLKAVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVISKINL"
     gene            4225..4821
                     /locus_tag="ACOIAP_002538"
     CDS             4225..4821
                     /locus_tag="ACOIAP_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGZ2639419.1"
                     /translation="MNFYKFVINIFKGFTRIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAVENREIAAIAKKELFKVKPLGFILKKMHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLTNDDHERISQEILEVIKQNYFKYSK"
     gene            4834..5673
                     /locus_tag="ACOIAP_002539"
     CDS             4834..5673
                     /locus_tag="ACOIAP_002539"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HGZ2639420.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKSDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKNKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVNVCEELVPTFAIETKDELDVNMLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5926..7080
                     /locus_tag="ACOIAP_002540"
     CDS             5926..7080
                     /locus_tag="ACOIAP_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese transporter"
                     /protein_id="HGZ2639421.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDTSKNNSKENKEKHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIILIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMVITTIPAIIVGMIVYAFLG"
     gene            7379..9076
                     /gene="ade"
                     /locus_tag="ACOIAP_002541"
     CDS             7379..9076
                     /gene="ade"
                     /locus_tag="ACOIAP_002541"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HGZ2639422.1"
                     /translation="MGNLKKQCDVASGREKADIVLKNGTIINVFTEELIVGDVAIVGD
                     TIVGIGDYKGTVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMIPSSVPATSFETNGIGEFSAKDMESYINN
                     PRILGLGEVMCFNDVINSDNNILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVNGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPIRAIKVATYNSARAYGLKRIGAIGAGYKADIVVLNDLE
                     KMEVDSVYKDGNLVKEEMFSNYNYDIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKLYESLPCVEGYFIPSEEYSKLCVVERHRMTGNIAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDIIVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTLT
                     AKEVQETTDNMLEIARKMGVPKYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            9318..9776
                     /gene="bcp"
                     /locus_tag="ACOIAP_002542"
     CDS             9318..9776
                     /gene="bcp"
                     /locus_tag="ACOIAP_002542"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HGZ2639423.1"
                     /translation="MLSIGTRAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDVQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEK"
     gene            9792..10535
                     /gene="yaaA"
                     /locus_tag="ACOIAP_002543"
     CDS             9792..10535
                     /gene="yaaA"
                     /locus_tag="ACOIAP_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGZ2639424.1"
                     /translation="MIIMLSPAKNMKNIEVSDRDLSLPCFIDNTKEIVENINTFSVED
                     FKKKMKINEKLAILNKNRFESIKFDKLGSPAILTYDGIQYKNIEAENFTRQDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQAKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGIFKVESTQAKKARGMMTKYIIKNRIRD
                     IEELKKFNLEGYKYQENLSNNSEYIFVKE"
     gene            10633..13323
                     /locus_tag="ACOIAP_002544"
     CDS             10633..13323
                     /locus_tag="ACOIAP_002544"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HGZ2639425.1"
                     /translation="MKKRKEWSSKMENHKQMPWHSRATHEILESLDSSEEGLTDTEAE
                     KRLKENGLNELRKKPNRTTLQMLWSQITDAMVLILIGAAILSLIFGEFTEAFVILIIV
                     TVNAVIGIVQEKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAM
                     VPADLRLIETSSLKIQEASLTGESVPSEKDADTILPKEYVLGDRSNMAYTSSIVTYGR
                     GVGVVVATGMNTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGA
                     FYQRPLLPMFMIAISLAISIIPEGLPATATIVMALGVQRMSKRNALIRKLPAVETLGG
                     ATVICCDKTGTLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCN
                     DACINPDKTDEILGDPTEGALIFMAKKFGIDQEILEEEYPRVFEQPFDSDRKCMTTVH
                     NIDEKIIAYTKGAVDEILDLCTKILTSKGERNITELDKKNIHELCLNMSKDALRVLGF
                     AKREISSIPKEDSENIEYDLTFIGIVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHK
                     VTATTIAHELGIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSL
                     KRIGEVPAMTGDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTISYAIK
                     EGRRVYRNIQKVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALA
                     LGVDPPSRNIMKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQ
                     TMAFCVLAFSQMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSALLIAVILFVPVFRN
                     AFNLTILNSLEWLITIALAIMSVVQVEVGKIIKRKKLKNS"
     regulatory      13373..13475
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            13583..14848
                     /locus_tag="ACOIAP_002545"
     CDS             13583..14848
                     /locus_tag="ACOIAP_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HGZ2639426.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVASVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENAFKIAKFLEKHENVDWINYPGLEDNKYYENAKKYLSKG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            14878..15768
                     /locus_tag="ACOIAP_002546"
     CDS             14878..15768
                     /locus_tag="ACOIAP_002546"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGZ2639427.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKKLTYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKSKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKNSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINRGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            16062..16505
                     /locus_tag="ACOIAP_002547"
     CDS             16062..16505
                     /locus_tag="ACOIAP_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGZ2639428.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLTKFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQENISSSIFDNYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            16535..18352
                     /gene="ftsH"
                     /locus_tag="ACOIAP_002548"
     CDS             16535..18352
                     /gene="ftsH"
                     /locus_tag="ACOIAP_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGZ2639429.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLNILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALSEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKTCH
                     KNAIEILENNIDKLHELAKYLLEKETITGDEFMEILNLN"
     gene            18530..21232
                     /locus_tag="ACOIAP_002549"
     CDS             18530..21232
                     /locus_tag="ACOIAP_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639430.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYASGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKKFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     VSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETASKREENTKMIYQIIKGFLRLSNKDDIINKGIELLSLSLSRDVICYLNVDKYNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCVDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVEDNKDKGSTFKFSLPKENE"
     gene            21266..21964
                     /locus_tag="ACOIAP_002550"
     CDS             21266..21964
                     /locus_tag="ACOIAP_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639431.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEVQQKDDVKSTFEVDKLLIDFDKRKVIVDDIEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            22321..23277
                     /locus_tag="ACOIAP_002551"
     CDS             22321..23277
                     /locus_tag="ACOIAP_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HGZ2639432.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYSFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
BASE COUNT         9360 a         2472 c         4120 g         7354 t
ORIGIN      
        1 tcattttttg tactttatga ttatattctt aatctcgtaa aaatttctcc tgaaagaaga
       61 actgcttttt tagtaatagt tttactatta atattatcta acatttcaat ctttgtatta
      121 atacatataa tacttaagat taaaattagg aaaataagat aaatcttaat agggttcatt
      181 taaattaaaa gttaataatt acttttttat gtataatttt acataaattt gtgtaaaagt
      241 tattttatta aagatagata tacttatata tacagatatg attaaaaaaa atctttttaa
      301 ctttaaaaat taatgttaaa aaataaactt atacactaat attaacaata attatttaaa
      361 tatattaagt aaatcagtct tacatatatt tccgatagat tatattgata aaaaacacta
      421 aaattaaatt aataaagtac ttggagggat ggaaatgaaa gaggaaaatt ttattaatat
      481 tgaatacgag gataaacgtt tttcaattaa tagtaaagaa gttttgtaca tagaaaagca
      541 agaatatgaa gtaaagattt acacagaaaa tggtaattat gaagttggag aaaatgctcc
      601 ttgtataaga aaactaatga aagaagaaaa ttttttcaaa tgtagtaata gttatattgt
      661 aaatttagat aagtgtgaat tttatctcag caataattgt atttttgtga ataataattt
      721 tataagaatt ttaggttcag aaagaaaaaa gaagttaaaa aagaaattag aaaaattata
      781 tgattatgaa gattaatatt gagaggctgt attttataca gcctctttat ttattcattg
      841 tattattaat aaattttaaa ttatgataaa atataaaaca agtaacttat ttcagaaaaa
      901 aatacttttt aaaagaaagg gacgagatat gggagattat aataaaatgc ttgaattaaa
      961 gaataattca ggtactagtg aaagaaaatt aaaatatcct tgtatctata aacatttcaa
     1021 agggaaatat tatgctacaa tgggtcttag caaagctatt gataatgtag aaaacatatg
     1081 tgaaatatat agtaaagaaa atttaatcca aaatagaaat aaatataaat tagttattag
     1141 acatactgaa agagaagaag atatctatgt ctatagagat ttagatggaa acttttatca
     1201 taaaaaagaa gaagatacca atgatttagt tttatacaag actttatatg acgatacagg
     1261 aatatttgga agacctttgg atatgttttt agaaaaagta gatacagata agtatgtcaa
     1321 ttcaattcaa gagtacagat ttgaagaagt atataaataa tataagagaa atatgtttat
     1381 aaatttagaa aaattattta agagtataat aatttgcaga aatacaaatg agatttattg
     1441 taaacaatat gttagattgg attataaaat agaaacaaag taaagtatta tatgatataa
     1501 ttaagttttg agaagtgata ttatatttaa taaaaaatag gcatatatta ggaggacata
     1561 tgggaaatac tttttatata gtaagacatg gacaaacaga ttggaatata ttaggaaaaa
     1621 cacaagggca tggtaattct gaccttacac ctcaaggtat agaacaggca aaagaacttt
     1681 ctgaagatat tggcaagtat tcaattgatt atatttttag tagtgacctt ggaagagcaa
     1741 tgcaaacagc tcaaatttta gcagataagc tcaatattga agttcaaaaa actgaagcac
     1801 ttagagaaat gggattcgga gtttgggaag gtcttttaat aaaagaaatt caaaaggatt
     1861 attcagatat atatgcaaca tggagaaatg agccacattt agtaaatata ccagaaggcg
     1921 aaacgcttaa aattataaaa gaaagagtag atgcttttat aaaggaatta aatgaaaagt
     1981 acgataataa aaatataatt cttgttacac attcaattac attgagggtt atgttgttgt
     2041 catttttaga atcagggatg gaaaatatat atagaattaa gcaggataac actgctttaa
     2101 acatagtaga atttaaagat tacggacctg ttataataaa aatgaatgat acaagtcata
     2161 taaaaaatca tgtaaaaata aataattctg cattggagta ggaatcaatt ataaggagaa
     2221 atttatgagt aaagttatag tagttggtgg aggagcttct ggaatgatgg cagctttgtc
     2281 agcttcaaaa aataataatg aagtaatatt agttgagaga aatggagaat taggaagaaa
     2341 actgagagca actggtggag gtagatgcaa ttttaccaat aacagagata tagaagattt
     2401 ttttgataaa gtcgttagca ataaaaaatt tctctatagt agtttctata catttacaaa
     2461 taaagacctt atttcatatt ttgaaagtag aaatttggaa tataagattg aagaagaaaa
     2521 tgaccacaaa gtatatacta aaaatgataa atctatagag gtaatagaag cattaaataa
     2581 agatttactc aatcacaatg taaaaataat atataataaa aaagttatag atattataac
     2641 tgaagaaatt gctataaaag atgattctaa taagaacaag tcaaagtatc taataaaagg
     2701 gattatttta gataatggag acaagatact aggagacaag attattatat caactggagg
     2761 agtgagttat tcaaaaacgg gttcagatgg tttaatgtac aagattctta aaaatcatgg
     2821 acatacatta aataaactat atcctgcttt agttccactt acaatagagg aaaaatggat
     2881 taaaaatttg caaggaatat ccattaagaa tgtggaaata tcttgtaaga ttaagaaaag
     2941 gaaaatatca aaatcgggag acatgttatt tgcacatttt ggaataacag gaccttgtgt
     3001 gcttataatg tcttcttata ttaataagat tattgaaaaa gaaaaggtag aattaaatat
     3061 agatttttta ccaaatttaa gtagtgatga aatttctagt ataatcagag aatttccaaa
     3121 taaaaatgtt ctaaataatc ttaagcaaat actacctcaa aatttcttaa aagaaattct
     3181 atctctatta tctttgagtg ataaaaaggc aagtgatttg tctaaggcag atgaaattaa
     3241 aattattgag tatataaaga atatgaagct aacttgcact ggaactacag gtataaacac
     3301 tggtatggtt acttctggtg gtatttcagt taaagaaatt aattcttcta ctatggaatc
     3361 taaattagtt aagaacttat tttttacagg ggaagtaatt gatatagatg cagaaactgg
     3421 tggatacaat ttacaaatag cattttcaac tggatatctt gcgggtatta gtgtataaat
     3481 ataatttttt aataattaaa tatgaataaa tagaggtgta tatatgggta atttagttat
     3541 agctgtagat ggtccagcag gagctggaaa aagtacaata gccaagatag tagcaaaaaa
     3601 gctaaatata aattatatag atacaggtgc tatgtacaga gcagttactt ataagtgttt
     3661 aaaaagtggg gttgatgtca ataatgaaaa agaagttatt caaatagctg aaaattcgga
     3721 tatagatttc aaagataata gtatatattt ggacaaagaa gttataaatg aagaaataag
     3781 aacgatagaa gtaagtaata atgtttctaa tgtggcaaaa ataaaagaag taagacagtt
     3841 gatggttcaa gttcaacgaa aaataggaat gaaaagttca gtaatactag atggtagaga
     3901 tataggttca tatgttttcc caaatgcaga ttacaaattc tttttagtag ctactccaga
     3961 agaaagagga aatagacgct ataaagagct ttgtgataaa ggatataata ctactttaaa
     4021 agcagtaatt gaagatataa taagacgaga tgaaattgat tcaaatagag aatttgcacc
     4081 attagtaaaa gctaatgatg cactagaaat agatactaca ggaaaaacca tagaagaagt
     4141 tgtagaagaa gttatatcta aaataaatct ttagtttttt atgtattata ataaaaataa
     4201 atgtagtgtt gaagggagat aaacgtgaat ttttataaat ttgtaataaa tatttttaaa
     4261 ggttttacta gaatattttt taaatatgaa gttataggtg cagaaaatat tccagataga
     4321 gggaatatag taatagcatc aaaccataaa tcgaatctgg accctatatt cttagctgct
     4381 gccgtagaaa atagagaaat agctgcaatt gcaaagaaag aattgtttaa agtaaaacca
     4441 ttaggattta tattaaaaaa aatgcatgtt atgcctataa atagagaaaa gccagatgta
     4501 tctacaataa aaactatttt aaggtcagtt agagatggtt atgtgttagg catatttcca
     4561 gagggtacta gaataaaggg agattctttt ggtaaggcta aggcaggtct ttctgtattt
     4621 acaataaaaa gtaaatctaa agttgttcca gtatcaataa tatccaaata caaacttttt
     4681 agtaaagtaa ttgtatatat tggagaacca atatcatttg aagaacattt taaggaaaaa
     4741 ttgactaatg atgaccatga aaggatatca caggagattt tagaggtcat aaaacaaaat
     4801 tactttaaat attcaaaata agggggtaaa tttatgaaca taaaaatagc aaaaaatgct
     4861 ggattttgtt ttggagtaaa aagagcaatg aaaatggcat gggatgaagt tgaaaaaagt
     4921 gattctggca tatatgcttt aggtcctctt attcataaca agcaagcagt agcaaaatat
     4981 gaagaaaaag gtcttaagac tgtgaatgaa attgatacaa taccaaatca tgaaaatatg
     5041 ataataaggt ctcatggagt tcctgaaaat atatataaag aagctaagaa caaaaaatta
     5101 aaaattgtgg acactacatg tccatttgta aagaaaatac atacagtagt aagtgaatat
     5161 cataataaag gctatgagat aatagttatt ggagatatga aacatccaga agttataggt
     5221 ataaatggat ggtgtgaaaa ttcagctata ataataaaga ctttagaaca aatggaaaat
     5281 atggaatttg ataactcaaa aaaatattgc cttgttgcac agactacaat aaatccagag
     5341 ttgtatataa gtatagttaa taaactatca gataaattag aagaaatagt atttaatgat
     5401 acaatttgtt cagctacaaa aacaagacaa gagtcagcta aggagttagc taaagaagtt
     5461 gattgtatga tagttatagg aggcaaacac agctcaaata ctcagaagtt agtaaatgtt
     5521 tgtgaagagt tagtaccaac ttttgcaata gagactaagg atgaattgga tgtaaatatg
     5581 cttaaaaaat ataaaaattt aggtattaca gcaggagcat ctacacctaa ttggataata
     5641 gaagaagttg taacattcct tgaaaattta taaatttgat agataataaa aataggtgga
     5701 tattattata acataaaact tattataata tctgcctttg atttcatatt acatgtggca
     5761 aatagataac ctaatattaa aaagtgtgta tcttaagatg aaaaactaat agtataagat
     5821 gcgcactttt taatattaga aatttaaaat aaatattgat attgattatc aatagaaaat
     5881 ggaatataat ataattattg caaaattagt ctaggaggta aattaatgga aatgttaata
     5941 tccgcttctg aagaggcgtt tttacatgta ggttctatga ttggattttt tattttgtta
     6001 tttggatata ttaattataa aactagtgga aattttacta atattatatc aaaaaacaga
     6061 aaatttcaac ctttaatagg tgctttaatt ggagctatac caggttgtgg gggaagtttg
     6121 gcaataatgc cattgtatat aaatggaaaa ttaagctttg gagcaataat tgcaagttta
     6181 atagctagta tgggagacgc tgcatttgta cttatttcat caaatattaa aatgtatttt
     6241 tttgtcacta tagttagtac tattacagga ataataactg gacaattagt ggattacttt
     6301 aaactagaag aaaaattagg tctaaaaaac cgtagaaaat cggataaata cgatacaagt
     6361 aaaaataact ctaaagaaaa taaagaaaaa cataatcatg atgaaataat tttggatact
     6421 ctggctaaat ctcatggaaa tacaaataga cttgcattca taataacaca tggaaaggga
     6481 tataaaattt atataggaat tatattaatc ggttttatat ttatgtcact tgctcactct
     6541 ggacttaatc ttcctataat tgagaagtta cattcattgg aagaagtaat agcagtgatt
     6601 ggaatattat tttcaataat ttatatgtgg tgttttaaaa aggtatttaa aaattctaat
     6661 cagaaagagg aagaaaataa aaagatttct ttacgagaaa tgctgataca ttctgttggc
     6721 gaaatatcat ttgtaattac atggattttt attgcatacc ttatttacga tttgataata
     6781 ttaattttag gtggagatga atatttagtt aaactagtat tatcaacagg tgtaataagt
     6841 gtatttatag gtgcaggtct tgggcttatt ccaggttgtg gtatacagat tgtacttatg
     6901 tcattttatt tgaagggaac tataccactt ggggcagtga tagccaactc tatttctcaa
     6961 gatggagatg cacttttccc acttttagca atggataaaa aatcttcttt atgggctatg
     7021 gttattacta ctataccagc aataattgta ggaatgatag tttatgcatt tttaggttaa
     7081 atataaataa aaaagtatta aaaaattaat aaatcacata aatttatttg caagaatagt
     7141 aaacttaaat atataaataa aaaattcaat ataacttaaa ttattactta aatattaatg
     7201 agaacatggg agataatatt attccttatg ttctctctat ttaattaaat gaattatgga
     7261 acaaatttca agtgatactt tttattaaaa ctcatatata atatatatta ataaattaaa
     7321 ctataatatg taatacagcc agtatattga tataaaaaac ttaagaggag ttgtaaaaat
     7381 gggtaattta aaaaaacagt gtgatgttgc aagtggaaga gaaaaagctg acattgtact
     7441 taaaaatggg acaatcataa acgtatttac agaagagcta atagtaggag atgtagcaat
     7501 agtaggagat actattgttg gtattggcga ttacaaaggt actgtagaaa ttgattgtag
     7561 caacaaatat atatcacctg gttttattga tgcacatatg catattgaat ctacaatggt
     7621 aatgccaatt gaattatcaa aaaaattatt aaaatcaggt acgacaacca tcatagccga
     7681 cccacatgag ttggtaaatg taaaaggagc tagtgcaata gattttttat tagaatcgac
     7741 aaaagatata ccacttaatg tatatattat gataccttca tccgtacctg caacaagttt
     7801 tgaaactaat ggaattggtg aatttagtgc aaaagacatg gagagttaca taaataatcc
     7861 tagaatttta ggcttaggag aggtaatgtg ctttaatgat gttataaatt ctgataataa
     7921 tatcttggat aaactagagc tttttaaaaa taaagttgta gacggacatg cacctaatat
     7981 aaatggtaaa tcgcttcaga catatgtatg cgcaggaata gaaaatgacc atgaatgtat
     8041 aacttttgat gaagtatatg aaaaattgag agcaggttta aaaatattaa taagagaagg
     8101 aagtgcagca aaaaatttaa aatctatagt aaatggtatg ctaaagcata acttgccaat
     8161 tgaagagttt atgttttgca cagatgataa gcacttagat gatatagaaa aacaaggtca
     8221 cataagatgg aatataaaat gtgcgattga tttaggtatg gaacctatta gagctataaa
     8281 agttgcaact tataattctg caagagcata tgggctaaaa agaattggag caataggtgc
     8341 tggttataag gcagatattg ttgtattgaa tgatttagaa aaaatggaag tggatagtgt
     8401 atataaagat ggtaatttgg taaaggaaga gatgttttct aattacaatt atgacattaa
     8461 agataaagaa ttgcttaata cagtcaaatt taaatatatt aataaggaaa aaatacagtt
     8521 aaaagtaagt gaaaaaaatt atgtaatgga gattgtacct tatcaaattt tgacaaataa
     8581 gttatatgaa tcattaccat gtgtagaggg atactttatt ccaagtgaag agtattcaaa
     8641 actttgtgtt gttgagagac atagaatgac tggaaatata gcaattgctc cactaaaagg
     8701 atttggcata aaaaatggag caattgctac tactgtggct catgattctc ataatattat
     8761 agttgcaggg gataacgatg atgacattat agttgccata aattacttaa aggaaataca
     8821 gggtggttat gtaattgtat caaatggaaa agttcttgca cacctaagtc ttcaagtggc
     8881 tggattaatt agtactctta cagccaaaga agtacaagaa actactgata atatgttgga
     8941 gatagcaaga aaaatgggag ttccaaagta cgtagaccct tttattacac tttcttttat
     9001 ggcacttcca gttgttccac aaataagact tacagattta ggtctatttg atgttgagga
     9061 atttaaattt atataggcac cataataata aattaggata ttcaaaaata gagattgtac
     9121 tacaccccaa ttgttggact aaaaacctaa tgattggggt gtttatatat aactaaatac
     9181 aatgcatata aatacatgaa aattatatat ttatgaaact ttatacataa aaaataaaat
     9241 attttattta tatatagatt tatagggtaa taatataagc atagtataga attatcaata
     9301 aaaaaggaga gatatttatg ttgagtatag gaacaagagc accagaattt acactagaag
     9361 acaaagatgg aaataaggta agtatgtcag attttaaagg taaaaaagta gtagtatatt
     9421 tttatcctaa agataataca ccaggatgta cacgtcaagc ttgtgctttt agaaatgcgt
     9481 atgatggatt taaaaaggag gatgtacaag ttattggtat aagtaaagat agtataaaat
     9541 cacatcaaaa atttgcagaa aagcatgaac ttccttttat tttactttct gaccctgatt
     9601 tagtcgctat aaaagccttt gatgtatgga aagagaaaaa aatgtatgga aaaactgcat
     9661 tgggagttgt acgtgcgaca tatatcatag atgaaaatgg aattattgaa aaagtttttg
     9721 aaaaagcaaa accagacaca aatgcacaag agattcttga atatttggaa aaataggagc
     9781 aataagaatt tatgattata atgttatcac cagctaaaaa tatgaagaat atagaagtgt
     9841 ctgatagaga tttgagtttg ccctgtttta tagataatac aaaagaaata gtggaaaata
     9901 taaatacatt tagtgtagaa gattttaaaa agaaaatgaa aattaatgaa aaattagcta
     9961 tactaaataa aaatagattt gaaagtatta agttcgataa attaggaagt cctgcaatct
    10021 taacttatga tggaatacaa tataagaata tagaagcaga aaattttaca aggcaagatg
    10081 aagagtttgc aaatagttgt attcgaatca taagtggatt gtatggagtt gtaaaaccat
    10141 atgatagtat atatgaatat agattagaaa tgcaggcaaa attacgagta ggtgagttta
    10201 agaatttata cgaatattgg ggaaatcgta tatataaaga actaattaaa gaaaaaacag
    10261 ctattgtaaa tctttcatca aatgaataca gcaagtccat agaaaaattt attaaagata
    10321 gtgatacata tattacatgt acttttaaag taaataaaaa tggtatattt aaagtggaat
    10381 ctacacaagc aaagaaagct agaggtatga tgacaaagta cattataaaa aatcggataa
    10441 gagacattga agaactgaag aagtttaatt tagaagggta taagtatcaa gaaaacttat
    10501 ctaacaatag tgaatacata tttgtaaaag agtagaaatt ttattaaatg ttaaatgaca
    10561 ttgttaaatt taggtaaaat atacttagtg tgtattgaat tgaacttgat tttaaaatat
    10621 aattattctt aaatcaaaaa aagaaaggag tggtcttcca aaatggaaaa tcacaaacag
    10681 atgccttggc attcaagagc aactcatgaa attttagaaa gtctagattc atcagaggag
    10741 gggctcaccg ataccgaggc ggaaaaacgg cttaaagaga atggtttaaa tgaacttaga
    10801 aaaaaaccaa atagaacaac tttgcaaatg ctttggagtc aaattacaga tgctatggtt
    10861 ctgatactaa taggagcagc aatattgtcc ttgatatttg gagaatttac agaagctttt
    10921 gtaatactaa taattgtaac agtaaatgca gttattggaa ttgttcaaga gaaaaaggca
    10981 gaatcatcat tagaagcatt aaaaaatatg aactcaccaa cagctcgtgt tatgcgtgat
    11041 ggtgaagaaa atgttattcc agcaagtaat cttgtagtag gagatattgt ttttttagaa
    11101 gatggagcga tggttccagc agaccttcgt ttgatagaaa catctagttt aaaaattcaa
    11161 gaggcttctt taacaggaga atctgttcca tcagaaaaag atgcagatac aatcttacct
    11221 aaagaatatg tattaggaga ccgtagcaat atggcgtata catcttcaat tgtcacatat
    11281 ggtagaggtg taggtgttgt agtagcaact ggtatgaata cagaagtggg taacatagca
    11341 catcttttag attcacaaga tgattttgat actcctataa aacgtaaact taatactgtt
    11401 ggaaagacat taagtgtaat aggtattatt gtatgcgttg ttatatttgc aataggtgca
    11461 ttttatcaga gacctctctt gccaatgttt atgattgcaa tttcccttgc catatcaatt
    11521 attccagagg gattacctgc aacagctact attgtaatgg ctttaggcgt acaacgtatg
    11581 tctaaaagaa atgctttaat tagaaaatta cctgctgttg aaacattagg aggagctaca
    11641 gtaatatgtt gtgataaaac tggtacatta accttaaata aaatgactgt tacacatatt
    11701 gctgtcaatg gagattttga atctgggaaa gtaacatcaa tagatactgc atctgaaaaa
    11761 catccgttag tgtataaaga gattgtttat gctggtgcac tttgtaatga tgcatgcatt
    11821 aatccagata aaactgatga aatattaggt gacccaacag agggtgcatt aatttttatg
    11881 gccaaaaaat ttggaataga tcaggaaatt cttgaagaag aatatccacg tgtatttgaa
    11941 cagccttttg attctgatag aaaatgtatg acaactgttc ataatataga tgaaaagatt
    12001 attgcttata ctaaaggagc agtagacgaa attcttgacc tatgtactaa aatattgact
    12061 tcaaaaggtg aaagaaacat taccgaattg gataaaaaga atatacatga gttatgtctt
    12121 aacatgtcta aagatgcatt gcgtgtactt ggttttgcta agcgtgagat ttcatctata
    12181 ccgaaagaag atagtgaaaa catagaatat gatttgacat ttataggtat agttggtatg
    12241 attgacccac caagaactga ggtaattgat gcagtaagta cttgtaaaga agcgggtata
    12301 agaaccataa tgataacagg tgaccataaa gttactgcca caacaatagc tcatgagtta
    12361 ggaatatgga gtgaagaaaa tactgtgata tctggtgatg aacttgataa tttgagtgat
    12421 gatgaactag atgaagctgt taaaaatact acagtatttg ctcgtgtatc cccatttgat
    12481 aaacttagaa ttatacaatc tttaaaaaga attggagaag taccagcaat gactggggat
    12541 ggtgtaaacg attctcctgc cttaaagtct gctgatattg gtatagctat gggtataagt
    12601 ggtacagatg ttgcaaaaga ttcttctgac atgattttaa tggatgatag ctttacgaca
    12661 atttcttatg caataaaaga aggtagacgt gtatatagaa acatacaaaa agttatacag
    12721 ttcttgcttg ttggtaatat agcagagata cttacattgt ttgtagcaat attattaaat
    12781 tgggatactc cacttcttgc tgttcatatt ctgtgggtaa accttgcaac tgctactctt
    12841 ccagcccttg cgcttggagt tgatccacca agcagaaata taatgaagca tcagccagtg
    12901 aaatcaacca ctttatttga aaaaaatctt atacaaagag ttgttactca aggtatattt
    12961 gtggcaataa tgactatttt agcatataaa attggtctta atatagaaaa tcattctgta
    13021 ggtcaaacaa tggcattttg tgtattagca ttttcacaga tgttacgagc atttagtcag
    13081 cgttcaaata cagattcaat gtttaataga aacaatggta aaaatccatt tcttttaatt
    13141 tcatttttaa cttctgcatt gctaatagca gtgatactgt ttgtacctgt ttttagaaat
    13201 gcttttaact taacaatttt aaatagctta gaatggctta taacgattgc tttggctata
    13261 atgtctgtag ttcaagtaga ggttgggaaa attattaaaa gaaaaaaatt aaaaaatagt
    13321 tgacaaaatt aggaaaaata tataagatat aaaacataga aaaattaaat aaatcttatc
    13381 cagagaggtg gagggactgg ccctatgaaa cccggcaacc agtatattta tatacaatgg
    13441 tgctaaatcc tgcggcgaaa gctgagagat gagtataatt aagcttatac agagcctgag
    13501 ttatatactc aggctttatt tattttaact ctcatctgat aaatagttta attttttact
    13561 aaaatctaag ggggatacaa gaatgtataa taaagaaaca atatgtgtgc aaggaaatta
    13621 taaaccaggt aatggagaac caagagtatt acctttatat caaagtacaa cttttaaata
    13681 tagcagtata gaccaacttg ctgaattatt tgacttaaaa gttgatggac atatatattc
    13741 aagaataagc aatcctacta ttcaagcttt tgaagaaaaa ataagtttac tagagggagg
    13801 agtagcttct gtagctgtat catcaggtca atctgcaaat atgttagcag ttttaaatat
    13861 atgtaaatca ggagatagta tactttgttc ttcgaaagta tatggaggaa cattcaattt
    13921 attaggacct agtcttaaaa aatttggtat agatttaata tcatttgact tagattcaag
    13981 tgaagatgag atagtagaac ttgcaaagga aaatactaag gttgtgtttg cagaaacact
    14041 tgcaaatcca actcttgaag ttatagattt tgaaaaaata gcaaatgtag ctaaaagaat
    14101 taatgttcca tttattgttg ataattcatt agcatctcca gtgctttgta atcctttaaa
    14161 gtatggagca aatatagtta ctcattctac tacaaaatat ttagatgggc atgcttcaag
    14221 cgttggagga attatagtgg atggtggaaa ctttaactgg gataatggaa aatttccaga
    14281 attagttgaa ccagacccaa cgtatcatgg aataagctat actcaaaaat ttggaaatgc
    14341 tgcatatgca actaaagcaa gagttcagtt gcttagagac tatggaaatt gtttaagccc
    14401 attcaatgca tatcttacta atttaaatgt tgaaacacta catcttagaa tggagagaca
    14461 tagtgaaaat gcatttaaaa tagctaaatt tttagaaaaa catgaaaatg tagattggat
    14521 taattaccca ggacttgaag ataacaagta ttatgagaat gccaaaaagt atttatcaaa
    14581 aggatgtagc ggagtcttat catttggagt aagaggtgga ttagaaaatg ctaaaaaatt
    14641 tgtggaaaaa ctacagatag catctttggt tacacatgtt tcagatgtaa gaacttgtgt
    14701 tatacatcca gcttcaacta ctcatagaca attaacagaa gaacaattaa ttgcatctgg
    14761 agtattgcct tcgctaataa gattgtctgt tggaatagaa aatgtggaag atttaatagc
    14821 tgatttaaat caagctttaa atttttaata ttctaagaga aagagaagtg aaaagatatg
    14881 gctttaatac taccaaaggg attacctgtt attaataaat tattagatga aggaatagat
    14941 gtaatttaca aagaagattt taaaaagaaa ttaacatatg aagaaaacat agatactaag
    15001 atagccatac tgaatctaat gcctataaag atagatacgg aattagattt attaagaagg
    15061 atagataaaa caggattcaa tgtgtctgtg gaatttatta aaatttcaac aagagaaagt
    15121 aagagaagtt gtaatgaata tgtcaaagaa ttttataaaa catttgatga agccaaagga
    15181 gagtactttg atggttttat aataacagga gctccagttg agcaaatgga gtttgaagaa
    15241 gttgattatt ggaatgaatt agaagaaatt atggattatt ctaagagtaa aactaaatct
    15301 acattatata tatgttgggc agctcaagca agtctttaca aatactacaa tgtaaaaaaa
    15361 cttccattaa gtcaaaaatg ttttggagta tttaagcata aggtagataa aaatagtaaa
    15421 atagtagatg gatttgaaaa tgaatttttt gctccacatt caagacatac tactgtaaat
    15481 attgaagctc tgaaagagaa taaagagttg agcattgtga gtcattctaa agaagctggt
    15541 ccttatataa ttacaaattc aagagacgtg ttcgtaatgg gtcatagcga gtatgacaaa
    15601 tacacccttg acaaagagta taagagggat ataaacagag gagataaaat atcgatacct
    15661 caaaattact atatcaatga cgacccttca gaagagccaa ctgtaaaatg gaaaaaacat
    15721 tcggaactac tttttagaaa ttggataaaa aactatttga tacaataaat tttaatagta
    15781 aaatatcaac taaataaaat ataaaaataa taaggtataa agttaatttt aacgattctt
    15841 tataccttat tattttaaaa aaattgacct tataatagta gttttatata taagataata
    15901 aaattccaac tgaagttaca atattgtaat tgacaataga tacttaatat tataatattt
    15961 aatacattaa acattatagt attaagtatt tatttacaag atacacttaa gcctaaagtt
    16021 aatagttagt gaaataaagt atttttgtaa ggagcgtttg tatggatgag atgagtttta
    16081 agaaagagct actagagttg actagagata taaatatgaa atttacaact ttattaacta
    16141 aattttatca gccacttggt attacagcag ttcaagcttt gattttgtct gagttgtgtg
    16201 aacatggaga gaaaaaaata agcgatttag ggaaaaactt aaacatgaca aatagtaatg
    16261 tatcagtaat ctgtcaaagg cttgaaaaaa atggtttttt aaatcgtata agagatatag
    16321 aagaccaacg aattgtaaaa gtaaaagtta ccaataaatc attggatata caagagaata
    16381 tttcaagtag tatttttgat aattattttg aaaatatgac tagtgaaaaa ttgcaagaca
    16441 tggaagatat aatagaaggt ttagagaaat taaataaact tttaacctac attgattgca
    16501 aataacataa aataatttaa aggagaataa aattatggat gaacataaac cccaaaaaag
    16561 gtctgcactc tattattata cagttataat aatagtagta atgtttttaa atgctttaat
    16621 atttccaagt ttaatggata agaaaatggt tgagattgac tatgggaagt ttcttacaat
    16681 gttggacaca ggaaaggtta aatctgttga gatagaaaac aatagaatag caataaatcc
    16741 atctagtagt aaggataaga atatatatat aactggtaga atggatgacc cagaattggt
    16801 agatagacta aaaaatgcaa aagtagaatt tactaaggtt attcctaagg aaaattcacc
    16861 tcttttaaac attttactta catggataat acctataggt attcttatgc tatttggtaa
    16921 tttaatgatg aagtctatgc aaaagcgaat gggtggtaat gctatgcaat ttggaaaaag
    16981 caatgccaaa atgtatgtat ctgctcaaag tggaaaaaga tttaatgatg tagctggtca
    17041 agatgaggca aaagaagctt taagtgaaat agtagatttc ttacacaatc cagaaaagta
    17101 taaaaaaata ggagcacaaa tgcctaaagg tgcactttta gtaggacctc caggtacagg
    17161 aaaaacacta cttgcaaaag ccgtagcagg tgaagcaaat gtaccatttt tctcaatatc
    17221 tggttctgag tttgttgaga tgtttgtagg aatgggagct tctaggattc gtgatttatt
    17281 taaacaagca aaagaaaaag ctccatgtat agtgtttata gatgagattg atactattgg
    17341 taaaaagcgt gataatggaa gtggactagg tggaaatgat gaacgtgaac aaactttaaa
    17401 tcagttgcta agtgagatgg atggttttga tggtggaatt ggagtagtaa tacttgctgc
    17461 tacaaataga cctgacagtc ttgacaaagc attacttcgt ccaggaagat ttgatagacg
    17521 tataccagtt gaacttccag accttggagg acgtgaagct atattaaagg tacatgctca
    17581 aaatgtaaat gtaagttcag atatagatta taatgcaatt gcaaggtcta catcaggagc
    17641 atcaggtgca gaacttgcaa atattgtaaa tgaagcagca cttttagcag ttaagtctgg
    17701 tagagatata gtagagcaac aggattttga tgaatctgtt gagactgtaa ttgctgggta
    17761 tcaacgtaaa ggagctgtaa tttcagacaa ggaaaagaaa attatagcgt atcatgaaat
    17821 aggtcatgca cttgttgctg ctatgcaaaa acattctgca cctgttcata agattactat
    17881 aatacctaga acttcaggag cattgggata tactatgcaa gttgctgaag atgagagcgt
    17941 ccttatgtct aaagaagaag caattgacaa aataactact tttacaggtg gtcgtgctgc
    18001 ggaagaggtt atttttaaca cttgtacatc aggagcatca aatgatatag aacaagccac
    18061 taaaattgca agagctatgg tcactcgtct tggtatgagt gaagaatttg atatggttgc
    18121 tcttgaaact gtaagcaatc aatatttagg aggagatact tcccttgctt gttcttccga
    18181 cactgctgct aaaatagatg aagaagtatt taaaatagta aaaacttgtc ataaaaatgc
    18241 aattgaaatc ttagaaaata atattgataa gttgcatgaa cttgctaagt atttattaga
    18301 aaaagaaact ataacaggtg atgaatttat ggaaatactt aacttaaact aaaatgatta
    18361 tacacaaagt aaaaatgcct attgttaggc atttttattt tgtaattaag ttttttaaat
    18421 tcatatttaa atctttacat aatcttaatc actaaaaata catcttaact acaattttat
    18481 attggaattg atattataat agtaatgaat gatgtaagga ggttttttaa tggatagacc
    18541 gaatcctgat attctattag aaaaaataaa aaatgaagaa gaaaaactaa gtagaggtca
    18601 attaaaaata ttctttggtt atgcatcagg agtaggaaaa acctattcta tgttggaatc
    18661 tgcacaaaat ttaaagaaag taggtgttga tgtagtagtt ggatatattg aaccacacac
    18721 tagaccagaa accttggctt tacttgatgg attggaaatt ctccctgtaa aggagataga
    18781 atataaatct ataaaattaa aagaatttga cttagatgct gctttagcaa gaaaaccaga
    18841 agttatatta gtagatgaat ttgcccattc taatgttgct gggttaaggc atacaaaaag
    18901 atggcaagat atagaggaat tgctgttagc aggcataaat gtctacacta ctgtaaatgt
    18961 acaacatcta gaaagtctaa atgacattgt tgagataatt acaaacgtat cagttaaaga
    19021 gactatacca gataagtttt tggatacaaa tacacagtta gaacttatag atgttgaacc
    19081 tgatgtactt cttgaaaggt tcaatgaagg taagatatat aagaaagaac aagctactag
    19141 agcaaaaaat aattttttta taaaagataa cctagttgca cttagggaaa ttgcacttag
    19201 aaaaacagca gaaagagtca ataaagaagt tcaaatgacc agactatcaa agggtgatgt
    19261 aactgtaata cctacatcag atacgcttct tgcatgtata agtccatctc catcttcagc
    19321 aaaagttatt agaactgcat ccagaatatc agacagtaca tttgcaaaat ggatagcttt
    19381 atatgttgag actccaaaca cagcaagact tccatttgac gaacaaaaac aactacaaaa
    19441 taatctaaaa ctagctaaga agctaggtgg agaaataatt gttttacatg gtgaaaatat
    19501 aatagagcaa atacttagaa ttgcaaaact gagaaatgta acaaaaattg taataggtag
    19561 aaatcattca agtaataaaa ggtttagtaa aaagtttaaa aaagatatag ttgacaaatt
    19621 aattgatgaa gttgattata tagatataca tataattcca tataaatttg cctcagatgt
    19681 taaatacaaa cctaaaaagg ataaagtgtc aataaaatct aaatttaaaa ttagtaaagt
    19741 tgattttata aaacttatat ttattacttt gatgataagt attttagcat atgcagtaca
    19801 aagtatgggc tttataagag aaaatatatt gttaatatat atgttgggtg tggttttagt
    19861 ttctatgtgg actaaaggtt atagtacagg tataataagt tctgtattta atatagttct
    19921 gttaaattat ttttttacag caccattata tacattatct atagcagatt caaactatat
    19981 agtaacacta gttgtatttt caatagtagg tataataact agtactctta catctaagat
    20041 acaacatgaa gcagaaactg cttctaaaag agaagaaaat acaaaaatga tatatcaaat
    20101 aattaaggga tttttaagat tatcaaataa agacgatata ataaacaaag gtatagaact
    20161 tttgtctctt agcttaagta gagatgtgat ttgttattta aatgtagata agtataacaa
    20221 atcgaagctt tataaaaaaa atactaataa taaggataaa aatgatttgg atagtgaaga
    20281 tgaaaaagct gttgcaagtt gggttttatc caattcaaca gtagcaggaa atgatacgga
    20341 tacacttcct ggttcaaagg gatactatat accaattgta gggatgaatt taactttagg
    20401 agtagtagga atatcatgtg ttgattcaaa attggataca gaagatataa gcttaattga
    20461 aacaataatt gctcaaatgg caatagcact tgatagagaa atcttgtcag aagctaaaga
    20521 aaataccaat ctcgagattg aaagggaaag gctaagaagt aatcttttaa gagcagtttc
    20581 gcatgacctt agaactccac tagcaggaat atctggcgca gtaagtacaa ttataaaaaa
    20641 caagggtact ataggtcaag atataataga tgaattgctt agtggtgtat atgaagatac
    20701 tcaatggtta ataagacttg ttgaaaattt acttagtatg accaagatag atgaaggaaa
    20761 attggaagtt aaaaaacatt ctgaactagt tgaggaaatt atatcagaag cattacaaaa
    20821 aataaaaaaa agaattgaaa atgcacttat agatatcaat ataccagaac agatattatt
    20881 tgttcccatg gatgcaaaat taatagaaca agttttaatt aatttaatag acaactcttt
    20941 gaaatattca aaggaagatt gtaagataga gataaatgta tatgagaaag atgattatgt
    21001 ttggtttgaa gtatctgata atggtcctgg tatatcaaag gaacttaaaa agcatatctt
    21061 tgacagattt tttactggag aagaaggagc taaagattcc agaaagggtg ttggacttgg
    21121 attatcaatt tgtaagtcta taattcaagc tcataaaggt gaaattatgg tagaagacaa
    21181 taaagataag ggctcaactt ttaagtttag tttgcctaag gaaaatgaat agttttaaat
    21241 tttaaaatta gttttggagg aagaaatgag taaaaaactt atattgttag tagaggatga
    21301 taagacaata agaaaattta tatctactgc acttttaaca caggattatg atgtcaagga
    21361 ggctataact ggaaaagaag gtatatctat tgctgtttca tattctccag atgttgttct
    21421 cttagattta ggcttagaag atatggatgg aatagaggta ataaaagcta tcagacaatt
    21481 ttcaaatata ccaataattg tagtttcagc tagagagcaa gatagagata aggtagaagt
    21541 atttgatgca ggggcagatg attacttaac aaaaccattc tctatagtag agttattagc
    21601 aagagtaaga gtcgcattta gacattcaca agtagaagtt caacaaaaag atgatgttaa
    21661 atctacgttt gaagtagata aattattgat tgattttgat aaaagaaaag ttattgttga
    21721 tgatattgaa gtccatttga cacctattga atataatatt ctttcattac ttgcaaagca
    21781 tcatggaaaa gtgcttactc ataactttat aataaaagag atatggggta gtgttatagg
    21841 gaatgagact aagtctttaa gggtctttat ggcaacatta agacgaaaaa tagaaaaaca
    21901 acctgcaaac ccaagatata taatcacaga agttggtgta ggatacagat taaatgatga
    21961 atagttgtaa tatatattaa ttattagact atgtttttat taatatatta aaattatata
    22021 gtttagttaa aataagaatg aagtgtatgt gctgttgtca gtttagcaca tgcattttat
    22081 tttttaaatt tttttagtat caataatttt ttagtattaa taatatgaaa tatgttttaa
    22141 aataagtata tggtataatc tgtaataaaa gctttggtta aataataaat gtacttaaca
    22201 cttgtcttat aataaattta atatttatat taaataataa ttattaaaat agtgtaaaat
    22261 aattacagta aggattataa aaaattttta gaatgtaaat tgaaatttag gagtagatgt
    22321 atgtatatac tgaatttaaa tacaagagag actattgaag attttagaga taaattttat
    22381 gtagcagaaa attcttatct tatattaagt gctccaaaaa atttaaaatt gcttaaagaa
    22441 acattggata tagatgaaat aacttttaat gattgtctta aatttgatga aataaccaaa
    22501 cttgatttat ttgataatta cgatttttta agcctaaata catttgaatt aagagatggt
    22561 gaagctgtta tagaagaggt aaatatgtat ttgtctgata attttatatt ggttgtagtt
    22621 aatgaagaac actttttatt tgaatttgta aaaaatatta ttttgaagaa ctctcaactt
    22681 gaaaaaaatc cagttattaa cctatttaag ataaactact tgattctcag agaagttata
    22741 aaaaatggtt ttgagtcttt ggaaaaagtt gaagagttga ttcttcaaat agaagatgaa
    22801 atgatggaca acattaacaa gaatcatgta tctagaataa gtgatgtaag aggattaaca
    22861 aggattatag ttaagaatac tagacctctt ttgtatattg gggatagaat agttaaagaa
    22921 aatataagat atttaaaata ttcaaatgta aaaaaatata atttagaaaa ttttcaaggt
    22981 atagattttg gaattgataa actatacagt ttcgcattgt caacacgaga gttagcagat
    23041 aaattattag atatttattc ttctagagta ggtgaaaaaa caaataattt aattacaaaa
    23101 ttaaccttat taacagccat atcagcacca cttacaatta taactggtat atatggaatg
    23161 aactttagat atatgccaga attaaactgg atttatggat atccagcaac tttatttttt
    23221 atgttatgta taatttttgt tggaattata atatttaaaa taaaaaaatt attgtaaatt
    23281 acagatgatt tttaattaat tttata
//
LOCUS       DBGJFK010000055        23162 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.055, whole genome shotgun sequence.
ACCESSION   DBGJFK010000055 DBGJFK010000000
VERSION     DBGJFK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23162
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.055"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..775
                     /locus_tag="ACOIAP_002552"
     CDS             <1..775
                     /locus_tag="ACOIAP_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2639433.1"
                     /translation="RIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAAT
                     KYSKQQFAIVDYTYKVQPANVISVSFQDNATGYLAGLIAGKMTDTGKVGFIGGVEGSS
                     RDKYESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDS
                     KRAIQVARENGGKVIAINKDQYDMAPNNVISSIIKDVEQPVYELIKNVVKDGFKGNKV
                     MEFKIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            930..1691
                     /locus_tag="ACOIAP_002553"
     CDS             930..1691
                     /locus_tag="ACOIAP_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6873 family GME fold protein"
                     /protein_id="HGZ2639434.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTVEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            1694..2512
                     /locus_tag="ACOIAP_002554"
     CDS             1694..2512
                     /locus_tag="ACOIAP_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HGZ2639435.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            2691..3293
                     /locus_tag="ACOIAP_002555"
     CDS             2691..3293
                     /locus_tag="ACOIAP_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HGZ2639436.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRVEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPGGIKNMIQDYLGEIIESEVKKSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIVQGLVTMFI"
     misc_binding    3783..4022
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4086..6005
                     /gene="thrS"
                     /locus_tag="ACOIAP_002556"
     CDS             4086..6005
                     /gene="thrS"
                     /locus_tag="ACOIAP_002556"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGZ2639437.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSNEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            6730..7821
                     /locus_tag="ACOIAP_002557"
     CDS             6730..7821
                     /locus_tag="ACOIAP_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HGZ2639438.1"
                     /translation="MIEKVGEKSKIIKTSKEYKRTIIEEKDREWTQKLNDILSRNNFS
                     NDELDKIKELIPKEILTSENVGEVVTEDGYARPEYDEVFKSLFTLNNEYGLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRLETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPEIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLIINPSSLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNAFDLSEDEIKEVYENN"
     gene            complement(8169..8366)
                     /locus_tag="ACOIAP_002558"
     CDS             complement(8169..8366)
                     /locus_tag="ACOIAP_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2639439.1"
                     /translation="MTIASDVIRCDTKTSILKHLLKKDSYSYEINKSILEKTKGLYEL
                     KEAILYTAFRRLEQSGAITSY"
     gene            8726..10066
                     /locus_tag="ACOIAP_002559"
     CDS             8726..10066
                     /locus_tag="ACOIAP_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGZ2639440.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKKISNKKINFCI
                     VGIIVFANIIYFFDAPLNIRVIISMIVTIAFYKISYDVRFIKSVLISLIYWMLLIAID
                     ALSISLTVWLNSINDMSNMGTGDIYRIESIILGKILLISALFLYRALKIKFNIEINKR
                     TLFYIVIPIVANIASFFVIFKYIFNLKFGNLIHNFQFVVISVVLLVSSITLILIAKKL
                     QQYNTLVVENNMIKNTLKCENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDRNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDIMQNFYLIKVENTKTNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKVVNNII"
     gene            complement(10408..10977)
                     /locus_tag="ACOIAP_002560"
     CDS             complement(10408..10977)
                     /locus_tag="ACOIAP_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGZ2639441.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
     gene            complement(11138..12388)
                     /locus_tag="ACOIAP_002561"
     CDS             complement(11138..12388)
                     /locus_tag="ACOIAP_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2639442.1"
                     /translation="MVKSLNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIIFSPIGGAIADIFNRRNLMVIFDFSSSITVLVLALFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQTSNIIKTIFIDINDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKYLKITNLYISFTICALMFIPMAFSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYAITIIQLKTPNELLGKVMSILFAGTTIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLIIAFISKITLRNEKL"
     gene            complement(12397..12630)
                     /locus_tag="ACOIAP_002562"
     CDS             complement(12397..12630)
                     /locus_tag="ACOIAP_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639443.1"
                     /translation="MIELIQRLNDVIYKINDKLNIHTKLVDPSSELMPLYSMLSIIVS
                     IFLIILGIKVRKKVLIVIAIIAIIVNVLIILDR"
     gene            complement(12681..13259)
                     /locus_tag="ACOIAP_002563"
     CDS             complement(12681..13259)
                     /locus_tag="ACOIAP_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2639444.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGTFYTFFDSKEKLFFEVLNGIQNRLISSVDEILGNMPQKEGFAKALKMLYRLYDKN
                     PFLYSPNNTDYITLLNKIPKEMLSQLEYNNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            13560..15020
                     /locus_tag="ACOIAP_002564"
     CDS             13560..15020
                     /locus_tag="ACOIAP_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGZ2639445.1"
                     /translation="MFNELRTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEAIKNTKESIKVWADMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     MKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVEKIKPLVENLTIGNPKDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLIVGNIRKNNLFYPTLLDNVNTDMKIAWEEPFGPVL
                     PIIRVKDISQAIEIANQSEYGLQSSVFTSDIDRAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVRGL"
     gene            15389..15994
                     /locus_tag="ACOIAP_002565"
     CDS             15389..15994
                     /locus_tag="ACOIAP_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2639446.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDDELSPQQCLRKIMLNHLRFP
                     KQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRLSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            15997..18564
                     /locus_tag="ACOIAP_002566"
     CDS             15997..18564
                     /locus_tag="ACOIAP_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HGZ2639447.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGVLFHNGEMPQEVSDAIKTAY
                     DGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDEVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYTLTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     FLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIALQSEKE
                     LWGLSEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAYSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEALIEQLDKNKSLSDMNGLIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     ALQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(18824..20908)
                     /locus_tag="ACOIAP_002567"
     CDS             complement(18824..20908)
                     /locus_tag="ACOIAP_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2639448.1"
                     /translation="MSKYIDFANIEYSLLMNALDVSVSKHLLDEHFTVVWANDRYYEM
                     FGYTKEEYETLFHNQCDLFYKDNPEDWNELVEYVEKTFSTGAKKYDYVCRMKHRNGKK
                     LWIKLFGFLTGEVVDGYPISYSVMIDITEQMMIKIEQTVTYNNFPGLIAKFKVTDFGF
                     QLLDANKKYFDMFKDNVNFLLDDINLESYLSAVYKYQSDFKAGKYVCFSVSPQNINGD
                     IVHMQVVAECIDWEDGKPIYLLIYSDVTTLVKQNEIIEKNNKELEKLAFIDSVTGGMN
                     HTKFNIIAKEVISQSPSGTYTLIWLNMQKFKLINDLAGNIAGDKLLKYIYNCISKHLH
                     EGELVTRIFADKFILLLKDKPEDITSRLNSMVTHINRFNDNADYKYILYFTAGAYVIY
                     DTSLDITNIQDSANVASKSIKNVENHGLCICNFYSKKDKEKLILEQSIENRMYEALEK
                     REFQVYLQPKLELSTQTICGAEALVRWIHPVEGIIPPNEFIPLFETNGFIIQLDLYVF
                     EEVCKTLKKWIDDGLNPINISVNMSRYHFSSNNFIKTYDKIAKKYDIPSHLIEIEITE
                     TIVFEDVKVFSEIINEIHKNGFKCSIDDFGSGYSSINMLKDIYVDTLKLDRAFFQSEH
                     LDSQRERDIIVSIIELAKKLKMTTVAEGIETSFQKDFLQEINCDMLQGYVFSRPLPIK
                     DFEKLMFQNSSN"
     gene            complement(20956..21855)
                     /locus_tag="ACOIAP_002568"
     CDS             complement(20956..21855)
                     /locus_tag="ACOIAP_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020397798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HGZ2639449.1"
                     /translation="MSITLDMPAYLFDSNYITNIYRVYSISSSFIVTGLYFCYKNHKN
                     NQINFDTVLEDKKNLNFLLSLMFVMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLV
                     GNYIAEKYSFRITQIKSYDIKNQLEYLESIKTEHEINKLNDIVYTDLLTGFYNRPFVN
                     QKLSEWMSNHYKFTLCFTDLNRLKLVNDNFGHQFGDKYISTTAKIIKKLINVENSLLF
                     RYGGDEFLFLLQDTSCIEAEKIMIDINYELSKLSNTDEYPYALSISYGLVEWDGISDI
                     ETLIAEADSLMYENKLKNKSTLN"
     gene            complement(22187..>23162)
                     /locus_tag="ACOIAP_002569"
     CDS             complement(22187..>23162)
                     /locus_tag="ACOIAP_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HGZ2639450.1"
                     /translation="VSHKLLLISIKNSDNKHFIPNIAVINFCILHLITISIMSIVENT
                     SPDIIFVNMSSRIISILIASILDFILWYSMDKIKEHIYVITQNQIEFSLFLKFIYFTL
                     GYILFDSIQIAFSPPSALTSYFILGSNILLSLQMIIFINHIYSIEKNIYLEKEHNRLK
                     MIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNSLLFSLIYIDLDKLKTI
                     NDKYGHLAGDNYIINFSSIIISNLKADDIFARIGGDEFIVIMPKSNENTTKEFIEKIR
                     KSMYNKISFSYGIVEVPSENKMTVEEIINIADIRMYTNKQNNHKRNSN"
BASE COUNT         8644 a         2834 c         3778 g         7906 t
ORIGIN      
        1 taggataaaa cttgaaaagc caaagacttc taaaagtttt aaagagagta tagaaaaact
       61 acataagtat gagccagatt tgataatagc agttggagct agatttgcag agccaattaa
      121 agaagctgct actaaatatt ccaaacagca atttgcaata gttgactata cttataaagt
      181 tcagccagct aatgtaattt ctgtatcatt tcaagataat gctactggat atttagcagg
      241 acttattgca ggtaaaatga ctgatactgg taaagtaggt tttataggag gggttgaggg
      301 ttctagtaga gataagtatg aatctggatt tagaaagggg cttaaaactt caaataaaga
      361 tgctgaatta ctagttaagt attcaaatat atttgaaaat cctgaatcag ctagaactat
      421 tgcaaaagaa atgagagatt ctgatagaga tgttgtattt tcagctacag aagatgatag
      481 caaaagagct attcaggtgg caagagaaaa tggtggtaaa gttatagcta ttaataaaga
      541 ccaatacgat atggctccaa ataatgtaat aagttcaatt ataaaagatg tagagcaacc
      601 tgtctatgaa ctgataaaga atgttgtaaa agatggtttt aagggcaata aggtaatgga
      661 atttaaaata aaagatggag aacttggttt gacttcaaag agtagtagaa atataccacc
      721 agatgttttg gaatatataa aaaaagagta taacaaggtg aaagatacat attaattatt
      781 gatgtagaag attataaaaa tatactttat taagtttaga ttaactatat aaaattataa
      841 caataagtgt gtgggcagaa aaattctgct acacacttta tttatattca tataaaaaaa
      901 ttatcaaaaa aaagaaaaag gagtaaaaaa tggaatttac aagagaacca tttatactag
      961 atgacgattt gtgtctagct ttggtggaca aaagaattag ttatctaatg gaaaatgaat
     1021 taaaattaag aaatatagag ataataaaaa cagtagaatg taaagaatta tatgaaagca
     1081 taaaatatca cccagatata tgtatttgta atttaggaaa aggagatata attgttgcgc
     1141 cgaatgtata taatcaatac aaagagttat taagtagata taaatttaat ataattaagg
     1201 gagaagctaa tttattaaat agataccctt atgatatacc ttacaatatt gcgatagttg
     1261 gtgattatgc tatacacaat tttaagtata ctgacaaagc aatattagat tatattgaaa
     1321 ataataaact taaaaagata aatatagagc agggttattc taaatgctca atctgtatag
     1381 tagatagaac atctataata acatcagata aaggtatttg gaaaagtatg aagaatacag
     1441 aaatagagtg tttattgata gaaaaaggtc acataaattt atttgagatg aattatggat
     1501 ttataggtgg atgtacaggg ttgatttcta aggataaact agctttttgt ggagatgtta
     1561 aaaaacatcc tgactatgaa cgtataaaaa gttttgtaga aagtaaaaac aaggagatag
     1621 ttacacttag ctgtgaaaat ttactagata taggttctat agttcctctc atgacaagaa
     1681 aggagcgata actttggttg agaaggataa tatttcttcc atgaaatttt tgaggaataa
     1741 taatgtaaac gatagattaa tatatacgaa tgatattgta gaagtagtga tagattctgc
     1801 aaagcaagaa gtattaaata aaaaaatact taatggtact aaagctgaac aaagagcttt
     1861 aaatattgat gagatatcaa cggaaataac tagtatgata ataagtataa tgaaagagaa
     1921 acttttgaaa gaatacattc taaaatgcta tgggcgtaca tatcctgaag ataaaaataa
     1981 tatatacata tattcactga acatatttgc taaaaaagag atttttatga gagaaacagt
     2041 atttacgagg gtgagaaatt atatagaaga aaatgatttt ataaatgtag aaggttttat
     2101 tagatttaga atgagagaat ttatgaaata tatttctgct ataggtgata ttgcagttga
     2161 agagtattta ataaagaaag accaagatga atttataaga gttttaaaat actttataga
     2221 tactcaagaa gaaaagattg atttgcttaa agttcatata atggaagaca atacatttgt
     2281 tttatacgat aaaaatggaa ataagataga tagcatagat gatgaagaaa ttataaatat
     2341 ggtaataaga gaaaatttaa attatgagga ctttctaata agtaccttgt taactctatg
     2401 tcctaaaaaa atagaaatat tggatttatt aaataataat tgctcaaagg aaattataga
     2461 tactgtagaa gcaatttttg aaaataaagt tagtataatt atggaaaact agaatctagg
     2521 tgtataagag ttagccatat aaaactaaaa aaattctttt taaatcgaca caaaagactt
     2581 ataattgtat ataaagcata gtatagctag agctattaaa tataaagaat atctatttga
     2641 ttaatgcaat atagcttgca aatatacaat tgataaggag taattttata atggataatt
     2701 taattaggat actgatatta gctgttattg gtggatttat aggttatgtt acgaatgtag
     2761 ttgctataag actgatattt agaccaatag agcctattaa aatacctatt ttaaatatag
     2821 aaatagtagg tcttatacca aagagaaggg tagaaatagc agcaaatgta ggagaaataa
     2881 ttcaagaaga atttctttct atggatgaaa tacttgcaaa tatcattact gacgaagaca
     2941 aggaagaagt tgtaagatac ataaaagcaa gggtaaaaat tataatacat gagaaagttt
     3001 catttatccc aggtggtata aaaaacatga tacaagatta tctaggagag ataattgagt
     3061 ctgaagttaa gaaaagtata gatgaattga gtaaaaatat aataaataaa gcaaatgaac
     3121 gtatagatat acaaaaaatg gtcgaagata agattaatga actagattta tacgaattgg
     3181 aagagataat aataagaata gctaagaaag aattaaaaca tatagagttc ttggggcttg
     3241 tcttaggttt tttaataggt atagttcaag ggttagttac tatgtttatt taagtatatg
     3301 atacttattg actacattta ggtattaatt gtatttactt atttgattgt attacttatt
     3361 aactgtgctt aagtattaat tatatttatt tgactgtagt acctattaat tgtatttact
     3421 tatttaattg cgttgcttat taactgtatt taagtattta ctgtattact tattaactat
     3481 attaaatatt gattgtattt aagtatacaa aacctaaaag agtacaataa ttagaagtta
     3541 gttttaataa aaattagttt tagtatttat ctagtcatat ctatcatgca tgtggatatg
     3601 ttttaaaaat tttaaattta tgaaaatatt ataatatcac tataaatcaa gagattgatt
     3661 taatataaaa atataagaat attggtttac agatgattga gatgaaaaat aatgggtaat
     3721 taatatatta cattaatgtt gattgatgta taactatctg ttataatgaa aatatattaa
     3781 aaatcatagt gttgaagagg aagagtagag tagaaaccat tctcagagaa tttgggtcta
     3841 tggctgagag cccatgtaat aggtctattt gaaaactacc ttggagctga gctttattag
     3901 cagtatttgt atttatacta tatgtgaaag tgctcgggtg acgaccttat agtcatcaag
     3961 agggttgtat atacttgtat acgccaactt gggtggaacc gcgaattaat atcgtcccaa
     4021 atatatttgg ggcgattttt tattacaaaa aatctaaaaa ttatttcaat aaggaggaaa
     4081 aaacaatgat taaagttgct ttaaaagatg gctcaataaa agaatttgaa aatgctattt
     4141 ctgttatgga tgtagctaaa tccattagtg aaggattagc tagaaatgtg gtagcagcgt
     4201 ctgtgaacgg agaggttgta ggtctggacc acattataga tactgattgt gacttgaatt
     4261 tatttaagtt tgaagataaa gaaggtaagg aagtttttag acatacatca gcacatatat
     4321 tagctcaagc tataaaaaga ctttacccag aagcaaaact tgctatagga ccaagtatag
     4381 aaaatggatt ctactatgat atagatttag accatagatt agttccagaa gacttagaaa
     4441 aaatagaagc tgaaatgaaa aaaatagcta aagaagattt aaaaatagag agatttgagc
     4501 ttcctagaaa tgaagcttta gagcttatga aagaacaagg agaagattat aaggtagaac
     4561 taatttctga tttacctgaa agtgaaataa tatctttcta caagcaaggt gattttactg
     4621 atttatgtag aggaccacat ttaccatcta ctaaaaaagt taaagctgtt aaattacaaa
     4681 gtgtagcagg tgcatattgg cgtggtgacg aaaataataa gatgcttcaa agaatatatg
     4741 gaacttcttt tgagaaaaac aaagacttag aagaatattt acatttacta gaagaagcta
     4801 aaaagagaga ccacagaaaa ttaggtaaag aattaggatt atttatgata cctgaagaag
     4861 gtccaggatt ccctatgttt ttaccaaaag gtatggaact taaaaatgaa ttattaaaat
     4921 tctggagaga aatacacaga aaagctggat atattgagat agaatctcca atcatattaa
     4981 atagaaaatt atgggagact tcaggacact ggtatcatta caaagaaaat atgtatacag
     5041 ttaaaataga tgatgaggat tatgctataa aacctatgaa ctgtcctggt ggattaattt
     5101 actataactc tcaactacat tcatatagag atttcccaat gagagttgca gagcttggta
     5161 gagttcatag acatgagtta tctggtgcat tacaaggatt aatgagagtt agagcattta
     5221 ctcaagacga ttcacatata ttcatgttac cagagcaaat taaggacgaa ataaaaggag
     5281 tagctaacct aatagatggt atctacaaaa cttttggatt tgaatataat ctagaattat
     5341 ctacaagacc agagaactct atgggaagca acgaagagtg ggaagcagca gaaaatggat
     5401 taagagaagc tttagaagaa ttaggtttac catatactat taatgagggt gatggagcat
     5461 tctatggtcc taagatagac ttccatctaa aagattgttt aggaagaact tggcaatgtg
     5521 gtactatcca attagatatg caacttccaa gacaatttga taatacttat attggacaag
     5581 atggtgaaaa gcatagacca gttatgattc atagggttgc ttttggtagt atagaaagat
     5641 ttataggtat attaatagag cattatgctg gtaaattccc agtttggtta tctccaactc
     5701 aagttaagat acttcctata tctgataaat ttatggatta tgcaaatgaa gttaagaaag
     5761 aattatttga taagggtata agagttgagt tagatgatag agctgaaaaa attggattta
     5821 agataagaga agctcagctt gaaaaagttc catacatgtt aatagtaggt gaaaaagaag
     5881 tggctgataa taatgtttct gttagatcaa gagataaagg tgaaataggt agtattaaat
     5941 tagatgaatt tatagctagt atttcaaagg aaattgaatc aagagaaagt attattcaag
     6001 actagtatac aagatattag tagctaagat attattatat aagataaatt taatcaatat
     6061 gttgatatat agtgattaaa tttatgaaaa gatgagtata attagaggta cagttaatca
     6121 tatttttatg attaatgtac ctctagtttt tttgtatggt agatttatta ataaatatat
     6181 catagaagtg ttttgaatct ggaaatttta aataaaaact tattttttga gtgataatta
     6241 agtgcttgtt gataaggcta tggctgtaaa aatcataacc ttattttcat atttgttcca
     6301 ttttcatgaa aattattatc catttaagaa aatttcttaa tccttttgaa atatttcatt
     6361 tttagtctag acttaaattt ctttcttcaa aataaatgct taaatgaatt aaaatttagg
     6421 tttattttct aatcttatga gtctattttt cataaataat taccttataa tagaagaagt
     6481 tatgttgggg ttatgtgcta aaaataacag cattgtcaat gattaattaa tattttatgt
     6541 tatttttaga tttatcttct atacatatat taatttattt aactttagtt atagagagaa
     6601 tgtcgagtaa atacacagac attagagtct aagaaggtgt ttatggaaca agagttttta
     6661 aaagagatag ctaattagtt taatgtcaaa aaatgataaa tacaaaagag gaaaaagaga
     6721 ggtgtttaaa tgatagaaaa agtaggagaa aaatctaaga ttattaaaac atcaaaagaa
     6781 tataagcgaa ctataattga agaaaaagat agagaatgga ctcaaaaatt aaacgacata
     6841 cttagtagaa ataatttttc taatgatgaa ttagacaaaa tcaaggagtt aattccaaaa
     6901 gagattttga ctagtgaaaa tgtcggagaa gttgtgactg aagatggata tgctagacct
     6961 gaatatgatg aggtatttaa atcattgttc actttaaata atgaatacgg tttacttgta
     7021 aattttataa atgatattct aaaagatgct ccatatgcta acaggaatat caaaccgttt
     7081 actcaaataa agagaataat tagacttgaa actgacccaa caattaatta cattggagag
     7141 aaaaggccta gacttgatat tttggctgaa gatgaagaaa ataatcatat aaatattgag
     7201 atgcaaagag cttttgaaaa tgattatttg gaaagagctg aatattatct tagtcgtgta
     7261 catggtagaa agttagaaga aggtaaagaa tataaagaaa ttggaaaaac tattggaata
     7321 catatactaa atcatgtaaa atataatcac atagaagatt atgtaaattg cctgagatta
     7381 acaatggatg ggcatccaga gatttattct agtaaaactg cattatattt tatagagctt
     7441 ccaaaaattc ataaatctga ctatatagta aatagaatta tgctatgggg aaaacttatt
     7501 atcaatcctt ctagtttaga tgtaagggtt atagctaaga atgattctat tattaaaaaa
     7561 gcacttgata gattaaaaga attaggtagc aatgaagaat atttattaaa tctgaaaaga
     7621 ggtgcttata ttatgaataa aagtagaaat tttaaagaag agatagaaag agagacagca
     7681 attagagttg caaaagaaaa agattataaa ataattataa tgttgaaaaa aaatggtttt
     7741 aaattagatg atatattaaa caaatttaat gcttttgact taagcgaaga tgagataaaa
     7801 gaagtttatg aaaataatta atgtataaat aaaaagtgaa cttatacaag ttcattaaat
     7861 ctgagtctgg aaatatatat gtgtattttt taaataaaaa tttattttaa agaccataat
     7921 ttagaggtac agttaatcac actttcatga tactgtacct ctagtttttt tattgtaaat
     7981 ttattaataa atctacaata aaagtggttt tgttgtaata atcattatat ataatgatta
     8041 ttttttatag tgattaaatt ttcacttgta gtgcttaaat ataaatttgt aacactattt
     8101 ttataaatgt ataaatcact atgacgattc aactcaaagt cactgtacaa aacaccagaa
     8161 accttatatc aataagatgt tattgcacca gattgttcaa gtctacgaaa tgctgtatac
     8221 aaaatagctt ctttcaactc atacaatcct ttggtttttt caagtataga tttattaatc
     8281 tcataactat agctgtcttt tttaagtaaa tgttttaaga tacttgtttt tgtatcacat
     8341 cttataacat cagatgcgat tgtcatgaat atcacatccg attaaatata taatagtttt
     8401 atggactttg cttatcaagg tatatcatga aaaagacatt ttattgtaat atttataaga
     8461 ttttatatgg aaataatgta aaaactttat aaataatata ttttatacct agttatagat
     8521 aaatttatat agttattatt aaaaaaaaca ataaaaagtt taattcaatc tagcaaattt
     8581 agtgatataa ttaaaaaaga aaagaaatat ggatttattt ggaataattt tgacaatcta
     8641 tttactacac gtgtagagtc gtatataatt aaattataca taaaatataa aaaaataatt
     8701 tagtaatacg ttaggagaaa gtattatgat aaagtcaagc ttattttgga atattttcat
     8761 tgcgatatcc tttatgatag aatggtttct ttgtaagaaa atgctagatt atacaagtga
     8821 gaaaaagatt tctaacaaaa aaataaactt ttgtatagta ggtattattg tttttgctaa
     8881 cataatctat ttttttgatg cacctctaaa tataagagta attatatcta tgatagttac
     8941 tattgcattt tataaaattt catatgatgt taggtttata aagtctgtat taatatcctt
     9001 aatttattgg atgttactaa tagctataga tgctttgagt atatctttaa cagtttggct
     9061 taattctata aatgacatga gtaatatggg gacaggagat atatacagaa ttgaatctat
     9121 aatattagga aagatacttt tgatttcggc tttgttttta tatagagcct taaaaataaa
     9181 atttaatata gaaataaata aaaggacatt attttatata gttattccta tagtcgctaa
     9241 tatagcatct ttttttgtca tttttaaata catatttaat ctaaagtttg gtaacttaat
     9301 acataatttc caattcgttg tgatttctgt tgtattactt gtatcaagca tcactttgat
     9361 tttaattgct aagaaattac agcaatataa tactttagtt gtagaaaata atatgattaa
     9421 aaatactttg aaatgtgaaa atgagtatta tgaagatata gaaaagaaat atttaaaaac
     9481 tagattacta agtcatgata tgaaaaatca tatattgtgc ataaatgcta tgattaaaaa
     9541 aggtattgat gttacttctt atttaaataa tttacaggta gaaatccaga gtaatgactt
     9601 attatttaat actggtaatt ttatattaga tgctatatta agtgaaaaga aagaagtttg
     9661 tgataggaat gatatagaat taaaaatagg aataaatttt agttgttgtg aagctgttga
     9721 attagtagat atatgtcata tattttcaaa tattttagac aatgccattg aggcatgtaa
     9781 taaaattgat agtggaaata gagtgatttg tgttaaaggt gatattatgc aaaattttta
     9841 tctaataaaa gttgaaaata ctaagacgaa taagattatt actaaaaatg gagatatttt
     9901 gacagacaaa aaaggttctc ttcatggact tggaataaaa agtgtaaaaa actctgtaaa
     9961 taagtatggt gggaatgttg taattgaata tgatgataaa aaatttgtag ttaaaattgc
    10021 tattccactt agaaatgtga agaaagtggt taataatata atttaatata tgggagttca
    10081 atatatataa atttgatacg tagaagttta atgtaaaaat tttgtgtata ggaatttaac
    10141 atacatattt attttaatat atattgaagg tatataatta aatcatataa tgacatttgc
    10201 agtttgaaat tatttattga gtatgagaaa ttttcaaggt cagaaagttt atgactatta
    10261 tatattatat tgtttgtcgt atttattata gattatataa tgagtttaaa atattaaact
    10321 tttaatttta caaaatataa aaagaagttg catcaaaaag ataaatgctc tttaaagatg
    10381 taacttctat ggtatatgta tgaggagcta tattgccatt tctggaatca agcttctcat
    10441 agcttctata gttgtttgga taagcttatc aagttcccat ccaagcattt ctgcaccact
    10501 tcttatgaca tctcgagagc agccagcagc aaatgattta tctttaaatt tcttcttaac
    10561 agattttaat tctaaatcag aaacactctt tgaaggacgc attattgcag ctgcaccaat
    10621 taagccagta agttcgtcta cagcaaacaa tactttctcc ataaattgtt ctggtttgac
    10681 atctgaacca gttaatccat atccatgact tattgtagaa tcgattattg atttatctaa
    10741 atcaagctct gtcattaatt ctctttgttt aacacaatgt tcatcaggat acatttcaaa
    10801 atctaaatca tgtaaaagtc caacgatttc ccaaaattct actctttcag ggtcgtactc
    10861 ctttgcatag tatctcataa ctccagatac aatttgagca tgtcttatat gaaattcttc
    10921 cttattgtat tttcttaata tttcccatgc ttgttctaaa gttggcatgt aactcatttt
    10981 tatcactcct ctagctgaat attttgaatt tttataaagt ttattttcca ttgattatat
    11041 caatcaattt ccaaaacgtc aacatactga tacacaattt tgcagttaaa ttcagaaatt
    11101 agtgaaaatt aaatctttag gtctaaattc tttgtatcta aagtttttcg tttcttaatg
    11161 ttatctttga tataaatgct ataattaagg taataaatcc aactcctagt ataataatgt
    11221 acactctatc tgataataaa tcaaaaagtt taccatacat aacctgacca agaggcattg
    11281 caattgttgt tcctgcaaaa agaattgaca ttacttttcc taagagttca tttggagttt
    11341 ttaattgtat gattgttata gcatatattg agataagagt cgttgtaaaa aatattagca
    11401 tagatgatac gataaaaatt aaaaacggaa ctggaaatcc cgtatttaat ataaatggat
    11461 atactgaaaa tgccattggt atgaacataa gtgcacatat agtaaaggaa atgtacaaat
    11521 tagtgatttt tagatatttt gagaaaatac caatactaac agcagctact agagaactaa
    11581 aagaaattgc tccctctgct agaccatata agaagttact agctcccata gtgattttta
    11641 ctatatatgg tataccaacg attaacatag agcttaaaaa taagtttatt gctatagcta
    11701 aaaaaagtat ttttagtata aatctatttt ctttacatat atgaacaata ccatcattta
    11761 tatcaataaa tatagttttt ataatgttgc tggtttgctc ttgtttgata aaaggaatct
    11821 gtataaatat ctccataatt gcagatagaa agaaacttac acaacttata actataattg
    11881 cattaattcc aattacaccg tacaagacac ctcccaatac aggtcctgca atatttgtaa
    11941 gggatgcaac tccagctacg ataccatttg cattcattaa atgctcatta tcaactaaaa
    12001 gaggtgtact tgactgaaca gttggttgat acattgtgct tatgactgat aatatggtca
    12061 taataattcc tacaagtaat attgaaccat tattgttgaa taaaaagagt gctaagacta
    12121 acactgtaat actacttgaa aaatcaaaaa taaccattaa gtttcttctg ttgaatatat
    12181 cagcaatagc tccaccaata ggggagaata ttataattgg gattgaagat actgctagta
    12241 tagtagcaaa tatttctgct ttaccagtta tatcgagtat gtataaagac aaagcaaatt
    12301 taagtattga tgcaccaaat aatgagatta tttgacctaa tatcatcaag ttgaaatttt
    12361 tattaaaagt attcaaagat tttaccatat atatacctac ctatctaaga ttattaaaac
    12421 atttacaata attgctataa tagcaattac tataaggact ttttttctta ctttaatacc
    12481 taatattatt agaaatatag aaacgattat agataacata gagtaaagtg gcatgagctc
    12541 actgctaggg tctacaagtt ttgtgtggat atttagttta tcatttattt tgtaaataac
    12601 atcatttagt ctttgtatta attcaatcat attatccttt ctagttataa agaaatgttt
    12661 agaaaattta ttttaaatta ttactcaagt atatgttcta caagattgtc taccataaaa
    12721 tcaaatactt caatgtagtc atatccaata tcttctttta gcaataggct tgacagtagg
    12781 gcattgcaaa caccaaaggc tttttctttc tctattttta acttgagatt atgtctttca
    12841 attaagctat aaaaactttg tacattgttg tattcaagtt gtgaaagcat ctctttaggt
    12901 atcttattca ataaagtgat gtaatcagta ttatttggtg aatataagaa tgggttttta
    12961 tcatataatc gatacaacat ctttaaggct tttgcaaaac cttctttttg aggcatgtta
    13021 cctaatattt catctactga tgatataagt ctgttttgga ttccatttag tacttcaaaa
    13081 aataactttt cttttgaatc aaagaatgtg tagaatgtac cctttgcaat tcctgatttt
    13141 gaacaaagtt catcaatatt agtttttttg tatccatatt tagaccagtt gatttcacat
    13201 tctgaaatta gtctttttct tatattatct ttttctattt ctgtaaagct tttagccata
    13261 tttatcaatc ctctctgtat atacgtatta tctatgactt aaaatgtttt ttaagtcata
    13321 gatatatagt attgtttatt tataaatttg tcaagtgatt tatattatga gacttgtatt
    13381 aaaatttgat ttgaataagt ttcaagcgag tatgttatca aaatagaaaa gcgtagaaaa
    13441 aacgttaact ctaaaaaatt tttctaggta aacgtttata ataaaaagaa atgtttacat
    13501 aacgaataaa tggctataat ttaaatacac aaagttatat cagagagagg aataaaaata
    13561 tgtttaatga acttagaaca aaagaaaatg tatataaaaa tttaataaat ggaaaatggg
    13621 tagaatctaa ttcaagaaaa ccaatagaaa tttactcacc aatagataat tctcttgttg
    13681 ggaaagtaca atctatgaca aaacatgaag tagatgaggc tataaaaaat acaaaagaga
    13741 gtataaaagt atgggctgat atgcctgtat ataagagagc caatatattt cataaggctg
    13801 ctgatttatt gttagaaaat atagatgaaa tagctaatat actggtactt gaaatagcaa
    13861 aagacatgaa atctgcaagg gcagaagttg agagaacagc agacttttta agatatacag
    13921 ctgatgtagg aaaaaatatg gagggtgaag ctattagtgg agataatttc cctggtggaa
    13981 caagaaataa gatgtcttat gtttcaagag ttccattagg tactgtttta gctatatctc
    14041 cttttaatta tcctgtaaat ttatcaatgt caaagattgc tccagcactt attggtggaa
    14101 atgcagtagt attaaaacct gctacacaag gggctattag cgcacttcat gtggtagaaa
    14161 ttatgagaaa agctggtata ccagatggag tacttaatac tattacaggt aggggtagtg
    14221 agatagggga ttatgttgta acgcataaag gaattaattt tattaacttt actggtagta
    14281 ctgaagttgg tcagcatata tctaaaatat ctggaatggt gccattatta ttggaacttg
    14341 gtggaaaaga tgcggctata gtattagaag atgcagactt agattttgca gctaagaata
    14401 tagtgtctgg agcgtattca tattcaggac aaagatgtac agcagtaaag agaattttag
    14461 tacaggagag tgtagctgat aaattagtgg aaaaaataaa gccattggta gagaatttga
    14521 caattggaaa cccaaaagat gaagtagtta tcacaccact tatagataat aaagcaactg
    14581 actttgttca aggtctagtt gatgacgcat tacataaagg tgcaaagttg atagtaggta
    14641 atattagaaa aaataattta ttctacccaa cattgttaga taatgtaaat actgatatga
    14701 agattgcttg ggaagaacca tttggtccag tgcttccaat tataagagtt aaagatataa
    14761 gtcaagcaat tgaaattgct aaccaatcag agtatgggct tcaatcatca gtgtttacaa
    14821 gtgatattga tagggcattt tatatagctg ataagcttga ggttggtact gttcaaatca
    14881 ataataaaac tgaaagaggt ccagaccatt tcccattttt aggtgtaaag gcatctggta
    14941 tgggaactca gggagttaag tattcaatag aagctatgac tagaccaaag gcagtagtgg
    15001 taaatgttag aggattgtaa taaatagaga taaagaataa tagaaataaa aaataaagga
    15061 gttgtcttaa atttgatttt ttgtaattga attttaagtt caactccttt ttgaattttt
    15121 atatgctatt tcttagtaat tattttttaa taaatatctt aaactttgag attgatgaaa
    15181 tttgaacatg ataaatatct taaatttata gtcttgtttt ctaatgatga agcctatttc
    15241 tacttaaata gagcaatttc taaaatgaac atttttatct cgagtaccat atacaatgaa
    15301 aaaaattaac cttgacaagt gaccgatggt cgctgtatga taaataaaaa agaaacgacc
    15361 agtggtcgtt aaaaggaggt atcactctat gccaaaagga attgtgctta cacccgaaca
    15421 acaagcagaa cgccgagaaa aaatagttgc tgttgctttg agtctcatgg ctgaaaatgg
    15481 attccaaaaa acatcaatga gagaaattgc agttttagcc aacatgggaa agtcaagtct
    15541 atacgatttt ttcaaaacga aagacgagat tgttgtatac gcagttgaga aagaaataga
    15601 aaaaactatc caacaagttc ataggattat tgatgatgaa ctttcgccac aacagtgcct
    15661 tagaaaaatc atgcttaatc atcttagatt tccaaagcaa tatagaactg tactgatgtg
    15721 gttaaataca gaatctgatt atttagaaga agagtatcga aagagactta aagatgctcg
    15781 ttatgcatat caagatatta taaaatcggt aattgataat ggtgtgacca caggtatctt
    15841 tcgcaaaacg gataccgctc ttgtgacacg tttgttaatt aactccatgt tatcaatcag
    15901 ctacacgtca cgactatcgg atagttcgga aaaaatgttg gatgaaacaa tgaatatatt
    15961 tctgcacgga attatgaatg atggaggtga atgattatga tttattatgt tttaccacta
    16021 gaacataaac aagcaaccat tgaaattgtt ggtggaaaag gaatgtcttt atcaaaacta
    16081 ttgacagcag gcatccctgt gccagacggt tttcatgtta cgactgcttc ataccagatt
    16141 tttgttgaga cgaaccatat tcagtctcga attaataaac tgctagatgg tattgattcc
    16201 aataatacca gccaacttga agatgtatct aagaaaatag gggtgctttt ccataatgga
    16261 gaaatgccac aggaagtgtc ggacgcaatt aaaacagctt atgacggatt agggaacata
    16321 tcggtggctg tccgttcatc tgcgactgct gaagatttac ctgacgcttc ttttgcaggt
    16381 cagcaggaaa cttatcttaa catacaaggt gaggatgaag tcattgacgc tgtaaagaga
    16441 tgctgggctt ccttatggac agctcgtgct attgcttatc gtgtgaagaa taatataaag
    16501 cacgagattg tcgcacttgc tgttgtagta caaaagcttg cattttccga ttcatctggt
    16561 attatgttta cgttaaaccc aatcaatggt agacgtagcg aaatgattat taacgctgca
    16621 tgggggcttg gtgaagcggt ggtttctagc ttagttacac ccgatacaat cgtagtggat
    16681 aaggactccg aacgaattat atcgtatgaa gtggcaaata aagagattat gacggttcgt
    16741 acttcagaag gaacagaaga aaccatggtt cctgaaaggt tgagaaaaaa atatactctt
    16801 actcgtaatc aggtaatgca actgatacag cttggaaaga aaattgagaa gtattatcaa
    16861 atgcctatgg atgtagagtg ggcactggaa aaagataaat tgtacattgt tcaggctcgt
    16921 ccaattactg ttctgccacc ggaatgggta ttgccagaac aggatgttgt atacacaaag
    16981 ggaagtttgg cagaacactt accaaatcct gttacacctt tgttcgccac gcttggtctt
    17041 gaaatcgtaa accgtgcatc ggagctttta tggatagata tgtttggtaa aagtgcgaaa
    17101 aaactactgc caaaaaacgg ggcatacacg gttattaatg gatatgttta tctttctgct
    17161 aaatcaaagc catttttgat tgctatcaaa tccctttccc cacgctcttt acgtaggaca
    17221 cttatgaaca gcgttgcacg ctgggaaacg gcacgaaaag gatatgagga tgctattaaa
    17281 caatgggaag aaaagcctct gcatacgatg aacgcacatc aaattatgga gggtattcag
    17341 acaatatttt atgccgcatg tatttatttc acaaggattc agcttacgtt gcctgctgct
    17401 tctatcagtg aaacattatt tacaaaatta tttcaaggag cagttcgccg tgctggtata
    17461 acggatactt ccgttttcct gcttgggttt gatacgattg ctctgcaatc ggaaaaggag
    17521 ttatggggtc tttcagaatg ggtaaagcaa aataacagca tcaaccttta tctgcaaaac
    17581 agtcctgcaa taaagatagc agaagatttc atgtcttcag ttgtgcctgt tggagtttca
    17641 caggaagtat ggatagaatg gaaaaatcga attaataagt actttaaaga gtttggtcgt
    17701 accgcttatg aatttgattt tgcgtattcc acaccacagg agacacttac accaactttt
    17761 gaatccgtaa aaacatttgt ggaaggaaaa ggggaaagtc cttttttacg ccagaccacg
    17821 tttgaaaagc gtagaaaaca tgcagaagaa gagattttac aacacatagg tggattgcgt
    17881 aaaaaactat tttttaagtt gctccattgg gcgcaggaaa cctctcctat gcgtgaaaat
    17941 gctatttatt tgatgggaat gggacatcct ctgattcgct gtatgtttca ggaaatctca
    18001 gaacgattca tacgaggagg agctatttca catttagatg atatttattg gctcacaaaa
    18061 tcggaattgg aggcgcttat agagcagttg gataaaaata agtctctatc tgatatgaac
    18121 gggttaatac ctgttcgaaa agctgaactt aaaaaataca tgggttatgt gtcaccatcc
    18181 aagttgccag agaaaaacaa aaaaactata tcacaagcac tacagaagca gaaagatggt
    18241 aaaattgtgt tgacgggtat tggtaccagt actggtgttg tgacggctcc agcttgtgta
    18301 ctgaatagtc cagcagattt tgaaagcttt caacctggaa gtgttttggt tgcagttacc
    18361 acaactccag catggacacc attattttca tctgcaagtg cgattgtaac ggacattggt
    18421 ggtcctctta gccattcaag cattgtcgca cgtgaatatg gcattccagc cgttatggct
    18481 acacacattg ccacacgaac tatcaagagt ggacaaatga taacggtgga cgggttggca
    18541 ggtacggtga cgtttgatga gtaaaaagcc tattttcgct ttgaagcttt caacctttgt
    18601 gattgcgtta gcggaagtag taatacttaa agttttgaga tttaatcata ctactaatac
    18661 ccaccaaaca gcggtaagaa aaaccatagc tcggtgggta ttttcttatg caaaaaaatg
    18721 agagtgtatc aaaataaaaa tttgattaga aaaaatcaat tttgagacaa ttcctttatt
    18781 tgttaataca ataatatcac ttataataag caattttata ttgttaattg gaggagtttt
    18841 gaaacataag tttttcaaaa tcttttattg gtaaaggtct agagaacacg tatccttgta
    18901 acatatcaca gtttatttct tgcaagaaat ctttttgaaa actggtctct attccctcag
    18961 ctacagtggt catttttaac tttttagcca gttcgattat agatacaatt atatctcttt
    19021 cacgttgaga atctaaatgt tctgattgaa aaaatgctct atctaatttt aatgtatcta
    19081 cataaatatc cttaagcata ttgattgaag aatagccact tccaaaatca tcaatagagc
    19141 atttaaagcc atttttatga atttcattta ttatttcact aaatactttg acatcttcaa
    19201 atacaattgt ttctgtaatc tcaatttcta taaggtgaga aggaatatca tattttttag
    19261 ctattttatc atatgtcttg atgaaattat tggatgaaaa atgataacga gacatattta
    19321 ctgaaatatt tataggattt aatccatcat caatccattt ttttaaagtc ttgcaaactt
    19381 cctcaaaaac atataaatcc aactgtataa taaatccatt tgtctcaaat aatggaataa
    19441 attcgtttgg aggaattatt ccttcaacag gatgaatcca tcttactaaa gcttctgcac
    19501 cacatatggt ttgggtagat aactccaact tgggttgcaa ataaacttga aattctcttt
    19561 tttcaagtgc ttcatacatt ctattttcta tgctttgttc tagaataagt ttttccttat
    19621 cttttttact atagaaatta caaatacata aaccatgatt ttctacgttt ttaattgatt
    19681 tagaagctac atttgcacta tcttggatat ttgttatatc taaagaagta tcataaatta
    19741 catatgcacc agcagtaaaa taaagtatat atttataatc tgcgttatcg ttgaacctat
    19801 taatatgtgt aaccattgag ttcagtctag aagttatatc ttctggttta tcttttaaaa
    19861 gaagaataaa tttatcagca aagattctgg taaccaattc accctcatgt aagtgtttac
    19921 ttatacagtt gtagatatat tttaaaagct tatctccagc tatatttcct gctaaatcat
    19981 ttattaattt aaatttttgc atgttcaacc atattagagt atatgtaccc gatggtgatt
    20041 gactaataac ttcttttgct attatattaa actttgtatg attcatacca ccagtaacgg
    20101 agtcaataaa agctaatttc tctaattctt tattattttt ttcaataatc tcattttgtt
    20161 ttactaatgt tgttacatct gaatatatta aaagatatat aggtttacca tcttcccaat
    20221 ctatacattc agctacaact tgcatatgaa caatatcccc attgatattt tgtggagaaa
    20281 cagaaaaaca aacgtatttc ccagctttaa aatcactttg atatttgtac acagcactaa
    20341 gataactttc taaatttata tcatctaata gaaaatttac attatctttg aacatgtcaa
    20401 agtatttttt attagcatca agaagttgga atccaaagtc agtaacctta aacttggcaa
    20461 tgagacctgg aaaattgttg taagttacag tttgttctat tttaatcatc atttgttctg
    20521 taatatcaat cataacagag tatgaaatag gatatccatc aacgacttct cctgttaaaa
    20581 atccaaataa ctttatccat aatttttttc cattacggtg tttcatacga cagacatagt
    20641 catatttttt tgctccggtg gagaatgtct tttctacata ctctacaagt tcattccaat
    20701 cctctggatt atccttgtaa aagaggtcgc attgattgtg aaatagagtt tcgtactctt
    20761 cttttgtata tccgaacatt tcataataac ggtcattagc ccaaacaaca gtaaagtgtt
    20821 catctaatag gtgtttacta acacttacat ccagtgcatt cattaataaa ctgtattcaa
    20881 tatttgcaaa atctatatat tttgacattc ttagtactcc cttataacat atattttgta
    20941 gaatatctga actagctagt ttaaagtaga tttattttta agcttatttt catacatcaa
    21001 agaatctgcc tctgctatta aagtttcaat atcggatatt ccatcccact caactaatcc
    21061 atagcttatg gaaagagcat aaggatactc gtcggtatta cttaattttg ataattcata
    21121 atttatatca atcattattt tttctgcttc tatacaactt gtatcctgta aaaggaataa
    21181 aaattcatct ccaccatatc taaacagtaa ggaattttct acatttataa gtttttttat
    21241 tatttttgca gtagtggata tgtatttatc gccaaattgg tgtccaaagt tatcatttac
    21301 aagttttaat ctgtttaaat cggtaaaaca taaagtaaat ttgtagtgat ttgacatcca
    21361 ttctgatagt ttttgattta caaaaggtct attgtagaag cctgtcagta aatctgtata
    21421 tacaatatca ttcaatttat taatttcatg ttctgttttt atgctttcta aatattctag
    21481 ttggttttta atatcataac tttttatttg agtaattcta aaactatatt tttctgcaat
    21541 atagttacct accaaaacta ttatggcaga cttaattcca tataatttta aaatcaatac
    21601 atttccaaca gtataatata ttgatagact taaacataga tacaagtaca ttacaaacat
    21661 aaggcttaat aaaaaattta gatttttttt gtcctctaaa actgtgtcaa aattaatctg
    21721 attattttta tgatttttat aacagaaata tagacctgta actataaagc tagatgatat
    21781 agaatatact cggtaaatat ttgtaatgta attactgtca aataaatatg ctggcatatc
    21841 taatgttatt gacattaaag acctaaaaaa tatgtttatt gccaaaccaa taatagaaca
    21901 gtttagtgaa taaaaaagat tttttattat agaggttttg taagttattt taatttctat
    21961 gaataaaatc aacgtaaaaa tcgtccaatt tataattaga tgtaacctta aataagtaca
    22021 aataataaaa attaaataat taaacagaga gtatataata tatactttat atttattttt
    22081 agagttacta atcattatat cgagatattt aaaaaagtta taatgataaa ggtaataaga
    22141 taaaaaacat attaaaatta taagtaatct catatacata tccattttag ttactgttcc
    22201 ttttatgatt attttgttta ttagtgtaca tcctaatatc agcaatatta ataatttctt
    22261 ctacagtcat tttgttttcg ctaggaactt ccacaatacc atagctaaaa gatatcttat
    22321 tatacatact tttacgtatt ttctctataa attcttttgt agtgttttca ttagatttag
    22381 gcataataac tataaactca tctcctccta ttctggcgaa tatatcatct gcttttaaat
    22441 ttgaaataat tatacttgaa aagttaataa tatagttatc accagctaaa tgtccatatt
    22501 tatcatttat tgtctttaat ttgtctaaat caatatatat caatgaaaat aataaactat
    22561 tatcaatgta atgttgtatt ttttcaaaag caaattttct attatatgct gatgttaatt
    22621 catcaatgtt tgcttttttc tttaataaat tgacttttaa taattgttct tgctttatca
    22681 tttttagtct attatgttct ttttctaaat aaatattttt ttcaatggaa tatatatgat
    22741 tgatgaatat aatcatttgt aatgataata atatgttact tcctaatata aaataagaag
    22801 ttaaagcgct tggtggagaa aatgcaattt gtatactatc gaataatata tatcctaaag
    22861 tgaagtagat aaactttaaa aatagactaa attctatttg attttgagtt attacataaa
    22921 tatgctcttt tattttatcc atagagtacc ataagataaa atctaaaata gaagctatta
    22981 aaatactaat tatcctagat gacatattta caaatattat atctggactt gtattttcga
    23041 caattgacat tatacttata gtaataagat gtaaaataca aaaatttatt actgctatat
    23101 taggaataaa gtgtttgtta tcagaatttt ttatgctaat taaaagcaat ttatgactta
    23161 ct
//
LOCUS       DBGJFK010000056        23120 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.056, whole genome shotgun sequence.
ACCESSION   DBGJFK010000056 DBGJFK010000000
VERSION     DBGJFK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23120
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.056"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(180..935)
                     /locus_tag="ACOIAP_002570"
     CDS             complement(180..935)
                     /locus_tag="ACOIAP_002570"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HGZ2639451.1"
                     /translation="MNEKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKACE
                     KFGNIVGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDKDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEDYYEKKYFPYTMPISDIMGLD"
     gene            complement(1223..3610)
                     /locus_tag="ACOIAP_002571"
     CDS             complement(1223..3610)
                     /locus_tag="ACOIAP_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2639452.1"
                     /translation="MINTTKIAKNNLKQNKSKSILIIITIILSTLMLSSIGIYIVNAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFVKGKLPTKENEIVLDSGALKALGYKNKDLGERIKISYNDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRNMSQEDFNIYVKFNDKSNLSI
                     EQIKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGISIPIGIILGYVLANIIIK
                     SFMNIDAKSSQLPVILLVAVISFISVVLSLLKPMKVASKVSIVDAVRYSGNKISNKNK
                     RKGYKNINLNRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKNNLNILQMDNPLSKDFFNQIKNIEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLSKNLIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTKEG
                     KYQEVKDSIKKIAKSNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAISYTSGMMIGSILFGGILGYIAV
                     MVLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            complement(3603..4286)
                     /locus_tag="ACOIAP_002572"
     CDS             complement(3603..4286)
                     /locus_tag="ACOIAP_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639453.1"
                     /translation="MKILYTENLSKHYGKGESLVKALDNVNLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDETFIKELLKSLGLENKRDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGK
                     VLKVGDKND"
     gene            complement(4403..5713)
                     /locus_tag="ACOIAP_002573"
     CDS             complement(4403..5713)
                     /locus_tag="ACOIAP_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2639454.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSILSILIVTIIFLLFEYSR
                     LYKLYEHQIKNTQNIAGILIEKYPNDEVDIVKSIYNSNYSKVPIGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKNLSKIYFIVDKMAQE
                     NYLKDTTVSEETGYLVEYNEYFKEGTFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILDAVKSVTPKAKNKSITLNLNEFDSRIVPHDKKWTEESI
                     FNVLDNAVKYTQINGEINISVEETANYFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            complement(5707..6414)
                     /locus_tag="ACOIAP_002574"
     CDS             complement(5707..6414)
                     /locus_tag="ACOIAP_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639455.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFSIEEAKSIFAKE
                     EICLIISDIGLPDGSGFDFCEEVRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIVRADNKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSAPKYIK
                     TVRGVGYIWGERSIKKC"
     gene            complement(6720..8561)
                     /locus_tag="ACOIAP_002575"
     CDS             complement(6720..8561)
                     /locus_tag="ACOIAP_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HGZ2639456.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLDRFEEITIFHTNDIHGRY
                     AEGDEHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMGKGKNAVELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGRKVFDSNDIKEINGVKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVSELKEKGADVIVAICHIGTNTLSKPN
                     SIDIANKVQGIDLIIDGHSHTKFENGKQVGDTLIVSTGQYLENIGEVKLTLDTDDVGN
                     IKIENKSARLIGKEEALKYKLDSSVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITIRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKIYPEKSSAFLQVGGISYYFNPKQKEGERITSIQKEGKPLDLD
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVTEYIEYKREISKNVDGRIGIK
                     SKDELISENQESDLILSENKESINDNEENLSNNIKSSDSDKNKILDKTRTRESSNLGI
                     SKREAREKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKNKKSK"
     gene            complement(8774..9658)
                     /locus_tag="ACOIAP_002576"
     CDS             complement(8774..9658)
                     /locus_tag="ACOIAP_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HGZ2639457.1"
                     /translation="MKVLKKITILSLIILTLVGCSNGEDKKVVEGSKKIQNSKKNEQP
                     IIVHKDANILKDRYEPPKGFKRVNVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWVQGY
                     RISVNDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            9866..10783
                     /locus_tag="ACOIAP_002577"
     CDS             9866..10783
                     /locus_tag="ACOIAP_002577"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGZ2639458.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILVDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPIGIVDCIRSMR
                     NLVEYIPYTLKIIENPQGSFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKKYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKNSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDTP
                     SIYLENATNVFENTILGEDRLSLHLNFDE"
     gene            complement(10912..12246)
                     /locus_tag="ACOIAP_002578"
     CDS             complement(10912..12246)
                     /locus_tag="ACOIAP_002578"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HGZ2639459.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFDDADELLARTPEKLREAGIDLNIFREVIEVDSESKKIKVKNVKTGEIYED
                     YYDKLMIATGARSIMPPIKNINLKNISTLKSLYDGEYLKKLLSNDENRRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEITDVLEEEINRHNVNLHLDEVVVELY
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSSTNIKMLKNGAIIVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITERKAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVVLGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            12586..13974
                     /locus_tag="ACOIAP_002579"
     CDS             12586..13974
                     /locus_tag="ACOIAP_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HGZ2639460.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKENNLGTLTFKSLGMLLATTAIAAIVGIVVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLVFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     INKEVFSKKNIS"
     gene            complement(14055..15263)
                     /locus_tag="ACOIAP_002580"
     CDS             complement(14055..15263)
                     /locus_tag="ACOIAP_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639461.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNICYSGKDMIQEIKNSVAE
                     KSSLKDTISSIDNKVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGIIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNEAA
                     DNFLNQLKKYDVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKENYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLNLMDGQSDKYFTYLLGNRPLVKIKNIENPE
                     GLKVLFVKDSLIVPTAAFFSSVCSNIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(15279..16697)
                     /locus_tag="ACOIAP_002581"
     CDS             complement(15279..16697)
                     /locus_tag="ACOIAP_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HGZ2639462.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYTFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMITSIIMNYIFGLLVDKYRESKIKVRIFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELINTQLTIPNIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRAPNLKEAYNYFKAMFGG
                     NGVIWSDYTYMFLKEYWIFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            complement(16715..17791)
                     /locus_tag="ACOIAP_002582"
     CDS             complement(16715..17791)
                     /locus_tag="ACOIAP_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639463.1"
                     /translation="MKTLKVFFCSAKYFILVFIFFINASFISLATGDKILDLSFKKIE
                     TDLSSKITYEDTGVKIEIDSSKRDKERYLYIYQNIKENWSMYHNFCIEIQNKNKSSQR
                     INLSIQSKNMLEFRLKEGSEIFLEDRNIIYSDKINDGCIEVPGEFEGKIYVNFNNLIN
                     EKSNVVLDSNTLSNIVSWGITFIPSDEEHNIVTIKKLSLLSQEKLRFLNNIKIIGDEE
                     VQIPILGQSISQYEVLGLGSNSKIKYSLIGKQNNVNLSQNGKLTLSNKAKPGQIILQV
                     NVDDNFKFGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMKEINFMNSIITFIR
                     ILFVSLVVVCFGIYFYWRKCSKTK"
     gene            complement(17802..20108)
                     /locus_tag="ACOIAP_002583"
     CDS             complement(17802..20108)
                     /locus_tag="ACOIAP_002583"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2639464.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDRKKVHIYICDDGNREEMHVLAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPDVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLIFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKNKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYTAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEIEFRE
                     KSGNEMYIANMKAKIVNVVELNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRVNMNFQMDIKNIGKLRIVNFNYQYVLLTF
                     ENKNIYPKEIALEINEGIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTIIVSKPGEKKEKSIDEFEPMEYI"
     gene            complement(20113..21096)
                     /locus_tag="ACOIAP_002584"
     CDS             complement(20113..21096)
                     /locus_tag="ACOIAP_002584"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HGZ2639465.1"
                     /translation="MMFFLGIVLIVFYFVIRGNSDTVKMQRGINIGNALESPKDFHWD
                     VKMSNKFFDDIKDADFDTVRIPIRFSDYTSDSDDFKIDEEFFKKIDGYINYALDKDLI
                     VVLDLHHFEEIMKEPGAHKEEFLKIWEQISNRYQKYDKKLVFELLNEPKENLSSQLLN
                     EYIEEAIKIIRKTNSKRTIIVGPYNFYQIDYLNELNIPKDSNIVVSFHYYEPNDFAFQ
                     GNIYHKGFEHLRNITWEGTNEQMNYLKKRFDIVENWANKNKVKIFLGEFGITKEAPEA
                     SRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGNWDRDILSALIEKR"
     gene            complement(21394..22875)
                     /locus_tag="ACOIAP_002585"
     CDS             complement(21394..22875)
                     /locus_tag="ACOIAP_002585"
                     /inference="COORDINATES: protein motif:HMM:NF024716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HGZ2639466.1"
                     /translation="MGYVQDDTKAFVNDAILRDKDVLVEQYLPQTFWIEGQVPEDFKE
                     NNLNIGIDIFKSFGYEDEEKFCTIDVPVKVKNVVLKPLNESKFFLDLWQHPSCLARMY
                     KVELWSDIHFEIIDNYLKELASLGEKVATVIVSDYPWAGQSCYKVYKNPSNLYEYNMV
                     SVSKGLDGKIKCNFESMDKYISIADKHKMAQEIDLFGLLGNWCAGEFGNPVEGYKDPI
                     RVRYFDESDKVFKFINNTDDLKEYIGLVLNHLIECGLWDRVRIIADEPNNPEVVKECI
                     EFINSTVGTHQVKYKSATHDQNFLDRAKDEIDDMSINLKLTIQNYKDIENLKKKINNN
                     GGILTWFVCCFPEKPNSFISSPFVENRIIGWYTYYFGLDGFLRWDYNLWTEDPWKDSS
                     YKFPIWKAGDMFFVYPGKDLKPVRSVRVENLRFGIQDFELFTMLEKEKGREYIEVELM
                     QELLNKKENAEIKGFGDIELGYSLDNCGYDKVKKYVLELLERL"
BASE COUNT         7594 a         4014 c         2356 g         9156 t
ORIGIN      
        1 aactttcaca cttaggttta tttcatcctt atgttttagt ttggttagct ttaggggttt
       61 ccagcaattc aagtagtatt gaataggttc tatcctatct ctacatatag gtttccctat
      121 atgctgacta atttagctac taactcatga ctaaagtcac aagtgtgcat agctattttt
      181 taatcaagcc ccattatgtc acttattggc attgtgtaag ggaagtattt tttttcataa
      241 tagtcttccc atatatttaa attacaataa aaacctatta catcagtttt tctatttttt
      301 atacaatttt ttgcatcttg acttattcca actatagtaa gacctgctgg tgcagaaata
      361 gctttttgcg aaccgcctaa tattatgtct attttagatt catctacact taatctttct
      421 cctaccatac ctgctacaga atcaactaca gttaatattc catattcctt aagtaatgga
      481 catattttgc ttacatcatt taatacacca gttggagtat cacaatgcac tactgttgca
      541 tatttaaagt tactatcctt atctaaaaat gctttcaatt catcaatatc tatactttta
      601 gtatattcac ttgaaaaaag cacatactcc ccaccataca ttgttacaaa atctttaaaa
      661 ccttctccat atataccatt atcaattaca agtactctat ctcccttttc tgtaagtgat
      721 gcacatgctg cttcaagtcc taatatccct tcaccactca atatgtaaac atcgtttttt
      781 gtgccaacta tattgccaaa cttctcgcat gcctttttat aaaattcaac aaaatcaata
      841 tctatatctg gatttgttgt tttttctgct cttgctaatc ttacattttc cctagtttca
      901 gttggtcctg gtgcataatt aatcttctca ttcatatata tcagctccta tttattttct
      961 atacgattat tatacaaaat tttcatttta tatggtacaa ttttatactt ttttagaatt
     1021 gtaccaatac attttctgac ataaataata taaatctatt atatatatta tttattgcac
     1081 aataaaatac agagcaaaca tcagtttaaa ttgtttgctc tgtaactata ctttaaccta
     1141 tttaattatg aatctattta accatctttt ttatatggtt tttgctagtt aaactaacca
     1201 taaatacata aatatttata ttttattcac tgtatcttac tctatcaata agagattctt
     1261 tattaaaact tcgtcctatc aaataagttg ttataaattg agctataaga atacatacaa
     1321 tcatcaacaa gattggtact attggcaaag aatacgttgc ataagataat ccagtcttct
     1381 ttagaaccat aacagcaata tatcccaata tacctccaaa taaaatactt cctatcatca
     1441 ttccagaagt gtaagatatt gcctctgagt taagcatttt caccaattgt ttattagtaa
     1501 gaccaatcgc ttgaagcatc ccaagctctt tctttctagt aactatgcta gttatcattg
     1561 tgtttacaag attcataaat ccaatcacac ctattatgcc tgttaatgta taacccatta
     1621 tttttataaa cgaaatagta gccttatttg attcaattct actatctata aaatctgtct
     1681 ctaaaaatcc attagattta gcaattttct ttatactatc ttttacttct tgatactttc
     1741 cttcttttgt atatattcct aaactacttg ttgaatcgta tttcaaggtt ctatctataa
     1801 aatcctttcc tataccaaaa cttggaactc ccatagctat tgcttgaact ttaaattctt
     1861 tttttatctt tttatctcca tcatataaag ttaatcttat tttatctcct gcttttactc
     1921 ccatttcttt tgctgtatca acatgagtaa ttactatttc atctccagtt tgcaatcttt
     1981 caagatttat ttttccatct attagattct tgcttaatga ttttacatca ttttcgttta
     2041 tactttgtaa aaggtcatat ttaaattcaa catcatagtc ctccatacca atttttacac
     2101 ttcttgcaga ctctattctt ttaattcctt ctatgttctt tatttgatta aaaaaatctt
     2161 tacttagagg attatccatt tgtaaaatat tcaaattatt tttaggattt ttatcactgt
     2221 tcatttcata accagataat ctaacttcta tatcataagg aaagtgttct cttgccatct
     2281 tctcagcatc aaaactttct aaagcagtcg atactgttat aaatatagtc ccactaagta
     2341 taagtgatgc caatgtcata taagtacgtt ttttatttct ttctaaattg gcatgtgata
     2401 atctatttaa atttatattt ttataacctt ttctcttatt tttattgctt attttatttc
     2461 cagaatatct tactgcatca acaatagata cttttgatgc cactttcatt ggttttaaaa
     2521 gcgataaaac aacagatata aaacttatta ctgcaaccaa taatataact ggtaattgtg
     2581 atgattttgc atctatgttc ataaatgatt ttattataat gtttgcaaga acataaccta
     2641 aaattattcc tattggtatt gatattcctg ctaatataaa tccttcttta aatactatat
     2701 tttttatttg ttttttagtt gcaccaattg ctctaagctt tccaaattct tgaacttttg
     2761 taactattga aatataaaat atattgtata ttactaaaat actagataat acaattacta
     2821 atcctacaaa aactccaccc ataatcgttt ccatatctgg ttttaaagca tttatataat
     2881 tttcatttac agcagtatta atagtatcca atcctatatc attagcaatt ttatctaatt
     2941 tttcttttat ttgctctatt gataaattac ttttatcatt aaattttaca taaatattaa
     3001 aatcttcttg tgacatattt ctagtatttc tcatatacga ttctgatata atagcataat
     3061 aatatttacc tgcttcagat atttcgctag tttttaagat tccacttata atgaactctt
     3121 tttcaatttt tttatcattt ttgtagtcat tataagatat ttttatcctt tcacctaagt
     3181 ctttattttt ataaccaagt gcttttaaag ctccactatc taacacaatt tcattctctt
     3241 ttgttggtaa ttttcctttg acaaattcaa aactatttaa tttcaaagca tcttcattca
     3301 tatatgccag agaaatattt gaatcatctt ccagtttttc aacacctact ccattcattt
     3361 caccagttaa ttcaacatct gcatgattac tcaatatatc agcttgtttt tcatccacat
     3421 ttgctaatat accttgataa ttacctgaat actttatagt attttctttt tgatatgctc
     3481 ctgcattaac aatataaatt ccaatagaag aaagcattaa ggtagaaagt attatagtga
     3541 ttattattag aatacttttt gatttatttt gctttagatt attttttgct attttagtag
     3601 tattaatcat ttttgtcacc aacctttaat accttgccat cttctatgaa tataactcta
     3661 tcagccattt gggctatact gtcatcatga gttatcataa ctagagtttg actatacttc
     3721 ttagacatag attttaatat actcataacc tcatcagatg ttttagaatc taggtttcca
     3781 gttggttcat cagcaagtat tatagctggt cttgtagcta atgctcttgc tattgctact
     3841 ctttgttgtt gaccacctga taatgtattt ggtaaaacgt cgcgtttatt ttcaagccct
     3901 aatgatttta aaagttcttt tataaaggtc tcatctactt ctctaccatc tagaccaatt
     3961 ggtaacacta cattttccca tacattaaga gatggaatta aattatagct ttgaaatata
     4021 aaccctattt ttcttcttct aaacacagca agttcttctt cttttaatgt aaatatattt
     4081 ttattatcta tatacacctt cccagatgta ggtatatcaa gacctccaat catatgcaaa
     4141 agtgtacttt ttccagaacc tgattttcct attattgcaa caaattcacc ttcatttatt
     4201 tctaagttaa cattatccaa agcttttact aagctttctc cttttccata atgctttgat
     4261 aaattttcag tatatagtat tttcataaaa ttatcctctc attctaagtt atattacccc
     4321 atattttatt aatttcttat ttctggagtt gtttatactt atataataaa tgtagaggct
     4381 tacattttcc tttcatttaa tattacatag ttgtaagaaa caaagagaac ttgctcccta
     4441 tccctacttt tgaagaaact ataatatttc caccttgttc ttccaaaatt ttcctactca
     4501 aatacaatcc taccccacta ccttctacag attcaatttc atcagcagaa cctctataaa
     4561 aacgtttaaa gatattatta aactcatttt tttcaattcc tataccatta tcctctatta
     4621 taattttaaa gtaattagca gtttcttcta cagatatatt tatttctcca tttatctgtg
     4681 tatattttac agcgttatct aatacattaa aaatactctc ttcagtccac tttttatcat
     4741 gtggtacaat tctactgtca aattcattta aatttaatgt tatgctttta ttcttagctt
     4801 taggggtgac actttttact gcatctagaa tagtattttt tatatcatta tcttcttttt
     4861 ttatgtttat catactaatt tctaaccttg atatgttcac taaagaattt attaaatttt
     4921 ctaatttatt tatagaagct ttgttggtta ataagaactc gttggcttca tcttcttcta
     4981 attcctcttc tataagtaat gtattgtata attttaagga tgctaaagga gtttttaatt
     5041 gatgtgaaat atctgttact aatgatttta cactttcttt ttctttttcc aacttaataa
     5101 actttatctt taaacttcta ttaagctcat atagacagtt atttatctta ctaaatgtac
     5161 cttctttaaa atactcatta tattctacta gataaccagt ctcttctgat acagtagtgt
     5221 ctttcaagta gttctcttgt gccatcttat ctactataaa atagatttta ctcaaatttt
     5281 tatttatata tcttataaaa taatatatta tacctataac tactataaac atcattaaaa
     5341 aaataaaaaa tgattcctta aaaaaagatt ttaagtataa gctaaaattt ttatcatttg
     5401 acattttatt ttccaatcca tagccaaatt tcttaaatgc cttttctcca ataggcacct
     5461 tactataatt agaattataa atagacttta ctatatctac ttcatcatta gggtattttt
     5521 caatcaatat tccagcgata ttttgagtat tttttatttg atgttcatac agtttatata
     5581 atctactata ttcaaaaagt aaaaatataa tggttactat tagtatagat aaaatagaat
     5641 atacaataac tcttctcatt atataatcat ctttcacact taaaccatct ttgaggttca
     5701 tattttttaa cattttttta tactcctttc tccccatata tatccaaccc ctcttactgt
     5761 ttttatgtac ttaggtgcag atggattttt ttcaaccttt tgtctaagtc ttcttatatt
     5821 tactgcaatc gtattatcat ctacaaaatt accactacta tcccacaaag attctaacag
     5881 ttgctcttta gtcaatgtct gcatagaatt ttccatcaaa tattttaaca atttagtctc
     5941 tgttttactt aaaattatct cttcttcctt attatctgct cttacaatca atttattttc
     6001 tatatagtaa aagaataaat catcacaaac caataaagta taatttttta ctgtatttac
     6061 ccttttcata agcgcattca cttttgatat taataccatc aaactaaaag gctttgtgat
     6121 ataatcatct gcacctaaat catatcctgt gacaatatct acctcttcat caagagctgt
     6181 caacattatt atgtaaacat cacttttctt tctaacctcc tcacaaaagt caaaaccact
     6241 accatcaggc agacctatat cagaaataat taagcatatc tcttcttttg cgaaaataga
     6301 ttttgcttct tctatactaa atgcactaaa aacattgtat ccttcttttt ttaatttaaa
     6361 actaattcct ctatttaaag atttgtcatc ttctaaaagt aatatattat tcatccacat
     6421 gtcctccatt atcatacgta ctagctaaat tatatcatac tagtaaaacc gtttttttat
     6481 caatttataa atatatcaga ggttgttaat atgatttcat ttacttgaat aaaaactaaa
     6541 aatactcata gtaccgtact atttagtgta attatttttc ataaaataca actttaatta
     6601 aaagtaatcc tgttaaagca taaaaacaaa ggaaattagt atttatataa ctaatttcct
     6661 ttgctgttta ctattatcta aaattaaatt actatctact aacttttgct cattaacttt
     6721 tacttggact ttttattttt taactctttt tgattaaaat tcaataagca tattaatgta
     6781 cttgaaacta taaatataat tatactattt gaaaaaccta aatctcctgt tttaggagat
     6841 ttttctctag cttctctttt agatattcct agattagaac tttctctagt ccttgtttta
     6901 tctaagattt tatttttatc actatcagaa ctttttatat tattagatag attctcttca
     6961 ttatcattga tactttcttt attttcactt aatatcaaat cactttcttg attctcactt
     7021 attaactcat ctttagattt aataccaatt cttccatcta cattttttga tatttctctt
     7081 ttgtactcta tatattcagt aactgcactc tctaagtttc caaattcctt taagattggc
     7141 tcttttgaaa aacaaggaaa ttcatctcca cctgaagcta tataatcatt cgttgcaact
     7201 acatactttt tatctaaatc taatggcttt ccttcttttt gaatacttgt tatcctttca
     7261 ccttcttttt gtttaggatt aaagtaatat gaaattcctc ctacttgtaa aaaagccgaa
     7321 cttttttctg gataaatttt tactccatgc tccaatacat ctttaatctg tgctcctgta
     7381 agttctttgg taactattgt attgctaaaa gggaatacat ctacaatatc tcttattgtt
     7441 atattgcctt tttctatcgt atctctaata ttccctccat taaacaaaga aatatcagcc
     7501 ttagttttat ctagtaaaat gtcacttatt aaattaccta aattagtttc ttttgtcctt
     7561 acattttcat atgaaccatc tagagtattt gtagttacac ctataacttt atctaatatt
     7621 ttttcttgtt gctcttttat ttcgtcaacc tttttactta cactggagtc aagcttatac
     7681 tttaatgctt cttcttttcc aatcaatcta gctgatttat tttctatttt tatatttcct
     7741 acatcatcag tatccaaggt tagttttacc tcgccaatat tttctaaata ttgccctgta
     7801 cttacaatca atgtatcacc aacttgttta ccattttcaa acttagtgtg gctgtgccca
     7861 tcaataatca aatcaattcc ttgaacctta tttgctatat ctatactatt tggcttactt
     7921 aaagtgtttg taccaatatg acatattgca actattacat ctgcaccttt ttcttttaat
     7981 tcacttactt gctctgttgc actttctata gggtttttaa actctaaccc ctccacattt
     8041 ttaaatccag ttttgctctt tgtttcctgg gttgagagtc caaaaaatcc tatttttact
     8101 ccatttattt cttttatatc attactatca aaaacttttc tcccattttc aaaaatattt
     8161 gatgataaaa attttaaagt attctctcct aaattagcac ttttagataa ctcaaacagt
     8221 ctatcttttc cataattaaa gtcatgattt ccaggagtaa tatagtcata tccagcacat
     8281 ttaatcaatt ccactgcatt tttcccttta cccatattta ctattggaag cccatgcaaa
     8341 caatctcctg catctactaa aattgagttt ggagtttctt ttttcaatgt agctagattc
     8401 cctatttgta tatgctcatc accttcagca tatctcccat gtatatcatt agtgtgaaaa
     8461 atagttattt cttcaaatct atctagccca taagaaataa aactctgact tgttgtaatt
     8521 agaattataa ttaccaaaat taaatatctt ctaatcttca atataaatta gcctcctcaa
     8581 attagtttta gctttaatgt aaaatataaa ttttacatta aactttttag ataaatatta
     8641 aactatagta aaattaatta gtataatttt taatatttat ctatcaattt aattttgtcc
     8701 atatccaatt agttttaatc taattacatt ttttcacatc tatatttttc ttttattata
     8761 taaaattatt attttaaaat cttttcaact ggtctctttt aaaagtccat tgaggtattg
     8821 tcaaatcacc ttcaaaatct aaactatacc aaggactcaa atttggattt ttacgattga
     8881 taagaagttg agtttgttgt gcaggcatat agctttgggc tatcataaat accttttctc
     8941 cagtcttctc attttctgcc atatccataa ttatacttgc atgtcctgga cttccaccaa
     9001 ctataaatac atctcctatt ttcatatctt caacttttac aggctccaat tctttttcaa
     9061 gagataacgt tcctgaatag gcaaacacta tatccataaa ctttctgaag ctctcataag
     9121 atgttgaata ttcagttgct ttataccagc ttgaaccact atcgtttact gaaattctat
     9181 atccttgtac ccattttgaa tacttcgcct taaaaccatc aacaaaatca aaacttattt
     9241 catcatatag tttattctga tacaagtatt ctgctctcat aagcataatt gcgtctgcac
     9301 attgatgtaa atctctatta ccaatatcaa catcaaatac actatcataa ataccttttg
     9361 attccttagt tcttccatca tagtacttta ctttctctcc ataatttttt agcttagtat
     9421 tcctaagaaa tgattcaaaa cttccttttt ctacattgac tcttttaaat ccttttggtg
     9481 gctcatacct gtctttcaat atatttgcat ctttatgtac tattataggc tgttcatttt
     9541 ttttagaatt ttgaattttc ttagaacctt caaccacttt tttatcttct ccgttactac
     9601 aaccaactaa agttaatata atcaatgaca aaatggtaat tttctttaat actttcatta
     9661 atttctcctc ctttaaattc tcctaaatat aatttttact ttttgctaca caaattttta
     9721 tacattgtta tataaaaact ctatttgaca atatttcttg actcaagtgc acatttattg
     9781 ttatatttaa tgttaaaata attataatag gatatcataa taaaaacaaa caacagattt
     9841 gtgttaattt tagaaagggg aaaaaatgat agatttaact ttacttggat gtggtggaaa
     9901 tgtacctatg ccaaacagat ttctatcctc tgtatttata aactataaag gtagaaaaat
     9961 attggttgac tgtggtgaag gtactcaggt atctatgaag ctaaaaaaat gtggctttaa
    10021 agatatagac ttaatctgta taacccattt acatggtgac catatatttg gacttttagg
    10081 gcttttatca acaattggaa atagtggtcg tacaagtgat ttaactatag ttggtccaat
    10141 tggaatagta gattgtatac gttctatgag aaatttagta gaatatatac catatacttt
    10201 aaaaattata gaaaatcctc aaggcagttt ttctttagat aataaagttt taaggaattt
    10261 agaaatttca acaatcagtt tagaacactc tatagagtgc ttaggataca gttttaattt
    10321 tagaagaaac cctaaatttg atatagataa ggcaactaaa aatgaagttc ctaaaatatt
    10381 atggaataag ctccaagaag gccaaaatat agttttagat tcaaaaaaat atactccaga
    10441 tatggtctta ggggaattga gaaaaggagt taagataagt cttacaaccg atacaagacc
    10501 tatagaatca ataccagatt tcataaaaaa tagtgattta tttatatgtg aagccatgta
    10561 tggtgatgac ttagatatat caaaagctgt tagaaacaaa catatgactt ttagagaagc
    10621 tgctaatctt gcaaaactag gaaatgtcaa acaactttta ctgactcatt ttagcccttc
    10681 tttagataca cctagtatat atttagaaaa tgctactaat gtttttgaaa atactattct
    10741 tggagaagat agattaagct tgcatttaaa ttttgatgaa taatttaata taatacttgc
    10801 ttttaaatat ttgaattaaa aatttaggaa tgaattttac catgacaaaa atattttagg
    10861 taaattcatt cctttaattg cttttcaatt atattagcta taatctaaac attatttaga
    10921 tacattccca gctacattta aaacatccca ggttcttgca aatggtggag cataacataa
    10981 atctaacatt ccaagttgac ttgtagtcat tttcccaaat atagcagctg ccaatacatt
    11041 tgctctttga acagcatcct taaaaccagc cacttgtcca cctaaaacaa cttttgtatc
    11101 tgcatcataa ataagcttta catatatttt atttcttcct ggataataat gagtttgatt
    11161 atagtcagaa ataaatttag atttaacatt tatacctaaa tctttagctt ttctttctgt
    11221 aattccagtt gatgctgctt ccatatccat aatttttata caacttgaag atagtgagcc
    11281 ttgataagat acttctcgtc ctgctagatt ttctcctact atcctaccca atttattagc
    11341 tccagtagct aaaggcacat atacattttc attgcttact atattcttta tagttgcaca
    11401 gtctccagca gagtatatat cctccacaga ggttctccca tattcatcaa ctattatagc
    11461 tccatttttt agcattttta tattagtact tgacaagaac tcggtgtttg gtctaacacc
    11521 agtagcaatt attactacat ctgtatctat ttctcctttg tttgttataa ctttttctac
    11581 tttatcttct ccataaagtt ctacaaccac ttcatccaag tgcaaattaa cattatgcct
    11641 atttatttct tcttctaata catccgtaat ttccttatca aatacttgtg gcaatattct
    11701 atcttctaac tgaatcacat ccacatcttt tcctaacttc ttacatgcct caactgcttc
    11761 taatcctata aaaccagctc ctattattgt tactcttcta ttttcatcat tacttaaaag
    11821 tttttttaga tattctccat catataaact ttttaatgta gaaatattct ttaaatttat
    11881 gttttttata ggaggcataa tacttcttgc tccagttgct atcatcaatt tatcatagta
    11941 atcttcatat atttcacctg tttttacgtt ttttactttt attttcttag attcactatc
    12001 gacttcaata acttctctaa atatatttaa atcaattcca gcttctctaa gtttctcagg
    12061 tgttcttgct aataattcat cagcatcatc aaaaaatcca ccaacaaagt atggtaaccc
    12121 acaagcacca aaagatacta tttcggtttt ttcataaaca acaacttcat actcaggttt
    12181 tattcttttt aattttgctg cagcactcat accagctgca acaccaccaa ttattattac
    12241 tctcatttta tctctccttt gatgtctagt taatttcttc acttatttta agctttttag
    12301 tttatatata ttctatgtaa acatttttta taataatttt tagttattta tttaacacat
    12361 ttttatttga aatcaaatct tatcaaagct attttttatt ttgttagcac aattcaaatt
    12421 ccttaaatag ttattatacc ctatttttct atatttaatc acatttttca aaattatttt
    12481 tttactctat ttaagcaaat tattgatata atattgacat ttttttaata tattgatatt
    12541 atttaaactt agaaaaattt atttttaaat aaaggagaaa aaacattgga aagttcattt
    12601 ttatcacaat ttcttatgat tacagatttt aaaacgattt ttttcataat cttacttcta
    12661 ggtacattct ttattgttag acaatttgaa aagaaaaaaa tcaaattttc attgagaaca
    12721 atatatgcta cagtactagg acttatattg ggaattataa tccaagcttt tgctggtttt
    12781 cctaatgata ccactcaagt cacttggcta caagaagtaa gcaagtggta tagtctattt
    12841 ggttctggat ttatggactt attaaaaatg ttagtagtac ctttagtttt cttatcaatt
    12901 ataaaagtaa ttataaatat gaaagagaac aatcttggaa ctctgacttt taaatcttta
    12961 ggtatgcttc ttgctaccac tgctatagct gcaattgttg gaattgtcgt tgcaaatata
    13021 atgaagttag gtgtaggagc taatatgcct actctagttg aaaatcaaga acttaaagaa
    13081 ataaactctc ttgtggatac tttaagagga ttactaccat ctaatcctgt aatggctatg
    13141 gcaaatggaa atattgtagc tacaataata tttgctacat ttatagctac ctcaataaaa
    13201 agattgagca aaaaacattt tgaaacaata aaaccattta tagattttat agaagcctct
    13261 tacaagataa ttgtaagtgt gtctatgact gttattaaat ttatgcctta tgctgtggtt
    13321 gctctacttg caaatacaat aacttcacaa ggtattagct caatagtatc tgttttacag
    13381 tttatattag ctctttatat atcagttgca atattattta tcatacattt agtttttata
    13441 actttaaatg gtctaaatcc tattacttat ataaaaaatt caactgaagc tttacttcta
    13501 gcatttactt cacgttctag tttaggaaca ttacctgtaa cgatagaaag cctcgtacaa
    13561 aaccatgggg ttgatgaagg tgtatcaagc tttacagcaa gtttaggtgc aaatatgggt
    13621 atgaatggtt gtgcgggtat atatcctgct ttaatggctg taacacttgc taatatggct
    13681 ggtgtaaaca tggatatgag tttttatgtt atgttgctaa ttgttataac aattagttcg
    13741 tttggtatag ctggtcttcc aggaactgct acaatggccg tttcagttgt tatctctgga
    13801 gttggtcttg gttcttattt tccattagtt ggtggtatac ttgcaataga ccctatatta
    13861 gatatgggac gtactatgat aaatgttaat ggtgctatgg tatcatcaat tactgtagga
    13921 aaatcacttg gaaaaataaa taaagaagtt tttagtaaga aaaatatttc ttaaaataag
    13981 tatgaaaata aatggctaac cttcaaccaa ttagccattt attttttatt ttgttagaaa
    14041 atttttttag gaatttactc acaaaatgga aaaaattctt ttgtaagatt ttggggatat
    14101 acagatataa aaacaaagtc atagtcatga gactttgcat attctagtat atctccatca
    14161 tagtatctag ggtctatcat atctatattt gaacaaacag aggaaaagaa tgctgctgta
    14221 ggtacaatta aagaatcttt aacaaataac acttttaatc cctctggatt ttctatattt
    14281 tttattttaa ctaatggtct attccccaac aaatatgtaa aatacttatc tgattgaccg
    14341 tccattaaat taaggtctgc attaaaagga tacgataata tcagactctc ttcaaatctt
    14401 ccttttagtt caaatttttg agatttagaa tctgtataat aagtataatt ggtcttaaat
    14461 ttaggataaa ttaatgtaaa atcatctata ccaccatata aaataccagt ctttcttccc
    14521 atagaaccaa gaaatgactt gggatataca attgaattat aattttcttt atctctataa
    14581 taatgatttt catctagatt catattgtat tttttattaa gttgctcaac taattctcca
    14641 aatgcccaaa aagaagtttc tactttccag tgatggtctg ttttaaaaaa taaatcatct
    14701 ttgggaatac cactctttaa gatattttct ctaaaatcaa tatagtccac atcatacttt
    14761 tttagttgat ttaaaaaatt atctgctgcc tcattgctat aagaataagg tatccctttt
    14821 ggaaattttg tcactccttt tatatactta tctggagtca ttaaataaac caatttagtg
    14881 ttttgttttt ccatttcatc agaaaacttt cttactctat ctgctatgat gccaactgga
    14941 tttggagctt tagcaaaata tgtataatgc atttttccag aagtatcttt tacaacacta
    15001 aattttgaaa actcattttt acccattaat ttttgtaaat atccataagt ttcaatgaat
    15061 gtatttttat atattacttt atcatttact ttattatcaa tagatgatat tgtatctttt
    15121 aaactacttt tttcagctac tgaatttttt atttcctgta tcatatcttt tccagaataa
    15181 caaatattaa agatagagaa agcgaataaa ataattaaaa acataattgc agttattaat
    15241 cttactttaa aaaatctatt catacttttc cctcccaact aaaaattaaa ataaataaat
    15301 ggattatagc ttccagttac taaatatgtt acagaaataa agaacaataa aatagctgat
    15361 ataggataaa atacattaaa tatcatacta tatttagctt gttcaacaac aaacttattg
    15421 attttcttcg ctataggtac actaaaaata aaagcaaata taaagaaaat ccagtattct
    15481 tttaaaaaca tatatgtata atcactccat atcactccat tgcctccaaa catggcttta
    15541 aaataattat atgcttcttt taagttaggt gctctaaaca atacccatcc aaaattaact
    15601 actaataacg cataaatatg ttttataaaa ttatgatttt caatcttttc aaacattata
    15661 aatcgctcta taattagaaa aacaaagttt aaaatccccc aaattacaaa tgtccattct
    15721 gctccatgcc atattccagt aaataaccat actataaaca tatttctaat cataatatct
    15781 ttatttgcta ctctagagcc tccaagcgga aagtatatat aactcttaaa ccacattccc
    15841 aaagagatgt gccatcttct ccaaaactca ctaattgatt ttgatatgta tggataatta
    15901 aagttctctt caaatttaaa accaaacata agacctaatc ctatagccat atctgaatag
    15961 gcagaaaaat caaagaatat ttgcagagta taggctattg aaccaagcca tgcaagtgat
    16021 gcagctattt ctccttgact attcatagtg taaatatagt ctgctactat agccatgtta
    16081 tttgaaatta acactttttt acctagacct gttataaacc tacaagtacc aatagaaaat
    16141 ttattccaag tttcttttct attgagaatt tgttctgcta cactctcata tctaactata
    16201 ggacctgcta ttaattgtgg gaaaaatgct atatataatc ctacataaaa aggattcttt
    16261 tggacttctc catgtctacg atatacatct ataacataag acattccttg aaatgtaaaa
    16321 aatgaaattc ctataggtaa aacaatatta ggtatagtta attgagtatt aataagttca
    16381 ctaatatttc ttagtgcaaa agccagatat ttaaatataa ataaaacacc tatattgtat
    16441 gcacacatca aaactaaaaa aattcttact tttattttac tttccctata cttatctact
    16501 aataaaccaa atatatagtt cattattata gaagttatca taataacaac aaatttcggc
    16561 tctccccaag cataaaaaaa taaactaaca gcaagcaata tcatgttctg tatcgttcgg
    16621 ttaaatctaa atgtataata taaaactaaa gttataggta aaaaataaaa taaaaaaatt
    16681 aaacttgaaa ataacataat tcaacctcct ctctttactt agtttttgaa cattttctcc
    16741 aatagaaata tattccaaaa cataccacta ctagagatac aaataaaatt cgaataaatg
    16801 ttatgatact attcataaag tttatttctt tcatatcttg tactgttggt gattgttcag
    16861 gagataccag tgtatatgga acaccatctt tatctttttt attaatactc caagattcag
    16921 ttaatgttat tttctttcca aatttaaaat tatcatcaac attaacttgt aaaataattt
    16981 gtccaggttt ggctttatta cttaatgtca atttgccgtt ttgagagaga tttacattat
    17041 tttgttttcc tataagagaa tacttaattt tagaattact tccaagacct agtacttcat
    17101 actgacttat gctttgaccc aatattggta tttgtacttc ttcatcacca attattttaa
    17161 tattatttaa aaatcttaat ttctcttgag acaataaaga taactttttt atagtaacaa
    17221 tattatgttc ctcatcagat ggaataaatg taattcccca actaacaata tttgaaagcg
    17281 tatttgagtc tagcacaaca ttacttttct catttataag gttattaaag ttcacataaa
    17341 ttttgccttc aaattcacct ggtacttcta tacatccatc gtttatttta tctgaatata
    17401 ttatatttct atcttccaaa aatatttcac taccttcttt taatctaaat tcaagcatat
    17461 tcttactttg tatacttaaa tttattctct gggaactttt atttttattt tgaatctcaa
    17521 tacaaaaatt atggtacata ctccaatttt cttttatatt ttggtaaata tataaataac
    17581 gttccttatc tcttttagag ctgtctattt ctatttttac acctgtatct tcatatgtaa
    17641 ttttagaact taagtcagtc tctatcttct taaaggataa atctaaaatt ttatcacctg
    17701 ttgctaaact tataaaacta gcatttataa aaaaaataaa cactaaaata aaatattttg
    17761 cagaacaaaa aaacactttt aaagtcttca ttttatctct cctaaatata ttccatgggt
    17821 tcaaactcat ctatactttt ttccttcttt tcaccaggtt ttgaaacgat aattgtctta
    17881 ttttgtaata tccaatccat catttcatct cttaaaaaga aattttgcat tatgctatca
    17941 atattattca ctttatataa gatacctctt tcatcaattt taccctcaca taaatcgcat
    18001 tctaatacaa taccttcatt aatttccagt gctatttctt taggataaat atttttattc
    18061 tcaaaagtta ataatacata ttgataatta aagtttacta ttcttaattt acctatattt
    18121 tttatgtcca tctgaaaatt catattgacc cttggacttc ttcgtgataa tgttctagtt
    18181 ttttcaatac gtttttttac attaatttgc aaatcatcaa aaaaacctag ttgattagat
    18241 attgtcattg gtaaagtagg tattctatca tgaacaatac acatccaatt atctatttca
    18301 ctatcttcaa tatgtgtaat gtaagctgca tatttccact ttgaatttag ttccacaaca
    18361 ttaacaattt ttgctttcat attggctata tacatttcat ttcccgactt ttctctaaac
    18421 tctatctcaa actcttcttc tggagaaata tattctggat tttctagcaa aaatgcaaac
    18481 ccattttctg atatatcaat cgtttttgaa gaaagaacat aagaattttg ctttaattta
    18541 aaatcaattt cagcagtata acgctcagac tttcttaact gttgtcttcc tgatataaat
    18601 agcgtagcca taacaaggtt aaaaaggttt ccaatcaacc aaaataatac aactgaatat
    18661 gtcattgaac tcattttaaa tattgctaca aacattttta aaattcctat aatagataag
    18721 accatataaa taaaatacgg tattccttgt aaaaacttat acattctatt ttcttctaac
    18781 ttattcttat ttgttactga aaatttattt ttagatattg caaatgtttc aagtattact
    18841 gctggcatta aagactgaaa cattatagtt tcatatatat tagtccatct agtattcctt
    18901 atattttgag aaaatatttt aagagataaa ctacttaaaa tatacattgg caaccaaaat
    18961 atcaatactt gaagtaatgt acattttact acaatcacat taaatacaga aaacaaaata
    19021 ggtgccatta tatatacaaa gcgttttata cttgcatacc aataagtaat tgaagaaata
    19081 taacttattt tctgccaaaa tcctaaacct ctcctaaaca aaatgtttag gcgtctacca
    19141 gtttgtatac atccacgtgc ccatctttca cgttgcttaa taagactttt taaatctgta
    19201 ggagataaac ctgaggcatg tacatctgga atagcataac atctataccc cttactttga
    19261 attaagatac ctgttgcaaa atcttctgta atagaataag tataaaatcc atcaacttct
    19321 tcgagtgctt cccttgaaat aactgtatta ctaccaccat aaattacaga atttgtccta
    19381 tttctagcca attgaatgtc tctgtaaaaa taatcttgct catttggaat ccttccctca
    19441 gagtgcagat taaattggaa caagtctgga ttataaaaac tctgtggagt ttgcacaaaa
    19501 ccaacctttt catactcttc tttttctcca tcttttttag cttgctcatt ttttaaaaaa
    19561 tatggtactg tagcaattaa aaagtcatgc attggtatca tatctgcatc aaatgtagca
    19621 atcaaaggtg agtttgtatg ttgcattgca ttatttaaat ttccagcttt tgcaccttct
    19681 ctttctgttc tagttatata atttacaccc attttttctg ctagaacatg catttcctca
    19741 cgatttccat cgtcacatat gtatatatgc acctttttcc tatctggata ctgcatatga
    19801 atacatccat ttacagtttt tctcaccaag tcaacagatt cattatatgt tgcaatgaat
    19861 acatctacat gtggataaag ttcttcactt ataattggtt tttcaggata ctcaatattt
    19921 gacataccat aataatgcac aaacatttcc atcataccca ttatctctac aaaaagaagt
    19981 attatcgcac agattaaggc aaacatccct tcttctttag gtactgtata aaaaattctc
    20041 cacaatatat atacgatatt agtaataata gttaaagtta taagtatctt ttttgaattt
    20101 ttcttcataa aatcacctct tttctattaa cgcgcttaat atatctctat cccaattccc
    20161 ttcaatttga ttgtatatac caaatccaga agcaagctcc caataagccc atgaaaagtt
    20221 tcgtttttca gcttcttctc ttacagcttt tatccaagct cttcttgaag cttctggtgc
    20281 ttcttttgtt attccaaatt cacccaaaaa tatttttacc ttatttttat ttgcccaatt
    20341 ttctacaata tcaaaccttt tttttaaata attcatttgt tcatttgttc cttcccaagt
    20401 aatatttctt aagtgctcaa atcccttatg atagatattt ccttgaaatg caaaatcatt
    20461 tggttcataa tagtgaaagg aaactactat attagaatct ttaggaatat ttaattcatt
    20521 caaataatca atttgataga aattatatgg tcccactata atagttcttt tagagttagt
    20581 ttttctaatt atctttattg cttcttcaat gtattcattt agcaattgtg aggataaatt
    20641 ttctttaggt tcatttaata attcaaatac caatttttta tcatattttt gatacctatt
    20701 agatatctgt tcccatattt ttaaaaactc ttctttatga gctcctggtt ctttcataat
    20761 ttcttcaaaa tgatgcaaat ctaatacaac tattaaatct ttatctaatg cataatttat
    20821 atatccatca atctttttaa aaaattcttc atcaatttta aaatcatcag aatctgatgt
    20881 atagtcagaa aaccttattg gtatacgtac tgtgtcaaaa tctgcatctt ttatatcgtc
    20941 aaaaaactta tttgacattt ttacatccca gtgaaaatcc tttggtgatt ctagtgcatt
    21001 acctatattt atccctcgtt gcatcttaac tgtatcacta tttcctctta ttacaaaata
    21061 aaatacaata agaactatac ctaaaaaaaa catcatcata atacctattc tttttatctt
    21121 actctccccc taacactgct atcttatata taatattatt caatccctat tataacaaat
    21181 taaattatat catgttatat acaattattg taatttacaa actttatagt gttgatagtt
    21241 ttaaaacatt aaatgcaact aaaaaacaaa aatctatctt gaaatagaaa taatcctttt
    21301 tcattattaa agtgatgaaa ctatatttga cttcacacaa aaagagtgtc tcatgaacta
    21361 aaaagttcat tttgagacac tccattatat tttttataat cgttctaaca actctagcac
    21421 atatttttta actttatcat atccacaatt atcaagtgaa tatcccagtt ctatgtcacc
    21481 aaaaccttta atttcagcat tttctttttt atttaataat tcttgcataa gctcaacttc
    21541 tatatactct cttccctttt ctttttctaa cattgtaaat aactcaaagt cctgtattcc
    21601 aaaccttaaa ttctccactc taacacttct aactggcttt aaatcttttc caggataaac
    21661 aaagaacata tctccagctt tccaaatagg aaatttgtag cttgaatctt tccaagggtc
    21721 ttctgtccat aaattatagt cccatcttaa aaaaccatca agaccaaaat agtaagtata
    21781 ccatcctatt attctatttt ctacaaaagg agaacttata aaactatttg gtttctctgg
    21841 aaaacaacat acaaaccaag tcaatattcc accattgtta ttgatttttt tcttaagatt
    21901 ttctatatct ttataatttt ggatagtaag ttttaaattt attgacatat catcaatttc
    21961 atctttagct ctatctaaaa aattttggtc atgggttgct gatttatatt taacttgatg
    22021 agttcctaca gtagaattta taaattctat acactctttg actacttctg gattatttgg
    22081 ttcgtcagct ataatcctta ctctgtccca taatccacac tctattaaat gatttaacac
    22141 taatcctata tattctttta aatcatctgt attatttata aatttgaata ctttatcact
    22201 ttcatcaaaa tatcttactc ttatagggtc cttataacct tctacaggat ttccaaactc
    22261 accagcacac caattaccta atagaccaaa taaatctatc tcctgagcca ttttatgctt
    22321 atcagctatg cttatatact tatccatact ctcaaagtta cacttaatct ttccatccaa
    22381 tccttttgat acgcttacca tgttatattc atataagttt gatggatttt tataaacttt
    22441 ataacaactt tgtcctgccc atggataatc tgaaactata actgttgcaa ctttttctcc
    22501 taaagatgct aattctttta aatagttatc aattatttca aaatgtatat cagaccataa
    22561 ctcaacttta tacattctag ctaagcaact tggatgttgc cataaatcta aaaagaactt
    22621 actttcattt aaaggcttta acacgacatt ttttactttt acaggaacat caattgtaca
    22681 aaatttttct tcatcttcat atccaaagct tttaaatata tcaataccta tattaaggtt
    22741 attttcttta aaatcttctg gtacttgacc ttcaatccaa aatgtttgag gcaaatattg
    22801 ctctactaac acatctttat cccttaaaat agcatcattt acaaatgctt ttgtatcatc
    22861 ttgaacatac cccaatatat ttatactaaa attattttct aagctattag gtacatttaa
    22921 tgctaatctt actctatttc ccagaccctt ccatgatata gtactgcttt tctgaacctc
    22981 ccatgactaa agtcacaggg ttcctgcttc atagaatttt gcatactaaa atatgtctta
    23041 ctaattctcc acaggctatc cccatagttc ctacggttct tatataagtt atttattttg
    23101 aattgttgtt agtcttaatc
//
LOCUS       DBGJFK010000057        22520 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.057, whole genome shotgun sequence.
ACCESSION   DBGJFK010000057 DBGJFK010000000
VERSION     DBGJFK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22520
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.057"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..540
                     /locus_tag="ACOIAP_002586"
     CDS             <1..540
                     /locus_tag="ACOIAP_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HGZ2639467.1"
                     /translation="DVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGV
                     EMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEG
                     GRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRF
                     SIREGGRTVASGVVATIIE"
     gene            908..1219
                     /gene="rpsJ"
                     /locus_tag="ACOIAP_002587"
     CDS             908..1219
                     /gene="rpsJ"
                     /locus_tag="ACOIAP_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGZ2639468.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1311..1940
                     /gene="rplC"
                     /locus_tag="ACOIAP_002588"
     CDS             1311..1940
                     /gene="rplC"
                     /locus_tag="ACOIAP_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGZ2639469.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1970..2593
                     /gene="rplD"
                     /locus_tag="ACOIAP_002589"
     CDS             1970..2593
                     /gene="rplD"
                     /locus_tag="ACOIAP_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGZ2639470.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNIIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2593..2883
                     /gene="rplW"
                     /locus_tag="ACOIAP_002590"
     CDS             2593..2883
                     /gene="rplW"
                     /locus_tag="ACOIAP_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGZ2639471.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTASFKKAVVKLTADSKEIEFFQGM"
     gene            2913..3743
                     /gene="rplB"
                     /locus_tag="ACOIAP_002591"
     CDS             2913..3743
                     /gene="rplB"
                     /locus_tag="ACOIAP_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGZ2639472.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3778..4059
                     /gene="rpsS"
                     /locus_tag="ACOIAP_002592"
     CDS             3778..4059
                     /gene="rpsS"
                     /locus_tag="ACOIAP_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGZ2639473.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            4091..4426
                     /gene="rplV"
                     /locus_tag="ACOIAP_002593"
     CDS             4091..4426
                     /gene="rplV"
                     /locus_tag="ACOIAP_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGZ2639474.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4450..5265
                     /gene="rpsC"
                     /locus_tag="ACOIAP_002594"
     CDS             4450..5265
                     /gene="rpsC"
                     /locus_tag="ACOIAP_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGZ2639475.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5301..5732
                     /gene="rplP"
                     /locus_tag="ACOIAP_002595"
     CDS             5301..5732
                     /gene="rplP"
                     /locus_tag="ACOIAP_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGZ2639476.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5734..5937
                     /gene="rpmC"
                     /locus_tag="ACOIAP_002596"
     CDS             5734..5937
                     /gene="rpmC"
                     /locus_tag="ACOIAP_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGZ2639477.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5961..6215
                     /gene="rpsQ"
                     /locus_tag="ACOIAP_002597"
     CDS             5961..6215
                     /gene="rpsQ"
                     /locus_tag="ACOIAP_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGZ2639478.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            6241..6609
                     /gene="rplN"
                     /locus_tag="ACOIAP_002598"
     CDS             6241..6609
                     /gene="rplN"
                     /locus_tag="ACOIAP_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGZ2639479.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6633..6938
                     /gene="rplX"
                     /locus_tag="ACOIAP_002599"
     CDS             6633..6938
                     /gene="rplX"
                     /locus_tag="ACOIAP_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGZ2639480.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6968..7510
                     /gene="rplE"
                     /locus_tag="ACOIAP_002600"
     CDS             6968..7510
                     /gene="rplE"
                     /locus_tag="ACOIAP_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGZ2639481.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEIISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7528..7713
                     /locus_tag="ACOIAP_002601"
     CDS             7528..7713
                     /locus_tag="ACOIAP_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HGZ2639482.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7746..8144
                     /gene="rpsH"
                     /locus_tag="ACOIAP_002602"
     CDS             7746..8144
                     /gene="rpsH"
                     /locus_tag="ACOIAP_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003241998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGZ2639483.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            8175..8717
                     /gene="rplF"
                     /locus_tag="ACOIAP_002603"
     CDS             8175..8717
                     /gene="rplF"
                     /locus_tag="ACOIAP_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGZ2639484.1"
                     /translation="MSRIGVKPIIVPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8753..9121
                     /gene="rplR"
                     /locus_tag="ACOIAP_002604"
     CDS             8753..9121
                     /gene="rplR"
                     /locus_tag="ACOIAP_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGZ2639485.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            9142..9651
                     /gene="rpsE"
                     /locus_tag="ACOIAP_002605"
     CDS             9142..9651
                     /gene="rpsE"
                     /locus_tag="ACOIAP_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGZ2639486.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9666..9851
                     /gene="rpmD"
                     /locus_tag="ACOIAP_002606"
     CDS             9666..9851
                     /gene="rpmD"
                     /locus_tag="ACOIAP_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGZ2639487.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9884..10327
                     /gene="rplO"
                     /locus_tag="ACOIAP_002607"
     CDS             9884..10327
                     /gene="rplO"
                     /locus_tag="ACOIAP_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGZ2639488.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10371..11639
                     /gene="secY"
                     /locus_tag="ACOIAP_002608"
     CDS             10371..11639
                     /gene="secY"
                     /locus_tag="ACOIAP_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGZ2639489.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGQVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11656..12306
                     /locus_tag="ACOIAP_002609"
     CDS             11656..12306
                     /locus_tag="ACOIAP_002609"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGZ2639490.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVNYYSKQGIIADIKGDQAIDKVFEDIVTALGSGK"
     gene            12307..13053
                     /gene="map"
                     /locus_tag="ACOIAP_002610"
     CDS             12307..13053
                     /gene="map"
                     /locus_tag="ACOIAP_002610"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HGZ2639491.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            13075..13344
                     /locus_tag="ACOIAP_002611"
     CDS             13075..13344
                     /locus_tag="ACOIAP_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HGZ2639492.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13382..13600
                     /gene="infA"
                     /locus_tag="ACOIAP_002612"
     CDS             13382..13600
                     /gene="infA"
                     /locus_tag="ACOIAP_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017185218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGZ2639493.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13636..13749
                     /gene="rpmJ"
                     /locus_tag="ACOIAP_002613"
     CDS             13636..13749
                     /gene="rpmJ"
                     /locus_tag="ACOIAP_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGZ2639494.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13902..14273
                     /gene="rpsM"
                     /locus_tag="ACOIAP_002614"
     CDS             13902..14273
                     /gene="rpsM"
                     /locus_tag="ACOIAP_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGZ2639495.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14309..14707
                     /gene="rpsK"
                     /locus_tag="ACOIAP_002615"
     CDS             14309..14707
                     /gene="rpsK"
                     /locus_tag="ACOIAP_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020449874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGZ2639496.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14739..15362
                     /gene="rpsD"
                     /locus_tag="ACOIAP_002616"
     CDS             14739..15362
                     /gene="rpsD"
                     /locus_tag="ACOIAP_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGZ2639497.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15440..16387
                     /locus_tag="ACOIAP_002617"
     CDS             15440..16387
                     /locus_tag="ACOIAP_002617"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGZ2639498.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICSPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16408..16749
                     /gene="rplQ"
                     /locus_tag="ACOIAP_002618"
     CDS             16408..16749
                     /gene="rplQ"
                     /locus_tag="ACOIAP_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGZ2639499.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16869..17702
                     /locus_tag="ACOIAP_002619"
     CDS             16869..17702
                     /locus_tag="ACOIAP_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGZ2639500.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDGMNTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISGDILTVDEMVMELCR
                     L"
     gene            17690..18556
                     /locus_tag="ACOIAP_002620"
     CDS             17690..18556
                     /locus_tag="ACOIAP_002620"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGZ2639501.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDISFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEEFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKSLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFIGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18550..19353
                     /locus_tag="ACOIAP_002621"
     CDS             18550..19353
                     /locus_tag="ACOIAP_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGZ2639502.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMISIFVVNKFWP
                     YIVVLLCLLAMIKLANIPIKYIVKGVKPLKWIILFTFFINIFFLPGDEIWSFGFLTIT
                     SQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19386..20117
                     /gene="truA"
                     /locus_tag="ACOIAP_002622"
     CDS             19386..20117
                     /gene="truA"
                     /locus_tag="ACOIAP_002622"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGZ2639503.1"
                     /translation="MRNIKITIQYNGKNYCGWQKQLDSLGIQGTIERAIYDITKEKVS
                     LIGSGRTDSGVHAIGQIANFKTNSSISIESIPMALNAKLPKDISVIDACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKLLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDIIRKDDLITFEISGNGFLYNMVRIIVGTLVDIGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            20237..20668
                     /gene="rplM"
                     /locus_tag="ACOIAP_002623"
     CDS             20237..20668
                     /gene="rplM"
                     /locus_tag="ACOIAP_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGZ2639504.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20697..21089
                     /gene="rpsI"
                     /locus_tag="ACOIAP_002624"
     CDS             20697..21089
                     /gene="rpsI"
                     /locus_tag="ACOIAP_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGZ2639505.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21598..22302
                     /gene="cwlD"
                     /locus_tag="ACOIAP_002625"
     CDS             21598..22302
                     /gene="cwlD"
                     /locus_tag="ACOIAP_002625"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HGZ2639506.1"
                     /translation="MRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTII
                     LDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEEN
                     NKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKELS
                     KCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKESKLLTDETYQ
                     EKIAWAIYIGIQKYLS"
BASE COUNT         9048 a         2635 c         4642 g         6195 t
ORIGIN      
        1 gacgtattct caatcacagg aagaggaaca gttgcaacag gaagagtgga aagaggagta
       61 ttaaaagtac aagacgaagt agaattagta ggattaacag aagcaccaag aaaagtagta
      121 gtaacaggag tagagatgtt cagaaaatta ttagaccaag cacaagcagg ggataatata
      181 ggagcattat taagaggagt acaaagaaac gagatagaaa gaggacaagt actagcaaag
      241 actggatcag taaaggcaca cacaaagttt acagcagaag tatatgtact taaaaaagaa
      301 gaaggtggaa gacatacacc attctttgat ggatatagac cacaatttta cttcagaaca
      361 acagacgtaa caggagcttg taagttacca gaaggaatag agatggtaat gcctggagat
      421 aacgtaacaa tggaagtaga cttaataaac tcaatagttg tagaagaggg attaagattc
      481 tcaataagag aaggtggaag aacagtagct tcaggagttg ttgctacaat aatagagtaa
      541 tcctttacta gctaatggat tcaatataaa aaagaggggg taacacctct cttttttgtt
      601 ttttattgac aagtagctct aaagcatata tactaaacta gtgccttgag atagattaac
      661 aatcaattta aggttatgat gttgtaatag aaaataaaat tgaaaaaaag ataaaaaaaa
      721 cttgaaaaaa tgtaacagat gatataaaat ataatagtgt gcttgagaga ttaagaaaat
      781 aagaattaaa tcctagtgaa atacgaactg atatcgattt gaaagttaca acacacccgg
      841 agcagtgtat cggtattggt tgtacgcagc ttgaaaatta aacacgtgat aaaggaggga
      901 aaacaaaatg gctaagaatg aaaaaataag aataagatta aaatcatatg atcacaaatt
      961 attagatttt tcagcaggta aaatagttga aactgctaaa aaggctggat cacaagtttc
     1021 aggacctgtg cctctaccaa cagaaaaaca agttgtaact atattaagag ctgtacataa
     1081 gtacaaagac tctagagaac aatttgaaat aagaactcat aaaagactaa tcgacatagc
     1141 taatccaaca cctaagacag ttgactcatt aatgagatta gacttaccag caggtgtaga
     1201 tatagaaata aaattataag aacccctaag atattatcct atagatgatt atcttagaat
     1261 gattactcta aaagatgtaa tccgctgtaa gaattatagg aggtgctaat atgaaaggaa
     1321 tattaggcaa aaaagttggt atgactcaaa tattcactga taaaggtgta gttatacctg
     1381 taacagctgt tgaagcagga cctatggtcg ttactcaaat aaaaacagtt gataaagatg
     1441 gatacaatgc tatacaaata ggttttgaag atgctaaaga aaaagcttta aacaaaccta
     1501 aaaaaggaca tttagctgct gctaatgttt taaagaaaca tttaaaagaa tttagagtag
     1561 attctgtaga aggatacaca gtaggacaag aaataaaagc tgatgtattt gaagcaggtg
     1621 caaaaataga tgttactgga ataagtaaag gtaagggatt ccaaggtcca ataaaaagac
     1681 atggacaaag tagaggtcct gaaactcacg gttctagata ccacagaaga ccaggttcaa
     1741 tgggagcttg ttcttaccca ggtagagtat ttaaaaacaa aaaattagct ggacacatgg
     1801 gaagcgtaaa ggtaacagtt caaaacttag aggttgttaa ggtagatgct gataagaacc
     1861 ttatattagt taaaggagct ataccaggag ctaaaggttc agtagtaact ataaaagaag
     1921 ctataaaggt ttctaaataa tgactaacct agagaaagga ggaataacaa tgccaaaatt
     1981 aaatgtacta aatgttagtg gacaaaacgt tggagaaata gaattatcag attctatatt
     2041 tggcgtagaa gttaatggac atgttttata tgaagttgta aaaaatcaat tagcaaataa
     2101 gagacaagga actcaatctg ctaaaactag agcagaagtt agaggtggcg gaagaaaacc
     2161 ttggaaacaa aaaggaacag gtagagcaag acaaggttct acaagatctg tacaatgggt
     2221 aggtggagga gttgcttttg cacctaaacc aagaagttac aaatatacat tacctaagaa
     2281 agtaagaaga ttagctatga agagtgcttt atcttcaaaa gttcaaaata gtgaagttat
     2341 agtattagat gcattaaaca tggatgctcc taagactaaa gaatttgctc aaatattaaa
     2401 caatataaat gctgctaaaa aagctttagt agttatagct gacaaaaacg ataacataat
     2461 aaaatcagct agaaatatag aaggtgttca aactgcatta gttaatacta tgaatgtata
     2521 tgatatatta aaatatgatt catttataat aactacagat gctgttaaaa aagtggagga
     2581 ggtgtacgca taatgactaa tccacatgat gtaataataa gaccagttgt aactgagcac
     2641 agtatggctg aaatgggtga aaaaaaatac acttttgttg tggctaaaga tgcgaacaaa
     2701 actgaaataa aaaaagcagt agaaaaagta ttcggagtta gtgttgataa agtaaatact
     2761 ttaaactacg atggaaaagt taaaagaatg ggtagaactc aaggaagaac agcaagcttt
     2821 aagaaagcag tagttaaatt aactgctgat agtaaagaaa tagaattctt ccaaggaatg
     2881 tagtattata acaaacgaag gagggaaaac agatggctat aaaaaagttt agaccaactt
     2941 ctcctgcctt aagacaaatg acagttttag tttctgatga aataacatgc aatcaaccag
     3001 agaaatctct tttagttaac ttaaagaaaa atgctggtag aaacgtacat ggtagaataa
     3061 ctgttcgtca tagaggtgga ggacaaaaaa gaaaatatag aataatagat tttaaaagag
     3121 ataaagatgg tatacctgct aaggttgcta ctatagaata tgatccaaac agaactgcaa
     3181 atatcgcatt attaaactat gctgatggag aaaaaagata tatattagct ccagttggaa
     3241 ttaacgttgg agatactata ttatcaggat taggtgctga tataaaacca ggaaactgtt
     3301 tagcattaaa agatatgcca gttggtacta tcattcataa tatagaatta aagccaggaa
     3361 aaggagctca attagttaga tctgctggag tttctgcaca attaatggct aaagaaggaa
     3421 aaaatgcttt attaagatta ccatcaggtg agatgagatt agtaagcata aactgtaaag
     3481 ctactatagg tcaagttgga aatatagagc atggtaacgt agttatcggt aaagcaggta
     3541 gaaaaagaca tatgggaata agacctactg taagaggttc tgtaatgaac cctaatgacc
     3601 atccacacgg tggaggggaa ggtagatctc caataggtag accatctcct gttactccat
     3661 ggggtaaacc agctcttgga tacaaaacta gaaagaaaaa taaagcttca aataaactaa
     3721 tagtatcaag aagaactaag tagtaaattt atttttgctc ggaaaggagg aatataaatg
     3781 tcaagatcaa ctaaaaaagg gccttttgtc catgcaagac ttttaaagaa gatagaagct
     3841 atgaatgcta gtggaaataa agaagttata aaaacttggt caagatcttc aactgtattt
     3901 ccacaaatgg tagaaaatac tatagctgtt catgatggaa gaaaacatgt tccagtatat
     3961 ataacagaag atatggttgg acataaatta ggtgagttcg ttcctactag aactttcaaa
     4021 ggacataagg atgacgaaaa atctaataag agaaaataat taaattatga ctaagaaagg
     4081 aggaataaca atggaagcaa aagctactgc taaatacgta cgtgtatcac caagaaaagc
     4141 aggccaaata tgtgaccttg ttagaggaaa gaatgttgat gaagcattag caatattaaa
     4201 gtttactcca agaggagcag cttcaataat agctaaagtt gtaaaatcag ctaaagctaa
     4261 cgcagaaaac aatcacgaaa tggatactga aaaattatat atagcatcaa tagttgctaa
     4321 tcaaggacca acaatgaaga gatttatgcc tagagctatg ggtcgtgcaa ctacaataag
     4381 aaaaagaact tctcatatag aggttgttgt taaagagaaa aaataattaa tagataggag
     4441 ggaaagttaa tgggtcaaaa ggttaatcca cacggcttaa gggtcggtgt tataaaagat
     4501 tgggactcaa gatggttcgc tactgataaa aaagagttcg gaaacttatt attagaagac
     4561 cataatatac gtaaattctt aaagaaaaga ttatactcag ctggagttgc taagatagaa
     4621 atagaaagat cagctaacaa aataaaaatg gacttacatg ttgctaagcc tggtgtagtt
     4681 ataggaagag ctggtgcagg aatcgaagca ttaaaagctg aattagaaaa aatgacaaag
     4741 aaaactataa tagttaatat agtagaagta agaagtacag ataaaaatgc tcaattagta
     4801 gctgaaaata tagctttagc tatagagaga agggttgctt tcagaagagc aatgaaacaa
     4861 gctatacaaa gagcaatgaa atctggtgct aaagggataa aagtttctgc ttcaggaaga
     4921 ttaggtggag ctgaaatggc tagaactgaa ggttatagtg aaggaaatgt gccactacaa
     4981 actttaagag cagatataga ttatggtttc gctgaagctg atacaactta tggaaaaatc
     5041 ggtataaaag tttggatatg taatggtgaa gttttaccaa ctagagacgg tgtaaatcca
     5101 agagaagaaa gcagaaagag cgatagaaga gacaacaaga gagataatag aagaaacgat
     5161 agaagaggaa atgacagaag aggaaatgat aacagaggaa actacagagg acaaagacct
     5221 caaggtggat caagacctca aagaactgaa aacaaaggaa attaataata gttaggttca
     5281 aggaaggagg aaaaatactc atgttaatgc caaaaagagt aaagcgtcgt agagttcata
     5341 gaggaagcat ggctgggcaa gctcataagg gtaataaagt tacttatggt gagtttggat
     5401 tagtagcatt agaagcttct tggataactt ctaatcaaat agaagctgcc agaatcgcga
     5461 tgactagata tataaaaaga gggggaaagg tttggataaa aatattccct cataaaccag
     5521 taacaagaaa accagcagag actcgtatgg gtgcagggaa aggttctcca gaatattggg
     5581 tagctgtagt taaaccagga agagttatgt ttgaattagc aggtgtttct gaagataaag
     5641 caagagaagc tatgagactt gctgcacata aattaccaat caaatgtaaa tttgttaaaa
     5701 aagaagattt agaagtaaag ggtggtgaat aggatgaaag ctaaagaatt aagagattta
     5761 acaagcgaag agctaatgaa caaattaaac gacttcaaaa gtgaattatt tagcttaaga
     5821 ttccaattag ctactggtca attagaaaat acagctagaa taaagtttgt taagaaggat
     5881 atagcaaaag ttaaaactgt tcttgctgaa agaaagttat acgaaactag agcttaattt
     5941 ggaaaggagg ctttttaaac atggaaagag gaagaagaaa agttagaata ggccgtgttg
     6001 ttagtgataa gatggataaa acaatagtag tagctgttga agaattcgta cgtcatccac
     6061 tatataataa acgtgttaag agaactaaga aattcaaggc tcatgatgaa aagaatatat
     6121 gtaacatcgg agatagagtt aaaataatgg aaactagacc attatctaaa gataagagat
     6181 tcagactagt tgaagttgtt gagaaagtta agtagttttt gaagaaggag ggattacgat
     6241 atgatacaac aagaatcacg tctaagagtt gctgataact caggagctaa agaactttta
     6301 tgtatacgtg ttctaggcgg aagtaaaaga agatatggta acataggcga cgttatagtt
     6361 gctactgtta aaagtgcaac acctggtgga gttgtaaaaa aaggtaaggt tgttaaagct
     6421 gttatagtaa gaagcaaaca aggcgtaaga cgtaatgacg gaagctatat atcttttgat
     6481 gaaaatgctg ctgttataat aaaggacgat aaaactccag taggaactcg tatattcggg
     6541 cctgttgcta gagagttaag agacaatgaa ttcatgaaaa tagtttctct tgctccagaa
     6601 gtactataat taaggaggtg caataggaca tgatgcgtgt taaaaaaggt gacactgttg
     6661 tagttatagc aggtaaagat aaaggtaaaa aaggttcagt tttaaaggta tatcctaaaa
     6721 ctagcaaagt gttagttgaa ggtgtaaatg taataactaa acatcaaaaa ccaagtgcta
     6781 tgaaccaaca aggtggaata ataaataaag aagccccaat acacatatct aatgtaatgc
     6841 catttgatcc tgaaacagga aaaggcgtta gagtaagata tgaagtaaaa gatgggaaca
     6901 aagtaagagt atcagcaaag agcggaaaag aattataata aatattgctt gaaaggaggg
     6961 accttaaatg gcttctagat tacaagaaaa atacatgaaa gaagttgctc ctgctttaat
     7021 ggagaaattt ggatacaaaa acgtaatgga gatacctaag ttaaataaaa tagttattaa
     7081 catgggtata ggtgacgcta gagaaaatcc aaaaggatta gaaaaaggcg ttgaagaatt
     7141 agaaataata tcaggacaaa agcctgttat aactaaagct agaaaatctg ttgctaactt
     7201 caaattaaga gaaggaatgc caataggaac aaaagttaca ttaagagctg ataaaatgtt
     7261 ctactttatg gacaaattag tttcagtttc tttaccaaga gttagagact ttagaggagt
     7321 taaccctaat gcttttgatg gtagaggaaa ttatgcttta ggagttaaag aacaattaat
     7381 attccctgaa atagaatatg ataaaataga taaagtaaga ggaatggata taatatttgt
     7441 tactacagca aagactgacg aagaagctcg tgaattatta aaattattag gaatgccatt
     7501 ttctaagtaa gcaaaggagg gattcccgtg gctagaaaag cgatggttgt taaacaacaa
     7561 agaaagcaaa agtacgctac tagagaatac actagatgta ctatatgcgg aagaccgcat
     7621 tcagttttga aaaaatttgg tatatgccgt atatgcttta gagaattagc ttataaaggt
     7681 caaatacctg gtgttagaaa agcaagctgg tagaagcttg attagaatgg aaggagggca
     7741 acaaaatgac aatgacagat ccaattgcag atatgcttac tcgtataaga aatgctaatg
     7801 ttgttaagca tgaaactgta gatgttccag cttctaatat gaagaaagaa ttagctagaa
     7861 tcttattaga agaaggtttc ataagaggtt atgatgttat agaagatgga aaacaaggta
     7921 tcataagaat acaattaaag tacggacaag aaggcgaaag agttataaca ggtcttaaga
     7981 aaatatctaa gcctggaatg agagtttacg ctgctaacca tgagatacca aaagtattaa
     8041 acggattagg aatatcagtt atatctactt caaaaggaat attaactgac aagcaagcta
     8101 gaaaagaaaa tgttggtgga gaagtaatct gctacgtttg gtaatcaata tgaacaatgt
     8161 aaggaggtgc gaccatgtca agaataggtg ttaagccaat aatagtacca gcaggtgttg
     8221 aagttactat agctgaagga aatttagtta cagtaaaagg tccaaaagga actttaacta
     8281 aacaattaag tgctgagtta aacataaaaa aagaagaaaa tacaataatg gttgaaagac
     8341 caactgataa taaaaaacat agatctttac acggactaac tagaacttta ttagataata
     8401 tggttgtagg tgtaaatact ggtttcgaaa agaaattaga attaaaaggt gttggatata
     8461 gagctcaaaa acaaggaaag aaattagtta tgaacttagg tttctctcat ccagttgaga
     8521 tggaagatcc agaaggaata actgttgaag ctccaaacca aacagagtta atagtaaaag
     8581 gtatagacaa gcaattagta gggaactatg ctgctaagat aagagcttgg agaaagccag
     8641 agccatacaa aggtaaaggt ataaaatacg ttgatgaagt aatcagacgt aaagaaggaa
     8701 aaactggtaa aaaataatac caaaacttaa acgctagaaa ggagtgagct aggtgttaaa
     8761 aaaggctgat aaaaatgcta atagacttca aagacataag agagttcgta gaaaaataag
     8821 cggtacttct caaagaccaa gattatgtgt atttagaagt gctaacaata tatatgctca
     8881 aataatagat gacacaaaaa gagtaactct agttgctgca tcttctttag aagcagaagt
     8941 taagagtgct gtcaatcata caggaaacaa ggaagcagct aaaaaagttg gagaattagt
     9001 tgctaaaaaa gctgttgaaa aaggaatcac tgaagttgta tttgacagag gtggatactt
     9061 atatcatgga agaattcaag aattagctga aggtgctaga gaagctggtc ttaagttcta
     9121 atacgaagga gggaaaaata catgctacgt cgtaagccga tagatgcagg acaacttgac
     9181 ttacaagaaa aagttgttga agtaagacgt gttactaagg ttgtaaaagg tggtagaaac
     9241 ttcagatttg cagcattagt agttgttgga gatgaaaacg gacacgttgg tataggtgct
     9301 gggaaagcaa tggaagtacc agacgctata aaaaaagcag ttgaagatgc taagaaaaat
     9361 ctaatagtag tgccaatagt tgggactaca attcctcacg aagtacgcgg acactttggt
     9421 gctggaaata tattaataat gcctgctgtg gaaggtacag gagtaatagc tgggggacct
     9481 gctagagccg tacttgagct agctggacta aaagacgtta gagctaaatc tttagggtct
     9541 aacaatccaa gaaatatggt aaatgctaca atagaaggac ttaattctct aaaaacagtt
     9601 gaagatatag ctaaacttag aggtaaaaaa gttgaagaac ttctagggta aggaggtagt
     9661 gtaaaatggc taaattacaa ataaagttag ttagaagtgt tataggaact actcctaacc
     9721 aaaaaaagaa tgttgaagcg ttaggattaa gaaaaagaga acaagttgtt gtaaaagaag
     9781 acaatgctca aacaagaggt atgataaata aagtaagtca cttattagaa gtaactgaaa
     9841 tagctgaata atttttataa agtagtgcaa ggaggtgcaa tccatgaagt tacatgagtt
     9901 aaaacctgct gaaggtgcag taagagctaa gagaagatta ggtagaggta ctgcaactgg
     9961 acaaggtaaa actgcaggac gtggacaaaa aggtcaatgg tctcgttctg gtggtggagt
    10021 aagagtagga tttgaaggtg gacaaatgcc actagctaga agacttccta agagaggttt
    10081 caataacata tttaagaaag tttacacaga agttaatgtt gaagttttaa acagatttga
    10141 aaatggaaca gaaataactg cagaattatt aaaatctact aaaactataa gcaaaatagg
    10201 taaagatgga attaaaatct taggtgaagg taatttagag aaagctttaa ctgttaaagc
    10261 tgctaaattt acagcttcag ctcaagaaaa aatagaaaaa gctggtggaa aagcagagtt
    10321 agtataataa cctgctaatc tcctagccag tacaggcggg gtgaattagc gtgctgtcaa
    10381 aattaaaaca agcttggaag attaaagcag taagaaaaaa agtaatgtat acacttatga
    10441 tgatcgtgat attcagaata ggtactacta taccagttcc aggcatagac actagtatta
    10501 tacaaaagat ggtaggcggc aatagtctac tttctctgta taatatgttt actggtggag
    10561 cttttagtaa tttttcacta tttgctttag gtataagtcc atatatcact gcatcaatca
    10621 taatacaact tctaacagta ggttttgaaa gtttagcaga acttcaaaaa tctggtgaag
    10681 aaggaaagaa aaaaatcaat aagtacacta aatatacagc actagctcta gcagttgtac
    10741 aagctttggg aattacatta ggaattgtaa gaagtgcttt aatatcaaat agtgtgtttt
    10801 ttatcacaac tgttgtaata acattagttt cagcaagtat gttagtaatg tggattgggg
    10861 acaaaattac tgaaaaagga ataggtaatg gtagttcagt aataatattt gcaggtataa
    10921 tatcaagaat acctacagac gttattaaaa tctcgcaaca agttaaatct ggccaagttg
    10981 caccttgggt tatagtaatt ctagccgtag ttatattact tacagtaaca ggagttacat
    11041 ttatacaaga agcaactaga aagatacctg tacaatatgc taaaagagtt gttggaagaa
    11101 aaatgtatgg cggacagagt tctcatatac caatgaaagt taaccagtca ggagttatgc
    11161 ctataatttt tgctagttca cttttagctt tccctcaaac aatagctatg tttatgggtc
    11221 caaatgctca ggcttttgtt caaaaatact taagtatggc aacagaacaa ggattttgga
    11281 catatagatc aattgagatt ctacttataa ttttcttctc atatttttat acgactgtat
    11341 catttaatac agaagacata tctaaaaata tgaagaataa tggtggattt ataccaggta
    11401 taagaccagg tgaacctact atggattatt taaatagaat tttaactaga ttaactttag
    11461 ctggagctac tttcttagca ataattgcta tggtgccagc tcttacaaca cattatatga
    11521 aagtaaatat gagtctagct gggacttcat tgctaatcgt tgttggagtt gctttggagc
    11581 ttaagagaca gttagagtca aacttagtta tgagaagcta tcaaggtttc ttaaaataaa
    11641 atggagatgg ataatatgag aataatatta cttggacctc caggtgctgg taaaggtact
    11701 caggcggcag gaatagtaga aaaatacaat atacctcata tatcaacagg agatatattc
    11761 agaaagaata taaaagaggg aacagaactt ggaaaaaaag ctaaagaata catggaccaa
    11821 ggtttattag taccagatga gttaactgta ggtttagtta ctgatagaat atctcaagaa
    11881 gattgtaaaa atggatttat gttagatgga tttccaagaa atgtagcaca aggagaacat
    11941 ttagatatct tcttaaaaaa tgctggtata tcactagata aagttgtcaa tattgaagtt
    12001 gataagagta tactagtgtc tagagcagtt ggtagaagaa tatgtaagtc ttgtggagct
    12061 acttaccatg ttgagtttaa tcctcctaaa gtagaaggtg tatgtgatgt atgccaagga
    12121 gaattatatc aaagagctga tgataatgaa gaaactgtat ctaagagaat acaagtttat
    12181 ctagatgaaa ctaagcctct agtaaactat tatagcaagc aaggtataat agcagatata
    12241 aaaggtgatc aagcaataga taaagtattt gaagatattg tcacagcctt aggaagtgga
    12301 aaataaatga ttatcttgaa atcaaaaaaa gaaatagaac ttttaagaga agcaggcaaa
    12361 atagttgctg acactcatga agttttaaga aaagctattt ctccgggaat atctacttta
    12421 gaattagata aaatagctga agagaatata agaaaataca atgcagaacc ttcttttaaa
    12481 ggatatggag gttttccagg aagtatatgt gcttctatca atagagaggt agtacatggt
    12541 attccaggag aaactatatt acaagaaggg gacattgtaa gtttggatat aggagcctat
    12601 tataaaggat atcatggtga ttctgcgaaa actcatggag taggcatgat atctgaagaa
    12661 gataggaaat tgatagaagt aactagagaa agcttctatg aaggaataaa atttgctaaa
    12721 ttaggatata gactttcaga tatctcacac gcagtacaaa cacacgttga gaaacatggt
    12781 ttctcggtag ttagagattt agtgggtcat ggagttggag caaatcttca tgaggaccca
    12841 caagtaccta actatggact cccaggaaaa ggaccaagac ttagagaagg aatggttatt
    12901 gctatagagc caatggttaa tgcaggtcgt tatcatgtaa agactctatc agatgggtgg
    12961 acgactgtta caatagatgg aaaaaaatca gctcattatg agcatacgat agcaattact
    13021 gaacatgaac ctttgatatt gacaaagttg taatttaaaa agtaggtgaa aaaagtgcta
    13081 tcagataatt taagtatagg tcaagttgtt aaagtttcat taggacgaga taaaggaaat
    13141 ttattctttg tagtcaaaat aattaataat gaatatgtat taatagctga tggaaaaaag
    13201 agaaaacttg acaaacctaa gttaaagaaa gtgaagcact taaaaaaata taattttatt
    13261 aatgatgaag ttagaaaaag agtagtatct ggacaagaga ttacagattc ttttttaaga
    13321 gctgaactta ctaagttaaa ttagataatt taacttattg aaatggaggg ctggttagtt
    13381 aatggccaaa aaagatgtta tagaattaga aggtacagtt tcagaagctt tacctaatgc
    13441 tatgttcaaa gttaaactag aaaatggaca tgagatatta tgccacattt ctggaaagct
    13501 aagaatgaac ttcataagaa ttcttgaagg tgataaggtg aatgttgaac tttctccgta
    13561 tgaccttaca agaggaagaa ttacttggcg taagaagtag actatattaa tatttagtct
    13621 aaggagggat taataatgaa ggttagacca tcagtaaaac caatatgtga aaaatgtaaa
    13681 gtaataaaaa gaaaaggaaa agtaatggtt atctgtgaaa atccaaagca taagcaaaag
    13741 caaggataag aaattattac tagcattttg ttaaatttta tagtataata ctatattgtg
    13801 atgttaacaa aagaacgtta aaatcgttga acaatctggc gtaggattgg catatgatgt
    13861 gaagttttaa acactaaaaa ctatgtgtag gaggtgcgat catggcaaga atagctgggg
    13921 tagatttacc tagagaaaaa agagcggaga taggcttaac ttatatatat ggtataggta
    13981 aagcgactgc taacgaaata ttagctaagg ctgagataaa tccagatact agaataaaag
    14041 atttatcaga agatcaagtt aatgagttaa gaaaagttat agatgacgat ttcttagttg
    14101 aaggtgactt aagaagagaa attgctttaa acataaagag attaagagat atcaaatgtt
    14161 atagaggaat aagacacgct aaaggtcttc cattaagagg acaaagaact aagactaatg
    14221 ctagaactag aaaaggtcct agaaaaacag tatctcgtaa aaagaaaaaa taaataaata
    14281 ataactagat gaaggaggga aaaggaaaat ggctaaacca aaaaagaaag ttacacgtat
    14341 tagaagaaga gaacgtaaaa atatagaacg tggtcatgct catatacaat caactttcaa
    14401 taatacaata ataactttaa ctgacgttca cggaaatgct atatcttggg caagttctgg
    14461 acaattagga ttcaaaggat caagaaaatc aactccattt gcatctcaaa tggctgctga
    14521 aacagctgca aaagctgcga tggaacacgg actaaaaagt gttgaggtat tcgtaaaggg
    14581 gccaggttca ggaagagaag ctgcaataag agctttacaa gcaactggac tagaagtaac
    14641 tatgataaaa gatgttactc caatcccaca taacggatgc agaccaccaa agagaagaag
    14701 agtgtaatta ataagagtac aataggaggt gtagataaat ggcaagatat acaggtgcat
    14761 catgtagaca atgccgtaga gagggaatga aattattcct taaaggtgat agatgttata
    14821 cagataaatg tgctatagta aaaagaaact atgctccagg tcaacatggc caaggaagaa
    14881 agaaagtttc taactatgga ttacaattaa gagaaaaaca aaaagttaaa agaatatatg
    14941 gagttttaga gactcaattt agaaatttat atgaacgtgc tgaaaatatg cctggtaaag
    15001 caggtgagaa cttattaagt ttattagaga gaagattaga taatgtagtt tacagaatgg
    15061 gactagcatc ttctagaaaa gaagctagac aattagtgac tcatggtcat ttcactttaa
    15121 atggaaataa agtagacata ccttcattaa tagttaaggt tggagatgtt atagaagtta
    15181 aagagaaatc aagatcttct gcaaaattca aaaatttagt agaagttaac tcaagaatag
    15241 ctcctaagtg gttagaagct aatgtagaag gaatgacagc aaaagtagtt ggtgttccaa
    15301 caagagaaga tatagatctt gagatagcag agcacttaat catagaactt tactctaaat
    15361 aataagcaca cttttaaaaa ttattttaaa attttgttta ccctcagtgg attactgaat
    15421 tttaaggagg gttttgtcca tgatagaaat agaaaagcca aaagtagata tagttgagct
    15481 tagcgaagac tatagatatg gtaaatttgt tatagagcct ctagaaagag gatatggaat
    15541 aactataggt aacgcattaa gaagaatatt attatcatca ctaccaggtg tagcagtgaa
    15601 cgctataaaa atagatggag ttcttcatga attttcaaca atacctggtg tcaaagaaga
    15661 tgttactgag ataatattga ctttaaaaga gctttcagca actatagatg gtgaaggaag
    15721 tagaacactt aaaatagaag ctcaaggacc atgctctatc acaggtgcag atataatctg
    15781 ttctccagat gtagaaatat taagtaaaga tttagcaata gctacattag atgataatgc
    15841 taagcttaat atggagatat ttgtagataa aggtagaggt tatgtttctg ctgaagaaaa
    15901 taaaacagag aatgttccaa taggtgtttt acctgtggat tcaatatata ctcctgttga
    15961 gaaggttagt tatcatgtgg aaaacacaag agttggtcaa aaaacagatt atgataaatt
    16021 agtactagaa gtttggacta atggtagtat aaatcctcaa gagggtatat cattagctgc
    16081 aaaggtacta gttgagcatt taaacttatt tatagactta actgaacatg taagtagtgt
    16141 tgaaatcatg gtagaaaaag aagaagatca aaaagaaaaa gttcttgaaa tgactataga
    16201 agaattagat ttatcagtta gatcatataa ctgtttaaag agagcgggaa ttaatacagt
    16261 tgaagaatta gctaataaat ctgaggatga tatgatgaag gttagaaacc taggtaagaa
    16321 gtcattagaa gaggtaatac aaaaactaga agaacttgga ttgggattaa aaccaagtga
    16381 agaatagcga gcaaaggagg gataagaatg gctaagtacc gtaaattagg acgtgaaaca
    16441 gctcacagaa accttatgtt aagaaactta gtaacttgtt tactaagaag tggaagaata
    16501 gaaactacag tgactagagc gaaagaaact cgtagaatgg ctgaaaagat gataactctt
    16561 gctaagagag gagatcttca tgctagaaga caagttttag cttatgttat ggatgaaaca
    16621 gtagttaata acttattcac agatttagct ccaaaatatg ctgagagaaa tggtggatac
    16681 actagaataa taaaaatagg gccaagaaaa ggcgatgctg ctgaaatggc ttttatagaa
    16741 ttagtatagt aaggaaagga ttaggcttga tggcttaatc ttttttttat ttttttgact
    16801 aaggtatgat ataataatgt gtaaaatgat ttttataagt tattgcttac taaaaggagt
    16861 atgaattaat ggataatata gtaaaggtaa ataatatttc gtttgagtat attacagatg
    16921 aagcaaaact taaagcaata gataatttaa gcctagatgt taaaaaggga gaatttgttg
    16981 cgataatagg acataatggt tctggtaagt ctactttatc taaaaactta aatgctattc
    17041 ttatgcctac tgaaggaaat attcttattg atggtatgaa tactaaagaa gaagaaagat
    17101 tatgggatat aagacaaact gcaggcatgg tatttcaaaa tccagacaat caaatagttg
    17161 ctactatagt agaagaagat gttgcatttg gacctgagaa cttaggtata gaaccaaaag
    17221 aaataagacg aattgtagag gagtctttaa aaagtgtagg tatgtatgat ttaagagata
    17281 gacagcctca cttgttatca ggaggtcaaa agcaaagagt tgcaatagca ggaattattg
    17341 ctatgaggcc taaatgtata atatttgatg aagcaacagc aatgttagat ccatctggaa
    17401 gaaaagaagt tatgaaaaca ataaaaagac ttaataagga agaaaatata actgttatac
    17461 atataacaca ctttatggaa gaagcagtag aagctgatag agttgtagtt atggaaaaag
    17521 gtaagaaaat cttagaggga actcctagag aagtatttag taaaataaag atgttaaagg
    17581 aaatcggttt agatgtccct tgtatgacag agttatctag tttattaata gaagaaggta
    17641 taaatattag tggtgatata ttaactgtgg atgagatggt gatggaatta tgtcgattat
    17701 agtaaagaac ttaacacata tatataatga agggatgcct tttgcaagta aggcacttga
    17761 tgatatttct tttgagatta aagatagaga ttttgttggt ctcataggtc atacaggctc
    17821 aggaaaatct acattaatac aacatttaaa tggattacta aagccttcct caggagaaat
    17881 atttataaat gattttaata taacagataa aaacttgaat ttaactgaga ttagaaaaag
    17941 agtaggggtc gtatttcaat atccagaata tcaattgttt gaagaaacga ttgataaaga
    18001 tatagccttt ggaccctcta atttgggctt agaggagtcc gagatacata atagggtaaa
    18061 agcatcgatg gaagctgtag gacttgatta tgaggaattt aaagataaat ctccttttga
    18121 attatctgga ggacaaaagc gtagagtagc aattgctgga gttatagcca tgaacccaga
    18181 agttctcata ttggatgaac caactgctgg tcttgaccct ggtggaagag atgaaatttt
    18241 taacttaata aaaagcttac atgaaaaaaa gaatatgact ataatactat catcacatag
    18301 tatggatgat atggcaaaat tagcaaaaac tttaattgtt atgaatcatg gtagtgtaga
    18361 atttatagga actcctagag aagtatttaa atcaaacgct agtaaattaa aagatatagg
    18421 attagatatt ccacaagttt tagagcttgc attgaaattg agagaaaaag gctttgacat
    18481 cagtgaggat atcttgactt tagaagaagc caaacaggaa atattaaaag ttgtgagagg
    18541 acgaggatta tgttaaaaga tataactata gggcaatact acccaacaag ttctgctatt
    18601 cataaattag atccaagaat aaagcttgta gcaacaattg tatttatgat atctatattt
    18661 gtagtaaata aattttggcc ttatatagta gttttattat gtttattagc tatgataaaa
    18721 ttggctaata taccaatcaa atatattgtt aagggtgtta aacctcttaa gtggattatt
    18781 ttgtttacat tttttataaa tatttttttc ttaccaggtg atgaaatatg gtcatttgga
    18841 tttttaacta ttacaagcca gggtctaaga caagcaattt ttatggcaat aagattaata
    18901 tttttagtag ttggtacatc attgcttact ttaacaactt caccaataga attaactgat
    18961 ggaatagaga gattgttgaa cccatttaag aaaattggtt tgccagttca tgaacttgca
    19021 atgatgatga caattgcttt acgttttatt cctacgttat tagatgagac agataaaata
    19081 atgaaagctc agatgtctag aggtgcagat tttgaaagta agaatcttat aaatagagca
    19141 aagaatttag taccactttt ggtaccttta tttgtgagtg catttagaag ggctgatgaa
    19201 ttggctatgg ccatggaggc cagatgttac agaggtggac ataatagaac taagatgaga
    19261 gagtctgtta tatcaagaag agattatatg gcatgtgtat ttcaggttgt ctatctagga
    19321 gcaattatag ctactagatt tatagcaatt taattaataa gttatagata taaatgaggt
    19381 aaaatatgag aaatataaaa attacaatcc aatacaatgg taagaattat tgtggatggc
    19441 aaaaacaact tgattcttta gggatacagg gtacaattga aagggctata tatgatataa
    19501 caaaagaaaa agtaagtctt atagggtctg ggagaactga ttcaggggtt catgctattg
    19561 gtcagattgc aaactttaaa actaattcaa gtataagtat agaaagtata ccaatggcac
    19621 taaatgccaa gttaccaaaa gacatatcag ttatagatgc atgtgaagta aatgatgatt
    19681 ttcactcaag atatagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19741 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19801 aaatgtgttc agaagcaaaa cttttattag gaacacatga ttttaaaggc tttatgagtt
    19861 ctggctcgtc tgtaaaagat acagttagaa cgatatatga tattgatata attagaaaag
    19921 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19981 ttgttggaac acttgttgat ataggtcgtg gtagaattaa cgaaccattt ttagatataa
    20041 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    20101 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    20161 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    20221 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    20281 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    20341 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    20401 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatactacag
    20461 ataccatact ggttatgtag gtggattaaa agaaatatct tacagagata tgatggataa
    20521 gaaaccagag gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20581 aagtagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20641 aaatccagaa gttttaaact ttaagtaaga ttaataggtg aaaggaggag tttataatgg
    20701 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20761 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaactatg
    20821 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20881 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20941 gtatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    21001 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    21061 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaaa caaaatcctt
    21121 tatttactgc tattcagaaa atattggtat tttaaaaatg ttgggttaag ttaattatta
    21181 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa aagcatcctt
    21241 tttattttga ctatctaata aagaatatat gctaataata tttagatttt atttttataa
    21301 tattgtgatt taaaagttta cataagatga tatattttaa gatattattt aacaatataa
    21361 attatgaata tatcttatca aagtttataa tataaactaa atataattta ttgtatagta
    21421 ttgaatgtta gataaatata gtgagttaaa gaggggtagg gacatagtat cattacataa
    21481 taatgtatta atactaataa atagatatat ataaatatta aaagaaaatt taaatgtttg
    21541 tactaatatt tggaatatta tagtgttttt ataagtatac atatacaggg tgatgttgtg
    21601 agaaagtaca taaaacatat aatttttagt tttgcaatga tatgtctagt agtagtatcc
    21661 atatttgaaa ttaaaaatat ttctgaagat gttatcaagt atatgccagt aacaaacaaa
    21721 actataattc tcgatgctgg tcatggaggt attgatccag gcgcattaaa taaggataag
    21781 agtacatctg aaaaggatat caacctagca ataacactta agcttagaga gcttatagaa
    21841 tcaagtggtg gtcttgtaat attaactcga gaggatgaca gtagccttta taaagaagaa
    21901 aataataaaa ctacaagaca aaaatataat gagaatttga agaatagaaa agaaataata
    21961 tctaattcta atgcaaatat gtttgtctct atacatctta atgcatttga gcaatcaaaa
    22021 tactatggag ctcaaacttt ttatcctaaa gataagcaag atagtaaaga attatcgaag
    22081 tgtattcaag aagaacttaa aagagtggta gataaaacaa acaatagaga agtcaaaccg
    22141 agggatgata tatatctttt gaaagaaaat aatattccat cagtattgat agaatgtggt
    22201 tttttatcaa atgaaaaaga gagtaaactt ttaactgatg aaacatatca agaaaaaata
    22261 gcatgggcaa tttacatagg aatacaaaaa tatttaagtt gaaataacta taaaaatagg
    22321 tctaaatatg taaatagctt gtattaaagc agttaaaatg cattaatata ggctattttt
    22381 attttgacaa aaaaatattt aaaataaaag ttaaaaaata gttgacttag aatggtatag
    22441 atgatattat atatgagtgc ccaaaaggag caccaaaata agacaaaaga actttgaaaa
    22501 ttaaacagta ggttaattta
//
LOCUS       DBGJFK010000058        22391 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.058, whole genome shotgun sequence.
ACCESSION   DBGJFK010000058 DBGJFK010000000
VERSION     DBGJFK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.058"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(342..1373)
                     /locus_tag="ACOIAP_002626"
     CDS             complement(342..1373)
                     /locus_tag="ACOIAP_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639507.1"
                     /translation="MKIEMGESLLYSWLRHVKECQIVQTNWKVSSKWDLKNADKILEI
                     MEKTKQYFEQKYGYPIYKNNSLEQLIMQAEVDVLGISIDNGRNHIYAIDVAFHEAGLN
                     YGSKNETVTRVIKKCIRTAMCIYGYMDLDEAEIIFASPKINPAIITELEPKMAEVNDL
                     FKSLGLRFKTRLIANEEFNGKILEPILIASDGISDTSELFLRSYQMYSMFSYSRDVVK
                     QQRIKKSNSLKDAVELNLSDETLKELKIGKLVQVTMKHLFEEEKISPEEIDKMTQSSY
                     SKQVFNENKPVLKEVPKDGNINELKKDEKNYNRYYAYTISIYGKQYLLVSQWIEDLHR
                     SYYESWVIK"
     gene            complement(1524..2156)
                     /locus_tag="ACOIAP_002627"
     CDS             complement(1524..2156)
                     /locus_tag="ACOIAP_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639508.1"
                     /translation="MTNVSSLEKEDEIVEILSSKENIRVAIEIERGLKLCKTQMIKKV
                     LEEIEKRMDKKFEDKYKLPYYSYKENNYALVNNYYNKKSSTYPAINYFIKSLDKEDVD
                     LLLRIEIDHHIFVGFCTLYKEKPSGKILSDDEIKELINDDGSRTNGWWICWEYIYNNT
                     MECPNFKNFNDAYFDLFDDNKFDEFMDLCEKRILSILGKLKDKQCINTFI"
     gene            2328..2825
                     /locus_tag="ACOIAP_002628"
     CDS             2328..2825
                     /locus_tag="ACOIAP_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HGZ2639509.1"
                     /translation="MFLIIITGLFTITMSVDTLRNQFIKIVIEIYEDLTEFIFSKDIQ
                     TDKNLDFILKEPKYIPNGFKEVEKENTLQGIFIRYENKNGSEIRYRSNQIDSNTVILD
                     TENAKVTDIMVNDYEAKYIVKDNSITIFWNDEENVYTIYFDYDNKNDLNKYKDNLIDI
                     AENIK"
     gene            2900..3322
                     /locus_tag="ACOIAP_002629"
     CDS             2900..3322
                     /locus_tag="ACOIAP_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639510.1"
                     /translation="MYLKKVIVAGLCTLTCLLPLNVQAFEDTSLNTNDYNQTNDNDLF
                     MIYIKGAGSNLSIRSGKAHISCYVDGKIGSLTSITARLQQKKSGKWVTISTWSSSGKT
                     SSTLSREYRVSKGYSYRILTTIKAGNESRNITSNVTNY"
     gene            3352..4038
                     /locus_tag="ACOIAP_002630"
     CDS             3352..4038
                     /locus_tag="ACOIAP_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639511.1"
                     /translation="MKYFKKVIALGLSIALLIPVISINALEKKDTNVNNQIINVIESN
                     VSYTKEGIEVSSDLKNDLKEINLEDIKEQMIEQGIDSKFINNFNSDVIYSLVKENIDD
                     INEGVKNKTLKITPEEDIINNTDNSFYVQGGSTYTQKFSWGVRQNKSTAAANRWVYDL
                     NKSSQGFVATGAVSVLLGSMGAPIGFVSGLSAAYMGGLANKVSYVNSRNNRGITVDIN
                     WWLTYAVKNQ"
     gene            4186..4998
                     /locus_tag="ACOIAP_002631"
     CDS             4186..4998
                     /locus_tag="ACOIAP_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGZ2639512.1"
                     /translation="MNYSDMHEISSGKSQKIALIDSGISKFQKVYKNINLTNSNNDYD
                     TNGHGTMMYSIIKGYNKNNQTIEGISPDSRIILIKVMNDDESINPNVIEDAIDYALNE
                     KVDIISLSLGSTKTDINIKQKIDKANLKNITVVSSAGDYKQGFLLFPASLNNVISVGS
                     IDDRRDISTLTNAPQKTLINAPGEKIKVIDNNNNVFYGKGTSEATAIITGYIALMRDT
                     NISSTQILTNEKIMNLLSQINKNEKTYLGALKEIRKKVSVSTGAFFSFDLSY"
     gene            complement(5943..6299)
                     /locus_tag="ACOIAP_002632"
     CDS             complement(5943..6299)
                     /locus_tag="ACOIAP_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HGZ2639513.1"
                     /translation="MNIIYEKEFTFDNKVREFISLGNNYKFEFSTSKSPKTLIKYFMD
                     YNKISSNKLESFKEKYSFKKNELLSLQEILKNKFTEDDKLESLKLSKANLENELKLGN
                     SIIKKSNSNHNMVEKK"
     gene            complement(6415..6645)
                     /locus_tag="ACOIAP_002633"
     CDS             complement(6415..6645)
                     /locus_tag="ACOIAP_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGZ2639514.1"
                     /translation="MSYAETKACACSDDSILKLCEINREIQIIEINKKAFLNQNLLTL
                     NDIKSTENSIDALKISISKLEEDIKTYFSNFF"
     gene            complement(6818..9031)
                     /locus_tag="ACOIAP_002634"
     CDS             complement(6818..9031)
                     /locus_tag="ACOIAP_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGZ2639515.1"
                     /translation="MNQSYHNIKNELLSKQLAYIDRLTGYLVDRDNYLSGYVKEKLKI
                     AKEASIKDNTFLVNVKALEANQPKYETDVFFSIDSTWISSSIKSDFIEKTLELKENSI
                     QLLYSTQLGYSVKCSDIIPISKNEFTWGTKRRKSLYIVEAELNMKTITVTDKEYQNGK
                     EVSVKNLEETQLAMNILNKWLIAFHNYVTSNSYIHKELLDRYNEMFIDYKEKEYKNIL
                     NDVRINPNIKLREHQLKAASRIITSDRNTLLCHSVGSGKTYTMITAAQELNRISKIDS
                     KKGNKNLFVIPNSLCESGQFAKEYFNLYPQANILATTSKDFSKSNRRKIIAKIVTCNW
                     DSIIIPHSVLGLIPLEADTELKLLDLYLKELNDTLKYYKKECPDLSTKRLETMKENYL
                     NRIKELNDMHKDDALLSFEKLGITNLFIDEAHNFKNLYFNTTMQVPGISTLKTKKTQD
                     LYNKLRYFKSIHGNKGVTFATATPISNSICEMYTLLTYLNKDTLKYYKVDTFNAWASK
                     FGSIISSMEVDPTGQGFRFQQRFAKFCNVPELVNIFRQIADVVNICDINDLDIPQIKG
                     GKPIIEIIKPTNQMKEYIDSLVKRAEKIHEGPYDPIIDNMLNVTTDGRLMAVSPALVG
                     IDGILPKIIKVGENIASLYHEDKISTHLVFCDLGTPNGNSHNVYNDIKNELLKNNVLE
                     KDIAYIHDANTPEKRKKLIDDFNNGIIRILIGSTSKITSSCRCSLETFINFTKRR"
     gene            complement(9527..10093)
                     /locus_tag="ACOIAP_002635"
     CDS             complement(9527..10093)
                     /locus_tag="ACOIAP_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639516.1"
                     /translation="MNNLFYDKLNFDDKLIIKNNGVIRNNDLYFLKYKNDTAGILIYN
                     IINDKFSFKQNKNYKGMNPFPITNIFKNLDSDKWDEFIRIWIEERVIQECRPEVPFIL
                     KEFKLGYYDVWDICRSNLAMSVEDFFWITKDNTLRYEDFNIRYCTLNNITPIYKPPFP
                     IVIYPNYFEREKIKSGETWKYELKNTNS"
     gene            complement(10495..11547)
                     /locus_tag="ACOIAP_002636"
     CDS             complement(10495..11547)
                     /locus_tag="ACOIAP_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639517.1"
                     /translation="MNVINVFNINLKRNINKRIVFLVTLLFPIIIVILGVLANYISKP
                     FFNIGILDEYKNERVLKESEKRTYENTIMALENTQGINTKIADFKTIKTDIITGKYSA
                     VIYFNKNGFKLYSIKNKNTNDTLKYLIETYKKDPVPVDISKLQENTLGVLQRIIAFIV
                     LFLMITSTVTASMIIKDKNSGTFTRVLYSPQNVRGYVLGNMLYNFTITYFQYIVSISI
                     IKLFNIDIGMDYIDLILMGIWVVALATSFGTFVSSLFNREMHANLFSTCISLVLSLIG
                     GSFISVEKMPEMLQKISIISPVRWFISFVTYIEERDGSFFNMNYICILTSIIIVLALL
                     AMKFTQRSKYSSNSNY"
     gene            complement(11547..12287)
                     /locus_tag="ACOIAP_002637"
     CDS             complement(11547..12287)
                     /locus_tag="ACOIAP_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639518.1"
                     /translation="MRCFLPLFKLGIKRRSKDFFILFYNIVFPVIIIMLLGYLTSKSY
                     GEEFTSYNYYTIVTIPFCVLMGIISVSYAGQDEKISNTSYRYMISPISIVDLVISKLF
                     SCTAVLSICNLVTLVVLKCIFRMSFGGKFLAVLFFLMCESIVVVSMGLFLGLVCKNLD
                     MLRNIINIPIVIFGFLGGVFFPVSSLNPVISLIINISPLTWINRGIVACIYDNNLQLL
                     FNISCIFVVVSIFMTILTIKFFKKGVFI"
     gene            complement(12292..13050)
                     /locus_tag="ACOIAP_002638"
     CDS             complement(12292..13050)
                     /locus_tag="ACOIAP_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639519.1"
                     /translation="MSNILLEIKNLSKKYNNKEVVSIESFKLLEGDILGFIGANGAGK
                     STSINMLTTIVSPDSGSIYYKGKDIKNQQNIFKSSLGVVPQELAIYEDLSAYDNVKFF
                     CSLYGFKGNELKERTKDALEFVGLWESHKEFPSKFSGGMKRRLNIACAIAHSPKILIM
                     DEPTVGIDPQSRNKILEAIKCINTNGTTVIYTSHYMEEIETLCNRIALIDKGIIIEDL
                     DKSLYKNKYLEFGCKTLEDIFLYLTGTDLRDLEE"
     gene            complement(13152..13874)
                     /locus_tag="ACOIAP_002639"
     CDS             complement(13152..13874)
                     /locus_tag="ACOIAP_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGZ2639520.1"
                     /translation="MIRTLILYYLNIKPTHGYEIQKFLQVSGADRWTKIQSGSIYYAL
                     AKLEKDGGVRVLKEEKTGARIRKIYEITQSGKLELREEIQKELQMPIVPTGSNKFLLH
                     NILDVLPKDTLQKNLEKHIKYLIEQKKYWENWKEIKKIDKKSLATEKIAFDMTIDNLN
                     YQILWHEEILNDIDKYISVGCETQNIIKSIDFSNIEEDFLFTSDTTNELLEVQRLRDE
                     IINNPDKAIENIDKIILKLQNK"
     gene            complement(13975..14580)
                     /locus_tag="ACOIAP_002640"
     CDS             complement(13975..14580)
                     /locus_tag="ACOIAP_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2639521.1"
                     /translation="MKIKENVLRLDSTRGSNCFIVFDKEITLIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHMSNIKLLKEKTGAKVWAHTEDIPFIIGEKDRPGFKK
                     FIGKTISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVSYPNPWNWDSKKMMKSIRELDNLEYEWICMSHGTPCIK"
     gene            14760..15398
                     /locus_tag="ACOIAP_002641"
     CDS             14760..15398
                     /locus_tag="ACOIAP_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2639522.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFSLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSKKSDTEMLFKEKFFSFNKFMFDEIQEMFEIGKNDGSIRYDI
                     EISTLMYSSIFTLTGFFNLLSVTRKSYLNNFNIDEEKFIETTLAILIDSIKA"
     gene            15514..16176
                     /locus_tag="ACOIAP_002642"
     CDS             15514..16176
                     /locus_tag="ACOIAP_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639523.1"
                     /translation="MAKILLLEDDDTITFGIKTSLENKNHIVCCYNTIAEAKKNFDKT
                     TDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRAHSNTNNTITCGNISLNKVEVKAYLDSVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            16176..17357
                     /locus_tag="ACOIAP_002643"
     CDS             16176..17357
                     /locus_tag="ACOIAP_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2639524.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKVL
                     DASYEYNPKSTESILKSLKNSSDEDFKTGNEILSKHGYSKGTFWSKNFFYFLVVSFGI
                     ISTMAIVVYIIKYRTNKQKLSRINMLTRYLEEVNLGKESVLLRYEDEFSYLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TKQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     KGSPSIEFEIDINWTLEALLNILKNCSEHIEAGGHIIAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(17534..20194)
                     /locus_tag="ACOIAP_002644"
     CDS             complement(17534..20194)
                     /locus_tag="ACOIAP_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639525.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDDTYGKDLSLIENFSSVDDVMVKGQWYVGKINNDKRDYI
                     VYRNATSEYWNHMPEKDSIIEGRRPSNTNEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPVAPKSKGESFKKISKTTLTIVGKVDVATSSVVPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SNISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNKLIVYINSVNYHTDAPEVVFTYGIPAFLPAVLL
                     TIVTVWISTLIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTGFLHIIANQEGAEAVYGSDNYKDQRDIEVYLENSEPVE
                     SDFIEKLDNTEGVKNSLYYQKMSATTWLTEKDASKELSKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDESFAEYCRQISVDPKLFYDTKNPTSIVYNKEEDVNRSTRRNKVY
                     IDYLNLSIGDNIKLNEKIYDEDKGDYTYNMKVGAITSTLPKIIDTSSRYTLMQIVPIS
                     MVQEISKNYAEVGRSRSNRLIGLFKVDNREDIPRVRGKLESICNKDYGSGDYSIEDVV
                     ENEKQNGSGRKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPD
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYTFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYNQLKNENIVESIKSETI"
     gene            complement(20191..20874)
                     /locus_tag="ACOIAP_002645"
     CDS             complement(20191..20874)
                     /locus_tag="ACOIAP_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639526.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHMLGGVDRPTSGKIYVEDTEISSLNEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     TILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(21223..22155)
                     /gene="blaCDD"
                     /locus_tag="ACOIAP_002646"
     CDS             complement(21223..22155)
                     /gene="blaCDD"
                     /locus_tag="ACOIAP_002646"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HGZ2639527.1"
                     /translation="MKRKKNFIWTTILLVGIVMVMYYAGKKHNDINQKTDKNYIKSDL
                     NKSEINNDNNKKERVNIVNYSDCFEGISGGAIFYNSRNQEYNIYNKDLIETRASPCST
                     FKIISTLIGLEKGVITSKKSVIGYDGTNYPNKNWNKNLSLEEAFKESCVWYYKKLINK
                     VDAKSVQSILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMVKIF
                     EGDTNFKKEHINILKDIMKIDVSDKNINVYGKTGTGFNGKNKRVDAWFVGMLESKDDT
                     YYFAIKSDDSNKEIAGPKVKEIAINIIKKYYSVM"
BASE COUNT         7912 a         3204 c         2663 g         8612 t
ORIGIN      
        1 aaattgtatc aaaattaagg ttttgtgtta taacagtaaa agaaagagaa ctatattcta
       61 tttagtgaca gaattgagtt cgtaatttaa aataaaaaat tatttaaatt ttttgaactt
      121 gatttttaaa tcgaattcct agccactctt gccggagtgg ctttttaaat gcctaaataa
      181 tttacttaat aagttatatt ttgtattctt ttaatataaa aatgtgtgta atagaagatg
      241 aatacattaa gttaaaaatg tttaatgtac aactaactat tttattaaat ttaactttta
      301 tgttattgca tttttcttag atttagcaag agcattataa tttatttgat aacccaactt
      361 tcataatatg aacgatgtaa atcttctatc cattgtgata ctaataaata ttgctttcca
      421 taaatggaaa tagtgtaagc ataatatcta ttgtagtttt tttcatcttt tttcaattca
      481 ttaatattac catctttagg aacttctttt agtacaggtt tattttcatt aaacacttgc
      541 tttgaataac tggattgtgt catcttatca atttcttcag ggctaatttt ttcttcttca
      601 aaaagatgtt tcatagttac ttgaactaat ttcccaatct ttaattcctt taatgtttca
      661 tctgacaaat ttaattcaac tgcatctttt aaagaattag atttttttat tctttgttgt
      721 tttacaacat ctcgactata tgaaaacata ctgtacattt gataacttct taggaaaagt
      781 tctgatgtgt cagagattcc atcactagca attaagattg gttctaggat tttaccatta
      841 aattcttcat tcgcaattaa tctagtttta aatctcaatc ctaaagactt aaataggtca
      901 ttgacttctg ccatcttagg ttctaattca gttataatag ctggattaat ctttggagat
      961 gcaaatataa tttctgcttc atctaagtcc atataaccat aaatacacat tgctgtacgg
     1021 atacatttct ttataaccct tgtaacagtt tcatttttag atccataatt aagtcctgct
     1081 tcatgaaaag ctacatctat agcataaata tgatttcttc cattatctat tgaaatacct
     1141 aatacatcaa cttcagcttg cataattaat tgctccaatg aattattttt atatatagga
     1201 tatccatatt tctgctcaaa atattgttta gttttttcca taatttctag tattttatca
     1261 gcattcttta aatcccattt agatgacact ttccagtttg tttgcactat ttggcattct
     1321 ttaacatgac gtagccaaga atacaacagt gattctccca tttcaatctt catagaatta
     1381 ccatcctttt cagtctatta tctattaatt gttaaactat atctaaattc ttccatcata
     1441 tcttcaaatc atgtaatctc ttatttgtta tcaaaatcct tgagtcttat acatttacat
     1501 accttgttag gtaatattct attttagata aaagtattta tgcattgctt atcttttagt
     1561 ttacctaata ttgacaaaat tcttttttca cataaatcca taaattcatc aaatttatta
     1621 tcatcaaata aatcaaaata agcatcatta aaatttttga aattaggaca ttccatagta
     1681 ttattataaa tgtattccca acaaatccac catccattag tacgtgaacc atcatcattt
     1741 attaattctt ttatttcatc atcacttaga atctttccgc taggtttttc tttatataac
     1801 gtacaaaaac ctacaaatat atgatgatct atttcaattc ttagtaaaag atcaacatct
     1861 tctttatcta gactttttat aaaataatta attgctggat atgtagagct tttcttatta
     1921 taataattat tcactaaagc ataattattt tctttgtatg agtaatatgg taatttatat
     1981 ttatcttcaa atttcttatc catacgtttt tcaatttctt ctaaaacctt ttttatcatt
     2041 tgtgttttac ataactttaa tcctctttca atttctattg ctactcttat attttcttta
     2101 gatgataaaa tttctactat ctcatcctct ttttctagtg atgatacatt tgtcatattt
     2161 cttattacct ccataaattg cagtataatt tctcttattg gagctatttt tatagtttca
     2221 tgatgtgaga cacatttatt tagccaattt aatatatcta tttcaaaaga tatttgagta
     2281 acttctttat taaatatact attatttatt taaaacgagt tgcagttgtg tttttaataa
     2341 ttataactgg attattcaca ataactatga gtgttgatac ccttagaaat caatttatca
     2401 aaattgtaat agaaatttat gaagatttaa cagaatttat tttttctaaa gatattcaaa
     2461 ctgataagaa tcttgatttt atattaaaag aacccaaata tataccaaat ggtttcaaag
     2521 aggttgaaaa agaaaacaca ttacaaggta tctttattcg ctatgaaaac aagaatggct
     2581 ctgaaataag atatcgttcc aatcaaattg attcaaatac agtaatatta gatacagaga
     2641 atgcaaaagt cacagatatt atggtaaatg attatgaagc taaatatatt gttaaagaca
     2701 atagtattac aattttttgg aatgatgaag aaaatgtata tacaatatat tttgattatg
     2761 ataataaaaa tgatttaaat aagtataaag ataatcttat agatattgct gaaaatataa
     2821 aataattttt ttcaaaaagt gtcacaaatc accttttttt tcgttatatg agtatataag
     2881 aaaaaaggag gtgatatttg tgtatttaaa aaaagtgatt gtagcaggat tatgtacatt
     2941 aacttgccta ttacctttaa atgttcaagc ttttgaagat acttcattaa atactaatga
     3001 ttataatcaa acaaatgata atgatttatt tatgatttat attaaaggtg ctggtagtaa
     3061 tttgagtatt cgttctggaa aggctcatat atcttgttat gttgatggta aaattgggag
     3121 tttaacatca attacagcaa gactacagca aaaaaaatct ggtaagtggg taactatatc
     3181 aacatggtca agctcaggaa aaacttcaag tactttatct agagaatata gagtatcaaa
     3241 ggggtattct tatagaatat taacaacaat aaaagctgga aatgaaagta ggaatataac
     3301 aagtaatgta acaaattatt aatttaatta aaatttagga ggaatattat tatgaaatat
     3361 tttaaaaaag taattgcatt aggactatca attgcattgc ttattccagt aatttcaatc
     3421 aatgcattag aaaaaaaaga cacaaatgta aataaccaaa taataaatgt tatagaatca
     3481 aatgtatctt ataccaaaga gggtattgaa gtttcttctg acttgaaaaa tgatttgaaa
     3541 gaaattaact tagaagatat taaagaacaa atgatagagc aaggaattga ttcaaaattc
     3601 ataaataatt ttaatagtga cgtaatatat agtttagtta aagaaaatat agatgatata
     3661 aatgaaggag taaaaaataa aactcttaaa attacacctg aggaagatat tataaacaat
     3721 acagacaact cattttatgt acaaggaggt tctacatata ctcaaaaatt ttcatgggga
     3781 gtaagacaaa ataaaagtac tgcagcagca aatagatggg tttatgattt gaataagtct
     3841 tcacaaggat ttgtagcaac aggagcagta agtgttcttt taggttctat gggagcacca
     3901 ataggatttg tatctggttt atcagctgca tatatgggag gtcttgcaaa taaagtatct
     3961 tatgtaaatt cacgaaataa tagaggaata actgtggata taaactggtg gttaacttat
     4021 gcagtaaaaa atcagtaaaa attaggtgaa attaatgagt gaaaaacaaa acttaaatta
     4081 taaaaaaaaa atcttaaaac aataatattt atatcttgtt taataatttt atctatattt
     4141 atagttttta ataatataaa atctgactgt tggtatgtta attatatgaa ttatagtgat
     4201 atgcatgaaa tatctagtgg gaaaagtcaa aaaatagcat tgatagattc tggtatttca
     4261 aaatttcaaa aggtttataa aaatataaat ttaactaata gcaataatga ttatgataca
     4321 aatggtcatg gaacgatgat gtattcaatc ataaaaggtt ataataaaaa taatcaaacg
     4381 attgaaggaa tatctccaga ttctagaata atattaatta aagtaatgaa tgatgatgaa
     4441 agtattaatc ctaatgtaat agaagatgct atagactatg cattaaatga aaaagtagat
     4501 attattagtt taagtttagg atccacaaaa acagatatta atataaaaca aaaaatagat
     4561 aaagctaatc ttaaaaatat aacagttgta agttcagcag gtgattataa acaaggattt
     4621 ttgctatttc cagcatcttt aaataatgtt atttctgttg gtagcataga tgatagaaga
     4681 gatatttcaa cattgacaaa tgcacctcaa aagacattaa taaatgcacc tggagaaaaa
     4741 ataaaggtga tagataataa caataatgtt ttctatggaa agggaacatc agaagcaaca
     4801 gctattatta caggttacat agcgttgatg agagacacaa atatttctag tactcaaatt
     4861 ttaactaatg aaaaaattat gaatttatta tcccagataa acaaaaacga aaaaacatat
     4921 ttaggagcat taaaagaaat cagaaaaaaa gtatctgtaa gtacaggtgc ttttttctct
     4981 tttgatttat catattaaaa atagtgagaa atattttact tgaataaatt ctatttgttt
     5041 ataattatag tatgcattta aaatgagggg gaaaatagta tgttctataa caagcaaatt
     5101 aaaatattaa ctttattaat ttctatctta atagttttaa tatcagcact ttcttgtact
     5161 aatattatta aaaattttaa tttattaaaa ttttgtttaa tattatttgg agtggaacaa
     5221 attttactag cttataattc ttataagctt aataaaaatc taatggagac acttttatta
     5281 tgtattattg gaataatcct tataggtatt tctattgtaa ttatgtgaat ataaataaca
     5341 cgttttgaat ggaaaattat attaatttag ttcactaata ttacatcttt aatgcaagta
     5401 gagtaaagta ttttgaataa cataggtcaa tataaattgt aggagtgatt ttcaataata
     5461 tgtatattca aagtaacttt tctatttttg ttacttgcag gtttttatct tgaacaaacg
     5521 tataaatttt aataaaatat aaaaataaac tttatatttc aattacagat gatgatattt
     5581 tgattgataa taaatatatt tttagaggca agaatattaa aaactatatt aaatttaaag
     5641 atataacagg tgcaaataaa caggatagtc ttatatatct aaaagcttta agcattgaga
     5701 gagaagaata tctaataaat agactaaaat catttttctg atttcatata ttttaaagtt
     5761 ttaattaaaa gggttgcaga tattgagtta caaggtcttt tttgtaatat aaaaaacacc
     5821 actttgtgct cattacaaat ttcaatactt tctgtatcta aaagtattga aaatactcaa
     5881 tttattttgg aattttatac tacacatgca taaaacaatt ttaaaacaat tgcaatatta
     5941 attcattttt tttctaccat attatgattt gagttgcttt ttttaattat agaatttcct
     6001 aattttaatt cattctcaag atttgctttt gaaagtttaa gagattctaa tttatcatct
     6061 tctgtaaact tattctttaa aatttcttgg agagataaga gttcattttt cttaaatgaa
     6121 tatttttctt taaaactttc taatttattt gaactaattt tattataatc catgaaatat
     6181 ttaattagtg ttttaggact ttttgatgta gaaaattcaa atttatagtt attacctaga
     6241 gaaatgaatt ctctaacttt attgtcaaat gtaaattctt tttcataaat tatgttcaag
     6301 ccatatattt cacctaaaat tcctactttt ccattattta ttatatctga cagagcttct
     6361 atagcatctt taatatcaat ataagtttca ttatctaatg ttatcttaaa ttcattaaaa
     6421 aaaattagaa aaatacgttt taatatcttc ttctaattta gaaattgata tctttaaagc
     6481 atctattgaa ttttcggttg attttatgtc atttaaagta agtaaatttt gatttaaaaa
     6541 ggctttttta tttatttcaa ttatctgaat ttctctattt atctcacata attttaatat
     6601 gctatcatca gaacaggcac atgcctttgt ttcagcataa ctcataagct gattacctat
     6661 gtcttcagca gtcctagaag atgaagaatt attaagaatt tgagctatat attttgcctt
     6721 tatttctatt gtctgtcacg aatatgcatc aaaagaacct tcaactacat acctaaaaat
     6781 atagacctct ttattcaaat ttccttgcct taatattcta ccttctcttt gtgaaattga
     6841 tgaaggtttc caaggaacat ctacatgatg aagtgatttt agaggtagaa ccaattaata
     6901 ttctaataat accattattg aaatcatcaa taagtttctt tcttttttct ggagtattag
     6961 cgtcatgtat gtatgctata tctttttcta aaacattatt ttttagaagt tcatttttta
     7021 tatcattata aacattatgt gaatttccat taggagttcc tagatcacag aatactagat
     7081 gtgtacttat tttatcctca tgatataaag aagctatatt ttctccaact tttattatct
     7141 ttggtaatat accatcaatt ccaactaatg cagggcttac agccatcaaa cgaccatctg
     7201 tagttacatt taacatgtta tctattattg gatcatatgg gccttcatga attttttctg
     7261 cacgttttac aagagaatct atatattctt tcatttggtt tgtaggtttt ataatttcta
     7321 ttataggttt tccacctttt atctgaggaa tatctaaatc atttatgtca cagatgttaa
     7381 ctacatcagc aatttgtctg aatatattaa ctaattctgg aacattacag aatttagcaa
     7441 atctttgctg aaatctaaac ccttgaccag taggatctac ttccattgag gatataattg
     7501 aaccaaattt acttgcccaa gcattgaaag tatctacttt gtaatacttt aatgtatctt
     7561 tatttaaata agtgagtaaa gtatacattt cacatatact attagaaata ggtgtagctg
     7621 tggcaaatgt aacaccttta tttccatgaa tagatttaaa atatcttagt ttgttgtata
     7681 aatcctgtgt ttttttagtt tttaaagttg atataccagg gacttgcata gttgtattaa
     7741 aatataaatt tttgaagttg tgagcttcat ctatgaataa gtttgttatt ccaagctttt
     7801 caaatgaaag aagagcatcg tctttatgca tatcatttag ctctttgatt ctatttagat
     7861 aattttcttt cattgtttca agtcgttttg tagaaagatc agggcattct tttttgtaat
     7921 atttaagagt atcatttaat tcttttaagt ataagtctaa taattttaat tctgtatcag
     7981 cttctaaagg gattaatcct aataccgaat gtggaattat tatactatcc cagttgcatg
     8041 tcacaatttt agctataatt tttcttctat tggatttaga gaaatccttt gaagttgtag
     8101 ctaatatatt cgcttgagga tataaattaa aatactcttt agcaaattgt ccagattcac
     8161 aaagtgaatt tggtataaca aataaattct tattaccttt ctttgaatct attttagaaa
     8221 ttctatttaa ttcttgtgca gctgttatca ttgtataagt ttttccagaa ccaacactat
     8281 gacatagaag agtattacga tcagaagtaa ttattctact agccgctttt aattgatgtt
     8341 ctcgtaattt tatattagga tttattctaa catcatttaa tatattttta tattcctttt
     8401 ccttataatc tataaacatt tcattgtatc tatcaagtaa ttctttatga atataactat
     8461 tacttgttac atagttatga aaagctataa gccatttatt taatatgttc atagcaagtt
     8521 gagtttcttc caaattttta acagaaactt ctttaccatt ttgatattct ttatcagtga
     8581 cagttatagt tttcatattt aattctgctt caacaatata caaagatttt ctcctttttg
     8641 taccccatgt aaattcattt ttacttatag gtataatgtc agaacatttt actgaataac
     8701 caagttgtgt tgaatacaat aattgaattg aattttcttt gagttctaat gttttttcaa
     8761 taaaatcaga ttttatactt gaagatatcc aagtagaatc aatgctaaag aacacatctg
     8821 tttcatattt aggttgatta gcttctaaag ctttaacatt aaccaggaaa gtattatctt
     8881 ttattgatgc ttctttggct atttttaatt tttctttaac atatccactc aaataattat
     8941 ctctatctac taaatatcct gtcaaacggt caatataagc aagttgttta gataataatt
     9001 catttttgat attatgatat gattgattca tgatgctaca gatataatca atatttaaat
     9061 atcctttgta ctatctaatt ttgagtaaaa taatgtaact tctttttctt cattattttc
     9121 cttagattta aattttttta aaacagtgtt tgttccagct ggatatttta cttcaaatcc
     9181 tagattgaat aaaaatctcc ttgttttaag aatattttgt ttgttaattt cgttaaagtt
     9241 tttaaatgtt tcacctaatt tttttgatag agtaaagata aagtttttga tttcataaaa
     9301 acctcctttt attttttatg ctaatagtta cagcttattt ttatttgcta aagtatagct
     9361 ttaatttaat ttgtatataa tatggggcat ttagaagtct tttttgaaaa tttttataaa
     9421 aaatcaaaaa aactgttatt aaaatgattt ataatcactt aataacagtt ttaattatta
     9481 acattatttt ttatagtaca aataagaatg tataatctaa aaacgtttaa gaattagtat
     9541 tttttagttc atatttccag gtttcaccac tttttatttt ttctctctca aaataatttg
     9601 gatatataac aataggaaaa ggaggcttat aaataggagt aatattattt aaagtacaat
     9661 aacggatgtt aaaatcttca tatcttagag tgttatcttt tgtaatccag aaaaaatctt
     9721 ctacactcat agcaagatta cttctacaaa tatcccaaac gtcataatat cctagtttaa
     9781 attcttttag tataaaagga acctctggtc tgcattcttg aataactctt tcctcaatcc
     9841 aaattcttat aaattcatcc catttatcac tatctaaatt cttgaaaata tttgtgattg
     9901 gaaatgggtt cattcccttg taatttttat tttgcttaaa tgagaattta tcatttatta
     9961 tattatatat taagattcct gccgtatcgt ttttatattt taaaaaatat aagtcgttat
    10021 ttctgattac tccattattt ttgatgatta gtttatcatc aaaatttagc ttatcataaa
    10081 ataaattatt catataaaac tcccctctct tttaaatatt caattcttac ttttaacaag
    10141 tgtttaatac attttaatct atgttgtctc aaaagatctt tatatctatc aaattgtccc
    10201 tagaaaatag tatttttata cccttatttg ttatacataa ttttatttag aagataaact
    10261 ttatataaaa caattaaaaa tatttctatt aagataaata aaaaagagct atctcagaac
    10321 aaatttaatt tgctcatgtg acactatatt ataaaataaa aaaattttca cactattttt
    10381 tacactatat aatttctatt tttataatta aacccaattt ataagatata gaaccatatt
    10441 tatattttta tctcttgatt tgttttaatt acatatattt attttttatc ttatttaata
    10501 attactatta cttgaatatt tacttctttg agtaaatttc atagctaaca aagctaaaac
    10561 tattattata gaggtcaaaa tacaaatata attcatatta aaaaagcttc catctctttc
    10621 ttctatataa gtcacaaaac taataaacca ccttacaggg cttataatac taattttttg
    10681 caacatttct ggcatttttt caactgagat gaatgaacct ccaataagtg ataatacaag
    10741 tgatatacat gtagaaaata aatttgcatg catctctcta ttgaataaag aagatacaaa
    10801 tgttccaaaa gaagttgcca aagctactac ccatattccc attaaaatta aatctatata
    10861 atccatacca atatcaatat taaataactt aattatagat attgaaacta tgtactgaaa
    10921 atacgttatt gtaaagttgt ataacatatt ccctagcaca tatcctctta cattttgtgg
    10981 agaatacagc actcttgtaa atgtacctga gtttttatct ttaataatca ttgatgctgt
    11041 tacagtagat gttatcatta aaaataatac gataaatgca attattcttt gtaaaactcc
    11101 taaagtattt tcttgtaatt tacttatatc tacaggaact gggtcttttt tatatgtttc
    11161 tattaaatac tttaatgtat cattcgtatt tttatttttt atagaatata acttaaaacc
    11221 attcttatta aaatatatga cagctgaata cttgcctgtt ataatatcag ttttaattgt
    11281 tttaaaatct gcaatctttg tattaatccc ttgagtattt tctaaagcca ttattgtatt
    11341 ttcataggtt cttttttcag attcctttag aactcgttcg tttttgtact catctaaaat
    11401 accaatatta aaaaatggtt tacttatgta atttgccaat actcccaaaa ttactataat
    11461 tataggaaat aaaagtgtaa ctaaaaatac tattctctta tttatatttc tttttaagtt
    11521 aatattaaaa acatttatta cattcactat ataaagaccc cctttttaaa aaacttgatt
    11581 gtaagtattg tcataaatat gcttacaact acaaatatgc atgatatatt aaaaaggagt
    11641 tgtaaattat tatcatagat acaagcaact atgcctctat taatccatgt taatggtgat
    11701 atattaatga ttaatgaaat aactggattc aatgaactaa ctggaaagaa cactcctcct
    11761 aagaatccaa aaataactat cggtatatta ataatattac gtaacatatc taaattttta
    11821 caaacaagac ccaaaaacaa ccccatagat actaccacaa tagattcaca cattaaaaag
    11881 aaaagaacag ctaaaaattt tccaccaaaa ctcatacgaa aaatacattt taacaccact
    11941 aaagttacca aattgcatat cgaaagtact gctgtacaag aaaaaagttt tgaaataact
    12001 aaatctacta ttgaaatagg agaaatcata taacgatatg atgtgttaga aattttttca
    12061 tcttgtcccg catatgaaac actaataatt cccataagaa cacaaaatgg tattgtaaca
    12121 atagtataat aattatatga tgtaaattcc tcaccatagg actttgatgt caaatatcct
    12181 aataacatta tgattattac tggaaaaaca atattgtaaa acagaataaa aaaatcttta
    12241 cttcttcgtt ttattcctaa tttaaacaat ggtaaaaaac atctcatcta tttattcctc
    12301 caagtctctc aaatctgtac ctgtaagata taaaaaaata tcttctaatg tcttacaacc
    12361 aaattctaaa tatttatttt tatataaact cttgtctaaa tcttctataa ttattccttt
    12421 atctattaaa gcaattctat tacataaggt ttcaatttct tccatataat ggctagtata
    12481 tataactgtc gtaccattag tattaatgca tttgattgcc tccaaaattt tatttcttga
    12541 ttgagggtcg atacctactg ttggctcatc catgatgaga atctttggac tatgtgcaat
    12601 tgcacaagct atgtttagtc tacgtttcat tccaccagaa aattttgatg gaaactcctt
    12661 atggctttcc caaagaccaa caaattccaa agcatcttta gttctctctt taagttcatt
    12721 ccctttaaat ccatataatg agcaaaaaaa tttaacatta tcatatgcac ttaaatcttc
    12781 atatattgct aattcttgtg gtacaactcc aagtgaactt ttaaaaatat tttgttgatt
    12841 cttaatatct tttcctttat agtatatgct tccactatct ggagacacaa tcgtagtaag
    12901 catattgata gatgtacttt tccctgctcc atttgctcca atgaaaccta aaatatcgcc
    12961 ttccaataac ttaaaacttt ctattgacac aacttcctta ttgttatact tcttagataa
    13021 atttttaatc tctaacaata tattactcat ttataacccc ccaatattta accaacatta
    13081 tatatccaat attgtatata taattttttt aaaacacgag tattttaccc gtgttattgt
    13141 aataaaattt attacttatt ttgtaatttt agtattatct tatctatgtt ttctatagct
    13201 ttatctgggt tattaattat ttcatctcta agtctctgaa cttctaataa ctcatttgtc
    13261 gtatcagatg taaataaaaa atcttcttct atatttgaaa aatctataga tttaattata
    13321 ttctgtgtct cgcaaccaac ggatatatac ttatcaatat catttaatat ttcttcatgc
    13381 cataaaattt gataattcag attatctata gtcatatcaa atgcaatttt ttctgttgca
    13441 agactctttt tatcaatttt tttaatctct ttccaatttt cccaatactt cttctgctct
    13501 ataagatatt ttatatgttt ttcaagattt ttttgcaaag tatccttagg taatacatcc
    13561 aaaatattat gtaataggaa tttatttgaa ccggttggaa ctattggcat ctgaagctct
    13621 ttttgtattt cttcccttaa ttctaattta ccactttgag taatctcata gattttacga
    13681 atcctagctc ctgttttttc ttcttttaaa actctaacgc ctccatcttt ttctaatttt
    13741 gccaatgcat aatatattga cccagattgt attttagtcc atctatctgc accagatact
    13801 tgtaaaaact tttgaatctc atacccatgt gttggcttaa tatttagata atataaaatt
    13861 aaagtgcgta tcataaaaat ccaccaccta tactctatct tggatattat attatcacca
    13921 atcttggata tagtcaatag ataacatagg atatattaca acttattatt tttattattt
    13981 aatacaagga gttccatgag acatacatat ccattcatat tctaaattat ccaattctct
    14041 tatagatttc atcatctttt tagaatccca attccaggga ttagggtaag aaactatatt
    14101 tccattcttg tttttgacta aatcacctgc aaataataca tcttcaaaaa tcatgcagac
    14161 atgccctgga gtatgaccag gagtatggat aatttttata ttcccaatct gcatattctc
    14221 tccataaggt tcaacatcct taatgagcct tcttgaaatt gtctttccaa taaacttctt
    14281 aaacccaggt ctatctttct ctcctataat aaaaggtata tcttctgtat gagcccatac
    14341 ctttgctcct gttttctctt ttaataattt aatattagac atatggtcaa catcatgatg
    14401 agttaataaa atatgcttaa tatctgtaag tttgatacca agtgttttta attctttaat
    14461 tatatttttc cccataaaag gaagacctgt gtctataaga gtaatctctt tatcaaacac
    14521 aataaaacaa tttgagccac gagtactatc taaccttaat acattttctt ttattttcat
    14581 aaataaattc cccctatttg gtattttgcc tatataatta attaatgaag ttataaatag
    14641 ctataatact tgatattaat tttattttca ttaaagtata ctaatagtat acaaatatat
    14701 tatatttaca caagtatacc accagtatac tttattatca atagaaagga ataatttata
    14761 tgtcagaatt atcaaaaaga gataaagaaa aaatacaaag agaaaatgaa attattgata
    14821 aagcagaaaa attattttct cttaatggat ttgataatac aactatgaat gagttggcaa
    14881 aggaagtcga atatactaaa cgcaccatat acaagtactt ttcatgtaaa gaagatttat
    14941 tctttgctgt tgtcttaagg ggatataaaa gactttggga taatgttaaa atagaaagtg
    15001 caaaaggtaa aacagggttt gaaaaaataa aactttcata ctttgctttt cataaatttt
    15061 actctgtaga accttctcta ttatgcctta tgggaatgat tggtattgta aactctaaaa
    15121 aatcggatac tgagatgctg tttaaagaaa agtttttttc ttttaataaa tttatgtttg
    15181 atgaaataca agaaatgttt gaaattggaa aaaatgatgg aagtattagg tatgatattg
    15241 aaatatctac tcttatgtat tcatcaatat ttacacttac aggatttttt aatttattgt
    15301 ctgtaacaag aaaatcatac ctgaacaatt ttaatataga tgaggaaaaa tttattgaaa
    15361 caacccttgc cattttaata gactcgatta aagcatagac ctaagtatat aaattaaaat
    15421 ttatatactt aaatggtaat ctttactata tataatataa aaaatattaa gcataaaact
    15481 aataatttaa attaatgaaa ggactaaaag taaatggcta aaatacttct cttagaagat
    15541 gatgatacaa ttacgtttgg gataaagact tccctggaaa ataaaaatca cattgtatgt
    15601 tgttataata cgattgctga agctaaaaaa aattttgata aaactactga tttaattctg
    15661 cttgacttaa atctacctga tggtattgga tacgaatttt gccaatacgt taaaagtata
    15721 gaagatactc cagtgatatt tttaacagtc cgtgatgatg aaaaagacat tatacgtgga
    15781 ttagatatgg gtgcagatga ctatgtggtt aaaccatttt tgctttcagt acttcaatct
    15841 agaattaatg cagttcttag aagagctcat tctaatacta ataatactat tacttgtgga
    15901 aatataagtt tgaataaagt tgaagtcaag gcatatttag atagtgttga agtacctctg
    15961 acagcaggag aatataagct tcttctaagt cttatggaaa ataaaaatag agctatgact
    16021 cgtacaaaat tactagaaat gctctgggat gtagatggta atttcgtaaa tgacaacact
    16081 cttactgtta caataaagcg tcttagagaa aaattaaaaa atccaccttg tataaaaaca
    16141 ttaagaggta taggatatag aatggaggac agctagtgaa aactccaaga aatatcaaca
    16201 gtacagttgt ttttataata ttctgcttaa ttgtaacttt tttattgagt gtaattctaa
    16261 caactatcac ttcttttaat gaatacaatg tgctgtctaa ggttcttgat gcatcatatg
    16321 agtacaatcc taaatctaca gaaagtatac taaaatcact gaaaaattct agtgatgagg
    16381 attttaaaac aggaaatgaa attttatcaa aacatggata ttctaaaggt acattttgga
    16441 gtaaaaactt tttttatttt ctagtggtat cgtttggtat aatttcaaca atggctatag
    16501 ttgtatatat aatcaagtat agaacaaata agcaaaaatt gagtagaata aacatgctta
    16561 ctcgatactt agaagaagta aatttaggaa aagagtctgt acttttaaga tatgaagatg
    16621 aattttctta tcttgaagat gagatatata aaacagttgg ggaacttcgt tgttcaaaag
    16681 aatttgctct aaaagaaaga caaactcttt cagataacct tgcagatatt gctcatcagc
    16741 ttaagactcc aattacttct atgtcactta tggcacaatt actttcagaa aattgtccag
    16801 atgaagaaat agattatatt aacaggctta caaagcaaat atcaagactt gagagactag
    16861 tttcatcttt acttacctta tcaaaattgg atgcgagtac tttaatattt gaaagcaaac
    16921 ttatagatgt acattctctt cttacttatg caattgagcc tatagaaggt tctttaagag
    16981 aaaaacatca gacatttact atcaaaggtt ctccttcaat agaatttgaa attgatatta
    17041 attggacttt agaagctctt ttaaatattc ttaaaaattg tagtgagcat atagaagctg
    17101 gtggacatat cattgcttat tatagtcaaa accctctata tgttgagatt atcatagaag
    17161 ataatggtaa ggggtttgct caggaagagc tcccatatat ttttaataga ttttatcgtg
    17221 gtaaaaacgc tagtaaggac agtattggta tagggcttgc tctatcaaag tctattatag
    17281 aacgtcaaaa tggtactcta catgcagaaa attgccataa tggtggtgca agattcataa
    17341 ttaagtttta cacataaaat actggattat aggtaaaata cccataatcc agtcatatct
    17401 atatcctatg ttatttatta ttttagtaat ccgctattta tatctaagat tttattaaat
    17461 aaacaattta actatctcta tactcgtaag tattcttgaa ttgaaaccat aaataagttc
    17521 agataacttt tatttatatt gtttcacttt ttatagattc tactatattt tcattcttca
    17581 actgattgta tcctgtcata tatgatgcta ttacaataaa aagtatcaat atagtaaaac
    17641 ctattattgt agatataggt gcaaatggta aatactctat aaaatatatt tcatttatac
    17701 gtagaaaagt atatactatt cctatttgca caggaatact aagtagtaat ggtgtaattc
    17761 ctaagaataa accttccaaa acaagcatct tttttatgcc atctggagat aatccaacag
    17821 aacgcaacat agcaaactct tgtcgtctac ttctaatatt tcctgacact gtagcaagta
    17881 catttgataa tccaatcata gccaataaac ctgtaataaa acctactatc aaattcatag
    17941 tctttcttcc actaccattt tgtttttcat tttctacaac atcctcaata ctatagtctc
    18001 ctgaaccata atctttatta caaatagact ctaattttcc tcttactcta ggaatatcct
    18061 cacgattatc tactttaaac aatcctatca gtctatttga acgtgaccta cctacttcag
    18121 cataattttt agatatttct tgcaccatag atattggtac tatttgcatt aatgtatatc
    18181 ttgaactagt atctattatt ttaggaagtg tgcttgtaat agctcccact ttcatgttgt
    18241 aagtataatc ccctttatct tcatcatata ttttttcatt taatttaatg ttatctccta
    18301 ttgaaagatt taaataatct atatatactt tatttctacg tgtgctacga ttaacatctt
    18361 cctccttatt atatacaatt gaagttggat tttttgtatc ataaaataat tttgggtcta
    18421 cagagatttg tctgcaatat tctgcgaaac tctcatcatc aagcccaatt atatttgaaa
    18481 ttatacgaaa cttgccatca cgctctatag gagagtactt tttagatgaa actatacttt
    18541 taaatcctcc atttttcgaa agttcttttg aagcatcttt ttcagtcagc caagtggtag
    18601 cagacatctt ttgataatat agtgagttct ttacaccttc tgtattatct aatttttcaa
    18661 tgaaatcaga ctctacaggt tcactatttt ccaaataaac ttctatatct ctttggtctt
    18721 tataattatc acttccataa acagcttctg ctccttcttg atttgcaatt atatgcaaaa
    18781 aacctgtcag taataaaaaa gataatgtta aagatattgt tgcagtacga taagattttt
    18841 tacgagcacg tagtgcattt gatgcaagtt ctccttctat tccaaatatc tttcctaatg
    18901 aatatttatg tgacttttta attttaacac tatctccttg tcgtattgct tctataggag
    18961 atatttttga tacttttcgt gctggtatga gtgtagaaat ccagactgtt actattgtaa
    19021 gtaaaactgc tggcagaaaa gcaggaatac cataagtgaa tactacttct ggagcatcag
    19081 tatgataatt aactgaatta atatagacta taagcttatt acacaataac caccctaaaa
    19141 ataaacctat tggtaatggt ataatagtca ataaaaaacc ttcaaacact acagaccttt
    19201 taatctgttt tggtgatgct ccaacactag ataatattcc taattgtgta agtctagcat
    19261 ttgcagatag tgaaaatgcg ttgtaaatta ccattacaaa cacggctact gtaaaaattg
    19321 ctattgtaag atacataata ggagttgaaa attttgatat attgctcata gatgctttct
    19381 gttctggaga aaagactaac atttttaaaa gataattact attgtattta agattgtatt
    19441 ttccatattc attagtcttc catcccaatg atttagcaag ttttggaagt tccttatatg
    19501 tgtctcttat atttttaaat cgcaagtaca cagttatact gtcattaggt tttatacttg
    19561 ttttatcaag atatccaaga gctgtatatg caggtacaac tgatgaagta gcaacatcta
    19621 cctttcctac tattgtcaat gtagtctttg aaattttttt aaaactttcc cctttcgatt
    19681 ttggggctac aggttcaaga ggctttccat ttaggattct atctcctatt gggagagtaa
    19741 ttttatcacc aatttttaca cttggattat tctcaaaata ttgttttgat agtgcaattt
    19801 cattagtatt acttggtcga cgcccctcta ttatagaatc tttttctggc atatgattcc
    19861 aatactctga tgtagcattt ctataaacta tataatctct tttgtcatta ttaattttgc
    19921 ctacatacca ttgtcctttt accattacat catcaactga agaaaaattt tcaattaacg
    19981 ataagtcttt tccataagta tcgtcaaaca attcaccatg ccagttaccc tctttctcaa
    20041 ttgaaagtct tataaaatct gtccacatgg tatacaacaa tccacacaag gaagacatca
    20101 tggttgtggt aagtaatatg gctaacatta tagctatact actacgttta ttgcgtcgta
    20161 caaagtctaa ggtatattct tgaagaatat tcatttcttc accacctttt cagagacaat
    20221 cactccatct tccatagtta caatacgatt tgcctctagt gctattttct catcatgagt
    20281 aataagaagt attgtctgat taaatcgttt atttgataag tttaacaaat ctacaatttc
    20341 ttctgaattt tttctatcga gattaccagt tggctcatct gctaataaaa tagttggtct
    20401 atagattaaa cttctagcta tagataccct ttgttgttgc ccacctgaaa gttgacttgg
    20461 aagatgattc aatctatcag ataatcctaa tatagataca atctcagaga atctatcttc
    20521 atccaccttt cttttatcaa gtaacatggg taataatata ttttttctaa catcaagagt
    20581 aggtataaga ttataaaatt gataaataag acctactttt ctacgtctaa aaactgcaag
    20641 agcttcttca tttaagcttg atatttctgt atcttcaaca taaatctttc cagatgtagg
    20701 tctatctact cccccaagca tatgtagcaa tgtagatttg ccagaaccag atgctcctac
    20761 aatggataca aaatcacctt tttgaactga taaatttaca ttattaagag ctgtcactct
    20821 ggtttgattt gaaccatata tttttgtgag attttcacat tttaatattt ccatatacac
    20881 tcatctcctt tatggttaaa ttttagcaac ctaaaatgac attatagtga catgaataca
    20941 aatatcgatt actattaaaa atattgttta gtttttgaac attatttaaa attataatac
    21001 aaaacaaaaa ctatgcaata tattttattt atacttttaa tatattgcat agcctttaaa
    21061 agatattaac tttaatatct ataagtattc aatttaataa tcaatagcaa gtattttata
    21121 tactagagga gttttgctct atgtaaactc aatttagtaa aattatttaa taaatattta
    21181 cagactatag gtaaccaata tttacaaata aaattaagtt tattacatta cactataata
    21241 tttcttaatt atattaattg caatttcctt tacctttggt cctgcaattt ctttattgga
    21301 atcatctgat ttaatagcaa aataataagt gtcatcttta ctctctagca taccaacaaa
    21361 ccatgcatct acacgtttat tttttccatt aaatcctgtt ccagtttttc catatacatt
    21421 tatattttta tcacttacat ctattttcat aatatctttt aaaatattaa tatgttcttt
    21481 tttaaagttt gtatctccct caaatatttt caccattgtt tgcacttgtt cttttggaga
    21541 tatttgtaat gaagattcta accaaaatcc atttaaatgc ccctttccat tttttaaatc
    21601 tccttcccat tcactaatat cacagttccc atactttaaa tcatctaaaa tactttggac
    21661 agatttagca tcaaccttat ttatcaattt tttgtagtac caaacacaag actccttaaa
    21721 tgcctcttct aaactaagat ttttattcca atttttattt ggataatttg taccatcata
    21781 cccaataact gatttttttg acgttattac ccctttttct aaaccaatta atgttgaaat
    21841 tattttaaaa gtagaacaag gtgaagctct tgtttcaatt aaatctttgt tatatatatt
    21901 atattcttga tttctgctat tataaaaaat agctcctcca ctaatacctt caaaacaatc
    21961 actatagtta actatattaa ctctttcttt tttattgtta tcattattaa tttcagattt
    22021 atttaaatca gattttatgt aattcttatc agttttttga tttatatcgt tatgtttttt
    22081 acctgcataa tacattacca taactatacc aaccaacaag atagttgtcc aaataaaatt
    22141 cttttttctt ttcataattt atatcatctc ccatatttaa atttataacc tacttttaaa
    22201 atagtagaca ttatttgtaa tatacttcaa tctaggtgct acttataaaa aataagacta
    22261 aaggaataac tatatatctt atattttctt cacctagcac aactatgtcg attaaaccta
    22321 ttacgaaaat aattaggtaa ctattaatag cattttgtcc tccttttaat ttgtgatata
    22381 gtatttgatt c
//
LOCUS       DBGJFK010000059        22351 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.059, whole genome shotgun sequence.
ACCESSION   DBGJFK010000059 DBGJFK010000000
VERSION     DBGJFK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22351
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.059"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            114..230
                     /gene="rrf"
                     /locus_tag="ACOIAP_002647"
     rRNA            114..230
                     /gene="rrf"
                     /locus_tag="ACOIAP_002647"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            684..1754
                     /locus_tag="ACOIAP_002648"
     CDS             684..1754
                     /locus_tag="ACOIAP_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639528.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGKLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGNPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVITKEVLGNETIYCLSVLNSEIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDLKICKNMYSKIKGDIYEKAI"
     gene            1738..2607
                     /locus_tag="ACOIAP_002649"
     CDS             1738..2607
                     /locus_tag="ACOIAP_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGZ2639529.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2651..3511
                     /locus_tag="ACOIAP_002650"
     CDS             2651..3511
                     /locus_tag="ACOIAP_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGZ2639530.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIIQFLVMVP
                     AAYAFSKIKFKGEKVLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQVSDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3542..4846
                     /locus_tag="ACOIAP_002651"
     CDS             3542..4846
                     /locus_tag="ACOIAP_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2639531.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNPNDSNASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQKRFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4909..6171
                     /locus_tag="ACOIAP_002652"
     CDS             4909..6171
                     /locus_tag="ACOIAP_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HGZ2639532.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKKLPNFKSILEDCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKVKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNKHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNEEVDKALKMNDKWLG
                     DIIQATKDAGTYEDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKNFDAYV
                     DSSGISAQIIVNNLDRLTELRELLEEFKEELFIEKIFTKEEASNLGLEGDFEMVIEGI
                     EGISFGNDLEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKSGVVIEEGD
                     LRAHAATILKIFDLKLDGVEKEAFDFIV"
     gene            6357..8327
                     /gene="uvrB"
                     /locus_tag="ACOIAP_002653"
     CDS             6357..8327
                     /gene="uvrB"
                     /locus_tag="ACOIAP_002653"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGZ2639533.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIIEIEDELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNITPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8346..11171
                     /gene="uvrA"
                     /locus_tag="ACOIAP_002654"
     CDS             8346..11171
                     /gene="uvrA"
                     /locus_tag="ACOIAP_002654"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGZ2639534.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLIATLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFAATNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPREVSKVDGSYTGQFLKKYFS"
     gene            11434..13251
                     /gene="uvrC"
                     /locus_tag="ACOIAP_002655"
     CDS             11434..13251
                     /gene="uvrC"
                     /locus_tag="ACOIAP_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGZ2639535.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSCILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEAN"
     gene            13251..14180
                     /gene="hprK"
                     /locus_tag="ACOIAP_002656"
     CDS             13251..14180
                     /gene="hprK"
                     /locus_tag="ACOIAP_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGZ2639536.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14394..16190
                     /locus_tag="ACOIAP_002657"
     CDS             14394..16190
                     /locus_tag="ACOIAP_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HGZ2639537.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVVSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVIIE
                     RQMAIKELLSKDDFSIHIQTLSNIIGKEQKSNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTAIILSFIFCVLGFLPVLPVFLLFIIQLGFSGFGYPKLMQTLSPLFSFSRSIQ
                     VYEKMFEVLEKETFESVYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQIIYIIA
                     CGVLMWNYHCAEALERWKGVYGNQIRDWFESIGEFEALISLTVISHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSRPWVISMVTTHDFELCDLSGNGDVEVVNYHFSEY
                     YVDDKIHFDYKIKYGRCKTTNAKQLMRMAGIL"
     gene            complement(16330..18111)
                     /locus_tag="ACOIAP_002658"
     CDS             complement(16330..18111)
                     /locus_tag="ACOIAP_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent [FeFe] hydrogenase, group A6"
                     /protein_id="HGZ2639538.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCIYGECPQECACEEAK"
     gene            complement(18134..20020)
                     /locus_tag="ACOIAP_002659"
     CDS             complement(18134..20020)
                     /locus_tag="ACOIAP_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region domain-containing protein"
                     /protein_id="HGZ2639539.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(20037..20534)
                     /locus_tag="ACOIAP_002660"
     CDS             complement(20037..20534)
                     /locus_tag="ACOIAP_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HGZ2639540.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(20852..22333)
                     /gene="cls"
                     /locus_tag="ACOIAP_002661"
     CDS             complement(20852..22333)
                     /gene="cls"
                     /locus_tag="ACOIAP_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGZ2639541.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKIGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
BASE COUNT         8572 a         2990 c         3749 g         7040 t
ORIGIN      
        1 tcattcatta agatatatgt gtagttttta gagtgttaac tctaaaagaa ctagtcttac
       61 tagattctaa aaaattatta aaaacttaat agaaatatta agcataaaga ttatgtggtt
      121 gcaatagcag agaggataca cctgttccca ttccgaacac agaagttaag ctctctagcg
      181 ctgatggtac ttggtgggaa actgcctggg agagtaggac gtagccacgt aatttttttg
      241 ggtaaattta taaaaattaa aaaagtttta ttttttatgt ttagaccttg taaatttggg
      301 acataatata attgtaaaac ttaatatagc aaaaataaat tactcaatct cccccactta
      361 aagacctcta tcccccatag aggtcttttt tattttcaaa ccaaatcata taaaagaata
      421 aatagtttta tatgactctt cataaattta aattacattg tgatagcaaa ccatgaatat
      481 gaaaatatag aaaattatag ctaatataag ctgtatatca tcttaacttc agtatattta
      541 acaaaaaatg tttataattt aacctttatt ttaataagtt taccatatat tcacttagtc
      601 ttaatatatc ctttacaaat taagagtatt attaatctat aagtaaatag tagaattaaa
      661 ttaaatattt tgggaggata aaaatggcag atataagact agaaaatgta acaaaatctt
      721 ataataaaaa aaatacagtt atagaaaatt taaatcttac tatagaagat ggttctttta
      781 cagtattggt aggcccaagc ggatgtggca aatctactac attaagaatg attgcagggc
      841 ttgaagatat aacttcaggt aagttgaaaa ttgaagaaaa tgacgttaca aaaacggatg
      901 ctagtaaaag ggatatagct atggtctttc aaaattatgc attatatcca catatgactg
      961 ttagagaaaa tatagaattt ggtcttaaaa ataaaaaagt agaaaaagaa aaaagagaaa
     1021 aacttataac agaagttatt gatgtagtag gattaagaga atatttaaat gtgaaaccag
     1081 ggaacttatc tggaggtcaa agacaaagag tggcacttgc tagagctatg gttaaaaatc
     1141 caaaggtatt tttaatggat gaaccattgt caaatttaga tgctaaatta agaaatcaaa
     1201 tgagaacaga attaatacag ttacatcaaa aactaaaatc tacatttgtt tatgtaactc
     1261 atgaccaggt tgaggcaatg tcgatggcag ataagatagt tataatgaac aaaggaaaga
     1321 taatgcaaat aggttctcca aagaagatat atcaaaatcc taaaaattta tttgtagctc
     1381 aatttatagg gaatccttgt atgaacatac tagatataaa aaatgatatt aagtttggat
     1441 ttagaccaga aaaagcaaca ctagaaagta taaatataga tggaaaaaat gatgatgtat
     1501 ttagcttatt tggaaaagtc attactaaag aagtgttggg aaatgaaact atatattgtt
     1561 tatctgttct taatagtgag ataagagtca aaacggaaaa tgatatattt gatattggaa
     1621 gaactttaag aataagtgta ttagaaaaag atttatatta ttttgataaa aatggagaaa
     1681 gaatagaaga tttaaaaata tgtaaaaata tgtattctaa aattaaagga gatatttatg
     1741 aaaaagcaat ttaataaagc atatttatat ataacacctg ctattatagg aactttattg
     1801 tttatagtct atccaataat taagacgata tctctaagct tcaaatctgg tagtcttctt
     1861 agttcaacct ttgagaatgt gggcttgaac aattatacag aacttttaaa gaacccagag
     1921 tttatacaaa ctataacgaa tactgcaatt tatacttttt ttatggtgac tatatccata
     1981 tcattagcca tagtacttgc tgtttggcta aataaaaatt ctataataca caatttaacg
     2041 caaagtataa tctttacacc acatgtaatt tcactagtat ctgtagctgt attgtggctt
     2101 tggattatgg agccacaata tggcttttta aactggatac tatctacatt acatttacca
     2161 acatcaaagt ggctttcaag tgaaagctct gctttaatgt cactaattct aataggaata
     2221 tggaagactc ttggatacaa tattttaata gtattatcag gtcttaaatc cataccaaat
     2281 tatatatatg aagcatctaa gctagataat gcaaacaaga taactaattt ctttaaagtg
     2341 acattgccac tattatcacc aacaatattt tttcttatga taacaacaac aactgcatct
     2401 tttcaagtat ttgatgagat aagtataatg acacagggtg gtccagttgg ttcaaccaat
     2461 atgctatctt attatatata tgagtctgga tttatatatt atgacatagg gcaagcgagt
     2521 gcagcgagta tgtttttatt agctatagtt atgattgcta catatgctaa ctttagacta
     2581 ttatcaaaaa aagttcacta tcaataaaga agaaatagat attataaggc ttatcaagaa
     2641 ggaggagaaa atggatatta tacaacctat caaaaaagac aaagttgata taaaaaaaat
     2701 agcatcaaaa tcaatagaaa tattaattct attactttta tctgcaatat ttatatttcc
     2761 ttttatatgg atgttatcga catcctttaa aaatccgcaa gaaatgatgc aattaccacc
     2821 tacaattata cccaatgata tagtgttaga aaattatagt acagcatggc attcaggtcc
     2881 attttttaga tatttgctaa acagtgtatt tgtaacagga agtgttttaa ttatacagtt
     2941 tttagttatg gttccagcag cgtatgcatt ttctaagatt aaatttaaag gtgaaaaagt
     3001 gctatttgga cttttgcttg taggacttat gattccacca caagtaactt ttctaccagt
     3061 ctatatgatg atgagtaagt ttggatttat aaatacgtat gttccgctta taattccatt
     3121 tatgacatct tcatttggga tatttcttct tagacagaat tttatgcagg tttcagatga
     3181 aattattgaa gcagctaaac tagataatgc ttctgactta aaaataatgt ttagaataat
     3241 ggttcctatg gcaaagccag cagtaataac atttatatta tttaatttta tataccattg
     3301 gaataattat ttctggccct tagtaatgac aaatacagat gcaataagaa ctttaccaat
     3361 aggagttgca ctccttaaat cttcagaagg aattactgca tggaatgtaa taatggcagg
     3421 aaatataatt ctaattttac caataattct tgtttatata tttgcgaata aaaaagtaaa
     3481 agaagctttt atgtattcag ggataaaata aaaaattaaa gactaaattt ggaggatgaa
     3541 aatgaagctt aaaagaaaat tagcaacagg attagcaata acattattat taggttcttt
     3601 agttgggtgt tcaaatccta atgattcaaa tgcatctaaa ggagaaaaga ctgatagcaa
     3661 tattacaaag atagatttct gggctccttt aggtggaact aatggagaaa ctgctcaaaa
     3721 aatggttgac cagtttaata gtgaacataa ggatgtacaa gtaaatatgt taaagcagaa
     3781 agattactat gaaaatgcaa caaaactaca agcagcctta acatctaaag accaaccaga
     3841 tgtaacatta ttagaaataa ctcaaacagg tacattcgca tcagcaggtg ctttagtaga
     3901 tatgagtaaa tattttgata aaacatatca aaaaagattt ttttctggtc ttttaacaaa
     3961 ttcatattat gaggataagt ttgttggtat gccatttaat agaagcactc caatattata
     4021 cataaataaa gatatggcaa ctaaagcagg tcttgaccct tcaggtccaa aatcatggga
     4081 agagcttaag gattatgcta gcaagatgac aaataaatca gaagacactt atggttttga
     4141 aacaccaata gatatttggt tctatgaagc tatggtaatg caaagtggag gagaaataac
     4201 taatggtaaa aaagtagcat ttaataatga agcaggacaa gctccagtta agttttggca
     4261 agatatgatg aaagctggaa taatgaaaat gcctcctgga gaagattata atgcttggga
     4321 tgtagcaaaa caagattttg taaatggtaa agtaggtatg atatttacat caacagcaga
     4381 tttagcagga cttatgcaac aaacagaagg aaagtttgaa atatcaacag cattcttacc
     4441 aaaaaatcaa aaatatgcaa ctcctacagg tggtgctaat ctagttatgc ttgaaggtgg
     4501 aacagataaa gaaaaagaag caagtgcaga atttatagag tggatgacac aaacagataa
     4561 aatcgttcag tttagttcat caacaggata cttaccaaca actgaagatg caacaaactc
     4621 agaaaagtta caaacattat ataaagaaaa acctcaatat aaggttgcaa ctgaccaatt
     4681 acagtatgct gttgcacttc caatgttaaa tggatataag gaagcaactg ataagctaat
     4741 ggacgagatt aaaaagggac ttactgattt aaatgcaaat ccaaaagatg tagtaagcaa
     4801 aggaacttct gcaatgcaag cagtaataga taaaacaaat aaataattat atagacttgt
     4861 aagttgatta gaagtattca ataatatata aatgaagagg taatgtaaat gacaaaggtt
     4921 atagtattat cagtggattc tttatttgaa aaagatttgg aatttgtaaa aaagctacca
     4981 aactttaaat ctatactaga agattgttcc atagtgaaaa atataaattg tgtttatcct
     5041 actctgacat atccatgtca tactagtatg gttacaggag tatatcctaa aaaacatggt
     5101 atatatcata atgaaaaatt tgacccaaat aaagaaaata aagattggta ttggtattca
     5161 aaggacataa aagtaaaaac tattatagat gtagcaaaag aaaataatct aactacctct
     5221 agtgtattat ggcctgtaat gggagcaaat ccaaatatag attacaatat tgcagaaata
     5281 tgggctccta gtagagaaga tgacccaaga gaaacgtttg aacgaagttc cagtaaagtt
     5341 ataatggatg gtatttacaa taaacattgt cattatattg attggaaact agaacccaat
     5401 atggatttgt ttggagtaaa ctgttcagta gatataataa aggaatataa gccagattta
     5461 atgttaatac atttagctac attggaccac acacgacaca attatggctt atttaatgaa
     5521 gaagtagata aagcattaaa aatgaatgat aaatggctag gagatattat tcaagctaca
     5581 aaggatgcag gtacatacga agatacaaat tttataatac ttggcgacca tggtcatctt
     5641 agagttgata aagttataaa tccaaatgtc ttgcttaaat caaatggatt tataaaagtt
     5701 gaaaatggag aagttaagaa ttttgatgcc tatgtagatt cttctggaat atcagctcaa
     5761 ataatagtaa ataacttaga taggttaaca gaattaagag aacttcttga agaatttaaa
     5821 gaagaattat tcatagagaa aatttttaca aaagaggaag catctaacct tggtcttgaa
     5881 ggtgattttg aaatggtaat tgaaggtatt gaaggtattt catttggaaa tgatttagaa
     5941 ggaagtatta taaaagattc tgatataaaa gattataagt ttgctgttgc gacacatggt
     6001 catttaccta cgaaaggtaa tagacctcca tttatagctt ttggaccaaa tattaaaagt
     6061 ggtgtggtta tagaggaagg agacctgaga gcacatgcag caactatatt gaagatattt
     6121 gatttaaagc tagatggtgt tgaaaaagaa gcatttgatt ttattgtata agttgaataa
     6181 agtatttatt ttccatgaat tatagacttc tattgcaaag atagaagtct ttttttatgt
     6241 tttagattta ggtaaaattt aaatgggtaa aatatttaaa ataacttaaa caattttata
     6301 aaggtatgat ataataatac atgtcaggaa ctaatgttcg aaaaaggagt gatactatgg
     6361 attttaaaat aaaatcagac ttcaaaccta caggtgacca accagaagct attaaatcaa
     6421 tagtggattc tataaataga aatgagaaat tctcaacatt attaggagta acgggttcag
     6481 gaaaaacatt cacaatggca aatatcattc aacaagttaa gaaacctacc ctaataatgg
     6541 ctcataataa gactttagca gcacaacttt acagtgagtt taaagaattt ttcccagaca
     6601 atgcagttga atattttgta agttactatg attactatca accagaagca tatgtagctc
     6661 acagtgacac ttatatagag aaagatgcaa gcataaatga tgaaatagac aaacttcgac
     6721 attctgctac agcatctatt ttagagagaa gagatactat aataatatca tctgtatctt
     6781 gtatatatgg acttggtgac ccaaaagact ataaagaact tatgttatct ataagaccag
     6841 gtatgcaaag agatagagat gatgtaataa aaaggttaat agagatacaa tacgaaagaa
     6901 atgacataaa ttttacacga ggtactttta gagttagagg agatatacta gaaatattcc
     6961 cagctagtaa tgatgaaaaa gcaataagaa tagaattttt tggtgatgag gtagatagaa
     7021 taacagagat tgattatgta acagggaaga ttgttggtac tagaaatcat gttgttatat
     7081 ttccagcatc tcactatgta acaacaccag aaagaattga aaaggcaatt atagaaatag
     7141 aagacgagct tcaagaacaa attaaatttt tcaaagaaaa tgataggcta ttagaggcac
     7201 aaagaatcga acaaagaact aagtatgata tagaaatgtt aaaggaaata ggattttgtc
     7261 aggggataga gaactattct agacatatta caggaaggtc agaaggagaa agaccatata
     7321 ctttaatgga cttctttcca gatgactatt tgataattgt agatgaagca catgttacta
     7381 taccacaagt aagaggtatg tatgcaggag ataggtctag aaaaacatcc cttatagaga
     7441 atggttttag attaccttct gcacttgaca atagaccatt aaattttcaa gaatttgaag
     7501 gaaatataaa tcagatgttg tttgtaagtg ctacaccagg accttatgaa attcaacact
     7561 cagagacaat agcagaacaa ataataagac caactggact tttagaccca attgtagaag
     7621 taagacctat aaataatcaa atagatgatt tggtaggaga aataactaaa actatagaaa
     7681 aaaatgaaag agtgcttata accactttaa ctaaaaaaat gagtgaggac ttgactaatt
     7741 atcttaaaga aatagggata aaagttaaat atttacactc agatatagtt acattagaaa
     7801 gaacagaaat aataagagat ttaagattag ggaaatttga tgttcttgta ggaataaatt
     7861 tacttagaga aggattggat ataccagaag tttcacttat agcaatttta gatgcagaca
     7921 aagaaggttt cttacgttcc gaaacagcct taatacagac tattggacgt gcagctagaa
     7981 atgaaaatgg aagagtaatt atgtatgctg atagaataac tgactcaatg caaaatgcta
     8041 ttgatgaaac aaagagaaga agagatatac aaaatttata taatgaagag cacaatatca
     8101 ctcctaaaac tatacagaaa aatataagag atagtataga agctactaag gtggcagagg
     8161 aagaagttgt atatggaata tctgatacag atgataaaga tgaaataaga gctaatatag
     8221 ataaattaaa atcagagatg atggaagctg ctcaaaactt acaatttgaa agagcagcag
     8281 aacttagaga taaagtgaaa caattagaag aaaaattgga aaaatagaaa ggtaaaaaca
     8341 acattatgga agataaaatt ataataagag gagcaaaaga gcataattta aaaaatatag
     8401 acttagaatt accaagagat aaatttattg tttttacagg tttgtcaggg tctgggaagt
     8461 cttctttggc atttgataca atatatgcag aagggcaaag aaggtatgta gaaagtctat
     8521 ctgcttatgc tagacaattt ttaggtcaaa tggaaaaacc aaatgtagag tatattgagg
     8581 gtttatcgcc agctatctca attgaccaga agactacttc aaaaaaccca cgttctactg
     8641 ttggaacagt aacagaaata tatgactatt taagactatt atttgcgaga gtaggagatg
     8701 tgtattgtcc tacatgtggt gaaaaaataa gtcagatgac tattcaagaa atagttgata
     8761 aaatgttaga ttttccagat agaacgaaat tacaaatact ttcaccaatt gttagaggac
     8821 aaaaaggtac acataaaaaa gtttttgata atattaaaaa agaaggattt gtaagagtta
     8881 gagttaatgg tgaaaactat gaagttagtg atgatataat cctaaataaa aatcaaaaac
     8941 acaatataga agttgtagta gatagaatag taattaaaga tggaatagaa tcaagactag
     9001 cagattcaat tgagactgca gttaagctat ctgatggact tgtaatagcc caaataatag
     9061 atggagaaga aattcttttt tcaactaaat ttgcatgccc agaacatggg attggtatag
     9121 aagaattatc tccaagaatg ttttccttta atgctccttt tggtgcctgt gatgtttgta
     9181 atggtcttgg ggaaagtaaa gaagttgacc cagaattagt agtaccaaat aaagatttat
     9241 caataaaaca aggtgcagtg gcagcatggg gttcaacagg tgttaatgat gacacttatt
     9301 acagtaaaat gataaaaagt ctagcagagc attttaatgt atctttgaca acaccattta
     9361 aagatttacc agatgatttt gtggaagaat tactttatgg taaagataat ataattgtag
     9421 agtttactta tgagtcaaaa tttggaggaa ctagaaatta taagtcatac tttgaaggtg
     9481 taatagtaaa cttagagaga agatatagag aaactaattc agattacatg agagataaga
     9541 ttgaagaata tatggctgaa agaccatgtc caaagtgtaa aggtatgaga cttaaaaagg
     9601 aagttttatc tgttttagtt gatggaaaaa atataatgga agttacaaac ttatctgtaa
     9661 atgaattaat cgactttatg gaaaacataa atcttacaga aaaacagaga tttatagctc
     9721 atgagattat aaaagagata aaaggaagag ccatgttctt aagagatgta ggtctcgatt
     9781 atttaaattt atcaagaaaa gctggaactt tatcaggagg agaagcacaa cgtataagat
     9841 tagcgactca aataggttct gcattagttg gagtcttata tgtacttgat gagccaagta
     9901 taggacttca tcaaagagat aatgataggc ttatagccac tcttagacat ctaacagact
     9961 taggaaatac cttaatcgtt gtagagcatg atgaagacac aatgagagaa gctgattatg
    10021 ttatagacat tggtccaggt gcagggatac atggtggtga aatagttgca cagggtactt
    10081 tggatgaaat aattgaaaat gagaactcaa taacaggtca gtatttaagt ggtaaaaaac
    10141 aaatattgct tcctgagact actagagaag gaaatggaag ttttatagaa atagttaaag
    10201 catcagaaaa taatctgaaa aatattgatg taaagttccc attaggtaag tttacatgca
    10261 taacaggtgt ttcaggttct ggaaaaagta cactaataaa cgatatactt tacaaaggtg
    10321 ttgcaagtaa agtgaataga ctcaagcaaa gagctggtaa gcataaagag ataaaaggaa
    10381 ttgaaagtat agataaagtt ataaatatag accaaagtcc tattggaaga acacctcgtt
    10441 caaatcctgc tacttataca ggtgtatttg attttataag agatattttt gcagctacta
    10501 atgaagccaa agcaagaggt tataaaaaag gtagatttag ttttaatgta aaaggtggta
    10561 gatgtgaagc ttgtaagggt gatggaataa taaaaataga aatgcatttc ttaccagatg
    10621 tatatgttcc ttgtgaaatt tgtaaaggtg aaagatacaa tagagaaaca ttgcaagtaa
    10681 aatacaaaga taaaactata tctgatatat tggatatgaa tgtggaagaa gctgttgagt
    10741 ttttcgaaaa tataccaaat ataaaaagaa aattagaaac tttaatggat gtaggacttt
    10801 catatattaa gttaggacag ccttcaactc aattatcagg aggagaagca caacgtataa
    10861 aattagctgc tgaacttagt aaaagaccaa caggaaagac tttgtatata ttagatgaac
    10921 ccactactgg acttcatatg gcagatgtag acaagctaat ccaagtattg caaagactag
    10981 cagatacagg aaatacgatt atagtcatag agcataatct agatgttata aagacttgtg
    11041 actatgtaat agatttagga ccagaaggtg gagataaagg tggaactata gttgcaactg
    11101 gaacaccaag agaagtatct aaagttgatg gttcttatac aggtcaattc ttaaaaaaat
    11161 atttttctta agtcatataa attgtgaaaa attttagagc tagatatata cgctaaactg
    11221 ctcttttata agtaaattag taaaataaaa gttgtaaata gtaatacaaa gtaaagtcca
    11281 tattactctt cattgttaaa tttgtttttt aaatcaattg tagaagggaa tatggacttt
    11341 aacttgtcta aagtactgga aattgtataa ctttttaaat ttcatatttt agggtataat
    11401 tttagtataa aatttaatgt tttggagggc gagatgtttg atatacaaga gcatttaaaa
    11461 aaattacctt ctgagcccgg agtatattta atgaaagaca aatacgacca tataatatat
    11521 gtgggaaaag ccatatctct aaaaaatagg gtaaggcagt attttcaatc ttcaaaaaac
    11581 catacatcta aagtaaaatc tatggttaag aatatatata agtttgagta tattataacg
    11641 gattcagagt tagaggcatt aatacttgaa tgtaatttaa taaaaagata cagaccaaag
    11701 tataatgtag tgcttagaga tgataaaact tatccatata taaaagtaac tacaaatgaa
    11761 gactatccaa gaattttaaa agttagaaga gttcttaaag ataaggcaaa gtattttgga
    11821 ccctatacca atataactgc tgtgaatgat actttggagc ttataagtag tacttatcca
    11881 ataagaagct gtaaaattga tatagataaa gcaataaaga ataagacaag accttgttta
    11941 aatctacaca taaataaatg tttaggacct tgtacaggaa atgtttctaa agaagagtat
    12001 ggaaaaatga tagaagagat tataatgtgt ctatctggca aagaagaaaa attgatggag
    12061 cttttaaagg aaaaaatgaa tgagagttct atgaacttta gatttgaaga ggctgctgta
    12121 tatagagata agataaagag ccttgaagag atgatacaga aacaaaaaat agatgctact
    12181 gtaagtgact taaatcaaga tgtggttgca atggcaagag ctcataatga agcttgtgtc
    12241 caggtatttt tcataagaaa tggtaaaatt gtaggcaggg aacattttat attagaaggt
    12301 gtaatggata gtccaagggc ttctatatta agttcatttg taaaacaatt ttataatgaa
    12361 caagagtata tacccaaaga gttaattata gaagatgaga tagaagatag ttgtatatta
    12421 gaagaatggc tgtcatctaa aaaggggcaa aaagtaacaa taagagttcc tcaaaaggga
    12481 gagaagaaaa gcttagttga aatggttagg aaaaatgctg tagagtatct tgaaaaattt
    12541 tctgatatga ataaaagaaa atatgaaaaa agtattggag cattggaaga attaaagcaa
    12601 atattaaatt tagaaaaatt gccaataaga atagaagctt atgatatatc aaatatacaa
    12661 ggtgtagatt caattggttc tatggtagtg tacacgaatg ctaaaaaaga taagaaggaa
    12721 tataggagat ataaaataaa gacagttatt ggacctaatg attatgattc tatggctgag
    12781 attgtagata gaagattaaa acatggaaat ttacctgact tgatattatt ggatggtgga
    12841 aaaggacaag ttagtgcagt aaaaaaagta ctagaactta atgatgtaga tatacctctt
    12901 tggggaatgt acaaagatga taagcataga actaaaggat tgatatgcaa agaaaaagaa
    12961 atagagctag acaaaacaac taatttatat agatttattg ctagtataca agaagaagtt
    13021 cataattatg caataacata tcatagaagt ctaagaaata aagctttgac aaaatctatc
    13081 ttagatgata tacaaggaat aggtgaaaaa agaaagaaat cattattaaa tcactttaaa
    13141 gatgtagatg ctataaaaaa agctactatg gaagaacttt tagaagtaga tggaatgaat
    13201 aaaagcattg cagataatgt ttataatttt tttagaaagg aagcaaatta atggaaacta
    13261 gcaataaagt atcaataaga gagataataa aagagttgaa gttaaaagtg gtatacatgc
    13321 ctgatgatgt agattattat gtctactctc aagatataaa tagaccagga ttacagtttg
    13381 caggatattt tgattatttt gcatatgaaa gaatacaaat agttggaaag acagaatata
    13441 atttttttgg actaatggat agtcatattc gagaagaagt actagataga tttttctcat
    13501 atgaaatacc agcgttaata atttctaggg acttggaaat taagccagat gtaattgaaa
    13561 aggctaaaaa atataaaaga atacttttga gcacaaatag aaatactact agacttataa
    13621 atagactgtc aaattatttg gataataagt tagcaccaca cacaacaatt cacggagtgc
    13681 tagtagatat ttatggtata ggtgtactga taaaaggtga aagtagtata ggaaagtcag
    13741 aaacagcatt agaattgatt caaaggggta atagattagt tgcagatgat gctgtagaaa
    13801 taagaaaatt agatgaaagt atgcttgtgg gtcagtcacc tgaattgata aggcattttc
    13861 ttgagataag aggaataggg ataatagatg ttagaagctt atatggagta ggggcaatca
    13921 aaaattctaa aatgatagat ttagtagttc atttagaagc ttgggatgaa actaagtact
    13981 atgatagact tgggctggat aaagaatatg aagaaatact tggtgttaat gtagagaaat
    14041 tggttgtacc tgttaaacct ggaagaaata ctgctatgat attagaagta gcagcaatga
    14101 attttagaca aagaggaatg ggatacgacg cagctcaaga atttactaaa aaattatcaa
    14161 aactaattga tactaagtag tactgaataa taatgaacta aacatcattt aattaaatat
    14221 tgattaggat tatgtcctac accttataaa ttaaagtcaa gttgtatata tataatgttt
    14281 attaataaga tatattatat aaggataatt taaagtacag cgttagatta taataatact
    14341 agattaattt tatatttgaa tttcattata taacaagaaa gttggaattt tttatgggaa
    14401 tagaatattt tagtaaactt ttagaaagta gtactgaaaa agaattgctc ttaagtaaaa
    14461 agtcaaataa cataagtaca gcaagattaa tatctttttt gatagtgata gcagggtttg
    14521 ctattggatt ttacaataaa aatatagtag gtatttttgt tggagttgta tcaataataa
    14581 tatttatagc actcttagtt attcatagta aagtaaaaga agaagaaaca tattttaaaa
    14641 gtaagagcga agtattaaat aagtatatta agagatttgg agatggttgg aaggaattta
    14701 aaatagatgg taaagaatac ttaaaagatg aaaactcgca agcaaaagat ttagacttat
    14761 ttggaagagc atcattgtat caatatatct gtgtagctaa tacatcttat gggaaaaatt
    14821 ttttagccaa atatttgtgg aatgaaaatc cagatgagaa tgtaatcata gaaagacaga
    14881 tggctataaa agaactttta tcaaaagatg atttttctat tcatattcaa acactcagta
    14941 atataatcgg taaagagcaa aaaagcaatt cagatagtag tatagaatcg tttatagagt
    15001 atggagaaaa taagaatgtg tatataccaa aatggatgca tatttttact tggggtttac
    15061 caactgcgat aattttatct tttatatttt gtgtgttagg atttttacct gttttacctg
    15121 tttttttact ttttataatc cagttagggt ttagtggctt tggatatcca aaacttatgc
    15181 aaactctttc tccattattt tcatttagta gaagtataca agtatatgaa aaaatgtttg
    15241 aggttttaga aaaagagacg tttgagagtg tatatttgaa agaattacaa gacaaactct
    15301 ctaagggaag tggagtttca agaggtgtta aacaattaaa ttcaatagga aatgccgtaa
    15361 acctaaggta taatcagata atatatataa ttgcttgtgg tgttttgatg tggaactatc
    15421 attgtgcaga agctttggag cgatggaaag gtgtatatgg aaatcaaatt agagattggt
    15481 ttgaatctat tggggaattt gaagctctaa taagtttaac agttatttct catgtgaagg
    15541 aaaatacatg ctttccagta ataaaatatg aagatactcc aagattgaaa gttgaagaag
    15601 tatatcaccc attaatagca gaaaaaagtg taatagcaaa ttcaatacaa ttaaattctc
    15661 agacttgtat tatcacaggt tcaaatatgt ctggaaaaac aacattttta agaagtatag
    15721 gtgtaaactt agtgctggca tatgcaggtg ctccagtatg tgctaagagc tttgatgcaa
    15781 cctgtatggc tatatttacc tctatgagaa tacaagatga tgtaagtcaa ggaatatcaa
    15841 ctttctatgc tgagattctt agaataaaat caatgattca atatagttta aaagaactgc
    15901 caatgttggt tctagtagat gaaattttta agggaactaa ctctgctgat aggattattg
    15961 gagcaagtga ggcagtaaag aaattatcaa gaccatgggt tataagtatg gtgacaacac
    16021 atgactttga gctatgtgac ctttcaggga atggagatgt tgaagttgta aactatcatt
    16081 tctcagagta ctatgtagac gataaaattc attttgacta taagataaaa tatggaagat
    16141 gtaaaactac aaatgcaaaa caacttatga gaatggcagg gattctttaa ttaataaata
    16201 ggctaattaa taaatacatc tatttagaaa cataatttaa tttatgaaat taataaggat
    16261 tgtcttaaat tacataaaag tattttaaga caatcctttt ttaagaataa attttatact
    16321 ttgttaagac tacttagctt cttcacaagc acattcttgt ggacactctc cataaataca
    16381 actcttatca aagtaatgag tatgaaggta tttatgagct acatcactat ttggttctcc
    16441 aaagaagtct ttataaatag cttgtaaatc aggattttca tgagatttac gaatagcctt
    16501 atttctatct atttcatata acgcatttgc acgtctatca actatttcag tattaccatg
    16561 gtgataaggt tgaccagcac ctccaacaca tccaccagga cacgccatga cttctatgat
    16621 atggtattta cattctccac ttctaacctt atccataatc tttctagcat ttttaagtgt
    16681 atttacaata catacattaa ctgtagttcc atcaacatct atacttgctt ctctaattcc
    16741 tttaagacct ctaacattag tgaagtttac attatctaaa gtcttattag ttatcttctc
    16801 atatgaagta cgtagggcag cttctaaaac tccaccactt gctccaaata tagatgcagc
    16861 acctgtagat tttcctagag gattatcaaa atcttggtct tgaagattag gtaaatctat
    16921 agcagcttct tttatcatct tagctaactc tctagtagtt atagaaaggt caacatctag
    16981 tattccagat tcacttaatt cttctcttga agcttcatat tttttagcta cacaaggcat
    17041 tacagataca acataaagtt cctcaggatt gattcctaat attttaggtg catagtagtt
    17101 tttagctata gaaccaaaca taccttgagg agatttacag ctagatgcta agtttaactt
    17161 gtctggataa ttgtgttcta agaagtttac ccatgcagga caacagcttg ttaatatagg
    17221 aagattttca cctttttgga ttctttctat aaactcagta gcttcttcca ttatagtaaa
    17281 gtctgcacca aagtttgtat caaatacatg ttcaaatcca agtgctttta aagcagctac
    17341 catttttcct gtagagattg accctggttc taatccaaac tcttcaccaa tagcaaccct
    17401 tacagcagga gcaacttgca ctactatagt cttttctttt ttatttaaaa catcccaaag
    17461 tttaggtaca ttatccactt ctgttaatgc tccagttgga cagacagata tacattgacc
    17521 acagaatgta cactctgttt caaccatatc agagttaaag aatgtactaa ctagagtatt
    17581 aaatccacga ttaactccag ataatgctcc tactgtttgt atgtcattac atacagtctc
    17641 acatcttcta cataatatac acttagaatg gtctttaact aaagatttag tagaagtatc
    17701 tttacctgca aaagatttag aaccttgata tcttattttt cttactccta aatcagcagc
    17761 tatagtctgt aattcacaat ctccattttt ttcacataca aagcaatctt gtggatggtc
    17821 tgatagtaat aattcaacaa tagttctacg agcatttaat gcttttgcac tattagtctg
    17881 aactttcata ccttccttta taactgttcc acaagctgga actaatcctc tctctgtctc
    17941 aaccatacaa acacgacaag aagcacaagt atcaagctta tctatttcat tcatatgcaa
    18001 atgacaaagg ttgtgtattt ttatatttat taattttgca gcatctaaga tagaagttcc
    18061 actaggtgct gaaacgtgtt tgccattaat agttaaatta actaaactca ttgttattcc
    18121 tcctccaaat aagttatttc ttgattatag cgttaaatgt acaattatct atacaagcac
    18181 cacattttag acacttagaa gtatctattg tatgttgttc tttaacagaa cctgttatac
    18241 aaccagcagg acacactcta gaacattttg tacaaccctt acagtcatct gttataaagt
    18301 aagaaagtaa gttctgacat ttaccagcag gacatttctt atctacaaca tgagctatat
    18361 actcatcttt gaaatattga agagtactta aaacagggtt tggagcagct ttaccaagac
    18421 cacataatga agcagtttgt atagtttcag caaggttttc taggtcatct aaatcttgta
    18481 gagtaccatt accttctgta attttagtta atatttctaa caatcttgta gtacctatac
    18541 gacaaggtgt acatttacca caagattcct caacagtaaa ctcaaggaag aatttggcta
    18601 tatctaccat acagtcagat tcatcaagaa caagcatacc accagagccc atcattgaac
    18661 cgatagaact taatgaacca aagtctatag gagtatctaa atgttcagtt ggtatacatc
    18721 caccagatgg gccacctgtt tgaacagcct taaatttctt accttcaggg attccaccac
    18781 caatttcaaa tacaatatct cttaaagtag tacccattgg aacttcaaca agccctacat
    18841 tttctacttt tccaccaaga gcaaaaactt tagtaccact agaatcttca gtacctaagt
    18901 tggcaaacca atctccacct ttaagtatta ttgcaggtat attagcaaaa gtctcaacgt
    18961 tatttaagca agtaggagat ttccatagac cactcttaga agaactataa gtcttcattc
    19021 taggttcacc acgtctacct tcaattgaat gcattagagc tgtaccttca ccacaaacga
    19081 aagcacctgc accatatttt aattctaatt taaagttaaa tccagtacct aagatatttt
    19141 caccaagtaa accgtatttt tcagcttgag ctatagctac ttttaatctt tctatagatt
    19201 ttggatattc tgctcttata tatatgtatc ctgtatcaga acctatagca tatccacata
    19261 ttgccatagc ttctagtaca ctatgagggt caccttcaag tacagatcta tccataaatg
    19321 cacctgggtc accttcatca gcattacata caacaaactt tttatctgtt ggaccagctg
    19381 gattttttga agcagcttcc catttagagc ctgtagggaa accagcacca cctctaccac
    19441 gaaggccaga agtttttacc tctgcaataa cttcctgagg agtaagagaa gttaaacatt
    19501 tgcctagagc taaataacca tcattggcaa tatattcttc tatactatct gggtctataa
    19561 gaccacaatt ttttaaagct atacgtaact gttttttgta gaaagacatt tcttcttgtt
    19621 cttctacttt tttacttaaa gattcttcct catataataa ttcctcgaca actgtatttc
    19681 taattaagtg gctttgaact atcttttcag catcagatgg ctcaactttt acgtagaaaa
    19741 cgttatcagg ataaactttt acgataggac cttgagcaca gaaaccaaaa caacctgtca
    19801 aacgaacact aactttatct tggattcctg atttttttat ttcattttct aattcactaa
    19861 ctatttctag actgtttgaa gatgtacatc cagtatcaca acaaacaagt aattctcttc
    19921 ttagtacatt ttccttagaa taattttttc ttaagctaag attaggtttc agctcatcag
    19981 ctaaaacttt taattcatca aatgaattta ctttacgcat tatttattca cccctcttaa
    20041 caattcaatt ctaattctct ataagtatct aatatttcgc ttacttggtc aggtttcact
    20101 ttaccataaa ctttgccatt tacagtaaca actggagcta aaccacatgc ccccaaacat
    20161 cttaaacctt ctaaagaaaa tttaaaatca ctagtagttt ctccaacttt tatgccaagc
    20221 tgtttttcaa aagcacttaa gattttgtca gcacctttta caaaacatac agtccctaga
    20281 cagacactga ttttatactt acctacaggt tctgtagtaa aataagaata gaatgtaaca
    20341 accccatata cctttgcagg agctactcca agttttctag caacatgaag ttgaacttct
    20401 tttggaagat acccaaatat accttgggct tcatgtagaa cttgtattaa cgcaccttcc
    20461 tttgttgcaa gagagtcaat aaatatatct agttcgtcaa ataattgctt gttgtgtgaa
    20521 ataaaatcgc acataacaaa tccccctttt ctttttaaag ttattatttt tcaaaaaata
    20581 attaaccatg agttgacccc aacattatgt gggtgaacaa aaccaaaaca ataaagaaag
    20641 aataatatac aacaatttct ttatttataa aaacaatgca aaaaagttac ctattaaaaa
    20701 taaaaactat actagtctat tataatataa aataattcag aatagttaaa aaaaataaaa
    20761 aaaatgagct aaattcaata aaaaaaaaat aatatatata aaaaacttta aaaaataaac
    20821 caaaatgtaa aatttttata aaataaaaga tttataaaac tgctgataat agtcttgaaa
    20881 ttgattcctt gatttttata taagtagacc tagaattata tatatctaat gttatttcct
    20941 ttgaatttaa aatatcattt tcaaatataa ttctttgttc caatgctttt tttgaagagt
    21001 acataaatgc attcacttcg aaattaagct caaaacttct gatatccata ttagctgttc
    21061 ctatagagca tatagagtca tctataacta ttgtcttagc atgtaaaaat gcgttttgac
    21121 cataagtgta gattttagct ccaaacttta aaagctcccc agcatatgaa tatgatgccc
    21181 agtatacaaa tggatggtca ggtttagaag gaatcataac tctcacatca acaccagata
    21241 aacaagctat ttttaaagta tctataaaag ttgagtcaag tattaaataa ggactctgta
    21301 tgtatatata ctttctagct ttctgaatca ttttaaggta accatattta atctcatcaa
    21361 gttctgatat atctggacca cttgatacta tctgaatccc aatattttca gaaggatgat
    21421 tagaatttgt atcttcttct ataaagtact tttctaaatc taaatcttct ttagttgtgt
    21481 atctccaatc gaggatgaat ctcatattta ggtcaattac acaatcacca gtaagcttag
    21541 tatgtgtatc tctccataga ccaaattttg gatttctacc taaatattca tcaccaacat
    21601 tatatccacc tacaaatccc accttaccat caatgacaac aatttttcgg tgatttctat
    21661 agtttaagtt aaaatttaca attttcaaga atgatgggaa gaagcttcca attttaacgc
    21721 cactttcttt aagtctggaa agtgtactat tttttagtgt tctaccgcca actgcgtcaa
    21781 ataaaagtct tacttcaaca ccttctttag ctttgtctat aagaatgtct attatttcag
    21841 ttcctatttt gtcatctttg aaaatgtaaa attgtatgtt tatatatttt ttagcttttt
    21901 taagttcttc aagaagactg ttaaaaaatt gactagattc agcataaatc cacacatcgt
    21961 tattattggt ataatgagca ttatttgaat tagccaatgc ataaatcata tccttatgtt
    22021 gatgtatatc tgaatcaatt tcagatgtag attggagttt aacctgagta tctagtatat
    22081 tgcttttgat tatcttatca tccttttctt tcaatctaaa catgttgttt tttgaaatat
    22141 ttctaccaaa agctatataa agtatgaatc caagagcagg aatcaatact aatataagaa
    22201 gccatgttaa agttgtattt atgtttcttt tttctctaaa gataaggttt agtataacca
    22261 tgaaattaat tatatatatt gtagtaactg ctatttcata tattgacatt tcgaaaaatg
    22321 atatatcaaa cataaaattt cctcctttaa a
//
LOCUS       DBGJFK010000060        22284 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.060, whole genome shotgun sequence.
ACCESSION   DBGJFK010000060 DBGJFK010000000
VERSION     DBGJFK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22284
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.060"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            93..428
                     /locus_tag="ACOIAP_002662"
     CDS             93..428
                     /locus_tag="ACOIAP_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGZ2639542.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQRDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNIVESTYFLSESGLLLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            565..1842
                     /locus_tag="ACOIAP_002663"
     CDS             565..1842
                     /locus_tag="ACOIAP_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein/redoxin"
                     /protein_id="HGZ2639543.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMRAITAFLLGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNMSQNSKIESKQEENKRENSTNKEERSEGNDSQKDSNNENNDEG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPHIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1963..3351
                     /locus_tag="ACOIAP_002664"
     CDS             1963..3351
                     /locus_tag="ACOIAP_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGZ2639544.1"
                     /translation="MKKIFDAIIIGFGKGGKTLAGNLANRGLKVALIEKSNKMYGGTC
                     INVACIPTKSLENSANNVKTKNINSWDEVQVEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENKIYELVADNIFINTGSRPFIPNIKGIENKNVVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGTEVTILNSNNGILPNEDVEDSEEI
                     IKLLEKRNVKIINNANIKEIKEVSKLAIVEYEVDGKSKELASNIILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIIINQLFGD
                     KTRTTSDRKNIPNSIFISPAFSRVGLNVKQAKEKGYKVLVANMPIEAIPRAKQIGKTD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPSMIKEV"
     gene            3795..4433
                     /locus_tag="ACOIAP_002665"
     CDS             3795..4433
                     /locus_tag="ACOIAP_002665"
                     /inference="COORDINATES: protein motif:HMM:NF037435.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HGZ2639545.1"
                     /translation="MKAKEEIEWLLNRDYKIDPIVNFVGDRYQFSIRQRDALKRAVCT
                     DEKNIIRQSKRLSLDKIKENTVNIDGFNLIISIEVALSGGTLVIGSDGNIRDLAGLRG
                     TYKIINKTEEALNLIGKFFNKYNAQNLKFYLDAPVSNSGNLKYRILEHAKTWGIETEV
                     ELVKNADVVLEKLDRVVSSDAVIVDKCISYFNVARGIIEEYIKDCNIVNLNK"
     gene            4549..5418
                     /locus_tag="ACOIAP_002666"
     CDS             4549..5418
                     /locus_tag="ACOIAP_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HGZ2639546.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDNKTGYVFNYFLSTDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPDTPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5599..6744)
                     /locus_tag="ACOIAP_002667"
     CDS             complement(5599..6744)
                     /locus_tag="ACOIAP_002667"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGZ2639547.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKNSIKSLGTKKAFVVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYNEVKQNPTVTNVNKGLEILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIVAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDNNSLSTITVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSSPSKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENAMKDACAGANPVFFDKKKIIELFMKIS"
     gene            complement(7076..7852)
                     /locus_tag="ACOIAP_002668"
     CDS             complement(7076..7852)
                     /locus_tag="ACOIAP_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HGZ2639548.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADAINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPE
                     GLKGFTEKSITDFDVLYDQLLEIQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8442..9416
                     /locus_tag="ACOIAP_002669"
     CDS             8442..9416
                     /locus_tag="ACOIAP_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HGZ2639549.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9514..9819
                     /locus_tag="ACOIAP_002670"
     CDS             9514..9819
                     /locus_tag="ACOIAP_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HGZ2639550.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTIKTITALDDI
                     TIYHKLAIKDIAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9974..11134
                     /locus_tag="ACOIAP_002671"
     CDS             9974..11134
                     /locus_tag="ACOIAP_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HGZ2639551.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQINKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            11184..12086
                     /locus_tag="ACOIAP_002672"
     CDS             11184..12086
                     /locus_tag="ACOIAP_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HGZ2639552.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNISSEDIIKLKTIINESTFYNYDVFKRERCTIHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDNSFEDPQKTVYFTKRVIKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSSVPFPIK
                     LKVCSRVNGEERQSSNTRLFISDVSDIVSELSKGMTLESGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            12166..13059
                     /locus_tag="ACOIAP_002673"
     CDS             12166..13059
                     /locus_tag="ACOIAP_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGZ2639553.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDREGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVDKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKAEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMDKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      13112..13293
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13523..14653
                     /locus_tag="ACOIAP_002674"
     CDS             13523..14653
                     /locus_tag="ACOIAP_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2639554.1"
                     /translation="MKLKSNVLKQFFLIILAIVMVGGLIGCSKNDKENKQVSNGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDIA
                     TSELNKTVQKIEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14725..15750
                     /locus_tag="ACOIAP_002675"
     CDS             14725..15750
                     /locus_tag="ACOIAP_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGZ2639555.1"
                     /translation="MDFINKMRIRNTTIFIVLIISIILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGSCLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVRNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILITVGVLGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIKFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQVS
                     KLIFKTSDNRILIPVVIFLGSIVTALCDLISRVVLSPVELPISTITSLLGAPIVVMLL
                     MKRKDRA"
     gene            15753..16949
                     /locus_tag="ACOIAP_002676"
     CDS             15753..16949
                     /locus_tag="ACOIAP_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639556.1"
                     /translation="MLKTNNLSVGYNNKVVVSDINIEVKSGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINHISRKALSKKMALVLTNRLLADLMTVQDIVNIGRYP
                     YTGFFGNLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKNLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDENIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFESISDESFDLAIRNLNASKIIIDT
                     GFSVGETNKRNIDIVKEALKLDKKVYSFRNRDESKKYYDSLDNKIEHVDKVSQIVDSI
                     NMNNLL"
     gene            complement(17159..17884)
                     /locus_tag="ACOIAP_002677"
     CDS             complement(17159..17884)
                     /locus_tag="ACOIAP_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGZ2639557.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNTGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGANFRFCDLS
                     NSDIRGANLENSNLEYATLNGVISDKSTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAKDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            18362..20461
                     /gene="nrdE"
                     /locus_tag="ACOIAP_002678"
     CDS             18362..20461
                     /gene="nrdE"
                     /locus_tag="ACOIAP_002678"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGZ2639558.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDREALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSMDFIKNIYEIIDKQKFEFQSYMSANKFYQNYALK
                     SNDGKKILETYNDKVLIVALTLGNGNKDLVLNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMNKWYDKLVNDNDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDIGIIKMSNLCCEIFQYQTHSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIEKNQT
                     FEGFDKSEYAKGRNSKVLSKYYEQSYLPKSEKVKALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAIAPTQSISYVQNSTSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNILYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            20474..21445
                     /gene="nrdF"
                     /locus_tag="ACOIAP_002679"
     CDS             20474..21445
                     /gene="nrdF"
                     /locus_tag="ACOIAP_002679"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGZ2639559.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKIWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNSEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEILEEKMYSILYRLMENEIEYTNIIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            21522..22148
                     /locus_tag="ACOIAP_002680"
     CDS             21522..22148
                     /locus_tag="ACOIAP_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGZ2639560.1"
                     /translation="MKYEWRKRDKELYLPKKNPAIIEVPEQKFIMLKGNGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKCLDVLIKEDLIYT
                     LMIHQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYIHHEIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         8640 a         2437 c         3908 g         7299 t
ORIGIN      
        1 attaaataaa gctaggtata tttataatat taataaatat attgctataa aagtttgttt
       61 aataaattaa ataaggaaaa gaggagaata aaatgtacaa catagatgat atgatatata
      121 attgtccagt agaagcttta tcaaatattt taggtaaaaa atgggtggct ataattatat
      181 ggaaaataca aagagataaa aaacgatttg gagagttaca aagagctata ccagactgta
      241 gtaagaaaat gttagttcaa caactagatt ttttaattga acagggtatt atagtcaacc
      301 aaaaaaagtt ggttaataat attgtagaat caacatattt tttaagtgaa tcaggattac
      361 tattacttcc tgtcatggaa aaaatgatta tgtggagcaa taaaaattta aattgtgata
      421 aatactaaaa tttactctgg aagtagtgaa gagttaatta aattataagt agaaaaatgt
      481 attgaaatta cataattttt tagtcagatt ttaatttaga aatgagattg tactattgga
      541 aataaaataa ggaggaattt taatttgcaa aatgtaaatt tatttttagt gtttatagaa
      601 gggatagtat cattcttttc accatgtata ttgccaattt tgcctattta tttgagcata
      661 ttgtcaaata gtagtgtaga gaatttgaaa gaaggaaaga cgagttttat aggaagttct
      721 ttatttaaaa atactatatt ttttgctctt ggaatctcga caacattttt tatattgggt
      781 tcatcagtaa aagtattgag tatgtttttt aatgaaaata aagatttaat aatgtttatt
      841 ggtgggatta taattattat tatgggatta ttttacatgg gaataattaa atcttcaata
      901 ttgaatagag aaaaaagatt taatgttaag tttaaagaga tgagagcaat aacagctttc
      961 ctgttaggtt ttacatttag ttttggatgg acaccttgta ttggtccaat attggcatct
     1021 gtattagtaa tggtttcaag ttcaagtaat catcttagtg caaatctttt aatagcagta
     1081 tataccattg gatttatttt gccattcata attacagcta tgttttacag taaactattt
     1141 aaaactatag ataagataaa atctaatatg gaaattatta aaaaaatagg tgggattata
     1201 cttatagtat caggaatatt aatgatggta aatggatttg gaagtataag caaacacttt
     1261 aatatgtcac aaaatagcaa aattgaaagt aagcaagaag agaataagag agaaaattct
     1321 actaataaag aagaacgttc tgagggtaat gatagtcaaa aagactctaa taatgaaaat
     1381 aatgatgaag ggtctaatga tgaagataga ataaagtcta ttgattttac tttaacagac
     1441 cagtatggta aaacacataa attaagtgat tatgaaggca aagttgtatt cttaaatttc
     1501 tgggctacat ggtgtcctcc atgtaaagaa gaaatgcctc atatagaaca gctgtataaa
     1561 gactataata aaaataatga tgatgtagta attttaggag tagcttcacc taatttaggt
     1621 agagaaggtt caagggaaca tgtagttaac ttcttaaaag accaaggtta taccttccct
     1681 gttgtgcttg atgaagatgg agcattagca tatcaatatg gaattaatgc ttttccaact
     1741 acatttataa ttgacaagga aggatatgta actcagtata ttccaggagc tatggataag
     1801 gcaactatgg catcctttat tgaaaaccag agaaataaat aaaagtattt aagtagaagt
     1861 ttataaatca gtttaaggtt acaaaaaagt gcctaattgt actacttagg taatcttgtt
     1921 atagtaaaag tataaacaat acaagaaagg attgaaattt atatgaaaaa aatatttgat
     1981 gctataataa taggatttgg aaaaggtgga aaaacattag caggaaattt agcaaataga
     2041 ggattaaaag tagctttaat agaaaagtca aacaagatgt atggtggaac atgtataaat
     2101 gtagcatgta taccaacaaa aagcttagaa aattcagcaa ataatgtaaa aacaaagaat
     2161 ataaattctt gggatgaagt acaagttgaa tatgagaagg ctatagataa aaaagaaacc
     2221 ttaattacaa aacttagaga agctaactat aataaattaa attcaaatga gaatgtaact
     2281 atattcacag gaatgggaac tttcattgat gaaaaaacag ttcaagttaa aactgaaaat
     2341 aaaatttatg agttagtagc agataatata tttattaata ctggttcaag accatttata
     2401 cctaatatta agggaattga aaataagaat gtagtatatg atagtgagtc tcttatgaat
     2461 ctaagaactt tacctaaaaa aatgacaatt ataggagctg gatttatagg tttagagttc
     2521 gcaggtattt atagttcatt tggaacagaa gttacaatat taaactctaa taatggcatt
     2581 ttaccaaatg aagatgttga ggattcagaa gaaataataa aattactcga aaagagaaat
     2641 gtaaaaatta taaataatgc aaatataaaa gagattaaag aagtttctaa attagccata
     2701 gtggaatatg aagtagatgg taaatctaaa gaattagcaa gtaatataat acttgtagct
     2761 acaggaagaa aggcaaatac tgaagggtta ggactagaaa atgcaggtat agaattaaat
     2821 gaaagaggat ttattaaagt gtcagaaact cttaagacta ataaagagca tatatgggct
     2881 ataggagata taaatggagg tccacaattt acttatattt cattggatga ttatcgcata
     2941 attattaatc agttatttgg agataagact agaacaacta gtgatagaaa gaatatacca
     3001 aattctatat ttataagtcc agcattttca agagttggtc ttaatgttaa acaagctaag
     3061 gaaaaaggat ataaagtatt agtagcaaat atgccaattg aagcaattcc aagagctaaa
     3121 cagattggca agacggatgg gtttataaaa atagtgatag ataaaaaatc caataagata
     3181 cttggagcta gtatgatatg tgaaaattca agtgagatta tccatttgat tcaattagct
     3241 gtggatttag aagtagagta tacatactta agagaccgtg tttatgcaca tccaactatg
     3301 acagaagctc ttaatgatat tctatctcct agtatgataa aagaagtata atataagttt
     3361 aatatataaa gcttaaaatt atcattataa atagatttta gaaagagact atctcaaaat
     3421 agagataagt ctctttttta ctgtttaaat gataaaaata tatttgtttt tataaaagaa
     3481 gattacgtta tgaactaaaa atttattttg aaacactaat tatttatgtt ataaagttat
     3541 aaatataata tagaatctat tattttgtat tattaagtgg agttaagcgt tataattaat
     3601 tataaatatt gaataaccta aatggataag ataatggtat taaaaattat cctaaaaggt
     3661 gaaataatct gtatttaata tagcatagtt agatatttaa agtaaggtgg tgaaatgata
     3721 taaataagat ttctaaaaga gggtttgatg atagtgataa aagatggttt tcaagtaaag
     3781 aattaataag acttataaag gctaaagaag aaatagaatg gttattaaat agagattaca
     3841 aaatagaccc aatcgttaat tttgttggtg atagatacca gttttctata agacaaagag
     3901 atgcattaaa aagggcagtc tgtactgatg aaaaaaatat tataagacaa tcaaagaggc
     3961 tttctttaga taaaatcaaa gaaaataccg taaatataga tggctttaat ttaataatat
     4021 ccatagaggt agcattatct ggtggtactc tagtaatagg aagtgatggc aatataagag
     4081 atttagcagg tcttagggga acctataaga ttataaataa aacagaagaa gctttgaatc
     4141 tgataggtaa attttttaat aaatacaatg cacagaatct taaattttat ttagatgctc
     4201 cagtttctaa ttcaggaaat ttaaagtata ggatattaga gcatgcaaaa acttggggga
     4261 ttgaaactga agtagaatta gtaaaaaatg cagatgttgt attggaaaaa ttagatagag
     4321 tagttagtag tgatgcagtt atagttgata agtgtataag ttattttaat gtggctagag
     4381 gtataattga agagtatatt aaagactgca atatcgtaaa tttaaataag tagataaata
     4441 gaaatgagaa tataagtata tatagcaata ttattagtaa tacaagtaaa gtttgaaaat
     4501 aggagaacga atacatatcg aatttcataa aatgttgtaa aaagacatat gagaggatgg
     4561 atatgtgtga aattaactaa actaaatatt aaaaaatata gagcacctat atataaatat
     4621 gctttagcaa atgtaaattt gaggtctgct aaatctacta attcaagtat cataacagta
     4681 atacctcagg gagctaaaat ggaagtattg gatgaagaag atgactggat taaggtgatg
     4741 tataattctc aagaaggata tgtgtataag gatttggtat cagtaagcga atatgcttgg
     4801 agtaacttaa acttaagaga agataaatct acaacttcca atataattac agtaattcct
     4861 gaaaaatcta gggttgaagt ccttcaagta gatggagatt ggagtaaggt tgtatatgat
     4921 aataaaacag gatatgtttt taattatttt ttatcaactg atggaaataa accaaatgaa
     4981 ttagattata agtattttta tactgatatg attaaatttg ttaacgaaaa taatattaaa
     5041 agtactagcg attatctaat tgtaacagac cttagaaata aatatactta tatttttaag
     5101 aaagataatg gaggatgggg acaactttat aagtggcaat gtactatagg taagcctgac
     5161 actccaacta taacaggtat attttatata agtggaagaa aaccttcttt cggaacggat
     5221 gagtattcag ttaagtatgc tactagaatt aaaggtggat attactatca ttctgtacta
     5281 tatgattcaa caggaagtta tataatagat ggcagacttg gtgaagctct tagtcatgga
     5341 tgtataagat taagtacgga aaatgcaaag tggatatatg ataatatacc agatacaaca
     5401 actgttataa tccattaaga aaaaatttaa gttttttatt gagataatta tttttaaata
     5461 agtaaggcta tatattaact tctcataaag agtactattt aaaaagtgta ataagagagt
     5521 gccattaaca aaataaagac atcttgaggt actctcttat aaatatacag aattaattta
     5581 tgggatagat tgttataatt aagatatttt cataaacaat tctataattt tctttttatc
     5641 aaagaaaaca ggattagcac cagcacaagc gtctttcata gcgttttctg caagcaattc
     5701 aaaattagga ttatcaacac ctacatcttt taaagatttt gggattccaa cctcttcaga
     5761 aagagctttt atcttatcta ttacaaagtc aacacactct ttatctgatt tattatttac
     5821 atccatgcca ataacttcag ctattgggcg gaatttgcta ggggatgatt tagcattttc
     5881 ctcctcaact attggaagta gcatggcatt acatactcca tgaggtaaat catataaacc
     5941 tcctaattga tgagccatag catgtacgtt tccaagacct gcattactaa aggcaattcc
     6001 atttaaaaaa caagcataac acatttgttc tctagcttct atgtcattac catttttaac
     6061 agctcttgga agatatttaa atatctgctt tatagcatat aaggcagttg aatctgtaac
     6121 atcataagca ccattagcta ctacagcttc tatagcatga gttagtgcat ccataccagt
     6181 tgctgctgtt aaatttgatg gtttactaat cattaattct gggtcattta ctgtgattgt
     6241 agatagtgag ttgttatcaa ccattatcat ctttacatgt ctatcttcat cagttataac
     6301 gtagtttatt gtaacttcag cagatgtacc agcagtagta gttatggcta cgataggaag
     6361 acatttttta gaagttttgt tgataccttc atagtctcta atatctcctc cattagtagc
     6421 taatatagag atagctttac cacagtcttg tggagaacct cctcctatag taataacgaa
     6481 gtcgcaattt tctgatttta atatttcaag tcctttattc acgttagtta cagttggatt
     6541 ttgtttaact tcattataaa caacaaaatc cacatctatt tgagataaaa tatctgttac
     6601 tttttttacg gtaccatttg aaactagaaa tttatcacta acaacaaatg cctttttagt
     6661 tcctaatgat ttaattgaat ttttagcttc attaagacat cctttcccaa gtaaatttat
     6721 tggtggtaca taataaatgc tcataactaa aatctccttt tattttcatt gatttttatg
     6781 taaaaatata tatctaacaa ttttcactaa tttacccata atatatcgta tgttagattg
     6841 atataggttt ggtggttctt atataagaac tagattcgta attacgatta tgattagaat
     6901 ttaacatagt atttttatcg tgtcaatgaa aatataaaaa atattataaa aaaacaaagt
     6961 tactgtagtt aaatcagcaa ctttgttttt atagtataaa tcaaataaat acattagttt
     7021 aaaataaaat ttttaattat tatattttaa tatcttccgt atacagaata ttaatctaat
     7081 ttattacaat atcttcatta cgttcttcca tcatggattg aatatttttc tgagcattta
     7141 agagtaattt ttttattagt tctatttttt cgtcattagc tctaaataag ggcagtgtta
     7201 cactaacagc agctcttata catccatttt ttcttattgg tacggcaaga cattttaggt
     7261 gttccattga ttcctcgcac tctgaagcta tttgtgttct ttgaatttca agaagctggt
     7321 catataaaac atcgaaatct gtaattgatt tttctgtaaa gccttttaga ccttctggat
     7381 ataagcttat tagtttttct ttatcaaaat cacataaaag agcctttcca agacctgtac
     7441 aattagcagg tatttttttc ccaacataag aaataagtct aattggttct ggagaatcta
     7501 cttttccaat ataaagaact tcattattgt caagtatacc aagttgacaa gtttcagaac
     7561 aggaattaac tatattagtc atttcatcaa ttatatagtt aaaaatagtt cttttttcaa
     7621 aaaatgaaga ccctaatgtg taagaacgta tccctataga atatttggat gtgtttttat
     7681 caatagtaat atattttcta gcattaagtg tatgaactat aggaaagatg ctactttttg
     7741 gagcattgat agcatcggct atttctgtaa gagtatatcc attctcggat tctgctaatg
     7801 cttctaaaat atctaatatc ctagctgttg ggcgatgatt atctgaagtc ataaatttcc
     7861 cccctctttt tattagttta aagtattaga atatgttgat tttagcacac tatacgatat
     7921 tttacaatgt agaaaataaa tatgtaaatt tatatataaa taagctctta atttagatga
     7981 atatagatat ttttttaggt tgtataggaa ggagtaacta atttccaaaa tatacctaaa
     8041 gaaagcaagt gatatttagt tatataattt aagtaaatat atgtaatagt tatttttata
     8101 tataaatatc aaaatattat gaatttatat tttataattt atctattttt tagattgtat
     8161 aaaaatttta tagttttgaa taccatataa ttttaaatac tatgtatttt tgcatataag
     8221 gaagtcattt gataatacat aatgtcttat cagaaaagtt gaaaaaattt tgacaaaaat
     8281 ttattttttt tattgactca taaataggaa aatgctatca ttaattcaaa gattcgtaat
     8341 taaaaacgta gttcttaaat acgaactaaa acggccgtta gaattaaagc taaaaactta
     8401 ataagagtaa ttaaatacca tgttttagga ggattaactt tatgataatg gattttatta
     8461 aaaaaattcc tgcaggtatg atgatagtgc caatgtttat agcggctttc attaatacct
     8521 tttgcccaga tattgtacaa ataggttcgt ttacgacagc agtattttca agtgttgggt
     8581 ctgcaaccat aattggagtt caactggtat gcttgggaac tcagcttcaa tttagagaaa
     8641 tgccaaaagt tttaaaaagg ggtggtatac ttcttggttc taaatttgct ataggtgctt
     8701 tgataggtat acttatagga aagttatttg gaatggatgg agtacttggt cttacaactt
     8761 tagcagttat aagcgcagtt acaaatagta atggtagtat atatctttca ttgatgactt
     8821 catatggaga tgaaacagat tgtgcaacta tgagtttact tacattaaat gatggtccat
     8881 tttttacact gatagctctt gggacttcag gtcttgcaaa tgtacctttg ttgtcattat
     8941 tggctgcaat agtgccaata ctcgttggta tgataatagg aaattttgac aaaaaaatga
     9001 aagagttttt agaaccaggg tgtaatttac tcgtaccttt tgtaggattt gcacttggta
     9061 gtagcataaa tcttgcaagt atattaaaag gaggtttatc aggagtacta cttggattaa
     9121 tatctgtatt tgtaggaggt atatttatag tattttgtga taaatttata ggaaaacgtc
     9181 caggatatgc aggatgggct gtagctacaa ctgctggaaa tgcaattgct gtacctgctg
     9241 ctgttgcatt agttgaccca tcatggcaac catatgttgc aacagctaca acacaggtgg
     9301 cagccgcagt agttgtcact gcaatattgg tacctcttat aactagttgg tgggctaaga
     9361 agtatggatg tcctaagttc ccaaaacaaa atgaggatgg tacaataaca gcttaattta
     9421 tattacagtg agttgttggt aaaatagtaa attctttaat taggttttag gatattaata
     9481 aaattatatt atttataaag gagagcaaga ataatgataa atgcagttat aattgatgaa
     9541 aaagataatg ttgcagtagc tattgaagca atagctaaag gtagtgaaat tagttttaaa
     9601 ttaaaagaca aaacaataaa aacgattaca gcactggatg atataactat ttatcataaa
     9661 ttagctataa aagatatagc caaaggtgat aaagttacta aatatggtga acatatagga
     9721 gaagcaaatc aggaaataaa aagtggtcaa catgtgcata ttcataatgt tagaagtgtt
     9781 agagaggact tggataaaca agttatgact aatatataaa taatatttat ggatttataa
     9841 aagttgtatt cattgctttt ggtgttgaat ggttgttaaa taggatttta attgtttgat
     9901 tattgagtgt aataaaaatt ataatatatg aaaattataa aaagtatata gactatttta
     9961 ggaggaaatc agtatgaaat tttatggata taaaagacca gatggaagag ttggtataag
    10021 aaaccacata ttaatattgc ctactagtgt gtgtgcatca gatacaacta gaataatagc
    10081 atcacaagtt caaggggcag ttacctttaa taatcagaat ggatgttcac aagtacattc
    10141 agaccaacaa ttaactatgg atgttatggc tggttatgca gcaaatccaa atgtatatgg
    10201 tgtaatagtt gtatctttgg gatgcgaaaa ttgccaaaat gatttggtag ttgatgcaat
    10261 aaaagagaga acaaataagc caataaaaac tcttgtaata caagaagaac atggaacttt
    10321 aaaaactata gaaaaggctg ttcgttatgc tagagaaatg gcacaagaag cttctttgct
    10381 tagaaaagaa gaatttccaa tatctgaact tatactagga actgaatgcg gtgggtctga
    10441 cccaacaagt ggattagcag caaatccgtt gataggtgaa ttaagtgata aacttgttga
    10501 tttaggagca acatcaattt taagtgaaac tactgaattt ataggtgcag agcatatatt
    10561 agctagaaga gcagtaaatg aggaagtaaa agaaaaaata ttacatatag tacatagata
    10621 tgaaaattca ttaaaattgg taggagaaga agttagagaa ggtaatccat ctcctggaaa
    10681 tatagctggt ggtttaacaa gtttggaaga aaaatcactt ggctgtatac ataaaggtgg
    10741 tcatagacaa ataagtgaag tatatgatta tgctaaacaa attaataaga aaggtcttgt
    10801 tataatggat acacctggaa atgatgcttc atctgttgct ggtatggtag caggaggagc
    10861 acaaatagtg gtgtttagta caggaagagg aacaccatca ggaaatccaa tagctccagt
    10921 aataaaaata actggaaata aaataacctt tgcaaatatg gaagataata tggattttga
    10981 tgctagtcca gttatatacg gtccacaaac aatggaagaa ctaacagatg atttgctaaa
    11041 tatggttgta gatgtagcaa atggaaaaca atcaaaagca gaatctcttg gatatactga
    11101 aatggcaata gctagagtat gtaactatgt ataatcttta agtaagaaac taaatacata
    11161 gaattttgat aaagggtgag attatgaagt ttgtcagttt tactgaaggg gaaaatgaat
    11221 gtaaaagaac tggagttttt tctaaagatg aattatttat tatagatgtt aattctttaa
    11281 atcttagtag aaactttaaa gatttaaatg aattaattca aaatatatct agtgaagata
    11341 ttattaagtt gaaaactatt ataaatgaaa gtacattcta taattatgat gtttttaaaa
    11401 gagagagatg tactatacat gttcctatag aaaaaccaat acatgatatt ttatgtgtgg
    11461 gagtgaacta taaagaccat cttgaagaaa cacaaactca ctttgataat agttttgaag
    11521 atccacaaaa aacagtttat tttacaaaac gtgtgataaa ggcaataggt ccagaagatg
    11581 agatagatgg tcattttgag ataaataatc aactagacta tgaagttgaa cttggagtag
    11641 taataggtaa aacaggtgtt aatattagaa aagaagaggt agaagattat atctttggtt
    11701 acactgttat aaatgatatt tctgctagaa agttgcaaaa agaacatgtt caatggttta
    11761 gaggaaaagg attagataca tttacctctt taggtccatg tattttacat aaaagttcag
    11821 ttccttttcc tataaaactt aaagtatgta gtagggtaaa tggtgaggaa agacaaagtt
    11881 ctaatacaag attattcata tcagacgttt cagatatagt ttcagaactt tcaaaaggta
    11941 tgactttaga gtctggagac attatagcta ctggaacacc ttctggagta gggatgggat
    12001 tttcacctcc tcgatatatg agtagtggag atgtggttga atgtgagatt gagagtattg
    12061 gaattttaaa aaattacatt aagtaaatgt tttaatataa ttaatattaa agctaaatct
    12121 gatgtattaa tgaacatatt aaaataaatt ttaggagttt aaattatgaa agcagaattt
    12181 ttgacaccag ttgttacaat atttgatgaa gaaggaaatt tagatagaga aggtaataaa
    12241 aaagtgtacg accatcttat agatggaggt gtagatggac tagtcataat gggaagtact
    12301 ggagagttct ttaatatgtc tatggatatg caaaaagaac ttatagattt agtaactagt
    12361 catgtagata aaagagtaaa agtatttata ggtacaagtc gtatgtgtat aaatgaatct
    12421 atagaacttt caaactatgc acataatagt ggagcagatg gagttatgat aataagccct
    12481 tattatttct ctcttgatga tgatagcatt gagttatttt atagcgaaat agctaagaat
    12541 acagaagctg aaatatattt atacaattat ccagatagaa ctggttatga tttaagccca
    12601 gaacttacat taagacttgc aagaaaacat aaaaacatag ttggatataa ggatacagta
    12661 actttgatgg gacataccag agatttaata aatactatga aagcagagtt cccagaattt
    12721 aaggtttata gtggttatga tgaaaacttt atacataatc taatgtctgg aggagctggt
    12781 tgtatagggg gactatcaaa tctaattcca gaagtttgtt ccaaatgggc tgaagcttac
    12841 aataatagag atatggataa ggttatagaa attcaaaaat atattaacaa agcaatggat
    12901 ttttacttaa taaccaatcc atttatacca gcaatgaaaa aagccatgaa tattagaggg
    12961 ctacaaataa gcgattatat gactgctccg tttgtaaaac caaatgaaaa acaagtatgt
    13021 gaaattaaaa aattgatgaa tgaattaaat atatgttaaa tcgaccttgc aaagaggtca
    13081 acaataaatt acaattatct taataaaaat taaattaaaa taatactagg gtactatatt
    13141 agtttaatag ggaaagtgat gaaaatttac tacagccccc gctactgtat acggatacga
    13201 aatcaaaatc cactgaaact tataaaaatt ttgggaaggg tgatggagga aaagccgtga
    13261 gtcaggagac ctgcccagta ttatataagt tcaatttagg gtggagattg taatttataa
    13321 taaaatgaag tatcaattca ttttttgtaa agttgatata tgaacttctc cttattaaac
    13381 taggagaagt tttttatttt attaaaaggt tatacttatt aaagatgact ttaggaaaac
    13441 tataataaga tatactttaa aaagcatatc ttattatagt tttttagcca ctcataaaaa
    13501 ataagatatt ggagtgaaag agatgaaact taaatcaaat gttttaaagc agttcttttt
    13561 aattattctg gcaattgtta tggtaggagg tcttatagga tgtagtaaaa atgacaaaga
    13621 aaataaacaa gttagtaatg gtaagaaatt agaattaaaa tatgctagtg gatttagtgt
    13681 tgaagattta gaagatggaa ttaaaaaagt aactgatgga gacaatcgag aactgatttt
    13741 aataccaaag aaaattaaaa ttcctgaaaa atataaaaac gctaatatag ttagaacgcc
    13801 tgtggataat gtattaatag catccacaac acaggcttgt tctctgagaa caatagatga
    13861 actagatagt ataaaagcag taacaacaga agagcagtat tggactatta aagaaattaa
    13921 agatttaatg aaagatggga aaatacatta tgttggttca aatttagcac cagattatga
    13981 aaaaatagta gatttaaatc ctgacttaac tatagtgagt agtggcttat cagaggctga
    14041 tacaaaattt attgacaaat taaaagaatt aggtcttaat tatgttgtag acaatgagta
    14101 taaagagcaa aatccatttg gaagaatgga gtggacaagt ttaatagctg cattttatga
    14161 taaagaagat atagctacta gtgaactaaa taaaactgta caaaagatag aagaagtaag
    14221 taaaaaaata aaaaacaaag ctaaacctaa agttgtatgg gcatctgtat atgaaggaag
    14281 tgcttatata gcgcctaagg attcatatgt ggataatatg ataaaaatgg ctggtggaat
    14341 aaatgcatgt gcttcaatag attcaaatga aggacgagtg agtattgaac aattgcatga
    14401 agttgcaaag gatgcagata tatttgtata ctcatcaagt tcagattatg caccaaactt
    14461 agattctata aaatctagtg cacctgtatt ggctgatttg gatgttgtaa aaaatggaaa
    14521 cttatgggtg tttgctccag attattatca atcagtagat aagacggacg aattaatagt
    14581 agatttagtt gagatgtttc acccaggtac tacaggtgaa aaaatcaaac attatataaa
    14641 ttatgataaa tagtacagaa aggacaaaaa aagattggtt ttatagattt tagttaatat
    14701 agctttgcta agaggagtat acaaatggat tttattaata aaatgagaat aaggaatact
    14761 acaatattta tagtgctaat tataagtatt atacttactt ttttagtgtg tgtagcattt
    14821 ggttctgtaa aaattgaatt taaagaagta atagatgttg tattaagggg aatggataat
    14881 acagaacatt ataaaataat atacaatata agaatcccta gagtacttgc aaccatggta
    14941 ggtgggtcat gtttagcagt atcgggtatt ttattacaaa tatttttcaa aaacccaata
    15001 gttgaaccat atatattagg ggtatcttca ggctctactt tatcagtagc actcatgatt
    15061 ttgggaggat acacattggg ctttgagagt gtaaattcaa tgagtatatt tgtagcagca
    15121 tttataggag ctttaattgt aatgtctata gtcattctat ttgcaaataa ggtaagaaat
    15181 ataacaactc ttttaataat aggaattatg actggatatg tgtgtagtgg tataacaaat
    15241 gtgttgcaat catttgcaaa tagtgataaa ttaaaggaat ttactatgtg gtctatggga
    15301 agtttttctg gatttacatg ggaaaaggta gaaatactta taacagttgg tgtgttaggt
    15361 cttttgatga ctgtattcat aataaaacct ttaaatgctt tcttattagg agaagagtat
    15421 gcaaaaagta ttggtataaa tataaaattt tttagagttt taatagtatt tatatctagc
    15481 atattggcag caatagtatc agcatttgca gggcctatag gatttattgg acttgcagtg
    15541 ccacaagttt caaaattgat atttaaaaca tcagataata gaattttgat accagtagta
    15601 atatttttag ggagtatagt tacagctctt tgtgatttaa tatcaagagt agttttatcg
    15661 ccagtagaat taccaataag tacgataacg tctttattag gagctccaat tgtagtgatg
    15721 ctattgatga aaaggaagga tagggcttag acatgttgaa aactaataat ttaagtgtag
    15781 gatacaataa taaggtagta gtaagtgata taaatataga agtaaaaagt ggagaaatac
    15841 tatgtctttt gggaagtaat ggagctggaa aaactactct attgaggtcc ttatctaagc
    15901 ttatatcacc aataaaaggt gagatatatt tgaacggtgt aaacataaat catatatcaa
    15961 gaaaagcatt atcaaaaaaa atggctttag tacttacaaa tagattatta gctgatttaa
    16021 tgactgtaca agatatagtc aatataggaa ggtatccata tacaggattt tttggtaatt
    16081 tatctaagaa agatttaata atggtagatg aagcattgga gtctgtagat gccttacatt
    16141 taaagaaaag atattttgat gaactaagtg atggagaaaa acaaaaggta ttggttgcaa
    16201 gagctctcgt tcaagaacca gaaataatca tattggatga gcctacaact cacttggata
    16261 taaaacatag attagaactc ataaatatac tgaaaaattt aagtaaagaa aagtcaatat
    16321 cagtaatact ttcattgcat gaaatagaca tagcattaaa aagttgtgat aaggttgctc
    16381 ttataaaaaa taataaagtc atagcttatg gtcagcctga agatgtagtt gatgagaata
    16441 ttataaattc actttatgaa ttagatgata aaaattttaa tagtcttttg ggttcagtag
    16501 aaattagtaa taaatctaaa aatgaagttt ttataattgg tggtggaggt aaagcgacac
    16561 caatttatag agcttttact aagaaaggta taggtctata ttctggaata atacatgaaa
    16621 atgatattga ttatgaaatt ggtagaacta tggggataaa aatgtttaca gaaaatccat
    16681 ttgagtcgat aagtgatgag agtttcgatt tggctattag aaatttaaat gcttctaaga
    16741 ttataataga tacaggattt agtgtaggag aaacaaacaa gaggaatata gacattgtaa
    16801 aagaggcttt aaaattggat aaaaaagttt attcttttag aaatagagat gagagtaaga
    16861 agtattatga cagcttggat aacaagatag aacatgtaga taaagtttct caaatcgtag
    16921 atagtattaa tatgaataat ttactataac ctttaaaatc aaatatacca gtaaattaca
    16981 aaatataaaa agatgagtgg ctcaaaatgg actttttagt tcatgaggca ctctttttgt
    17041 atgaaattaa atatattttc attatttcaa caatgaaaaa aggcttatct ctattttgag
    17101 acagaccttt ttttatcatt tatgtatttt atatgtgtcg ttataaaaat aagttacttt
    17161 acagataacc aatagcttcc tctctagtta aaaaaaagtg aatccctgtg gttgattctt
    17221 tccatctatt ttcattaaaa tctttagcta caatcgtttc tcctactcta tatataaaat
    17281 tttcatcagc atatgcacga gcgcttttaa aagattcttt accatctata ctagtaattg
    17341 atagtacttt tgccttatca catctacaag catttgatgt agcagatact ctttttgcgt
    17401 cgctaggtat taataattgt accattctaa aattaaaaca ttttttatag cctataaatg
    17461 ctcctgtttc aggacagtac aatttaaaaa aacgagtact tttatctgat attactccat
    17521 ttaaagtagc atattctaaa ttagaatttt ctaaattagc tcctctaata tctgaattag
    17581 ataagtcaca aaatctaaaa tttgcaccac ttaagtctgc attttttaat atagaatttt
    17641 ttaatgaaca atccgaaaga taagaattat taaaaataga gttttctaaa tctgcttttt
    17701 ctaaatttaa attgataagg tcagaccacg aaaagtcaat attacttaag cagtatcctc
    17761 ttaaatccat gttttccaat cttaattctt ttaaatctgc cttttctcca gtattattgt
    17821 ttttaagcca taaataatgt ttctcaagtg ttttttctaa ttcttgttta gaaatagttt
    17881 tcattaaaat caccttcaca aatttatttt tatatatgta gtagcaaaat agtcatatat
    17941 ttaattatat aacaataagt aaaaaacttc taaataatat ataaaatatc atctttaaaa
    18001 taattttttt caatatagta taatatattt ttaggctatt tagagatgat ttgaaaattt
    18061 aaatatatca taataagctt atattgtttt atatttgagt tgataaaaat ttctttaaac
    18121 aaaaataatg tcaggtatac aataataaaa gtttagatat aaaaaaattt gtgtatatac
    18181 tatatgtagt atataataga taaagcactg actatatgta gtgcttttgt ttttgaaaaa
    18241 tacttattat atcctataat tatagattag ttttgggatt tcaactaata agtacaaaaa
    18301 gaaataataa gcaaattaaa tgaaattata gcacaagatt atgttaaaag gacggtaaat
    18361 aatgaattgg atagagctta acaatcaagt gataattaaa aatgaacaag gtaagtatca
    18421 gttggaaaag gatagggaag ccttaagtag ttacatagaa gaatttatac aaccaaagtt
    18481 aagaaaattt aataacctag aagaaagatt gaagtattta atagatgaag gttattattc
    18541 aaaagaagta ataaatcagt atagcatgga ctttattaaa aatatatatg agattattga
    18601 taaacagaag tttgaatttc aatcttatat gagtgcaaat aagttttatc aaaattatgc
    18661 attaaagagc aatgatggaa agaaaatatt agaaacatat aatgataaag tgttaattgt
    18721 agcattgaca ttgggaaatg gcaataaaga cttagtttta aacttggcag ataaaatagt
    18781 aaaacaagaa tttcaaccag ctacacctac ttttttaaat gctgggagaa aaagagctgg
    18841 agaaatggta tcatgttttt tactatctgt agaagatagt acagaaggta tatcgtatgc
    18901 tatatcttca tcaaatcact tatcaaagat tggtggagga gttgcactga atttatctaa
    18961 acttagagca tctggagaat ctatcaaaga tatagaaggt gctgctggag gtgttgttgg
    19021 agtagctaaa atgttagaac aatcatttag ttatttcaat caaatgggag ctagacaagg
    19081 ttctggtgca gtgtacctta ctgtattcca tcctgatttt gaattattga tggatactaa
    19141 aaagataaat gcagatgaaa aaataaggct tgctacatta tcattaggag ctataatccc
    19201 agataaattt atggagttgg cagaaaaaaa tgaagtagca tatgcatttt atcctcatac
    19261 tgtgtataag aaatatggcg tttctcttga tgagatagaa atgaataagt ggtatgataa
    19321 attggttaat gataatgata taagaaaaaa agaaataaat cctaggcaga tgttgacaaa
    19381 aatagcacag atgcaacaag aaagtggata tccatatgta gtgtacatag atacagctaa
    19441 tagagaacat acattaaaag atattggaat tatcaagatg tctaacttat gttgtgagat
    19501 atttcaatat caaacacatt cagaaataga ggggtatgga ggcaaaaatg aatggggaca
    19561 agatataagt tgtaatctgg gttctttaaa tatagccaat gtgatggata ataaaactat
    19621 agaaagtaca gttgaaacag caataagagc attgtcattt gtagcagata gcacagatat
    19681 aaaaccagtg ccaacagtaa gcaacagtaa cagcaagtct cactccatag gactaggagc
    19741 tatgaattta catggatact tagtaagaga aaatatttta tacacttcag atgatgctat
    19801 agatttttct aatgtatttt ttgcaatggt tagatactat tcaattaaag cttctatgaa
    19861 aatagctata gaaaaaaatc aaacttttga agggtttgat aaatcagaat atgctaaggg
    19921 aagaaatagc aaggttttat caaaatacta tgaacaatct tatctgccta agtcggaaaa
    19981 ggtaaaagcg ttatttgaag ggatttatat accaacaaaa gaagactgga caaaattatt
    20041 agatgaggta aaagaaaaag ggatatataa tgcatattta atggctatag caccaaccca
    20101 aagcattagt tatgttcaaa attctacatc aagtataatg ccaattactg agccagtaga
    20161 agtaaggaca tatggagatt ctactacaat atatccaatg ccatttttaa caaatgataa
    20221 tatattgtat tatcaatcag catataggat ggatatgaga aaggttatag atttagtggc
    20281 aacagttcaa aatcatgttg accaaggtat atcaacaaca ctatttgtta cagatgaaaa
    20341 gacaactaga gatatagcta gacattacat atatgcctat aaaaaaggtt tgaaaagttt
    20401 atattacaca agaacaaaga tgacaagaga cactcatgag tgtctagtgt gttcagtata
    20461 gggagagaaa tatatgacat ttaatttaca taaaatacat aatgcagtta actggaatag
    20521 agaggaagat ggatttacac aggctttttg ggaacaaaat gtaaaacaat tttggcttcc
    20581 tgaagaaata tctgtttcta aagacataaa gatatggaat gaactaagta ataaagaaaa
    20641 ggaattatat aaaaaagtat tgggtggttt aacattatta gatacaaaac aggggaataa
    20701 tggaatacca tctatgatga gtttaacaga aaacttacaa agaaaagctg tcttgtcttt
    20761 tatggggact atggaagaaa tacatgcaaa aagttattct tctatattta tgactctact
    20821 ttctaattcg gaaatagatg aactatttga atggatagaa acagaaccaa cattacaaag
    20881 aaaggcagat ttagttttag ctcaatacga aaatactaca aatcaagagg gattatactt
    20941 atcaatggtt acaagtgtat ttttagagag tttcttgttt tattcaggat tcttttatcc
    21001 attgtatcta tctggtcaag gaaagatggt agctagtgga gaaataatat cgcttattct
    21061 tagagatgag tctttacatg gtaagtacat aggattgctt gcacaagaaa tatacgattc
    21121 atttgataaa atggataagg agatattaga agagaagatg tattctatac tttatagact
    21181 tatggagaat gagatagagt atacaaatat tatatacaga gaaagtggtc ttgaaaaaga
    21241 ggttgtgaat tttttaaaat acaatgcgaa tagagcctta gaaaatctag ggtttgagaa
    21301 gttatatact gtagatgcta taaatccaat tgtattaaat ggtcttagca ctgaaactaa
    21361 aacacatgat ttcttttcga ctaagggtaa tggataccaa aaaggagtgt atgaggaatt
    21421 agaggatgaa gattttataa tataatttat aattatgaca taatgttgtc acttttagca
    21481 tgataatatc aatgtatgaa atatatgtgg aggtattttt tatgaaatat gaatggagaa
    21541 aaagagataa agagctatat ttacctaaaa agaatcctgc aataattgaa gtaccagaac
    21601 agaaatttat catgttaaaa gggaatggag acccaaattc taaagaattt actgaagcaa
    21661 taggagtact ttattctttg gcatatgcaa taaaaaccat gcctaaaaag ggaattgtcc
    21721 cagaagggta ttttgactat actgtttttc ctttagaagg catatgggat aaaggagaaa
    21781 aaagcaaatg tttagatgta cttattaaag aagatttaat ttatactcta atgatacatc
    21841 agccagattt tgttacacaa gacctgttgg ataaagctac tgatatagta aagaagaaga
    21901 aacctcataa tcttcttgaa aaagttagat ttgggtctat taatgaaggt ctatgtgttc
    21961 aaatgcttca tataggttca tatgataatg aaccagaaag ctttgatatt atgaacgaat
    22021 tttgtaaaaa aaataaactt ataagaaaat cttacataca tcatgagatt tatataagtg
    22081 atgctagaaa agtatcgccc gaatcattga agacggtttt acgttttgaa gtagaaaggg
    22141 aagtataaat attttgaata atttataaga gttataaaaa gtgaagtctg ttgagacttc
    22201 attttttgat gcagttttaa aattaaattt gattaaaaaa tagctatgca cacttgtgac
    22261 tttagtcatg agttagtagc taaa
//
LOCUS       DBGJFK010000061        22058 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.061, whole genome shotgun sequence.
ACCESSION   DBGJFK010000061 DBGJFK010000000
VERSION     DBGJFK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22058
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.061"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            184..1455
                     /locus_tag="ACOIAP_002681"
                     /pseudo
     CDS             184..1455
                     /locus_tag="ACOIAP_002681"
                     /inference="COORDINATES: protein motif:HMM:NF012593.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
     gene            complement(1605..2309)
                     /locus_tag="ACOIAP_002682"
     CDS             complement(1605..2309)
                     /locus_tag="ACOIAP_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGZ2639561.1"
                     /translation="MQQGSDYLKKILEKHIDLLKKIPLFEGIKSDELEAMLECLGVVD
                     KIYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEILFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSNKFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFYKNKFEIFCFQK"
     gene            2470..3195
                     /locus_tag="ACOIAP_002683"
     CDS             2470..3195
                     /locus_tag="ACOIAP_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639562.1"
                     /translation="MMRKIIKIDEKKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKTQNKNLACGCPGSQSKSINRE
                     GSNNASISNDVVETKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEIDYTEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3254..4846
                     /gene="hcp"
                     /locus_tag="ACOIAP_002684"
                     /gene_synonym="priS"
     CDS             3254..4846
                     /gene="hcp"
                     /locus_tag="ACOIAP_002684"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016661 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HGZ2639563.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGDTANLQDELTGVLIGL
                     SRATIGNKNRPTSKTDKIMIEGLFTTITNVSFDDEAIKRQIEKTEIEKSKIVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYKEDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGDIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5224..6129
                     /locus_tag="ACOIAP_002685"
     CDS             5224..6129
                     /locus_tag="ACOIAP_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HGZ2639564.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKHIFNKSYTEMLRPKYENKNLKEVLLRIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6253..7206
                     /gene="msrA"
                     /locus_tag="ACOIAP_002686"
     CDS             6253..7206
                     /gene="msrA"
                     /locus_tag="ACOIAP_002686"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGZ2639565.1"
                     /translation="MVKLATFAGGCFWCMVKPFDKYDGVIKVISGYTGGHIENPTYQE
                     VCSGTTGHVEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESKEHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPKEDMETLGYGEYLKLFE"
     gene            7359..8489
                     /locus_tag="ACOIAP_002687"
     CDS             7359..8489
                     /locus_tag="ACOIAP_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGZ2639566.1"
                     /translation="MNLKDFNGKKLKSARTFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINVVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPSRKVMSDININDIESLAYKTREFWDLNSTPIVNMVNLLES
                     KGIIISGMNVDRKWATIFTQKQRISKESKYIISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPNKQFSEDEYACAFLLPKDIFLEDLIHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LGKINYKKYNYLVNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLDEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDSKK"
     gene            complement(8606..9574)
                     /locus_tag="ACOIAP_002688"
     CDS             complement(8606..9574)
                     /locus_tag="ACOIAP_002688"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGZ2639567.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFIVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRLLSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPNTYSNLDLP
                     SIVEKNKKTGINIINGKDCTEFGIGTALVEIVKAILHNEKKILPVSTLLENQYNERNV
                     FASVPCVIGKDGIEEIIEINMTEDEQNEFNKSCSVLREYIALSKTL"
     gene            10148..11347
                     /locus_tag="ACOIAP_002689"
     CDS             10148..11347
                     /locus_tag="ACOIAP_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHHA1 domain-containing protein"
                     /protein_id="HGZ2639568.1"
                     /translation="MEKLYYTDQYIKDFTAEIVEIKEVENKFHVLLDKTAFFPGGGGQ
                     FADLGKIDNYDVISVYEEGKKVYHVLDKKPIKIHRVKCSIDWNRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGSEYSTVDIEGNLDEDKIREIELLSNEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVVKIGDLDTNACCGVHPKATGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDDILKRDIYLTKICRYLSCNEEDAINGIVNLNSKVEEVLIKKRRLE
                     EVVSTYQVKEMIEKANKIGNISVVKKIYEDEDLKYVNKIANKITEHENNIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKILAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            11399..11899
                     /locus_tag="ACOIAP_002690"
     CDS             11399..11899
                     /locus_tag="ACOIAP_002690"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639569.1"
                     /translation="MEQQKDYIELYENEELIEIREACMNDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENMSAKATYESLNMYECDYNMY
                     EYEVMR"
     gene            12001..12318
                     /locus_tag="ACOIAP_002691"
     CDS             12001..12318
                     /locus_tag="ACOIAP_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639570.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASIFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     IIQ"
     gene            12476..13435
                     /locus_tag="ACOIAP_002692"
     CDS             12476..13435
                     /locus_tag="ACOIAP_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGZ2639571.1"
                     /translation="MGESKKSENLLLSIIYIIFFVYILMIIRIILFRDVPIYAISKGT
                     FRTVNLIPFYTIYQFIVDSNIDFMKATINIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     TIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGITIYINMNKLFPNDIKRFKVII
                     ATSLILGVIGLGVISKNYHNLLTFKFRPDKKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            13550..14335
                     /locus_tag="ACOIAP_002693"
     CDS             13550..14335
                     /locus_tag="ACOIAP_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HGZ2639572.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGIMSVLIIRFIHPFIKDFVGIIPYRILISMSIITTLWAILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            14627..15946
                     /locus_tag="ACOIAP_002694"
     CDS             14627..15946
                     /locus_tag="ACOIAP_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGZ2639573.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(16020..16454)
                     /locus_tag="ACOIAP_002695"
     CDS             complement(16020..16454)
                     /locus_tag="ACOIAP_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639574.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RRKDDKKKGNKKRNTNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAIL
                     IITKLTDSTNKGTYSRNTVSNTHKNDIRNVVFNESNNFLICG"
     gene            complement(16545..17921)
                     /gene="hydG"
                     /locus_tag="ACOIAP_002696"
     CDS             complement(16545..17921)
                     /gene="hydG"
                     /locus_tag="ACOIAP_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HGZ2639575.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLISEEIDKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(17922..19007)
                     /gene="hydE"
                     /locus_tag="ACOIAP_002697"
     CDS             complement(17922..19007)
                     /gene="hydE"
                     /locus_tag="ACOIAP_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HGZ2639576.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDTYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(19043..20251)
                     /gene="hydF"
                     /locus_tag="ACOIAP_002698"
     CDS             complement(19043..20251)
                     /gene="hydF"
                     /locus_tag="ACOIAP_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HGZ2639577.1"
                     /translation="MSLNSTPQSIRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGKLGELRISKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLAKNKVKCPVVSVSSTDKIG
                     IENLKNEIIRVLPKDGTEFRLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKENSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALETLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(20266..20517)
                     /locus_tag="ACOIAP_002699"
     CDS             complement(20266..20517)
                     /locus_tag="ACOIAP_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0065007 - biological regulation [Evidence
                     IEA];
                     GO_process: GO:0065009 - regulation of molecular function
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TM1266 family iron-only hydrogenase system
                     putative regulator"
                     /protein_id="HGZ2639578.1"
                     /translation="MKKVAVISAILEEPKECQLKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDIINSLTGKLGNIPHVSVKTSISKKEI"
     gene            complement(20898..21938)
                     /locus_tag="ACOIAP_002700"
     CDS             complement(20898..21938)
                     /locus_tag="ACOIAP_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGZ2639579.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLECKKDFEDLGLDTL
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAMVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVVTRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFETTESGFIKSRYIDNKSAVAMVLEICRYFKENNLAPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VNVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         8272 a         2665 c         3477 g         7644 t
ORIGIN      
        1 tgaactatta aaaaaagatt aaagatacaa aaaaactata gaaattgaca tatattccag
       61 tatttgctaa agtagctgtt ggggaaaatt acaaaaacta ttaatgcgca ttagataatt
      121 tactttaatt tttttagggt ttggggtaat ttataatata aaatattaga aaggaaaata
      181 taaatgaggg actttttaaa aaattataag tcatcaatta tacttttagc atgtactata
      241 ataggggcga tagtaggatt agtacttggt ccaaaagctt caatactaaa accatttgga
      301 gatttattca taaatgctct cttaatgata gtagtaccat tagtttttct tagtgtttct
      361 tcaggtgttg ctagtataaa aaatatggaa cgctttggaa aaataatgaa gagtacagct
      421 atagtattta tgggaacaac acttgtaatt gcatttttag gtattacatc tgcattatta
      481 tttaatccat ctaaaggatt agatgtatca agtgtaaaaa gtttaatggt ggctcaagat
      541 gcagaaactt tagaatcaaa aggaacatta ttagaccaag tagtatcaag tattacagtt
      601 aaaaattttg gagatttatt ttccagtagc aatttactac aattagttat atttgcagtt
      661 ttagttggaa cagcaatagc tatgatggga gataggggaa atacaataag aaagctttta
      721 tcagaaggaa cggaagcaat attaaaagta gtaagtatag tcatgcttta tgctcctata
      781 gggctaggat gttatacagc tacaataatt ggggaacttg gaagcaaaat aattcaagga
      841 tatgtaaggg tgtttgtaat ttattcgcta acagcagtca tgtatttctt attattttac
      901 agtctatatg cttttttatc tgcaggaaaa caagggttta gacaattctg gagaaatgct
      961 ataaaaccaa tagcaacggc actagctact tcttcaagtt cagcatgtat accatcaaat
     1021 ttagaagcta gtaaaaatat aggagttcct gatgatatat cagaaacagt tatacctctt
     1081 ggaataaata tacataaaga tgggtcagtt ttagcagtaa taataaaagt ggcattttta
     1141 tcaggtattt taggtagtgg aatggcaaat ccagcaacga taggtcaatt atttataact
     1201 gtatttgttg ttggagtatt tatggctcct gtagcaggtg gctgacttat tggtgagatg
     1261 ctcgtggtta gcatcttcgg ttttccagtg gaggcaattc cattgttaac agttataact
     1321 actataactg atattcctaa tactatatta aatacaactg gaaatacagt atcatcaatg
     1381 ttagtttcaa gattagtaga aggaaaagat tggcttatag acaaaacagc aattactaca
     1441 aagaaaataa gctaattata tacttaatta ataaagttaa tagatatctt aattttaata
     1501 aattagatat ctattaactt tttaaataaa aatataaatt taagattcaa atatgatatt
     1561 tataatttga attaactaat ataatatatg tttaaatatc tagtttattt ttgaaagcaa
     1621 aagatttcaa acttattttt ataaaaagat aacaagcctt catcccgcat cttaccaagt
     1681 tctcttgaca tagaacttct gtcaacacac aaaaaatcag ccatttcatt tcttgaaaaa
     1741 gggattgtaa acttgttgct acctgtttgt tctatctgct ttgaaaaata cataagcaat
     1801 ttttcacgag ttgttttacg agaaagcaat tctattttat tgtggagtaa aatatttttt
     1861 tcggctatta attgtagcat gttttcaaca agtctattat gaaatacaca tgtagatgaa
     1921 caaataccag ttacactttt aaactttata aataaaattt cacaagaaga tgttgtggtc
     1981 actgtgacat tacttttatg tagtctagta catgcaaaca cctctccaaa taaatctcca
     2041 ggtaagagtt cagctacgat atttctatta ccttcaatat cttcctttat tatatgtgca
     2101 cttcctttaa gcataattcc tattgaagta acctcacttc caacagagaa tattatgcta
     2161 tcttttggat aaatcttgtc tacaacacct aaacattcta acattgcttc aagttcatca
     2221 cttttaattc cttcaaatag aggaattttt tttagtaggt ctatgtgttt ttctaaaatt
     2281 tttttcaaat aatcacttcc ttgttgcata tgcaaccgat aatttgtttt tattgtacta
     2341 tactaagttt ataaaagcaa ggagataaaa atactactat aagaaatttg aaataaaaag
     2401 atgtagtctt aaaaataaat atataagaag taaatattta aaattaaaaa aatttatgag
     2461 gtgatataaa tgatgagaaa aataattaaa attgatgaga aaaaatgtaa tggttgtgga
     2521 ctatgtgttg aagcttgtca tgaagaagct ataggaatgg taaatggaaa agcaaaactt
     2581 ttaagagatg actattgtga tgggctggga gattgcctac caacttgtcc aacgaatgca
     2641 atttcatttg agtatagaga agcagcagaa tatgatgaag cagcagtaaa agcgaatatg
     2701 gaagcaaaaa aaacacaaaa taaaaattta gcatgtggat gtccaggttc tcagtctaag
     2761 tccataaata gagagggttc aaataatgca tctataagca atgacgtagt agagacaaaa
     2821 ggttctcaac ttaaccaatg gccagttcaa ataaaattag taccaactaa tgcatcttat
     2881 ttaaagaatg caagcctttt aatagcagca gattgtacag catatgcata tggaaacttt
     2941 cataataaat ttatgaaaaa taaggttaca ttaatcggat gccctaaact tgatgaaatt
     3001 gactatactg aaaaacttac agagatttta aaagaaaatg atattaaaaa tatagtagta
     3061 acacgtatgg aagttccttg ctgtggtggt atagtaaatg ctgttaagac agctctacaa
     3121 aatagtggaa aaatgatacc atggcaaata gttactatat ctgtagatgg aaaaattgtg
     3181 gatggagaaa tttaattaag tgaattacag aaaaatttaa taaattttaa taaacaaaag
     3241 ggaggaataa aaaatggaaa aaatgttttg ttttcaatgt gaacaaacag caggaggtaa
     3301 aggttgtact ataaatggtg tttgtggtaa aaagggggat acagctaact tacaagacga
     3361 acttacagga gtgttgattg gtctttcaag agcaactatt ggaaataaga atagaccaac
     3421 aagtaaaaca gataaaatta tgatagaggg gttattcact actataacaa atgtaagttt
     3481 tgatgatgag gctataaaaa gacaaattga aaaaacagag atagaaaaaa gtaaaattgt
     3541 acctagatgt tcagattgct caacaacttg taatagaaat gataactatg atatgaaaga
     3601 tttatggaat gataatgaag atatacgttc attaaaatca ttaatattat ttggattaag
     3661 aggtatggct gcctatgcat atcatgccat ggtactaggt tatacggaca aagacgtaaa
     3721 tgagtttttc tatgaaggat taatagcagt tggaggagac ttgtctattg acgaactttt
     3781 aggtttagtt atgaaaactg gagaaataaa cttaaaatgt atggaattgc ttgatagagc
     3841 aaatactgaa acttatggaa cgccagaacc gactcaggta tctatgaaaa tcgagaaagg
     3901 accatttatt gtagttacag gacatgacct ttatgattta cacaaattat tagaacaaac
     3961 aaaagataag ggtataaata tatatactca tggtgagtta ttaccagcac atgcataccc
     4021 aaaattaaaa gaatataaac atctaaaagg taattttggt acagcatggc aaaatcaaca
     4081 aaaagaattt gataatattc ctgctccaat actatttaca acaaattgtt taatgcctgt
     4141 taaagatagt tatagagata gagtatttac tacagaagta gttgcttatc caggtatggt
     4201 tcatattgat gaagacaaag atttttctag tgtaatagaa aaagcccttg aacttggagg
     4261 atataaagaa gatgttcata tgactggtat taatggagga gatacattaa ctactggttt
     4321 tgcaagaggt acagtttcat ctgtacaaga taaagtagta gatgctgtaa agagtggaga
     4381 tataagacac tttttattgg ttggaggttg tgatggtgca aaacctggaa gaaattatta
     4441 cactgaattt gtaaaacaag ctcctaaaga tactgttata ttgacacttg catgtggaaa
     4501 atatagattt aatgatttag accttggaga tataggtggc ttacctcgtt taatggatat
     4561 ggggcaatgt aacgatgctt atagtgcaat taaagtggca gtttcattgg caaatgcttt
     4621 tgaatgtgga gtaaatgatt tacctcttag tatggtacta tcatggtatg aacagaaagc
     4681 tgtttgtata cttcttacat tacttcactt aggtatcaaa aatatctata taggaccttc
     4741 tttaccagca ttcttatcta agaatgtatt agatatattg gttgataaat ttgcattgac
     4801 gcctatatct actcctgaag aagatatgaa gaagatttta ggataaaaaa ataaatatat
     4861 ctatacttaa atctatttat agttaaaata tttttaagta tagatgcaat taagataagg
     4921 ggttaaactt aaaatttgat taaaaaaatc aattttgaga caacccttta tttatttttt
     4981 gtaataattg aaaattaaac ctgcttttag tatattcttt ttaggaatcc ttgtattaaa
     5041 cttataatgc ttagatatat aatatcttat agattttatt ttaagtagta aaatttttaa
     5101 tggaatttaa atattaaaaa aggaacattg taatatgtaa cttgcataaa atatatatac
     5161 tatagtgaaa ttattttaat taaaatttaa aatagaaagt gttttatgtg ggggtatatg
     5221 tatatgaaaa attctaattt caatatattg gcatttgatg gtggtggatt aaaaggagca
     5281 ttgagtatat ccatacttga gaggatagta aaagagtatc caaatctatt aaataatata
     5341 aatatgtttg gaggaacatc tacaggaagt ctaattgcat taggacttgc atatggtgta
     5401 agcccgaaag agataaaaga gctttactca atcgaaaatt caaaacatat ttttaataaa
     5461 agttatacag aaatgctcag accaaagtat gaaaataaaa atttaaaaga agttttatta
     5521 aggatatttc cagaggaact agaattaaaa gatttaaata aattagtaat gataccaagt
     5581 ttttatatag gaaatgaaga aaatgcatgg aaaccagtgt tttataacaa tatgccaaat
     5641 tcttttacaa agactagtaa agtagtagat gtagcaatgg caagcagtgc tgcaccagtg
     5701 ttttttccaa catataatcg ccatgttgat ggaggaataa tagcaactga cccaagtcta
     5761 gcgtgtataa ttcatgccat tgacagtgga tttaagctta aaaatacaag acttttttcg
     5821 ataggaactg gatatgtata taatagtata aaggcagaca ctactgaatg gggagctatt
     5881 gactggataa ttaataaaga acctgattta ccaattatat ctattacatt agaaggaaat
     5941 tctcaaatga gtcagttatt ttctcaaaaa cttcttggag ataattacta tagattaaat
     6001 cctaagatgg aaaaagatgt agctatggat gattgtgatg cgttagaata tttaatgtct
     6061 ttaggagaaa attgtgatat aaaagatgct tttgggtgga taaagaaaaa gagcttttat
     6121 agaaattaga ttcaatttaa aattgtattt ttacacatga tttcattgaa tatgtaaaaa
     6181 taataaaatg cagattatta agttacttct tagggaataa ataaaatata atttatttaa
     6241 ggagtgatga aaatggtaaa acttgctact tttgcaggtg gatgtttttg gtgtatggta
     6301 aaaccttttg ataagtatga tggagttatt aaagtaattt ctggatatac aggtggtcat
     6361 attgaaaatc ctacatatca agaggtgtgt tcgggaacaa ctggtcatgt tgaagctatt
     6421 caaataactt atgatgatga tataataagt tatgatgagc tactgaatat attttggaaa
     6481 cagattaatc ctactgatga tggtggacaa tttggtgata ggggaactca atataagact
     6541 gctatatttt atcatgatga agagcaaaaa aatatagctt tagagtcaaa agaacatcta
     6601 gaaaatagta aaatattcga tagtaaaata gtaactgata taattccagc aactaagttc
     6661 tatgaagcag aagaaaatca tcaggattat tataagaaaa gaccattaaa ctacaatatg
     6721 tattataaag ggtctggtag atataatttt gtaaaaagtc attgggatgg aaacaatata
     6781 aatagagaag agttaaaaaa gactttaact cctatacaat ttgaagtcac tcaaaatgat
     6841 atgacagagg taccttttga aaatgagtat tatgataata acaaagaagg aatttatgtt
     6901 gatattgtaa gtggagaagt gctattttct tcaaaagata aatttgattc tggatgtggg
     6961 tggccaagtt tttcaaagcc agttatagat aaatctatta ttgagagaag tgatttttct
     7021 caaggtatgt acagagttga ggtaagaagt gctaaaggaa attctcattt aggtcatgta
     7081 tttgatgatg gtccaaaaga gcttggaggt ttaagatatt gtataaattc tgcttctctt
     7141 aaatttatac ctaaagaaga tatggaaact ttggggtatg gagaatattt aaaacttttt
     7201 gagtaattgg aactatttat tataaactta gctaaaaggt gaaaatataa gaaaatattt
     7261 tcaccttttg tttttttgtc aataatatga taaattatta attgtaatct tatttatacc
     7321 agtagattaa gaatttaatt ttgaaagaga gaaaacaaat gaatttaaaa gactttaatg
     7381 gaaagaaatt gaaatcagct agaactttta gagcaaagac gatagaacag ttgtctaaag
     7441 aaactaaaat aaacaaaaaa gatttaaaag cttttgagga aaataagtat gtcccaaata
     7501 tagaaaatac attaaaatta tctaatatat taaattttcc aaaagagtat ttttataaaa
     7561 atgaaaatat aaatgtagtt gtagaggata gccactttaa tcctcaatct aaactaccta
     7621 gagtagaaga aatttcttat agagaaaaaa taattataat acataaaata tattctttta
     7681 tggagaatta tattaagttt ccaaaagaaa acttaccaag tagaaaagta atgtcagata
     7741 ttaatataaa tgatatagaa tctcttgcat ataagactag agagttttgg gatttaaata
     7801 gtactccaat agtaaatatg gtaaatttgt tagagtctaa agggattata atatcaggta
     7861 tgaatgtaga tagaaaatgg gcaactattt ttactcaaaa acagagaatt agtaaggaat
     7921 ctaaatatat aatatctctc ggtaatgata aaaagtcagc atcaattaga aattatactt
     7981 tggcatgtga gcttgggtat ataatatcaa gtgaattaag aataccaaat aagcaatttt
     8041 cagaagatga gtatgcatgt gcatttttat tgccaaaaga tattttttta gaagatttga
     8101 ttcatccaga agatttggat tattatgtag aactaaagaa aaaatggatt gtacctatat
     8161 ctgctatgat ttttagagcg tataatctag gaaaaataaa ttacaaaaaa tataattatc
     8221 ttgtgaatga aatggataaa aaaggctggt taatagaaga accactagac aaaatgaaag
     8281 gttcaagccc aacgtattta aaaagagcag ttgaattatt gatagaaaat aaaataatga
     8341 gcgtaaatag tatagtatca agtttagatg aatttggaat aaatctttat ccagaagact
     8401 tagaattatt gatgggatta aaaaaaggac tgttatcgca agaggtaaat aaaaaaagta
     8461 aagttataaa atttgatagt aaaaaatagg ttgatatttt agcattaaaa ttaaaagcag
     8521 gtataaatga tttaaacatt aatttaatta aaagtctttt caatgagtca tttacctgct
     8581 tttagtgtaa aaaagaatct tgaatctaaa gtgtttttga aagtgcaata tattctctta
     8641 aaacagagca agatttatta aattcgtttt gctcatcttc agtcatattg atttcaataa
     8701 tttcttcaat accatctttt cctataacac atggaacact tgcaaataca tttctttcat
     8761 tatattgatt ttctagtaat gtagaaactg gaagaatttt tttctcatta tgtagtatag
     8821 cttttacaat ttctactaaa gcagtaccta taccaaattc tgtacaatct ttaccattta
     8881 ttatatttat ccctgttttt ttattttttt caactattga tggtaggtct aaattgctat
     8941 aagtatttgg gttatccttt atcatgtcca agattggttt accaccaatt gaaacatgag
     9001 accaaggaac catttgagaa tctccatgtt cacccataga ataagcttga attgattgtt
     9061 gagcgattcc agtttcttca gataaaagcc ttctaagtct tgttgaatct aaagctgtgc
     9121 cagttccaat gactttgttt ttaggaaagc cagatttttc ccaaatataa tttgtaacta
     9181 catcaacagg attagatatg actataaata taccatcaaa gccagaatca actatgggtt
     9241 ttactataga ttttatcatt ccaatagttg gtcttagtaa atctaatcta gttgtatttt
     9301 gtctacgtaa aggaccttct gaagagtctg caacacttat cactactata tcagaatctt
     9361 tacagtcaga aaaagttcct ttttctatat gtactttgtg tggcagatat gaaactgcat
     9421 cagctaaatc taaagcttga gcttttgatt tagattcatc tatatcaatc ataaagagtt
     9481 catcacaaac tccttgagtt attaaactga atccacaatg agagccaaca tgccctgaac
     9541 ctacaataga tatttttctt ggctttattg ccattttaaa tcactccccc taaaataacg
     9601 atacatttat aagaatatta tatattataa agagataatg tataagctct ataaatttat
     9661 ataaatgttt tatattttta tgattttctt ataaagtttt ataaaatatt agttactgtt
     9721 ttttatgtat tttaatattc tatcatttca gaaaatttat ttaatatgat tttatactaa
     9781 aatttttgaa aaatcaatgt taatatactt tacactaatg aatattaatg tgataaacat
     9841 atattgaaaa ttattaataa tagatgagat tagtaaaagt gattaaattt aatttgtagg
     9901 tttaatatat ttcggtaaat tttttatatt gtaagaagac atggaagcat atacatttgt
     9961 aaaatatcga aataatatac ttataaattt gttaacacta atatctatgt gttaaaatat
    10021 agtataagat tgttagcaaa gaatgggatt agttctatcc tagtacaatt aaattaaagt
    10081 tatactaaga tttgtatatt taaaaactaa agtagtttag aactaaggaa atggagatag
    10141 aattataatg gaaaaattat actatacaga ccagtatata aaagatttta cagcagaaat
    10201 agttgaaata aaagaagtag aaaataagtt tcatgttttg ttggataaga cagcgttttt
    10261 ccctggtggt ggaggtcagt ttgcagactt aggaaaaata gataactatg atgtaataag
    10321 tgtatatgaa gaggggaaaa aagtatatca tgtattagat aaaaaaccaa taaagataca
    10381 tagagtaaaa tgcagtattg attggaatag aagagaagat ggtatgcatc aacactttgg
    10441 gcaacatgta ctgtcaggtt gtttttttaa gactttcaat gcaaatacaa caggttttca
    10501 tctaggaagt gagtatagta cagtagatat agaagggaat ttagatgagg ataaaattag
    10561 agagatagag ttgctttcta atgaaattat tcgtcaaaat atacaagtag agacgctact
    10621 tccaacaaaa aaagaattga aaaagatttg gttaagacgt gatttgccaa atactgatga
    10681 agaaataaga gtagtaaaaa taggagattt agatacgaat gcatgttgtg gagtacatcc
    10741 aaaagcgact ggtgaattga gaatgataaa aataaagaaa tgggaaaaac ataaatctag
    10801 tacaagaata gagtttttgg caggtaaaag ggcagtagat gatatattaa aaagagatat
    10861 atatttaact aaaatatgca gatacttaag ttgtaatgaa gaagatgcta taaatggtat
    10921 tgtaaatcta aatagtaaag tggaagaggt tctaattaaa aaaagaagac ttgaagaagt
    10981 agtgtctaca tatcaagtca aagaaatgat tgaaaaagca aataagattg gcaatatttc
    11041 agtcgttaaa aaaatttatg aggatgaaga tttgaaatat gtaaataaga tagcaaataa
    11101 aattacagaa catgaaaata atattgcatt attagctgtt aaatttaatg ataaaataaa
    11161 tttagttttt gcatgttcta aaaatttaaa agatattaat atgggagttt tattaaagga
    11221 tgcaataagc cttatagatg gtaaaggtgg tggaagtaaa atattagctc aaggaggagg
    11281 taagaataat ggaaatttag aagctacact tgactatgca tttatgaaga tagaaaaaac
    11341 tctataaata tattatataa aaaatcttaa tagataaaat agatatggag gaataagtat
    11401 ggagcagcaa aaagattaca tagagttata tgaaaatgaa gaattaatag agataagaga
    11461 agcctgtatg aatgatttgg atacaatagc aaaatttaat tataatttgg ccaaagaaac
    11521 agaaggaaaa gaacttgaca tggatgtttt aactaaaggt gtaaaagcat tgttattaga
    11581 tgagagaaaa ggaaaatatc atgtatatac agtatttgat aaggttgttg cacagattat
    11641 gtatacatat gagtggagtg attggagaaa tggaaatttc ctttggattc aaagtgtata
    11701 tgtagataag gaatatagaa gaaaaggtat ctttaattat ttatttaatt atataaaaaa
    11761 tatatgtgat aaagatgaaa atattgttgg aatgagatta tatgtagaaa aagaaaacat
    11821 gagtgcaaaa gcaacatatg agtctttaaa catgtacgag tgtgattata atatgtatga
    11881 atacgaggta atgcgttagt aatataaatt tataatatta atattataaa gtattgatta
    11941 tattgacaat tatgtggaat aaattggata ttataattag gaattttagg gggtaaaaaa
    12001 atgggcgttt taaaaggaat gttttatgta tttttatttt tagacttagt atcaatattt
    12061 tgtttctttt ttaataaagg aaaaatagca tctaataaaa ttgtgtttaa tgcaatagga
    12121 gtacttacat ttgtactttg ttttatgctt tttagttatt atcctaataa taatcttatt
    12181 ggaaaattta ttgcatctat attttttata tttggagttg caggagttat gttgaaagaa
    12241 aaaaattttt tatatgctag actcctttta actgtagtta ttgttttttc tacactaaga
    12301 ttgttcatta ttcaataaaa tacatttgta tgaagttttg ttaaagtctg cacatttaag
    12361 tgtaggcttt tttgtatttt tatttagaag ttaagggaat tttaagaaaa ttttaaaatc
    12421 gtcttaaata tttattggta cacttgaaat attaatagat agaggaggct tatcagtggg
    12481 agaaagtaaa aagtcagaga atttgttact gtcaattata tacataatat tttttgtata
    12541 tattttaatg attataagga taattttatt tagagatgta ccaatttatg ctatttccaa
    12601 gggaacattt aggactgtaa atttaattcc attttataca atatatcaat ttatagtaga
    12661 tagtaatatt gactttatga aagctactat aaatattata gaaaatatag gtatatttat
    12721 tcctatggga atttttttac ctatagtatg taaaaatcta aataaaaaaa ctataattat
    12781 aacaattata cttgttagct tagcatttga attaacacaa tatatttttg ctcttggaag
    12841 tagtgatata gatgatgtta ttttaaattc attaggtggc ataattggaa ttactattta
    12901 cataaacatg aataaattat ttcctaatga tattaaaaga tttaaggtta taatagctac
    12961 tagtttaatt ttaggagtta taggattagg agttatttct aaaaattatc ataacttact
    13021 aacttttaaa tttagacctg ataaaaaaat atcaaaaata ttaattgaag aaaataggga
    13081 aataattaag gatataaata aagatacagt agacatagtt gggacatttg agagctttaa
    13141 aaaaggaata ataactatta aagcaggctc taataacaaa gtaaagagac cagagaattt
    13201 aattgattct gatggaaata taagaattta tttaaatgaa aatacaaaat tagtatctta
    13261 tataattacc aaagaatcaa aaatggatat agttaaatat gaagaatttg atgtgaagaa
    13321 tttagattta ttaaggagat atgatactat taatgtttgg attgataaag aaaatcagcc
    13381 aaaggataaa catggtatta tggctagtaa attattaatt ggattgtatg aataaaatat
    13441 taaacaagaa taaaagaata acaaatataa aaaacgaaaa aactatttct ataattattt
    13501 ttacgttgtg cataaaataa gaacactggt gaaggagtag agataaatta tggagataat
    13561 aaaatatatc ttgtactttt ttatatattc atttttagga tggacagtag aaagtatagg
    13621 atgttctata gcaagcaaaa gaataatcaa cagaggtttt ttaaatggtc caatatgccc
    13681 tgtttatggt tttggagcgg taattgtgat atcactattg ggaagattta ataatgtagt
    13741 aatagtattt ctattaggaa tgattttaac tacaatacta gaatatttta caggatttat
    13801 tttagaaacc ttatttcatg ctaaatggtg ggattattct gacagaaaat tcaatataaa
    13861 gggtagagta tgtttaaaaa atgcaatata ctttggtata atgtctgttt taataataag
    13921 atttatacat ccatttataa aggattttgt aggtataatt ccatatagaa tattaatttc
    13981 aatgtctata attacaacac tttgggctat acttgatttg attgttacta ttataacact
    14041 taaaaaatta gatataaaat taaacttact agacgatata attacagacc ttaatgatat
    14101 aaatgtgaaa ttggataagt ttgatagagg agaaatacaa gctttattta aaacaataaa
    14161 taacgacgaa ttagaagtta gagaaaaaat aaacaaaata aatagtaagc tggaccgtat
    14221 agagtctaat attattttac aaaaaagagt tataaaagct tttccacata taaaacataa
    14281 aaaacaacaa gaacaactag aacattttaa aaaaattatt aatgagaaaa ggtaattata
    14341 caatttaatg aaaaagaata gaataatggt atttataaga tgattttcag agggctctat
    14401 aaaaatagaa tagagtcctt tattttttga aaaataatgt ttatttgata aaaataaaat
    14461 atattgtttc tgaataacaa atattttgaa aattataaaa acatatattg acaatttgtg
    14521 tcaaaaatac taacattaag tatataaaga attttatatg agaatatctt tataaatcgc
    14581 aataatttta aaacataaat ttatttaaag aggggatgat ttgccaatga gcgagataac
    14641 tagtcaaatg ataagtacag aagaaaaaaa atatgttgct aaaactcaaa agatacctta
    14701 ttatccagta gcatttaaat caggtgatgg tgcaatgcta tatgattatg aaggtaatga
    14761 atatgtagat tttttagcaa gtgcaggctc tgcaaatgta ggtcatggta ataaggaaat
    14821 ctcacaagca gttaaagaac aaatggatga tataacacaa tatacacttg catatttcca
    14881 tagtgatcct cctgtaaaat tagctgagaa gcttgtggaa atagcccctg gagataatga
    14941 taaaaaagta ctatacagtg caactggttc tgcttgtata gatgctgcta taaaattagc
    15001 aagagggtat actggaagaa caaagataat atctatgtgt gaatcttatc atggaagcac
    15061 ttatggagcc atatctatat ctgctttaag tacaaatatg agaagaaaaa tgggtccatt
    15121 gttaccagaa gtttatcact tccattatcc tgataaaaat agaacagcta aagaatgttt
    15181 agatgagata gaatatgctt ttgcacacta tttaccagca gaagaagtag ctgcaatatt
    15241 tatagaacca attgctggag atgcaggaat aatagtgcct ccagtagagt gggtacaagg
    15301 tttaagtaaa atatgtaaag aaaatgggat attacttgta agtgatgaaa tacaacaagg
    15361 tatgggaaga acaggtaagt ggtttggtat agaaaatttt ggtgttgaag cagaccttat
    15421 agttcttgga aaatctgttg gaggtggatt acctctagga gcagttgttg gaagaacaga
    15481 aataatgcaa agtcttgatg caccagcaca tttatttact ttagctggaa atacaacagt
    15541 atgtgtggct gctttaaaat ctatagagat aattgaaaaa gaaaacttac ttcaaaagag
    15601 tatagaaatg ggagattata ttaaagcagg atttgaaaaa ctaaaagaaa aatatgatat
    15661 aattggagaa ataagaggta taggattatc tataggagtt gatatagtta aaggaaaagg
    15721 ttctaatgaa aaacatccag atgctacagc taagatatgt tatagatgta tacaaactgg
    15781 attaataatg atattcttag gacaatctac tttaagagtg caacctcctc tagtaataac
    15841 taaggagcaa gtagataaag caatgaacat catagattct gcaatagatg attatttaaa
    15901 tggtagaatt ggtgatgaag tatatgaagt aactcaaggt tggtaaaata aatattaaat
    15961 aaaataagag ttatctcaat tttagaaagt aatttctgaa atgagataac tcttttaagt
    16021 tacccacaaa taagaaaatt gtttgattca ttaaagacta catttcggat atcgtttttg
    16081 tgagtattag agacagtatt gcgagaataa gtacctttat tcgtactatc tgttaattta
    16141 gttataatta agatagctaa aagaataaga attactgtgt ataaagcaat aacgtatggt
    16201 tttcttttat atttgtattt attattaaaa aaagaatgac cataattatt tttatttact
    16261 ttagatgtat ttgtatttgt attccttttc ttgttacctt tctttttatc atcctttctt
    16321 ctatttttag ggtaaggaat gactttgtgt gtattatcaa gtttgatatt tttatttttt
    16381 tgaatattgt tttccaggct agcctttttt tctccaaatt gaatagtttt attggtattg
    16441 ttgttatctt tcaatgttaa tctccctccc ttaaactttc cctttagata atattactac
    16501 taacctatgg aatatacaat aaataatata taagtaataa aattttatag gtataaatct
    16561 ctttctccac gctctaatgc agtcatattg ttagatacta tgtttcttat atcttctctt
    16621 tctatcttat ctatttcttc tgagataagt tttttaccca taattttaag ttcttcatct
    16681 ccataatcga ttagaaattc atttaatgta gtaagagcat ttggtgtaca tacattatga
    16741 atttgtcgac ttttagctaa gctcataaat ctatcgccag ttctaccctt gcgataacaa
    16801 gctgtacaat agctaggtat atatccatca gtaattagtt ctttaagaac ctctacaggg
    16861 cttctatggt ctccaacttc gaattgttct gtattgtcac catcttcata tgctttatat
    16921 cccccaactc ctgttagaga acctgcacta atttgtgata caccatattt tagtaactca
    16981 tttctcattt cagcagtttc tctagtggac attatgattc cagtaaaagg aacagctaat
    17041 ctagttatag ctactatttt tttgaacata tcatcagaaa ctaagtgagg aaaatcttct
    17101 aagctcatac cttcagcttt tttcaatcta ggaaaagata tagtatggaa acctacacca
    17161 aatttttcct ctaagtgttc gttatgcatc ataagcccta gaacttcaaa tttagggtca
    17221 gataaaccaa ataaaactcc tgcaccaaca tcatcaacgc cagcttccat agctctatca
    17281 aaagctgtta aatggtaata atagtcattt tttatagatt gaccatgcat ttttataaat
    17341 gttggtttgt gataagtttc ttggaataat atataagttc ctattccttt ttcttttagt
    17401 aatttatact catctacact tgtagctgct atgttaacgt ttacccttct tatatttcca
    17461 ttttcgttat atgttgaata aattgcatct aaacaatcta agatataatt tatatcacaa
    17521 tttttagggt cttcaccagc ttctagagca agtcttttat gacccatttt ttctaatatt
    17581 ttaacctctt cctttatctc ttccatggta agtttttttc ttttaaattt gttgcatttg
    17641 ctaaaaccgc aataaacaca ttcatttaca cagtagtttg atacataaag aggggcaaat
    17701 aaaaccactc tattaccata tatttcattt tttatttgcc cagctatact aaataatcta
    17761 tctagttgtt ttttatcttc tacttcaaga agtgtagcta tatctttata actaagtttt
    17821 tcccttctat cagccttatc aagtaccttt tcaatatcat cagaagttga attttttgca
    17881 tcttctaata aagaattaat aagttcatgg tttatgaaca tttacaaacg cctccattca
    17941 atattatcac cacgagaata gtcgacttca agtcctaatg acttgatgtt ttcttctaag
    18001 ctttggtgat attcacaagc ttcttgacca gtaaaggctt tgttatcgta aagagaatat
    18061 tgttttctaa attcttgagg agaaaggttt ggcataatta cattgcaacc agctaaaaga
    18121 cctgcatttc taccactagg gtttatagat gccaaggctg ttgtagcagg taataaaact
    18181 tttggaagta gaagtcttgt aattgaaagc ataagtaatg tcttttctaa atctccatgt
    18241 ttataatcct taaatattgt atcatggtgt ggaataaaag gtcctattcc aaccatatga
    18301 ggatttaact cttttaggta taataaatca cgcacaaggt cctcattgtt ctgaaatggt
    18361 gactcaacca taaatccagc acctacttga taaccaattt ccttaaggtt ttttaggcat
    18421 tcttttctag ttctaagctc aatgtttggt ggatgtaatt ttttataatg actgtctgta
    18481 gcagtttcat gtcttaaaag atatctatct gcaccacata aaaagtattt tttatacgaa
    18541 tcataactct tttctcctag tgatagagtt atggcacaat cctcatattt attttttata
    18601 cttgaaacaa tttcacatat tttatcatca gtaaaatatg tatcctcacc accttgcaaa
    18661 acaaatgttc tatatcctat tttataacct atatcacaac attcaagtat ttcatcaagt
    18721 gaaagtctgt atcttatgat atttttatta gaagattgta ttccacaata gtagcaatta
    18781 tttttacaat agtttgtaag ctctataagt cctctcaagt agactctatt tccgtaatgt
    18841 ttatttctca tgtcgctagc ttgtttataa agatagtttc ttaaattttg ttcgaagtta
    18901 tattcttcat tatcgatatt ttctattaaa tatagtagtt catcaaaact taatgaatta
    18961 atgctgtaaa gtttatctat aaagtattta atcttatttt tagtcatatt caaatatgta
    19021 attattaaat atagttaaat ttttaataat tgaaaagttc aagtgatctt tctaaaatac
    19081 cttttacata tgctattaaa ataccatagt ttacaatcgg tacattgaaa gattttgcct
    19141 tttctattct agataacatt ccagctctat tcatcataca agctccacag tggactacaa
    19201 gggcatattt atttatatct tcagtgaagg atactccaga actaaattca aaagtaatat
    19261 ttttgccagt tttctttcta atcatattag gaatttttac cgttccaata tcatcagttt
    19321 gtctatgatg ggtacatcct tcggccatca agattttatc accatctttt aaagtttcta
    19381 aagcataagc tccattaatc aactctttaa ggtctccttt ttgtctagca aataatatag
    19441 aaaaagatgt aagaggaata tcttttggtg tatctttatc tacttgtgga aatacttgag
    19501 agtcagtaat aacaagtttc ggttttttgc ctaaattaga tagagtttct tttaaactat
    19561 tttcttttgt aactatagaa attgcaccat tatccaaaat atctcttata acttgttgtt
    19621 gaggaagtat aagtctacct tttggagctg ctttatctat tggaacaact aaaacaacta
    19681 aatcatttgg ttcaattaaa tccgatacca atctgaactc agtgccatct ttaggcaaaa
    19741 cccttattat ttcatttttt aaattttcaa tcccaatttt atctgttgat gagacagaaa
    19801 caactggaca tttaacctta tttttagcta agtttaaaat ttctgattga ttcttaatag
    19861 tatcaatttt gttaagaatt aaaatatgag gtatattctt atcattaaac ttttcaatta
    19921 gtgataaatc ttcttgtgat ataccaattt ggcaatccac tactagtaaa gctatatctg
    19981 tcttttctaa aacatctagt gatttactta ttctaagttc accaagttta ccaacatcat
    20041 caagaccagc agtatctata agaacacaag gtcctatagg aaggatttcc attggtctaa
    20101 atactgggtc tgtagtagtt ccagcaatat ctgatactat tgcagcgctt tgatttgtta
    20161 tagcatttat tatgctagat ttacctgcat ttcttttacc aaagagacct atatgcactc
    20221 ttattgattg tggagtagaa tttagactca tttgtactca ccaccttaaa tttctttttt
    20281 tgatatacta gtttttacag atacatgagg tatgttgccc aatttaccag tcaaactatt
    20341 aataatatcc atttcgccaa caactgctat acatacgatt gatacacctt cttcttcgca
    20401 aggaatgccc attcttccct taataatacc tttaaaacct gatacaacct cattgaattt
    20461 aagctgacat tcttttggct cttccaaaat agcacttata actgcaacct ttttcataaa
    20521 tatcctccta actcagaaaa tatgtcttaa acaaatccaa aatcaaaaaa cttttctttg
    20581 taaagaaaag tttctacaaa agaaaagtta ttaattacac aagtataatg tgctatatta
    20641 aactatttcc ttacagatta gataactctt ttctggtagg gttagcttgt aaaaatttaa
    20701 tttaacaaca attaactgaa gaatattttt atacaattta tataaattat aataaaaatt
    20761 aactaaagaa aattgaagtt acttatataa tagtagtaaa ttgaaattaa gtctatagaa
    20821 aaaccaattt ttgtataaaa ataaaaatta aagctagtta tttgttaaga attgactttg
    20881 gtaaaatata tatttaatta ttctttaagc atataattta taagtaattt tagtgtattt
    20941 tcaatagctt ctatatgtgt tctttcataa tggtgactat tgtttgttcc aggaccaaca
    21001 catgctattt gaacatcttc tccccaacga atagcttctg aagcatctga accatagaaa
    21061 gtaaatacat cgacagcgta gtctaaatta ttgtcctctg caacattcac aagcttgttt
    21121 cttaagttaa aatcatataa tgataaatta tcctttgcaa ctatagttac accatgttca
    21181 ctagatgtct gacttggtcc agtaggtgct atatctattg ctacaaattc ttttgttttt
    21241 tcaggtaaac atttagaaac accatgtcca atttcttcat aattgcttat ataaaagtta
    21301 gtagtatgct taggtgctaa attattttct ttaaaatatc tacatatttc aagaaccatt
    21361 gctacagctg atttattatc tatatatcta gattttataa aaccagattc tgtagtctca
    21421 aatcgatggt ctagacatac aaaatcccca acacttattc ctaagtctaa tacatcttgc
    21481 tttgtaaata ctttttcatc aagtctaata atcattgttt cttcatttct ttcagtagcg
    21541 gctttggttt gaccatatat atgagtagaa gcatacttaa atacaacact tcctctgatt
    21601 tttttacctt ttctagttac aaccgtacag ttttctcctt ctatagcagc ccaacatcca
    21661 ccaccaactt tatggtattt aagagtacca tcagaggata tttcttttac catagctcca
    21721 agtgtatcca tatgtgcaga tattgttatt tgatttgaat catcttcacc aggaagagtg
    21781 gctataagtg cacctttttt tgtaagaaga gtgtcaagac ctaaatcttc aaaatctttt
    21841 ttgcattcta aaactgcatt ttcagtatat ccagctgggc ttggaatgtc caaatatttt
    21901 ttcattaaat ttatagtatt agttaaattt aaattcatat tgtttcctcc taaataaata
    21961 tatttataca aattataaca taaatacaaa tgttctgaaa actaaaatta aaagaataaa
    22021 atctaaacat atttaaaaaa aagtatataa aataaatt
//
LOCUS       DBGJFK010000062        22038 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.062, whole genome shotgun sequence.
ACCESSION   DBGJFK010000062 DBGJFK010000000
VERSION     DBGJFK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22038
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.062"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            140..787
                     /locus_tag="ACOIAP_002701"
     CDS             140..787
                     /locus_tag="ACOIAP_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HGZ2639580.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEIGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESVCAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(929..1498)
                     /locus_tag="ACOIAP_002702"
     CDS             complement(929..1498)
                     /locus_tag="ACOIAP_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639581.1"
                     /translation="MKKFTICIIMFAISALVLAGCTNDNKIKNEVDNMFNAIKTQDSD
                     AVDKYFPKLGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKVNNTDMVSIL
                     KKNPPKLGAMMPNPTMKDIDSANKKEFNLTLELVKSGDNYVCEVNQESAMKLLNVITG
                     GGTDYLADYNKDYYKQLDEEQKNYENQNN"
     gene            complement(1503..2402)
                     /locus_tag="ACOIAP_002703"
     CDS             complement(1503..2402)
                     /locus_tag="ACOIAP_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2639582.1"
                     /translation="MKLLSNINNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKRLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLYKIPFPVKIKKVYGDKYLKYLKYLVLIIFVIILPVAIVNVAGGGDPWFCKW
                     ICPSGTFLGGIPLILGNENLRESIGFLFSWKLSILLLILLISIMIYRPFCRYICPLGA
                     IYSFFNPISIYRFKIDKDKCTNCTACQAKCKLDIPVYKDVNSLDCIRCGECIKACPHN
                     AITTTFSKDKKENKFCKKKYRGM"
     gene            complement(2413..2562)
                     /locus_tag="ACOIAP_002704"
     CDS             complement(2413..2562)
                     /locus_tag="ACOIAP_002704"
                     /inference="COORDINATES: protein motif:HMM:NF040920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1871A family CXXC motif-containing protein"
                     /protein_id="HGZ2639583.1"
                     /translation="MSNFIKDNKTGISIIVISFIFIVLGTYRGESNTVLTKAIMICLE
                     CIGIG"
     gene            complement(2555..3142)
                     /locus_tag="ACOIAP_002705"
     CDS             complement(2555..3142)
                     /locus_tag="ACOIAP_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HGZ2639584.1"
                     /translation="MKRFFTLVLGCIFVLGVVSGCNKKTETNLVETNKNNSEWFNNLV
                     TEDVDGNKVTKDVFSSKELTLINTWTTWCGPCIGEMPELEALSKEYENNNSNVAIKGL
                     IVEVDGTDMKTGLSDKEKELVKDIMKKSGATYQQLTVSEGLKKTDFKRTIEFPTTYFV
                     DKKGNFVGEKVTGANSKEEWKKIIDERLKMVKDSE"
     gene            3565..4890
                     /gene="cdeA"
                     /locus_tag="ACOIAP_002706"
     CDS             3565..4890
                     /gene="cdeA"
                     /locus_tag="ACOIAP_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HGZ2639585.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQNEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATNKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGILYFLSSKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGVTTFLFNIVALKLAGESGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIVALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNLTGLWLTVPFAEVLTIFISILFIKKYKGRYKY"
     gene            complement(4985..5779)
                     /locus_tag="ACOIAP_002707"
     CDS             complement(4985..5779)
                     /locus_tag="ACOIAP_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639586.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIMGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYNIELSVLLKRDMIWTSISALIEPSTSSISLTYLNYF
                     VQICLNEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(5780..6655)
                     /locus_tag="ACOIAP_002708"
     CDS             complement(5780..6655)
                     /locus_tag="ACOIAP_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2639587.1"
                     /translation="MSSSIKIENLYHSFKKQNVFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQVFEFSSS
                     FYKNYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKSIKPKKAFGNTVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(6659..7027)
                     /locus_tag="ACOIAP_002709"
     CDS             complement(6659..7027)
                     /locus_tag="ACOIAP_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2639588.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFIKNLLQEA
                     KKLEINREELVNIIINFKED"
     gene            complement(7493..8152)
                     /gene="deoC"
                     /locus_tag="ACOIAP_002710"
     CDS             complement(7493..8152)
                     /gene="deoC"
                     /locus_tag="ACOIAP_002710"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGZ2639589.1"
                     /translation="MKHILQTVDHTMLKATTTLKDIKTLCDEAVRMNVASVCIPPSYV
                     KSATEYLNGRVNICTVIGFPLGYQTTKVKVFEAKDAIENGAVEIDMVVNISDIKNEEY
                     EKIENEIKEIKSVIGDKVLKVIIETCYLNEYEKIKMCEIVTNSGADFIKTSTGMGTNG
                     ATLEDIKLMKKHIGEGVKIKAAGGIKSISDAEKFIEAGAQRLGTSSICKILNGEKPME
                     Y"
     gene            complement(8179..9723)
                     /gene="murJ"
                     /locus_tag="ACOIAP_002711"
     CDS             complement(8179..9723)
                     /gene="murJ"
                     /locus_tag="ACOIAP_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HGZ2639590.1"
                     /translation="MSRVARAAFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDINSKKGEKEALKFLNNVLNIIVGICIIVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTRILIIGIIFIGITSVMSAFLQIKENFIVVGF
                     GSIPYNIVIIISIVLSTVLGPYVLPVGAVVAMVVQLFFYLFFVNKTKYKYLFYLDFKD
                     ESLIKLLALLSPVFIGVAVNQVNSLVDTTLASTLIKGSIPALTYADRLNGFVTGTFTA
                     SIVSVMYPTLSKLSAENNQKKFTISVKSSVNMIIISMIPISVASIVFAKPVVRIIFER
                     GAFDSRATQMTATALVFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIVSVGVNILL
                     DLALIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIRAIFKSLVSSCVM
                     SFIAYFIYKFIFGILGLGTLNELISLTISVVIGFSVYTLLMILFKVEEVDMILNIAKR
                     KLHLKK"
     gene            complement(10018..10782)
                     /locus_tag="ACOIAP_002712"
     CDS             complement(10018..10782)
                     /locus_tag="ACOIAP_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639591.1"
                     /translation="MKNINKECLIKLLTVMVVLIQIIYLLWKKEIVYYIHPRMIPYLV
                     ISICILLFIALSYIMILTKPKHIYQYGSTKYIILSFLITTLLISYSGLNIDKEKTKVE
                     KYKGKEKYQDKIYEKEEFLDRTLEERIYDEKFDVFDTEIYDFLNLLYTKQSVLKGKEV
                     TYVVFVHYDDSLEKNQFIASRSIMVCCAADMISSGPIVNMNQPPKWKEGEWILLTGKI
                     EYKEQKNSSNKTAFLNYIDAKPIEKPLEEVVYPNFG"
     gene            complement(10923..12479)
                     /locus_tag="ACOIAP_002713"
     CDS             complement(10923..12479)
                     /locus_tag="ACOIAP_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGZ2639592.1"
                     /translation="MSTRIDIVAGFLESGKTKFINEYLRNKQYDDKDNILLIVLEEGF
                     TEYSIPFSSKNYIKIERFKDINCLTKEYLKKCSNLYNYILIEYNGTWNIEEFLDIKLP
                     YSCYLGKIYCLVNADTFDVYFRNIDSMVEQIINSDEFYISGSNSIEKTEKITSYIRAL
                     QPSADIFYIDESGNYKKIFPLSLKLKNLIYRIIKFVIVILFFLLLLGVKIQIIKVQDI
                     NDFNRMFFGIILQAIPFLLIGIVLSSCIQFLVSEEKFIYFASRHKVLSYPIFLFMGCI
                     LPLCDCAMVPITEKFIQKGLKVSHAMTFFCISSSINPIVILATIYAFPENNKVIWIRI
                     LVSIMLSALVGISFYFVEKNKNFSPYKKNKIPLFNNIEYEITKITKKGKKFRFLALGI
                     HIGNEFLRIMMFIIIGAFISTIAQILKMNPAFSGYFTNDYAFLYMFFASVFLSICASS
                     NAFIAKGFTNSLPLMSVIPFMVFGPLLDIKNLIVMSSRFSKKFMTIFIIILLVCYIMY
                     FVFFNMEIKL"
     gene            complement(12480..13409)
                     /locus_tag="ACOIAP_002714"
     CDS             complement(12480..13409)
                     /locus_tag="ACOIAP_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGZ2639593.1"
                     /translation="MIKIDIISGFLGSGKTTFIKKLLSAYYKDKKVVLIENEYGEVGV
                     DGLLFKNENIQVRELYSGCICCSLNTDFTKSLKEVIELFKPDTVIVEPSGVGKLSEVI
                     QNCIPLVKQNLVSINHKFTIVDVMKYSVYLKNFKEFYDDQIKYCDAVLLSRVDVCDEI
                     KVREVISSIQNKYHKKYIVSLEQNLLDETIVNYIMSTKSVVHSENDMHCNCHHNHVVH
                     NADDVFSSWGIKLEKSYKYEYIKEILEQFNSGSFGNIIRAKGIFKCEDGLFYEFSFVP
                     DEIKVIPCNYISSGCICVVGFKPNKEKLERAFV"
     gene            complement(13465..14253)
                     /locus_tag="ACOIAP_002715"
     CDS             complement(13465..14253)
                     /locus_tag="ACOIAP_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGZ2639594.1"
                     /translation="MLSYGFMQRALFVGLCVSIAIPCVGLILVLRKFSMLGDALSHTA
                     LAGVCFGLVVGISPTIGAIMSCIIASFSVSIIGKRMKHNEEIAIAVILSLGVGISGIL
                     SNYIKSSVNINSFLFGSIISISGREFALVIALTILILIIFFKYYYEFMFYAFNEKEAQ
                     KHYVNTRKIDILFTILIGLTISISARVVGALIISSLLVLPVACGLILGKSYKSTLLIA
                     IFLSMLFVLSGLTISYYIGLSPGGAIVILGSITLMIILLYKKRV"
     gene            complement(14246..14878)
                     /locus_tag="ACOIAP_002716"
     CDS             complement(14246..14878)
                     /locus_tag="ACOIAP_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2639595.1"
                     /translation="MEIKDGAFSYTDCNVFKSVNVNINKNELVGVYGENGSGKSTLFK
                     IITKEVKLQSGEIFTFDSLTTSFLGQNDRVMAEGSPLTLMEFLLMYQHKEKSKLFKNK
                     KNVMMLLRKYNMEHYAKKQLKSLSGGQLQKSMILKSIMNHPDIILFDEPLNALDEVNK
                     ISVMDMIMDLHNNGHTILLILHDYEQLKKIADKILICENHTIKCEVLNYA"
     gene            complement(14893..15795)
                     /locus_tag="ACOIAP_002717"
     CDS             complement(14893..15795)
                     /locus_tag="ACOIAP_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HGZ2639596.1"
                     /translation="MKRFVLLFCCSLLLLTGCSFKDVKKTSSNKKLSVYTSFYPMYDF
                     AKKIGGTKVDVKNMTPAGIEPHDFEPTTNDIKGLSNADMFIYNGDNMEHWVNDVIQSL
                     DNRNILIVKASDGIDLMKGEKSSDSMDPHTWLSIRNAKKELEKIKNAFCKKDPDNATY
                     YEKNYYKYASEFDALDSQYKKELLPYKGRSIVVAHQAFGYLCKDYNLKQIAIEGLSPD
                     SEPSPARMAEIIKSAKKNKIKVIFYEELVNPKVAETIAKETGSETKVLNTLEELSDKK
                     IKEGEDYISVMKTNLQNLVYALSK"
     gene            15945..16361
                     /locus_tag="ACOIAP_002718"
     CDS             15945..16361
                     /locus_tag="ACOIAP_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGZ2639597.1"
                     /translation="MNNYLKKHNLKSTEKREAVIKVLENSNVPMTIESIHEKANTIVE
                     MNLSTIYRTITTLCEKNITVLVAIHDGKSYYQLNKHRHEHVLICKECKDIIIIDECPL
                     HELEHKLEDETGFDIIEHKLEFIGICPKCKRTNSRT"
     gene            complement(16836..17720)
                     /locus_tag="ACOIAP_002719"
     CDS             complement(16836..17720)
                     /locus_tag="ACOIAP_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2639598.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVMHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGRVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(18011..18487)
                     /locus_tag="ACOIAP_002720"
     CDS             complement(18011..18487)
                     /locus_tag="ACOIAP_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HGZ2639599.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            18753..19928
                     /locus_tag="ACOIAP_002721"
     CDS             18753..19928
                     /locus_tag="ACOIAP_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGZ2639600.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQDYDYNSMKNTLDNVSDNVNEQLKKLGESVKSSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     SDSDTNNSKNNTSTNNENKDNSQTNENDTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(20009..20812)
                     /gene="proC"
                     /locus_tag="ACOIAP_002722"
     CDS             complement(20009..20812)
                     /gene="proC"
                     /locus_tag="ACOIAP_002722"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGZ2639601.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQETLDRI
                     YANFGINTTKDSKEVTRSSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIVGDDKKIVRTMPNTPALVNEAMSSLSINKNINDEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(20852..21442)
                     /locus_tag="ACOIAP_002723"
     CDS             complement(20852..21442)
                     /locus_tag="ACOIAP_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGZ2639602.1"
                     /translation="MVLNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLT
                     SVATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLK
                     EKTMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYN
                     SEKNNHNWVNYTNKVAKILVVSVPNPFEKSNEVKEA"
BASE COUNT         7614 a         3576 c         2394 g         8454 t
ORIGIN      
        1 ttataactat attgtaacta tttttataat cttaggaaaa tattaattgt aaaattaatg
       61 ttatacaata atatatcgta taattttaat taacataata gttacaacat taaaatttaa
      121 atatgggagt gattttagta tgataagaca aacaccatta gaaaaacgat atgacaagct
      181 aggtcctcat attgtaacag cactcaaaaa acgttatttt gatgcttatt actgtaaaac
      241 tagaaatgaa gctttacaac aaattttaga tttaattcct caaaatcatg ttgtatcatg
      301 gggaggctct gaaacgctta aggaaattgg tgtacaaact gctgttagag agaagggatt
      361 taaagttatt gatagagatt tagcaaaaac tccagaagaa agaacagaaa ttatgcgtca
      421 agcactttta tgtgatactt ttttgatgag tagcaatgca attagtgaag atggacaact
      481 atttaatatt gatggaaatg gtaatcgtgt agctgcaatg atatttggtc caaaaaatgt
      541 tatagttgta gctggtatga ataaaattgt aaaaaatatt gatgatgcaa tacaaagaac
      601 tagaacaatt gcatctccgg cagttgttca gcgttttcaa gatgtcaata caccttgcta
      661 tattaatgga agttgtatag actgcacaag tcctgaaagc gtttgtgcat atatggttac
      721 tacaagaatc agtcgtccag caaaaaaaat aaaagtaata ttggtggggg aaaatcttgg
      781 tttataaaat atacatacat ataaatagct ctataaataa taaaatcata tgaaataact
      841 tattcctaaa agtggtagaa tgaaagccac tctgcaagac tttcatttta ccacttttac
      901 attcttttaa atttatgctt ctatattatt aattattttg attttcataa tttttttgtt
      961 cttcatcaag ttgtttgtag taatctttat tgtagtcagc taaataatct gtgccacctc
     1021 cagtaattac atttaacaat ttcattgcag attcttgatt aacttcacaa acataattat
     1081 caccagattt aacaagctct aatgtaagat taaattcttt tttatttgca gaatcaatat
     1141 ctttcatagt tggatttggc atcatagctc ctagtttagg aggattcttt tttaaaattg
     1201 aaaccatatc agtattgtta acttttaaat ctacagtcac tttatcctta ttattcttta
     1261 tatctgaaat ttcccatgtc atatttttag aatacatttt aaatccctct ttatcttcat
     1321 atataagatt acctaatcct aattttggga aatacttatc tacagcgtct gaatcttgtg
     1381 tttttattgc attaaacata ttatccactt cattttttat cttattatca ttggtacatc
     1441 cagctaatac caatgccgat attgcaaaca ttataataca tatagtaaat ttcttcatta
     1501 aattacatcc ccctatactt ttttttacaa aatttatttt cttttttatc ttttgaaaaa
     1561 gttgtagtaa ttgcgttgtg tggacaagct tttatacatt cgccacatct tatacaatct
     1621 aaactattta cgtctttata tactggtata tcaagcttac attttgcttg acatgctgtg
     1681 caattcgtac atttatcttt atcgatttta aatctatata ttgaaatagg attaaaaaaa
     1741 ctataaattg ctcctaaagg gcatatatat ctacaaaatg gtctataaat catgattgat
     1801 atcaataata tcaatagaag aatgcttaac ttccaactga ataaaaatcc tattgattcc
     1861 cttaaattct catttcctaa aataagtggt attcctccca aaaaggtccc tgatgggcaa
     1921 atccacttac aaaaccaagg atctccacct cctgctacat ttacaatagc aactggcaga
     1981 ataattacaa atattattaa gaccaggtac tttaaatatt ttaaatattt atcaccataa
     2041 acttttttta tctttactgg aaatggtatt ttatatagta aatcttgcac aagtccaaat
     2101 gggcaaagcc aaccacaaac aaatctacca aaaaaggctc caaatgccat taaaaaacca
     2161 acaacataaa atgagaattt atactctctg cttgataaaa ctgcttgtaa tgaacctatt
     2221 ggacatgctc caagcgcgcc tggacatgaa taacagttca atccaggtac acacaatcgt
     2281 ttactttctc ctccatatat agttccttct aaaaatccat ttacatatcc atttgtcaat
     2341 gctgtaaatg caacttgagt aataagcctt atattattgt ttatattaga taataacttc
     2401 ataccttttc tcctaaccaa taccaataca ctctagacaa atcataattg ctttagttaa
     2461 tactgtattt gattctccac gatatgtacc taatacaata aatataaaac taattacaat
     2521 aatagaaatg cctgttttgt tatctttaat aaagttactc actatctttt accattttta
     2581 gcctttcatc aataattttt ttccattctt ccttgctatt tgcacctgtt accttttcac
     2641 ccacaaagtt tccttttttg tccacaaaat atgttgttgg aaactctata gttctcttaa
     2701 aatcagtttt tttaagacct tcagatacag tcaattgttg gtaagtagca cctgactttt
     2761 tcataatatc tttgactaat tctttttctt tatctgaaag accagttttc atatcagttc
     2821 catcaacttc tacaatcaat ccctttatag ctacatttga attattattt tcatattctt
     2881 ttgataaagc ttcaagttct ggcatttcac ctatacatgg cccacaccaa gtagtccaag
     2941 tattaataag ggtaagttct ttacttgaga atacatcttt tgttacctta tttccatcaa
     3001 catcctctgt caccaaatta ttaaaccact cactattatt cttgtttgtt tctaccagat
     3061 tggtttctgt ttttttgtta caaccagaaa ccacacctaa aacaaagata caccctaaaa
     3121 ctaacgtaaa aaaccttttc atacctcaca ctcctataat ttatatagta tataaaatcg
     3181 tcgtttgaaa taaaaataac ttatcttcta taattaaagt cattttattt aataaataag
     3241 agtcaattaa atcaaattgt ataaaagata tacagttaaa atatatttct tttcagacaa
     3301 aatcttatat ctaaataata gattgtaatt cttaagatta tatacatata tttctaaaga
     3361 ttttcttaag aaaaatttag atttcactaa tacaatatac gtacttttaa taatataagc
     3421 ttattaatta gcattatact aattcatttc actatgattt tttgttgatt ttaagctgtt
     3481 taccatatga ataaagtttt tcttgactat atagttacta tatagcttat tatatataga
     3541 gagtaacaaa aggaggtaaa atttatggaa aatttattta caagaaaatt cactactttt
     3601 gaatttctaa aatttgtttc tcctgcaatt atatccatga tatttatatc tttgtacaca
     3661 ataatagatg gcatctttgt atcgacatta gttggttcag atgctcttgc tagtataaat
     3721 attgtactac ctataattaa tcttgtttgt ggatttggaa taatgatggc aactggtgga
     3781 ggtgctatcg tttctatacg tatgggtgaa aatagacaga atgaagccaa ttctacattt
     3841 tcttttatag ttttgttttc attgattgtt gggattttat tcacagtaat ctcatatttc
     3901 tttatcaaag aaatatctat tttgcttgga gcaacaaata agttactacc atattgtata
     3961 acttatggaa aagttatgat tttatgtaca ccattttata ttttaaaatt tatatttgaa
     4021 tactttgcaa gaactgatgg aaattctaaa tttagtttat ttctatcagt cattggtggt
     4081 gtaacaaata taatattaga ttatgtattt attaaatatt ttggaatggg tcttttagga
     4141 gctgcagttg caactgctat aggtattatt ttaacttgtg ttttaggcat tctttacttc
     4201 ttatcgagta aatctacact aaaattaaga aaaccaaaaa ccgattttag acttataaga
     4261 gatactatga taaacggttc ttctgagatg gtcacagaac tgtctacagg agttacaaca
     4321 ttcttattta acatagtagc cttaaaatta gcaggagaaa gtgggcttgc tgctcttacc
     4381 atagtattgt atgctcattt tttaatgaca tcagtctatc taggatttgc tgctggagtg
     4441 tctccattaa taagctataa ttttggtgct gaaaatagtg ataaattaaa agagacattt
     4501 aaacattctc taaaatttat atttgtttct tcccttttag tgtttattgt tgctttagta
     4561 tttgcaccat ttattgttag ggtctttgta aatccagata acacagtatt taagctagcc
     4621 ttgcaaggat taaaaatatt tgcatttgct tttttatttg ttggtataaa tatatttgca
     4681 tcaggctttt ttacagcatt tcacaatgga aaaatttcag ctattatatc ttttagtcgt
     4741 gcctttgttt ttataatcat aggaattata attcttcctc ctatgttgaa cctgactgga
     4801 ttatggctta cagttccatt tgctgaagtc ctaactatat ttatatctat tctatttata
     4861 aaaaaatata aaggtagata taagtactaa aaattaatat ttaaaatcaa catttattaa
     4921 aactaatgaa cctgctttaa aatacaaatt tataaatttg atttttaagc aggttttatt
     4981 ttagttataa taagtcattt gcatactctt taattggtgc ttttctaagt aataaaatta
     5041 taaatattat gcaaataact ataattccta cttttgttcc aaataaaata aacggattct
     5101 gaaatgaata aataattttt tctaaataca atagcatttt atgcatattt ttagttgcaa
     5161 aattaactat ataaattacc attaatatcg gtaatcctat caatatagta atactagtaa
     5221 cttttctaac tctatatgta aaagctccaa gtaatactcc tataaagcct atacatattt
     5281 catttaaaca tatttgtaca aaataattta aataagttag tgatatactt gatgttgaag
     5341 gctctatcag tgctgatata gatgtccaaa tcatatctct ctttagtaaa actgacagtt
     5401 ctatattgta acctgttata atttctataa ataacttcga taaaaaaatc aaaactatac
     5461 ctaaaataga aatcacaaag cttaaaataa ttaaatctat gacaatagct tttatacaac
     5521 tttttctatc tgctcttata cttaaagctc ctgaaaagtc tttatttgct atatttactc
     5581 catacacaaa tagtagtata gttatatatg ttaaaatagg attcacaatc gtggataaat
     5641 tagttttaga tgcttctcca aaaatcttga ggataaacac tggtaaaata ttcataacaa
     5701 ttcccataat cataaatata attatataca atttagtatt tttattaaaa aattttatat
     5761 atggctttaa ttcattcaat tacaattcct ccttcttagt catgttaaca aacatatctt
     5821 gtagccctat gtatcctaca tcaatatttg aatttttaag tattttttca tcattttcac
     5881 taaaatcacc atagtaaaaa taagcaactg tatttccaaa tgcctttttg ggctttatac
     5941 tttttataca ttctaatttt tctaactctt ctttatttcc agtaatataa tgagcttttt
     6001 gttttatgac atcaatttct tcatctataa taatttttcc ctcattcaat attattacat
     6061 gctccagtaa atcatctatt tcatcaatca aatgagttga tattattatt gtccttggat
     6121 tttttatata actatctaaa attatgttat aaaactcttg tctatttact gcatccaaac
     6181 caattgttgg ctcatcaaat atagtgatag ctgaattaga acaaatacct attatatttg
     6241 aaagtatggt tttcatacct cttgacagtt gtttatactt ttttttagta tttaagtcaa
     6301 aatatttgca taattcttct tctaagcctt tatcataatt tttataaaaa ctagaagaaa
     6361 attcaaatac ctgacctact ttaaaatctg gactataaaa ttctttttcc ctgacaatac
     6421 aaacttcttc caaaactttt atatcttctt ttgggttctt tcctaatatt tctatctcac
     6481 cttcattttg aattaactga tttaccatta tatttaataa tgtggttttt ccagctccat
     6541 tcttacctaa taaaccatat atcttatttt tttcaaaatt tagagacata ttattaaaaa
     6601 cattttgttt cttaaaactg tgatataaat tttctatctt aatagaacta ctcatatatt
     6661 aatcctcctt gaaattaatt ataatattaa ctaattcttc tctatttatt tctaattttt
     6721 tagcttcttg aagtagattt tttataaaat tatgtttaaa attttctttt ctggcttctt
     6781 ttataatagt ttttgcccca tctgatacaa acatccctat tcccctcttc ttatataaaa
     6841 tattcttatc aaccaatata tttatacctt ttaatactgt agctggatta attttataaa
     6901 gctttgaaag ctctgttgtt gatggaacct gttcttcttc ttttattcca tttgatagta
     6961 tctcatcttc aattgctcgt gctatctgaa tgaatatagg ttcttcattg tttaatacta
     7021 atttcatagg cttctccttt ctaagttagt taattactca actaactaac tgtaacacta
     7081 tcttatagta taatattaca tctgtcaata cgaaataaaa aaatatatgc aaacttttat
     7141 caaaaatacg tttttataga tactaaaaaa tattatattt aaaatactat atatgtatag
     7201 catgaataaa aaaatccaat aggaaaacct attggatttt ttattcatta atatattaat
     7261 aatatttatc aaatttatac ttaactcatc taatatttta gaatacgcta catacttgtt
     7321 tatatatatt ttttaaatta tactgtaata aatagatatg aaattagtat tatattacac
     7381 tatatatttc gtatctataa tactctattt aaaaattcac tttttttatt atatctattt
     7441 ataatctttt aagttactac ttgttataca gctactagta tatataaaat atttaatatt
     7501 ccattggttt ttcgccattt aatattttac atattgaact tgtacctaat ctttgtgcac
     7561 ctgcttctat gaatttttct gcatcagata ttgattttat ccccccagca gcctttatct
     7621 taacaccttc accaatgtgc tttttcataa gttttatatc ttctagagtt gctccatttg
     7681 ttcccatacc agttgatgtc tttataaagt ctgcacctga atttgttacg atttcacaca
     7741 tctttatttt ttcatattca ttcagataac acgtctctat aattactttt aataccttat
     7801 ctccaatgac actttttatt tcctttattt cattttctat tttttcatat tcctcatttt
     7861 ttatatcaga aatgtttaca accatatcaa tttcaactgc tccattttca atagcatctt
     7921 ttgcctcaaa tacctttact ttagtagttt gataccctaa aggaaaacct attactgtgc
     7981 aaatatttac tcttccattt aaatactcag tagcactttt tacatatgat ggtggtatac
     8041 aaactgatgc tacattcatt cttacagctt catcacacaa agttttaatg tctttcaatg
     8101 tagttgttgc ctttaacata gtatggtcta ctgtctgtaa tatatgtttc ataaaaacct
     8161 cctaagtgta taattaagtt acttttttaa atgcaatttc cttttggcaa tgtttaatat
     8221 catgtcaacc tcttcaactt taaaaagaat catcagtaat gtataaactg agaatccaat
     8281 tactactgaa atcgtcagag atattaattc attaagtgtc cctaaaccca atataccaaa
     8341 aataaattta taaataaaat atgctatgaa actcataaca catgaagata ctaatgattt
     8401 aaaaattgct cttattattt tatcttgccc aaaatatcct acttttctct ttaagtttaa
     8461 aaaaagtaac aatatacatg ctattgatga tgagctagtt gccaacgcaa gacctccatg
     8521 ggccataggt tttatcaaag ctaaatccaa taatatatta actccaactg atacaatacc
     8581 atttaccata ggtgtttttg tatcctgtaa agaataaaaa acttttccta atatgtctct
     8641 taatccaaaa gctgtcatcc caactgcata aaaaactaaa gcagtagctg tcatttgagt
     8701 agctctagaa tcaaatgctc ctctttcaaa tataattcta acaacaggct tagcaaatac
     8761 aatagatgca acagaaattg gaatcataga aattattatc atatttacac tagacttaac
     8821 cgaaattgta aacttttttt ggttattttc tgcacttaat ttcgataacg taggatacat
     8881 tacagatact attgaagctg taaatgttcc tgtaacaaac ccatttaacc tatctgcata
     8941 agtaagtgct ggaatactcc ccttaatcag tgtagatgct aatgttgtat ctaccagcga
     9001 atttacttga tttacagcta cgcctataaa tacaggtgat aatagagcca gtagctttat
     9061 taaactttca tctttaaagt ccaaataaaa taaatattta tattttgttt tattcacaaa
     9121 aaacagataa aaaaatagct gaactaccat agctactaca gccccaacag gaagtacata
     9181 tggtcctaac acagtactta atactattga aataattatt acaatattat aaggtatact
     9241 accaaaccca actacaataa aattttcttt tatttgtaaa aaagcagaca taacactggt
     9301 aatccctata aatattatcc caattataag tattctagtg aattttacag taagtaaaaa
     9361 tctttctccc tcaaatccta tggcaaatat acttacaagt tgttttgaaa aaataactcc
     9421 taatattgct acaattatgc atataccaac tattatattt aaaacattgt ttaaaaactt
     9481 taatgcctct ttttctcctt ttttactatt tatatcttga tacataggaa taaaggtagt
     9541 aactatagca gttcctattg ctgcaaatat aatatttggt atattcatag ctgttaaata
     9601 actttctgta tacaagccag tcccataaat cgaagataac actagttctc tacccattcc
     9661 aagaatttta gatattatag tgactatcat taaataaaaa gctgctctag ctactctgct
     9721 cattttatca ctccactctt ctcgcgtttc ttcataattt ttttagaaga aaagtactta
     9781 tatcagctat atttctaaat accatttttt attttttatc aatcaataat tttaaaagta
     9841 gtggacacag aaaatcacta cttattttca aagtatattc tatcatatat tgttcattat
     9901 gaaaactttt tatcttttgt cttatttctt taggtatttt aaatatataa agactagaaa
     9961 ttttactcca tgtgaaactt ataagcaata acaatgttta catggagtaa ataaaaacta
    10021 cccaaaattt ggataaacaa cttcttctaa tggtttttca ataggttttg catctatata
    10081 attgagaaat gcagtcttat tactagaatt tttttgttcc ttatattcaa ttttacctgt
    10141 taatagaatc cattctccct ctttccattt aggaggttga ttcatattga caattggacc
    10201 actcgaaatc atgtcagctg cacagcatac cataattgaa cgtgaagcta taaactgatt
    10261 tttttcaaga gaatcatcat aatgaacaaa tactacatat gttacttctt ttcccttaag
    10321 aactgactgt tttgtatata gtaaattgag aaaatcatat atttctgtat caaatacgtc
    10381 aaatttttca tcatatatcc gttcttctaa tgttctatct agaaattctt ctttttcata
    10441 tattttatct tgatattttt cttttccctt atacttttca actttcgttt tttctttatc
    10501 tatattcaaa ccactatacg atattagtaa tgttgttatt aaaaatgata aaataatata
    10561 tttagtactt ccatactgat aaatatgctt aggttttgtt agtatcatga tgtaagaaag
    10621 tgctatgaat agtaatatac aaattgaaat tactaaatat ggaatcatcc ttgggtgtat
    10681 ataatacaca atttcttttt tccataataa atatataatc tgaattaata ctaccataac
    10741 tgttaataat tttatcaaac actctttatt tatatttttc ataatcaatc ttaccttttc
    10801 tgaaccctcc cttgactaaa gtcgcaaggt tcctgcttca taaaatttta cataatcaaa
    10861 ctttaagata actgacgtaa ataataaaat ttattcttta ctataaaaag ataaatgcta
    10921 aattataatt ttatttccat attgaaaaaa acaaaataca taatgtagca aacaagtaga
    10981 attataataa aaatggtcat aaattttttg ctgaatcttg atgacattac aattaaattc
    11041 ttaatatcca acaaaggacc aaataccata aatggtatta cgctcataag tggtagagaa
    11101 ttagtaaatc ccttagcaat aaaagcatta cttgaagcac atatagaaag aaaaacagat
    11161 gcaaagaaca tatacaaaaa tgcatagtca ttagtgaaat aacctgaaaa tgctggattc
    11221 attttaagaa tttgtgcaat agtagaaata aatgcgccaa taattataaa catcattatt
    11281 cttaaaaatt catttcctat atgaatacca agtgcaagga atctaaactt cttacctttt
    11341 ttagtaattt ttgtaatttc atattcaata ttattaaata aaggtatttt atttttttta
    11401 tatggagaaa agtttttatt tttttcaaca aaataaaaac ttattcctac aagagcagaa
    11461 agcataatac taactaatat tcttatccat attaccttat tattttcagg aaaagcataa
    11521 attgttgcca atataacaat aggattaata cttgatgata tacagaaaaa agtcatagca
    11581 tgtgatactt ttaaaccttt ctgtataaac ttttctgtaa ttggaaccat tgcacaatca
    11641 cataatggta aaatacaacc cataaataaa aaaattggat aagataatac tttatgtcta
    11701 ctagcaaaat atataaactt ctcttccgaa acaagaaatt gtatacaaga agaaaggaca
    11761 atcccaatta aaagaaatgg tatagcctga agtattatgc caaagaacat tctattaaaa
    11821 tcattgatat cttgtacttt aataatttgt attttgaccc ccaataataa taaaaaaaac
    11881 agtataacta taacaaactt aataattcta taaataagat ttttaagttt taaacttaga
    11941 ggaaaaattt ttttgtaatt accagattca tcaatataaa aaatatccgc agaaggttgt
    12001 agtgctctta tatacgatgt aattttttct gttttttcaa ttgaattact tccactaata
    12061 taaaattcat cactatttat tatctgctca accatggaat ctatatttct aaaatacaca
    12121 tcaaatgtat ctgcattgac taaacagtat atcttcccta aataacatga atatggaagc
    12181 tttatatcaa gaaactcctc tatattccat gtcccattgt attcaatcaa aatgtaatta
    12241 tacagattac tacatttctt aagatattct tttgtcaaac aattaatatc tttaaatcgc
    12301 tctatcttta tatagttttt cgaagaaaat ggaattgaat attcagtaaa accttcctct
    12361 aatacaatta ataaaatatt atctttatca tcatattgtt tattccttaa atattcatta
    12421 ataaacttag tctttccaga ttctaagaat ccagctacta tatcaattct agtactcatt
    12481 taaacaaaag ctctttctaa cttttcttta tttggtttaa agccaactac acaaatacaa
    12541 ccactactta tgtaattaca aggtataacc tttatttcgt caggcacaaa gctaaactcg
    12601 taaaacaaac catcttcaca tttaaatatg ccctttgctc taataatatt tccaaaacta
    12661 ccactattga actgttctaa aatctctttt atatattcat acttatagct tttttctagt
    12721 ttaatacccc aactactaaa tacatcatct gcattatgta ctacatgatt atggtgacag
    12781 ttacaatgca tatcattctc actatgtact acagattttg tactcataat ataattaaca
    12841 atagtctcat ctaataaatt ctgctctaaa gatacaatat attttttatg atacttgttt
    12901 tgtatggaac ttataacttc ccttactttt atttcatcac atacatcaac tctagataac
    12961 aaaacagcat cacaatattt aatctggtca tcataaaact ctttaaagtt ttttaaataa
    13021 acactatatt tcattacatc aactattgta aacttgtgat ttatactcac taaattttgt
    13081 ttaactaatg gaatacaatt ttgtattact tcactcagtt ttccaactcc agatggttct
    13141 acaattactg tgtctggctt aaataattct ataacctctt ttaatgattt cgtaaaatcc
    13201 gtatttaaag aacagcaaat acaaccagaa tagagttctc ttacttgaat attttcattt
    13261 ttaaacagta gtccatcaac tccaacctct ccatattcat tttcaataag tactactttt
    13321 ttatctttat aataagcact tagtaacttt ttaataaaag ttgtcttacc agagcctaga
    13381 aatcctgata taatatcaat ttttatcatt tgcacctctc ccttttattt tttatttgtt
    13441 cttaccttag tctaacgttt ttatttagac tctctttttg tacagaagaa taatcattaa
    13501 tgttatgcta cctaaaataa caatagctcc tcctggacta agtcctatat aatatgaaat
    13561 agtcaatcct gataatacga acaacattga taagaaaatt gcaataagta atgttgattt
    13621 ataacttttt cctagtatta atccacatgc cactgggagt actaataatg aagaaataat
    13681 caaagctcca acaactcttg cagaaattga aatagtaagc ccaattaaaa ttgtgaataa
    13741 tatatctatt tttctagtat ttacataatg tttttgtgct tctttttcat tgaaagcata
    13801 aaacataaac tcataataat acttaaaaaa tataatcaaa atcaatatgg tcaaggcaat
    13861 tactaaagca aactctctcc cactaattga tataatactc ccaaataaaa aactatttat
    13921 atttacacta gattttatgt agtttgatag tattccacta attcctacac ctaatgataa
    13981 aataacagca atagctattt cttcattatg tttcattctt ttacctataa tagaaactga
    14041 aaaagaggct attatacaac tcataattgc tcctattgta ggactaatgc caaccacaag
    14101 accaaagcat acacctgcaa gtgctgtatg tgacaatgca tctcccaaca ttgaaaattt
    14161 tcttaatacc aaaattaaac ctacacaggg aattgcaatg ctcacacata gaccaacaaa
    14221 taaggctctt tgcataaatc cgtaactaag catagtttaa tacctcgcat tttattgtat
    14281 gattctcaca tattaatatc ttgtctgcaa ttttttttaa ttgttcataa tcatgtaata
    14341 taagaagaat tgtatgtcca ttattatgta aatccattat catatccatt acagatattt
    14401 tatttacctc atctagtgca tttaaaggtt catcaaataa tattatatcg ggatgattca
    14461 taattgattt taatatcatt gatttttgta attgaccacc agatagagat ttaagctgtt
    14521 tttttgcata atgttccata ttatactttc ttagtagcat cattacattt ttcttatttt
    14581 taaacaactt tgacttttct ttatgttgat acattagtaa aaactccatc aatgttaatg
    14641 gcgaaccttc tgccatcact ctatcatttt gacctaaaaa actcgtagtt aatgaatcaa
    14701 aagtaaaaat ctctccactt tgtaacttaa cttcctttgt aataatttta aatagtgttg
    14761 atttcccact accattttct ccataaactc caaccaactc atttttattt atatttacat
    14821 ttacactttt aaaaacattg caatctgtat acgaaaatgc tccatctttt atttccacta
    14881 tatttttcat acttattttg ataatgcata taccaagttt tgaagattag ttttcataac
    14941 tgatatatag tcctccccct cttttatttt tttatcagat aattcttcta atgtgtttaa
    15001 tacttttgtt tctgaacctg tctcttttgc tattgtctca gctacttttg gatttacaag
    15061 ttcttcataa aatataacct tgattttatt ctttttagca gatttaataa tttctgccat
    15121 acgtgcaggg cttggttctg aatctggaga caatccttca attgcaatct gttttaaatt
    15181 atagtctttg caaagataac caaatgcttg atgagccaca actatagaac gtcctttata
    15241 tggaagtagt tcctttttgt attgtgagtc taaagcatca aattcacttg catacttata
    15301 ataattcttc tcataatatg tagcattatc tgggtctttt ttacaaaaag cattttttat
    15361 tttctctaac tctttctttg cattacgaat actaagccat gtatgagggt ccatactgtc
    15421 tgaacttttt tctcctttca tcaaatcaat tccatcactt gctttgacaa tcaaaatatt
    15481 tctattatcc aagctttgta taacatcatt gacccaatgt tccatattgt ctccattgta
    15541 gataaacatg tcagcattgc tcaatccttt tatatcattc gttgttggct caaaatcatg
    15601 aggctcaatt ccagcaggtg tcatgttttt aacatcaacc ttagttccac caattttttt
    15661 agcaaaatca tacattggat aaaaactagt atatacactc aattttttgt ttgagcttgt
    15721 ctttttaaca tctttgaaac tacacccagt caatagtaat aaactacagc aaaataataa
    15781 tacaaatctt ttcataatcg ccctcctttt tgcaaatgct ttgcatttgc atttttataa
    15841 ggattatctc atttttttct ctatttgtca actaattgtg ttgttaaatt atatcttatg
    15901 atatatgata ataatagaat cataaaagaa tggtggtttt atatatgaat aattatttga
    15961 aaaaacacaa cttaaagagt acagaaaaaa gagaggctgt aattaaagta ttagaaaata
    16021 gcaatgtacc tatgacaata gaaagtattc acgaaaaagc aaatactata gtagaaatga
    16081 atttaagtac tatttacaga acaataacaa ctttatgcga aaagaatatt acagttttag
    16141 tagctataca tgatggaaaa tcttattatc agcttaacaa gcatagacat gagcatgtat
    16201 taatttgtaa agaatgtaaa gatattatta tcattgacga atgcccctta catgagctag
    16261 aacataaact tgaagatgaa actggttttg atattatcga acataagtta gaatttattg
    16321 gcatatgtcc taaatgtaaa agaacgaact ctagaacata agctcatctc tcttttttat
    16381 ttaacttgtt tttcttatta aatatataat tatagattat ataaagttaa taaggaaaga
    16441 taattgcaag gcttaatgaa attattttta gaaaaagttt ctactaagtc ttgaaatact
    16501 tatatatatt atttcaataa aattttattt ctaagataat aattaaatct ctatttatta
    16561 acttaaattt aaatttattt cttcaaaata aacacttaaa taagctataa ggaataaccc
    16621 tatctgtaat tttagctact agcgaatgat aaaatatatc aattctgtag atacttttaa
    16681 tgtgtattga taaagacttg tttctgttaa acataaaaag tgtgctcctt cctttatatg
    16741 atgatatttg atattttaat tatcaccact tttggaagaa tacacacttt attttaaata
    16801 ccttttgtac tctattttat ataatttcta acaacttaat aaaaatgctt taattgtttt
    16861 aacttacttg gatgtcttaa ctttcttatt gctttagctt ctatttgtct tattcgttct
    16921 ctagtaactc caaataccct tccaatctgt tctaatgtct tagggtcatc atcatcaatt
    16981 ccaaatctca ttcttaaaac ttgctgttct tgctctccaa gacctgtaag caattcttct
    17041 attttttctt ttaaattatg ttgttcaacc tcatgcatca caacatcctt aaaatcagca
    17101 tctgatggta taaattcaac taaactacta tcctcatctt cttttaatgg agtatccaaa
    17161 gatacaacat ttttatctcg tcttaataat tccaatactt tatcaacttc taatccacat
    17221 gcatctgcaa tctcatctat agttggctct cttaataata cattcaaaag ttcttgtttc
    17281 tttttcttta caaaatttat tctctgatga agatgtatag gtatcctaat agtattttcg
    17341 caatcgtcga tatatcttgt tatactttgt tttatccacc aagttgcata agtgctaaat
    17401 ttgtatcctt ttttataatc gtacttttct acagctttta taagtcctat atttcctgct
    17461 tgaattaaat ccaacatatc aatactatct cttttatatc tctttgctat gctcactacc
    17521 aacctataat ttgaatttat aaatttttct tttgctactg aagatgagtt gattatttcc
    17581 ttagccagct ctacctcttc tcctgctgac aacattttgt attcctctat ttcctttaaa
    17641 tacattttca tcgcatttga tacatttgat gaacccacac aaatataatt ttcataatta
    17701 ttttcttttt tagtatccat aatcaaaccc cttctattca tagaatttgc taaaacaaaa
    17761 ataaataatt taaacctaca taagctacaa ttacataata tcccattctt caaatgaatt
    17821 gttttgtata ttatgtatac aaatttataa aaactatacc tataatatta ttctacttct
    17881 aacagcaata tcctccttat atatataatt tattttatta tatgttgtta tattcttagt
    17941 ctttagaatg atatatgtct aaaaaaagac tgtttactaa acagtctttt tttatatata
    18001 tgctcaatat ttaattttca tgatgatgat tacatccaca tccacaattt tcatcatggt
    18061 gatgatgttc ttctaaatct tttacctgtt gttccatttc atgaaactct tttaccatta
    18121 tatcataagt tggaagagct gcctcagtat cgtattcttc acctctccaa tcagcgtaca
    18181 tcatagcatc tccattagtt aaaaccaatc tacctgacat agttatattg tccacttctt
    18241 ctaaaaattc tatttgtttt tgtaaaactt ctccttctaa ctccacatct tcatctaaac
    18301 attgtactat cattacaggt gcataataat cttcttcatc tttaacattt acaacaatat
    18361 ctaaaattcc ttctgcacct tcttcaaact ctgccaactc aacatttgta tcaatcatat
    18421 cttgaggtac taataagtct tctattaaat attttattac tctatctttt actaattctt
    18481 ttgacattta tttttctcct tccgattcta taacattatc ataatcattt ctatattata
    18541 gtatactaca ttaattgttt tttcaatctc ttacaaaaat tatttttttg ttatcttcct
    18601 tatatttcct tttttattac aaagttgtaa tcgcattgat ttaaaaaata gtttatattt
    18661 agtataatag aaatgtaaca catattttta ttcaatatat taataaaaaa tagattgaaa
    18721 atgtaatgta tgttaaatct aggaggaata ttatgaagtt taaaaaacaa attagttcta
    18781 ttgttgtgtc tactatgctt gtacttggaa gtatgaatct ttcttatgca gatggtacaa
    18841 atgtagttac acttggagct aacttatcag agtctcagaa gcagcaaatg cttaattact
    18901 ttggagtaaa aaaagaccaa gtcttagttt tagatgtaac aaatgcagaa gaaagacaat
    18961 atttacaagg tgttgcaaca gagggtcaac ttggaaaagt tactatatct tgttcatatg
    19021 ttgaaccaac taaaaaagga aatggaatta atgttaaaac agcaaactta acttgggtaa
    19081 ctagctcaat gattgcttca acacttacaa cagctggtct tgaagatgca aatgttattg
    19141 ctgctgctcc atatcctgta agtggtactg gagcattgac aggaatcatg aaagcatttg
    19201 aggatgcttc aggaaagaag cttgatgaga cgaagaaaga aattgcttct gaagaattgg
    19261 tggttacagg tgatttagga gacgatatag ggcaagaaaa agcaacaggt gtaatgaatg
    19321 atataaaaac agaaattgta aagaatggta caaaagatac caatcaaata gcaaatacaa
    19381 taaataatgt tgtaaataat tacaatatta ctattacacc agaacaaaaa gaacaaatta
    19441 aaggtgtaat gaaaaaaata gctgaccaag attacgatta taatagcatg aaaaatacac
    19501 tagataacgt atcagataat gtaaatgaac aattaaagaa attaggtgaa agtgttaaga
    19561 gttctggtat actagatact attggtggat ggtttagtgg aataggagac tggttctctg
    19621 gtttattctc aggtggagat aaaaaagatt taggaatctt aaataacact aatgatgagt
    19681 ctcttggctc tgatgctgta ataaattcta cagaaggtgt tcaaataaac ccacaaaata
    19741 atactaattc taacagtgac agtgatacaa ataactcaaa gaataatact tcaactaata
    19801 atgaaaataa agataattct caaacaaatg aaaacgacac aacaaataat tcagaaaatc
    19861 aatcaaataa taatgactca gttggtttct ttgaaaaaat aaaaaattgg ctttcaggcc
    19921 tattttaaaa attaaacaaa taaaaagaat tgcctaaaat ggaaattttc tataaaaggc
    19981 aattctcttt atttacaata aatttttatt actcactcat ttttttagat ttttctatac
    20041 atgcacatat cgcttttatc acagaagctc taaaaccttc ttcttcaagt actttaactg
    20101 cctctatagt agttccacca ggtgaacata ccatatcttt taactcacca ggatgtttcc
    20161 ctgtctcaag taccattttt gcagagccca taacagcctg tgatgcaaac ttatatgctt
    20221 gtggtcttgg cattcctgca attactgctg catctgctat agcttctata aataaaaaca
    20281 catatgctgg tgcagaacca cttgcaccaa ttacagcttc tataagatac tctggaacta
    20341 cctcagtatt tccaaaagaa ttaaatactt ctgtaactgc ttctaagtct tcatcgttta
    20401 tatttttatt tatagaaaga gaagacatgg cttcatttac aagagctgga gtatttggca
    20461 tagttctaac tattttttta tcatctccta caatagactc tatatccttt atagattttc
    20521 ctgctgctat tgtaactata attttattgt catctataaa atcttttatc tcttccaaaa
    20581 tatcatcata tatatctggt ttaacagcca caattactat atcagagctt ctagttactt
    20641 cctttgaatc ttttgtagtg tttattccaa aatttgcata tattctatca agagtttctt
    20701 gactatatgc tgatgctata accatattag gttcaactaa ttttgaattt actattcccc
    20761 ctatcatagc gcttgccata tttcctgcac ctatgaatcc aatttttttc actttagtac
    20821 ctccttatta gctaatagta gttgctaaaa tttaagcttc ttttacttca ttagattttt
    20881 caaatggatt tggtacactt actaccaaaa ttttagctac cttattagta tagttaaccc
    20941 aattatgatt gttcttttca ctattatagt gtattgtgtc tcctggatac atttctattt
    21001 gctcatctcc caaaaacact gtaagagtgc cctctaatac atacacaaac tcctcacctt
    21061 catgtacata acaacaaatt tcctcactac tcttacttgg aagaatttca attaatctcg
    21121 gtaacattgt tttttccttt aaactagatg ataaatgata atgtataaat gttgagtttt
    21181 ctacatcaaa tacttctttt tcataacttc ttaatacagc tcttttatgc tcttttggct
    21241 tcataaaaaa gtaagttaat tctacatcta gtacacttgc tatttttcct aaggaatctg
    21301 ttgccacact tgttaatcct ctttcaagtt gtgataaaaa accaattgac aagtttgttt
    21361 tttcactcat atccttcagt gtcatttgct tttgagttct gagttgcttt atttttgctc
    21421 ctatgtcctt attcaaaacc atcaccccta aataatttta attttttcat aatataaata
    21481 caaaaatata aatataggta ttaaacctac ctttatttca tttttaaaga attttataag
    21541 tattactata atttattaat ctttttttgt ctacattttt acgattattt acgatttatt
    21601 tttcacacat gtatatttaa tttcgccaac taaatatacc ttttttataa gcatctactc
    21661 tttatatata aaacttaagt tattcataca attttcttta gctttagtta ttaaaatttc
    21721 aaattatatt attatttcta cacattatta catcctttag tacaattata acataatttt
    21781 acaatttaat gatatctatt caatgtcttt ttttactcta caacatattt tattttagag
    21841 tttagcacta tatatatttt ttatatacag tcttgtcaat ttttagattg tcaagaatta
    21901 ttgaagtatt ttatgaccat ttaaatttta ttttctaatt ccttacttaa caaaaattgc
    21961 ttatgataaa aaaataatat tatctccata agattcttgt aaatatatct atattctaaa
    22021 tataatttct ttttttgt
//
LOCUS       DBGJFK010000063        21992 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.063, whole genome shotgun sequence.
ACCESSION   DBGJFK010000063 DBGJFK010000000
VERSION     DBGJFK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21992
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.063"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            319..2553
                     /locus_tag="ACOIAP_002724"
     CDS             319..2553
                     /locus_tag="ACOIAP_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2639603.1"
                     /translation="MQNHDYIKMLNKKVKLLSKELDNRNFKLKSSNEIDFFSKMPNRE
                     FMYQYIDDCISKNVHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQKLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELSTMGTTIVESARELKIQLPNEKEIYSNITFSIGGAI
                     WNGESNMTTLMLFNQVYSALKKAKSEGKNRYTLFDFKDNTFYNKLENDKEFLSEISYA
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     YLFEENCRNIRKWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLTELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKQFEKLLSKGNNSEKMFIKYSDIGKALIEKIFDGFFIMQDMKKLEANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEAAEHQ
                     KYSNFYFSANCIISENKLLLSKLHLDLINTAGYINEFESYSIPKMANTHLDESDILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMLDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLEMIDTNKIEPFLYRFIKRDGQIATVMYTQCNLSAIDGRSIAQGMYVDINKIKN
                     LTKI"
     gene            2584..3429
                     /gene="dccA"
                     /locus_tag="ACOIAP_002725"
     CDS             2584..3429
                     /gene="dccA"
                     /locus_tag="ACOIAP_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP diguanylate cyclase DccA"
                     /protein_id="HGZ2639604.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRITFINDNLKNLIKSYMQDNPLG
                     MTNVEIAKKLPDNIAKFFTDYHNIQLNWEKDYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKSYIITMANDITKLYEENKKNLHYSITDPLTGAYNRKYLNDRFDMFIGDYIVL
                     IDLDNFKMVNDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQIEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKKKKKF
                     NKNNY"
     gene            3669..5402
                     /locus_tag="ACOIAP_002726"
     CDS             3669..5402
                     /locus_tag="ACOIAP_002726"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2639605.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQYEIPSCDINNDIFEIVSEYENRCMVLGKYTVRTKENAQMIL
                     EVNQRCTFEIIEDREKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYNEFMEMSGGSAVGAVYPPD
                     LPKALEDCEQCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDMENDNFIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLRGNLHETIEIREINSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIQEYLCSSDSKNND
                     ALLIIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTYDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSVYE"
     gene            5869..6213
                     /locus_tag="ACOIAP_002727"
     CDS             5869..6213
                     /locus_tag="ACOIAP_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2639606.1"
                     /translation="MKNELYLICLNKRFNLWVQPTFVAPFKELLIDNNLRDIKLHKLR
                     HANATLILLSSTNIKSISEILGHADIKITMNRCSHLLYEMDNEASENTIQIMFSFTSI
                     KCQLKHFFLLIS"
     gene            6404..7759
                     /locus_tag="ACOIAP_002728"
     CDS             6404..7759
                     /locus_tag="ACOIAP_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2639607.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISAITNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIIFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATVIASISVFAVCI
                     AFSEPIVSLFIHPEETILFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(7877..8536)
                     /locus_tag="ACOIAP_002729"
     CDS             complement(7877..8536)
                     /locus_tag="ACOIAP_002729"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HGZ2639608.1"
                     /translation="MLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTISEEH
                     GKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAYGDI
                     DIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGEEFL
                     GKKLTRELVEKIKDAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLVKDGYGYLEI
                     K"
     gene            complement(8612..9040)
                     /locus_tag="ACOIAP_002730"
     CDS             complement(8612..9040)
                     /locus_tag="ACOIAP_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGZ2639609.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGIFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            9197..9745
                     /locus_tag="ACOIAP_002731"
     CDS             9197..9745
                     /locus_tag="ACOIAP_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HGZ2639610.1"
                     /translation="MYTNFNIDFNNFNKKENATKFMLMGVLLIILGLLCLTFKTLGIK
                     LISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWILIIACILLFVFPQKIQ
                     SIFSLLLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGICLILSPLFLSRFIVSI
                     MSFFIILFGLVLFFSGNTARKY"
     gene            9865..10800
                     /locus_tag="ACOIAP_002732"
     CDS             9865..10800
                     /locus_tag="ACOIAP_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HGZ2639611.1"
                     /translation="MNKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SIGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVVGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMDVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKSRNSYQGCKFV"
     gene            complement(11102..12046)
                     /locus_tag="ACOIAP_002733"
     CDS             complement(11102..12046)
                     /locus_tag="ACOIAP_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGZ2639612.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLASEQVAFTRLF
                     FGFIVLGIYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIVGVSIAAVL
                     LYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGI
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSKPWEILNYANNLDVLFC
                     MLMLGIVPAALAYIFYATGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSSKLKQIEKTESI"
     gene            12364..13806
                     /locus_tag="ACOIAP_002734"
     CDS             12364..13806
                     /locus_tag="ACOIAP_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2639613.1"
                     /translation="MNLNLELDLEFYKKILEASHDEICVSDDKGIIIYCNKAFEENYG
                     LKKEDILGKNVSFLEDSGYSTKSPIPVVLKTKSKFSLEQDTQTGKKLIITATPIFDEN
                     GNLEFTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVM
                     RPIINTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRANGPFITINCATISPQLL
                     ESELFGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFT
                     PVGSLKNKNVDIRIISATNADLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVE
                     IIKYYFNRYSSDFNLNKTISKEAMETIANYRFPGNIRELQNIIQKILLTCTDNHITIH
                     NLPNILTKNINITNNGNKTHISQINKVITPDSKSINYKNKNFDTLIKEYEKNIILDAY
                     EKFGSSYKVAKHLEISQSKANRLIRKYTNT"
     gene            14006..14590
                     /locus_tag="ACOIAP_002735"
     CDS             14006..14590
                     /locus_tag="ACOIAP_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HGZ2639614.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(14684..15463)
                     /locus_tag="ACOIAP_002736"
     CDS             complement(14684..15463)
                     /locus_tag="ACOIAP_002736"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2639615.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDMVAIEEIEKKGVQFNVATGRI
                     FKQARNIIEESLDMNGYYICENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(15521..16777)
                     /locus_tag="ACOIAP_002737"
     CDS             complement(15521..16777)
                     /locus_tag="ACOIAP_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGZ2639616.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFAESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILRKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEGEAFKLIKPVEEKIKSRVGKYVYTEGDISVSEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVAYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVRKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            17035..17934
                     /locus_tag="ACOIAP_002738"
     CDS             17035..17934
                     /locus_tag="ACOIAP_002738"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGZ2639617.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVGEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            17958..19406
                     /gene="ddlR"
                     /locus_tag="ACOIAP_002739"
     CDS             17958..19406
                     /gene="ddlR"
                     /locus_tag="ACOIAP_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HGZ2639618.1"
                     /translation="MIFSNLKLNDNEPIYIQIKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSDGLIYSISGKGTFVKSKNKSSNTTWSLNWDYLENTYSKK
                     ASELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLKYMTNKGVDISNKDILITNGFTEGFDIVMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFDMLEYNLIKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYECVKKHIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            19489..20271
                     /locus_tag="ACOIAP_002740"
     CDS             19489..20271
                     /locus_tag="ACOIAP_002740"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HGZ2639619.1"
                     /translation="MSKKSKRKKINKLKLTIVITLLFLALLSIYEILFSNPNKKDNVK
                     SQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGKSMPTDEPI
                     SFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEKINLIDDYD
                     AVDEKSMSDNNTSSFCYRTIAGTNVISNHGKGRAIDINPLQNPQVSGNDVTPKVSTVY
                     ADRSSTKFGMIRKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            20297..21484
                     /locus_tag="ACOIAP_002741"
     CDS             20297..21484
                     /locus_tag="ACOIAP_002741"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGZ2639620.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKANGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEELNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIVELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLALEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEGNTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NID"
BASE COUNT         8385 a         2934 c         2996 g         7677 t
ORIGIN      
        1 aacttaaaat taattataaa aaactctaca ttactaacta tgcatctctc aatctatcta
       61 tttatgaaaa aatatgatat aattgcattc aaaaaggaaa gctttcaata tactagaatt
      121 taagcattaa ctaattttat ctaatattat tactaggtta aaaaacattt gtaacatttg
      181 aacaaataac ttaatgtata ttaattttaa atacgtattt aaaattaatt gtttaaatta
      241 tttatagatt aaaatttaaa tacttctagc ataaatacag ttgtcgtcaa aatttaaagt
      301 atcttatgga ggaataccat gcaaaatcat gattatataa aaatgttaaa taaaaaggta
      361 aaactattat ctaaggaatt agataataga aattttaaat taaaatcctc aaatgaaata
      421 gatttttttt ctaaaatgcc aaatagagaa tttatgtatc aatatattga tgactgtatt
      481 tcgaaaaatg tacatatagg aatcatgttg ttaaatattg ataattttaa attatttaat
      541 gatatatatg gatatctagt gggagaaaat ttattaatta ctttaactca aaaactatta
      601 cactttattc cagaatcaaa agggatagtt gcttatttaa aaggagaagg gtttttaatt
      661 gtacttccaa atgtatcaaa taaagaatta agtactatgg gtacaactat tgtagagagt
      721 gctagagaat tgaaaataca gcttcctaat gaaaaagaaa tttactctaa tattacattt
      781 agcattggtg gtgctatctg gaatggtgaa tcaaacatga ctactttaat gcttttcaat
      841 caagtatata gtgctttaaa aaaggctaaa agtgaaggta aaaatagata tactctattt
      901 gatttcaagg ataatacctt ttacaataaa ttggagaatg ataaagaatt tttatccgaa
      961 atatcatatg ctttacaaac taaacaaatt gaagtatttt accaaccact ttataatata
     1021 aaaaataata ctatagttgg atgtgaggct ctcgcacgat ggagacaccc tattaaagga
     1081 cttctcactc cagataagtt tattccttta tttgaacagt ttggtttgat aacagaacta
     1141 gatttatatt tatttgaaga gaactgtaga aatataagaa aatggattga taacaatgat
     1201 gtttttgttc caatttgttg taacttttct cgtcttcatt tttttaatcc taattttcca
     1261 agtatgctaa aaggtattac tgaaaagtac agcgtctcta catcaaattt cagcattgaa
     1321 ataacagaaa atatattaat agaaaataca aatacaatta ttcaacaact aactgaactt
     1381 cgttcctatg gtttttctgt atcaatggac gattttggtt ctggatattc atcttttggt
     1441 atgttgcaaa atctgccttt tgatataatc aaaattgata gaatattttt atctcataat
     1501 ttaaatgatt ttaaaaatac aaccattttg tattctataa taaacattgc aagagctctt
     1561 gggatgctta cagtatgtga aggtgttgaa acagaacaac atgtagaatt tattaaaagt
     1621 ataaattgtg atatagctca aggttattat tatgcaaaac ctatggagtg caaacaattt
     1681 gaaaagttac tatctaaagg taataattca gagaaaatgt ttataaaata ttctgatata
     1741 ggaaaagctt taatagagaa gatatttgat ggatttttta ttatgcaaga tatgaaaaaa
     1801 ctagaagcaa atgttactga agacattcaa tggtttgatt tttacaacaa aactgaaatt
     1861 acatcttttc ctaaagtaat agaacatttt gaaaaacaca ttaaaggtaa aaaattttct
     1921 atcctttaca aaagtataac cccacataat actgaatcag attcattatt gattagtgga
     1981 gaagctgttt tatcagacga agctgctgaa catcaaaaat atagtaactt ctactttagt
     2041 gcaaactgta taatttcaga aaataaatta ctcttatcaa aattacatct ggatttaatt
     2101 aatactgctg gctatataaa tgaatttgaa tcatattcaa tacctaaaat ggcaaataca
     2161 catcttgatg aaagtgatat tttatcacaa ttttattcaa tgttgcctgt aggtataatt
     2221 cgatacgatt tatttggtga tatgattatt acttatatga atgaagaaat gcttgatatt
     2281 ataggttata caaaagaaca gttttttggt gagatgggcg gaaatttaag agcaattgtt
     2341 catccagatg atttagactt tgtttataaa aaaagtttgg aaatgattga cacaaataaa
     2401 attgaaccat tcttatatag attcataaaa cgagatggtc aaattgccac agttatgtat
     2461 acacaatgta acctttctgc aattgatgga aggtcgattg ctcaaggtat gtatgtagat
     2521 ataaataaaa taaaaaattt aacaaaaatc tagtacaaag tattttattt tggagaaatt
     2581 aatatgttta aagaaatttt tttaagaact tttccaggat ttctaattat aagagattct
     2641 aactatagaa ttacatttat aaatgataat ttaaaaaatt taattaaaag ttatatgcaa
     2701 gataatccac ttggaatgac taatgtagaa atagctaaaa aactccctga taatattgcc
     2761 aaatttttta cggattatca caatattcaa ttaaattggg aaaaagatta tccttatgat
     2821 aaaatatcaa attggatttt agaatttaaa aaagatacta caagttattg gaatgtttta
     2881 gaatacaaag tagatgttga tgaaaaatcc tacataatta ctatggccaa tgatataaca
     2941 aaactgtatg aagaaaataa gaaaaatctt cactactcaa ttactgaccc attaactgga
     3001 gcatataata gaaaatattt aaatgataga tttgatatgt ttataggaga ttatattgta
     3061 ctaattgact tagataattt taaaatggta aatgattatg aaggtcataa tgtaggagac
     3121 aagattttat gtgattttgt ttcactttta aataaagaat tgataaattc tacttctatt
     3181 ataagattag gaggagatga atttattgtt atattctcta gtgatgttga caaaaattat
     3241 gtttattcac agatagaagc cttaagagaa aattttttaa aagtattctc taagtataag
     3301 tatctttcat ttagttatgg tgttgataca gtaaaaagaa atttaaaatt gacaatagtt
     3361 gaattggata aaaaaatgta taaaaacaag gaaaaaaaga agaaaaaatt taataaaaat
     3421 aattattagc attgtcattt taaaataaat taaaattagc tttctttttt aaaactttta
     3481 ccttagctta taaatatgta tctatacaag gtattaatat taaatactga aacatatatt
     3541 gtttcagttc ttttttgtta aaattaactt attcaataaa gatatcatag ttcaacaaag
     3601 cttttaattt aaatatattg atgtataata taattaaaat ataatagcaa aaagaaagga
     3661 ggaatatcat gagcatactc ctaaaaaaag cacccaaatt agcaaaacat attataacaa
     3721 gtttttatat aaatcgagat attgatgaag tattaaaata cctttgtgaa aatgttacat
     3781 ggattggacc aggagaacag gaatttctca cttcttttaa tgaaataaaa aattattttt
     3841 atgcaggtca atatgaaatt ccttcttgcg atataaataa tgatatattt gaaattgtaa
     3901 gcgaatatga aaatagatgt atggtattag gaaaatatac tgttcgaact aaagaaaatg
     3961 ctcaaatgat tttagaggta aatcaacgtt gtacatttga gataattgag gatagagaaa
     4021 aattattagt aaaacacatg cacatatcaa acccttatgg tgaaatgcaa cttgatgaat
     4081 actttcccac taaaattgga actcaaagtt atgattattt gcaaagatta ctaaaggaaa
     4141 aaacagaagt tattgaaatg attacaaata atattaatgg tggcttaaaa ggtagcaatg
     4201 atgatagtac atactcattt ttctatgtca atgaaggatt gcccaagata ttaggataca
     4261 cgtataacga gttcatggaa atgagtggtg gttcagcggt aggtgctgta tatccaccag
     4321 acttacctaa agcactagaa gattgcgaac aatgttttgc aaaaggacct acatattcat
     4381 ctgaatatag aatacgaaaa aaagatggaa cattaatgtg ggtattagat tctggaatga
     4441 aatcattaaa tagtgatggc atagtaaaaa ttaatagtat tattactgac ataacccaac
     4501 taaaaaacat agaatctgaa ctaaaattag aaagagaacg atatcgtatt gctttgcaaa
     4561 atattacaga tatcatgttt gagtatgaca tggaaaacga taactttata aaatatcaac
     4621 gtgtagaaat tgacaaaaaa attgaattgg aaaattttga aacaaaaaat tactctaagc
     4681 tattagaatc tggtaaaatt attcaccttg atgatattgg aaaactacta gaagtacttc
     4741 gtggaaatct tcatgaaaca attgagataa gagaaataaa ttcattaact aaaaatgaat
     4801 ggagatggat tcgtgttcaa tgttcagtta tatatgatag tgaccataac cccatcaaaa
     4861 caataggcgt tttaaaagac ataactgaag ataaatctaa attagaaagc ttaattaatc
     4921 aggctcaacg cgacccacta acacaattgt ataatcaaag agtatcacaa aatcttattc
     4981 aagagtatct gtgtagttct gattccaaaa ataatgatgc tctattaatt attgatattg
     5041 atgattttaa aactgttaat gatacttttg gtcatttaga gggaaatgaa gttctagttg
     5101 ctgtatcaaa aatactatta cataacacat atgataaaga catagttgct cgcatcggtg
     5161 gagatgagtt tacaatattt ataaaatcat taacaaagga tttaataata aaaattacta
     5221 atgatatttt aaatgatgca agtaaaataa aagtaaagga caatcataaa ataacattaa
     5281 gcattggtat tgcttttact gatgattcaa ctaaattata taaagattta ttttctaaag
     5341 ctgataaagc tctttattta tcaaaagcag atgggaaaaa ttgttatagt gtgtacgaat
     5401 aaagccattt atatggctaa aaatgaacct ttaaattcaa attcatagtc taacaatcaa
     5461 agagtcaaag ctaatcttat agatagccaa ctagttacta gaaaaaattt aggcactata
     5521 tttattgata ctgctcattt ttccaaagag caaatttata taaaaaatta aacttttatg
     5581 tatgcacaaa tactaatgat aaacattttg ttacaaacat ttatcattag tatgttctat
     5641 cttaaaacaa aatgataatt tatctatata aaaaagtgct ttgttgacag agttcacttt
     5701 tttatataga tagtttaaat atgaatacat gttttatccc atacattttg gttaatataa
     5761 aaccttgtat cttattatat tcattcatct gttcttaaaa tttacatacc acatagctaa
     5821 tataaaacta aaatcacccc tttaattaac tcactttcta catgtatatt gaaaaatgaa
     5881 ttatatttaa tatgcttaaa taaaagattc aacctatggg ttcaaccaac ttttgttgct
     5941 ccttttaagg aactattaat agataacaat cttagggata taaaattaca taaattaaga
     6001 catgcaaatg caactttaat attactttca agtactaaca taaaatctat ttctgaaata
     6061 ttaggacatg cagatataaa aataactatg aatagatgtt ctcatttatt atatgaaatg
     6121 gataatgaag catctgaaaa tactattcaa ataatgttca gttttacatc aattaaatgt
     6181 cagttaaagc acttttttct acttatcagt taaatgtcag taatatatat agtaagatat
     6241 acttataaaa cgtttgaaat cactattcct taataaatgt tataattatt tactatttgc
     6301 tgttgacatt ggtattatac catagtttat catttatatt agaaattaaa ttattaatta
     6361 atagtttcgt aattttacaa cagatttaca gggagtgata ataatggata caaaaatatc
     6421 tataaacgaa aacatgagtc taggtaaaag attttttaaa tacctagcac catctgtagt
     6481 tgcaatgtgg gttttctcac tatatacaat ggttgatgga atatttgtaa gtaaaggagt
     6541 tggagaatta gctttagctg ctgtcaatat atcaatgcct tttattaatt ttatatttgc
     6601 agtttctcta ttattttcaa ctggagcatc tactataatt gcaatttatc ttgggaaaaa
     6661 agatattaag tctgctaacg aagtcttttc atttaactta gtatcaataa ttatattatc
     6721 aataattata ttagctataa ctttttttaa tttagacaga ttagcactat ttttaggtgc
     6781 tacagaatct acaattggta tggttaaaga ttatttagga ataataatat tttttaacgg
     6841 attctttata gtgtcttatt ctttagaagt tataataaaa actgatggct ttccaatatt
     6901 agctactgtt ggtgtaataa tatctgctat tacaaacatc atacttgatt acttgtttgt
     6961 aattgaattt ggatggggtg taaaaggtgc tggtattgca actggtttgt ctcaagtctt
     7021 ttctactatt ttcttcttaa tacatttttt aagaaaaaac tctactttga atttttcaaa
     7081 atttagaatt gattttaaga cacttagaaa aattatattt ataggttttc ctgattcaac
     7141 tactgaatta agctgtggta tagttgtctt actttttaac ttaagtctta ctaaatatat
     7201 tggagaaaat gctcttattt attatagtgt cataaattat ataaatacat tagtacttat
     7261 gactatgatg ggtataactc aaggtatgca accacttact agtttttatt atggtgcagg
     7321 aaatatagat aatgtaaaaa aactattaaa aatggggata aaagccacag taatagcatc
     7381 aatttctgta tttgcagttt gtattgcttt ctcagaacca atagtctctt tatttataca
     7441 cccagaagaa acaattctat tcaatgaagg agttcgtgtc tttaaaatat tctctatatc
     7501 tttcttattg gtaggaatta atgtaataat ttctggattc tttgtatcag tagaaaaacc
     7561 atcaatttct actgttatat ctcttggtag agggcttgta atagttgttt taagtctaat
     7621 ttcaatgata ctaatatttg gtggtcaagg aatatggatg actactattg tttctgagtt
     7681 tatatgtctt attttatcat tagttttttt aaaaaagaat ttttctacat tagactctaa
     7741 tctaaataag gttgcataga tgataagagt ggcaatatat gaaaatatat aaataaaaaa
     7801 tacctattat acaatcttgc aaacattaaa cctttgcaaa tattaggatt atataatagg
     7861 tattttattt atgtaattat tttatttcta aatatccata accatctttt actaaagttc
     7921 cttttacttc atattctaca ggttttttaa atattggacc gtctacgaca aatgtatgat
     7981 actctccatg ttctccacat gggtctgcac cagcatcttt tatcttctcc acaagttctc
     8041 tagttaattt ttttcctaaa aattcttctc ctagatgctt taagtttact tttgttacaa
     8101 cactacaaaa tccactgtct ataaattcat atactaaatc ctctctactc tcttgccata
     8161 atggtaaatc tactttcata ccaactgctt cacatctatc agtatcccat tttctatggc
     8221 tttctatatc tatatctcca tatgcgcata ttgttgctcc catgttttta gcttttatta
     8281 aagccctctc aaaactctct tcatatcctt ctactccaca ctcagcaact aataaaggta
     8341 atcctatatt gctacttact tgtttaagca tattatattc taaattatgt gtccatgatt
     8401 ttccatgttc ttcacttata gttgtcaaga gtgccacagg cttatatcct tttttcaaca
     8461 ttctatttaa tgctaatata ctatctttac caccactaaa tgacattaca aatttttcat
     8521 cagccaattt taacacctct ttcatctaac tttgttttat taacataatt ataccaaatt
     8581 tttgagttgc atagcaaatt atattaaatt gttaattcac tataaaaaat gttcctaata
     8641 tcaaaagtat aacccctatg tatttgtata aatgcattgt ttcttgtccc aaaattacgc
     8701 tatcaataaa aaatccaact aaaacttggg acacaagtgt taatataagt gtatttgata
     8761 ctcctaaatt tggaattgcc tttacagtaa aatatattat tagacctcca aatattcctc
     8821 ctaataacaa cttataatta aaaccattta tagatactag gcactttagg tcacctgtaa
     8881 ctattatact tgccaaaaaa aatattgctc ctacagttaa acttataaat gtggccacta
     8941 atgctgttgt actttttcct agctctccat ttataaaagc ttcaagagct gtcgaaccac
     9001 ctgctaataa tgcaaatatt attgcccata attttgtcat ggacaaacct ccttctatat
     9061 aattctatta tattaataga agtttatgat acaacctatt aattaattac taagtatagt
     9121 ttaattttta tacactaggc tttatttgga tatgaatttc tgttataatt gttctatcga
     9181 ttttggaggt gattttatgt acacaaattt taatatcgat tttaataatt ttaataaaaa
     9241 agaaaatgct actaaattta tgttaatggg agtattactc attatattag gattattatg
     9301 ccttacattt aagacattag gtataaaatt aatttcttgg acttttggta ttgcactttt
     9361 attctttgca tatttaaatt taaaaaatat taatgaacta aaaagatatg ctactaaaga
     9421 agaaattaaa ccctctatta atattcaatg gattctaata attgcatgta tattactttt
     9481 tgtatttcct caaaaaatac aaagcatatt ttcattatta ttaggatttt atttaatctt
     9541 taatcaacta gtagcacttg taaatagcaa gaataatcct tattctaaat ttacaacttg
     9601 gaatatagtt aagattctat ttggtatatg ccttatatta tctccacttt ttttatctag
     9661 atttatagtg tcgataatgt cttttttcat aatattattt ggactagttc tattcttctc
     9721 tggaaatact gcgagaaaat attaattatt ttctcgcagt atttttatat tgcttaaaat
     9781 agaatttgtt taagttattt atttatggta atatgttttt tgtacaatct cattgtacaa
     9841 ttttattaga aataggtgat ttttttgaat aaatttaaat atgcttttga taataaaagg
     9901 tatcatactt ggaattacta tcttagaaat acttttggag aaaaagtttt taaggtatct
     9961 ataaatgcag gatttacttg cccaaacatt gatggaagta ttggttatgg tggatgcaca
    10021 tattgtagca aagaaggttc gggtgatttt gctggaaatc ctaaagataa tcttatcagt
    10081 cagttttata atataaaaga aatgatgtta aaaaaatggc ctcatgcaaa atatattggc
    10141 tactttcaag cctatacaaa tacgtatgct cctcttgaag ttttaaaaga aaaatatgag
    10201 actatattag aacttgaaga tgtagtaggt ctttcaatat ctacaagacc tgactgttta
    10261 ccagatgatg ttgtagaata cttatctgaa ctaaataaaa gaacaaactt atgggttgaa
    10321 cttggacttc aaacaattca tgattccaca tctaaaatta taaatagagg tcatgattat
    10381 aaaacatttg ttgaaggtgt tgaaaaatta aagtctaaaa atataaaggt tgttgtacac
    10441 attataaatg gtctccctgg tgaagattat aatatgatga tggaaacagc aaaggcagtt
    10501 ggtaaaatgg atgtagacgg cataaaaatc catctattac atgttataaa agatactcct
    10561 atggaaaaga tgttacaaaa tggtatgtta actcttatgg aacaagatga atatatcaat
    10621 cttgtctgcg accaattaga aatacttcct gaaactatga taatccatag actcactggt
    10681 gatggtaaaa gggatgaatt agtaggtcct atatggagcc taaaaaaatg ggaaatttta
    10741 aatcaaattg atgacacctt aaaatctaga aattcttatc agggttgtaa gtttgtttaa
    10801 tactaaataa ttattacaaa taaaacaata tctacaaaat aataactata gaaataatta
    10861 tataaatata attatttcta tagttattta gcctttgcaa agcaaaatat taatttgtat
    10921 atttacacaa taataataaa aaatagataa tctaaactgt agatacttat attttatttg
    10981 tattgtccac tttattctat aaactttata aacagttatt tttttatact aaatataatt
    11041 tggtataatt tttgttagac tctacagtgt ataccaataa ataattttta agtatctagt
    11101 tctaaatact ttcagttttt tcaatctgct ttaacttgct agacttataa aatattctta
    11161 tttcatcata agaaagatta agtgctacta ctgcagatat caacatcaac atcactccaa
    11221 ataactttcc taaggaaaaa ctttctccta atatagtgca accaattatt actgaaccaa
    11281 ccaactctac tgatgccaca acacctgcaa cggataactc tactccttta gagatacctg
    11341 ttgcgtaaaa aatatatgca agtgcagctg gaacaatacc taacattaac atacaaaata
    11401 aaacatctaa attattagca taattcaata tttcccaagg ttttgaagaa ggaatcataa
    11461 atatagctcc aaataagaaa ctgtatacta atattgttga acttgaaaat tcctttaaag
    11521 catttttact aatagtcggc ataagtgcat atgctattgc tgataatatc ccaagtaaaa
    11581 gtccaaaagc gtttaaacct tgaaaatcca aacgtccacc agtcactgcc ataatggcgc
    11641 caataaaaca aagaataagt gaaaataatt tacttctagt aatattttct ttataacata
    11701 cttttgagaa tattgctaaa aacaatggtg atgtatatag taaaactgct gcaattgata
    11761 cacctacaat gtcaattgct ttaaaataac ataaattaaa cattgcctga catataatac
    11821 ctattattac tgaatatata attccttttt tgcttatttt taagatttgt ggtgttctta
    11881 tagatgaata tattcctaaa actataaatc caaaaaataa tcttgtaaat gccacttgtt
    11941 ctgatgccaa tccatttccc attaaaaact ttccaaataa tccaagtgta gcccataata
    12001 accctgctat tgctataaat acataccctt tacttttttc tcccatttta agttcccttc
    12061 tatttttatt tagtcaattt acactattct ttttaagcaa aatttatgcc atcttaaacc
    12121 aatatattcc gactctaaaa ccctagtctt tccaacaata ctaataaaac ttcaattttt
    12181 ttatatttat ttttcactta ctttaagttg atttagactt attttaattg taaaatgagt
    12241 tatatataac ttatttaaag ttaaaataga ctgaaattta tatataaatg tcaaatttta
    12301 agtatattaa tcaattaaac ttattttaat atatcattaa aaggttagga ggaaaataga
    12361 aaaatgaatt taaatttaga attagatttg gaattttaca aaaaaatatt agaagcttcc
    12421 cacgacgaaa tatgtgtctc tgatgataaa ggaataataa tatattgtaa taaagcattt
    12481 gaagaaaatt atggtctgaa aaaagaagat attttaggaa aaaatgtttc ttttttagaa
    12541 gactctggat attcaacaaa aagccccata ccagttgtat taaaaacaaa atctaaattt
    12601 tcactagaac aagatactca gacaggaaaa aagctcatca taactgctac ccctatattt
    12661 gatgaaaatg gaaacttaga atttactgtt gaaaattgta gagatataac tgaacttaat
    12721 aatataaaaa ataaacttga agacacaaaa aaacaagtaa aaaaatataa atctgaagta
    12781 gaaacactat acagaactgc tcttagaatt gaagatactg taattatgga tggaatagtt
    12841 atgagaccaa tcataaacac agtaaatcat gtttctaaaa cggatgtaag tgtactttta
    12901 ttgggtgaat ctggaacagg aaaaagctca cttgctagat atatacacca caacagcaat
    12961 agagctaatg gaccatttat aacaataaat tgtgcaacta tatctccaca acttcttgaa
    13021 tctgaacttt ttggatatac ttcaggtgct tttacaggtg caagtactaa aggtaaagtt
    13081 ggtctcgtag aattagctaa tggaggaact ctttttttag atgaaatagg agatatacca
    13141 caaaatctac aggcaaaatt tttgcaatta atacaggata gaacttttac tccagttggg
    13201 agtttaaaaa acaaaaatgt cgatataagg attatatctg ctacaaatgc tgatttagtt
    13261 tcaaaagtaa aagaaaaaaa atttagagaa gatttatact atagattaaa cgttatagaa
    13321 ataaaattgc ctcctcttag agaaagaaga gataatctag tggaaattat aaaatattat
    13381 tttaatagat actcaagtga cttcaaccta aataaaacta tttccaaaga agctatggag
    13441 actattgcaa attatagatt cccaggtaat ataagagaat tacaaaatat aattcaaaaa
    13501 attttactta cttgtacaga taatcatata acaatacata acttaccaaa cattcttaca
    13561 aaaaatataa atatcaccaa taatggaaat aaaacacata tatcacaaat taataaagtt
    13621 attacacctg actcaaaatc tattaattat aaaaataaaa attttgatac cttaattaaa
    13681 gagtacgaaa aaaatataat tttggatgct tatgaaaaat ttggtagttc ttataaagta
    13741 gccaaacacc ttgaaatttc acaatctaaa gccaataggt tgattagaaa gtatactaat
    13801 acttaatttt aaatttgata aataaaaact taacactatt tacatattgt aaatttggct
    13861 atttattggt attatgaata tggttgaaat tatttaaata aatcctattg acttagtttc
    13921 atatatttac cattaaactt ttatcataaa tatcatatca taataatata tttaataagt
    13981 ctaataaact atacgaggtg taaatatgtt aatgaatacc cattttatta tggcaaaatc
    14041 aatacttgat aatatagatg aaaataaaac attctttata agcgaaaaaa attttatata
    14101 tggtaatata aagcctgatg ctttttctaa atataaatta aaaaaacatt atttagatga
    14161 gtcatttaat atgattgttt ctaaaataaa ctatctatgt agtcttaata tagatagtct
    14221 ttctaaatac ttttcagtaa gtagacttag tcaggaacta ggagtcatat gccatttttt
    14281 atgtgatttt ttctgtgtag ctcacagtga acgttgggaa tttaaacaca gtttaaataa
    14341 acatgttact tatgaaagag aacttggagc atttgcaaaa gatgttgatt tatctaaaat
    14401 taaatgtggt actataaata gtagctttga gaagtttttt actaaacttt atagtgacta
    14461 caaaaagaaa actgattata tgaatgattt aaaattttca gcttatactt gtaatagtgt
    14521 cataaattat atacttgact ctatcttgtc taatacaata aaatcatatc atatagcaaa
    14581 ttgtggttaa tttaagaatt tttaaactta caattgaata taattaaaat gactgctcta
    14641 tagaatataa ttttataatt ctctagaaca gtcatttttt atattaacta tttatctcca
    14701 ttataacatc tatagcactt tttacactat ctactacata atttgcactt tgctttacat
    14761 cttcccttgc cttagacatt gcaaaactat atttaaatcc ttctaacata caaatatcat
    14821 ttggagaatc cccaatagta gcaacttcat ctggacttac atttaaagtt tttattacat
    14881 gctctatact tccccttttt gacacacttt taggaactat atttaaagta tatgttccag
    14941 aaaaatatat ttctaatact tcactaaact cgctttttag ataaagttct attctggata
    15001 attcctccaa attttcagaa catactccta tatttcctat aaggttatca aaactacttc
    15061 ttttttcaaa atctgggtca actataaaat cactagaata atgtctaaaa gcagtggtat
    15121 cactacccac aattacatca cccttatatt taaaataaag ttgtgcatca cttgactcaa
    15181 atctatcaat gactttttta actaaattat catctatcgt tcttttaaaa ataacattat
    15241 aatctttatc atatataaat gaaccatttt cacatatata atatccattc atatctaaac
    15301 tctcttcgat aatattacga gcttgtttaa aaattctacc tgtagcaaca ttaaactgta
    15361 ctcctttttt ttctatttct tcaattgcta ccatgtcctc ttttgttata gttccatttt
    15421 catataaagt tccatctaaa tcacaaaata tatgttttat cataaattaa aagcctccaa
    15481 aaacaatttt atattatact aatattttaa tcaaaataac ttaaagcttt tctaattgta
    15541 ttctcaattc gttaagtaaa tctctagtag ctcttaatct tatctttctt ctatctccat
    15601 taaatatatt tttccttact attgtttttc catttatata tattgcagta taaactagtc
    15661 ctacaggctt ctctttagtt cctccaccag gtccagctac tccagttgta gatataccta
    15721 tattagcttt aagtccttta gcaacgccct cagccatttc tattgctgtt tgctcactta
    15781 ctgctccaaa ctcttccaaa gtttctcttt ttactcctag tcttttcatt ttagaatcat
    15841 tagaatatgc tacacaacct tcaagaaata cagaggatat acctggatag tttataagag
    15901 atgaagaaac caaacctcca gtacaagatt cagccactgc tattgttaga tttttttcta
    15961 cgagtaactt agaaacagca tcttctaatg cagtctcccc ttctgatact gaaatatctc
    16021 cttcagtata tacatatttg ccaactctgc tttttatttt ttcttctact ggttttatta
    16081 atttaaaggc ttctccttca ttttcagcct ttgcagttat tcttattgta acttctaatt
    16141 cttttgcata taaagcaact gttggattag tctgctcatt aattatatcg agaatttcta
    16201 attctagatt tgactcacct attccatata atcttaaagt cttagatact agcatttcat
    16261 ttgtaaattg ttgtaagtaa ggtttgacac tctcattaaa catagctttc atttctcttg
    16321 gaggtccagg taatactatt ataaatttgc catcttttct taaaattgcc cctggtgctg
    16381 taccattatt attttttagt actatagcat cttttggaaa gtacacttgt ttcatattat
    16441 tttcggccat tttttttcct gttttaacaa agaaagattc caaaacctct agtgatggtt
    16501 tatgtagttc taatttctga ccaaagtatt ctgccgcagt ttcttttgtc atatcatctc
    16561 cagttggtcc aagaccacct gtagtaatta caaaatcact tctctttagg ctttcagcaa
    16621 aacattctaa aagtctttgt ttattatctc caacagtact ctgatggtat acttctattc
    16681 ccaatgatgc aagttcttta gctaaaaatt gagaatttgt atttactata tctcctaata
    16741 atatttctgt tcctacactt attatttcag ccttcaaaat ttatcactcc ttgatttata
    16801 gccattaaga ctagtcttaa gttcataaca ataattttag caaaaataat aacataaata
    16861 aagttaaaaa atcatttaaa catatcttta aactagagta ctgctctaaa accacacata
    16921 atacaaactt cgtatatagt ggtactttca tcgtcaactg ttaattcata taattaagta
    16981 tgtaaataaa aaatttactt taaaataata aaaatcaaaa taggagtgta taatatgaaa
    17041 atagcagtta taatgggtgg aatatcatca gagagagaag tttctttaaa ttcaggaaaa
    17101 gagatatata ataaccttga taaaaataaa tacgaagttg taaaagtaat tatagatgat
    17161 aaaaaagata tatttacaaa gataccagaa gatatagatt ttgcaatact tgctttacat
    17221 ggaaaatttg gtgaagatgg atgtatacaa tcaatacttg aaactatgga tataccatat
    17281 tctggatgtg gacctctttg cagtgggatg tgcatggata aaaacataac taaaaaaatg
    17341 cttagagatt caaatctacc tactgctcca tgggttctag taaaatcagt tgatgaaata
    17401 gactatgatg aaatagataa tataggctac ccagtattta taaaaccaaa ctcaggaggt
    17461 tcaagtgtag ccacattctt tattcattct aaggatgaag ttggagaagc agttagaaaa
    17521 ggtctggaag ttgatgaatt tgtaatgatt gaaaaatata taccaggtgg agaatatact
    17581 tcattcatat taaatggaga agtattccct acaatctcta taaaatctga ttcaggattc
    17641 tttgattatg aagctaaata ctcagttgaa aaaggtgcaa aagaggaagt tgtttactta
    17701 gatgaagaac ttcaaaaaag agtaaacgaa atttctgaga cttgttggaa aatttttaat
    17761 tgcaaagcat atgtaagagt tgatatgatt ataagtgaag gtattccata tgttcttgaa
    17821 ctaaatactc ttcctggaat gactcaaact agtttaattc ctagaagtgc tgctgctaga
    17881 ggtattaagt acagtgaact attagataaa cttatagaat actctttaaa ttagatgaaa
    17941 taatttgagg tggtaatttg atattttcaa atctaaaatt aaatgataat gaaccaattt
    18001 atatacaaat taaaaattat ataagtgata tgatatcaaa aggactaatt ccagacaata
    18061 gtaagctccc ttctacaagg gagcttagtc agcttttaca agttagccga aattctgtag
    18121 ttttgactta tgaagaatta aaatcagacg gattaatcta ctctatttca ggaaaaggta
    18181 catttgttaa atcaaagaat aagtcttcaa atactacatg gtcattaaac tgggattatt
    18241 tagagaatac atactctaaa aaagccagtg aattggatat tataaaaagt gaaattcctt
    18301 ggagttctga cctaatttcc tttaaaagta tttctccaga cggagattta ttcgacatgg
    18361 aagaattaaa aaaatccttt ttaaatagaa tttcactaga aggacataaa ttactcaact
    18421 atggatatgc acaaggttat aagcccctta ttgactattt actaaagtat atgacaaaca
    18481 agggtgttga tataagtaat aaagatatat taataacaaa tggattcaca gagggttttg
    18541 atattgttat gtcatctttt acccaagaaa aagactacat aatatgtgaa aatcctactc
    18601 ataatacagc tataaaaatc atgaaatctc ataatctcaa tatcttaggt gtagatataa
    18661 atgaagatgg tttggacttc gatatgctag aatacaactt aattaagtac aaaaataaaa
    18721 taaagtttgc atacattaca ccctcttatc acaatcctac agggattgta atgactcctg
    18781 aaaatagata caaattttat aatcttatga aaaaatacaa tatagcaatt atagaggatg
    18841 gatttaatga agaattactc tacaatagct ctcatatatt tcctatctgt tccctagata
    18901 atatgaataa tggcgttgta tatattggta gtttttcaaa aattttattt cctggaatga
    18961 gaattggatg gatatttgca gataaaaaag taatcaataa gctagaaagt gtaaaaaggt
    19021 gtagaaacat acacgtatcc tttttagacc aaggaatttt atttgattac ttaagtaatg
    19081 gaggttttga aaaatacatt aaaaaaatac gtaaattcta tggagacaaa tttaactttg
    19141 catatgaatg tgtaaaaaaa catataaaaa cagaatacat cttgggtgat ggtggtttgc
    19201 atatatttat aaaactaaaa aatatagata ctagagttct attagaaaaa tgttatgaaa
    19261 aaaatgttat atttatgcct ggagatttat tttttacaga taactctggt tttgatactt
    19321 taagacttgg attttctagg ttgtctttcg aagacattga aattggaata aaaataattg
    19381 gagaaactat aaatgaaatg ttctaggtta actaaatatt gttagcctag tttattttta
    19441 tgatgtataa tatatatagt ttatatgaat ctaatactgg gggataatat gagtaaaaaa
    19501 tcaaaacgaa aaaaaattaa taaattaaaa ttaacgattg taataacttt attatttctt
    19561 gctttattat ctatatatga gatactattc tctaatccca acaaaaaaga taatgtaaag
    19621 agccaagaaa ctatgcaaaa taaaaataat acaacagatg attctaaaaa taatcaaagc
    19681 tctaccaaaa agcaggaaga taacaatatc aagcctactt tttcatattc ttcaatacca
    19741 gataatataa aaaataaaat gattggtaaa tctatgccta ctgatgagcc tataagcttt
    19801 gatagtctat cttatttaaa acttacatac tatggatttg atgaaaaaac tcatcaagga
    19861 gaaatgatag taaacagtga gctagctcca gaagtagtgg atatttttaa ggaattatac
    19921 gaaaaaaaat atccaattga aaaaatcaat ctaatagatg actatgatgc tgtagatgag
    19981 aaatctatgt ctgataataa tacctcatca ttttgttata gaactatagc tggtacaaat
    20041 gtcatttcaa atcatggtaa aggtcgtgct atagatataa acccattaca gaatccccaa
    20101 gtttctggaa atgatgttac tcctaaagta agtacagttt atgctgatag gtctagcaca
    20161 aaatttggaa tgataagaaa aggtgatgat tgttataatg cttttgtaag cagaggttgg
    20221 agttggggtg gatattggaa aaacccagat tatcaacatt ttgaaaaata atagattaga
    20281 aataaaggtg aattatatga atttaatgac attggaaaac ataagtaaaa gctattctga
    20341 aaaaaaatta cttgaaaata tatctcttgg aataaatgaa ggagaaaaaa taggacttat
    20401 tggtgtaaat ggtactggta aatctacctt actcaaaatt attgcaggag ttgaagaaag
    20461 tgaaactggc aatataacaa aagctaatgg tattcggata gaatatctac ctcaaaatcc
    20521 aacttacaat gagaattcaa ctgtacttga acaagtattt aatggaactt ctgaagaatt
    20581 aaagctactt ggtgaatatc aagaaattct agaagaactt aattcaaact ttacagagga
    20641 attaaataaa aaattattat cggtacacga gaaaatagat gccttaaatc tttgggattt
    20701 agaaagtgaa gctaaatcag tacttacaaa gcttggtata aatgacttta atcaaaaaat
    20761 agtagaactt tctggtggtc aaagaaagag agtctctctg gcatcagccc ttattacacc
    20821 ttgcgagttt ttgatactag atgagcctac aaaccaccta gacaatgata ctatagattg
    20881 gcttgaagaa tatcttaatt caagaaaagg ttcattgctt atgataactc atgatagata
    20941 ctttttagat cgtgttacaa atagaattat tgaactagac aagggtagat tatttagtta
    21001 tgatgggaat tattcaatat ttttggaaaa gaaaatggaa agacttgcgt tagaagcaag
    21061 tattgaagac aaaagacaaa atttaataag aacagaactt gcttgggtaa gacgaggagc
    21121 tcaggctcgt agcactaaac aaaaagctcg tttacaaaga tttgacgaac ttataaatag
    21181 ggactctttt aaacctgatg aaaatctcga tatatctgtt gcatcaagta gacttggaaa
    21241 taaaataata gaaatacaca atatatctaa atcatttgaa ggaaatactg ttatagataa
    21301 tttagaatat actttaactc gtacagatag aattggcata ataggaaaaa atggtatggg
    21361 taaatcgacc cttataaaca tacttaatgg agaaatagaa cctgacagtg gatatatttc
    21421 aattggagaa acagttaaaa taggttgttt ttctcaagac gactctcata tgaatattga
    21481 ttaaaaaata gctacgcaca ctcgtgactt tagtcatgaa ttagtagcta aaatagtcag
    21541 catataggga aacttatatg tagagatagg ataacaccta tccaatacta cttgaattgc
    21601 tggaaacccc taaagctaac caaactaaaa cataaggatg aaataaacct aagtgtgaaa
    21661 gttgcgaaag tagaaaaaat tggttagatg gtataaggtt aaatcctaag tactttaaaa
    21721 tgggcaatca gcaggtaagc tccgaatagg agaaacttca acgactattc ctcttgaggg
    21781 aagtacacta caagctattg gtagtggaag tgggtagacc ttaacggata atgccgaagg
    21841 ataagatata gtctgtgctt gcatgaaagt gtaagaagtt cataagagaa ctgcataggt
    21901 agtagcgaac ttatgtgaac gacaacctca aaaatgataa aagttaagaa ttacggttct
    21961 taaatatgtt atttaaaatt aaatataaaa cc
//
LOCUS       DBGJFK010000064        21972 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.064, whole genome shotgun sequence.
ACCESSION   DBGJFK010000064 DBGJFK010000000
VERSION     DBGJFK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21972
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.064"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            122..1486
                     /locus_tag="ACOIAP_002742"
     CDS             122..1486
                     /locus_tag="ACOIAP_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HGZ2639621.1"
                     /translation="MDIKELVKIQRKYCNTGKTRDISFRIEQLKKLKSVVSQNEEKIL
                     LALKRDLDKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSIVKDIIENAFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIVMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDKKNELIEKIKYYTNKYFGDNPS
                     ANEQFPKIINQRHFSRILSLIDKDKVIYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKILEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKIL
                     KKIM"
     gene            1625..2791
                     /locus_tag="ACOIAP_002743"
     CDS             1625..2791
                     /locus_tag="ACOIAP_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGZ2639622.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAMF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGILLTYATAMLIL
                     YLFMYFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIVGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVLFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVEGKLDKKGLPTDTSDYM"
     gene            2908..3690
                     /locus_tag="ACOIAP_002744"
     CDS             2908..3690
                     /locus_tag="ACOIAP_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2639623.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQTSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMVYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYAESLHVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3809..4462)
                     /locus_tag="ACOIAP_002745"
     CDS             complement(3809..4462)
                     /locus_tag="ACOIAP_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2639624.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4486..5850)
                     /locus_tag="ACOIAP_002746"
     CDS             complement(4486..5850)
                     /locus_tag="ACOIAP_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HGZ2639625.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSIFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLSAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKDATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            6499..7929
                     /locus_tag="ACOIAP_002747"
     CDS             6499..7929
                     /locus_tag="ACOIAP_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2639626.1"
                     /translation="MSSQESKPKGNFISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAIAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIGDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            8032..9135
                     /gene="hisC"
                     /locus_tag="ACOIAP_002748"
     CDS             8032..9135
                     /gene="hisC"
                     /locus_tag="ACOIAP_002748"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HGZ2639627.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAMEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKEEPSIG"
     gene            9168..9386
                     /locus_tag="ACOIAP_002749"
     CDS             9168..9386
                     /locus_tag="ACOIAP_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGZ2639628.1"
                     /translation="MNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAHVEVDES
                     KCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            9403..10452
                     /gene="vorB"
                     /locus_tag="ACOIAP_002750"
     CDS             9403..10452
                     /gene="vorB"
                     /locus_tag="ACOIAP_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HGZ2639629.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREEDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RISENEQQWEDYQIEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            10454..11194
                     /locus_tag="ACOIAP_002751"
     CDS             10454..11194
                     /locus_tag="ACOIAP_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HGZ2639630.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSANGRDISTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWSV
                     SLEKSIKWMEEEIVPYYTLGEFKQRDGE"
     gene            11197..11736
                     /locus_tag="ACOIAP_002752"
     CDS             11197..11736
                     /locus_tag="ACOIAP_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HGZ2639631.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENIA
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNIQNEAAFMEGYNNAI"
     gene            11860..13959
                     /locus_tag="ACOIAP_002753"
     CDS             11860..13959
                     /locus_tag="ACOIAP_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HGZ2639632.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKDTDRVYYVN
                     PKREELFGRKCYKTIQEVPEIVDCVVVCTPRNVVPSVLKDSAELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDNYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPTNSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDSSVGFTMVGANIRDEE
                     NEMHETLCQAVSEAREQGLKKPVFAVPTLEGNRYLDYRNRLEYNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(14226..14741)
                     /locus_tag="ACOIAP_002754"
     CDS             complement(14226..14741)
                     /locus_tag="ACOIAP_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HGZ2639633.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YSAPTNPPVTI"
     gene            complement(14833..16044)
                     /locus_tag="ACOIAP_002755"
     CDS             complement(14833..16044)
                     /locus_tag="ACOIAP_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGZ2639634.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIKEIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVAFIKELSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTVSASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            16702..18144
                     /locus_tag="ACOIAP_002756"
     CDS             16702..18144
                     /locus_tag="ACOIAP_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HGZ2639635.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGSI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPSETKQRLKNVKKIY
                     IIGKELSISKSVENELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSVAQNNGDSSTKGDSPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            18186..18539
                     /locus_tag="ACOIAP_002757"
     CDS             18186..18539
                     /locus_tag="ACOIAP_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639636.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFVTDIFNLADVQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTSWILSLIVSLLTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HIAAKFYYKIKTFKN"
     gene            18729..19550
                     /locus_tag="ACOIAP_002758"
     CDS             18729..19550
                     /locus_tag="ACOIAP_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HGZ2639637.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNIPVPSKAYFKGLSKEDAYYKYFNSILETNREFRDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDIIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFINIEKVKSNNIA"
     gene            19808..21691
                     /locus_tag="ACOIAP_002759"
     CDS             19808..21691
                     /locus_tag="ACOIAP_002759"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGZ2639638.1"
                     /translation="MSNKNKDNITLSNQIKRTTQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIIMNKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQKEKILFTEKRIIELGNENDEKELCEISNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDSSINPEGTDEWGATPTRENFTGGDLQGV
                     IEHLDYLSDLGISGLYFCPITIGKTNHRYDTIDYMEIDPALGDKRTLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKDWFYIKDMNKIDIPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIEYLLDVGKYWIHEFDIDAWRLDVSNEVDHAFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVNEVIFNLLGSHDTTRILTYANGNVDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNRDIFNFMKKIIRLRKENKELRSISNEWVLADKE
                     NGAIILKKESIFIIINNSSKDIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
BASE COUNT         8456 a         2546 c         3780 g         7190 t
ORIGIN      
        1 attggaagat ttatgttata ttgagataaa tttattatga tacaaaaaat aatgttagga
       61 taaatttaaa tctttttcta aaaatgtata agtgtaattc ttaaagaaag gatttttaac
      121 aatggatata aaagagttag ttaaaataca aagaaaatat tgtaatacag gtaaaacaag
      181 agatatatcg tttcgtatag aacagttgaa gaaacttaag tcagttgtat cacaaaatga
      241 agaaaaaata cttttagcgc taaagagaga tttagataaa tcggattttg aaggttttat
      301 gacagaggtg ggcatgtttt atagtgaatt aaattttgct ataaagaata taagaaaatg
      361 gagcaaaata aaaagagtta aatcaagtat ggttaatttt ccatctatat ctaaagttgt
      421 tccacaacct tatggtgtta ctctcataat gtcgccttgg aattatccat tccaattagc
      481 acttatacca ttagtttggt cattagcagc aggaaattgt gttatactaa agccttctga
      541 atattctgta tcaacatcta gtatagttaa agatataatt gaaaatgctt tttcaaaaga
      601 atatgttgca gttgttcaag gaagtcaaga agaaagtgaa aaattactat tagaaagatt
      661 tgattatata ttttttacag gaagcactaa tgttggcaaa atagtcatga aatcagcatc
      721 agagcatttg actcctatca ctttagaact tggagggaaa agcccttgta tcattttaaa
      781 agatgccaat atagacctta ctgctaaaag acttacttgg ggaaaactaa taaatgcagg
      841 acaaacttgt gtggctccag attatgtttt agtgcatgaa gataaaaaaa atgagttaat
      901 agagaaaata aaatattata ctaataagta ttttggagat aatccgtctg ctaatgagca
      961 atttcctaaa atcataaatc agagacattt tagtcgtata ttatctctta ttgataagga
     1021 taaggtaatc tatggtggaa attataataa ggagacatta aagatagagc caactatagt
     1081 agacaatgtt aattgggatg ataatataat gaaggaagaa atatttgggc ctatatttcc
     1141 aattttaaca tataaagatt tggatgaagt aatacaaaaa attatacaaa tgccaaatcc
     1201 attagccctt tatattttta caaaaaataa gtacctagaa aataaaattt tagaaatgat
     1261 tccagcgggt ggatgttgta tcaatgacac agttactcat atagctacga attacttacc
     1321 ttttggtggt attggtgaaa gtggtatggg atcatatcat ggaaaagctg gattcgatac
     1381 atttactcat tataagagtg tgttaaaaaa attaaatttg gatgttccta ttagatatgc
     1441 tccatatgat aataaattaa ttaagattct taaaaagata atgtaggtta tattgtagaa
     1501 aaataaatat aaataaaatt gaatatttgt attctgaata tattttattt ttaatttggc
     1561 atatttgtta taaaagtggt gattttatga taaaatttaa ttatatagaa ataaggagga
     1621 aaaaatgaaa attaattgga atacaaaata cacaacaata gcaatttata cctttataat
     1681 agcggctagt agtattatat tttatctagt atcatcacaa attgatgtat tttctaataa
     1741 tttagacgct atgtttacaa cattacaacc ttttataata ggatttgcta ttgcatatct
     1801 tcttaatttt attttaaagt tttatgaaga cagaattttt ataaaaagtg agaaattgaa
     1861 aaaactaaaa caaagttcaa aaagaggttt gggtatttta ttaacatatg caacagccat
     1921 gttgatactt tacttattta tgtatttcgt attgccacaa gtaattgaga gtattgttgg
     1981 actagcaaat gatataccta tgtatgtaaa caatgcaact aagcttattg ataaattaat
     2041 gactgattta aatcttgatg agcaatactt taatttggca gttgataaat ggaatgagtt
     2101 tgttacatat attataaagt ttgtaacaga tttaatccca atattaggaa gtatgttaaa
     2161 gaatgtagcc tctagtatat ggaatattgt attaggatta attgtttcag tatacctatt
     2221 aattgataaa gaaaaattct atggattaag taaaaaaata acttatgcag tgtttacaga
     2281 aaaacaagct gctagaattt tagaattaac tcacagaagt aactatacat ttggaagatt
     2341 cttaggtggg aaaatattag attcattcat tgtaggtatt ctaacatttg taatacttac
     2401 attagttaaa atgccatata cattactaat atcagttata attggtatta caaatattat
     2461 tcctttcttt ggacctttat ttggagcaat accatctaca ctaatagtat tgtttgtatc
     2521 tcctataaaa gctttctggt tattgttaat tatattaata attcaacaga tagatggaaa
     2581 tattataggg cctaaaatac ttggagattc aattgggata tctgcatttt ggattttgtt
     2641 ctccttattg gttgcaggaa aattattagg ttttattgga atggttatag gagttccaat
     2701 gtttgcagta atttattcta taattaagga tattgttgaa ggtaaattag acaaaaaggg
     2761 attaccgaca gatacttccg attatatgta actaaaaaat gttatgtata attaaaaata
     2821 tataaattaa gtaatattta aagcactgag aaagtcaaac tcttggtgct ttttagatat
     2881 aaaattatta tagaagaggt gttttttgtg gcatttatag aatgtaaatt taaatctaag
     2941 tatactggag gagaaactga tataattgta attttacctg tagcaaatgg aaaagaactt
     3001 tttagtggta aagagatata tgattttgaa ggtaaattta aaacattata cttatttcat
     3061 ggtttagaag atgaccaaac ctcatggatt agatatacta atgtagagca ttatgctaaa
     3121 aataaaaata tagctctagt gataccaaga gtagaaacta gtttttacac agatatggta
     3181 tatggacacc aatattttac ttttgtaagt gaggaattac ctaaatttgt tagagctata
     3241 tttcctttat cagataaaag ggaggacaac tttgtagctg gcatgtctat gggaggatat
     3301 ggagctttaa agttagcact ttcaaaacca aaagagtttt cggcagttgc aagtttttct
     3361 ggttcacctg atatgattca tgagttagaa aatcaacaaa tagaaaccaa tgcagatatt
     3421 ctatttcatg attttggtag accagaagat gctagaaata gtgagaatga tttactttac
     3481 atacttaaga accttaaaga gagaaatgaa gacattccta aaatttatca attttgtgga
     3541 gatagagatt ttttatataa aaataatcag atgtttaaaa aatatgcaga gtctttacat
     3601 gtagatgttg aatatgaaga gtgtgtagga gggcatgaat ggcgtctttg gaatttatgg
     3661 ataaagaaat ttatagatat aattgggtag tatgcttatg gtattaacag agatactata
     3721 aaatatcttt aaatatgata aagactgaaa tcataaaatc aaatcatgat tttaaaattt
     3781 cagtctctaa gaatttaata aaattttatt aagttcttac acgagttatt attggagtaa
     3841 aattgtcaac tatatctata tagtatttac tcaattcttc taaaatctct tcgcataaat
     3901 cagtactatg accaagatta ataagaaact gttttgtaaa atgctttatt acagcttgag
     3961 aagatatatc atacttgtgt gaagtataaa ctctaattat ttcaggtttc atagcaagta
     4021 taccaataca agaaagtatt aactcatcat gttctataga ttctttatca ttaacatatc
     4081 ttttcatgac catttcggtt acacttcttt gatagcttaa aatggcttct tcataagcta
     4141 tatccaaata aaaatttcta tatgcttcat tttttagaag gaaacaaagg tcagcattca
     4201 tagcaagaaa gaacatcatc atagtacctt cttcatggta gttatagatt aaagattgca
     4261 tttcatttct tatatcttca tatattatag ctcctatttc gcttttactt gaaaagtaat
     4321 agcttattag acctaaattt atattagctc tttctgcaat ttgcctagtc gttgtcttat
     4381 gataaccttg ctcaaaaaat aattctctag cagcacttat aatactagct tttgtttctt
     4441 tgcctttttc tgattttgac atatttactg tgtatacctc tcttttcaat ctttttttga
     4501 aaatttgcta actataaata ttgtaataga accacctatt ataggaacca aaattctatc
     4561 aaatacagta agaataccaa tcatatttaa taatgccagt ataacactta ctataacagc
     4621 atatatagct cctttttttg tagcatcttt ccagcaaaga ccaattacaa atggtgcaaa
     4681 tattacacct gtacatagtg gagctggcca aaacaataat tctaataaac tatcaaattt
     4741 aagtgctatg attgcaccta ttatagctgt tagagctgat gcaatttgag aatactttag
     4801 agtatttttt aaatcattaa attctatatt agggtgtaac aatttgttat aaatatctct
     4861 tgatatgata gcactcattg aggtcattaa tgaatcggca gtagacatta tggcagccaa
     4921 tatagcagat aagaacaata cagagattaa aggtggcaaa gtagtcgata tcatttgagg
     4981 taaaacctga acagatgata tgtttggaaa taaactacca ccaatagctc caattattcc
     5041 tatagggaaa gcaagaaata atagtataaa tcctgcaatt acactacttt taactgcatt
     5101 tttagcatta tcagcacatt gatatcttaa aaaactttca taagaaaata ttgagcctaa
     5161 aactaatggt aaaactgtat acataaaatc actaatcgat ttatttcctg gaaagaatgg
     5221 ttcttttacc attgattgta acataagtaa agggttgtcg ccaactaatt ttaagcttat
     5281 ataagctact attggcaaaa acactataca aatagcaagt tgaataaatg ctgatactgc
     5341 aactccccac attcctgatg tataagtata tataatgatg actataactc ctataattac
     5401 agctatatca taaggaatgc caaatgcagt agacacagaa ccaaaagaga ttaattgact
     5461 acccataatg gctagtatag atattggtgt tacaagactt tgataagctc ttaaaaatat
     5521 actatgacca tatctagttt caatataatc agcaggtgtt atatcgcaag ataagcttct
     5581 taattttcct gcaaaaaatg cgtttataaa gcaggctaaa gctgcaccta tagtagaata
     5641 cattccaacc caaagccctc tttcagctcc ccattgaact ccaccaacta agcaccctcc
     5701 tccaaaagat gtagcagcaa tggttgcagc tagtataggt aaaggaagat ttctacctgc
     5761 aattaggaaa tcggatgctg ttttaacttt ttttgaaaaa taaaaaccaa tccatatgta
     5821 tattgcacac gtaacaatta aaagtaacat agtctcttct cctttataaa atattttaat
     5881 aaaatatatt ttaaatatat tttatataaa agtagtacga tatttgtttt attggcttta
     5941 gattaatata gctataataa tttatgatat tagatagaaa ttacataaaa atagaaaatt
     6001 gaaaattctg aaatttttgc atattgatat ttatcgcgta gattcttttt ttgtaattgt
     6061 aacatgcttt tatttttaaa tcaatagtac atgtataaaa ataaaaggaa tttaaataag
     6121 aaaaagatat ttttaatatc tggatgtagt ataaaaatat cttgaataaa ttactcttga
     6181 ataaaattga aaaaattaaa atcaactaga aatacgataa aataatttaa aatatgtatt
     6241 ttgatgacat ttaaaaacaa taaaataata aaaaacaaat ctaaattaag cttaaatggc
     6301 tttttagtta attttaatag taaaaattaa acttaaaaaa tatttgacaa ttatgaattt
     6361 tgagaatata attgaattaa aattagacac atataaaaat atactctgaa tcaagaagga
     6421 tatatttaag attcaaaata tatattatta tacgtgaata ataaaaaagt aagcaaattt
     6481 tataagggag gggtagatgt gagtagtcaa gaaagcaaac caaaaggaaa ctttatatca
     6541 aattttagag atgatatgag agaccctaag aaaagagcaa tatacacata ttcaagttct
     6601 ataaacctag cgtacaattt tataggttac tttgtatcaa ctgttacaaa tatcttttta
     6661 accgatgtgg caaaacttgg tgtaattatg gcaggtggta tgcaaatcat acaatctttc
     6721 ataaaaattg ctatagctcc tataacaggt acagtatttg acaaacaacc attcaaaaaa
     6781 ggaaaatatt atccatggct tagatatgca ccagcagcac tagcattaac gtatggaata
     6841 tttttcatag ttccattaat gaaaataagt ccagcattac ttttaccttt gatgacagct
     6901 ttattattaa tagcatcttg tgctcagcaa gtagttttca ctataattta tgctatttac
     6961 cctgtagttg ctaagacacc tagagacaga gttataggtt caactactac gaatatattc
     7021 aaagaagttg gtaaattctt agtaggtttt tcatatccgt tattattagt tttatttgca
     7081 gatgtattag gtggagaggg aatgggttat ttaggtacct atttattctt tgcagcagga
     7141 tgtcttttag tattttggtt ttcttcaaca gagataataa aatctggagc agaagaagaa
     7201 gttcttcaaa aagaagagaa gccaaagatt aaagcaagtg aaatggcaaa agctttattc
     7261 actaatgtac cacttatgat ggcattttgt ctagaatttc ttatatgtat aagatctata
     7321 ggattaggac ctttggctcc atattatttt aaatatgtaa taggggatga acgtggatta
     7381 gcagtatttt tatcaatcat gcctttggta agtgtagcgt tcatgttttt tgcaccagta
     7441 ttcataaaaa tctgtagaga gcaaaaacta gcttcgataa tttctttttc tatatgtgca
     7501 ttatgccact tattggttgc atggactcct tgggggaaaa ctactttagg agtaactatg
     7561 ttgctggcaa ttggtggagg tttttcaaat gtagtatcaa taataaatct taattttttt
     7621 gcaggttctt gtgattatgg tcactggaaa tcaggaaaag acttacctgg tttaagtatg
     7681 tcattatatc cagttgcaat acaagtagga gtattacttg caactactat aagaacagtt
     7741 ttaatgaact caatgggata tcaagctgat atggtagtca cagaagcagt taaatcaggt
     7801 tttataaata tgatttctta ttctatggca atacctttaa taatagctgt tgttatagca
     7861 atactatatc cagtaagtga caagaaatta aatcaaataa gagaagaact aaatcaaaga
     7921 aatgcttagt taaaagaaag ttaagtagat gactaattta agttattaaa gtaagtagac
     7981 gcaatagcgt ttatataaat gaaaatacat atacagaggg ggcttttaaa aatgatagaa
     8041 aaattattga gaaatacagt aaaagaatta catcaatatg ttccaggtga gccaatagaa
     8101 aaagttaagg aaaagtatgg tgtaaaagaa ataataaaat tagcttcaaa tgaaaatcct
     8161 ctaggtccat caccaaaagc aatggaagct atgattgaaa tgttaaaaca aggtcaactt
     8221 tatccagaac cagaagctaa cgaacttaga agaaaattag ctgaaaagct agacttaaaa
     8281 ccagaaaatt ttattgttgc taatggtgct gataacgtta tcacactaat aggtgaggct
     8341 tttataaata gaggagatga agttatatat tgtaacccaa catttccatc atatagaact
     8401 gcaactataa aaaatgaagg gataccagta gaagtacctc taacagaaga ttataagtat
     8461 gatttacaag gtatattgga taaaattaca gataaaacaa aattaatatg tgtatgcaac
     8521 cctaataatc caacaggaac aattgtagat gataaagagt tagaagaatt tttaaagaaa
     8581 gttcctgaaa atattataac tatattggat gaagcatata tagaattttt aacagttcct
     8641 aattatgtgg atggacttaa gtatgtaagg gaaaattaca atgttatagt aacaagaact
     8701 ttctctaaaa tatatggtct tgcagggctt agagtaggat atggtattgc taaagatgag
     8761 ataataagaa ctctatttac agtaaaagag cctttctctg caaaccgtgt tgctataagt
     8821 ggagcaacag cagcacttga tgatgaagag tttataaaag aaacctatga attaaataga
     8881 gttggtatgg cttactttaa agaagagttt acaaaaatgg gatttgatgt tgtagattca
     8941 caatcaaatt tcctttatgt agatatgaaa acagatatac ctaagttatt tgaagacttg
     9001 aaaaaaagag ggtttgtaat aagaccaagt gctacacatg cacgtgtaag tattggaact
     9061 atggaagaaa ataagaaatt tgtagcagtt ttaaaggaaa tattaaatat taaagaggag
     9121 ccaagtattg gataatagat agaaatatta tgaaacgggg tgtagatatg aacttaaaaa
     9181 taaacgcaga gagatgtaaa agttgtgaat actgcgttat atcttgtaaa aaaggagcat
     9241 taaaaatatc aagtaagata aataaagaag gttatgctca tgtagaagtt gatgagagta
     9301 aatgcatact ttgtggaatt tgctatcaag tgtgtccaga taatgttttt gaaataatta
     9361 aagaagaagc atgtcaagag gcttagaagg agttgggata atatgaaaaa aatgtggaag
     9421 gggaaccacg ccattgcaga agcagcccta agaggtggtt gtgaatttta tgcaggatat
     9481 ccaattacac cgcaaacaga ggtaatggaa tttttatcac atagaatgtc tgaacttgga
     9541 agaactttta tacaatctga aaatgagatg gctgctatat atatggtata tggagcatat
     9601 gcaagtggaa tgaggtctat gacgagttct tcaggaccag gaatatcttt aaaacaagaa
     9661 gggatttctt acttatgtgc aaatcattac ccttgtgtaa tcgtaaatgt acagagatgg
     9721 ggacctggtc ttggttcatt ggattcagca cagacagact acctaagaga tactagaggg
     9781 ggaggaaatg gagattatca tttgatagtt tatgcaccaa acagtattca agagactgta
     9841 gatttgatgt ataactcatt tgatgtagcg gaaaaataca gagtacctgt tgaaattttg
     9901 acggaagcag ctttaggtca aatgatggaa ccagtagaat ttccagagtt taagaagaga
     9961 gaagaagatt taggttggac ttacgatgga agtaatagag accatgcaaa ggttgcagat
    10021 aaccaaaagc caactttttg tatggagaaa cgtatgagaa taagtgaaaa tgaacaacaa
    10081 tgggaagatt atcaaataga agatgcagaa tatgtgtttg tagcgttcgg tataccatca
    10141 agaacaacta tgaatgctgt tagaagactt agagaacaag gtgaaaaagt tggaataata
    10201 agaccaataa cagtttggcc tttcccatat aaagcatttg aaaaggtaag caaagatgta
    10261 aaaggattta tatcagtaga atcaacagac acaggtcaat tagtagaaga tgttgcttta
    10321 gcatcaaaga aagtatgcaa agaaaatgta cctgtgtatg gtctatttag tggaaatcat
    10381 ataccaaaaa cattgcaagt aatggacact tatagcaaaa taaaatctgg cgaaatcaag
    10441 gaggtgttct aatatggcta cagaaaaatt aacacctagc gttgtttcaa taccaaacaa
    10501 gttttgccca ggttgtggtc atggaatagt aaaccgtata atagcagagg taatagaaga
    10561 gcatggatat gaaaaaaatc atgtgttgac attaggagtt ggttgtgttt gtaatatgaa
    10621 ttttagctgg aatggtgata agatgcaaac tgcacatggt agagcttcat ctacagctat
    10681 aggagttaaa gtagcacttc cagatacact agtgatgact tatcaaggag atggagatgc
    10741 ttatgtcata ggtctttctg aaactttaaa tacagcatat agaaatcata atgtgactgt
    10801 atttgtaata aataataata attttgcaat gactggtgga caaatgtcat ggaccactat
    10861 gccaggtcaa gttacaacaa caagtgcaaa tggaagagat ataagtacta ctggtagtcc
    10921 actaaaagtt cctgagatgg tggcaaactt ctttgatgta gcgtatgtag caagaggctc
    10981 agttcatagc ccaaaagaaa taattaatct aaaaaaatat ataaaaaatg caatagaagc
    11041 tcaattaaat ggagagggat attccttagt tgaaatatta gcgccttgtc caactaactg
    11101 gagtgtatca ctagagaaat ctatcaaatg gatggaagaa gaaatagtgc catattatac
    11161 tcttggcgaa tttaagcaaa gggatggtga atagttatgg aaaaagagtt agtatttgca
    11221 gggtttggtg gtcaaggagt tttaactctt ggtttgattg tagctgagtc agcacttgaa
    11281 ttgggtaaac aagtaacttg gatgcctgca tatggtccaa ctatgagagg tggaaaagcc
    11341 tatagtgtag taaagttttc tgatgagagt ataggtggac ctgatatgga agaaatagat
    11401 gttttagtag caatgaataa accatcttta gattatataa atttagtcaa ggaaggtgga
    11461 acagtagtta ttaatacatc tgcaatagat gagaatatag cattaagaga agatataagt
    11521 gtagttaaaa taaattgtca agaattagct caaaaagtaa ataatccaaa agcagcaaat
    11581 atagtagtac ttggagcatt aattgctaag actggattgt ttgaaaaaga attagcttta
    11641 aaaactatgt gtgatttctt tgaggaaaaa ggaaaaggaa agtttaatat tcaaaatgaa
    11701 gcagcattca tggaaggcta taataacgcc atttgataaa ttacccttat cttaagtgat
    11761 ttatctcgag atttaataat ctttagtgcc aagagaaatt tcatcttgag ataaaattca
    11821 cttaaaatca caactataaa catataggag cgtgaattta tgagtttgga aaaacttatc
    11881 agaccaaaaa gtattgctat agtaggagtg actgataaac ttggttttgg gagaagtgca
    11941 gcacttagta tagtaaaaag taaggacaca gatagagtat attatgttaa tcctaaaaga
    12001 gaagaattgt ttgggagaaa atgttataaa acgatacaag aagttccaga gatagtagac
    12061 tgtgtagtag tatgtacacc tagaaatgta gttccatctg tattaaaaga ttctgcagag
    12121 ttaggaacaa aggcagcagt agtatatgcc agtggatttg cagaggaagg tacagaggaa
    12181 ggtacagatt tagaaaatca acttatagaa atatcaaata catacgatat gaaaatattg
    12241 ggtccaaact gcatgggatt gctaaattgt atagataaag ttaatttgtg ggcaggaggt
    12301 tctaaatggg atttagatac taaaaagcct ggtataggaa ttgtagggca gagtggattt
    12361 ataactgctg agattgtttc aagtgattat tttaatatat cttatggttt ttcaacagga
    12421 aatggaaaca tagttacact agaagatgca gtagatttcc ttgtagatga taattatgca
    12481 tcagtaatag caatctacct tgaaggttta aaaaatcctc aaaaatttat agatgcttta
    12541 aaaagagcag cacaaaaaag aaagccagtg ataatcttga aatcaggaag gtcagaaaaa
    12601 ggagctattt ctgctgcttc tcatacagga aatttagctg gttcaagtaa ggcttttgaa
    12661 agtatttttg aaaaatatgg agtaatttct gtagaaaatt tagaacaatt tatgtgctta
    12721 gcacaagctt ttagtgttct agatggcaat ttacctacaa attctaattt tgcagcaata
    12781 aacttctcag gaggagaaaa tacgatttgt gcggatttag cagaagaaaa tggtgtagaa
    12841 cttgcagaga tatcttctga aactaaagaa gaaatgaaaa aatatcttcc gggatttgca
    12901 acacctaaaa atccactaga tgctacaaca gcattattcc acgaaaagga tatgatagta
    12961 ggtctattac atacctttga aaaggacagt agtgttggat ttactatggt aggtgcaaat
    13021 atacgagatg aagaaaatga aatgcacgaa acactatgtc aagctgtaag tgaagctaga
    13081 gaacaaggat tgaaaaagcc tgtgtttgca gttcctacac ttgaaggaaa tagatattta
    13141 gattatagga atagattaga atacaatcaa gtgcctataa tgtcatcagt tggaactaca
    13201 tttacttgtt ttaataaaat ggctaagttt atagattatg attattcaaa aaggacttta
    13261 gaatttaaag ctgttaagaa aagagagtca aataatgtag tagcattatc agaattagat
    13321 agtaagattg agatgaagaa atatggagta ccagttccag gacaaggtaa tgcaaaaagt
    13381 attgatgaat tagatgaaat cttaaaatat attaaatatc ctgttgtttt aaaaataaat
    13441 tcttccgaaa tcttgcacaa atctgatgtt ggaggagtca aaataggaat taagaataga
    13501 gatgaggcag tagatgcata taatgagatt ttaactaatg taaaaaaagc aaaaccggat
    13561 gctaatattg atggtatatt agttcaagaa atggtagaaa gtggtataga aattattatt
    13621 ggtataacta atgatgacca atttggacca atgttgctag ttgggttagg aggagtcttt
    13681 gtagaagtat ttaaagatac tacattatat ccattaccta taaatcacga tgaagctatt
    13741 atgatgctta aaaaactaaa atcatttaag cttttaaatg gttatagagg aagtgagcct
    13801 tgcgatattg atgctcttgc agatatgatg gtcaaattag gaaaatatgc ttacgaaaat
    13861 aaggatgaag tcaaggaaat agacttaaat ccagtgtttg tatatcctaa aggaaaaggc
    13921 gtatgtgcag tagatgcctt aatagttaaa tataaatagt ttataagttt tggtacttaa
    13981 ccataattaa agcactgact gaaaatcaca ttttgtaagt taaatagtgt gattttcggt
    14041 caccccaaat ttactttaaa aaaattttaa agtaaaagta tagttttaag tttcattgtg
    14101 aaatagtact gtaaaaacaa taaaatacta catataaaac gaataataaa aggtgtttta
    14161 atgataagaa tcaattttga ctttcactaa aacaccttct ttattatatg aaaaattttt
    14221 aaatgttata ttgtcacagg tgggtttgtt ggagctgaat atgtacgatt agcaaattct
    14281 tggtcaacaa agaatagacc accttctcca gcaagtttaa cacgttttat attgtcttca
    14341 caatttgttt cttcttctgc ttgttcagat ataaaccaaa gtaagaattg agaagttcta
    14401 aagtctgact cagagtttgc tacagctgct aaattgttta ttaaagctgt aacctttttt
    14461 tcatgagcta acgtacgctc aagaatatcc attgcagaag taaagtctga atctggcatt
    14521 gggatagcat caagctgaac ctttcctcct acattgtgta agtatttgta aaaaaacata
    14581 gcgtggtctg tctcttcttt atattgaaca taaaaccaat tagaaaatcc tttaagtcct
    14641 tctgcttcaa ggtaagaaga catagaaaga taaagatatg cagaatataa ttcatggtta
    14701 atctgctcat taagtaattt ttccatttta gctgaaatca tttttatacc tccaaatttt
    14761 aaatgctctt ataaaatata ataatattaa atggaaaaat attcaataaa agtgtttaaa
    14821 tattttacat atttaataaa aatttatact accattaaaa aagttataac ttacaatggc
    14881 tatagagccg attaatggtg catttgctcc aaaatttgaa tgtcttacac ttattttttt
    14941 atatttagaa aaacttgctg aaacagtcaa tttttttaat aatgtatttt ctataaatgt
    15001 accaggaata ttaaagtcat agcctattat tatagaacta caatcaatca acgtaagtgt
    15061 attaaccaat gcatatgata cgtatgtaca aaattcatca agcaaaaaca tagcgagact
    15121 atctttatta tttgcctcat ctattaattt gactaaagaa aaatctttac agttaattaa
    15181 cggggaatta ggataaatat ggctcaatga ttcaattctt ttaattagat tactgacact
    15241 tgtataataa tctaaacatc cattgttacc acaactgcac aatggtccac taaaattaat
    15301 tgatgtatgt cctatctctc cactttgccc tagattgcca gtatgaagtt tattttctag
    15361 aactagacca gctccaatac cattcattat gtgtaggtat atataatttg atatattttt
    15421 acctaagcca tacatttttt ctgccaatgc gcccgaatta gcatcgttta ttaaaaatat
    15481 tggcaaatca gacagttctt ttataaaagc tactatattt aggtttgata catttccaaa
    15541 gtctggggga tttagtatgg taccatttat atcatctact ggacctattg aagaaatacc
    15601 aattccaatt atatctctct tgttgatttt cattattttg gtaaacattc tttttattat
    15661 atcttttaag acatcatttg atagacattt agggtaagtt tcagaaagtt gttttacaat
    15721 attacctttt aaatctgaaa taattacctt acatatattt cttcttatta ggattccaca
    15781 aatacaaggt gatatattag aaatatctaa taaaataggt ttacgacctg atgaatgtgc
    15841 atttaaagtt gatgactcta tttccttaat catgttttca ttaataagtt cagttactag
    15901 atttgataaa gtcattttag taagtcctgt agacttagct aaatcaaccc tggacatagg
    15961 tgtatttgta gaaagtaatt tcaatattat taacttattt ttaattttta catcttttat
    16021 gttagaacct tgtttgttac tcatcttaaa tctccttaaa taaagttaag tgttttattt
    16081 attttcaagt atgctatcac cttataatag agcaacattt ttttacttga aaatatcatt
    16141 aattagaata tatcacatta tatatcataa aacacaaaaa aatgttaggc ttaaattaaa
    16201 aattaaaagt taaaagttaa aagtagattg agatataaat agtagatact caattaaaaa
    16261 agataatgat aacaatatct gcttttataa agaaaccacc atttcaagca ttactttaag
    16321 tagttaagtt gatggtagtt catatataat aacttgataa aaggtttact taataataaa
    16381 tagattatgc aaatctacaa tctatttatt gtatacaata aaatttcatt ttgtaaaaca
    16441 gtgaattaaa tatgaaatac agagatagat ttttattaca aattgttacc aaatatagat
    16501 atattagaac agaaatctag taaattgtaa ctaaaatgta aatttttcct ttaatctata
    16561 caatattatg gaaacttttt gtaatctatg atataataac aaatatataa ttattaaatt
    16621 ataataaatg actatagcgt agatgtatta ctatgctata gtcatttttg aattaaactt
    16681 gatatatcaa gggggaagaa tatgagaaca attagaagag ttttagcatt aggcttaaca
    16741 ttagctatat ttctaataaa tgtacctaat gtagatgcat taacatcaga tacaattaaa
    16801 ggtaataata tatatgagac ggctggatca atagcagata aaaagagtta tgatacagca
    16861 attatggtaa atatggataa ttctatagca gatggtcttt cagcaagtgg tcttgcaggt
    16921 gctgttgatg ctccaatttt gcttgcacaa aaaaataaga tacctagtga aacaaaacaa
    16981 agactaaaaa atgttaaaaa aatatacata ataggtaaag aattatcaat aagtaaatca
    17041 gtagaaaacg aactgaaaaa tacaggagca caggtaacta gattgggtgg agatgacaga
    17101 ataaagacta gttatagtgt tgctaaagag gtaaatggta tcaaaaaagt tgatgaagtg
    17161 atactaacta atgcatataa aggagaagca gatacaataa gtgctgcacc tgtatcagta
    17221 agagatatag ctcctatagt acttacagat ggaaagagtg tacctttttc aacaagtaat
    17281 gtaaaaacat atgcagtagg tggaagtata tccatgagca ctagtttagt taataaaact
    17341 aatgctaaaa gacttggcgg ttcagataga tatgatacaa ataagaaagt tataaaagag
    17401 ttttatccag atgcatcaga attttattta agtgatggat atgatttagt aaatgcactt
    17461 acaggttcaa caattgctaa ggaaaatcca attgtattgg tgtcagaaag tagtgataag
    17521 tctatattag caggagcaga taagattact agattaggtt caataagtga tagtgtgtat
    17581 aataagtgcg tttctgttgc acaaaataat ggagattcgt ctacaaaagg tgattcacct
    17641 atgaaaaatg agacaagcat attaggtcag ccaacagcta gtttagaagc ttgtttaaaa
    17701 tgggccaaat ctaaaaaagc taatgattta tttatagagt taataccaat attatatgat
    17761 actgctgttc aggaaggtgt aaatcctgtt ttggcagtag ctcaatctgc aaaagaaact
    17821 ggtttttgta attttggtgg agtgttagat gcatcattta agaatccttg tggacttaaa
    17881 acttctgtag gaggttctga tactgataag aatgctcatt caagatttga tacttgggaa
    17941 gaaggaatat tagctcaaat tcaacattta tgcttatatg caggacaaga tggttatcca
    18001 ctttcaaatc cagtagaccc tagacatgaa aagtctttat ttggtaaagc taagacagtt
    18061 gaaagtctat ctaataattg ggctggaggt caatatggac aagatttagt aagaatgatg
    18121 ggagaaattg aggcaacaaa ataattgaag attatcaaat atccaataaa taaggattga
    18181 ttattatgaa aaagagtaat atttttagta ttatatttcc tacagtcata atggtgctaa
    18241 tgtttttaac ttttgttaca gatatattta atcttgcaga tgttcaatct aaaagtattt
    18301 ttgttgtagg aatggttttg atttttccaa tttctttttt aatacaagga ataatttgtg
    18361 tattaaataa gactagttgg attttatctc ttattgtgtc tttattaact tatatagtat
    18421 taatgtatat atttttaaat gattctgcat atatatatgt tttactttat acagcttttt
    18481 atatgattgg acatatagca gccaagttct attacaaaat taagactttt aaaaattaaa
    18541 tttaagtata taaaattaat attaagggaa gtatctttaa tgattttcta aaatcaaaaa
    18601 taggtgcttc tctttttgta aaaataaaga tatgtaaata aaatttaacc attataattt
    18661 tcttttaaca aatgtataca ataaacttgt tgtataatta agatagataa aataaaggga
    18721 gggataatat gaatttaata gataatcata ttcatactaa tttttcaagt gatggaaagg
    18781 attcaatgga agatacaata aaaaaagcta taagtattgg tgttagatat ttaactttta
    18841 cagaccattt agaacatgac gaagatagag gattttgcat aaattataat gactatgttc
    18901 cagtgtttaa caagtttaaa gaaaaatata aaaaagacat agagttatta ttaggtgttg
    18961 aagtaggtta tagaaaacat ctaaaaaatg aaatagaaga aataataaat tctaatcctt
    19021 ttgattttgt attgtgctca actcatacaa ttgacaatat acctgttcca tcaaaggcat
    19081 attttaaagg acttagcaaa gaagatgcgt attataaata ttttaatagc atacttgaaa
    19141 ctaatcgtga atttagagat tataatatat atggtcattt agattatata tctaggtatg
    19201 gaatatattc agataataga gttatataca atgactttaa agatattatt gatgaggttt
    19261 taaaatcaat aatcaataat ggtagtggta tagagctaaa tacatctggt tatagatacg
    19321 gactgaatgc tatacatcca aatgaagata ttctaaaaag atataaagaa cttggagggt
    19381 ttatagttac tgtaggttct gattctcata gagtagaaga tatatgcaaa gattttgatg
    19441 tggcctatga tatgcttaag tatcttgact ttaaatatgt atctttattt aaagaaagag
    19501 aaacttattt tataaatata gaaaaagtta aatctaacaa tatagcttag agtttatttt
    19561 gaagtaaatt aatggatagt taaaaagtca atagttataa tattgtatcc tctagaaaaa
    19621 tactagaggt ttttattttg caaaaataac taaatagaat taaatttaaa caatatagtt
    19681 tattttaaat tgaatagttt attgttgata tattttacta ttatatattt ttattgtgat
    19741 ataatagtaa aatatattaa cctatcttta gattatataa attattataa aggagggaaa
    19801 tttcaaaatg tctaataaaa ataaagataa tataacttta agtaatcaaa tcaaaagaac
    19861 aactcaaaat agtttaacaa aagaagctat attacatata ccaatgagta attatgccta
    19921 tggttatgat agagaaacac tacatataag acttagaact aaaaaaaatg aagctaaaag
    19981 agtaatttta cgaataggag accaatatgt ttgggataaa ggtggtgcag gaggaggaaa
    20041 tttaaatgca tctggagttg gttggtctgg tggaacaaat ataataatga acaaagaagt
    20101 agaaactgaa ttatttgatt attggatagc taagtgtaaa cctttaaata agcgttcacg
    20161 atatggcttt ataatagaag gccaaaaaga aaagatttta tttacagaaa aaagaataat
    20221 agaattaggg aatgaaaatg atgaaaaaga attatgtgaa ataagtaatt tttttggata
    20281 tccatattta aattatatag atatacctaa agtgccaaat tgggtgaaag atactgtttg
    20341 gtatcagata tttccagata gatttgcaaa tggagattca tctataaatc cagaaggaac
    20401 agatgaatgg ggagctactc caactagaga aaattttaca ggtggagatt tacaaggtgt
    20461 gatagagcac ttagattatt tgagtgattt ggggataagt ggactttact tttgccctat
    20521 tacaattgga aaaaccaatc atagatacga tacaatagat tatatggaga tagaccctgc
    20581 cttaggggat aaaaggactt taaaaaaact aatagaagaa gcacataaga gaaatataaa
    20641 aataatgttg gatgctgttt ttaatcatat aggatattat tctaaacagt ggcaagatgt
    20701 agttcaaaat aaggaaaatt ctcgatataa agactggttt tatataaaag atatgaataa
    20761 aattgatatt ccaatagaac agatagatga aaaaaatata ccttatgaaa cctttgggtg
    20821 tgaaaaatat atgcctaaac ttaatacaga aaattcagaa gtaatagaat atttattgga
    20881 tgtaggtaag tactggatac atgaatttga tatagatgca tggagattag atgtttcaaa
    20941 tgaagtagac catgcttttt ggagaaagtt cagagaagaa gttaaaaaag taaaaccaga
    21001 catctatata ttgggagaaa tttggcatgg tagtttacca tggctaatgg gtgaccaatt
    21061 tgattcagtt atgaattact tgatgtcaga agccatgaaa aaattctttt gtacagatga
    21121 gataaatgct gaagagttta agtatatgat aaatgatgta atggtaagtt atccaataca
    21181 agttaatgaa gttattttta atttacttgg aagtcatgat actacaagaa tattgactta
    21241 tgctaatgga aatgttgata gatttaaact tgcatatatg tttatgtttg tacaaacggg
    21301 atgtccttgt atatactatg gtgatgaaat tggaatggaa ggagaattaa gttcaatatc
    21361 tgaaggacaa agaaaatgta tggaatggaa tgaagaaaaa tggaatagag atatatttaa
    21421 ttttatgaag aagattatta ggcttcgtaa agaaaataaa gagcttaggt ctatatcaaa
    21481 tgaatgggtg ttagcagata aggaaaatgg agcaattata ttaaaaaaag agtccatttt
    21541 tataataata aataattcat ctaaagatat aattttgaca ttaccagatt atttagcaaa
    21601 taaaaaagta aaagatttat atgaagaaga aatagttgat ttaaaagaag aactaatgtt
    21661 agagaaatac aagttcatta ttttaaaata atacaaaagg gtatttattt tagattttat
    21721 gttaaattat tatacagttt aaacaaatct ttaagaagat aaaaaaatat ggtctataag
    21781 ggaatgaatt agaagtagat tttaaattaa agactagatt agaatagata attttataaa
    21841 taatatctta aatacaagaa agaaaataaa ttgattatta gtctaaaaaa ttcttgtaga
    21901 aagagggaat aagaatgatt gaagcattta tatttgatta aaaaatagct acacacactt
    21961 gtgactttag tc
//
LOCUS       DBGJFK010000065        21752 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.065, whole genome shotgun sequence.
ACCESSION   DBGJFK010000065 DBGJFK010000000
VERSION     DBGJFK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.065"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            229..1389
                     /locus_tag="ACOIAP_002760"
     CDS             229..1389
                     /locus_tag="ACOIAP_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HGZ2639639.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGIYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGTGSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPRFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISRLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLS"
     gene            1729..1890
                     /locus_tag="ACOIAP_002761"
     CDS             1729..1890
                     /locus_tag="ACOIAP_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639640.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2083..2712
                     /locus_tag="ACOIAP_002762"
     CDS             2083..2712
                     /locus_tag="ACOIAP_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGZ2639641.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLNCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTFKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVVLCGDFNEKNVFLSMFNDMA
                     ISLNKSYLSTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2952..4211
                     /locus_tag="ACOIAP_002763"
     CDS             2952..4211
                     /locus_tag="ACOIAP_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HGZ2639642.1"
                     /translation="MGRRATRVSRLGKEKKRNIVIVLVVLIIAMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKSEALRAITDKYTPEDLNLTYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLNYTDSVIGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLAGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4392..5375
                     /locus_tag="ACOIAP_002764"
     CDS             4392..5375
                     /locus_tag="ACOIAP_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HGZ2639643.1"
                     /translation="MTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIKVIKH
                     NNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGIGLDE
                     LILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDFGITK
                     ANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNLEEKM
                     LQSIDRGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKAYIEV
                     EDEKEEEQKQDKVVQVKKDYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5621..6688
                     /locus_tag="ACOIAP_002765"
     CDS             5621..6688
                     /locus_tag="ACOIAP_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HGZ2639644.1"
                     /translation="MSNIKIIASNKCWIEDIAKKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGILKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYAKDGLEVESEKAIDYIKNHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTKISLYSLSH
                     GAGRKWSRSVCKSRLKSKYNKDTIKQTKFKSQIICSDLNLLFQEAPEAYKNIEQIIES
                     LMEHKLIQVVATMKPLITYKG"
     gene            7202..9112
                     /locus_tag="ACOIAP_002766"
     CDS             7202..9112
                     /locus_tag="ACOIAP_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGZ2639645.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLNPSGNIGVVR
                     RKLAENKEARKIIENSNHVPLEGLFNAGSTIDKIEKGMVIEPIELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKNIEDEINYCIKSNKVDSNASKELKKVRRNIEIT
                     EAKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVDGTILDTSSKGNT
                     VFIEPISVSNLSTELIMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMNLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNVEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPIDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDTLFTNFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9175..9798)
                     /gene="ytaF"
                     /locus_tag="ACOIAP_002767"
     CDS             complement(9175..9798)
                     /gene="ytaF"
                     /locus_tag="ACOIAP_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HGZ2639646.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFFLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLFGCLLGNMFVKNINLNLSWLSGLILLVIGFIKIC"
     gene            9986..10630
                     /locus_tag="ACOIAP_002768"
     CDS             9986..10630
                     /locus_tag="ACOIAP_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639647.1"
                     /translation="MEQHSKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFKNNNNQIFNTDSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            10835..11893
                     /locus_tag="ACOIAP_002769"
     CDS             10835..11893
                     /locus_tag="ACOIAP_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HGZ2639648.1"
                     /translation="MNCKWISKIDERKKCDREADSSGYCIFHKENKSDEEIQLMVDTL
                     NKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FKDKVLFNGCVFLENCDFNRTIFSKDYINDRIFEKVKFKGSDLIVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIVIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFRMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            11997..13181
                     /locus_tag="ACOIAP_002770"
     CDS             11997..13181
                     /locus_tag="ACOIAP_002770"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGZ2639649.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDNYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTSSGDLLGSVDIVSNNSIDNVPLKTKLKMKF
                     AN"
     gene            13388..14101
                     /gene="rpsB"
                     /locus_tag="ACOIAP_002771"
     CDS             13388..14101
                     /gene="rpsB"
                     /locus_tag="ACOIAP_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGZ2639650.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            14180..15091
                     /gene="tsf"
                     /locus_tag="ACOIAP_002772"
     CDS             14180..15091
                     /gene="tsf"
                     /locus_tag="ACOIAP_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGZ2639651.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            15175..15879
                     /gene="pyrH"
                     /locus_tag="ACOIAP_002773"
     CDS             15175..15879
                     /gene="pyrH"
                     /locus_tag="ACOIAP_002773"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGZ2639652.1"
                     /translation="MDKPMYKRVLLKLSGEALAGEKGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            15905..16462
                     /gene="frr"
                     /locus_tag="ACOIAP_002774"
     CDS             15905..16462
                     /gene="frr"
                     /locus_tag="ACOIAP_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGZ2639653.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEDFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            16465..16668
                     /locus_tag="ACOIAP_002775"
     CDS             16465..16668
                     /locus_tag="ACOIAP_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639654.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQDINYTIKSIEGKKDKDKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            16697..17431
                     /locus_tag="ACOIAP_002776"
     CDS             16697..17431
                     /locus_tag="ACOIAP_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGZ2639655.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            17444..18223
                     /locus_tag="ACOIAP_002777"
     CDS             17444..18223
                     /locus_tag="ACOIAP_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGZ2639656.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVNPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINEFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
     gene            18752..18895
                     /locus_tag="ACOIAP_002778"
     CDS             18752..18895
                     /locus_tag="ACOIAP_002778"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2639657.1"
                     /translation="MYNFKYVKDSMGYVFGDKILIDLAECLKRYFRETDTVGRVGGDE
                     FII"
     gene            18985..19083
                     /locus_tag="ACOIAP_002779"
     CDS             18985..19083
                     /locus_tag="ACOIAP_002779"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:NF013180.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2639658.1"
                     /translation="MSVSIGISLYSKYGEQFYKLYRHADSALYRVK"
     gene            19281..21101
                     /locus_tag="ACOIAP_002780"
     CDS             19281..21101
                     /locus_tag="ACOIAP_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2639659.1"
                     /translation="MKKKYDFLIYAAIWLVAIIIFIFSLYHSIEHIKIINYTGIISSE
                     TQKVTKQELNNKRNDKLISQLDSILIELRTGNGKHRLQRCDNKEFQEKLIEMDAMWDS
                     MKKEIRKVRNGGSGDKLYKLSEKYSSLSNQVVFISEKHSDIKLHFFATVLFIYLIIST
                     ISLLIWEYYNKRKFDKIFYTDNLTKIKNQVAFENRAIEILSHAYNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLVIVANVLAKTFNTKETCARVGSDNFVILAKYRESLLYEISKT
                     LTDAIISELNMNVTQTISFCIGAYLVEIEKSNYKYINSIMDKANIAHKVSKMRGISST
                     VWYNENLLKQLQMENSIYNHMYKALENEEFQMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDQFIPLFEKSGFIIELDFYMLKKACSFIKKTFMKKNKYTYPIAVNFSRVTIY
                     QNDFYQRFLDTVREYEIPFKYIEIEVTESAFNEISEPVISILDKLEKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKEKFNRAKVYSIIKCIIEMSHSIDMSIVCEGIET
                     KKDLEFLKTVKCDLGQGFYFSKPIEEKEFFNKYVMDKQYN"
     gene            complement(21186..>21752)
                     /locus_tag="ACOIAP_002781"
     CDS             complement(21186..>21752)
                     /locus_tag="ACOIAP_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639660.1"
                     /translation="KINQFERSYDIGIFKNEQSIHKFIEKIPFVKKDSSNFNYTNYYM
                     EFEDIPEYYEVNFNNYLYIITKFSFIPDGTEIFFTWDEIHCWDEKVATDKTFINGETL
                     VDSYSFPNNEVKNYIQKRESLYRETKKYYKEKGLKIKRHALGSEDGEYVELVDDSILY
                     LLDVHAVEIWEQSKNIEEFLYKYKKYFE"
BASE COUNT         8888 a         2176 c         3658 g         7030 t
ORIGIN      
        1 tttagtaata aaataattgt tgaaaaagat tttaaattca gattattcat ttctaaagta
       61 attaatatgc aaatctttat taatatgtgt caatagttag gtatatatgt atttaattag
      121 catgatatag ataagagtat ttattttaat tgtctattat ctgaaaaagt ctttacttaa
      181 aaatcataaa aaatcaaatt aattaggaaa agaaagggtg tgtataatgt gattgagact
      241 ggatttgtat attgtagttt cttggttgta ttcgtaggtg taattttctt tatggttgat
      301 aaattgaagt ggaaggtatt tgatgttatt aatccaatgc ttttaatata tttaggttca
      361 gctatacttg gatcatttgg tttatttgca cagaatgaag atgttggaat atatcaaaat
      421 ataataacag tgaacttcct tccattaatg ttagtgttct tgttaattca atgtgattta
      481 agaaaaatac taaagatggg acctaaaatg ttattatcat ttttctgtgc tacatttaca
      541 tttatgcttg ggtttgttat agcattcata atttttaaaa attcaatggg tacaggttca
      601 tggaaaattc ttggggcagc atctggttca tggataggtg gctcatcaaa tatgattgcc
      661 gcagctaatg ctctaggagt tgcagaagaa ggtcttagtt atgcaatact tatgggttct
      721 ataggctata cagtatggat gtctgtttgt ctaatgtctg tgaaatttgg acctagattt
      781 aacaaatgga caaagtgcga tacaagtttt atagatgagg ttacatcaaa acttgaaaaa
      841 gaaaataaag ataatacagc acctacgttt gtagaactta tgattttact ttctgttggg
      901 tttggtgttg cttcttttgc acaaattgta tctaagatac ttccaacttc agggatactt
      961 aatgaaacta tgtgggtagt acttgttgca tctacagtgt caatattatt gggtatgaca
     1021 aaaatatcaa ggcttaaggg gagcacattg gtaggaaatg tgtttatgta tttactcctt
     1081 gcagccacag gtagtaaggc aaatttcttt ggattgtcag aagcacctgt ttacataatg
     1141 tttggattgg tagtagtcct tgtacatgct atttcattta tagggcttgc taaactattt
     1201 aaacttgatt tatttacttg tgaggtagga agtatagcta atatcggagg agtaactaca
     1261 gctcctatga ttgctggggt tcacaatcct gtattaatac cagtaggtgt acttatgggg
     1321 cttctaggaa atattatagg tacttattgt gctcttatgg taactcaaat actacatatg
     1381 ttatcttaat aaaaatataa tataaaatta atcatttaaa taagaaaaaa catttcaatt
     1441 taagcataag cttttattga aatgtttttt atttgacaag ataatttatt tcaagaagat
     1501 attttgacat atttagcgta taatattgta aaatttacta aaaatgagat atatttaatt
     1561 tttatattga atcgaacgtc tgtatgatgt ataataaata tatagaacga atgtttgcag
     1621 aacggatgtt ttttgaattt attttaataa tttatgaata tatatcagaa tgcataaata
     1681 tatttaaata taaagattaa aaagaattta aaggagtgtt gataacttat gataattcca
     1741 tcaagaagaa tacaagatat aacattaaca aatttaaaaa atggtgaagt aactttaatt
     1801 gaattggatg aaatatacaa gaagatggga tttttatttg ttgttagtga aggcaaatta
     1861 aaaaagataa aaaaggagaa tcatcattag aaatgaatga aataataaat attataatag
     1921 tttataaaac ctaacttatg tagaatataa atacttaagt taggtttttt tgtgataaag
     1981 tttataagta ctcaatttta taagataggt aatagtctta agtgaaaagt aaataagttt
     2041 aaattttaat aagtattata ttacataaga ggtgatatta ttatgaaaat agtaacctac
     2101 aatattcata aagggatgga ttcaaataat agattaactc taactaaaat ggggttatat
     2161 ttaaaacaat tgaattgtga tgtaatttgt ttacaagaag tattgtatcc tcagttttta
     2221 gctttaaaag ctgttttaaa tatggatggt gtctttgcca caaatgtaaa aaaagtaaat
     2281 atgatatatg gtatttgtac atttacaaca tttaaaatgt taaacagtaa tcattttttc
     2341 ttaactagca aaaaagaaca acgaggagct ctttgtataa ctatagatgc atatggaaga
     2401 attataaatg taataaatac tcacttggga cttgatagac aggagagagc aaaacaatta
     2461 gacgaaataa tagactatag gaatagatta gtggggatag ttgtcttatg tggtgatttt
     2521 aatgagaaaa atgtcttttt aagtatgttc aatgatatgg ctatttcact aaacaagtct
     2581 tacttgtcaa cctttgaaaa atcaaactct agaatagatt acatttttgt taataaaaat
     2641 actgaactaa aaggatatac agtagaaaaa atttacctgt cagaccatta tcctgtaata
     2701 ggttatattt gaatttcaat ataaaaaaat taattattat aagataaaca atttttttgt
     2761 taagaaataa taaaaaaaat ataataaaaa aatatcaaaa ataaaactaa ttataagaca
     2821 taaatttaca ataaagttac atttgattaa attccttgtt taacaaaagc tattcaaata
     2881 taatctaagg tagttttgaa atgggaactc tattatgtaa aattaagtta gtgttaaaat
     2941 gaggtgaatt tatgggcaga agagctacaa gagtttcaag attaggtaaa gaaaaaaaac
     3001 gaaatattgt aattgtattg gtagttttaa tcatagcaat gggtggattt acttattttt
     3061 ttaacagtaa atttctgtac aatgggaaaa tcgctaaaaa tgtatatata gaaggagtaa
     3121 atgtatctga tatgactaaa tcagaagcat taagagctat aacagataag tatactccag
     3181 aagatttaaa tcttacttat gatgggaaaa aatatacaat atcaccaaaa gatattgatt
     3241 taaaatatga tacagaagat gttgtaaaag atgcttatga aagtacaaaa aaagggtcct
     3301 attttcaaaa cttaaaaaaa tatattgata taagagtgaa taaggcaaat atgaagataa
     3361 aagctgaata tgatgaggca aagcttagtt cgaaggtgtc ttctatagca gatagtataa
     3421 atgttaagat gaaaaatgct tctattagcg ttggaagtgg tggactaaat tatacagact
     3481 ctgttatagg tagagaattt gatttggcag caaataaaga gtctatatat aatatgataa
     3541 aaaataaaga gcataaaact ttagaactta aagtaaatct tcaaaaacca gatataacaa
     3601 ctgagcaagt aaaaactgta aattctgtta taggtcaata ttcaaccact tattcacaag
     3661 ctgtagaggg taggtcatat aatgtaggat tatcagcaag aaaaactagt gatgtattac
     3721 taatgccagg tgaagaattt tcatacaata aacttacagg acctagtaat aaagcaaatg
     3781 gttacaaaga tgcacctgtt atagtttatg gtaagctaga acaatcagca ggaggaggtg
     3841 tttgtcaaac atcttcaaca gtttataatg ctgctcttct cgcaggtatg gagataactc
     3901 aagttacaaa tcattcatct gcatccactt atgtacctaa aggtagagat gctactgtta
     3961 gtgatggggg attaaactta aagtttaaaa atccatataa gcatcctgta tatattaaaa
     4021 attatgcagg tggaggaagt gtatcatcag taatctatgg taattctggt gacaaaccga
     4081 atatatctat agaggtaaaa caaactggtc agaataaata ttctacatat cgaatattta
     4141 aagattcaag tggaaaggtc ataaaaaaag aacatatatc aaatagttct tataaagaat
     4201 taaaaaaata aataattttt tagaaaaata tttgtaatat aaaaacaagg aagtttataa
     4261 cttccttgtt tttttgtaaa aatcaacact attagttctt gttttaatat tacaatcatt
     4321 aatatataga aaatattcct atatattggt ataattgtaa atagatttag ttatataaaa
     4381 tgtatgagga ggtgacatgg ttgaatttta taggcaatag atatgaggta gtaaattctg
     4441 atgacgtttt agaaattaac aaaatctata aagctagaga tgttttttac agaaaaaatg
     4501 ttctaataaa agttataaag cacaataatt atatctgtga agattttgtt tcaaatttaa
     4561 ttgatgaaag tactgcttta gatgagataa actctcctta tatactaaaa ataatagatg
     4621 ttgggattca ttgtacagaa gaaacaacat tgtattatgt tgtaagtgaa gactttaatg
     4681 gtatcggact agatgaatta attctaggta attatcttca tttagaagca attgtaaaca
     4741 taatgataca agttttaaaa gctttagaaa tgatacatag gaatcattca tatcatggta
     4801 gtttaaaatc aagtagtata atagtagata cagaatacaa tataaaaatt tgtgattttg
     4861 gaattacaaa agcaaataat ggggttaata caagaagcta tggaaacagg agatatttat
     4921 gcccgcatca actatgtata aattataccg ataaagaaag tgattttttt gcaacaggtc
     4981 ttattctatt tgaatctata tttaaaaaat tgccatttgg agaatcaaat ttagaagaaa
     5041 aaatgttaca atctattgat aggggattag actggaatag tataaaagca attaatggaa
     5101 atacagaact tataaatgtt ataaaaaggc ttcttggaag aaataacaag tatactagag
     5161 ccaatgatat tattattgat ttaagtaaag taatgtatga aaaagcatat atagaagttg
     5221 aagatgagaa agaagaagaa cagaaacaag ataaagttgt acaggttaaa aaagactata
     5281 aaagtaaaat gagaaaaaaa ttacataaaa aacttgttgt tgctggtcta gctatagtca
     5341 tgatttcaat gattattatc agttccataa tataaaaatt gtatattaag cattttaaaa
     5401 tcaatatcta taaatgatat acatagaaat tttagtgtag tcttaaatta tgaaaggaag
     5461 tggttattat gttaacaaaa aataatgagg tattaaatgt ttaggagtat tttaacaaat
     5521 agccacctgc ttttacagtt tagaataaaa aagctgtggc taaaggtcac agctttttgc
     5581 tactttttaa aggcaggagc atattaaaaa ggagcaaatt atgagtaata taaaaataat
     5641 agcaagcaat aaatgttgga ttgaagatat agcaaagaaa caacttgaag atatttcaaa
     5701 gttaaatgga attttaagag tagtaggatt acctgactta catgcaggta aaatacctgt
     5761 aggtttagca gttgagacta aaaatattat ttatccacat ataattggaa atgatatagg
     5821 atgtggaatg actttattta aaactgggat tctaaaaaag aaatttaaaa aagataaatg
     5881 gattaagtca cttagcaaga ttaaagattt gtctgatata gaaataaaaa acacatataa
     5941 agaagaatgc ccaattttaa atttaggaac tatagggagt ggaaatcatt ttgtagaaat
     6001 tcaatgtata agtgaaattt ataataaaga acaatttgaa caattaaaat tttcatctga
     6061 tgatattatg atgttagttc actgtgggtc aagaaattat ggagaagata ttttaaaaaa
     6121 attttatgct aaagacggac ttgaagttga gagtgagaaa gcgatagatt atattaaaaa
     6181 ccatgataat gctttaatgt gggcagagcg taatcgtgaa gctatcagta aaaaaattat
     6241 gcagtcaata ggtacgtctg gagatgttga aacaatattc tctataaatc ataactttat
     6301 agagaaaagg gaagataaat ttatacatag aaaaggtgct gtttcaagtg aaagaggagc
     6361 tgtgattata ccaggctcaa gaggtagtct atcatatata gttatgccta ctgaaaatac
     6421 aaagatatct ttatattctc tatcacatgg agcaggtaga aaatggtctc gctcagtttg
     6481 taaatctcgc cttaaaagta agtataataa agatactata aaacaaacta aatttaaaag
     6541 tcagattata tgtagtgatt taaatttatt atttcaagaa gctccagagg catataagaa
     6601 tatagaacaa attattgaaa gcttgatgga gcacaaactt attcaagtgg tggcaactat
     6661 gaagccattg attacttata aaggataatt ttgaaagcaa aaaaattaaa ataatattat
     6721 agctagtcaa taataaaacc tataaaaatg ttttattatt ggctattttt tctttgtaga
     6781 aatgataatt ttgagagtta aattctctaa catatatatg gttacaaagt aaggctatat
     6841 taaaaattga atatacatga attgatgcca gcataaatga tttcaaaata taaattaaat
     6901 aataaatcta tttttaatat gtaaaaatgt caaataaatt atttttattg acatgaatat
     6961 ctagtttatg aaataatatt aggagcactt atataagtgt ttaaataaga gtagaaaagg
     7021 agcagtgttt tatgaaaaaa aatactaaca ttaatgagtc cggagttaaa cttcttaata
     7081 aataaggagt ttgatgtata gtaactcctt atttattaag tcgtttacaa aataatcatt
     7141 atcaaaataa atggtatggt gatttaaaaa ccaatgactt ataaataaag gagaaaaaat
     7201 aatgaatagt aatacatttg aaagattaca actaaatgaa gttaaggaat taataaaaat
     7261 acattgtgta agttcgcttg ggaaaaattt aatagataaa ttaaatccta gtggcaatat
     7321 tggagtagta agaagaaagt tagcagaaaa taaagaggct agaaagataa ttgaaaatag
     7381 caatcatgta ccacttgaag gattgtttaa tgcaggttct actatagata aaattgaaaa
     7441 aggaatggta atagaaccta ttgaacttgt aaacattgaa gattttttaa gaggttgtag
     7501 gaagatgaaa gcttttatgt tagaaaaaga attttattca cctacattaa gttcttatgc
     7561 tttaaatata acagaatgta aaaatataga agatgagata aattactgta taaagtctaa
     7621 taaagttgat tctaatgcaa gtaaagaatt aaaaaaagta agacgaaata tagaaattac
     7681 agaagcaaag ataaaagata gattaaataa atttataaca tcaactgtaa ataaaaagta
     7741 tatacaagag tttataataa gtaaaagaaa tgataggtat gtaataccaa ttaaatcttc
     7801 ttataaaaat gaagttgatg gtactatatt agatacatca tcaaaaggaa atactgtatt
     7861 tattgaacct attagtgttt caaatttaag tacagagtta attatgctaa aagctgatga
     7921 aactattgaa gaatacaaaa tattatctta tttaacagaa cttatatttg agaagataag
     7981 tcagataaaa ttaaatatag agatactttc agaatacgat atggtatttg caaaagctaa
     8041 atatagtcaa aaaataaaag gaattactcc aaaaataaat aataatggct atataaaaat
     8101 aattaaaggt aaacatccac ttctaacagg agatgcagta cctttagatt ttgaaatagg
     8161 caaaaattat agaagtctta taataacagg tcctaatgca ggaggaaaaa ctgtaaccct
     8221 taagactgtt ggtctgctaa ctttaatggt tcaatgtgga tttgatattt ctgcaaaaga
     8281 aggtagtgaa tttagtgtat ttgaaaaagt ttttgtagat ataggggata atcaaagtat
     8341 tgaaaatgcc ttaagtactt tttcatcaca tataaaaaac attgcagaga ttatgaactt
     8401 atcaaataat tctacccttg ttctgtttga tgaaatagga agtggaactg aacctaatga
     8461 aggagctgga ttagcaatat cattattaga agagttttac aaaatgggat gtataactat
     8521 agcatcaact cattatggag agataaaaaa gtttgctaca ttgcatccag agtttgaaaa
     8581 tgctggtatg atgtttgata aagaaacgtt agaaccatta tataagttaa ctattggaaa
     8641 atctgaagat agtaatgccc tttttatttc taaaaaaatg ggaataaaaa atagagtttt
     8701 agatagggct aaagaatatg taattgatag aaactacaat ttagatttag ttaaaagaag
     8761 taagctacaa tctaatgttg aagacaaaaa tagttctgaa gtcattttaa actatacaga
     8821 ttataatgta ggggataagg taaaattact agatgaagat gattttggaa ttgtatataa
     8881 gcctatagac aagtttaata atgtagaagt attgtttaat gataatttta tttcagtaaa
     8941 tataaaaaga ttacaactta gcataaaagc atcagaattg tatccagaag ggtatgattt
     9001 agatacatta tttactaatt ttaaagaaag aaaattggaa aaagatattc aaagaggttc
     9061 aaaaaaagct cttaaaaaga ttcagaaaga aattagagag aatagaaaat aaatataaaa
     9121 aacataaaag aaagcaatct aaagagcaaa ttttatcttt agattgcttt cttattaaca
     9181 tatcttaata aacccaatga ctaacaagat taagccactt agccaagata agtttaaatt
     9241 tatgttttta acaaacatat ttcctagtaa acaaccaaat aatactgcaa ttatatttga
     9301 tattaaagaa aatagaataa cctgtatata attcacacct acaagaccac taccaaaacc
     9361 aatagctaat ccatctaaac ttaaagcaag tgcaagtgta aatgcttcag cagatttaag
     9421 cactttagat ttgcttgtat ctaagacgtc aggttcaata cttacattaa aatttaattt
     9481 aaggtctaac atattaaaat tataattctt tgagtgtata gattttttct taaaataaga
     9541 tttaaaaaag ctttcaatta gtctagcgct tcctaaaaaa aataagataa agaaacatat
     9601 tagcattgtt atattttgag gtaaaaagtc tctaactatt gtacctgcaa aaagcgatat
     9661 tgccaaaata gctgaacaaa ctacgctgat aattatattt gaatataagg gaactttaac
     9721 tttatttacg ccatatccaa agcttgtcac aaaggcatct atacaaagag aagtaactaa
     9781 taaaattgat tcaatcacag tagattaaca tcctttctct taaattttat acttatatta
     9841 gttatagtat tgtaaaaatg gataaattgt tacagataat ccaataaatt gttgataaaa
     9901 tttcaacatc atacaacacc taaataaaaa aagaatcata tcatataata atataaaacc
     9961 aatcataata aagcaggtga aaataatgga acaacatagc aaggttggga atttcggtga
    10021 tttgttgaag attttattag atgaaaaaga attatcaatg ggagaattaa gtaaaaaaag
    10081 tggaattgat aaatctacta tatctcgtat agctaataat aaacaaaagc caaatataaa
    10141 tcatttagaa aagatggcaa tacatttaaa tattaaccta gaagaactgt tgaaagcttc
    10201 aggatatgaa tttaaaaaca ataataatca aatatttaat acagatagtg attttagtaa
    10261 ttttgatgat attcttggat ttgcaaattt aatcaatgat aagaacttta atggaaatat
    10321 tgaaaaagag ttaagtaagt gtaagttgta tgtccaaaca gatgaaggta aaaaattact
    10381 ttttgataat tttaataaaa aaatagattc tattgaaaaa caagggcaat tcacagatag
    10441 attaagacaa atgtatgctg atttttgtac agacggactt acaataaaga aatatttatt
    10501 gattggaagt atgctacttt actttgttat atcaacagat gtaattccag atttcgtgtt
    10561 cccaatagga tttatggatg atttagtggc attaaatata gttacaaaat tacttaaaaa
    10621 tgataagtaa gttttagaat catattaaat atataaataa aaatatataa aagttattat
    10681 tttttataag aaacaaatta aaagtacaag aaacagatta aaaatttaaa actaagaatc
    10741 taatatatat tttgtaacta tttaagtata taaaataaaa taatatccaa actaatacaa
    10801 aatagtaata attgttttgt actggaggat atttatgaat tgtaaatgga tatctaaaat
    10861 agatgagaga aaaaaatgtg atagagaagc agattcttct ggatattgta tctttcataa
    10921 agaaaataaa tctgatgaag agatacagtt gatggtagat actcttaata aagaagaaat
    10981 aagtgaattt aatggatttg tgtttgaaaa tgaatttaat gctgaagaaa tattaactta
    11041 caattataaa atactggatt tttctgaatc catatttaaa caaaaagcaa attttaaaaa
    11101 atatattttt aaaaagaaca ttatttttaa ttatacagaa tttaaagata aagtgttatt
    11161 taatggttgt gtattcttag aaaactgtga ttttaataga accatattta gtaaagacta
    11221 tataaatgac cgtatatttg aaaaagtgaa atttaaaggt tctgatttga tagttaataa
    11281 agtagaaaat tttccacgaa tggatggaat aatttttagt atgtgtacaa agtttgtgtt
    11341 aaagaatgtt gaatatggaa aaagtgagta tgagcatggc aagataaatt atagaatagc
    11401 tagaaatcaa gcaacaaaaa ttggagaata tgagatgata ggattttact attataagga
    11461 aagaatttat agtagtaaaa taatgaaacg ttctaattat cctactttca gtgactattt
    11521 ggttgaaaaa ttttttgacc aaatagcacg ctacacgaca ggttatggag aaaagccatg
    11581 gaatatatta ttagtgatta tagtgataat aagtgttttt gccttattat acttatttgt
    11641 aggtatagaa agttcaaata gtacacttgt agctttagat ataaacaata taggtgatta
    11701 ctcactaagt gagattttca gaatgtatat ggatttatgg tattttagta tggctacatt
    11761 tagtacagta ggatatggag atatggttgc tacaagttta attgggaaag cattagcagg
    11821 catagaagta ttttttggag ttacaatagg agcaatttgg gcatctgtga ttattaaaag
    11881 aatgataagg taatatctgt ttaaatatag ataggtatta attactagat ataaattgga
    11941 ctaaataggg aaaatttaaa tataaatata cttaataatc caagaaggtg aaaaatttga
    12001 aaaatgcact aaaaaaaatt atatcattag ccatgattct agtttttata ataccaaatt
    12061 attcatatgc agatgataaa tctgtagaca aatattcaaa aacatctata cttatagacc
    12121 aagaaacagg tagagtttta tatagtaaag aacctgatat gaaagtacca ctagctagtt
    12181 taagtaagat gatgactttt ttacttgcaa tagaagctat tgaaaataaa gaagtaaaag
    12241 aaactgataa ggtaaagata gacaaatcta ttgcatcagt aaaagggtca agttataaac
    12301 ttaaagatgg tgaagaagtg ccacttatag aacttatgag aggtcttatg attgtatcag
    12361 gaaatgatgc agcaattgct atagccaaac atatttgtaa aacaaaggaa gcatttgtgg
    12421 atagaatgaa taaaaaagca aaagaaatag gaatgagcaa tacacatttt ctaaatccaa
    12481 atggtcttcc aatatacgat ttaagtaatc ccaaaaaacc agcaaaagaa aatatatcta
    12541 ctgcaaaaga tatagctatt cttggaaaat acatgtttga caattatgaa aaacaagtaa
    12601 cagctataac tgatatggag acatatacaa attcagatag aagttttgaa aaaagcaata
    12661 caaatgcatt attgagaatt ataccagaag tagatggtat aaaaactgga tatactggca
    12721 atgctggata ttgcttatca ttttctatgg ttgtaaataa aaatgataaa aatgagaaaa
    12781 aacgtagagt aataggagtt gtattaggta ctaatcataa aaataaaaga acatctgctt
    12841 cattagctct actaaaatat ggaaaagaaa atttcaatat gaaaaaagta attgataaag
    12901 atagctttat tggtaagaaa tatataaaag gaatgaaaga gctagaggtt acattaaaag
    12961 caaaagatga actttataca atattaaaag atgatgaaag tataaaatca gaagttaaga
    13021 ttaaaaatat agagtaccct gttaaaaaag gcgatactat gggtattata aaatattata
    13081 ctagttcagg tgacttactt ggaagtgtag atatagtaag taataatagt atagataatg
    13141 taccgttaaa aacgaaatta aaaatgaaat ttgcaaatta aattcaaaaa atggtataaa
    13201 atacacaaaa aaatataaaa atagaaaata tggaaaaaat attgttattt cttcacctct
    13261 gtgatatact actagaggtg aaaaaataaa ataaatcaca cacagcattg ggatccttaa
    13321 aaggtgccta ttacatggtt ttttagggag aagatcaagc tggaggtata aaaccaggag
    13381 gtaagatatg tcagtaatat caatgaaaca attattagaa gcaggtgttc acttcggtca
    13441 tcaaacaaga agatggaatc ctaaaatggc taagtatata ttcacagaga gaaatggaat
    13501 atatataatc gacttacaaa aaacagttaa aaaagttgaa gaagcttaca aattcactaa
    13561 agaagtagct gaaacaggaa agccaatctt attcgtagga actaaaaaac aagctcaaga
    13621 tgcgataaaa gatgaagctg aaagatgtgg aatgtacttt gttaatgaaa gatggttagg
    13681 tggaatgtta acaaaccaca aaactataaa aacaagaata aacaaattaa gagaattaga
    13741 aaaaatggaa gaagaaggcg tatttaatgt tcttcctaaa aaagaagtta taaaattaag
    13801 agctgaaaaa gaaaaactag aaaaatactt aggtggaata aaagacatgc ctgaattacc
    13861 aggtgcaatg ttcgtagttg acccaagaaa agaaaacata gcaattcaag aagctcatag
    13921 attaggtata ccagtagttg gtatagttga tactaactgt gacccagaac aattagactt
    13981 tgctatacca ggaaatgatg acgctataag agccgtaaaa ttaataactg gtgctatggc
    14041 aacagctgta attgaaggta gacaaggtgc tgaagaagaa gtagctgaag accaagaata
    14101 ataatttgac aattaaatgg taagggtcgc ccttaccatt tataatatgg aatagaataa
    14161 gtaggaggaa acttaaaaaa tggctaatat aactgctcaa atggtaaaag agttaagaga
    14221 aagtacaggc gcaggaatga tggactgcaa gaaagcttta caagaagctg aaggaaacat
    14281 ggaaaaagca gtagatttat taagagaaaa aggattatca aaagctgcta aaaaagctgg
    14341 tagagttgct gctgaaggtc tagttgcaat agaaatgaat gatgataata cagttgcttc
    14401 tatggtagaa gttaactcag aaacagattt cgttgctaaa aacgaagact tcaaagtgtt
    14461 cgttaaagat gctgcttgta tggcattagc tactgataaa gaagatatag cttctttatt
    14521 aggtgaaact cataaagagg gaataacttt acaagaagtt ttaaataata gggttgcaaa
    14581 aataggtgaa aaattagact ttagaagatt tgctaaagtt gtaactaatg gacaggttgc
    14641 tggatacatt cacggtggcg gaaaaatagg tgttcttgtt gaaatggaaa cagaagctag
    14701 agatgctaaa gttttagaat taggtaaaga tgtagctatg caagttgctg ctatgaatcc
    14761 taagtatgtt tcaagagatg aagtagatgc tgaatacata gcacatgaaa cagaagtatt
    14821 aactcaacaa gctttaaatg aaggaaaacc agctaatata gttgaaaaaa tggttaaagg
    14881 aagattagaa aaagaattaa aagaggtttg tttattagag caaactttcg ttaaaaatcc
    14941 agatataact gttaaacaat tagttgctga tgttgctaag gcagtaggtt ctgatataaa
    15001 agttgttaaa gttgtgagat tcgaagttgg tgaaggtata caaaagagag aagaaaactt
    15061 tgcagaagaa gttgctaagc aacttaagta ataaccaaag agagaacacg caggtgttct
    15121 cttttttaaa aaatagaaaa aatggatatg aaggattgaa ataggaggtt tctgatggat
    15181 aaaccaatgt acaaaagggt attgttaaaa ttaagtggag aagcattagc aggagaaaaa
    15241 ggttttggta taaacaatga tgtagttaat gatattgcta ttgctataaa aaaaatacaa
    15301 gaaataggtg ttgaagtagc tgtagtagta ggtggaggaa acttctggag aggtagaact
    15361 agtgaaggaa tggatagaac tactgctgac tatataggaa tgttagctac agttatgaat
    15421 gcaatggcgc tacaggatgc actagaaaat atagatgttg ctacaagagt tcaaactgct
    15481 atagacatga gacaaattgc agaaccatat ataagaagaa gagcagttag acacttagaa
    15541 aaggaaagag ttgttatatt tggtgcagga acaggaaacc cttactttac aacagataca
    15601 actgctgctt tacgtgctgc tgaaatggaa gcagaagtta tcttgttagc taaaaatgtt
    15661 gatgcagtat atgacaagga tccaaaagta catgcagatg ctaagaaatt tacagaatta
    15721 agttacatgg aagtaataca gaaagaatta aaagtaatgg attctacagc tacatcttta
    15781 tgtatggata ataaaattcc aataaaggta tttgagctta caacagagaa tataataaga
    15841 gcagtaaaag gcgaaaatat aggaactact gtaaaataat gaagaatgaa ggaggagtaa
    15901 aattatgaaa ctagaaatac ataagcaatt agaagagaaa atgaatggga caattgatgc
    15961 tttaaagttt gaatttggaa ctataagagc aggaagagcc aatgcacaaa tgctagacaa
    16021 aataagagtt gattattatg gaactccaac tccaataaat caaattggtg ctatatctgt
    16081 accagagcca agaatattaa tgatatctcc ttgggataaa tctgctatgc atgaaataga
    16141 aaaagctata gctaactcag acttaggatt aaatccatca aatgatggtg aagttataag
    16201 actttctgta cctgctttaa cagaagaaag aagaaaagaa ttagctaaaa aagctagtaa
    16261 agctgcagaa gactttaaag ttagaataag aaatgaaaga agagacgcca acgagaaaat
    16321 taaaaagatg gaaaaaggcg gagaattaac tgaagatgaa ttaaaaaaag cacaagatga
    16381 agttcaaaaa atgactgata aatttataaa agaaatagat acattattat ctaaaaaaga
    16441 aaaggacata atggaggtat aatattgaaa aaatattata accttttagg tcttcatgta
    16501 gatgaggtaa aacaatattt tgatgagcaa gatataaatt ataccataaa atctattgaa
    16561 ggtaaaaagg ataaagataa acttgtagtt cctagagtta taaaaatatc tgagataggt
    16621 gatagtgtag aactgataat cacatacttt tctgactcct tagtttaagg agtcagaaca
    16681 atattggagg caaaatatga ataacaacat tatatatgat atagacttaa ataacatacc
    16741 tactcatatt gctattataa tggatggaaa tggaagatgg gcaaaggcta gatttcttcc
    16801 aagaactgca ggacataagg ctggagtaga aactataaga gatatagtaa aagaatgctc
    16861 aaaattaggt gttaagcact taacattata tgcattttca acagaaaact ggaaaagacc
    16921 gaaacttgaa gttgacacac ttatgaactt attatctaca tacttaagaa atgaaatagc
    16981 tgaacttcac caaaacaatg taaaagtaac tgctatagga gatataagtg ctttaccaaa
    17041 aacttgtata agagaattaa actcagctaa ggaactgaca aaaaacaata caggagttaa
    17101 cttaaattta gcattaaact atggaagtag agcagatata aaaaatgctc ttatagatat
    17161 agtaaaaaat tgtgaaagtg gtaaaataga tataaacaat attgatgaag atattataaa
    17221 aaactattta agcacaaagt ctataccaga tccagacttg gtaataagaa caagtggtga
    17281 acaaagattg agtaactttt tactttggga ggttgcttat tctgagtttt actttactga
    17341 tatacactgg cctgatttta aaaaagaaga actacagaag gctatatacg tatatcaaag
    17401 aagggataga agatttggag gacttaagta aggagattat tttatgctta caagaattat
    17461 tgcttcacta gctctggttc cattatttct atttgttgta tatggaggga ttcctctata
    17521 tatagctgag acagcaatag tttatattgc attacatgag ttttataagg catttaaaat
    17581 aaaagatgta aatccaatat tcattatagg atatttattt tctatttatt tagctgtaaa
    17641 aaatattttt aatttaccat tggaatatac ttatgcagta atttttattt tatttttagc
    17701 aagtataatt tatatgttga tgggcaaaaa caatgttata gatgtttcga ttacgtttct
    17761 aggagttttt tatataggag tatttttaga ttttataatt ataactataa atgaatttga
    17821 aaaaggcagt atatatgtat ggcttatatt tgtgatatct tttatgacag atatatttgc
    17881 atattttagt ggttatttac ttggaaaaca taagttaatt cctaaagtta gtcctaaaaa
    17941 gactatagaa ggagctattg gagggataat aggaagtaca ctttgttgta ttttatttgg
    18001 atatttattt ggtattgatt tgcttcaatt agcgataata ggaagtatag gaagtgtaat
    18061 agctcaatta ggggatttat ttgcatcttc tataaagaga tatgtaggga taaaggatta
    18121 tggaaagata atacctggtc atgggggtat attagataga tttgatagtg ttatattagt
    18181 tgcacctttt gtatatagtg cgattaaatt ttttattaga taaagattgg ttggatataa
    18241 aagagcaatc tataattgct agtaatgaaa atagctatgt aacttttaaa agtagagata
    18301 ttctgcagtt attagttaca tggctatttt cattgtttga taatttagaa aatattaagg
    18361 aaattttata aaattataga gtactttata gaaatatact atatttgtag tatgaatatt
    18421 ttatataaaa gaactgtttt caaaaagtat ttttttgttt aataatataa atattattaa
    18481 ctttattatc cttttataat ctatataact aaatataact aatttattat ctatttataa
    18541 attttatttt tagacataat taataagaga taagtagatt attgtattta ttgtataaac
    18601 ataggcgtaa ttcaagtaaa atttcaaaaa aaaggaatat atttccataa tatgataaaa
    18661 taaattcaaa gagttaaatt ctagtcaaat attactttaa ttatttatta aaatagatta
    18721 gatattccat attcaatacc attgagttga tgtgtataat tttaaatatg taaaggattc
    18781 tatggggtat gtatttggag ataaaatatt aattgattta gctgaatgtt taaaaagata
    18841 ttttagagaa acggacactg ttggtcgtgt aggaggtgat gagtttataa tatagtgaag
    18901 aaagagaaag tgtaaaaaat aaaggctttg ataatattaa aaaggctgga caataagttt
    18961 acgtatgatg aatgatattt tgagataagc gtaagtatag gaatttcttt atattcaaaa
    19021 tatggagaac agttttataa gttatatcgt catgcagata gtgctctata tagagtaaaa
    19081 taagaaggaa aaaacacgta ttgtatgttt ttctatctaa aaataaaatc tatattataa
    19141 aggattgttc tatcttaggt atataaatga ttgagatatt taagataaat acatattact
    19201 gcaaagcatt gataattatt tttgatgaga gattgattat ttgcaaatta tatagataca
    19261 ttataattga gggaataata atgaagaaaa aatatgattt tttaatttat gctgctattt
    19321 ggctagttgc tattattatt tttatatttt ctctatacca tagtatagag catattaaaa
    19381 ttataaatta tactggtatt attagcagtg aaactcaaaa agttactaaa caagaattaa
    19441 ataataaaag aaatgacaaa ttgataagtc aactagatag tattttaata gaactaagga
    19501 caggcaatgg gaaacatagg ttgcaaagat gtgataataa agaatttcaa gaaaaattaa
    19561 ttgaaatgga tgctatgtgg gattctatga aaaaagaaat tagaaaagtt agaaatggtg
    19621 gttcaggtga taaattatac aaattgagcg aaaagtattc ttcgttgtct aatcaagttg
    19681 tttttatatc tgaaaaacat tctgatataa aactgcattt ttttgccact gtattattta
    19741 tttatcttat aatttcaaca ataagtctct tgatttggga atattacaat aaaagaaaat
    19801 ttgacaaaat attttatact gataatttga caaaaataaa aaaccaagtt gcatttgaaa
    19861 atagagctat tgaaatttta tctcatgcgt ataataagga gtatgtgcta ctaaacattg
    19921 acattgataa ttttaaatat attaatgata cacatggata tgaatatggt gataaagttt
    19981 tagtaatagt tgcaaatgta cttgccaaaa cttttaatac taaagaaact tgtgcaagag
    20041 ttggttcaga taattttgta atacttgcaa aatatagaga atctctctta tatgagatta
    20101 gtaaaactct aactgatgca ataatatccg aattaaatat gaatgtgaca caaactatat
    20161 ctttttgtat aggagcatat ttagttgaaa ttgaaaaatc aaattataaa tatataaatt
    20221 ctataatgga taaggcaaat attgcacata aagtaagtaa aatgagagga atttcatcta
    20281 cagtgtggta taatgaaaat ctattaaagc aattacaaat ggaaaacagt atctataatc
    20341 atatgtataa agcactagag aatgaagaat tccagatgta tttgcaacca aaatttcaaa
    20401 tatcttcttt aaatgttgta agtgcagaag ctcttgtacg atggttttct ccagaacttg
    20461 gttttttgtc accagatcaa ttcattccac tatttgaaaa aagcggattt attattgaat
    20521 tagactttta tatgttaaag aaagcttgtt cattcataaa aaaaacattt atgaaaaaaa
    20581 ataaatatac ttatcccata gcagtcaatt tttcaagagt tactatttat caaaatgatt
    20641 tctaccaaag gtttttggat actgttagag aatatgaaat tccttttaag tatatagaaa
    20701 tagaggtaac tgaaagtgct tttaatgaaa tatctgagcc agttatttca attttagata
    20761 agcttgaaaa gttaggtttc ttaatttcta tggatgattt tggctcagga tactcgtcat
    20821 taagcctttt atgttcttta tcgattaatg gattaaagtt agataaaagc ttacttaaag
    20881 agaaatttaa tagagcgaaa gtatatagta ttattaagtg tattatcgaa atgtcacata
    20941 gtatagatat gtctattgta tgtgaaggta ttgaaactaa aaaagattta gagtttttaa
    21001 agacagttaa gtgtgatcta gggcaaggat tttatttttc taaacctata gaagaaaaag
    21061 aattttttaa taaatatgta atggacaaac aatataatta gttttattgt taatcttatg
    21121 cattgagtta ttttatatct tattaaatag ctcaatgcat agttatgcag gtcaaaaaac
    21181 ataaatcatt caaaatattt cttatattta tataaaaatt cttctatatt ttttgattgt
    21241 tcccatattt caactgcatg tacatcaagt aaataaagta tggaatcatc cacaagttca
    21301 acatattcgc catcttctga accaagtgca tgtcttttga ttttcaatcc tttttcttta
    21361 tagtattttt ttgtttctct atatagtgat tctcgttttt gtatatagtt ttttacttca
    21421 ttatttggaa aactatatga atctaccaat gtctcaccat ttataaaagt tttatcagta
    21481 gcaacttttt catcccagca atgtatttca tcccaagtaa aaaatatctc agttccatct
    21541 ggaataaatg aaaatttagt aataatatac aaataattat tgaaatttac ttcataatat
    21601 tcaggaatat cttcaaattc catatagtaa tttgtataat taaagttact actatctttt
    21661 tttacaaatg gtattttctc aataaattta tgtatagatt gttcattttt aaaaattcct
    21721 atatcatagc ttctttcaaa ttgattaatt tt
//
LOCUS       DBGJFK010000066        21708 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.066, whole genome shotgun sequence.
ACCESSION   DBGJFK010000066 DBGJFK010000000
VERSION     DBGJFK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21708
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.066"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(216..1055)
                     /locus_tag="ACOIAP_002782"
     CDS             complement(216..1055)
                     /locus_tag="ACOIAP_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGZ2639661.1"
                     /translation="MSDIKNEVAKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAISGIV
                     GLF"
     gene            complement(1079..1837)
                     /locus_tag="ACOIAP_002783"
     CDS             complement(1079..1837)
                     /locus_tag="ACOIAP_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGZ2639662.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNENVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1894..2367)
                     /locus_tag="ACOIAP_002784"
     CDS             complement(1894..2367)
                     /locus_tag="ACOIAP_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGZ2639663.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNNGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELIAKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2396..2812)
                     /locus_tag="ACOIAP_002785"
     CDS             complement(2396..2812)
                     /locus_tag="ACOIAP_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2639664.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAVIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLNL"
     gene            complement(2858..3910)
                     /locus_tag="ACOIAP_002786"
     CDS             complement(2858..3910)
                     /locus_tag="ACOIAP_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGZ2639665.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGTEVKSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKKLGADICINAKEKNI
                     VEEIKRLTDRDGADIVIESAGTPMTCGQVLLLAKKGGTILYAGVPYGDVVLTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSTGLYHMKKGAMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIGN"
     gene            4306..4986
                     /locus_tag="ACOIAP_002787"
     CDS             4306..4986
                     /locus_tag="ACOIAP_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGZ2639666.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSIKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5116..5436)
                     /gene="sugE"
                     /locus_tag="ACOIAP_002788"
     CDS             complement(5116..5436)
                     /gene="sugE"
                     /locus_tag="ACOIAP_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HGZ2639667.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     regulatory      complement(5506..5612)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            5818..6645
                     /locus_tag="ACOIAP_002789"
     CDS             5818..6645
                     /locus_tag="ACOIAP_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HGZ2639668.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGDLIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGVAICYDIRFPE
                     LSRLMALKGAEIVILPASFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGKIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7438..8112
                     /locus_tag="ACOIAP_002790"
     CDS             7438..8112
                     /locus_tag="ACOIAP_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639669.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNSYEVYTAQSGKDALKKISK
                     NPDIILLDINIPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIDNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETIWGV
                     GYKWIK"
     gene            8100..9260
                     /locus_tag="ACOIAP_002791"
     CDS             8100..9260
                     /locus_tag="ACOIAP_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639670.1"
                     /translation="MDKINNMSLKKVFFVLTLSSLIIASILTTFSYILLNNLYNYIQD
                     KYLKTPINTGFITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIKNLDENISIIAKQEGKSFTLKSQINNVNLL
                     FDENIILRVVENIISNAFRYARNNVSILIYIEQELLTFVIEDDGIGFSKESLKSALRP
                     FYRDKTLNESNAHFGMGLYISKILCEKHGGSISIENNLTNSAKITAKFSTKN"
     gene            9434..10102
                     /locus_tag="ACOIAP_002792"
     CDS             9434..10102
                     /locus_tag="ACOIAP_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639671.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSIIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHSEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            10105..12573
                     /locus_tag="ACOIAP_002793"
     CDS             10105..12573
                     /locus_tag="ACOIAP_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639672.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITLGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLIGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGASENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRGIGAEPNQIYKIVILQILILCTIAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTSISLI
                     FSFISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSILDKIDNM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSTLEDFK
                     NGSICFIKNPLAISTPGVKTKYTNLKPKDNITINKKQLDIYSTVDKMFFLQGNGWVNG
                     VDIIVYDSVYNTLTNKNKFNQINIYAKDKSDLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIELLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAILGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISILAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(12814..14238)
                     /locus_tag="ACOIAP_002794"
     CDS             complement(12814..14238)
                     /locus_tag="ACOIAP_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639673.1"
                     /translation="MKNQSLATQFRRTFIFIIIASIVATVITYVFAFYLFIYSLNKDI
                     YPPNYYERQVPRIKKYIDEKNIALLSQSNEEGLKRTIRGDGMLYQVVDDNGNILYGNN
                     PKKPFKTKEELFNNFINTTVRKGGYIYTVPIKGTNGKIEGAVILFYQVKMTFANSMGR
                     LTFAVIVIAMFSPFLYVIGFTIWLSKQFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKNSLSAQWKMEQERVEMVEALAHDLKSPLSIVLGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNPVPINLPEFLVQ
                     KVQDYELQAHQKDVELILKMYGNIQSPIQIDLDRLTRIFDNIISNSLQYTPSGGNISI
                     IAKAEKNCISYEICDSGSGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(14257..14949)
                     /locus_tag="ACOIAP_002795"
     CDS             complement(14257..14949)
                     /locus_tag="ACOIAP_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2639674.1"
                     /translation="MSKILIIDDEIDLVMLLEDELKAKGHEVLIAYDGQAGIELSKNE
                     PDLIILDIMMPKMDGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFEKLCLYMKERAIKIDGKDIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(15001..15780)
                     /locus_tag="ACOIAP_002796"
     CDS             complement(15001..15780)
                     /locus_tag="ACOIAP_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HGZ2639675.1"
                     /translation="MIKLLSSEWLRAKRTAVQGLTLYMPIIFSLCVVAYLTIKSGSTQ
                     EFAFEGFFTIWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMNIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGAKVWAFVPWTWPVKLGMLPGTYFIKEAGTISTEV
                     FYSKMMQSATVVFIVVAIGLIIFLIGGVIWFKIWEGRKSYE"
     gene            complement(15777..16547)
                     /locus_tag="ACOIAP_002797"
     CDS             complement(15777..16547)
                     /locus_tag="ACOIAP_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HGZ2639676.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QINSWAWESLLALIFNWWSMMFLSIGFALFATLVASQEKKAGNYRALRTHNVSPMTIW
                     INKIIAMAVYSFISTLVLIVVTIMTGLILKAGPIPFGQIIGASIVCWVGSLAILPIQL
                     WLATWKGMFLSMGVGALGMIFGVLAASKPFWVAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(16544..17248)
                     /locus_tag="ACOIAP_002798"
     CDS             complement(16544..17248)
                     /locus_tag="ACOIAP_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HGZ2639677.1"
                     /translation="MKDLIIETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTDGRIIFDRKPWKRESLEKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLNDPELLILDEPTNGL
                     DPFGIQELRELIASFPEKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            18026..18283
                     /locus_tag="ACOIAP_002799"
     CDS             18026..18283
                     /locus_tag="ACOIAP_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639678.1"
                     /translation="MILNRTELFRGYSLDRFNEICNILSVNKIKYKYKVKNNTYSKKP
                     FYNEITLGNLGQKEDFSYEYLIYVHKDDYEQAEALINSKLR"
     gene            18426..19052
                     /locus_tag="ACOIAP_002800"
     CDS             18426..19052
                     /locus_tag="ACOIAP_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGZ2639679.1"
                     /translation="MKINIKSTLNEFIKQNNLFDDNRIISYLPNITIDTDKIKTIMIN
                     EVVPTNTNDDFYSIDKDADYLKTTIPLFNNAGIEVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            19423..19809
                     /locus_tag="ACOIAP_002801"
     CDS             19423..19809
                     /locus_tag="ACOIAP_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2639680.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            19812..21611
                     /locus_tag="ACOIAP_002802"
     CDS             19812..21611
                     /locus_tag="ACOIAP_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HGZ2639681.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSNTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDILNILLLILWIIGILIMIVITIHCNIKIKSMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNRDMLINYIMCFFQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDNHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNKQTMYEDLSKYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRDNSHIPWDGKHHSNISWNEDQDLFSAMENS
                     VNWYFQTLDKKTGIKNIQTYLEQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFNFEDKNIETVKDSLLISKKDGVSLSGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGISASKITLSILNDKKIYNP"
BASE COUNT         7892 a         3532 c         2750 g         7534 t
ORIGIN      
        1 tatatgaaaa tgaaaaagca cctcattctg attaaaaatc tttctgagat actttttaaa
       61 atattaaata ctaaatatag cttatataag cttaaatttt aatctattat aaaattaccc
      121 taattgctaa actttttacc ataagttttc ctacatctta caaatataat caatagatgt
      181 agaatcataa tttacacacc aacatatata tttatttaaa ataatcccac aatacctgaa
      241 atagctccca ctactattaa tataaacatt atttttattg gagaaagtcc tttctttaag
      301 gcaaaaagta ctaataatgt aagtaccaaa ggaattaatc ctggaaatat cttatcaagt
      361 aaatccgttt gaaggctaaa tttaaaatct ccactagtat aacttattgg tgtagacaaa
      421 ttaataaacc tacctacaag tccccccatg actaaagtac ctagtataga agcaccttct
      481 ataaccttat ttactattcc accttggagt atactttcaa cagctttttt cccatactta
      541 tatccattcg tccacattcc aaaagaaatt gaagtcatta ttatatattg agctattaca
      601 aataatatag gccctgcaat tgatgctcct ccctcagtta aaccaataca aacagctaat
      661 actataggag ttataactcc ttgagttaaa gtatcaccaa tccctgctag tggacccatc
      721 aagcctgttt tgatagcatt cataccatct ccacttattt catctgctcc attagctttt
      781 tcttcctcca tagctattgt tattccatgt ataacacatc cacatatagg ctctgtatta
      841 aaaaatgcta gatgagtctc cacttcttgt tttagctctt ccttatctgg atataacttt
      901 ttaagtaccg gtaacattga atgtgaaaaa gctgttgatt gcaatctttc ataattgtaa
      961 ttagattgtg caaagaaaaa ccatcttaac cacgatttta ttacatcttt cttgcttaac
     1021 gttttcttag ctacttcatt ttttatatct gacataatat tttccccctc acatgtattt
     1081 aagatgtagc actatctttt ccgtacttaa ttgaagtaat tgtaagagca agtattactc
     1141 caataacaga tattactatt atatctactt taaaataaac agccattagt attcctaata
     1201 tgaaaaaggg catagtaaat ttgtttccaa tcaattttaa attcatagca attccaagtg
     1261 ctggcaacat agccccaatt acattaaata catgtaacac attctcattc attacttcca
     1321 acataccatc tatcgcattt ggaccaaaat aaacaactaa tagtgctggt ataaagctca
     1381 ttgcaaataa cagtatctgt ggtggtacta tatttataaa tgctactcta tcaacattcc
     1441 ctttttgaac ctctctatca gcccaatgtg caaaaaaaga atttactgtc atctttccaa
     1501 tccaaagtac agttgcaaca gttcccaatg gtacagctat tgccattgca gtacttacat
     1561 ctagcttaga tgctatagct aaagcagtgc ctacatatcc tgcaaaagct gggtctccca
     1621 tctgagctcc tcctgctgat ataaaaccta gatatatcat atttatacct gctcctataa
     1681 ttgctccttg aacagggtct cctaatataa ttcccgttac aaatccagcc aatagaggtc
     1741 tattccatgt aaaaaatcca acataagtca accatggact ccaagaaaga taataaaaaa
     1801 ttgctatcaa tactgcttga attagtgaaa tatgcatact tttcctcctt attttcttct
     1861 aaagatttac aagataatct tctttataaa gctttataat aatgttccta catcaatttt
     1921 ctttgcatct ggtactattt gtataaagca tttaacatcc tttgctatta gctctcgaaa
     1981 tatttctttt tcttcatctg acacagatat atttttataa aaactttttc taccaagtcc
     2041 agctcccata cctccaacat tcaattcctt taaatctacc ccattattta ctaaacctaa
     2101 aacagtttta ggatatttga ccaatactat taaattttca tctccattat gtgattttaa
     2161 aacttcagca cctgattcta catcatgtac ttcaacctta acagttgatg gagctgccat
     2221 ttgtaaaact tgaactataa atgggtcctt tactactaaa tcgtccacga ttactatcct
     2281 ttttgctgat gtaatcttac accaagcagt aataacttgc ccatgtatta atctatcatc
     2341 aattcttgtt aatgctatat tactcataat aattcctcca gatttttaat ttattctata
     2401 aatttaaaac agttttaaca tctttgattc ctgatatccc aacttcctca cataaattct
     2461 tcaagtcttt caacttcata gtatctctgt ttaaaaataa ttctaaaagc ataggtaaat
     2521 ttacacctgt caaacattct aactcacata ccttagcaaa tttatttatt ataacagcag
     2581 atgtattaaa tggagtccca ccataaaaat caagcaatac taaaactcct tcatccttat
     2641 atttctcaat tccatcttct aactttctac taaactcatc tatgctatca ccatggttta
     2701 atcctaaagt ctctacattc tcctgtttac ctactattag ttcagcactt tctaacatcg
     2761 ctttagccat atttccatgt gtagctataa ttattcctgc catatgaatc atacctttct
     2821 taactaaact tttttatatg gattattctt tagtactcta attacctata ttaatcatta
     2881 tcttaccaaa gaaaatatcc cttttatata ctttttcaaa atacgctggt acttcttcta
     2941 aatttattct atgtgttact aatttttcaa cattcatagc accctttttc atatgataca
     3001 gtccagtact ccattctttt cctggaaatg gaaaggagtt tccaaaccaa gttcccttta
     3061 cagttaattc acttcttact atcttttcaa attgttctct agtcaaaact acatccccat
     3121 acggtacacc tgcatacaat attgtccctc cctttttagc taacaacaac acttgaccac
     3181 acgtcattgg agtaccagcc gattcaataa caatatctgc accatctcta tcagttaacc
     3241 tttttatttc ttctacaata ttcttttctt ttgcatttat acaaatatct gcccctaact
     3301 tttttgccaa gtctaacttc tcatcaaata catccacagc tattattttt gtcgagccaa
     3361 atatctttgc ccattgtatt gaaaataatc ctattggacc tgttccaagt actacaacag
     3421 tatctccaac tttagcttct gacctaaaaa gaccatgtcc tgctatacat actggctcta
     3481 gtgcagcagc agtttcataa cttatctcat ctggtatttt tattaaattt ctctctttta
     3541 cctttgtata ctctgcaaaa caacctccaa gttctttatt tcctattatt gctacgttat
     3601 tacatcttga atacaatcct tttttacatt catcacattc aaaacatggc atggctggac
     3661 aaacagcaac tctatctcct attttaaagc ttttcacctc tgtaccaacc tgtgctactt
     3721 ctccagaaaa ttcatgccct aaaatctctc caaccatatg tggacctgtc tttgaatatt
     3781 ttgatatatc agagccacat attccagcta cttttacttt aattattaca tcatcttttt
     3841 ctaatatttt tggtacatct acatcctcca ctcttgtgtc tcttatacca tagaatctaa
     3901 ctgacttcac gattaaccac ccctactttt tatttgagaa tatatactta ttttttatat
     3961 gttaaatatc taaagcaact ttcatgccaa tatatgtaag tattgttttc atgcacttta
     4021 taaaattatc attagatgtg tgtcaaagtg tgtcaaaact tttttatacg aaaacttatg
     4081 tgtgtcaata taaacgacac tcacatttta tactagttct cctattataa gttttataaa
     4141 atgtactttt tttgttattt ttataaaatt gttcggaaat tccccctcta tttgtgatat
     4201 aatattaaat ataaggtatc aatataaatt ttcatacgaa tatcagaact tttttgacac
     4261 taatgcctta ttcaatataa taatttaact ttttggaggt tgtttatgaa aaaagtgtat
     4321 caaggaaaga ctaaagatgt ttttgaatta gataatggaa attacttact taaatttaaa
     4381 gacgatgtaa ctggtaaaga cggagtattt gacccaggcg aaaatagtgt aggtctaagt
     4441 atagatggaa ttggtagagc taatttagag acatctatta agttctttga aattctaaac
     4501 aatgctggaa ttaaaactca ttatgtaagt gctaatttag aagaggcaac tatggaagtt
     4561 ctaccagcaa aagtttttgg taatggatta gaagttattt gtcgttatag agctgttggt
     4621 agtttcttac gtcgttatgg ttcatgtgtt gaagaaggag ctaaactaga ttgttacgta
     4681 gaagcaactt taaaagatga tgaccgttgt gaccctctta taacatctga aggtttagaa
     4741 gctttaaaca ttatgactca agctcaattt gattcaatga aaagcatgac tcaaaaaatt
     4801 tctaacatag ttcgtgatac tatagctgaa aaaggtcttg aactttatga tatcaaattt
     4861 gaatttggat tctacaatga tgaagtaatc ttaatagatg aaatagcatc tggaaatatg
     4921 cgtgtttata aagatggtgt aatagttgac cctatggatt taactgctct tttattagat
     4981 aaatagtata tacatataaa tttcaaatat aataaactta taaataagat aagctatgaa
     5041 gtaaagactt tttaaatgtt gattattttt aaacattttc tcgcctttaa tttcatagct
     5101 tatttaaatt atactctaat tggtagacaa taactttaac cctacaattc ccaccacaat
     5161 aaaacctata catgcaattc ttgatatact aataggctca tttaagatag ccatgcctac
     5221 aatagctgta ccaacagtac caattccagt ccatattgca tatgaagttc caagtggaag
     5281 atgttttagt gctaatgaca aaaaataaaa acttacaatc attccaacaa cagtaagtat
     5341 acttggagtt aatttagaaa atccatgtga attttttagt tgaaaagccc aaaacacttc
     5401 aaacaaacct gcaacaaata aaaataacca tttcataaac tcatccctct tttcaaatat
     5461 atctcttatt tttccaataa aataacctga gaaatattat aaaatatctc ccaggttttt
     5521 gtccttccgt gttcacaaca aaaactatgt tgtgggtttt atctctgacc agaccaatca
     5581 ttaataattg cggaacccta taaaactcta ttaattattc tattttatct ataataatac
     5641 tatcaacata tataaaaaaa gtcaatatat gggttccatc tataataaaa ataactttta
     5701 tatacctttt aatattctta ttcacttctc tccataccca tttaggtcaa tctaagaata
     5761 tctaattttt atttaatatg ttataataac ataaaaatat tgaaaggagt aatttctatg
     5821 aatttctata aaattgcagt atgccagatg attactacag aaaataaaat tgaaaatatc
     5881 aatcatgctg tagatatggt aacagaagct gccatcaatg gagctaaaat tgtagttttg
     5941 ccagaaatgt ttaactgccc atatgaaaat aaatattttc ctaaatttgc tgaagaatat
     6001 ccaggtgaaa caacaacgat attgagtaaa ttagctgaga aacatggaat ttatttagtt
     6061 tctggtagta ttcctgagtt agaagatgga aaaatctata atacttgcta tgtatttgat
     6121 aaaaatggag atctaattgg aaaacatcgt aaaatgcact tatttgacat tgaagttaca
     6181 ggaaaagtta gttttaaaga atcagatact cttacagctg gaaatgatgt cactgtaata
     6241 gatactgaat atggaaaagt tggtgtagct atttgttatg atattcgttt ccctgagtta
     6301 tcacgtttaa tggctcttaa aggtgctgaa atcgttatct tacctgcttc atttaatatg
     6361 actactggtc ctgcccattg ggagttatct ataagaatgc gtgctttaga taatcagata
     6421 ttctatgttg gtgctgcacc tgctagaaat atgaatgcct cctacatagc ttttggcaat
     6481 tcaagaattt cagacccttg gggaaaaatc attgctcaag ctgatgaaaa agaatgtatt
     6541 atttatgctg acattgatag agatttaatt cctgacataa gacaacagtt accacttctt
     6601 aaacacagaa gaactgattt atatgaactt aatactttga aataaaacag aacataaccc
     6661 cataaatcat aaattaagtg ttaaaaaaat ttatggggtt ctcattaatt tgatttaaaa
     6721 ttaatttcat aaaaataata ctaatattaa tttaattaaa taatactaat aatactaatg
     6781 attatgctaa ttatcagtat ttactaattt aatcactatt agttatttct tttattaaat
     6841 atatttactt tttttactta ttatgtcttc tagctttaca tttggattat ggcatctctt
     6901 tctactttta gtcacatctt tctattgaat tacttgctta aaacaccaat acatacatgc
     6961 cagacaatgt tcacaattat gtaaaaatct tgctctacct tattcaatgt tgatattatc
     7021 tctcctaaaa tttcttttaa ttaaaaaaca acattcgttg atatatcgag tatgttttaa
     7081 gcaactgaaa aaaacaataa taattgatat atcaactaat taatgtagat taattcattt
     7141 ttataattta tatacttttt aaccttttta attaaatcct tcctttctat ttatccattt
     7201 taaacttaaa ttataagatt tcatcagctg tgtttttgca ttccaataag tattaaatat
     7261 caaatatata ttctattaaa atttctaata atttcatcct tgatttattt aacatataaa
     7321 aatatactaa ctttaatgat taagttttga aatataacta agaatttgag aatttattga
     7381 gatttttata ctaaagtata catactatac aaacttaatt tagaagggag cattcttatg
     7441 aacaataaaa tactcgtcgt agatgatgag gaaggtataa taacactctt aaaagattac
     7501 tttgaaatga atagttatga ggtttacact gctcaaagtg gaaaagacgc attaaaaaaa
     7561 atatccaaaa atccagatat tattctactt gatataaaca tccctgaaat agatggaatt
     7621 gaagtttgta atagaattag agattatgta tcatgcccta ttctatttct tacagctaga
     7681 attgaaaata ctgacaagat aaatggtttt cgtgctggtg ctgatgatta tattgtaaaa
     7741 ccttttgatt tagacgaact tggagctaga gtatctgccc atttaagacg tgaacaaagg
     7801 aagtcaaatc aaactaaaat taaattttat aatgatttaa cgatagatta cgaaaaaagg
     7861 ttaatttgta tagataacaa tcagatttca ctttcaaaaa aggaatttga tatagtagaa
     7921 cttctctcta tgaatcctgg acaagtattt gataaagaaa aaatctatga tagagtttgg
     7981 ggatacaata gcaatggaaa tagtgatgtt ataatggaac acattagaaa gatacgaatc
     8041 aaactatcaa aacatactct tgaaaattat atagaaacaa tctggggagt tggttataaa
     8101 tggataaaat aaataatatg tcattaaaaa aagttttctt tgttcttact ttatcttcac
     8161 taattatagc atcaatactt actactttct catacatttt gcttaataat ctatataatt
     8221 atatacaaga taagtattta aaaacaccta taaatacggg ttttataacc atagttcaaa
     8281 acaatgtgaa ccaatttagt gattatgata aaacgttact taatataatc aacatacttc
     8341 agcttgtact tccacttata ttttttatag gacttttatt attagctgat ataatttttt
     8401 acaaggtaaa actaaaaaca cccatagaaa tactcaataa aggtgcaatg gaaatatcca
     8461 acaacaattt agacttttgt ttagaatata ataataatga tgaattaggt aatctatgta
     8521 atgcttttga aaaaatgagg tctgaactaa ataaaaacaa cataaagatg tggactatga
     8581 ttaatgatag aaaacaactt aatgctgctt tttctcatga tttaagaaat cccctaacag
     8641 ttctaaaagg ttactcaaac tatttaacaa aatacatacc aacaggcaag cttagtgatg
     8701 agaagatttt atcaaccaca cagcttatgt ctgagcatat taacagaatt gaatactatg
     8761 tagaaaatat gagtaatgcc caacgattag aagacttagt tgtttcaaaa tctatgtcaa
     8821 atataaacaa gtttataaaa aacttagatg aaaatatatc tatcattgct aaacaagaag
     8881 gaaaatcttt tacacttaaa agtcagataa ataatgtaaa tctattgttt gatgaaaata
     8941 tcattcttag agtcgtcgaa aatataatat cgaatgcttt tagatatgct agaaataatg
     9001 tatccatact tatatatatt gaacaagaac ttcttacctt tgtaattgaa gatgatggta
     9061 taggatttag caaagaatct ctaaaatcag ctttaagacc tttttataga gataagactt
     9121 taaatgaaag caatgcacac tttggtatgg gtctttatat ttcaaaaata ttatgtgaaa
     9181 aacatggtgg ctctatttct attgaaaata atttgactaa cagtgctaaa attactgcta
     9241 aattctcaac aaaaaattaa agcaatatta aatcaatttt ttaggctttc actcctcttt
     9301 tataaacttt ataacttaga gtttacaaag tgtttttttg aaataaattt ttagtaaaca
     9361 aaattaaaaa gttgagaaaa aattgagttt taaaacttac actcttctta tatagaaaag
     9421 gagagtgttt tttatgatta taaaagcaaa acaattatca aaaatatatg gttctaataa
     9481 caataaagtt atcgcactta ataatgtaaa tttagaaata aactcaggtg aatttgtttc
     9541 tataattgga ccttctggaa gtggaaaaag cacactttta catattttaa gtggattaga
     9601 taatcctacc tctggacaag tgttacttga tgataaagat atatataaac acagtgaaaa
     9661 agaactatct gcacttagaa gaaaatcctt tggattcgtt tttcaacagt ttaatctttt
     9721 acctgttctt acagcatctg aaaatatttc aatgcctgta cttctagata aaaaacaacc
     9781 tgataaagac tatttaaatg aaatttcatc attacttgga attgcagata gactcaatca
     9841 tcttccccat gaactttcag gtggtcagca acaaagagtt gcaattgcta gagcacttat
     9901 tgcaaaacca gatataatat ttgctgatga gcctacagga aacttggata gtaaaagtgg
     9961 cagtgaagtt atgaatcttc ttataaaaac ttcaaaacag tttggaaaga ctttagtggt
    10021 aattactcat gatgatagaa ttgcaaaact tgctgataga aaaatttcaa ttattgatgg
    10081 tgttcttatg gaggtgaaat agaaatgaag aattaccttt cactttcaat aaaagaatta
    10141 aaaagccaga aacttatgac tacattcatc attatagcaa tagtactatc aactattatg
    10201 acaactgtgg ttggacagtc aattggtatc ctacaaaatt taagaattga acaagcccgt
    10261 tcttttaatg gtgatagaca tgtatccttt caccaactca ctaaaaatca agttgatgac
    10321 ataaagaaag atgatagagt ttatcaagct ggtacttcaa taactcttgg cagtagtaaa
    10381 ataaaggatt ctggtatctc tgtacttgta aaagagtatg ataaaacagg actttctaac
    10441 taccccaaat taatgaaatt aaaatctgga catttgccta aagataaaaa cgaaatagcc
    10501 ttagatgaaa acacactaaa gcttataggt ataaaaccaa gactaggagt gactatacct
    10561 atgaatttag atatttcact tttaaatgat acaataccac catataatta cacagctaac
    10621 tttaaattga gtggtatttt ggaggatgat tatacaggat acgtaagtgg tatagtaaac
    10681 ggtattgtgg gcaaaggtgc atcagaaaat ctattaccta agagatatat tttatcctct
    10741 ttggatttta aaataaaaca gcaagagaag tttcaagaaa tagtaaatca attagctaaa
    10801 aaaataaatc tttctcacaa ttcaattcaa tataattgga tttacttaaa tgctctcaaa
    10861 atacagtttg aaaaagatga aaatagttct aatagtgatg gtatatctat gattatattg
    10921 gtatctttat ttgttgcctt attggtttta ctggcttctg gacttgtaat ctacaatatt
    10981 ttaaaaatct ctgttacaaa gaaaattaaa gagtatggat gtttaagagg aataggagct
    11041 gaaccaaacc agatatataa gatagttatt ttacaaatct taattttatg tactattgcc
    11101 atacctattg gagctgtaat tggaattata tcttctaaag gcataactgg aatggtcact
    11161 aatatcttaa atccagatat acttctagca aatgataata aagaaattac tgagcttata
    11221 cataaaaaca caacagcata tatgttccca ttagtattaa gcactagtat atctttgatt
    11281 ttttcattta tttcagcatt accatcagca atatatgctt cacatgtctc tcccaaaatt
    11341 gctatggctg gcagtactac caaaatcaaa agaaaaatta aacgagaaaa aacaataaaa
    11401 aactttgaaa gacatctagc atggctaaac ttaaaaagaa ataaaggaag aactataata
    11461 accatactat cattatttat gagtataaca gtattcgttg cactgagtga gttctctaat
    11521 gtattagatg tatctaggtc agtaagtaat ttaaaagaag gagatttttc cttaacaaat
    11581 gaaatatctg gttttgataa gtcaatacta gataaaatag ataacatgaa aaacgtcaat
    11641 cgcacttctt ttataaagta ctctgaatac aaacagggcg aaatagatac agatataaat
    11701 tttgaaaata gtggtgagat gttaaaaatc attggaattg atgaacaaac tttaaaagac
    11761 ttaatgcctt ctattacaga ttctacatta gaagacttta aaaatggttc tatctgtttt
    11821 ataaaaaatc cacttgctat ttctacacca ggtgtaaaaa ctaaatatac aaatttaaaa
    11881 cctaaagata atatcacaat taacaaaaaa caactagata tatatagtac ggtagataaa
    11941 atgttctttt tacaaggtaa tggctgggta aatggtgttg atattattgt atatgattct
    12001 gtttataaca ccttgacaaa taaaaacaag ttcaaccaga taaatattta tgctaaagat
    12061 aaatcagatt tagaacaaat aagattgtct attgaacaga tttgtgaaaa taatcctggc
    12121 tctcattgga tatcatatat tgaatcagat aagcaactta aagagagttt taaacaaata
    12181 gaacttctag catgggcagt tatattattt gtgggattga ttggtacttt aaacatcatt
    12241 aacacaactc atacaaatat aaatactagg actaatgaga ttggagttaa aagagctatt
    12301 ggtatgagta atagtagctt atataagatg tttttatggg aaggtgttta ttatggaatt
    12361 tttgctgcta tacttggttc aattgctggg tatgctagtg ctattattat aaacatggca
    12421 actatagaaa agcttgattt tactaatata ccaattactt caattttaca agctactatt
    12481 atttctatac ttgcatgtat tatagctact cttattccat taagaaaagt taaaaaaatg
    12541 aatataattg actgtataga tatcaattta taactatttt acagataata atataaatca
    12601 gattatcaat gactgtctcc attttctttc aaatctaact aataaacctt tccaactata
    12661 atataagttt taaaaaaagg cctgtctcaa aatagagata aacctttttt cattgttgga
    12721 atgatgaaaa tatatttaac ttcacaaaaa aagagtgcct cacgaactaa aaatttcgtt
    12781 ctgagacact cccctttaat ttaaaatata tagttaaatg ctatgccaaa atttcacaca
    12841 tgctccacct gattttgaat tttctatttt aacagaccct ccaagctgtt ccactaattg
    12901 tttgacaatg taaagcccaa gaccagaatg cccaccttta gtctgtctag cttcatctcc
    12961 tcgataaaat ttatcaagag ccttttttaa atctttagag ctaaacccac tgccagaatc
    13021 acaaatctca taagaaatac aatttttttc agcctttgca ataatactaa tattaccacc
    13081 tgacggagtg tattgcagac tgttagatat gatattatca aaaattcgtg tcaatctatc
    13141 taagtctatt tgaattggtg attgtatatt accatacatt ttcaatataa gttcaacgtc
    13201 cttttgatga gcctgtaatt catagtcttg taccttttgc accaaaaatt caggtaaatt
    13261 tataggaaca ggatttaatt gtatatttga cttttctaaa tcagacgtat attgcatctt
    13321 ttggacaaga gcagcacttt tttccgtatt ttctcttatc actgtaagat acctatgaag
    13381 tttttcattg tcatctgtat tattaccaat aagtgcatcc gtatatccca aaacaataga
    13441 aagaggagat tttaaatcat gtgctagagc ttccaccatt tcaacacgtt cctgctccat
    13501 cttccactgt gcagataaag agttttttaa ttcgtctttc atttcagaaa aggcactaca
    13561 aagtttaccg agttcattat ctgaataata gtcgatttca aaatcaaggt ctttttcttt
    13621 tatcttcttg gatgcatcaa tcaatagatg taatggttga ttgatattct ttacaaactg
    13681 cttagaaagc catatagtaa aacctataac atatagaaat ggagaaaaca tagctattac
    13741 aataactgca aacgtcaacc tccccatact atttgcaaag gtcattttca cttggtagaa
    13801 tagaataaca gctccctcaa tttttccatt agtaccttta attggaacag tataaatata
    13861 accaccttta cgaacagttg tatttataaa attattaaat aattcttctt ttgttttaaa
    13921 tggtttttta gggttattac catatagaat attgccatta tcatccacaa cttgatataa
    13981 cataccatcc ccgcgaatag ttctttttaa accttcttca tttgattgtg ataacaaagc
    14041 tatgtttttt tcatcaatgt attttttaat tctaggaact tgtcgctcat aatagtttgg
    14101 tggataaata tccttattca aggaataaat aaacaaataa aaagcaaata cataagtaat
    14161 cactgtggca actatactag ctattataat aaaaataaaa gtacgcctga attgggtggc
    14221 aagtgattga tttttcattt aatgacctct ctccctttac attttattcc acttataccc
    14281 aatcccccaa actgtggaaa tgtattcttt ttctggtgtc acagcagaaa acttagctcg
    14341 tatttttttg actcgttcaa caacagttga tgaatcacct tcagaatcac acccccatac
    14401 tttttcatag atttgttctc ttgagaaaac ttgtcctgca tggagtgcta gtaattcaac
    14461 aatatcatac tctatttttg ttaaatcaat atccttacca tcaattttaa ttgcacgttc
    14521 cttcatatat aagcataact tttcaaaata caaagtagac ctcttgttct cctcattgat
    14581 atactgtgaa cgcttttccc tacgcagatt agcttcaatc cttgccataa gttcacgcaa
    14641 tccaaatggc tttgttacat aatcatcccc tccaaaggtc aaccctttga ttttgtcggt
    14701 ttctgattgt tttgcactta agaatataat tgggcacaaa acatcatctc taattgcctg
    14761 gcatacctca aacccatcca ttttaggcat cataatatcc agtataatga ggtcaggctc
    14821 attttttgat agttctatac ctgcctgacc atcataagct attagcactt catgcccttt
    14881 tgccttcaat tcgtcctcaa gtagcattac taaatctatt tcatcatcaa taatcaatat
    14941 tttactcaat ataacaccac ctttctctta tgggaaggtt agtattaaaa caatattcgt
    15001 ctattcgtaa cttttccttc cctcccatat tttaaaccaa ataacgcctc ctatcaagaa
    15061 tataatcaaa cctattgcta ctactataaa tactacagta gctgattgca tcattttaga
    15121 gtaaaatacc tcagttgaaa tagttccagc ttctttaata aaataagtac ctggaagcat
    15181 acctagtttt actggccatg tccagggaac aaatgcccag acttttgcac caacgctagt
    15241 taatccaagt attgctgcca tcaaaattcc accaatacta ataccaatag acgcacccat
    15301 accccatgca aaactcaccc aaagatgaat agctaatagt ggaagagtcc caatcaccac
    15361 aagtcctgct gctgacagga ataaccatat tgttgctcca gatggcactg caatattcat
    15421 tcctatgcag agtatcaacg tagcaataaa tgtgcatata gttaggcaaa acagaagaaa
    15481 aagaaatttt cccagatata atctaacacg agaaatacct acacataaaa aaccattaaa
    15541 atttccagca agctcttcct cctgcactat aaatcctgct aaaataccta ctccaatagg
    15601 aatgatgaat acagtccata ttgtaaaaaa tccttcaaaa gcaaattctt gtgtacttcc
    15661 agatttaatt gtgagataag caaccacaca taatgaaaaa ataataggca tataaagagt
    15721 aagaccttgg actgccgtcc tctttgctct aagccattct gatgataata gttttatcat
    15781 ttgtcatccc tcctattgaa ccaagctgca gtaagtgctg ttaatactat aaacacaacc
    15841 aaagaaacaa caatcccaat aggaatcact gaagtattca aaagtgggtc tccagcttct
    15901 aatatagtac cattaggatg tatgttgatg attgggcata ccattctaac tgcccaactc
    15961 caaggtactg caacccaaaa tggttttgac gcagcaagga caccaaatat catgcctaaa
    16021 gctccaactc ccatacttag gaacatacct ttccatgtag ctagccatag ctggattgga
    16081 agtatagcaa gagaaccaac ccaacataca atacttgccc ctataatctg tccaaaagga
    16141 attggtccag ctttcaatat taaaccagtc ataattgtta cgactattaa aactagcgtt
    16201 gaaataaaac tgtaaactgc catagctata attttattaa tccaaattgt catgggagac
    16261 acattgtgtg tacgtaaagc acgataattt ccagcttttt tttcctggga agctaccaaa
    16321 gtagcaaaca atgcaaatcc aatagacaga aacatcattg accaccagtt aaaaatcaat
    16381 gctaaaagac tttcccatgc ccaagaattt atttgagata gtggattttg cataagtgtt
    16441 gattgcatta taaatgcata tgctgcaaaa gatactggga aaaaaacaat aagtttaccc
    16501 ataaaggttc ttttatactt tagaagttct gattgtaaag cattcatctg ttttgtcctc
    16561 ctttaagaat aacatctgta aaaaattctt ctagattttc attagggtca ggcattcctt
    16621 gaaatagtag tcttcctcca tttataattc ctatattatc tacaacttga gcaacctctg
    16681 atagaatatg gctagaaaga attacagtta tacctttttc tggaaaagaa gcaatcaatt
    16741 cacgcaattc ttgaatgcca aaggggtcaa gaccattagt tggctcatct agtattaaca
    16801 actctgggtc attcaaaagt gcaatagcaa ttcctaacct ttgtttcata cccatagaaa
    16861 attgtgaagc tctcttttta cctgtatttt tcaaatttac tatttccaac acctcataaa
    16921 ttttatcttt aggtattccc aatatttttg tatgtactaa caaattttcc tctgctgtaa
    16981 ggtttccata caatgcagga gattctatta aagaacctat tttttcaaga gattctcgtt
    17041 tccaaggctt tctatcaaaa ataatacgtc catctgttgg gcgaagaaga ccaacaagca
    17101 ttttaagtgt tgtggacttt cctgcaccat ttggtcctaa aagtccatat atactatttc
    17161 gttcaatttg tagagaaaca ttgttaactg ccatttgttc tccatatctt tttgataagt
    17221 tttttgtttc aataattaaa tctttcatat ttatttctcc cttcttgtaa tactttaaat
    17281 ctattactaa gagaatacta acatgaaaaa ataacaattc tataacacct aataatttta
    17341 ataaaaatta aaataaaaaa tagagttacc aattttattt tggcaactct atttaagttt
    17401 atgttttaca gttatattag atttaagctt agtttcatta tcacactaac ttcaaattta
    17461 ctctataatc cttaaatcaa gcactaattt attaatcaaa cactaatcta ttaatttata
    17521 tttctttaga catctaatat agtctgctac taaacaataa ttatttatat catatttatc
    17581 taatccttta aaagcagtta tttcatcatt atttttcata tacatatttc cactgctcac
    17641 ttttttcttg tgatacttct tgagtaagtg tacttatttt ttcttgagat attttttcaa
    17701 ttaaactctc ctttcaatac ttaaatatcc ttctgaacct ccatgactaa agtcacaagg
    17761 ttcctaattc atagaatttt gcatactaaa atatgtctta ctaattctcc acaggatatc
    17821 ccccatagtt cctatggttc ttacataagt tatctatttt aaattgttat tagttagatt
    17881 ctaaaaatta tttgttttat cactaatata atactcataa aaactttaca aatcaattta
    17941 aatttgctac cttttattta taacaactta tagtacattt ctcctatgct tttcaatata
    18001 ttacttttaa aaggaggttt tccttatgat tttaaataga actgagcttt tccgaggata
    18061 ttctttagat agatttaacg agatatgcaa tatattatca gtaaataaaa ttaaatataa
    18121 gtataaagtg aaaaataata cttactctaa aaaacctttt tataatgaaa taacccttgg
    18181 caatttaggt caaaaagaag atttctctta tgagtactta atttatgttc ataaagacga
    18241 ttatgaacag gcagaagctc taataaattc taagttgcga tagattattg ataaaacatg
    18301 acattctgtt gtcatgtttt atatgttatt atactttcaa atatgttact atattttcaa
    18361 aattatatac cttaaaacta tacttttata gtaatttaaa gcttaaaact aaggagactc
    18421 gttatatgaa aataaatata aaatcaacat taaatgaatt tattaaacag aataatcttt
    18481 ttgatgacaa cagaataata tcctaccttc ctaatataac aatagacaca gacaaaataa
    18541 aaactataat gattaatgaa gttgtcccaa ctaacaccaa tgacgatttt tatagtatag
    18601 ataaagatgc tgattattta aaaactacta ttcctttatt taacaatgca ggaatagaag
    18661 tatctaatat aaatgatatc ctagatatgg gtatctatat aactaatgcc gtaaaacttc
    18721 ctaaatcaga atatacaata actcgtgata caattaaatt acatatgcct attttagaag
    18781 aagaaattaa attgtttaaa aacctagagg tagtaatgtt aatgggagat gttgcaaaga
    18841 aatcttttaa tatgattact aaaaaacata taaaaaagaa tgtcatccct tccatttcaa
    18901 catataaact tcgtaataat gaactttatt atgataattt aagagtattt ccatcatata
    18961 ttatgactgg tggaaacata ctgattgaaa aatcaaaatt tgaaatggca tcagaagata
    19021 taaaaaaaat gttcgagatt ataaacggtt gagattgcaa aataataaaa actaatttag
    19081 acaaataata agtgcctcaa aaaattctat ttataaggca cttttatttt atattagtgt
    19141 aactatatgc tattaatata actatatact attaacataa ttctaaaaat atatctttca
    19201 cactcattac cccactttgg ctttttatca actatatttt tagctatcaa tataaacctt
    19261 ttatttagtt taaagctata cttgcacagc ttaaataaaa attttattta actatatacg
    19321 tttatttaat caactataaa tgaattattt ttaacaattg acaaactaaa ttaatgataa
    19381 tatactttat gtattacaaa tgtaagtaga aggaggtata gtatgaaaaa gttaccacat
    19441 atttcagaag cagaatatca agttatgaaa attatttgga aatatgctcc tatcagcact
    19501 actgaagtaa ttgaaaagct ggtagaaaca agtacatgga gtcctaaaac aattcaaaca
    19561 atgttattga gattagttaa aaaaggagct ttaacatatg aaaaaaatag cagagtattc
    19621 gtttatactc cacttgttaa agaagaagaa tacgtagcta cagaaagtag ttctttttta
    19681 aatcgttttt ataatggcac tcttaattct atggtactaa actttttaga aaatgataaa
    19741 ctatctgaag atgatattga ggaactgaga gaaatcttaa ataaaaggac gactaagggg
    19801 gataaataaa tatgtatgcc ccattcttta tacgattttt actcagtaca ttaaccttat
    19861 caatattaat tgttgtaatt ttacttgcca aaaaagtatt taaaaaacat atttctgcaa
    19921 agtaccaata caatattgga tttatattgc ttataatgtt aataattcca tttgtccctc
    19981 ttaaatatat taatcttgga aatgtattta actatttata tacttttaat caacttggaa
    20041 gcaatactaa taggacttct atgataaaaa atagtccaaa ttctataatt aacaattcaa
    20101 atgcattaaa cgatttttca gtatccctaa accaagttaa ttttgatatt ttaaatattt
    20161 tattgctaat attatggata attggaattt taatcatgat agttattact attcattgca
    20221 acattaaaat aaaaagtatg aaaaaatcaa tacaaatttt aagagatgag gagatagttt
    20281 ttatatttga aaagtgtaaa aaagatattg gtataaataa ggattttata ctatgcaaat
    20341 cacctattat aaatacgcct attacatttg gatactttaa accacacatt atattaccag
    20401 ataagtctat atctaaatta tctttaaaag atataaaata tatcttactt catgaattgc
    20461 aacattttaa aaatagagat atgctgataa attatataat gtgctttttt caaatattat
    20521 attggtttaa tcctcttgta tggtatgcat ttaaagaaat gcgtatagac cgtgaaattg
    20581 catgtgatat ttcagtttta aaaaagcttg ataaagataa tcatatagaa tatggacaaa
    20641 ctctaataaa ctttgtagat aatatttcaa gaccatcaaa tcttacactt acatcagata
    20701 ttggtgggtc aaaaaaacaa ataaaaaaac gactattgaa gataatggat tttcataatg
    20761 aatcaaatac tttaaaattc aaaagcattt taatttttac attgatagct ttaattgtat
    20821 ttggaaatat tcctaaacta tctattatgg cagatatcaa cgaaaaatat agacctacaa
    20881 ataaacaaac tatgtatgag gatttaagta agtattttaa aggttttgat ggaagttttg
    20941 ttatgtatga tttaaaatcc aagcaatatc atatttacaa taaagaaaaa agtaaaacaa
    21001 gaatttctcc aaattctacc tataagattt atagtgcatt attgggattg gaaaatggga
    21061 taataacaag agataattca catatacctt gggatggaaa acatcattct aatatttctt
    21121 ggaatgaaga ccaagattta ttttctgcta tggaaaattc cgtaaactgg tactttcaga
    21181 ctctagataa aaaaacaggc ataaaaaaca tacaaactta tcttgagcaa attggatatg
    21241 gtaattatga tgtttcaggt ggtatctcaa acttttggct agaatcttca ttaaaaatat
    21301 cacctattga acaggtagaa ttacttgaaa gtttttatac aaataagttt aattttgaag
    21361 ataaaaatat agaaactgta aaagattcat tgttaatatc aaaaaaagat ggggtatcac
    21421 tttctggtaa aacaggtact gctaatataa atggaaaaga tgtgaatggt tggtttatag
    21481 gctatgtaga aaaaaatgaa aatacctatt tctttgctac aaatattcaa agcaaagatt
    21541 attctaatgg tatttcagca tctaagataa cattatctat attaaatgac aaaaaaatct
    21601 ataatcccta atatatttac tatacattct aaaaaattca cataattttc atattaatta
    21661 tctattaaat tcatatacaa ggcttattat ataaacataa aagatagt
//
LOCUS       DBGJFK010000067        21495 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.067, whole genome shotgun sequence.
ACCESSION   DBGJFK010000067 DBGJFK010000000
VERSION     DBGJFK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21495
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.067"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            154..597
                     /locus_tag="ACOIAP_002803"
     CDS             154..597
                     /locus_tag="ACOIAP_002803"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639682.1"
                     /translation="MIEIKTIEINKKGQIDLLMLADPCEEMIDKYLNKGTMYALYDNE
                     ELICIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMIVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            769..939
                     /locus_tag="ACOIAP_002804"
     CDS             769..939
                     /locus_tag="ACOIAP_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639683.1"
                     /translation="MDSNNDTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            1312..2409
                     /locus_tag="ACOIAP_002805"
     CDS             1312..2409
                     /locus_tag="ACOIAP_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HGZ2639684.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTVIEEKDREWTKKLNDILSRDDFS
                     NEKLDKIKNLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKPFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEESNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILSHVKYNHIEDYVNCLRLT
                     IDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RVLDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGVEKGIAKGKREERFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKIYNQN"
     gene            2589..3077
                     /locus_tag="ACOIAP_002806"
     CDS             2589..3077
                     /locus_tag="ACOIAP_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HGZ2639685.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLYNVKLIKEFV
                     AK"
     gene            3163..3570
                     /locus_tag="ACOIAP_002807"
     CDS             3163..3570
                     /locus_tag="ACOIAP_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639686.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKLLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            3571..3789
                     /locus_tag="ACOIAP_002808"
     CDS             3571..3789
                     /locus_tag="ACOIAP_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2639687.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENDI"
     gene            4514..4819
                     /locus_tag="ACOIAP_002809"
     CDS             4514..4819
                     /locus_tag="ACOIAP_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639688.1"
                     /translation="MPSMIMEIVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     IGIIAAGIALIFFRNGIDSIGSIATYGIFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            5515..6108
                     /locus_tag="ACOIAP_002810"
     CDS             5515..6108
                     /locus_tag="ACOIAP_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2639689.1"
                     /translation="MNYTIEPTQLNKMYKDKAVINNINIHVRKEVIYGFVVQNRAGKS
                     TVMKMLLNLTKSNSGEIIIFGKKLEETDFEMLKKISTIIENTYFYENLTDKQNLDLHC
                     EYMGYYNKEHISEILKCVGLSKQSSKKVSKYFLGIKQCLLIARAILTKPELLILDESI
                     NALDPEGIREMRELFNKLNTDYITTIFTSSHILSEVE"
     gene            7236..7886
                     /locus_tag="ACOIAP_002811"
     CDS             7236..7886
                     /locus_tag="ACOIAP_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2639690.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEKEDV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            8198..10243
                     /locus_tag="ACOIAP_002812"
     CDS             8198..10243
                     /locus_tag="ACOIAP_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HGZ2639691.1"
                     /translation="MKKITKERIENTMKKLFTSETFLEYQFISDCQISPDGGYTAFIV
                     KKADIKENAYTSQVYILNNKSGELKQITSINSVGAYAWEDENTILFPALRNEKVKEAV
                     KDGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRPIVEGLSE
                     EEQQKKINAYNNRHYEHFKEIPYAVNGEGYVSRKRKRLYLYDSNINELKAITAPMFNV
                     VGMKISDGKILYVGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIVKGFELYQNQV
                     ILNLTDALSYGNGENGDFYTIDIDTKEMKLLSEHQHHCIGNTVTSDVKMGVGQTTKVD
                     GEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVAFLGDRLPEV
                     YTVENGTLCKKTHLNDHILEEYKISEPEYIESKGSSKWEIQGYVYKPVDYEVGKKYPA
                     VLVIHGGPRLTYGPYFMHEMQVFASAGYFVFFCNPRGSEGRGNAFADIRKQFGDIDYI
                     DFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRSIANWSGM
                     EGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDYRCYMQEA
                     FQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIKKDNIGQ"
     gene            10262..12217
                     /locus_tag="ACOIAP_002813"
     CDS             10262..12217
                     /locus_tag="ACOIAP_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HGZ2639692.1"
                     /translation="MEKIKIENSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGIDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENTTKAITPKFCEVAGIDVSSDKKRILYVGQIYEDCATPFS
                     GLWEYHIESGETKELVPQGKYQISLAKYIGENKVMLQASTLDRSITQNHDIFILDLST
                     SEISMIASLDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFDEFDTNTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFIAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDICIEKYPGIDAERLGVA
                     GGSYGGYMTNWIIGHTDRFKAAASQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIVRVNAIVDWFERYL"
     gene            12233..13423
                     /locus_tag="ACOIAP_002814"
     CDS             12233..13423
                     /locus_tag="ACOIAP_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGZ2639693.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTSAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAESTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVLVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            13874..14248
                     /locus_tag="ACOIAP_002815"
     CDS             13874..14248
                     /locus_tag="ACOIAP_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2639694.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAS
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            14250..15107
                     /locus_tag="ACOIAP_002816"
     CDS             14250..15107
                     /locus_tag="ACOIAP_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639695.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVIKRDSGKIKIFGKDFNGNEKELKNRIGVVFDDSYFYDELSMAEMKSIIAP
                     SYDNWCEEDYQKNMKHFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     EEHRKVKGDIKFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            15110..15748
                     /locus_tag="ACOIAP_002817"
     CDS             15110..15748
                     /locus_tag="ACOIAP_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HGZ2639696.1"
                     /translation="MLIHLVKKDVLIVKKYVLFILFLAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFIMVFIYCTLVY
                     WIENLLIPQMGTFDLTYILIVLLISSIIYGVYMPVQYKLGYETTKAFFVVIIMASSFV
                     LPLIIGHSNFEVPFIYQYSSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            16704..17438
                     /locus_tag="ACOIAP_002818"
     CDS             16704..17438
                     /locus_tag="ACOIAP_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2639697.1"
                     /translation="MNLTKGLDVLKISSNVFGEDKVMYIPVIYTEDEATLIDTGLPGQ
                     GDLIVDALNKSNTSFDKLKNIIITHHDIDHIGNVNYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIGDKMLSMLNVMGLGFKSSYTKVDVSLDNHEFLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQIDNGELKPVDVMHSNKQELKDAIKNISNYD
                     IEAIVFSHGGLYQENIIETLNNIIIE"
     regulatory      18127..18203
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            18554..19726
                     /locus_tag="ACOIAP_002819"
     CDS             18554..19726
                     /locus_tag="ACOIAP_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGZ2639698.1"
                     /translation="MLGIIGIPIGAIIGLIDTVFGTVLLKITDIRETYPMYLIPFLSV
                     VGVVIAYCYFKFGGKSSKGMNLIFEVGHGEEEIIPLRLIPFIISGTWLTHLFGGSAGR
                     EGVAVQIGATFSHWIGKRLPIKNASSIFLVTGMAAGFAGLFGTPIAAILFAMEVLVAG
                     SLEYQSLFPAFIASFTASEVTKALGLEKFSFALSSKVVFDLSIFWKFIALGIIFGMVG
                     GAFAWCLKLSKRKICNRLKNPMIRIAIIGACISILFLLFDKGRYSGLGTNLIQNSFYG
                     GEIYSFDWLLKFVLTILTLSAGFQGGEVTPLFSIGASLGVLLAGFFNLPIELVAALGY
                     ASVFGSATNTFFAPVFIGAEVFGYSYLPYFFVVCAISYVFNMDKSIYSLQKISTKQ"
     gene            19950..20150
                     /locus_tag="ACOIAP_002820"
     CDS             19950..20150
                     /locus_tag="ACOIAP_002820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639699.1"
                     /translation="MMGYIPKAKVQIAIGSVPLAMEMVSGQFILTLAVLSILITVPLG
                     TFGIDTTYKKLLTSVKGDSKQK"
     gene            20341..20721
                     /locus_tag="ACOIAP_002821"
     CDS             20341..20721
                     /locus_tag="ACOIAP_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2639700.1"
                     /translation="MYLKKLSKLELVIMKFIWNLDIKTNSCEIIDYMKEEHNLSEKVA
                     LKTLSKLSKKRFLYVQETDKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEDLTEEKIKSLENWVVNWEEACI"
BASE COUNT         8274 a         2215 c         3588 g         7418 t
ORIGIN      
        1 tagtgctgat attataattt attattagta ttaatattct agggaattat cactatattt
       61 taaaaaagta aaaatatata tcaaaatgaa ttaaataagt actgtaagaa gtttgctaaa
      121 ttaaggtttg aataaagtga gggtggagaa cttatgatag aaataaaaac tatagaaata
      181 aataaaaaag gtcaaattga ccttttaatg ttagccgacc catgtgagga aatgattgat
      241 aaatatctta ataaaggaac tatgtacgca ttgtatgata atgaagaact tatttgtata
      301 gcagttgtaa atgaaatttc caaagaaata tgtgaattaa aaaacattgc tacatatgag
      361 cattttcaaa atatgggtta tgcctcaaag atgatttatc atcttttaga tgtttatagt
      421 aaaaaatatt catcaatgat tgttggtaca tctgaaagcg gagttccttt ttatgagaag
      481 tttggatttg tttattcaca taaaattaaa aacttttttg tagataatta tccagaacca
      541 atctttgagg gagaattaca atgtgttgac atgttgtatc tatcatataa cttttagata
      601 ggataatatt tttaggttaa tataaataat ttattcatat aattattgga actataattt
      661 ataaattatg tataataaga gtataattta tttagaagct gttatattgt attagattca
      721 aataatatat ataataactt gtttattttg aattttggag gattaattat ggattcaaat
      781 aatgatacta taaaatcaac tgttaaaaag ggtatttctt ttggttcttg tttagcaatg
      841 attatttctt atactgcatg gaaatctatt ccatgggcta tttttcatgg cttaatgagt
      901 tggatatatg tactttatta ttgggttaag tatgcataga ttaaattaat aaataagtgt
      961 gtaatattgt gaagtttaag aaacaaaatg taagggagtg tctcgaagtg aacttttagt
     1021 ttataaggca ctcttttttg tattaaataa actatatttt cattacttaa acaatgaaaa
     1081 agattattat ctctatttta atacatacct ttatattcat tcatttatca acaatagttt
     1141 taaaaagaaa gttatctaaa atctattgta atctaagtga ttctctttaa agtcttaact
     1201 ttagtaatga tatatgagtt tatcatgttc ttatttcaat aatgcaaatt ttacttagaa
     1261 gtgcagactt tggtatgaag aaatgggtaa taataaaaaa gaggtgttga tatgaaagaa
     1321 aaattagaag aaaaatctaa gattattaaa acatcaaaag agtataagag aactgtaatt
     1381 gaagaaaagg acagagaatg gactaaaaaa ttaaatgaca tacttagtag agatgatttt
     1441 tctaatgaaa aattagataa aatcaagaat ttaattccaa aagaaatatt gactagtgaa
     1501 aatgttggag aagttgtaac tgaagatggg tatgctaagc ctgagtatga tgaggtattt
     1561 aaatcattat ttactttaaa taatgattac gatttacttg caaattttat aaatgatatt
     1621 ctcaaagatg ctccatatgc taataggaat atcaaaccgt tcactcaaat aaaaagaata
     1681 attaaggttg aaaccgaccc aacaattaat tacattggtg agaaaagacc tagacttgat
     1741 attttggctg aagatgaaga aagtaatcat ataaatattg agatgcaaag agctcttgaa
     1801 gaggattatt tggaaagagc tgaatattat cttagtcgtg tacatggtag aaagttagaa
     1861 gaaggtaaag aatataaaga aattggaaaa actgttggaa tacatatact aagtcatgta
     1921 aaatataatc atatagaaga ttatgtaaat tgcctgagat taacgataga tgggcatcca
     1981 gatattttct ctagtaaaac tgcattatat tttatagaac ttccaaaaat tcgtaaatcc
     2041 agttgtatag caaatagagt tctaatatgg ggtaaactta ttgataatcc ttctcatatc
     2101 gatattagaa tactatctaa aacggattat gttattaaaa gagtacttga tagattaaaa
     2161 gaattaggca gtaatgagga ctatttatta aatttaaaga gaggtgcgta tattatgaat
     2221 aaaagtagaa attttaaaga agaaattttt caagaaggtg ttgaaaaagg tattgcaaaa
     2281 gggaaaagag aagagagatt taatatcatc ataaaattaa aaaataaagg atacaatttg
     2341 agtgaaatat gcgatattat agatgatttg aataaatcag aggttgaaaa aatctataat
     2401 caaaactaat actataattg agatggcact agataaatac aaagcttcct cttttaaatt
     2461 taaattaata taaaaccttg ttatttaact atagtagata caaagagata tataagctaa
     2521 ggagatgatt taaaataaaa gtttgaacca tctccttctt atagaaaaac aaagggattg
     2581 atttatatat gaaattttat actatacaga ctttagaatt ttggaacaac aataaaaaca
     2641 ataaatatct atcaaatgat tattctttta tattagaaga ctttgatatt ccatacaaat
     2701 ggatgtatag tcaaatgaca aatagaatat atgaatttga tgatagtatg atatgggttt
     2761 ggacgaagag acctgattta agatgtagtg gttatttaga aaaaggaaaa aaaggtgttt
     2821 tacttgaaat agaaataagt gaagataatg tgttattatc agaatttgat ttatggcatt
     2881 tacctttaat ggatattact gtagagcttt atgaagatga acaaattgaa aagaaggtaa
     2941 gttgggaaag aatatttgac ttagaactgt gttcaaaatt aaatgaagtt aatatagaag
     3001 atttgacatt gcaaggagtg acatctaaag ttcctctata taatgtaaaa ttaataaaag
     3061 aatttgttgc aaaataatat ttttattgaa atttattcaa aaaagttata tatttataac
     3121 aagaggtgtt ataaatatat aactttttaa gggggatttt atatgtctaa acaacaaact
     3181 ggtattaaat caacacttat ttcagaaata ttgggaattt cttattgtat tggagctaca
     3241 ttagtaaata agtatttttt taaaggaagt agtattgaat atcttcctat aattatttgg
     3301 gtattagcta tgggagctca gtgggtctat aataaaaagt atgatgattt aattgatgag
     3361 gcatcaaaat gtatactatc aagagttaat gatattgcaa taaaattatt gtttttttct
     3421 gtagctatag tatctatatt tcttgtaact ttggacataa atgtgtcaaa tttaaatata
     3481 ggaatgtctt tattagtcat tttgtttatt caatccttgt tgaagttaat tttatttata
     3541 tattttgaca gaaaggggat atacaattag gtgtcagtat tactaaagac aaaaattaaa
     3601 tcctatagag aaaagaacct tatgacacaa ggtgaacttg caaagtcagt aggagtaaga
     3661 cgtgaaacta ttgtacattt agaaaatggt cgctacaatc cttctttaaa actggcaatg
     3721 gatattgcta aggtatttga tacaactgta gaagagttat ttgaatttat tgaagaaaat
     3781 gatatttaaa tttcatgtat tgcttatgca ttagagaatg aattaataga taaaaaattc
     3841 aagtttatgt attagagaat gaattaatta taggtaaaaa accaagctta taaattagag
     3901 aataaatgat taatagatga aaaaccaagc taatggatta aagaatgaat gatttataga
     3961 tgaagaagca accttataga ttagagaata aataacttat aaataaaaac caagcttata
     4021 gattaaaaaa tgaatgattt atagatgaaa aatcaagctc atagattaaa aaataaatga
     4081 cttatagatg aaaaaccaag ctcatagatt aaaaaatgaa tgacttatag atgaaaaacc
     4141 aagctcatag attaaaaaat aaatgactta tagatgaaaa atcaagctca tagattaaag
     4201 aataaatgac ttatagatga aaaaccaagc ttatagataa taagtccatg cttataagca
     4261 gaaaatgaat agtttaatag attaaaaaat atatatttgt gaattataga atgaatagct
     4321 ccataaacta gaaaatttat aataatatct atatgaaaat tagaaatatt ttatcacaaa
     4381 aaaattaagt taaataaata tgaaattact tccaaatata cttccaaaaa catctaatcg
     4441 catatataat ataattataa aaataataaa tatttttata gtagtagtta attattaata
     4501 aggagtgttc aaaatgccta gtatgattat ggaaattgta ggagtactat ttatagctat
     4561 tggattaatc ttgacattca ttgaaataaa aggaaatttc ccttcttttt atggttttgg
     4621 tcaaaattct atagggaaaa atgctatagg tattatagca gcaggaattg ctttaatttt
     4681 ctttagaaat ggcatagata gcataggttc tatagctact tatggtatat ttttagctat
     4741 agaacttgtt gtaatagttg catatttctt aataagaaaa aaatttacta aagaagataa
     4801 acatttaaga actaattaac taaattatct actataaaat tggaaaatta aaaacaaata
     4861 aaagtttgtt tttaattatt taaaatccaa atttgattat ttttgaagaa actatgttct
     4921 gtataaaact gggatgtggt ttctttttta tgtataaaat aattttttag taaaagttaa
     4981 aaagtatttt aaaagataga tggtactatt ttgattacta tatttgataa ttacatacaa
     5041 gataatatga aaattatgat gtctaaaccc tttagagtct tgacaataaa ttttagataa
     5101 tagataaaga attttttaaa aatttaatta tttggagaaa taattctaat agtattttgt
     5161 atttagctta acgattcgga gaaataattc taatggcatt ttgtatttaa tttaacgttt
     5221 tagagtaaag ttctaatggt attttgtatt taacctaata attcagagta ataagtctaa
     5281 ctgtattttg tatttaactt aatgatttgg agtaataagg ttaactatgt ttttgtatct
     5341 aatttaatta tttacatcta tgagattgac tagtttttat atctatttaa tataaatagt
     5401 agacctaata taaaaaccgt ttttacagta aaattgaaaa attagaaaaa agttagattt
     5461 gaaagctaaa aaagataact ttattttgta tactattttt agaaaagaag tattatgaat
     5521 tataccatag agcctactca attaaataaa atgtataaag ataaagctgt tattaataac
     5581 attaatattc atgtaagaaa ggaagtcatt tacggatttg tcgtacaaaa tagagcaggt
     5641 aaaagtacag tgatgaaaat gttgttaaac ctaactaagt caaattctgg agaaataatt
     5701 atattcggta aaaaattaga agaaactgat tttgaaatgt taaaaaagat tagtactatt
     5761 attgaaaata cttatttcta tgagaatttg actgataaac agaatcttga cttacattgt
     5821 gaatatatgg gctattataa caaagaacat atatcagaga tattgaaatg tgtcggattg
     5881 tcaaaacaat caagcaaaaa agtttcaaaa tactttttag gtataaaaca atgtctttta
     5941 atagctagag caattcttac taagccagaa ttattgattc ttgatgaatc tataaatgca
     6001 ctcgacccag agggaataag agaaatgcga gaattattca ataagttaaa tacagattat
     6061 ataacaacta tatttacttc tagtcatatt ctttcagagg tagaataaat tgcggatact
     6121 attggcatta ttcaagatgg taaacttatt aaagaaattt ctatgtcaga tatacacaaa
     6181 tatcaaacag attatgttga agtagatgta gataatgtgg agcttgttgg atacttgtta
     6241 gaaaaataat cttcctataa aaattgtacc ttgaggtagt gaggacttgt atagaaactc
     6301 cttaaattct tatagtatag gtaattatgt ccctttaatt gaatatttat taagtttaga
     6361 agattttaga gaagtatata aaatgttatg gaaataattg tttgtagcaa aaaaatatgt
     6421 tttttataca attatgtttt tacttatagt atttaatgct aatttcttaa tcattcttag
     6481 tttgaactat acccactatt ttaaccatat aaaatagtgg gtatagttta actagttatt
     6541 tataactatt tttacatatc ttaattgttc cctaataggg ggatagtcca taaaactaaa
     6601 agtggttttt aattttatca tttataactt gctattacct caaaaaaatg cttatcatta
     6661 taattttcat aaaagttacc tatttttttc aacttttttt caactagcta aatcaattct
     6721 attagtgtta atcttttatg tttcaaactt ataatacaag aaaataaaaa ataaaaaatt
     6781 ttaaattttt tatttattgc gaaaaaaata aaaaggtgtt atactttttg taacatatta
     6841 ttccaattat taagagatag taagcattta tagtttaatt tgtagtacaa tagcttaatt
     6901 ggcagtacaa tgatttaatc catagtacaa tagcatgact tgtagtacaa tggttcaaac
     6961 tatagtacaa taacgtgatt tgcagtatga tggtttaagc tatagtacaa tagcttgttt
     7021 tgtagtacaa tgatttaatc catagtacaa tagcatgact tatagtacaa tggtttaaac
     7081 tgtagtacaa taacttgact tgcagtacaa taatttaatc tatagtccaa aagtactatc
     7141 aaataagaat ttctacttta aaaacgttac taaaagtaat taaggtcaag tagttcaata
     7201 taatatggca aaagaataga aataaggtga gagtagtgaa agtaaagtca aatttagatg
     7261 aaattttata tcataagatt attgaaagtc ttattcgtgg tgaatactct gtaggtcaaa
     7321 aaatattact aaatgacctt tgtgaaaaat ttgaagtaag cagaacacca gttgtacaag
     7381 cagtaaaaat gttaaataaa gatggtgtgc ttactattat gacaaatggt aaagtgtacg
     7441 taccagagta tgaatatgat atggtaaaac aagtttgtga aacgagaaca ctgattgaaa
     7501 catacgcttt agaaaaaatg atgcaagaaa aggaagacgt ttttcaacaa aagttagatg
     7561 tgataaaaag atactctgat aaatgtgagg agtactatcg tcaggaaaaa tctgtagaac
     7621 ttgcactagc agatttggaa ttacataaag ccattgtaga aggggcaaat aatgagattt
     7681 taaatgatgt atatgttggt atacaaggaa gatttatagt agtgaactat ttaattcgac
     7741 cattaaaaaa tcgtaattat gaaggaacag tacaagacca ttttgaaata ttaaaattca
     7801 ttgaagacag agatacaaaa aaagcagtag ataaattaag aaatcatatt caaggaacta
     7861 ttaaaagatt ctgtgaagat gaataataag ttttgaagtt actatatata cttatctatt
     7921 aagttgctaa atgtagtcta agtataatct aaatgtagtt taaacataat ctaaatacag
     7981 tgtaaataag tctaagtata aattaaatat agattaagta tggattaagt atggattaag
     8041 taccaattaa gcatgaatta aatatacttt aaattacaaa tattataagg aagccataag
     8101 gcttcctaaa aaaataacct ttataaaatt ttttatttta aatttaaaat tttttatttt
     8161 aaatttaaaa taaaaaatga aagaggtggt aagaagtttg aaaaaaatta ctaaagaaag
     8221 gatagaaaac actatgaaaa agctatttac aagtgaaaca tttttggaat atcaatttat
     8281 aagtgattgc cagatatcac cagatggagg atatacagca tttattgtaa aaaaagctga
     8341 tatcaaagag aatgcttaca caagccaagt ttatatacta aacaataaaa gtggagaatt
     8401 aaaacaaata acgtctataa actctgttgg agcatatgcc tgggaagatg aaaatactat
     8461 cttgttccct gctttacgaa atgagaaagt aaaagaagct gtcaaagatg gtaaacaatg
     8521 tatgagctac tatgctttat ctttaaatgg tggagaagca gaagaacttt ttagactccc
     8581 tatcaaaggt ggtaaattga accctatagg aaaaggtttg tatgcagtta ttgattctta
     8641 tgataacgac cgacctattg tagagggatt gtcagaagaa gaacaacaga aaaaaataaa
     8701 tgcttataac aacagacact atgaacattt caaagaaatt ccttatgctg ttaatgggga
     8761 agggtatgtt agtagaaaaa gaaaacgctt atatctatat gacagtaata taaatgagtt
     8821 gaaggcaatt acagcaccta tgtttaatgt tgtaggtatg aaaataagtg atggaaaaat
     8881 cttatatgta gggcaagagt ttaaagatgt aaaaggtttg aaaaatggag tctatgtatt
     8941 tgatacaaac acaaacacaa atgtttgtat attagaaaaa gataagtata ttgtaaaagg
     9001 ttttgaatta tatcaaaatc aagtgatact aaacctaact gatgctttat cttatggaaa
     9061 tggagaaaac ggagattttt atactattga tattgataca aaagaaatga aacttctttc
     9121 agagcatcaa catcattgta ttggaaatac agtaacatct gatgttaaaa tgggtgttgg
     9181 tcagacaaca aaggtagacg gagaatatat ttattacact tctacagtag atatggattg
     9241 tattattgaa agaatacata ttccaacagg aaaacaagaa aaagtaacac agacaggttc
     9301 agttgatttt atagatgtaa aagatggcaa tattgtatgt gtagcttttt taggagatag
     9361 attaccagaa gtttatacgg tagagaatgg aacactgtgc aagaaaacac atttaaatga
     9421 ccatatttta gaggaatata aaatttctga accagaatac atagagtcaa aaggaagttc
     9481 taaatgggaa atacaaggct atgtatataa accagtagat tatgaagttg ggaaaaaata
     9541 tccagctgta ttagtgattc atggaggacc gagattgaca tatggaccat attttatgca
     9601 tgagatgcag gtatttgcaa gtgcaggtta ctttgtattc ttctgtaacc caagggggtc
     9661 tgaaggtcgt ggcaatgcct ttgcagatat taggaaacag tttggagata ttgattatat
     9721 agattttatg gaatttacag atactgtact tgaaaaatat acagacattg ataaaacaaa
     9781 attggccgta gaaggtggaa gttatggtgg atttatgacg aattggataa ttggtcatac
     9841 aaaccgtttt gctgttgctt gtgctcagcg ctctattgca aactggagtg gcatggaggg
     9901 tacaacagac attggttatt atttctgcaa aggacaaaca ggtgcttcac atatggaaaa
     9961 ccacgagctt caatggaaac agtcacctct tgcttatgct gataaatgtg ttacaccgac
    10021 tttattttta catggtgaaa aagactatag atgctatatg caagaagcat tccagatgtt
    10081 ttcagcattg aaaattcatg gatgtcctac aaaactttgt ctatttgaag gggaaaacca
    10141 tgaactgtct cgttctggta gaccaaaaca aaagctacaa agattagttg aaatgctaga
    10201 ttggttttct gtgtacataa aaaaagataa cataggacag tagagaaagg agaatataaa
    10261 aatggaaaaa ataaagattg aaaattctga tatttttgaa tatatattcc ctcatgatat
    10321 ttcttgttca cctgatggaa agcatattgc ttatattata tcaaatatca atgaggaaaa
    10381 agactgctat gaacatgact tatatgtgat ggacatcaaa acagaaaaac aaatacatat
    10441 gactcaaaca aaagatgtaa catcatttag ttggatttct aatacagaac tactttttac
    10501 atctaaaaga aataagccaa aagcaggtac aacagatttt tacactattt ctatagaagg
    10561 aggagaagca aaaaaagcat tttctatccc aaaagcttgt agcgtacctg tatcacttgg
    10621 aaataaattg tggttattga caacaaaaaa tccaacagat tctaaaaaat cagagccaga
    10681 tagggcagta gagggtatag actattggac atttacagat aaacctttta taagagatgg
    10741 agaaaacttt tctcaaagaa gacgtgtaac attagaacta tatcaagaag gtgaaaatac
    10801 aacaaaagcc attacaccaa aattttgtga agtggcgggt atagatgttt cttctgataa
    10861 aaaaagaatt ttatatgttg gtcagattta tgaagattgt gcaactcctt tttctgggct
    10921 ttgggagtac catatagaaa gtggtgaaac aaaggaactt gtaccacaag gaaaatacca
    10981 aataagtttg gcaaaatata ttggcgaaaa taaagtaatg ttgcaagctt caacattaga
    11041 ccgttctatt acacaaaatc atgatatttt tatacttgat ttgagcacta gtgaaataag
    11101 tatgattgct agtctagatg gtatgtatgc tacattactg gatgtagatg cagtatatgg
    11161 tggtggacgt agtaataaag ttataggaga taaattcatt ggtgcaagga tttgcagaac
    11221 tatgacagag tttgatgagt ttgatacaaa tacaggtaat atacgtatta tcacaaaagt
    11281 agatgctttt acatcttttg atatttatga taacactatg tatacagtaa tgttgaaaga
    11341 ttatgagttg gcagaaatat atagcattga tatgactaca ggtacaatga aaaaaatgac
    11401 tgctttttct aaaccctatt tagacactca taaggtttca ttgcctgaaa aattgacgtt
    11461 tatagcaaaa aataaagaag aagttgatgg ttttgttata ccacctatag atgctaaaga
    11521 aggcgaaaaa tatcctgctg tattgttcat tcatggtgga cctaaatggg catatggcta
    11581 tatgtttaca cacctaaagc agtgtgtaac atcaaaggga atgtatgtga tttattgtaa
    11641 ccctcatggc ggtgatggct atggtgaaaa attcctggaa atggtagaaa gatggggata
    11701 tgttgattat gaacatctta tggagtttgt agatatttgt attgaaaaat atcctggaat
    11761 tgatgcagaa cgcttaggtg ttgcaggagg aagttatggc ggttatatga caaactggat
    11821 aattggtcat acagaccgtt tcaaggcagc tgcttctcaa agaggtatta gtaacttgat
    11881 tacagcttct ttaattattg actttgggga tagaattatg aagcagactt gtggagataa
    11941 gacaccttgg aatcatgagg aggttctttg gaatcattca cctattaagt atgtgaaaaa
    12001 tgtgaaaaca ccaacattgt tcttgcatag tgatagggat tatagatgtt ttatggggga
    12061 tactttccaa atgtttacag cattaaaaca gcttggtgta gataccgaaa tgtatttgtt
    12121 ccacggagat acacatggat tgtctagaaa tggaagacca tctaatagaa tcgtacgtgt
    12181 aaatgctatt gtagattggt ttgaaagata tttataataa gggggttatt ctatgagtga
    12241 tatgttatta tggtttagtg tagtattagt tttatttgct attggagatt tgattgcaag
    12301 taaaacaaaa gcaaaagtat cagctgtatt tgttacatta cttttatttt taattctctt
    12361 tgtcacaaaa gcaataccag ctgatattat tgagaaagca ggtatgacct cagcagctag
    12421 ttggagtgtt ccaatgatta tgtttagtat gggaacaatg ttgaatgtta aacaatttat
    12481 agacgaatgg agaaccgtat tgacagcatg gcttggaatt gtagcagtta ttgtttgtgt
    12541 ctcattatgt attcctttgt ttggaaaatc aacagtatta acaagtatac cagttataaa
    12601 tggagcttta cctgctacta ctattatgac acaagcagca ttagaaaaag gattaacact
    12661 tgcagcagct acagcaacag ttgtatttgc aattcagaag tttattggta caccaatagc
    12721 ttcaagagca gcactacaag aggcaaaccg tcttttagta gaatatcatg aagcaaaatc
    12781 aaaaggcatt gatttagcaa atgttgatac tgataagaaa gaagcagaga gtacagggac
    12841 aaaagtaaaa caagctttct gtgaaaaata tgataaatat tactctacaa atgtctgtat
    12901 attttttata gcactattct cttatctagg atatgagctt tcagagatta ttcatgtaaa
    12961 ttattctatt gtatgtcttg ttgttggtgt tcttgtaaca cgtattggta ttgtgccaaa
    13021 agatattttg gaaaaaggaa aaatcaaggg atttatcaac atggttgtgt ttgcagctgt
    13081 tattccttct ttagcaaaag tctctttgac agacttaatt agtctttttg taccaattgt
    13141 aggtatgttt gcagcctcta tcattggtat attccttatg atgaaggtat taccaggttg
    13201 gaaaattatt ggttctaaac ctcttgcttt tggagtaggc ttctgtcaga tgttgggatt
    13261 cccaactaca tatttaattt caaatgaagt atgtaatgct gttggagaaa ctgaagaaga
    13321 aagagcatat ttgatgtcta aaattatgcc taagctggta gttggtggta tggcttgtat
    13381 gatttctatt gtagtagcag gtcttatggt accaatgttg tagatagatt ttatagttaa
    13441 aaaagtaaat ttaatttata gtagaatata aaaaaagaag tgccttaaag tgaactctta
    13501 gtccataagg cacttttttg tatgaatttg aatatatttt aatcatttta atattgataa
    13561 agagacttat atctagtttg agataagtct ttttaattat taaagttatt ttttatctta
    13621 tttgcataat tttatacttt tcaagtatac aattttattt ttaatataac ttttttaatt
    13681 aatttccaaa ttatataagc ataacatatg cttttaacag ctttactaat agataaggta
    13741 tagttaaatt tagtaatgaa aagtttaact tatattgagt gtaaatcttt gtattgacaa
    13801 aaaaagtgta ctaagtgtat agtgtgtata taataacatc acattgaaag tgataaaaag
    13861 gaggtgataa aaaatgaaag tcctaatttc taacacatca gataagccat tatatcaaca
    13921 aattaaagag caaattaaag aagccatatt tactgaagaa ctaaaagaag gggatgcaat
    13981 gccctccata agaaattttg ctagtgattt aaaagttagc attttaacta ttagacgagt
    14041 gtatgaagaa cttgagaatg aaggctttct tacacgtcaa gttggaatag ggacctttat
    14101 ttcaactgga aatttagaaa tattaagaga ttcgaagaga cgtatagttg aacaaaaaat
    14161 ggcagatatg ataaaagatg caaaagcact agggattaca cagatagagt tacaagaaat
    14221 gatggatatt ctatatgagg aggattaata tggaaaatat tttagaagtt tataacttaa
    14281 ataagactta taccgatttt tcattatcta atataagctt tgcgttacca gaagattgca
    14341 taactggatt tataggtgtt aatggagcag ggaaaacaac aacaatccgt tcgatattgg
    14401 atgttataaa gcgcgatagt ggaaaaataa aaatctttgg taaagacttc aatggaaacg
    14461 agaaggaatt aaaaaataga attggggttg tctttgatga ttcatatttt tatgatgagt
    14521 tgtcaatggc agaaatgaag agtattattg caccttcata tgataattgg tgcgaagaag
    14581 attatcaaaa aaatatgaag cattttaatc ttaatccaaa acaaaagatt gatacacttt
    14641 caaaaggaat gaaaatgaaa tttgctttag cattagcatt atcacataaa gctgaatttt
    14701 taattatgga tgaacctaca agtggcttag acccattaat ccgaagtcag atacttgaca
    14761 tactaacaga atacatgaag aaatgtggtc gtggtgtttt cttttccact catataacat
    14821 ctgatttaga caaaatagca gatatgattg ttatgattga taatgggcgt attatattag
    14881 aacgtgaaaa agatactctc ttggaagaac atagaaaagt aaaaggggat attaagttcc
    14941 taaatgatga aatcaaaaaa ttatttttaa atttggaaat tacaggttat ggttttatag
    15001 ggattacctc aaaaattaat gaagttcaaa aaaatatgcc agatattttg atagagcgtc
    15061 ctacaattga agatattatg cttgcgtata ttgaaaggag agagtaatta tgttgattca
    15121 tttagttaaa aaagatgttc tgattgtaaa aaaatatgta ttgtttatat tatttcttgc
    15181 tataggaata ccattattta tattatggcg tttacctccg tttgcacaaa tattgggatt
    15241 tgtactgtca attatatttt cagaatttat gctgtgccag tatctcttat taaaggagag
    15301 tcaatattca aaagcatctg tattactttg ttcaactcct tatcctagac gtggcttagt
    15361 tcaatctaag tatgttttat ttataatggt atttatctat tgtacattag tttactggat
    15421 tgaaaattta cttattccac aaatgggaac ttttgactta acatatattt tgattgtttt
    15481 actaataagt tctattattt atggagttta tatgcctgtt caatataaat taggatatga
    15541 aacaacaaaa gccttttttg tggtgataat catggcttca tcatttgtat taccattaat
    15601 tataggtcac agcaattttg aagttccatt tatatatcag tattcatcca tgatagtgaa
    15661 tattgtattg ttccttttaa gcttaattat actgttagct tcaatgttta tttctattaa
    15721 aatttttagt aataaggaac ttgtataagg taaggggaaa ttttatatgc cacatttgcc
    15781 agattgggct gttttacttt gtatcttact tccaatagta tataaagctt gtcagatatt
    15841 taaaagtaaa aaatagagta catatgtata ttgacatttt tattgagtga agttagatgt
    15901 tatgaattta gaaggttact tgaaaataaa gttacttggt gtgtgagagt aacatcataa
    15961 tattatagat tatatgtttc ttgtgaatca atttgtattc tttgatagag gatgtcaagt
    16021 aattttattt ttcattgatt atttgtcaat tatgggtata attgtgtatt atctttcaag
    16081 gtgtttttga aaatttatat cgtcaaaata taaatctaag gactccttta aataaagttt
    16141 gttaatctta gaaaactaat aaaaagtaga aaactaataa aaataggaaa tgaataataa
    16201 gaggctgtct aaaaatagag ataagcttct ttttcattgt taaaataatg aaaatacagt
    16261 tgatttcata taaaaagagt actttatgaa ctaaaagttt attttgaacc caatttttat
    16321 taaacaatat tttattcttc tcaaatagtc atctatatac agtattgtat tttttactta
    16381 tttataattt attttcttat tatagttttt ctatatttat attttctata ttactttacg
    16441 tttaacaacg tacaaattat taaaaataaa atagttatta gaaaaaaata aaagtaattg
    16501 caaagattgc aattacttac ttctatatta attactatac cataaaataa caaaaaaatc
    16561 aagtcgagta atccctcaac ttaagtgata tactaggtat taataatttt taattaaaaa
    16621 aatataacta gaggcaaatc tatattttct caatttcttt aattaaattg acctctaatt
    16681 aagtaattat aaggagaaaa attatgaact taacaaaggg attagatgtt ttaaaaattt
    16741 catcaaatgt atttggtgaa gataaagtta tgtatattcc tgtaatctac acagaagatg
    16801 aagcaacgct tattgacaca ggtcttccag gtcaaggtga tttaatagtt gatgctctta
    16861 ataaaagtaa cacaagcttt gacaagttaa aaaatataat aatcactcat catgatatag
    16921 accatatagg aaacgtaaat tatctaagag aaaaatctaa gaataatatc aaagtatacg
    16981 catacaaaag tgaagttagc tatataacag gagaagaaac tccttttaaa ctttatatgt
    17041 tagaacaaat ggtagataag attggtgata agatgcttag tatgctaaat gttatgggac
    17101 ttggatttaa atcatcatat accaaagtag atgtatcatt agataatcat gaatttttga
    17161 atctaggtga ggaaatagaa gttatacata caggaggtca tactagaggt catatatgtc
    17221 tttatttaaa agagtctaaa gtacttattg ctggagattt gctacagata gataatggag
    17281 aacttaagcc tgttgatgta atgcacagca acaaacaaga gttaaaagat gctattaaaa
    17341 atataagtaa ttatgatata gaagcgatag tttttagtca tggtggatta tatcaagaaa
    17401 atataattga aacattgaac aatataatta ttgagtagta tttattatat gattttaata
    17461 atctacaata atttcttaaa ttacataacg ttgtatttag gtgtgaaaaa ttaaaatcaa
    17521 atataaataa taaaaattag attgtatcaa taaaaatatc cttataattt atttatttgg
    17581 attctaagga tattaaatct attacaagta tatatataga tgtagttaat tacactacaa
    17641 gttaaagaat ctaaaccaac aattaaaaga aatcaaaata taaatccaat caattaaatt
    17701 cttgacatat ataaattgtt tttatccttt tttgggtgtc gataataatt tttaaaattt
    17761 aatgtcaagt aaacacaata aaacacagag cttattctaa aattatggtt tttattttat
    17821 gtatacagtt atagtattgc aagtagttta caaaatggtc tatatgtgtc aaattgaaag
    17881 tcttgtaata cttaagttga aaaatattta acatcatagt ataatagggt agaaaatact
    17941 ttaaatcaac tttagaatac aatattataa ataatcactc agatagatat tataaaaata
    18001 aaataaattc tggaaaaggc ataacatgga tgtactggat aatttagatg ataaattgta
    18061 aattgtatta tttacaacat aaagaatata acataaggga taagattgac atataaaaaa
    18121 tgatataata attatgggaa tgaggttctc ccttggatga taatatccta aactgccaat
    18181 gagctgatga cttctatgat atcatagatg ccaccagctt tttttgttgt ttaaattgat
    18241 aaaatggagg tgaaatagtt actaaattct tattgtttga atttgaataa atatttaaaa
    18301 gatagaaaaa atggcatttt atatgctaat tactttgtta gtatagagat taagagtgtg
    18361 gctatatgct attaattaaa aaaaacaatt attatagaag ccacattgcc tatagttgat
    18421 gcaataatat tttcaaaata tcttataaag caggtagaaa ggaagtaaaa tgataacaaa
    18481 atttaaaact ttaatatgga ttaaaatatt aataagaatt aaaagtgttt ataaagcata
    18541 tggaggacta tttttgttag gaattatagg tataccaatt ggtgcaatta taggtcttat
    18601 agacactgta tttggaacag ttcttctaaa aattacagat attagagaaa catatccaat
    18661 gtatttgata ccatttttat cagtagtagg tgttgttatt gcttactgtt attttaagtt
    18721 tggaggaaag agtagtaaag gaatgaatct aatatttgag gtagggcatg gagaagaaga
    18781 aattattcct ttaagattaa ttccatttat catatcaggt acatggttaa cccatttatt
    18841 tggtggtagt gcaggacgag aaggagttgc tgttcagatt ggtgctactt tttcacattg
    18901 gataggcaag aggttgccta taaaaaatgc ttctagtatt tttctagtaa ctggtatggc
    18961 agctggtttt gcaggattat ttgggacacc aatagcagca atcctttttg ctatggaggt
    19021 tttggtagct ggttcactgg agtatcaatc gctttttcct gcatttattg cttcttttac
    19081 agcaagtgaa gtaacaaaag ctttaggatt agagaaattt tcttttgcac tttcttctaa
    19141 agttgtattt gacttatcaa tattttggaa gtttattgct ttaggaatta tttttggaat
    19201 ggttggagga gcatttgcat ggtgtcttaa attgtcaaaa agaaaaatat gtaatagatt
    19261 aaaaaatcct atgataagga ttgctattat tggagcatgt attagcatat tattcctttt
    19321 atttgataaa gggagatatt ctggtttagg gacgaatcta attcaaaata gtttttatgg
    19381 tggagaaatt tattcatttg actggctgtt aaagtttgta cttacaatac tgactttgtc
    19441 ggcaggtttt caagggggag aggttacacc tttgttttct attggagcta gtcttggtgt
    19501 attactagca ggatttttta atttaccaat tgaattagtt gcagcacttg gctatgctag
    19561 tgtctttggt agtgctacaa atactttttt tgcacctgta tttataggag cagaagtttt
    19621 tggatacagc tatttgcctt atttctttgt agtatgcgct atttcatacg tatttaatat
    19681 ggataaatct atttattcgc tacaaaaaat ttcaacaaaa caataaaaaa acaacataat
    19741 atgttaatgg aatctgttta gcagtatttt taagaaagtc catatgagag attctgctaa
    19801 aagtgtttta cttttgggta tattattttt aatgataagt ttggagaatg atttagatgg
    19861 aattgtgtca ttttccggat tattagcagt tatgagtatt cttatgtcct attaagacaa
    19921 aattgatatt aaaagaaata ttattctgta tgatgggata tattccaaaa gctaaagtac
    19981 agatagcaat aggaagtgta ccacttgcaa tggagatggt atctgggcaa tttattttga
    20041 cattagcagt tctatctata cttataactg tgcctcttgg aacttttgga attgatacaa
    20101 cttataaaaa attattaaca tctgtaaaag gtgacagtaa gcaaaaataa agattatttt
    20161 aagtggtcaa ttttaaaaaa agaaccatat tatgaataca atgtcagaaa atcatttgag
    20221 agattaaaga agatagaagt tcagtatgga ttttaaggta tgtgatgatt attagaattg
    20281 attttgtgaa attattattg taatatttaa ctatatagat aaagaagcgg agtgataact
    20341 atgtatttaa aaaaattatc gaaattagag ttagttatta tgaaatttat ttggaattta
    20401 gatataaaaa ccaattcatg tgagattatt gattatatga aagaagagca taatttatca
    20461 gaaaaagtag ctttaaaaac tttatcaaaa ttatcaaaga aaagattctt atatgttcaa
    20521 gaaacagaca aatgtatgta ttatacagtt gcaataaaag aaaaggcata tcttgagttt
    20581 atatcgagaa atgtgcaaaa tcttttgaag aataatttta taaggaattt attagtgtca
    20641 tttcatgagg aggatttaac agaggaaaag ataaaatcgt tagaaaactg ggtagtaaat
    20701 tgggaggaag cttgtatata atgttattat ttttattaca atttagataa ttttggtttt
    20761 gtaagctctg caactatttt tagatggttg cagagcttat ttttattttt aatttcctta
    20821 agtaatactt aaaagtaaac gtatttatat ttactaactt caatcacttc taatacttac
    20881 gttacttttt aaaagtattt tgatatgtca tctctatagt aatctaaaac ttgtttctat
    20941 tatttatatg aagtttttaa ttattagaga tgattatatt taaaataaat tatcatataa
    21001 attatgctaa cttattagac ttgtatttaa aacatatttg gcttaaattt aaaaaattca
    21061 agttttgcat agactaaaaa aagtttttat gaatgatata tataatattc attcatttga
    21121 ttaaaaatag aaaaatatta aataattcta ctgcggtagt gtgttaaaaa aaagaataaa
    21181 aaatgttaat aaataaacaa gaattatatt aagagaaggg aattttctaa aatacaaaaa
    21241 ggtatctaga tttcataaaa aatattattt tgctcttaaa aatatttaga ttggaaaaat
    21301 tttaatttaa tgattgatta agttaaaaat gttcatggaa taaattttat tttatttatt
    21361 gactaaatta taaagtttat ataattattg aataatcatg tgattgttac ttaaaaattg
    21421 atatatttta aaatctagtt tgggtttcaa taagactgaa aattaagaaa aaagaagtga
    21481 atatatagaa ttata
//
LOCUS       DBGJFK010000068        21434 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.068, whole genome shotgun sequence.
ACCESSION   DBGJFK010000068 DBGJFK010000000
VERSION     DBGJFK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21434
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.068"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(12..581)
                     /locus_tag="ACOIAP_002822"
     CDS             complement(12..581)
                     /locus_tag="ACOIAP_002822"
                     /inference="COORDINATES: protein motif:HMM:NF024197.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HGZ2639701.1"
                     /translation="MKDYKDVVYIKLVKKELEEWKKNILKKPSIFDKTSKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRKMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLINNWDEYVSSLPEDINDFD"
     gene            complement(653..1642)
                     /gene="add"
                     /locus_tag="ACOIAP_002823"
     CDS             complement(653..1642)
                     /gene="add"
                     /locus_tag="ACOIAP_002823"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HGZ2639702.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDAFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDNKKAYNLVKDKKILLELCPTSNVQTKTVDSYETHPFYTFYKDNLHVSINT
                     DNRTVSDISLSSELNVIFDTFKLGIEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            1902..3155
                     /locus_tag="ACOIAP_002824"
     CDS             1902..3155
                     /locus_tag="ACOIAP_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HGZ2639703.1"
                     /translation="MITLTFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYNLKPSSNIDLSVPTYNRNLNRFGSKFFRNK
                     NMVKNNNFSQTITPSVFLEQVLLIFICINTGEIISRCFYIMFNILLPSVVTCMFSAVL
                     FRNLNDKISILELNFKLIDFLKEISLGIFLTLSLMNIDLFELSTLLPPILLIVIFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGNSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            3252..3476
                     /locus_tag="ACOIAP_002825"
     CDS             3252..3476
                     /locus_tag="ACOIAP_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGZ2639704.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(3932..4123)
                     /locus_tag="ACOIAP_002826"
     CDS             complement(3932..4123)
                     /locus_tag="ACOIAP_002826"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639705.1"
                     /translation="MKIGNINGQAPITNGLDSCQSEVQGLEQKKKALQDEIEKVRSDK
                     NIDSETAKLKIEDLRKQIE"
     gene            complement(4213..5571)
                     /locus_tag="ACOIAP_002827"
     CDS             complement(4213..5571)
                     /locus_tag="ACOIAP_002827"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2639706.1"
                     /translation="MINLFASDLFLKYSFLFSFTIYRILMVIVQYYFLINFTNVNSKF
                     WCFILYSIISIFLIIISTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSTVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMALSSLITIIIAGFVYWYSSKKFNI
                     KVMNFDKYLAILIIPLLLIILFMQSFKHSSNINIDTSLGTVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQSLEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKGQILKAQDYLNKLEKVTSDLSFSCNTRNVVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPKSTNMNDFDLCIVFANAIDNAIKACRVVDKQSRYLKISTKLEGGFF
                     MIEIKNSYNPINNYTSGSCIGLSNIKEIAKKYQGAISIDKTSDYFQINILLVISLHCA
                     GI"
     gene            complement(5573..6289)
                     /locus_tag="ACOIAP_002828"
     CDS             complement(5573..6289)
                     /locus_tag="ACOIAP_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGZ2639707.1"
                     /translation="MYILISIAICDDESYMLNHLKENIELYMKQNNLSYNIELFDKAE
                     DLLCNHEKFNIVFLDIQMEDINGMQTARELRVYGNDCFIIFVTVLNEFVFDAFEVDAI
                     NYLIKPLSNEKLYKTLDKIVTKLEDNESNYITIQKGYSYWKLKLADILYCEVIKRKIY
                     VHLKKETIDYYETIENLERSLPTNFFRCHRSYIINLKYVYGYESGNAVMESGDRIPIS
                     RLRQQIFSKVMLEFMKNRRR"
     gene            complement(6593..7900)
                     /gene="grdF"
                     /locus_tag="ACOIAP_002829"
     CDS             complement(6593..7900)
                     /gene="grdF"
                     /locus_tag="ACOIAP_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_082007859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(6851..6853),aa:Sec)
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     beta"
                     /protein_id="HGZ2639708.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEENPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVVTGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVNYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEAIEEQTVFE"
     gene            complement(7977..9263)
                     /gene="grdG"
                     /locus_tag="ACOIAP_002830"
     CDS             complement(7977..9263)
                     /gene="grdG"
                     /locus_tag="ACOIAP_002830"
                     /EC_number="1.21.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sarcosine reductase complex component B subunit
                     alpha"
                     /protein_id="HGZ2639709.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYINSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            complement(9542..10864)
                     /locus_tag="ACOIAP_002831"
     CDS             complement(9542..10864)
                     /locus_tag="ACOIAP_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HGZ2639710.1"
                     /translation="MKILIVDDELEYGVVMKKILQKKGYLVDVTLSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKAINKDIEVILVTGYGSIENAVDAMKKGALSYFIK
                     SNPIENLLEEVEKVKTSKTSVSLQKNNLEFTLESKNRDFNDVIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLATLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIKP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKIAEYNIK"
     gene            complement(10864..12858)
                     /locus_tag="ACOIAP_002832"
     CDS             complement(10864..12858)
                     /locus_tag="ACOIAP_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGZ2639711.1"
                     /translation="MNKKRIVIIGIIYSFLVIFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIVVDLINSLSIQIGRDFYFKP
                     NNWWKESFINSIDDSIKFFDLIPSKERASKFIFTDPIYTLSANILKDKKSEDINSYMD
                     LKGKTVAIPEGDYSINFLKQKVQDINILLTPDIKTGVNHLISGKVDAVVGDEPVLRYY
                     INNYGISNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEEVMENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDVMGEMSYKIADLIDMIKGVIENTFSENTN
                     KTSEIEVHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKILQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALRDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNREVTI"
     gene            complement(12945..14192)
                     /locus_tag="ACOIAP_002833"
     CDS             complement(12945..14192)
                     /locus_tag="ACOIAP_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HGZ2639712.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMATGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALLSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILFAMLGGGKAGNIISPNPNT
                     IAVSGNFSVNLSSVMIANIIPAIVGVIITVILASILINKGNKVQSYEILEKREDLPSL
                     FKSLCGPIIAIFLLFLGNVFPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIAALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIINSGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            14410..14955
                     /locus_tag="ACOIAP_002834"
     CDS             14410..14955
                     /locus_tag="ACOIAP_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639713.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHNNRKKVILPGSKNVVYEILIPDSS
                     GNLEFAIMNLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLFKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            14969..15655
                     /locus_tag="ACOIAP_002835"
     CDS             14969..15655
                     /locus_tag="ACOIAP_002835"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGZ2639714.1"
                     /translation="MKTYKFIFFDADDTLFDFRKSESHAFKKLLSEFNLELNFENYIK
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKINLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILPYLKEKYTIVIITNGIYEVQKKRLENSRIKGYIDGIVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMVGDSLTSDILGGINSGIDTCWLNSNNNINYTNHIPTYEI
                     NTLLELNKLL"
     gene            complement(15779..16399)
                     /locus_tag="ACOIAP_002836"
     CDS             complement(15779..16399)
                     /locus_tag="ACOIAP_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639715.1"
                     /translation="MNYNSNKDKFILADINLADIFIDKNIVLKFLGYGNRKAPDTISE
                     IVEREIRNINDILDIKIYISEVNIDKTPKECKKAFAVMYTIGDKIDIKMNDYMKNCNM
                     MAGLALDKIGIVCLDCINEKIKMYLKEKYDSLKISHEIYPGDKEFEVERQKDIYNYIK
                     NKYSSVEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(16389..17411)
                     /locus_tag="ACOIAP_002837"
     CDS             complement(16389..17411)
                     /locus_tag="ACOIAP_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="HGZ2639716.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDREKLRKL
                     DVPDPYTSGRMPLNIESLSLISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEYIVKNLNKIYDEL
                     DCWKGMHICGDTRELLDNMLDCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDINEL"
     gene            complement(17412..18050)
                     /locus_tag="ACOIAP_002838"
     CDS             complement(17412..18050)
                     /locus_tag="ACOIAP_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HGZ2639717.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINILKKTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNRIKVDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(18177..19328)
                     /locus_tag="ACOIAP_002839"
     CDS             complement(18177..19328)
                     /locus_tag="ACOIAP_002839"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639718.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIPYEIVEFDETNF
                     EKDDDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGTIAYNKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     IKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDSELLKYMEFKQVENKYIIKYKEEELV
                     IESLDKLNKLFFEKNEEQYNEFKHLKNIYKFATKAFPVDFPWTANLNYQ"
     gene            19750..20562
                     /locus_tag="ACOIAP_002840"
     CDS             19750..20562
                     /locus_tag="ACOIAP_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HGZ2639719.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNRVTEISDDLDSILTNVVEKIK"
     gene            complement(20650..20841)
                     /locus_tag="ACOIAP_002841"
     CDS             complement(20650..20841)
                     /locus_tag="ACOIAP_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639720.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTKPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(21073..21330)
                     /locus_tag="ACOIAP_002842"
     CDS             complement(21073..21330)
                     /locus_tag="ACOIAP_002842"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639721.1"
                     /translation="MHNVDCNDKSVYIGNNELDRSKYLKENELLALFGDGASIDMKHN
                     SKLDMQISNPNLKSVNIYPYTPFVGLRGTLYIIEKILNIQY"
BASE COUNT         7108 a         3465 c         2247 g         8614 t
ORIGIN      
        1 gtagctattt tttaatcaaa atcattgatg tcttctggta gactacttac atattcatcc
       61 cagttattta tcaatttaaa agttttattt atatgctgtt ggctagaaaa agccaactgt
      121 aatatgttta atatataaat cctttctcta taatctttaa catcatatcc atatattgaa
      181 gctacatcat atagaaattt tactttaata cctaaaagta aaggaaaatc agataaacct
      241 aagaggattc ctcctgcccc tgttcctgct ccttcaatca ttgctgtggt cttgtatgtt
      301 ttagcttttt ctaaaactaa tttttctctt tcttctaatg acatctttct aagtggtggc
      361 tttgtggcat atttatatcc aaacaataca gtttttgtca ttacttttat agaagaagta
      421 attatttcat gatatttatc tggcaatact ccattaaact tattctgtat cccctttgat
      481 gttttgtcaa atatagaagg tttctttaat atatttttct tccattcttc aagttctttt
      541 ttgactagtt taatataaac aacatcttta taatctttca cattttttct cctaatacaa
      601 tgtatttttg tcaatttaat agcttaattt aaagtttata tatttttatc tattaaatta
      661 aactattcaa atactcttta gtttctttgt ctgcaaaact agcttctact gcatttctat
      721 aaattatttt atagtcttct attcctagtt taaaagtatc aaatataaca tttagttctg
      781 aacttaaact tatatctgat acagttctat tatcagtatt tatacttaca tgtaaattat
      841 ctttataaaa agtataaaat ggatgtgttt cataagaatc tactgtctta gtttgtacat
      901 tactagttgg acataattca agcaatattt ttttatcttt aactaaatta taagcctttt
      961 tattgtcttt aatttttacc ccatgaccaa tcctatccgc ctttaaaata tttatagcat
     1021 ccaatacatt ttctccactt gcagcttctc ctgcatgtat tgtaacttta taaccatatt
     1081 ctcttgctaa tttgaaagca tctttatatt ccttacaaaa tccctctttc tctggaccac
     1141 ataagtctac tgctacaaca cctttattta caaatgattt cccttcttca attactaata
     1201 atgcctcttt tgaggtcatt gttctcatac aacctaatat taaattgcct tttatatcat
     1261 aaatactttc agcttctcta attccttcaa ttataccctc aattatattt ttaacactca
     1321 tacctttttg ggtgtgaagt aatggtgcaa atctaatctc aatatatttt acattttctc
     1381 tacttgcatc ttccaaaagt tcaaaagtaa ttctttttaa attttcctta gattgcatta
     1441 cttttaaagg taaatcaaat ttttctaaat attcatcaag tgaagtacaa ttaaaagaaa
     1501 cctttgctaa tttttttatt tcatccatat tatttgaagg taaatctatt ttctctttaa
     1561 tagctatatc aagcatggtt tctactctaa cacttccatc taagtggcaa tgtaaatcta
     1621 tcttaggtaa attttcaaac attttatcct cctactgtac ttataaataa tactatcaac
     1681 agatttttaa gtcttatttc tattatatca atatactacg atttttcatt ctaaaaaagt
     1741 cacatctcat taaaatattt taatttaatt tatgactatc taattatatc tactgattct
     1801 ttttaatata catttattaa tatacatttg ataataaaat ttcaatacat aaaaatttaa
     1861 gttatataat taaaacttta aattacaaag gaggacttat tttgattacc ttaacttttg
     1921 atatagtgca aaccttgaca ctatctatat tcttcttttt aattggtaat ttattgaaga
     1981 ataaagttaa ctttttaaac aatttctgta tacctgcacc agtaatagga ggtctattat
     2041 tttgttttct aaatttattt tttaaatatt ttaatatagc agatatatct ataagtggaa
     2101 atttaatgcc aaattttata accttctttt ttacaactat aggacttgaa ataagtataa
     2161 atcttataaa gaaaggtggt agtgtattat ttagatattg gattttgtgt ggagtattgg
     2221 cattttgtca aaatatctta gctattacaa tatcaaagat tataaaactt gaacctcttt
     2281 tagggcttat gtgtggaaat gtatctatgg aaggtggtca tggttattct gctgcatttg
     2341 gacttacaat agaaaatctt ggtatagaag gagcagttgg agttggctta tctgctgcaa
     2401 caataggact tattatgggt ggtatattgg gatgtcctgt agctaaattt ctaataaata
     2461 aatataattt aaaaccatca tcaaatatag acttatccgt tcctacatat aatagaaatc
     2521 taaatagatt tggaagtaaa ttttttagaa ataagaatat ggtaaaaaat aataacttct
     2581 ctcaaacaat aacaccatct gtgtttttgg aacaggttct tctcatattt atttgcataa
     2641 atacaggaga aattataagt agatgcttct atataatgtt taatatccta ttaccttctg
     2701 ttgtaacttg tatgttttcg gctgttcttt ttagaaattt aaatgacaag ataagtatac
     2761 tagaattaaa ttttaagctt atagactttt taaaagaaat ttcattagga atttttttaa
     2821 ctttatcact tatgaatata gacttgtttg aactatctac attattacct ccaattctct
     2881 taatagtaat tttccaggta atctttataa tcctattttc aatatttatt tgctttagag
     2941 tacttggaaa agattttgat tctgccatca taataagtgg tttgattgga catggaatag
     3001 gagctactcc aaacgctttg gcaaatatga gttctttgac acaaaaatat ggaaattcgc
     3061 caaaagcatt tttggttgta ccattggtaa gtggtttttt gctagatgct attagtatcc
     3121 catgcatact tttttttata aacatactaa cttagtatgt ttattttttg ttatatattg
     3181 acaatttgct ctttttgtta tatattataa atataaagtt tgataatgat tttcattagg
     3241 aggtgttaat aatgactgtt tacaacttga aacttggaca aaagggaatt atagacaata
     3301 tagctggaaa tgaaaaactt atgaagagac ttctagcctt aggattaata gatggcactg
     3361 aagttgaagt gaaaaagata gctcctctta atgaccctat agtgattaga tttagagggt
     3421 ttgacttagc tattagaaaa tctgatgcaa aaaatataaa tttaaaaaat aattaataaa
     3481 taaaaaagag attttagaat ctcttttttt gtttatgtat agataaatgt gaataaatat
     3541 ttaagcatta tataccatgt aaaagttatc aagatagact tgtaaataat agttataaaa
     3601 ccacctataa atgtactaac tgtaaataaa ttgtgtattc tactaaaaaa tgttgataat
     3661 taaaatatca actattttta taaataaact atataggcct attaaatttt acttttaagt
     3721 ttttatcatc ttgaacaaca tgataagtat tatcccattg ttcgtctgca ttgtttcttt
     3781 caaaaacatc atataattgt tttacatttt cattattaga aggttctttt tttctgtcta
     3841 atagattatt atttacttct gaaacgttat tttcttcttt atttgtttct tgtgctttat
     3901 ctccttttaa ctcttgaatt ttactttcaa tctattctat ctgttttctt aaatcttcta
     3961 tttttaattt ggccgtttca ctatcaatat ttttatcact tcttactttc tctatttcat
     4021 cctgtaatgc ttttttcttt tgttctaagc cttgtacctc actttgacaa ctatctaagc
     4081 catttgtaat tggtgcttga ccatttatat ttccaatttt cattttagta acctcctcat
     4141 ttctatatat caaactttct ttattcaaat acataatata gcttataaac actattttca
     4201 atgaaattgt tctcaaatac ctgcacaatg taatgaaata actaacaata tatttatttg
     4261 aaaataatct gatgtcttat ctatacttat agccccttga tatttcttag caatttcttt
     4321 tatatttgaa agccctatac atgaaccact tgtataatta tttattggat tatagctatt
     4381 ttttatttct atcataaaaa atccaccctc taatttagta gaaatcttta aatacctact
     4441 ttgtttatct acaactctgc aagctttaat tgcattgtca atagcattag caaatactat
     4501 acataggtca aaatcgttca tattagtgct tttgggtata attacttcac aatccacctc
     4561 tatgcctaat tgttttgcta tacttagttt attgttaaaa agagcatcaa taacaacatt
     4621 ccgtgtatta caagaaaatg ataggtcact tgttactttt tcaagcttat ttaaataatc
     4681 ttgtgctttt aaaatttgac cttttttcaa taatccattg acaatagcta aatgattatt
     4741 aaaatcatgc ctaaaggata tagtttgtga taatcgtgat ttcgcttctt caatatagtt
     4801 tttttgagca tgaatctgtt gattcataat tgccctctcc ttgtcatctt cgagagattg
     4861 aattagtttc ttaaaggtaa ataaagaaaa aaatacacat atagttccaa ttatagaaaa
     4921 aagaaaagct tgaatttctt cagttataga agtatttaat agcaacttta cagtaccaag
     4981 acttgtatct atatttatat ttgaactatg tttaaatgat tgcataaata atattataag
     5041 caacaatgga attatcaaaa ttgctaggta tttatcaaag ttcataactt taatattgaa
     5101 ctttttagaa ctataccaat atacaaatcc agctattata atggtaatta aagaagatag
     5161 tgccatattt atatcaaatt tataaatatc tgtatttata tcactagtaa atatcaagta
     5221 atttaatgga gctgtaaatc catatactaa ttgttcaatt aaatatacta ataaggttga
     5281 tactgtagat aaaacagtag attgttttat tatgtacttt acaaataaaa aagtcataag
     5341 aaaaaataga atctgtgaag aaaataaatt atataaatta aaatatgtac ttatgatgat
     5401 taaaaaaatt gaaattatcg aatataaaat aaaacaccaa aattttgaat taacatttgt
     5461 aaaattgatt agaaaatagt attgcacgat taccatcaaa attctatata tagtaaaaga
     5521 aaataaaaaa ctgtacttta aaaataaatc agaagcaaat aaattaatca tcttatctcc
     5581 tcctattttt catgaactca agcataactt ttgaaaatat ttgttggcgt agtctagaaa
     5641 taggtattct atctccactt tccataactg cattaccact ttcatatcca tatacgtatt
     5701 ttaaattgat tatataacta cgatgacacc taaaaaaatt tgttggtaaa cttctctcta
     5761 aattttcaat agtctcataa taatctatag tctctttctt taaatgaaca taaatctttc
     5821 tttttataac ttcacaatat aaaatatcag caagttttaa tttccaatat gaataacctt
     5881 tttgtattgt gatataatta ctttcattat cctcaagttt tgtaactatt ttatccaaag
     5941 ttttatatag tttctcatta gatagaggtt ttatcaaata atttatagca tctacttcaa
     6001 aagcatcaaa tacaaattca tttaaaactg taacgaaaat tataaaacaa tcattaccat
     6061 atacccttaa ttctctagct gtctgcattc cattaatatc ttccatctgt atatctaaaa
     6121 atacaatatt aaacttttca tgattgcata gtaaatcttc tgctttatca aaaagctcta
     6181 tattatatga taagttattc tgcttcatat ataattctat attttctttt aaatgattta
     6241 gcatatacga ttcgtcatca caaatagcaa ttgaaatcaa tatgtacatc ttctttcttg
     6301 tcattattct aattattata taaagttaat tttttctgtt caattaatat gttctagtat
     6361 gttgaatatt tgttccaaaa tgtaataagc tcacttttca tagtatatct aatttaaatt
     6421 tatgtatcaa tattataata aattaattta ttatttttat aaatttaatt taaaaatgta
     6481 caaatagtat tcaatatttc gaatttatct aacaaaaaaa ggtatcgtaa aacaatttta
     6541 aaaaactatt tttcgatacc ttttttaatt ttaatgttgt gttatatttt tattattcaa
     6601 atactgtttg ctcttctata gcttctgtta gtgcatttaa agcttttaaa actatattct
     6661 ttctaatttt tttactttcc tcttctccta acataggatt tccaagtgga tatggtatcc
     6721 ctactgctgg aacaattcta ttagctccta ttgtaagtga tattggtact actgtacata
     6781 tatgaacaac tgctatacca gctctctcaa tctcttttac catcgttgct ccacaacgag
     6841 tacaagtacc tcatgtagaa gttaaaatta cagcatctac atcatcttct aacaatttct
     6901 tagaaaactc ttctccaaat cttttagaat taccaacact cgttcctgtt cctgtagtag
     6961 ttataaaata atttactaat tctccaatta caccttcttt ttcaagttct ctaactacat
     7021 ctagtggtac aactaaattt ggattttcaa gaacatatgc tctatcatac ccaccatgta
     7081 tagttgtaaa ttctttattt gacatagaat ccatatctgt taaatcataa attccatatt
     7141 tagtagcact tgaagattca attttatctg gattatcaat tggaactata cctccagaag
     7201 ttactagtgc aagttttatc ttagataaat ctttaacagg tttcataggt gtaactctat
     7261 caaattcagg cattggatac tcagtttcaa agctttcacc tttcattttc ttaactaaca
     7321 tatcaattgc tctttcagac cctctaagct catggaagaa attctttctt attcctctca
     7381 ttatatatcc ttcttcttca ggaggtccta tttcctcacc tctaaccaat ttaagaccta
     7441 gtttcgtcat tattggaact acctttctaa gacttgctgc tgaatttcct gtagatacta
     7501 tatgcaaatc taacttaaac atatctacac ctggattttc tttatacatt cctgtaacta
     7561 caggaatatt tagctcttct tcaactgcct tacaaatagt cccacaagct actccatatc
     7621 tacctgcatt aaatgctgga cctgcaataa ataaatcagg attttcttct tttatcattt
     7681 ttaaaagttc ttgagttgca ctctcaatat tttcaccaaa atacgtatct ccacaaatta
     7741 cagttgagat tatctctgca tcatcattaa attgactctg aaatgctatt ccaggtccta
     7801 ctacaccagc ccttttttct ggcggaatat ctgctttttc ctctccacct ataccagcaa
     7861 agaaattgtt tatataatga accactctga ttttactcat cttttaaccc tccaaatcac
     7921 tttatagtta ttacatcaat gattacacca acagaacttt atattcaaat gcttatttaa
     7981 taatatcttg ctgtcaaatg attatagcca tttgctatag ttgatgctat tataatttgt
     8041 aactctgcat ccatgcttcc atcttcattt aagcatcctt tatacccacc tatcatcatt
     8101 tcaacatagt ctaaagttcc tataattttt tccattgctg ggaaatgaac cactagattt
     8161 ccttgaccac aagaaacaac tgcatctgct tccttagtag catctgctat agattgactc
     8221 ttgccatctt ttccaggaaa ttcatctgtt atcaaaacta catttgctcc aacttcacta
     8281 cattttctac aattcatcat taggtcagta tctggatttc cataaccttc ttctgtcact
     8341 agaactccat caactcctaa aaattctatt aatttagcta ccatatcaga gcttctctct
     8401 ttatcaacta aaaatacatt ctcattagtc aaaataactc ctataaagtt taaatctttt
     8461 ccatgtcttt tatataagtc atgtataact ggattattta aatgatggaa tgtcgtaacc
     8521 ttatcacatg gtgctacaca gtttccagat attatagctc catccattat ttcagttgga
     8581 tacataaatg taggaactat ctgtttagca tccaccccgt agtaataagt atcatgtaaa
     8641 agtccttgtg attgtaacat atgaacatat gctactgttg gcaggtctgg atattctttt
     8701 acttgtttta ataatggctt tgtctcatat acaatgactt catctggctc aacttctctt
     8761 cctgcttcgc ctacgtatgc acctattttt aatccagcaa ttctagctgc ttcttcataa
     8821 tcatgagtat ctataccatc ctttgctttt ataacaatac atatattatt tgtttttgaa
     8881 aaaggtgtat atttagcagt aggaccactc atatcaatta cgccttcttg aaatccaact
     8941 atatttccac aagttacaac acaagctcct aaaagtacat gggttcttcc acttcctaca
     9001 gtcttcactt tatttataat tccaggaaat attttgcttt catctccaat tttaactcta
     9061 ggttctatta catctttaac tggagctatt cttattgatt cgccaggtct tgcaagttca
     9121 acatttacac ttacaatcct ttcatcttct aatactattt tttctatttc ttcgctattg
     9181 atatatagta ccccatcttt tacttctgtc ttttctccaa attcaacatt ttttataaat
     9241 atattcccta gctctagctt catatgaaaa tcccccttaa catatttaat cgcaattaaa
     9301 agtatttatt acgtttatta atgtatgaag cattttctat gccaactatt taaaatatat
     9361 attctatgta ttaatgtcat agaaatttgc atttttaatt tacatcagta ttgaatttac
     9421 caataatcat tgtaaatatt aatttttaaa attataataa aaaaagataa acagattttt
     9481 tctgtttatc ttttagtaca gtttgagaaa tttttttctc acttaatgag aagttttttt
     9541 ctcacttaat attatactct gctattttat tggttaactg tcttctacta atctccaatt
     9601 ttttagctgt atttgaaata ttatttccac ataaagataa aactttttca atatactcac
     9661 attcaaactc ttttcttatt tctcttaaag gtttaatact tattttatca tctatataca
     9721 cattatttga tattaaattt aaattatctt ttgatagatt accttcttcg cttaaaacta
     9781 caagtctatt tattatattt tttagttctc ttatatttcc tggataattg taatttaata
     9841 aaaagtcttt tacttcctta tcaattgagt gtatcttttt atcatgttct atttgatact
     9901 tatttaagaa aaattctata agagtagcta agtcttctct tctctttctt agtggtggta
     9961 tagttattgt tatcgtactt attctataaa aaaaatcttc tcttatattt ccatttgata
    10021 tttccacttt tggttcctta ttcatagcac aaattaatct aaagtcaact ttaatagatt
    10081 tattgcttcc tatcctctct atagatttgt cctcaagtgt ccttaaaagt tttacctgaa
    10141 catttaaagg tatatctcct atttcatcca aaaataaagt tcctttattc gaaagttcaa
    10201 atctaccttt tctactatct actgctcctg taaaagaacc tttttcatga ccaaataact
    10261 cagactccaa tagattttct gaaaaagagc aacaatttac aggtacaaat atctcattct
    10321 ttcttggact tatgctatgt atatatctag ctaatatatc ttttcctaca ccagattcac
    10381 ccaagattaa tatattaaca tctttacaag cagctttttt tgctattttt atgacatcat
    10441 taaaatctct atttttagat tccaaagtaa actccaaatt atttttttgt aaagaaacag
    10501 atgttttact tgtctttact ttttcaactt cttctaataa attttcaata ggattacttt
    10561 ttataaaata agataaagct ccttttttca tagcatcaac tgcattttca atacttccat
    10621 accctgtaac taatataacc tctatatctt tattaatggc tttaattcta tctaatagct
    10681 gtactccatc catatttttc atcataacat cagataaaac caaatcataa tttttatctt
    10741 tcttaattat atttatagct tcttcaccac ttagtgttac atctacaaga tagcccttct
    10801 tttgtagaat ttttttcatt actactccat actctagctc atcatcaact attagtattt
    10861 tcattatata gtcacctctc tatttaatgg aatttttata tgaaaacaag ttccaacccc
    10921 caatttactt tcaacactta tatcgccatt attcttttta atctcattat aagtaatgta
    10981 taaacctaaa ccagttccct caccaattgg ttttgtagta tagaaaggat taaatatatc
    11041 ccttagagca tcttctttta ttccttcccc attatcttta aagtctataa ataaacaatg
    11101 atttttttca tagcaatata taataatttt tccatcttga tgtattgcat ctattgaatt
    11161 agaaattaaa tttataaata catgttttaa tgattctcca tttatatagc aaactaaatt
    11221 atgttcacaa tcaattttta tttcaacatt ctttaactgt aatattttat attgaagttt
    11281 cactatattt tcaataaaat ttcttatatt tatatgttct aaattatcat ctgatattct
    11341 cgcaaaattt aacaaattag ttattatgtt acttgcccta tctacattac tttctattga
    11401 tttaacacaa tcatttactt cttccattgt aacgttatct tttaagagat agcaattatt
    11461 tcttattata cctaaaggat ttcttatctc atgtgctacc ccagaagcta attgtcctat
    11521 agatatcatt ttgttttctc taagtaattt cgcctctact attttatcat tagttatatc
    11581 tttaataaga actactatgt actcagtatt atttttttta tactctacag gaaaagtatt
    11641 tatctttaaa atcttattgt gtacttctat ttcactagtt ttattagtgt tttcagagaa
    11701 ggtattttca ataacacctt ttatcatgtc aatcaaatct gctattttat aactcatttc
    11761 acccataaca tcatatagta ctttgttcga ttctactata ttgttatttt catctacaag
    11821 cattattata tctgtgatac tattaaaagt tgcctctaaa gtttttttat tttccattac
    11881 ttcttctgtt tttcttttta tttctatctt taacaaatat gtatagctat aaaaaacata
    11941 aattgatatt aaaattatac ctataaaaag ataaatacta ggtacaattc ctcgctcata
    12001 caatatatca tcaacttcat tatatgtaga ataccatttt ttctttaaat ctttatacac
    12061 tccatttttc tgaagtttaa aaatgccttt atttaaaata ctgaccagct cttcatattg
    12121 tttaggtaca gcaagaactg cctttttagt atatatagga ttacttagaa cactgtattt
    12181 atttgaaatt ccataattat ttatataata tcgcaatact ggttcatcac caacaactgc
    12241 gtctactttt cccgatatta aatggttgac tccagtcttt atatctggag tcaataaaat
    12301 gtttatatct tgaacttttt gctttaaaaa atttatagaa taatcacctt ctggaattgc
    12361 tactgttttt ccctttaaat ccatgtaact atttatatct tcagattttt tatcttttaa
    12421 tatatttgca ctcaaagtgt atattgggtc agtaaatata aatttacttg ccctttcctt
    12481 tgatggaatc aagtcaaaaa actttatact atcatctatt gaatttatga aagattcttt
    12541 ccaccaatta ttgggtttaa aataaaaatc tctaccaatt tgaattgaca gagaatttat
    12601 taaatcaaca acaattccct tatattgtcc atcttcttta cccttatatc tcaaaggagg
    12661 tgaactttgg tcagaactat aaatcaaatt cttgtgtttt tctaaccact ttttttcttc
    12721 ttctgtaaac ggaagtgatt tcttaatata ttcaaataca tttagattat actccatatt
    12781 tacatacata tttgtaagtg aaaatatcac taaaaaggaa taaataatcc ctataataac
    12841 aatccttttt ttattcactt taaaactcca atcttctttt ttactataat aaattcaata
    12901 tttaataaca aaatcctact tttttcattg aatatttata tttattataa aactaattga
    12961 atagatgttg aaattatagt cattactatt cctatcagtg cttcatatgg aattaattta
    13021 aatctttcac ctatatccat atttatacta cctgcactag tatgaaatag tgagccatgt
    13081 ggtaattgtt caaatacact agacccagaa tttattattg atgcacctga aattggtgat
    13141 aatccaccat ttattatagc atcatgaaaa gtagatgatg ctatagtagc accagctgtt
    13201 gatgatgctg ttgctaacga cataagtata cccgaaactg gtgccaataa aaattgtggc
    13261 atatttaaaa attgtagagc agctattgtg ctctgttgta attcagacat ctgtataatt
    13321 cctgcaatag tccctgttcc aagtaataat atacagaccc cttgcatctt agataatcca
    13381 aaagctaaat attctcttga attgttcaaa tttcctgtga caattagagt tactattcct
    13441 cctattggaa gagctatcat ggggtctata actataggaa atacatttcc taaaaacaat
    13501 agaaatatag ctatgattgg accacataat gatttaaata aacttggtaa gtcctctctt
    13561 ttctctaaga tttcatatga ttgtacttta ttccctttat ttattaatat acttgctaaa
    13621 ataactgtaa taataactcc aacaattgct ggaattatat ttgcaatcat aacactagag
    13681 agattgacag aaaaattacc tgatactgct atagtatttg ggtttggtga tattatatta
    13741 cctgctttac ctcctcccaa catggcaaat agtattgaca atttagaata atttaatttt
    13801 ctacctatat ataatcctat aggtgctaca gttattatag atacatccaa atttactcct
    13861 actccagcaa gtaccatagt tgaaatggca atcgaaagta aagccctctt ttcaccaaat
    13921 atttttacaa tctgttctga tattttatct actgcccctg tttttattaa acttccagct
    13981 aatacacctg atgccaaagc tctaagaatt gatggtgata tattcatagc tccagttgcc
    14041 ataaaatcta cagtttgtgt tatgtttgct cctccaacta atcctccaat aaatgctcct
    14101 aacattaaac tatatacagc ttgaaatttt tttataatta aaataattgc tattaataaa
    14161 ccaaatatag ctccaaaagt cgttatttgc ataatatccc ctcctatcat aaattaatta
    14221 tcttttattt aaatatattt taagtattct gtatccactt tgtcaattat attttaattt
    14281 gtttaattag attgaacata gttttttcaa aacctcattc tatatgttat aataatttca
    14341 tactatataa tctttttact tgattatttt aagttaatat tttttaaatt aaaaagagag
    14401 gatatttata tgaatgattt aaatttaggt gaaaaaatag ctgaagttcg aaaaaaacaa
    14461 aacttaagta ttcgagattt agcaaaacta gctgatgtta caccatcatt attaagccaa
    14521 atagaacgag gtcttgctaa tccatctgta aattcattaa aatccatagc ctcttctcta
    14581 aacgttcctt tatttacatt ttttgtatct gaggtagata aaaaaaactt gatagtaaga
    14641 cataataata gaaaaaaagt tattttacct ggaagcaaaa acgttgtata tgagatttta
    14701 attccagatt ctagtggcaa tttagagttt gcaattatga atttagctcc aaatacttct
    14761 tcttgtgttg atagaattac tcataatgga gatgaaattg catatgtttt ggagggagag
    14821 gttaaacttt tcatggatga tgatgaattt actttattca aaggagatag tgtaaaagtt
    14881 cctttaggaa caaagcataa atggcaaaat gactcaaata gtgaaagtaa agtaattttt
    14941 gcagttatct tgtaaaggag taaaaaccat gaagacatat aaatttatat tttttgatgc
    15001 agatgatact ttatttgatt ttaggaaaag tgaatcacat gcttttaaaa aacttctatc
    15061 tgagtttaat ttagaactta attttgagaa ttatataaaa tcatatagaa atataagtga
    15121 taagctttgg cttgaccttg aaaaaaatat tataactttg aatgaactta aattacttag
    15181 atttgaactt tttgcaaata aaataaattt ggatgttgat tctgaaaccc ttagcaaaat
    15241 gtacttaaat tttttaggtg aatgtacatt tttaattcca ggtgcaatcg atatattgcc
    15301 atatcttaaa gaaaaatata ctatagttat aataacaaat ggaatttatg aggttcaaaa
    15361 gaaaagactt gaaaattcaa gaataaaagg atatattgat ggaatagttg tatctgaaga
    15421 attaaaaata tcaaaaccaa atcctgaaat atttaaatac gctctcaaaa agtttaattg
    15481 ccatgataaa tcttctgctt taatggttgg tgatagctta acctcagaca tcttaggtgg
    15541 aataaattca ggaatagata cttgttggtt aaattccaac aacaatataa attatactaa
    15601 tcatatacca acttatgaaa taaatacact tcttgaatta aataaactac tatagcttgt
    15661 aaatctgttc agattaaaca gaatattatt ttgcaataat ttttttagtt tatatacaaa
    15721 ataactaaaa aaattattgc aattcataca cagaacaaat ctcagtcttg aaaactatct
    15781 aaaaacattt tctaggacac ttactacatc ttgattctaa attttcttca tcccccatta
    15841 aaataagcat tgcaacactt tttatgggcg atagttgatg atagtcattg atttctattt
    15901 ctacactact atatttattt tttatatagt tataaatatc cttttgtctc tctacttcaa
    15961 attctttatc tcctggatat atttcatgcg atattttgag actatcatac ttttctttta
    16021 aatacatttt tattttctca ttaatgcaat ctaaacatac tatacctatt ttatccaatg
    16081 ctagtcctgc catcatgttg caatttttca tatagtcgtt catcttgatg tcaattttat
    16141 cccctattgt atacattaca gcaaatgcct ttttacattc tttaggtgtt ttatcaatat
    16201 taacttcact tatatatatc ttaatatcta aaatatcatt tatatttctt atttctcttt
    16261 caacgatttc actaattgta tcaggagctt ttctatttcc atatcctaaa aactttagta
    16321 caatattctt atctataaaa atatccgcta aatttatatc tgctaaaata aatttatctt
    16381 tattactatt ataattcatt aatatcaatc ctatctaatt ctttataact aattcttcct
    16441 gcctttatag ctgcttgtaa attttctact ggagtggtat ttaaacagtt acatccaaaa
    16501 tcacataaaa aattatcata tcctctcatc ttctttaaca attttagtgt ctctcttcta
    16561 attttatctg gtttagaacg tccaagaagt tttattgggt ctaaattacc aatcaacact
    16621 atatctctag gaatcattgg agcaatttct tcatagtcta aaatttggtc taaacttact
    16681 gcatctatat tgcaatctaa catattatct aataattctc tggtatctcc acatatatgc
    16741 atacctttcc aacaatcaag ttcatcatag attttattta aattttttac tatatattca
    16801 tcaaatctat ctttacttag agttactgat gttggctctg ctattgaaat atactttgct
    16861 cctgctttat ttgcagccac agcatatctc cttaccaatt cagttgtaaa ttccaacaat
    16921 tcttctacaa attttttatc agttattata catcttaaaa gttgagtagc tccagctaat
    16981 tgacctgcaa gtgtaaatgg accttgtatc gattcatata gtggcttttt aatacttttt
    17041 gatatcagtg ataagctttc tatattgagt ggcatacgtc cactcgtata agggtctgga
    17101 acatctaatt ttcttaattt ctctctgtca gttatagtat gtgtcaatac acttggaaaa
    17161 tcataatctg gtcttaatgt ttctaaaccc agagtttcac aaaatgtaat cccatcacag
    17221 aatgagtata taaaatctga ttcaaaatat ttgtccatag tctttgctaa ttctaattgc
    17281 aaatctacac tatcatatac ctcatatgcc tttttattta ttaagaacaa tccatttgtt
    17341 cccatatcag gtagaaaaaa acctctgtct tcactattta tatactgaag taaagtcata
    17401 tctgaaaaca tttaaacttc acctcctata agtttattta ttaatttgac tgcttttgga
    17461 gcatttgaac tatatccatc tgctcctatt tcttctgcaa actccatact tacaggacct
    17521 ccaccaatta ttacttttgg tcttttatct accttaatcc tattaagttc atctataaca
    17581 gatttcatat tctccatagt agttgtcatc attgaagata agcctattat atccacattg
    17641 ttttttatag cttcttctat tatgtcttca ctttttctat ttacacctaa gtcaataact
    17701 ttatatccag tggcttctac cattactttt acaatatttt ttcctatctc atgagtatct
    17761 ccttctacta cagacattag aattactccc tttgattttt tctttacttt tccagttttt
    17821 ttcaaaatat taatgccttt atttaatgca tctgtgcata ctataacttc tgaaagatag
    17881 tattctttat tttcaaattt atctaaagct cctatcatac ctttgtttaa accatattca
    17941 taaatatctt ccacatcaat atttttatct atagcaattt ttactaaatt ctctatatta
    18001 tctacaccca tatttaatat acattctgct atatcatcaa gtatgtccat ataatactca
    18061 tcctttctaa ttacttacaa aattaccttt tcaatatcca ataatttctt ttatttaaca
    18121 aggactagct ctaggtatca atcaatttta tttaatatca tctaaaagta caacaactat
    18181 tgataattta aatttgcagt ccatgggaaa tctacaggaa atgcctttgt agcaaattta
    18241 tatatatttt ttagatgttt aaattcattg tactgttctt catttttttc aaaaaacagt
    18301 ttattaagct tatccaaact ttctattaca agttcttctt ctttatattt aataatatat
    18361 ttattttcaa cttgtttaaa ttccatgtat tttaacaatt cagaatctac atattgacta
    18421 aaataacttc ttaagctatc acacaactta gtaaaattta ttattttcat agttccttgt
    18481 tgatagtcca aagattttat cccattacat ttcaactggt ctttaagatt tttcacatgt
    18541 actttataat ttaaatattc taatccgaat ttatttgcaa catatttcaa tatattttca
    18601 acatttacag agtttaaccc tatttcagca acttctccta cagtagagtc ttcttttttt
    18661 attgttctta ttatcaaata tcctattata ttattatttt cctttataaa taccttattg
    18721 taagcaatcg ttccccaggc aatagttgct gcatgcaata gtttttgaaa ctcatctctc
    18781 gttcttataa atctagtact attttgatta tatagttcaa tcattttatc taaatcatca
    18841 tctttttcaa aattagtttc atcaaattca actatttcat atggtatttt tacatcttca
    18901 ggttttattg tatatttata gaaactcttt accaaactgc aatttcttct actgtataga
    18961 cttcttgttc ctgatataat tacaatatct acaccatcat aaaacatttt ttcttctacc
    19021 ttatccaata tcttagatga atagcctctc ttttcataat ctggatgagt acatactcca
    19081 cctatagctg caaccttcaa tctatttcct tgaatagata catcttgaat tagatagttt
    19141 acatcagaaa ccactttatc atcttctgat attataatca tattttctat attattttta
    19201 cttagtaaaa gaggaaattc ttccatcata gttggtttat gatttcttga tatcctaaat
    19261 acatagttta ttaattctat tactttatca aattcttcta attttgcact tcttggtctt
    19321 aattccattc atattcctcc aaatattatt taatatactt aaaactttat tatctataat
    19381 aaaacattta ttactacagt tctaattata tcttttttct ttacaatttt taattgtttt
    19441 tttcagcaaa tttttataaa atataaacct aatttctagt taaacttata aaataaccca
    19501 ttatgtataa tatattaaaa tattttctat atatttatat gactaagttc tataactaaa
    19561 ttgaaataat cactttttca agaatgttat aattttttta ttgtattctt tttgctatag
    19621 tctatgaata aattaataga aaatcttcta agttactttt aaataatgac tttatggttc
    19681 aattgtacta aaatagtata tgtaggttac aaataatcta ataaatatta aagtttggag
    19741 gtaatagata tggcagattg taattcatgt ccatcaaagg gaaattgtaa tagtcaatca
    19801 aattgttcta ttgaaaataa ccctaacaat aaatttggaa aaataattgg tgttatgagt
    19861 gggaagggtg gagttggaaa atcaactgta actgctttac ttgctaataa gctaaacaaa
    19921 atgggatata aggttggtat attagattca gatataactg gaccaagtat tcctagactt
    19981 atgggtgtaa aaaatgtaaa agcttattct gatggctctt atatttaccc tgtagaaaac
    20041 tcaaataaca taaaagtaat gtctataaat cttatgatag atgatgagaa tgaacctgtt
    20101 gtttggagag gacctttact tggaggagtt gtaaagcaat tttatactga tgtactttgg
    20161 gaagaattag actatttatt aatagatatg cctcctggta ctggagatgt tgccttaaca
    20221 gttatgcaat ctattcctat aagtggaata gttatggttt cagtacctca agatttggta
    20281 tctatgattg tatcaaaagc tgttaatatg gctaaaaaaa tgaacataaa tgtccttgga
    20341 gttattgaaa atatgagtta tatccaatgc cctgattgtt ctaaaaaaat caagttattt
    20401 gaaggagaat ctactgaaaa gtttttagat gatttagact tagagctttt aggagaactt
    20461 cctatgacta aagaaattat agatattact cataatagag ttacagaaat tagtgatgat
    20521 ttagattcaa tattgactaa tgttgttgaa aaaattaaat aaataaaaat tttataattt
    20581 tatatttatc aaaaaagagg cttatattta ttttataatc atacaaataa atataaacct
    20641 cttttatgtt tatctatgtt ttaaatacac aaaatattct tctacttcat ctccattttt
    20701 tacttttact aagtattcat tataatgagc attatatggc ttagtcattt tgcattctat
    20761 tacattttct atgtcttcta attctaaaag ttctacatcc tttaaaaatt ttctttctat
    20821 gagttccatt aatctttcca taatatatcc tcacttcccc tataattaag ataaactata
    20881 taatcctctt aatccaaagt ttacccgttt attatattat atccaatata ttacagtttc
    20941 taacataatt cataattatt ttagcaagta gagattgatt ttttaataaa tgtacctttt
    21001 ttttatcaac attttcttaa taaaaacttt tttatgtatt gtatatgtat ttaaataata
    21061 ttttttatat atttagtact gtatatttag tattttttca attatataaa gagttcctct
    21121 taatcctaca aaaggagtgt atggatatat atttacactt tttaggtttg gattacttat
    21181 ctgcatatcc aactttgaat tatgtttcat atcgatacta gcaccatctc caaataatgc
    21241 taataactca ttttctttta aatatttact tctatccagt tcattgttcc caatatacac
    21301 agatttatca ttacaatcta cattatgcaa tacattaact ctctgaacct cccatgacta
    21361 aagtcacagg gttcctgctt catagaattt tgcataataa aatatgtctt actaattctc
    21421 cacaggccat cccc
//
LOCUS       DBGJFK010000069        21391 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.069, whole genome shotgun sequence.
ACCESSION   DBGJFK010000069 DBGJFK010000000
VERSION     DBGJFK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.069"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            9..1016
                     /locus_tag="ACOIAP_002843"
     CDS             9..1016
                     /locus_tag="ACOIAP_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGZ2639722.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIYFFIFIIESLKLISINQFQLMYLMLILISSLCVIVYSYKITSLYIFKNF
                     KIGILLVFYFLFSQIIFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSF
                     LQSILFDRFGKKIGIVMVGTCWSLWHLPLQFTLYSPQTPIIGAIAHLIYGIGLSIFLG
                     YVYMKTKNIWFCSIMHVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEY
                     K"
     gene            1396..2922
                     /locus_tag="ACOIAP_002844"
     CDS             1396..2922
                     /locus_tag="ACOIAP_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGZ2639723.1"
                     /translation="MNESYWFLNSNPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYRETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMAAVLENKLADGMFISIDDPSITFRQY
                     NDGNENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKKVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            2950..3507
                     /locus_tag="ACOIAP_002845"
     CDS             2950..3507
                     /locus_tag="ACOIAP_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639724.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKLFLVIFLFMFSMGVASLWEIGEFLMDTFIGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSSI"
     gene            4029..5072
                     /locus_tag="ACOIAP_002846"
     CDS             4029..5072
                     /locus_tag="ACOIAP_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639725.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKSIDEEGVV
                     VNIDNEILTKVEVVNDDNEIQEKIIEEDWLISENTLKLDDKEAIINDKDIELCKKEVQ
                     VESEKIDLNKFEELDQNENYNLEKNVIEEKEVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHKQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKN
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYKFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDVLEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            5183..6325
                     /locus_tag="ACOIAP_002847"
     CDS             5183..6325
                     /locus_tag="ACOIAP_002847"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGZ2639726.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKIKKREVK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKNNYLQVRASHILIKTVDDKGKQVSNSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEIKSDLVSSLTSEKQSLLIQNLKEKYNVKITDKYQMKAKE"
     gene            6783..8174
                     /locus_tag="ACOIAP_002848"
     CDS             6783..8174
                     /locus_tag="ACOIAP_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HGZ2639727.1"
                     /translation="MSSTESVSKKGGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSITMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEE"
     gene            8427..10220
                     /locus_tag="ACOIAP_002849"
     CDS             8427..10220
                     /locus_tag="ACOIAP_002849"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HGZ2639728.1"
                     /translation="MTIKDRLSGLRKLMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDGIWTDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYSDVYEFVKNIDKAEKVLVDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEIELENIRNSHIKDGVAFTKFMYWLKQNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKVKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(10302..11684)
                     /locus_tag="ACOIAP_002850"
     CDS             complement(10302..11684)
                     /locus_tag="ACOIAP_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HGZ2639729.1"
                     /translation="MSVLKTQEKLKQPKDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLSWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGASISMYGYRYVFLFSSITVLIGLFFFVFGNRKFYNSLN
                     NNHSNERESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVMQTGTDSNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISLLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSS"
     gene            11942..12289
                     /locus_tag="ACOIAP_002851"
     CDS             11942..12289
                     /locus_tag="ACOIAP_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGZ2639730.1"
                     /translation="MIRKKSELQVEVKENLNGGIGNVKLENIIQNEELKGKGRLFKRV
                     SLPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            12307..13341
                     /locus_tag="ACOIAP_002852"
     CDS             12307..13341
                     /locus_tag="ACOIAP_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6398 domain-containing protein"
                     /protein_id="HGZ2639731.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKEINSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLNESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARGKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(13390..14439)
                     /locus_tag="ACOIAP_002853"
     CDS             complement(13390..14439)
                     /locus_tag="ACOIAP_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HGZ2639732.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEIGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MIGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSVGKGGTSMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            14714..16249
                     /locus_tag="ACOIAP_002854"
     CDS             14714..16249
                     /locus_tag="ACOIAP_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639733.1"
                     /translation="MRFIKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKDPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNRVSAVGVGKATIYAKCGNKEVERTFRIEARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPIERAISLSSNGNIVGL
                     REGKDRVRITCGDKSKIITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNVDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMKVESISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNNSQNSDVI
                     NVR"
     gene            complement(16396..16734)
                     /locus_tag="ACOIAP_002855"
     CDS             complement(16396..16734)
                     /locus_tag="ACOIAP_002855"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR00035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047661 - amino-acid racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HGZ2639734.1"
                     /translation="MKKVALLGTKYTMEQDFYKNIIINNGIDVLIPDEEDRIIVNNTI
                     FNELCVGIVSESSKKAFLSIIDKLGKQGAEGVILGCTETGLLIKQNDTSIPLFDTTII
                     HAIEAALSSI"
     gene            16799..17101
                     /locus_tag="ACOIAP_002856"
     CDS             16799..17101
                     /locus_tag="ACOIAP_002856"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGZ2639735.1"
                     /translation="MELGTVHPPYEQNTYIIDFIKSILNQPEIDKFLQYMSPSGTYMQ
                     KKSIAKWIERNNIYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFLELNQ"
     gene            17122..17283
                     /locus_tag="ACOIAP_002857"
     CDS             17122..17283
                     /locus_tag="ACOIAP_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639736.1"
                     /translation="MVPIPQDNNEMSIEHLESYCKNENIKGIYLIPDYHNPTTHSMSD
                     LSCKKIAKQ"
     gene            17343..17666
                     /locus_tag="ACOIAP_002858"
     CDS             17343..17666
                     /locus_tag="ACOIAP_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639737.1"
                     /translation="MFSLASDNTIYIFCTSKFLCAGLRIAFVVAPKRYIENLEDALYN
                     MNLMVSPFTAEIVHRLLYSPILDKIIKEKKDTIIEGNKVADKVLSDYNLMNWRESHLK
                     YLQKI"
     gene            17675..17809
                     /locus_tag="ACOIAP_002859"
     CDS             17675..17809
                     /locus_tag="ACOIAP_002859"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639738.1"
                     /translation="MYCAERFSVGNSTVPKAIRICITAPKDVEELEKGLNIIKSLLNS
                     "
     gene            18210..19478
                     /gene="eam"
                     /locus_tag="ACOIAP_002860"
     CDS             18210..19478
                     /gene="eam"
                     /locus_tag="ACOIAP_002860"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016869 - intramolecular aminotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006536 - glutamate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HGZ2639739.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEHIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTYIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPIYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(19571..19927)
                     /locus_tag="ACOIAP_002861"
     CDS             complement(19571..19927)
                     /locus_tag="ACOIAP_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639740.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(20078..21172)
                     /locus_tag="ACOIAP_002862"
     CDS             complement(20078..21172)
                     /locus_tag="ACOIAP_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGZ2639741.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTIMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTTALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         8510 a         2351 c         3458 g         7072 t
ORIGIN      
        1 aaaattttat gatttttaca attatttttt ataaaaaagg gaggttatgt ttgttgaatt
       61 tacaatcaaa atgggtaaac tttttaaagc caacatatgt cagtgatgaa ataaaaagaa
      121 aaaaactaca agttataata tttttttcta taacttatgg tttatcttat tcactaggtt
      181 tattagcaat atgttttaat catttaatag attcagaaat tttagctcaa tttatgatga
      241 tattaccatt atcttcagtt tctattgcaa aattttacac agagggaaga aataatgata
      301 aatataattt ttattcatca gtaatattat tttttattat ttactttttt atatttatta
      361 ttgaatcatt aaagttaata agtattaatc aatttcaatt aatgtatctt atgttaattt
      421 taataagtag tttatgtgtt attgtttatt cttataaaat aacaagttta tatattttta
      481 aaaattttaa gataggtatt ttgctagttt tttacttttt attttctcaa attatttttg
      541 gattaataat aagtgataat caatttgatt ataagaattt cttgaattat attcttcttc
      601 ctataatatc attagtatac atttatcctt ttttatgtga agagtatggt tggagatctt
      661 ttttacaaag tattttattt gatagatttg gcaaaaaaat aggtattgta atggtaggca
      721 cttgttggag tttatggcac ttacctttac aatttacact atatagtcct caaactccaa
      781 taattggagc tatagcccat ttgatatatg gtattggact ttctatattt ttaggttatg
      841 tttatatgaa aactaagaac atatggtttt gctctataat gcatgttcta attaatagct
      901 taggattaat tttcaatgat tctgaaataa ttattaatta ccatagtatt atacaaagat
      961 tgatatttat actattattt tatactcctt ttctatttac aaaagaatat aagtaagaat
     1021 tacaattaat ttatataaaa taaattttta agtaaatatt tttatagaga gattgttata
     1081 ttacatatca gaaaaatatt aaacgaacta aatcaataaa aaagttggtg gctaacaatt
     1141 tataattgtt agcacaacat catcttatgt attgaaatct aaaatattct catttttact
     1201 tagcataaat actattaatt aagaaaataa tatagaaatt ataaatatat ataagtttag
     1261 tctggtgtat aaaacaagaa aactaagtga tttttaattt agctttttat taagcttatt
     1321 ttttatacta tttataataa ataaactcca tgatgggaaa actattacta tttaatatgt
     1381 aaaggagtat tttaaatgaa cgaatcatat tggtttttaa actcaaatcc aaaagaatat
     1441 aacaaattag gtgaaaatat aaaaacagat tgtcttatag taggtggtgg aataactgga
     1501 ttgacaactg catatttatt agcaaaagaa ggtaaaaaag tagtgcttgt tgaggctgat
     1561 aaaataggat atggaacttc tggaaggaat actggtaagg taacttgtca gcatgacata
     1621 ttttactcta agatagagaa aaaatatgga ttagataaag caaaatcata ttataatgca
     1681 aataatgaag ctttaaattt agttgaacaa ataatagaag aaaataatat aaaatgtgat
     1741 tttaaaaggg aaacttcttt tgtatttaca gaaaaagagg atactataaa gaatattaaa
     1801 gatgaatatc gtacatgtaa aaaaatagga ataaattgtg agtatcgtga aactatagaa
     1861 aatattccat tagatataaa gggggctatt agttttacta atcaaggtca atttaatcca
     1921 aagaagtata ttgatggatt ggcaaaagca gcagtaaatt tagggctaaa aatatatgaa
     1981 aatacaccag tagtagacct tgagaaaggc aaaatatgta gggttaaaac aagagaggat
     2041 aatataatag aagctgagaa tgttataatt tcatcccata gtccatggta tgatggattg
     2101 aatttttatt ttgcaaaaga atatgcagag cgtgcttatt taatggctgc agttttggaa
     2161 aataaattag cagatggtat gtttataagt atagatgacc catcaataac ttttagacaa
     2221 tataatgatg gaaatgaaaa tttactgatt tttggaggag gagaccataa agtcggtcag
     2281 ggaggaactg agaaagaaat atttgatgat ttagagcatt atgggaaaaa agtctttaag
     2341 gtaaaagatt ttaaggggaa atggtctgct caagataata tgagttttga caatgttcct
     2401 tatattggtt atatcaacaa aagagaagac aatatttatg tagctacagg gttctctaaa
     2461 tgggggatta ctaatggaac tgctgctgga ataataataa aagatttgat aataaataat
     2521 aattctgatt ataaagatac ttttaatcca tccagattag gtagctactt ttcaaaagat
     2581 tttataaagg aaaatgcaaa cgtagcaata aattatgtaa gtggaaaatt aaaaataggt
     2641 agtggagata tgcctaaaaa taatggagaa ggaaagattg ttaatattga tggaaaaaga
     2701 tatggtgtat ataaggatga taatggagat ttttatattg tagacacgac atgtactcat
     2761 ttaggatgtg aacttaattt taacagtgaa gaaaaaacat gggactgtcc atgtcatggt
     2821 tctagatttg actataaggg aaatatactt gaaggaccag ctcttaagcc attaaaactt
     2881 tatggacatg gtgataatga tgttaatcct aagttattat aaaattattt ttaggaaggt
     2941 aaagtgtata tgaataaact tttaaagcca ataactatac tattgtatat agtttatatt
     3001 ttatctgctg tattttttgt agcaaacaaa gaatatggaa gtctaggtct agtagcaatt
     3061 agtttagttg gtactttcat tttgagtttt ataaataagc aaactgaaag attattgagt
     3121 aaagaattat atataatgct tgctttattt ataatgtttt catcattatt aggtacttgt
     3181 tttaattttt atgatataaa ttattatgat gattttttgc atttatggtc aggtataata
     3241 tcttgtattg tggctttttc tataattaaa tacttttata cacaaagaga gataagtaaa
     3301 atgagtaaat tgtttttagt tatatttcta tttatgttta gtatgggagt agcgagttta
     3361 tgggaaatag gtgaattttt aatggacact tttattggga ctactacaca ggctggagga
     3421 ttagaagata ctatgattga tatggtagat gctttaatag gtacaattat aactattcct
     3481 tttatagtaa aaaaatctag tatatagttt taaatttttt atattagtta taatggattt
     3541 aattaatcat gttgagtttc aaggtctata tgattaatta aatccatttt tgttatttat
     3601 aattattatt gaatatattt ttacatatga gatatacggt gatagataga aattgttgga
     3661 ttatgtaaat aattaatata taataccatt atgggcaata aatacaaatc aaatgataat
     3721 atagtctatt tatgtaaatg ttatattgta tcctaagtat aatagtaagt tttttgataa
     3781 tggtgtagaa agtaaaaatc tactagtcta aattgatgta tggattagtt taggaacagt
     3841 aattgcatat cttaaatttg atgtcatgtt gagctactag aaataggtca tctttttcac
     3901 ttgaatatct tttctttaaa catggggagt atcatatcaa aaacatatga aaattaagtg
     3961 atttataaga acagtaatat tttatatgat agtatagaat agtaataaag tattaggagg
     4021 aacattgagt gttaaaaaag tggtttggta ttgtgaaaaa aagacaaaaa agtgagtcag
     4081 taaaagaaga aggtgaagta atattaaaaa atgaaaaaat attatctgaa gaaaagtcga
     4141 tagatgaaga aggagttgtg gttaatattg ataatgaaat attaactaaa gtagaagtag
     4201 taaatgatga taatgaaata caagaaaaaa taatagaaga agattggtta attagtgaga
     4261 ataccttaaa attagatgat aaagaagcaa ttattaatga taaagacata gaattatgta
     4321 aaaaagaagt tcaagttgaa agtgaaaaaa tagatttaaa taagtttgaa gaacttgacc
     4381 aaaatgaaaa ttataatcta gaaaaaaatg ttattgaaga aaaagaagta agtgaatgtt
     4441 tgacagaaga agatttagag tacataaaag aaattaaaat aaaaagagga aaaagtataa
     4501 aagctataaa cttgtatact aaagaagagt gggtttttga cactcataaa cagtgtagta
     4561 aaaaactcaa agttccatta gggtatatac gagaaaattt aaaatatgga tatatggatt
     4621 actttggaga tgcaataaat tatttaagtg aagtattaaa tatagatgaa tactgcaaaa
     4681 atgaatggag ctatctcgat aatagcaaat ctccatctga gatatttaat attctaaaca
     4741 ataaaatatt tagcataagg ctttctaatg aaaaaagaaa tgaaattttg acaaatgata
     4801 aaattgaagc attaaaaatg aattataaat ttgaatgtat tgatgaagaa tatgatgaat
     4861 attttaaaaa atataagtct ataatcaaaa gaggtggaaa gaaaaaagtt gaattagtaa
     4921 ataaaaaagg tgacgtttta gaaatattta agtctttaga agaatgtgcc atttatttgc
     4981 aaaaggaaaa gaatgaagtt atacaaatgt taaaatatgg agatacaaaa gtaggaagga
     5041 actttataag gtatagtttg agaagtattt aatttcattt taaattcata agagtttcat
     5101 ttctgattca cacatttaat attattttaa tgtaaaataa taaaggtgaa gtattgcaca
     5161 attaaaatta aggagggtat taatgtctga agaaaaaaat ccaaaagaaa atacattaga
     5221 tgaatctaaa aattcagata acgtaaattc taaaaaagat gatgtgtcag atgaaaaaaa
     5281 tactgataac aaaattaaaa aaagggaagt aaagctaaac aacaaaacac ttaaagctat
     5341 tgtagcaatt gttgcagtag gagctatatg tttaggtgga ggctatgttt ttggcaaaga
     5401 agctggaaga aaattgcctg ctacttcaaa acactataat agcagtgagg tagtagctac
     5461 tattggggat aaaaaaataa caggtgaaat gttaagaaag agaatggagc cattatttta
     5521 tttaaatgca aaaactacta tgactgatga tgaaatacgt tcatatgaat caaatatgat
     5581 tgaaactatg attacatctg atatattatc ctctgaagca gcaaaagaga aaataagtat
     5641 aactaatgac caactagatg ctcagtataa taatttaatg agtagtatag aatcagcaat
     5701 gggaatgact aaagaagagt ttttaaaaca gtttgatttg actgaaaaat atataaaaga
     5761 tgatatgaaa aaagaactgg tagcatcaaa atacttaaat gaaaaatcaa aagttactga
     5821 taaagaagca gagaactatt acaataaaaa caagaacaat tatttacaag ttagagcttc
     5881 acatatttta ataaaaactg ttgatgataa aggtaaacaa gttagtaata gtaaaaaagc
     5941 tgaacttaag aaagaagctg aagaaatact taaaaaagcc caagctgggg aagattttgc
     6001 tactctagct aaaaaatact ctgaagatag tagtgcagaa tcaggcggag atttaggttt
     6061 ctttggtaaa ggtcagatgg tggaatcttt tgaaaaagca gcatttgcat tgaagaaggg
     6121 agaagtatct aacaaacttg tagaaagtga ttatggatat catataatta agaaaactga
     6181 tgaaaaatat caaccatttg aagagataaa atcagattta gtaagcagtt taacatcaga
     6241 aaaacaaagc ctacttatac aaaatctaaa agaaaaatat aatgttaaaa tcacagataa
     6301 atatcaaatg aaagctaaag aatagataaa gtcaatttat aaaaaaaaag aaaaatttac
     6361 tgtatggata aaagctattt ttgctctcaa tatagagagt ctaaaatagc ttttattatt
     6421 tttgaataaa atctatttac atatatgaag tgacaaagaa ataacatgca aaaaaatatt
     6481 aacaagaaat atccttaatt tgaattattt tagataaaac atttataaaa atgaaaaaat
     6541 aaacaaaaaa taattgaaga tttgagctgt tgtttaaata tatatatata ttaagatttt
     6601 ctactgaaaa tactgaaaaa ataatatttt tcataatttt aaaaataata ataaaaaaat
     6661 gaaaatacag gcgataatct attgagtaaa gatagaaaag atgatattat aagtatgtgc
     6721 taaaatggtt aaagcaatct taatattaaa tttaactata aaacaaaagg gggcgttttt
     6781 ttatgtcaag tacagaaagc gtatctaaaa aaggtggtca tcctaagagt ttttggctta
     6841 tttgcatgac aattttatgg gaaagattta gttattatgg tttaacagct ttattggtat
     6901 tattttttac agcaagtgta gctcaaggtg gattaggtct ttctactcaa gaagcaacat
     6961 ctatgtttgg tttatttaca ggtcttatat atcttacacc attagtcggt ggttggctag
     7021 cagataaagt tttaggtcaa caaaaatgta tttctatagg tgcactttta atagcaatag
     7081 gagatttcgt actatttgct tcatctacat ctattaccat ggtttgggta ggtctatcaa
     7141 taattatttt aggaaatggt ttttttaaat caagttgttc aaatatagtt ggggatatat
     7201 atcctaaaac tgatgtgtca agaaaagatg cagcatacag tttattctat atggcagtaa
     7261 atgtaggagc atttatagct ccaataatat gtggattact ttctgataat gtgtttgcag
     7321 taagaggagc aagtggagat atagtatctt atggatataa gatggcgttt ttaatttgtg
     7381 gtataggcat gatgttaggt atgattatat ttacacttct tgcaccaaaa ttattaaatg
     7441 aagtgggaaa atatcctgtg actaaaggca ataaaggtga aaaaattgag tatggaccac
     7501 ttactaagtt ggagaaaaat agaataatag caatggttat tttattttta tttgtggtct
     7561 tattctggac agcatactat caaacacaaa gttcttttat gatttatgta agagacaatg
     7621 taaatagaac tctatttgga tttgaaatgc cagtagcatg gcttacatca ctaaatgcta
     7681 tattatgtgt ggctttatgt ccagtattag ctaccctatg ggttaaatta tctcatacca
     7741 aaagaggtga tttctctatt ccagttaaaa tgggattagg aatgataata atgggtgttg
     7801 ggtttatagt tatggtattt gctacattag ctaatggtcc agatggaatg gtaaaggcta
     7861 gtatattgtt tatagtattg acttatatat ttacaacagt aggtgaatta ttcttatctc
     7921 ctataggact tgcaatgttc aataaattag ctccagctaa gtatgctacg ttatctatgg
     7981 gagcatggta tctaacaagt ttttttgcaa gtttattatc aggaaagatt gctggtttta
     8041 cagctacact tggtttttta cagatatttg gaggaatagc aacagtttta ataatatttg
     8101 gtttaatatt attgggaata agaaatgtat taacgagact aatggctatg gatttactaa
     8161 caaaagaaga ataattcatg acgaattatt gtaaatagat gaattacttt aagtaaagga
     8221 aattacattt aaatataaaa ttaaatgtaa tttcctcttt gattatgaaa aaaagcttta
     8281 cacaaataga tattataatt aaaattataa ttgtgataat tagagtgtat aagatttata
     8341 taaattatat aaaaaatatt tatgtaataa actttacata cttatatatt tagttattca
     8401 aactattatt tttaggaggt cttgttgtga ctataaaaga tagattaagt ggattaagaa
     8461 aacttatgga agaaaaaaat atagacgcct atatgattcc atcttctgat aatcaccaaa
     8521 gtgaatatgt aggagattac ttcaagtcaa gagaatttat atcagggttt aatggttcag
     8581 cggggacagt tattgtgact aaagacgaag ctggattatg gacagatgga agatatttta
     8641 tacaggcaga gtctcaatta gaaggaagta caataaaatt attcaaaatg gggcaagaag
     8701 gttgcccaac tacagatgaa tatttataca aaaatattcc tgaaggagga actttaggat
     8761 ttgatggtag agttatatct gctagagaag gagctacatt agctgaaaag ttatctaaaa
     8821 aaggtataaa gatagaatat caatatgatt taatagatgg tatatggaca gatagacctg
     8881 ctttatcaga tagtaaagca tttttattgg atgttaaata ctgtggagaa agttttagct
     8941 caaaattagc tagactaaga gaaaaaatga gtgagaaagg tacttctact catgtaataa
     9001 ctactcttga tgatatagca tggttattca atataagagg tggagatgtt aaatataatc
     9061 cagttgtgct ttcttatgcg gtgataacct taaaagaagt ttatctattt gttgatgaaa
     9121 gtaagttaaa tgaagaaata ttaaatgaac tagctaaaga aaatgttcaa ataaagccat
     9181 atagtgatgt atatgaattt gtaaaaaata tagacaaagc tgaaaaagtt ttagtagatg
     9241 gaactaagct tagttataca atttacaata atataccttg tgaagttgag aaagttgatg
     9301 agtttaatcc agtaatgttt tttaaagctc aaaaaaatga gatagaatta gaaaatataa
     9361 gaaattcaca tataaaagat ggtgtagctt tcactaaatt tatgtactgg ttaaagcaaa
     9421 atgtaggaaa gatggaaatc actgaaataa gtgctactca aaaactagag gacttaagaa
     9481 gagagcaaga aggtttcttt gagccaagtt tcaatacaat tgctgcatat aaagaacatg
     9541 ctgcaatgat gcattatagt gcaactccag agtcaaatta taaattagag gcagaaggat
     9601 tatttttagt agattcaggt gggcaatatt atgatggaac tactgatata actaggacta
     9661 cagttttagg acctataagt gatgaattaa aactacactt tacttctgta gcaagaggaa
     9721 tgataaatct ttctaaagtt aaattcttgc atggttgtag aggatataac ttagatatat
     9781 tatctagaag ttgcatgtgg aatatgggaa ttgattatca atgtggaact ggacatggta
     9841 taggatttgt attaaatgtt cacgaagctc caaatggatt tagatggaga gtagtacctg
     9901 aaagatttga tagtgcagtt cttgaagaag gaatggtaac tactaacgaa ccaggtatat
     9961 atatagaagg ttcccatggt ataagaacag agaatgaaat cgtagttaga aaagctgaaa
    10021 aaaatttcta tggtcaattt atggaatttg aggttgttac attagctcct attgacttag
    10081 atggtatagt accagaatta atgaataagg atgaaaagga ttatttaaac tggtatcata
    10141 agttagttta tgataaaata tcacctttct taactgatga agaaagagaa tggttaaaag
    10201 tttatactag agctatatag tttgtactag atacaataaa aaatcgaggt attataatac
    10261 ctcgattttt tattgtatct tttattaatt ttgaaaaatt tttaacttga taattctact
    10321 aactttttat tcattataag tagtataatt ccaaatatca ataaaaatga tggtatcact
    10381 atgaatactt gtaacatacc aagttggtct ataatagctt gagtataacc agataattta
    10441 tttgctgcaa atttacctaa aaaccaaaca cccattagta atgaaatata cttttcaggc
    10501 gaaagtttat ttaccatacc atatccgact ggagaaaagc aaatttctcc tatactttgg
    10561 aatgttaaaa acccaactac ccaaaataca cttgctttat gaattgaatt agagtccgta
    10621 cctgtttgca taactgctac tatcataaat aaaaatgcta tagctaatag tataaaacct
    10681 aagctcattt ttttgggtac acttaaatcg ccttttttag tttgagataa ttttacccat
    10741 actagagcag agataggtcc aagaataaca caaaggagac cattatatga atctatccat
    10801 gaagtaggaa tttgaaaatt gccaacagta agatttatat gctcttttgt atagagtgca
    10861 atagacatag aggcttggtt atatgctatc caaaaaaata ctgtgaaaaa agctaatacc
    10921 aatattacta ttattctttt tttctcaatc aaagttaatg gtcttgaagc gagcattttc
    10981 ttatattcta gtgattttct tatagattct ctctcattac tatggttatt atttaaagaa
    11041 ttataaaact ttctgtttcc aaatacaaag aagaataaac ctattagaac cgtaattgat
    11101 gaaaataaga atacatatct gtatccatac atacttatag aggctccact tttcatagca
    11161 aaccattcat tagcaactaa accacatatt aaaggaccaa ataaagtacc tagattagta
    11221 gccatatatg taatagagaa agctccatct tttcttgggt catcattggt atataagttt
    11281 ccaaccatgg tatgtaagtt tcctttataa aaacctattc ctaatccaga taaaaatatc
    11341 atgatgttta tatccatctt actatttgct atgtatccta gaaaataacc aattgaaacc
    11401 attagcattc caagtatgat acagtttttg ggacctagaa atctatcact gacccatcca
    11461 ccgataactg gagagaaata agtccatgat aaaaaagatg caagcattga tgcggattct
    11521 gctggtgtta accctaaacc acctttggag acttgttcag ctaaaaataa taataatacc
    11581 aatttcatgc catagtatgc aagtcctaca aaggtaaata ttgaacagca gaaatataaa
    11641 tctttaggtt gtttaagttt ttcttgcgtt tttaaaactg acatatgtcg agaacctcca
    11701 gataaatagt ttaacaaaat tttaccatac tatatgagta tatgtttttt tcatagagac
    11761 gtcaacttat gagataattt aattaagtcg aaatatatgt aaaaatagta tcatttttgt
    11821 gtattcaata atattttttt atgataatat atgttattat tatattaaaa tacaaacata
    11881 tttatggaaa ggatatgcca atttagtagt tagattgatt gtttggcagg tgggatgagc
    11941 tatgataaga aagaaatctg aattacaagt agaagtaaaa gaaaatttaa atggtggtat
    12001 aggaaatgtt aagcttgaaa acataataca aaatgaagag cttaaaggaa aaggaagact
    12061 atttaaaagg gtatctttac cagtaggaag ttcaattggt gtgcatgacc acacaacaga
    12121 ttttgaagta tattatatac taaagggaaa aggcaaagta tttgataatg gggaatttgt
    12181 agaagtaaat gagggtgatg tagtgtatac agctgatggc gaaaagcatt ctatagaaaa
    12241 tataggagaa gaagatcttg agtttgtagc actagtttta tatatgtaaa atatggagga
    12301 ggagtcatga caggcaagat agaagaaatt aaggacaaga taaatagatt ttgcaactcc
    12361 aatttaaatc aagaatacaa ggatataagc tttaaaattt tgcaaaacct tttagataat
    12421 aataaagaga taattcattc ttctagagct gatatatggt cttcagctat actaaatata
    12481 gttttagaac aaaatctttt atacaataag aagcatccac tacatataac aaaaaaagag
    12541 ttttcaaaac aaataggtgt ttctttaaat actataaata ataaatcatc tttaataaag
    12601 gatgtttgta gtattgactt tttaaatcaa gatactatag ctatttctaa tgtagaattt
    12661 tgggtaaaag agataaattc caaatcaaag tctgtagatt tagatttaga aaagaagaaa
    12721 atactatata aaagatatat taagctatca caagatgcaa atagtgatat tgaatcaatt
    12781 agatatatgg aggaagctgt aaatataggt aaaagtatga ttactaaaga agataaagaa
    12841 cttggatttt ggaaaggttt atctaccaga gcctatatga tagcacttga atcccttgct
    12901 aggaagttag aaagtattaa taatctaaat gaatccaaaa aagtattgga atatttaata
    12961 gaaattaatc ctagtgatga gcagggaata agatataaat tattaaatgt attaattaga
    13021 ttaaacgata gaacctcaat aaataaatta tttgaacttt ataaagaaga aaaatctgct
    13081 acatggatgt acagtaaagc tctttattac tttaaaaata aaagtatgtt tttggcaaat
    13141 gattctatta aggttgctag aggtaaaaat aagtatgttg gattatattt gttagattgg
    13201 cgaaatgctt ttggtagaga atttgttaca gaagaagaaa aggcagaagc tgtatattac
    13261 tatgatgaaa acatagtgat ttggaatgaa gttaaaggtt ctatggattg gctattaaaa
    13321 aaaatgttgg aattttcata aaaaaaacta ctccttactt ttatataagt aaaaggagta
    13381 gtttttaatt tacacatcta gttttaaatc ttcaggtttt attagacctt tttttctcat
    13441 aaattctgaa atcaacaaag ttacaatagc aggaagtata aaattaagta aaagtatacc
    13501 aacccacata gatgtacctc cctttccaac actttgcata gcagtcactg ttccaaattg
    13561 tccaaccaat ccacaagtac ccataccaga gccgatagga atattctcca ttttgaatat
    13621 tgttgtagat aatggtccaa gtaatattga agctacagta ggtggtatcc aaattttcca
    13681 attttttatt atattaggta cttgtaacat agatgtacca agaccttgtg ccacaaggcc
    13741 accaactcca ttttctctaa agctcataac agcaaagcct atcatttgac aacaacaacc
    13801 tacagttgct gccccaccag caagaccacc caaacttaac atcatacaaa tagctgcact
    13861 acttataggt aatgtaagag ctattccgac aagtgcagag actaaagctc ccattattat
    13921 aggttgcata gttgtagctt gcattattat atttccaaat gaagtcataa aagcagaaac
    13981 agctggacca ataagctcag ctacaagtac tccaattagt attgttacag caggtgtaac
    14041 cagtatatct atttttgttt cttttgaaac taattttcca atctctacag caaaaagtgt
    14101 agcaacaaat gctccaacag gtcctcctaa ttcattacca caagctccaa caagtgcaca
    14161 agaaaatagt acaagtgggg gtgcttgaag tccatatgca atagccactg ctatagctgg
    14221 accggtaacc tgtttagcaa gagggcttat aacctcagta aaaagagaaa tattgaaatt
    14281 atctcctaat gtattaaaaa ttgttccaat taaaagggaa gaaaaaagac cgagtgccat
    14341 ataacttagt gcatcaataa gatacctttg aacagaaatt tcaatgtttt ttcttttagc
    14401 aaatgatttg aaatttcttt ttttataatt gatttccaat ttaaaatcct cctcatataa
    14461 tataagtata atttcttttt aattaattat ataacttttc agctgacaag acaaatgtta
    14521 tttcactaaa attagactat tgcaatagta agaaattaac attaatttta gttttaaatt
    14581 ttaaatttat ggtttataat tagtataggg atattctgaa atataataat tttccagttt
    14641 atcccaatat ttaacttagg tagattgctt acaaaacaaa tgattatata ttaagctaaa
    14701 aggaagtgga tagatgagat ttataaaaaa taagaaatac agaaaaattg ctataattat
    14761 atctattcct atattgcttg ttgcgcagta ctaccttttt aaatttggaa tacttagacc
    14821 aatggtaaag ggagtagaaa ttgaaattgt agatggggaa tatgttaaag atatagataa
    14881 gtatgtagta aaattaaatg aaacagttac tttatccact ggtgaatata ttaaggttcc
    14941 ttcgtatgct aaagatccaa atatttggtt taatgtattg gataattcag gaactttaaa
    15001 aatagatgga aataaaatga cagcattaaa ggttgggtat tcttctgtgg gtatcatgaa
    15061 aaattcaaga gtattaaaaa aggctactat aaaagtagta gacccagagg tagagtcact
    15121 agatatggag attaatggag atttaaaaca tgttggtgat agtgctacta tagaaagcac
    15181 aatagaggtt gattatgaca agtttaaaaa atcatataag ccagtttata agagtagtaa
    15241 tgaaaatatt ttaaaaatca aaggaaatag agtaagtgca gttggagttg gaaaggctac
    15301 aatatatgct aagtgtggaa ataaagaagt tgagagaaca tttaggattg aagctagagt
    15361 tgctgaaata aatatggatg atataaaaat agaagttgac caaaatgaaa aattgaaacc
    15421 agatataata acttctccac ctggtttaga accaccaaaa atatattatg agttagtaga
    15481 ttcaaaatta cctatagaaa gagcaataag tttaagtagt aatggaaata ttgtagggct
    15541 tagagaaggc aaagataggg taagaataac ttgtggagat aaatctaaaa taataacagt
    15601 aacagtagtc aaagaaacta taacgaatga ctatatacaa aatttggttg gctcacataa
    15661 aatagtaaat aataaagtta ttattaaact tgaatgggat tatatgaaag atgtctttga
    15721 ttatgatata tatcttaaag ataaattgtc aggagaatca tttaagaaaa ttaaatctat
    15781 aactataaat gaaagtgatt taggtaagtc taacaaagta tatgcaacta tagaagtaga
    15841 tatgaagggg aatcaaaacg tagattttga tatctatgtc atagggaaaa aggattcaga
    15901 tacaactaag ccaagtaatg taataaatat tactaatggg aatggaaatt caaataatga
    15961 taataacatt aaagacatga aagtagaaag tatatcagct aatgttgata gagataataa
    16021 tgttattaga gtcaactgga gtagtatatc tcataaggat tgtacttaca gcatatatgt
    16081 aaaaaataat actaatggag atggagaatt tactctatat caaagtgata tacaggggaa
    16141 tgagcatact ataagtattc ctgaaggaga cttaaatcta gatatttatg ttgttgcaaa
    16201 ttataatggg aataactctc aaaatagtga tgttataaat gtaagataga tttgtataca
    16261 aatgagtatt aagtttattg aaaaattaaa ttaagaaaaa ggatagtgtg atagcaatca
    16321 tactatcctt ttttgttaaa atatagaggt ttcaaatttt tagttaaaaa aattttttta
    16381 ttaattgata ttgtattaaa ttgaacttag tgctgcttct attgcatgta ttattgttgt
    16441 atcaaatagt ggaatagaag tatcattttg tttaattaaa agacctgttt ctgtacaacc
    16501 taatataaca ccctctgcac cttgcttgcc aagcttatct ataatagata agaaagcttt
    16561 ctttgaagat tcagatacaa ttccaacaca aagttcatta aatattgtat tatttactat
    16621 tatacggtct tcttcatctg gaattaaaac atcaattcca ttattaataa ttatgttttt
    16681 ataaaaatct tgttccattg tatatttagt acctaataaa gctacttttt ttatttcttt
    16741 ttcctttgat gtaaatgtaa gtaatacatt attatatcaa acagaatcaa aagacataat
    16801 tgaactagga acagttcatc ctccatatga gcaaaataca tatattattg attttattaa
    16861 aagtatacta aatcaaccag aaatagataa atttttacaa tatatgtctc catctggtac
    16921 gtacatgcaa aaaaaatcaa ttgcaaaatg gatagagaga aataatatat acactagtga
    16981 agaaaatatc ttattatcta caggagggca aaatgctata tgtgcaacct tactaggatt
    17041 atttaaagcg ggtgatagga ttgctacaga ttctttgagt tttctggaat taaatcaata
    17101 gctaaaataa taggtattca attggttcca attcctcaag ataataatga aatgtcgatt
    17161 gaacatcttg aaagttattg taaaaatgaa aatataaaag gcatatatct tataccagat
    17221 tatcataatc caacgacaca ttctatgtct gatttatctt gtaaaaagat agcaaaacaa
    17281 taaatataat aatcattgaa gatgccataa acagtatttt tagagatagt acacaaactc
    17341 ctatgttttc tttggccagt gataatacta tatatatttt ttgtacatct aagtttttat
    17401 gtgctggtct tagaatagca tttgtagttg ccccaaaacg atatatagaa aacttagaag
    17461 atgcactata taatatgaat ctaatggttt ctccatttac ggcagaaata gtacaccgtt
    17521 tactatattc tcctatttta gataagatta taaaagagaa aaaagataca attatagaag
    17581 gaaataaagt tgctgataaa gttttgtcag attataattt gatgaattgg agggaaagtc
    17641 atttgaaata tctgcaaaaa atctaggtgt tcaagtgtat tgtgcagaac gattttcagt
    17701 aggcaactct acagtaccaa aagcaatccg tatttgcata acagctccaa aagatgtaga
    17761 agaattagaa aaagggctca atataataaa gtcacttctt aatagctaaa tttattttac
    17821 tatgatttaa ttaaataaat aaaaaggcgg agaaatttat tataataaac ctccgctttt
    17881 attatttaat gaaatacttt actttctatt aaaaatttaa ttttaataat cttgaaaaaa
    17941 taatcgtttt atgataaaat aattcttaaa aatagaaaaa attaatcatt tgttaaaaaa
    18001 aatgcataat atgttgtaat ttattgacga aagtagaaaa atattcataa atgtgcaaaa
    18061 taatagaaaa aatgcaaaaa taagttcaat ttcatttgtt ataaaatcta tatggcaaaa
    18121 tcaaatttgc ctatcagaat gatataaaca catcagaaag gaggaggcta tcaaacaata
    18181 taagtagtta actttgatag caaaaaatta tgaatgaaca aactagaata tccttagaga
    18241 gagctgctga actaaaatca aaaattgatg attatattca ggctagaaaa acgattaaca
    18301 gaggtcttga aaaagaagaa gagataaata aacgaaaaca gaaaatattg agtatattaa
    18361 atggaactga agaggattgg aacaactaca aatggcaatt atcaaataga ataacagatg
    18421 tagatacttt atcaaagatt ataactctaa ctaaaaaaga aaaagaacat ataaaagagg
    18481 ttggtactca atttagatgg gcaatatctc catattattt aagccttata gacccagaag
    18541 atatatgtga cccaataaaa ttattgtcta taccaacata tatagagtta gaagatgagc
    18601 aagaagattt ggacccaatg ggagaagagt atacaaatcc agcaggatgt ataactagaa
    18661 gatacccaga tagattaata ataaatgtaa caaatgagtg tgctatgtat tgtagacact
    18721 gtcaaagaag aagaaatatt ggacaacaag attctcataa gtcaaaagct attatccaag
    18781 aatctataga ttatatcaga gaaaatgaag aaataagaga tgtactagta actggaggag
    18841 atgctcttac attaaaagat gattatttag agtggattct tagccaactt aaagagatac
    18901 cgcatgttga ttatgttaga ttaggtacta gaactcttgt tacaatgcca caaagaatta
    18961 cagatgaatt ttgcaatatg ctaaaaaaat atcatcctat atatataaac actcatttta
    19021 atcatccaat ggaaataact aaggagtcta aagaagcttg tgaaaagtta gcaaatgcag
    19081 gagttccatt aggaaatcag gcagtattat taaatggaat aaataatgat aaatttgtaa
    19141 tgagatgttt aaatcaagaa ttactaaaaa taagagtaaa accttattat atattccaaa
    19201 gtaaacatgt aaagggaaca aaacatttca atacatcagt agatgatggt cttgaaatca
    19261 tggagtattt aagaggatat acatcaggaa tggctatacc aacatatata gtaaatgctc
    19321 caaaaggagg aggaaaaact cctttgcttc cacaatacct tgtatcaaaa ggaacagatt
    19381 atgttatgct tagaacatgg gaaggaaaag ttataaaaat ggaagatgaa cctgctgtag
    19441 atataaagaa acttataaaa gaacaagcac aggattaaaa cagtatttaa attctataaa
    19501 aagaaacaac tttaaaataa aaagaaaatg gatgctaaat ttatatcaat ttgcatccat
    19561 tttttattag ttatttatta ttttgttgtt gattaactaa ttcaagatat ccacttgggt
    19621 ggaagtaata tatctcagaa gtattttcat ttacaaagta accaatatcg ccatctgcat
    19681 ctggtaaaaa tacataacca ttaagatttt tagcttttaa tgcttcaaaa tcactagcat
    19741 ttccttgata tatgtaatca acttcattgt tgtattttac taaaagttct ttagcttgct
    19801 cttgagtcaa tttagtattt tggcttacag gaacattctt ttgagaatct gcgtaagaag
    19861 attcatttac tggtgcagtt aataacaaac aagataaaac taataaagat ataagtgctt
    19921 ttttcatact aaaaccctct ttcatgttta attatataag attcattact taataatatt
    19981 gtatgtttcc tataattaaa tattaccatt aaagagaata atattacagt tacacagctg
    20041 taacttttga ttacaaaatc gtaattaaat tgtattttta ttccatttgt attttatcat
    20101 gtctacgatt tacaaactca caaaaatata tttttataac gcccataaca ggagcagata
    20161 gaatcatgcc tggtatacca aagaatcctc cgccaacagt aacggctaag attgtaaaga
    20221 atgggctaag acctagttgt ccacctacga tttttggctc tataaatgta acttctactt
    20281 gttgaattat tattaagtaa attaaagaag ttaaagcagt tgttggattg gagaataaat
    20341 taattattac aactggtgcc atacctatta ctggaccaaa atatggaacc atattcatga
    20401 cacccataat tgtaccaaat aacagtgcat attcagattt taaaaagtaa agaccaattc
    20461 cagaaagtac tccaactata aaagaatcta aaatcttacc tgtaaaatat ttaccaatat
    20521 ttaaatttaa gctttgacat agttctatta taaagtctcc atatttttta cctaaagaaa
    20581 tataaactac tttctttgta aatagtaaga atttttcttt ttctaataat atatagaaac
    20641 aaattataaa acctaaaaga aattgtacta taaactttcc aaccgagaat gtagtgctaa
    20701 atattccgcc aagtgaacca ataagtaagt tactaaattt aggcattaca ctcataattt
    20761 tgtcaccata ttcttttaat gtattagggt caactgattg taaactcttg cctaagtcaa
    20821 ataaaaactg ttctgtttta tctatgtatg taggaatttg agcaactaaa tcagctaaac
    20881 tatttactat ggatggaact gtaaataata taaaggaaat tagtataact atgagtacac
    20941 cataagtaag aagtaatgaa tatattctct taaaatttaa tttactttct aagaatttta
    21001 ctagtgggtt gaatatatat gctaatacaa atgctattat aaatggtgtt agtagtgaca
    21061 ttaataaact tatcactcca aaaaaatatt tgtaattatc aataacttta atcaagatat
    21121 atgaaacaac tacagtgagt acaatattta gataaatttt tttatcttgc aaaataacac
    21181 aacctttctt atatttatta aatttagata tacttaaatc taagttaaag ttaatattta
    21241 tagcttatta tacaataaaa agcagtatta atatagtctg attaatatga aattataaat
    21301 acgttaaaac tttatgttta tggctaaaat aataaaaatt atttatatta tgttcatata
    21361 taatctaaaa taaaaaataa tgcctttaat t
//
LOCUS       DBGJFK010000070        21249 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.070, whole genome shotgun sequence.
ACCESSION   DBGJFK010000070 DBGJFK010000000
VERSION     DBGJFK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21249
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.070"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            156..2237
                     /locus_tag="ACOIAP_002863"
     CDS             156..2237
                     /locus_tag="ACOIAP_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2639742.1"
                     /translation="MDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKINDM
                     LKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKAERLLYMYLMLFIN
                     MEDISINHFINSIKVSRSTVNLDFKDLIPNLEKKGIEVKNNRINGYYLVGNEMEIRRV
                     LIKSIIETLSNEKSSRVFDIFIKEYNLDSFEEDKEIILKLIKKYEITFVEDRLIEFIY
                     IFIFLKARMYSTRIVTHENVDIPNIAVMSSMKEYKFAKELLETYESEDKIKSHNIMYI
                     SAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFRPA
                     YYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHFAT
                     LFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENMSEP
                     VDIVFTTNYNTEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEVMN
                     IIKKYANVTSESILSSELLTYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNWED
                     AIRQSASVLVENNKTTEGYVEAMINSAKASGPYIVITKHVALPHARPEAGSKEIAIGI
                     ATLDSPIEFGNDENDPVKYVFCLSAIDNNSHLRAMSELVELLEEEEFFKVLDSAKEPK
                     EIIDYIKTHEL"
     gene            2252..2539
                     /locus_tag="ACOIAP_002864"
     CDS             2252..2539
                     /locus_tag="ACOIAP_002864"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639743.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIVKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKHLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            2566..3837
                     /locus_tag="ACOIAP_002865"
     CDS             2566..3837
                     /locus_tag="ACOIAP_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGZ2639744.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFITAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNSSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            3894..4493
                     /locus_tag="ACOIAP_002866"
     CDS             3894..4493
                     /locus_tag="ACOIAP_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGZ2639745.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACNLIFEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTPAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKGTLETLKINGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIVLQSLSVALQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            4498..5382
                     /gene="dapA"
                     /locus_tag="ACOIAP_002867"
     CDS             4498..5382
                     /gene="dapA"
                     /locus_tag="ACOIAP_002867"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGZ2639746.1"
                     /translation="MKYKGIICAMITPFDENQNINSRATCQLIDYLIKNGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVIDLSKRMEAVGASALS
                     IITPYFVTPTQQELILHYETIANSVNLPIIMYNMPDKTGINIEPESVCKLSKIKNIVG
                     IKDSSGKLDNMKAYIEVTKNEDFSVFSGSDSLILDSLKAGSQGAVAATANFLTKIDIS
                     IYENFMRGDLEEAQKAQSSIEEFRRILKLGTIPSVLKKTIVLNGIDVGTARLPVIEPT
                     GDALEEIKNVVENYREMF"
     gene            5511..6143
                     /locus_tag="ACOIAP_002868"
     CDS             5511..6143
                     /locus_tag="ACOIAP_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HGZ2639747.1"
                     /translation="MKKMNITKRMAECGALAIVREEKLNRACEIVEGCIKGGITVVEM
                     SYTLNNAGEIIQGLNKKYGEALCVGAGTVLDSETARHAILHGAQFVISPNYNEDVAKI
                     CNRYQIPYAPGCTSLTESVEALSLGAAFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINLENLHVWLENGVDVCGFGGLLTKGTVEDIAKNAKKIREIIKNIREV"
     gene            complement(6329..7606)
                     /locus_tag="ACOIAP_002869"
     CDS             complement(6329..7606)
                     /locus_tag="ACOIAP_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2639748.1"
                     /translation="MENTVKNSKIFYGWWILLACIIVMALGYAPIVSLASLFIKPITE
                     DLGFTRSAYTLSTAIISLMCMFMASITGKLMSTKHMHLIHVICVAGLSIFYGLYSLAT
                     SIFHFYVVSFFIGLFTYGATKMPVSILISNWFYEKRGLALSLSMAGTSISGTLLSPLV
                     VKLITNYGWRQTYVYLAIVMFLIMVPATIFIVRQFPSCKGLQPYGYDRHQDNTNKNTI
                     KNEWNISLKEAKKLPVFWTFTFGVTLILLTGCILGHIPAYLEDSGYNPSLTASIVSTY
                     LFIAIWGKVVLGHVFDKLGSKAGVLLGNICFIISIVCLLFIEFKPMLYLMTFFFGIGT
                     CIGTVTTPVLTSRIFGTKHYPEIYGFVASCTCIGSIIGTPAIASIFDLTGSYKMAWII
                     LIILSIIMTLALVYSINEGHKYRLKDVSQQTIK"
     gene            complement(7608..8798)
                     /locus_tag="ACOIAP_002870"
     CDS             complement(7608..8798)
                     /locus_tag="ACOIAP_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2639749.1"
                     /translation="MSDMFMNLAKQFESEIISWRKHFHENPEIGMELPNTVNFIQKKL
                     EEFNIEYKVGCNGYSITGLIGNKNSGKCILIRSDMDALPVIEQTELEFKSNNNYMHAC
                     GHDAHMAILLGAAKILKLKENELEGSVKLMFQPGEEVFEGAKAMISEGVLENPKVDSA
                     FGMHVVPTMPNKSVVYGKEFMSSCYGFKITIKGKGGHGSQPENCIDPINTGVHIYLAL
                     QELISRECPPQELATLTLGQFKSGEACNVIPNEAVLQGTLRTFSPTTRDLLINRINEV
                     VQSVSITYRCSADIEVLSNVPALICNDELNKKFMSYIYELDKNIKMSEFNHTMGSEDF
                     AYISEKVPTCFMYLGAGIEDTSKWYVAHNPKVMFNDKCLALGSAIYAQCAYQWLKNMS
                     KESL"
     gene            8983..9861
                     /locus_tag="ACOIAP_002871"
     CDS             8983..9861
                     /locus_tag="ACOIAP_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGZ2639750.1"
                     /translation="MNLNYFQYLVEVANIGSISKAAEKNFVSQPYLSGIIKKMEDEVG
                     FLIFKRTNLGIELTEKGEIFINEAKKILIGIENIKNINTKNEEGLSIGMVYSLFFTKC
                     FLKFKKFKPTDLQDKVYEMSPMEIFKALIDNKIRLGLFSYATKKKDKYWNIAKKHHLK
                     CWSIYEDLHPYVIMSRSHPLALNDSITISDLNSNPYVVYDKSEFLIYLDMIGIRKHPD
                     LLLVSDRGSFSDAILDNNYLGITTYFSEINEQDNKFIYIKLEDCDETIGIGYAILDNY
                     KLSQREKDFIKFIKNK"
     gene            10640..13147
                     /locus_tag="ACOIAP_002872"
     CDS             10640..13147
                     /locus_tag="ACOIAP_002872"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HGZ2639751.1"
                     /translation="MKEDIGLHRMCKEEQVTKNEVISEDILKSMSMGVSKHFLDDSFT
                     ILWGNTSFYQLFGYTEEEFLFKFSSLKDYYEQNLYNFESMKNHFLEAYHRGEKSTEYQ
                     ICISANNVDPVWVIMNGILIESEENEKSMVYILYSRINELEIKQEEASKMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKQSCNILQASVNELIGRKCYEVIQDRTSPCPFC
                     TNPYLKKNDVYEWEFYNKKLKRTFMIKNRMLNWKGRRARIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRVDARDYLTILWYNDIFLNMIEYTKEQFAEELDNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEARIYTRSREERIWTVTLCYVSGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQYISEKDALTGIYNRAETERQIKKYFEENLNSMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMCDSDVVGRIGGDEFTIFMKDISSVKDAEKKAEEL
                     LYMFRHLFQKEKSSLKVTCSIGIAIYPKDGTTFKEIYTRADKALYQAKNIGKNNYVIY
                     NQDSFKELEAFNCSSLGTVIDSEKQYAECPDNLTRYIFRMLYQTDNIDETINMILEVV
                     GKQFNVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNNNYQDYEDYEKLFGDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDKVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNKKFNQQMQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKLQIGQPCYLDAVDIHKISIAWNQKEAYLCISMI"
     gene            13490..15658
                     /locus_tag="ACOIAP_002873"
     CDS             13490..15658
                     /locus_tag="ACOIAP_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGZ2639752.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKFNKNYSNWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGEFPN
                     TNTNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFDKISEVGESGILYISTQNKDT
                     INKILKELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSR
                     EASILRLNGYSKLDIITRVIRSILRIMILSSITSLLIYIIYILKLNLGVRACLYFVIF
                     SIICILINIFISILIVGFNIRSSKYVLTLNGKKPYGFVNIIHFTLKIVFVSFLILSIN
                     NCILNYNILQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKSLVE
                     EKDAFLIDTTNFEKLENGSYMYEINSKGKKPEVSQYGKNIKINKNYLKVNPIYSNGKE
                     IFNLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNEELNRDLNKTK
                     KSDLNVNIIYVDNNQSYFTYNSLVMDDNRNLINDPIAIVDIDNIDDSFYLSYISRCVY
                     FNSKKLDALADISKIIEAQGVEANIQSLRAVYNEYGLEINKLEKYLNSEIFTIIIIAI
                     SNLMITYNIVVSYYERNKYKLYIKKIFGYSATARSILLIISLILTNVIPIGIISTRVD
                     LSNNIVLFGLLILVVEVIISIILDKIISNSSFNKIIKGEH"
     gene            15663..16280
                     /locus_tag="ACOIAP_002874"
     CDS             15663..16280
                     /locus_tag="ACOIAP_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative bacteriocin export ABC transporter"
                     /protein_id="HGZ2639753.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVESNLKIAL
                     KYQKNINRDEKINYVLESVGLGKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNNNGKTIVLVTHDLELSEQVDKIIKL"
     gene            16469..16813
                     /locus_tag="ACOIAP_002875"
     CDS             16469..16813
                     /locus_tag="ACOIAP_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGZ2639754.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLELEGDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSAIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVIKKA"
     gene            17385..18251
                     /locus_tag="ACOIAP_002876"
     CDS             17385..18251
                     /locus_tag="ACOIAP_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGZ2639755.1"
                     /translation="MISIHKNIYDDKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCMNLQPDFKCSVHDNLMKRGFKGCTAYDCFGAGQKVAQVTYKGIDWMQSPELA
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKINLRIEETEKITNMSSEQIVDLD
                     IISHREKVNSLLLQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKTNLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PVSLIRPKYWGK"
     gene            18364..18768
                     /locus_tag="ACOIAP_002877"
     CDS             18364..18768
                     /locus_tag="ACOIAP_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HGZ2639756.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNEYYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            18944..19393
                     /locus_tag="ACOIAP_002878"
     CDS             18944..19393
                     /locus_tag="ACOIAP_002878"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639757.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIKFLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKAFDRSEIDGQGNPFPILHMKLI"
     gene            complement(19550..19927)
                     /locus_tag="ACOIAP_002879"
     CDS             complement(19550..19927)
                     /locus_tag="ACOIAP_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGZ2639758.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLESNPNNPVMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSRETIEEISIKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            20198..21106
                     /locus_tag="ACOIAP_002880"
     CDS             20198..21106
                     /locus_tag="ACOIAP_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HGZ2639759.1"
                     /translation="MNIIEIRSDKIYKKIMDAPINKKEDIYIYELMKPFEFKWKCMNV
                     PIVAKQKGGYDVIIASEMLGVLSPKDIDEKQKKNINMLSTDKIWNTCKETIENSINAF
                     IKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINRLPV
                     LIAHECNHNIRFQFIEWNNNITLEEMMINEGIAENFAKWMFGEEMVGPWVSRTDIETL
                     NTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKYYLE
                     KTNKSIIEATLLPYSEIIEAVEEFWE"
BASE COUNT         8251 a         2417 c         3493 g         7088 t
ORIGIN      
        1 aagtttaatt tttgtctcaa tctaaaacaa aagttatact taaatgaaat tgaaaacgat
       61 aaaattctca aataaaataa gtattgtgga ggtgataaaa aaatccaatg ataatatgaa
      121 gactaatctt aataagaaag tagggattaa ttatagtgga caaagaaatt gtatcaattc
      181 tccaaatttt attaaatagc acattgatta cgactaatgg attacaagag gaatctaatt
      241 catcaaagag acaaattact tatagaataa ataaaatcaa tgacatgctt aaagtaaaaa
      301 atgtaccact tatatgttta agagctgata aagatattat cgttagaaaa gaaacaaaaa
      361 aagcaatcaa agaaatttta gaaaaaaact attctaagaa tacttattac tttagtaaag
      421 ctgaaagact tttatatatg tatttaatgc tttttattaa tatggaggat atatcaatta
      481 atcattttat aaattctata aaagtaagca ggtctactgt aaatctagat ttcaaagatt
      541 taataccaaa tcttgaaaaa aagggcattg aggtcaagaa caatcgtata aatggttatt
      601 acttagttgg aaatgaaatg gaaataagga gagtgcttat taagagtatt atagaaacct
      661 tgtctaatga gaaaagttca agagtatttg atatttttat taaagaatat aatttagaca
      721 gttttgaaga ggataaagaa attatattga agttaataaa aaaatatgaa attacttttg
      781 ttgaagatag attaatagaa tttatatata tatttatctt tctaaaagca aggatgtatt
      841 caactagaat agttactcat gaaaatgtag atattcctaa tattgcagtt atgagttcaa
      901 tgaaagagta taaatttgct aaggaattat tagaaacata tgagagtgaa gataagataa
      961 agtctcataa tataatgtat attagtgctt ggattttagg tatatcagta ggaaattatg
     1021 aagaagatac agaagataag gatgtaattt caaaaattgt aaataaaatg atgacaaagt
     1081 ttggatattt aagtggagtt tactatataa gtcaagaaaa aatatttaaa caattatatt
     1141 ctcattttag accagcatac tatagacttt tatttaaatt acctatctat aatccgattt
     1201 gtgaaaaagt aaaagaagaa tataaattag tttatagaat tgtaagtaat gcaatgaaag
     1261 agttttgcgg attatttgga gaagaaattc aggaagaaga gttagcatat cttacaatgc
     1321 actttgcaac ccttttttca aataaaaaag aatttgatgg ttttagaaaa agaatagcat
     1381 taatagtttg ttcaaatggc gttggtagtt cagccatttt acatgcagaa cttacaaact
     1441 tatttcctga tttacatttt ataccaatgt cggaatcagt tggattggaa aatatgagtg
     1501 agcctgtaga tattgtattt actactaatt ataacacaga gggtttaaaa acagatgtgc
     1561 cagtaattaa agtaagccct gttatgacta caaaagaaaa atataagatt acacgtgaag
     1621 tgtatattca attaggtgat atttttttaa gacaacctaa aatagatgag gttatgaata
     1681 taataaaaaa atatgcaaat gtaacttctg aaagtattct ttcaagtgag ttattaactt
     1741 attttacaca gatagagaat tttacatcta aagaaggaga ggggcctatg ctaagtgaga
     1801 ttactaatga aacactagta aaaataaagg taaaagctaa gaattgggag gatgctatta
     1861 gacagtcagc ttctgtatta gttgaaaata acaaaacaac tgaagggtat gtagaggcta
     1921 tgattaattc agcaaaagca tctggaccat acatagtaat tacaaaacat gttgcacttc
     1981 cacatgctag accagaagct gggtcaaaag agattgcaat aggtattgct actttagata
     2041 gtcctattga gtttgggaat gatgaaaatg accctgtaaa atatgtattt tgtctaagtg
     2101 caatagataa caatagccat ctacgtgcta tgtctgaact ggttgagcta ttggaagaag
     2161 aagagttttt taaggtttta gatagtgcta aagaacccaa agaaattatt gattatataa
     2221 aaacacacga attataaagg agaatttaat tatgtataaa attttaattg catgtagagc
     2281 aggagttggc tcaagtttaa tgttaaaaat aaagactcaa caaattgtta aggaaaataa
     2341 ctttccaatt gaagtagaac atggttcatt agattcatta aatggattca atggagatgc
     2401 tgtagaaaca ttaattgatg ttgctgaaga attaaaaaat aaacatttga agtttgatat
     2461 aattgggatt cacaatattg ttgaccgtaa cgaaataaag acagcactag aaaaattcct
     2521 tgcttcaaaa gagggataaa tttaggataa taaggaggaa tatttatgga atttattatt
     2581 agtttgctga gtacacctgc tgttttgctt ggtgtagttg catgtatagg attgattctt
     2641 caaaaaaaat cagctgttga agtatttaca gggtcttcaa aaacacttat aggattttta
     2701 atatttggta ttggtgcctc tgctatgaca ggagcacttc aaaatttcaa taaattgttc
     2761 caacatggct ttggaattac tggtgttata gcttcaccag aagcagctac agcacttgca
     2821 caaggtacat atggttttgc agtttcgtgt acattaattc ttggattcat attaaattta
     2881 gtatttgcgc gtattacaaa gtttaagaat attttcttta cgacaggtca cagtttgttc
     2941 ttttcttgtg tattagtttt aatcatgaaa gcacatggat tcgataatac aatcactatt
     3001 ttaataggtg gaactatctt aggatttatg tctgctgcac tacctcaatt ctgtcaaccc
     3061 tttatgcgtg aattaacagg tggtgacgaa caagctattg gtcactttaa catgattggt
     3121 tatggtctat caggttatat tgggcgttta ttttcgaaac ataaagatga tacaacagaa
     3181 actatagaat ttcctaaatg gttatcaata ttcagagatt tcttaatggg tctatccata
     3241 gttatgttaa tcttatttta tattgcaaca ttaaaagctg gtcaagcatt tactcaagaa
     3301 attgctggct caacgcattg gttagttttc ccacttatag aggcatttac atttgtagca
     3361 ggtatgtcaa tattgatgtc aggtgttcgt atgttcttag ctgaaataac tgcagcattt
     3421 gtaatcattt cagaaaagta tattccaggt tcacgtcctg cactagatgt tccaacagta
     3481 tttccatatg caccaaatgc agttattatt ggatttatca cagcatatgc tgcaggtcta
     3541 ttagcaattg ctattatggc atcatttcct agtatatttc ctgtagtaat tattccagct
     3601 gctcatatat gttttttctc aggaggtaca gctgcaatat ttggtaatag ttcaggagga
     3661 tggagagggg ctattgctgg gtcatttgtt gtggggttat tacttgcatt tttaccagtt
     3721 atactatatc cagtttacgg gactcttggt atagagggtg caactttccc taatattgat
     3781 tataacgtag ttggttcgat attacataat attttacaat ttataaaacc tatttaaact
     3841 aaattatata aagatatagt catagtcact atattttaag gaggatacat tttatggaaa
     3901 atacattatc tgaattttta gataatatat ctaatgaatt gtcagaattt attgcctcaa
     3961 tagatgagac atccataaat aaagcatgca atttaatttt tgaagctgaa aaaaatcatg
     4021 gacgtgtaca tgtgactggt atcggcaaac caggacatgt atcaggatat atttcatcat
     4081 tgctttcatc tactggaaca ccagcatata tattacatgg tacagaagca gtacatggat
     4141 caagtggaca agtagttgaa ggagatgttg ttattgcaat atcaaatagt ggtgaaactc
     4201 aagagttaaa aggaactctt gaaacactaa aaataaatgg agcaaagata attggtgtaa
     4261 gtggcaatga gagttcattt ttaaaaaata tttctgatat cttcttgttt gcaggtgtta
     4321 aacaggaagg tgattgcctc aataaagctc ctcgtgcttc aattctagct gaaacaatag
     4381 tattacaatc attgagtgtt gcactacagt atgctaaagg tcttaataca cagcagtatt
     4441 tgaagtggca tccagcagga agtcttggaa aatctattag agagggaata taattttatg
     4501 aaatataaag gaattatatg tgcaatgata acaccatttg atgaaaatca aaatatcaat
     4561 tcacgagcaa cgtgtcaact aattgattat ttgattaaaa atggaattta tgggttattc
     4621 attttaggca ctaatggtga atgtcatgtg ttgacagatg atgaaaaagt tgaatttgca
     4681 aaaattgtta ttaatcatac aaataatcgt gtgcctgttt ttgttggaac aggtggcaat
     4741 tcaactcgtg aagttataga tttgtctaag agaatggaag cggttggagc aagtgcatta
     4801 tctattatta caccatactt tgttacacca acacaacagg aattaatctt gcattacgaa
     4861 actattgcta attcagttaa tttacctatt ataatgtaca acatgccaga caagactgga
     4921 attaacattg aaccagagtc cgtgtgtaaa ttgtcgaaga taaagaatat tgttggaatt
     4981 aaggatagta gtggtaaact tgacaacatg aaagcttata ttgaagtaac taagaatgag
     5041 gatttcagtg tattttcagg gtcagattca cttattttgg atagtctaaa agctggtagt
     5101 caaggtgctg ttgcagcaac agcaaacttc cttacaaaga ttgatatctc tatctatgaa
     5161 aactttatga gaggggattt ggaagaagct caaaaagctc aaagtagtat agaagaattt
     5221 cgacgtatct taaagcttgg gacaattcca tctgttctga agaaaactat tgtattgaat
     5281 ggaattgatg ttggaactgc acgacttcct gtaattgaac caactggaga cgcacttgaa
     5341 gaaattaaaa acgtagttga aaattataga gaaatgtttt aataaaagta gtgagaacag
     5401 ataacataac tggcggaagt tacattagta tataattaat atatgtatta taaaatatgg
     5461 ctaaaattat tggataggta aagtggtttg atgagtatag aggtgataat atgaaaaaga
     5521 tgaatataac caaaagaatg gcagaatgtg gtgctcttgc aattgtaaga gaagaaaagc
     5581 ttaaccgtgc atgtgaaatt gtggaaggtt gtataaaagg tggtataaca gttgtagaaa
     5641 tgagttatac cctgaataat gctggagaaa taattcaagg acttaataaa aagtatggtg
     5701 aagctctttg tgtgggagca ggaacagttt tagatagtga aacagctcgt catgctatat
     5761 tacatggagc tcaatttgtt atttcaccaa attacaatga agatgtagcg aagatttgca
     5821 atagatatca gattccttat gctccaggat gtacatcatt gactgagtct gtagaggcac
     5881 tgagtttagg agcagctttt ataaaagctt tcccaatatc agatttctat ggacctaaac
     5941 tagtaaaagt atttaagaca ccaatacctg atatgccagt tttagcaagt ggaggaatta
     6001 accttgaaaa cctacatgta tggttagaaa atggggttga cgtttgtgga tttggtggtt
     6061 tattaactaa aggtacggtt gaggatattg ctaaaaatgc taagaagatt cgtgaaatca
     6121 ttaaaaatat aagagaagtt taatattggg tttgtatcat agcagtttat aattgctatg
     6181 atacaaaccc tttagtattt gttatcttaa tttaaaatat agatgaaatt agtaatgcaa
     6241 ctatataagg attgctaatc aatatatatt ttttatgtat ttatgaattt gtaggtaagt
     6301 acaaaagata aatattttat ttataaattt actttattgt ttgttgtgaa acatctttta
     6361 gcctatattt atgaccttca ttgatactat aaactaatgc taaagtcata attatagaca
     6421 gaattattaa aataatccaa gccatcttgt aagaaccagt taagtcaaag atgcttgcaa
     6481 tagctggtgt acctataatt gagcctatac aagtgcaaga ggccacaaac ccatatattt
     6541 ctggataatg ttttgtacca aatattctac ttgttaaaac aggggtagtt actgtaccta
     6601 tacaagttcc aattccaaag aagaatgtca tcaagtaaag cattggttta aattctataa
     6661 aaagcaaaca aactatagat attataaaac aaatattgcc taataatact cctgccttag
     6721 agcctaattt atcaaataca tgccccaata caaccttacc ccatattgct ataaataagt
     6781 acgtagatac tattgaggct gttaaagaag ggttatatcc actgtcttct aaatatgctg
     6841 ggatatgacc aagaatacat ccagtaagca atattaaagt aacaccaaat gtgaaagtcc
     6901 aaaatactgg taactttttt gcttctttaa gagagatatt ccattcattt tttatagtat
     6961 ttttgttagt attatcttga tgtctatcat atccataagg ttgcaaacct ttgcaagaag
     7021 gaaactgacg aacaataaag attgtagctg gaaccataat taaaaacata acaatagcaa
     7081 gataaacata agtttgtctc catccataat tagtaatcaa cttaactact agagggctaa
     7141 gtaatgttcc actaatagaa gtaccagcca ttgaaagact tagagcaaga cctctttttt
     7201 cataaaacca gttagagatt aatatggata caggcatttt agttgcacca taagtaaaaa
     7261 gaccaataaa gaatgatact acataaaagt ggaaaattga tgttgctaat gaatataaac
     7321 cgtaaaatat agaaagccct gcaacacaga taacatgaat taaatgcata tgtttagtag
     7381 acataagttt tcctgtgata gatgccataa acatacacat tagtgaaatt atagcagtag
     7441 atagagtgta agcacttcta gtaaaaccaa ggtcttcagt tatgggtttt ataaataaac
     7501 ttgctaagct aactatagga gcatatccta aagccattac tataatacat gctaagagaa
     7561 tccaccatcc ataaaatatt ttactatttt taactgtgtt ttccatatta taaactctcc
     7621 ttactcatat tttttagcca ttgatatgca cattgagcat atatagctga accgagagca
     7681 agacatttgt cgttgaacat tacttttgga ttatgggcaa cataccattt agaagtatct
     7741 tctataccag cacctaagta cataaaacat gtaggaacct tttcagaaat ataagcaaaa
     7801 tcttcagaac ccatagtgtg attaaattct gacattttaa tgtttttgtc taattcatag
     7861 atataagaca tgaatttttt atttaattca tcattacata ttaaagcagg tacatttgat
     7921 aaaacttcaa tatcagcact acagcgataa gttatagaga cactttgtac aacttcatta
     7981 attcgattta ttaataaatc ccttgtcgtt ggagaaaatg tacgaagtgt accctgtaaa
     8041 actgcctcat tggggatgac attacaagcc tcgcctgatt taaactgacc caaagttaga
     8101 gttgctagtt cttgaggtgg acattctcta ctaatgagct cttgaagagc taaatatatg
     8161 tgaacgcctg tattgatagg gtctatacaa ttttctggtt gagacccatg accacctttt
     8221 cctttaatgg taatcttaaa tccataacaa gaagacataa attctttgcc ataaaccaca
     8281 gacttatttg gcatagtagg cactacatgc attccaaatg ctgaatctac ttttggattc
     8341 tcaagaactc cttctgaaat catagccttt gctccttcaa aaacttcttc tcctggttga
     8401 aacattaatt ttactgaccc ctcaagttca ttttctttaa gctttagaat cttagcagct
     8461 cctagaagta ttgccatatg agcatcatgt ccgcatgcat gcatataatt attatttgat
     8521 ttaaactcca gctctgtttg ctctattact ggaagcgcat ccatatcact acgaattaat
     8581 atacattttc cgctattctt attacctatt aaacctgtta ttgaatagcc attacaacca
     8641 actttatatt caatgttaaa ttcttctaat tttttttgaa taaagttgac tgtattggga
     8701 agttccatac ctatttctgg attttcgtga aaatgttttc tccagctaat aatctcactt
     8761 tcaaactgtt ttgctaaatt cataaacata tctgacatat ttatctctcc ttttaaagat
     8821 tttaagtttt aattatactt atccaaaaac ttgtaattaa tactaagttg tgttagtttt
     8881 atgatagcat attaaatttg tcaatcggta ttagcaaaaa aacatgaggt ataaggaaaa
     8941 ggttatatca atttataata tatactagtt tagggggata tgatgaattt aaattatttt
     9001 caatatttag ttgaagttgc aaatataggc tctattagta aagccgcaga aaaaaatttt
     9061 gtatcacaac catatttaag tggtattatc aaaaaaatgg aagatgaagt agggtttttg
     9121 atttttaaaa ggacaaatct tggtatagaa ttaactgaaa aaggcgagat ttttataaat
     9181 gaagcaaaaa aaattttaat aggaattgaa aatataaaaa atataaatac aaagaatgaa
     9241 gaagggttgt caatcggtat ggtctactct ttatttttta cgaaatgttt tctaaaattt
     9301 aaaaagttta aacctacaga cttacaagat aaagtctatg aaatgagtcc aatggaaata
     9361 ttcaaagcat taatagataa taaaattagg ctagggctat tttcctatgc gactaaaaaa
     9421 aaggacaaat attggaatat tgctaagaag catcatctaa agtgttggag tatatatgaa
     9481 gatttacatc cttatgtaat tatgtcaaga agccatcctt tagcattaaa tgattcaatt
     9541 acaatatcag atttaaacag taatccttat gtagtttatg ataaaagcga atttttaata
     9601 tatctagata tgataggtat aagaaagcat ccagatttgc ttttagtttc agatagaggt
     9661 agtttttctg atgcaatatt agataataat tatctaggta taaccactta tttttcagag
     9721 attaatgagc aagataacaa atttatatat ataaagttag aagattgtga tgaaactata
     9781 ggaataggtt atgctatatt agataattat aaattgagtc aaagagaaaa agattttatt
     9841 aaatttatca aaaataagta aaatattcca tatttaatgt gggtagattg tcatatttca
     9901 aatcaataaa taattagtat ataccatata agtaattgct tatatggtta tttttagtga
     9961 agcaattact ttagaaaatg aaacagataa ttatgtaata aataagagat agaattttta
    10021 tttatctaac attaagtata aaagaaaatt actatgactt aataaaataa gatattaaca
    10081 atgaaattct tgataaatac cttttaattt aggcattata aagtttaatt gtacatgtgt
    10141 tacatatttt cttgaaattt ataattaata ttaaacttcc tcagttcaat aataatatac
    10201 taaatttata agttagtatt attcatatgt aaagctgagt gctttactaa tttatatcgc
    10261 ataaaatttc agcaatttta tcttaacttt tctatataaa aagaactgct ttaaaacttg
    10321 gggtatgata taatttcatt aaaagaagac ggtttttagt aaatactaga aaataatatg
    10381 tttttataga aaaagttaaa tatggattta agtgaataag aatcaataag taaggtatta
    10441 aattatgaat agggtacaaa acattactga attaaaagtt ttagagggag aagtttagca
    10501 aggatgtgtg aaaattaatt ctcaaacagg aattattgta tatgagataa atttacacac
    10561 attgaagatt cacttttatt tatactaaaa agtagattgt cttaaaggtg ggtctaaaga
    10621 taggaggata atcaaaataa tgaaagaaga cattggatta catcgaatgt gtaaagaaga
    10681 acaagtaaca aagaatgaag ttatttcgga ggatatttta aaatccatga gtatgggagt
    10741 cagtaaacat tttttagatg attcatttac aatactatgg ggaaatacat cattctatca
    10801 attatttgga tatacagaag aagaattttt atttaagttt tctagtttaa aagactatta
    10861 tgaacagaat ctttataatt ttgaatctat gaaaaatcat tttttagagg cttatcatcg
    10921 tggagaaaag agtacagaat atcaaatttg tatttcagca aataatgtag accctgtttg
    10981 ggtaataatg aatggtatat taattgaatc agaagaaaat gaaaaatcaa tggtctatat
    11041 attgtattca agaattaatg aattagaaat aaagcaagaa gaagcatcta agatggaaaa
    11101 agagagtaca gagaatttta aatggatgat gtcagagtat gctggaaatg tttatattag
    11161 tgatatggat acatatgaat tactatactt aaataagcaa tcatgtaata tcttacaggc
    11221 atcagtaaat gaactcattg gaagaaagtg ttatgaagta attcaagata gaacttcacc
    11281 atgtccattc tgtacaaatc catatttgaa aaaaaatgac gtatatgaat gggaatttta
    11341 taataaaaaa ctgaaacgaa cgtttatgat taaaaatcgt atgttgaatt ggaaagggcg
    11401 tagagctcgt atagaattat cttatgatat gtatagtgct gaatataaat tagcaaaaaa
    11461 agatcaagaa agagaatcaa ttttgaaaac cattccagca ggaatggttc gagtagatgc
    11521 aagagattat cttactatac tttggtataa tgatatattt ttgaatatga ttgaatatac
    11581 aaaggaacag tttgcagagg aacttgataa tcaatgtgga tatttatttt ctgaagatta
    11641 taaacgtagt aagaagctag cacaagattt aaaggagtct ggggataatg ttgtatttga
    11701 agcaagaata tacacacgtt caagggaaga acgtatatgg accgttacat tgtgttatgt
    11761 cagtggagaa gacagctggg atggaatacc atctttttat agtataggta ttgatataac
    11821 aaaggaaaga aaacagattg agaaattaca gtatatatca gagaaagatg cattaacagg
    11881 aatttataat cgtgctgaga ctgaaaggca gattaagaag tattttgaag aaaatttaaa
    11941 ttctatgggt gcactgttta tgattgatac agataatttt aaacagatta atgatacaga
    12001 agggcatatg attggggata tagtgcttac tgagatggca tcaggtatga aaaaaataat
    12061 gtgtgacagt gatgttgttg gaagaatagg tggagatgag tttacaattt ttatgaagga
    12121 tatttcctca gttaaagatg cagaaaagaa agcagaagaa ttattgtata tgttccgtca
    12181 cctatttcag aaagaaaaaa gttctctaaa agtaacttgc agtataggaa tagctatata
    12241 tccaaaagat ggtactacat ttaaggaaat atatacaaga gctgataaag ctctgtatca
    12301 agcaaaaaac ataggaaaaa ataattatgt aatctacaat caagattctt ttaaagaatt
    12361 agaggcattt aattgttctt ctcttggtac agttattgat tcagaaaagc aatatgctga
    12421 atgtcctgat aatcttacac gttatatatt ccgtatgctt tatcagacag ataatataga
    12481 tgagacgatt aatatgatac ttgaggttgt tggtaagcag tttaatgtaa gtcgtgttta
    12541 tatttttgaa aatacagagg atggtcgata tacttctaat acctatgaat ggtgtaatga
    12601 aggaatctct tctcaaatgg cttatttgca aaacaacaat tatcaagact atgaggatta
    12661 tgaaaagctt tttggagatg aattagtttt ttattgtcga gatatccaca cattaagtcc
    12721 taaactagaa gaattgtttt ctagtcaagg tatccactct acacttcaat gtgcatataa
    12781 agaagataaa gttttcagtg gatttgttgg atttgatgaa tgcacaggat tacgtctatg
    12841 gtcacaagag gaaataagta cattatcatt gatttctcaa attatatcaa tgtttttgca
    12901 acgtaaaaaa aataaaaaat ttaatcaaca aatgcaacaa tatcagaata ttttagataa
    12961 tattgaccag tgcatttgtg tgattaacaa agaaaataat tttttattgt atgtaaataa
    13021 aaaatttaaa aatacatatt ctaaattaca aattggacaa ccttgttatc ttgatgctgt
    13081 agatattcat aagatatcca ttgcatggaa tcaaaaagaa gcatacttat gtattagcat
    13141 gatttagtgg taaggtaaag tttgtattga acttaaacta aatttagttt taaataaaat
    13201 attattttgg ttgattactg aaaatactag aatctatgtt aatgaattat actaattttg
    13261 taccactatt aaaatattgt ttgataaaaa taaataaaaa tcttaaaaca gttggttata
    13321 aaaaattaac tgttttttat tgtttttata tttgtgacaa aatagacaca tgccatttag
    13381 aatgtgacaa tatagtagtt gtttaaaaga gatgcaaagc attatacttt aattaaagta
    13441 tagtgtattt ttgcttttaa aataaaaaca attaggggga gagttataat tgaaaaaaat
    13501 aatatatgta ttatttacaa ttgaactatt aatagtatct ttattaggtc taaatatagt
    13561 taaagataat gaaattaata atattttata taatgataca acaagtatat ctgtaatgtt
    13621 taaagattat aaaaagttca acaaaaatta tagtaattgg attaaagata ttgcagacga
    13681 aaataatgtg actatatcaa agtatgtttt taataataat gaaaaattat ctatatatac
    13741 aactgataca agtttaaata ataatataaa gttaaaatca ggagaatttc ctaatactaa
    13801 cactaattca aatgaattta ttagtaatat aaacactaat aatagtaatc aagtaggtaa
    13861 attctcaact atgagtaaag acatatcaat tttgattagg gattttgata aaataagtga
    13921 agttggagaa tcaggaattt tatatatttc aactcaaaat aaagatacaa taaataaaat
    13981 attaaaagag ttaaatgtag acagaagtat ttttgtagca agactacatg atagatatgt
    14041 taattcaaat ttatacttaa atccttcaat aattagagat ttaatactaa ttatcctttg
    14101 cttcttggcc acaataatac attattcaat tagtgtgagt agagaggctt ctattttaag
    14161 attaaatgga tattctaagt tagatataat tactagagtt ataagaagta tacttagaat
    14221 tatgatttta tcatctatca catcattatt aatatatata atctatattt taaaattaaa
    14281 tttgggtgtt agagcatgtt tatactttgt tatattttcg attatatgta ttttgataaa
    14341 tatttttata tctatattaa tagtgggttt taatattaga agttctaaat atgtgctaac
    14401 tctaaatgga aaaaaacctt atggttttgt aaacataatt catttcacat tgaaaattgt
    14461 atttgtatca tttcttatat tatccataaa taactgcatt ttaaattata atattctaca
    14521 aactcagtta ggaaatctat ctgagtggga taaagcaaaa aatgtttata accttactct
    14581 taaagataca ggtgaacaat ctttaggaaa ggaagaagta ataaaaaatg ccaagattaa
    14641 aggattttat aaaagtttag tagaagaaaa agatgctttc ttaattgata caactaattt
    14701 tgaaaaactt gaaaatggaa gttacatgta tgaaataaat tcaaagggta aaaaaccaga
    14761 agtaagtcaa tatggtaaaa atataaagat aaataaaaac tatcttaaag ttaatcctat
    14821 ttactcaaat ggcaaagaaa tatttaatct aattgactat gacgataaga ctataaattt
    14881 attagttcct aaaaagttac aggtacatga aaatgagatt aaaaaagagt ttagagaatt
    14941 attttatttt gaaaaaatag aagtagaaaa tatgtataat gaagaattaa atagagattt
    15001 aaataaaaca aagaaatcag atttaaatgt taatataata tatgtagata ataatcaaag
    15061 ctactttact tataactcac ttgttatgga tgacaatagg aatctcatta atgacccaat
    15121 agcaatagtt gacatagata atattgatga ttctttttat ctttcctata tatctagatg
    15181 tgtatatttt aattctaaga aattagatgc tcttgcagat ataagtaaaa ttattgaagc
    15241 tcaaggtgta gaagcgaata tccaaagttt acgtgctgtt tacaatgagt atggtttaga
    15301 aataaataaa ttagaaaaat atttgaatag tgagattttt actataataa taatagcaat
    15361 atcaaattta atgattacct acaatatagt agttagttac tatgaaagaa acaaatataa
    15421 gttatatatt aaaaaaatat ttggttattc agctacagct agaagtatat tgttaataat
    15481 ttcattaata ttaacaaatg ttattccaat aggcattata tcaacaagag tagatttaag
    15541 caacaatatt gtcttatttg gacttcttat attagttgta gaagtaatta tatctattat
    15601 attagacaag attatctcaa atagttcatt taataaaatt ataaaaggag aacattaaaa
    15661 agatgatttc attaataaat atatcaaaaa aatttaaaga taaatctata atagacaaat
    15721 ttaacctaga aatttctaag ggcgaatttg tagcgataac aggaaatagt ggctcaggta
    15781 agacaacttt acttaatata atgggattat tagaaaaacc taattctggt gatattataa
    15841 taaataatat aaaaaatcca aatagtaaac aaataagaat tttacaaagg gatttttatg
    15901 gttacctatt tcaaaattat gctttaattg agaatgaaaa tgttgaaagt aacttgaaaa
    15961 ttgctttaaa gtatcaaaaa aatattaatc gtgatgaaaa aataaattac gtacttgagt
    16021 ctgtaggtct tggaaaatac aataaaaaaa agatatacga attgagtgga ggagaacaac
    16081 aaagggtggc gttagcaaga gtaatattaa aagagtgtga agtaatattt gcagatgagc
    16141 ctacaggtaa tttagataaa aaaaatagag atatagtatt tgatatactt aaaagtctaa
    16201 ataataatgg taaaactatc gtattagtaa ctcatgattt agagctatcg gagcaggtag
    16261 ataaaattat aaagttgtaa taatatcaat tacaataaat atgggaaaga gattacagct
    16321 aaatcaaatt caacaatact aggaatataa tttaaatatt aaataaatta gtagtttgta
    16381 aatataagta taatatgata ttataaaggc tcaaaagaaa ttttatataa taagaaatct
    16441 aaaaataata aatggaggac atataaatat ggaaaattta ccaaattgcc cgaaatgtaa
    16501 ttcagaatat acttatgaag atggaactct tttagtttgt ccagaatgct ctcacgaatg
    16561 ggcattagga ttggaactag aaggagattc aaatattatc aaagatgtaa atggaaatgt
    16621 attaaatgat ggagattctg ttacagtaat tagagacctt aaagtaaaag gaagttcatc
    16681 agctataaag attggaacaa aagtaaaaaa tatccgttta atccatgact catcagatgg
    16741 acatgatata gaatgtaaga tagatggttt tggagctatg aagctaaagt cttctgttat
    16801 taaaaaagcg taatattata actaaactat attgtttatt attttcaagt atagtataaa
    16861 accataagaa tctattaagt aataaaaatt tacttattta tctttatatt ttcttatggt
    16921 tttattaaat atagatttta ttgaatacca aaatattctc tcctctgcaa ataagccaat
    16981 cttatttatt taaactaata tattttgtac tatttatatt aaaattgtaa atttaaatgc
    17041 tatgttattt agctttatat agttaattta caaatttctg attttataaa ttgtatttat
    17101 tatatcttta atgctaaaat cattaaaagt ttcaatttct gtaaagattt acaatttctc
    17161 aaatacatta tgaatatgtg aaaaatttat tactacaata ctacatttaa aataagtatt
    17221 agtataaagg tattgttaca agtataaaga aatttatgta tactattgga ataaataata
    17281 ccttaaatta taattaagaa tagaactgtt aaataagaga tttgattatc atttgattat
    17341 agataatgta ctattaaaaa taaagtttaa tgaggagaaa aaatatgata agtatacata
    17401 aaaatatata tgatgataag ttatttgagg agctaaagat tgactgtaag aagtgttttg
    17461 gactttgttg tgtagctctt tatttttctg cgtcagacgg atttcctatt gataaggaat
    17521 caggaaaacc ctgtatgaat ttacaaccag attttaaatg ttctgtacat gataatctta
    17581 tgaaacgagg ttttaagggt tgtactgcat atgattgttt tggtgcgggt caaaaagtag
    17641 cacaagtaac atacaagggt atagactgga tgcaatcacc agaactagca aatcaaatgt
    17701 ctgaagtatt tttaattatg agacaactac atgaaatgtt atggtatctt aaagaagcat
    17761 ctgtattaaa tatatcagat acaatcaaat caaaaattaa tttaagaatc gaagaaactg
    17821 aaaagataac caatatgagt tcagaacaga tagttgattt ggatatcata tcacatagag
    17881 aaaaagttaa ttcattatta ttgcaagcga gtgagtctgt gatgggaaag gttaaatcct
    17941 ttatcaaaac ctctactctt aaaaacatga aaaaattaag caaaaatata gatttaatag
    18001 gagcagacct tagaaaaaca aatctaatag gagcagattt aagaggtaga tttctaatag
    18061 cagcaaattt aagaaataca gatttgagtg gggcaaattt aataggagca gacttaagag
    18121 attgtgatat tagaggtgct aatcttgaaa atagtatatt tttaacacaa ttacaagtta
    18181 atactgcaaa aggagattct agtacaaagt tgccagtttc actaatacgt cctaaatact
    18241 ggggaaaata attaaattaa tacataattt tacaaaatat gaactttttt gaccttgatt
    18301 catattatac attagagatt ctttataaga atttcttaat ataatatagg gagagatata
    18361 aaaatgagtt atcaaaatta taaatgtgaa agagattatg tgtatgatga ttataaatac
    18421 aataagtgta acgagtacta taatgattat gaggaaatga cacatgttca tgaatattca
    18481 gaaagtgtta agttagcaga agaatgtgag gatagacata accaccgtgc agcaggagtt
    18541 actggtgaag ttataccaat aaatggaggt acaaatcatg ttcataaaat aaatgataat
    18601 gtagatttcc ttgaccattt ccataagata tgtgttacaa cagggccagc aattagaata
    18661 cctggaactg ataaacacat tcacttaata tgtggagaaa ctactgttaa tgatggtcat
    18721 tgccataaat tcctttttac tactcaaata gaagctcctt tagtataagc tgatgtgaac
    18781 tattgtagta aatttgctag attatagtat ataaatgtta aaaatatata atagataata
    18841 tttaaactta atgaggacta tgatatttaa ccttcgtagt cctttctaag ttttgtataa
    18901 agaagtgtta tacaattaaa agtgatatag ggaggaaatt tttatgaaat ctggaataat
    18961 tcttgaaatg aaacagataa attcaacaga atatgacgaa atgttgcaag tctgggaatc
    19021 gtcagtaaga gcaactcatg attttttaac agaaaaagat attaaatttt tgataccatt
    19081 agttgaaatt ggacttaaag aagtagaaaa tatagtttgt ataaaagata atgatataat
    19141 aaagggcttt ataggaatag ataaagataa aattgagatg ctctttatag aagataaata
    19201 tagaggaaat ggtattggta aaaaattaat aaaatatgct atagataaat acaatgtaaa
    19261 atatgttgat gtaaatgagc agaataaaaa agctgtagga ttttatattc atttagggtt
    19321 taaagcgttc gataggtctg aaatagatgg acaaggtaac ccatttccaa tactacatat
    19381 gaaattaatt taaagtgata cttctcactt attcgcaaaa atatttactt aaatttttta
    19441 tacaaataaa agtcgtgaca gtcttaggac acgacttttt tactacacta ttaaattgaa
    19501 atttatctgt tctatattat gattattaga tgtagttttt ttattttaac tatgtactta
    19561 aataccaagt atacccatac ctatcaagta cttcagcagc accatcattt tgatgtggtg
    19621 gtgggtgtgg taaaaattct tgtacaagcg taccaccctc ggcaagtttt atagatattt
    19681 cttctatcgt ttctcgagat ggtagaacaa cacaaatcgc catgccagaa attacaacag
    19741 gcttgtctgt atccgcaccc attatacaac cttcatattt tgtgaaagta acacttgcgt
    19801 gcataacagg attgtttgga ttgctttcta atcgtgcaaa tatagttttt cctcctccga
    19861 aagcctcagc ataaaaatta aatgcttttt cacaagtacc attaaatatt aaatatggag
    19921 ttagcatgac aaatatatcc tccttgatat agaataattt atagttgcac ctgataatct
    19981 aaattctgat ttagtaaatt gtatcatagg gaaaccttga tgtatataat tttttattat
    20041 tagattatac aaatctatta atttaaaaaa atgttatatg taaggaaggt ttataggata
    20101 aaatataata aaaagagtaa ggtgacatta taaaaaatgt atattgacat tgacgctacg
    20161 taattgtata tactttgtct taaaggagat ggtaaatatg aatattatag aaattcgctc
    20221 agataaaata tacaagaaga taatggatgc accaataaac aaaaaagaag atatatacat
    20281 atatgaattg atgaagcctt ttgaatttaa gtggaagtgt atgaatgttc caatagttgc
    20341 taaacaaaaa ggcggatatg atgtaattat agcaagtgaa atgttaggag ttttatcgcc
    20401 taaggatatt gatgaaaagc aaaaaaagaa cataaatatg ttatctactg ataaaatttg
    20461 gaacacttgc aaagaaacca tagaaaactc tataaatgct tttataaaag aagggtatga
    20521 tttaaatatt aaggattata aatattcaat attattagct aatccaaata gtccttatac
    20581 aatattaagt gatggatatt ggggtgatgg tgggattcct ggatatatat ttctatcatt
    20641 ggttcctaat gaatatacta tcaatagatt accagtatta atagcacatg aatgtaatca
    20701 caatattaga ttccagttta tagagtggaa taataatata acattagaag aaatgatgat
    20761 aaatgaaggt attgcagaaa attttgcaaa atggatgttt ggagaggaaa tggtaggacc
    20821 ttgggtcagt agaacagata tcgaaacact aaacacttat ataaagccaa taataaaaag
    20881 tgctttaaaa gaaactggat ttcaaaatat aacatcttat ctttatggtg atgacatagc
    20941 taaaatgcaa ggatattttc cagtagggtt gccttattgt gcaggatatg cttgtggata
    21001 ttatatgatt aagtattatt tagaaaagac aaataaatca ataatcgaag ctactttatt
    21061 gccttatagt gagataatag aagcagtaga agagttttgg gaataaattt tattaattgc
    21121 atgatttgaa ataaatcatg caattatttt atttttaaga aaaaataaat tgacaataaa
    21181 ttataagaaa tatacaataa tatatataaa gaaatatttc aatatgtaaa agttttaaga
    21241 tttcatatc
//
LOCUS       DBGJFK010000071        20769 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.071, whole genome shotgun sequence.
ACCESSION   DBGJFK010000071 DBGJFK010000000
VERSION     DBGJFK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20769
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.071"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            78..1031
                     /locus_tag="ACOIAP_002881"
     CDS             78..1031
                     /locus_tag="ACOIAP_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGZ2639760.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RVPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFMFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            1021..1977
                     /locus_tag="ACOIAP_002882"
     CDS             1021..1977
                     /locus_tag="ACOIAP_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGZ2639761.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFVIYGIDINHLEYALSQRIPKI
                     FAMILGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAIMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKVVKKMIILIAILVSISTALIGPMTFLGLLLANIAREIFKTYKHTYLILGSMLIGM
                     ITLITGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            1974..2729
                     /locus_tag="ACOIAP_002883"
     CDS             1974..2729
                     /locus_tag="ACOIAP_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639762.1"
                     /translation="MIEIKNIFKKYKNKNVVDDVSFNIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMDFKIKNINGNRICIYF"
     gene            2821..3786
                     /locus_tag="ACOIAP_002884"
     CDS             2821..3786
                     /locus_tag="ACOIAP_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2639763.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKNNESKTSENSNNTIKIIH
                     NLGETDVKLNPKKVVVFDYSALDTMDTLGVAENLVGLPKASLPASLEKYKDEKYADLG
                     GLKEPDLEGIKSTNPDLIIINGRQEDFYEQLSKIAPTISTSKDDKEYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFKNKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDIKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            4240..6099
                     /locus_tag="ACOIAP_002885"
     CDS             4240..6099
                     /locus_tag="ACOIAP_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HGZ2639764.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHKPNDELIEYIDEILQELITGHGNYGLVLTDCNKYNEDLLLLEKKW
                     EDLNSEIKKVRMKEPNNQLLSISEEFFSLANDTVFEIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMIKLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICMHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YIDKEDLVVRQRIVDSELINTTNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHNQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQNHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDALKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIEYEEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS"
     gene            complement(6299..6898)
                     /locus_tag="ACOIAP_002886"
     CDS             complement(6299..6898)
                     /locus_tag="ACOIAP_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HGZ2639765.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNAQGENLRIN
                     GNKIKEIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(7001..7798)
                     /locus_tag="ACOIAP_002887"
     CDS             complement(7001..7798)
                     /locus_tag="ACOIAP_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2639766.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(7911..8016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(8108..9094)
                     /locus_tag="ACOIAP_002888"
     CDS             complement(8108..9094)
                     /locus_tag="ACOIAP_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGZ2639767.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMNYLSKTNTDNTNYCLSELD
                     IEQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVSFVENKLIGIRHEENALRNTLNSIEINDYFLGADTDILVSGILGVK"
     regulatory      9258..9434
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            9578..11308
                     /locus_tag="ACOIAP_002889"
     CDS             9578..11308
                     /locus_tag="ACOIAP_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HGZ2639768.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIIISALLLKEFGPMRKAEIKSRSRKIDI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGEDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVIKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKR
                     VDEAEIELVE"
     gene            11418..11498
                     /locus_tag="ACOIAP_002890"
     tRNA            11418..11498
                     /locus_tag="ACOIAP_002890"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11452..11454,aa:Leu,seq:tag)
     regulatory      12277..12381
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12591..15065
                     /gene="gcvPA"
                     /locus_tag="ACOIAP_002891"
     CDS             12591..15065
                     /gene="gcvPA"
                     /locus_tag="ACOIAP_002891"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HGZ2639769.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHDMVRK
                     SAGIFDVSHMGEVQIKGVESEKFIQNLVTNDISTLNINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSERYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSVKVCGCPCLVSRTGYTGEDGFEIYCENKYAEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPVEGGLSIFVKTNKESFIGKSILSK
                     EKENGAKRKLVGFEMQGKGMPRNGYDIRIGDKIVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIAKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATSAIEACIMAMNQTRKNKIVVSKTTHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDTEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAIQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            15065..16522
                     /gene="gcvPB"
                     /locus_tag="ACOIAP_002892"
     CDS             15065..16522
                     /gene="gcvPB"
                     /locus_tag="ACOIAP_002892"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HGZ2639770.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQNMIRKSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLSEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGNMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVSFLPIPVIEKREDKYILNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIDAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            16940..19297
                     /locus_tag="ACOIAP_002893"
     CDS             16940..19297
                     /locus_tag="ACOIAP_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HGZ2639771.1"
                     /translation="MGNLNLKRYNCDIKMGLSSEQIQSRIDNNLVNVFDNGKTKTYKQ
                     IFKDNVFTLFNLINIILVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIRDKEKKEIDVQELVLDDIMILKTGNQICADSKVLDGRLEVNESLITGE
                     SDIVIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKVVGIIIIPLGLILFAKQHFGNGDSIVTSIVGTVAAVNGMIPEGLTLLTSIALAL
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDVVMLEELDIDDIMG
                     NICNALKDDNATLNAIRDKYSILDTHKVKNLIPFSSERKYSGVIFEGEGTYLLGAFEF
                     IFKDKYKELKTEVEKYSKKGNRVIVLAHSNSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPMTVSEVARKAGLKTAGNFIDATTLKNDEDIYEAVDK
                     YNVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRTASLFLVKTIFSFFLSILTLFFFSRQYPF
                     VPIQLALIGAVTVGIPSFFLALEANRGRISGNFLLNILKNALPGALCVTINVIIVYNI
                     VEYLGYNSSVFSTMCAILTGVCGLLILRQQCLPFNKERIFLIVSMTIAFIVGILFLGG
                     LFSFVALSKQLILITVVLAVLMPIMIKVMRFVLDEILGAIVPNLN"
     gene            complement(19382..19699)
                     /locus_tag="ACOIAP_002894"
     CDS             complement(19382..19699)
                     /locus_tag="ACOIAP_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HGZ2639772.1"
                     /translation="MNEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEILAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
     gene            complement(20231..>20769)
                     /locus_tag="ACOIAP_002895"
     CDS             complement(20231..>20769)
                     /locus_tag="ACOIAP_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2639773.1"
                     /translation="LWRISKTYFSMQNSMKQEPCDFSHGRFRRENNVMAVHCPASNFN
                     VGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKLYWVNSGKKYNFLS
                     LSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSDLNHDNYSILERLERFIYVGDD
                     RNIIHRYVCGKLIEEPNI"
BASE COUNT         7988 a         2378 c         3332 g         7071 t
ORIGIN      
        1 ttattattga taaactattg aagtgaaaat gataataatt ttcattttaa ttaataaaag
       61 atttttaagg agggagaatg aaaaaaaggt atttagtcat aggaataata attttatctt
      121 atttttcttt atttatagga gctgaagata taaatataat gcatatattt gcaaaaaatc
      181 aacataagct tatgatattt atcatgagta gagtaccaag attaataagt atattgattg
      241 ctggtgtagg aatgagcata gcaggtctta taatgcaaca gataagtaaa aataaatttg
      301 tatcacctac aacaggagct acaatagacg cagctcaatt tgggatagtg atatgtatgc
      361 ttttagtacc aactgcctct atttttacaa agacaataat agcatttgta ttttctcttg
      421 tagggacttt tatgtttatg aaaataatag gtaagttaca atttaaaaat ataatctttg
      481 taccattagt aggtataatg tttggaaata taataggttc tatgacagat tttatagcat
      541 ataaatacga tttgagtcaa aatgttagct cttggatgca gggtgacttt tctatgatac
      601 ttaaaggaaa ttatgagata ttatatataa caatacccct tataatacta gcatatattt
      661 atgcaaacaa atttactgtt gttggtatgg gtatggattt tgcaacaaac ttaggtctta
      721 gttacaaaag aattgtcaat ataggtctga taatagtagc acttgttaca gtatgtgtag
      781 ttgttacagc tggtaatata ccttttatag gtctaatagt tccaaatatc gtatctttat
      841 atatgggcga taatataaga gcaagtatat ggtatacagg tttacttgga gctatatttg
      901 tacttatatg tgatattttt ggaagaatta ttatttatcc atatgaaata tctataggac
      961 ttacagttgg agttatagga agtatactat tcctttattt aatattaagg aggaatgtaa
     1021 atgaagctta gtctcaatca aaaaatttac tttgtaagta tattactatt catatcaata
     1081 gcactttttg taatttatgg aatagatata aatcatttag aatatgcatt atcacaaaga
     1141 ataccaaaaa tatttgctat gatattgggt ggaggatgta tagcatttac tactgtagtg
     1201 tttcaaacaa ttacaaacaa tcaaatatta acaccaagtg tactaggttt agattcatta
     1261 tatgtaatga ttcaaactat aatagtattt atatttggtt caagtagtag tctgattata
     1321 aatgaaaatt ataattttat tattaatgta gctattatga ttggagcttc attattatta
     1381 tataagatgc tatttgaaaa aaataaaaat aatattttct ttttaatcct agtaggaatg
     1441 atatttggaa ctttatttaa aagtgcaaca acatttattc aagtaatgat agacccaaat
     1501 gaatttttag ctttgcaaac tagcataatg gccagtttaa acaatataaa cactaatgta
     1561 ttgttaatag catttataat aattattgcc ataatacctt ttatatatga tgaaataaag
     1621 tatttagatg tattgtcatt aggtaaagag caagcaatta atttaggtgt agattttgat
     1681 aaagtagtta aaaaaatgat aatattaata gcaattttag tctcaatatc aacagcactt
     1741 attggaccta tgacattttt aggactttta cttgccaata tagccagaga aatttttaaa
     1801 acatataaac atacatactt gattttgggc tctatgttga taggaatgat tacattgata
     1861 acaggtcaat tttttataca acatgtattt aaatttgata caactttaag tgtagtaata
     1921 aattttatag gaggaattta ctttattcaa ttactattaa agggggcaaa tagatgatag
     1981 agataaaaaa tatatttaaa aaatataaga ataaaaatgt tgtagatgat gtctctttta
     2041 atatagaaaa aggaaagata acatctttta taggaccaaa tggagctggg aaaagcacag
     2101 tactatcaat agttacaagg cttataggag gtgatggtgg agaagtaata atagaaggaa
     2161 aaagcttgac taattatagc aataaagaat tggcaaaaaa aatagctatt cttaagcaat
     2221 ctaacaatat aactttaaag cttacaataa gagaattagt tggatttgga agatttccat
     2281 atagtgaagg taatctaact aaagaggatg aaaattatat tgatgaagca atagaatata
     2341 tgaaattgac tgatatacaa cacaagtatt tagatgaatt aagtggaggt caaagacaaa
     2401 gagcttatat agcaatggta atagctcaag atacagagta catattgctt gatgaaccac
     2461 tcaacaattt ggatatgaac cattcagtac agatgatgaa agtacttaga ggtctttgtg
     2521 atgagttaga taagactata gtattagtaa tgcatgatat aaattttgca tcatgttatt
     2581 cagataatat agttgcatta aaaaatggaa aagttgaaaa agtaggtcgt acagatgaga
     2641 tagtaaatga aaaagtttta gaagatattt atgagatgga ttttaaaatt aagaatataa
     2701 atggaaatcg aatttgtatt tatttttaaa atattatata taaaaataaa cttgctatat
     2761 tattttttat aaaattttta aagtaaaata aagattaata gaaaagagga aaatattgat
     2821 atgaataaaa aagcagcgat agtagcagca gtagctatta taggtttagt gacagtgttt
     2881 gcattaggtg gaagtaaaaa taatgagtcg aaaacatcag aaaattcaaa taatactata
     2941 aagataattc ataacttggg agaaacagat gtaaaattaa atcctaaaaa ggtagtagta
     3001 tttgattatt cggctctaga tacaatggat acattaggtg tagctgagaa tttagtagga
     3061 cttccaaagg cgagtttacc agcatcctta gaaaaatata aggatgagaa gtatgcagat
     3121 ttaggaggtt taaaagaacc agatttagaa ggtataaagt caacaaatcc agatttaatt
     3181 ataataaatg gaagacaaga agatttttat gagcaattgt caaaaatagc accaacaata
     3241 agcacaagta aagatgataa ggagtactta gaatctgtta aaaataatat agataaaata
     3301 gcaaaaatat ttggagtaga agaaaaagca aatcaagaat ttagtaaaat tgaaaagaaa
     3361 atagaaactt tgaataaaaa agtaacagat aaaaatttaa atgctttaac tataatggtg
     3421 aatgaaggta atttaagtgt atttggtgaa gaatcaagat ttagtatatt atacaatagt
     3481 tttggattta aaaataaaga taaaaatata aaagaatcaa gtcatggaca aaatattact
     3541 tttgagtata tagctaaaca aaatccagaa gttatgttcg ttatagatag aggaatagct
     3601 actggtagtg atataaaaga gagctcaact gcaaaatctg ttttgaacaa tgatataata
     3661 aaatctatgg atgcatataa aaatgataat ataatatatt tagattcacc aacatggtat
     3721 gtaaatgatg gtggtctaac atctttaaat aaaatgatag atgatgcttc aaaagcggtg
     3781 aattaataat ctgatataat caaaatgtgt tttttatgaa atgattatca aataaactag
     3841 gagttcttaa gaactcctag tttatttttt gcataataaa gatatagttt aaaaaataat
     3901 attatttaca ataagataaa tttattcaaa atctaataaa atatgaagtt atactagaca
     3961 aaaagaataa ttcttaaata taattaaatt atatggaata tataataata taattttaat
     4021 aagttgttta taatatataa attatattaa tagtaataat ttatatatta tgagaaattt
     4081 ttgtatatat agagcactct aaagatgaac tatgtaaaac aaggtttata tattctaatt
     4141 gtgtagaaaa ttttattgga aatgaatgca tattattaga aaaatagttt agagatatcc
     4201 aataaacata aaaaataata taggggataa gggtgtttta tgaagagatt tttgaggaga
     4261 attatcttag ttttatttat tttattgatt tttataagtt tcatttctat taaattaatt
     4321 cataatgttg gagattatgg gaaactgatt aattatgttg gtattgttcg tggagctagc
     4381 caacgcctaa ctaaactaga gatgaatcat aaaccaaatg atgaattaat agaatatatt
     4441 gatgaaattt tacaggaact gattacaggt catggaaatt atggcttagt actcactgat
     4501 tgtaataagt ataatgagga cttgctttta ttggaaaaaa agtgggaaga tttaaatagt
     4561 gaaattaaaa aagtaagaat gaaagaacca aataaccagt tattaagtat aagtgaagag
     4621 tttttttctc ttgcaaatga tacagtgttt gaaatagaaa acttttctaa agaaaaaagt
     4681 aattacttaa tgactttaat aataattata tctattatag gcatattagc atgtatcata
     4741 ttgattttac agtatagtaa aaaaatgatt aaattagaaa aattaaatgt agatttaaaa
     4801 aatattgcat ataaagatga actaacagga gtaaatacta tagaaaaatt taaattggat
     4861 gcaaatcaaa atatttgtat gcataaggat aagaaatttg ctgtgttcta tattgatttt
     4921 gaaaacttta aatacattaa tgatatattt ggatatgatt atggtgacat gatactgaaa
     4981 agatatgcta atcttatgat gaatgatata ggaaaatatg aaatatttgc aagagaaata
     5041 gcagatagat ttgttgcatt aagatgctat atagataagg aagatttagt agtaagacaa
     5101 cgaattgtag atagtgaact gattaataca acaaatgaga ttaaaaataa acatagcatt
     5161 actgttgtta gtggaatttg ctgtattgaa gatgtaaatg aaaaattaag tatagatggc
     5221 ttaataaata gagcgaactt tgcacaaaaa actgttaaga ataaaccagg tactaattat
     5281 gctttttata atgatagtat tcgtaaaaaa atgattgaag aaaatactat caagagtaga
     5341 atacatgaag ctattgaaaa aagagaattt atagtttatt tacagcctaa agtcaattta
     5401 cataatcaaa aaataaattg tgcagaagcc ttagttcgtt ggttgactcc agacaaaggt
     5461 attatatctc cagcaatatt tattccagta ttagaaaaga atttttttat tgctttagta
     5521 gataaatatg tttttgagga agtttgcaaa tggattagaa agagattaga tgaaaataaa
     5581 ccttttgttc agatatcagt taatgtttcc agaatacaat tttataatac taagttcgta
     5641 gaaacttatt ccaatataca aaataaatac aggataccta aaaatactat agaaattgaa
     5701 tttacagaga gtgttgcttt tgagaatcaa aatcatcttt tggaaattat acatgacttg
     5761 cacgaaaatg gatttacttg ttctttagat gattttggaa aaggttattc gtctttaagt
     5821 gttttaaaag atttgccatt tgatgcttta aagcttgact ctatgttttt caaggctagt
     5881 ttagataaag ataaagaaaa aatagtaata aaaaatattg tacatatgtt aaaggagctt
     5941 aatatcacaa ctgttgctga gggtattgaa tatgaggaac aagttgaatt tcttagggat
     6001 attgggtgtg atttagttca gggatttgta ttttataaac caatgccgat attagagttt
     6061 gaagaaatat tggataaaga gtttgtttat aatagctaaa atgtactttg taaaatacaa
     6121 actaattaag taaaattatt ctacactgaa caaattttca ttttatttac catataagaa
     6181 tgcgtaatga tataagtatt tgaaaagcca ccattatatg aaaattaaaa agaaaataaa
     6241 taatttttcg ataaaaaaga gactatgaga aaagtcaccc atagtctcct aaatatagtt
     6301 attttcttcc tgcaacccat tttaagcccc aatgaaattc agtatccatt tctctatgac
     6361 ctttgaagta tttaactact ttttcaacac taaatgtctc atcatttaca ttttctatca
     6421 atgctattga acacatatta tagccatttt tatgttcatc aagtttgaca actaagtctg
     6481 aatcttgttt ttgtttgatt gttacaattc catcagcttc agaccagtta gccacacctt
     6541 catatataaa agcataaata agtattcttt ttatctcttt tattttatta ccatttattc
     6601 ttaaattttc tccttgtgca ttacttcctg ttcggtcatc tccatctaat tgagcaaaag
     6661 gtggattgtc taaactacca aaagcatttc ctaatgcttg aacagcacct tttacaccat
     6721 ttttcatctc aaataggcaa cccaaatcta aatctatatt actgcttctt aaagagccaa
     6781 aaaaaccctt tttttgtact ttttgattcc aatttaaatt aactaagatt tcacctaaat
     6841 cgctattttc cttttttgta aggtttattt tttgtccctt ttttaattct atagccatag
     6901 taatcttcct ccacaaacat agatttattt aaatggtagc acttaataag tcaatattca
     6961 acaagattag aataataata ttaaaattat actaaatata ctaaaaagta ggaattacaa
     7021 tacctttgta tttttcttca attaagcttc ttgctttatc tgatgtaaga acatcttgta
     7081 gaactttaat cttttcacta tctttatctt cagttctaaa tgctaaaaga tttgcatact
     7141 catcatttat aggagctgta taaattccgt ttttcttggc atcaagacca gcaggtacag
     7201 cataagtagt atctataaat gcagcagtta catctggaag agaagatgga atttgagcaa
     7261 tatctaactc tttgaattgt attccctttg gattttctat tatgtcctta gggctaacta
     7321 atccatcacc tttaggcaat gttaaaagtc caatactttc aaggtatcta aggttcttag
     7381 aacaagaaga aggattattg cttattgcaa ttgtatcacc ttttttaaat tcatcaacag
     7441 attttatctt ataagagtaa agtattgctg ggcatacata tagtttttta ccagccatta
     7501 ttttgtaacc tttggcctta acagcttctt ttagataagg ttcatgttga aatagatttg
     7561 catcaatctc accattattt aaagcttcgt ttggaagtat gtaatcatca aagtttttaa
     7621 cctctaaagt atatcctttt tccttaataa gtggttttaa ttcttctaat aactctccac
     7681 ctggaactaa agtagcacca acaacaattt ttttatcatc tttagcttta gaacatccaa
     7741 ccacagctaa agttaatact agacataata ataaacataa taattttttg aatttcatat
     7801 aaattccctc ctgaatataa ttgattagtt aaaaataaaa tactattctt tatcagactg
     7861 caaaataaaa ataagcctga gtttaaactc aggctttaaa agctaattta gactcatctt
     7921 tcagtataat actgcaggat ttagcaccaa tgtatataaa aatatactgg ttgctgggtt
     7981 tcatagggcc agtcccttca ccactctgga taagaagtat caatttttaa ttatgttata
     8041 aatattatca tgatttttta cgtctgtaaa tataatttta taaatatttt aaaatcttta
     8101 gtgtatttta tttaacacct aaaattccag aaactagaat atcagtatca gcacctaaga
     8161 aatagtcgtt tatttcaata gaatttaggg tgtttctcaa agcattttct tcatgtctta
     8221 tgccaataag tttattttct acaaatgaaa catcacattt tccaaaaaaa tctccaaaaa
     8281 attttatgct agttattatg cctttatcaa catttaaatt aaactcaaca tttccaccag
     8341 aatattttaa ttcatttgaa agagtatatt ttggtgaatt accaaaattc caatcccaag
     8401 tttcatattt tgatttagta agcttttcta tttgttctat atcaagttca ctcaaacaat
     8461 aattagtatt atcagtgttt gttttagaaa gatagttcat tatagcatct ttaaattcta
     8521 atatgtccat tttagagtgt aaatgttcac ttatattggt tacacgagat tttacagatt
     8581 ttattccttt tccttcaaat tttataggtt taacttttaa tgcttttgag aggtcattta
     8641 tttcagatga aaataaaagt gtaccatgat gcattacttt gtttttgtag ttgtactgag
     8701 catttccaga aaatttcttg ccgtctataa gaaggtcatt tcttccagaa aattcagcat
     8761 tgacatctaa tgttttaagt aagtctatta ttggttgagt gaatcttctg aaatcactaa
     8821 aattattatt gttacaagct ataaatgtaa aatttatatt tcctaaatca tgaaatacag
     8881 ccccaccacc agactgtctc ctaacgacag gtatagaata ttcttttata tattctaaat
     8941 ttatttcaga aagtgtgttt tggttttttc caacaattat agaaggttca ttcctccata
     9001 aaatgaatag gtcttcatca aaatttttta gaagatattc ttccattgct aaattaaaat
     9061 aagggtttgt tttttcatta taaattaata acattaaagt agttcctcca tataattgat
     9121 aaaattttta ttatgagtac aattaatttt ataattcgac aataatgtaa aaactccttt
     9181 aaattagaaa ttttaaaaac taccttgcaa agtttaaata aataatatat actcaaaata
     9241 tgtttaataa aagtgaatag aagggtagag gcgcaataat ctatcagtac taataaggag
     9301 ttaagcacat agagttatta ggaaaggaga tattgccgaa gttttataat cgatgcttta
     9361 agattatatt gctgggggta catagaaaat atgtacaact gtcacaggtt tatttgtggt
     9421 gagctatcat ttaaggaatt atattatatt tatttttact attgttgata tattgtaatg
     9481 tttaagcctt gagtgtttac cactcaaggc ttttttagtt ttattgtaac ataataccct
     9541 atacagttca caaaattaaa aggagaggga gatttatatg aggaacaaaa aaattaatat
     9601 tatttttctg acgacaatca tgttcataat gtcaacagta atggtttttg cagaagagga
     9661 tatagacact attgcactag ctaatgcaga aaaatttgga attttaactt taataccacc
     9721 attagttgct ataatacttg catttataac taaaaacgta ataatttctt tacttatagg
     9781 tattctttct ggtagtttta taattaaagc tagtggtatt aatgtttttg cgacatttat
     9841 acaagcattt ttagatttag tagacagagc tttagtatct ttagcagacc cttggaatgc
     9901 aggaataata ctacaggttt tggcaattgg aggagtaata aatcttgttg ctaaaatggg
     9961 aggagctaaa gctatagctg aagcacttgc taaaagagca aagtcagcaa aagggacaca
    10021 gcttataaca tggtttttgg ggcttttagt attctttgat gattatgcca attcattaat
    10081 agtaggtcct atgatgagac ctgttgcaga taagatgaaa atatcaagag aaaaactagc
    10141 ctttataata gatgctacag cagcaccagt agctggttta gctataatat ctacatggat
    10201 aggtcttgag gttggtttaa tacatgatgc ttttgaaagt ataagtatag atgtagatgc
    10261 atttggtata tttttaaata caataccatt tagattttac aatatattaa tattagcatt
    10321 cattataata tcagccttat tattaaaaga atttggacca atgagaaaag ctgaaataaa
    10381 atctagaagt agaaaaattg atatagacct tgatgaaggc gtagaagagt tggatgattt
    10441 ggctccaaaa aatggagtga aattgagtgt atggaatgct ataatcccaa taggaacttt
    10501 gataatagtt gcattagcat cattttatta tagtggatac acatctataa tgggaggaga
    10561 ggataaggct ctgatacaac tatttacaaa ttctccatat tcttttgaag caataaaaga
    10621 agcatttagt gcatctgatg catctagagc attattccag tctgcacttg ttgcaagttt
    10681 agttgctatt ataatggctg taataaaaaa gatttttaca atatcagaag caattgatgt
    10741 ttggatagat ggaatgaaaa gtttagtaat cactggtgta atattaatac ttgcatggtc
    10801 attaagttca gtaataaaag agttaggtac agctaaattt ttaatacatt tattgtcagg
    10861 ttcactacca ccattcttat taccaagttt aatatttggt ttaggagcaa taatatcttt
    10921 tgctactgga acagcttatg gaacaatggg tatacttatg ccacttgcaa taccattagc
    10981 atactcatta aatcctgata tgtcttatgt aatagtaagt actagtgcag ttttaacagg
    11041 tgcaatattt ggagaccatt gttctccaat ttcagataca acaatacttt cttcaatggg
    11101 agctgggtgt aatcatatag accatgtcaa cactcaaatg ccatatgcta tatttacagc
    11161 agtaattact attgtatttg ggtatatacc agctggactt ggattgccaa tatatatagt
    11221 attaccagtt gcaatagctg ctatatttgt aggtattcaa ataattggta agagagtaga
    11281 cgaagcggaa atagaacttg tagaataaag atataaataa gtttcacctt ttattatcat
    11341 tattttgtta gtttttagat aattttaaaa agttattgaa aataatagcg aaatatagta
    11401 aaataaaaga gtgataagcg gatgtggcgg aattggcaga cgcactagac ttaggatcta
    11461 gcgccattgg cgtgggggtt cgactccctt catccgcact ttacagtact taattgtgct
    11521 gaaaaaaact ggggttgctg gctttcggag tgggctatcc cgtttttatt ttttggtata
    11581 tatgaaagat tggcacttta atatgaagtg ctttttttat aggcaaaaaa cagtacattt
    11641 atttctgttt tattgtcatt aatttattag aacatgcttt agttaagaat atgttaataa
    11701 gcaatgttca cattcttgat aaaatatgga atatatgtat ctttactaag gcagaaatga
    11761 aataactaaa ctactaaatg atattataag atgataaata agtttcagtt tattggatgg
    11821 ttgaagtaat cagaaattgg aattttatag tcttaatata atgtatgaaa ttttatagca
    11881 atgtatttca taagtataaa gtgactaaaa ttttaaaaaa tatacaaatt ctatagaagc
    11941 taaataattt caactctatt ttaaaaatct tatttttcac aagtttaaaa ttgtaaacga
    12001 tttcatcaag tctatgaata tacttttaac atgttatagt aaatctcaat ataaatttac
    12061 atttgcttcc ttgtatgtta ttttaataat aaattaagtg aaaatgttat tttacattaa
    12121 tatataatat ttttgcataa gaatgaataa tataaaagcg aaataattga taataaaaac
    12181 ttaacaaaaa aattaataca taaaaaaaaa taaatataat gtgttgacat ttaattgaaa
    12241 tattcataca ataaaattga aaataaatat ttccaaatga gattagcgag agagtccttt
    12301 atacgaaaag gcgccgaaga agaaatttaa gaaatgccaa tttttagaga agctttcagg
    12361 caaaaatatc gctaattgat gggactctgg agagacttaa gttaagatac tataagtcac
    12421 cgaagaagca aaataatatt aaattattaa atctttcagg tatacaaaca gggatatata
    12481 ggctaggatt attttccatg ctgatatatc ttttttttat gaaaaagtac aggaaataat
    12541 atcaaagtta cttaaataca gtaggtctaa ttttataggg agggttatat atgaatgaat
    12601 tgaaaagagt atctttgtat aacatacaca aagagcttgg agcaaaactt gttgaatttg
    12661 ctggctggga aatgccttta gaatatgaag gtataaataa agagcatgat atggtcagaa
    12721 aaagtgcagg tatatttgat gtatctcata tgggagaggt acagataaag ggagtagagt
    12781 cagaaaaatt tatacaaaac ctagttacaa atgatataag cacattaaat ataaatgaca
    12841 ttatatatac acctatgtgt tatgaaaatg gtggagtagt tgatgattta ttaatatata
    12901 aatttggtga agaagattat ttattggtaa taaatgcagg caatatagat aaagatgtag
    12961 catggataat aaaacaaagt gaaagataca atgtagatat aaaaaatata tctagtgaag
    13021 tgagtcaatt agcaattcaa ggacctaaag cagaagaaat ccttcaaaaa atcacagata
    13081 tagacttaaa ctcaataaaa ttttataagt caattccatc agtaaaagta tgtggttgtc
    13141 cttgtttagt ttcaagaaca ggatatactg gggaagatgg gtttgagata tactgtgaaa
    13201 ataaatatgc agaaataatt tggaatgaag ttctaaaggt tggaggagaa gatatatgtc
    13261 cagctggact aggttgtagg gacactttga gatttgaagc agctctacct ctatatggac
    13321 atgaaataaa tgaacatata tctccggttg aaggtggttt atctatcttt gtgaaaacaa
    13381 ataaagaatc atttattggc aaatcaattt tatcaaaaga aaaagaaaat ggagccaaaa
    13441 gaaagttagt aggatttgaa atgcaaggta aaggaatgcc tagaaatgga tatgatataa
    13501 ggattggtga taaaatagtt ggatttgtaa caacaggatg tgcatctcca acaacaggaa
    13561 aaattttagg tatgggaatt atagattctg agtatgcaaa agtaggaaat gaaataggta
    13621 tagcaatcag gaaaaaagtt gttcctgctg tgatagctaa gaaacctttt tataaaaaac
    13681 aatataaaaa agataatatt atattaaaca aagaaaataa attttcatat atacctgcta
    13741 caagtgaaga taaatcaaaa atgttaaaag tagttggatt aaattcagtt gatgaattat
    13801 tttcagatat accagaagaa gtaaaattaa aaagagattt aaatttggaa attggaaaat
    13861 ctgaattaga ggtaagtaaa atagtaaaaa gattgtcaga agaaaatcta agcttagaag
    13921 acctgacttg ttttcttggt gctggtgcat atgaccatta tataccatca attataaaac
    13981 atataacgtc aagatctgaa ttttatacag catacactcc ataccaagct gaaataagtc
    14041 aaggaacttt acaagtagtt tttgaatttc aatctatgat tgcagaaatt acaggtatgg
    14101 aaattgcaaa tgcatcaatg tatgatggag caacttctgc aatagaagca tgtataatgg
    14161 caatgaatca gactagaaaa aataaaatag tggtgtcaaa aactactcat cctgaaactt
    14221 tgtcagtatt aagaacttat ttacaatata aagattgtga gatagtagaa attgattttt
    14281 gtaatgaata tgggactaca gatatagaaa aattaaaagc ttctgtagat aaagacacag
    14341 catgtgttct tatacagact cctaatttct ttggaattat tgaagaaatg gaagaaatag
    14401 aaaagataac tcatgaaaac aaggctatgt taattatgag tgtagaccca atatcattag
    14461 gagttttaaa aacaccaggt gagataggtg cagatattgt tgttggagaa gcccaatcac
    14521 ttggaaatcc tcttaatttt ggaggtcctt atgtaggatt tttagctagc aaatctaaat
    14581 atacgagaaa aatgccagga agaatagttg ggcaaagttt agatacagaa ggtaagattg
    14641 catatgtatt aactttacaa actagagaac agcatgtaag aagagaaaaa gcaacttcta
    14701 atatatgttc aaatcaagct ttaaatgctc ttgtggcttc aatatatatg gctactatgg
    14761 gtaaagaagg atttaaagag gttggtatgc agtctatgaa aaaagcacat tatacttata
    14821 ataagcttgt acaaactgga aaatataagc caatatttaa aggcaagttt ttcaaagaat
    14881 ttgctataca aggaaatctc aatatagaaa ctataaatga taaactccta gaagaaaata
    14941 tattaggtgg ttataattta gaatacaatt atccagaatt aaaaaattca actttacttt
    15001 gtgtgactga gaaaagaagc aaagaggaaa tagataagtt agttggaata atggaggggt
    15061 tataatgaaa gaatataata gtttattgat agatatatct aaaaaaggta gaaaagcata
    15121 ctcacttcca aaactagata tagatgatat aaaaatagaa gatatgattg accaaaatat
    15181 gataagaaaa agtgaattga atttgccaga agtcggtgaa ttagaattag ttagacatta
    15241 tacattatta tcaaataaaa actttggtgt tgatacaggt ttttatcctt tgggttcttg
    15301 tactatgaaa tataatccta aaataaatga agatatggca gcacttccaa actttactgg
    15361 aatgcatcca tatcaatctt cagatacagc tcaaggttct ctttccttga tgtatgattt
    15421 atcaagaaga ctttcagaaa ttacaggtat ggatgaagtt acactacaac cttcagcagg
    15481 ttcacatggt gagtttacag ggcttatgat tataaaagca tatcatgaaa atagaggtga
    15541 ccataagaga accaaagtga taattccaga ttctgcacat ggaacaaacc cagcaagtgc
    15601 agctatggca aactttgatg tgattcaaat agcatctgat aaaaatggag ctgtagacat
    15661 aaatgcatta aaagaagttt taaatgatga agtagcagct cttatgctta ctaatccaag
    15721 tactcttggt ttgtttgaaa aaaatataaa agaaatagct actcttgtac atgaagcagg
    15781 agggcttttg tactatgatg gtgcaaacat gaatgctatt atgggtataa caagacctgg
    15841 aaacatgggg tttgatgtgg ttcatcttaa tcttcataag actttttcta ctcctcatgg
    15901 aggtggggga ccaggagctg gtcctgttgg agttaaaaaa gagttggtat cctttttacc
    15961 aataccagta attgaaaaaa gagaagataa gtatatatta aattatgata gagaaaagtc
    16021 tattggaaaa attaaaaact tttatggtaa ttttggagtg cttgtaagag cttacactta
    16081 tatattaact atgggaagag atgggcttaa agaagctagt gaaatggcag ttttaaatgc
    16141 taattatata aaggaaagta taaaagatga ttatattttg ccaatagata ctttatgtaa
    16201 gcatgagttt gtattaggtg gattaccaag aggagaggca aatataaaaa ctattgatat
    16261 tgcaaaaaga ctactagatt atggatacca tcctccaaca atgtactttc ctcttattat
    16321 aaatgaggca cttatgatag agcccacaga aagtgagagt atagagacat tagatagctt
    16381 tatagacgct atgaaaagtg ttgctaaaga agcaaaggaa gaaccagaac tattgaaaac
    16441 tgctccacat aatactttag taaaaagggt agatgatgca agggcagtaa aaaaacctat
    16501 actgacatgg tcacaaagat aaataattaa aaaatagaga tttaaagcat aaataaattt
    16561 gaatttgcaa aaaaagctat ctaacttaat ctagtttagg tagttttttt gtattggtag
    16621 atataagatt ttctattaaa aatttaaatt atattattac tcatataaaa tattaatgta
    16681 atgcttatgt acaaatattc ataagaatta ttgagcttta ttttgcgata attctattta
    16741 ctttttaatt taagaaaaaa ttaactaaaa tatatcgaaa tttataaaaa tttagtaaat
    16801 cttaagaatt ataatattta aatctttaga tttatatttt attatataaa atatagaaga
    16861 aaaaaataaa aaaaatgata attttataat atatttataa ttttaagtat aaaaattgtt
    16921 aaattaaaag gagcagagta tgggtaatct taatttaaaa aggtataatt gtgatataaa
    16981 aatgggatta agtagtgaac aaattcaaag tagaatagat aataatttag ttaatgtatt
    17041 tgataacgga aaaactaaaa cgtataaaca aatttttaag gataatgtgt ttacactttt
    17101 taatctaata aatattattt tagtatgttt actagtttca gttggttctt ttaaaaatac
    17161 cttatttata tttattgctg taattaatac tattataggc gtaattcaag aaataagagc
    17221 taaaagattg ctcgacaatc tatctgttat agtttcaaat aaggtatctg ttataagaga
    17281 caaagaaaaa aaagagattg atgtacagga attggtacta gatgatatta tgattttaaa
    17341 aacaggaaat caaatttgtg cagattcaaa agttctagat ggaagattag aagtaaatga
    17401 gtctttaatt acaggagaat ctgatattgt cataaaaaac aaaggtgatt tcttatattc
    17461 tggtagcttt gtagtttctg gagaagcttt tgtaagagtt gaaaatatag gaaaagataa
    17521 ctatgcgaat aagatagcta atgatgccaa gatttctaaa aaacataatt ctcagcttag
    17581 aaattcatta aatgcaatat taaaagttgt aggtataata attattcccc tagggcttat
    17641 attatttgca aagcaacatt ttggaaatgg agattctata gttacctcta tagtaggaac
    17701 tgtggcagct gtaaatggaa tgataccaga aggactgaca ctacttacaa gtattgcact
    17761 ggctttagga actataaagc ttgcaagtca taaaacgtta gtacaagaat tatactgtgt
    17821 agaaactctt gctagggttg acacattatg ccttgataaa acaggcacta ttacagaggg
    17881 taaaatgcaa gttgatgatg tagtaatgtt agaggagtta gatattgatg atataatggg
    17941 aaatatatgt aatgctctta aggatgataa tgcaacacta aatgcgataa gagataaata
    18001 cagtatttta gatacacata aagttaaaaa tttaattcct ttttcatcag aaagaaaata
    18061 tagtggtgtc atatttgaag gtgaaggaac atatttacta ggagcatttg agtttatttt
    18121 taaggataaa tataaagagc ttaaaacaga agtagaaaaa tattctaaaa aaggcaatag
    18181 ggtaatagtt ttagctcata gtaattctta tatggaagac aacaatattc ctgaagacat
    18241 aaaaccacta gcatttatat taatattgga taaaattaga gatgaagcta aggaaacatt
    18301 agaatttttt tataatgaag gtgtagatat aaaaattata tctggagaca atccaatgac
    18361 agtaagtgaa gtggctagaa aagcaggtct taaaacggct ggtaatttta ttgatgcaac
    18421 aacacttaaa aatgatgaag atatatatga agcagttgat aaatataatg tttttggaag
    18481 ggtaagccca cagcagaaaa aacaaatgat tttagcattg aaaaaacaaa atcatacagt
    18541 agctatgact ggagatggtg taaatgatgt gctagcactt aaggaagctg attgtagtat
    18601 cgctatggct tctggaagtg atgttactaa aaatgtttct aatttggtat tgttggattc
    18661 aaattttgca tcaatgccaa aggttgttat ggaaggaaga aaggtaatta ataatattca
    18721 aagaacagct tctttatttt tagtaaagac aattttctca tttttcttgt cgatattaac
    18781 attatttttc tttagtagac aatatccatt tgtgcctata caactagctc taattggcgc
    18841 tgtaacagtg ggtataccat cattcttctt agctcttgaa gcaaatagag gtagaatttc
    18901 aggtaacttt ttactcaaca tattaaaaaa tgctttacca ggagcacttt gtgtgacaat
    18961 aaacgtaatt attgtttaca atatagttga atacttaggt tataattcaa gtgtattttc
    19021 tacaatgtgt gctatattaa ctggtgtgtg tggactttta atattaagac aacaatgttt
    19081 accatttaat aaagaaagaa tatttttaat tgtaagtatg actattgcat ttattgttgg
    19141 gattttattt ttaggtggat tattctcatt tgtagcattg agtaaacaat taattctcat
    19201 aactgtggta ctagcagtat taatgccaat aatgataaaa gtaatgagat tcgtattaga
    19261 tgagatacta ggtgcaatag ttccaaattt aaattagatt taataatata taaaaagagc
    19321 agtcttcatt gaactgctct ttttagatgt gtttaatttt atgtaagaat atgtagcttt
    19381 attaatcagc tatatatgag caacagtagt caacgacttc attaactttt aaatcaaaac
    19441 ttgaatcact aggaacatta aatttttgac cttctttata agttacaaac tcattgcttc
    19501 caggcaattt tacatccata cttccagcaa gtatttccat tatttcttct tctctagtag
    19561 aaaaagtata ttctcctggc aacattaatc ctaaagtttt tctctctcca ttaggtagta
    19621 ttattactct actgcttact ttaccatcaa aataaacgtt tgcctttttt actgcagtaa
    19681 cattcttaaa ttcattcatt agataaaacc tccaaaatta tttgtatata tacattatat
    19741 aaaaataata taaaaaatgc tatatattta caaataaatt tagtatttgt taaaaaaatt
    19801 aataaaaata aaaaatgagt aaaattactt aaattgataa aaatatgtaa aataaattaa
    19861 taattgtaaa agagaggagt tttatggcac atatgttttg atgatattta ttatttatta
    19921 aaagaaacaa tgaggttaaa attaatatca tataataaaa ttgtattact ttaaaacgat
    19981 ttatcaatag gtaaaattta tgaggtatga atacaataac aatatagttt tacgattgta
    20041 gatatcaaaa aatgtatgtt actagaaagg cgttttgtag atttatatat gatgtaatca
    20101 ttaaagctat aaataaacta aataaaaaga gtatgtttta acctacgctt ttagatttga
    20161 aatatactct tttattaatt atagttatac aaattaacca gattatatat aattaaaatt
    20221 tttataataa ttatatatta ggttcttcaa ttagttttcc acatacatat ctatgaatga
    20281 tatttctatc atcaccaaca tagataaatc tttcaagtct ttcaagtata gaataattgt
    20341 catgatttaa atctgaatca tcaataatca atgcatcaaa atcataacct tcctcaaagc
    20401 taccaacttt tccaaagaaa cttccaccac ttttggttgc aatataaaaa gcttcagata
    20461 aagacaagaa attgtacttc ttaccagagt taacccaata taatttagat aattgtattg
    20521 cagataccat tgctttaaat attgacaatg tatgcccacc acttatatct gaaccaagtg
    20581 ctaatctaat attattatcg attaattttc tgataggcat agcaccacta ccaacattaa
    20641 agttagaagc tggacagtga actgccataa cattgttttc tctcctgaac ctcccatgac
    20701 taaagtcaca gggttcctgc ttcatagaat tttgcatact aaaatatgtc ttactaattc
    20761 tccacaggc
//
LOCUS       DBGJFK010000072        20750 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.072, whole genome shotgun sequence.
ACCESSION   DBGJFK010000072 DBGJFK010000000
VERSION     DBGJFK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.072"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            376..1269
                     /locus_tag="ACOIAP_002896"
     CDS             376..1269
                     /locus_tag="ACOIAP_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HGZ2639774.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELKNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1269..2663
                     /gene="gltA"
                     /locus_tag="ACOIAP_002897"
     CDS             1269..2663
                     /gene="gltA"
                     /locus_tag="ACOIAP_002897"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HGZ2639775.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3028..5247
                     /locus_tag="ACOIAP_002898"
     CDS             3028..5247
                     /locus_tag="ACOIAP_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2639776.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIETSKRELENYLEINISLLKALSKDDRFSDSETSLIEKGKLLRPYQKEYNLFMIGI
                     TDTKGNTSSTYREKVGSIKDRPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIIKN
                     NEMIGTIFASFYFQDVNNLISRSNLDDSIKFLMIDKNYTIISHPNKKYVNDKSKILDL
                     EGNIIGTTKSEILKNINEKCQGKFLYWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFQ
                     SLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACSTEDELLNRLSKINKEICNLSTTNSSKYKIVMSSGIYKINKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEETRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LNDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLREIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5400..6146
                     /locus_tag="ACOIAP_002899"
     CDS             5400..6146
                     /locus_tag="ACOIAP_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639777.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIDKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVILDGYDISKLEGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDINIQTRNISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTKINIEQNVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6146..8026
                     /locus_tag="ACOIAP_002900"
     CDS             6146..8026
                     /locus_tag="ACOIAP_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639778.1"
                     /translation="MDFKKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     MKSGIQSGFTAFMALMTSELIILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTELYFPVKAILLTVVS
                     FMILFLITGPMSLKLLNKKSILELLLGTKKPKKEIKSSKLFGIAGIVCLILGYAMILF
                     GNKLKINGGMYTTTLLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLMYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGESSKNNFPMVYSYFSEHNNEKEYEE
                     LQKIRDTIKRYDYKELSFPILQYNREVLLNVKDYNKLSKELGLDKISSKLRKYEGIII
                     PSSNSQEHINSLKELRNYSIKNLNIKIKKSTNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKMNFHGFDYKNWQNSAKITENLKVKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEMEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFNLENLGILLLISSIYSLYFYLLKKFYTRKVWF
                     FD"
     gene            8145..9536
                     /locus_tag="ACOIAP_002901"
     CDS             8145..9536
                     /locus_tag="ACOIAP_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2639779.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAVLTIGYYIS
                     GKSNLRFSKSNLKLDTKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLAVATIILCMGMV
                     VIMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9643..10683
                     /locus_tag="ACOIAP_002902"
     CDS             9643..10683
                     /locus_tag="ACOIAP_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGZ2639780.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDESL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11175..11828
                     /locus_tag="ACOIAP_002903"
     CDS             11175..11828
                     /locus_tag="ACOIAP_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGZ2639781.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFIEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11904..12113
                     /locus_tag="ACOIAP_002904"
     CDS             11904..12113
                     /locus_tag="ACOIAP_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639782.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNVVMIDDGTGTLKQAIF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12253..12819)
                     /locus_tag="ACOIAP_002905"
     CDS             complement(12253..12819)
                     /locus_tag="ACOIAP_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGZ2639783.1"
                     /translation="MMNNELSTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNMPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDIAKK"
     gene            12979..13632
                     /locus_tag="ACOIAP_002906"
     CDS             12979..13632
                     /locus_tag="ACOIAP_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGZ2639784.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVSLHETSLL
                     MIISVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13790..13966)
                     /locus_tag="ACOIAP_002907"
     CDS             complement(13790..13966)
                     /locus_tag="ACOIAP_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639785.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
     gene            14493..15437
                     /locus_tag="ACOIAP_002908"
     CDS             14493..15437
                     /locus_tag="ACOIAP_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HGZ2639786.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFITINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGESSVEADREVVKLALKILEKYNNKFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNIHELKVYIEELKIKCEVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            15459..16085
                     /gene="hisG"
                     /locus_tag="ACOIAP_002909"
     CDS             15459..16085
                     /gene="hisG"
                     /locus_tag="ACOIAP_002909"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HGZ2639787.1"
                     /translation="MDYLTIALAKGRIEGESFKKLKKMGLGNSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            16119..17168
                     /gene="hisC"
                     /locus_tag="ACOIAP_002910"
     CDS             16119..17168
                     /gene="hisC"
                     /locus_tag="ACOIAP_002910"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HGZ2639788.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEIADS
                     NIDLNLYPEDSYSDLKESIIDYINISGVSKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVIDIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKRKDIKKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEERKILYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     AMFIGAIRDILKKEK"
     gene            17171..17749
                     /gene="hisB"
                     /locus_tag="ACOIAP_002911"
     CDS             17171..17749
                     /gene="hisB"
                     /locus_tag="ACOIAP_002911"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HGZ2639789.1"
                     /translation="MRIWNVERNTLETQISVELNIDGSGKAEIDTGIGFLDHMLTLMA
                     FHGKFDLKVICKGDTCVDDHHSVEDIGIAIGESFKNALGDKKGIRRYSNIYIPMDESL
                     SMVSIDISNRPYLVFNAKFDIQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            17751..18356
                     /gene="hisH"
                     /locus_tag="ACOIAP_002912"
     CDS             17751..18356
                     /gene="hisH"
                     /locus_tag="ACOIAP_002912"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HGZ2639790.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSNIDEIKQADSLILP
                     GVGAFRDSISALEKLGLIPIIKEHVSNGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELVAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            18353..19075
                     /gene="hisA"
                     /locus_tag="ACOIAP_002913"
     CDS             18353..19075
                     /gene="hisA"
                     /locus_tag="ACOIAP_002913"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HGZ2639791.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKINVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIDEIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAVENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEIVSDVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFNIYEKIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            19057..19815
                     /gene="hisF"
                     /locus_tag="ACOIAP_002914"
     CDS             19057..19815
                     /gene="hisF"
                     /locus_tag="ACOIAP_002914"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HGZ2639792.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERTTSLEFVTKVAENISIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKMEDFYQAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKNMGVEVRL"
     gene            19843..20511
                     /gene="hisIE"
                     /locus_tag="ACOIAP_002915"
     CDS             19843..20511
                     /gene="hisIE"
                     /locus_tag="ACOIAP_002915"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HGZ2639793.1"
                     /translation="MNNKCNDIYTDEVDEFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKEAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDTAKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         8266 a         1955 c         3624 g         6905 t
ORIGIN      
        1 agaaattagt gttattatga aaacctaagt taacttatta aataaataat tgaataaaaa
       61 aaatttatta tgtatttata aaatttttgt tacaaatttg gcataatata gtatacttta
      121 agtgtgtatt aggttaaatc tataacaaat tagacgtatg atatagactg agtgtttatt
      181 ggcatttaca agaaatttgt taatatcaac tatttgtagt ttgggcagtt ataattacta
      241 taggggggat gtccaataca aaacaatcaa ccaagaacta atattatatt ataaaaagtt
      301 atagttttgt gtgtttattt ttttaattaa atttaaagtg ggaaaaatat atttgttaga
      361 atggagaata gcgagatgag taataaaata gttagtaaga gacaattaac agatagtatt
      421 tatttaatgg aaatagaggc acctagagtt gcaaaatctt ctcaacctgg tcaatttata
      481 ataattaaaa atgacgaaaa aggagagagg attcctctta caatagctga ctatgataga
      541 gaaaaaggaa cagtaactat tgtattccaa acagttggtg cttcaactaa aaagttagca
      601 atgtttgaag aaaacgattt tgtaatggac tttgtaggac cactaggaca agcaagtgaa
      661 tttatacatg aagatataga agaattaaaa aataaaaaga tattatttgt agctggtgga
      721 gttggttctg ctccagttta tccacaagtt aaatggttta aagagcatgg tttagatgta
      781 gatgtaataa ttggtgcaag aactaaagaa ttaattatat tagaagatga tatgaaaaaa
      841 gtagctaaaa atgtatatgt atcaacagat gatggtacat atggatttaa tggaagagtt
      901 acagacctat taaaagattt agttgataat caaggtaaaa aatacgacca agcaatagta
      961 attggaccaa tgataatgat gaaatttatg tgccaattga ctaaagaact aaatatacct
     1021 actatagtaa gtttaaatac aataatgata gatggaacag gtatgtgtgg tggttgtaga
     1081 gttagcgttg gaaatgaaac taagtttgca tgtgtagatg gtcctgaatt tgatggtcat
     1141 ttagttgatt ttgatcaagc aatgagaaga caatctatgt acaagactca agagggaaga
     1201 gctatgctaa aacttgaaga aggcgatagt catcatcata gtaattgtgg atgtggaggt
     1261 aacaaataat ggatgctaaa aaagtaaaag taccagttag agagcaagaa cctgctgtta
     1321 gagcaacaaa ttttgatgaa gtatgtttag ggtataataa agaagaagct atggcagaag
     1381 ctaatagatg tttagcttgt aagaaaccta aatgtgtagg tggatgtcca gtaggaatcg
     1441 acataccagg gtttataaca aaaattaaag aagacgatat agaaggtgct gctaaagtaa
     1501 tagctaagag tagctcatta ccagccgttt gtggtagagt gtgtccacaa gaaagccaat
     1561 gtgaaggtgt atgtatactt ggaataaaat cagatgctgt atcaataggt aagttagaaa
     1621 gatttgtagc agattggtca aaagaaaatg acataaattt atctgataca gagcctaaga
     1681 aaaatcaaaa ggtagcagta ataggaagtg gtccagcagg tctagcttgt gctggtgact
     1741 tagctaaaaa aggctatgat gtaacaatct ttgaagcaat gcatgagcca ggtggagttt
     1801 taacttatgg aatacctgaa tttagacttc caaaacaagc tgttgttcaa cctgaaatag
     1861 ataatataag aaaattaggt gtaaaaatag agactaatgt aattgttggt aaaacaatta
     1921 cagtagatga acttatagaa gatgaaggat ttgaagctat attcataggt tcaggagctg
     1981 gtcttccaat gtttatgaat ataccaggag aaaatgcaaa tggagtattt tctgcaaatg
     2041 agtttttaac tagagtaaac ttaatgaagg cttatagaga tgactatgat acacctatta
     2101 gttctggtaa aaaagttgct gtagtaggtg gtggaaatgt tgctatggac gctgctagaa
     2161 ctgcactaag attgggttca gaatcatata tagtttatag aagaagtgaa aaagagctcc
     2221 cagcaagagc tgaagaagtt catcatgcaa aagaagaagg tattatattt aatacactaa
     2281 caaatcctaa ggaaatttta gtggatgaaa atggatatgt taaaggtatg gtttgtataa
     2341 gaatggaatt aggagagcca gatgattctg gaagaagaag acctatagaa atagaaggtt
     2401 ctgaatttgt acttgatgta gatacagtta taatgtcact tggaacaagt ccaaatccac
     2461 taatatcttc tacaacaaag agtcttgata taaataagaa gagatgttta ataacagatg
     2521 aaaacggtca aacttctaaa gaaggtgtgt ttgcaggtgg agatgctgtt actggagcag
     2581 caacagtaat atctgcaatg ggtgctggta aaacagcagc agcatcaata gatgaatatt
     2641 taaaagcaaa agttaatgct taatttgtaa attaaagaga gggtgtctca aaatgaactt
     2701 tgtagtccat gaggcactct ttttgtacaa aatcaaatat attttaatca tttcaacgat
     2761 gaaaatttca ttcctgtata aagtctaacc tttaggtctt agcacaatct ctattttgat
     2821 gtatccactt tttcagattg tttaataatt tataagttat tattgtaata tttaatacta
     2881 agtaacataa ctctgtataa ctatgataaa atagttatac aataaaggtc tataaggagt
     2941 gaataatgtg tggctaataa aatcagattt gtcaaatcta gcattagata atagaaaaat
     3001 aaattgtata attaatggta ttttaatatg aaaaaaagag aaaaagtatt tgatggatta
     3061 gtttttaagc atatattaat tttactaata ttattagttt tgattgattt aacaagcacc
     3121 atcatatatg caagtaattc tatggaaatt acttctagaa atatgataga gacatcaaaa
     3181 agagaacttg aaaactattt agaaataaac atatctttat taaaagctct tagtaaagat
     3241 gatagatttt ctgatagtga aacatctcta attgaaaagg gaaaattatt aagaccatat
     3301 caaaaagaat ataatctttt tatgattggt ataacagata caaaaggaaa tacttcaagt
     3361 acatataggg aaaaggttgg ctcaattaag gataggccta gttttgaaaa agcaattaaa
     3421 acaaagcaag tagtagtctc agatattgaa gttagcaatg tgacaggtga taaggtattt
     3481 attatatatg taccaattat aaaaaataat gagatgattg gaactatttt tgcttctttt
     3541 tattttcaag acgtaaataa tttaataagt agaagcaatc ttgatgattc tattaaattt
     3601 ctaatgatag ataaaaatta tactattatt tctcatccaa acaaaaaata tgtaaatgat
     3661 aaaagtaaga ttcttgattt agaaggaaat attataggga ctactaaaag tgaaatttta
     3721 aaaaatataa atgagaagtg tcaaggtaaa tttttatatt gggataattg gagattatat
     3781 aatgtaaaat atacgaacat aaagtggacc aattggactt tagtatcaaa atgtaatata
     3841 tttaagaact ttcaaagtct aatagttaat tttatgataa agttgtattt ttatatagta
     3901 atatttatga tattgtggaa attaagtaac gctaagttaa tagaacaact taaaaaattg
     3961 gcttattatg attctttaag tggaataaaa aataaagaaa agtttagaaa agattctatg
     4021 tatattttaa agaattatta tcaggataat ttttacttag tacaattaga tgtcaataaa
     4081 tttaaataca taaatgaaat gtttggctat gctgaaggaa ataagatatt aatacatatc
     4141 tcacaggttt taaataataa tacaaataaa tatgaaattt gtgctaggat ggataatgac
     4201 cattttatat tgttgattgc ttgtagcact gaagatgaac ttttaaatag attatctaaa
     4261 ataaataaag aaatttgtaa tttaagtact actaactcat ctaagtataa aattgttatg
     4321 tcaagtggaa tatataagat taataaaaag gatgatatta aaaagattga cctgttaatt
     4381 gatagagcaa atattgcagc caaaagcaaa aaggaaaaat atgaacactc atattcattt
     4441 tttaatgaag aaacaagaaa tcgattgtat aaggaaaaac gattggaaga taatatgaat
     4501 aaagctttag aaaaaggtga atttatagtg tattaccaac ctaagtatag tttaaatgat
     4561 gtaaatgaaa ttgaaggagc agaagctttg ataagatgga atagtccaga atttgggttt
     4621 atttcaccta tagattttgt acctttattt gaaaagaatg gttttattgt aaatattgat
     4681 atgttcgtgt ttgaagaagt atgcaaaaca ttaaataagt ggataaataa aggttatact
     4741 cctgtaccaa tttctgtaaa tatgtctaga gttcatttat atagggacaa ttttatagaa
     4801 aatataactg atttgataag taaatacaat atatctcctg agtttattga acttgaacta
     4861 acagaaagcg ttgtgtttga taatttaaat atattgattg atataatgaa aaagattaaa
     4921 gaaataggat ttcttatatc aatggatgat tttggttcag gatattcatc tttaaatctg
     4981 ttaaaagacc tttcttttga cattttaaaa ttggatagag gatttttaat cgaaacaaca
     5041 gatacaaaac gtggaaaaat tattatttct aagattgtgg agatggcaaa agcgattgat
     5101 attaaagtaa tctgtgaagg tgtagaaact tatgaacaag tagagttctt aagagagata
     5161 ggttgtgata aggttcaagg atacttattt gctaagccta tggtattaga tgaatttgaa
     5221 aaacacttaa actttaaatt tgattaatca taatcattaa taattattat actattagat
     5281 actctaacaa cttacttaca aatatgtaag ttaattgtta gggtattttt atggttaaaa
     5341 tagtatattc acgatattat ggtattgtag taaaaataaa aagttatgga gaatataaaa
     5401 tgaacatatt gagtattaga aatatatcaa aaacatattg tggaaatatt ccatttaaag
     5461 cattagataa ggttagttta aatatagata aaggagaatt tgtgtctgtt atgggaccat
     5521 ctggaagtgg caaatctact cttttaaata taatatctac agttgataga cagagtgaag
     5581 gtgaggttat attagatgga tatgatataa gtaaattaga aggagaaaaa cttgctgaat
     5641 ttagaaggaa acaacttggt tttgtatttc aggatttcaa tttgattgat actttaactg
     5701 ttggcgaaaa tattatgttg ccacttacac tagaaggggc aagtattaaa gatattaata
     5761 tacaaactag aaatatctct aaatttttag gaatagataa aattttagat agaaaaacct
     5821 atgaaatttc aggagggcaa gctcaaaggt gtgctattgc tagagccatt ataaataaac
     5881 ctgccatact tcttgcagat gaaccaactg gaaatcttga ctcaaaatct actgatgatg
     5941 ttctgaaatt atttactaag ataaacatag aacaaaatgt aacaacactt atggtaactc
     6001 atgaagcata tagtgcaagt tattcagata gagtgatttt tataaaagat ggttgtatat
     6061 atacagaaat aaaaaaatct gaaagcagta attctttcta ttctgatata ctagctgtat
     6121 tgtctcaaat aggaggtgta agatagtgga ttttaaaaaa tttgcttata ataatatagt
     6181 tagaaatttt agagcatatt tagcatattt tttaagttcg gttttttcta taatgatatt
     6241 ttttgtcttt gcagtatcta tgtttcatcc aattataatg aaatctggaa tccaaagtgg
     6301 ctttactgca tttatggctc ttatgacttc agaattaata atcttaggtt ttagtctact
     6361 ttttatattg tattctttag gaaacttttt aaaatataga ttgaaagatt ttggagtatt
     6421 gatgataatt ggaatgagta acagacaact gaaaaaattg atattaattg aaaatttgat
     6481 aatagggttt ttagcagtga tgttaggaat attacttggt ttatcaattt ccaaattgtt
     6541 tttattgtat ttaagcaaac tgttttatat gaatttaact gaactttatt ttccggtaaa
     6601 agcaatacta ttgactgttg tatcatttat gattttgttt ttaataacag gaccaatgag
     6661 cttaaaatta ttaaataaaa agagtatttt agagctttta ctaggtacaa aaaagcctaa
     6721 aaaagagata aaatcttcaa agttatttgg aatagctggt atagtatgtc ttatattagg
     6781 atatgctatg atactatttg gcaataagtt aaaaataaat ggaggtatgt atacaacaac
     6841 actgttaatt actttgggga tatttttatt tttttctcaa tttacgattt tgatattaaa
     6901 gtatttaaaa aataaggaaa aattttataa gaacaaagta aatatgttac ttataagtaa
     6961 tttgatgtat aaattaaagg ataatacacg attgttattt ttaataacaa ttcttttatc
     7021 agccacttta gtagcattta caacaacttc aacacttgta agttctcaag gagaatcttc
     7081 taaaaataat tttccaatgg tttactcata tttttcagag cataataatg aaaaagaata
     7141 tgaagaacta caaaaaatca gagatacaat caaaagatat gattataagg agttaagttt
     7201 tcctatactt caatataata gggaagtctt actaaatgta aaggattata acaaactatc
     7261 aaaggaattg ggattagata aaattagttc aaagttaaga aagtatgaag gtattataat
     7321 tcctagtagc aattcacaag aacatataaa ctctttaaaa gaattaagaa attatagtat
     7381 aaaaaattta aatataaaaa taaaaaaatc aacaaataaa ataatttttc ctacaggatt
     7441 gttcagtaaa gtagtagtta taagtgacga tttatacaat gaagtaaagg gtgaattttc
     7501 aaaaatgaat tttcatggat tcgattataa aaactggcaa aacagtgcaa agataactga
     7561 aaatttaaaa gtaaaacatt ttaatttgga tagagaatat aacaggtcat attttttaac
     7621 attaccagat atgtatttag tagagttaca acaaagtaaa attcttcaat ttatgggtgt
     7681 ttttatagga gtcatattat ttatagcagt ttttagtttt ttatatttca gattatatac
     7741 agatgagatg gaagataatg taaaatataa aaaactatca aaaataggtc tatcttttaa
     7801 aaatatgaat aagattgtta gtatagagat aggaacatta ttttttatac cgtattttat
     7861 agcaattata aatagcataa tttctttatt gtttttaaat caagtattaa ataatagttt
     7921 taacttagaa aatctgggta tattactact aatatcatct atatattcac tttattttta
     7981 tctattaaaa aaattttata ctagaaaagt ttggtttttt gattaaagtg gtatataata
     8041 gatatataaa ttaatattta aaaagtagtt aatattaggg gagggcattt gcacctccct
     8101 tgtaatatgt ggaaaattga atattagaag aaggaggaga cttgatggaa aatcaacaat
     8161 tattaggaac agaacgaatt agtaaattac tactaaaata ttctatacca gctataatag
     8221 gtatgttggt aaatagttta tataatgtag tagatagaat ttttattgga aatataccag
     8281 gagttggacc acttgcaata acaggtcttg gtgtgacaat gccaataatg acaataatac
     8341 ttgcatttgg aatgttgata ggtataggta ctactactac catatcaata aaacttgggc
     8401 aaggtaaagt agaagaggca agaaaactta taggaaatgc aatgacgtta tctgtaataa
     8461 caggaattat cataatgata cttggaatat tatttgcaaa taaaatactt acattgtttg
     8521 gagcaagtga aaatacctta atatatgcaa aatcatatat aaatattata ttattaggta
     8581 cagtagtaaa tcttctttcc ttttctttaa accactcaat aagagctgat ggtagtccta
     8641 aaatttcagc aggaataatg atagtaggat gtttaactaa tatagtttta gactggatat
     8701 taatatttgg attcaatttg ggaatacaag gcgctgcaat tgctacagta acttctcaag
     8761 ctcttacagc tgttttaact atagggtatt atataagtgg aaaatcaaac ttacgattca
     8821 gtaaatctaa tctaaaatta gatacaaagc taataaaagc agtgtttgca ataggaatgt
     8881 cgccatttgc gatgcaactt gcagcaagtt tagttcaagt aatatcaaat attgcactaa
     8941 aaactcatgg tggagattta gctatagggg ctatggctac tatttcttct attgcaatgg
     9001 tatttttgat gcctatcttt ggaataaatc aaggagcgca acctattata ggtttcaatt
     9061 atggagctga aaaatatgat agggttaaaa aagcatattt aggttcatta gcagtagcta
     9121 ctataatttt atgtatgggt atggtagtaa ttatgctttt cccagaagct attataggta
     9181 tatttaataa agaccctgaa cttatgaata tatctgttaa tggattaaga atatacttac
     9241 ttatgttgcc aattgtaggc ttatcagtta caggaacaaa ttttatacaa tctataggaa
     9301 aagcaaaaat ggctatgtta ttgagccttt taagacaagt aattttattg ataccagcag
     9361 tattaattct tcctacattc ttaggtttac agggtgtatg gacagctcaa ccagtgtctg
     9421 attttatagc tacagtaatt acaggtatag ttgtatttag agaattaaaa agatatactc
     9481 ctaaaactga aaaattaaat gaaaatgaaa gattaaatga gataactact gagtaaaaat
     9541 ataaattcag ataattgagc aagaaattgc aaaaaataca attatatgat aaaataaaac
     9601 cgctgtcaag gataagagaa attctaatta tggagtgatt ttatggaatt tacaaagaaa
     9661 agcaaattaa aaaatatgta tgtaaacatg aatgtagcta gaatgttgtc taagataaat
     9721 gagtataagg gtagacaact gctttacaaa aaacaaccaa aagaaatttt agaaaactta
     9781 gaaaaaaaat ctttagtaga ttgttctgaa tctacataca ttggaaatca aagagatagt
     9841 agtaatttta atctagaaaa attgataagt aatgaagtta cacctagaag tagagaggaa
     9901 ttgagtattg ttgaatacag agatgtagta aaaactatta acagtgctta tgagagtatt
     9961 ccaatcagtt cacaaacaat tcttgagctt catggatact tatataaatt ttcatctact
    10021 agaggaggaa gttataaatc agataatgat tttattgaac acaatttaaa acctagcgaa
    10081 tttataagta ttgattcaag tgtaaataaa gttgaaaaag ctgtagaaga aatatgtgaa
    10141 gcttataata cattgataga ggaagatgaa attgatatat taatattaat ttctgcattt
    10201 gtgctagatt tcatattgat acatccattt aaagaaggta atataaaaat ggcgagagta
    10261 cttatcctat tgttactaaa taaaaatgga tatgaagttg gaagatatat aagtttagga
    10321 aagatatttg atgatagttc atatgaatat tatagtaatt taaattattt gaaagcgtct
    10381 ataggtagtg aaaaagcaga tatgaatgca tggattgagt attttttaga gactatattg
    10441 actgcatatg agaagctaga tgagagttta aatatatctg ataagaaaag acagacaaaa
    10501 actagtagaa tagagaaaat aataaattct acccttggat attttacaaa agaagatata
    10561 agagatttat gtcctgatat tccagaacct actataaata gagtttttaa caatctaaga
    10621 aaacaagata agatagaagt tgttgcaagg ggaagaagtg caaaatggaa gaaaaaatat
    10681 taaaaaatat ttaaataact aaaatggtat agtgttttgc actataccat ttttagtatc
    10741 actagcatgg gcaataattt aatagcttaa gcaatatcaa ttttatttat tgattatttt
    10801 tgaactgaaa aaagggatta tatggatacc tcaatggtaa ttaattttgg aggagaagat
    10861 ataacattac agaatatctt aggtgtatat gtagaaaaaa taaaatataa taaacgtgtg
    10921 aggtttagta attaaaaaat tatgtagctt cgcacttttt tataaaataa agatacttag
    10981 cagaataata ttttagttga tatatttata aagaggtgct tgtttgggta aaagtataaa
    11041 taataaaaag tagaagtcat gtatataaaa atataagcta tattctataa taataattat
    11101 tttataattc aacaaaagaa tagaatgggt atatttgtga aataataata taaaataatc
    11161 ttaggagtga gcttatgaag aaaaaattat tatatataaa tgtaaattca aagcctgaag
    11221 atttatcttc aagtaaaact gtagcaagaa aatttataaa taaatttata gaaaaaaaca
    11281 aagattttga ggttgaagag atagaccttt ataaagaaca tataccaaga cttgagtatc
    11341 agtactttga aaagagaaat agcattgtta gcgaagaaaa tgctaaaaat ctagacgaca
    11401 aagatagaaa agaacttaca aagattagaa atctttgtga ccaatttgtg agtgcaagtg
    11461 tatatgtaat agcagcacct atgtggagtt tgtcttttcc agcaccactt aaagaatata
    11521 tagattgtat aattcaagat ggaaaaacta tatcttttga aggaaatgat aaaccacaag
    11581 gaattttaaa tgatattgat agaagtatgg tatatataca atcctctggt ggacacatac
    11641 catgggtatt gaagccagtt atgaataaag ggttaaatta tgtggaaagt attatgaaat
    11701 ttataggaat taaaaagttt gatgaattgt tagtagatgg aactggaact agtgaagaag
    11761 aaagacaagc tgcaatagaa aaagcatctg aaaaaataga tggtataata gatggtatga
    11821 agttttagat ataatatttt attaaaaata taaaggaaaa acctctttta atgtagaaac
    11881 ttatattgaa ggaggcgaga atcatgcgag aagaaaaaag taatgaaaag tatgattgtt
    11941 attggtgtaa tcaagagaat aatttctgtg tagaaataaa agataatgta gttatgatag
    12001 atgatggcac tggtacatta aaacaagcca ttttcatagg gtataaacaa atccaaatta
    12061 atttaaattg ttcacattgt caaaacttaa atagaataaa attaaatttg tagaatttta
    12121 aaatggaact tattgaagga attaaaaata gaaagtgtta atatttagac tgaaaattat
    12181 attttataca ataagagttt atttaaataa cattgtatct taatatttat tttcagtctt
    12241 actttattaa aattattttt tagctatatc tggaaaatat ctatctacta atttttctga
    12301 aatgtttttt aattggtcag ccattgaagt taaacttaat aaggctatca ataaatcatc
    12361 tttattttct ggatttatac tgatattttc aaaattagac tctataaagt ctggcatatt
    12421 ctttctttga ttttctttta tcaacatgaa tttttcgtaa catgaaacta aatctttctc
    12481 actgaaatta tccttttcat acacaccatg taagattctt ttaatttctt gtattgtaag
    12541 tgtatttttc atagaataaa taattatcat ctgtaaaatt tgttctttag tatacttttt
    12601 tcccttaact ggtttgatta atccctcttt gctgtaatta tttatcatgg ttttagtaag
    12661 aattttatca ctttcaaatc ttttattagc agaaagctta ttgtcaatta gagaaataat
    12721 ttgatccata tacaagtcaa tagagggaat atcgtttgaa gttatatctg cattatttag
    12781 tgtttctagt attatagtac taagttcatt attcatcata tgttacctcc ataatatata
    12841 taatacacta aattagaaaa taaaacaata ttaagacttg taaaaaaaac ataaagtggt
    12901 ataattaaat atataatata gtaatgaaaa ctatattaat gagtgtgatt tttaaataca
    12961 taattgtagg aggatgaaat gtatcaattt tttttaaagg gtagagaccc aataagcagt
    13021 ttaactcatt ttataggtgc ttgtttatct cttttagcaa ctataatttt agtttttcaa
    13081 tctgtttcat tacatgaaac ttctctcttg atgataatat ctgtatcagt atttggactt
    13141 tcactaattg ctttatacag tgcaagttcg tattatcatt ttttaaaggg tacaccagaa
    13201 caagaattgt tttttagaaa agtagaccat gcaatgattt atgtattgat tgctggttct
    13261 tatacaccaa tatgtctaaa ttttatggaa aaaaaagaag gcataatatt tgttacagca
    13321 atatggatag ttgcattcat tggcataata ataaaaatat tttggatgga tgcacctagg
    13381 tggttatcta cgagtatata tttacttatg ggttgggcaa ttgtttttga tataaatgcg
    13441 ttcaattcaa ttcctaagga ttgccttaga ctattaatta tggaaggtgt atcttattct
    13501 ataggtgcaa ttatttatat aattaaaaag cctaatataa gtcctgaatt tggatttcat
    13561 gaaatatttc atatttttat tatgataggt tctttatttc actttttagc agttttattg
    13621 tatgttttat agttttaaaa gattcgatta attgatacta aaattctaca atgaataaaa
    13681 tggaactgcc ttatatagat tatatcttcg acaataagac agttccttat tataaatatt
    13741 aaattctact tataataaaa ttttgataaa aatagtccat tcaaaatgcc tattccataa
    13801 ttcctttaat gtacttttca tttacgacat atagtttgaa tttatgtact ataattatat
    13861 cctctaaatt ctctgaaaca ctaacaattc tgacacattt gtttctaatt tctacaggca
    13921 aatctaaatc atttgttaaa ttcacatagt catcatattt atacataaaa tcatcccttt
    13981 acattaagat atacttatta tactatattt taataagttt ttttaaatta ttacaatttt
    14041 tcccgaaatt tcatttttta tacataaaat ttccaaatta ggtgaagatt aaatttttta
    14101 ttgtataatc aaaagttaca tataaaatat tttattcgat tttttaaata actattgcca
    14161 atttttgaaa aatatattat tattaatagt aacaaaaaac tgtaaattta gaatattaat
    14221 aaaaattatt taggaggaaa ttatcatggt gagattaaat atagtaaaat taaatacaaa
    14281 attaaatcat caccatcatc atagataaaa gggattgtaa tatgaaatta attcatagac
    14341 acaagccctg tttttagtgt aattggtctt gtatctatga tgggaagtaa ttttaagaga
    14401 aaattatagc catataggta taaagcctat atggcttttt attgttttaa atttgcaaat
    14461 ataagagtaa atttaatgaa gagggtgaga atgtgaagtt tttgaggatt gaagatgagg
    14521 ttatttattc taaaaaaaga tataaattaa aaagagaaat agataaactt tttttggatg
    14581 aagaatattt tcaaatagaa ccacaattat ttgaagagta tgatgaattt ataactataa
    14641 ataataaaat tccagaagaa tctatggtaa aggttgtaaa tggaaaagta atggtactta
    14701 gagctgatat aactacaagt ataataaaaa gtcttgtacc tagatgggaa gatggtttaa
    14761 agcttaagct tttttataat tcatcaatat ataaaaataa aaatacagtt ggaataaaag
    14821 agataagaca aataggttgc gagtatttag gagaatcttc tgtagaagca gatagagaag
    14881 tagtgaaatt agctcttaag atacttgaaa aatacaataa taaatttatt ttagaggttg
    14941 ggagtagcaa gtatattcat ggtttgttag aagaattaaa tttaaataag aattgtgaaa
    15001 atcaaattaa aaatttacta tatactaaga acattcacga attaaaagta tatattgaag
    15061 agctaaaaat taagtgtgaa gtaaaagagt tattatcaaa tattttaagt ttacaaggaa
    15121 atttatacaa cgttattgaa aaatcaaaca agttctattg taataataag atgaagcaag
    15181 ctcttgaaga attaaagcaa gtgaataatt taattgagga atgtaatttt ttagataagg
    15241 ccagatttga cttatcaatg attacgatgc ttgactatta tgaaggaatt atgtttagag
    15301 gatactatcc aaattcatat aaagaaattc ttagtggtgg aagatacgat tctttaacta
    15361 aagaatatgg aaaagaaatt ccagccattg gatttacact aagtgttgat gaattaatga
    15421 agtatgtata taagtaaagc tgagaaggag gaattgattt ggattatttg actatagcac
    15481 tagcaaaagg acgaattgaa ggggaatcat ttaaaaaatt aaaaaaaatg ggtttaggaa
    15541 atagtataga cacagataca agaaaactaa tttttaaaga cgaagaaaat aaaatcatat
    15601 atatacatgt aaagccatca gatgtagtta catatgttga aaaaggagtt gctgaccttg
    15661 gtatagcagg taaggatact attttagaga atgagacgga tgtatatgaa atatatgatt
    15721 taggttttgg aaaatgtaaa tttgctgtgg caggattaaa gggagatagc atatatagag
    15781 aagatgaata tctaaaagtg gcaacaaagt atcccaatat agcgaaaaag tattttaaag
    15841 agaaaggtca aaaaatagaa ataataaaat taaatggttc tgtagaacta gctccaatag
    15901 tagggttgtc agatgtaatt gtagatattg ttgagactgg caatacgctt aaagcaaatg
    15961 gtcttgaaat attagaagat atatgtaata taagcgctag aattatatca aatagagcta
    16021 gctatagatt taaatacgaa caaattcaga atataattcg tttgtttgaa gaacttgata
    16081 attaaaatat aatggaactt tacaaggagg ggtttaagtt gagagaaaaa gaaagtataa
    16141 gagagttaag aggatatgaa ccaaatcacg taaactgtaa agtaaaactt gatgcaaatg
    16201 aaggaagtaa gaggttgttt aaatacctta ttaaagagat tgcagatagt aatatagatt
    16261 taaatttata tcctgaagat tcttatagtg atttgaaaga atctataata gattacataa
    16321 atatttctgg agtaagtaag aaaaatcttc tagtaggaaa cggttcaagt gaaataattg
    16381 atttaataat acatactttt gtagataaag atgaagtaat actgagtttc tctccaagtt
    16441 ttagtatgta ttctatatat agtcaaataa atggttctaa atttataggt gttgaaagtg
    16501 atgaaaattt agttatagat atagataatg taattgaaaa agtaaaggaa aataatccta
    16561 aaatagtaat tgtatgcaat cctaataatc caactggaac aatactaaag aggaaagata
    16621 taaaaaagct tttagattca actaatagtc tagtggtttt agatgaagca tatatggatt
    16681 ttggagaaga aagtatgtta agtgatgttt ttaagtacga taatctaata gttcttagaa
    16741 ctttatcaaa ggcgtttgga ttggctggaa taagaacagg atatatgtta tctaatagca
    16801 gtttaataaa ttctgttgaa aaagtaagac ctccatataa tttaaattca ttgtcagact
    16861 ttattgctac aagagcactt agaaataaag atgtggtaaa ggcttatata aaggaagtaa
    16921 aagaggaaag aaaaatttta tatgaagaga tgattggtat gggaattaag gcatataaat
    16981 cacaagcgaa ttttatattg ttttactctg aaatcgaaaa tttatcacaa aaacttattg
    17041 atagaggagt tttaataaga aaatttggtg gaaagttaga aaattattat agggttacga
    17101 ttggtgataa agaagaaaat gctatgttta ttggagctat aagagatatt ttgaaaaagg
    17161 agaaataggt atgagaattt ggaatgtaga aagaaatact cttgaaacac agatttcagt
    17221 agaattaaat attgatggct ctggtaaagc tgaaatagat actggaatag gatttttaga
    17281 ccatatgctt accctaatgg catttcatgg caagttcgat ttaaaagtga tttgtaaggg
    17341 tgatacatgt gtagacgacc atcatagtgt agaagatata ggtatagcca taggtgaatc
    17401 atttaaaaat gctctaggtg ataaaaaagg aataagaaga tattctaata tctatatacc
    17461 tatggatgaa tctctatcaa tggtatcaat agatataagc aacagacctt atcttgtatt
    17521 taatgctaaa tttgatatac aaatgattgg tagtatgagc actcaatgct ttaaagaatt
    17581 ttttagagct tttgtaaatg aatctagagt aacattgcat atcaatctct tatatgggga
    17641 aaatgaccat cataagatag aaagtatttt taaggcattt gcaagagctt taaaagaagg
    17701 tagtgaaata gtttctaatg agatagcatc ttcaaagggg gttttgtaga atgaatataa
    17761 tagtagatta tggtcttgga aatatagatt ctgtgtctag aggtttcaga aaagctggga
    17821 tagaaactaa aatttctagt aatatagatg aaataaaaca ggctgattca cttatacttc
    17881 caggtgttgg agcttttaga gattctataa gtgccttaga aaagctagga ttgataccaa
    17941 taataaaaga gcatgtttct aatgggaaat ttatgatagg tatatgtcta ggaatgcaat
    18001 tactttatga aaaaagttat gagtatggag aatatgaagg gttaggactt ataaaaggaa
    18061 gtattgataa actggatata agtttaaaag taccacatat gggatggaat aatttaaaat
    18121 ttaataaggc aaatgatgat atacttaaat atataaacga agatgattat gtatactttg
    18181 ttcactcata ttatgcaaat tcatcaaatg aagaactagt tgcattttca gaatatgaga
    18241 agaaaattcc tgctattgtt agaaaaggca atgtatatgg tatacagttt caccctgaaa
    18301 aaagtggaga agtaggttta aatatattaa gagcatatgg ggagatgata aaatgataat
    18361 atttccagca atcgatataa aagataataa gtgtgtgaga ctcacacaag gagaatttga
    18421 caaaataaat gtatattatg ataatccgtt agaagtagca tataaatgga aaaatgaagg
    18481 agcagaatat atacatatag tagatttaaa tggtgctaga agtgaatttg gtgtaaatac
    18541 aaaaataatt gatgaaatag caaacaatat agatatacct attcaagttg gtggtggagt
    18601 tagagataag gaaaaagtta aaagtttaat aaatgctggt gttactagag taatattagg
    18661 tagtatagcg gttgaaaatt tgaatttggt tgaagaattg gtcaatgagt ataaagagaa
    18721 aatagtggtt tctatagatg ctaaagatgg aaaggtagca gttagagggt gggaaattgt
    18781 aagcgatgta gactcattaa cattgtgtaa acaacttgaa aagataggtg tacaaactat
    18841 tgtttataca gatatatcaa aagatggtat gttgcaagga ccaaatttta atatatatga
    18901 aaaaatagca aaggaaacat cattaaatgt tattgcttct ggaggcgtaa cttctataga
    18961 agacgtaaaa agactaaaag ctatgaattt atatggtgca ataataggta aagcgcttta
    19021 tgataaaaag atagacttta aggaggcaca acaattatgc ttactaggag aataatacct
    19081 tgtctagatg tgagaaatgg aagagttgta aaaggaaaaa aatttaaaga tatagtagat
    19141 gttgatagtc cagaggtgct tggaaaattt tatagtgatt gtggtgcaga tgaactcgta
    19201 ttctatgata taactgcatc aaatgaagag agaactacgt ctttagaatt tgtgacaaaa
    19261 gttgcagaaa atataagtat accattttgt gttggtggag gagtaaataa attagaagat
    19321 ttcactgata ttttaagaaa aggtgctgat aaagtttcta taaattcatc agcagtcaaa
    19381 aatcctgaat taataaggga agcttcatta aaatttggag cacaatgtgt tgttttatcg
    19441 atagatgcaa agaaaaatga agagggttca tggagcgtat atgtaaaagg tggaagagaa
    19501 aaaactaatc tggatgcaat tgaatgggct gttaaaggtg tagaacttgg agcaggagaa
    19561 atcgttgtaa atagtatgga cgaagatgga atgaaaaatg gatatgatat tgaattatta
    19621 tcaaagataa cttctttagt aaatgtacct gttatagcat ctggaggtgc tggaaaaatg
    19681 gaagatttct atcaggcggt taataaatct aatgtagatg gaattttagc agcatctgtt
    19741 tttcattttg gtgagataaa aataaatgat ttgaagaaat atttaaaaaa catgggtgta
    19801 gaagtaagat tataagttaa atattgaaag gagattagaa atatgaataa taaatgtaac
    19861 gatatataca ctgatgaagt agatgaattt ataagaagta taaagtttga tgataaagga
    19921 ttagttcctg ttgttgttca agaggtagtg agtaaagatg tactgatgtt agcatatatg
    19981 aataaagagg ctataaagaa aacattaaaa gataaagtgg cttgctattt tagtagaagt
    20041 agacaagaac tttgggttaa aggtgagaca tctggtaata ctcaaaaagt agttaagatg
    20101 tcttatgatt gtgatgtaga tacgatacta ctttttgttg aacaaactgg tgtagcttgt
    20161 catacaggaa attattcttg tttttacaga gacttgtttg atgatactgc taaaatggaa
    20221 cttgaagtac aaacaaatat attgaaagaa ttatatgatt taattaatga aagaaaaaat
    20281 aatccagttg aaggttctta tactaattat ctttttgaaa aaggaataga taagattctt
    20341 aaaaaagtag gtgaagagag tagtgaagta attatagcgt caaaaaatac cgataaaagt
    20401 gaacttattt acgagattag tgatttagta tatcatacat tggttttaat gatagaaaaa
    20461 ggtgttgaaa ttgatgaaat aaaaaaagaa ttacttaaaa gaagaaaata ggatagaata
    20521 gattaatgct aataagaaaa tataccgctt ttaataaaaa gtggtatatt tttttatttt
    20581 atattttcga tttatagaat aatatttgaa ttacttgata aaattaacta tatatataat
    20641 ttgttgataa aataattgta gtacattatt tattttagaa aaaaggtaat tatctaatta
    20701 tatttaagaa taataatatg aaaataattt ttatattaaa aaatatgaat
//
LOCUS       DBGJFK010000073        20632 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.073, whole genome shotgun sequence.
ACCESSION   DBGJFK010000073 DBGJFK010000000
VERSION     DBGJFK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.073"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..694
                     /locus_tag="ACOIAP_002916"
     CDS             <1..694
                     /locus_tag="ACOIAP_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2639794.1"
                     /translation="GYSDVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYD
                     LSTVELISHPNCFIPKKHGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIP
                     SINNFEKRAKIGKCKIGDLWEDDYVLDDSAIICKTGKGIFIVTGCSHSGICNIVEYAK
                     KVCGDDRVIGILGGFHLFELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILN
                     VNEVGVGLTISI"
     gene            1295..2485
                     /locus_tag="ACOIAP_002917"
     CDS             1295..2485
                     /locus_tag="ACOIAP_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639795.1"
                     /translation="MQKNVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNDCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGIVLLAFTIFGAMLVSKAATAMTIA
                     ILLCTLTIFIVGIKAKAPEITEILSNRTSFTPGYFKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMILSFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     IENL"
     gene            2661..3050
                     /locus_tag="ACOIAP_002918"
     CDS             2661..3050
                     /locus_tag="ACOIAP_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5071 domain-containing protein"
                     /protein_id="HGZ2639796.1"
                     /translation="MENIEELLPKDKFDNSNIEKLKLLSDEEIRPICYRLLEWMQDYN
                     WPVAKEILPVLALHQELITPLIIDVLTEEDDDWKYWIISCLLPLFADKNLEPIVPFVK
                     RIAENPTKWECEAEVDEIAKVFLKRIL"
     gene            complement(3273..4400)
                     /locus_tag="ACOIAP_002919"
     CDS             complement(3273..4400)
                     /locus_tag="ACOIAP_002919"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGZ2639797.1"
                     /translation="MKGKITMDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEG
                     KDVIAEAQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESK
                     DVSILAAYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQ
                     MLLMGFKNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLN
                     NIKQEVVETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLH
                     SDIAQSKRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIG
                     RTGRAGEEGYTCAFIDPKNERMLSEIETAIESKINRRIIEL"
     gene            4845..6038
                     /gene="nifV"
                     /locus_tag="ACOIAP_002920"
     CDS             4845..6038
                     /gene="nifV"
                     /locus_tag="ACOIAP_002920"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004410 - homocitrate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HGZ2639798.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            6063..7988
                     /locus_tag="ACOIAP_002921"
     CDS             6063..7988
                     /locus_tag="ACOIAP_002921"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HGZ2639799.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIDGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKENNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLSNGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            8010..9005
                     /locus_tag="ACOIAP_002922"
     CDS             8010..9005
                     /locus_tag="ACOIAP_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HGZ2639800.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHDVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIL"
     gene            9334..9807
                     /locus_tag="ACOIAP_002923"
     CDS             9334..9807
                     /locus_tag="ACOIAP_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGZ2639801.1"
                     /translation="MLGSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNILKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTNKSLEVYELIIEEENRSIEICFKNFTDEEKQVVTKLLEKMSKNAENEWFKVKR"
     gene            9841..10335
                     /locus_tag="ACOIAP_002924"
     CDS             9841..10335
                     /locus_tag="ACOIAP_002924"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2639802.1"
                     /translation="MIRKANMNDLESIMKIIKSTVKEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKKGI
                     ASKLVDFAEKLARENNVLYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            10414..10953
                     /locus_tag="ACOIAP_002925"
     CDS             10414..10953
                     /locus_tag="ACOIAP_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2639803.1"
                     /translation="MKGMIYVIEFLKKRRSIRKYKDIEVEKEKLDKILKAALLAPSSK
                     GLRTWEFIVVDDKEKLIKLSQCRTKGGGFFLKNAPLAIAIIADKEKNDVWIEDASIAA
                     SYIQLQAHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPDKYSVECIISIGYPDEE
                     KKAYSDSDLDYEKVHFNNF"
     gene            11142..11453
                     /locus_tag="ACOIAP_002926"
     CDS             11142..11453
                     /locus_tag="ACOIAP_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639804.1"
                     /translation="MGIFKTKIDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKNLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            11481..12167
                     /locus_tag="ACOIAP_002927"
     CDS             11481..12167
                     /locus_tag="ACOIAP_002927"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGZ2639805.1"
                     /translation="MKYSYKKCIIDSILLMLIVQLLRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNSILIEKCKLILFVVVLSLA
                     IISTYCTKGYVFFNVTMMTLSVFIVPIFEELFFREYIWNYLSNFIKSKIKIICITSIL
                     SGIYNIGYIDIIRNYIALYNNSSYTFEVIISKIIIGTVFGIVLGLVRYRFRDVRLCIL
                     LRSLFAIFIR"
     gene            12399..13283
                     /locus_tag="ACOIAP_002928"
     CDS             12399..13283
                     /locus_tag="ACOIAP_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HGZ2639806.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YDYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEQPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DVVECKVEGIGVLKNIVD"
     gene            13382..14557
                     /locus_tag="ACOIAP_002929"
     CDS             13382..14557
                     /locus_tag="ACOIAP_002929"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HGZ2639807.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGIPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDNAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            14685..15539
                     /locus_tag="ACOIAP_002930"
     CDS             14685..15539
                     /locus_tag="ACOIAP_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639808.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWILDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINAGIIEVKKEYELRLNGIKVEKLDL
                     PSSSIAVVKFHENKVEYFLLGDCTLFIKNGESKVIKDRSICKFDNIVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKDGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKIPRFKVKDDSSC
                     LYLDIYND"
     gene            15582..16817
                     /locus_tag="ACOIAP_002931"
     CDS             15582..16817
                     /locus_tag="ACOIAP_002931"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGZ2639809.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSDVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINKLKYQFKINI
                     DRAMNDFKPELIICHHLYLLTAFVRETVKDIKVMSICHGTCLRQLNTIDLEKEYIISN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSRDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELHDFENNLHNAIDSKIQSLLHNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            16919..17860
                     /locus_tag="ACOIAP_002932"
     CDS             16919..17860
                     /locus_tag="ACOIAP_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HGZ2639810.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIKGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEEMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLING
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNIIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVA
                     LVSNKSDKSILSGASKVTAIGISDNSIIEQCLDAVKK"
     gene            complement(18077..18430)
                     /locus_tag="ACOIAP_002933"
     CDS             complement(18077..18430)
                     /locus_tag="ACOIAP_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGZ2639811.1"
                     /translation="MDRKRELKQLYKERKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SIKFQLGAGSCMIKELNNEWKKYGENAFTFEVLELIKHDDNKTKKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            18726..19637
                     /locus_tag="ACOIAP_002934"
     CDS             18726..19637
                     /locus_tag="ACOIAP_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HGZ2639812.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYRITEEDELYIVPTEDAVFSMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLDFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSADEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLIFSKFYTEQLDWIVSFAKDMYKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            19897..20331
                     /locus_tag="ACOIAP_002935"
     CDS             19897..20331
                     /locus_tag="ACOIAP_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6323 family protein"
                     /protein_id="HGZ2639813.1"
                     /translation="MISPIILSSINRNLKEIERNKLFETNIESRDYGLTLSESDVKDI
                     INFRDNTLKGYGRIELDIKVTKQLIENIYISQYTNMDNYLETINDMQEIFYYLKNETD
                     DKICDDEIIEILDELYEKFSGNINNVRGEADEFVKKFKFGEV"
     gene            20354..20602
                     /locus_tag="ACOIAP_002936"
     CDS             20354..20602
                     /locus_tag="ACOIAP_002936"
                     /inference="COORDINATES: protein motif:HMM:NF040016.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6179 domain-containing protein"
                     /protein_id="HGZ2639814.1"
                     /translation="MSNNLSNININENNLIKNQYSISLIKECFDCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAID"
BASE COUNT         8072 a         2100 c         3640 g         6820 t
ORIGIN      
        1 gggatattca gatgtattca tatcaaacgc tgaaaaatta aatatagatt taggaaattt
       61 aacacatgtt gttttttctc atggtcataa tgaccataca agaggtatac agtttttaga
      121 aaatagatat gatttgtcta cagttgaact tatttcacat cctaactgtt ttatacctaa
      181 aaaacatgga gagaaaagca taggagctcc attttctgct gaggaaatta aaaatatttt
      241 tatgtataat cctaaggata agccatttaa tctaagtaag aattgtgtgt ttttaggtga
      301 aataccttct ataaataatt ttgaaaaaag agctaaaatt ggtaaatgta aaataggaga
      361 tttgtgggaa gatgattatg ttttagatga ctctgctata atttgtaaaa ctggtaaagg
      421 tatttttatt gttacaggat gttctcatag tggaatttgt aatatagtag agtatgctaa
      481 aaaggtatgt ggagatgata gagttattgg tatactgggt ggttttcatc tttttgaatt
      541 gaataatagg ctggatagca caatacaata tttggataaa gaagaaataa gaatgttgta
      601 cccttgtcat tgtgtttctt ttaaggtaaa agctaagatg aatgaaatat tgaatgtaaa
      661 tgaagtaggg gtaggattga ctataagcat atagtatttg aaagtatata agatttaagt
      721 tgaaggttaa aaagatattt tctatagaaa gtatcttttt tattatgttt attttaagag
      781 aaatcaatgt acttttatat gaaatattgt gaaaaaattt atttttaata agaatatatt
      841 ttcatcaata aacaatttta ttatgtatta ataatgttaa aataaatata aataaatcaa
      901 agttatttat attgaagtat attttttcac aaattacatt aatttattct tttaaagttt
      961 gataattcca atgaatatga tataataggg aattttatta tgtataatta ttattctatg
     1021 attatatata aataattata gaataataaa gaaaaaatct gtagaaatta acattaaaaa
     1081 agatatttca taaaattaaa aaacgaagta gatttgaaca ttcttaaaaa ataaaataaa
     1141 tatataaaaa atatttaata tagataggga aaaaagttga aaatataaaa atattgggaa
     1201 aatatagttg aatttaatga acaaaaatgt tattgtttta tcaatgaagt gttaaaataa
     1261 aaacatttaa tatcatttta gggaggatga tttcatgcaa aaaaatgtaa agaaagcaaa
     1321 agtaacgggc tctatgttag ccatttttgg cgttgcaagc gttcttttta gttcacatgc
     1381 aggaggagga tttgctacag ggaatcaaga aactcaatac tatgtgcagt atggatggac
     1441 agcaccactt atggcaattt tagcaatgat tatacttact gctaccatga gagaagttat
     1501 cataatgtat aataataatg attgtaggaa ttataaggat ttattttgtg agctttggag
     1561 accatatcca aaacttgaaa taatatggga gatatattac tatctaatgg ttttaatagc
     1621 tgtaagtgct gttatagcag gtgcagcagc agtatttcaa agtatagggg taaattattt
     1681 tgtagctgta tttattattg gaattgtact tcttgccttt actatatttg gtgctatgct
     1741 tgtatctaaa gcagctacag caatgacgat agctattcta ttatgtactc ttactatttt
     1801 tattgttggt ataaaagcta aagcaccaga aataactgaa atattatcaa atagaacgag
     1861 ttttacacct ggctatttca agccaatact taatactttt atttatgcag gttttcaatc
     1921 agttgttata cctacacttg cgggatgttc aagaccactt cttaagaact caaaagaagc
     1981 tactaaggca atgatacttt catttgttat gaatgcaatt gcattagggc ttgctgtaac
     2041 tatgctaatg ggatggtata gagaaattat tgctgctggt caaacaacac tacctactct
     2101 ttatgttgca ggtcaatctg gaaatcatac tatatacata atttataatg ttgcattatt
     2161 cctttgttta atgtctacag gagtaactac tatatttggt cttgtaaata gatttgaaga
     2221 ccataaagca ctttctttcc tttcttcaag aatgaaaaga agggtattta cagcttgtgc
     2281 aataatggta gtgtcaatgc ttatatcact tacaggatta agtaatattg ttaaatatgg
     2341 atatggatat tgtggttatc ttggtttatt tactatagta attccattcc ttacattagg
     2401 acattataag aacaagaagt ttgcaaagga aaatccagag gctaaatggc cagcggaatt
     2461 aaacgaaaat attgaaaatt tataaagtga gtagtacttt aaataaaaga tataatctaa
     2521 ttaataggtc gaaaatatag tcaaataaaa atagagtata ttactattta gatatgataa
     2581 aatagggttg aaaaataaat tgataaatta aaatttgaaa gatataatga acataatgta
     2641 tttattagga gaattaagtt atggaaaata ttgaagaatt gctccctaaa gacaaatttg
     2701 ataatagtaa tatagaaaaa ttaaaattat tatctgatga agaaataaga ccgatttgct
     2761 atagattatt ggaatggatg caagattata actggcctgt tgcaaaagaa attttacctg
     2821 ttttagctct acatcaagag ttaattactc cattaataat agatgttctt acagaagaag
     2881 atgatgactg gaaatattgg ataatttcat gtcttttgcc actgtttgca gataaaaacc
     2941 ttgaacctat agttccattt gttaaaagaa tcgctgaaaa tccaactaaa tgggaatgtg
     3001 aagcagaagt agatgaaata gcaaaagtat ttttaaagag aatattataa ataatagttg
     3061 aatatattta ttgagattat tttcaaaatt taatattaaa caacttggaa acaggtaata
     3121 taaaactaac aatagataga aaaagctgta atcataaagg ttacagcttt tttatgcaat
     3181 ataaaatagt attataataa agaaaaagtt gatacctgct ttctgtatat tatagtattt
     3241 atatactatt ggcattttaa ttagtccata aattataatt ctataattct tctattaatt
     3301 ttagattcta tagctgtttc tatttcactt aacattcgtt catttttagg gtcaataaaa
     3361 gcacatgtat agccttcttc accagctcta ccagttctac caatacggtg tatgtagtct
     3421 tctggtgttt ctggtaaatc gtaattatat atatgactta ctccagatat atcaagacca
     3481 cgagaagcta catctgtagc tattaagtat tgtatatcta aatttctaaa tgatttcatt
     3541 attctttctc gttttgattg agcaatatca ctatgaagtt tttgacaatt atatcctctt
     3601 atagcaagag cttcttcaag attatcaact cttctcttag tcctacaaaa tattattgcc
     3661 ataaaaggat tatcttcatc tagcacctta cataatgcat ctaatttttt tctatctgta
     3721 gtttctacta cttcttgttt tatattatta agagttattt cttctttttg aatggaaacc
     3781 acaacaggat tttttgtgta cctataagct aattttttta cttgagaatt tatagttgca
     3841 gaaaagcata gtgtttgctt tttgtttgaa gtttctttta aaatggcttc cacttcattt
     3901 ttaaatccca taagcaacat ttggtctgcc tcatctaaaa caaaagtctt taacttacta
     3961 aggtctattg tttttctatt tagatggtct aaaagtctac ctggtgtagc tataatcata
     4021 tgaatatttc cctttagttt ctttatttga gaaccaatat cttttcctcc atatgctgct
     4081 aggatactta catctttaga ctctttaagt ttcatagctt cttctgttat ttgaatagct
     4141 agttctcttg taggagaaag tataagaact tgtatatcat ttatatctaa tgatatattt
     4201 tcaaatatcg gaagtaaaaa agctagcgtt tttcctgttc cagtttgagc ttctgctatt
     4261 acatcttttc cttcttttat tagtttaata ctttcttttt gtataggtgt aggtgttgtt
     4321 attcctgatt tttttagaat atttattgta ttttcactaa tccctaagct tttgaaatcc
     4381 attgttatct tacctttcat gaaaaatttt cttttttatt aatcaattaa taatatcata
     4441 tttataagta tttttagtaa attttttaat tattatttat atggcttaaa aatatataaa
     4501 gatactttaa aatgaaatgt aacttaaatt aaattttagt aggaatttta taggtttatt
     4561 tttaaaggtt ttttgaaaat aaatctattt aaaaattaaa ttaaaatgca agaaaaacat
     4621 aataactttc atttttaaga agttttcaca aaaaagaaaa aatatagtgc aataaatgat
     4681 acaaagtaat ataatagatt acaagatatg aaaaactaaa aaaataaatt gcaaatgaaa
     4741 ttaaaatgaa taaaaaataa aaaaataatc ataagttaga ggtatcaatg gaaaataaga
     4801 cctaatgttt ttaaaattaa aagtatacta aggggggcat taatatgtgc gttatatcaa
     4861 aagatagagc aaaggaaata aaaatagtag atactacttt aagagacgga gagcaaacag
     4921 ctggggttgt atttgcaaat agagaaaaaa taatgattgc tgaaatgtta agtgacctag
     4981 gtgttgacca aattgaagtt ggtataccta ctatgggtgg agatgaaaaa aatgtaataa
     5041 agcacatatg tagtagaaat ttaaaatcag atataatggc ttggaataga gcagtaataa
     5101 aagatgttga agaatctatt tcttgtggtg ttgatgcagt agctatatca atatcagtat
     5161 ctgatattca tatagaaaat aaattgagaa cttctagagg ctgggtttta gaaaatatgg
     5221 ctaaaacagt tgaatttgca aagaaaaatg gactatatgt ttcagtaaat ggagaagatg
     5281 cttcaagagc agatatagac ttcttaactg aatttataaa tgttggaaaa caagcagggg
     5341 cagatagatt tagatattgt gatacagtag gagttatgaa tcctttttct ataaagaatg
     5401 caatagaaac tctttatgaa agaactaatt ttgatataga aatgcataca cataatgact
     5461 ttgggatggc aactgcaaat gcacttgcag gaatagcagc aggagcaaat tacgttggtg
     5521 ttacagtaaa tggattaggt gaaagagcag gaaatgcagc attagaagaa gttttaatgg
     5581 cacttaagtg tgtttataaa tgcgatttaa ataatataga tactagaaaa tttagaggaa
     5641 tatgtgagta tgtagcacag gcatcaggaa gaatccttcc tacatggaaa ccagtagttg
     5701 gggataatat gtttatacat gaatctggta tacatgcaga tggagcttta aaagacccac
     5761 ataactatga accatttgac ccaagtgaag taaatcttga aagaaaaata gtaataggta
     5821 aacattcagg aagagctgca gttgtaaata agttgagtga atatgaaatg tatatttctc
     5881 cagaaaacgc taccaaacta ttaaatgcta taagagctac atctataaga ttaaaaagaa
     5941 gtttaatgga taaagaaatt cttcaattat attgtgatat actagcacat gagaagggta
     6001 caacagaaga agaagcagtt agaggttcat atatttaaga tataattgtt taggaggaaa
     6061 atatgggaga taatatagtt tataaaataa ttaaaaaaca tatagtagat ggagaagctg
     6121 ttgctggaag ttcaattggt ataaaaatag accaaacttt aacacaagat tccactggaa
     6181 caatgacgta tcttcaacta gaagctatgg ggatagacaa agtaaagact aaaagaagtg
     6241 tggcgtttgt agaccataat atgttacaac aaggatttga aaatgcagat gaccataagt
     6301 atatacaaac agtggcagat aaatatggag tttatttctc taagccagga aatggtattt
     6361 gtcatcaagt atttttagaa agattttcaa caccaggaga tacactttta ggttctgata
     6421 gccacacacc tactgctgga ggtgtgggaa tgatggctat tggagctggt gggttagatg
     6481 ttgctttagc tatggcagga ggagcatact atataaaagc accaaaagtc tgtaaggtga
     6541 atctagttgg aaaattaaat aatatggtat catcaaaaga cataatatta gaagtattaa
     6601 gaaaacaaac tgtaaaaggt ggagtaggta aagtttatga atatggcgga gaaggtgtta
     6661 aaagcctatc tgttccacag agagctacaa taacaaatat gggggctgaa cttggagcaa
     6721 ctacttcaat cttcccaagt gatgaaaaaa cactagaatt ttttaagagc caaggaagag
     6781 aagatgcatg gatagagtta aaaccagatg cagatgcagt ttatgatgaa gagattacta
     6841 taaacctgga tgaattaaaa ccgttagctg caaaacctca tagtccagac aatgtagatg
     6901 aagttgaaaa tataggcaaa attaaaatag accaagttgc aataggaagt tgtacaaatt
     6961 cttcttatga agacttaatg aaagtagcac aaatcctaaa aggaaataaa gtacataagg
     7021 atgtgagttt ggtaatagca ccaggttcaa gacaagtgat ggagatgatt gctagaaatg
     7081 gagctttagc agatataata agtgctggag ctagaatact agaaaattct tgtggtccat
     7141 gtatcggtat gggtcaatct ccaggtactg actctgtgtc tttaagaact ttcaatagaa
     7201 atttctatgg tagaagtggt actctatcag cgcaagtata cttagtaagt ccagaagtag
     7261 cagcagtaag tgcaatcaag ggagtgctta cagacccaag agaatttgat attaaattta
     7321 ccaatttaga tgtaaatgaa tttttgatag atgatagcat gataattaaa cctgctgatg
     7381 taggaagtga tgtagaagta gttagaggac ctaatataaa acctttccct cttaatacag
     7441 agctaagtca gtctatagat ggaaaagtta tattaaagac agaagataat ataactactg
     7501 accatataat gccatcaaat gctaagttac ttccttttag aagtaatata ccgtatcttg
     7561 caaactattg tttcaacact gtagatacag aatttcctca gagagcaaaa gagaataatg
     7621 gtggatttat agttggtgga gataattacg gtcaaggttc aagtagagag catgcagctt
     7681 tagcaccatt atatctaggt gttaaaggag taatagttaa gagctttgca agaatccaca
     7741 aggctaactt gataaatagt ggaataattc caatggagtt ttgtgatgag aaagactatg
     7801 aaaatatatc tcttttagac aatttagaga taccaaatat tttagacaat ctaagtaatg
     7861 gaattttaga agttaagaat acaactaaag gaacttcttt taaggttaaa gtagaattat
     7921 cagcaaaaga agttgatgta ttaaaagctg gtggaaaatt aaactatact aaaaatcaag
     7981 ctaattaata tgaaaagagg gaatattgaa tgtataaagt gacacttata ccaggagatg
     8041 gaataggacc agaagttgcg aaagctatga aaaaggtggt agaagctact ggagtagaga
     8101 tagaatggga agaagttaat gcaggagagg cagttattga agagtatggc actccacttc
     8161 ctgaatatat tatagacagt ataaaaaaga ataaaatagc tataaaaggt ccaattacta
     8221 ctcctgtagg taaaggattt agaagtgtaa atgtaacttt aagacaggca ttagatttat
     8281 atgtcaattt aagacctatt aaaagtttta agggtataaa atcaagatat gaagatgttg
     8341 atttagtagt ggtaagagaa aatacagaag atttatatgc tggaatagaa cataaaatag
     8401 gtgattatgc agctgaaagt ataaagataa taacaagaag tgcaagtgaa agaatcgttg
     8461 attttgcgtg taactatgtt aaagataaca agagaaaaaa agttacagct atacataaag
     8521 caaatataat gaaaatgtct gatggattat ttttagatgt gtttagagaa gtagcatcaa
     8581 aacatgatgt agaatatgat gatttgattg tagatgcagc agctatgaac ttagttttaa
     8641 atccagaaaa ttatgatgta atggtaatgc caaatcttta tggagatata ctatcagatt
     8701 taggtgctgg gcttgttgga ggtttaggta taattccaag tgcaaatatt ggtaaagatt
     8761 gtgcgatatt tgaagctgtt catggaagtg ctccacaaat agcaggtcaa aataaagcta
     8821 atccaacagc acttattcag tcatcagtaa tgatgcttag atacttaggc gaatatgaaa
     8881 atgcacaaaa aatagaaaca gctttagaaa aagtatttct tgaaggaagc aaattgactg
     8941 tagatttagg tggctcagct tcgactacag agtttgcaga tgaggtgtgt aagtatattt
     9001 tatagatttt gtttatggaa aaagtagaat atagattaaa agaaaggggc tttctcaaaa
     9061 tagagagaag cctctttctt tgttaaaatg ataaaatgta tttgattcta tgcaaaagag
     9121 agttcctcat aaacgaaaaa gttcattttg ggatgctcac tttaatttta aaattatttg
     9181 attaataggc aaataaaggt taaataaatt tagtgttttt aattgaactt tcaaccaata
     9241 tatggtaaaa tttaaaaaag ttgaactttc aactaaaaac aaatatattg attatgtgaa
     9301 attctatgaa taaggaactc tgtgacttta gtcatgttag gttcagtgga ggtgtgtttg
     9361 attaagacct tagatagtaa tatattaaga gaagtaggta ctttatctag agcagtaaat
     9421 tcaataaatg atattaagta caaggaatta aagttacaaa aaggacaatt tacattcttg
     9481 acaagaattt gtgaaaatcc tggtataaac cttgtggaat tatcaaacat tttaaaggta
     9541 gacaaggcta caacaaccaa agctatacaa aagttaataa aagctggata tgtggataaa
     9601 aagcaggatg agtttgataa aagagggtat aatttaactc caactaataa atctttggaa
     9661 gtttatgagt tgataattga agaagagaat agaagtatag agatatgttt taagaatttt
     9721 acagatgaag aaaaacaagt ggtaactaaa ttattagaaa aaatgagcaa aaatgcagaa
     9781 aatgaatggt ttaaagtaaa gagatagtaa ataaatacat taacctaagg agatagtttt
     9841 atgattagaa aagccaatat gaatgattta gaaagtatta tgaaaattat aaaatcgaca
     9901 gtgaaagaaa tgaagactta taataataca caatgggatg aaaactatcc attagaaaaa
     9961 gactttgttt cagatattaa gaaacaggac ttatatatat atgaagtgga tggagaagta
    10021 gcaggattta tatgtctcaa ttatgaagag ccagaagaat atctaggctt aaattggtca
    10081 tctaataaaa aagcaatggt aatacataga atggctgtaa atccaaattt tagaaagaaa
    10141 ggaatagcat ctaagttagt tgattttgct gaaaaattag ctagagaaaa caatgtatta
    10201 tacttaaaga gcgatacgta ttcaataaat tcaaaaatga atttattact tacaaagtgt
    10261 ggttttataa aaatcggaga aatgagtttt ttaggaaagg agaaatcttt ctactgttat
    10321 gataaaatat tataaaaagc atttataata caaggggtaa ataataaatt tttggtatta
    10381 gtaagggtat aatataacct agtgtatgcc attatgaaag ggatgattta tgtgattgaa
    10441 tttttaaaga agagaagaag tattagaaaa tacaaggata ttgaagtaga aaaagaaaaa
    10501 ttagataaaa tattaaaagc tgctctttta gctccatcat caaaggggct tagaacatgg
    10561 gaatttatag tggtagatga taaagaaaag ttaattaaat tatctcaatg tagaactaaa
    10621 ggtggcggat ttttcttaaa aaatgcacct ttagctattg caattattgc agataaagaa
    10681 aaaaatgatg tttggataga ggatgcaagt atagctgctt catacataca acttcaagct
    10741 catgaactag gattaggttc ttgttggata caagtaagaa atagaatgca tgatgataat
    10801 atagaagctg acaaatatat tagagaagaa ttaaaagtac ctgacaagta tagtgtagaa
    10861 tgtataattt ctataggata tcccgatgaa gaaaagaaag catacagtga ctctgattta
    10921 gactatgaaa aagttcattt taataacttt tagtatataa tatgttgtat taagacatta
    10981 tattttttta tattgttaat atatacttaa aattgtaaaa atatatctga attttactaa
    11041 cttatctatg ggttatgtac aaggatttta aagataaata tagaaattaa tgtttataat
    11101 cgatacataa cttgagtaac aaaatttaag gaggttaaag tatgggtata tttaaaacaa
    11161 aaattgatga ggactggaaa gtaaactaca ttaaagagtt taatgaaatg agagattctt
    11221 atgagagtaa acttcaaaaa aaacagtttg aagtagatag tttgaaatca gaactggata
    11281 gactaagaag ctataaaaat agccttaagc caaaagaaaa acaaattact gatgatgata
    11341 taaataatat aaagaattta agaagagatg gtttaagtta taaagaaatt tcaaatcaaa
    11401 caagttggag caaggcaact gtaagtagag tattaaatgg actttacgat tagcatatac
    11461 atggggtgat ttaaattggg atgaagtata gttacaaaaa atgtataata gattctattt
    11521 tattgatgct tatagttcag ctattaagga tgattttgaa ttatgtactt ctaagtcaat
    11581 ttgaatttac tcttgaaaat tttaatatta taaacttaat ttcttttaca ctagttggat
    11641 tatcattaat tctattttta aaagataatt ctttgtataa caaggtgaga aatagaaaaa
    11701 tcacagaagc ttttgaagaa aataaaaaca gtatacttat tgaaaagtgt aagctgatac
    11761 tttttgttgt ggttttatct ttagcaataa tttcaactta ttgtactaag ggatatgtat
    11821 tttttaatgt aactatgatg actttgtctg tatttatagt tccaatattt gaagagttat
    11881 tttttagaga atacatatgg aattatctaa gtaattttat aaagtcaaag attaaaatta
    11941 tatgtataac atctatatta tctggaattt ataatatagg atatatagat attataagaa
    12001 attatatagc attgtataat aattcaagct acacctttga agttattatt tcaaaaatta
    12061 ttataggtac tgtttttggt attgtacttg gattagttag atataggttt agagatgtaa
    12121 ggctttgtat actattgagg agcttatttg ctatatttat taggtagata atataattag
    12181 tttataaggt tgttttaaat gtaattttaa atcaacctta ttttatttgt gttctataaa
    12241 gtacttatgt agtaataact aatgaattta ataaaaatta tttgaatatt tttaaaatat
    12301 ataaatatgt attgacatat aaatattatc aattacaatt tatataaact agtaaaaatt
    12361 aaataatatt aatcaactta ttgaatggag gaataaaaat gaaatttgtg actttttgta
    12421 gtagcaatga agaaaaaata ggtgtattta attcagaaac aaatagtata tatgaaatta
    12481 atagtttagg attaagtaaa ttatatacag atatgaatga ttttattgaa aacgtatcta
    12541 caggagattt agaaaaaata aaaaacaatt catttgaaaa tgcaaagtgt tataagttag
    12601 aagaagttaa attatgttcc ccaattgtaa gacctaaaaa agatattata tgtttaggtc
    12661 taaactataa agaccatgtc aatgaaatcc cagatggagt tataaaaaac gtagttatgc
    12721 cagattatcc aatttatttt tctaagagag cagataaaat aattggagta gatgataaga
    12781 taagtttaca tggagactta gtagaaaagc tggattatga atcagaactt gcagtaatca
    12841 taggtaaaga aggtataaat atatcaaaag aagatgctta tgactatata tttggatata
    12901 caatagtgaa tgatataagt gaaagagcac tccaagataa acatgttcaa tggtttagag
    12961 gaaaaagctt agacacacat acatctatgg gaccttgcat agtacataaa gaagaatttg
    13021 aacagccttt aaaattagat ataagtagtg tagtaaatgg agaagtaaga caaaattcta
    13081 atacagaata ctttatattt gatataccta ccataataaa tgatttatca agaggaatga
    13141 ctttaaaacc aggagatata atttcaactg gaactccagc aggtgttgct atgggtatga
    13201 atcctcaagt atatttaaag catggtgatg tagttgaatg taaagtcgaa ggaataggtg
    13261 ttttaaaaaa tatagttgat taatggataa atatgccata taattttatt agtacgaata
    13321 atttaattaa tataggatta atcaaactta tgattaattt attatagaga gggatgagta
    13381 tatggcaaga gaactagaat taaagtatgg ctgtaatcca aatcaaaaac catcaaagat
    13441 ttatatgaag aatggagagc ttcctataga agtattaaat ggaaaacctg gatatataaa
    13501 ctttttagat gcatttaata gttggcaact tgtgaaagag ttaaaagaag ctacaggtct
    13561 tccagcagca acttcattta agcatgtaag tccagcagga gccgcagtag gaataccttt
    13621 atcagatact ttaaagcaaa tatattttgt tgatgattta gagctttctc cattagcttg
    13681 tgcttatgca atggcaagag gagcagatag aatgtcttct tatggtgatt ttatagcact
    13741 ttcagatgta tgtgataaag agactgcaac tattatagca agagaggttt ctgatggtat
    13801 aatagctcca ggatatacag atgaagccct tgaaatatta aaaggaaagc gtaaaggtaa
    13861 ctacaatatt gtaaaaatag atgaaaacta tactcctgaa cctattgaaa caaaggatgt
    13921 ttatggaatt acttttgaac aaggcagaaa tgaaatatta ataaatgaag acctattaaa
    13981 agatattcca actgataata aaatttttac agataatgca aaacgtgatt taattatagc
    14041 tcttattaca ttaaaatata cacaatcaaa ttctgtttgt tatgctaaag atggacaagt
    14101 aataggagta ggcgcaggtc aacaatcacg tattcattgt actagacttg caggtaataa
    14161 agcagatact tggtatcttc gtcaacatcc taaagtatta aacttaaaat tcaaaaagga
    14221 tataggtcgt ccagatagag acaacactat tgatgtatat ctttctgatg attatatgga
    14281 tgtgcttgct gatggcatat ggcaaaactt ttttgaagaa aaaccagagc ctctaactgg
    14341 agaaggaaaa agagcatggc ttaaaacttt aacaggagta gcacttggtt cagatgcatt
    14401 tttcccattt ggtgataata tagagcgtgc aaaaaggagt ggggtaagct ttatagcaca
    14461 accaggtggt tctattcgtg atgataatgt tatattaact tgtaataagt ataacatagt
    14521 catggcattt actaaaaata gattattcca tcattaaaat actgaaaata taaagataat
    14581 atagattaag taaaaatcta caacaagttt tgttgtagat ttttttattt gctgtataat
    14641 tttaaataga actttatttt tagatattca atttggaggt tgatatggct ttaaatataa
    14701 gaaactatag cctattatgt aatcaaggga cagctaaatt taatgaagat gtagtcggta
    14761 taaatccatt tggagcatgg attttagatg gtgctacagg acttaatgga aaaaatttag
    14821 tgtcaactga aagcgatgca aggtggtatg ttcagtggtg gaataggtat ttatataaaa
    14881 atataaataa agaagaatca ttaaagagta ttattaatgc tggaataata gaagtaaaaa
    14941 aagagtatga actaagatta aatggtatta aggttgaaaa attagattta ccatctagtt
    15001 ctatagctgt tgtaaaattt catgaaaaca aagtagagta ttttttatta ggagattgta
    15061 ctttgtttat taaaaatgga gagtccaaag ttataaaaga tagaagtatt tgcaaatttg
    15121 ataatattgt atttgatgaa atgagcaaac tttctaactt ggaagagatg gcatttgatg
    15181 agattagaac tagtgttatg gatacaatag taagtaatag gttgaagaaa aatacgaaag
    15241 atggatattg gatattggat tttgatgagg aagctgtgga aaattctata tatggataca
    15301 ttgaaataaa aaaagatttt caattgatgc taacaagtga tggttttaca agtgcatgtg
    15361 atagatataa tctaataaaa gaagaagaat tgatacgtat agcagaaaaa tttggtatag
    15421 ggtatataca caataaagta agagattttg aagataatga ctataaagcg gttaaaatcc
    15481 caaggtttaa agtaaaagat gattcatctt gtttatactt agatatatat aatgattaga
    15541 ctgtgtaaaa ctatttaatt ttagaaggga ggtaagtgaa agtgaaaatt cttcatataa
    15601 taacacaaaa accaaatagt acaggtagtg gtatatattt gtctggtatg ataaaaggat
    15661 tcgaaaagat aggtcataag caagctgtaa ttgcaggtat agatgtaaat gatgatgtaa
    15721 attgttttcc aagtgatgta agtttttatc cagtaaagta taattgtggg gagttaaatt
    15781 ttcctgttgt aggtatgagt gattctatgc catatgaaag tacaagatat aaagatttaa
    15841 atatagacat gataaataaa ttgaagtatc aatttaaaat aaatatagat agggctatga
    15901 atgattttaa accagaactt ataatatgtc atcatttgta cctattaact gcatttgtta
    15961 gagaaacagt aaaagacata aaggtcatgt ctatttgtca tggaacttgt ttaagacagc
    16021 taaataccat tgatttggag aaagaataca taatatcaaa tataagaaaa ttagatttaa
    16081 tatttgctct tcatgaaaat cagaaatatg atattataaa gacttttgga gtaagtgaaa
    16141 gtaaagtagt tgtaattggt agtggttata atgatgatat attttataat aaaaattata
    16201 aaataaagga tgataaaata aaaatagtat ttgcaggtaa gatatgtaaa tcaaagggac
    16261 taattccatt tataaaagct atatctaaat taaaatatag tagagattta atagaagtca
    16321 attttgcagg tactggaagt gatatagaat catataatga gatagttaaa ctcgcaagta
    16381 agtctccatt taaaatgaat ttcctaggaa agttagagca gagagattta gctgagctat
    16441 tcaacaggtc acaaatattt gtgttgccat cattttatga gggattacca gttgtagttt
    16501 tagaagcctt atcttgtgga acagatgtaa tcactactga tattcttggt gttaaagagt
    16561 ggattggtag tgagattaat aattctggaa agatagaata tgtttctcta ccttttatgg
    16621 agaaagaagg tattccaaag gatgaagagt tacatgactt tgaaaataat ttgcataatg
    16681 caatagattc taagatacaa tctttattac ataactcaaa taaaaaaaca tctgtagata
    16741 tgtcaaaaaa aacgtgggat ggcttagcct atagaataaa tgaagttatt ttaatggatg
    16801 agttgtgttt ggtttaaatt tatttagatt ataaaaaagt gtaactattt ttacactttt
    16861 tttaaatgat tttatattat actaatacta aatatatttg tttttaggga ggtaatttat
    16921 gaggattagt aaaaaggtat tggcgttagg tatttcagca ttattgttaa gtgttagttt
    16981 tccaacatca ataaatgcac tagataagat tgaaaatatt aaaggagtag ataaatatga
    17041 gacagctggg cttatttcag ataagcaaga ttttacaaca gcagttctta tcaacgcgga
    17101 ttctacaatg gtagatggta tcgctgccag tggtcttgca ggagtaaata atgcagctat
    17161 tttattaact aataaggatg atataccaga agcaacactt caaagactga atagagttac
    17221 taagatatat gtaataggtg gagaaaattc tataagtaaa gatgtagaag aaatgttact
    17281 tatgagaaga atgcaagtta taagaattga tggtgtagat agagtagata caagttataa
    17341 aattgcaggt gaaatagaaa aaattaaaaa cagcgataag atgtttttga taaatggatt
    17401 taaggatgaa gctgatgcag taagtgttgc atctgttgct tatagagatg gagctcctat
    17461 aatattgaca aaagatatac cttcagcaga agaagataca gacttagacc catggtttgg
    17521 agtttctcct gttccagtat atgctattgg aggagagtct acactaagtg attacatagt
    17581 gagtagatat agagcaacta gaattggtgg tgttgataga tatcaaacta ataaaaatat
    17641 tattgaaaag ttctataatg gagcaaaaga gttctatata acaagtggag acgatttagt
    17701 ttatgctttg gttgcatcac cacttgcaaa aaatgctcct gttgctttag tttcaaataa
    17761 aagtgataag agtatattaa gtggagctag taaagtaaca gcaataggta taagtgataa
    17821 tagtattata gagcagtgtt tggatgctgt aaaaaagtaa tagagtgtca ttagtaaaat
    17881 gaatatatac cattgaaaat tagtagatag ttcattttat aatggtataa aatatatgag
    17941 aagaggctat caaatagaga taagcctctt tttcattgtt aaaattatga aaatatattt
    18001 atttcataaa aaagtatcac atgaactaaa tgtctatttt gagacactat cttattttct
    18061 tagattagat gattttttat atggaataaa tttcataagt attatcttcc ttcaattttt
    18121 ccaaccaaac catctctaaa atatctagtt cttctaaata gtctttcttt gttttgttat
    18181 catcatgttt tataagttct aaaacttcaa atgtaaatgc attttcacca tattttttcc
    18241 actcattatt taactctttt atcatacatg aaccagcacc aagctgaaat ttgatagagt
    18301 taaatttgct ttttatgtca ttactttttc caaggtaaat ctttttagta atatcatttt
    18361 ttattatgaa tacacctgtg tcaaatttcc tttctttgta taattgtttt aattcacgtt
    18421 ttctatccat gattttatat acctctcttt ataattaata tgtaatatgt aaatataaaa
    18481 atatattaca tactacatta taaatatatt aattttatat gtaaatagtt tttataaatt
    18541 taattatgga ctagttatta ataaacaaga aatttagctt agtaagttca ttataaaggt
    18601 tgttataaat tttgatatta cagaaatata aaagaatagt tgacagtata gaaaatatgg
    18661 aataaactaa aaatgtaata gtaatataaa attatatatt acattgaaag gggtaaatga
    18721 ttatcatgaa taaaaaaata gaattaatag ggaattttgc aagtgattgg attaggtata
    18781 gtgattatga atatagaatt actgaagaag atgaactata tatagttcca acagaagatg
    18841 ctgtgtttag catgtacaac ccatttgatg tagcagatga tataatagta gatataattc
    18901 gtataggaca agaggcacta caagatatat caaaagagac gaaagaaatg aaattaaaga
    18961 aagaagtact tgactttgta aaaaaatatg gattattggg tttaatatac tcaagtgtat
    19021 ataatagaga tatagttgga gaagaaagag tactgatgat tgaaaagaat tatattacaa
    19081 aagaaaatat attgagtgct gatgaatatg taaacatgtt tataccattt gcaagtgatg
    19141 aagacgtgta ttttaaaaag tatagaagag gtatagatgt atcaaagaga gaagaatctc
    19201 caaagttttt tggaaagaga ccattgattt tagatttaat attttcaaag ttctacactg
    19261 aacaactaga ttggattgta agctttgcta aagatatgta taagcacttt aatcaaattt
    19321 gtgtatataa aaatacctct aatctgttaa ctgaaagtgt tactattatg tctggagggt
    19381 ttaatcccca aaagatagga ttttctataa gtcaattaga taaaccaatt attgcatggg
    19441 agtttgattc tttgaaaaca gcgattgaga ctatctatgc ttttgcaatt acaagtgaac
    19501 cttcttcttt aaataaatgt aagtactgtg gtaaaattta tattcctaca aattctaaat
    19561 ctcaatactg ttcaccttct tgtagaaatt gttcaaatgt aaagaaaagt agaagtagag
    19621 ctaaaaaaga taaataaaat taataaatat atcattgttt agattttagt aaataactgc
    19681 tgaattaaaa gttgttatag aaaattatat atctaaataa tggtattttt ttattgagaa
    19741 aatggaaaag tttaattgag atagtaattt tgagttgaca aaaactactt acaataatac
    19801 tattataagt agttgctaaa agaatgtata ttaatttaaa tataacataa aaaataaaaa
    19861 aagtcaatag aaaaaataaa aaaggagagt ttaaaaatga tatcacctat tattttgagt
    19921 tctataaatc ggaatttaaa ggaaatagaa agaaataaac tgtttgagac taatatagaa
    19981 tctagagatt atggtctaac tctttctgaa tctgatgtaa aagatataat aaattttaga
    20041 gataatactt taaaggggta tggaagaata gaattagata taaaagttac aaaacagtta
    20101 atagaaaata tatatatatc acagtataca aatatggaca attatttaga gactattaat
    20161 gatatgcaag aaatttttta ttatttaaaa aatgaaactg atgataagat atgtgatgat
    20221 gagattatag aaatactgga tgaactttat gaaaagtttt caggcaatat aaacaatgta
    20281 agaggagaag cagatgaatt tgtaaagaaa tttaaatttg gagaagttta atgtatgatg
    20341 ggagagattt gatatgtcaa ataatctaag taatattaat ataaacgaaa ataatttaat
    20401 aaagaatcag tattccatat ctttaattaa ggaatgtttt gattgtaaag ttatagatga
    20461 aagagaagta tataatatac aacaagaaat atccctaata cttatggatt tgattaaaaa
    20521 atatacaaat ggtcaaagca catcagtaaa aacagaagtt gctgaaaaat tgttgatttc
    20581 gatatggtat gctattgatt aaaaaatagc tacgcacact cgtgatttta gt
//
LOCUS       DBGJFK010000074        20491 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.074, whole genome shotgun sequence.
ACCESSION   DBGJFK010000074 DBGJFK010000000
VERSION     DBGJFK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20491
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.074"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(333..710)
                     /locus_tag="ACOIAP_002937"
     CDS             complement(333..710)
                     /locus_tag="ACOIAP_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2639815.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMEQKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFENHFKNLEEE"
     gene            complement(897..1088)
                     /locus_tag="ACOIAP_002938"
     CDS             complement(897..1088)
                     /locus_tag="ACOIAP_002938"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639816.1"
                     /translation="MGKIFGYNASAQYIGCSSGAFLGGQISAHLGIRTVFFSTSLLLF
                     MNALWMYKFTGLFIKDKTK"
     gene            complement(1046..1579)
                     /locus_tag="ACOIAP_002939"
     CDS             complement(1046..1579)
                     /locus_tag="ACOIAP_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2639817.1"
                     /translation="MFVSFIISILFVVDNFKPKEIKESISTPKKQLDILPNKFLIASI
                     FVTTFVTQLALYSIEPIVTIYISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMS
                     DKIGPQKVLLISLLWAGIIFIPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKLH
                     QKNMWGKYLDIMHLPSI"
     gene            complement(1654..1866)
                     /locus_tag="ACOIAP_002940"
     CDS             complement(1654..1866)
                     /locus_tag="ACOIAP_002940"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639818.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGS"
     gene            complement(1900..2097)
                     /locus_tag="ACOIAP_002941"
     CDS             complement(1900..2097)
                     /locus_tag="ACOIAP_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HGZ2639819.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            2583..3185
                     /locus_tag="ACOIAP_002942"
     CDS             2583..3185
                     /locus_tag="ACOIAP_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2639820.1"
                     /translation="MEVCILMGSPKKKGNTATILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKVLMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWSGKPVALITTCGYKPENGADIWENGMRRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYSILDNSIKVDNY"
     gene            complement(3461..4432)
                     /locus_tag="ACOIAP_002943"
     CDS             complement(3461..4432)
                     /locus_tag="ACOIAP_002943"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HGZ2639821.1"
                     /translation="MKKVISIGEALIDFIPNQNGCKLKNVSGFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHSLHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSDQSCKNAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGIKVNAIDTTGAGDSYIGSFLYTLLCKQITLN
                     DIKEIKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEISEFIKNL"
     gene            complement(4458..5939)
                     /locus_tag="ACOIAP_002944"
     CDS             complement(4458..5939)
                     /locus_tag="ACOIAP_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGZ2639822.1"
                     /translation="MYKEPKYRTILESTKEELNDLRNISLNDKYKPIFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDVTHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNSIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMDKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSNKKGAIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDGKDILIFSPQGLEPKGFNYQNIYNVVYAIGNMDLDNLTFEIDIMK
                     EMEKGFDFYAPQTFIKDSQTILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELVKLRYDEISGQNTIKKNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKVENTVTLDRSNFKKVFSVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NNGEAVFTSRIFAKENSNQIKIYSDKIVCYKYTKFKLKQGIEL"
     gene            complement(6031..7461)
                     /locus_tag="ACOIAP_002945"
     CDS             complement(6031..7461)
                     /locus_tag="ACOIAP_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGZ2639823.1"
                     /translation="MSAKTIDYNKVSKQLLEYIGNEQNIKGVAHCATRLRIVLDSNNK
                     ANIKAIEELEGVKGVFIASNQLQVVFGAGIVNNVYKEFSKLSGFENMSLSDVKSESTQ
                     KQNKFQQAIKSLSDVFVQIIPGLLAAALLMGITGLLGQRGIFGELSIIEMYPQLAGLN
                     RFISIASTGIFTILPLLVVYSSTMRFGGSPVLGLILGAIMLHPELTNAYSVGNGSVVP
                     EIIDLFGLKVELVGFQGGIIVALMMGFVVAKLDKFFNSKIHDMLKLFLAPICTVIVAS
                     FLLFVIVGPLGRGLANIVTSSLLWITENLGIFGYMIFAGVQQVIVITGLHHVIGAVEA
                     QLIADTGTNFIMPLMSVALIGQGGAILGYLVLNWKDIKARQIGISSFASVLFGISEPA
                     IFGVTLKYKYPLIAGCIGGAIGGAYIYMTKVTALAFGATAVPGLAIVSTQGGGHVQYI
                     LAHLVTIVVAMITTILLGKLQKKSVN"
     gene            complement(7630..8616)
                     /locus_tag="ACOIAP_002946"
     CDS             complement(7630..8616)
                     /locus_tag="ACOIAP_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGZ2639824.1"
                     /translation="MKKITINDIAGLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIIAPCLDSFVKSKIMMAIDEELKELKYTSLIINTSRKI
                     RSEIDSISKLARLKVDGIILVGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIATKGYKNIVYLGVDESDISVGSNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQKSGEMLENENPDMIICATDTIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENESAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            complement(9099..9992)
                     /locus_tag="ACOIAP_002947"
     CDS             complement(9099..9992)
                     /locus_tag="ACOIAP_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2639825.1"
                     /translation="MAKLTLEHIKGNTYYIQLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLIPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVKTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKNLI
                     DINKKKMEEIIDNIKKVCCEPVMIDKVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKVLQ"
     gene            10141..11001
                     /locus_tag="ACOIAP_002948"
     CDS             10141..11001
                     /locus_tag="ACOIAP_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGZ2639826.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPDAFIIITDIHE
                     ALGNGFKKIE"
     gene            11270..11836
                     /locus_tag="ACOIAP_002949"
     CDS             11270..11836
                     /locus_tag="ACOIAP_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HGZ2639827.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLIVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNARGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLENIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            11875..12456
                     /locus_tag="ACOIAP_002950"
     CDS             11875..12456
                     /locus_tag="ACOIAP_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HGZ2639828.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTNGKVTNDGDFIFYNNLKHVSGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(12518..13435)
                     /locus_tag="ACOIAP_002951"
     CDS             complement(12518..13435)
                     /locus_tag="ACOIAP_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HGZ2639829.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     LISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVKYGKKQARKKSRSVNSL"
     gene            13565..15193
                     /locus_tag="ACOIAP_002952"
     CDS             13565..15193
                     /locus_tag="ACOIAP_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGZ2639830.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKVIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENVKRAVVIGGGFI
                     GLEIAENLSAMGIRVSVIDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIEG
                     ENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNKTLIADEYMLTNDKDI
                     YVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPEL
                     NAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQVM
                     GPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGEL
                     DSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGKN
                     SYMAQNRLKRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            15196..16143
                     /locus_tag="ACOIAP_002953"
     CDS             15196..16143
                     /locus_tag="ACOIAP_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2639831.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTIELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHQEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEACPVKAAKLTDNGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQINRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGVDKFIEMLLSDEVLERKEDILDAPLHLTGGAVC"
     gene            complement(16420..16683)
                     /locus_tag="ACOIAP_002954"
     CDS             complement(16420..16683)
                     /locus_tag="ACOIAP_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HGZ2639832.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQKNYD
                     YYGGFAKKNPCRMRVPNTGTWYIVVNQDGNSGIVNFSINTIQN"
     gene            complement(16782..17027)
                     /locus_tag="ACOIAP_002955"
     CDS             complement(16782..17027)
                     /locus_tag="ACOIAP_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639833.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTIYKDESSDSG
                     YYALLENEEERVVWDGEVVANNIFNKLWIVVNKVKTG"
     gene            complement(17452..17820)
                     /locus_tag="ACOIAP_002956"
     CDS             complement(17452..17820)
                     /locus_tag="ACOIAP_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family (seleno)protein"
                     /protein_id="HGZ2639834.1"
                     /translation="MTRPSIYNSQGYTCAEALIKSYNEEHNTDIPISIGSGMGFGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELMNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            18249..19205
                     /locus_tag="ACOIAP_002957"
     CDS             18249..19205
                     /locus_tag="ACOIAP_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HGZ2639835.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRAKEGNPVC
                     ESGIFEILDVTDENRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EVARELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            19424..19771
                     /locus_tag="ACOIAP_002958"
     CDS             19424..19771
                     /locus_tag="ACOIAP_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639836.1"
                     /translation="MLNLKEIREEIIKKYIGDILISELTDELKSIIITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILLDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRIIISIDSYDD"
     gene            19811..>20491
                     /locus_tag="ACOIAP_002959"
     CDS             19811..>20491
                     /locus_tag="ACOIAP_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HGZ2639837.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGTELISIGGVLVDNEFNTI
                     DNYYSLVKPRYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDIIGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAMDLMNVCKCFFFNYPKNIDILEELYNKLPAFKTPLYYIPYFED
                     ENFELKFDR"
BASE COUNT         7135 a         2980 c         2624 g         7752 t
ORIGIN      
        1 tacttttagt ttacctataa taacaaaaga tagatttatg ttgtaataat taaaaatagt
       61 caaatatatt ttgatatggt taagtagaaa taatacttta gattaatgaa tattgataag
      121 ttataaaatt attttaaatt ttaaaaatca ctacttacta agataagtgg tatcatttaa
      181 cttgatactc cctattccaa ttgttttagg tattttacta attagaacct atttaatatt
      241 actttatgaa tagtgagtag ctgattaaat aataccattt atggtttgca gccatagatt
      301 aattaaattc ttaaagttct atcctaatat aattactctt cttctaaatt tttaaaatga
      361 ttttcaaata aatccaacat atctttatca acaacttcat catcatgtag tgctgaaatc
      421 aaactctgta aagaattgtc gtgtatatta cttaaaaaat cttttgtttc aacacttaaa
      481 tactccttat gtccaacaac tattgtataa tgagtgtatc tatctatttt ttctgcactt
      541 aaaaaatgtt ttttaacaag tcttgataaa agtgtcaatg tagttgtttg tttccaacca
      601 tatttttgtt ccatagcttc aatagtttct tttgatgtta ctgtatcatt tttttcccaa
      661 atgaacttca taacttttaa ttctgcttgt ggtatttttg aaattgtcat aaccttacgc
      721 ccctctcaaa cttttattaa attaatacta tcgcaatata gtttttaagt caaagatttt
      781 gtcgataata atatattcca attttttcca aataaatatt tcttatataa ttctataata
      841 aattacataa gaaatattca ttttacatca taaaattaaa aatataaata gtataattat
      901 ttagtcttat ctttaataaa caatccagta aatttataca tccaaagtgc attcataaac
      961 aacaatagac ttgttgaaaa aaatactgtt ctaatgccta aatgtgctga tatttgtccc
     1021 cctaaaaatg ctcctgatga acagcctata tactgggcag atgcattata tccaaatatt
     1081 ttccccacat attcttctgg tgcaattttt taagcaagct gttcacagaa ggattaagcc
     1141 ctgcaaccga caaccctaat aaaaatctta acaacatcag ttgccatgca gtttttacaa
     1201 aagcttgtgg tatgaatata atcccagccc ataaaagtga aattaacaat actttttgag
     1261 gtcctatctt atctgacatt tttccaagtt tttgggctgc taataaattt gctaatcctg
     1321 atgcagaaaa tgtcaatcca gctattaaag ctacatttga tgcaaaattt gtgagctgtg
     1381 atatatatat ggttacaatt ggttctatag agtataaagc taattgagta acaaatgtag
     1441 ttacaaaaat agatgcaatt aaaaacttat ttggcaatat atctaattgt tttttaggtg
     1501 tagaaattga ttcttttatt tctttaggct taaaattatc tactacaaat aaaatagaga
     1561 tgataaatga tacaaacaac aatcctcctg ttataataaa tgtactttta agacctaaga
     1621 ttgattctat atatcctcct actgttggcc caattaagaa ccagtagttg atgcagttgc
     1681 aagagtacct aaagcccatc ctgaatgatt tttatctgtc tgtgttgcaa taagagtagt
     1741 acatgcagta gcataacctg taaaaactcc ttgaagtatt cttaatccta ataactgata
     1801 aacattttga acaaacgcca tggtaaatat aactattccc atcccaatac ttgcacgcaa
     1861 aagcattgat tttctcccat atttatcagc agctttccct caaattggtg aaaaaaatgc
     1921 tgctactaca aaagtacatc caaaaattat acctgaatac tgttgtatta aactaacatc
     1981 agttaccccc aattgtttaa tatataatgg aagtataggt gctatttggc tcatccctat
     2041 agaactaaaa aacataccta tccaacatac aaataaattt ctcttccaca attccatata
     2101 gaattacacc ccctgtattt taattttttc aataatacta taagtttatt aatttatgct
     2161 attgattact caatatattc atctcttctt ttataatatt gtttaggaaa ttcataacta
     2221 gaaaataatg gtatcgataa aaaataggag taaacatggt gcattttctt ctataaattt
     2281 atagtcctca tttaagtaca tattttttta cctaaaatat ttttaatata atcataaatt
     2341 aaacaattat aattctataa gatgatttta caataaattg ccatagttaa ctacacacat
     2401 gtatgtaaaa acatacctaa aatattttta attataaata catacagact tttatgacta
     2461 aaataatttg tttcaatttt attacaaata tacaaagtat attgttgtta acgtattccc
     2521 atagtatcct aaaactatat taagcactaa aaactatttt aaaatactgt ggaggtatca
     2581 atatggaagt atgcattctt atgggaagtc ctaagaaaaa aggcaatact gctactattt
     2641 taaaaccttt tattgaggaa ttagaaaact ataattcaaa tattgaagta atctggttat
     2701 atgattgtaa gatagagcca tgtattgctt gtaaaaaatg tcaggataac ttatttgatt
     2761 ttggatgtta ttgtaaagat gatgttcaga aaattttcaa gaaagttctt atgtgtgatt
     2821 taattgtttt tgctactcca atttattctt ggtactgcac ttctccaatg aaagcactac
     2881 ttgatagatt ggtgtatgga atgaataaat actatggtaa tgaaaaaggg cctgctctat
     2941 ggtcaggaaa accagtagca cttattacaa catgtggata taaacctgaa aatggtgctg
     3001 atatttggga aaatggtatg aggcgctatt gtaagcattc acagttaaaa tacataggaa
     3061 tgcttgttga acgtgattta ggtaaaccta attttatgaa taaagaaaaa gaagaacatt
     3121 ctcgtcaatt tgcaaaacaa atttattcta ttttagataa ttcaattaaa gtagataatt
     3181 actaaatgtg taatgccata agtaaagcat tgataatata aataaatcct acataattta
     3241 cttatttaaa ataaaatatg aagtctttaa aataaagtgt gtgttttcta aaaagtgaca
     3301 ataattaaca tgttttttat catttcaaca atgataaaga ggcttacctc tattttgaga
     3361 tagcctcttt attacttttt atatatcaat tattttcata gtaaccatca tcaaaaactc
     3421 cttacatatt acttctttca aatcctatta cttgttctta ctataaattt tttataaatt
     3481 cggatatttc ttcctttgtt gcatatgaac ttatcgcacc cttaatagtt gtactacgag
     3541 ctgcataata attagaaaac tctaaatact catttaacgt ttcttgtttt atttctttta
     3601 tatcattcaa tgttatttgt ttacacaata atgtgtataa aaatgaacct atataagaat
     3661 cccctgctcc tgttgtatct attgcattta ctttaatacc tttgcacata ccttttactt
     3721 ttttagtata ggcgtctact ccatcttttc cttttgtata taatactagt tcaacattcc
     3781 ctacaaagag tttatgtagt gatttttcta tatcattttc tcctgttata aattctaatt
     3841 cttcatcaga tatcttaaca atatgagcaa aaggtaaaaa ttctgatatt gcatttttac
     3901 aagattgatc actatcccat aaaggtaatc taatattagg gtcaaaactt attatactat
     3961 tactttcaag tgcatattct attgcttttt tatgtgctaa tttcattgga ctatctatta
     4021 aatctactga acaaaaatgt aggctatgac aattattaaa ccattctttt ttaacttcat
     4081 cagcttctaa aagcatatct gcacttggat ttctataaaa tgagaaatca cgattaccat
     4141 cttcttttaa tgatacaaaa gcaagtcctg tatttgcttt acttgttctc aatacataat
     4201 cagtatttac atttacttca tttaatacat ctattatata atcaccaaat gcatctttcc
     4261 ctaacttaga tataaaactt gattttcctc caagctttgc tacaacagca ctaacatttg
     4321 ctggagctcc tcctgctact cttctaaatc ctgatacatt ttttaattta caaccatttt
     4381 gattaggtat aaagtctatt aaagcttctc ctatactaat tacttttttc atcttttcta
     4441 ccccttataa tatgttttta taattcaata ccttgcttta atttgaattt agtatactta
     4501 tagcatacta ttttatcact ataaatcttt atttgattgg aattttcttt agcaaatatt
     4561 ctactagtaa atactgcttc tccattattt ataaaaattt ctaaaatact tctatctgct
     4621 aatactttga tgttagtatt ttcatcaata tttatatatt cttttctatt tgttccatac
     4681 tcaacactga aaactttttt aaagttgctt ctgtctaaag ttacagtgtt ttctacctta
     4741 ttaaattcta attttacacc ttcatcttgt gacgaaaata attccaatcc aaatttattg
     4801 ctgtcaatat tttttatatt aatattaagt tcatatacat tttcatcatt ttcgataata
     4861 ttaatattct tttttatagt attttgtcca cttatttcat catatcttaa tttaactaat
     4921 tcatctacag gcatttgtaa tagtttatta ttttttatat ttaattttct tggaacagtt
     4981 agacaatgtg cccatttatt tttatctgta gggtataaaa cttctcccat tccagcccat
     5041 gcaaatagta tagtttgtga gtcttttata aatgtttgtg gtgcataaaa atcaaatcct
     5101 ttttccattt ctttcattat atctatttca aatgttaaat tatctaaatc catattgcca
     5161 atagcatata ctacattata tatattttga taattaaatc ctttaggttc taatccttgt
     5221 ggtgaaaata ttaatatatc ttttccatct atattaatat aatctggaca ttcccacatg
     5281 taaccaaaat cttcatctat attttttaca tttaattcac ctttaaaatt ccaatctata
     5341 gagtttttag attcatatac aattatagct ccttttttat tacttgtttg agctccaagt
     5401 agcataaagt atttatcctt tcttttaaat acttttgggt ctcttacatg tcctgtatat
     5461 ccttttggta tttcacttac tattggatta ttttcatatt tagttatttt accatccttg
     5521 tccattatag ctaaattttg atatgcatat ctatcttctg cactatattt tatatttcct
     5581 gtataataca tatgcaattt tccatctact tctatcgaat tacctgaata tgctccatga
     5641 gattcataac tttcaattgg tattaatgct acatcttctc tattccaatt tacaaaatca
     5701 tctgaactta cataagccca atgcttcatc ccatgagtta catcatatgg ataccattga
     5761 taaaatacat ggtacttacc attataatat gctaatccat ttgggtcatt aagtagccca
     5821 tgttgtggat gtatatgaaa tattggttta tatttatcat ttaaagatat atttcttaaa
     5881 tcatttaatt cttcttttgt cgattctaat attgttctat atttaggctc tttgtacata
     5941 tttttattcc ttttctttta tagttttata taatcttaga agtcattagt atatatcact
     6001 ttttatagtt atttgattat ttataattta ttaattaact gattttttct gtaattttcc
     6061 aagtaatatt gttgttatca tagctacaac tattgttact aaatgtgcta atatatattg
     6121 aacatgtcct ccaccttgag tagacactat tgctaaccct ggtaccgctg ttgctccaaa
     6181 tgccaatgct gttacttttg tcatatatat gtatgcacca cctattgctc cacctataca
     6241 ccctgctatt aatggatatt tgtactttaa agtaactcca aatatggctg gttctgatat
     6301 tccaaataat actgaagcaa atgaagatat tcctatttga cgagctttta tatctttcca
     6361 atttaatact aagtatccta atatagctcc accttgacct attaacgcta ctgacataag
     6421 aggcattata aagttagttc ctgtatctgc tataagttgt gcttcaacag ctcctataac
     6481 atggtgaagt cctgttataa ctataacttg ctgtactcca gcaaatatca tatatccaaa
     6541 tattcctaag ttttcagtta tccataataa agaggatgtt actatatttg ctaagcctct
     6601 tcccaatggg ccaactataa caaatagtaa aaatgatgct actataactg tacatattgg
     6661 tgctaagaat aacttaagca tatcatgtat ttttgagtta aagaatttat ctagtttagc
     6721 tactacaaac cccatcataa gagcaactat tattcctcct tggaatccca ccaactcaac
     6781 tttcaatcca aataaatcta ttatttctgg tactacacta ccatttccta ctgagtatgc
     6841 atttgtaagt tctggatgaa gcattatagc tcctagtatc aaacctaata ctggacttcc
     6901 tccaaatctc atagttgaag aatatactac taacagtggc aatatagtaa atattcctgt
     6961 tgatgctata cttataaatc tattaagccc tgctaattga ggatacattt ctattattga
     7021 caactctcca aatattcccc tttgacctaa aagccctgta atacccatta acaatgctgc
     7081 tgctaatagt cctggtatta tctgcacaaa tacatctgat aaagatttga tagcttgttg
     7141 gaatttgttt tgtttttgag ttgattcaga tttaacatca cttaatgaca tattttcaaa
     7201 tcctgatagt ttactaaatt ctttataaac attatttact attcctgctc caaatactac
     7261 ttgaagttga ttagatgcta taaatactcc ttttactccc tctaattctt ctattgcctt
     7321 tatatttgct ttattattac tatctaaaac aattcttaat ctcgttgcac agtgtgctac
     7381 accttttata ttttgttcat ttcctatgta ctctaataat tgctttgata ctttgttata
     7441 atcaattgtt tttgcactca tctttatctc ctctcgattt aattaaaccg gtttcgaaac
     7501 cggtttaatt aaagactatc ataaatttat tttagatgca atatttcttt cgaaaaagtt
     7561 ttcctaattt ttggaattat agtttttcta ataaaaaaat acacattact aatatatgta
     7621 atgtgtatct taatttttat ttattgtact ttcaccttct attaattcaa atttaatctc
     7681 ctttaatagt ggttcttttc tttcttgtat taagtttact atcgtatttg ctgctacttt
     7741 acctgcactt tcattttcaa attttattgt tgtaagttta gggcttataa tagacaatac
     7801 atcatatccc ccaaatccag ctacagatat gtcttgtggt atatttttac ctctcttatt
     7861 gatttccttc attgttgcta ttgctatagt atcagttgca catattatca tatctggatt
     7921 ttcattttct agcatttctc cacttttttg tatagacgtt tcttggtcaa aatcagtata
     7981 aaatactttt gcatcatatc ctttatcttt taacccatta agtactccat tttttctatt
     8041 tgaaccaact gatatatcac tttcatctac gcctaaatat acaatgtttt tgtaaccttt
     8101 agttgcaata tattgcccca ttttatatcc tgctccataa tcatcattca ctatgctatt
     8161 gataccatca actttttgtc caactacaac tattggtata tctaactttt caatttcatt
     8221 cttatgttct ttagttattt cggtaccaac taatattatt ccatcaactt tcagtctagc
     8281 taattttgat atactatcta tttctgacct tatttttcta ctagtattaa taattagtga
     8341 tgtatatttt aattctttga gttcttcatc tattgccatc ataattttag attttacaaa
     8401 agaatctaaa cacggtgcta taataccaat aaagtatgtt tttttagctc tcaaactttg
     8461 agcaaatgca ttcggctcat atccatattc atctattatt gtctttattt tctctttagt
     8521 agaatcactt atatctttat tatttagata tctcgataca gtacttttag atactcctgc
     8581 taatccagca atatcattta ttgttatttt tttcataggt tatcaccttc tacatttgat
     8641 atattttatt tcattatatt atatatttaa aataaaatat agttatttat ctcttcaatg
     8701 ctttttatac attacttgta ctatctatac aacacttaga aaagtgtttt tttcactaag
     8761 ttataatttt tatttttgtt gttatattta attatatcta ctataaattg ataaatatct
     8821 taaattattt atcacataaa aaacttgtaa aaaaaaaata tatgaaaata aggctatgat
     8881 tttcactgcc atagccttat caataaatgc ttaatctcca tttaaaaaat aaattcttaa
     8941 attataacat agtattgcgg tcaaatattt attattctag aattatcagt aactttatat
     9001 taattatttt gccttattta tataaaatct atttttatat tattttttaa ataatagcat
     9061 aactaaaata gttttatcat ataatttgaa aatttcgact attgcaaaac ttttatcatc
     9121 atcttaccac catcaaatat gtattcaacc atattatttt catataaata agttatataa
     9181 gaacgtattg tactcccaac taatacatat tgattagcat caagcttgac attgtacaaa
     9241 tcacacatct tttcaataac tttatcaatc ataactggct cacaacaaac ctttttaata
     9301 ttatctatta tttcttccat cttcttctta ttaatatcaa tcagattttt tatatctgta
     9361 gttttgacag agtgacttgg aacaaagaag tctgcctcta acattctcaa tttttctagt
     9421 gtcttaaact gtgaatctat atccaataga aagaaaaaat gatatttagt aattatattc
     9481 tctggtgtaa gactatctgc aacaaacaaa acattatctg gagttttaac accaatcatt
     9541 tcaaaataat gacctggaag agaaatcgct tcaagttctg tatctacaat tttgccattt
     9601 gaaggtataa tataatcaac ttcactttcc tttgctaata aaaatttatt cttcagtgct
     9661 ttacttggat aaccaccata taaaaatgct gattctaata ttggattttc tgtaaaatat
     9721 ccttcaattt tagttgtggc aatcttgcat tttgtttgat tcttcagata tgcatttcct
     9781 cctatatggt ctgcatttga atgagtgttt attattaatt taggaatcaa attatgttct
     9841 tctaataatc ttaaaacttg tctagctgta tccttattgt ttccactatc aattaaaatt
     9901 gcatctttac catctacata tacacctact attgtaggga gttgaatata atatgtattt
     9961 ccttttatat gttctagagt taatttagcc attttataac ctccctttaa atttactttt
    10021 aattatagca ttaattttct gaaaattcca atcaaattat ttttataata tatttttatt
    10081 tcttttatta aaaattggaa aaactatata atatatatta taatctatat ataaggagtg
    10141 atgttattga aaaaagatag aataactttt tcagaaattt taatattaat tgtaggctgt
    10201 atattaatgg caatttctct taacttattt tttaacccac atgcaatcgc tgctggtggt
    10261 ataacagggc ttggagttgt tttaaattca ctattcggtg tagaactttg gattgtcaat
    10321 ttacttttaa atgttccatt attcatattt gcttacaaaa tactttcaaa gaaagattgt
    10381 tttaaaacag ttttaggaat aatttttctt accatagcac ttaagcttac tgcgaatatg
    10441 gctacattag atataacaaa cgatatgtat cttgcaatta tatctggttc tattttaatg
    10501 ggagttggtc aaggtcttat ttttagaata aatggctcta caggtggaac tgatttaatg
    10561 gcactcctac taaataaata ttttcctaca tttagtatac ctgttttaat gggtattgtt
    10621 gactgtgttg tagttgtttt atcaggtata gtaaatagac aggttgaaat tgcactctat
    10681 tcaactgtgg ctttatatat tttagtaaaa gttagtgatt tacttattga aggatttaat
    10741 tattccaaat cattcactat tatatctgac ctttcaaaag atataagtaa aaaaataatg
    10801 gaagatttag atagaggtgc aactattcta aaaggtgaag gtgcatatac tggagaaaat
    10861 aaaaatgtac ttttagtagt agttgaaaag aaagaagttg tcgaattaaa aaaattagta
    10921 aaaaatgtcg accctgatgc attcattata attacagata tacatgaggc tttaggtaac
    10981 ggatttaaaa aaatagaata attaacagac aaatagcaag tataattaca tatataaatg
    11041 caacttttta tatgtcgtat tacacttgct atttatatat tataaaacta caaaacaatt
    11101 taaaccatat agtggcaata tgtttaaatt ataaaatatt catgtagtta tataataaat
    11161 aatttataaa tatagccaaa ttggtctaaa tacatatata atatagctaa tatacttctt
    11221 atacttgata ccatcaataa aactaaaaat ataaaaagga gaacttaaaa tgagtgttag
    11281 tttacaaaaa ggacaaagag ttagcttagt aaaagacaat aatcctgtaa aaaatctaat
    11341 tgtaggatta ggatgggata tgaataaatt gggcaaaaaa aattacgacc tagatgcatt
    11401 tgcaatagca ttgactaacc aagataaaat gaacgctaga ggtgacttag tttattttgg
    11461 aaatcttaaa cacccttcca aagctattat acacactgga gataacttaa ctggaaaagg
    11521 cgaaggtgat gatgaacaaa taattgttaa tttagaaaac atacctgaat atgtacataa
    11581 aatagttttt ggagtttcta tatacaaagc taaaaaaaga gaccaggatt ttggtcaaat
    11641 gaacaactct tttataagac taattgattc aaattcaaaa caagaattat ttaaatacaa
    11701 tcttcaagaa gacttttctg gtaaagtaac agttttggca ggagaaattt atcgtagaaa
    11761 tgaagaatgg aaatttaatg ctttaggaat tggtcaaaat gaagagcttc gtgaattaat
    11821 taatacatat aagtaataat tacaataaaa atttacaatg aggagttgat ttaaatgggt
    11881 ataactttag caaaaggaca aaaagtaagc ttaacaaaaa gtaaccctgg cctaaaaaaa
    11941 gtaatagtag gactaggatg ggatattaat aaatatgatg gtggttttga tttcgattta
    12001 gatgcttctg catttttaac tggaactaat ggaaaagtaa caaatgatgg agattttata
    12061 ttctataata atttaaaaca tgtttctgga gctgttgaat atatgggtga taatagaaca
    12121 ggtgttggtg atggtgatga tgaacaaata aatgtagact tatctaagat accccaaaat
    12181 attgctaaaa tatcatttag tgttactata aatgaagcaa ttacaagaag gcaaaatttc
    12241 ggacaagttg aaaattcata tataagaata tacaacgaag aaactaatga ggaacttatt
    12301 aaatatgaat tgggtgaaga ttttagcata gaaacagcaa tagttgtagc agaactttat
    12361 agacataacg gagagtggaa atttaatgct ttaggttctg gatttgaaga tgggcttgca
    12421 ggattatgta aaaattttgg agttaatata ggctaatgta atatatctaa ataaaaataa
    12481 gagtatatta atatactctt atttttattt agatatatta taaactgttt acactcctac
    12541 tcttctttct agcttgtttt tttccatatt ttactgaaat atcaaagaat gctgaaatat
    12601 tttctgtaaa aaacttactt ctatgatatg caatatcaaa tgttctatgt aaattaatac
    12661 cttcaatatc acaagcccac aaaagatgct tttttaaata atcctcaata agtaactcag
    12721 atataactgc aatgccaaaa ttatctacaa ctgctcttaa tatagcttca gagttataac
    12781 atgaccatct aatattcatt gggattttta attcttttaa ttgtttttct aattgtgctc
    12841 ttgtaccact tcctaattca cgcataatta gtggttgatt tgaaagttct gaaactttta
    12901 tagagtctct tttgtagaac tcatgcttat gtgaacatat aagtacgaga ttatcattaa
    12961 taatgctttt tgtaacaata tccgggtgct taatttttcc ttctacaatt gcaatatcta
    13021 attcactatt aagtaatttt tttgcaatca atcttgtatc ttctacaaat acttcaggtt
    13081 ctataagagg atttaccttg tataattcta acattattgg gcttattaga catgtaccaa
    13141 cagttactgt tgcccctact cttatacgga tattttttgc acaatgcttc atacaatcat
    13201 tcatttcttc atttacagct aaaagatgcc tcccatatcc tagaagtttt tttcctgcct
    13261 cagttaaata taattttttt gaaattctat caaataactt aacaccatac tccttttcta
    13321 tttctgaaat agcttggcta actgatgact gggtaatata catatttctt gctacttcac
    13381 tcattttacc acattcagca accttaacaa atatctcaag actacgaatt gtcatattat
    13441 cacaacctta gcaaacatta gtaaatgctt atgattttat taatatttta gtattttaca
    13501 aatacattgt caagaagtat aattttatta tagagttata aagtagattg gagtgtgata
    13561 tattgtgaaa gtattaatta taggtggagt tgctgctgga acaaaaactg ctgcaaaaat
    13621 aaaacgtgaa atgggtgata attgttctgt tacaatacta aataaaggtg atgatatttc
    13681 ttatgcaggt tgtggtcttc catattacgt tggtaaggtc attgaagata aatcatcttt
    13741 aatcgtaaat acgcctgaaa gtttttctaa actaacagga gcagaagttc gttgtggagt
    13801 tgaagttaca tctattgata gaaatgcaaa acaagtaact ttgaaaacgc tttcaacagg
    13861 agaaaaagaa aatctaagct atgataaact tgtaattgct acaggggcgg atccaataaa
    13921 accaccaata cctggaatag atttacctgg agtattcttt atgcgtactc caaatgatgc
    13981 tataaaacta agagattcta ttgaaaatgt taaaagagct gttgttattg gtggaggttt
    14041 cattggtctt gaaattgctg aaaacctttc tgcaatgggt atacgtgtaa gtgttattga
    14101 tatggctgaa catgttatgc ctggatttga tactgatttt gctgaatatg ttgaaaatca
    14161 tatggctgat aaaggcataa tgatttttac aggtgaccag gttgtgggta ttgaaggtga
    14221 aaataaagtt gaaaaacttc gtactaaaaa tagagctatt aaaacagatt tagtagttat
    14281 gtcagttgga atccgtccta acacaggttt tctaaaagac acaggtttag aatttgctcc
    14341 taataagaca cttattgcag atgaatatat gcttacaaat gataaagata tatacgtagt
    14401 tggagattgt gcttttgtaa aaaattcttt aacaaataaa cctacatggt cacctatggg
    14461 gtcatctgca aatcatgaag gtagaatttg cgcacaaaat atatctggaa aatctaaaac
    14521 ttacaatggt gttcttggaa caacagtagt aaaattacct gagctcaatg caggaaaaac
    14581 aggtctaagt aaagaaatag ctgaaaaaga gggttataat gtttgctctg taaccatagc
    14641 tactgatgat aaagctcact attatccagg tgcatctaat tttattataa gaatggttgc
    14701 tgaaaaaaat actagaaaat tattaggtgt tcaagttatg ggacctggag cggttgataa
    14761 aatagtagat atcgctgcta ctgcaataac tttgggagct gacctttatt cattagaaag
    14821 tatggacctt gcatacgcac cacctttttc aactgctatt cacccttttg tagtggcagt
    14881 aaatgtttta caaaataaac ttaatggaga acttgatagt gttttacttg acgaaattga
    14941 agattttgac agttggacta aacttgatgt ttcaaaagct ccttctattc ctagtttgcg
    15001 ttatattcct gttggtgaaa ttaacggaga aattgaaggt cttgctaagg atgaaaaaat
    15061 tcttcttata tgtgctaaag gtaaaaatag ctacatggcg caaaatcgct taaaacgctt
    15121 tggctataca aatacgaaag ttcttgaagg tggaatacta ttttatccaa atcttaaggt
    15181 aatggaggag taaatatgag taatgttaca gcagaacaaa aaaaggaagt aaaaggtaga
    15241 ggttttctac caagcagaga tggagaacat tttgcagcac gtataataac tgtaaatggt
    15301 gtaataaatg catcacaagc aaaaaaaatt gcagaagctg ctgaaaaatt cggaaatggt
    15361 caattagcat ttactactag actaacaata gaattgcctg gtgtaaaatt tgaagatatt
    15421 gaagctttaa gtgaatttat cgctagcgaa aatttaataa caggtggaac tggctcaagg
    15481 gttcgtcctg ttgtagcttg taaaggtact gtttgtgttc atggtctagc tgatacacag
    15541 gcacttgctg ctgaaataca ccaagaattt tacaaaaatt ggtacgatgt aaaactacct
    15601 cataaattta aaattggtgt tggtggatgc cctaataatt gcattaaacc tgatttaaac
    15661 gatcttggaa ttgttggtca acgtgtacct gattatgact cagaactttg tgttggttgt
    15721 aaaaaatgtg ctgttgtaga agcctgtcct gttaaagcag ctaaattaac agataatggt
    15781 aaacttgaaa tagatagtaa tctatgtaat aactgtggta agtgtataga aagttgtaat
    15841 tttgatagta ttgaagaaaa agaatctggt tataaagtct atataggagg gaaatgggga
    15901 aaatcagttc gtcctggaac acaaattaat agattatttt caaaagaaga acttatgact
    15961 ttaattgaaa aagcaattct tttatttaga gagcagggta acacaggtga acgttttgga
    16021 ataactatcg atagaatcgg tgttgataaa tttatagaaa tgcttttatc agatgaagtt
    16081 ttggaaagaa aagaagacat acttgatgct cctttacacc ttacaggtgg agctgtatgc
    16141 taacaataaa tattttagtt gtataaatat cattaacata ttgaaaaaat tttagttaag
    16201 aataatcaaa attcttatga taaatgaggc tatctcaaaa cacagataag cctctttttc
    16261 attgttgaaa tgataaagta tatttgagta taaaaaagag tgtctcataa actataaaat
    16321 tcattttgag gcacccaaat tattttataa taattgctta ttaattttat tttaaatata
    16381 taaaatgcac aaaaagtaag aatatcttat attctaaaat taattttgaa ttgtattgat
    16441 tgaaaagttt actattccac tatttccatc ttgatttact actatatacc atgttcctgt
    16501 attaggaact ctcattctac atggattttt ctttgcaaat ccaccatagt aatcataatt
    16561 tttttgattt ttaaatttca cataatttat atggtctaac aatattacat tggcttgttt
    16621 ctctaaattt acctctacaa tatccccttt ttttaggttc atcttactat aactatattc
    16681 cattgaatta ctcctccagt atcgaataat ctttgttatt tactcatctt aaatatgtaa
    16741 aaattcattt aaaatattac aaatactata caattggact attatccagt tttaacctta
    16801 tttactacaa tccaaagttt attaaaaata ttattagcaa cgacttcccc atcccataca
    16861 actctttctt cttcattttc taataaagca tagtacccag agtcagaact ttcatcttta
    16921 tagattgtaa cataaaactc ttcatcacta tattcaggta tatttttaaa gtcttcagat
    16981 attttacatg ttaatatata tccttctagt tcttcatcta taaacaaagc aattcctcca
    17041 atctctatat ttttactaat tataccatat tatgtcataa actttttatt tcgttgtaaa
    17101 attctatttt ttctttactt tataaacaat ttatatattt ttttagtttt ttactttaca
    17161 ttacactaat taattctttt gttttcttat atattccttt ataattcata aatttaacca
    17221 ttagtttata cgactttata tacgtaaaca tataatctcg cttaatatta aataatttat
    17281 atttttttga tactataatc atattttttg gtcagctatt aatttttaaa taagattact
    17341 ttaattaaaa tataataaaa ttaatttaaa aattataata aataatacct atttaaaata
    17401 tcataaaaaa aacaagtatt ttatcgaatg caaaatactt gtttcttaga attatttttg
    17461 attttttagc atatcattta gagcatcata tgtgaaattt attatttctt cacaagttac
    17521 tttatttttt ttaagagata cacatatttc tgagctgtat ttatttctta ctctattcat
    17581 taattctctt gaatacttcc ttgctatgtt ttcatctaaa ttactatttc gtccatttaa
    17641 ataccctatt ataacaactg cagcatttac agctccacaa acacttccaa cattcattcc
    17701 aaaccccatg ccacttccta ttgagattgg tatatctgtg ttgtgttcct cattataaga
    17761 ctttattaat gcctctgcac aagtgtatcc ttggctatta tatattgatg gtcttgtcat
    17821 ttttatactt cctttcaaat tttattttat atgttttact attttaaata tgctaatggt
    17881 ctctatatta tatatactat ttttgtatct ataaaatcca acctatattc actataaata
    17941 aatttatatt actttttatt tataaaatta ctttaattta aagctttact tgatatgctt
    18001 ttattatata ttaaattaat tatactttct gtgacttagt cacataatct atatataata
    18061 atttaatcta gtcttttatt gttatacaat agaccattat atattaactt ttaattttta
    18121 gacctttact gcacttaatt caattagacc atatattatt atctttaatt ctttgtattt
    18181 aaacaaaaga tttgctaaaa taaaaataag tagtactaca taaattaaac ccttaggagg
    18241 ttataaaatt gaaaaaaata cttataacag gtgcattagg acaaataggt tcagaattaa
    18301 caataaagct tagaaatgag tatggagaac aaaatgtaat tgctagttca aggagagcaa
    18361 aagaaggtaa tccagtatgt gaatctggta tatttgaaat attagatgtt acagatgaga
    18421 atcgtttttt tgaaatcgca aaaaaatatg atgtagatac tataattcac ctagcttctt
    18481 tactttctgc agttgctgaa agtaaacctc tagaagcttg gaacttaaat atgaatggat
    18541 taataaatgg tcttgaagta gctagagaat tggattgtaa attttttaca cctagttcaa
    18601 ttgctgcctt tggtgaaaat tcaccaaaaa atatgacgcc tcaagacaca ttacaaagac
    18661 ctaatactat gtatggtgta actaaagttt ctggagaatt actatgtgat tattatcatt
    18721 caaaatttgg agtagacact agaggtgtta gatttccagg tcttatttct tatgttacgc
    18781 ctcctggtgg aggaactaca gattatgcag ttgatatata ttatgaagca ttaaaaaaca
    18841 agagatataa atcttacata gcagaaggta caaaaatgga tatgatgtat atgcctgatg
    18901 cacttcaatc aatagtggat ttaatcgaag ctccagcgga taaacttatc catagaaatg
    18961 cttttaatat tactgctatg agcttttctc ctgaagaaat agctgattct ataaaaaaat
    19021 atattcctga ttttgtaata gagtatgatg tagaccctgt aagacaaagt atagctgatt
    19081 cttggcctaa ttctctagac agtagtagtg cagtaaaaga atggaacttt aagtttagtt
    19141 atgatttaga taaaatgacc aaagatatgt tagaaaaatt atcagaaaaa ggaataggta
    19201 aatagtaacc tatcattttt catcaaaata ggcaacatac tccaccttta acataagcag
    19261 ggtggagata taagcctgga atatgttaat ataagtttaa attagataaa aaatgatata
    19321 ggtgaaaact tttaatctta aaatatatcc aaataagatt caaaaataaa taatattatt
    19381 aaaaagaaag gaaaagctac tgtttaagta gcaggtacta atattgctaa atttaaaaga
    19441 aattagagag gaaataataa aaaaatacat aggtgatatt ttaatttctg aacttacaga
    19501 tgaattaaaa agtataatta taacagattt acagtctaac ccgtttaaaa gtaatattga
    19561 gctcagtata ataccagcaa atatagaaat atttaaaaaa atagaaaata tattactaga
    19621 ctctaaggtt aatttaaaaa tgggttggga aagaatactt ataaattata tcttaaaaga
    19681 tttatttgaa ttaaattatg aaataaataa aagttgcaat gaacctttga tgtttagaat
    19741 cattatatct attgattctt atgatgatta ggctcaataa ataatttacc tgaggatgtg
    19801 ctttagattt atgaaataca agttatttat agactttgaa tttaatatac tagatgataa
    19861 taaaaataaa ccaaaagaat ataatggcac tgagttaatt tctattggtg gagttttagt
    19921 tgataatgaa tttaatacaa tagataatta ttactcttta gttaagccaa gatacaataa
    19981 aatactttca aataaatgta aaaacttaac caaattgaac caactagata tcaataatgc
    20041 tcctaatctt ttatatgtta tggatgattt ttataaatgg ttttgtaaat ttgatgatgt
    20101 tacaatatat aactggggtg attttgatat aattggtctt ttaacttcat ttagagtata
    20161 taaatataca ggtaagtgct tagagttatt taatatgatg attgatattc aaccttttat
    20221 atctcaacat attacatata ataatagaat cttatctaag caaatatctt tactgaatat
    20281 gaaaaaaatt ttttctgtag aaggagatat taaacataac tcactttcgg atgctatgga
    20341 tttaatgaat gtatgtaaat gctttttctt taactaccct aaaaatatcg atattcttga
    20401 agaattatat aataaattac ctgctttcaa aacaccctta tattatatcc cctattttga
    20461 agatgaaaat tttgaactca aatttgatag a
//
LOCUS       DBGJFK010000075        20345 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.075, whole genome shotgun sequence.
ACCESSION   DBGJFK010000075 DBGJFK010000000
VERSION     DBGJFK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20345
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.075"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(186..1577)
                     /locus_tag="ACOIAP_002960"
     CDS             complement(186..1577)
                     /locus_tag="ACOIAP_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HGZ2639838.1"
                     /translation="MYKLVDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEVINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLVPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(1588..2808)
                     /locus_tag="ACOIAP_002961"
     CDS             complement(1588..2808)
                     /locus_tag="ACOIAP_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HGZ2639839.1"
                     /translation="MSKIVVNQDKITDLKRVLEICPFGAIEEKSGVVEISAGCKMCKL
                     CVKSGPKGAFEFVESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCNNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFINKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSVPEKIENATGKVTLCKIEKKDLSSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMMYKLANKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDDNQKYMASAAK"
     gene            complement(2822..3610)
                     /locus_tag="ACOIAP_002962"
     CDS             complement(2822..3610)
                     /locus_tag="ACOIAP_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HGZ2639840.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKQEKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEAKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLDTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSSALVNKLEELKLV"
     gene            complement(3627..4901)
                     /gene="larA"
                     /locus_tag="ACOIAP_002963"
     CDS             complement(3627..4901)
                     /gene="larA"
                     /locus_tag="ACOIAP_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050043 - lactate racemase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HGZ2639841.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRKINPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHVSTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSILPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSEVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMIAACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTVPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEKATSIVGKDSKVVVIPDGVSVIVK"
     gene            complement(5019..5732)
                     /locus_tag="ACOIAP_002964"
     CDS             complement(5019..5732)
                     /locus_tag="ACOIAP_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HGZ2639842.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLGDILEL
                     RIILEIEIAKLASKRITSSEAIELKNIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEK"
     gene            5857..7116
                     /locus_tag="ACOIAP_002965"
     CDS             5857..7116
                     /locus_tag="ACOIAP_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HGZ2639843.1"
                     /translation="MKKNKIIAFFAPAIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNRQISKHEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNESLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSAPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGILAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVIIIYLISAVFIAKK
                     HMKALSTNGKLMRYKNTFFIKKFSRKK"
     gene            7383..7949
                     /locus_tag="ACOIAP_002966"
     CDS             7383..7949
                     /locus_tag="ACOIAP_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2639844.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(8148..9353)
                     /locus_tag="ACOIAP_002967"
     CDS             complement(8148..9353)
                     /locus_tag="ACOIAP_002967"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGZ2639845.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNASKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNDVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDDNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRNSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILGCLDKYVDDYDIIDDEELAIFVSAKSEHEIDRFLEDVKRNNYSE
                     SVKKLLKID"
     regulatory      complement(9456..9562)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(9654..10022)
                     /locus_tag="ACOIAP_002968"
     CDS             complement(9654..10022)
                     /locus_tag="ACOIAP_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HGZ2639846.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDAKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(10074..11351)
                     /gene="obgE"
                     /locus_tag="ACOIAP_002969"
     CDS             complement(10074..11351)
                     /gene="obgE"
                     /locus_tag="ACOIAP_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGZ2639847.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELESRGYTVFKMSAATRQGVDDIIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(11462..11752)
                     /gene="rpmA"
                     /locus_tag="ACOIAP_002970"
     CDS             complement(11462..11752)
                     /gene="rpmA"
                     /locus_tag="ACOIAP_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGZ2639848.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(11766..12083)
                     /locus_tag="ACOIAP_002971"
     CDS             complement(11766..12083)
                     /locus_tag="ACOIAP_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGZ2639849.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECMVKDTHIKDAQLLLNHFQLAVEEIKREYPKNIKI
                     LKK"
     gene            complement(12098..12409)
                     /gene="rplU"
                     /locus_tag="ACOIAP_002972"
     CDS             complement(12098..12409)
                     /gene="rplU"
                     /locus_tag="ACOIAP_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGZ2639850.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(12510..13931)
                     /locus_tag="ACOIAP_002973"
     CDS             complement(12510..13931)
                     /locus_tag="ACOIAP_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HGZ2639851.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNVYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSAIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCNHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYRTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     NEVLNILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDNIEKEIMRISEHTVYKNIIVEFNDFIFEQIKGYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(13949..14650)
                     /locus_tag="ACOIAP_002974"
     CDS             complement(13949..14650)
                     /locus_tag="ACOIAP_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03936 family radical SAM-associated protein"
                     /protein_id="HGZ2639852.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPEGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKINLNTNILIPKILEIFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(14652..16496)
                     /locus_tag="ACOIAP_002975"
     CDS             complement(14652..16496)
                     /locus_tag="ACOIAP_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HGZ2639853.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            16815..18008
                     /locus_tag="ACOIAP_002976"
     CDS             16815..18008
                     /locus_tag="ACOIAP_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HGZ2639854.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDADVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(18220..18784)
                     /locus_tag="ACOIAP_002977"
                     /pseudo
     CDS             complement(18220..18784)
                     /locus_tag="ACOIAP_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438064.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18985..19776)
                     /locus_tag="ACOIAP_002978"
     CDS             complement(18985..19776)
                     /locus_tag="ACOIAP_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HGZ2639855.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLERHKSIVMWFKKVLGYISIIAFLIS
                     GFMWYYNNNLQHNMYNLGKELDGEIKQLAERHDMTKIDEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYDREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFALGLLCIIAYFILRFKISLIKNNN"
     gene            complement(19780..20109)
                     /locus_tag="ACOIAP_002979"
     CDS             complement(19780..20109)
                     /locus_tag="ACOIAP_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGZ2639856.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
BASE COUNT         6428 a         3660 c         2236 g         8021 t
ORIGIN      
        1 tatgtacaca tgtttttagg atgacaacat caacttaaat attatgttac tttctaaatt
       61 taagtaaata ttgccatcct aaaactttta aaatttagct tcaaatttaa aggtaaggtt
      121 taaaatatta catttaaatc taatttaata ttttttgttt tacaaacatt attaaattaa
      181 tatttctaat atatttttcc tgggtttaaa atatttttag ggtcaaaagc taactttata
      241 tttttaatta acatcatata agcatctgaa tttgattcat gtaagtactc ttttttagca
      301 tatcctatac catgctcacc agaaacttga ccactaagtt ctctagattt tttatacata
      361 tagtcaaaag tttcttttaa tcttattttc catgtattat catccatacc atcttttaaa
      421 atatatatgt gtagatttcc atctcctgca tgaccaaaac tttttattct tatttttaat
      481 ttgtcttgaa gctcgtgagt gtatcttata aactctgcta tcttatctct tggaacaaca
      541 acatcacatt catccatttg tgtcgtagat gcctttatag cctctaaaaa tgcacctctg
      601 gctgaccata tagaatcatt tctttcttgt gtatctgata taaatacatc taatgcacca
      661 ttttctagac ataaattagc tactttttca tattcttttt ctatatcttc agtactattt
      721 ccatcaaatg taagtaaaag ataagcatct gatgtattat ctggaaactt tttccctaaa
      781 aactcttctg ctgccagtat tacatctctt tccataaatt ctatagctgt tggtattgat
      841 tttgatttta ttattttagg aacagtttct attgccattg ataaatctgg aaatggtaca
      901 agtagactta tacttttctt tggtaaagga agcaatttta atatagcttt agtaactatt
      961 cctaaagtac cttctgaacc tactaataag tcctttatac tatatccaga actattttta
     1021 accacctttc cacctacatt tataacttct ccatttggta gtacaacttc aagacctctt
     1081 acataatctc ttgtaacgcc atattttact gccctcatac cacctgcatt agtgtttata
     1141 ttacctgcaa ttgtagcact tttttcacct gggtcaggtg ggtaaaataa atctctatct
     1201 tgaacatatt gacctattgt catcaacaaa acacctggtt ctactgtcaa tgttaaattt
     1261 tcataatcaa cctcaagtat tttattcatt ttacatagat taatcattat tccaccattt
     1321 atggcaacag cagcacctac aagaccagta ccttgacctc ttggtgtgac tggtatatta
     1381 tttttatatg cgtatttcat tattttagat acttgttcag tttcaagcac atttactaaa
     1441 acttcagggt acttctcaat ccctccaagt tcatcatgtg aaaaatcttc atttatatca
     1501 cttccaacta atacattttc ttctccacaa gtatctatta aaaaatctat atctttttta
     1561 tcgactaatt tatacatttc tatcccccta tttagctgct gatgccatat atttttgatt
     1621 atcatctttg ttattttcta ttttttcaat caatttagga ataatatcat aaatatcacc
     1681 tattaaagct agatgtgcta catcaagtat aggcgcctta tcatctttat ttattgctac
     1741 tatatagtca gccccctgca ttcctgcaac aaattgaact gctccagata caccacaagt
     1801 tattatcagt ttaggtttta cagttctacc gctaagacct atttgttttt tagcatctat
     1861 ccagcctgct tctattacag gtcttgttcc tgccacttga gcatttaact tattagctaa
     1921 cttatacatc atctccatat cttcttgttt ttttattgct ctacttgcca caactatcac
     1981 ttctgcttct tccagaccaa cttctttatt tttttctttt acacttagta ctttaatttt
     2041 agaacttagg tctttttttt ctattttaca taaagttacc tttcctgtgg cattctctat
     2101 tttttctggt actgaaaata ttttatatct tacagttgca aattgtggtc tattattagg
     2161 tgtatttata tgagccatta tatttccacc aaatgctggt cttatttggt ctaaatcagt
     2221 atttgattga atatcaagta ttgtacaatc ggctgtaaga cctgttctaa atctagcagc
     2281 aagtcttggt gctaatgacc tacctaatgt agttccacca actaacacta tcgttggttt
     2341 tattttattt ataaagtttt ctattgcttt tgaatatggt tctatcctaa aatctttaaa
     2401 ttcatcttca tcatatacaa atacttcatc cacaccataa gaaatcaaat tattacattt
     2461 atcttttatg tcttttccaa caaatacaca atacacaggt tgttttattt ttgatgccat
     2521 ctcacgagct ttacctataa gctcatatgt tacaggatgt atatttccat tatgatgttc
     2581 aacatatact gcgattcccc tccattcatc tttattaatt tgtactttac tactctctac
     2641 aaattcaaat gcaccttttg gtccactttt gacacacaat ttacacatct tacagccagc
     2701 acttatttct actacacctg acttttcttc tatagctcca aaaggacata tttctaatac
     2761 tctctttaag tcagttattt tatcttgatt tacaacaatc tttgacattt attaatcccc
     2821 cttacaccaa ctttaattcc tctaatttat ttacaagtgc agaacttagt tcatctgcat
     2881 ttcctcttac aatattttta tctgtattcg gctttggagg aaatattctt acaacttgag
     2941 taggagaacc attgagtcca tagttatttt catctttatc ttcaaagtca tctaagctat
     3001 atacaggtat ttctctatct ttagtatcaa gttttaattt aaatgaaggt agtcttggtt
     3061 gaaaaatatc tttttctaca gttattaaac atggatattc aatttcacat acttgtaaat
     3121 catttggcat atctatttca acaactatac tttcatcttt agcttcaatt aattttgtaa
     3181 cattagtaac atgaggtata tctaaaaact cagctacttc aggtcctacc tgtgctgtat
     3241 caccatcagt agtttgtttt ccacaaatta ttaggtctac ctttcccatc ttcttaatac
     3301 cctgtgatat ggtataggaa gtagccaata catctgcccc tccaaatctc ctatcactta
     3361 ttaatgctcc ttcatcagct cccatcataa aactttcttc aattactttc tttgcctgag
     3421 gaggacccat gctaagtact tttagattag ctttcttctc ttgctttatt ctaagagctg
     3481 tttctaaagc atataggtca tagggattca tttttgaatc tactccatct ctttttagta
     3541 ctcctgtagt ttcatcaact tctactgaag tcgttccagg aacttgttta atacatgtca
     3601 aaatttccat aaagtacact ccttttttat ttaactataa ctgatactcc atcaggtata
     3661 actactacct tgctatcctt accaactata ctagttgcct tttctaaagc ttctttaaaa
     3721 ttaaatgcat gtttcatatg catttttttt atcatttcag gattacactt atctgttacc
     3781 attatcacag tatatttaga taatattctc gctagtatct gaaattccca ttggtctgga
     3841 accgtatcta ctctatcaac acttctaatt ttatctaaaa gttgttttgg agaatctgcg
     3901 tttgctacat tttcataaaa agattgacca ccatgaccat cattacatgc tgcaatcatt
     3961 attattactc caccatcttt gcaggtagct tcagccgctg tcatcccttt aacagattga
     4021 taaatatttt ggtccagtgg atatccacca tttgtagtta caacaatatc agattttata
     4081 gaatttactt ctgatagctc tgttacaaat ctacatcctt tagtgtgtgc tttttcgaca
     4141 tcaccagcaa aagaagcaat tattttttta tctttatcta ttacaacatt caatatgaat
     4201 gctaattttg caactttagc tgcatatacc atatcctcat gaataggatt attgttcaat
     4261 ttcccagttc ttgaattatc actgtctata aagtcactac aatggttgta cattatagtc
     4321 tttgcagatg ctattcctgg aagtatgctt tttctcccac ctgaaaaacc tgcaaagaaa
     4381 tgaggttcta taaaaccttc tgctattaaa agttctgcct catatgctaa tttgtttata
     4441 tataaatctc cacctgaagg taatattcct actttgcaca tagatttatc atcagtagat
     4501 acatgcataa ctatatcttc attatctact atttcttctc ccattttata aattagctct
     4561 tcccttgtac ttggcctgtg aaatccagtt gccactataa tcttcacatc aatttctgga
     4621 ttaatcttcc taatccttct taatataatt ggcatagtta ttctacttgg tacaggtctt
     4681 gtatggtcac ttgtaattat gactacattc tttttcccct taactagttc ttccagagaa
     4741 ttagagccta taggattatt catagattct tcaactatct cttcttgggt cttatgttct
     4801 atataattat ccgattttga ctccaaaaca ccgagaaaac gttcatcagg tatttctaaa
     4861 atcattcctt gttttgaata cggtactttt aactttacca tttttaatct cccattataa
     4921 tagactataa aattggtatg tggtcatacc agttttacat ttatatgata gtaccattat
     4981 ctaatatttt caagaataat ttattttata acaaactttt atttttcatt ttttctataa
     5041 tttttactta taaaatccat atgttccttt gctttctcac atgcaagttc tacatcattt
     5101 tctacaactg cattgtatat agcttcatgc tgtttaagta atatgttttc attgaaaggt
     5161 tctgcgatta ttttttctct tgcatcttct ataaatccat caaataattt tgatgctgtc
     5221 ataaaaagac tttgaattaa ataattttta cttaatgttg ctagtttact gtgaaatttt
     5281 tggtctaata aaaccagtac tcgattatta tcttttttat tagtttctac cctcatttca
     5341 tctattatat ttttcaattc tatagcttct gaagaagtta ttctctttga agcaagtttt
     5401 gcaatctcaa tttctaggat tattctaagc tctaatatat ctccaagtgt accattatta
     5461 agtttaaaaa tcatagataa aggttctatt aaagtttttt ctatatttgt acatataaaa
     5521 tttccttccc cttgtctgct ttctatcact cccatagtct ctaatactct aatagcttct
     5581 ctgatggaag ttctactcac attcatttgt tcagatagtt ctctttctga tagtaattta
     5641 tccccttttt ttaactcccc atttagtatt ttatattgta tttgctcaat tacttgttca
     5701 taaacttttt tactagctat actattaaac atttttccct ccagtatgat aatcgttgtt
     5761 gtaacatata tctattatat atcttaagcc attacattca tatattttta ttacttttaa
     5821 tataatatct tataactcaa atttacaggt gatattatga aaaaaaataa aattattgct
     5881 ttttttgctc cagctattat agttggagtt ctagttttag ggattatcct atacccaaat
     5941 gaagctataa aatctgcaag agaaggcttc tctatatggt ctaatgtttt agttccatca
     6001 ctactaccat ttataattgg agcaaactta attgttgatt taaaaatagt ggatattata
     6061 gggtttatta tcaatcccat aactagattt gtatttaatg tttcaggaaa gagcgcttta
     6121 gcttttgcta tatctacagt atctggttat ccagtaggag taagtttagc ttctgaattt
     6181 aggagtaata ggcaaatttc taagcatgaa gcacaaagac tagtgtcttt ttgttctaca
     6241 tcaggacctt tattcataat aggctcggtt ggtacaggta tgttccaaaa ttcaaactta
     6301 ggttatttaa tgattctttg tcattatcta gggactatat tggttggtct tttctttaga
     6361 aattatggta atgaaagtct tccaaagacg aaattagatt taaaaacaaa cataaaaaat
     6421 gtaatcaaca ttagaaattc aagtgggaat ggtttttttg ttttatttgg aaatgctgta
     6481 tttaacggag taaatacatt acttacagtt ggtggatttg taattgtttt ttcagtggta
     6541 tttaaaatac tctctctttt taatgtaatc tcattaatag catcagttat atatttaccg
     6601 ctttcatttt taggtgttag taaagaactc tgtcaagcat ttgtaagtgg tctatttgaa
     6661 attactatag gatgtaataa agtatctagt ataacaagtg ctccagaaat tctaagagca
     6721 tctttagcta gctttttgat aggatttagt ggattatcta ttctagctca gtgttgtaca
     6781 tttctatcaa aaacagacat agatttaaaa ttatacatac taagtaagtt tgcacatgga
     6841 attttagctg ctatctttat atttatactt tatccaattg caaactctgc tgtattagtt
     6901 tctagctttg ctgatacata caacgttata tacaataatt taatctggtt ttattatctt
     6961 agctattacg atacaattct tcaaattgta ataataattt atctaatctc agccgtattt
     7021 attgcaaaaa aacatatgaa agctttatct acaaatggga aactaatgag atataaaaat
     7081 acttttttca tcaagaaatt ttcacgaaaa aaataaaaat aataaaactt tactaaatac
     7141 ttccattttt ttattatatt tgtcataatt ttaataacct ttttaattag tttaacaaca
     7201 tagttatttc atcacaattt aataatttta ttagaaatat ttttcaaaaa ttctccttaa
     7261 taacatatat cacacttgta taagtttact ggcaaatttt tccattatat aatatttcat
     7321 ttatattata taataaatac cgacctaaac ttaccaaatc aaactaagag gagtggttga
     7381 aaatggcaac aagacctata gaaatagacg aatataaaaa gataatggaa ctattacata
     7441 ctggctttac ttatagtgaa aatggcgttg aaaaaagatt tagaaaaaat cctaaagttg
     7501 cattggcact aatgttagaa gctaatttag gtctaagaat atcagatatt ttaagattaa
     7561 agataggtaa ttttaaaggt aatatgttag aaataaatga aaaaaagaca ggcaaattac
     7621 agtatagacc agttaataaa aatataattg agtccataaa tgaacatgca agaaagtata
     7681 atcttaaatc aaatgactac ttagtaaata taaagacaaa agctattcag aaacagttga
     7741 ggataatttg taaacactta aatctgtata atataagtac acatagcttt agaaagctct
     7801 atgctactac tcaatttgaa aagagtaaca ataatttaga gttggttaag gagcttttaa
     7861 atcacagctc tgtggctact acacagcgat atataagggt aactcagcaa gctattaatg
     7921 aggctagtga aaatttcttt attggttaaa ttataacgta tacatttttc tattatctta
     7981 ttaattcacc agatataaaa aaagagtgtc ttatgaacta aaaagttcat aagacactct
     8041 ttttttataa agtcaaatat attttcatta tttcaacact ggaaaagagg cttatttctc
     8101 tattttaaaa cagcttctta aattttcata attcctgcat aaaaatatta atctatcttc
     8161 aataattttt taaccgattc actataatta tttcttttta catcttccaa aaatctatca
     8221 atctcatgtt ctgactttgc acttacaaaa atcgctaatt cttcatcatc tataatatca
     8281 taatcatcta catatttatc taaacatcct aaaattccat ctttattgtt ataaccacca
     8341 aatctaacta ctgcactaca ctcatcttct ataagtccac ttaaatctaa ttttcctttt
     8401 gaaaaagact ttatatttga atttctatta tctattatat ctataatatc tgcataaaca
     8461 gcacttcctg ttgcacctct tccagctccc ttacctacaa aagaaagttc acctactgaa
     8521 tcacctacta aaataactac gttgaactca ttatctatct ttgaaagcat attattatca
     8581 tctactaatg ctggtctaac aaatccactt acttctcctg attcatactt acttctagca
     8641 accaatttta tcttacaatt taattttttt gcatactcta tatctttttc atctattgaa
     8701 gttattcctt ctaataataa atctttccaa tatactattt ttccataaga taaagtagac
     8761 aatatagata actttctagc actatcatat cctaaaacat ctgcatctgg attaacttct
     8821 gcaaatccca actcttgtgc ttgttttaaa gccacatcat atggtaaatt ttcatcatac
     8881 atctttgata atataaaatt acaagtccca tttaaaatag catttatact ctttatatta
     8941 ttgccttcca gtgattctat caatggtttt aaaactggaa taccacctgc tacagatgct
     9001 tcaaacttga tgctaacatc atttaagtta gctagttcta taaggtcgct acctttttca
     9061 gccagtaaat ctttattagc tgttactaca tgtatttttt tatttaatgc tcttgttaca
     9121 taatcaaaag ctggatttaa tcctccaatt acttcaacta gtatatcaat atccttgtca
     9181 aatatatcct ctatatcagt agttatctta tcaaaatact tcttatactt gtgtttttct
     9241 ttatttttaa ctaaaatccc aacaacttct atatctcttt ttgaagcatt attttctatt
     9301 aaatcaatta atccacttcc tactgttcca taccctaata ttgctatctt cactgtaaca
     9361 tacccccatc attttgatta tattaaatta tttatatata taaatatacc aattaaaaaa
     9421 gcttgagtat aaactcaagc catatgacgg gtttatactc atctttcagc ataaatgctg
     9481 caggatttag caccaatgta taattaaata tactggttgc cgggcttcac agggccagtc
     9541 cctctgccac tcttgataag attgctaatt taaatttatg tttaatagta taatacaatt
     9601 tctcccaatt gtcactattt ttttaactta tttctttaaa aggatataaa ctattatcta
     9661 acagctcttt tagttggttt accctttttt gtaacattat tatttttagt ctttgctttc
     9721 gcctgttcat gtcctggaaa aagtatttta ggctcttcaa tgtttctctt gtaaatagta
     9781 aatttaaaac caatagcctg cacaaattca gctcttaaag cttcacatac tgcattagca
     9841 gtttctttag catcaagacc tgcattttct aatatagtaa cttttaccaa ttccctagtt
     9901 cttaacatac catctaattg ctctaagaag ctctctgtaa caccttcttt accaatttgt
     9961 gtagtaggct ttaaagtatt tgccaaagat cttaaatacg ccctttgttt cccttttaac
    10021 atattctcac ctctataatt ctatacttaa attatctgta atctatattt aaattaattg
    10081 taaaactcaa attctaattc ataaatttta actacatctc catcttctat tcccatttct
    10141 ctaagcctgt caaaaacacc ttgactctcc atagcttttt ggaaatattg aagtgattcc
    10201 atatcatcaa aatttacaga atacattatt cttctaagtg ctttacctgt aactacatac
    10261 acaccatctt caatatctat acttagctct tcttcagttc caatatcaag ttctggtcta
    10321 tacatttctt cttctgaaac cagctccaca tcttctactt cttttagcat tttagaaaca
    10381 tatgctatta tatcatctac gccttgacga gttgctgctg acattttaaa tactgtatat
    10441 cctctgcttt ctaattcact cttaaacttc tcaaacttac tttcatcttc taatatatca
    10501 aatttatttg caactacaac ttgtggtctc tttgaaagct tttcattgta caatttaagc
    10561 tcatcattta tcttgtcaaa atcttcaata gggtctcttc cttctaaccc agatatatct
    10621 acaatatgta tcaatacctt tgttctctca acatgtctta aaaactcatg acctaatcct
    10681 atgccttcag aagcaccctc tataattcca ggtatatctg caagtacaaa actatctcca
    10741 aacttagttt gaacaacacc tagatttggt gtaagtgttg taaaatgata gtttgcaatt
    10801 tttggtttag ctttagttac aactgataga aatgttgatt tgcctacatt tggaaatcct
    10861 aaaagaccga catctgctat cattttaagt tcaagagtta tccatctttc ttctccatct
    10921 gtaccagatt ttgcaaaagc tggagcttgc cttactgcat ttgcaaagtg ttgattacct
    10981 ttaccaccta taccaccttt ggcaactata gctgtatctc cttctttttt taaatctgct
    11041 agtacaagac ctgtagcctc atctcttatt actgtacctg ctggtacttt taatactaaa
    11101 ttttctccat ttttaccagc tctcttacct ttgcttccgt cgccaccatt ttgagcttga
    11161 tattttttct ggtacttaaa gtccattaga gttctaagac ctaaatcaac ttcaaatatg
    11221 atgcttgctc cacgaccacc atctccacca tctggaccac cagctggaac gtatttttct
    11281 cttctaaatg ctaccgaacc atttccacca tttccagcct taacaaatat tcttgcctta
    11341 tctataaaca aattcttcac ctacttaatt aaaaactttt aattagcatt accaaaaata
    11401 ccattataaa ttcatcagta ttataagaaa aaggagtgcc tcaacactcc ttttatgtat
    11461 attactcagc tattgctact ggatatatac taactttttt tctcttcttg tcttttcttt
    11521 cgaatttaac agtaccatca actaatgcaa ataaagtatc atcgctacct tttccaacat
    11581 tagttcctgg atgtatttta gttcctcttt gtctaactat tatacttcca gcagttacta
    11641 attgaccatc gaatctctta acacctaatc ttttagatat agaatctcta ccatttttag
    11701 aagaacctac ccctttttta gatgctaata attgtaaatt catgtttaac atatggagtc
    11761 accccctact tttttaaaat ttttatattt tttgggtatt cccgtttaat ttcttcaacc
    11821 gctaattgaa aatgatttag taataattgt gcgtctttta tatgcgtatc tttaaccata
    11881 cactctatat gaccctcttc tcctactact ttttcaaatt caatcttttg taatttgtct
    11941 aaagaattta taactgcaat agcattagat gtaactgcag cacatactat atcatagcct
    12001 atttcagcaa aatcagcatg tccctttaaa caaaaacctt gtaacaagaa atcatcatta
    12061 taataatatt taacctttat cataacttaa ccaattacta agcgtttatt ttttctacaa
    12121 ctatcttagt gtatgattga cgatgtcctt gttttcttct gtaatctttt tttgctttat
    12181 acttgaaaac tataactttc ttagctttac cttgttcaac aactttagct tgaacagatg
    12241 ctccttctac tactggagaa cctaatttta attctccatc tttagagcaa gctaatactt
    12301 cgtttaaagt aacaacatca cctgcgttag cttctaattt ttcaacgaat aatacatcac
    12361 cttcagaaac tttatattgc tttccaccag tctttactat agcgtacatt aaatacacct
    12421 cctcggcctc aaactcgcca gtacaaggta cttcatttga agatttaaac ctttactgtg
    12481 cggcattaca attattaatt ataaaatatt tacattttat tgtcaactat tttatcgaaa
    12541 ataacattgg ttttattgtg ctttaatgta ctatttgcgt ttaaagaaat ctttatatta
    12601 tatttttcac caattttatc aattatatcc atataatatc cttttatttg ttcaaaaata
    12661 aaatcattaa actctactat tatatttttg taaacagtgt gctcacttat tctcataatt
    12721 tctttttcaa tattatctag tatataatgt acagatttta ttgtttgttc accatcacaa
    12781 catggacaag acattaaata atacttatca atggattctt tttctctacg cctagcaact
    12841 tctactaaac caagctttgt catacctaat acttcagctt ttcttttatc tttattaaat
    12901 tcttcttcta ggatgtttaa aacttcattt tgatgcttct ttttatgcat gtcgataaaa
    12961 tcaattatta ttattccagc tatatctcta attctaagtt gccttacaat ttcttttgca
    13021 gcctcaagat tcgttctata aacggtttcg tcaagtttac cagttccaat aaacttacct
    13081 gtatttacat ctataactgt aagagcttct gttttttcaa ttattaaata acctccactc
    13141 tttaaccata cttttttatt taataatttt tctattttag attctattct gtataaatca
    13201 aatacatctc tattttcctc aagacacagt ttatcaacat aagtcttatc tatacctctt
    13261 aaaatagact taagttcaga gtacttatcg taactattgg taattataga ttcaatatca
    13321 tcattcacat tatcttttac gtatttagtt gcaaaatcta aagacttata taataatttc
    13381 ggacctatac caagtttata ttcttttaaa atgttttcat actttaattt taactcttct
    13441 atatctttct ttatttcatc atgattacaa ccttgagcct cagttcttat tattaatcct
    13501 agattttcct tatttactgc cttagtaatt ttttttaatc taaatcgctc tttttcatca
    13561 gtaattttat ttgatattgt agttctatca ttggaaggta tatagacaat ataccttcca
    13621 gaaatactaa tctcagtgtt taattttgca cctttagttc ctatttcttc tttatttatc
    13681 tgaaccaaaa tatcctgacc agactttata gcacttccct tttttaattg taaataagca
    13741 agtttcttaa atccaatatc tacaaaacaa gcttctattc ctggtataac tttttttacg
    13801 attccacgat atacattgga tacagtcttc ttatttaaat tgtcttcaac aaaaagttct
    13861 gttaatcttt catcttcaag tactgctgtt ttctgagacc ctattaggga ctcaataact
    13921 atctttttca caacttcacc tctcgagctt acataggagt cactaattcc ccatcttcta
    13981 atacatataa atctcttctc aatatatcaa catctaatgg gtcaatatca agttcaaata
    14041 tctctaatat ctttggtata agtatattag tatttaaatt aatttttgag cctgtagcta
    14101 tagtagcagt aagagtaata tgttcatctt ctaaatttaa aacatcaaag gttcttatca
    14161 tgggtcttat atctacttca accatcttac cttttttatt cttttttgtt atgattattt
    14221 ctttattatt cataaagtca attacttttc tttttacaaa ctctttggtc ataggtcttt
    14281 tcaaatctat attaaacaaa tattctccat aatctataac agaagaaaga gaaggtgttt
    14341 gtctatcaat ttcttttgct ttgataaaat ctatcccctc tggaagttgg attgatactt
    14401 tatttaaaaa ttcctctact gataaatcat cttcttctat ctcaatatct acatactcac
    14461 cctgactttc tgttcctaaa gccaaagcat taccataact catcttaggg tgaggattaa
    14521 atccttgaga atgtgataag tttatttcag ctcttctaaa tgctctttgt aataatctct
    14581 gaaggtcaag atgtgatata tatatcatat cgccttcctt tttaaatttt actcttatta
    14641 tcttactcat attagcaaag cccccttcct atatcatgta tatttattcc acagccattg
    14701 cagttatgtc tacaatcaga agtgattttt tcttttttag cattttcatc ttctctaatt
    14761 aagaattttt tactaatacc tacatctata tggtcccaag gaaatacctc ttcataattt
    14821 ctatttctat gtgcataaaa atctatagaa agattattct tttccatagc ttctttccat
    14881 atatctaaat taaagtgctc tgcccatcca tcaaatttag cgcctagtct aaacgcatca
    14941 tatatcactt ttcctattct tctatctcct ctagctacta ctgcttccat caaactagtc
    15001 tttgaatcat ggtaattgta ttttatattg ttgtttctta atttatttac taaatgtctt
    15061 tgcttattaa tcacttcttc tgtagtgtct tgaccatgcc attgaaaagg tgtaaatggc
    15121 tttggtacaa atgtagaagt actcactgta acactaaaac ttctctttag ctttcctcca
    15181 tttacttttc tataaatatc aataacttta taagctaatt tagctatacc atctaaatct
    15241 tcataagtct cagttggtaa accaatcata aaatacaact taacactatt ccatcccatc
    15301 tcaaaagctc tttctgttgc attttccaaa tcttcttccg taacaccttt atttataaca
    15361 tctctaagtc tttgagttcc tgcttctgga gcaaaagtaa gcccagactt tcttacttgc
    15421 tgtattttgt cagcaatttc cattgagaag ttatctaatc taagggatgg aagtgaaata
    15481 ccaatattat tagatgcata ttcatccacc aaataatcag taagctctga taacttacta
    15541 taatcactcg tactaagtga tgataatgat atttcatcat atccagtatt cttaactaat
    15601 ttatccaata tttctttaag tcttttgaca ctcttttctc ttattggtct gtatatcata
    15661 cctgcttgac agaatctaca tcctctagtg catcctctaa ataattctag tactattcta
    15721 tcatgaacag tatctatata aggtactatt agtttttctg gataatctac agtctcaaca
    15781 tcttttatta tccttttagt aggattttta gtaatccctt ccctgttagg agttacactt
    15841 tgaactgtac catcttcatt gtacttgaca tcataaaaac ttggtatgta tactccttct
    15901 atactagata ttttatataa aaaatcttct ctagtcgttt tatttttctt ccattcttta
    15961 tactcattta ctacttctaa attaacttct tcaccttcac ctaatattac tacatctaca
    16021 aaatctgcta agggttcaga attataagca caaggaccac caaccattat aaatgggtct
    16081 tccaaagttc tttcttcttt taatattggt atattggcta aatctaatat atttaatata
    16141 ttagtatatg aaagttcata ttgaagtgta aaagtaacaa aatcaaagtt tgttataggc
    16201 tctcttgact ctaatgcaaa taatggtata cttttttctc tcattatatt ttccatatca
    16261 actgcaggag aatacactct ctcacaaaat acatcttcat ccttatttat tacatcatat
    16321 aatatatgac tccctaagtg actcatacca acttcatata aatctggaaa gcaatgtgca
    16381 tatcttatca attcactatt actagtatct ttatgaattg aatttatttc atttccaaga
    16441 tatctagcag gcttttctac tttttttaag atttttttca agtctacttt attcatttat
    16501 taaaactcct ccaaacaagc tctttatttt tattcttatt tataagtaat attatacacg
    16561 ataaaatatt ttctatcaaa aatataacta aaatattgaa tttaaaatac atattattca
    16621 caaaatagaa tagttaaaaa tatttaagaa tattttctat taaattttta ttgaaataca
    16681 aattttttac aaagtatgat atattataaa cataaagcta ttgttttaca ttacttatca
    16741 tgacatctct tgttttattc accttaaaat ggggtatgtt acttatataa tgataaattt
    16801 taggagggtt aaaaatgagt aaagtttttg aagtaaaaaa agatatctac tttactggcg
    16861 tagtagatga aggtttaaaa gtattcgaca taataatgga aactgagttt gggacaactt
    16921 acaactctta tttaatcaag gacgaaaaaa cggttttatt tgacacggta aaggcaaatt
    16981 ttaaagatga gtttttaagt aatttatcag aagttactga tatagctaaa attgactatg
    17041 ttgtaattca tcatacagaa ccagaccatg caggtagttt aaaatactta ttagatataa
    17101 atcctaatat agaagtttat tgtactaaag ctgctaaact atacttagat ggtcaaataa
    17161 atagaccttt taactgtcat gtaataaaag atggtgaaat tttaaatatt ggtaaaagaa
    17221 atcttagatt tataactgct ccattcttac attgggttga tacaatgttt acttacattg
    17281 aggaggacaa gactctttta acttgtgatg catttggttg tcactttgca agtgttgatg
    17341 cagatgtagt aaatagcgaa gattacctaa aatcagctaa acactactat gattgtatag
    17401 ttaagccatt tgctaaacat gttttaagtg ctgtagataa ggtggtagga ctaaacatag
    17461 aatttgatac tatattgact tctcatggtc caatgcttac taaagaccca atggctgctg
    17521 ttaaaagata tgttgagtgg tctacagaag cggttaatac aactaatcaa aatcaagttt
    17581 ctatattcta cttatcagct tatagcaata ctttagagat ggctaaaaag ataaaagaag
    17641 ggcttgataa agaaggtgca aaggctgaat tatatgattt agaagatatg acattaacag
    17701 aaatgcacga tacactagta gtatcaaaag taatattatt aggttctcca actataaaca
    17761 aaactatggt taaacctatg tgggatttat tctctgttat agacccaatg gctaaccaag
    17821 gtaagatagc aggagtattt ggttcatttg gttggagtgg tgaaggtata actatggctg
    17881 agactttact taaatctatg tcattcaaaa tgcctgtaga atctcttaag aaaaaattct
    17941 tccctagtga agagacatta aaagagtgta tggcatttgg tgcagaattt gcaaaattag
    18001 ttaaatagcc attaatcaca catactatta tttaaaataa atgattttat atttaaaaat
    18061 aaattaaaat ggagttgtct caaaattaat ttttctaatc taattttaag ttcaactcct
    18121 tttttatttt ccaaaatgac taatataatg ataaatgcac cctcaccaag agggtgcatt
    18181 gtttataatc tgttctattt gtatactagt ataattgtat taattcacgt atctagcata
    18241 tcctacttgc cctattccag aattagatgt tgtttcacca acttctactt taataattac
    18301 attattttct ttacactttt ttaataattc tgttgtagaa aggttcttag cagtaaaatc
    18361 taaagaaaag gggttatcat attcaaaagg ataactaaca ggttcaccat ctggagctaa
    18421 tgcaaccata ccatatggta tatttataaa ccctattaca gaaattgtat gctttgatgg
    18481 gtctaaattt gaatttttgc ttataaactc cctctgctgc gttccagtta acatatgttg
    18541 tgttgttttt aatgtgattg taagcaactc taatcttagc atctgtggtc atgttctttg
    18601 taactttctt attcataaag tctgcttttg cttgtgatac tgaattaagt tgagcttata
    18661 acaactttgg agcatatata ctgttggttt cagctacata gcttttcggt gtctttgcag
    18721 tattgtcaat aatacattta aaattaaagt tgtatacact tcatacattc tcccctaaca
    18781 acattataca gattataatt tgtatattca gtacattttt tgaaaagtat aattatatca
    18841 aaatatgtga ttatgtatag atacaatcca ctatggaaaa atatataata aaagagtata
    18901 acaaacaata aaaaataaga tgattcaaat tttattttga aacatcttat ttactctaca
    18961 aattaaaatt acttggtgaa ttatttaatt attatttttt attaaagaaa ttttaaatct
    19021 taatataaaa tatgctatta tacataataa tccaagtgca aatgctactg gaattaacat
    19081 ctccgattca aagtaaaaga aatattctaa gaaaatatct ggatttacta tattcccatt
    19141 cttgtctaaa aaatctttcc cattatatcc taagtgctgt ataaaattac ttatgttatt
    19201 ataatctgct tccctatcat acaccatatt agcattcaat ccagaagaac ttaaattagt
    19261 gtttccatct ttcatatcta ttacatataa tctaagagct ttgactttac tatacttatc
    19321 tttatcaagt attttttcaa gttctaactt atattcatca atctttgtca tatcatgcct
    19381 ttctgctaat tgctttattt ctccatcaag ttcttttcct aaattataca tattatgttg
    19441 taaattatta ttgtaatacc acataaatcc agaaattaaa aatgcaatta tacttatgta
    19501 acctaatact tttttaaacc acattacaat ggatttatgc ctctccaatg ataaagatag
    19561 ttcttttatt atattacata attcatactg catttcatca ccatcatcaa atctttcaat
    19621 tgctttttta catgcttctt cttcatctaa tccttctaat ttaaattcat ttgcagattc
    19681 tataagatgg catctcattt cctgttttaa ttctatagta cttttattgt cacatttttt
    19741 atacagttta tctaaatatt catctattag tttcatgaat taatccacct ctcccaaaaa
    19801 ttgattcata acctttttaa taaatctcca ttcttgtttc tttatttcta gaaaatcttt
    19861 accttcatta gttaaattat aatattttct tcttccacct gaactttgtt cattgctata
    19921 ataagattta attaaatttt tagattccat tcttttaagt gcaagataca ttgttccttc
    19981 ttttaattca aactcacttc tttctcttac ttgctttgca atttcatatc cataacaatc
    20041 tttcttttct aatatagaaa caattaatat atcgatataa ccttttaaca cttctttatt
    20101 taactgcatt atgtaccacc gccttttcac ctactactct ataatgtata gtaattatat
    20161 ttactataat aatacatagt actatataat acaaggttta tattctataa tagacttaaa
    20221 aataataaat agctgtatat taatatttaa tctataaata ctaatataca gctatttatc
    20281 aaattttaaa aataaatttt tattttatta atgttgtcgt aacaatattt acttggtgga
    20341 aatag
//
LOCUS       DBGJFK010000076        19787 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.076, whole genome shotgun sequence.
ACCESSION   DBGJFK010000076 DBGJFK010000000
VERSION     DBGJFK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.076"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     misc_binding    186..397
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            560..1849
                     /locus_tag="ACOIAP_002980"
     CDS             560..1849
                     /locus_tag="ACOIAP_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HGZ2639857.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGIPVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIVATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSMKNNQEIDKAV"
     gene            1903..2982
                     /locus_tag="ACOIAP_002981"
     CDS             1903..2982
                     /locus_tag="ACOIAP_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HGZ2639858.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     SKSDSKGAVENILKELSGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            3003..4547
                     /locus_tag="ACOIAP_002982"
     CDS             3003..4547
                     /locus_tag="ACOIAP_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase N-terminal
                     domain-containing protein"
                     /protein_id="HGZ2639859.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKDKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGNTLTLSDIVTKLDMAFEDRKSNVENLDKEYCDEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            4737..4988
                     /locus_tag="ACOIAP_002983"
     CDS             4737..4988
                     /locus_tag="ACOIAP_002983"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGZ2639860.1"
                     /translation="MLKDLFASTIHQMLEAELDKHLDYDRYDNKNKNTKNSRNGYEQP
                     IYTYFLRFIGCLLLTGRPYNLYKFLYLYSKSLYILLQSI"
     gene            complement(5106..5648)
                     /locus_tag="ACOIAP_002984"
     CDS             complement(5106..5648)
                     /locus_tag="ACOIAP_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGZ2639861.1"
                     /translation="MKRYIALLRGINISGKNKIVMSELKAGFVELGYSAVSTYLNSGN
                     VVFLSNVDDSEVISNSIGLMIKKQFELEIPVFIISQEVLEDILNNAPSWWGDNNKEIY
                     DNLIFMFPDLSYDKFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYQKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(6097..6381)
                     /locus_tag="ACOIAP_002985"
     CDS             complement(6097..6381)
                     /locus_tag="ACOIAP_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGZ2639862.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYVL
                     VYRENEDKEKNEHDKNLNETINKFKREEEKRIQAKSAARAIAEAKKRVLY"
     gene            complement(6442..7206)
                     /locus_tag="ACOIAP_002986"
     CDS             complement(6442..7206)
                     /locus_tag="ACOIAP_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGZ2639863.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAEASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMIDTIENFRKSNKTFKEF"
     gene            complement(7488..7754)
                     /locus_tag="ACOIAP_002987"
     CDS             complement(7488..7754)
                     /locus_tag="ACOIAP_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HGZ2639864.1"
                     /translation="MIESRCGILCYECEYKEKVNCKGCTDIKKPFWGEQCPVKSCCEN
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRIVQCKKWAVLAL"
     gene            complement(7796..8605)
                     /locus_tag="ACOIAP_002988"
     CDS             complement(7796..8605)
                     /locus_tag="ACOIAP_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639865.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLVPDASGCMIFKFDKKGIESSFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKANIVDMT
                     IPILENARKQNSIMSVKSISQISCYSERHLNRIFNNSLGMSLKSYLRLLRINLVLQEI
                     QNNKIPFVTLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            8918..9199
                     /locus_tag="ACOIAP_002989"
     CDS             8918..9199
                     /locus_tag="ACOIAP_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639866.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            9464..9718
                     /locus_tag="ACOIAP_002990"
     CDS             9464..9718
                     /locus_tag="ACOIAP_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639867.1"
                     /translation="MENNDFKLTICIFAFVTGVVVLFCCIGLGEFSVEHIIQQNGGTM
                     DTDQYNIYLDQSISQYRNFGSILALLGGLGILFDKYIRKY"
     gene            9763..10086
                     /locus_tag="ACOIAP_002991"
     CDS             9763..10086
                     /locus_tag="ACOIAP_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6054 family protein"
                     /protein_id="HGZ2639868.1"
                     /translation="MATEIFTVKITPIEAQKIIKENLNADLVFSDSYNLGNDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKAISTGSAIGVLKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(10356..10550)
                     /locus_tag="ACOIAP_002992"
     CDS             complement(10356..10550)
                     /locus_tag="ACOIAP_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2639869.1"
                     /translation="MINYMIEIIYSEKISEVENILKIENIQYEFTSRDGFIFFGFYDM
                     TDAYKFETLCSDEKIQFKRI"
     gene            complement(10922..12541)
                     /locus_tag="ACOIAP_002993"
     CDS             complement(10922..12541)
                     /locus_tag="ACOIAP_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGZ2639870.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPILGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLILNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFKNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            complement(12850..13590)
                     /locus_tag="ACOIAP_002994"
     CDS             complement(12850..13590)
                     /locus_tag="ACOIAP_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2639871.1"
                     /translation="MKDFKDDIELIINDFFDCCNIPTKVFSKDLKEICSIGYDPTLET
                     YFSSLNIFSNINSTDFISNKNLFYIMLSFCDDLHFLVMPIHKFDVSSGYFIVGPFKSC
                     INNDIEFSNIPFKPLSCLDYISNLLSEICLDKMKHRPALSFYVKKTIDYIHKNYSEDI
                     TVSDICNDLQLNKSYFCSLFKKESGYTFTNFLNKVRVEKSKKYLLEKDLSILDVAVLV
                     GFNSQNYYSMVFKKFNNLTPIEYKNIYN"
     gene            13739..14488
                     /locus_tag="ACOIAP_002995"
     CDS             13739..14488
                     /locus_tag="ACOIAP_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2639872.1"
                     /translation="MKKIAIYGKGGIGKSTTTSNLSASLSHLGYKVMQIGCDPKSDST
                     KNLMKGKFIPTVLDVLKEKKEELKLEDIVFEGYGGVLCIEAGGPTPGVGCAGRGIIAA
                     FEKLEELKAFEIYNPDVVIYDVLGDVVCGGFSMPIRNGFANEVYIVTSGEMMSMYAAS
                     NISLAVDQFKNRGYASLKGLILNAKNVENERELVEKLADEIKSEVFHYIPRNKIVQQS
                     ENNGRTVIEEDENNEMSEVYIELANKIMKSN"
     gene            14530..15420
                     /locus_tag="ACOIAP_002996"
     CDS             14530..15420
                     /locus_tag="ACOIAP_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2639873.1"
                     /translation="MKLKKLCSVFLLSSLILTGCSKASDGEAKEINNNVNVVSATVAA
                     TQVLDKLDATLVGIPTTKSDLPEKYKNLPEVGQAMNPDLEIVASLKPDVFIVDSMFKE
                     NVEKSMKEYNLDTFYFETGTYTQFLKSIEDLGEKINKQSEAKKLIDELEGVEQSVAEK
                     AKKQDKKPKVAILFGGGNNFMLATKSSYLGDLVKTVGAENITDNLTDNVESDYIQFSL
                     EQILKENPDYILRFAHGNIEETKKAFDDSFDKNPAWATLDAVKNGKVIDLDSSIFNVS
                     ANIHVKDSINKLGDILYGDK"
     gene            15437..16417
                     /locus_tag="ACOIAP_002997"
     CDS             15437..16417
                     /locus_tag="ACOIAP_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGZ2639874.1"
                     /translation="MDNKKILLIVTGLITIIVLLILFSTIGSVNLSLREIFDALINEN
                     NPMVTTIVYKMRLPRNILAALVGANLAVSGLLLQAVMKNPLADPGITGISTGASVAAI
                     IILLLFPQYTNILPIVAFIGGLISCAVVYLMAYKNGLRPERIILAGVAVNTILGGVIS
                     YLSTMYSERIQSAMLWLNGSLATKTWLDVNMLIWYSIVGLIGAIFLIRSANVLQLGDD
                     AATNLGFNVNKSRFIISLVAIFLAGVSTSIVGVISFVGLIVPHITRMLLGSDHKYTIP
                     FSIILGSIVLLIADTLARTIGGSIEIPVGVIMSIIGGPFFLYLLRKRGSY"
     gene            16417..17211
                     /locus_tag="ACOIAP_002998"
     CDS             16417..17211
                     /locus_tag="ACOIAP_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639875.1"
                     /translation="MFNVKNIKIGYEDKIIIDNLSVSIKKSEIVSILGPNGSGKSTLL
                     KSLSRILKIKQGDIYIGKKNMKVMSNKEISRQVALLAQHNVSLKDIKVKDLIYYGRMP
                     HKGFFEGKNRNDDEIVTWAMRNTGLESYKDKLVSNLSGGERQRVWLAMALCQKPDILL
                     LDEPTTYLDISHQLELMELVRDINKKFKMTIIMVLHDINQASKYSDRLIIMNNGSIVA
                     DGHPNKVISEKIIKEVYKVKCDIDIDPISKKPRIHPIMLCRRTSSI"
     gene            17310..18587
                     /locus_tag="ACOIAP_002999"
     CDS             17310..18587
                     /locus_tag="ACOIAP_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase component 1"
                     /protein_id="HGZ2639876.1"
                     /translation="MYTLDVLNRLKDIDCDKDIKSLSYAVFPGTHCPLFGVVLTASYI
                     RNMALVVVGTNECTYYSKNFAYHRQFGNDSVYSVVLKDKDIVFGAEKKVVEAVKYISE
                     IGEFDAIMIVTTCVPELIGEDYNALSSELEDMLRIPVLTVNTEHYTCNSHILGMTRAL
                     RSLSSVMESYKKKEGVNILGHRQENVEDTELVKLLVKKDIKINCVIPSKCTIKDIKNA
                     SSAKLNIVTDMIALDLAEDMKNKFGIEYVYFDKNMKESIIIENYNKLCKILDIDIQDE
                     VSKQRQRYNSLLNECRYLLDGKKLIYGNTPMMAFETVDFLTELGLVPEFIQVRELYEQ
                     DNLFKDNIIKKGYNPYVSRIANIAPLRSLYENINADIYIGHENPMLLREKGLMQITLD
                     EHAQKIGFELPIGIMKTLIKLFDVEKSTRREVI"
     gene            18589..19533
                     /locus_tag="ACOIAP_003000"
     CDS             18589..19533
                     /locus_tag="ACOIAP_003000"
                     /inference="COORDINATES: protein motif:HMM:NF012375.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase component 1"
                     /protein_id="HGZ2639877.1"
                     /translation="MEIYRYFPNPSDRMGIIFIVSSINEACVIEFGPSGTTHYAIEAI
                     GSLNGEDKAKIYSTHMSESDVTFGNYDRLEKAIIEVDSNIKPKYIFVMASSVSSIIGT
                     DIIGICNILKESVNCRLIPITTGGLRDDYNQGVEEFLYILAKEVVKESSEKFDSYNII
                     GCTIDQFNFLADCEEIKRMMKAFFKKEVNVTFTSYTSIDEIENASKSSLNIVLRKEGI
                     KAAIFMKEKYSIPYVYKKPYGIKNTEEFINEIQKVTEWDLDTNTYDDEISNIKRYIFN
                     VKRKLYFYEGSKKCAVFGDYDTALGFRDLLEELGLKID"
BASE COUNT         7503 a         2313 c         3143 g         6828 t
ORIGIN      
        1 tatagataat aaagtacaaa aaaaatatat tttgatgaaa tttaaaaaaa tatattatat
       61 aaatatagta atagtatgaa aatttacata taaaactaaa aaatgcaagt aattgacttt
      121 ttaagttgac aaaatattgc atatatatta tgatataaat cataaattaa ctacaaatca
      181 atattatata ttcgtagaag aagaaagtag cataaaggaa ttttacagag agttagattt
      241 ggctgagaac taatattgga atttatgcga aaaggacttt ggagaatact attgtaacta
      301 tgttataata gtggtttaat tcgccttaag aaaatgagtg agtaaaatta atttttacta
      361 ataagagtgg taacacggat ttatattcgt ctcttggatt tttccaagag gcgtttttta
      421 ttataaactt atttcagaaa atttaaaact atatattaaa tgaaaagtat aaaaatatga
      481 tagttaataa atttataaat tagaaaattg taaaatatac taaagttagt atctttacga
      541 tttaaatgga gggatgaaaa tggaagaaga aaaaattaac tatgctctgg aacagattcc
      601 agagaatcaa aaacgtggtt gggtagctat gttttcagtt ttagtagcaa taggtgtgga
      661 tttatcatct gttattttag gagctgagtt ggcacagagt atgccaatga aacaagcaat
      721 attgtcagta attgttggtt catttttttc tgcaattttg tatactacat gctctttggt
      781 tggttcatct acaagtctat ctacatctat gataacaaag tatgtatttg gagaagctgg
      841 agcaaaaata ttttctctag ttataggagt ttctctatta ggatggtttg gagttcaagt
      901 aggtttcttt gctcaaaatg cacagataat aataaaagat atatttaatt tagatgtgag
      961 tatgcagatt ttaagcctaa taggtggtct cttgatgatg agtactgcaa tttatggata
     1021 taaggcaatg gaaaagttga gtgtgtattc agtaccgttt ttattagttc ttatgatgtt
     1081 aactatattc ttagctttta gagcaaatgg aattccagtt gatgataata tgaaatctac
     1141 tatgacattt gcaggtggag tttctctgtc aatgagtata ataatcgttg gtgcaattgt
     1201 atctcctgat ataagtcgtt gggctaaaag tagaagagac tgtgcgcttt caagcttttt
     1261 aggaatacaa tttggaaatg cttttatgat aatagtttcg atagtattag taaaatgtat
     1321 gggaacttca gatattatga gaatttttat tacattaggg attgctatac caggtataat
     1381 agtacttaca ttagctcaat ggactacaaa tacaagtaat gtatattcag catcattaag
     1441 tatagctctt gtacttaaga aggctcctga gaaagtatta actatagtcc ttggtattgt
     1501 agcaacatta ttggctgtat ttggaatata tgaaggtttt ataggatttt taaatttact
     1561 tggaattgta attgcacctg ttggtggtgt atatacagca gaatattata tagtaaagca
     1621 agaacttaaa ggctttgata aaggtgtatt atataaacca atagttaaac gttcaatagt
     1681 gtcttggata atcggtatat taataactta cctttcaaca tatggattta taactcttac
     1741 tactatagca cctttagatg gttttatagc agggtttgta gtacaatcta ttattggaaa
     1801 agtgctttgc tcaatgaaaa ataatcaaga aatagacaaa gcagtataaa gaaatttgtt
     1861 tataaagtat aaaataaatt agaaatatga ggagaaagta acatgagatt tttaacagaa
     1921 gaaagtgtag ataaaatagc agttggtgca gccgtgcttg gaactggagg tggaggtgac
     1981 ccatatgtag gtaagttggt tgcaaaacaa gccattaaaa agtatggtcc tgtaaaagta
     2041 ataagcttag atgaacttga tgatgatgct ttggtagttc cagtatctgg tatgggttct
     2101 cctgtaatta caatagaaaa attactttca gaagtagagt taactacacc tttagaaata
     2161 atggagaaat tattaaatag aaaagtggat gttataattc ctatagaaat aggaggaata
     2221 aactctctta tgccgatagc agttgcagct aaaaaaggac ttcctatttt agatgcagat
     2281 tctatgggta gagcttttcc tgaagctcaa atggtgactt tttatcttga aggatatgag
     2341 gcatctcctg ctgtaatgtc tgatgaaaaa ggaaattctg ctattcttta tcctgtagat
     2401 ggtatttggt cagaaagatt agctagaact ttaactgtag aaatgggagg aagttcttct
     2461 attagtgact ataatttaag tggagctcaa gttaaaaaag ctgctatagg taatactctt
     2521 acaatagctg aaactatagg aggattttta cttgaaagta aatctgattc aaaaggtgct
     2581 gttgagaata tactaaaaga attgagtgga tacaaattat ttgaaggaaa agtaattgat
     2641 attaagagag agttgaaagg tggatttact agaggacatg ctttttttgc tgggattaat
     2701 gaatatgatg gagagtattc tatattattc caaaatgaga acttaattgc caaaaaaggt
     2761 gatacaccac tttgtattac accagattta atagcagtgt tagatttaga aacaggattt
     2821 ccaataacta cagagagaat aaaatatggc tctcgtgtta tggtagtagc ttttccttgt
     2881 aatgaaaagt ggagaacaga aaagggaatt gagacagttg gacctggata ctttggatat
     2941 gatgtggaat ataaaacagt agaggaatta caaggaaaat aaaagtttag gaggaaattt
     3001 tgatgtatcg tgtaggaatt gacgttggag gaacaaatac agatgcttgt atactggatg
     3061 gggaattaaa agtaattcat tcagttaagg tggcaactac aaaggatgtt gaaactggtg
     3121 tttacaatgc cttaaaaaaa gttatagatg aaagtaaaat tgaccattca ttaataaaat
     3181 atgctatgct tggtacaact cattgtacaa atgctattgt agaaagaaaa agacttaata
     3241 atgtggctat gataagaata ggaaagccag caactactgc cattcttcct tttatagatt
     3301 ggccagagga cttaagagaa aaaatagagt tagattcaat attggtatct ggtggatatg
     3361 agtttgatgg tagaaagata aatgaacttt gtaaagatga agttgtagaa ttttgcaata
     3421 gaataaaaga caaagtggaa agtgttgcaa taagtggagt atttgctcca gtaaataaac
     3481 aacaagaaga agaagttgca aaatgggtta gagaaattct aggggacatt cccatatctt
     3541 tatcaaatga aataggtaat atcggtatat tagaaagaga aaatggggct attttaaatt
     3601 ctgcattgtc tcaagtaggt aaagctgtat ctttaggatt tgaaaaagca cttaaagatt
     3661 taggcataga cgctcaaata tattttagtc aaaatgatgg aacattaatg aatttagagt
     3721 atacaatgaa atacccaatt tttacaattg gatgtggaat aacaaactct ataagaggag
     3781 cttccttttt atcaaaagta aaaaatgcaa tagtactaga tgttggagga actacaagcg
     3841 acttgggtgt actatacaat ggattcccta gagaatcatc aattccagtt acaattggag
     3901 gggtacatac aaactttaga atgccagatg ttctaactat tggtcttgct ggtgggacat
     3961 gtgtaaaagg cgaaaaggat aatataaaga taggtcctga aagtgtggga tatagaataa
     4021 ctgaagatgc aataatattt ggtggaaaca ctctaacttt atcagatatt gttacaaaat
     4081 tagatatggc atttgaagat agaaaaagca atgttgaaaa cttagataaa gagtattgtg
     4141 atgaggtata taagaaggtt attttaaaat tagaagatgc tgtagaccaa atgaagacta
     4201 gtcaagatga tgttgaattg gttttaactg gcggaggaag tataattgtt cctgaaaaac
     4261 taaaaggcat aagcaatgtt ataagacctc ctcattatac tgctgcaaat gctattggtg
     4321 cagctttagg acaaataagt ggagatgtag aaaaagtata tagtttagat aaaatgtcga
     4381 gagaagatgc catagaagat gcaaaaaaag aggctgtaaa taaagctcta aaagctggtg
     4441 ctaaagaaga tactatagaa gtattaaaca tagaagatgt tccacttgca taccttcctg
     4501 ggaatgcact tcttataaaa gtaaaagttg ttggtgattt aatttaaaga ataaatataa
     4561 gtaatttcag ggtctttaaa ataaagtgtg tattcttcta aaaagtggtg ataattaaaa
     4621 ctattaaata tcactaatac aaaggaaggt gcacactttt tatgtttaac aaaaacgaaa
     4681 tataaaaaaa acttattgaa gaatatgatg taaagacaac tacagatatt caagatatgc
     4741 taaaagattt atttgcaagt acaattcatc aaatgttaga agcagagctt gacaagcatt
     4801 tagattatga cagatacgat aataagaaca aaaatactaa aaactctaga aatggatatg
     4861 aacagccgat atatacctat tttttaaggt ttattggctg tttgcttttg acaggtagac
     4921 catacaattt atacaaattc ttatatttat actctaaatc attatacatt ttattgcaaa
     4981 gcatataatc agacttagca tttctatatt tgcttttaca tctggcatat aagtgattcc
     5041 atttgtcaac taactggatt ttgtactttt tataaaaaac tattttatat agagatttct
     5101 gtcttttatc gcattccaac tatttttctt actgtatttg ctgtacgaat tgtaatctta
     5161 tcacttacat ttgaactagc agtctttgac caccaatttg tcttttgata atctttacga
     5221 ctaaaagacc aaaaaatagc atttttatag tgatacactt tttcatattc ttctttagga
     5281 tttccaacct catcataaaa cttgtcataa gataagtcag gaaacataaa aataagatta
     5341 tcatatattt ctttgttgtt atctccccac caactaggag cattatttag tatatcctct
     5401 aacacctctt gtgaaataat aaaaactggt atctccaatt caaactgttt ttttatcatt
     5461 aatcctattg aatttgagat aacctcgctg tcatctacat tacttaaaaa gacaacattg
     5521 ccactattaa ggtatgtaga aactgctgaa taaccaagtt ctacaaaccc tgcttttaat
     5581 tcagacataa ctattttgtt cttaccactt atattgatac ctcttaataa tgcgatatac
     5641 cttttcatat aataatttca cctctaaaca tttacatttt tctatgtagc acaaactgga
     5701 atttgtatct tttataattt ttttaaagct tttttatatg taatttcccc aagtataaac
     5761 tgttctaaag catttatttt tttcagattc agtattgtat ttttcaacaa ttcttctaat
     5821 aaatctattt cattcaaaat cggtttataa atatgtttac aacaattaaa ttcttcaaag
     5881 tatcttgaac caaatcatat ttgatattct acattgatat ggatttgaaa ataaggtatc
     5941 tcctgtgata aaataacagt ttttatgttt tttaacatat ttttgaagtt ctttattaat
     6001 caatttacat tctgtacatc ctttatcaaa tacaaattta catacttttt ttaatataaa
     6061 aaatcggtgc ctaatttgta ccgatttttg tttttcttag taaagaactc gcttttttgc
     6121 ttctgctata gccctagcag cactttttgc ttgtattctt ttttcttctt ctcttttaaa
     6181 tttatttatt gtttcattta gattcttatc atgttcattt ttctctttat cttcgttttc
     6241 tctgtatact aacacataat ctattattga ttcgtttatt atctgggata tacttttatt
     6301 ttcattaatt cctattctct taacttcctt aagtagagtc tcatcaatat gaaccgttgt
     6361 ttgctttgta ttttttgcca ctttaatcac ctcttaaaaa attctaacat taaaattttt
     6421 tttggtcaat aaattttaat attaaaattc tttaaatgtt ttatttgatt ttctaaaatt
     6481 ttctattgta tctatcatct tattttttat attttcacct aatacagaag actttagtct
     6541 aggattttcg atatggtcat aaattggttc taaaaattcg acttctacag gaacagaatt
     6601 aattttacca ataggttggt atccttcata agtatctttt gaatttttta ttactagtgg
     6661 aacaataggg cattttgctt tatatgctat ctttaaagct ccacttctaa actctgaaac
     6721 caatgaattt ggttctttaa tccatgttaa atctccttct ggaaacactg ccatactttg
     6781 acctgtaagt atattttgag aggcttcggc tatactcttt ataccctcac gattgttttt
     6841 tctgtttaca tatacacatc ttagtaattt tgcccattct ttaaatatag gtatatttct
     6901 ccaaactggt tcatctgcaa ttacacatcc aattggtctt tctacacttg ctgttagtat
     6961 gaagctatca agcatactag aatgatttac aacaaataga agtggttctt ttggcaatgt
     7021 ttctttacca ataatattaa gttctatatt cactatatct aaagattttt tagcttgttt
     7081 ttgcataaat tcaaattttt cttttaagct aaatttatca ggattctttt taattttaat
     7141 gagcctaggt atagaagatg taaaacctat aagttgatat gtagcaaatt ttaagtaatt
     7201 attcataaga ttatctcctt aaaataaaat tatttattac tgtaaagatt ttaacataaa
     7261 ataaaattta agtctatttt aattcaattt tctaacagat atttcaaata cacagagatt
     7321 aagattttat atttcaaatt ttagtaatca gattttatca ataagttact attctattaa
     7381 tgtaattaaa taacctttaa atttaattac aaaaactgtt gcagattttt ctacaacagc
     7441 ttaaaagact tatcttataa aaacttattt tataataaga aagtatatta taaggctagg
     7501 acagcccatt ttttacactg aacaattctt ttaccatcat caccttgttc tttgtcatat
     7561 gcaaattgat taagcatttc acatggaaat gtatcacata gaccacaatg tgtaaggttt
     7621 ttattttcac aacaagattt tacaggacat tgttcacccc aaaatggttt cttaatatct
     7681 gtacaacctt tacaattgac tttttccttg tactcacatt cataacataa aattccacat
     7741 cttgattcta tcattctaag tcactcctta aatataaatt ttatatgatt gtatatcaaa
     7801 atttatactt ttcattgtaa aaatcggaca gattttttat ataggttgtt ggattaacac
     7861 cacaaataga tttaaaatca tttataaaat gggattggtc gtaataacca atatcttgtg
     7921 ctaaagttac aaatggtatt ttattatttt gtatttcttg caacacaagg tttatacgaa
     7981 gcagtctaag gtatgattta agactcatac caagagaatt attaaaaatt ctatttaaat
     8041 gtcgttcact ataacaacta atttgggaaa tgcttttaac agacataata gagttttgtt
     8101 ttctggcatt ttcaagaatt ggtatagtca tatctactat atttgctttc aacaagtatg
     8161 ataaaaataa catatctaat tgttctacta attcttttat agtacttgtt ctttcaaaaa
     8221 tagaattaac ctctaagcta aataatgtgt taaaatcttc aagtgaaatt tttaaatctg
     8281 tagattctct ttgagaaaga cctgtcaaat aatatactcc acctgggcga aattcaacaa
     8341 atactctaaa aagtacattt tctatatcat ttttcacaat agtggttttt gttgtagctc
     8401 cccagaatga actttctata ccttttttat caaatttaaa tatcatacat ccactagcat
     8461 caggtactaa tgtaagattt tctttaatac ttgtgtctgg aatagatatt gtatagtgtg
     8521 ctatatactg tcttaacaat ttatgtggca aaatatatgt atactgtttg caggtattta
     8581 aaatgttatt gattatttta ttcataagta tatcctcctg agatataaaa aataagtata
     8641 ctaatttact ttttatataa taaaccagtt ttgatttaat tgaaatattt taataagata
     8701 ttttgttaaa tttagataca ataattgtaa ggtaaaatct caaaatatac aattattata
     8761 aatcataaat atttatcaaa taaatatatt aaagaaaagt agatataaaa caaaattaga
     8821 aaataatagt gttactttca taataaatac atataaagat atttttaaga ataaaattta
     8881 ctattaaata aaaaataaag gagagtgatt taatagtatg gcatcaaaac aaacaccaag
     8941 aaacaatttg gaaaagtttt taagaataag agtcttatca catacaggag ataaaataca
     9001 tataaagtta cctgtaaatt ttgcaaagag aatgattgag aataatgctt tggatttatt
     9061 taatggaaaa gatgatgtag tagatggtaa aaaagttact gaaatattag tcaaagcatt
     9121 tgactatgat ttaactggag aagtagttca cttagagaga aaaaatggag atattattaa
     9181 agtttcaatc gtacaataga attattttat atgaatttta tttttaaata gttataaata
     9241 attagaaatt tgtaaaaaag tataatatat tattagtaat gatgtagaat acacatttat
     9301 aatttataga tgtgtatttt ttgtttgaaa aatttaaata tataaaacta taaaggttac
     9361 aattttggaa atagatgtaa atatatgttt tatagtataa taagaagtaa tataccatct
     9421 agtaaaaata attaaataaa tttaatttat gagagggata actatggaaa ataatgattt
     9481 taaattaaca atatgtatat ttgcttttgt aactggagta gtagtattat tctgctgtat
     9541 aggtttaggt gaatttagtg tagagcatat tattcaacaa aatggtggaa ccatggatac
     9601 tgaccaatat aatatttatc tagaccaatc tatttctcaa tatagaaatt ttggttctat
     9661 attagcgttg ttaggaggac tagggatatt gtttgataaa tatatcagaa aatactaaag
     9721 attatgtttt gtttaaaata aatttttatg aggagataaa aaatggcaac agaaatattt
     9781 actgtaaaaa ttacgcctat agaagcacaa aaaataataa aagaaaatct taatgcagat
     9841 ttagttttta gtgattctta taatttagga aatgataaat ttatactgat tacaactttt
     9901 gagaagtatt atgcaagaaa caatagtgat gcagggttaa tcgtagttta tgaaaataca
     9961 acaggaaaaa cagttattaa agctatttca acaggtagtg caattggagt tttaaaaatt
    10021 gactggggtg caggtggaaa tttacttaaa agggtaaaaa atatacttgc tgattatatt
    10081 atttaattat tttatctaat tgataacatg tcaagaaaat ctcgtaaaag aggttaagaa
    10141 cattcttata atatatagat aaacaagaat ttaaaggtaa agcttttaat ctataataaa
    10201 taatattaat atagtatgaa taaaaagtag gagcatatta atataatgcc cctacttttt
    10261 tattattaaa attgtttata atattaaaac tacattaaaa tacagtctaa atttaacaaa
    10321 taaatggtgt agaaatatgt acttttttta atttattata ttcttttaaa ttgaattttt
    10381 tcatctgaac ataaagtctc aaatttgtat gcgtctgtca tatcataaaa accaaaaaat
    10441 ataaagccat cacgagaagt aaattcatat tgtatatttt caattttcaa tatattttct
    10501 acctcactta ttttttcact atatataatt tctatcatat aatttatcat tgtagaatcc
    10561 ctcctattaa tatgaaaata tccaaatata taataacata tttagatgat ataatagtat
    10621 ccaaataaaa aataaagtta tttcattatt gaatgaagaa ttaaaatgaa gataaataaa
    10681 gtaaatattg gttataatag attaaaaaat ggctatgtac acttgtaatt ttagtcatag
    10741 gaggttaaag ttttatgaaa gaagtcgtat atatatgggg tattctagtc aggaattgtt
    10801 taataataag ataatactat aaaaatttga gtattatata aaaagtaaga agccataaat
    10861 gatataagca ttatctatag cttcttattt ctcattgatt aagattatat aaaaacaata
    10921 actatatttt ttgtttaagt tttaatactt gttttactat atttgttgag tggtcagaaa
    10981 ttctttctag attagtaagt aaatcaagat aaagtacacc agcatcaatt gtacaacttc
    11041 cgttatttag tctaatcata tgtgaatttt taaaagtttt ttctaaataa tttacttcat
    11101 tttcaacttc taaaacttta tttgctaact caaaatcttt gacatctaaa actattaagg
    11161 catccttgaa attagtaatt gttttattat atatttcata tatttctctt attgcactat
    11221 cagaaaaact aatattcatt tccttaacac tcatggccaa ttcagctata ttttccgcat
    11281 ggtcagagac tctttcaatg tcatttacag tattaaaaag taaatctgtt ctaaaacgtt
    11341 catcatctct aagaggttct ttagaaagtt ttaataaata gtttaatata tctttctgta
    11401 acttattgac aactttttct gattcaaaag ctttattaat atcctcattg ctcttattta
    11461 aaaatcctgc aattgaatgt tccaaagagt ttgtagcttt atgacccatt cttacaactt
    11521 cttgtacagt attaccaagt gctatagatg gagtactaaa catcctttca tctaagtatt
    11581 tagtgttatt tactatttct gattcagttt ctttaatagg tataagtcta tttgctaatt
    11641 taactatgta tttagaaaat ggtaataata ttataacatt tgtaagatta aataaagtat
    11701 gtgcatttgc tatttgtcta gctgtatcag ttgggtcaaa atgagtaact atagctgata
    11761 taggtttatt taaaataagc ataaatatta ttgtaccaat gacattaaaa cttaagtgca
    11821 ttacagctgc acgtcgagca tttctacttg caccaacact tgataaaagt gaagtaacac
    11881 aagtacctat gttatctcca taaagaatag gcaaagcaga tgatagagga agtattcctt
    11941 gagaagctaa tgctattaac atacccatag atgcacttga actttgaaca ataccagtta
    12001 tggcgaatcc tgccaatata cctaatatag gatttttact aaaatataaa agtgcatcag
    12061 tgaatgcttt atattcagca agtggagcta ctgcatcttt cataaactcc attcctgtaa
    12121 ataatatacc aaaacctata agtatttcag ataaatgctt tgttttttga tttgatgtaa
    12181 ataaatagaa taaaatacct atacctagag caattggtgc aattccttca agattaaatg
    12241 aaactaattg agcagtaact gtagtaccta tatttgcccc cattattaca ccaatagctt
    12301 gacttagatt cattatacct gcatttacaa atcctacaac cataacagta gtagcacttg
    12361 agctttgtat aatacctgta acaactgtac ctactagtac acccataaca acattacttg
    12421 ttaagagttc aataattttt tttaatttgt ctcctgctga tttttgtaaa ccttctccca
    12481 ttaaactcat tccataaaga aaaagtccaa gtccaccgat aaggctaatt actatattca
    12541 cgatatttcc tcccttaaga aattaatgat ttttttatct gaattataaa ctttattaac
    12601 taaaatttat tgtttccata atatagaata acaaattttg tcaataagaa tattaatgtt
    12661 ttgttaagta tacgttaaga gaatgttaaa tttttaagtt gttgttaatt ttagaaaatt
    12721 tatgatgtat agcaatttaa atacttggac ttagattttt agtattttat gtacaaacaa
    12781 tttaacaaag aattaactat aattgtaaaa aatatgtaaa aaaacagcat ctttttagaa
    12841 tgatattttt tagttataaa tattcttata ttcaattggt gtaaggttat taaacttttt
    12901 aaaaaccata ctatagtaat tttgactatt gaatccaact agtaccgcaa catctaaaat
    12961 agacaaatct ttttctaata gatacttttt gcttttttca actctaactt tatttaaaaa
    13021 attagtaaaa gtatatccac tttctttttt aaacaaagaa caaaaataac ttttattaag
    13081 ttgtaagtca ttgcatatat cacttactgt tatatcttct gagtagtttt tgtgaatata
    13141 atctatagtt ttctttacat aaaaactaag cgctggtcta tgcttcattt tatcaaggca
    13201 tatttctgat aaaagatttg atatataatc taaacatgat aaaggtttaa atgggatatt
    13261 agaaaactct atatcattat tgatgcatga tttaaaagga cctacaataa agtaaccact
    13321 tgatacatca aacttatgta taggcataac taaaaaatgt aagtcatcac aaaaacttaa
    13381 cattatatag aatagatttt tattagatat aaaatctgta ctatttatat tgctaaatat
    13441 atttaaactt gaaaaatatg tttctaaagt agggtcatat ccaatactac aaatctcttt
    13501 taaatcctta ctaaatactt ttgttggaat attacaacag tcaaaaaaat cattgatgat
    13561 gagttctata tcatctttaa aatctttcaa aaaatcacct catttaaatt tatacaaata
    13621 tttttataaa aaaacaaata tagttaagaa taaaaaaaat atatcaatta aaatagttat
    13681 tgcgaatgat aattaatttc gttaaataat attatgatgt aagagaggta gaaagtcaat
    13741 gaaaaaaata gctatctatg ggaaaggagg aattggaaaa tcaacaacaa cttccaattt
    13801 atcggcatca ctttctcatt taggatataa ggtaatgcag atagggtgtg acccaaaatc
    13861 tgattccaca aaaaacttaa tgaaaggaaa atttatacca acagttcttg atgtattgaa
    13921 agaaaaaaag gaagaattaa agcttgaaga tatagtgttt gaaggttatg gaggagtatt
    13981 atgtattgaa gctggagggc caactccagg tgtaggatgt gcaggaagag gtataatagc
    14041 agcttttgaa aaattggaag aattaaaagc atttgaaata tataatccag atgtagtaat
    14101 ttatgatgtt ttaggagatg ttgtttgtgg gggcttctca atgccaataa gaaatggatt
    14161 tgcaaatgaa gtgtacatag taacttctgg agaaatgatg tcaatgtacg cagcaagtaa
    14221 tatatctttg gctgtagacc aatttaaaaa tagaggatat gcctctttaa aagggcttat
    14281 attaaatgca aaaaacgttg aaaatgaaag ggaattagtt gaaaaattgg ctgatgaaat
    14341 aaaaagtgaa gtttttcatt acataccaag aaataaaatt gtacagcagt ctgagaataa
    14401 tggacgaact gttatagaag aagatgaaaa caatgaaatg tcagaagtat atatagaact
    14461 tgcaaataaa attatgaaaa gcaactaaaa aagtatattt aaaattaagt ttattatgga
    14521 ggaaatttta tgaaattaaa aaaattatgc tcggtatttt tacttagctc attaatatta
    14581 acaggatgct caaaagcatc agatggtgag gctaaggaga taaataataa tgtaaatgtt
    14641 gtttcagcta cagtggcagc tacacaagta ttagataaat tggatgctac gttggtagga
    14701 ataccaacta ctaaatctga tttaccagaa aaatataaaa acttgccaga agtaggacag
    14761 gcaatgaatc cagacttaga gattgtagca tctctaaagc cagatgtatt tatagttgat
    14821 agtatgttta aagaaaatgt tgaaaaaagc atgaaagaat ataatttaga tactttttat
    14881 tttgaaactg gtacatatac acaatttctt aaaagtatag aagatttagg tgaaaaaata
    14941 aataaacaga gtgaagcaaa aaaacttata gatgaattag aaggagtaga acaatctgta
    15001 gcagaaaaag caaaaaaaca agataaaaaa ccaaaagtag caatcttatt tggtggtgga
    15061 aataatttta tgttagctac aaaaagttca tatcttgggg atttagtaaa aacagtaggt
    15121 gctgaaaata taactgataa cctaacagat aatgtggaat cagattatat ccaatttagt
    15181 ttagaacaaa ttttaaaaga aaatccagat tatatactta gatttgcaca tggaaatatt
    15241 gaggagacta aaaaagcatt tgatgattct tttgataaaa atcctgcatg ggctacatta
    15301 gatgcagtaa aaaatgggaa agttatagat ttagattcaa gtatatttaa tgtatctgca
    15361 aatatacatg ttaaagattc aataaataaa ttgggagata tcttgtatgg agataaataa
    15421 attttaggtg aataatatgg ataacaaaaa aattttattg atagttacag gtttgataac
    15481 tataattgtt ttgctaattc ttttttctac tataggaagt gtaaacttaa gccttagaga
    15541 aatatttgat gcactgataa atgaaaataa tccgatggtt actacgattg tatataagat
    15601 gagattacct agaaatatat tggcagcatt ggttggagca aacttggctg tttctggtct
    15661 attattacaa gctgttatga aaaatccatt agcagaccct ggaataacag ggatatcaac
    15721 tggtgcaagt gtagctgcta ttataatatt gcttctattt ccacaataca caaatatatt
    15781 accaatagtt gcctttatag gaggtcttat atcttgtgca gtagtatatt taatggcata
    15841 taaaaatggt ctaagaccag aaaggattat attagctggg gtagctgtaa acactatatt
    15901 aggtggagta atatcgtatt tatcaactat gtatagcgaa agaattcaaa gtgccatgct
    15961 gtggttaaat gggagtttgg caacaaaaac atggttagat gtaaatatgc ttatatggta
    16021 ttccatagta ggtttgatag gagcgatttt ccttattagg agtgcaaatg tactacaatt
    16081 gggagacgat gcagctacaa atctaggttt caatgtaaat aagagtagat tcataatatc
    16141 gttagtggca atatttttag ctggagtttc tacttctata gtaggggtta ttagttttgt
    16201 aggtctaatc gtaccacata taacgcgtat gttgcttggt agtgaccata aatataccat
    16261 tccatttagt ataatactag gaagcatagt tttattaatt gcagatacat tagcgagaac
    16321 aataggaggt tctatagaga ttccagtggg tgttattatg tctataatag gaggtccatt
    16381 cttcttatat ttattaagaa agagaggaag ttattaatgt tcaatgtaaa aaatattaag
    16441 ataggttatg aagataagat tatcatagac aacctaagtg taagcattaa aaaaagtgaa
    16501 atagtctcta tattaggacc aaatggttca ggaaaatcta cacttcttaa atcattgtct
    16561 agaattctga aaatcaaaca aggtgatata tacattggta aaaaaaatat gaaagttatg
    16621 agtaataaag agatttcaag acaagtggca ttattggctc aacacaatgt atcattaaaa
    16681 gatataaagg taaaagactt aatatattat gggagaatgc cacataaagg tttttttgaa
    16741 ggtaaaaaca ggaatgatga tgagatagtg acttgggcaa tgagaaatac aggtcttgaa
    16801 tcatataagg ataagttggt tagtaattta tctggaggtg aaaggcaaag agtgtggtta
    16861 gcaatggctc tttgccaaaa accagatata cttttattgg atgaaccaac gacatactta
    16921 gatatatcac atcaattaga acttatggag cttgtaagag atataaataa aaaatttaaa
    16981 atgactataa ttatggtttt acatgatata aatcaagcta gtaaatacag tgataggctt
    17041 atcattatga ataatggttc tatagtagca gatggacatc caaataaggt aataagtgaa
    17101 aaaataataa aagaagtata taaagtaaaa tgtgatatag atatagaccc aattagtaaa
    17161 aagcctagga ttcatccaat aatgctatgc agaagaacta gtagtatatg aaagtataat
    17221 attataaata attaaaaagc aaaagttatt atctatgtaa atttataagt ttgaatttat
    17281 atagataata gaagtagaaa ggaaaatata tgtatacttt agatgtatta aatagattaa
    17341 aagatataga ttgtgacaaa gatataaagt ctttatcata tgctgtattc ccaggaaccc
    17401 attgtccatt gtttggagtt gtattgactg catcatatat aagaaatatg gctcttgtag
    17461 tagtaggaac aaatgaatgt acttactata gtaaaaactt tgcatatcat aggcaatttg
    17521 gcaatgatag tgtttattca gtagtactaa aagataagga catagttttt ggtgcagaaa
    17581 aaaaagtagt agaagctgta aaatatattt cagaaattgg tgaatttgat gcaataatga
    17641 tagtaactac atgtgtacca gaattaatag gtgaagatta taatgctctg tctagtgaat
    17701 tagaagatat gcttaggata cctgttttga cagttaacac agagcattat acttgcaatt
    17761 ctcatatact tgggatgacg agagctttaa ggagtctatc atcagttatg gaaagttaca
    17821 aaaagaaaga aggagttaat atattaggtc atagacaaga aaatgtagag gatacagaac
    17881 ttgtaaaatt gctcgtaaaa aaagatataa aaataaactg tgtaattcca tctaagtgca
    17941 ctataaaaga cattaaaaat gcatctagtg ctaaattaaa catagtgaca gatatgatag
    18001 ctttggactt agcagaagat atgaaaaata agtttggtat agagtatgta tattttgata
    18061 aaaacatgaa agagtcaatt ataatagaaa attataataa actttgtaaa attttagaca
    18121 tagatataca agatgaagta tcaaagcaaa gacagagata caattcatta ttgaatgaat
    18181 gtagatatct gttggatggt aaaaaattga tttatggaaa tacaccaatg atggcatttg
    18241 aaacagtcga ttttttaact gaattaggac tggttccaga gtttatccaa gtgagagaac
    18301 tttatgaaca agataattta tttaaagata atataataaa aaaaggatat aatccatatg
    18361 taagtagaat tgcaaatata gctccactta gaagtttgta tgaaaatata aatgcagata
    18421 tttatatagg gcatgaaaat ccaatgttat taagagagaa agggcttatg caaataacat
    18481 tagatgaaca tgcacaaaaa ataggttttg agcttccaat aggaataatg aaaacattaa
    18541 ttaaattatt tgatgtagag aaatctacaa gaagggaagt gatttaatat ggaaatatat
    18601 agatattttc caaatccttc tgacagaatg ggaataatat ttatagtatc atcaataaat
    18661 gaagcatgtg ttatagaatt tggaccatca ggtacaactc attatgctat agaagcaatt
    18721 ggaagtttaa atggagaaga taaggctaaa atttattcaa cacatatgag tgaaagtgat
    18781 gttacttttg gaaattatga tagattggaa aaagctataa ttgaagtaga tagtaatatt
    18841 aaaccaaagt atatttttgt aatggcttca tctgtatctt caattatagg aacagatata
    18901 attgggatat gcaacatttt aaaggaatct gtaaactgta gactaattcc aattacaaca
    18961 ggtgggttga gagatgatta taaccaaggc gtagaagagt tcctttatat acttgcaaag
    19021 gaagtagtca aagagagtag tgaaaaattt gatagttata atattattgg atgtactata
    19081 gaccagttta attttttagc agattgcgaa gaaattaaaa gaatgatgaa agcttttttt
    19141 aaaaaagaag taaatgtaac ctttacatca tatacatcaa tagatgaaat agaaaatgct
    19201 tctaaatcaa gtctaaatat agtacttaga aaagaaggta taaaagcagc aatttttatg
    19261 aaagaaaagt atagtatacc ttatgtatat aagaaacctt atggaataaa aaatactgaa
    19321 gaatttataa atgaaataca aaaagtaact gaatgggatt tagatacaaa tacgtatgat
    19381 gatgaaatat caaatataaa aagatatata tttaatgtaa aaaggaagct ttatttttat
    19441 gaaggaagta aaaaatgtgc tgtgtttgga gattatgata ccgcattagg ctttagagac
    19501 ttattagagg agttaggtct taaaattgat taaaaaatag ctacgcacac tcgtgacttt
    19561 agtcatgagt tagtagctaa attagtcagc atatagggaa acttatatgt agagatagga
    19621 taacacctat ccaatactac ttgaattgct aaaaacccct aaagctaacc aaactaaaac
    19681 ataaggatga aataaaccta agtgtgaaag ttacgaaagt agaaaaaatt ggttagatgg
    19741 tataaggtta aaccctaagt actttaaaat gggcaatcag caggtaa
//
LOCUS       DBGJFK010000077        19563 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.077, whole genome shotgun sequence.
ACCESSION   DBGJFK010000077 DBGJFK010000000
VERSION     DBGJFK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19563
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.077"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            230..430
                     /locus_tag="ACOIAP_003001"
     CDS             230..430
                     /locus_tag="ACOIAP_003001"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639878.1"
                     /translation="MLKNYNTLVATSLNQYMDTILRIGHMGENANLNKIEHVLNVLDK
                     SLSALGFKENGTLLNLFNKYYF"
     gene            453..977
                     /locus_tag="ACOIAP_003002"
     CDS             453..977
                     /locus_tag="ACOIAP_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGZ2639879.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIV
                     WANGKNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFVVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            1077..1895
                     /locus_tag="ACOIAP_003003"
     CDS             1077..1895
                     /locus_tag="ACOIAP_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6597 domain-containing transcriptional
                     factor"
                     /protein_id="HGZ2639880.1"
                     /translation="MLSVTRYSIKNIRLKPWVKFIWFLETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKFENQDYTASNMHFNGIRDKHGFIVQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLNPTKAIEKVVLCLEEVLLSILEEDLISNKSV
                     ELLNSFIYVNRYSNIKAFCDDTNINIKTLERTCLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            1973..2284
                     /locus_tag="ACOIAP_003004"
     CDS             1973..2284
                     /locus_tag="ACOIAP_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HGZ2639881.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKSLKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(2461..3126)
                     /locus_tag="ACOIAP_003005"
     CDS             complement(2461..3126)
                     /locus_tag="ACOIAP_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639882.1"
                     /translation="MNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPHSDIDIW
                     ISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPILDLNKQHIEQICVFAIKPDCSFIELK
                     KVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLITSDNIP
                     YMAPEVVLFCKSIYIDRVGYQKDFDVTVPLLSQEQRDWLVKALITAYPDGHAWIDQLA
                     NQH"
     gene            complement(3237..3887)
                     /locus_tag="ACOIAP_003006"
     CDS             complement(3237..3887)
                     /locus_tag="ACOIAP_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2639883.1"
                     /translation="MSFLGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDG
                     LSRGAIYHHFKSKDEIIKAITSRLYNDGFYGYDVKNDEGKTALEKLQYRLLHAYEQHN
                     KQDIFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMQVKNPEIAAQMF
                     GFLLNTWCIPTVYPGNPQQMVERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(4052..6055)
                     /locus_tag="ACOIAP_003007"
     CDS             complement(4052..6055)
                     /locus_tag="ACOIAP_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGZ2639884.1"
                     /translation="MKSQKRFKILDIDIYLQPFESDIKKRMKHYEYMKSKILKNCKDF
                     SSFANAHLYYGFHKTNDGWVYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTTNGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTSFIWTDN
                     DFDLKNIISPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSVNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLSMGVPDFWIKTISNLSDENWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNPVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYIKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDI
                     VEFGGNTKKENLRDYDVYFSSTPPSSKIPIASRTAIVLLDNGI"
     gene            complement(6208..6846)
                     /gene="recX"
                     /locus_tag="ACOIAP_003008"
     CDS             complement(6208..6846)
                     /gene="recX"
                     /locus_tag="ACOIAP_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGZ2639885.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEDELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENTIDKVIDFLKS
                     YNLINDSILAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTIDEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            7122..7811
                     /gene="nadD"
                     /locus_tag="ACOIAP_003009"
     CDS             7122..7811
                     /gene="nadD"
                     /locus_tag="ACOIAP_003009"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGZ2639886.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            7812..8384
                     /gene="yqeK"
                     /locus_tag="ACOIAP_003010"
     CDS             7812..8384
                     /gene="yqeK"
                     /locus_tag="ACOIAP_003010"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGZ2639887.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDALRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            8501..8851
                     /gene="rsfS"
                     /locus_tag="ACOIAP_003011"
     CDS             8501..8851
                     /gene="rsfS"
                     /locus_tag="ACOIAP_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGZ2639888.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            9205..11625
                     /gene="leuS"
                     /locus_tag="ACOIAP_003012"
     CDS             9205..11625
                     /gene="leuS"
                     /locus_tag="ACOIAP_003012"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGZ2639889.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            11966..13027
                     /locus_tag="ACOIAP_003013"
     CDS             11966..13027
                     /locus_tag="ACOIAP_003013"
                     /inference="COORDINATES: protein motif:HMM:NF042598.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6765 family protein"
                     /protein_id="HGZ2639890.1"
                     /translation="MYQRIIFPMLKREVNIPGNLNYQYKYNGVKESKSVKTSWEFKDE
                     DKRKFRLMCLPNSKTVSAIINDLIYFHSTEEYKLQFIGMRMNVLVDIWAHMYFIGKPE
                     WYINDIKEFIAEESKYIAENKWTKSEEYRNGWHAINVSGTLDACGYESISYLGYGRMG
                     NVPDYGYLNYRYVPNWSCTDDKVKIQKNNQDNFFKAFCQMFYALKCIKNGNDFNINQY
                     DNLTAQQKTEVTKVIATRKTDQSDAWEKVIKVLGYSSLEKFDKNKWKNEFEKFSNKKK
                     INYYYFNLVAKKHIDYVNNFLEENRLKLDGMCSEYCELKVFDDTQFAKNKNRVIKIVL
                     RGDFIVDAIQLVYDGKCKT"
     gene            complement(13756..14316)
                     /locus_tag="ACOIAP_003014"
     CDS             complement(13756..14316)
                     /locus_tag="ACOIAP_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639891.1"
                     /translation="MKLRNPKIKKLLSVALLAPLVGIPIGQTANAMEISNDIPSYIEN
                     NPITIEINDSQLPKPGTVTYIDMNKLIKNLKENGIDTTIIENELYYRKAGTNKIVWTK
                     MGFDLYLSKGVALTLAGAGTGVAGILAGAIPGIGQYLAAAIVGAITMHLGSNITSGKI
                     FKFKKMRYNKGGTYVTKYYLQSVRNQ"
     gene            14754..15425
                     /locus_tag="ACOIAP_003015"
     CDS             14754..15425
                     /locus_tag="ACOIAP_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639892.1"
                     /translation="MKKYIRYQSRSELKQLRKLFEYKIDDIVGYLFCSRRTFERIERD
                     NGTSNICLANRIAELYFQRFDELFIEVDLEVIKFINSIREYTLSIEDSYIIENEIYYC
                     IFLKKLDTCRDQIWGSTYWLEDYNKYKDIRKLREANVAYLLKNTNHKITIINTENQWY
                     RIYFGLCIGKFHEILISKSCAEKCVPYILKRHVVESSLLFNNSKISDLMLLGKYDDKR
                     NILID"
     gene            15638..15814
                     /locus_tag="ACOIAP_003016"
     CDS             15638..15814
                     /locus_tag="ACOIAP_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639893.1"
                     /translation="MKTLMFVFVIMYYITIVIKSITTIVKSITRLLDSISRLKESLHK
                     LRNRPDGNQDDFNK"
     gene            16326..16406
                     /locus_tag="ACOIAP_003017"
     CDS             16326..16406
                     /locus_tag="ACOIAP_003017"
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639894.1"
                     /translation="MATMKKICLALDCNIEDIVEIKKDED"
     gene            complement(16593..17588)
                     /locus_tag="ACOIAP_003018"
     CDS             complement(16593..17588)
                     /locus_tag="ACOIAP_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGZ2639895.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTNNLDEIKDFFEKGIYC"
     gene            complement(17709..19337)
                     /gene="aspD"
                     /locus_tag="ACOIAP_003019"
     CDS             complement(17709..19337)
                     /gene="aspD"
                     /locus_tag="ACOIAP_003019"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047688 - aspartate 4-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006531 - aspartate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HGZ2639896.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAINETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFIHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKNASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT         7320 a         2496 c         2999 g         6748 t
ORIGIN      
        1 tgaagcagga accctgtgac tttagtcatg ggaggttcag aaagcacttg ataatatatt
       61 agaagaggga atagaaaatg tattaaatag acatgaaaag atagcttata gtgttagaaa
      121 atctattgag gaatatggtt tagaactatt tttagaagaa ggatattcta acacagttac
      181 agctataaaa attcctgaaa gcataggagc tttaaagctt actgattaca tgcttaaaaa
      241 ttataataca cttgttgcga catcactaaa tcaatatatg gatactattt taagaatagg
      301 tcatatggga gaaaacgcaa atctaaacaa aatagagcac gtactaaatg ttttggataa
      361 aagtttaagt gcattaggat ttaaagaaaa tggaactttg ttaaacttat ttaataagta
      421 ttatttttaa taaataaaca gggggagata gtatggaagt tacagctaag caaaaattta
      481 caacgaaaga catggtggaa acctcactat taatagcatt agtatttatt gcaactaaat
      541 ttataaatat aagattgcca atatctataa atggtgggct tgtacattta ggaactgcaa
      601 tgttgttcat atcagcaata gtatttggaa gtaaaaaagg tgctttatca ggagctattg
      661 gtatgtcact ttttgattta atatctgggt ggactttgtg ggcaccattt acctttatag
      721 ttagaggcgt tatgggttat ttacttggaa agattgtatg ggcaaatggt aagaacggga
      781 ataatttttt aatcaatgta ataggaatat gtgtttcatc aatttggatg ttatttggat
      841 attatgtaac agaagttata ctttatggta attttgtagt acctcttact tcaataccgg
      901 gtaacttaat gcaagtattg ataggtctta taatagcgct tcctatttct aaagtattaa
      961 aaaaatgtat aaaataaata taaagtgaac taaaatttac gatagcataa attatactgt
     1021 ataatattaa gatggagtac ataattaaaa aattttagta tagaggttag ttcacaatgt
     1081 tatcagttac aagatattca atcaaaaata ttcgtttaaa gccgtgggtg aagtttattt
     1141 ggtttcttga gacaaaatca aatatactgt taaataataa gttacttccg acagacagta
     1201 tagatattat tcttaatctt tctgatgtta tggaatataa atttgaaaat caagactata
     1261 ctgctagtaa tatgcatttt aatggaataa gggataaaca tggatttatt gttcaacatg
     1321 gaaatatacg tgttataggg atttcttttt atccatttgg tctatatcca tttttaaaga
     1381 taccgatttc agagtttaac agacaaattg ttgacttaga agcagtatca aaactatttg
     1441 caaagaaatt agaagagtca ttaaatccaa caaaagcaat agaaaaagtt gttttatgtt
     1501 tagaagaagt attattatcc atattagaag aagatttaat ttcaaataaa tctgtagagc
     1561 ttttaaattc atttatatat gttaatagat atagcaatat aaaagcattt tgtgatgata
     1621 caaatataaa tattaaaaca ttggaaagaa cctgtttaaa atatacaggg tatacaccta
     1681 agattttaaa gagaatttac agatttaaaa tggcaagtaa tcaacttatt tataattata
     1741 aagatgatga actttttgat tttatttatg aaaatgagta ctatgaccaa gcgcacttta
     1801 taaaagaatt taaaaaattt tcagggacgt caccaattaa atttattggt gagaataaga
     1861 cgattaaaga aaatataaag tacagctatt tataattata ctgtcgattt tttacaatac
     1921 ctccaattta ttttttgata tgatatagga aaataaattg gaggttttat atatgaaaat
     1981 tattacagaa atagttgagt ttaatgtgga agaaaatttg tcaaaagaag agtttataga
     2041 aattgtaaat gacttagaat taaaatttca ttctattcaa tccggtttta ttgatactga
     2101 gcttttatat gatgaaaagt ctcaaaagtg gattatgata caacattggg aatctataga
     2161 agacctcaag agtgcttcta gtaaaatgtt taaagattct tcaactgaga aatttagaaa
     2221 atctttaaag aatcaaactg ttaagatgaa tataatacca caaattaaaa gttggaaatt
     2281 atagaactga atgtaaaaga tagttaaata gtatcaaact aaattagcca aataacattt
     2341 tgtatttaaa ttgttatttg gcttttagtg tttattttaa tatgagtgtt atatactaga
     2401 aaaaccaaca aactgttaga gtgtggatta tcataatgtc atattcggga gctaaaaggc
     2461 ttaatgttga tttgccaatt ggtcaatcca tgcatgtcca tctggatatg ctgttattaa
     2521 agcctttaca agccaatccc tttgctcttg tgataatagt gggactgtta catcgaagtc
     2581 tttttgataa ccaactctat ctatgtatat tgatttgcaa aacaaaacca cttcgggagc
     2641 catatatgga atattatctg atgttatcag tctggcctta tccatatctc ttataattct
     2701 ttgattttgg gaaaaaagaa attttccatc tttctgtgga ttatatatca attcaataaa
     2761 atcgaactgt aactgttcgt cacactgtat attcatttta tagttatcat cctcgacttt
     2821 ttttaattca ataaatgagc aatcaggctt aatcgcgaaa acacaaattt gctctatatg
     2881 ttgcttgtta aggtcgagaa taggtcgtaa taaataatta cccaagggct catatatatc
     2941 ccatccttga ttaagcatat actgaatgct cttttcttta tctgtgtcag aaatccatat
     3001 gtcaatatca ctgtgtgggc gaatatgcat attcgcaaat aattctaggg catatccacc
     3061 acatattgaa tatgaaaagc cacaatcatt aaaaaagttt acacaatctt taattagttt
     3121 gttcatagca acctcctttt gcatgtaccg aaataaatca aatttttaaa aataccaact
     3181 aaatgtttgt tttgtgtaaa tataaaactg ccaatattaa ggcagtttta tatttactat
     3241 ttagaaaatt tattaacaaa tttttgatat tcacacatta tcttatcatt cataaaagaa
     3301 atacccataa aagcagcttg ctcaccaaac aaagtaaaac gttctaccat ctgttgtgga
     3361 ttacctggat aaactgttgg aatacaccat gtgtttagaa gaaaaccaaa catttgagca
     3421 gcaatctctg gatttttaac ttgcatagaa ttatcttgat ttccttcttc aatcaatgct
     3481 tttatccaag gcacaatatc atttataatc tcatcaaact gcgtagctaa atacttagga
     3541 ttacgcaata gtgatgatga cattaaaaaa atgtcttgtt tattgtgttg ttcataagca
     3601 tgaagcaacc tatattgtaa tttttctaat gcggtctttc cttcatcatt ttttacatca
     3661 tatccataaa atccatcatt atacaaacga cttgtgattg ccttaattat ttcgtctttt
     3721 gatttaaagt gatgataaat agcacctctt gaaaggccat ctaaattgtc tacaatatct
     3781 tgaatcgttg tctgctcata ccctttttct aagaacaact tatgtgaaat atcaagtatt
     3841 ttttgtatag tattatcagg ttcttttttt cttcccaaaa agctcactcc tcaaaacaat
     3901 catttggtat gtttatctta gcaaatacat aatgatttgt caatgtgtat ttttagcatg
     3961 ttgaacaggt atattgccat gctttcatta ttttattttt ttgccttata ctggattata
     4021 tttgcagttt cctaatattt ttggctcata tttaaatacc attatctaaa agcactattg
     4081 ctgtacgaga ggcaataggt attttagaag aaggtggagt tgagctaaag tacacatcat
     4141 aatctcttaa gttttctttt tttgtgtttc ctccaaattc tactatatca gtatttaata
     4201 tcgttttgta gtttgtattt tgaaactttg aaatatcaac tgattgtatt agattagggt
     4261 ggaaattaaa tataaataaa tatttgccct taatgtacac caaaatcttt ttatcattat
     4321 ccatatgtat aagttcatga ctattttgga taaaaatatc actgtatttt gtaagttcaa
     4381 gcatagattt atcaaaattt aataattgtt tatactttaa gttgttatct tctgaaaggc
     4441 tccattgtct tctagcatac ttatagctcc aattgttgcc ttctcgtgga aaatcaatcc
     4501 actcaggatg tccaaattca tttcccataa aatttagata cccttcacct gctagagaaa
     4561 aagttattaa tttaattaat ttaataagag atattgctct attgataaca gggttatttg
     4621 agtttatttc catattccag tacatttcct tgtcagctag ccaaaaaata attgttttat
     4681 cgccaactaa tgcctggtca tgagattcac aatatcctat atttttttct ccaggtcgtc
     4741 tagtagtaag ttcataccac attttgccta aatcccagtt ctcatcagat aagttagaga
     4801 ttgtttttat ccaaaaatca ggtactccca ttgaaagtct atagtcaaat ccaattccgc
     4861 catcttttat agggatacac ataccaggca ttccactcat atcttctgcg atacttatcg
     4921 aattaggttt aatttctttt attaattcat ttgcaaattg gagatatgtt atagcttcaa
     4981 tatctgtatt cacactaaaa tatttttcat aactatcaaa tgaaactcca agaccatggt
     5041 tatgatataa cattgaagtt acaccatcaa atctaaagcc atcaaaatgg tactcattta
     5101 accaaaattt tatatttgaa agcaaaaaat gtattacttc aggtttacca tagttaaaaa
     5161 gttttgtacc ccaagcagga tgatttccct ttgaacctga gtggaaaaat tgatgttcac
     5221 ttccatcaaa ctcatttatt ccttctaaag tattctttac agcatgagaa tgaactaaat
     5281 ctaataaaac agcaatcccc attgaatgag cagtatttat gagatttttt aagtcttcag
     5341 gagtaccaaa tctagatgag attgcataaa agtttgaaac ttggtatcca aaagatgcat
     5401 aatatggatg ttccataata gccataagct gaatggtatt gtatccagct ttttttatct
     5461 taggaagtat tttttcagta aattcattat aagttccaat agattcgctt tcagtagaca
     5521 tacctatatg acattcatat attagtggag aaattatgtt ttttaagtca aaatcattgt
     5581 cagtccatat aaatgaagtt tttggttgcc atatttgtcc attaaatcca ccaaaatctt
     5641 tttgaattac tctttttata tataatggta tacggtcaaa tgtttttcca tttgtagtaa
     5701 cttgtacctt tacctctgat ttgtgaggta agctattttg accaggaata aatatttccc
     5761 aattaccaga accaattttt cttaggggat gagattttct attccaatta ttaaagtcac
     5821 caattagtga taaactatct gcatttggag cccattccct atagacccat ccatcatttg
     5881 tcttatgaaa tccatagtaa agatgagcat ttgcaaaaga actaaaatct ttacagtttt
     5941 tcaatatttt tgatttcata tattcataat gtttcattcg cttttttata tcagattcaa
     6001 atggttgtag gtatatgtca atatctaaaa ttttaaatct tttttgactt ttcattgtat
     6061 ttctcctcca tagtaaatat tacatctaaa aaataatatt tatctcatac tatcttctct
     6121 atataattga tatatattat ataatcccaa taaaaagctt aagccaccaa tgattaattt
     6181 cataatttac ctccctagta tctatactta tatatcgtat tcatcaaaat ttaaaagttt
     6241 gtttaaaact cttttaataa tatcataatc aaagccttta taggaaagat gttgagaaat
     6301 tttttgatat attttctttt tatcttcctt cttcactctt tcataccttt tttttgctag
     6361 atacatagca ttttcaaatt cagtgtcctt atctaattca gatactgctt catcaattgt
     6421 acttctattg atacctttat tatataaatt ctgcttaatt ctgttttttc cgcatttatt
     6481 tagattaaca tttgtgttaa ctattttttg agctaatata ctgtcattta tgagattata
     6541 acttttaaga aaatctatga ccttatcaat tgtattttca tcaaattctg atgacagttt
     6601 ttcttttaat tttttttcag actggtcagc atgagataaa atatttagtg ctttattttt
     6661 agcttttata tacatttcat catctaaaat aggttttaat tcatcttcat ttatttcatt
     6721 tccttttttt aaattaaatg tataaacaag ttctttaaat atagcaataa aaaatttatc
     6781 atccacataa atattaactc tatcatcatt tcttttttgt tgttctattt ttgtaattat
     6841 acccataaat cctccttttt tatatgtaat tatattaaca aaagcaacta ataaaattta
     6901 ataaaaaact tatatttgta tgttatattt tatcaaaatt aagacaaaat agtaaaaagt
     6961 tatttttatt aaaaagtaaa gtggaatcat gttaaataat tattttttaa agcgtttttt
     7021 agcatataaa tataattata taccaaaaaa aacaaattat aagctttaag aaataaaaaa
     7081 taatggtaca atagtattat aacattaaaa ggagacaaaa tatgagaagc gaaaatctag
     7141 ttaagatggc agagttgaaa aatactgaaa aactagagaa atttaatcgc cataaaggca
     7201 aaatcaaaat aggtatattg ggaggtacat ttgaccctat acactatgct catttagcaa
     7261 cagcagaatt tattagagac aagtatgaca ttgacaaaat aatctttata ccatcaggaa
     7321 atccaccaca taaattatgt atcactacag ataagtatga tagatataat atgacacttc
     7381 tagcaactga aagcaacgaa gattttttag tttcaaaagt agaaatcgaa agaaagaaaa
     7441 ggacttatac aatagataca ttaaaatact taaagaaaaa atacaaaaat gcagacattt
     7501 attttataac aggtgcagat gcgatttgta gtgttgaaga gtggaaagat gtaaagaaaa
     7561 actttgagtt agctactttt atagcagcaa ctagaccagg aattagtttg ttaaggtcac
     7621 aagagactat agaaaaacta actaaaaagt ataatgctga cattataaca gtttatgttc
     7681 catcactgga tatatcgtcc acatatataa gggaacagct aaatgaaggc aagtcaatac
     7741 gttacttagt acccgaaaat gtagaaaatt atttatatga aaataaacta tatcaatatg
     7801 gagatgatta aatgaactta gaaaatatta accagaggct aaatcaaatg ctaccagtgg
     7861 ggaggcttag ccattcaaaa aatgttgcaa aatgtgctga aaaattatgt gagatttatg
     7921 gatgtgacaa agagaaagct tacttagcag gaatgattca tgattgtgca aagtatttaa
     7981 gtgacaagga aatagaggat tatgtaaata agtatgaaat atatttagac ccaatagagg
     8041 atggaaaccg ttccttgtct catagtgtaa ttggggcata catatgcgag tatgagtttg
     8101 aagtagaaga tgaagatatt ataaatgcaa tcaaatatca tacaacaggg agagaagata
     8161 tgtctctttt agaaaaaata atttacatag ctgatttgat tgaagaagga agaaaattcc
     8221 cagttgtaga tgcattaaga gaattagcat atggaggtaa acttgatgaa gcacttttaa
     8281 cttcttttaa taatacttta atgtttgtca tcaataaaaa agaagagata catccaagaa
     8341 cagttatggc aagaaactat ctaattaaag aaaagttatt ataaaaaacc tatataaagg
     8401 taaacatatt aataaattta aagttgacta tgttacaaaa tcgtattaat atgttacaat
     8461 aactaagtgt attttaatta ggaaagtgag gaatttttat atgacagtgg aacaaatgac
     8521 aaaaatagca tatgatgcca tagaagataa acttggtcaa gatacagtta taataaatat
     8581 aggaaaagtt tctagtttgt gtgattattt tattattact acagcatctt ctcaaagaca
     8641 ggtaaaagct attgctgaca atgtggaaga tgaattggca aaactaggat tagagccaag
     8701 aggtaaggaa ggacaaggga ctcaaacttg ggtgctcctt gattatggag acataatggt
     8761 tcatgtattt aatgaggaaa atagagggtt ttataattta gaaaaattat ggaaagatgc
     8821 accttatata gatattgaca cattagcata aacatgataa tatatgttat tataattaga
     8881 aaatttcaaa aattatatta aattgaatag actagagcag taaaagatta tattttttca
     8941 gagagttagt ggaaggtgag aactaatatt atataacttt gaacttacta gattaaaatc
     9001 tattctccat ggctggatta aaagctatct aagagggtct atgtatatag tagactaatt
     9061 agggtggtac cgcgaagatt tatcctcgtc cctaaacgta agtttagtga cgaggatttt
     9121 ttattttcaa agaattattt ggaaattata agtaaataat actaaacaag gtagttatac
     9181 acaactaaaa ataggaggta aaatatgagc gtatataatt ttaaagaagt agaatcgaaa
     9241 tggcaaaaaa tttggaaaga caataaccag tataaaatgg atactgcaca aactgaaaaa
     9301 cctaattatt atacattaga aatgttccct tatccatctg gaaaaataca catgggacat
     9361 gttagaaatt attctatagg tgatgttgtc gcaagattca aaaaaatgga aggttataat
     9421 gtacttcatc caatgggatg ggattctttt ggattaccag ctgaaaatgc agctataaaa
     9481 catggaatac atccacataa atggacaatg gaaaatatag aagaaatgaa agagcaatta
     9541 aatttattag gtattagtta cgattgggac aaagaagttg caacttcaac tccagaatac
     9601 tatagattta cacaagaaat atttttgaag tttttagagc atgggcttgc atataagaaa
     9661 aaatcatatg ttaactggtg tccttcttgt gagactgttc ttgcaaatga gcaagttgtt
     9721 caaggagcat gtgagagatg taaagcaaca gtattaaaga aagacttaga acaatggtat
     9781 tttaagacta ctgaatttgc agaagaattg cttaatgact tagatacatt agatggatgg
     9841 ccagaaaagg ttaaaacaat gcaaaaaaat tggataggta aaagtacagg agcagattta
     9901 gtttttgata tagatggaac tgataaatct atgacagtat ttacaactag accagataca
     9961 acttatggag ttacttatat ggtacttgct ccagagcatg aattagttaa agagttggtt
    10021 gcaggtactg aatatgaagc agatgttgaa gcttttgttc aaaaaatgca tactatgaca
    10081 gaaatagaaa gaacagcagc tgatgtagaa aaagaaggaa tgtttatagg tagatatgtt
    10141 ataaatcctt taaatggtaa gaaagttcct ttatggatag ctaattatgt attagttgag
    10201 tatggaacag gtgccataat ggcagttcca gcgcatgatg aaagagatag agattttgct
    10261 gaaaaataca atttagatat aattgatgta ataacagaag ataacaaaat gataaattcg
    10321 gaagagttta atggattaga tgcttcagaa ggatttgaag gaataataga taagttagaa
    10381 aaagaaggta gaggaaagag aacaattaat tatagattaa gagactggtt agtttcaaga
    10441 caaagatact ggggttgtcc tatacctgta gtttattgtg atgaatgtgg aatagttcca
    10501 gttaaaaagg aagatttgcc agttctttta ccaacagatg ttgaatttac tggaaaaggt
    10561 gaatctccac ttactacttc aaagcaattt atgtcaacaa cttgtcctca ctgtggaaaa
    10621 ccagctagaa gagaagttga tactatggat acatttgtag attcttcttg gtatttctta
    10681 agatatgtgg atagtaataa tgaaaatgaa ccatttagca aagaattagt taatagatgg
    10741 catccagtag accaatatat aggtggagta gaacatgcta taatgcactt actttatgca
    10801 agatggtttg taaaggcatt taagagtatg gggatggtag acttcaatga gccatttaaa
    10861 aacttactta ctcaaggaat ggttcttatg gatggttcta aaatgagtaa atctaaaggg
    10921 aacacagtat ctcctatgga tataatagat gagtatgggg cagatactgc aagacttttc
    10981 gtattatttg cagcaccacc agaaagagat ttagattggt cagagcaagg tgttgatgga
    11041 tgctttagat tcttaaatag agtttataga ttggttgacg agttggcaga cgtggttaaa
    11101 aaagatgtag aatttggaga attaaattct caagataaag atatgagata tactatacac
    11161 tctacactta aaaaagttac tgctgattta agtgaaaaat ttggatttaa tactgctata
    11221 tcagctctta tggaattaat aaatgatatg tataaatata aagagttaga taatataaac
    11281 gaagcagtta taaaagaagg tgtacaaact atagtaacta taattgcacc atttgcacct
    11341 catttaggtg aagaactatg gactatgata ggtaaagaag gaagtgtatt tgacatagac
    11401 tggcctaaat atgacgaaaa agctctagta aaagatgaaa tagaggttgt tgtacaagtt
    11461 aatggaaaag ttagaggaaa attaactgtt aactcaaata tatctaaaga tgagatggaa
    11521 aaggtagctt tagaagatga aaaaataaaa ggattagttg aaggtaaaac tatagttaaa
    11581 gttgttgctg tacctaagaa gttagttaat atagttgtta aataacttaa aaatataaat
    11641 ttataaaata aaggaggctg tctcaaaata gagataagcc ttttttcatt gttgaaatta
    11701 taaaaataga tttgatttca tacaagaaaa gttcctaatg aactaaaaag ttcattctga
    11761 gacaccctca ttttcatctt gaaaattatt acaattaatg ttaaatatcg tgaatacatt
    11821 gagagagtat ttgctgtgac ttctgtagat attaaagtat aagaagaaat aaaagaatat
    11881 taaagtaact agaagaatat aaagcgtagg taaaatatgt aagaattata tgctattgta
    11941 acttacaatt tatagagtgg agtttatgta tcaaagaatt atcttcccaa tgctaaaaag
    12001 ggaggtgaat atacctggaa atttaaacta tcaatataaa tataatggag ttaaagagag
    12061 taaaagtgta aaaacaagct gggaatttaa agatgaagat aagagaaagt ttaggttgat
    12121 gtgtttacca aatagtaaaa ctgtttctgc cattataaat gaccttattt attttcatag
    12181 tactgaagaa tataagttac aatttattgg aatgagaatg aatgtacttg tagatatctg
    12241 ggcacacatg tattttattg gaaaaccaga atggtatatt aatgacatta aagaatttat
    12301 agcggaagaa agtaaataca tagcggaaaa taaatggact aaatcagaag aatatcgtaa
    12361 tggttggcat gctattaatg tttctggtac tctcgatgct tgtggatatg agagcatctc
    12421 atatcttgga tatggaagaa tggggaatgt accagactat ggatatctta attacagata
    12481 tgttccaaat tggagttgta ctgatgataa agtgaagata caaaaaaata atcaagataa
    12541 tttctttaaa gcattttgcc aaatgtttta tgcattaaaa tgtattaaaa atggaaatga
    12601 ttttaatata aatcaatatg ataatctaac agctcaacaa aaaacagaag ttacaaaagt
    12661 aatagcaaca agaaaaactg accaatcaga tgcatgggaa aaagtaataa aagttttagg
    12721 atatagttct ttagaaaaat ttgataaaaa taaatggaaa aatgaatttg aaaaattttc
    12781 taataagaaa aaaataaact attattattt taatttagta gccaagaagc atatagatta
    12841 tgtaaataat tttttagaag aaaatagatt gaaactagat ggaatgtgta gtgaatattg
    12901 tgaattaaag gtttttgatg atacccaatt tgctaaaaat aaaaatagag taataaaaat
    12961 tgtacttaga ggagatttta tagttgatgc tatacagctt gtatatgatg gaaaatgtaa
    13021 aacttaacta catggagaac cttttggagg tatcatagtg gatatggatt tagatgcgga
    13081 tgattatata attaaaataa gtggctctat agggtggttt acctatacca gctagaacaa
    13141 taggtaaaat aactttttta actaaaaaag gaaaaactat agcaacagga aaagaacgag
    13201 catttaagaa atatggaaac tttactctag agccagaacc aggtaaacaa atatttgccc
    13261 ttcagggttc ctactcaata tataaattta gttcatagta tagcaaaaga tatttagatt
    13321 ctctagggat tgcttgtatg aaataattat ataaaaaaat atttaaaatt caaattagaa
    13381 gtttttgttt aatagatata ttagaaggta gcaactagtt agttgttact ttccttttta
    13441 atttaatcag tttttacagc gtttataata taacaaccaa ttcatatatt agatttactt
    13501 ttccgaataa aagtatggca gtataacaag tatctaaaat attacaaata ttaaatgaga
    13561 aaaagatggt aagttaactc caccatctta ttttttatct attaatgaat gatgctacaa
    13621 aagtcagtat aaaaaatgaa acaaacaata taatgaactt gtgtaattta cttagttgaa
    13681 acactttatt agaaacgaat aaaattaatg ctgatacaat tgcaaaaagt agatatttta
    13741 taatcatttt atcacctatt gatttcttac agattgtaag tagtatttgg ttacataagt
    13801 cccaccttta ttataacgca tttttttaaa tttaaagatt tttccagatg ttatatttga
    13861 cccaagatgc attgtaattg ctccaactat agcagcggca agatactgtc ctataccagg
    13921 aatagcacca gccaaaatac ctgcaacccc tgtaccagca ccagctaaag ttaatgcaac
    13981 tcctttagaa agatataaat caaagcccat cttagtccaa actattttat ttgttccagc
    14041 ttttctataa tataattcat tttcaataat agtagtatca ataccgtttt ccttaaggtt
    14101 tttaattagt ttattcatat ctatgtatgt aactgtgcct ggtttaggta attgagagtc
    14161 attgatttct attgttattg gattattttc tatataactt gggatgtcat ttgaaatttc
    14221 cattgcattg gctgtttgcc cgataggtat acctacaaga ggtgctaata atgctactga
    14281 taacaatttc ttaatctttg gatttcttag tttcataaaa tacctccatt ttaaattagt
    14341 tatatatcaa agatatatat tattattgta gaatatagtt attaataatt aactatatta
    14401 aatattaata aaaaatatag taaaacttaa gaatacatac aataaaactt aatataaatt
    14461 aagtctatga tataaagatg gaagtgtact atcaatatat ctttgctaaa tcaactgtta
    14521 tcaaagagag tattcttcat tttgaaaggt gattttcaaa tataagaagt aataatattt
    14581 atattcttaa aaaagtaata tatttttaaa gtttttagca acaggggacc ttttagaaaa
    14641 aagctgcaag agttgataat gctaatgttc atgtataaaa tctacaaaaa taaaatgtcg
    14701 tagtaaaaaa agaataaaac tattaaacta aaatcaggag gtgataataa aatatgaaaa
    14761 agtatataag atatcaaagt cgaagtgaac ttaaacaact tcgtaagtta tttgaatata
    14821 agattgatga tattgtagga tatttatttt gtagtagaag aacatttgaa agaatcgaga
    14881 gagataatgg aactagtaat atatgtttag ccaatagaat tgctgaattg tattttcaaa
    14941 gatttgatga actgtttatt gaggttgact tggaggttat taaatttatt aattctattc
    15001 gagaatatac tttaagtatt gaagatagtt atattataga aaatgaaata tactattgta
    15061 tttttctaaa aaaattagat acatgtagag accaaatatg gggaagtaca tattggttag
    15121 aagattataa taaatacaaa gatattcgca aattaagaga agcgaatgta gcttatttac
    15181 ttaaaaatac taatcacaaa ataacaatta taaatacaga aaatcagtgg tatagaatat
    15241 attttggctt atgtattggt aaatttcatg aaattcttat ttctaaaagt tgtgcagaga
    15301 aatgtgtgcc gtatatatta aaaagacatg tagttgaatc aagtttattg tttaataact
    15361 ctaaaatatc agaccttatg ttattaggta aatatgatga taaacgaaat attttgatag
    15421 actaaacatt acattttata aataaaacgg taatatttat tttttggaat caaggatata
    15481 aaaaatatat aaattaatta agaataaaca agaataaata tttggtaatt ataaaattat
    15541 gttataatta aaattcaaga ataatcttgc aagagactac aatctaaggg cgaaagtttt
    15601 caggtacaat caccttcgta tgaaaggggg tgagtatatg aaaacactta tgtttgtatt
    15661 tgttataatg tattatatta ctattgtaat aaaatctatt acaacaatag taaagtctat
    15721 aacaagatta ttggattcta taagtagatt aaaagaatct ttacataaac taagaaatcg
    15781 tcctgacggc aatcaagacg atttcaataa ataaatcatt acttaaatta ttttgaattt
    15841 gaaacttcgc tctaggctaa tagattgtag tttctttttt tgtttttgat actatttcat
    15901 acctttattg tatatcaaat cgtcaatgat gacaatactg acaacattga caattttata
    15961 tagttgtaaa ttatttttat atggaataaa ttaggaaaat ataatttgaa tattctaatt
    16021 tattataaaa aatatttgtt ataatattac atatgattta gtatgtaaga atttagaaaa
    16081 aaaggtgcag actatgaaaa ttagtaaatt accagaagca gaattaaaag ttataagata
    16141 tatttaggaa tcagacaagg tattaacatc aagagagatt gttgaaacta tggagcagga
    16201 tgataagaaa gtagattaaa aaaattaaat gaattagaag catattttaa gagtttggga
    16261 caatatgatt aataaaaaat atagtactat ttagtaaaaa atggagtatc aattttttgc
    16321 cacctatggc aacaatgaaa aagatatgtt tagcgttaga ctgtaacata gaggatattg
    16381 ttgagattaa aaaagatgaa gattaataag taaaaggtag ctactagtat aagtgctacc
    16441 tttttttgtg ggtaatattg tggataagtt gtgggaaact tatataaaaa ttgtggataa
    16501 aatattttac tgacataaat attggacttt gatttttaaa tgttgaaata tcaatgaaaa
    16561 aatacataaa atcataaaag atattatttt aattagcaat agattccttt ttcaaagaag
    16621 tctttgattt catcaaggtt attagttttt ccaagtgcta agataagttt tattctagct
    16681 ttttgacctg gaaggtctcc accaaatata cagccaagat tttttaaatc tctaccagaa
    16741 ccaaagtaac cataactatc gaatactcta cctgaatgac acctagaaac tataacaaca
    16801 ggaagccctt tttctctagc atattcaact ccagaaagca tttgaggagg aatattacct
    16861 ctacccattg cctcaataac tataccttta tagccactgt caacagcaaa tcttataaag
    16921 tcagcatttt ctcctacata tgctttaaat aaagcaacct tagattctac cttatcagta
    16981 tctataattg ttctatttac aatatctctt gtaaggacaa gttcattgca atcaattatt
    17041 cccaatggac cactagttag agatttaaat gtatttagag aaagagtatt tgttttagta
    17101 gcttcagaag ctaatagtac ttcattgttt aaaactacaa ggactccttt tcccatagca
    17161 tctttggata ctgcagtaca aactgatgca gataaattac ttgaaccatc atatccaagt
    17221 tcagaactac ttctcatagc acctgtgact attacaggtt tgatgttatc aattgtaagg
    17281 tctagaaaat aagctgtttc ctctaaacta tctgtaccat gcgttattac aacacctgta
    17341 atatcttttc ttgctaataa atcatttaca taatttttca attccatcat tctataaggt
    17401 gttatatgag gtcctggaat ttcatcaaag ttaaaaactt caacgtctgc aactttatca
    17461 atgttggtaa ccattgataa tatttgttcc cctgataaag ttggtatagc agctccgact
    17521 ttatcgtcta ctgtcataga tatagttcca ccagtaaaaa ctatggcaac ttttttctta
    17581 atactcatac tattctctgc ctttcataaa taaaatttat aattccgata ggattatatc
    17641 aaaaaaagta gttaaggtct acataaattc ttttattcat ataatttaga tatttcagtg
    17701 taatataatt atttcttaat tttttgccat tcaacaatat aaccatttag tatttctctt
    17761 atggcttttc ctatcttagt ataagcttca tcatatagat ttgctagaga tattctaatt
    17821 gaccattcag gaccatagaa tccatttcca ctaagtaaaa ctactgaata gtcattagct
    17881 aatttataaa gtacatctac tggagatgca tttttactta taaatttaaa taagtcttct
    17941 ccatagttta atttagccca ttcttcaata tcaaattgag tgtaatatgc agcattattt
    18001 ttattttcat taattggaag ctctaaagct tcaaataata gtttttgacg tctatggcag
    18061 atactcatat taagtttctt gtaggcatct actttatcaa tcaatgcaaa agcagagaaa
    18121 aatgccattt gtacttgttg tggagtagaa agaccagcag tatggttaag agcaacaagt
    18181 ctactatcag caacaactct ttccataaat gaaagactag aagggttaag actcatatca
    18241 ctgtaacgtt tatctactga tttttttagt tccccagtta aatcatttat tttcttatca
    18301 aaaacatttt tcttgtgaag agcaaacgta ccaagcctcc atcctgtaac tccaaagtat
    18361 tttgaataag aataaactcc aacagtgttg taaggtagct ttgacatcaa cgacgaaaaa
    18421 tcctctacaa aagttccata tacatcatct gatattatca tcaaatcttt attataattt
    18481 tcaattacat ctattagatt attacaagat gtttcatcca tagctataga agcaggatta
    18541 ttaggattaa caacgaataa agctttaatg gacttgtcac gaagtttctc taattctttt
    18601 tttgtatact gccatgtgtg agcacctttt tcgtcaactt cattagcatt tatatttaca
    18661 actttaaagt cataacgagg aaggttaggt atttcaagat aaggtgtaaa tattggagtc
    18721 attaaggcta tggtatctcc tttttttaga agttcatttg ccattaatga atcaaaaata
    18781 tagcacatag cagctgtagc accttcaaca gcaaaaattt ctacatcacc atatttacct
    18841 gatatatcat atttcatttc ttgaactagg taatcgtgta ctattttttc catatgaggt
    18901 aacattctat ctggaagtgg atagttatca ccaataattc catcagctag ttcatgaata
    18961 aactcatctc catcaaatcc aagttcattt ataccaaagt ttataatatc tctagctaaa
    19021 tatgctccag gcatatctat attttcattt ataaatttaa aaaatctttc tttaataccc
    19081 tttttttgag gcattccagc taaatgacct aaatcccaat tagaacgagt ttcattaatg
    19141 gcgaaatgac caaaagtaaa aaaggcttct ctggcagttg aacaagtcca gtttggattt
    19201 ccacgacctg catcaagtaa ttccctgtta ttttcctttg cagtatattt tgcaatatct
    19261 attaatttgt ccttaaattc aaaagggctt atttttccat atatgttttt gatttcttta
    19321 taagtatgat ttttcatgtt aaattcctcc ttatgtaata agtttcacat ttttataata
    19381 aaataaacaa gttacaaaaa tgattatact ttaattataa taggtttata gaaaaagtaa
    19441 agtatgaaat taaaataata actgtattta actttattaa atatatatta aaacaaaaaa
    19501 tgctttttaa taaaaaatga ttgttatata aaataaatct tcaatttaat tatcagctta
    19561 gtt
//
LOCUS       DBGJFK010000078        19410 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.078, whole genome shotgun sequence.
ACCESSION   DBGJFK010000078 DBGJFK010000000
VERSION     DBGJFK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.078"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            339..1352
                     /gene="aroF"
                     /locus_tag="ACOIAP_003020"
     CDS             339..1352
                     /gene="aroF"
                     /locus_tag="ACOIAP_003020"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGZ2639897.1"
                     /translation="MIVVLKIGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKIVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEEQIVSIAEDVKKSGAGFLRGGAFKPRTSPYAFQGLRYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            1374..2438
                     /gene="aroB"
                     /locus_tag="ACOIAP_003021"
     CDS             1374..2438
                     /gene="aroB"
                     /locus_tag="ACOIAP_003021"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGZ2639898.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILNNVGEEIKRIYFGNKIFIVTD
                     ENVAKLYLDKLKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGINFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKHYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVEAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            2438..3751
                     /gene="aroA"
                     /locus_tag="ACOIAP_003022"
     CDS             2438..3751
                     /gene="aroA"
                     /locus_tag="ACOIAP_003022"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGZ2639899.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSIAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFNRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTMKDFGIEI
                     INNNYKEFIIKGSQTYKARDYKVEGDYSQGAFYLSADAIGEDINILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNSTLIDASQCPDIIPVLSVVAALSRGKTTIIN
                     AGRLRIKECDRLHAINIELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFEMLGGRIDEWNMGK"
     gene            3729..4808
                     /gene="aroC"
                     /locus_tag="ACOIAP_003023"
     CDS             3729..4808
                     /gene="aroC"
                     /locus_tag="ACOIAP_003023"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGZ2639900.1"
                     /translation="MSGIWGNNLKISIFGESHGNAIGINIDGLPSGVELDLEKIDREM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEVGAHIKKIK
                     NIEDMSFNYVNISKQQLSNLQTLELPLLDLSKEEKMKNTIIDAKNQRDSVGGIIECAV
                     VGVNVGFGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKEKKDDILSIKGRHDP
                     CIVQRVIPVIEAVTAIGIFDLMKGR"
     gene            4811..6007
                     /gene="pheA"
                     /locus_tag="ACOIAP_003024"
     CDS             4811..6007
                     /gene="pheA"
                     /locus_tag="ACOIAP_003024"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGZ2639901.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETIQFFNSIMEISRGLQKRLMDNDSEQKIEFRLDS
                     SKKKFDLSSVNKYKSLKEELNKKNILVGFPGKSGSFTEEALNKFFNKKTAKKQFKEFE
                     DVFIALKNKKIDYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLKDIKEIYSHPQGIGQCSEFLKQNSAWKLIPFNNTATSAELVKKLQDKTKAAIASKK
                     AASIYGLEIISPCINDITNNYTRFVVISNQIHIEEESNKMSVVFSVEHKAGKLYKVLG
                     YFAENNINMTKIESRPMKNTSWRYFFYIDFECSIYNSKVYNLLELIELNTAYFKFMGV
                     YKNKTK"
     gene            6047..6856
                     /gene="aroE"
                     /locus_tag="ACOIAP_003025"
     CDS             6047..6856
                     /gene="aroE"
                     /locus_tag="ACOIAP_003025"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGZ2639902.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDVS
                     KLASAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLREDMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAAITYLLDSGIEKVYVSTRKKDDKKLLNS
                     KAILVDYEELKCITGDIILNATPVGMYPNVGISPVSKSIIQNFDTLVDLIYNPGETEF
                     LRIGNSIGKKTCDGLYMLVGQAIKSQEIWQNAKIDNSILDVIYNELKLEFL"
     gene            6868..7401
                     /locus_tag="ACOIAP_003026"
     CDS             6868..7401
                     /locus_tag="ACOIAP_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGZ2639903.1"
                     /translation="MTNKTKEKLILIGMPGSGKTTIGKLLAREYNCSFCDMDDYIVKI
                     AQKSIAELFSEGEDIFRNYETQACRELSISNKAVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNTAVY
                     NIINAVSEKFKFEFKEK"
     gene            7422..8261
                     /locus_tag="ACOIAP_003027"
     CDS             7422..8261
                     /locus_tag="ACOIAP_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGZ2639904.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKRGIDFASEQVFNGANYIITPTGRNNIRNLELVENLI
                     LKLGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEDRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLIKEAIFNNDKSKLIEYFKKSSIRREI
                     LEK"
     gene            8630..10009
                     /locus_tag="ACOIAP_003028"
     CDS             8630..10009
                     /locus_tag="ACOIAP_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HGZ2639905.1"
                     /translation="MLEYETNNLMTITITGWIILSFLFLGIIIYILYSKAKSQKTIEK
                     VAYTDFVTGYSNWRKFELDVTNLLKKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLI
                     LKDIADTLNELININETFARVSADNFNILLTYNKKEDIINIIKKIMVNNELVNLSFGI
                     YEIKDKALSVSVYSDRASLAKSSIKNNSDVNFAFFNDELREKLLLEDKIEKEMEYALE
                     SGQFVMYLQPKYNIKLNKFCGSEALVRWQYTEKEVIYPGDFIPVFEKNRFIRKIDMYI
                     LEQACKEIRSLFDKGISPLPISVNFSRVDFLKKDFISNIVNVCDRYKIPYGLIEIEIT
                     ESSMFGDTDILFNVSRNLQDIGFIVAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDD
                     KDVDKSQIVIKSIVSLIKQLGIRVVAEGIETKSQIEMLKKANCDIVQGYYFSKPLPIK
                     EFEKLVYKI"
     gene            10042..13479
                     /locus_tag="ACOIAP_003029"
     CDS             10042..13479
                     /locus_tag="ACOIAP_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HGZ2639906.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSMANMVSYFNTIDNSKIIPLLANISKESDFQRISIV
                     SPDGISHTSDGKIIDVSNYQYFKKAISGESNISEVVKSPIDGKDTFVIATPIFNKNNK
                     IIGILYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYKDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIILIIYIIYKNNKSQRDILKANKEISSITNSIPGG
                     VQKCTLGETCKINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEISKQL
                     YKNKTIELEYRIITKSGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENILGGILITELNEDFTIKYTNSGYLSMIGYTREQLENELKYKACDLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITENV
                     PYSLVESGVIHKDFSNDFINMYEKVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNENW
                     QKPFGIKPDNNYSQMAKTIANSIVHKENKEVFLNTFLCENLLDAYKNNITEIKLEYQR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEKASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKHLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENAKKKAEKICDIFRNSYTKNKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKVANK
                     CEKSNPVLKEVLDSIDNYIYIVNPNTYELLFVNNKVSRSGLEIKLGQTCYKSLLKSDR
                     PCSNCPLNGLEENKHSKFKIETNTFGTNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            13496..14242
                     /locus_tag="ACOIAP_003030"
     CDS             13496..14242
                     /locus_tag="ACOIAP_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HGZ2639907.1"
                     /translation="MLNGITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIILIIYQ
                     IFKKKIKEKKVFYRVLKIIISVFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TIPSTTLKGRLNTALKYLKVNDNCYVVVSGGKGSGENITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKFKIEERSERKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIFFDR"
     gene            15122..19288
                     /locus_tag="ACOIAP_003031"
     CDS             15122..19288
                     /locus_tag="ACOIAP_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdrD B-like domain-containing protein"
                     /protein_id="HGZ2639908.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANVPVVLQDIATGVRLTVL
                     TNASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFAAAIVGPVPIAEIPPISSVINPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIQNILDSCVSVSNINLIIDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNFLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEIGTVINSQNNNQLTVEFFS
                     EGESVIGNDYAIDDVSLREITVPTFTPIKTSNTETANIGDIVTYTVTLDNTCNSPLTN
                     VFFRDIIPNGLKFIPGTVTVDGISVPGVDPNIGFQLPDIGGGTRIEVTFNVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNNFSVDSNPVPVEVISADIEVTKLSEPSIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPDSIINSEYSLDGGVSFQPWNGSLNIGTLELGATR
                     VIIIRGIVNPTTVGIIRNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVANLGPANAENVILNDDIPDVILNPEYSLDGGVSFQPWNGSLNIGA
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVANEDVAVPGEEFVYTIEIFNEGPSNAMNVVLTDNIPDVILNPEYSLDGGASFQPWN
                     GSLNIGTVAPGQLIRIIIRGLVSSTATGNITNTAEVSAEVPEPVTDSSTVITPVVASA
                     DIEVIKTSNMDTAVPGEIFSYTITVTNLGPSAAQSIVLTDDIPDIILNPEYSLDGGVS
                     FQPWNGNLNIGTLDTGEIRSIIIRGTINQTSVGTIINTATVSSTTPDPNPDNNTSTVE
                     TDISPLADISVIKGNEPLAIQGERFIYGIEIVNAGPSFSENIVLTDNIPASILNPEYS
                     IDNGVTFQPWTGSLNIGTLDAGEIRNVIIRGTVSQTAVGTIINTATVSSTTPDPNLNN
                     NTSTSEAEVSSSADISVVKRSNQNVVVPGDVLNYTIEVRNAGPSTAQNVTLTDNISAS
                     ILSPEYSIDNGVTFQPWTGSLSIGTLYAGEIRNIIIRGIASETAIGTIINTATVSSTT
                     PDPNPNNNTSTSEIDISSSADISIIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKTVFSLDRGVSFQPWTGSINIGILPAGTLRVILLRGLIKSTCLDKLTNI
                     AEVTSTTPDSDLNNNISRVQVEIKQCCSNDCCCNCCCNNCCNCFFNDCCNDCGYKDCC
                     CNCCKNDFWC"
BASE COUNT         7902 a         2139 c         3264 g         6105 t
ORIGIN      
        1 ttataattag taaacaagaa gaataataaa ttataaaaat ggaggataat actatgaaag
       61 ggatactaaa agaactagca gcaaaacttt atagcttttt ttactttatg ttctggggct
      121 tttattttag cgctggctat ttcttttaca aaaatatatg taattccttt ctggtgaggc
      181 cttattttag taattttgag cataagtaaa ttttataaaa atgattattt tatatattta
      241 tgtaagattt aatgcttgat agattatttt agagaactca ttagtgagtt ctctttttta
      301 ttttaaatat aaaattataa tattgggagg tagtaaaaat gatagtagta ttaaaaatag
      361 gagcagataa aaatgaagtt aaaaaattaa ttgaggctat tgggagagaa ggagtagaag
      421 ttaatcccat agatgggaca gaattaactg ttttaggttt agttggagat actagtaaaa
      481 tagatgccaa aagaatagaa gcaaataaga tagttgaaaa agttatgcat gtagtagagc
      541 cttttaaaaa ggccaataga aaatttcatc cagaaccttc tataataaat gttaatggaa
      601 tggaaattgg ttcgaaaaaa attgctatga tagctggacc ttgttctgtt gaaacagaag
      661 agcaaatagt atctatagct gaggatgtga aaaaatcagg tgcaggattt ttgagaggtg
      721 gagcattcaa accaagaaca tcaccatacg ctttccaagg attgagatat gatggattgg
      781 acttattaaa gaaagcaaaa gaaaaaacag ggcttcctat agttacagaa ataatgtcaa
      841 cacaagatat agatatattt gaagaaaatg tagatgtaat tcaagttgga gctagaaata
      901 tgcaaaactt tgatttatta aaagaattgg gtaaaacaaa taaaacaata cttttaaaaa
      961 gaggattatc tgctacaatt gaagagtggt taatgtcagc agagtatata atggctggag
     1021 gaaatgaaaa tgtagttctt tgtgaaagag gtataagaac ttttgaaaca tacactagaa
     1081 atactttgga tttaagtgca attttagctg tgaagaaact tagtcatttg ccagttatag
     1141 ttgatccaag tcatgcagca ggcaaatcat ggatggttga ctctttatct aaggcagcaa
     1201 ttgcagttgg agcagatggt ctgataatag aagttcataa tgacccagca catgcacttt
     1261 gtgatggaaa acaatcaatt aaaccaaatg aatatgatga attaataagt gaattaaaga
     1321 ctattgcatc agcagtagga agagaaatat aatctataaa aggatggtta aacgtggaag
     1381 aaaaactatt agtaaattta aaagaaaata gctacaatat atttattaaa aaaaatatac
     1441 taaacaatgt aggagaggaa ataaaaagaa tatattttgg aaataagatt tttattgtaa
     1501 ctgatgaaaa tgtagcaaaa ttatacctgg ataaattaaa aaataattta agtgaatctg
     1561 gatttgaaat aaaatcttta atattaaaat ctggtgaaga aacaaagtca tttaatactc
     1621 ttcctaaaat atacgatagt ttacttgact ttaagttaac tagaaaagat ttgattatta
     1681 ctttaggagg aggggtaata ggtgatttag gtggatttgc agcagcaact tttttaagag
     1741 gtataaattt tattcaaatt ccaacatctt tattagcaca agttgatagt tctgtaggtg
     1801 gaaaagttgg agttgacctt gagagaggta aaaatttagt aggaagcttt tatcaaccaa
     1861 aagctgtatt tattgaccca aatgtattat tatcacttcc agaaaaattc tatagagatg
     1921 gaatggcaga agttataaaa tatggatgta taaaagataa aacttttttt aataaacttt
     1981 taagtttaaa aaatagagaa gaagtaatgc aacatataga atacattata cataaatgtt
     2041 gctttattaa aaaaactgta gttgaagctg atgaaaaaga ttttggggat agaatgcttt
     2101 taaactttgg tcatacatta ggtcatgcta ttgagaaaca ctacaatttt acaggttata
     2161 ctcatggaga agctgttgcc ataggaatgt ataagataac tttagaaagt gaaaagatag
     2221 gaattacaaa aaaaggtaca tcagaactta taaaatcaat tttaatgaat tataatttgc
     2281 cttatgagat tgaactaaga gataataaat ctatagtaga agctatatct cttgataaaa
     2341 aaaatctagg tgatacatta aaaataatac ttttaaaaga tattggagag agtattatat
     2401 ataatactac ttctaaattt tttcaggagg taagataatg ggaagtctaa aaatatatcc
     2461 aagtaaatta tctggagatg taaaaatacc accatcaaaa agtattgcgc atagggcagt
     2521 tatttgttca tctctaagca atggaaaaag tagaatttct aatatagatt tttctgatga
     2581 tataatagct actataagag caatgacatc attaggagct attatagaaa agaaagaaga
     2641 tattttagaa atttcaggaa ttttttcgaa ggaaggtatt ttaaatagag agaatcagtt
     2701 gaatcaacct aaattgacaa tagattgtaa tgaatcaggc tctacattga gatttttagt
     2761 acctatatct ttagcatttg atggtgtaaa aaggtttata ggtagaggta atcttgggaa
     2821 aaggccactt gatacttatt atgagatatt taacagacag aatataaaat atagttacaa
     2881 agaaaatcag ttagatttga ttatatcagg taagcttaaa ccagatgagt ttagagtaaa
     2941 aggaaatata agttctcagt ttatcacagg tctattattt atattgccta cattagaaag
     3001 tgattcaaag ataataatta ctactgagtt agaatctaaa ggatatttag atttaactct
     3061 ttcaactatg aaagattttg ggatagaaat tataaacaat aattataaag aatttattat
     3121 aaaaggaagt caaacgtata aagcgagaga ttataaagta gaaggagatt attctcaagg
     3181 agcattttat ttatcagcag atgctatagg agaagatatt aatatattgg accttaaaga
     3241 agattctctt caaggagata gtgaagtagt tgaaatttta tctaggatgg gaatggaaat
     3301 attaagagag ggtaacaaaa taaaaggaat aacaaatggt ttaaatagta ctttgataga
     3361 tgcatctcaa tgcccagata taatacctgt attatctgta gtagcagctt taagtagagg
     3421 gaaaactaca ataatcaatg ctggtagact tagaattaaa gaatgtgata gacttcatgc
     3481 aataaatatt gagttaagta aacttggagc gaatatagag gagaaagagg atagtttgat
     3541 aatcgaagga gtaagtaagt taaatggggg agtagaggtg tggagtcaca aagaccatag
     3601 aattgctatg acacttgcaa ttgcttcttg tagatgtgat aaaccaataa tactaaaaga
     3661 ttttgagtgt gtatcaaaat cttatccaca tttttttaaa gattttgaga tgttaggagg
     3721 acgaattgat gagtggaata tggggaaata atttaaaaat atccattttt ggagaatctc
     3781 atggaaatgc tataggtata aatatagatg gtcttccttc aggagtggaa cttgaccttg
     3841 agaagattga tagagaaatg aagagaagag cacctggaaa aaattctata tctacttcaa
     3901 gaaatgaaag tgatatacca gaaattctaa gtggatattt taatggaaga actacaggaa
     3961 cgccattatg tgcaatcata agaaatagtg atactcgttc aaaagattat ggagaactta
     4021 aaaatctaat gagaccagga catgcagatt tcacaggaaa tgtgagatac tctggattta
     4081 atgactacag aggtggaggt catttttcag gtaggataac agctccatta gtattttgtg
     4141 gggctatatg taaacaaatt ttgtcacaaa aaggaataga ggtaggagca cacataaaaa
     4201 aaattaaaaa tatagaagat atgagtttta attatgtaaa tatttcaaaa caacagttat
     4261 caaatttgca aactttagaa ttacctttac ttgatttatc aaaggaagaa aaaatgaaaa
     4321 atactattat agatgcaaaa aatcaaagag attcagttgg tggtataatt gagtgtgcag
     4381 tagtaggtgt taatgtaggg tttggaaatc cattttttga ttctgttgaa tctactttat
     4441 cacatttatt gttttctgtt cctgctgtaa aaggcgtaga gtttggttta ggttttgaac
     4501 ttgcagatat gtatggttct caaagtaatg atgaaatgta ttatgaagga aatcaagtta
     4561 aaagcaaaac aaataataat ggaggaatta ttggaggtat tacgactgga atgccaataa
     4621 ttttcaaggt agcaatcaag ccaactccat caattagtag acaacaaaac acagttaata
     4681 taaaagagaa aaaggacgat attttatcta ttaaaggcag acatgaccct tgtatagttc
     4741 aaagggttat acctgtaata gaagcagtaa cggccattgg aatttttgat ttgatgaaag
     4801 gacgataata atggaggatt taacgagata tagaaatgag attgacaata tagataaaga
     4861 gcttattcaa ttatttgaaa agagaatgaa tacagttctt gaaattgcca gacataaaat
     4921 gaaaaataac actactatac ttcaaaaaga tagagaagaa aaagtactaa gtagagccgt
     4981 agataattta gacaataaag cctattcaca agaaacaata caatttttta attctataat
     5041 ggaaattagt agaggattac aaaaaaggtt gatggataat gatagtgagc agaaaattga
     5101 atttaggcta gactcatcaa agaagaaatt tgacttgtca agtgtaaata aatataagtc
     5161 tttaaaagaa gaattaaata aaaaaaatat cctagtaggt tttcctggaa aatcaggttc
     5221 atttacagaa gaagcactaa ataaattctt caacaaaaaa acagcaaaaa aacaatttaa
     5281 agaatttgaa gatgttttca tagcacttaa aaataaaaaa atagactatg gaataattcc
     5341 catagaaaat tcatccactg gtgctatctc tgaaacttat gaccttttaa gaaaatacgg
     5401 tttttatata gttggagaag aatgcataaa aatagaccaa aatttaattg ggataaaaga
     5461 tacaaaactt aaagatataa aagaaatata ttctcaccca caaggtatag gacaatgtag
     5521 tgaattttta aaacaaaata gtgcatggaa gttaatacca tttaataaca cagcaacaag
     5581 tgctgaactt gtaaaaaaac ttcaagataa aacaaaagca gcaattgcaa gtaaaaaagc
     5641 tgcaagtatt tatggattag aaataataag tccttgtata aatgatatta caaacaacta
     5701 tacaagattt gtagtaatca gtaatcaaat acacattgaa gaagagtcaa acaaaatgag
     5761 tgtagtgttt tctgttgaac ataaagcagg aaagctttat aaagtacttg gatactttgc
     5821 tgaaaataat ataaacatga caaaaataga atcaagacct atgaaaaata cctcatggag
     5881 atatttcttt tatatagatt tcgaatgttc tatatacaat tctaaagtat acaatttgtt
     5941 agaattgata gaacttaata cagcgtattt taaatttatg ggagtatata aaaataaaac
     6001 taaatagata agataaattt ttatttaatt attaggaggt gtaaatatga atttttttgg
     6061 tttagtaggt gaaaaactct ctcatagtgt ttcccctcaa atccacaaga gagtattcga
     6121 aatattgaat attgaaagtg cctataaaaa ctttgaaatt tcaaaagaag atgtatctaa
     6181 gctagctagt gctataaaat tattaggaat acaaggagta aatgttactg taccatataa
     6241 agaacgtatt atgaaatatc ttgattttat atcaccagag gcaaagcgta taggagcagt
     6301 taatacaatt ttactcagag aagatatgtt atatggttat aatacagatt actttggtct
     6361 tgatagtatg tttaaaatgg ctaatattga tgttcaagga aaagtggcag ttatattagg
     6421 aactggtggt gcttctaaag ctgctattac atatcttctc gattctggaa tagagaaggt
     6481 ttatgtttca actagaaaaa aagatgataa aaaattatta aatagtaaag ctatattggt
     6541 agattatgaa gaacttaaat gtataacagg agatataata ttaaatgcta caccagtagg
     6601 tatgtaccct aatgtaggaa tttcaccagt gtcaaaatct attatacaaa attttgatac
     6661 attagtagat ttaatctaca atcctggaga aacagagttt ttaagaattg gtaatagtat
     6721 tggtaaaaaa acttgtgacg gtttatatat gttggtaggg caagcgataa aatctcagga
     6781 aatttggcaa aatgctaaaa tagataatag tattttagat gttatatata atgaattaaa
     6841 attagaattt ttgtaaggga gattgtcatg acaaataaaa caaaagaaaa attaatatta
     6901 ataggtatgc caggtagtgg aaagactaca attggaaaac ttttggctag agaatataat
     6961 tgtagttttt gtgatatgga tgattatata gttaaaatag cccaaaaaag tatagcagag
     7021 ttgttttcag aaggagaaga tatttttaga aactatgaaa ctcaagcatg tagggaactt
     7081 tctataagta ataaagcagt gatatctaca ggtggaggtg taataaaaaa ggatgtcaat
     7141 atggaaatat taaaagaaac aggtataata atttttattg atagacctat acaaaagatt
     7201 ttagaagata taaatattaa ttcaagaccg ttattaaaaa acggaaaaga tagattgtat
     7261 aatctttata atgagagaat aaatctatat aaaaaatttt cagatataga gattttaaat
     7321 gacaaatcat taaatactgc tgtatataat attataaatg cagttagtga aaaatttaaa
     7381 tttgaattta aagaaaaata atctaggagg aaataaaaat aatgaatatt gttattgtag
     7441 gattaggagt tataggaggt tcttttgcta aagcattaaa aaaagctgga tatgaaaatg
     7501 tatttggagt agatgtagat ttagaaactt taaaaaaagc agaaaaagca aaaatcataa
     7561 aaaaaggatg tactacaggt aaagagttat ttaaaaaagc tgatttaatt atactatcta
     7621 tatatcctag attagttgta gattttctaa ataataataa aaactttttt aaaaaaggaa
     7681 ctataattac tgatactaca ggaataaaag aaacacttat caatgatgtg ttgcaaatta
     7741 ttccagatga tatagatttt atatttggcc atccaatggc aggcagagaa aaaaggggaa
     7801 ttgattttgc aagtgaacaa gtttttaatg gcgcaaatta cataattact ccaactggca
     7861 gaaacaacat aaggaattta gagttagttg aaaatttaat tttaaaactt ggatttaaaa
     7921 gagtaaaaaa gttaacttca caaaaacatg atgagattat agcttttact tctcagttac
     7981 ctcatgttat ggcagttgct cttataaata gtgatgaaga agatagagat acaggtaaat
     8041 ttattggaga tagttataga gatttaacta gaattgcaaa tatgaatgaa gacttatgga
     8101 gtgaactttt tctagggaat agagataatt tactaaaagt tatagaaaac tttgaatcag
     8161 aagtaaactt aataaaagaa gctatattta acaatgataa aagtaaattg atagagtatt
     8221 ttaaaaaatc atcaataagg agagaaattt tagaaaaata aatattgata tttaagctgt
     8281 atatagatgg gtataaatat aagcgatagt gtatttaatt gtattaataa atatggattc
     8341 aatataatta aatatgctat tgatatattt gtacccttaa atattgttat cttttaaatg
     8401 ataatgacat ttacctaaat actctttatt aacaatttat aaaacttaat tgtaaaaaat
     8461 acttattaat agtaaaataa agtgaatcaa ttatattata attgctaaag agggtgaggt
     8521 gtagctattt gaaaaaaata tattaatagt aaggaatgta tcaatagcat ttatagtact
     8581 attctttttt agtgtatttg cattctttta tgtagccaat attaataggg tgttagaata
     8641 tgaaacaaat aacttaatga caattacaat tactggatgg attatacttt cttttttatt
     8701 tttaggtatt ataatttaca tattatattc aaaagcaaag agtcaaaaaa ctatagaaaa
     8761 agtagcatat acggattttg taacaggtta ttccaactgg agaaagtttg aattggatgt
     8821 tacaaattta ttaaagaaaa catcgcaaaa taataaatat gcaatggtca tatttgatat
     8881 tgataaattt aaagcaatta atgatatata tggccataaa aagggaaatt taatattaaa
     8941 agatattgca gatactttaa atgaattgat taatatcaat gaaacttttg ctcgtgtaag
     9001 tgctgataat tttaacatat tattaacata taataaaaaa gaggatataa taaatattat
     9061 caaaaagatt atggtaaata atgaacttgt aaacttatct tttggaattt atgaaattaa
     9121 agataaggct ctatctgtaa gtgtatatag tgacagagcc tcacttgcaa aatcatcaat
     9181 aaaaaataat agtgatgtaa actttgcctt ttttaatgat gaattaagag agaaattatt
     9241 acttgaagat aagatagaaa aagaaatgga atatgctctt gaaagtgggc agtttgtaat
     9301 gtatttacaa ccaaaatata atattaaatt aaataaattt tgtggaagtg aagctctagt
     9361 cagatggcaa tatacagaaa aagaagtcat atatccaggt gattttattc ctgtatttga
     9421 aaaaaatagg tttattagaa agattgatat gtacatatta gaacaagctt gtaaagaaat
     9481 ccggtcttta tttgataaag gaatttcacc tttacctata tctgtaaact tttcaagagt
     9541 tgatttttta aaaaaagatt ttatttcaaa catagtaaat gtatgtgata gatataaaat
     9601 accatatggt ttaatagaaa ttgaaattac tgaatctagc atgtttggag atactgatat
     9661 tctatttaat gtgagtagga atctacaaga tattggcttt atagttgcaa tggatgattt
     9721 tggttcagga tattcttctg taaatatgct taaaaatata ccattaaatg taataaaatt
     9781 agatagagga ttttttgttg atgataaaga tgttgacaag agtcaaattg ttataaaaag
     9841 catagtttct ctcattaagc aattaggaat aagggttgtt gctgaaggaa tcgaaacaaa
     9901 aagtcaaata gaaatgttaa aaaaagcaaa ttgtgatatt gttcaaggat attatttttc
     9961 aaaaccatta ccaattaaag aatttgaaaa attagtctat aagatatagt cagcgagtct
    10021 taaatgggag gtggtgatta agtgataaga gcaaaatcgt taaaaaatgt actgagtatt
    10081 gttttaatat ttttatttac aataatttct ttttctgatt ttgcatttaa aactaatgtc
    10141 caagaagaag aaaatagtaa aattaattta agggaaatat ccttacaaag ttccaatgct
    10201 ataaaaataa aactagacag ttctttgtcc tttattaaaa gcatggcaaa tatggtttcg
    10261 tattttaata ctatagataa ctcaaaaata attccattat tagctaatat atcaaaagaa
    10321 tctgattttc aaagaatttc tattgtatct cctgatggaa taagccatac cagcgatggc
    10381 aaaattattg atgtttcaaa ttatcaatat tttaagaaag ctattagtgg agaaagtaat
    10441 atatctgaag ttgtaaaatc tccaattgat ggaaaggata cttttgttat agctactcct
    10501 atatttaata agaataacaa aataattggt attttatatg gttcttacta caatgataaa
    10561 ttagctgaat ttatagatat aacaagtttt aatagtgaag ggtacataga tatatttgaa
    10621 tctagtggac aatttgttct aaaatcttca catacaaaca agttgattaa gtcaagtagt
    10681 aatatatatg atatatttaa aaaagcttct tttgatgatg gttatagcta taaaaaaata
    10741 tataaagata caaaaaataa caagagtggc tttacgtcat atgaatataa aggagaaaat
    10801 cgctatgcta cttatacacc aattggtgta aatgattggt atgtaatttc tgtgatacca
    10861 caatatactg taaggagaaa cattgataaa ataaatcaat tagcattttc tcttattttc
    10921 aaggtattct tgttatttat tatacttata atatatatta tttataagaa taataaatct
    10981 cagagagata tactaaaagc taacaaagaa atctcatcta ttacaaatag cattcctgga
    11041 ggagtacaaa aatgtacctt gggtgaaaca tgcaaaatca attttttaag tgatggattt
    11101 atagagttgt tcggttatac aagagaagaa ataaaaacat tgtttaataa cgatttttat
    11161 agtttaatac ataaagatga tgttgaaaga ataaaaaaag aaatttctaa acaactttac
    11221 aaaaataaaa ctattgaatt agaatataga attataacaa aaagcggtaa tacagtatgg
    11281 gttttagata agggagagct tataacagaa cctgatggaa aagaatattt ttgttgtgta
    11341 actgtagata ttactagaac aaaacaatta gaacaagaga tggaacaaaa aaatctagaa
    11401 cttgaaatga tatcagaaaa tattttaggt ggtatactta taacagaact taatgaagat
    11461 tttactataa aatacactaa ctctggttat ctttcaatga ttggatatac acgtgaacaa
    11521 ttagaaaatg aacttaaata taaagcatgt gaccttgttt tttatgagga tagaaagaag
    11581 gctctggaaa gtatacaaca tcaattaaat acaaaaggaa tagctgtata tcaacataga
    11641 ataagaagaa gagatggtaa tattatctgg gtttctataa aaggaaggct tattattgat
    11701 gatgatggta ttgaaaaagg tatttggatt ctaaatgata taacagattt aaaaaatgca
    11761 gaacaaaaac ttaaaataaa tgaagaaaga tttagaattg cattaaaaca aacatcaaac
    11821 actatatttg agtatgatat aaaaaccaag tcacttttaa atactagcaa agagcttgat
    11881 aagtataata tttataaaat cactgaaaat gttccgtatt ctttagtaga atcaggagtt
    11941 attcataaag attttagtaa tgattttata aatatgtatg aaaaagtaat aaatggagca
    12001 aaaaaagcaa gttgtgtagt taagatgaaa cttccagatg aaaattatat atggaataaa
    12061 gttactctaa ctactatttt tgatgaagat ggtaatcctg taagagcaat tggtatacag
    12121 gaagatataa gcaaacaaaa agaagcagag ataagataca atcaagaagg gaagtatcat
    12181 tcagctatat tgtcggaagc aatgataact tatgaaataa atgtatcaaa ggatactttt
    12241 atcaaaggca atgaaaattg gcaaaaacca tttggaatta aaccagacaa taactattct
    12301 caaatggcaa aaacgatagc aaatagcatt gtacataagg agaataaaga agtattttta
    12361 aatacatttt tatgtgaaaa tttattagac gcatataaaa ataatataac tgaaataaaa
    12421 ttagaatatc aaagaatgaa tcaagaaaat aaaatgattt gggtcatttg cacaatgcac
    12481 ttaataaaag attctattac gaatgatata aaagcacttg cttatgttaa agatatcgac
    12541 aaacaaaaaa atgaagaaat tagattaaaa ttaaaagctg aaagagatac tcttacagga
    12601 ttatataata aaggtactac agaaaaattg attaatgatt tcttaaactc tgagaaagca
    12661 agcttaggaa tgcatgcatt tttaattgtc gatatagata attttaaatc tgtgaatgat
    12721 aatttaggtc atgtatttgg agataaagta ttatttgaag tttctaaaca cctaaaacct
    12781 atatttagaa aagatgatat agtaggtcga attggtggag acgaatttat agtattctta
    12841 aaaaatattc aatcttttga gaatgccaaa aagaaagcag aaaaaatatg cgatatattt
    12901 agaaattctt atacgaaaaa taaaaagaca tataaaatat ctggaacagt tggaatttca
    12961 tttgtaccag aacatggaac tgtatttgaa gaactttata aaaaagcaga catagcactt
    13021 tattatgcaa agagcaaagg aaaagataag tatgcacttt ataatgattg catctaccaa
    13081 aatgaacttg aaaataatat aagtgacaat aatataaaag tagcaaataa atgtgaaaaa
    13141 tccaatccag tgcttaaaga agttcttgat tctattgata attatatata tatagtgaat
    13201 ccaaatactt atgaacttct ttttgtcaat aataaggtgt ctcgctcagg tttagagata
    13261 aaattaggac aaacctgtta taaatcacta ttaaaatctg atagaccatg tagtaattgt
    13321 cctcttaacg gattagaaga aaataaacat tcaaaattca aaatagagac aaatacattt
    13381 ggtacaaata tcagtatagc cagttggatt aattgcatag acggagaata taattgtctt
    13441 atagagtgta tagattcttc tttatacaaa aataaataaa aaggactatg aagatatgtt
    13501 aaatggtata actttgatac ttggtataat atttacaatt tactattttt atctcaaaat
    13561 agtttttgga ggaatttcat ttagtgagat tttcttagtt gtaggaatta tactaattat
    13621 ctatcaaata tttaagaaaa aaatcaaaga aaagaaggtt ttttatagag tgttaaaaat
    13681 aataatcagt gtttttttaa tagtatttgt agttactgag agtctaatta ttttttatcc
    13741 taaaaatagt ttagagtcaa aaagtgatta tctcttgatt ttaggagctt ctgtaaaaaa
    13801 gactatacca agtacaaccc taaagggtag attaaacaca gcattgaaat atctaaaagt
    13861 taatgataat tgttatgtag tagtatctgg tggtaaagga agtggagaaa acataactga
    13921 ggcaaaagct atgaaagatt atcttataaa aaacggtata gataagaata ggataataga
    13981 agaagataaa tccactaata cttatgagaa ttttaagtat tcaaaattta agatagaaga
    14041 acgtagtgaa agaaaattaa gtgatttaaa agtaaaaata gtaacaacag attttcatgt
    14101 tcttaggagc aaaatattag catatagaaa tggatataaa aatacgtctt tttatgctag
    14161 taaatcaaaa ctttcatttg tacctactta ctatacaaga gaattttttg cattatggaa
    14221 aacaatcttt tttgatagat aataaataga aggactagat ataaattata aatttatatc
    14281 tagtcttttt tatgtagaaa gtaagagtta aaaattattt tttcaaagct tcctgccatt
    14341 aaattagaaa atttagtctc agtattttag aaacattaat aatagtaata taaatcaata
    14401 taaaaataat tacaagatta tattaattat tcaaattata tataaaatta agaaaaattc
    14461 ttttagttta cataataaaa ataatgttaa ttaaaattat tagttttagg taaaagtacc
    14521 aaattatgca tttaagtaga ttttaagctc gatttgatta gaaaggtaca aactatcgta
    14581 gtaaaaattt aaacctattt aaaaaccaat ataaaagctt gttatttttg agaaaaataa
    14641 actctctaaa cccaattaga caaaaataaa atacagaaag ttatatctca gaatgtctta
    14701 agtaattaag tctaaaattt atgatatttt gtttggtgat ttgtaatata aaagcctttt
    14761 ttaaatttgt tcaaaataaa aaagtaaaaa ataacaaaaa aatcactgac atttcactga
    14821 caaaacacag ttttataatt atgtatttat tgaaaatact tgattattaa aaaatggcat
    14881 aaaataatac attttatgcc atttgctatt atttgataat ttttaagtta taatacaata
    14941 tactttcttt acatatataa taaaatatta aaaaaccgat atcgatattt caaacagcaa
    15001 aaatagatgt tagctattat agaaaaaaag tgcacttata ggcttaaaat gtcacataaa
    15061 agaattttaa agaataatat attatgaaca caaattttta taatctcaaa ggagtgataa
    15121 tatggcaaca gtatcaggac aaatagtttt tgatagaaac agaagtgcta ccattgattc
    15181 tggagattct ggaatagcca atgtcccagt tgtattacaa gacatagcaa ctggagtcag
    15241 actcacagtt ctcacaaatg catcaggaaa ttatgttttt actaacgttc caaatggtaa
    15301 ctatagaatt gtagaagctt ttggaactac aggaggagta ccaacaccag ggaattttgc
    15361 agcagcgata gtaggtccag ttccaattgc agaaatacca cctattagtt ctgtgataaa
    15421 tcctcctatt ggttcaacaa acttagatgg tacaacaccc aacacactat taataacagt
    15481 agcaggttca gatataacaa atcaaaatat attaaatggt cctgtgattt atacacctat
    15541 acagaatata ttggattctt gtgtatctgt atctaatata aaccttatta tagacgcaga
    15601 taatggaaca ttcggtttct tcccaccagg cacaccaagt aatacagggc ctgagataga
    15661 accttaccca aatgtgacac cagattttac gtatgttgta ccagacccaa ctaagtttac
    15721 acctttagat ggagaatata cagtacaaaa tattatgaca aatgcaatga gtaatgttat
    15781 aggagcttgg tggcgtattg ctgaccatac tacaggaaat gaaacaggaa gaatgatggt
    15841 ggtaaatggt tttaatcctg gagctgtatt ttttaaatca acagtacaag ttacacctaa
    15901 cactaatttt ttatttagta cttggatttt aaaccttttt aaggtaacag gatatccacc
    15961 accacagcta ggtgtaagaa tatttgacca aaataataat atactatatc aagcaacatt
    16021 aggagctcaa attccagtta atacaaatgc accagagtgg aaagaaatag gtactgtaat
    16081 taattctcaa aataataatc aacttacagt agaatttttt agcgagggag aaagtgttat
    16141 tggaaatgac tacgctatag atgacgtttc cttaagagaa attactgttc caacttttac
    16201 tccaataaaa acaagtaaca cagaaactgc taacataggc gatatagtca catatacagt
    16261 tacactagat aatacttgta atagcccttt aactaacgta ttttttaggg acataattcc
    16321 aaacggttta aaatttatac ctggaactgt aacggttgat ggaatatctg taccaggagt
    16381 agaccctaat ataggtttcc aacttccaga tatcggagga ggaacaagga ttgaagtaac
    16441 ttttaatgtt gtagttgaga gtattcctaa cccaaatcct actaataata tagctactat
    16501 agattactcc tatactcctg tagaaggtgg tataccaaat aatttttcag tagattctaa
    16561 tccagttcct gttgaagtaa tctcagcaga tattgaagtt acaaaattat ctgaaccttc
    16621 tatagtgaat ccaggagagg aattaatata cactataaaa gtagtaaata acggaccatt
    16681 cccatctgaa aatgtggttt taacagatga tgtaccagac tctattataa attcagaata
    16741 ttcattggat ggaggagtaa gttttcaacc atggaatgga agtttaaata tagggacatt
    16801 agaattagga gcgacaagag ttattataat taggggtatt gtaaatccaa caacagtagg
    16861 aattataaga aatacagctg tagtatcttc aactacagca gacccaaatc ttaataataa
    16921 tacatctaca atagagacag aagtgaattt attggcagat attttggtaa tgaaaacagc
    16981 agaacctaat tcagctgttc caggtacttt attaagatat actattcaag tagcaaactt
    17041 aggaccagca aatgctgaga atgtaatatt aaatgatgat ataccagatg ttattttaaa
    17101 tccagaatat tcactggatg gaggagtaag ttttcaacca tggaatggaa gtcttaatat
    17161 aggagcttta aactctggaa tttcattgac agttttaata caaggaacag ttagtttaaa
    17221 ttcttcagaa tatatagtaa atacagcaac agtttcctca actacacctg acccagattt
    17281 aagcaacaat atatctacta ttatcacgcc agttaatcca caggcaggta tttctattat
    17341 aaaagtggct aatgaggatg tagctgttcc aggagaagag tttgtatata caattgaaat
    17401 ttttaatgaa ggaccatcta atgctatgaa tgtagtttta acagataata taccagatgt
    17461 tattttaaat ccagaatatt cattggatgg aggcgcaagt ttccaaccat ggaatggaag
    17521 tcttaatata ggtacagttg caccagggca attaataaga attatcataa ggggattagt
    17581 aagttcaact gctacaggga atattactaa tacagcagaa gtaagtgcag aggtaccaga
    17641 accagttact gattcatcaa cagtaataac tcctgtagtt gcatcagcag atatagaagt
    17701 aataaaaact agcaatatgg atacagcagt tccaggagaa atttttagtt atactataac
    17761 tgttacaaat ttaggtccat ctgctgctca gagtatcgtt ttgacagatg atataccaga
    17821 tattatttta aatccagagt attcattaga tggaggagta agctttcaac catggaatgg
    17881 aaatcttaat ataggcactt tggatacagg ggaaataaga agtattataa taagaggaac
    17941 aataaaccaa acatcagtag gcacaattat aaatacagca acagtaagtt caactacacc
    18001 tgacccaaat ccagataata atacttcaac agtggaaaca gatataagtc cattagcaga
    18061 tatttctgtg ataaaaggca acgaaccact tgctatacaa ggtgaaagat ttatttatgg
    18121 aattgaaatt gtaaatgcag gaccatcttt ttcagaaaat atagtcttga cagacaatat
    18181 accagcttct attttaaatc cagagtactc aatagacaat ggagtgactt tccaaccatg
    18241 gactggaagc cttaatatag gtactttaga tgctggagag ataagaaatg tcataataag
    18301 gggaacagta agtcaaacag cagtaggaac aattataaat acagcaacag taagttcgac
    18361 tacacctgac ccaaatctaa ataacaatac ttcaacatca gaagcagagg taagttcatc
    18421 agcagatatt tctgtagtaa aacgaagcaa tcagaatgtt gttgtaccag gagatgtact
    18481 aaactataca attgaggtga gaaatgcagg accatctact gctcagaatg taactttaac
    18541 agataatata tcagcttcta ttttaagtcc agaatattca atagataatg gagtgacttt
    18601 ccaaccatgg actggaagtc ttagtatagg cactttgtat gctggagaga taagaaatat
    18661 tataataagg ggaatagcaa gtgaaacagc aataggtaca attataaata cagcaacagt
    18721 aagttcaact acacctgacc caaatccaaa taataacact tcaacatcag aaatagatat
    18781 aagttcatca gcagatattt ctataataaa attagcaaat aaaacagaag catgtgtagg
    18841 agaacaaata gattttgtaa tagtagtatc aaatgcagga ccagaaaatg ctcaaaatgt
    18901 tactttaata gacaatgttt cagataagct taagaaaaca gtattttcac ttgatagagg
    18961 tgtaagtttc caaccttgga ctggaagtat taatataggt atactaccag ctggaacttt
    19021 aagagttatt ctattaagag gacttataaa atcaacatgt cttgataaat taacaaatat
    19081 tgcagaagtt acttcaacaa caccagattc agaccttaac aataatatat caagagtgca
    19141 agtagaaata aaacaatgtt gttctaacga ttgctgttgt aattgttgtt gtaataactg
    19201 ttgtaattgt ttttttaatg attgttgtaa tgattgtggt tacaaggatt gttgttgtaa
    19261 ttgttgtaaa aatgactttt ggtgttgatt ttatacaata attttgtata tcttaaatta
    19321 aactgaaata aaaaattcat atatgagtaa aatatttttt aaatattaat aagttttcta
    19381 ttttcgatat ggaccacatt cgtaatacta
//
LOCUS       DBGJFK010000079        18419 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.079, whole genome shotgun sequence.
ACCESSION   DBGJFK010000079 DBGJFK010000000
VERSION     DBGJFK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18419
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.079"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..351)
                     /locus_tag="ACOIAP_003032"
     CDS             complement(<1..351)
                     /locus_tag="ACOIAP_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2639909.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGT"
     gene            918..1280
                     /locus_tag="ACOIAP_003033"
     CDS             918..1280
                     /locus_tag="ACOIAP_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639910.1"
                     /translation="MKIRKRGFISIECVISIAILYVAVYLVSTSLYSCYSFVSRNISD
                     RKMLSTAKKYIEDEKYRIQNSKYELIENKIEKNYINGYEISSRVEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            1264..1983
                     /locus_tag="ACOIAP_003034"
     CDS             1264..1983
                     /locus_tag="ACOIAP_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639911.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFKLGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDISNSEGEFREYFLGNNMIECIKKIKDTSYSS
                     VEGLSLKVENNTIYDREDFFEFDIESSVREKEFLKTIKVRVKIKNPWVGIDIEDYMNK
                     SNNNKIYDKKFNNYKASENNEILNQFKNESENISNQEVVEPTEEDNEEYEEELKQNII
                     ENIKKNFDEKKLVQVYKYRGV"
     gene            2009..2422
                     /locus_tag="ACOIAP_003035"
     CDS             2009..2422
                     /locus_tag="ACOIAP_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639912.1"
                     /translation="MIELIVSISIILLIVTLSFPKDNIENHKINLFARQLCSDIRYVR
                     RINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIILPKNVKIARSIETIKFKSDGSP
                     QKASTIEIYNNRLRKIITITPVSGRVLLKEGKYET"
     gene            2412..2942
                     /locus_tag="ACOIAP_003036"
     CDS             2412..2942
                     /locus_tag="ACOIAP_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639913.1"
                     /translation="MKHKYGYLLLESVVSLSSMLIMILVLYSIFLSTISLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIINVSNYEDTFKKATSIKCRYVDENVNNNEESISNK
                     EIILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSINNNGQYVNIKLKLSKRSQK
                     YETEFKIKVWNFSENI"
     gene            3255..3812
                     /gene="efp"
                     /locus_tag="ACOIAP_003037"
     CDS             3255..3812
                     /gene="efp"
                     /locus_tag="ACOIAP_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGZ2639914.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYDQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            3904..4359
                     /locus_tag="ACOIAP_003038"
     CDS             3904..4359
                     /locus_tag="ACOIAP_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1247 N-terminal domain-containing protein"
                     /protein_id="HGZ2639915.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFAEAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            4521..5231
                     /gene="rnc"
                     /locus_tag="ACOIAP_003039"
     CDS             4521..5231
                     /gene="rnc"
                     /locus_tag="ACOIAP_003039"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGZ2639916.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGV
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINEDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            5285..6355
                     /locus_tag="ACOIAP_003040"
     CDS             5285..6355
                     /locus_tag="ACOIAP_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006448 - regulation of translational
                     elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongator complex protein 3"
                     /protein_id="HGZ2639917.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPTDTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYSPFTLEESVN
                     IVKKVLALFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKLGVILKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            6383..9937
                     /gene="smc"
                     /locus_tag="ACOIAP_003041"
     CDS             6383..9937
                     /gene="smc"
                     /locus_tag="ACOIAP_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGZ2639918.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDIYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKILEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELENNKLSSSGELSALQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNVRDENINLEITELNKNIDIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSTNLQDSISEHSKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KINNIKHEISQLELKRESLDKDIKNIKSEIDSHESKIKDLEKSIIIKSTSIENIESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKRDNVRKDIEELDNLYNQNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEAYNSIVRDIKRISGENYELEEKNKQLEESLNYEE
                     QEIIKLQDSIATEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRNLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAKEITDII"
     gene            9964..11235
                     /gene="ftsY"
                     /locus_tag="ACOIAP_003042"
     CDS             9964..11235
                     /gene="ftsY"
                     /locus_tag="ACOIAP_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGZ2639919.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDEEEVVDSVDSLENLEETIFSGLEE
                     EVIDKDEDIEEKTEESVNNEGTEEIENFEKIDVEMDSDGKEVENISDNDSQEEIIEEL
                     ENYDEIESKEIEAKEEKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELLEDL
                     EEILITADVGVNTTMDIIERLRDKIKQKGIIEPIKVREELKSIVEDILTNENSTLDIE
                     PAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWANRTN
                     VDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKIVDR
                     EFPEAKREVLLVVDATTGQNAVIQAKTFKEVADITGIVLTKLDGTAKGGVVLAVKSEV
                     DVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            11338..11706
                     /gene="ylxM"
                     /locus_tag="ACOIAP_003043"
     CDS             11338..11706
                     /gene="ylxM"
                     /locus_tag="ACOIAP_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048500 - signal recognition particle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxM family DNA-binding protein"
                     /protein_id="HGZ2639920.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            11703..13055
                     /gene="ffh"
                     /locus_tag="ACOIAP_003044"
     CDS             11703..13055
                     /gene="ffh"
                     /locus_tag="ACOIAP_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGZ2639921.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEADVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIARGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            13093..13365
                     /gene="rpsP"
                     /locus_tag="ACOIAP_003045"
     CDS             13093..13365
                     /gene="rpsP"
                     /locus_tag="ACOIAP_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGZ2639922.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            13430..13657
                     /locus_tag="ACOIAP_003046"
     CDS             13430..13657
                     /locus_tag="ACOIAP_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HGZ2639923.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            13765..14280
                     /gene="rimM"
                     /locus_tag="ACOIAP_003047"
     CDS             13765..14280
                     /gene="rimM"
                     /locus_tag="ACOIAP_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGZ2639924.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLSVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGIEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            14289..14984
                     /gene="trmD"
                     /locus_tag="ACOIAP_003048"
     CDS             14289..14984
                     /gene="trmD"
                     /locus_tag="ACOIAP_003048"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGZ2639925.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSIAKH
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            15158..15508
                     /gene="rplS"
                     /locus_tag="ACOIAP_003049"
     CDS             15158..15508
                     /gene="rplS"
                     /locus_tag="ACOIAP_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGZ2639926.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            15830..16726
                     /gene="ylqF"
                     /locus_tag="ACOIAP_003050"
     CDS             15830..16726
                     /gene="ylqF"
                     /locus_tag="ACOIAP_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGZ2639927.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADKDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALKLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEIPENVKR"
     gene            17115..18407
                     /gene="brnQ"
                     /locus_tag="ACOIAP_003051"
     CDS             17115..18407
                     /gene="brnQ"
                     /locus_tag="ACOIAP_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGZ2639928.1"
                     /translation="MGKTKDIIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIKPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKVI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLHSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         7789 a         1735 c         3403 g         5492 t
ORIGIN      
        1 tgttccgata gggtcttgta gagatacttg agttttattt tttttgttag acctaatatt
       61 cattaaaatt tcattttcaa tacatctaga agcatatgtt gctaatcgag ttcctttatc
      121 tatgttataa gtttctatag ctttaattaa tcctattgta cctatagata ttaaatcatc
      181 ctggtcttct gttgaattat tatatttctt tgctatataa gctactaatc tcatgtttct
      241 ttcaattaat gtatcttttg cacttttatc gttttctatt ttaaatttag ttaaatactc
      301 aatctcttct tcaggggtta agggtttttc aaaagattta agagctgcca ataggtcacc
      361 cccttttcaa cggtcacttt aaattatatg aaggagactt atccaagttg cctgttatct
      421 aataaaataa tatgcatatt tttagaattt aaaacatata tttgcaaact tttagatgga
      481 atatgacata aagagtggga atttaaattt aagtttttgt tgtatatata tgaaacaagg
      541 cgaaggaatt attgatttat aaagtataaa ttgaaactga ggtgtcaata aatataaagg
      601 aaatagtatt tatgtatgtt ttgatgttga ggtaaaaaat taatgaaaaa cattagaatc
      661 tataaaaaat atgaatatag gaggtgtaat tttgcaataa ttaaaaaagt aaatgcaatt
      721 aattatttgg ataaagttga ttgcaagtaa aaagtattag tcatagttaa tactgttaag
      781 ggtgaaggtg gtgtgttaat ctgtatgtgt gtaggaagag ttttgagtta taatgaaaaa
      841 acttataaaa ggtatttatg aaaaacttat agttaaccat ctatatataa aatattattt
      901 aggggttgtt tttattattg aaaataagaa agcgtggttt tatatcaatc gaatgtgtaa
      961 taagtattgc tatattatat gtggctgttt atttagtttc tacatcattg tatagttgtt
     1021 atagttttgt cagtagaaat atatctgaca gaaaaatgtt aagtactgca aaaaaatata
     1081 tagaagatga gaagtataga atacaaaata gtaagtatga gttaattgaa aataagatag
     1141 aaaaaaatta cataaatgga tatgaaatta gcagtagagt agagcaaatt ttagattatt
     1201 atcaatgcta tgaaataaat atagagataa aaaatgaatt taaaaaattg aggtttaata
     1261 gctatgttac tagaaaataa aggctccata ttaataataa cattgataat attctctatt
     1321 ataagtactg tgtgtattat gtgtataggt ttaatttata cacataataa tatgtttaag
     1381 ttaggataca aggacattca actaaaagaa atttctttaa gtggaataga aatatcagta
     1441 agtaatgtac tttcttgtgt tgaggaagct attgatatat ctaatagtga aggtgaattt
     1501 agagaatatt tcttaggaaa taacatgatt gaatgtataa aaaaaataaa agatacttct
     1561 tatagtagcg tagaaggact ttctttaaaa gtagaaaata atactattta tgatagagaa
     1621 gacttttttg aatttgatat agaaagtagt gttagagaaa aagaattttt aaaaacaata
     1681 aaagtaagag tgaaaattaa aaatccatgg gtaggaattg acattgaaga ttatatgaat
     1741 aaatctaata acaataaaat ttatgacaaa aaatttaata attataaagc atctgaaaat
     1801 aatgaaattc taaatcaatt taaaaatgaa agtgaaaata taagtaatca agaggttgtt
     1861 gaacctacag aagaagacaa tgaggaatat gaagaagaac ttaaacaaaa cataattgaa
     1921 aatataaaaa agaattttga tgaaaaaaaa ctagtacagg tatataagta taggggtgta
     1981 taactttgaa aaaagaagga atgtgactgt gatagaatta atagtatcta ttagtataat
     2041 actcttgata gttacattat cttttccaaa agataatatt gaaaatcata aaataaattt
     2101 atttgcacgt caactttgtt cagatataag gtatgttagg cgaattaata tgtttagtaa
     2161 ctacaataca tatatatact atataaatca aggtaaacat gaaggttatg tattgagaaa
     2221 agatggtaaa aatattaagt caataatact gcctaaaaat gtaaaaatag ctagaagtat
     2281 tgaaacaata aagtttaaat ctgatgggtc acctcaaaag gcatctacaa tagagatata
     2341 taataataga ttaagaaaaa ttataacaat aacacctgta agtggaagag tacttctgaa
     2401 agagggaaaa tatgaaacat aaatatggtt acttactttt ggaaagtgta gtatcattgt
     2461 cctcaatgtt gataatgata ctagttttat attctatatt tttgtctaca ataagcttaa
     2521 aattaaaagt agaagataag atagaactac aacaacaaag tcttgaaatc ataaaatcta
     2581 tggaaggaat tattagcaat tctatgggaa taataaatgt atctaattat gaagacacat
     2641 ttaaaaaggc aacatctata aaatgtagat atgtagatga aaatgtaaat aataatgaag
     2701 aaagcataag caataaagaa attatattga atgaaagacg aaataagtta tttgtaaatt
     2761 ctttaaatgg cgaaagtagt caagcaggtg gttatgaaat aggagattat gtagatgaga
     2821 tgtatgtatc aatcaataat aatggccaat atgttaatat taaattgaaa ttatcaaaac
     2881 gtagtcaaaa atatgagact gagtttaaaa taaaagtatg gaattttagt gaaaatatat
     2941 aaaaatacat aaatttatag agaaagaaat aatatcaata agtcatataa aatataatta
     3001 ttgagaacta tataaataaa taatatcaat atgtaaagtg catagattaa gaatatagag
     3061 gataataata aaaatataga ataagtaatt tgccaaatac ttgtttatat tgtataactt
     3121 atgatattat gatattagta aaaatttgta atcctgactt gacagaattc aagtaagaga
     3181 tataatttta aaggcatagt aatgtaaaat ttactaaaaa ataagaaatt tattttaata
     3241 tggaggaaca aaaaatggta tcagcaggtg attttagaaa aggtgttaca tttgaaaaag
     3301 atggacaacc atgtttagta gttgattttc aacacgttaa gccaggtaaa ggagctgctt
     3361 tcgttagaac taaatacaaa aacttaaaaa caggagctat aagagaagaa agtttcaatc
     3421 caagtgaaaa attccctaag gctgttatag atacaagaca aatgcaatat ctatacaatg
     3481 atggtgagtt atattatttt atggatcaag aaaattttga acaaatacca ttaaattatg
     3541 atcaagttga agatgcaatt aagttcttaa aagaaaatga agttgctaca ataagatttt
     3601 accaaggaca accattccaa gtggaagctc caaactttgc agagctagaa gttacagata
     3661 cagagccagg tataaaaggt gatacagcaa gtaatgtaac taaagcagct acagttgaaa
     3721 ctggggcagt cgttcaagtt ccattattta taaatactgg agataaagta aagatagata
     3781 ctagaacagg tgaatattta tcaagagtat aaaaatttat gtatataaaa gcttatatgt
     3841 cttaataata taagatatat gagcttttag tttatatata aaaaagaaag cgaggggtgt
     3901 tacatgaaac atttatatga agaagttgca tacttaaaag gcctagcaga aggactagaa
     3961 ataagtgctg aaagtaaaga agggaaaatg atacataaaa tagttgatgc attagaagta
     4021 tttgcagagg ctattgtaac attggatgaa gaacaagaag aacttcaaga ttttgttgaa
     4081 tctatagatg aagatttagc agatttagaa gaagatattg ctgacatgga agaagatctt
     4141 tatgaagaag atgacgatga ggatgatgag gacttcagct atatagaaat ggaatgccca
     4201 aattgtggag agttagtaga aatagacgaa gatttgttat atgatgatga agtagatgtt
     4261 gtttgtcctg attgtaaggc tgtgatatta tcatcagaag atgattgtga tgatgattgt
     4321 acatgtggtg gttgttcaag ttgtgatgat agagagtaaa aattcataag aattaaaact
     4381 gcctatgatg cctatgagat attttgcttc ataggtagtt ttatttttat gaggaaggta
     4441 ttatgtattt tggttttgca atacttggac aaaaatagta cactagaatt tatagaatag
     4501 gattttggag ggatgtaaat atgaaaataa gtaaaaaatt gctagataat atacaaagat
     4561 ttgaaaatgt tataaattat aaatttaaaa ataaagaata tatactagaa gctcttactc
     4621 atagttcata ttctaatgaa aataaaaaat ataattttaa cgaaaggttg gaatttttag
     4681 gagattcggt tttaggcata gtgataagtg attatttgtt taacgaagaa gctaatctgc
     4741 ccgaagggga actaactaaa cttagagcaa atatagtttg tgaagattcg ttaagtgaag
     4801 tagctaatga tataaattta ggtgtgcaca tgttattagg tagaggagaa gaagcaacag
     4861 gaggaagaca taggacttca atattagcag atgcatttga agctgtaata gctgctatat
     4921 atcttgatgg aggatttgaa agtgcaagac agtttatact tcatcatatg gaaaatataa
     4981 tttatgattc aagaaaagga aatatattta gagactacaa aacgcatctt caagaagtgt
     5041 tacaagggaa tggagaaaat aatatctggt acaggcttat agaagaaaaa ggaccagacc
     5101 ataataaaag atttgtaatg gaagttggaa ttaatgaaga tgtattgggt ataggagaag
     5161 gcaaaagtaa aaaagaagct gaacagttgg ctgctaaaat agctttaaag aaaaaattat
     5221 gggaaaaata aatataatat gtaaaaatat aaaaagaaat aattatatta gaaggatgtt
     5281 gtagatgaaa aagagaatta tacctatatt tgttcctcac aagggatgtc ctcatgattg
     5341 catattttgt aatcaaaaaa aaataacagg tgtgagtact gatgttacta gtgaagatgc
     5401 aagaaatata attgaagaat gtttagagac tatagataaa gatgcagatg tagaaatagc
     5461 attttttggt ggtagcttta ctgctataga tattgatata caaaaaagtt tattatcagt
     5521 tgctaaagaa tatgtagaaa aaggtcttgt aaaagatatt agaatgtcta caagaccaga
     5581 ttgtattgat gaagatatat taagtatgct aaaagaatat aagacaagta taattgaact
     5641 aggagtacaa tctttagatg aaaaagtatt attagatagt ataagaggtc atcaatctga
     5701 aattgtatac aagagttcaa agatgataaa aaatagtgga attaaactcg gattacagat
     5761 gatgattggt cttccaactg atacagaaga aaagtgtata tttacagcaa aaaaatttgt
     5821 agagctaaaa ccagattgtg ttagagttta tccaactttg gtagtaaaag acacaggact
     5881 tgaaaagtta atggaacaaa ataaatatag tccatttact cttgaagaga gtgtaaacat
     5941 agtaaaaaaa gttcttgcac tgttttatgt taataatatt aatgtaataa gagttgggct
     6001 tcaagctact gatgatatac aaattggaaa agctgtttta gcaggaccat atcatcctgc
     6061 atttagagag ttagtagaag ctgatatgat aaaagattat ttagaatttg ttattttgca
     6121 aaataaaaat ataaagcaga tgttggtcaa atctaataaa aagaatattt ctaaaatcat
     6181 aggaaataaa aaaacaaatg ttaaatatat ggaagaaaaa cttggtgtga ttttaaaaac
     6241 acaagaatca gatttagata taaatcaatt agaaattgtg ttagatggaa aaagtttaat
     6301 tagtgctaat atgagagaca ttcatagaaa attgtatgac atttatgacc tttagtttta
     6361 ataatgaagg gagagaaaag atttgtattt aaaaagacta gagttaaagg gatttaaatc
     6421 ctttccagta aaaacagata ttatttttaa agaaggaata acagccatag taggaccaaa
     6481 tgggagtgga aaaagtaata tatctgatgc tgtaagatgg gtattaggag aacagagtat
     6541 taagagcctt agaggtgata aactcgaaga tgtaatattt gcaggtacag atacaaaaaa
     6601 acctatgaat tattgtgaag tggctcttac tattgataat tctgaaaatc aattggaatt
     6661 agattttaca gaagtaacta taagaagaag ggcttataga aatggtgaaa gtgaattttt
     6721 tctaaataat aaaagttgca gattaaaaga tataaaagaa gtctttttag atactggtat
     6781 tggaaaagat ggttattcaa tcatagaaca aggaaaagta gatgaaatat taagtaataa
     6841 tcctttaagc agaagaaaag tttttgatga agcttgtggc atatcaaaat atagatataa
     6901 aaaacaggaa gcagaaagga atttaagcaa tacaaaggaa aatttagaaa gaatagatga
     6961 tatatatata gaaattgaaa atcaattaaa acctcttttt aatcaacaaa ccaaggcaaa
     7021 aaaatactta gaaataagtg aaaaattaaa aatacttgaa gtaaatagct ttataagaga
     7081 aattgaagga atagaaaaag aattaagtga ggttaatgaa catcgtaagg ttattgaaaa
     7141 ggaactcaat gaaaaagaag aacaaaaaaa tgttgtagag aaaaagcaag aagatattaa
     7201 taaagaggta gaggtattac aggatgtaat tgaaaaatct gtagattata taaattcaat
     7261 caaaggagtt atatcaaaaa aagagtccca aataaattta attaaggaaa gaataagaaa
     7321 ttttacgaat gaaattagta gaaaaaattt agaaataaat gatataaaag agaaactaaa
     7381 tgaaaataag caatacataa aagaattaga aaataataaa ttatcaagta gtggagaact
     7441 atctgccttg caggaaaata taaaagtatt ggaagcaagt aaagataaac aaaaaattaa
     7501 gttagaatcc ctaaataatg agatagaatt attgaaagaa agtataattg atatattaaa
     7561 taagaaacaa gagtttagta ataagttgtc cactttaaac gcaaataaag aaaatatgaa
     7621 tgttagagat gaaaatataa atttggagat aacagaacta aacaaaaata ttgatataaa
     7681 atcatctgaa ttagatacta taaataaaga gtttaatatg caaaatgaaa atttaaagaa
     7741 tgtaaataat aggcataaag aattatcaac taatttgcaa gattcaatta gtgagcacag
     7801 taaactagaa gatgaaatac agaaaagtaa atataatcta aatggatata attcaaaatt
     7861 aaatgtctat atagatatgg aaaatcatta tgaaggattt aatagaggag taaaagaagt
     7921 actaaaaaat aaaaatttaa aaggtgtaca tggagcatta ggacaaatta taaatgtacc
     7981 tgaaaaatat gagaaatcta tagaagcagc acttggtgct tatatgcaaa atattataac
     8041 tgataatgag tttagtgcta agtctgcaat aaactatcta aaacagaata atttgggtag
     8101 agtaacattt cttccattaa atataattaa atcaaataaa ataagcctag gaaatctaaa
     8161 agcaaatact aagttcatag gaatagcaag tgatttaatt acatttgatg aaaaatatag
     8221 aaatataatt gaaaatatac ttggaagaac aatacttata aataatatag atgaggggat
     8281 aaaatttgca aaagaaactg gacataggtt taaaatagta actttagatg gtgaaatctt
     8341 aaatccagga ggttctttga ctggaggaag tctaaagact aatgggaata tactatcaag
     8401 aaaaagatac attaatgaat atacagaaaa gataaataat atcaagcatg aaatttcaca
     8461 attagaatta aaaagagaat ctctagataa agatataaaa aatataaaga gtgaaattga
     8521 ttcacatgaa agtaaaataa aagatttaga aaaaagtata ataataaaaa gtacaagcat
     8581 agagaatatt gaatctgaaa ttgaatcgtt aaaaggtagt attactaaat tagagaatga
     8641 gaaaaatgat ttaaattcta acctaaatta tacacttgaa aaaagagata atgttagaaa
     8701 agatatagaa gagttagata atttatacaa tcaaaataaa gaaaaaattg atgcattgaa
     8761 tgaggaaata aaaagataca atgatttata tgataaagaa aaatctgaat ttgatgaatt
     8821 aaacttaagc ttagtgaaga aaacagaagc ttacaatagt atagttagag atataaaaag
     8881 aatatctggt gaaaattatg agctagaaga aaagaataaa caattagaag agtcattaaa
     8941 ctatgaagaa caggaaataa ttaaattaca agattctata gctactgaag aaaaagaaaa
     9001 agaaaatcta acaaaacaac taggagatag taatagaaat cttgaaacta gaaaaatagc
     9061 aaaagatgat ttgaaaaata gttttgatga aattaataaa gaattaaaaa ctatagatag
     9121 acagcatata gagcttaaag aaagtttatt taaagttggt ggaagattag aaagattaaa
     9181 aactagtcaa gacacatata taaataagtt gtttgagcaa tatgatatga ctttagtaca
     9241 agcattggaa attaaagatg aagatttgga tatagataga aaattcttag aaagtctaaa
     9301 gagagaaata agaaatcttg gaaatataaa tatagactct ataaaggaat atgaggaaat
     9361 aaaagaaaga tacgattttt atagtgaaca aaagcaagat ttagaagagt ctatggaaga
     9421 gatagaaaaa cttatacata ctttagaaga aaatatgaaa tctgaatttg aaattaagtt
     9481 tgaagaaata agtaaaaatt ttaaatatgt atataagaga ttatttggtg gtggttgtgg
     9541 agaattaact atcttagata aagaaaattt attagaaagt gatatactaa taacagctca
     9601 acccccaggt aaaaaaatga aaaatttaaa cctcttatct ggtggagaaa aagctttaac
     9661 ggcaataagt atattatttg ctatattgat tacaaagcca acaccgtttt gtatattaga
     9721 cgagattgaa gctccacttg atgatgcaaa tatatttaga tttggagagt ttttgaagga
     9781 tttatctaaa gagactcaat ttatatcagt aactcatagg agaggaacta tggaagctgc
     9841 tgattatatc tatggagtta caatgcaaga aaaagccatt tcaaaagtta ttagtttaaa
     9901 attaaaagaa gctaaggaaa taaccgatat tatataactt agattgacat aggaggaata
     9961 acagtgttaa aaaaattatt tggttttgga aaagacaagg aaaaggaaat agaaaagaaa
    10021 gatgaagaag aagtagtaga cagtgttgat agtctagaaa acttggaaga aaccattttt
    10081 tcaggacttg aagaagaagt gatagataaa gacgaagata ttgaagaaaa aactgaggaa
    10141 agtgtcaata atgaaggcac tgaagaaatc gaaaactttg aaaaaataga cgttgaaatg
    10201 gatagtgatg gaaaagaagt agaaaatatt tcagataatg attctcaaga agagataatc
    10261 gaagaattag aaaattatga tgaaattgag tctaaagaga tagaagctaa agaagaaaag
    10321 aaagttaact tgtttgaaag actaaaacaa ggattgacaa aagcaaagca aggaataact
    10381 gatagaatag atgaggtttt aaaatcatat acaaaaatag atgaagaatt acttgaagat
    10441 ttagaggaaa ttttaataac agcagatgtt ggtgtaaata caactatgga tataattgaa
    10501 agactaagag ataaaataaa gcaaaaaggt attattgaac caatcaaggt aagagaagaa
    10561 cttaaatcta tagttgaaga tattcttaca aatgaaaact ctacactaga tatagaacca
    10621 gcaccatgta taatattaat ggtgggtgta aatggggtcg gtaagactac tacaataggt
    10681 aagctagcaa atagatacaa aaaagatggt aaaaaagttt tattagcagc agcagataca
    10741 tttagagctg cagcaacaga gcaattagaa atttgggcaa atagaaccaa tgtagacata
    10801 ataaaacacc aagaaggagc agaccccgga gctgtagtat ttgatgctat aaaagccgca
    10861 aaagctagaa aaacagatgt attaatatgt gatacagcag ggagattaca caataaggct
    10921 aatcttatga atgaacttgg aaaagtattt aaaatagtgg atagagaatt tccagaagca
    10981 aagcgtgaag tacttcttgt ggtagatgct acaacaggtc aaaatgcagt tattcaagca
    11041 aaaaccttta aagaagttgc agatataaca ggtatagtac ttacaaaact tgatggaact
    11101 gcaaaaggtg gcgtagtgct tgcagtaaaa tcagaagtag atgtgcctgt aaaacttatt
    11161 ggagttggag aaagtgtgga agacctacaa gatttcaatg caaaatcatt ttcagatgca
    11221 ttatttggta actagtgttc ttttaaaaat aatggttgac aagagtgttt ttatgatata
    11281 aaatacaata gtgtaaagta aataaccttt acagtatact gctaggaagt gtaagatatg
    11341 aatatagaaa aaatggtcga aataggattg ttatttgaac agtataaaga attattaact
    11401 gacaagcaga aagaaatagt tgctctatac tatgaagaag attattcttt aggtgaaatt
    11461 agtgagaatc tgaatgtatc aagacaaggt gtgtatgata ccttaaagcg ttcagaaaaa
    11521 atactaagag attatgaaga gaagttacac ttagtatcaa agattcaaga gcaggaaaaa
    11581 aatattaaga ttataaaaga taaaattatt gacattaaag aagatttatt gcacaataga
    11641 gattgtgcta atttaatccc taagctagaa aatatagaag atgtatgtag ggagatgata
    11701 aaatgatatt tgaaggattg tctgataaac tacaaggggc atttagtaag ttaaaatcta
    11761 aaggaaaact tacagaagca gatgtaaaaa atgctatgag agaagttaaa cttgctcttc
    11821 ttgaggcaga tgttaacttt aaagtagtta aagatttcat aaaaaaagtt caagagagat
    11881 gtgttggaca agaagttatg caaagcttaa ctccagctca gcatgttatc aaaattgtaa
    11941 atgaagagct tacaagtcta atgggagatg tacaaagtaa agtaatgatt tcctcaaagc
    12001 ctcctacaat tttaatgatg gttggattgc agggtgcagg taagactact acagcaggaa
    12061 aacttggagg atattttaaa aagcaaggta aaaaacctct attagtagct tgtgatattt
    12121 atagaccagc agctataaaa caacttcaag ttgttggaga aaaattggat atacctgtat
    12181 tcaatatggg agacaaagaa aatccagtaa atattgcaaa agcaggttta agccatgcaa
    12241 ttaaaaacgc taatgattta gttattatag atacagctgg tagacttcat atagatgaag
    12301 tacttatgga tgagttaaag tctattaaat cagaagttaa gccacatgag atacttttag
    12361 ttgtagattc tatgacaggt caagatgctg taaatgttgc agaaagcttc aatgaggcac
    12421 ttggtgttga tggagtagta ttaactaaat tggatggaga tactagaggt ggtgctgcac
    12481 tttcaataag agcagttaca caaaagccta taaaatttat ggggatggga gaaaagctag
    12541 atgatataga acctttccac ccagatagaa tggcatcgag aatattaggt atgggagatg
    12601 tcttaagctt aatagaaaaa gcgcaagaaa acatagactt agagaaagct aaggaattag
    12661 agcaaaaaat taaaaaacaa gagcttgatt ttgaagattt cttacaacaa atggaacaaa
    12721 tacaaaatat gggacctctt gacaagatac ttggtatgat acctggtatg ggaaatgtaa
    12781 aagaccaact tggagatgta gatttgaatg gtaaagaaat gaagagaaca aaagccataa
    12841 ttcagtcaat gactacatat gagagacgaa acccaggagt attaaatgct tcaagaaaga
    12901 aaagaatagc tagaggcagt ggaaccagtg tacaagatgt aaatagactt ataaaacaac
    12961 ttaatgaaat gaaaaaaatg atgaagatgt ttgctggttc gcaaaagagt atgaagaaaa
    13021 ggggcggctt aggcggttta ccttttttta aataaaatat aaaaaagtaa aaattattcg
    13081 gaggtgactg taatggcagt taaaataaga ttaaaaagaa tgggagctaa taaaaaacct
    13141 ttctacagaa tagtagtagc tgattcaaga gctccaagag atggaaaatt tatagaagaa
    13201 ataggatact ataatccaat ttctgagcct aaacaagtaa gaataaacga tgaaaaagct
    13261 ataaaatggt tagctactgg tgctcagcca acagaagtag ttaaaaaatt acttgtaaaa
    13321 aacggagtaa tagaaaaatt cgaagcttct aaacaagcaa aataattttt tcttggcaat
    13381 cagtttaagt aagtactcat tgctaaggtt actttaggag atgaaatata tgaaagagct
    13441 agttgtagat atagctaagg ctctagttga taatcctgac tcagttgttg ttgaggaatt
    13501 tgaagataat gacggtatcg ttttaaagct tacagttgct caagaagata tgggtaaggt
    13561 tattgggaag cagggaagaa tagctaaagc tataagaact gttgtaagat ctgttgcaaa
    13621 tagagaaaat ataaaagttt ctcttgagat agtataaaat aggaggatta ggtataatgc
    13681 ctagtccttt ttatataaat ttgtacttta agattttatg atgatatgac cacataagat
    13741 taaatttttt aagaaggtga taacatgaaa gaaaaattaa ctcattttaa ggtaggtcaa
    13801 atagtaaata cacaaggtct aaaaggtgag gtaagagttt atccacttac tgatgatata
    13861 gagaggtttg atgaattaaa agatttctat ttgggaaaag atttaaataa taaattgtct
    13921 gttgaaaaag taagatacaa aggttctatg gttataatga agataaaagg tatagatagc
    13981 atagagaaag cagaaaaact aaaaaataaa tttatgtatg tatctagaga agatagcaga
    14041 gagcttgaag aaggcgaatt ttttatagca gatatgattg gaatagaagt tttaaccgta
    14101 gatggaaaat atgtaggaat attagaagat gttcttcagt attcagcaaa tgatgtttat
    14161 gtagtaaaag gtgaggaaga taaagaattt atgataccag ctataaaaaa atttgtacct
    14221 acaatagata ttgatgaaag aaaaatgatt atagacccta ttaagggaat gatagattag
    14281 gtggtaatat gagatttcat ataatgacac tttttccaga aatatttaat tcgtatatgg
    14341 atgaaagtat aatgaagaga gcagttgaaa aaggtataat tgaggttcat atatataata
    14401 taagggattt ttctaataat aaacataaaa aagtagatga ttatccattt ggaggaggag
    14461 ctggaatggt aatgactcct caacctatat atgacacgta taagcatata ataacaactc
    14521 ataatataaa taatccaagt gtaatttatc ttactccaaa aggtaaggta tacaatcaat
    14581 ctatagcaaa gcatatgtct ttaaaagaag atataatact gttatgtggt cattatgaag
    14641 gaatagatga gagaatcatt gatttaatag ttactgatga aatttctatt ggagattatg
    14701 tattaactgg aggagagctc ccagcactta taatgataga ttctatatca aggttaatac
    14761 caggtgtatt aaaccaagaa gaatcatttg aagaagaatc atttaaagat aatttattgg
    14821 aatatcctca ttacactaga cctagagatt ttgaaggatt aaaagtacca gaagtgcttt
    14881 tatcagggaa ccataaaaag atagatgaat ggagaagaga agaatctata agaataacca
    14941 aagaaagacg atttgattta tataaaaagt ctaatgaaaa ataaaaatat aataaatatg
    15001 tatacaataa agtacctata aatggaatta aaaacataaa agtgcttgta ataactattg
    15061 aagtatagta taatataaaa tgttgaaaat acgggcgttc ctctgtttac actggtcggg
    15121 tagttaagaa cgtctatgat atctaggagg aagaaagatg aatgaaatgc taagagcaat
    15181 tgagcaagaa caattaaaaa atgaagttcc taattttgga cctggggaca cagttaaagt
    15241 acacgttaga attatagaag gaaaaagaga aagaatacaa gtattcgaag gtgtagtatt
    15301 aaagagacaa ggtggaggag caagagaaac tttcacagtt agaaaaatgt ctttcaatgt
    15361 tggtgtagaa agaactttcc cagttcactc tccaaaaata gaaaaaatag aagttactag
    15421 aaaaggtaaa gtaagaagag ctaaactaaa ctacttaaga ggtagagtag gtaaagctgc
    15481 taagataaaa gaagctagaa ataaataatt aaaaacttta cttataaatg gggggctgat
    15541 ttatcagtcc tctttctatt ttaatgaaaa ttacagcaaa taattatact aaaaataaat
    15601 agaaatattt gttgaaaata tacattattt atctatgaat ttataacttt taaaatgaaa
    15661 aataaaattg gtaaatattg cattgtattt tgtaacaata ttaaaaataa gagtacagta
    15721 ttttgtaaag tatgacgtta aaaagatgac aatattatag tttgtgaaga tatatttttt
    15781 tagtgaaatt aggatataat aatataatat ttaataagga gtgatacata tgtcaaatga
    15841 atatgaagag tatcttatgg atgacaatct acatataaac tggtatccag gtcatatgaa
    15901 aaaaactaag gagttagtaa aaaacaactt aaaattgatt gatgtagtaa ttgaactttt
    15961 ggatgctaga ataccgttta gtagtaaaaa tccagatata gacaggcttg taggagataa
    16021 gccaagagtt gttgtactta ataagagtga catggcagat aaggataaat tgaatcaatg
    16081 gattgaatac tataaaaaaa ttaatataaa agctatacct gtagatacaa taaaaggtgt
    16141 tggtataaat aagataatcg aagaatgtaa gaatgtaact agagaaaaaa tgagttcttt
    16201 aaaagataaa ggtagaaaag aaagagctat acgaataatg atagttgggg ttccaaatgt
    16261 tggtaaatct tctcttataa acaaattaac aggtagaaaa agtacgcaaa ctggagataa
    16321 accaggagta acaaaaggga aacaatgggt tagattaaag ggaaatcttg aacttttaga
    16381 tacacctgga atactttggc ctaagtttga agaccaagaa gttgcattaa atttagcatt
    16441 tagcagagct ataaaggatg agattttaga tactgagact ttggctttaa aacttataga
    16501 aaaacttatg aaaatagaac ctgagaagtt gaaagccaga tataagctag actgtctagg
    16561 agaaactcca attgaaacta tggatatgat tggtcataaa agagggttta taacaggtaa
    16621 aaaagaacta gattatacac gtatagccac aactgtattg aatgaattta gagacgggaa
    16681 aataggaaat ataacattgg aaattccaga aaacgttaaa agataaattt taaaacaaaa
    16741 tcaaaaattt aatgttaaaa atttaaaaaa gcccttccag aaaggctttt ttattttttt
    16801 gaaatataga caagtatttc tgtataaaag tataaattag gttagaaaac ctttaaaaat
    16861 attaatttaa gacaaatata tctaatattt tgaaaattaa aatgagtgtg attatttaaa
    16921 atcttggcat attgacttgc ttgtttcgta taatatataa taagcacaaa taaatacaat
    16981 atattaaaaa tttaatttat ttaattttat taatttaata atgagttctt attgtttaat
    17041 ttaacttatt tatgcaaacg taaacaatcg agatatttta ttaatttaat aaggttaaaa
    17101 agggggattt tataatgggt aagaccaagg atatcatagt atttggattt gcgttatttg
    17161 caatgttctt tggagcaggt aacttaatat ttccacctta cttgggaata attacaggtc
    17221 cagaatggtt aattgccttc ttaggattta catttgctga tgctggattg gcacttctag
    17281 cagtaatggc tacagctaaa ttcgatggaa acgtagttga aatgtttaaa agatgtggta
    17341 tgaaattagg gattcttata ggttgtgcag atattttatg tataggacca ttcttagcta
    17401 taccaagaac tggtgcaaca acttatgaaa tgggtataat gcctttattt ggaacttcaa
    17461 ttccagtgtt attattctgt atactttttt ttgcgatttc atatgtacta acaataaaac
    17521 cttctaaggt cgtagatata gttggacagt ttttaactcc agctcttcta atagctttag
    17581 catttataat tataaaaggt attatatcac ctcttggaga tatagtagat aaacctatga
    17641 tacctaatgt atttgcagaa ggtataggtc aaggatatca gacaatggat gcttttgcag
    17701 caatagcact tgcatcagta ctaatagtat ctttaaatga taaaggatat tctactatta
    17761 gtgacaagtt aaaaatgatt ggtaaagctg gtgttcttgc ttgtggagga ttagctctag
    17821 tttatggagg attatgtttc cttggggcaa ctgtatcaac aatgtatgga acagatgcag
    17881 tacaatcaca agtaatagta aatataactg aagggttact tggaaatgtt gggaaagtga
    17941 ttttagcagt agtagtttca ttagcatgtt tgacaacatc tataggtctt acatctgcta
    18001 caggtcaata tttctctaga ctcacaaaag gaaagttgag ttatgaaaaa atagtattag
    18061 ctgtatctgt attcagtgca gtagtagcat cttttggtgt tggaactata ataaagatag
    18121 catctcctat actaagtata gtttatccac catcaattgt tttaataatt ttagctttct
    18181 tcaatgaaaa aattaagaat gataatgtgt acaaaggagc tgtatatatg tcattgcttg
    18241 taagtatact aacagttata tctagttatg gagtagctgt tccagtagta aattctttac
    18301 ctcttcattc attaggattt aactgggtgg tgccagttat aatagctgga ataattggta
    18361 attttatacc atcaaagagt caatctaaca cacttggaac aaactaagtt ttgtttaat
//
LOCUS       DBGJFK010000080        18315 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.080, whole genome shotgun sequence.
ACCESSION   DBGJFK010000080 DBGJFK010000000
VERSION     DBGJFK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.080"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            105..989
                     /locus_tag="ACOIAP_003052"
     CDS             105..989
                     /locus_tag="ACOIAP_003052"
                     /inference="COORDINATES: protein motif:HMM:NF012376.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGZ2639929.1"
                     /translation="MVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDE
                     MTQWYKEWKNIRDNNSGKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLL
                     DAVIEDFEQVTISVLSANIYKQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKG
                     LENVNLQEQFQYKGKLYANDLVEDAKKWVKIMKKKKPDIIVAVVHSGEEPKNPKHPGN
                     RIKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNK
                     EKGSWIINDKFSKTIEVE"
     gene            1391..3295
                     /locus_tag="ACOIAP_003053"
     CDS             1391..3295
                     /locus_tag="ACOIAP_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGZ2639930.1"
                     /translation="MKIKFIIVVSIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LVSYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLLRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNDIPLVSANVYEQSGEN
                     YVNPYVMKNINTDKGVVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKI
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNIKEMTKWAKEW
                     QYNENKGIHKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEENLSSSSLSKNSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
     gene            3660..4439
                     /locus_tag="ACOIAP_003054"
     CDS             3660..4439
                     /locus_tag="ACOIAP_003054"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGZ2639931.1"
                     /translation="MSYKNIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKVFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIINISSQASFQPLPYQNIYSSTKAFVRNY
                     TRALNVELKSKGINAITVCPGWMSTNLFKRGIVVTEKGTKHFPGIVSPDVVAKKALKD
                     TKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(5391..6209)
                     /locus_tag="ACOIAP_003055"
     CDS             complement(5391..6209)
                     /locus_tag="ACOIAP_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2639932.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IESTIKRIGGNDIMKNYDVTIKNFASKYMMTLRMVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPRHSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGTWISDNDYDVDGPMFNIYHVSPGNDNNPDNWVTEVCFPVKKK"
     gene            6377..6958
                     /locus_tag="ACOIAP_003056"
     CDS             6377..6958
                     /locus_tag="ACOIAP_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2639933.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCIANGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEGVDVR"
     gene            6955..7149
                     /locus_tag="ACOIAP_003057"
     CDS             6955..7149
                     /locus_tag="ACOIAP_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639934.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(7313..9055)
                     /locus_tag="ACOIAP_003058"
     CDS             complement(7313..9055)
                     /locus_tag="ACOIAP_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HGZ2639935.1"
                     /translation="MVKSKKKIFVSLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSEEFYSNEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLSKSTVSIDGIEIDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDICEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLDDINKLFFDLEEEYGVSNNILKEKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQGDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            9484..10860
                     /locus_tag="ACOIAP_003059"
     CDS             9484..10860
                     /locus_tag="ACOIAP_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HGZ2639936.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSRGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVGKRRFSKLNVHSKVVLFSTATLILVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPATIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            11160..11831
                     /locus_tag="ACOIAP_003060"
     CDS             11160..11831
                     /locus_tag="ACOIAP_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGZ2639937.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            12018..12815
                     /locus_tag="ACOIAP_003061"
     CDS             12018..12815
                     /locus_tag="ACOIAP_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGZ2639938.1"
                     /translation="MITNINSKDNEKLKYTKALLKSKNRNKESKFIIEGYRIVVLALE
                     CMANLDYVFINEDFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVEAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIINASQDETVDMLKSLDFNIVSSYLNTDNFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKSLI"
     misc_binding    13076..13310
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13360..14379
                     /gene="pheS"
                     /locus_tag="ACOIAP_003062"
     CDS             13360..14379
                     /gene="pheS"
                     /locus_tag="ACOIAP_003062"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGZ2639939.1"
                     /translation="MQEKLLALREVALAEIKEAQSIESVESLRVKYLGKKGDITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            14396..16789
                     /gene="pheT"
                     /locus_tag="ACOIAP_003063"
     CDS             14396..16789
                     /gene="pheT"
                     /locus_tag="ACOIAP_003063"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGZ2639940.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     NDALIDFELTSNRPDCKCMLGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRTAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITDD
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVADDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNVKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFVLKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEEVAKVHDKILSELSEKLNANLRSN"
     gene            16814..17404
                     /gene="zapA"
                     /locus_tag="ACOIAP_003064"
     CDS             16814..17404
                     /gene="zapA"
                     /locus_tag="ACOIAP_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGZ2639941.1"
                     /translation="MNKVMVKIHGVEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAEAKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDVKNVE"
     gene            17603..18286
                     /locus_tag="ACOIAP_003065"
     CDS             17603..18286
                     /locus_tag="ACOIAP_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGZ2639942.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKAKIHWRQVIIIIEMI
                     TILIVSFVPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFIFGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT         7079 a         2057 c         3180 g         5999 t
ORIGIN      
        1 ggggatggcc tgtggagaat tagtaagaca tattttagta tgcaaaattc tatgaaacag
       61 gaaccctgtg actttagtca tgggaggttc agaaggaagt aagtatagtt gctactgcag
      121 atttacattc acatttttct gataaattaa cagtcgacct tgttaatgaa cgaagcaacc
      181 caattgaacc tgttgtagta gatgcaggtg atttcttaga ccctcaaaca gatgaaatga
      241 ctcaatggta taaagagtgg aaaaatataa gagataataa tagtggtaaa acgattagta
      301 gatgcccaat ggtcatggat atgaatcagg gaatgtatga tgcagtagta cttggaaatc
      361 atgagtttgt atctgaaaaa gatgagtttt ggtcagatga gcgtctttta gatgctgtta
      421 tagaggattt tgaacaggtg acaatttctg tgttatcagc aaatatatat aagcaatctg
      481 gtaaaaatta tgttaaacca tatattataa aagatgtaga gacgagtgaa ggtaatgtaa
      541 aagtaggaat attagggctt actataaaag aagtaggtaa aggtcttgaa aatgtaaatt
      601 tacaagagca atttcaatat aaggggaaat tgtatgcaaa tgatttagta gaagatgcaa
      661 agaaatgggt aaaaattatg aaaaagaaaa aaccagatat aatagttgca gttgtacatt
      721 caggagaaga gcctaaaaat ccaaaacatc caggaaatag aataaaggag ctagcaacta
      781 cagtagatgg tattgatgcg attgttgcta gtcatactca tgaaaaaata gatgaacatg
      841 aatataaaaa taagtctgga gagaaagtta tagtgacaca accaggtgag catggtaaat
      901 attattctaa aattactttt aaagtaaata aagaaaaggg ttcatggatt attaatgata
      961 aattcagtaa aacaatcgag gttgaataac tttataaaat ctatagataa aataaattat
     1021 ctgatattga cataatatac aagataaagt ttccaatatt agtacagagc ataaggtaaa
     1081 atattctaat aataagagaa taaacaagat aaataaaaat atttcaacat ataatatata
     1141 gtatgaacat attatactac tccttacttt ataatttgaa catgttagaa taagtcttac
     1201 ttgacaattt tagtgtatta gagtaagtat tattttgcca ataaaaaaca ttgagaacta
     1261 tatgtagatt tgcttaaaaa ggaatttaca tatagttctt ttcgtataat aaatagtaca
     1321 atcttatgtg gtaaagataa cgcgtgatat taaattttat tatcatccaa aatctaagga
     1381 ggagtctttt atgaaaataa aatttattat agtagtatca ataatatttt taatagtatt
     1441 acttgtaggg tgtcaaagta ctaaagatac agaaataaat gtactcgcta caagtgattt
     1501 acattcaatt attccagata atttagtctc ttatgtagag gaagagagaa aatatgatga
     1561 gaatctactt atggtagacg caggagattt ttttgacatg caaagtggtg agatgaacaa
     1621 gtggtttact ggtcaaaaac tattaagatt taaagatggg ataccagagt acaaaaaaat
     1681 agccgaacca cgtgaaggtg aagttccatt agctaaaaaa atggcaaagc tgaaatatga
     1741 tgcagttaca tttgggaatc atgaatttgt atctaatgac aagcagagcc ttgataaatt
     1801 agtttctgat tttaaaaata acgatatacc attagtatca gcaaacgtat atgaacaatc
     1861 tggggaaaac tatgtaaatc catatgtaat gaaaaatata aatactgaca agggagttgt
     1921 aaaggttggt atacttggtt tgactataaa agaagtaggg gaacgttcaa ggtttaaaag
     1981 ttttgaacaa gataaaaagg ctagagaact tggggagcaa cctcaataca aagggaaatt
     2041 atatgcgaat gatttggtag aagatgcaaa taagtgggta aaggttatgg aaaaaaaaga
     2101 aaagccagat ataatagttg ctattgtaca ttcaggtgaa gagccaaaaa atcctaaaaa
     2161 tccaggaaat agaataaaag aacttgcaac tactgtagag gggatagatg ctattgtagc
     2221 aggtcataca catgaaaaaa tagaacagca tacatataaa aataattctg gtgaagaagt
     2281 aatagtaaca cagcctggag ctcatggtaa tagtatatca aagattaatt ttaagttgga
     2341 taagaagaat gataagtggt ttataaaaga taaatatagt gaattaaaaa tttttggaaa
     2401 ggaagtaaat ataattacaa cctctggtct gaatccaaaa ttttcagatg aaatggcagt
     2461 taatttgttt aatgaaagag atagggatgt tcaacctata tttatagata ctggagattt
     2521 tttaaatact aatataaaag aaatgactaa atgggctaaa gagtggcaat acaatgaaaa
     2581 taaaggtata cataaaaaaa taaatgaatg gccaattgta tatcttggtt atgatgctgt
     2641 agtacttggt agtcatgaat ttacagaaga taaagagact tttgaggaaa aaaaatctac
     2701 tttggattat attatagaaa actttgaaga aatgaagata ccagtattat cagctaatat
     2761 atatgatgaa tctggagaaa attatgtaaa accttatata attcataatg tagaaactag
     2821 ggaaggaaat ataaaggttg gagtattagg tcttactact actgataagg atgaagaaaa
     2881 cttaagtagc tcaagcttaa gcaaaaactc aaagacttcg aaaattcctg aagaaacagg
     2941 aaagttatat accaacaatc tagtaaaaga tgcaagcgaa tgggtaaaag ttatgcaaaa
     3001 ggaaagtcct gatgtgattg ttgcagttgt acattcagat aataatagta ctctaaaaaa
     3061 tccaagtagt gaagtaaaaa aacttgcaat gtcagtagat ggaatagatg ctattgttgt
     3121 aggtcatacg aaaaataagg tagaagaaca tatttacaag aataagtctg gggatgaggt
     3181 catagtaaca caatctggag aagattgtta ttcaaaaata agtcttgaac taagaaaaga
     3241 aaatggcaag tggaatatca taaacaaata tagtaaagca ataaaaatga agtgaattta
     3301 ttgatatata aaccattatt aacactgatt tttataatat ttaacactac tttttatact
     3361 ataattaaca ctgattctat aatatcatta acattacttt tatactataa ttaacactga
     3421 ttctatagta ttattaacac tactttttat actataatta acactgattc tataatatca
     3481 ttaatattac ttttatacta taattaacac tgattctata atattattaa cattacttct
     3541 tatgctatat aacaattatt gaaaatgata tgaatataac atctgaatag agggtgtttt
     3601 atttgtaaaa aataagttta cagtttgagc gtataaactt atggtaaagg agaataatta
     3661 tgagttataa gaatattgca attataacag gtgctaatag tggttttggt aaagagtttc
     3721 taaaattatt aataaatgaa gaagaaataa cagaaatatg ggcagttgca agaaacaagg
     3781 cgagattaaa tcaattagta gatgaatttg gaagtaaggt aaaagttttt tcaaaagact
     3841 tatcaaagat agaagaagta aaagaaattg gtacattttt aagtaaagaa aatgtatgta
     3901 taaaatacct tataaataat gctggttttg caaagttctg ttcatacaat gatttaagta
     3961 tagatgaatc tattaatatg attgatttaa atattagtgc tgttgtagca ttggggctta
     4021 tatgtattcc atatatgcaa aagggaagtc atatcataaa tatttcttca caagcatcat
     4081 tccaaccatt gccataccaa aatatttata gttcaactaa agcatttgta agaaattata
     4141 caagagcatt aaatgttgag cttaaaagta aagggataaa tgcaattact gtatgcccag
     4201 gttggatgag tacaaatcta tttaagagag gtatagttgt aactgaaaaa ggaacaaaac
     4261 atttcccagg catagtgtct ccagacgttg ttgctaaaaa agcattgaag gacacaaaga
     4321 agaataagga tatttctgta tatggtataa atacaaaatc cagtcattta ctagcaaaac
     4381 tattgccaca aaagatgatg atgaaggttt ggttaatgca acaacatatt aaggaataag
     4441 agttttggta attaagtatc agttagagat tcaatctgtt acaaattatg agaatttttg
     4501 ttgagtaaat aataattgtg acaaaacggc ttatctagtg ctgataagcc gtctacaatg
     4561 tatataaaat atatttttaa tttcaaagtt attacaccac cttcttaaaa tattagatta
     4621 tataaataat ctacaatcac aactgattaa caaaattatg agttaataaa ttatatcaca
     4681 tgcaaatatg aaagaatagt atgaaatttt tataaacata tattaaatgt ttctcaatga
     4741 aattgacttt gtatatgaac tgaatgactt attcaatatg gataagacat ttttcttgta
     4801 ataagatatg attgtcctat aaggtttatg taattttgat ataatatatt gattaacagc
     4861 atacatgtta ttggtgaaca tatttctata gaatggaata tataattttt tatatttatc
     4921 attgtatcat tgtctaaaga aagttaaaaa gagtagagca caaaggaatt atttgtactt
     4981 tactctttta ttgttttgtt aaaaatacta atttatatta gtgattaaaa tatatttaac
     5041 tagagtataa ggatagtata taatcttata attgatttat ctgacaaatt aagataatat
     5101 actaatcaaa ttctggttat ttaaacataa aatcataatt gatttatctg acaaattgag
     5161 ataatatcct aattaaattg taggtattta aacataacat tataaataat ttatctgaca
     5221 aattaagata atatactaat caaattctag tcatttaaac ataatatcac aagtgattta
     5281 tctggcaaat taagataata tcctaattaa attgtaggta tttatacata acactaaaag
     5341 taatttgtct aacaaattaa aatattatcc aattaatata taagataaaa ttacttcttt
     5401 ttaactggga agcatacctc tgttacccaa ttatcaggat tattatcatt accaggactt
     5461 acatgataaa tattaaacat aggaccatcc acatcgtagt cattatctga tatccaagta
     5521 ccaatagctt cacaagcatc tgcaacttga ttgaaatttc cattaacaat tgcagttgca
     5581 gcagtcacac ttggaacagt cttaaattta acatgctcag tatctttata ctttccagat
     5641 acagcaactt gtacttcaac atctacataa tcttctttat atccagtatc ataaaagact
     5701 gccttagaat gtcttggtgg ttcaatttga acattctggt cttttgtctc taaaaatgct
     5761 tgatgccata acattccttc gtcttgataa gttggtataa ccattctaag tgtcatcata
     5821 tattttgatg caaaattctt tatagttaca tcataatttt tcataatatc atttcctcca
     5881 attcttttaa tagtactttc tatttttaat agttttttct gtgtatcttc taattgttct
     5941 tttacttgag aatggtggat atttagatat tttataagac tttctttatc gttatattct
     6001 gtcaaaattt cttttataga atacaagcca aagcccatat cttttagtgc atggattctg
     6061 tttgttgtag aaagttggtc tgcgctatag tatctatatc cattagtttt attcgtatga
     6121 gaaggagtta aaagccctat ttcgtcataa tgacgtaaca tacgaatact aattttactt
     6181 agttttgaaa aatcgcctat cttaaacatg tttttgtctc ctttataaag gtacttttag
     6241 cttaatatta atataaacca tatcataatg ttagagtcaa ctaaaattat aattaaatta
     6301 tattgacata tgatgaaaaa aatattatac tgaacatgtt cagaactaaa aatgttaatt
     6361 gttttggagg tccattatga aaagtaatga taaagatgct agagaacgta taattgaagt
     6421 tacattgaat cttttaaatg aagtagatga tattgaagag attacagtta gaaaaattgc
     6481 tgagcgtgca aatgttggag ttggtttaat aaattatcat tttaaaacaa aggataattt
     6541 gttgagtact gccataggag atgtgatgtc aaatataata gcagagctat atgacgatag
     6601 tgtatatact ctaagaccta ttgaagattt gaaaaattta ttaaaaaaat tgtgtgatac
     6661 tggattacat tatgaaaaag tgcttccttt tgtgttgaat caatgtatag ccaatggaga
     6721 tatgcaagca gaacttgata ttgtccctat gcttcgtaaa atttttggaa ataaaaaaga
     6781 tgaaatgagt ctaagaatta ttgccctgca aattatttta ccaatacaga tttctgcttt
     6841 atctacagaa tcatttcagt tatacagtgg tataaatata aagaataaat atgagcgaga
     6901 taaatttatt gatattttaa tagaaaatat tattggagag ggtgttgatg taagatgaaa
     6961 attataacta ttggttcaag tcttatcact gttttacttt ttctttcaac tatggtttgt
     7021 gggttctgga ttaagaataa taaggtaaca gatgcaagtt ctattaagtt ccatatgaat
     7081 agtgctattt ttacagggat atttttattg atttccacaa tccttttaat tatatatata
     7141 aaaaaataat aatattatta atagataaag tatcagaaat tataaagaca agagtcttaa
     7201 aaatttctga tactttacca tataatttta ttaaacatta attgtgtgtg aaaaaatatc
     7261 acttatttca atctaatgct aaatcttaag agtaagcata aagtattaaa aattaagaag
     7321 cattttttag ttcaagtgga ttatctatac caaaataatc atataaagta gagcttattt
     7381 cctctaaatt tccatcttgg aaaggtaatt gtaaattcac cttttctacc acatccttaa
     7441 atccagcatc agtattttga tttaaaaaat ccatatatac atcaacagct tttctgtaat
     7501 caccttgtga taattgccat atctgaagtg atacatcaga tgcaagacca taactcaagt
     7561 aataaaaagg aacttggaag ttatgagata caagtatcca aaaaggagca tttttttctt
     7621 taagtatatt attggaaact ccatattctt cttccaaatc aaaaaacaat ttattgatat
     7681 catctagact catatatgga ttcttatata taatttcttg aaattcatca taaagacaag
     7741 catcaataat agtgtttaaa acaatcgata agtgttcttt ttttatagct tcagattgtt
     7801 tcccaaaaaa atcatcaaaa tatttgtaaa atagaatttc taaagatgtt gaatgaactt
     7861 cacatatatc tatacttggt tgcatcttat tatttaagtt aatactgttg tagtaattat
     7921 aaaaatgacc aaattcatgg gcaaaactag taacacctaa aaaagaatta tcccatgtat
     7981 taaataagaa aggagcttta tacttattta tataagtggt atatcctcca ggtgatttgt
     8041 tctttccaga agaataatcg tacaagtcat attttttcat atagtcaaag ctctctttta
     8101 gttttggaga tatatcttca agcaccttat caaactttct aaatgagcga tttttatata
     8161 ctttaatata aatagaagaa tcagaaggtt tagatgaaat ctctctatat aatggaacta
     8221 tgtaatcttt tacatcttgt ctaaattttt tagcttcctc ttgagaataa tctttgttta
     8281 ggttcatata ggcataatct atataatttt taaaaccttg cttacttgct atttcagttc
     8341 ttgtctgtat aagttctaag aatatgttac caaatatagg gttgtatttt tttaagtaat
     8401 ctgaataaat tttaacatat tcttcagggc taagatttgg tcttgacaag gcttcttcaa
     8461 agtctatttc tataccatct attgatactg tagatttaga taacaagtct tcatatttta
     8521 caactaggtc ttgttctttc ttaagtaaac cttcaacttc tttagaatta agttttccaa
     8581 tgttctttag ataattaaat gtatcttttc caagttcttt ttctaattct ttagagaatt
     8641 tagaagttac aaatctatct tgaaagtctt tgtatgacat gtcaacatct actgatttac
     8701 tcataagata cttgtattca ttagagtaaa attcttctga tgaatctatg ttatttctaa
     8761 tttttgctat agtaagtgta ctgtaaaaat cttgataaat tttatcaact tcattaaata
     8821 aatttaattg ttctttagct gttttagctg ttaaaagttt gtcgttacat ttgttaatgt
     8881 tttcgcaaat tgactgtata ttaggacgct tatattccat tttttcaaaa ggaatagttc
     8941 ctctaacaga atcttttttt gtatcattag tataatttct tatgtatgat gcaaatataa
     9001 taaaaactgc aattaaaatt agagaaacaa atattttctt cttggattta accataaaaa
     9061 tcctccaatc atggatatag ttattaatta ttttactata ttaaatataa aaaatgcatg
     9121 ttaagaaaat ttaacataag gatatggata agattataaa taatataaaa aatttaactt
     9181 caaaaaagta tatgaaattt atactagtaa aatgataaat aaattctaag tacaaaatag
     9241 taaaagttat gatagtttta gacctattat atttaaaaaa tatagatgtt tttggtgcaa
     9301 tttaaattaa aagatatata caaaaattta aaatattcca aacagaaatt ataaaaatta
     9361 ctatcattgt ctttatacaa tatttatact ataatagaat aataatttag aggaaagctc
     9421 taaaaataaa caaattaagg gtcttaacag tagtgatttt atgttaagga ggtataaaga
     9481 aagttgaaaa caatagttag aagacttatt ctctacgcag atggaatgcg tcctactcaa
     9541 ataatggtat ctgggtttgc tgcgattatt gtaatcggag cattgttgtt aacactcccg
     9601 atagcgtcgc agagtggaga gagtataggc ttattaaatg ctttatttac ggctacttca
     9661 gcggtttgtg ttactggtct agttatggta gatacagcaa cttattggag tttatttgga
     9721 cagatagtta taataacatt gatacaaatt ggtggtcttg gatttatgac cgtagccaca
     9781 atgttttcac ttatggcacg aaaaaaaata caactaagag aaagattatt aatacaggag
     9841 tcattaaatc aagctgattt atcggggctt gtaagactta caagatttgt attaataata
     9901 accataacaa tagagggaat aggtgcacta gttttatcaa ctgtctttat tccacaattt
     9961 ggtttgtcta gagggatatg gtatagtgta tttcacgcaa tatcagcgtt ttgtaatgcc
    10021 ggatttgact tgatgggcag tgtaagtggt ccatttacat cgttaaattc ttatgtaaac
    10081 aactttacag tatcaatgac tgtttgtgca cttatagtgc ttggagggct aggattccct
    10141 gttgtacttg atattgtagg aaaaagaaga ttttcaaaat taaatgtgca ttctaaggtt
    10201 gtattgtttt caactgcgac acttatttta gtgggtgcat tatttatttt tcttatagaa
    10261 tttaatcaaa aagctactat ggcggacttg cctttaaagg gaaaagtact atcagcaata
    10321 tttcaatcag taacagcaag aactgctggt tttaatacgc ttgatttagc cactttacga
    10381 gaaagtagtg tatttgtaat gataattttg atgtttattg gagcatcacc tgcatcaact
    10441 ggtggaggta taaaaacaac tacactagct gttttaatca ttacagttag aagttttcta
    10501 tcaggaaagt cagatataga agcttttgaa agaagattag caccagcaac tataaaaaaa
    10561 tctctgggta tatttgtaat tagtatatca gcagttattt ttggaacatt gattatttca
    10621 ataactcaac ctaattttac attagttcaa tcggcttttg aggttacatc agcacttgct
    10681 acagttggtt caagtttagc tggaactcca aacttaaatg ctttaggtaa gattataata
    10741 ataatcttta tgtttatggg tagagttggt tctcttactt tatttatggc tatactttct
    10801 ggtggtagaa gaaagagcca accaatcaga tatgcagaag gtaaaattat ggttggttaa
    10861 tttaccaagg agtagtataa atttataatg ggtttagagt agtaatgtaa atctgttgat
    10921 aaaataaatg agcctagatg taattatatg aagaaataaa atcgactaat gagcaaaatt
    10981 aattaatgaa ataaaaaata gtgaaataaa aaatagtgaa ataaaataca aataaaagat
    11041 aaatcaaaat taaattaatc tatgtatata aaattataga ttgtatacaa gttttgtatg
    11101 cataaccgat taatttaata gatattatat aaattgtgta ttagggagga agtttcgaga
    11161 tgaagcaata tatagtcatt gggtgtggga gatttggaag ttcagttgcg tctactatgc
    11221 atcttttagg acatcaagta atggcaatag acaaaaatga agattcagtt caaagtatat
    11281 ctgacaaggt aacccattca cttatagtgg atgttactga tgagcaagcg ttaaggtcat
    11341 taggtttagg taactttgat gtagcagtag ttgcaatagg ttctgatata agggcatcta
    11401 taatggcgac tcttatagcc aaagaaatgg gtgtagagtt gataatatgt aaggcaaagg
    11461 atgaattaca agctaaagta ctttataaaa ttggcgcaga tagagttgta tttccagaaa
    11521 gagatatggg agtaagagtt gcacacaatt tagtttcaga taatatatta gaccatattg
    11581 aacttgaccc agagtattca attgttgaaa tcgtaactcc aaatagttgg gttggcaaga
    11641 cacttataga gcttgaatta agagctagat atgagataac tgtacttgct ataaaaacag
    11701 gtaaaaatat aaatgttaca ccttctccag atgaggaact tacagccgga agtattctag
    11761 ttataattgg tcaaaatact agtataacag ctataacatc tggaaataag gggataatta
    11821 gaagaagata atttattatt taatatatat ttaattgcaa tgaaagtaga tagtatcata
    11881 taattatgaa tagttatatg atactatttt tatttaatca aaagtaggat ttagatgtaa
    11941 gattaggtaa agagtatttt aagttaaaaa aggagtaagg aggttgtgct aatatagaaa
    12001 tttagcattt agataaaatg attacgaata taaacagtaa ggataatgaa aaattaaagt
    12061 atacgaaagc actgttaaaa tcaaaaaaca ggaataaaga atcaaagttc ataatagaag
    12121 gttacagaat agtagtactt gcacttgaat gtatggcaaa tcttgattat gtatttatca
    12181 atgaagattt tgaaaataag aaagaacatg taaaactatt agaagattta gataaaaaaa
    12241 acacaaagat atataagact actaataaaa actttaaaga attagtggat acagaaaata
    12301 ctcaaggtat aataggtgta gtttcattta agaaaaaaaa attaagtgaa agtataaata
    12361 aaaaagataa atttgtattg attttagaca gaatacaaga cccaggaaat atggggacta
    12421 taataaggac tgctgattct gctggggtag aggccataat agcactaaag ggatgtgtcg
    12481 atatatacaa cccaaaagta attaggtcta ctatgggttc tatttttgat atgaatataa
    12541 ttaatgcttc acaagatgaa actgtggaca tgcttaaatc attggatttt aatatagttt
    12601 caagttactt aaatacagat aatttttatg acaaaataga ttatggttca aaggtagcat
    12661 tggtgatagg aaatgaagca aatggaataa atgaagaact tgtatcaaag tctgatattt
    12721 tggttaagat acctatatat ggtaaagctg agtcattaaa tgctgcgata agctctgcta
    12781 tactgatgta tgaaataaaa aaatccttaa tttaatgtat tgtaataaat ataatgtcat
    12841 gttataatct tgaattaaat agtagagtat caaaaatagt caatatatat taaaaaaata
    12901 gttcaattaa ttatatatta gatgtgtatc atataaaaaa tgattgaatc aattatatat
    12961 tagatgtata ttatataaag aaataattga attaattata tattagaggt atattaaaaa
    13021 tagtcacata atttgaatgg aaatgatata atactaaaat aaacaatatc atattgtaaa
    13081 tgcaatgaaa gaggaaagta ttttgattaa acttagtaaa gagataaaca cctaggctgg
    13141 gagtgttttc taagaggtca cgagaagttc cctctggagt aacagagctg aaattttata
    13201 gtaggctttg acgtcaaaaa cgcgttaagt ttgttagagg tggtttgatg atttttaaat
    13261 tgttaaacta ctagggtggt accgcgaaac tatagccttt cgtccctaga cagggattga
    13321 agggcttttt ttatacaaaa aaacgaaagg gtgatatgtg tgcaagaaaa attacttgct
    13381 ttacgtgaag tagctttggc tgaaataaaa gaggcacaaa gcatagaaag tgtagaaagt
    13441 ttaagagtta agtacttagg aaaaaaaggt gatataactg ccatacttaa agaaatgggt
    13501 aaattatcag ccgaggaaag accagtagtt ggtaaggttg ccaatgaggt aagagaaaat
    13561 attgaactta gcataaattc taaaaaagaa gaaataaatg ctattgaaaa agaaagaaaa
    13621 ttaaaagaag aagtaataga tgttactcaa ccaggaaaag ttttaaaggt tggaaagaaa
    13681 catccaataa ctcaaattat agatgaagta acagatatat ttatcggaat gggattctct
    13741 atagcagaag gtccagaagt tgagactgtt gaaaacaact ttgatgcttt aaatgctcct
    13801 aaagaccatc catcaagaga tatgagcgac acattctata tcaatgatgg ggtattactt
    13861 agaactcaaa catctccagt tcaagtaaga actatgagaa gtcaagaatt accaataaaa
    13921 gtaattgcac caggtagatg ttttaggtca gattcaccag atgccacaca ctcaccaatg
    13981 ttccatcaga tagaagggct tgttgttgga aaagatgtta ctatggcaga atttaaagga
    14041 actatggata tcttcgttga aaaattgttt ggttctgata tcaaaactaa gtttagacct
    14101 cataacttcc catttacaga gccaagtgca gaggttgacg ttacttgttt caaatgtggt
    14161 ggtaaaggtt gcccaatgtg taaatatgaa ggttggatag aaatattagg ttcaggtatg
    14221 gttcatccaa acgtgcttag aaattgtgga atagacccag aagtttatag cggatttgca
    14281 tttggagttg gggttgaaag acttgcaatg cttaaatacg aaatagatga tattagatta
    14341 ttattcgaaa atgatatgag attcttaaat caattttaat taggagggta tgtagatgtt
    14401 agtatcttta aaatggctta gagactatgt tgatatagac atggatgtaa aagagttcgc
    14461 tgataaaatg acaatgacag gaactaaagt tgagacaata gattattatg gtgaagaaat
    14521 agaaaatata ttggttggaa agattttaga aataaagcaa catccaaatg ctgataagtt
    14581 ggttgtaact aaagtagata ttggagataa agttgttcaa atagttacag gagctacaaa
    14641 tatatcagaa ggagattata ttccagtagc tgtaaatggt tctaaattac ctggaggagt
    14701 ggaaatcaaa cagactgatt ttagaggtga attatcagat ggtatgatgt gttcagcagc
    14761 tgaactaggt atagatgaac attacattga agagtataaa agaggtggta tatatatttt
    14821 agaccacgaa gattcttatg aattaggaaa agatataaaa gatgttttag gattaaatga
    14881 cgctttaata gattttgaat taacttcaaa cagacctgat tgtaaatgta tgctgggtat
    14941 agctagagaa gcagctgcaa ctataggaac aaaagtaaaa tatcctgaaa ttgaagtaaa
    15001 agaaagtgat gaagagatag acttcaaagt tgagatagac aatccagatt tatgtagaag
    15061 atatgttgct agaatggtta cagatgtaaa aatagaacct tctccatatt ggatgcaaag
    15121 aagacttaca gaagcaggtg taagacctat aagtaacata gtcgatataa caaacttcgt
    15181 aatgttagag cttggtcaac cacttcatgc ttttgatata aatcaagtag aaactggaag
    15241 aatagtagta agaactgcta aagatggaga aaaacttgta acattagatg atgttgagag
    15301 aacattagac aaagatatgt tagttataac aaatggagaa aaatcacttg gtttagctgg
    15361 tgtaatgggt ggtgctaact cagaaataac tgatgataca aagactgtac tttttgaaag
    15421 tgccaatttc aaaccagaaa acataagaat gacagctaaa aaagttggta ttaggtcaga
    15481 agcatcttca agaaatgaaa aagacttaga ccctaatctt gcagagatag cagcaaatag
    15541 agctgcacaa cttgttgaaa tgttaggagc aggaaaagtt ttaaaaggtg ttgtagatgt
    15601 atatccaaat aaaccagaac ctaaaaaatt ggtagtaaat cctcaaagaa ttaaccattt
    15661 attaggtgta gatgtaccaa tggagcagtt tgtaggaatc ttagaatcat tagaatttaa
    15721 atgtaattta gtagctgatg ataaattaga aatagatgta ccaagcttta gaacagatat
    15781 ggaacaagaa gctgatgtat gggaagaaat agctagaatt tatggatttg agaatatacc
    15841 atctgtacaa ttagaaggaa atacgacagc aggaatcaaa acttcaaaac aaaagtttat
    15901 ggatgcttta aaagataatt caactgctgt aggactaaat gaaatattaa catattcatt
    15961 tgtaagccct aaaggagtag ataagataag agtaccagaa ggtaatgtga agagaaattt
    16021 tgttaagcta cttaatccat taggagaaga aacttctgta atgagaacta ctttaatacc
    16081 aaatatgtta gatgttttat caactaatgt atctcataaa atagaagaag tatctgcatt
    16141 tgagtgtgga catatattca tcccacaaga ttcagaatta cctaaggaag aaaatagaat
    16201 gtgtgtaggt atgtacggta aagatgttga tttctttgta ctaaaaggaa ctatagaaac
    16261 tatacttgta aatgtaggat ttaaaggtta tgaaattgaa cctcaagata ataatactac
    16321 cttccaccct ggtagatgtg ctaaaatagt gtataataat aaatatgtag gtacattagg
    16381 tgaattgcat ccagatgtta tagaaaacta caatctaggt caaagagttt atgtcgctga
    16441 aatagatatt gactttgtat ttgataattc tgatagaaca aagaattatg taccattacc
    16501 aaaatatcca tctacatcaa gagatatagc tcttattgtt aaagatgatg tatttgtaaa
    16561 acagatagaa gatataataa aggaaaatgg tcaaggatta gtagaaagct acaagttatt
    16621 tgatgtttac aaaggttctc aaatagaagc tggatacaag tcaattgcat attcaataac
    16681 ttatagaagt aaggataaaa ctctgactga tgaagaggta gctaaggtgc atgataagat
    16741 attaagtgaa ttaagcgaaa aattgaatgc taacttaaga tcaaattaac aactaatgtc
    16801 gggggaggtt aggatgaaca aagtaatggt taaaatccat ggcgttgaat atccaatggt
    16861 tggagacaaa tcagagaagt ttatgattag tattgctgat tttgtagaca aagaaatgga
    16921 taaaataaca cgtcaaaacc cgaaattgag cttatcagtt gctgcgatat tgactgcatt
    16981 aaatatatca gaccttttat ttgaatgttc agatgagaat gagaagttga ttaaagctaa
    17041 tgaagaattg agtaagaagg ttggagcatc taatgaagag cttcaattag aaatcaagtc
    17101 tttaaagctt acgatagcag aaaaagaagc agaaaatcgt gaagctgagg ctaagatgaa
    17161 agagttaatt gagattatag aaaataaaaa gcaagaaata ttcgaactta gtaatacgac
    17221 agaaggttct agggcggagt tagatgctta taaaaacaag attgaggagt taagtactca
    17281 acttgaagaa gcaaatgaaa gagctaccat agctgaaaat ttagcttctg agtttcaaaa
    17341 caaagcttat gatttacagc taaaatgtac agggttaaat aatgatgtaa aaaacgtgga
    17401 ataaattaaa agatttgctg tctcttgttt tttgagacag cttcttttaa tgtataaata
    17461 taaatgataa atataaataa atataaatga tgtataaata tagacaatat ttaaatataa
    17521 atgatttttt tatattaatg aaaaatagaa tctaaaatga ttttgatttt gtatctatca
    17581 ttagaaagtg agaggtttat atatgacaag caagagtcag atgtccgaat cattcttttt
    17641 atgttcttta ttggcaataa caggaggatt tttagatatt tatacttatg tggtaagagg
    17701 taaagtattt gctaatgcac aaactggaaa tatagttcta tttgggctta atatagcaga
    17761 aggtaatgta aaggaatcat tttattattt gattcctatt ttggcattta tgttaggcgt
    17821 atttatagct gagaagataa gaaagtattt tacaaacaat aaggcaaaga ttcattggcg
    17881 tcaggtcatc attataattg aaatgattac aatacttatt gtttcatttg ttcctagagg
    17941 aagatttaat atgtttgtaa atgttgccat ttcttttatt tgttcaatgc aagtggagag
    18001 ttttagaaag gtaaatggga atagttttgc aacgacaatg tgtactggaa atttaagaag
    18061 tgctacagaa accttatttc attatataca tactaagaat atttttatga taaaaaagag
    18121 tttacaatat tatgctatta ttatattctt tatatttgga gctattttag gaactttttt
    18181 tacaaaaatt ttcgtggaaa aatcaatact aatatgtttt tttattttgg cagtggtatt
    18241 tggaattatg tttatcaata aagatgattc atttaatgaa aattaacttt ctgtaaattt
    18301 acaaaaaaat gaagc
//
LOCUS       DBGJFK010000081        17983 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.081, whole genome shotgun sequence.
ACCESSION   DBGJFK010000081 DBGJFK010000000
VERSION     DBGJFK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.081"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            307..621
                     /locus_tag="ACOIAP_003066"
     CDS             307..621
                     /locus_tag="ACOIAP_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGZ2639943.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            637..1023
                     /locus_tag="ACOIAP_003067"
     CDS             637..1023
                     /locus_tag="ACOIAP_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGZ2639944.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1052..2437
                     /locus_tag="ACOIAP_003068"
     CDS             1052..2437
                     /locus_tag="ACOIAP_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGZ2639945.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2440..2592
                     /locus_tag="ACOIAP_003069"
     CDS             2440..2592
                     /locus_tag="ACOIAP_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2639946.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2615..3820
                     /gene="mobT"
                     /locus_tag="ACOIAP_003070"
     CDS             2615..3820
                     /gene="mobT"
                     /locus_tag="ACOIAP_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HGZ2639947.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            3863..4084
                     /locus_tag="ACOIAP_003071"
     CDS             3863..4084
                     /locus_tag="ACOIAP_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639948.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4201..4698
                     /locus_tag="ACOIAP_003072"
     CDS             4201..4698
                     /locus_tag="ACOIAP_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGZ2639949.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            4787..5179
                     /locus_tag="ACOIAP_003073"
     CDS             4787..5179
                     /locus_tag="ACOIAP_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2639950.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            5163..7610
                     /locus_tag="ACOIAP_003074"
     CDS             5163..7610
                     /locus_tag="ACOIAP_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2639951.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7613..9790
                     /locus_tag="ACOIAP_003075"
     CDS             7613..9790
                     /locus_tag="ACOIAP_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGZ2639952.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            9787..10788
                     /locus_tag="ACOIAP_003076"
     CDS             9787..10788
                     /locus_tag="ACOIAP_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HGZ2639953.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            10785..11717
                     /locus_tag="ACOIAP_003077"
     CDS             10785..11717
                     /locus_tag="ACOIAP_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2639954.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            11962..12078
                     /locus_tag="ACOIAP_003078"
     CDS             11962..12078
                     /locus_tag="ACOIAP_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HGZ2639955.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12094..14013
                     /gene="tet(M)"
                     /locus_tag="ACOIAP_003079"
     CDS             12094..14013
                     /gene="tet(M)"
                     /locus_tag="ACOIAP_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HGZ2639956.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNVCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14132..14299
                     /locus_tag="ACOIAP_003080"
     CDS             14132..14299
                     /locus_tag="ACOIAP_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HGZ2639957.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14359..14712)
                     /locus_tag="ACOIAP_003081"
     CDS             complement(14359..14712)
                     /locus_tag="ACOIAP_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639958.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15217..15639
                     /locus_tag="ACOIAP_003082"
     CDS             15217..15639
                     /locus_tag="ACOIAP_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGZ2639959.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15636..15866
                     /locus_tag="ACOIAP_003083"
     CDS             15636..15866
                     /locus_tag="ACOIAP_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2639960.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            complement(16092..16343)
                     /locus_tag="ACOIAP_003084"
     CDS             complement(16092..16343)
                     /locus_tag="ACOIAP_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639961.1"
                     /translation="MSVCFIKSSFPNHLFGFHKSCFTSNRTALAKLTGVPPLHGSHVA
                     ILIACDGFITLGLLTVWEYHYHDKNVVAGNPAKDCFSDH"
     gene            16327..16530
                     /locus_tag="ACOIAP_003085"
     CDS             16327..16530
                     /locus_tag="ACOIAP_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGZ2639962.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16612..17829
                     /locus_tag="ACOIAP_003086"
     CDS             16612..17829
                     /locus_tag="ACOIAP_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2639963.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         5889 a         3230 c         3746 g         5118 t
ORIGIN      
        1 taaaaactgg acttatcaca ctttatcaag gtcaaaacca ctcaatttac tactaattta
       61 ctacttatga atgagctttg atacgacgat ttatccttga aaagtgaaga tataaagata
      121 cttccaataa aatttgaata tttaataggt agacacttca aaaaatgagg tgtctatttt
      181 tttacccgat tttgaaagga agtgaactta tgaaaacaaa aaatcaagaa tcaaaaggtc
      241 gttccccact ctttaagacc atcaaacatt cattcagcca ataaaaaaga aaggataggt
      301 aaaaatatgg aacttaaatt tgtgattccc aacatggaaa aaacattcgg caatttagaa
      361 tttgctggcg aggataaagt cgttcagcga agaatcaacg gacggctaac tgtcttatca
      421 agaagctata atctctattc tgatgttcaa agagcagatg atattgtggt ggtgcttcct
      481 gctgaagctg gcgaaaaaca tttcggcttt gaggaacgtg tgaagttagt caatccacgt
      541 attaccgcag agggctacaa aatcggcact cgtggtttta caaattacct tttacatgct
      601 gacgacatga taaaagaata aagaaagaga ggaaaaatga tgagattagc aaatggcatt
      661 gtattagata aagacacgac ttttggagaa ttgaaattct ctgctctacg tcgtgaagtg
      721 agaatccaaa atgaagacgg gtcggtttca gatgaaatca aggaacgtac ctatgactta
      781 aaatccaaag gacaaggacg catgattcaa gtaagtattc ctgccagcgt gcctttgaaa
      841 gagtttgatt ataacgcacg ggtggaactt atcaatccca ttgcggacac cgttgctact
      901 gccacctatc aaggagcaga tgttgactgg tatatcaagg cagacgatat tgtgctgaca
      961 aaggattcta gttcattcaa agctcaacca caagcaaaga aagaaccgac acaagacaaa
     1021 tagtcgctag gtagaaagga gactttttcg catgaaacag cgtggtaaaa ggattcgccc
     1081 atctggtaaa gatttagtct ttcattttac gatagcgtca ctcctgcctg ttttcctgct
     1141 ggttgtcgga ctgtttcatg tgaagacaat ccagcagatc aactggcagg attttaacct
     1201 atcacaagca gataagattg acattcccta tttaattatc agtttcagtg tcgcaattct
     1261 tatctgcttg ctggtagcgt ttgtattcaa acgggttcgc tatgatacgg ttaaacaact
     1321 ttaccaccgt caaaaactgg caaagatgat acttgaaaac aagtggtatg aatctgaaca
     1381 ggtcaaaaca gagggtttct ttaaagatag tgctggtcgt acaaaggaaa agataaccta
     1441 cttccctaaa atgtattatc gacttaaaaa tggcttgata cagatacggg tggaaatcac
     1501 gctgggaaaa tatcaagacc aactcttaca cttggaaaag aaattagaga gtggcttgta
     1561 ctgtgagctg acggataaag agttaaagga ttcctatgtg gaatatactt tgctctatga
     1621 caccatagcc agtcgtattt ctattgatga agtagaagct aaagatggta aacttcgctt
     1681 aatgaaaaac gtatggtggg aatatgataa gctccctcat atgttgattg ctggtggtac
     1741 aggtggcggt aaaacttact ttatactgac actgattgaa gccttgcttc atacagattc
     1801 aaaactgtat attcttgacc cgaaaaatgc tgaccttgcg gacttaggtt ctgtgatggc
     1861 aaatgtctac tatagaaaag aagacttgct ttcttgcatt gaaacattct atgaagaaat
     1921 gatgaaacgt agtgaggaaa tgaagcagat gaagaactat aagactggca aaaattatgc
     1981 ttacttaggt ctcccggcac acttcttaat ctttgatgaa tacgtcgctt tcatggaaat
     2041 gctgggaaca aaagaaaaca ccgcagttat gaataagctg aaacagattg tcatgttagg
     2101 tcgtcaagct ggcttctttc taatactggc ttgtcaacgt ccagacgcaa aatatttagg
     2161 cgacggaatc cgtgatcagt ttaatttcag agtggcttta ggtcgtatgt ctgaaatggg
     2221 ctatggcatg atgtttggca gtgacgtaca aaaggatttc ttcttaaagc gaatcaaagg
     2281 tcgtggctat gttgatgtag gaacaagtgt catatcagag ttttatactc cccttgtacc
     2341 aaaaggatat gatttcttgg aggaaattaa aaagttatcc aacagcagac agtccacgca
     2401 ggcgacgtgc gaagcggaag tcgcaggtgt ggactgatct tgctggctgg tgtggcaata
     2461 gccacgccag cacttaaccc cccgtatcta acaggggggt acaaatcgac aggaaacagt
     2521 caaaaaaaca ttagaaaatc ctttggttac aagggattta caaaatttca gcgtatgtca
     2581 aatgggcttt aaaagttgac atacgccttt ttgattggag ggatttttac tgaatgaaca
     2641 aacttggtta cagcatttaa aagaaaaacg cttggcttat ggactatctc aaaaccgttt
     2701 agctgttgcg actggtatta caaggcagta tctaagcgat attgaaacag gaaaagtcaa
     2761 gccatcagag gatttacagc agtccctttg ggaagctctg gaacgcttca atcccgacgc
     2821 tccccttgaa atgctgtttg attatgtaag gattcgcttt ccgacaacag acgtacagca
     2881 ggtggtcgaa aacatcttac aactgaaact gtcctatttt cttcatgagg actatggttt
     2941 ctattcttat tcagagcatt atgctttagg cgacatattc gtcctttgct cccatgaact
     3001 ggacaaagga gttctggtgg aattgaaagg tcgtgggtgc agacaatttg aaagctatct
     3061 tctggcacaa caaagaagct ggtatgagtt ctttatggac gttttggtgg ctggcggtgt
     3121 gatgaaacgc cttgaccttg ccattaacga taagacaggg attttgaata tccctgtact
     3181 cactgaaaag tgccaacagg aagaatgtat ctccgtcttc cgcagtttta aaagctatcg
     3241 cagtggcgaa ctggtacgca aagaggaaaa ggaatgtatg ggaaacaccc tctatatcgg
     3301 ttcattacaa agtgaagttt atttctgtat ctatgaaaag gactacgagc agtacaagaa
     3361 aaatgatatt cccattgaag acgcagaagt aaaaaaccgt tttgagattc gattgaaaaa
     3421 tgagcgtgcc tattatgcag tccgtgattt actcgtctat gacaatccag agcataccgc
     3481 ctttaaaatt atcaatcggt atatccgttt tgtagataaa gacgattcca aacctcgttc
     3541 tgattggaaa ctgaatgaag aatgggcttg gtttattggg aacaatcgtg aacgattaaa
     3601 actaaccaca aaaccagagc cttactcctt ccaaaggacg ctgaactggc tatctcatca
     3661 agttgccccg accttaaagg ttgcgattaa acttgatgaa atcaaccaga cgcaggttgt
     3721 aaaagacatt ctcgaccatg cgaaactgac agaccgacac aagcagattt tgaagcaaca
     3781 gtcagtaaaa gaacaggacg tgataacaac aaaaaaataa ctcaaataca aattcattga
     3841 atatagagag gagaacattt ttatgaattt tggacaaaac ctttataact ggtttctatc
     3901 aaacgctcaa tcactggtgc ttttagcaat cgttgtgatt ggcttgtatc ttggcttcaa
     3961 gcgtgagttt agcaaactga ttggcttttt aattattgcg attattgcgg ttggcttagt
     4021 cttcaacgct gctggagtaa aagacatttt actagagcta ttcaatcgca ttattggtgc
     4081 ttaaataaaa ccgttctttt gtggaatata agtggttttc ttatgttccg caaaggaatg
     4141 gtacaccaaa cgaagtgcgg tagggatttt tgaatctcta caaagaaagg acgtgaatat
     4201 atggacgata tgcaagtcta tattgcgaat ttaggcaaat acaatgaggg cgaattggtc
     4261 ggtgcgtggt ttacctttcc cattgacttt gaggaagtca aagagaaaat cggcttgaat
     4321 gatgaatatg aggaatacgc cattcatgac tacgagttac cctttacggt tgacgaatac
     4381 acttccattg gcgaactcaa tcgactatgg gaaatggtat cggaattacc cgaagaatta
     4441 caatcggagc tatctgctct gctcactcat ttttcaagca ttgaagaact aagcgaacat
     4501 caagaggata ttatcattca ttccgattgt gatgatatgt atgacgtggc acgctactac
     4561 attgaagaaa cgggtgcttt aggcgaagta ccagctagtc ttcaaaacta tattgattat
     4621 caagcctatg gtcgggattt agacctttca ggaacgttta tctcaaccaa tcatgggatt
     4681 tttgaaatcg tctattaaat ctgtcggtac attactactg gcagattttc tattttacgg
     4741 ggtggctcaa tcagctaccc ctatttttta tgaaaggatt gattacatga agaaaatacg
     4801 aagctatacc agtatctggt ctgtggaaaa ggtactgtat tctatcaatg attttagact
     4861 tccgtttccc ataaccttta cgcaaatgac atggtttgtc gtgtcactct ttgcagtgat
     4921 gatacttggc aacttgcccc ctctttccat gatagaggga gcatttctca aatactttgg
     4981 gattcctgtg gctttcacat ggtttatgtc tacaaaaact tttgatggta aaaagcctta
     5041 tggatttttg aagtctgtca ttgcttatgc actgcgacca aagctgacct atgcaggaaa
     5101 aaaagtaacg cttggcagaa accagccaca agaagccatt acagcagtta ggagtgaatt
     5161 ttatggcata tccaattaaa tacattgaaa acaatctcgt ctggaataaa gacggggaat
     5221 gttatgctta ctatgagctt gttccttaca attactcatt tctaagtcca gaacagaaaa
     5281 tacaagtgca tgattctttc agacagctta tcgcacaaaa tcgtgatggc aaaattcatg
     5341 ctttacaaat cagtacagaa tccagcatac gttctgcaca agagcgttcc aaaaatgaag
     5401 tcactggcaa gctcaaagcg gttgcctatg acaaaatcga ccaacagaca gacgctttaa
     5461 tatccatgat tggcgaaaat caagtgaact accgtttctt tatcggcttt aagttgcttc
     5521 tcaacgatca ggagttttct atgaaaagtc ttaccgttga agcaaaaaat gctttgtctg
     5581 attttgtcta tgatgtgaac cataagctga tgggcgattt tgttagtatg agtaatgatg
     5641 aaatcctgcg ttttcagaag atggaaaagc tcttagaaaa taaaatctct cgtcgtttca
     5701 aaatccgcag gttagataag gacgacttcg gctatctgat tgaacacctt tacggacaga
     5761 caggcactgc ctatgaagag tatgagtacc atctatcaaa gaaaaagctg gataatgaaa
     5821 cgctgattaa atactatgac ttgattaagc ctactcgctg tttggtggaa gaaaaacagc
     5881 gatatttgaa aatccagcag gaagatgaaa ccgtctatgt agcttacttt accattaaca
     5941 gcattgtcgg agaactggac ttcccgtcct ctgaaatctt ctactaccag caacagcaat
     6001 ttacattccc gattgatacg tcaatgaatg tggaaattgt agcgaatcgt aaagccctat
     6061 ctactgtccg caataaaaag aaagaactga aagacttgga taaccacgct tggcaaagtg
     6121 ataatgaaac cagctccaat gtggcggaag ctctggaaag tgtgaatgag ctggaaacca
     6181 atttagacca aagcaaggaa tctatgtaca agctgtctta tgtggtaagg gtatcagcaa
     6241 atgatcttga cgaactcaaa cgtcgttgta atgaagtgaa agatttttat gacgatttaa
     6301 gcgtaaaact ggtacgacca tttggggata tgctcggctt acatgaagaa tttttacctg
     6361 ccagcaagcg ttatatgaat gattatattc aatacgtgac ctctgatttc ctcgctggtt
     6421 taggttttgg tgctactcaa atgctggggg aaaatgaggg gatttatgtt ggctacagct
     6481 tagatactgg acgcaatgtc tatctgaaac ctgctcttgc cagtcaaggg gttaagggtt
     6541 cagtaaccaa tgcgttagcg tcggcttttg ttggttcgct gggtggtggt aaatcctttg
     6601 cgaataacct tatcgtctat tatgcggtgc tttatggggc acaagcagtg attgtagacc
     6661 caaaagcaga acgtggcaga tggaaagaaa ccttgccaga gatttcccat gaaatcaata
     6721 tcgtcactct gacttctgat gagaaaaaca aaggcttact tgacccttat gtgattatga
     6781 aaaatcccaa agattctgaa tcactggcta ttgatattct gacattcctt acggggattt
     6841 cctctcgtga tggggaacgc ttcccaatcc ttagaaaagc cattcgtgca gtaaccaata
     6901 gtgaagtacg agggttgatg aaagtgattg aggaattacg ggttgagaat acgccactaa
     6961 gtaccagtat agccgaccat atcgaaagtt ttacagacta tgactttgca catttattat
     7021 tcagtaatgg ttatgtggag cagtctatca gcttagaaaa acaactgaac attatacagg
     7081 ttgcggactt ggtacttccc gacaaggaaa cttcctttga ggaatatacc actatggagc
     7141 ttttatccgt tgctatgctg attgtcatta gtacctttgc tttagacttt atccatacag
     7201 accgaagcat tttcaagatt gtagatttag acgaagcatg gagcttttta caggtagcac
     7261 aaggaaaaac actatctatg aagctggttc gggctggtcg tgctatgaac gctggggtat
     7321 atttcgtgac ccaaaataca gacgacctct tagatgaaaa actgaaaaat aacctcggct
     7381 taaaatttgc atttcgttcc actgacctta acgagattaa aaagacctta gccttttttg
     7441 gtgtagaccc agaggacgaa aacaatcaga agcgattgcg tgatttggaa aacgggcaat
     7501 gccttatcag tgatttatat ggtcgtgtcg gtgtgataca gttccaccct gtatttgaag
     7561 aactgctcca tgcctttgat accagaccac ctgtgcgaaa agaggtgtaa atgtgaaacc
     7621 atcaatagta aacagaataa aatcaaactg gacgctgaaa cgtctaggta aagtggcaat
     7681 gacagtggct ttcacacttg tgattgccat ttttctttta gccatgctgg gaacggtggt
     7741 tcaagctgcg ggcttggtag atgatacggt caatgtggca aatgaataca gccgataccc
     7801 acttgaaaac tatcaactgg atttttatgt ggataatagc tggggctggc ttccgtggaa
     7861 ctggtcggac gggattggaa aacaggtcat gtatggacta tatgccatta ccaattttat
     7921 ttggacaatc agtttgtatg tttccaatgc gacaggttac ttagtacagg aagcctattc
     7981 cttagacttc atttccgcta cagcagattc cattggtaag aatatgcaga ccttagctgg
     8041 tgtgagtgca aacggatttt caacagaggg tttctatgtt ggattcctct tactcttgat
     8101 tttggttctt ggggtttatg ttgcctatac gggactgata aagagagaaa ccacaaaggc
     8161 aattcatgcc attatgaatt ttgtgctggt gtttatccta tcggcttcct ttattgccta
     8221 cgctcccgac tacattaaaa aaatcaatga cttttcatca gacatcagta atgccagttt
     8281 atcacttggc acgaagattg tcatgcccca ttccgatagt caaggcaagg acagcgtgga
     8341 cttaatcaga gatagcctgt tttccataca ggttcagcaa ccgtggctac tgcttcaata
     8401 caacagttca gacattgaaa gtatcggtat tgaccgtgtg gaaagcctgc tctccaccag
     8461 cccagattcc aacaatggcg aagacagaga aaaaattgtt gcggaagaaa ttgaagacag
     8521 aagcaatacc aatctaacca ttacaaagac cattaaccgt ttaggtacag tcttcttcct
     8581 atttgtcttc aatattggga tttccatatt tgtattccta ttaacaggaa tcatgatttt
     8641 ctcgcaggta ctttttatca tctatgctat gtttctgcct gtgagcttta ttttaagcat
     8701 gattccatca tttgatggta tgtcaaaacg agccataaca aagctcttta ataccatttt
     8761 gacacgagct ggaatcacat tgattattac gacagcattt agtatttcaa ccatgctcta
     8821 taccttatcg gctggttatc cgttcttttt gattgctttt ctacagattg tgacctttgc
     8881 aggaatctac ttcaagctgg gcgatttaat gagtatgttt tctctacaga gtaacgattc
     8941 tcaaagtgtg ggaagtcgtg tgatgagaaa acctcgtatg cttatgcacg ctcacatgca
     9001 ccgtctacag cggaaacttg gacgttccat gactactcta ggggctgggt ctgccattgt
     9061 tacaggtaaa aaaggacagt cgggttcggg gagttctgca aggacacaag cagatcactc
     9121 ccgaccagac ggaaaggaaa aatcaacact tggaaaacgt atcggtcaaa ccatcggtac
     9181 agtagctgat accaaagaca gaatggtaga cactgctagt ggtttgaaag aacaggttaa
     9241 agatttgccg accaatgcaa gatatgcagt atatcaagga aaatccaaag taaaagagaa
     9301 tgtccgtgat ttaaccagta gtatttctca aaccaaagcg gacagagcca gtggacgcaa
     9361 ggaacagcag gaacaaaggc gaaaaaccat tgcgaagcgt cgctctgaaa tggaacaggt
     9421 caaacagaaa aaacagcctg cttcttctgt tcatgaaaga ccgactacaa gacaagaaca
     9481 atatcatgat gaacagacct caaaacagtc taatattcag acttcatata aggaatctca
     9541 acaagccaaa caagagcgtc cagcagttaa gtccgatttt tcaagtccaa aagtggaacg
     9601 ccaaggcaat accgttcaag aaaaaaccgt tcaaaagcca gcaacttcaa ccactacagc
     9661 agatagaact tcacaacgtc caatcacaaa agaacgtccg tctactgttc aaagagtacc
     9721 actacaaaat acaagaagta gaccaccaat caaaaccgcc accattaaga aagtcggtaa
     9781 gaaaccatga agttgaaaac tttagtgatt ggtggttctg gattattctt gatggtcttc
     9841 tcactgcttc tgtttgttgc cattttattt tcagatgaac aggacagcgg aatttccaat
     9901 attcattatg gaggtgtgaa tgtttccgca gaagtgctgg ctcataagcc tatggtagaa
     9961 aaatatgcca aagaatatgg cgttgaagaa tatgtcaaca tacttcttgc gattatacag
    10021 gtggaatcgg gcggtactgc ggaagatgtt atgcagtcct cggaatccct cggtcttcca
    10081 cctaattcat tgagtacaga agaatccatt aagcaaggtg tgaagtattt cagtgaatta
    10141 ttagccagta gcgaaaggct cagtgtagat ttagaatcgg ttatccagtc ctacaattat
    10201 ggtggtggtt tcttagggta tgtggctaat cgtggaaata aatatacctt tgaactggct
    10261 caaagtttct caaaagagta ttcaggtggc gaaaaagtgt cttaccccaa tcccatagcc
    10321 atacctatca atgggggctg gcgatacaac tatggcaata tgttttatgt gcaactggta
    10381 acgcagtatc ttgtcacaac agagtttgat gatgatacgg tacaagccat catggacgaa
    10441 gcactgaaat atgagggctg gcgatacgtt tacggtggag cttccccgac tacttctttt
    10501 gattgtagcg gactgacaca atggacgtat ggaaaagctg gaattaactt accacgaacc
    10561 gcacaacagc aatatgatgt gacccagcat atcccactat cggaagcaca agctggcgat
    10621 ttggttttct ttcattctac ctataacgct ggctcttata ttactcatgt tgggatatac
    10681 cttggcaata accgtatgtt tcatgcaggc gacccaatcg gttatgccga cttaacaagc
    10741 ccctactggc aacagcattt agtgggagca ggacgaatca aacaatgaga aaggaagatt
    10801 taatgatgaa atttagaaaa aatcagaata aagaaaaaca gataccaaag gaaaagaaac
    10861 ctcgtgtcta taaggtcaat cctcataaaa aggttgtgat tgccttgtgg gtacttttag
    10921 ggcttagttt cagctttgcg atattcaagc actttacagc tatagatact catactattc
    10981 acgaaacaac tatcatagaa aaggaatacg ttgatactca tcatgtagaa aattttgtag
    11041 agaactttgc gaaagtctac tattcatggg agcaatccga taagtccatt gataatcgaa
    11101 tggaaagtct aaaaggctat ctgacagatg aacttcaagc tctcaatgtt gatacagtac
    11161 gcaaagatat tcctgtatcg tcttctgtaa gaggatttca gatatggacg gtagagccaa
    11221 ctggcgacaa tgagtttaat gtaacctaca gtgtagacca gctcattaca gagggagaaa
    11281 atacaaagac cgtccactct gcttatatag tgagtgtcta tgtagatggt tctggaaata
    11341 tggtactggt taagaatccg accattacca acatacctaa gaaatcaagt tataaaccaa
    11401 aagccattga aagtgagggg acggttgatt ccattacaac caatgaaatc aatgagtttt
    11461 taacgacgtt cttcaagctc tatcctacag cgacagccag tgaactttcc tactatgtga
    11521 atgacgggat attaaaacca atcggaaaag agtacatctt tcaagaactg gtaaatccta
    11581 ttcacaatcg taaggataat caagtcacgg tatcgctgac agtggagtat atcgaccagc
    11641 agaccaaagc aacgcaggta tctcaatttg atttggtact tgaaaagaac gggagtaatt
    11701 ggaagattat agaataacaa atattggtac attattacag ctattttgta atcacgtact
    11761 ctctttgata aaaaattgga gattccttta caaatatgct cttacgtgct attatttaag
    11821 tatctattta aaaggagtta ataaatatgc ggcaaggtat tcttaaataa actgtcaatt
    11881 tgatagcggg aacaaataat tggatgtcct tttttaggag ggcttagttt tttgtaccca
    11941 gtttaagaat acctttatca tgtgattcta aagtatccgg agaatatctg tatgctttgt
    12001 atgcctatgg ttatgcataa aaatcccagt gataagagta tttatcactg ggatttttat
    12061 gcccttttgg gcttttgaat ggaggaaaat cacatgaaaa ttattaatat tggagtttta
    12121 gctcatgttg atgcaggaaa aactacctta acagaaagct tattatataa cagtggagcg
    12181 attacagaat taggaagcgt ggacaaaggt acaacgagga cggataatac gcttttagaa
    12241 cgtcagagag gaattacaat tcagacagga ataacctctt ttcagtggga aaatacgaag
    12301 gtgaacatca tagacacgcc aggacatatg gatttcttag cagaagtata tcgttcatta
    12361 tcagttttag atggggcaat tctactgatt tctgcaaaag atggcgtaca agcacaaact
    12421 cgtatattat ttcatgcact taggaaaatg gggattccca caatcttttt tatcaataag
    12481 attgaccaaa atggaattga tttatcaacg gtttatcagg atattaaaga gaaactttct
    12541 gccgaaattg taatcaaaca gaaggtagaa ctgtatccta atgtgtgtgt gacgaacttt
    12601 accgaatctg aacaatggga tacggtaata gagggaaacg atgacctttt agagaaatat
    12661 atgtccggta aatcattaga agcattggaa ctcgaacaag aggaaagcat aagatttcag
    12721 aattgttctc tgttccctct ttatcatgga agtgcaaaaa gtaatatagg gattgataac
    12781 cttatagaag ttattactaa taaattttat tcatcaacac atcgaggtcc gtctgaactt
    12841 tgcggaaatg ttttcaaaat tgaatataca aaaaaaagac aacgtcttgc atatatacgc
    12901 ctttatagtg gagtactaca tttacgagat tcggttagag tatcagaaaa agaaaaaata
    12961 aaagttacag aaatgtatac ttcaataaat ggtgaattat gtaagattga tagagcttat
    13021 tctggagaaa ttgttatttt gcaaaatgag tttttgaagt taaatagtgt tcttggagat
    13081 acaaaactat tgccacagag aaaaaagatt gaaaatccgc accctctact acaaacaact
    13141 gttgaaccga gtaaacctga acagagagaa atgttgcttg atgccctttt ggaaatctca
    13201 gatagtgatc cgcttctacg atattacgtg gattctacga cacatgaaat tatactttct
    13261 ttcttaggga aagtacaaat ggaagtgatt agtgcactgt tgcaagaaaa gtatcatgtg
    13321 gagatagaac taaaagagcc tacagtcatt tatatggaga gaccgttaaa aaatgcagaa
    13381 tataccattc acatcgaagt gccgccaaat cctttctggg cttccattgg tttatctgta
    13441 tcaccgcttc cgttgggaag tggaatgcag tatgagagct cggtttctct tggatactta
    13501 aatcaatcat ttcaaaatgc agttatggaa gggatacgct atggttgtga acaaggattg
    13561 tatggttgga atgtgacgga ctgtaaaatc tgttttaagt atggcttata ctatagccct
    13621 gttagtaccc cagcagattt tcggatgctt gctcctattg tattggaaca agtcttaaaa
    13681 aaagctggaa cagaattgtt agagccatat cttagtttta aaatttatgc gccacaggaa
    13741 tatctttcac gagcatacaa cgatgctcct aaatattgtg cgaacatcgt agacactcaa
    13801 ttgaaaaata atgaggtcat tcttagtgga gaaatccctg ctcggtgtat tcaagaatat
    13861 cgtagtgatt taactttctt tacaaatgga cgtagtgttt gtttaacaga gttaaaaggg
    13921 taccatgtta ctaccggtga acctgtttgc cagccccgtc gtccaaatag tcggatagat
    13981 aaagtacgat atatgttcaa taaaataact tagtgtattt tatgttgtta tataaatatg
    14041 gtttcttgtt aaataagatg aaatattttt taataaagat ttgaattaaa gtgtaaagga
    14101 ggagatagtt attataaact acaagtggat attgtgtcct gtatgtggaa ataaaacacg
    14161 attaaagata agggaagata ctgaattaaa aaaattcccc ctctattgtc cgaaatgcag
    14221 acaagaaaat ttaattgaaa taaagcagtt caaagtaact gtgattacag agccagacgc
    14281 aaagacgcag agccgataaa atgagattaa tacaatctca ttttatcggc tctttccgtt
    14341 atgtatggat tcttttaatt agtcttcgat gtttcttgct tcgttgatac cgctggctaa
    14401 agattccatt aaggatagtt ctttgtctgt aaagctatcc atgtatttct ctatctgtaa
    14461 tcgtcgggtg ctttttacca agttattagc aggtaagaaa aattcatcaa cggaaacatg
    14521 aagtaacgat acaaggtcat aaagaacttg tatgctgggg tgttgccctt tattttcaat
    14581 attagttaag taccgtgggt caatttcaat caatgctccc acttgttcac gagttaaacc
    14641 tcgtttcaat cgagcttctt taatggctaa accaaaggct ctaaaatcat atttatcttc
    14701 ttttttacgc atagtagacc acctctatac attttattgt tcctactgaa ttaaaaacag
    14761 gtatagaaaa acgtgttata tggtttatag gtttatattt aataaaaagc actactaaac
    14821 gccaataaaa aaaaccgtta tatggtagtg ctatttacgc tgttaaaata ttgtatatta
    14881 cttccaaatg gcggtttgtt ggaggtcaac gtcgccatga agtacatcat atacaataaa
    14941 tttccttaca ttgggttctt gtcaaaaaaa gtcgtctatc tgcaatagat aagtacgtcc
    15001 accaatgtgg ttttataaat catatagata gaataacaga agcatgtaaa cagagaaata
    15061 aatctgttta tatgcttttt tggctattca gaactttttt acaaagttta tttatcagta
    15121 atgcaacaaa tccccctttc acattgggac taagagtgaa aggagataaa cgagcaaggc
    15181 tcacttcctt tcctagacag aaagggggtg agaaacatga aaccatcttc ttttcagacc
    15241 acaatagaaa atcagtttga ctatatctgt aaacgtgcta tggaagacga gcgaaagaat
    15301 tatatgcttt atctttcaag gattgcaaag cgtgaggtgt ccttttcgga tgttggcgat
    15361 tatcttgtta gccagtttgc gacaacagat aactattcaa ctgactttca gatttttaca
    15421 ctcaatgggt tatcagtagg cgttgaaaat gatttgttga gtgaagcatt acgtgagttg
    15481 ccagacaaga aacgtgaaat tctactgctg ttttacttta tggacatgag cgattcagaa
    15541 attgcagacc tgttgaaatt gaaccgttct actgtctatc ggcatagaac cagtggacta
    15601 gccttaatta aaaagtttat ggaggaattt gaagaatgaa aacacaatat cctatgattc
    15661 cctttcctct cattgtaaag gcaacagatg gcgataccga agcgattaac cagattctac
    15721 atcattacag agggtacata acgaagcgtt ccctacgact tatgaaagat gaatatggca
    15781 atcaaagtat ggtcgttgat gaagtcttac gtggaagaat ggaaaccaga ctgattacaa
    15841 agattttgtc atttgaaatt aagtaatatc ctctctcctt tcgtggaagc gtgctaaacc
    15901 attccacgct tcccgaacag ggaggtttgt tattccacca aagcatattg agctttcaat
    15961 gtgttttgat aggctaacga gccattgttc tttgaaaact gaataaaagt aatcgaatac
    16021 gtttcgataa gaaaagagcc aacggaacta accgccatga cctatcttat aaagatagcg
    16081 agcgattcat gttagtgatc cgagaagcaa tctttagcag gattgcctgc aacgacattc
    16141 ttatcgtgat aatgatactc ccatacagtc aatagtccga gcgtgataaa accgtcgcag
    16201 gcaatgagta tggctacatg agaaccatgc aggggtggaa ctcccgtgag ctttgctaaa
    16261 gctgttcgat tgctggtaaa acaactttta tgaaatccaa ataagtgatt tggaaaggag
    16321 gattttatga agcagactga cattcctatt tgggaacgtt ataccctaac cattgaagaa
    16381 gcgtcaaaat attttcgtat tggcgaaaac aagctacgac gcttggcaga ggaaaataaa
    16441 aatgcaaatt ggctgattat gaatggcaat cgtattcaga ttaaacgaaa acaatttgaa
    16501 aaaattatag atacattgga cgcaatctag cgtcgccaaa gggtcttgta tatgataaaa
    16561 tagtattaag tcgtatcaag gctctttcca taaaggaaag gagcaaatgc catgtcagaa
    16621 aaaagacgtg acaataaagg tcgaatctta aagactggag agagccaacg aaaagacgga
    16681 agatacttat acaaatatat agattcattt ggagaaccgc aatttgttta ctcgtggaaa
    16741 cttgtggcta cagaccgagt accagcagga aagcgtgatt gtatctcact tagagagaaa
    16801 atcgcagagt tacagaaaga cattcatgat ggtattgatg ttgtaggaaa gaaaatgaca
    16861 ctctgccagc tttacgcaaa acagaacgct caaagaccaa aggttagaaa aaacactgaa
    16921 actggacgca aatatcttat ggatattttg aagaaagaca agttaggtgt aagaagtatt
    16981 gacagtatta agccatcaga cgctaaagaa tgggctatta gaatgagtga aaatggttat
    17041 gcttatcaaa ccatcaataa ctacaaacgt tctttaaagg cttcattcta tattgctata
    17101 caagatgatt gtgttcggaa gaatccattt gactttcaac tgaaagcagt tcttgatgat
    17161 gatactgtcc ctaagaccgt actaacagaa gaacaggaag aaaaactgtt agcctttgca
    17221 aaagctgata aaacctacag caaaaattat gatgaaattc tgatactctt aaaaacaggt
    17281 cttcgtattt cagagtttgg tggtttgaca cttccagatt tagattttga gaatcgtctt
    17341 gtcaatatag accatcagct attgagagat actgaaattg ggtactacat tgaaacacca
    17401 aagaccaaaa gtggcgaacg tcaagttcct atggttgaag aagcctatca agcatttaag
    17461 cgagtgttag cgaatcgaaa gaatgataag cgtgttgaga ttgatggata tagtgatttc
    17521 ctctttctta atagaaagaa ctatccaaaa gtggcaagtg attacaacgg catgatgaaa
    17581 ggtcttgtta agaaatacaa taagtataac gaggataaat tgccacacat cactccacat
    17641 agtttgcgac atacattctg taccaactat gcaaatgcag gaatgaatcc aaaggcatta
    17701 cagtacatta tgggacatgc taatatagcc atgacgctga actattacgc acatgcaaca
    17761 ttcgattctg caatggcaga aatgaaacgc ttgaataaag agaagcaaca ggagcgtctt
    17821 gttgcttagt agtacaaatg aatttactac ttatttacca cttctgacag ctaagacatg
    17881 aggaaatatg caaagaaacg tgaagtatct tcctacagta aaaatactcg aaagcacata
    17941 gaataaggct ttacgagcat ttaagaaaat ataaaaagat aat
//
LOCUS       DBGJFK010000082        17829 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.082, whole genome shotgun sequence.
ACCESSION   DBGJFK010000082 DBGJFK010000000
VERSION     DBGJFK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.082"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            201..692
                     /locus_tag="ACOIAP_003087"
     CDS             201..692
                     /locus_tag="ACOIAP_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HGZ2639964.1"
                     /translation="MYENNKVIYNFERCEKLEKTLYLSQFNTYKNFKLTSKKTVINSF
                     ETYVCNMNIRSISLVDTIECISLEDEQLTGKKLILVGDIDTDVILDYVANKRNRNSSK
                     KNILKLKIPFSTFIQIPRKIENKDKINLKYLIQDISSSILDDNNLFISVTAIISYENS
                     SQI"
     gene            723..1670
                     /locus_tag="ACOIAP_003088"
     CDS             723..1670
                     /locus_tag="ACOIAP_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639965.1"
                     /translation="MRITKTTFNDVFSNDTNGSILKVEKYVDKKCASVFDILTYTIIV
                     TNVSRYKTGNIFFKDYISKYIEFVNNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNIDKFPTRISIESNRVYTNINKIVFKQLNISN
                     TLKAPKNLKDILKVNANSKILDVKPIKNPTNKGNNLKSCNLIVFGSVDVEVDYSCKNR
                     SKFKTVNKSSDIQKDKHYSNDIQNNNKTISDCKRQISIGNNKVKKITKTFGFSCFICS
                     PVGIVYEDMKNINIKIEHTSINELNPDELFINTSLLLYY"
     gene            1960..2502
                     /locus_tag="ACOIAP_003089"
     CDS             1960..2502
                     /locus_tag="ACOIAP_003089"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2639966.1"
                     /translation="MKICITVGHSILKGGKSTGASGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDIIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGN
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            2830..4323
                     /locus_tag="ACOIAP_003090"
     CDS             2830..4323
                     /locus_tag="ACOIAP_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGZ2639967.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLEYNIPSRVQIEVIPKLLNGQNLV
                     VKSKTGSGKTASFAIPLCENINVEYNNIQALIVVPTRELALQVKDEISSIGRLRKVRC
                     SAIFGKQPIKEQIAELKQRVHIVVATPGRIIDHINKGTIKLEDIKYLIIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVGLFSATIDEEIKYICEKYIPDYSVINIEENKSDTNQRTR
                     QIDDKIIKTNEREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKKQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKRNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKE
                     ILKEVSKRKKADKNSYKGKDIKLNTESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKHKEIPIKKKMVKVKRDIR"
     gene            4562..5326
                     /locus_tag="ACOIAP_003091"
     CDS             4562..5326
                     /locus_tag="ACOIAP_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGZ2639968.1"
                     /translation="MAYFNYNNKQCYYNEIGDGTPLLFLHGNTASSKMFNEIINFYKD
                     EYKVILIDFVGHGKSQMVDKFAADLWFDEAMQVICFLEVMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWER
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDDFVSLISNDFFENTFSSLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(5611..8790)
                     /locus_tag="ACOIAP_003092"
     CDS             complement(5611..8790)
                     /locus_tag="ACOIAP_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HGZ2639969.1"
                     /translation="MKIDMIYKLIRRNTEPSRWARGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSNGKNIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSSTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINMDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYDPNIHYFADED
                     EKLVDIIEEYGTNLSYSFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPIRFDLKNIEDKIVLCSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQVLSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DSNICCDVKYIYDDEDKKFVLPNIQKETTIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSDKFKLKKIYNASSIKASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMGTSKNNKIHKNKALYIN
                     DMIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGSKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPLALV
                     TASVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKIKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSIDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIIDLFN"
     gene            9071..11248
                     /locus_tag="ACOIAP_003093"
     CDS             9071..11248
                     /locus_tag="ACOIAP_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HGZ2639970.1"
                     /translation="MYNKCNNLYLLLGKENINMDSYRQLKAKIPCKETGIEIRRTLCD
                     ICSPGVHCGIDAYVKNGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKTISWDEAYREIAEKLNKVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLT
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQRDLIDKEYIE
                     KHIHGFNEYKEYVKLFDLDTVSRITRVSKDNIVKAVEMLSQGSFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALDSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANVMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTYLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKTNR"
     gene            11262..11684
                     /locus_tag="ACOIAP_003094"
     CDS             11262..11684
                     /locus_tag="ACOIAP_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2639971.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GESIEYFSLACIHCDEPKCLDVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGMDGKANKCNGCVERYKCGMDSPCVMVCPTGALKFNK"
     gene            12092..12895
                     /locus_tag="ACOIAP_003095"
     CDS             12092..12895
                     /locus_tag="ACOIAP_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGZ2639972.1"
                     /translation="MKKIKLIIMLALVSAFLITGCSSENNKNKEEQKTIRVATSGTYY
                     PFAFKEKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYDFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKLVEPPIQFGAC
                     SFALQKNEKGERWTKEINKVIEDMHKDGTLTKISKAWLGKDITKEPINE"
     gene            12888..13556
                     /locus_tag="ACOIAP_003096"
     CDS             12888..13556
                     /locus_tag="ACOIAP_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGZ2639973.1"
                     /translation="MSSFNFEFCLNIFPFLIKALGITILISIIAFFISILLGVILAFF
                     TQTKSKILQYITRVYVSFFRGTPLLIQIFFFYFGFPMVFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMVTILIYWAVSIMLSNIQSKVEKRI
                     GKAY"
     gene            13791..14453
                     /locus_tag="ACOIAP_003097"
     CDS             13791..14453
                     /locus_tag="ACOIAP_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGZ2639974.1"
                     /translation="MIFNMKYFLELFPIIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDKGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            14513..15310
                     /locus_tag="ACOIAP_003098"
     CDS             14513..15310
                     /locus_tag="ACOIAP_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2639975.1"
                     /translation="MIKRNIIKCLVAVLSLTVLVTGCSKKEEVKDEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVAASVNKD
                     NLFEEKVYGDGTNGLQDLDLGRVSAWIDAELTVIGDAKKANMKVRVLDEKLSVTNIAY
                     FFKKNDEKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            15443..16618
                     /locus_tag="ACOIAP_003099"
     CDS             15443..16618
                     /locus_tag="ACOIAP_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGZ2639976.1"
                     /translation="MIETKIKSIALKNREKIIKIRRQIHSNPELAFKEFKTSKLIKEE
                     LNKLNIEYIDVAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSINDNMHA
                     CGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGVDALAT
                     GHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAVYSSIQ
                     QIVSRKINPVIPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISQEKVIEISKILENIV
                     RGVCKSNGADCKFEKSMGGDAVINDKDMIELGKKSACKILGYENVEMIDFPAMTGEDF
                     AIYMKERPGLFMYIGVGSEEKNINYRLHNNKFDIDEKCLSVASSLFSQLAVDYLCQL"
     gene            16727..17476
                     /locus_tag="ACOIAP_003100"
     CDS             16727..17476
                     /locus_tag="ACOIAP_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639977.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEINQSEVVAILGPSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVERTTKKDIANLRKHTSMVFQNYNLFKNKTALENIM
                     EALIVVHKKGKQEAREISLKLLDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDKGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIKKEEVFS"
BASE COUNT         7057 a         1814 c         2865 g         6093 t
ORIGIN      
        1 ttccttataa aaaagtcaat agatatatac aataaaaaat tctcaaaaag acttttactt
       61 gcaaattgaa attaatgaag taaaaaagta ttctttatta aaagtagatg gcaactatat
      121 agtgaataat aaaaaatggt aatttgaaat aatttttatg aatagtatta atatatagat
      181 acagggagat tgatgcgatt atgtatgaaa ataataaggt aatatacaac tttgaaagat
      241 gtgaaaaact agaaaagact ctttatttat ctcaatttaa tacatataaa aattttaaat
      301 taacttctaa aaaaactgta ataaattcat ttgagacata tgtttgcaat atgaatattc
      361 gcagtataag tcttgttgat actatagaat gtatatcatt agaagatgaa caactgacag
      421 gaaaaaagtt aattttagtt ggtgatatag atactgatgt aatattagat tatgtagcca
      481 ataaaagaaa tagaaattct agtaaaaaaa atatacttaa attaaaaata ccctttagta
      541 catttataca aatacctaga aagatagaaa ataaagataa aattaattta aagtatctta
      601 tacaagatat ttcctcatct attttagatg ataataattt atttattagt gttactgcaa
      661 ttataagtta tgaaaatagc tctcaaatat agtaatattt aaattataga aaggtggatg
      721 caatgagaat aacgaaaact acttttaatg atgtattttc aaatgataca aatggaagta
      781 ttttaaaagt agaaaaatat gttgataaaa aatgtgcatc tgtatttgat attttgactt
      841 atactattat tgttacaaat gtaagtagat ataaaactgg aaatatattt ttcaaagatt
      901 atatttctaa atatatagag tttgtaaata atactgtaaa agttaatggt attataaagc
      961 gtggattaga cccacaacaa ggtttttata tagggagaat agatgcaagt tgtaaaaaaa
     1021 taatatcttt taaaagtgta gttttaccaa attcggcaca taggattata aagaatagtg
     1081 ccaatatata ctattactac aagtgtaata tagataaatt cccaacaaga atatcaatag
     1141 aaagtaatag agtttacact aatataaata aaattgtatt taaacagttg aatataagta
     1201 atactttaaa agctcctaaa aatctaaagg atatattaaa agtaaatgca aatagtaaaa
     1261 tacttgatgt taaacctata aaaaatccta caaacaaagg taataatttg aaatcatgta
     1321 accttatagt ttttgggagt gtagatgttg aagtagacta tagttgtaaa aatagaagta
     1381 agtttaaaac agtaaataaa tctagtgata ttcagaaaga taagcattat agcaatgata
     1441 tacaaaataa taataaaact ataagcgatt gtaaaaggca aataagtatt ggtaataata
     1501 aagtaaaaaa aataacaaaa acttttggat tttcctgttt tatttgttca ccagttggaa
     1561 ttgtttatga agatatgaaa aatataaata taaaaattga gcatacatca ataaatgaat
     1621 taaatccaga tgaattattt ataaacacat cgcttttatt atattattag gtattttaaa
     1681 tctaaaactt aaaattatta aacgagcatt tgattaaaga gaagtatata ttgatatatt
     1741 tattttatgt gtaaatgatt aattaaataa ttataagtaa taagtatagt ataatattta
     1801 aaaaatatgt atttatgata aaataagaca aatatgttaa aaaaatgata atcacggaga
     1861 acttttacct tctccaatta atatattatt attagtaata actttaagat tatattacta
     1921 ttatataaaa attggcttaa aagaaggtga aaaaagtaaa tgaaaatatg cataacagta
     1981 ggtcatagta tactaaaagg tggtaaaagt acaggtgcaa gtggtatagt tgatgaatac
     2041 aattataaca aaaaattagc tcctatgtta gctgagatgc ttataagtca aggtaataca
     2101 gtagatataa taatttgtcc agaaagacac tttatgtcag aaagagaaga atttttctat
     2161 agagttccaa aagtaaacag tggtaaatac gatttattag tagagctaca tttaaataaa
     2221 gctgatggaa cacaatgtgg tacagaagtg ctttactatg gtaatgaagg attagaatat
     2281 gctaaaagag tatctaatag acttggagaa ttatttgaaa atagaggagc taaaaaaaga
     2341 gaaaatttat atatattgag aaatacaaat ccagttgcaa tacagattga aagttttttc
     2401 tgtgataatg tgaatgattg taacaaagca aatgaatcag gttatgatta tatagcacga
     2461 ttgattacag aaggtatatt gaataaagat ataaatatgt gagattatgg tgatttaggt
     2521 attgattaat acctttaata ttagatataa ataaaataca atatattagt ataatttaaa
     2581 cttgtaaaag atatattagt agtttagttg ttgacaaggg atacctcctt gaaaatattg
     2641 atttatcagt attttcaagg aggtatttaa atataaaaat ttaatttatt tactactaaa
     2701 ttatagcttt acatagtata tattttatct tcactctaat aaataatata aaaatagtag
     2761 aaccttgtat tataataata taatgtagaa aaatacatag ataagataaa tataataagg
     2821 tggtaatata tgaaatatac atttgaaaaa tttaagttaa atgaaaagat acttaagtca
     2881 ttgaagagtt tagaatataa tataccttct agagtacaaa tagaagttat tccaaaatta
     2941 ttaaatggtc aaaacttagt agtgaagtca aaaacaggaa gtggaaagac agcaagtttt
     3001 gcaatacctt tatgcgagaa tataaatgta gagtacaata atattcaagc acttatagta
     3061 gttccaacaa gagaattggc tttgcaagta aaagatgaga tatcgagtat aggaagacta
     3121 aggaaagtga gatgtagtgc tatatttggc aaacaaccta taaaagaaca aatagctgaa
     3181 ttaaagcaaa gggttcatat tgttgtagct actccaggta gaataattga ccatataaat
     3241 aaaggtacta ttaagttgga ggatataaag tatttaataa tagatgaggc cgataaaatg
     3301 tttaataaag gttttgttga acaaatggaa aaaatattat taaatttacc taaagagaaa
     3361 atagtaggtc ttttttcagc tacaatagat gaagagataa aatatatatg tgaaaaatat
     3421 ataccagatt acagtgttat aaatatagag gaaaataaga gtgatactaa tcaaagaaca
     3481 agacaaatag atgacaaaat aatcaagacg aatgaaagag agaagtatat ccttttaaaa
     3541 gaattaatat acagcgaaaa tccaaagagt gtgataatat tttgtaatac taaagagaaa
     3601 gtatctaaat tatataataa gatgagtaaa gaaggttttt taataagaga gttacatgca
     3661 gatttatcgc aagaaagaag aatttttgtg attaaggatt ttaaaaaaca aaagtttaat
     3721 gtattagtta gtagtgatgt agcgtctaga ggaatacata ttgatgatat ttctttagta
     3781 ataaattatg atgtgccaca agataaagaa aactatatac atagaatagg tagaactggt
     3841 aggaagagaa atagtggaaa ggcaattact atagtaactg aaaaggatga aaaatatata
     3901 gagaatatag aaacgtatat aggatacaaa ataaatgaat taaaagatat agaaaaaagc
     3961 agaattacgc atggcaaaat tttatttgaa gaatattcaa aagaaatcct aaaagaagtg
     4021 tcaaagagaa agaaagccga taaaaattct tacaaaggta aagatataaa actaaataca
     4081 gaaagtgaag ttgttaaatt atatttaaat gctggtaaga agaagaaaat aagagtctta
     4141 gatatcgttg gtgcatttag taatataaaa ggtattacta atgatgatat aggtgtaatt
     4201 gaagttcaag atttatgttc atatgtagat atattaaatt ataagggaga tttaatatta
     4261 aaaaaacata aggagatacc tataaagaaa aaaatggtta aggtgaaaag agatatacga
     4321 taatttagtt attactgctc tttctgatga agaaatcgta ggtttaagta aaagtatcaa
     4381 tgttgatgaa ttgctctgtt atctaaatga agttgcaaaa aaacaataga agttgttaag
     4441 taaaagaatg ttgattttac ctatattcta ggctatacta tttttaagtg attatgctaa
     4501 tagtcatttt aaatataagt aataaatata tgtttataga aacataaaag gagggaaata
     4561 tatggcatat tttaactata ataacaaaca atgctactat aatgaaattg gagatggtac
     4621 accattactt tttttacatg gaaatacagc ctcttctaag atgtttaatg agataatcaa
     4681 tttttataaa gatgaatata aagtaatatt aattgatttt gtaggtcatg gaaaatctca
     4741 aatggtcgat aagtttgccg ctgacttatg gtttgatgag gctatgcaag tgatatgttt
     4801 tttagaagtg atgaactata aaaaagtaaa cataattggt agtagtggag gagctcttgt
     4861 tgcattaaat gttgcacttg aaagacctga tttagtgaat aaggtaattg cggatagttt
     4921 tgaaggagaa gttcctctag agtcatttgt acaaaatgtg aaaatagagc gtgaagcatc
     4981 aaagcaagat gatggtgcaa aagcttttta tatttataat caaggagaaa attgggaaag
     5041 agttgtagat aatgatacag aagctatttt tgaacattat aaaactatag gaaaattttt
     5101 tcataaacct ctagaaacta tgcaaccaga ggtgctttta acaggaagta gagaagatga
     5161 ttttgtatct ttaatatcta atgatttttt tgaaaatact ttttcatcac ttcttgaaaa
     5221 gattaaaaat ggtaaaatgt atttgtttga taaaggtggt catcctgcaa ttttatcgaa
     5281 tggattagat ttttcaaatg tagcaaagaa atttttagaa gaatgattta acccaaattt
     5341 ataataatga aaactataaa atagattgta aaacttacaa aagtaagtgt acatatactt
     5401 tattcttatg atgaaataga attgttaaaa caaaatattc taatagttaa gttattacat
     5461 ttgtatattc aataggtgta gaaagagata ttattggatt ataaagttgg gattaaataa
     5521 taatatgaag ttttatttat tcaagtattg tagcttaact atataaatct tagaataaat
     5581 ttatatagtt aagttgtagg attaaataat ttagttaaat aagtctatta tctcctcatc
     5641 agatagactt tttaatacac cttcattaga aagttctcca tttataaatt gatttataag
     5701 ttctttttta ctttcttgta attttattat cttttcttct atagttcctt tagcaatcaa
     5761 ttttataact tgtactgaat ttttttgacc aaatctatga gctctatcac tagcttgatt
     5821 ttctactgat ggattccacc atgggtcaaa gtgaattacc atgtcagcag atgtaagatt
     5881 taaacccgtt ccacctgctt ttaaagatat taaaaaaact tttttatcta tactgttatt
     5941 gaactcatct acaagttcaa gtctttcttt agcattagtt ttaccatcta tataatggta
     6001 tttaatttta tacttatcaa gttccttact tatgttctta agcacagagg taaattgtga
     6061 gaacaacaat attttgtggt tttcgtttat actatctcta agtatttcta aacatgtttc
     6121 aatttttgaa cttttcttat tgtaatcttt tactactata cttgggtcta aacaaagttg
     6181 tcttagttta gttaaataag aaaatataac tattttatct ttctttagat ttttatcttt
     6241 tattttatct tgtatatcct ttgaatatac actatatatc tttttctgct ctttattcaa
     6301 ttcaacaaaa aagtttttct caatcttatc tggaagttct ttcataactt gttttttact
     6361 tcttctaaga ataaaaggtt ttatcaattt tttcagattt ttaacattat cttctttatt
     6421 tataaataat tcctgaaact ttgctttact atatagatag ccaggcatta taaaatcaaa
     6481 tatagaccat aattctagga gattattttc cataggtgta ccagtgagtg caaatttatt
     6541 ttctgcattt atacttttta cagaagcagt tactaaagct aatggatttt ttatattttg
     6601 agcttcatct aatatgcaat aatcaaattt tatttcacta tatttttcta aatcatttct
     6661 aagagtacca tatgttgtaa gtattacatc aaaattttct aattccataa aacatttttc
     6721 tctatctctt ttacttccat gtatcaataa aacttttata tctggagcaa atttttcaaa
     6781 ttcattcttc caattataaa tgagtgatgt tggtgtaaca ataagacttt ttttattgga
     6841 taatgataat aaaaatgcaa tagtctgtat tgttttacca agacccattt catcagctaa
     6901 tataccacca aatttataat aatctaaaac tttaaaccag ttgagaccat ttatttgata
     6961 gtcacgaaga tttgcattta aatttgcggg aatttctaaa tttatactat caaagtttct
     7021 aaatttttca catatactgt ctagttcttt tttaccatct ataaacttca aatttttact
     7081 acgtatcata tcatttatat atagagcttt atttttatga attttattat tttttgatgt
     7141 acccattata tctagatttt caactaattc aaaaaaatct tttgtttctc tttctgataa
     7201 atctataaag tttccatctt taagtttata aaaagtgcgt ttttcttgaa aagcttttaa
     7261 aatgtctttg tactcttttg gatttatatc agatatatta aaattaaatt ctagataatt
     7321 ctggttagtc tgattgattg aagctttaat tgatgaagcg ttatatattt ttttcaattt
     7381 aaacttatca gaataatata tatctccaaa ttcctttaga gattctaatt gtaaatctaa
     7441 aaatgtaaat aggtcgtggt cagttccttt aaacacataa tgattatttt cttttgtaaa
     7501 ttgtgaagaa gtcagtttat tttcaatggt agtttctttt tgtatgttgg gaagtacaaa
     7561 ttttttatct tcatcatcat atatatactt tacatcacaa catatattgc tatcaatcat
     7621 atcaaaatag aactcagatt taaaatcttt tgttatatta ttttttatgt tatcatctaa
     7681 atgaacttct tgagatatag attttaatct aggaactagt aatcctaaaa catccttaga
     7741 atcctcttta tcaaatttta gctctttagt ctttgataat acttgatata tttttgaata
     7801 atcatgagct tttttatggg ataacaaata gatattgcca tcatataaaa gtacatcatt
     7861 ttttttagta agtggaacag gtagtgaatc tttagaacat aagactattt tatcttctat
     7921 attttttaag tcaaacctta taggtagagt atcatttaat atttttgggt gatattcttc
     7981 tttagaaaaa ataagggtaa aatctttgta cttaatagca tttaaaaatt gttttaaaga
     8041 gcttgcattt atctccataa atttttttga gtgtgatgaa gaaaaactgt atgaaagatt
     8101 tgtcccatat tcttctataa tatctactaa cttttcatct tcatcagcaa aataatgaat
     8161 gttgggatca taagtaaatt ttttcccaaa atctaattca tatccattaa gttttgaata
     8221 tgcaaattca gtaatgtttt ttaaaatgta cattttatca attcctattt taaattcagc
     8281 aattgcttta tttgaatcca tatttatcaa tacatctaaa ttaacccttt ctcttttagt
     8341 attatctaac aaagaaagta attgcttgct taaatctaag ctggttttag aatttgtact
     8401 agagagctta tccttatctg cacctaatat atctattaga ataggaggaa catctttttt
     8461 attttttatt tgttttaagc tttttatcac aatagcaact atatgtttac atataaaaat
     8521 gtttttacca tttgattgac agtcagcaca actgcaatca ttttcaatta tcttaaagtg
     8581 ctttatatct atagttattg agttaaaata aaagctataa ttatcttcag aattgactcc
     8641 accacgaaat gtcagcagat tattttgtag gtcatcaata tctatgtcta tataatcaac
     8701 tagttgattg gtgtaatatt ttacacctct tgcccatctt gatggttctg tatttcttct
     8761 tattaattta tatatcatat ctattttcat attattcacc ttacctcact gtatatatta
     8821 taatctaaat gcattcaatt tacactctaa atttaagact aaaattaggg cagatattga
     8881 tagcttttat ctattgcaag atatgtataa ataacaattt actattagat ttttgttgaa
     8941 ttatcttata aactatgagt gaaaaataat tatataaata cattattagt aaatataaaa
     9001 ttttattatt aaaactattc tttgaaatta caatatataa aatataaatt atgatatttg
     9061 aataaaaaga atgtataata agtgtaataa tttatattta ttattaggaa aggaaaatat
     9121 taatatggat agttatagac aacttaaagc taaaatacca tgtaaggaaa caggtataga
     9181 aataaggaga actttatgtg atatttgttc cccaggagta cattgtggaa ttgatgcata
     9241 cgttaaaaat ggtaaagtaa taaaaataga aggtacaaaa gaacatccaa tgaataaagg
     9301 attgttatgt acaaaaggtc tttgcaatag agaatatatc tatagagaag atagaataaa
     9361 aacacctcta aaaagaattg gaaaaagagg tgaaggaaaa tttaagacaa tatcatggga
     9421 tgaagcttat agagaaatag cagaaaaatt aaataaagta aaatctgagt atggagcaaa
     9481 gcatgtagct ttttttacag gttatggaaa gtggtataga ccgtttttac aaaggtttgc
     9541 atcttcattt ggttctccta attatggtac agaatctagt tcatgttcaa catcagcaca
     9601 gatggcggga aatgttgcta ctggaagaaa ctttacaatg caagatatgg agaatgcaaa
     9661 aacttactta ggatggggat ttaatccata ctactctaaa tttttaaata gtgtaaatct
     9721 aacaaaatta aaagaaaaag gtctaaaatt tataattgta gaccctagga taacaccaac
     9781 aacccaaaaa ctagcggatt tacatttaag aattaaacct ggaactgatg gggctttagc
     9841 tcttggaatg gcgaatctat ttatacaaag agatttaata gataaagaat acatagaaaa
     9901 gcatatacat ggatttaatg aatataaaga atatgtaaaa ctatttgatt tagatactgt
     9961 aagtagaatt acaagagttt ctaaagacaa tatagtaaaa gctgtagaaa tgttgtcaca
    10021 aggttcattt tgtataaatg aaagtgcagc tccaatagtt catcatcaaa atggattcca
    10081 aaactataga gcaatgatgt ctttatctgc tataacaggc aattatgata gaataggtgg
    10141 aaacatacca aaacaagatt actttgctgg taagataggt ggattccaaa cactagaaaa
    10201 agagtttgta aaagaagttc tacctaaaaa tataaatgaa agaattggtg gagaaagatt
    10261 ccctctatgg aatgaaatgg taactcaatt tcaagctatg gatttaccta ggcaaataga
    10321 agaaaagaca ccatatgaaa taagagcttt gttttgtcat gggataaatg ctagaatgtt
    10381 tcctaattca gggagacttt ttaaagcatt ggatagtgta gatttttttg tgaatataga
    10441 tttatttatg acagatacat caaaatatgc agatatactt ttacctgcat gtacatcatt
    10501 cgagagagaa gaatgtaaga gctatccagg agggtatatt acatatacca aaaaagttat
    10561 tgataaatta tacgattcaa aatcagatgt agaaatactt tcagatttag caaatgttat
    10621 gaatatagat gatgatttat taaaagcagg ttatgaagca agtataagac atatgtttaa
    10681 aaatacgtgt gtagatgtag ataaacttaa agaaagtgat ttaccattaa aatgtaaaga
    10741 ttttaagcca tatatagtag gttcatatac aagagaaggg tatgatacta gtacttctag
    10801 gtttgaatta aaatctacaa ttattgaaaa atataaagat tttgggctgg atgcactacc
    10861 aacatataga ggatttaatg ataatataga tgatgaatat acttatttat tgacatcagg
    10921 agcaagaatt tcaaatgcac tacattcaag acttcatgac atcaaacttt caagaatatt
    10981 aaaaaatgaa gctagttgtg atatttctag cttagatgca aaagaattgg gtgttatcag
    11041 tggagattat ataaaaataa ctactaagat aggaagtttg gatgtaaaag tcaatgttac
    11101 tgatagagtc ttatataaga atatacatat gtatcatgga tatagagaag ctgatataaa
    11161 tagtattatt tgtgataatt ttgaccctta tagtggattc cctgcgtata gaagttgcaa
    11221 gtgtaagatt gaaaaaacaa atagataaat ggagagatat aatgaaaagt ttatttaaat
    11281 ttaataaaga attatgtaca gcatgtggag catgtttgct tgcatgtata gaccaaaatg
    11341 ataataatat agataatggt gaacttttta gacatgtatt tacaatagag gaaggtgaaa
    11401 gtatagaata tttttcatta gcatgtatac attgtgatga gccaaaatgt ttagatgtat
    11461 gtcctaaaaa ttgttttaaa aaagaagaag gattcgttgt attagataat caaaactgta
    11521 tagggtgtaa actttgtgaa aaagcttgtg aatatggagc cctaatttat ggaatggatg
    11581 gtaaggcaaa taagtgtaat ggttgtgtcg agagatataa gtgtggtatg gattcacctt
    11641 gtgtaatggt atgtcctaca ggagcattga aatttaataa atagattaaa tatatagagt
    11701 gacttatact tagatataag atatttttac aaaaagctat attgagtttg ttataataaa
    11761 aactcaatat agctttttgt atggatatag ttggatacta taatatgatt cttagtaata
    11821 gttttttgct attggacaaa gactgtaaaa catattaaac ttatgttgtt caaagtcgaa
    11881 gtataatata ataactagaa aattgattta tagtgttata aaagcaaatt taggaaggta
    11941 taaaatctga agtaattctt tactacagta tcaatacttg gagttctgtt atggcagagt
    12001 cattaaacaa ttataatggt acaagtgatt caattgctgg aaatgtatta tataaaaatt
    12061 taaaaaaaga ttaaaaagga gagaataaat tatgaaaaaa attaaattaa ttattatgct
    12121 tgccttggta tcagcatttt taattacagg atgctcatca gaaaataata aaaataaaga
    12181 agaacaaaaa actataagag ttgcaacatc aggaacatat tacccttttg cttttaaaga
    12241 gaaagataaa cttaaaggat ttgaagtaga tttttgggat gaatttgcta aacgaactaa
    12301 ttgtaaagtt gaatgggtat taactgattt tagtggatta tttggattat tagaagctga
    12361 taaagcagat gttgtatctg ctcaacttac tgcaacacct gaaagagaga agaaatatga
    12421 tttttcagat gcttataact atagtggaac aaatattatt gttagagaag atgatactag
    12481 tataaaatca atagatgatt tagttggaaa gaaagtaggt gtgggtactg gagcagtagc
    12541 aaatgaaata ctaaaagaaa agtacccaaa tgatgaaata aaaatagtaa attattcaag
    12601 tgcaactctt aaaggaaatt atcaagacct agaaatggga agattagatg cagtagttgc
    12661 gcaggatgtt gaggctttaa tagctataaa agaacaaaaa ttaaatctta aattggtaga
    12721 acctccaatt cagttcggag cctgttcctt tgcgcttcaa aaaaatgaaa agggtgaaag
    12781 atggacaaaa gaaataaaca aagtaattga agatatgcat aaagatggga ctttgactaa
    12841 aatatctaaa gcctggctag gaaaagatat tactaaggag cctattaatg agtagtttta
    12901 attttgaatt ttgtctaaat atatttccat ttttgattaa agcattggga ataacaatac
    12961 taatatctat tattgcattt tttatatcaa tattattagg tgtaatactt gcatttttca
    13021 cacagacaaa atcaaaaatt ttgcaataca taactagagt gtacgtttca ttttttagag
    13081 gaacaccact tttaattcaa atatttttct tttactttgg atttccaatg gtattttctt
    13141 ttatgaaaga ttgttcccct tatttagcaa tagtaatttg tttaggtgta aattcatctg
    13201 catatatggc tgaaattata cgagcatcta ttgagagtgt tgataaagga caacaggaag
    13261 catgttatgc ttttgggtta agtaaatatc aatcaatggt taaaataatt ctacctcaag
    13321 cagctacatc tgcagtacct cctattgtaa gttgtacact agatataatt aaaggttctt
    13381 ctttaggtct aactatagga atacaagatt taatgggagt agctcaagta gaggctgctt
    13441 caagttttaa atattttgag atatatatgg taacgatact aatttactgg gcagtatcta
    13501 taatgttgag taatatacaa agcaaagttg aaaaaagaat aggaaaagca tattagattt
    13561 caatatttaa aaatgggatg atatagatat attatcactt gtaaataaat ttttaatttt
    13621 agaaaaacaa atttagtaat tctaaatatt gagaaaatat aatacaaaat gaactttata
    13681 atcaagttga aaaatggttt tttctattga aaaataaata aaattctatt gtaatttaat
    13741 atgtgacaaa agtttgtaaa aaacaacatt aagctggggg gacttatttt atgattttta
    13801 atatgaaata ttttttagaa ttatttccaa taataatgaa atcgttcaat gtaactgtga
    13861 ttttggcaat aagttcatta gtattttcat taattatagg tacaatagta gcattatcat
    13921 cttattacaa agttaaagta ttgaatcaaa tatgtaaagt atatgtatct atctttagag
    13981 gtacacctct tatgccacag ttattctttt tatattttgg attagcatat atgagcgatt
    14041 ttgttaaaaa tatggaccca gtatttgcaa catctatagt gcttagttta aatatgggag
    14101 cttatatgtc tgaaacgata agggcttcta tactttcaat tgataaaggt cagatagaag
    14161 cagcatatgc aatgggatta acaaatttac aaacaatgaa aaggatagtg ataccacagg
    14221 ctgtaagagt tgcactgcca tcattattca ataattttat agatttaatt aaagggtctt
    14281 ctgtagcttt tgttgttgga gtaaatgaca taatgggtgc tgctaaatca caaggagcgt
    14341 tgagttttaa gttctttgaa gtgtatggag cagttatggt aatttactgg tgtataataa
    14401 ctcctttagg gtgggggcaa aaaaaattag aaaagaaaat aagcaattat taagttatta
    14461 agaaaataca taaaagtatt tttaaataaa aaatggtgtg aggagaagag atatgataaa
    14521 aagaaatatt ataaaatgtt tagtggcagt tttatcgtta acagttttag ttactggttg
    14581 ttcaaaaaaa gaggaagtaa aggatgaaaa agttataact gtagcttcat ctaattcagc
    14641 tgacccatat tcttatgttg ataatggtga gcataagggt tttgaagttg acatgtggaa
    14701 agagattggt aaaagaagtg gatataagat aaaaatggaa ccaacaggtt ttagttctat
    14761 atttgggatg ttagattctg gtaaagttga tgtggcagcc aacttctttg gaatgtctaa
    14821 agaaagatta gaaaaatacg atgcttctat accttatggt tctgattctg tatgtatagc
    14881 tgtaaaagat ggaaacaacg aaattaataa acttgaagat ttaaaaggaa aagttgtagc
    14941 agtttcagaa ggttctcaag ggcaacaggt tgcagctagt gttaataaag ataatttatt
    15001 tgaagaaaag gtttacggtg atggaactaa tggtcttcaa gatttagatt taggaagagt
    15061 tagtgcatgg attgacgcag agcttactgt tataggagac gctaaaaaag ctaatatgaa
    15121 ggtaagagta ttagatgaaa aattatcagt tactaatata gcatacttct ttaagaaaaa
    15181 tgatgaaaaa tctaaaacta taaaagaaga tgtaaacaaa gcaatagaag aaatgcttgc
    15241 agatggaaca gtgaaaaaaa tatctgaaaa atggtttgga atggatgtaa gtgctgatat
    15301 acaaaaataa atactttaaa attaaaatat aaaactgtga taactataga taagtatact
    15361 aaatttatct atagttatct gtgtattaca atgtatttag attagtcttt ataaattaaa
    15421 atgagttatg gaggtcttgc aaatgattga aactaaaata aaatccattg cactaaaaaa
    15481 tagagaaaaa attataaaaa taagacgaca gatacacagt aatccagagt tagcatttaa
    15541 agaatttaaa acatccaaac ttataaaaga agagctaaat aaacttaata tagaatacat
    15601 agatgttgct ggcacaggag tattagctac tataaaagga aaaaataatg gtgggaaaac
    15661 tatattacta agagcggata tggatgccct tccaatcaaa gaggaaaatg atttagaatt
    15721 taaatcaata aatgataata tgcatgcttg tgggcatgat gcacatgttt catggttgtt
    15781 aggaacagca atgattttaa atgacataaa agaagaattg aatggaaatg taaaattact
    15841 atttcaacct ggcgaagaaa aaggtggttc tgatattgta attaaagaaa atgtacttga
    15901 aggtgtggat gcattagcga ctggtcattg ttggccaact attgaatcag gaaaaattgg
    15961 aatcgctaga aattgtgcta tggcagcgac taatactttt gaaataacaa taattggcaa
    16021 gggtgggcat ggagcagagc ctcataattg tatagaccca attgcagttg gaaatgcagt
    16081 atattcatcc attcaacaga tagtttcaag aaaaattaac ccagttatac ctgtagtagt
    16141 gtctgtttgc tcttttaatt ctggtgtttc taaaaatata ataccagatg tatgcacact
    16201 tcaaggaacc attagagcga taagtcaaga aaaagtaatt gaaataagta aaattctaga
    16261 aaatatagta agaggtgtct gtaaatcaaa tggagcagat tgtaagtttg aaaagagcat
    16321 gggaggggat gctgttataa atgataaaga tatgattgag ttgggaaaaa agagcgcttg
    16381 taaaatactt ggatatgaaa atgttgaaat gattgatttt cctgcaatga cgggtgagga
    16441 ctttgctatt tatatgaaag aaagacctgg tttgtttatg tatataggcg taggaagtga
    16501 agaaaaaaat ataaattaca gattgcataa taacaagttt gatatagatg aaaaatgtct
    16561 tagcgtagca tcttctttat tctcacaact tgcagtagat tatttatgtc aactatagag
    16621 tacattcata aaaatatatt tagcctattt ttaaatttaa tgctagtata ttaattttaa
    16681 tgtagaaaat attatttatt atatttattt aaaaaggtgg ataacaatga taaaagtaga
    16741 aaatttacat aaaagtttta aagggacaga agttcttaaa ggcataaatc tagaaataaa
    16801 tcaaagtgaa gtagtagcta tacttggccc atctggaaca ggtaaatcta cattgcttag
    16861 atgtttaaat tatctagttg aacctacaaa aggaaaaata atgattgggg atgtaaaggt
    16921 agatgtagaa aggacaacga aaaaagatat agctaattta agaaaacata catctatggt
    16981 gtttcaaaat tataacttat ttaaaaataa aacagcttta gaaaatataa tggaagcatt
    17041 aatagtagta cataaaaagg gtaagcaaga agctagagaa atatctttaa aactattaga
    17101 taaagtaggt atgttggata ggaaagattt ttatccatca aaattgtctg gtgggcagca
    17161 acaaaggata ggtatagcaa gagcgatggc agtaaatcca aatgtaatat tatttgatga
    17221 gccaacatct gcacttgacc cagaacttgt tggagaagtt ttaagcgtta taaaatcgct
    17281 tgcaaaagaa ggtataacga tgcttattgt aactcatgaa ataaattttg caaaagaagt
    17341 tgctgataaa attatattta tggataaggg cgtaatagct gaagaaggaa ctcctgatga
    17401 aatatttaat aatcctaaaa atgaaagaac tgcaaagttt ttaaatatca ttaaaaaaga
    17461 agaagtattt agttaaaagt atataaatta agtattagaa gatatgtaag atatcctcat
    17521 taaatttata agttagataa taaatttaat tggagtatct ttttattatt agatttatta
    17581 tttaatttaa aattagaaaa gtagctattt gaaaattact tttaaaagta tatcaaaata
    17641 tcaattacat gaaaaaataa tatttgacaa aatatcatat gtgtttacaa aattaacttg
    17701 atggaatgat aaagtatagg aattacaatg agtatactaa aactttatat taaagtacaa
    17761 attattaaat ttgaaaataa ttaagtaata ttatatatat ttttttatat tgtttgtttt
    17821 attaaaatc
//
LOCUS       DBGJFK010000083        17046 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.083, whole genome shotgun sequence.
ACCESSION   DBGJFK010000083 DBGJFK010000000
VERSION     DBGJFK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17046
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.083"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..860
                     /locus_tag="ACOIAP_003101"
     CDS             <1..860
                     /locus_tag="ACOIAP_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase dimerization domain-containing
                     protein"
                     /protein_id="HGZ2639978.1"
                     /translation="NAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNV
                     GANYLREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVA
                     QGAAMMTETEMEYKVTDGIYDYIPNQCLTDLVYNNMVFVGCPKTTPEEEEFAKKLCDT
                     LTREERLGVATSFQNDKSIVESYIHKGIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMA
                     AWPVGIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSL
                     DGQKFKPLV"
     gene            895..1119
                     /locus_tag="ACOIAP_003102"
     CDS             895..1119
                     /locus_tag="ACOIAP_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015759013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HGZ2639979.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(1442..1840)
                     /locus_tag="ACOIAP_003103"
     CDS             complement(1442..1840)
                     /locus_tag="ACOIAP_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsmA family protein"
                     /protein_id="HGZ2639980.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKNDEE
                     KKKFFHKFSIVVWTIWLIPYFIGMFIGMAG"
     gene            complement(1843..2286)
                     /locus_tag="ACOIAP_003104"
     CDS             complement(1843..2286)
                     /locus_tag="ACOIAP_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGZ2639981.1"
                     /translation="MILLKTNYDCFRIAMLLKELYSKTMYTVEENFKENGLTHQQIIV
                     IKLIAHNQELTISQLCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTT
                     GFEFATNFKIKMQESFDDIFKNCDEKELSDLVKNLRTILAKVKER"
     gene            2605..3591
                     /locus_tag="ACOIAP_003105"
     CDS             2605..3591
                     /locus_tag="ACOIAP_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639982.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYNQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRVICKLGTITNCIPSFWVALVLILVFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLVLSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEAAI"
     gene            3575..4486
                     /locus_tag="ACOIAP_003106"
     CDS             3575..4486
                     /locus_tag="ACOIAP_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2639983.1"
                     /translation="MKPQYSDFEIVGENYILVAKDEHVETKKNLFRKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASEFVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            4599..6167
                     /locus_tag="ACOIAP_003107"
     CDS             4599..6167
                     /locus_tag="ACOIAP_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2639984.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADKPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGILPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQVTPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNHTIDKI
                     LQKARETENKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            6242..7267
                     /locus_tag="ACOIAP_003108"
     CDS             6242..7267
                     /locus_tag="ACOIAP_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639985.1"
                     /translation="MEHLLEVNNLSVNFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSNLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLHPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPKIDVPVRVNC
                     GRVISNE"
     gene            7260..8204
                     /locus_tag="ACOIAP_003109"
     CDS             7260..8204
                     /locus_tag="ACOIAP_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2639986.1"
                     /translation="MNREKMLEIKNLKQYFHLDKNTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIVRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGIYKNKTDRMNKVYEMLNLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRTRIEYNSN
                     VYDCSNEKSLSWIEVSDGHFVYSSKADINKYQQNLKVV"
     gene            8564..11221
                     /locus_tag="ACOIAP_003110"
     CDS             8564..11221
                     /locus_tag="ACOIAP_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2639987.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQNELLGIKKGTTVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAVLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERIELIKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLKYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHRIEYFVFTSLG
                     EEEVINYNDINIINAVNTNINKSVEMNITDASLFNNVKFKNMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGNCNAISFDL
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVMVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMNRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVALINEQRINIRGIDY
                     ISKKDIDKDKSINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKMLNYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            11435..12064
                     /locus_tag="ACOIAP_003111"
     CDS             11435..12064
                     /locus_tag="ACOIAP_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2639988.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAIIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEIMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEQYNSEEVIDTAFRFNHWQY"
     gene            12182..12508
                     /locus_tag="ACOIAP_003112"
     CDS             12182..12508
                     /locus_tag="ACOIAP_003112"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGZ2639989.1"
                     /translation="MNILLVCANGASTGVLVEKMKNFCSEHEKLKTKTINIEATSFEN
                     LKSYIQANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            12524..13813
                     /locus_tag="ACOIAP_003113"
     CDS             12524..13813
                     /locus_tag="ACOIAP_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGZ2639990.1"
                     /translation="MEALQNNLRKFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVIAQLVVCGQVIDGALDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVLGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSLNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATALDDDSFDF"
     gene            13837..14166
                     /locus_tag="ACOIAP_003114"
     CDS             13837..14166
                     /locus_tag="ACOIAP_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGZ2639991.1"
                     /translation="MVPEIEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            14314..15642
                     /locus_tag="ACOIAP_003115"
     CDS             14314..15642
                     /locus_tag="ACOIAP_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HGZ2639992.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKNPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLESRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TKERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGEIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPELN"
     gene            16066..16920
                     /locus_tag="ACOIAP_003116"
     CDS             16066..16920
                     /locus_tag="ACOIAP_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HGZ2639993.1"
                     /translation="MKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKEVP
                     SKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDIEE
                     VEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCNKI
                     IKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLNTI
                     KEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEEEE
                     EKYRRIFK"
BASE COUNT         6778 a         1884 c         2990 g         5394 t
ORIGIN      
        1 taaatgcacc ttggagaggt ggaagtctag caaacttatc tgtaaaattt aaatttaaag
       61 gtataacagc ccatgcagct caagctcctc ataatggtag aagcgcactt gatgctgttg
      121 aaattatgaa tgttggagct aattatttga gagagcatgt tattgactct ataagaatgc
      181 actatgttat aactaatggt ggtggaagac ctaatgtagt tcctggcttt gctgaaagtt
      241 ggtactttat tagaggaaaa aaagcaaagg acgcagaaca cgttcttgat agattaataa
      301 aagtagctca aggagcagca atgatgacag aaactgaaat ggagtataag gttacagatg
      361 gaatatatga ttatatacca aaccaatgtt tgactgattt ggtttataat aatatggttt
      421 ttgttggatg tcctaaaact actcctgaag aagaagaatt tgcaaaaaaa ttatgtgata
      481 ctcttactag agaagaaaga ttaggtgtag caacatcatt ccaaaatgat aaatccattg
      541 tagaaagcta tatacacaaa ggtatagttg atggagacaa agataaagga ctagctggtt
      601 ctactgatgt tggagatgta agttatgtta taccagtggc tcaatttgca atggcagcat
      661 ggcctgttgg aattgcaagt catacatggc agtcatgttc atcagcaggt tcaaatatag
      721 gattttctgc tatgataaat tcagctaaag tattggcttg tagtgcctat gatgtattta
      781 tggatactaa aattattgat gaagcaaaaa tcgaatttga taaatcatta gatggacaaa
      841 aatttaaacc attggtataa ttttggtaat aaaatatttc tggggggaat agctatgaga
      901 gaaaaagttg aaaaagtgct tgaagaaaag ataaaaccag tattgcaaag agatggtgga
      961 gatgtagagc ttatagatgt aaatgaaaat ggtgtagttt tagttagact acaaggagca
     1021 tgtagtgggt gtccaggagc gactatgaca atcaaagcta ttattgaaaa tgttttggtg
     1081 agtgaagttc caggagtaac tcaagtatta ggtgtttaac agttagagtt tattaaatat
     1141 atgttataca taaatattta ataaagaagt atgaaaaaaa tagtgaaacg ttatatataa
     1201 aaatatgaaa aagataataa aacattatag aaacaattaa atattccata tagatatgaa
     1261 aaattgtgag aaaataataa aatattatag gaataattaa atattctata ttaggtatga
     1321 agaaatatga aagacataat gaagtattat agataaatat gtaaaagtgt gaaagaaagg
     1381 tgtagataaa tttgttttat acaaatttac ctaccatatt tcttacacac tttttatttt
     1441 gctatccagc cataccaatg aacataccta taaagtatgg aattaaccat atagtccata
     1501 caactatact aaacttatga aagaattttt tcttctcctc atcatttttg tataggacaa
     1561 aagtagccca acttgcatga aaaagcataa gcacaattgc aagaagacct gtaatactat
     1621 gaaggttttg tgataaagcg gattttactt caaaagtatg gctgttggct atgttactca
     1681 ttgtaaatgt tcctaaagtg tcaaatataa aaccaagcca aaatataatt acatgtttct
     1741 ttttcaaaat tttagccttt ctttctccaa atacacctat agtgtagaaa attaaagctg
     1801 atgttataaa tactattgca agtattaatt tataattcat aattatctct cctttacttt
     1861 tgccaatata gttctaagat tttttactaa gtcactcaat tctttttcat cacaattttt
     1921 aaaaatatca tcaaaacttt cttgcatctt aattttaaaa tttgttgcaa attcaaatcc
     1981 tgttgttgta aacttaacgt atgtatttct tttatcatta gatttcttga atttttctat
     2041 atatccaatc tgttctaatc tgctgattat gcctgaaacc gtacctttag ccaaagacat
     2101 ttcatcacaa agttgtgata ttgtaagttc ctgattatga gctattagct ttataactat
     2161 aatctgttgg tgtgttaatc cattttcttt aaaattttct tccactgtgt acatagtttt
     2221 agaataaagt tcttttaaga gcatggctat tctaaaacag tcataattag ttttcaataa
     2281 aatcacctct taaatggttt gcatacaaac taaatataat atacttttat tatatagtca
     2341 acctaaaatt ttataatttc atataaaata atgaagaata gaacataaaa attttatttt
     2401 agatataaat aaaataattt gatgaaattt taacaatttt taaaaagttt gtttacacag
     2461 ttaataaatg atgctaaaat taactcatag ataaatattg aaaatttaaa tttgtttaat
     2521 gataatagaa ccacgaaggt tttaacgtta ctttacgttt gcttttatgt ggtttttttt
     2581 attgcaacaa aggggggttg gggtttgtta aaggatatac tgaaaaagtt gttgcagttt
     2641 attttagtaa tgtttttatt atcttttatt gttttttaca tggcaagact tgctccagga
     2701 gacccattaa tctcttatta tggggatgga gtagaaagaa tgagtacaca agaaaaagaa
     2761 aatgctatga aaaaacttgg tttagatgaa ccaatataca atcagtatat aaagtggatt
     2821 tcgaatgcat caaaaggaga atttggaatt tcatttaaat ataaacaaaa tgttacttct
     2881 gttataaatg atgtctatat aaacactata atattaggtg gttcaggata tatacttacc
     2941 tttgtactag ccttattgtt aggaatattt tgtacactac atgaagataa gctcattgat
     3001 agagtcatat gtaaattagg aacaataacc aactgtattc catcattttg ggttgcttta
     3061 gtactcatac ttgtatttag tataaactta agtatacttc caagtagtgg cgcttattca
     3121 atgggagaag aatccagtat attaagtaga atatcacatt taattttacc tcttacagta
     3181 cttgtattga gccatttatg gtattacaca tatatgataa gaaataaatt actagaagaa
     3241 ataagagaag attatgtact tctatgtaaa gcaaaggggt taaataatag aactattgtt
     3301 tttaagcatt gcctgagaaa tataatgcca tcatatatca gtataatggc tatttcgata
     3361 cctcatatac taggcggaac ttatgtagtt gaaaaagttt tttcttatcc tgggctagga
     3421 acactttgtt ttgaaagtgc aaagtatcat gattataata tgttattagt tttatgctta
     3481 ataacagggg ctttagtagt atttgggaat atgttagctc aaattataaa caataaaata
     3541 gaccctagaa tgaaatatga tagaggtgat actaatgaag ccgcaatata gtgattttga
     3601 aattgtagga gaaaattata ttttagtagc aaaagatgaa cacgtagaaa caaaaaaaaa
     3661 cttatttaga aaaattaaag aattaccata tatatcaatt attattttat caattatagt
     3721 aattggaagt gtattctcat cttttataat gacacatgag ccgacatata tggatttagc
     3781 aagctctaat ttagctccaa ataaaacttt tttatttgga acagactcaa tgggtagaga
     3841 tatatattct atgatatggt atggaggaaa aatatcttta tttataggat tattttccac
     3901 tgtaatatca actgttatag gaattgttta tggtagtata agtggttcag catctgaatt
     3961 tgtagatgat gcaatgatga gatttacaga aatcatactt agtatacctt caatattaat
     4021 tataatattt gtacaagcta tacttggaaa ttcaaatcca gtatctatgt ctatagtaat
     4081 aggtataaca agttggatga atatatctaa gatagtgaga acagaggtta gacaaataag
     4141 aaatagtgaa tacatactag cagctaagag tatgggagga ggattcttct atgtattaaa
     4201 gcaacattta cttccaaatt ttgtggcatc aataatgttc atggttgtaa caaatatagg
     4261 tgcagctatt ggtactgaat caacacttag ttttttagga attggtttac caatagaaat
     4321 tgtttcttgg ggaagtatgt tatctttatc agaggaagca ttactttcaa acagatggtg
     4381 gattatactg attccgggta tatttttggt taccacattg gtgtgtataa caaatatagg
     4441 taattacata agaaagaata ataataaaaa atctagtaat ttataaatca gcatttgagt
     4501 ataaaataag caaatactga ggtatttgaa atatctattt aaataaatgg ggtcaaagct
     4561 ttgaaaaata ttttataaaa agcaaaaggg ggagcatcat gaaattaaag aagttaaaag
     4621 ttttaagttt agtaatgata cttagtctaa tggcaggttg ttctagtgga ggagacaaag
     4681 ataagaaagc agataagcct aaagatggaa aggtacttgt ttatggaagt aatgactata
     4741 caagtataaa tcctgcacta tatgaacatg gagaaataaa ttcattaata tttaatggat
     4801 tgacagctca tgatgaaaac aataaggtgg ttccttgtct agcaaaagat tggaaatttg
     4861 atgaggcaac aaatacatat acttttaatt taagagatga tgttaagtgg catgatggag
     4921 agaaatttac agcaaatgat gttaagttta caatagaaac tataatgaat ccagacaatg
     4981 cttctgagat agcatcaaat tatgaagata taacaaaaat tgatgtagtt aatgataaca
     5041 ctataaaaat tactttaaaa gctccaaata cagcaatgct tgattattta acagtaggaa
     5101 tattaccaaa acatgcttta gaagggaagg atatagctac tgatgaattt aatcaaaagc
     5161 caataggcac tggtccattt aaacttgaaa aatgggacaa aggtcaaagt ataacacttg
     5221 ttaagaatag tgattatttt gtaaaagaac caggattaga taaagtagtc tttaagattg
     5281 ttccagatga taaggctaag gcaatgcaat taaaatcagg ggaattagac ttagctcaag
     5341 taacacctaa agatatgtct aactttgaaa aagacgaaaa gaattttaaa gtaaatataa
     5401 tgaaaacagc cgattataga ggtatattat acaattttaa ttctaaattc tttaaagata
     5461 aaaaagctaa aggattgcca aatgctttaa gttatgcaat agatagaaaa gcaatcgttg
     5521 atagcgtatt attaggacat ggtgttccag catattcacc tttacaaatg ggaccatata
     5581 ataatcctga tatagaaaag tttgaatata atccagaaaa agctaaacaa gaaattgaaa
     5641 agctaggttg gaaattaggt tctgatggaa tatatgaaaa agaaggtact aagttagctt
     5701 ttgagataac agcaggtgag agtgaccaag ttagagttga tatggctaag atatgtgcac
     5761 aacagttaaa agaaattggt gttgatgcta aagctgtagt tgtaactgaa acagactggg
     5821 ctaatcaaga tgctcattta ataggttggg gaagtccatt tgacccagat gaccatacat
     5881 ataaagtatt tggaacagat aaaggtgcaa attacagtgc ttactctaat catactatag
     5941 ataaaattct tcaaaaagca agagaaacag aaaataaaga tgaaaagtta aagttatata
     6001 aacaattcca agtagaaatg actaaggata tgccttacac atttattgct tatatagatg
     6061 caatatatgt tggaaaacca aatatcaaag gattaacacc tgatacagtt ttaggtcatc
     6121 atggtgtagg tatattctgg aatatagctg actggacaat tgaatagtat tgaaattaat
     6181 tagaaacctt agggataaaa gtatatccct aaggtttgaa tagcataggg gttgatggtt
     6241 tttggaacat ttattggagg ttaataatct atctgtaaat tttaaagtag aagaaggaga
     6301 agttcaggct gtaagaaacg tgtcttttaa tctgaaaaag ggtgagacat tagctatagt
     6361 tggagaatct ggttgtggga aatctgtact atgcaagagt ttgatgagga tactcccata
     6421 caatggatat attaaaaatg gagaggtttt acttaaatca agtaatttgg ttaagaagtc
     6481 tgaaaaagag atggaagata taagagggaa aaatatatca atgatatttc aagaccctat
     6541 gacatctctc aatccaacta tatcaatagg aaagcaaatt gcagaagctg taatcattca
     6601 tcaaggtata agtaaaagtg aagcaaaaaa gagggccata gagcttattg aattggttgg
     6661 aatagataat cctgagaaaa gatttaaaca atttccacat catttttcag gtggaatgag
     6721 acaacgtata gtaatagcta tagcacttgc ttgtaatcca gatgtattga ttgctgatga
     6781 acctacaacc gctttagatg taactataca agctcaaata attgatttaa taaaggattt
     6841 acaacataaa ataggtttgt caataatatt tataactcat gatttaggag tagttgcaac
     6901 tattgctgat agaatagcag ttatgtatgc aggaaagatt gtggaaatag gaactgtgga
     6961 ggatatattt tatgacccta gacatccata tacttggggg ctgttaggtt cattacctac
     7021 tttagattcg caggatgact atttgtataa tatacctgga atgcctccaa acttattgca
     7081 ccctccaaaa ggagatgctt ttgcaataag gaataaaaat gcacttaaaa tagattatga
     7141 aaaagagccg ccaatgttta aaatcaatga tacacatagt gcagcaactt ggttattaca
     7201 tccagatgca cctaaaatag atgtaccagt tagagtaaat tgtggaaggg tgatttctaa
     7261 tgaatagaga aaaaatgctg gaaataaaaa acttaaagca atattttcat ttggataaaa
     7321 atactactgt aaaagcagtt gatgatataa gttttgatat atataagggt gaaatatttg
     7381 gattggtagg agagtcgggt tcaggcaaat ctacaactgg taagactata gtaagactac
     7441 atgaatctac tggtggagaa gtaatttaca aaggaaattg tatatccgat aagaagacat
     7501 acaaatttat aaaaaaagat gtaaacaaaa gtatgcagat tatttttcaa gattctactt
     7561 catcattaaa tccacgtatg acaattgcag atataatttc agagccacta aaaattcaag
     7621 gtatctataa aaataaaaca gatagaatga ataaagtata tgagatgcta aatctagtag
     7681 gacttgatag aagttatgca aataagtatc catctgattt ttcgggtgga caaagacagc
     7741 gtattggcat agcacgagct ctttcagtag acccagaatt tataatagct gatgaaccta
     7801 tagcttcttt ggatgtgtct atacaagcac aaatagtaaa tttatttaag aagttacaac
     7861 aagaaaagaa tttgacttgt ttatttatag cccatgattt atctatggtg agacatatta
     7921 gtgaccgtat aggagttatg tataatggaa aattagtaga actggcagat tcaaatgaat
     7981 tgtataataa tcccattcat ccatatacaa aatcactact ttctgcaatt cctgttcctg
     8041 accctagata tgctaagtca agaactagaa tagagtataa ttctaatgtg tatgattgct
     8101 caaatgaaaa gtcactaagt tggattgagg tttcagatgg acattttgta tattcttcta
     8161 aagctgacat aaataaatat caacaaaatt taaaagttgt ttagtataaa aaaacttgaa
     8221 catgtattta tttgaaatac aaactaaaac cctatttttg gataaatttt aaaactactc
     8281 caagataggg ttttttattt acacttttca aatataataa attcaaatat aataaaatta
     8341 aaaacaagta aagtatattg ttaagaaagt accataaaat taaaaaatag tattttagaa
     8401 aaaattatca ataaccttat tttttctaca ataattttat ataatttaaa ataagacaag
     8461 tttgataaat tataatctta gttaaagaat aagagtttat taaaaaacaa agtgagtata
     8521 aggattttag ttaacaaaat attataatgt aggggagctt gtaatgatat ataaaaaaga
     8581 taaagtaatg aaagttttag aatcatcata tagggaaaat gaaaaaggga ttacagctaa
     8641 ccaattatca gaaaagacag gaattgcaag aaacaatata agtacatatt taaaccagct
     8701 attcaatgag ggtatggtta caaagataaa aggaagacct gtgtattata tccctgcaaa
     8761 tcttaacctt aacaagaatg aattgcttga tacacaaaat gagttgcttg gcataaaaaa
     8821 aggaacaaca gtagaaaaca agataaaaaa agatagtttt gaaacactaa taggtaaaga
     8881 acatagttta agacctataa tagaaaaatg taaggttgca gtgctttatc ctacaaatgg
     8941 acttcatacc attatctatg gagaaacagg agtaggaaag agtatgattg ctagatatat
     9001 gtatgactat tctatagata gtggaattag gaaaaataaa gctcctttcg taacatttaa
     9061 ttgtgctgat tatgctaata atgcacaatt acttatggga catatctttg gagtagaaca
     9121 aggtgcttat acaggtgcag aatcttccag aaaaggactt ttggaaattg caaatggggg
     9181 tatattattt ttagatgaaa ttcatagatt accagcagaa ggtcaagaaa tgttgtttac
     9241 ttttatagat aaaggaacat ttaaaagact aggagatgca acgaaagaaa gagagtctaa
     9301 ggtattaata atatgtgcta ccacagaaaa tccgacatca acactattag atacattcaa
     9361 tagaagaata ccaatgaaaa tagaaatacc atcactgaga gataggacaa tgattgaaag
     9421 aatagagtta atcaaaaatt ttttcaaaga agaatcaaaa agcatttcta tttcaataaa
     9481 agtacataaa gaaataatta aatcactatt actttatgat tgtaaaaata atgtaggtca
     9541 acttcaaaat gatataaaat tagctgttgc aaatggatac ttaaagtata aaagagataa
     9601 taaagaacca gtttatatag agaaaaaata ttttgataaa tctataaatg aagtgagtga
     9661 tgattataga gagaagtcta ttaaagcaga tgaagttata acacatagaa tagaatattt
     9721 tgtgtttacg tcattaggag aagaagaagt tattaattac aatgatataa atattattaa
     9781 tgcagtaaat actaatatta ataagtctgt agaaatgaat ataacagatg cttctttatt
     9841 taataatgtt aagtttaaaa acatgtgtga atcaataaga caaattatta aagaagatga
     9901 agaaatagat ataagtgaat caatatttaa gtcaatggca atttatataa aaagcgtatt
     9961 ggataaaagt agctctacaa acaacataga tttgaatcaa attagaagaa ataatagaag
    10021 tgaatttaaa acagcattaa aaatagttgg aataattgaa aatgaatttg atttattttt
    10081 atctatagaa actgtagcat atattacatt attcatagta caagctaaac aagatgagca
    10141 aaataaaata gtgaataaca ttaatattat agttgctatg catggagaaa ctacagcaag
    10201 tagtatggtc aaagcagttg gtgatattat tggaaattgc aatgctattt cttttgattt
    10261 gaagttagat aaaagctatg atgaagttat tgtagatttt aaaaatttaa ttaataatat
    10321 agacaacaag gatgtactac tatttacaga tatggggtca ttaaactcct ttgatgaaat
    10381 tataaagaaa gaaaaaaagt gtggagtaat ggtaattcct atggttacaa cattaactgt
    10441 gttagaagca gttcagaaag ctaatatggg actaccttta aatgatgtat acaactctat
    10501 tactaacacg agaaagtact attttggaac taatgaaatt caaaataaag aaaatctgtc
    10561 taaaacaatt attatagcat cacacgtttc agaaggtgta gataataaaa caagaaaaat
    10621 attagaagaa aagatgaata ggtatttaga tggaatagat attatatctg tcccatataa
    10681 aacagaaaaa gacttaagtt taaatatcac aaaacttaaa gaaagtagta atattgtagc
    10741 attaatcaat gaacaaagaa ttaatattag aggaattgac tatattagca aaaaagatat
    10801 agataaggat aaaagtatca ataaattaaa aaatattata aagataagta taggttatga
    10861 tgatgtagtt gaaggtctaa agacatcctt aaaaagctct aattataata ggatatttaa
    10921 agatataaaa tatgtgtctg acgaattgtt tttagtattt aacatagaaa agaaatatga
    10981 taaagtaatt ggacttatga tgcatttagc ttttatggta gatggattga ttggaaatac
    11041 tagagaaatt gaaaagcttg ataaagaaaa aatgcttaat tatcacaaga gcttaagtaa
    11101 aataaaagat atagtatctc aattagataa aaaatataat atagaaatta atgaaaaaga
    11161 gtgttatcaa atattgttaa tattagaata tgcagaaata atcgaaaaag attaccaatg
    11221 agtataaaaa cttatttggt aattttttta gtctaaaata atattaatat tagacacata
    11281 tgaatatact tagacaaagt atctaagttt ttgtgctaaa aatgactgaa ataacaccgt
    11341 tttaaagtgt ctaaaaaaat tggcataata cttgcttata ttactaaatt agtaatataa
    11401 ataattaaaa tttaaataaa aaggagtaaa taatatgcaa gataaaatat taagagataa
    11461 aaaggcaaat gacccatggg caagaatgac tacaagaaac ggatttagtg cagacgaaat
    11521 aatatcatca tttcaaaaag ctataagaag aaatatggtg gaagaagctt gtgaatttgc
    11581 ttatgaacta tatatatcat caccagaatt agaagataag ctatggagaa gaatacttac
    11641 aatatcagtt gaagatatag gaatggggga cccatcagct ataataatca taaataattt
    11701 aaatcaagta agaaaggaat attcatatgc agatggagat agacctctat ttttcataca
    11761 tgcaataaga tatctttgtg catgtgagaa agatagatca agtgacttat taaaaaatat
    11821 aattataaaa ggatttgcaa tgggtaaagt tccagaaatt atggacgtgg cacttgataa
    11881 acatacatat agaggattag aaatgggaag ggattcattc cacttcttaa atgaagctag
    11941 catagtaata ccagaaaaag aagtagataa tgattataaa gaaagatact taaaaatatt
    12001 agaacaatat aattcagaag aagttataga tacagctttc agatttaatc attggcagta
    12061 ttaagaatta gagtaaatat taataagaat taaaataaaa attaataaga attagagtaa
    12121 taattaatta ataaaaaatt agaaaataaa agaggttaga tattgcagga gggtaattat
    12181 tatgaatatt ttattggtat gtgcaaatgg agcttcaaca ggggtgcttg tggaaaagat
    12241 gaaaaatttt tgtagtgagc atgaaaagtt aaaaactaaa actataaata tagaggcaac
    12301 atcatttgaa aatctaaaat catacattca agctaatgat acagatgtag tacttgtagc
    12361 accacaaatt aggttcaagg aagatgatgt agttgaagct tgtaaaaatt acaaaatagc
    12421 agttggttta atagatacta agcattatgg tcgtatggat gctccttctg ttatgaagtc
    12481 ggcaatcgaa ttatataaaa atagataatt ggggggaata aatatggaag cacttcaaaa
    12541 taatttaaga aaatttcttc ttccaatagc acaaaagatt gaaaaacaaa ggcatcttca
    12601 agctataaaa gaaggtatga taagtattac cccaataata attgttggtt ctttaagtat
    12661 gttatttatg gcattaaaca atatgttacc tgaaggaagt gcaaaaacat tattatctga
    12721 aaatatggat acattactta tccctaataa atttactatg agtttattat ccatatattc
    12781 agcatttttt atagctcagg cactagctaa aaaatataat cttaatcatg tagaaatagg
    12841 tatgacagca gttatagcac aacttgttgt atgtggacaa gtaatagatg gtgcattgga
    12901 tacaagttat ttagatgcac aaggtttatt tgtaagtata ttagtagcac ttttagtagt
    12961 tgatattact aaatttatga atgataaaaa tctcgtaatt agatttccaa aagaagtacc
    13021 tagtgtagta aataaaagct ttagaaactt aacaccaatg atagtatgta taatgttatt
    13081 tacagcaata gcagcaataa ctaaaaatgt cttaggtcaa ccgttaccag ctattataat
    13141 gaatttctta gcaccagcta taagcagtgt agataatgtt tttgcagtaa ctataatact
    13201 atttataact caattattat ggttctttgg acttcatgga gcagcaataa cttcaagtat
    13261 atggatgcca atagcagcta catatatggc agaaaatgca acactaatag ccgcaggagg
    13321 agacccaaaa tatgtattta caataggttt ttactatggt ttcttgcaag taactggttc
    13381 gggaataact ttagggttag tgtaccttat gtcaagaagc aagtgtaaga gtttaaatag
    13441 tatgggaaaa gttgtgattt taccatcatt atttggaata aatgagccag taatatttgg
    13501 aacaccaata gttatgaacc catatatgtt tgtaccattt gtatttggac ctgtattggt
    13561 tggagcactt aactttatgg cattaaaggt aggattagta ggattaccta ttgcagaacc
    13621 accaggcttt ttacctccag gggttgcagc atttttaatg acattagatt ggaaggcaat
    13681 tgtattagta tttgcaagta taatacttat gaccttgata tattatccat tctttaagat
    13741 aatggagaag gaagaattaa ataaaaatgc agaattagct acagcattag atgatgatag
    13801 ctttgatttt taacaagtca ttagaaggag aaggatatgg tacctgaaat agaagaaaaa
    13861 gtatttagta taatatcaga agcaggagat gctaaaagtg atgtaatgat gtctcttaaa
    13921 gaaataaaaa aaggtgacta caacaaagca aaacaccttt taaattcagc ttcagaaaaa
    13981 atacaaacgg catcaaaaca tcatttagaa ttactatcaa atgctatgaa tagtgaagat
    14041 agtggaactg attttttagt tgtgcattct gaagaccatt attcaaatgc attatttgct
    14101 cattctttag tatctgaact tgtagatata tttgagatga tggacccaag aattaataag
    14161 aattaaattt cttgtaaata gtgcttgaag tttggctata gtttattaaa ttagtagatt
    14221 taataaatga actccctttt actttaaagt actagtattt ataaatttat ttataaatac
    14281 agtaaatttt taaatagaaa aggagatatt attatggaaa aattttcagt agtaatagct
    14341 ggaggaggaa gtacatatac cccagaaatc atattaatgt tgctagataa cttagatagg
    14401 ttaccattaa gagcaattaa attatatgat aatgatgaag aaagacaaaa taaggtagct
    14461 aaagcttgtg aaatactaat aaaggaaaag aatcctaata tagagtattt agcaacaaca
    14521 tgccctaaag aagcttatac agatgtagat ttttgtttag ctcatataag agttggaaaa
    14581 cttgaaatga gagaattaga tgaaaaaata cctctaaaac atggggtagt tggtcaagaa
    14641 acttgtggac caggtggaat agcttatgga atgaggtcta tagaaggtgt tcttgaaaac
    14701 atagactata tggaaaagta ttctccaaat tgctggatgt taaattattc taatccagca
    14761 tcaataatag cagaagctgt tagaaggtta agacctaatt ctagggtgat aaatatttgt
    14821 gatatgccaa taggtatgga acacaatata gcaaggattg cagggcttga atctcgtaaa
    14881 catatggata taaggtactt tggattaaat cactttggtt ggtatacttc gattaaagat
    14941 aaaaaaggaa atgaactttt accaaaatta gtagagcata taaaagaata tggttttata
    15001 aatggtgaag aaggaatgaa aaatgacaag aaagatagtt ggtttgaaac taatttattt
    15061 accaaagaaa tagtaaagac agatttaacg acaataccaa gcagttactt aaaatactat
    15121 ttatttccag attatgttgt aaatcattct gatgtaaatt atactcgtgc caatgaagtt
    15181 attgatggaa gagaaaaaga agtttttggt tcatgtgcat tgatagaaaa gcaaggtcat
    15241 tctaaaggta gtgggcttaa gataggaata catgcagagt ttatagtgga tttagctaca
    15301 gctctagctt ttaatactaa agagcgtatg ttattgatag ttcaaaataa tggagctata
    15361 gaaaatatac aagatgatgc tatggttgag attccatgta tagtggggaa agatgggtat
    15421 gaaccattat caatagggga aatcccaaca ttccaaaaag gtctaataga gcaacaatta
    15481 gcagttgaaa aattagtggt tgatgcttgg attgagaagt cgtataataa gttgtggcaa
    15541 gcacttatgc tatctaagac agttccgagt gcaacagttg caaaagaatt actagatgat
    15601 ttaatagaag caaacaaaaa ttattggcca gaacttaatt aaaaataata tattttttaa
    15661 agttcctaca gtttagtaca tagcatagtt aatgtatttg taggaacttt atttatgatt
    15721 ttataagttt gtctatgaca atcttatttc ttcaagactt gtaaataatt tgttatttat
    15781 agtattaata aacttgctaa acaagtagta tccgtattta cagatgatat acaagtagca
    15841 aatatagtgt attttacagt taggatggta ggatttagtt acttgttagt tggattaaat
    15901 ttatgtacaa tagtttactt caatcactag aaatagtttg agaagttgta taataaaaaa
    15961 tttacacttt taacaggatt tatgtaggtg tttatagaaa taaataaata tgtacataat
    16021 acataattat ttttaatcct aaaatacaag aatggagaga tggctatgaa gtggagagat
    16081 tatgctgatg atgtaaattt atttgaggat tttgataaaa ctatcaagcc tctaactgac
    16141 gaacaaagaa gaaaaaatat aaacacttta attgcatatt tttcaaaaga agttccttct
    16201 aaaatataca atttatcaaa tgatgaaatt aagcctagag atatacttag aggacttttg
    16261 aatgtatatc caccaaaaga aattgctcca gagatactta atatgttaca taatttattg
    16321 ttgattgaat gtgaagaaag agagttagta gatgtaaatg atatagaaga agttgaggaa
    16381 gggattgcca tatggagagg taatataacg aatttaagag cagatgcaat agtgaatgct
    16441 gcaaataaca agttattagg gtgtttacaa ccattacatc tatgtgtaga taatgagata
    16501 cattcatgtg caggacctag acttagagaa gattgtaaca aaataataaa aaaacaagga
    16561 catttagaat atactgggga tgctaagata actagaggtt attgtttacc tgcaaaattt
    16621 gtagtacata ctgttggacc tattgtgtct ggtggtcagc caagtaaaga gcaagaaaag
    16681 caattacttc attgttataa atcatgttta aatacaataa aagaaattga tgaaataaaa
    16741 aatattgttt tttgtggaat ttctacaggt gtatttggtt atccaaaaaa agaggcagct
    16801 aatcttgctg taagtagggt tagattatgg ctaaaagaaa accctgaaaa aaatttaaaa
    16861 gttgtattta atgtttttac tgaagaggaa gaagagaaat atagaagaat atttaaataa
    16921 tattatataa caaatcctaa aaatacttat tatataatcc tataatacaa attcattgta
    16981 taagataata atttgcaagt agtaaaaatt aataaaatat aatttgtatt tttaataaat
    17041 aagtag
//
LOCUS       DBGJFK010000084        16507 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.084, whole genome shotgun sequence.
ACCESSION   DBGJFK010000084 DBGJFK010000000
VERSION     DBGJFK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16507
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.084"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..540
                     /locus_tag="ACOIAP_003117"
     CDS             <1..540
                     /locus_tag="ACOIAP_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HGZ2639994.1"
                     /translation="DVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGV
                     EMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEG
                     GRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRF
                     SIREGGRTVASGVVATIIE"
     gene            790..939
                     /gene="rpmG"
                     /locus_tag="ACOIAP_003118"
     CDS             790..939
                     /gene="rpmG"
                     /locus_tag="ACOIAP_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGZ2639995.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            965..1186
                     /gene="secE"
                     /locus_tag="ACOIAP_003119"
     CDS             965..1186
                     /gene="secE"
                     /locus_tag="ACOIAP_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGZ2639996.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTG
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            1206..1748
                     /gene="nusG"
                     /locus_tag="ACOIAP_003120"
     CDS             1206..1748
                     /gene="nusG"
                     /locus_tag="ACOIAP_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGZ2639997.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1796..2221
                     /gene="rplK"
                     /locus_tag="ACOIAP_003121"
     CDS             1796..2221
                     /gene="rplK"
                     /locus_tag="ACOIAP_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGZ2639998.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            2292..2990
                     /gene="rplA"
                     /locus_tag="ACOIAP_003122"
     CDS             2292..2990
                     /gene="rplA"
                     /locus_tag="ACOIAP_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGZ2639999.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    3042..3170
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            3213..3719
                     /gene="rplJ"
                     /locus_tag="ACOIAP_003123"
     CDS             3213..3719
                     /gene="rplJ"
                     /locus_tag="ACOIAP_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGZ2640000.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3777..4142
                     /gene="rplL"
                     /locus_tag="ACOIAP_003124"
     CDS             3777..4142
                     /gene="rplL"
                     /locus_tag="ACOIAP_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGZ2640001.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4511..5299
                     /locus_tag="ACOIAP_003125"
     CDS             4511..5299
                     /locus_tag="ACOIAP_003125"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGZ2640002.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEDKIDILVNNFGSTNPSLDRDL
                     LTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPAFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5772..9488
                     /locus_tag="ACOIAP_003126"
     CDS             5772..9488
                     /locus_tag="ACOIAP_003126"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0032549 - ribonucleoside binding [Evidence
                     IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGZ2640003.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIMKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9530..13015
                     /gene="rpoC"
                     /locus_tag="ACOIAP_003127"
     CDS             9530..13015
                     /gene="rpoC"
                     /locus_tag="ACOIAP_003127"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGZ2640004.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNEKIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKSLGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREVDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            13305..13727
                     /gene="rpsL"
                     /locus_tag="ACOIAP_003128"
     CDS             13305..13727
                     /gene="rpsL"
                     /locus_tag="ACOIAP_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGZ2640005.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13850..14320
                     /gene="rpsG"
                     /locus_tag="ACOIAP_003129"
     CDS             13850..14320
                     /gene="rpsG"
                     /locus_tag="ACOIAP_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGZ2640006.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14369..16435
                     /gene="fusA"
                     /locus_tag="ACOIAP_003130"
     CDS             14369..16435
                     /gene="fusA"
                     /locus_tag="ACOIAP_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGZ2640007.1"
                     /translation="MARKFPLEKTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFINKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6486 a         2067 c         3371 g         4583 t
ORIGIN      
        1 gacgtattct caatcacagg aagaggaaca gttgcaacag gaagagtgga aagaggagta
       61 ctaaaagtac aagacgaagt agaattagta ggattaacag aagcaccaag aaaagtagta
      121 gtaacaggag tagagatgtt cagaaaatta ttagaccaag cacaagcagg ggataatata
      181 ggagcattat taagaggagt acaaagaaac gagatagaaa gaggacaagt actagcaaaa
      241 actggatcag taaaggcaca cacaaagttt acagcagaag tatatgtact taaaaaagaa
      301 gaaggtggaa gacatacacc attctttgat ggatatagac cacaatttta cttcagaaca
      361 acagacgtaa caggagcttg taagttacca gaaggaatag agatggtaat gcctggagat
      421 aacgtaacaa tggaagtaga cttaataaac tcaatagttg tagaagaggg attaagattc
      481 tcaataagag aaggtggaag aacagtagct tcaggagttg ttgctacaat aatagagtaa
      541 ttctttacta aactgatgga ttaaaaggaa taacaaaaag aggggttatg ctcctctttt
      601 tttaacatag aaatacaaaa acattgacac agcataggat tttgtgataa cttatacaag
      661 gtaatgatta taggaagtta ataatatctt gaatactgta gatttttaat aaatacatat
      721 tttaaagata ttatattcac atatattaac aatatatatt attgtattac aaagttggag
      781 gtgtatcaga tgagagttaa agtaacttta gcatgtacag agtgtaagca aagaaactac
      841 aacactacta agaataagaa aaataatcca gacagaatag aattacaaaa atattgtaga
      901 ttctgtaaaa agcatacaac tcataaagaa acaaaatagt tttttataag gatgtgagta
      961 tggaatggct gcccaaaaaa atgacggtgc aaaaactaaa aaaaggttta gtttgtttgg
     1021 atacttaaaa gaaactaaac aagaattaaa aagagttaca tggccgacaa aaaaggaact
     1081 gtttaaaaac acaggtatag ttttaactgt agttatttca tgcactatat tagtatgggg
     1141 tatagacact atattatctg gtgcactagc gttattacta aaatagacga aaagaggtaa
     1201 gttaaatgtc agaattacaa gaagcaagtt ggtatgtagt tcatacttat tcgggacatg
     1261 aaaataaagt taaagctaca attgagaaag cagttaaaac aagaggtatg gaagactgca
     1321 taagacaagt agttgttcca acagaagaag tagtggaaac tactaaaact ggaaaagaaa
     1381 aaactagaca acgtaaagtt tatccaagct atgttttggt taaaatgata ataactgatg
     1441 aatcttggta tgtagtaaga aatactaagg gagttacagg tttcgttgga cctggttcaa
     1501 aaccagtgcc attaagtgaa gacgaagtca aagctatggg gatagataca acagacccta
     1561 aagtagtaaa tagcgatatt gattttgaaa taggagatac agtaaaagta tctcaaggac
     1621 catttagtgg acaaataggt aacatagaag aaattgactt agagaataga gaagtcaaag
     1681 tatgcataaa tgcatttggt aaaaggactc tatttgtaat agagcttgaa ggtatagaaa
     1741 aaatctaata ctatatttat aatattatag aaaaatctga ggaggtgcgc tcaaaatggc
     1801 taaaaaagtt ataggtcaaa taaaattaca aatacctgca ggaaaggcta ctccagcgcc
     1861 accagttgga ccagcattag gacaacatgg tgttaatata atgggattca caaaagaatt
     1921 taatgcaaaa actgcagatc aagctggaat gataatacca gttgttataa ctgtatatca
     1981 agatagatca ttcagtttta taacaaaaac tccaccagct gcagttttaa ttaaaaaagc
     2041 attaaactta aaatcaggtt ctggagaacc aaacaagaaa aaagttgcta aaatgacttc
     2101 agctcaagta agagaaatag ctgaattaaa gatgcctgac ttaaatgctg catcagtaga
     2161 agctgctatg agtatgatag ctggtactgc tagaagcatg ggtgttgtaa tcgaagacta
     2221 attaaaagat acactttttt ttataaagtg ggaggcgaga agccgaaatt aaccacaagg
     2281 aggaaaataa aatggctaaa aaaggtaaaa gatatgcagg tgcattacaa aaagtagata
     2341 gaactaaatt ttatgatgca tcagaagcat taacattagt ttcagatata gctggagcta
     2401 aatttgatga gacagtagaa gcacacatta aattaggtgt tgactcaaga catgctgacc
     2461 aacaagtaag aggtgcagtt gtattacctc atggaactgg taaaactaaa agagttttag
     2521 tttttgctaa aggtgaaaaa gctaaagaag ctgaacaagc tggtgctgac tttgtaggag
     2581 ctgaagaatt agttcaaaaa atacaaggtg aaaactggtt tgactttgat atagtagttg
     2641 ctactccaga catgatgggt gtagtaggta gattaggtag agtattagga cctaaaggtt
     2701 taatgccaaa ccctaaatca ggaacagtta catttgatgt agctaaagct atagatgaaa
     2761 taaaagctgg taaagttgaa tacagattag acaaaactaa cataatacac gttccagtag
     2821 gaaaagtatc atttggtgga gaaaaattaa ctgaaaactt tactgcatta atggatgcta
     2881 taataaaagc taaaccagct gctgctaaag ggcaatattt aagaagtata acagtagctt
     2941 cttcaatggg acctggagtt aaaataaacc cagcaagaac agctgaataa taaaactgtt
     3001 gacacaggtt gacaaaaatg ttatcatatc acttgtcaat gtaaaaaaga atagatttgc
     3061 cgtagatagt gggtgcgaaa gcttaatatc ccgccgaggt tttagataaa ttgagattac
     3121 taaagctttt gatgtctact tttggcaaca aaagcttttt ataatgttgc ggtaaatact
     3181 aagcctattt ggtgaaggag gtgcacatct atatgagaaa agctatagaa attaaatcag
     3241 aagttgtttc tgagatagtt gaaaagttac aaaaatcttc tgctgctgtt gttgtagatt
     3301 acaaaggatt aacagttgaa gaagtaactg agttaagaaa acaaatgaga gaagctggtg
     3361 tagattacaa agtatataaa aatactttag ttagaagagc agctaaagaa gttggtatag
     3421 agcaatttaa tgatgaatta ttagttggaa ctaatgccat agcatttgga tatgatgatc
     3481 cagttgctcc agctagaata ttaaaaggat tcatggattc tcatccaaaa atgaaattaa
     3541 agatgggtat tgtggaaggt gcattttatg atgagtctaa gattgttgaa atggctaaca
     3601 taccatcaag agaagttctt atcgctaaat tacttggtag cttaaaagct ccagtatcaa
     3661 acttcgcata cttaatagat gcaatagcga aaaaggcaga aggtcaagaa gaagcttaat
     3721 tgcttaacta aaaaattata aatattaatt tgaaataaaa ttcggaggtg ctaaaaatga
     3781 caatagaaca aatattagaa gctatagaaa atatgaaagt tttagaatta aatgaattag
     3841 ttaaagctgc tgaagaaaaa ttcggtgtat cagcttcagc tccagtaatg gtagctggtg
     3901 cagctgctgg tggaccagct gctgaagaaa aaactgagtt tgatgtagta ttaactgacg
     3961 ttggttcttc aaaagttgga gttataaaag cagttagaga aataacagga ttaggattaa
     4021 aagaagctaa agaagtagtt gacaatgctc ctaagacagt taaagaagga gcttctaaag
     4081 aagaagctga tcaaataaaa gaaaaattag aagctgctgg agctaaagta gaagttaagt
     4141 agtttcttta aaaagatacc cattgggtat cttttttatt tataaaaaat tataaaggaa
     4201 gtatttttat aaaataaaaa aaaattatat aatagtacta aattaagggt atcatatatg
     4261 atgtaatggt attttaattt aatattatta taaaattaaa atataaacaa ttgttgtaat
     4321 gtatatatat aaagtatata attaaattga aatgtaaaaa attacatatt attttaaaaa
     4381 aatacacgat agttttataa ataaaatgta ataaataatt aattaacaaa tatgaatttt
     4441 aaaataagtt aaacatttag aaaaatcgaa atttgcagga tttaaagaca tatttaagga
     4501 ggagttaata atggaaaaat tacaaggaaa aattgcagta gttactgcgg caacaaaagg
     4561 tattggatta gcatcagcag agatattagc aaaaaatgga gcaactgtgt atttagcagc
     4621 tcgttcagaa gaattagcta atgaagttat aaataaaata agtgcagaag gtggctgtgc
     4681 taaatttgtc tactttaatg cacgtgaaga agaaactttt acctcaatga tagaagaggt
     4741 agttaaaaaa gaagacaaga tagatatact tgtaaataac tttggttcaa caaacccttc
     4801 tcttgataga gaccttttga ctggtgatac agataatttt tttgatacag taaatactaa
     4861 tttaaagagt gtatatttac catgtaaagc agcaattcct cacatgataa agaacgggaa
     4921 gggaagcata gtaaatatat ccagtatagg ctcagttttg cctgatttat ctagaatagc
     4981 ttactgtgta tcaaaagcag caatcaattc attaactcaa aatatagcta cacaatatgc
     5041 caaagataat gttagatgta atgctgtact tccaggtctt attgcaacta aggctgcatt
     5101 agataatatg tctccagcat tcataaaaga atttttaaaa catgttcctt taaatcgtat
     5161 aggagaacca gatgatatag caaaagcagt tttattctat gctagtgatg attcatcatt
     5221 tataacagga gatttgcttg aggttgcagg tggatttggt ttacctactc cacaatttgc
     5281 agataatata ttaggataat taaattacta atatgtaatg aaggctttat gtattagtta
     5341 tagtatataa ggatattttt ataaagacca tagatataat ttatattgga aaagtttgcg
     5401 gttcaaaatt ccaagttaaa tttatttatg gtttttattt tgcatattct aataaattgt
     5461 atatatttgt ataaatgtaa ttatttacaa tcattttaat atagaattat aattaaatag
     5521 gggggatggt atttgtataa aattttatat agaaaattag tcctataaat gaaaaatatg
     5581 gattttatat tgggaaattg tacataatac ataatatatg cttaaaataa tttacaaaaa
     5641 atcaaaaata atgcatagtt tacatataag ataaaaaata tattgaaaaa tacttgacat
     5701 tatgctaaaa ttattagatg cgttagaatg aactattgtt ttatttttaa ttattgagag
     5761 gtgaaaagtg aatgccacat cctgtcacga taggtaaaag aactagaatg agcttttcta
     5821 aaattaagga aatagctgat gtgccaaatc ttatagaaat ccaagtagat tcctatgagt
     5881 ggtttttaaa agaaggttta aaagaagtgt ttgatgatat ttcaccaata gaagattata
     5941 ctggtaatct tatattggaa tttgtcgact attctctaga tgataaacca aagtacgata
     6001 tagaagagtg taaagagaga gatgctacat attgtgcacc tctaaaggtt aaggtaagac
     6061 ttataaataa agaaacaggt gagataaaag aacaagaagt atttatgggt gacttccctt
     6121 taatgacaga aagaggaact ttcgttataa atggagcaga aagagttata gtaagtcaat
     6181 tagttagatc tcctggtgtt tactatgcgg aagaaagaga taaaacaggt aagagattga
     6241 tttcatctac tgtaattcct aatagaggag catggttaga atatgaaaca gattctaatg
     6301 atgtaatatc tgtaagagtt gatagaacaa gaaaacaacc agttacagtt ttacttagag
     6361 ctttaggaat aggaacggat gcagagataa ttgacctttt aggagaagat gagagattat
     6421 ctgctacatt agaaaaagat aatactaaga cagtagaaga aggtcttgta gagatataca
     6481 aaaaattaag accaggtgaa cctcctactg tagaaagtgc atcatcttta ctaaatgctt
     6541 tattctttga cccaaaaaga tatgacctag caaaagttgg tagatataaa ttcaataaga
     6601 aacttgcttt atgttataga ataatgaata aaatttcagc agaagacata ataaatccag
     6661 aaactggtga agtatttgta aaagctggag aaaaaataag ctatgatttg gctaaagcca
     6721 tacaaaatgc aggtataaat gtagtaaatc tactaatgga tgatgataag aaagttagag
     6781 ttataggaaa taattttgtg gatattaagt ctcacattga ttttgacata gatgatttaa
     6841 acataaaaga aaaagtacat tatccaactt taaaagaaat attagatgga tatagtgatg
     6901 aagaagaaat aaaagaggct ataaaatcaa gaattaaaga acttatacca aaacatatat
     6961 tattagacga tataatagct tcaataagtt atgagttcaa tatattctac aatataggaa
     7021 atattgatga tatagatcac ctaggaaaca gaagaataag atctgtaggt gaattgttac
     7081 aaaatcaagt tagaattggt ctttcaagaa tggaaagagt tataaaagaa agaatgacag
     7141 ttcaagatat ggaagctata acgcctcaag cgttagttaa cataagacca gtttcagctg
     7201 caataaaaga attttttggt agttctcagt tatctcagtt catggatcaa acaaatcctc
     7261 tatctgagtt aacacataag agaagactat cagcccttgg acctgggggt ctttcaagag
     7321 aaagagctgg atttgaagtg cgtgacgttc accattcaca ctatggtaga atgtgtccaa
     7381 tagagactcc agaaggacca aatatcggtc ttataaactc tctaggaact tatgcaaaga
     7441 taaatgaatt tggatttata gaatcaccat atagaaaatt tgataaagaa acatcaacag
     7501 ttactgatga aatacattat ttaactgctg acgaagaaga tttattcgta agagctcagg
     7561 caaatgagcc attaacagaa gatggtaaat tcgtaaacca tagagttgtt tgtagaactg
     7621 taaatggtgc tgttgaaatg gttcctgaaa gtagagtaga ttacatggat atatctccta
     7681 agcaagttgt atcagttgcc actgctatga tacctttctt agaaaatgat gatgctaacc
     7741 gtgcccttat gggagcaaac atgcaacgtc aggcagtacc tctagttaga agagaagcac
     7801 caattatagg aactggtata gaatacagag cagcaaaaga ttctggagca gttgttgttg
     7861 ctagaaactc tggtatagca gaaagagtaa cagcagatga aataattata aaaagagaag
     7921 atggaaatag agatagatat aatctactta agtttaaacg ttcaaactca ggtacttgta
     7981 taaatcaaac acctataata aataagggtg accagataat gaagggtgat gttatagcag
     8041 atggtccagc aacagactta ggagaagttg cacttggaag aaactgcctt atagcattca
     8101 tgacttggga aggttataac tacgaggatg ctatattaat aaatgaaaga ttagttaaag
     8161 aagacagatt atcaacaatt catatagaag aatatgaatg tgaagctaga gatacaaaac
     8221 taggaccaga ggaaataact agagatatac ctaatgttgg agatagtgca attaagaact
     8281 tagatgacag aggtataata agaataggtg cagaagtaga ttcaggtgat atactagttg
     8341 gtaaagtaac tccaaaagga gagactgaac ttactgctga ggaaagatta cttcgtgcaa
     8401 tatttggaga aaaggctaga gaagttagag atacttcact taaagtacct catggtgaat
     8461 ctggtataat agtcgatgta aaagtgttta ctagagaaaa tggagatgat ttatctccag
     8521 gagtaaatga attagtaaga tgttatatag ctaaaaagag aaaaataaaa gttggagata
     8581 aaatggctgg tcgtcatggt aataaagggg ttatctcaag agtgttacct gaagaagata
     8641 tgccattcat ggaaaatgga acaccactag atataatact taacccacaa ggtataccat
     8701 cacgtatgaa cattggtcag gttctagaag tccatttagg acttgctgct aaaacattag
     8761 gatggtatgt agcaacatca gtattcgatg gtgctaatga gtatgatata atggatgctc
     8821 ttgaagaagc tgggtatcct agagatggta aattaacttt atatgatggt agaacaggtg
     8881 agtcttttga caatagaata actgttggat atatgtatta cttgaaacta catcacttgg
     8941 tagatgaaaa actacatgca agaagtactg gaccatactc attagttact caacagccac
     9001 taggcggtaa agcacaattt ggtggacaaa gatttggaga gatggaggtt tgggctctag
     9061 aagcatatgg ggctgctcac atacttcaag aaatacttac tgttaagtct gatgacgttg
     9121 taggtcgtgt tagaacatat gaagctatag ttaaaggtga aaatatacct gaaccaggaa
     9181 tcccagaatc atttaaggtt cttataaaag aacttcaaag tttatgctta gatgtaaaag
     9241 tattgacaga tgaagaccaa gaaatagaag taagagaatc tgtggatgaa gatgatacaa
     9301 taggtgaatt tgagctagat gttgtaaatc atatgggaga agttgaagaa agtaatataa
     9361 tagaagaaat tgaagatgat tttgcagaaa acgcagaaga tgaggatata gagaatttag
     9421 aagaattcac tgaagatgat ttatttgaag aagaaataga ttttgatagt gatgactttg
     9481 atatgtaaat ttaattaatg taaatctcaa atagaaggga gagaactcct tgtttgaatt
     9541 aaacaatttc gagtcgataa aaatagcatt ggcttctcca gaaaaaataa gacaatggtc
     9601 taggggagaa gttaaaaagc cagaaactat aaattaccgt actttaaaac cagaaaaaga
     9661 tggtcttttc tgtgaaagaa tatttggacc acaaaaagac tgggagtgcc actgtggtaa
     9721 atatagaaga gttagatata aaggtgtagt ttgtgataga tgtggagtag aagtaactaa
     9781 atcaaaagta agaagagaga gaatgggaca tatagagcta gccgctccta tgtctcacat
     9841 ctggtacttc aaaggtatac caagtagaat gggactttta cttgacatgt caccaagatc
     9901 attggaaaaa atattatact ttgcatcata tgtagtagtt gatccaggag aaactggatt
     9961 aaacgaaaaa caattgctta cagaaaaaga atacagaact gctcttgaaa agtatggata
    10021 tacttttact gtaggaatgg gtgcagaagc tgtaaagacg ttactacaaa atatagattt
    10081 agaacaacaa agtaaagacc taagagcgga gttaaaagat agtacagggc aaaagaaagt
    10141 tagaacaata agaagattag aagttgtaga agcatttaaa aagtctggaa ataaaccaga
    10201 atggatgatt ttagatgcga taccagtaat accaccagat ttaagaccaa tggtacaact
    10261 tgatggtgga agatttgcaa cttcagacct aaatgattta tatagaagag ttataaatag
    10321 aaacaataga cttaaaagat tattagagct tggagctcca gatataattg taagaaatga
    10381 aaaaagaatg cttcaagaag ctgttgatgc actaatagat aatggtagaa gaggtagacc
    10441 tgtaacagga cctggaaata gaccacttaa atctttatca gatatgttaa aaggtaaaca
    10501 aggtcgtttc cgtcaaaact tacttggtaa gcgtgttgac tattcaggac gttctgttat
    10561 agttgttgga ccagagctta agttctatca atgtggactt ccaaagaaga tggcattaga
    10621 gctattcaag ccatttgtta tggataaatt agttaaagaa ggatatgcac ataatataaa
    10681 aagtgccaaa tctatagtag aaaaagttaa gccagaagtt tgggatgttt tagaagatgt
    10741 tataaaaagc catccagttc ttcttaaccg tgcgccgact ctgcatagat taggtataca
    10801 agcatttgaa cctatcttag ttgaaggtaa agctataaag ctacatcctc ttgtatgtac
    10861 agcttacaac gcagactttg atggtgacca aatggcagtc catgtacctt tatcagtaga
    10921 agcgcaagca gaagcaagat tcttaatgct ttctgtaaat aatatacttg ctcctaaaga
    10981 tggttcacct ataactactc catctcagga tatggtttta ggctgttatt atctaacaat
    11041 agaagcacaa gacggagcta agggaacagg tatggtattt aaagacttta atgaactatt
    11101 acttgcttat tacaataagt cagttcatct acatgcatta gtaaaactga aggtaacact
    11161 tgaagatgga agaagttcat tagttgaaag tactgttgga agatttatat ttaatgaaaa
    11221 aatacctcaa gacttaggtt ttgtagatag aaaagaaaac ccatttgctc ttgaagttga
    11281 tttcttagca gataaaaagt ctcttggtaa aataatagat aaatgcttta gaaaacatgg
    11341 taatacagag acagctgaat tgctagatta tataaaatct ttaggattta aatactctac
    11401 attaggtggt ataacagttg cagtagatga tatgagtgtt ccagaagaaa agaaagtatt
    11461 tatagctgag gcagaagcta aagttgataa atatgaaaaa gcatacagaa gaggtctaat
    11521 atctgatgaa gaaagatatg aaaaagttat agagacatgg acagaaacaa ctgataaagt
    11581 tactgacgct cttatgggtg gactagatag actaaataat atatatataa tggcacattc
    11641 aggagccaga ggttctaaaa accaaattag acagctagca ggtatgcgtg gtcttatggc
    11701 gaatgcatct ggtaaaacag ttgagatacc agttaaatct aatttccgtg aaggtttatc
    11761 agtattagaa tactttacat cttcacatgg tgccagaaaa ggtcttgcag atacagctat
    11821 acgtacagct gaatctggat acttaacaag aagacttgtt gatgtaagtc aagatgttat
    11881 tgtaagagaa gtagattgtg gaacagaaga tactacagaa atttatgcta taaaagaagg
    11941 aaatgaagtt atagaagaaa tatatgatag aattgtagga agatatacta tagaccctat
    12001 attaaatccg gaaactggag aagttatagt tgaggctgat tcaatgatac aagaagatga
    12061 agcagaaact atagtagctt taggcattga aaaaattagg ataagaacag ttcttaactg
    12121 taaaactaat catggagttt gttctaagtg ttatggtaga aacttggcta caggaaaaga
    12181 agttaatata ggtgaagcag ttggtataat agcagctcaa tctatcggtg aaccgggtac
    12241 tcagcttaca atgcgtacat tccatactgg aggagttgca ggagctgaca taactcaagg
    12301 tcttccaagg gttgaagaat tatttgaagc tagaaaacca aaaggattag ctgtaataac
    12361 tgaagtatct ggtagagttg aaattgatga aacaggaaag agaaaagaag taaatgtaat
    12421 accagaagaa ggcgagactc aaacatatgt aattccatat ggttctagat taaaagttaa
    12481 gcaaggtcaa atgctagagg ctggagaccc tctaacacaa ggatttataa atcctcatga
    12541 tatcgtaaga gtaaatggtg ttaagggagt tcaagaatat atagttaaag aagttcaaag
    12601 agtgtataga cttcaagggg ttgatgttaa tgataagcat atagaagtta tagtaagaca
    12661 aatgctatct aaagtaaaag ttgaagaccc aggagataca gatttattgc caggtggata
    12721 tgaagatgta ttaacattca atgaatgtaa taaagatgct atagataaag gtctaagacc
    12781 agcagttgct aaaagagttt tacttggtat aactaaagca tctcttgcaa ctgattcatt
    12841 cttatcagca gcttctttcc aagaaacaac aagagtatta acagaggcag caataaaagg
    12901 taaagaagac cacttaatag gacttaaaga aaatgttata ttaggtaagt taataccagc
    12961 aggaacagga atgaagaaat atagaaatat agctgttgaa aaaattgaag attaatagca
    13021 tatagagtaa agaaatcttg acaaccatta tttgtggtgt taaaatagta aagtgtgttg
    13081 tttaaaagta cactaagggc ttgaacaagc tcttagtgac ttttagatgg caataaataa
    13141 gaactaaaaa gcatcaagct agaaaagtgc taatatcaca tatttatgtg ttatagacat
    13201 taaattgtaa gtaacgaatg ttacaatcag tcagtatgaa taattcatat tgatgtagtt
    13261 ggcggtcact gataagatcg aaaatttgga aggaggtgca gatgatgcca acaattaacc
    13321 aattagttcg taaaagtaga aaagcgctag agaagaaatc tactgctcca gcattacaaa
    13381 aaggttacaa ctctttaaat aagaaagtaa ctgacgctag tgccccacaa aaaagagggg
    13441 tttgtacttc agtaaaaaca gttactccta agaagcctaa ctcagcttta agaaaagttg
    13501 ccagagttag attaactaat ggtatagaag tttctgctta tataccagga gaaggacaca
    13561 acttacaaga gcatagtgtt gttcttataa gaggaggaag agtaaaagac cttccagggg
    13621 ttagatacca tatactaaga ggtactctag atacagcagg tgttgataag agaagacaat
    13681 caagatctaa atacggtgcg aagagaccta aagaagctaa aaaataaaac aattaatgat
    13741 tgattatagt tcggtgcttt aaatatatat atatttacgg catcacggca ttaaatgatt
    13801 tatgtcgagt acctatgatt taagttaaat aattaaggag ggaagcgaaa tgccaagaaa
    13861 aggtaatatt ccaaaaagag aagttttacc agatcctatg tatgggagta aggtagttac
    13921 taaattaata aataatctaa tggtagacgg aaaaaaagga aagtctcaaa gaatagttta
    13981 tgatgctttc gcaattgttg ctgaaaagac aggagaagaa gctttagaag tatttaataa
    14041 agcaatggat aatataatgc ctgttttaga agtaaaagca agaagagttg gtggagcaaa
    14101 ctaccaagtg ccaatcgaag ttagacctga aagaagacaa acattaggtt taagatggct
    14161 agtaaaatat actagagctc gtggtgaaaa aggaatggtt gaaaagctag ctaaagagat
    14221 aatggatgca gctaacaaca ctggagcttc agttaagaaa aaagaagata ctcataaaat
    14281 ggcagaagct aataaagcat ttgctcatta cagatggtag gatatataga tatcttataa
    14341 attcaaggat atcataagga ggataaccat ggctagaaag tttcctttgg aaaaaactag
    14401 gaatatagga atcatggctc atatagatgc aggaaagact actactacag aaagaatcct
    14461 gttttatact gggcaaactc ataaaatagg agaaactcat gaaggagctt ctcaaatgga
    14521 ctggatggag caagaaaagg aaagaggtat aacaataact tctgccgcta ctactgcttc
    14581 atggaaagac catagaataa acataataga tactcctgga cacgtggact tcacagttga
    14641 ggttgaaaga tctctaagag ttcttgatgg ttcagttgct gtattctgtg caaaaggtgg
    14701 ggttgagcct caatctgaaa atgtatggag acaagctgaa acttatggag tacctagaat
    14761 agcttttata aacaaaatgg atatattagg tgcagatttc tacaatgttg taagcatgat
    14821 gaaatctaga ttaaattcta atgcagttcc tatgcaatta ccaataggta aagaagattc
    14881 atttataggt ataatagact tattaaaaat ggatgctgtt atatacaaag acgacttagg
    14941 ggttgaaatg gaagaaacag acataccaga agatatgaaa gaattagctg ctgagtggag
    15001 agaaaaatta gttgagtcag tagctgaaac tgatgaagaa ttaatgatga aataccttga
    15061 aggtgaagaa cttactatag atgaattaaa agttgctata agaaaagcta ctatagcttg
    15121 tgaaatgaac ccagttttct gtggtacagc ttatagaaac aaaggtgttc agttagtaat
    15181 agatgcagtt ttagattact taccagcacc aactgatata ccagctataa aaggtatatt
    15241 agcagatgga gaagaagctg aaagacattc ttctgatgaa gagccattct ctgcattagc
    15301 attcaaaata atgactgacc cattcgttgg aaaactagcg ttcttcagag tttattctgg
    15361 aacattagaa tctggttctt atgttttaaa tgcaactaag aataagagag aaagaattgg
    15421 tcgtatatta caaatgcatg ccaatacaag agaagaaata actaaagttt atgctggaga
    15481 tatagcagca gcggtaggat taaaagatac tactactgga gacacattat gtgaccctgc
    15541 taatccaata atacttgaat ctatggaatt ccctgagcca gttatatctg ttgctataga
    15601 gccaagctct aaagcagcac aagagaaaat gggtatagct cttcaaaaac tagctgaaga
    15661 agacccaact ttcacagtta agactgacca agaaacagga caaactataa tatctggtat
    15721 gggtgaatta cacttagaga taatagtaga tagattatta agagaattta aagtagaagc
    15781 taaagttggt gcaccacaag ttgcatatag agagactata actcaaccag ttgatgttga
    15841 atacaagtac tctaagcaat caggtggtag aggacaatac ggtcacgtta agattagagt
    15901 tgctcctcaa gagccaggtg aaggatacaa gttcacaaac aaaactgttg gtggatctgt
    15961 accaaaagaa tatgttggtc cagttgacat gggtatacaa ggagctatgc aatctggtat
    16021 agttgctgga tatccagttg tagacgttgc tgttgagtta tatgatggtt cttaccatga
    16081 ggttgactct tctgagatgg cgttcaagat ggctggttca atggcattca aagatgctat
    16141 gaagaaaggt aatgcagttc ttttagagcc ttacttcaaa gtagaagttg ttactccaga
    16201 agattacatg ggagatgtta tgggtgactt aaactcaaga agaggattaa tccaaggtat
    16261 ggaagctaga agtggtgcac aagttataaa tgcattcgtt ccactttcag aaatgtttgg
    16321 atactcaaca gacctaagat cttcaactca aggtcgtgca acttacacaa tgatattcga
    16381 tcactatgag caagttccag cttcagttgc taagaaaata gctgaaggaa aataatttaa
    16441 aaataattaa taatataaat ataaaaaata atcagctaga tgagatatat ctcatctagc
    16501 acaagat
//
LOCUS       DBGJFK010000085        16016 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.085, whole genome shotgun sequence.
ACCESSION   DBGJFK010000085 DBGJFK010000000
VERSION     DBGJFK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16016
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.085"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(95..733)
                     /locus_tag="ACOIAP_003131"
     CDS             complement(95..733)
                     /locus_tag="ACOIAP_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HGZ2640008.1"
                     /translation="MKGLILKDLLNLKGNVKFILLFIIMFGFMSSLGDGNINNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            complement(733..1587)
                     /locus_tag="ACOIAP_003132"
     CDS             complement(733..1587)
                     /locus_tag="ACOIAP_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640009.1"
                     /translation="MDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGKTTT
                     LKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIMSKI
                     YKNWSDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHNPKLLILDEATSSLD
                     PIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDELID
                     TMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIEEIM
                     LFYVRGDK"
     gene            complement(1593..1967)
                     /locus_tag="ACOIAP_003133"
     CDS             complement(1593..1967)
                     /locus_tag="ACOIAP_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2640010.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            2334..2738
                     /locus_tag="ACOIAP_003134"
     CDS             2334..2738
                     /locus_tag="ACOIAP_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HGZ2640011.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            2755..3351
                     /locus_tag="ACOIAP_003135"
     CDS             2755..3351
                     /locus_tag="ACOIAP_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640012.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIVKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            3388..5982
                     /gene="clpB"
                     /locus_tag="ACOIAP_003136"
     CDS             3388..5982
                     /gene="clpB"
                     /locus_tag="ACOIAP_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HGZ2640013.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSNRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETVIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(6159..7586)
                     /locus_tag="ACOIAP_003137"
     CDS             complement(6159..7586)
                     /locus_tag="ACOIAP_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGZ2640014.1"
                     /translation="MTNSFKKDENKKRMIVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLSSIEWVIASYSIIICSTLLFFGRLGDIIDKSRVFQSGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKENRGKALGILVTAVAIGNMVGPSIGG
                     FILSIFDWNFIFFINIPIGIIVIFLNTKFLPNSKKSSENMNKTGAILQFLGTTLFFSA
                     LISAQQAGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQNTMKLAPIQAGSFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLFMSFGFFLMSRLKESSALILFVIYISIISMGQAIFQPANNALIMSSCYRSKL
                     GIVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYIINNDKIFVFGMRNVYT
                     IITLICLIGAILIGFYLFKYDKNKQ"
     gene            7728..8624
                     /locus_tag="ACOIAP_003138"
     CDS             7728..8624
                     /locus_tag="ACOIAP_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGZ2640015.1"
                     /translation="MNDKNTYFDRKGKENFIDIFFKDDIKKGANFKRHWHEHLQVYYF
                     VDGIAYIECGLNNFKIVSGNIAIANSNELHYLESLSDNLKFYIIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSFILKCIKTILDEYHNKGIGYELSIKANIYQLIVL
                     LLRSHVDKIFSEDEFIERKYSLEKFEYIFDFIEEKYMDKITLKELASHVNLSVPHFCR
                     TFKKITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYDV
                     SPTKYRNEHREISNVILKEGIK"
     gene            9290..9430
                     /locus_tag="ACOIAP_003139"
     CDS             9290..9430
                     /locus_tag="ACOIAP_003139"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640016.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(9427..9798)
                     /locus_tag="ACOIAP_003140"
     CDS             complement(9427..9798)
                     /locus_tag="ACOIAP_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2640017.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTNISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            10342..10599
                     /locus_tag="ACOIAP_003141"
     CDS             10342..10599
                     /locus_tag="ACOIAP_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640018.1"
                     /translation="MIIIRSQDKTNLMYINQIKIDGSQVYAVFESNLDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITFNKVRYNVNKIFQMPVK"
     gene            complement(10709..11389)
                     /locus_tag="ACOIAP_003142"
     CDS             complement(10709..11389)
                     /locus_tag="ACOIAP_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGZ2640019.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVVIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSDLFRVDEINLIPFDSVGILTYILNVIMFMPLGFLL
                     PLIWKNFRNIINVLLTGLGFSLAIEFCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            11646..11945
                     /locus_tag="ACOIAP_003143"
     CDS             11646..11945
                     /locus_tag="ACOIAP_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640020.1"
                     /translation="MKWIKWYSFTCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKNNPVDGTTTIYYSYDNSTHIVRLSHPEDSSREINWDKVSNISFD"
     gene            12267..13922
                     /gene="ilvD"
                     /locus_tag="ACOIAP_003144"
     CDS             12267..13922
                     /gene="ilvD"
                     /locus_tag="ACOIAP_003144"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGZ2640021.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSTM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGNTIGENIRDCKIENEDVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFSKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIEKRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            14263..14889
                     /locus_tag="ACOIAP_003145"
     CDS             14263..14889
                     /locus_tag="ACOIAP_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2640022.1"
                     /translation="MNREEKSKNSKEKIIQSAFLLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLENLVADNTLTANEKIIKLVVHSANDYTRRK
                     MLHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPQELAGMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDECGIQKFKDLFK"
     gene            14918..15730
                     /locus_tag="ACOIAP_003146"
     CDS             14918..15730
                     /locus_tag="ACOIAP_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2640023.1"
                     /translation="MFYNAKSCQMMIDSNTVNYIEFGSGKKILIILPGLGDGLSPLHG
                     KIQAIAFAFRYKRFAKDYKVYMFSRKNQITEKYSTRDMAKDQADIIKKLGIMKAKVMG
                     VSQGGMIAQYLAIDYPDLVEKLVLTVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDV
                     ANKSYSEKYLKKYRLFIPLLGKVGKPKDFNRFIIQATSCIEHNSFSELNKITCPTLII
                     GGANDKIVGNKASFHLAEKIKRSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
BASE COUNT         6404 a         1791 c         2415 g         5406 t
ORIGIN      
        1 gtagaaatta ataattgaaa aataaaatac taccaaaata aaatcgatag tattttattt
       61 aaatacttaa atacagaaac atatatagta tattttatac ttctttttta ctatagattt
      121 ttgatgatat aaaatatgaa atcacaaata gtaaaatagc aacaaatgga agagaatata
      181 ctagtgtatt aagtataatt tctatagaaa taggtgaact aatattttct aaaatacttt
      241 taaaaactaa taaagctagt gttggaacta aaaagcataa aatcattaat aaacgagctc
      301 tttctgtacc aaatttataa ataagtggca aaataaggct accaaaacat actgaaattg
      361 ataagattag tgcattaata agtagtgttt catttaatat aagtgtattt ttaaaataac
      421 caatagttac actaacaata agtgaaacga gaacacctat gaagctaaat attaacatag
      481 ttaaatattt acttaataca atatcattgc gattaatagg cattgtaagt acataactat
      541 cccatttatt taaatcatca tatgaaaatg ttgaaacaat cattgtagta cataaaacta
      601 taataacacc tataaagtta ttaatatttc catctcctaa agaagacata aaaccaaaca
      661 taatgatgaa taaaagtata aactttacat ttcctttcaa attaagtaaa tcttttaaaa
      721 ttagaccttt cattatttat cacctctcac ataaaataac ataatttctt ctatagatgt
      781 attatcaaca atacagtttg gatgtcttga gataaatcta tgcttatctt taagaagtac
      841 ttcatatcca aattggcttt tacgataata tgaataatcc tctcttgaaa ggttatcaaa
      901 atcactaggt ttacatttta aaactcccat agtatcaatt aattcatcct tattttcact
      961 aaatacaatt tttcctttat gtataaatgt aatatagtct gctatcttat ctaaatcact
     1021 tgtaatatgt gaagataaga taatagagtg ttcttcatct tgtataaaat ctaaaaatat
     1081 atctagtatt tcttcacgaa cgatagggtc aagtgaacta gttgcctcat ctagtattaa
     1141 taattttggg ttatgagata aggctacagc aatactaagt ttcatcttat tcccctttga
     1201 aaactcctta attaatttat tgtctggtac tctcaatttt tttaagtagt ctttaaataa
     1261 tgtgtcactc caatttttat agattttact catgattttt gaaacatggt cagtgtttaa
     1321 attttcatga aagttgcttc cctcaaatac aaccccaatt tgctctttaa tttctttttc
     1381 atttttttta ctatcaagac caaagatttc tatatttcca ctatcataag atattaaatt
     1441 taaaattgct tttaatgtag ttgtttttcc tgcaccattt tcacctacaa atcccattac
     1501 actccctttt ggtactgaaa aagatatatc ttgtaggcta aaatctttat aagttttatt
     1561 taaatttttt atagttattg catccatact tatcattctc ctttatataa taaaaataaa
     1621 atatctttta attcgtcata tgtaatatca ctactttttg ctgtatcaac tgctttctgt
     1681 aggtattctt caattaaacg aaattgttct tctttgacaa aatccatgtt tttactagat
     1741 acaaaactgc ctttaccagt aactgtctca ataaatccgt ctcgttctaa atcgctatat
     1801 gctcgttttg tagtaattac acttattcta agttcttttg ccaatagtct catgcttgga
     1861 agagctgagc cttctggtaa ttctccactt ataatcatac ttttaatttg tgtagtaatc
     1921 tgttcatata ttggcttccc actcgaatta ctaataacta tattcaataa gacacctcct
     1981 taaattgtat atatagtata tacacattat ataaatatat atataatatg tcaactgatt
     2041 ttagaaaaaa ctaattgcca atattataca tttaataaat gtaatgtatt ttatgaaagg
     2101 ctaccatatt aaatagattt aaattttttt aaaaaattta taaatattat tcaaaaatcc
     2161 tgccaataaa ttggaaatac taaattaaaa aaataataaa gtttagctta taggtaaata
     2221 aaagtttatt tataagctaa actttttgtg ttttcagttt tgacatacat atttttttgt
     2281 aatatattta tattatcaat tagagataag gagagtgaga agagatattt aatttggata
     2341 agacattaaa aaaggattta aatcaggaat acacagagag taaaagttta gttatgaata
     2401 aaagtaagta tatgaatgtt tgttttaaga attatattaa agtagtagaa ggaatgtata
     2461 ctaagaggga tttaattcca ttaaaattaa taaactctat ggataaaaat aataagatta
     2521 gaaaaacatt atatgaatta tcttgtgaat ttgaatatcc aaaaacttct ttatcttcat
     2581 tgtttacgga gctgaaaaaa atggattttt tacaaagagt gaaaaatggt gagtatatga
     2641 taaatccaca tatagcatat aaaggtagta gagctgataa agaaagttta ttagcagaat
     2701 ataatcagat aaaaagacct aataaggtta gtaaataagg aagaaggttt ttatatgagt
     2761 ttaaaacttg atagaaatgt tctacagtgg tttgattatg tatttgagaa tgaaaaaact
     2821 agtttgagac actataattt taattgtaca ctaaaggaga ttagttctac cagtcttaat
     2881 aaagtagctt ttattttaga aaaaaataac tctaagtact ggaagcttta ttttgaaata
     2941 ccagctgaag ttactttaaa acttaagcaa aacattcatc ctttatttag ggaatatata
     3001 tacgaacaaa tatcactgta taacaataat caaatttaca attttgtaaa ttcaaacata
     3061 ttaaaagtgt ttaacaatat tgccatttat caatataata ttttagaaaa tctatacact
     3121 attgatttta aaaagagctt tatagataaa tgtcagtatt tattaatagg tgaaaaaaga
     3181 cttatagatg aagatttgta tttaatagta aaatcaaaag aagtatttga tttttttaat
     3241 tcagatggaa catttaattt aactttgagt ttcgatatac aaaaaaatga gaatttactt
     3301 gatagtcttt tagagcttag aaaatcaata attataaatg agagaattta atttatttgg
     3361 atataatatt aaaatggagg gatttatatg gacgtagaaa aaatgacttt aagagttcaa
     3421 aaaagtttaa atgaggctta taatgaagca gtaaaaaatc ataaccaaca agtagatgta
     3481 attcatcttt tctcagcact tattaatcaa gaagatggat taataccaaa tataatcgaa
     3541 aaaatgaata tatcaattga ttctttgaga aatactgtaa actttgaaat tgataagctt
     3601 ccaaaagtat atggagaagg agctgactca caaggagtat cagccactag aaaaataaat
     3661 gaggtgctta taaaggcaga gagcatttct aaagaattta aagactcata tataagtgta
     3721 gaacatgtta tgcttgcaat gatggaaaca gaatcaaaat cagctgttgg taaaatatta
     3781 aagcaatata atataaataa gaatgacttt ttaaacattt tatcacaagt gagaggtagt
     3841 caaagagtag aaacacaaga cccagaagga acatatgatg cacttgctag atatggaaca
     3901 aacttagtag atttagccaa gaaaaataaa ttagaccctg taattggaag agatgaagaa
     3961 ataagaagaa ttataagaat tttatcaaga agaactaaaa ataatcctgt gctaattggt
     4021 gagcctggtg taggtaaaac tgcaattgta gaaggtttag cagagagaat tgtaagagga
     4081 gatgtcccag aaggtttaaa agataaaatt gtattctcac ttgatatggg tgctttaatt
     4141 gctggtgcaa aatatagagg tgaatttgaa gaaagattaa aggcagtctt aaaagaagtt
     4201 caaagttctg atggaaaaat tatactattt atagatgaga ttcatactat agttggagct
     4261 ggtaaaacag aaggctcaat ggatgcaggc aatcttatta agcctatgct tgcaagaggt
     4321 gaattaaact gtattggtgc aactactttt gatgaatata gaaagtatat agaaaaagat
     4381 aaggctcttg agagacgttt tcaacctgta attgcagagg aacctactgt tgaagataca
     4441 atatctatac ttagaggttt aaaagaaaga tttgagatac accatggagt aagaatacat
     4501 gataatgcta ttgtagcggc agcaaaactt tctaatagat atatacaaga tagattttta
     4561 ccagataaag caattgactt aattgatgaa gctggagcta tgattcgtag cgaaatagat
     4621 tcattaccaa cagagttaga tgttgttaga agaaaattat ttacattgga aactgaaagg
     4681 gaagcattac ttaaagaaaa tgatgataaa agtaaatcaa gattggatga tattcaaaaa
     4741 gaaatagcag agttaaaatc taaaaatgat gaaatgacag caaaatatga aaaggaaaag
     4801 agtcaaatat tagatattaa aaacttaaag gctcaattag acgaagctaa aggtaaagct
     4861 gaaaaatatg agagagaata tgattttaat aaagcagcag aggttaaata tggtgaaata
     4921 cctaagttag aagaacaaat aaagcagtac gaagaaaata tgaacgatgg ttctgaaaat
     4981 tctcttttaa aagaagaagt tactgaagag gaaatatcta gcattgtatc aaagtggaca
     5041 ggtataccag taactaaact agttgaagga gaaagagaaa aattacttaa actagaagat
     5101 gaacttcata aaagagttat tggacaagat gaagcagtta cagcagtttc aaatgcagta
     5161 atacgtgcaa gagcgggatt aaaagatgaa agaaaaccaa ttggttcatt tattttctta
     5221 ggtcctacag gtgttggtaa aactgagctt gcaaaaactc ttgctagaaa tttatttgat
     5281 agtgaagata atataatcag aattgatatg tctgagtaca tggaaaaaca tgctgtatca
     5341 agactagttg ggcctcctcc agggtatgtg ggatatgaag aaggtggtca acttacagaa
     5401 gcagttagac gtgctcctta ttctgtaata ttatttgatg agatagaaaa agcacatgag
     5461 gatgtattta acatgttctt acagatatta gatgatggta ggcttactga taataagggt
     5521 aagacagtag actttaaaaa tactcttata ataatgactt ctaatatagg aagtaattat
     5581 ctattagaag caggagggaa tataacagag actactaata atttagtaat gaatgaaatg
     5641 aagcatagat ttaaacctga gtttttaaat agagtagatg atattataat gtttaagcct
     5701 ttagaccaag aaaatatcaa gaaaattata gatatattta tgaaagattt aaaaaataga
     5761 ttaaaagaaa aagatattac tattgaagtt acaaattcag caaaagatgt tatggtgaga
     5821 gagggatatg accctgtata cggagcaaga cctcttaaga gatatatagg aaatacatta
     5881 gaaactgtaa ttgcaaagaa acttattgct ggagatgtgt ataatggatg tactatagtt
     5941 atagatggaa aagatgaaaa tattgaagtt ttagttaaat aataagagaa tcagctgagc
     6001 atagtatatg aaatattttg ctcagctgat ttttatttat aaactatagg aaaagaaata
     6061 tttttaagcc aatgtgttca aattaaattt aactcaaagg gagtatttta gtaagtttct
     6121 tataatataa taatggtttg aatacaatta taaaaaaact attgtttatt tttatcatat
     6181 ttaaataaat aaaagccaat taatattgca cctattaggc aaataagtgt aataatagta
     6241 taaacatttc tcattccaaa tacaaatatt ttatcattat taattatata atcattgacc
     6301 ctatatccag ctttaatact cataaaatta tataaaagtg ttgtagaaat agtaatacct
     6361 ataacttgtc ctaaatttct tacaagggaa tttatgcttc ctacaattcc taacttactt
     6421 ctataacagc ttgacattat caaagcattg ttagcaggtt gaaatatagc ttgtcccatt
     6481 gatattatcg atatataaat tacaaataaa ataagggcag aactttcttt taatcttgac
     6541 attagaaaaa atccaaaact cataaagaga agaccaatta aaataatttt ttctgactta
     6601 attttatctg atatattccc aaatataggt gaaaaaatgg ctaaaatcaa aggtgataat
     6661 atcataaatg aacctgcttg aataggggca agtttcatag tattttgtaa ataaaatgga
     6721 attaaaatac tagatgatgc aatacaaatg aatgatgtaa gagcgcaaat taaattcaat
     6781 gaaaatttaa aatttctaaa aatttcaagg tcaagaagcg gttgaggatg ttttttttct
     6841 aatatcaaaa ataatataat aaaaataatt gataataata gtgcaattaa tatatatgga
     6901 tttagtaatc ctgcttgttg agcactaatt agagcactaa aaaataatgt tgttcctaaa
     6961 aattgaagta tagcaccagt cttattcata ttttctgaag attttttact attaggaaga
     7021 aattttgtat ttaaaaagat tacaataata ccgattggaa tatttataaa gaatataaaa
     7081 ttccaatcaa atattgacaa aataaatcct cctatagatg gtccaaccat atttccaata
     7141 gcaactgcag taactaaaat tcctagtgcc tttcctctgt tttcttttgg aaacagttct
     7201 gtgataatac catgattgtt tgccatgtag gcagaagcac ctatcccttg aataaagcga
     7261 caaactataa gtaaagttaa agaattactt aatccacata ataatgaagc tgatgtaaaa
     7321 agaatagtac ctgattgaaa tactctggat ttatcaataa tatccccaag tcttccaaaa
     7381 aataatagtg ttgaacaaat aataatcgag taacttgcta ttacccattc aatagatgat
     7441 agagatacat ttagtttgct tgcaagaact ggaagagcaa catttataat actagaatct
     7501 aatgttgcca taaaggtcat tgcaatgact acaaataaaa ctatcattct ttttttattt
     7561 tcatcttttt taaaagagtt tgtcattttt attacctcct tattataatg actggcatca
     7621 tgttaatgtt tacaataata gtcacatctt atataatatc ggtatgaaat aatgaataca
     7681 ataacgatat tgctcataat tagcactatt ttgataagag gtaaataatg aatgataaaa
     7741 acacatattt tgacaggaaa ggtaaagaaa actttataga tatttttttt aaggatgaca
     7801 ttaaaaaggg agcaaatttt aaaagacatt ggcatgagca tttacaagta tattattttg
     7861 ttgatggtat agcctatatt gaatgtggat tgaataattt taagatagta tctggaaata
     7921 ttgcaatagc aaatagtaat gaattgcatt atttagaaag tttatcagat aatttaaaat
     7981 tctatattat tcgaattgaa cccacattcc tttttagtaa tcaagttgat ttgttacaaa
     8041 ctaagtactt agcaccatta gctttaaatc atattgtatt taataattta attcaaaatg
     8101 attcttttat tttaaaatgt attaaaacta tacttgacga atatcacaat aaaggaattg
     8161 gatatgagct atctataaaa gctaatatct atcaattgat agtattatta ctaagaagtc
     8221 atgttgataa aatattttct gaagatgaat ttatagagag aaagtattct ttagaaaaat
     8281 ttgaatatat atttgatttt atagaagaaa aatatatgga taaaattaca ttaaaagaac
     8341 ttgctagtca tgtaaacttg agtgtgcctc atttttgtag aacatttaag aaaataacag
     8401 gtaagactac aatcgatttt ataaatggaa tcagacttga taaagctata tattatttaa
     8461 aggaaacaga tttaaatatg acagaaattg ctatgagatg cggctttgat agcataaatt
     8521 attttagtcg cttatttaaa aggaattatg atgtatctcc aactaagtat agaaatgaac
     8581 atagagaaat tagtaatgtt attttaaaag aaggtattaa ataattcata aatatacttt
     8641 atagaaaata tatattttta aatctttgag tttttcttaa taaacattaa taaagtatag
     8701 gatataaatg agtaagacta tttgtgtagt taaatttgaa aatgagtatg aaagaatgta
     8761 gtgtatatga aaagtgtact ttactatgaa actaaggttg gaaaaatagg aatagcagaa
     8821 aaaataatta tattacaaat ctgttttttt tgagacatct agcttagatt ctgaaagata
     8881 tttaattaaa gaaacaaaac tatcaaataa gtaagtaaac agctaaaaga gtatgctttt
     8941 tatagaaaac ttaaatacac tctaaagaat taaaagaaag tcaaatgagt ataaaaaaat
     9001 tatatgttta taaaaaattt tataataaaa atcatcctga aaaatatata aaaatagaaa
     9061 aaatatacaa gattctacaa taatagattt ttttgttatt attacgagtt ttttattgca
     9121 actgtagaat aaaagtatta ttatataatt aagataatta tctagggaaa ttttggataa
     9181 tcaaaatata ttttataaaa tcaaaataca attacataaa ctttattaaa aatttgttgg
     9241 gaatttctga ctaacattaa gaacgtaagt ttgttggggg atggtatatg tggaaaagtc
     9301 aaacactact gttacaaaaa aagaaaaaat tgaagatata ggaatgaaat tagaacattt
     9361 attgagtgaa gatattactt tttatgaatt attacttgag attttgtata aagaaaaaga
     9421 agagaattaa ttctcttctt taaggaatct ttttaaatag gcattatcaa tcattttttc
     9481 tatagcttct ctatcttctt tttcaagaga atatattttt tctaaaagtt tttttgtttt
     9541 ttcactcact gataagttct ctatgattaa tttatcttct ttgcttatgt ttgtgttatc
     9601 atttacgcct aataaataat ctgttgatgt ttctaatgct tttgctaatc tcactattat
     9661 ttcactttta ggttctctta aattattttc ataacgtgac aagctagcct cagttatacc
     9721 gactttagta gcaagttctt tttgatttat atctaattct tttcgtaaat ttgctattct
     9781 atctcctaaa ctttccatat gtacatcact ccttaccgaa attataagtt atttttataa
     9841 aaagtaaaat aaaattacca aaaatataaa aaaaaagaat taaaataaga aaatatattg
     9901 aaaattacca tttgtatatg tataataaga attatacaaa tggtaatttg atgagaggtg
     9961 gtattttgaa ataagaaacc gaattaatta gtaaacatat agaaagtttt gaatactgtt
    10021 acttgagata taaacaatat gcataaaaat ttttgaaagt aaaattacca aatgtataaa
    10081 ataaatcagt agcatagata gtttgatgct ttaatagatt atgtaattta gttataatag
    10141 ccaaaaatgc aatttaccaa taaaacaagg tattataaaa aaagtattct ttaagggaac
    10201 tttttattag atatgcaatt gatacaaata atcgtattaa aaaataaaat actaagttta
    10261 aaaatttaaa taatctagaa atcaattata aaatattatt tcttagaaac taaaattaat
    10321 taagtaaatg gaggaattga catgataata attagaagtc aagataaaac taatttaatg
    10381 tacataaacc aaattaaaat agatgggagt caagtttatg cagtatttga aagtaacctt
    10441 gatactgtaa aaataggaga ttatgaaaat aatacaagag ctatacaagt attggataat
    10501 atacaaaact tcattgaaaa tggaacaaaa tatgattata taacattcaa taaagtcaga
    10561 tacaatgtta ataaaatatt tcagatgcca gttaaataat gagtgtgcat tttagtttaa
    10621 taactaaagc ccgctttctt ttgaagtatg aaagagggct ttacacattt gtaaatattg
    10681 aagtacactt gttttgtcag taaattattt aataaggtat aatggaccaa ttaaacaata
    10741 aaaattctcc taaaacagca agtattaaat atataatagc ttcattttta taaagagagg
    10801 taattttttt gcttatatca tcatcaattg taatagcaat ttcatcttga ataatatttt
    10861 tatatataga tggaaaaata tcttttttct ttataagatt aaataaatta tttacaccta
    10921 cccatataaa atatcctaaa acagcaccta atgtgttcat cattaaatca tcaatatctg
    10981 tagctcttaa gttaaacaat tgacaaaatt caattgctaa tgaaaaacct aatccagtta
    11041 ataaaacatt gataatattt ctaaaatttt tccaaattaa aggtagtaaa aatcctaaag
    11101 gcataaacat aattacattt aaaatatatg ttaaaatgcc aactgagtca aaaggtatta
    11161 gatttatttc atcaactcta aaaaggtcac tataccttcc tatatcccat atgctaccaa
    11221 taccagcttt actaagtgct aggtatatat ataataaaaa aatatatacc catactaaat
    11281 gtatcactac atttttttca actttcaaat tttttctttt tataacaact atttggtata
    11341 ttaagcatgg taatataaca caaataaatg aataaaatgt ccatatcatt ttattttgtc
    11401 ccctttcaaa tttatgtttt tagttttata agtactatct ttatattaag cggtaagttt
    11461 taaaaatctt ttaataaaat cttaaaaatt tattaattta taaaatatat tatcaaaatt
    11521 aaaaagtata tataatcaag ttttctacaa ctatatatac atgtagaaaa attttatcgt
    11581 atgtataaat attataaata tatggaaata ataatagtat attttggtaa agtaggagga
    11641 attttatgaa atggattaaa tggtatagtt ttacatgtat atgtattttt atagtagtag
    11701 ctttttatat gtttatattt cctaataaaa tagaaactat tgatacttca tctgcatata
    11761 gttttgttga aaagaaagta ccaaatagtg ctgtgtatca aggatacaaa aataatccag
    11821 ttgatggtac tactacaatt tattacagct atgataattc aactcatata gttagattat
    11881 cacatccaga agactcttca agggagatta attgggataa agtttcaaac atcagctttg
    11941 attaatcttt aatatttata aaagtctata tgtataaggt aaatatatta ttaatcttat
    12001 tcatagttga gcactttcta ttatagaagt gctttttctg atttatagca taaaatatta
    12061 ctcaacaatt tgtaaaatat attagtttat aaaatatatt gaaaagataa ttatataata
    12121 tgattgtgta agatattgat aaaaaatcgt aataaatttt cattagtata tgctaatatt
    12181 tttttacaat tttcgtaatt aattaataga aaaatatatt ataataatat tatgaaaatt
    12241 taaaaaagta agaaagaggt aatattatga gaagtgatat aaaaaaagga atagaaggag
    12301 ctccaaagag agcgttaatg tatggaatgg gtcttactaa agaagaaatt gaaagaccat
    12361 taataggtat agtaaatgca caaaatgagg tgattcctgg tcacctacat cttgatgaaa
    12421 tagcagaagc cgcaaaaaat ggagtaagaa tgagtggtgg tttgccatta gaatttcctg
    12481 ctataggggt atgtgatggt atagctatgg ggcatgtcgg aatgaattat tcccttgctt
    12541 caagagaatt aatagcagat tcaatagaag ctatggctat ggcacatggt tttgatgctt
    12601 tggtacttat acctaattgt gacaagatag tgccaggtat gttaatggca gctgcaagac
    12661 ttaatatacc aagtattgtt gtgagtggag gtcctatgct tccaggtaaa aaaaatggaa
    12721 aagtatacga ttttaactct acaatggagg gtgttggagc atgtaaagat ggaacagtaa
    12781 gtgaagaaga attagaagag ttagctatga actcttgtcc gggatgtggt tcatgttctg
    12841 gtcttttcac agcaaatagc atgaattgtt taacagaagc tttaggcatg ggtataccat
    12901 ataatggtac tgctgcgtca cattctggag aaagaaaaag aatagcaaaa tatgcaggta
    12961 tgtatgttat ggagttactt aagaatgaca taaaacctag agatatttta acgatagatg
    13021 cttttaaaaa tgctatagct gtggatatgg caatggctgg ttctacaaat acagtacttc
    13081 acttacctgc aatagcttat gaatcaggaa tagagcttaa cttagatttt tttgatgaaa
    13141 taagtgaaaa aactccttgt ttaacaaaat taagtccaag tggaaaacat catattgaag
    13201 atttacatat ggcaggagga ataccagcta taatgaacga actttcaaaa ataaatggaa
    13261 taaatttaga ttgtaaaact gtaacgggca atactatagg ggaaaatata agagattgta
    13321 aaatagaaaa tgaagatgta atacatacat taaagaatcc atatagtaac caaggtgggc
    13381 ttgcaatatt gaaaggaaat cttgctctaa atggagctgt tgtaaaaaag tcagcagttg
    13441 cagaagaaat gttagttcat gaaggaccag caagggtttt taattcagaa gaagaagctg
    13501 taaatgctat ttttagtaaa aaaataaaca aaggtgatgt tatagttata agatatgaag
    13561 gtccaaaggg cggtccagga atgaaagaaa tgttgtctcc tacatcagca gttgcaggaa
    13621 tgggacttga taaacatgtg gcacttctta ctgatggtcg tttttcagga gcaactagag
    13681 gagcatctat aggtcatatt tctccagaag ctatggaagg tggcttaatt ggactagttg
    13741 aagaaggaga tataatttct ataaacatac cagacaaaaa attagaatta aaagtggatg
    13801 aagttgaaat agaaaagaga aaattaaaat ttaaaccttt agaaccgaaa ataaagcatg
    13861 gatacttaag tagatatgct aaattggtaa catcagcaaa tacaggagca gttttaaaat
    13921 agtaaactat atttatgcaa attagaaaaa attaagaaaa tattaattgg atatcttagg
    13981 tgttatagca ctaatgagat atccttttta tttaaaataa aaacacagca aaatcttgat
    14041 tatttcttaa agtaatgcat ctctattaaa ggaatatgag tataacatat ggatatatct
    14101 tgtcaacatt gttgaggtaa tacaactttt taaagggctg atgcagacta attttcgttc
    14161 tccctaaact atgaagaaat taaaactcag ctaattcttg acagaataaa tattaaaata
    14221 cataatgaaa aacaaacaga cagtctgttt atggaggatg atatgaatag agaagaaaaa
    14281 agtaaaaata gtaaagaaaa aattatccaa tcggcatttt tgctgttttc atctaaagga
    14341 tatgattcaa catctacaca agatattatc aatttatctg gtctatccag aggtgcaatg
    14401 tatcatcact ttaaaactaa agaagatata cttagaagtg tcacaaaaga actttattca
    14461 caaatgaata attttttaga aaatcttgtt gctgataata cccttacagc aaatgaaaaa
    14521 ataataaaat tggttgttca tagtgcgaat gattatacac gtagaaaaat gctacattgt
    14581 agctggttag aaaaaatacc atttgcttta atagaggaag ttcgtaatct caataatgta
    14641 gttgcaccca atattgctaa gataattaaa caaggtgttg aaaataaaga attttcttgt
    14701 gaatatccac aagaattagc tggaatgctc gtttttagta ttgatatttt acttgaccct
    14761 gtattattta aacgtgaata cagtgaagta tgtaataggt tggatttttt attgtttatg
    14821 ttaaaaaaaa tggatattcc tctaattgat gagtgtggta ttcaaaaatt taaggattta
    14881 tttaaataat gatagtaata aaagtgagga atagactatg ttttataatg caaaaagttg
    14941 tcaaatgatg atagacagta atacagtgaa ctatattgag tttggtagtg gtaagaagat
    15001 tctaattatt ttaccaggat taggggatgg tttatctcct ttacatggaa aaatacaggc
    15061 aattgctttt gcttttagat ataagcgatt tgcaaaagat tataaggttt atatgttcag
    15121 tagaaaaaat caaattacag aaaaatattc cacaagggat atggctaaag atcaagcaga
    15181 tataattaaa aaacttggaa ttatgaaagc gaaagtaatg ggtgtttctc aaggcggaat
    15241 gatagctcaa tatctggcaa ttgattatcc tgatttagtt gagaaacttg tgttaacagt
    15301 tacttcttct aaacaaaatg ataccatcca aaacgttatt tgtagttgga ttgatatggc
    15361 taagaaacag aattacaatg atttaatgat tgacgtagca aataaatctt attctgaaaa
    15421 atatttaaaa aaatatagat tatttattcc tcttttagga aaagtaggta aaccaaagga
    15481 tttcaataga tttattattc aagcgacttc ttgcatagaa cataattcct tttcagaatt
    15541 aaataaaata acgtgtccaa ccctaatcat aggtggtgct aatgataaaa ttgttggaaa
    15601 taaggcttct tttcatttag cagaaaaaat taaaagaagc gaaatattta tctatgaggg
    15661 attgggacac gctacatatg aagaagcaca ggatttcaac gaaagagttt tagagttttt
    15721 aaataagtaa atatatttgt taaaaatatc tatgccaatg ttgggaattt aatatggaaa
    15781 atggaaacat gaaaaggcac tggactggta ctttcaatat acctagccaa tttcttatgt
    15841 attatctact ataaatgtaa atataatttt aatatgctta tgtgttggtg tattagtaaa
    15901 acacttatac aaaaagagaa attttgtaaa tatagattat accaacattt gttaacttat
    15961 gaaaagataa tcaaaatttt tatgagcttt ttatataaaa aatagaatgt ttatat
//
LOCUS       DBGJFK010000086        15725 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.086, whole genome shotgun sequence.
ACCESSION   DBGJFK010000086 DBGJFK010000000
VERSION     DBGJFK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15725
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.086"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            52..606
                     /gene="tcdR"
                     /locus_tag="ACOIAP_003147"
     CDS             52..606
                     /gene="tcdR"
                     /locus_tag="ACOIAP_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HGZ2640024.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLNYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKTKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            924..8024
                     /gene="tcdB"
                     /locus_tag="ACOIAP_003148"
                     /gene_synonym="toxB"
     CDS             924..8024
                     /gene="tcdB"
                     /locus_tag="ACOIAP_003148"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Toxigenic strains produce this toxin (TcdB) or
                     TcdA. TcdB-producing strains are tumorigenic in mice;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HGZ2640025.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIVESAINDTLESFREN
                     LNNPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKIYLSNEYSKEI
                     DELNTYIEESLNKIKQNSGNDVRNFEEFKNGESFKLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPGYTSEH
                     FDMLDEEVQSSFESALASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTVNLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWTFDDARAKVQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSILFQKNIENSEVAYYYNPG
                     DGEIQEIDKYRIPSIISDRPKIKLTFIGHGKDEFNTDIFAGLDVDSLSTEIETAIDLA
                     KEDISSKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINNEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNLSDIELEEKVMLAECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     NEFKLIESISDSLYDLKQQNELDDSHFISFEDISKTEDGFSIRFINKETGESIFVETE
                     KEIFSEYANHIEREISNIKDTIFDTVNGKLVKKVNLDAIHEVNTLNAAFFIQSLIGYS
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     VIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTAATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHISLVETEGAFTLLDDKIMIP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTNDIDHFFSSPTITYIKPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENEGTKLLDRIRDHYKGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNNRSFIVPIITTEHIREKLSYSFHGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIDSDKIKKGDLIEGILSTLSIE
                     DNKIILNHHEINFSGDVNGSNGFISLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSFTLQDEKTIKL
                     NGVHLDESGVAEILKFMNKKGSTNTSDSLMSFLESVNIKSIFVNFLQSKINFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETTYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNNYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIISAFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPTNGGAASIGETIINDKNYYFNQSGILQTGVFS
                     TEDGLKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFEDNYRGAVEWKELDGEMYYF
                     SPETGKAFKGLNQIGDDKYYFNSDGIMQKGFVSINDKKYYFDDSGVMKVGYIEIDGKY
                     FYFAENGEMQIGVFNTSDGFKYFAHHNEDLGNEEGEAISYSGILNFNNKIYYFDYSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYVGLSLINDGQYYFNDDGIMQVGFVTINNKVFYFS
                     DSGIIESGVQNIDDNYFYIDEKGIVQIGVFDTSDEYKYFAPANTVNDNIYGQAVDYSG
                     LVRVGEDIYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEN
                     GIMRTGLISFENNDYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTQDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8146..8646
                     /gene="tcdE"
                     /locus_tag="ACOIAP_003149"
     CDS             8146..8646
                     /gene="tcdE"
                     /locus_tag="ACOIAP_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HGZ2640026.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAVLLDAMTDEM
                     NAKDEK"
     gene            8755..8886
                     /locus_tag="ACOIAP_003150"
     CDS             8755..8886
                     /locus_tag="ACOIAP_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640027.1"
                     /translation="MPRDTQVLNTYNFEASVHYYMDDKVVYQTLVHKDGAWSVGKIY"
     gene            8972..9157
                     /locus_tag="ACOIAP_003151"
                     /pseudo
     CDS             8972..9157
                     /locus_tag="ACOIAP_003151"
                     /inference="COORDINATES: protein motif:HMM:NF022413.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BhlA/UviB family holin-like peptide"
     gene            9374..>15725
                     /gene="tcdA"
                     /locus_tag="ACOIAP_003152"
                     /gene_synonym="toxA"
     CDS             9374..>15725
                     /gene="tcdA"
                     /locus_tag="ACOIAP_003152"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HGZ2640028.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFVNYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     LLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNEVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKDSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDTSVSPDTKFILNNLKLNIESSVGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDLLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKEYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNAIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIKTENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENNGTKLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNGSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQAKV
                     NGLYLNESVYSSYLDFVKNADGHHNTSNFMNLFLDNISFWKLFGFENINFVVDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLVYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEASKLVKGLININNSLFY
                     FDPIESNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNNGVMQLGVFKGPD
                     RFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSGSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAE"
BASE COUNT         6361 a         1645 c         2463 g         5256 t
ORIGIN      
        1 tgtcaatttt ttttaaaaaa tcatcattat aaaataagag aggatgattt tatgcaaaag
       61 tctttttacg aattaattgt tttagcaaga aataactcag tagatgattt gcaagaaatt
      121 ttatttatgt ttaagccatt agtaaaaaaa cttagtaggg ttttaaatta tgaagaggga
      181 gaaacagatt taataatatt ttttattgaa ttaataaaaa atattaaatt aagtagcttt
      241 tcagaaaaaa gtgatgctat tatagttaaa tatattcata aatcattatt gaataagact
      301 tttgagttat ctagaagata ttctaagact aagtttaatt ttgtagaatt tgacgaaaat
      361 atcttaaata tgaaaaataa ttatcaaagt aagtctgttt ttgaggaaga tatttgtttt
      421 ttcgaatata ttttgaaaga attatctggt attcaaagaa aagttatttt ttataaatat
      481 ttaaaaggat attctgatag agaaatatca gtgaaattaa aaatatctag acaagctgtt
      541 aataaggcta aaaatagagc atttaaaaaa ataaaaaaag actatgaaaa ttattttaac
      601 ttgtaattaa tgagtttaaa gaaatattta caatagaaat caaattttag aattaacttt
      661 attgtaaaat caataactta atctaagaat atcttaattt ttatatttta tatagaacaa
      721 agtttacata tttatttcag acaacgtctt tattcaattg aagagcaaat taatcaactg
      781 agtgtcttcg atttaaaatg ttaggaagtg aatgtatatg aaaacctaag tagatattag
      841 tatattttat aaatagaaag gaggatatat aaaagagttt tagcatttag atgtaaaaat
      901 attatagtaa aggagaaaat tttatgagtt tagttaatag aaaacagtta gaaaaaatgg
      961 caaatgtaag atttcgtact caagaagatg aatacgttgc aatattggat gctttagaag
     1021 aatatcataa tatgtcagag aatactgtag tcgaaaaata tttaaaatta aaagatataa
     1081 atagtttaac agatatttat atagatacat ataaaaaatc tggtagaaat aaagccttaa
     1141 aaaaatttaa ggaatatcta gttacagaag tattagagct aaagaataat aatttaactc
     1201 cagttgagaa aaatttacat tttgtttgga ttggaggtca aataaatgac actgctatta
     1261 attatataaa tcaatggaaa gatgtaaata gtgattataa tgttaatgtt ttttatgata
     1321 gtaatgcatt tttgataaac acattgaaaa aaactatagt agaatcagca ataaatgata
     1381 cacttgaatc atttagagaa aacttaaata accctagatt tgactataat aaatttttca
     1441 gaaaacgtat ggaaataatc tatgataaac agaaaaattt cataaactac tataaagctc
     1501 aaagagaaga aaatcctgaa cttataattg atgatattgt aaagatatat ctttcaaatg
     1561 agtattcaaa agagatagat gaacttaata cctatattga agaatcctta aataaaatta
     1621 aacagaatag tggaaatgat gttagaaact ttgaagaatt taaaaatgga gagtcattca
     1681 aattatatga acaagagttg gtagaaagat ggaatttagc tgctgcttct gacatattaa
     1741 gaatatctgc attaaaagaa attggtggta tgtatttaga tgttgatatg ttaccaggaa
     1801 tacaaccaga cttatttgag tctatagaga aacctagttc agtaacagtg gatttttggg
     1861 aaatgacaaa gttagaagct ataatgaaat acaaagaata tataccagga tatacttcag
     1921 aacattttga catgttagat gaagaagttc aaagtagttt tgaatctgct ctagcttcta
     1981 agtcagataa atcagaaata ttctcatcac ttggtgatat ggaggcatca ccactagaag
     2041 ttaaaattgc atttaatagt aagggtatta taaatcaagg gctaatttct gtgaaagact
     2101 catattgtag caatttaata gtaaaacaaa tcgagaacag gtataaaata ttgaataata
     2161 gtttaaatcc agctattagc gaggataatg attttaatac tacaacgaat acctttattg
     2221 atagtataat ggctgaagct aatgcagata atggtagatt tatgatggaa ctaggaaagt
     2281 atttaagagt tggtttcttc ccagatgtta aaactactgt taacttaagt ggccctgaag
     2341 catatgcggc agcttatcaa gatttattaa tgtttaaaga aggcagtatg aatatccatt
     2401 tgatagaagc tgatttaaga aactttgaaa tctctaaaac taatatttct caatcaactg
     2461 aacaagaaat ggctagctta tggacatttg acgatgcaag agctaaagtt caatttgaag
     2521 aatataaaag gaattatttt gaaggttctc ttggtgaaga tgataatctt gatttttctc
     2581 aaaatatagt agttgacaag gagtatcttt tagaaaaaat atcttcatta gcaagaagtt
     2641 cagagagagg gtatatacac tatattgttc agttacaagg agataaaatt agttatgaag
     2701 cagcatgtaa cttatttgca aagactcctt atgatagtat actgtttcag aaaaatatag
     2761 aaaattcaga agttgcatat tattataatc ctggagatgg tgaaatacaa gaaatagaca
     2821 agtatagaat tccaagtata atttctgata gacctaagat taaattaaca tttattggtc
     2881 atggtaaaga tgaatttaat actgatatat ttgcaggtct tgatgtagat tcattatcta
     2941 cagaaataga aacagcaata gatttagcca aagaggatat ttcttctaag tcaatagaaa
     3001 taaatttatt aggatgtaat atgtttagct actctatcaa cgtagaagag acttatcctg
     3061 gaaagttatt acttaaagtt aaagataaaa tatcagaatt aatgccatct ataagtcaag
     3121 actctattat agtaagtgca aatcaatatg aagttagaat aaataatgaa ggaagaagag
     3181 aattattgga tcattctggt gaatggataa ataaagaaga aagtattata aaggatattt
     3241 catcaaaaga atatatatca tttaatccta aagaaaataa aattacagta aaatctaaaa
     3301 atttacctga gctgtctaca ttattacaag aaattagaaa taattctaat ttaagtgata
     3361 ttgaactaga agaaaaagta atgttagcag aatgtgaaat aaatgttatt tcaaatatag
     3421 atacacaaat tgttgaggaa aggattgaag aagctaagaa tttaacttct gactctatta
     3481 attatataaa aaatgaattt aaactaatag aatctatttc tgattcctta tacgatttaa
     3541 aacaacaaaa tgaattggat gattctcatt ttatatcttt tgaggatata tcaaagacag
     3601 aagatggatt tagtataaga tttattaata aagaaactgg agaatctata tttgtagaaa
     3661 ctgaaaaaga aattttttct gaatatgcta atcatataga gagagaaatt tctaatataa
     3721 aagatactat atttgatact gtaaatggta agttagtaaa aaaagtgaat ttagatgcta
     3781 tacatgaagt aaatacttta aatgctgcat tttttataca atcattaata ggatatagta
     3841 gttctaaaga atctcttagt aatttaagtg tagcaatgaa agttcaagtt tatgctcaat
     3901 tatttagcac tggtttaaat actattacag atgcagccaa agttgttgaa ttagtatcaa
     3961 ctgcattaga tgaaactata gacttacttc ctacattatc tgaaggatta cctgtaattg
     4021 caactatcat agatggtgta agtttaggtg cagcaatcaa agagttaagt gaaactagtg
     4081 acccattatt aagacaagaa atagaagcta agataggtat aatggcagta aacttaacag
     4141 cagctacaac tgcaatcatt acttcatctt tagggatagc tagtggattt agtatacttt
     4201 tagttccttt agcaggtatt tcagcaggta taccaagctt agtaaataat gaacttgtac
     4261 ttagagataa ggcaacaaag gttgtagatt attttaaaca tatttcatta gttgaaactg
     4321 aaggagcatt tactttatta gatgataaaa taatgatacc acaagacgat ttagtgatat
     4381 cagaaataga ttttaataat aattcaatag ttttaggtaa atgtgaaatc tggcgaatgg
     4441 aaggtggctc aggtcataca gtaacaaatg atatagatca cttcttttca tcaccaacaa
     4501 taacatatat aaaaccacac ttatctatct atgatgtatt ggaagtacaa aaagaagaac
     4561 ttgatttgtc aaaagattta atggtattac ctaatgctcc aaatagagta tttgcttggg
     4621 aaacaggatg gacaccaggt ttaagaagtt tagaaaatga gggtacaaaa ctgttagacc
     4681 gtataagaga tcactacaaa ggtgagtttt attggagata tttcgctttt atagctgatg
     4741 ctttaataac aacattaaaa ccacgatatg aagatactaa tataaggata aatttagata
     4801 gtaacaatag aagttttata gttccaataa taactacaga acatataaga gaaaaattat
     4861 catattcttt ccatggctca ggaggaacat atgcattatc tctttctcaa tataatatgg
     4921 gtataaatat agaattaagt gaaagtgatg tttggattat agatgttgat aatgttgtga
     4981 gagatgtaac tatagactct gataaaatta aaaaaggtga tttaatagaa ggtattctat
     5041 ctacactaag tattgaagat aataaaatca tcttaaatca tcatgagatt aatttttctg
     5101 gagatgtaaa tggaagtaat ggatttattt ctttaacatt ttcaatttta gaaggaataa
     5161 atgcaattat agaagttgat ttattatcta aatcatataa attacttatt tctggcgaat
     5221 taaaaatatt gatgttaaat tcaaatcata ttcaacagaa aatagattat ataggattca
     5281 atagcgaatt acagaaaaat ataccatata gctttgtaga tagtgaagga aaagagaatg
     5341 gttttattaa tggttcaaca aaagaaggtt tatttgtatc tgaattacct gatgtagttc
     5401 ttataagtaa ggtttatatg gatgatagta agccttcatt tggatattat agtaataatt
     5461 tgaaagatgt caaagttata actaaagata atgttaatat attaacaggt tattatctta
     5521 aggatgatat aaaaatctct ctttctttta ctctacaaga tgaaaaaact ataaaattaa
     5581 atggtgtgca tttagatgaa agtggagtag ctgagatttt gaagttcatg aataaaaaag
     5641 gtagtacaaa tacttcagat tctttaatga gttttttaga aagtgtgaat ataaaaagta
     5701 ttttcgttaa tttcttacaa tctaaaatta actttatatt agatgctaat tttataataa
     5761 gtggtactac ttctattggt caatttgagt ttatttgtga tgaaaatgat aatatacaac
     5821 catatttcat taagtttaat acactagaaa ctacttatac tttatatgta ggaaatagac
     5881 aaaatatgat agtagaacca aattatgatt tagatgattc tggagatata tcttcaactg
     5941 ttatcaattt ctctcaaaag tatctttatg gaatagacag ttgtgttaat aaagttgtaa
     6001 tttcaccaaa tatttataca gatgaaataa atataacgcc tgtatatgaa acaaataata
     6061 attatccaga agttattgta ttagatgcaa attatataaa cgaaaaaata aatgttaata
     6121 tcaatgatct atctatacga tatgtatgga gtaatgatgg taatgatttt attcttatgt
     6181 caactagtga agaaaataag gtgtcacaag ttaaaataag attcgttaat gtttttaaag
     6241 ataagacttt ggcaaataag ctatctttca actttagtga taagcaagat gtgcctgtga
     6301 gtgaaataat ctcagcattt acaccttcat attatgagga tggattgatt ggctatgatt
     6361 tgggtctagt ttctttatat aatgaaaaat tttatattaa taactttgga atgatggtat
     6421 ctggattaat atatattaat gattcattat attactttaa accaccagta aataatttga
     6481 taactggatt tgttactgta ggtgatgata agtattactt taatccaact aatggtggag
     6541 ctgcctcaat tggagagaca ataattaatg acaaaaatta ttatttcaac caaagtggaa
     6601 tcttacaaac aggtgtattt agtacagaag atggacttaa atattttgcc ccagctaata
     6661 cacttgatga aaacctagaa ggagaagcaa ttgattttac tggaaaatta attattgacg
     6721 aaaatattta ttattttgaa gataattata gaggagctgt agaatggaaa gaattagatg
     6781 gtgaaatgta ctattttagc ccagaaacag gcaaagcttt taaaggtcta aatcaaatag
     6841 gtgatgataa atactatttt aattctgatg gaattatgca aaaaggattt gttagtataa
     6901 atgataagaa atattatttt gatgattctg gtgttatgaa agtgggttat attgaaatag
     6961 atggcaagta tttctacttt gctgaaaatg gagaaatgca aataggagta tttaatacat
     7021 cagatggatt taaatatttt gctcatcata atgaagacct aggaaatgaa gaaggtgaag
     7081 caatttcata ttctggtata ttaaatttca ataataaaat ttactatttt gattattcat
     7141 ttacagctgt agttggatgg aaagatttag aggatggttc aaagtattat tttgatgaag
     7201 atacagcaga agcatatgta ggtttatcat taatcaatga tggtcaatat tattttaatg
     7261 atgatggaat tatgcaagtt ggatttgtca ctataaataa taaagttttc tacttctctg
     7321 attctggaat tatagaatct ggagtacaaa atatagatga taattatttc tatatagatg
     7381 agaagggtat agttcaaatt ggcgtatttg atacttcaga tgaatataaa tactttgcac
     7441 ctgctaatac tgtaaatgat aatatttacg gacaagcagt tgactatagc ggtttagtta
     7501 gagttggtga agatatatat tattttggag aaacctatac aattgagact ggatggatat
     7561 atgatatgga aaatgaaagt gataaatatt atttcaatcc agaaactaaa aaagcatgca
     7621 aaggtattaa tttaattgat gatataaaat attattttga tgagaatggc ataatgagaa
     7681 cgggtcttat atcatttgaa aataatgatt attactttaa cgagaatggt gaaatgcaat
     7741 ttggttatat aaatatagaa gataagatgt tttattttgg tgaagatggt gtcatgcaga
     7801 ttggagtatt taatacgcaa gatggattta aatactttgc acatcaaaat actttggatg
     7861 agaattttga gggagaatca ataaactata ctggttggtt agatttagat gaaaagagat
     7921 attattttac agatgaatat attgcagcaa ctggttcagt tattattgat ggtgaggagt
     7981 attattttga tcctgataca gctcaattag tgattagtga atagataaaa atatgttaaa
     8041 tatatcctct tatacttaaa tatataaaaa taaacaaaat gatacactac ataaagtgtt
     8101 ctatctaata tgaagattta ccaataaaaa ggtgaactat gatgaattca cagtagttca
     8161 cctttttata tttctaatgg taacaaaata tttttttata taaacctagg aggcgttatg
     8221 aatatgacaa tatctttttt atcagagcat atatttataa agttagtaat tttaactata
     8281 tcatttgata cattattagg atgtttaagt gcaataaaaa gtcgtaaatt taattctagt
     8341 tttggaatag atggaggaat cagaaaagta gcaatgatag catgtatatt ttttttatca
     8401 gtagttgaca ttcttacaaa gtttaacttt ttatttatgt taccacaaga ttgtatcaat
     8461 tttttaagac taaaacatct tggaatatct gaatttttct ctattttatt tattttatat
     8521 gaaagtgtaa gtatattaaa aaatatgtgc ttatgtggat taccagtacc taagagatta
     8581 aaggaaaaaa tagcagtttt actagatgca atgacagatg aaatgaatgc taaggatgaa
     8641 aagtaagtac tggtagatat aataaagata ttaacaaata aaaagtgtta tccaaataag
     8701 aatagctgaa agttatcata attcatgaaa ctgataatga aaacgaggga gcagatgcca
     8761 agagacacac aagtattaaa tacatataat ttcgaagcaa gtgttcatta ctatatggat
     8821 gacaaggtag tatatcaaac attggttcac aaagatggtg catggtcagt tggtaaaatc
     8881 tattaagcta cattagttac agatatcaca aactataata gttaaacata gaaatatgtg
     8941 taaattgtga tggaaattat tcaaaaacac aaaaatacgt gatgaaggac aaaatgatag
     9001 agaaaataag tatcaaacct taataaatga tttaattgat agtttaaaag ttataggaaa
     9061 aatatataaa gaaataaaaa cattaaaaaa atataagata tgtttacaaa ttactatcag
     9121 acaatctcct tatctaatag aagagtcaat taactaattg agtatcttta aattgaaatg
     9181 ttaggaagtg atttaaatat gaaaacttaa attataaaaa atcaatatta atttattttt
     9241 aaaaaataga aaggagtgta taagatttat tttcaaagtt taaaaaaaag aaaatcaatt
     9301 taaatttcag aaggaataaa tgtggttata gaagtggatt tattatcaaa aataataata
     9361 ctaggaggtt tttatgtctt taatatctaa agaagagtta ataaaactcg catatagcat
     9421 tagaccaaga gaaaatgagt ataaaactat actaactaat ttagacgaat ataataagtt
     9481 aactacaaac aataatgaaa ataaatattt acaattaaaa aaactaaatg aatcaattga
     9541 tgtttttatg aataaatata aaaattcaag cagaaataga gcactctcta atctaaaaaa
     9601 agatatatta aaagaagtaa ttcttattaa aaattccaat acaagccctg tagaaaaaaa
     9661 tttacatttt gtatggatag gtggagaagt cagtgatatt gctcttgaat acataaaaca
     9721 atgggctgat attaatgcag aatataatat taaactgtgg tatgatagtg aagcattctt
     9781 agtcaataca ctaaaaaagg ctatagttga atcttctacc actgaagcat tacagctact
     9841 agaggaagag attcaaaatc ctcaatttga taatatgaaa ttttacaaaa aaaggatgga
     9901 atttatatat gatagacaaa aaaggtttgt aaattattat aaatctcaaa tcaataaacc
     9961 tacagtacct acaatagatg atattataaa gtctcatcta gtatctgaat ataatagaga
    10021 tgaaacttta ttagaatcat atagaacaaa ttctttgaga aaaataaata gtaatcatgg
    10081 gatagatatc agagctaata gtttgtttac agaacaagag ttactaaata tttatagtca
    10141 ggagttgtta aatcgtggaa atttagctgc agcatctgac atagtaagat tattagccct
    10201 aaaaaatttt ggcggagtat atttagatgt tgatatgctt ccaggtattc actctgattt
    10261 atttaaaaca atatctagac ctagctctat tggactagac cgttgggaaa tgataaaatt
    10321 agaggctatt atgaagtata aaaaatatat aaataattat acatcagaaa actttgataa
    10381 acttgatcaa caattaaaag ataattttaa actcattata gaaagtaaaa gtgaaaaatc
    10441 tgagatattt tctaaattag aaaatttaaa tgtatctgat cttgaaatta aaatagcttt
    10501 cgctttaggc agtgttataa atcaagcctt gatatcaaaa caaggttcat atcttactaa
    10561 cctagtaata gaacaagtaa aaaatagata tcaattttta aaccaacacc ttaacccagc
    10621 catagagtct gataataact tcacagatac tactaaaatt tttcacgatt cattatttaa
    10681 ttcagctacc gcagaaaact ctatgttttt aacaaaaata gcaccatact tacaagtagg
    10741 ttttatgcca gaagctcgct ccacaataag tttaagtggt ccaggagctt atgcatcagc
    10801 ttactatgat ttcataaatt tacaagaaaa tactatagaa aaaactttaa aagcatcaga
    10861 tttaatagaa tttaaattcc cagaaaataa tctatctcaa ttgacagaac aagaaataaa
    10921 tagtctatgg agctttgatc aagcaagtgc aaaatatcaa tttgagaaat atgtaagaga
    10981 ttatactggt ggatctcttt ctgaagacaa tgaggtagac tttaataaaa atactgccct
    11041 cgataaaaac tatttattaa ataataaaat tccatcaaac aatgtagaag aagctggaag
    11101 taaaaattat gttcattata taatacagtt acaaggagat gatataagtt atgaagcaac
    11161 atgcaaccta ttttctaaaa atcctaaaaa tagcattatt atacaacgaa atatgaatga
    11221 aagtgcaaaa agttactttt taagtgatga tggagaatct attttagaat taaataaata
    11281 taggatacct gaaagattaa aaaataagga aaaagtaaaa gtgaccttta ttggacatgg
    11341 taaagatgaa ttcaacacaa gcgaatttgc tagattaagt gtagattcac tttccaatga
    11401 gataagttca tttttagata ccataaaatt agatatatca cctaaaaatg tagaagtaaa
    11461 cttgcttgga tgtaatatgt ttagttatga ttttaatgtt gaagaaactt atcctggtaa
    11521 gttactatta agtattatgg acaaaattac ttccacttta cctgatgtaa ataaagattc
    11581 tattactata ggagcaaatc aatatgaagt aagaattaat agtgagggaa gaaaagagct
    11641 tctagctcac tcaggtaaat ggataaataa agaggaagct attatgagcg atttatctag
    11701 taaagaatac attttttttg actctataga taataagcta aaagcaaagt ccaagaatat
    11761 tccaggatta gcgtcaatat cagaagatat aaaaacattg ttacttgata caagtgttag
    11821 tcctgataca aaatttattt taaataatct taagcttaat attgaatctt ctgttggtga
    11881 ttacatttat tatgaaaaat tagaacctgt taaaaatata atccacaatt ctatagatga
    11941 tttaatagat gagttcaatc tacttgaaaa tgtatctgat gaattatatg aattaaaaaa
    12001 attaaataat ctagatgaga agtatttaat atcttttgaa gatatctcaa aaaataattc
    12061 aacttattct gtaagattta ttaacaaaag taatggtgaa tcagtttatg tagagacaga
    12121 aaaagaaatt ttttcaaaat atagcgaaca tattacaaaa gaaataagta ctataaaaaa
    12181 tagtataatt acagatgtta atggtaattt attagataat atacagttag atcatacatc
    12241 tcaagttaat acattaaacg cagcattctt tattcaatca ttaatagatt atagtagcaa
    12301 taaagatcta ctgaatgatt taagtacctc agttaaggtt caactttatg ctcaactatt
    12361 tagtacaggt ttaaatacta tatatgactc tatccaatta gtaaacttaa tatcaaatgc
    12421 agtaaatgat actataaatg tactacctac aataacagag gggataccta ttgtatctac
    12481 tatattagac ggaataaact taggtgcagc aattaaggaa ttactagacg aacatgaccc
    12541 attactaaaa aaagaactag aagctaaggt gggtgtttta gcaataaata tgtcattatc
    12601 tatagctgca acggtagctt caattgttgg aataggtgct gaagttacta ttttcttatt
    12661 acctatagct ggtatatctg caggaatacc ttcattagtt aataatgaat taatattgca
    12721 tgataaggca acttcagtgg taaattattt taatcatttg tctgaatcta aagaatatgg
    12781 ccctcttaaa acagaagatg ataaaatttt agttcctatt gatgatttag taatatcaga
    12841 aatagatttt aataataatg cgataaaact aggaacatgt aatatattag caatggaggg
    12901 gggatcagga cacacagtga ctggtaatat agatcacttt ttctcatctc catctataag
    12961 ttctcatatt ccttcattat caatttattc tgcaataggt ataaaaacag aaaatctaga
    13021 tttttcaaaa aaaataatga tgttacctaa tgctccttca agagtatttt ggtgggaaac
    13081 tggagcagtt ccaggtttaa ggtcattaga aaataatgga actaaattac ttgattcaat
    13141 aagagattta tacccaggca aattttactg gagattctat gcctttttcg attatgcaat
    13201 aactacatta aaaccagtgt atgaagacac taatattaaa attaaactag ataaagatac
    13261 tagaaacttc ataatgccaa ctataactac taacgaaatt agaaacaaat tatcttattc
    13321 atttgatgga gcaggaggaa cttactcttt attattatct tcgtatccaa tatcaacaaa
    13381 tataaattta tctaaagatg atttatggat atttaatatt gataatgaag taagagaaat
    13441 atctatagaa aatggtacta ttaaaaaagg aaagttaata aaagatgttt taagtaaaat
    13501 tgatataaat aaaaataaac ttattatagg caatcaaaca atagattttt caggcgatat
    13561 agataataaa gacagatata tattcttgac ttgtgagtta gatgataaaa ttagtttaat
    13621 aatagaaata aatcttgttg caaagtctta tagtttgtta ttgtctggag ataaaaatta
    13681 tttgatatcc aatttatcta atactattga gaaaatcaat actttaggtc tagatagtaa
    13741 aaatatagcg tacaattaca ctgatgaatc taataataaa tattttggag ctatatctaa
    13801 aacaagtcaa aaaagcataa tacattataa aaaagacagt aaaaatatat tagaatttta
    13861 taatggcagt acattagaat ttaacagtaa agattttatt gctgaagata taaatgtatt
    13921 tatgaaagat gatattaata ctataacagg aaaatactat gttgataata atactgataa
    13981 aagtatagat ttctctattt ctttagttag taaaaatcaa gcaaaagtaa atggattata
    14041 tttaaatgaa tccgtatact catcttatct tgattttgtg aaaaatgcag atggacacca
    14101 taatacttct aattttatga atttattttt ggacaatata agtttctgga aattgtttgg
    14161 gtttgaaaat ataaattttg tagtcgataa atactttacc cttgttggta aaactaatct
    14221 tggatatgta gaatttattt gtgacaataa taaaaatata gatatatatt ttggtgaatg
    14281 gaaaacatcg tcatctaaaa gcactatatt tagcggaaat ggtagaaatg ttgtagtaga
    14341 gcctatatat aatcctgata cgggtgaaga tatatctact tcactagatt tttcttatga
    14401 acctctctat ggaatagata gatatatcaa taaagtattg atagcacctg atttatatac
    14461 aagtttaata aatattaata ccaattatta ttcaaatgag tactaccctg agattatagt
    14521 tcttaaccca aatacattcc acaaaaaagt aaatataaat ttagatagtt cttcttttga
    14581 gtataaatgg tctacagaag gaagtgactt tattttagtt agatacttag aagaaagtaa
    14641 taaaaaaata ttacaaaaaa taagaatcaa aggtatctta tctaatactc aatcatttaa
    14701 taaaatgagt atagatttta aagatattaa aaaactatca ttagtatata taatgagtaa
    14761 ttttaaatca tttaattctg aaaatgaatt agatagagat catttaggat ttaaaataat
    14821 agataataaa acttattact atgatgaagc tagtaaatta gttaaaggat taatcaatat
    14881 aaacaattca ttattctatt ttgatcctat agaatctaac ttagtaactg gatggcaaac
    14941 tatcaatggt aaaaaatatt attttgatat aaatactgga gcagctttaa ctagttataa
    15001 aattattaat ggtaaacact tttattttaa taataatggt gtgatgcagt taggagtatt
    15061 taaaggacct gatagatttg agtattttgc acctgccaat actcagaata ataacataga
    15121 aggtcaggct atagtttatc aaagtaaatt cttaactttg aatggcaaaa aatattattt
    15181 tgataatgac tcaaaagcag tcactggatg gagaattatt aacaatgaga aatattactt
    15241 taatcctaat aatgctattg ctgcagtcgg attgcaagta attgacaata ataagtatta
    15301 tttcaatcct gacactgcta tcatctcaaa aggttggcag actgttaatg gtagtagata
    15361 ctactttgat actgataccg ctattgcctt taatggttat aaaactattg atggtaaaca
    15421 cttttatttt gatagtgatt gtgtagtgaa aataggtgtg tttagtggct ctaatggatt
    15481 tgaatatttt gcacctgcta atacttataa taataacata gaaggtcagg ctatagttta
    15541 tcaaagtaaa ttcttaactt tgaatggtaa aaaatattac tttgataata actcaaaagc
    15601 agttactgga tggcaaacta ttgatagtaa aaaatattac tttaatacta acactgctga
    15661 agcagctact ggatggcaaa ctattgatgg taaaaaatat tactttaata ctaacactgc
    15721 tgaag
//
LOCUS       DBGJFK010000087        15360 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.088, whole genome shotgun sequence.
ACCESSION   DBGJFK010000087 DBGJFK010000000
VERSION     DBGJFK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.088"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            602..1069
                     /locus_tag="ACOIAP_003153"
     CDS             602..1069
                     /locus_tag="ACOIAP_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGZ2640029.1"
                     /translation="MKFGSVLIVVEDIEKSKRFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKGDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSMDEVAKRMDVTVEYIESVLD"
     gene            complement(1184..1378)
                     /locus_tag="ACOIAP_003154"
     CDS             complement(1184..1378)
                     /locus_tag="ACOIAP_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640030.1"
                     /translation="MEDLINKKLVITPEAKKLIQNYTWKDNIRELQNVTSYLNIMCED
                     IVLEKDLPPNLRSSSNKTHH"
     gene            complement(1362..1901)
                     /locus_tag="ACOIAP_003155"
                     /pseudo
     CDS             complement(1362..1901)
                     /locus_tag="ACOIAP_003155"
                     /inference="COORDINATES: protein motif:HMM:NF012385.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            2561..3214
                     /locus_tag="ACOIAP_003156"
     CDS             2561..3214
                     /locus_tag="ACOIAP_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HGZ2640031.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCILLNKQENNVCNIKA
                     IRNFSEIYSISRKSRYHSLLRLTEKGIIKKMGNTYEILNYDELHRLAFEVKEFLEDE"
     gene            complement(3354..4730)
                     /locus_tag="ACOIAP_003157"
     CDS             complement(3354..4730)
                     /locus_tag="ACOIAP_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2640032.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVGNIRKVTGLTCMLA
                     IILSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAISTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYFYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAVGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(4746..6659)
                     /locus_tag="ACOIAP_003158"
     CDS             complement(4746..6659)
                     /locus_tag="ACOIAP_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGZ2640033.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIDMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELKPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLELEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            6795..7427
                     /locus_tag="ACOIAP_003159"
     CDS             6795..7427
                     /locus_tag="ACOIAP_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGZ2640034.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            7566..8105
                     /locus_tag="ACOIAP_003160"
     CDS             7566..8105
                     /locus_tag="ACOIAP_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HGZ2640035.1"
                     /translation="MIFVEELWEKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGVDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(8271..8441)
                     /locus_tag="ACOIAP_003161"
     CDS             complement(8271..8441)
                     /locus_tag="ACOIAP_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HGZ2640036.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDASSCIDCGSC
                     AGACPVDAPQPE"
     gene            8726..9793
                     /locus_tag="ACOIAP_003162"
     CDS             8726..9793
                     /locus_tag="ACOIAP_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGZ2640037.1"
                     /translation="MKNKLIYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFKKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSVANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVVGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPHIIPTSITSSSSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNQ"
     gene            9963..11864
                     /gene="cooS"
                     /locus_tag="ACOIAP_003163"
     CDS             9963..11864
                     /gene="cooS"
                     /locus_tag="ACOIAP_003163"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0043885 - anaerobic carbon-monoxide
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006091 - generation of precursor
                     metabolites and energy [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HGZ2640038.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVIKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFRLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            11857..12330
                     /locus_tag="ACOIAP_003164"
     CDS             11857..12330
                     /locus_tag="ACOIAP_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HGZ2640039.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            12305..13531
                     /locus_tag="ACOIAP_003165"
     CDS             12305..13531
                     /locus_tag="ACOIAP_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGZ2640040.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENIYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVNWIAGKTVKGIDVNKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLREGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIILDDSKNVK
                     GVAFSNGEILDADMVIVATGVKPNADFLDETGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMAGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGLNDYKKFIFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFKIKENGEFCYSV"
     gene            complement(13684..14871)
                     /locus_tag="ACOIAP_003166"
     CDS             complement(13684..14871)
                     /locus_tag="ACOIAP_003166"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2640041.1"
                     /translation="MNITKNFLKDYLERFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            15144..15242
                     /locus_tag="ACOIAP_003167"
     CDS             15144..15242
                     /locus_tag="ACOIAP_003167"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="HGZ2640042.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIID"
BASE COUNT         5740 a         1841 c         2409 g         5370 t
ORIGIN      
        1 ttattttatt tataaaaatt aggattaatt tataatgtta atattaaaaa acaaatttat
       61 ttaaatttaa aattttgttt attattaaag cgtaaatata attattaata atatatagta
      121 tttgtaataa aatatcaata attagaaaga ttatgaaaat taaattagaa gttactaaaa
      181 actatatttt tattacttag aatacttgaa taatttcttt aatcatgtaa aatacatatg
      241 cttgtaatat ttaaaaagag tattaatatt attagtgtat attaatattt acttgaaatt
      301 aaaagaatat agatatttca atattctaaa atagtatttt tgttttagaa gttagataat
      361 aatataatct acaaaaacag gaagtttttt agttaaattt atatgtattt taattttgaa
      421 tctaaaagtg tagagatgtc tgttttttac aagagtaaag caaatattat atgatataat
      481 caactcaact atctaaataa gacttacaat tttcttgttt atatcatgtc ttattgaaat
      541 atgtatagtt taattttact tttgtaatga aaataaaata tgtgtatatc aaggaggaaa
      601 tatgaagttt ggaagtgttt taatagtggt tgaagatatt gaaaaatcaa aaaggtttta
      661 ttatgatgtt ttgggattaa aggtaatctg tgattttgga gaaaatgttg tattagaagg
      721 gaatatatca ttacaagaaa aaaagctttg gttagagttt attaataagg gtgacagtga
      781 agttaagttc aatggaaatg atgctgagtt atattttgag gaagataatt ttgatacttt
      841 tgttgaaaga ttgagtacaa tgaaagatat agattatgtt catctagcta tagagcatag
      901 gtggggtcaa agagcaatta gattttatga tttagatggg catattattg aggttggaga
      961 aactatgtca tctgtgtgta gacgtttttt agatagtggt ctttcaatgg atgaggtagc
     1021 taaaagaatg gatgtaactg ttgaatatat tgaatcagtt ttagactaga tggattatgc
     1081 taaaataaaa ctgaggtgag ggctgtaagt aaacttgtgt gaaaataaat ttacttacag
     1141 tttttgtttt tgtaaaatat atcattctta ctatatttta attttaatga tgggttttat
     1201 tacttgaaga ccttaagttt ggaggtaagt ctttctctaa tacaatatct tcacacataa
     1261 tatttaaata agatgtaaca ttttgaagtt ctcttatatt atccttccac gtataatttt
     1321 gtataagttt ttttgcttct ggtgtgatta ctaatttctt attaattaaa tcttccataa
     1381 taattaatat atcttctttc tcttacaaga ggtatattta ttggaattgt atttaaacga
     1441 taatataaat tctctctaaa atggctatta tcaataattt gttccaaatt cttatttgta
     1501 gcagatataa ttctaacacc tatattaatt atattgtgag aaccaacagg cattatctgt
     1561 ttttcttgaa gaactttaag taattttgtt tgtaattcta agggcatata gcctatttca
     1621 tctaagaata ttattccatt attagcaggc taaaataatc cttattttcc atcttttaga
     1681 cctccagtaa aagttctttt gtcatatccg aatatctcat tttctaataa attttcagga
     1741 acagttgtac aatttactgc tataaagggt tgattttttc tatttgagtt gttatgtata
     1801 gactgagcta tgagtttttt accggttcta ctttcacctc tgacaagtat gcttaagtca
     1861 gatttagaaa ccttcttagt taaatctata tattcgagca ttttggggct agttgttttt
     1921 atatccttaa atgtatattt tgctatttgt cctttttctt ttaatttttt agtgagattt
     1981 tgttctaaat tttttaattt atataatctc caaaaactaa tttaaaatta ttttctaaaa
     2041 aatctgttaa atcttttcta ttatcattta taagaagcac tgattttttt attgatttct
     2101 ccttatataa taaatagttt ccaacaaaat agttgtataa agcaatctaa ttttgataat
     2161 ttaaatttat caaataaaaa agaaagtgtc tataatgacc ttacaaaagt tgcattaaga
     2221 cactttcctt cttataatta aatcttgtca ccaaatcccc ctaattgttg cctaaaatct
     2281 aaactgtatg tatatttttc atttctattc gattaaatta taatatacac ccaaaaaaat
     2341 ttattttaat aaattctatt gataatataa ttttataaat atagaattgt attaaaataa
     2401 attatatatg aaaatatata tgtataagtt tattctgcgt gagtagaatg aatttgtcaa
     2461 gtttaattta actataatca tatcttttat taaaaataat ataaattaaa acatataaat
     2521 aaaatatttt atacaatata ttgtaaagga ggtaactttg atgaaagcag aaaaaacaag
     2581 tatatatcca attattaaaa ataatttaaa caaaatatca attgttgaat ataaaaaggg
     2641 tcaaagattt gtagcatcag ataaagactt gcaagaagta ttctttataa tagagggagt
     2701 tgcattagtg gagtgcacta ctagaggagg gaataaattt cttgttgaca ttgtacctga
     2761 aaatgaattt ataggcaaaa tcagttatat atatgaacat aatttgaaat gtgatatatt
     2821 tgcaaaaacc aatataaaat tatttcgatt tgaaaaaaat gtatttgaag agttttatct
     2881 taaaccagat tttattgcac tatttcacag aaaatgtaca agaagaatat atgaattata
     2941 taaaactaga atggtaagag aactattttc ttgtacagag gttattgcct attgtatatt
     3001 attaaataaa caagaaaata atgtctgcaa tataaaagcc attcgtaatt tcagtgaaat
     3061 ctattcaatt agtagaaaaa gtagatacca ttctctgttg aggttaactg aaaaaggtat
     3121 aataaaaaaa atgggtaata catatgaaat tttaaattat gatgaattac atagattggc
     3181 atttgaagta aaagagtttt tggaggatga ataaagatta ttacttaatc aaaataaggt
     3241 ataataattt ctgtaaaaaa tagaaatagt ctcactgaaa atcaaaaata ctttagttgt
     3301 tttcaatgag actgtttaga aatattgtat acttacaatg tatagtatag ttattagtca
     3361 atttccttta ctatgttaat agcccatttt ttagataatg ctctaggaac accaaatata
     3421 aacttaacaa cttcttcact gtaagtgagt agaacaagta caaatatagg tgcaccttta
     3481 aatgcagcta taaaagttag aggaatagaa gctagccaca tacatcctaa ttctaaaaat
     3541 agagcatatt tagtatctcc tccacttctt aaaataccaa ttataaccaa tgtattaaaa
     3601 gatttgagag ccattagtat tcccattata aagaatatct tagttatatc agaagctaag
     3661 ctatcagaaa cactaaacat ttttaataat aatggtatat ttaaaattaa aataattcca
     3721 agtattaaac cagctgaaaa tacaagtata gaaaactttt tagcatattc aatggctctt
     3781 ttaatatggt cagctccaag ttcatttcca agcataatag atgcaccaga tgcgatacat
     3841 acagcagtca ttatgaagaa attgcctgta ctggttgcta tctggctggc tgctatagca
     3901 gaagtaccag ctcttgcata tgcaacagaa tacagcacag ttccaactgc ccatacagag
     3961 tcatttacaa atataggaaa gctttttgat gaaaaagatt ttataaaaat tttatcaata
     4021 gcttttagat ttttcagacc aaattttaat atatagtctt ttttataaaa gtaaacataa
     4081 gtaatcatta aaattaattc acatattcta gcaataacag tagctagagc agcacctttt
     4141 acacccagtg caggaagacc gaagttacca aagataaatc cataatttaa aataacattt
     4201 gttacaagtg caaatgcact acaaatcata cctaacttag gatttctaac acctcttgaa
     4261 ccagtactaa atacagtact tatagcaatt aatggataac taaatactgc aatactaaag
     4321 taatctatac aaagttttac aacttcagaa tcatacgaaa atatgtgtat aattggcttt
     4381 ggtgttagta aagcaggaat aacaaataca aaacttaaaa taatggctaa catacaagta
     4441 agacctgtaa cttttcttat attgccaaca tccttctttc cataaaactg tgaaataaaa
     4501 actccagcac ctcctgtgat gccagataag gacatattaa aaagaaagaa aaattggttt
     4561 gcaactccaa ctgaagctac agatgtttct cctaaactac ttatcataat tgtatctatt
     4621 acatttacag aagtagaaat taaattctgt ataataatag gtatacataa agatagaagt
     4681 attttataaa atcttttatt ttcgtctttt aaagaaaata gttcttgcaa ataatcctct
     4741 cctttttaca taaattcttc ccactcatca tatagagagg caaggttatt ttctaaatta
     4801 attttttctt gactaacttc tttagcctta tctggattag agtatacttc ttcttgacat
     4861 aaaagtatat ctaatttttc aatttcaagc tctaactttt caatttcttt ttctatattt
     4921 tgtcttttta ttctattttt cttttctatt tctctttgtt ctctctcttt tcttttttca
     4981 tcttttattt gagttctagt tttttcttct ttttcttcta taatactcat ttcttggatt
     5041 tgcctttttt tatctatata ataatcataa tttcctagat attcagtaat tccattttca
     5101 tctaaaacta aaattttatc aacaacagta tttagaaagt atctatcatg tgatattgta
     5161 aatatagttc catcataatt agttaatgcc tcttcaagga cttccttaga atcaatatct
     5221 aggtgattag taggctcatc taataataat aagtttgcat ttgatagtat aagtttaagt
     5281 attgcaactc tagctctttc tccaccgctc aatgtagaaa ttttcttaaa aacttcttca
     5341 tctacaaata aaaatgctcc taacatattt ctcaaagtag tttgagtaag atgagtatta
     5401 ttttcccaaa tttcatcaat tattgtatta tctaaattaa gagttttttg ttcctgatgg
     5461 aagtaggaaa catggacatt agttccaaat ttaatattgc cactaagagg tttcagttca
     5521 ttagttatta ttttaaataa tgtagattta ccaacaccat ttgcacctat aagagcaact
     5581 ttttcccctc tatatatatc taaatccaag tctttaaaaa gtattctttc tccataaccc
     5641 atagatacat ctctaatttg aagaacatca ttaccactct ggacagaagg cgtaaattgt
     5701 atacgagctt tttttctata agcttctggt ttatctaaaa cgtctacctt gtctaatgct
     5761 ttttctttac ttcttgcacg ctttaggtgt ttttctctac cataagcttt tagtctttca
     5821 attgattctt cttgcttttt tatttctttt tgttggtctt caaatttctt aagttctagt
     5881 tctttttcta ttttagataa ctcaacaaat ttagagtagt taccattata tactttaagt
     5941 tttttgttat gaacttcaaa aattctattt acagattggt ctaagaaata tctatcatga
     6001 gatattaaca tgacagtccc tttatattgt tttaaaaata cttctaacca ttctattgct
     6061 tcagagtcta agtggttagt aggttcatca agtaacaata gagttggttt cttaagaagt
     6121 aattttccta aaagaactct agttttttca ccaccagaaa gtatacttat tggcttatcc
     6181 atatcattgt cactaaatcc taatcctttt agaactcctt tggcttcaga cttatatcca
     6241 tatccattta aatctgaaaa taattccagt ttatgtgaat attcatccat aattttttct
     6301 ataattggag aatttgtttt tgtactttct tcagatattt taacctccaa ttctcttaaa
     6361 taggactcca tatctatcaa atttttaaaa acttctagta cttcttctaa aatagtatta
     6421 tccgaataaa aattggtatt ttgttctaaa tatccgattt cacaatcttt agaagtgtaa
     6481 atatctccac tatcatatcc ataaattcct gaaattattt taaataaagt ggtttttcca
     6541 gtaccattaa caccgattat accaatttta tcgccttcat ttactgtaaa actaatattt
     6601 tctaatatag aatctatacc aaaactttta tttaagttat tacatgacaa aacaatcata
     6661 aatttctacc tccttgaact atctaaaatt ataatgtttt gatataatat aatcaaggtt
     6721 atatgtatta gttttgaaaa agaaatattt tattgtgaat caaacaaaaa agaggacact
     6781 tttaggaggt gaagatgttg ggaaataaaa atatatcaat ggcagttata agaaggctac
     6841 caaaatatca tagatatctt ggagacttat tagataggga tatacaaaga atatcttcta
     6901 aagaattgag tgatataata gggtttaccg cttctcaaat aagacaagat ttaaacaact
     6961 ttggtggatt tggacaacaa gggtatggtt ataatgtaga agctcttcat actgagatag
     7021 gtaaaattct tgggttggat cgaccatata acgcagttct tgtaggagca ggtaacttag
     7081 gacaagctat agccaattat gcaggattta gaaaagctgg attcgagata aaagctttat
     7141 ttgatgcaaa tcctagaatg ataggtttaa agataagaga gtttgaagta ttagattcag
     7201 atactttaga agactttata aaaaacaata atatagatat tgctgtatta tgtataccta
     7261 aaaatggagc acaagaagtt attaatagag ttgtaaaagc tggaatcaaa ggtgtatgga
     7321 attttgcacc tttagattta gaagttccga aaggtgttat agttgaaaat gtaaacttaa
     7381 cagaaagttt atttacttta tcgtatttaa tgaaagaagg aaagtagaca acttaaacat
     7441 attaataatg agtagttgtg aagagtattg agaaagtcag aagatttaat attaaatcat
     7501 ctggcttttt gaaatattag gataaaaatt taaataatat atgtaaataa atagtattaa
     7561 ggagagtgat ttttgtggag gaattatggg aaaaagcaat tgaatttcat ggtcatgaat
     7621 gtccaggttt agctatagga tttaaagcag cacttgcagc aagagaatat ttaggatgta
     7681 aacaatcagg agatgaggaa attgtgtgta tttctgaaaa tgatgcttgt ggagtagatg
     7741 gcatacaagt tgtattaagt tgcacaatgg gtaaaggaaa tttactactt aggatgactg
     7801 gaaagtctgt atatcatttc tttaatagag aaaatgggaa atctataaga atatatgtaa
     7861 agtcaaaacc atttgagatg gatagagaag gatataagaa atatttatta gaaagtgatt
     7921 ttgaagaaat atttgagatt acagatacta agttaagact tcctgaaaaa gcaagaatat
     7981 ttaaatctct taaatgtgag gtgtgtggtg aatttgcatc tgaacaatat ataaggattg
     8041 aagaaggaaa gaaagtatgt cttgattgct ttaataaata tgaaagattt tatgaggagt
     8101 attaaaatta taaattaaaa gtattagata tgcgctaaca atattttaag atgaattagg
     8161 tagtaactat aataaaatat ataaataata ttacttgaat catacataat taaaaagagg
     8221 ctgattagta tttagaaaat aaaatcagtc tctttatgaa taacgaatta ttattctggt
     8281 tgaggtgcat ctacaggaca agctcctgca caagaaccac agtctataca agaactagca
     8341 tctataacat atgcgtcgtc tccagctgat atacagctaa cagggcattc agcctcacaa
     8401 gcaccacagc ttatacaagc gtcagtaatt ttatatgcca ttttgaaatc ctccctttta
     8461 tatgtattgt aattcaataa cattataaca aatattgttg aatataacaa ttaaattaat
     8521 tctacaacaa aaactttatt atgatattct tgttttagag ttttacaata aagtttaatc
     8581 tgcttatatt tttatttatt ttaaagagat ttattttaaa aataaaatta aatttaaaaa
     8641 gttatgtatt gattatattt gaaaatgtta tactctaaaa aagtatattt tattttaaaa
     8701 tttattaata caaaggagat ttactatgaa gaataaatta atttacatat gtatcatgag
     8761 tctacttcta tttgtagtag gatgttctaa taatccaaac aaagaaagta ctattaaaaa
     8821 agactctaag aataaccaaa gccaagttaa agaagaaaaa agagaacctg tgaaaaaaga
     8881 tataactata agtttcgctg gtgatgtaac tatgggaaac tataaaggct cgtcatatta
     8941 tggtagtttt gaccatgaat ttaaaagaca aggagaagat tataattatt ttcttaaaaa
     9001 tgtaaaacct gtatttaaaa aagacgactt aacagtggtt aatttagaag gtccacttac
     9061 tacagcgtca aatgcaaaag aaaaaaaatt tgcatttaaa ggaaagcctg gatatgtaaa
     9121 tattttaaaa tctggaagtg tagaggcagt gagtgttgca aataatcatt cagaagatta
     9181 ttttgaagaa ggaatgaaag atacacagtt tatattggat gagaataaaa taaattattt
     9241 tggattaggg aaagatgctg ttgtagatgt caaaggaatt aaagtgggtc tattagggta
     9301 taatggctta tcaactgagt ataatgaaaa aaacttaaaa caaatggaag atgatattaa
     9361 gtccttaaaa aagaaatctg atgttgttgt agtgtacttt cattggggga tagaattaga
     9421 ttattatcca gataaaaaac aaaaagattt tgctcattat gcaatagaca agggagctga
     9481 tttagttgtg gggtctcacc cacatgtgat tcaaggaata gaaaagtaca aaaataagta
     9541 tatagcttat agtttaggga atttttgttt tggagggaac aagaatcctt ctgatacaga
     9601 tagttatata tatcaacaaa cttttacttt ttcagataat aaattaactt caatcaaaga
     9661 gccacatata ataccaacat caataacatc tagtagttct agaaataatt atcaaccaaa
     9721 agtattggat ggaagtgaga aagatagagt tttgaataaa ctcgaaaaaa taagtaaaga
     9781 tttaaatcaa taaaatataa aaaaaaataa atatatatat ttattttaat aatttatatt
     9841 ctgtttagga tatgggaaat cgtggtatta aataagtaga ttttaatagt taaattatag
     9901 tcaattataa taaagctatt taatctactt ttttaatata aaaatataag ggggaatttg
     9961 taatggcttg taacacttgt aaaatgtgcg aaagtgcaga caagaaatta gaaagttttg
    10021 tagcttcaaa ggatgttgaa acagcatttc atagaacaga agatcagaaa gttaagtgtg
    10081 gttttggact tcagggggtt tgttgtagac tctgttcaaa tggaccatgt agagtaactc
    10141 ctaaatcacc aagaggtata tgtggagcag atgcagatac tatagtagca agaaactttt
    10201 taagagcagt agcatcagga gcagcttgtt atttacatgt ggtagaaaat acagctaaga
    10261 atttaaaaaa tgttggaata actaaaggtg ttattaaagg agaaaaaaca ttaaatcaat
    10321 tagcagagat gtttgggata gaaagtgatg aaaagtatga taaatgtata aaggttgcag
    10381 acaaagttat caacgatttg tataaatcga gagatgataa aatggaatta gtagaaaaaa
    10441 tagcttatgc acctagagtg aaaaagtgga aagagttagg tataatgcct ggtggtgcaa
    10501 agtcagaagt ttttgatgca atagtaaaat catcaacaaa tttaaatagt gacccagtag
    10561 acatgctagt taattgtttg aacttaggta tatcaacagg attatatggt cttacactaa
    10621 ctaatctttt aaatgatgtt atgttgggag aaccagttat aagaatggct cctgtaggat
    10681 ttaatgtaat agacccagac tacataaata taatgataac aggtcatcaa cattcaacat
    10741 ttgcaaattt ccaagataga ttaaaagatg aagatgttat aaaattagct caatctgttg
    10801 gtgcaaaagg atttaggcta gtaggatgta catgcgttgg tcaagattta caattaagag
    10861 gagaacatta tcaagaagta tttgctggac atgcaggtaa caattttaca agtgaggctg
    10921 ttttatcaac tggagcaata gatatagttc tttcagaatt taactgtact ataccagggc
    10981 ttgaaccaat agcagataaa tataaagtaa aaatggtttg tttagatgat gttgctaaaa
    11041 aagcgaatgc agaatacata ggtttagaca gaagtaaatt agatgaactt agtaacactt
    11101 taatagaaaa agcattggag tcttataagg agagaagagg aagtattgaa atagatatac
    11161 caaaagacca tggatttgaa caatctttga ctggtgtaag tgaaaagaac ttgaaagcgt
    11221 ttttaggaga ttcatggaaa cctcttatta atttaattgc agaaggaaaa attaaaggtg
    11281 ttgcagctgt tgtgggatgt tcaaatatga cagcaggagg acatgatgta aatactgttg
    11341 agcttactaa agaattgatt aaaaaagata taatagtact atctgcagga tgttctactg
    11401 gaggattaga aaatgttggt cttatgtcac ctggagcaga agaattggct ggggaaaact
    11461 taaaagaagt atgtaagact ttaggaatac caccagtatt aaactttgga ccatgtctag
    11521 ctataggaag actagaaata gtagcaacag aattagcagc tgagcttgga attgacttac
    11581 cacaattacc actagtgctt tcagctccac aatggttgga agaacaagca ttagctgatg
    11641 gagcttttgg tcttgctctt ggtttacctc ttcatttagc tttacctcca tttataacag
    11701 gaggaaaatt agtaacagaa gtattaacag aaaaattaaa ggacttaaca ggaggacatg
    11761 ttatagtgaa tccagaccct aaatcttcag ctaatcaatt agaagaaata ataatagaca
    11821 gaagaaaaaa tttagggtta aaggatgtgg aatgtaatgc atagaatttt tataaataaa
    11881 gatttatgta caggatgtaa gagctgtgta ctagcatgta tgctaaaaca caataaagat
    11941 tatgacatgt acactcttga tttagaaaat atagataatg atagtagagg gcatatagaa
    12001 ttagatagta aacataataa tccagttcca attctttgta gacactgtga tgaacctgaa
    12061 tgtgtattag catgtatgag tggtgcaatg cataaagata gtgaaagtgg aatcgtttca
    12121 tatgatgaag agaaatgtgg ttcatgttat atgtgtgtaa tgtcttgtcc atatggatta
    12181 ttaaagccag atgatagaag caagcaaaac atacttaaat gtgatttatg taaagatgag
    12241 gagtatccta gatgtgtagc taattgtcca agtggagcaa ttgaattaca gaaggaggaa
    12301 aatgatgaat tatgtagtgt taggggctag tgcggctggt ataaatgcag taaaaacatt
    12361 aagagaatta gataaagatt caaatatagt agtaatttct aaagatgaaa acatatactc
    12421 aagatgtatg ttgcatcatg ttatatctga acacagaact ttaaaacaaa taaattttgt
    12481 tgatgaagat tttatggagc aaaataatgt aaattggatt gcaggcaaga ctgttaaagg
    12541 tatagacgta aataaaaaag tagttcagac agaagacatt actgtaaatt atgataaact
    12601 tttaatagct acaggtgcat cttctgctat tcctcctata aaaaatttaa gagaaggaaa
    12661 ttttgtatat tctgtgagaa acatagatga catttataaa ataaaagaaa aagcacaaaa
    12721 ttctaaaaat gtagttataa taggtgctgg tctagttggt atagatgcac tagtgggatt
    12781 atttaaatat gagcagttga atatttctgt agcttttatg gaaaagtaca ttttagatag
    12841 acaattggat gaatatacag catcagtgta tgaaaataag ttcaaagaaa aaggtgtaaa
    12901 attttatcca agtgcatcaa tacaagaaat catattggat gacagtaaaa atgttaaagg
    12961 tgttgcattt tcaaatggag aaattttaga tgcagacatg gtaattgtag ctacaggggt
    13021 taaaccaaat gctgactttt tagatgaaac aggaatagaa tatgatagag gtataataat
    13081 agatgatatg tgtcaaacaa cacaaaaaga catatatgca gcaggagatg ttgtaggtaa
    13141 aaatgctatt tggcctctag cagtaaagca aggaattgta gctgcatata atatggctgg
    13201 aaaagataag aagatagaag atgaatttgc ttttaaaaat agtatgaatt tcatggatat
    13261 accaactatt tctataggaa tgaatacacc tgtagatgat agctataaag tattaaccag
    13321 acatggactt aatgattata aaaagtttat ttttaaagat aatgtaatct atggagcagt
    13381 tatacaagga gatatttcat atgtaggtgt attaacttat ttaataaaaa ataaagttga
    13441 aatatatgat ttagaaaaca ggatatttga tgtatgttat gcagactttt ttaagataaa
    13501 agaaaatgga gaattttgtt atagcgtata atatatatgg agtaaggttt ataaatacag
    13561 taaatcaata aatacagtaa atcaataaat agagttattc taaaataaga aaaatgagaa
    13621 atcttattta gaaatagctc tatttttgta attaagttta aattatattt aatttgtaaa
    13681 atattatttt gaacaattat acatatattc tctagttaga ggtaaatcat tttttatgcc
    13741 tttagtgaaa agtatttgat gtatatctat aataccagta ttgaaagcag cggcacaaga
    13801 acaaaggtat aaatcccaca ttcttataaa cttatcatca aacatttctt taatctttgg
    13861 aagattctca gagaagtttt tttgccagta tagtaaagtt tttacataat gtaatcttag
    13921 actttccaca tctatagtat gatacttgta atcactacaa atatgtatca tttctcttag
    13981 actaggaata actcctcctg ggaaaatata tttttttatc caagggtctc cataagattc
    14041 ctgcaaccca cttatatagt gaagtaaaaa taatccgcca tcttttaaaa cagcgtttac
    14101 gtttttaatg aaaagttcat agttttctct accaacatgt tcaagcatcc caacgcttac
    14161 aaccctatca aacataaggt ctgatttttt taattctctg tagtccataa gtcttacctc
    14221 aaggtagtct tgaaggttct cttctttgat tcttgcgtta aattccttaa attgctcttc
    14281 gctaagtgta attccaacac catgaatttt atattttttt gcagcttcta ttagtaaaaa
    14341 tccccaacca caaccaatat cgagaagact cataccttcc tctagattta gcttagttaa
    14401 tatgtggtga actttattga cttgtgcatc ataaagagta tcattatcat ttctgaagta
    14461 tgcacaagaa taactaagtg tcttatctag ccataagcta taaaaatcgt taccaatatc
    14521 atagtgggca tgtatttctt ttttctgatg tctcattgaa tttgatgagt gtaatagatg
    14581 ttttacagct gaattatcaa tattgaattt gtctatttgt tttaaaagta gatttaaagt
    14641 taagaataaa tctccctcaa cttcaatatc tctatttatg taggcttctc caagtgctaa
    14701 agatgtactt tttaatagtt cagacttgct aatatcgtta tttactataa ctttgaactg
    14761 aggggagcct tctccaatta gaaattcttc ctcatcttta agcctaacta gaaatggtgt
    14821 ttcaccaaat ctctctaaat agtcttttaa aaaatttttt gtaatattca tattaccagc
    14881 tccttctaat gtaaatccag taagtttccc tgcttaaaat atattatagt ccttttttta
    14941 aaaaagtaaa attttttcaa taaatttttt atttaaagga aatttatttt ttataaagaa
    15001 atttcatgtt gtagtatatt ttttgcctat aaattttggt actggatata atattaaact
    15061 gttaatgata taataaattt aatctataaa gtaaataaaa ttttgtaata aatagttaaa
    15121 actattttat aaggagatat aggatggaag tatatgcttt ggttgggtca agtggcacag
    15181 gaaagagctt taaagcttta gagttcgcgt atgaaaatga tatagaatat ataattgatt
    15241 aaaaaatagc tacgcacact cgtgacttta gtcatgaatt agtagctaaa atagtcagca
    15301 tatagggaaa cctatatgta gagataggat agaacctatc caatactact tgaattgctg
//
LOCUS       DBGJFK010000088        14900 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.090, whole genome shotgun sequence.
ACCESSION   DBGJFK010000088 DBGJFK010000000
VERSION     DBGJFK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.090"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(355..1758)
                     /locus_tag="ACOIAP_003168"
     CDS             complement(355..1758)
                     /locus_tag="ACOIAP_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HGZ2640043.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILVNSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKANTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGV
                     TGEADAISASPVAARDGVPIILTDGNSMGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFDTNKRVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     DNGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(2221..4116)
                     /locus_tag="ACOIAP_003169"
     CDS             complement(2221..4116)
                     /locus_tag="ACOIAP_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HGZ2640044.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAQDSDNKLTATIKSTS
                     TVEVKRAKDSTNVITLNVGDQHLDFSKVITSEDGTFEGYEKSYSDIESKELHTITVKN
                     ADLQDITAEELFDGIRLTTLGRELVNKVKNGYTLTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKLETISVSSKNHKLVRELHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIESEILRV
                     LGSNLSSKKIYIVGGESKISKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(4754..4897)
                     /gene="scfA"
                     /locus_tag="ACOIAP_003170"
     CDS             complement(4754..4897)
                     /gene="scfA"
                     /locus_tag="ACOIAP_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HGZ2640045.1"
                     /translation="MKNKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(4963..5325)
                     /locus_tag="ACOIAP_003171"
     CDS             complement(4963..5325)
                     /locus_tag="ACOIAP_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HGZ2640046.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(5383..5676)
                     /gene="yajC"
                     /locus_tag="ACOIAP_003172"
     CDS             complement(5383..5676)
                     /gene="yajC"
                     /locus_tag="ACOIAP_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGZ2640047.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLGV
                     GDKVVTIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(5810..6931)
                     /gene="tgt"
                     /locus_tag="ACOIAP_003173"
     CDS             complement(5810..6931)
                     /gene="tgt"
                     /locus_tag="ACOIAP_003173"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGZ2640048.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHNFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPADREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITSIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(7010..7495)
                     /locus_tag="ACOIAP_003174"
     CDS             complement(7010..7495)
                     /locus_tag="ACOIAP_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HGZ2640049.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKAQQNKEDEDKS
                     I"
     gene            complement(7507..8532)
                     /gene="queA"
                     /locus_tag="ACOIAP_003175"
     CDS             complement(7507..8532)
                     /gene="queA"
                     /locus_tag="ACOIAP_003175"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGZ2640050.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLMGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLSKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGNNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(8850..9869)
                     /gene="ruvB"
                     /locus_tag="ACOIAP_003176"
     CDS             complement(8850..9869)
                     /gene="ruvB"
                     /locus_tag="ACOIAP_003176"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGZ2640051.1"
                     /translation="MQGFEDENRIITSTMKVEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSNILDAKIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(9976..10578)
                     /gene="ruvA"
                     /locus_tag="ACOIAP_003177"
     CDS             complement(9976..10578)
                     /gene="ruvA"
                     /locus_tag="ACOIAP_003177"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGZ2640052.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLAESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(10571..11080)
                     /gene="ruvC"
                     /locus_tag="ACOIAP_003178"
     CDS             complement(10571..11080)
                     /gene="ruvC"
                     /locus_tag="ACOIAP_003178"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HGZ2640053.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(11392..12021)
                     /locus_tag="ACOIAP_003179"
     CDS             complement(11392..12021)
                     /locus_tag="ACOIAP_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640054.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDTGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            12224..12547
                     /locus_tag="ACOIAP_003180"
     CDS             12224..12547
                     /locus_tag="ACOIAP_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HGZ2640055.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            12811..13665
                     /locus_tag="ACOIAP_003181"
     CDS             12811..13665
                     /locus_tag="ACOIAP_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640056.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEVYFILDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKFITQETIENKLESLVENRLDTLEDRLE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(13851..14837)
                     /locus_tag="ACOIAP_003182"
     CDS             complement(13851..14837)
                     /locus_tag="ACOIAP_003182"
                     /inference="COORDINATES: protein motif:HMM:NF028352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide-binding domain containing protein"
                     /protein_id="HGZ2640057.1"
                     /translation="MPFFKEGGRFTIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSH
                     IGEWCEEKTNGKYKSSDMIYISSEELRELNIEAITEKLKMAEGFNKIIVNATDYVDVK
                     VFTIAFIRAVNSGKEFMFRSAAAITKVLGGVSDKELLTKDELVSKGNTNGGIILVGSH
                     VNKTTQQLEELKNCKYPIEFIEFNQHLVLQENGLKNEVKRVIKVVEKKISSGKTVAVY
                     TRRERFDLDTNDKDKQLMISVEISDAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALR
                     VKKATVMGQIKPGIPVWMTGKESKFPNMPYIIFPGNVGEISTLRESVEILMG"
BASE COUNT         4659 a         2639 c         1620 g         5982 t
ORIGIN      
        1 tcattttaaa tatgttcaaa atagaactta taaaagaaag gtgtctgctt cattcaaaaa
       61 aacaaattta atactactca aactattaca aattttaaat tcaatattat taaaacaatg
      121 aaaataaaaa taagaatgta tttttagaca tattatttat atctaaatac attcttattt
      181 tcagttcatt caatatatac ttatttttca attaagctcc taattttatc tactatatat
      241 gaagctattt ctctacctat tttaaacaat ctaaatgaat ttttattttt taatgatatt
      301 tttgtgattt atctgacata ttagtagtaa ttataactta caaattgttt ttatttattc
      361 tttatatctt ccataaaatt catgtgtagc atatagattc ttatctcctg ttatagctat
      421 accaaatccc attatttcat accctttatg caacatatta gtaccttctt ctggatttgt
      481 cttccactca ttaaaaataa agtttcctat atcatctgca tctctatttg tatacacagg
      541 tttatctgga attttatatt taattatatt ttcaccttga actgcaatat atccaggttt
      601 aatctcactc caatctaggt atttcaaaaa agtagaatat gaattttttc catttatcgt
      661 atgagataag gtcttcttat ttgccattaa attagaccaa tcatttgcta atccttctaa
      721 tctacttgct acagataagg ctcttactcc attatctttt ctgtactgct ttgtaagagc
      781 atatacttta ccctttattc gctctttaaa tgctctatca tttggattgt aatataagcc
      841 ttgttgattt ggtgaagctt gatttataca ttgcttgata acattctgat ttatgcctcc
      901 tagtacagtc aatttgtctg caccacttaa aatactcttg ttactgccat tttcaactaa
      961 aaccacagga gcattttttg ctattgtaga agcagccaaa gcgtctgtta attgcaaccc
     1021 tttacttaaa taaaattctt tactattttt ataaaattct tgtataaccc tcttattagt
     1081 atcaaatcta tctgttccac ctaatctaat agagtttgta ctcttaacca attcgtcact
     1141 gattatttca ctagaaccaa gtgcataact ctttaaacct gttgtgtcaa atcccatact
     1201 attcccatct gtaagtatta taggtactcc atctctagct gctactggtg atgcacttat
     1261 cgcatctgct tctcctgtaa ctccatttgc tataattact ttatctattg gcttaatttc
     1321 tttgattttt tcagctattt ttatgcttgt atcaaatcta ttttcaccaa atattctttg
     1381 tacaaccttc tttttggata gtaactgatt ctcaacattc ttacttattg ttgattctga
     1441 gcctattata tatacagtat ttgctttgtt taatctttcc atagttgtat ttggaatctg
     1501 attttgtttt gtcattaaaa taggtgcatt taaagctcca gccaaaccac ttgcacttaa
     1561 tccatctgcc aagctgttat ctgaattgac tagtattgct gtattatagt tttgcttatc
     1621 tgctattttt gctgctgtct catatctgtc attccctttt atttgctcaa ctgatgtcaa
     1681 cgcatttacc ataggagtat ttaccattac taaaaatagt gtaagtccta tagccaatat
     1741 ctttttacta ttcttcatat tattctctac ccccaatata cttttcacat tttttattag
     1801 tatttttgtt cattttgaat caaaagttac agttttgtta ccatatttta tatatgatac
     1861 catagttatc catacaactc aaacaatata cttaaagttt ttattcttca taaattcaaa
     1921 acattataac ttatttattt aattaagtaa taaattcaaa ataatatatg ttaataagac
     1981 atttaatcct tgtaaacagt atcatttata ataatttttt atagtatgaa tttcccaatg
     2041 ctataatcaa aaaataaaat aaggcatctc aatctaattt ataaatgaga taccttattc
     2101 ttattatttt gatttcatta tttatatatt ttctaatatc tacactatgt cttatacatt
     2161 gacatattgt ataaccacat attatctaag taaactttta atattcattc ttatatttta
     2221 ttagttctta gtaaataagt ttattttttc tgctattttt tcaatcgcgt ttttagctat
     2281 tccttcacct atttgtacta acttggtagc attcttaagt cttagctcaa ctacttcttc
     2341 ttgtgattta gaaagttctt ctgtagttaa tactattgga gcttttgaac tagctgcaag
     2401 tggtgctgct gtaagtgcat caactaattg tccgtttcca cctacataac catcttttgc
     2461 aacatatgct ttagttgcac ctgcgtagta cttattaatt actttagcat tagtatcttt
     2521 tctattttct ccagcaagtc tttcaacttt attatttaaa tctatatcaa ccaatttatc
     2581 ttcaacttct tttgatacag aattttctcc acctactatt tctaattctt ttccttttaa
     2641 tagtttttca gcatttgcat ctaattcgtt acctgtaact attattggag caccaaattg
     2701 agcagctcta gctgatatac tcatggcatc tgcttctcca tttccaccta ctacaaaagc
     2761 agtcttaaat gtatctttta attgttttgc tatttctaaa gaagtttcaa atctatcttc
     2821 tccagaaact ctctcaactt tgcttacacc taatttagaa agtttttctt cagtttcttt
     2881 tgatatttta gattctccac ctactatata tattttctta gaagatagat tacttccaag
     2941 tactcttaat atttcagatt ctatttctga tggtaatgaa tcttttttag ataataatat
     3001 tggtgcattt ttttgagatg caagtggtgc tgatgctaat ccatcaacta tagcatcttc
     3061 tccaactaaa attattgctt ctgcttctcc atctttgaat ctctctttac taacttctac
     3121 tgctgttgta aatcttgaat caccagataa aacttctact tttaattctt ttccgtcttt
     3181 tacatctgtc aatactttat gtaactctct aactaactta tggtttttac ttgaaacgct
     3241 tattgtttct agcttttcat ttgctttact taaaactata tcaaagcttg atttttctgg
     3301 cttatcttta tcatcactat cttcttgttc ttgagtaagg attgcttcat tttcaaatgt
     3361 taaagtatat ccatttttaa ctttattaac tagttctctt cctaatgtag ttaatctaat
     3421 tccatcaaat aattcttctg ctgttatgtc ttgtaaatct gcatttttaa ctgttattgt
     3481 atgtaattct tttgattcta tatcactata actcttttca taaccttcaa aagtaccatc
     3541 ttctgatgtt attacttttg agaaatctaa atgttggtct cctacattta atgtaataac
     3601 atttgttgaa tcttttgctc tttttacttc aactgtactt gtagatttta tagttgctgt
     3661 caacttgtta tcagaatctt gtgctaaagt tgcattgtaa gcattaactg catctactat
     3721 ttcttgagca gttttgtagt tttcaatttt atagtcaact acttttccac ctaaaacttg
     3781 atgtccttta tcttgaatag taacttttaa actttgccct tctgttaatg agtttatttt
     3841 attttgtaat tgagttgcat tagttaagtt tacattgtct acttttatat cgtaaactct
     3901 atcatttaca tttgctcctg cttttgtatc ttcaaactta acttctaatg cttttctaac
     3961 ctcttcgatt agtttagcag aatctttcgc acttactgtg taatttttat caacattttc
     4021 tgtcacagta ttatctgcga atattggtgc agctgcactc ataactgtag ctcctgccat
     4081 tactattgcc atacttcttt ttttgttgct caacatattt atgtcctccg aatattgttt
     4141 ttgatttttt atattcgtat ttctcacata taaataatat tatatataat attatttttc
     4201 aatatatttt atatgtttac ataatttact aacacaaaca atagtaatat cttcttgaac
     4261 cccttccccc acttagctgt ttatgattat atccaaagat agaaaccctt attttatagt
     4321 gattttatat tagacaatca tatactaaca aaattattca aactccactt ttatatacta
     4381 ctatgcacta atttttgctt tctcttatta cttaaatata tatcactgaa ttaatatcta
     4441 tctccatata ttaaaatgca taacatatta caaaaatcat cataaattag aatttaaaat
     4501 taaaaattat tctaatacat gtaattgata aaaaataaaa tataagagta gctattttaa
     4561 aataaatact cttatataat tagatatttt tttattagat atttttgcat aattaaacat
     4621 taagaaatca aatttaattt tatataaata gtttaaatat tttatataca aacaaaaata
     4681 aaagaggata cctcctaatg ataaaagaat cacattgaga taccctctta caaacaacta
     4741 aatcaataat tttctatctt tcacactctt gatttgcaac tgtacaagaa gttttacaag
     4801 ctgattgaca agaagtttga cactctccac atccaccttt tgcagcactt tgctttaaag
     4861 tagcttgaga taaagttttt acatgtttat ttttcatttt aaacgcctcc atttctaatt
     4921 gtttcctatt gattatatca taaaactacc ttaatataaa ctctatttaa agttgacacc
     4981 caatacgcct ccaatgcctc ctgctgctga tattagcaat aacttataaa tcattcctac
     5041 ttcgaataca aacttttctt gtgctaaaaa cacagtcaaa aaaatacata ctatgtacaa
     5101 aagtcctact aaaagcccat acataagtcc tttttctttc atgtgttttg aagtataaaa
     5161 ccctcctata gctgcagaaa tagtagttat aaatgatgaa accatagtta tattatcccc
     5221 accaatatct gtaaatgtca aaaataagtt atacactaat aaaacagcca aagttattat
     5281 atatgcatat cctagacctt taaaaatata attagatttt cccataaaaa aacctcctct
     5341 caaattaata tatattcgag aaaaggcttt taaattacta atttagtctt cttctatttc
     5401 ttctttttta gatttaacag ttcctatagc ccatttttca aatggtactt tagttctatt
     5461 tggtcctaat tctaatatta caacatcatc ttcaacttta gctacattag ctactattcc
     5521 acctattgta acgaccttgt ctcctacacc taggctactt ctcatttctt ttaattgttt
     5581 gtcttttttc ttttgaggtc taatcattag gaaataaaag attgcgatta ctactaccca
     5641 tagacctata ctcataatta tttgttgctg tggcattaat ttttcactcc tttgtaaatt
     5701 atactctttt gtaaatcata ataaatgttt atataacaat ttactttctc tatctttgag
     5761 tactattgaa tattatatat taaaatgatt ataattaata gtgcaaaatc tatatttcat
     5821 atccatattt tgcaaaaaat tcatttctaa aatcaagtaa tctatcttcc attatcgcct
     5881 gtcttatttg tttcattaaa tttaataaga agtgaaggtt gtgagtagtt attagtcttg
     5941 cacccagtat ttcatttgct tttataaggt gtcttatata agctcttgaa tagtttttac
     6001 aagcataaca atcacattca gggtcaagtg gagtaaagtc ttcagcataa gttgcatttc
     6061 taactactac tttaccttgg ctagtcattg cagttccatt tctagcgata cgagtaggta
     6121 agacgcaatc aaacatgtct actcctctta taacaccttc cactaaatca tctggactac
     6181 caactcccat taggtacctt ggtttatcct ttggcataag tggagttgta tgctccagca
     6241 catcatacat aagtggtttt ggctctccaa cactaagccc accaatagca tatcctggta
     6301 agtcaatact agttatctct tttgctgatt gctctcttaa atctttgtac atcccacctt
     6361 gtattatacc aaataaagct tgcttatctg tattattatg ggcatcttta catcttttta
     6421 accatcttgt tgttctttct aaagaatttt ttacatattc tctatctgct gggtatggtg
     6481 cacactcatc aaacgccatc attatatctg aacccaacgc attttgtatt tccatagctt
     6541 tttctggagt tagaaaatgt tttgaaccat ctaagtgtga cctaaattcc acaccttctt
     6601 cttttatctt tcttaaagga cctaagctaa acacttggaa tcctccacta tctgtaagta
     6661 ttggtttatc ccaattcata aaattatgaa gaccaccagc tctttttata agttcatgac
     6721 ctggtctcat atataaatgg tatgtgttac taagtattat ttgtgaacca atctctttta
     6781 attcttctgg tgtcatagat tttacagttg cttgagttcc aactggcatg aatattggcg
     6841 tttcaataat tccatgtgga gtgtgtaatc ttcctaacct tgcgccactc tgcttacaag
     6901 tctttatcaa ttcgtatctt actgcgtaca taaagttctc cttaatcata tttatttctc
     6961 attatttctt aagatatatt tgtaataagc tattcatata atttattgtc taaatagatt
     7021 tatcttcatc ttctttgttc tgttgcgcct taattgcttc ttcatcatga atactcatta
     7081 tattaagagc actcttgtct tttgttacta aaaacttttt tatagcaaac agccctgcaa
     7141 tagctataac tcctattaaa acatctatca taccttcatt tttaggcagt aacaacattt
     7201 ttctagctat agcgtaaagt aatgcctcaa taaatgctcc tggtatatga agagataaca
     7261 ttactacaag ttcaacacct atcactaaga gtaatatttg tgctaaaaaa tcattaagct
     7321 gactgtattg tactggattt tgaaaatcaa ctatatacgc tccccacata agtcttagaa
     7381 catctatagt tcctaaaaat actgctatta gaactactac tgctaaaaca cgttcaaata
     7441 taaaagcaat ctttaatata gggttattct ttttttgttt ttgtaaacta tgcatcaatt
     7501 acctccctac tttataatca tagcatctcc aaaactgaag aatctatatc tttcttttac
     7561 tgcctcatta tatgcattta aaacattatc ctttccacaa atagcactta ctaacattat
     7621 tagtgtagac tctggcaaat gaaaattagt aataagttta tctaaaactt taaatttata
     7681 acctgggtat ataaatattt ctgtccatcc actggtttct ttcatttttc catcctcatt
     7741 acaagctgat tctatagttc tacaactagt agtaccaaca catattacat tatttccatt
     7801 ttcttttgct ctatttattt tgtcagctgc ttcttggcta accatataat attctgaatg
     7861 catcttgtga tttaaaacat cttctacttt tactggtcta aaagtgccta aaccaacatg
     7921 tagagttaca aaagctatat ctacaccttt ttcttttatt ttacttaaca attcttctgt
     7981 aaagtgtaat cctgctgtag gtgctgctgc tgaaccatta tgctttgaat aaacagtctg
     8041 atatctttct ttttcatcta atctagcagt gatatatgga ggtagtggca tatttccaag
     8101 ttcatccaag atttcttcaa aaattccatc ataatgaaat tttataattc ttgaaccttc
     8161 atctgataaa tctacaactt ctccaattaa ctttccattt ccaaaagaaa atttagtccc
     8221 tacttttgct ctttttcctg gttttactaa agcctgccaa gtatcttcct ctgttctttt
     8281 taataataaa aactcaattt tacctccagt ttcaagtttc tctcccatca atctggctgg
     8341 tataactcta gtattattta atactaaaca atcccctgga tttaaatatt ctattatatc
     8401 tctaaatact ttatgctcaa tattgcctgt ctctttatct aataccatca atcttgaact
     8461 agctctatct tctataggaa cttgagctat aagttcctgt ggtaagtcaa atttaaaatc
     8521 acttgttttc aatgttaaac ttcctctctt aaaatttctc cagctacaat aatatcaaaa
     8581 aaataactta ttttccacaa tattaccata atctatcaag aaattgctat ttttaacaga
     8641 catcatatcc acaatatata gatatttttc cacgatatgc acgtattatc cacaatatat
     8701 agatacaata cgcacaaatt ttatcgtatt tatccacagt atctacagat ataattacca
     8761 ttttgtggat atatttgaat ttttagccat tttagaaata ttttaattta atgactattc
     8821 tattttataa atacttgcat aatctatttt tatttttcat taggatatgg aatttttaag
     8881 tgttcatatg ctaatggcat ggctaccctt cctctaggtc ctctatttat aaatcctaat
     8941 tgaagcaaat atggctcata tacatcttct attgtatttc tatcttctcc aatagaagct
     9001 gctaatgtat ccagacctac tggacctcct ctaaattttt ctattatagt cataagaagc
     9061 ttctcatcta caaaatcaag acccaaacta tcaactccta aaagttctaa agcatctttt
     9121 gccaccttat cagttatttt tccatcagct ctaacttgtg caaaatctct aactcttttt
     9181 agtaatctat ttgctatcct tggagtccct cttgaacgtt tagcaagttc taacgctcca
     9241 ttagactgta tctttgcatc taaaatattt gatgacctaa gtactatttt tgaaagctca
     9301 tcaactgtat aataatccag tttacaaata acaccaaatc tatctctaag tggatttgta
     9361 agcataccag ctcttgtagt agctccaata agtgtaaatt taggaaggtc aagtcttatg
     9421 cttcttgcag atggcccttt tcctattatt atatctaggc aaaaatcctc cattgctgga
     9481 tataaaactt cttcaacact tctattgatt ctatgtatct catctataaa taaaacatca
     9541 ttttcattta aatttgtaag tatggctgcc aaatctccag ctctttctat tgcaggtcct
     9601 gacgtaattc ttaaatttac ccccatctca ttggctatta tacttgctag tgtagttttt
     9661 ccaagacctg gtggtccata taaaagcaca tggtctaatt gctcatttct cgatttagct
     9721 gcttctataa atatactaag ttgctctttg gatttttctt gccctaaata atcttctaaa
     9781 gtttttggtc ttaaactgtt ttctatatct atatcttcca ccttcattgt agaagttatt
     9841 atcctatttt catcttcaaa accttgcatt tatacccctc ctttcgtact tttgaaaatc
     9901 tactttatat attttcaaat ttacataaac tccttaaata ttgttttaaa atctaaatat
     9961 tataaaatcc aaatattatt ttaaggattt actcattata tatgtaagtg ctttctttat
    10021 aatagcttct gtattcatac catctttttt acatttttga actgcctctt ttgattccgc
    10081 caaagtatag cctagagcta caagtgcatc tacagactca tcttgagata tcaaggtagg
    10141 tttttgtgat aataatgttg gttcaaactc tatgttattt ttatctacct tatccttaag
    10201 ttctaagaca attctttctg ctgtcttctt accaacacca ggagctttgg ataactttcc
    10261 aatatcttca cttaaaatat atgcgcctaa ttgtgctggt gatgcaaatg atagtattga
    10321 aagtgctacc ttaggtccta tttttgacac agatgtaagt agttcaaaca tcttaagttc
    10381 ttctctactt acaaaaccac aaagactcat atcatcttct cttacaatta atttagtata
    10441 tatttttgtg gcttctccca cttgtaaatt cattattgta ttggatgata catttatttt
    10501 atatcctatc ccattatttt caacaactat actgtctata taaatttctt ctactgtacc
    10561 ttttatataa ctatacatat ttaccaccta tattctttag agttttttca agtttgtttg
    10621 agtgagcatg gcaaatagcc acagctaaag catctgcaac atcatctggt tttggaactt
    10681 tttttagact taaaaatgaa gttaccatct gttgaacttg tgctttatct gctctcccat
    10741 atccaactac accttgtttt acttgaagtg gagtgtattc atatacaggc ttcccattat
    10801 gagcacatgc aagcatagta acacctctag cttgtgcaac tgttatagct gtttttacat
    10861 tcttgttaaa gaataattct tccattccaa cttcatctat attgtaattc tttactattg
    10921 tatcaattcc tttatataca agttctaatc ttctcgatat attcatatgg gcaggtgttg
    10981 taactgctcc ataatcgatt actttaaact tgctattttt gtattcaatt ataccatatc
    11041 caactatagc tatacctggg tcaatcccca atattatcat tttttaaaat tccccctaaa
    11101 aataaaagaa ataccaaaat gtatttctca taaaaactta tgttctaaat cattatatca
    11161 taaataatat taacaaatca taaaatgctc tatgtaaaat ataaaatcaa ataaaaaagt
    11221 tatatcaaag caagatttta cctcaatata acttttatat ttagtacaaa taaattattg
    11281 catttttata tgaattaaat gtgactacaa ttttaatact aatctatcta atattaaatt
    11341 atttattatt aacttactta gtatttaact tgaaatagta ttaatttact attaacttgc
    11401 aaagtcttct aatcttgaat aggcctcttc ttcagtatcc ataactacac cttttttgat
    11461 ttcatcttga actgttttag gaagtgaatc tactcttatt tttgtttttt ctactaatgt
    11521 tttacttcca gtatcatcat atttatatag tgctatattt ccattatcat tttcaatagt
    11581 atatttacct tttatagtaa catccattgc ttgtacatct ttattatcac tatatttaga
    11641 ttctaccaat atgatttcat ttttatccat actctttatt tttttagttg gatattcttt
    11701 tttaaaatat gatactattt ctgactttgt cttatctaat aatgactctg gaactattcc
    11761 tgccattgta agtgttctct tatagttggt ttcattttcg ccttcacttt gaagccaaac
    11821 ttcacaattt ttatttaatc caaaagcttc ttttgacttt tcattcatat tcgcactagt
    11881 acttacaact tcaccagttt gaactccatt gtgttttaat cttgtcccta tataaactcc
    11941 actacttaat acaaatactc caactagtat taaggcagat attttccaag gaaataattc
    12001 ttttttcttc ttttcaaaca ttgattacgc ctcctttttc tattattttc tccaagctgt
    12061 aagtttttat acaatttagg taaattttag aagaaaatat atttatattt caaattactc
    12121 taagaataga tattttctaa atggtagttt tctcttaata gttatattct tgtaattata
    12181 tggacataat ttataataaa taatcgttta ggaggtaata actttggaaa gaataaactg
    12241 taatgtaatt aactgttcac ataacaacag tcatatatgt tatgcagata aaatttttat
    12301 aaatggtgaa aaagctcaca atgacagaca tacttgttgt agttcatttt tagatgaatc
    12361 tatttatagc aatctatcta gcaatgttaa taatagaaat tgtgaggaat tagtttgtac
    12421 tgtaaaaaat tgtaaataca ataaagatgg tagtttatgt acacttgata atatattggt
    12481 tgctcctgaa actgatagag tgaaccttta tattgaaaca tgttgctcta gtttcgaatg
    12541 taaatagtca tagtataaat ataagggtgt caaatttaat taaactaaca tagtgtagag
    12601 tatctacaac tattagtttg attatacttg acacccttat tttaaataaa attttattat
    12661 tataaacatg tttataatgt tctaactgta attaaatttg ataaatttct ataaattgat
    12721 ataatcaata tgtaaattga atttagtaaa ttaatcataa aaataaaata tcgagtatat
    12781 agtgttatac taactagaaa tgaggtgctt atgagtacat tttatattca atttctttat
    12841 tttgtaattt atagttttat aggatggtgt tgtgaaacta catattgttc agttttacaa
    12901 aaacaatttg taaacagagg ttttttaaat ggtccattct gtcctatata tggatttgga
    12961 gcattagcaa tagttgctac tttgactcct tttgtacaca atattccttt gttatttttg
    13021 tttagtataa ttataactag cataatggag tattgtacga gctttatttt agaaaaaata
    13081 tttaatatga cttggtggga ttattctaaa cacaaattca atattcatgg aagagtttgt
    13141 ctggaaaact cacttatgtt tggtgtatta tcactgattg taatgcttat agtacatcct
    13201 attgtagtag attttataaa ctctatctct aaaaatgtgc tatttatatt tgctatatct
    13261 atagaagttt attttatttt agatttagta attacagtcc atacaatttt acaattaaat
    13321 ggtaagttaa aacaaatcaa tcttataatt aaggaattaa aagataagaa agaatactac
    13381 aaatttatta cacaagaaac tattgaaaac aaacttgaat ctttagttga aaatagactg
    13441 gatactttag aagataggct tgaaatactt aaggaaaaag aaaattatcg ctatgctaaa
    13501 aatcgtattg atgagctaaa aaataaactt aatactttgc tgtctaacca caaattactt
    13561 catagacgta taatcaaagc attccccaat ataagctcta ataaacatac agatatttta
    13621 aataaaatta aagaaaatat taaatcaata aaaaaagata aataatcaaa taaacacata
    13681 agttcaataa taaaaatact aatacataag attaaggttt agaatatttt ttgtaaaata
    13741 ctctaaacct taattaatat actattattt ttaatcttaa tttttaattt tagtttattt
    13801 cacttttaac tcagtaaatc tgagtgttta aacttcaata cactgatatg ctatcccatc
    13861 aatatctcaa ctgattccct aagtgtgcta atctctccca catttccagg gaaaattata
    13921 tatggcatat taggaaattt actttctttg cctgtcatcc atactggtat accaggcttt
    13981 atttgtccca ttactgtagc tttttttact cttagtgctt tagtgccaac atcactagaa
    14041 gtaattccac ctttagctat aataaagttg ggtcttacat taagcatacc aattatactg
    14101 gtaactgcat ctgatatttc tacagaaatc ataagctgtt tatctttatc attcgtatcc
    14161 aggtcaaaac gctctcgtct agtataaaca gcaacagttt taccactgct tatttttttc
    14221 tctacaactt ttataactct ttttacctca ttttttagac cattttcctg aagaactaag
    14281 tgttgattaa attcaataaa ttctattgga tatttacaat ttttaagttc ttctaactgt
    14341 tgggtagtct tatttacatg tgaaccaaca agtataattc caccattagt attacctttt
    14401 gacactaact catccttagt aagcagttcc ttatcactca ctccaccaag tacttttgtt
    14461 atggcagcag cgcttctaaa cataaattcc ttaccactat ttactgctcg tataaatgca
    14521 attgtaaata cctttacatc tacatagtcg gttgcattta caataatttt attgaatcct
    14581 tcagccattt taagtttttc tgttatggct tcaatattta gttctctaag ttcttcagaa
    14641 gaaatatata tcatatcact agatttgtac tttccatttg tcttttcttc acaccactca
    14701 cctatgtggg atgatttgta tccaaaagat ttatcctttg caaattcagt cattcctgct
    14761 ggtacaagta tttctccttc tttaacataa tgtacattat ctatagtaaa cctaccacct
    14821 tctttaaaaa atggcattat tatttcaccc tgaacctccc atgactaaag tcacagggtt
    14881 cctgcttcac agaattttgc
//
LOCUS       DBGJFK010000089        14750 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.091, whole genome shotgun sequence.
ACCESSION   DBGJFK010000089 DBGJFK010000000
VERSION     DBGJFK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.091"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..182
                     /locus_tag="ACOIAP_003183"
     CDS             <1..182
                     /locus_tag="ACOIAP_003183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640058.1"
                     /translation="FSCKLTKNLLIECYFLFLLNRQINKNAIPVPITIPMIFDIINFF
                     NIKENNKNAMHKPKT"
     gene            complement(357..572)
                     /locus_tag="ACOIAP_003184"
     CDS             complement(357..572)
                     /locus_tag="ACOIAP_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2640059.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDENE"
     gene            complement(583..1050)
                     /locus_tag="ACOIAP_003185"
     CDS             complement(583..1050)
                     /locus_tag="ACOIAP_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HGZ2640060.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALITRILYFSDYFVVILFLIFIINSTKYSPFILENVKRFKMMGCCLLVNTIIECVVG
                     YKSNTSLIMIFGDNSGGISPLMVISFIFALMCFVIAETFDKAIKIKKDNDLTI"
     gene            complement(2036..2734)
                     /locus_tag="ACOIAP_003186"
     CDS             complement(2036..2734)
                     /locus_tag="ACOIAP_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2640061.1"
                     /translation="MEKKYFKIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPQECQVLSVDLPEHGERKGEKNSFDPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPIIQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIMEDGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            2992..3549
                     /locus_tag="ACOIAP_003187"
     CDS             2992..3549
                     /locus_tag="ACOIAP_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2640062.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAENLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNNQMTKAVIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLM
                     SKEEAIKGLTDSIDTVLLGIHKKYD"
     gene            complement(3930..4403)
                     /locus_tag="ACOIAP_003188"
     CDS             complement(3930..4403)
                     /locus_tag="ACOIAP_003188"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2640063.1"
                     /translation="MFNEHLIRELKEDDIKDALELIWNVFEEFESPDYCDEGIMTFHQ
                     FIEYNSIIEKVKEKTLFFWGCFDCEKLIGVLAIRDLNHICMLFVDKNYHKRGVAKKLM
                     TIGIEYCICNKFSLTEITVNSSPYAVEVYHKLGFKDTAVEQISDGIRFTPMKLLI"
     gene            4696..5463
                     /locus_tag="ACOIAP_003189"
     CDS             4696..5463
                     /locus_tag="ACOIAP_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HGZ2640064.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKLWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPIIADNYMFINCFWISGKFKGKGYSNLLLQECVDD
                     AKLKGKYGLVVLSSSKKMPFLSDAKYLKYKRFRLADTSVPNYELLYFPFTDNTPIPCF
                     KNCVKQRKLNENGIVLYYSNQCPHTEKYALILKKIANSRGIDANLIKFETANEAQNAP
                     APFTAYSLFFNGEFVTNEVLSEKKIEKFLENEVKKFN"
     misc_binding    5682..5895
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6141..7175
                     /gene="argC"
                     /locus_tag="ACOIAP_003190"
     CDS             6141..7175
                     /gene="argC"
                     /locus_tag="ACOIAP_003190"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HGZ2640065.1"
                     /translation="MSKIKVGIIGATGYVGAELIRLLINHDKAELTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDVCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKDDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKSNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCQEKVSVVFTPNLIPVNRGILSTIYCTKADNISINDIHRKLTDYYEFKEFIEVL
                     PLDKVASLKNVRFSNKCVISLHENVDTLIICSAIDNMIKGAAGQAIQNMNIMFGIEEN
                     TGLKNIVPSF"
     gene            7216..8433
                     /gene="argJ"
                     /locus_tag="ACOIAP_003191"
     CDS             7216..8433
                     /gene="argJ"
                     /locus_tag="ACOIAP_003191"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HGZ2640066.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     KIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            8448..9308
                     /gene="argB"
                     /locus_tag="ACOIAP_003192"
     CDS             8448..9308
                     /gene="argB"
                     /locus_tag="ACOIAP_003192"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HGZ2640067.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFKEGIITGGMIPKIQGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            9338..10525
                     /locus_tag="ACOIAP_003193"
     CDS             9338..10525
                     /locus_tag="ACOIAP_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HGZ2640068.1"
                     /translation="MNNNSTISKWTEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYAGEKIINASGMDKIYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLELVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKIKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYEEIDEALEILKDILL
                     EIN"
     gene            10635..11657
                     /gene="argF"
                     /locus_tag="ACOIAP_003194"
     CDS             10635..11657
                     /gene="argF"
                     /locus_tag="ACOIAP_003194"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGZ2640069.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVADTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGGIMLTE
                     NIADVKGADVIYTDVWVSMGEEEQYETRINQLKYYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTDEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            11784..12401
                     /locus_tag="ACOIAP_003195"
     CDS             11784..12401
                     /locus_tag="ACOIAP_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HGZ2640070.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTINSFFNSAKKFDFEGM
                     NKVMENNDEKYNDILKELDTKDPNEQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMLGMSFSGQDLTDEKTIEMLVSIMKEKQKSVKETYVTK
                     TVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSINALE"
     gene            complement(12595..13293)
                     /locus_tag="ACOIAP_003196"
     CDS             complement(12595..13293)
                     /locus_tag="ACOIAP_003196"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047661 - amino-acid racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HGZ2640071.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSIPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKKSINI
                     PLLNIVEETVKKLPTLSQKVTLFSTSSTFESTIYQNGIIHNEHEFIFKDEWQIKLNNL
                     IQNIKIDKENPHNINIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(13455..14672)
                     /locus_tag="ACOIAP_003197"
     CDS             complement(13455..14672)
                     /locus_tag="ACOIAP_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HGZ2640072.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWMK
                     DLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNKSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TNFGFNTKNLTNLHPRKDIDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPEKA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
BASE COUNT         5776 a         1621 c         2285 g         5068 t
ORIGIN      
        1 atttctcttg taaacttact aaaaaccttc ttatagaatg ttattttctt tttttattaa
       61 ataggcaaat caataaaaat gcaattccag ttccaataac tattccaatg atatttgata
      121 tcattaattt ttttaatata aaagaaaata ataaaaatgc tatgcataaa cctaaaacat
      181 aacctttaaa atatgttgaa agttttcttt tcatataatc accaacttgt atagatttga
      241 cttatttaat tagagtatag cagtgttgta actccaaaga gtatctaaaa gattacaact
      301 attagataga gtaagtaaat attgtaataa aaaagagtgt ttttaaacac tcttttttat
      361 tcattttcat cttctacata ttcaagtata tcgcctggct gacaatctaa agctttgcaa
      421 atttcattta gagtagtaaa tcgaatagct tttgcttttc cagtttttaa aatcgataaa
      481 tttgcatttg taatatctat tttttctgcc aaatctttaa gtgagatttt cctttttgcc
      541 atcattacat ctagattaac tacaattgcc ataacatcac ctctatatcg tcaagtcatt
      601 atcttttttt atttttatag ctttatcaaa cgtttcagca attacaaaac acattaatgc
      661 aaatataaaa gaaataacca taagtggtga aataccacca ctattgtctc caaatatcat
      721 tataagacta gtatttgatt tataaccaac tacacattca attatagtat ttactaataa
      781 acaacatccc atcattttaa atctttttac attttcaagt ataaaagggg agtatttagt
      841 gctattaatt ataaatatca agaataagat gactacaaag tagtcagaaa aatatagtat
      901 tcttgtaatt aaagcaatta ctttgtcaga actaaaatca tataaaaaca taggtatcat
      961 acataagaat attataccag caacacctaa aagtgataat agaaaatata gaaatactga
     1021 taatatatta ctaaaaaatt ttgtaatcat aaaatttcat ctcctttata taaagtatat
     1081 tattgattat aatatataat ttattgaatt acaataataa attattgata taatatataa
     1141 aaccattata atatacgcta aagataagaa tgtataaggt ggtaaatttg tataaaaaag
     1201 aatatgagtt gtaaaatatt aaatgatatt atactaattg gaataatttt aactttatta
     1261 tatattattt taataccatt agtactgatg atgtatttta agagtggtat aagcattaca
     1321 aatacgaata tgccaactgt aatataaata atataagtag ctatatacat atgtgctgtc
     1381 ccatatattg tatcattgtt tatattaaaa agcttatgta attggtagca atcaataaat
     1441 aattttcaaa agaaatacct aaaaacttaa aaaatacata tatgtacatt tagttagatt
     1501 tgagattttt atatataatt ttgtagtgac aatattatat attgttatta tgtctattta
     1561 tatgcaatta ctataatatc agaagttata gtattatttg tttcattatc aataggattt
     1621 tttactttag ttttgtcaat tttatttaaa aaaattattg atataaaaga tgagaaggat
     1681 aaaactacat gatagatttc aaacataaga gtggatattt atataataga tattttattg
     1741 agtactgtaa tattaatatc acaatatata ttaataatgt attaaagatt taattttgta
     1801 gataactata atttattgag agtgataaat aaaaattata taatattaca gaagaaagag
     1861 agggagacaa tattatatcc ctcttttttc tatgctaatt aattattaaa aatttattaa
     1921 tactctatat acttttaatt tctttaataa taactaattt gttctttatg tagttatttt
     1981 aataatacta aaataaaatt aattaaataa catttataaa taatttaatt attttttatt
     2041 taactaaagt atttaaccat tcatataatg aatttaattc ttggggtgtg ttaaaccaat
     2101 gtttgccatc ttccataata gtaaggttgc aattaaactt ttctacaaat ttctctacaa
     2161 caccaatttc agtaagctca tcatgtttac catataatat ttttgttggt acattccatt
     2221 ggatgatagg atgttgtttt acatattgta gatattccca tgaaagagta tgcccaaatg
     2281 aagttgggat aattagttca tgtttaagct gttcttctga tacatttgcc caaagcatca
     2341 tatttgaaat aagctgttgc atatctagaa ttggagatac aaaaatacac tctcttaagt
     2401 tctctttttc aaagcttaac atactaaacc atgctccaat gctatttgca tataacgaaa
     2461 tttgattcca gtggcacttt gcatattcca taatagatac tagttctgga acaacatgcc
     2521 atgggtcaaa tgaatttttt tctcctttac gctctccatg ttcaggtaaa tcaacactta
     2581 aaacttgaca ctcctgtggg actgcaatat tagcaaaagc ttcagcctcc tctttattgc
     2641 cacattgtcc atgtatgtaa atatataatt tacttgaagg atttccccaa agaattgaag
     2701 gaactccatg aattttgaaa tatttttttt ccataaaaat ctcctctcag tttgatatat
     2761 tagtgattgt taaattaatc aaactataaa ataatgttgt aatatataat ttaatataat
     2821 actaattata ttagtattaa agctaattta attagtatta tattaaatta taattaaact
     2881 gtcaagattt tataatagta taaagaattt tataaattac aataattgac gaaactaatt
     2941 agattagtta aactaataaa gtaattaatt ttaaatgaaa gagggaaaat catgcgtgtt
     3001 agtagagaaa tagttataca agctacatca gatatagtta ataaagatgg gcttaacaag
     3061 gtttctttaa aagttattgc agaaaatcta ggaatacgta caccatcttt gtacaatcat
     3121 atagaaagtc tagatgattt attacttgaa gtagctcata aaggaatgag agagatgaat
     3181 aatcaaatga caaaggcagt tattggaaat tttggagata cagctataaa gtgtataagt
     3241 atagcatatt ttaattttat aatttctaat cctggtgttt atgaaacaat tcagtgggct
     3301 acttggcatg gaaataatga aacattagaa atctttgatg aatataaatc cttattagaa
     3361 aaacttattc tttcttgcaa tctaaataca aagaatacag gtgaagtatt aaacttaata
     3421 atgagtgtac ttcatggtta ttcgactttg caacttggga aatcacttat gagtaaagaa
     3481 gaagctataa aaggtttaac tgattctatt gatactgtat tattaggtat tcataaaaaa
     3541 tacgattaag taggtaaatc aactatttta acacatttat tgaacaaatt ttcatgaggc
     3601 atataaatta taattccatg ataaaaaatt ttaccatttg taacaaagga aaagctacag
     3661 gatagaagta tattgcaata atgtttattt tttaatggac aatcattctt acaaatagga
     3721 gatatatatg gaaacaacat aagttaagct taataattga attgatttat atattagtca
     3781 aaaaaatatc aaaaaataaa tcagagttcc atattagtaa ggcttttaag gtatgttata
     3841 aaaaaaataa aaaagatagt gctattttta aaatttaatt taaaagcaaa gtcaccataa
     3901 agcattcaag agactttgct ttttatttac tatattaaca atttcatagg tgtaaaacgt
     3961 ataccatcag aaatttgctc aactgcagta tctttaaacc ctaatttgtg atagacctca
     4021 acagcataag gtgatgaatt tacagttatt tcagttaaac taaatttatt acaaatacag
     4081 tattctatgc ctatagtcat taattttttt gcaacaccac gtttatgata gtttttatct
     4141 acaaataaca tacatatatg atttaaatct ctaatagcta agacaccaat cagtttttca
     4201 cagtcgaaac aaccccaaaa gaatagtgtt ttttctttca ctttttcaat aatagaatta
     4261 tattctataa attgatgaaa tgtcatgatt ccttcatcac aataatctgg agattcaaat
     4321 tcttcaaata cattccagat taattctaat gcatctttaa tatcatcttc ttttaattct
     4381 cttattaagt gttcattgaa cattataaac aacacctcta ttattaaaaa ttttaattat
     4441 aattataatt atatacctta aataaattta attcaatttg ttttataatt ctggaacatt
     4501 attataacat ttaatttata cattgtagtt aggtcataga atgtatttaa ttacatataa
     4561 aatttgataa ttcaaataat tttaaaataa tattatgtga aataaaaata tatatgacat
     4621 aatgttgttg tattcaaaat gttaaaataa agaatatatt taaaaattat catgtaatta
     4681 gaaaaggaga taagtatgca gattattgat ataaatataa ataatattga caatgaacat
     4741 atatgttgtt caatttctga aaaaaaagga gaaaattgtg ttttttctaa aaaactttgg
     4801 atgaaaaata attttgataa aggtctagtt tttaaacgat ttgatgtaag aggtaaagct
     4861 tttatagaat atattccagc agaaaatgca tggtgtccta ttattgcaga taattatatg
     4921 tttatcaact gtttttggat atctgggaaa tttaagggaa aaggatattc taatctattg
     4981 ctacaagagt gtgttgatga tgcaaaatta aaaggaaaat atggattagt tgtgctttcg
     5041 tctagtaaaa aaatgccttt tttatctgat gctaaatatc taaaatataa gagatttcgt
     5101 ttagcagata catcagtgcc aaattatgag ctattatatt ttccatttac tgataatact
     5161 ccaattccat gttttaaaaa ttgtgtaaaa caaagaaaat taaatgagaa tggtatagtt
     5221 ttatattata gtaatcaatg tccacataca gaaaaatatg ctcttatttt gaaaaaaatt
     5281 gcaaattcta gaggtattga tgcaaatctt ataaaatttg aaacagcaaa cgaagcacaa
     5341 aatgctcctg caccatttac tgcatacagt ctttttttta atggtgaatt tgtaactaat
     5401 gaggtacttt ctgagaaaaa gattgagaaa tttttagaaa atgaagtaaa aaaatttaac
     5461 taaaaggaga tataaatata ctattttgaa attatattat tttataattt aatgtatttt
     5521 gaaagtttct taagttgact aatgataata taaaacttat atcacaattt gaatgcaaaa
     5581 tggttaaagt taaccatata gaaaatattt ccaaaaattt ataaattata ttgacaaact
     5641 taaaaatata aactattata taaaacaata agaaaataaa ttgaaatcct gtgaaaaaga
     5701 gagtagcata aaactaattg atagagagct gggaatggtg gaagcctagt aatgaatttt
     5761 attgtgaata gagctttgga ggagattacc agaagtaata gtatggtaat tggtgggtct
     5821 cgccttaaga gattagagtg ggtaagatta tcttatcaat tagagtggta acgcgggtgt
     5881 atattcgtct cttggtcttt gaccaagagg cttttttaat tttaagtata catttgtaga
     5941 tactttttaa tttgagtttt aaagactatt ataattttgc caataagagt ggtaccgcgg
     6001 aaaatcgcct cttagtattt ataatactga gaggtttttt gttttaattg gaatatttta
     6061 atctgtgtat tatcaaatga ttatcatata ataaaaataa aattctgaga ctatttaaat
     6121 ataaaaatgg aggtaatcaa atgagtaaaa taaaagttgg tattattggt gcaactggat
     6181 atgttggggc agaactgatt agattattaa taaatcatga taaagccgaa ttgacagcaa
     6241 taggttcaaa ttcgtatgtt ggaaaagata tagttgatat atatccaagt ataggatata
     6301 aaaataacat gatatgtata gaaaatgaaa aagttataga tgtgtgtgat gttgtgttta
     6361 cagctcttcc acatggagtt agtgaaaagt ttgtaataaa agcaattaaa tcgaaaaaga
     6421 aggttataga tttaggtgct gactttagaa taaaagatga agaagtgtat agtaaatggt
     6481 atggagtatc ctttatagat aaaatcttac ataaaaaagc tgtatatgga ttaagtgaaa
     6541 tatacaaaga tgatataaaa gatgcagata taattgcaaa tcctggatgt tatccaacta
     6601 gtatttcttt accattaatg ccattgctaa gttctaaatt gataaaaagc aataatataa
     6661 taattgattc taaatcaggt cttacaggtg ctggtagaga attatcgatt agtagtcact
     6721 ttacggaggt taatgaaaat atcactgcat ataaaatagg gaaacacaga catactccag
     6781 aaatagaaca aaatttaagt gaatcctgcc aagaaaaagt aagtgtagtt tttacaccaa
     6841 atttaatacc agtaaatagg ggaatattat caactatata ttgcacaaaa gcagataata
     6901 tttctataaa tgatatacat agaaaattaa ctgactatta tgaatttaaa gaatttatag
     6961 aagttctccc attagataaa gtagcttctt taaagaatgt taggttctca aataaatgtg
     7021 taatatcatt acatgaaaat gtagatacat taataatctg ttcagccata gataatatga
     7081 ttaagggagc agcaggtcaa gctatacaaa acatgaatat aatgtttggt attgaggaaa
     7141 atacaggttt aaaaaatatt gtaccatcat tttagaaata aaaagtacta aactcatata
     7201 attaggagga taaatatgga gattataaag ggtggagtta cagtttcaga aggatttttt
     7261 gcttcaggga ttcactgtgg cttaagaaaa aataaagaaa aaagagattt agctttggtt
     7321 tattcagatg ttttatgtga tgcagcagca gtagttactc aaaataaagt aaagggaaat
     7381 cctgtttatg ttacacagga gcacattaaa aatggaaaag cacaagctat catagtaaat
     7441 agtgctaatg ctaatacctt taatggaaaa gaaggactta taaatgctta taaaatggcc
     7501 aaatttacca gtgataaatt aaagattaaa gaaagtgatg ttttggttgc atctacaggt
     7561 gttataggaa agccattaaa catagattta atagaagaaa atatggatga attagtgaat
     7621 aatctaagta aacaaggtca tattggagca agagaagcta ttatgacaac tgatattata
     7681 aaaaaagaaa tagcagtagc aataatgtat ggagataaaa aaataactat tggaggtatg
     7741 gcaaaaggtt ctggtatgat acatcctaat atggcaacaa cgttaggatt tataactaca
     7801 gatgcaaata ttgatggagt tttactaaaa gaagctttga aaattgctgt tgataaaagt
     7861 tttaatagag ttagtgtaga tggagataca agtactaatg atatggtaat gattctagca
     7921 aatggaaaag caaaaaatga tagaataaac aaaaaagatg aacattatca agtatttttg
     7981 agtgcactta catatgtttg tatagaactt gctaaacttg ttgcaaaaga tggagaagga
     8041 tgcacaaaac taattgaatg ttatataaat ggagcattaa gtgaagaaca tgcagtaaaa
     8101 ttagcaaaaa cagttatatc ttcttcatta gtaaagacag ctgtatttgg agctgatgca
     8161 aattggggta gaatattgtg tgctttaggt tatgcaggtg aagaaataga tatggaaaaa
     8221 gttgatatta tttttgagag tatgaaagga tatattgaag tatgtaaaaa tggaaatgga
     8281 ctagatttta atgaggaaaa agcaaaaaaa attcttgaag atgacgaaat aagtatatta
     8341 gtagatttaa atatgggcaa tgccagagga aatgcatggg gatgtgattt aagctatgac
     8401 tatgtaagaa taaatggaag ttatagaaat taggagggta tactttaatg attaatatag
     8461 aaaaagcaaa tacacttata gaagctttac catatataga aaaacatcag ggaaagacta
     8521 ttgtagttaa gtatggtgga agtgcaatga aaaaagatgg tctaaaggaa tctgttatgg
     8581 aagaccttgt gttaatgagt tatgttggaa tcaatatagt tttagtacat ggtggagggg
     8641 cagaaatcaa taagatgtta gcaaaagtgg atatagaaag taaatttgta aatggtctta
     8701 gatatacaga tgaagagaca atggaaattg taaaaatggt acttgctgga aaggttaata
     8761 aagatctagt aaataaaata catacaaaag gtggaaaagc agtagggctt tgtggaatag
     8821 ataataatat gattttatgt gacccatata aaaactatga acttggattt gtaggagaaa
     8881 tcaaaaaagt aaatgttgag cttatagaat cttgtctaaa gtcaggttat atttcagtaa
     8941 ttgcaactat aggtgttgga gatgatggag aaacttataa tataaatggt gacacagcag
     9001 cttctgctat agctaaagag ttaaatgcag ataaattgat acttcttaca gatgtacctg
     9061 gcttgttaag agagccagat gaagaaaaat cattaataac agaagttata ttagaggatg
     9121 tcgataaatt atttaaagaa ggtataatta ctggaggtat gatacctaaa atacagggat
     9181 gtgtagatgc cttaaataac ggagtaaata gggtacatat tttggatgga agagttcccc
     9241 attctataat aacagagcta tttactgata gtggaatagg tacattaata agaaaagaaa
     9301 atgaataaaa ttataagttt aagaagggag aataagaatg aataataaca gtacaatttc
     9361 aaaatggact gaatatttta tagatacata taaccaacct aattttgtta tagattatgg
     9421 ggaaggaagt tgtttttttg atactaatgg caataaatat atagatttta caagtggata
     9481 tggagtatct tctcttgggt atagtaacag taatttaaag aatgctctaa aagagcaagt
     9541 agataaatta ttacatactt caaatttata ttttaatgag ccagtgctgt atgcagggga
     9601 gaaaataatt aatgcaagtg gaatggataa aatatatttt tgtaattctg gaacagaagc
     9661 aaatgaaaca gcattcaaaa tagcaagaaa gtatagtagt gataaatatg gtaatggtag
     9721 aggaactatt ataagtttaa aagactcttt tcatggtaga acgatgatgt ctttaatggc
     9781 aactggtatg gataaatacc ataagtactt ttatccactt cccgaaggtt ttaaatatat
     9841 agaaagaaat aatattgaag atttaaaaaa taatcttgat tcgacagttt gtgcaataat
     9901 tcttgaagcg attcaaggtg aaggaggagt taatgttctt gaaaaagatt atgttttgga
     9961 actagtaaaa atatgtcaag aaaaggatat tgtagtgatt tttgatgaag tacaatgtgg
    10021 tataggaaga actggcaaac tttttggata tgaatatttt gatgtaaaac cagatatagt
    10081 tactgtagct aaagggctgg gagcagggat accagtagga ggagtattgg taaataaaaa
    10141 actttcaaaa gtactaggaa aaggagacca aggtacaact tttggaggta atctattagc
    10201 tatggtggca gcttcagttg tattagatga gatatctaag gatggttttt ataatgaagt
    10261 attagaaaaa ggaaattata taagaaaatc tattgaaagt tttaataata aagttgtatt
    10321 aaagataaaa ggtattggtc taatgatagg aattgaaact aatattgaat ctagtattat
    10381 agaagagaaa gctagaaaaa aaggattgct tattttgact gctggaaaaa atgtattgag
    10441 atttttacca ccattaacaa tcagttatga agaaatagat gaggctcttg aaatcctaaa
    10501 agatatatta ctagaaatta actaaatatt caaaaaatag tttgattaaa gataaaaatt
    10561 agaagtaaat aaaaaagtaa agtgctaaca agtttaattg aatttaaaaa gtttataaaa
    10621 aggggcgaat taatatgaat aatataagtt taaaagggaa gagttttttg acattaaagg
    10681 attttacaaa agaagagatt agatatttat taactttatc aagttattta aaaactaaga
    10741 aaaaagttgg tataaaaggc gatttgctac aaggaaaaaa tatagcttta ttatttgaga
    10801 aaacatcaac aagaactaga tgttcatttg aagtagcagc tcatgatgaa ggagcacatg
    10861 taacttatct aggtccaaat gattgtcata tgggtaaaaa agagtctgta gcagatacag
    10921 caaaagttct aggaagattc tatgatggga tagaatttag aggctttaaa caagaaacag
    10981 ttgaaagcct agcaaaatat tctggtgtac ctgtttggaa tggacttacg gatgaatatc
    11041 atccaacaca aatacttgca gactttttaa cagtaattga aaatgtagat aaagatttga
    11101 ataaagttaa atttgtatat gttggtgatg ctagaaataa tatgggaaac tcactgatga
    11161 taggatgtgc taaaatggga atccatttcg tagcactagc acctaaggag ctttggccaa
    11221 atgaagagtt ggttaaggaa atgaaggaaa tagccaagaa atctaaggga ggcataatgt
    11281 tgactgaaaa tattgctgat gttaaaggtg cagatgttat atatacagat gtatgggttt
    11341 ctatgggaga agaggagcaa tatgaaacaa gaataaatca acttaagtat tatcaagtaa
    11401 atatggatat gataaagaaa actgaaaatg aaaatgttat atttttacac tgtcttccag
    11461 catttcatga tttagaaact aaggttgctc aggagattta tgaaaagttt ggattatcag
    11521 aattagaggt tacagacgag gtatttaatt cgaaatattc aaaggtattt gaagaagctg
    11581 aaaatagaat gcatacaata aaagctgtta tggtttctac tatgactgat gtaaatatga
    11641 acaataattt aatatagata ttccttaatt tagattttgt tttaataaaa atttataaaa
    11701 tattttaaat atattattca aaaactatca ttatatgtta aaatagctta tgtatcaaca
    11761 aattaagagg gaggatttga gatatgaaaa aaatcatatt agctttaaca acttttttat
    11821 tagcaatatc tttaacagca tgttcaagtg caaaaccaga agatacaatc aatagttttt
    11881 ttaacagtgc aaagaagttt gactttgaag gcatgaataa ggtaatggaa aataatgatg
    11941 aaaaatataa tgatatatta aaggaattag atacgaaaga cccaaatgaa caatatgttt
    12001 tagattatct aaaacagaat gcgtctaaaa tcacatatac aataaaagac agtgaagtta
    12061 aaggtgataa ggctacaatc aaagtagaat gtaaatttat agattcaaca ccgttgcttc
    12121 aagaaatagt agctgaggca tttacaaaga tgcttggtat gagtttttca ggacaagact
    12181 taactgatga gaaaacaatt gaaatgttag tatcaattat gaaagaaaaa caaaaaagtg
    12241 ttaaagaaac ttatgtgaca aaaactgtag agtttgaatg ttctaaaaag gataataaat
    12301 ggataataag ttcagtaaat gatgcagtag ctgatgtatt gttatctaat cttgttacag
    12361 caggacaaga attttctaac tctataaatg cacttgaata atattgttta ggtgtagtaa
    12421 agtaataaac atatatttat ttatgaagga taccattttt ggtatccttt ttattaatat
    12481 aatgaaatac atggttaatt tctatattgt caagaaacta tgatatatgt tataagtcta
    12541 tactatttaa gataaactta taacatatat tttttataat atagtgcatg aaatttattt
    12601 aactaatttt agatatttat tgacaactga ttcagccaag cattttgatg aatcaacaat
    12661 atttattgaa ggatatgatt tttctaaaac tacatttaaa tcagtacaag caattactat
    12721 attttctata gattcatttt taacatcttc gataagttta ttccaaatat taatattgtg
    12781 tggattttct ttatctattt ttatattttg aataagattg tttaatttta tttgccattc
    12841 atctttaaat ataaattcat gttcattatg tattatacca ttctggtaaa ttgtagactc
    12901 aaaagttgaa ctagtcgaaa aaagagttac tttttgtgag agagtaggta attttttaac
    12961 tgtttcttct acaatattta atagtggtat attaatagac ttttttaatt ctttaaagta
    13021 tatatgtgct gaattgcatg gcattgcaat aaaatttaca ccagttgact caagtttttg
    13081 taatccatca attatagttt ctttcataag ttcatgattt attggacggt caatataaaa
    13141 tggggtaggt attgaatata tcatcatctt tggaaattca tcatcatatt ttgctccata
    13201 ttgagattga cactcatcaa taattaaatc aacaaaaggg gctgttgacc ttggacccat
    13261 tccagccaaa ataccaatta atttttcatt cataaaaagt atctccttta tacataaata
    13321 tatttatgta taaaataaaa atttataaaa acataaaatt atattttata atagattata
    13381 ttatacactt gtataatata agtataaagt gagtttttag attatatatt ttaatatact
    13441 ttcttatata aaaattattt taaatcaaga ttatctagta tttttaaaaa aatttttaca
    13501 gcggtatcca aatcatctac agaaacactt tcattaggat tatgacttac gcccccagcg
    13561 catcttataa ataccatacc aatatcagtt atattatcca tttcctgagc atcatgacca
    13621 gcaccactat aaatataaaa aggattaaga tttaaatcta taaaactttt ttctatgatt
    13681 tttgttattt tattagaaca tggtacagga acattttcaa aagcaagttc acttgtatag
    13741 ttaagttttc tattttcaca tatatgtgat atttcattaa atatcttttc tacagaatta
    13801 tcaagaattt cttgagaaca agagcgtaca tcaagagtaa attcagcttt ttcaggtacc
    13861 acatttgatg aagatggata aaaattcatc tttcctacag tagcaaccaa atcagcagtt
    13921 gtcttagcta ctttttcgat agctaagaca cattcacagg cacaacatcc agcatcaagt
    13981 ctcatgttca ttgggagtgt accagcatgt ccagatttac catttactga tatcttaaaa
    14041 cttttgaatc ctgtaatact tgatacaatt ccagcaggaa gagattcatt ttctaagaca
    14101 ggtccttgct cgatatgaaa ttctaaatat gcatctatat cttttctagg atgcaaattt
    14161 gttaagtttt ttgtattaaa tccaaaattt gttacagctt cttcaagtgt aattccattt
    14221 tcatcaacag atttaagaag ttcctcttta aaagtaccag caaaaacttt acttcccatt
    14281 aaagaagttt caaatctagt tccttcttct tcagcgaaag caattagttt aatattgaaa
    14341 ggataagact tattattgtg ttttgcttct tcaagaccaa ctagaggcac tattatgcct
    14401 aacataccat caaatatacc tccacacttt acactatctt gatgagatgc aactactaat
    14461 gtgggagcat ttggaaagct tgatttatat gtacctataa catttccaat gtcatcaatt
    14521 tcaatatcaa gatttaaatc tttcatccat gaactgatta aatcaataga ttttttatgt
    14581 tcttgagtca agataagtct tgtaagacca tttgttgttg aacttatttt tcctaatgtt
    14641 tgtagataat ccatacattt ttttcctaac atatttacct cctaaaaata taatttttat
    14701 ttaagctaag attagctttt atacttataa tttttgaact ttcaaataat
//
LOCUS       DBGJFK010000090        14748 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.092, whole genome shotgun sequence.
ACCESSION   DBGJFK010000090 DBGJFK010000000
VERSION     DBGJFK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14748
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.092"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(175..2841)
                     /locus_tag="ACOIAP_003198"
     CDS             complement(175..2841)
                     /locus_tag="ACOIAP_003198"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGZ2640073.1"
                     /translation="MENTNLSKTYNPKEFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPEKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDTNAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     misc_binding    complement(2916..3178)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3480..4307)
                     /locus_tag="ACOIAP_003199"
     CDS             complement(3480..4307)
                     /locus_tag="ACOIAP_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2640074.1"
                     /translation="MKIKDNKTVFHVFVRIFLVAVLILTGTLLEEKINNVPVENISSK
                     GESTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYDKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENISPKNFWQENL"
     gene            complement(4355..5791)
                     /locus_tag="ACOIAP_003200"
     CDS             complement(4355..5791)
                     /locus_tag="ACOIAP_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-Fe] hydrogenase large subunit C-terminal
                     domain-containing protein"
                     /protein_id="HGZ2640075.1"
                     /translation="MNTKNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDDLNNYFSGKFDKDTMVNLIRVTMGLDVTGDTDKNLKDSLHEAVNLDEVKRPIIS
                     IISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFIGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIDATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNRKENKYKK"
     gene            complement(5878..6747)
                     /locus_tag="ACOIAP_003201"
     CDS             complement(5878..6747)
                     /locus_tag="ACOIAP_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGZ2640076.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKIMRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(6905..7558)
                     /gene="phoU"
                     /locus_tag="ACOIAP_003202"
     CDS             complement(6905..7558)
                     /gene="phoU"
                     /locus_tag="ACOIAP_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGZ2640077.1"
                     /translation="MVNNSLDISIDTLKEQTVLMIEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEIDKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIDGKMVEIG"
     gene            complement(7586..8350)
                     /gene="pstB"
                     /locus_tag="ACOIAP_003203"
     CDS             complement(7586..8350)
                     /gene="pstB"
                     /locus_tag="ACOIAP_003203"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGZ2640078.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGSISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRIHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTIFTTPVDKRTEDYITGRFG"
     gene            complement(8369..9193)
                     /gene="pstA"
                     /locus_tag="ACOIAP_003204"
     CDS             complement(8369..9193)
                     /gene="pstA"
                     /locus_tag="ACOIAP_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGZ2640079.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGKMNFNFL
                     FSNYSASGDGGILPMIITTLYTVLVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSIGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(9195..10112)
                     /gene="pstC"
                     /locus_tag="ACOIAP_003205"
     CDS             complement(9195..10112)
                     /gene="pstC"
                     /locus_tag="ACOIAP_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGZ2640080.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKLAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGANWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPMIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(11059..11739)
                     /locus_tag="ACOIAP_003206"
     CDS             complement(11059..11739)
                     /locus_tag="ACOIAP_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640081.1"
                     /translation="MQTKILIIDGDKDNCQKLKKFMEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYITYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(11789..13804)
                     /locus_tag="ACOIAP_003207"
     CDS             complement(11789..13804)
                     /locus_tag="ACOIAP_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2640082.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTHKSIRASNG
                     ILNIDNETFTKSKLVFLIDDWEFYNHKIFKPNDFIEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNDGKNRLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NLVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRVLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCIFFAIHVSYPFVHLLGLPLVNFTYAVEDSSY
                     FIAVLCIICINGSISKIEENKLYRFLILPLGITMSIMSIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAITSNRFEP
                     IFTGWQTEYCGFIIVILFSVMMINKNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLI
                     RAFENLIYNALTFTPFDGKIILSMDEEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNNPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(13876..14553)
                     /locus_tag="ACOIAP_003208"
     CDS             complement(13876..14553)
                     /locus_tag="ACOIAP_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640083.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
BASE COUNT         4699 a         2672 c         1502 g         5875 t
ORIGIN      
        1 atcaaatttt tattgcttat aaattttaag atataaaatt catatattca taacagaaaa
       61 taaaaatata acacatctgt aaagaattat aacatcatat ttgtatatat ataaagaaaa
      121 acatacaaaa agtatagaat atatactttt tgtatgtttt atttcttctt atatttattt
      181 tattttagat tctaaatttg ttaatctttc ctcaacagat ttaatcatct cttcaaactt
      241 ttcttttttt gctttttctt cttcaattaa actttcagga gcttttgcta agaaaccttg
      301 atttgcaagc tttccattaa ctctctttat ttctccttct aactttttct tttctttaga
      361 taatctctca atttcttttt caaaatcaac taattcatta agaggtataa atatttcaac
      421 tccatcaata actactccaa ctgcatcttc tggaacatta gatttatctt ttgctatctc
      481 tacatttgaa gcagatgcta aagttataaa ataatctttg ccaagctcaa tagcttctat
      541 tttttcttca cttgggatta ttatcaattt agctttttta gaaggtggta cattcatttc
      601 tgctctcaca tttcttatac ttcttatacc ttccatcaat aagttcatca tatcttcttc
      661 ttcagccatg ttatcttctt cattatattt tggccattca gatactatta tacatccttc
      721 aacagtagga agatgagtat atatttcctc tgttataaat ggcatatatg ggtgtaataa
      781 ttttaatatc ttttcaagaa cataagttaa tgtatataat gctgcagatt tagcgtttgt
      841 atcttccccg tacaatctag gtttaaccat ttcgatatac caatcacagt attctgacca
      901 agtaaaatcg tatatctttt gaagtgctat tcctaagtca aacttatcca tgttattagt
      961 tgcttctttt acaatattat ttgctcttga tattatccat ttatcagcta gagttaagtc
     1021 ctctttaaca ctttctctag tcatgttttt aattatatct tcatcaatat tcataaatac
     1081 aaatcttgat gcattccaca acttattcgc aaagtttcta gcaaattcta ctctttccat
     1141 atagaatctc atatcatttc ctggggaatt tccagttgtt aatgtaaatc ttagtgcatc
     1201 agctccatat tgctcgatta tctccaatgg gtcgatacca tttcctaaag atttactcat
     1261 ttttctaccc tgagaatctc ttactaatcc atgaaccaaa acatggtcaa atggcttttc
     1321 attcatacag aacatacctg caaatgccat tctaactacc cagaagaata ttatatcgta
     1381 tcctgtaaca agtacacttg ttggataata ataatctaaa gcttcagtct tatttggcca
     1441 ccctagagta gagaaaggcc ataatgcaga actgaaccaa gtatctagtg catcttcatc
     1501 ctgtttaaaa tgagtgcttc cacatttagg acacttatct ggcatttttc tagcaactac
     1561 aatttctcca cactcttgac aataataagc tggtatttga tgaccccacc ataattgtct
     1621 tgatatacac caatctctta tattttctag ccattgtaaa taagttttat caaatttttc
     1681 tggaacaaat tctaattctc cttttttaag aatatctata gctggttttg caagttcttc
     1741 catcttaaca aaccattgct ctgataatct aggctcaact actgtatggc atctataaca
     1801 agttcctaca ttatgattat gctcttttat cttaattaga taaccttgtt cttttaagtc
     1861 tgctacgata gcttttctac actcaaatct gtccatacct tcatattttc cacaaacttc
     1921 attcatagtt ccatcttcat tcatagtatt taactgctca agattatgtc ttagtcctac
     1981 ttcaaaatca ttagggtcat gtgctggagt catcttaact gcaccagttc caaactctaa
     2041 atcaacataa ctatctgcaa ctattggaag ttctcttcct accaatggaa gtattgctgt
     2101 ttttcctatt aaatgtttat atctatcatc ctctggattt actgctatac cagtatcacc
     2161 tatcattgtc tcaggtctag ttgtagctat ttctaagaag tcttcactat cttttagtgg
     2221 atactttata tgataaaaat ttccgtcatg ttcttcatgt tcaacttctg catctgataa
     2281 agtagtttta caatctggac accagtttat tattctgttt cctctgtata tgtgaccttt
     2341 ttcatatagg cttacaaaaa attctataac tgcttcatta cacccttcat ccatagtaaa
     2401 tctttcttta tcccaatcgc aagaatcacc taattgttta agctggttag atatttttcc
     2461 tccaaattca tctttccact cccaggctct ctttaaaaat tcttctctac ctatttcata
     2521 ctttgtctta ccttcttgtt tttttattct ttcaacaact ttaacttctg ttgctataga
     2581 agcatggtca gttcctggaa gccaaaaagc ttcatatcca tccatacgtt tccatctaat
     2641 taatatatct tgaagtgtat ggtcaagagc gtgtcccata tgcaattgcc ctgttatatt
     2701 tggtggtggc atcattattg taaatggttt tttatctgga tttggtttag atttaaaata
     2761 cccttcatcc atccattttt tatatagcct agcctcaaat tcttttgggt tataagtttt
     2821 tgataaattc gtattttcca ttgtcctgcc tcctgtattt tataaataaa tttttaaata
     2881 tctttagaaa taaaaaagag ctcttcatcc tcttcaaaaa ggacgaaaag ctcgcgttac
     2941 caccttaatt ccaaagctta aaatacatta acgtataatt aaattatttg ttaatattat
     3001 tttataaact ttgactctca aagaatttaa cggttctaac cgtctaaact tactcatagt
     3061 tcagtttaga aactccaaag ctacattcag taaatcttat acttagaaaa tcttacagcc
     3121 agtgaatttt cctctctttt agtagtattt acttactcct cttcttctca gtctttaata
     3181 ttacatatta ttatatacaa atattattct ctttgtcaat tatttttatt ttattttttc
     3241 tgaattttct taattatatt tattttcttt tatactaatt gttatatttt aaaatatatt
     3301 tttgaagtta ttttgtctta taatgtcaat aattgcaaga ttgttttatt ttaattttaa
     3361 tactttctca ttaactttat attatattat ccttaaagta tacctctttt ttgtattttt
     3421 tatattatat gttttacttt ataaataatt tactttattt tttaccatat ttaaatttat
     3481 tataagtttt cttgccagaa atttttaggt gatatatttt ctgtaattgg caatattgta
     3541 tatcctctct cttttaagat tcttataata ttatttaaag catttaaact ttgctctttc
     3601 tcatgaatta atactactaa ttcatctctt tttcttccat aatataatat attacttact
     3661 atctgacttg tagaagactt ccaatcctgt gtatccaaat tccagtccca aattaaataa
     3721 tcatttgcca taagtttatc atatgaacct tctggcatat atggtttgct tccatatggt
     3781 aatcttatta attttgaact ttgaccagtt atttcttgta gagtattatt gcatgtatta
     3841 aattccccaa ctgttacttc tgggctttta tataacttat gtatatcatg acttacacta
     3901 tgaaaaccta ttgaattttc ctcttccaaa actcttctta cttcttcctt gtgatttttc
     3961 atattttgat taagcatgaa aaatgtcgct ttgacatcat tttcttttaa aatatcaagc
     4021 agtgcatttg tatattttga tggaccatca tctattgtta tgtatgctac tttctcagaa
     4081 gtagctcctg gaccttttgt ttcttcttga gatgctttat atatgatttc tcctaaagta
     4141 ttactttgag aaagtaattc cagtgtactt tcaccttttg aacttatatt ttcaactgga
     4201 acattattaa ttttttcctc caataatgtt ccagttaaaa ttaaaacagc tacaagaaat
     4261 attcttacaa atacatgaaa aacagtctta ttatctttaa ttttcatccc ccatatctcc
     4321 cttttataaa agcataagtt taagacttaa aaagttattt tttatattta ttctctttcc
     4381 tattactttt tatatctcta ctaaatattt ttttaacctt ttcttcttct ttttctccta
     4441 gagattccac tcttttgatt cccaaagaag ttaaaaattg taatacattt aaattatcaa
     4501 atggagtttc catattcgta ctttcactat attcatcaac attcttagta ccttcttcca
     4561 cacttaaaat acgcttagga cctcctacac agcctcctac acaccccatt ccttctataa
     4621 atgtagcgtc tatttcttta tttagaactt tctttagacc gtccatgcac tcttttgttc
     4681 cttcaaatgc tttttcttca aattttatat ttttgtcaat tcttctaact gataacttaa
     4741 ctgctttact tacacctcct gttctagcat aaactctacc tgaaagggat gcctctactc
     4801 tattactctc atccattatt gctggattta actctaatgc atcaaatatt tcttgtaact
     4861 ctttaaatgt aagcacaaaa tcaactgcat cttttatgtc ttctaacatt gcttctttct
     4921 tttttgccat acaaggacct atgaatacaa ctttagcatc tggattcaaa atttttacag
     4981 ctctcccaca agcaatcata ggagaaacgg atggtgatac attctccaat atctgaggaa
     5041 agctattttg tatcaaacta acccaaatag gacagcaaca actagttata aagcatcctt
     5101 cttcgtcctt tttcatatgt tcataataat catatgcttc ttttgcagta agcatatctg
     5161 ctgccaaagc aacttctatc atatcttcaa atcctatctt ctttaatgca gttcttaatt
     5221 taccagggct tacatctttc ccaaactgtc ctataaaagc tggtgcaact attgcatata
     5281 cagggctctt tatatctttt aacaatttta tcattggtat aaattctatt ttatctgaaa
     5341 ttgcacccaa cttacatctt gatacacaat caccacaagc actacataca tcttcctcat
     5401 tacaattaat atgcttactt cttatcttac atgactcatc ttccttatta ttttcatcac
     5461 aatatttgca agcatctgat attatggata ttattggtct tttgacttca tctaaattta
     5521 cagcttcatg tagtgaatct tttaaatttt tatctgtatc tcctgtcaca tccaatccca
     5581 tagttactct aattaaattt accatagtat ctttatcgaa ttttccacta aaataattat
     5641 ttaaatcatc ttttaaatct tcatttaaaa ttttattagg taagttttca atatcctcta
     5701 tatcatcatt ccacactgct tttacaagtt cgccaaaaag cttcatttta tatatttcta
     5761 atattttaga attatcattt ttagtattca taaaaaatag tacctccata aattaaactt
     5821 atatatgttt aatatttaca aagatactat tttttattta ttatttatct actattatta
     5881 atatgattta tttaactttc tcagcaattc tatttcaatc attattttca ttagatgata
     5941 gttgaataca ggactttttt cttcatctat attccagtct agcttatcta cattatatgt
     6001 tttcttaagg tatttatatg tatgctcttt caaataaagc ttattttcaa gtaactctat
     6061 agactgcata tgaaaatgta tttctctaca tatccttaag gcgttctcaa ttttttctat
     6121 attagtttca ctcaaactat aatccaactc atcaataagt tttgaatata tttcttctag
     6181 tttttctact tcttcttcaa acttctctac atttaaattt tcttttctca taattttatc
     6241 ttcaataagc aacatcgaaa gttcttctat ctttttaaat tcatctatga cgctatttag
     6301 ataatttggt ctagcaacat aataattaac aagaacccca aacaaaacac ccacagatgt
     6361 atctaacacc ctatgtaaag aataatacac agggtcacta tttcctacac ctaaatgtat
     6421 agccagaaag gttacacagg caactactac tgactttatt ttaaacagat tgcataaata
     6481 tattgagcac attactccta gaccacataa aaaagggtct ccagctttaa tgatggcaaa
     6541 tatgaatcct attataccac ctaaaatagt accttccact ctattgattc ctgtctttaa
     6601 agaacctttt accgtatctt gaacagaaat tatacatgca actaaagaat aaaacatatt
     6661 ctctactaga tagtcaccaa gaatcataca taaagtgaca ctaattcctg tttttatagt
     6721 cctcataccc atcttttgaa gtttcaaaat tccacctcct aaaaagcacc ttatataaaa
     6781 tacgcatcct catatttaat atgttcctag tatatcacaa ttttttaaat ttacccatta
     6841 atcatatttt tttatcaatt ctttcttaat ttagacaaaa aaaaactgct ttaaagcagt
     6901 ttttttatcc tatctcaacc attttaccat caattgcaaa aattatcttc tcgcatacat
     6961 ttgttatatg gtctccaatt ctttcaaggt atcttcctat aagtagaagt tttacccctt
     7021 ggtctatagt atttgaattt tcatgcatta tttttaaaca atcaatttgt acttgttcat
     7081 acaatccatc tacaatatca tctttagttc caacatcata agctatactt gcatcaaata
     7141 agattaaagc ttctctagtc tgagacatca tagacttaca ttcttttgcc atcttaggaa
     7201 tatctatcag ctcttttata taagcctctc cacctatctt caacatttct ctagctatat
     7261 ttgctgcata atctcctatt ctttctaact ctatcgatat attacctaat gaataaataa
     7321 atcttaagtc ccttgccatt ggttgcttta atactattaa ttctatactc ttatctctta
     7381 tttcttctct taatttatct atttcttcat catcttctac tacttttctt gcaccctcta
     7441 aatccttctc tatcatacaa gtcacagact tttctattgc ttcttcacat ttttctatca
     7501 taagtactgt ttgttctttt aaagtatcaa tacttatatc taaactatta ttgaccattg
     7561 tctaactcct ttatagttat atattttaac caaatctacc tgttatatag tcttctgttc
     7621 ttttatctac aggagtggta aatatagttt ttgtatcgct aaattctata acctctccat
     7681 ttaggaaaaa agctgtttca tctgatatac gagcagcttg ttgcatatta tgtgtaacta
     7741 tgactattgt gtagtctttt tttaaatcct ctataagttc ttctactttt aaggttgaaa
     7801 ttgggtctaa agcagatgta ggttcatcca taagaataac ttctggtctc atagcaattg
     7861 ctcttgctat acatatacgt tgttgttgac caccagaaag tcctaatgca gatgatttaa
     7921 gcctgtcttt aacctcatcc caaatagctg caccttttaa gctttcttct acaatcttat
     7981 ctaattgctt cttatctctt agcccatgta tacgaggacc atatgccaca ttatcatata
     8041 tactcatagg aaatggattt ggcttttgaa ataccattcc tactttagta cgaagattta
     8101 taacatcatc tgaagtatat atatcctctc catcaacaga aatacttcct ttaattgtta
     8161 catcttcgat tagatcattc attctattta aagttcttat aaaagttgat tttccgcatc
     8221 cagatgggcc tattaaagca gtaaccttat tctcttttat atccatattt attttcttta
     8281 atgcttgctt atcaccataa aataaatcca aatcttttac actcattttt atcttatcga
     8341 ttaattccat tattcacacc tcttaaattt aataattagc cttatttaat ttcttagcaa
     8401 cgaatcttgc caacatgttt agtgctaata caattactat taaaacaatt cctatactgg
     8461 ctgctgttgc tatatctcca ctctctttag tcagtaagta tgagtgtaca gttaatgttc
     8521 ttgcactatc aaatattcca cctggcatct tagctacagt accggctgta agtaatattg
     8581 cagctgattc tccaattata cgaccaattg ataagattac tccagataag attcctggta
     8641 ttgcacttgg aagtactacc ttatataaag tttgaaattt tgtagctcct aatgctaatg
     8701 atgattctct ataagcttga ggaactgttt ttaaagcttc ttctgttgta cgaattatta
     8761 ctggtaatat tattattgct actgtaagtg aacctgcaac tatggaatat cccattttta
     8821 atgtaactac aaagaaaatt cctccaaata atccatatac tatagatggt atccctgata
     8881 aactttcagt tgcaaatctt atagctgtaa ctgcttttcc ttttttagca tattcttgta
     8941 aatatatagc agccaatatt cctataggag ttgctacaac tatagaaact aatactgtat
     9001 acaatgttgt aattatcatt ggaagtatac caccatcacc tgatgctgaa taattgctaa
     9061 ataagaaatt aaaattcatt tttccaattc cctttataaa tataaatccc actataacta
     9121 ctaatgatac tattgtaaat agtgctgata gatatactaa tgacttcaat agattctctt
     9181 tgaactttct catcttaatt taccgcctta tttgaaagtt tatttaaaac taaatttaaa
     9241 attaatataa atgtaaacaa tactactcca gttgcaaata gcatttcttg atgtgtacca
     9301 aatgcgtaac ccatttcaag tgctatatta gttgtaagtg gtcttacact atctgttatt
     9361 gcagttggca taactggtga atttcctgca acaagtatta ccgccattgt ttctcctaaa
     9421 gctcttccta ctcctaacac tactgcagct aatactccag attttgcagc aggtaataca
     9481 actttgaata ttgtttctat ttttgatgca ccaagtgcta atgaaccttc tttatatgct
     9541 tttggtactg ctcttattgc tgtttctgat acagatatta ttgttggtaa catcattact
     9601 gctaatacta ttactattgc taacaaactt tgaccttttg gaagattaaa tatactttgt
     9661 atcattggaa ctatcactgc aagaccaaat acaccataca atactgaagg tatacctgct
     9721 aaaagttcaa ctgctggtga cattattttt gctaatcttt taggtgctac ttctgctata
     9781 aatacagagg ttaatatacc aacaggtact cctatcacaa gtgctccaag tgtcgcaaat
     9841 attgaagcta ctatcataga agatattcca aatttattgg cagaaggaac ccaatttgca
     9901 ccagttaaaa agtctataaa tgaatatcct tcaaatataa atggtcttaa tcctttataa
     9961 aatacgaatc ctattattaa aagtaaactt gcaactgcta ctaaagcact aagtagaaaa
    10021 atattttttg ctaacttttc aattacgtat tttgtcttat tgccattatt gtcatttttt
    10081 tctaaaccta ctaatctaga ctttactatc ataatatcct cccattaaaa tatacttatc
    10141 gattttcatt ctgtattcaa aatttaaatt tttacaattc gtcttcatca aatttcctgt
    10201 acttttattc tacttttttt aagttaaatc tatattagga ttaagttaaa caagtgtaaa
    10261 attatattca cttttttaac attaatttta cttttaaaac tatatttgac atttacttta
    10321 catataatgg tgttttgcta tattaaaata gcagatatag gtaataatac gctttatgtg
    10381 taatttatta cctatatctg ctattaagat ttgttaacta aatttaactt ttatactaca
    10441 tatataattg ttatctccta ttgtctatat cactattatt ttcataaaat tgttatgata
    10501 cttgatgttt acaataagta cgaatagaca aaaatataaa aataggtttt attaggctta
    10561 tgataaaaaa caacatttga aatgatattt tcaaacattg agcaccaaaa gttaaatcat
    10621 aaattgccaa ataaatagaa atacatacaa caaacattac tataaatata gcaaatagag
    10681 ctaatatttt agtaaatgct aagataagtg tatccatgtt tagtacaatg aagtatgcta
    10741 tatgatagtg tctgatattc acttcacaaa aaaaggtaga tgcaaagatt gcaacacata
    10801 caattaataa tatgaatata ttaaggataa aaatgaataa tatatagatt tatatataca
    10861 atttgtttat cttttcaaat gtaacccata aaataatggt gcaggtaaac atctttttaa
    10921 gtaataaaac tgactgtaat ttaactgata aagtctagta aataggcttt atcaattaaa
    10981 ttacagtcag ctattttata ataatttagt ttagatgtcg ttaaaatttc acatttataa
    11041 caagtattaa tatatttatt attccttatt aaaataatat cctgctcctc ttattgttat
    11101 aattttttga ggatttttat aatctttctc tattttcttt cttaatccat tcactgcaac
    11161 taccacacta tagttatcct ctaaatactc attcatccat acatgttcat atatctcttt
    11221 agtagtcaaa gtcttttcag gattctctat aaaaaagttt aacaacttat tttctgttgg
    11281 agtcaatttt attattttat cttctaactt tattactcca ctagttctat tatattcctc
    11341 taattttgta ttattttcat tattatttac atatgagttc attcttctta aaatagcttt
    11401 tacttttgca tataatattt ctaaatttag aggctttatt aagtaatcat ctccaccaga
    11461 atttaaggca tttaaaatgc tttggtcttc atttatgtaa gtaatataaa caattggaca
    11521 agtagttaca tttctaattt ttttacaaag agtccaccca tcaccatcag ttaggattat
    11581 ttctaaaaat attaaatcat atttattgct aaatattttt ccaatagctt cttcacagtt
    11641 atatgctaaa tctatactta ttcctttttc ttccataaat ttttttaatt tctggcaatt
    11701 atccttgtct ccatctatta tcaatatctt agtttgcatt ataatcactc ctaaatatca
    11761 ttattctttt atattaaata agctattatt ataaaaaaca tagacttaat tttattgtaa
    11821 aaacagttcc ttttcctagt tccgaatcta caaagatttc tccaccatgc tctcttataa
    11881 tggatttgac aatatataac cctaaccctt gcccttttgg attattgtta tctctttctg
    11941 taaagaatct atcaaatacc tttggtatat tttctggagg tatccctttt ccattatcag
    12001 aaattttaat aattgcaaat ccatcttctt catccattga caaaattatc ttcccatcaa
    12061 atggagtaaa ggttaaagca ttataaatta aattctcaaa cgctcttata agcatctctt
    12121 tatttatctt tgcatatatt tttttctcca atatgtaagt ttcaaagttt acaccacatg
    12181 cttgtgtatc tggcaagtta ttttcatata tctctttaat aaaatcattc agacatattt
    12241 tttcactaat accaatactt ttatcttgtg atgtaaattc ttgcaaacta cgtactctat
    12301 tttgtacttc atttgacttt tgatttatag cataaaggta ggttcttgtc tcttcatcta
    12361 catgaatatt accaaccttt atcaagtcta taaatgcttg tatagccgaa acaggtgcct
    12421 ttaaatcatg tgctacatct gccaaaaatt ttttacgttc atttaacaat gttgtaagtt
    12481 cattagttct cacttcaact tcatgttcaa gatttcttgt aagtttttca ttctctttta
    12541 ttattattct attcttattt atcatcataa cagaaaataa aataacaatt ataaacccac
    12601 aatattctgt ttgccaccct gtaaatatag gttcaaacct gttgctagta attgcatcaa
    12661 ataatatgct aattccaaaa acagtattta ctgaaactaa aatataagaa cttatatgtt
    12721 cagagcatgt ctttttatat attgaaacca gtgaagacat taatatatat ataaatacaa
    12781 tatatttata tatgtctatt aatttcccat atatgttgac aaagtacata tcatatggaa
    12841 gaagaataat tggtatcact atagacatga tactcattgt aattcctaat ggtaaaatta
    12901 aaaatctata caatttattt tcttctattt tggatatact tccatttata caaataatac
    12961 ataaaactgc tataaaatat gatgaatctt caactgcata tgtaaagttt actaaaggta
    13021 gtcctaacaa atgtacaaag ggataagata catgtatggc aaagaaaata cacatacacc
    13081 caaaatataa gtaaagttta cttttgtttg aaagaaacca tacagacaac gaaaatatag
    13141 ctattgcaaa agttgtgaaa caaattatac tataaaaaag tactctataa aacatcatat
    13201 tacttatatc ctttgtttct cctaatgcag gtggataata caaaccgcta taataatgtg
    13261 aaaaattcga tacattgatt ataatttctg tgtctttctt tgcaataaaa cttactacta
    13321 aatttttaat ttttggtcta tatttttctg ttcctacatc tcctaattta gaaaccattt
    13381 ctccatttat ccatacttca cttgcagaaa aaatctcagg aagctccaaa cttagtaacc
    13441 tattcttacc atcatttttt attctcatac gataagtagc attcccatat ggtgattgat
    13501 tcccttttct catagaaaaa tctggatatt gacctataaa aacatattct ggttttatat
    13561 cttgctctat aaaatcattc ggcttaaata ttttatgatt ataaaactcc cagtcatcta
    13621 tcaaaaatac aagtttactt ttagtgaaag tctcattatc tatatttaaa attccattac
    13681 ttgctctaat agacttgtgc gtatatttgt tatcatattt atacagaaga tttaatcctg
    13741 ttattgccaa cagagagact atcaatacaa tgagagttcc ttttagtata ttatactttt
    13801 tcattgcatc aaccacatct ctttcatagt agtgttaaat aaaataagaa ctatttatta
    13861 attacagcat ctcacctatg gtacaaactt atatcctttt ccccatacag tttgaatata
    13921 ttgatgctcc ctgcttaaag aattaatttt ttttctcatc tgtgcaatat gaacctgtac
    13981 tgtatgttga tccccaatat caggcatttt ccacacttgg ttatatattt ctatcttcga
    14041 gaatacttgc tctttgtttt cagctagaaa caacaatatt tcaaattcca tagttgttaa
    14101 atctatactt tctccatcaa aagttacttt tcttgaattt acatttatta ctaacgctga
    14161 aaactttaac acattaggaa ctgatgtaat atttttgtac tgcctcatac gagcatatat
    14221 tctaagttca agttctttta aactataagg ttttgttata taatcatctc ctccagctaa
    14281 aaatccccga actttttctt cttcatgctc ataattagat aaaaatatta taggtatgtt
    14341 aaccttttct tttatatcat tgcacatttt atatccatct atatctggca atgaaatatc
    14401 caaaattata caatctaaaa ctatactctc tactatatcc atagcatctt tagcagtctc
    14461 tgatgtatat acattaaaac ctatattaga aaaataaatt tgatttatgt ttaaaatatc
    14521 aacatcatca tcaacaacca gtaaattata cattacacca ctccattcaa aggtatttta
    14581 atcatagtct caagttttat aattattaca aattataatg ttttattttc atatataact
    14641 agtattatta ttttataata tctttacaaa ctagactata atacttaagt atttttgaat
    14701 aattcttgaa tattgtatta aacattaaga ctcattatta aatactaa
//
LOCUS       DBGJFK010000091        13607 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.093, whole genome shotgun sequence.
ACCESSION   DBGJFK010000091 DBGJFK010000000
VERSION     DBGJFK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13607
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.093"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            278..1216
                     /locus_tag="ACOIAP_003209"
     CDS             278..1216
                     /locus_tag="ACOIAP_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2640084.1"
                     /translation="MFRKVLYSLTLLSISIIFLVGCSNSQNKQNANENKEIQSQEDTK
                     KIDSSKDTSNVIVSDGIDKPSKNATNNDNNKLDVSSLDNTALDWFYIPNNKHKTPEVN
                     TDIGFKFSDYDAIYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTY
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKN
                     MVKFFRPPMGKYSEKSLAMTKNLRYKTVFWSFAYRDWDTKKQPPHEEATQKIMANLHD
                     GSILLLHAVSKTSTEILNDFITNARKLGYEFELLEY"
     gene            complement(1573..2946)
                     /locus_tag="ACOIAP_003210"
     CDS             complement(1573..2946)
                     /locus_tag="ACOIAP_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640085.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISVAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYMFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFIPVITGLIVTT
                     IVAMFII"
     gene            complement(3112..4434)
                     /locus_tag="ACOIAP_003211"
     CDS             complement(3112..4434)
                     /locus_tag="ACOIAP_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HGZ2640086.1"
                     /translation="MISKIKPSKLGVILLMYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNRLMDDFQTYVNNNGIRADDGDDIAKWNSDNWFVSIKIYKGNRVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIIVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSN
                     TLEKQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            complement(4427..5131)
                     /locus_tag="ACOIAP_003212"
     CDS             complement(4427..5131)
                     /locus_tag="ACOIAP_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640087.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LADSTIDLIILDVVMPVKTGFVACSEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEKEPNILKTKELCVNLDTQDVTLNGQPVF
                     LTTIEYSILVLMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            complement(5314..6378)
                     /locus_tag="ACOIAP_003213"
     CDS             complement(5314..6378)
                     /locus_tag="ACOIAP_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HGZ2640088.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFIMMFIYVACEGINIYLGMKALRQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGVMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVVGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVITSQI
                     EEYVKGAQYIKQNPKLVVQILVITIIQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     IVHVKSSEKVKSVKKVAYVR"
     gene            complement(6381..7079)
                     /locus_tag="ACOIAP_003214"
     CDS             complement(6381..7079)
                     /locus_tag="ACOIAP_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2640089.1"
                     /translation="MYVVGLIIIVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIIGLHSLEH
                     KNAWLYSYSYVKKDFIESTNIMKNLGVDVSYYRPPWGHTNIFSNLFVKKYNLKMTLWD
                     VMAEDWNKNSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKVAIPK
                     LKASGLKFVTPERM"
     gene            complement(7070..8167)
                     /locus_tag="ACOIAP_003215"
     CDS             complement(7070..8167)
                     /locus_tag="ACOIAP_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2640090.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEITIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDELLNEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHINHSTKKNILIMGGGLGLLPKSEQFYRELNDL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKGADLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDVTLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGECRECM"
     gene            complement(8492..9736)
                     /gene="glyA"
                     /locus_tag="ACOIAP_003216"
     CDS             complement(8492..9736)
                     /gene="glyA"
                     /locus_tag="ACOIAP_003216"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGZ2640091.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            10064..10852
                     /locus_tag="ACOIAP_003217"
     CDS             10064..10852
                     /locus_tag="ACOIAP_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGZ2640092.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            10852..11325
                     /locus_tag="ACOIAP_003218"
     CDS             10852..11325
                     /locus_tag="ACOIAP_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGZ2640093.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGITGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(11417..11857)
                     /locus_tag="ACOIAP_003219"
     CDS             complement(11417..11857)
                     /locus_tag="ACOIAP_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HGZ2640094.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGLKTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(11872..12165)
                     /locus_tag="ACOIAP_003220"
     CDS             complement(11872..12165)
                     /locus_tag="ACOIAP_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGZ2640095.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            complement(12208..12609)
                     /locus_tag="ACOIAP_003221"
     CDS             complement(12208..12609)
                     /locus_tag="ACOIAP_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640096.1"
                     /translation="MKKCLYCNRDIKSPNNNLSIKYDDNTNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILVFIVIITVLYFKQVGK"
     gene            12842..13489
                     /locus_tag="ACOIAP_003222"
     CDS             12842..13489
                     /locus_tag="ACOIAP_003222"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640097.1"
                     /translation="MKQIELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPSDAIILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDELIKKYVEKIIPTSYSTGELLLDANKFERQFD"
BASE COUNT         4689 a         2235 c         1609 g         5074 t
ORIGIN      
        1 ataaattaac ctactgttta attttcaaag ttcatttcac tcattcaatg tctttgtgct
       61 tgttattttg ttacttcttg ttgagcacat ttattataat aacaccttct aacaatatgg
      121 tcaactactt ttttcatttt ttttaaactt tattgattat tcacccattg tcatactatt
      181 gtgactttat ttttaagaat gtaactatta ttaataatag tttacaatta taataatact
      241 atatgtagtt gttattaatt cagaaaggag cttcaagatg tttagaaagg tattatattc
      301 tttaacacta ctttctatat ctattatttt ccttgttgga tgttcaaatt cacaaaataa
      361 acaaaatgca aatgaaaata aggaaataca gtcacaagaa gatacgaaaa aaatagatag
      421 tagtaaggat acttccaatg taatagtttc agatggaata gataaaccat caaaaaatgc
      481 tactaataat gataataaca aattagatgt atcctcttta gataacactg ctcttgattg
      541 gttttatata ccaaacaata agcataagac accagaagta aatacagata ttggatttaa
      601 attttctgac tatgatgcta tatacaatgg gcctacaaaa gatggtcaga aaacactata
      661 tcttacattt gatgaaggct atgaaaatgg atacaccaca aagatactcg acaccttgaa
      721 acaaaatcag gttaaagcag tttttttcgt tacatatcca tatataaagg aaaacaaaga
      781 tttagtaaaa agaatggttt ctgaggggca tatagttgga aatcacagta aaactcatcc
      841 atctatgcca acaaaaacaa gcaatttaaa aaactttaat gacgaattat atgatgttga
      901 aaagttatat aaagatgtaa ctggaaaaaa tatggttaaa ttttttagac ctcctatggg
      961 aaaatattca gaaaaaagtt tagcaatgac taaaaattta agatacaaga ctgtattttg
     1021 gagttttgca tatagagact gggatactaa aaaacaacca cctcatgaag aggcaacaca
     1081 aaaaataatg gctaatctac atgatggttc tatcttgtta ctacatgcag tttctaaaac
     1141 tagtacagaa attttaaatg attttataac aaatgcaaga aaactcggat atgaatttga
     1201 actacttgag tattaatgtt tagaattaca tctaaaatct acaaactagt atagttaata
     1261 tagtatatgt gataaaataa taatttaaaa ttagaatttt tgtttggtaa tagtataggt
     1321 aaaaaacttg tgatgtctta catatgttgg tagtacaagc aataaaaact caataaattt
     1381 ggcaagatac taaaatagat aatagtattt tagatgttat attagtataa caaaaaatat
     1441 tattctatca aagaatacta ttaaaaatat caataaaaat agatgtatgg cttagaatta
     1501 gtaaaactgt tatgataaat tatagctaca catctatttt tagtttgtat aattaaagtt
     1561 ttatttaatt cattaaataa taaacattgc tactatagtg gttacaatca atccagttat
     1621 aactggtata aaatttcgct ttgccaattc tattggacta actccacaaa ttgccgctgc
     1681 tgaaataagc ccccaaggaa ctaaacagcc tccacctacc catataccac tgatttgtcc
     1741 taatgcagcc aatgcaccaa cacttgcatt tatagcagtt ccaaacacag atgcaagtga
     1801 accaactaat gaaattccag aaaatccaga accatcaagt ccagttattg ctcccactac
     1861 agtttctata cctgatacag caaatttatt aagtggtatt gtctgagaaa gagctattcc
     1921 tatatctgat aataaacctt gtgaacctgg tgctaatacc tttccaaata cacctgtcaa
     1981 aggtgcaact tcacccatat agaaaaaagc tgctattggt ataattgcgc caaatatttt
     2041 tatcccaaac acaaaaccat caattatatt ctcacataca ttttcaagac tatctttgcc
     2101 aaaatttata acatttataa ttattattaa aaatactgct gttccaccta aaagagctga
     2161 tgcatctcct ccttttaggt caaacatata cattgcaatt atatcagcaa gaaatcctaa
     2221 agctactaaa atagttgcta ttttagattt tccattaaac tcttctactt cttcactttc
     2281 aaaacctttt agttcttctc taaacattcc tttgttaatg tctcttttca atgtataaaa
     2341 tgccacagat atggttacga ttcccatcac ccaaaacaaa atcataccat catttataac
     2401 atatgatact gcaactcctg ctgcaccagc tgttatactt ggagctcctt gaatgacaaa
     2461 gtctgtagat aaggcaagac catgaccaaa caaatttaat gctactgcaa caccaattgc
     2521 tggtagtcca gctctcatag caacaggtag aaatacagct ccaactaagg caactgctgg
     2581 agttggccag aaaaaccaag aaagaactaa cataacaaat ccagttacaa aaaatgctgt
     2641 attagaattt tttataaccc ttgaaaacgg tcttaccata tactgtatag cattattggc
     2701 ttctaaggct ttagataatg caaccataat agctataatt aagataattg gtcccaactc
     2761 atttaaagat ataataaaag agttaaacac tgctgttata gcaccaaaaa tatttttttc
     2821 aaagaacagt cccataaaaa aaacacctaa tatacatggt actattgtat cctttttcat
     2881 aatcatagta attaatataa ttaccataaa tagaatgtaa atataatgtg ctcctgtcaa
     2941 aaccatatta ttatgtcccc tttttttaag ataataatat tatatggttt tgtaagtaaa
     3001 cttgttactt gcctagagtt acacaatatc gaaccttcca taactaaagt cacagagttc
     3061 ctgcttcata gaattttgca taatcaatta cacaatatat aatttaaatt tttatgattc
     3121 ttttgctgga atagatattt caatagcaaa ttctttatca tctgagttta catttatact
     3181 tccattatga tatgcaacta ttttctcaca attctttata ccaattccaa aactttctac
     3241 attcttagaa aaattgctta ctctattttt ttgtataatt aataatttag aatcctctac
     3301 tttaattaaa aatactatag gtttatcttt cctagcatat tttattatat tagaacataa
     3361 attatcaaat atccttctaa attgtgtaac atctacataa atatgatatt ggttataaag
     3421 ttcattttct attgttatat gaaatccttt ctcctccaat gtatatgaac tatctaaaag
     3481 taattgaaaa ataaattcat tagcatttat tttttcatac ccttttgaaa cttcctctcc
     3541 agaattaaca aaatgggtaa aaaggtcatc tgttaaatct tttatttgat atgctttaga
     3601 ccttacattt tttatatact gttccaattg ctcaggacta ttatatttat ggtctttaat
     3661 taaatctaaa taacaaatta ctgatgttaa tggagttcta acatcatgtg atatcgaagt
     3721 tactatatct ttatttttat tcttcatctc tcgttctttt ataagttgct tctccaatgt
     3781 attgctcatc tcattaatac tagatgcaag tgatgataat tcatcattac cttttaccgg
     3841 gattctatat tttaaactgc cactctccac tatttttata cccatttcta ttttccttag
     3901 gtactttatc tttctactaa acaatagtaa gaatgttata ataaatgtaa gtgccataaa
     3961 tgtaatagaa attgcttcta taaaattttg aaacctaaat ctaaataaag ctactacaat
     4021 tatattagct ttaatatcag aaaattgtat ttcataattt ctagccattg gactgctata
     4081 aaactcattt tcctcactct tatcaggtac ttcattagga tagtataatg tatcataaaa
     4141 aaccctattt cctttatata tcttaataga aacaaaccaa ttatcactat tccattttgc
     4201 tatatcatct ccatcatccg ctctgatacc attgttattc acataagttt gaaaatcatc
     4261 cataagtcga tttacttctc ttttaaaata tactttccct tctgatacat cttttactat
     4321 agattcaaca gcagagtaaa atggtatatt taaaatgaaa gccactgcag ctgagattac
     4381 tacatacatc aatagtataa ctcccaactt agatggctta attttgctaa tcaatataat
     4441 acccctttcc ccatgcggtt tttatatatt gcggattttt ttggtctttt tctaactttt
     4501 ttcttaaatt tctaatatga accattattg tattatttgc tgtataaaaa tactgctcat
     4561 cccaaatagt ttcatataaa ttttcagatg agaaaacttt ttttctattt ttcaacataa
     4621 gaactaatat actatattct atagttgtca aaaacacagg ttgtccattt agtgtaacat
     4681 cttgagtatc taaattgaca cataactctt ttgtttttaa tatatttggc tctttttcct
     4741 tttccttacc ctggtatata taataacgtc taagtaacga cttaaccctt gaaattaatt
     4801 cagaatatga aaaaggcttt gataaatagt catctcctcc tgctgaaaat ccaataactt
     4861 tatcagaatc ttgagttttt gcagttaaaa ataatattgg tgctgtcgtt ttttctctaa
     4921 tttcactaca tgcaacaaat cctgttttta caggcattac aacatccaaa ataatcaaat
     4981 caatcgtact atctgctaag tttacagctt cttctccatt cgttgccata ataacttcat
     5041 aaccttcacc agttaaaagt atttctacga tttctctaat ttcaggatta tcatcagcta
     5101 ctaaaatttt ttttggaatt tctttattca tcaccaagct cctttttttg ctatatttct
     5161 taaatatttc aaactatata aaatattata ctttattagc aaaagcttag caatgtcaca
     5221 cgttttaata ccttctactt tggtaaacat gtttaaaact taattaaaat gtatacacaa
     5281 attgacatat taataaaaat aatctatata atattatctt acataagcaa ctttttttac
     5341 tgattttact ttttcagaag attttacatg tactattata catattaatc cacttatagc
     5401 tacaaatgcg taaaaactta ttcctctact aagtaacatt gccggaacta ataagtgacc
     5461 agggaaaaat atcttaaata atgtcataaa actattttca gaagctccaa cagcccctgg
     5521 caatggtaat gatgaaacag caatattaag caaggattgt atcgctaata tctcaaacac
     5581 agtatatgtt gatagatgaa aagctttgta tacaaagaaa ggaactaaaa acatagctgt
     5641 tatttgtata atagttatga ctaaaatttg gactacaagc tttggattct gctttatata
     5701 ttgcgcacct ttaacatact cttcaatttg agatgttata acttttcttg aactttcaac
     5761 atcttttatt attcttaact tacctaataa gtttgttatt gatattataa aattatttac
     5821 aagttttttt gaaaatataa ttgcaattac tccaacaaca agagcaacat ttgttattac
     5881 accatatatt agtaaaatgt tcataccgct tacattattt aatataaact cacgttccat
     5941 aataaacatt actccactat atgccaatat gactacttga tgaataacaa caatgactaa
     6001 tagtataagt gaagaatatg atatatttat atcatctttt ttcatataat aaacttgtgc
     6061 tggttgacca cctgatgctg aaggcgtaat agaactaaaa taaaatccaa taaaagcata
     6121 tcccatacat tttaaaagag ttgttttttg tcttaaagct ttcataccta aatatatatt
     6181 tataccttca caagcaacat atataaacat cattataaat ccaattagta taaacatagg
     6241 gcttgcacct tttaatgatt ttatcaatga ttcaactgac tgccctctaa aaacaaaata
     6301 tcctgttatg cccattagta aaactaaaaa agctacacta cctaggcatt tatttttctt
     6361 ttcagtttta cttatcataa ctacatcctt tctggtgtta cgaactttaa accactggct
     6421 ttaagttttg gaatagctac ctttaaggct tcaatagtac gctcaggtgc acctactgca
     6481 ccacctgaat tttcacctgc atcatgtaaa caaattatag aattttcttt tgttctactc
     6541 attaatttgt ttataatgat gtctactgta ctatttttgt tccaatcttc tgccattaca
     6601 tcccataagg tcatttttag attatatttt ttaacaaaca aatttgaaaa tatattagta
     6661 tgaccccatg gtggacgata gtagcttaca tctacaccta aatttttcat tatattcgta
     6721 ctttcaataa aatctttttt aacataacta taactataaa gccatgcgtt tttgtgttcc
     6781 aatgaatgta aaccaattat atgattttct ctcaacattc tttttataat ttcaggctct
     6841 ttttcagcat tctttgctac tacaaaaaac atagcttgta tatcattttc ttttaatacg
     6901 tctagtaatt tttctgtata tctcttatct ggaccatcat caaatgtaag tgcaatttca
     6961 ttttctccag ccatattttt taatacctct ttatttaata gtttattgta gtatgtaggt
     7021 ataattgaat ggactaaaaa aatcaatgca acaatgataa ttaaacctac tacatacatt
     7081 ccctacactc tccttgttca tcaagtgaaa ataaaatatt ttctaaggta ttattatcaa
     7141 actgtttttt taattctttc atgttactac tcatttcttt aagagtaaca tcatcataaa
     7201 ttaaatcttt tatctcatct acatagtatt ttttattttt accaagtatt ctcccaattt
     7261 cattatttaa tataaaacta gcattatcta tctcttgttg taaaaatgga ttaaatgcca
     7321 atattggaag ttctgaataa attgtttcga atagtgttat tccacctggt ttagaaataa
     7381 taaggtcagc acctttcata tatttatata cttcattggt gtaacctact acctctatat
     7441 tttcatatct accatatagt ttatagtaca tttttttatt attaccagtt attacagtag
     7501 tctttactcc ttctaaatca tttaactctc tgtagaattg ttctgattta ggtagtaatc
     7561 ctaatcctcc acccattata agaatatttt ttttagttga gtgatttata tgttctattc
     7621 ttttaaattc tttttttact ggaataccat taactttaat cttagattca tctattcctt
     7681 taaaaacaag ttcttcctta gtggatttac tagctactaa ataacaatct gtatttttac
     7741 taatccattc tgagtgacta cttatatctg ttatgcatgt aattaaagga aggtttgagt
     7801 tatacttttc cttatatctt gatactaatt gagaacaaaa tggaaaagtt gaaataacta
     7861 ctgttggttg tacttcatta agcaattcat ctaatttatt taaaaaataa tctgaaaaag
     7921 taaattttat atctttcttt ccattttcag cacacttata aaacaaatta taaagactac
     7981 ttccccgatt tacaagaata gaaaaagtct tgtacatttt atctgaatag ttaggcataa
     8041 tatattcaaa tatatcttta attgttattt ctgaattatc aaattttgct tttatatctt
     8101 cacttaaaga atttgatgct gaataatgac ccataccaaa ttttcctgta agaattaata
     8161 ccttcataag attccctcct aattaaagct tttcttttca tataattact atacttataa
     8221 gtatagactt taaatcttta gaaaaaccta gtataattct taagaaatct taaagtttta
     8281 attaaaaaat acaaagagac catctaaaaa tagagataac cgtatttttt attatttaaa
     8341 taacacaaat atgttcgatt ccatacaaaa aagagtgtct catgaactaa aaagttcatt
     8401 ttgagacacc ttttttatat ctacatgtat tcaaatacat acacaatcat tgtaattatt
     8461 taaatgtatt ttatttagtt gttctttata attaatccat aatattatat tcttcatata
     8521 aaggatattt ttcagttaaa ccaacaacca atgttctagc cttagattct tcatcataag
     8581 ttaaacatag gtctatagct tcagctatta ttgccatatc ttcttctttc atgcctctag
     8641 tagttacagc tggagtccca agtcttattc cactcgtaac aagagcacca tttggatcaa
     8701 atggaattgt attcttatta gctgttatgt aagcatcatc caatcttttt tctgctgctt
     8761 taccagttat atttttatta gttaaatcta atagtattaa atgattatct gtacctccag
     8821 aaatcaattt aaaatctctt ttaataagtt cttcagctaa ggcttttgca tttttagcaa
     8881 cttgtacttg atattcttta aactcatcac ttaaagcttc tttaaagcaa actgccttag
     8941 aagcaattat atgttcaaga ggtccgcctt gaataccagg gaatattgct ttgtctatat
     9001 ctttagcata tttttctttg caaagaataa cacccccacg aggtcctctt aaagttttgt
     9061 gagttgttgt tgtaacaaaa tcagccactt cacatggatt ctggtgaaga cccgcagcaa
     9121 caaggcctgc tatatgagcc atatctacca taagcaatgc tccaacttca tcagctatct
     9181 ctctaaactt tttaaaatct atttctctag gatatgcact tgctcctgca actatcattt
     9241 taggttttac ttcatgtgct atctttctaa cttcatcaaa atctataagt ccactgtctt
     9301 tatctatacc atattcataa aatttataat actgaccaga aatattaact ggagcaccat
     9361 gagttaaatg tccaccttga gataaattca ttcccataac aacatcacct ggttttaaca
     9421 tagcaaaata tacaccaata tttgcatttg ctccagagtg aggttgaaca ttagcatgct
     9481 ctgctccaaa tatttttttg attctatcta ttgcaagagt ttcaacttca tctatatatt
     9541 cacacccacc ataatatctt ttgcctgagt aaccttctgc atacttattt gtaagatgac
     9601 ttcccatagt ttccattact ggaactgata ctatattttc agatgctatt aattcaatat
     9661 ttctttgttg tctttttaac tctcttttca tactttcata aatctcagga tccgcttttt
     9721 tcaagttctc aaacatatta ctcctcctag ttattattta aattttattt ttacagacat
     9781 ttcataattt tcgtttttat caatatgata atttattatt atagtccttt agcaattaat
     9841 agtcaagtgt tttgccattt ttccatattt aacataatta ctttctttat ttttaagtta
     9901 aaatataata aataatattg tctaattctt ttaattggat ataatttaaa tgtgactatt
     9961 ttgaaacaaa aaaaagataa tatatttata tagatattaa ggaatattac ttaaaaattt
    10021 gatataattt caatattacg ttttttaatt tggaggtgta tttatgaatc aaaatgagga
    10081 acttgaatat aagaaaaata ttctaaaact agctctattt gtaggggaac ttatgataaa
    10141 aaatggagct gaaacatcta gggttgaaga cagtgtcctt agaatatgca ggtcaagagg
    10201 gttttatcat gtaaatattt ttacaactcc tacagtaata attatttcag atgagaaatt
    10261 tgatggcttt tcgtttatga aaacgattca atcaagaggt ataaacttaa ataagatttc
    10321 tttattaaat agtttttctc gagaatttgt tagtgacaaa gagtatgata ttgataatgc
    10381 tattgcacgt ctttatgaaa tacaagatgt aaaaccttat cctttatggt tattttactc
    10441 ttgtacagga attgcatctg cttgttttgc ttgtttgctt ggagggaatt atgtattaaa
    10501 ttttatactt acgtttataa tagcaatctt tgctgcaatt acttatgata aaacgatgaa
    10561 gataagtgca atatctgcgt tttcctgttt agtatcttct tttttaattg cactttcagg
    10621 agttctgcta gttgaaatag gcattttaga tgaccctaaa atgcttatag tcggcgccat
    10681 aatgccacta ctcccaggag ttgcttttat aaaagctatt agagatttaa tatcaggtaa
    10741 tttaatatca ggaatttctc gtgcttttga cgctgctatg attattattg caattgcttc
    10801 tggagttggt tttgttcttg atacatggta tagaatagga ggtcctttct aatgactgat
    10861 atgtcaatga ttttacattt tttattttca ggcgttgcaa ctgctggatt tgctgttttc
    10921 tttaatgctc cactctatct acttcttcca gctggaataa ctggaggaat tggttggatt
    10981 gtatatgttt atttatttaa ttttactaca aatgccgttt ttgcaggttt tatagctgct
    11041 gctttggtct cagcatgcag tgagactttg gcaagaaaac taaagcaacc agctattgtg
    11101 ttcgtaattc cagggattct tcctctaata ccagggattg ggctatataa tacaatgttg
    11161 tctttgattc agaagaatta ttctttggct atgtcaaaag gtacagatgc gctatttcta
    11221 agtgctgcaa tagcacttgg tgtattagtt gtaacttctt ttgtaaggac attgaatctt
    11281 ttgaaaatca gaaaaaactt tattccttac agaaaatcaa aataaaaata taaaaatagc
    11341 aatgtactta aactttataa atacacattg agtatttatt taaaaagcac attgctattt
    11401 tttaattata attatcttaa aggtcaatta atattcgtgt tattactggt ataaactctc
    11461 tactgtctct gaattttttg tcattcttct ttaagtataa ataacaaatt attgtaagac
    11521 aaattccaac tagtccactt atagcttcaa ctccagtttt cagtccaatt gcccccaata
    11581 tataataagt ccctattgtt cctacaagaa gtgctataag aggtattata taagccatta
    11641 cagctgcttt taatacattc atattatcca tactcacttc tacatggtca ccaacttttg
    11701 caccaattgt gttgtctact tctactaata tttcttttga ctctgctgaa tttgtagtag
    11761 cacattttcc acaagcagca caagctgaat gtctttgcat ttttaacttt gcagttctat
    11821 catcaacaat ttccataata aatccttgtt gattcataac taaccgcctc cttattttgt
    11881 aaatttattt atagtatcca taagctcttt tatcatctct tcagttttat cagcatcatc
    11941 atgtttgata ctttctgcta cacatccttt tatatgattc tctaagataa ttgtgcctac
    12001 tctatttata gcagacctta tagcagatat ttgaaccaat atatcaacac aataacgttc
    12061 ttgttcgacc attttttgta tccccttaac ttgaccttct attcttttta atctttttat
    12121 gagagcttcc ctctcattgt ttggtgctaa ttttctctct tccataaatt cacctcatac
    12181 tctaatgatg tcttatgcaa ttatgctcta cttaccaact tgtttaaaat ataatacagt
    12241 tattattact ataaatacca aaattgatat tgcaatagac ctgctttgat tcttagtttg
    12301 ttccatactt aactttccat tcatcttaaa tcctgccaat gggaataaaa atataaccag
    12361 tgcatcaatt ccaagtacaa cttgggctgc aatagtccat ttgctcaaaa agcagaatat
    12421 tccacccaca cctaaaagaa cctctaatat atttataaac ttatatgtag gtttttttgc
    12481 tatatattct tcaatttttt ccttacattc tgcacgacat ggatatatat tcgtattgtc
    12541 atcatatttt atagataaat tattatttgg tgactttata tccctattac agtaaagaca
    12601 ttttttcatt ttatattctc ctctagtatt ccttaaaaaa ttttgcctaa attattatac
    12661 gctataatac tattatacca aatagataca aaaaacaaaa ataaaaggaa taattttagc
    12721 tatttctttt atttcaatgt gtagtctata ataaatttat aataacaatt aaataatatt
    12781 atttagtcta atttaattgt tatgtaattt aaaataagtc aaatttgtat gagaggttaa
    12841 aatgaaacaa atagaattag ctattgtaag tttaaaaaaa gacgctggag aaatttatga
    12901 aaatcaaata aggcaattct taggtgataa tctaaagata aatttatact catttgaaga
    12961 gggaaattta aagtttttta aagaaaaact tatactccta tctgcttact taaaatatga
    13021 tgaaatagta aaattatctc actatgatgc tcaaatcatt gttcccaagc tgacatttga
    13081 aaagaacagt attgatatga tatccaaatt agaaaaagat aaaattattt atgtatataa
    13141 cttaagtaaa gatatggcaa tagaaacaat ttctttaata catagactag gaatagacaa
    13201 tatcaatatc ctgccctgct atccagagat tgagtttact ccctcagatg ctataatcct
    13261 aactcctggt gaaaaaatct tgcctaagtt taaaaattgt gaagttatag atttaaaata
    13321 cagaataata gatttaagtt gtattgttga aattgctaca aaaaccaaat taaaacacct
    13381 aataaaagat gagctaataa aaaaatacgt agaaaaaata attcctacaa gttatagtac
    13441 aggtgaatta ttattagatg caaataaatt tgaaagacaa tttgattaaa aaatagctac
    13501 gaacacttgt gactttagtc atgagttagt agctaaatta gtcagcatat agggaaacct
    13561 atatgtagag ataggataga acctatccaa tactacttga attgctg
//
LOCUS       DBGJFK010000092        13588 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.094, whole genome shotgun sequence.
ACCESSION   DBGJFK010000092 DBGJFK010000000
VERSION     DBGJFK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.094"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(327..1370)
                     /locus_tag="ACOIAP_003223"
     CDS             complement(327..1370)
                     /locus_tag="ACOIAP_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGZ2640098.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHLLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQIATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEIFD
                     VKEALGDNESLKK"
     gene            complement(1391..1837)
                     /locus_tag="ACOIAP_003224"
     CDS             complement(1391..1837)
                     /locus_tag="ACOIAP_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HGZ2640099.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVVLIFLSSFIESI
                     FLQILIFAVISIAMLVIATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVNATTSVTNQ"
     gene            complement(2007..3587)
                     /locus_tag="ACOIAP_003225"
     CDS             complement(2007..3587)
                     /locus_tag="ACOIAP_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HGZ2640100.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTCGKEVNVFLVGNIEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYETSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRREKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     SKLLSSSDAIGFGPGMGNNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNVVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDELSKTMYTVN
                     ATDLISNISLTMKELLDI"
     gene            4387..5289
                     /locus_tag="ACOIAP_003226"
     CDS             4387..5289
                     /locus_tag="ACOIAP_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640101.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            5276..6031
                     /locus_tag="ACOIAP_003227"
     CDS             5276..6031
                     /locus_tag="ACOIAP_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640102.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTSPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            6162..7184
                     /locus_tag="ACOIAP_003228"
     CDS             6162..7184
                     /locus_tag="ACOIAP_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD0873 family tyrosine ABC transporter
                     substrate-binding lipoprotein"
                     /protein_id="HGZ2640103.1"
                     /translation="MINKKRLASLILAGALSVSMLTGCSQGGDSGNSKQESNSKSKEV
                     KKIGITQLVEHPALDATKAGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILMTAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNKNISY
                     VKTKQE"
     gene            complement(7346..7903)
                     /locus_tag="ACOIAP_003229"
     CDS             complement(7346..7903)
                     /locus_tag="ACOIAP_003229"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HGZ2640104.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEGEYGK
                     REAILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APSVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGVTIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(7930..8985)
                     /locus_tag="ACOIAP_003230"
     CDS             complement(7930..8985)
                     /locus_tag="ACOIAP_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HGZ2640105.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISQLNRIDKNTIYAIDWGCELTLDREIVDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIIENPFTYTMYVRKTNLSNECVPIQIELEKSKMRFKK
                     GDSIYLDFPQEYLFCFK"
     gene            complement(8986..9669)
                     /gene="modB"
                     /locus_tag="ACOIAP_003231"
     CDS             complement(8986..9669)
                     /gene="modB"
                     /locus_tag="ACOIAP_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HGZ2640106.1"
                     /translation="MGTDWSPLWISLKTALLSTVITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLSFDKTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKVAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVVISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(9818..10630)
                     /gene="modA"
                     /locus_tag="ACOIAP_003232"
     CDS             complement(9818..10630)
                     /gene="modA"
                     /locus_tag="ACOIAP_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2640107.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNESKKDDGKQEKTNKSSDSIE
                     LNVSAAASLKEAMAKIEEEYKKIDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSNVTGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSEEGQKIFEEFGYKKVE"
     gene            10823..11752
                     /locus_tag="ACOIAP_003233"
     CDS             10823..11752
                     /locus_tag="ACOIAP_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGZ2640108.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     IKDVEEYINIQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEIKTWDDLTKSNITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGIGGYDLTDTGKTIAKV"
     gene            complement(11914..12363)
                     /locus_tag="ACOIAP_003234"
     CDS             complement(11914..12363)
                     /locus_tag="ACOIAP_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640109.1"
                     /translation="MKNKNNKDKNMFNIKVLRVLGLLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGADCIVFLLFIVECVYLVGRYILKVKINWSDIIESEKDNFINNLLVEKI
                     QEESNIVYNLLNSYVLPYIYKKGKGLMSKTYHMLIYIKEKYYYVNIY"
     gene            complement(12565..13437)
                     /locus_tag="ACOIAP_003235"
     CDS             complement(12565..13437)
                     /locus_tag="ACOIAP_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2640110.1"
                     /translation="MYNSSVGLEQLIKNEDIVKIFSERKDKPLDKLKNYKTAELMIQS
                     SNNYKLESLFITSNIKTRDTIILVHGIGSSYYEMLKVAYGYLDKGYNVLVYNQRNTGN
                     SGGDNYTFGLYERYDLDSLVKFVKNKFPEGRLGVHGFSMGAGTAAMHTEINSKNEKVD
                     FYILDSPYSEMKDAIRMGVLEKRIPGILIDYVVTCGDLYNKFKSGFWYSDVKPYESVE
                     KSNVPILFIHGTKDTVCNYQNSKKMYDLVKHDKKELWFIEGIGHVDGFEHDSTVYFNK
                     IFKFIDSNVLSDKS"
BASE COUNT         4592 a         2259 c         1546 g         5191 t
ORIGIN      
        1 atataaactt ttagattatt tattagtttt cttattttaa tatatatttt tttataaata
       61 tatattaata atacaaatag actaactaaa accatgctta tttgctatat gttttatata
      121 atattatata acacttttta cattagtaaa gaataaattg tataaaaatt ctgttaattc
      181 atctttataa tttcatcttt ataataaaaa caaagaagaa gacttaaaaa tttataagtc
      241 ctcttctttt caacgtgcat ttttttacta tatttaatta attcgacctt taatttccat
      301 atccttccta tgataacaaa actcttttat ttttttaatg attcattatc acctaaagct
      361 tcttttacgt caaatatttc tttgttatca tcactcataa cttcttttat tcctttgaat
      421 gttcctaaga aattaactgc ttctgaaggt aaaaccagtt ttgttgactt accttcagcc
      481 attttttcaa gagcttccat agattttaat gctagaatat tattatctat atcagcctct
      541 ttcattgctg aaaagactag ttttaaacct tctgctgttg ctatctgagt tctttttatc
      601 atttcagctt caccttgtgc cttagcaata gctgtctgtc ttatagcttc agcctcacct
      661 tctgccacta atatagcaga ctctttttca ccttctgcta cacgtaccat agcttctttt
      721 ttagcttctg ctgttaatat agcagattgt ttttcacctt ctgcttgaag tattgcagct
      781 gacttattac cttctgcttg aagtattgcc tctcttcttt ctctttctgc tctcatttgt
      841 ttttccatcg caacttgaat atcctgagga ggcattatat tttttaactc tactctattt
      901 acttttatac cccatttatc tgttgcttca tcaaggatag ttctcatttt tacatttatt
      961 atatctcttg atgttaatgt ttcatctaaa tcaagttcac caattatatt tcttagtgtt
     1021 gtagctgtta aattttcaat agcagctatt ggattagcta tctcaaacac atatctaact
     1081 gggtctgtaa ctttataata tacaactgta tcaatctgca tagttacatt atctttagtt
     1141 ataactggtt gaggtggaaa atctattaca atttctctaa ggtcaattac atatgccatt
     1201 ttatctaaaa atggtattaa taaatgtaca cctgtttcag ccactttttg aaacttacca
     1261 agtctcatta ttatacctac tttagattgt tttataactc ttatacaggt taaacttatt
     1321 gctacgacta ctactattaa tacaatactt aaaacaattt tagtacccat actataaatc
     1381 ctcctttatt ctattgattt gtcacactag ttgtagcgtt tactttttta acaactagtt
     1441 ttaccccttc aatttttaat acttctactg tagaaccttt ttctatcttt tcaccatcta
     1501 tagaaatagc cgtccatgtt tcatgttcaa ctacaactag acctgtatta tttggagaaa
     1561 tctcttctgt aacaatacct tttttagaca tcattgcttg taaattagtg ttagatttgt
     1621 agcctttatc tttttttact atttttttag tagctatgac caacattgct atagaaatta
     1681 ctgcaaatat taaaatttgt aagaaaatac tttctataaa actacttaaa aatataagta
     1741 ctacagctcc tacactaaac catatcaatg ttaagcttgg tgtcaacatt tctgctattc
     1801 caaataagac tgctactatc aaccatatta acttcatact atctaccctc ttttcatatg
     1861 aattataaaa ccctatataa attatatgtt tatacaatgt ttttgaatat aaatttaaat
     1921 tacaaaacaa taaaataaat taattaatag tattatatca acatactttg ttaaagttgt
     1981 tacaaagtag tatcaaatat cattaattat atatccaaca actctttcat tgttaatgaa
     2041 atgttactta ttaaatccgt agcatttact gtatacattg ttttactcaa ttcatctcct
     2101 atatagccat gtatatatgc tccactaact gtagcttcca atatatccat accttgacct
     2161 ataaatgaag taatcattcc aagcaaacaa tcccccattc caccagttgc catacagcta
     2221 tttcctgtag gatttatata tgttttttta ccatctgtta tgacagtttg ataacctttt
     2281 aaaagcacaa ccacattata tttttgagca aattcttttg caacatctac tctatgttct
     2341 cttatatacc caattgaatc tcctgtcaac ctggccattt ctcccaaatg aggtgtaatt
     2401 acaaatctat ttttccattc taaaaactta taacatctgt ccttcataac gttcaatcca
     2461 tcagcatcta atactatcgg gcaattagaa ttttcgacta tcttaagtaa tttatcaaat
     2521 gtttgactat tgtttcccat tcctggacca aaaccaattg catcactaga actaagtaat
     2581 ttacttaatc tttcctcttc aaaatttaaa gtcattgctt ctgtaagtct aatagatacc
     2641 ttttcttgca catcttcact actaattaaa gttacaagtc cacttccact cttaacagca
     2701 gattcagttg ctatgaaact tgcaccataa aatccttttg aacctgcaac tatagatact
     2761 tttccaaaat cacttttaaa accatgcttc tctcttcttc taatattatt ttttacaaaa
     2821 gtcttatcag ttatgaactc ttcatcatgg tattttcttg taataaaatc tggaacacct
     2881 atcttttcta caactacatc acctataagt gcgctagtct catagtttag aaaacctctt
     2941 ttataaaact caaagctaat cgttttgttt gctctaatac aagttcctaa tacatttcca
     3001 ttatcgctat ctatacctga aggaatatct atagaatatg tatttttgct attatcgttt
     3061 actatgtcaa taacttcttt aaaaatacca gttatatcac gttttagtcc agtcccaaat
     3121 atagcatcta ctacaacatc acttttagat actctatctt taaaaattgt taaattttta
     3181 ttttttataa tattttgttt ctcaacttta ataattttat ctacttcatt ttcatctcca
     3241 taattttttt cacttaaatc atttttatta atatttataa tattaattcc catatttaaa
     3301 agtacattgt aatttatttt agaacattca cttagttttt caatattacc tactaaaaat
     3361 acgtttactt cttttccaca tgtatttaga tgtcttgcta ttccaagacc atctcctcca
     3421 ttatttccaa caccacatac aactgtataa ctattataca tgtctatatc catatttttc
     3481 attgcagata taactgcatt ttccatcaat acaatcattg gaatacctac ttcttctaca
     3541 catgcagtat caacatttct acttaactta gatgtaccta ttagcataaa ttatcactcc
     3601 tataaagtta aagacttctt aaatattcat aaaaaaatat ctattgaaat ctttctaagc
     3661 acataaatat cataaataaa atcactaaaa ctaatatttt tgaaataatt taaaataaca
     3721 aaaaattttg aattaaagta attatttaat ttattatacc atataaatta agctattatg
     3781 ttgatttaaa acctatttac actaattatc taaatatttc tttattttca taatctttta
     3841 tgacttattt atatttttca tttttataaa aaaacaataa ttaagaatat aactatattc
     3901 tacacataaa aatttttttg tttaaactta attttctgat aatttgataa tttttcaaaa
     3961 tttatagttg acttttattt tttactgtat taaactaatt actatacaaa acggaaaaca
     4021 aaattttcaa aattattaaa ttaaaaggag aggtaaatat gaagacttta ttaaacaaac
     4081 aagtacgatt ttttagtagc caatttagtt agggtttgta cctaagttaa gacgaattgt
     4141 cataacatag atacaagccc cttaggatta tgatttttaa ggattgtatc tatgttggct
     4201 atagtaattg ttgttaaagt ttttatttta tcatcataat atagagccac atggattata
     4261 ctgtgtggct tattcgtatt tttgccatac agttgtatat actgtgtggt ttttttatat
     4321 caaaattgag ttttcaaatt aaattcaaaa atttatttaa aatattttca aaggggtgtt
     4381 ttatttatgt caggtattat atctgtaatg acgcaaagtt taattttatc gattatggca
     4441 ctgggggttt atataactta caaaatccta gatttcccag atatgtctgc tgatggtagc
     4501 tacacaatgg gtgcttctat cgtagcattt tctcttacta atggtatttc tcctgtggta
     4561 gcaactttaa tggctatctt atgtggttgt actgctggtc ttgttacagg gattcttcac
     4621 attaagttta agatatctaa cttactttct ggtattttag tcatgggaat gttatactct
     4681 atcaacttaa gaataatggg aaaatcaaat attcctctat ttagctttaa acacttattc
     4741 aatggagaaa tatctcctat agttttagcc ttagcttttg tattcatctg taaagtcctt
     4801 ttagacttat tcctaaaaac aggtcttgga tacactttaa agggtgttgg tgataactct
     4861 caaatgatta agtctctagg tataaatatc ggttctataa aaatactagg acttatgatt
     4921 tcaaatggac ttatagcttt atctggtagt cttatggctc agttcttagg attttcagat
     4981 gtaaatatgg gtataggaac tttagttctt ggaattgcct ctatcataat tggtattaca
     5041 ctatttaaga aattcacttt tatcaaagat actactgcaa taattgttgg ctcttttata
     5101 taccaattca ctatatactt tgcaatgagt ttaggaatgt tatcaactga cttaaaatta
     5161 ataactgcca tagttataat agctttctta gctactggta acttgaatat ttcactaaaa
     5221 aaaaacaaat gcaaagctag taccaaaaat aaatcagaaa aaagaggtgt tgtagatgtt
     5281 acaaattaaa aatctttcaa agagtttccc caatccatac ggtgaaccta atactatatt
     5341 tgaaaattta tcaattgata tagaagatgg tgaatttgta agtatcatag gtagtaatgg
     5401 aactggtaaa tctactttat taaatataat ctctgggctt ataaaggaat cttctggtca
     5461 agtattatta aataaacata acttgtctaa tttagctgaa cacagaagaa ctcaaatagt
     5521 aagtagagtt tttcaagacc caagtcttgg aacttgtcct tctatgactg ttagggaaaa
     5581 cttgtcttta gctcttaata aaggaaaact attaaaccta agaaaatgtc ttcgttacaa
     5641 aagagatttt ttagaaaatt tattggaagg tgtatctctt gatttaaaaa aataccttga
     5701 tgttcaagta aaatttttat caggaggtca aagacaatca ttatcactaa ttatgtcgtg
     5761 cttaacaagt ccatcagttt tattacttga tgaacataca gcagcacttg acccaaaaac
     5821 atcaaatgaa gtaattgaat tgactaataa gattgtaagg gaaaaaaata taactacact
     5881 tatggttact cacaacttaa aacacgctct tcagtatggt gatagattga taatgcttca
     5941 taagggtgaa gttgtattag atgtaaaagg taaagaaaaa gaacaattaa cagttgaaga
     6001 aatcttagaa aaatttgaat atgcagttta aaataatata tctattgtat taaactcagc
     6061 tttaaaataa agttaaaact ataataatta tggttacttt acaataattc atatgaatat
     6121 atgaacatat ataataataa atttttgagg gggatataaa aatgattaat aaaaaaagat
     6181 tagcaagttt gattttagct ggtgctctta gtgtatctat gcttacaggt tgttcacaag
     6241 gaggagactc tggtaattca aaacaagaaa gtaattctaa aagtaaagaa gttaaaaaaa
     6301 ttggtataac tcaactggtt gaacatccag cattagatgc aactaaggca ggttttgtaa
     6361 aagcattaga aaagaacgga tttaaagatg gagaaaatat tgatatagac ttccaaaatg
     6421 ctcaaaatga tatgcctact acacaaagta ttgcaagtaa atttgcatct gacaagaaag
     6481 atttaatatt tgctatatct actccatcag ctcaggcagc atttaatgct actaaagata
     6541 tacctatact tatgactgct gtcagtgacc ctgttgctgc tggattagtt aaaactcttg
     6601 aaaagccagg cacaaatgta tctggaacat cagattttgt ttctgtagat aaaggtttag
     6661 aacttcttaa gatatttgct cctaaggcaa aaactatagg agttatgtac aatactagtg
     6721 aagtaaattc caaagttcaa gttgatgctt taaaagaata tgcatctaaa aatggcttta
     6781 aagttgttga aaaaggtata actacttcaa atgaagttaa tcaaggtatt tctagtttag
     6841 ttggtaaaat agatgtatta tatgttccta cagacaactt agtggcttct tctatgccta
     6901 tagtttctaa aatagctact gagaataaaa tacctgttat agcagctgaa tctggtccag
     6961 ttgaaaaagg tgctcttgct tgtcaaggta tcaactacga aaaactaggt tacaaaacag
     7021 gtgaaatggc ggttaaaatt ttaaatggcg aatcagtatc tgacatgcct gtggctacat
     7081 cagatgatac agatatcatt gttaatgaag atatattaaa agctttaggt atggaaaaac
     7141 cttctaataa aaatatttct tacgtaaaaa ctaaacaaga atagaaagat attttctata
     7201 tacgattaat atgtccgttt ctataaatta atttatagaa acaggcatat atttttgttt
     7261 taatgtatta tttatttaaa gattatataa acgctcttaa tttattttta taaattttac
     7321 ttgtataaac tttgtacaat catattcatt cttctatttt ctttattact ctacatggat
     7381 ttccaacagc tacagtattt ggtggtatat cttttgtaac tacacttcct gcacctatta
     7441 ctacattatc acctatagta actcctggtg ttatgattac gcccccacct atccatacat
     7501 tatcacctat ttttacagga gagccatatt ctatacctga atttctaagt tgtgcatcaa
     7561 tcggatgata ggctgtatag atttgaacgc tcggagctaa cattacatta tcacctattt
     7621 caatcttaca aacatccaag aaaatacagt cataatttgc aaagaaattt tcacctacat
     7681 gtatgttata tccataatca cacctaatgt tttgttctac atttatttgc tttccaactg
     7741 aaccaaatag ttgtcttaaa atagcttctc tttttccata ttcaccctct aaagtattat
     7801 taaatagtct agttaatttt ttacaatact ctctttcttt tactagcaat tcatcatttg
     7861 catagtaacc tttcccagac aacatttttt ctttttcggt catataattt actccttttt
     7921 attgtaattt tacttaaagc aaaataaata ttcctgtgga aaatctaaat aaatgctgtc
     7981 acccttctta aatctcattt tacttttttc taattctatt tgaataggta cacattcatt
     8041 agataaatta gtttttctaa catacatagt ataagtaaat ggattttcta taatattaat
     8101 caattcaaaa cataactttt catttaaatc ttcattagaa tccaagacct taatgtgatg
     8161 ctctctaatt cccacatatt ctatattatc aactatttct ctgtctaatg tcaactcgca
     8221 tccccaatct atagcataaa tagtattttt atctattcta tttaattggg atatattttt
     8281 gcaccctgtt atcttagctt ctataaggta ctttggagat tcaaagagtt cttttttagg
     8341 tctctttgga agaccttctc ccttgttata cactataatg tcatcgcaaa ctcggtaggc
     8401 ttcttcaata tcatgagtaa caaatagtat atctccctta taatctttta acatattcat
     8461 aagttctttt tccatattgc ttcttaagtg atggtccagt gctgagaaag gttcatctaa
     8521 aagtaatata tctggagatg ttgccaatgc tctagctagt gctacccttt gttgttgacc
     8581 accagataat tgccaagggt atctaccctc aaacccattt aatttaagta tatctaaata
     8641 ccttgctact atttcctttt tttcactctt gcttagtttt aaaagcccaa gttctatatt
     8701 ttgacttaca gtcatatgtg gaaacaaagc atagttttga aataagaaac ctacctttct
     8761 atcttgtgtt gataaattta tcttcttttc agaatcaaat agaactctat catttaatac
     8821 aattttacct cttgttggct tctcaagacc tgctatacat tttaatgtca tactttttcc
     8881 agaaccagat tctcccaaaa accccagcgt acctttttct tgtttaattt ctacctttaa
     8941 tttaaaagag gataaatctt tttcaatatc tacgtataag ctcaactatc cacacctctt
     9001 tcctataatt ttctgctgaa attccgacca ataatttagt aataaaatca ttgctataga
     9061 tattactaca ataatcataa cccacatcat agctttattc atatctccac cttcaacagc
     9121 aaaaaatata gctattggca tagtctgagt ttttccaggt atatttccag ctatcataag
     9181 cgtagcacca aactcaccaa gagctctggc aaatgacagc actaatccac caattattcc
     9241 aggccatgct aatggaactg caaccttaaa aaatactttc cattcattaa gacctaatgt
     9301 cctagcagct gacaacatat tattatcaat ctgttcaaaa gctgaccttg aagttctata
     9361 catcatagga aaagatacca ctactgctga aattacagtt gctgtccaac taaatattaa
     9421 agtcttgtca aaacttaata aaaacttccc tataaatcca ttcttcccac ataacaataa
     9481 taaaaagaat cctacaactg ttggtggcaa aattagtgga agtgtaaata gtccatctat
     9541 aagacccttc cacttacctc tatagttagc cataatatat gacacaaata ttcctattac
     9601 aaaagttatt actgttgaca aaagagctgt cttaagtgat atccataaag gtgaccaatc
     9661 tgttcccatc tttccctcct taattttaaa tggaaatagt gaaattaata actctattaa
     9721 tttcactatt tccattttat tataatacac aattattttc aattttcatt tatttatata
     9781 taatttacac tcaattatac ataatttatt tataagttta ttctactttt ttatatccaa
     9841 attcttcaaa aatcttttgc ccttcctcac ttagtaaaaa ttcttcaaat ttcttagcag
     9901 catctacatt tttactagct ttaattaccg aaactggata tgtaataggt gaatgagttt
     9961 tttcgtctgt tttttcaact acttttatct tatcattatt gacagtatca ctgaagtaaa
    10021 cgaatccaac atcagcattt cctgattgta cccatgctaa aacttctttt acatcttttg
    10081 caaatactag cttatctttt aacttatctt ttaaatttaa attagttaac acctcatctg
    10141 catacttacc agctggaaca ctttcagctt caccaacagc aattttctta actttatctg
    10201 tagtcaaatc tttcatacca gttacattac tgtcagcaga agaaataaga actaaatcat
    10261 tttttactaa atctttcata gtatcagaaa ctaataactt ctcttcatcc aaagctttca
    10321 tttgtttttg acctgctgaa ataaataaat cacaaggtgc tccttgctct atttgttgtt
    10381 gtaatgagcc tgatgctcca tagttaactg taagctttac atttgaatca atttttttat
    10441 attcttcttc aatctttgcc attgcttctt ttaaacttgc agccgccgat acatttaact
    10501 ctattgaatc actactttta tttgtttttt cttgttttcc atcatccttt ttgctttcat
    10561 tactattgca tccaactgtc cccaaagtta aacatgcaac tagtcctaat attcccaata
    10621 tttttttcat accaatctcc ctttttgtaa atttaataca tattttaaca tgttttatta
    10681 tgttttatca tgttttgtca tgtatagttt aattatatat acctgataat aaattttcaa
    10741 gtaatttatt tacattactt ttaaatattt tgctacattt tccttttttt aatgttaaaa
    10801 taaccttata tggaggtgga ttatggactc attatcatct ttgacacctg tcgaggtagc
    10861 tgaattatta aaaataacaa aaaatactgt ctatgaatta atcaaaagag gtgaacttcc
    10921 ttcttataaa gtagggaaaa aaataagagt tgatattaaa gatgttgaag aatatatcaa
    10981 catacaaaaa actggtaaag taaaagatac acattttaac aataaaaata tagatataaa
    11041 taataatttt aaaattatta tctctggtca agatgtaata ttagacattt tagctaggtc
    11101 tgttgaaaaa aaattggatg gaataagtac atttcgctct tatataggta gttataatgc
    11161 tttgtatgag ttatataatg gcagagtttc catagcatca tcccatctat gggatttcga
    11221 aacggatgaa tataatagca cttttgttaa aaaactattg ccagggatac catgtgtact
    11281 tataaatcta gcttatcgaa tgcaaggttt ctatgttgct aaaggaaatc ctaaagaaat
    11341 aaaaacctgg gatgatttaa caaaatcaaa cataaccatt gtaaatagag aaaaaggttc
    11401 tggaactagg gttctactag atggtaagct taggcttcta aactttaatg gtaaacatat
    11461 aaaaggttat gataatgaag agttatcaca tcttggagtt gcaagtactg tttctcgtgg
    11521 aatagctgat gttggtttgg gaaatgaaaa agctgcttta caagtaaata atatcgactt
    11581 tattcctctt cacaaggagc gttatgattt agttattaaa aaagaggact tacaaaatcc
    11641 agtttaccaa actataatta acataataaa ctctcctgag tttaaagctg aacttcaagg
    11701 cattggtgga tatgatttaa ccgatactgg aaaaactata gcaaaagttt aaaattaaaa
    11761 tcgcaatcta ttttataaga tttataattt ttcacaaaat ttataactta aacacgaaat
    11821 aaattgcgat ttttagtatc tcaaaaaatt tatatctttc attttatcat ctaatataaa
    11881 atttaatata attaattgtg taagtatatt atattaatat atatttacat aatagtattt
    11941 ttccttaata tagattaaca tatgatatgt tttagacatc aatccctttc ctttcttata
    12001 tatatatggt aacacatatg agtttaatag attatataca atattgcttt cttcttgtat
    12061 tttttcaact aacaagttat ttataaaatt atctttttcg ctctcaataa tatcactcca
    12121 atttatctta acttttaata tatatcttcc cactaggtat acacactcta caataaataa
    12181 taaaaataca atacagtcag cacctgttgt cttatataaa tttcccgata ctaatggctt
    12241 agcgaagaaa ttataaaaat tcaaagtatc tcctgtataa tcaaaaagta ttagtagtag
    12301 tcctaggact ctcaatacct taatattaaa catattttta tctttattat ttttattttt
    12361 catatatact acctctcttt tctttagatt ttattgtaat ctaatactaa ctcttttatt
    12421 tgaggtataa atgaatttaa ttggtaatta ttttcatttt tactagaaat taattcacat
    12481 taataaagaa aacttatatt taaacataaa aatagcctat ctatttttaa taaatacaaa
    12541 aataaataag ctactaatat tcaactaact tttatcactt aaaacattac tatctataaa
    12601 tttaaatatt ttattgaagt atactgtact atcatgctca aatccatcaa catgaccaat
    12661 accttctata aaccatagtt cttttttatc atgtttaact aaatcataca tttttttact
    12721 attttgataa ttacaaacag tatcttttgt cccatgtata aacagtatag gtacattaga
    12781 tttctcgact gactcatatg gctttacatc actgtaccaa aatccagatt taaacttatt
    12841 atataaatct ccacaagtta ctacataatc gattaatata cctggtattc gtttttctag
    12901 tactcccatt ctaattgcat ctttcatttc agaatacgga gaatccaata tataaaaatc
    12961 gaccttctca ttttttgaat ttatctctgt atgcatagca gctgttcctg cccccatgga
    13021 aaatccatgc actcctaatc ttccttcagg aaatttattt tttacaaatt taactagact
    13081 atctaaatca tacctttcat aaagaccaaa tgtgtaatta tctccgccac tattacctgt
    13141 atttctttga ttataaacta atacattata acctttatct aaatatccat atgctacctt
    13201 taacatttca tagtaactac ttccaattcc atgaacaagt ataatagtat ctcttgtctt
    13261 tatatttgaa gttatgaaaa gactttcaag cttgtaatta ttagaacttt gtatcattaa
    13321 ttcagctgtc ttgtagtttt ttaatttatc cagtggttta tcttttctct cagaaaatat
    13381 ttttactata tcttcgtttt ttattaattg ctctaagcca actgaactat tgtacactaa
    13441 tttgccaaat atataagata gaattaatag gattaataga aacacaattg atataattat
    13501 aaatttattt cttaaactaa tataattttt aaaactattt ttcatattta tttaccatgc
    13561 aattttccta tattatattt tttaagta
//
LOCUS       DBGJFK010000093        13093 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.095, whole genome shotgun sequence.
ACCESSION   DBGJFK010000093 DBGJFK010000000
VERSION     DBGJFK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13093
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.095"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            456..734
                     /locus_tag="ACOIAP_003236"
     CDS             456..734
                     /locus_tag="ACOIAP_003236"
                     /inference="COORDINATES: protein motif:HMM:NF023166.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HGZ2640111.1"
                     /translation="MFFKDSRYIRVISDNIKEQMRNYIKKDNTKSYFIDQDKGSLVKE
                     FECINKCQDFYFNRNGNLVISFGKYELAPGYMRAVEFVIPNEVIKSLR"
     gene            776..1597
                     /gene="xdhC"
                     /locus_tag="ACOIAP_003237"
     CDS             776..1597
                     /gene="xdhC"
                     /locus_tag="ACOIAP_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0009115 - xanthine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0065003 - protein-containing complex
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory protein XdhC"
                     /protein_id="HGZ2640112.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVIVLDSFEEIPDFPTDENSYIIILTRGHLYDSSALEWALKRDAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSRVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            1602..2363
                     /locus_tag="ACOIAP_003238"
     CDS             1602..2363
                     /locus_tag="ACOIAP_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HGZ2640113.1"
                     /translation="MNIGSKDSDILNVNFRGIDIKVILVYKNRKNISIKIDPFGKVIV
                     MSPPKMSKKIIKDIIIEKGDWILKKSEKYKGREEVYEQRMFITGEKFLYLGEEYHLVI
                     KEMLKDSVKKSNCKITINEYEIIVQTNDTSTDFIKKSLKSWYKIESERLVLERIDFLK
                     LNYEIMNQLVPASVKVKEQKKRWGSCTSQKNIYINSKISMAKLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKITI"
     misc_binding    2524..2780
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2893..3132
                     /locus_tag="ACOIAP_003239"
     CDS             2893..3132
                     /locus_tag="ACOIAP_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGZ2640114.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMKH"
     gene            3360..4406
                     /gene="ilvC"
                     /locus_tag="ACOIAP_003240"
     CDS             3360..4406
                     /gene="ilvC"
                     /locus_tag="ACOIAP_003240"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGZ2640115.1"
                     /translation="MSNKNKYHKNKKKYWEEMKMARMYYEKDVDLEVLKNKKVAVLGY
                     GSQGHAHAQNLRDNGVYVVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLIMMLMPD
                     EKQKKVYEESVKDNLKEGQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVF
                     TKGSGVPALFAVYQDYTKKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVL
                     CGGISELIKLGYKTLVDAGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEY
                     GDYVSGKRVITDAAKQGMQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIA
                     EVGRNLRSMMSFLK"
     gene            4459..6147
                     /gene="ilvB"
                     /locus_tag="ACOIAP_003241"
     CDS             4459..6147
                     /gene="ilvB"
                     /locus_tag="ACOIAP_003241"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HGZ2640116.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFKVANSGRKGPVLVDVP
                     KDLFLAEMDFSDEDYDLCQIDDYIDYKSDFSLDDEINVKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEDILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLIGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGIQTDEFHPQSILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGAKVGNIDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNERYSQTDINENVDYVKLVNAY
                     KIDGYKISNMEELGKVLDVIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            6355..7032
                     /locus_tag="ACOIAP_003242"
     CDS             6355..7032
                     /locus_tag="ACOIAP_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HGZ2640117.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDVNPPS
                     FEKPLKK"
     gene            7202..9238
                     /locus_tag="ACOIAP_003243"
     CDS             7202..9238
                     /locus_tag="ACOIAP_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HGZ2640118.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNEEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITNKELYKEIAMKTIDYVVREMQDKDGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIDNLSKKV
                     FEYRKERTSLHKDDKILTSWNALMVVALTKAYSTLKNDMYLDYSNKCLDFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCIDLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNKLEEMSYKQ
                     LKLYVNNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLSAFKELISENFIPNTT
                     FLAKKYNEENTIIGFLNNYKLKEDKTSYYVCQSNSCSQPINNLQKLKDMILGVE"
     gene            complement(9556..9864)
                     /locus_tag="ACOIAP_003244"
     CDS             complement(9556..9864)
                     /locus_tag="ACOIAP_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGZ2640119.1"
                     /translation="MTILSTLHLSEEETTLNNIARKMVTSKQNINRIVVNLKKNGYID
                     VITSPHDKRAITVKVIDLGKEVMVTCGRAVINLMADVFHEFIKDELETLWNLLKNVLF
                     "
     gene            10274..11209
                     /locus_tag="ACOIAP_003245"
     CDS             10274..11209
                     /locus_tag="ACOIAP_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase"
                     /protein_id="HGZ2640120.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKNPKAVVQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGRQGIILNLAHMIINREI
                     KKYGRRSRSNKINDLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLIQGLKEIEDKENLKKVPLDVPIYIISGDKDPIGKNSKGVLRLRDRYIKLGVKDVT
                     CKLYKGGRHELLNEINKEEVFEDVICWLNNKIGIL"
     gene            11573..12340
                     /locus_tag="ACOIAP_003246"
     CDS             11573..12340
                     /locus_tag="ACOIAP_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640121.1"
                     /translation="MSKILRVKNIKKYYKSRGNITKAIDNISFEVESGEYIGIMGASG
                     SGKTTLLNCISTIDKTTDGNIYIGNKDITTMNEDELSKFRREELGFIFQDFNLLDTLT
                     AHDNIALSLSINGVNSKEIDNKIKKIANKLGVYEILNKYPYEMSGGQKQRIACARAII
                     TNPSLILADEPTGALDSKSAKLFLENLEVLNRELKATILMVTHDAFTASYCKRILFIK
                     DGKIFNELVRGNNTRQEFFDRIIKVISVLGGDDKHVF"
     gene            12330..>13093
                     /locus_tag="ACOIAP_003247"
     CDS             12330..>13093
                     /locus_tag="ACOIAP_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGZ2640122.1"
                     /translation="MFFKKNKSRRSRNKRKNNYVSRVSSESFKKLALNNVKKSLKNYL
                     IYFITLVFGVIILYTFNSLDNDIAILSSNALLSSSISFVRGIVSIFSILVCIIFAFLI
                     IYANNYLMKQRKKEFGIYSILGMDRRDINKLMFREMMIIGIFSLIIGIIFGVFVSKGL
                     SIFALKMLGISSSGFSFSMLTTIKTIVFFGIVLLLVNKFNKKTIKKYKLIDLLNANKK
                     NEVSVAKGKKSNLILFFLSIVAIVLAYIIPLKMKIST"
BASE COUNT         5299 a         1277 c         2266 g         4251 t
ORIGIN      
        1 aacttaaaaa atctatattt aaaattgcta tagtttcaat atgtttatta gtatcattag
       61 taattacaaa ccctatattt tcagataatt tttctaatga gacttaaact agtgatatga
      121 taaaggtgtt acatgctaag agtttcaact ttaaacaaga caattatgaa gtgaaggtta
      181 gtattcctaa aataaaaggt ttaaaagata aaaatttaga gattaaatta aataatgaat
      241 ttttataata tgggataaaa atttacagtg aacttcaaaa taaaataaaa aaataataag
      301 gggtatagat acctaaatgt aagctataat gtcaagaata attctgagga ctttttatca
      361 atagaaatga caaaagaata gatagaagcc tcctcatctg taactaagaa gcattacact
      421 atcaataaaa atagagaaat actattaatt taccaatatt ttttaaagat agtagatata
      481 ttagagttat aagtgataat ataaaagaac agatgagaaa ttacattaag aaagataata
      541 caaaatctta ttttatagac caagataaag gttccctagt gaaagagttt gaatgtataa
      601 ataagtgtca agatttttat tttaatagaa atggaaatct tgtaattagt tttggtaaat
      661 atgaattagc gcctggttat atgagagcag tagaatttgt gataccaaat gaagtaataa
      721 aaagcctaag atagatatat agaagatttt tagatagact ggtaaggaga attatatgaa
      781 tatatatgaa caagcaataa gattaataga aaataatgag gattttgcat ttgctacaat
      841 aacttctcat tcaggttcaa caccacgtga aactggagca atgatgattg taaaaaatga
      901 ttctactata tttggttcag tgggaggagg tagtgtagaa gcagaatgta taaaacatgc
      961 aattaatgtt ataaaaaata gagaatcgat gctgtataaa tttactctaa acaaatctga
     1021 tgtggcaaaa ctaggaatga tatgtggggg tactggagaa atacaaatag attttataga
     1081 tagtaaatta aaaagtaata tagaaaaatt caataagaga ctaaaggaaa atacgagtaa
     1141 agcgtatata tttggagcag gtcatatttc aagagatgtt gctgtgatac tatctctttt
     1201 agaatttaga acagtagtaa tagatgatag agaagaattt gctaatcatg aaaggttccc
     1261 agaatcagaa gtaatagttt tagattcttt tgaagagata ccagattttc caactgatga
     1321 aaatagctat ataattattt taacaagagg tcatttatat gattcaagtg ctttagaatg
     1381 ggctcttaaa agagatgctg gttatatagg tatgattgga agtagaacaa aaattggatt
     1441 gacgtacgaa aaactcatga aaaaaggttt taagaaggaa gaattatcaa gagtacatgc
     1501 accaataggc ataaaattga atgctcaaac accagctgaa atagctgtat gtatagctgc
     1561 tgagcttata aactgtagag ctaataagga aaaataaact aatgaacata ggaagcaaag
     1621 atagtgatat tttaaatgtt aattttagag ggattgatat aaaagtaatt ttagtatata
     1681 aaaatagaaa aaatatttct ataaaaatag atccatttgg aaaagtaatt gtgatgagcc
     1741 ctcctaaaat gtctaaaaaa ataataaaag atataatcat tgaaaaagga gactggatac
     1801 ttaaaaagtc agaaaagtat aaaggaagag aagaagtata cgaacaaaga atgtttataa
     1861 ctggcgaaaa atttctttat ttaggtgaag agtaccatct agttataaaa gaaatgttga
     1921 aagattctgt taaaaaaagt aactgtaaaa taactattaa cgaatatgaa ataatcgttc
     1981 agacaaatga tacaagtact gattttatta aaaaatcttt aaagtcttgg tataagatag
     2041 aaagtgaaag attagtgtta gagagaatag attttcttaa attaaattat gaaataatga
     2101 atcaattagt tccagcaagt gttaaggtaa aagaacaaaa aaagagatgg ggaagttgca
     2161 catctcaaaa aaatatttat ataaactcaa aaatatctat ggcaaaatta gatgtaattg
     2221 attatgtaat aatacatgag tttagccatt tagtacatat gaatcactct aaaaaattct
     2281 atgatttagt aaaatctatt atgccagatt ataaagacaa agaaaattgg ttaaaaataa
     2341 atggatataa aataacaatc tgaaaacggt tattccaaaa cataggtgta aaatgtaaga
     2401 gaagtattat tgtgaaaaaa ataaataatc tgaaaatttt aaaaaaagtc gttgacattg
     2461 taaatgatag ggaatataat ctatattaac aacaaaacag aactgaaata taaaattaaa
     2521 aaattaaaag caatgacaga gacaacaata ctaatagtgt tatccacaga gaaccaatgt
     2581 tgctgagaat tggtgttaac ggtagtataa tgatcactct ggagcttttg tactgaatat
     2641 ttttagtaag tacaaacgtc tgtcaacgtt acatgactaa ggttaaggta attaattatc
     2701 cgacctgaaa aaagaggggt agatgtattt ttatatctac aaataaggtg gtaccgcgga
     2761 ataaaacttt cgtccttata agtaatattt atattgctta taaagatgaa agttttttta
     2821 ttttaagtga tataaataaa tttaatccat ataaaattaa taaaaaaata ataaaaacaa
     2881 ggaggaattt ttatggaaaa tactgtatat gctaaattaa accaaggaat agattctttt
     2941 ttaagagtgg ctatgactct aagaagaaga gaagttgata tacaatcaat aagcatgact
     3001 gtagataata tgaataactc aggtataaaa ttaatagtaa atgaagaaaa gacatcttta
     3061 gattctgtct taaaccacat gaaaaaacta catgatataa gagagataac tgttgaaaga
     3121 atgaaacatt aattaaatat atttttataa agctaaagat aaatatgctt attttaaaat
     3181 aaaaaactaa agataaatat taaataagaa aaatcttaga ttaaagtaca agtatcattg
     3241 aatttgtcag tttatcatat ctgataaaaa ctgaaaattc taaaaatata attgtaaaac
     3301 tatataaatt tagaatttaa atctgttgaa taatattaaa ataatgataa tgagtatgaa
     3361 tttctaataa aaataaatat cataaaaata agaaaaagta ttgggaggaa atgaaaatgg
     3421 caagaatgta ttatgaaaaa gatgtggatt tagaggtttt aaaaaataaa aaggttgcag
     3481 ttttaggtta tggaagccaa ggacatgcac atgcacaaaa tcttagagat aatggtgtat
     3541 atgtagtgat aggtctttat gacggaagta aatcagcaca aaaagcaaaa gaagatggat
     3601 ttgaagttaa gagtgtagca gaagctacaa aagaaagtga tttgataatg atgttaatgc
     3661 ctgatgaaaa acaaaagaaa gtttatgaag agagtgtaaa ggataactta aaagaaggtc
     3721 agacattagc ttttgctcat ggattcaata tacattataa ccaagtacaa ccaccagaat
     3781 ttgttgatgt tgtaatggta gctcctaaag gacctggtca cttagttaga aatgtattta
     3841 caaagggaag tggagttcct gcactatttg cagtatatca agactacact aaaaaagcta
     3901 cagagacagt tttagcatat gcaaagggga taggagcaac aagagcaggt gttttagaaa
     3961 ctacttttaa agaagaaaca gaaacagatt tatttggaga acaatcagta ctttgtggtg
     4021 gaataagtga acttataaaa ttgggatata aaacgcttgt agatgcaggt tatcaaaaag
     4081 aagtagcata ctttgaatgt ttacatgaaa tgaaactaat agtcgacctt atatatgaag
     4141 gtggatttga aagaatgaga tatagcataa gtgacacagc agaatatgga gattatgtat
     4201 ctggtaaaag ggtaataact gatgccgcaa aacaaggtat gcaaaatgtt ttagaggata
     4261 tacaaaatgg aaaatttgca aaagcgtgga ttaaagagaa tgaagaagga cgtgagaact
     4321 tcctaaaaac tagagaagaa gaatataata cagaaattgc cgaagttggt agaaatctaa
     4381 gaagtatgat gtcattctta aaataaatat atattaaatg gattagtttg agggaaagag
     4441 tggtgtatag tagtgcgtat gaatggagca aaggtaattt tagaatgttt aaagaaagag
     4501 ggcattgaca caatatttgg atatcctggt ggagcagtaa tacctcttta tgatgctcta
     4561 tacgattatt cagatgattt taaacatata aggacatctc atgaacaagg tttagttcat
     4621 gccgcagatg ggtacgcaag aagtactaat acagtaggag tttgttttac aacgtctggt
     4681 ccaggagcaa caaatgccat aactggaata gcaacagctt ttatggattc ttcacctatg
     4741 gttgtaatct caggtcaggt tccaacaagc ttattaggta aagattcttt tcaagaaatt
     4801 gacataactg gagcaacatt atctatgaca aaacataatt atttagttag aaacactaaa
     4861 gaattagttc ctacaataaa agaagctttt aaagttgcaa attcaggtag aaaaggacct
     4921 gtacttgtag atgttccaaa ggatttattt ttagcagaaa tggattttag tgatgaagat
     4981 tatgatttat gtcaaataga tgattatata gattataaga gtgattttag tttagatgat
     5041 gaaattaatg tcaagctttt aaatgaagca atagatatca taaaagaatc taaaaagcct
     5101 gtaatatatg ctggtggagg agttaagtct tcagatagcg aggatattct tgaaaaattt
     5161 gcaactaaga tagatacacc tgtactaaat acacttatgg gtcttggtaa tatagataga
     5221 aaaaatgaac tatctcttgg aatggttgga atgcatggaa gtagagaaag taatttagcc
     5281 ctttctaatt cagatttagt gatagcgata ggtgctagat ttagtgatag agtaataagt
     5341 aaaagctctg aatttgctaa aaatgcaaaa ataatacaca tagatataga cccatctgaa
     5401 ataagtaaaa atatagaatc taatgtatct ttgattggag atgtaaagtt agtccttagc
     5461 ttactaattg aaagggtcga aagtaagaat aatagcaatt ggaaagaaga gataaagaca
     5521 tttagaaaga gtgagggtat acaaacggat gaatttcatc cacaaagtat acttaaaaaa
     5581 ataaatgaga aatatgaaac attaaagaag cctactgtgg tagtaactga tgttggtcaa
     5641 catcaaatgt gggctgctaa atactggaat tttaaaggaa ataaaagttt tataacatca
     5701 gcaggattag gaactatggg atttggttta ggtgcagcta ttggagctaa agttggtaat
     5761 attgataaaa atgtggtttt agtaactggt gatggaagtt ttagaatgaa ctgtaatgaa
     5821 ctagctacag ttgcaaatta taatgtacct atgcttattt tactactcaa taatagaacc
     5881 ttaggaatgg taagacaatg gcagaagtta ttttccaatg aaagatactc tcaaactgat
     5941 attaatgaaa atgtggatta tgttaaactc gtaaatgcat ataagattga tggatataag
     6001 atatccaata tggaagaatt aggaaaggta ctagatgtga tagattttaa taaacctgtg
     6061 tttttacaat gtgatataga taaggattat gatgtttatc ctattgtagc acctaatgat
     6121 gcattagaaa atttgatatg taactaaaac ttatactgaa tattgataaa attttttatt
     6181 aaacttttat tgatattcag tttttattta gagatagagt ggtatttttt atttttgtag
     6241 ataaaaaaat gaatatataa ttaagaattt atcaaatttt aattatacaa tttagaataa
     6301 tattacaact taagtaaata ataattttga ataataattt acggaggtat tcatatgttt
     6361 aaacacgata aagcattatt aaaagaagta aaagtagaaa gaccaaatcc tcaatatgct
     6421 gttttaatgc aagaacagtt gggtggtgca aatggagagt taaaagcagc aatgcaatac
     6481 ttgtcacaaa gttttagaat aaaagaccct caaataaaag atttatttct tgatatagca
     6541 gcagaagagc ttagccatat ggaaatggta gcacaaacta taaatttatt aaatggacat
     6601 gatgttgatt ataatgcagt taatacaggc gaaatagaaa cacatgtatt aactggtttg
     6661 tcaccagttt taataaactc atcaggagct ccttggactg ctaattatgt tacagttaca
     6721 ggggatttag tagctgactt attatcaaat atagcttctg aacaaagagc taaggttgtt
     6781 tatgagtact tgtatagaca aatagatgat aaatatgtaa aagaaacaat agatttctta
     6841 cttaatagag aagaagcaca taatgctcta tttagagatg ctttaaataa agttaaagat
     6901 acaggttcaa atagagattt tggagttaca gaagattcta agttatattt cgatttatct
     6961 actccagggc caaatcatga tactaagata gatgttaatc ctccttcttt tgaaaaacct
     7021 ttaaaaaaat aattttatat tttttatgtt attttagtag tcataagaaa ttatttacta
     7081 gaagagttta ttagataaaa aattaaatat gtatagttaa aaatgggtat acacttacta
     7141 taagtgtata tctatttgtt tattgcaaaa catataataa aataacaaat gaggtggtat
     7201 tttggacagt aatagaaaac ctaataatct aataaatgaa aaatctccat atcttttaca
     7261 gcatgcatat aatcctataa actggtatag ttggaatgaa gaggctttta aaaaagcaaa
     7321 agaagaggat aaaccaatat ttttaagtgt aggatattca acatgtcatt ggtgtcatgt
     7381 tatggaaaaa gaatcttttg aagatgaaga agttgctgaa ataatgaata gaaattttgt
     7441 tgcaataaaa gtagataaag aggaaagacc tgatgtagat agtgtgtata tgacagtttg
     7501 ccaagctatg acaggtagtg gtggatggcc aatgactata ataatgacgc cagataaaaa
     7561 accttttttt gcaggaacat acttcccaaa atattcaagg tataatagac ctggagttat
     7621 agatttatta gagaatgtat ctgaaaaatg gaatacaagt agagatatac taataaaatc
     7681 tggagatgaa ataatagaag ctcttaagga tgattttggt gtaaaaaata ctgaaggtga
     7741 tttatcaaaa gagatgttaa gttcatcagt tagagtattt aaggctattt atgatgaaaa
     7801 gtatggtggt tttggtaatg cccctaaatt tccaagtcct cagaatctta tgtttttgat
     7861 gaaatactat agtatagaaa aagataaaga tgtattaaaa atggtagaaa aaactttaga
     7921 tggtatgtat agaggaggat tgtttgatca tattggattt gggttttcaa gatactctac
     7981 tgataaaaag tggttggctc ctcattttga aaaaatgcta tatgataatg ctatgcttac
     8041 tatagctttt ctagatgcgt ataaaataac aaataaagag ttatataaag aaattgctat
     8101 gaaaactata gattatgtgg ttagagagat gcaggataaa gatggtgggt tttattcagc
     8161 gcaggatgct gatagtgaag gtgaagaagg taaattttat acatttaatc ctcttgagat
     8221 aattgaagtg ttgggtgaag aagatggaac tttctttaat aattattttg atataactag
     8281 tagtggaaac tttgagggca aaagtattcc taatcttata aaaaataaag aatatgagag
     8341 acataatgaa aagatagata accttagtaa aaaggtattt gaatatagaa aagaaagaac
     8401 atctttgcat aaagatgaca agatacttac atcatggaat gcattgatgg tagttgcttt
     8461 aacaaaggca tatagtactt taaaaaatga tatgtattta gattattcaa ataagtgcct
     8521 tgattttata aataataatc ttgtaaatga gtcaggtaga ttgttagcta gatatagaga
     8581 tggaagttcc gactatttag catatttaga tgattatgct tttttaatct gggcgtatat
     8641 agagctttat gagtcaacat ttaatatgaa atatttggaa aaggctttaa atttaaatga
     8701 aagctgtatc gatctttttt gggattatga aaaaagtgga ttttatatat atggtaaaga
     8761 tagtgaaaat ttaatagcaa gaccaaaaga tttgtatgat ggagctattc catcaggaaa
     8821 ctctgttcaa ttatacaatc ttataagact tgcgaaaatt actggcgata ataaacttga
     8881 agaaatgtca tataaacaat taaaactgta tgtgaataat gtaaagagtt ctccaactgg
     8941 ctacagcttt tatatgcttt cattgatgtt tgaactttat tctactaagg aaattatatg
     9001 tatttttaag gaagattccg atttaagtgc atttaaagaa ttgataagtg aaaattttat
     9061 accaaataca acttttttag caaagaaata caatgaagaa aatactatta taggtttttt
     9121 aaataactat aaattaaagg aagataagac tagttattat gtgtgtcaaa gtaatagttg
     9181 tagccaacca attaataatt tacaaaaatt aaaagatatg attttaggag tagaataacc
     9241 agaatagtga aaaaggagat gtcttaaagt aaaaatctaa tcatctcctt tttttgtaca
     9301 aaaaacaaaa aatagtttct aagaacactt aatctatgta ataattgttt tgttaaaaga
     9361 tgaaaatgat attatagtta tataaaatat tgcattataa aaaagtggta ttattataga
     9421 tgttatagta ttaatcgttt ttatttacct atttcttatt tttacaaatt cttcaagtgc
     9481 ttcagattta attttattta tttcttcata ttcccaaaat tagcaccttc tttaaagccg
     9541 tcttgttctt cattattaaa acaatacatt ttttagtaaa ttccacaagg tttccaattc
     9601 atctttgata aattcatgaa atacatctgc cattaagttt attacagctc taccacatgt
     9661 taccataact tcttttccta agtctataac tttaacagta attgctctct tatcatgagg
     9721 acttgtaatt acatcaatat atccattttt tttaagatta acaactatcc tatttatatt
     9781 ttgtttactt gtgaccattt ttcttgcaat attatttaat gttgtttctt cttctgataa
     9841 atgaagagta gataaaatag tcatatactg tcttgaagta agtataccaa aatatttata
     9901 tccttctatt tgtattttgt ttgtaatggt aaaaaagttg catatgtttg attcattaaa
     9961 aagagttctt ttagttaatt tgaataatct attaaatatc tactttatct ttagatgttg
    10021 ttttgtcgaa aataaaatat catgaattaa ttctaatgtc aatatggtat caaaatatat
    10081 taaagtatta cttttttatg caaatattaa ttaaattatt atataatttt atgtaataat
    10141 ttctatacac aatgataact tctatgaagc attaataatt cttaaatttt tttagaaaga
    10201 ttttgacttg aaaacacttg taatataata tataaattaa tatactgaat aaaatcaatc
    10261 tggagggata attatgaagt gtacaaactt tactttcaaa ggagaggaag gtttagatat
    10321 atatacatat aaatgggaag atgaaaatat aaaaaatcca aaggctgttg tccaaattgc
    10381 gcatggaatg gctgaaactg cacaaaggta tgagactttt gccaaggtgc ttactaaaaa
    10441 tggttatata gtatatatca atgaccatag aggtcatgga aaaactgcaa agataataga
    10501 aaatgttggg catttagctg agaaagaagg ttttagatgt cttgtagagg acatgtatac
    10561 tttaacaaat attataaaga aagaaaatga agatttgcca atttatctat ttggtcatag
    10621 catgggttca tttgcaagtc aaagatatat aatggattat agcaataatt tatctggtct
    10681 tatactatgt ggttcaaatg gaaggcaagg aatcattcta aatcttgctc atatgataat
    10741 caatcgtgag attaaaaagt atggaagacg ttctagaagt aataaaataa atgatttgat
    10801 ttttggtggc gaaataataa gaagaaatga gaagactaag tttgattggt taagtagaga
    10861 taaagaacaa gttgagaaat atatcaatga cccattttgt ggagtggtgt gtagttgtgg
    10921 ctttttttat gatttaattc aagggttaaa agaaattgag gataaagaaa acttaaaaaa
    10981 agtgccactt gatgtaccta tttacataat atctggagat aaagacccta tagggaaaaa
    11041 tagtaagggc gtcttaagac taagggatag atatataaag ttaggagtaa aagatgtaac
    11101 ttgcaaactt tacaaaggtg gaagacatga attattaaat gagataaata aagaagaagt
    11161 ttttgaggat gtaatttgtt ggctaaacaa taaaatagga atattgtgat aaaggaatat
    11221 tatattaata ttaaatttaa ttctatgtaa atgtttgaaa agtatattta atatgtgtaa
    11281 aacagaaaag aaagtgtttc aagatgatta tttattatca atgaaacacc tttttatttt
    11341 ttgataaata tatttaccac tttcaagaga agagtgtttc aaaatcttaa gaaaatcttt
    11401 tgatttaagt atatgttttc ttaagaaaat taaattattc tattaaaaga actagaaata
    11461 agtaagtgat tttggttttg ataaatataa gaatctttat ttattaagtg cgtaaaaaat
    11521 ataaatttat ttggttttaa ttccaaagta aaacttaatg gaggtaatag atatgagcaa
    11581 aatattaaga gtaaaaaata taaaaaaata ctataaaagt agaggtaaca ttacaaaagc
    11641 tattgataat attagctttg aagttgaaag tggagagtat ataggtatta tgggagcttc
    11701 aggaagtgga aaaactactt tactgaattg tatttctact atagataaaa cgacagatgg
    11761 gaatatatat ataggaaata aagatataac aactatgaat gaagatgagt tatctaaatt
    11821 tcgtagagaa gaactaggtt ttatatttca agattttaat ttattggaca cacttacagc
    11881 acatgataat atagcattgt ctttatctat caatggagtc aattcaaaag aaatagataa
    11941 taaaataaaa aaaatagcaa ataaattagg tgtttatgaa atacttaata agtatccata
    12001 tgaaatgtct ggtggtcaaa agcaaagaat agcatgtgca agagctataa taacaaatcc
    12061 atcactaata ctagcagatg aacctacagg agctctagac tctaagtcag caaagttatt
    12121 tttggaaaac cttgaagttt taaatcgtga attaaaagct accatattaa tggttacaca
    12181 tgatgctttt acagctagtt attgtaaaag aatattattt ataaaagatg gtaaaatatt
    12241 caatgagttg gttagaggga ataatactcg tcaagaattt tttgatagaa taataaaagt
    12301 aatatcagtt cttgggggtg atgataaaca tgttttttaa aaaaaataaa tcaagaaggt
    12361 ctagaaataa aagaaaaaat aattatgttt caagagtgtc aagtgaatca tttaaaaaat
    12421 tagctttaaa taatgtgaaa aagagtctaa aaaattattt gatttatttt ataacccttg
    12481 tatttggtgt tattatttta tacactttta attctttaga caatgatata gcaattctta
    12541 gtagtaatgc tttattgagt tcaagtatat cgtttgttag gggtattgta agtatttttt
    12601 caattctagt ttgtattata tttgcatttt tgattattta tgcaaataac tatttaatga
    12661 aacaacgtaa aaaagagttt ggaatataca gtattcttgg aatggataga agagatataa
    12721 ataaattaat gtttagagaa atgatgataa taggcatatt ttcattaata ataggtatta
    12781 tatttggagt atttgtttct aagggactta gtatatttgc cttaaagatg ttgggcatat
    12841 catcatcagg attttctttc tcaatgctta caactattaa aacaatagta ttttttggca
    12901 ttgtactgtt attagtcaat aaattcaata aaaaaacaat aaaaaaatac aagttaatag
    12961 acttattaaa tgcaaataaa aagaatgaag tttcagttgc aaaaggaaaa aaatctaatt
    13021 tgatattatt ctttttatct atagtggcaa ttgttttagc atatataata ccattgaaaa
    13081 tgaaaatatc tac
//
LOCUS       DBGJFK010000094        12952 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.096, whole genome shotgun sequence.
ACCESSION   DBGJFK010000094 DBGJFK010000000
VERSION     DBGJFK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12952
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.096"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(187..723)
                     /locus_tag="ACOIAP_003248"
     CDS             complement(187..723)
                     /locus_tag="ACOIAP_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HGZ2640123.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRIMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEIDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDVEEEN"
     gene            complement(741..2054)
                     /locus_tag="ACOIAP_003249"
     CDS             complement(741..2054)
                     /locus_tag="ACOIAP_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HGZ2640124.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEENIEDIEPYWVCLPMATRTAV
                     GSYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRASESLQRYCSIVNKQYGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGIAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVRLPYGHTWKSFTYFLLDTLPENIRNNYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2389..2829
                     /locus_tag="ACOIAP_003250"
     CDS             2389..2829
                     /locus_tag="ACOIAP_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HGZ2640125.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKNGYARLCKLETYLETQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVMIQIGDKQVPAVEKMLISLTPKA
                     KEHWVTRYPCGNNGGWIRCRILEDADLLDIIQYIRAKKAPPKQN"
     gene            complement(2999..3187)
                     /locus_tag="ACOIAP_003251"
     CDS             complement(2999..3187)
                     /locus_tag="ACOIAP_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640126.1"
                     /translation="MNKNDNLVIICMFIGMILGVAIGYVMGIYKGSVGTTMCYGLVFG
                     MLIGICIGAVIKNSNKKE"
     gene            complement(4085..9295)
                     /locus_tag="ACOIAP_003252"
     CDS             complement(4085..9295)
                     /locus_tag="ACOIAP_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HGZ2640127.1"
                     /translation="MANKLYSGIVNLLEDGRDELRKYNLEKKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDAETGQVYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRYTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKALISNVTEEKIRNILNKTKEDLDGQEIDYDGCKELIYL
                     LDVMLSDSVSIELCNPLDKNPEKLLDKMKNLPETFEKTNLGLMLTASCKIEIQKAVDV
                     TYKELEKLLVPYIESVKKGMEDSISTLSSINSLKDKKIQLDRMYTDLCGRANSMKELM
                     EFVQELSYGDGMQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYKEEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLIK
                     IISGYKLDILSSIYMYGDCELKIDCSMEKDVFSGKNIVLLTEKVFIPEGSYSINVSGK
                     NAEKLAGEDYIYNGMNGRNGNNAGTSGDIILSFKEIEKIGELKLYVDGGRGGNGQDGK
                     IGETGLTGKAGENAKIGSKKESKEFAKDKDTKYYLVKAEKGKQGGTGGIGGNGGNAGL
                     GSKAGQVYLLGKATLLKGAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GISAPIDDSDRNYYYFDRYVFNHASDEKEVADDGVKLNALYEKHKDWTISKREDSGSV
                     GAEGKDGLSGDTLKEKELLKQEHSLSIDTFFYEFFERFGFSGSKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYGFEKKNKAVLSLDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFIGEKQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKILKELEEGKKDELKEGYFNTYKESILTQIESGNQQIAVLKNELENK
                     MLSVNAKMNLLIQEIIKIKEDEKEDIEKLKEKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEGKRDKFDQIKEIIVKSIDDDNYSDKDDDIQRAKDGLSESE
                     YEEIYTKIQKKEIGLLEANYNNKQQKDKLAALEKSKQTIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLKVKSDFESKIEVIKDAIKGKEDNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELITKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSGSGSQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVVNQAKEQNRQIKEFLDQDAYQWQ
                     KTDNHILKVALAGSLDGKSRVGFENTYSIYDCNEEEVKKLLTGDEISFEVPLNQNFDA
                     IKYVTMYANIPNLRRNILDDSLKVKVHIHLYDSGYFSLYDDKKDTYYQYVFPQNYIDI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKKAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DLLTNEQKKKLESYFDKSSKYAWSESIDILKSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVNLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIID"
     gene            complement(9310..11826)
                     /locus_tag="ACOIAP_003253"
     CDS             complement(9310..11826)
                     /locus_tag="ACOIAP_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2640128.1"
                     /translation="MPEDNKTFLYELKELLSNGEKQIAKAIGQDLILILGGTGCGKST
                     AINYLAGCEMHKVEDEDTGVSYITCEDPVADIGSGAVSKTLYPEVIDMKKGFEGMTAK
                     FCDTAGFGDNRGAIHDICAAVSLGEVFKDSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKNSITFFISKSFLGRTEKQIYNVIKRKYEQLCEASDSNMSDSNSNIK
                     EKAWLFEEMLKDDGKNIHICNPLASDDREGLLRQVLELEEVKDKISAFQYPISADALL
                     VLDTLIKEIQDNIVSSLEDYVKAYTEDFISAVGSITMIEEIAKYDDVVEVFKNWLEST
                     TSPTIGRFINELARQSSLFLQDSCMKLQKNIKENLDIIDALSEYTEHGTSEILLSSVH
                     MEFIIEKTSKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNRENLMEVANKKDYKYS
                     VNDFNSILTNVTVTQKEELEDSITRLNAYGEEGNEIIREFISKYILNPFIVKTININD
                     KQGIEIRALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKNTIYMDDNLGMDFASEKNI
                     IIACNNLDVGSNVKINVSGKSGELVDNSMYGKNGEDGRDSGNIYLYIKEEIRNYRLTL
                     IANGGNGSKGIDGKNGETGASGSNGADAGYTSSFHGKMFKGYFAQGTSGGKGEKGGAG
                     GNAGRGGNAGKKGNIYFISDSEEQKNRIINRCDITVRDGEVGPNGRPGSGGYGGNGGY
                     HGYNTLSFSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPGREYAE
                     YGDRGADGGFNAPNTKISTAVSKIEDNFIKEKYQCYCSEI"
     gene            complement(12246..12533)
                     /locus_tag="ACOIAP_003254"
     CDS             complement(12246..12533)
                     /locus_tag="ACOIAP_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640129.1"
                     /translation="MRLNITKQNTIEVEGSKKEDVYFIIVDNVFFERKGNVFYSITNN
                     NLNNYDIKILPTDNIFLELKITSTKDLEPVFIVAEDRQYNHCSVMFKPVMV"
     gene            complement(12553..12828)
                     /locus_tag="ACOIAP_003255"
     CDS             complement(12553..12828)
                     /locus_tag="ACOIAP_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640130.1"
                     /translation="MSLIVGGWSKFRAVEEEDLKVFNEAVGMLKGVDYEPLIVATQIV
                     AGTNFKFICNATSVTNPPHDYLAEIIIFNPLPCDKQKATITSINIVK"
BASE COUNT         4097 a         2419 c         1285 g         5151 t
ORIGIN      
        1 ataaatttat attaaaatat atttacctat ataattttat ttatttttgg agtataatta
       61 taaaaaaaag aataggacat tttcctactc ttttctctgt acttatataa tattaaaact
      121 ctttattttt taatatatat tttaggtttt cttttttaat atatcttttt cttttaataa
      181 atatctttag ttttcttctt ctacatcaga gccaaaagga atccatgcat taccaaactc
      241 tttatcttta aataaataag ctaatccagt tatttgcttc aatctaagaa tttcatcaat
      301 ttccataccc aggtgctttg atatccattc atcagatttt ccaatttcac aaagttcagt
      361 tataatttta ctcattaaat ccacattatg agagcctctt gcacgattgt gtcgaatagt
      421 acttgccatt ctttcatcaa gagatttatc aattactgaa acaggaagaa gtccgttttc
      481 tctatcatat atatcctcat tttcaagcat tattctatag cgatgaaaac catctacaat
      541 aatatactta tctttttcct cattataata acagacaatt ggcattgtat acccatcttc
      601 ttttatactt ttgtacaaca actgcatttc tggtggggct actgcatttg gattatagtc
      661 gttagattct atcttttcga ttggcactgc gatgattcca tatacaggac ttttatattc
      721 catagcatct taactcctat ctaatgaatt ttttcatatt tcttcttaat atattctgtt
      781 ctaattctct gttcttttgt aggaccaaag cccataaacc tacacatatg gtcatttttt
      841 aaaatacaat aacacattct tttccagctt ggtatatcct tagtaaattt gatatcatct
      901 gtatcatcag gtatatcatc caaaaatata actctactct ttttatcttt tgtatgattt
      961 gaaactccat ttaattctat tttataacct tttctcaaca attcacggat aactatttct
     1021 gacaaaccac cacctgtatt ctgccaaaac tcaatagatg ttgaaaattt tttaatatag
     1081 ttatttctta tattttcagg taaggtatca agcaaaaaat atgtaaaact tttccacgta
     1141 tgtccatatg gtaacctaac actacgatat cccatagcct ttgtttttcc ataaatagag
     1201 gtaaaattaa ctccttgtac tctagcaacc aacttcaccc atacatctgg gtccaatatt
     1261 ctgtataaat ttaaactctc tttagctgaa tcattaaaag gtgatgccac tctcattttt
     1321 cttggagcta ttccagcttt atagaataag tcataaattt tattatagtc ataatcaaac
     1381 ttatagtggg ccaaccatat atcttctatt tcccaatcat atataggaga tgctgtccag
     1441 acatttttaa attccttagt tatccaacac tttcctttat atccatactg tttattcaca
     1501 atagaacaat aacgttgtag agattctgat gctcttgttc ctaataagca aacaactttt
     1561 gcaccttcat gtatatctct aatccatcta ccaaattgtt ttgccaaact ttcttgcctc
     1621 attttatatt tataataagt aaaaggatta tttttttgat ttattatgta ttctttgact
     1681 ggcatttctc ttacccataa ttcctctttc tcatcatccc atggatacca atacatttca
     1741 taacttccca cagcagttct tgtagccatt ggtaaacaca cccaatatgg ttcaatatct
     1801 tcaatgttct cttcaaatac tttttcaaca tattcagtag tcaaactgta ttgagcttca
     1861 aaatcttgat gaaatactcc tattttggaa cttatattat tctttctctt ataatccaaa
     1921 actaaattta gcagtaaacc actatctttt cctccactaa aagatacata gatataatca
     1981 aattcattga aaagataaga aagtctttct tgaaaagctt caaatacatc ggattctaaa
     2041 tatctcttat ccatttgaat tatccccttt caattagaag tttataaaat cttacaatgc
     2101 aatattatta tgctttttta gcagtaatca gcataaatta tacattttta aatacacaaa
     2161 tccaactaaa tacatataat tataatataa ttatactttt gtattataaa ctatatttta
     2221 tcattatttt acattttttt ccaacatata taaatatcat atttttatat tagctaaaac
     2281 taattacttt atatttttaa atattagtat aatcagacat aaaaacttga catactgttg
     2341 tcataattac tttgctatac ttaaaagtaa aaacggaggt aaattctaat gtatgagcgt
     2401 atgcttgata aaagcaataa accttgcttg tctcaaataa tagaatatat aggtaaaaat
     2461 ggatatgcac gcttgtgtaa gttggaaact tacttggaga ctcaatataa tttatcaaga
     2521 gaacttcgat ttccttttgg aaataattat ggttggggtt acaaatatag ccataaatct
     2581 tttcatttat tttatgcttt ttttgaaaaa ggtgcattca ctgttatgat tcaaataggt
     2641 gacaagcaag ttccagcagt agaaaaaatg ttaatatctt tgacaccaaa agctaaagaa
     2701 cactgggtca ctcgttatcc ttgtggtaat aatggaggtt ggattaggtg tcgtatttta
     2761 gaagatgcag acttacttga cattattcaa tatataagag caaaaaaagc tccacctaaa
     2821 caaaattaac ttttattttt tataatttaa atgtagtgta tataaattca attctttcta
     2881 tgtagaaaaa taataataaa aatatctgtt attatgcctt atttgatttt ttgcatatac
     2941 gtaaaaaatt ttatcataaa taaattgtaa ctaaatatcc tagtaaataa agttttattt
     3001 attctttttt attagaattt ttgataacag cccctataca tatgccaatt agcattccaa
     3061 aaactagtcc ataacacatt gtggtaccta cacttccttt ataaataccc ataacataac
     3121 ctatagccac tccaagtatc atgcctataa acatacatat aataaccaaa ttgtcgtttt
     3181 tattcatact tcttctccat tccatatatt ttaaattgct tagctcggtt tcttaactta
     3241 aaacaaagaa ctataaatta actttcttta attctaatat atactggtat aaatgtcata
     3301 taattttata aatttattaa taacaattat tacagagaca aattagtaaa taaactacta
     3361 atcaaaagta tatccaaaat atgtttccca aagtacttaa aatttttata atcgcactta
     3421 actctataaa atattttaaa aaaggtctct cttctctact aaataaaaaa ttagaaattt
     3481 ctattttaga tgcctctgct ataggtattt ctatttttag aaaggatata aatatggctg
     3541 gttcagtcat gtttcttatt ggtattgact aattattaga agaatgtatt agaaaaaaat
     3601 ctatatacaa tttgacacag tgaatttctt gaagtcaaca aaaaagaagg ctcttacata
     3661 tattctgaaa ctgtaataga ataatacaat attgttatgt gtctcaagga aaagcaaatg
     3721 ctactagatt tctccaaata gtaactatga ttgagaaatc cgaaaaatga gaatctcctg
     3781 acgagagtaa acttgaacat ctagcaaaca caatagtttc atacggcttt ttataaagca
     3841 tattagccta tacaattcct tgaaggtgta acatgtgcaa atactatttt attttataat
     3901 tcatccttta aaaagaagat gtcttaaaag tagttttttt ctaatcaaaa ttatataaaa
     3961 catattctac aaattttaaa ctcaacttct ttctattttt tacaaaaaag gagataattc
     4021 aaattttcat tttgaaaaat ctccttttgt aaattctttt aaaacttatc tattagttat
     4081 attttcaatc aataatcgta ttttcaacca atctttcttc atagcatttt aaatcatttt
     4141 gctttagata attaaattca gactctacat aaataccaca gcctaccaat tcaattgtca
     4201 aattaggtat attttccttt aatatactag tctgttcata aataattctt tccaataaat
     4261 taacttgtaa tatagaaaaa tgcttcataa tctctccatc actatctata tctttcttga
     4321 tttcatacca actctttgac aaaattccct tcaaatcaat ataccctaga ctcttcaata
     4381 tatctatact ctcgctccat gcatacttac tagatttatc aaagtatgat tctagtttct
     4441 tcttctgctc atttgtaagt aaatcataag aaagcttctt attaaaatgt gccttcaaag
     4501 aaatcttagc catagaatat ggacttctac cagagtttaa tcctgctttt ttgaactttt
     4561 caattccttt atcttccacc gaagaccata ttgagtttat tgaatctgaa tcattgtatt
     4621 taacatcaag accatgtgta atgtctatat agttttgtgg aaatacatat tgataatagg
     4681 tatctttttt atcatcatat aaagagaagt atccactatc atataaatga atatgcacct
     4741 ttacttttaa actatcatct aagatatttc gtctaagatt tgggatattt gcatacatag
     4801 ttacatattt tatagcatca aagttttgat ttagtggaac ctcaaaacta atttcatctc
     4861 ctgtcaaaag ctttttcact tcttcttcgt tacagtcata tatagaatat gtattttcaa
     4921 accccacacg tgacttccca tctaaacttc ctgctaatgc taccttcaaa atatggttat
     4981 ccgttttttg ccattgataa gcatcttggt caagaaactc tttaatctgt ctattttgct
     5041 ctttcgcctg atttacaacc tcgttttcat cttctgtaat ccctacatga catctattta
     5101 atatgtttac tatattgctt ccaaatggaa atgtccatag ttgaaaagct gctgcctcca
     5161 cctgacacaa atatctaacc tgatttaatt caatttgatg gataagtttt ttctgatatt
     5221 cattcatttg actaccacta cctgacattt gataaatcaa ttctcccatt gcaagattat
     5281 ctttcttctt atcaatctta tcagtaataa taatttgagt ttccatcata tcctgtactt
     5341 ttttaaatat tatagaaatc tcctctgaat tttccatttt taaacttcca aactttgtaa
     5401 ttaattcagt taaaacttcc ttcatcttta atttacttat ctcattttca aaaatatctt
     5461 gatttttaac tgtactatca aatttttcta caaatggtat aacagattcc ttcaaagttt
     5521 tatctttaaa ctccaccatt tgagtattca attcatctag tttcttaata ttatcttcct
     5581 tacccttaat tgcatcttta attacctcta ttttgctttc aaagtcagat tttactttaa
     5641 gacaattatt aacaccacta attgcagtat ttataagaga acaagcagaa cttccaatac
     5701 tcaatgcatt tttaatttta gatgtctttt gttgtctttc aatagtttgt ttacttttct
     5761 ctagtgcagc taacttgtct ttttgttgtt tattattgta atttgcttcc aacaaaccta
     5821 tttctttttt ctggattttt gtgtaaattt cctcatactc actttcactt aacccatctt
     5881 tcgctctttg aatatcgtca tctttgtctg aatagttatc atcatctata gacttaacta
     5941 taatctcctt aatttggtca aatttatctc tttttccttc atcaacacct gccaagttat
     6001 aagtcatttt atctaaagca ttttttctat cttcacttaa ctgttctcca agtacaaatc
     6061 tcataccatc agaatccaat ttaaaatctg aaaaatcaac catcctgtta gtccattggt
     6121 attcctcttc cttagctgaa agattttcct tcaaagattt tgcactgtca aatgctccta
     6181 aacaagcttg accaacgcca ctaaatgcag tcaataaact caatgcgctt tgtattccag
     6241 aaagaattaa ttgtgttttc atttgttcct caagttttgc ctgtttctct tttagtttct
     6301 ctatatcttc tttttcatct tcttttatct ttataatttc ttgaatcaac aagttcattt
     6361 ttgcattaac agaaagcatt ttattctcaa gttcattttt taaaacagct atttgttgat
     6421 ttccagattc aatttgagtt aggatacttt ccttatatgt attgaaatac ccttctttta
     6481 actcatcttt ctttccttct tccaactcct ttaagatctt atccagataa tctgtcaaag
     6541 aacgaatatc tgtaacacga tttcctccaa tttcactttc ttctatcatc tgcacataga
     6601 atgctgtttt ttgttcaagt gcaaataaaa tcatactcca ttcactaaaa ttctgctttt
     6661 ctcctatgaa agattctatt ctatcagact gcatcaattt atttataagg tattcatata
     6721 tttcctttgc ctctttataa aattctttct ttatattcat atcatccaga gaaagtactg
     6781 ctttattttt cttctcaaaa ccatagtatt tctgaaggat ttctctattt aactgcatct
     6841 ctattttctc aactgcatga aaaatttcat aaatatgtga aagttctaaa atatccgctt
     6901 ctaaaattcc tactgcacac aacagtctaa gatttctata acctttactt ccagaaaaac
     6961 caaatctctc gaaaaattca taaaagaatg tatctattga caaagaatgt tcttgcttta
     7021 acagttcctt ttcttttaat gtatctccag agagaccgtc ttttccctct gctccgactg
     7081 aacctgaatc ttcacgtttg ctaattgtcc agtccttatg tttttcataa agagcattta
     7141 atttcactcc atcatctgct acttccttct catctgaagc atgattaaac acatatctat
     7201 caaaataata gtagtttcta tcactatcat ctattggagc agagatgcct atatatctta
     7261 ttgtttcttc atagatacct ctaattccac caagacctcc tgcaccacca gcaccaccag
     7321 agcctccttt tcctgctaaa ccgtgattcc catctttctt acttatagca ccttttaata
     7381 aagtagcttt tccaaggaga taaacttgtc cagccttgct tccaagacct gcatttccac
     7441 cattacctcc tatacctcca gttccacctt gttttccttt ttctgctttt accaaatagt
     7501 attttgtatc tttatcctta gcaaattctt ttgactcttt tttagaacct attttagcgt
     7561 tttccccagc ttttccagtt agccctgttt ctcctatttt tccatcttgt ccatttccac
     7621 cacgtccacc atctacataa agtttaagtt ctcctatttt ttctatttct ttaaaagata
     7681 atataatatc acctgaagta cctgcattat taccatttct tccattcata ccattgtata
     7741 tataatcttc tccagccaac ttctccgcat tcttaccaga tacattgatt gaataagagc
     7801 cttctggtat aaatactttc tctgtaagca atacaatatt tttacctgaa aacacgtctt
     7861 tctccatact acaatcaatt tttaattcgc aatctccata catatatata gatgataaaa
     7921 tatcaagttt ataaccagat attattttaa tcaaatctga taaattcact ttaggtatag
     7981 gaatatatat agaaagtaca ttttctttct catatgattt tatatatgta caactttgaa
     8041 tcttctctat cctatattct gcatcttcaa gctttttggc ttcttcttcc ttatattctt
     8101 cctctgctat ccaatattta atatctttta acgtatcttc taaagtattt tttagtaatg
     8161 attttaacaa ctcacttaga ccaacaatat gggtctcact gcaatagcta tttaactcta
     8221 aaagaagacg tgtttcttct aatatattca ctttctgcat accatcacca tatgaaagtt
     8281 cttgtacaaa ctccataagc tctttcatac tattagctct accacataaa tccgtataca
     8341 tcctgtctaa ttgaattttt ttatccttta gactatttat agaagataga gtggaaatag
     8401 aatcttccat accttttttg acactttcta tataagggac taaaagtttt tctaactctt
     8461 tgtatgttac atcaacagct ttttgtatct ctattttaca agaagcagta agcatcaatc
     8521 ccagatttgt tttttcaaaa gtttcaggta aatttttcat tttatccaat aacttttctg
     8581 gatttttatc tagtgggtta cacaattcta tagatacact atctgataac attacatcca
     8641 ataagtaaat caattcctta catccatcat aatctatctc ttgtccatct aaatcttctt
     8701 ttgttttatt caatatattt cttatttttt cttctgttac attgcttatt agtgctttag
     8761 gtattttatt gataagaaag aagaaatttt ctttatactt tgcataatca ccaagcatat
     8821 ctttcaaatt tttgcccgtt tctattaata atgtatatct agagtctaat agggattgat
     8881 agtctaaaat aactaccatc cctttcacct ttgaagatgt agagatggtt tcccttacaa
     8941 gcatagcacc tgcaatcata tactctgctc cacggttatc aaaaaaacct gggcaatcac
     9001 ataatgaaaa atccctattt gcaatatcta caacttctgg gcataaagtc ttagaatata
     9061 caccatttcc aatttcgaca gccgaatctt ttgcagttat atatacttgc ccagtttctg
     9121 catctgtttt ttcttccatt acacaacctt ttaaataatt tatacaagta ctctttccga
     9181 cacctgaagc acctaaaaat aataaaatag acttcttttc taaattatat tttctaagct
     9241 cgtcccttcc atcttccaaa aggtttacaa ttccactata aagtttattt gccatatatc
     9301 tatccctttc tatatttcag aacaatagca ttgatatttt tctttaataa aattatcttc
     9361 tatttttgaa acagctgttg atatcttagt gtttggagca ttaaatcctc catctgctcc
     9421 tctgtctcca tattcagcgt attctcttcc tggtcctgtt ttaccttcat tccaacttcc
     9481 accactaaat tctatatgat atttaattat actatctaac ttataatccc aacttgtaaa
     9541 gtatcctgta tagtatacag tcttatctat accacttgga gaaaatgaaa gtgtattata
     9601 tccgtgataa ccaccatttc ctccatatcc acctgaacct ggtctaccat ttggacctac
     9661 ttctccatct ctcactgtta tatcacaacg attaattatt ctatttttct gttcttctga
     9721 atctgaaatg aagtaaatat tacctttctt accagcattt ccgcctcttc cagcatttcc
     9781 accagcgcca cctttttcac cttttccacc acttgtacct tgtgcaaaat accctttaaa
     9841 catctttccg tggaaactac ttgtatatcc agcatcagct ccattacttc ctgaagctcc
     9901 agtttcacca tttttcccat ctattccttt agaaccattt cctccatttg caatcagtgt
     9961 taaacgataa tttctaattt cttctttaat atataagtaa atattacctg aatctctacc
    10021 atcttcacca tttttcccat acatagaatt atctacaagt tctccactct ttccacttac
    10081 attaattttt acattactac ctacgtcgag attattacaa gcaataataa tatttttctc
    10141 tgatgcaaag tccattccaa ggttatcatc catataaata gtatttttag caaagaacat
    10201 aaatgtagaa acattgtcat ccacttttct atttttgaaa tattccaata cactactaat
    10261 tactaagttt ggaattaacg ctcttatttc aataccttgc ttatcattaa tattaattgt
    10321 ttttactata aatggattta aaatgtattt actaataaat tctctaatta tttcattacc
    10381 ttcttctcca tatgcattta atcttgttat actgtcttct aactcttctt tttgtgtaac
    10441 tgtaacattt gtcaaaattg aattaaaatc atttacacta tatttataat cctttttatt
    10501 tgcaacttcc attagatttt ctctatttgg taatgtaaat acctgttttt gcacttcata
    10561 agaaactaaa actttttcta aattctttct tattataatg aagttttgtt ccattatctt
    10621 cttacttgtc ttttctataa taaattccat atgtacagaa gataataaga tttcactagt
    10681 tccatgttct gtatattcac ttaaagcatc aattatatct aaattttctt ttatattctt
    10741 ttgtaatttc atgcaactat cttgtaagaa taaactgctt tgtctggcta attcgttgat
    10801 aaatctacct atagttggac ttgttgtact ttccaaccag tttttaaata cttctactac
    10861 atcatcatat tttgctattt cttcaatcat tgttatacta ccaacagcac tgataaaatc
    10921 ttctgtataa gccttaacat aatcttctaa gctagatacg atattgtctt gaatttcttt
    10981 tatcaacgta tctaaaacta atagtgcatc tgcactaatt ggatattgga atgctgatat
    11041 cttatcttta acttcctcta attctagtac ttgtcttaat aagccttccc tatcatctga
    11101 tgcaagcgga ttacaaatat gtatattttt gccatcatct tttagcattt cttcaaacaa
    11161 ccaagctttt tcttttatat tactatttga atctgacata ttactatctg aagcttcaca
    11221 taactgttca tattttcttt ttataacatt atatatttgt ttttctgttc ttcctaagaa
    11281 actctttgaa atgaaaaaag ttatactatt cttaaaattt tctttatgaa gacacatatt
    11341 taactgttgg aacaagtcta gtacctttgt aagtctagaa tctaatatat ctgcttctgg
    11401 tatcaagaca attactgcac atatagatgc agaatcttta aatacttcac ctaatgaaac
    11461 tgctgcacaa atatcatgga ttgctcctct gttatcacca aatcctgcag tatcgcaaaa
    11521 ttttgcagtc attccttcaa agcctttttt catatctata acctctggat ataaagtttt
    11581 agaaacagct cctgaaccaa tatctgctac agggtcttcg caggtaatgt aagatactcc
    11641 agtatcttca tcttctactt tatgcatttc acatcctgca agataattga ttgcagtact
    11701 ttttccacag cctgttccac caagaattaa aattaaatct tgacctattg ctttagctat
    11761 ttgtttttct ccgttactta ataactcttt taattcatat aaaaatgttt tattatcttc
    11821 tggcattcat ttgcctcctt gcttatatat tcttatttaa ataaagttta ataacttagg
    11881 taaattgtaa agtttttaga ctgtatttaa atttgttttt attttttgtt tttaatctgt
    11941 ttatattttc attttataat tatttatttc tattcattaa aataactgtg ttgtataata
    12001 taaaatttat caacacagtt attttagtta atgaacttat tttattgtac tttatgtact
    12061 acagttgttt ttatattatt tattcactat tttgctctat ttataaatat agactttctt
    12121 attaaaatta tatttctaca attaaattaa acattacatt gctattgggt tgaatatctt
    12181 aattttattt gattaaatat cacaccatta ctagcctgaa tattttaatt ttatttgatt
    12241 aaacactaca ccattactgg tttaaacatt acactgcaat gattgtattg tctatcttca
    12301 gctacaataa aaacaggttc taaatcttta gtagatgtta tttttaattc tagaaaaata
    12361 ttatcagttg gtaatatttt tatatcataa ttatttaaat tattatttgt gatactatag
    12421 aatacattac ctttgcgttc aaaaaaaaca ttatcaacta ttataaaata aacatcttct
    12481 tttttactac cttcaacctc tatcgtattt tgtttagtta tatttaatct catattccag
    12541 ctcctattaa tattacttaa ctatattaat acttgtaatt gttgcttttt gtttatcaca
    12601 aggaagaggg ttaaaaataa ttatttctgc taagtaatca tgcggaggat ttgtaactga
    12661 agtagcatta caaataaatt taaaatttgt tcctgctaca atttgagtag caacaataag
    12721 tggttcataa tcaacccctt ttaacattcc tacagcttca ttaaatactt ttaaatcttc
    12781 ttcttcgaca gccctaaatt ttgaccatcc accaacaata agactcatat aaaaaacctc
    12841 ctttatatat atatatttat ttatatagta gtactaattt tcttaatatt caatattttt
    12901 gtataactgg tcaataaata cgtataactg gataaaaata cttataaaat aa
//
LOCUS       DBGJFK010000095        12855 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.097, whole genome shotgun sequence.
ACCESSION   DBGJFK010000095 DBGJFK010000000
VERSION     DBGJFK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12855
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.097"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(465..995)
                     /locus_tag="ACOIAP_003256"
     CDS             complement(465..995)
                     /locus_tag="ACOIAP_003256"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HGZ2640131.1"
                     /translation="MLTLGLHFGEAVSLRWCDVELDEGIINIKQTMIYVREKVTFKSP
                     KTEKSKRILTTPIELINLLKEEKIRQNKLKLQDILKNELDLICLNKYFRPWKQQMFFR
                     LFNRLLEKNNLRYIKLHELRHTNATLMLLSGTNIKTISERLCHADIKITMNRYSLVLE
                     DIDREASDNLSKILFK"
     gene            1838..1990
                     /locus_tag="ACOIAP_003257"
     CDS             1838..1990
                     /locus_tag="ACOIAP_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640132.1"
                     /translation="MDNFLQGILASLVASLIVYLTSKLFKKVKSHSGRSDFSFELEIK
                     FKKNKH"
     repeat_region   2269..5199
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2269..2297
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaag"
     gene            5580..5711
                     /locus_tag="ACOIAP_003258"
     CDS             5580..5711
                     /locus_tag="ACOIAP_003258"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640133.1"
                     /translation="MDESNKLILELNNIFCELESINKYKFNEYKEIVKNLHNKKEEE"
     gene            complement(5914..6102)
                     /locus_tag="ACOIAP_003259"
     CDS             complement(5914..6102)
                     /locus_tag="ACOIAP_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2640134.1"
                     /translation="MTLQDRIKEERLKLGLNQVELSKKFNMTKQTVSNWESENRIQDT
                     LMLTKLADFLCISRFSLG"
     gene            6290..6523
                     /locus_tag="ACOIAP_003260"
     CDS             6290..6523
                     /locus_tag="ACOIAP_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640135.1"
                     /translation="MNTKKTKGIYKNGGLKVSRTAICSVCGELLVDGYGDEFTNTKII
                     DLHGREFVIIIYKNCLEELLRKCANGGISNDNN"
     gene            6510..6767
                     /locus_tag="ACOIAP_003261"
     CDS             6510..6767
                     /locus_tag="ACOIAP_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640136.1"
                     /translation="MIIIRSQDRLDLMRVNRVEIDSKYVYAVFGEESNVREIGRYKSE
                     ERAIEVLSRIQDAIIAGTKFDIIKKDGVRYYKEKVFEMPVE"
     gene            6781..7140
                     /locus_tag="ACOIAP_003262"
     CDS             6781..7140
                     /locus_tag="ACOIAP_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640137.1"
                     /translation="MLKVEKYFSGSLGINIIEDDPTCRNYLALYCCLVGIERKGKKVI
                     PRIDSMLSEFGVKSRCKRPHNNKLIRLINVKTGEVKEFKSIDSTACFLGLKQPAVSHI
                     LKRKTPSRSGWRAEYIK"
     gene            7146..7280
                     /locus_tag="ACOIAP_003263"
     CDS             7146..7280
                     /locus_tag="ACOIAP_003263"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640138.1"
                     /translation="MEVSRTEYTIKRAKELYGNGKDMFIAIDNSREEYEEIVKNEYFN
                     "
     gene            7677..7871
                     /locus_tag="ACOIAP_003264"
     CDS             7677..7871
                     /locus_tag="ACOIAP_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640139.1"
                     /translation="MNILIYKYIVNEHRDEADELDRDYGEFKIFNGGKCFSGCGRNFY
                     TLAKFKKMIITCPHYEKNIK"
     gene            8857..9429
                     /locus_tag="ACOIAP_003265"
     CDS             8857..9429
                     /locus_tag="ACOIAP_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HGZ2640140.1"
                     /translation="MNENLSKEIKILGTIEVEEMKFHDIEGGFGVGKKSMSVKDIDEI
                     HNGKLKDINKNINNNRKRFKDMINTLDLKVSDLKSLSLEMGYSNQSYANANNIYLLPE
                     RDYSKRLKILEGKQYEKIVDGYFSMRKELNNPLLSASKELQAIFMLDKKQEFLETKIE
                     SVNEKLENFMDDAPLFNIEFESIVKIVLWK"
     gene            9872..10243
                     /locus_tag="ACOIAP_003266"
     CDS             9872..10243
                     /locus_tag="ACOIAP_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640141.1"
                     /translation="MKKQIMALGLTGLIGLGGLGLLANKSFADTPNKLKGDTTVAQGL
                     NKNATAKDVTEQVDTTIGKGLDKNAIVKDVVENNGEKSDTTVAPGLDKNATVKDTAEK
                     GNTTIAPGLDKNTIVKDIVVK"
     gene            10421..10639
                     /locus_tag="ACOIAP_003267"
     CDS             10421..10639
                     /locus_tag="ACOIAP_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640142.1"
                     /translation="MKKNILGVLLPLLTMIIIFVLSFENIITNSLGLSDMDIKGILIS
                     GVVLYIPVSFLVNGIICAKKQIKWKISK"
     gene            11004..11246
                     /locus_tag="ACOIAP_003268"
     CDS             11004..11246
                     /locus_tag="ACOIAP_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640143.1"
                     /translation="MEAEMYVQVAMMASKVVKITGVDEVIKKLVKKFLNNKVEEALGK
                     QRSKKELKLIENNFNEYMERSYKNYIYMNTIVFRNQ"
     gene            complement(11523..11759)
                     /locus_tag="ACOIAP_003269"
     CDS             complement(11523..11759)
                     /locus_tag="ACOIAP_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640144.1"
                     /translation="MAPNFNVENIVLEDKEIVSTPQKYVLISRYYDNGKTIAFIEMNS
                     TKYKTEYIRNFDQYVDEFSTLEETEECLQECLSA"
     gene            12102..12323
                     /locus_tag="ACOIAP_003270"
     CDS             12102..12323
                     /locus_tag="ACOIAP_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2640145.1"
                     /translation="MVSISFGEKIKIILKRKNMTIGELAEKTGQTRQNLSNKFSRDNF
                     SEKEIRKFAKILECEFDFYFIIKDTNEKV"
     gene            12343..12648
                     /locus_tag="ACOIAP_003271"
     CDS             12343..12648
                     /locus_tag="ACOIAP_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640146.1"
                     /translation="MEVTLHTGEINFFKEHEVAKNYIGELYNFIEEYKLSMETVSILT
                     NIDIKKLNDFYIGKGTLHYDELVLINSVIIMPFIDVFKTAKHNYEMIIKSSKKYEED"
BASE COUNT         4943 a         1266 c         2025 g         4621 t
ORIGIN      
        1 aataaagaac agtatttaat aaaattaaaa aaacaaatta gataactagt ttataagttt
       61 attttcttgt tattttaaat tgctactatt aaatttgtct aatttaactt cttcaataat
      121 agtccaatta tacatactct ttatgcatct tcagatgcat ctaagaaacc tgaataatgt
      181 tctcatattt tatttttaaa aagaatatat tctttagtaa ttttttatat taattgagga
      241 tgtaaaaatt tattgataat ttttacatat tgatgtttat taaaaaaatt gctaaaagca
      301 gtaatattaa taggtatgtt atgtttagct attatataat actactagat agcagttaaa
      361 tactagtttt tgctactatc tagtaataaa tatttgattg atatttaact gacaattaaa
      421 aaaatatgtg attaactgac atcttactga catagaactt agcattattt aaatagtatt
      481 ttacttaaat tatcagatgc ttctctgtct atatcttcta aaacaagaga gtatctattc
      541 atagttattt ttatatctgc atgacataat ctttctgaaa tagtttttat attagttcca
      601 gaaagcaaca ttaaagttgc atttgtatgt ctaagctcat gtaattttat atatctaaga
      661 ttgttttttt ctaataatct gttaaaaagt ctaaagaaca tttgttgttt ccaaggacga
      721 aaatatttat ttaagcatat taaatctaat tcatttttta gtatatcttg taattttagt
      781 ttattttgtc ttattttttc ttcttttaat aaatttatta attcaattgg tgttgttaat
      841 attcttttag atttctctgt tttaggtgac ttaaaagtta ctttttcacg aacataaatc
      901 attgtttgtt ttatatttat aattccttca tcaagttcaa catcacacca cctaagcgat
      961 acagcttctc caaaatgtaa tccaagcgtt aacattaaat aaatagggat agctaagtta
     1021 gtttcaagac atttttctaa tagaaactgt gctttttctt tagtataaaa gttagttaca
     1081 gatgtatttt tttgcttgaa gttattacaa acttagaaac atcttcttgt atttctctaa
     1141 gtatgtaagc ttcatgtaat aaaggattta agaaaccaat cgaatttttt gcagaattta
     1201 aagaatattt tttataaatt ttattaacat atatttttag aagatttgga gtaatatcaa
     1261 ttaactttac atcttcaaaa aaggtttgat ttttaattat accttgtcta tttctcaaag
     1321 tatacagaga aatattatct ttttttcctc tatgtatcta tagcaccttt ctacaagtgt
     1381 tacatcactt ggagcaacaa acttattgtt gtctatagtt gattttattt caattaaatg
     1441 tttttcagca tcctttttct tttaataact tccataactt ttttgtttct ttttgtcggt
     1501 ttcttcttcc acatattcca catatacatg aaatttccca cctttttttc ttataaaagc
     1561 tgatttgata ttcatatgta cacttcattt ataagtattc ttgatacatt aaataaatag
     1621 ggttttatta tatcaaatct aagttataaa tactatttga tgatagggta gttgtatata
     1681 aatatataga tgaatttttg aaaaagtaat gtagtaggga aaatatgtaa aaatatatgt
     1741 tataatcttt tcagcaagaa gatgtaatct acaatttata gagtggagtt catacaaaag
     1801 ataatcctcc caacgtatag aagggaggtg aatatgtatg gataattttt tacaaggtat
     1861 attagcaagt ttagttgcca gtttaatagt ttacttaact agtaagttat ttaaaaaagt
     1921 aaaaagccac tctggcagga gtgactttag ttttgaacta gaaatcaagt tcaaaaagaa
     1981 taaacattag tatttgaact tcactctacg tctaaataga ttgtagttct tcttgttttt
     2041 attataccac aaattggtgc agatattcaa aaataatatt tttatgatat aataaagata
     2101 tagaaatttt gcagtgttcg attttttgaa taaaataggg cttaagcatt gaaatataag
     2161 gcgttgaaga tgtatgataa gtgttatcat ttgcaccact gctcgctcac tgcaaatttt
     2221 agagtgttgc atatgtgtaa gtgttggaaa tgctaagttt attttggggt tttatattaa
     2281 ctatgtggta tgtaaagtag actgatattc atccatactg atgattccta aagaagtttt
     2341 atattaacta tgtggtatgt aaagagggtt gagttctggc gtattaagag gtgaggagcg
     2401 ttttatatta actatgtggt atgtaaagtg gagaaggtct tggattagca ccaataggtc
     2461 atagagtttt atattaacta tgtggtatgt aaagagtgaa agcaaggcta ttcctaattc
     2521 ttggagtgga gttttatatt aactatgtgg tatgtaaaga aataagtttt gaagcagaat
     2581 ttacacacaa taaactagtt ttatattaac tatgtggtat gtaaagaaat aaaagaatta
     2641 ggatttactc aacaatcaat taagttttat attaactatg tggtatgtaa agaccaattt
     2701 ttgtatgcta tatcacaatc tttactctcg ttttatatta actatgtggt atgtaaagtc
     2761 ttccacttta ggtttatatg ctgacctata ctttggtttt atattaacta tgtggtatgt
     2821 aaagctgcat tatctacaag tgggtggttt tttaaattag tgttttatat taactatgtg
     2881 gtatgtaaag aagaaagaca aacatgttca aagtcatgtt caaacagttt tatattaact
     2941 atgtggtatg taaagcggca aataagagca gtatattcat cagatttaaa tagttttata
     3001 ttaactatgt ggtatgtaaa ggaggttgat gcttatagat taagtaaatt agctactggt
     3061 tttatattaa ctatgtggta tgtaaaggtt agtgtatgtc ctggtactaa cgctaccttc
     3121 attagtttta tattaactat gtggtatgta aagtcattat aaccccaacc aactacagtt
     3181 gcagggattt gttttatatt aactatgtgg tatgtaaagt atagctaaat ctattgtgga
     3241 tttaattatt tctgcctcgt tttatattaa ctatgtggta tgtaaagaac tcttttgcta
     3301 ttcgtttcac tacattatta tcatgtttta tattaactat gtggtatgta aagaaaagta
     3361 atgagagttt agaagataga aggtttagga gttttatatt aactatgtgg tatgtaaagt
     3421 tattttctct gataattcta ctaaggtatt atttaaagtt ttatattaac tatgtggtat
     3481 gtaaagatat gacagcacaa ggaacaccta cagcacaagc agttttatat taactatgtg
     3541 gtatgtaaag aaaaactaaa acagtctatg gctatatgaa aatctcgttt tatattaact
     3601 atgtggtatg taaagaagaa aataagacgt tcaaatcaaa aaagacgaag tagttttata
     3661 ttaactatgt ggtatgtaaa gtctattcca acataaagat acaaagtagt ttctttttgt
     3721 tttatattaa ctatgtggta tgtaaagaaa caaatcatca cacaagcaat tattatgctt
     3781 actaagtttt atattaacta tgtggtatgt aaaggtcgta aaacttaaag atgaaacaaa
     3841 aggaatgatt gttttatatt aactatgtgg tatgtaaaga gattcgacgg agaactttta
     3901 tctaataaag aaaaacgttt tatattaact atgtggtatg taaagatcac ctggtgatat
     3961 acccctctat catctcctgc tagttttata ttaactatgt ggtatgtaaa gtggtttgtt
     4021 gcaacatatg tgttccttca acatatccgt tttatattaa ctatgtggta tgtaaaggaa
     4081 tctggagcag gtttataagt ttctggatag ctagagtttt atattaacta tgtggtatgt
     4141 aaagaaaaaa tataaaagag ctaagcacat gaaggataat gttttatatt aactatgtgg
     4201 tatgtaaagt atgttaaatt tgttgatgaa ttatatccca atttttagtt ttatattaac
     4261 tatgtggtat gtaaagcacc tctcactact atagaatctt tatcaacgct aagttttata
     4321 ttaactatgt ggtatgtaaa gggaagtata atttttactt tatctccata ctcaaaaagt
     4381 tttatattaa ctatgtggta tgtaaagtgt attgaggggt cgaaaataag tgtgttcaaa
     4441 cttagtttta tattaactat gtggtatgta aagtttgtaa atgtaacagt tttatctaac
     4501 attttaccgc gttttatatt aactatgtgg tatgtaaagg tatttagata ttgcaagtaa
     4561 attaccttcg gtatcgtttt atattaacta tgtggtatgt aaagtttcat ctaatacctc
     4621 cttgttttat caagagggtt aagttttata ttaactatgt ggtatgtaaa gattaattca
     4681 gaacttgcac agttgtatat agaacttgtt ttatattaac tatgtggtat gtaaagatat
     4741 tcatatacta catattcttt tccttcatca ttaagtttta tattaactat gtggtatgta
     4801 aagaggtcta aaatttgtat ttagacatac taagttattt gttttatatt aactatgtgg
     4861 tatgtaaagt cacaaaaaca aggaatactt aagttagcat caatgagttt tatattaact
     4921 atgtggtatg taaagtagag tattgttcta caattatatt tccaactgaa ctgttttata
     4981 ttaactatgt ggtatgtaaa gtgaagtttt cttttaaatt atcatcctgt atagccttgt
     5041 tttatattaa ctatgtggta tgtaaagata caggaacagg agtcggaaca gaaaaaaacg
     5101 cctcatttta tattaactat gtggtatgta aaggttgtat tacctctgta attatttttt
     5161 ccaaaattac gctttatatt aactaagtgg tgaatttaag aagttacaat gagtacaaga
     5221 atgtttctat ttattgtaac tttttttatt acaaacttaa atttatagta tattataaaa
     5281 atcattataa aaagatgatt taataaaaaa atataattaa aaaaacgatt aataatctat
     5341 aaaaatggaa aaaacatcca atatcctaca aaaatagatt tttttattac aattacaagt
     5401 ttttattgca tctatttagc aaaagtatta ttatgcaagt aagataatta tcaaagacaa
     5461 ttctgaatag tctgatttaa aagatacaat taaaggatat aaataggaat aatttataaa
     5521 tattacagaa gatttataac taaaattacg aacgtaagtt tgttatatgg ggtagttgtg
     5581 tggatgaatc aaataaatta atattagaat tgaataatat tttctgtgaa ttagagagta
     5641 ttaataaata taagtttaat gaatataaag aaattgttaa aaacttacac aacaaaaaag
     5701 aagaggaata atttctcttc ttttaaataa aattattttt gattatcaat ctttgatttt
     5761 tcttcctcta taaagacatg agcaattttt aacatcttat ctttagtttt atcatctaaa
     5821 tcaagaaata tctttattaa ttcttttaca tcgtcataac tatctagttc atcaatgaaa
     5881 ttttcataat tatttatttg ctcattatta gctttacccc aaagagaatc tactgataca
     5941 caaaaagtca gctaatttgg taagcattaa agtatcttga attctatttt cgctctccca
     6001 attacttaca gtttgcttag tcatgttaaa ttttttagac aattcaactt gatttaagcc
     6061 aagtttaagc ctttcttctt ttattctatc ttgaagagtc ataatattgc tccttttatt
     6121 gatgtttata taagtaacta taaactattt gttatatttt ttataaaaca tataataaaa
     6181 taaatacttt ttcgaaaaaa atgtaaaatt tgtgttgata gtaaactaaa agtagactga
     6241 tatataaata taaagttaac ataaagttga ctagaaaaga ggtgttaagg tgaatactaa
     6301 aaagactaaa ggcatatata aaaatggagg tttaaaagtg agtagaacag ctatatgtag
     6361 tgtttgtggg gaacttctag ttgacggtta tggtgatgaa tttacaaata caaagatcat
     6421 agatttacat ggtagagaat ttgtaattat tatatataag aattgtttag aagaattatt
     6481 aagaaaatgt gctaatgggg ggattagtaa tgataataat tagaagtcaa gatagattag
     6541 atttaatgag agttaataga gttgaaatag atagtaaata tgtatatgca gtgtttggag
     6601 aggaatcaaa tgttagagaa ataggtaggt ataaatcaga agaaagagct attgaggtat
     6661 taagtaggat acaggatgct atcattgcag gaactaagtt tgacattata aaaaaagatg
     6721 gggttagata ttacaaagaa aaagtgtttg aaatgccagt tgaataagga ggggtctgaa
     6781 atgttaaagg ttgaaaaata ttttagtggt tctttaggaa taaatattat agaggatgac
     6841 cctacatgta ggaactattt agcattatat tgttgtttag ttggaattga aagaaaaggt
     6901 aaaaaagtaa taccgagaat tgatagcatg ttatctgaat ttggtgtgaa aagtaggtgt
     6961 aaaagacctc ataataataa gctaataagg ttaataaatg ttaaaactgg agaagtaaaa
     7021 gagtttaaat ctattgatag tactgcttgt tttttaggat taaaacaacc agcagttagt
     7081 cacatattaa aaagaaaaac tccaagcaga agtggctgga gggctgaata tattaagtag
     7141 gaataatgga agtttcaagg actgaataca caattaagag agcaaaagag ttgtatggca
     7201 atggcaagga tatgtttatt gctatagata attctagaga agaatatgag gagattgtta
     7261 aaaatgaata ttttaactag tattacatta ataatgacta gttttataat aggtagaatt
     7321 tatgaatata gattgaattt aaaagagtgt gaaaattgta atagtaaagg ctacgagaat
     7381 atatgaaatt tatgtagata aatagtaaag gcaattttat gaatgaaact aaaaacttta
     7441 tagaattact ttaatttata taaaggagta attattaata tgattacaac agaatttata
     7501 gttacttggt agacaactag aaaacgggaa aaaggaaaga catatagtca tgtatttaca
     7561 gatttagaga aagcaagagc atttaagaaa gaggaggaaa atataaaaaa attataatgt
     7621 gaagctttta agtagagcta tagtcgaaat cgaaatagat taggcaggtg tttttaatga
     7681 atattttgat atataaatat atagttaatg aacatagaga tgaagcagac gagttagata
     7741 gagactatgg agaatttaaa atatttaatg gaggtaaatg ttttagtgga tgtggtagga
     7801 atttctatac attagctaag tttaaaaaaa tgataattac ttgcccacat tatgagaaaa
     7861 atatcaaata aaacttttta aaaatggaaa agtgaatatg agagtaattg agtaaataaa
     7921 ggaaagtgat tatatgaaaa gaagaagatg cagttggtgt gggaaattat tttatcttaa
     7981 ggaaaaatct aaggaggttt attgttataa ggaatgtaaa aagaaggcta acagggtaaa
     8041 gagctttaat gactaaggaa tataatttaa aacaaaataa ttagaaggta aaaaatattt
     8101 aattaattat actttttacc ttcttaaaat agaaaaactt aactattaag atatttgtga
     8161 gggttatgta tccaaaataa taatattatt gcaaatagag gactgaacca aaatgccagt
     8221 aaagtataaa gactactatt taaagcattt ttagtcgaaa ctctattaca agcgattaat
     8281 agtattatag ataaaatatt agcaataatt tctaatatat ttgaattaaa gtcttgaaaa
     8341 aagactaaaa aagaaaaaat ataagagata ctcatacata taaaaaaaca ataattcagt
     8401 attttaaatt ttaatagttg ttttttatta tcattgattg ccataagtac tcctaaaatt
     8461 atagatagta tgataaatgt atttgatgct tgcaaataag aaaagatagt cataaattta
     8521 ttctcctaat attaactata aattgtaaaa aaataattta aataactaac aattgaataa
     8581 ccaataaaaa atgtaaataa ataaaaaaga aactttttaa atccatttaa tttaaatctt
     8641 ttttctatct tttgacaaat gaaatttatc ggaataaaaa caaaagtcgc aattaaaaaa
     8701 gttattaaat actttgacat aggataatag tccataaata atcacctcat aaattagtat
     8761 aaccatagat taatatgagt tgttaataat agcaatcaat ttttcagaac tgtaaataaa
     8821 ttgaaataaa ttatccaaaa aaaagagcaa tagactatga atgaaaattt aagtaaagaa
     8881 attaaaatac taggaactat agaagttgaa gaaatgaaat tccatgacat tgaaggtgga
     8941 tttggagtag gtaagaaatc gatgtcagta aaagatatag atgagataca taatggaaaa
     9001 ctgaaggata taaataaaaa tataaataat aatagaaaaa gatttaaaga tatgataaat
     9061 acattagatt taaaagtgag tgatttaaaa tcactgagtt tagaaatggg ttactctaat
     9121 caatcttatg caaatgcaaa taatatttac ttattacctg agagagatta ttcaaaacga
     9181 ctaaagatat tagaaggtaa acaatacgag aaaatagttg atgggtattt ctctatgaga
     9241 aaagaattaa ataatcctct tttaagtgca tcaaaggagt tacaggctat atttatgtta
     9301 gataagaaac aagaattctt agaaactaaa atagaaagtg ttaatgagaa attagagaat
     9361 tttatggatg atgcaccact attcaatatt gagttcgaga gtattgtaaa aatagtattg
     9421 tggaaatgaa aatttcccta tcaaaactaa ataattggct agggttaagg gattacccta
     9481 gtcactatga acagactagg cagggcgtga ggacgctatt agttcaattc taactatgtt
     9541 caaaatcatt gatacactat attaagtatc tgaattgaga ctaaaattca tacagttttg
     9601 tatcttaatt cagaatctga aaattgagtg gggtttggca acctcactaa ccatgcagat
     9661 actggtattt aatctaagtt cgattcttag gacctgctac ataatatgaa tctccctctt
     9721 tataaaatga ctaagttcgg gtaagcttag tcttttattt tttaaacaag aaaatgagaa
     9781 tttggattaa ttagcattgt aaacaatcag taaacattaa tatgatatta tttgtttaga
     9841 aaataaaaca aagaaaaagg agagaataat tatgaaaaaa caaattatgg ctttaggatt
     9901 aacaggatta attggcttag gaggtcttgg attacttgca aataaatcat ttgcagatac
     9961 tcctaataaa cttaaaggag atacaacagt agctcaagga ttaaataaaa atgcaactgc
    10021 taaagatgtt acagaacaag tagatacaac aataggtaaa gggttagata aaaatgcaat
    10081 tgttaaagat gttgtagaaa ataatggaga aaaaagtgat acaacagtag ctccaggttt
    10141 ggataaaaac gcaactgtta aagatactgc agaaaaaggc aatacaacaa tagctccagg
    10201 attagataaa aacacaattg ttaaagatat tgtagtaaaa taatttagtt tttatagctg
    10261 gcaaaagggt ggaaatttat tctgcccttt tgttttatta ataaaaattt acatatatta
    10321 aatatggata gcaaagactt agattaattt ctagctcttt tatattttaa aggttgtgtt
    10381 tatggtaaaa tgtactaaac taattggtgg ggtgataact atgaagaaaa atattttagg
    10441 agtattgcta ccattactaa caatgattat aatatttgtt ctatcatttg aaaatataat
    10501 aactaatagt ttaggattaa gtgatatgga tataaaagga atccttattt caggtgtagt
    10561 attgtatata ccagtttcat ttttagttaa tggtataata tgtgctaaaa agcaaataaa
    10621 gtggaaaatt agcaaataaa gtggaaattt ccagttttaa tatcattttt aggctcagtt
    10681 gttattatga tgtatctaag ttttgatagc attgaaatgg cattgtattt atcatattat
    10741 tttatatcat attatattgg atattggata actagtgcaa tgaagaaata aaattaaggt
    10801 gtaaatataa aaaatagaat aagttgagag actatcttta taaatggtct ttttttatac
    10861 aatgaatcaa aaatgaaata tatttatgca ttatggagag aaatatggta aaagtattat
    10921 ttggaattat tttgtagtta tagaatagtt tttgaaggat attgaccttt gaagttgaat
    10981 tttatacttt tgaggggatt aatatggaag cagaaatgta tgtgcaggta gctatgatgg
    11041 caagcaaagt tgtaaaaata actggtgtgg acgaagtgat aaaaaaatta gttaaaaaat
    11101 ttttaaataa taaagtagaa gaagcgcttg gaaaacaaag gagtaaaaaa gaattaaaat
    11161 taatagaaaa taactttaat gaatatatgg aaagaagtta taaaaattat atatacatga
    11221 atactatagt atttagaaat caataaaaac aattgatgat ttatatatac cattaacagt
    11281 ttcaaagcgt aatatttttg atgcttcttg tgaagaagat gtaactgata ttttaatcaa
    11341 tagttataaa agatgacttt ttaccaaagt acaaaaagtt tttgttgata gaccaagcag
    11401 gtatgggaaa atccgactat agctaaatga ttatctaagt caaaacttct atttatctct
    11461 agttgtttgt tatttacaag tcttttcagt atataagtct taaaacacat ttatatcacc
    11521 ccttaagcac taagacattc ttgcaagcat tcctctgttt cctctaatgt agaaaattca
    11581 tcaacatatt ggtcgaagtt tctaatatat tcagtcttat atttagtgct attcatttct
    11641 ataaaagcaa tagttttacc attatcataa tatctgctta ttaagacata tttttgtggg
    11701 gtagatacaa tttccttatc ttctaggact atgttttcaa cattgaaatt aggtgccatg
    11761 ctatagttac ctactcttat gtattcataa tcatcactga aacggatttt atcacgtcta
    11821 acagagtcat cttctttata agttataagt tttatcagtt cttttaataa cttctatcgt
    11881 gtatatgcag tcaaggtcac atatacttct tgttgcataa gttttaccta cttcaaattt
    11941 tatcatttta aatacatcca ataattaatt tgttaagttt attgtacact ataaagtgtt
    12001 gtttataaat ataaaaatga aattaaataa ttttttttgt aaattaaata cagataaaaa
    12061 aaactatata gtgtataatt atatagaaaa gcgaggtggc tatggtgtca atttcatttg
    12121 gagaaaagat aaaaataata ttaaaaagaa aaaatatgac tataggtgag ctagcagaaa
    12181 aaacagggca aacaagacaa aatctttcaa ataaattttc aagagataat ttttcagaaa
    12241 aagaaattag aaaatttgca aaaatacttg agtgtgaatt tgatttttat tttattatta
    12301 aagatacaaa tgaaaaagta taaaatagga ggaaattttt atatggaagt aactttgcat
    12361 acaggagaga ttaatttttt taaagaacat gaggttgcaa agaattatat aggagaatta
    12421 tacaatttta tagaggaata taagttatca atggaaacag tatctatttt gactaatata
    12481 gatataaaga agttaaatga cttttatata ggaaagggaa ctctacacta tgatgaatta
    12541 gtacttataa acagcgttat tataatgcct tttatagatg tatttaaaac tgctaaacat
    12601 aactatgaaa tgataattaa aagcagtaaa aaatatgaag aagattaata gaaaaaaggt
    12661 agattctata taagtagtag ctacctttta ttgttgttga taaagctggt gataagttat
    12721 ggaaaactca tataaaaatt gtggataaaa tattttactg acaaaagtta aaaaaataaa
    12781 tgctgtaaat attataaaat gttgaaaaat agccatatat atataatata agtaacacta
    12841 taggtaaatt actgt
//
LOCUS       DBGJFK010000096        12851 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.098, whole genome shotgun sequence.
ACCESSION   DBGJFK010000096 DBGJFK010000000
VERSION     DBGJFK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12851
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.098"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            186..896
                     /gene="rgaR"
                     /locus_tag="ACOIAP_003272"
     CDS             186..896
                     /gene="rgaR"
                     /locus_tag="ACOIAP_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HGZ2640147.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            1942..2955
                     /locus_tag="ACOIAP_003273"
     CDS             1942..2955
                     /locus_tag="ACOIAP_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGZ2640148.1"
                     /translation="MNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYIFISDKF
                     DDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNIRLINLS
                     LSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGLTLDVDDS
                     FWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEKPGITIS
                     DLNDKLESLAIRNHWNSCDFDECSRIVNFKLDLYDKENDLLIKVADVVRDCLNIEDNN
                     EKLFKCSLFNKEIGLVYDNCFNLLKKLEYRFDVKFNYMDISKYDLVSIYTLTELVERY
                     KNL"
     gene            3088..4386
                     /locus_tag="ACOIAP_003274"
     CDS             3088..4386
                     /locus_tag="ACOIAP_003274"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGZ2640149.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVREGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVNFDDVNIKKSDINSQIYDCTVMKENYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLIKTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKD
                     RKLTLLIGMLEDKDIDSVLEVLLPHFNKVITTTPINPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(4506..4751)
                     /locus_tag="ACOIAP_003275"
     CDS             complement(4506..4751)
                     /locus_tag="ACOIAP_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HGZ2640150.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            4899..5765
                     /locus_tag="ACOIAP_003276"
     CDS             4899..5765
                     /locus_tag="ACOIAP_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HGZ2640151.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(5769..6305)
                     /locus_tag="ACOIAP_003277"
     CDS             complement(5769..6305)
                     /locus_tag="ACOIAP_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HGZ2640152.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(6496..6699)
                     /locus_tag="ACOIAP_003278"
     CDS             complement(6496..6699)
                     /locus_tag="ACOIAP_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HGZ2640153.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            6990..7754
                     /locus_tag="ACOIAP_003279"
     CDS             6990..7754
                     /locus_tag="ACOIAP_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2640154.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESRPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            8144..9457
                     /gene="prdC"
                     /locus_tag="ACOIAP_003280"
     CDS             8144..9457
                     /gene="prdC"
                     /locus_tag="ACOIAP_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HGZ2640155.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQDDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      9860..9945
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            10240..10368
                     /locus_tag="ACOIAP_003281"
     CDS             10240..10368
                     /locus_tag="ACOIAP_003281"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640156.1"
                     /translation="MDNQQVSFEKKKLQRLERNLVPTSVGKWGVPNLWLGNDIVCA"
     gene            10512..12590
                     /locus_tag="ACOIAP_003282"
     CDS             10512..12590
                     /locus_tag="ACOIAP_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HGZ2640157.1"
                     /translation="MKTKIKKSSIISVVIAFSMVFTAFTPIVSYADEVIGNDTIINGE
                     KPLEGQTPEGEKPLEGQIPEGEKPLEGQIPEGEKPLEGQTPEGEKPLEGQTPEGEKPL
                     EGQTPKGEKPLEGQTPEGEKPLEGQTPEGEKSLEEEIVIEEMSLKQDIDKILDMTLSQ
                     INKIVYNFWEDEENVKSDEQSEINQVFTSKDSFISLWYDKKAKVKNTCLLKEIDGSDR
                     PYHDLRFDDITKTLTFDYVIKGLVGASSKDNKYVIEGEDGEQTAFCYNNHLRPPSSNG
                     KSPYLPAEEFSGQENQNEDAVKSILYAGSEFDGFGYKQQFNLGGEENDIMTYSATQSA
                     IWIILGQVDEQEKLKQYQGSINFCDFLIENAKNEEEKAEYQKKKEVAINTKAYLEALL
                     KAGREELKPNDTGKPSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLRLPDGVTA
                     YDGDGNIIGTGEVEISTQQKFKLKSVGKPDAKANISAISYDYIFPKAIQYYKAVIDLG
                     QKDHSSSLPSSKQNLLSYTVEKKNGQEVNFNISLPTDDVVNPPVPPTDDTVINPPVPP
                     TDNTNGHKPKPSPPIDDTVINPPVPPTDDTVINPPVPPTDDVVLNPPVPPTDDAVLNP
                     PVPPTDDAVLNPPAPPVSDTVEKMPELSKYDTIVKSPKTGDETQLMSYVFISIIAICG
                     LAYQFKIKRN"
BASE COUNT         5202 a         1364 c         2157 g         4128 t
ORIGIN      
        1 ataatatctc tagaaaagta taggaattta tcgtaattta agtttaaata ttaaagagaa
       61 tttctatagg tagtttaatc gacaatttaa atttataaag aaatttaaat ttgaaagcta
      121 gtaagtacag tttggaaatt gaaataaagt aaactaaatg atattttaga tttggaggtg
      181 atattatgtt cagggtagtt atatgtgatg acgaaaaaat acaaagaagc atactaaaag
      241 agtttacaga aaaacttttg tctgaaagat gtctaaatta tcaaatactg gaattttcct
      301 gtggggaaga tttaatatcc aaatacccag aaaaaattga tattatattt ttagatatcc
      361 aaatgaaaga tatcaatgga attgaggtgg ctaaaaaaat aagaaagttt gatgaaaaag
      421 tagaaattat atttacaaca gctttttcag agtatgctcc ccagggttat gaggttcgtg
      481 cttatagata tttagtaaag cctatagagt atagtaactt tgcaatgggt gtaaatcttt
      541 gtattgataa ccttcaaaga aagaaggagc gttatatagt tttaaatagt aaaaaaggat
      601 ttaatagaat actgatagat tctattttat atgttgaaac tgtaaagaga gatttagttg
      661 tacatacaat aggtagagat tataaagcta atatgagcat gaaacaagca gagaaattac
      721 tgtgtgaaaa tggctttttt agatgtcata caagttttat tgttaattta agaagaatag
      781 aagatcttag ggataatatg attactatta atgaacaatt tatacctata agtaagtata
      841 gacttaaaga tttaaaagta gcattaacaa gcttgttatg tgatataatg tattaatttt
      901 aaaaaggtaa gtgaaaatat cgtaaaaaat atttaatgtc atcacagggc tattgattaa
      961 aactgtctta atatataaaa gattatttat attaagacag ttttattatg taaaatagta
     1021 gtttatagac ttttaatatt gtttaatatg tatatgtaga aattacatta tagtagcttg
     1081 attattaata tgctatgatt gatttttatt tatagtatat gcctttttcg aatatgctta
     1141 cttttttaaa tttatgacta tttataaagc tatatagata tttgtttcat tttactatgt
     1201 atactttaat taattatatt aatatttaag gaagtacaat ataaatatta aagtgatatc
     1261 ttatagttta ttaaacttat agtagtggac taataaatag tttaattcta tgaaaagatt
     1321 tccttttatg caatttattt attgaaatat gatataatat atgaaggtat aagtattagt
     1381 tgttaagata atatttatat tagtttttat gtatacttag tgcaagtttt tcatatattg
     1441 attaaaattg atggtgattt attattttta gtattttttc gccttttgat tcatactttg
     1501 tagaatggtg tattttgtaa aactgattat aagacaagtt tattcaaatt agcattttta
     1561 tagcatataa atgattgttc cccctaaata agacttagat atatagtatt aaaatcaaaa
     1621 agtataaaat aaaattgatg cttaatcata gataaatatt aataaaatat acaaggggat
     1681 tgtctaataa aaaagataat ctcctttttt acaaataatt ctaaattgtg atataaatct
     1741 aaaaatttta tcttaacatt taaccattta atgataataa ttgatataat aaatataaat
     1801 taaatatata gtgtacttat tttatgtttt tagcaagaaa tatagcattt aaaagataaa
     1861 ttgtgcaact taaatcaaag tttaagatga actattaaca tagatatatt aaaaactttt
     1921 gtaatggaga atatatgtga tatgaataat aaagttaagg ttgcagtatt agatacagga
     1981 atagacaaag aacatgatta cttaaaagat aatttagttg gaggaattgc ttttgaatgt
     2041 atgcatgatt atatctttat atcagataaa tttgatgatg aagatggtca tggaactgct
     2101 tgtgcatcaa taataaagaa agagtatgaa gatgtagagt tatttgtaat aaaaattttg
     2161 agaaaagatg gtattacaaa tataaaagtt cttgaagaag cattaagata ccttttagac
     2221 actaacataa gattaattaa tttaagttta tcagtcatag gagtagaaag tgttaagggt
     2281 ttgtttgaag tttgctatga attgtttaga aaaggaaaga taatagtatg ttcactcgct
     2341 aatgattttg acttaagtta tccagctatg tttaacaatg ttataggtgt aaggggactt
     2401 actttagatg tagatgattc attttggtac aataaaaaat atgatgttca atgtgttatg
     2461 gatagcaatt catatataag ttgtgacata aataattcct atagattgcc accaaaatgt
     2521 aatagttatt tgtcagcaaa gcttactggt aaaatagcta agatattatc agaaaaacca
     2581 ggcataacaa tatctgattt aaatgataag cttgaatcat tagcaattag aaatcattgg
     2641 aatagttgtg attttgatga gtgtagtaga attgtaaact ttaaattgga tttgtatgac
     2701 aaagaaaatg atcttcttat aaaagttgct gacgttgtta gagattgttt aaatattgaa
     2761 gataataatg aaaaactatt taagtgtagc ctttttaata aggagatagg tttggtttat
     2821 gataattgtt ttaatttatt gaaaaagcta gagtatagat ttgatgtaaa gtttaattat
     2881 atggatatct caaaatatga cttagtttca atatatacac tgactgaatt agtggaaaga
     2941 tataaaaact tataaataaa gatttgtagc taaatttaat gtagaaggta ttaaattata
     3001 tatatccttt gtcagtagat taaaagcaaa aaatatacta taattagata gcataagaga
     3061 aaatgccaat acagggggaa ttagataatg aaatatgaag aagcattaga gtatatatca
     3121 caaactaata aattcggtat aagattaggt ctagaaaata taggaaagtt attagaatta
     3181 ttaggaaatc cacaagaaac tttgaatata atacatgtag ctggaactaa tggaaaaggt
     3241 tctgtgtgtt cttttgtttc taatatacta agagagtgtg gatataaagt cggtttatat
     3301 acatctccat atttagaaac ttttactgag cgtataaggg taaatggaca gaatatacca
     3361 caggatgatg ttgctagaat aattgaatta ataaaagaaa aaatagagat tatggtaaga
     3421 gaaggctatg catatccaac agagtttgaa gtggttactg caatggcatt ttattactat
     3481 tcagagcaaa aggtagactt tgtggcatta gaagttggtt taggtggcag atatgatgcc
     3541 acaaatataa taacaaaatc acttgtaagt gtaatcgtat ctataagttt ggaccataca
     3601 gggatacttg gagatacaat agaaaaaata gcgtatgaaa aggctggaat aataaaggaa
     3661 aatggagtag tactagtata tgaccagact gatgaagcaa aggatgttat aaagtcagtt
     3721 tgtaaggaga aaaaagctaa atatatagaa gttaattttg atgatgtaaa cataaaaaag
     3781 tcagatataa attctcaaat atacgattgt actgtaatga aagaaaatta tagagacctt
     3841 gaaataaaat taatagggga acatcaaata aacaattcta tattggcaat tagtgtaata
     3901 aaatatctaa aagacataaa taaattagca aatataaatg aagaatctat aagaaaagga
     3961 cttataaaga ctaaatggcc aggaagaata gaaaagataa aagaaaatcc aatttttata
     4021 atagatggtg cacataatga agatggagca aaatctttgg caaaagcact tgataagaat
     4081 tttaaagata gaaaattaac cttattaata ggtatgttag aagataaaga tattgacagt
     4141 gttttagagg tattgttacc acattttaat aaggtaataa caacaacacc aatcaatcca
     4201 agggccataa attcagatat attaagggaa aaagtattaa aatatgtaga tgatgtaaca
     4261 tcaaagcatg agatagagga tgcagtaaat tatacattag aaacgtcaag tgaagatgat
     4321 attataataa gtgcaggttc attatatatg attggtacag tgagaacttt agtaaagaaa
     4381 ttataatttt ataaaataaa tatacaaata taaataaaag tataaaagag agttgtctaa
     4441 aaaatggaca actcttttta tataaagtaa gtttttaata attttattga tatttataga
     4501 agcaattata tagattgacg tatagcttta gataattggt ctgggcaaga agtacctttt
     4561 ccaccacaat caataccgtt taatttatca gcaacttcaa gagcattttg accaattatt
     4621 aagcttctaa gtcctgataa attaccatta catcccccta taaattcagc atcaacaatc
     4681 acattatttt catcaacttc aaaaatcatt tctctacaac agacaccact tggattaaat
     4741 gttactttca ttaaaaagac ctccattaaa ttttatttct ttttttaaca ttaataataa
     4801 taccaaatat atgagtaata atgcaactat aaagcataat acaagctaat gaaataatat
     4861 attattgtag tatatgtatt gtagagagga ggggttatat gaaaatctat atttctaact
     4921 atttatcaaa gagcattagc atagttgatt attctacact tgaactagaa aaagaaatag
     4981 tattagaaga taatatatat ccacaccatt tttgcataga aaaagaaaaa aatttaatat
     5041 acatacctag ttcaagtaat gggatactct atgtcttaga tttaagcaat gataaaataa
     5101 ttgatactgt ttctataggt ggaagtctta gtcaagttgt acttagcgat aatgaattat
     5161 ttgtagcaaa tgaagattct aatagtatat atgtactaga taaaaacaca ttaaatccaa
     5221 taggaattat tggagttgat aatatgccac atggatttga ctttgataga gaaagtaaaa
     5281 agttatatgt accgtgtata aactcgatag tatgtataga tacaattaat aaaaatatac
     5341 aaaagaaaat aaatatggac tttagagctt ggcatataga acttgataaa caaaagaaag
     5401 aaatgtatat atcaacactt gatggaaagc ttataataat agatgaagta agcatggata
     5461 taaaaaaggt attatatgaa tttttattac cagtagaaat aagatttaat tatagtggca
     5521 aaaaagttta tgttgctgat ttgggatata ataatgtaag aattttagat tatacaacga
     5581 gtagatacat tggaaatatt gaaataaatg ggattcctca gggcttagaa atatctaaag
     5641 atgaaaagtt actatttgta tcagatacac aagaaaattc agtaaaagtt tatgaaactg
     5701 caaataacaa attaataaaa gaaatcaagg taggaaaaga gcctacaact ataatttgtt
     5761 tgtaggcttt aatgtatgtc tcttataagt aagtcgataa cttcggcata catataagat
     5821 gcattatttt tccagttatt gcaaataagt tttgcttgtt tctctgatga aacatttaga
     5881 tttaaatcta ttaagttaga ctgattttct atgactctaa ggttaacaat aaattcatta
     5941 tcactttgtt ttacaaaact agactttact tgagtatctg ctagtaaatt ttctttgtta
     6001 gaatctatat acttgtctat tttttcagta acactagtag gtattcgatt aaagaagtat
     6061 tccagacttt ctacgcctct ttgagtaaga gcataatatt ctctgtcaga gtctttatat
     6121 gtagtcaaaa acttagattc cataagctga gataaaagct gttgtaatga aaaataattc
     6181 atcatttcag tctctaatac tacttgagtt atttgagaat tagttaaatc cattttaatt
     6241 ttttctaata tatataaaat taaaagtttg tgataggcta attcttcaga cgagttttca
     6301 aacataaata tcatcctccg tcaaactatt tctatatata atatattaaa ctaatttgta
     6361 caaaattaaa agaacaattt gtattgtatt attaatcttt aataattcat ataaaaacaa
     6421 ttttataaat aaatatagag aaacagggct actaattagc agccctgttg atacccaggt
     6481 gtcaaaattt actatttatt ttccagccat ttgtctttca gccatttcaa ctaatttctt
     6541 agtcatatat ccaccaacat atccattttc tctagctgtt aagttacctt tgtctatgtt
     6601 ttcatagtta gataaaccta tttcattagc tatttctaat ttcatttggt ttaaagcagc
     6661 ttttgcttct ggaactactg ttctgtttga atttgacata gtaaatttcc tcctcaaata
     6721 attagtttat gatgtctaac aacactttta tttatgtgat gttaatacta atttctccaa
     6781 aataaaaata atatatacag aaaaataaag gtaaaaatgt aaaaaatata aaaaaattaa
     6841 acaaacgagt attttagaga gtttaattag gtcaatatag gttttatttt tttagttatt
     6901 gtcttataaa ttaaatatta cagtactttt ttgagctgaa aaaaaataaa ttttaaatat
     6961 agaagaaatt atttaaaagg gggaatagta tgaaaagaga agttaaaagg actaaagctt
     7021 tgatatatag tgttttattt ttttcattat tattagtgtt aatatttgtt tttgtttatg
     7081 gaataaaata catatgttct aaatctgaca attcaaaaat gcctatatat aaagttgata
     7141 caaatgagaa aaaaatagct ttgagttttg atgtagcatg gggaactgat aatatggatg
     7201 atattttaaa aattttagat aaacataatg taaaagctac ctttttttta gttggtagtt
     7261 gggtagatga taatgaagaa attgtaaaag ctatagatga aaagggacat gaaattggaa
     7321 atcattcaaa tactcatgcc aatttgaagg aaatatcaaa agaagacata acaaaagaga
     7381 tagaaactac atcagaaaaa atatataata taacaggaaa aaagactaat ttatttagac
     7441 ctccttttgg ggatgtaaac aacaaagcta tggacatttg tagtgattta ggttataaag
     7501 taattaagtg ggatgtagat tcgatagatt ggaaggagct tggaccaaat cacgtaattg
     7561 aaaaagtaat aaaagaatct cgaccgggtt caatagtttt atttcatgcg aatataaatg
     7621 atgtagataa ctatttggat actataataa gtcgactaaa aaaagatgga tacagtctag
     7681 tcaaaatatc cgatttgttg tataaagata attatgtagt tgattccaat ggagtgcaaa
     7741 aaactaagaa ttaataagta ataaatgtat attttaagca aagttgtggt aaattatata
     7801 gtatatgtta gaaaagtgtc gataaaaaga cggtgtctat tttttgacac tttttataca
     7861 tgtatgcaat atcaataatt atagattaaa ttgattgaaa aaagtgtcta ataattgact
     7921 tttttttgac gggcttaaaa atttagaaga attaataaat gctgtaagat agtatttcca
     7981 aagggtataa gtttatttga aagttggcat agaaattgct ttgttaataa gcgatatgtt
     8041 ctatagaaat aaacgatatg ttaagacctt ataatagaaa aatagcatta acattatttg
     8101 aacagcttat aaaaaaatta atatacttaa gggggcgtac tagttgaaca aactatattc
     8161 tattttatta aaacaacacg ttggtggtcc agataagcca gtagtaagtg ttggagatgt
     8221 agtaaaaaaa ggaactctaa tcgcagaacc aactggatta ggggcaaata tttatgccag
     8281 tgttagtgga aaaataagtg aaataaatga ccaagcgata gtaattgaag ctgatgaagt
     8341 acaagatgat acttttgaac cattaaaagg agaaggtata cttgacttaa ttaaagaagc
     8401 tggagtagta ggaatgggtg gagcaggatt ccctactcat gtaaaattaa acatagattt
     8461 aaatggtgga acaatattag caaatgcagc tgaatgtgaa cctttattag ctcataatat
     8521 aaaagaaata gaagaaagac cagaaatagt ttatcaaggt ataaaatatg ctatggaagt
     8581 tactaatgct ggaaaaggta tgctagcaat aaaaagcaaa catccaaaag caatagaagc
     8641 tttcaaaaaa gtaataaagc caggagacaa catagaagtt gcagaactag ttgatatgta
     8701 cccaatggga gaagagagag caatagtaag agacgtttta ggaaaattac ttgagccaac
     8761 tcaattacct tcagaggcta atgcagtagt aataaacgta gaaacattaa ctagaatagt
     8821 agaggctgtt gagcaaaaaa gaccagttat atctaaaaat ataactgtag ttggtcaatt
     8881 aaatagtgga aaagagtcta tagtatttga agatgtgcca attggaacaa ctgttggaga
     8941 attaattgaa agagctggtg gaataaaagg tgaatatggt gaaataatct taggaggacc
     9001 tttcactggt aaagctacta ctttagatgc tccaataact aaaactagtg gtggtataat
     9061 agttactatg ccatttgtta atgaaaagag aaaaatgggt cttttagtct gtgcatgtgg
     9121 acctaatgaa gagagaatga gagatatagc aactaaaatg ggagttactg atatagtatc
     9181 agttcaaaaa tgtaaacaag ctcaagaaat taaaggtgca ttaaaatgcg aaaatccagg
     9241 acactgtcca ggacaagctc aaaaatgtat agaatttaag aaagctggag cagaagttat
     9301 attaatagga aactgtactg actgtagtaa cacagtaatg ggttctgcac caaaattaaa
     9361 attaggtgta tatcatatta ctgaccatgt aatgagaaca gttaatcacc cattaataag
     9421 aagaataaaa ggtgatgtaa gattaaaaat aaaataatag ataaatagaa gctaaacatc
     9481 cttagaagta aaacttaaaa gttacttcta aggatgtttt ttaatgtact ttgagggtaa
     9541 gatatatttt aaaataaatg gaaaaaatag acaaaatata ctagatattg tataatgata
     9601 acaatagcta ttacaattaa tattggacaa aaataatgat actcaaatat gtgatttgta
     9661 ttgatatgta tattatatta agtcaactat ccaatagagt aaaaggtttt tgtgacattt
     9721 gaagatactc tatagtatct tttttagtgt aaaaactaag ttttgtcttt tattagataa
     9781 gtatcttgga tactagttta tattttatta agttgttaaa aaagtgcact taaaaagtta
     9841 aaaaagaaaa attaaaaaac ctatttatag aaactgtgaa gtatatctta aacttgggca
     9901 cttaaaagat atatggagtt agtagtgcaa cctgctataa atataaatag gagtaacttt
     9961 taattgtcaa aaatatataa aatacataaa taagtaatta gtagaagata gatataaata
    10021 tatttttgaa atgctcccta cattcataac gagtgtagag tggcagatac ctgcccaaaa
    10081 ctcctttaat tgctggaagt tcctaaagct aactaaacca caacataatc atgaaataag
    10141 gataagtgtg atagagtgtg tatttaataa gcacttaagg ttacgaaagt agaaaaaatt
    10201 agttagatag cataaggtta aatcctaagt gccttgaaaa tggataatca gcaggtaagc
    10261 ttcgaaaaga agaaacttca acgactagag agaaatctcg tacctacaag tgtggggaaa
    10321 tggggagtac ctaatttatg gttaggtaat gatatagtct gtgcttaata gaaatattaa
    10381 gaagttcata ggagaactgg ttaggagtaa cgcccctaat tgaacacact aaagatatat
    10441 tgttgaataa gattcatata atatttaatt attaaatgaa tacaatatat gtttttagta
    10501 tcaggagaat tttgaaaaca aaaattaaaa aatcaagtat aatcagtgtg gtgattgctt
    10561 ttagtatggt atttactgca tttacaccaa tagtatctta tgctgatgaa gtaataggca
    10621 atgatacaat aattaatgga gagaaaccat tagaaggtca gactccagaa ggagaaaaac
    10681 cattagaagg tcagattcca gaaggagaaa aaccattaga aggtcagatt ccagaaggag
    10741 aaaaaccgtt agaaggtcag actccagaag gagaaaaacc attagaaggt cagactccag
    10801 aaggagaaaa accattagag ggtcagactc caaaaggaga aaaaccatta gaaggtcaga
    10861 ctccagaagg agaaaaacca ttagagggtc agactccaga gggagaaaaa tcattagaag
    10921 aagaaatagt tatagaagaa atgagtctaa agcaagatat tgataaaatt cttgatatga
    10981 ctttatctca aataaataaa atagtatata acttttggga agatgaagaa aatgtaaagt
    11041 cagatgaaca atcagaaatt aaccaagtct ttacttcaaa agactcattt atcagcttat
    11101 ggtatgataa aaaagcaaaa gtaaaaaata cttgtttact aaaagaaata gatggttcag
    11161 acagacctta tcatgattta agatttgatg atattacaaa gactttaact tttgactatg
    11221 taataaaagg tcttgtagga gcaagctcaa aagataacaa atacgtaata gaaggtgaag
    11281 atggagagca aactgcattt tgctacaata accatttaag accaccaagt agtaatggaa
    11341 agagtccata tttaccagca gaagaattta gtggtcaaga aaaccagaat gaagatgcag
    11401 ttaaatctat actatatgca ggttctgaat ttgatggatt tggatataag caacaattta
    11461 atttaggcgg agaagaaaat gacataatga cttactcagc cactcaaagt gcaatttgga
    11521 ttattcttgg acaagtagat gaacaagaaa aacttaagca gtatcaaggc tctataaact
    11581 tttgtgattt tcttatagaa aatgcaaaaa atgaagaaga aaaagctgag tatcaaaaga
    11641 agaaagaagt tgcgataaat acaaaagctt atttagaagc attgttaaaa gcaggtcgtg
    11701 aagagttaaa gccgaatgat acaggaaaac ctagtttaag taatggttta actaagatta
    11761 actttgaaaa aaatgaagat ggtacttatg aaacagaagc tgtagcctta gtaggttata
    11821 gtggtgtagt aaagttaaga ctaccagatg gagtaactgc ttatgatgga gatggtaata
    11881 taataggtac aggtgaagta gaaatttcaa cacaacagaa atttaaactt aagagtgttg
    11941 gaaaaccaga tgccaaagct aatatttctg ctatatctta tgattatatt tttccaaaag
    12001 ctattcaata ttataaggca gtaatcgatt taggacaaaa agaccactca tcttcattgc
    12061 catctagtaa gcaaaattta ttaagttata cagtagagaa aaagaatggc caagaagtta
    12121 actttaacat aagtctacca acagatgatg ttgtaaatcc accagtgcca ccaactgatg
    12181 atacagtaat aaatccaccg gtgccaccaa cagataatac aaatggacat aagcctaaac
    12241 cttcaccacc aatagatgat acagtaataa atccaccagt accaccaact gatgatacag
    12301 taataaatcc accagtgcca ccaacggatg atgtagtgct aaatccacca gtaccaccaa
    12361 cagatgatgc agtgctaaat ccaccagtgc caccaacaga tgatgcagtg ttaaatccac
    12421 cagcaccacc agtaagtgat acagtggaaa aaatgccaga actatcaaaa tatgacacaa
    12481 tagtaaaatc accaaaaaca ggtgatgaaa ctcagctaat gtcatatgta tttattagta
    12541 tcattgccat ttgtggatta gcttatcaat ttaaaataaa aagaaattaa tctagattat
    12601 tattaagttt aaaataaaaa gtctcaaatt gatttataag tcattttggg acttttttat
    12661 gtaaatataa tatgtaaata tagcttgttt aaaagtatct attttaatta tattcttaaa
    12721 cttatgatta gatataggta ttcattagtt gtttgatgaa tagaaaaatg ttttgaaggt
    12781 gaaaatagta ttgaaaaaat aatatactaa gggtataatt catttgattt catttgtata
    12841 aatttaatta t
//
LOCUS       DBGJFK010000097        12484 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.101, whole genome shotgun sequence.
ACCESSION   DBGJFK010000097 DBGJFK010000000
VERSION     DBGJFK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12484
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.101"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            119..745
                     /locus_tag="ACOIAP_003283"
     CDS             119..745
                     /locus_tag="ACOIAP_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2640158.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMNNKLYSTVESNIIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNTIFASENTNDTPSNNGIKMLDKCLSTGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLTENFLDILVGGLYNENSQQI"
     gene            723..1127
                     /locus_tag="ACOIAP_003284"
     CDS             723..1127
                     /locus_tag="ACOIAP_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HGZ2640159.1"
                     /translation="MKIHNKSSNKKKKYLKISITIFFVFICIIILIVSNLKPENLVVK
                     DINIANIKNGIYTGSADNKLVKATVSVEVNNGKIQNINILKHDNLLGKPAEKITTNII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            1130..1603
                     /locus_tag="ACOIAP_003285"
     CDS             1130..1603
                     /locus_tag="ACOIAP_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HGZ2640160.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNITIVDINNNNKIELSK
                     FDKIIIGSSIYAGSVSKKIRLLCNDNLELLNKKQVGIFLCCGFSEEADKYLKSNFPSS
                     LLESANAIGIFGGEARLEEMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLISLNN"
     gene            2153..2818
                     /locus_tag="ACOIAP_003286"
     CDS             2153..2818
                     /locus_tag="ACOIAP_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HGZ2640161.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGMATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKANIIMAVIALVVATIQFTLYDKKLNNS
                     HKK"
     gene            2840..3772
                     /locus_tag="ACOIAP_003287"
     CDS             2840..3772
                     /locus_tag="ACOIAP_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HGZ2640162.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVIFAKYEEPNENFGKEHADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFANSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            3793..4434
                     /gene="pcp"
                     /locus_tag="ACOIAP_003288"
     CDS             3793..4434
                     /gene="pcp"
                     /locus_tag="ACOIAP_003288"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGZ2640163.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQKHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTVI
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIK
                     GGFIHIPYMTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(4554..4886)
                     /locus_tag="ACOIAP_003289"
     CDS             complement(4554..4886)
                     /locus_tag="ACOIAP_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGZ2640164.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            5152..5772
                     /locus_tag="ACOIAP_003290"
     CDS             5152..5772
                     /locus_tag="ACOIAP_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGZ2640165.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKEAI
                     PGCISCASCFETGKCILNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(6085..6909)
                     /locus_tag="ACOIAP_003291"
     CDS             complement(6085..6909)
                     /locus_tag="ACOIAP_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraX family protein"
                     /protein_id="HGZ2640166.1"
                     /translation="MDFLKKGISGFTIKVLALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMVVEGFCYTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGVIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIVLGIFTVTLLFKATNKII
                     ILFMILVPVPFLVEGGPVWIILGIIFYLCRGKKFSLSICYVLMCIFIFTAMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(6920..8323)
                     /locus_tag="ACOIAP_003292"
     CDS             complement(6920..8323)
                     /locus_tag="ACOIAP_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2640167.1"
                     /translation="MKWKITRNFIFTIVFVVISVVIINIISILYVISTDNFLKVVDSR
                     NNPEEFARSFEKDLYEKDGELKLSKIGADKLEKSNSWIQVLNDLGEEVFGVNVPKDTP
                     QKYTPFQMVNNYKYIETEYVNFVLEKYLNKKHLNIIVGIPSRDVSRIILTYSQNNTKK
                     TLNKIIIIILVIDGMVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FSEDEIREYAEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKVNLVGLVRNIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVKIVKKD
                     NIEIIIKDSGVGISKNDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYL
                     NSEIGIGTEIIIEINQN"
     gene            complement(8327..9052)
                     /locus_tag="ACOIAP_003293"
     CDS             complement(8327..9052)
                     /locus_tag="ACOIAP_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640168.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLSNIYTAKTRKEGLEVFK
                     NINPDLIILDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDSQNENTDSDNNEEKTISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFANNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLSVKED"
     gene            complement(9164..9934)
                     /locus_tag="ACOIAP_003294"
     CDS             complement(9164..9934)
                     /locus_tag="ACOIAP_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640169.1"
                     /translation="MYLVKIEMIKILKSKSVWIIWLFLLFFGFVLIRKFDVLDTYADI
                     FYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKSGKKSVVLSKLVANGLILS
                     IINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSSLNLTVIQMYIIVILTTIFASF
                     VFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQI
                     VRYNVPSILIGFSIVISIILMIVLTKITYKNFTSSKRF"
     gene            complement(9943..10830)
                     /locus_tag="ACOIAP_003295"
     CDS             complement(9943..10830)
                     /locus_tag="ACOIAP_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640170.1"
                     /translation="MNKLEIKNLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQIFYNGEDIFKMDDDYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLKGKYLSSKIEELLDLVGLYDVRDKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKISRNKIIVLSTHIISDIESVAKETIMIKDGKLLMKGTHKE
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSIVLRIVSEDIPIGDNIQPVQ
                     AKFEDVYMFYFDLEDAREA"
     gene            complement(10843..11865)
                     /locus_tag="ACOIAP_003296"
     CDS             complement(10843..11865)
                     /locus_tag="ACOIAP_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640171.1"
                     /translation="MVNWEIKKLIKSKSMFISLGILILILSINIFVKPVLETENYYID
                     KERGRIEDTRNSEEIGNYKFQNKINVLKQLSSQKDMDVFSKKIKSISTNKLYNLIINE
                     YKDVSFWKVFNYRATNSLINVGMLIIIVIIISNIYVDELVFSVRDIILSSKEKKKALN
                     SKIVIAFLVPLTIYSVYLIGIFITTCMQQGMPINGDLEAFRIVDNIATLKCNSSIINY
                     VISNIGIEFLMFEGLAMIALLGSFISKSSITSISFFIFTIVITKIISVIHILPKNLLL
                     AISTVNYYDLIFGFNKIIGNYLGEIIIFKIHIDIVNLLIGVLVAIFIGAMSFCFIIIK
                     SDYISK"
BASE COUNT         4551 a         1769 c         1470 g         4694 t
ORIGIN      
        1 tattagccat aaaaatatat taacttatat tatttaataa tttattgaca gtattaaact
       61 taaattatac aataacagtg taaattaaat taacactgtt aagtgaagag gtgattaaat
      121 gagtattaaa gaaagacgta aaaatgaaaa agaagaaatg aagaaaaaga ttatggatgc
      181 tagcatcgaa attataaatc aacatggata tgaaaattta tcaataagaa aaattgctac
      241 aaaaatagaa tattctccaa ctacaattta tctttactac aaagacaaag cagagattat
      301 cagcgatatg aacaataaac tttatagcac agtagaaagt aatattattg acattatgaa
      361 taattgttcg tcgctaccaa tagataaaca aatcatagaa attatgacta gctttataaa
      421 aactctttct agtgaaccag agatggcaaa agctatcatg catagtagaa tgaatactat
      481 atttgcatct gaaaatacaa atgatacgcc tagcaataat ggtataaaaa tgcttgataa
      541 atgcctttcc actgggattg aacagggaat atttaaaaaa aatatagata aaagctcatg
      601 gatgcttata agtgcattgt taggattcgt tttatgtgtt gttgaaaata aattatattc
      661 tttacataat ttttctcaac ttacagaaaa tttcttagat attttagtgg gaggacttta
      721 caatgaaaat tcacaacaaa tctagtaata aaaagaaaaa atatctcaaa atatctatta
      781 ctatattctt tgtatttata tgtattatta ttttaattgt aagcaactta aaaccagaaa
      841 atttagtagt taaagatata aatattgcta atattaaaaa tggcatttat actggaagtg
      901 ctgataataa actagtaaaa gctactgtgt ctgttgaagt taataatggt aaaatccaaa
      961 atattaacat cctaaaacac gacaatcttt taggtaaacc tgctgaaaag attacaacaa
     1021 atattattaa acaacagtct ttagatgtgg atgctataac ttctgcaact tatagcagta
     1081 atactatacg aaaagctgta gaaaatgctt taagaaaagg agaataatta tgaatactat
     1141 tattatatat tcaagtaaat atggttgtac aaaagactgt gcaaatatac taaaaaataa
     1201 actctcagat aatatcacta ttgttgatat taataataat aacaaaattg aattatcaaa
     1261 atttgataaa attattattg gaagctctat atatgctggt tcagtttcaa aaaaaatacg
     1321 attactatgt aatgataatt tagagttatt aaacaaaaaa caagttggta ttttcctttg
     1381 ctgtggcttt tctgaagaag cagataaata cttaaaatca aattttccat catccttgtt
     1441 agaaagtgca aatgcgattg gaatttttgg tggtgaagct cgattggaag aaatgaaatt
     1501 tttagataaa cttattatga aagctgtttc aaaaggtaat tatgacagtt ttagaatatc
     1561 acaggataat atagataatt ttttaataag tcttaataac taaaataaaa ctaattatct
     1621 ctatgataaa ctcttttatt tctaagtaat attgctcaaa atagtcttta gactttatta
     1681 aaattttatt tttcttaatg aaatctaata aaactagtac tcaatatatg ttttgttaat
     1741 cataataaaa aggtagtatc tgatgaactt tttagttcat tggacactac ctttttgcat
     1801 ggaatcaaat atatttttat catttcaaca ttaaaaaata gacttctctc tattttgaga
     1861 tattctcttt ttataatata atatttaatt taaaactact attttaaata ttaccacata
     1921 cttaaattat aaacatatca aaatcaattc atattagatt aaaatataat cttacttatt
     1981 caaaatttct ttacataacg cttatttact ttgacgattt aaaacatctt ccctattttt
     2041 tattaaattt tataataata gtcctattaa cgcaaatact ataaaaagag tttaacttta
     2101 tccattaaat aaatttaaat taaaacatat agaaatggaa ggagaacaat ttatgataaa
     2161 actaatcggt atattgatag ttgtaattgg atttatactt aaaattgaca cattatttac
     2221 tgtattatta gcaggaatgg caacaggaat tgttgcagga ttagatttta atcaaatctt
     2281 tacaatctta ggagattctt ttgtctcaaa cagaggtgta tcattattca tattaacttt
     2341 gccagtaatc ggtgtattag aaagatatgg tttaaaacaa agagctgttt ctttaataga
     2401 aaaattaaaa agactcacaa caggaaaagt acttactata tacatgatag ctagacaaat
     2461 agctggtgct ctatcaatca gaatgagtgg gcatcctcaa tttgtaagac cacttgttaa
     2521 tcctatggca caagctgctg gtttaagtaa tagtgatgaa ctaaaagaat cggatgaaga
     2581 agccataaaa gcattgtctg ccgcgtcaga aaactatgga aacttttatg gtcaaaacct
     2641 atttgcaggt agtagtggag tgttacttat agcatctact ctcactcaat ttggatacaa
     2701 tgtaactggt cttaatattg taaaagctaa tattattatg gcagtaatag cacttgtagt
     2761 agctaccatc cagtttacct tatatgacaa aaagttaaat aatagtcata aaaaatagat
     2821 ttatttagga ggaataaaaa tgcaaaattt tataaatata tcattagaaa ttttttacgc
     2881 actaatggga tttttaatga ttgtcatagc atataagtct tttactacca taaacaacaa
     2941 taaaaaatat ggtacatcat tattttggat acttatatca ttgccattca tatttggtag
     3001 attaattcca gctaatataa tcggaataat attaatatta tctagtttat taacactttc
     3061 taaacaagtt atatttgcaa agtatgaaga accaaatgag aattttggaa aagaacatgc
     3121 agataaactt aaaaacaaaa tatttatacc atcattaata ttagcatttg ctgcagtagt
     3181 tgtggctatg agcctttcta attttgctaa ttcttcacaa tttgcaatag gtgtaggttc
     3241 aataattgca ttaatatcag cccttataat aactaaggca aaacctgcta catcagttca
     3301 agatggttca agattacttc aacaaatggg tcctgctagt atgttaccac aacttttagt
     3361 tgcattggga gctttgttta ctcaggctgg agtcggcgaa gttatttcaa ccatgatatc
     3421 tggtgtagtc cctgctgata gcagattatt tggtgttata gcttatgtat taggtatggt
     3481 tatatttacc atgataatgg gaaatgcatt tgctgcattt tcagtcataa cggcaggaat
     3541 tggtattcct tttgtattgt ctcagggtgg aaatcctgct ataattggag cattagcatt
     3601 aacagcagga tattgtggaa ctctacttac tccaatggct gctaatttta atatagttcc
     3661 agcagcctta ctagaatgta aaaatgatta tattgttata aaatatcaag ctccagttgc
     3721 tttggtatta attatagccc acatattagt aatgtatttt ttaggatttt aatataatta
     3781 ggaggtaaaa taatgaaaat tttgttaaca ggatttgacc catttggtgg agaaccaata
     3841 aacccggctc aagaagcagt tgaaagggtc aataataata taaatggtgc agaaatcata
     3901 aagataacta taccaacagt tatgacaaag tctgttgaag ctatagataa agctattcaa
     3961 aagcacaatc cagatatagt aatatcggtt ggacaagctg gaggtagatt tgacattaca
     4021 cctgagagag ttgctataaa tatagatgat tttagaataa aagataatga aggtaaccag
     4081 gttatagata ctgttataaa agaggatggt gaacctgcat atttttcaaa attacctgta
     4141 aaagccatgg taaaacatat gaatgaaaat aaaattccag ctagtgtttc aaacactgca
     4201 gggacatttg tttgtaatca tgtgatgtat ggaatccttt atatgataga caagaaatat
     4261 cctaatataa aaggtggatt tatacacatc ccatatatga cttcacaagt aatagataaa
     4321 aaaaatacac catttatgtc tttagaagaa atagtaaaag gtttagaatt ggctatagaa
     4381 gcttgtatta tatacaagga agatgtaaag gaaattggtg gcgaaatttc ataataaatt
     4441 ttttagtatt tttataaatt aaaaatacta actattaatt taaatataga ctgtgagtag
     4501 attattcaaa caattttact cacagtcttt ttatagtatc tacagataca aaattaaggt
     4561 ctattcctct ctccccactc acacattgca tctaaaattg gaatcagaga ttttcccctt
     4621 tctgataagc tatattctac cttaggaggt atttgaggat attcagtacg aataatcaag
     4681 ttatctgctt ctaattcttt taatgataaa ctcaaagttt tataggagat agtatttata
     4741 taacgtttta atgcattata tcttacaact tcaaattcta caagacagta aagaattatc
     4801 attttatatt taccactaat cagtgaaagt gtataactaa atcctgtttc acttaaatct
     4861 gtatttgata tacagtctat actcatatat tacactctcc ttttggttag tattgaacaa
     4921 aaatgtgcgt acttgttttt agaataattt ataataaaat tatagtgtaa gaataattga
     4981 aagtcaattt tataatagga ggtgtattta ctaaaaaagg agttatttta aataggattc
     5041 taagattaga tatttctata taaattgata atattcatga aaatcctatt ttataaaaaa
     5101 taatatctct taaaaaatct attaaataaa attcattgga ggaaatttat aatgaaagtt
     5161 ttattgataa acggtagccc aaaccaatat ggatgtactt atacagcact gaatgagatt
     5221 actaaagtat tgagtaaaca cgatattaaa acagaaatac tgtatttagg taaagaagca
     5281 atcccaggat gtattagttg cgcatcctgt tttgaaactg gaaaatgtat tctaaatgat
     5341 aaagttaatg aattgattga agatctcgat aatattgatg gtattattat tggttctcct
     5401 gtttactttt ctagtgcaac tggtcaatta acttcatttc ttgaccgtct atttttcata
     5461 gctggaagtc gtatggctac aaaattaggt gcttcagttg tgtcatgtag acgtggtggt
     5521 gcaagtgcaa catttgacca actaaataaa tatttttcaa tcagcaatat gcctatagta
     5581 tcatcacagt attggaatca ggtacatggc tttactccag aggatgttat gaaagatgaa
     5641 gaaggattac aaactatgcg aactctagga gaaaatatgg catggcttct taaatgtata
     5701 tcagcaggta aaaaagcggg aattaaagaa ccacaatatg aagaaacaat tatgactaat
     5761 tttataaaat aaataaaaaa atgaagtaat attaattaaa acactaatct ataaataagc
     5821 ataaatatag gataaaaagc aataaaacag aggtatgaat tttatattaa acctctgttt
     5881 tattattcta ttaataatca aaccctatat cctatcatat atttctagat agattataat
     5941 ataatattct aatgttattg gaattacaat aactgaattt ctgttcataa ttttaaatat
     6001 tctacaaatc tcatctaaat aacaatttta attgacctaa aacaatcctc atattattca
     6061 ttttgtatta aatatcactt acaatcaaaa gccatttatt aagtatattc ctaagatata
     6121 caatatatat acatggattg gatagtataa ataaaataaa tacttcatac tcttcccttt
     6181 ttctccattg taaagcaaca ttaaaggtag agaagcaatc atcatccatt ggtaattttg
     6241 taaaatagaa ttttttaaac tataatctcc atttgacatt gctgtaaata taaatataca
     6301 cattaaaaca taacaaatac ttaaactgaa ctttttacct ctacacaaat aaaaaataat
     6361 cccaagtata atccaaactg gcccaccttc taccaaaaat ggtactggta ccaatatcat
     6421 aaatagaata ataatcttat tagtggcttt aaaaagtaaa gttactgtaa atattcctaa
     6481 aactatggga ataattatca tcaataatcc tataataaaa tatttaattt ctttctcttt
     6541 tctaaatttc tttataaact ctattgcttg taaataaatt gctattaaaa ataatgttga
     6601 aaaaatgtta tttataatta taactccttc tggatgtgaa aatacattat taattatttg
     6661 atttcctata gccataataa cagaccaaat atacaatcta cttatatatt tttttctgtt
     6721 actagtgtaa caaaatcctt caacaaccat aaatataaat agtggtgctg atattctgcc
     6781 tacccaatga aaccaaattg gtatttgcat tgtttgtggc ataaatgctg ctatatggtc
     6841 aaaagtcata aatattaatg ctagtacctt aatagtaaac ccacttattc ctttttttaa
     6901 aaaatccata tcatatctcc taattttgat ttatctctat aataatttct gtacctattc
     6961 caatttcact atttaaataa attttacctt tatgaatctc tattatttct ttagaaatag
     7021 ccataccaag acctgaacct ttatgcatct cacctgtatt agtaccccta tagtattttt
     7081 taaaaatatg tttcaaatca tttttgctta ttccaactcc actatctttt attataattt
     7141 ctatattatc tttttttaca atttttacac ttatcaaagt tccttcgcta ttatgaacta
     7201 ttgaattaaa tataagattg gttatagctc ttctaaataa gattgaatct acatatactt
     7261 caattaaatc ttcattgctt tcaaactcaa tattcctatt tttatatcta ttgtcattta
     7321 aaatatcaat tattatattt ctgactaaac cgactaaatt tacttttttc ttgtccaaaa
     7381 ctatagtatt attttttaat cgagtagata aatttaaatc atcaactaaa tcttttatat
     7441 acttagactt attatatata atttctgcat actctcgtat ttcatcttct gaaaactcat
     7501 aatctttgtc attaattatc tctgcatacc cttgtataga tgctagaggt gtctttatat
     7561 catgtgttat atttgccagc cattcttctc tcaactcttc gttttctttt ctctcaactt
     7621 catttactct taaagtatca gctaacatgt ttatattttt aaaaacttct tcatatatac
     7681 ctctgtcctt aagatataaa ctataatttc cattagccat agtctcaata ctccatagta
     7741 cacttgatat tggttttgta agttttctac taaataaata tcctacacct aaagctacca
     7801 tgccatcaat tactagtatt ataatgataa ttttatttaa agttttttta gtgttatttt
     7861 gagagtaggt taaaattatt cttgatacat ctctactagg tatccctact attatgttta
     7921 gatgtttttt gtttaaatat ttttctagga caaaattaac atactctgtt tctatatact
     7981 tgtaattatt taccatttga aatggtgtat atttttgggg agtatccttt ggcacattta
     8041 ctccaaaaac ctcttctcct aaatcattta aaacctgtat ccaggaattt gatttttcta
     8101 atttgtcagc tccaattttg gatagtttaa gttctccatc tttttcatat aaatcttttt
     8161 caaaagaacg tgcaaattct tcaggattat ttctagaatc tacaactttt aaaaaattat
     8221 cagttgaaat aacatacaat atagatataa tatttataat tactactgat atgactacaa
     8281 acacaattgt aaatataaaa tttctagtaa tcttccactt catattctaa tcttccttta
     8341 ctgacaattt atatccaaga ccttttattg tcagaatata ttcaggtttt gaaggattgt
     8401 cctctaattt ttccctaatt tttcttatat gaaccattat agtattgtca aacccaacat
     8461 aatcttctcc ccacacttta tcccatagtt tttctttact tataatctga ttttgattat
     8521 ttgcaaataa agataggatt tttaattcct ttgcagacaa tcctatagac tttccatctt
     8581 ttataagttc tgccctactt tcatttaata tatacgggcc aaatgatata gttttttctt
     8641 cattattatc tgaatctgta ttttcatttt gagaatcact aaaataactt aatcttctca
     8701 aatgagcttt aaccctaaaa gctacttcct taggactaaa aggttttgtg acataatcat
     8761 ctcctccaat tgctagtcca agtaatttat ctaattcttc agttttagct gataaaaata
     8821 tgattggaga attggaggtt tttcttattt ctttacaaat atcataacct tcaccatctg
     8881 gtaacataat gtctaatata atcaaatcag gattaatatt tttaaatact tctaatcctt
     8941 cttttctagt ttttgcagta tatatattac taagaccctc tttttttagg acagtttcta
     9001 aaagctttaa tatttctact tcatcatcta ttattaaaac acggttttcc ataaataacc
     9061 tcctataata atttacctat atattagcat atattttatc taaaattcat atatcttatt
     9121 ttaaattaaa ctaagatata aataaaatta ctattatctt tagttaaaat cttttgcttg
     9181 atgtaaaatt tttatatgtt attttggtta acactatcat taatataatt gagattacta
     9241 tagaaaaacc tatcaaaata ctaggtacat tatatctaac aatttgttga ctcatcataa
     9301 tccaatttgg agtcactgac ataaatttta tagctttatc tggtataaaa cctacactaa
     9361 agtatggaat tgccattatc agtccaccta gtataaatgg gattacagca gatttaaata
     9421 tagatgaaag tgttaaacct atttgtgcaa atacaaaaga agcaaaaata gtagtcaata
     9481 taacaattat atacatttgt attactgtaa gatttaaact actatttcca aagtaccata
     9541 agttatgaat cggttcattt aaatttttaa aatcaaaaaa actaaagcct ctaattccta
     9601 ctaacaatat aaaagaaata ttaataatgg ataaaattaa accattagca actaattttg
     9661 ataatactac tgattttttc ccacttttag ttgtatttat taaacctgtc atattggaat
     9721 catattcttt aatgtaattt ccagaagtta ttataaacat tatcaaacct attagaggta
     9781 ttgagccttc tatcttgtaa aatatatctg cataagtatc taaaacatca aactttctaa
     9841 ttagaacaaa tccaaaaaat agtaaaaaca accaaattat ccaaacactc tttgatttta
     9901 atatttttat catttcaatt ttaactaaat acattatttc tactacgcct cccttgcatc
     9961 ttccaagtca aaataaaaca tatatacatc ctcgaatttt gcttgaactg gttgtatatt
    10021 atctccaatt ggaatatcct ctgaaacaat tctaagtact attgaatcaa tatcactttg
    10081 aatgcttaca accttatatt tagattgtat atcatcaact tcacattcat ttttaacttg
    10141 aacattatat actttatttt ccatgtggct taatatttct ttgtgtgttc ctttcattag
    10201 aagtttgcca tctttaatca ttattgtttc ctttgcaact gattctatat cggaaattat
    10261 atgagtagaa agtactatta ttttatttct agatattttt gctattaaat ttctaaatct
    10321 agctctttcc tgtgggtcaa gacctgctgt tggctcatca aggactatta tcttagggtc
    10381 gtttaataaa acttgtgcta taccaactct tctcttcata cctcccgaaa attttcctat
    10441 ggacttatct ctcacatcat aaagtcctac taaatctaat agttcttcta tcttactact
    10501 taaatatttt ccctttaaac cttttaaagc tccaatatac tgtaaaaatt cttttgctgt
    10561 aaaattttta taaactccaa attcttgtgg caaatatccc aaaatgtttc tataatcatc
    10621 atccatttta aatatatctt caccattata aaatatctga ccttcatcag gttttatcaa
    10681 tgttgttatt tgtttcatta aagtagattt tcctgctcca tttggtccta aaagaccata
    10741 aactccattt tccagagtta ctgtaatctt gtcgtttgct acttttttac catatatttt
    10801 tgaaagattt tttatttcta atttattcat cttaactctc ctttatttac ttatataatc
    10861 cgactttatt attataaaac aaaatgacat agcacctata aatatagcca ccaaaactcc
    10921 tattaataga ttaacaatat ctatgtgtat tttaaatatt ataatctctc ctaaataatt
    10981 tcctattatt ttattaaatc cgaatatcaa atcataataa tttacagtag aaatagctaa
    11041 aagtaaattt ttaggtaata tgtgaattac tgatattatc ttagttataa ctatagtaaa
    11101 tataaaaaaa cttattgatg ttattgaaga tttacttata aatgaaccta atagggctat
    11161 catagccaat ccttcaaaca ttaaaaactc gatacctata tttgatatta cataatttat
    11221 tatgctcgaa ttgcatttca aagtagctat gttatctact attctaaaag cttctaaatc
    11281 tccattaatt ggcatacctt gttgcataca tgttgtaatg aatattccaa ttaaataaac
    11341 agaataaatt gttaatggta ctaagaaagc aataactatt tttgagttta atgccttctt
    11401 cttttctttt gatgatagaa tgatatctct tactgaaaaa accagttcat ctacataaat
    11461 atttgatata attataacaa tgataattaa cattcctaca tttataagtg aatttgtagc
    11521 tctatagttg aacaccttcc aaaaactaac atctttatat tcattaatta ttaaattata
    11581 aagtttgtta gttgatattg atttaatttt tttagaaaat acatccatat ctttttgact
    11641 tgaaagttgt tttaaaacat taatcttatt ttgaaactta taattaccta tctcttcact
    11701 atttctcgta tcttctatac gccctctttc tttatctata taataatttt cagtttctaa
    11761 aacaggtttg acaaatatgt tgattgatag tattaatatt aatattccta gagatataaa
    11821 catactttta gatttaatca atttttttat ttcccaattt accaatatac taagcctcct
    11881 aaatcatttt gactacactt atatattaaa acttaaatct tatatcaata taatcttaac
    11941 cttaaataaa gcttaaatta tttactttat tgaaactcat caaaaatatg cttttaaatt
    12001 taattttttt taaaatagtc taaaatatat ttatttttta ttgtaatctt ttagtttatc
    12061 ttttttataa gatacctgct atactttttc taataagatt aagtttagta gttatatgag
    12121 aaatacagat atttatataa agtttagaat aaacctttta acatctatag gcatgtttat
    12181 cattacagtt gtatttatta tttttggtat ttttattgag tgaaaatttt atctttgtct
    12241 aaactgtaat cattgtttag atttaagtaa tgagtttcta aagaatggtt cttattgtcc
    12301 tcattatgga aagattatta agtagtaatt cttttgcaca ttttatttag tgttaattaa
    12361 taaaatttgc tctaggctta tttctatact tcttgttaag ttataaaagt tttaaacatg
    12421 ttaaaaagat ataaaaaatt attctagaca attctctata tcttttggtg tttataaata
    12481 cttt
//
LOCUS       DBGJFK010000098        12280 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.102, whole genome shotgun sequence.
ACCESSION   DBGJFK010000098 DBGJFK010000000
VERSION     DBGJFK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12280
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.102"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            1011..1706
                     /gene="cas6"
                     /locus_tag="ACOIAP_003297"
     CDS             1011..1706
                     /gene="cas6"
                     /locus_tag="ACOIAP_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HGZ2640172.1"
                     /translation="MIKCLEMSVKVYLLENISLDNTSKEIRKLIDDTLIIEEKYKEFH
                     NKAGFKNYSFNLLYPLEKDKVYKKDCIYTFIIRTVDSELGMYFMNNLKNQYSDKIKVI
                     TMSKKVIPKKHIESIYSVTPIIAKFEDGYWRSNKTVEDLEKRIRENLIKKYNEFTNSK
                     IDEDFELFQVIKFINRKPISTKYKNISLLGDKISFKVSENDMAQEIANFALGVGVGEI
                     NSRGFGFVNYRWL"
     gene            1718..3457
                     /locus_tag="ACOIAP_003298"
     CDS             1718..3457
                     /locus_tag="ACOIAP_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cse4"
                     /protein_id="HGZ2640173.1"
                     /translation="MLKDCLEIFEKEYKSLGNRLITDSYVLSYGTYILVKNFSNIDIL
                     EVSKNNVDSTEDIYHKFCELDYLSKLVSIDKSVDSKKIIHSNNYLSFFVKKENLRPDK
                     NNNVKLTEEIIDNYYDALLNPRIKYKSDKRKKEIYDSIENKYGKVDENKLNKIRLWIK
                     TNIFDLVESVKKDKNYLKIFFDEKIELYNDENQKYLYPNIYNKNDFNVIIDGKNYGLP
                     NDNMQLNEKKPFLKLKTRIRNSTPYLISDDEVLLQKAFFDYLMNKAANGEEVVYISSE
                     KGIHRKTDIPNEFSGYILRIKKGKELEIHDFDTVVNLNTKIKRINVECIIPIEYERHN
                     LKPNLEIGYINNLIKLEKTIDTIFFNKFMCNSYFKEIKNINLSDLVLRDILIRHREGL
                     YTWFYKGRDNIVKQTFSNYSMGIIENSIKNNNYIRAKEQYNLRIAIINYFHGGSNMAD
                     KIKVISESLFEKINSIKTKCIQSDEEYYFAVGQLASYFISKNKSKNKNHSLINPILNA
                     QNRKKIMLEIEKLFKKYNYDISYDNNRRFKNLYSMIVGYEVEEKKVNRDLLIGGYLYY
                     SLIYTKSEENENE"
     gene            3450..4439
                     /locus_tag="ACOIAP_003299"
     CDS             3450..4439
                     /locus_tag="ACOIAP_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I CRISPR-associated protein Cas7"
                     /protein_id="HGZ2640174.1"
                     /translation="MNRRVYGVLGIKSIMSNWNADFSGYPKTTSTGEVFGSDKALKFP
                     MKKMWENEGEKVLYVKSLKIDESKKGEIKIRPKSLKERYEELFDIEELKLEKNQQKVL
                     ENLFKAIDVKNFGATFAEEGNNIGIMGAVQIGQGFNKYEDINVEEQQILSPFRDPRAK
                     DKKKSTNEEEKEDANSTTLGKKIVSDEAHYFYPFSINPKAYEVFVNMGVTDGYTKNDY
                     KKFKEAALVSATAFNTNSKLGCENEFALFVETDEELYLPDLAQYITFEKREKSKDLIC
                     INIIHLIAELKDDIKSVEIYYNPYKIEIKPFKDEILPKIDKVKFMNIFTRKEV"
     gene            4441..5181
                     /gene="cas5b"
                     /locus_tag="ACOIAP_003300"
     CDS             4441..5181
                     /gene="cas5b"
                     /locus_tag="ACOIAP_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5b"
                     /protein_id="HGZ2640175.1"
                     /translation="MEVLKFNLSGKTAFFKKPDVNSIIYFTYGNIHKIALMGILGACL
                     GLGGYNQQSKEDEYPEFYSLLKDIKMSIVPKHEFGYINKKVHIFNNSVGYASKEEGGN
                     LIIKEQWLENVSWDIYIQLEDSTTSRELKRRFLSNKFVYIPYLGKNDHIANISEIEII
                     TDFYKTEDINRVDSFFIREDFEFEKSYFDDNDDYEEPFKYQEKLPYRLHRMTNQYILE
                     TIIFTNMSVKLINKKEVYQVKGLNLIFI"
     gene            5205..7763
                     /locus_tag="ACOIAP_003301"
     CDS             5205..7763
                     /locus_tag="ACOIAP_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HGZ2640176.1"
                     /translation="MYFKKVELFDISNNINNCKNIYAHINKDRKPETLKEHSDLSYSY
                     LMKLCVKKDLSSCLERIENKFFKKDSFLSKNFYREIILNMVYMHDIGKINSSFQFVKM
                     QNKNFKKISLRYTKHSFISSMLYFDYYFEKLKKYDFEEKKILSLFLMINTYTISKHHG
                     VLKSFKEFLFLFKDEFINIKENFKDLFKNNYNLELKSVPKTIEKMVRGVEGYLDDSHI
                     KDNLAIDLYIYSKLMFSIVTSCDFYATSEYNSGNSIDGFGTIDNYNKYYDVLKKSEIY
                     KGMKKYREYLNNNSECPYKENDINRLRTEMSIEAEDAITHNTRKRIFYLEAPTGSGKT
                     VTSINLALKSIELNQSLKKIFYIFPFNTLVEQTKDVFINEIFNSVKDIQKDVVVINSI
                     TPIQTEDKEEDNKNVEYCVTKQEIDYDKSLLNRQFLHYPIVLTTNIGFFNYLFGVSRE
                     ECFPLIHMINSVIILDEIQNYKNEIWKEIILFLEKYADILNIKFIIMSATLPRLNKLG
                     CNDDNFAYLVKNREKFFKNHLFKDRVNISFEMLNSEINDIEEISEKVIEEAEIYNKIL
                     IEFIKKSSALEFYKNIKEKLKYKLEDVFLLTGDDNKLERKKIINKIKDMNSVILVATQ
                     VVEAGVDIDMDLGFKDISTIDSDEQFLGRINRSCKKLNSKVYFFNLDDASKIYKKDVR
                     KERHLTLNEESNRKIILDKDFEKYYDKIIARIEENKHKHNDKNIEVFIKDIVGNLNFT
                     EVKKWMALIPDLKEYTIFLNTIVKDESGNMIVGSDVWYEYISLLKNDNVEYSEKRVKM
                     SEIMEKLDYFTYKVQKFDNSFNDLVGDIFYIDDGSKYFTEGKFDRSKFNQNEFL"
     repeat_region   7953..10551
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7953..7982
                     /rpt_unit_seq="gttaaacagtaacatgagatgtatttaaat"
     gene            10636..11130
                     /locus_tag="ACOIAP_003302"
     CDS             10636..11130
                     /locus_tag="ACOIAP_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HGZ2640177.1"
                     /translation="MKITGTLINYYFHCKRQCWLLGNRINLEENSEDVKIGRLLHELK
                     EEKSKYKEIAIENIKIDKLTREYLVEVKKSDADIEAVKWQVLLYLKKLKEKGIVRKGK
                     IEFIEKNKTNKKIVFVDLSEVSEEQLISIEREIVNLINSDKAPCPDLKKGCKKCAYYE
                     YCYI"
     gene            11156..12163
                     /gene="cas1b"
                     /locus_tag="ACOIAP_003303"
     CDS             11156..12163
                     /gene="cas1b"
                     /locus_tag="ACOIAP_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1b"
                     /protein_id="HGZ2640178.1"
                     /translation="MLILGKTKYITSMGELTRKDNSICFRKNGRNVYIPVENTSEIFC
                     LNEVSLNSKLLDFLSRANIVVHFFNYYGGYSGTFYPKEYLISGKVTVAQVKTFEDRRE
                     EIAKSIVNGIRINAINTLSHYYKHGNSEIQPLLSHLKKDSINKLEKSNNIKEILSVEG
                     DIWQTFYTSFKYILREEFIFNKRVKRPPDNPLNAMISFGNSILYSKTVTAIYNTHLNQ
                     SVSFLHEPSESRFSLSLDLSENFKHVITFKTIFDLVNNRKINIEKHFDKNLNYCVLND
                     EGKQIFINSLEERLESVKEHPKLKRKVSLKTCIKLDAYKMLKCIMEEKSFIPYNIKDG
                     L"
BASE COUNT         5169 a         1062 c         1841 g         4208 t
ORIGIN      
        1 taagagtgaa tatagcaaag agaagcaata gtattttaaa ctttgtctct cttatttttt
       61 gaaaactaac attaaaacat aaggtataaa taatattatc atataaatga aaacaaattt
      121 gaatttttct ctggtcgatg tatatagtaa gtttgttgat aggagaaaaa ttattattga
      181 taatatacat gcatagaaag gaaatggtat ataatatttt cttaagtttc ttttttaggc
      241 atttctattg gcattttagg ctatagtact aaatacatta accaacaaaa taatgaaata
      301 aatatatata tagaaaactt aattttcgtg ggaagaaaaa aagcaataat agcaagtatt
      361 attagagaat aacgaataat acgagtaaca tttctttctt tttctatgat agttaaatcc
      421 cagtgatttt ttataaattc aaggtctttt tcttgactct gattcattta atcatttcct
      481 gttaatagta taattttaaa gctattactt tgttttattt taacatattt atacactaaa
      541 gtgaatttta tgattagatt tatttaatta tttctgaatt aaaacttatt agaattctct
      601 attttgataa tttcaaactc tattgattgt atgataattg aaactatagg atatgtagga
      661 taacaagttt caaagtagtt aaaataaaaa agataatgat attattaatt tagaataaat
      721 tttatatatt atatttaatt atttacttgt tttaaatttt attaacttaa aaaatgtaag
      781 aaatttatta tcaataatct aaatatagaa attaaaaatg ataaagagat tgtaattata
      841 tttttttgaa actttgtgat tttatttgtc gaataaaaaa taaaaaaatt taaaggaaaa
      901 agttaaaaaa taaagaattt tataactata aattatattt tagagtttat tgttattaaa
      961 tagatgaaaa aatcctaatg tggattatca gaaaatgagg aggttgttaa ttgataaaat
     1021 gtcttgaaat gtctgtaaaa gtgtatcttc ttgaaaatat ttctttagat aatacatcaa
     1081 aagaaatacg taaattaata gatgatacat taattataga agaaaaatat aaggaatttc
     1141 ataataaagc tggatttaag aattattctt ttaatttatt atatccatta gaaaaagata
     1201 aggtttataa gaaggattgt atatatactt ttattattag aactgtagat agtgaattag
     1261 gaatgtattt tatgaataat ttaaaaaatc agtattctga taaaataaag gttattacaa
     1321 tgagtaaaaa agtgatccct aaaaaacata tagaaagtat ttactctgtc actccaataa
     1381 tagctaaatt tgaggatggg tattggagaa gtaataaaac agtagaagat ttagaaaaaa
     1441 gaatcagaga aaatttaata aaaaaatata atgaatttac taacagtaaa atagatgaag
     1501 attttgaatt atttcaagtt attaaattta taaataggaa acctatttct actaaatata
     1561 agaatatatc tttacttggt gataaaataa gttttaaagt atcagaaaat gatatggctc
     1621 aggaaattgc aaattttgca cttggagttg gagtcggaga aattaattct cgtggatttg
     1681 gttttgtaaa ctatagatgg ttataggagg tgaaaacttg ttaaaggatt gtttagagat
     1741 ttttgaaaaa gaatacaaat ctttaggaaa tagattgata actgatagct atgtcctatc
     1801 ctatggaaca tatatattgg tgaaaaattt ttcgaatata gatatattag aagtttctaa
     1861 aaataatgtg gatagtacag aagatatata ccataaattt tgtgaactgg attatttatc
     1921 aaaactggtg tctatagata aatcagttga ttccaaaaaa ataatacata gtaataatta
     1981 tctttcattt tttgtaaaaa aggaaaactt aagacctgat aaaaataata atgtaaaact
     2041 tacagaagaa attatagata attattatga tgctttgtta aacccaagaa ttaaatataa
     2101 gtctgataaa agaaaaaaag aaatctatga ttcaatagaa aataaatatg gtaaagtgga
     2161 tgaaaataaa ttaaataaaa taagactatg gataaaaaca aatatatttg atttagttga
     2221 atctgttaaa aaagataaaa attatttaaa aatatttttt gatgaaaaaa tagaattata
     2281 caatgatgaa aaccaaaaat atttatatcc aaatatatat aataaaaatg atttcaatgt
     2341 aattattgat ggtaaaaact atgggttacc aaacgataat atgcaattaa atgaaaaaaa
     2401 gccatttttg aaattaaaaa caaggattag aaattcaact ccttatttga ttagtgatga
     2461 tgaagttttg ttacagaaag ctttttttga ttatctaatg aataaagcag cgaatggaga
     2521 agaagtagta tatataagta gcgaaaaggg aattcataga aaaactgata taccaaatga
     2581 atttagtggt tatatactga gaataaaaaa gggtaaagaa ttagaaatac atgattttga
     2641 tactgtggta aatttaaaca ctaaaataaa aagaataaat gtagaatgta taataccaat
     2701 agaatatgaa agacataatt taaaaccaaa tttagagata ggatatatta ataatcttat
     2761 aaaattggaa aaaacgattg atactatatt ctttaataaa tttatgtgca atagttattt
     2821 taaagaaatt aaaaatataa acttaagtga tttagttcta agggatatac ttattagaca
     2881 tagagaaggt ttatatacct ggttttataa agggagagat aatatagtaa agcaaacttt
     2941 ttcaaactat tctatgggta taattgaaaa ttctataaaa aacaataact acataagagc
     3001 aaaggagcaa tataatttaa gaatagctat aataaattat tttcatggag gaagtaatat
     3061 ggcagataaa ataaaagtta ttagtgaatc tttatttgaa aaaataaatt ctataaaaac
     3121 gaaatgtata caaagtgatg aagaatatta ttttgcagtt gggcaattag catcatattt
     3181 tatatctaaa aataagtcaa aaaataaaaa ccattctctg attaatccta tactaaatgc
     3241 acaaaataga aaaaaaatca tgttagagat agaaaaatta tttaaaaaat ataattatga
     3301 tataagttat gacaacaata ggcgatttaa gaatctatat tctatgattg taggatatga
     3361 ggtagaagaa aaaaaagtta atagagattt attaattggt ggatatctat attacagttt
     3421 aatatacaca aaaagtgagg agaatgaaaa tgaatagaag agtatatgga gtattaggta
     3481 taaaatctat aatgtcaaac tggaatgctg atttttctgg atatccaaag acgacatcaa
     3541 caggagaagt ttttgggagt gataaagcac ttaagtttcc catgaaaaaa atgtgggaaa
     3601 atgaaggtga aaaagtttta tatgttaaat cattaaaaat agatgaatct aagaaaggag
     3661 aaataaaaat tagaccaaaa tcattaaaag agagatatga agaattgttt gatatagagg
     3721 aactaaaact agaaaagaat caacaaaaag tactggaaaa tctatttaag gctattgatg
     3781 ttaaaaattt tggtgcaaca tttgcagaag aaggaaataa tataggaatt atgggcgcag
     3841 tacaaattgg acaaggattt aataagtatg aagatattaa tgttgaagaa caacaaatat
     3901 tatccccatt tagggatcca agagcaaaag ataagaaaaa gtcaacaaat gaagaagaaa
     3961 aagaagatgc aaattcaact acattaggaa aaaaaatagt aagtgatgag gctcattact
     4021 tttatccatt ttcaataaat ccaaaagctt atgaagtttt tgttaatatg ggtgtgactg
     4081 atggatatac taaaaatgat tataaaaaat ttaaagaagc tgctttagta agtgcaactg
     4141 cattcaatac aaattcaaag cttggttgcg aaaatgaatt tgcattattt gttgaaactg
     4201 atgaagagtt atacctacca gatctggcac aatatataac ttttgaaaag agagaaaaat
     4261 caaaagattt aatttgtata aatataattc atcttatagc agaattaaaa gatgatataa
     4321 agagcgttga gatatattat aacccatata aaatagaaat aaagcctttt aaagatgaaa
     4381 tattacctaa gatagataaa gttaaattta tgaacatatt tacaagaaaa gaggtataat
     4441 atggaggttt tgaaatttaa cttaagtgga aaaactgctt tttttaaaaa accagatgta
     4501 aatagcataa tttattttac gtatggaaac atacataaaa ttgcacttat gggtatttta
     4561 ggagcttgtt taggacttgg tggatataat caacagagta aggaggatga gtatccagaa
     4621 ttctactctt tacttaagga tataaaaatg tcaatagttc caaagcatga atttggatat
     4681 ataaataaaa aagtccatat atttaataat tctgtaggat atgcatcaaa agaagaaggt
     4741 ggaaatttaa taataaaaga acagtggctt gaaaatgtta gttgggatat atatatacaa
     4801 ttagaagatt caactacaag tagagagctt aaaagaagat ttttatctaa taaatttgta
     4861 tatatacctt acttaggcaa aaatgatcat atagctaata taagtgaaat agagataatt
     4921 actgattttt acaaaacaga agatattaac agagtagaca gtttctttat aagagaggat
     4981 tttgagtttg aaaaatctta ttttgatgat aatgatgatt atgaagagcc atttaaatat
     5041 caggaaaaac ttccttatag actgcaccga atgactaatc aatatatttt ggaaactatc
     5101 atatttacta atatgtcagt taaattgatt aataaaaaag aggtatatca agtaaagggt
     5161 ttaaatttaa tctttattta aatttatagg tttaggagaa ttatatgtac tttaaaaaag
     5221 ttgagttgtt tgatataagt aataatataa ataattgcaa aaatatttat gctcatataa
     5281 ataaagacag gaagccagaa actttaaaag aacattcaga cttatcatac tcatatctta
     5341 tgaaattatg tgtaaaaaaa gatttaagct cttgcctaga gagaatagag aataaatttt
     5401 ttaaaaaaga ttctttttta agtaagaatt tttatagaga gattatcttg aatatggttt
     5461 atatgcatga tataggtaag attaattctt catttcagtt tgtaaaaatg caaaataaaa
     5521 attttaaaaa aatttcactt agatatacta aacattcttt tatctcttca atgctatatt
     5581 ttgattacta ttttgaaaag cttaaaaaat atgattttga agaaaaaaaa atattgagtt
     5641 tatttttgat gataaataca tatacaatat caaaacatca tggggttctg aagtcattta
     5701 aagaattttt atttttattt aaagatgagt ttataaacat taaagaaaat tttaaagatt
     5761 tatttaaaaa caattataat ttagagctta aatcagttcc caaaactata gaaaaaatgg
     5821 taagaggtgt agaagggtat ttagatgata gccatataaa ggataactta gctatagact
     5881 tatatatata ttcaaaattg atgttttcaa ttgttacatc ttgtgatttt tatgctacat
     5941 cagaatataa tagtggtaat tctatagatg gttttgggac aattgataat tataataagt
     6001 attatgatgt attaaaaaaa tctgaaatat ataaggggat gaaaaaatat agggaatact
     6061 taaataacaa tagtgaatgc ccatataaag agaatgatat aaacagattg agaacagaaa
     6121 tgagtataga agctgaagat gcaattacac ataatacgag aaaaagaata ttttatttag
     6181 aagcaccaac tggaagtgga aaaactgtta catctataaa tctagcactg aaatctatag
     6241 agttaaatca atctttaaaa aagatatttt atatatttcc atttaacaca ttagtagagc
     6301 aaacaaaaga tgtatttata aatgaaatat ttaattctgt taaagacata caaaaagatg
     6361 ttgtagttat aaattcaata acaccaatac aaacagaaga taaagaagaa gataataaaa
     6421 atgttgaata ttgtgttact aaacaagaaa ttgactatga taaatcattg ttaaatagac
     6481 aatttttaca ctatcctata gtacttacaa ctaatatagg tttttttaac tatttgtttg
     6541 gtgtatcaag agaagaatgt tttccattga tacatatgat aaatagtgta attatattag
     6601 atgaaataca aaattataaa aatgagatat ggaaagaaat tattttgttt ttagaaaaat
     6661 atgcagatat attaaatata aaatttatta taatgtctgc aactttacct agattaaata
     6721 aattaggatg taatgatgat aattttgcat atctagtaaa aaacagagaa aaatttttta
     6781 aaaatcacct ttttaaagat agagtaaaca taagttttga gatgttaaat tcagaaatta
     6841 atgatattga agaaatatca gaaaaggtta tagaagaagc agaaatatat aataagatac
     6901 tgatagagtt tataaagaaa tcatcagcac tagaatttta taaaaatatt aaagaaaaat
     6961 tgaagtataa gttagaagat gtttttttat taacaggtga tgataataaa ttagaaagaa
     7021 aaaaaataat aaataaaatt aaagatatga actctgtaat tttggttgct acacaagttg
     7081 tagaggctgg agtagatata gatatggatt tgggatttaa agatatatct acaattgatt
     7141 ctgatgaaca atttttggga agaataaata gatcttgtaa aaaattaaat tcaaaagtat
     7201 acttttttaa tttagatgat gcaagtaaga tatataagaa agatgttaga aaagagagac
     7261 atttaactct taatgaggaa agtaatagaa aaattatttt agataaagac tttgaaaagt
     7321 attatgataa aataatagcc agaatagaag aaaataagca taaacataat gacaagaata
     7381 tagaggtttt tataaaagat attgtgggaa atttgaattt tacagaggta aaaaaatgga
     7441 tggctttaat accagattta aaagagtata caatcttttt aaatactata gttaaagatg
     7501 aatctggaaa tatgattgta ggaagtgatg tatggtatga atatatatca ctactaaaaa
     7561 atgataatgt tgagtattct gaaaagaggg tgaaaatgtc tgaaattatg gaaaaactag
     7621 attattttac gtataaagtt cagaaatttg ataattcatt taatgattta gttggagata
     7681 ttttttatat tgatgatgga agtaagtatt ttacagaggg aaagtttgat agaagtaaat
     7741 ttaatcaaaa tgaatttcta taatgtattt agattatata gagaatattt atcccaagtt
     7801 aattaattag aattagttta aagctattga aatatagata ttttatatct tatatatatt
     7861 ttctaggatt agctgggata aaaaatctgt atattagtgt tttcagtgta tttaagggaa
     7921 ttatattttt aagaagtact gattttaaag tggttaaaca gtaacatgag atgtatttaa
     7981 atatgtttaa gtcagatggc tcaccaaatc aaatgtttgt taaacagtaa catgagatgt
     8041 atttaaattt tattgtagct gttataactt ctttatttgt attagttaaa cagtaacatg
     8101 agatgtattt aaattgattt attagaggaa aatagagaat taaatattaa gttaaacagt
     8161 aacatgagat gtatttaaat tattgctcta aatttagtag accaagttca atttctgtta
     8221 aacagtaaca tgagatgtat ttaaatttaa atgctttata aagtattaat tcattttgta
     8281 acgttaaaca gtaacatgag atgtatttaa attattaatc cttctattgg aaaatatcgt
     8341 cttcaagagt taaacagtaa catgagatgt atttaaatta tagttttgta gctctttcaa
     8401 gttcatctgc atttgttaaa cagtaacatg agatgtattt aaatatatat ctaaatggat
     8461 tattatatct aactccatct gttaaacagt aacatgagat gtatttaaat attttataat
     8521 ggtaaaaaag agttttacat agctggttaa acagtaacat gagatgtatt taaatttttg
     8581 aagtttagtt atatctgggt caccagtctg tgttaaacag taacatgaga tgtatttaaa
     8641 tcagcatcta aaccttctct tcttgcttcc tctgaagtta aacagtaaca tgagatgtat
     8701 ttaaatttaa aattcaattt agtaaatgaa gttaattctg gagttaaaca gtaacatgag
     8761 atgtatttaa atttttcttt tgcagcactt cctagaacat ctccatcagt taaacagtaa
     8821 catgagatgt atttaaattc aaatctaact gatgttcttt tattatcaaa aggttaaaca
     8881 gtaacatgag atgtatttaa attctttagc tttttctatt tcagcaatta tctctactgt
     8941 taaacagtaa catgagatgt atttaaatgg attatccaat ctttaatctt attaccatac
     9001 cattgttaaa cagtaacatg agatgtattt aaattatctc ttaaagcact atctaattca
     9061 acaatagttg gttaaacagt aacatgagat gtatttaaat tattgaactt agcatctaat
     9121 ttagtatttt tagtaggtta aacagtaaca tgagatgtat ttaaattaga ataaaaatta
     9181 cttgcagaat aaaaaatgtc ttcgttaaac agtaacatga gatgtattta aattagaaaa
     9241 aagtgtacat tgacaactga atatcccctg ttaaacagta acatgagatg tatttaaata
     9301 cacttatttt gattttattt attttaattt tttatgttaa acagtaacat gagatgtatt
     9361 taaattccat ctactttttt acttttagct ttttctttag tgttaaacag taacatgaga
     9421 tgtatttaaa tagtctgaag atgagcgaat gtgctatatc tgtaatagtt aaacagtaac
     9481 atgagatgta tttaaattta aatataataa atcgtaatgt acaaaaataa cttagttaaa
     9541 cagtaacatg agatgtattt aaattttctt gagttaattg aacccccatt tttaagctcc
     9601 gttaaacagt aacatgagat gtatttaaat ttttcttcta gctctttttt cttagccatt
     9661 ttaccagtta aacagtaaca tgagatgtat ttaaatatgt ttatacatga gtttagtgat
     9721 aggttcttgg tcgttaaaca gtaacatgag atgtatttaa ataaggcaag tgatttgcta
     9781 tttagaatag gtgtaaacgt taaacagtaa catgagatgt atttaaatat ttctttttgt
     9841 gaagtgttaa gagattgctc ttcgttaaac agtaacatga gatgtattta aatacagtag
     9901 ctattccaat ttcttctgct tgtggcatag ttaaacagta acatgagatg tatttaaatt
     9961 caaagatgcc cctctagctg gtttttgggt atctagttaa acagtaacat gagatgtatt
    10021 taaattgtgt tgagtcgtga tattgacttt ttcggaaacg ggttaaacag taacatgaga
    10081 tgtatttaaa tttgtagtcc ttccatttcc atcacacaaa aagcatgtta aacagtaaca
    10141 tgagatgtat ttaaattcta tgttatgtac atgattacct tgtttgagta ggttaaacag
    10201 taacatgaga tgtatttaaa ttaagagtct ctttgtatat caatttctct agtagatgtt
    10261 aaacagtaac atgagatgta tttaaattaa attattagtt ttaaaattta aagggggaaa
    10321 aaagttaaac agtaacatga gatgtattta aatgctaact taattacttg ttccacattt
    10381 gctaataccg ttaaacagta acatgagatg tatttaaata aatattcaat atagttttta
    10441 aatacacttt ccattgttaa acagtaacat gagatgtatt taaattcatt agtacttgtt
    10501 attccagtaa aagctacttt ggttaaacag taacataaga tgtatctaaa ttactctatc
    10561 ataaaatttt aatatattaa acaaactaat atgtgatata cttatgtata aataacaaaa
    10621 taaataggtg atgttatgaa aattacagga actttgataa attactattt ccattgtaaa
    10681 agacaatgct ggttgcttgg taatagaata aatttggaag aaaatagtga agatgtaaaa
    10741 ataggtagac ttcttcatga actaaaagaa gaaaaatcaa aatataaaga aattgcaatt
    10801 gaaaatataa aaatagacaa attaacaaga gaatatttag tagaggttaa aaagtctgat
    10861 gctgatatag aagctgttaa gtggcaagtt cttttatatt taaaaaagtt aaaagaaaag
    10921 ggaattgtaa gaaaagggaa aattgaattt atagaaaaaa ataaaactaa taaaaaaata
    10981 gtctttgtag atttgagtga agtatctgaa gaacagctta tatctataga aagagaaatt
    11041 gttaatttaa taaatagtga taaagcacca tgtcctgatt taaaaaaagg atgtaaaaaa
    11101 tgtgcctatt atgaatattg ttatatataa agaggtataa gaaacatata aggaggtgtt
    11161 aatattggga aagacaaaat atattacctc aatgggtgaa ctcacaagaa aagataattc
    11221 tatatgtttt agaaaaaatg gaaggaatgt atatatacca gtagaaaata ctagtgaaat
    11281 attctgtcta aatgaggtat ctttaaattc aaaattactg gattttttat caagagcaaa
    11341 tattgttgtt cattttttta attactatgg tggatatagt ggaacttttt atcctaaaga
    11401 atatttaata agtggaaaag taacagtagc acaggtaaaa acctttgaag atagaagaga
    11461 agaaatagca aaatccatag tcaatggtat aaggattaat gcaataaata cattatcgca
    11521 ttactataag catggaaatt cagaaataca accattatta tcacatctaa aaaaagattc
    11581 tataaacaag ttagaaaaat caaataatat aaaagaaata ttatcagttg aaggagatat
    11641 ttggcaaaca ttttatactt cctttaagta tattttaaga gaggaattta tttttaataa
    11701 aagagttaag agaccaccag ataatccctt aaacgcaatg atatcatttg gtaacagtat
    11761 tttatattct aaaactgtaa ctgctatata taatacacat ctaaatcaaa gtgtaagttt
    11821 tttacatgaa ccaagtgaaa gtagattttc tttaagtcta gatttaagtg aaaattttaa
    11881 acatgttata acttttaaaa ctatatttga tttagttaat aatagaaaaa taaatattga
    11941 aaaacatttt gataaaaatt tgaactactg tgttctaaat gatgaaggaa agcaaatttt
    12001 tataaattct ttagaagaaa gattagaatc agtcaaagaa catccaaaat taaaacgaaa
    12061 agtaagttta aaaacctgta taaaattaga tgcttacaaa atgttaaagt gtataatgga
    12121 agaaaaaagt tttattccat ataacataaa agacggatta taatttaaac ataaagtaag
    12181 tattttaata tagaactttg atatatataa gaatgataat tatgctatta taagtataca
    12241 taatatatta ttgaaataat ataagttttt agaagtattt
//
LOCUS       DBGJFK010000099        11948 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.103, whole genome shotgun sequence.
ACCESSION   DBGJFK010000099 DBGJFK010000000
VERSION     DBGJFK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11948
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.103"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(229..381)
                     /locus_tag="ACOIAP_003304"
     CDS             complement(229..381)
                     /locus_tag="ACOIAP_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HGZ2640179.1"
                     /translation="MATFIIAAIVVVLMALAVMYMIKNLKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(407..2563)
                     /gene="feoB"
                     /locus_tag="ACOIAP_003305"
     CDS             complement(407..2563)
                     /gene="feoB"
                     /locus_tag="ACOIAP_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HGZ2640180.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKEAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISNIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKVPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSIKGVLIHM
                     WDRGKAFIVKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVANAFAFMAF
                     NMLCAPCFAAIGSIKREMGSWKWTWITLGFQTLTAYIVALLINQVGSLVLGTGGSIAG
                     AIISVVIAVGVVFAVLTYSNRNMKKEKMGKLSYMKN"
     gene            complement(2666..2887)
                     /locus_tag="ACOIAP_003306"
     CDS             complement(2666..2887)
                     /locus_tag="ACOIAP_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGZ2640181.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEITVRDYELSIRKSDAEKIIVE"
     gene            complement(2900..3112)
                     /locus_tag="ACOIAP_003307"
     CDS             complement(2900..3112)
                     /locus_tag="ACOIAP_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGZ2640182.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(3433..6330)
                     /locus_tag="ACOIAP_003308"
     CDS             complement(3433..6330)
                     /locus_tag="ACOIAP_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HGZ2640183.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIKVGYCD
                     DYGIISSSKEHSYSGYGYDYLREISKYTRWEYEFIKGSWEECLDRLEKGEIDLLGPLQ
                     KDDERNKIFNFPKLSSGYEYSALYTDDSNNNMFYEDINSFNGMRVAVLRGNFHNIAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIIDAKGMKIVSKFSVEPFYFA
                     TAKDKPNLAKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEINFIKANPK
                     LTMVYDSEWSPVEYYDKKSNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMICGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYNSVESCLNAINEGKANLMVLSSYQFDELLRKGKSENLSVISVL
                     DTSYGMRIGVSNKTNPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLKRIAYTDSLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYMDVDKFKYINDMFGYDMGNNTLIHISDTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNSIYNKVQIFSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFVVYFQPKYRLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQE
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTSLIELELTETAVLDNIEGLLDTMNN
                     LKENGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(6656..7264)
                     /locus_tag="ACOIAP_003309"
     CDS             complement(6656..7264)
                     /locus_tag="ACOIAP_003309"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HGZ2640184.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFIAGYSVGA
                     TIAWRCSEDSLCDGIICCYGSRIRDYMDVIPKCPTLLVFAKYDSFDVNSISCQLSRKQ
                     NIQIEILDANHGFIDIYSKNYSDIQTKAFTVKEKSFLSKCLV"
     gene            complement(7524..8069)
                     /locus_tag="ACOIAP_003310"
     CDS             complement(7524..8069)
                     /locus_tag="ACOIAP_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HGZ2640185.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(8187..10010)
                     /locus_tag="ACOIAP_003311"
     CDS             complement(8187..10010)
                     /locus_tag="ACOIAP_003311"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640186.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKSLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPTVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYEIKSVNDFKEINDRLLKISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGVLASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEKEEQELDNMFKSELKDNKDGNSNSHFVKGEIELKNVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDSKDIYSIDRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANSHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(10023..11798)
                     /locus_tag="ACOIAP_003312"
     CDS             complement(10023..11798)
                     /locus_tag="ACOIAP_003312"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640187.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGVIMIGITFLGAIFAIIRSVISARVSQHFSYYLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKVGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENKSF
                     EELNYELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRYLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLIDEDEEVIERDKSSDIGEKDLKFA
                     NCDIIFENVDFAYNKNTGEKILKNISFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGHSIYSISEESLRERIGVVFQNSSVFGKSILENVVMGNRNIRKEDVIKSC
                     EIANANQFITKLENSYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKDHISNLRENEGKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFTLQNLVSEDVN"
BASE COUNT         3989 a         2153 c         1089 g         4717 t
ORIGIN      
        1 actaaagtca caagtgtgtg tagctatttt ttaatcaaat ttaaacataa tatttactca
       61 tattgcttaa tttagcaata atccctccta atcatatatt tatttataat tatacagtaa
      121 aattacaaca tagtctaact tacttcaaat atgaaatttg ttatttatat aaaaaataag
      181 aacctgataa taaagtaatc taaacttttt atcaggctct tatcctattt atctcttagc
      241 actatggcaa ctcttactac ttgagcatcc agaacaacca catccacaac tgctaccatt
      301 cttttttaaa tttttaatca tatacattac agccaatgcc attaatacta ctacaatagc
      361 tgctattata aatgtagcca tatttatcac tccttattta tatgaattaa tttttcatat
      421 aacttaattt acccattttt tcttttttca tatttctatt tgaataagtt aaaactgcaa
      481 ataccactcc tactgctata actacagata ttattgcccc agcaatactt cctccagtac
      541 ctaaaactaa acttccaact tgattgataa gaagagcaac tatatatgct gttaaagtct
      601 gaaatcctaa tgtaatccat gtccacttcc atgaacccat ttctcttttt atagacccaa
      661 tagctgcaaa acaaggtgca caaagcatat taaacgccat aaatgcaaac gcattagcta
      721 ctgtaaacat acttgcaact gaagcaagaa gtgttgggtc ttgctctgtt gcatctgata
      781 ttccaaataa aacaccaaat gttccaacta cattttcttt agctactaga cctgtaactg
      841 ttgctactga tgattgccaa tttccaaatc caagaggcgc aaatattggt gcaactatat
      901 ttcctaagct agctaatata ctatctccag catctaccat ttgtaatgac caattaaatg
      961 attgtaagaa ccaaatcact ccacaagcaa caaatataat tgttcctgct ttgactataa
     1021 atgcttttcc tctatcccac atatgtatta aaacaccttt tatacttgga atatgatatt
     1081 gaggtaattc cataacaaat ggagatggtt ctcctgcaaa taaactagtt ttctttaata
     1141 taattccaca aatgattatc attgcaatac ctaagaaata cattgatgga gctacccatg
     1201 aagcacctcc aaataatgcc cctgcaaata atgctattat tggaacctta gctccacatg
     1261 gaatgaatgt agttaacata atagtcattt ttctatctct atcattctct atagtacgag
     1321 ttgacataac tcctggaact ccacaacctg aacttataag cattggtata aatgattttc
     1381 ctgaaagacc aaacttacgg aaaattctat ccattataaa agctacacgt gacatatacc
     1441 cacaatcttc taatattgat aataataaga ataaaagcat gatttgtggt acaaatccta
     1501 atactgctcc aactccacca attaaaccat caactacaag tccttgcaac cactctgcta
     1561 catttaaaga agctagaaaa ttacttacat taccttgaat aatttctcca aacagtacat
     1621 catttgtcca atcagttgct atagtaccca atgaacttac tgctatatag taaactcccc
     1681 acattataag tgcaaaaata ggtaatgcta gtatacgatt tgttacaatc ttatctatct
     1741 tatctgatac agtttcctta ccttttctat tcttctttat tatatttgaa attattgaac
     1801 taataaactc ataacgattg gctgttatta tactttcact atcatcatcc aattcatctt
     1861 cacaatttct agttatttct tcaatgctat tcaatattgt tttagaaata tcaagttttt
     1921 gtataacatt ttcatctctt tcaaataact ttatagctaa ccagcgtgtt tctacatcta
     1981 tatatggagt cttttcttct attatttttt caattttttc tattgcttcc ttactttcat
     2041 caacgaaagg taatttgaaa tttaatttat tgttactact tgcaagttca actgcctttt
     2101 cagcagcctc cataattcct tgacctttaa ctgctgttac ttctaccact gggcaaccta
     2161 taacttcaga tagttcttta atatttatct tatcaccatt cttattaaca atatccatca
     2221 tattaagagc tataacggtc ggtataccca gctctaaaac ttgagttgta agatataaat
     2281 ttctctctat atttgatgcg tctacaatat ttattactgc atccggctta tcatctaaca
     2341 taaaattacg tgtaactact tcttctaatg tatatggaga taaagaataa atacctggta
     2401 aatctactat ctccacatct ttatttcctt ttaactttcc accttttttt tcaactgtta
     2461 ctcctggcca gttcccaaca tattgtgatg aacctgtaag accattgaac attgttgttt
     2521 taccacagtt aggatttcct atgagaccta tttttattga catttccatt ccctccatta
     2581 ttatttaagt acataactat tcatgataca gaaaatcatt ctcattatat aatcgcacta
     2641 aacctattct aactaattaa ttttattatt ccacaataat cttttctgca tctgatttac
     2701 gaattgatag ttcataatct ctgactgtta tctcaattgg gtcaccaaga ggagctactt
     2761 ttcttataaa tatattaaca cctcttgtaa tccccatatc cattatacgt cttcgtgtag
     2821 ctccttcgcc ttctaacttt ttgactttta cagtctctcc acacttaata tcctttagcc
     2881 tgttcatatt attacctccc tatattatta ttctacttgc cattttttta tctaatgcaa
     2941 ctctagtatc ttttacatct attattaagt taccatctat cttagaaact atcttaacat
     3001 ttgtacctac tacaaaacct atactattta aaaaagtcct cgtcttatca cttcctgaaa
     3061 ttttctttat aactacttct tcacctgtat ttgataatat caatggcatc atatagtaac
     3121 cctcctctta aactgattta aatccacaag caatcatcat ctaatatata aattacaata
     3181 tcttaaatct taatctatta aaataatcct ctattttttt ccttcttttt acaactccta
     3241 attttgattt aagtctacca caatagtatg ttttttgcaa gtgattattg tattcttttg
     3301 attttttttc tcatttgatt cattatatta ataaaacagt aaaaattaat acaaaaataa
     3361 agatgctcta aaatagtata ctcaactata ttaaagcacc tttattatat atgtcattac
     3421 ttaaacattg ctttattctt ttttaaaggc aattttttca aactctttta caggcattgg
     3481 cttagaaaac aaatatcctt gtaccatatc acaaccaatt tgctttagaa attctacttg
     3541 cgaaatagtc tctactccct ctgatattac tttcattttc agttcctttg ccattttaat
     3601 gacattagat ataacaattt tttcattatt actctcatct ttttctgtaa aaaatgctct
     3661 atctagtttt aatatatcaa caggcaactc ttttaaaaga ttaagagagg aatatcctgt
     3721 accaaaatcg tccatagaaa ttacaaatcc attttctttc aaattgttca ttgtatcaag
     3781 taaaccttct atattatcta atactgctgt ttctgttagt tctaattcta taaggcttgt
     3841 cggaattttg tatttatcta caattaactt aaacttctct ataaaattac tatttacaaa
     3901 atgcattcgg gacaagttta cagatatagg tactacttct tgaccttcat ccatccattc
     3961 tctaatcttt ttacacactt cctcaaatac atagaaatca atatttacaa taaaaccatt
     4021 tctctcaaat acaggaataa attctatagg tggtattaga cctttttgtg gattatccca
     4081 tctaacaaga gcctctgctc ctataatctg ataatctgaa agcctatatt taggttgaaa
     4141 ataaacaaca aattctccat tattaagagc atctaccatt gagttttcaa tttctttctc
     4201 ttttaatatt tttttatgca tttccttatc gtaaaaagca aatgaatttt tatgaccacc
     4261 ttttatagtt tttcttgcag tattagccct atccatgata gtgtttatat cattatcact
     4321 tttacttatt ttatatatac cacaatctaa aattaattta taatagttta ttttaggatt
     4381 actaaatatt tgaaccttat tataaatact gtttaacctt gttttaatat catcatctgt
     4441 cttatactta ataagaagaa caaaatggtc agcagaaact cttgcaaaaa tttcatcttc
     4501 ctttaattca cttgcaatag tatctgatat atgtatcaaa gtattatttc ccatatcata
     4561 tccaaacata tcatttatat atttaaattt gtcaacatcc atataaaaca acgcatattc
     4621 ttctggatta ttcttagcaa acagtttatt cgaatttatt ttaaatttat ctatactgtc
     4681 tgctcctgtc aatgaatctg tatatgctat cctctttaga tagtcctctt tcttcttttt
     4741 attataaatt atatatttaa tagcaattaa gaataaaata catacaaaag aaataatttg
     4801 tattgaatat tctttaaaaa tcacaccaaa tggtacttta taaggtttgt caatagtatt
     4861 agaatatatg caatcactta attcttcttc agtaatttta tctattgact tatttaaaat
     4921 agacactaat ataggattag ttttatttga tacccctata cgcatcccat aacttgtgtc
     4981 taaaacagat ataacagata aattctcact ctttcctttt cttaaaagtt catcaaactg
     5041 ataagaacta agtaccatta aattagcttt accttcattt atagcgttta aacaactttc
     5101 tacactatta taagatgttg tcttagcatt ttcaaaactc ttttctatat aagaatcaat
     5161 agacttatag ctactagtta aagcaatatt taaatcatta ttgagattgg tatccaattt
     5221 tcctaccata atcattggaa tatttatgta tggatttgtc aatttcatat taaatcgctt
     5281 tgccttatca ttttcattga ttgaaccaca tatcatagtt gcctttccac tttttatgta
     5341 atcaaggctc tcgttataat tttttgtttt aatatattca aattttatgc cacatttttt
     5401 tgatataatt gacattaaat ctgaacttat gcctttaaat gaattacttt tcttatcata
     5461 atactctaca ggagaccact ctgaatcata caccatagta agttttggat ttgctttaat
     5521 aaaatttatt tcttgtcgag taaatgctat ggaattgtta acctctcttt tgaaatattt
     5581 tttatataat tccagctcat aatacatatc atttattttt aattctttta aagcataatc
     5641 taattctttt gccaaattag gtttatcttt tgcagtagca aaataaaaag gttctactga
     5701 aaatttacta actattttca ttcctttagc atctataata cttccacaaa caaatgcatc
     5761 tgcttttttt tcattgacag actcaatcaa ttcatcaata gaattacagt atatatattc
     5821 aactgaaaaa ttattttctt ctctatactt ctcaaatgca atattatgaa agtttcctct
     5881 aagtacagcc actctcattc cattaaagga atttatatct tcataaaaca tattattgtt
     5941 actatcatct gtatataatg cactatattc atatcctgaa cttagtttag gaaaattaaa
     6001 tattttattt ctttcatcat ccttctgtaa aggtccaagt aaatctattt cacctttttc
     6061 taatctatct aaacattctt cccaagaccc ctttataaat tcatactccc atcttgtata
     6121 ttttgagatt tctcttagat aatcataacc atatcccgaa taagaatgct cttttgatga
     6181 ggatattatt ccatagtcat cacagtatcc aacttttatt ttttttgaat tttcagactc
     6241 atcagcaaag catagtatat tattaaaaca tgatataata agtaaaaata tcaaagaaag
     6301 tatcaagaag tgctttttaa atgctttcat atttaaaaac ctccaatttg ccaacttact
     6361 ttaacttatt tggttttcta gttgtaacta cttttattgt aatggtaaat atatcaaatt
     6421 gcaatattct catataatat tcttatttaa ctataatgaa tttatcatta tctatttaaa
     6481 taccatgtct aataccaatt tcttataaat cataaaagta taattaacac cataattcta
     6541 gtgattaatt ttatttcaaa aaatgtaata acactaccaa tattttaaat atcaatagtg
     6601 tcaaaaattt tttcagatta attaaatctt tatatatatt ttataataat ccaaatcata
     6661 ctaaacattt agacagaaaa cttttttctt taacagtaaa tgcttttgtt tgaatatcag
     6721 aataattctt tgaatatata tctataaaac catgatttgc atctaaaatc tcaatttgga
     6781 tattttgttt tctagaaagt tggcaagaaa tagaattaac atcaaatgaa tcgtactttg
     6841 caaatactaa caaagtagga cattttggaa ttacatccat gtaatctctg atacgagaac
     6901 cataacaaca gattatgcca tcacaaagag aatcttcact acatctccat gcaatagttg
     6961 ctcccacgct atacccagca ataaatacat atttatactc tgattttaaa tcatttataa
     7021 gcttttcaac ttttttataa atatcaaaac caacattatt tataaaaaaa tcatatgcct
     7081 cttgaacttt tgaatatgga aaaactcttt tttctcccag aagttcagga caaaatacat
     7141 catatccata tttataatac ttttgacaaa catcttctat aaagctatta atcccataga
     7201 tttcatgcaa aacaacaata gctacatcac ttttatgtat atactttatc agattatcca
     7261 ccacctttac aaaatagcaa attttttata cttagtttaa tatattattc tttacatgtc
     7321 aattcacttt tttaaaacca aatttatttt tggattaatc acttgttttt aaaaattgtg
     7381 tattattact cttaaattat tccctattgt taaaaacata attgttagaa ataaaaaata
     7441 tagtataaat aataaaaaaa tatctcactc ataactttaa aaattataag tgagatactc
     7501 ttaaaatcta ctttatatta aatttatttt ccaaaatatc tatttaataa tcctaagaat
     7561 gctttaccat gtctagcttc gtctttacac atttcatgta ctgtatcatg tatagcatct
     7621 aatcctaact ctttagcttt cttagctaat tttaattttc catcagttgc accatattca
     7681 gcatcaactc taactcttaa gttttctttt gtatctgcaa ctacaacttc tccaagaagt
     7741 tctgcaaatt tagcagcatg ctcagcttct tcaagagcta ttctcttata agcttctcct
     7801 acttctggat aaccttctct atcagcttgt ctactcattg ctaaatacat tcccacttct
     7861 gtacactcac caacaaagtt agctcttaat ccttcgatta tttcttcatc tacaccttga
     7921 gctactccta ttctgtgctc atcagcccaa tttttttcgc ctttcatttc ttcaaattta
     7981 tcagctccaa ctttacatac tggacattgt gctggtgcag catctccttc atgtatatat
     8041 ccacatactg tacaaacaaa tttcttcata attaatttcc tcctaaattt tatatatcaa
     8101 attaaatttt ttatttatta agttagtcta tatatacccg caccatatac ctttaaacaa
     8161 ttttttttaa agttttttct aagtacttat tttccctgtg tcaatagtat gtttctataa
     8221 taatgtcctt ttaattttat caattcttta tgatttccag attctacaat tctaccattt
     8281 tctaaaacta ttatattatc acaatttgat atagtactta atctatgagc tataattata
     8341 cttgtttttc cataagttaa attatttatt gcctcttgaa ttttagcttc tgttgctata
     8401 tctatgttgc ttgtagcttc atccaaaata agtattggag cattttttaa taccgctcta
     8461 gcaatactta ttaattgttt ttggccttca cttaaatctt cacccctatc tgataataca
     8521 gtactatatc cttcacgcat tttaactata aatttatgtg aatttgctat tttactagca
     8581 tatataactt cttcatcagt agcctccaga tttccatacc ttatattttc cataactgta
     8641 tcattgaata tataaccttc ttgtgggact acaccaaaac acgttctcaa atagtttctg
     8701 tcaatagaat aaatatcctt actatctaaa aatatacttc cttcatctat atgataaaaa
     8761 tttgtaatta gatttataat tgttgttttt ccacttcctg tctctcctat aatggcattt
     8821 gatgtaccag ctttaatttt taggtttata ttatctaaaa ttttcttttt tgaatcataa
     8881 gaaaaactta catttttaag ttcaatttct ccctttacaa aatgagagtt tgaattacca
     8941 tctttattat ccttaagttc acttttaaac atattatcca attcttgttc ttctttttca
     9001 tctataattt caaaaactct ttcacatcca gctatggctg aaagtaatgt attaaataga
     9061 tttgccaatt catttaaagg tcttgtaaat tgtcttacat aacttaaaaa actagctata
     9121 acccctatgg ttataatatc tttagatgca agaacacctc ctataataca tatagttgca
     9181 aatcctatat tactaatcac attcataata ggcattaaaa gagaagtata aatttgagat
     9241 ttaagggaaa tctttagaag tctatcattg atttctttaa aatcgtttac agattttatt
     9301 tcataattaa aagattttac tacatttatg tttgatatca tttcttcaat atgagcattt
     9361 agttttccca actcaacttg ttgttgttta aaaaaaactc tagttctctt tgcaataaaa
     9421 ttactcacaa acattactgt cggtattaat attacactgc aaaaagttaa aattggactt
     9481 aatacaaaca tcataataaa agtcatcaat atgtttaaga ttcctgtaat taattgtact
     9541 agtgaatttg atattcctgt actgatatta tcaacatcat ttgttactct gctcataata
     9601 tctccagtag aactcttatc aaaaaaggtt attggtagac ttttaaattt taaaaataaa
     9661 ttactcctca tctctttaac tatactttgg gataatctag ctgtacatat ccccttagac
     9721 agtttaactg aaaactcaat tatataaaat gaaagtaaaa taattattcc ttttaagaaa
     9781 atggattttg aataagtatc aatatctatt atgtcaacta cctttccaat agtgtatggg
     9841 attacagttg atataattga atcaattatt actagcaaaa aaataaatct agtaatcttc
     9901 ttatctttct taaagtacat aaaaattctt ttaaaagttt ttttaaaatc tttaggcttt
     9961 tcttttttct ttaatctact gaccttttga tttccagtac ttaaattcaa tatacttcct
    10021 ccttaattta catcttcact tactaaattc tgcaacgtaa aaattttttt ataaattgga
    10081 gaactaacca gtaaatcttc atgtgtagca aatccaacca cctctccctc atccaagact
    10141 aaaatcttat cacagtcaat tatagaacta atcttttgtg aaatagttat tactgtacat
    10201 ttcttacctt cattttctct taaattgctt atatgatctt ttatattctt tcttataatt
    10261 gtctctgtat taatatccat tgcactaaaa caatcatcaa gaattaatat ttgtggtttt
    10321 tttgctatgg ctctagctat agtaattctt tgtctttgcc ctcctgatag atttttaccc
    10381 ctttgaaata aaacttcatc ataagaattt tcgagttttg ttataaattg atttgcattt
    10441 gctatttcac atgattttat aacatcctct ttgcgtatat ttctatttcc cataactaca
    10501 ttctccaata tactttttcc aaacacacta ctattttgaa atactacacc tattctttct
    10561 cttaaacttt cttcagaaat actgtatata ctatgtcctc caatcttaat atcgccttta
    10621 tcaattatat ataatttttg aattaaattt actaaagaag tctttcctga accagtttga
    10681 ccaatcacac caatattttg accttcttct attttaaaag atatgttttt taatattttt
    10741 tcacctgtat ttttgttata cgcaaaatcc acattttcaa aaattatatc acaatttgca
    10801 aactttaaat ctttttctcc aatatctgaa cttttatctc tctcaattac ttcttcatcc
    10861 tcatcaatca aaacctcact tattctctca taagacgctt ttgctctaac aaaaacatta
    10921 aaaacatgtg aaatcattat aagagatgtt aatattctag tcatatagtt tacataagca
    10981 actataatcc caattttaat ttctcctgaa taaattaaat atcttccaat cagtaatatt
    11041 attattattg aaacattaat gattattgta attgtaggtc taaaaaatga catcatagtt
    11101 gtagcttttc tactattttt aaaaagctca taatttaact cttcaaaact tttgttctca
    11161 taatcgtatc tgcaaaatag tttaactact tttattccac ttaaaaactg tcttaatttt
    11221 gaatttactt tatctgtact ttcttgtaca tttttaaata atctataccc taccttcata
    11281 ttaagcaata ttataataaa tataattaaa actgcaatta gaataattat tgacatcttt
    11341 aagtttaatt ttatggctat aattaaactt cctatgcaca ttattggtga ctttataaaa
    11401 actctcatca tcccattaac gaattgttgc atttgattaa tatcattagt aattctcgtt
    11461 attaacgaag ctctaccaaa tttatctatt tgttttaacg agtatgtatt tatcttttca
    11521 aatacatcct gtcttaaata ataagaaaaa tgctgagaaa ctcttgccga gattacactt
    11581 cttattattg caaatattgc acctaaaaaa gttataccta tcattataac tcctgttgat
    11641 agaatgtaat ctaagttctt atttgaaact cctatatcta ttatttttgc cattatagtt
    11701 ggttgagcta aatcacaaaa agcttccagt gtcaaaaaaa atactgctgt tagaaataat
    11761 actatatatt tttttatgta ttttttaaaa tacctcattc aatcatccct tcatagaatt
    11821 ttctcattac caaaagtata tcataatggc taatttaatt gattatatca attataaata
    11881 tttgatttat tattaatttt tataccatat attttataaa ttatttgttt ttatttccta
    11941 tatttata
//
LOCUS       DBGJFK010000100        11185 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.105, whole genome shotgun sequence.
ACCESSION   DBGJFK010000100 DBGJFK010000000
VERSION     DBGJFK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11185
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.105"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            561..1268
                     /locus_tag="ACOIAP_003313"
     CDS             561..1268
                     /locus_tag="ACOIAP_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGZ2640188.1"
                     /translation="MIFTKSNKYDKEFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLANEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISVDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSIKWWNELWSDSESVTVEKCEALNCHDEAWQDWLNCDNSYARNDKKMME
                     VENGKYFNTISLVARVK"
     gene            1848..2348
                     /locus_tag="ACOIAP_003314"
     CDS             1848..2348
                     /locus_tag="ACOIAP_003314"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2640189.1"
                     /translation="MIEGIKFIKAEKKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTITKNLPQLFVIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIINLSKEYGYEKIELDVLKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(2589..3368)
                     /locus_tag="ACOIAP_003315"
     CDS             complement(2589..3368)
                     /locus_tag="ACOIAP_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640190.1"
                     /translation="MNKNILNNSFPEVPESFHNSLNKTLNSLPEREENYKMINNKTHK
                     LPFGKGLVATLAITLILGTTALAVGQISSLVAKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNEEALDKEDNVLGELKALSFEYKNGNDEISLKTANNVLGNS
                     SDNLKVVDTYKDINISYKAFAQKFVPEGYKMTEQDKVDEKSGKYTFSVGPNNESGKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNELVKMVHEVIDAK"
     gene            complement(3365..3844)
                     /locus_tag="ACOIAP_003316"
     CDS             complement(3365..3844)
                     /locus_tag="ACOIAP_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGZ2640191.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKFLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            complement(4373..5776)
                     /locus_tag="ACOIAP_003317"
     CDS             complement(4373..5776)
                     /locus_tag="ACOIAP_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2640192.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEVCYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     misc_feature    6481..6623
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            6645..7154
                     /gene="infC"
                     /locus_tag="ACOIAP_003318"
     CDS             6645..7154
                     /gene="infC"
                     /locus_tag="ACOIAP_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGZ2640193.1"
                     /translation="MSKELAINEQIKDKEIRVLSQTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            7182..7376
                     /gene="rpmI"
                     /locus_tag="ACOIAP_003319"
     CDS             7182..7376
                     /gene="rpmI"
                     /locus_tag="ACOIAP_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGZ2640194.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAYKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            7432..7788
                     /gene="rplT"
                     /locus_tag="ACOIAP_003320"
     CDS             7432..7788
                     /gene="rplT"
                     /locus_tag="ACOIAP_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGZ2640195.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            8089..8634
                     /locus_tag="ACOIAP_003321"
     CDS             8089..8634
                     /locus_tag="ACOIAP_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640196.1"
                     /translation="MNDKLMDCFVNPIKCKLLLEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSVFSVCPVYASIDEIVEASKKIASILEPLKNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            8819..9736
                     /locus_tag="ACOIAP_003322"
     CDS             8819..9736
                     /locus_tag="ACOIAP_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HGZ2640197.1"
                     /translation="MRLITRSDFDGLVCGALLKEAGIIDSWKFAHPKDLQDGLVEVTE
                     DDCLANVPFVEGCGLWFDHHSSEFERNKLEGRYKGESRIAPSCARIIYEYYGGNERFS
                     HFNEMLEAVDKVDSGNLTIEEVQNPSGWILIGYLMDPRTGLGRWRNFTISNYQLMEKL
                     IDACRTLSTKEILELPDVKERIEVYFEQTNKFKEMIAKYTRVEGDVIISDLRGVEPIY
                     TGNRFMIYSMYPEQNISAWIVNGKGGKGCSVAVGYSILNRTSSVDVGSLMLKYGGGGH
                     KAVGTCQFNDEQIDELLPKLLDELVNTKN"
     gene            10124..11155
                     /locus_tag="ACOIAP_003323"
     CDS             10124..11155
                     /locus_tag="ACOIAP_003323"
                     /inference="COORDINATES: protein motif:HMM:NF012376.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGZ2640198.1"
                     /translation="MKIKFVIMTLVIFLIALLVGCQSTKDTEVKVKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLIMVDAGDFYGTQSREMWEWSSGKKLINIRRDSRAEY
                     DDIIKNSKDEVPIVKEMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARALGEQ
                     ADYKGKLYANDLIEDAKKWIKVMKKESPDIIVAVVHSGEEHKMDRNPGNRIKELATTV
                     DGIDVIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENDKWVIKE
                     KSSKLKMID"
BASE COUNT         4285 a         1250 c         1832 g         3818 t
ORIGIN      
        1 taagttaatt agtatatagg ttaaagtgga agtaattaaa acttatcaag tatcagaaaa
       61 cgacttctta ttagagtaag tatctaaaat gatataaaaa ttatgattac ttattaaagt
      121 gactattata gagtagataa aattacccat taaaataact ataatagagt ggataagatt
      181 actcattaag gtgattattg tagagtagat aaaattaccc attaaaataa ctataataga
      241 gtggataaaa ttactcatta aggtgattat tgtagagtag ataaaattac ccattaaaat
      301 aactataata gagtggataa aattactcat taaagtaatt attgtagagt ggataaaatt
      361 acccattaaa ataactataa tagagtggat aaaattactc attaaagtga ttattgtaga
      421 gtggataaaa ttactcatta aaattacctg ttaaagaatg aataaaaaag agattgctca
      481 ttataagaag catataaaaa ataaaaaatc aaacgtataa aatttaataa ataataattg
      541 atagggaaag gaaagataga atgatattta caaaaagtaa taaatacgat aaggaatttc
      601 ttatgaaaaa tatgatggga cctaattgta taaagatatt ggaagaatta acaagtaaga
      661 taaaactaga aaaggggatg cgtattttag atttaggatg tgggaaaggt atatcctcga
      721 tatttctagc aaatgaattt gatgctactg tatttgcaac agatttatgg atagaaccaa
      781 ctgaaaacta taaaagattt aaagagttta aattggatga caaaatattt ccaatacagg
      841 cagaggcaca tgaattacct tatgcagaag gtttctttga tgcagtgata agtgtagatt
      901 cttatcacta ttttggaaac aaagaaggtt ttttggataa tcatatatca cctcttgtaa
      961 aagagggggg aatacttgct atggcaatgc ctggattaaa agaagacttt gtggattgta
     1021 taccagatga actcattcca ttttggcaag acaacatgaa cttccattca attaaatggt
     1081 ggaatgagct ttggtctgac tctgagtctg tgacggtaga gaaatgtgaa gctttaaatt
     1141 gtcatgatga agcttggcag gattggctaa actgcgataa ttcgtacgct agaaatgaca
     1201 aaaaaatgat ggaagtagag aatggaaagt attttaatac aatttccttg gtagcaagag
     1261 ttaaataaaa gtataagata agtgagagta ttaaacgaat agaaatataa gttgaatgaa
     1321 agcagaagtt aaataaaaac gtaagttaaa agaagagttt atataaaaaa tgatttttta
     1381 tattatttat gcccaatcga attttttagt gcaattgggc atttttattt tttctaaggt
     1441 tagatgtcaa atactattgc gctatatata ttttaatact aaatgtttat tttatgagaa
     1501 aaaattaata aaaaagcagt tataacaata aaaggcaaaa aagatattga tgaagattaa
     1561 agattttata gtaccatttt agatgttttt ttatatattt tattatactt taaattaaat
     1621 ttcaaaatga ttaagtatat atactcaaaa tattaaagaa ctatatttat tatactatta
     1681 aaaattattt taatagagat acaaaagata gatatattgg ttttaatttt atagaaatat
     1741 acaaagatat tttaagctaa tatatagtaa tttatatagc attataaatt agaatcatat
     1801 aaaataagtt aactacaatc ataaattaaa aaaggggaaa tgttaagttg atagaaggca
     1861 taaaatttat aaaagcagaa aaaaagtata tttattcgta ttggcaaact tttgataaaa
     1921 tagcaaaaga gaggaaatat ctagctatgg atgaggcctt tccttttgaa gaaacagttg
     1981 aatttataaa aaatactata actaaaaact taccacaact gtttgtaatt gatttagaat
     2041 cagataactg tattggttgg tgcgacgttt tacctaaaac tgaaaaagtt ggttatttag
     2101 gcatgggtat tcttaaagag tatagggaaa aaggcattgg aagtagtctt ttaaaacaaa
     2161 ttattaattt atcaaaagaa tatggatatg aaaaaattga gcttgatgtg ttgaaaagta
     2221 atagtagagc tattcatgtt tataaatcct tagggtttgt agaggtaaat acaatatcta
     2281 gtggttttac atggaatgat agacctgtaa aagaagaggt aattcaaatg gagcttacac
     2341 ttatataaaa taaagttaaa ccccttaaaa ttccatatac acttatataa aataaaatta
     2401 aagcccttaa agttccatat aaatttaagg gctttttaat agtgcttctt ttgaaagtag
     2461 ttaaatatct aaaattttat atattaaatt taaagaaaat ataaagatgg aagatacaac
     2521 catgtttgct aataaaaaaa ttaaagtcgt aaataataaa ctcataaaca acttattatt
     2581 acttatgttt attttgcatc tattacttca tgaaccattt taactaattc attcatagat
     2641 aaatttgagt cttgaactgt aaaagaatag taaactccat cttgtttcca tgtcaaaaac
     2701 ttaaattcat taacttcaac tttacctgat tcattatttg gacctacact aaatgtgtat
     2761 ttacctgatt tttcatcaac tttatcctgt tctgtcattt tataaccttc tggtacaaac
     2821 ttttgtgcaa atgctttata agaaatatta atatctttgt aagtatctac aacttttaga
     2881 ttgtcagaac tatttccaag tacattattt gctgttttaa gtgatatttc atcattacca
     2941 tttttatact caaaactaag tgcttttaat tctcctaaaa cattatcttc tttgtcaagt
     3001 gcttcttcat ttacagtata tgcaccttta aatttatatc cattactaaa ttcagaaact
     3061 atattagggg taaagttaaa gtcttttttt acttgttctg tagttgggat agatgtatag
     3121 gtagctttag tacttgattt tgcaactaga ctagatatct gccctactgc aagagctgtt
     3181 gtgcccaata ttaaagtaat ggccaaagtt gcaactaagc cttttccaaa tggtaattta
     3241 tgtgttttat tattaatcat tttataattt tcctcccttt ctggtaaact atttagtgtt
     3301 ttatttaaac tattatgaaa actttctgga acttctggaa acgaattatt taatatattt
     3361 ttattcatat gattacctcc gtgttttcta atttagtttt taataatctt cttcctcttg
     3421 ataatctact ttttacagtt ccttgaggta tatctaatat ttccttaact tcatctactg
     3481 aataaccttc aatatagtaa aggactattg gaattttaat ttttttaggt agactttgaa
     3541 tagcagtata caaatcacta taatcatctt tttcatcaat ttttttgttt ttgaagacgt
     3601 cttcaaatga tagaaatttt aatcgtttac gtcttaatga attacattca tttatgacta
     3661 ttctaatcaa ccaggtttta aagtattgtt cttctttaag agaatccaac ttttcatatg
     3721 cttttaaaat agcattgttg acggcatctt cacagtcttg gtcgtttcct agaatagact
     3781 tagatactcg atacaaagtc tgttctgatt caagtatatt gtttgtaaat gtagttttat
     3841 ccaattgagt tcctaccttt ctatgcaaat cgtagcgcta cttttttgcc tttcacttat
     3901 tagataaaat tttactatag atggttcact ttctttataa ttatttgata aatttaagtt
     3961 taaaagtttt gtctattcta tacaaatatt ctataatata tttttttaca gtcatatata
     4021 aagccatgta tatatgaaac tttagaagct atttatatat ttagttttat agtaagtgtt
     4081 tatattgagt aattagaaaa taataagtat ttatgttgag tagttggaaa ataaataata
     4141 tttttgaatt atttaattca tgtatagatt taaaataagt tctttaaata gcgactttaa
     4201 atagatataa gtcataaatt aaatagacaa aattaaaaga tggaagtata tcaaaatgaa
     4261 ttttttagtt cataaggcgt tttttgtatg aaatcaaata agtttttata attttaacaa
     4321 taaaaagagg cttatctcta ttttgagata gcctcatatt tttaaaacta tactagttta
     4381 cagcttcctt tcctatcaaa tcttttaact cttcatgagt catagtttct ttttcaaata
     4441 agaatttaga aacagaatgt aaatcttcaa gattatcctt taacatctct aaagtctctt
     4501 tataacaaac ttcaactata cgatttgctt ccttttgaac tttatcacat aagaaagtct
     4561 tatcatttcc atcaatagtc ataaacccta aattactcat accgtattca caaaccattt
     4621 gattagctat ttcagtgact ttctttaagt cgtcctttgc accagtagat ttatgattaa
     4681 atattaattc ttctgaagcc tttccagcaa gtaatatttt tatttttcca atcaattcat
     4741 ccttagtata aatatatcta tcttcatcag gtaattgaag aacataacct aatgcttgtc
     4801 ctctaggaac tatagatatt ttttgtatag gacaaattcc tactatatca cttacaagag
     4861 catgtccagc ttcatgatac gctactattt ttttctcttt ttcaaccaat gcagagtttt
     4921 tagattctag ccctgcaata actctttcaa gtgccttgtc aaaatgttct gatgtaatac
     4981 actcactgtc atctctaact gcaaatatag ctgcttcatt tgctatattt gaaagatgag
     5041 ccccattaaa accatgagtt tttttagcta aaagttctag atttacagat ttgtctatag
     5101 gtttgtcatc tgtatgtacc tttagaattt caaatctagt gtgataattt ggtgcaccta
     5161 tatgaatgtg tctgtcaaat cttcctggtc taagtaaagc ttcatctaat aagtcaagtc
     5221 tattggtagc acctattatt aatacattgg aatctttatt aaatccatcc atttcaacta
     5281 aaagttggtt tagtgtttgg tctttttcgt tgttactttc aagatgtctt tttgctccca
     5341 cagcatctat ttcatctata aatattatac ttggagcttc ttttctagct ttttcaaata
     5401 gagttctaac tctttttgct cctacaccta catatttttc aacgaactct gaaccagtaa
     5461 cattgaaaaa tgatgagttt gtttcaccgg ctacagcaga tgcaagtaga gttttacctg
     5521 ttcctggagg accataaaat aatactcctt taggtatttt tgcacccatt ttttgatatt
     5581 tttgtggtga tttcataaaa tcgactattt caaatagttc ttcttttact tcgtctaatc
     5641 cagcaacgtc tctaaatgta gtctttggtt ttgtagaaag tgaatcatct gtttgattgt
     5701 ctctttccat ttttgtttgt gcaaagacag gagctggatt gttaattttc ttaaaaaagt
     5761 tgtttagcat tttcatattc acacctcagg taattaatta ttgttaatca attttatatt
     5821 ttccatattt actatttttt attatttatt tttcatggaa aaaatataca tgttatctaa
     5881 ataaaaataa acttgtaaga tgtatgaaaa agtgaattta tgtatataga gatttctatt
     5941 tgtgtattga ataaagtaat acaaattata aattatgtat tgattatatg ttgagtaaag
     6001 tattataaag catgtattga ttaagtattg aataaaatat tacaaattta gatgaaatga
     6061 aaatgataaa aaatgttgta ctatacttta caaatcatat aaatggaaaa attgttatag
     6121 cacaaaatag tgagtagcat attagaatat aatatagaat ttgttgtgca gtatagtagt
     6181 atattagaat ataatgtaga atttgttgtg tagtatagta gtatattaga atataatata
     6241 gaatttgttg tgtagtatag tggtatatta gaagacaata taggatttgt tatgtagaat
     6301 atatggagtc atttagaata tacatattat aaaaggattt tgggtataaa tttaaaaatt
     6361 aatagcaaaa tgagtagtat agacatataa ttagtagtag gaagtaatta aatttttcct
     6421 aaaccaaaaa aaacagttgc aaataatttg attaagtgat atagtaaata aggtaagaat
     6481 aaaacaaaga agaagtccgc ttctcacctt acgccagagg ttagtaaggt aaatataagt
     6541 taaagcttaa tttcaattta agcttgttta aatttggtaa cttatattgc ggatgattac
     6601 gtcatccgct ttttatttta taaaaatttt ggaggtgtcc tacaattagc aaagaattag
     6661 caatcaatga acaaataaaa gataaggaaa taagagtcct ttcacaaaca ggtgaacaac
     6721 ttggagtaat gcctactaaa gaagctcaag caatggctaa tagcaaaaac ttagatttgg
     6781 ttcaaatctc gccaaatgca aatccaccag tatgtaagat aatggattat ggaaagttta
     6841 gatatgagca agcgagaaaa gagaaagaag ctaagaaaaa acaaaaaact atagttgtaa
     6901 aggaagtaag acttagacca ggtattgaac aaaatgattt aaatacgaaa gctaataatg
     6961 ctataaagtt ccttaaaaaa ggggataaag tcaaagttga acttagattt agaggaagag
     7021 aattaggaca taaagacata ggtaaagaag ttatgcttaa gtttttagat ataataaaag
     7081 agtttggaga accaacaaaa gcccctgcat ttgagggtaa taatatggtt gtaattatag
     7141 atccaaaaaa atagatgatt aactgagagg aggaatttgt catgcctaaa atgaaaactc
     7201 atagaggtgc agcaaagaga ttaaagaaaa caggaactgg aaagttaaag agagctaaag
     7261 cttataaaaa acatatatta actaaaaaat ctgcaaaaac taaaatgaac ttaagaaaat
     7321 caactttagt aagtgatgga gatgctaaga gaatagcaca attattacca tactaggata
     7381 cagattataa ataataacta tagaagaggg atataaaagg aggtcataac gatggcaaga
     7441 gttaaaaaag ctatgaacgc tcgtaaaaag cataagaaaa tattaaaact tgcaaaagga
     7501 ttcagaggat ctagaagcaa attatataga ccagcaaata cattcgtaat gaaagcatta
     7561 aaaaatgctt atataggaag aaagttaaag aagagagact tcagaaaact ttggatacaa
     7621 agaataaatg cagctgctag aatgaatgga atatcttatt caagattaat gaatggatta
     7681 aaattatctg gtattgaagt taacagaaag atgttatctg aaatggctat acaagaccca
     7741 gaaggatttg caaaattagc agaagttgct aaagcaaaat tagcttagta ttgaatcatg
     7801 agatgtaaag tctttgagtt atgtaaataa ttcaagggct tttttatttt ttgaaaaata
     7861 cttattagtg ccatatacat tcaattttat aatgataaat aaaataagag atacaataga
     7921 gtttgctcag atttaatata aaaattatta caattatcta taataactat agaaagttat
     7981 tttaaaaata acattgatat atgtataaag tttccagcta atcttgaatt aatattatca
     8041 atatgataat attatcttgt taagaatata tgtagaggga gagataatat gaatgataaa
     8101 ctgatggatt gttttgtaaa tccaattaaa tgcaagttat tacttgaaat tttttcaaat
     8161 aatagaacga cagctaaaca attaggagaa aaatttcaag atatatcaaa ggcaacactt
     8221 tatcgttacc ttaataaaat gttgaaagat gatattataa aagttgttga agaaaataaa
     8281 ataaggggaa ctgttgaaaa agtatatgct atgaagttag atatagctga tgatgttaac
     8341 aaaattatag atgagaactc tggagaagaa tatgctcaac tgttcactca atatatgatg
     8401 ggatttttaa gagaatttta tgaatatgct gaaagaaagg aaaaggatat cctaaaagat
     8461 ggttcagttt tttctgtctg tccagtatat gctagtattg acgagatagt tgaagcgagt
     8521 aaaaaaattg ctagtatact agaacctctg aaaaataatt cacatgaaga aggtagaaga
     8581 atgcattcta taggagtgat aattactcca cctaaagaag atgaaggtaa ataaatgata
     8641 aaagtaacag tttgattttt atgacaagct gttattttaa tgtatagtat tttatttata
     8701 atattttatt ttaatgtatg caataaaatg tatattaagc tggcatataa agtgatatga
     8761 tatatctaag ggaaaattgt atatatatga catatttaaa acacagggga tgaaaattat
     8821 gaggttaatt acacgttctg attttgacgg attagtatgt ggtgcattat taaaagaagc
     8881 ggggattatt gatagttgga agtttgctca tcctaaggat ttacaagatg gattggttga
     8941 ggtaacagaa gatgattgcc ttgcaaatgt accatttgtt gaggggtgtg gtctttggtt
     9001 tgaccatcac tctagtgaat ttgagagaaa taagcttgaa ggaagatata aaggtgaaag
     9061 tcgtattgct ccttcttgtg cgagaattat ttatgaatat tacggtggaa atgaaagatt
     9121 ttctcacttt aatgaaatgt tagaagcagt agacaaagtt gattctggaa atctcactat
     9181 agaagaggta caaaatccat ctggctggat tttaattggt tatcttatgg acccaagaac
     9241 aggattggga cgttggagaa attttactat atctaactac caattaatgg aaaagttgat
     9301 tgatgcatgt agaactttaa gtacaaaaga aattttagaa cttccagatg taaaggagcg
     9361 tatagaagtt tattttgagc aaacaaataa atttaaagag atgattgcta aatatacacg
     9421 tgtagaagga gatgttatta tttctgattt acgtggggta gagccaattt acacagggaa
     9481 tcgttttatg atttacagta tgtatccaga gcaaaatatt tctgcttgga ttgtaaatgg
     9541 taagggcgga aaagggtgtt ctgtagctgt tggatacagt attttaaata gaacttcgag
     9601 tgttgatgtt ggtagcctga tgcttaaata tggtggcggt ggacacaaag ctgttggaac
     9661 ttgccaattt aatgatgaac aaatagatga attgcttcca aagctacttg atgagcttgt
     9721 aaacactaaa aactagtgga taaacttata aattttaaaa actactacga ataaaataga
     9781 acttcattgt accatttcat ttaatgactt ggagtgatac aatgaagttt tttaattttt
     9841 catatcaata actaaagaaa taaactttag accacatata caattaggtt acattatacc
     9901 attagaacag atatataaaa taaaaaatca gtatttttat agcagacaaa ttgactgtta
     9961 ttctttttaa aagtcatata ttagttgttg ttagatggcg aaaaaaatta taggaaacta
    10021 ttgaataaat gaatattgcc tataatcata taaactgcta tagtttaaaa taaagcagaa
    10081 cgttaaattt tattataatc ttaaaattta agagggggat tttatgaaaa taaaatttgt
    10141 tattatgaca ttagtgatat ttttaatagc attactagtg ggatgtcaaa gtacaaaaga
    10201 tacagaagtt aaagtaaaag atacagaaat taaaatatta gggacaggtg atttacattc
    10261 aattttgaca gactctatgg tttcatatgt aaatgaggaa agggaaaaga ataaaaatct
    10321 gattatggta gatgcaggag atttctatgg tacacaaagt agagaaatgt gggagtggtc
    10381 ttctggaaaa aagttaatta atattagaag agatagtagg gcagagtatg atgacataat
    10441 taagaatagt aaagatgaag tacctatagt taaagagatg gcaaagttga aatatgatgc
    10501 tgtagttttg ggagataatg aatttgtttc aaatgataag caaagtcttg ataaactagt
    10561 ttctgatttt aaaaataata atatgccatt ggtatcagca aatatatatg aacaatctgg
    10621 agaaaattat gtacaaccat atgtaatgaa aaatattaag acagatgagg gcaatgtaaa
    10681 agttggaata ctaggtctta ctataaaaga agtaggggaa acccttggtc ttgaagattt
    10741 tgaaaaggat aaaaaagcaa gagcgttagg agaacaagct gattacaaag gaaaattata
    10801 tgcaaatgat ttaatagagg atgcaaagaa atggataaaa gttatgaaaa aagaaagtcc
    10861 agacataata gttgcagttg tacactcagg ggaagagcat aaaatggata gaaatccagg
    10921 aaatagaata aaagagttag caactacagt ggatggaata gatgtaattg tagctggtca
    10981 tactcatgaa aaaatagatg aacataaata taaaaataaa tctggagatg aagtaattgt
    11041 cacacaacca ggttggcatg gagatagagt gtcagagatt aatttcaaat taaataaaga
    11101 aaatgacaag tgggttataa aggaaaagtc tagtaaatta aaaatgattg attaaaaaat
    11161 agctacgcac acttgtgact ttagt
//
LOCUS       DBGJFK010000101        10338 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.106, whole genome shotgun sequence.
ACCESSION   DBGJFK010000101 DBGJFK010000000
VERSION     DBGJFK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10338
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.106"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(238..1023)
                     /locus_tag="ACOIAP_003324"
     CDS             complement(238..1023)
                     /locus_tag="ACOIAP_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGZ2640199.1"
                     /translation="MNFENDFITTEFKEKYIGLVLDNAQNINKVYTTTFPDKEIIKQV
                     IDKDEKDILIFSHHAMGYIASDEGFPFHDIPLSYMEEMKSRRISFYVLHSPLDNYSYY
                     STSVSFAKALGLEIVKPFCKYDDKIEVGVICKTSLKSIEEIKELIKKSVGHDVKLYDY
                     GDSVLKDGLVAIAAGGGSYPFVAREVAELGINLYITGFTKPLKHFEPVLEFHQIAKDN
                     LINVIGATHYSTEKFACMSMVNYFKNLGLESEFLQGKYYLEDL"
     gene            complement(1377..1847)
                     /locus_tag="ACOIAP_003325"
     CDS             complement(1377..1847)
                     /locus_tag="ACOIAP_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGZ2640200.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYQELFEQEIELDLGKNVTFRGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDNFDKFIEKLNSYKEVEFVHKPLKYEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLAEGYSAEETSKIIQHPIEFVKQCENSKQ"
     gene            complement(2341..2730)
                     /locus_tag="ACOIAP_003326"
     CDS             complement(2341..2730)
                     /locus_tag="ACOIAP_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2640201.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYKWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEEDV"
     gene            complement(3813..5219)
                     /locus_tag="ACOIAP_003327"
     CDS             complement(3813..5219)
                     /locus_tag="ACOIAP_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2640202.1"
                     /translation="MDSVKYILKRFIGSSILISLLFIILNIAGFLLFSYMIFVSKYSV
                     DLDTSDSREIKSNLIMLEENLILKDGKFILNDSSKEVLHKNKIWAMLINNNGDRVWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEYPNGILVTGYPKDKYTKFNLTYTIKE
                     IKQFPMLIICMFLVNAIVIFLIALFIGLKMVKSIKPIINGIKLISNGEPVILKEKGIL
                     SDISKSINTVSKELQMKDEKLRNKDEARSNWIAGISHDIRTPLSMIIGYAGELEESRN
                     LSNKEQEQVSIICNQGVKIRELVNDLNLVSKLEYNMQVLNCDKIRVSTFLRELVSEFI
                     NDNLDNDFYIELDILNEDIIVDADKKLLKRAISNLIQNSITHNQQGCNIKVISKSDLD
                     FCYIIVEDDGKGMSQEKINSLLKSQNGLSEAYAKGQNHGLGILIVAGIINAHGGKLDI
                     TSIDGKGLKTILKLPIIK"
     gene            complement(5264..5977)
                     /locus_tag="ACOIAP_003328"
     CDS             complement(5264..5977)
                     /locus_tag="ACOIAP_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640203.1"
                     /translation="MIVESIKDKKILVVDDHKELLKMIDEILRKEGFSRIFLASSCEE
                     AVRVFRNIKPDCAILDVVLPDGDGFSIMRKIRETSKMPVIFLSARGEDEDRLIGLGLG
                     ADDYIVKPFLPKELTLRLVSILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQE
                     ISLTAKEHSLLLKLYENKGRIVTSDSLCQAIWGDDMYGYENTLMVHIRRVREKIERTP
                     STPKYLLTVRGLGYKLMIN"
     gene            6132..7055
                     /locus_tag="ACOIAP_003329"
     CDS             6132..7055
                     /locus_tag="ACOIAP_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640204.1"
                     /translation="MKHMEMIIRTQRLSKEYNKIFRVKDIDLRVPKGAVYGFLGPNGA
                     GKSTTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENM
                     IIMQRLLDLPKKNINEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKLPKLLILD
                     EPTNGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQD
                     IIKELHNRGQSQIAIKTNNIVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINNML
                     VHSNIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            7055..7816
                     /locus_tag="ACOIAP_003330"
     CDS             7055..7816
                     /locus_tag="ACOIAP_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640205.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAISRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVASLNGIYL
                     SKFLCSAILVSVPVLIQVLSIVLFGYFRGVIESLSVFLLLKYILGTVFVNIAIIALHL
                     WIAIVIPNQMVAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDTNFSITILVFLIGILIYYIGRNHLLKKEV"
     gene            7828..8565
                     /locus_tag="ACOIAP_003331"
     CDS             7828..8565
                     /locus_tag="ACOIAP_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640206.1"
                     /translation="MLRKSVFGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSMLTAITQVFFVVFYIVAGNMFGFSGNIPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVANPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     AVCVSFITTIVFSEIANRNFRKNDVIS"
     gene            9045..9269
                     /locus_tag="ACOIAP_003332"
     CDS             9045..9269
                     /locus_tag="ACOIAP_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640207.1"
                     /translation="MEYSKGFKVIYSLVEYSKRFKAIYSVMEYSKGFKAIYDVMEYSK
                     GFKAIYDVVKYIQGDLNQSIVLLNIQRDLK"
     gene            9442..9711
                     /locus_tag="ACOIAP_003333"
     CDS             9442..9711
                     /locus_tag="ACOIAP_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HGZ2640208.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNTGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(9904..10149)
                     /gene="cdd1"
                     /locus_tag="ACOIAP_003334"
     CDS             complement(9904..10149)
                     /gene="cdd1"
                     /locus_tag="ACOIAP_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein Cdd1"
                     /protein_id="HGZ2640209.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFVSTENPEPEKLKWWYWKD"
BASE COUNT         3574 a         1523 c         1189 g         4052 t
ORIGIN      
        1 aattctaatc aatcataaat aataatctaa aatatatcaa aaaataaact taaaaacctc
       61 gaaaaagaac ttaaaagaca tcaaaactaa agcttctaat cagcaattaa aagtctattt
      121 tcttagttaa aaaaataaag atagattttt tcaaaacatt ggataaatgg gtaaaaaaaa
      181 taaacagtca gtaaaacaaa tttttaccaa ctgtttctct ttattattta atatatccta
      241 taaatcctcc aagtaatact ttccttgtaa aaattctgac tctaaaccta gatttttaaa
      301 ataattgacc atgctcatac atgcaaattt ttctgtagaa tagtgagttg cacctataac
      361 attaattaaa ttatcttttg ctatttgatg aaactctaac actggttcaa aatgttttaa
      421 aggtttagta aatccagtaa tatataggtt tataccaagt tcagcaactt ctcttgctac
      481 aaatggataa cttcctcccc ctgctgcaat agcaactaaa ccatctttta atacagaatc
      541 tccataatca tacaatttaa catcatgacc aacagatttt ttaattaatt ccttaatctc
      601 ttctattgat tttagtgatg tcttacatat aactcctacc tcaattttat cgtcatattt
      661 gcaaaatggt ttgactattt ctaaacctag ggcttttgca aaactaacag aagttgaata
      721 gtaactatag ttgtctagtg gagaatgtaa tacataaaaa gaaattctac gacttttcat
      781 ctcttccata taagatagtg gtatgtcgtg aaatggaaaa ccttcatctg atgctatgta
      841 tcccattgca tgatgtgaaa aaattaaaat atctttttca tctttatcta taacctgttt
      901 aattatctct ttatcaggaa aagtcgttgt gtatacttta ttaatatttt gagcattatc
      961 taatactaat cctatgtact tttctttaaa ttctgtagtg ataaaatcat tttcgaaatt
     1021 cataaaactc caatcatcat taatattttt aatattaaat tctaagtcta attttttata
     1081 aagttctatt gccttgataa taaccactcc tttataacaa caattgatta atacattact
     1141 aatataggaa tttcaggata ataaacttta tatatttaag tatttctact tcaaatttaa
     1201 aatattataa atattcaaat ttattaatat attttaatat cacatttatt tttcctttat
     1261 taatcttttc tctattttaa tttaatttat aacattagtc aaatactaat cctatatatt
     1321 atcttaaatt agttccacta caattaattt ctactaaata attataattt aaacaatcat
     1381 tgcttactat tttcacactg ctttacaaat tcaattggat gttgaattat tttagaagtt
     1441 tcttctgcag agtatccctc agctaaatac cttctagcta taacttccat agactctcct
     1501 atctcaataa tatgtttatc tgggtcataa atacgcacta ccctttgttg ccattcatat
     1561 tttagtggct tatgaacaaa ctctacttct ttgtaagaat tgagtttttc aataaatttg
     1621 tcaaaattat caacctcaaa ataaagttcc atattatttg atttttgtat aattgtatct
     1681 ggattaatcc ctgtaagcca tgcgaagtct tcttgtatgg caaatcctcc tctaaatgtt
     1741 acatttttac ctaagtccaa ctcaatctct tgctcaaata attcttggta aaattttttt
     1801 gatacttcga tatccttcac tgctaataat gaaacctgat atttcataaa ttttcctcct
     1861 aattgtttat ttgttcttta tttctatttt tttcaatatc ttctattaac acttttacct
     1921 atgtaacctc aatcccttct attaatcctt catttttact tttcagtatc ttttattaag
     1981 cccttatttt tactttttca acatcttata ttaacacttc acttctgtct cttcaatatc
     2041 ttcattaata gctatttatt ttatcatctt aagcttttac agtttatttt taaacttcta
     2101 tttaaatctc attgtcttca ttaaaaaagc tacctagtac ttatataatt ataggtagct
     2161 tttttaaatt taattaaata gaatatccat tactaattta tgtttacatt taacctgttt
     2221 tagattcaca ttataatgtt ataactcact tataataagt tattatatta cttaagtaga
     2281 ctaattatat aaatatatct acacacgatt tatattgatg ctatacaaaa atacgtttgc
     2341 ctatacatct tcctcctctt cttttagatt ttttatccac tcttcaataa gtaagatatc
     2401 atctttgctc agattaatat tttcatgtaa tgataataat aaacttttta tagaagaatc
     2461 atgaatattt ctaaaaaaat ctctagtttc aactcctatg tattcctttt ctttaattaa
     2521 aacttcataa tgtgtatatt tatctatctt ttgagaattt agaaatcttt ttactactaa
     2581 tctagataaa agagtcaaag ttgtcgtttg tttccattta tatttttgct ccattcctaa
     2641 aacaatatct ctagatgtta ctttggaatc tgatttccat ataaatttca ttatctttaa
     2701 ttctgattgt ggcaactttt ttatagtcat gataaaacct tgctactcag aatatagaca
     2761 agcaatatcc ataataaaat tcttcgatta aatacatctt atacggattt atataagctc
     2821 agatttataa gatatttttc aatcttaatc ctaaatttag ctatttgtac atggtaaata
     2881 tatataaata atgtcaaaat tttcgtatta tattgcttaa ttttatgaaa tattttgtac
     2941 tcagctatct attttggata cttgtccagt agctctcctt tcttttaaat tatttgattt
     3001 taaatatttg tattccagtg aatcctactt cctaaatttc ttacttaata caacttatta
     3061 ctaaacttcc tacttcctaa atttcttact tcttaagaat agtgttaatt gtaattttaa
     3121 gattataatt tttgccttgt ttaattgaaa cattctatat agttatatcc ttctatttta
     3181 gagttttttt atttatatct tacaaagttt aaattttttc attaattata ttataaatat
     3241 tctatatatt ttcatttaaa tatatatata tatatatgtt atttctaaaa atactacaca
     3301 aaactctact ttagtagaac ttaaagacgc aaaatacttc aatttaaaac atttatcgta
     3361 ctttaaataa ataactataa taaaatatac atacattagt tacataaaag ctattataac
     3421 tacacgtaac agcgtacaat taaaactttt ttagcatgtc attatatttt ttcttaaaat
     3481 taaaaaacac tatatcataa ttctatttta gtagaatttt tttgtcaata ataaaattaa
     3541 atattaatta aaaaataaaa aaaatggaat tatctaaaga atttaataac cttacaataa
     3601 ttccaaaata ttatttctat gaaaattttg ataccatgag taacttagct ataagcgcat
     3661 aaagcacaag ttactcttta gtttaataaa acttgacaag aaaagaattt atccttattc
     3721 tactctaata gagttacttt gtcaataaag aataaaatta ttttcaaaat atttccattc
     3781 ttcattttta tctgtcatta ttttataaaa tatcacttaa ttataggtaa ttttagtatt
     3841 gtttttagtc ccttaccatc aatactcgta atatccaatt tgcctccatg tgcattaata
     3901 ataccagcca ctatcaaaat acctagacca tgattttgac ctttagcata tgcctcactt
     3961 agtccatttt gactctttaa taaactatta attttttctt gactcatacc ttttccatca
     4021 tcttcgacaa ttatatagca aaaatctaaa tcagacttag atataacctt tatgttacac
     4081 ccttgttggt tgtgagttat actattttgt attaaattac taatagccct ttttaataat
     4141 tttttatctg catctacaat aatatcttca tttagtatat caagttcaat ataaaagtca
     4201 ttatccagat tatcatttat aaactcagaa acaagttctc tcaaaaacgt agaaactcta
     4261 atcttatcac aattcaatac ttgcatatta tattcaagtt tagacactaa attgaggtca
     4321 tttactaatt ctctaatttt aaccccttga ttgcatataa tagacacttg ctcttgctct
     4381 ttatttgaaa gattacggct ttcttcaagt tctccagcat atccaattat cattgaaagt
     4441 ggtgttctta tatcatgaga tattcctgca atccagttgg acctagcttc atctttgttc
     4501 ctaagctttt catctttcat ttgcaattct ttagatacag tattaataga ttttgaaatg
     4561 tcactcaata ttcccttttc tttgagaatt actggttcgc catttgatat aagctttatc
     4621 ccattaataa ttggttttat agatttcacc atttttaagc ctatgaatag agctattaaa
     4681 aaaataacta tcgcattaac cagaaacata catattatta acataggaaa ttgctttatt
     4741 tccttaatcg tataagtaag gttaaactta gtgtacttgt cctttggata acctgttact
     4801 aatattccat ttggatattc ccatacatac acaggataat cctttaaaaa gaaccttgaa
     4861 aactttgcta catctgtcaa agtataatga cttggaattt cttttggtaa atcaaatccc
     4921 catactctat ctccattgtt attaattaac attgcccaaa ttttattttt atgtagtact
     4981 tccttactag aatcgtttaa aataaacttt ccatctttta aaatcaaatt ttcttcaagc
     5041 ataatcaagt tggattttat ttccctacta tcacttgtat ctaaatcaac agagtatttg
     5101 gatacaaata tcatatatga aaacagaaga aaacctgcta tatttaatat aataaaaagt
     5161 aatgaaatca ggatacttga acctataaat cgcttcaata tatactttac actatccaaa
     5221 attaaatcac tcctcttgat ttcttttatc ctaatagcta aaattaatta atcatcaact
     5281 tatatccaag acctcttact gtaagaagat atttaggtgt agatggagtt ctttctatct
     5341 tctctctaac ccttctaata tgaaccataa gggtattttc atatccatac atatcatccc
     5401 cccaaatagc ttgacatagt gaatcactcg taacaattct acctttattt tcatacaact
     5461 ttaaaagcag tgaatgctct ttagctgtta gagaaatctc ttgcccatct ttctcaacac
     5521 atgcactatt taaatttaca acaacagaat ctcccagttt aaatactggt aactcttctt
     5581 cttctatagg cacatataca cgatttaata tgctcacaag tcttaaagta agttcctttg
     5641 gtaaaaatgg ctttactata taatcatcag ctcctaagcc caaaccaatc aatctatcct
     5701 catcttcgcc tcttgcagaa agaaaaataa ctggcatttt agatgtctct ctaatttttc
     5761 tcataataga gaaaccatct ccatctggca atacaacatc taaaattgca caatctggct
     5821 ttatatttct aaatacccta acagcttctt cacaacttga tgctaaaaat attctactaa
     5881 atccctcttt tcttaggatt tcatctatca tttttaataa ttccttgtgg tcatcaacca
     5941 caagtatttt tttatctttt attgactcca caatcatcac cctcctttag tataccatat
     6001 accattttca cagctttgcc taaatagact atttaaggct attgtaaggt aaacttcagc
     6061 taattgaaat gtagttcatt tattatactt atataagcta aaaaaatcaa taaacacaga
     6121 ttaaaaaggg gatgaaacat atggaaatga taattagaac acaaagactt tcaaaagagt
     6181 acaataaaat atttagagta aaggatatag acctaagagt tccaaaagga gctgtatacg
     6241 gttttttagg tcctaatgga gccggaaaat ctaccactct taaaatgctt cttggacttg
     6301 ctaaacccac acaaggaaat attaatattt taggtaaaga attaaatgaa aaaaatagaa
     6361 tatcaatttt aaaagatata ggttctttaa tagaatctcc atcatactat ggtcacctga
     6421 cagggcttga aaacatgatt ataatgcaaa gactcttaga tttgcctaaa aaaaatataa
     6481 atgaagcatt aaaaattgta aggttagaaa atcaaaaaaa taaaaaagtt agtcaatatt
     6541 ctttaggtat gaagcaacgt cttggcattg ccatggctat aatgaaactt cctaagttat
     6601 taatacttga tgaacctaca aatggacttg acccagcagg tattgaggaa attagagaat
     6661 taataaaatc tctaccagaa aaatacggta tgacagttct aatctctagc catcttttaa
     6721 gtgaaattga ccaaattgcc acatcaatag gaataataaa tcatggcgaa ctggtttttc
     6781 aagatatcat aaaagaactt cataatagag gtcaaagtca gattgctatc aaaactaata
     6841 atattgtatc tgcacaaaag ctattgaata ctaaaggata tatgtcactt atacaagatg
     6901 gatatttaac tattgaaaat ttaaaagact cagatgttgc taaaataaac aatatgcttg
     6961 tccattcaaa tatagatgta ttcagaatag aagaacataa aaagagcttg gaagatatct
     7021 tcctagaact tactggtaag gcggtgactt tataatgaaa taccttggtc tagaatttta
     7081 taaacttaaa agaaagaaga ttattctgat gaccttttta tttgtagctg ttgaaataat
     7141 gtggtgcatc ataaattcaa atagagctat ttcacgtaat ccagatatgt taggtggatt
     7201 tgaatattca tatatgctta tgagttttgc aagtttaaat ggtctattct ttcctatctt
     7261 aatatcaata attacatcac gtataagcga tatagaacat aaaggagata catggaagct
     7321 tttaaaatct tctgtggcat ccttaaatgg tatttattta tctaaatttt tatgctctgc
     7381 tattttggta tctgtacctg tattgataca agtgttgtct attgtgctat ttggatattt
     7441 tagaggagta atcgagtcac tttctgtctt tttactttta aaatatatat taggaacagt
     7501 ttttgtaaat attgctatca ttgcactgca cctatggatt gcaattgtaa ttccaaatca
     7561 aatggttgca attacatttg gtatgattgg cagttttata ggtttgacat caggattgtt
     7621 ttatcaaggt attcgtagat tgtttatatg gtcttattac ctagagttat cacctttaag
     7681 ttacgcttat gataatgttt taggttcatc tgtttataga attgatacga atttttctat
     7741 tacgatttta gttttcttaa ttggaatatt aatttattat attggaagaa atcatttatt
     7801 aaaaaaagaa gtataggagg gatttaaatg ttaaggaaat cagtttttgg agaaattcta
     7861 aagttaaaaa attcttttat atggtatgta ttattagctt tgccacttat aagtgtattg
     7921 attggctctg gtaattttta tctaaatcaa ggcatactca aaaaagaatg gtacagctta
     7981 tggactcaag ttagtctttt ttatggggaa tttttctttc ctatcttaat cgcaatcttt
     8041 tgtgcatata tttgtaggct tgaacatatg aatcataatt ggaataatgt aatgacattg
     8101 ccagttaatt taaaaaatat ctttttatct aaacttacag tagtttcaat gcttacagct
     8161 attacacaag ttttctttgt tgtcttttat attgttgcag gaaatatgtt tggtttttct
     8221 ggtaatatac ctaaagaatt gactggttgg attgctaaag gttggattat ttccatttca
     8281 atagcttcta tacagttata catgtctata aagattagaa gttttgcaac acctattggt
     8341 attagtcttt gcctttcttt atttggtatg ggattaatag tagcaaatcc tgctgttggt
     8401 atatttttcc cttattctat gttaggtagt gctatggggg ttataaagca atctgcttta
     8461 aatgttaatg acactatagt tgcagtatgt gtttcattta ttactactat agtattttct
     8521 gaaattgcca atagaaattt tagaaagaat gatgttattt cttaatggta aacgttagat
     8581 atttttttgt ttaaaattta tattcttttt agttgaaata tatatccctt ttagttaaaa
     8641 atctatatct tttattttaa ttttatatgt tttatctatc tactatataa taaatatact
     8701 cctaaaagta aaaaatatat aataatgtta ttatttaaaa ttattatata ttatattaaa
     8761 acttaatgca aaaacaattt ttatattata taatgaaact taattaaata taactaaaaa
     8821 atcattaaat atattaaata aatatttaac tttaatgacc tatatttaat tatggctata
     8881 acatagaatt atcaaatata ttgaataaat atttgaccct tgaaatgtgt aattaaatta
     8941 agtttggtta tttgatggaa tgcaaatttg atataaaaac tccatttaaa gtgccagata
     9001 aaaactttat ggttatataa aagctaaaag taatttatag tgttatggaa tattcaaagg
     9061 gatttaaagt aatctatagt cttgtggaat attcaaagag atttaaagca atctatagtg
     9121 ttatggaata ttcaaaggga tttaaagcaa tctatgatgt tatggaatat tcaaagggat
     9181 ttaaagcaat ctatgatgtt gtgaaatata ttcaagggga tttaaatcaa tctatagttt
     9241 tactaaatat tcaaagggat ttgaagtaat ttattgtgtt ttgaaatatt caaaaatatt
     9301 tttggaatag tttttataaa tttaccagta ctaataattt tatgtttaac gtttagatga
     9361 cttaaaatca attatttgca cttttgtagt catctaaagt tattttataa tatttttaaa
     9421 taatggaaag gatgtttgaa tatgtttgaa tcaagatgtg gtgtctgttg tgacagttgt
     9481 acaaaaaaag aacaagtaaa ttgtactggt tgcccaacta tggaaaaacc attttggggt
     9541 ggagaatgta aggttaaaac ttgctgtgaa agtaaggaac ttaatcattg tggtgaatgt
     9601 gatactttcc cttgtgatat gcttttaaat acgggaaaag accaaggttt tgaccctatg
     9661 gtaaatattg agcaatgcag aaaatggctt gaagaaacag tttctaatta attgttttag
     9721 aatgttttgt taagcaattt atttaatact ttgttagata gtatgtttag tcatttgttg
     9781 attggtatat ttagccatac aaatagattt acataaaatt tacgactaaa aaagagttga
     9841 gtattagttt ttattattaa aacagatatt caactctttt ttatatctaa cttttttgat
     9901 tttttaatct ttccaatacc accactttaa tttttctggt tctggatttt cagttgatac
     9961 aaaatatact gcacatctgt atacatataa ctgacatctg tctatgtgtt gtccacgcat
    10021 taaacattcc ttttcataca tttgtgctgg gtttgcatct ttaagtgatt taatagttgt
    10081 atatcctaac atgattaaag atttttctgt tgctttccct acccctggaa ttttttgtag
    10141 ttctcccata cttcaccttc tttctggtat attatttttg tattatactt agtaccagat
    10201 atttttttat tatagttaat atttaatttt ttattatatc aatttattta tgctctttca
    10261 tctatctata ttttaccacc tctaaagtac tgagtcattt aattacatca taatatagtt
    10321 ttatacaaat aaaatact
//
LOCUS       DBGJFK010000102         9915 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.107, whole genome shotgun sequence.
ACCESSION   DBGJFK010000102 DBGJFK010000000
VERSION     DBGJFK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.107"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            190..2061
                     /locus_tag="ACOIAP_003335"
     CDS             190..2061
                     /locus_tag="ACOIAP_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HGZ2640210.1"
                     /translation="MNRKNLSVIMATAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGENLSKLKVITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEAIEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTGTVTSKTIEVGIGDEKVDLTANPIDSTGTNLDPSAEGFRVNKINK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVVNGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKAIELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNVVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGYDRHTTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSSDAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKSALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            2168..2875
                     /locus_tag="ACOIAP_003336"
     CDS             2168..2875
                     /locus_tag="ACOIAP_003336"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGZ2640211.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGTCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELNKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKRWNPESGHYAIGYHSVK
                     SHFDELATNKIQYVHAP"
     gene            2908..4740
                     /locus_tag="ACOIAP_003337"
     CDS             2908..4740
                     /locus_tag="ACOIAP_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HGZ2640212.1"
                     /translation="MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWSKSDTAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENINFERISGNSRYDTSLKLAEKLNKEKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERNLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRNKNDLIDSLAVGV
                     LAAKNSSPIVLAGNKLDTTQKDVLNTKVIDKVTQIGGLGNEDAVKSIIDMQEKTKYTI
                     ETIDELNVAIKKADANDVIIFEPEKDTSISDSFKIETNKAITVEFDGVFKKSITIDMP
                     NGDVKNFGEISDDIRIDNIKKGTLINEGSIQGIDIYSKNGCKIENTSDGDIWIITIDA
                     DAKDVYIENDGDITKISNNAPGVIIKNSGKIDLVNGNEQPAISGKKPTTNDTEYNDER
                     ARGLSVSTKPCSIPEKDRVRVTISSEPKSSRYKIYYRVVEDKPSAMYVGEKISVRSWD
                     LASKSDGSFVEKAKNGSYIEVVEINTSTNKVSRWGRSNVTDDGF"
     gene            complement(4787..5188)
                     /locus_tag="ACOIAP_003338"
     CDS             complement(4787..5188)
                     /locus_tag="ACOIAP_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGZ2640213.1"
                     /translation="MILKKHKETILYLFFGAFTTLVNIVSYLFFTRVISFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIELRFLFKEFFSFVSFRLLSGVIEMVIMYIMIDLLF
                     VNDIIVKVFTNIVVIVLNYLFSKMIIFKNKK"
     gene            5416..7827
                     /locus_tag="ACOIAP_003339"
     CDS             5416..7827
                     /locus_tag="ACOIAP_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HGZ2640214.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENNKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRSKSRSSLPSSYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATRPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHSVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKSELQRLGTKKVYLIGGEDSLSKNVQAQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKRQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKTVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            8130..9707
                     /locus_tag="ACOIAP_003340"
     CDS             8130..9707
                     /locus_tag="ACOIAP_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HGZ2640215.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLVGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERLSGKDRNETNAKVIEKFYSDTSLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLSTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKEDTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKIN
                     KIQDILDKLGFLKKFLS"
BASE COUNT         4139 a         1150 c         1771 g         2855 t
ORIGIN      
        1 aaaaaaatta cagttttgtt acttttttgt atacataaat attaaaaatt taaagtatta
       61 gaaaaaattt atatcttttg gttaattatt acaataagtc tcatttattg aaataatatc
      121 aaatatatat tataattggt aaataaggaa aaaatgataa aaaattgaat tttttagggg
      181 gaaaatacca tgaatagaaa aaatctttct gtaattatgg ctactgcaat gataagtaca
      241 tcagtagctc cagtttttgc tgcagaaact acacaggtaa aaaaagaaac aataactaag
      301 aaagaagcta cagaactagt ttcaaaagtt agagatttaa tgtctcaaaa gtatacagga
      361 ggttctcaag ttggacaacc aatatatgaa ataaaagttg gtgagaattt atcaaaatta
      421 aaagtaataa ctaatataga cgaattagag aaattagtaa atgctttggg agaaaataaa
      481 gaacttattg taactataac agataaaggg catataacaa atagtgcaaa tgaagtagtt
      541 gcagaagcaa ttgaaaaata tgaaaattca gcagaccttt ccgctgaagc taattctata
      601 acagaaaaag ctaaaactga aactaatgga atttataaag ttgcagatgt aaaagcttca
      661 tatgatagtg ctaaagataa gttagttata actttaagag ataaaacagg aacagtaact
      721 tctaaaacta tagaggtagg tattggtgat gaaaaagttg atttaacagc aaatccaatt
      781 gattcaactg gaacaaactt agacccttct gcagaaggat ttagagtaaa taaaatcaat
      841 aaactaggtg tagcaggagc taaaaatatt gatgatgttc aattagctga aataactata
      901 aaaaatagtg acctaaatac agtttcacca caagatttat atgatggata tagattaact
      961 gttaaaggta atatggtagt aaatggtaca tcaaagtcaa ttagtgatat ttcagcaaaa
     1021 gattcagaaa caggaaaata taaatttact attaagtata ctgatgcatc tggaaaagca
     1081 atagagctta ctgtagaaag cactaatgaa aaagatttaa aagatgccaa ggctgcatta
     1141 gaaggtaatt caaaggttaa attgatagct ggagatgata gatatgcaac tgcagtggct
     1201 atagcaaaac aaacaaaata tactgacaat gtagttatag ttaattcaaa taaactagtt
     1261 gacggattag cagctacacc actcgctcaa tctaaaaaag cacctatatt gttagcatct
     1321 gataatgaaa taccaaaagt aactttagat tatataaaag atataattaa gaaaagccca
     1381 tcagctaaaa tatatatagt aggtggagag tcagcagtat caaatacagc taaaaagcaa
     1441 ttagaatcag taactaagaa tgttgaaaga ctagctggat atgatagaca tacgacttct
     1501 gtagcagtag caaaagctat ggggtctttt aaagatgcat ttgtagtagg tgcaaaaggg
     1561 gaggctgatg ctatgagtat agctgctaaa gctgctgaac ttaaggctcc tataatagta
     1621 aatggctgga atgatctttc atcagatgct atcaaactga tggatggaaa agagattggc
     1681 atagttggtg gttctaacaa tgtatctagt caaattgaaa atcaacttgc tgatattgat
     1741 aaagatagaa aagttcaaag agttgaagga gaaacaagac acgataccaa tgctaaagtt
     1801 atagaaacat attatggaaa attagataaa ctatatatag caaaagatgg atatggaaat
     1861 aatggtatgc tagtagatgc attggcagca ggacctctag cagcaggtaa aggtccaata
     1921 cttctagcta aaactgatat aacagactca caaaagagtg cacttagtaa aaaattaaat
     1981 cttggtgcag aagtaactca aataggtaat ggagttgaat tgacagtaat acaaaagata
     2041 gctaaaatac taggttggta ataacttata ctgtggagaa gattccttaa taaatacagg
     2101 aatctttttc tataactatg ctatttattg taaattataa cattttatga agtaggagga
     2161 tgtagtagtg gtagatgcaa ctttattttt tacaccacat caagatgatg aaactttaag
     2221 tatgggaagt gctataattg aacatgttga aaaaagtgat acacatgtca tattatgtac
     2281 agatggtagt aaatctataa taagaaaagt tttggatgat ggaggcacat gttcttatca
     2341 tattaaagat gtacataaat attctttatc agaaagtgaa ttttcaaaag atagagatga
     2401 agaatttaag gatagttgtg aagcaatggg tgtaaaagaa agtaatatac atatagaaga
     2461 taatagagcc catgatggcg agttaaataa agaaaaggca agggaaataa tacttaagta
     2521 cttagaagaa tatccagatg caaaagtaaa aacggttact ccgtttaaag ctagtggaat
     2581 acatgaagac catagagcat taggagaagc tgcactagag ttatatagag aaggaaaaat
     2641 aaaagattta agattttatg tagaaccata tgactataag gattttaaaa aagttaatcc
     2701 aaatgtagag gtatggaagg tattacctag tcaagaagag aagttattaa gtgcaatgaa
     2761 tgcatataag agatggaatc ctgaaagtgg acattatgct ataggatacc attcagtaaa
     2821 atctcatttt gatgagttag ctacaaataa aatacagtat gtacatgctc cataaaatat
     2881 tacgaaagaa ttaggaggta agaattaatg aaaatatcaa aaaagatagt gtctttgtta
     2941 actatgacat ttttaactgt tacattatat ggaaatacat ctaatgcatc tacaaaagac
     3001 acattaacag gttctggaag atgggaaaca gcaataaaaa taagtcaagc tgggtggtca
     3061 aagtctgata cagctgtatt agtaaatgac aattccatag cagatgcttt atcagctact
     3121 ccatttgcaa aagcaaaaga tgcaccaata ttattaactc aaagtaataa attagatagt
     3181 agaaccaaag cagaattaaa aagacttggt gtaaaaaatg tatatttaat aggaggttca
     3241 attgcattaa gttcagagat tgaaaagcaa ttaaatgcgg aaaatataaa ttttgaaaga
     3301 atatctggaa atagtagata tgatacttct ttaaaactag ctgaaaagtt aaataaggaa
     3361 aaatctatct ctaaaatagt agtagtaaat ggagaaaagg gacttgctga tgcagtaagt
     3421 gttggagcta tagctgctca agaaaatatg ccaataatac tttctgattc agagaatgga
     3481 actgaagtag ctgataattt tatagatagt aaagatatag aaaaatcgta tgtaataggt
     3541 ggtacatatt ctatttctaa ttctgtagaa agaaatttac caaatgcaac aagaatagca
     3601 ggcagtagta gaagtgaaac aaatgcaaag attatagaag aattttataa agatactgac
     3661 ataaaaaata tttatgttac aaaagatggt acaagaaata agaatgattt aatagattct
     3721 ttagcagtgg gtgtattagc agctaaaaat agttctccaa tagtattagc aggaaataag
     3781 cttgatacta ctcaaaaaga tgtgttaaat actaaggtta tagataaagt tactcaaatt
     3841 ggtggtttag ggaatgaaga tgctgtaaaa agcataatag atatgcaaga gaagactaaa
     3901 tatactatag aaactattga tgagttaaat gttgctataa aaaaggcaga tgcaaatgat
     3961 gtaataatat ttgaaccaga gaaagatact agtataagtg attcattcaa gatagaaaca
     4021 aataaagcta taactgtaga atttgatgga gtatttaaaa aatctataac tatagacatg
     4081 cctaatggag atgtaaagaa ttttggagaa atttcagatg acataagaat agataatata
     4141 aagaaaggta ctttgattaa tgaaggtagt atacaaggta tagatattta ttctaagaat
     4201 gggtgtaaga tagaaaatac aagtgatgga gatatatgga ttataactat agatgctgat
     4261 gctaaagatg tatatataga aaatgatgga gacataacaa aaatatcaaa taatgctcca
     4321 ggtgttataa taaaaaattc aggaaagatt gatttagtaa atggtaatga gcaacctgca
     4381 attagtggaa agaaaccaac aactaatgat actgaatata atgatgaaag agcgcgtgga
     4441 ttgtctgtta gtacaaagcc ttgctcaata cctgaaaaag atcgtgtaag agtgacgata
     4501 tctagtgaac ctaagagttc aagatataaa atttattata gagttgtaga agataaacct
     4561 tctgctatgt atgtaggaga aaaaattagt gtaagaagtt gggacttagc atcaaaatca
     4621 gatggatctt ttgtagaaaa agctaaaaat ggatcatata tagaagttgt tgaaataaat
     4681 acctcaacta ataaagtttc tagatgggga agatcaaatg taactgatga tggattttaa
     4741 atcaccttaa ataaagttaa aaaagtagat tactatttct agtagtctac tttttatttt
     4801 taaaaattat catcttacta aacaaataat ttaaaactat aacaactata ttagtaaata
     4861 cttttacaat aatatcattt acaaaaagta aatcaatcat tatatacata ataaccattt
     4921 ctataacacc agaaagtagc ctaaaactaa caaaagaaaa aaattcctta aacaaaaatc
     4981 ttagttcgat tcttttactt tcaaacacaa aaaacttatt agtaacataa gcaaataaaa
     5041 cagcaagtat ccatgccaaa gcatttgcaa ccataaaatt aaatgaaata actctagtaa
     5101 aaaataaata cgaaactata tttacaagag tagtaaatgc tccaaaaaat aaatataata
     5161 ttgtctcctt atgctttttt aaaatcaaat ataatcctcc taagctaatt taatataaat
     5221 atacttaaag atactaacaa acattagtat agcacatcta tcaataaatc aatatatctt
     5281 aaaatattat aaaaaataaa actataatat tctataatta atacgtactc ataatccata
     5341 ttttatcaaa ataaaatatg accttaattt agaaatctga tataataaaa attaaataca
     5401 tataaggggg taaacatgag aaagtacaaa tcaaaaaaat tgtcaaagct actggcattg
     5461 ttgacagttt gctttttaat agtgtcaaca atacctgtct cagcagaaaa caataaaact
     5521 ctagatggag tagaaactgc agagtattct gaaagctatc ttcaatacct agaagatgtc
     5581 aaaaatggag acacagcaaa atataatgga gtaatacctt ttccacatga aatggaaggt
     5641 acaacacttc gaagtaagag tagaagtagt cttccatcat catacaaatc aagtgtagca
     5701 tacaacccaa tgaatcttgg tcttactaca ccagcaaaaa atcaaggaag tcttaataca
     5761 tgctggtctt tttcaggtat gtcaacttta gaagcatatc ttaaattaaa gggatatgga
     5821 acgtatgact tatcagaaga acatttaaga tggtgggcaa ctggtggaaa atatggatgg
     5881 aacttagatg atatgtcagg tagttcaaat gtaacagcca taggatatct gacagcatgg
     5941 gcaggtccta agttagaaaa agatatacca tataatctta aatctgaggc gcaaggtgca
     6001 actagacctt caaatatgga tactgcacct acacaattta atgtaacaga tgttgttcgt
     6061 cttaataaag ataaggaaac tgtaaaaaat gctataatgc aatatggttc agtgacatca
     6121 ggttatgcac attattcaac atattttaat aaagatgaaa cagcatataa ctgtacaaat
     6181 aagagagctc cattaaatca ctctgtagcg atagtaggat gggatgataa ttattcaaaa
     6241 gataactttg catctgatgt aaaaccagaa tcaaatggag catggttagt aaaaagcagt
     6301 tggggagagt ttaattctat gaaaggattc ttctggattt cttatgaaga taaaactcta
     6361 ctaacagata cagataacta tgcaatgaaa tcagtatcaa aaccagatag tgataaaaaa
     6421 atgtaccaac ttgaatatgc tggtcttagc aagataatgt caaataaagt aacagcagca
     6481 aatgtatttg attttagcag agattctgaa aaacttgatt ctgttatgtt tgaaacagac
     6541 tctgtaggag caaaatatga agtatattat gcaccagtag taaatggagt tcctcaaaat
     6601 aattcaatga caaaacttgc aagtggaaca gtatcatatt ctggatacat aaatgtacct
     6661 actaattctt acagcttacc aaaaggtaaa ggagcaatag tagtagttat agacaacaca
     6721 gcaaatccta atagagaaaa atcaacttta gcatatgaaa ctaatataga tgcatattat
     6781 ttatatgaag ctaaagcaaa cttaggtgaa agttacatac ttcaaaacaa taaatttgaa
     6841 gatataaata catatagtga attttctcct tgtaactttg ttataaaagc tataacaaaa
     6901 acatcttctg gacaagctac ttcaggagaa tctttaactg gagcagatag atatgaaaca
     6961 gcagttaaag ttagtcaaaa aggatggact tcttcacaaa atgcagtatt agtaaatgga
     7021 gacgcaatag tggatgcttt aacagctaca ccatttacag cagcaatcga ctctccaatt
     7081 cttttaacag gaaaagataa cttagattca aaaactaagt cagagttaca aagattagga
     7141 actaaaaaag tttatctaat aggtggagaa gattctttaa gtaagaatgt acaagctcaa
     7201 cttagcaata tgggtatatc agtagaaaga atttcaggta gtgatagata caagactagt
     7261 atatctctag ctcaaaagct aaatagtata aaatctgttt cacaagttgc agtggcaaat
     7321 ggtgtaaatg gacttgcaga tgcaataagt gttggtgcag cagcagctga taacaatatg
     7381 ccaataatac ttactaatga aaagagtgag ttgcaaggtg ctgatgagtt tttaaattca
     7441 tcaaaaataa ctaagtctta tataattggt ggcacagcta ctttatcatc aaatttagaa
     7501 agtaagcttt caaatccaac aagacttgca ggaagtaata gaaatgaaac taatgctaag
     7561 ataatagata aattctaccc tagttcagat ttaaaatatg cttttgttgt taaagatggt
     7621 tcaaagcgtc aaggagattt gatagatgga ctagcagtag gagcattagg tgctaaaact
     7681 gattcaccag tagttctagt tggaaataag ttagatgaaa gtcaaaaaac tgtacttaag
     7741 tctaagaaaa tagaaactcc tattagagtt ggtggaaatg gaaatgaaag tgcttttaat
     7801 gaactaaata ctcttttagg aaaatagtga atagaaagat agtaaggata tacattttat
     7861 tattaaaaaa tattcaatag aagtttataa atataaaata acaaaaaggg gtgtctcaaa
     7921 atgaactttt tagtccatga ggcactcttt tttgtatgaa ttcaaatata ttttcatcat
     7981 ttcaacaatg gaaaatagga ttgtctatat tttgagatag cctctttatt attgatgaaa
     8041 aatgtaataa ttttaaactg taaaatagtg taaagttatt ttataatata aatatagtaa
     8101 gattttaaac aaaataagga ggaataataa tgaaagcacc aaaaactatt ttaacaatac
     8161 tgacaatagc gcttacttta agtagcattt ctataatacc atcatatgca cttacagagg
     8221 aaaaattagt aggtaatggt agatatgaaa ctgctgtaaa gataagtcaa aaggcataca
     8281 gttctagttc taatgtagtg ttagttaatg ataattcatt agctgatgca ctttcagcta
     8341 caccatttgc aaaggctaaa ggagcaccaa tacttttgac agaaagtgat aaactagatg
     8401 atagaactga aaaagagata aaacgtctag gagctaaaga tatttattta ataggaggta
     8461 ctgctgtact taataaagat atagagaaca aattaaaagg taatggactt aatgtagaaa
     8521 gaattaatgg taaggataga tatgaaactt cactaatttt ggctaataag cttaaggata
     8581 taaaagatat taaagaagtt gctgtagtaa atggtgaaaa aggactgagt gatgctgtta
     8641 gtgttggagc accagcagct caaaataaga tgcctataat tttgtctagt cctaaggatg
     8701 gagtagaagc atttgataaa tttataagag atgagaaagt tataaaagca tatgtaattg
     8761 gagggacaaa ttcagtttca agagctgtag aaaagagtct tcctaatgca gaaagattaa
     8821 gtggaaaaga tagaaatgag actaatgcta aagttataga aaagttttat tctgatacaa
     8881 gtttaagtaa tctatatgta actaaggatg gaagcaaaaa tgaaaatcaa ctgatagact
     8941 cattagcagt tggagtgctg gctgcaaaaa atgaatctcc tgttgttttg gttggcaata
     9001 aattaaacac aaaacaaagg gatatactta gtactaaaaa attaagtact ataacacagg
     9061 taggtggaaa tggaaatgaa gaagcttttg atgagattaa aagtttacaa gaaaaaactg
     9121 tgtttgaagc aaaaactgtt gaggaattaa ctgatatgat aaatatagca agtcctaatg
     9181 acattataaa ttttaaacca aaagaagata ctgtaaatga agcttttaga atggtgacaa
     9241 ataaaccaat aactgtgaat ataaaaggag attgttcaaa aactcttaca gtagatatgc
     9301 ctaatggtga agtgaataac tatgctactt tggtaaatgt tatagttaga aatattggag
     9361 aaggtggatt taataatcat gatacaatca ccatattgtc agttcgtgac aaaaatggta
     9421 gagttataga aaatactaga aattcagata tagatacgtt gatgatatta gcttctgcta
     9481 atgatacaaa attgattaat gatggatata taggaaagct tatagataat tcatctaata
     9541 gtgatataac taataatggt actatagata aaaaagttaa tcaggttgag gatttagagg
     9601 ctaaggttga ttcaattgaa aaagctatag attctataag tcagaaaatc aataaaatac
     9661 aagatatact agataagctt ggatttctaa agaaatttct tagctaaaaa tatgtatatt
     9721 taagtgaact gtgtgttgga attatatctg aagatatata gttaaatggg tttatagata
     9781 aataggctta tagctaaata tatagttcaa tatatagtta aataaatctt ggggaggtaa
     9841 catggggagc ggaattgaat gtaacaaaag aatacataaa agtattgaca aaactagaat
     9901 aaagaaaaat aatct
//
LOCUS       DBGJFK010000103         9848 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.108, whole genome shotgun sequence.
ACCESSION   DBGJFK010000103 DBGJFK010000000
VERSION     DBGJFK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9848
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.108"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(384..881)
                     /locus_tag="ACOIAP_003341"
     CDS             complement(384..881)
                     /locus_tag="ACOIAP_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HGZ2640216.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELKENESVTATDFVQGTTSWHGKLGG
                     LDRLDASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
     gene            complement(987..1349)
                     /locus_tag="ACOIAP_003342"
     CDS             complement(987..1349)
                     /locus_tag="ACOIAP_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGZ2640217.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYKGYPLKVEYSLTPIRGKQILDALAIMQDIGIN
                     FMLDNGMEDILKEKGVLK"
     gene            complement(1367..1981)
                     /locus_tag="ACOIAP_003343"
     CDS             complement(1367..1981)
                     /locus_tag="ACOIAP_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HGZ2640218.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     LGNALRDISKKYPDLIKKELDSWDISNKKVEFVYKLASKRILAK"
     gene            2582..4717
                     /gene="rnr"
                     /locus_tag="ACOIAP_003344"
     CDS             2582..4717
                     /gene="rnr"
                     /locus_tag="ACOIAP_003344"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGZ2640219.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIISPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLS
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEVLARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYVYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            5856..6347
                     /locus_tag="ACOIAP_003345"
     CDS             5856..6347
                     /locus_tag="ACOIAP_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HGZ2640220.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDSNENSTINIDKA
                     WHAIHFTLTGCPFGGDEDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQEFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKRFIQEASDDGQAVIF
                     FIM"
     gene            6374..6547
                     /locus_tag="ACOIAP_003346"
     CDS             6374..6547
                     /locus_tag="ACOIAP_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640221.1"
                     /translation="MSSHILDMKTIEKYIKEMIGESISEINSLWKTGESIKINYSKVS
                     SERFEEIIQRVTP"
     gene            6759..6959
                     /locus_tag="ACOIAP_003347"
     CDS             6759..6959
                     /locus_tag="ACOIAP_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640222.1"
                     /translation="MSIFGNFALAMSIGSLGMFFSNLFNNTIIGYMVSMGYLILNMMT
                     KGKYVGNFFIMSMSQSSFDEKY"
     gene            complement(7306..7770)
                     /locus_tag="ACOIAP_003348"
     CDS             complement(7306..7770)
                     /locus_tag="ACOIAP_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HGZ2640223.1"
                     /translation="MNLNKVKFTEEHAIEVINWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDRRKNFISFINDNKELIGFINLLDEGSSVFFGIGIKPEYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKRQKTYLGDGEFFVMRYQ"
     gene            complement(8782..9609)
                     /locus_tag="ACOIAP_003349"
     CDS             complement(8782..9609)
                     /locus_tag="ACOIAP_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HGZ2640224.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPMMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGTMPTNDNMNNKVSKQK"
BASE COUNT         3806 a         1189 c         1361 g         3492 t
ORIGIN      
        1 tgggttatta aattttatat agattgataa tgtctataaa aattattaat ttttatgtcg
       61 attgataaat tttatataag ttattgcatt tcatttagat tataaaactt tatgtagagt
      121 tactgagttt aacatatatt attatttata ttaatgcttt tattttaatg agtttaataa
      181 tatttctaat agaaataaaa atatgtaagc aagttttaag ctaaaatcag gttatataaa
      241 ttgataataa tctaatggaa attaaaatac caataaatta aaatataaat taatataata
      301 tgtaaaaaat attctaataa caattaagct aatcatcaat taaatgtagg cacttaatta
      361 atgattagct atagtcaatc taattaatta gaataacttc cttttagtgt aaatgtatct
      421 aaaacatgtc cttcaatagc tttgaaaaat tcattcatat agaatccttt ttcaaggtca
      481 aggatggtat caagtgcaaa tacatgtatt tcatagacat gaggtctgtc tggaggtgcc
      541 attccaccat atacactggc atccaatcta tcaagacctc ctagtttacc atgccagcta
      601 gtagtccctt gtacaaaatc agtggctgtt acactttcat tttcctttaa ctcatctttt
      661 gttatattta cagctaacca gtgtatccat gcaaacccac acacaggaac agaatcttta
      721 tcttctaaaa acacagcaaa ggatactgta ttttttggag catcttcaaa ctttagaggt
      781 agtgaatatg taggcatacc accttcattg aactgagttc ctcttttacc atatttatct
      841 tctataacac catttactat acctgtacta gttactttca taataattta cctcccaata
      901 taataaatta atagaatatc tctataattc aattatatac cagttgaaaa taatggtaaa
      961 ttacttactt ttttgtgggt atctatttac tttaaaacac ctttttcctt aagaatatct
     1021 tccataccat tatccaacat aaagttaatt cctatatctt gcattatagc caaagcatcc
     1081 aatatttgtt tccctcgaat aggtgtaagt gagtattcaa ctttaagtgg gtaaccttta
     1141 tatgtctttt tatctacaag accaaattca attaattctt taagttgttc aagtaacatc
     1201 ttttgattaa taccattaat ttccttttca agttttgata aggaagttgg tcctatgcgt
     1261 aatctccata atataataga tttccatttg ccttttatca tatcatgtgt tagttctaat
     1321 gggcaagtat actcatcacg aagtttcaaa taagttcacc cccattttac tttgccaaga
     1381 tacgttttga agcaagctta tatacaaact caactttttt atttgatata tcccatgaat
     1441 ctaattcttt ttttattaaa tctggatatt ttttacttat atctctaaga gcattaccta
     1501 aagactttct caagtattcg ctatcatctt cttttaaact agagagtagt gatatagcga
     1561 catcaggatt agatttaaaa tagtctctac tagtccaaat tctaagacct tctgtcacag
     1621 ctctttttat gtttggacta tcagaattaa gccattcttt tataacagga agtgcctttt
     1681 catatcctac ttcactgcaa taataatcaa atgatttagc taatatttct tgtactctcc
     1741 agttttcgtc tttactcaca ttgtctttta aaaataacaa agcttcagaa atagttactg
     1801 atataaaacc aagtataaac acagctaatt ctcttacttg ataatattct gacctatata
     1861 agtagattga tagataataa cacttttttg agtcattatt tttcacaatt tttttagcaa
     1921 tattttcaat ttctttaaag ccattttcta tagtaataat ttttgcaatt acttcttcca
     1981 attttatctc ctccaataag tagattagtt taaattttat gtatttattt gtaaaaaggt
     2041 ttgtttaatt tagacaaaat aaagacttgt caaaaaacgt ttgcaagtct ttagtactag
     2101 cataaataaa aaataataaa aaatcaacct catttaacat ataaatttac ttttattata
     2161 agttttatat tataaagttg tatttaaaaa attaattgag ttatataaat tttacatgat
     2221 ttgagtatac taatagaata aattattata tagtaatact tatatgagat gaatatttta
     2281 ccaatcttat ttgatagtgt ataattaggt gataaagagt aacttaagca attatgataa
     2341 agaataattt aagtaattat aatgatattt acaaataatt tataatttac aaatcatcat
     2401 aatttgtttg aaattagtat gataaagctt acattaaatc aaaaatataa atatgtaatt
     2461 ttaacttgta acaataataa aaaatataga aagctatgtg ataagtaaaa catgttttgt
     2521 ctgaaaaata taaaagacaa tctaaataat aatataatga aaagtaaaat aggagggaaa
     2581 aatgatacca ggacttaaag aaagtttgct aggattaata aatgaaagtg catataatcc
     2641 tctaaaaaaa gaagaattag cagaaatatt tgatatacat tcatcagaaa tgccaatgtt
     2701 ttataatttt ttaaatgaat tagaagaaga tggttatatc tgctttacta aaaaaggaaa
     2761 aataatatct ccaaatcaaa tgggatactt tgttggaaaa tttgtatcgc acaaaaaagg
     2821 ttttggattt gtagaatctg atgttgaata cacacaggat ttatttattt caagtgacaa
     2881 tataaatggt gctatgcata acgatagagt tatggcagaa atagtagtac ctgcaactga
     2941 agaaaagaga gctgaaggaa gaatagtaaa agtaataaag agagaaataa ctagaatagt
     3001 aggtactttc caatcaagta aaacttttgg atttgtaaca ccagacaaca agaaatttac
     3061 taaggacata tatatcccta aaaaacattt tagtggagca gtagataatg ataaagtagt
     3121 atgtgaaatt acagtatggc cacaagagga tagaaaacca gaaggtaaaa ttatagagat
     3181 actaggtcaa aaaggtgaaa gaggcgtaga aatagattct ataataagag aacatggtct
     3241 tccagaagaa tttccaaaga aagtattgca agaagcagaa gctgtagctg ttgagattcc
     3301 tcaagaagag ataaaaagaa gaagagattt aagagattta aatatattta ctatagatgg
     3361 agatgacgca aaagacttag atgatgctat atcaatagaa gtattatcta atggaaactt
     3421 caaactagga gttcacatag ctgacgttac acactatgta agagagaaaa ataaacttga
     3481 caaagaagct ttaaaaagag ctacatcagt ttatttagta gataaagtaa tcccaatgtt
     3541 gccaaagact ctttcaaatg gagtatgtag tttaaatcca tttgaagata agttgaccct
     3601 ttctatattt atggaaatag accataaagg aaatgtggtt aaacatgaaa tatgtgaatc
     3661 tgtaataaat tcaaaagcta gaatgaccta tacagaagta tctgatatat tagagaaaga
     3721 tgatgaaaaa cttaaaaaga cttttgaaca tgttgttgaa gattttaaaa atgctgaagt
     3781 tttagctagg attcttatgt caagaaggga aaagagaggg gctatagact ttaatttccc
     3841 tgaggcaaag ataattttaa atggaaaagg tgaagttgta gatataaaac catatgaaag
     3901 aagaatatct aataagataa tagaagaatt tatgcttata agtaatgaga caattgctga
     3961 acatttttat tggatgggaa taccatttgt gtatagaata catgagacac catctttgga
     4021 aaaaatggaa gaattgagta agtttatatc tacatttgga tatataataa aaggtgataa
     4081 agaggaagta catccaaaag cattacaagg tataatagag aaaataaagg gcaaaaaaga
     4141 agaaggagct atcagtacta taatgcttcg ttctttaaaa caagctaagt actcaccaga
     4201 atgtagtggg cactttggat tagcagctaa attctactgt cactttactt caccaataag
     4261 aagatatcct gaccttcaaa ttcatagaat aataaaagaa tctttaaata ataaaataag
     4321 cggaaaaaga caagaacagc ttactactat agtggattat gcatctgttc aatcgtctga
     4381 gaaagaaaga aaggcagagt tagctgaaag ggatgtacat gatttctata aggctcttta
     4441 tatgaaggat aaagttggtc aagaatttga gggtgttgta tctagtgtaa cttcatttgg
     4501 aatatttgtt gagttagata atactataga aggcttgata agacttgcaa atatgaatga
     4561 tgattactat gtttatgatg agagttctta tagtgtttta ggagaaagaa ctaagaagtc
     4621 atataagata ggtgaccttg ttaagataaa ggttgagagt gtgaatgtag attttaagga
     4681 aattgacttt gagatagttg aaaagataga ggagtagata aaacagctaa aataagagat
     4741 aacaaattgt ggtgtttgtg atatggataa atatatagtg cacaatactc gataaaataa
     4801 attataaaaa caggtaatta agaaatgttt acatggaagt agccaactga aagataagaa
     4861 attaagaggt atttaataga aatagataaa tgagaaataa gaaactaaga agcatttagt
     4921 agaaatagct agctgaaaaa taagaaatta agaagcattt aatagaaata gctaactgag
     4981 aaataagaaa ttaagaaata tttaatagaa atggctaact gaaaaataag aaattaagaa
     5041 gcatttagta gaaatagcta gctgaaaaat aagaaattaa gaagcattta atagaaatgt
     5101 ataactgaaa aataagcaac taagaaacat ttagtagaaa tagctagctg aaaaataaga
     5161 aattaagaag catttaatag aaatgtataa ctgaaaaata agcaactaag aaacatttaa
     5221 tagaaataga taaatgaaaa gcaagtaatt aagaactatt taatggaaac agataattta
     5281 aaattaccta attaagaata gatataaaaa aatatatttt cgataaaaaa taagtgtatc
     5341 atttaaaatt taagatacac ttatttttta tttaagagaa cttttccttt tatataattt
     5401 ataacaagag gtttaatata tttataatta atttcaaaat tattcatatc tgccaaatta
     5461 aattcttaca tatataatta ttggtatgct tattaacact tcagaaatca ttatagttta
     5521 aattttgagt ttattgttat tacttattta atttgagcac attatttatt tttatttgca
     5581 actaataaat agagtatgat tttataatac agtttcttaa atttttttta aaagtaatag
     5641 ttcttatttg tagccaatat tgcttataga acttattgat tcatttaatt tttagaaaaa
     5701 ataataatac ttacacaata aacacagaat tttatataga taatataggt atttaaattt
     5761 aaggtgaaat gatacttttc ttaatatatt ttattgtaaa taagcttgat tataagttaa
     5821 aattaaaaaa aacactactt aggaggaatg taattatggg gatgatagga tgctatacaa
     5881 aaataagtga ggagaatgtt tttaaattac agcaagcaga agaaaattta caagatttcg
     5941 tttttgaaga ttccaacgaa aatagtacta ttaatattga taaagcatgg catgccattc
     6001 actttacttt gacaggttgt ccttttggtg gagatgaaga taatatattt agcaaactag
     6061 tgctgagtgg aaatatactt atggaaattg atggagaatt tcctgtcatg ttaattacag
     6121 ctaatgatgt aaaaaaacta tcaaaagcaa tgaatagttt ggaagaacaa gagtttagaa
     6181 aaagatttaa tattaatgag atgttagaaa acaatattta tcctgttatg aatgatgaga
     6241 gtgaagatga tttttttgaa tatgtatggg caaatctaat tgagcttaaa aggtttatac
     6301 aagaagcatc tgatgatgga caagctgtaa tattttttat aatgtgataa tcactaaaaa
     6361 attgtgaata ttagtgtcat cacatatctt agatatgaag accatagaaa aatatataaa
     6421 agaaatgatt ggtgaaagta ttagcgaaat aaattcactt tggaaaactg gtgaaagtat
     6481 aaaaataaat tattctaaag tatcttctga aagatttgaa gaaataattc aaagagtaac
     6541 accttaggag gagtgtctac atattttttg acaagttaca aatatttgga gcagtttcag
     6601 ctacctataa tgaatctatg atgatatagt atcctcaaaa tcattatctc aagttattgt
     6661 acaattaatt aggatactaa tgtcaattat aagtatagcg gtattaatca taggttttgt
     6721 aaatatttta atatatcttg gaggcgattt tttagtagtt gagtatattt ggaaatttcg
     6781 cattggctat gtctatagga agtttaggaa tgtttttctc aaatttattt aataatacaa
     6841 tcataggtta tatggtatct atgggatatt taattttaaa tatgatgact aaaggcaagt
     6901 atgttggaaa tttttttata atgtctatga gtcaaagtag ttttgatgag aaatattagt
     6961 tgatacttgg aagtattgtg ttgataattg aatctatctt aataaaacca ataaaaagga
     7021 agattagata ataaaatgag gcttagataa aataaaggta atacaaacaa aaagtacatt
     7081 tatgaaatat gaatttattt ttacatacac aaacctactt ataatctctt tatgcatgta
     7141 gatagattta tatatcagta gtataaaata catatgtata ccgaatttta tcaaaagttc
     7201 ccaaatttat atttcaaaga ccccaaagac acttattgct atgacctacg tacatgtatt
     7261 ttttcatttt aatttttata ttagcaatat gactagtgtc gtaaactatt gatacctcat
     7321 aacaaaaaat tctccatccc ctaaatatgt tttctgtctc ttagtctcaa ctattttaaa
     7381 tccttgagac tcataacatt ttacagctct catgttccag gttcttacat ttaatacaat
     7441 tggtttagta ctatatttat ttctacattc ttgtaatcct aggctaatta tttctttacc
     7501 aattcccatt ccgcaatact ctggttttat accaatacca aagaatacag agcttccttc
     7561 atctaataag tttataaaac ctatcaattc tttattgtcg tttataaaac ttataaaatt
     7621 ttttcttcta tcttcttttg ctagtgaaaa attcttcttt ttaatttcct cccatggagg
     7681 tagattgtat attgaatatt taccttcata tttccaatta ataacttcaa tagcatgttc
     7741 ttcagtaaat ttaactttat ttaaattcat atgtcctcct attaaaatat ttaaggtaat
     7801 taatggtatt ttaaaatttt agaaaataag taaaactatt tatatttatc catgaaatct
     7861 ttaaaaattt tactaacaat tcttgtaccc tgtatttttt attggattca cagaagacta
     7921 taaactaatt ttgaattacc ttctaattca aaaacctcac aatatatgta acttcttagc
     7981 ttgattaaat tctgttaaat ctgtttctta tagatttctt atagttgtat aatcaacatc
     8041 aatatattta tgtgtattag ttaatttatt gactttagga acttattatt aatatgttat
     8101 atttgcttca atactccaat agtagggtaa attgtaggca aattatcaaa tgtatatcta
     8161 tccatgctta aactttagag atacaataac tactaaatta gtattctagt agttataaaa
     8221 aagaatcttt aaaaatatta atttaactta tattttttaa taaattttct aaaatttaat
     8281 cagttaattt aattatagct ctaaatgata ttttctacag atagaatttc aaaaagatgt
     8341 gtataagaac aagttcactt aaatttttaa aatcaaataa agttgaatct cttgattacc
     8401 ttgattattt tatgaactta atatagatgt aaactttact attaaaaaaa tacgagattt
     8461 tagataagtt aatgctaatt taaataataa gataagaaat ataatatgac ataagagcta
     8521 ggaataagat aaatataatc aaagaataag gcatgagaat aattaccaag agaaatcgtt
     8581 actttaatat gtttatgaat gttagactat gttcctaaat tgaattttat atatcaaata
     8641 taataactta cagaatgtgg aaatttttat ttaaagaata cacataaaca tttccacact
     8701 ctgattttat aataataatc taataaaatt tatagtgact ttataaactc aataatgatt
     8761 taataaatat ttataaaaca actatttttg cttagaaact ttattattca tattatcatt
     8821 agtaggcatt gttccaaaac ttagtttttc atacattact tgagttggag ctagccaaac
     8881 tgtaccatta ccagtaaatg tatttaagaa accttcacca tttaaagcag aaccaattaa
     8941 agatttatct gactttgtaa cagaaaaatt aacaccagat gttcttgcta ttgcaaagtt
     9001 accatctacc tttaattctt caccattttt caattcatac tctacaattt cactttgagg
     9061 aacaacacat tccagaacga ttacaccagt accacttaat tctatttgga agaagccttc
     9121 accaccaagt aaagcagatg agaagttctt ttgtgtaaat gcttttactt ctattgtatc
     9181 agagcaacaa tagaataatc ctttatcaac aattatggaa tcattgtcaa gactcataaa
     9241 taaatagtgc ctaaaagaag gttccaaata aacttctcca gtacccttgt atacaggttt
     9301 catcattgat tcattagtaa gtgctcctga tattcctttt ttgaaaagac ctccaacacc
     9361 accaatctta gtttcagaag atatatttcc tttataatag tataatgcac cagcttctgt
     9421 ttttattgat gaattattta attttatctt aatttgtcta gctttcaaac cagcttctct
     9481 agcaaaatat aatcccattg ccatcattgg gctagaagct ccctcaagtt tttcaaattc
     9541 taatatctca aattcgcttt tgccatctga tgcattttct aaaattttta cttttttgct
     9601 taaatccata caaatttctc ccgactatgt taagatttat ctctaaaata ttataagata
     9661 taattatata ttacattttt tttgaaaaaa tggctacttt atcatcaaat ttttaaatat
     9721 ttttaataag tttttgaaat gtttagattt aagttaaatt gtttaagaac atatacttgt
     9781 ttcaataggt attttgagta ttatttattg cttttgggta ttatatttta tgggtatgtt
     9841 aaaattat
//
LOCUS       DBGJFK010000104         9470 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.109, whole genome shotgun sequence.
ACCESSION   DBGJFK010000104 DBGJFK010000000
VERSION     DBGJFK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9470
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.109"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(127..765)
                     /locus_tag="ACOIAP_003350"
     CDS             complement(127..765)
                     /locus_tag="ACOIAP_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGZ2640225.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELIEMMAVSIKYKNYSSYLKLSNEFHDIYITKSNNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKFMRENDLENIERVLREHWKTIPIAEMK"
     gene            complement(1011..2876)
                     /locus_tag="ACOIAP_003351"
     CDS             complement(1011..2876)
                     /locus_tag="ACOIAP_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGZ2640226.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELNICVKVNEGYNVKSIFL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDIPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELINKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDK
                     DSVINKWINMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFKSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYKDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRILILVN
                     RSENVESISLCMDSSFIEEIPIKYSLKNVNSTIQIENNELKVDLESKSFRIFRVN"
     gene            complement(2881..5301)
                     /locus_tag="ACOIAP_003352"
     CDS             complement(2881..5301)
                     /locus_tag="ACOIAP_003352"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HGZ2640227.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLDIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFINGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRVKRMSIIDYDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKRDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNIDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5315..6757)
                     /gene="glgA"
                     /locus_tag="ACOIAP_003353"
     CDS             complement(5315..6757)
                     /gene="glgA"
                     /locus_tag="ACOIAP_003353"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGZ2640228.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTNAVLESISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQTYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDASIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6786..7916)
                     /gene="glgD"
                     /locus_tag="ACOIAP_003354"
     CDS             complement(6786..7916)
                     /gene="glgD"
                     /locus_tag="ACOIAP_003354"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGZ2640229.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7918..9078)
                     /locus_tag="ACOIAP_003355"
     CDS             complement(7918..9078)
                     /locus_tag="ACOIAP_003355"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGZ2640230.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         2993 a         1742 c          921 g         3814 t
ORIGIN      
        1 tattgtagtg tcttagagct tttatttgta ttttaaatta aatttattct tgtttttcct
       61 ttaataatta atagtaaaac aaaaaaaata taaaaaaaat aaagagaaac tttataaaag
      121 cttctcttat ttcatctctg ctataggtat cgttttccaa tgttctctca aaactctttc
      181 aatattttct aagtcattct ctctcataaa ttttactact tcaatatgtt gattattgct
      241 gtatgtcaac attttatata actcatcttc attatcacta gtatatgact ttgacataaa
      301 attgtatctt aaagagttca atagatttac taacacctga ttatttgatt tagttatgta
      361 tatatcgtga aattcattgc ttaattttaa atagctactg taatttttat actttataga
      421 gaccgccatc atttctatta attcttccat tttcactagg tctgattcag ttaaattttg
      481 taatgctgaa gaaccggcta acgcatccaa tactccaatt acagaatagg tgtctaattt
      541 ctccttttct tgaaattctt ttactacaaa tcccttatta ggtatttttt ctagtaaatt
      601 ttcacctgct aacctagtta atgcttctct cgctggtgtt ctactaactc cgatagattt
      661 acaaatctca gattcagtaa ttctctgatt agcttcatac tctccatttt ggattttctt
      721 tgatatatag tcatatactt gagttgtaag tggatctacc ttcataagac gttcctccat
      781 attaagatta taaaagttaa atctccctac aactttggta gagagttcag ttttatctta
      841 ctaatttata taatatcaca attatgatat tttttatact tctttgtaat attttgaaat
      901 actaaaattc ttatgataat ttatacaaaa aaatgtagaa aaagttttga taaaacaaaa
      961 ctctttccac attcccctta ttttctattt atttttctaa acaaatatat ttaatttact
     1021 ctaaaaattc taaatgattt agactctaaa tccactttca actcattatt ttcaatttgt
     1081 atagtactat ttacattttt aagactatac tttataggta tttcctcaat aaaactacta
     1141 tccatacata atgatatact ttccacattt tcacttctat ttactaaaat taatattcta
     1201 tcattatttt cattaactct aataaaggaa aatacagaat cattattagt atatataaat
     1261 tctgtatttc cagaacttaa aagtttattc ttatttctaa tttttataac atctttataa
     1321 aaattaagca tatcttcatc ttcatttttc catggatatg ttcttctatt atctgggtca
     1381 acacctccac aaagacctgc ttcatctcca tagtatatat atggtactcc ttcaaatgtc
     1441 atctgtatag ctacagcaag cttcactaaa tctacatcat catttaattc tgttttagct
     1501 cttgtaacat catgtgttcc aattaaattt aaattagact taaatgattc ctttggataa
     1561 ttttctttaa tctgcatata tctattacaa agttcgtatg aattaatttc tccttttaag
     1621 aaagaaaaca tgttatttct aaaaggataa cccataacag aatctaattc ttcacctaat
     1681 aaataacttc ttctctgacc atagctaatc ttatttgatg catcttccca tacttcacct
     1741 ataagaattg agtcatcatc cgcctttttt aattcctttt ttagttctct tataaactta
     1801 gttggtagtt cgtctgcaac atctagtctc cagcccttaa tacccatatt tatccattta
     1861 tttataacgc tatccttatc atatattata taatccatgt agctatgttc taattcattt
     1921 atatttggca atgtcttaac atcccaccaa cttttatact tttggggaaa ttcttcaaac
     1981 atataccatg aataatatgg agattctttt gattgatatg ctcctaaact attatagttt
     2041 ccatacatat taaaatattt actatctgct ccagtatgac taaaaactcc atctaatact
     2101 attgatatac ctttttcttt tgctttatta ataagttctt taaatgtatc ttcatcccca
     2161 aacattgggt caattttttt ataatcacct gtgtcatact tatgattact agaagcttca
     2221 aatatagggc ttagatatag tatacttaca cctaattttt ttaaatatcc aagtttattg
     2281 attatccctc ttaaatttcc accatggaaa tcccacctta taacatcccc ttgactatcc
     2341 tttatgtaca taggtatatc ttcccaattt ccatatatga aactattttt tttaggatta
     2401 tcaaccttac cactacgatt cccattatta aatctatcta caaatatatg ataaagtatt
     2461 ccttctttgt accacgttgg tactttaaaa tctttgtaaa cagtgatttg atatttatta
     2521 atatcactat aattatattc acaagagtat ccgttatctc tgttttttcc ataaaataaa
     2581 gtctttatct gaccatccat ttcaacatca actttaaagt aataaaaata aacacctgtc
     2641 ccatcaaact tttcaatctt accacaaaag cactttccaa gtttatcatt atctaattct
     2701 tcatttaaag ttattgttct catttcttct tctctattta tttctaggaa aatagacttg
     2761 acattgtatc cctcatttac tttaacacaa atgttcaatt cctcatcaaa ttttaaagct
     2821 ccaaacggag ccttaaaatt tttatcccaa gaattatatt ctattacact ttgcatttaa
     2881 tcacaccctt ttaaaccaaa tgtcttttgc atactcagaa attgttctat cagaagaaaa
     2941 aaatccagag ttagctatgt taactaaaga cattttattc catttttctt tatctctata
     3001 taacctgttt atatctgctt gagcttgacc ataattttca aaatctctca atacaaaata
     3061 ctcatcattg taagtagtga gtgagttata aatacttctt ccttcttcgc caagattagg
     3121 aataaatcca tttattaaat catctactac cctttttata tccatattag aatgatatag
     3181 gtcaagtgaa gaatatccac catatttatt ataatttagt acttgttctg cactaagtcc
     3241 aaataaaaac atattttctt taccaacctg ttcacatatc tctacatttg caccatcaag
     3301 tgtagccaaa gttatagcac cattcatcat aaacttcata ttacttgttc cagatgcttc
     3361 ctttgttgta gttgaaattt gctcactaac atttgctgct ggtattatta tttctgctaa
     3421 tgatactcca taattctcta aaaatactac ttttaacttg tcctttactc taacatcatt
     3481 atttatagta cttgcaacag aatttataaa tttaattata catttagcca aataatatcc
     3541 tggtgctgct tttgcaccaa atataaaagt tcttgggtca agatttaaat taggattatc
     3601 aagcaattca tgatacatat gaagtacatt aaatatattc agtaactgtc ttttatatgc
     3661 atgcaatctc ttaacttgaa catcaaatat tgaacttggg tctatattta aatcgtattt
     3721 atcttttata aactttgcta gatttgcttt attattgtat tttatatcat caagtctttg
     3781 taagacagaa gaatcatttt taaatttttc aatatttttt aattgtaagg tatccctctt
     3841 ccatgaatca ccaattaaat ctgtaattaa attgctaagt tgaggatttg aacttataag
     3901 ccatcgtcta tgtgcaattc cattagtctt attattaaat ttatttggtt catcttggta
     3961 gaaatctttt aatacctctg tttcaagaat atgagtatga agcttagcaa ctccatttac
     4021 actatgactt gtcacaatac ataaatttgc catattgata ttgtcatagt ctattatact
     4081 cattcttttt actctatctt ggtcatatcc tttattattt aattcctcta catatcttct
     4141 atttatttct tctattatca tataaattct tggtaatagt tctttcatca tacttacagg
     4201 ccatttttcc attgcttctg acattatagt atgattagta taagacactg tttttttagt
     4261 tatttcccat gcttcatccc aagataaatt ttcttcatca agcaaaattc tcataagttc
     4321 tggtatgcat aaggtaggat gtgtatcatt tatatgaatt gctaccttat cgaataaatt
     4381 attgatattt aatttgttct ttttatattt tcttattata tcttgtatcc ctgcacttac
     4441 aaaaaagtat tcttgtttca acctcaacaa cttacctgca taatttgaat catcaggata
     4501 taacacctgt gatatttcct cagtatagta cttatgtttt aaagcctctt catagctacc
     4561 agagtaattt agagcatttg aggtaagctc accaaaatct ctctttggta tttcactctt
     4621 aaacaatctt aaagtattta tacattggtt ttggtatccg attattggta tatcataagg
     4681 cattgccatt acaggaaggt agtttttatg aattactttt aaatgactac cttccttgat
     4741 taattctacc tcaccaccaa acttcaccat tgttgcttca tttggtctta cagtttccca
     4801 tgcatatcgt ccttctgtaa gccagttatc aggcacttct acctgataac catttataaa
     4861 tttttgttca aacagaccgt atttatatct tattccatat ccttgaccac ttatgttcaa
     4921 agacgccata gaatctaaaa agcaagctgc taatctacca agcccaccat ttcctaaggc
     4981 tgggtctact tcagcttcta ttaaatcatc caagttgatt cctaactctg acaaaccttc
     5041 tctaacttct tcttcaatat ctaaatttaa taaattagat tttaattgtc tccctattaa
     5101 aaattctaaa ctaaaataat aaacctcttt tttcttgtct aactttgtag caacccattt
     5161 ttttgctatt tcatctttca atagactaca taatacattt aacaattgtt catcagtagc
     5221 ttccttgata gattgtgcat ataagctata catttttact tcaaattttt gcttgaattt
     5281 ctttttgctt attgttacca aaaaaaccac tcctttaatc acatatgtct ctatatgttt
     5341 ctatatactc cttagctgat tttttccaac tattatctgt tttcattgca ttttcaacta
     5401 atttaatcca tttttctttg tccttaaaca ctttgattgc atttttcaaa cagaaaaaca
     5461 tctcatgagc attgtaattt ttaaaactaa atccattgcc ttctccagta aatttattat
     5521 aaggtgttac tgtatcccta agccctccag tctccctaac tattggtaaa gaaccatatc
     5581 tcatagctaa catttgacct ataccacaag gctcaaataa tgatggcatt aagaacatat
     5641 cacttgcagc atatatctgt tgagccaatg atgcattgaa agtaattcta gctgatactt
     5701 tatctgaaaa attagaatcg taatagttga acattgattg atattgatgt tctccagttc
     5761 ctaaaacgac aatctgtaaa tcttctctca taagttctgg catcatgtat gctattaaat
     5821 caaatccttt ttgagaaact aatctcgaaa ctatacctat caacggaata gatgcatctt
     5881 ttttaagtcc caatatatct tgtaatctca atttattttc tacttttttg tcaattgagt
     5941 ctacatcata atgaacaaat atatctttat cttttgcagg gtcatttaag tcataatcta
     6001 taccatttaa tatacctttt aattttcctg actcttttct aagtaatcca tctaattgtt
     6061 caccataaaa agatgtttgt atttcatttg cataagtagg actaacagtt ataattttat
     6121 ctgcaaaatt tataccagct ttcataaaat ttattgagcc ataatactct atatctccat
     6181 tatcaaagta tgtttgtggt aagtccaata tatcatataa aacatgctta tcaaatacac
     6241 cttgatattg gagattatgt atagtataca tagtttttat atttttatac ccctcaaggg
     6301 ttgcatatct ttcttttaga attaatggta acatccctgt atgccaatca tttatatgta
     6361 ttacatctgg ataaaaatca attctactta tagattctaa aactgcattt gtaaagaaag
     6421 tatatctttc tgcatcatct ccatatccat agatgctctt tctttcatct tctcttctaa
     6481 aataaaactc attatctata aagtaaaatt ttacaccatc aagttccatt tccaaaagac
     6541 cacagtattg atttctccat ccaacacgta cactaaacac agctatttct tttagttgat
     6601 cttttaaata acttggtata gttgaatatt tgggcattat tacccttaca tctacacctt
     6661 ctttttttaa ttctttaggc aatgcataag aaacatctcc taatcctcca gtttttgcaa
     6721 agggccaaca ctctgctgtt acataaaaaa ctttcattag tcattccccc ttctaaaaaa
     6781 tttatttata tatttgtatt cttttccact acaagaggat atttttcatc tcctcttaat
     6841 tctttcccat ttgatacact cgtattttta tctaatattg cattatataa ttttgcattt
     6901 gactttatta cacaattttg cattactatt gagttctcta taactgttcc tttttcaaca
     6961 tttacctttc taaatatgat actatctttt acagtccctt caattaaaca accagatgct
     7021 ataaagctgt tttctacttt agcactatct gtataaattg taggtgattc attcttttct
     7081 tttgtaaata tctttctttc agaatataat aattcatcag caacttctaa atttaataaa
     7141 tctttgctca tttcaaaata tgattcaaca gaatttacac attttagata tcctgtatat
     7201 tcataagctc ctattttcat gttttctgct tcttcaataa taaattcttc taaataacaa
     7261 taattgcctt tatttacaat gttatatata cattcaacaa aatcttcacg tttcataata
     7321 tacgtttcca tacatatatt tgctctaggg aatttaccca aattatttcc tacatttatc
     7381 actctattgt tactatctaa atttagagtt aagttaccag caaaatcttt atttgcatta
     7441 tttacatttt tatatattat agttatatca ttatgagatt ttttgtggta ttccaatgct
     7501 tgagaataat ttaaattaca tagcatatag cttggagcta ttaaaatata ttcttcttca
     7561 ctcttttcta tataatctag attagctaag atagtatata tatcaccttc tctatgtgag
     7621 taagtatttc tatacttagt gttttctgga ctaaaaattg ataggccacc tttctttcta
     7681 cttaaatccc aatctttacc actacctata tggtctgtca atgatctgta tttttccttt
     7741 gcgaatattc caaccttagt gattcctgaa tttatcatat tagataaagc gaagtctatt
     7801 attctatatc ttccagctat tggtgtagat gctattggtc ttccatagtt aagtttgttt
     7861 attgctgggt ctcctttttt gtttaaattt attatcccta aacattcatt tctcatctta
     7921 aagacctcct tctattaata cgcatctagg ttctatattt tcatactcag aaactacatt
     7981 tatttcatta tttacattct ttatctgaac attatcattt atagttgcac actcacctat
     8041 catagctttt tctatagtta cattttcacc tattacaaca tttggcatta ttactgagtc
     8101 aattacttta cttcctttac caacaacaac tccatgtgat agtacagaat tacctacttc
     8161 acctaaaatt ctacaaccat cagctatcat tgatctatga acatttgcat ttttacctat
     8221 atattgtgga ggcattgcca tagtatttgt atatatcttc catttagggt ctgctaaatc
     8281 aagtgtttct ggagatttta ttatatccat attagcatcc cataagcttt gtatagttcc
     8341 tacatctctc cagtatcctt taaatggata ggcatacatt ccaacattat cttctaacat
     8401 tttaggtatt aaattttttc caaaatcatc ataatttatt tccggatttt tttctgcttc
     8461 cttaaaataa tttctcaaca ttttccaatc aaatatgtat actcccatag atgccaaatt
     8521 actcttaggt tcacttggtt tttcttcaaa ttcatagata cttgaatctt catttgtatt
     8581 cattatccca aatcttgaag cttcatccca aggaacttca attactgcta ttgtagcttt
     8641 agatcctttt tccttatgaa attttaacat tttactataa tccatcttat atatgtggtc
     8701 accagataat atcaatacat attctggatt ataggtatct acaaagtcca tattttgata
     8761 tatcgcatgt gctgtaccat tataccaatt tccttctttt tcattcataa atggttgtaa
     8821 aacatagacc ccaccattta ttctgtctaa atcccaatga cttcccatac ctatatgtga
     8881 atttaatatc aacggtctat attgagttaa aacacctaca gtatcaatac cagagtttga
     8941 acaattactt agcacaaaat ctataattct atacttacct ccaaatgata cagctggttt
     9001 agcaattctt tttgtaaaga cgcctaatct tgaaccttgc cctcctgcca aaatcatagc
     9061 taacatctct tttttcattt aatgacactc ccctcatcta gtaattagta tttataattg
     9121 catttttact tttataaact ttatcagtca ataaatgttg tgtataaatg ttgcttaaat
     9181 aataccttaa taaaaataaa ataatatcaa ctatacaatt gatacaatgt ataccccata
     9241 atgcacttgc cgacgtatac attattttcc ataatcacta tagtattaat taatattcaa
     9301 ttatcagtta aaaaataata caaattttat tttataaata taaaaacatt ttttataaat
     9361 ctcttgtgcc atacaaacat acttgttttt taatttgtta aattcataat agcaaaatac
     9421 aatctaacac ttgttaaata attatccaaa taaaatcaag taattattaa
//
LOCUS       DBGJFK010000105         9390 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.110, whole genome shotgun sequence.
ACCESSION   DBGJFK010000105 DBGJFK010000000
VERSION     DBGJFK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9390
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.110"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            358..1563
                     /locus_tag="ACOIAP_003356"
     CDS             358..1563
                     /locus_tag="ACOIAP_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2640231.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTDHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     TVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLISRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1634..1855)
                     /locus_tag="ACOIAP_003357"
     CDS             complement(1634..1855)
                     /locus_tag="ACOIAP_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640232.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(1997..2596)
                     /gene="recR"
                     /locus_tag="ACOIAP_003358"
     CDS             complement(1997..2596)
                     /gene="recR"
                     /locus_tag="ACOIAP_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGZ2640233.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2609..2959)
                     /locus_tag="ACOIAP_003359"
     CDS             complement(2609..2959)
                     /locus_tag="ACOIAP_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGZ2640234.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3018..4655)
                     /gene="dnaX"
                     /locus_tag="ACOIAP_003360"
     CDS             complement(3018..4655)
                     /gene="dnaX"
                     /locus_tag="ACOIAP_003360"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGZ2640235.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4732..4996)
                     /gene="ffs"
                     /locus_tag="ACOIAP_003361"
     ncRNA           complement(4732..4996)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACOIAP_003361"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5034..5125)
                     /locus_tag="ACOIAP_003362"
     tRNA            complement(5034..5125)
                     /locus_tag="ACOIAP_003362"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5089..5091),aa:Ser,seq:gga)
     gene            complement(5126..5581)
                     /locus_tag="ACOIAP_003363"
     CDS             complement(5126..5581)
                     /locus_tag="ACOIAP_003363"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HGZ2640236.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5903..7174)
                     /gene="serS"
                     /locus_tag="ACOIAP_003364"
     CDS             complement(5903..7174)
                     /gene="serS"
                     /locus_tag="ACOIAP_003364"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGZ2640237.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEKEFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKNIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYALM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIR"
     misc_binding    complement(7299..7505)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7633..8514)
                     /locus_tag="ACOIAP_003365"
     CDS             complement(7633..8514)
                     /locus_tag="ACOIAP_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGZ2640238.1"
                     /translation="MNFLSLAKSASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDLVKSILNEIFINEKR
                     ILDDPRPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENNIKVPFVP
                     SSLLFNNMSNLNTMDKR"
     gene            complement(8526..9035)
                     /locus_tag="ACOIAP_003366"
     CDS             complement(8526..9035)
                     /locus_tag="ACOIAP_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGZ2640239.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIAII
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9163..9279)
                     /gene="rrf"
                     /locus_tag="ACOIAP_003367"
     rRNA            complement(9163..9279)
                     /gene="rrf"
                     /locus_tag="ACOIAP_003367"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3010 a         1651 c         1004 g         3725 t
ORIGIN      
        1 catctttatc ctgtctagtc aatataattt tttaattttt ttatttatca tatattcttt
       61 atatttaatt tccaaaacct aatgctaaac aaatctgttt atttcataaa actaatatat
      121 attctatgct ctattttcct ttttattcta tatttaaatt ttttatttac aataatattt
      181 ttaacataac atatttgata aaattaaatt tcatttcttt cacttgtaat ttttgtaatc
      241 ttgtattaga ttaatattaa aaaatagttt atcaataacc ttatttacaa agacagtttt
      301 atatatcaaa acataataca atataaatac tatgctacat tttaggagga ttttattatg
      361 agcaaaaaag tattaataat gtctgcttcc actggtggtg gacacaatag agctgctcta
      421 gctattaaag aagaacttac ttcaaaaaca cttgatggag agccaattga atgcgaaata
      481 atagatagtt tgaaattagt taataataca atggacaaga taatttcaag aggatacgaa
      541 aaatctgcta tatatactcc caaagcctat ggaagtgtat atagattatc tgaaacaaat
      601 cttttatcaa aaaatgaatt taaagataat ctactaataa cattcatggc taaaaaattt
      661 aaaaagctta ttagaagcga aaaaccagat ttgattatag gaacgcatcc ttttccaatg
      721 attgctctta gtacattgaa aaaaaacttt aatttacata ataatgaatc aaatgcttat
      781 acagatcatt tttataaaca ttatacaaat accattaatg ttcctccgct tatttctgta
      841 ttaactgatt atactactca ctctacatgg atacaaaatg aaattgatta ctatattgtt
      901 ggtcatgaat atgtaaaaga actattggtg tttgatggag ttgaaccgag taaaattaga
      961 acatttggaa tccctgttga aaaatctttt ctctctcaca gagataaaga tactgttctt
     1021 tctgagttga atctatctcc tgataaatta actgttttac ttatgggggg gagctttggg
     1081 gctggaaata taaaagaaac tcttgatgaa ttattggata ctgatagaga ctttcaaata
     1141 cttgtaatta ctggtaagaa tgaaagccta aaagaaaaaa tcgaaaaaaa acttatatct
     1201 cgttatcatg ataaaaatgt atgtgttctt ggatatactg ataagatgaa tgatatttta
     1261 gcttctatag atgtattagt aagcaaacct ggtggactta ctacaactga ggctctttta
     1321 aaagatgtac ctatgatagt tccttattat ataccaggtc aggaagaaga aaatcttgat
     1381 ttcttatcta attgtggtgc agcgcttaga actacaaaaa aatataactt gtcaatatta
     1441 ctaaaagttt taatagatga ccctagcaga ttagaaatgc taaaaagaaa tattaaatca
     1501 ataagaaagt caaattcagc ccaaaatata gctaatttaa ttttaaatat aatttctggt
     1561 tgataaaata aataaaatcc ctatagtata tatattatct attagggatt ttttattttc
     1621 taattattta atattaaatt ggttcataaa agtcttcttc gtaatcatac tgataatttt
     1681 tataattatt tctaaattca gcatttttat ttcgtacatt ttttttagtt tttttcttat
     1741 tagaaaaact tatatcctca aaatcatcat atttaggttt atcttttgat ttcatttttt
     1801 taactctttt ttctttcatt gcattatgtt cttctaagtt cataattggt ttcatgttgc
     1861 acccctatca aaatttttaa atgatttata caacaaatta tacaatacag aagaaattta
     1921 ttcaataaat ctaaatcaaa attaatttga atttaaccca aaaaaattac aaaaatcgag
     1981 gtattaacct cgatttttat atttctcttc tgccttctag tgcttttgat attgtgacct
     2041 catctgcata ctctaaatcg cctccaacag gaagaccatg agctatccga gtgactttga
     2101 ttcccattgg ttttactaac ctagcaatat acatggctgt agcttcacct tcaatagtag
     2161 gatttgttgc cattattatt tctttgactt cctgattgcc aagtctttgg ataagttcct
     2221 ttatttttaa catatctggt ccaattccat ccattggaga aattactcca tttaatacat
     2281 gatactggcc tttaaactct ctcgttctct ccatagctgc tacatctctt ggatcttcca
     2341 caacacatat aacacttgaa tctctacttt tatttgaaca catgctacat gggtctgtat
     2401 ctgttatatt acaacaaatt gagcaatatc ttatttctct ttttgcatct ataatcgctt
     2461 tagataaagc ttccacatca ttagtattca tgttaataat atgaaaagcc aatctttgag
     2521 cagtctttct tcctactcca ggaagctttg aaaattcctc tataagtctc gttattggac
     2581 ctgtataaac ttgcataaat accacctact agaataaccc aggtatattc atacctccag
     2641 ttaccttact catttgactt gcttgtatat catcaatatt tctcaatgct tgatttactg
     2701 cacttaaaac taaatcttgt agcatttcta tatcatctgg atcaactact tctggtttga
     2761 tagttatatc tataacttct tttttaccat taacttttac agtaactgct cctccaccaa
     2821 ctgaagcttc tacttcttta ctttctaact cttgttgagc tttttgcatg ttttcttgca
     2881 ttttttgagc ctgctttaac aagttgttca tatttccacc accaggcatc attccgcctc
     2941 caaaaccttt tttagccata aacactattc ctcctaaact tattttcatt ttattattat
     3001 atcataatag tattttatta tttactctca ttttcatcaa tactatcttt tatttctaat
     3061 atctcttcac tcactatgtt ctttaatatc tcttcaccaa tgtccttttt ttctttaact
     3121 tcaagattta tatctttaac ttctgatgtc agtactattt ttacattaaa acttctattt
     3181 aaaacatctc ttattgtttt ttctaaataa tttattgtat cttgagagct cagtctagtt
     3241 tttgcaaaat caaatttatc atcaaatata acatacaaca tattagaata tacattaaaa
     3301 ctttttactt cacttaagag tgcgtatatt ggcatttttt tatctttttt aatttgttta
     3361 agtatattct tccaagatga ctctataagt ataacgtcct cattttttac atcttcataa
     3421 actacatttt cttgttttac atctatttct ctatcaacct catactcttt ttctttatta
     3481 ttcccaattt tttcagactt aaagttcccc agttcaatca ttttttctag gttctcaact
     3541 ctttttataa gagcttcttt actttcatca aacattggtt gagcaatttt cattatggtt
     3601 atttccacta aaacccttgg atttgaagat gactttatat catcctgagt tattgataat
     3661 atatttaaaa tccttattaa atcatttata tctatatttt tagattgaat tttaagttgt
     3721 tctatagttt cttctggtaa tgaaattatt tcatccaatt ctgatgaaac cttacatacc
     3781 attaaatttc taaaatgatc aattaaatca tttataagat ttcttatatc tttgccccat
     3841 aagacaaatt catttaatat ctcaagagac tttttagtgt cctgctctac aatacattga
     3901 gacaattcaa ataattgttc tatatttacg cttcccatta attcaacaac atctttataa
     3961 tctatcttac tttctccaaa agacatacat tggtctaata tactaagtgc atctctaaga
     4021 gctccttgag aatttctagc tattaaatta agagctttat catctatatc aattccttca
     4081 tcttcacaaa tctttttcat tctaagggtc atatctttaa ctgtaactct tttaaaatcg
     4141 tatctttggc atcttgataa aatggttgca ggtattttgt gaggctctgt agttgctaat
     4201 ataaaaatta catatgatgg aggttcctct aaggtcttta ataatgcatt aaaagctcct
     4261 tgagacaaca tatgaacttc atctattata tatactttat atttagcatt ggccggagaa
     4321 tatttcacac tttctctaag ctctcttata tcatctacac tgttatttga ggctgcatcg
     4381 atttctacaa catccattgt attatctttt aatacagatt cgcatatctc acactcatta
     4441 cacggttctt catttatttt attcaaacag tttactgctc tcgaaaaaat ctttgcagta
     4501 gatgttttac cagtacctct tgttccacaa aacaaataag catgtcctat attatcacta
     4561 tatatttggt tttttaaagt cttaataata tgatcttgac caataacatc ttcaaacttt
     4621 tgtggtctat atgctctata taatgcttta tgcatctttt tacctctctt tagcaaaatt
     4681 aataaaaaaa tccctcatta tctaagggat tagtctttta tatattaaat gctgtacacc
     4741 atctatcgac ttaattccat aggcgttacc aaaacagtta gctcaactta ggcaccccca
     4801 cggcacacaa aagtgatcac ttaccgctgc ttccttccgg atctgacggg gttcatgagc
     4861 tttcattgcg caggacctaa gcatcaacac cacttattta gggcggccct acagaaaata
     4921 agcctttaga tggaattcaa tcctgctata gcggattgca ggttacaggg caccgctacc
     4981 tccccatcta gtacagcaaa attacaacca tatttaatta ctttcattgt ttctggcgga
     5041 gagagtggga tttgaaccca cgatacagtt ttacccatat actcgctttc caggcgagcg
     5101 ccttcgacca ctcgaccatc tctccttaat ctctttttct caatgcctta aaaaattctt
     5161 gcaatatgat cgagcattct tcttgcaaaa catcaaaagc tacttttaca ttattattat
     5221 taaaataatc taatttaaac tcatgctgtt tctctatata tgaatttttt acatgtcttg
     5281 tccctattat aagctttttt attctagaat taactattgc accactacac attatgcaag
     5341 gttccattgt aacatataaa tcacaatcag tcaacctcca accacctaat ttttctgatg
     5401 cttgttttat cgctaaaatc tctgcatgag ctgtagagtc ttttaacgtt tctgtaaggt
     5461 tatgagctct agctattatt tgattatctt taactataat agcacctatt ggtgtttctt
     5521 ttttattata tgctttatat gcttctttta atgcttcttt catataaaat gaactttcca
     5581 taattcctcc caaaacttat aacaaactta tcttatcata attcatttta taattcaact
     5641 taattttatt ttgtttattt aattatcact atatatagct atattttttt aatattagtt
     5701 ctaaaataat ttttagatat ttatacaaga gtattttata aaaatattta gtgttttatg
     5761 atgaaaattc tgtcatataa attaacataa aaaaactatg aaatttaata tttacaacaa
     5821 tttcatagtc ttttaattta ttgtttactc ataacatctt ttcttcatta aagcatattc
     5881 tatacataca attaatataa aattatctta taacatcaac acccatataa ggtcttaatt
     5941 cttctggaac tactacagaa ccatctgcct gctgataatt ttctaatata gcagccaaac
     6001 atcttcctat cgctaatcca gaaccattca atgtatgaac atattctgct tttgattttt
     6061 tatctctttt aaatcttatt cctgctcttc ttgcttggaa atcttcaaaa tttgaacaag
     6121 aagatatttc tacatatcta ttgtaacttg gcatccaaac ttctaaatcg tatttaaatg
     6181 cagctgtaaa tcccaaatcc cctgtacata tttttacaac tctatatgga agacctaaca
     6241 tttgcaacat agtttcagca tcatgagtta atgattctaa ttcattataa gaatcttctg
     6301 gttttacaaa tttaactaat tcaactttat taaattgatg ttgtctaact aaacctcttg
     6361 tatctcttcc tgctgaacct gcttcagatc taaaacaagg agtatatgca caatatttaa
     6421 ttggaagttc tgcaacatct aatatctcat tagcatgtat attagtaaca ggtacttcag
     6481 ctgttggtat taagaaatac tctaatcctt ctatcttgaa catatcttct tcaaatttag
     6541 gaagttgacc tgtacctata aaactatttc tattagccat aaatggaggt aaaacttctg
     6601 tatatccatg tttagctgta tgagtattta aaaagaaatt cattaaagat ctttctaatc
     6661 tagcgcctaa acctctatat aaagtaaatc ttgaaccagt tatttttcca gctctttcaa
     6721 aatccaatat acctagacca gtaccaatat cccaatgtgc tttgtgttcg aaatcaaatt
     6781 tagtaggctc tccccaagtt cttatttgaa cattatcttc atctgtttca ccttgtggta
     6841 cctctggatg aggaacattt ggtattctca tcaatgcgta ttccattttt gcttctactt
     6901 cttttacttt ctcatcaata ccttttattt tatctgataa ctcttttaac cttgcctttt
     6961 cttctgttac atcctttcct tcttttatta attgtggtat atttttagaa tttacattta
     7021 attcattttt cataacctca acttcttgaa gtatctctct tcttttatta tctaattcaa
     7081 ccacagcatc aaggtcaaat tctttttcgc ctcttctttc catagctttc ttgatatcat
     7141 ctaaattttc tcttattctt ttaatatcta acatattaat tcctcctaat aattttgata
     7201 atataaatta taattccaat taatttacaa ttattctagt tgtaaacctt taatttaaac
     7261 aaatttgaaa aataaaaaaa gacctccgtt taccctataa aagggacgaa aatcttttat
     7321 ccgcgttgcc accctaattg attatactaa aatgtataat cctctcagac ctataacgta
     7381 ggtaaaccgt ctagctttaa ctagaagctc tagagtagat tcaaaaacca ttgtaatgag
     7441 ttctcaccat ccactcattc tctgaataca atctgttttt tactattttc cttcacagct
     7501 ttttaactaa ttgttttatt tgataatcat tatattatat atattaacat ctttcaatac
     7561 tattattcaa atttttttag aattttcttt aattttttat attaaattca ctttttttac
     7621 ttaattaaaa ttctatcttt tatccattgt atttaaattg ctcatattat taaataataa
     7681 tgaggaagga acaaatggaa cttttatatt attctcatca aatttatttt tgactttttc
     7741 cattacatca aaataaacat cccagtaatc atcagtttta acccatggtc tagcaactat
     7801 ttgcatggta ttatttccta tagagtttaa acctataatt ggtcttgggt catccaatat
     7861 ccttttttca tttataaaaa tttcattcaa tatagactta actaaatcga tatcactatc
     7921 atatgaaata ttatatgaaa aatctatcct tcttttattt tgatgtgtgt aattaattat
     7981 attgttactt gtcaattgaa agtttggtat aattatggtt ttattatctg gagtcttaag
     8041 aacagtacta aatatttgta tgtcagaaac tgtaccttct acacctgaac cttgaatata
     8101 atcacctata ttaaatggct taaaaaacaa aataatcatg cccgaaccta aatttgataa
     8161 tatttcttta aatgctaaac ctatactaaa tccagcagct cctaacacag ctacaactga
     8221 tgtagtttgt attcctataa tccctaaact tatcaatgat ataatagata acatagatat
     8281 atatattcca tatacaatga aattatttac acctttactc attccatatt tgattagaaa
     8341 ctttgaaacc atccttctta ctattttaga tatataaata cctatcacaa atacaattat
     8401 tgcatatata atatttggta tattatcact aaaattatcg agcatatttt ctaaagttct
     8461 cttagttatg ttactatttg ttgaggcaga cttagctaat gataaaaaat tcatttaact
     8521 cctccttacg ataagattcc gttgtccttt aactctttta ctatagcttc tatagtttcc
     8581 tcttttattg cctcaattgt atgaatatgg ctacattctg tcagaaccga taattgttta
     8641 aattcattag tctcaacttt cttcataaag ttgtctatat ccattttaga ataaatatta
     8701 agttctgctg ttatctgacc atatgttgga tgatttacga tgacatcttt tataatacca
     8761 cctaaatcta caattatctt taattcatca taaatttctt tagaatcttt atggttttta
     8821 cattttattt gttttgtaaa atacggttga ttatatatta tatatccttg aggtgtagct
     8881 attatttcaa atcctctagc tcttataatg gctatatctt gtactattac ttgtctactt
     8941 acatttaata gttcagctag tgttccacct tttacaggat gcttagattc tttcaaaata
     9001 tctattaatt tacttcttct ttcattagaa ttcatattac accttctttc caaatcaaaa
     9061 actttaccta tattatataa ttctatattt tatcttatta taaatcaata ttgactttat
     9121 attctattta atcttaattt ttataataaa tgaaaaaaga ctacgtggct acgtcctact
     9181 ctcccaggca gtttcccacc aagtaccatc agcgctagag agcttaactt ctgtgttcgg
     9241 aatgggaaca ggtgtatcct ctctgctatt gtaaccacat aatctttatg cttaatattt
     9301 ctattaagtt tttaataatt ttttagaatc tagtaatact agttctttta gagttaacac
     9361 tctaaaaact acacatatat cttagtaagt
//
LOCUS       DBGJFK010000106         9283 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.111, whole genome shotgun sequence.
ACCESSION   DBGJFK010000106 DBGJFK010000000
VERSION     DBGJFK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9283
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.111"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..221
                     /locus_tag="ACOIAP_003368"
     CDS             <1..221
                     /locus_tag="ACOIAP_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640240.1"
                     /translation="INKFYILLITLLIIVGLYFSTIYISIITLFRKYYMAIGFQFNNL
                     VAGLLSFLIIMFILNGISYLLIKKKISL"
     gene            232..1431
                     /locus_tag="ACOIAP_003369"
     CDS             232..1431
                     /locus_tag="ACOIAP_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640241.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDPNELD
                     YININFGYAFNGYVNSYYTINGSNKTKKTELIKLQKDAKNTNNLIDVSSGSDLIAHVG
                     FEMNDDSKDINFVIDEKKEDLEKGVFPSEGDDKAVEYEKLDMNDFTRTRYKVDKSSDN
                     YYANILSSKRYKKYLYVSVLYATSDSSKNNKEYSSTIDIIKINPENKKIQTIKSINLS
                     NYFSKKYQNIDNISVSYASKYEDKMYILVNVLNANTGDKSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKVKLEDNKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYILDN
                     KEKRGIRSIEIDSNKIIVYTSRLNSTLSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            1440..2252
                     /locus_tag="ACOIAP_003370"
     CDS             1440..2252
                     /locus_tag="ACOIAP_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640242.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNAIGFSSFRNIMGYTESWFMFGIIVCICYAFFIWYRDF
                     NGRSKSIYTLIMIPKNRINIYISKLLNILFLVYSYTVVLTISLFITSKLLPRHMLGNV
                     TSYGFVQETIYNLKMLLPYSFEILFVQYIFLLIGFVSVVFTSILINKSIYRVSALISF
                     LFLVLEILVFIISIEFIIPYEYSNVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            2263..3531
                     /locus_tag="ACOIAP_003371"
     CDS             2263..3531
                     /locus_tag="ACOIAP_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640243.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYDEVIISKNGVRNNTNPTSIIRNDYLNIDKKYSDFVNDKG
                     KDLIYKDDLNIGEAYTSVKYDLVQGMNALNDCIKVSNKNLKSGAEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISSSKVNNICILKIDIKNKSYKLLNRFNLVLQNG
                     YQQNINEIKFSIGSKLYLEIVNNQSTNEDIEEHDNYSNFIIYDIEENTFNISDKFMDN
                     LNKEKNANPKEIGLLGKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNKIKLEDYE
                     ILDLKVDYNEASSGIRKVKLLDDKIYSISGIKNNLSGELKGFKGVVDIVGTNPVKFKV
                     FDMKLKKTVYEAELINGDVSLQEKLFFVAN"
     gene            3888..5069
                     /locus_tag="ACOIAP_003372"
     CDS             3888..5069
                     /locus_tag="ACOIAP_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2640244.1"
                     /translation="MNKKYIKAGNLIDGTGNSTMQNKGIIIDGDTIVEIEDIREDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKVYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVDGNPIENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(5211..6128)
                     /locus_tag="ACOIAP_003373"
     CDS             complement(5211..6128)
                     /locus_tag="ACOIAP_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotA family spore coat protein"
                     /protein_id="HGZ2640245.1"
                     /translation="MENNKCREDFRFTQEYEEDYMNANDRYYENYQVADRYYNYPNKY
                     KEPKMTKCCCKKSMREALELLRYDSLRPFVNFNQFAFISDFFIVGAYLVGIDYSIPPK
                     DNLSGLNGTFERFSACNCDLIDISGQLYYPKPVPLTLGGLVTSIGTIPGVSELVALIE
                     AAVPATIDLGSILNSILDYIIDYIISTVNPLTNVDLASLCNLKAVAFNVTPADYEDFI
                     SSLAYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVLVLGNSNDSRIYFVCVDSIDYIA"
     gene            6381..7175
                     /locus_tag="ACOIAP_003374"
     CDS             6381..7175
                     /locus_tag="ACOIAP_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640246.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKIKTKKEEFFAVNNVS
                     FKVIEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINVSGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEEIEESIENVVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGEIIASGTPQSLKEESGVNNLRDVFIKLARREDI"
     gene            7176..9236
                     /locus_tag="ACOIAP_003375"
     CDS             7176..9236
                     /locus_tag="ACOIAP_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit/CPBP
                     intramembrane protease"
                     /protein_id="HGZ2640247.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKNIKNTSSDKGKIRVLDVDNYK
                     KSLEENKIDAYIKIEEKKSSTSYRIYINSSQENSSNAVKRIETVLDKYKRSTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMTFILVSGGISNQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGIVGIIMTQFIIISLPLLFAYYIKADFKEVFSLKIPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQSMEVAENLNKALFMKDSVLLNLLVIALLPAICEEIFFRGFIFSSF
                     SKSKDKNKSIKLTIICSSVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNGVAVMLNHYTTGNIINLYKFVEVDFSNLNVLEFALILLISLILVMLGARALGRK
                     SLRN"
BASE COUNT         3729 a          895 c         1448 g         3211 t
ORIGIN      
        1 atataaataa attttatata cttttaatca ctttgttgat tatagtaggc ttatattttt
       61 caacaatata tataagtata atcactttat ttagaaaata ttatatggct ataggatttc
      121 aatttaataa tttagtagca ggattattaa gttttttaat tataatgttt attctaaatg
      181 gaatatctta tttgttaatt aaaaagaaaa tatctcttta ggaggggtgg tatgaaatta
      241 aaatctaaaa tatctatact tattatattt ttgactttag caatatattt tagtataggt
      301 ttattaaata atgaagataa cttaaagata aaaactataa aaggagatcc taatgaatta
      361 gactatataa acataaattt tggatatgct tttaatggat atgtaaattc atattataca
      421 ataaatggaa gtaacaaaac caaaaagact gaattaataa aactacaaaa agatgctaag
      481 aacacaaata atttaattga tgtatctagt ggttcagatt taattgctca tgttggattt
      541 gaaatgaatg atgactcaaa agatataaac tttgtaatag atgaaaaaaa agaagattta
      601 gaaaaaggtg tatttccatc agaaggagat gataaagcag ttgaatatga aaaactagat
      661 atgaatgatt ttacaaggac aagatataaa gtagataaaa gttctgataa ttactatgca
      721 aatatactat catcaaaaag atataaaaaa tacttatatg tatctgtact ttatgctaca
      781 agtgattcat caaaaaacaa caaagaatat tcaagtacta tagatataat aaaaataaat
      841 ccagaaaata aaaaaatcca gactataaaa agtataaatt taagtaatta tttttctaaa
      901 aaataccaaa atatagataa tataagtgta agttatgcta gcaaatatga ggataagatg
      961 tatattttag taaatgtatt aaatgcaaat acaggtgata aaagtaattc taaatttcac
     1021 ttacttgagt ataatcttga agaaaataag gaaagcataa tggaattaaa aactgatagc
     1081 aaaatggctt tagcaaaagt aaagttagaa gataataaat tatatatggt aatgtcaaat
     1141 gactatgata atagttcaat tacagagtta aatttactta cctataatat attagataaa
     1201 agcttagatg aagataagta tattttagat aataaagaaa aaagaggaat tagaagtatt
     1261 gaaattgatt caaataaaat cattgtatat acatcaaggt taaattctac attatcttgg
     1321 gataataaat ttatgttata tataataaat aaaaattcta aggaaattgt atatgaagga
     1381 gaattacaat ttaacagttc aaatagtatg ttagaatttg aaataaagta ggtgagttga
     1441 tgaaagattt aataagatta ttcgaatttg aattaaaaag aaatataaaa aattatatat
     1501 ttataataat ctgttgttgt tcctttgtaa ttttaaacat agtaaaaaat ttaaatgact
     1561 ataattacat aatagaaaat gcagttaaaa gtgaacagtt aacaaaaata ggaaatacta
     1621 tagaaacagt aaatgctata ggtttctcaa gttttagaaa tataatgggt tatacagaat
     1681 catggtttat gtttggtata attgtatgta tatgctatgc tttttttatt tggtatagag
     1741 actttaatgg gagaagtaaa tctatatata cacttataat gatacctaaa aatagaatta
     1801 atatttatat atctaaatta ttaaatatat tatttctagt gtatagctat acagtagtac
     1861 ttacaatatc tttatttatt acaagtaagt tgttgcctag acatatgctt gggaatgtta
     1921 caagctatgg ttttgtacaa gaaacaatat ataatctaaa aatgttactt ccatatagct
     1981 ttgaaatact atttgtacag tatatatttt tattgatagg atttgtatct gtagtattta
     2041 catcaattct tataaataaa tctatttata gagtaagcgc tttgataagt tttctatttt
     2101 tagttttgga aattttagtg tttataattt ctatagaatt tattatacct tacgaataca
     2161 gtaatgtatt tactgttcta tattcaagta taaacatatt tgtatgtagt cttatatcta
     2221 ataaactttt gaagcaaaag attgactttt aggagggata ttatgaaagc aaaaaatata
     2281 ggaaaatata caatatgttt tataatagtg tgttttttaa tgattactat gaccttaata
     2341 ttgagttatt ttaataagga taaattatct gtaaaaactt taaaaggcaa tgtaaaagat
     2401 ataggtagag tgagtgtagt atatacacct aatataagta aattttctta tgatgaggta
     2461 attataagta aaaatggagt aagaaataat acaaatccca catcaataat tagaaatgat
     2521 tatttaaata ttgacaaaaa atacagtgat tttgttaatg ataaaggaaa agatcttata
     2581 tataaagatg atttgaatat aggagaagca tatacttctg ttaagtacga tttagtacaa
     2641 ggaatgaatg ctttaaatga ttgtataaag gtttcaaata aaaatttaaa aagtggggca
     2701 gaagaaaatt ttgatattaa tttaaacaag tctgatttta aagaaaacag ttggaaaact
     2761 ttgtttaata aaatatataa aggcaattta tatatggtga ttagtgaaac taatatttca
     2821 agttctaaag tcaataatat ttgtatatta aagatagata taaaaaataa gtcttataaa
     2881 ttattaaata gatttaattt agttttacag aatggatatc aacaaaatat caatgaaatt
     2941 aaattttcta ttggaagtaa attatattta gaaatagtaa ataatcaaag tacaaatgaa
     3001 gatattgaag aacatgataa ttactctaac tttattatat atgatataga agaaaacact
     3061 tttaatataa gtgataaatt tatggataat ctaaataaag aaaagaatgc aaatccaaaa
     3121 gagattggtt tattaggtaa aactaagcta gattatatgg taaaaaataa taaattaaat
     3181 cttatagtta cagatatgag taattctata acaaatcttg tttatgatat taattctaat
     3241 aagattaaat tagaagatta tgagatactt gatttaaaag tggattataa tgaagcatca
     3301 tctggaatta ggaaagttaa gttactggat gataagatat attctatttc aggtataaag
     3361 aataatctat caggagaatt aaaagggttt aaaggggttg ttgatatagt tggaactaat
     3421 ccggtaaaat ttaaagtatt tgatatgaaa cttaaaaaaa ccgtttatga agctgagcta
     3481 ataaatggag atgtaagttt acaagaaaag ttattttttg ttgcaaatta agtgatggaa
     3541 ttaattttat aactttaaac ttttatatgt attgtaggtg aatataagta aaggagtgtc
     3601 ttaaaatgaa ttttttagct catgagacac tcttttttat atgaaatcaa atatattttt
     3661 atcatttaga caatgaaaaa taagattatc tctattttaa gacagacatt tgtttataat
     3721 tatatacaaa aacatttttt aatatttttg tatagtatat aataatttaa tttatattaa
     3781 tacacttaaa tttgaaatag aatgagtata atggtaaaat taattattag aatattagaa
     3841 ataataaata aataatacat tgtacttaaa agggggagaa atttaagatg aacaaaaaat
     3901 atattaaagc aggaaattta attgatggaa caggaaatag taccatgcaa aataagggta
     3961 taattattga tggagatact atagttgaaa ttgaagatat aagagaagat ttaaatggct
     4021 atgatgtgta tgattactta gataaaactg ttatgccagg tattatgaat tgtcatgttc
     4081 acttgacaat ggagccagtt ggaaatccaa aagtatatta tgataatgta tcagatgtag
     4141 agcttgtagt aaatacgata aaacaacttg atgcttattt ggattcagga gtaacatata
     4201 ttagaagtct aggttgccca aaatatgtgg atgtacaact taaaaatctt atagacaaag
     4261 ggtctataga tggtcctggt atagttactt caggtccagt tatatgcatg acaggagggc
     4321 atggatacta ttttggtatt gaaagtgatg gagtggacga atgtagaaaa tcagccagaa
     4381 cagttttaaa aaatggagta gattgtgtaa agataatggc aactggaggt gtaacaactg
     4441 atggggttga accagggtca ccacaattaa ctttggagga aatgaaggct gctgtagatg
     4501 aagctataaa ggcaggcaaa ataactgcca cacatgcaca aggaagaact ggtataaaaa
     4561 atgcagtgct tgcaggaatt acttctatag aacatggtgt ttatttagat gatgaaataa
     4621 ttgatttaat gcttgaaaga ggaacttact tagttccaac tgttgctgca ccatatttta
     4681 ttctaaatgc aggaaaagaa agtggaataa ctgaagctac tcttagaaag tgtgagattg
     4741 ttgctattcc acacaaagag tcatttctaa aagcatataa aaaaggaatt aaaattgcag
     4801 ttggttctga tgcaggaact tcttataatg aacatggaaa aacatattat gaaatgaaac
     4861 taatgtcaga ttatggcatg gataatatgg atataatagt tgctgctaca aaaacagcat
     4921 ctgaactttt aagaattgat aaaaattatg gaactttaga aaaaggaaag aaagcagatg
     4981 ttatagttgt agatggaaat ccaatagaga atatagatgt acttgcagat gtgttagcag
     5041 tatttaaact tggtaaaaaa gttagataag taatataaaa aataaaaaag agtgtctaaa
     5101 gggattttta aataattata gacactcttt tttattagta acaattaagt cttttatact
     5161 ttagggacta gattctattt tatatttaga tataactctt taaaatcatt ctatgcaata
     5221 taatctatag aatctacaca tacaaagtat attcttgaat cattagaatt tccaagtact
     5281 agaacatcat ttttcttacc tagaacttca acaccagtta gaaccaaact accagctact
     5341 acagtaactt gattatttat attagacata taaagattat ctaggatacc tttattacaa
     5401 cagcagtcgt cacaatcaca gttacaatta cattctttat aatgcttttt gtcaagatag
     5461 taagctaaag atgatatgaa atcttcataa tctgcaggtg taacattaaa ggcaacagct
     5521 ttaagattac ataatgatgc taaatctaca tttgttaatg ggttaactgt agaaattata
     5581 taatcaatta tataatcaag tattgaattt agtatagaac caaggtctat agtagcagga
     5641 actgctgctt ctataagagc gactaattcg gatactcctg ggatagtacc aattgaagta
     5701 actagtcctc caagtgttaa aggaacaggt ttaggataat acaattgacc agatatatca
     5761 attaaatcac agttacaagc tgaaaatctt tcaaaagtgc cattaagtcc agataaatta
     5821 tcttttggag gtattgaata atctatacct actaaatatg caccaacaat aaagaaatct
     5881 gaaataaaag caaattgatt aaaatttaca aaaggtctta gagaatcata tcttaaaagt
     5941 tctaatgcct ctctcatgct ctttttacaa caacattttg tcattttagg ttctttatat
     6001 ttatttgggt aattatagta tctatcagct acttgataat tttcatagta tctatcattt
     6061 gcattcatat aatcttcttc gtattcttga gtaaatctaa agtcctctct acatttatta
     6121 ttttccatta aatacactcc ttttatattt tgatttaaat gtatagataa ttaagtttat
     6181 ctatatagta atattatatt tattgtgtaa aaaaatgtta caaaagaaat tataaatgaa
     6241 taaaaaataa taatttgtca aataaactca taaattatta tgaataatct attctaaagt
     6301 aaaaaactat gtataaaaaa ggtttatatg ttatatttat ataaatataa catatgaatg
     6361 agaaaggagt agtttgataa atgattgagg tagataaatt atgcaagtct tttacaaggg
     6421 ttgtaaaaga tgataagaat aaaagttcaa taagaaagtt aaagaaaata aaaactaaaa
     6481 aagaagaatt ttttgctgta aataatgttt catttaaagt tatagaaggt gaaattgttg
     6541 gaatattagg gccaaatggt gcaggaaaaa ccacattact tagaatgtta ggtggcatat
     6601 taacaccaac atcaggaagt ataaatgttt ctggatatga ttattcaata gatagaaatt
     6661 cagccaaaaa agaaataggc tatctgtctg gaaatacaaa actatatgga aggctttctc
     6721 ctagagaact tctaacaact tttgcaagtc tatatgagat gtcaaaagaa gagatagaag
     6781 aatcgattga aaatgttgta aaaataatgg atatgagtga atttatagat aatagaattg
     6841 aaaatctatc aactggtcag acccaaagaa catctatagc tcgttgttta atacattctc
     6901 caaaagtata catttttgat gagccaacac taggtctgga tgttttaagt agtgcatcca
     6961 ttatagattt tatgaagaat gaaaaactaa ggggaaaaac tgttctttac tcaactcatt
     7021 atatggaaga agcagaaact ttatgtgaca agatttttat gattcacaat ggggaaataa
     7081 ttgcatcagg aactccacag agtttaaaag aggaatctgg agtaaataat ttgagagatg
     7141 tatttataaa acttgccaga agggaggata tttaaatgag aagtaagatt gtaaaataca
     7201 tatttaaaaa agaaatgtta gacatattga gagataaaaa gactttattt atgatgattg
     7261 ttgtgccact tcttttatat cctttactta tgttgttgat gattcaagta atgaatatgt
     7321 ctgcaagtag tatgaatagc aaggacatta atatagcttt caataataaa ccaaataaag
     7381 tgttagtttc catgattgaa gatgataatt tagaaaaaaa tattaaaaat acttcaagtg
     7441 ataaaggaaa aataagagtg ttagatgtag ataactataa aaagtcatta gaagaaaata
     7501 aaattgatgc ttatataaag atagaagaaa aaaaatcatc tacaagttat cgaatatata
     7561 taaattcttc tcaagaaaat tcttctaatg cagtaaaaag aattgaaact gttttggata
     7621 aatataaaag atctactata gaaaagactt tatctgaaaa aggattagat gtacaagcta
     7681 ctttagaacc aataacatat agcactgtag atgttgcaaa gacagaagaa gtggcaggat
     7741 actttttagg tcagatacta ccatttatat taataatagg agttttacta ggttcaatat
     7801 atccagcaat agatgttatg gctggagaaa aggaaagagg tacgttagaa acattattta
     7861 cacttccaat atcaaactta gaactagtta tgggaaaata tatggcagtt tctcttagtg
     7921 caatagtaac agcaatttta aacattttat ctatgggact gactatgaca tttattttag
     7981 ttagtggagg tattagtaac caatttggct ttggaaactt taattatgga gatttagtct
     8041 tgccaattat aactacctta atttgcatat gtcttttttc aatggtagtt tcagcaataa
     8101 gtatgtgtgt atgttcatta gcaaaaagtt ttaaagatgc ccaaaactac ataacacctc
     8161 ttatgttaat tattatgata ccatcatatg tttctatgat acccaatata gtattggata
     8221 gagtaacagc tgtaatacct gtagtaaata tatctttact tataaaaagt gtattatcct
     8281 ttaaaagcga tttaaattta atagctttag ttttagcatc aaatgtagcc tttgttatat
     8341 tggcaataat actactgtct aagatgttca attctgagga aatacttttt ggtaatagta
     8401 agagtttctc tttcttagag aaaagaagta atataaaaaa agggtctata ccaactgtaa
     8461 gtgatggtgt tattttatat gcagtaggat tagttttatt gatttatgtt ggttctttag
     8521 ttcaaattaa atttggtata gtaggtatta taatgacaca attcattata atttctttgc
     8581 cattattatt tgcatactat attaaagctg attttaaaga ggtatttagc ttgaaaattc
     8641 ctaaattaaa gcacgtgttt gggagcattg ttctttggat tggtggttat atacttatta
     8701 tgattataac acagctaatt ttattcttat tccctcaaag tatggaagtt gctgaaaatt
     8761 taaataaggc tctctttatg aaagatagtg ttttattgaa tttactagta atagcattat
     8821 taccagctat atgtgaagaa atatttttta ggggatttat attttcttca tttagtaaat
     8881 caaaagataa aaataagtct atcaagctta ctataatatg tagtagtgta ctgtttggta
     8941 ttatgcatat ggattttatt agaataattc caacatcaat attgggtatt atatttgcat
     9001 acagtgtgta taaatctggt tcaatatttg tatcaatgtt attgcatttt ttaaataatg
     9061 gtgtagcagt tatgttaaat cattatacaa ctggaaatat aatcaactta tataaatttg
     9121 ttgaagttga tttttcgaat ttaaatgtac ttgaatttgc gttaattctt ctaataagtc
     9181 ttatattagt tatgttagga gcaagagctt taggtagaaa gtctttaaga aattaagtat
     9241 aaatttaata tacattaaaa tattaataag cactaaagta tat
//
LOCUS       DBGJFK010000107         9265 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.112, whole genome shotgun sequence.
ACCESSION   DBGJFK010000107 DBGJFK010000000
VERSION     DBGJFK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9265
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.112"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            113..1873
                     /gene="prdR"
                     /locus_tag="ACOIAP_003376"
     CDS             113..1873
                     /gene="prdR"
                     /locus_tag="ACOIAP_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HGZ2640248.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSGQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISERVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKEVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKINVSKI"
     gene            2302..4182
                     /gene="prdA"
                     /locus_tag="ACOIAP_003377"
     CDS             2302..4182
                     /gene="prdA"
                     /locus_tag="ACOIAP_003377"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HGZ2640249.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            4263..4547
                     /locus_tag="ACOIAP_003378"
     CDS             4263..4547
                     /locus_tag="ACOIAP_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBO2463/CBO2479 domain-containing protein"
                     /protein_id="HGZ2640250.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            4585..5310
                     /gene="prdB"
                     /locus_tag="ACOIAP_003379"
     CDS             4585..5310
                     /gene="prdB"
                     /locus_tag="ACOIAP_003379"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050002 - D-proline reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:5035..5037,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HGZ2640251.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            5390..6148
                     /gene="prdD"
                     /locus_tag="ACOIAP_003380"
     CDS             5390..6148
                     /gene="prdD"
                     /locus_tag="ACOIAP_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HGZ2640252.1"
                     /translation="MEEKIIRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKEQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            6163..6630
                     /locus_tag="ACOIAP_003381"
     CDS             6163..6630
                     /locus_tag="ACOIAP_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HGZ2640253.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            6656..7129
                     /locus_tag="ACOIAP_003382"
     CDS             6656..7129
                     /locus_tag="ACOIAP_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050485 - oxidoreductase activity, acting
                     on X-H and Y-H to form an X-Y bond, with a disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HGZ2640254.1"
                     /translation="MGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSEHNE
                     WKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIMGVD
                     GLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK"
     gene            7149..8156
                     /locus_tag="ACOIAP_003383"
     CDS             7149..8156
                     /locus_tag="ACOIAP_003383"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HGZ2640255.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            8276..9157
                     /locus_tag="ACOIAP_003384"
     CDS             8276..9157
                     /locus_tag="ACOIAP_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HGZ2640256.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWVNVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT         3629 a         1142 c         1857 g         2637 t
ORIGIN      
        1 agttacttaa taaattttaa taataattat ttaataaata attattataa tatgctagaa
       61 taaatatata taaataagtt ttgatgatgt actattataa aggggggact ttatgttttc
      121 gataccagaa gtaaaaaaag tagaagaggt aatggataca aaatttacaa ctatagacga
      181 agacacaaga attgaagatg caataaaaga aatgataaaa agtaatacaa aaactctaat
      241 ggtaatagat tcatctggtc aattaaaagg cattatatcc atgacggata tacacaatct
      301 ttatgagatg cataaaaagt atgaaggcca accagtaaaa cttataatga agaaggatgt
      361 aatatatgtc aatgaaggtt taaccttaga tgaatgtaga gatataatga tattaaaaaa
      421 tatagggatt cttcctgttc ttagagataa taaaattatt ggagttctaa aacaagagca
      481 tattagagac tatttatata tgcatttaga agattatgga ttgactttga agtatattat
      541 aggtcaaatt aaagagggaa tttgtgctat aaataatgaa ggtgttgtta tcttgtggaa
      601 taagtttatg gaagaaaggt atgatataaa gtctgaagac atagttggtc gaccgatgaa
      661 tgagtttttg gaaaatacta tttcagaaag agtgctaaat agtaaagttg gaatgagtga
      721 cctgtatttt acggataaaa aagaaaatat gtatgcatta gtccatgcaa atcctatatt
      781 ttataaagaa gaatttatcg gtgttgtatg tacagaagtt gatgttacag aagctaagat
      841 attagccctt gaacttgaaa aagtaaatga tacattgaaa tatctaaaaa acgaagtcaa
      901 aaatttatct aaaggtagtt ttgataagat tttaggtaaa agttataaac tggaaaaatc
      961 gaaagcgatt gcaaaacaag tggctagaac aaatagtagt atatttattt ggggtgaaag
     1021 tggtacaggt aaagaagtat ttgcaagagc tattcatgat tatagtgaga gaaaaggtca
     1081 atttatacct gttaactgta gtgctatacc aaatgagtta tttgaaagtg agttttttgg
     1141 gtatgaatca ggtgcattta caggagcaag taaaaaaggt cgaataggca tatttgaact
     1201 tgcaaaggat ggaactgtat ttttagatga aattgccgat ttacctctta gtatgcaggc
     1261 aaagttgctt agagtgttac aggaaaaaga aataagaaga gttggtggag atactacgat
     1321 aaaaataaat cctagaataa tatcagctac caataaagat ttgagtaaaa tggtaaaggc
     1381 agaaaaattt agagaagatt tatactatag attaaatgtt gttgaaataa agattcctcc
     1441 acttagagag agaaaagaag acataggatt attggttcat agttttttgg aggagatatg
     1501 caaacaaaat aataagcctg tacttacaat tagcaaagag gtaatagata tatttcagaa
     1561 ttatagatgg aaaggcaata tcagagaatt aaaaaatacg attgaaaata ttgttgtatt
     1621 gtcacaaaat tctaaaatag atgtggatga tgtaccaagt tatatgatgg attctacaaa
     1681 taatagtact gaagaagaag agtatccctt agatttaacg aaggccactc aaaaaattga
     1741 aataaagaat ataaccaagg cacttaaaat gtctaatgga aataaagcta aagcagctaa
     1801 gatattaaat atacccagaa caacattgta ttataagata gaccaataca aaataaatgt
     1861 gtctaaaata tgacacatga ctaaattttg acaaaatgat aaactttaat ttaaaaccta
     1921 gtgagaccaa tgcttgtatg agtgtcgtat atatagatgt gttaaaaaaa atgaaaaagt
     1981 gttgattaat tgacactttt tttatttgag aaaatgttta caaatacaaa aaataacata
     2041 tttaaaataa atatttatat aatatttggc taaaaatagc gatagatgaa gaatctatta
     2101 tagaaaaaat ctttttgtta ataagttggc ataggaattg cttataatat aaagtgactt
     2161 taagtgagaa aaaaataata ttaatcataa caaattatgt aggttttaat ttacttaatt
     2221 tctcagttaa ggggttacct gttgaggaat tgagatttaa aataataaat aagaaaataa
     2281 tgtaaggagg tattttatac tatgtcaata actttagaaa cagctcaagc ccatgcaaat
     2341 gacccagcag tttgttgttg tagatttgaa gcgggaacaa ttatagcgcc agaaaactta
     2401 gaagatccag caatatttgc agacttagag gattctggat tattaacaat accagaaaat
     2461 ggattaacta taggtcaagt actaggagct aagttaaaag aaactttaga tgctctttct
     2521 ccaatgacta cagataacgt agaaggatac aaagcaggag aggctaaaga agaagtagta
     2581 gaagaaacag tagaagaagc agctccagta tcagaagcag ctgtagttcc agtaagcaca
     2641 ggagttgcag gtgaaacagt taaaatacac ataggtgaag gtaagaacat aagcttagag
     2701 atacctttat cagtagctgg tcaagcagga gttgctgctc cagtagcaaa cgttgctgct
     2761 ccagtggcaa gtgcagcagc agaagtagct ccaaaagttg aagaaaagaa acttttaaga
     2821 agcttaacta aaaaacactt taaaatagat aaagttgaat ttgctgatga aactaaaata
     2881 gaaggaacta ctttatacat cagaaatgca gaagaaatat gtaaagaagc taatgaaact
     2941 caagagttag ttgtagatat gaagttagaa ataataactc ctgataaata tgaaacttac
     3001 agtgaagctg tattagatat acaaccaatc gctactaaag aagaaggcga attaggttca
     3061 ggtataacta gagttataga tggagctgta atggtattaa ctggtacaga tgaagatgga
     3121 gttcaaatag gtgaatttgg ttcttcagaa ggtgagttaa atactactat aatgtggggt
     3181 agaccaggtg ctgctgacaa aggtgaaata ttcatcaaag gtcaagtaac aataaaagca
     3241 ggaactaaca tggaaagacc aggaccttta gctgctcacc gtgcatttga ctatgtaact
     3301 caagaaataa gagaagcatt aaagaaagtt gacaactctt tagtagttga tgaagaagta
     3361 atagagcaat acagaagaga aggcaaaaag aaagttgttg ttataaaaga aataatggga
     3421 caaggtgcaa tgcatgataa cctaatatta ccagttgagc cagttggtac attaggagct
     3481 caaccaaacg ttgacttagg aaatatgcca gttgtattat ctccacttga agtattagat
     3541 ggtggtatcc atgcattaac ttgtatagga cctgcatcaa aagaaatgtc aagacattac
     3601 tggagagagc cattagtaat aagagctatg gaagatgaag aaatagattt agtaggtgtt
     3661 gtatttgttg gttctccaca agtaaatgct gagaaattct atgtatctaa gagattaggt
     3721 atgttagttg aagctatgga agttgatgga gctgtagtaa ctactgaagg ttttggaaac
     3781 aaccatatag atttcgcatc tcacatagag caaataggta tgagaggtat accagtagtt
     3841 ggtgtaagtt tctcagctgt tcaaggtgct ctagttgttg gtaataaata catgactcac
     3901 atggtagaca acaataagtc taagcaaggt atagagaatg aaatattatc taacaatact
     3961 ttagctccag aagatgctgt tagaataatg gctatgctta aaaatgctat agaaggtgta
     4021 gaagttaaag ctcctgaaag aaaatggaat ccaaatgtta aattaaataa catagaagct
     4081 atagaaaaag ttacaggaga aaaaatagta ttagaagaaa atgagcaatc tttaccaatg
     4141 agtaagaaga gaagagaaat atacgaaaaa gacgaaaact aaaatttaga tattaactaa
     4201 gatttagaca ataacataaa tttagatcca agtttaaaac agtatagaga ggtagaatta
     4261 taatggatag gttaaaatat atctcatcag agacttttta tgaaggtatt atagttgaca
     4321 tcaaaggtgg tggagtgact atagacctaa aaggtagact tggacaattt aaaataccta
     4381 atagaatgct tataactgac tacgaactta agataggtca agaagttgga ttcatgctaa
     4441 gctatcctga ggtattaagt ccagagccta atcaagagta tgtagaaaat attaggagag
     4501 aaaaagaaaa acaagcagaa atgcaatcaa aacaagaaga aaaataataa ataatcgttt
     4561 gaaaatagaa gggagaggaa atatatgagc cttacaacag tacaaggact tcaatctgaa
     4621 atattcgttc caataacacc tcctccagtt tggactcctg taactaaaga attaaaagat
     4681 atgactatag ctttagctac agcagctggt gttcatttaa aatctgacaa gagatttaat
     4741 ctagcaggag atactacatt tagagctata cctaatacag ctacagttga tgaaatgatg
     4801 gtatcacatg gtggatatga caatggagat gtaaataaag atataaactg tatgttccct
     4861 atagatagat tacatgaatt agctgcagaa ggatttatca aaggagtagc tcctatgcac
     4921 tatgcattca tgggtggtgg aggaaaccaa catgtcttca ctgaagaaac tggtcctgct
     4981 atcgctgcta aacttaagga agagggagta gacggtgtag ttatgacagc tggctgaggt
     5041 acttgccata gaactgccgt gatcgtgcag agagcaatag aggaagctgg aatacctaca
     5101 ataataatcg cagctcttcc tccagtagtt agacaaaacg gaactcctag agcagttgct
     5161 ccattagttc caatgggtgc taatgctggt gaaccacata acatagaaat gcaaacacat
     5221 atattaagag atacattaga gcaattagtt gcaataccat ctgctggtaa gatagttcca
     5281 ttaccatacg aatataaagc tcacgtttaa aatgtaattt atatttgaaa atatagaacc
     5341 cttctcctac acagttagga gaggggtttt aagaacaaag gtggatatta tggaagaaaa
     5401 aataataaga agacttgtta taaaaccgtt tcatatgaat gaagttaatt tcggttcaaa
     5461 aacttctata aagaaagatg tacttacaat agatttatca agtatagatg aaataaaaga
     5521 aagagaagag ttaataacag acataaaagt agacattata aaacctggag attatgacag
     5581 agaaattaat actattatgg acattatacc aatatcaaca aaagttttag gcagactggg
     5641 agagggaatt acacatactt taactggtgt atatgtaatg ttaactggtg cagatgaaga
     5701 tggaaatcaa atgcatgaat ttggttcttc agaaggaatt ttaaaagaac aaatggtatt
     5761 tgggagatat ggaactccat cagttgaaga ttatataatc catgtagatg taactttaaa
     5821 gggtggttta ccttttgaaa gaacacttcc acttgcagca ttcagagcat gtgatgattt
     5881 tatacaagaa ataagagcgt ctttgaaaat ggaagacgga agaaatgcta ctcaagttcg
     5941 tgaatatttt gacaaaattc gaccaaatgc aaaaaaggtt gtcatagtaa aacaaatagc
     6001 aggtcaaggt gctatgtatg acaatcagtt attctcaaag gaacctagtg gatttgaagg
     6061 aggaacatca attatagata tgggaaatgt acctatgatt atatctccta atgaatacag
     6121 agatggtgcc cttagagcta tgacttaaga gaggtggata ttatgggaat aggaccttca
     6181 acaaaagaaa catctcttca tcactttaga gacccacttt tagacatagt tgaaagtgat
     6241 aaggatgtag atttacttgg agtaatagta gtaggaactc cagatggaaa tgaaaataaa
     6301 acctttgtgg gacaaagaac ggccgcttgg ctggaagcca tgagagtgga tggagctata
     6361 gtttcatcag atggttgggg aaactcacat gttgactacg ctaacacatt tgaagaaata
     6421 ggaaaaagag atatacctgt agttggagtt acatttaatg gtacccaagc taagtttgtt
     6481 gtaagcaatc aatatatgga taccatagtt gatatgaaca aatcaaaaga aggtattgag
     6541 acagaagttg ttggagaaaa caacacaaat gaaatagatg ctaaaaaagc tttggcattt
     6601 ttaaaactta aaatgagaaa acatgggtaa aaaatttaag taaggaatga gttttgtggg
     6661 aatttctaca tcaatgaaaa acacatcact tcatatattt agagacccat tactagattt
     6721 gatagataat gattctgaca tagacttgtt aggagtggtt gtagttggga catcagagca
     6781 caatgaatgg aaaacatttt tagcaactag acttggaaga tggattgaat cattgcgacc
     6841 tgatggagtg attataactt tagatatggc aggaaaccag catattgatt ttacaaatgc
     6901 tatagcagag tttgtaaaat cagatatacc tacagtaggt cttactatta tgggagtaga
     6961 tggattagta attaccaatc catatttaga taaagctacc ataattgatt ataaaaagac
     7021 aacaggctac atagaaacag aagtagttgg agacaatcat atggacgaag ttgatgttaa
     7081 aaaagcattg gctttcctaa aattaaaaat gcgtaaagac gcaaaataaa cctaaggggg
     7141 aatttgatat gaaatttagc agaagtatac aagctataga ctctcataca gcaggtgaag
     7201 caactagaat agttgtaggt ggaataccta acataaaagg aaattctatg cctgagaaaa
     7261 aagaatattt agaagaaaat ctagattatt taagaactgc tataatgtta gagccaagag
     7321 gacataatga tatgtttggt tctgtaatga ctcaaccttg ttgcccagat gctgactttg
     7381 gaataatctt catggacggt ggcggatacc ttaacatgtg tggccatggt acaataggag
     7441 ctatgacagc agctatagaa acaggtgtag ttccagcagt agagcctgta actcatgtag
     7501 ttatggaagc tccagcagga ataataagag gagacgttac agttgtagat ggaaaagcta
     7561 aagaagtatc attcttaaac gtaccagctt tcttatataa agaaggtgtt gaagttgact
     7621 taccaggtgt tggaactgtt aaatttgaca tatcatttgg tggaagcttc tttgctataa
     7681 tacatgcaag tcaattaggt ttaaaaatcg aacctcaaaa tgctggtaaa ttaactgaac
     7741 tagctatgaa acttagagat ataataaatg agaaaataga aatacaacat ccaactttag
     7801 ctcatataaa aactgtagac ttagttgaaa tatatgatga gccaactcat ccagaagcta
     7861 cttacaaaaa cgtagttata tttggtcaag gtcaagttga cagatctcca tgtggaactg
     7921 gaacaagtgc taaattagct actttacatg ctaaaggtga attaaaagta ggagaaaaat
     7981 tcgtatatga aagtatatta ggaactttat tcaaaggtga aatagttgaa gaaactaaag
     8041 ttgcagattt caatgctgta gtacctaaaa taactggttc tgcttatata actggattta
     8101 atcattttgt aatagatgaa gaagatccac ttaaacatgg atttattctt aaataagtaa
     8161 taaataaatt aggaaattaa aatagaatag tagccactta tcggctacta ttctatagct
     8221 tttaggctat aagattcaga atatatgaaa aaataaaaaa ataggaggat ggattatggt
     8281 agcaatctta aaggcattat acgtagtatt cgcagcaatc tttgcagttg tgtttggtaa
     8341 agacgtagct aaagcaaaca aagaggggaa actagaagaa caaagtactc caaaagttgc
     8401 tgtaacagga tttataacag acttctttga tacattagga atagggtcat ttgctccaac
     8461 aatagcaatg tcaaaagctt taaagctaaa tataccagat aaaaaaatgc ctggtacatt
     8521 aaacgtagca catactattc cagttgttac agaagcattc atatttacat caatcatacc
     8581 agttgatggt gttactttag tatctatggt tgtggcagca gcagttggtt catacatagg
     8641 tgcaggaata atagctaaga tggacgagag aaaaatacaa cttgttatgg gtgtaacttt
     8701 agcattaaca gcaatattaa tgttattagg tcatccttgg gttaacgtat taccaggtgg
     8761 aggaaatgaa ttaggtctta ctggtgttaa attagtaata ggtgtaatag gtaactttat
     8821 actaggagct ttaatgacag ctggtatagg tctatatgct ccaggtatgg caatggttta
     8881 tttcttagga atgtctgcaa aagttgcatt cccaatagtt atgggttctt gtgcattatt
     8941 aatgccagtt gcaagtatga aattcataaa agaagacgca tatactaaaa aagcatcagt
     9001 tataatagct atatgtggtt taataggagt tttcgtagct gcatatatag taaaaactct
     9061 accaatggat atattaaaag cattagtaat agtagttata gcttatactt ctgctacaat
     9121 gataatggct gcaaataaaa acaaaaagac tgcttagtta aagactactt agtgtttatc
     9181 aaatattaca gctaataata aagattataa actgctttaa aatattgaat taatatttta
     9241 gagcagtttt tttatttact aatat
//
LOCUS       DBGJFK010000108         9045 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.114, whole genome shotgun sequence.
ACCESSION   DBGJFK010000108 DBGJFK010000000
VERSION     DBGJFK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9045
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.114"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            65..1468
                     /locus_tag="ACOIAP_003385"
     CDS             65..1468
                     /locus_tag="ACOIAP_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640257.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISPDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASTKDKEEILKVVDPEGKLDVSTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVINFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            1495..3039
                     /locus_tag="ACOIAP_003386"
     CDS             1495..3039
                     /locus_tag="ACOIAP_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HGZ2640258.1"
                     /translation="MNNEGTFEELSGRLRNKKLCDLIMNADEAAKFIKDGMVVGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEDGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGIVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            3070..4461
                     /locus_tag="ACOIAP_003387"
     CDS             3070..4461
                     /locus_tag="ACOIAP_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HGZ2640259.1"
                     /translation="MGKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKIAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKAQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            4654..6150
                     /gene="abfD"
                     /locus_tag="ACOIAP_003388"
     CDS             4654..6150
                     /gene="abfD"
                     /locus_tag="ACOIAP_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HGZ2640260.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSTDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKTIAGIKKEEALNL"
     gene            6285..6560
                     /locus_tag="ACOIAP_003389"
     CDS             6285..6560
                     /locus_tag="ACOIAP_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640261.1"
                     /translation="MTCGVRFCGGCNPRYERGKALAIIKEHFNGRVDFSIAQENLEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            6584..7891
                     /locus_tag="ACOIAP_003390"
     CDS             6584..7891
                     /locus_tag="ACOIAP_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase C-terminal
                     domain-containing protein"
                     /protein_id="HGZ2640262.1"
                     /translation="MSWRELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPTFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSDFDYIVEKSQPLYELEPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFVNNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAIEFEKRFKEKY"
     gene            7911..9029
                     /locus_tag="ACOIAP_003391"
     CDS             7911..9029
                     /locus_tag="ACOIAP_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HGZ2640263.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVPPKKIKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     AQIDEFTDSTIANQQRLLANNYVELNREEIREIFANLY"
BASE COUNT         3447 a         1027 c         1858 g         2713 t
ORIGIN      
        1 tagagtctta gggagaaagg agaaatatat tttttaataa tatttgttaa tttaataaca
       61 aaaaatgaaa gggagtgatt tggtgaagtt tgaattgatg gattttttaa tgaatccttt
      121 tgtccttatg tttgctgcag taattacagg aattttattt ggaaaaatta aatttgggaa
      181 gtttaatttt ggggtatcag gagcattatt tacaggatta tttattggat ggcttgcata
      241 tagcttggga aatttaataa tagcaaaagg agaaacagca gcaggatata aggcagcaac
      301 tgtaatgatg gggaatggaa ttatttctcc tgacttcttt gatttctttt taataatatt
      361 tgttgcagca gttggtctat tggcagcaaa agatatgaaa gctgtattaa agaagtatgg
      421 agcaagattt gtaattttag gcgttcttat aactttcata ggtggctcta tgacttatgc
      481 aatgacttta ttatcaagtg ataaaggaag tagcgcttat gaagtttctg gtgtttacac
      541 aggagcatta acaagttcac ctggattagc cgctgcttta gaaacagctg gtaaacatgc
      601 agaagatgta tcaaaagaat ttgaaaaagc ttcaacaaaa gataaagaag aaattttaaa
      661 agtagtcgac ccagaaggaa aattagatgt gagcacaact acatcactga ctcaagagca
      721 aatagataag tacattgcat atgctgaagc tggtgttggt ataggtcatg cagtcgcata
      781 tccttttgga gttttaatag taatcttagg tgtaaatttc cttccaaaat tatttaggat
      841 ggaccttaaa gaagaaagaa gaaaatatga gaaggaaatg aaagaagcaa gagatagtgt
      901 ttctggtaaa acgataccag aagtcccatt taatataata acatttttct tgacatgttt
      961 agctggatac ttagttggag gaatacatgt atttatggga ccactagggt actttacact
     1021 aggagcaaca ggaggttcac taattgtatc tctagttctt ggatatatag gtaagatagg
     1081 ggtaataaat tttagaatgg aagaaaaggt tttaaatatt ttaaaacaaa tagggctagt
     1141 atttttctta gcaatagttg gattaagata tggtggaaaa gtagttgatt caattatgac
     1201 atctggtatg cacctagctt tagtagcaat agcagtgggt gttacagcta tgatgatagg
     1261 attcttagtt ggtaaatatg tatttaaatt aaattggatt ttactatctg gagctgtctg
     1321 tggtggtatg acatcaacac caggccttgg agctgctgtt gatgctcttg atagtgatga
     1381 cccagcagca ggttatggtg ctacgtatcc atttgcatta ttaactaaag ttatattggt
     1441 tatagtttta cacaaacttc caatgtaaat aagattttat atggggggat atttatgaat
     1501 aatgaaggaa catttgaaga actaagtgga agattaagaa ataaaaaatt gtgtgattta
     1561 ataatgaatg cagatgaagc tgctaaattt ataaaggatg ggatggttgt tggagttagt
     1621 ggatttacac cttcaggtta tccaaaagca gtaccattag cagtttcaga aagagctaaa
     1681 agtggagaaa agataaaatt aactgtatat tcaggagcat ctttaggtcc agaagttgat
     1741 ggagcatggt cagaagcagg tataattgaa agaagacttc cttatcaaac taattcaata
     1801 cttagaaata atattaataa aggtgttgtt gattatatag atatgcacct aagtcattct
     1861 actcaatttt taaattatgg aactataccc aaagtagatg tagctatagt agaagcactt
     1921 gcaataactg aagatgggaa tattatacca actagtggaa taggtaattc tccatctttt
     1981 ataaaaagtg cagataaagt aatagtagag ataaatcttg caaaaccaat ggaaatggaa
     2041 ggtatggcag atatatatat tacggaaaat ccaccaaata gaaaaccaat agaaataaat
     2101 catcctaaag atagaattgg aacaacatat ataccttgtg gtttggataa aattgcagga
     2161 atagtaatta ctaatatgca agataaaacc cgaccattgg gtgtagtaga tgaagcttcg
     2221 aaaaaaatat caaataatat tattgctttt ttaagagaag aagtaaaggc aggtagactg
     2281 tcaaagaatt tacttcctct tcaatctggt gtaggaagtg tagcaaatgc agtattatat
     2341 ggattatgtg aatctgaatt tgaaaattta acttgttaca cagaggttgt acaggattct
     2401 atgttggatt taataagaat gggcaaagtc acaatggcat ctactacatc tgtaagtcca
     2461 tctccggaag gattaataaa atttgaaaaa gatattgatt tttttaagga taagattata
     2521 ttaagacctc aagaaattag taataatcca gagatagcta gaagaattgg tgtaattgca
     2581 atgaacactg caattgaagt tgatatttat ggaaatgtaa attccactca tataatgggg
     2641 tcaaagatga tgaatggaat tggtggttct ggtgattttg ctagaaatgg agcaataact
     2701 atatttagta ctgagtcaat tgcaaaaaat ggtgatatat catcaatagt acctatggta
     2761 tctcatgtag accacactga acatgatgta atggtaattg taacagaaca aggatatgct
     2821 gatttaagag gtcttgcacc tagagaaaga gctataaaaa taatagaaaa ttgtgcccat
     2881 ccagattata aagaacaact tagagattat ttaaatagag cttgtaaaag tggagcaaaa
     2941 caaacacctc acatattgga tgaagcttta tcatggcata gtaaatttat gagtacaggt
     3001 acaatgaaaa aggctgaaac ttttaaaagt gcattataaa atatttaata aattggaggt
     3061 agattttaaa tgggaaaagc agtggaaaat tttgaagatt taagtaagga atacattaat
     3121 ggttatattg agagagccag aaaagctcaa agagagtttg aatgttatac tcaagaacaa
     3181 gtagataaaa tagtaaaaat agttgggaaa gtggtgtatt ataatgctga atatttagct
     3241 aaacttgctg tagaagagac tggaatggga gtatatgaag ataaggtagc taaaaataaa
     3301 agcaaagcaa aagttatata taacaattta aaagataaaa aatcagttgg tataattgat
     3361 atagatagag aaactggaat aacaaagata gctaaaccgg ttggagtagt agcggcaata
     3421 actccttgta caaatccaat cgttacacct atgagcaatg caatgtttgc gcttaaggga
     3481 agaaatgcaa ttattatcac acctcatcat aaagcaattg gatgtagtac aaaaactgtt
     3541 gagatgatta acgaagaatt agaaaaaata ggagcaccag aaaatttaat acaaatactg
     3601 gaccaacaat caagagaaaa cacaagaaat ttaatttcat cagcagatgt agtaattgcc
     3661 actggcggaa tgggaatggt aaaagctgca tactcaagtg gaaaaccagc acttggtgtg
     3721 ggagcaggaa atgttcaatg tattatagat agagatgtag atattaaaga agcagtacct
     3781 aaaatcatag caggaagaat ttttgataat gggatcattt gttcaggcga gcaatcagta
     3841 atagtagcag aagaaatgtt tgataagata atggatgaat ttaaaaataa caaaggtttt
     3901 atagttagag ataaagcaca aaaagaagct ttcagaaatg ctatgtttgt aaataaatct
     3961 atgaataaag atgcagtagg tcaatcagtt catacaatcg caaaaattgc aggtgttgaa
     4021 ataccagagg atacaaaaat aatagtaata gaagctgatg gaccaggaga agaggatatt
     4081 attgcaaaag aaaaaatgtg tccagttata tctgcatata aatataaaag ttttgaagaa
     4141 ggtgtagcta ttgcaaaagc aaatttaaat gtagaaggaa aagggcatag tgtatctata
     4201 cattcaaata cagttaagaa tatagaatat gcaggagaaa atatagaagt atcaagattt
     4261 gttattaatc aatgttgtgc tactagtgct ggaggaagtt tctttaatgg tcttgcacct
     4321 actaatactc taggttgtgg ttcttgggga aataacagta tctctgaaaa tcttgattat
     4381 aagcatctaa ttaatatttc tagaattgct tattatatgc cagaaaatga agttcctaca
     4441 gatgaagaac tttggggata aaatttagac aaaaaatatt cattctaaat taaaataaga
     4501 atatatttta atttagaatg aatttaagac ataaattaaa tttaaattag tctattagac
     4561 caaatttaaa atattaagag acatatagaa gaaggaagta ttataattta aaataaataa
     4621 aaaattctat aaaagagaag gagtggtttt attatggcat taatgacagg agctcaatat
     4681 attgaaagtt tgagaaaatt aaatactaag gtttatatgt ttggtgaaga ggttaagaat
     4741 tgggttgacc atcctatgat tagaccatct ataaattgtg tagcagcaac ttatgactta
     4801 gctcatgacc ctgaatatgc agatttaatg acagttactt caaatatcac aggtgaaaaa
     4861 ataaatagat ttggtcatct tcatcaaagt actgatgatt tgataaaaaa agtaaaaatg
     4921 caaagactat gtggtcaaaa aacagcttct tgtttccaaa gatgtgttgg tatggatgca
     4981 tttaatgcag tatattcaac aacatttgaa tgtgataaag cccatggaac taattatcat
     5041 gataattttg taaaatactt aacttatata caagaaaacg atttagtagt tgatggagct
     5101 atgactgacc ctaaaggaga tagaagttta tcacctagtg ctcaacctga cccagatatg
     5161 tttcttcata tagtagaaag aagagaagat gggataattg taagaggtgc aaaggcacat
     5221 caaactggtt caataaattc acatgagcac cttataatgc ctactataag catgactgaa
     5281 gcagataaag actacgctgt atcatttgca gttccttcag atgctgaagg agtatttatg
     5341 atttatggaa gacaatcttg tgacactaga aaattagaag aaggtgcgga tgttgattta
     5401 ggaaataagg agtttggagg tcaggaagct ttagtagtgt ttgataatgt atttgttcca
     5461 aatgatagaa ttttcttatg tggagaatgg gatttctctg gtatgttagt agagagattt
     5521 gcaggatatc atagacaaag ttatggtgga tgtaaagtag gagtaggtga tgtaataata
     5581 ggagcagcag ccttagcagc tgattataat ggagcaaaca aagcttcaca tataaaagat
     5641 aaactaatag aaatgactca ccttaatgaa agcttatatt gctgtggtat agcatgttca
     5701 tcagaaggtc acaagacaga agctggaaac tatcaaatag atttacttct tgcaaatgta
     5761 tgtaaacaaa atgtaactag atttccttat gaaatagtaa gacttgcaga agatatagct
     5821 ggagggctta tggttactat gccttcagaa aaagacttta aatcagacct taaagttgga
     5881 acaagtggaa tgactattgg cgaagtatgt aacaagtatt ttaaagcttc ttcagtagct
     5941 tcaacagaag aaagaatgag aatattaaga tttttagaaa atatatgtct tggttcatct
     6001 gctgttggtt atagaactga gtcaatgcac ggggcaggtt caccacaagc tcaaagaata
     6061 atgatttcaa gacaaggaaa cataaatcaa aagaaagaat tagctaagac aattgcagga
     6121 ataaaaaaag aagaagcttt aaatttataa aaagttgata tataaaggga aattatatat
     6181 taatgtttat taattaatga aaaaatatgg agtataagag ataattataa aattatggtg
     6241 gtttttagct aagtaaagaa attttttata aggagaattt acacatgacc tgtggagtta
     6301 gattttgtgg cggctgtaac cctagatacg aaagagggaa ggctcttgca ataatcaaag
     6361 agcacttcaa tggtagagta gattttagta tagcacaaga gaacttggag tatgatttgc
     6421 tacttataat tggaggatgc gcaactctat gcgcatccta tcaacaatat aaagtgaaaa
     6481 atgaatgtgt taagatgtgg gattttagcc atatagaaag agttataaat gtgattgaat
     6541 cagcaatttg tgaaacttaa aaaagctaaa tggggggatt tcattgagtt ggcgagaatt
     6601 gtatcaaagt aagttatgta gtgctacaga agctgtaaaa cagattaaaa acggagatac
     6661 tgtagtattt gcacattgtg taggtgaacc tcctgcacta gtagaggcta tgattgaaaa
     6721 tgctgaacaa tataaagatg ttgagattaa acatatggta agcttgggta gtggtggata
     6781 tactgctaag ggaatggaag ctcattttag agtaaatcca atgtttgtaa gtggaaatgt
     6841 aagaaaggca attgaaaacg gagatggtga ttttacgcct acattcttcc atgaagtacc
     6901 aaagttgctt agagaaaaaa gattaaaatg tgatgttgtt ttagcacagg taactccacc
     6961 tgatgaacac ggatattgta gcttagggac atcagttgat tatacttatg aagctattaa
     7021 aactgctaga acagtaattg ttcaagtgaa tgaccagttt cctagaactt atggtgaggt
     7081 agtccatgta tcagattttg actatatagt ggaaaaatca caacctttat atgaattaga
     7141 acctgcaaag attggagaag tagaagaagc aattggtaaa aactgtgctt cattaattga
     7201 agatggttct actttgcaac tagggattgg tgggatacca gatgcagtta tgttattttt
     7261 aacagataaa aaggatttag gaatccattc agaaatgatt tcagatggga ctttggctct
     7321 ttatgaaaaa ggtgttataa atggtaaata taaaaatttt gataaagaga aaatgacagt
     7381 tacgttctta atgggtacta aaaaattata tgactttgta aataataacc ctgcggtaga
     7441 ggtaaaacct gtagactatg taaatcatcc agcaattata atgaaacaac ataagatggt
     7501 ttccataaat tctgctatac aagttgattt gatgggacag gtagttgcag aggctatggg
     7561 acttagacaa tttagtggtg ttggaggtca agttgacttt atacgtggag tgtctatggg
     7621 agaagatgga aaagcaatta tagctatgcc ttcaataact acaaaaaaag atggtacagt
     7681 aatttcaaaa attgtatcta ttgtggatga aggtgcacct ataacaacat caagaaatga
     7741 tgttgactat attgtaacag aatatggtat agcagaatta aaaggaaaat ctcttagaga
     7801 aagagctaga aatttaataa atatagctca tccaagtgta agagaaagtc tagcaataga
     7861 gtttgagaag agatttaagg aaaaatatta ataatagaga ggtgttaata atggaagcac
     7921 ttagagtagt tccaaagata ttttattttg atacatttaa agaatttaat gaagaattta
     7981 aaataggaaa aaatgattta gtaattacta atgagtttat atatgagcca tatatgaaac
     8041 ctcttggaat agatacaaat ttaatttttc aagaaaagtt tggaacaggt gaaccatctg
     8101 atgaaatgat agattccatg acaaaggaaa tgaagaaata caattttgat agaattattg
     8161 cgtttggagg aggaacaata gttgatatat gtaagatatt agcgcttgat gttccagaaa
     8221 agtctattga tttatttgaa ggagaagtac cacctaaaaa aataaaagag ttagtagtag
     8281 ttcctacaac atgtggtaca ggtagtgaag taacaaatgt agctattgca gaattaaaat
     8341 ctaaacatac taaaaagggg cttgcagtag aagaaacata tgcagactat gcagtgctaa
     8401 ttccagagac agtaaaaggt ttaccttata aattctttgt tacaagctct gtggatgctc
     8461 ttatacatgc tattgaatct tatctttctc caaaagcaag tccatttaca gaaatgtatt
     8521 ctctgcaagc aataaaaatg attatggatg ggtataaaaa gatagttgat aaaggagaag
     8581 aagagagatt taatcatctt agagactttg tccttgcatc aaattatgca ggaattgctt
     8641 ttggaaatgc tggttgtgca gcagttcatg cactatctta ttcaataggt ggagctttcc
     8701 atgttgcaca tggtgaagca aattatcagt tctttactga agtatttaag atgtattcta
     8761 gaaaaaaacc taatggaaaa attataaaat gtacaaaaat tttagcagat gcccttgaat
     8821 gtgaccctaa ttgtgatgtt tatggagaat tagaaaagtt tttaaacaag ttaatagcta
     8881 aaaaagcttt gagagaatat ggaatggtgg aagctcagat agatgaattt acagatagta
     8941 caatagcaaa tcaacaacga ttacttgcta ataattatgt agaacttaat agagaggaaa
     9001 taagagagat atttgcaaat ctttattaat aaaatttttt attta
//
LOCUS       DBGJFK010000109         8955 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.115, whole genome shotgun sequence.
ACCESSION   DBGJFK010000109 DBGJFK010000000
VERSION     DBGJFK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8955
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.115"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(79..603)
                     /locus_tag="ACOIAP_003392"
     CDS             complement(79..603)
                     /locus_tag="ACOIAP_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HGZ2640264.1"
                     /translation="MKSIVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFFKKNYKELQKKNLVVFGVGAAPYDDEVIKRLREVNFKDE
                     LNKVPCFYCRGAWDETKMSFLDYTLCSFFKKSIAKKERQGLKPVEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            complement(652..1149)
                     /locus_tag="ACOIAP_003393"
     CDS             complement(652..1149)
                     /locus_tag="ACOIAP_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGZ2640265.1"
                     /translation="MNVETLMKKFMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKGRVEEYSKKVRGIQEKVLQLLFKDFTEKEVEQLFFGIMKLSAGIENVKNYVEN
                     NDIEE"
     gene            complement(1382..2659)
                     /gene="hflX"
                     /locus_tag="ACOIAP_003394"
     CDS             complement(1382..2659)
                     /gene="hflX"
                     /locus_tag="ACOIAP_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGZ2640266.1"
                     /translation="MDMAKKGITAGLNINNKSEDFNELMIELGNLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEELLNLIKKESIEVVVFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLVGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITFLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIILANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKNHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DEILDSIDKEGLFVSVKKDINIDKMIKCICDSIFKDYVRCKLLIPYDKGHVVSYFNEN
                     ASVISTEYREDGVILDVECSNIEYNKYKKYVLE"
     gene            complement(3388..5220)
                     /locus_tag="ACOIAP_003395"
     CDS             complement(3388..5220)
                     /locus_tag="ACOIAP_003395"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640267.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILMFLLCLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISEKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAILILPISMFVISRIVKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEDQIVENAVSIDGLKGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYNMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(5213..7459)
                     /locus_tag="ACOIAP_003396"
     CDS             complement(5213..7459)
                     /locus_tag="ACOIAP_003396"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640268.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELDKITLFMDKSSKDKVLDNYTLLNEKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNIIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFEGMPESMITQSSVSYVKSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMVSMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEEQEFKVDKKGLVEFRNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKEATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(7527..7988)
                     /locus_tag="ACOIAP_003397"
     CDS             complement(7527..7988)
                     /locus_tag="ACOIAP_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGZ2640269.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNRVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEEEKYF"
     gene            complement(8293..8859)
                     /locus_tag="ACOIAP_003398"
     CDS             complement(8293..8859)
                     /locus_tag="ACOIAP_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGZ2640270.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT         2898 a         1620 c          882 g         3555 t
ORIGIN      
        1 tattgtttta taaataatgt ctaataaatt tctatggaat ttaactttag ataataaata
       61 attataaata tatacctctt aaagttctct tatataatcg agtattggag ttaaattttc
      121 tttattacac caatcaaatg cttctccaga caataaaggt gcttctactg gtttaagacc
      181 ttgacgttct ttttttgcta tagatttttt aaaaaaacta caaagagtat aatctagaaa
      241 agacattttt gtctcatccc atgccccacg acaataaaag caaggaactt tgtttaattc
      301 atccttaaag tttacttctc ttaatctctt tattacttca tcatcatatg gagcagctcc
      361 tacaccaaat actactagat tttttttctg taattcttta taattttttt taaagaaaga
      421 aattcctgct atgttacaag cataaagacc tcctcctaaa ataatcgtat catacttcat
      481 aaccttttct atattaatat tcttagtttc aaaaatatca caagacaata attctgaaag
      541 ccacttagca tatttttttg ttgaaccata tttactctta taaatcacta ctatactttt
      601 catataaatt atctcctttc tgatgtcata caaagttgat tcgacacttg cttattcttc
      661 aatgtcatta ttttctacat aatttttcac attttcaatt cctgcactta atttcataat
      721 tccaaaaaat aactgttcca cttctttctc tgtaaaatct ttaaataaaa gctgtaatac
      781 tttttcttga atacccctta cttttttaga atactcttcc actctacctt ttgtcacaag
      841 acagatagct cgtgaatctt tttcattttg ctcaatttgt ataaaaccct tcttttctaa
      901 agcaatagct agttttttta cattttgtct tgagcacccc attaattctc caagtttagt
      961 taatgtaaga gtttcatcta cagagtccgc aatagctaaa agtaaccatt gtttcatagt
     1021 taattctggg tctaatttat cacatgtagt ttgaagttta ttttgcatta caaatatact
     1081 tgcaaatata gcttgttttc tactatcatc atctaccata aattttttca ttaaagtttc
     1141 tacattcatt attatacact tctctttatc ttagatttta attttttgat aactttaaat
     1201 agtaactagt tactttatat tatagtaatt ggttactatt atgtcaacaa atttattttt
     1261 atcataaatg gtaaaacggc atagcttgtg gctataccgt ttcataaaat catattttac
     1321 aatcaattta taattaatta taaattaaat atattttaag ctataataat tttttcaaaa
     1381 tttactctaa aacatacttt ttatacttat tatattctat attgctacat tctacatcta
     1441 aaataactcc atcttctcta tattctgtac ttataacgct cgcattttcg ttaaagtaag
     1501 aaactacatg ccctttatca tatggaatta aaagtttaca tcttacataa tctttaaata
     1561 tactatcaca aatacatttt atcattttat ctatatttat atctttttta actgaaacaa
     1621 ataaaccttc tttatcgata ctatctaaaa tttcatctaa tacttctaca tctattaaat
     1681 caattttatt atacacatgt atcataggta taccatctgc accgatttgt tttaaagtat
     1741 cttctgtcac tttaatatga tttttatagc ttggatttga aatatcaata acatgtagca
     1801 gtacatctgc ctcacatgct tcttctaatg ttgacctaaa tgcttttact aaatcatgtg
     1861 gtaaattact tacaaaccca acagtatcag ataataaaaa ttctttgtta tttgcaagaa
     1921 ttatatttct aacagaagtt tcaagtgtag caaataacat gtttttctca aatactttct
     1981 tttcttcaga gtttttaaat atatctacta atttgttcat tattgaagat ttaccagcat
     2041 ttgtataccc aactaaagct acatttggaa gatttgattt tcttctcata cttctttgag
     2101 tttctctttg gaattttaag tcatctaact ccctatttag aaatgttatc ttttcttcta
     2161 ttcttctacg gtcaagttct aattttttct caccagagcc tctattttta gtaccaactc
     2221 caccactttg acgccctaaa ttttcatttg aacctacaag tctaggtaac atatatttta
     2281 aacttgctac ttctacttga agtttagctt ctctagtttt tgccctttgt gcaaatatat
     2341 caagtatcaa tgctgttcta tctataattt cacaattgag cttttcttca agatttttta
     2401 gttgtgatgt agaaagttca ttgtaaaata caactacctc tatgctttct ttctttatta
     2461 agtttaataa ttcctcaact ttacctgtcc caatgtaaaa tgctctatta acctgctttg
     2521 cattttgagt tatactccca acaacatcaa tatcacatgc tgaacataag tttccaagtt
     2581 caatcattag ttcattaaag tcctcagatt tattatttat atttagtcct gctgttattc
     2641 cttttttcgc catatccata ttctccttat ctgctatttt ttatttaatc tatagcacaa
     2701 gattatggct ctataattaa attcatcaag aattttattt tttatcttat ccttaaatga
     2761 cacttattaa attataaatt ttaccattat aataaccata atcgtgcatt attttctcaa
     2821 tcttatataa aaaatcactt tcttacacct cctcctaaat atattatgca gttttttcaa
     2881 taaaaaaact ccttacaaat ctaagtaata caaaacaagc tacttatatc ataagaagga
     2941 ttaaagttct aaatatatat taaaaataca ttagtttaat taacttgtat gtaattatca
     3001 ttttatattt aaccctattc ttaaatttaa gtagttattt acatgattaa taaaagcaat
     3061 aaaaatatct acttcaatat aatcatcaac tattaaaatt aaattttatt tataataaaa
     3121 tttaaagaat ataattaaat atacattttg ataatcacct ccaacatttt ccttactaca
     3181 tattataata aaattaaaac gttgtaaaga cataaaattg tgtagatgtc tcaaaataaa
     3241 tagaatcctc ttttttattg ctaaaatgat aaaaatacat tttgtttcat acataaaaga
     3301 gtgccttatg aaccaaaaag ttcattttaa gacactctca tttattttat cttattaatt
     3361 aaacttctat gctaagatag ttttttgtta cattgcttca tcttcttcaa attgagaatt
     3421 gtaaagatta gcataaaatc cacctttctt tagaagttcc tcatgatttc cttgttcaac
     3481 tatatctcct tcattcatta caagaatcat atcagcatca cgtatagttg ataatctgtg
     3541 ggctataaca aaacttgttc taccttccat aagattatcc atagcctttt gaatcaatac
     3601 ttctgttcta gtatcaacag aacttgtagc ttcatctaat attaaaattt taggatcagc
     3661 taaaatagca cgagctatag tcaataattg tttttgacct tgagaaacat tacttgcttc
     3721 ttcatttaat ttcatattat atccatctgg taatgtctta ataaatctat gaacatgtgc
     3781 agatttagca gcctctataa cttcttcatc tgtagcattc aacttaccat atcttatatt
     3841 ttccataatt gaaccactaa ataaccatgt atcttgaaga accataccaa acatttctct
     3901 aagctcacta cgattaaaat ctttaatatt atgtccatca atcagtattg aaccgctatt
     3961 aacatcataa aatctcatta aaagtttaac tattgtagtt ttacctgctc ctgtaggtcc
     4021 aacaatagca actttttgac caggtttaac atttactgaa aaatcattta ttatagtctt
     4081 gtttgggtta tatccaaagt taacattttc aaaatcaatt ttacctttta aaccatctat
     4141 tgaaactgca ttttcaacaa tttggtcttc ttcttcctct tctaaaaact caaatactct
     4201 ttcagaagct gctgctgttg attgcaataa attggcaacc tgtgcaatct gagtcattgg
     4261 ctgtgtaaag tttcttacat attgtataaa tgattgtatg tcaccaacct caattgtttt
     4321 cttaattgca agccaacctc ctaagattga taccattaca tatcccaagt ttccaataaa
     4381 catcataagt ggttgcatta tacctgataa aaattgagac ttccatgctg aattatacag
     4441 gctatcattt aatttatcaa actcttcaat tacctcatct tcacgattaa atgctttcac
     4501 tattgtttga ccactataag tttcttcaac ttgaccattt acatttccta aatattcttg
     4561 ttgatatcta aagtattttt gtgatttctt tactattctt gaaattacaa acattgatat
     4621 tggtaatatt aaaattgcta ccaatgtcat aattccactt atagataaca tcattatcaa
     4681 aacacctatc atagttgtta ctgatgttat aagctgtgtc atactttgat ttaaactttg
     4741 atttaaagta tctatatcat tcgtaattct cgataatatt tcaccatgcg tcttagtatc
     4801 aaaatacttc attggcaatc tatccaattt ttctgaaatc tcttttctta aattatagga
     4861 tactttttga gaaattccac tcattataaa tccttgtata aaagagaaca gtgcacttat
     4921 taaataaagg caaagtaaaa acattaagat ttttccaatt gcattaaaat ctatacctac
     4981 atttcctcca gaaactttac tcactaatcc ttcaaatatc tttgtagttg ccttacctaa
     5041 aatttttgga cctactatag aaaacgacgc actaccaata gcaaatacaa ttactaaaat
     5101 tattgatatt ttaaatttag ataagtatgc aattagtttt ctcatagtcc ctttaaagtc
     5161 atttgctttt tgtcctgctc ccatagattt tcccatagga cctcttccca ttctactcat
     5221 tagctagctc ctcctttgaa agttgtgata aagctatttg ctcataaact tcgcaatttt
     5281 ttagaagctc tttatgtgtt cctattccaa ctatttctcc ctcatttaaa acaattatct
     5341 gttctgcatt taagatagta ctaattcttt gtgcaactat taaaactgta ctttcagcag
     5401 tttttgattt taaagcctta cgaagagctg catcagtttt taagtcaagt gctgaaaaac
     5461 tatcatcaaa tatataaact tctggatttt ttgctattgc ccttgcaata gaaagtcttt
     5521 gtttttgacc tccagataca tttgttccac cttgagaaat ttcagtttta aaagcttctg
     5581 gtttagaatc tataaattct gtagcttgag ctatttcagc tgctgttctc atttcttcat
     5641 ctgttgcttc ttttctacca tattttaaat tggattctat agtaccagaa aacaatactc
     5701 ccttttgagg tacatatcca attttttctc ttaaatcatg ctgagaaaca ttttttatat
     5761 taactccacc aagtaagatt tctccttcag taacatcaaa gaaacgagga attaaattta
     5821 taagagttga cttaccacta ccagtacttc ctataaaagc agttgtttct cctggctttg
     5881 ctgtaaaaga tatatttgtt aatataggtt cctctgcgtc tggatacatg aatgaaacat
     5941 ttctaaattc aacaagaccc tttttatcta ccttaaattc ttgttcctct gatttttctg
     6001 ggtcttttat gcttatatct gacactagta cttcatctat acgtgtagct gaaacggatg
     6061 ctcttggaag catgatagat accattgata tcattaagaa tgacattatt atttgcattg
     6121 tatattgtat aaatgccatc atatctccaa cttgcattgc tccagaatca acactatatg
     6181 cacctctcca aactataaga actgtgataa ggttcattat aagcatcata gccggcatca
     6241 tacatgtcat aactctattt acaaaaagat ttgttttagt taaattttta tttgctttat
     6301 caaatctttc ttcttcatgt ttttcagtac taaaagctct gataactgga ataccagtaa
     6361 ttatttcacg acttactaag tttaacttat ctacaagctt ttgaactagt ttaaacttag
     6421 gcataaccac tgagaataac actacaatta atgataaaat agcaactact gctactgcta
     6481 taatccatgc cattgaagta tttgtgttta aaacttttat tactccacct atagccatta
     6541 taggtgcata gaatactatt ctaagcaaca taaccatcaa catttgtatc tgttgaatat
     6601 catttgtact acgagtaatt aatgaagctg tagaaaattc attcatttca gtatttgaaa
     6661 atgacataac ttttctaaag actccacttc ttaaatttct acctacactt gctgctactc
     6721 ttgctgctaa aaatcctact gttattgtgg ctaccatact aaccattgct ataccaagca
     6781 ttttagcccc agtaaataat atataattat tttgagtttt ttctgtatca atacctattt
     6841 tctcatattc tgactttaca tatgatactg aactttgtgt tatcatactc tctggcatac
     6901 cttcaaagcc tttgctcatc tctttagtca atgtgtctaa ctgttccttt ggcattgctg
     6961 atagcaattt aaatatatca acatctccac tttgagtagc ttgtggtgga agtttactca
     7021 ttaactgagc tttcatagct tttacctctt tactatcgcc ctcaagccct gatactatca
     7081 aaatagcctt accaaaaata atatttaaat catctatagt atctttgtct ttagtattta
     7141 actcataaag agattcatct tttagacctg ggtacttatc tttatactta acataatcct
     7201 tttcattcaa caaagtataa ttatctagta ctttgtcctt actgctttta tccataaata
     7261 aagtaatttt atctaattca ctctctctaa tcacagatgg aacagagttt tctactccac
     7321 cttgttgtat acctacattt actatattgg atgtgtattc tggtaaagaa aggtcacata
     7381 ccgcttgaat taccaatagg cagactatta ttactattga taatgccgat ttctttaaat
     7441 atttaattaa tttaaacata catttcttcc cttctgtaat attaattagt ctaataacat
     7501 taaattgaaa aatattattt taaactttaa aaatattttt cttcttcatg cttatgacat
     7561 cctgctttta aattatctcg tacttgcatt agaagtcttc taagtactat tttttcttct
     7621 tcactaaatc ctaaaaaaaa ctctctttcc aattccttgt taaattcttc aactctatta
     7681 catatttcta aacctttgtc tgtcaaaaaa attctagata ctctttggtc cttttcatct
     7741 tgttttcttt ccacaagtcc agctttttcc atcctcttta tcataactgt agttgtagat
     7801 gcttttactt tccttttatc tgctaattct ttttgacttt gcccatcttt catctttaaa
     7861 gaaaaaagta tttgaggttg accatgatat aagcctaatt tatcaaaata aaaatgagtt
     7921 cttataaaat atattcgcat taattgcaag aaaacatcat ttaatttttc ttcagaattg
     7981 ctattcatac ttgccctcct tattttttat attacttagt cggctaagca ttattttact
     8041 atactgcatg cattttttca atatatttat aaaaaattca tataaatttc atttattaaa
     8101 tattttcaca tcatatagtt atacttttaa taaataatag taagattttt aattagtcag
     8161 ctacgtatat tttttattgc aaagcttaaa ataaaccttt tcatatattt tcaaataaaa
     8221 aagttgtccc aaaataaatt ttgaaacaac atcttactca acagtatctt gattatataa
     8281 cactataata ctctatttat cttcatatcc atttacaaca acatctaatt ttccagtttc
     8341 tggtgatata attagaccat gtacaataat accatctgga attaaaggat gcccttttat
     8401 taaatcaata ctatctttta cagattcttc tgcagaatcg aatccatgta accattgttt
     8461 tgtatcaatt ccagcactac gaagtgtaag tattacatca ttagatattc ctctatctaa
     8521 aattttacca agtaacttat ccgtatcaac attacacata ccacatccat gatgccctac
     8581 aaccatgacc tcatctacat caaattcgta aattgcaact aaaacacttc tcataatact
     8641 tccaaaagga tgcattatag tagctcctgc attttttatt agtttcacat ctccattttt
     8701 taaattcata gccttaggca aaagctcagt taatcttgta tccatacaag ataagactac
     8761 tattttttta tttggatgtt ttgatgtcac atattgttca tattctttgt tctctacaaa
     8821 tgatttatta tactctaata tctcctcaag ttttctcata tgtaatatca ccctctttaa
     8881 aaattttttt attattatat cactattaaa ctacaatata tacatatata atttaattta
     8941 tatttattaa ataat
//
LOCUS       DBGJFK010000110         8768 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.116, whole genome shotgun sequence.
ACCESSION   DBGJFK010000110 DBGJFK010000000
VERSION     DBGJFK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8768
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.116"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            162..1274
                     /locus_tag="ACOIAP_003399"
     CDS             162..1274
                     /locus_tag="ACOIAP_003399"
                     /inference="COORDINATES: protein motif:HMM:NF024572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGZ2640271.1"
                     /translation="MLTSEEFLIFFERYNQLIRLINKGMYKEAIQGFKLITEQYCDLI
                     EPYELLALLYDKEEEYIKFDECLEVLNTIDKENYLLNQENNTLDMYNSTNIQTKSNVK
                     VDDYKNEFLHKSSNNHKIDDYKNVTKEKSSSINQKNSDSNKKKSIKKNKYLYIAIVLG
                     ILLIGQGIYSSYKMNNLTDKISKNNETKNEESTDSSLAKKENNIEENEDMNKTSNIDK
                     SNKNINKEDIKSKKNTVENEDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVAD
                     IGENKGNTSEATYQVAILSEKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYY
                     NNGDLKSSKLTLKKLVNKVPNSMYNNSKVKEILKEE"
     gene            1390..3327
                     /gene="htpG"
                     /locus_tag="ACOIAP_003400"
     CDS             1390..3327
                     /gene="htpG"
                     /locus_tag="ACOIAP_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HGZ2640272.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKIIVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDTRNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEVVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFHVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKETVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKVTLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            3706..4836
                     /locus_tag="ACOIAP_003401"
     CDS             3706..4836
                     /locus_tag="ACOIAP_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGZ2640273.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKATGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKSSIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPIADVQAIYG
                     IELISENLVKVYNNVNDLEAWEKITLASTIGGMTIGTAGTALSHGMEHPVSGLRDVMH
                     GKGLAALTPVIIESSWDSDTERFGNISKILGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEEIKEMYRKSL"
     gene            5064..6086
                     /gene="splB"
                     /locus_tag="ACOIAP_003402"
     CDS             5064..6086
                     /gene="splB"
                     /locus_tag="ACOIAP_003402"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006290 - pyrimidine dimer repair [Evidence
                     IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HGZ2640274.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKNIYNKFKDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GKEEKGRFRFVTKYSDVDSLLDAKHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIRSIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFHKEINGVFKNS
                     LIKYII"
     gene            6253..7164
                     /locus_tag="ACOIAP_003403"
     CDS             6253..7164
                     /locus_tag="ACOIAP_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGZ2640275.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLAKASEYLAEHKNRILDVALKFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVTRKTLSNPRTFVGIEMEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VELGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTAD
                     FAIEMYYPTTPEVAYLEHWIVPIPIEQ"
     gene            7179..7595
                     /locus_tag="ACOIAP_003404"
     CDS             7179..7595
                     /locus_tag="ACOIAP_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HGZ2640276.1"
                     /translation="MNWQDTFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVNESNRVEVDLFINTCCDYIK
                     QIYNEVKFFNGGKWLMIQVDSLLVLNDMLELIKFRI"
     gene            complement(7695..8087)
                     /locus_tag="ACOIAP_003405"
     CDS             complement(7695..8087)
                     /locus_tag="ACOIAP_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGZ2640277.1"
                     /translation="MGINSEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESDGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNKCGLNCKECRKTK"
     gene            8228..8623
                     /locus_tag="ACOIAP_003406"
     CDS             8228..8623
                     /locus_tag="ACOIAP_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HGZ2640278.1"
                     /translation="MKALEFLNKAGVYYLATADENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT         3573 a          892 c         1503 g         2800 t
ORIGIN      
        1 ggggatggcc tgtggagaat taataagaca tattttagta cgcaaaattc tgtgaagcag
       61 gaaccctgtg actttagtca tgggaggttc aggaggctgt agaaagtttc tataagagtt
      121 cactttgtga aaaaactgct ctgtgtgaaa agtatataaa catgcttaca tctgaggagt
      181 ttttaatttt ctttgaaagg tacaatcaac ttataaggtt aataaacaag ggtatgtata
      241 aagaagctat acaagggttt aaacttataa ctgagcaata ctgtgattta atagaacctt
      301 atgagttact tgccttactg tatgacaagg aagaagaata tataaaattt gatgaatgtt
      361 tagaagtatt gaatactatt gataaggaaa actatttatt aaatcaagaa aataatacac
      421 tagatatgta taatagtact aatatacaaa ctaaaagtaa tgtaaaagta gatgattata
      481 agaatgagtt tttacataaa agtagtaata accataaaat tgatgattat aagaatgtaa
      541 ctaaagaaaa gagttcaagc ataaaccaga aaaattcaga ttctaataag aaaaaaagta
      601 ttaaaaaaaa taaataccta tatatagcaa tagtattagg aatattatta ataggacaag
      661 gtatatatag ttcttataag atgaataatt taactgataa aatatctaaa aataatgaaa
      721 ctaaaaatga agagtcaaca gattctagtt tggctaagaa agaaaacaat atagaagaaa
      781 atgaagatat gaataagact tctaatatcg ataagagtaa taaaaatatt aataaagagg
      841 atataaaatc taaaaaaaat actgtagaga atgaagatga taaagattct gacttattta
      901 cagaggatga attgatgtct aaggcaaata ctttaaaatc agaaaagaaa actaaatctt
      961 ctatacaact atataagaaa gttgcagata taggtgaaaa taaaggaaat acatctgaag
     1021 caacttatca agttgctatt cttagtgaaa agttaaaaga ctataaaact gctgaagaat
     1081 attataaaat gtatgtggaa aattactcag aaaaagatgc ttattttgat gaatcttatt
     1141 ataacttagg tatgatgtac tataacaatg gtgatttaaa aagttctaaa ttgacattaa
     1201 agaagttggt taataaggtg ccaaatagta tgtataataa ttcaaaagta aaagaaattt
     1261 taaaagaaga atagctaaat tagataagaa aaataaatta ttttatttta aaataatatg
     1321 attataatat attgacatac cattttaaaa aatttaaaat attaattata aaatgaggag
     1381 ggataaaaaa tggagtttga aaaagggagt atttcaattc atacagaaaa tatttttcct
     1441 ataattaaaa aatggttata ttctgataaa gacatattta taagagagct tataagtaat
     1501 ggatgtgatg cagtaagtaa acacaaaaga cttgtatcat taggagaaat atcagagaat
     1561 aagtcatcag attacaaaat tatagtatct gtaaataaag gagaaggtac gcttaaattt
     1621 attgacaatg gaattggtat gactgaagaa gaaataaaaa aatacataaa tcaagttgct
     1681 ttttcaggtg ctgaagattt ctttaataaa tataaggata agatggaaga gtcaaatgac
     1741 ataataggtc attttggatt aggattttat tctgcattta tggtgtctaa aaaggtacaa
     1801 atagatacac tttcatatac agaaggagca actcctgtaa gatggatatc tgaaggtggt
     1861 acagaatacg aaatatctga atcagatact agaaatgata gaggaactac tataacacta
     1921 tttattgatg atgatagtaa agagttttta gatgaattta ctgtaagagg gataataaat
     1981 aaatactgtt ctttcttacc agtagaaata tatttagaag atgttgaaag attagaaaga
     2041 gaagctaagg aagcagaaga aaaagctaaa aaacaaaagg aagatggaaa agaagaggtt
     2101 gtagatgcaa aagtaattga gcctttaaac gacactaatc cgctatggtt aaaatctcca
     2161 aaagattgta ctgatgagga atataaagag ttttatagaa aggtattcca tgtatttgat
     2221 gagcctttat tttggataca tttaaatgta gattatcctt tcaacttaaa gggtatactt
     2281 tacttcccta aattaaaaaa tgagtttgag ttgactgaag gaaaagtaaa attatacaac
     2341 aatcaagtgt ttgtggctga caacataaaa gaagttatac cagaattttt acttttatta
     2401 aaaggtgtta tagactgccc agacttacca ttaaatgtat caagaagttt cttacaaaat
     2461 gacagagacg taagtaaaat ttctaaacat ataattaaaa aagtagctga taagttaaaa
     2521 tctctttgta aaaatgaaag agaagaatat aataaatttt gggatgatat acaaatattt
     2581 attaaatacg gttgcttaaa agatgaaagt ttctatgaga aggtaaaaga atgtatatta
     2641 tttaaaacta ttgatgatga gtatataaca ttacaagatt atctagaaaa atgtaaggac
     2701 aaacacgaaa ataaggtatt ttatgtaagt gataaggagc aacaatctca atacattaaa
     2761 ttatttaaag aatacgactt aagtgctgtt gttttaaact catcaataga tactcatttt
     2821 atttcattta tggaatataa agaaaatgga gttaagttta atagaataga tgcagacctt
     2881 tctgatgtat taaaagataa aaatgaaaat aaagatagtg aagaaaacaa agaagagata
     2941 gctaagatag aaggtctgtt taaagaaact gtcggagaaa gagtaaagaa ttattctgta
     3001 gaaggattga aaaatgaaga cactccagct atggtgttag tatcagaaca atctattaga
     3061 atggcagaaa tgcaatcaag atttgctgga atggatttag gaatgaattt tgaggaagaa
     3121 aaaactcttg ttataaatga gaacagtcca ataatcaaaa aattggtttc tcttaaagat
     3181 gatgaggaaa agaaagataa ggttacgctt atttgtaatc agatagcaga tttagcttta
     3241 ctttctaata aagaattaaa gccagacgag ttagattcat ttgtccaaag aagtaataaa
     3301 cttatgagtt tgttgataga attataaggt tgaatttgaa tacattgaag taaatttata
     3361 aaaagtattc aatatcaatg ataataaaga ggtgtctcaa agtgaacttt ttagttcatg
     3421 aggcactttt tttatgtgaa attaaatgta ttttaatcgt ttcaataatg aaaaagaaat
     3481 ttatctctat ttttagacag actatttttt atatttgatt aatttttaaa tatttaagta
     3541 ggttctaata aaaaactcta tttagttaaa tatagttaac ttgatatata ataaaataat
     3601 acatataatt aagtaaaaga ttgtttttta gtttatgttt aaatacataa ttaaattttg
     3661 ttaaaaaata aaattattaa taaaatagaa ataggaggta ttagcatgaa ttttaattat
     3721 aatttgccag taaatatctt atttgggaga ggcagaatta atgatgtggg aaaagaagta
     3781 tccaaatatg gcaaaaaagt attgatagta acaggtaaaa atagtacaaa aaaaactgga
     3841 ttacttgata aaacaataga tttactaaaa gactctaaaa tagaatatga agtttttgat
     3901 agagtagagc aaaatcctct tataactact atatattcag gagtagaaat tataaaagca
     3961 actggatgtg attgtgtttt agggcttggt ggaggaagta ttatggatgc tgctaagagt
     4021 atagcttttt cctataaaaa cccaggagat ttaaatgatt atatatttgg aattagacaa
     4081 ggtgaagaag ctttacctat aatcttagtt ccaactacat caggcacagg tagtgaagga
     4141 aattgttttg cagtacttac aaattcagaa actaaagata aaaaatctat aaagaagaat
     4201 agtatgtatg caaaatcatc aataattgac ccagaactta tggttacaat gccaaagcat
     4261 ataattgcat cagttggatt tgatgcactt gctcataata tggaagcata tctttctaat
     4321 ggaagaaacc ctattgcaga tgtacaagct atttatggga ttgaacttat atcagaaaac
     4381 ctagtaaagg tatataataa tgttaatgat ttagaagcat gggaaaaaat aacacttgca
     4441 agtactattg gaggaatgac gattggtaca gcgggaacag ccttgtcaca tggtatggag
     4501 catcctgtaa gtggtcttag agatgtaatg catggaaaag gacttgcagc tttgactcct
     4561 gttattatag aaagttcatg ggatagtgat actgaaagat ttgggaatat ttctaaaata
     4621 ttaggaggaa cttgtgcaga agattgttca gatgcaatta gaaattttct taaaaaaata
     4681 gatttggata taaaactaag tgatttaggt attgaaaaat cagatataga ttggttaact
     4741 gataattgta tgaaaatatc agttgcaaat attaagagac atccaaagta ctttaataag
     4801 gaagaaataa aagaaatgta ccgtaaatct ctataatctg attttacata tttaacttta
     4861 aataaaaatt ataaattaat aataaaaaat ttataattaa tcaatagcaa aaaaattgtg
     4921 tataggaatt agatacacaa taaacttgtc ttaagctttt attttacttt ctaataaata
     4981 aaggagttta aaaaagggaa gattaattaa gtaatatttt ataaaagtct tcgatttaaa
     5041 aactttaagt agaggtgaaa taaatgttta atcccaaaag aataatattc gaaaaaggaa
     5101 ctttagacac tgatgtgggt aaaaatatat acaataaatt taaagataat aaagatgtag
     5161 agataattaa tatatcatca aatagaatta aagaacatat tccaggtgaa aatctatatg
     5221 aacaatatag aagtgggaag cagactatgg tggttgggat tagaaaaagt ctgaagtttc
     5281 aaacatgtaa accttctgct aattaccaac taccacttgt cagtggatgt atgggaagat
     5341 gtgaatattg ctatttaaat acacaattag gtgataaacc ttttataagg gtatttgtaa
     5401 atgtagatga aatactagaa cagacaaaaa aatatattga agatagaaag ccacaggtaa
     5461 ccatatttga aggagcggct acatcagacc cagttccagt ggagccatat actaattcct
     5521 tgaagaaaac aatagagttt tttggaaaag aagaaaaagg aagatttaga tttgttacta
     5581 aatacagtga tgtagatagc ttattagatg ccaaacataa taatcataca gaaatacgat
     5641 ttagtatcaa tactcctaga attataaacg aacatgagca ttatacagca tctgcaaata
     5701 aaagaataga gtcagctgta aaacttgcta gggctggcta tcagattggt tttataatag
     5761 cacctgtgtt tttatatgaa ggttggaagg aagaatataa aaatcttatt agaagtataa
     5821 aagaagcttt accaaaggat tttgataaaa aaattatatt tgaagttata tctcatagat
     5881 atacaactaa agcaaaaaat agaatattag agatttatcc agatacacta ttaccaatgg
     5941 aaaatgaaga tagaaagttt aaatacggtc aatttggata tggtaagtac gtgtacgata
     6001 aagaacaatt agatgatatg aaagagttct ttcataagga aataaatgga gtatttaaaa
     6061 atagtttaat aaaatatata atatagcaaa tcttatctaa agatttgcta tattttattt
     6121 ttataataaa gtgatgagtt ttagtactat aatatgagaa aattaaaaag ggcactatct
     6181 atcaagaaca ttttttctag ttttgatact ataaaggata agagtaacaa aaatatcagg
     6241 aggagttata atatgcatgc atgggagtct attcaaatta cgttggattt aatagaagca
     6301 aacttatcag aagaaatatc aattaatgaa ttagcaaata aagcaaactt atcaccattt
     6361 tactatcaga gactatttaa aagattggta aataagactg taatggagta tataaagctt
     6421 cgtcgtcttg caaaagcttc tgaatactta gcagaacata agaatcgtat acttgatgta
     6481 gctttaaaat ttggatttgc tagccatgag acatttacac gttcctttaa aaaagcatat
     6541 ggattaactc cagaaaaata tagagcaaat ccagtaaaac tcaatcactt tattaagcca
     6601 gaattaattt taaattatgc tatggttgat gaaggtgttc cactgattgc agatgatata
     6661 gtgattgaag tcactcgtaa gacattgagt aatccaagga cgtttgttgg aatagaaatg
     6721 gaagtaccta tttgccagtt ggtgggcggt gaaacaactg gtattgcaat agtagaggaa
     6781 ttatggatga aacttggaag tcaaagacat aatataccaa atcaaattcc aggtggaaat
     6841 gaatttgctg ctctttatat gggaaatgca aaagaaggaa attgtatgta tatggcaggt
     6901 gtagaggtag aattagggac atcagtagaa ggatatagta cttttgagtt accagctaaa
     6961 gaatatttag tatgtggatt tgaggcagaa aactttaatg agttagttaa ttcagctgtt
     7021 tttaaagcgg ataaatttat ggaaagatgg atgaagaagc ataatttaac aactgctgat
     7081 tttgcaattg agatgtatta ccccactaca cctgaagtag catatctgga gcattggatt
     7141 gttccaattc ctattgaaca atagaaagga tgatgaatat gaattggcaa gatacgtttt
     7201 ttcaagatac taaacctaca tttgagcaaa ttaatgaatt tattaataat ccattatggg
     7261 acaagttaaa taaaactttg gtttctactt ataatgtaga acctaagctt gaatacagta
     7321 aatgttcaat gcaaagaggc tggaatgtaa aatacaaaaa aagaggtaaa tcactatgta
     7381 ctttatatcc acaagaaggt tattttaaag ctttggttat tgtaaatgaa agcaatagag
     7441 tagaggttga tttatttatt aatacttgtt gtgattatat caaacaaata tataatgaag
     7501 taaaattttt taatggtggt aagtggttaa tgattcaagt agatagtttg ttggtattaa
     7561 acgatatgct tgaactaatt aaatttagaa tataaaatat aaaacaggat gaatatataa
     7621 gtcatcctgt ttttatattc aatcagataa attaatatat agactatagt ataaataatt
     7681 tagcaaattt aaatttactt tgtttttcta cattccttgc aattaagtcc acatttattt
     7741 ttttcttgca tattggtagc accccaatta gcaaattgtt gtaaaatagg tacaatactt
     7801 ttgcctttac ttgttagtgt atattcaacc tttggaggaa tttcattata ttgtttacga
     7861 tgaacaatac catcagactc taaatctttt agtgattgag ctagcatagt gtttgtaatt
     7921 ccatctaatt ttctttttat gctactatat ctaatgggat tttcaactgc taacatacat
     7981 ataataggta atttccactt accaccaaca atatctaatg cataacgaat tggacaggtt
     8041 aattcttcaa catttttagt tatatttttt tcactattta tacccatttt aattactcct
     8101 tagttataat agtatctttt ttatacttta taagaaaaaa ctgcatactt gttttttctg
     8161 tattttatat taaaattata tcaaaggata atccttaata caagtattta aaaggggtgt
     8221 aagaattatg aaagcattag aatttttgaa caaggcagga gtttattatt tagcaacagc
     8281 tgatgagaac aatcaagcac atgtgcgtcc tttaggattt gttatggaat acaatggtaa
     8341 acttacattt tgtacatcta atcaaaagga tatgtttaag caacttattt ttaatccaaa
     8401 ggttgagctt tgttgtatag accaaaacct taatactcta cgtattttag gtgaagcagt
     8461 atttgttaca tcaaaagaaa cacaagctaa agcacttgaa ataatgccaa gtttaggtca
     8521 gatgtactct gtaggagatg gtaagtttga aatattctct attgataagg caaaagttag
     8581 ttgttgttca atgagtggta aaaagattga tgtagaactt taattataat tgaatcgata
     8641 cacatagtga aaattgaaaa aacgttatca ctgaaatatt gaagatttaa ttaaaatgca
     8701 ataaaatgtt tttaaataat gaatggataa aaatttttag ttattagatt tgtatttcaa
     8761 taatgata
//
LOCUS       DBGJFK010000111         8634 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.117, whole genome shotgun sequence.
ACCESSION   DBGJFK010000111 DBGJFK010000000
VERSION     DBGJFK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8634
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.117"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(235..843)
                     /locus_tag="ACOIAP_003407"
     CDS             complement(235..843)
                     /locus_tag="ACOIAP_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HGZ2640279.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISN
                     FYYDDKGKKVFSKDKLDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(952..3690)
                     /locus_tag="ACOIAP_003408"
     CDS             complement(952..3690)
                     /locus_tag="ACOIAP_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2640280.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNISLYTVSINMYRIILLW
                     IFGYSIVYISNFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFRDINWNMIIVLINVCISLFNLLY
                     LLNKLDSNIEHYKLIKDLTYFIFFTTIIGFVAIYKINIVDSNRFIGVIYLLLCNHTYY
                     VYVYSLRNRVVYPYYELDSINKKLSKKSEQLGKINLVIEKDMIIQRKLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMDNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNGKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRHINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCTSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLVE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNSIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIEKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKIIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3838..4629)
                     /locus_tag="ACOIAP_003409"
     CDS             complement(3838..4629)
                     /locus_tag="ACOIAP_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2640281.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKALDEIKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIQIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4666..5322)
                     /locus_tag="ACOIAP_003410"
     CDS             complement(4666..5322)
                     /locus_tag="ACOIAP_003410"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGZ2640282.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSAINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALVILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5315..6280)
                     /locus_tag="ACOIAP_003411"
     CDS             complement(5315..6280)
                     /locus_tag="ACOIAP_003411"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640283.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGNVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERRTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6386..6492)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6658..7203)
                     /locus_tag="ACOIAP_003412"
     CDS             complement(6658..7203)
                     /locus_tag="ACOIAP_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HGZ2640284.1"
                     /translation="MHCSTPLLKELFNIVMNESTIKIEYSSKQKNSIRTIVPIGLYAM
                     NGLWYCPAYCIKSESIKEFRADRIVKILSIENLSNKKYNVLSSIHDYFKNMEVGTDYR
                     IKINLADEGVKHCETEFLLARGLKILSKGGYIDMYIPKSTLNWVAEYFLTFGKNATII
                     EPIELKHLILFNIFLIMMFYS"
     gene            7350..7679
                     /locus_tag="ACOIAP_003413"
     CDS             7350..7679
                     /locus_tag="ACOIAP_003413"
                     /inference="COORDINATES: protein motif:HMM:NF039682.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6194 family protein"
                     /protein_id="HGZ2640285.1"
                     /translation="MIKYCLSNLDDVVLMNSCWERAVYCNPNGVLKRGVYVLTIKEKD
                     SNNDKDSLVNRSNVYRVNIRLKKETFTEMFGYIPKRPGVGQIVDMDFDFTKLDIVMPH
                     PIYSWMG"
     gene            complement(7958..8557)
                     /locus_tag="ACOIAP_003414"
     CDS             complement(7958..8557)
                     /locus_tag="ACOIAP_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640286.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTRNNEKPNENAGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLITEGERLVKDIDKRIEKLDKVSDEDMKKSQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2799 a         1434 c          812 g         3589 t
ORIGIN      
        1 ctatttatct atataaattt tataattttt aataagatac acaaaaaaat taatttttat
       61 agctcatttc gccaaaatat atctttcttt atatcagtaa aataattata aatttattaa
      121 aaatgtttgt aattctacaa agttattttt atcaaactaa aaattctata aaaaaataag
      181 atacatatcc ataaaatacc ttcctataga tacatatctt acctatataa aaacttattc
      241 tatataaaaa cgccataaaa aatcttttgc ttcttctgca taatctatat ttatacgttt
      301 actagttttt atatctaatt tatctttact aaatactttc tttcctttat catcataata
      361 aaaattactt atatataatt cttcacccat tatactctta ctatttagac ttctatctat
      421 ttttaatgct ttgcaaagtt ttcctggtcc attagtaata ttttttactt gatatttact
      481 caactcagtg taagctttgt tgtatctatt catagatatc tcatccaaag aagttatagg
      541 ctctacccct cttattaata cacactctgg aacattttct atatttgcag ataaatttaa
      601 gcaattatac ataccataga ttaaataaac atatatatgt ccaccatcta aatataacgg
      661 cttcgttcta tctgtttttt tattgccata tacatgtgct cctttatcat ttacacccat
      721 atatgcttcc gtctctatga ttttggtaac aattacttta ttttcatatt tccttattag
      781 gtatttacct aatattgatt ttgctaaatc aattccattt ttcctaaaaa aatccttttc
      841 caaaatttca cctcataaaa tttatttgca acgcatcaaa tacaactaaa gtaataaata
      901 aaattaactc ttattaatgt gatatatata aacaataaat tccgacattt attatttata
      961 tatatcaaaa aattctatct caaacttttc aatattatca ttgtaatttg aattatcata
     1021 tacttcttca acaacctctt taattgggaa tataattttt acattagttc cttctcctac
     1081 cttgctatct atataaatct ttccattttg aatttcaatc aacgattttg tgaggcataa
     1141 ccctatacca cttccaaatt catttgatat gccactgttt tcaatttgtt taaatcgatt
     1201 aaatatatca tttaattttt ctttctctat acccactcca gtatctttta taattatctc
     1261 tactgtttcg tcttttttat atatacctac aaggatttct cctccttcta aagtaaattt
     1321 tatagaattt gataatatat ttagtattat tctttctata gattctgggt caagccctac
     1381 cataacagtt tcttcatctg tatcaaaaat taaatctatt cctttagact tagcataact
     1441 actaatagat gtaactattc tttctgttat gtcaataata tcaaaattaa ccgctttaat
     1501 cttatatatg tctgacttaa cttgagaaat atttattata ttatctatta atctcaataa
     1561 tctaaacata ttttgttttg ttatttttat gtgttctttt aatatatcct gaaaatcaat
     1621 tatttttcct tttttataaa gattttcaac aagttgaact gaactgtata tattatttaa
     1681 aggtgtctta agttcatgag atatattagc ataaaactcc atcttcattt ggtcatactg
     1741 tctttgtttt attaatgctt tcttaagtct ttcagactct ctttgcacac ttaaatcttt
     1801 aataattctc actctacttc ttttttgtcc aaagtataat gttcttgata tcatttttac
     1861 ttctttgatg tgattatttt catttactat atggatactc ttctctcttt ctcctatatt
     1921 taaattgttt atgtattttt ttactaatat atttctatat ttttgtgttg taactcctag
     1981 tacatcacta gaaattccaa acaactctct gaaagctcta tttgtatata atactcttga
     2041 tgtacttaaa tcttcaagaa aaatagcctc tggtataaca tccagtaatt tttcgtatat
     2101 tattttttgt tcatttactg ttctaagaat atttatctct ttagttatat ctctaaatgt
     2161 aagcaattta aagagtttat tatctgacca atagtctcca actctaactt cttcaacatg
     2221 ctcttcacct tctgaatcag acatcacaaa attaactata cagtttgctg tgtcattgta
     2281 acttactatt tcagctttct tttcttgtgt taaatttaat cttttaaatt ccctattgtc
     2341 aaagaaatct atgttaaaag tttcaaaata ttgttctaat gtcatatcga ctaaatcact
     2401 tgaagtacat ttaaaactct tttcatattt tttatttata cttattacct tattcttctt
     2461 tataccgcct tcagcacttc ttacaagtat aggagatgga atatttagta taatgttttc
     2521 atagtcttta tttatatgtc ttatttcttc atctattttg atttcatttg taatatcatt
     2581 taaacttatt aagtaattgc tttcatcttt attattactt aaacttaaca aataaatttt
     2641 accatttaac tctactaatt tatcaattat acttatatcg ttatcaaatt tcttcaattt
     2701 ttcagcaacc ttttcatctt cctttataaa agttaatatt ttataataat tatccatatc
     2761 ctttgaaaat tcatctttaa atttattatt tgtgtaactt atattaaagt catagtctgt
     2821 tactatccat acatttggta ttgtgtccag agcttgtcta agtaattctt ttctctggtc
     2881 tatatagttt tttaattttc tttgtataat catatccttt tctattacta aatttatctt
     2941 tcctaattgc tctgactttt tacttaattt tttatttatt gaatcaagtt cgtaatatgg
     3001 atacactacc ctatttctaa gactatatac atatacataa taagtatggt tacataataa
     3061 taaatatatt actcctataa atctatttga atctactata ttaatcttat aaattgctac
     3121 aaagcctata atagttgtaa aaaaaataaa atatgttaaa tcttttatta acttatagtg
     3181 ctcaatgtta ctatcaagct tattcaacaa atatagtaaa ttaaacaaag atatacaaac
     3241 attaattaat acaataatca tattccagtt aatatctcta aaaatatttc ttataaagta
     3301 atctaatatc acaaaagcac tataaaaaat taatattggg cttattctta gtttttttac
     3361 tttagaaata gttaagtata taaaagtaga catattaatt atgcttaaat tgagcaacac
     3421 aatttggaat ttttgaattt ttaaatttac tactcctaaa atacttacaa aaactaatac
     3481 aagacaccct actttcaata tatttataaa ttcatctgtt ttaaagttac ttatataaac
     3541 tatagaatac ccaaatatcc aaagtaaaat tattctatac atatttatag aaactgtata
     3601 caaacttata tttaaaagtg caataaccaa aaataaccca ttagctagta tatagacctt
     3661 attcttactt aaagttccct tagattccat attccccacc acttcttcat ttttatatag
     3721 ttttacctat aaatatgtta ccacaattct tccaaaaaat ttgtcacttt ctagttataa
     3781 aaaaaaatga gtaaatattt ttaattttac tcattttgta gattttgtat attcaattta
     3841 aaaagctgga actatacttc ctttgtattc gtcttgtata aattttttaa cttctttact
     3901 attcatagcc tctgacaaag ccttaatctt atcactatct ttattatttt ctctacaagc
     3961 tattatattt acatatggag aatcacttga ttctattact attgcatcct tagtaggatt
     4021 taaattagct gttaaagcat aattagaatt tattactgct ccatcaacat cttttaatac
     4081 tgttggtaat tgctctgcat tcatttcttt tatttgtata tttttagggt ttttagttat
     4141 atctttttta gttataagct cgccatcttt tacctctatc aatttatttt ttgctaataa
     4201 tttaagtgct ctagctccat tagttgcatc atttggcaca gctataacag ctccatcttt
     4261 tatttcatct aatgctttaa ctttttctga atagaatccc attggctcta tatgaacttt
     4321 agatgtataa gtaagtttat atcctttctc cttcacagtt tcctctaaaa atggaatatg
     4381 ttgaaagaag ttagcatcta aagacccttc atctaaagct gtatttggaa gtacataatc
     4441 atcaaatatt tttacttcta aatcgtatcc tttttctttt aacaacggtt ttgctacttc
     4501 caatatcttt gcatgtggat ttgatgaagc tcctactagt atttttttat cctctttgtt
     4561 tgagcaacct actgctgata ttgctattgc tgacaccaat gctactgata ataatttctt
     4621 taatttcatt ttttactccc cctctttaaa atgtttataa ttaatttatt ttagtttctt
     4681 ataagccaga tttcctactc cctggattat ctgaactaat attacaagtg ctattacagt
     4741 atataccatt actgctgtat caaatctttg atatccataa ataagtgcta tattacctag
     4801 tcctccagcc cctactgcac ctgccatagc tgtataacca agtatagata ttattgataa
     4861 tgtaattcca gatactattg aaggcatagc ttcctttatc ataactttaa atactatttg
     4921 tctttttgta gcaccaaaag attttgctgc ttctatcaat cctttatcaa cttcatttaa
     4981 tgagctttct ataatcctag cgataaatgg tgctgcccca atagttatag gcactattgc
     5041 agcagtttcc cctatgcttg ttccaacgat taatctagtt attggaatca ttgcaactat
     5101 aagtatcata aatgggaaac ttctaaatat atttactata aatcctaatg cactatttat
     5161 tgcgctattt ggttttaatc catctggttt tgtaactact aatatgattg ccaatataaa
     5221 tcctaatatt gttgccacta tagttggtac tataaccata tacaaagttt gtaacaatgc
     5281 atttggaaat agtgttgtta aaaagtcaat taaactattc atttatcatt tcctcccatc
     5341 ttatgccctt actagtcaga tattgtttta cttgttcgcc acttttatcc gaaatattta
     5401 taataagtga acctaaaata tcatctttaa attgttctaa tttcccaaat attatagaca
     5461 catctatatt tagttctctt gccatagtcg taataatagc ttcattagaa atatctttag
     5521 ggaatagtat ctttatattt gttccttttg gtaatattat actttcttct cctattaatt
     5581 ttctaagacc tttagtattt cttaagaata tttcttctgt atctcctacc tctaatactt
     5641 ctccattttc cattattgct actcttccac aaatctgctt tatgacctcc atttgatggg
     5701 ttacaactat tattgttatt cccaattttt tatttatatc ttcaagcaat gaaagaattg
     5761 attttgtagt atttgggtct aatgctgaag ttgcttcatc acaaagaagt acctgtggat
     5821 ttagtgctaa agctctagca attgcaactc tttgtttttg accaccactt agatttctag
     5881 gtttatcatt tttcttttca gatattccaa ccacttctaa taactctaaa actctttttt
     5941 taatttctgc ctttgaatat ccaaaacact ctaatggcaa tgctacatta tcaaatacag
     6001 ttcttctttc aagcaatgaa aaatgttgaa aaatcattcc taactctttt cttaaatctc
     6061 tcatttgctt ttcattcaat gattttactt ctttgtcaga aacaagtaca ttaccttctt
     6121 ggtattcctc taatccgttt atacatctaa gtagtgttga tttacctgca ccactatgac
     6181 ctattattcc aaaaatttct ccagattcta tttcaatact cacatcttta agcacttgaa
     6241 tctttccata atacttatta acatttttta tgctaatcat aaaatttcct cccatatatt
     6301 ctgctcagtt tttatgttta tcctagctta tgtattacaa caaaataaaa gcccgagtat
     6361 aaactcaggc ttagaaagct atttatactc atctatcaac tatattagtt gcaggattta
     6421 gcaccaatgt atacaaaata tactggttgc cgggtttcaa agggccagtc cctccaccac
     6481 tcttgataag acgttattta atttaattct attatcattt gttgctatgt tatatataat
     6541 atattcatta atagtatttg tcaataaatt tatttaaatt ttttattttt tattattgtt
     6601 aattaactat ttttaattag ttttctagct cctaacactt tatattttaa tgtctatcta
     6661 actatagaac atcattataa gaaatatgtt aaatagtatc aaatgtttaa gttctatagg
     6721 ctctattatt gtagcatttt tcccaaaggt taaaaaatat tcagccaccc aattaagtgt
     6781 agattttggt atatacatat ctatgtatcc acctttagac aaaattttca atcctcttgc
     6841 caacaaaaat tctgtttcac aatgttttac tccctcatct gccaaattaa ttttaatacg
     6901 ataatctgtg cctacttcca tattcttaaa ataatcatgt atagaagata aaacattata
     6961 tttcttattt gataagtttt ctatactcaa aatcttcaca attctgtctg cacgaaattc
     7021 cttaatagat tctgatttta tgcagtaagc tggacaatac caaagtccat tcatggcata
     7081 caaaccaata gggacaatgg tacgtatact atttttttgc tttgatgaat attcaatttt
     7141 aattgtagat tcattcatta ctatattaaa caattctttc aataatggtg ttgaacaatg
     7201 catatctggt gtccaaaaaa caaatttacg cctcatattc tcaatattat attaaatatc
     7261 atttggtata caatttaatt ttttttaaaa cagaaatagt ttcttgctca aacggcaaat
     7321 cactataaga tactattaag gctgatgata ttatcaaata ttgtctatca aacttagatg
     7381 atgttgtact aatgaatagt tgttgggaac gagcagttta ctgcaatcct aatggtgttt
     7441 taaaacgagg agtatatgtt cttaccatta aagaaaaaga cagtaataat gataaagatt
     7501 cgttggttaa tcgttcaaat gtataccgtg taaatatacg attaaaaaaa gaaactttta
     7561 ctgaaatgtt tggatacatt ccaaagcgtc caggtgtagg tcaaatagtt gatatggatt
     7621 ttgattttac aaaattggat atagtcatgc cacatcctat ctactcatgg atgggatgaa
     7681 tatgcatcct aagccctact gaaaagacat ttaagaacct taaaacttta ataggagaat
     7741 cttacaattt tgcaaaagaa aaattcaaaa agagaaaaaa caagtaaaaa catatgaaaa
     7801 taacctctaa ataaattata ataaaaatat taaggttaca agataaaaaa ttaatatctt
     7861 aataatatac aaaaaagcga agccaaaaaa tgtattattt ataaggcttc gctatatctc
     7921 aaataattta tttcaaattt taaaactatt tattctatta tttcttatta tttcctgtta
     7981 ttcctaatct atcattcata tcttttatca tttttctaaa accactacct atatcatttc
     8041 caacatcttc agttccatga actaatttta taaagtcatt ttgacttttt ttcatatctt
     8101 catcagatac tttatctaat ttttctattc tcttatctat atcttttact aatctttccc
     8161 cttcagtgat taggtcatca ttcattttct ttaactctgt atcttctgtt ttaccatctt
     8221 ttttaagaga tgttacaaat gattgtattt tatctctact atctttatat gcagccttta
     8281 catcacttag atatttttca tttcctggat attctttgtc tttaaactga ttatttatac
     8341 tttctggagt atcataaata gagtatctat ttagacctgc tatataatca ttatagcttg
     8401 ttgaataata attcatatat ccttcattat tatttacaga ttcattagga ttttttcctg
     8461 cattttcatt tggtttttca ttatttctag tacatgcagt tatacctata gctaatacta
     8521 atgctaatcc tacaaataaa gttcttttta atttcatttt tattaccctc ctagatgttt
     8581 tatactacaa aaaattttaa taattttctt tcttaattta gtatttctaa attt
//
LOCUS       DBGJFK010000112         8450 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.118, whole genome shotgun sequence.
ACCESSION   DBGJFK010000112 DBGJFK010000000
VERSION     DBGJFK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8450
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.118"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..2323)
                     /gene="secA"
                     /locus_tag="ACOIAP_003415"
     CDS             complement(<1..2323)
                     /gene="secA"
                     /locus_tag="ACOIAP_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGZ2640287.1"
                     /translation="MSVLDTILDKADEQEIKKLNLIVDKIEALEEKIQNLSDDELKEM
                     TNVFRNRLNNGETLDDILMEAFAVVREVSKRKLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYESLGMTVGVIIANQD
                     QNIRKQQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGDGDEDLKLYELANSFIKTIKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEINNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPVIRADLHDKVFKTEEEKYNAVVEEIIRIHKTRQPILVGTVSVEKSEKLSRMLKK
                     QGIKHQVLNAKQHDKEAEIISKAGKLDAITIATNMAGRGTDISLGAGDREEEQQVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NNEDIQEDIQKMVKDIIQEAGENYLVGRKRDYYGYFKYLYSTFMPADTLLIPGVDKKS
                     VQEIVDSTYEISKRVYDLKKMMLGIDKVSELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATV"
     gene            complement(2523..4703)
                     /gene="slpA"
                     /locus_tag="ACOIAP_003416"
     CDS             complement(2523..4703)
                     /gene="slpA"
                     /locus_tag="ACOIAP_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HGZ2640288.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPVFAADEQVKYQNTYTVVQSKYEK
                     ALKDMQKGITDKKIKSIAISYEGKPVTTITVADMDTKGKTSTKEELASALLKTTVNDK
                     LDNLGDGDYVDFDITYVGDADRLTAGDLNTFAKGIADSTEKKIPAAKGSNYGVAKTNS
                     GTGKLTTDTEAVISTSIEGKVEGNNLTISLKDAPSKVGVIGANNDTLADVTFADDAKL
                     TVSVGDPKIDLAKSFIFDTKTGKLGGIVEKENDATEHAYVRVINAKEQTIDLDASSYK
                     SAEDLAKAYAFDVNELKTLYTEIEAYQKDSNNKTDKVQIVDGKYQTILYAEGKRLTTK
                     SATQASKLADENSPLKLVIKADKLKDLKDYVEDLRNANNGYSNTVTVAGDDRIETAIE
                     LSSKYYNNSDEDNAITEDAVNNVVLVGSQAIVDGLVASPLASEKKAPLLLTSKDKLDS
                     NVKSEIKRVMNLKTTTGINNSKKVYLAGGVNSISKEVENELKDMGLKVTRLSGDDRYA
                     TSLEIADEIGLDDDKAFVVGGTGLADAMSIAPVASQLNEKGDATPIVVVDGKAKELSS
                     AAEDFLDDSQVDIIGGKNSVSKDMEDAIDDATGKSPNRVSGDDRQETNAEVLKESDYF
                     PDGAVNYFVAKDGSTKEDQLVDALAAAPVAANFGRTYNIKDNDSSGTVSPAPIILATD
                     SLSSDQNVAISKALPSGKSGDNLVQVGKGIANSVITKIKDLLDM"
     gene            complement(4916..6505)
                     /locus_tag="ACOIAP_003417"
     CDS             complement(4916..6505)
                     /locus_tag="ACOIAP_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HGZ2640289.1"
                     /translation="MKVNKRILSIGLTISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGAVKAPILLSQRNNIPPDTEKMLKDVKKA
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGDDRIETSYLIAKEIASIKSINKVFITNGY
                     TGEADAMSASSVASRDGAPIILTDGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNILAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSINVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYNLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILSNGEVYATQEFLNK"
     gene            complement(6723..8324)
                     /locus_tag="ACOIAP_003418"
     CDS             complement(6723..8324)
                     /locus_tag="ACOIAP_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HGZ2640290.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADRQTYETVILVNTEKSLADGLSASGLSGVTKAPILFTQKNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELNSKNIEVKRIGGEDRLKTSYLMAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKGIPFDVKNVQSYCIGSEEIMSNSLVKNTNSVR
                     IEGTDRFETNKNVIDYFFKNADGFYVSDGYQLVDAIAAAPLTKDSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVVQQCTNASKSNGQPPTITIGNIEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTEKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKETLLVSSKLEDMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKKVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
BASE COUNT         2414 a         1639 c          908 g         3489 t
ORIGIN      
        1 gcactgttgc ttcccttata tttttattta aagcttcaaa catgtcatat ccttctaaag
       61 catattcctt aaacgggtct ttttgagcat aagatttaag acctatatac tgtcttaact
      121 gttccatagc atctatatgg tctatccagt attggtcaac tacttttaaa agtactgtct
      181 tttccaactc tgaaacctta tcaataccaa gcatcatctt ttttaaatca taaactcttt
      241 ttgaaatttc ataagtacta tcaactattt cttgaacact ttttttatct actccaggta
      301 ttaatagtgt atctgctggc ataaatgtac tatatagata tttaaaatat ccataataat
      361 ctctttttct tccaactaaa taattttctc ctgcttcttg tatgatatct ttaaccattt
      421 tttgaatatc ttcttgaatg tcttcattat ttaaaacttt atttctttca ttatatataa
      481 cttttctttg ttcattaata gtatcatcat atttaaggac attttttctt atttcaaaat
      541 ttttaccttc tacacctttt tgagctcttt ctatagctct tgtaagtgct ttactttcaa
      601 tagcagtatt ttcctttgaa cttgttctct tcataagttt ctctatagtt tttccaccat
      661 aaagctttat tacatcatct tcaagactta caaagaatct tgatgtacct gggtctcctt
      721 gacgaccaga acgtcctcta agctgattat caattcttct tgattcgtgt ctttctgttc
      781 ctataacata aagcccacct aaatttttaa cttgttgttc ttcttctcta tctcctgcac
      841 ctagagaaat atccgttcct ctacctgcca tatttgtagc aatcgttata gcatctaatt
      901 taccagcttt agaaattatc tccgcctctt tatcatgttg ttttgcattt aagacttgat
      961 gcttaatacc ttgtttttta agcattctag ataatttttc agatttttca acagaaactg
     1021 ttcctacaag tattggttgt ctagtcttat gtatccttat tatttcttct acaacagcat
     1081 tatacttttc ttcttctgtc ttaaatacct tatcatgtaa atcagctcta atcactggtt
     1141 tattagttgg tatttgaaca acatttagtt tatagattga ctcaaattcc ccttcttctg
     1201 tctttgcagt accagtcata ccagaaagtt tttcatatag tctgaagaaa ttttgataag
     1261 tcacagtagc catagtttta gattcattat ttatctcaac accttctttt gcttctatag
     1321 cttggtgaag tccatctgta tatcttctac catccattac tcttcctgta aattcgtcaa
     1381 ctatcattac ttctccattt gagataacat agtcaacatc tttttccata agcttatgac
     1441 ctcttaaagc ttgatttatg tgatgatata attctatatt ctttatatca gtaaggtttg
     1501 ttataccaaa aaatgactca gctttgctta taccacttgc tgttaatgct atagttttat
     1561 cttttctatc catctcaaag tcttcttctt taatagtttt tataaagcta tttgccaatt
     1621 cataaagttt taaatcttca tctccatctc ctgcaataat aagcggagtt ctagcttcat
     1681 ctattaatat tgagtctacc tcatctacta tggcaaagtt tagttctctt tgtaccttat
     1741 gagataaatc tggaaccata ttatctctta aataatcaaa tccaaattca ctatttgtac
     1801 cataagttat atcacattta tactgttgtt ttcttatatt ttggtcttgg ttagctataa
     1861 ttactcctac tgtcatacca agagattcat aaactggtct cataagttct ttatcacgtt
     1921 ctgccaggta atcatttact gtgattacat gtacaccctt acctgtaaga gcatttagat
     1981 atactggtgc tacttcaact aacgttttac cttcacctgt tttcatctca gcgattttac
     2041 cttgatgtat tactatccca ccaattaact gtactctata ttgacgcatt cctaattttc
     2101 tttttgatac ttctcttaca actgcaaaag cttccattaa tatgtcatct aaagtttctc
     2161 cattatttaa tctattccta aatacattag tcatttcttt caattcatca tcagataagt
     2221 tttgtatttt ttcttccaaa gcctctattt tatctactat taaattcaac ttcttaattt
     2281 cttgttcatc tgctttatca agtattgtat ctaaaactga catgtgtttc ttacctcctt
     2341 ttttatcata caactattat tataccttaa aaatgtggaa tagtagacaa cttttttatt
     2401 tatagtataa taatcatact tgaatgaatt acatctctta atcagttagg tattttttaa
     2461 aatacaaagt aaaaaagatt cctaaaatag gaatcttttt tactttgtat tttaaattta
     2521 tactacatat ctaataagtc ttttatctta gtgattactg agtttgctat acccttacca
     2581 acttgtacta aattatctcc tgattttcca gaaggtaatg ctttacttat tgcaacattt
     2641 tgatctgaag ataatgaatc agttgctaat atgattggtg ctggagaaac tgttccagaa
     2701 ctatcattat cttttatatt ataagttctt ccaaagttgg ctgctactgg tgctgctgct
     2761 aatgcatcaa ctaattggtc ttcttttgta gatccatctt tagcaacaaa gtaatttact
     2821 gcaccatctg ggaaataatc agattctttt aatacttctg cattagtttc ttgtctatca
     2881 tctccactaa ctctatttgg agattttcct gtagcatcat ctatagcatc ttccatgtct
     2941 ttagaaacgc tatttttacc acctattata tcaacttgtg aatcatctaa gaaatcttca
     3001 gctgctgagc ttaattcttt agcttttcca tcaactacaa ctattggtgt agcatcacct
     3061 ttttcattta attgagaagc aactggagct atactcatag catctgcaag tcctgttcca
     3121 cctactacga atgctttatc atcatctaaa cctatttcat cagctatttc taatgaagta
     3181 gcatatctat catctcctga taatcttgtt actttaagtc ccatatcttt taattcattt
     3241 tcaacttctt tagatataga attaactcca ccagctaggt aaactttctt agaattgttt
     3301 attcctgttg tagtttttaa attcataact cttttaattt cagattttac atttgaatct
     3361 aatttatctt ttgaagttaa taataaagga gctttcttct ctgaagctaa aggtgatgca
     3421 acaagtccat caactattgc ttgagatcca actaatacaa cattattaac agcatcttct
     3481 gttatagcat tgtcttcatc tgaattatta tagtatttac tacttaattc tattgcagtt
     3541 tctattctat catcacctgc tacagtaaca gtatttgagt aaccattatt agcatttctt
     3601 aaatcttcaa cataatcctt taaatctttt aatttatctg cttttataac taacttaagt
     3661 ggtgagtttt catctgctaa tttagaagct tgagttgctg atttagtagt taatctcttt
     3721 ccttcagcat aaagtattgt ttgatattta ccatcaacta tttgaacttt atcagtttta
     3781 ttattactat ctttttgata tgcttctatt tcagtgtaaa gagtcttaag ctcatttaca
     3841 tcaaatgcat aagctttagc taaatcttca gctgatttat atgaactagc atctaaatct
     3901 attgtttgtt ctttagcatt tattactctt acatatgcat gttcagttgc atcattttct
     3961 ttttctacta ttccacctaa tttaccagtt ttagtatcaa aaataaatga ttttgctaaa
     4021 tctatttttg gatctccaac tgatacagtt aattttgcat catctgcaaa tgtaacatct
     4081 gcaagtgtat cattattagc acctattaca ccaactttac ttggagcatc cttaagactt
     4141 attgtaagat tatttccctc aactttacct tctattgaag tagatataac tgcctctgta
     4201 tctgtagtaa gttttccagt tccagaattt gttttagcaa ctccatagtt agaaccttta
     4261 gcagcaggaa ttttcttttc agtactatct gctatacctt ttgcaaaagt attaagatcc
     4321 cctgcagtaa gtctatcagc atcaccaaca taagttatat caaaatctac ataatctcca
     4381 tcacccaaat tatctaactt atcattaaca gtagtcttta ataaagcact tgctaattct
     4441 tcttttgttg aagtttttcc ttttgtatcc atatctgcaa cagtaatagt agtaactggc
     4501 ttaccttcat aagatattgc tattgatttt atctttttat ctgtaatccc cttttgcata
     4561 tcttttaaag ctttttcata tttactttgc actacagtat atgtgttttg gtatttaact
     4621 tgttcatctg ctgcaaatac tggtgcagcc gaacctacta ctgtaacagc agccatagcc
     4681 attgctaaat ttttcttatt catttcttaa attcctccca acattatatt aaaattacat
     4741 ctctttatta tgtacataga ataatcatcc atatattcct aatatttctc acatctctat
     4801 aataatccat tttaattctt tttgcaaggc atttttttga aattattatt tttcccaagt
     4861 atatgagttt ttataccctt aaatttcaat atttaataac ttaaaaaatt taattttact
     4921 tatttaaaaa ttcttgagta gcatacactt ctccattaga caatatatac agtccaaacc
     4981 cagtatatac aaaatcacta tttagcatat tttcattata tttatccgac tttttccaaa
     5041 ctgtaaatat tacatttgct acttctctag catcctttgt cgtataagta ctttttgtaa
     5101 caagtggtac aaaagctata ttctcttcac ttctcaaccc atatccagta aatacttcaa
     5161 cagatttctt accatctatt acatgtgaaa actggccttt atctgccatg tacttagacc
     5221 aggaattaga aagcccttct aagtttttag aaacttgtaa tggttcttta cctttttctt
     5281 ttctatatga atttaccaaa ttatacattt cactagaaac cattctttta aactcactac
     5341 tattcatatc attagtctta tattcaagta catttacttc tacatttatt gatgtagtct
     5401 ttccaccaat atcagtagct tttatagtaa ctttgtattt accaacctta tcagtattaa
     5461 tatttcctat aagctctggt gtcaaatcgt taccattgct atcctttgct aatatattaa
     5521 gtttacttat atcaaactta tccccttgat aaatatttaa atttccaaca gttattgttg
     5581 gtgcacttgc atccagtgat gatgcactta aacattgttc tagtgtcttt tcatctattc
     5641 ctcctaatgc tgtgatttta tcagcacttc taagcacaga cttatcacta tttccatcaa
     5701 ccaatacaat aggtgcattt ttagctatag aagaaccagc aactgcatct actaattggt
     5761 aacctttaga aagataaaat tcttttgctg aactataaaa atgttttata acttttttat
     5821 tagtctcaaa tctatcttct ccagctaatc taactgcatt agttttttta actaaatcat
     5881 tacttattat ctcctctgaa cccagagcat aacattgcac accttctttt ttctcaaatg
     5941 gaacattttt accatcagtt aaaattatag gtgcaccatc tcttgatgct actgatgacg
     6001 cactcatagc atctgcttca cctgtataac cattagttat aaaaacctta tttatagact
     6061 ttattgaagc tatctctttt gctataagat aacttgtttc tattctatca tcaccaccta
     6121 ttcttttaac ttctatccct ttttgcttta attcattttc aactgatttt cctattgaat
     6181 cttcagttcc tattatataa gccttcttta catcttttaa cattttttct gtgtctggtg
     6241 gtatattatt tctttgtgat aataatatag gtgctttaac tgctcctgct aatccacttg
     6301 cacttagtcc gtcagctagt gtattatctg tatttactaa tactacattt tcatacgttt
     6361 gcttctgtgc aattttggca gccgtctcat atctatcttt cccttgtatc ttttctatac
     6421 ttgaaagtgc attgatattt ggtgctcctg ccattattaa tgatattgtc aatcctatcg
     6481 ataatattct cttatttacc ttcatcgaac tcctcctact aattttttat ataattcagc
     6541 taatcataaa ttacatcccc agtagtgatt ccctcaaaat ttacaaacta ctaaaacaaa
     6601 aaacatctaa aataccataa cctataaagc aataacaaaa cagattacaa aaagtacttt
     6661 agatgtgatt ttgattttat aatatcagta aattaacaaa aaaacaacat ttatggaatt
     6721 ttttacaagc taccttcatt gccatttaaa aactcttgag tagcatgcac ttgaccatca
     6781 gataatatat aaagcccaaa tccagtacta tagaactcat cactaagcat atttgcatta
     6841 tactctggag acttcttcca cacctcaaat atagcctttg ccaaatcttt tgcatcttga
     6901 gttgtttgaa ccttcttaga atctatataa atatatgcta tattttcctc acttctcatt
     6961 ccaaactcag aaaatacttg tggagcattt ttaccatcta tataatgtgc aaatactttt
     7021 ttatccatca tatacttaga ccatgcattt gccatgtctt ctaacttact agacactaac
     7081 aaagtctctt tgcctttttc ttttctatag gaattgatta agttatacat ttctgtagat
     7141 accatttttt taaattctgg gctgttgtaa tcatgagatt tatcatccaa cacttttatt
     7201 tctactcttt tttctgtact ttttccccat tcatctgtag cttttaatgt caatatgtat
     7261 gtacctaccc tatttgtatc tataaaccca tcaacttcta ttggtaatac ctttccagta
     7321 ttatctttag ccactatatt taatttgcca gtgtcaaact tttcaccctt atatatctct
     7381 atatttccta ttgtaattgt tggaggttgt ccatttgact ttgatgcatt tgtacattgt
     7441 tgtactacct tctcatctat ttcacctaca gaagttatat tcttagctcc ttctaataca
     7501 gtcttatcac ttccatcatt tactagcacc attggagagt ctttagtaag tggtgcagct
     7561 gctattgcat ctactaattg gtatccatct gatacataga atccatctgc attcttaaaa
     7621 aagtagtcta ttacattttt attggtttca aatctgtcag ttccttctat tcttaccgag
     7681 tttgtatttt taactaatga gttactcatt atctcctctg aacctataca atatgactga
     7741 acatttttga catcaaaagg gatacccttt ccatctgtaa gtatgattgg agctccatct
     7801 ctagtagcta ctgatgatac actcattgcg tctgcttctc cactatatgc attagttaat
     7861 agtactttat ccactttctt tatagttgct atttctttag ccattaaata gcttgttttt
     7921 agcctatctt ctccaccaat tcttttgact tctatatttt tagaatttag ttccttttct
     7981 actgatttac ttatagtatc ttctgtacct attatgtatg cttttttgat attttttaaa
     8041 catctatttg tgtctgctgg tatcttattt ttttgtgtaa atagtattgg cgcttttgtt
     8101 acacctgata atccacttgc actcaatcca tctgcaagtg atttttctgt atttactaaa
     8161 attactgttt cataagtctg tctatcagct atctttgctg ctgtttcata tctatcttta
     8221 ccatatattt tttctactac tgatgatgca tttacacttt tgaagtttac taagattaat
     8281 gatactgcta gacctaatga taatattttt ttgttcattt tcatatcccc ctgatgattt
     8341 ttatatttta tatttacatt acgattattt tccatttatt ttttctttat tttccacata
     8401 ttatagagta tatatgatat taatatatcc agtctatata ttaatatttt
//
LOCUS       DBGJFK010000113         8410 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.119, whole genome shotgun sequence.
ACCESSION   DBGJFK010000113 DBGJFK010000000
VERSION     DBGJFK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.119"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(202..726)
                     /locus_tag="ACOIAP_003419"
     CDS             complement(202..726)
                     /locus_tag="ACOIAP_003419"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGZ2640291.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVKTDAADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(791..1543)
                     /locus_tag="ACOIAP_003420"
     CDS             complement(791..1543)
                     /locus_tag="ACOIAP_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HGZ2640292.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPENIKKIYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1574..2872)
                     /locus_tag="ACOIAP_003421"
     CDS             complement(1574..2872)
                     /locus_tag="ACOIAP_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HGZ2640293.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHTVESTKEILDKNRFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGLLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISIGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2889..5153)
                     /locus_tag="ACOIAP_003422"
     CDS             complement(2889..5153)
                     /locus_tag="ACOIAP_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HGZ2640294.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5407..6225)
                     /locus_tag="ACOIAP_003423"
     CDS             complement(5407..6225)
                     /locus_tag="ACOIAP_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGZ2640295.1"
                     /translation="MFKINNLTYQYEKNANALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEIFFKEEKLKYDKKSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGIDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHKNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6218..6916)
                     /gene="cbiQ"
                     /locus_tag="ACOIAP_003424"
     CDS             complement(6218..6916)
                     /gene="cbiQ"
                     /locus_tag="ACOIAP_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HGZ2640296.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLHSFEIFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6919..7203)
                     /locus_tag="ACOIAP_003425"
     CDS             complement(6919..7203)
                     /locus_tag="ACOIAP_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2640297.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7193..7945)
                     /locus_tag="ACOIAP_003426"
     CDS             complement(7193..7945)
                     /locus_tag="ACOIAP_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HGZ2640298.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANTFSMAIIGPIVSFLIFKALKKKDG
                     NNAMPVFLAAALGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8132..8324)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
BASE COUNT         2632 a         1515 c          914 g         3349 t
ORIGIN      
        1 ataagcaatc atagtaaaat ttttttaata gaggtttatt ttttagttaa aatcctacaa
       61 tatatagttt tctctaatac aaaaaaatta aaaagtgaaa tgtatttgtc taaaaacata
      121 acaacatttc actttattct cattattaag taatatattt ttaattttta tttataactc
      181 aatctagttt ttatataagt tttagttttt ttctacatct gaataatcta ttccaaaagt
      241 ttctacagta acagatttca taatttgtgg agtttgtggc ttatcagctg catctgtttt
      301 aactgatgct atttcatcaa ctgtatccat accttctatc actctaccaa aacctgcata
      361 ttgaccatct aagtgtggtg agtttttatg cattatgaaa aattgagaac cagctgaatt
      421 aggtgccata gttctagcca ttgatatgac tcctctttca tgttttaaat tgttagtaaa
      481 tccattacca ctaaattccc cttttattga gtgacctgga ccgcccattc ctgtaccatt
      541 tgggcaccct ccttgtatca taaatcctgg tattactcta tgaaatatta ttccattgta
      601 atatccttca tttactaatg atacaaagtt tttaactgta tttggagcta tatttggata
      661 taactcaatt ttaatttctt ttccattttc catttctata gttactatag gatttttatt
      721 ttccataatt tattaccttc cttttcatta gttaaattac ataattacat ttattatatt
      781 atactctaaa ttaaagtcta tcaagtatat tttttcctat ttcgtatcct tcctgataaa
      841 tagttttaca aaactcatca tcaaagttaa gtgtatcttt aggagcaaat tgagtgttag
      901 gtctaactac tattatttta tcttcatcgt atattttttt aatattctct ggcaactcat
      961 aattatattt tgtggatatt aaaataattt tatccacatt atccccaatt aatggttcaa
     1021 ttaatgcact cctaattaaa cctccatcta atttgaaacc atcataaatt ccttcttgca
     1081 catctttcac aaattgttct ttaaatccaa gagttgcatt tggatttgat ggcaataacc
     1141 cactgtatga aatactgata attgcttcat tacgaggcat ttttgataca tcaacaatct
     1201 tttctgatac taccttatta tcaacttcaa cataattaac ataaaagttc atttcttcta
     1261 tattactatc atctagttcc cttaggttgt ctatagcagg agaattatcc acagtattat
     1321 ttactatttt cacattccca ttctggatat cttttatatt tgtccacatt ttctccaagt
     1381 tatcaacatt ccctgtgtac aaataatatc catttattgc tcctattgat gtccctgaaa
     1441 tagaataaaa tttatttatt cctccatcat acaaggcttt aactactcct gcttgataag
     1501 ccccttttgc tcctccacct tctaagcata atcctaattt catagtctca tctccaaatt
     1561 gtttttctta tatttatatt tcaaaaaact tactaaatgt tttatatata ctatagtggt
     1621 cctcgacatt tcctaattct cttatagagt gcattgctaa aattggactt cccacatcca
     1681 cagatggtat atctatatga gtagaagata ttggacctat agtacttcca cctctttcat
     1741 ctgacctatt aacaaattct tgatattcaa cattagcttc tctacatata tttttataaa
     1801 tagctataga atatccatca ctagtatatg cctgactagc atttatcttt ataactggac
     1861 cttttcccat aattggttta ttagttgggt catgcttttc tggaatgttt ggatggatag
     1921 catgagctaa atctgatgat atcataaaag atgaataaat agattcaaag aatccttctc
     1981 tatccttacc tattgatatg caaatcctct ccaatatatt taacaacatg tttgaatctg
     2041 caccttgttt agtagagcta ccaacttctt cattatcaaa tacagccatt acatttacac
     2101 catgttgacc tttagtatta acaagagcat ttaagctagc atgtaccatt gcaagattat
     2161 cttgtctccc aatagatata aattcatcat tagcacctat taaacttcct ttttcaaatt
     2221 catataaaaa taaatcaaaa tctataatat cttccatatt tacatctaag ttagatgcta
     2281 tttgctttat aagaaaatta tctttttcta atgtatcatt taacagccca actaaaggta
     2341 acatatcttt ttgcttatta tatgaatgac catcatttat gcttctattt aaatgtatcg
     2401 ctagatttgg tattatacaa attggctttt taaagtctat aagcctttca tttggtttta
     2461 atatactatc accttttaaa actactctac cagctatccc aagaggtcta tccaaccatg
     2521 tacttaatat tgctcctcca tagcattctg tatttaactt caaataagat ttttcagctt
     2581 ctatttctgc atttggttta atactaaatg taggagaatc tgagtgagag cctattattc
     2641 taaatccatc tctttctata tcttctgaat ttactacaaa agctactata gctgataaat
     2701 tcttagtaac ataatacttt ccaccaaccc ttagattcca tctctgattc aaaactaatt
     2761 cttcaaatct atttttatct aagatttcct tagtactctc gactgtatga aaagacgacg
     2821 gactatcata tatgaagtct attaagtttt tagcaaagtt tatactatcc attcctcatt
     2881 tacctccatt ataaaatatt tagtgttgta tattctttat ttattttttt aattccctgt
     2941 tggtcaaaag ctatagtaac atctgtccca attatagaaa ctactgtccc aaccccaaat
     3001 ttaggatgat gtactttaga accaagtttt atatcatctg gattagtttc tttattagaa
     3061 tcttttattg tagcattaac tttatctgca actttagatt tacttatagt actcatatac
     3121 tttttagtat atttatctaa catattataa cttgctttag aatagcttag ttcttttttt
     3181 actttgtaca atctttctat acattcttct ggcagttctt ccataaatct ggaagctatt
     3241 gcaacatttg ttttaccata taatgttctc ttctccgtca atgacatata tagctcttct
     3301 ttagctctag ttataccaac ataacaaagt cttctctctt cttctatttg tgaatcactc
     3361 atagatttta tagctcttga tataggaaat aatccttctt ccatacctgt taaaaacaca
     3421 acagggaact ctaaaccttt ggatgtatga attgtcataa gcgaaaccct atcattgtct
     3481 tcctcatcat ttgattcaga tgtaagtgct atacttgtta ggaatgtctc taagtcttta
     3541 ttttcataag tatcatcatt actactttca aactccaaag ctatagatat aaattctctc
     3601 aaattatcaa ttctgtcttg agcttcttca cctttacctg ttaaatcttt ttcattttta
     3661 tttcttatct ctacaagctc gtccatatat cctgtagtgt ccaaaacttt ttctataagt
     3721 ttactaacag gataaacttc ttttatagtt ctaagagtcc ctataatatc aacaaatcca
     3781 cttatacttg ctcttgcctt ggtagatata tctgaatttg tttctatatc aattagtact
     3841 gagtatatgc tctcttgttt taaattagct ctatcttcaa ttttttctat agttctaagc
     3901 cctatacctc ttctaggaac atttataatc ctttttatag atatatcatc ttgtggattt
     3961 tgaataactc ttaaatacgc caacaaatcc tttatttctt ttctctcata gaattttgta
     4021 ccaccatata tattgtatgg aatttgactt ctatttaaag cgtcctctac aggtcttgcc
     4081 tgtgcatttg ctctataaag tactgcaaaa tccttataag gtctattttc ttttctagct
     4141 atttgtgcaa ttgaatcagc aatgaaatca gcctcttcta tttcgctacc agttaattgt
     4201 atctttataa gttctccttc ttttttttca ctccaaagct tttttctttt tctttctata
     4261 ttattagata taactttatt agctgcatct aatatcactt gtgtagacct ataattttgt
     4321 tctaatttta caacatgtac attgtcataa tctttctcaa attcaagtat gtttcttata
     4381 tctgcgcctc tccatccata aatactttgg tcatcatctc caacaacaca aatattttga
     4441 tgttctcttg ctaataattt tatcaattca tattgagctt tacttgtatc ttggtactca
     4501 tctaccatta tgtatctaaa tctacttcta taatatgcta acacttcatc attagcttta
     4561 aaaagttcta cagttttaag tattaaatca tcaaagtcaa gtgcactatt tctttttaaa
     4621 cggtcttgat ataacgcata aatatctgca atcttaacca ttctattatc tgccatattg
     4681 atatctttaa actgctttgg agtataaagt ttgtcttttg ctcctgaaat tgcacttata
     4741 actgcttttg gttcaaacac tttatcactt aaatttaatt cttttagaca gtctttaacc
     4801 aatgtaactt ggtctgctga atcataaatt acaaaacttc tattgtaacc aatcttattt
     4861 atatcttttc ttagtatacg aacacagcaa gaatggaatg tacttatcca catatcctta
     4921 gtttcaggac ctatgttttg ttcaactctt tctctcattt catttgcagc tttgtttgta
     4981 aatgttatag ctaatatatt tggtgcttgt acacctttat cttctataag atatgctatt
     5041 cttgttgtta ataccttagt tttacctgaa ccagcaccag ccagtataag tactggacct
     5101 tcagtctttt ctactgcttc tctttgagca ggatttaatg tatctaaatt catatttctc
     5161 ctcctgttaa cagccataaa tatattttaa tctaaaatat gaattacttc aaattataat
     5221 tatgtattat atcaatagat tatttccaat atattacaat taaataacat ttttccatat
     5281 aatttatttc attgtttaat aaaaaaaata accttatgat ttggggaatc ataaggcacc
     5341 tttaaggggt ctaggttaag ggttattata tataaatcta tttttttaaa ataggtttag
     5401 ggctaattat ttatttgtat taagttctct ttctttccaa tacttataca aatcttcttc
     5461 tttcttaaat aaaggtaaat tcatattttt atgtactttt actaaccatg gggattctag
     5521 accagcttgt ataatattat tttcatttat aaatacattt tctgcctttc cttcatcaat
     5581 caaaatcccc ttatccaata catatatgta atcacatatt tcatacatta aattcatatc
     5641 atgactggat attactattt ttatattatt tttatttaat ccctttatta tatctacgat
     5701 agacctagtg cttactgggt ctagaccagc tgtaggttca tcaagtaata caatttcatt
     5761 ttccattgct ataactgatg ctattgccac cctttttttc tggccataac taagaaaatg
     5821 tactggtctg tctataaaat ctattccatt aacagctact agagctttgt ttattctctc
     5881 tttaattgtt ttttcatcta taccaatgtt tctcattgca aatgctatat catcatatac
     5941 ttttgaataa aaaatttgtt tttctgggtc ttgaaacaca atacctacat tttttcttag
     6001 attgtataaa ctttttttat catactttaa cttctcttct ttaaaaaaaa tttctccaga
     6061 ggtaggcttt aatatcccca ttaagttcat aaataatgtt gattttcctg aaccatttga
     6121 acctattata cctataacat ttccctttga aaaatccata ttaatgttta ataatgcatt
     6181 ggcatttttt tcatattgat acgttaaatt atttatttta aacatcatta tcccctacta
     6241 tgtgaaattt accatcatac aattttatgt ctaatgatat acacatatca tcataccttg
     6301 tcataagtct tttgtacagc atacttccaa gaattcctaa ggatttatat gaagttttta
     6361 aatttatata accaaatctt agctcttgtg acttgtatat ttctgaaaat tcttctaaaa
     6421 atatgaatat aaacctatat attaacattg ataactcaac gaaagtgtca ggtaaatgaa
     6481 gttttttaaa aaagaatatt aattgattaa aaggtgttgt aagtatacaa aaatacacac
     6541 aagtcaaaca agacatagct ctaaataaca cgtgaataga catgtcaata gacgcctttg
     6601 atattcctac attaaaacta aaaatttcaa aactatgtaa taaatctgct ttattaaaag
     6661 atatatttac aagagttatt cctatactaa gaaataaaaa gtacattggt atcctaagta
     6721 attttaaata gttttttaaa tctattccag ccacacaaac aaccagaata ctcattaaaa
     6781 tcataattcc acttaaaata aatatatttt gtattaccat agaagcaatc agaaagatta
     6841 ctcctatggc tacttttttg tttggattta ctttacttaa tctatttgta tatgcatatt
     6901 tatcaattat aagcatgatt aacttctctt tcctttttga agacctaata tgtatcctat
     6961 tacaccagca cctaaagctg cttgtgcaga gaataataaa ctttctattt ctccacttgg
     7021 tggctcatat ggactgctaa accatggttt gtaatttgga tttatcttag taatttcact
     7081 ttcagcttga ccatctgctc ctccatattc agcacctgag ttgacaagta acgggaatat
     7141 aataagagcc actactaata aaagtaataa tatgttagtt tttgtttttg ttttagcact
     7201 cattagcttt aactccttta tcattatttt ctagtatgct tttttctcca ttttctgtaa
     7261 ttaaattata tacaattaca gtaagtatac cctctgctat tgctattggt atttgagtca
     7321 taaagaaaat tcctaaaaac ttaattgctg aagccatcac tccacctgat ggatctggaa
     7381 aagctagtgc taactgtatt gaagtaattg tatatgtagc caaatctcct agtgctgctg
     7441 caagaaatac tggcattgca ttatttccat cttttttctt taatgcttta aatattaaaa
     7501 atgatacaat tggtcctata atagccattg aaaaagtatt agctcctaaa gtagttatgc
     7561 ctccatgtgc taatagtaat gcttggaata ttaaaactat agttccaaga acaaacatta
     7621 cgcttggtcc aaacattata gctccaagac ctactccagt aggatgtgag caacttcctg
     7681 ttactgaagg tatttttagt gctgacaata caaacacaaa tgctccacat agcgctaata
     7741 atactttctt tttagggtct tgctttacta tttttccaat tgattttagt cctactaaga
     7801 aaaatggtat aaatataact ccccatgcta tagaccattt tactggtaaa taaccttcca
     7861 ttatgtgcat tgcatttgat gtaactggag ttaaaatgat taacataagt gcagctataa
     7921 cccctaattt gatattttgt ttcattttta gtatcccctc tctccctttc taataatcaa
     7981 aatataagtg atacatgtct gatttatttt aaataaaata aaaaaaccta actcgatggt
     8041 taggcttcta attttccaca atccaaatac aaacacataa aacaaacata tctgtataat
     8101 tattataaga aactttctcc atccccgaag aaattacttt aatattttag gcaggtctcc
     8161 tgacttagct tcttcctaat cctcttcctt cccatgagat ataaaaaata tcatcatagt
     8221 ggctaacaaa agtttcgtct gcatcacagt agcgggggct gtaaaggaat ttaacctttt
     8281 tccctattaa tcttgcttga agaacctata atattatata tttaattttt aaattattct
     8341 taaattgtat tctatataaa tcattgtata ccttttctgt gaaaatttct acatttttta
     8401 taaattttat
//
LOCUS       DBGJFK010000114         7636 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.121, whole genome shotgun sequence.
ACCESSION   DBGJFK010000114 DBGJFK010000000
VERSION     DBGJFK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.121"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            118..969
                     /locus_tag="ACOIAP_003427"
     CDS             118..969
                     /locus_tag="ACOIAP_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGZ2640299.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDISIAISYSGESKEVIKSIENAKLKGCKVICMTKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNIDNA"
     gene            1580..2614
                     /locus_tag="ACOIAP_003428"
     CDS             1580..2614
                     /locus_tag="ACOIAP_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HGZ2640300.1"
                     /translation="MKKIRKLATKLLITTMVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDVIYKSLSHPLPFDKTAYPTVGAVAQTQKKPAPPGKHTMLPHQEGA
                     KVVGKFGDIKDKHVMYEGVRCVVINSSVNTVTFMGSESNLDPSELTIAVIGFMNTPYG
                     MFALAPESKPVEYPFEYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIEITDEKANTG
                     LGQIMYIRYE"
     gene            complement(2730..3704)
                     /locus_tag="ACOIAP_003429"
     CDS             complement(2730..3704)
                     /locus_tag="ACOIAP_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGZ2640301.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKVYGFLLCTIFSYLCFNILGYNLISFSVFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYFLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGHTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKNAQMLRDNNFYK"
     gene            4176..5057
                     /gene="pepI"
                     /locus_tag="ACOIAP_003430"
     CDS             4176..5057
                     /gene="pepI"
                     /locus_tag="ACOIAP_003430"
                     /EC_number="3.4.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase"
                     /protein_id="HGZ2640302.1"
                     /translation="MKITEGYMPFEGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIKELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSARLWEKEQKRRISYMSESDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGARDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIEVLTEWLDAND"
     gene            complement(6281..7066)
                     /locus_tag="ACOIAP_003431"
     CDS             complement(6281..7066)
                     /locus_tag="ACOIAP_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640303.1"
                     /translation="MKKQKIITSLLITGVLATNTYPVFASQAIQTQNLTSIEQRISSN
                     VLLKCDQSSINYTNFFKNGGGEQWVKLTLEGAKFNTNDPYEIKNAIKQNYDVQTTIAV
                     GTDGKSIEFGVYEPNAGIEYLPNWEININSSVLTSDTDATIKIPVNYDIHTSATPKII
                     TSKKSITLDELKNGFELDLEGIQGAQFNTDCVGNNVRLSLMHTANIPVMAMTYCDLDT
                     THIGFIIKALNDIPSTATEFTFRIEGNATTSQVPLLVKLPIVK"
     regulatory      complement(7421..7508)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT         2858 a          920 c         1230 g         2628 t
ORIGIN      
        1 ccctgtgact ttagtcatgg gaggttcaga tggtgagacc agtgttgact ccagatttag
       61 gagcatgttt acttgctaag aagaaatatt atagtaaata ggtagaggtg gtagagtatg
      121 agttgcattt taaaattaaa acagatatat gaagatttaa cagaagtaga taaaaaaata
      181 gctgattaca tacttaataa tacagaggct ataagtaagc tttctgtatc agaattggcg
      241 tcaaactcaa aaacgagtac agcaagtata gttaggtttt ctagaaaaat gggatattcg
      301 ggttttggag atttaaaaat tgagatagct aaagatttga tgggcaaaga aaatgaatac
      361 acatatgtag atgaaaacta tgattgtaat atagatagtg ttataaacaa aattacaaac
      421 aaaaacatag agactatcaa ccaaacaagg ttgttgaatg aaaaagatat aataaaagaa
      481 gcagttgaac agataataaa ggctaaaaat gtatacatat ttggagtagg tggttcggct
      541 ttagttgcac tagatttaca gatgaaactt ttaaggataa ataaacaggc atttacctct
      601 ttagatagtc atacacaact tatggtatct tcaaatgtag ataaagaaga tatatctata
      661 gcaatatctt actctggaga atcaaaagaa gtaataaagt ctatagaaaa tgcaaaatta
      721 aaaggatgta aggtcatttg tatgactaaa tatagtgaca atcatcttag taagattagt
      781 gatttaaagc tagtagtacc aaatatagaa aaaaggctta gagaaggagc tatttcttca
      841 agaatagcaa tgcttacatt gatagatata atatatattt ctataattca agaaaactta
      901 aatgaggcag aacagaaact acaagaaaca aaaaggatac ttgattattt aaatattgat
      961 aatgcttaaa actaggttat atatcaacta aacaaataag ttagactata agcgtaagtc
     1021 aataagaaat atataaatat ctaaaatatt gacttactca ataataatat atagcatttt
     1081 ataatacaaa tgagttgtct taaaatttat tttttttaat caaattttaa gttcaactcc
     1141 ttttttatat tattatagat atatcctata ttttcccaaa aaacgtattg aacatacaaa
     1201 ttataggagg tataatgtta tggagagaga atatatgaaa tgtatacaaa attgatttta
     1261 actgtattat tgataattct ctttactctt accattacta atgattgaag acagtagtat
     1321 ttatcatagg tcaaagattc cgaatatatt aatcatcatc attttctcaa attaacagca
     1381 aacatactga tttgcgagtt gtattgtata caaattatct agaaaatatc tattagattt
     1441 tccatgaaat ttaaatattt cgcgaacgta tgaacgtaga aacatacatg ttgacaatcc
     1501 acatttttaa atcccaaatg agctttatta atggtagaga ataggaagta acaatatttt
     1561 ataaaggaga atactaagta tgaagaaaat taggaagtta gctaccaagt tattgattac
     1621 aacaatggtt ttaatctcag gtatgagtat gacagtttat ggtatgacag ctaaagaggt
     1681 aacagcaaag acgccaaaaa gctacgtcac tggaaccaat agcgtatatg gtccgaagtt
     1741 gtcacaagcc caactgaact cagtagcaca agcaacagca gattttatga acaagaaaat
     1801 cacaaagaac atgactacag atgctaagat tttagttgcc tacaatcaca ttaaaaataa
     1861 cacaacatat gttgactgga atgcagtaga gggagcaaat actgcctata cattggttac
     1921 taaaaaaggt gcatgttcag gaatggctag gagcatgaaa gctttgtgtg atgctatggg
     1981 aattgaatct tattatgtac acagcacatc aaatgaccac cagtggaatc ttatccgttt
     2041 tggtgatggg cgtttgtatc atgtagatat tgatgctaat aaatcagcag gaaaggatgt
     2101 catatacaag agtcttagcc acccattacc atttgataag acagcatatc caacagttgg
     2161 agcagtagca caaacgcaaa aaaaaccagc accacctggg aagcacacta tgttaccaca
     2221 ccaagaaggg gcaaaggttg ttggaaaatt tggagatata aaggataaac atgtaatgta
     2281 tgaaggtgtt cgatgtgttg taattaattc atcagtaaat acagttacat ttatgggtag
     2341 tgaatcaaat ttagacccat cagagcttac gattgctgta ataggattta tgaacacacc
     2401 atatggaatg tttgcattag cgccagaaag taaacccgtt gaatatcctt ttgaatatga
     2461 taagccattt tctttagatt ttagtggtaa aaatcgttct ggtgcagaat tagcgaagta
     2521 ctgtaaaaaa aatgatgtga ctattaaaat agaaatcact gatgaaaaag ctaatactgg
     2581 acttggtcaa ataatgtata ttcgatatga ataatgattt aatcatgaca gtagaataag
     2641 ttatgaacat tgcgccctct tactaggggc gcatttaata ttatatctga tattttgtag
     2701 tcaggtcaac tgctggattt ctcccctttt tatttataaa aattattatc tctaagcatc
     2761 tgagcatttt tacgattaac taaaaactgt tttaactcag tcaagcatag gaataaaata
     2821 gccctatttt caaattctgt tctgtcaaca ggtagaggtt ggtttttcat actaagcatt
     2881 aatctcttca attcttcaag aagaagattg cctgtttcag cttcaaattc agtatgacct
     2941 attttatgta tgaaagcaga gaggatatga gcttgtggtg gtgtagaatt tagttgagat
     3001 acgtaactat acaaattttc taagatatcc cgttgacttt ttataatgtc catatgttct
     3061 aagaagaatc tagtatcact caataaagta ttattaatat tatcgtaagt ttcagaaata
     3121 ctgctgtcaa taagtgaatt taatgtatat aaatctctac tatatccatt ttctttttta
     3181 gggtttacaa taatatctgc aatgtctata agtacaatac tcacttcttc ctgtaacttt
     3241 ttttgaactt catggatttt atgtatattt gttggaatat acatatttat taagacacct
     3301 attccagttc ctactgcaaa tattccagct tcgtttaaaa tccacttaat agatgtttct
     3361 ccttgaagaa aataatggga ggcaatgact acacacatgg caataacatc ttgaatattt
     3421 aataaaaaac aaagtggtat aattataaat ataaatactg aaaatgaaat caaattatat
     3481 cctaaaatat taaaacataa ataggaaaaa atagtacata aaagaaaacc ataaaccttt
     3541 ccaatagagc ctttaagagt ttctctttta gtatctttta ctgtaagtag tactataact
     3601 ccagcaacca ttgaatattc taattttaat agccaagcaa taaatatagc aagagaacat
     3661 ccaagagaca attttattac tttaagtgaa ttaatattat tcaaatgcaa acctccttta
     3721 aacaaatata gtaaagataa ttttagcata aaactaattt tgtttaaaat atagttaacc
     3781 atattttatt taaaaattat tatacaaatc aataaaaaga taagtaagtg tggatacaaa
     3841 gatacctttt taatgtaaaa tattgtagaa tacaaaatat tataatgaac acaaaataat
     3901 tataatctat taaataaaaa atactttaaa ttacaattag agtagttaat aaaataactg
     3961 aaaatatatc tattattatt aacaaaaaat aaaattatat agttaatgta attttataat
     4021 tgatttggta tggagatttt tttcttttgt gttatactat ttatgaaagc aaatagaaac
     4081 attaaaatac attattaaat atgtatgaga agttttaagt agccttatta atgaacttga
     4141 ttattgttca taatagcaaa ttggaggaga taaacatgaa aattactgaa ggatatatgc
     4201 cttttgaagg ttttaaaact tattatcgta tagtaggaga aaatacggaa gggaagaagc
     4261 cattagtact acttcacgga ggtccaggtt ctacacacaa ctattttgaa gtgttagaca
     4321 agatagctga aagtggtaga caagttataa tgtatgacca aattggttgt ggtaattcat
     4381 ttgtagaagg gcatcctgag ttatttaatg cagatacttg gataaaagag cttattgaac
     4441 tgagaaaaca tctagggctt gatgaaattc atctgttagg tcaatcttgg ggagggatgc
     4501 aggctatttg gtatgctatt gaatataaac caaaaggtat taagtcttac atcctttcat
     4561 ctactctttc ttctgcaaga ctttgggaga aagaacaaaa aagaagaata tcatatatga
     4621 gtgagtctga ccaaaaagca ttacttgatg cagtaaatac tggagattac tctagtaaag
     4681 aatacaatga tgcattagaa agatttatgg aaatgtattg tgcaggtgaa gtgacagaag
     4741 attctccaga gtgcctaaga agacctaaaa aatcaggttc tgaagcatat attgtaggat
     4801 ggggacaaaa tgaattttct cctacaggaa ctctttctgg atatgagttt acagatagat
     4861 tacatgaaat aaaagagcct tgtctagtaa ctagtggagc aagagattta tgttcaccat
     4921 atattgcaaa gactatgtat gatagaatac ctaatagtaa gtgggagtta ttcgagtatt
     4981 caagacatat gccattcgtt gaagaaaatg agaaatatat agaagtctta actgagtggt
     5041 tagatgctaa cgattaaaaa taatataaat ttatacaaaa gagaggctag acatgttgtc
     5101 tagtcttttt ggtatgataa aagtgtaata gtttatatta taaacgatgg tatatttgta
     5161 cttattttaa aatctattgt gtctaagaaa aaattaatag ttgtagtaat gagtataatt
     5221 gtaattaaat agtgagcttt ttatatgttc attcaagaat aaatgattca tcatgaggaa
     5281 atcatgataa taaaaataaa tattgttcag gaagttatca ctatccattg tggtagttat
     5341 ccagttcatt tacatgataa tggagtatcc ttataatgga ggatagaagt atctgtagag
     5401 caacaacctt ttttatatac aatatatata taaagtaata tatattgtat ataaaattta
     5461 ttatgattta ctaagatttc taattgacat tatatgtatt tagaggtact attatattaa
     5521 tttaaattta ataactatta gaataaatat ttattccgaa aagatgcttt aaagtaaatt
     5581 acatttttat ttataataag agatgcaagt gtaatgtttt agatataata attacaagta
     5641 tatataaatt atactaatgg ttttatagta gctaagtgtt tatatggtaa taaaaattgt
     5701 aattgtaatt tatgatggtg ataatacata aatgaggttg gcaatgataa gcttatgtag
     5761 tttattaaat aaaaattatt aataatcaat tatcaatgat tattttaact tatgcttttg
     5821 cattatatgt gtaaatataa caattgaaga tatttggtat ttgaaatttc tagttttatg
     5881 agaaacataa tatcgctcag ataaatttgt tatgacatta caagaatttt taaaggtata
     5941 ttgcttaaac ttaaaggcaa agatatattg tcagataaag cagtatctat taaagatgaa
     6001 atttttatta aagagcaagt agaaactgtc atatatcttc aaatttagta agtattattt
     6061 tgtgaatatc tttgccttta ttaatttgta ttgattgttt ttcaattaaa tcttctatta
     6121 tagttgatta tatgaaaaat tctgtattat ttagtaatca taatatagtt tagtttctct
     6181 gcttattgta taagttttta aagcagatgt aatgtagctt agttatagtc atagggataa
     6241 cagtattagc ttttaaagtt tatattatat gtttaaagtt ttattttaca ataggaagct
     6301 tcactagtaa tggtacttga gaagttgtag catttccttc tattctgaat gtaaattctg
     6361 ttgctgttga aggaatatca tttaaagctt ttattatgaa accaatgtgt gttgtatcaa
     6421 ggtcacagta tgtcatggcc attacaggaa tattagcagt atgcattaag ctaaggcgga
     6481 cgttgttacc tacacaatct gtattaaatt gagcaccttg tataccttca agatctaatt
     6541 cgaagccatt ttttaattca tctaatgtta tacttttttt acttgtaata attttaggtg
     6601 tagctgatgt atgaatatca tagtttacag gtattttaat agttgcatca gtatctgatg
     6661 ttagaacaga agaattaatg ttaatttccc agtttggtaa gtattcaata ccagcattag
     6721 gttcatatac tccaaattca atggattttc catctgtacc tacagctatt gttgtttgta
     6781 catcatagtt ttgttttatt gcatttttaa tttcatatgg atcatttgtg ttgaactttg
     6841 caccttcaag ggtaagcttt acccattgtt ctccaccacc atttttaaaa aagttcgtgt
     6901 agttaattga tgactggtcg catttaagaa gaacatttga agatattcgt tgttctattg
     6961 aagttaaatt ttgtgtttgg attgcttgag atgcaaacac tgggtaagta tttgtagcta
     7021 atactcctgt aattagtagt gatgtgataa ttttttgctt tttcattttt gtttcctcct
     7081 ataatatgtt atatttttaa cagtgaaatg aaataaaata caagggcaat ataaaatata
     7141 tgtcgttttg aagtgtatta agattgtgtg aaatattatt agttatactg aaatatacta
     7201 gtctatagat atacatagtt taaaataagt aaagtagtat tactgtctta cttaacactc
     7261 gtttttaatc cataaaataa tgttttcaga gttaaataat tatctttcaa atctaatctc
     7321 aattctttag catagaggtt atagatacaa taataagaat atggctagaa caaaaaaata
     7381 cctcataagg aggtattatc taacaaaaag tacactaact tttagtaact ggcaggcata
     7441 atctttttaa gaccttaacc cctatagctt tgcgtcccta gatttctcta ggtttgccta
     7501 ttaagttttg cgtttgcatt tttaatatca tatcaatctg ttttatagaa tgataacaca
     7561 aataaaactt ataatcaaca attacatgaa atttttggaa aaaaattata tattacaaaa
     7621 ataatatttt cttcat
//
LOCUS       DBGJFK010000115         7604 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.122, whole genome shotgun sequence.
ACCESSION   DBGJFK010000115 DBGJFK010000000
VERSION     DBGJFK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.122"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            197..1018
                     /locus_tag="ACOIAP_003432"
     CDS             197..1018
                     /locus_tag="ACOIAP_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGZ2640304.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKNLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGIPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            1039..2235
                     /locus_tag="ACOIAP_003433"
     CDS             1039..2235
                     /locus_tag="ACOIAP_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HGZ2640305.1"
                     /translation="MFIEFFYLLRSRGVNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDTVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWVLKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFRRKYSKTVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            2401..5799
                     /gene="cspBA"
                     /locus_tag="ACOIAP_003434"
     CDS             2401..5799
                     /gene="cspBA"
                     /locus_tag="ACOIAP_003434"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional germination protease/germinant
                     receptor pseudoprotease CspBA"
                     /protein_id="HGZ2640306.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNTLLTYPEIEFIEKPFVLQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSNGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELKMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLRNNITEEVEF
                     IVGEGERILNVNIWPDFVDDFSVHLVNPSNNQTQTISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWRIIFEPINIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKVARRLSNQSY
                     PNNSSGFGFLNLSDVDLYTLSSINQDLETEDIGYRSINKSFMDEANNYIPIDGYNVQI
                     HNGLEKEKYISKNISRQSGILSGIDVVHTPEFEEELAGLGQSQNFLKISDSLGVLSID
                     NTDYNSIQQVLQLPSIIRTIPTTKMTLLGEINRGTFGGVVATEEIGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHRDFIYPDGTSKIVYLWDQTKEGNPPDGFYIGTEYTREDIN
                     RAIAANDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGVAEDSELIVIKLGKIEGFYNS
                     AMLFAASQYAYNKAFELGRPLVINVSLGTSSLAGLTNRVNSEKAFFTRGLCVTAGAGN
                     EGNTQTHTSGIISHVGGSVEVELELNEEEEELSLELWLSRPDKADVIIVSPTGEESKT
                     VGVSNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRKLLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINSSLWQSSSRG
                     PTIENRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5809..7482
                     /gene="cspC"
                     /locus_tag="ACOIAP_003435"
     CDS             5809..7482
                     /gene="cspC"
                     /locus_tag="ACOIAP_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid germinant receptor pseudoprotease
                     CspC"
                     /protein_id="HGZ2640307.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPIDFDET
                     ILNNIIQVAWWEESAPMSSLIEITNNVDNGETITTAAGTEYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILAGNGRVNSKYRGITTESDLIVVKLKSYIGTYYAGRINYSV
                     SDFLAAITYVTNIARTENRPLIINLTIGVKSGAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYAPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWTLRLTSELI
                     IGGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVAPGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQNNI
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
BASE COUNT         2918 a          866 c         1437 g         2383 t
ORIGIN      
        1 ttattattct ttaaaatata tatttcattt aattatgaca aataaagata aaaattaaat
       61 attttagagg taattttatt tagatataga attttagaat aatactatac aaatgtatta
      121 cattattgtt ttatatcaaa aatagtaata aagtatatat acatttagaa aatactgttt
      181 aaaaggagta gaatttatga taaaaaaaga gatatctaat tttagaggaa gtagtgatta
      241 tgttgtatca ccagaattga tggcatcagt taatgttgct attgcacttg aaaaaccact
      301 tttgattaag ggagaacccg gaacaggtaa aactatgcta gcacaagcaa tttcaaatga
      361 attaaaaaaa aatttagtaa tttggaatat aaaatcaact acaaaagcac aagaggggct
      421 ttatgtatat gatactgttc aaagacttta tgatagccaa tttggaggag aaggtgtaga
      481 tgatattagc aagtacataa aatatggtaa attaggagag gcttttagtt caaatcaaca
      541 agtaattctt ttaatagatg aaatagataa ggcggattta gaatttccaa atgacttgct
      601 ttgggaattg gataaaatgg aattttacat aaatgagaca aaagaaactg taagagcgaa
      661 acaaagacca atagttatta taacttcaaa tgcggaaaaa gaacttccag atgctttttt
      721 aagaagatgt atatttcatt atatagaatt tcctgataga gatatgatgg aggaaatagt
      781 caaagtgcat tttgataaag tagaagaaca cctattggaa caagtaatga ctacttttta
      841 ttggattaga agtttaaagg atatacaaaa aaagccgagt acatcagaat taattgactg
      901 gatacaagca ttaacattga gtggaatacc tattgaaaaa atagaaaaag aagttccttt
      961 tgcaggaata ctacttaaaa ataatgagga tattgaatct atgcaaagac acttatagtt
     1021 aataggagct ggataattat gtttattgaa tttttttatt tattgaggtc aagaggagta
     1081 aatgtatctt taaatgaatg gatgacttta attgaagcat tggataaagg actgtgctat
     1141 tcaaactttt caaattttta ctatctttgt aggatgattc taataaaaag tgaaagtgat
     1201 tttgataagt ttgacacagt atttttagag tactttaaag gtatagaaca tcaagaggaa
     1261 attccagaag agattatgaa ttggcttaaa aaaccagata tagatttaga agagtttgaa
     1321 aggttagaac aaaatccaaa tataaatctt gacaaattaa gagccaaatt agaggaacga
     1381 ataaaagagc aagattctcc tcataatggt ggtaattatt ggataggaac agggggaact
     1441 tctgagttag gacattcagg aaaagggcaa actggtatac gtataggtgg aaattctact
     1501 tatggtagag ctgttcttga agttgcagga gaaagaaaat acagagattt tagagatgat
     1561 gaagttttaa atatgcgtca atttcaagtt gcactaaaga gactgcgtca attttctact
     1621 agaatagatg ctccaaagac agagcttgat ttggataaga ctattgaaga gacttgtaat
     1681 aatgcaggtt atttaaaact gttttttgag aaaccaagaa aaaatacagt aaaactttta
     1741 ttacttatgg attcaggtgg ttcaatgaga gggtatagca ctttatgcaa tacattattt
     1801 cagtctgtaa gtaaatcaaa tcattttaaa gatgtaaaga tatactattt tcataactgt
     1861 atttatgata gattatttac aacacctgaa tgttggttaa gtaaatctat taatactgaa
     1921 tgggtattaa aaaatataga taaaaactat aaagttataa ttgttggaga tgcttctatg
     1981 tcaccttctg agttacttca tattggtggt aactatcgtg gtccatataa ttacacacct
     2041 ggtatagagt ggcttaaaag gtttaggaga aagtacagta aaactgtatg gatgaatcca
     2101 gaactgagag atggatggga ttcaattaat tattggtatc aaactcaaag aatgatacaa
     2161 agtgaattta atatgtttcc actgactgta aaaggtcttg agaaagcact gaaaaattta
     2221 atggtttcaa gataaagtaa atataaatga tggtatgatt tattcaaaat tgtaccatca
     2281 ttatttattt ttttagtatc tctattataa attatataat tgaaacttaa aaattatata
     2341 gtctgataca ttttagactt acatagaaca tatacattaa taataatttt agaagtcgag
     2401 gtgattataa taaattatga attaattgta aaatacaatg gagatatatt gagattagaa
     2461 gaagaactag gtgtatcagt agagatactt aattcatcat atgcaataat aacatcaagt
     2521 aatgaagaag atgtaaatac acttttaact tatccagaaa ttgaatttat agaaaagcct
     2581 tttgtattac aaactcagga tgtacaaagt ttttcaagta caggaataac agggtttaaa
     2641 aatagaactg gtttaactgg gaaaggaact ataattggta taattgattc tggaatagat
     2701 tatactttac ctgtgtttag agatagtaat ggtaggtcta agatattata ttattgggac
     2761 cagtctattc agggaaatcc accagaaggt tttagagaag gaacattata cactaatgaa
     2821 gatataaata atgcaataga tggaagtatg tatataccta tttcaacaac tagtttacat
     2881 gggacacatg ttgcaggtat ttgtgcaact attgcaagtg atgccagaat aatagtggtg
     2941 agagttggaa atatacaaac cgatattttt tcaagaagta cagagtttat gagggcaatt
     3001 aaatttattt tagatagagc attggagtta aaaatgcctg ttacattaaa tataagttat
     3061 ggaagcaatg aaggttcaca tagaggaacg tctttatttg aacaatatat agatgatatg
     3121 tgtttatttt ggaaaaataa tatagttgta gcggctggaa ataatgcaga taaaggtggt
     3181 cataaaagga ttagacttag aaataatatt acagaagaag ttgagtttat agttggagaa
     3241 ggagagcgta tactaaatgt aaatatatgg ccagattttg ttgatgattt tagtgtgcat
     3301 ttagtaaacc catcaaataa tcaaacacaa acaatatctc taacttcagg tgaaataagg
     3361 aataccttgg gtgaaactag aataactggt tatttttatc ctatagcacc atattctctt
     3421 acaagaagag ttactttgca attaagttca aatacacaaa taactccagg attatggaga
     3481 atcatatttg aaccaataaa tatagtaaca ggtaatgtaa atatatattt accaacttct
     3541 gaaggactaa atagaaatac tagatttttg attcctactc aagagcttac tgtaacagtt
     3601 cctggaacag caagtagagt tataacagta ggcagtttca attcaagaac agacatagta
     3661 tctatatttt ctggagaagg agatacacaa ttaggcgtct ttaaacctga cctattagct
     3721 ccaggtgaag atatagtatc ttttttacca ggaggtacaa gtggggcatt aactggaact
     3781 agtatggcaa ctcctcatgt tacaggggtt tgctcattgt ttatggaatg gggaattgta
     3841 aatggaaatg atttattttt gtattcacag aaattgaggg cattactttt aaaagttgca
     3901 agaagattaa gcaatcaatc ttacccaaat aattcatcag gatttggttt tttaaattta
     3961 tcagatgtag atttgtacac tctatctagc ataaatcaag atttagaaac agaggatatt
     4021 ggatatagaa gtattaataa gtcatttatg gatgaggcaa ataattatat acccatagat
     4081 ggttataatg tacaaataca taatgggtta gagaaggaaa agtatataag taaaaatata
     4141 agtagacagt caggaatact atcaggaata gatgtagtcc atactcctga atttgaagaa
     4201 gaattagctg ggttaggtca gagtcaaaat tttttaaaaa taagtgattc attaggtgta
     4261 ctatctatag ataatacaga ctataatagc atacaacaag ttttacaact tccttcaatc
     4321 ataagaacta taccaactac aaagatgaca ttgcttggag aaattaatag aggtactttt
     4381 ggaggagtag ttgcaacaga agaaataggc gtaaatttct ttaaaaataa tcctaatatt
     4441 aatataacag gaagaggtac tctaatatca attgcagata caggaataga ctatctacac
     4501 cgagatttta tttatccaga tggtacctca aaaatagtat atctatggga ccaaacaaaa
     4561 gaaggaaatc caccagatgg tttttatatt ggtacagaat atacacgaga ggatataaat
     4621 cgagctattg cagcaaatga ccctagttta tctcaggacg aagttggtca aggaactatg
     4681 ttgagtggta tatgtgcagg gcttggaaat gtgaatagtg agtatgcagg ggtagcagaa
     4741 gattctgaat taatagtaat aaaacttggt aagatagaag gtttttataa tagtgcaatg
     4801 ttatttgctg catctcaata tgcatataat aaagcttttg aactgggaag accgttagtt
     4861 ataaatgtat ctttaggtac cagtagttta gctggtttaa ccaatagggt taatagtgaa
     4921 aaagcatttt ttactagagg tttatgtgta acagcaggag cagggaatga gggcaataca
     4981 caaacacata catctggaat aatatcacat gttggaggct ctgttgaagt tgagttagag
     5041 ttaaatgaag aagaggaaga attatcatta gaactttggt taagtaggcc agataaagct
     5101 gacgtaataa tagtatctcc tactggtgaa gaaagtaaaa ctgttggagt ttcaaattat
     5161 aataaagtaa caggtttatt tgacttagaa gggactgaat attctataac gtatatatat
     5221 ccaactactt tttctggaca gcaatttact aatgttactt taaagaatgc aaaaagaggt
     5281 gtatggaaga ttcgattagt aggggtttat attataacag ggagatataa cttatacctt
     5341 ccaaatagaa aacttttaaa aagtggaact agatttagag aggtagaccc tttttatact
     5401 ataaattatc ctgctattca agatgattta ataactatag gagcttacaa tactattaac
     5461 agtagtttat ggcaaagttc atcaagagga ccaactattg aaaacagatt aaaaccagat
     5521 atagtagcac ctggtgttaa tataatagct gcttatcctg ggaataccta tgcaactata
     5581 actggtacag cagcagcaag tgcacatgca gctggtgctg cagcaatgta ttttcaatat
     5641 acttttgttg atggtagata tccaaatcaa gcctatgttc aaaaaataaa aacgtttatg
     5701 caagctggag ctagaaagga ttcaaataca gtatatccaa atacaaattc tggatatggg
     5761 cttttggatg ttagaggaat gtttgatgtt ttaagatagg agggatttat ggaaaaatct
     5821 tattgtataa tttatcaagg tgatatagag tctgcactac aagaaaatgg aataaatagg
     5881 tatatggttt taaatagtca acttgcagta atatatgtac ctatagattt tgatgaaact
     5941 attctaaata atataataca ggttgcttgg tgggaagaat ctgcaccaat gagcagttta
     6001 attgaaataa ccaataatgt agataatgga gaaaccatta caacggctgc tggaactgag
     6061 tatatctatg aaaatccata taatgatata accggaagag gaattttatt agcagttata
     6121 gattctggta tagattattt gcatcctgat tttataaatg atgacggaac cagtaaagtt
     6181 ttatatttat gggaccaaga agcaaataca aatccacctc cagaaggttt tatttttgga
     6241 agtgaattta caagaagtga gttaaatata gccataaata gaaatgatgg aagtttgagt
     6301 caagataata taggtactgg aactttagtt tctggtatat tagctggaaa tggaagggta
     6361 aattcgaagt atagaggtat tactacagaa tcagacttaa tagtagttaa attaaaatct
     6421 tatataggta cttattatgc tggaaggata aattacagtg tttcagattt tttagcagct
     6481 ataacgtatg ttactaatat agcaagaaca gaaaatagac cactaataat aaatctgact
     6541 attggagtta agtcaggagc tgtagcaact acttcaatac tagatacttt taatatattg
     6601 agtagtgctg gtgtagtagt agtgagtggc gcaggaaatc aaggtaatac agatattcac
     6661 tattctggaa gatttagtag tgtaggtgaa gttcaagatg tgataataca ggatggagat
     6721 gactatgcac tggatataac actaaatact aatggtccag ataaagtagg tgcacagata
     6781 atatctcctt caggcgaagt tagtcatgac ataaggtatg ctccagactt ttatatatat
     6841 agaggaaaat ttaacttaga aaatactact tatgcaatga gatttattta tccatatatt
     6901 acttctggaa aagaaaattt ggaaataaga ttaagagata taaaacctgg agtatggact
     6961 ttaagattga cttcagaact tataataggt ggagaatatg atatatactt gccaaataaa
     7021 aatttgatag ctccagatac aaggttttta gaccctgatt cagtagctac aataactatg
     7081 tatgctgcta gtgatgatgt aattacagtt ggtacgttca ataataagac tgacagcatg
     7141 tggataggtt cttcaaaagg tccaatccga ggaagaggaa ttaagccaga tatagtagct
     7201 ccaggtgtag atataatatc tacatataaa aatggaacgt ataatacagg aacaggaacc
     7261 ggtgtgagca gttctatagt cacaggtgtt ttagctttac taatggaata tttggaaaaa
     7321 cagaataata taccaagatt atcattgttt acacaagttt taaagacata tttgatattg
     7381 ggagctacaa agcttgagat atatacatat ccaaatgtat cacaaggata tgggatttta
     7441 aacttaaaaa atacaattca acaaatagca aatactctat agataataat ctgcataaat
     7501 ttatagttaa ttaatagttc agataacaaa aaattgaatt agagtaaata taaaaattaa
     7561 aaaatagttt tatatgttgt atatataaaa taactatttt taac
//
LOCUS       DBGJFK010000116         7349 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.123, whole genome shotgun sequence.
ACCESSION   DBGJFK010000116 DBGJFK010000000
VERSION     DBGJFK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7349
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.123"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            146..1084
                     /locus_tag="ACOIAP_003436"
     CDS             146..1084
                     /locus_tag="ACOIAP_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HGZ2640308.1"
                     /translation="MNKRMKLIPYEINENPRGAKNKFPYGIKQMNVRGMWDEGYTGKN
                     IVVGIIDTGCDVSHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVIQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMGNKLAIMSGTSMSAPYVSGSLALIKEWARDEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNTGKR"
     gene            1598..2026
                     /locus_tag="ACOIAP_003437"
     CDS             1598..2026
                     /locus_tag="ACOIAP_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGZ2640309.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFIAEGVKSKGKTPEVLDVSLLKPS
                     DLKEENKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMREW
                     EERMQNAGAVIIGGEGITAMEEPDEEAKDECIELGKMLAE"
     gene            complement(2179..2973)
                     /locus_tag="ACOIAP_003438"
     CDS             complement(2179..2973)
                     /locus_tag="ACOIAP_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase/citrate lyase family protein"
                     /protein_id="HGZ2640310.1"
                     /translation="MEKYANMIKEKLNSGKVLCGVAVSLSDSVVSELIGISGYDFVWI
                     EGEHGALDRKDIQQHMIAAHAGGAASLVRLVNSDPDIVKPIMDMGTDIICFPFINTVQ
                     DAQKAVAACTYPPNGIRGYNPQRASYYGNMNYFDYVKNANNETLKMMLIEQKAGYDNL
                     EEIVKVKGVDIIALGPGDLSLDMGFSGYMDRIEIKDMISNATDICKKYKMPFVTFPSI
                     EKNSIETWVNIGSNMLCFAQDTTFITYVINQLLSFYNEIVPIKKQH"
     gene            3122..3490
                     /locus_tag="ACOIAP_003439"
     CDS             3122..3490
                     /locus_tag="ACOIAP_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGZ2640311.1"
                     /translation="MKYSMTDVSKITEISSSAIRFYEKKGLLLPINRKPSGVRYFYEE
                     DINRLMFIKELKNAGLSIKDIHECFHFCDMGDDTIDKRIQLFQQHKQNIKNKIYELEN
                     CMDRIDEKIYYLKVKKMCKK"
     gene            3805..4167
                     /locus_tag="ACOIAP_003440"
     CDS             3805..4167
                     /locus_tag="ACOIAP_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGZ2640312.1"
                     /translation="MYESRENYLETILILEKKNGIVKSIDIAKQLNYSKASVSRAIGI
                     LKEYGFIIMEVDGDIVLTEEGRKKAEEIYEKHILITKFLVNTLGVSFDIAEKDACRIE
                     HVISKETFEGIKKYLDKN"
     gene            4179..5834
                     /locus_tag="ACOIAP_003441"
     CDS             4179..5834
                     /locus_tag="ACOIAP_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PocR ligand-binding domain-containing protein"
                     /protein_id="HGZ2640313.1"
                     /translation="MMDFSESNDEVQKFDWGEVTWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKISIKEKSIIYCPPYSEHEIINTGKVDLVI
                     LITYVPHKFSSLRQLPIVFSENTIQELINVNIIENLANQISNILKLRISVYDSKHKEI
                     FETKKETKFCDICKSIKECNRKLAKGMNNDNFEKMYHCRYGISSLEIPIVLEENIVGY
                     IECGNFIIYKSIDIDNNLSKLSSSSDVDIKYISKVYNELSLIPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKIRKENIRLEEALKKANSKLLEEDYIINPIDMFN
                     NNLKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLIYNDVRDIIKEMIFVLSRTALRD
                     LEDLKLISYLINKYNKKISLVDSDEDLWGVLFEFSNECIDKNRAFWRKDKGNLIENIN
                     KYIQKYYKENISLNSISEVFFISPNYLSSIFNERNKVSITEYINLLRVEESKKYLLDR
                     SFSISDICKKVGFNNSSYFSQIFKKFNNVTPNEYRKNILDNEH"
     gene            5895..6647
                     /locus_tag="ACOIAP_003442"
     CDS             5895..6647
                     /locus_tag="ACOIAP_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGZ2640314.1"
                     /translation="MFAIIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKVNNDLLKKLVPFTIVGSILGVRCVLSISEDILNVLV
                     VVMILIVAIYTFTSKNLGQEDNFESINNKNLRLGMLMAFIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYIGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            6858..6992
                     /locus_tag="ACOIAP_003443"
     CDS             6858..6992
                     /locus_tag="ACOIAP_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640315.1"
                     /translation="MNISRRAMKIIELAQKIANKRGVTVQDAWNDAMKEYKEKYEYVA
                     "
     gene            complement(7163..7234)
                     /locus_tag="ACOIAP_003444"
                     /pseudo
     CDS             complement(7163..7234)
                     /locus_tag="ACOIAP_003444"
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2933 a          708 c         1201 g         2507 t
ORIGIN      
        1 atatacaata aaatatgatt cctaaaaata aaaaatatat cataaatata aataagtaga
       61 tataggtttt aatttgattt ataaacctat tataaaataa aatttatgat ttttataagc
      121 aataaaattt ttaggaggat atgtgatgaa taaaagaatg aaactaattc catatgaaat
      181 aaatgagaat ccaagaggtg caaaaaataa gtttccctat ggaataaagc aaatgaatgt
      241 taggggaatg tgggatgaag gttatactgg taaaaatatt gtagttggta taatagatac
      301 aggctgtgat gtatcccatc ctcttttaaa aggaaaaata attggtgggg caaattttag
      361 tgatgacagt aatggaaata aaaatatata tgaagatttt aatgggcatg gaactcatgt
      421 tgcaggcatt atagctgcat ctaattataa taatgaagtt atgggagtag ctccagattg
      481 taaattatta atagcaaaag cattaaataa agatggtact ggaacatatc aaagtataat
      541 taatgctatt aactttgctg taaataacaa ggttgatatt atatctatgt ctcttggagg
      601 aaacaaagat gataagaatt taaaaaatgc tgtcatacaa gcagtaaaaa ataatatttc
      661 tgtagtgtgt gcagcaggga ataatggaga tggagactct agtacaagtg aatatagcta
      721 tccagcaagt tatgctgagg tgatagaagt aggtgcaata aatgagaact atttagttga
      781 aaagtttagt aattcaaata ctacaataga tttggtggct ccaggaagaa atattatatc
      841 aacttatatg ggtaataaac ttgctattat gagtggtact agtatgagtg caccatacgt
      901 atcaggctca ttagcactaa ttaaagaatg ggcaagagat gagtttgaaa gagatttaga
      961 tgaagctgaa ttgtatgcac aattaataaa atgtacgagg gcacttggaa tacctagaac
     1021 agaacaagga aatggatact tatatttaaa tctttataaa tacaagaata ctggtaaaag
     1081 ataatttata attttataat aaaataaata gggtatatag ttaacgcaaa tgataaaaat
     1141 taactaagtg tatattttga aatagatata tgaaaatatt taataataag gtctatagac
     1201 ctgttatgca attagaataa taaaaaatat acagtattat agatagcaca tctgaagaaa
     1261 gatgtgttct tctatatgtc tgtatagatg ctgtatataa aaggtaaatt ctagattgaa
     1321 gttaagaagg tataagatta tttataatac gaacaagaat attaagcgtg agaaatattc
     1381 ttataaaaga tttagaaata taatgtgata ttataggtaa ataaagagta tagaaaataa
     1441 atgatatata ttatcaatag gtattgaatt tcaaaatcat ttgtgataat atatatttag
     1501 aaaaataaga gattttagat aaaggaattt tttattttta gaatttagtt agcgattgct
     1561 aactttcgat taattaaaaa tactacagga ggtaagaatg agtaaaatat atattgttta
     1621 ttggagtgga acaggaaata ctgaaaaaat ggcaaatttt atagctgaag gtgtgaagtc
     1681 aaaaggcaaa acaccagagg ttttagatgt aagtttgtta aagccaagtg atttaaaaga
     1741 agaaaataaa tttgcattgg gttgcccatc tatgggagca gagcaactag aagaaggata
     1801 tatggaacca tttgtgtcag aattagaatc tatggtatca ggtaaacaaa ttggattatt
     1861 tggttcatat ggttggggaa attgcgaatg gatgagagaa tgggaagaac gtatgcaaaa
     1921 tgctggtgcg gtaattatag gtggtgaagg aattacagca atggaagaac cagatgaaga
     1981 agcgaaagat gagtgtatag aattaggcaa aatgttagct gaataaattt gtatactata
     2041 aaaatagtat aagtagtaac taatgataat agcagtgtat aatactaaga gagactaata
     2101 ttatgataca taagaaaaca cccttaatag agatagataa aatattagtc tcttttagta
     2161 taaaattaga tttataattt aatgttgttt tttaattggt acaatctcat tataaaaaga
     2221 caataattga ttgataacat aagtaataaa ggtagtatct tgtgcaaaac aaagcatatt
     2281 tgatccaata ttaacccatg tttcaatact gttcttttct attgaaggaa aagtaacaaa
     2341 tggcatttta tattttttgc atatatcagt ggcattagaa atcatatctt ttatttcaat
     2401 tctatccatg tatccagaaa atcccatgtc caaggataag tcaccaggac ctaatgctat
     2461 aatatcaaca cccttgactt ttactatttc ttcaaggtta tcataacctg ccttctgttc
     2521 aattaacatc atttttaatg tttcattgtt tgcgtttttg acatagtcaa aataattcat
     2581 attcccataa taagaggctc tttgaggatt gtatcctctt ataccgtttg gaggataagt
     2641 acaagctgct actgcttttt gtgcatcttg tactgtatta ataaatggga aacaaataat
     2701 atctgttccc atatccatta taggcttaac aatgtcaggg tcactgttta ctaatcgtac
     2761 caaagaagca gcaccaccag catgtgcagc tatcatatgt tgctgaatgt ctttacgatc
     2821 taaagcacca tgttctcctt caatccagac aaaatcatat ccagatatac cgattaactc
     2881 acttacaact gaatcagaca gtgaaacagc tactccacat aagacctttc ctgaatttag
     2941 tttttcttta atcatatttg catatttttc catatacatc atcctttctt ttgtcagttt
     3001 acttttacac ttcaaagaat acaacttcaa tctaacttga agtcaatact tttttgttga
     3061 ctacagtata aggtattttt ataatattct tattcctata aaatttatgg aggtaaagat
     3121 tatgaaatat tctatgactg atgtatctaa aataacagaa atttcttcat ctgctattcg
     3181 attttatgaa aaaaaaggtt tattacttcc tatcaataga aaaccaagtg gtgttcgcta
     3241 tttctatgaa gaagacataa atcgtcttat gtttatcaaa gaattaaaaa atgctggttt
     3301 atctattaaa gatatccatg aatgctttca tttttgtgat atgggagatg acacaataga
     3361 taaaagaatc caattatttc aacaacataa acaaaacatt aaaaataaaa tatatgaact
     3421 agaaaattgc atggatagaa tagatgagaa aatatattac ttaaaggtaa aaaagatgtg
     3481 taaaaaataa tccttataga ataaggaaat aattttttga tttttctaat ataagtagta
     3541 aattcaaatg gcaacatttg agaaaagatt ttttacaata tatttctacg aagaattgga
     3601 caatgttcta tataactatt tatctataca atgaaaagaa aattatgata gtatatatta
     3661 atgtaagtag taaaaatatt tttgtttgta aatatgagta tttttaaaca ctataaatat
     3721 gaatgttata atatatactt atacttttct aataattatt attaaaagaa tataatagag
     3781 ttgttatata tggaggatgt taaaatgtat gaatcaagag aaaattattt ggagacaata
     3841 cttattttag aaaagaaaaa tggaattgta aaatcaattg atatagccaa acagttaaat
     3901 tatagtaagg caagtgtaag tagagcaata ggaattttaa aagaatatgg ttttattata
     3961 atggaagtag atggtgacat tgttttaacc gaagaaggaa gaaaaaaagc agaagaaatt
     4021 tatgaaaaac atattttaat cactaaattt ttagtaaata cattgggtgt ttcatttgat
     4081 atagctgaaa aagatgcatg tagaatagaa catgttataa gtaaagagac atttgaagga
     4141 ataaaaaaat atttagataa aaactaagag gtgaatttat gatggatttt agtgagtcaa
     4201 atgatgaagt acaaaaattt gattggggag aggttacatg gatacatgaa ccatcaaaaa
     4261 cacaatttaa tagacttagt gctggaattg taaggttctt tccaggcaac tgtcaagaaa
     4321 aacattttca tttaagtgaa gaacagcttt tatatgtgat tcagggagaa ggaatacaaa
     4381 tcattgatgg caaaaagatt agtataaagg aaaaatccat aatttattgc cctccatatt
     4441 cggaacatga gattataaat actggtaaag ttgatttagt aatattaatc acttatgttc
     4501 ctcataaatt ttcaagttta agacagttac ctatagtatt ttcagaaaat actattcaag
     4561 agttaattaa tgtaaatata attgaaaatc ttgcaaatca aatatctaat atattgaagc
     4621 ttagaatatc tgtatatgac tcaaaacata aagaaatatt tgagactaaa aaagagacta
     4681 aattttgtga tatttgtaaa agtataaaag agtgtaatag aaaacttgct aaaggtatga
     4741 ataatgacaa ttttgaaaaa atgtatcatt gtaggtatgg gatttctagt ttggagatac
     4801 ccatagtatt agaagaaaat atagttggat atatagaatg tggaaatttc ataatataca
     4861 agtctattga catagataat aatttatcta aattatcaag cagttcagat gttgacataa
     4921 aatacataag taaagtttat aacgaacttt cattaattcc aaagagtaga ttatatgtgt
     4981 taaaagagaa tttattaatg atgtctgaat ttattcagga aatagctaag aggaattttt
     5041 ttgaaaatca acttagtata aaagatgagg aaatattgaa gattagaaaa gaaaatataa
     5101 gacttgaaga agcacttaaa aaagcaaata gtaaattatt agaagaggat tacattatta
     5161 atccaataga tatgttcaat aataatttaa aagaatatcc ctttgaatta gaactttata
     5221 ttgaaaaaga aattaaaaat atgaatttag aaggagttta taatctaata gatacaaata
     5281 aattaatata taatgatgtt agagatatta ttaaggaaat gatatttgtt ttatccagaa
     5341 cagcacttag agatttagaa gatttaaaac ttatatctta tttaataaat aaatataata
     5401 aaaaaatatc acttgtagac agtgatgaag atttatgggg tgtattattt gaattttcta
     5461 atgagtgtat tgataagaat agagcatttt ggagaaaaga taagggaaat ctgattgaaa
     5521 atataaacaa atatatacaa aaatattata aagaaaatat aagtttaaat agtatatctg
     5581 aggtcttttt tataagtcca aactatttga gttctatttt taatgaaaga aataaggtct
     5641 caataactga gtatataaat cttcttaggg tagaagaatc taaaaaatat ttgttagata
     5701 gaagttttag tattagtgat atttgtaaga aagtaggttt taataatagt agttactttt
     5761 cacagatatt taagaagttt aataatgtaa ctccaaatga atatagaaag aatatactag
     5821 ataatgaaca ttaaataaaa gtatataaca tatatattgt aagaaaaatt gaaagagaat
     5881 gatggaggat ttttatgttt gcaattattt ttttatgtat aggagggttt ttagcagctt
     5941 ttgtagattc tatagcagga ggtggaggac ttataagtat gcctgttctt atggcaattg
     6001 gagtaccagt acatcttgct attggtacaa ataaatttgc agcgtcagca ggatgtataa
     6061 gtagcgctta tagatatgca aagtctggaa aagtcaataa tgacctttta aaaaaattag
     6121 taccatttac tattgttggt agtattttag gtgtgagatg tgtattatca ataagtgaag
     6181 atatattaaa tgttttggtt gtagttatga ttttaatagt agctatttac acctttactt
     6241 ctaaaaattt aggacaagaa gataattttg aatctattaa taataaaaat ttaagattag
     6301 gtatgctcat ggcttttata atgggttttt atgatggttt ttttggtcca ggtacaggaa
     6361 cttttttgac ttttggattt ataaaaatat atggatatga ttttttacat gcttctgcaa
     6421 atacaaaaat attaaactta acaagtaata taacttcatt attattattc atgataaatg
     6481 gtcaagtcga ttataagatt gctatagtgt ttgcattagt gatgataatg ggagcttata
     6541 taggtgctaa agttgctata aagaaaggtt caaagatgat aaagccaata tttttagtaa
     6601 tggcattgtt tatggtcgta aaattggtat atcaaacatt agtttagttt atagaacttt
     6661 taaatttata agtaactgca aatcttttag atttaaccta atcatatagt tttataaaaa
     6721 ttctaattat cttctaatat agttcatata taatacacat ataaattgta atattacaat
     6781 agaaggatta tatatcataa aaatataatc ttgatttatg tgtatgaaat atatggtaat
     6841 ttgtaggagg aatgtttatg aacatatcaa gaagagctat gaagataatt gaactggcac
     6901 aaaaaattgc taataaaaga ggtgtaacag tacaagacgc ttggaatgat gctatgaaag
     6961 aatataaaga aaaatatgaa tatgttgcat aaaatatgcg ttatatttta aatataagaa
     7021 aatataaaac aaaagagctt atcttaaaat aggattgtac tgagactaaa aagttagatt
     7081 ttatacagga atggaatttt cattcctgta tttttaattt tatgcaattt tatattcata
     7141 ttcaaatata cgtttaacaa ggctattcta atttaatttt tttaattctt ttgttattat
     7201 aatagtaaat atattctact atagttgtat ctaactaata gaagttttta tgtatttttc
     7261 tacagtatgt tttttgcttc attcttctct atttaaatag aatttaacta ccttttaaat
     7321 taggttcaac taattttaat ttgaaatca
//
LOCUS       DBGJFK010000117         7142 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.124, whole genome shotgun sequence.
ACCESSION   DBGJFK010000117 DBGJFK010000000
VERSION     DBGJFK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7142
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.124"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..765)
                     /locus_tag="ACOIAP_003445"
     CDS             complement(<1..765)
                     /locus_tag="ACOIAP_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HGZ2640316.1"
                     /translation="MNCTNKKILILSLSMITILASVGEVNALEVKNNSNLEKQTIKET
                     VVPELVGLKMQEAFPDENFRKYIFGILVTLDISDIRDDTTINSEIKQKIEGIKDLSLE
                     YESIKDLTGINYFTGLEKLYCSSNELKKLDLSKNTKLEELNASSNKLKTINLNGSEKL
                     KTLLCNDNELSNLDVSKNTKLKYLYCDNNRLEKLDITNNKNLVGYSWGNQKEPEKPSE
                     PEKPSGGGSYTPAPIVTKINSLVGSDRYATSIKISKQ"
     gene            complement(1064..1321)
                     /locus_tag="ACOIAP_003446"
     CDS             complement(1064..1321)
                     /locus_tag="ACOIAP_003446"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640317.1"
                     /translation="MYKHTIVYDGEVDKIPATVLGWGYGSNKILICNIKDYVPGRTEN
                     LYVVVGGACEKIGSITKENYTMIKGSDRFDTLYKVLDFINR"
     gene            complement(1372..1593)
                     /locus_tag="ACOIAP_003447"
     CDS             complement(1372..1593)
                     /locus_tag="ACOIAP_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640318.1"
                     /translation="MNKYNKTLKKNKIFQGISRKATFFDNSPMKNSFGVMKRECIIKK
                     YKQLFESFFVIIKRIMRGLRNLDMKVLLS"
     gene            1955..2305
                     /locus_tag="ACOIAP_003448"
     CDS             1955..2305
                     /locus_tag="ACOIAP_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HGZ2640319.1"
                     /translation="MIQKKFFMGFCGFIGFLSLRYFSSGNIADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKSAMAFTGQFAIIELFILWCITIVSRNVELMCVLLSIAYAIT
                     LNVYAIKLYILEEK"
     gene            2307..2507
                     /locus_tag="ACOIAP_003449"
     CDS             2307..2507
                     /locus_tag="ACOIAP_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2640320.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     regulatory      2790..2879
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            2933..3109
                     /locus_tag="ACOIAP_003450"
     CDS             2933..3109
                     /locus_tag="ACOIAP_003450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640321.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFIIEYGEKVVE
                     SCLHQVMVLVSKYN"
     gene            3334..3534
                     /locus_tag="ACOIAP_003451"
     CDS             3334..3534
                     /locus_tag="ACOIAP_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011723062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGZ2640322.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            4145..4957
                     /gene="modA"
                     /locus_tag="ACOIAP_003452"
     CDS             4145..4957
                     /gene="modA"
                     /locus_tag="ACOIAP_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HGZ2640323.1"
                     /translation="MFKKFSVLILSMIISLSITACNSKENKANNESNAKVTTANDSKE
                     KETLFVYSGAGLKKPMDEIAQKFEKENNIKIEYSYAGSAQLIAQIETSHKGDAFIVGS
                     EPIYSKAFEKKLVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNRDGVKLIFGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIASDEAKQIFKKYGFEPVK"
     gene            4967..5758
                     /locus_tag="ACOIAP_003453"
     CDS             4967..5758
                     /locus_tag="ACOIAP_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640324.1"
                     /translation="MKNKFFTILLTGFFAVVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKILKLDFVFTKQGIILAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFKFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            5760..6455
                     /locus_tag="ACOIAP_003454"
     CDS             5760..6455
                     /locus_tag="ACOIAP_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2640325.1"
                     /translation="MLKIRNLSLDLPNFKLQENSLNINNHEYFVLLGSSGSGKTLFLE
                     TLAGRYPSAKGSVSFKKNLISSLPPENRNIGFVYQNFELFPNMNVEDNISFPLKLRKI
                     PIDEQILKVNHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKHKGESFFYEYI"
     gene            6442..>7142
                     /locus_tag="ACOIAP_003455"
     CDS             6442..>7142
                     /locus_tag="ACOIAP_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF364 domain-containing protein"
                     /protein_id="HGZ2640326.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIIGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLYDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEICAKNFPKFIKREFDNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTVSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNIL"
BASE COUNT         2683 a          914 c          928 g         2617 t
ORIGIN      
        1 ttgtttactt atttttattg aggtagcata tctatcagaa cctactaaag aatttatttt
       61 tgtaactatt ggagctggag tataagaacc tcctccagac ggtttctctg gctcagatgg
      121 tttttctggc tctttctggt ttccccaaga gtaacctaca agatttttat tgttagtaat
      181 atctaatttt tctagtctat tgttatcaca atataaatat ttaagttttg tatttttact
      241 tacatctaga ttgcttagtt cattatcgtt acacaataaa gttttaagtt tttcacttcc
      301 atttaaattt attgttttta atttattaga actagcgttt aactcttcta atttagtatt
      361 tttacttaaa tctaatttct ttagttcatt agaagaacaa tataattttt ctaatccagt
      421 aaaataatta attcctgtta aatcttttat agattcatac tctaaactta agtcttttat
      481 tccttcaatt ttctgtttta tttcgctatt tatagtagta tcatctctaa tatctgaaat
      541 atccaaagtt actaaaatac caaaaatgta ttttctaaaa ttttcatctg gaaaagcttc
      601 ttgcattttt aatcctacta actcaggtac aacagtctcc tttattgttt gtttttctaa
      661 attgctatta tttttgactt ctagtgcatt tacttctcct actgaagcca aaattgttat
      721 catagataat gataaaataa gtattttttt attagtacaa ttcacttaat attcctccta
      781 taaaaataat acacatttcc tgattttatc atctcttgat aaatttagca ataattcaaa
      841 aatatatctt atctatgatt aattatttat attaaaataa ttgaaatatt tttatgattt
      901 taataaaaaa ttatttatta aacataaatt attatatttt catatactct tacttacaaa
      961 tatcttctta tattaacttt atagttatac aaataacaaa aattgtcaga tataaaaagc
     1021 tagaaaaagg aaggtaacaa cctactagtt gctacctttt aatctatcta tttataaaat
     1081 ctaatacttt gtaaagtgta tcaaatctat cactaccctt tatcatggta tagttttctt
     1141 tagttataga acctatcttc tcacatgctc caccaacaac aacataaaga ttttcagttc
     1201 ttcctggtac ataatctttt atattacata ttaaaatttt atttgaacca taaccccaac
     1261 caagcacagt tgcagggatt ttatcaactt caccatcata aactattgta tgtttgtaca
     1321 tctgtttaac tccctcatta tttatatttt tatttaatac accttctaca attaacttag
     1381 caataccttc atatctaagt ttcttagccc cctcataatc ctctttatta ttacaaaaaa
     1441 actttcaaat aattgtttat atttttttat aatacattct cgcttcatta ctccaaatga
     1501 atttttcata ggagagttat caaagaatgt agccttacga gatatacctt gaaatatttt
     1561 atttttctta agtgttttgt tatacttatt cattttatat ggccaacctt ggtttgagtt
     1621 aaaagtcctt ctataaggac aatcctttgt aatattgata gctttattta aaacatcact
     1681 attgatttaa agttagccat atatcagaca ctgaatgaca taacttctcc ttcttctcta
     1741 tttaaataaa atttagctac ttttaattta aatttaaaat cgtatttagt catacataaa
     1801 cacctcaatc attagatttt tggtctagta attatggtac attacaaata ttgtataaca
     1861 ctgcttttat attgacaaaa aaataaaaaa gagatatatt tatatcataa agatacaaat
     1921 atatctcttt ttaaaatact aaggaggata agaaatgatt cagaaaaaat tttttatggg
     1981 tttttgtggt ttcattggat ttttaagtct tagatatttt tcatctggta atattgctga
     2041 ccttacatat attggctttt ttgctttttt ctcaaacttt attatagcaa aaataaacgg
     2101 tgataaagca gatgaaaggt atgtacaaga tgaaaaatca gctatggcat ttacaggaca
     2161 gtttgctatt atagaattat ttattttatg gtgcattact atagtgtcta gaaatgtaga
     2221 attaatgtgt gttttactat caattgcata tgcaattact ttaaatgttt atgctataaa
     2281 actttatatt ttagaggaaa aataacatgc ccaaattcat ttgtaatcta aaaaaataca
     2341 gacaattaaa agaattaact caagaacaat tagcagaaaa agtaggagtt agaagagaaa
     2401 ccattatgcg tttggaagca ggtaagtata atccttcttt aaaattagcg atagatatat
     2461 caaaaatagt agatactcct attgatgaat tgtttatttt tgattagttt ttgcattatt
     2521 aaaaacacgt tttaaattca aacttaaatt caatttttag tcactcctcc cagaggggct
     2581 ttttattttt ttaataattt attagttaag taaaatatta aactggcaac tgaatttact
     2641 agtatacctt gtaaaaaatt atcaatgtgt gttcacctct ctttttaata ttgaaaaaat
     2701 aatttaacat taatatataa atttattaat ttttcagcta gatatgttga ataataacta
     2761 attctattgt attattagtt tgtagaataa aactaaatcg gcaaaactag agaaatttag
     2821 tgacgcaaag ctatagggac taacgcttat aaaataagtt atgtcagcca gttgccaaaa
     2881 agatattttc tttttgtttt tcatgaaagt tttttaggga gataaataca ttatgtttag
     2941 agataaaatg gataaatgta cacatatgtt aactgcttat attggtagtt catatgatta
     3001 ttgtgatttt atagatacac agttagatga ttttataata gagtatggag aaaaagttgt
     3061 agaatcttgc ttgcatcaag tgatggtatt ggtaagtaag tataattaga cagatttttt
     3121 tctagaaaac cctttttagt tttatctaca tttacattaa tatattggta atataaaatg
     3181 tttaaattta ttttcatatt aagaataaat aaaaatgtta actaaaaatt ataattaaat
     3241 agacatttct attaatctat gatacaatag tatttgtggt aatacacaag taaatcaagt
     3301 atatcttgat ataggttaat aggagtattt ttaatgaata atggaatagt aaaatggttt
     3361 aataatgaaa aaggatttgg atttatatca atggaaagtg gagatgatgt atttgctcat
     3421 ttctcagcta tacaaacttc aggatttaaa tcattagaag aaggtcaaaa agtaagcttt
     3481 gatatagtta aaggcgctag aggtcctcaa gcagaaaata taactatatt ataatatata
     3541 gatttttcgg aaagactctt ttgagggtct tttttttatt gataatattc tgtaaataag
     3601 taaaaaaatc ccttaataag agaatactta gtctaaacac tttttataaa ataagtctca
     3661 caaaaaaata tttataaagt atatacttaa acttacaaat atttttttag ttaaactata
     3721 taatagaata atttaattgt aacataccaa aactttcaac taactcctaa acacatatac
     3781 tttctcttct attcaattct aataaattat caataaaaag taattaaaac atatttatat
     3841 atttcagagc tatatttgtt aatgaaatat gtataaatat aaaataaatt catttaaaaa
     3901 ataaaaagac tacaatcgat taatttaaaa atagttttta aatttaaaat actttaaagt
     3961 attaataaaa gttaaaaatg aaataactct ctatgaaaat gacattatag atagattttc
     4021 tcttaaccac acatgacaaa acataacaaa acattataaa acataacaaa agcttagaca
     4081 tcgttttctt agtatgatat actaaaaaaa gaatttacac taatttacca agggggaata
     4141 tattatgttt aaaaaatttt cagtactaat tttatctatg attatttcat taagtattac
     4201 tgcatgtaat tctaaagaaa acaaagcgaa taatgaatct aatgctaaag tgacaacagc
     4261 taatgactca aaagaaaaag aaactctttt tgtatattca ggtgcaggtt taaagaaacc
     4321 aatggatgaa atagctcaaa aatttgagaa agaaaataat atcaaaattg aatatagcta
     4381 tgcaggctct gcacagctaa tagctcaaat tgaaacaagt cacaagggag atgcatttat
     4441 tgttggttct gaaccaattt actcaaaggc ctttgaaaaa aaacttgtag gtgaacataa
     4501 aacagttgca catcatactc ctgcaatagt tgtacctaaa gggaatccag ctaatattca
     4561 aaaactggaa gacttaaata gagatggagt taaacttatt tttggagaca aagagtctaa
     4621 tgccataggt aagactacgc aaaaaatact tgaaaaaaat aatttaaaat ctataaatga
     4681 taatgttgtc tctacagctg caactgtaaa tgaaatgatt gtacagttaa catcaagtaa
     4741 agcagatgct acaatagcca caaaagattc agtctttggc aatgaggatg tagaagttat
     4801 agaaattgct caagataaaa acatagacca actcatatca gcaggaatcg taaactatag
     4861 tgataaaaaa gatttagcta ataaatttat aaactacata gcatcagatg aagctaaaca
     4921 gatatttaaa aaatatggtt ttgaacctgt taagtagtga ttaaacttga aaaataaatt
     4981 ttttactata ctacttactg gattttttgc tgtagtcttt ttatttattg tatcaccact
     5041 tcttatgtta atcattaaag ggataagtta tgttcctata tgcttaaaat cagtggaggt
     5101 acagtatgca ataacactta gtattaaaac atctttaata tctactatag tatgcctttt
     5161 gttagctatt ccagtagcat actttttaca tattactaaa ttaccattta aaaaactgat
     5221 tatacagata ataaatctcc ctatgtctct tccccaccta gtatcaggaa ttgctctctt
     5281 gcttttgttt ggaagaatgg ggattggaga ttccatttac aagattctta agcttgattt
     5341 tgtatttaca aagcaaggta taattttggc acaagtattt gtaaatcttc cacttactat
     5401 taaaatactt cacacttcac taaatgaaag taacgaaaag atgatatttg ttgcacgtac
     5461 tcttggatgt aatagttggg aagcatttaa atttataatt cttccaaatc taaaaactgg
     5521 aatcatatct gcaactgtaa tgacttggtc aagagcactt ggtgaatttg gtgcagtagc
     5581 tatgatagca ggttctacac gtatgaaaac tgaaattatt cctacatcta tatatttaaa
     5641 tatgtctact ggtgatatag atattgcaat tggaatagct gtaattttga tatttatctc
     5701 acttacatgc ttgatgcttt ttgagatatt ttttaataga gaggttgata aaaattaata
     5761 tgttaaaaat aagaaattta tctcttgatt tacctaattt taaattacaa gaaaatagtt
     5821 taaatattaa taaccatgaa tactttgttt tattgggatc tagtggctca ggtaaaactc
     5881 tatttctaga aacattagca ggaagatatc catctgctaa aggaagtgta tcatttaaaa
     5941 aaaatttaat atcaagctta cctccagaaa atagaaatat aggatttgtg tatcaaaatt
     6001 ttgaattatt tccaaatatg aatgttgaag ataatataag ctttccactt aaattaagaa
     6061 aaatacctat agatgaacag attcttaaag ttaaccactt gtctaaatta atgcagatag
     6121 aggatataaa aaatagatat cctaaaaatt taagtggagg ggaaaagcaa cgagttgctt
     6181 ttgcacgtgc tttaatagct gaacctgata tattactttt agatgaacct atgagttcat
     6241 tagattatat tacaaaaaaa catataagca aaattttgaa ggatgtctac ataaaataca
     6301 aaccaacggt gattcatgtt actcatgata tttctgaagc aatgtttttt gctcataaga
     6361 taggaataat gaacaatgga aaaataaatc atatttttga tttaaatgaa gaaataaaac
     6421 ataaaggaga atcttttttc tatgaatata tttgatattt tgagagatta tctattagta
     6481 caagtagata aatataattt aaatatggat atgataagta ttgtatccaa atcgctatct
     6541 tcaaaagaag caattggaaa tactaagcgt aaagattttc caattataat tggtaaagaa
     6601 ataatgcttg aagctgactt taaaggagct aaaggacaag catttacttc tactccatct
     6661 acgtttgaag gttctttaaa agatatatta tcattagatt tatatgataa tcctcatgac
     6721 agaagtcttt ttatagcatc attaaatgct gttatgaaat acttaggtaa gacggataga
     6781 acgattcatt gtaaaaataa tgaaccagag atatgtgcaa aaaacttccc taagtttata
     6841 aaaagggaat ttgataaccc aaaagtagca attataggat atcaaccagc cataattgat
     6901 aatattaagg actttttcga aacaagagta ttagatttaa atcctgaatt tgtagatact
     6961 attcagtata atgttaagat tgaagatggt atacgagatt atgaagatgt aatatcttgg
     7021 gctgatttag tgatttgcac agtaagtaca ttatgtaata actcaattat aaattttcta
     7081 tcacttaata aaccagttta ctattatggc actacgatag ctggtgcatc aaatatttta
     7141 tg
//
LOCUS       DBGJFK010000118         6769 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.125, whole genome shotgun sequence.
ACCESSION   DBGJFK010000118 DBGJFK010000000
VERSION     DBGJFK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6769
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.125"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            136..621
                     /locus_tag="ACOIAP_003456"
     CDS             136..621
                     /locus_tag="ACOIAP_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HGZ2640327.1"
                     /translation="MISELMLKNFGESSINFKTKIKLNLREKPDLNSLKLKSIPGGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNDSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKIITTIPDGFKVEVCYNVGKWARVNIDKNEKRYSGYVYNQYIEEYLG
                     L"
     gene            959..1366
                     /locus_tag="ACOIAP_003457"
     CDS             959..1366
                     /locus_tag="ACOIAP_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640328.1"
                     /translation="MNKKKNLIGMAISFLLIISIINPLQVEAETIIESSVYISSIQEN
                     CTYNNTKFKTIKSRSRHKISKSNKSKVKLKKRSIRTKKYGYQTINKYKIRNARRHNIL
                     TKLILLIIVIFIVIILVILIFIKRKKKSFTKNN"
     misc_binding    1795..2058
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2210..2761
                     /locus_tag="ACOIAP_003458"
     CDS             2210..2761
                     /locus_tag="ACOIAP_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HGZ2640329.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNREDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMHISYKMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
     gene            3590..5026
                     /locus_tag="ACOIAP_003459"
     CDS             3590..5026
                     /locus_tag="ACOIAP_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HGZ2640330.1"
                     /translation="MKFYKRILTLILSISFVFANIQLANAISSVEKIQGKNKYEIAGK
                     IADKTAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKSPIILTNGQSIPFSTSGLKSYAIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHEPMVLVNDGSNKSV
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGIVKNIKPTTRTIKDGMYKVGKDIS
                     AGEYLITSNSGSYDSYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMI
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNNSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
     gene            5277..6713
                     /gene="miaB"
                     /locus_tag="ACOIAP_003460"
     CDS             5277..6713
                     /gene="miaB"
                     /locus_tag="ACOIAP_003460"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HGZ2640331.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPNMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESMNSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERIRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPE
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHERFNRVLEAVNRISAEINDGYKNRIVEVLVEGRSKNNENKLSGRTRQNKLVNFEGG
                     NDDLIGKLVMVEITEPRTFSLNGILVND"
BASE COUNT         2884 a          617 c         1040 g         2228 t
ORIGIN      
        1 ctatagggac taaaatcttt atataataaa ggtcatgtca gccagttgcc aaaaagataa
       61 tgattctttt tgttaaaaat atttttagag ttatatattt taataactta atatttggca
      121 agaggagggc ttaagatgat atctgaatta atgttaaaaa attttggaga atctagcatc
      181 aattttaaga ctaaaattaa attgaattta agagaaaaac cagacctaaa tagtttaaaa
      241 ttaaaaagta taccaggggg taaaattgtt aagttaaaat gtgtagatgg aatatgggca
      301 gaagttgaga gtaattatga caaaggctgg ttactttata aatatttaga aagattaagt
      361 aatgctaaaa atgatagtaa tgatacaata aaaaatagaa aaaagaatta tataggaaat
      421 ataagaacaa atggattaag tttagaactt agaaatgata gaacattaga atctaaaatt
      481 ataactacaa ttcctgatgg ttttaaagtt gaagtatgtt ataacgttgg gaaatgggca
      541 agagttaata ttgataaaaa tgaaaaacga tattctggat atgtatataa tcaatacata
      601 gaagaatatt taggtttata atatgatact agtgagcttt aaatatatta ataaattaca
      661 aaaaagaatc cctttaaagg ggttcttttt ttgtcgaaac attattatag aactaaagag
      721 aaaaaaataa tttattttta ctgtaaagta attataaatt taattgaaaa tagatttaat
      781 ttatacttta tatataaagt ttcataaatt aatactactt tgaaaaattt tagttatgat
      841 aataaaaata acattaaaga taataaaata tataagaaat ttgaaaaaat ttatgatttt
      901 tagttatata tgtatatatt ataatgaagt agataaaaat ttttataagg gggaaaatat
      961 gaataagaag aaaaacttga ttgggatggc tatatctttt ttacttataa tcagcatcat
     1021 aaatccatta caagtagaag cggaaactat tattgagtct agtgtctaca tttcttcaat
     1081 acaagaaaat tgtacatata ataatactaa atttaaaact attaaatcta gaagtagaca
     1141 taaaattagt aagtctaata aaagtaaagt aaagttgaaa aaacgaagta taagaactaa
     1201 aaaatatgga tatcaaacta taaataaata taaaatacga aatgcaagaa gacataatat
     1261 tctaacaaaa ttaatattgt taataatagt tatatttatt gttataattt tagtgatact
     1321 aatatttatt aaaagaaaga aaaaaagttt tactaaaaat aattaaaaga atatcatttt
     1381 tctaattatt attatttttg ttaataacat tatgtaatta aaacagagta gtattctgtt
     1441 tcaaagtagg tatataaata atacagaaat gagtattaaa tgatggtaaa tgagatgaat
     1501 ttttgataaa tgtacttaat taactttgaa gaatttagtt cctcatgcat caaaatataa
     1561 aattacatca ataattattc ataaaattaa taaaggcaga attagagcta aaaatcagat
     1621 tattagacta ttaaagtaat tattcataga attttgtatg tggaaagaaa tgtatagtgt
     1681 aatttacttt ttttataaaa aaatagatta caaaatatat tttttataaa aagtgttgac
     1741 attttttaga aaaaagaata tcattatttt aacaacaaaa tttaatacaa taaattaaat
     1801 cctatgacaa ggaagagtag ttaaatttag gttcagtata gagagctgag gatggtggaa
     1861 tcttagcgag aaaaaatttg atgaatggcc cttagaggaa taaattgaaa tcatagtttt
     1921 gagagtagac tttatcgtca gtcgcacgtt atagcgaata aggtatgtaa gtacctgata
     1981 atgagatata tgaaaattga attttatatt aatttttata taatttaggt ggcaacgcgg
     2041 ataatctccg tcctattagt ttaggacgga gtttttttat tttactgaaa atttaaaaga
     2101 tagaaggtgg tgaaaaagat gttatgaatt tccaaagcta aagatgatga tatagtaggt
     2161 tggcaaaaaa ataaattgaa aattaaaaaa ataggaggaa gtacaaaaaa tgaaaacaaa
     2221 tacaaaaaaa ttaactttaa atgcaatact tttagcgatg ggattattga tacatcaaat
     2281 cacaccagct ataggattac caatgaaacc agatgtacca ctagcaatgt tatttgtaat
     2341 attggtttta aatagagagg attataaaac ttgtttaata gcaggtatag taacaggaat
     2401 atttacagca cttacatcaa gttttccggg aggtcaaatt cctaatgtaa tagataaaac
     2461 tcttacagca aatatagtat ttttattaat gcacattagt tataagatgc ctttcataaa
     2521 aaaattagct aagaaaacac aagatactgt agtagttgca ataataatgc caataggaac
     2581 tcttgtaagt ggaactatct ttttattagc agctcaagct atagttggtc ttccaggggc
     2641 ttcattcaca gctttattct tagcagtagt attaccagct gttttaataa atctagttgc
     2701 aggaatattt ttattcaaga ttgttagtct atcaataaga agagttagtt atcaagctta
     2761 aatacgaaat aatattttac tttataaact attataataa ctgaacaacg taagaataaa
     2821 gtagattata aatattttat tcttatgttg ttcaaagatt tggtattata tatttatttt
     2881 taataaaata tttatatagt accaattaca cttaatctaa cagataaatt atcataccta
     2941 tgcaataata ttcttatatg tattttattt acagttaaaa aatatattta atttactttt
     3001 tcaagaaaaa tttttatatt aatctcttct gatttctcag ttttttgaat acactaaaat
     3061 ttccacttaa attaattata tgtttacatt tataaagttt taaaaatata ataatgaaca
     3121 tattttttgt aaaaaccttg tttaaattta tctaaaaata ggtaattgat agtataaaat
     3181 aaaatttagc aaaaaagttt taacagtagc ataaaagcta ttttagtaag aaacttaaat
     3241 ttctaatatc aagttaaatt ttgagttaat taaataagtg aaacaataat aggattagaa
     3301 tatatgtaaa aatacatctc tatgcttaaa aaagaaaaat aaatttatta aaataacata
     3361 ataaaaaaaa tattaagaat aaaaatataa ttataagtat ttatataaat ctagttgatt
     3421 tttaatataa atgtaaatac aattataact aaatgaataa ttgtatttat atctattggt
     3481 aacatggtct aatataattt gtaattttac ataagtttgt taagtacata actaacctaa
     3541 gagtatgtat ttatatatta aaattttatt ctggggggac aattttatta tgaaattcta
     3601 taaaagaata ttaacattga ttttaagtat ttcttttgta tttgcaaata ttcaactagc
     3661 aaatgcaata tcatctgtag aaaaaataca aggaaaaaat aagtatgaaa tcgcaggtaa
     3721 gatagcagac aaaactgcat ataaaactgc tatattaatt aatactagta actctatcgc
     3781 agatgggtta agtgcaagtg gactagcagg agctttaaat gcccctatac tattaactga
     3841 aaaaaatact ataccaactg aaacgtctgc aagattaaaa aatgtatcaa aagtttatat
     3901 aattggagga acatattcta ttagtacatc tgtcgaaaat tcattaaaat ctaagaaaat
     3961 gaaagttgta agaattaagg gaaacgatag aataaaaaca agttataatg ttgcaaaaga
     4021 aataaattcg ataaaaaaag ttaatactgt tatgttaacc aatgcatata aaggagaagc
     4081 agatgctata agtattgcat ctgtagcagc aagagataaa tcaccaataa ttcttactaa
     4141 tggacaaagt ataccttttt caactagtgg tttaaagtct tatgcgatag gaggaacagc
     4201 ttcaatgagt actactttag taaacaatac taaatctacc agactaggag ggagtactcg
     4261 ttttgaaact aataaagcaa taataaataa gttttataaa gatgcgagag agttttatat
     4321 agctggagct tatgaattaa caaatgcact tgtaggttct tctttatcaa aacatgagcc
     4381 aatggtttta gttaacgatg gtagcaataa aagtgtttta aaaaatgcta agaaaataac
     4441 ttccatagga tatatagatt caaatatagt acaacaatgt ttaaatatta caaatggaat
     4501 tggagatatt aatactggaa ttgtaaaaaa tattaagcct actacaagga ctataaaaga
     4561 tggaatgtat aaggttggaa aagatatttc agcaggtgaa tacttaataa cttcaaattc
     4621 aggaagttat gattcttatt atgaagttac aagtgatagt acaggtaatg ctgatagtat
     4681 actttcaaat gatattttta gtgggactag atatatcact ttaaagaatg gtcaatatat
     4741 taaaattgag gattcaacaa tgatattagc aaaatatgct aaagcccaga aagccaagaa
     4801 tggtaagttt ggaaatggta tgtataaaat tggattagaa attcctgctg gagaatatat
     4861 tataatgtca aattcttctg atgcatatta tgaagttaga aataatagct taggtaatgc
     4921 agaaggaata gttactaatg acactttttc aggaagaaga tatataacag ttgaagaagg
     4981 tcaatattta atattaaatg attgttattt aattgaaaat gaatagatgt aattgtattt
     5041 aatagtaagt aatatatttt atataagaaa ggatgtttta agttttaatt taaaacatct
     5101 ttttttatta ttataataaa ttaaatgatt tttatatttt agaagtatag tatatataaa
     5161 tcattaaatt tactattaaa acacactaga aaaataataa tatctttaaa agatttttct
     5221 tatttgatat aattaaggtt atgtgtaata taagaaatta actaggagga atagaagtga
     5281 gcaaaagaaa acaagtaaca atacctatag agaaaataca agaacaagat aaatatatag
     5341 aacaaataca cagacaaaat gaggaatact tcaacagaac tggaaagaga aaactcgtgt
     5401 ttactcaaac ctttggatgc caaatgaatg aacatgattc agaaaaatta tgttcaatgt
     5461 tagaagagat gggatatcaa atgtcaatga tggtcgaaga aagtgattta ataatatata
     5521 acacatgtgc agttagagaa aatgcagagt taaaagtgta tggtaattta ggacaattaa
     5581 aacacctaaa aggaaaaaat ccaaatatga aaatagctgt atgtggatgt atgatgcaac
     5641 aaccacatgt tgtagaggaa ttaagaaaaa aatataaaca tgtagacctt atatttggaa
     5701 cacataatct atataaattt ccacaattgc ttacagaatc aatgaattct gacaaaatgt
     5761 tagtagatgt atgggatgtg gatggagagg taatagaagg tcttagaagt aatagaaaat
     5821 ttgaattaaa agcatttgta aatataatgt atggatgcaa taatttctgc acgtattgta
     5881 tagtaccata cacaagagga agagaaagaa gtagaactcc tgaagatata attaacgaga
     5941 taaaagagct tgttgcaaat ggaacgaaag aaataacttt acttggacaa aatgtagatt
     6001 cttatggtaa gacacttgaa aatccagttt cattctcaga acttttaaga aaagtgaatg
     6061 atatagaagg aattgaaagg atacgattta tgacatctca tccaaaagat atatctgatg
     6121 aagtaatata tgcaattaga gattgtgata aggtgtgtga gtttttacat ttaccaatac
     6181 aatgtggaag cagtagtctt ttgaaaaaaa tgaatagaca ttatacaaag gaatattatt
     6241 tagaaataat agaaaaagct aaaaaagaag ttccagagat tgctttttct acagatttaa
     6301 tgattggttt cccaggagaa acagaagaag atttattgga tactttagat gtagttgaaa
     6361 aagttagata tgattcagct tttacattta tttattctaa aagacaggga actcctgctg
     6421 ctaaaatgga aaatcaaata ccagaagata taaagcatga gagatttaat agagtattag
     6481 aagctgtaaa taggatttct gcagaaataa atgatggata taaaaataga atagttgaag
     6541 ttctagttga aggaagaagt aaaaataatg aaaataagct ttctggtaga actagacaaa
     6601 ataaacttgt aaatttcgaa ggtggaaatg atgatttaat tggtaagtta gttatggttg
     6661 aaattactga acctagaact ttttcattaa atgggatact agtaaatgat taatattgta
     6721 taaaataata aaattatgta aactaatcga aatagatgta ctatagaac
//
LOCUS       DBGJFK010000119         6566 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.126, whole genome shotgun sequence.
ACCESSION   DBGJFK010000119 DBGJFK010000000
VERSION     DBGJFK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6566
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.126"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            218..394
                     /locus_tag="ACOIAP_003461"
     CDS             218..394
                     /locus_tag="ACOIAP_003461"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640332.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     ICLYQVLLLVSRYN"
     gene            complement(1546..3393)
                     /locus_tag="ACOIAP_003462"
     CDS             complement(1546..3393)
                     /locus_tag="ACOIAP_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGZ2640333.1"
                     /translation="MTKRVLSNFTLTGKNILSKFIFMIRYNFSTLILFELFYKGLALL
                     LILPSIKYIFDNLLKSLNIFYLNMDNIIKILSNPISIVLIILSVIILAFYAFFEFTSV
                     IICFNRSIKCEKIGLFELIKMSFKKSINLLYPKNILLFIFVLLIIPLVNTVLISGFIG
                     KIQIPDYILDYIKSNNILNIVYMISLFIIYILVIRWIFSVHEITLNTENFKIARKESV
                     NLIKGRIIRTVIYSLILSLVMAIIGYVIYHIGIISIGIWTKYYTNIGSLKELFINRCI
                     SFEDYFSLILSIFIFIVDIAFISATYYEYKGVNISRNNIIKEKKSIPKTIFKLSLIIL
                     IFCVESNAYSSHVNGLFNTSFSFNTTTIAHRAGAERAPENTLIALKEALNAKADYAEI
                     DVQETKDGELIILHDSNFKRTTRVDKNVWDVNYDEVRTYDAGSFYYDGKGYYDERFVG
                     EKIPTLDEMIKYSKGRIKLLIEIKLTGHEKGDVTKKVVQLIKENNFENQCIIASMDKT
                     VLQKVKKLDKNLMTCYFMAVAYGDFSKLNYIDVYGIESTFVNTTVVEKIHKMNKKIFV
                     WTVNSYSLIEKMLDLNVDSIITDNPYLVDGAIVWKKNGFINKVSDYLFS"
     gene            complement(3674..4636)
                     /locus_tag="ACOIAP_003463"
     CDS             complement(3674..4636)
                     /locus_tag="ACOIAP_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HGZ2640334.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIVDEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQRITKERNAFRADQFNLEA
                     CNHAHENYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKALKGHKSSIKCYVVEPKTA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQITDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSTERGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            4827..5378
                     /locus_tag="ACOIAP_003464"
     CDS             4827..5378
                     /locus_tag="ACOIAP_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGZ2640335.1"
                     /translation="MSINTIIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SMHTYHNQGEKTLKAVIINYYPV"
     gene            complement(5913..6200)
                     /locus_tag="ACOIAP_003465"
     CDS             complement(5913..6200)
                     /locus_tag="ACOIAP_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640336.1"
                     /translation="MKKFLYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFMTIKIFIFLSLPLCFNILFDYLTS"
BASE COUNT         2414 a          904 c          643 g         2605 t
ORIGIN      
        1 taatttcata atatttttca ttttcaaaca agcatgttga ataatgaagc atcttctagt
       61 attatatatt tgtagaataa aactaaattg gtaaaactag gaatatttag ttttatagag
      121 ttatagtaac tagtactaaa aaattttata agttttgtta ttttgttttt aaaatataat
      181 ttttactttt actaaatttt ttagggggat gaataatatg tttattggag aaatagacaa
      241 atgtacacat atattaactg cttatataag cagttcatat gattattgta attttttaga
      301 tacacagtta gatgatttta tatcagaata cggagaaact gtagttgaaa tatgcttgta
      361 tcaagtttta ttattagtga gtcgatataa ttaaaattaa gtttttccta ggaaaaccct
      421 tttagattta cctaccttaa taaatatata atttttttgt actttataag taactataac
      481 ttctgctaaa gtaaagatgt attgggagta catctttact ttttcattaa aacagtcaaa
      541 aatatacaca taaaaataaa tcattcaata caaattatac attccttata tctaaattaa
      601 tgtatgagca tcattctata cacatattct gtaatttcat caaatatatc tctaaatttt
      661 taccatttta tacattttct ataaagcata caaataacat ttataaaatc cccctagtat
      721 gtttaaacca tctataaaat aacatcaata tttagaatat tcaatatcaa ctgcgtaact
      781 ggtcaataaa aacgtataac tagacaaatt tcaatattta tataaatatt gcaagaaaaa
      841 caatcatttt atttatatat attttttatg ttttgtttat attacaaaac tatattgatt
      901 aatttatttt atttagtaat tataaaaata tacattataa tatattttac aatcgtagac
      961 taacattaat attgttaatt tagccaaaaa ttaaactttt aaaattttta tcctctttta
     1021 tattattaat taagtgtatt atctcaatga tgtttataat caaaacaaca tatttaaata
     1081 ggagaaaaat tatatttatt aaaaccttct atgttataat ttttcattct tatttaatct
     1141 ctatattata acgaaataac tttcctaaat gttagtactt tacttaaaag taggtacttg
     1201 tttaaactta aaatagaaca tatacttata taaatatatg aggagatagc tttcatgaaa
     1261 aaatgtaaga tagaagtaat aaaaactaca tttcataaag acttagtaga taaatatgga
     1321 tatgaaacct tgaaaaatat cctatctata tagaatatac acttgttaga taaaacaacg
     1381 caattacaat tatttatatc aatacaataa tattattatt gtttgtatac tttcacacta
     1441 tcgtagaata aaatacactt atattaataa ttgcttttat ttttaataaa aaaagagata
     1501 ttagtacttt taataatatc tcttttttat tagatatggt aaacattaag aaaataaata
     1561 atctgatact ttattaataa atccattttt cttccaaaca attgcaccat ctacaagata
     1621 tggattatct gtaattatac tatctacatt taggtcaagc attttctcaa ttaaactata
     1681 actattgaca gtccaaacga agattttttt gttcattttg tgaatctttt ctactactgt
     1741 tgtattaaca aaagttgatt caattccata tacatcaata taattcaatt ttgaaaaatc
     1801 accatatgca actgccataa aatagcatgt catcaagttt ttatctagtt tttttacttt
     1861 ttgtaataca gttttatcca tagatgcaat tatacattga ttttcaaaat tgttttcttt
     1921 aattaattgt acaacttttt ttgttacatc tcctttttca tggccagtaa gttttatttc
     1981 tattagtaat tttatcctac ccttagaata ttttatcatt tcatcaaggg ttggtatttt
     2041 ctctccaaca aatctttcat cataatatcc ttttccatca taataaaaac ttcctgcatc
     2101 atatgttctt acttcatcat aatttacatc ccaaacattt ttgtctactc ttgtagtcct
     2161 cttaaaattc gaatcatgaa gtataataag ctctccatct ttagtttctt gaacatctat
     2221 ttctgcataa tcagctttag catttaaagc ttcttttagt gctattaaag tattctctgg
     2281 agccctttca gctcctgctc tatgagcaat agttgttgta ttaaaggaaa atgatgtatt
     2341 aaacagacca ttcacatgtg aagaatatgc atttgactct acacaaaaaa ttaatattat
     2401 tagtgataat ttaaaaatag tttttggtat ggattttttc tcttttataa tattattcct
     2461 agaaatattt actcctttat attcataata agttgctgag ataaatgcaa tatccactat
     2521 aaaaataaat attgataaaa tcaaactaaa atagtcttca aatgaaatac atctatttat
     2581 aaacaattct ttcaaagatc ctatattagt atagtattta gtccatatgc ctatagatat
     2641 aattccaata tgataaatca catacccaat aatagccatt actaaagata atattaatga
     2701 ataaataact gttcttataa tccttccttt tataagatta acactttctt ttcttgctat
     2761 tttaaaattt tctgtattca aagttatttc atgaacacta aaaatccatc tgataactaa
     2821 aatatatata ataaaaagag aaatcatata aactatattt aaaatattat tagactttat
     2881 atagtctagt atgtaatctg gtatttgtat ttttcctata aaacctgaaa ttaaaactgt
     2941 atttactaat ggaattatta ataacacaaa tataaataat agtatatttt taggatataa
     3001 taaatttata gatttcttaa atgacatttt aataagttca aataaaccta ttttttcaca
     3061 ttttattgac ctattaaagc aaataattac agaagtaaat tcaaaaaagg cataaaaagc
     3121 taatattata actgataata taatcagaac tatagatatt ggattactca aaatttttat
     3181 aatattgtcc atatttagat aaaatatatt taaacttttt agtaaattat caaatatata
     3241 tttaatagat ggtagtataa gaagtaaggc caatccttta taaaataatt caaataaaat
     3301 taatgtacta aaattatatc ttatcataaa aatgaattta cttaagatat tttttcctgt
     3361 gagtgtgaaa ttacttaata ctctctttgt catatttacc tccttgtatc tgtttattgt
     3421 atttttatac aatattttaa atgtatatag aatattagta tatattattc caaattataa
     3481 tatgtaaata caaaaacata tattcatttt tattttatga ctaagcataa ttatctatat
     3541 aaatttatgc ttatagtcat gatactacat gtttattaaa aaaaaaagta tctcattaat
     3601 ttttaaaaat cattttgaga tactttttac aatttaaatc catatattta acttaagaaa
     3661 cactgtatca ttattataat tcttcatata aatcagtact caagtatttc agaccactat
     3721 cattaagagt caaaactata tttttacctc tttcagtact ctttaataac ttaattgctg
     3781 cgcatacatt tgctccagaa gaaaaacctg caaatacacc ttctaattta gctaattttc
     3841 ttgctacatc agttgcctcc tcatctgtga tttggatata accatcaata agtttcttgt
     3901 ctactagtgg caagtccata gaatatcctc caccttggat tttatgacct tggtcagtta
     3961 tttctttacc tgagtaaatt gctgctgttt taggttcaac tacatagcat tttatagaag
     4021 atttatgtcc tttaagcgct tttgagcaac cagcaaaagt actaccactt ccaagaaaat
     4081 ctacaaatac atcaatattt ccatccaatt gttcccacat ttcttctgct gtataatttt
     4141 catgtgcatg attacaagct tctagattga attggtctgc tctaaatgca tttctttctt
     4201 ttgttattct ttgagcttca atttctacaa gcgctaaatc ttcaccagat acttgtccat
     4261 gaactgagtt aggcatttgg tctacaagaa ctacttctgc acctaaagct ttcatcattc
     4321 ttgctctttc catagaattt ccttttgaca tacatgctat aaatttataa cctttacatg
     4381 cacaagctat tgctaaccct gttccagtat taccacttgt taattccaca actgcttgac
     4441 ctggaactaa taagcctgcg ttttctgctt cggtaatcat ttgtaatgct acacggtcct
     4501 ttttgctaaa tcccggattt aagtattcca tctttgcata aatattacct tgaactccaa
     4561 attcatctac tattttggat aaatgtaaca tatgagtatt gcctatagcc tctgtaacat
     4621 tattaagtac acgcattaca attccccctt aatctctcaa ctatcatccg ttgaaaaaca
     4681 attctttatg cagtataatt tatattacgg atgtacagtg tatttaacgt tcattatatt
     4741 atacatttgt aaattataaa taacgttaaa taaattatat attcgtaaat tatatttgtc
     4801 aataatttac attttaagga gctaatatga gtattaatac tattattgct aaaaacctaa
     4861 atagattacg taatgaacgt aacttaagtc taggtcaact tgccgaattg tctggcgtaa
     4921 gtaaagtaat gctttcgcag attgaaaagg gagactcaaa ccccacagta aacacaattt
     4981 ggaaaattgc aagtggacta aatgttccat atactgcaat actggaacaa ccccaaaatg
     5041 aaacttttat tgtatcaaaa actgatatag atgtacaagt ttcagagaat aaagattatc
     5101 gtctttattg ttattatcct aatacaccaa ctagaaactt cgaattattt caaatggaat
     5161 tagaagaagg tcatagctat acatctgttg gtcattctga aaaatcacag gaatatatta
     5221 tgattataga aggtcaatta aaattagaag taaatgactc tatttatcaa cttagagaaa
     5281 atgactctat ttgtttttca gccgaatcaa tgcatacata tcataatcaa ggagaaaaaa
     5341 cattaaaggc agtaataata aattattatc cagtttagcc atgtcattta atgatagaat
     5401 aattattttc tatacaaaaa gataaatcct ttgattaaga tttatctttt tcattttatt
     5461 tttctttata aattcattat atatctttac acttttatca attatgttat aataagctta
     5521 tataaaagtt ttatattttt gacaaatgga gtacaaaata ctcctttttc ttttttacta
     5581 ttgtgataat tatttagtta gtattaaaat attatcactt aaaacaaata caaaacgtct
     5641 cttatatgta catttttcat tgttgtaata atgatttgtg tatgtatttc tcacaatcgg
     5701 agtgcttatg cactcttttt aaataccttt attaccacaa tctaaaagct attttattat
     5761 ccattttaat ttatttttaa gtaatcaaat aaattatttt atattttttc ttcatttata
     5821 tgaaactttt ttatcactat atgcacttta tatttaatat aaataacaca taagcttgct
     5881 tttatcataa cactccaata tttaaatata atttaagaag ttaaatagtc gaatagtata
     5941 ttaaagcata atggtaatga caaaaatata aaaatcttta tagtcataaa ctttatctta
     6001 tcatttttat cttctccatt aaaataatta tcttgataaa atgtagctct attttgataa
     6061 cctgttttta aaactccatt ttgaattaat agcagtataa aaaagattgc taataaaata
     6121 aagttataat ttttttcttt taatctaaaa ttcgctataa taacaatgaa actatataaa
     6181 gcatataaaa attttttcat aaaaaacacc taaattctat atttgtattt tatattgagc
     6241 caaatctaat ttctgtatac ttattaagtg tagttctaat ttatattgta gttggattaa
     6301 atatttctta atttttattt tcaattattt ttataatgtt tatacctcta tcaatattaa
     6361 attttgatat ttgtgttgtt taacattgta ttactattaa aatctttttc aacaaataca
     6421 aatggtatat atactttaat attatcaata ctgatagtac aagtagtaca aaccctttaa
     6481 gtttataaga gcatctcctt atatctaaat tatagtatga atattcacaa atttcaatct
     6541 atttataagg taattatttt tatatc
//
LOCUS       DBGJFK010000120         6291 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.127, whole genome shotgun sequence.
ACCESSION   DBGJFK010000120 DBGJFK010000000
VERSION     DBGJFK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6291
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.127"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            276..434
                     /locus_tag="ACOIAP_003466"
     CDS             276..434
                     /locus_tag="ACOIAP_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640337.1"
                     /translation="MKIFSFMLYVVGICFCIAGFIGHYPAFAGATLSFFATTMIAVNQ
                     GKTKKKMK"
     gene            complement(723..1427)
                     /locus_tag="ACOIAP_003467"
     CDS             complement(723..1427)
                     /locus_tag="ACOIAP_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640338.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQGNINNDAPKSFEVKNLKIDYENHTVLINDEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(1418..3025)
                     /locus_tag="ACOIAP_003468"
     CDS             complement(1418..3025)
                     /locus_tag="ACOIAP_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HGZ2640339.1"
                     /translation="MKKERLQHEDLKEYDYDEDVYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGIACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESS
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPVYDEEGKDKWK"
     gene            complement(3281..4459)
                     /locus_tag="ACOIAP_003469"
     CDS             complement(3281..4459)
                     /locus_tag="ACOIAP_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640340.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(4683..5177)
                     /locus_tag="ACOIAP_003470"
     CDS             complement(4683..5177)
                     /locus_tag="ACOIAP_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGZ2640341.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTRIKENEKYKNSINKI
                     KQQK"
     gene            complement(5178..5939)
                     /locus_tag="ACOIAP_003471"
     CDS             complement(5178..5939)
                     /locus_tag="ACOIAP_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGZ2640342.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFIGVSIAVGMFLVLGLYFKLGGI"
BASE COUNT         2117 a         1169 c          676 g         2329 t
ORIGIN      
        1 atcaaaaaag agttaaattg atttatccat ataaatatta tatctaacaa ttctacttac
       61 ttttcttaca cttattagca tatagttttc gagagcttat tacaaactaa cacttagcac
      121 accttaaaaa atatggtctg ataagtaatc atacaaagaa tacacgataa accataaaat
      181 atgacatact ttttcacgtc atcaaaactg atgatttcac tattaatata tgataaaata
      241 tgcttaataa attaaatttt aaagggagaa tagttatgaa aatatttagt ttcatgttgt
      301 atgtggtggg aatatgtttt tgtattgctg gatttatagg acattaccca gcatttgctg
      361 gtgcaacatt gagttttttt gcaactacaa tgatagccgt aaaccaaggc aaaactaaga
      421 aaaaaatgaa ataagtaaat gccaacttta caagctagta ttacacaagt agttagtcta
      481 aaattggctt actttttcta ttatagaaat acatcatcaa ctttacattc tcttggaaaa
      541 ataaaaatag ctatgtaaat tcaatattag atagactaac tctctatcca tttcattata
      601 aaatatacat agctatttgt attcgattta aaatacttat attttcttat ataacaaata
      661 atttctatct gattactact catattcatt tggtgaccac tcatcaacta cccatttagt
      721 atctattcat ctgccatacg gtaacctacc ccaacctcag tcaaaatata ttctggctga
      781 gcaggattct tttcaatttt tcttcttata cttgccataa aaactctaag tgactgattt
      841 tcactttcat agtaatttcc ccaaacttta tctattatga acttatgagt taaaactctt
      901 cctgaatact tagacatcaa ctcaataatc ttatattcaa ttggagttaa atgtatttct
      961 tcatcattaa ttaacacagt atgattttca taatctatct ttaggttttt gacttcaaaa
     1021 gattttggag catcattatt tatattgcct tgttgagctt tatttctaag agctacacgt
     1081 actctagcca aaagctctgt tacactaaaa ggtttagtta aataatcatc tgcccctcca
     1141 tctaaagcct ccaccttatc cctctcatgc tcccttgctg aaacaacaat tattttatta
     1201 gtcttggcac atgccctaac tcgtcctatt acctcaattc catcaatatc tggtagtcct
     1261 aaatccaaaa ttatcaaatc tgggtcaaga gaatgtataa gtgatatagc tgttcctcca
     1321 ttatctgtct ctacacacct ataattttga gtttcaagag atacttttat aaatttacaa
     1381 attggcttat catcttctac aattaaaact aatggcttta tttccacttg tcttttccct
     1441 cctcatcata cacaggtatg ctaaatctaa atgtagctcc tccagaagga ttattaaagg
     1501 cgacaatttc tccaccatga gcttctacta tagatttaca tatctccaat ccaagaccaa
     1561 tacctcttct ttcaagattt ctagacttat tcttagtata aaacctatta aaaatattac
     1621 caatatcttc atttggtatt ccttttccat tatctgcaac ttcaaatagc acttgacttg
     1681 actctttttt tacagttagt tctatcttag aatttttagg tgtatgcctt atagcattat
     1741 caattaggtt tactaaaact tgttctatca ataatacatc cacatgcacg attattatct
     1801 catctggaat attggttttt atatctctac tattggcaaa ctttttgact cttaatatag
     1861 actctgctat tatttcatca acaacctctg gtcgtttttc aatatccaat tttccttcat
     1921 ctattctggt catactaagt atattctcaa cagaatgagt tagccaactc gtatcttcat
     1981 atatattttt taataattcc actctagttt ctttatctat cacatcatca ttttcaagta
     2041 tagttgaaga tgaacccaat atacttgtaa gtggagttct taaatcatga gaaattgacc
     2101 taagcaagtt tcctcttaat ctctctctct ctgcctcaag atttgctttt ttattttttt
     2161 caaataaatt ttctctatca attgccaacg caacctgtgt tgaaactgct tctaatagta
     2221 tcttttcatt ttctgtaata atatctatct taaaacacgc aatacctata acaccaagaa
     2281 catttgattc ttgacctttt ataggaaaat aatatgcact gctgttttta caatattttg
     2341 tcccaattcc aactgggtta cccgtcctaa aagcttcttt tatagcttcc ttttctaata
     2401 ctgaatggaa tatattctca cttccatcat tattacaaat ataaatactt ggcttaccta
     2461 gattattatt ttcatctgca atagtcacta ttacagttct atttaatata tttactaaat
     2521 tagacccaca aaattcaata atttgatttt tattttttgc tttaagcaac gttttgttat
     2581 tctcataaag taatcttatc attttttctc tcttatgaga aagtctcact tctcttttta
     2641 tcctagaagt taaagtactt gttataattg ctgccatcag cataatacaa aaggtcatag
     2701 ggtaatcttt tctataagct aaaaaagtat ataatggatg tgtaaagaaa aaattaaatg
     2761 atagcactcc tattactgaa gaaagtattc caaaaaaata tccataggtt atacttgtag
     2821 caaatagtac acctaatata tatactagta taatattaga ttcattaaaa cctacttttt
     2881 caaaaactac tgatattcca gtagcaattg tcataactaa tatagttttt atgaagtcct
     2941 taataattat ctttttactg agataaacat cttcatcata atcatactct tttaagtctt
     3001 catgttgtag tcgttccttt ttcatttact acaattcctc cttattgtta ctgtttaaat
     3061 tggctctatt ttatataata caattttatc ataataaatt caatcaatac atttaattaa
     3121 tgtatttaaa ttactaaaag gtgctgtctt aaaatgaaaa taaatctcta tttcaaaaca
     3181 gcacctctat atatttaaat tgataattta atttttatat acttaaatta ttagttttat
     3241 ttaatttcat aaattataat acttgattta tcgaatattc ttatccaacg agcataaata
     3301 taaagtgggc acatatacct gcacataaac cacctatagt atgcgaaagt atcgctttac
     3361 cagctaatgg tcttgcatct agagcatcca tcatacctat gtgtgtactt aaatatccac
     3421 tccaacacat acccattgct gtgaatactg ctatatcatt aggagttata gcgcctgatt
     3481 ttataaactc tggtactaaa gatattgctg ctccaacagc tcctaatgca gttacaggga
     3541 atgctattgc ttctggtgat gtaaatccaa ataatggctc tattataaag ctaatcttat
     3601 caccaatagc aggtaataat tttatacctt catatgcagc tcctgtgtaa acagcctgac
     3661 ctgtagcagg gtctgtagat ggtccaaaag ttaataacat aactaatgta caaactacta
     3721 aaacgcctgg tattatagcc atacccattt caacacctaa cttaccacct tcaagtatag
     3781 catccaatgt tctttggaat acattaccat ctcttatttc tctaaactct tcaagttttg
     3841 cacctttatc atttatttgc ttttcagtat catttttagg gtcataatta taatactttt
     3901 tagtaaaagt caacataatt ctaacactaa taatactacc tattattgcg ccaacattac
     3961 ctattatagc tggtagtaca tattctttac cttgagctat cataaaagtt gttacaataa
     4021 gtcccatacc aaaggctgtt cctaaattac ataaagcagg tacttgatac ttcttaaaat
     4081 attgtgtaaa tgttttgtct ttagcaaatg gtataatagc tggattatca gataaatatg
     4141 ttgcaactac tcctgctata ctagcaccag gtaagcccca tataggtctc ataagcccct
     4201 taaatatctt attaactaaa gatattactc caaactctga aagcaacgca ctaagtgcac
     4261 ctgcaagaac tgccatagcc attattaaaa atactgtgtc taataaaagc gcatgtgctg
     4321 tactcattat tactttaaac atcattcctg cacccatgat gcttcctaca tatccaaatc
     4381 ctaccgccaa tagtacaata aatacgaagg tttccatact tactgccttg actcttctct
     4441 tatccgacag cttttccatt ttgaaatctt ccccctttta attttaaatt aaggttccta
     4501 acattggtac aaactttttg gtacaaactg agttctaaaa cttacactcg taatgcaagt
     4561 tgtcagtttt ttgaaataaa aaaattacgt tcatagaata agaatatcat ctttattttg
     4621 gatactctta ttctatttta tgttattata ttatcatcct tttgtttaaa agtcaatttt
     4681 ttctattttt gttgtttaat tttatttata ctatttttat atttttcatt ttcttttatc
     4741 cttgtaagca ctccatataa gttgactttt ctaaatacag tagttataaa taccaaacct
     4801 aatgcaattg agcttgcaca tgataatgta ctcacaccat attctacagc ttttatataa
     4861 ttattggtta aaacagaata catagtatta tatattccat aaccaggtac taatattatt
     4921 aaacaacaaa cacttaatgt agttgctgga gtcatataaa ttcttgcaca taactcacaa
     4981 tatatcgcaa aacaaactgt agctataaaa aaacataagt tttctgttac tcccatattt
     5041 aaaagaaatt tatatgaaaa ccaagctata cttccaccta ttcctgctaa tattaagttt
     5101 tttcctttca tattaaatag cactccaaag cttaaggcag taaaaaaagc tgctattact
     5161 tctataaaca aatgcactta tatcccccct aacttgaagt acaatccaag taccaagaac
     5221 attcctactg ctatagatac acctataaaa aatacttctg ctaattttgc aagaccagaa
     5281 atcaactgtc catctaacaa atctcttagt gcattagtca aagcaagccc aggaactaaa
     5341 agcattattg ctcctgctat tagatggtct agcgtcttta taaatccaag ctttaaaatc
     5401 aaaattgaac aagaagctat aataactgct ccaattgcat ttacaaaaaa gtcattaagg
     5461 gaagatttac ttaagtacat aataacaaac ttagtcaaaa tcccaacagt aaatgcagct
     5521 ataaattctt ccacatttcc tccaaataat atcgaaaaag ttgctgctgc aatacctgca
     5581 aaaaatattg ttattaaatc tgagtaatag ttatcttcac ttatttcatc caaaattttc
     5641 tcacataatt caatatctaa attatttata cttattgctc ttgataatga gttaacttca
     5701 tgaaccaagt ttaggtctac tcttcttgag cttattcttt taattgctga atgtaatttt
     5761 ccatctacaa atacagatgc catcacagct gttggagtag caaatacgtc cacatgatct
     5821 attccaaaag attgacatat tctagctatc gtttcttcaa ctctataggt ttctcctccg
     5881 ctttgcaaca tagctttacc tgcatttgag gaaaagttta aaattctatc tatatccaca
     5941 aaacatatct cccattcttt tatagtatta ttcatatttt aatacaagtt attatttatt
     6001 taaactattt caaataaata atatccaata tttacatttt atgaaaaaac ttgtttttta
     6061 tgcttgtcaa aaccaaattt taaggttgtt tacaccataa aatggctgaa ttaatatttg
     6121 acaaacactt tcaaccattt atataacctt ctaaattgta taacttttta ctacaaataa
     6181 aattatatct ctttttattc tttctcttgg ctctttaagt ttacagcaac ttcatattta
     6241 tatatgtaca atataaaata ttatttttat gatacaaaat ataatttgta a
//
LOCUS       DBGJFK010000121         6149 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.129, whole genome shotgun sequence.
ACCESSION   DBGJFK010000121 DBGJFK010000000
VERSION     DBGJFK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6149
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.129"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(172..2244)
                     /locus_tag="ACOIAP_003472"
     CDS             complement(172..2244)
                     /locus_tag="ACOIAP_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HGZ2640343.1"
                     /translation="MEKYRALKLVSLIIISISFPLTILLATIGLAEPKYNIQKTSTKS
                     GIFNISNDFYDSNIFDEGTVASLLSNFKISVDSQLTSEEKSKFQTKSKSIDLSSNDSE
                     YDKIMINKQASEEYLGYLKNIKVYVINTYTGVFYTNTSYDNLNDFKQETKNYCNIEII
                     NNVGKSSYIKTINGEKFELNNLSMELNGVDEAFEAYVSFPEEPTMEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLFIILYSRIKCEVLKRHNVFLLIYSKIPMEFNIILVS
                     ISIAILTIYALAVSYHIDVIVLVSLSLLIVSNNIFFINVQLSYLENKMYIFKTSIIVR
                     VILWLIRTVREVSNAIKKVSLARKVIVIVIISLALIMVISARSISMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVDLQGGKFYIEIDGDLFKANLEFQKYEEEV
                     TNMEKDGI"
     gene            complement(2440..3132)
                     /locus_tag="ACOIAP_003473"
     CDS             complement(2440..3132)
                     /locus_tag="ACOIAP_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640344.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIMGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            complement(3718..3852)
                     /locus_tag="ACOIAP_003474"
     CDS             complement(3718..3852)
                     /locus_tag="ACOIAP_003474"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640345.1"
                     /translation="MKNIHKNSISSLMSALHGEYDEVDEDKLIEIEEHFKSLKEENDS
                     "
     gene            3997..4230
                     /locus_tag="ACOIAP_003475"
     CDS             3997..4230
                     /locus_tag="ACOIAP_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2640346.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            4214..4627
                     /locus_tag="ACOIAP_003476"
     CDS             4214..4627
                     /locus_tag="ACOIAP_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640347.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLIIYCILKEKRFLISSFLLIAI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLIVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            4646..4846
                     /locus_tag="ACOIAP_003477"
     CDS             4646..4846
                     /locus_tag="ACOIAP_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640348.1"
                     /translation="MCFKTYILKRVLNNKHLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEKNNVVWRNEKSTPQQENA"
     gene            5224..5541
                     /locus_tag="ACOIAP_003478"
     CDS             5224..5541
                     /locus_tag="ACOIAP_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640349.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLELLYRYVTGLEYIAIGLFTRRLDITIITIILVSTITTALYYLIRKKY
                     ITI"
     gene            complement(5602..>6149)
                     /locus_tag="ACOIAP_003479"
     CDS             complement(5602..>6149)
                     /locus_tag="ACOIAP_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HGZ2640350.1"
                     /translation="LNKENKLSKLVLVNGEKGLADAVSMGAISAKEKMPILLTNQNDD
                     MKEIEELIDNKDISKSYIVGGESLFNKDIEDKLPSVIKISGEDRTETNSKVIDYFYNN
                     SVLDNLYVAKNGENKEDDLVDALSVGVLAGKTESPVIIVGDGIKDVQKSLIKKKEFRY
                     ITQIGGNGNEKAFSEIENLVK"
BASE COUNT         2108 a          920 c          619 g         2502 t
ORIGIN      
        1 tataagttat tttataaaca tatgtacaat tttaatctaa attgttatat tattgatttt
       61 aaataaaaaa acagagtggc ttaaatctac tctgttttta ctcttcatcc tctactataa
      121 atattctaat atattataat aagagcttcc tacaatcaaa agtatgtata cttaaatacc
      181 atctttttcc atattagtta cttcttcttc atatttttga aactctaaat ttgctttaaa
      241 taaatctccg tctatttcta tatagaattt tccaccttgt aaatctacta agtctcttgc
      301 aatagcaagt cctaatccac taccttcagt atttcttgat tcatcagccc ttttaaatct
      361 ttccataatc tcactagggt caaaatttaa ttcataagaa gatatatttt tcatagttac
      421 ctttacattt tcaccatagt catatacatc aatatagact ctagtttctt ctaaagaata
      481 ttttgctata ttagataaaa gattttcaaa tactctgtac attcttcttc catctgccca
      541 tatatacacc ttatcgtttg gaacatttaa ttttaaatat aaattatttt tagataattt
      601 ttcttcaagt tcacctatac tttgtcttaa tagttgcact aaatcaatct tgctaatttg
      661 taattctata ttgccactac ttactctact cgcttcaaat aaatcttcta tcaataattt
      721 tagtcttttt gactttgact caagcacatt tatataatca tttatatact ctggttgtat
      781 tgattcttct tttttaatta aatctacata atttattata gaagtaagtg gagttttcaa
      841 atcatgagat acatttgtta taaggtcaga cttcattctt tcacttttta cttgctcttc
      901 tatagctcta tcaagacctt ctccaatatt atttatattt tcagctaaag acgtaaaatt
      961 atcattccca gtaattttta tcttataatc taattctccc ttttttattc tttctgtacc
     1021 ttctattacg taactaagat atgaaagtct tttagttata tatattgtaa atcctaaaaa
     1081 aatacatata gaaaacagta atcccatact tatacttcga gcactaatta ccatgattaa
     1141 agctaaagat attatcacta taacaataac ttttcttgct aaagatactt tctttatagc
     1201 gttactgacc tcccttacag ttcttattaa ccataaaatc actcttacta taatacttgt
     1261 cttaaatata tacattttat tttctaaata actcagttga acatttataa aaaatatatt
     1321 atttgatact atcagtaaag ataaagaaac taacacaatt acatcaatat gataagatac
     1381 agcaagagca tatatagtta aaattgcaat tgaaatagat actagtatta tattaaattc
     1441 cataggtatc ttactgtata ttagtaaaaa tacgttatgt ctttttaaaa cttcgcattt
     1501 tattctacta tataaaatta taaataataa acatataatt gctaaactta aactagctac
     1561 aaaaaataat cttacttttt ctgtagcttg tttaaatatt tgaaaattag tgtatactat
     1621 tccatcttcc atagttggtt cttctggaaa agatacatat gcctcaaaag cttcatctac
     1681 tccatttagt tccatactca gattattcag ttcaaatttt tctccattta ttgttttaat
     1741 atacgagctc tttcctacat tatttattat ctctatattg caatagttct tagtttcttg
     1801 tttaaaatca tttaaattat catatgatgt atttgtataa aatactcctg tatatgtatt
     1861 aataacatac acttttatat tttttagata acctaaatat tcttcagaag cttgtttatt
     1921 tatcattatt ttatcatact cagaatcatt actacttaaa tctatacttt tactttttgt
     1981 ttggaattta cttttttctt cactagttaa ctgactatcc acagatatct taaaattgga
     2041 taataagctt gccactgttc cttcatcaaa tatattacta tcataaaaat cattagatat
     2101 attaaaaatc ccactctttg tagaagtttt ttgtatattg tatttaggct cagcaagtcc
     2161 tattgttgcc aacaatatag tcaatggaaa tgagatagat attatgatta atgaaactaa
     2221 ctttaatgct ctatattttt ccaagttgtt cacctcatct acattgtcag tattttatat
     2281 aaaataaagt ttaagaaaag cataatcccc atagagtaaa ttaaactctc agagaaaaaa
     2341 ttaaaacata ttaaaattcc taacatttgt gtaaatgtaa aaatgactaa aatcaaaatg
     2401 caattaaata ttaaactctt ttcttttata atttttccac taaaattttt caatcttata
     2461 accaactccc cacaccacct ttaaaaatct tggttctttt ggatttattt caatcttttc
     2521 tcttattcgt ctgatatgta ctgctactgt attttctgag ttaaaacttt cctcattcca
     2581 tactttttcg tatatctcat ctattgagaa aactcgtcct ttattttcta aaagaagttc
     2641 aattatttta tactcaattg gagtcatttt tatgttttca ccatcaattt taacttcttt
     2701 tgttagtgta tttaactcca aagctccact ttttaaaatt tctttacatg tatcttcata
     2761 attacctaaa gttacatatc gtcttaagtt tgatttaact ctagctataa gctctaatag
     2821 attaaatggc tttgttatat aatcatcagc tccaatattt aatcccatta ttttatctgt
     2881 atcttcactt tttgctgaaa ttaaaattat tggaatgttt ctttcttctc gtatttttac
     2941 agttgctttt attccatcta atttaggcat cattatatcc atcagtatta gatgaatgtc
     3001 attctctgtt attatttcca aagctttcat tccatcatat gctttatata tcttaaatcc
     3061 ttctgattta agatatattt ctattgaatc aacaatttct ttatcatcgt ctactactaa
     3121 tatattgtac atgttttcac ttcctctatt gtataataat acttatctat attatacaat
     3181 atctttcact tcctttctca acaatgacta aattgttata ttactttgac ttacattttt
     3241 gtaactttct cttataagtc tataataaaa tataaatctt aagaaaatat tatcctaatt
     3301 cttaaatatt tcttaagatt taagagaaat tgaggtttat ttgaataaat tgatttgaat
     3361 tatgttgttt tcagattact tttatttaag tattttgatt ggattcagct gaattaatgt
     3421 atattaattc ttattgaaca gtttttattt tttgggtgga agagtggtgg aagaattaca
     3481 tttcactaat tttcttccac ccaaatatac ttagaaacat ttatttcgct gcaataatag
     3541 ctgcttattt aaattctatt tttatacata ctatctacta tatactatgc atattctatt
     3601 aaaatttata taaatataaa acaaatctat ttcattttct taacatgttc agaataataa
     3661 acaaaatgaa ggtagaaaaa gttataattt cataccttca ttttatttat tatgtatcta
     3721 gctgtcattt tcttctttca aactcttaaa atgttcttcg atttcaatta atttatcttc
     3781 atccacttcg tcgtattcac catgtaacgc tgacattaaa cttgaaattg aatttttatg
     3841 tatgttcttc aaaaattctt tcgtttcaaa ccttagatat ttttttcttt taggttttta
     3901 taatacttat ctaataagat tgacatttta ctcattttag gatattatga agctaacttc
     3961 acatgaagtt aacttcatac agaaagaggt tatggaatga aaacaaaagt acgagaattt
     4021 cgaacaaata tgggtctaac acagcaacaa ctcgctgatt tagtccatgt atcaaacaga
     4081 acaattattt ctattgaaaa agagcaatat agcccttctc ttatgcttgc ctatcgtatg
     4141 gcacaagtgt ttggtacaac tattgaagaa ctatgttgtt taaaggaaaa taaagaaatg
     4201 gaggataaaa aacatgaaag taaagagtaa acgaagtttt atagtgggta ttatagtttg
     4261 tatgttatgt tgtgctagtt taattattta ttgcatttta aaagagaaaa gattcctaat
     4321 ttcatcattt cttttaattg caatagcaat ctttaatttt tgtaatgctt tttcaagaaa
     4381 aggtattgtt gaagaattac acgatagtac agatgaaaga gacttgtact taacaatgaa
     4441 aacaagtcat atcttagtta aaattatgaa ttatacatta tttactttta catttctttt
     4501 catcatagct tatagtgcat ggaaaaatca atcacttata gttatagcta taacactatg
     4561 tgtcattgag atttttttat ttgttgcata tttacttatc aatatatttt tagagaaaaa
     4621 agagtaaata caagaggtga tacaaatgtg ttttaaaact tatatactta aaagagttct
     4681 aaacaacaaa catctagaga taactcgaag tttcgactta gataatctca tttgtactgc
     4741 aacagagatt ttgaaagata atgagattga tttaataatt acagatgaaa aaaataatgt
     4801 tgtttggaga aatgaaaaaa gcactcccca gcaagagaat gcttaattac aactatagaa
     4861 gtgtactgcg aatacacttc tattttttat tatatcatat aaattatgtt gttaaaaaga
     4921 gctatttaaa tcaattttaa agggttttga gtaacagtct tgatagttta tacattaata
     4981 aatttaaaaa aagaagcact cctatagaaa gagtactttt agtgtatatt caagaatttc
     5041 tctaacatga ttataacgtg tcttatgttt tagtatgata attttcgtta gttttattat
     5101 tgcaacttat actatatagt tttatgcgtc ctgttaatat ttgtaatatt ttagatactc
     5161 tttatacttg tgttactgat atactttgat taagaaaatc aaatctaaca ggaggtttct
     5221 actatggatt ttggaaatat caatcttata cttattggaa taatagttat aataggaact
     5281 acaataatat atttaattaa acctaaaact gctttttgta gtaaaaaata tttcaataaa
     5341 ttagaatcaa tatatggaaa tatagataag aaaaaaactg ttaaactaga attactttat
     5401 cgctatgtaa caggtcttga gtatatagca ataggcttat ttacaagaag attagatatt
     5461 acaataataa caataatatt agtatctact ataacaacag cattatatta tctaattaga
     5521 aagaaatata taactatata aaatctaata aaattaatac taagagaagg tagcaactag
     5581 ttacggttgc taccttctaa tctattttac taaattttct atttcactaa aagctttttc
     5641 atttccattt ccaccaattt gagttatata tctaaattct ttcttcttta ttaaactttt
     5701 ctgaacatct tttattccat ctccaactat tattactggt gactctgtct tacctgcaag
     5761 aacacctact gataatgcat ctactaaatc atcttcctta ttttctccat ttttcgcaac
     5821 atataaatta tctaaaacgc tattattata aaaataatct attacttttg aattagtttc
     5881 tgttctatct tctcctgata ttttaattac agatggaagt ttatcttcta tatctttatt
     5941 gaataaactc tctccaccaa ctatatatga ttttgatata tctttattat caattagttc
     6001 ttctatttcc ttcatatcat cattttgatt agtaagaaga attggcattt tttcttttgc
     6061 tgatatagct cccatactta ctgcatcagc aagacctttt tctccattta ctaaaactaa
     6121 tttagataat ttattctcct tatttaact
//
LOCUS       DBGJFK010000122         5059 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.130, whole genome shotgun sequence.
ACCESSION   DBGJFK010000122 DBGJFK010000000
VERSION     DBGJFK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5059
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.130"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            318..3152
                     /locus_tag="ACOIAP_003480"
     CDS             318..3152
                     /locus_tag="ACOIAP_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGZ2640351.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKIGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKIPGKPILFLHASIIENLIGRTLNSNEFSINNCNELLKSSKN
                     DTEDIFSTLLGYDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIRVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSEIDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     STYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     AIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEISYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNNKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     LTIIELIDEELKSKFKLGYILHCSFMIERCFKNTTFPYNNITEIISKNHELYSLIREA
                     FKPTEAYFNIFIPDEEIAYIIDMINEYLNK"
     gene            3195..4439
                     /locus_tag="ACOIAP_003481"
     CDS             3195..4439
                     /locus_tag="ACOIAP_003481"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGZ2640352.1"
                     /translation="MEDEILKGKIKQLTILTLIFIFITPGFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAIDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAALAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENISTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMIPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSASLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKIKVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVNVKSESNIGCIPLKDK
                     IKIRVAKINRKLDVKNSVCFKV"
     gene            complement(4896..5048)
                     /locus_tag="ACOIAP_003482"
     CDS             complement(4896..5048)
                     /locus_tag="ACOIAP_003482"
                     /inference="COORDINATES: protein motif:HMM:NF037487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640353.1"
                     /translation="MLVKAGAVSETTATDSVANATFEVKKHVAAPISTIGKISSGLSS
                     LFNILR"
BASE COUNT         1964 a          659 c          751 g         1685 t
ORIGIN      
        1 tttatcattt ttttcatata tatcgactat acatcaatta tatcaaccat atattaataa
       61 atgatattac ataaattgaa atatattgaa aaacttaaat ttagttatgt aacaacataa
      121 tactctaatt taatctataa aaatctatac ctaatataat gcaactctta ttttaacacc
      181 atctattaca caaaacaaca tattaaaaag taaaatacaa aatatccact ataaacctta
      241 ttttaatact aaatatatat tataatgtat ttaatatagc ttaaatatat tttaaacata
      301 aagaaaggag acgatatatg ctaagaaaag ataaagttct attatcacta cataaattat
      361 gtgaaaatat gactttaaaa gaccttcagt cagataaaat aggattcact acaatagaaa
      421 ttgctaacca ttcatctctt gatagaagta ataccagtaa agaattaaat aacctgtata
      481 atgaaaaaaa agttctgaaa atacctggta agccaatttt atttctacat gctagtatta
      541 tagaaaattt aattggacgt actttgaaca gtaatgaatt ttctataaat aattgtaatg
      601 aactacttaa atcaagtaaa aatgacacag aagatatttt ttcaacatta cttggatatg
      661 attctagtct taaactacct atagaaaaag ctaaatctgc tatactctat cctccaaaag
      721 gtcttaatac attactcata gggcctactg gtgttggaaa aagtacattt gctgaaacaa
      781 tgtacaaata tgctgtagaa agtaaaatct tttcttctga aagcaaattc gtagtattta
      841 actgtgctga atatgcagaa aatgctaact tattattaag taacttattt ggttatgtca
      901 aaggttcttt tactggtgct aataaggata aattcggcat agttgcacag gctgatggag
      961 gaatattatt cttagatgaa atacacagat taccaccaga aggtcaagag atgctttttc
     1021 ttttgatgga caaaggcata tacagacgat taggagaatc tgacattgta cacaaagcta
     1081 atgtctttat tgtgtgtgcc acaacagaag atatacattc ttctctcctt gggacttttc
     1141 taagaagaat ccctgttaca attaacctac ccgctttaca ggataggtcc ttaaaagaaa
     1201 gattatctct tattaaatac ttctttatta tagagtcaaa atataccaac gcaactataa
     1261 gagttcacaa agatgtaatt aaatcattac tcctttacga ttgttttggt aatataggtc
     1321 agcttaaatc tgacatacag cttatgagtg caagagcctt tttaaattac aagactggac
     1381 ttaaggataa tatagaaata gatttatccc ttgttcctga ttacatctat attggtcttt
     1441 taaaattgaa tgaaaatcgt agtaatttaa ataaattatc agaaattgat tatatgcttt
     1501 tttatgaatt taatggtaac aacttagaag ttgaatatac aaaagaacta tctaaataca
     1561 atatagatac atcaaacaat ggatttaaat actctacaga gattccttat ctggaaaatg
     1621 atataaggag catgtttata aattacatgg aaaaatactc tacaaaatta ctttcgatat
     1681 cttcagtaac tcattctgat tatacaagta atgaaatttt taaagtaatc aatccaaaga
     1741 tttactatgc tgttgaacat tctttaaaag aggctgaaaa aatatcgaga aacaaatata
     1801 caaaacaaac ttatattgct ctttcaatgc atataagtgc acttatagaa aatataaatc
     1861 aagacacata taatcctaag tacaatttat ataatgataa aattttctta gataaagatt
     1921 taaatatagc taaaatagtt ttaagtataa ttgaaaacga cttacaaaca tctttaccta
     1981 aagatgaagt aaaatttata tccatgtttc taaatagcac gtatcttgaa ccaaacaatc
     2041 aatctgaaag tataggggtc ataatactcg ctcatggaaa ttcaacagca agcagtatgt
     2101 gtgatgtagc aaattcattg cttggtacaa accattgtaa tgcaattgac atgcctcttg
     2161 atgtaaaagt aagtactata cttgataaag ctatagaatt ggtaaaagaa tgtgacgaag
     2221 gtaagggtgt acttctttta acagatatgg gctctcttat agcttttgga gaacttattt
     2281 cagaaaaaac aaaaatcaaa actcgctcaa ttgaaatggt atctactcca atagttttag
     2341 aagcagtaag aaaaagtaca ctaccagaaa tgactttgga tgaattagct aattccttaa
     2401 gctctttaaa tccatatatt ggacgagcag caattgattc aacagaaata agctatcctg
     2461 aaaagtcaag agagtatgta ataataacga cttgtataac aggatatggt tcagctatga
     2521 aagtagcaga ctttataaat tcttcactta agaatattag taaatacaat attaatttag
     2581 ttcctcataa tatagaaagt tttaaaatgt ataagaacaa atttagtaat aataaaattc
     2641 tggcagttgt tggaagtgta gattttaatg tagccaacac cccttttata cacatagaag
     2701 aactactaaa tggatatggc ctagatatgc taaacaaaat aatagagggt acattcaatg
     2761 ccaatagtat taccaatata aaagaaacaa atctatcata taacagctta ataataaact
     2821 ttatgaccca aaacttagag cttttggact ctgttaaatt attcaactat gtcaattctt
     2881 ccttacttac aataatagaa ttaatagatg aagaattaaa gagcaaattt aagctaggat
     2941 atatactaca ttgctctttt atgatagaaa gatgttttaa aaatacaact tttccatata
     3001 ataacattac tgaaataatt agtaaaaatc atgaactata tagtttaata cgtgaagcct
     3061 ttaagccaac agaagcttat tttaatattt ttataccaga cgaagaaatt gcttatataa
     3121 tagacatgat taatgaatat ctaaataaat aaaacttata gcacttattt tgtgcatgtt
     3181 aattaatata tgaaatggag gatgagattt tgaaaggaaa aataaaacag ttaacaatac
     3241 ttacattaat ttttatattt ataactcctg gatttgcatt tgcagatact ccaccagtac
     3301 caaactcttc aagagcagca ctacttatag accaggaaac taaaagaata ttatttgaaa
     3361 aaaacattga tgagaaaatg ccattagcga gtttaagtaa aatgatgacc tttttattgg
     3421 caatagaagc aattgataag aatcaagtaa aagagactga tatggtgaaa atagacaagt
     3481 ctacagcttc agtaggaggt tctacttgta aacttaaaga tggtgatgaa atatctctag
     3541 gagaacttat gcagggtctc atgctagtat ctggaaatga tgctgctcta gccatagcta
     3601 agcatattgg taaaactgaa aagaattttg taaatatgat gaacaagaaa gcagaagaaa
     3661 taggaatgat tgatacgtat tattttaatc caaatgggct tcctatatat actgacccag
     3721 agcataaaga gcctcctatt gagaatatat caacagctca cgatatagtt acacttggaa
     3781 agtatatgta tgaccattat gaaaaccaag ttacaagaat aaccactatg caagtatata
     3841 atgatactaa aaaagatttt acacattata acacaaatcc tctacttgtt tcagtacctg
     3901 gtgttgatgg aataaagaca ggctacacag ataatgctgg atattgtctt gcattttcta
     3961 tgatgatacc taaggatgct aaaaacgaaa gaaatcatag attaataggt gttgtacttg
     4021 gtgatggtaa caagaaaaat agaatttctt cttctgctag tctattgaag tatggtaaag
     4081 ataatttcca ttctaaaaag atagcacata agggggatat tatagagact ccttgtgttg
     4141 atggtattga tgattttaag ataaaagtta aggttgataa agatttgtat ggtgttgttt
     4201 cagataacga gaatatcaat ccgaaggtag tatttaaaaa tatgaattat cctatccata
     4261 aaggagatat tgttggtgtt gcaaagtatt ataatgattc tggtaaattt gttggaagtg
     4321 tcaatgtaaa aagtgaaagt aatataggat gtattccttt gaaagataag attaagatta
     4381 gggttgctaa gataaataga aagcttgatg ttaaaaattc tgtttgtttt aaagtatagt
     4441 aaggcatact attaaaaaag tgtgttaaat ttataagact ccactttgtg gagttttttt
     4501 gttttttaca aaaaattaaa atagtggcaa caattgagga tgtgagggag agttgccact
     4561 attttgtata gggtattata ttatgttttt aagctagttt tactatcttc tatgtttata
     4621 taataactct tgtgtgtgaa tttaatagat aattcatatg aaaattatgt gaagttttgg
     4681 gtttttaaat aaatttttat ttaaataata cacataaata tttcaatact ctaagtttta
     4741 aaatactata gagtagcaga ttttatttaa aaaatttgct actcttggat attaaaaagc
     4801 tgtaggaaaa ttattttaaa aatcctacag ctaatattag tatatacaag aagatttact
     4861 ttttttgaaa ctagttttta attatgctta attatttatc tcaagatgtt aaataaactt
     4921 gatagtccag aagatatttt tcctattgtt gatattggag ctgccacatg ttttttaact
     4981 tcaaatgttg catttgctac tgaatctgta gcagttgttt cagatactgc tcctgcttta
     5041 actaacacac ttacattat
//
LOCUS       DBGJFK010000123         4681 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.131, whole genome shotgun sequence.
ACCESSION   DBGJFK010000123 DBGJFK010000000
VERSION     DBGJFK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4681
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.131"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(40..1224)
                     /locus_tag="ACOIAP_003483"
     CDS             complement(40..1224)
                     /locus_tag="ACOIAP_003483"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGZ2640354.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMENNGIKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCKYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPIFIDTKKENDFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYSGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKAIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSTDIDNMVKTYKSRRDLIKSKLDSIENIGYVNPNGAFYAFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLNKLKEFVYKI
                     MA"
     gene            1597..3948
                     /locus_tag="ACOIAP_003484"
     CDS             1597..3948
                     /locus_tag="ACOIAP_003484"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HGZ2640355.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDEELVNKMQNFAFEESYKETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDELGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRDKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            3970..4509
                     /gene="nrdG"
                     /locus_tag="ACOIAP_003485"
     CDS             3970..4509
                     /gene="nrdG"
                     /locus_tag="ACOIAP_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGZ2640356.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEVIAREAKTNGLDVWSYTGF
                     TFEQLLDKRNSAYFKNLNLLKQIDILVDGKFVAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         1794 a          553 c          774 g         1560 t
ORIGIN      
        1 cccatatatt gtatcaatta ctatttattt aaattgttat tatgccatta ttttatatac
       61 aaattctttt aatttattta atccagataa gaatgtattt tcactgcaag cataagatat
      121 acgaatatat ttatccatac caaatgctat accaggaaca actgcaacat tatattcttc
      181 taaaaattga ttacaaaatt ctatagaaaa actatcttta tattcaaatt tctcagatac
      241 tttagaaagg tctataaatg catagaatgc gccatttgga ttcacatatc ctatattttc
      301 gatagagtct agttttgatt taattaaatc tcttctagat ttatacgttt taaccatatt
      361 gtctatgtca gttgagcaat ctttcaaggc tccataagct atgtattgtg ctgtcaaact
      421 tgggtgagat ataagatgtc cttgtataga actcattgct ttagcaatcg ctttattaga
      481 tgcagtatac cctaatctta atccagtcat tgcagctgac ttagaaaaac catttatagt
      541 tattgttata tctttagctt cttcgcttaa tgatgcaatt gatgtaaatt cgccactgta
      601 gcatattttt tcatatattt catctgctaa aatatatatt ttattttgta tacacacatc
      661 tactatttct attaattcat cttttgtata aacactacca gtaggatttg aaggattgtt
      721 tattacaaga atttttgttt tatctgttat agatttttca agttcttctt ttgtcagttt
      781 aaagtcattt tcttttttag tatcaataaa aattggaaca gcattaacta acttaaccat
      841 ttcaggataa ctaacccaat aaggttttgg caataagact tcatctcctt cgtctgttaa
      901 agctagtaaa gtatttgtta ttgagttttt tgctccgctt gatacaacta tttcgtctat
      961 tgaatattta cagttgtttt cctcaataag ttttttacat atttcttctc taagtatttt
     1021 taatcctgga actaaatcat atttagtgta atctttattt aaagaatcaa taccataaga
     1081 ttttgcgtta ttaggtacat taaaatcagg ttctcctata ctaagattta ttactttaat
     1141 tccattgttt tccatttctt taactttaga actaatacct attgtgtagg atggtgttat
     1201 aaagtttagt ctttttgata acataaaatg cctcctttta aattattatt tatattatac
     1261 gacaatttta aagaatttac ataaggaaat ttgtagatat atacattaat atatataata
     1321 gaatacactt tttgcctaaa attagtgtaa aaaaaagaga aaaaaatttt gactttcaaa
     1381 gttgttagaa acgctactgt tcaaaatatc cacatagtat ttgcaatgat ttgcgcaagt
     1441 ttgactatta tgtacaaatt tggtaatctt aatatagtaa ttattaagat agtcccttta
     1501 acttagttga aggggatttt tttagactta atatactaca tatagtggta tgtggattaa
     1561 caaaatacaa tatatagtaa caggaggttt ttttaattgg ttgaattcgt aaaaaaaaga
     1621 gatggaagag taattccatt taatgaagat agaataacaa gagctatatt tttagcagca
     1681 acgaatgttg cagaaagaga aggaatagta cctgattata aattatctga gcaattaact
     1741 caagaagtaa taaagttttt aaatcataaa tactcagaat cagttccaag tgttgaagat
     1801 atacaagatt ctgtagttaa ggttcttata gaaactggcc atgcaaaaac tagtgaagaa
     1861 tatataatat acagaactga aagaagtaga ataagaaatt caaaaacaag attgatgaag
     1921 gcaatagagg aaattacctt tgaagatgca gaagatgctg atataaaaag agaaaatgca
     1981 aatattaatg gtaatacagc aatgggaact atgttacaat atggaagcac tgtatctaaa
     2041 gaattttgta aaactcatat attaaaacca gaacattctt ttgctcatga taatggagat
     2101 atacacatac atgatatgga ttttttaaat atgggaacat taacttgttg tcaaatagat
     2161 gttaaaaaac tattcaatgg tggattttca acaggacatg gttttttaag agagccacaa
     2221 gatataataa gttatggagc attagctgca attgctatac aaagcaatca aaacgatcaa
     2281 catggaggtc aaagtatacc atttttcgat tatggattgg ctgaaggtgt atataagaca
     2341 tttaagaaat tctacatagg aaatttagct aaagcgttga agttatttaa aggaattgaa
     2401 aataatgatg tgataaagaa catagtatat aatacagaga aagaaacaaa tcaaaaagtt
     2461 ggtcttaaga gagatgaatt gtatctaaac ttagaaaaag agaaattaat acagactttt
     2521 gatatagatg aggaacttgt aaataagatg caaaactttg catttgaaga atcgtataaa
     2581 gaaactgata aaaaaacata tcaatctatg gaagcattta tacacaatct aaacacaatg
     2641 cactctagag caggtgcaca ggtaccattt tcaagtgtaa acttcggaac agatacttct
     2701 gaagaaggaa gaatggtaac taagaatctt ctattatctc aggaaagagg tttaggtaat
     2761 ggagagacac caatttttcc aattttaata tttaaggtca aagaaggcat aaatttaaat
     2821 cctgaagacc ctaattatga tttatttaaa ttatcatgca gagtatcagc taaaagacta
     2881 ttccctaatt ttagtttttt agatgcacct tttaatgcaa aatattataa aaaaggtgaa
     2941 ccagatacag aggctacata tatgggttgt agaacaagag tacttagtaa tgtgtgtggt
     3001 tcagaaaccg ttagtggtag aggaaacata tcttttacta cagtaaattt accaagattg
     3061 ggtataaaac atggtattat aaataatgaa aaggctaatt tagatggttt ctttgaagaa
     3121 ttagatgaga agataaactt aattatagaa caattattgg aacgtcttga ggttcaagga
     3181 aataaaaaga tgaagaattt tccattctta atggggcaag gtgtatggaa aggttctgat
     3241 gaattaggtc cagaagatac attaaaagaa gtaataaaac aaggaacatt gacaattgga
     3301 tttataggtt tagcagaatg tcttattgct cttataggta aacatcatgg agaaagtaaa
     3361 gaagctcaag aattaggctt aaagatagtg tcacatatga gagataaaat ggatgaagca
     3421 acagacaaat ataaattaaa tttctcttta atgggtactc cggcagaagg tctttcaggt
     3481 agatttacta aaatagataa aaaagtttat ggggaaatta aaggtattac agataaagaa
     3541 tactatacta attcattcca tgtaccagtt tattacaata taagtgcata tgataaaatt
     3601 gagatagaag ctccatacca tgaattgact aatgcaggtc atataacata tgtagagtta
     3661 gatggagatc catctgataa tctagaagct tttgaaactg ttataaaggc tatgaaagat
     3721 ttaggtatag gatatggaag tataaatcat cctgtagata gagacccaat atgcggtttt
     3781 tcaggtgtaa taacaagtaa tatatgccct gtatgtggaa gaaatgaaga tgaaagtgac
     3841 atcaaattcg aaagaataag aagaataaca ggatacttag ttggtacagt tgatagattt
     3901 aataatgcta aaaaagcaga agtaagagat agagtaaaac atagatagtt ttatttgggg
     3961 gaataagtta tgaaaataag aatgtcatct actataagtt atgacagcat agttgatgga
     4021 ccagggttaa gaatggtgat atggactcaa ggatgtattc ataattgtaa agagtgccat
     4081 aatcctcaaa cgcatgattt atgtggagga ttttatatgg atacagaaga aattataaat
     4141 aaagtaaaat cattgaaatt acaaaaaggt attacgctat caggaggaga accattttta
     4201 caaccagaac cattagaagt aatagcgaga gaagctaaaa caaatggact agatgtatgg
     4261 tcatatactg gatttacgtt tgaacaactg ttagataaaa gaaatagcgc atattttaaa
     4321 aatttaaatt tactaaaaca aattgatatt ttagtggatg gaaaatttgt agctgaaaaa
     4381 aaagatataa gcttaaaatt tagaggttca tcaaatcaaa gaataattga tgttcaaaaa
     4441 agtttgaaat ataaaaaagt gtttttggtt gaacaatata tgaaagatga tttgtctata
     4501 gcagaataaa atataaataa acaggagtaa atatatgctt atatttactc ctgtttattt
     4561 gcatataata tttcaagctt gtatgatgta acaatcaaac caaaatactt attgtatatc
     4621 tgaaattaag ttttttatag tttagaggtg ttttatgtat attacaaagg gtataccata
     4681 c
//
LOCUS       DBGJFK010000124         4673 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.132, whole genome shotgun sequence.
ACCESSION   DBGJFK010000124 DBGJFK010000000
VERSION     DBGJFK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.132"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            158..1090
                     /locus_tag="ACOIAP_003486"
     CDS             158..1090
                     /locus_tag="ACOIAP_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rossmann-like and DUF2520 domain-containing
                     protein"
                     /protein_id="HGZ2640357.1"
                     /translation="MGFIGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKT
                     KIYSNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSK
                     KAGALIYSIHPIFAFSNKNTDLKKMKDICFSIEGNNEQGDLVIQNFIDSLGNQFFIRD
                     KDTSSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAITPLVEKNIENILDNG
                     FTKALTGPVSRGDITPIMKHLSVLDKKDEEIYKILSLNLLKITALGNDNLLKCTKNIT
                     IENAVENLISKSEKYKKIYKLLGGKNDEKYYTDF"
     gene            1065..1892
                     /gene="panB"
                     /locus_tag="ACOIAP_003487"
     CDS             1065..1892
                     /gene="panB"
                     /locus_tag="ACOIAP_003487"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HGZ2640358.1"
                     /translation="MKNTILTFKNAKYEGKKLSMLTAYDYSMAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDTVKNAGR
                     LVKEGGAHAVKLEGGSNIIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKIQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMRDSIKNYILEVKTGAFPQEKHSFSINESELEKLY"
     gene            1911..2759
                     /gene="panC"
                     /locus_tag="ACOIAP_003488"
     CDS             1911..2759
                     /gene="panC"
                     /locus_tag="ACOIAP_003488"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HGZ2640359.1"
                     /translation="MLVKEIKLLRNIIKDWRKDGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIERDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPIHFGGVCLVVSKLLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNRSLSLAKEELVKGNLN
                     PKNIKELITAKINSEHLAKIDYVEIVDSETLQPVGQIENSVLVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3122..3304
                     /locus_tag="ACOIAP_003489"
     CDS             3122..3304
                     /locus_tag="ACOIAP_003489"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640360.1"
                     /translation="MFKDKIDECIHIMTAYIASLKEYYSFIETQIGDFIKKYGEDTVE
                     LCLHRIMILLCECGLA"
     gene            3609..4523
                     /locus_tag="ACOIAP_003490"
     CDS             3609..4523
                     /locus_tag="ACOIAP_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HGZ2640361.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTSKDYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSAAEQKTEEFTGIEINKNITT
                     RELNLQSGVDPEVGQDLVNYVAQLNSDAIRLLDGLINLKERVLDGVLSCTLFTSNYPL
                     LLEHIIHEANLYRSYIVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFALKFNKLIEKANEMTDSNIKSITEETLNETVEFKDFKEEGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
BASE COUNT         1863 a          542 c          721 g         1547 t
ORIGIN      
        1 ttttttatga aaatggtaat atatttatgg atggtatctt gttataagaa ctatacttta
       61 aatgttttta attattttgt cttatgtaac tcatatcctc aggaatgaga ttagaaatta
      121 agatgttgta tcacaaagtg gaggtgatac tattaaaata ggttttattg gttctggaaa
      181 agttggaaca tctttagcta attatttttt gtcaaaaggt tattgtgtat caggctttta
      241 tggaagaaat caattatctt tactagaatc aacaaattta acaaaaacaa agatttacag
      301 caatttgaaa gatataattt atgaaaacga tatattattt attacaacat cagatgattc
      361 tattgaaatt atagacaaaa aactttccaa atttaattta aaacataaat atatttgtca
      421 cacaagtggc tctttaaaat ctagtatatt gttctgttca aaaaaagcag gtgcattaat
      481 ttattctatc catcctatat ttgcattttc caataaaaat actgacttaa aaaaaatgaa
      541 agacatttgt ttttccatag aaggtaataa tgaacaaggt gatttagtta ttcaaaattt
      601 catagatagt ttgggaaacc aattttttat aagagataag gatacttcat ctacttatca
      661 tttagctaat gttttagttt caaatttagt attatcttta ctagatatag gagtaagtta
      721 ctttatcaaa ttaggtttat ctgaagagga atctttaaaa gccatcactc ctttagttga
      781 aaaaaatata gaaaatatac ttgataatgg ctttactaaa gctcttactg gtcctgtttc
      841 tcgtggagat ataacaccaa taatgaaaca tctatctgta ttggataaaa aagatgagga
      901 aatttataaa atactctcct taaatctact aaaaataact gccttaggaa atgataactt
      961 attaaaatgt acaaaaaata ttactataga aaatgcagta gaaaatttaa taagtaaatc
     1021 tgaaaaatac aagaagattt acaaactttt aggaggaaaa aatgatgaaa aatactatac
     1081 tgacttttaa gaatgctaaa tatgaaggaa aaaaactatc tatgcttact gcttatgatt
     1141 attcaatggc aaaaataatg gatgaatgtg atataaatgg cattttaata ggagattcgt
     1201 tgggaatggt aataaagggt gaagaaaaca ctctatctgt tactatagat gaaattatat
     1261 atcatacaaa ggctgtaaaa aatggcgtaa aaaatgcctt aatcgtaagt gatatgcctt
     1321 ttttatctta ccatgtttct atagaagata cagttaaaaa tgctggtaga cttgtaaaag
     1381 aaggaggagc tcatgctgta aagttagaag gtggctcaaa cattataaag caaatagaaa
     1441 gcattgtaaa tgcccagata cctgtaatgg gacatttagg attaactcct caatcagtaa
     1501 attcatttgg tggatttaag attcaaggaa atactagtga aacagcaaga caacttattg
     1561 aggatgctaa attaatagaa aaagcaggtg cattctctat tgtccttgaa ggagtgccta
     1621 cgaaaatagc tgagatggta actaactcta tttcaattcc tacaataggt ataggagcag
     1681 gaattaactg tgatggacaa attttagttt atcaagatat gttgggaatg tttggagatt
     1741 ttgttcctaa gtttgtaaag cagtatgcaa atataggaga tataatgagg gattcaatta
     1801 aaaattacat actagaagtt aagacaggtg cattcccaca agaaaaacac agcttttcaa
     1861 taaatgaatc tgaattagaa aaattatact aatattaagg atggtacaaa atgcttgtaa
     1921 aagaaataaa attactaaga aatataatca aagactggag aaaagatggc tattctatag
     1981 ggcttgttac aacaatggga tttttacatg aaggacacca aagtcttata aaaaaagctg
     2041 taaaagaaaa tgataaagta gtagtgagcg tatttgtaaa tccaactcaa tttggaccaa
     2101 atgaagattt taatagctat ccaagagata tagagagaga ttttaaatac tgtatggata
     2161 gcggtgcaac agtagtcttt aacccatcac cagaagaaat gtatttaaaa ggtaattgta
     2221 ctaccatcaa tgtttctgga cttacagatt ttctttgtgg agctaaaaga cctattcatt
     2281 ttggaggtgt ctgcctagtt gtttcaaagc ttctaaatat agtaacacct gataaagctt
     2341 attttggaga gaaggatgcc caacaattgg cagtaattaa aaggatggtc aaggatttaa
     2401 atatagatac agaaataata ggttgcccta taattcgtga aaatgatgga ttagcaaaaa
     2461 gttcaagaaa tacatatctc tctgaggaag agcgaaaatc tgctctaatc ttaaatagga
     2521 gcttaagttt agcaaaagaa gagctagtaa aaggtaatct aaatccaaag aatataaaag
     2581 aattaataac agctaaaata aattctgagc acttagcaaa aatagactat gttgaaattg
     2641 tagatagtga gacattacaa cctgttggac aaatagaaaa ttctgtactt gtagcaattg
     2701 ctgtgtttat aggaaaaacc agactaattg ataattttac atttgagtta aatatatagt
     2761 ctgcaatttt atataataca tctaaaaaat aataaattgc ttagaaaata atagattaca
     2821 ataactaaaa ttttaaaact aaattcctta aaaatatgat taattgtaat tatatatgta
     2881 tactattatt acacttatat taatctatat taaacctcta ctaatttaag taaaccttta
     2941 actggataat ttttccttta aaaatgaaaa tttatccagt tttgcgatta taataaccag
     3001 ttttacatat ccacttgtaa aatatatcta agcaatatat catactatat agatttgtga
     3061 gtgaaataat atctgctatt tactgaatat ttttattttt cgttttttag ggggattagt
     3121 tgtgtttaaa gataagattg atgaatgtat tcatataatg actgcatata ttgctagttt
     3181 aaaagaatac tattcattta tagaaactca aattggtgat tttattaaaa aatatggaga
     3241 agatactgta gagttatgtc tccatagaat aatgattcta ctatgtgaat gtggtttagc
     3301 ataaaattaa atacattaaa gtgggtaaga agagtcctat gtaaaactcc tcttacccac
     3361 tttaatatgt agacttagtt taatctaaat aactaagtta taaaatcata ttataattta
     3421 taataagaag caggttaata aatcaaattt gttttataat ccaacataaa tattaagaaa
     3481 aaggatgtaa taagattctt gttgatatta gtgtcaattg aatttagtta atttatttat
     3541 aatatacata aatttaaata ttacgaatag agtattataa ataggatact ttctaaaggg
     3601 aggaaattat gatagataat caaaaatatg ttattttatc actagaatta cacttatttt
     3661 tttcaagaat tatgaaagag catgctcttt ttttagaagc aggatttaca agtaaagatt
     3721 ataatcttgc tatggaagct gaccactata aaaagcaatt tgaagattta ttatcataca
     3781 cggttagtgc tagtaatggt ataattagac ctgatatatt atattcagaa gaacttgtaa
     3841 ctactcttac atcagctgca gaacaaaaaa cagaggagtt tacaggaata gagataaaca
     3901 aaaacataac tacaagagaa ttaaatctac aaagtggtgt agacccagaa gttggtcaag
     3961 acttagttaa ctatgtagct cagcttaact ctgatgcaat aagattactt gacggactta
     4021 ttaatttaaa ggaaagagtc ttagatggag tactatcatg tactctattt acctcaaact
     4081 atcctctact tcttgaacat ataatacatg aagcaaattt atatcgttct tatatagttg
     4141 acctcgaaaa taaaatagac attgagtcaa aaaacgctaa agaaatagaa ttattctggg
     4201 accatattat gatggaacac gctctattta tgagaggatt attagaccct tctgaaggtg
     4261 aactaataaa tacttcaaat gattttgctt taaaatttaa taaattaatt gaaaaagcaa
     4321 atgaaatgac tgattctaat attaagagta ttacagaaga aactctaaat gaaactgttg
     4381 aatttaaaga ttttaaagaa gaaggagcat caggaataga acagtgtaag ataaaatcta
     4441 taatattacc acttttagca gaccatgttt taagagaggc taatcattat attagaatat
     4501 tggagagtta taaaaacatg taattaaaaa atacttttaa aacaatattt agataaaata
     4561 aaggtacttc aactgtacct ttattttttt atacgcttat agaatttaaa caagttattt
     4621 ataaaacaaa atcataatca tctataatcc acaaatttat tttatattaa ata
//
LOCUS       DBGJFK010000125         4647 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.133, whole genome shotgun sequence.
ACCESSION   DBGJFK010000125 DBGJFK010000000
VERSION     DBGJFK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4647
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.133"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            12..680
                     /locus_tag="ACOIAP_003491"
     CDS             12..680
                     /locus_tag="ACOIAP_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGZ2640362.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     KGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYKDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGILYKNDGNKQAGIWEDDEQCKSLDFKDLSNNEISKVSQNRLNNN
                     KLRV"
     gene            839..1345
                     /locus_tag="ACOIAP_003492"
     CDS             839..1345
                     /locus_tag="ACOIAP_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGZ2640363.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLNLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1473..2489
                     /locus_tag="ACOIAP_003493"
     CDS             1473..2489
                     /locus_tag="ACOIAP_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HGZ2640364.1"
                     /translation="MGYYNDNDNNKIRRKKISNSKDSNKKSKHSYTSANKKNKSSKTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPDDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGGSTIDMQVSKNLLTS
                     DDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVNE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQLIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     regulatory      2688..2782
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00442"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="guanidine-I (ykkC/yxkD leader) riboswitch;
                     Guanidine-I riboswitches control genes whose products are
                     involved in modification or pumping out guanidine as a
                     toxic compound from bacteria; This is class of guanidine
                     riboswitches is based on the ykkC/yxkD leader; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="guanidine"
                     /db_xref="RFAM:RF00442"
     gene            2845..3549
                     /locus_tag="ACOIAP_003494"
     CDS             2845..3549
                     /locus_tag="ACOIAP_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HGZ2640365.1"
                     /translation="MKKFVIEDTFWNLFPNAKIGVIICNDIDNSIKDEDYKKIILQGE
                     EEALKYLEDSEFSKNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENLFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALSELAKIVQEKLGGK
                     CKISILDIDNKEVSVD"
     gene            3844..4323
                     /locus_tag="ACOIAP_003495"
     CDS             3844..4323
                     /locus_tag="ACOIAP_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HGZ2640366.1"
                     /translation="MSNKIIKNLLSGILQILFFLLGLVIVVGGFKSFIYLCFSGEATL
                     QGTISGILMFILGVSYFIIIKLLIEVLGSSEYSLFVKENVKRFRVIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVLVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1948 a          374 c          790 g         1535 t
ORIGIN      
        1 ggtgattttt tatggaaaat ataactagtt attttacaac aatactatgt gtatttatat
       61 gtttatcatc tgtatttata tttactcaac tagctagagt atttattaat aagaagaaga
      121 ttaatcaaaa aattaaatca agaaaaggat ttaggtatga tagagatttt attgaagcta
      181 gaagagaaga aatacatata aaggataaca ataataataa aaataagagt aacaataaga
      241 aattaaaggg agaaaaagta tttaaatatg ataatggaga tttatataaa ggtgagtttg
      301 ttgatgggaa gaaaaatgga tttggaatat atattttttc aagtaaggaa aagtatgaag
      361 ggttatggaa agatgacaag atgcatggaa taggaaaata tacttataaa gatggttcaa
      421 tatatacagg tgaatttaaa tacggattaa aaaatggttt ggggaaatta acatatccca
      481 ataatgatat ttataaggga tattttttag ataataagaa aaatggtaag ggtatattat
      541 ataaaaatga tggaaataaa caagcaggaa tatgggaaga tgatgaacaa tgtaaaagtt
      601 tagattttaa agatttaagt aataatgaaa taagtaaggt ttctcaaaac agattaaata
      661 acaataaatt aagagtttag ttattctaat aaaaaaatct ttatttatga tggaatatag
      721 aatatgttta tgctgtaatt tgtaaaatct tcctatatca tataaaatta agtattgatt
      781 agtctattac ataaatatag aatataaata tatccatttg ataataagga gaagagatat
      841 gaaagagtat gtagttgtgg atttagaaac tacaggatta gatccatata aaggttgtga
      901 aataatagaa ataggaataa cagaaataaa aaatgaacaa attgtaaaaa actattcaag
      961 gttgataaaa cctaagggga taatttcttc atttataaca gaattgacac atataagtaa
     1021 tgaaatggta gaaaatgaag aacctctaga attagtttta cctagattta gaaagtacat
     1081 aggtgataga actataattg cacacaatgc gaaatttgat ttaaaatttt taaattacta
     1141 tcttagaatg ttaaatttag aaccaataaa caattatata tgtacagtag aattattaaa
     1201 aaaatgtaaa agttataaag gaaaaaataa gaaacttgaa acagcttgtg cttattacaa
     1261 catagagaat ataaatgctc atagagctga tagtgatact ttagcaactg caaaactatt
     1321 tttgaaaata aaagatgaat attaatcata aatatagaga aaattagtga aaatatcctt
     1381 tataaaattg acccttaaac ttacaatttt gttctttgat ttattttgta gaacaatgta
     1441 taatgtacct tatatgaaga agggagacta aaatgggtta ttacaatgat aatgataata
     1501 ataaaataag acgtaaaaaa attagtaaca gcaaagatag taataaaaaa tctaaacatt
     1561 cttatacttc ggcaaataaa aaaaataaaa gttctaagac aagttctagt aaaagaatga
     1621 gcgaaaaagt agattcacag aatcttataa aaagagatag agatagtttt acaagagata
     1681 atgtaagacc tttaaataca gattataatc aaagagaaag aagaagagtc gagtataaac
     1741 aaagagagaa aaaactaaaa agtaaaaaaa gaaaaaaaca aaaaaggatt agaatagtta
     1801 gggcattgtt atctattatg ttagttgcac taattatatt ttcagtggca ggtgcaatat
     1861 ttacagtttc agctataaaa gggtcaccag aagtcactaa aaagttaatt aggtctaaat
     1921 atataagtag tgaggttgta agtataaaac aaatgccaga tgatttaaaa catgcaatag
     1981 tttccataga agatgagaga ttttataagc ataaaggagt agatgttatt tctttagtta
     2041 ggtcagtact aaacaatgtg tttacagata caacacaagg tggaagtact atagatatgc
     2101 aagtttcaaa aaatctgctt actagtgatg ataaaactat gaaacggaaa ataagggata
     2161 tgtataatgc taagcaaatg aataagatta tgactaagga tgaaattctt gaagcttatt
     2221 taaataatat gtacctaggt aaaaatgcat atggagctgc aaagggagct gaagtctact
     2281 ttggtaaaaa agttaatgaa ttaaatttag ctgagtgtgc tatgttagct ggtatgacaa
     2341 ataatcctgc aaggtatatt gaccatggag aggctaagaa gagacaattg attgtattgt
     2401 ataagatgca tcagcttggt tatataactg ataaggagta tagaatagca aaagctgatg
     2461 acactccatt taaatctgaa attgattaaa attgtaaaga tgtggtattt agaacagttc
     2521 aaacaaatga aaatgtaata aaaaaggtga tttgccaccc atctgtcacc ataattataa
     2581 tcttatggca aattgtttta attcacaaat tagataatag aatattgttt taagtgctat
     2641 agtatgctaa aatttaaaat tgtattttat aaattaaaaa aagttataac ttagttttct
     2701 agggttccgc attttataat ggtcaggtcc aagagaaaac gcacaattat tgtgtacacg
     2761 gaaggataaa agcctgggag atatttaata atatttctat aggctttttt atttttatat
     2821 attttaaatt taaggaggtt tttaatgaaa aaatttgtta ttgaggatac attttggaat
     2881 ctatttccta atgcgaaaat tggagttatt atttgtaatg atatagataa ctctataaaa
     2941 gatgaagact ataagaaaat cattttgcag ggagaagaag aagcattaaa atacttggag
     3001 gattcagaat ttagcaaaaa ccaagtgatt aaagtatgga gagaagcatt taaaaaattt
     3061 aaaacgaaaa aaggagcaag gtcttctatt gaggcattat taaaaagagt tcataatgga
     3121 aataatatag gaactattaa ccctttagtg gatatctaca attttatctc attaaaatat
     3181 gcattacctt gtggagggga ggatatagat aaatttatag gagatattag gctaactaga
     3241 gcaattggta atgaggagtt tatcccacta gggacagatg aaaatttatt tccatatgaa
     3301 ggagaaataa tctataaaga tgatggtgga gcaatttgta gatgttggaa ttggcgtgaa
     3361 gcagtgagaa caatgcttac tgaagatact aataacgcct ttttatgtat tgaattagta
     3421 gatgaaagta gatttaaaga atttgaaaat gctttaagtg aattagctaa aatagttcaa
     3481 gaaaaattgg gtgggaagtg taaaatctca attttagata ttgataataa agaagtatca
     3541 gtagattaat ctggaggtgc tgttgtaatg ggctattcta gttataaaga tacttatatt
     3601 tagggtaaga aggtctattt tagatgcaac gattatcaaa ggatatgata tagaaaataa
     3661 aaatgtggaa tataaaaagc ctttaaaata agaaaaaatt gtattttaaa ggcttttatt
     3721 atactatttt ttatttgcac aattaacaat aaaaatatat tgttaattat aatattttta
     3781 ttgaaaaaca atataatgta atgtattata ctatatataa aatattttaa aggagttggt
     3841 atgatgtcta ataaaattat aaaaaattta ttaagtggta tattacaaat tttatttttt
     3901 cttttaggat tagtaatagt tgtgggagga tttaaaagtt ttatatacct atgttttagt
     3961 ggagaagcaa ctctacaagg cactatttct ggaatattaa tgtttatttt aggtgtatca
     4021 tattttatta ttataaaatt attgatagaa gtattaggta gttctgaata tagcctattt
     4081 gtaaaagaga atgtaaaaag atttagggtt attggatatc ttttgctttt aaactctcta
     4141 attgagttta tttcaacttt tggtactact ggaaaaggaa tgagattcct agatttagga
     4201 tttggatttt attttactgt tccagtactt gtatatttta taacttctct tatgagtttt
     4261 gtaattgcag atggatttgt aaaggcaata aagataaaag aggataatga tttaactatt
     4321 taggaactat actttaatat atagaagata gataacttga aaagagaggt taactagtaa
     4381 tttaaaataa aatatattaa agtataatgc ataaactata atgctaaaat gaaaaagtta
     4441 taatgcaaag atataattat gttttaatta aacaaagaat tttattatta gatattaaaa
     4501 gcgcattttt ttataaaagt gcttttttat aatttattaa aggtttaatt ataaaagtct
     4561 tattcaataa aatttatagt taatttatat atatttgtaa ataatcaata taaaatagat
     4621 attttaataa cataaatgca caattag
//
LOCUS       DBGJFK010000126         4325 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.134, whole genome shotgun sequence.
ACCESSION   DBGJFK010000126 DBGJFK010000000
VERSION     DBGJFK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4325
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.134"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            70..666
                     /locus_tag="ACOIAP_003496"
     CDS             70..666
                     /locus_tag="ACOIAP_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HGZ2640367.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DINREEKINDIYKYLYKCKKIDFIVIDKKEKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKGDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(763..1722)
                     /locus_tag="ACOIAP_003497"
     CDS             complement(763..1722)
                     /locus_tag="ACOIAP_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGZ2640368.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNENIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDKVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(1756..2487)
                     /locus_tag="ACOIAP_003498"
     CDS             complement(1756..2487)
                     /locus_tag="ACOIAP_003498"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640369.1"
                     /translation="MVRSGFLLENICKKYLVDNKEHLVLDNVSLNISSEEITVILGES
                     GCGKTTLLRILAGLENATTGNVYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVSIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(2480..3250)
                     /locus_tag="ACOIAP_003499"
     CDS             complement(2480..3250)
                     /locus_tag="ACOIAP_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640370.1"
                     /translation="MFEKIHKKFKGYYIFFIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVVFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SRKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(3335..4015)
                     /locus_tag="ACOIAP_003500"
     CDS             complement(3335..4015)
                     /locus_tag="ACOIAP_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HGZ2640371.1"
                     /translation="MCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPSNGGGLGRALL
                     GHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESENLLAFSEQLN
                     YSVKLIGSGVISQKGLFTTHLANKTGQNQDVAIITDGNPLILEGPCCVDPDALVAWTG
                     REPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKTDSTPSDRMSS
                     GGLRIGID"
BASE COUNT         1453 a          763 c          488 g         1621 t
ORIGIN      
        1 tattgattat catttatagt ataatctaat tacttgatat taattttcat ttgaaggagg
       61 ttatctttta tgtcttgctg taattcacaa ttttgttgta aaaacaaaat tgaatcatca
      121 tatataaaat ggcttttaga agttttaggt ccagttttct taggctctaa acctgctgaa
      181 ataataaata tttcatttac tgatataaat agagaggaaa aaattaatga tatttacaaa
      241 tacctatata aatgtaagaa aatagatttt atagttattg ataagaaaga aaaaggatta
      301 aaaatattat ttgtaaacaa aaaggcatta tcagaaaaat taaaatgtaa aaaaacagta
      361 aactttttaa agtttttagg atacaaacaa aatacgaatg ttaatgctta tttagaacat
      421 ttagtagata aacttaaggg tgatgttttt cctgatgaaa taggtatttt tttaggatat
      481 cctcttaaag atgtgattgg atttatggga tatagtaatt atgaagtttc tatgattaaa
      541 tattggaaag tttatggtga cacaaaacaa tcagaggaca catattcaaa gtttttactt
      601 caccgtaaga aaatgagaaa attactagac tacataagtg tagataaaat agtaagttgt
      661 ttttaatagt gttttgtatg ataataaaaa tacaccctct tttaatatac agtttacata
      721 ataagtaagg gtgtattttc tactttaata ttttaaaata ttctaattct gattgtacaa
      781 catatcttta atatttattt tcttttgttg cattccatta gacatcaaaa attcctgtgt
      841 atcttctaat tcttttatat ccttatccgt tattttagaa ctaaagtcat accaagaata
      901 catttctttt gtttcatcta aagataaacc aacttcttta gatacaacat ccatcacttt
      961 gtccttattt tcattcatat attttaaagt ttcttcatga accttcataa atctttttac
     1021 taattcagga tatttttcag caaagtcatc acttacagca gtaactatta ttccacttac
     1081 tagaccttct ccatttacaa tcattttggc acctgaattt atcgttttca atgccactgg
     1141 acctgcaagc attgctacat cagcactttt actttctaat gcagaagcag cactaggaat
     1201 atccatattt acatattcaa catcatctat agtatagcct tctttagcaa gtgcagcaat
     1261 caacagttga tgaagtatag tcccttttgg ccctacaatt ttcttacctt ttaagtcttt
     1321 tatagatttt atattttcat tattagttat aagcatatat ccttttggtg aacgactata
     1381 aatattcgta attttaagac caacaccatt tgacgcagct attattgcag atgttcctcc
     1441 caatgcatgt aaaaagtcta gctcacctgc tgctagtgct tgagtttgct ctggtcctgt
     1501 tgtcaattca tggaagttga cttttatatt gtccttttta aattcctttc caaataaatc
     1561 atcctttttt tctaatatac taggaacatt aagtggtgat tttacataag ttaaatttat
     1621 ttccttaggt aaactagcct ctttttttgc aggttcatct ttcttatcat ttgttgttga
     1681 gcatcctaca gtcccaacca acaccattat taaagatgtc attactgcta aaatcttttt
     1741 gtttctttta atcaattaaa actcccccaa ttcccttaat atttcttttt tcaagtttat
     1801 ataatagttt ttagttaaat ctctattata ttcatcttcg acactaaact gtttaatcct
     1861 tttattttta ctaaaaacaa ttattttctt tgctatttcc atagcttctt caatattgtg
     1921 agttacaaat actacacctt ttttagtatt tttatggata cttacaactt ctttttgcat
     1981 ttttcttctt gtgaagtaat ctagtgctgc aaatggttcg tccatcagca aaatatctgg
     2041 attgaaagaa agtgctcttg ctatacttac tctgtgagcc attcctcctg ataattcatt
     2101 tggatatgag tttttaaatt tttcaagctt catcattttt aaatacttgt ctaaatcaac
     2161 tttatttcta ttatcctttt cagtatgtaa aagtatattt tcacttacat tcagccatgg
     2221 cataagtcta ctttcttgaa ataccattcc tacttttgga gtacattttt tatcattatt
     2281 aaaaaaatat acgtttccag tagtagcatt ttcaagccct gctaaaattc taagtagtgt
     2341 cgtcttccca catccacttt cgcctaatat aacagttatc tcttcactag atatatttaa
     2401 agacacatta tcaagaacta aatgctcttt attatcaacc aaatatttct tacatatatt
     2461 ctctagcaaa aatccacttc taaccattta aatcaacctg cttccctttg ctaaattttg
     2521 ttattatctt tgaaaacaga taatctgaaa gtatgcctaa aaatccaata acaaaaattc
     2581 ctaccaagac aacatcagtt ctagacatat cttttccatc agaaatcaaa tatcctaatc
     2641 ctgaagaagc tgcaataagc tctgctccaa ttatagccct gaaactatac ccaagcccta
     2701 agctaagtcc aacaacaata tccagcatag aattaggaat tattatttta taaaaaattc
     2761 tcttcctaga taaattaaaa gatttaccta cttctattaa tttattgtca caatttttta
     2821 tgcctttcaa tgtatttaaa aatattggaa aaaaggatgc caaaataata attataattt
     2881 tagattcttc acctatacca aaccataaaa taagcattgg caccaaagct agtggaggtg
     2941 tacttcgcat aaactcaaag agtggcttga aatattcata cattttttta tttactccaa
     3001 atacaactcc aagtggtata gccatcaatg aacttattaa aaaacctatc aatattcttc
     3061 ttacactggc ataaacattt aagaaaatag aaccatcata tatcatttta atgaaagtat
     3121 ctaaaactat ttcaggagga ggcagaatat agctactcca tatacccaga acgcatacta
     3181 tcttccataa aattaaaatt ataaaaaaaa tataatatcc tttaaacttt ttatgaattt
     3241 tctcaaacat ataaaactcc ttttaacata tctaccccta ataccctttt tattttttaa
     3301 tatcctaaat aataactaat ctatatcata aaatttaatc tatgccaatc cttaatccac
     3361 ctgagctcat tctatcagaa ggagtagagt ctgtttttaa accagacaat ctttcagatg
     3421 gctgtataat gactatttgt ccaggttcaa caaattccat atgataagat tctcctgaag
     3481 tctgaccgat aaaagtcttc catgacaatt ttgacacttt aggatatggt tctcttccag
     3541 tccaagctac taatgcatct gggtcaacac aacagggtcc ttcaagtatt aaagggttgc
     3601 catctgttat tatagcaaca tcttgatttt gacctgtttt atttgctaaa tgtgtagtaa
     3661 aaagaccttt ttgagatatt acacctgaac caatcaattt tacactgtaa tttaattgtt
     3721 cagaaaacgc caataagttt tcactctcaa cataaatgga gtcacctggg tcaattgata
     3781 ttacatctac atgataagca ttttgagcta ggtaaatttc accttcacct tcaacaacca
     3841 ttattggcat ttgttctcct gtcaatgacc tctgaacatg acctaataat gctcttccca
     3901 agccaccacc attacttgga cctaacagca atttttcaaa attaaaattt cctttaaaag
     3961 ctaccatagc accttttttt gcaaaaaatt taccacttcc tcttgctata cacataagct
     4021 catttgtcac ctgaacctcc catgaataaa gtcacagagt tcctgcttca cagaattttg
     4081 catactaaaa tatgtcttac taattctcca cagtctatcc ccataatttc tacggttctt
     4141 acataagcta tttattttga attgttatta gtcttaatcc ttcttttaat atatttagac
     4201 ttactttaat gattttatca tatttaatat actatataat gctgttggga acaatttatt
     4261 catcatctat cataatatta acaaatgtaa ttatttaaaa caattattcg aaggttttat
     4321 attta
//
LOCUS       DBGJFK010000127         4250 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.135, whole genome shotgun sequence.
ACCESSION   DBGJFK010000127 DBGJFK010000000
VERSION     DBGJFK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4250
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.135"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..655
                     /gene="pgmB"
                     /locus_tag="ACOIAP_003501"
     CDS             <1..655
                     /gene="pgmB"
                     /locus_tag="ACOIAP_003501"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HGZ2640372.1"
                     /translation="DGVITDTAYYHYMAWKKLAHKIGINIDTKFNESLKGISRMESLD
                     RILEFGNKKDLFSKEEKLKMSEEKNNYYIALINDITSSDILPGIESLLIDVKSNNIKI
                     GLSSASKNAINVLNHLGISDKFDFIANAAKCKNNKPHPDIFLMSAKGLNVNPKNCIGI
                     EDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYNEYMVRRII"
     gene            652..2937
                     /locus_tag="ACOIAP_003502"
     CDS             652..2937
                     /locus_tag="ACOIAP_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HGZ2640373.1"
                     /translation="MKCLFSKIDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGIRIFIDDIELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKRFEARVTRFLSISVKELAVIKYSIKALN
                     SNAKIKFVPYLDSNIKNEDSNYEEKFWNGISSNSLEYKGSILSQTKENAFNTPVFTVG
                     SMMYIKTNGEVGAISHESNYNYCENSITMDALKNEVASIEKYVSITSTRDYKENELLR
                     KCEDILNRELSKNYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     ENAKKLGLKGALYPMVTFDGAECHNEWEITFEEIHRNGSIIYAIYNYTNYTGDYKYIK
                     EKGIDVVIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNVNNNWYTNYIAKWCLDY
                     AVENILRLEKEYNECIDRNNVTREEIDFWKIISKKMYLPYDEELQIIIQNDNFLDKEF
                     IEVKDLPKENLPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWDETLSFAPKLPKEWKSYSFNINYRDNIINVDVCSDLIKIENLKGK
                     AIKIIVYGRKYILEKYIKIDK"
     gene            3163..4056
                     /locus_tag="ACOIAP_003503"
     CDS             3163..4056
                     /locus_tag="ACOIAP_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGZ2640374.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREINKADINVSKYIKYAD
                     LASKNNVQVNWKYVASIVAVLNKNKLKNVKDSQIQEVSDLFVKNFSKNNKVNKLSYVL
                     DELKFNNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKSNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
BASE COUNT         1777 a          395 c          734 g         1344 t
ORIGIN      
        1 agatggtgta attacagaca ctgcatatta tcactatatg gcttggaaaa aactagcaca
       61 taagattggt ataaatatag atacaaaatt taatgaatct ttaaaaggca taagtaggat
      121 ggaatcatta gatagaatat tggaatttgg aaacaaaaaa gatttatttt caaaagaaga
      181 aaaattgaaa atgtcagaag aaaaaaataa ttattatata gcattaataa atgatataac
      241 ttcgagtgat attttgccag ggatagaaag cttgttaatt gatgtaaaat ctaataatat
      301 aaagatagga ctatcttctg caagtaagaa tgcaataaat gtattaaatc atttgggtat
      361 aagtgataaa tttgatttta tagctaatgc agcaaaatgt aaaaacaata aaccacatcc
      421 agatatattt cttatgtcag cgaaagggct taatgtaaat ccaaaaaatt gtataggtat
      481 agaggatgca agtgcaggta tagacgctat aaactcagct aatatgtttt ctgttggtgt
      541 tggaaattat gagaacttaa aaaaagcaaa tttagttgta gattcaacaa atcaattaaa
      601 gtttgaatat atacaagaaa agtataatga gtatatggtt aggagaatta tatgaaatgt
      661 ttatttagta agatagatga gtggaagatt atacaagata agattgaaat caaagaaaat
      721 agattagcag agtccataat gagtataggt aatggatata tgggtatgag aggaaactat
      781 gaggaaaatt atagtggaga tacacacaag gggtcttata tagctggagt atggtttcca
      841 gataaaactc gtgttggatg gtggaaaaat ggatatccag aatactttgg taaaattcct
      901 aattcagtca actatatagg tataagaatt ttcatagatg atatagaatt agatttagca
      961 aaatgcaaag tagaagattt tcatagagaa ttagatatga aaaatggtat tttaaatcgt
     1021 aggtttattg taaatataaa tgataaaaga tttgaagcta gagttactag gtttttaagt
     1081 atatctgtta aggaactcgc agtaattaaa tacagtataa aagcattaaa ttctaatgct
     1141 aaaataaaat ttgtaccata tttggattca aatataaaaa atgaagattc aaactatgag
     1201 gaaaaatttt ggaatggaat ttcttcaaat tctttagaat ataaaggaag tattctttca
     1261 caaacaaagg agaatgcatt taatacacca gtattcactg tgggctcaat gatgtatatt
     1321 aagacaaatg gtgaggtagg agctatatct catgagagta attataatta ctgtgaaaat
     1381 tcaataacaa tggatgcttt gaaaaatgag gttgcaagta tagaaaaata tgtatctata
     1441 acttcaacta gagactataa ggaaaatgag ttattaagaa aatgtgaaga tattttaaat
     1501 agagaactat ctaaaaacta tgatgatata ttaaatgaac atacaaagtt atggaataaa
     1561 agatgggaaa gtgcagatgt aaaaataaat ggagataaaa gtagccaaca aggtataagg
     1621 tataatttat tccaattatt ttcaacatat tatggagaag attcgcgatt aaatataggt
     1681 ccaaagggat ttactggcga aaagtatgga ggagctactt attgggatac agaagcattt
     1741 tgtgttccag tatatctagg tgtagcagat aaggaggtaa ctagaaatct tttagaatat
     1801 aggtacaatc agttagaaca ggcaaaggag aatgcaaaaa aactaggact taaaggtgct
     1861 ttatatccaa tggttacatt tgatggagca gaatgtcata atgaatggga gataacattt
     1921 gaagaaatac accgaaatgg aagtataata tatgcaatat ataactatac aaattataca
     1981 ggtgactata aatatataaa agaaaaggga atagatgtag taatagaaat agctagattt
     2041 tgggcaagta gagttcattt gtctacaaaa aaagatttgt atatgataca tggagttaca
     2101 ggcccgaatg agtatgaaaa caatgtcaat aataattggt atactaacta tatagctaaa
     2161 tggtgtttag attatgctgt agaaaatatc ttacgattag aaaaagagta taatgagtgt
     2221 attgacagaa acaatgtgac tagggaagaa attgattttt ggaaaataat atcaaagaaa
     2281 atgtatctgc catatgatga agaattacaa ataataattc aaaacgataa ttttttagat
     2341 aaagaattta tagaagtaaa ggatttacca aaagaaaatc ttccccttaa tcaaaattgg
     2401 tcttgggata agattcttag gtcgtgtttt ataaaacaag cagatgtatt acagggaatt
     2461 tactattttg gaaatagatt tactaaagaa gagaaaaaga gaaattttga cttctatgaa
     2521 aaatatactg ttcatgaatc ttctttatct tctagtatct attctattat tgcctctgaa
     2581 atagataact tagaaaaggc ttatgagtta tactcaagaa cagctaggct tgatttagat
     2641 aattacaata atgatacaaa tgatggactg cacataactt caatgtctgg ctcatggctt
     2701 tctattgtac atggatttgc aggtatgaga acgtgggatg aaacgctatc ttttgcccct
     2761 aagttgccaa aagagtggaa aagttattct ttcaatataa attatagaga taatattatt
     2821 aatgtagatg tatgtagtga tttaattaaa atagaaaatt taaaaggtaa agcaataaag
     2881 attattgtat atgggagaaa atatatatta gaaaaatata taaaaattga taaatagatt
     2941 taataatatt tttattatgt aaatagttaa aataaattta gctaattatg tatctatttt
     3001 aactattttg tatgatagaa aactatatat tataacaata gtagtgcttt taattaaata
     3061 tatttcataa atcttcataa aatcttcaaa atttcgtaaa gaatatgtca caaaagtaag
     3121 gtatattata ttcagcagat aatataaggg aggacaatat ttatgaagaa taaaaaattc
     3181 attgttataa tactgataat atcgatttta ataggtgtat tagtgaagga atattcatct
     3241 agagagataa ataaggctga tataaatgtc agtaagtata taaaatatgc tgatttagca
     3301 agtaaaaaca atgtacaagt caactggaag tatgtagctt ctattgttgc tgtgttaaat
     3361 aaaaataaac taaaaaacgt taaggattca caaatacaag aagtatcaga tttatttgtt
     3421 aagaattttt ctaaaaataa taaagtaaat aaattaagtt atgttttgga tgagttaaaa
     3481 tttaataata gacaaaaaag attggttgat aattatatag acaaccttaa agattatggt
     3541 ataaaaccag aaagattgaa atctgataca aaatatatga agtttattga cgaaattaag
     3601 acagaagcaa tacaaaatta taaggattat aaaatacttc catctataac cattgcacaa
     3661 gccataatag aatctagctg gggtaagtca actttggcaa aacaatataa taatctattt
     3721 ggtataaagg ctgacgctta ttggaaaggt aagtcagtga ctttagaaac gaaagaacat
     3781 ttagatacaa ttatagatga taaatttaga atatatgatg ataaaaatga atctataaaa
     3841 gaccatgcaa aatttttagc cacaaataaa agatataaat cgaatggtgt atttgatgca
     3901 aaaacatata tatatcaagc taaagcattg gaaaaggcag gttatagtac tgcaaaggat
     3961 gaaaatggaa atagcatata tgcagctcgt ctaatagaat taattcaaca gtataatctt
     4021 caattaatag acagtgaaat tcaaagtgaa atgtaacttt gattaaactt ttattgataa
     4081 ggctatgatt tttaaaatca tagccttatt ttgatatgtt ttcacttgta attattaaag
     4141 cgatattatt atctttcaaa atttctttta cagtacaaat caaattatct aagttaaaac
     4201 ttggagttat ttataaaagg attatttatt ttatataaat tttgcattta
//
LOCUS       DBGJFK010000128         4162 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.136, whole genome shotgun sequence.
ACCESSION   DBGJFK010000128 DBGJFK010000000
VERSION     DBGJFK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4162
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.136"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(29..1801)
                     /locus_tag="ACOIAP_003504"
     CDS             complement(29..1801)
                     /locus_tag="ACOIAP_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HGZ2640375.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKAIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYAFVLYSMDKHPALDSMTRRIVNDIRNIDTK
                     QDIMEVLKELDVIYLTYFEYILNEEESSLIDENNVKNVEVDFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKSSNLADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRSVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKTRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSLKNSENIFEYFCAGNNRDGLAIKSICSGLINRYEENKILIVLSDGRPNDIKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(1815..2744)
                     /locus_tag="ACOIAP_003505"
     CDS             complement(1815..2744)
                     /locus_tag="ACOIAP_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HGZ2640376.1"
                     /translation="MNIIDNLRAQGVDEKLIEDVMYFRNYYGLEKDLEYRVTRSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIQFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            complement(3150..3758)
                     /locus_tag="ACOIAP_003506"
     CDS             complement(3150..3758)
                     /locus_tag="ACOIAP_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HGZ2640377.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVVSSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(3935..4051)
                     /gene="rrf"
                     /locus_tag="ACOIAP_003507"
     rRNA            complement(3935..4051)
                     /gene="rrf"
                     /locus_tag="ACOIAP_003507"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1353 a          761 c          399 g         1649 t
ORIGIN      
        1 tgtatataaa ttctttttta caaacttatt agtttctaat tatcttcttt aaatacattg
       61 aaaccacatc agaaaatcta gttatatctc ttgaatatat aaaatcattt ccatatatca
      121 atctttcagc ttcaagttct gattctttac ctgtaaacac tcctaatact aatatatttt
      181 gctttctagc ttttctcact tcattggctg tatctctcag tccaactata cctctataag
      241 ctttttctcc tctcaaagtc ctctcactac tttttcctat ctttatatca tttggtcttc
      301 catcactaag aactatcaag attttatttt cttcatatct atttattaga ccactacata
      361 tagattttat tgccaaacca tctctattgt taccagcaca aaaatattca aatatatttt
      421 cactattttt tagactatca tcataatctt taaatctttt taatatagta tagtctaaaa
      481 aactagaaaa tcccattact ctatttggta tgccaacttc tgttagagca tttgcaatta
      541 tgtaagcttg aattgccaca tttccttgat ttctactttg agagccactt gcatccaata
      601 atatatcaat aacgtatttc cctttttcat tttctatatc tttataaaat attttattat
      661 tattacttct accaactctc caagctctat ttgctaatat agtaccacaa tcagaatata
      721 ctctagtttt agcattttct tctattaaaa ttcttgacag actttctttt aatctcttta
      781 tttgctgtct atacattcta gcatgttctc taaattttcc taaattattt tctttttgtc
      841 ttgttacata ttttagttga aatacattat tacactcact tctaagaact ccatctgtaa
      901 agtgtattct acaaccttca tgaacacttc tacaattttg tgtctcaatt tttttaattt
      961 cacctttact caaataagtt tttccataat aatgttctat ttttgaatat atcttatttg
     1021 cagtgtcttc atcaacatat ataactcggt ctgctaaatt gctagatttg gaatcatcaa
     1081 aatcccctac accttctaca agcatggatg aagatatcga atctatatca ctttcaataa
     1141 tattttcttc ttcatcacta taaagttctt catacatgaa atcagcaaat gtatcaaagt
     1201 ctacctctac attttttaca ttattttcat caataagact actttcttct tcatttaata
     1261 tgtattcaaa ataagttaaa tatataacat ctaattcttt taaaacttcc ataatatctt
     1321 gtttggtatc tatatttctt atatcattaa ctattcttct agtcatacta tctaatgctg
     1381 gatgcttgtc catactataa agtacaaatg catatttaat tttatccata atattatcat
     1441 tgtgtatttt ggtaaaacgt gaaacaatat ctttataagc atttctcctt atgtcttcta
     1501 ttcctggtct atctttaata gccttttctt caactattgt atttaatatt acttgaatta
     1561 gacccagtat aatatctttg ttgtatcctt ttcttattct atttgtaaga tattttttaa
     1621 ctatatccca atcaacatac tttcttctag cacctgcaat tattgcaaaa tacagaccta
     1681 tttcctttga agaataatct ttttctgata tatctatact ctcattgtag tcgccagcta
     1741 ttgtccagga taagttattg gctctatttt caaattcata atcatcatat atccatttca
     1801 taatctcacc tatattaaat atgacttatt ggaaacacat ctatactctc ccatttatta
     1861 ggtattctag ttttaattac atctccaacc atttctttct catacacatc aaaagtcttt
     1921 cctgtaagcc ccatattaat tgcaagggtt ggttttaagc ctcttcttat ggtcttaaga
     1981 gatgccataa gaccacgtaa atcaatagct ttactagata tctcgccatt ttgagacttc
     2041 aattgtaaat ctaaaaatat tcctgcaaat tgtattaatt tttcttcatc agcatctgaa
     2101 aattcatttt ttaaaatcat cattaactta tcttcttcta taggaggaat atctattacc
     2161 ataaatctag ataccaatgc ctcattaagt tcttttgttc ctgcatattc ataattcata
     2221 gtcccaataa atcttgttgc aggatgtaga tttactctct catacccagg tacatcaatt
     2281 atccttctat agtctaaagc tgaatgtacc acaactatag catcattttt tgccatatta
     2341 atttcatcaa ataccccaaa acctccatta atagcacact cataaactga acctcttcta
     2401 agtttaactt cattgtctat aaacgtatct gtacctataa gtgttgaact atctgtgttt
     2461 atatgaaatg atgtattcca ctgaggtcta ttaaatattt cccctaaatt atcagcaagt
     2521 aggttttttc ctgttgcctt tggtcctgat aataatatat tttcttcctc taaaatcgct
     2581 gctatacaca tagataatat gtcttttcca taaaaataag ttttagacct tgttactcta
     2641 tattctaaat ctttttctag accataataa tttctaaaat acattacatc ctcaataagt
     2701 ttttcatcta ccccttgtgc ccttagatta tctattatat tcattcttct tacccctttt
     2761 atataaatag tatttgtttc atttcttaac accattttag cataaaagga tataagctag
     2821 aattgatttc ataaattaat gacaactctt cctctctttt aaaaaaaact acctatatgt
     2881 actttttatg tattattttt gttaaatgtc tgaaagttat cagattacta ttcattacag
     2941 gatttataag ttgaggcttg tgaatgtatt tgattactat atattgttct agttttgaat
     3001 ttattatctt gacaatattt catctgtttt acatcaaaaa tccccgcttt catatagaac
     3061 tagaaacggg gattttgatt attataaatt ttctcaaaca tatgaacttt agaatagctg
     3121 tagaaaaaga tacaaaactt tttcatttct tataatctta tcttgtgatg ttttttatgt
     3181 ataaatgact taataacaaa tccaataaaa attatggata ttggtataat tagaactagg
     3241 aatttataat cattataatg tgacattatt cttacccaac tctcagaaaa aatataccct
     3301 atactgatta atgaagtatt ccatatggtt attcccacga tagatgatac tacaaaagtt
     3361 ataatatttt gacctgctat acctgctata aaagatatgt atgttctaca taaagggatt
     3421 aatctacata cacaaacaga aatagaagag tatttattaa aataatcttg agatgcaaat
     3481 attcctttct ttgcctttgg acatatctct attattttat ttataataga tttacctccc
     3541 caatttccca ctgtataaca aaatatcgaa ccaagtatac ctgcaattat acttaaaatt
     3601 aaaattgtca aaaatccaaa atgatttctt gcagcaattg ctccacataa aggtaaaaca
     3661 acttcgctag gtaatggaaa acaagcatac tcaatcataa ttaatacaaa tacagagatt
     3721 aatccatatt gtaaaataaa actattgatt acagacactt acttatctat ctcctttctt
     3781 atttaaaggt tttaagggta catattctaa ggattctcac cctatattta aagaatcaat
     3841 ctctttaaac tattatatgt atttacagaa agcatttata acatacttta aaaatagtac
     3901 cttaaaataa gaaacttaat aaataaaaaa aattacgtgg ctacgtccta ctctcccagg
     3961 cagtttccca ccaagtacca tcagcgctag agagcttaac ttctgtgttc ggaatgggaa
     4021 caggtgtatc ctctctgcta ttgtaaccac ataatcttta tgcttaatat ttctattaag
     4081 tttttaataa gtttatagaa tctagtaata ctagtccttt tagagttaac actctaaaaa
     4141 ctacacatat atcttagtaa gt
//
LOCUS       DBGJFK010000129         3840 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.137, whole genome shotgun sequence.
ACCESSION   DBGJFK010000129 DBGJFK010000000
VERSION     DBGJFK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3840
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.137"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(444..2831)
                     /locus_tag="ACOIAP_003508"
     CDS             complement(444..2831)
                     /locus_tag="ACOIAP_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGZ2640378.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINDKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDATIEKIIDIIDSTEPGLDIQINSKENASNKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTINISNNFEEDDVINKIKEIINSTEPGLD
                     IQVWSNDKVKERTTEKSGVANDTNKKELISLIIGVLVYIFGIYQTATGYESQFSNIVF
                     IVAYVIIGGDVVLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVKVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFIPPLVIPGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGKFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIKSLKAIGVKEVVMLTGDNEKVAKNIARELELDTVYSNLLPNEKVDRLEELYEGRT
                     EREKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKMIVMILGAGGVATMWEAIFADVGVSLIAVVNAMRAMR"
     gene            complement(2854..3219)
                     /locus_tag="ACOIAP_003509"
     CDS             complement(2854..3219)
                     /locus_tag="ACOIAP_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGZ2640379.1"
                     /translation="MREEINDCNCNIIHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3419..>3840
                     /locus_tag="ACOIAP_003510"
     CDS             3419..>3840
                     /locus_tag="ACOIAP_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640380.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQGELRNDPQISN
                     GYTKVPNNQNINNLYPNNINNYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNS
                     NMGTPNNMSNNMNSNMGIPNNMPNNMNSNMGIPNNMPN"
BASE COUNT         1272 a          691 c          383 g         1494 t
ORIGIN      
        1 aattcgtcaa cactttttta aattattttt ttaaattttt cactttatta tattacataa
       61 tttattgaat ggcagttata ttgttgattt agagtatctt agcacacaca ttttattgta
      121 aaaattataa ctattaatat aatatatatg caatcgtaag tattataatt tttatgagtc
      181 tagtttaaac ttaatataaa tttatcaata aatcctctat atctaaattt taaaattaca
      241 atacaaaagt tatatactaa ataaatgcat taaataaaca taatgaatac aaatttataa
      301 atgaatatag atttatatat acaaaagtac tccaataaaa aggtatcaat aaagttaaaa
      361 gaaacttatt gatacctttc atcattgtat acttcaatat ataattataa gttttttgaa
      421 tagtatagat ttacatttat tccttatctc atagctctca tagcatttac tactgctata
      481 agtgacacac ctacatcagc aaatatagct tcccacatag tggctactcc tccagctcct
      541 aatatcataa ctatcatttt tactcctaaa gcaaatatta tgttttgcca cactatttta
      601 ttagtcttgt tagctatttc aattgcttta gatatcttgc taggctcatc tgtcataagc
      661 actacatctg cagcttcaat agcagcatct gaacctaaac ctcccatagc tataccaaca
      721 tcagcacgag ctaatactgg agcatcattt attccatcac ctacaaatgc tattttttct
      781 ctttcagttc ttccttcata taactcttct aatctatcca ccttttcatt aggaagtaaa
      841 tttgagtaaa ctgtatctaa ttctaattct cgagctatat tttttgctac tttctcatta
      901 tctccagtta acattacaac ttcttttact cctattgctt ttaagctttt tatagcattt
      961 ttactatctt ctttcacttc atcagatata actatataac ctctatatac tttatcaaca
     1021 gcaatataga ctactgtccc tacttctttg gctgatgaat aagatatatt ttcttttttc
     1081 ataagtttct cattacctgc taatataaac ttgccattat gctttactct aattccataa
     1141 gctgctattt cctcatagct gtctattgta tctaaatcaa tttttttatt atagtaactt
     1201 aatatagact ttgctattgg atgatttgaa tttacctccg caatagctgc atattctaat
     1261 aactcttctt ctgatatacc ttcaggattt aacttagtta cattgaacac acctttagta
     1321 agtgttcctg ttttatcaaa tactactgtg tctacacttc ttaaagcttc taaatagtta
     1381 cttcctttaa taaggatacc atttttagat gcaaacccaa ttccactaaa gaaactaagt
     1441 ggtattgata aaactaatgc acaagggcaa gaaacgacta aaaatatcaa tcctctatat
     1501 aaccaatcac taaatacctc acctgggatt acaagtggtg gtataaatgc tattagtaaa
     1561 gcagctatta ctactatcgg agtatagtat ctggaaaact tagatataaa gttttctgtc
     1621 tttgattttt taatgctaga attttcaaca aggtcaagaa tcttagaaac tgttgattct
     1681 ccaaaactct ttgtaacttc aatactcaat aaagcatttt tatttataac acctgataaa
     1741 atttcatctc ctttttcaac ttctctcagc actgactctc ctgtaagtgc agaagtatct
     1801 agcatagaaa ctccatccac tactacacca tctaatggta ctttttcacc aggttttact
     1861 actattatat cgcctacctt tacttcttct ggtgacacca ccttaacttc agaattaact
     1921 tttagatttg cataatctgg tcttatttgc ataagtgaag ttatagattt tctagattta
     1981 ccaactgcaa caccttgtaa atactctcct actttgtaga aaagcataac tcctactgct
     2041 tctgataatt ctcctattgc taatgctcct actgttgcta gagccatcaa aaagttctca
     2101 tcaaatactc ttccttttga tatatttctt attgctctta aaactacatc accacctatt
     2161 atcacatagg caactataaa tactatatta ctaaactgac tttcataacc tgtagccgtt
     2221 tgatatatac caaatatata tacaagaact ccaattataa gtgaaattaa ttctttctta
     2281 tttgtatcat ttgcaactcc tgatttttca gtagttctct cttttacttt gtcattagac
     2341 catacttgta tatcaagtcc tggctctgtt gaatttatta tttcttttat tttgtttata
     2401 acatcatcct cttcaaagtt attgcttata tttattgtaa gttttttatt tacaaagttt
     2461 aaattagaag attcaacttc ttttaattta gaaactttgt tattaatctc ctctgcacaa
     2521 tgtgcacagt ttaatcctcc taatataagc tcttttttaa ttgatgtttt attagatgca
     2581 ttttctttag aatttatttg tatatcaagt cctggctctg ttgaatctat tatatctatt
     2641 atcttttcta tagtagcatc ctcattaaag ctttccttta tatttactgt aagtttttta
     2701 tttataaaat ttaagttgga agatttaacc tcttgtagtt tagaaacttt atcattaatc
     2761 tcttctgcac agtgagcaca atttaatcct cctagtataa attctttttt aattaaatta
     2821 tttgcttcca tatatattca ctcctctcat ttatcattta taagtctctc taatatgatt
     2881 taatccacaa tcaaatatct gacttatatg actatcatct aatgaataat acactgtttt
     2941 tccttctctt ctaaatttta ctaacctagc ctgctttaat actctaagtt gatgagatat
     3001 tgcagagtga gtcatattta ataaactcgc tatatcgcat acacacattt catttgcaaa
     3061 taatgcatat aatatcttta ctctagtagt atccccaaat actttaaata attctgctaa
     3121 atcatataac atctcttcat ctggcatagt tgatttagcc tctgttacta tttcttcatg
     3181 tattatatta caattacaat catttatctc ttctctcatt ttttaatcct ccgttatttt
     3241 aatatatgaa taactgttca tatattcatt atatgctatc atttctaaat ttgcaacaat
     3301 aatttttatt aatttaatac aattagaatg cacatattat aaactttttt aatatatata
     3361 ttattagaat aagtttttgt aaactttttt atagttttct aggaggtgca agtttaatat
     3421 gagtaacaag aaaaaaaagg atttagatac tagttacatg ccttacttag acccagcaaa
     3481 ctatgcagat tatattacaa atgaagaaat tccccaaggt gaattgagaa atgaccctca
     3541 aatttctaat ggttatacaa aagtacctaa taaccagaac ataaataacc tatatcctaa
     3601 taacataaat aattatccta aaagtagtaa ttctccaaac aacttgccta acacaaataa
     3661 tacatctgga aatatgaatt acaatacatc tgctacaaat aatatgccta ataacatgaa
     3721 tagtaatatg ggtacgccta acaatatgtc taataacatg aatagtaata tgggtattcc
     3781 taacaatatg cctaataaca tgaatagtaa tatgggtatt cctaacaata tgcctaataa
//
LOCUS       DBGJFK010000130         3790 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.138, whole genome shotgun sequence.
ACCESSION   DBGJFK010000130 DBGJFK010000000
VERSION     DBGJFK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3790
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.138"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(211..345)
                     /locus_tag="ACOIAP_003511"
     CDS             complement(211..345)
                     /locus_tag="ACOIAP_003511"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640381.1"
                     /translation="MKIVINSYTSRKLTSGDVFMDYLGRFDKVAKEYIKRNKNKGPKK
                     "
     gene            complement(802..1023)
                     /locus_tag="ACOIAP_003512"
     CDS             complement(802..1023)
                     /locus_tag="ACOIAP_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640382.1"
                     /translation="MILKKVIISGICIFTCLLASSIPTFANELQYENIEQYATIEYAN
                     DSMERMSYIKSGSCGLTISNGIATIRSSV"
     gene            complement(1094..1807)
                     /locus_tag="ACOIAP_003513"
     CDS             complement(1094..1807)
                     /locus_tag="ACOIAP_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HGZ2640383.1"
                     /translation="MEILSNKKDNFDITDDMLQEIIPIATKIILDDLPSDDELNHIFS
                     KSFERKMKKLIKQQKRSSLTNKIIFYSKRTAIVFLIVLASLFTITMSSEALRTRLYEL
                     VIRVYEDLTSFVFSTNDGEESLNLKIIEPKYIPNDFKEVDRVDNFIINYKNKNNIEIN
                     YMFCEISSNSIILDTENAKVENISINGNRAKYIEKGTSIQLFWNDKNCIYLLSTDCYK
                     EDLLKKYKNELIKMGKSIK"
     gene            complement(1791..2333)
                     /locus_tag="ACOIAP_003514"
     CDS             complement(1791..2333)
                     /locus_tag="ACOIAP_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2640384.1"
                     /translation="MLIYLAMLELEEDKIKFEKIYEKYRQIMFYVANKILKDDHLSED
                     AVHNAFLRIIKNIDKIDEVDSPRTKAFIVIIVERIAIDFYRKRKREKVSDIEEEYKNR
                     EVNFSIEDKVCESNLTIALAKLNESYFQVLSLKFQYGFSNKEIANVLNLGEENVYKRI
                     QRARKKLKEILEEMEDGNIE"
     gene            complement(2580..2762)
                     /locus_tag="ACOIAP_003515"
     CDS             complement(2580..2762)
                     /locus_tag="ACOIAP_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640385.1"
                     /translation="MKKRFYKVFLKTIPNLIIVILSLALSFYTNTFDIYLKILLLIPL
                     AYVLLFIYYYIKTKKD"
     gene            complement(2790..3401)
                     /locus_tag="ACOIAP_003516"
     CDS             complement(2790..3401)
                     /locus_tag="ACOIAP_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640386.1"
                     /translation="MKNKRINSILSIIMTTVIISLSFVTTANSMEKTESDNNIKIELS
                     DKEVEELHNYWPEDKIFSDEKIDEILIKTGQFTQEELDKINQEVDDYAKKVNQNSRVK
                     YINGYNKYRTFVKNGKKYLYIYVSGKTLKKIKAGADLSSTFGGFLPKIWVGLAVVVIG
                     KIITTNMNGINTNYGIVLSYIEDKWNFQGATYTYRYDHWFYQT"
     gene            3537..3731
                     /locus_tag="ACOIAP_003517"
     CDS             3537..3731
                     /locus_tag="ACOIAP_003517"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HGZ2640387.1"
                     /translation="MQDLCKYTQNLSLKTTNQFLAAFLALVFSNNKVTNKVRQFLDLT
                     LKLIPYALVSTEYSEEKMNL"
BASE COUNT         1325 a          569 c          346 g         1550 t
ORIGIN      
        1 gctttttaag agactgtaag taaatttatg taaaaataaa tttacttaca gtctcgttat
       61 ttattagtat aaatatttac atgaaataac ttaaaacctc aaaatatgtc caccttatac
      121 gctatactta atattaagat ttttatactc tttataaagt actgaaattt atagataaag
      181 ttttaaatta atattaaaga aaataataac ttatttttta ggtcctttgt tcttatttct
      241 tttgatatac tcttttgcta ctttatcaaa tcgcccaaga taatccataa aaacatcacc
      301 agaagttaat tttcttgaag tataagaatt tattactatt ttcatttcaa tcctcccatg
      361 aattttattg atatatagta ttatagcgtg cttctgattg tattcggatt tttttgaaat
      421 ttattaataa cttataagta ctttattcct ttctaaaaat atcaatcaca agtataagta
      481 ttattattat taataataaa ttagcagact ggattaatat aattggccat tcaaaatata
      541 ttatttatag tcacctcatc ttatatgtac aatatatttt tattatcttt ttttactact
      601 tattatattt ttgatttcag agttagcttt taccatagca tgaactctgt aatatccttt
      661 actgattttt tgttttttag aaattgaaca agattatttt cttgaagcat tccatgtatt
      721 aattgtttac catgtctttc tattattatc actcttttgt agtcttacaa ctattgatgt
      781 actttttaca ttcactcttc cctatacaga acttcttatg gttgcaattc cattagaaat
      841 agttaagcca caactaccag attttatata actcattctt tccatagaat catttgcata
      901 ttctatagtt gcatattgtt caatattttc atattgtaat tcattggcaa atgtgggtat
      961 tgaagatgcc aacaaacatg tgaaaataca tataccactt ataattactt ttttcagaat
     1021 cataaaaaac acctcctcat tcttttgtat aactataaaa cgaataaaga gatgctttct
     1081 ggacactaga aaattatttt atactttttc ccatttttat taattcattt ttgtattttt
     1141 tcaaaagatc ttctttatag caatcagtac ttaataagta tatacaattc ttatcattcc
     1201 aaaataactg aatagaagtt cctttttcta tatattttgc tctattacca tttattgata
     1261 tattttcgac cttagcattt tctgtatcta atataataga atttgaactt atttcacaaa
     1321 acatatagtt tatttcaatg ttatttttat tcttataatt aataataaag ttatccaccc
     1381 tatctacttc tttaaaatca tttggaatat atttaggttc tataatctta agatttaaac
     1441 tttcttctcc atcattagtt gaaaaaacaa aagaagtcaa atcttcatat actcttatta
     1501 ccaattcata taaacgtgta cgtaatgctt cgctactcat agtaatagta aataaactag
     1561 ctaaaactat taaaaataca atagctgttc gctttgaata aaaaataatc ttatttgtaa
     1621 gactacttct tttctgctgc ttaatgagct ttttcatctt tcgctcaaaa ctttttgaaa
     1681 aaatatgatt taattcatca tctgaaggaa ggtcatcaag aataattttt gtcgcgattg
     1741 ggataatttc ttgaagcata tcatccgtaa tatcaaaatt atctttttta ttactcaata
     1801 tttccatcct ccatttcttc taatatttct tttaattttt ttctagcacg ctgaatcctt
     1861 ttatatacat tctcctctcc taaatttaat acatttgcta tttctttatt tgaaaaacca
     1921 tactggaatt ttaaagaaag tacttgaaag taactttcat taagttttgc aagagctata
     1981 gttaaattac tttcacatac cttatcttct atagaaaaat ttacctctct atttttatat
     2041 tcttcctcaa tatcagatac cttttccctt tttctctttc tgtaaaagtc tatagcaatc
     2101 ctttctacta ttataacgat aaaagccttc gttcttggac tatctacctc atcaatttta
     2161 tctatatttt taattattct taaaaaagca ttatgtactg catcctctga taaatgatca
     2221 tcctttaata ttttattggc cacataaaac attatttgtc tatacttttc atatatcttt
     2281 tcaaacttta ttttatcttc ttcgagttca agcatagcta aataaattaa catttagaat
     2341 tcctccaata taaaaattct gaattaatat tttaaagttc aattataaca taaatatata
     2401 attaactcta cttaaataga atataattat gcttaacaag ctttttaaat atacctagta
     2461 aaaaggccct tcaaatccat tttggggatt ataagggcct taactttaca actaattctc
     2521 aaagttaaac ttttaaatta attattttcg tatatatcta attccataaa aaataaaaat
     2581 taatcctttt ttgttttgat gtaatagtat ataaacaaaa gtacatatgc taaaggtatt
     2641 aaaagcaata tttttaaata aatatcaaat gtattagtat aaaatgataa tgcaagtgat
     2701 aatatcacaa ttatcaggtt tggaattgtt tttaaaaaaa ccttatagaa tctttttttc
     2761 atattattcc tcctaaaaaa gcatgtcttt taagtttgat agaaccaatg gtcatatcta
     2821 taagtatatg ttgcaccttg gaaattccac ttatcctcta tgtatgataa aacaatccca
     2881 taattagtat ttataccatt catattagtt gttattatct ttcctataac tactacagca
     2941 agacctaccc aaatttttgg caaaaaacct ccaaaagtag atgaaaggtc tgctccagct
     3001 tttattttct ttaaagtctt accacttaca taaatatata aatatttctt accatttttg
     3061 acaaaggttc tgtacttgtt atatccattt atatacttta cacgagaatt ttgattgact
     3121 ttcttagcat aatcatcaac ttcttgatta attttatcca attcttcttg agtaaattga
     3181 ccagttttaa ttaatatttc atcaattttt tcatctgaaa aaattttatc ttcaggccaa
     3241 taattatgca actcctctac ttctttatca gacaactcta tttttatatt attatctgat
     3301 tctgtttttt ccattgaatt tgctgtagta acaaatgata aagatattat cacagttgtc
     3361 attattatgg ataaaatgct attaattctt ttattcttca tttaaatcct cctaactata
     3421 ataaatttat aaaccttgta catatataac gtatctaaac tcgattattg gacaaaaatt
     3481 ttaaaaatat ttatattttt aaaattaaat cttctagaaa ctttaaatgt aaatggatgc
     3541 aagatttatg taagtataca caaaatttat cattaaaaac tactaatcaa tttctagctg
     3601 ctttcttggc attagtattt tctaataata aagtaacaaa taaggttaga caatttttag
     3661 acttaacatt aaaactaata ccttatgccc ttgtatctac agaatatagc gaagaaaaaa
     3721 tgaacttata gatagatttg ataaaaagaa aatacatata aatatataac ttttagtgat
     3781 gtaaaaaaat
//
LOCUS       DBGJFK010000131         3679 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.139, whole genome shotgun sequence.
ACCESSION   DBGJFK010000131 DBGJFK010000000
VERSION     DBGJFK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3679
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.139"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            443..1276
                     /locus_tag="ACOIAP_003518"
     CDS             443..1276
                     /locus_tag="ACOIAP_003518"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGZ2640388.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFVVVGARVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTATEVSKGPSKSSGKVAYITIDDGPSKFTDQIIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIIQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            1345..2301
                     /locus_tag="ACOIAP_003519"
     CDS             1345..2301
                     /locus_tag="ACOIAP_003519"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGZ2640389.1"
                     /translation="MNKKLYIGMVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVL
                     SATNNYINGQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVD
                     SKYQELEDKMNLNTSYKEKMDKAGVDKEYLKQEISRDLAIDKNKKAFEDRINISDNDM
                     EAYYTSHKKDFNVEEISASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESF
                     ESLAKKYSDDKATGKNGGQLGYFSKDDKNAEFTKEVFKLKKNEVSKVFETSYGYHIVK
                     VTDKRERQKSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            2353..2835
                     /locus_tag="ACOIAP_003520"
     CDS             2353..2835
                     /locus_tag="ACOIAP_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2640390.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILIRTSIDFIRKNRKYNNMTDIDLVDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            2847..>3679
                     /locus_tag="ACOIAP_003521"
     CDS             2847..>3679
                     /locus_tag="ACOIAP_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HGZ2640391.1"
                     /translation="MTSKERLNKLKEEYHKIPIPKKLDTIINHEKIENIYQEKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFEERMEKIQSSKNKGHKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKRDSTKFYFIDQKKELPVEDFKTINKYQDFYFNKNEELVICFDEYEVAPGYMGA
                     V"
BASE COUNT         1641 a          325 c          613 g         1100 t
ORIGIN      
        1 atagaatatt gtattatata gaaaatatta cctggttaat atagtgattt atgaggaaga
       61 ttagaaaatt ttacttgata acaaaaatta aacaatatga atatataata tatgtattaa
      121 aaatgtggca aatagttgtt ttagtattta ttctttgttt aatatttcta atttataaaa
      181 aaagaattat aaattttaaa aattataaat aacattttaa ttagaattaa ttgtaaaaaa
      241 cactatataa tactcaattt tcaacattct atacaattat acataaatta tacagcataa
      301 taatcatcaa aataacaaat tttaaaaatt aagcaaaact ttttgtcgaa gttcaacgtc
      361 tatatatatg tagtgtaaat ttttggaata aaatactaca aaaatataaa tgtaaaaata
      421 tagtaatatt ggaggtcgaa cgatgagaaa taaaaagaaa aaaataaata gaaagaagtt
      481 gtatttgctt ttaagtgcta ttgtagtgtg tctggctttt gtagtagttg gtgcacgcgt
      541 tagctcttta aatatgaaag aaaatgaaat tagtagaaat gcaaaactgt caagttctac
      601 tattacagat atagtatcta atacagcaac agaagttagt aaagggccaa gtaaaagttc
      661 tggaaaagta gcatacataa ctatagatga tggtccatct aaatttactg accagattat
      721 aaaaacttta aataaatata atgttaaagc aacttttttt atgatagatg gaaatatgaa
      781 ggaatatcca cagcaagtta aaaatataat taaaaatggg aatacagcag gttttcatag
      841 tgtatcacat gatattcaca agctttatgt tactagtaca tcagcaaaag aagaatttga
      901 tacaaatgat caaacttttt ataagataac tggcaaacat tcaaaagtaa taagaatacc
      961 ttatggaagc aaaccatata caccacaagc ttcttatcag gctttagttg atgctggata
     1021 taaaatttgg gactgggact tagatacaga agactggaga tctaattctt ctcaaattat
     1081 acaaaatgta aaaaatcata ttaagaatag aaaaggtgaa gataaagacc aacttgtagt
     1141 tttaatgcat gagaaaaaac agagtgcaga agctttagat tcagttttaa aatttttatc
     1201 agatgaaggt tatgaatttg ctccagtaga tcaaaatcaa ataccaaaaa attattggtt
     1261 acgtaattta gagtagttaa aatataagaa tattaattga tatttttaga aattgagaat
     1321 aaaaatgagt gaggtgtagg tatattgaat aaaaaacttt atataggaat ggtcggaata
     1381 ttgtctttga tgatggttgg ttgtaataaa agtctagcaa aagtaaatga tgtggaaatt
     1441 acaaaggaac aatacaaaaa aacaaaagca gtcttatctg ctactaataa ttatataaat
     1501 gggcagtctt tagatgaatt agaaaaaact ttggataaaa aaggtagaaa taaattagaa
     1561 aatgttataa tatcgtttat ggtggataat gaacttttat atcaagaggc taaggataaa
     1621 ggactaactc caagtaaaag tgaagtagac tcaaaatatc aagaactaga agataagatg
     1681 aatttgaata caagctataa ggaaaaaatg gacaaagcag gtgttgataa agaatattta
     1741 aaacaagaaa tatcaagaga tttagccata gataaaaata aaaaagcctt tgaagataga
     1801 ataaacataa gtgataatga tatggaagcc tactatacaa gtcataaaaa agattttaat
     1861 gtagaagaaa taagtgcttc tcagatactt atatcgactt tagacaaaaa taaaaaagaa
     1921 gtaagtaaag ataaaaaaga agctttgaag aaaaaggcag ataatatatt gactaaaatc
     1981 aaaaatggag aaagttttga aagtttggct aaaaaatatt cagatgataa agcaactgga
     2041 aaaaatggag gacagctagg atatttttca aaggatgaca aaaatgctga gtttacaaag
     2101 gaagtgttca aattaaagaa aaatgaagtt tcaaaggtgt ttgaaactag ttatggatat
     2161 catatagtca aagttactga taaaagagaa agacaaaaaa gttttaatga gtgtcagagt
     2221 ttaataagag aatctatttt aaatgaaaag tatattgagc atataaaaaa attaaatgaa
     2281 gatgctaaaa tagacagata gaatttctaa cagctcaatc ctggcctgta atcggaggga
     2341 gattttacag gaatgtttaa gagtttaaag agaacgaaag ttgagaaata cattatcgat
     2401 aataaagact ctttttatag aatagcatat agttatacga agaatgagga agatgcctta
     2461 gatgtggttc aagaagctat gtataaggca ctatactcag tggaaaatat taaagaagta
     2521 aattatataa agacatggtt ttataaaatt ttaattagaa cgagtataga ttttattaga
     2581 aaaaaccgta aatataataa tatgacagat attgaccttg tagatgagac tggagagtat
     2641 gataaatata ctgatttgga tttaagaaga gctttagaag aattacctat tgaatacaaa
     2701 tctattataa tattaagatt ttttgaagat ttaaagattg aagaagtagc aataatattg
     2761 gatgaaaatg tgaatactgt taaaactagg ttatatactg ctttaaaaaa actaaaatta
     2821 aaaattgaag agtagggata aaaagaatga caagcaaaga aaggttaaat aagttaaaag
     2881 aggagtatca taaaattcca atacccaaga aactagatac tataataaat catgaaaaaa
     2941 tagaaaatat atatcaagag aaaaataaaa aagtaaatag attaagattt aaagttgcaa
     3001 tagcctttgc atgtatattt acagtattag taaatataag tcctgtattt gcagacaatt
     3061 tttctaaaat acctgtaatt ggagcaatag tagaagtgat aactataaaa aattatagtt
     3121 taaaaagtga aaattatgaa gctgagattg atattcctaa aatacgaggt ttaaaagata
     3181 aaaacttaga acaaagatta aatagtagtt ttatggaaga tggaaaaaga ctttatcatc
     3241 aatttgaaga gagaatggag aaaatacaat catcaaagaa taagggacat aaatctttaa
     3301 gtttgagtta tagtgtaaaa aataattcta aaaaatttct atcaatagag atgacaaaaa
     3361 atgagataga ggcttcatca tatgtgagta aggtacatta tactattgat aaaaaaagac
     3421 aaatagtctt gactttgcca atgcttttta aagatgataa gtatataaaa gttatcagtg
     3481 ataatataaa agaacaaatg agagaacaaa tgaaaaggga tagtacaaaa ttctatttta
     3541 tagatcaaaa aaaagaatta cctgttgaag attttaaaac aattaataaa tatcaggatt
     3601 tttattttaa taaaaatgaa gaacttgtaa tttgttttga cgaatatgaa gtagcacctg
     3661 gttatatggg tgcagttga
//
LOCUS       DBGJFK010000132         3628 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.140, whole genome shotgun sequence.
ACCESSION   DBGJFK010000132 DBGJFK010000000
VERSION     DBGJFK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3628
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.140"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(118..423)
                     /locus_tag="ACOIAP_003522"
     CDS             complement(118..423)
                     /locus_tag="ACOIAP_003522"
                     /inference="COORDINATES: protein motif:HMM:NF012523.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatA-like O-acetyltransferase"
                     /protein_id="HGZ2640392.1"
                     /translation="MNKQKFYKIDLQNWERYTHFYYFSKMTNVGFNLTIEIDITNLLK
                     ETKKRNIKFYPAYLYTITTCLNRYRELKIAYDEDELGYWNTLTPLYAIFHDDNKTFS"
     gene            complement(416..994)
                     /locus_tag="ACOIAP_003523"
     CDS             complement(416..994)
                     /locus_tag="ACOIAP_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2640393.1"
                     /translation="MPTKGEQTKQFIIDTSIMLFSEKGYSNVTMKDICEACNLSRGGL
                     YRHFNSPKEIFISILNTHKHYSQNLLDKGIKENISAKHMLEYFFQQQKADINGKYCGF
                     DFAIHEFAFIEKDQRDYMNKRYSSAITMLSNLIDYGQSKSEFKKCDSKSVAIHIMFLF
                     DSMKTSASILKLTNKDIDNQIKIIKDMVILYE"
     gene            1373..3451
                     /locus_tag="ACOIAP_003524"
     CDS             1373..3451
                     /locus_tag="ACOIAP_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGZ2640394.1"
                     /translation="MRKNKKARKMIIFGFLMCLLIVIIVFLAKFILDGLNKNKPDEVF
                     KQYMSFANKKQYEKMYDLLDEKSKSENKKEDFVLRNKKIYEGIDAHNISIKINDIKKN
                     KNNDKLINYDSKMDTLAGEILFSNEVLLTRDRQKNYKIKWQSSVIFPELEEDNTVRVS
                     KLKGKRGRILDRNGVMIAGQGLASMIGLVPGKMSDNIEDLKKLSTLLNVSVEQIEKKL
                     NASWVKENSMVPIKTIEKIKENPDGTVKEEDKELQESLLSIPGVKISNTEVRVYPFGE
                     KTGHLTGYVQNVNAEILKEKEGKRYNANSIIGKIGLESLLEDRIRGIDGYEIIIADRY
                     GDKKETLVTEPKVDGEDVKLTMDSKLQSKLYDQMKNDKGCAVVMNPKTGEVLSLVSSP
                     SYNPNEFILGMSEDRWNELNKNENKPMYNRFKARLCPGSSFKPVTAGIGITTGKINPN
                     ENFGHSGLSWQKDSSWGSYKVTTLKDYGNTVNMENALIYSDNIYFAKAALKIGEDVLS
                     KELLKLGFDESMPFEFGLSSSKFGTDNKFETEIQLADTGYGQGKLLVNPVHMASIYSA
                     FVNDGDMIKPHLEFKKNLQAEFWKKGVFSKEAVKIIRDDLLQVVESPNGTGHSAMIKG
                     IRIAGKTGTAEIKASKDDVTGTELGWFNAFTVDGNNDKQYLAIAMIEDVKSRGGSHYV
                     MPIVKSVFED"
BASE COUNT         1368 a          409 c          624 g         1227 t
ORIGIN      
        1 ataacttatg taagaaccgt aggaactatg gggatagcct gtggagaatt agtaagacat
       61 attttagtat gcaaaattct atgaagcagg aactctgtga ctttagtcat tggaggttca
      121 ggagaaagtc ttattatcat catgaaaaat cgcataaagt ggcgttaacg tgttccaata
      181 tccaagttca tcttcatcat atgcgatttt tagttctcta tatcgattta agcaagtagt
      241 tattgtgtat aaatacgctg gataaaattt aatatttctt tttttcgttt ccttaagtaa
      301 attagtaata tctatttcta tagtcaaatt aaaccctaca tttgtcattt ttgaaaagta
      361 gtaaaaatgt gtatatcgtt cccagttttg taaatcaatt ttatagaatt tttgtttatt
      421 catataaaat caccatgtcc tttataatct ttatttgatt atcaatgtct ttatttgtaa
      481 gtttcaaaat ggaagcagat gttttcatgc tatcaaataa gaacattatg tgtattgcaa
      541 ctgatttaga atcacatttt ttaaattcac ttttagattg tccataatcg attaaatttg
      601 aaagcattgt gatagctgaa ctgtatcttt tattcatata atcacgttgg tctttttcta
      661 taaaagcaaa ttcgtgtatt gcaaaatcaa atccacagta tttgccattt atgtcagcct
      721 tttgttgttg gaaaaaatat tctagcatat gcttagctga tatattttcc ttgatacctt
      781 tatccaataa attttgagag tagtgtttat gagtatttaa tatactgata aaaatttctt
      841 ttggtgaatt aaagtgtcta tatagaccac cacggcttaa attacatgct tcacatatat
      901 ctttcattgt cacattacta tatccttttt cagaaaatag cattattgat gtatcaatga
      961 taaattgttt agtttgttct ccttttgttg gcatatgttt taacctcctt tttaacgaca
     1021 caagtgtcac ttttaattat gagacatttg tgtcgttttg tcaagttaaa gttatatact
     1081 ataaaataat tacaatacaa taaggttaat ttataaaata gttgaagaat acaaaagaat
     1141 ataatggaac tgatttattt ttaagttgat gtaaaaaata attaaataat aatattatta
     1201 ttgactttta aaacttacat gtgtaatata taaattacta tcaattatac tgcttacata
     1261 tttttatgag atactaaaaa acataataaa aacatagatt agttacgtct ataagattac
     1321 tttaacctta aagcttacgt atgtaatata ttaaatgata aaggtggttt atatgagaaa
     1381 aaataaaaaa gcaagaaaaa tgataatttt tggttttcta atgtgtctac ttatagttat
     1441 tattgttttt ttagcaaaat tcatactaga tggactcaat aaaaacaaac cagatgaagt
     1501 gtttaagcag tatatgtctt ttgcgaataa aaaacaatat gagaaaatgt atgatttatt
     1561 agatgaaaag agcaagtctg aaaataaaaa agaagatttt gttttaagaa ataaaaaaat
     1621 ctatgaagga attgatgcgc acaatataag tattaagatt aatgatatta aaaaaaataa
     1681 aaacaatgat aaattaataa actatgattc taagatggat actttagcag gtgaaatttt
     1741 attctcaaat gaagtactat taactagaga tagacagaaa aattataaaa taaaatggca
     1801 gtcaagcgtc atatttccag aacttgaaga agataacact gtaagggtgt caaagctgaa
     1861 aggtaagaga ggacgtatct tagatagaaa tggtgtgatg attgctggtc aaggtcttgc
     1921 atctatgata ggattagtcc ctggaaaaat gagtgataat atagaagact taaaaaaatt
     1981 atctacctta ctaaatgtat cagttgaaca aattgaaaag aaattaaatg catcttgggt
     2041 aaaagaaaat tcaatggtac ctataaaaac tattgaaaaa ataaaagaaa atccggatgg
     2101 tactgtaaaa gaagaagata aggaactaca agagtcgctt cttagtattc ctggagttaa
     2161 aatatctaat acagaggtta gagtatatcc atttggtgaa aaaactggtc acttaactgg
     2221 ttatgttcaa aatgtaaatg cagagatact aaaggagaaa gaaggtaaga ggtacaatgc
     2281 taatagtata attggtaaga ttggtttaga aagtttactg gaagacagaa tacgtggtat
     2341 tgatggatat gagattatca tagctgatag atatggtgac aagaaagaaa ctttagtaac
     2401 tgagccaaag gtagatggag aagatgtaaa gctaactatg gattcaaaac tacagagtaa
     2461 actatatgac caaatgaaaa atgataaagg ttgtgcagta gttatgaatc ctaaaacagg
     2521 agaggtttta tcacttgtaa gtagtccgtc gtacaatcca aatgagttta tattgggaat
     2581 gtcagaagat agatggaatg aactcaataa aaatgaaaat aaaccaatgt acaatagatt
     2641 taaagcacga ttatgtcctg ggtcttcttt taaaccagtt actgctggta ttggtataac
     2701 aacaggaaag attaatccaa atgaaaattt tggacacagc ggtctaagtt ggcaaaaaga
     2761 ttctagttgg ggaagctata aggtaaccac gttaaaagat tatggaaata ctgtaaatat
     2821 ggaaaatgct ttgatttatt ctgataatat ttattttgct aaggcagcct taaaaatagg
     2881 tgaagatgta ttgtcaaaag agttgttgaa gcttggattt gatgaaagta tgccatttga
     2941 atttgggtta tcctcttcaa aatttggtac tgacaataaa tttgagactg aaatacaatt
     3001 agcagatact ggttatggac agggtaagct tcttgtaaat ccagtacata tggcatcaat
     3061 atattcagcc tttgtaaatg atggagacat gataaaacct catcttgaat ttaaaaagaa
     3121 tttacaggct gaattttgga agaaaggtgt gttttctaaa gaagctgtaa aaattattcg
     3181 tgatgaccta cttcaagttg ttgaaagtcc taatggcaca ggtcatagcg ctatgattaa
     3241 aggaattaga attgctggga aaactggtac agcagaaatt aaagcatcaa aagatgatgt
     3301 tacaggtact gaacttgggt ggtttaatgc ttttactgta gatggaaata atgataaaca
     3361 atatctagca attgctatga ttgaagatgt aaagagtcgt gggggaagtc actatgttat
     3421 gcctattgtt aaatcagtat ttgaagatta aatttactca atttgaaaat taatcttatt
     3481 cagttgagaa taatatttta gataaattgt ttttagactt tttagtaaat tctaaaacaa
     3541 ttaaagaggc tgtttcaaaa tagagatatg cctctttttc attgtttaaa tgataaaaat
     3601 atattttact taatacaaaa aattaaat
//
LOCUS       DBGJFK010000133         3549 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.141, whole genome shotgun sequence.
ACCESSION   DBGJFK010000133 DBGJFK010000000
VERSION     DBGJFK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3549
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.141"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            55..900
                     /locus_tag="ACOIAP_003525"
     CDS             55..900
                     /locus_tag="ACOIAP_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NTF2-like N-terminal transpeptidase
                     domain-containing protein"
                     /protein_id="HGZ2640395.1"
                     /translation="MNITKRMTLLLTLLIVILITGCSPKESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISLENLEDFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSTLYYAQACNYMNFDGFPDYPDATYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQDLNKSLYFNKDNEDPKSNLNTI
                     KKHLK"
     gene            complement(1124..1288)
                     /locus_tag="ACOIAP_003526"
     CDS             complement(1124..1288)
                     /locus_tag="ACOIAP_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640396.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(1820..2011)
                     /locus_tag="ACOIAP_003527"
     CDS             complement(1820..2011)
                     /locus_tag="ACOIAP_003527"
                     /inference="COORDINATES: protein motif:HMM:NF014664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGZ2640397.1"
                     /translation="MRLAISILSRCDEYICYHIEGCVNSGASKDEIIEAIKIGVIGGG
                     SITYPNARFAIKILEEFNI"
     gene            complement(2011..2151)
                     /locus_tag="ACOIAP_003528"
     CDS             complement(2011..2151)
                     /locus_tag="ACOIAP_003528"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640398.1"
                     /translation="MNTREMKEYRGFYNKKLSETNEFFRVFGSLDDKTYSEGAISKKI
                     RN"
     gene            complement(2411..3052)
                     /locus_tag="ACOIAP_003529"
     CDS             complement(2411..3052)
                     /locus_tag="ACOIAP_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HGZ2640399.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVILQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKQNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(3033..3326)
                     /locus_tag="ACOIAP_003530"
     CDS             complement(3033..3326)
                     /locus_tag="ACOIAP_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autorepressor SdpR family transcription factor"
                     /protein_id="HGZ2640400.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
BASE COUNT         1399 a          499 c          329 g         1322 t
ORIGIN      
        1 aatatttgat gctagaatat aattaataaa aatttaatta taggtgattg tattatgaat
       61 attactaaaa gaatgacttt actcttaaca ttattaattg taatattaat aacaggatgt
      121 tccccaaaag aaagtgctag tgaagttgca aaaaaataca ttgataagat gaattctggt
      181 gactatgaaa cagcatatag tttattaagt aaagatagca aaaaaaaaat tagtctagaa
      241 aatcttgaag attttcaaaa tattttagtt agtacaaaaa gaataattag ttataaaata
      301 ggtaaagaaa aaatcataaa aaaatataag catgatggaa aagagtataa aaatgttgtt
      361 aaattagaag aaacttttaa tataaaaaac cttctttata aaaaagatga ttctctaaaa
      421 gtaaatagat attttgtggt tgaaaataat aaatataagc tattattgta tgaaagtttc
      481 aaaaaagaat ttggcattaa tagtatggac cttgctcaac ttaagcttaa tgattttgga
      541 ctaaaatact ttaaagaagt tgacctcata ctaaaaaaag ctattgctat taatcctact
      601 gattcaactc tttattatgc acaagcatgt aattatatga attttgatgg atttcctgat
      661 tatccagatg caacatacaa tgctttagat tcaattaata agtctttaaa gtatttagat
      721 aaaaatgatt ctgactacaa aaaaaatgca agtaatatat ataacttaaa aggagttata
      781 cttatgtttc acaaaagatt tgatgaagca caacaagatt taaataaatc cttatacttt
      841 aataaagata atgaagaccc aaaatctaat ctaaatacaa taaaaaaaca tctaaaatag
      901 atatttaatt tttgaaccta taaaatattt ttttatatat aattcagtac tgaatcataa
      961 tctctactaa actaattaca agtttaaatt ataaagactt atttctatat aaatgttact
     1021 gtataacaat aagtttttta tttaaatttt aaaatattgc ctaaaaatca taaaaaagaa
     1081 ggtataaaga gctaccctca agctcaatat accttataaa tatctaaact tcatttttta
     1141 ctaatttttc tatatctttg ataatatgtt ctttagattt ttttccagct atggcatcaa
     1201 aaattgcaac agcctttttc tctccaaact tttctgctac atcattaaag tctaaaaatc
     1261 taacactttc ttttggttta ccaaacatat aacacctctc atacattttt atatatctat
     1321 tataacttct atagatttat ttttcaccaa taaacgttag acaaattagt ccctttattt
     1381 ttttagacta tctttacctt caaaattcct aacaaaacca gtttattcta ctctataaat
     1441 aaaaatagaa tatttaattt gtagaaaact gataatagaa tacaacaagt aaaactttgt
     1501 ttaatctatc tgcaaaagtc atctgttaaa actgctatga attataaaga gtattctagt
     1561 tcataaaaat acaaatatgc aaatataatt accttaatat tcaatttatt taaaataaaa
     1621 aatatacaaa agatttaata ataacaatat acaattctca atacaatcta tgatgtaaat
     1681 aattcaagac tactatatca ttttaaaatt tatatatgcg attctaaaaa cttaataaga
     1741 aatgaactta gaaaataaaa cttaatttca aatacttaaa tagactatta ttatcctaaa
     1801 taaactactt ctatcaaaat tatatattaa attcttctaa aatttttatt gcaaatcttg
     1861 cgtttggata tgtaatagac ccaccaccaa ttacacctat ttttatagct tctataattt
     1921 catctttact tgctccagaa ttaacacaac cctcaatatg ataacaaata tactcatcac
     1981 atcgacttaa aattgaaata gctagcctca ttaattcctt atttttttac ttatagcccc
     2041 ttctgaataa gtcttatcat caaggcttcc aaatactcta aaaaactcat ttgtttcgct
     2101 taatttttta ttgtaaaatc ccctatattc tttcatttct ctagtattca tcttctacct
     2161 actatgtttt tcttataaga aaatcacact gtgcttatat tttcaacact aaatacaaat
     2221 tttcaattta tgttcattag cctaacttat attatttttt gaaatctcaa caagttatca
     2281 tataagtaag attttttcag aactaaaata gaaatcttag taatttcttt attatctatt
     2341 ctagttctga aatagattat ttttatccaa atattattat agtcattaat tatattagtt
     2401 attttttata ttagttattt ttacctgaaa ttttatacat caaataagaa tatataaatg
     2461 gtagtattac aattacaaag attacaaaga tattataaaa aggaatatta ataaatgcat
     2521 taataattaa taatattcca ccaataagcc aaatccatcc agctaaatgg tgtgtcttat
     2581 tccaattatc ttcatcatta agagtccatg gcaaaattat tcctactgag taattttgtt
     2641 tacatttagg aagatagttt ccaaataaaa taactattat ccctaaaatt aatcccgtat
     2701 aaaaattaga ttccaaacta actcctgttg aatataaaac catcattatt tgtagaatta
     2761 ctgaaagtat agcaactccc cattttgata aattttgtat aacatttgaa aaattagctt
     2821 tcttaggctc attctcaagt ctaaaccatg tatacaaatg gatacatagc attaacaatg
     2881 gtacaccaaa agctgctata acctttggag cataattatc tggatttcca taattatcaa
     2941 aatgaattgc aacttcattt ggtaatctat tataaaaata tattgataca ataaatggta
     3001 taaaacatat taaagtagat aaaataaatt gtttatttat cgcttttttc attatctttt
     3061 tctcccttct ccataaattg tgaaaaccaa agcataacct cttcgaaaac tgaaatattt
     3121 atttcgtaga aaataaagtt cttatacttt gtttcaaata tgagtcctgc tttttttagt
     3181 tgagatagat gataagaaat tgtagcattc gtcatattaa atttttcact aatttctcct
     3241 gctgacattt tattctccct caacataacc aatatttctc ttcttatagg gtctgaaaga
     3301 gctttgaatg tttctggaaa ccccaacacc atcacctcac tatttagaat ttcatctaaa
     3361 tagaatataa cataacatcc attttatttc aataactatt tagaaaaatt tctaaatagt
     3421 tatttctaaa tacttattga aaattttcat attaagattc tcaatttact taagtcgctt
     3481 ttatttaatt cttattttat ctaatttttt aatttaacaa aagtgtactg catcacaatt
     3541 gttaaatca
//
LOCUS       DBGJFK010000134         2799 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.142, whole genome shotgun sequence.
ACCESSION   DBGJFK010000134 DBGJFK010000000
VERSION     DBGJFK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.142"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(27..854)
                     /locus_tag="ACOIAP_003531"
     CDS             complement(27..854)
                     /locus_tag="ACOIAP_003531"
                     /inference="COORDINATES: protein motif:HMM:NF014081.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HGZ2640401.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKEIFKEIPKEY
                     KNLEIIDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPN
                     TLLENTHDSIADTEEIINKYSDTDSIVKPIVTPRFIPSCTSELLKGLGDLCLKYNTPM
                     QSHLSENYDEIEWVRNLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQEEIDLIKK"
     repeat_region   1500..2648
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1500..1528
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaat"
BASE COUNT          965 a          302 c          419 g         1113 t
ORIGIN      
        1 atgactaaag tcacaagtgt gcgtagctat tttttaatca aatctatttc ttcctgagaa
       61 caatgaacac aatgagccat tagagtagga gtttgaccaa ataaattata tctattatat
      121 gcatctccat agaatttaga ttcaggttct agatttctaa cccattcaat ctcatcataa
      181 ttttcagata agtgtgattg cataggagta ttatatttta aacataaatc tcctaaacct
      241 tttaaaagtt cacttgtaca gctgggtata aatctaggtg ttactattgg ttttacaata
      301 gaatctgtat cactatactt atttataatt tcttctgtat cagcaataga atcatgagtg
      361 ttttctaaca aagtattagg gcaattcata ttcatattta ctttaccaac gtatgctcca
      421 agaccaactt ctttgaatat atccataagt ttcatagagg cttctttatg cactgttgca
      481 aacactgcta ttcttgtagt tccagatttc caaagttctt ttacaaattt tttatacatt
      541 ttcgttgcat attcgatatc tttataattt gattcttctg gaaatgtata agtttcaagc
      601 catggtaaaa gctctttatc catagccatt ccaagatttt taaattgaga ggcatgggca
      661 tggaggtcat tcataccagg tattataagt ttatcagtgt aatctattat ttctagattt
      721 ttgtattcct taggtatttc tttaaatatt tcttttactt tgcctttttc tagtataata
      781 tagctatttt caaatactgt gaaagtttct gaagtttttg tgaaaattat atttcctttt
      841 agtactttta acatataggt ctccttagtt ttaaatttat tttaatatat gtaggttata
      901 ttttgggtta caaatcaaaa ttttaccaca tgtattatat caaatctaaa ctataaatac
      961 tattggataa tagcaaatat tagtgaaata cagttgttta ctattattat ataactaaca
     1021 tctaagtgac atttaagaaa aatatgagat tactgatatt ttactgatat aaaactgaat
     1081 gttatttaaa gagagccttg attatatttt tagaagcttt ttatgcatat tatctaaaat
     1141 atgagaatat ctattcatag ttatttttat atcagtatga cctaattttt tagagagaat
     1201 ttttatatta aatccagtta gaagaagact tattagaata tccaatgtag taagcactag
     1261 cagatattct taaattgata aattactcca ttttaatttt ataggttaaa ttttatgata
     1321 taataaaaat atataaattt tgcagtgagc gatatttttg ataaagtagg gtttaacagt
     1381 tgcaatgtaa ggcgttgagg gtgtatgata aatgttatca attgcactac tcatggttca
     1441 ctgcaaattt aagaaagttg tatgtgtgta agtactgaaa atacttagtt tattttgggg
     1501 ttttatatta actatgtggt atgtaaatct tgtagataat gcagaagaag aagaaaaaca
     1561 gattgtttta tattaactat gtggtatgta aatgatgcta ccttattttt atctaatccc
     1621 caaataaact gttttatatt aactatgtgg tatgtaaatt tatttcttaa ccagtcaaat
     1681 aatctatttt gtcctggttt tatattaact atgtggtatg taaatatcat agtttattaa
     1741 cacaggaaac gaggttagtt cgttttatat taactatgtg gtatgtaaat aactctttta
     1801 aaaaagaata tacgattttc agagaaggtt ttatattaac tatgtggtat gtaaattatt
     1861 aattgcttat ctattaattc ttttaatttt tcagttttat attaactatg tggtatgtaa
     1921 attgaagggt tataaaaaaa ataatagcga aaagggcggt tttatattaa ctatgtggta
     1981 tgtaaatcac gaaaaaatca gaaggggagg ggggttattt aaaagtttta tattaactat
     2041 gtggtatgta aatttaaaac ttgaattatt tcaaaaagct aaacatcaag gttttatatt
     2101 aactatgtgg tatgtaaatt ttaattgccc ttcatagaat attatttcac cttcttgttt
     2161 tatattaact atgtggtatg taaattatga gaaagttgaa tttaaaggcg aaatgaacat
     2221 gggttttata ttaactatgt ggtatgtaaa ttctttatat tgatatccaa gaataagcgc
     2281 acgttcttgt tttatattaa ctatgtggta tgtaaatttg cttagcgcaa taacttttga
     2341 aaatactaca ggagtgtttt atattaacta tgtggtatgt aaattaagat gtccaaatgc
     2401 taagagagaa ttcttaggat agttttatat taactatgtg gtatgtaaat aaaagaagtt
     2461 ttgaaagtaa atgtgtaaat aataatagtt ttatattaac tatgtggtat gtaaatgaag
     2521 tcaacaattt ggctattggt taagtacaac tagcgtttta tattaactat gtggtatgta
     2581 aataaagaaa attgggtttt tgattaagaa cttgcgaatg ttttatatta actatgtggt
     2641 atgtaaattt gcaacaagta taggtaaaat actccaataa tttatatagc attttctcct
     2701 ttaaaatata attatttttt atcatttgta gtaagtaatt accagataac attgacttta
     2761 gtcttattga ttaaaatata aaagtagaat aattataaa
//
LOCUS       DBGJFK010000135         2607 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.143, whole genome shotgun sequence.
ACCESSION   DBGJFK010000135 DBGJFK010000000
VERSION     DBGJFK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2607
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.143"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            292..>2607
                     /locus_tag="ACOIAP_003532"
     CDS             292..>2607
                     /locus_tag="ACOIAP_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
                     /protein_id="HGZ2640402.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTGKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSGGSSSSKVGQIKFNATDKQIKMASGDKTVDPSDNTYVLKLTNGTVKDGDVK
                     ANVEVTGLPSGLDYTAVGNKSANTITITVSGTASQALQADLDNVSVLVKAGAVSETTA
                     TDSIANATFEVKKYVAAPAVGQLTFDATDKQIKMASGDKTVDPSDNTYVLKLTKGTVK
                     DGDVKANVEVTGLPSGLDYTALGDSSSNTITITVSGTASQALQADLDNVSVLVKAGAV
                     SETTATDSVANATFEVKKYVAAPAVGQLTFDA"
BASE COUNT         1112 a          341 c          485 g          669 t
ORIGIN      
        1 ttaattctaa aggctacttt tttatgtgaa accctacttt ttacaacaat tcattaacat
       61 aaaaatcaaa cttaccttaa aatataaatt tacaaatttt tcaatcaata aaaaaatttc
      121 tttattcctt atataatgac tgcaatgtat caaaataatt acaaattaat tatgaaatca
      181 ttatagttag aaacctcttt aaaattagat attaagtatc ctttagaatt agaacgggaa
      241 caaagttaaa aaattaagta atatcaaatg gacaaggggg aagaaaatac aatgaaaata
      301 ccaaagaaga ttgctgcaat gcttacagta acaatgatag ctggaagttc aacagcaggc
      361 atagctagtg cacaaactgt ggcaacaaat ttaacagggc aagaaagata tgaaactgct
      421 gttaaaataa gtcaagatgg atggaaaaat gctgatgagg tagtaatagt aaacgactca
      481 tctatagcag atgctctatc tgcaacacca tttgcaaagg caaaaaatgc tccaatactt
      541 ttaacaggta aagataaatt aaatgataag acgaaagcag aaatacaaag attaaaagct
      601 aaaaaagtat acttaatagg tggaacttct gtattaagca caaacataga aaaagaaata
      661 aaagatttaa aaatatcttt tgaaagaatc tctggagctg agagatatca aacatcctta
      721 gaattggcaa agaaattaga tgctataagt gatgttaaga aaatagctgt agttaatggt
      781 gaaaaaggac ttgcagatgc tgtaagtgta ggagcaccag ctgcacaaaa caatatgcca
      841 gtaatacttg ctgattctaa aaatggaaca gcagttgcag acaaatttat aaaagatgct
      901 ggaataactc aatcttatgt agtaggtgga gagagttcaa tttctgaagc tgttaaaaat
      961 aaactaccaa atagtacaag actaggcgga acagatagaa atgatacaaa tgcaaaagta
     1021 ataaaagaat tttataaaaa gacagattta aaaaatgctt atgtaactaa agatggaatg
     1081 aataaacaag accaacttat agatgcacta gcagtaggtg tattaggtgc taaaaatcaa
     1141 tcaccagtag ttttagttgg aaagaactta tcagcttcac aaaaatctct agttaactct
     1201 aagagttttg ataagataac taaagttggt ggaaatggta atgagacagc atttaatgaa
     1261 atgaaatcac tacaagaagt aaaaacagtt gaagctaaaa caatttctga attaaaatca
     1321 gctatagata aagctactgc taatgatgtt ataaacttta agccaactag tgaggttaaa
     1381 gaagcattta caatacaaac tgataaagca gtaacagtaa acttaaatgg tacatataca
     1441 aagactgtga ctatcaacat gcctaatggt gatgtaaata actatgcaaa agtggatgat
     1501 gtagttatag atgatgtaaa agatggaact tttgttaact atggaaagat aaccaactta
     1561 aaggttaatg ataaaaatgg agctaagata gagaataatt ctaaaggtga gattggtagt
     1621 ttaacagtag catctggagc aagtcaagta aaagtgacta atggtggaaa gataactaca
     1681 gttacaaata attctaaagg gactactata gataataaag gtacaataag tagtgttaag
     1741 ggagataatt ctccaacaat aagtggaaat agtccaagtt ctaactcttc aggaggaagt
     1801 tcatcaagtg gaggttcttc acatggagga ggtagtggag gaagttcttc atcaaaggta
     1861 ggtcaaataa aatttaatgc aacagataaa caaataaaaa tggcatcagg tgataagaca
     1921 gtagatccat cagataacac atatgtacta aaattaacaa atgggacagt aaaagatgga
     1981 gatgtaaaag ctaatgttga agtaacagga ttaccatcag gattggatta tacagcagta
     2041 ggaaataaat cagcaaacac aataacaata acagtatcag gaacagcaag ccaagcatta
     2101 caagctgatt tagataatgt aagtgtgtta gttaaagcag gagcagtatc tgaaacaact
     2161 gctacagatt caattgcaaa tgcaacattt gaagtaaaaa aatatgtggc agcaccagca
     2221 gtaggtcaat taacttttga tgcaacagat aaacaaataa aaatggcatc aggtgataag
     2281 acagtagatc catcagataa cacatatgta ctaaaattaa caaaaggaac agtaaaagat
     2341 ggagatgtaa aagctaatgt tgaagtaaca ggattaccat caggattgga ttatacagca
     2401 ttaggagatt catcatcaaa tacaataaca ataacagtgt caggaacagc aagccaagca
     2461 ttacaagctg atttagataa tgtaagtgtg ttagttaaag caggagcggt atctgaaaca
     2521 actgctacag attcagtagc aaatgcaaca tttgaagtaa aaaaatatgt ggcagcacca
     2581 gcagtaggtc aattaacttt tgatgca
//
LOCUS       DBGJFK010000136         2533 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.144, whole genome shotgun sequence.
ACCESSION   DBGJFK010000136 DBGJFK010000000
VERSION     DBGJFK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.144"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            179..739
                     /locus_tag="ACOIAP_003533"
     CDS             179..739
                     /locus_tag="ACOIAP_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGZ2640403.1"
                     /translation="MTNILKFKLLSFSKEKKEHSLEKKAIYGDKKAFENLIENNEEYL
                     YKMAFLYTKNEHDALDIFQDTVYKAFLNIDKLKEPSYFKTWITKILINTFNTKYKKTV
                     NYLNIRDYEHKIEEVNYQQIEDKIDLYDAIDRLDEKYKTPIILQYFQDMTIGEIAEIL
                     DINENTIKTYLRRGKASLYELLKEEK"
     gene            741..1775
                     /locus_tag="ACOIAP_003534"
     CDS             741..1775
                     /locus_tag="ACOIAP_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4179 domain-containing protein"
                     /protein_id="HGZ2640404.1"
                     /translation="MSKYDDIKIPESLKRVRNSAIEKAYKDKKFKRDKKRFTMTVSIA
                     IIGLGLLGIGVSNPTFAQKILRVNEMIQAIQGIFTNNELSDSITTIGESSTRDGLTIT
                     VQNAYYSQNEITLEIELKTDKPFKNTKYSKVIVKDNKDESIDDFALMTKDFNTWINGE
                     ETKGIVYESPRFKYIDEYTLKGYWQINFKSPIENHKNYDTIKMSFGLNETNYDKKSNN
                     YKYTNSINGPWILEFPVKSNMDKVKIIKPDIRQDIITVKQVALSQTSLNLKLELEKQG
                     VIEYVEVKDDNGETLGGGMESSNPNKIDLDFGLKNVNQSPKYITIFAYGNIDNGKDES
                     KAIKIKINLE"
BASE COUNT         1087 a          252 c          331 g          863 t
ORIGIN      
        1 ataaaaactt atatataaat aatgcaaata ttaaaaagta aataaatgtt ggaaagatta
       61 tgtttctata agctagtttc taaagagtta ttctgaaatt agttataaaa tttatatttt
      121 tgaaacttta tatacaaaat aatagtctaa ctaatgtgac aatataaagg aggctgagat
      181 gactaatata ttaaaattta aattattatc cttttctaaa gaaaaaaaag aacatagcct
      241 agaaaaaaaa gctatttatg gagataaaaa agcatttgaa aatttaatag aaaataatga
      301 agaatattta tataaaatgg catttttata cactaaaaat gaacacgatg cacttgatat
      361 atttcaagat acagtatata aagcattttt aaatatagac aagttaaaag aacctagtta
      421 ttttaaaaca tggataacta aaatattaat aaatacattc aatacaaaat ataaaaaaac
      481 agttaattat ttaaatatta gggattatga acataagatt gaagaggtaa attatcaaca
      541 aattgaagat aaaatcgatt tatacgatgc aattgatagg ttagatgaaa aatacaaaac
      601 acctataata cttcaatatt ttcaagacat gacaattggt gaaatcgcag agatacttga
      661 tattaatgaa aatacgataa aaacgtactt aaggcgaggt aaagcaagtc tttatgaact
      721 attaaaggag gaaaagtgat atgagtaaat acgatgatat aaaaatacct gaaagtctta
      781 agagagtaag aaattcagca atagaaaaag catataaaga taaaaagttt aaaagagata
      841 aaaaaagatt tactatgact gtaagtattg caattattgg attaggattg cttggaatag
      901 gtgtatcaaa tccgacattt gctcaaaaaa tactgagagt aaatgaaatg attcaagcaa
      961 ttcaaggtat atttactaat aatgaactgt cagatagtat tacaactatt ggagaatcaa
     1021 gtacaagaga tggacttact ataactgtcc aaaatgcata ttatagtcaa aatgaaatta
     1081 ccttagaaat agaactaaaa acagataaac catttaaaaa cactaaatat tctaaagtca
     1141 tagtaaaaga caataaagat gaaagcatag atgattttgc tcttatgact aaggatttta
     1201 atacctggat aaatggagag gaaactaaag gcattgtata tgaatcacct aggtttaaat
     1261 atatagatga atatactctg aaaggatact ggcaaataaa ttttaaatcg ccaattgaaa
     1321 atcataaaaa ttatgatact atcaagatgt cttttgggct taatgaaaca aattatgata
     1381 aaaaatcaaa taattataaa tatacaaatt ctataaatgg accttggata ttagaattcc
     1441 ctgtaaaatc aaatatggat aaggttaaaa taataaaacc agatattaga caagatatca
     1501 taactgttaa gcaggtagct ttaagtcaaa catcattaaa cttaaagtta gaattagaaa
     1561 aacaaggagt tatagaatat gtagaagtta aagatgataa tggagaaact ttaggtggtg
     1621 gaatggagag ttctaacccc aataaaatag acttagattt tggattaaaa aatgtaaatc
     1681 aatctccaaa atatataaca atatttgcct atggcaatat tgataatggc aaggatgaaa
     1741 gtaaagctat aaaaattaaa attaatttag aataatcaat tatcccttaa aagttattta
     1801 gaaatttact aattatagat aaagttaatg cccttgaaat ccaaataaat agattttaag
     1861 ggcattttta ttatatattt tcttttatat tactaaaagt tacatattta tatgtatttt
     1921 atttttatca aatctatcta taagtttatc ttttcttcgc tgtatcctgt agatacaaag
     1981 gcataataca ctagtttcaa atatttcccc caattttcta aatattttca ctttttcgtt
     2041 ttattactat gaagtctatg atataatttt aaaaagagat actttccaat aaaaaagtta
     2101 ttttaaacct attattaaaa ttttgaaagt tgttgatgat tatgaataaa aaaaatatat
     2161 tcaacgatat gtttcttatt gtttatccaa ttataatatt aatttctatg ttctttaact
     2221 cattattaca tgagcagata ctaagattta atattaataa acttcaattt atggttttta
     2281 tattagttta tttttttata tttgcattgt ttatatataa gttttttata aaaaaagaga
     2341 gttttcatat agtctctttg attataggta tgtttttgat aataatcata caaatcccac
     2401 aagttttatt aacgatttta cacaatttat tcagtattgt ttatggacaa tttcaattag
     2461 atatatttat gtttggaaca cttttgactt tatatacaat aattattatt atgtattata
     2521 aagaaaatca taa
//
LOCUS       DBGJFK010000137         2396 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.145, whole genome shotgun sequence.
ACCESSION   DBGJFK010000137 DBGJFK010000000
VERSION     DBGJFK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.145"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(120..1412)
                     /gene="brnQ"
                     /locus_tag="ACOIAP_003535"
     CDS             complement(120..1412)
                     /gene="brnQ"
                     /locus_tag="ACOIAP_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGZ2640405.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFARAGKGLSVALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     DKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     VPLVNNLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          805 a          376 c          254 g          961 t
ORIGIN      
        1 tattaaatag gattaataat agtcttttat ctacaataat ttaataattc ttttaaatat
       61 aaaaggaatt gcctatataa tttaaaggca attccataat tatcaattag tttttataat
      121 tatgcagttt tgctactttt agatggaata aagtttccta ttattcctgc tattacaact
      181 ggaactatcc agttaaatcc taatgaagca aatggtaagt tattaactag aggaactttc
      241 acaccaaaac ttgttgcaac tgttaataca cttactaata atgccatata tgcagcacat
      301 ttgaacacgt tatcattttt aattttatta ctaaataatg ctagtataac tagagttata
      361 gttgctggat ataccatact tagtatagga gaagagaatt gtattattgt acttactcca
      421 aagtttgata ttattgcact aaatacacaa actactataa ctatatgctc atattttaat
      481 tttccatctg taagtgttga gaaatattga ccagctgctg aagaaagacc tatagctgtt
      541 gttaaacatg ctaatgcaac tataatagct aataaaattt tacctgtagt tccaagtaaa
      601 gctgctgtta ttgcaactat taaagctgtt tgttgaacat cttgtccata ttgttgagac
      661 acagttgctc caagataaca taatccacca taaactagtg ccattcctat tactgcaatc
      721 acacctgcac ttattgtggc tttcatcttt tctttatcac ctgtataacc tttagctatt
      781 actgacatga ttataattga tgcaaataca ctagctgcca atgcatccat tgtttgataa
      841 ccttgagtta taccttctgc aaatacattt tgtattaaag aactgtctct tatttctcct
      901 aatggagata cgataccttt aactattaat actgctaaag ctataagtaa agctggagtt
      961 aatattgacc caactatatc tacaactttt gatggtctta ttgttaaaac caatactaaa
     1021 gcaaagaaca ctatagagaa tatcactgga cttattccag aacctattgt aggtaatata
     1081 cccatttcat aagttgttgc tgctgttcta ggtattgcta aaagtggccc tatacagatt
     1141 accattgcac atcctaatgc aacacttaat cctttgcctg ctctggcgaa catctttgat
     1201 gtgtctccat tgaacttagt tgctgctata actgctaata atgccaaacc accatctgca
     1261 aaaaggaatc ctatgaaagc tactagccag ctacttccag ataaaactcc taaatatgga
     1321 gggaagatta agttccctgc accaaaaaac attgcaaata gtgcaaatcc aattacaatt
     1381 acatctttaa aattgatttg tttctcaccc atttaaagca cccccatttg aattttacta
     1441 cattttacta aaaaataagt ccaatctctt cttaaatgaa aaccttttga cgagatttta
     1501 tttaattata catttttgac ttaaatttgt caattatgtt tcataattta taaaatcttc
     1561 acaatattta atacaacttt cttaattaaa caaaatcaac gtgtatactt taaacatagt
     1621 tggttttttg ttttttatct aatttttctt gataaaatta attattctga ataattaaaa
     1681 tattaggatt ttttagatta ttcgttttat tattaagttg tattgcttta tgtattatat
     1741 atcactctcc tttttacata catataatct ttttaattca atttaaattt taaatatttt
     1801 gtgtttatta tataatctga aaaaaaagca gtcaatagca tttttaattt tttaaatttt
     1861 caaaattatg atttttgaaa aatcgttttc cttttatcat agcacctatt tacgttaatt
     1921 cttgtagtat tttgtattta ttttgctaaa tttatagtta actttattta atttctattc
     1981 tacttatata gattcacctc ttgcttttta gttttgaaat cgttttttct gaaaattcct
     2041 tattatgatt tatcaactta tttttcttca tagtaattat tttctaactt ccaacttact
     2101 taaactttgc agttgctagt attcacgttt acatacttat ctgtcataat taactaaaaa
     2161 ttcttaatat atctctcagt aaaaacaatt caatcattta cttaatacat ttatataatc
     2221 atatgtctta aattttgttt tattatttta ttattgtcac aattttattt atattatatt
     2281 tttgtaaaaa tcatttaata tatatactta aatttataaa attactctaa aattcttttt
     2341 taatctctat cgttgttaaa aaataaacta tatatttttt tgatattttc ttatac
//
LOCUS       DBGJFK010000138         2289 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.146, whole genome shotgun sequence.
ACCESSION   DBGJFK010000138 DBGJFK010000000
VERSION     DBGJFK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.146"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..927
                     /locus_tag="ACOIAP_003536"
     CDS             <1..927
                     /locus_tag="ACOIAP_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HGZ2640406.1"
                     /translation="FSKRFNYYIWLVMVFRMLLFLFNYTVIYEVKEPKENTVGNNITQ
                     IDISTDNNLVLYLAYLWLFVTIVIAVYTFIKYTRFKNLVVDVSYSIEDNDVNCIYKNL
                     LKELNIKKKIELRGSDELISPAGMGLFKSYIFLPDYPYSRDELSWILKHELMHFKNKD
                     ILIKFLVLSVKIIYWFNPLVYIMSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKS
                     IKLSRNYNSGILTTEFNKTSLEKRLDSIVKKKGKSGILVLLILFTLFSVTYFNFESIS
                     FDNSNSLRNIGILEKSGADLKEENDISMRIVN"
     gene            993..1580
                     /locus_tag="ACOIAP_003537"
     CDS             993..1580
                     /locus_tag="ACOIAP_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="HGZ2640407.1"
                     /translation="MKNLKKILIVTGCLTLISTSLVFANTTTDVDTSKDDDSVISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKDDIIFVNKDSIDVNDIENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLDVSDTVVGYNRVESGNPVHLVQLLCRTLDGSSIKDDSEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(1796..1993)
                     /locus_tag="ACOIAP_003538"
     CDS             complement(1796..1993)
                     /locus_tag="ACOIAP_003538"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640408.1"
                     /translation="MESYNRLLKKVTKSKSIFPSDDSLHKSLYLATMDIFEKRSHKIR
                     NWTQVLAHLSIYFKERNLTLN"
BASE COUNT          838 a          218 c          357 g          876 t
ORIGIN      
        1 tttagtaaga gattcaatta ttatatttgg ttagtaatgg tctttagaat gttacttttt
       61 ctatttaatt atacagtaat atatgaagta aaagaaccca aagaaaatac agtaggaaat
      121 aatattacac aaattgatat ttctacagat aataatcttg tgctgtattt agcttattta
      181 tggttatttg taactatagt cattgcagtt tatacattta taaagtatac aagatttaaa
      241 aatcttgttg ttgatgtatc ttatagtatt gaagataatg atgtaaactg tatctacaaa
      301 aacttgttga aagaattaaa tataaaaaag aaaattgagt taagaggttc tgatgaattg
      361 ataagtccag caggcatggg attatttaaa tcttacatat tcttaccaga ctatccttat
      421 agtagagatg aactaagttg gattttgaag catgaattaa tgcattttaa aaataaagat
      481 attttaataa agtttttggt tttgtctgtt aaaataatat attggtttaa tccacttgtt
      541 tatataatga gcaataaagt aaatctagat tgtgaattat gttgtgatga aagtgttttg
      601 actgattgtt ctttaaaaga taagaaagaa tatgcattag cacttataaa gtcaattaaa
      661 cttagtagga attataatag tggtatttta acaacagagt ttaataagac aagtttagaa
      721 aagagacttg acagtattgt taagaaaaaa ggtaaaagtg gaatattggt gttattgatt
      781 ttgtttacat tattttcagt tacatatttt aattttgaaa gtattagttt tgataattca
      841 aactctttaa ggaatatagg tattttagaa aaatcaggag ccgatcttaa ggaagaaaat
      901 gatattagca tgagaattgt aaattaatag attaatatat gtaatgaaaa ggtatattgt
      961 catattatta ataaattagg aggaattatg aaatgaaaaa tttaaaaaaa attttaatag
     1021 ttacaggctg tctaacttta atatctacta gtttggtatt tgcaaatact actactgatg
     1081 tagatacatc aaaggatgat gattcagtaa taagttcatg tactataact ggttatgaat
     1141 ttacttatga aaacgcacca caatctgtaa aatttgatta tgaaaaaaaa tgtgaagcgc
     1201 taaatataaa accatctaaa gatgatataa tttttgttaa taaagattct atagatgtaa
     1261 atgatataga aaactatgtt gagccaaaag catatattat tagatataaa aaaggttatg
     1321 tttttgaagt tactggacct aagagttata cactagatgt aagtgatact gtagtaggat
     1381 ataatcgtgt tgaatcaggt aatcctgtgc atttagtcca acttttatgt agaactttag
     1441 atggttcaag tattaaggat gatagtgaat ttggacctgc tacatataat gcagttaagt
     1501 cacttcaagg aagacttgga ttaacaagag atggaattgt tggaagaagt acttgggatg
     1561 cagctggaag acgtctttaa aaaagagagc tattgcacag ataattttaa attgttaaat
     1621 ctgtaaacat ttatgtgtat tctttaaata aaaatttgtt ttttaagtga taattaaatt
     1681 tttactgata gggctatggc tttaaaaatc atagccttat ttcgatgttt tttcgttttt
     1741 gtaaaattat tgccatttta agaaaattta ttgatttttt tgaaatattt ctttattaat
     1801 ttagagttaa atttctttct ttaaaataaa tacttaaatg agctaaaact tgagtccaat
     1861 ttctaatttt atgagaccgt ttttcaaaaa tatccatagt tgctaagtat agtgatttgt
     1921 gcaaagaatc atctgaagga aaaatagact tcgatttagt aacttttttt aataatctat
     1981 tgtaactttc cattgagttt gtagtatata tcaatgttct tatccatgag gatatttaaa
     2041 atatgttgcg aactcattcc aattgcttcg ccaatttctt aatgctacct cttctgtaat
     2101 tgcatcatat actttcttta atgagttttt ttacatttcg tttttgttaa acataaaaag
     2161 tgagcgcctt cctttgtata gtgatatttg atattttaat tattattact ttttagaata
     2221 atacacactt tattttaaag accctgaaaa tgatattttt atacattata tttgttatgc
     2281 ataatttta
//
LOCUS       DBGJFK010000139         2274 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.147, whole genome shotgun sequence.
ACCESSION   DBGJFK010000139 DBGJFK010000000
VERSION     DBGJFK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2274
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.147"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            178..825
                     /locus_tag="ACOIAP_003539"
     CDS             178..825
                     /locus_tag="ACOIAP_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640409.1"
                     /translation="MNILIADDEISMLKILCAYFKKENFNVLTAKNGEEALDIFYKNK
                     IDLAILDWMMPIIDGIEVCKEIKENSNTKVLMLTAKSQSEDEIEALNIGADEYIKKPF
                     DPRVLIIRAKKLVNYKDTINIKDLKIDFESSKVFKGDNELLLTKKELELIRCLINNKG
                     MILSREKLLDLVWGLDYEGDFRTVDTHIRRLRVKIGEDIIKTYRGLGYSLEDFND"
     gene            818..2212
                     /locus_tag="ACOIAP_003540"
     CDS             818..2212
                     /locus_tag="ACOIAP_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2640410.1"
                     /translation="MTKLNKKLSISISIVVVVVYIVSITINSMFIHRYYLHEKRNILD
                     NIENEIKDKDIDKLKSDIDSIEEKNNADIVYIELDKNHKDKGNIDRINQDLLNAFWKK
                     GLSLNKFWIEENSLKNIGKKSINKIYNQGKTKYSLLVKFIKKDNYLFAISIPIEHSEE
                     TIGIVNRFNIIMGVFSVVIITILTFILSNRVIKPIEKLKFLSKDISELNFRIEDIKTN
                     DEIEELAYSINMMSEKLEKAHNELNKRNENLKTFISDASHEIKTPIALIKAYAIGMKD
                     GLDDGTYTDTIIEQAENMTNTINSLLYWAKYEKKERSLCLVDLKERLYKSLKNYELLI
                     DKGGISVKCNVDDRELIISSDEDSIEVVFNNLISNAIKYTNNNEIEINLFEENERIIL
                     SIKNGIDCDMEDEIENIWKPFYVLEKSRSKELSGTGLGLTIVRTILEENNFRYRVEIC
                     DKIIAFYIIFIKLI"
BASE COUNT          985 a          158 c          394 g          737 t
ORIGIN      
        1 aaatattata atatattagt tacatattaa aatatataat caagatattg tcgaggtatt
       61 ataatatata actaatgtat tataaatagt tgtaaacttc ctgtaacata tattttatat
      121 aattaaagta atggatataa tattaaatat aataatgaat tttagggatg tgaataaatg
      181 aacatattaa ttgctgatga tgaaattagt atgcttaaga tactttgtgc atattttaaa
      241 aaggaaaatt tcaatgtact tactgcaaaa aatggggaag aggctttaga tattttttat
      301 aaaaataaga tagacttagc aatattagat tggatgatgc caataattga tggaatagag
      361 gtttgtaaag agataaagga aaatagtaat acaaaggtac ttatgttgac tgccaaaagt
      421 caaagtgaag atgaaataga agcactcaat attggtgcag atgaatatat taaaaaacca
      481 tttgacccta gggttttaat aataagagct aagaaactag taaactataa agatacaatt
      541 aatattaaag atttaaaaat agattttgag tcaagtaaag tttttaaagg tgataatgaa
      601 ctattattga ctaagaaaga attagaatta attcgttgtt taataaataa taaggggatg
      661 attttatcta gagaaaaact tttagattta gtatggggtt tagattatga gggtgatttt
      721 agaacagtag atactcatat aagaagatta agagtaaaaa taggagagga tataataaaa
      781 acttatagag gattagggta tagtctggag gattttaatg actaaactga ataaaaaatt
      841 gtccataagt atatcgatag tagtcgtagt tgtttatata gtgtctataa ctataaatag
      901 tatgtttatt catagatatt atttacatga gaaaagaaat atattggata atattgaaaa
      961 tgaaattaaa gataaagata tagataaatt aaaatcagac attgattcaa ttgaagaaaa
     1021 aaataatgca gatattgtat atatagaatt agataaaaat cataaagata aaggtaatat
     1081 agatagaata aatcaagatt tattaaatgc attttggaag aaggggttaa gtttaaataa
     1141 gttttggatt gaagaaaata gtttaaaaaa tattgggaag aaaagtataa ataagatata
     1201 caatcaaggt aaaacaaaat atagtttact tgtaaaattt attaaaaagg acaattattt
     1261 gtttgctata tctataccca tagaacattc tgaagaaact attggcattg taaatagatt
     1321 taatataata atgggagttt tttcagtagt tataataact atacttacgt ttatattatc
     1381 aaacagagtc ataaaaccta tagaaaagtt aaagttttta tctaaagata tatctgaatt
     1441 aaattttagg attgaagata taaaaacgaa tgatgaaata gaggagttag cttacagcat
     1501 aaacatgatg agcgaaaagc ttgaaaaagc acataatgaa ttgaataaaa gaaatgagaa
     1561 tctaaaaact tttatatcag atgcatctca tgaaataaaa actccaatag cacttataaa
     1621 agcatatgca ataggtatga aagatggctt ggatgatggg acttatacag atacaattat
     1681 tgaacaagca gagaatatga ccaatacaat aaattctctt ttatattggg caaaatatga
     1741 gaagaaggag agaagtctgt gtctggtaga tttaaaggaa agattatata aaagcttaaa
     1801 aaactatgag ctgttgatag ataaaggtgg gataagtgtt aagtgcaatg tagatgatag
     1861 agaacttata ataagttcgg atgaagatag tatagaggtg gtatttaata atttaattag
     1921 taatgctata aagtatacta ataataatga aatagagatt aatctttttg aagagaatga
     1981 gagaattata ttatccataa aaaatggtat agattgcgat atggaagatg aaatagagaa
     2041 tatatggaag cctttttatg ttttagagaa gtcaagaagt aaggagcttt ctggaactgg
     2101 tcttggtctt actatagtta gaactatact tgaagaaaat aattttagat acagggttga
     2161 aatttgtgat aaaattatag cattttatat tatatttata aaattaattt gaattaaaat
     2221 gcaaatataa agaataatta aaaaaatata gcaattattt gtttttcata tgga
//
LOCUS       DBGJFK010000140         2269 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.148, whole genome shotgun sequence.
ACCESSION   DBGJFK010000140 DBGJFK010000000
VERSION     DBGJFK010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2269
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.148"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            106..1704
                     /locus_tag="ACOIAP_003541"
     CDS             106..1704
                     /locus_tag="ACOIAP_003541"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HGZ2640411.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDVKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VISVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEVMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLVLAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            1775..2056
                     /locus_tag="ACOIAP_003542"
     CDS             1775..2056
                     /locus_tag="ACOIAP_003542"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640412.1"
                     /translation="MYKIKYIILNIIKVAVITADCPFRIPTAIDKKLFIVKVVPPNKK
                     PAKYPESTHHHDSVVRPVKSLPPRIRNKIAKEYILSCNIIKIYSLKFLY"
BASE COUNT          852 a          293 c          341 g          783 t
ORIGIN      
        1 attttttcac taaatttttt tctttttaca acaaatactc actacctttt gatataatat
       61 ttttatcaat tattattata ttcaagtttt gaaaggagta ttaaaatgag tttattagtt
      121 ttcggacata aaaatccaga cacagattca atatgttctg caatttcatt agcacattta
      181 aagaacaaac taggaataaa agcaacagct tatgctttag gagatatcag aaaagaagct
      241 aaatatgcct tggattactt taaggtagat gcacctgaaa ttttagataa tgttaggata
      301 caagttagag atttaaatta tgacaaagta gtacctttaa caccaacttc atctatatta
      361 gaagcctata accttatgga tgaaaaaaat gttaaaacac tacctgtaac ttatgatgat
      421 ggaacttttg ctggtatcat tactatgaaa gaaatagcta aaaacctact tcatcaacac
      481 tttacaacta tacacacatc actatcaaac atttgtaaaa accttaatgg tactattctt
      541 gtggattgtg gtgaagatgt aaaaggtaga gtagttactt tatcatttgg aatggagact
      601 ctaatagaga ctttaaaaga gggagatata gctattgttg gcgatagata tgatagtatt
      661 gaatatgcta ttgatacaaa agttaaactt ttaatactta ctaatcatac agagatttca
      721 aaagacttgc tagctcttgc taagataaat ggagtgtctg ttatttctgt tgaaagtgac
      781 aattataaaa cttctaatgt aataaatcaa tgtagtttct tagactctat agaagctaca
      841 gaaaatttaa ttacattcaa agaagatgat tatatggatg aaataaaaga ggttatgcta
      901 gagacaaact tcagatctta tccaatatta gatgatgata ataagttttt aggtttagtt
      961 tcaaaaggtc atctattaaa cccatctaaa aagaatgttg ttttagttga ccataacgaa
     1021 tatgctcaaa gtgctgatgg aattgaacaa gcaaacatag ttgaaataat tgaccatcat
     1081 aaacttggtg gtatttctac tgatgttcct atgtcattta gagttatgcc tgttggatgc
     1141 aatagtacta taatttatca aatgtacaaa gaaaataatg ttgagatacc ttatgaaata
     1201 gctgggcttc ttttatctgc tatattatca gatacattat tatttaagtc tccaacaaca
     1261 actgatatgg ataagaaggc ttgtgaagaa ttaagtaaaa tagcaaaagt agacatggaa
     1321 aaatacgcta tggatatgtt taaatgtggt acttctttag atgaatatac tatagaagaa
     1381 atagtaaata tggattttaa agagtttaat atgagtggac atagagttgg tattggacag
     1441 gtatttactt tagatataga ctctatattt gctaaaaaag atgagttttt atcttatata
     1501 aattcgactg attatgataa attagttctt gcagttacag atataatcaa agaaggttct
     1561 tatttaatct ataaagcaga agatagctta attgctaacg catttggtgt tgaaggggtt
     1621 caaggtacat ttgcaccagg tgttgtatca agaaaaaaac aattagttcc taatttaact
     1681 actgcaatca aaaattttaa ataatataaa gtttttaaac aataaaaaag aaggtgtctc
     1741 aaagtgaatt ttatagtcca tgaggcactc ttttttgtat aaaatcaaat atattattct
     1801 aaatatcatc aaagtagccg taattaccgc tgattgccca tttcgtattc ctactgctat
     1861 agataaaaaa ttatttatag taaaagtagt tcctccaaat aaaaagccag cgaaataccc
     1921 agaaagtact catcatcatg attcagtagt aagacctgtt aaatctcttc ctcctagaat
     1981 tagaaataaa atagcgaaag aatacatact tagttgcaac ataattaaaa tttacagtct
     2041 taaattttta tattaataat gctaatttcc acaaaaaaag aacatgtaat tagaatcttc
     2101 taacagcatg ttctttttca ttattatata ttacacttta aattattcct tgactggctt
     2161 agctggtgta aactaaacca gtctttctaa aatattaagc acttttttct tattatgttt
     2221 tttaggattt attgtctata ttattgtaaa ccaaagttat aaaattgta
//
LOCUS       DBGJFK010000141         2256 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.149, whole genome shotgun sequence.
ACCESSION   DBGJFK010000141 DBGJFK010000000
VERSION     DBGJFK010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2256
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.149"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(130..564)
                     /locus_tag="ACOIAP_003543"
     CDS             complement(130..564)
                     /locus_tag="ACOIAP_003543"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640413.1"
                     /translation="MISKNRTKYYKAILDVENKGYNLTVFIEFMLKSIMQSINEMRDM
                     HDRNSLESVLKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKRNKSRYLKAGI
                     KEIDLIDQLMEVFNNLEEIELLSREKDVYKVNEKYLKMLDID"
     gene            732..1055
                     /locus_tag="ACOIAP_003544"
                     /pseudo
     CDS             732..1055
                     /locus_tag="ACOIAP_003544"
                     /inference="COORDINATES: protein motif:HMM:NF024083.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
     gene            1420..1761
                     /locus_tag="ACOIAP_003545"
     CDS             1420..1761
                     /locus_tag="ACOIAP_003545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640414.1"
                     /translation="MLNKKNVSLIALVIILSLFTVIFVFNNRNTNDKLKEVTKNNEEI
                     VPKNLEDLSIKQLTEIRDKAIDKNLEGLREFGEDIVKKRKDLILNFEFGLVAFVNKNY
                     SNLTEKEKLIR"
     gene            1801..2145
                     /locus_tag="ACOIAP_003546"
     CDS             1801..2145
                     /locus_tag="ACOIAP_003546"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640415.1"
                     /translation="MDPSGSFFELANQSYEINEFMLKNKKNYKEWSYEYIEFLIDHLE
                     ELCKFVDFDVKDVIDIIDPTIKTDLSDEQQKSLNDKLKKMSSSETLNEKIKKEIKNWE
                     NNLNSLNMNKNW"
BASE COUNT          918 a          264 c          276 g          798 t
ORIGIN      
        1 gtactatttt ctataatatt ataacgaaat aacgtaaaaa caattattaa taaaattaca
       61 tttatagcac cagaaattaa gaatgccttt ttcttattat tcatatattc cctctctaga
      121 ttatctaaat tagtctatat caagcatttt taagtacttc tcattaactt tatatacatc
      181 cttttccctt gataaaagct ctatttcttc aagattatta aacacttcca tcaactggtc
      241 aattaagtct atttctttta ttccagcctt taagtatcta cttttattcc ttttaatata
      301 gttttccaat gtcatagaat agttatcttt actacagata tattttaata tatgttcttc
      361 tgttgctgat agagtaatgt cattttcaaa taactcttct ttcaacacac tctctaaaga
      421 attcctatca tgcatgtctc tcatttcatt tatagattgc attatggact ttagcatgaa
      481 ctctataaat acagttaaat tatatccctt attctctaca tcaagtatag ccttataata
      541 cttagttctg tttttagata tcatatatga tattgaaaac tctttaaaag tatcatatcc
      601 tttatcaatc agatatagat atgataatgc tcttgatgtt cttccattac catcactaaa
      661 aggatggata tggagattat gctaactttg tttcacaatg cttatatgag gctggagtaa
      721 cattctggac taataataat ccatggtatt attattctac tagtaataga tcaccttctt
      781 gggctggagc aagagagttt aaaatacatt gggtgaatcg aattgcatat caaacactta
      841 ctgtatcaaa ctctttaagt tttttaagac cagcaacacc tgtaagtata ttaaaaagta
      901 gtggagtagc aactcataca ctaatatcta cagataaaca ttcaaatgga tataattttt
      961 catacgctgc acattcagat gaaggcgtaa gaacaaactt gttaagtaaa cttaaaggaa
     1021 agaaaatttc ttattacaaa gtttattggg aataaagaaa agtttatgac tttaatcaaa
     1081 tgaaaattga aaagaataaa tatctatttc aaaaaatcaa taaaaattta gcagaaacaa
     1141 ctactaaatt ttattacata ataataaaat ttatttgtaa aaaagctata taagtataaa
     1201 aagaggacta atagaattta gtcccttttt atgatttaaa aatttaataa aaaaattata
     1261 tacatatgtc taaaaattag tttatcattc gttataatta tataaactat atcaaaaaag
     1321 tgttatattg tagtctttat aataagcagt aataaaggtt actctaataa actgaattat
     1381 tttttacaaa caaaatgctt attaaaaagg aggtttaata tgttaaataa aaaaaatgta
     1441 agtttaattg ctttagtaat aattttaagt ctatttactg ttatatttgt tttcaataat
     1501 agaaatacaa atgataaatt aaaagaagtt actaagaata atgaagaaat agttcctaaa
     1561 aacttagaag atttaagcat aaaacaatta acagaaatta gggataaggc tattgataaa
     1621 aacttagaag gacttagaga gtttggagaa gatatagtaa aaaaacgtaa agatttaatt
     1681 ttaaattttg aatttggatt agttgctttt gttaacaaga attatagtaa cttaacagaa
     1741 aaagagaaat taataagata aattaatatt gttaactatg aaagctctat aaatgaaata
     1801 atggatcctt caggttcatt ctttgaatta gcaaatcaaa gttatgaaat taatgagttc
     1861 atgttaaaaa acaaaaaaaa ttataaagaa tggtcatatg aatatataga attcctaatt
     1921 gatcatttag aagaattgtg caaatttgtt gatttcgatg taaaagatgt aatagatatt
     1981 attgatccta caataaaaac agatctttca gatgaacaac agaaatcctt gaatgataaa
     2041 ttaaagaaaa tgtcttcaag tgaaacttta aatgaaaaaa ttaaaaagga gataaaaaat
     2101 tgggaaaaca atttaaatag tttaaatatg aacaaaaatt ggtaatatct caaaataagt
     2161 ctggaaatat ttatgtgtat tctttaacta aaaatttatt ttttaataga aataaagcaa
     2221 gattaaaagt tgcaagactt caagaacata tagcta
//
LOCUS       DBGJFK010000142         2124 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.150, whole genome shotgun sequence.
ACCESSION   DBGJFK010000142 DBGJFK010000000
VERSION     DBGJFK010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2124
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.150"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            48..>2124
                     /locus_tag="ACOIAP_003547"
     rRNA            48..>2124
                     /locus_tag="ACOIAP_003547"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          632 a          424 c          607 g          461 t
ORIGIN      
        1 aaaattatcg aagttgatag cttctaatct atcaaacctt tttaactggt caagttatta
       61 agggtgcagg gcggatgcct tggcactagg agccgatgaa ggacgtgata agctgcgata
      121 agcttcgggg agttgcacgt aaactttgat ccgaagattt ccgaatgagg aaactcactt
      181 agagtaatgt ctaagtatca ttaagtgaat acatagctta atgaggggaa ctcagggaac
      241 tgaaacatct aagtacctga aggaagagaa agaaattcga ttccgtaagt agcggcgagc
      301 gaacgcggat tagcccaaac caataaagtt ttctttattg gggttgcgga catatcataa
      361 cgaagaggta tcgtaattga agaggtttgg aaagacccac cacagaaggt aatagtcctg
      421 tatgttaaac gagaagactt cagatatgat ccagagtacc acgggacacg tgaaaccctg
      481 tgggaagcag gagggaccac cctccaaggc taaatactac ctagtgaccg atagcgtata
      541 gtaccgtgag ggaaaggtga aaagaacccc gggaggggag tgaaatagaa cctgaaaccc
      601 tgcacttaca agctgtggaa gcacatttct tgtgtgaccg cgtacttttt gtagaacggg
      661 ccaacgagtt acgttaagta gcaaggttaa gcacttaagg tgtggagccg tagcgaaagc
      721 gagttttaac tgagcgttca gttacttgac gtagacccga aaccgggcga cctacccatg
      781 agcaggatga agcgaaagta aaatttcgtg gaggtccgaa cccacgagcg ttgaaaagct
      841 cggggatgac ttgtgggtag cggtgaaatt ccaatcgagc ccggagatag ctggttctcc
      901 ccgaaatagc tttagggcta gcctcaaggt gagagatacg gaggtagagc actgaatgtc
      961 ctagggggta ttgcacctac cgaagactat caaactccga atgccgtcat cttatacttg
     1021 ggagtcagac tgtgggtgat aagattcata gtcgaaaggg caacagccca gatcgtcagc
     1081 taaggtccct aaatgtaagt taagtggtaa aggatgtggg attgcacaga caaccaggat
     1141 gttggcttag aagcagccac tcattcaaag agtgcgtaat agctcactgg tcgagtgatc
     1201 ctgcgccgaa gatttccggg gctaaaactt actaccgaag ctacggcatc agtaatgatg
     1261 ggtaggggag cttcccatac gggttgaagc atgaccgtaa ggacatgtgg acagtatggg
     1321 agtgagaatg ttggcatgag tagcgagatg tgggtgagaa tcccacaggc cgtaaaccca
     1381 aggtttccag gggaaggttc gtccgccctg ggttagtcgg gacctaagct gaggccgaaa
     1441 ggcgtaggtg atggacaaca ggttgatatt cctgtactac cgataaccgt ttgagagaag
     1501 ggatgacaca gtaggataag ctaagcacac tgttggttat gtgtgcccaa gcattgaggc
     1561 agtcaaagta ggcaaatccg ctttgataat gctgggatgt gatggggagc gaaatttagt
     1621 agcgaagtag ctgatttcac actgtcaaga aaagtctcta tcgaggttaa aggtacccgt
     1681 accgcaaacc gacacaggtg ggtgaggaga gtatcctaag gccagcgaga gaactgttgt
     1741 taaggaactc ggcaaaatga ccccgtaact tagggataag gggtgccacc atcaggtggc
     1801 cgcagagaat aggcccaagc gactgtttac caaaaacata ggtttctgct aagtcgcaag
     1861 acgatgtata ggagctgacg cctgcccggt gctggaaggt taaggggatc tgttagagca
     1921 atcgaagcag tgaacttaag ccccagtaaa cggcggccgt aactataacg gtcctaaggt
     1981 agcgaaattc cttgtcgggt aagttccgac ccgcacgaaa ggcgtaacga tttgggcact
     2041 gtctcaacaa cagactcggt gaaattgtaa ttccggtgaa gatgccggat acctgcgaca
     2101 ggacggaaag accccatgga gctt
//
LOCUS       DBGJFK010000143         2089 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.151, whole genome shotgun sequence.
ACCESSION   DBGJFK010000143 DBGJFK010000000
VERSION     DBGJFK010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2089
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.151"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..332)
                     /locus_tag="ACOIAP_003548"
     CDS             complement(<1..332)
                     /locus_tag="ACOIAP_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2640416.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMGFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDANSIILKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQG"
     gene            complement(818..>2089)
                     /locus_tag="ACOIAP_003549"
     CDS             complement(818..>2089)
                     /locus_tag="ACOIAP_003549"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2640417.1"
                     /translation="SISKTTANQIKSTVNASQTRLNGSNRYETSLLIAKEIDKNHDVE
                     KVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTYKWLKSEDLQSAYFIGGP
                     QMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYTDDELEAVLVAKSDVLV
                     DALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVYKIGGGLTSKVMSSIASS
                     LSKHNTTPTDPGTSGGKTVMIDPGHGGSDTGTTGKPLGGIKEKDYTLNTSLATTEYLR
                     SKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNASDTTGNGVEVFYKLKDKD
                     GGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLYVLRNNDMPAVLVECAFL
                     DNEKDMSLLNTSDKVKEMGTQIGKGIEDSLK"
BASE COUNT          638 a          350 c          251 g          850 t
ORIGIN      
        1 ccttgtagtt cccaaacatt tagatattct gggtctttat tataattaat agttccctca
       61 tacgactcag ttgattgatt gtagtttaga gttgtgtcta atggcatatc ataacattta
      121 tattttaata taatgctatt tgcatctggt ttttctttaa atttgacgct aacttttgat
      181 ttactaccta aaacgatact ttttttctct aagtttatat ttaaatcagc attattttcc
      241 atagcattag attcagtagc aaatcccatt gtaggtgcaa cgattgccat tgaaagaatc
      301 cctgttgtta ataattttgt atttcttctc atattaatct ccttatttaa cataaatttc
      361 tactttgttt tttaaccttt taacttttga aaatatggca aagtgtatct atctaaaaat
      421 ataaataagt acataaagat aaacttataa aactcaaaaa ataaaaaaat taaatatatt
      481 taatacattt aattatttat actatagcat ttattaccat aaaaatccac aaaaaaacac
      541 aataaagtat agtaattgaa cttttactgt gtatcacaaa tgaatacgcc aactcttgac
      601 gattagctat aaccttaaaa tatgtaaatt ctttatataa cataaattct tttacaatta
      661 actacaaaaa gactatatat acatcactta gcacttatat gcacaatgta tatatagtct
      721 ttattactat tgtaattaca ttcttatctt atagctttag ttaaaattta aaattgcaaa
      781 ttaatttatt ttaaattttc tatgctctca ttgttggcta ttttaatgaa tcttctattc
      841 ctttacctat ttgtgtaccc atttctttta ctttatctga tgtattaagt aaactcatat
      901 ctttctcatt atctaaaaat gcacattcta caagtacagc tggcatatca ttatttctta
      961 aaacatataa ataatctttt gtagggtcag ttgatagtgt tcttgttttt gcacctctat
     1021 tttttagatt aaatttctct aaaattctat ttaatatatt tgtagctaca gtcttagtag
     1081 ttcctccatc tttgtcctta agcttataaa atacttctac accattccca gttgtatcag
     1141 atgcattata gtgtatactt gtaaataaat ctggtctcaa agagttagat agagcagttc
     1201 tatttccaag agataaagtt ttatctgtgt ctcttgtcat tattacattg aacccctttg
     1261 aacgtaaata ttcagttgtc gcaagtgaag tatttaaggt atagtctttt tctttaatac
     1321 ctcctaatgg tttacctgtt gttccagtat ccgaaccgcc atgccctggg tcaatcataa
     1381 ctgtcttccc accactagtt cctgggtctg ttggagttgt attgtgttta gataatgatg
     1441 atgctataga actcattacc ttagaagtca atcctcctcc tattttatat actttattgg
     1501 ctgatttagc ttctaagttt tctttatggt atgcagatac atacgtcttt ggtgttataa
     1561 gtattggaga ttttaagtta gcagccaatg gacctgctgc taaagcatca acaagtacat
     1621 ctgatttagc tactaaaaca gcttccaact catcatctgt atagaatttt tttattacat
     1681 ttgcatttgt ttcgtgtcta tctgctccgt atactctatt attagtaaca ctatccttag
     1741 ttattccatt taccttattt ataacatttg ttgatatcat ttgaggacca cctataaaat
     1801 aagcactttg taaatcctca ctctttaacc atttatacgt attatctgta atactatctt
     1861 tatcagttag tattattggt tgcttatctt gacctgcttt tgctgctatc gtaagtgcat
     1921 ctacttctcc accattagca tttgttatgt atactttttc cacatcatga tttttatcta
     1981 tttcctttgc tatcaataaa gatgtctcat atctattaga gccatttaga cgtgtttgac
     2041 tagcatttac agtcgattta atctgattag cagtagtttt agaaataga
//
LOCUS       DBGJFK010000144         2033 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.152, whole genome shotgun sequence.
ACCESSION   DBGJFK010000144 DBGJFK010000000
VERSION     DBGJFK010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2033
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.152"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(250..1578)
                     /locus_tag="ACOIAP_003550"
     CDS             complement(250..1578)
                     /locus_tag="ACOIAP_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGZ2640418.1"
                     /translation="MESNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMIVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPASELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYSIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGIKR"
BASE COUNT          740 a          351 c          215 g          727 t
ORIGIN      
        1 tttgataaaa aaatacttta aaataaagta ttttaaagca aataattttt tagatgttta
       61 attttgtaat ccaaaaacta aaaataaaat aaatacctta agataagctt tttagttcat
      121 gaaacactct ttttttataa aatcaaacct atctttgtca ttttaacaat aaaaaagaga
      181 cttctctcta ttttgagaca gtctctttta ttttttaaat aattataaag catttgtaaa
      241 ctacttaatt tatcttttta ttcctctagt catataagca tacactggta aacctatagc
      301 tgttattaca agtcctccta tagatatcat agtagttttc atacctgcaa aacacaattg
      361 attaactaca acaaatatac cacttgctat agctattatc ggaacaatag gatataatgg
      421 cactttatac tctcttggta tatttggatg agtctttcta agtttcatta cccctataaa
      481 agttaataca tagaatatcc aagtagcaaa tacagctaag tcagttaata aattaaattg
      541 acctgacaaa gcatatatag atgcaataac agatactaat gctattgcat ttgctggaac
      601 ttgagcagaa tttaatttag agaatatact atattttggt aaagtcttat ctgtagctaa
      661 agtgtatgcc acccttgaac cagttagtaa aaatccattt aatgctccaa acactgaaat
      721 taatatacct acagatatta ttttcccacc cattgaacca aatataactt cagcaactgc
      781 tgatgcagga gaagcataat ttgctaattc actagccggt aatacccaaa gatatgctaa
      841 atttattata aagtaaacag ccataacaac tgataatcca cctattatag cttttggaag
      901 gtcttttcca ggattcttca tttctccagc caaagtacca acattcatcc atccatcaaa
      961 tgcaaataat atagcaatta aaacttgacc taatacacta cctagactta atccctcacc
     1021 aaccataggc gtaagtattg gattatttcc accaccttta ataaatccaa caatcattat
     1081 taaaataagt ggtattaatt tacaaattgt agaaacagtt tgtataactc ctccagtttt
     1141 tgaacccagc atattaagcc ctgcaactat tactataatt ccaattgcta ttggaagtaa
     1201 gagtgatgga ctaccaatta gtgctgatgc ttgttctccg aatataacac ctaatgctgc
     1261 catcatccct ggataaaata atacaatttg catccatcca gttaaaaaac ctaatttttc
     1321 tccataaatt tcttttatat ataccatcat tccaccagtt tttggtatcg caactgatac
     1381 ctctgcagct gtaagaccag ctgttatagt tatgattcca gctattaacc atgccaatat
     1441 accaagacct ggagctcctc cagttaatgt ataaactgct tgtggtttaa aaaatacacc
     1501 cgctcctata acagaaccaa caacagttga taatgccgct gatacgccaa gagtcttttt
     1561 cagttcatta ctttccattt tcttcctcct cattaatcct atttaatttt aatttcatag
     1621 ttaaataagc atatattatg ccaatactat agaaaaatag ctttattatt tattaaaata
     1681 aaataaactc tacttagctt ttgtaatttt ttgcttttaa tcaagttcaa atataaaaaa
     1741 attataaaaa acaaaaatct aaattaatga tacttattaa aagtaaaaat attttttata
     1801 ttgtataata tacattgtat atttataaca taaaaaatag attataacta ttaagttaaa
     1861 ttcattcaag attttttgca ataaaatttc attttttcaa aaagatttta gcttctttct
     1921 atagttttct atatttaatg ccttttatat ggtatagtat tattttttct tgttttatag
     1981 tctattttat attaataaat aatttgacaa tttattataa cccaatttaa acc
//
LOCUS       DBGJFK010000145         2021 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.153, whole genome shotgun sequence.
ACCESSION   DBGJFK010000145 DBGJFK010000000
VERSION     DBGJFK010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.153"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..1259
                     /locus_tag="ACOIAP_003551"
     CDS             <1..1259
                     /locus_tag="ACOIAP_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF6179 domain-containing protein"
                     /protein_id="HGZ2640419.1"
                     /translation="YINKLGDIEKRVVELTAKNVKKVYLRGIEILEEELVRLKNFYEL
                     MMSRKLDTNSIAYNDTLMELSSFFKSYIIKFEAQDIPVSIDYPLALDDMDIQGIYYVK
                     NYIESIDIENRFCNLFKKKDREKLFYDYGVTYKIDCDVILVNLFELIINNCIFSTILG
                     NEVTNLEISEYEYEFLEKQFKNICNNIAEDKVIVSEESNIIELIEVDDSFNTEADSNL
                     DYNDFEKITLILMEAIEVLVKRLRIEDEVVIRYIKKYEKRFIESVLSSIKSNTFKSMV
                     TVSKNKNEQLESYIVDDESKLDDESFRKIFNEILDSTSIIEKIRIIKENINAKKDFID
                     ILESECLFGEEYLMLFASLSELELAILGSVVFYEDIRMREINILEFLLNKKTETTLWK
                     IEYLKFMKRQSEDKIRSIEEHMNKIN"
     gene            1343..1852
                     /locus_tag="ACOIAP_003552"
     CDS             1343..1852
                     /locus_tag="ACOIAP_003552"
                     /inference="COORDINATES: protein motif:HMM:NF013696.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGZ2640420.1"
                     /translation="MKEHIINNIEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGESGH
                     GCGHNLLGVAGVGAVVSTKKLIEENKFSGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFD"
BASE COUNT          843 a          158 c          383 g          637 t
ORIGIN      
        1 cctatataaa taagcttgga gatatagaaa aaagagttgt ggagttgact gctaagaatg
       61 ttaaaaaagt gtatcttaga ggtattgaaa tcttagagga agaattagtt agactaaaaa
      121 atttttatga actaatgatg agtagaaaat tggatactaa ttcaatagcg tataatgata
      181 ccttgatgga gctatcaagt ttctttaaaa gttatattat aaaatttgaa gctcaggata
      241 ttccagtaag tatagattat ccattggcat tagatgatat ggatattcaa ggaatttatt
      301 atgtaaagaa ttatattgag agtatagata tagaaaatag attttgcaac ttatttaaga
      361 aaaaagatag agaaaaatta ttttatgatt atggggtgac ttataaaata gattgtgatg
      421 ttatacttgt aaatttattt gaacttatta taaataattg tattttttct acgattttag
      481 gaaatgaagt gactaattta gaaatttcag aatatgagta tgaattttta gaaaagcaat
      541 ttaaaaatat atgcaataat attgctgaag ataaagttat agtatctgaa gaaagtaata
      601 taattgaatt gattgaagta gatgatagtt ttaatactga agcagatagt aatttggatt
      661 ataatgattt tgaaaaaata accttaatac ttatggaagc aattgaagtt ttggtaaaaa
      721 gattaagaat agaagatgaa gttgtaataa gatatattaa aaaatatgaa aaaagattta
      781 ttgaatctgt gctaagttca ataaaaagta atacttttaa aagtatggta actgtaagta
      841 aaaataaaaa tgaacaatta gaaagttata ttgtcgatga tgaaagtaaa ttggatgatg
      901 agtcgtttag aaagatattc aatgagatat tagacagtac gtctataatt gaaaaaataa
      961 gaataataaa ggaaaatatc aatgctaaaa aagattttat cgatatcctc gaatctgaat
     1021 gtttatttgg agaagagtat ttaatgttgt ttgcttcatt aagtgaatta gaattagcaa
     1081 tattgggtag tgtagtgttt tatgaagata ttagaatgag agaaattaat atattagaat
     1141 ttctattaaa taagaaaact gaaactactt tatggaaaat agagtacctt aaatttatga
     1201 agagacaaag tgaagataag atacgctcca tagaagaaca tatgaataaa attaattaac
     1261 aaaaaattgt gaataaatag aatgttagta tataatataa tttatgaagc atatcaaaaa
     1321 tacatatatt tggaggaaaa ttatgaaaga gcatatcata aataatattg aagaaataag
     1381 agaagaatta atagatttat ctaagaaaat atgggaaaat ccagaattag cttttgaaga
     1441 aaagtatgca agtagcatcc aaaaagaata cttaaagtca aaaggattta aaattgaaga
     1501 agtagaaaat ttacctactg gatttatagc aagttttgga gagggtaaac ctgtgattgg
     1561 catacttgga gaatatgatg ctttaccaga gctatcacaa tgtgtgagtg cagaaagaaa
     1621 gccattggta gaaggagaat ctggacatgg atgtgggcat aacctattgg gtgtagcggg
     1681 tgtaggagct gttgtttcta caaaaaaatt aatagaagaa aataaattta gtggaacaat
     1741 aaaatatttt ggttgtcctg ctgaagaaga aggtggagga aagacagtta tgtgtataaa
     1801 tggatgtttt gatgatgtgg attgtgcatt tacatggcat ccttttgatt aaaaaatagc
     1861 tacgcacact cgtgatttta gtcatgagtt agtagctaaa atagtcagca tatagggaaa
     1921 cttatatgta gagataggat agaacctatc caatactact tgaattgctg gaaaacccta
     1981 aagctaacca aactaaaaca taaggatgaa ataaacctaa g
//
LOCUS       DBGJFK010000146         1842 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.154, whole genome shotgun sequence.
ACCESSION   DBGJFK010000146 DBGJFK010000000
VERSION     DBGJFK010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.154"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            197..856
                     /gene="tcdC"
                     /locus_tag="ACOIAP_003553"
                     /pseudo
     CDS             197..856
                     /gene="tcdC"
                     /locus_tag="ACOIAP_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
     gene            complement(1223..>1842)
                     /locus_tag="ACOIAP_003554"
     CDS             complement(1223..>1842)
                     /locus_tag="ACOIAP_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGZ2640421.1"
                     /translation="IINDKHFYFNTDGIMQIGVFKGPDGFEYFAPANTDANNIEGQAI
                     RYQNRFLYLHDNIYYFGNNSKAATGWVTIDGRRYYFEPNTAIGANGYKIIDNKNFYFR
                     NGLPQIGVFKGPNGFEYFAPANTDANNIDGQAIRYQNRFLHLLGNIYYFGNNSKAVTG
                     WQTINGNMYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
BASE COUNT          698 a          235 c          271 g          638 t
ORIGIN      
        1 caagaaaatt atattataat ctgacatttt taccttattt tccaaaatat attgaatttt
       61 cttgctttat tttgtaaaat tatgcttagg ggaaatatat tttaggaaaa tatgaatata
      121 taatttttag tcaactagtt attttaagtt tttaaatttt aaaataaaat atatctaata
      181 aaagggaaat tgtattatgt tttctaaaaa aaatgagggt aacgaattta gtaatgaagg
      241 aaaaggaatc tctaagaaaa taattaaatt ctttaagagc acaaagggta ttgctctact
      301 ggcatttatt tttggtgtgt tttttggcaa tatatcctca ccagcttgtt ctgaagacca
      361 tgaggaggtc atttctaatt aaacatcagt tatagattct caaaaaacag aaatagaaac
      421 tttaaatagc aaattgtctg atgctgaacc atggttcaaa atgaaagacg acgaaaagaa
      481 agctattgaa gctgaaaatc aacgtaaagc tgaagaagct aaaaaggctg aagaagagaa
      541 gaaaggatat gatactggta ttacttatga ccaattagct agaacatctg atgattataa
      601 gtacaaaaag gtaaaatttg aaggtaaggt tattcaagtt attgaagatg gtgatgaggt
      661 gcaaataaga ttcgctgtgt ctggaaatta tgataaggtt gtactatgta gttaaaaaaa
      721 atcaataact ccttcaagag tgttagagga tgattacata actataagag gtataagtgc
      781 tggaactata acttatgaat caactatggg tggaaacata actataccag gaatagctgt
      841 agagaaaatt aattaatatt gttttgtatt atagttaata tttttgtatt atagtcaata
      901 tgtttaaaga tgtttttata attgcaaata aacagttaca agactctaaa ttagtttttg
      961 cttttagcat attatctatg ttctagtaac tattaattat ttagtattaa tatttccata
     1021 tatgaatttt attataaagt agtaaaatta tttgtttaaa atttagatta tcgtcaagaa
     1081 taatagatta ttaaatgata gaaaaatttt aactaaaagt catgtattac aataacacat
     1141 gacttttaat taaatatcaa tatttattat ataaaaataa tttctgagta tcacatgaat
     1201 aaatttttgt caaacatata ttctagccat atattccagg ggcttttact ccatcaacac
     1261 caaagaaata tataacacca tcaatctcga aaagtccacc agctgcagcc atagcagtat
     1321 caggcataaa gtaatacata ttaccattaa tagtttgcca tccagtaact gcttttgaat
     1381 tattaccaaa gtaatatata ttgccaagta aatgtaggaa tctattttga taacgtatag
     1441 cttgaccgtc tatattgtta gcatccgtat tagcaggtgc aaagtattca aatccattag
     1501 gtcctttaaa cactcctatc tgaggtaaac catttctaaa gtaaaagttt ttattatcaa
     1561 taattttata accattcgca cctatagctg tattaggctc gaagtaatat ctcctaccat
     1621 caatagttac ccaaccagta gctgcttttg aattattacc aaagtaatat atattgtcat
     1681 gtaaatatag gaatctattt tgataacgta tagcttgacc ttctatgttg ttagcatccg
     1741 tattagcagg tgcaaagtat tcaaatccat caggtccttt aaacactcct atctgcataa
     1801 taccatcagt attaaaataa aaatgtttat cattaataat tg
//
LOCUS       DBGJFK010000147         1834 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.155, whole genome shotgun sequence.
ACCESSION   DBGJFK010000147 DBGJFK010000000
VERSION     DBGJFK010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1834
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.155"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            135..1184
                     /locus_tag="ACOIAP_003555"
     CDS             135..1184
                     /locus_tag="ACOIAP_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGZ2640422.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWVQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1333..1680)
                     /locus_tag="ACOIAP_003556"
     CDS             complement(1333..1680)
                     /locus_tag="ACOIAP_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGZ2640423.1"
                     /translation="MHENKKNLLDGSLAQYNDVAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          678 a          250 c          282 g          624 t
ORIGIN      
        1 aagactaaac ataaaactga aacttattat taagtttttg tagaaatatt ataagtatag
       61 atacattttt gtaacaacta caatgaatat ttaatactat atactattcg tatgtcttat
      121 gggaggtatt tattatgttt aaaaaaatag tcgcaatagc aagctctatc attgtaagta
      181 caatatgtct aactggatgt gattttaact ctaatgacaa aaaagatgaa tcttcttcgt
      241 ctaaaaatct ggataaagta actatagcag aagttactca ctctgttttt tatgctccac
      301 agtatgctgc tattacgaaa ggattctttg aagatgaagg tataaagatt gaccttataa
      361 atacccaagg tgcagataaa actatggcag ctttaatttc aggtgaagca aacgtaggtt
      421 taatgggccc tgaagcatct atatatgtat ataatcaaaa caaaaacgat tatgcagtga
      481 actttgctca attgacaaaa agagatggta gttttctagt tgctaggaaa aaaatgccta
      541 atttctctta taatgattta aaaggaacag aaatattagg tggtagaaaa ggtggagttc
      601 cactaatgac ttttgaatat gttctaaaag aaaaaggtct tactattgga gaaaacctaa
      661 aggcaggcaa tgttaatgta agaactgatg tacaatttgg tgtaatggct ggagcttttg
      721 caggtggaga gggggacttt acaacagcat ttgaacctac tgcaacagca atggaaaaag
      781 aaggtagtgg atatatagtt acatctatag gaaaagattc tggagaaata ccttttacag
      841 catactctac tacaagatca tacatgaaaa acaataaaga tttaattcaa agatttacaa
      901 atgctgttta taaaggtcaa ttatgggttc aacaagcatc tagcaaagaa gtagctaagg
      961 ctatgcaacc tttctttgaa gatatatctt tagaagattt aacaacagtt gtagatagat
     1021 ataaatcaat agatgcatgg tctcaaaacc ctgtattaaa agaagaaggt ctgaagaaat
     1081 taatgactgt tatgaaggaa gctaaagaat tagataagga agcaccttat aaagatatcg
     1141 taaacactga gtttgcaaac aatgctataa agaatattaa ataaaatata ttacttttgc
     1201 ctagatattt tctcgatttt atgattaaaa ttaacaaaaa tataaaaaga gccttttaaa
     1261 agactctttt tatatttgag attaaagttt atataataaa atagaatcaa agtactaatt
     1321 gtacttatat atctatcctc tatattctgc tccagcatta atttttgtaa tttgaacagc
     1381 taccatttct tcattgcttc cattagtaat ttcatgccat tctcctgttg gtacaaatac
     1441 agtatcgccg ttttttacat cacattcatg ctcaccaagt ttcattttac cttctccttt
     1501 taggaacaca aatatttgtt ctccattagg atgtctatga gcattaagaa cttgattagg
     1561 tttaaaataa taaacttctg aagttatatc gttaccagca aatactggta tttttggaac
     1621 tgctacatca ttatattgag ctaagcttcc atctaataga ttctttttat tttcatgcat
     1681 actagaaata cctcttttct atattatata tttactatta ttattccaat ataagaaaat
     1741 agtattctca tcttgcataa taggaataaa attcttttat ttttaaatac taaggattat
     1801 attattttta tagttataga aatataagct ttat
//
LOCUS       DBGJFK010000148         1705 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.156, whole genome shotgun sequence.
ACCESSION   DBGJFK010000148 DBGJFK010000000
VERSION     DBGJFK010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1705
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.156"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            448..825
                     /locus_tag="ACOIAP_003557"
     CDS             448..825
                     /locus_tag="ACOIAP_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2640424.1"
                     /translation="MMIRKIPQAELKVIKFIWRVDNTVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDKYTNYAIIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            818..>1705
                     /locus_tag="ACOIAP_003558"
     CDS             818..>1705
                     /locus_tag="ACOIAP_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HGZ2640425.1"
                     /translation="MNNYMIYVFDNLIKTTIVCSLGICLLLFLKRYVFKKFSKRFNYY
                     IWVVIVFRMLLFLFNYTVIYEVKEPKENIIGNNLIRIDISIDNNFMLYLAYLWLVVTI
                     VIAVYTFVKYTRFKNLVVDVSYDIEDNDVNCIYKNLLKKLNIKKKIELRSSDELISPA
                     GMGLFKSYIFLPDYPYSKDELNWILKHELMHFKNKDILIKFLVFSVKTIYWFNPLVYI
                     MSNKVNLDCELCCDESVLMDCSLEDKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKSGILVLLI"
BASE COUNT          698 a          130 c          255 g          622 t
ORIGIN      
        1 atgcaaaagc tcttttttta taatttatta ataaggtata attataaaaa tcttattcaa
       61 taagattcat aattaattta gatatatttg taaataatca gtataaaaca gatattttaa
      121 taatacaaag atacaattag gagatagtta aaatttatta gatattactc tagtttattt
      181 taaaaaaagt attataatat tccttgtgta aaaatatagg gatttttatt aaacaatatt
      241 aatgtggaaa taccattctg tactattata attaaatata taaaaataaa aatatttgaa
      301 caactatctt ttaaaatata acttttaata tttaaaaaat tagaaaatta atataaatac
      361 aaaaattcac attttttcat aaagtgtttg actaaaaaat tcacatattg tagaattaag
      421 gtagcaagag ttttgaggga ggtgtaaatg atgataagaa aaataccaca agcagaacta
      481 aaagtaataa aattcatttg gagagtagat aatacagtaa catcaaaaga tgttattgag
      541 gttatggaac aaaaatatgg ctggaaacaa actactacac tgacactttt atctaggctg
      601 gtaaaaagag ggttcttaga tgctcaaaaa atagataaat atacaaatta tgcaataata
      661 gtaaaacaca aagattattt aagttttgag acaaaggatt tcctaagtaa tatacatgat
      721 gattctttga aaagtttaat ttcagcatta catgatgatg aaaatatagg taaagataag
      781 ctagattttt tagaaagtta ttttgataat ttaaaagatg aataattata tgatatatgt
      841 ttttgacaat cttataaaga caactattgt atgtagtctt ggtatttgtc tattattatt
      901 tttgaaaaga tatgtgttta agaagtttag taagcgattc aattattata tttgggtagt
      961 aatagtcttt agaatgttac tttttctatt taattataca gtaatatatg aagtaaaaga
     1021 gcccaaagaa aatataatag gaaataatct tatacgaatt gacatttcta tagataataa
     1081 ttttatgctg tatttagctt atttatggtt agttgtaacc atagtcattg cagtttatac
     1141 atttgtaaag tatacaagat ttaaaaatct tgttgttgat gtatcttatg atattgaaga
     1201 taatgatgta aactgtatct ataaaaattt gttgaaaaaa ttaaatataa aaaagaaaat
     1261 tgagttaaga agttctgatg aattgataag tccagcgggg atggggttat ttaaatcgta
     1321 catatttttg ccagattatc cttatagtaa agatgagcta aattggattt tgaaacatga
     1381 attaatgcat tttaaaaaca aagatatttt aataaagttt ttagtttttt ctgttaaaac
     1441 aatatattgg ttcaatccac ttgtttatat aatgagtaat aaagtaaatc tagattgtga
     1501 attatgttgt gatgaaagtg ttttgatgga ttgttcttta gaagataaga aagaatatgc
     1561 attagcactt ataaagtcaa ttaaacttag taagaattat aatagtggta ttttgacgac
     1621 tgaatttaat aaaacaagtt tggaaaagag acttgacagt attgttaaga aaaaaggtaa
     1681 aagtggaata ttggtgttat tgatt
//
LOCUS       DBGJFK010000149         1672 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.157, whole genome shotgun sequence.
ACCESSION   DBGJFK010000149 DBGJFK010000000
VERSION     DBGJFK010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1672
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.157"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            309..1418
                     /locus_tag="ACOIAP_003559"
     CDS             309..1418
                     /locus_tag="ACOIAP_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640426.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYDNMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVTLIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRIHIFDKETTLAIR"
     gene            1448..>1672
                     /locus_tag="ACOIAP_003560"
     CDS             1448..>1672
                     /locus_tag="ACOIAP_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HGZ2640427.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNSIYVIDF
                     LDKNNLDNLKGNFYLIYQPHIEFEYLKNIFY"
BASE COUNT          689 a          210 c          223 g          550 t
ORIGIN      
        1 attatataca atcaatacaa tcttaattat attattttta tactcctcat tgttaatcta
       61 aactattaat ataatactat ttccttataa attaaattga catttaaatc ccatgttgtt
      121 gaactaaaaa ctatatacta ttatacataa aacttttcta aattaaaata cattttttaa
      181 attaaaaaac tattagtcta aatttttaat atacatattg aacaaataca tttgttcatt
      241 ttacacattt aatataataa aaaaatttga tactatataa ttaaaattta aatatcaagg
      301 agaatattat gtcagaagta attttaaaaa atatatcaaa actttactca aatggattta
      361 atgcagtaaa aaatataaac atagacatta aagataaaga atttatcgtt ttagtaggac
      421 catctggttg tggtaaatcg actacactta gaatgattgc tggtcttgaa gaaatctctg
      481 aaggagaact atacattgga gataaacttg tcaatgatat agaaccaaaa gatagagata
      541 tagctatggt ttttcaaaac tatgctctat atcctcactt atccgtctat gataacatgg
      601 catttgcact taaacttaga aaattgccta aagatgaaat agacaaaaaa gttaaagagg
      661 ctgctaaaat attagattta ctacctcttt taaataaaaa acctaaaaca ttgtctggag
      721 gacaaagaca aagggttgct ttaggacgtg caatagttag aaatcctaag gtattcttaa
      781 tggatgaacc tctatccaac ttagatgcaa agcttagaac tgctatgaga acagagataa
      841 ctaagctaca ccaacagctt ggaactacat ttatctatgt aacacacgac caagttgaag
      901 ctatgactat ggctgataga atcgtagtaa tgaaagatgg agtggttcaa cagattgcaa
      961 ctccacaaga tgtatacgat tatccagcta atatatttgt tgcaggattt attggagcac
     1021 cacagatgaa ttttattgat gtaacattaa tagaagaaaa tgatgaaatt tatgcacaaa
     1081 atgaacatat taagcttaaa ttaaataaag aaaaacacta tgatttaata aaagacaatt
     1141 atattaataa tgaagttgtt ataggtatca gaccagaaga tattcatgta gaagatactt
     1201 ttattaaatc taatccagat acttgtttta aatcaagaat tgaaataaaa gaacttatgg
     1261 gagcagaaac ttatgctcac ttaaagctag gcgaaaatac tataacaatt agatttgaca
     1321 gtaaaaacag aattaatgtt ggtgatgact taacactttc agttgataac agtagaatac
     1381 acatatttga caaagaaact actttggcta taagataaga atataatctt atttttaagg
     1441 agactttatg gaagagttaa aggatttttt agaaagacaa cttaataaaa aaataaatat
     1501 ctatccatat gaaaaccaaa agttagatgc tagtagccat ttagttactt tcaataattc
     1561 tatttatgtt attgattttc tagataaaaa taatcttgat aatttaaaag gcaactttta
     1621 tttaatttac caacctcata tagaatttga atatctaaaa aatatttttt at
//
LOCUS       DBGJFK010000150         1655 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.158, whole genome shotgun sequence.
ACCESSION   DBGJFK010000150 DBGJFK010000000
VERSION     DBGJFK010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.158"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            71..682
                     /locus_tag="ACOIAP_003561"
     CDS             71..682
                     /locus_tag="ACOIAP_003561"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005777 - peroxisome [Evidence IEA];
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003986 - acetyl-CoA hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_function: GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035539 - 8-oxo-7,8-dihydrodeoxyguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0015938 - coenzyme A catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HGZ2640428.1"
                     /translation="MINDIKNKFKDYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            987..1325
                     /locus_tag="ACOIAP_003562"
     CDS             987..1325
                     /locus_tag="ACOIAP_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HGZ2640429.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVTFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
BASE COUNT          666 a          179 c          207 g          603 t
ORIGIN      
        1 aatcataatt atatattatt gttaaaactc aattatataa tttttaataa tattatttta
       61 ggaggtaaaa atgataaacg atattaaaaa taaattcaaa gattacaaac catatataaa
      121 tggatacaag aatatgaaga gagcatctgt tttaattcca atagtagaaa taaataacac
      181 acactatata ttatttgaag ttcgctcaaa aaatttgaag catcaaccta gcgaaatttc
      241 ttttccaggt ggtaaaatag aatcaggtga gactccatat gaagctgtta ttagagaaac
      301 ttgtgaggaa cttggaactt ttagtgacaa tatagaagta atatcaagtc ttgacctcct
      361 tataacacca gtaaagttta tcatacatcc atacttagga tatataaaaa atattaataa
      421 tttaaatata aacaaggatg aagttgacca tacttttttg gttcctataa aatatctttt
      481 agagaatcct ccaaatactt atagtaatac tgtaaaagtt tttccagatg aaaatctacc
      541 atatggttca attccaaacc aaaaagatta taaatttgaa agtggaagtt atcctattct
      601 gttttataaa tataaagatt atgtaatttg gggaatgaca gcaaaaatac tagaaaactt
      661 tttaaatttt ttatcagaat aacacttata ataaatcatt aaaactttta cataagaaat
      721 tcataaaagt ttctaaattt aaaatttaac agttctaaaa tatcaagaac tatattttgt
      781 agcacttttt tattttatta ttgtttgaat atttgatagt tttcaatgca atttcaacat
      841 aaatactatg tattagtgta tactgttgct gaattaaagt atgataatct atttaataaa
      901 gtatgcagta aatgatttta atgtgtcttt atggtaaaat tactaataag taataaaatt
      961 aattaaaata tatggaggtg cttgtaatgt ttgctgtagg atttgttgtt ataattgcac
     1021 ttgccttttt catattaagt gtactattat ttaatggaaa agccagtatg ctactagcag
     1081 gttataactc tatgagtaag aaagaaaaag cacgatacga taaaaaaaaa ttatgtagaa
     1141 gttctagcat tgttactttt attgtctcta taatgctatt tattatggca tttttgggat
     1201 atagaataga gagtggtcaa atggacgaaa aaaaaatggt taccttttct ataatattta
     1261 taatagtcat actttccagt gtatttttta atatcctcta ctctaacaaa aaatgtaaaa
     1321 aataaatagt tgtaagttga gcagttaatt ataaaagatt gactgctttt tcctgtttat
     1381 tgactactct tattaaatat tttaacattt gaaaatctat atgaaaataa tgtatatagt
     1441 ataaacttct aataataatt ttatctttgt gtttaaagtc taccatatta taatttaata
     1501 taataacaga aaactactaa tgacaattaa gtaggctttg ataaaatata ataaaacaaa
     1561 aatagatgta caatgaaatt atatcttata tcaagtttat ttttattaat agcaaaaact
     1621 taaattagca taacatatga caaactcgct taaaa
//
LOCUS       DBGJFK010000151         1544 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.159, whole genome shotgun sequence.
ACCESSION   DBGJFK010000151 DBGJFK010000000
VERSION     DBGJFK010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1544
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.159"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            176..913
                     /locus_tag="ACOIAP_003563"
     CDS             176..913
                     /locus_tag="ACOIAP_003563"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2640430.1"
                     /translation="MKQNKYDDDKFFNKYSKMERSINGLAGAGEWHTFRKMLPNFKGK
                     RVLDLGCGFGWHCQHAVENGATSAVGIDISEKMLKEARNKTTFDNIKYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGDFVFSVEHPIFTAHGSQEWHCDK
                     DGNNLHWPVDRYFEEGLRKSNFLGEEVIKYHKTLTTYLNTLIKTGFEVLEIIEPQPEE
                     KLLDAIPGMKDELRRPMMLLVSAKKDK"
     gene            complement(1038..1529)
                     /locus_tag="ACOIAP_003564"
     CDS             complement(1038..1529)
                     /locus_tag="ACOIAP_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HGZ2640431.1"
                     /translation="MNNQQQEVYKKLDELNIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
BASE COUNT          559 a          181 c          224 g          580 t
ORIGIN      
        1 atcatttttt tgtttattat atataaagaa aaatttttta ataatataaa atatattcac
       61 ttatattatt aaaaaatttg tttatataaa cttttattat ttcatgtaaa agtgataaaa
      121 gtttatattt gatagagtat tgataaataa atatatttaa aatggaggga gctttatgaa
      181 acaaaataaa tatgatgatg ataaattttt taataaatac agtaaaatgg aacgttctat
      241 aaatggacta gcaggtgctg gagaatggca tacttttaga aaaatgttac ctaatttcaa
      301 gggaaaaaga gttttagatt taggatgtgg atttggatgg cattgtcaac atgcagttga
      361 gaatggggca acttctgctg ttggaattga tatttcagaa aaaatgctaa aagaagctag
      421 aaacaaaaca acatttgata atataaaata catatgtatg cctattgaag atattaattt
      481 tccaaaagat agttttgatg tggttattag ttctttagca tttcattata ttcaatcatt
      541 tgaagatata tgtaaaaata taagtaattg tctttcaaat aaaggtgatt ttgtattttc
      601 tgttgaacat cctatattta ctgcacatgg aagtcaggag tggcactgtg ataaggatgg
      661 taataatcta cactggccag tagatagata ttttgaagaa ggattacgta agtcaaattt
      721 tctaggagaa gaggttataa aatatcataa aacattaaca acttatttaa atactttaat
      781 taaaacagga tttgaagtat tagaaattat tgagcctcaa ccagaagaaa aactgctaga
      841 tgcaattcct ggtatgaaag atgagctacg tagacctatg atgctacttg tatctgcaaa
      901 aaaagataag taaacataaa taatcattat tgtagaaaat aattatacta atggaaatga
      961 ttatattaat agcattgatt acagcagtag taagaaggca aaagcattca ttgcttttgc
     1021 cattttttaa gttgcaatta tacttctacg tagtatattt cgtttccatt ttcttctata
     1081 agctttttca tatcttcaaa ttttaaaaat acagtagcag tattatcatt tggatgtata
     1141 cctattttat ccatttttaa taaatcctta tcaaatacaa cttttacaac agcttcttta
     1201 tcatttaata taccgaaagg agttacagct cccttagtaa gtttcaagta tttttgaagt
     1261 ctttcttctg atgcaaaact aagaggttta ctatcaattt gttgacgaat atcttttaaa
     1321 tctgcttttt tgtctttacc taatacaact aaaaaatgtt cttttccttt agcatcacga
     1381 agaaataaat tttttacaac aaattccata tgtaatgttt ttaattcttc catttcttca
     1441 attgtataaa ctggtggatg atttacagcc tcataaggta tgtttaattc atctaatttt
     1501 ttatatactt cttgttgttg attgttcatg atttcctcct atta
//
LOCUS       DBGJFK010000152         1249 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.160, whole genome shotgun sequence.
ACCESSION   DBGJFK010000152 DBGJFK010000000
VERSION     DBGJFK010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.160"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            9..92
                     /locus_tag="ACOIAP_003565"
     tRNA            9..92
                     /locus_tag="ACOIAP_003565"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Leu,seq:tag)
     gene            121..197
                     /locus_tag="ACOIAP_003566"
     tRNA            121..197
                     /locus_tag="ACOIAP_003566"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:155..157,aa:Arg,seq:tct)
     gene            205..280
                     /locus_tag="ACOIAP_003567"
     tRNA            205..280
                     /locus_tag="ACOIAP_003567"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:238..240,aa:Gln,seq:ttg)
     gene            369..457
                     /locus_tag="ACOIAP_003568"
     tRNA            369..457
                     /locus_tag="ACOIAP_003568"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Ser,seq:tga)
     gene            461..536
                     /locus_tag="ACOIAP_003569"
     tRNA            461..536
                     /locus_tag="ACOIAP_003569"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:494..496,aa:Phe,seq:gaa)
     gene            543..616
                     /locus_tag="ACOIAP_003570"
     tRNA            543..616
                     /locus_tag="ACOIAP_003570"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:577..579,aa:Met,seq:cat)
     gene            631..707
                     /locus_tag="ACOIAP_003571"
     tRNA            631..707
                     /locus_tag="ACOIAP_003571"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:665..667,aa:Ile,seq:cat)
     gene            731..807
                     /locus_tag="ACOIAP_003572"
     tRNA            731..807
                     /locus_tag="ACOIAP_003572"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:765..767,aa:Pro,seq:tgg)
     gene            815..891
                     /locus_tag="ACOIAP_003573"
     tRNA            815..891
                     /locus_tag="ACOIAP_003573"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:849..851,aa:His,seq:gtg)
     gene            900..975
                     /locus_tag="ACOIAP_003574"
     tRNA            900..975
                     /locus_tag="ACOIAP_003574"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:933..935,aa:Lys,seq:ttt)
     gene            983..1056
                     /locus_tag="ACOIAP_003575"
     tRNA            983..1056
                     /locus_tag="ACOIAP_003575"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1015..1017,aa:Cys,seq:gca)
     gene            1063..1137
                     /locus_tag="ACOIAP_003576"
     tRNA            1063..1137
                     /locus_tag="ACOIAP_003576"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1095..1097,aa:Asn,seq:gtt)
     gene            1144..1229
                     /locus_tag="ACOIAP_003577"
     tRNA            1144..1229
                     /locus_tag="ACOIAP_003577"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1178..1180,aa:Leu,seq:taa)
BASE COUNT          300 a          289 c          336 g          324 t
ORIGIN      
        1 aaaaatgcgc ggatgtggcg gaattggcag acgcactaga cttaggatct agcgccattg
       61 gcgtgggggt tcgactccct tcatccgcac catttttatt tgatatacat atataattgt
      121 gggtgcatag ctcagctgga tagagcaacg cccttctaag gcgtgtgtcc ggggttcgaa
      181 tccctgtgcg ctcaccacat atattgggga ttagccaagt cggtaaggca catgactttg
      241 actcatgtat gcgtaggttc gagtcctgca tccccagcca aatgatgtat ttactaaact
      301 atatttgagc tatttttatt ttaaggtagt tagattcaat tttagaataa gtttaagtat
      361 ccgaatatgg agaggtgtcc gagtggttta aggagctggt cttgaaaacc agtgacttcg
      421 aaaggggccg tgggttcgaa tcccaccctc tccgccaaat gcccagatag ctcagtcggt
      481 agagcagggg actgaaaatc cccgtgtcgg tggttcgatt ccgcctctgg gcaccagaat
      541 gtggcggtat agcttagttg gctagagcgt tcggttcata cccgaaaggt cataggttcg
      601 actcctatta ccgctactaa aatttaatgt gggccattag ctcagttggt tagagcgccc
      661 ggctcataac cggtaggtct ggggttcgag tccctgatgg cccaccacat taaattaatt
      721 aatataaatt cgaggtgtag cgcagtttgg tagcgcacat ggtttgggac catggggccg
      781 ggggttcgag tcccttcacc tcgaccaata taaggtgggt atagctcagt tggttagagc
      841 gccagattgt ggctctggag gtcgtgagtt cgactctcat tatccacccc aactcatatg
      901 gtctattagc tcagtcggta gagcacctga cttttaatca gggtgtcccg cgttcgagtc
      961 gcggatagat caccaaaaag gtggcgacat agccaagtgg taaggcagtg gactgcaact
     1021 ccttgatccc cagttcgaat ctgggtgtcg cctccaaaat attccaaggt agctcaacgg
     1081 tggagcaacc ggctgttaac cggtaggctg tgggttcgag ccccaccctt ggagccaaaa
     1141 aaagccgaag tggcggaact ggcagacgca caggacttaa aatcctgcgg gacttacctc
     1201 tcgtaccggt tcgattccgg tcttcggcac ttataaaaca atatcgcgg
//
LOCUS       DBGJFK010000153          832 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.162, whole genome shotgun sequence.
ACCESSION   DBGJFK010000153 DBGJFK010000000
VERSION     DBGJFK010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.162"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            14..104
                     /locus_tag="ACOIAP_003578"
     tRNA            14..104
                     /locus_tag="ACOIAP_003578"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Ser,seq:gct)
     gene            113..189
                     /locus_tag="ACOIAP_003579"
     tRNA            113..189
                     /locus_tag="ACOIAP_003579"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:147..149,aa:Pro,seq:tgg)
     gene            274..349
                     /locus_tag="ACOIAP_003580"
     tRNA            274..349
                     /locus_tag="ACOIAP_003580"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:307..309,aa:Trp,seq:cca)
     gene            410..486
                     /locus_tag="ACOIAP_003581"
     tRNA            410..486
                     /locus_tag="ACOIAP_003581"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Pro,seq:tgg)
     gene            493..569
                     /locus_tag="ACOIAP_003582"
     tRNA            493..569
                     /locus_tag="ACOIAP_003582"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:527..529,aa:Ile,seq:gat)
     gene            573..648
                     /locus_tag="ACOIAP_003583"
     tRNA            573..648
                     /locus_tag="ACOIAP_003583"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:606..608,aa:Phe,seq:gaa)
     gene            656..732
                     /locus_tag="ACOIAP_003584"
     tRNA            656..732
                     /locus_tag="ACOIAP_003584"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:690..692,aa:Met,seq:cat)
BASE COUNT          219 a          182 c          225 g          206 t
ORIGIN      
        1 aataactgaa tttggagaag tactcaagtg gctcaagagg atcccctgct aagggattag
       61 gctgggtaac cggtgcgagg gttcgaatcc ctccttctcc gccattcaaa aacgaggtgt
      121 agcgcagttt ggtagcgcac atggtttggg accatggggc cgggggttcg agtcccttca
      181 cctcgaccaa cttagctttt agttcggttg gttagagtgc ccaactcata accagagatt
      241 ctggggattg agtccatgaa ggttattctt cataggggtg tagctcagtt ggtagagcgt
      301 cggtctccaa aaccgtgcgc cgggggttcg agtccctcca cccctgccaa ataaaaagga
      361 cttgaaaaaa gttgggtttt agagtagtat aagatagtaa ataagatttc gaggtgtagc
      421 gcagtttggt agcgcacatg gtttgggacc atggggccgg gggttcgagt cccttcacct
      481 cgaccaagaa aagggcctat agctcaggtg gttagagcgc acgcctgata agcgtgaggt
      541 cgctggttcg agtccagcta ggcccaccat ttgcccagat agctcagtcg gtagagcagg
      601 ggactgaaaa tccccgtgtc ggtggttcga ttccgcctct gggcaccaga aatacggcgg
      661 tatagcttag ttggctagag cgttcggttc atacccgaaa ggtcataggt tcgactccta
      721 ttaccgctac catctaacta tatcaataaa gaactttgaa aattaaacag taggttaatt
      781 tataaacaag aaacaaacca taaagccaga tattttgata acaatagtat ct
//
LOCUS       DBGJFK010000154          818 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.163, whole genome shotgun sequence.
ACCESSION   DBGJFK010000154 DBGJFK010000000
VERSION     DBGJFK010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.163"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(61..474)
                     /locus_tag="ACOIAP_003585"
     CDS             complement(61..474)
                     /locus_tag="ACOIAP_003585"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGZ2640432.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
BASE COUNT          306 a          103 c           80 g          329 t
ORIGIN      
        1 aagtctgtag acgaagagca gaagttttaa gttaaaaaat attaaatgtg atttttatta
       61 ttatagtatt tttctaaaat aatatctctt tccagttaga ggataatttt caagtgaaaa
      121 tactttatgg tatccaaatt tctcataaaa tttaggtgct tgaaaactga atgtatctaa
      181 aaaaacatat ttacaacctc gttctttagc aattttttca gccttatata aaagttgact
      241 tccagtacct ttatatctaa gcttctcact aacccataag tattttatag aaagccaatt
      301 accatgagta acacctataa aacctgcaac aattttacct gctttatctc gaatatatat
      361 tcctaaatcc actggatttt tatcttcaag tctagcaaga ttatatttta ataatccttg
      421 aaaaatagta tcttcatctt gtttttctat tttttctgta atttctaatt ccatatttga
      481 actttctcct tgtataatct tttgcatatt ggtatttttt aataaaatca gtagaaagaa
      541 aatagtttaa cattattcta atagtcattt atgctaatgt caaactaata atacttattc
      601 ttaattttat attgttgata ttaaattttt aaaaataaaa atgtagttta agttatataa
      661 aaaaatcatc aataaattca gtaaacttaa attgttgaat attaaaataa gttaatttaa
      721 tacataaaaa ctattttaga tgttattcta ttgctatgtt caataatatc attagtagct
      781 caatttataa aatgactaaa ttatataaat aaagttag
//
LOCUS       DBGJFK010000155          813 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.164, whole genome shotgun sequence.
ACCESSION   DBGJFK010000155 DBGJFK010000000
VERSION     DBGJFK010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.164"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            100..216
                     /gene="rrf"
                     /locus_tag="ACOIAP_003586"
     rRNA            100..216
                     /gene="rrf"
                     /locus_tag="ACOIAP_003586"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            223..297
                     /locus_tag="ACOIAP_003587"
     tRNA            223..297
                     /locus_tag="ACOIAP_003587"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:255..257,aa:Asn,seq:gtt)
     gene            302..376
                     /locus_tag="ACOIAP_003588"
     tRNA            302..376
                     /locus_tag="ACOIAP_003588"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:335..337,aa:Glu,seq:ttc)
     gene            382..457
                     /locus_tag="ACOIAP_003589"
     tRNA            382..457
                     /locus_tag="ACOIAP_003589"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:415..417,aa:Val,seq:tac)
     gene            463..539
                     /locus_tag="ACOIAP_003590"
     tRNA            463..539
                     /locus_tag="ACOIAP_003590"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:497..499,aa:Asp,seq:gtc)
     gene            551..625
                     /locus_tag="ACOIAP_003591"
     tRNA            551..625
                     /locus_tag="ACOIAP_003591"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:583..585,aa:Thr,seq:tgt)
     gene            639..723
                     /locus_tag="ACOIAP_003592"
     tRNA            639..723
                     /locus_tag="ACOIAP_003592"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:673..675,aa:Tyr,seq:gta)
     gene            733..806
                     /locus_tag="ACOIAP_003593"
     tRNA            733..806
                     /locus_tag="ACOIAP_003593"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:765..767,aa:Gly,seq:tcc)
BASE COUNT          220 a          186 c          208 g          199 t
ORIGIN      
        1 tgtagttttt agagtgttaa ctctaaaaaa ttaaaaaaag tattgacaaa aaaagtaaaa
       61 aatgttaata ttatacttgt cctagcaaca agacaaaaat gtggttataa tagcagagaa
      121 gatacacctg ttcccattcc gaacacagaa gttaagttct ctagcgctga tggtacttgg
      181 tgggaaactg cctgggagag taggacatag ccacgtaaat gttccaaggt agctcaacgg
      241 tggagcaacc ggctgttaac cggtaggctg tgggttcgag ccccaccctt ggagccatta
      301 aggctcgttg gtcaagaggt taagacaccg ccctttcacg gcggtaacag gggttcaatt
      361 cccctacgag tcaccatttg tgggatcata gctcagctgg gagagcacct gccttacaag
      421 cagggggtca caggttcgag ccctgttggt cccaccattt gcggcctggt agttcagttg
      481 gttagaatgc cagcctgtca cgctggaggt cgagggttcg aaccccttcc aggtcgccaa
      541 aataaaaaat gctggtgtgg ctcaacggta gagcagctga cttgtaatca gcaggttgta
      601 ggttcgattc ctatcaccag ctccatgtaa attaatacgg aggatttccc gagcggccaa
      661 agggggcaga ctgtaaatct gttgtcatcg acttcggtgg ttcgaatcca ccatcctcca
      721 ccaattaaat atgcgggtgt agctcaatgg tagagttctg gccttccaag ccagctgtga
      781 gggttcgatc cccttcaccc gctccaaaga aag
//
LOCUS       DBGJFK010000156          744 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.165, whole genome shotgun sequence.
ACCESSION   DBGJFK010000156 DBGJFK010000000
VERSION     DBGJFK010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.165"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..>744
                     /locus_tag="ACOIAP_003594"
     CDS             <1..>744
                     /locus_tag="ACOIAP_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGZ2640433.1"
                     /translation="KKYYFNLNTAVAVTGWQTIDGKKYYFNTNTAEAATGWQTIDGKK
                     YYFNTNTSIASTGYTIINGKHFYFNTDGIMQIGVFKGPDGFEYFAPANTDANNIEGQA
                     ILYQNKFLTLNGKKYYFASDSKAVTGWRIINNKKYYFNPNNAIAATHLYTINNDKYYF
                     SYDGILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIV
                     YQNKFLTLNGKKYYFDNDSKAVTGWQTIDG"
BASE COUNT          279 a          100 c          116 g          249 t
ORIGIN      
        1 aaaaaatatt actttaatct taacactgct gttgcagtta ctggatggca aactattgat
       61 ggtaaaaaat attactttaa tactaacact gctgaagcag ctactggatg gcaaactatt
      121 gatggtaaaa aatattactt taatactaac acttctatag cttcaactgg ttatacaatt
      181 attaatggta aacattttta ttttaatact gatggtatta tgcagatagg agtgtttaaa
      241 ggacctgatg gatttgaata ctttgcacct gctaatacag atgctaacaa catagaaggt
      301 caagctatac tttaccaaaa taaattctta actttgaatg gtaaaaaata ttactttgct
      361 agtgactcaa aagcagttac tggatggaga attattaaca ataagaaata ttactttaat
      421 cctaataatg ctattgctgc gactcatcta tacactataa ataacgacaa gtattacttt
      481 agttatgatg ggattcttca aaatggatat attactattg aaagaaataa tttctatttt
      541 gatgctaata atgaatctaa aatggtaaca ggagtattta aaggacctaa tggatttgag
      601 tattttgcac ctgctaatac tcataataat aacatagaag gtcaggctat agtttaccag
      661 aacaaattct taactttgaa tggcaaaaaa tattattttg ataatgactc aaaagcagtt
      721 actggatggc aaactattga tggt
//
LOCUS       DBGJFK010000157          734 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.166, whole genome shotgun sequence.
ACCESSION   DBGJFK010000157 DBGJFK010000000
VERSION     DBGJFK010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.166"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            286..384
                     /locus_tag="ACOIAP_003595"
                     /pseudo
     CDS             286..384
                     /locus_tag="ACOIAP_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            386..>734
                     /locus_tag="ACOIAP_003596"
     CDS             386..>734
                     /locus_tag="ACOIAP_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2640434.1"
                     /translation="MVVVEKAYKFRMYPNKKQPELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLENAYEKFFKEKAGFPNF
                     KSKKINRFSYKTNF"
BASE COUNT          312 a           82 c          119 g          221 t
ORIGIN      
        1 tgaaggataa gatatagtct gtgcttacat gaaagtgtaa gaagttcata agagaactgc
       61 ataggtagta gcgaacctat gtgaacgaca acctcaaaaa tgataaaagt taagacttac
      121 agttcttata tatgttattt aaaattaaat ataaaacctt caaaatactt gttttaagta
      181 attgcatatt ttaatattat gataggtgat gaaaaatgga agttactcat ggtagaggat
      241 atgcatatag tatgtcaaat atagacatcc agtattatgg ggagacatct ttggaatcct
      301 agttatttcg ttgctactgt atcagaaaat acagaggagc agataagaaa atatattaat
      361 aatcacaaaa aacaagtaaa gtgaggtggt agtagtggaa aaagcttata agtttagaat
      421 gtatccaaat aaaaaacagc cagagttaat taacaaaact tttggatgtt gtagatttgt
      481 atataataaa tatcttgcta aaagaataga tgtttataaa aacgataaag aaacttttac
      541 ttataaacag tgtagttctg atttgaccaa cttaaaaaaa gaattaaagt ggctcaaaga
      601 acctgacaaa ttttcactac aaaacgcctt aaaagattta gaaaacgcat atgaaaaatt
      661 ctttaaagaa aaagcaggat ttcctaactt taaatcaaag aaaattaata gattttcata
      721 taaaactaac ttta
//
LOCUS       DBGJFK010000158          655 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.167, whole genome shotgun sequence.
ACCESSION   DBGJFK010000158 DBGJFK010000000
VERSION     DBGJFK010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.167"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..>655)
                     /locus_tag="ACOIAP_003597"
     rRNA            complement(<1..>655)
                     /locus_tag="ACOIAP_003597"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          143 a          205 c          149 g          158 t
ORIGIN      
        1 agttggcttc gcgcttagat gctttcagcg cttatccatt ccgtacatag ctacccagcc
       61 atgcccttgg cagaacaact ggtacaccag aggtacgtcc atcccggtcc tctcgtacta
      121 aggacaggtc ttctcaaatt tcctacgcct gcgacggata gggaccgaac tgtctcacga
      181 cgttctgaac ccagctcgcg taccacttta atgggcgaac agcccaaccc ttgggaccta
      241 ctacagcccc aggatgtgat gagccgacat cgaggtgcca aacctccccg tcgatgtgga
      301 ctcttggggg agataagcct gttatcccca gggtagcttt tatccgttga gcgatggccc
      361 ttccacgcag aaccaccgga tcactaagtc cgattttcat ccttgctcga cctgtatgtc
      421 ttgcaatcaa gctctctttt gcctttacac tctacgtacg atttccgacc gtactgagag
      481 aacctttgag cgcctccgtt accttttggg aggcgaccgc cccagtcaaa ctgcccacct
      541 gacagtgtcc caagaccaga ttcatggcct atggttagag tcccagtact acaagggtgg
      601 tatcccaagg atggctccgc caaaactggc gtcctggttt caaagcctcc cacct
//
LOCUS       DBGJFK010000159          606 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.169, whole genome shotgun sequence.
ACCESSION   DBGJFK010000159 DBGJFK010000000
VERSION     DBGJFK010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.169"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            complement(<1..332)
                     /locus_tag="ACOIAP_003598"
     CDS             complement(<1..332)
                     /locus_tag="ACOIAP_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGZ2640435.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKERPDADSITLKYKCYDMPLDTTLNYNQSTDSYEGTINYNKDPE
                     YLNVWELQG"
BASE COUNT          233 a           85 c           58 g          230 t
ORIGIN      
        1 ccttgtagtt cccaaacatt tagatattct gggtctttat tataattaat agttccctca
       61 tacgaatcag ttgattgatt gtagtttaga gttgtatcca atggcatatc atagcattta
      121 tattttaatg taatgctatc tgcatcaggc ctttctttaa acttaacact gacttttgaa
      181 gtactaccta aaacgatact ttttttctct aagtttatat ttaaatcagc attattctcc
      241 atagcattag attcagtagc aaatgccatt gtaggtgcga cgattgccat tgaaagaatc
      301 cctgttgtta ataattttgt atttcttctc atattaatct ccttatttaa cataaatttc
      361 tactttattt tttaaccttt taacttttga aaatatatca aagtgtattt acccaaaatt
      421 gtaaataagt acataaaata aaaaataaac ttctaaaaaa attataaaaa caaaaaataa
      481 aaaaattaaa tatattgaat atatttaatt atcttcacta tatcatttat tgccaaaaaa
      541 atctataaaa gacaaataaa aacatataat aattgtaggt ttattaaatt taatacaaca
      601 aaaaaa
//
LOCUS       DBGJFK010000160          577 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.170, whole genome shotgun sequence.
ACCESSION   DBGJFK010000160 DBGJFK010000000
VERSION     DBGJFK010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.170"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..>577
                     /locus_tag="ACOIAP_003599"
     rRNA            <1..>577
                     /locus_tag="ACOIAP_003599"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DBGJFK010000161          530 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.171, whole genome shotgun sequence.
ACCESSION   DBGJFK010000161 DBGJFK010000000
VERSION     DBGJFK010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.171"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            256..>530
                     /locus_tag="ACOIAP_003600"
     CDS             256..>530
                     /locus_tag="ACOIAP_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HGZ2640436.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDTTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIIVKHKDYLSFETKDFLSNIHD"
BASE COUNT          233 a           50 c           80 g          167 t
ORIGIN      
        1 aatattcctt gtgtgaaaat attgaaattt ttgttaaata gttttaatgt gtaataacat
       61 tttatactat tgtaattaaa tatgtaaaaa ggaaaatatt taaatagata tattttaaaa
      121 tctaactttt aatattgtaa aaaaattaga aaattaacaa aaaatacaaa aattcacatt
      181 tttttcataa agtgtttgac taaaaaattc acatgttgta gaattaaggt agcaagagtt
      241 ttgagggagg tgtaaatgat gataagaaaa ataccacaag cagaactaaa agtaatgaaa
      301 ttcatttgga aagtagatac tacagtgaca tcaaaagatg ttattgaagc tatggaacaa
      361 aaatatggct ggaaacaaac tactacactg acgcttttat ctaggctggt aaaaagaggg
      421 ttcttagatg ctcaaaaaat agacagatat acacattata caataatagt aaaacataaa
      481 gattatttaa gctttgagac aaaggatttc ctaagtaata tacatgatga
//
LOCUS       DBGJFK010000162          477 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.172, whole genome shotgun sequence.
ACCESSION   DBGJFK010000162 DBGJFK010000000
VERSION     DBGJFK010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.172"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
BASE COUNT          220 a           25 c           60 g          172 t
ORIGIN      
        1 gaaacaatta atttacagaa atttttaatt gttacaatat aaatatttag ataagttata
       61 aaatgttgat aaataattta gaaagtttat taatccaata ttatgtatgt ttatattaag
      121 taatcaagta gtctaaaaaa tgaaaaaggt ttaaaataag tattttaact aaatgtataa
      181 gagttaaatt tacatataag tatagattag atatataaga aataattatg taatatctat
      241 ctttgtaaaa aaatattaaa ttttgtaatt tgtggataaa tatgtttata atgtggataa
      301 tatttaatgt aataagttaa agcaatatga atcaactgtt tataatgtgg ataatattat
      361 aaatatatga ataattgtag tatttaaaaa caaaaaaagt taaaaaagtt gttgactcta
      421 aaagaaaaag ttggtatagt aatacttgtc ctcaagaaaa ggacaaacac ataaagc
//
LOCUS       DBGJFK010000163          455 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.173, whole genome shotgun sequence.
ACCESSION   DBGJFK010000163 DBGJFK010000000
VERSION     DBGJFK010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.173"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            150..266
                     /gene="rrf"
                     /locus_tag="ACOIAP_003601"
     rRNA            150..266
                     /gene="rrf"
                     /locus_tag="ACOIAP_003601"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            272..360
                     /locus_tag="ACOIAP_003602"
     tRNA            272..360
                     /locus_tag="ACOIAP_003602"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:306..308,aa:Leu,seq:taa)
     gene            372..448
                     /locus_tag="ACOIAP_003603"
     tRNA            372..448
                     /locus_tag="ACOIAP_003603"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:406..408,aa:Ile,seq:cat)
BASE COUNT          142 a           85 c          104 g          124 t
ORIGIN      
        1 tctatattgt taaacttgtc aaaatttata gatttttaat agttttataa ggcaaaaaat
       61 cgaataaaaa aagtattgac atattaagac aaagatgtta ttataatact tgtcttagaa
      121 aaaaagttaa atgaaaattt agacaataat ctggttataa tagcagagag gatacacctg
      181 ttcccattcc gaacacagaa gttaagctct ctagcgctga tggtacttgg tgggaagctg
      241 cctgggagag taggacatag ccaggtgatg tgccgaagtg gcggaactgg cagacgcaca
      301 ggacttaaaa tcctgcggga cttacctctc gtaccggttc gattccggtc ttcggcacca
      361 caaattattg tgggccatta gctcagttgg ttagagcgcc cggctcataa ccggtaggtc
      421 tggggttcga gtccctgatg gcccaccaca ataat
//
LOCUS       DBGJFK010000164          410 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.175, whole genome shotgun sequence.
ACCESSION   DBGJFK010000164 DBGJFK010000000
VERSION     DBGJFK010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.175"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
BASE COUNT          146 a           31 c           58 g          175 t
ORIGIN      
        1 tattattatg ctagacacat ttataacaat tgtttcttct attatagaaa tatggtcatg
       61 taaaaaagtt tttgattata cgagtcagac aaagactgac ttaaaaaaac taaatatgta
      121 tttcttcttt tctgtttttc ttattatttc ttttttatat ataaatatag gagctaatag
      181 tagaatcttg atatgtatat ttgtaatgtt cattttctat aagtctaact ataaagttaa
      241 tatatataaa tgtctagtga tatcattttt ttattggtta atattaatag gtataaatgg
      301 attaagtatg ttattagtag caacagtaag taatttggat aatatgaatg ttttacttag
      361 tggaagttta tatagatatg aagcaatatt cttgggaaag ttaatattag
//
LOCUS       DBGJFK010000165          361 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.denovo.177, whole genome shotgun sequence.
ACCESSION   DBGJFK010000165 DBGJFK010000000
VERSION     DBGJFK010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.denovo.177"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..>361
                     /locus_tag="ACOIAP_003604"
     CDS             <1..>361
                     /locus_tag="ACOIAP_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HGZ2640437.1"
                     /translation="NPKTLNKQDLENMGLNLKDYNVTQECIIEDITSRKDVNKYLRKT
                     SAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILL
                     VEKNNVPNSVKSELKRLN"
BASE COUNT          160 a           43 c           62 g           96 t
ORIGIN      
        1 aatcctaaaa ctttaaataa acaagaccta gaaaacatgg gattaaattt aaaagactat
       61 aatgtaacac aggaatgtat aattgaagat ataacttcta gaaaagatgt aaataaatat
      121 ttgagaaaaa cttctgcgcc tattacagaa cttacaggaa gcgatagata tgaaacagca
      181 gttaaaataa gtaaagaggg ttggaaaaat ggttcagata aggtagttat aataaatgga
      241 gatgtaagta tagatggtat tatatcaact ccactggcaa ctacatataa tgcgccaata
      301 cttttggttg aaaaaaataa tgtgcctaat agtgtaaaat cagaattaaa acgtctaaac
      361 c
//
LOCUS       DBGJFK010000166        15523 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.087, whole genome shotgun sequence.
ACCESSION   DBGJFK010000166 DBGJFK010000000
VERSION     DBGJFK010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.087"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            331..1326
                     /locus_tag="ACOIAP_003605"
     CDS             331..1326
                     /locus_tag="ACOIAP_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGZ2640438.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFIGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAIV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSEYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAVAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEELFNHFQKYKKITVSFSNETNIVFSKDCKVVEQT
                     NHKTSVVVPKERGNETIKWIFDRYDVKDVMIEEEDIVNIVERIYKKGSDEYYEQL"
     gene            1313..2167
                     /locus_tag="ACOIAP_003606"
     CDS             1313..2167
                     /locus_tag="ACOIAP_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640439.1"
                     /translation="MSNYNEASSNSSMFYKFKQSIRRYYEVAKINFKVQLIWRFDVVV
                     NMMFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLSGIDMSKSTSEEIC
                     NRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKINFAFTSNP
                     IQILISIFMIFLGLIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPLVLL
                     PETIVKVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYKRMR
                     TLFDGVGI"
     gene            2164..2958
                     /locus_tag="ACOIAP_003607"
     CDS             2164..2958
                     /locus_tag="ACOIAP_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HGZ2640440.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPIDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVIIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFSFTLFMWRFWKLGLRHYKSASS"
     gene            3241..4620
                     /locus_tag="ACOIAP_003608"
     CDS             3241..4620
                     /locus_tag="ACOIAP_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGZ2640441.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCHSYIFIILIFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGVLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLISEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNMLNINGIWLAVPSAEILTLFLTVFCIC
                     KHKNRYKYM"
     gene            4953..5783
                     /locus_tag="ACOIAP_003609"
     CDS             4953..5783
                     /locus_tag="ACOIAP_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640442.1"
                     /translation="MYIRDVTISNVKARVVNIKKQDSDTARLEYNKFLWRDFNMDTYF
                     NKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAISLCKIACPDVVILDIMLPD
                     IDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGDDYITKPFSPREIVFRVKAQ
                     LRRQQYQSIVPSDSSVIKIGDITIDIEGNRVYKDRKEIELTGREYHLLSYMAQNVNKI
                     IGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSNPKILITVKGLGYKLVNRID
                     "
     gene            complement(6060..7598)
                     /locus_tag="ACOIAP_003610"
     CDS             complement(6060..7598)
                     /locus_tag="ACOIAP_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGZ2640443.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVIPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQESAISGNEQHLIKASDYQEQLIANNFYSIDNEVNKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHEVLLLDEPTNFLDKEHVEWLSNYLNTFSGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKLHLREDYIRRYQSQQKKIEKEEAFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPGFTGKPNIKFSEIEISAQNALTVTNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPCISGDFQFSEQVKLAYYEQDL
                     KWENPTKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLFPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            8695..8895
                     /locus_tag="ACOIAP_003611"
     CDS             8695..8895
                     /locus_tag="ACOIAP_003611"
                     /inference="COORDINATES: protein motif:HMM:NF013209.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640444.1"
                     /translation="MPAVSEHIRKIEQLNLIQKYTIQINQEKIKYKLLAFVFINTDLS
                     KSMEEFKKTILEYDTALECHHI"
     gene            8880..9206
                     /locus_tag="ACOIAP_003612"
     CDS             8880..9206
                     /locus_tag="ACOIAP_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HGZ2640445.1"
                     /translation="MSSYLNLIREFNLKEKIIAFICVSALLIGKSCVLKNRKATTYHL
                     KNSKRQRQLSEFDVNVVNEPTVVNQNIITSYYTETAPHVAFKLLEMLISKKQLDEVKL
                     AMGFKL"
     gene            complement(9211..9534)
                     /locus_tag="ACOIAP_003613"
     CDS             complement(9211..9534)
                     /locus_tag="ACOIAP_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGZ2640446.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLEKL"
     gene            9686..10204
                     /locus_tag="ACOIAP_003614"
     CDS             9686..10204
                     /locus_tag="ACOIAP_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2640447.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLDKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGLNKLSKAANIYDAPLAILVCGDKEKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKVADSPDRHEKTR
                     VPLSEIVSYEIL"
     gene            complement(10395..11063)
                     /locus_tag="ACOIAP_003615"
     CDS             complement(10395..11063)
                     /locus_tag="ACOIAP_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HGZ2640448.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLILKNSTIKN
                     IIEKHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKIELPLKIDLANGSEHFYGIGAKEQILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKYYISSAFPDLKINS
                     IDIF"
     gene            11178..12593
                     /locus_tag="ACOIAP_003616"
     CDS             11178..12593
                     /locus_tag="ACOIAP_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGZ2640449.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILNGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNYIFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRAEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGVKVDDKGINTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKYATENGYYII
                     EDDYDSEFRYEGQPISSLYELNPNKVIYIGSFSKILSPAIRVGFILLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIEKILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHINQGT"
     gene            12792..13274
                     /locus_tag="ACOIAP_003617"
     CDS             12792..13274
                     /locus_tag="ACOIAP_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGZ2640450.1"
                     /translation="MKTNTDVIMEIIDYIEENLTENLNLDKIADIANYSKYHLHRMFT
                     NIVGCTIHQYIQRRRLTEAARQLIFTDKYIIDIAITAGYSTHQSFTLAFRNLYKESPQ
                     VYRNKDEFYPIQQRFVLNLNHQIQSEKYISYANMNCKQRIDEINSYLNFNINCEVKVA
                     "
     gene            13271..13855
                     /gene="clpP"
                     /locus_tag="ACOIAP_003618"
     CDS             13271..13855
                     /gene="clpP"
                     /locus_tag="ACOIAP_003618"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HGZ2640451.1"
                     /translation="MSLVPHVIEQTSQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSVTAGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRYALPNAEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDRIFSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            14158..15234
                     /locus_tag="ACOIAP_003619"
     CDS             14158..15234
                     /locus_tag="ACOIAP_003619"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGZ2640452.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGSPTLSYYRERLFKRSSNHKWVDPIHEVVPLSGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKVLEPRHQFYYSRELYYNAKYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPYIQLSVCYDRLGESNKAIYYHEK
                     TKEIKPNDSAVLHNENYFNKFKNS"
     gene            15313..>15523
                     /locus_tag="ACOIAP_003620"
     CDS             15313..>15523
                     /locus_tag="ACOIAP_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore surface glycoprotein BclB"
                     /protein_id="HGZ2640453.1"
                     /translation="MSRNKYFGPFDDNDYNNGYDKYDDCNSGRDDYNSCDCHHCCPPS
                     CVGPTGPMGPRGRTGPTGPTGPTGPG"
BASE COUNT         5719 a         1794 c         2414 g         5596 t
ORIGIN      
        1 tattctgtat aatcagaaat tttaagtgta tttttaatac atttaatttg tgtgtcttat
       61 tctgccttta tagataactg acatatgaca acaaatagta tttaaaatat atattacttt
      121 gttaaattat ggtgtagtag gttttaatct gctacacttt tattaatttt gtatagtatt
      181 attttgataa ctatgttgaa atagagagca ttaacttttc tagtccacag gagttttctg
      241 tttttgtgct gttaaatata agcatagaaa aaggcagata tatacctgtg gattttttta
      301 tataaattat gaaatatgga ggcgattaaa atgagcataa ttgaacttaa tgaactgact
      361 aaatcttata gaagatttga gaaaaaggca ggatttatag ggagtgtaaa gtctttattt
      421 aataggaaat atacagaaaa aacagctata tcatcatttg atttaaagat agaagaagga
      481 gaatttgttg gattaatagg tcaaaatgga gctggaaaaa ctactcttat taagatgtta
      541 actggtatta ttgcaccatc ttctggagaa atatctgtta tgggttatta ccctaataaa
      601 ttagaaaata attttaaaaa acaatatgct attgttatgg gtcaaaaaag tcaactattc
      661 tttgaattga caccagcaga tacgtttctt ttatttaaag aattatatga tatatctaat
      721 gaagaatata aaaaaaattt ggattacttt atcgaattat ttgaggtatc tgaatattta
      781 aatgttcaag ttaggacact ttccctagga gaaagaatga aaatggaact aatagtagcc
      841 cttctacata atcccaaaat attatttttg gatgaaccaa ctataggttt agatgctgta
      901 gcccaaaaac aaattaggta ttttctaaaa gaggtaaatg aaacaaaagg aactactatt
      961 attcttactt ctcattatat ggaagatatt aagagtctct gtagtagaag tattgttgta
     1021 gaaaatagcc gtaaaatata tgatggctct acagaggaac tatttaatca ttttcaaaaa
     1081 tataaaaaaa taacagttag tttttccaat gaaactaaca ttgtattttc aaaagattgt
     1141 aaagttgttg aacaaacaaa tcataagacc tcagtagttg tgccaaaaga aagaggaaat
     1201 gaaacgatta aatggatttt tgatagatat gatgttaaag atgtaatgat tgaagaagaa
     1261 gatatagtta atattgtaga gagaatatat aagaaaggaa gtgatgagta ttatgagcaa
     1321 ctataatgaa gcaagttcaa attcttcaat gttttataaa tttaaacaga gtattagaag
     1381 gtattatgaa gtagccaaaa ttaactttaa agtgcaactt atctggagat ttgatgtggt
     1441 agttaatatg atgtttacga ttgtaaaaat tttatttgct tatattttat ggaaagcaat
     1501 ttttggcgaa aataaaatag tctctggttt tacatttaac tctatgttgt cttactatat
     1561 aataagctca tttttatcag gtattgatat gtcgaagagt accagtgaag agatatgtaa
     1621 tcgagtaaaa ttaggcacat tttcaaagta catgattatt ccaattaatg ttcaaaatta
     1681 ttttattgct aaaaattttg gaatgacatg tttttatttt gtatttaata tgatttctgc
     1741 atttgtatgg atttttatat ttaaaataaa ttttgccttt acatcaaatc caattcaaat
     1801 attaatttca atttttatga tttttctagg acttattttt atgatgaaac tccacttctt
     1861 tattgggatt ttgtcattta aatttcttga gattagtttt tttagaatga taatagaaaa
     1921 tattgttgaa tttattacag gaacaatgat accacttgtg cttttaccag aaactatagt
     1981 aaaagttatg aaggtatttc cattttatta tacaacatat ttgccatcta tgttactaat
     2041 aggtagaaac agcaatgaag caatacaagg attaattatt ttagcattat gggttttatt
     2101 cttttctgta gtaaataaag ttatgtataa aagaatgaga acattatttg atggggtggg
     2161 tatatgatga aaaaaaattt gaaaataata tttatgttat taaaaatgaa attatcaaag
     2221 atgatggtat ttagatttga tttttttgga gcattttttg tagatagttc attatttata
     2281 ttacaacttc taatgtttaa tagtatatat tctcatgtag actcaatagg gggatggcaa
     2341 caaggagaga tgttaatatt tataggaact ttctcattaa taaatgcgat aaatatgacg
     2401 attttctttt ttggtattta tgatattcca cgaaaaattc aggaaggaga attagactac
     2461 tatattacaa aaccaataga cccactattt aggttaacat ttgaaaatat taatattggt
     2521 tcatcaccat taattttagc aagtatactt attgttttat atggaatctc tgaattaaac
     2581 tcagagataa ctttagtcat aataataata tatattttca tggtgctatt gatgacatta
     2641 cttttttatg atgtatgtat tatacttaga acagtttcat tttttgttat atcatcttct
     2701 gcgataatga gattagaaga taatttattg ccaatgaata tgaaaattcc tggtgtaata
     2761 tatgaaggtg tttttaaagt attattctat ttaatcttac catatggaat tatgtccaca
     2821 attccaactc aaattttggc tggaacaata actattaatg gattaatata ttcaatttta
     2881 attgtatttt cgtttacatt gtttatgtgg agattttgga agttaggtct gagacattat
     2941 aaaagtgcaa gtagttaata aattggcgaa aatagacaat ataattatat ataaatacgt
     3001 ttcacatgac actagactat gtaaacgagt atttacacta aaggcattga aagctataaa
     3061 atgattaaag taaggattta aaagttactt tagtataaat ataattgtgt aaaaaagcaa
     3121 gattaattaa aactatatcc aaataattag atataatttt tatgcagaaa ggaggtctgt
     3181 aaatgtctaa ttgtttggaa tatattttaa aaataattaa tgtacagaaa aataaacaaa
     3241 atgagtgatg tatattattc agaaaatcat gaacaagata atctttatga gcaagataat
     3301 ttactggcac aaagatttaa tttatttact ctattgaagt ttgcatttcc tactattttt
     3361 atgatgattt ttatgggatt gtatacaatc gtcgatacta tatttgtatc aagatttatt
     3421 aatacaaatg ctctatcagc aattaatatt gtatgtccaa ttattaatct tatagttgga
     3481 attggaacta tgcttgccac tggaggaagt gctattgtag cacgtaagat gggaaatggt
     3541 gatattgagg gagcaaataa agctttctct ttaatcgtat tatcaggagt tgtaattggg
     3601 gtaataatta ctggtatagg tattgtattt atggattata tcattatatg gttaggagca
     3661 agtgaagttt taattaaata ttgtcattca tatattttta ttatcttgat ttttgcttct
     3721 gcgaatatac tacaagtatt atttcaatgt ttatttgtaa cagctggaaa gcctcaattt
     3781 ggattatggc tagtgttagg tgcagggtgt gctaatataa ttcttgacta tgtgtttatt
     3841 gttctgttac aaatgggtat tagtggagca gcacttgcaa ctggagtagg atacctaatt
     3901 cctaccattt caggtatggt tttcttttca aaaaataaag gggtacttaa attttgtata
     3961 cccagactag ataaaagaat attatttgaa gcttgtttta atggttcatc tgaaatggtg
     4021 ggtcaactat caacagcagt tactactttt ttatttaatg ctatgatgat gaaattaatt
     4081 agtgaagatg gagttgcagc tattacaata attatttatt ctcaatttct tttaacttcg
     4141 ctttatatag gtttctcaat gggtgttgca ccaataataa gttataatta tggaagtgaa
     4201 aataatacac agttaaatca tgtttttaag atttgtatat tatttatttc agtggcatct
     4261 ttattggtat ttatcttttc tatatcatgt tcaccaatca ttgtagagat tttttctcaa
     4321 agaggaagcc gagtttatga aattgcaagg tctggatttt atatattttc ttttagtttt
     4381 attttttgtg gatataatat ttttacctca tctatgttta cagcattgtc aaatggcaag
     4441 gtgtctgcaa tattatcttt tctacgtaca tttggattta taactatagg tttattgata
     4501 ttgccaaata tgttaaatat aaatgggata tggttagcag taccaagtgc tgaaatttta
     4561 actttatttt taaccgtttt ttgtatatgt aagcataaga atagatataa atatatgtag
     4621 atattaaata aatagtttag gtagatattt tatgttttaa taagtaattc aattagtggt
     4681 agatagatac tattgaaaat taaagttata attgatataa agaattaata aaaataacat
     4741 ataaaagttt aaaaggggag ttgaacttaa agtttgatta gaaaaagtcg attttaagac
     4801 aactcctttt attttactat tgtattaatc tgtatctgta agtgtattag tctaatatta
     4861 taaactttgg atgaaattaa ttttctatag gttttaatgt atcatatact ttattttaag
     4921 gaaacgtatc ttaattttca tagtgattga atttgtatat tagagatgtt actattagta
     4981 atgtaaaagc aagagtagtg aatataaaaa aacaagatag tgatactgca agattagaat
     5041 ataataaatt tttatggaga gatttcaata tggatacata ttttaataaa aaaatattac
     5101 ttgttgatga tgaaaaagat atagtagatt taattgaaga agtacttata aatgatggtt
     5161 ttaaaaacat tattaaagct tataatggtt tagatgctat ttcgctgtgt aagatagcat
     5221 gtccagatgt tgtcattctt gatataatgt taccagatat agatggcata gaagtgtgta
     5281 aaaaaattcg agagttttca tactgttcta ttctttttct ctcatcaaaa aatgatgata
     5341 ttgacaaaat actaggtctt agtagtgggg gagatgacta tataacaaag ccattcagtc
     5401 caagagaaat tgtttttcga gttaaagcgc aattacgtag acaacagtat caaagtattg
     5461 taccatcaga tagttcagtt attaagatag gagatattac tattgatata gaaggaaacc
     5521 gtgtatataa agatagaaaa gagattgagt taactggaag ggagtatcat cttttaagct
     5581 acatggctca aaatgtaaat aaaattatag gaaaagaaag actctatgaa caagtatggg
     5641 gagtatacag tagtatttgt gacaatacaa ttatggtgca tatacgacat ataagagaaa
     5701 aaattgaaga taacccctca aatcctaaaa tacttataac agttaaaggt ctaggatata
     5761 aacttgtgaa tagaatcgat tagaatagat cttagtatca atgaaggtgt ctcaaattca
     5821 atttgttagt taatgagaca ttcttttttg tgtgaaatca aatgtatttt tgttatatca
     5881 ataatgaaga agaggcttat ctctattttg agatagcctc attaaattta taccgtggta
     5941 atgcacttta tgctctaata aatatttatt ttttagttta cttgcagtga aacattaact
     6001 aggagattaa aatttgcatt gaaatgctaa ttaaacaata tcgcatattg tatataaacc
     6061 tacactaatt gtttttctat attaaatact ttgtcaatcc agcctttata aaatttttct
     6121 tcatgggaaa ctagaattat acttcctcta aactgtttca aagcattttg taaagcatcc
     6181 tttgtttctg catcaaagtg gttagttggc tcatctaaaa tcaaaaaatt acaagggaat
     6241 aacatcatac aacataattt taccttagat tgttcaccac cacttaatgt agatacactc
     6301 cttgaaacat gttcttcctt tacgccacat ctggctagat gacgtctaat ctcttttgta
     6361 ttcaatttcg gatatttatc tgctactatt tgaagcggtg ttttagtagg attttcccat
     6421 tttaaatctt gctcataata agcaagtttc acttgttcag aaaactggaa atctccagaa
     6481 atacaaggaa tatctttaac taatgttttt aacaaagtag atttaccaat tccattaaaa
     6541 cccgttataa ctattttttg acccccatca acagagaaat ttaattttgg aagcaaagaa
     6601 tagtagtagc caacttcaag atttgttact gtaagagcat tttgagcaga tatttcaatt
     6661 tctgaaaatt ttatatttgg ttttcctgta aaaccaggag gagctattct ttctatttta
     6721 tccaattgtt tttgtcttcc tcttgcaatt tttgaattta ctccagcttt gtttttacgt
     6781 ataaatgcct cttctttttc tattttcttt tgttgtgatt gatatcttct aatataatcc
     6841 tctcttaaat gtaatttttg tttaaggaac tctgaatatt ttccatgata tttcttaatc
     6901 ataccaaatt ctatatcaag aatacctgta gaaattttct ctaaaaagtc aaaatcgtga
     6961 gaaactacaa taaatgctcc actaaatgta tttaaataat ttgagagcca ttcaacgtgt
     7021 tctttatcta aaaagtttgt tggttcgtct aataataaaa cctcatggtt agaaagtagc
     7081 aattttgcta aaattacctt tgccctttgc ccaccgctaa gctccccaac aacacgattc
     7141 attcctattg aatctaatcc aagaccattt gctattttat ttacttcatt atctatagaa
     7201 tagaaattat ttgctattaa ttgttcctga taatctgatg ctttgattag atgttgctca
     7261 tttccagata tagcactttc ttgatagagt aaattcatct ccttttctat tttataaagt
     7321 tcttcaaatg cagtgtgtaa atagagtgat attgttgtat ctctattgat ttctgcatat
     7381 tggtctaaat ggcctatatt gatattaggt tgccacttga tttctcctga atctggaata
     7441 acttctccca ataaaatttt aattaatgta cttttgcctg taccattttg gccaactaca
     7501 cctatatgtt cacctttgaa taaatcaaag ttagctttct catacagtga tttatccata
     7561 aaacattgtg ataaattagt tacttttaat aaactcataa ttcaaactcc ttttctttta
     7621 ttaaaaaatt tatggaaata aaaaaagcag aggaatgaca ttataaaatg ccgacctctg
     7681 cttttggaaa aacaaaaggt catagacaag cattgttgtc tatgaccaga aaatctatat
     7741 tatctatcgg caaataggta attttaaata agcatagccc aaaaactaca ctaaacctat
     7801 atttgccgat gaagatagaa agctttaagc tttcagatta acctctacac aacgcttcat
     7861 cgtatacatt tgtgtagagt taagttttct aacaagttta actaattcta tataaatcat
     7921 aattattcac atcctaatct tagtattaat tctagtttat ctatatttaa attgtacttt
     7981 tgtactttgt atattgcctt atttacttaa aatatatttt attaattata gcttaaatca
     8041 tgttatcata atacttagtt atagtcaata agaaagttat atttgctaca taacctatta
     8101 atttagtaaa tctatcatta caaagttatt tgaagactca ccaccaataa aattttataa
     8161 tctattaaaa aattaagatt acgagattta taattttgat acaggtatac tatctttatt
     8221 aaatattgca acatgtagaa gtagatggat aatattatta aattttcaat gatatgctaa
     8281 tgtacatata taattattag aaataaaaat ataatagtat gaaagtaact gatataataa
     8341 ctaaatgatt aaacatatag taaaagtact tcataaatta tggagtatct tttattgtcg
     8401 caaaaataag caatatatta tacaaaataa aaacattaat tcaacttaaa taattttaag
     8461 tgtaatatgt attttgatta aataagctaa aattctaaga aaaaataata tatttgtatt
     8521 aagttttatt gaaataatta aaattattta cttaatgtaa attgttagct taaattatat
     8581 taaataatta aggcggtgag tgggtctgga tgagatagat ttaaaaataa ttaattctct
     8641 aagaaagaat ggtaggtttc aacttctgaa ataagcagaa aaattaattt atcaatacca
     8701 gcagtctcag agcatataag gaaaattgag caattaaatt taattcaaaa gtacactatt
     8761 caaattaatc aggaaaaaat aaaatataag cttttggctt ttgtatttat caatacggat
     8821 ttatctaaaa gtatggaaga atttaagaaa actatattgg aatatgatac tgcattagaa
     8881 tgtcatcata tttaaatcta ataagggagt ttaatttaaa agaaaaaata atcgctttta
     8941 tttgtgtgtc agcattgctg attggaaaaa gttgtgtttt aaaaaatcgt aaagctacta
     9001 catatcattt gaaaaatagt aaaagacaaa gacagttaag tgagtttgat gtaaatgtag
     9061 ttaatgaacc aactgttgta aatcaaaaca ttataacctc atattataca gaaacagctc
     9121 cacatgtagc ttttaagctt ttagaaatgt tgatatctaa aaaacaactg gatgaagtta
     9181 aattagctat gggatttaaa ctgtaatagt ttagagcttt tccaagtaat cagaacccca
     9241 gtcgcacatg gaatctaaaa ttggaataat actctttcca aaatcagata gtgagtattc
     9301 tacttttgga ggaacaacag gataaaccac tcttatgatt aaaccatctg attctaattc
     9361 acgtaattgt tgagttaaca ttttaggtgt tgccttaggg attaattttt ttaattcatt
     9421 gaacctcaat atagtgtctt taagatgcca aagtataagt gtcttatatt taccaccaat
     9481 caatgcaagt gttgcttcta ttgggcaact gtaattatct aaacattttt tcatttttgg
     9541 actcctttat ttattttaaa gtatcttttt aggtactata ttacaaaaaa gtgcattatt
     9601 gtaatatatt accatagtgc taaaattata gcataggtta aataaatcat caacttagtc
     9661 taataaaaca ataggaggta aataaatgaa tttcgttgaa cttgcaaaaa aaagatattc
     9721 ttgccgtaat tatcaagata gaaaggttga aaaagaaaaa cttgataagg ttttagatgt
     9781 tgcaagaata gctccaactg gtggtaatcg tcaacctcaa agattgattg ttattcagga
     9841 aaaagagggt ctaaataaac tttccaaggc tgccaatata tatgatgctc cattagcaat
     9901 tcttgtgtgt ggagataaag agaaggtttg gacaagacct tttgatggga agcaacttac
     9961 agatattgat acaagtatag ttacagacca tatgatgcta caagcaactg aacttggatt
    10021 ggcaagtgtt tgggtatgct attttaatcc agatataatt agagaagagt ttagtttgcc
    10081 agataatcta gaaccaataa atattttatt gatgggatat gaatctaagg tagcagatag
    10141 cccagataga catgaaaaaa ctcgtgttcc tttaagtgaa attgtttctt atgaaattct
    10201 ttaattataa aattaagtta ttcataggtt aaatgtaaca aagtgtttat tataaataaa
    10261 actcaaaata aataatatcc ttagataaat aatatctata taattaattt tagtgaagta
    10321 tatctagttt aactagaata tatacttcac taatttattt gttcaaaata tttgtgagga
    10381 ttttaatata ttaactaaaa tatatcaatt gaattaattt ttaaatctgg aaaagcactt
    10441 gaaatatagt attttatgtc atttaaatgg tcttgaattt gtttttctga tattttatca
    10501 ggtccatata caaaatacat aatattttta gtatcttttg ttatagctgt tcgattatca
    10561 ggtccattaa gaatgctaga taatatacca atattatccg ataaaaataa atcatctttt
    10621 gtcaaaatct gttctttagc acctatacca taaaaatgtt cacttccatt tgctaagtct
    10681 attttcaaag gtaattctat tttatcaagg tcatgacctg ctgttagaag aagatttttc
    10741 aattctgcta aaaacattga ctcaattgtt acacctacat ctgggatacc ttttgatttt
    10801 aatagaatag attctaattg aagcaataca gggtaagttt tcttgaattt tttgtaatac
    10861 tttatataac ttgaaacagg ctctgtttta attttttctt tacgattgta ttctggatgt
    10921 ttttctataa tatttttaat tgtagagttt ttaagaatta aaaaattttc tttattaggt
    10981 tttgaatgtg taatatttat aaccataact ccaaatttaa tattgggata aatttctttc
    11041 actttatgtg atatttctaa cataatatag actccttttt attttttgtt ttatgatata
    11101 atcttagcaa gttaaaagta gattttgtag ttccattttt atagtaattt tatagaacca
    11161 cttttggagg tattagaatg tggattacga ttaatagaaa tagtaatata tcattatcaa
    11221 gacaaattta ttgtgagata aaagatatga ttctgaatgg aagcttaaag tttgagcaaa
    11281 aattgccatc atctaggact ttatcaaaag aactatctgt atctcgtaat acagttttag
    11341 atgcatataa tcaattaatt gcagaaggat atttggaaac aaggaatgga tatggaacaa
    11401 ttgtagctaa aggaatatca gggcataaag ttgattttaa gttaaattat atttttagag
    11461 atgaaaaaga tttacatact aataaacaaa aaaattatat agattttcgt tcaggagttc
    11521 cagaattaaa actatttcca cgcaaagaac tttcaaagct atataaacaa atactgtatg
    11581 atttatctga ttcggatttc agatatggaa gtacagctgg tgtatgggtt ttaagagcgg
    11641 aaatatctaa gtatttattt cgtactagag gaattagatg taatcccaaa aacattatga
    11701 ttgtttctgg ttcaacacaa ggtttatctt taatttcaca gcttttatac aaaagtaata
    11761 aaaaggttgc tgtagaagac cctattcata aaggcttatt aaaggttatt tcatctattg
    11821 gatattcagt tgttggagtt aaagtagatg ataagggaat aaataccaac ttaataaaat
    11881 caataaaggg gatttctttt gtttatacta caccttctca tcaataccca ttaggaggga
    11941 ttttacctat tcaaagaaga ctggagctta ttaaatatgc aacggagaat ggttactata
    12001 taattgaaga tgattatgat agtgaattta gatatgaggg tcaaccaatt agttctcttt
    12061 atgaacttaa cccaaataaa gtaatttaca taggttcttt tagtaaaata ttatctccag
    12121 ccattcgtgt tggatttata ttattaccag acaatatttt agaaagctat aaaaccttaa
    12181 aaatgtactc tgatgttcat acagaaacaa tattacaaca tgtattagct gaatttattg
    12241 gaaatggagg tttagagaag tacatattta gaatgaagaa gttgtataat agaaaacgta
    12301 agtacctcat aaaagtttta aacacggaat ttaaaaatga atttaaaata aaaggtgaag
    12361 cagcagggct tcatatagtt gctcatttct ataatgttaa atttacggaa agtttaattc
    12421 ataaaatttt tgaagcaggc ataaaagttt atcctataca acaatatgca attgagaaaa
    12481 tattagaata tgaccatgaa attatactag gttatgctca tcttagtttt gatgaaattg
    12541 aaaaaggtgt aaaaatactc agcaaaataa tacatataaa tcaaggtaca tagataaaac
    12601 atatagcaat ctacatataa tagatgcaat gaagtttaaa ctttaaaaga aatatatatt
    12661 aatatttttg tataaaaata cctgatattg tgttatcgat actttgttgc tatacactaa
    12721 attaagatag caatttatat taagaaaaaa ctttttgcat aggttataat acttaaaagg
    12781 agaggataga gttgaaaaca aatacagatg ttattatgga gataattgat tatatagaag
    12841 aaaatcttac agaaaatcta aatttagata aaatagctga tattgctaat tattcaaaat
    12901 accatttaca cagaatgttt acaaacattg taggatgtac tattcatcaa tacatccaga
    12961 ggaggagact cactgaagca gctagacagc ttatatttac agacaaatat attatagaca
    13021 tagctattac agcaggatat tctacacatc aatcttttac actagcattt agaaatttat
    13081 ataaagaatc tccacaagta tatagaaata aagatgaatt ttatcctatt caacagagat
    13141 ttgttttaaa tctaaatcat cagattcaaa gcgaaaaata tatttcttat gcaaatatga
    13201 attgtaaaca aagaatagat gaaattaatt cttatcttaa ctttaatatt aattgtgagg
    13261 tgaaagtagc atgagtttag taccacatgt aattgaacaa acaagtcaag gggaaaggtc
    13321 ttatgatata tattcaaaat tattaaaaga tagaattata tttataggag aagaaattaa
    13381 tgatgctatt gcaagtttag tagtagctca attactgttt ttagaatcag aagacccaga
    13441 ttcagatata attatatata taaatagccc tggtggctct gttacagcag ggtttgctat
    13501 atatgatact atgaattatg tcagatgtga tgtatcgact atttgtattg gtatggctgc
    13561 aagtatgagt gcttttttac ttgcaggagg aacacatgga aaaagatatg ctttacctaa
    13621 tgcagagatt atgattcacc agccaatggg aggagctaaa ggtcaagcaa cagatgtaaa
    13681 aatagctgta gataatatat tgaaaataaa agaacgatta gatagaattt tttctgaaaa
    13741 tacaggtaaa tcaatagaag atattagaag agatacagat agagataatt ttatgactgc
    13801 actagaagct aaagagtatg gactgattga ttatataatg aataggaatg aataaagtat
    13861 catattaaaa tatctgtttt ataaatatat atagaatatt aaataagagt gtctcaaagt
    13921 gaacttttta gtttatggga tgctcttttt tgtatgaaat taaatatagt tttattattt
    13981 caataactag tatcaaattt caagtttaat aaattctacc ataaaaatac ataaaagata
    14041 aggtttttta gtaactttct gtcgtcaaaa gtttttataa atttaataac aaaacaagag
    14101 aaaataccat atattactta tgtctgcaat atatagaaga caaaggagtt gtacattatg
    14161 attacaataa gtttgtgcat gattgttaaa aatgaggaag aagttatagg cagatgctta
    14221 gaatgtgtaa aggatatagt agacgaaatt ataattgtag atactggttc tacagattcc
    14281 acaaaagaaa tagtctcaaa atatacagac atggtgtacg atttcgaatg gatagatgat
    14341 ttctctgctg caagaaattt ttcattttct aaagcttcta aagactatac gatgtggctt
    14401 gatgcagatg acataatttt agaagctgat agagaaaaat tattaaagat taaagaaagc
    14461 ttggatactt ccattgatat tgttatggca aaatacaatg tatcctttga tgaaaatggt
    14521 agcccaactc tctcgtatta tagagaacga ttgtttaaaa gaagttctaa tcataaatgg
    14581 gttgacccta ttcatgaagt agtacctctt tctggagagg tattttattc tgacattgca
    14641 atatctcata aaaagcttca tagacaagac cctctaagaa atcttagaat ttttgaaaaa
    14701 atgatttcag aaggaaaagt attggagcca agacaccaat tttattactc tagagagttg
    14761 tactataatg ctaagtataa agaagcaata gaaggtttta ctaagttttt agactcatca
    14821 agaggatgga ttgaggattg tatcagtgct tgcagagatt tagccacatg ttattactta
    14881 attaatgatg aaaagagtgc cttatattct ttgtttagaa gttttgaatt tgatgagcca
    14941 agagcagaaa tttgttgtga cataggaaag catatgtttg atagacaaaa atataaagaa
    15001 gctatttttt ggtataaggt agcactaaca agagataaga atgatactaa tggaggtttt
    15061 aagtcaaatg attgttatgg atatatacca tatatacaat taagtgtctg ttatgacagg
    15121 ctaggagaat caaataaagc tatttattat catgaaaaaa caaaagaaat caaacctaat
    15181 gatagtgctg ttttgcacaa tgaaaattat tttaataaat ttaaaaatag ttgataggtc
    15241 acaataatac taaatttgac atattatata tagagcttag aagctcaaat atatcaggag
    15301 gtgcttttaa taatgagtag aaataaatat tttggaccat ttgatgataa tgattacaac
    15361 aatggctatg ataaatacga tgattgtaac agtggtcgtg atgattataa tagctgtgat
    15421 tgtcatcatt gctgtccgcc atcatgtgta ggtccaacag gtccaatggg tccaagaggt
    15481 agaacaggcc caacaggccc aacgggtcca acaggaccag gag
//
LOCUS       DBGJFK010000167        15268 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.089, whole genome shotgun sequence.
ACCESSION   DBGJFK010000167 DBGJFK010000000
VERSION     DBGJFK010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15268
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.089"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            380..1177
                     /locus_tag="ACOIAP_003621"
     CDS             380..1177
                     /locus_tag="ACOIAP_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2640454.1"
                     /translation="MALPGTPGQRISDLCNGNHITQKELAEKIGVSASQLSRIVSGET
                     RTVSSDILIGVAKEFKVSTDYILGLSTVSVRKSYDISELGLSEGAVRGLVTGAVDVQI
                     LNRLLEHRNFPKLIDLIRIYFQDTAAKGITARNQLIEMATASLSDLMKEHPEHRAEAK
                     QDLQLLNAQKMGEHEAEIEKIKNVFLAILRDIKKDIDNGEQPGEAVTAAMFQAMRDAL
                     AEQKQKPLSIDDVAAMVAGQIGQLTPMDEETADLFKQLAKKMMKGIE"
     gene            1202..1972
                     /locus_tag="ACOIAP_003622"
     CDS             1202..1972
                     /locus_tag="ACOIAP_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGZ2640455.1"
                     /translation="MPLVKHDYPVLEYDTASKAVFQPGNGKKCFPAKAVFAFLGDEVE
                     NYAHTHDGIQIDEFESATRRYPIYECLYNQEKICLCPAPVGSAAAVQVLEYLIAGGVT
                     KIISVGSCGVLEDIPENRFLIPVSALRDEGTSYHYLPPSREVEISKAGINAIESALSQ
                     KNIPYWEVKTWTTDGFYRETVEMVQYRKEEGCQVVEMECSALAACAKFRKVTWAMLLF
                     SADTLADPHKYQEREWGKTSISIALELALDAVLSVVEE"
     gene            1997..2773
                     /gene="ant(9)"
                     /locus_tag="ACOIAP_003623"
     CDS             1997..2773
                     /gene="ant(9)"
                     /locus_tag="ACOIAP_003623"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)"
                     /protein_id="HGZ2640456.1"
                     /translation="MNINEFPQQVNQVISIAETILQGQILGIYLYGSATMNGLRPDSD
                     IDILIITKQELSNSIRADLTKQLLKISGSVGCIEKRPLEVTIINQSDIVPLQFPPKCQ
                     YMYGEWLRGEMEAGEYPQACNDPDIMILLWQARKNSITLKGAESKELIPAIPFHEIKK
                     AIRFSLPGLISSFKGDERNVLLTLSRMWFTLVTEEITTKDVAAKWVILKLPERFSPLL
                     TTAKEAYLGNLSDEWETVEKEAMALVEYMKKQIEELLRTE"
     gene            2923..3072
                     /locus_tag="ACOIAP_003624"
                     /pseudo
     CDS             2923..3072
                     /locus_tag="ACOIAP_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            3151..4188
                     /locus_tag="ACOIAP_003625"
     CDS             3151..4188
                     /locus_tag="ACOIAP_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595-like element ISSag10 family transposase"
                     /protein_id="HGZ2640457.1"
                     /translation="MPTIKDALDIIGKLTVAEQESLKTMLLSPAFVKSLNIEDFVAKE
                     RFANGRVCPLCGCIHVVRNGHRKDGTQRYVCKDCGKSFVIATNSIVSGTRKDLSVWEQ
                     YIDCMMNGLSIRKTAVACGIHRNTAFLWRHKILDALQNMADDVTLDGIIEADETFFAI
                     SYKGNHSKSKTFAMPRKAHKRGHSTHIRGLSQEKVCVPCAVNRNGLSISKITNTGRVS
                     TRDLHHIYDGRIKTNSTLVTDKMNSYVRFTNANGIDLVQLKTGKAKKGIYNIQHINSY
                     HSQLKRFMRGFNGVSTKYLNNYLVWNNLVNYAKESDMEKRNIFLTFVLATLKTAKCRD
                     LSNRPAVPLVA"
     gene            4212..4706
                     /gene="lnu(C)"
                     /locus_tag="ACOIAP_003626"
     CDS             4212..4706
                     /gene="lnu(C)"
                     /locus_tag="ACOIAP_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(C)"
                     /protein_id="HGZ2640458.1"
                     /translation="MVNITDVKQILQFAIDAEIKVFLDGGWGVDALLGYQSRAHNDID
                     IFVEKNDYQNFIEIMKANGFYEIKMEYTTLNHTVWEDLKNRIIDLHCFEYTDEGEILY
                     DGDCFPVETFSGKGRIEEIEVSCIEPYSQVMFHLGYEFDENDAHDVKLLCETLHIEIP
                     NEYR"
     gene            4788..5522
                     /locus_tag="ACOIAP_003627"
                     /pseudo
     CDS             4788..5522
                     /locus_tag="ACOIAP_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5968..6405
                     /locus_tag="ACOIAP_003628"
     CDS             5968..6405
                     /locus_tag="ACOIAP_003628"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640459.1"
                     /translation="MPKGAPLWKPPQEKAVRYPSTGRIPPFVVSSPFHGLFSPFVKFG
                     VANFVGTSNCIEKEDYVNFNIEKETKPYIYKRPEEMVLLQNTNQSGFIKVKVESKNFL
                     GAILEYTVSNNGKKYQVTELNRLNNSNKLNVGDMAYLGVLQGN"
     gene            6407..8101
                     /locus_tag="ACOIAP_003629"
     CDS             6407..8101
                     /locus_tag="ACOIAP_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640460.1"
                     /translation="MIKKIKRSKFTPKNVISIILYSILFWILIGYIIIPIGNTFTQAF
                     QGKGGYSFEVFKEYFSNTNNLKVVSNTIILGFGSVLVCGIMGISLALYMTFVCDKHKK
                     IIHILLLSPMMIPGVIMVIACIQLYGESGIVTKSIEILLSFIKKPYDFSGLKGVLFVV
                     AYTQYVYFYLNVYVALKYVDYSTVEAAKGMGASKIRVFFDVIWPVITPAIITSTIITF
                     ASGISSFSAPNLIGGGFKVLSTQIVRSKANNHMDIASVQVIILLLMGISFMILLQYYG
                     KKYGVVASLKSQGYKVHNRKKDLFTFVCKVIIEIQIVMIMLPIVTIVYLSFVSTHSIM
                     TTIFPRDFTLENYQMIFQKSRVLQPILNSLKMSLMAVVIGLIITIPVSYLVIKKDTTY
                     NRLAKFIIMLPWSMPASAIAVNLINTFNQKSIFAFNESLIGGFYIVPIAYTIYALPLL
                     FSSNEVAMKSINLGLEESSRSLGAGRIKTFYNVIVPNMMPGIISGAILVFIRTIGEYT
                     MSALLYGVYNRPISISIVTNMQEFKIGVSMAYGVLVIGICYIALGIIFKLDRKRFT"
     gene            8653..9531
                     /locus_tag="ACOIAP_003630"
     CDS             8653..9531
                     /locus_tag="ACOIAP_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGZ2640461.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREVVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FIEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCREVLEKNSSLYEPDTIYPPCIDAAREVIEFKMN
                     LFNTIDKLKCFYKNKN"
     gene            9567..11462
                     /locus_tag="ACOIAP_003631"
     CDS             9567..11462
                     /locus_tag="ACOIAP_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGZ2640462.1"
                     /translation="MIGQILRSDCIVLDKQLQTKKDVIDYMANHLYHGNYINDKEKFI
                     VDINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDKEITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMDENLLKHLLSAETPYEILSIFNNKAVESGDSSDNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQMSRFIGKKVLQKKVADAKNVSLAKNLIINAENGMAKEIKPGGRTLEDSK
                     EILQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFSTG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSSPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVEVLGA"
     gene            11729..13636
                     /locus_tag="ACOIAP_003632"
     CDS             11729..13636
                     /locus_tag="ACOIAP_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGZ2640463.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKIIE
                     KYLETFNIKIDIKRGYGILIESLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISKLTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTISQPYYINLITHILICLKRIEEGNQIESQEEREVSVDNLDELVYQNVTALIGKIEN
                     RYGVKITKDEIMYIYIFLVSSGFSSESNNSYNDESYRLSESEKFSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSNRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDISNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVMQMESLIGVDLGSKYKSISLGKDLNIYIHNQSKLN
                     KGIMNVNNINRTIDIYLETSNQSFLKNILMEISNLYRQKSYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            13626..14075
                     /locus_tag="ACOIAP_003633"
     CDS             13626..14075
                     /locus_tag="ACOIAP_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGZ2640464.1"
                     /translation="MEIREILSEESIILDLKSTTKEGIIQELVDKLYDTGSIDLKSKF
                     IKALKRREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGIDWPSIDGLPVKVIIM
                     FAMPQSGDNEDMTLISKIAYILGGKDISERLLNANTKKEILDIFYEV"
     gene            14175..14330
                     /locus_tag="ACOIAP_003634"
     CDS             14175..14330
                     /locus_tag="ACOIAP_003634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640465.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFIWK"
     gene            14493..>15268
                     /gene="licT"
                     /locus_tag="ACOIAP_003635"
     CDS             14493..>15268
                     /gene="licT"
                     /locus_tag="ACOIAP_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGZ2640466.1"
                     /translation="MIINKILNNNVVITLDDNDEEIIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEVSNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGVKLPEDEAGFIAFHI
                     VNAQLSEGHTFASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLN
                     NAHEGGTDKELLSIIKSKYNKEFECVVKIKDFIKKQYNYI"
BASE COUNT         5551 a         2108 c         3019 g         4590 t
ORIGIN      
        1 agcggcaaaa ctcactcgct ccgctgctcc tcctctcccc acaaagccat gcggctttgc
       61 gggggccccg acaatagcgg cgtattccgg cgttggcacg ctccccgcag cttcgggacg
      121 ttttgtcccg aagtgacctc tggacaaagt gtccaaaagt ccggctcctg gcggtgcttc
      181 cccagccgtg gtattctctt ttcggacggt cattctgttt tcaaggtgct gtccatcgat
      241 gaactaccct aagtctacac gaaaaaaatg caaatcccgg ctttttgcga gaattgcatt
      301 ttgatgaagt ttacactttg gacattgcat ttttgcaatt atcttgtata atggaagtat
      361 gcggaggagg tgcgtgtcta tggctttacc cggaacaccc ggacagcgga tttccgattt
      421 atgcaacggg aaccacatca cacaaaagga acttgcggag aagataggcg tttccgcttc
      481 ccaattgagc cgcattgtca gcggcgaaac aagaacggta agcagtgata ttctcatagg
      541 tgtggcaaag gaatttaagg tatcgacaga ctacatactg ggcttgtcta ccgtgagcgt
      601 ccgtaaaagt tacgatattt ctgaattagg cttgtcagag ggggccgtga gggggcttgt
      661 gacgggtgct gttgatgtgc aaatcctcaa ccgtctgttg gaacacagga attttcccaa
      721 gctgatagat ttgatacgga tttattttca ggatacggcg gcaaagggca taacagcaag
      781 aaaccagctt atcgagatgg caacggcttc cctgtccgac ctgatgaaag aacacccgga
      841 acaccgggca gaagcgaagc aggatttaca gcttttgaac gcccaaaaga tgggggaaca
      901 tgaagcggag attgaaaaaa tcaaaaatgt gttcctggct atcctgcggg acattaagaa
      961 agacatagac aacggggaac agccgggaga agctgtgacc gccgctatgt tccaagccat
     1021 gcgggacgca ctggcggaac agaaacaaaa accgctttcc attgacgatg tagcggcgat
     1081 ggttgccgga cagatcggac agcttacgcc gatggatgaa gaaactgccg acctgttcaa
     1141 gcagttggca aaaaagatga tgaaaggaat agaataatag cctgttattc gagataataa
     1201 tatgccatta gtaaagcatg actaccctgt tttagagtac gataccgcat caaaagctgt
     1261 ttttcagccg ggaaatggga aaaaatgttt tcctgcaaaa gcagtgtttg cttttttagg
     1321 agacgaggtt gaaaattatg cacataccca tgatggaata cagatagatg aatttgaaag
     1381 tgcaacaaga cgatatccta tttatgaatg tctttataat caggagaaaa tatgtctatg
     1441 tccggctcct gtgggaagtg ctgctgccgt ccaagtttta gaatatttaa ttgcaggggg
     1501 tgtaacaaag attatttccg tcggctcctg cggcgtattg gaagacatcc cggaaaatag
     1561 atttttgata cctgtttctg cattgagaga tgagggaaca tcttaccatt atcttcctcc
     1621 ctcccgagaa gtagagattt caaaggctgg tataaatgcg attgaatctg ctttaagcca
     1681 aaagaatata ccatattggg aagttaaaac atggacaaca gacggttttt atcgagaaac
     1741 agtagaaatg gttcagtatc ggaaagaaga gggatgtcaa gtagtagaaa tggaatgttc
     1801 cgcattggcg gcgtgtgcaa aatttagaaa agttacatgg gctatgctgc ttttttcagc
     1861 cgatactctt gcagaccctc ataaatacca agaaagagaa tggggaaaaa caagtatatc
     1921 catagcctta gaattagcct tagacgctgt tttatcagtt gttgaggagt aaaaataaat
     1981 acatatagga gttacaatga atataaatga atttccacaa caagtaaatc aagttatttc
     2041 aatagcagaa accatattac aaggtcaaat attggggata tatttatatg gttcagcaac
     2101 aatgaatggg ctgcgtccag atagtgatat agatatactg ataattacta aacaagaatt
     2161 gagtaattca atcagagcag atctaacaaa gcaattattg aaaatttctg gctccgtagg
     2221 ctgtattgaa aaaagacctt tagaggtaac tattatcaat caatctgata ttgttccgtt
     2281 gcaatttccg ccaaaatgtc agtatatgta tggtgaatgg ctaaggggag agatggaagc
     2341 aggagaatat ccgcaagcct gcaatgaccc agatataatg attttattat ggcaagcaag
     2401 aaaaaatagc ataactttga agggggcgga aagcaaagag cttattcccg ctatcccatt
     2461 tcacgaaatt aaaaaagcaa ttcggttttc tttacctggt ttgatttcca gctttaaggg
     2521 tgatgaaaga aatgtgttat taaccttatc acgaatgtgg tttactttag taacagaaga
     2581 aatcacgaca aaagatgttg ccgcaaaatg ggtaatttta aaattgccgg agagattttc
     2641 ccccctgcta acaacggcaa aggaagctta tttgggaaat ttgtctgatg aatgggagac
     2701 agtagaaaag gaagcgatgg cacttgtaga atatatgaaa aaacaaattg aggaattact
     2761 tagaacagag tagcaaagtt agcggggcca atcaacggtc aagatgaacg gcgcataaat
     2821 gcgccgccgt tgacagtccc gcccgtcttt gctaaagggt aatcaaggcg ggaaagccct
     2881 aaaatggctt cacacctatt tcaataattg gaggagataa aaatgagatc agaaaaggaa
     2941 gtttatgata ttgttttgaa ttttgcaaaa acagacaaac gcattcgcat ggttactttg
     3001 gaaggatcta gaacaaatac aaatattccg cctgatgatt ttcaggattt tgatattact
     3061 ttggctctgt cacaacaaat ggttgatttt tgacgagaaa tagcgtataa taatagtaag
     3121 aaacagtacc accgaaggag gtaattggat atgcctacta tcaaagacgc attagatatt
     3181 atcggtaagt tgactgtcgc agagcaggaa agccttaaaa caatgctttt aagtcctgcc
     3241 tttgtaaagt ctttgaatat tgaagatttc gtagcaaagg aacgctttgc aaatggtcgt
     3301 gtatgccctc tttgtggctg tatccatgtg gttcgcaatg gtcatcgtaa agatggcaca
     3361 cagcgatatg tatgtaagga ttgtggcaag tccttcgtga ttgctacgaa ctccattgtg
     3421 tctggtacaa gaaaagactt gtccgtgtgg gagcagtaca ttgattgtat gatgaatggc
     3481 ttatccattc gtaagactgc tgttgcttgt gggattcaca gaaacaccgc attcctttgg
     3541 agacacaaga ttttggatgc acttcagaat atggcagacg atgttaccct tgacggcatt
     3601 attgaggctg acgaaacttt tttcgccatc tcgtacaagg gcaatcatag caagagtaag
     3661 acatttgcta tgccacgcaa ggctcataag cgtggtcatt ctacacatat cagaggcttg
     3721 tcccaagaaa aggtatgtgt tccttgtgcg gttaatagga atggcttgtc tatctccaag
     3781 attacgaata ctggtagagt ttctacaaga gatttacatc atatttatga tggtaggatt
     3841 aagaccaatt ccactcttgt tacggacaag atgaactcct atgtgagatt tacaaatgcc
     3901 aatggcattg accttgtgca gttaaagact ggcaaagcca agaaaggcat ttataatatc
     3961 caacatatca atagctacca tagccagcta aagaggttta tgcgtggctt taacggtgtt
     4021 tctaccaagt atctgaacaa ctatcttgtg tggaataacc ttgtaaatta cgccaaagaa
     4081 agcgacatgg agaaaaggaa catcttctta acttttgttt tggcaacatt gaaaactgct
     4141 aaatgcagag atttatcaaa cagaccagca gttcctctgg tcgcctaatt agaatttgtg
     4201 gagatgataa gatggtcaat ataacagatg taaaacagat tcttcaattt gcaatagatg
     4261 cggagattaa agtctttctt gatggtggat ggggtgtaga tgctcttctt ggatatcagt
     4321 caagagccca taatgatatt gacatttttg tagaaaagaa cgattatcag aactttatag
     4381 aaataatgaa agctaatggc ttttatgaga ttaagatgga atatacaaca ttgaaccata
     4441 ctgtatggga agatttgaaa aacagaatta ttgatttgca ttgttttgaa tatacggacg
     4501 aaggtgaaat tctttatgat ggggattgtt ttccggtaga aactttttcg ggtaaaggaa
     4561 gaattgagga aatagaggtt tcctgtattg aaccatatag tcaagtaatg ttccatctgg
     4621 gatacgagtt tgatgaaaat gatgcacatg atgtgaagtt attgtgtgag acacttcata
     4681 tcgaaattcc aaatgagtat agataactgc aaataacagt ttgtagggga gttctgatac
     4741 tcccctataa aaatggctat ttatcaactg tttgttgtga catagccatt actttttttg
     4801 ttacggatat ggacagcttc acaagtgatg ataaatggct agatatattt ggtgaaaggt
     4861 tgattctgca aaagccggaa gatatggaat tatttccagc tgtagaaaag ggattttcat
     4921 atttaatgct gtttactgat gatgttaaga tagatttaac tttgctgccg ctggaactga
     4981 tagacgagta ttttacatgg gataaactgg taaagttact gttggataaa gacaaccgta
     5041 tcgtaaagcc gccaatacca acggatatag actaccactt gcagaagcct actcaaagaa
     5101 tgtttgacga ttgctgtaat gaattttgga atactacaac atatgtagta aagggcttat
     5161 gccgcaaaga aattcttttt gctattgacc atatgaatga tatagtacga aaagaattgc
     5221 ttcgcatgat ttcctggctg attggtatca aacagggatt tcatttcagt ttgggaaaaa
     5281 actataaatt tatgaagcaa tatgtcccag aggaattgtg ggaacgactt atgtccactt
     5341 ataatatgga ttcctatccc catatgtggg aatcctttga acaatgtatg gcattgttcc
     5401 gggaggtttc gtcagaagtg gcatgccagt tggattacca gtatccacta tatgatgaaa
     5461 aaatcagtaa ttatgtgatt cggcaaaaga aaaaatatgg cattgaagat gataacaaat
     5521 aaaatttttt caatcgaaaa aatttatttt gattattcaa ttttgaaaaa ctgaatacct
     5581 caaaatcaga aagagagcgg ccaagcactt tgagggattg gccgccttgt ccacccatcc
     5641 agcgggacag cgggcggagg tcaaggccgg gtgtaaaccc gttcatttca gccttgacgg
     5701 ttgcccgttg tcctgctact tttccgggag tgtggccaca acttcgggac actttgtcca
     5761 caagttggag cgtaggacga gggacggggg ctttcatata cctgccgccg ttctctgaaa
     5821 acagcccgat tttttgctca ttcccattcg caaaaattca gcctgttttc ctgacggagc
     5881 aaacggggcg caagaagcac cgcaccccgt ttcctccgtc agccacgcca gcaggtataa
     5941 cacactacac tttgcaagca aagtcgtgtg ccaaaggggg cacccctttg gaaaccccca
     6001 caagaaaagg cggtacgcta cccctccacg gggcgcatac cgccgtttgt tgtcagcagc
     6061 ccgtttcacg gtctgttttc gccctttgta aagtttggcg tagcaaactt tgtaggtact
     6121 tcaaactgta ttgaaaaaga agattatgtt aattttaata ttgaaaaaga gacaaagcct
     6181 tatatttata aaagacctga agaaatggta ttattgcaaa ataccaacca aagtggtttt
     6241 ataaaagtaa aagtagaatc taagaatttc ttaggagcaa ttttagaata tacagtatca
     6301 aataatggaa aaaaatatca agtaactgaa cttaatagac tgaataatag caataaatta
     6361 aacgtagggg atatggcata tttaggtgtg ctacaaggta actaatatga ttaaaaaaat
     6421 aaaacgtagt aaatttacac ctaaaaatgt tatttcgatt attttataca gtatattatt
     6481 ttggattttg attggatata ttatcatacc aataggcaat acctttacac aagcatttca
     6541 aggtaaaggt ggatattctt ttgaagtttt taaagaatat ttttcaaata ctaataattt
     6601 aaaggtagta agcaatacta taattttggg atttggttct gtactcgtat gtggaattat
     6661 gggaatatca cttgccttat atatgacatt tgtttgtgat aaacacaaga aaatcataca
     6721 tattctttta ctaagtccaa tgatgattcc tggagtaatt atggtaattg catgtattca
     6781 gctttatgga gaaagtggga tagtcacaaa atctatagaa attttactat cctttatcaa
     6841 aaaaccttat gattttagtg gattaaaggg agttttattt gtggttgcct atactcagta
     6901 tgtgtatttt tatttaaatg tatatgttgc cttaaaatat gtggattatt caacagttga
     6961 agctgcaaaa ggaatgggag catcaaagat aagagtattt tttgatgtaa tatggcctgt
     7021 tattacacct gccattataa cctctactat tataactttt gcatcaggta ttagttcttt
     7081 ctcagcacca aatcttatag gtggtggttt taaagtttta agcactcaga ttgttaggtc
     7141 taaggctaat aaccacatgg atatagcttc agttcaagta attattttgt tactaatggg
     7201 gatttcattt atgattttat tacagtacta tggaaaaaaa tatggagtag tagcatcctt
     7261 aaagtctcaa ggttataaag ttcataatag aaaaaaagac ttatttacat ttgtatgtaa
     7321 ggttattatt gaaatacaaa ttgttatgat catgcttcct atagttacta ttgtgtattt
     7381 atcctttgta agcacacatt caattatgac aactatattt cctagagact ttacactgga
     7441 aaactatcag atgattttcc aaaaatcacg tgtgttacag cctatattaa acagcttgaa
     7501 aatgtcttta atggcagtag taataggatt gataatcact ataccagtat cgtatttagt
     7561 aattaagaag gatactacat ataatcgact agcaaaattt attataatgc taccttggag
     7621 tatgcctgca agcgccattg cagttaacct aattaataca tttaatcaaa aaagtatatt
     7681 tgcttttaat gaatccttaa taggaggttt ttatattgta cctatagcat atacaattta
     7741 tgccctacca ttattatttt catccaatga ggttgctatg aagtcaataa atttaggact
     7801 agaagaatca tcaaggagtt taggtgctgg aaggataaaa accttttata atgtaatagt
     7861 accaaatatg atgccaggaa taatttcagg agctatatta gtattcattc gtacaattgg
     7921 ggaatataca atgtcagcct tgctttatgg tgtttataat agacctattt caatttctat
     7981 tgtaactaat atgcaagaat ttaagatagg agtatctatg gcttatggtg tattagtaat
     8041 tggtatatgc tatatagcat taggaataat ttttaaatta gatagaaaaa gatttacata
     8101 agataataaa ggttaattta taaattggtg cttagaaaac caaatcactt tattagctag
     8161 agatgaattt ggagggtgtc attttggtgt tttgtgtaaa gtttatggaa gtaaaacatt
     8221 agataagcgt gagtatgatt catataaatc gtatatacta ttgaaatcca cgaaaaggta
     8281 ttggctaaat agctaatatc tttttaattt ttttgactct aatataacat taactattgc
     8341 atgagtatct ttaaatttat agttaaagta tcttaattgt ttattataaa aatatagtaa
     8401 ggttaaagcc tattaaatta aaacgcttaa gacgaaaaga tgtacatgag aggtataatt
     8461 aactatgata aagacttcta aaaattattt agtgaaaagg aactaagagt gtataataaa
     8521 agttcctttt cactaaggaa aacgattgtt attttcgaac cgtcattacc ctgatattat
     8581 ttaaatataa acaacaacaa aattaacaag aatcaaattc aacctaaaat ttaaaatatc
     8641 gggaggtata atatgttaat aaatatgaag gaaatgctaa aagtggcaca agaaaatcaa
     8701 tttgctgtgc cagcatttaa tataggaagt gggcaaatac ttaaagcagt agtacagagt
     8761 gctaacgaaa aaaatgcacc agtaatcctt gcaatacacc caaatgagct aagcttccta
     8821 ggggatagct ttgtagctag ttgtatagaa gaagcaaata agagcaaagt acctatggta
     8881 atacacttag atcatgggga aaataaagaa caaatattaa gagcaataag atgtggattt
     8941 acatcagtaa tgattgatgg ctcacattta ccatatgaag agaatgtagc tatatctagg
     9001 gaagtagtag aaatagcaaa aggattaaat gtatctgtag aaggagagct tggaacaata
     9061 ggaacaacag gaacatcaag tgaaggtggt actgatgaaa taatatatac agattcaaaa
     9121 ttagctaaag attttattga aaaaacagga gtagacacac tagctattgc aattggtaca
     9181 gcacatggta tatatccaaa aggttttaaa ccagagctta aactagattt attaaaagaa
     9241 ataagagaag tagtagatat acctttagtt ctccatggtg gttcatcaaa tccagatgaa
     9301 gaaatagcac aagcagttaa actaggagtt tgtaaaataa atatttcaag tgatgttaag
     9361 tcggcatatt ataagaagtg cagagaagta ttagaaaaaa attcaagctt atatgagcca
     9421 gacactatat atccaccatg tatagatgct gcaagagaag ttatagagtt taaaatgaat
     9481 ctattcaata ccatagataa attaaagtgc ttttataaaa acaagaatta attataaggt
     9541 aacaaataaa aaggagggga gaatttatga taggtcaaat actacgaagc gattgtattg
     9601 tactagataa acaattacaa acaaaaaaag atgtgattga ttatatggca aatcatttgt
     9661 accatgggaa ttatataaat gataaagaaa agtttatagt tgatattaat aaacgtgaaa
     9721 aagaatcatc aactaatatg ggtaatttaa tagctatacc tcatgctaag tcaaatgtag
     9781 taaatcaacc tgtaatgatg tatttaagaa ctgataagga aattacggat aatgatggtc
     9841 aaaaacttag gtcatttttt atgatagcag ttccagagtc aggctcagat gaacatctta
     9901 agattatatc taaactagct acatatctaa tggatgaaaa tcttcttaag cacctactaa
     9961 gtgcagaaac tccatatgaa atattaagta tatttaataa taaagctgta gaatcaggag
    10021 attcaagtga taatcaaaat aaaggtctta tagttggaat aacaggatgc ccaacaggga
    10081 tagctcacac ttttatggca aaaaaagcat tagaggaagc ggggcaagaa cttggatatg
    10141 aagttaagat agaaactcat ggagcgatag gtgtagaaaa taagttgact aaagaagata
    10201 taaaaagagc tgaatacgta ataatagctt gtgataaaga agttcaaatg agtagattta
    10261 taggaaagaa agtgttacaa aagaaagtag cagatgctaa gaatgtttca ttagctaaaa
    10321 atttaattat aaatgctgaa aatggaatgg ctaaagaaat taaaccaggt ggaagaactt
    10381 tagaagattc aaaagaaata ctccaagggt cagagaaaaa aggtgtttat aagcacttaa
    10441 tgagtggtgt atccgaaatg attccatttg tagtaatagg tggaattggt atagccatag
    10501 catttatgtt tgggatattt gcatcagacc caactcatga aacatacaac cctatagctg
    10561 gattctttgg acaacttgga ggagattcag catttaagtt atttatacct atacttgctg
    10621 gttttatagc taaatcaata gcaggaagac aaggttttgc tcctgctatg atagctggtt
    10681 ttatggcagt tattggaggt tcagggttta taggtggtat ggtggcaggt ttttcaacag
    10741 gatatatagc cttgggagta atgaagataa cagaaaattt accagatgta ttaaaaggag
    10801 taaatgctgt attgatatgt ccactgttga ttgcatttac aagtggagct ataatgttct
    10861 ttgtagttaa tacaccagca tcatggttaa atgaagcttt acaatcttgg ttacaaagca
    10921 tgtctggaac taataaagta ttattaggtg caatattagc aggaatgatg gcatcagata
    10981 tgggagggcc tattaacaaa acggcttcag cttttggatt ggctatgttt tcaagtaata
    11041 tatttgaacc atcagcagct ttaatggtag gaggaatggt acctccatta gcgatatcat
    11101 tagctatgtt gatattcaaa aataagttta ctaaagaaga aagaaagtca tctctaccaa
    11161 ctgctataat gggagcatct ttcataacag aaggagcaat accgtttgca gctgcagacc
    11221 cattaagaat gattccagca aatataattg gttcttgtat aggtggggca atatgtatga
    11281 gtttagatat aactttaatg gcaccacatg ggggaatatt tgtaatacca tttgcatgta
    11341 gttcaccagt tgcatatata gcttgtatat tgattggaac agtaataaca gcattgatta
    11401 taggggtaac aaagcctact ataaggagtg aaaatagtga agttgaagta cttggggctt
    11461 aaattataaa tgatagtaaa aataagtaat agaataacca caagtacata gaataaaaat
    11521 aaggatattt agaattagtt aactacttct aaatatcctt attttttatt ttgaaattat
    11581 atttctatta tatcaattta ataaggtgta tcataaattc ttttatgata cagaagtatc
    11641 ttagtaattt tacatagtta gtaaatatgt taaaatagta cttaatatga acatagaaat
    11701 atataaacat aggtagggag ggataagtat gcttgtgtcg aggcaaattg aatttcttaa
    11761 attgatatta aacgaaaata aatatagacc tataaaatac tttaaagata aattaaatgt
    11821 atccgataaa actttacaaa aagatttgaa gattattgag aaatacttag aaacttttaa
    11881 tataaaaatt gatataaaaa gaggatatgg aatattaata gaatctttgg caaagaagaa
    11941 tatagactta attaatagtt taaatataca atcgaaggaa aataaatctt tatcagtaga
    12001 acagagaaga atggagattt taaagtattt attactaaat tcaaataata taacttcaat
    12061 aaatcagtta gcagataaat attatgtgag taaaacttct atagtaaatg attttaaata
    12121 tatagaggca tggataaaag aatacaattt gaaacttaat aaaactttag agggaactaa
    12181 gattataggt aaagaagtgg atataaggaa atcgattgcc aaaatgatgg atgatttatt
    12241 agatgaaaat tatgaacagc atgatatatc taagttaaca agattagatt ctgctacatt
    12301 tagtgcgttg ataaatttat ttgatattga ttctattata tttgtagaaa ctataattac
    12361 agagttagaa tacaatttag gatacactat aagtcagccc tactatataa atttaattac
    12421 ccatatactt atatgtttaa agagaatcga agaaggtaat caaatagagt ctcaggaaga
    12481 aagagaagtt tctgtagata atttggatga attagtatat caaaatgtca ctgcacttat
    12541 aggcaaaata gaaaatagat acggagtaaa aataacgaaa gatgaaatta tgtacatata
    12601 tattttttta gtgtcatctg gatttagtag cgaaagtaat aatagttaca atgatgaatc
    12661 atatagatta agtgaaagtg aaaagttttc atctataatg atagagaata tgtcgcaatt
    12721 tttaaatata aatctcaaaa atgatgactt actacaaaaa agtctagcat ctcatgtaag
    12781 acctatgtta aacagattaa gatatgatat ccaaataaaa aatccattat taggagagat
    12841 acaagagcga ttttcagatg tgttgggatt atgtatgatg actataaata ttatgacaga
    12901 gtatgataat ctgaagaaca ttagtataga tgaagtttcg tatcttgcca catattttca
    12961 agcagcaata gagagaaata tgagtagtaa aagagtaata gtagtttgtc atacaggtta
    13021 tggaacatct cagctacttg cagccagatt aaaaagagaa tttcctgaat ggactatagt
    13081 tgatatagtt cctatgcatc agttgagcaa tcgaaattta gatgatgtag actttgtaat
    13141 atctactgta aacctagact tgaaagataa attacatata gttgtatcag tactattaat
    13201 ggaaagtgat attagtaata taaaaaatgc cttactttct aaacctaaga aaagtatgaa
    13261 cttagataca aacttattag gaatgtattt agaagataat atatatttta attttgatgt
    13321 aatgcagatg gaaagtttaa taggcgtgga tttagggagt aaatataaat ctatttcatt
    13381 aggaaaggat ttaaatatat atatacataa tcaaagtaaa ctaaataaag ggataatgaa
    13441 tgtcaataat attaatagaa caattgatat ttatttagaa actagtaatc aaagtttttt
    13501 aaagaatatt ttaatggaaa tatcaaattt atataggcaa aagagttata taaactatat
    13561 aatagattgc aagagcaaag aggatattaa aatattattt aaaaataatc tactggagaa
    13621 aacaaatgga aattagagaa atattaagcg aagaaagtat tattttagat ttgaaatcaa
    13681 ctacaaaaga aggtatcata caagagttgg tagataaatt atacgataca ggaagtatag
    13741 atttaaaaag taagtttata aaggcactaa aacgtagaga aaaaataggc tctactagta
    13801 taggttatca aatggccatg ccacatggaa aaacaaaata tgtaaagaag gcatctgtgg
    13861 taataggtaa atctaaaaaa ggtatagatt ggccaagtat agatggctta cctgtaaagg
    13921 taataattat gtttgctatg ccacaatctg gagacaatga agatatgaca ttaatatcta
    13981 aaatagcgta tattttagga ggtaaagata taagtgaaag acttttaaat gcaaatacaa
    14041 aaaaagaaat attagatata ttttatgaag tgtaggtatt gtataaatta taattttgag
    14101 gtttttaaaa taaagtatgt attattttaa atagtatata ttaattttta gacactagaa
    14161 aggagaggat atatatggca atatatttag aaatgcctaa attaatacat gaatttcctt
    14221 ttcgtagtct atcaaatgaa ggagaagtat taacaacacc acactggcat aaagaaatag
    14281 aaatattact tataacagaa ggtgtagtaa atctatttat atggaaataa aaagttgaca
    14341 aaatatgtat gatgttttat catagtaatt ggaattaggt agtaattgtt taagtacaag
    14401 ctaagcttat tcattaataa tagcagtatc ctaggaagga gtatgcccat tattatggat
    14461 aagttttttt tatgcttaaa aggaggataa tcatgataat taataagata ttaaacaata
    14521 atgttgtaat cacattagat gataatgatg aagaaattat cgtcatgggt aaaggaattg
    14581 gttatcaaaa atcaaaaggc aatctaatag ataaaactaa agtaaacaaa gtatttagaa
    14641 tatcaaataa agaagtatca aacaaactac aagaattact caataatatt cctatagagc
    14701 acatgaaatt atcaagtgaa attatagagt atgcacaaat aaagttaaac aagaagctaa
    14761 atgaaagcat ttacatatcc ttaagtgacc atacatattc tgcaattcaa agaatgaaag
    14821 aaggaataaa tgtaaaaaat gcaatccttt gggaaattaa aagattttat aaagaagagt
    14881 ttgaaattgg aatgaaggca ctagatatta ttgaaaataa aacaggcgta aaattacctg
    14941 aagatgaggc tggatttata gcttttcata tagtgaatgc tcagctaagt gaggggcata
    15001 cttttgcatc tgatattaca aagttaatac aagaagtact tagtatagtt aggtatcatt
    15061 ttaggataga atttcatgaa gaatcagtgt tttattatag atttataatg catttgaaat
    15121 tttttgcaca gagattactt ttaaataatg cacatgaagg tgggacagat aaagaattat
    15181 taagtattat taaatctaaa tataataaag agtttgaatg tgtagttaag attaaggatt
    15241 ttattaaaaa acaatataac tacatatt
//
LOCUS       DBGJFK010000168        12839 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.099, whole genome shotgun sequence.
ACCESSION   DBGJFK010000168 DBGJFK010000000
VERSION     DBGJFK010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.099"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            278..1210
                     /gene="blaCDD"
                     /locus_tag="ACOIAP_003636"
     CDS             278..1210
                     /gene="blaCDD"
                     /locus_tag="ACOIAP_003636"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HGZ2640467.1"
                     /translation="MKRKKNFIWTTILLVGIVMVMYYAGKKHNDINQKTDKNYIKSDL
                     NKSEINNDNNKKERVNIVNYSDCFEGISGGAIFYNSRNQEYNIYNKDLIETRASPCST
                     FKIISTLIGLEKGVITSKKSVIGYDGTNYPNKNWNKNLSLEEAFKESCVWYYKKLINK
                     VDAKSVQSILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMVKIF
                     EGDTNFKKEHINILKDIMKIDVSDKNINVYGKTGTGFNGKNKRVDAWFVGMLESKDDT
                     YYFAIKSDDSNKEIAGPKVKEIAINIIKKYYSVM"
     gene            1559..2242
                     /locus_tag="ACOIAP_003637"
     CDS             1559..2242
                     /locus_tag="ACOIAP_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640468.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHMLGGVDRPTSGKIYVEDTEISSLNEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     TILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2239..4899
                     /locus_tag="ACOIAP_003638"
     CDS             2239..4899
                     /locus_tag="ACOIAP_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640469.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDDTYGKDLSLIENFSSVDDVMVKGQWYVGKINNDKRDYI
                     VYRNATSEYWNHMPEKDSIIEGRRPSNTNEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPVAPKSKGESFKKISKTTLTIVGKVDVATSSVVPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SNISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNKLIVYINSVNYHTDAPEVVFTYGIPAFLPAVLL
                     TIVTVWISTLIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTGFLHIIANQEGAEAVYGSDNYKDQRDIEVYLENSEPVE
                     SDFIEKLDNTEGVKNSLYYQKMSATTWLTEKDASKELSKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDESFAEYCRQISVDPKLFYDTKNPTSIVYNKEEDVNRSTRRNKVY
                     IDYLNLSIGDNIKLNEKIYDEDKGDYTYNMKVGAITSTLPKIIDTSSRYTLMQIVPIS
                     MVQEISKNYAEVGRSRSNRLIGLFKVDNREDIPRVRGKLESICNKDYGSGDYSIEDVV
                     ENEKQNGSGRKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPD
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYTFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYNQLKNENIVESIKSETI"
     gene            complement(5076..6257)
                     /locus_tag="ACOIAP_003639"
     CDS             complement(5076..6257)
                     /locus_tag="ACOIAP_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2640470.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKVL
                     DASYEYNPKSTESILKSLKNSSDEDFKTGNEILSKHGYSKGTFWSKNFFYFLVVSFGI
                     ISTMAIVVYIIKYRTNKQKLSRINMLTRYLEEVNLGKESVLLRYEDEFSYLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TKQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     KGSPSIEFEIDINWTLEALLNILKNCSEHIEAGGHIIAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6257..6919)
                     /locus_tag="ACOIAP_003640"
     CDS             complement(6257..6919)
                     /locus_tag="ACOIAP_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640471.1"
                     /translation="MAKILLLEDDDTITFGIKTSLENKNHIVCCYNTIAEAKKNFDKT
                     TDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRAHSNTNNTITCGNISLNKVEVKAYLDSVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7035..7673)
                     /locus_tag="ACOIAP_003641"
     CDS             complement(7035..7673)
                     /locus_tag="ACOIAP_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGZ2640472.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFSLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSKKSDTEMLFKEKFFSFNKFMFDEIQEMFEIGKNDGSIRYDI
                     EISTLMYSSIFTLTGFFNLLSVTRKSYLNNFNIDEEKFIETTLAILIDSIKA"
     gene            7853..8458
                     /locus_tag="ACOIAP_003642"
     CDS             7853..8458
                     /locus_tag="ACOIAP_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGZ2640473.1"
                     /translation="MKIKENVLRLDSTRGSNCFIVFDKEITLIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHMSNIKLLKEKTGAKVWAHTEDIPFIIGEKDRPGFKK
                     FIGKTISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVSYPNPWNWDSKKMMKSIRELDNLEYEWICMSHGTPCIK"
     gene            8559..9281
                     /locus_tag="ACOIAP_003643"
     CDS             8559..9281
                     /locus_tag="ACOIAP_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGZ2640474.1"
                     /translation="MIRTLILYYLNIKPTHGYEIQKFLQVSGADRWTKIQSGSIYYAL
                     AKLEKDGGVRVLKEEKTGARIRKIYEITQSGKLELREEIQKELQMPIVPTGSNKFLLH
                     NILDVLPKDTLQKNLEKHIKYLIEQKKYWENWKEIKKIDKKSLATEKIAFDMTIDNLN
                     YQILWHEEILNDIDKYISVGCETQNIIKSIDFSNIEEDFLFTSDTTNELLEVQRLRDE
                     IINNPDKAIENIDKIILKLQNK"
     gene            9383..10141
                     /locus_tag="ACOIAP_003644"
     CDS             9383..10141
                     /locus_tag="ACOIAP_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640475.1"
                     /translation="MSNILLEIKNLSKKYNNKEVVSIESFKLLEGDILGFIGANGAGK
                     STSINMLTTIVSPDSGSIYYKGKDIKNQQNIFKSSLGVVPQELAIYEDLSAYDNVKFF
                     CSLYGFKGNELKERTKDALEFVGLWESHKEFPSKFSGGMKRRLNIACAIAHSPKILIM
                     DEPTVGIDPQSRNKILEAIKCINTNGTTVIYTSHYMEEIETLCNRIALIDKGIIIEDL
                     DKSLYKNKYLEFGCKTLEDIFLYLTGTDLRDLEE"
     gene            10146..10886
                     /locus_tag="ACOIAP_003645"
     CDS             10146..10886
                     /locus_tag="ACOIAP_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640476.1"
                     /translation="MRCFLPLFKLGIKRRSKDFFILFYNIVFPVIIIMLLGYLTSKSY
                     GEEFTSYNYYTIVTIPFCVLMGIISVSYAGQDEKISNTSYRYMISPISIVDLVISKLF
                     SCTAVLSICNLVTLVVLKCIFRMSFGGKFLAVLFFLMCESIVVVSMGLFLGLVCKNLD
                     MLRNIINIPIVIFGFLGGVFFPVSSLNPVISLIINISPLTWINRGIVACIYDNNLQLL
                     FNISCIFVVVSIFMTILTIKFFKKGVFI"
     gene            10886..11938
                     /locus_tag="ACOIAP_003646"
     CDS             10886..11938
                     /locus_tag="ACOIAP_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640477.1"
                     /translation="MNVINVFNINLKRNINKRIVFLVTLLFPIIIVILGVLANYISKP
                     FFNIGILDEYKNERVLKESEKRTYENTIMALENTQGINTKIADFKTIKTDIITGKYSA
                     VIYFNKNGFKLYSIKNKNTNDTLKYLIETYKKDPVPVDISKLQENTLGVLQRIIAFIV
                     LFLMITSTVTASMIIKDKNSGTFTRVLYSPQNVRGYVLGNMLYNFTITYFQYIVSISI
                     IKLFNIDIGMDYIDLILMGIWVVALATSFGTFVSSLFNREMHANLFSTCISLVLSLIG
                     GSFISVEKMPEMLQKISIISPVRWFISFVTYIEERDGSFFNMNYICILTSIIIVLALL
                     AMKFTQRSKYSSNSNY"
     gene            12340..>12839
                     /locus_tag="ACOIAP_003647"
     CDS             12340..>12839
                     /locus_tag="ACOIAP_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640478.1"
                     /translation="MNNLFYDKLNFDDKLIIKNNGVIRNNDLYFLKYKNDTAGILIYN
                     IINDKFSFKQNKNYKGMNPFPITNIFKNLDSDKWDEFIRIWIEERVIQECRPEVPFIL
                     KEFKLGYYDVWDICRSNLAMSVEDFFWITKDNTLRYEDFNIRYCTLNNITPIYKPPFP
                     IVIYPN"
BASE COUNT         4851 a         1492 c         2016 g         4480 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaaagt agaatcaaat actatatcac
       61 aaattaaaag gaggacaaaa tgctattaat agttacctaa ttattttcgt aataggttta
      121 atcgacatag ttgtgctagg tgaagaaaat ataagatata tagttattcc tttagtctta
      181 ttttttataa gtagcaccta gattgaagta tattacaaat aatgtctact attttaaaag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggacaact atcttgttgg ttggtatagt tatggtaatg tattatgcag gtaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttacataaaa tctgatttaa ataaatctga
      421 aattaataat gataacaata aaaaagaaag agttaatata gttaactata gtgattgttt
      481 tgaaggtatt agtggaggag ctatttttta taatagcaga aatcaagaat ataatatata
      541 taacaaagat ttaattgaaa caagagcttc accttgttct acttttaaaa taatttcaac
      601 attaattggt ttagaaaaag gggtaataac gtcaaaaaaa tcagttattg ggtatgatgg
      661 tacaaattat ccaaataaaa attggaataa aaatcttagt ttagaagagg catttaagga
      721 gtcttgtgtt tggtactaca aaaaattgat aaataaggtt gatgctaaat ctgtccaaag
      781 tattttagat gatttaaagt atgggaactg tgatattagt gaatgggaag gagatttaaa
      841 aaatggaaag gggcatttaa atggattttg gttagaatct tcattacaaa tatctccaaa
      901 agaacaagtg caaacaatgg tgaaaatatt tgagggagat acaaacttta aaaaagaaca
      961 tattaatatt ttaaaagata ttatgaaaat agatgtaagt gataaaaata taaatgtata
     1021 tggaaaaact ggaacaggat ttaatggaaa aaataaacgt gtagatgcat ggtttgttgg
     1081 tatgctagag agtaaagatg acacttatta ttttgctatt aaatcagatg attccaataa
     1141 agaaattgca ggaccaaagg taaaggaaat tgcaattaat ataattaaga aatattatag
     1201 tgtaatgtaa taaacttaat tttatttgta aatattggtt acctatagtc tgtaaatatt
     1261 tattaaataa ttttactaaa ttgagtttac atagagcaaa actcctctag tatataaaat
     1321 acttgctatt gattattaaa ttgaatactt atagatatta aagttaatat cttttaaagg
     1381 ctatgcaata tattaaaagt ataaataaaa tatattgcat agtttttgtt ttgtattata
     1441 attttaaata atgttcaaaa actaaacaat atttttaata gtaatcgata tttgtattca
     1501 tgtcactata atgtcatttt aggttgctaa aatttaacca taaaggagat gagtgtatat
     1561 ggaaatatta aaatgtgaaa atctcacaaa aatatatggt tcaaatcaaa ccagagtgac
     1621 agctcttaat aatgtaaatt tatcagttca aaaaggtgat tttgtatcca ttgtaggagc
     1681 atctggttct ggcaaatcta cattgctaca tatgcttggg ggagtagata gacctacatc
     1741 tggaaagatt tatgttgaag atacagaaat atcaagctta aatgaagaag ctcttgcagt
     1801 ttttagacgt agaaaagtag gtcttattta tcaattttat aatcttatac ctactcttga
     1861 tgttagaaaa aatatattat tacccatgtt acttgataaa agaaaggtgg atgaagatag
     1921 attctctgag attgtatcta tattaggatt atctgataga ttgaatcatc ttccaagtca
     1981 actttcaggt gggcaacaac aaagggtatc tatagctaga agtttaatct atagaccaac
     2041 tattttatta gcagatgagc caactggtaa tctcgataga aaaaattcag aagaaattgt
     2101 agatttgtta aacttatcaa ataaacgatt taatcagaca atacttctta ttactcatga
     2161 tgagaaaata gcactagagg caaatcgtat tgtaactatg gaagatggag tgattgtctc
     2221 tgaaaaggtg gtgaagaaat gaatattctt caagaatata ccttagactt tgtacgacgc
     2281 aataaacgta gtagtatagc tataatgtta gccatattac ttaccacaac catgatgtct
     2341 tccttgtgtg gattgttgta taccatgtgg acagatttta taagactttc aattgagaaa
     2401 gagggtaact ggcatggtga attgtttgac gatacttatg gaaaagactt atcgttaatt
     2461 gaaaattttt cttcagttga tgatgtaatg gtaaaaggac aatggtatgt aggcaaaatt
     2521 aataatgaca aaagagatta tatagtttat agaaatgcta catcagagta ttggaatcat
     2581 atgccagaaa aagattctat aatagagggg cgtcgaccaa gtaatactaa tgaaattgca
     2641 ctatcaaaac aatattttga gaataatcca agtgtaaaaa ttggtgataa aattactctc
     2701 ccaataggag atagaatcct aaatggaaag cctcttgaac ctgtagcccc aaaatcgaaa
     2761 ggggaaagtt ttaaaaaaat ttcaaagact acattgacaa tagtaggaaa ggtagatgtt
     2821 gctacttcat cagttgtacc tgcatataca gctcttggat atcttgataa aacaagtata
     2881 aaacctaatg acagtataac tgtgtacttg cgatttaaaa atataagaga cacatataag
     2941 gaacttccaa aacttgctaa atcattggga tggaagacta atgaatatgg aaaatacaat
     3001 cttaaataca atagtaatta tcttttaaaa atgttagtct tttctccaga acagaaagca
     3061 tctatgagca atatatcaaa attttcaact cctattatgt atcttacaat agcaattttt
     3121 acagtagccg tgtttgtaat ggtaatttac aacgcatttt cactatctgc aaatgctaga
     3181 cttacacaat taggaatatt atctagtgtt ggagcatcac caaaacagat taaaaggtct
     3241 gtagtgtttg aaggtttttt attgactatt ataccattac caataggttt atttttaggg
     3301 tggttattgt gtaataagct tatagtctat attaattcag ttaattatca tactgatgct
     3361 ccagaagtag tattcactta tggtattcct gcttttctgc cagcagtttt acttacaata
     3421 gtaacagtct ggatttctac actcatacca gcacgaaaag tatcaaaaat atctcctata
     3481 gaagcaatac gacaaggaga tagtgttaaa attaaaaagt cacataaata ttcattagga
     3541 aagatatttg gaatagaagg agaacttgca tcaaatgcac tacgtgctcg taaaaaatct
     3601 tatcgtactg caacaatatc tttaacatta tcttttttat tactgacagg ttttttgcat
     3661 ataattgcaa atcaagaagg agcagaagct gtttatggaa gtgataatta taaagaccaa
     3721 agagatatag aagtttattt ggaaaatagt gaacctgtag agtctgattt cattgaaaaa
     3781 ttagataata cagaaggtgt aaagaactca ctatattatc aaaagatgtc tgctaccact
     3841 tggctgactg aaaaagatgc ttcaaaagaa ctttcgaaaa atggaggatt taaaagtata
     3901 gtttcatcta aaaagtactc tcctatagag cgtgatggca agtttcgtat aatttcaaat
     3961 ataattgggc ttgatgatga gagtttcgca gaatattgca gacaaatctc tgtagaccca
     4021 aaattatttt atgatacaaa aaatccaact tcaattgtat ataataagga ggaagatgtt
     4081 aatcgtagca cacgtagaaa taaagtatat atagattatt taaatctttc aataggagat
     4141 aacattaaat taaatgaaaa aatatatgat gaagataaag gggattatac ttacaacatg
     4201 aaagtgggag ctattacaag cacacttcct aaaataatag atactagttc aagatataca
     4261 ttaatgcaaa tagtaccaat atctatggtg caagaaatat ctaaaaatta tgctgaagta
     4321 ggtaggtcac gttcaaatag actgatagga ttgtttaaag tagataatcg tgaggatatt
     4381 cctagagtaa gaggaaaatt agagtctatt tgtaataaag attatggttc aggagactat
     4441 agtattgagg atgttgtaga aaatgaaaaa caaaatggta gtggaagaaa gactatgaat
     4501 ttgatagtag gttttattac aggtttattg gctatgattg gattatcaaa tgtacttgct
     4561 acagtgtcag gaaatattag aagtagacga caagagtttg ctatgttgcg ttctgttgga
     4621 ttatctccag atggcataaa aaagatgctt gttttggaag gtttattctt aggaattaca
     4681 ccattactac ttagtattcc tgtgcaaata ggaatagtat atacttttct acgtataaat
     4741 gaaatatatt ttatagagta tttaccattt gcacctatat ctacaataat aggttttact
     4801 atattgatac tttttattgt aatagcatca tatatgacag gatacaatca gttgaagaat
     4861 gaaaatatag tagaatctat aaaaagtgaa acaatataaa taaaagttat ctgaacttat
     4921 ttatggtttc aattcaagaa tacttacgag tatagagata gttaaattgt ttatttaata
     4981 aaatcttaga tataaatagc ggattactaa aataataaat aacataggat atagatatga
     5041 ctggattatg ggtattttac ctataatcca gtattttatg tgtaaaactt aattatgaat
     5101 cttgcaccac cattatggca attttctgca tgtagagtac cattttgacg ttctataata
     5161 gactttgata gagcaagccc tataccaata ctgtccttac tagcgttttt accacgataa
     5221 aatctattaa aaatatatgg gagctcttcc tgagcaaacc ccttaccatt atcttctatg
     5281 ataatctcaa catatagagg gttttgacta taataagcaa tgatatgtcc accagcttct
     5341 atatgctcac tacaattttt aagaatattt aaaagagctt ctaaagtcca attaatatca
     5401 atttcaaatt ctattgaagg agaacctttg atagtaaatg tctgatgttt ttctcttaaa
     5461 gaaccttcta taggctcaat tgcataagta agaagagaat gtacatctat aagtttgctt
     5521 tcaaatatta aagtactcgc atccaatttt gataaggtaa gtaaagatga aactagtctc
     5581 tcaagtcttg atatttgctt tgtaagcctg ttaatataat ctatttcttc atctggacaa
     5641 ttttctgaaa gtaattgtgc cataagtgac atagaagtaa ttggagtctt aagctgatga
     5701 gcaatatctg caaggttatc tgaaagagtt tgtctttctt ttagagcaaa ttcttttgaa
     5761 caacgaagtt ccccaactgt tttatatatc tcatcttcaa gataagaaaa ttcatcttca
     5821 tatcttaaaa gtacagactc ttttcctaaa tttacttctt ctaagtatcg agtaagcatg
     5881 tttattctac tcaatttttg cttatttgtt ctatacttga ttatatatac aactatagcc
     5941 attgttgaaa ttataccaaa cgataccact agaaaataaa aaaagttttt actccaaaat
     6001 gtacctttag aatatccatg ttttgataaa atttcatttc ctgttttaaa atcctcatca
     6061 ctagaatttt tcagtgattt tagtatactt tctgtagatt taggattgta ctcatatgat
     6121 gcatcaagaa ccttagacag cacattgtat tcattaaaag aagtgatagt tgttagaatt
     6181 acactcaata aaaaagttac aattaagcag aatattataa aaacaactgt actgttgata
     6241 tttcttggag ttttcactag ctgtcctcca ttctatatcc tatacctctt aatgttttta
     6301 tacaaggtgg attttttaat ttttctctaa gacgctttat tgtaacagta agagtgttgt
     6361 catttacgaa attaccatct acatcccaga gcatttctag taattttgta cgagtcatag
     6421 ctctattttt attttccata agacttagaa gaagcttata ttctcctgct gtcagaggta
     6481 cttcaacact atctaaatat gccttgactt caactttatt caaacttata tttccacaag
     6541 taatagtatt attagtatta gaatgagctc ttctaagaac tgcattaatt ctagattgaa
     6601 gtactgaaag caaaaatggt ttaaccacat agtcatctgc acccatatct aatccacgta
     6661 taatgtcttt ttcatcatca cggactgtta aaaatatcac tggagtatct tctatacttt
     6721 taacgtattg gcaaaattcg tatccaatac catcaggtag atttaagtca agcagaatta
     6781 aatcagtagt tttatcaaaa ttttttttag cttcagcaat cgtattataa caacatacaa
     6841 tgtgattttt attttccagg gaagtcttta tcccaaacgt aattgtatca tcatcttcta
     6901 agagaagtat tttagccatt tacttttagt cctttcatta atttaaatta ttagttttat
     6961 gcttaatatt ttttatatta tatatagtaa agattaccat ttaagtatat aaattttaat
     7021 ttatatactt aggtctatgc tttaatcgag tctattaaaa tggcaagggt tgtttcaata
     7081 aatttttcct catctatatt aaaattgttc aggtatgatt ttcttgttac agacaataaa
     7141 ttaaaaaatc ctgtaagtgt aaatattgat gaatacataa gagtagatat ttcaatatca
     7201 tacctaatac ttccatcatt ttttccaatt tcaaacattt cttgtatttc atcaaacata
     7261 aatttattaa aagaaaaaaa cttttcttta aacagcatct cagtatccga ttttttagag
     7321 tttacaatac caatcattcc cataaggcat aatagagaag gttctacaga gtaaaattta
     7381 tgaaaagcaa agtatgaaag ttttattttt tcaaaccctg ttttaccttt tgcactttct
     7441 attttaacat tatcccaaag tcttttatat ccccttaaga caacagcaaa gaataaatct
     7501 tctttacatg aaaagtactt gtatatggtg cgtttagtat attcgacttc ctttgccaac
     7561 tcattcatag ttgtattatc aaatccatta agagaaaata atttttctgc tttatcaata
     7621 atttcatttt ctctttgtat tttttcttta tctctttttg ataattctga catataaatt
     7681 attcctttct attgataata aagtatactg gtggtatact tgtgtaaata taatatattt
     7741 gtatactatt agtatacttt aatgaaaata aaattaatat caagtattat agctatttat
     7801 aacttcatta attaattata taggcaaaat accaaatagg gggaatttat ttatgaaaat
     7861 aaaagaaaat gtattaaggt tagatagtac tcgtggctca aattgtttta ttgtgtttga
     7921 taaagagatt actcttatag acacaggtct tccttttatg gggaaaaata taattaaaga
     7981 attaaaaaca cttggtatca aacttacaga tattaagcat attttattaa ctcatcatga
     8041 tgttgaccat atgtctaata ttaaattatt aaaagagaaa acaggagcaa aggtatgggc
     8101 tcatacagaa gatatacctt ttattatagg agagaaagat agacctgggt ttaagaagtt
     8161 tattggaaag acaatttcaa gaaggctcat taaggatgtt gaaccttatg gagagaatat
     8221 gcagattggg aatataaaaa ttatccatac tcctggtcat actccagggc atgtctgcat
     8281 gatttttgaa gatgtattat ttgcaggtga tttagtcaaa aacaagaatg gaaatatagt
     8341 ttcttaccct aatccctgga attgggattc taaaaagatg atgaaatcta taagagaatt
     8401 ggataattta gaatatgaat ggatatgtat gtctcatgga actccttgta ttaaataata
     8461 aaaataataa gttgtaatat atcctatgtt atctattgac tatatccaag attggtgata
     8521 atataatatc caagatagag tataggtggt ggatttttat gatacgcact ttaattttat
     8581 attatctaaa tattaagcca acacatgggt atgagattca aaagttttta caagtatctg
     8641 gtgcagatag atggactaaa atacaatctg ggtcaatata ttatgcattg gcaaaattag
     8701 aaaaagatgg aggcgttaga gttttaaaag aagaaaaaac aggagctagg attcgtaaaa
     8761 tctatgagat tactcaaagt ggtaaattag aattaaggga agaaatacaa aaagagcttc
     8821 agatgccaat agttccaacc ggttcaaata aattcctatt acataatatt ttggatgtat
     8881 tacctaagga tactttgcaa aaaaatcttg aaaaacatat aaaatatctt atagagcaga
     8941 agaagtattg ggaaaattgg aaagagatta aaaaaattga taaaaagagt cttgcaacag
     9001 aaaaaattgc atttgatatg actatagata atctgaatta tcaaatttta tggcatgaag
     9061 aaatattaaa tgatattgat aagtatatat ccgttggttg cgagacacag aatataatta
     9121 aatctataga tttttcaaat atagaagaag attttttatt tacatctgat acgacaaatg
     9181 agttattaga agttcagaga cttagagatg aaataattaa taacccagat aaagctatag
     9241 aaaacataga taagataata ctaaaattac aaaataagta ataaatttta ttacaataac
     9301 acgggtaaaa tactcgtgtt ttaaaaaaat tatatataca atattggata tataatgttg
     9361 gttaaatatt ggggggttat aaatgagtaa tatattgtta gagattaaaa atttatctaa
     9421 gaagtataac aataaggaag ttgtgtcaat agaaagtttt aagttattgg aaggcgatat
     9481 tttaggtttc attggagcaa atggagcagg gaaaagtaca tctatcaata tgcttactac
     9541 gattgtgtct ccagatagtg gaagcatata ctataaagga aaagatatta agaatcaaca
     9601 aaatattttt aaaagttcac ttggagttgt accacaagaa ttagcaatat atgaagattt
     9661 aagtgcatat gataatgtta aatttttttg ctcattatat ggatttaaag ggaatgaact
     9721 taaagagaga actaaagatg ctttggaatt tgttggtctt tgggaaagcc ataaggagtt
     9781 tccatcaaaa ttttctggtg gaatgaaacg tagactaaac atagcttgtg caattgcaca
     9841 tagtccaaag attctcatca tggatgagcc aacagtaggt atcgaccctc aatcaagaaa
     9901 taaaattttg gaggcaatca aatgcattaa tactaatggt acgacagtta tatatactag
     9961 ccattatatg gaagaaattg aaaccttatg taatagaatt gctttaatag ataaaggaat
    10021 aattatagaa gatttagaca agagtttata taaaaataaa tatttagaat ttggttgtaa
    10081 gacattagaa gatatttttt tatatcttac aggtacagat ttgagagact tggaggaata
    10141 aatagatgag atgtttttta ccattgttta aattaggaat aaaacgaaga agtaaagatt
    10201 tttttattct gttttacaat attgtttttc cagtaataat cataatgtta ttaggatatt
    10261 tgacatcaaa gtcctatggt gaggaattta catcatataa ttattatact attgttacaa
    10321 taccattttg tgttcttatg ggaattatta gtgtttcata tgcgggacaa gatgaaaaaa
    10381 tttctaacac atcatatcgt tatatgattt ctcctatttc aatagtagat ttagttattt
    10441 caaaactttt ttcttgtaca gcagtacttt cgatatgcaa tttggtaact ttagtggtgt
    10501 taaaatgtat ttttcgtatg agttttggtg gaaaattttt agctgttctt ttctttttaa
    10561 tgtgtgaatc tattgtggta gtatctatgg ggttgttttt gggtcttgtt tgtaaaaatt
    10621 tagatatgtt acgtaatatt attaatatac cgatagttat ttttggattc ttaggaggag
    10681 tgttctttcc agttagttca ttgaatccag ttatttcatt aatcattaat atatcaccat
    10741 taacatggat taatagaggc atagttgctt gtatctatga taataattta caactccttt
    10801 ttaatatatc atgcatattt gtagttgtaa gcatatttat gacaatactt acaatcaagt
    10861 tttttaaaaa gggggtcttt atatagtgaa tgtaataaat gtttttaata ttaacttaaa
    10921 aagaaatata aataagagaa tagtattttt agttacactt ttatttccta taattatagt
    10981 aattttggga gtattggcaa attacataag taaaccattt tttaatattg gtattttaga
    11041 tgagtacaaa aacgaacgag ttctaaagga atctgaaaaa agaacctatg aaaatacaat
    11101 aatggcttta gaaaatactc aagggattaa tacaaagatt gcagatttta aaacaattaa
    11161 aactgatatt ataacaggca agtattcagc tgtcatatat tttaataaga atggttttaa
    11221 gttatattct ataaaaaata aaaatacgaa tgatacatta aagtatttaa tagaaacata
    11281 taaaaaagac ccagttcctg tagatataag taaattacaa gaaaatactt taggagtttt
    11341 acaaagaata attgcattta tcgtattatt tttaatgata acatctactg taacagcatc
    11401 aatgattatt aaagataaaa actcaggtac atttacaaga gtgctgtatt ctccacaaaa
    11461 tgtaagagga tatgtgctag ggaatatgtt atacaacttt acaataacgt attttcagta
    11521 catagtttca atatctataa ttaagttatt taatattgat attggtatgg attatataga
    11581 tttaatttta atgggaatat gggtagtagc tttggcaact tcttttggaa catttgtatc
    11641 ttctttattc aatagagaga tgcatgcaaa tttattttct acatgtatat cacttgtatt
    11701 atcacttatt ggaggttcat tcatctcagt tgaaaaaatg ccagaaatgt tgcaaaaaat
    11761 tagtattata agccctgtaa ggtggtttat tagttttgtg acttatatag aagaaagaga
    11821 tggaagcttt tttaatatga attatatttg tattttgacc tctataataa tagttttagc
    11881 tttgttagct atgaaattta ctcaaagaag taaatattca agtaatagta attattaaat
    11941 aagataaaaa ataaatatat gtaattaaaa caaatcaaga gataaaaata taaatatggt
    12001 tctatatctt ataaattggg tttaattata aaaatagaaa ttatatagtg taaaaaatag
    12061 tgtgaaaatt tttttatttt ataatatagt gtcacatgag caaattaaat ttgttctgag
    12121 atagctcttt tttatttatc ttaatagaaa tatttttaat tgttttatat aaagtttatc
    12181 ttctaaataa aattatgtat aacaaataag ggtataaaaa tactattttc tagggacaat
    12241 ttgatagata taaagatctt ttgagacaac atagattaaa atgtattaaa cacttgttaa
    12301 aagtaagaat tgaatattta aaagagaggg gagttttata tgaataattt attttatgat
    12361 aagctaaatt ttgatgataa actaatcatc aaaaataatg gagtaatcag aaataacgac
    12421 ttatattttt taaaatataa aaacgatacg gcaggaatct taatatataa tataataaat
    12481 gataaattct catttaagca aaataaaaat tacaagggaa tgaacccatt tccaatcaca
    12541 aatattttca agaatttaga tagtgataaa tgggatgaat ttataagaat ttggattgag
    12601 gaaagagtta ttcaagaatg cagaccagag gttcctttta tactaaaaga atttaaacta
    12661 ggatattatg acgtttggga tatttgtaga agtaatcttg ctatgagtgt agaagatttt
    12721 ttctggatta caaaagataa cactctaaga tatgaagatt ttaacatccg ttattgtact
    12781 ttaaataata ttactcctat ttataagcct ccttttccta ttgttatata tccaaatta
//
LOCUS       DBGJFK010000169        12684 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.100, whole genome shotgun sequence.
ACCESSION   DBGJFK010000169 DBGJFK010000000
VERSION     DBGJFK010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.100"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            8..1558
                     /locus_tag="ACOIAP_003648"
     CDS             8..1558
                     /locus_tag="ACOIAP_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2640479.1"
                     /translation="MFPHFSITSIFLKKTRVVAYCRVSTGSDEQLVSLQAQKAHYESY
                     IKANPEWEYAGLYYDEGISGTKKENRSDLLRMLSDCETGRIDLIITKSISRFARNTTD
                     CLEMVRKLIDLGVHIYFEKENINTSSMESELMLSILSGLAESESISISENTKWAIQRR
                     FQNGTFKISYPPYGYQNIDGQMIINPKQAEIVKYIFAEVLSGKGTQKVANDLNQKGIP
                     SKRGGRWTATTIRGILTNEKYTGDVILQKTYTDSHFNRHTNYGEKNMYLVENHHEAII
                     SPEDFEAVDAILNQRAKEKGIEKRNSKYLNRYSFSSKIICSECGSTFKRRIHSSGTRK
                     YIAWCCSKHISNITECSMQFIRDEDIKTAFVTMMNKLIFGQKFILRPLFHGLRNQNNA
                     ASFRRIEELETKIENNMEQSQVLTGLMAKGYLEPALFNKEKNALEAERERLLAEKDQL
                     TRSVNGNFAKVDEVDRLLKFATKSKMLTAYEDELFEDYVERIIVFSREEVGFELKCGI
                     TLKERLVN"
     gene            1559..1972
                     /locus_tag="ACOIAP_003649"
     CDS             1559..1972
                     /locus_tag="ACOIAP_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2640480.1"
                     /translation="MGHTPYGYRIEDGKAVVDEKTSEQVKELFSGYLAGLSLKEAAKK
                     AGIDCYHATAGKMLQNKHYLGDEFYPPIIDEETFEKAREEKRKRAEKLGRIREPKDEP
                     KTDYPVKFKAKPLVQKYEDPYKQAEYAYSLIESEV"
     gene            1976..3547
                     /locus_tag="ACOIAP_003650"
     CDS             1976..3547
                     /locus_tag="ACOIAP_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2640481.1"
                     /translation="MAVSRNVTVIPAIKRVGNNKTSESKPKIRVAAYCRVSTDSEEQA
                     SSYEIQIEHYTNYIKKNKEWELAGIFADDGITGTNTKKREEFNRMIEECMAGKIDMII
                     TKSISRFARNTLDCLKYIRQLKDKNIAVFFEKENINTMDSKGEIMLTIMASLAQQESQ
                     SLSQNVKLGIQYRYQQGEVQVNHKRFLGYTKDENKQLVIDPEGAEVVKRIYREYLEGA
                     SLLQISRGLEADGILTAAGKAKWRPETLKKILQNEKYIGDALLQKTYTVDFLSKKRVK
                     NNGIVPQYYVENSHEPIIPRELFMQVQEEMVRRANLRGRKGGKKRVYSSKYALSSIVY
                     CGHCGDIYRRVHWNNRGYKSIVWRCVSRLEEKGSECTAPTINEETLQTAVVKAINELL
                     ANKEPFLSTLQKNIATVFNEENDNATDDIEGKLEELQQQLLIQAKSKNDYEDVADEIY
                     RLRELKQNALAENAEREGKRQRIAEMTDFLNEQSCELEEYDEQLVRRLIEKVTVFDDK
                     LTVEFKSGVEIDIEI"
     gene            3902..4771
                     /locus_tag="ACOIAP_003651"
     CDS             3902..4771
                     /locus_tag="ACOIAP_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGZ2640482.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            4752..5486
                     /locus_tag="ACOIAP_003652"
     CDS             4752..5486
                     /locus_tag="ACOIAP_003652"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGZ2640483.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            5519..6427
                     /locus_tag="ACOIAP_003653"
     CDS             5519..6427
                     /locus_tag="ACOIAP_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGZ2640484.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPAEEKGYSYIILFDDYNKIDLT
                     LLPLEELGNYLNDDKLIKIILDKDGRIQQAVVPTDMDYHIRKPSAREYDDCCNEFWNT
                     TTYVVKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            6424..6966
                     /gene="sat4"
                     /locus_tag="ACOIAP_003654"
     CDS             6424..6966
                     /gene="sat4"
                     /locus_tag="ACOIAP_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HGZ2640485.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            7059..7853
                     /locus_tag="ACOIAP_003655"
                     /note="aph(3')-IIIa"
     CDS             7059..7853
                     /locus_tag="ACOIAP_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HGZ2640486.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            8129..8260
                     /locus_tag="ACOIAP_003656"
                     /pseudo
     CDS             8129..8260
                     /locus_tag="ACOIAP_003656"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            8336..9081
                     /locus_tag="ACOIAP_003657"
                     /pseudo
     CDS             8336..9081
                     /locus_tag="ACOIAP_003657"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            9192..9851
                     /locus_tag="ACOIAP_003658"
     CDS             9192..9851
                     /locus_tag="ACOIAP_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGZ2640487.1"
                     /translation="MKPKIIMHTQISLDGRIKGFDNPEVYYQVAGGIHSDAVLFGSNT
                     VFTAFEKYPAETEADFEKIITSPEDPRPIGVIPDSRGILRSLHCLRNLGYLKEIVILV
                     STATPKEYLNYLEERHYPYIVSGNDHVDYEKAFQILHEQYGCKYMRTDSGGGLTNKLL
                     ENGLIDEISLVISPCFVGNKEKQLFDNLLLSEKVNLELQGTENAEHGCLSLRYAVKNK
                     D"
     gene            10513..10764
                     /locus_tag="ACOIAP_003659"
     CDS             10513..10764
                     /locus_tag="ACOIAP_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGZ2640488.1"
                     /translation="MIHVVKIPVKNKTKEVVRITVYCRVSKNIEEQRSGLNSQIAYFK
                     ELSNKVIEIDLAEVYHDVGRSGLIKNGRTSYKKMIVDGL"
     gene            10883..11254
                     /locus_tag="ACOIAP_003660"
     CDS             10883..11254
                     /locus_tag="ACOIAP_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008818840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640489.1"
                     /translation="MSCHSIGHGLNSVSKKVLELYDEGKIEFSVAKDLLYTTRNAVHY
                     CDGNTYEAIACFDGCRCARCLKKTNELYGLYDALDECREYYDIFSNKEDGVLSGDLCK
                     DCFDEICEKHHSIIIEDEVVY"
     gene            11597..12070
                     /locus_tag="ACOIAP_003661"
     CDS             11597..12070
                     /locus_tag="ACOIAP_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640490.1"
                     /translation="MNWSFSDKMFVYFINDLEMYSKWEYSGESELLMLEYKEGILSFD
                     NIMQFYLDKMMRDKVIDSIPSFFQQLLRICKKFKALKDISNAFGRDKLIQVTKENILI
                     IFHQVWQRYLYRENISVFKTMENELYTIFKGMKWNSFMNKIKVFVQKPEVKYINL"
BASE COUNT         4420 a         1901 c         2789 g         3574 t
ORIGIN      
        1 ctgtataatg tttccacatt tcagcataac gtccattttt ttaaaaaaaa cacgagtagt
       61 tgcctactgt cgagtttcta caggcagtga tgaacaactt gtcagcttgc aagcacaaaa
      121 ggcccattat gagagctata taaaggctaa tccagaatgg gaatacgcag gcttatatta
      181 tgacgagggt atcagcggca cgaaaaagga aaaccgctct gacctactta gaatgttatc
      241 agactgtgaa actgggagaa ttgacttaat tattacaaag tcaattagcc gatttgccag
      301 aaatactaca gattgcttgg agatggttcg aaaactgatc gaccttgggg ttcatatcta
      361 ttttgagaag gaaaacatca atacgagttc aatggagagc gaattgatgc tctccatttt
      421 aagtgggctt gcagaaagtg agtcaatttc catttccgaa aatacgaagt gggccattca
      481 aagacgattc caaaacggaa cctttaaaat ttcctaccca ccatatgggt atcaaaacat
      541 tgacggtcag atgataataa accccaagca agctgaaatt gtgaagtata tttttgcaga
      601 ggtattatcg ggcaaaggca cacagaaagt tgcaaatgat cttaatcaaa agggtatccc
      661 ttcaaaaaga ggtggtcgtt ggacagctac tacgattaga gggattctga ccaatgaaaa
      721 atatactggc gatgttattt tgcaaaagac ttatactgat agccatttta acaggcacac
      781 caattatggt gaaaaaaata tgtatctagt agaaaaccac catgaggcaa ttatcagccc
      841 tgaagatttt gaagctgtag atgccattct caatcagaga gccaaggaaa aaggaatcga
      901 aaaacgcaac agtaaatatc taaaccgata ttccttttct agcaaaatta tctgctcgga
      961 atgtggcagt acctttaaaa gacggattca ttcatctggt acaagaaaat acattgcttg
     1021 gtgctgcagt aagcatatca gcaatataac ggaatgttcc atgcagttca ttcgagatga
     1081 agatataaag actgcatttg ttacgatgat gaataaactc atattcggtc agaagtttat
     1141 attaagacca ctttttcatg ggttacgtaa ccaaaacaat gcagcgagtt ttcgtagaat
     1201 tgaagagttg gaaactaaaa ttgaaaacaa catggagcag agccaagtac tgacaggttt
     1261 aatggccaaa gggtatctgg aacctgctct gtttaataaa gaaaagaatg cactggaggc
     1321 agaaagagaa aggcttcttg ccgaaaagga tcaacttact cgttccgtca atggcaattt
     1381 tgctaaagta gatgaagttg accgtctgct taagtttgcc actaagtcca aaatgctcac
     1441 agcttatgag gatgagttgt ttgaagatta cgtagagagg attattgtct tttcacggga
     1501 ggaagtaggt tttgaattaa aatgtggaat cacattgaag gaaaggttgg tgaattagat
     1561 gggtcacaca ccctatggat atagaattga agatggaaaa gctgttgtgg atgaaaagac
     1621 ttctgagcag gtaaaagaat tattttccgg atacttggca ggcctttctt tgaaggaagc
     1681 tgctaaaaaa gctgggatag attgttatca tgccacagca ggtaagatgt tgcagaacaa
     1741 gcactaccta ggcgatgaat tttaccctcc cattattgat gaggagacat ttgaaaaagc
     1801 cagagaagaa aaacgaaaac gagcagaaaa gctcgggagg ataagggaac ctaaagatga
     1861 accgaaaacg gattaccctg taaagttcaa agcaaaacct ctggtgcaaa aatatgaaga
     1921 cccatacaag caggcggaat atgcctacag tttgatagaa agtgaggtgt aacaagtggc
     1981 agtgagtaga aatgtcacag tgattccggc aattaaacga gtcggaaata ataaaactag
     2041 tgagagcaaa cccaaaatac gagtggctgc ttactgtcgt gtttcaacgg atagtgagga
     2101 gcaggcttca agttatgaaa ttcagattga acattataca aactatatta agaaaaacaa
     2161 ggaatgggaa ttggcaggga tttttgcgga tgatggtatc acaggtacaa ataccaaaaa
     2221 gcgtgaagag ttcaaccgca tgattgagga atgtatggca ggaaaaatag acatgatcat
     2281 tacaaaatcc atcagccgat ttgccagaaa cacgttagac tgccttaaat acatccgtca
     2341 gttaaaagat aaaaacatcg ctgtattctt tgaaaaagaa aatatcaaca ccatggattc
     2401 caagggtgaa attatgctga ctattatggc ttcccttgcc caacaggaaa gccaatcctt
     2461 aagtcagaac gttaagctgg gcattcagta tcgatatcaa caaggtgaag tccaggtcaa
     2521 ccataagcgt ttccttggat acaccaagga tgaaaacaag caactagtca tcgaccccga
     2581 gggtgcagag gttgttaaac ggatttatag agagtacctt gaaggagcta gtcttttaca
     2641 aatatcaaga ggactagaag cagacggtat tcttacagcg gcaggcaaag ccaaatggag
     2701 accagaaaca ctaaaaaaga tattgcagaa tgaaaagtac atcggtgatg cccttctaca
     2761 aaagacatat acggttgatt tcctttctaa aaagcgggtc aagaataacg gcatcgttcc
     2821 ccagtattat gtagaaaaca gccatgagcc gattattcca agggagcttt ttatgcaagt
     2881 tcaagaagag atggttcgaa gagcaaatct tcgtggccgc aaaggcggta aaaagcgagt
     2941 ctatagcagc aagtatgctt tatcgagtat tgtttactgc ggacactgcg gcgatattta
     3001 ccgacgggta cattggaata acagaggcta caagtctatt gtttggagat gtgttagccg
     3061 attggaggaa aaagggtctg aatgcactgc tcctaccata aacgaggaaa cattgcagac
     3121 agcagtggtc aaggctatta acgagctttt ggctaacaaa gaacccttcc tctcaacctt
     3181 gcagaaaaac atagctactg tatttaatga agaaaatgat aatgccaccg atgatattga
     3241 aggcaaattg gaagaattac aacaacagct tcttatacaa gcaaagtcca agaatgacta
     3301 tgaagatgtg gctgatgaaa tttaccgcct tcgagaattg aagcaaaatg cacttgcaga
     3361 gaatgcagag cgtgaaggaa aaaggcaacg aatcgctgaa atgactgatt tcttaaatga
     3421 acaatcctgc gagttggagg aatatgatga gcaattagta aggcggctta ttgaaaaagt
     3481 tacggtattt gatgataagc tcactgttga atttaaatca ggtgttgaaa tagatattga
     3541 gatataggat atcagaaatg gcgaccaatt gagaggtgtt acttccttga ttggtggctt
     3601 ttcttattta cggattgact ttgactgtga atatacgtat aataatatca acaatgttgt
     3661 tgatattatt attaataagg agtggacaac atgattgatg taaatgagct attttagcaa
     3721 aatgaatggt aatttaaagg ctattgaaaa gacttcatct aatcagcaga ggtataaaaa
     3781 gacaattgat aagttttaac tatcttttgt gaaattaaaa aaattataaa tatgttgagt
     3841 agaagcaaaa gatttggctt ggaattttta cagcagtgaa tcgataaaag gagcatgctt
     3901 gatggtagat aatattatta aatcagtagc agagaaatta tcctctctgt cttatataga
     3961 aggtattgtt ttaggtggtt cacgtgcaag gggcacccat acagaggatt cggatataga
     4021 tatcggcatc tattacaatt cagaatcatt tgacataaat actattaatc aattcgctac
     4081 aaagctggat gatgagcata gaaataacct tgttgtacct cccggagcat ggggtgattg
     4141 gattaatggc ggcggatggt tagtcataaa cgggtatcat gtggatttaa ttttacgtga
     4201 tattaaacgt gtggaacaaa taatgaaaga tacagagcac ggaattgtta ctgccaatta
     4261 tcagactggg catccccatg gttatattag tgcaatgtat cgaggagaat tagcgattag
     4321 caaaatacta tatgctaaga atgaaagctt atgcgaatta aaaaaacagg cagaaactta
     4381 tcccaatgct ttgcagaaaa gtttagttaa cttttttatg tttgaagcag ggttctcttt
     4441 aatgtttgta aaagcaaatt cgggaacaga cgataaatat tatattgcgg gtcatgtttt
     4501 tcgtatagtt tcatgtttaa atcaagtgtt atttgcatgt aataatgctt attgtatcaa
     4561 cgaaaagaaa gctataaaac tgcttgaaac ttttgaacat aaacctgaaa aatataccga
     4621 gaaggtaaat catatttttg aagtactcgg tatctcactt tttgaatgct acgacatgac
     4681 cgagaagctt tataatgaag tgaatgaaat tgtatcggag ataaataact ttttaaacga
     4741 ggagagttca gatgaaagaa aacaaatatg atgataatat attttttcaa aaatacagtc
     4801 aaatgagtcg ctcgcagaaa ggactggctg gtgcgggaga atgggagact ttgaaaaaga
     4861 tgctacctga ttttaagggt aagcgtgtgc ttgatttagg atgcggctat ggatggcact
     4921 gtatatatgc gatggaaaac ggtgcttcct ctgtagtagg tgttgatatt tctcataaaa
     4981 tgctcgaagt agcaaaagga aaaacccatt ttccacagat tgaatatgaa tgctgtgcca
     5041 tagaagatgt ggatttccca gaggagagct ttgatgtaat actaagttcg cttgcgtttc
     5101 attatgtagc agactatgag aatttaataa aaaagatata taggatgctg aaggctggtg
     5161 gcaatttagt ttttacagtt gaacatcctg tttttactgc tcatggaaca caagactggt
     5221 attataacga aaaaggagaa atactgcatt tcccggtgga caattattat tatgagggca
     5281 aacggacagc tatgtttttg gaagaaaagg ttacaaaata tcatagaaca ctgaccacat
     5341 atctaaatac actgctttca aatagtttta taataaatca gattgtggag ccacagccgc
     5401 cagagaacat gatggatatt ccggggatgg cggatgaaat gcgacgccca atgatgctga
     5461 ttgtatcggc aaaaaagaag atgtaataat atagaaaaaa taaacgagga gtatgtaaat
     5521 gagatcagaa aaagaaatga tggatttagt actttcttta gcagaacagg atgaacgtat
     5581 tcgaattgtg acccttgagg ggtcacgcgc aaatattaat atacctaaag atgaatttca
     5641 ggattatgat attacatatt ttgtaagtga tatagaaccg tttatatcta atgatgactg
     5701 gcttaatcaa tttgggaata ttataatgat gcaaaaaccg gaggatatgg aactattccc
     5761 ggctgaagag aaaggctact cctatataat actttttgat gattataata aaatagacct
     5821 taccttattg cccctggaag agttgggaaa ctacctgaat gacgataaat tgataaagat
     5881 tattctggat aaggatggaa ggattcagca agctgtagtt ccgaccgaca tggattatca
     5941 tataagaaaa cccagtgccc gggaatacga tgactgctgc aatgaattct ggaacaccac
     6001 tacctatgtg gttaagggac tgtgccgtaa ggaaatttta tttgctattg atcattttaa
     6061 tcagattgtt cgccatgagc tgctgagaat gatatcatgg aaggtcggca tcgaaacagg
     6121 ctttaaatta agtgtaggca agaactataa gtttattgaa aggtatatat ccgaggattt
     6181 gtgggagaaa cttttgtcca cctaccggat ggattcctat gaaaacatat gggaagcatt
     6241 atttctatgc catcaattgt tcagggcggt atccggtgag gtggcggaaa ggcttcatta
     6301 tgcctatccg gagtatgata ggaatataac aaaatatacc agggacatgt ataaaaaata
     6361 cactggtaaa accggctgcc tggatagcac atatgccgct gatatagaag agaggcggga
     6421 acagtgatta cagaaatgaa agcagggcac ctgaaagata tcgataaacc cagcgaacca
     6481 tttgaggtga taggtaagat tataccgagg tatgaaaacg agaattggac ctttacagaa
     6541 ttactctatg aagcgccata tttaaaaagc taccaagacg aagaggatga agaggatgag
     6601 gaggcagatt gccttgaata tattgacaat actgataaga taatatatct ttactaccaa
     6661 gacgataaat gcgtcggaaa agttaaactg cgaaaaaatt ggaaccggta cgcttatata
     6721 gaagatatcg ccgtatgtaa ggatttcagg gggcaaggca taggcagcgc gcttatcaat
     6781 atatctatag aatgggcaaa gcataaaaac ttgcatggac taatgcttga aacccaggac
     6841 aataacctta tagcttgtaa attctatcat aattgtggtt tcaaaatcgg ctccgtcgat
     6901 actatgttat acgccaactt tgaaaacaac tttgaaaaag ctgttttctg gtatttaagg
     6961 ttttagaatg caaggaacag tgaattggag ttcgtcttgt tataattagc ttcttggggt
     7021 atctttaaat actgtagaaa agaggaagga aataataaat ggctaaaatg agaatatcac
     7081 cggaattgaa aaaactgatc gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc
     7141 ctgctaaggt atataagctg gtgggagaaa atgaaaacct atatttaaaa atgacggaca
     7201 gccggtataa agggaccacc tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg
     7261 aaggaaagct gcctgttcca aaggtcctgc actttgaacg gcatgatggc tggagcaatc
     7321 tgctcatgag tgaggccgat ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc
     7381 ctgaaaagat tatcgagctg tatgcggagt gcatcaggct ctttcactcc atcgacatat
     7441 cggattgtcc ctatacgaat agcttagaca gccgcttagc cgaattggat tacttactga
     7501 ataacgatct ggccgatgtg gattgcgaaa actgggaaga agacactcca tttaaagatc
     7561 cgcgcgagct gtatgatttt ttaaagacgg aaaagcccga agaggaactt gtcttttccc
     7621 acggcgacct gggagacagc aacatctttg tgaaagatgg caaagtaagt ggctttattg
     7681 atcttgggag aagcggcagg gcggacaagt ggtatgacat tgccttctgc gtccggtcga
     7741 tcagggagga tatcggggaa gaacagtatg tcgagctatt ttttgactta ctggggatca
     7801 agcctgattg ggagaaaata aaatattata ttttactgga tgaattgttt tagtacctag
     7861 atttagatgt ctaaaaagct ttaactacaa gctttttaga catctaatct tttctgaagt
     7921 acatccgcaa ctgtccatac tctgatgttt tatatctttt ctaaaagttc gctagataga
     7981 gttctatatt agagatgtaa agagttttgg tgaagaggtt tgtgagtatg gcttttataa
     8041 ccagggtgca atgagaagca ctaacagcag ctagcttaag aacgcatagg atatactttt
     8101 tatggaagtc acagaggagg aataaaattt gaacaggatt aacagagtaa cctctattct
     8161 tattcagctg caatcaaaaa aaataattcc tgccaaagaa attgcacagc gatttaatat
     8221 aagcttaagg acagtttaca gagatatccg gacacttgaa gaagccggaa taccaattgg
     8281 atctgaggcc ggaaaaggat attttcttgt agagggcttc ctacttccgc cggtaatgtt
     8341 tacagcggcg gaagtgggtg cattgattac agcagggaaa tttttaaatt gccatggaga
     8401 tgaatcattt ataaaggatt ttgattcagc tatgtataaa atcaaatcta ttttgaagca
     8461 tggtgaaaaa aactatgcac aggagttgga gaacagtatt aacgtgtaca gcacatctgg
     8521 acagaaaaat acattggcgg ataacgttat tgcagcaatt cagactgcaa tctgcaataa
     8581 aagggtaata tcaattcaat atcctgcatc aggagggcaa gaaccggaaa gcagaatgat
     8641 agagcctata tcactggggt tttatgaaca gaactggtac ttaatcggtt ttgcaggcta
     8701 agaaatgaat ataggaattt tcgtgtggat cggattaaaa gcatttgcat agaagaagag
     8761 ctctgtcaaa gccatgatgg ctctttggaa caaatattaa aacaaatgct ttcatataaa
     8821 aaactatata atgtaattct tagagctgaa aaaggggaga catacaattc tatcaagaac
     8881 aggtattctc tcggcttcct tgaagaaacc gatttgggaa gtaaaatgga aatcgaattc
     8941 cagacagatt cctttgagat attgagcaag cagctgattg aatatggatc aggcattgaa
     9001 atagtccaac ctgatgaatt aaaatgcata acccgtaaac acctggcaca aattacgaat
     9061 cactgcctaa acttgattta gagaaagcga ttggtctgtt atgtattttt tgtaaggttt
     9121 catatcccct gctgacatac agctgtcagt gtattatgat attctactat caaaaaggag
     9181 gattgaaaaa tatgaaacca aagataatta tgcacacaca aattagcctt gatggccgca
     9241 ttaaaggctt tgataatccg gaagtttact accaggttgc cgggggaatt cattcggatg
     9301 cggtgctgtt tgggtccaat actgttttta ctgcatttga aaaatatcct gctgaaacag
     9361 aggctgattt tgagaaaatc ataacaagcc cggaggaccc cagaccaata ggagtcatac
     9421 ctgacagcag aggtatcttg agaagtcttc attgcttaag aaatcttgga tatctgaagg
     9481 aaattgtcat tctggtatca actgccactc cgaaggaata tttgaattat ttggaggaaa
     9541 ggcattaccc atatattgtg tcaggaaatg atcatgtgga ctatgaaaaa gcctttcaga
     9601 tcctgcatga gcaatatggg tgtaaataca tgcggacaga cagtggcggt ggattaacca
     9661 acaaattatt agaaaacgga cttattgatg aaatcagtct tgtgatatca ccatgttttg
     9721 taggtaataa agaaaaacaa ctatttgata accttctgtt atctgaaaaa gttaatttgg
     9781 aattgcaggg aacagagaat gcagaacatg gctgtctgtc attgcgctat gctgtgaaaa
     9841 ataaggatta gtgcagcata ctttaaaaag tgtctgttgg gacagtgtcc taaaggaagc
     9901 ataagctcat ggctagcggc ggtgttaaag taacggcact cggccccaat atatagttga
     9961 tatgccccta agcctttgag ggcaaggcgg tcaaccgcgc cttttccggt ccgcatacag
    10021 tcgttcaatg agggtatcaa gctcggcaat gcggcggtgc ttctcggtgg ttcgtttctt
    10081 cgccgccgtt ttcggctaat tctaattgat ccgaactgta aggataagca attatccggg
    10141 gctagttaag tatcttagag aggaagataa agataagtaa accaatttta aagttgtacc
    10201 gaataaagcc ttcaagagga caacatgctt ttgaaggctt tattgcttac aattacttgg
    10261 attgtaacgc aaaagcaggc accaaatcaa tgaaaaatag cctatccagg cgactgtttc
    10321 agaaatatgg gcttccgcca aggggatacc agtggggtgc gacatctttt ttgcccactc
    10381 aaggcatgta gagtccattg ttctgttgcg aaaaagataa aaaatcaaat cagttttata
    10441 gagatgtaag ttgttgatga taacttgcat ctttttcata tgttaagatt ggagtgataa
    10501 ggatgataaa aaatgataca tgtagtgaag ataccagtta aaaataaaac gaaagaagta
    10561 gtaagaatta cagtatattg tagagtaagt aaaaatatag aagaacaacg ttcaggttta
    10621 aatagtcaaa ttgcatattt taaagaactt tctaacaaag taatagaaat cgatttagct
    10681 gaagtgtatc acgatgttgg aagaagtggg ttaataaaga atggaagaac aagctataaa
    10741 aaaatgattg tagatggatt ataaggcaaa tttgattaca ttattacaaa atcagttagt
    10801 aggtttataa taaagcattg tagtaaaata aaaaaatatg atatatttag attagtgata
    10861 ataaaaaaaa ggagctaaaa atatgagttg tcatagtatt gggcatggat taaattcagt
    10921 gtctaaaaag gtattagagt tgtatgatga agggaaaatt gaatttagtg ttgcgaaaga
    10981 tttattatac accacaagaa atgctgtaca ttattgtgat ggaaatacgt atgaagcgat
    11041 tgcatgtttt gatggatgta gatgtgctag atgtttaaag aaaacaaatg agttatatgg
    11101 tctttatgat gcattagatg agtgtagaga gtattatgat atttttagca ataaagaaga
    11161 tggagtatta tctggtgatc tttgtaagga ttgttttgat gaaatttgtg aaaaacacca
    11221 ttcgattatc atagaagacg aagttgtata ttaaaaaagt tttactcgat aatgggtaaa
    11281 tcttcaactt ttagcggaat tattagcaga tagtaataat atacctatga tatttgtgaa
    11341 gtttaatctt atattttcaa taagggatta ctatacacat tgcttatctc ttttaatctt
    11401 tgattcacgt tgagagtgtt gtcttgatgt caagggttca gaagtaacat gtgaaaaagg
    11461 cttgaaaata ggtcatttta aaaatagatt gtaattttta agtacattga aatcacgaaa
    11521 atgcttgtaa atcagggcat ggaaacatat caatacggac agtggagttg acagagtagt
    11581 aaccaaaatt gaaggtgtga actggtcttt tagcgataaa atgtttgtct actttataaa
    11641 tgatttagag atgtatagta agtgggaata ttcaggtgaa agtgagttgc ttatgttgga
    11701 atataaagag ggcatactat cttttgataa tataatgcaa ttctatttag ataaaatgat
    11761 gcgggataag gttattgatt caattccttc attttttcag cagttactta gaatctgtaa
    11821 aaagtttaaa gcattaaaag acattagtaa cgcatttgga agggataaat taatccaagt
    11881 aactaaagaa aatattttaa taatattcca tcaagtctgg caaaggtatt tatacaggga
    11941 aaatatttct gtattcaaaa ctatggaaaa tgagctgtat acaattttca aaggaatgaa
    12001 atggaacagt tttatgaata aaataaaagt attcgttcag aagccggaag taaaatatat
    12061 caatctgtaa cctttgcaat ggtggaagca tattggaata aggataaaag tattatagat
    12121 aagcagggtt gagaggaaga gtctgagtat ggaccagatt aatagttgaa ctatctaaac
    12181 ataaattggc agatttcgga atagaattta ctattgtaaa tctttaaaat atgcgtcagt
    12241 tttatcttgc ttttccaaaa actacgtatt gtgtcgcgaa ttgagttgga cacattatcg
    12301 cttgcctatg cgagtggaga aaccccgtga attttaacga ataaatttac tccaccatta
    12361 tgtaatgaaa atacttttgt catggtgtat aaggccttta ttttactgta tgtggagtca
    12421 tagcattgct atgtagagtt gaaaagcctg ataaacaaag gctttctttt atttatgtct
    12481 actcaaaaat actgctttca tttgtatttt aataaaaaat tatgttatgc tcgatatgga
    12541 ataaaaaaca catttaaaat ggaataggag aatgtcaaga tgaagattaa tataagtacc
    12601 attatagagg cgattgaaat ggcagatgat aattttacat tttttttatc tgataaaaat
    12661 aatatttctt ttaatttttt catt
//
LOCUS       DBGJFK010000170        11479 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.104, whole genome shotgun sequence.
ACCESSION   DBGJFK010000170 DBGJFK010000000
VERSION     DBGJFK010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11479
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.104"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            <1..1085
                     /locus_tag="ACOIAP_003662"
     CDS             <1..1085
                     /locus_tag="ACOIAP_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGZ2640491.1"
                     /translation="GVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVD
                     PKAERGRWKETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLT
                     GISSRDGERFPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDF
                     AHLLFSNGYVEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFA
                     LDFIHTDRSIFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLD
                     EKLKNNLGLKFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRV
                     GVIQFHPVFEELLHAFDTRPPVRKEV"
     gene            1088..3265
                     /locus_tag="ACOIAP_003663"
     CDS             1088..3265
                     /locus_tag="ACOIAP_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGZ2640492.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            3262..4263
                     /locus_tag="ACOIAP_003664"
     CDS             3262..4263
                     /locus_tag="ACOIAP_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HGZ2640493.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            4260..5192
                     /locus_tag="ACOIAP_003665"
     CDS             4260..5192
                     /locus_tag="ACOIAP_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGZ2640494.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            5437..5553
                     /locus_tag="ACOIAP_003666"
     CDS             5437..5553
                     /locus_tag="ACOIAP_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HGZ2640495.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            5569..7488
                     /gene="tet(M)"
                     /locus_tag="ACOIAP_003667"
     CDS             5569..7488
                     /gene="tet(M)"
                     /locus_tag="ACOIAP_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HGZ2640496.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNVCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            7607..7774
                     /locus_tag="ACOIAP_003668"
     CDS             7607..7774
                     /locus_tag="ACOIAP_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HGZ2640497.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(7834..8187)
                     /locus_tag="ACOIAP_003669"
     CDS             complement(7834..8187)
                     /locus_tag="ACOIAP_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2640498.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            8692..9114
                     /locus_tag="ACOIAP_003670"
     CDS             8692..9114
                     /locus_tag="ACOIAP_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGZ2640499.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            9111..9341
                     /locus_tag="ACOIAP_003671"
     CDS             9111..9341
                     /locus_tag="ACOIAP_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGZ2640500.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            complement(9567..9818)
                     /locus_tag="ACOIAP_003672"
     CDS             complement(9567..9818)
                     /locus_tag="ACOIAP_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640501.1"
                     /translation="MSVCFIKSSFPNHLFGFHKSCFTSNRTALAKLTGVPPLHGSHVA
                     ILIACDGFITLGLLTVWEYHYHDKNVVAGNPAKDCFSDH"
     gene            9802..10005
                     /locus_tag="ACOIAP_003673"
     CDS             9802..10005
                     /locus_tag="ACOIAP_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGZ2640502.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            10087..11304
                     /locus_tag="ACOIAP_003674"
     CDS             10087..11304
                     /locus_tag="ACOIAP_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGZ2640503.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3804 a         2033 c         2357 g         3285 t
ORIGIN      
        1 aaggggttaa gggttcagta accaatgcgt tagcgtcggc ttttgttggt tcgctgggtg
       61 gtggtaaatc ctttgcgaat aaccttatcg tctattatgc ggtgctttat ggggcacaag
      121 cagtgattgt agacccaaaa gcagaacgtg gcagatggaa agaaaccttg ccagagattt
      181 cccatgaaat caatatcgtc actctgactt ctgatgagaa aaacaaaggc ttacttgacc
      241 cttatgtgat tatgaaaaat cccaaagatt ctgaatcact ggctattgat attctgacat
      301 tccttacggg gatttcctct cgtgatgggg aacgcttccc aatccttaga aaagccattc
      361 gtgcagtaac caatagtgaa gtacgagggt tgatgaaagt gattgaggaa ttacgggttg
      421 agaatacgcc actaagtacc agtatagccg accatatcga aagttttaca gactatgact
      481 ttgcacattt attattcagt aatggttatg tggagcagtc tatcagctta gaaaaacaac
      541 tgaacattat acaggttgcg gacttggtac ttcccgacaa ggaaacttcc tttgaggaat
      601 ataccactat ggagctttta tccgttgcta tgctgattgt cattagtacc tttgctttag
      661 actttatcca tacagaccga agcattttca agattgtaga tttagacgaa gcatggagct
      721 ttttacaggt agcacaagga aaaacactat ctatgaagct ggttcgggct ggtcgtgcta
      781 tgaacgctgg ggtatatttc gtgacccaaa atacagacga cctcttagat gaaaaactga
      841 aaaataacct cggcttaaaa tttgcatttc gttccactga ccttaacgag attaaaaaga
      901 ccttagcctt ttttggtgta gacccagagg acgaaaacaa tcagaagcga ttgcgtgatt
      961 tggaaaacgg gcaatgcctt atcagtgatt tatatggtcg tgtcggtgtg atacagttcc
     1021 accctgtatt tgaagaactg ctccatgcct ttgataccag accacctgtg cgaaaagagg
     1081 tgtaaatgtg aaaccatcaa tagtaaacag aataaaatca aactggacgc tgaaacgtct
     1141 aggtaaagtg gcaatgacag tggctttcac acttgtgatt gccatttttc ttttagccat
     1201 gctgggaacg gtggttcaag ctgcgggctt ggtagatgat acggtcaatg tggcaaatga
     1261 atacagccga tacccacttg aaaactatca actggatttt tatgtggata atagctgggg
     1321 ctggcttccg tggaactggt cggacgggat tggaaaacag gtcatgtatg gactatatgc
     1381 cattaccaat tttatttgga caatcagttt gtatgtttcc aatgcgacag gttacttagt
     1441 acaggaagcc tattccttag acttcatttc cgctacagca gattccattg gtaagaatat
     1501 gcagacctta gctggtgtga gtgcaaacgg attttcaaca gagggtttct atgttggatt
     1561 cctcttactc ttgattttgg ttcttggggt ttatgttgcc tatacgggac tgataaagag
     1621 agaaaccaca aaggcaattc atgccattat gaattttgtg ctggtgttta tcctatcggc
     1681 ttcctttatt gcctacgctc ccgactacat taaaaaaatc aatgactttt catcagacat
     1741 cagtaatgcc agtttatcac ttggcacgaa gattgtcatg ccccattccg atagtcaagg
     1801 caaggacagc gtggacttaa tcagagatag cctgttttcc atacaggttc agcaaccgtg
     1861 gctactgctt caatacaaca gttcagacat tgaaagtatc ggtattgacc gtgtggaaag
     1921 cctgctctcc accagcccag attccaacaa tggcgaagac agagaaaaaa ttgttgcgga
     1981 agaaattgaa gacagaagca ataccaatct aaccattaca aagaccatta accgtttagg
     2041 tacagtcttc ttcctatttg tcttcaatat tgggatttcc atatttgtat tcctattaac
     2101 aggaatcatg attttctcgc aggtactttt tatcatctat gctatgtttc tgcctgtgag
     2161 ctttatttta agcatgattc catcatttga tggtatgtca aaacgagcca taacaaagct
     2221 ctttaatacc attttgacac gagctggaat cacattgatt attacgacag catttagtat
     2281 ttcaaccatg ctctatacct tatcggctgg ttatccgttc tttttgattg cttttctaca
     2341 gattgtgacc tttgcaggaa tctacttcaa gctgggcgat ttaatgagta tgttttctct
     2401 acagagtaac gattctcaaa gtgtgggaag tcgtgtgatg agaaaacctc gtatgcttat
     2461 gcacgctcac atgcaccgtc tacagcggaa acttggacgt tccatgacta ctctaggggc
     2521 tgggtctgcc attgttacag gtaaaaaagg acagtcgggt tcggggagtt ctgcaaggac
     2581 acaagcagat cactcccgac cagacggaaa ggaaaaatca acacttggaa aacgtatcgg
     2641 tcaaaccatc ggtacagtag ctgataccaa agacagaatg gtagacactg ctagtggttt
     2701 gaaagaacag gttaaagatt tgccgaccaa tgcaagatat gcagtatatc aaggaaaatc
     2761 caaagtaaaa gagaatgtcc gtgatttaac cagtagtatt tctcaaacca aagcggacag
     2821 agccagtgga cgcaaggaac agcaggaaca aaggcgaaaa accattgcga agcgtcgctc
     2881 tgaaatggaa caggtcaaac agaaaaaaca gcctgcttct tctgttcatg aaagaccgac
     2941 tacaagacaa gaacaatatc atgatgaaca gacctcaaaa cagtctaata ttcagacttc
     3001 atataaggaa tctcaacaag ccaaacaaga gcgtccagca gttaagtccg atttttcaag
     3061 tccaaaagtg gaacgccaag gcaataccgt tcaagaaaaa accgttcaaa agccagcaac
     3121 ttcaaccact acagcagata gaacttcaca acgtccaatc acaaaagaac gtccgtctac
     3181 tgttcaaaga gtaccactac aaaatacaag aagtagacca ccaatcaaaa ccgccaccat
     3241 taagaaagtc ggtaagaaac catgaagttg aaaactttag tgattggtgg ttctggatta
     3301 ttcttgatgg tcttctcact gcttctgttt gttgccattt tattttcaga tgaacaggac
     3361 agcggaattt ccaatattca ttatggaggt gtgaatgttt ccgcagaagt gctggctcat
     3421 aagcctatgg tagaaaaata tgccaaagaa tatggcgttg aagaatatgt caacatactt
     3481 cttgcgatta tacaggtgga atcgggcggt actgcggaag atgttatgca gtcctcggaa
     3541 tccctcggtc ttccacctaa ttcattgagt acagaagaat ccattaagca aggtgtgaag
     3601 tatttcagtg aattattagc cagtagcgaa aggctcagtg tagatttaga atcggttatc
     3661 cagtcctaca attatggtgg tggtttctta gggtatgtgg ctaatcgtgg aaataaatat
     3721 acctttgaac tggctcaaag tttctcaaaa gagtattcag gtggcgaaaa agtgtcttac
     3781 cccaatccca tagccatacc tatcaatggg ggctggcgat acaactatgg caatatgttt
     3841 tatgtgcaac tggtaacgca gtatcttgtc acaacagagt ttgatgatga tacggtacaa
     3901 gccatcatgg acgaagcact gaaatatgag ggctggcgat acgtttacgg tggagcttcc
     3961 ccgactactt cttttgattg tagcggactg acacaatgga cgtatggaaa agctggaatt
     4021 aacttaccac gaaccgcaca acagcaatat gatgtgaccc agcatatccc actatcggaa
     4081 gcacaagctg gcgatttggt tttctttcat tctacctata acgctggctc ttatattact
     4141 catgttggga tataccttgg caataaccgt atgtttcatg caggcgaccc aatcggttat
     4201 gccgacttaa caagccccta ctggcaacag catttagtgg gagcaggacg aatcaaacaa
     4261 tgagaaagga agatttaatg atgaaattta gaaaaaatca gaataaagaa aaacagatac
     4321 caaaggaaaa gaaacctcgt gtctataagg tcaatcctca taaaaaggtt gtgattgcct
     4381 tgtgggtact tttagggctt agtttcagct ttgcgatatt caagcacttt acagctatag
     4441 atactcatac tattcacgaa acaactatca tagaaaagga atacgttgat actcatcatg
     4501 tagaaaattt tgtagagaac tttgcgaaag tctactattc atgggagcaa tccgataagt
     4561 ccattgataa tcgaatggaa agtctaaaag gctatctgac agatgaactt caagctctca
     4621 atgttgatac agtacgcaaa gatattcctg tatcgtcttc tgtaagagga tttcagatat
     4681 ggacggtaga gccaactggc gacaatgagt ttaatgtaac ctacagtgta gaccagctca
     4741 ttacagaggg agaaaataca aagaccgtcc actctgctta tatagtgagt gtctatgtag
     4801 atggttctgg aaatatggta ctggttaaga atccgaccat taccaacata cctaagaaat
     4861 caagttataa accaaaagcc attgaaagtg aggggacggt tgattccatt acaaccaatg
     4921 aaatcaatga gtttttaacg acgttcttca agctctatcc tacagcgaca gccagtgaac
     4981 tttcctacta tgtgaatgac gggatattaa aaccaatcgg aaaagagtac atctttcaag
     5041 aactggtaaa tcctattcac aatcgtaagg ataatcaagt cacggtatcg ctgacagtgg
     5101 agtatatcga ccagcagacc aaagcaacgc aggtatctca atttgatttg gtacttgaaa
     5161 agaacgggag taattggaag attatagaat aacaaatatt ggtacattat tacagctatt
     5221 ttgtaatcac gtactctctt tgataaaaaa ttggagattc ctttacaaat atgctcttac
     5281 gtgctattat ttaagtatct atttaaaagg agttaataaa tatgcggcaa ggtattctta
     5341 aataaactgt caatttgata gcgggaacaa ataattggat gtcctttttt aggagggctt
     5401 agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta tccggagaat
     5461 atctgtatgc tttgtatgcc tatggttatg cataaaaatc ccagtgataa gagtatttat
     5521 cactgggatt tttatgccct tttgggcttt tgaatggagg aaaatcacat gaaaattatt
     5581 aatattggag ttttagctca tgttgatgca ggaaaaacta ccttaacaga aagcttatta
     5641 tataacagtg gagcgattac agaattagga agcgtggaca aaggtacaac gaggacggat
     5701 aatacgcttt tagaacgtca gagaggaatt acaattcaga caggaataac ctcttttcag
     5761 tgggaaaata cgaaggtgaa catcatagac acgccaggac atatggattt cttagcagaa
     5821 gtatatcgtt cattatcagt tttagatggg gcaattctac tgatttctgc aaaagatggc
     5881 gtacaagcac aaactcgtat attatttcat gcacttagga aaatggggat tcccacaatc
     5941 ttttttatca ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt
     6001 aaagagaaac tttctgccga aattgtaatc aaacagaagg tagaactgta tcctaatgtg
     6061 tgtgtgacga actttaccga atctgaacaa tgggatacgg taatagaggg aaacgatgac
     6121 cttttagaga aatatatgtc cggtaaatca ttagaagcat tggaactcga acaagaggaa
     6181 agcataagat ttcagaattg ttctctgttc cctctttatc atggaagtgc aaaaagtaat
     6241 atagggattg ataaccttat agaagttatt actaataaat tttattcatc aacacatcga
     6301 ggtccgtctg aactttgcgg aaatgttttc aaaattgaat atacaaaaaa aagacaacgt
     6361 cttgcatata tacgccttta tagtggagta ctacatttac gagattcggt tagagtatca
     6421 gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa taaatggtga attatgtaag
     6481 attgatagag cttattctgg agaaattgtt attttgcaaa atgagttttt gaagttaaat
     6541 agtgttcttg gagatacaaa actattgcca cagagaaaaa agattgaaaa tccgcaccct
     6601 ctactacaaa caactgttga accgagtaaa cctgaacaga gagaaatgtt gcttgatgcc
     6661 cttttggaaa tctcagatag tgatccgctt ctacgatatt acgtggattc tacgacacat
     6721 gaaattatac tttctttctt agggaaagta caaatggaag tgattagtgc actgttgcaa
     6781 gaaaagtatc atgtggagat agaactaaaa gagcctacag tcatttatat ggagagaccg
     6841 ttaaaaaatg cagaatatac cattcacatc gaagtgccgc caaatccttt ctgggcttcc
     6901 attggtttat ctgtatcacc gcttccgttg ggaagtggaa tgcagtatga gagctcggtt
     6961 tctcttggat acttaaatca atcatttcaa aatgcagtta tggaagggat acgctatggt
     7021 tgtgaacaag gattgtatgg ttggaatgtg acggactgta aaatctgttt taagtatggc
     7081 ttatactata gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg
     7141 gaacaagtct taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt
     7201 tatgcgccac aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac
     7261 atcgtagaca ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg
     7321 tgtattcaag aatatcgtag tgatttaact ttctttacaa atggacgtag tgtttgttta
     7381 acagagttaa aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca
     7441 aatagtcgga tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt
     7501 tgttatataa atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa
     7561 ttaaagtgta aaggaggaga tagttattat aaactacaag tggatattgt gtcctgtatg
     7621 tggaaataaa acacgattaa agataaggga agatactgaa ttaaaaaaat tccccctcta
     7681 ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag cagttcaaag taactgtgat
     7741 tacagagcca gacgcaaaga cgcagagccg ataaaatgag attaatacaa tctcatttta
     7801 tcggctcttt ccgttatgta tggattcttt taattagtct tcgatgtttc ttgcttcgtt
     7861 gataccgctg gctaaagatt ccattaagga tagttctttg tctgtaaagc tatccatgta
     7921 tttctctatc tgtaatcgtc gggtgctttt taccaagtta ttagcaggta agaaaaattc
     7981 atcaacggaa acatgaagta acgatacaag gtcataaaga acttgtatgc tggggtgttg
     8041 ccctttattt tcaatattag ttaagtaccg tgggtcaatt tcaatcaatg ctcccacttg
     8101 ttcacgagtt aaacctcgtt tcaatcgagc ttctttaatg gctaaaccaa aggctctaaa
     8161 atcatattta tcttcttttt tacgcatagt agaccacctc tatacatttt attgttccta
     8221 ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt tataggttta tatttaataa
     8281 aaagcactac taaacgccaa taaaaaaaac cgttatatgg tagtgctatt tacgctgtta
     8341 aaatattgta tattacttcc aaatggcggt ttgttggagg tcaacgtcgc catgaagtac
     8401 atcatataca ataaatttcc ttacattggg ttcttgtcaa aaaaagtcgt ctatctgcaa
     8461 tagataagta cgtccaccaa tgtggtttta taaatcatat agatagaata acagaagcat
     8521 gtaaacagag aaataaatct gtttatatgc ttttttggct attcagaact tttttacaaa
     8581 gtttatttat cagtaatgca acaaatcccc ctttcacatt gggactaaga gtgaaaggag
     8641 ataaacgagc aaggctcact tcctttccta gacagaaagg gggtgagaaa catgaaacca
     8701 tcttcttttc agaccacaat agaaaatcag tttgactata tctgtaaacg tgctatggaa
     8761 gacgagcgaa agaattatat gctttatctt tcaaggattg caaagcgtga ggtgtccttt
     8821 tcggatgttg gcgattatct tgttagccag tttgcgacaa cagataacta ttcaactgac
     8881 tttcagattt ttacactcaa tgggttatca gtaggcgttg aaaatgattt gttgagtgaa
     8941 gcattacgtg agttgccaga caagaaacgt gaaattctac tgctgtttta ctttatggac
     9001 atgagcgatt cagaaattgc agacctgttg aaattgaacc gttctactgt ctatcggcat
     9061 agaaccagtg gactagcctt aattaaaaag tttatggagg aatttgaaga atgaaaacac
     9121 aatatcctat gattcccttt cctctcattg taaaggcaac agatggcgat accgaagcga
     9181 ttaaccagat tctacatcat tacagagggt acataacgaa gcgttcccta cgacttatga
     9241 aagatgaata tggcaatcaa agtatggtcg ttgatgaagt cttacgtgga agaatggaaa
     9301 ccagactgat tacaaagatt ttgtcatttg aaattaagta atatcctctc tcctttcgtg
     9361 gaagcgtgct aaaccattcc acgcttcccg aacagggagg tttgttattc caccaaagca
     9421 tattgagctt tcaatgtgtt ttgataggct aacgagccat tgttctttga aaactgaata
     9481 aaagtaatcg aatacgtttc gataagaaaa gagccaacgg aactaaccgc catgacctat
     9541 cttataaaga tagcgagcga ttcatgttag tgatccgaga agcaatcttt agcaggattg
     9601 cctgcaacga cattcttatc gtgataatga tactcccata cagtcaatag tccgagcgtg
     9661 ataaaaccgt cgcaggcaat gagtatggct acatgagaac catgcagggg tggaactccc
     9721 gtgagctttg ctaaagctgt tcgattgctg gtaaaacaac ttttatgaaa tccaaataag
     9781 tgatttggaa aggaggattt tatgaagcag actgacattc ctatttggga acgttatacc
     9841 ctaaccattg aagaagcgtc aaaatatttt cgtattggcg aaaacaagct acgacgcttg
     9901 gcagaggaaa ataaaaatgc aaattggctg attatgaatg gcaatcgtat tcagattaaa
     9961 cgaaaacaat ttgaaaaaat tatagataca ttggacgcaa tctagcgtcg ccaaagggtc
    10021 ttgtatatga taaaatagta ttaagtcgta tcaaggctct ttccataaag gaaaggagca
    10081 aatgccatgt cagaaaaaag acgtgacaat aaaggtcgaa tcttaaagac tggagagagc
    10141 caacgaaaag acggaagata cttatacaaa tatatagatt catttggaga accgcaattt
    10201 gtttactcgt ggaaacttgt ggctacagac cgagtaccag caggaaagcg tgattgtatc
    10261 tcacttagag agaaaatcgc agagttacag aaagacattc atgatggtat tgatgttgta
    10321 ggaaagaaaa tgacactctg ccagctttac gcaaaacaga acgctcaaag accaaaggtt
    10381 agaaaaaaca ctgaaactgg acgcaaatat cttatggata ttttgaagaa agacaagtta
    10441 ggtgtaagaa gtattgacag tattaagcca tcagacgcta aagaatgggc tattagaatg
    10501 agtgaaaatg gttatgctta tcaaaccatc aataactaca aacgttcttt aaaggcttca
    10561 ttctatattg ctatacaaga tgattgtgtt cggaagaatc catttgactt tcaactgaaa
    10621 gcagttcttg atgatgatac tgtccctaag accgtactaa cagaagaaca ggaagaaaaa
    10681 ctgttagcct ttgcaaaagc tgataaaacc tacagcaaaa attatgatga aattctgata
    10741 ctcttaaaaa caggtcttcg tatttcagag tttggtggtt tgacacttcc agatttagat
    10801 tttgagaatc gtcttgtcaa tatagaccat cagctattga gagatactga aattgggtac
    10861 tacattgaaa caccaaagac caaaagtggc gaacgtcaag ttcctatggt tgaagaagcc
    10921 tatcaagcat ttaagcgagt gttagcgaat cgaaagaatg ataagcgtgt tgagattgat
    10981 ggatatagtg atttcctctt tcttaataga aagaactatc caaaagtggc aagtgattac
    11041 aacggcatga tgaaaggtct tgttaagaaa tacaataagt ataacgagga taaattgcca
    11101 cacatcactc cacatagttt gcgacataca ttctgtacca actatgcaaa tgcaggaatg
    11161 aatccaaagg cattacagta cattatggga catgctaata tagccatgac gctgaactat
    11221 tacgcacatg caacattcga ttctgcaatg gcagaaatga aacgcttgaa taaagagaag
    11281 caacaggagc gtcttgttgc ttagtagtac aaatgaattt actacttatt taccacttct
    11341 gacagctaag acatgaggaa atatgcaaag aaacgtgaag tatcttccta cagtaaaaat
    11401 actcgaaagc acatagaata aggctttacg agcatttaag aaaatataaa aagataatta
    11461 gaaatttata ctttgttta
//
LOCUS       DBGJFK010000171         9242 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.113, whole genome shotgun sequence.
ACCESSION   DBGJFK010000171 DBGJFK010000000
VERSION     DBGJFK010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9242
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.113"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            344..976
                     /locus_tag="ACOIAP_003675"
     CDS             344..976
                     /locus_tag="ACOIAP_003675"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HGZ2640504.1"
                     /translation="MTIPNSTKVYPRNNDYQTVYLKNVITRENIEVGDYTIYNDFCND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHTLKSKSTYTFPIFYEEW
                     GLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVHIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNNTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDELV"
     gene            complement(1349..2218)
                     /locus_tag="ACOIAP_003676"
     CDS             complement(1349..2218)
                     /locus_tag="ACOIAP_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGZ2640505.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELIELRKLGVKMIYLGLESGSNEVLEDIKKGFNSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGKISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(2314..3171)
                     /locus_tag="ACOIAP_003677"
     CDS             complement(2314..3171)
                     /locus_tag="ACOIAP_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGZ2640506.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKKNNRKFN
                     IKNKIFKGIGILFVLILLSFFIWINKTYEPQKLAKEALISNSKVEVTVKENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVVASNFARDNKLIDGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNLS"
     gene            complement(3386..5404)
                     /locus_tag="ACOIAP_003678"
     CDS             complement(3386..5404)
                     /locus_tag="ACOIAP_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGZ2640507.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYIFSYDLK
                     RAVYVPFGLMYIFMVSIPVGISEFPMRLSALAAGAVIIMIAQFVMNRNRMKNIGDKEL
                     ISICDELLEKISLLKNIINDDSSISKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERINLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEVNYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKI
                     KSRDEKKAERKSNIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIDMYKGIVKNIIDEVNKSIENVADVYYIKNLLLVPSLIEDRIMLINAI
                     YKDKYQEDFLENQKLLISNMYNLYINVNKNKIQDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKTLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEVA"
     gene            complement(5676..6452)
                     /locus_tag="ACOIAP_003679"
     CDS             complement(5676..6452)
                     /locus_tag="ACOIAP_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGZ2640508.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALILGLIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     VLCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSIANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(6509..7480)
                     /gene="asrC"
                     /locus_tag="ACOIAP_003680"
     CDS             complement(6509..7480)
                     /gene="asrC"
                     /locus_tag="ACOIAP_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HGZ2640509.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLTIVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTKFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDGDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDENSIIKIILNTYKYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGVKYL"
     gene            complement(7493..8284)
                     /gene="asrB"
                     /locus_tag="ACOIAP_003681"
     CDS             complement(7493..8284)
                     /gene="asrB"
                     /locus_tag="ACOIAP_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HGZ2640510.1"
                     /translation="MNPYIPVNAKILDIVKHTDKEWTFRVNCDTKGVLPGKFYEISIP
                     KYGESPISVSGYGENYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIAGFKSPKDVLFADDLKRWSKKLDI
                     LVTVDGADEGYSGNIGLVTKYIPELDIKNINNTSIVVVGPPMMMKFTVGEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDNTYICLDGPVFDYSYAKNLID"
     gene            complement(8285..>9242)
                     /gene="asrA"
                     /locus_tag="ACOIAP_003682"
     CDS             complement(8285..>9242)
                     /gene="asrA"
                     /locus_tag="ACOIAP_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016002 - sulfite reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HGZ2640511.1"
                     /translation="KKDYKIFAPVSIPFKGTFSDTDVIRYKEVNSFEEMEFTKKANFS
                     PKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDINGIKRLDEIYLNNGEEKDY
                     FYKNIREKVKFVLVGCKESFRNCFCVSMDSNKTDNYSIGLNIEGDTLYLDIKDSEFEI
                     FNGETTEFNIDYVTDNLISVDVPENIDSNEMIRNSIWDEYDTRCIGCGRCNFVCPTCS
                     CFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRKKQGERMRFKTMHKIHDF
                     KKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVTSKEEI"
BASE COUNT         3073 a         1580 c          887 g         3702 t
ORIGIN      
        1 tttacagcta tacttcaaga gtaattgatt gtaatagtac catataatca tcctttagca
       61 ttaagtgaca gtgtagatta aaaggataac aatgttaatg ttctttaaat taaaaattat
      121 tttgtatata aaatatatta aattattgca agctttattg ttttgatata caatcaacta
      181 agcatatagc ctttataaaa tactaaatag ttaaaagtct gtttttaaaa acaaaatgta
      241 taaattaaaa tatagatact atcaaggagt gattctgtga agagatgtat tgtaatagtg
      301 gaatagtcaa aaacataata tatatcaaag gagagattta aatatgacta ttccaaattc
      361 aactaaggta tatccaagaa ataatgatta tcaaactgta tatcttaaaa atgtaataac
      421 aagagaaaat atagaagttg gagattacac aatatataat gacttttgta atgacccaag
      481 agattttgag aaaaacaacg tattatatca ttaccctatt aacaatgata aattaataat
      541 tggtaagttt tgctcaatag catgcaatgc aaaatttcta atgactagtg gaaatcacac
      601 actgaaatca aaatccacat atacctttcc tatcttttat gaagaatggg gactcgatat
      661 caatcatata acggatgctt gggacaataa aggtaatatt ataattggaa atgatgtgtg
      721 gataggctat gattctataa ttatgtcagg tgtacatatt ggcgatggtg caattattgg
      781 aacaagagca gttgttacta atgatgtccc accatattct attgttggag gagtacctgc
      841 aaagattata aaaaaaagat ttaataataa tacaatttca aaattattgg aaattaaatg
      901 gtgggattgg ccatataaaa aaatccaatc aaacattaag catattcaat caggaaatat
      961 agatgaatta gtttaatctt ttataattta tatatattaa attttacttt aataatcctt
     1021 tttataagaa ttttttcaag atttgtatat cattttaata tatataaatt taatacaata
     1081 ctaaacaaaa ataaaaagta aagttgctta atataaagtt actttacttt ttattattta
     1141 aattcatggg tccattataa tatgtaaaat tctattaaac cagttcacat tttcatcatt
     1201 attgatagcc tatatatgaa cataccattt tgttttttaa caaaaaaatc atgctatatt
     1261 aatagtaaaa aactattaat atagcatgat tttttgtatc taaacaatct cagtatttat
     1321 ctataaatat agattgatat atcaaaaact acagtcttct atattcttct ctttttaact
     1381 tttggttact tagatagtaa tcaatttcat caattagacg ttgtttgtca tcaggtaata
     1441 caccttttaa attagcataa tttgatgcat gattacttct aaatacaatt ttttcattgg
     1501 catctatatt ctttatcatc tctttaattt cttgtaacac agccttatcc tctagtattg
     1561 taaactctcc tgccttaagt aaatcgtaaa gttcagtatt aggttctacc attaaactaa
     1621 gtacacctac ataatctggt gaaatttttc ctaacatttt tcctgtatca acggcatgct
     1681 gatgtgtttt tttagttcct ccaagacctg ctattacagt ggctgataat ttaatcccac
     1741 tttttttaac ttttctacca acttttatta attgttcact attaaaacct ttcttaatat
     1801 cttccaatac ttcattgctt ccactttcaa gccctaaata aatcatttta acaccaagtt
     1861 ttcttaactc tataagctca tcatcagatt ttttctctat agatttagga gaaccataca
     1921 tagtaattct ttcacactct ggaaaaactt cttttatata taaaattatg tctcttaatt
     1981 tctccattgg tattatcaat gcatctccat ctgctaagaa tattctttct acatgtttat
     2041 aatatcttct aaatatatca atttcatttt ttattacttc tagtggcttt attttaaatt
     2101 ttttagattt gtacatacta caaaacgtac atttgttgtg agaacatcct agtgtgactt
     2161 gtattataag actataagcc tcacttggcg gtctgtaaag tggcatatcg tattccatat
     2221 taaaatcccc cttgtaataa aatatttatt ctattatatt attaatattt actttaaata
     2281 ataacttata aaattatatt ttttaatttt agtttaagat aaattcttta aaaatttaat
     2341 gatactattg gcagtaatat taagttgttt ttcttgactt ataatagcat cattatctcc
     2401 cttttgtttt ccatagtctc caaattgtgc atgatttcct ccttcaattt caacataagt
     2461 tgtatcatca ggaagttttt gttttgattc tacaagactt ttaaaattga ctacaccatc
     2521 tttgctcccc catatagata taactttttt tcctaattct ttcaactcat ctcccattgg
     2581 ataagaagct aaaaatacaa ctccatcaat taatttatta tcacgtgcaa aatttgatgc
     2641 tacaactcct cctaatgaat gacctcctat tacccaatgt tctatgttgt tgtaagaatc
     2701 cataactttc tgcgccttat tagttccaag tatagctaga ttaagtggca tctttacaat
     2761 tacaacctca tatccacttt ctgctatttt tcttgcaagt ggtgcataag attctatttc
     2821 tactttagct cctggataca aaattaaacc tttagaaact tttcttcctt ttggtgtaaa
     2881 tgaaatgttt tcttttacag ttacttcaac tttactattg ctgattagag cttcttttgc
     2941 cagtttttga ggttcatatg ttttatttat ccatatgaaa aaactaagca aaatcaatac
     3001 aaatagtata cctattccct taaatatctt attctttatg ttaaattttc tattattctt
     3061 tttatcatct ttgttttcaa cctcatcata aagtaaaggt ctttcgagtt ccatagttat
     3121 actaaatgta tcatatttct tattgcgttt tacctttaca tctttactca taaatctaac
     3181 ccccataata tttgaatact attatagttt atcctaagta aattgttttt tcaaccaatg
     3241 aaaaaaatca atattttaac tattttcata taaaattcat aaatatatgt tttttgtttt
     3301 ttatatatta ttttctttta atattttata aaacaaatag ccatatactt tattttaaat
     3361 atatggctat tctataattt aatatctaag ctacttcttt tattgaaact ttagttatat
     3421 tacttattct atacatttct ttgacaccat ttagagtttg cagtaagttt agacatatta
     3481 tcttgtctcc tagagtttta gtatttacaa tactctctaa aattacgctt cttccctcat
     3541 catacttatc tacattgtaa tttgaaatat aattagtatc tctcaatatt ttttcaacat
     3601 cttcatcttg tattttattt ttattaacat ttatatatag attatacata ttacttatta
     3661 gtaatttctg attttctaaa aaatcttctt gatatttatc tttatatata gcatttatca
     3721 acataattct atcttcaata agtgatggta ccaataataa attctttata tagtaaacat
     3781 cagctacatt ttctatagac ttattgactt catcaattat atttttaacg attcctttat
     3841 acatgtctat cacatgttga tagcctgttt tagcatcata tggtaatata aacttattta
     3901 ctattaatgc aataattgct cctaatgcta catatgaaat cctgcttatt gttaaaacat
     3961 ttgggtctcc cataactaca gctgaaccaa gagctgaaac agttacacat accattaatt
     4021 ttctataatc aactacataa gagtttatat atcctgctaa aagaactatt aacgacctta
     4081 atgtactatc ttttattatt gaaaataata caataaatat tacagctcct ataaatgtac
     4141 cttctattct ttttctagac ctttgtatac aattttctgc gtaaggttgt gttaatgaaa
     4201 aaacagttaa cattatccat cttccatccc ttaaatggaa ataatccata ataaaacccg
     4261 ctacagctgt agctaaagca atctttactg cataagaaaa tcttatagaa tttaaattaa
     4321 agtttttctt atatattgat agtcgtttaa attcatgagg tatatttgat tttctttcag
     4381 ctttcttttc gtctcttgat tttatttttt tataatctac taaaaactca tataaatttt
     4441 ctaaaacact ataaatttct tttaaattta tatttttagt atcctgagca ataacataat
     4501 ctctaaatcc taatatctct ttatcagtta tggtatcttt attttctaaa cacatcttaa
     4561 tatagtttac ttcttttgtt gctacaacta gaacatctga tttactattt atgctacttt
     4621 cttctaaaat attttttata tcttcatctt caaattcttt actatccttt ttgtatcttt
     4681 ctaggattaa atttattctt tctaatgaaa ataaaatatt cattatgtct atacctctaa
     4741 tacttatata aaagtcatct tttctattat caaaaataac cattttcaaa tttttagata
     4801 tagaatttat tctataatta cagctatcta tttttctcat actagattta cttatagaac
     4861 tatcatcatt aataatattt tttaaaagac taattttttc taataattca tcacatatag
     4921 atatcagttc tttatctcca atatttttca tcctatttct gttcataaca aattgagcaa
     4981 tcattattat aactgctcca gcagctaaag ccgacaatct cataggaaat tcacttattc
     5041 ctacaggtat acttaccata aatatataca ttaggccaaa aggtacatat actgctcttt
     5101 ttaagtcata actaaatata taccctatta taaataatgc tataaaattt aataaaacgc
     5161 ctaaatacat attttgtact gcaaaaaatg atagtattcc taggattata tttattgcta
     5221 aatactttag taaattttta attggagaaa tagttaaatc tctttccaat agtgttagca
     5281 tagctgttac tataccaaca cctataagtg tgtttttact tccaaataaa tatatgaata
     5341 tagaaataaa tgctattata aaaataaaca attttgtttt tgatattact agtttctttg
     5401 tcattatatc ccccctaaaa atttcaacaa gaccaatttt atcatatttg ttatcttatt
     5461 caaaatactc ttttttacgg taggacttta acttttttta cattttgaac tatataatct
     5521 atatttaaac gtattttatt gcatatatag tttatatatt ttcgtatgct cccatatatt
     5581 ttttctttca aatatttttt caaaaatata aaaataactc tctcaacaat actaaaactg
     5641 tatttattaa gagagttata atttatacaa taaatttaat taagcttttc tttacccaat
     5701 atataagttc caagacccat aaataaagct cctccaacaa tatttccaag tgtcacagct
     5761 actaaattat aaatagctcc tccaatagta actgtactta ttgttggtga aaataatgaa
     5821 acactataaa ttgtcatatt tgctatacta tgctcaaaac ctgatgttat aaaggcaaat
     5881 aaacataaga atatcataat tatttttgca gtatcactat tagttctaaa cgaacacaat
     5941 actgatacac ataccagaat attacataaa acccctctaa agaaaagagc tgtaaatggc
     6001 atggatgctt tactagctgc tgtatttgca aaaaattcag ctacaggtcc tttatctact
     6061 agaccagttc ctacaaatat aagacctaaa attaaagctc caattaaatt acctacccaa
     6121 ctgtatgccc atattttaga agtatctttt atacttacac ctttatttaa cataccagca
     6181 gacataacca tattgtttcc agtaaataac tctgttcctg tcattataac taaacttagt
     6241 gctattgcaa aggataaccc cattactatc ttagtcatag gtgaacctgc atcagtcaaa
     6301 agtcctccaa tagtaaatat caaaagtata cctattccta cataaagtcc tgcaaacgca
     6361 gaagatacca aatattttac tttacttgtg tttaataaat ttatcttatt tatagctgca
     6421 ttagttaatt tatccaaagt ttctttatgc ataattccct cttccttcta ttaaatttta
     6481 atttattcaa atatatgttt tactcaattt atagatattt aactccactc cagtatatgt
     6541 tttcatacat tttagttatt tctggaagtt ctacaccttc aagcgcccat tttttaaact
     6601 ccataaatcc tgttctatca attatatatc ctatatgttc ttttcctcct ggtgcatctt
     6661 tatctatata cttttctaca tatttgtaag tattaagtat tatctttatt atgctattct
     6721 catctaccca taaaagaaaa tcttctgcta gtctagggtt tttctttcct gttctaccca
     6781 ttatagctaa tctatagtat tttttctcat ctctagtcca tgcatttgtt gggcaattta
     6841 gtacacattc tccacatcct atacatttat ctccatctct taccacctta ttattttctg
     6901 tttttaatgc tccaacagat attttagaac atttttttac acacgctcca caatttacac
     6961 atctatcttt ttcatatatg ggtaaagcca taccaataat tccaaaatca ttcattctag
     7021 cttttataca atcatttgga cagccagtta aagccacttt aaaatgtaaa tcatttggaa
     7081 atatagcttt ttctattctt ttagcaaatt tagttgtatt atattgagcc tttggacaga
     7141 ctttatttcc tatacatgct gctatatttc ttgtacccgc tgctggataa cctgcatttt
     7201 tctcactttg atttatattc attttttcaa taacaggttg tataatttta tttatttctt
     7261 ccatatcttc catatttatt cctaatattt caaagccctg tcttgtagtt atgtgtacct
     7321 gtccattacc atactcactt gcaattttag aaactatagt taaactctca gggtcaataa
     7381 gcccaccagg tactctaacc cttaaagaag tctcatattt tgtttttgta atcctataag
     7441 catttttcat tacttttttg gtatttaaat ctcttatcac aaacttcgcc ccctaatcaa
     7501 taagattttt agcatatgaa taatcaaata ctggtccatc taaacatata taagtgttat
     7561 ccattttaca gtgtccacat ttacctatac cacaacacat ttttctttca taagaaaccc
     7621 aaatattctt ttcatctaaa tctcttttta aaaattctcc tactgtaaac ttcatcatca
     7681 ttggaggtcc aactacaact atagaagtat tatttatatt ttttatatcc aattctggta
     7741 tgtattttgt cactaatcct atatttccac tatatccttc gtctgctcca tctacagtaa
     7801 ctaaaatatc aagtttttta ctccatctct tcaaatcatc tgcaaataaa acatcttttg
     7861 gtgatttaaa tcctgctatt aatttaaact tttcgcattt ttctttattg ttgtaaaaat
     7921 attcaactat tcctcttaca ggggctaatg cacttcctcc tgccactact acaatttctc
     7981 ttccttcgta aagagataca tcaaatccat ttccataagg ccctcttata aaaaaagaat
     8041 ctccttcttt ataattaaac aactcactag ttacttttcc tacatttctt attgtaaagt
     8101 caatatagtt ctctccatat cctgatactg atattgggct ttcaccgtat ttaggtatag
     8161 atatctcata aaattttcca ggcaatacac cttttgtatc gcaatttact ctaaaagtcc
     8221 attctttatc agtatgctta actatatcta atatttttgc gtttactggt atatatgggt
     8281 tcatttatat ttcctcctta ctagttacta aatcatttat tttttctata cattttgaaa
     8341 atgatatgta ttgtggacag gcatcatcac atcttccaca accaacacac atatgatatc
     8401 cgaatctttt tttaaaatca tgtattttat gcatagtttt aaatctcatt ctttcacctt
     8461 gtttttttct aaaagaattt ccacctgcta tatctgtata tccatctact tgacaagaag
     8521 cccaaactct tcttctctca cctacattct cattttcctt atagaaaata tcctgcattg
     8581 taaaacatga acatgttgga catacaaaat tacatctacc acatcctata catcttgtat
     8641 catattcatc ccatatagaa tttcttatca tttcatttga atcaatattt tctggcacat
     8701 ctacagatat taaattatca gttacataat caatattaaa ttcagtcgtt tctccattaa
     8761 atatttcaaa ttcactatcc tttatgtcta aatacagtgt atctccttct atatttaatc
     8821 caattgaata attatcagtt ttgttagaat ccatactcac acaaaaacag tttctaaaac
     8881 tttccttaca ccctacaagt acaaacttta ctttctctct gatattttta taaaaataat
     8941 ctttttcttc gccattattt agatatattt catcaagtct ttttatccca tttatgtcac
     9001 aagctctcaa gaaaattaaa attttcttgt tgtctaaatc gctttcctta aactcttttt
     9061 cagtaaaata aaataatact tgatttatag gaagtacaac ttcttttggt gagaaatttg
     9121 ctttcttggt aaattccatt tcttcaaaag agtttacctc cttgtatctt ataacatcag
     9181 tatctgaaaa agtaccttta aatggtattg aaactggtgc aaatatcttg tagtcttttt
     9241 tt
//
LOCUS       DBGJFK010000172         8295 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.120, whole genome shotgun sequence.
ACCESSION   DBGJFK010000172 DBGJFK010000000
VERSION     DBGJFK010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8295
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.120"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            275..967
                     /locus_tag="ACOIAP_003683"
     CDS             275..967
                     /locus_tag="ACOIAP_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640512.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEHIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKNDNYSKVHGLRAGADDYLTKP
                     FEIAEFTARVLSLIRRYTRFNPKNEESQQLSFKGLLIDLDQHTVTTNGETMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            964..1899
                     /locus_tag="ACOIAP_003684"
     CDS             964..1899
                     /locus_tag="ACOIAP_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGZ2640513.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYIEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLDFEIDIPENRLMVNLDSDGYSRVVNNLVQN
                     VLAHSKARRIKITMSEDSKMVLLRVEDNGVGIAKENLQHIFERLYKCDKGRSKKGSGL
                     GLSIVSQMVERMGGKISVESEIGKYTVFIVSLPLI"
     gene            2049..2972
                     /locus_tag="ACOIAP_003685"
     CDS             2049..2972
                     /locus_tag="ACOIAP_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGZ2640514.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGSGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRNLCTERGKTILISSHILSEIALLADDIGIIDRGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLEIQLNLKNFKVADNHNIMLYDTDVSVAEINRAF
                     IQNNIDVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            2956..3726
                     /locus_tag="ACOIAP_003686"
     CDS             2956..3726
                     /locus_tag="ACOIAP_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640515.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIVFGIMFFVTALPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICIIYKKQEN"
     gene            3736..4518
                     /locus_tag="ACOIAP_003687"
     CDS             3736..4518
                     /locus_tag="ACOIAP_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGZ2640516.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQIVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFVITLIGGYLINREYTDQTLKNILTIPISLRKLLVGKL
                     IAVGGITVLLSIFSFLCTFILGLLFCNINISVILVAKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNSFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLAGYNNDDGSVYQPLI
                     GVMTLVVILILTAILLTFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            4896..5432
                     /gene="rbr"
                     /locus_tag="ACOIAP_003688"
     CDS             4896..5432
                     /gene="rbr"
                     /locus_tag="ACOIAP_003688"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HGZ2640517.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            5464..5853
                     /locus_tag="ACOIAP_003689"
     CDS             5464..5853
                     /locus_tag="ACOIAP_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HGZ2640518.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLSQLTEHGFIKKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLKELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            5890..6276
                     /locus_tag="ACOIAP_003690"
     CDS             5890..6276
                     /locus_tag="ACOIAP_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin family protein"
                     /protein_id="HGZ2640519.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNSVTVKVSSAIHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            6403..7845
                     /locus_tag="ACOIAP_003691"
     CDS             6403..7845
                     /locus_tag="ACOIAP_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HGZ2640520.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDENIAEDIVEDEPKLNTEKDGDLNYVSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAKSKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGKDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            8142..8264
                     /locus_tag="ACOIAP_003692"
     CDS             8142..8264
                     /locus_tag="ACOIAP_003692"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGZ2640521.1"
                     /translation="MEKLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFD"
BASE COUNT         2920 a         1088 c         1591 g         2696 t
ORIGIN      
        1 ccgtatatag taaatgtatt atcatgtttg ttttatttaa gcacacttat aatatgcttg
       61 attttttcaa aatgatgaaa tatactaatg ggtgttggat gtataagaat cacattatac
      121 ttgaaaaagt aagtgagaaa tgaggtataa ttcctcatat gataaactac tattgtattg
      181 tggaacatat tctcagtgat gtcaagatat tacaatatga ctaaattcct aatgataaaa
      241 aagtctacga atgagtgtag aaaggggaac taagatgaat aaagttttaa ttatagatga
      301 tgataaagat ctttgtattt tgttaaaaaa gagtatctca attgaacata ttgaagcaaa
      361 ctattgccat tctgggagag atggattggt tgaactttca aaacaagatt atcagttagt
      421 agttctagac gtgatgatgc caggtatgga tggttttgaa actatggaac aaatacgaaa
      481 atatagcagt attcccatct taatgctgac atcgaaaaat gataattaca gcaaagttca
      541 tggattgcga gctggtgcgg atgactatct aaccaaacca tttgaaattg cagaatttac
      601 tgctcgtgta ctgtctttaa tccgacgtta cacccgtttt aatccaaaga atgaggagtc
      661 acagcaactt tctttcaaag gtctgttgat tgaccttgac cagcatacag tgactaccaa
      721 tggcgaaact atgttgcttc cacccaagga atttggtgtg cttctttact gtgcaaggca
      781 tcagggtaag attttgacaa aacagcagat ttatgaagct gtgtggggtg agccatatgt
      841 atatgatgac agcaatatca tggctattat cagtcgccta agaaaaaaaa ttgaactaga
      901 cccatcatct cccatctatt tgcaaacgat aaaaggaatc gggtatcaat tcaacacgga
      961 ggtatgaaaa tggatgaaca aacgataatt ctttttttgt ttttgctgtc gattggtcta
     1021 cttttccttt ccatatttgc tttttccaag cttggtcata ttcacaaacg tctaaaagat
     1081 atagaagaaa tacttgctga tgtacaaatt ggaaacgaaa atcgaaaaat actaattaag
     1141 ccatgtgatg ttatggctcc attggtttat cagcttaatg agattgtcta cgattatgaa
     1201 aataagttac tttctctgaa aaagtcggat aaagctagca aacaacttat gacaagttta
     1261 tctcatgatg ttcgtacacc attaacgact ctgattggtt atctggatgc tgtacacagt
     1321 ggtatagtta tcggacaaga acgggaggaa tacattgaaa tcgctcggcg tagagcctac
     1381 gaccttaagg attatatcga tgttcttttt gactggtttc gattgaactc tgatgaattt
     1441 acgttgtcaa tagaatctgt ggaaattgca gagttgtcac gtaatattct taaagattgg
     1501 attcctatct tccatgaaaa gaaattggat tttgaaattg atattccaga aaatcgacta
     1561 atggtaaacc ttgattcaga tggatattct cgtgtagtca ataatctagt tcaaaacgtt
     1621 cttgcccata gcaaggctcg ccgaatcaaa attaccatga gtgaggattc taagatggta
     1681 ttacttcgtg ttgaggataa tggtgttggg attgccaaag aaaatttaca gcatattttt
     1741 gagcgactgt acaagtgtga taaaggacgt tcaaaaaaag gaagtggtct tggtttatcc
     1801 attgtcagtc agatggtgga gcgaatgggc ggtaagattt ctgtagaaag tgaaattgga
     1861 aagtataccg tatttatagt gagcttacca ttaatataaa aattgttttt cccccatgtg
     1921 atatatatac acagggggga ttttttataa gctataaagt tgcaaggtta atacaaggtt
     1981 gttgcaaggt taatgtaaga ttgaggtggt atgataaatt taataaacaa aggaggattt
     2041 tactatttat gaataattta attattgaaa caaaaaatct cactaaacaa tatggtgctc
     2101 aaaagagcgt ttctaatttg aatattcatg ttcagaaagg tcgtatttat ggattgctgg
     2161 gaagaaatgg ttcgggtaag acgacaacta tgaaaatgtt attgggtcta acaaaaccaa
     2221 ctactggaga aattaaaata tttggtcagg atattcataa taacgagaaa aagcttcttc
     2281 ctagaattgg atgtttgatt gaatcaccag gtttttatcc taatctgaca ggaacagaaa
     2341 atctcaaaat ctttgcgagg cttagaggaa taccaaaaaa aaatgcagta gaatcagcac
     2401 tggatgtagt cggtttgcca aacaatgaca aaaagttatt ttctcaatac tctcttggta
     2461 tgaaacagag gttggcaatt gctcttgcca ttatgcatga cccacaattg ttgattttgg
     2521 acgagcctat caatggactt gatcctattg gtattgcaga agtaagaaag tttattcgta
     2581 atctctgcac agaacgaggt aaaactattt tgatttccag tcacattctt tctgaaattg
     2641 ctttgttggc agatgacatt ggcattattg accgtggcat tttgttggag gaagaaagcc
     2701 ttgcacaact ggaagaaaaa aacagtaaat acatacattt tgctgtatct gatgcagcac
     2761 aagcagcaag acttctggaa atccagctta acctgaaaaa tttcaaagtg gcagacaatc
     2821 acaatattat gctttatgat acagatgtct ctgttgcaga aataaatcgt gctttcattc
     2881 aaaacaatat tgatgtatca gaatctcatt tgtgcgaaga tactcttgaa gattacttca
     2941 agaaagtaac agggggtgaa ggaattgctt gatataattt catgcgaatt ttcaaaactc
     3001 aagcggttaa aatttatact gatttctatt ttaggtgctt gtttatttcc aattcccgca
     3061 acaattttga ttgcaaagga caacttgcct tttgagcaat tgttcaaatt agttgtcaat
     3121 tttggatatt ttttgctatt accaattgta ttgagtattg ttgctagcca actctttttc
     3181 atagaaagag ataacgatgt attaaaaaat ctagcaacag tgccagtgcc aaaaggaaaa
     3241 ctggctctgg caaaattagc tgtgttgctg tttatatcat tgttctactc cgttgcaggg
     3301 ttaggagcta ctatcatagg aggtttcatt gttggaatag tagagggggt tgctgtaaaa
     3361 ttaggaatga gtattgtttt tggaattatg ttttttgtta ctgcacttcc tgttgtggta
     3421 ctcattgtat atttcaatcg cagctatatt ttttctatta tactttcttt tgtatatgct
     3481 attttcaatt ttagtatatc cttaaatatt atcaactttg aaccaaataa cccactgtta
     3541 agcgtattac ctgctcctgt tataatgcgt tggtggatgg cattttgggg agatcccact
     3601 ggcgaataca cggcacttag acagccatat ttactctcaa ctcctgcttg tgtaggtatt
     3661 ttatgtttga taacaattat tgcagtcctg ttgatttgta taatctacaa gaagcaggag
     3721 aattaggagg tatctatgct tgatataatt actacagaat ttcaaaaaat aaaaagatat
     3781 aatattctat ggattggtgt tgttgctgtt ctgttttcag cactattggc ggtttttcag
     3841 attgtaagtt cacacggcag tgaccctcta acgtatgaga gctttgcaaa tggagttata
     3901 tggaataatt tcagtcttag ttttccattt gtgattacgc tcattggagg atatcttatt
     3961 aaccgtgaat atacagacca aaccttaaaa aacatcctaa ctattcctat ttcattacgc
     4021 aaattgctag tgggaaaatt aattgcggtt ggaggaatta ctgtattgtt aagtattttc
     4081 agcttcttat gcacatttat tttagggtta ctattttgca atatcaatat atctgttata
     4141 ctcgttgcaa aatccttagt tcagattttg tctgttaatc tgtattgtta tgttgctgtt
     4201 ttgccgatta ttgcttattt tggtcgtaaa caaaattcct ttttgacagg cgtagggatt
     4261 gcatttgtat atggcttctg tggtgtattt gttgctggaa gaaatctaac agacttttat
     4321 ccaatcacag caggtcttgg tctagctgga tacaacaatg atgatggtag tgtttatcag
     4381 ccacttatag gtgttatgac tttggttgta attctaatcc tgacagctat tctacttaca
     4441 tttacaccta attacgataa agttatgacc atatctaaga aaaaagggat aaagcataaa
     4501 aagtattctc ataaataaca taaatattgt ttctattatt taagttgtca ggcagtgaaa
     4561 agaaaaaatc tgtcgtacag tggctatatg ctcatgtatt taagaagcta cagttttgat
     4621 ttttcatagg tgtggcttct ttttgtattt attaaatcaa caactatcat aatatttgca
     4681 ataggtatag taacaagaga taatactgtc atatgtgttt tatatattac attaagtata
     4741 ttctaaaata tatgttttaa ataatatatt tgaaaataag aatacttgaa taaaaaaaat
     4801 aatattatat atagttgaca aaaagtggaa attaatatac tatataaata tagaaatagt
     4861 aatcattact aatattaaaa aaggaggaat taattatgaa cttaaaagga actaaaacag
     4921 aaaagaattt aatggcagga tttgcaggag agtcagaagc aagaaataaa tatacatact
     4981 acgcttcaaa agctagaaaa gaaggttata atcaaatagc tgctatattt gaagaaactg
     5041 ctaacaatga aaaggaacat gctaaattat ggtttaaact tttacatgat ggtatgcctt
     5101 caacagagga aaatttaaag gatgcagcag caggcgaaaa ctatgagtgg actgacatgt
     5161 atgcgaaatt tgctaaagaa gctagagaag aaggatttga caagatagct tatttatttg
     5221 aggctgttgg aaaaatagag aaagagcatg aagaaagata cttaaagctt ttagaaaact
     5281 taaatgaagg aaaaatattt aaaagagatg aagaagttgt ttggcaatgt caaaactgtg
     5341 gtcatgtgta tgtaggtact gaagcaccag aaaaatgtcc agtatgtgac catccaaaag
     5401 catatttcaa tataaaagct gaaaattatt aaaaattatc attattaaaa aggaatgtta
     5461 actatgaaat tttctaaaca acgagaactg attttgaatg aaatattaaa taatccggtt
     5521 catcctactg cggattacct atatgaaaac ttaaaaaaag ataatccaaa tctaagctta
     5581 ggaactgtgt atagaaattt atctcaacta acggaacatg gctttataaa aaaggttagt
     5641 attccagggt atccagatag atttgatggt agaatagata atcactatca tatcatatgt
     5701 gaagtatgtg gagaggtata cgatttagaa tctgaagttc ttaataattt aaaagaatta
     5761 atatctgagg agacagacat aaaaataaca tcttataaca taagttttaa agggatttgt
     5821 aataattgta aaagatgtag ccaagtaggt tagcttttaa attctaaaaa taattaatga
     5881 ggtgagttta tgtgtagcga acaaaaattt tttatatgtg agacttgtgg aaatcttgta
     5941 ggaatgatac aaagtggtgg tgtacctatt ttctgttgtg gaaaacctat gaaggagctt
     6001 gttcctaata caacagatgc agcagttgaa aaacatgtac ctgtgattga agtggatgga
     6061 aatagtgtta ctgttaaagt aagtagtgca attcatccaa tgactaaaga acatcatata
     6121 gcatgggtgt atcttatgac tgaacaaggt ggtcaacgca aatgtctagc agtagatgga
     6181 gaacctgtag ttaaatttgc tctgaatgat gatgataaag tgatttctgc atatgcttat
     6241 tgtaatttac atggtttatg gaaggctgaa ctgtaatatt taaataaatt gagtcaaaaa
     6301 ggaggctata aatgtatttt catacaaata gcctcctata aatttatata aattcgagtt
     6361 ttaattttat ttaatgtcaa tataatataa ggagaaaata atatgtcaat ttacaaatgt
     6421 agcgtttgcg gatatattta tgatgaatct aagaatgata aaacatggga tgaattaagt
     6481 gaagactggg aatgccctgt atgtacaaaa ggtcgtagtt attttggaaa gataagtact
     6541 gtttactatg aagaagatga aaatatagca gaagacatag ttgaagatga acctaaatta
     6601 aatactgaaa aagatggaga tttaaattac gtaagtacat atttaagaag agatgatgaa
     6661 gttgagaaac atatggatat aattcacgaa atggctgtta caggaaaatc tataatagaa
     6721 ccgatgagaa ctaaactacc agtaatttct tgggatgata ttttaattat gggtgctcaa
     6781 ttaaatccat tacctttaaa cgaacatgat gaagtaaata caacaacaat aatagggaaa
     6841 aaagcaaaga agcctatgat tatagaaaat ccagtttata tttcccacat gtcatttgga
     6901 gctttatcta aagaactaaa aatagcttta gcaaagggtg ccgctaaaag taagacagct
     6961 atgtgtagtg gagaaggtgg tatattacca gaagaaaaag aagcttcata taagtatatt
     7021 tttgaatatg taccaaataa atatagtgta actgaagaaa atcttaaaaa ttctgatgct
     7081 atagaaataa aaattggtca aggaacaaaa cctggtatgg gaggtcatct tcctggtgaa
     7141 aaagtaactg aagaaatagc aaaggtaaga aataagcctg taggtaaaga tgtaataagt
     7201 ccatcttgtt ttgaggaaat acaatccaaa gaagatttaa agaaacttgt agatgaactt
     7261 agagaagttt cagaaggtcg tccaataggt gttaaaattt cagctggtca tattgaaaaa
     7321 gatatggaat ttatagctta tgctaaacct gattttgtga ctattgatgg tcgtggtgga
     7381 gctactggag caagcccaaa gttgcttaaa gatgcaactt caatcccaac aatatttgca
     7441 ctttatcgtg ctagaaaata catagataca catggattag atatagattt ggttataaca
     7501 ggtgggcttc gtatatctac tgattttgcc aaggcaattg ctatgggtgc tgatgcagtt
     7561 gctattgcaa gttctgctct tatggcagca gcatgtcaac aatatcgtat atgtggttct
     7621 ggtaagtgcc ctgtaggagt agctactcag gatgaggaat tgagaaaaag attacatata
     7681 gaaaatagtg ctaatagagt ggcaaacttt ttaaatgtaa gtttagaaga acttaagact
     7741 tttgctagaa tttctggtca taaagatata catgatttaa gtgttgatga tttatatact
     7801 gttaactctg aaatatcaaa ttacacaaac atacaacatg tataagttga agtttgagac
     7861 tattagattg tagatagtta taaaagtaaa tgataaatat attttataaa aaggagtgtc
     7921 ttaaaatgaa ctttttagtt tataagtcac tcttttttgt atgaagccaa atatatttat
     7981 cattttaaca atgaaaaaga atcttatatc tttactttga gatagattcc ttctatttat
     8041 gaaaattaaa gatattaaat tgtaaaacat tctgtgatgt cgtactatta aactaaagat
     8101 gctgtacttt aaagtaaata aaaatttaag gagtgattat tatggaaaaa ttgaagattc
     8161 aagttctagt tgacaataat acatatattg ataggtactt tgttggagaa ccagcagtaa
     8221 gctattacat tgagattgat ggaaatagga ttttgtttga ttaaaaaata gctacgaaca
     8281 cttgtgactt tagtc
//
LOCUS       DBGJFK010000173         6278 bp    DNA     linear   BCT 20-MAR-2025
DEFINITION  TPA_asm: Clostridioides difficile isolate B32
            SAMN43225839-rid25700753.guided.128, whole genome shotgun sequence.
ACCESSION   DBGJFK010000173 DBGJFK010000000
VERSION     DBGJFK010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43225839
            Sequence Read Archive: SRR30483180
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002674342.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002674342.1
            Genome Coverage       :: 131x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/17/2025 19:39:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,700
            CDSs (total)                      :: 3,638
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 62
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 8 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6278
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43225839-rid25700753.guided.128"
                     /isolate="B32"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Denmark"
                     /collection_date="2020-01"
                     /collected_by="SSI"
     gene            261..998
                     /locus_tag="ACOIAP_003693"
     CDS             261..998
                     /locus_tag="ACOIAP_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGZ2640522.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTRLNEENFSIKLFKADVSNREDVENMVDYCIKEFGGLDVLVNNAGISQDKLFTDITD
                     VDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDILVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            1096..1980
                     /gene="rsgA"
                     /locus_tag="ACOIAP_003694"
     CDS             1096..1980
                     /gene="rsgA"
                     /locus_tag="ACOIAP_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGZ2640523.1"
                     /translation="MLEGKIIKGISGFYYVDTHNGIYECKARGIFRKHKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKKIYELSGYKVIPVSNITKLNIEKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVANGEISKERY
                     ESYIQLLNEIRQNNSRRY"
     gene            1985..2656
                     /gene="rpe"
                     /locus_tag="ACOIAP_003695"
     CDS             1985..2656
                     /gene="rpe"
                     /locus_tag="ACOIAP_003695"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGZ2640524.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPIDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVDKVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            2665..3306
                     /locus_tag="ACOIAP_003696"
     CDS             2665..3306
                     /locus_tag="ACOIAP_003696"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGZ2640525.1"
                     /translation="MKICIVLNGEIEDYEVTRGIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     KGDAKGVTLTGLEYPLDNYYMRYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            3437..4066
                     /locus_tag="ACOIAP_003697"
     CDS             3437..4066
                     /locus_tag="ACOIAP_003697"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGZ2640526.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIDLSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERNNLLNECSLKECEYLSENGAKLFDDIENTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFVDFECPGNTGLHKGENNKLIIERNKLKNPI
                     YIGDTQGDANSAKFAGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            4121..4777
                     /locus_tag="ACOIAP_003698"
     CDS             4121..4777
                     /locus_tag="ACOIAP_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGZ2640527.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVIIKRRDLMEKIADVITKKQQEILVEMEKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            5172..5894
                     /locus_tag="ACOIAP_003699"
     CDS             5172..5894
                     /locus_tag="ACOIAP_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGZ2640528.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIIDIMMPKMDGITLTMKLRENHNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVENKEQKVDDDDGVFAIGGLELNENTKEVSVDG
                     KHIKATPIEFKILSLLMRNAGRVFSADEIYERVWNDNAVNTDTVMVHVRNIREKIEVD
                     PKNPKYLKVVWGVGYKIEKIQR"
     gene            5860..>6278
                     /locus_tag="ACOIAP_003700"
     CDS             5860..>6278
                     /locus_tag="ACOIAP_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGZ2640529.1"
                     /translation="MLDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGG
                     AKNPFEQESFVDNMYKGSYVLYHNMKEEQEGKMIQPSKLFISKETMNYIKNVSKEKDT
                     YDGSETYYTDDSINADFNQNFENWESFIKESGKNLKY"
BASE COUNT         2547 a          600 c         1175 g         1956 t
ORIGIN      
        1 gggaactcag gaggctcaaa ttcaggagac aatggaggga gctcaggcgg ttcaaactca
       61 ggagacaatg gagatagttc aggaggctca aactcaggag ataatggagg aacttcatca
      121 ggcactggtg caaatattgg taaaacagaa taaatattaa taaaataaga gctgtccttt
      181 tatagaaaat attttcttta aagggcagtt tgttttgtat aaaatattga attggttata
      241 atataaggag aaaagcattt atgaaaaaga aaacagtttt aattacagga ggagctagag
      301 gaattggcaa agctatgtct aaagcttttg caaaagaagg ttataatgta ttagtaaatt
      361 ttaataagtc agaaaatgaa gctaaagagt tgtatactag attaaatgaa gaaaattttt
      421 ctataaaact ttttaaggct gatgtttcaa atagagaaga tgtagagaat atggtagatt
      481 attgtataaa agaatttgga ggattggatg tacttgtaaa caatgctggt ataagtcaag
      541 acaagttgtt tacagatata actgatgtag actgggataa tatgatgaat attaatttaa
      601 aaggaagttt ttattgttca caagttgctt taaaatacat gatatcagaa aaaaaaggaa
      661 atataattaa tatatcttca atctggggta tatcaggtgc ttcttgtgaa gtgcattatt
      721 ctataacaaa agcaggtata ataggaatga caaaagcatt agctaaagaa gtaggaccat
      781 caaatattag agtaaatagc atagctccag gtgtcattaa tactgatatg ttatctggat
      841 ataatgagga agatatagat attcttgtgg aagaaactcc tctaatgagg ctaggaactc
      901 cagaagatat agcaaattgt gctattttct tggcatcaga caaatcaaat tttataactg
      961 gtcaagtaat tagtccaaac ggaggatttg ttatttaaaa aaaatgtggt attatataaa
     1021 aataggaaag aataacacga tatactactc ataaacagta tgtgtttata taaattttat
     1081 aaagggaggc atttgatgct agaaggaaaa attataaagg ggattagtgg attttattat
     1141 gtagatacgc ataatggtat ttatgaatgt aaggctagag gaatatttag aaaacataaa
     1201 ataacacctc tggttggtga tagagtcaaa ataagcattg ttgatgagga tgaaaaaaaa
     1261 ggtatcttag aagaaataga cagtagagat acagaactta taagacctcc tatagcaaat
     1321 gtagataagg cactaatagt attcgcaata aaaaatccta aaccaaactt atctctttta
     1381 gatagattta tagttttggc agaaaaagaa aatttagaaa ctgtaataat ccttacaaaa
     1441 gcagatttag atgataatga tacactagaa actgttaaaa aaatatatga acttagtgga
     1501 tacaaagtta ttcctgtaag caatattact aaattaaata tagagaaagt aaaagaagag
     1561 ttaaaagaaa atgtagtagt gtttgcagga ccatctggag ttggaaaatc aagtttacta
     1621 aatgaaatag atgaaaactt taaacttcaa acaggagtgg taagtgataa aataaaaagg
     1681 ggaaaacata ctactcgtca tgctgaactt ttaaaattgg aatttggtgg aatggttgca
     1741 gatacaccag gctttagttc tcttgcactt gaagatatag aggaagttga acttaaagat
     1801 tattttatag aatttgataa atttaatgat tgtaagtttg gttcaaaatg tattcatgaa
     1861 aatgaaccta attgtgctat aaaagaagct gttgcaaatg gagaaatatc taaagaaaga
     1921 tatgagagtt atatacagct actaaatgaa ataagacaaa ataatagtag gaggtattag
     1981 aaacatgatt aaattagcac catcaatatt atcagcagat tttgcaaaat tattagagga
     2041 tgtaagaaag gtagagagtg caggatgtga atatcttcat atcgatgtaa tggatggaca
     2101 ctttgtacca aacattacat taggaccact tgtagtcaaa agtttgaaga aagaaaatat
     2161 aaatatggta tttgatgctc atcttatgat agaaaatcca gaccagtata ttgaagagtt
     2221 tgtaaaagca ggatgtgata taataactgt tcatcaagag gcttgtgttc atctacatag
     2281 aactatacaa aatataaaat cacatggaat aaaagcaggt gtagtgctta atccagctac
     2341 accaatagat actattaaac atgtactacc tgatttagat atggtattat taatgtctgt
     2401 taatcctgga tttggaggac aatcatttat accttgtgtt ttagataaga ttaaagagtt
     2461 aaaagctatt atagatagtc aaggattaaa tattgatata gaagttgatg gtggtataag
     2521 ccctaaaaat gtggataaag ttgtacaagc aggagctaat gtaatagtag caggttctgc
     2581 aatatttgga agtgatgaca ttcaagaaac agttaattta tttagaaaga atgcttctct
     2641 tgaagaatta gtttaaattt aagaatgaaa atctgtattg ttttaaatgg tgaaatagaa
     2701 gattacgaag ttacaagagg tattataatt aaagaatgtt atgactgcat aatatgtgca
     2761 gatggaggag caaatcacac ttataaaatg gaaataatgc cagattatat attaggagac
     2821 ttagattcag tagaagaaga aaagataaac ttctataaaa ataaaggtgt taaatttgaa
     2881 aaatttccat ctaaaaaaga tgagactgat acagagcttt gtcttttttt agctaagaca
     2941 cttaaagcaa atcatattga tttttttggt gctttaggag gtaggattga ccacactctt
     3001 gcaaatataa agctattata ttatttaaaa gaagatggta tatattctag gatactttct
     3061 gataaagaag agatgtatat agttgaaaat gaagaaattt cactgtatgg aaatccagga
     3121 gacactattt ctgtaatagc tataaaaggt gatgctaagg gtgtaacact taccggatta
     3181 gaatatcctc tcgataatta ttatatgaga tactctgtac ctattggaat atcaaatgtt
     3241 atgttgagta attcttgtaa gattaaagta gagcaaggat gtgtacttgt agttagaaat
     3301 ttataaaatt tggttttgac aattgatttt atattgtaga gcagatacaa tcaagtaaaa
     3361 tatatttatg attgtatctg ctttttagta tataattata aatagataat aaactttgac
     3421 ataaggggga ttttttgtgg tagatagtat tatttttgat ttagatggaa cgttgtggga
     3481 ttcaactgaa gaagtatgca aagtttggca ggatgtttta agtaaacata aagaaataga
     3541 tttaagtgtc acaaaagatt tatttagaag tcttatgggg ctttcttttg aggaaatagc
     3601 aaatcgttta tttccaaatt taagtgaaga agaaagaaat aatttattaa atgaatgttc
     3661 tttgaaagaa tgtgaatatt tatctgaaaa tggagctaaa ttatttgatg atatagaaaa
     3721 tactcttaaa ttactatcta aaaaatataa attatttata gtaagtaatt gtcaagctgg
     3781 atatatagaa tcttttttaa aagcacataa actagaacag tattttgtag attttgaatg
     3841 tccaggtaat actggtttgc ataaagggga aaataataaa cttataattg aaagaaataa
     3901 attaaaaaac ccaatctata ttggagatac tcaaggtgat gcaaatagtg ctaagtttgc
     3961 aggtatccct tttatatatg ctaaatatgg atttgggaat gtagatgtat atgattattt
     4021 tatagactca tttaaagatt tgttagaaca tgatatatta aaataggatg agtttaaaaa
     4081 ttatattaaa ataataaaaa agttatgggg ggatttaaaa atggaattac aggatactat
     4141 ttttaaaaga caaagtgtaa gaaagtttaa aaatcaagat gtgtcagatg aagatatttt
     4201 aaaaatgata aaagcagcag gtgcagctcc atcaggaaag aatattcaaa actggcattt
     4261 tgtcattata aaacgtcgtg acttaatgga aaagatagca gatgtgataa ctaaaaagca
     4321 acaagaaata cttgtagaaa tggaaaaagt atcagtagat aaggctaata gatttagaaa
     4381 atttgttaaa aactttacac tattttactt aaaagctcca gttttagtat tagtttttac
     4441 aaaggtatat aatccatcag gatattatga attagagctt atagatgcac ctaaggaaac
     4501 tatagataaa ttattcataa gaaatccagg tatgcagagt ttaggtgctg cgattgaaaa
     4561 ctttacatta tcagcaattg aacttgggta tggttcttgt tggttgacaa gtcaaaacta
     4621 cgcagcagat gaaatagaag ctgttttaga agcagaaact ggatttgaaa aaggagagta
     4681 ttttttaggt gcaatgttgg ctcttggagt gccagaggat aatttgaaga gcccatctaa
     4741 aaaaccagta gaagaaatat gtacatttat aaaataaaag acaataattt ttaagattca
     4801 aaatgagtta aaaataaata gttaaaaata aaaaggtagg ttttattgat attaagttta
     4861 tgtttcaaat cattgattta attaatgcaa taaaaactac cttttttgtg catattaatt
     4921 ttgaataact ccaaatcttt agaaaatctt tagaaaagta tatgtaatat cttaagtttt
     4981 taactttaat attaagtata taaaatgaaa aaactaaatt tatactagag ggaggtctct
     5041 aaggtgtaca ttaaataaaa ataactatta gaaagatata aatatataaa aaaatggaaa
     5101 aacttctatc atattgtata atcatatatg taaagaaaat ttataaatta attggtataa
     5161 aggagattaa aatgaattca tataatattt tggtggtaga agatgaaaag gaaatagcag
     5221 atgctataga gatataccta ttaaatcaag gatataatgt ttttaaagga tacaatggat
     5281 tagaaggact taaggttata gaaaatcaag aaatacattt agcaataatt gatataatga
     5341 tgcctaaaat ggatggaata acacttacaa tgaagcttag agaaaatcat aatttcccag
     5401 taataatgct atctgcaaaa tcagaagaag ttgataaaat aatggggctt aatatagggg
     5461 cagacgatta tgtaacaaaa ccttttaagc ctttagagct attggctaga gtaaactcac
     5521 aacttagaag atacactaag tatttaaata tggttgaaaa taaagagcaa aaagtagatg
     5581 atgatgatgg cgtgtttgca ataggtggat tagaattaaa tgaaaataca aaagaagtta
     5641 gtgttgatgg gaagcatata aaagcaactc ccatagaatt taaaatacta agcttactta
     5701 tgagaaatgc aggaagagtt ttttctgctg atgaaatata tgaaagagtt tggaatgata
     5761 atgctgtaaa tacagataca gttatggtac atgttaggaa tataagggag aaaatagaag
     5821 tagacccaaa aaatcctaaa tatttaaagg tggtgtgggg tgttggatac aaaattgaaa
     5881 aaattcaaag ataaatatat agttactatt atagttttta tacttatgtt atcagcatca
     5941 ttaggtatga ttagtcaata ttctactatt caagcagggg ctaaaggtgg agcaaagaat
     6001 ccatttgaac aggaaagttt tgtagataat atgtataaag gaagttatgt tttatatcat
     6061 aacatgaaag aagaacaaga aggtaagatg atacaaccct caaaactttt tataagtaaa
     6121 gaaactatga actatataaa aaatgtaagt aaagaaaaag atacttatga tggctcagag
     6181 acttattata cagatgatag tattaatgca gattttaatc aaaactttga aaattgggag
     6241 tcttttatta aagaatcagg aaaaaattta aaatatta
//
